WorldWideScience

Sample records for cleared 510k submissions

  1. 78 FR 14097 - Pulse Oximeters-Premarket Notification Submissions [510(k)s]; Guidance for Industry and Food and...

    Science.gov (United States)

    2013-03-04

    ... Federal Register of July 19, 2007 (72 FR 39631), FDA announced the availability of the draft guidance... HUMAN SERVICES Food and Drug Administration Pulse Oximeters--Premarket Notification Submissions... availability of the guidance entitled ``Pulse Oximeters--Premarket Notification Submissions .'' This...

  2. Premarket Notifications (510(k)s)

    Data.gov (United States)

    U.S. Department of Health & Human Services — Medical device manufacturers are required to submit a premarket notification or 510(k) if they intend to introduce a device into commercial distribution for the...

  3. 78 FR 26786 - 510(k) Device Modifications: Deciding When To Submit a 510(k) for a Change to an Existing Device...

    Science.gov (United States)

    2013-05-08

    ..., the Quality System Regulation, at 61 FR 52620 (October 7, 1996), in the response to comment 83... HUMAN SERVICES Food and Drug Administration 510(k) Device Modifications: Deciding When To Submit a 510(k... Administration (FDA) is announcing the public meeting entitled ``510(k) Device ] Modifications: Deciding When...

  4. 75 FR 47307 - Center for Devices and Radiological Health 510(k) Working Group Preliminary Report and...

    Science.gov (United States)

    2010-08-05

    ... Decision Making Preliminary Report and Recommendations; Availability; Request for Comments AGENCY: Food and... of Science in Regulatory Decision Making. Volume I is entitled ``510(k) Working Group Preliminary... Regulatory Decision Making Preliminary Report and Recommendations.'' The recommendations contained in...

  5. Specific heat of rhenium disulfide in 360-510 K temperature range

    International Nuclear Information System (INIS)

    Isobaric specific heat of rhenium disulfide was measured by the method of differential scanning calorimetry in the range of 360-510 K. Thermodynamic functions of rhenium disulfide were calculated using literature data on standard entropy of the compound for the range of 296.15-600 K. 3 refs., 1 fig., 2 tabs

  6. 78 FR 69693 - Draft Guidance for Industry: Recommendations for Premarket Notification (510(k)) Submissions for...

    Science.gov (United States)

    2013-11-20

    ... the draft guidance to the Office of Communication, Outreach and Development (HFM- 40), Center for... Research (HFM-17), Food and Drug Administration, 1401 Rockville Pike, Suite 200N, Rockville, MD...

  7. Fixing a 510(K) Loophole: In Support of The Sound Devices Act of 2012

    OpenAIRE

    Ho, Shuenn (Patrick)

    2014-01-01

    The current medical device regulatory system contains a dangerous loophole. While the voluntary recall of a harmful medical device removes it from the market, new devices that claim they are substantially equivalent to the recalled device can still reach the market through the 510(k) premarket notification process. Devices that have gained regulatory clearance in this fashion have caused considerable harm and are much more likely to be recalled for safety reasons as well. The recently propo...

  8. 78 FR 100 - Guidance for Industry and Food and Drug Administration Staff; Refuse To Accept Policy for 510(k)s...

    Science.gov (United States)

    2013-01-02

    ... checklists for use by FDA review staff. In the Federal Register of August 13, 2012 (77 FR 48159), FDA...; Refuse To Accept Policy for 510(k)s; Availability AGENCY: Food and Drug Administration, HHS. ACTION... entitled ``Refuse to Accept Policy for 510(k)s.'' The purpose of this document is to explain the...

  9. 21 CFR 862.9 - Limitations of exemptions from section 510(k) of the Federal Food, Drug, and Cosmetic Act (the act).

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Limitations of exemptions from section 510(k) of the Federal Food, Drug, and Cosmetic Act (the act). 862.9 Section 862.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY...

  10. 75 FR 82489 - Process for Submissions for Review of Security-Based Swaps for Mandatory Clearing and Notice...

    Science.gov (United States)

    2010-12-30

    ... a CCP for securities transactions is a clearing agency as defined in the Exchange Act and is... methods: Electronic Comments Use the Commission's Internet comment form( http://www.sec.gov/rules/proposed...-based swaps, for the purpose of including transactions and entities that have been structured to...

  11. Clearing, transparency, and collateral

    OpenAIRE

    Francesco Carli; Francesca Carapella; Gaetano Antinolfi

    2014-01-01

    In an environment of Over-The-Counter trading with adverse selection we study traders' incentives to screen their counterparties under different clearing arrangements. When the clearing arrangement is also a choice, traders decide which types of transactions to clear under each arrangement, with signicant consequences for transparency and collateral requirements. The key trade-off is between insurance and the value of information: on one hand risk averse traders want to smooth consumption and...

  12. 78 FR 42809 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2013-07-17

    ... COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule... Government Securities Division July 11, 2013. On May 15, 2013, the Fixed Income Clearing Corporation (``FICC..., 2013), 78 FR 33456 (June 4, 2013) (SR-FICC-2013-05). \\4\\ Email submission by Laura Skinner (June...

  13. Snow-clearing operations

    CERN Multimedia

    EN Department

    2010-01-01

    To facilitate snow clearing operations, which commence at 4.30 in the morning, all drivers of CERN cars are kindly requested to park them together in groups. This will help us greatly assist us in our work. Thank-you for your help. Transport Group / EN-HE Tel. 72202

  14. Hudson_Clearing.m

    OpenAIRE

    Rigby, S.E.

    2014-01-01

    This MATLAB code allows the user to generate a series of keyword files for use with LS-DYNA to predict the blast load and evaluate the effects of blast wave clearing on a finite-sized, deformable target. User doccumentation is provided.

  15. Clear cell sarcoma

    Directory of Open Access Journals (Sweden)

    Pinar Ozuguz

    2014-01-01

    Full Text Available Malignant melanoma (MM of soft tissue, also called clear cell sarcoma (CCS of tendons and aponeuroses, derives from the neural crest. CCS is similar morphologically to MM but has no precursor skin lesion, and instead, has a characteristic chromosomal translocation. Prognosis is related to the tumor size. Early recognition and initial radical surgery is the key to a favorable outcome. The tumor has to be differentiated from other benign and malignant lesions of the soft tissues, such as fibrosarcoma. The demonstration of melanin and a positive immunohistochemical reaction for S-100 protein and HMB-45 can assist in the differential diagnosis. We report the case of a 58-year-old woman with CCS arising from the soft tissue of her little finger.

  16. 77 FR 71848 - Self-Regulatory Organizations; The Options Clearing Corporation; Notice of Filing and Immediate...

    Science.gov (United States)

    2012-12-04

    ... situation, if much of the margin deposited by the relevant Clearing Member is in the form of common stock... Commission, 100 F Street NE., Washington, DC 20549-1090. All submissions should refer to File Number SR-OCC... printing in the Commission's Public Reference Room, 100 F Street NE., Washington, DC 20549 on...

  17. Instructions for Submissions

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    <正>Asian Agricultural Research, as a monthly academic journal, is mainly engaged in research and discussion of agricultural economic issues. Papers on this topic will be preferred. Other topics may touch upon farmers, rural development, rural environment, rural public goods, land science, etc. Submission in electronic form is preferred, including Portable Document Format (pdf) and MS-Word (doc). If you submit

  18. Macroeconomic Dynamics Online Submission

    OpenAIRE

    William Barnett; Stephen Spear

    2004-01-01

    This page is forthcoming in the journal, Macroeconomic Dynamics, as an Announcement from the Editor. The page provides information about the conversion of the journal's submission procedure from on-paper to all electronic. The new system was created by Stephen Spear and is maintained by him on his server at Carnegie Mellon University

  19. To Clear or Not To Clear - That Is the Question

    OpenAIRE

    Downing, Adam; Childs, Corey; Porr, C. A. Shea

    2009-01-01

    Many options exist if you do decide to clear land. Regardless of the option you choose, the primary goal should be the same: to minimize soil loss and movement during and immediately after the land clearing process.

  20. Clearing and vegetation management issues

    International Nuclear Information System (INIS)

    Clearing and continued management of incompatible plant species is critical to maintaining safe and reliable transmission and distribution lines at British Columbia Hydro. As part of a general review of policies regarding rights-of-way, the clearing of BC Hydro rights-of-way was studied by a task team in order to formulate a set of recommended policies and procedures to guide employees in all rights-of-way decisions, and to provide clear direction for resolution of all rights-of-way issues in a cost-effective manner. Issues reviewed were: clearing standards and line security standardization for transmission circuits; clearing rights for removal of trees or management of vegetation beyond the statutory right-of-way; clearing and vegetation management procedures; tree replacement; arboricultural techniques; periodic reviewing of clearing practices; compensation for tree removal; herbicide use; and heritage and wildlife trees. Justification for the recommendation is provided along with alternate options and costs of compliance

  1. Media Language, Clear or Obscure

    DEFF Research Database (Denmark)

    Jakobsen, Bjarne le Fevre; Ejstrup, Michael

    2015-01-01

    Abstract— Be clear, not obscure. One of the four maxims for optimal communication is that it is essential to develop proficiency in being concise and clear. The question is whether this is really a good idea in all contexts. There is some evidence to the contrary. Undoubtedly, we have many contex...

  2. Clear Cell Basal Cell Carcinoma

    OpenAIRE

    Bo Wang; Tracey Harbert; Jennifer Olivella; Daniel Olson; Sarma, Deba P; Stephanie Ortman

    2011-01-01

    Introduction. Clear cell basal cell carcinoma (BCC) is an uncommon and unusual variant of BCC, which is characterized by a variable component of clear cells. The pathogenesis of this histological variant and its clinical significance has not been clarified. Differentiation of this uncommon variant of BCC from other clear cell tumors is important for the treatment. Case Presentation. A 65-year-old male presented with a 0.9 cm dome-shaped lesion on his upper chest. A shave biopsy revealed a der...

  3. Media Language, Clear or Obscure

    DEFF Research Database (Denmark)

    Ejstrup, Michael; le Fevre Jakobsen, Bjarne

    2015-01-01

    Be clear, not obscure. One of the four maxims for optimal communication is that it is essential to develop proficiency in being concise and clear. The question is whether this is really a good idea in all contexts. There is some evidence to the contrary. Undoubtedly, we have many contexts where it...... is important for mutual understanding that we be clear and concise. This is true of instructions for electronic equipment and for household appliances. Here, linguistic brevity and clarity may be preferable, but not in other cases. Culture, globalization, and the recognition of ever faster growth in...

  4. 77 FR 21277 - Customer Clearing Documentation, Timing of Acceptance for Clearing, and Clearing Member Risk...

    Science.gov (United States)

    2012-04-09

    ... for Processing, Clearing, and Transfer of Customer Positions, 76 FR 13101 (Mar. 10, 2011). \\6... (Aug. 1, 2011). \\11\\ See 76 FR 33066 (Jun. 6, 2011). II. Customer Clearing Documentation A... customer when trading with that SD or MSP. \\12\\ See 76 FR 45730 at 45731, Aug. 1, 2011. \\13\\ See...

  5. Proposal Submission System - A Content Management System Approach for Proposal Submission

    OpenAIRE

    Saeed Shadlou; Chai Kinn Pong; Sanath Sukumaran

    2011-01-01

    Submissions of proposals are very often a tedious affair. Proposals which are submitted goes through notonly a complex and tedious process but often the scrutiny of many individuals of different roles. Hence, it isimportant that any automation envisaged goes through a meticulous exercise to achieve the same.Proposal Submission System aims to provide an online proposal submission mechanism, improving thetraditional and physical methods of submission. Such system allows assignment submission to...

  6. 6 CFR 27.210 - Submissions schedule.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Submissions schedule. 27.210 Section 27.210... STANDARDS Chemical Facility Security Program § 27.210 Submissions schedule. (a) Initial Submission. The... Schedule for Covered Facilities. The timeframes in this subsection also apply to covered facilities...

  7. Sustainable energy policy. Submission to the Commonwealth Government

    International Nuclear Information System (INIS)

    This submission is provided by Australian business and industry to the Commonwealth Government in response to the invitation contained in a recent Issues paper. It would appear that the government's concern is primarily related to the link between energy generation and use and greenhouse gas emissions. This submission highlights the roles of demand growth, efficient delivery and effective implementation of policy framework. It is stated that the outset that energy policy should not be driven solely or even primarily by the greenhouse issue - economic sustainability is clearly at least of equal relevance. A viable and appropriate framework is suggested including: no-regrets action domestically; cost effective emission abatement in developing countries and research and development for long term solutions

  8. Plain Language Clear and Simple.

    Science.gov (United States)

    National Literacy Secretariat, Ottawa (Ontario).

    Written for Canadian public servants and written with their help, this handbook presents principles and tips to make official writing clear, concise, and well organized. The handbook defines "plain language" writing as a technique of organizing information in ways that make sense to the reader--using familiar, straightforward words. The handbook…

  9. The art of thinking clearly

    CERN Document Server

    Dobelli, Rolf

    2013-01-01

    The Art of Thinking Clearly by world-class thinker and entrepreneur Rolf Dobelli is an eye-opening look at human psychology and reasoning — essential reading for anyone who wants to avoid “cognitive errors” and make better choices in all aspects of their lives. Have you ever: Invested time in something that, with hindsight, just wasn’t worth it? Or continued doing something you knew was bad for you? These are examples of cognitive biases, simple errors we all make in our day-to-day thinking. But by knowing what they are and how to spot them, we can avoid them and make better decisions. Simple, clear, and always surprising, this indispensable book will change the way you think and transform your decision-making—work, at home, every day. It reveals, in 99 short chapters, the most common errors of judgment, and how to avoid them.

  10. Central Clearing of OTC Derivatives

    DEFF Research Database (Denmark)

    Cont, Rama; Kokholm, Thomas

    2014-01-01

    netting agreements. When a CCP exists for interest rate derivatives, adding a CCP for credit derivatives is shown to decrease overall exposures. These findings are shown to be robust to the statistical assumptions of the model as well as the choice of risk measure used to quantify exposures....... classes are realistically taken into account. We argue that empirically plausible specifications of model parameters lead to the conclusion that central clearing does reduce interdealer exposures: the gain from multilateral netting in a CCP overweighs the loss of netting across asset classes in bilateral...

  11. Proposal Submission System - A Content Management System Approach for Proposal Submission

    Directory of Open Access Journals (Sweden)

    Saeed Shadlou

    2011-04-01

    Full Text Available Submissions of proposals are very often a tedious affair. Proposals which are submitted goes through notonly a complex and tedious process but often the scrutiny of many individuals of different roles. Hence, it isimportant that any automation envisaged goes through a meticulous exercise to achieve the same.Proposal Submission System aims to provide an online proposal submission mechanism, improving thetraditional and physical methods of submission. Such system allows assignment submission to be moreefficient and greater rigor. Online submission provides electronic copy of assignments, which has manybenefits over traditional physical copy submission of assignments. With the implementation of ProposalSubmission System, one can be subjected to the same rigor as traditional means without compromising onquality whilst adhering to the same process workflow.

  12. UMI/Proquest's ETD Submission Project

    OpenAIRE

    Brace, Tim

    2003-01-01

    UMI/Proquest is teaming with Berkeley Electronic Press to provide the infrastructure for an online submission system to institutions that send ETDs to UMI/Proquest. The institution will configure submission pages to its needs and the needs of its students, using the UMI/Proquest site as a staging area. Complete workflow, from student submission, and institutional review, through final upload to the UMI/Proquest dissertation website (and subsequent automatic copying to the institution's libr...

  13. Automatic processing of dominance and submissiveness

    OpenAIRE

    Moors, Agnes; De Houwer, Jan

    2005-01-01

    We investigated whether people are able to detect in a relatively automatic manner the dominant or submissive status of persons engaged in social interactions. Using a variant of the affective Simon task (De Houwer & Eelen, 1998), we demonstrated that the verbal response DOMINANT or SUBMISSIVE was facilitated when it had to be made to a target person that was respectively dominant or submissive. These results provide new information about the automatic nature of appraisals and ...

  14. The ClearPET project

    International Nuclear Information System (INIS)

    The Crystal Clear Collaboration has designed and is building a high-resolution small animal PET scanner. The design is based on the use of the Hamamatsu R7600-M64 multi-anode photomultiplier tube and a LSO/LuYAP phoswich matrix with one to one coupling between the crystals and the photo-detector. The complete system will have 80 PM tubes in four rings with an inner diameter of 137 mm and an axial field of view of 110 mm. The PM pulses are digitized by free-running ADCs and digital data processing determines the gamma energy, the phoswich layer and even the pulse arrival time. Single gamma interactions are recorded and coincidences are found by software. The gantry allows rotation of the detector modules around the field of view. Simulations, and measurements a 2x4 module test set-up predict a spatial resolution of 1.5 mm in the centre of the field of view and a sensitivity of 5.9% for a point source in the centre of the field of view

  15. 28 CFR 51.22 - Premature submissions.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Premature submissions. 51.22 Section 51.22 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR THE ADMINISTRATION OF... § 51.22 Premature submissions. The Attorney General will not consider on the merits: (a) Any...

  16. CO2 Efflux from Cleared Mangrove Peat

    OpenAIRE

    Lovelock, Catherine E.; Roger W Ruess; Feller, Ilka C.

    2011-01-01

    BACKGROUND: CO(2) emissions from cleared mangrove areas may be substantial, increasing the costs of continued losses of these ecosystems, particularly in mangroves that have highly organic soils. METHODOLOGY/PRINCIPAL FINDINGS: We measured CO(2) efflux from mangrove soils that had been cleared for up to 20 years on the islands of Twin Cays, Belize. We also disturbed these cleared peat soils to assess what disturbance of soils after clearing may have on CO(2) efflux. CO(2) efflux from soils de...

  17. 27 CFR 9.99 - Clear Lake.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Clear Lake. 9.99 Section 9... TREASURY LIQUORS AMERICAN VITICULTURAL AREAS Approved American Viticultural Areas § 9.99 Clear Lake. (a) Name. The name of the viticultural area described in this section is “Clear Lake.” (b) Approved...

  18. DOMINANCE OF EXISTENCE: RIOT OR SUBMISSION

    Directory of Open Access Journals (Sweden)

    Vasiljeva A. S.

    2014-03-01

    Full Text Available This article investigates two types of self-actualization and the search for meaning in terms of the totality of existence. The conditions and forms of rebellion and submission are also listed

  19. 75 FR 12803 - Fingerprint Submission Requirements Rule

    Science.gov (United States)

    2010-03-17

    ...Notice of the Compact Council's establishment of a process for initiating noncriminal justice criminal history record checks during times of emergencies and disasters under the authority of the Fingerprint Submission Requirements Rule, title 28 Code of Federal Regulations (CFR), part...

  20. Hyalinizing clear cell carcinoma: A rare entity

    OpenAIRE

    P Venkat Baghirath; J Vijay Kumar; B Hari Vinay

    2011-01-01

    Hyalinizing clear cell carcinoma (HCCC) is an uncommon malignant salivary gland tumor accounting for about 1% of all intra-oral salivary gland tumors. Microscopic diagnosis of clear cell carcinoma may be challenging because of the spectrum of features which frequently overlaps with the other salivary gland tumors that contain clear cells, and thus it may be a diagnosis of exclusion. Here we, report a case of HCCC in a 36 years old female with detailed histological, histochemical and immunohis...

  1. Clear cell carcinoma of the lung.

    OpenAIRE

    Edwards, C; Carlile, A

    1985-01-01

    Six tumours of the lung initially classified as clear cell carcinoma, were studied. Examination of further material by light and electron microscopy showed adenocarcinomatous differentiation in three cases and squamous differentiation in two. One case showed the features of a large cell anaplastic carcinoma. The clear appearance of the cytoplasm in paraffin sections was due to accumulations of glycogen that were partially removed during processing. It is concluded that clear cell carcinoma is...

  2. Primary clear cell sarcoma of bone

    International Nuclear Information System (INIS)

    Clear cell sarcoma is a rare soft tissue sarcoma of young adults with melanocytic differentiation. It occurs predominantly in the soft tissue of extremities, typically involving tendons and aponeuroses. Primary clear cell sarcoma of bone is extremely rare. We report a case of primary clear cell sarcoma of the right first metatarsal in a 48-year-old woman and provide a literature review of the entity. (orig.)

  3. Clearing over-the-counter derivatives

    OpenAIRE

    Ed Nosal

    2011-01-01

    Prior to the financial crisis of 2008, the over-the-counter derivatives market was not required to “clear” transactions. This changed with the signing of the new financial reform legislation, the Dodd–Frank Act on July 21, 2010. Going forward, most OTC derivatives will be cleared through a particular set of institutional arrangements: a regulated clearinghouse. This article provides an overview of how clearing works, the potential benefits of central clearing for OTC derivatives, and the opti...

  4. 76 FR 62421 - Submission for OMB Review; Comment Request; A Generic Submission for Theory Development and...

    Science.gov (United States)

    2011-10-07

    ... published in the Federal Register on August 2, 2011 (76 FR 46307) and allowed 60-days for public comment. No... Submission for Theory Development and Validation (NCI) SUMMARY: Under the provisions of Section 3507(a)(1)(D... Generic Submission for Theory Development and Validation (NCI). Type of Information Collection...

  5. 78 FR 7765 - Submission of Data by State Educational Agencies; Submission Dates for State Revenue and...

    Science.gov (United States)

    2013-02-04

    ... Submission of Data by State Educational Agencies; Submission Dates for State Revenue and Expenditure Reports... agencies (SEAs) of expenditure and revenue data and average daily attendance statistics on ED Form 2447...: (202) 502- 7338 or by email: stephen.cornman@ed.gov ; or Mr. Jumaane Young, NPEFS Project Manager;...

  6. 17 CFR 39.4 - Procedures for implementing derivatives clearing organization rules and clearing new products.

    Science.gov (United States)

    2010-04-01

    ... product until its registration as a derivatives clearing organization is reinstated under the procedures... clearing a new product that is not traded on a designated contract market or a registered derivatives... of the product that make it acceptable for clearing with a certification that the clearing of...

  7. 76 FR 45724 - Clearing Member Risk Management

    Science.gov (United States)

    2011-08-01

    ... techniques or other forms of information technology. Comments may be submitted directly to the Office of... COMMISSION 17 CFR Parts 1 and 23 RIN 3038-AD51 Clearing Member Risk Management AGENCY: Commodity Futures... extensive regulations addressing open access and risk management at the derivatives clearing...

  8. Internalization, Clearing and Settlement, and Liquidity

    NARCIS (Netherlands)

    Degryse, H.A.; van Achter, M.; Wuyts, G.

    2012-01-01

    Abstract: We study the relation between liquidity in financial markets and post-trading fees (i.e. clearing and settlement fees). The clearing and settlement agent (CSD) faces different marginal costs for different types of transactions. Costs are lower for an internalized transaction, i.e. when buy

  9. Acoustics of Clear Speech: Effect of Instruction

    Science.gov (United States)

    Lam, Jennifer; Tjaden, Kris; Wilding, Greg

    2012-01-01

    Purpose: This study investigated how different instructions for eliciting clear speech affected selected acoustic measures of speech. Method: Twelve speakers were audio-recorded reading 18 different sentences from the Assessment of Intelligibility of Dysarthric Speech (Yorkston & Beukelman, 1984). Sentences were produced in habitual, clear,…

  10. Keep Your Kidneys Clear: Kicking Kidney Stones

    Science.gov (United States)

    ... Your Kidneys Clear Keep Your Kidneys Clear Kicking Kidney Stones Some say that passing a kidney stone is like delivering a baby made of razor ... is that, although they can be excruciatingly painful, kidney stones rarely cause permanent damage, and you may be ...

  11. Avoiding common problems during online submission of manuscripts.

    Science.gov (United States)

    Welch, Stephen J

    2007-05-01

    Online submission of manuscripts is normally fast, relatively easy, and timely. However, failure to follow journal instructions, omitting required aspects of manuscripts, and other problems can delay or stop the submission and peer-review process. This article discusses common problems encountered during online submission and advises authors on how to avoid those problems and maximize the efficiency of the online submission process. PMID:17494812

  12. SNOW CLEARING SERVICE WINTER 2001-2002

    CERN Multimedia

    ST-HM Group; Tel. 72202

    2001-01-01

    As usual at this time of the year, the snowing clearing service, which comes under the control of the Transport Group (ST-HM), is preparing for the start of snow-clearing operations (timetable, stand-by service, personnel responsible for driving vehicles and machines, preparation of useful and necessary equipment, work instructions, etc.) in collaboration with the Cleaning Service (ST-TFM) and the Fire Brigade (TIS-FB). The main difficulty for the snow-clearing service is the car parks, which cannot be properly cleared because of the presence of CERN and private vehicles parked there overnight in different parts of the parking areas. The ST-HM Transport Group would therefore like to invite you to park vehicles together in order to facilitate the access of the snow ploughs, thus allowing the car parks to be cleared more efficiently before the personnel arrives for work in the mornings.

  13. Clear Cell Carcinoma and Clear Cell Odontogenic Carcinoma: a Comparative Clinicopathologic and Immunohistochemical Study

    OpenAIRE

    Bilodeau, Elizabeth A.; Hoschar, Aaron P.; Barnes, E. Leon; Hunt, Jennifer L.; Seethala, Raja R.

    2011-01-01

    Clear cell carcinoma or hyalinizing clear cell carcinoma (CCC) and clear cell odontogenic carcinoma (CCOC) are rare, low-grade and typically indolent malignancies that can be diagnostically challenging. In this study the clinicopathologic, histologic, and immunohistochemical features of 17 CCCs and 12 CCOCs are examined. The differential diagnosis of clear cell malignancies in the head and neck is discussed. The relationship of CCCs and CCOCs to other clear cell tumors on the basis of their i...

  14. 28 CFR 100.16 - Cost estimate submission.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Cost estimate submission. 100.16 Section..., COMMUNICATIONS ASSISTANCE FOR LAW ENFORCEMENT ACT OF 1994 § 100.16 Cost estimate submission. (a) The carrier... submission of the cost data for the estimate are as follows: (1) The carrier shall submit to the...

  15. 17 CFR 232.501 - Modular submissions and segmented filings.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Modular submissions and... Modular submissions and segmented filings. An electronic filer may use the following procedures to submit information to the EDGAR system for subsequent inclusion in an electronic filing: (a) Modular submissions....

  16. 48 CFR 1552.232-70 - Submission of invoices.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Submission of invoices... Submission of invoices. As prescribed in 1532.908, insert the following clause: Submission of Invoices (JUN 1996) In order to be considered properly submitted, an invoice or request for contract...

  17. 76 FR 50230 - Center for Devices and Radiological Health 510(k) Clearance Process; Recommendations Proposed in...

    Science.gov (United States)

    2011-08-12

    ... August 5, 2010 (75 FR 47307). After reviewing public comment, CDRH issued a plan of action for.... Comments: Regardless of attendance at the public meeting, interested persons may submit either electronic... adequate information to inform the design of a new medical device regulatory framework for class II...

  18. 75 FR 4402 - Strengthening the Center for Devices and Radiological Health's 510(k) Review Process; Public...

    Science.gov (United States)

    2010-01-27

    ... will include no more than 10 non-FDA participants. Only one participant from an organization or company... substantial equivalence to the device's predicate(s)? If these documents are not sufficient, please describe... controls, and which risks are sufficient to make the device ineligible for de novo classification? 3. If...

  19. High Altitude Clear Air Turbulence Project

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Air Force Flight Dynamics Laboratory conducted the High Altitude Clear Air Turbulence Project in the mid 1960s with the intention of better understanding air...

  20. Primary clear cell carcinoma of the larynx.

    OpenAIRE

    G.Pesavento; Ferlito, A; Recher, G.

    1980-01-01

    The clinical and pathological findings in three patients with clear cell carcinoma of the larynx are described. This type of neoplasm in the larynx is extremely rare. The aggressiveness of the tumour and its high biological malignancy are stressed.

  1. Clear corneal incision in cataract surgery

    Directory of Open Access Journals (Sweden)

    Ammar M Al Mahmood

    2014-01-01

    Full Text Available Since the introduction of sutureless clear corneal cataract incisions, the procedure has gained increasing popularity worldwide because it offers several advantages over the traditional sutured scleral tunnels and limbal incisions. Some of these benefits include lack of conjunctival trauma, less discomfort and bleeding, absence of suture-induced astigmatism, and faster visual rehabilitation. However, an increasing incidence of postoperative endophthalmitis after clear corneal cataract surgery has been reported. Different authors have shown a significant increase up to 15-fold in the incidence of endophthalmitis following clear corneal incision compared to scleral tunnels. The aim of this report is to review the advantages and disadvantages of clear corneal incisions in cataract surgery, emphasizing on wound construction recommendations based on published literature.

  2. Ion clearing the the XLS-ring

    Energy Technology Data Exchange (ETDEWEB)

    Bozoki, E.S.; Halama, H.

    1990-01-01

    The mechanism of ion capture by the beam, their effects on the beam as well as ways to clear the ions are discussed. Special attention is given to these questions for the SXLS ring. 20 refs., 5 figs., 4 tabs.

  3. Ion clearing the the XLS-ring

    International Nuclear Information System (INIS)

    The mechanism of ion capture by the beam, their effects on the beam as well as ways to clear the ions are discussed. Special attention is given to these questions for the SXLS ring. 20 refs., 5 figs., 4 tabs

  4. komunikace značky Clean & Clear

    OpenAIRE

    Nováková, Kateřina

    2009-01-01

    The objective of this thesis is to describe a communication campaign of Clean & Clear brand. A brand owned by Johnson & Johnson company specializing in cosmetics for teenage girls. Campaign is described into details, evaluated in terms of effectiveness of its communication tools by achieving marketing goals over a specified period of time. This thesis should confirm the suitability and effectivity of the communication mix applied for Clean & Clear brand in a specific enviroment of anti-acne c...

  5. Governance of securities clearing and settlement systems

    OpenAIRE

    Daniela Russo; Terry L. Hart; Chryssa Papathanassiou

    2004-01-01

    In the context of securities clearing and settlement systems, the nature of governance arrangements acquires a dimension that goes beyond their traditional function in corporate law. They constitute a tool for regulators and central banks to achieve their respective policy goals relating to market operation, market integrity, and systemic stability. In the light of the analysis of this paper, and pending a further evolution in the regulation of securities clearing and settlement in the Commun...

  6. Skin optical clearing potential of disaccharides.

    Science.gov (United States)

    Feng, Wei; Shi, Rui; Ma, Ning; Tuchina, Daria K; Tuchin, Valery V; Zhu, Dan

    2016-08-01

    Skin optical clearing can significantly enhance the ability of biomedical optical imaging. Some alcohols and sugars have been selected to be optical clearing agents (OCAs). In this work, we paid attention to the optical clearing potential of disaccharides. Sucrose and maltose were chosen as typical disaccharides to compare with fructose, an excellent monosaccharide-OCA, by using molecular dynamics simulation and an ex vivo experiment. The experimental results indicated that the optical clearing efficacy of skin increases linearly with the concentration for each OCA. Both the theoretical predication and experimental results revealed that the two disaccharides exerted a better optical clearing potential than fructose at the same concentration, and sucrose is optimal. Since maltose has an extremely low saturation concentration, the other two OCAs with saturation concentrations were treated topically on rat skin in vivo, and optical coherence tomography imaging was applied to monitor the optical clearing process. The results demonstrated that sucrose could cause a more significant increase in imaging depth and signal intensity than fructose. PMID:27108771

  7. CO2 efflux from cleared mangrove peat.

    Directory of Open Access Journals (Sweden)

    Catherine E Lovelock

    Full Text Available BACKGROUND: CO(2 emissions from cleared mangrove areas may be substantial, increasing the costs of continued losses of these ecosystems, particularly in mangroves that have highly organic soils. METHODOLOGY/PRINCIPAL FINDINGS: We measured CO(2 efflux from mangrove soils that had been cleared for up to 20 years on the islands of Twin Cays, Belize. We also disturbed these cleared peat soils to assess what disturbance of soils after clearing may have on CO(2 efflux. CO(2 efflux from soils declines from time of clearing from ∼10,600 tonnes km(-2 year(-1 in the first year to 3000 tonnes km(2 year(-1 after 20 years since clearing. Disturbing peat leads to short term increases in CO(2 efflux (27 umol m(-2 s(-1, but this had returned to baseline levels within 2 days. CONCLUSIONS/SIGNIFICANCE: Deforesting mangroves that grow on peat soils results in CO(2 emissions that are comparable to rates estimated for peat collapse in other tropical ecosystems. Preventing deforestation presents an opportunity for countries to benefit from carbon payments for preservation of threatened carbon stocks.

  8. Identifying multiple submissions in Internet research: preserving data integrity.

    Science.gov (United States)

    Bowen, Anne M; Daniel, Candice M; Williams, Mark L; Baird, Grayson L

    2008-11-01

    Internet-based sexuality research with hidden populations has become increasingly popular. Respondent anonymity may encourage participation and lower social desirability, but associated disinhibition may promote multiple submissions, especially when incentives are offered. The goal of this study was to identify the usefulness of different variables for detecting multiple submissions from repeat responders and to explore incentive effects. The data included 1,900 submissions from a three-session Internet intervention with a pretest and three post-test questionnaires. Participants were men who have sex with men and incentives were offered to rural participants for completing each questionnaire. The final number of submissions included 1,273 "unique", 132 first submissions by "repeat responders" and 495 additional submissions by the "repeat responders" (N = 1,900). Four categories of repeat responders were identified: "infrequent" (2-5 submissions), "persistent" (6-10 submissions), "very persistent" (11-30 submissions), and "hackers" (more than 30 submissions). Internet Provider (IP) addresses, user names, and passwords were the most useful for identifying "infrequent" repeat responders. "Hackers" often varied their IP address and identifying information to prevent easy identification, but investigating the data for small variations in IP, using reverse telephone look up, and patterns across usernames and passwords were helpful. Incentives appeared to play a role in stimulating multiple submissions, especially from the more sophisticated "hackers". Finally, the web is ever evolving and it will be necessary to have good programmers and staff who evolve as fast as "hackers". PMID:18240015

  9. 76 FR 47529 - Customer Clearing Documentation and Timing of Acceptance for Clearing; Correction

    Science.gov (United States)

    2011-08-05

    ... Street, NW., Washington, DC 20581. SUPPLEMENTARY INFORMATION: In FR Doc. 2011-19365 appearing on page... COMMISSION 17 CFR Parts 1, 23, and 39 RIN 3038-AD51 Customer Clearing Documentation and Timing of Acceptance... August 1, 2011, regarding Customer Clearing Documentation and Timing of Acceptance for Clearing....

  10. 78 FR 35940 - Content of Premarket Submissions for Management of Cybersecurity in Medical Devices; Draft...

    Science.gov (United States)

    2013-06-14

    ... premarket submissions to provide effective cybersecurity management and to reduce the risk that device... Submissions for Management of Cybersecurity in Medical Devices.'' This guidance identifies cybersecurity... draft guidance document entitled ``Content of Premarket Submissions for Management of Cybersecurity...

  11. Oral Cavity Clear Cell Odontogenic Carcinoma.

    Science.gov (United States)

    Ginat, Daniel Thomas; Villaflor, Victoria; Cipriani, Nicole A

    2016-06-01

    A case of clear cell odontogenic carcinoma of the oral cavity is described in this sine qua non radiology-pathology correlation article. CT demonstrated a solid and cystic mass arising from the mandible. Histology demonstrated variably-sized nests of clear to pale eosinophilic cells with occasional central necrosis embedded in a hyalinized to fibrocellular stroma. The specimen was also positive for the characteristic rearrangement of the EWSR1 (22q12) locus in 93.5 % of interphase cells. PMID:25994920

  12. Clear Liquor Scrubbing with Anhydrite Production

    International Nuclear Information System (INIS)

    The objective of this project to develop an advanced flue gas desulfurization (FGD) process that has decreased capital and operating costs, higher SO2 removal efficiency, and better by-product solids quality than existing, commercially available technology. A clear liquor process (which uses a scrubbing liquid with no solids) will be used to accomplish this objective rather than a slurry liquor process (which contains solids). This clear liquor scrubbing (CLS) project is focused on three research areas: (1) Development of a clear liquor scrubbing process that uses a clear solution to remove SO2 from flue gas and can be operated under inhibited-oxidation conditions; (2) Development of an anhydrite process that converts precipitated calcium sulfite to anhydrous calcium sulfate (anhydrite); and (3) Development of an alkali/humidification process to remove HCl from flue gas upstream of the FGD system. The anhydrite process also can be retrofit into existing FGD systems to produce a valuable by-product as an alternative to gypsum. This fits well into another of FETC's PRDA objectives of developing an advanced byproduct recovery subsystem capable of transforming SO2 into a useable byproduct or high-volume valuable commodities of interest. This paper describes the proposed processes, outlines the test approach, and preliminary Phase I test results

  13. Lake Mead--clear and vital

    Science.gov (United States)

    Wessells, Stephen M.; Rosen, Michael

    2013-01-01

    “Lake Mead – Clear and Vital” is a 13 minute documentary relating the crucial role of science in maintaining high water quality in Lake Mead. The program was produced coincident with release of the Lakes Mead and Mohave Circular a USGS publication covering past and on-going research in the lakes and tributaries of the Lake Mead National Recreation Area.

  14. 77 FR 66219 - Clearing Agency Standards

    Science.gov (United States)

    2012-11-02

    ... Payment System Risk, 72 FR 2518 (Jan. 12, 2007). \\34\\ See FMI Report, supra note 32. II. Overview of... to clear credit default swaps. See Exchange Act Release Nos. 60372 (July 23, 2009), 74 FR 37748 (July 29, 2009), 61973 (Apr. 23, 2010), 75 FR 22656 (Apr. 29, 2010) and 63389 (Nov. 29, 2010), 75 FR...

  15. Plant Histology: Clearing and the Optical Section.

    Science.gov (United States)

    Freeman, H. E.

    1985-01-01

    Clearing is a simple and rapid technique in which 75 percent lactic acid is used to remove pigments and cytoplasmic contents of fresh leaves, enabling microscopic view of various internal leaf layers. Procedures for using the technique (which helps students gain a more thorough understanding of plant anatomy) are given. (DH)

  16. Roadmap-Based Level Clearing of Buildings

    KAUST Repository

    Rodriguez, Samuel

    2011-01-01

    In this paper we describe a roadmap-based approach for a multi-agent search strategy to clear a building or multi-story environment. This approach utilizes an encoding of the environment in the form of a graph (roadmap) that is used to encode feasible paths through the environment. The roadmap is partitioned into regions, e.g., one per level, and we design region-based search strategies to cover and clear the environment. We can provide certain guarantees within this roadmap-based framework on coverage and the number of agents needed. Our approach can handle complex and realistic environments where many approaches are restricted to simple 2D environments. © 2011 Springer-Verlag.

  17. Clear cell odontogenic carcinoma: A rare case

    Directory of Open Access Journals (Sweden)

    Garima Jain

    2015-01-01

    Full Text Available Clear cell odontogenic carcinoma is a rare neoplasm with very few cases reported in the literature. We report a case of a 50-year-old female patient with the malignancy at a less common location. Diagnosis was given based on the histopathologic findings. The demographic data and understanding for this tumor needs to be strengthened by reporting all new cases, which are diagnosed, in literature.

  18. Imaging of ovarian clear cell carcinoma

    International Nuclear Information System (INIS)

    The aim of this study is to examine the appearance of ovarian clear cell adenocarcinoma (OCCA) on MR, CT, US. In 39 cases with OCCA, the imaging characteristics of OCCA were evaluated morphologically and classified into three groups, that was, monomural nodule type, multi-mural nodule type and predominantly solid type. Forty-three percent of the patients had endometriosis. Contrast material-enhanced MRI was the most useful method for diagnosis of OCCA. (author)

  19. Renal Clear Cell Carcinoma and Tonsil Metastasis

    OpenAIRE

    Dario Marcotullio; Giannicola Iannella; Gian Franco Macri; Caterina Marinelli; Melissa Zelli; Giuseppe Magliulo

    2013-01-01

    Renal cell carcinoma is the most common renal tumor in adults. Clear cell carcinoma represents 85% of all histological subtypes. In February 2012 a 72-year-old woman came to our department due to the appearance of massive hemoptysis and pharyngodinia. Previously, this patient was diagnosed with a renal cell carcinoma treated with left nephrectomy. We observed an exophytic, grayish, and ulcerated mass in the left tonsillar lodge and decided to subject the patient to an immediate tonsillectomy....

  20. Internet compromise clears way for WSIS agreement

    CERN Document Server

    Ermert, M

    2003-01-01

    A working group under the leadership of United Nations Secretary General Kofi Annan himself will try to resolve the deep differences on the question of Internet governance, officials said here. The group, whose exact membership wasn't immediately clear, is to propose a solution to the controversial issue that has given negotiators at the World Summit of the Information Society (WSIS) a headache (1/2 page).

  1. Imaging of ovarian clear cell carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Hayashi, Toshihiko; Sawano, Seishi; Yamada, Keiko [Japanese Foundation for Cancer Research, Tokyo (Japan). Hospital] (and others)

    1999-12-01

    The aim of this study is to examine the appearance of ovarian clear cell adenocarcinoma (OCCA) on MR, CT, US. In 39 cases with OCCA, the imaging characteristics of OCCA were evaluated morphologically and classified into three groups, that was, monomural nodule type, multi-mural nodule type and predominantly solid type. Forty-three percent of the patients had endometriosis. Contrast material-enhanced MRI was the most useful method for diagnosis of OCCA. (author)

  2. 76 FR 38219 - Submission for OMB Review

    Science.gov (United States)

    2011-06-29

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review AGENCY: Overseas Private Investment Corporation (OPIC). ACTION: Request...), agencies are required to publish a Notice in the Federal Register notifying the public that the agency...

  3. 76 FR 38220 - Submission for OMB Review

    Science.gov (United States)

    2011-06-29

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review AGENCY: Overseas Private Investment Corporation (OPIC). ACTION: Request...), agencies are required to publish a Notice in the Federal Register notifying the public that the agency...

  4. 77 FR 60160 - Submission for OMB Review

    Science.gov (United States)

    2012-10-02

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review AGENCY: Overseas Private Investment Corporation (OPIC). ACTION: Request...), agencies are required to publish a Notice in the Federal Register notifying the public that the agency...

  5. 76 FR 38221 - Submission for OMB Review

    Science.gov (United States)

    2011-06-29

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review AGENCY: Overseas Private Investment Corporation (OPIC). ACTION: Request...), agencies are required to publish a Notice in the Federal Register notifying the public that the agency...

  6. 77 FR 33497 - Submission for OMB Review

    Science.gov (United States)

    2012-06-06

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review AGENCY: Overseas Private Investment Corporation (OPIC). ACTION: Request...), agencies are required to publish a Notice in the Federal Register notifying the public that the agency...

  7. Notebook paper: TNO instance search submission 2011

    NARCIS (Netherlands)

    Schavemaker, J.G.M.; Eendebak, P.T.; Staalduinen, M. van; Kraaij, W.

    2011-01-01

    The TNO instance search submission to TRECVID 2011 consisted of three different runs: one is using an exhaustive keypoint search, one is using a bag-of-visual-words approach and one is using open-source face-recognition software. Our run approaches: Briefly, what approach or combination of approache

  8. 40 CFR 725.27 - Submissions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Submissions. 725.27 Section 725.27 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT REPORTING.... (c) Requirements specific to test marketing exemptions (TMEs) are described in §§ 725.350 and...

  9. 18 CFR 1b.19 - Submissions.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Submissions. 1b.19 Section 1b.19 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT..., which may consist of a statement of fact, argument, and/or memorandum of law, with such...

  10. Rapid radiative clearing of protoplanetary discs

    CERN Document Server

    Haworth, Thomas J; Owen, James E

    2015-01-01

    The lack of observed transition discs with inner gas holes of radii greater than ~50AU implies that protoplanetary discs dispersed from the inside out must remove gas from the outer regions rapidly. We investigate the role of photoevaporation in the final clearing of gas from low mass discs with inner holes. In particular, we study the so-called "thermal sweeping" mechanism which results in rapid clearing of the disc. Thermal sweeping was originally thought to arise when the radial and vertical pressure scale lengths at the X-ray heated inner edge of the disc match. We demonstrate that this criterion is not fundamental. Rather, thermal sweeping occurs when the pressure maximum at the inner edge of the dust heated disc falls below the maximum possible pressure of X-ray heated gas (which depends on the local X-ray flux). We derive new critical peak volume and surface density estimates for rapid radiative clearing which, in general, result in rapid dispersal happening less readily than in previous estimates. Thi...

  11. Nitrous oxide flux following tropical land clearing

    Science.gov (United States)

    Luizao, Flavio; Luizao, Regina; Matson, Pamela; Livingston, Gerald; Vitousek, Peter

    1989-01-01

    The importance of seasonal cycles of N2O flux from tropical ecosystems and the possibility that tropical deforestation could contribute to the ongoing global increase in N2O concentrations were assessed by measuring N2O flux from forest, cleared land, and pasture over an annual cycle in the central Amazon. A pasture that had been converted from tropical forest had threefold greater annual N2O flux than a paired forest site; similar results were obtained in spot measurements in other pastures. If these results are general, such tropical pastures represent a globally significant source of increased N2O.

  12. A gap clearing kicker for Main Injector

    CERN Document Server

    Kourbanis, I; Biggs, J; Brown, B; Capista, D; Jensen, C C; Krafczyk, G E; Morris, D K; Scott, D; Seiya, K; Ward, S R; Wu, G; Yang, M -J

    2012-01-01

    Fermilab Main Injector has been operating at high Beam Power levels since 2008 when multi-batch slip stacking became operational. In order to maintain and increase the beam power levels the localized beam loss due to beam left over in the injection kicker gap during slip stacking needs to be addressed. A set of gap clearing kickers that kick any beam left in the injection gap to the beam abort have been built. The kickers were installed in the summer of 2009 and became operational in November of 2010. The kicker performance and its effect on the beam losses will be described.

  13. Greenhouse problem in the Amazon jungle clearing

    International Nuclear Information System (INIS)

    This paper discusses the contribution of Amazon jungle clearing to the greenhouse problem and makes an assessment of long-run prospects. The introductory sections pose the problem from both international and Brazilian perspectives. The next section describes major features of the Amazonia ecosystems and presents methods and evidence on deforestation and on its impact on carbon dioxide emissions. Based upon cross-section information for a sample of municipalities in the Brazilian Amazon, the following section estimates elasticities of deforestation in relation to major economic factors- government policies included- and uses them to make projections for the future pace of deforestation. The last section discusses policy alternatives to slow down forest conversion

  14. CHINA'S WORST OIL LEAK CLEARED EXPENSIVELY

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ Eight days and nights of clean-up efforts after the worst oil leak ever in Chinese waters, the aftermath of a collision between two foreign ships happening at 9:35 pm on December 7 about 8 nautical miles away from the mouth of the Pearl River and near the Danjiang Island, have finally paid off. So far, hundreds of tons of waste oil and polluted water have been cleared up. A large area of oil spills has been cleaned thanks to the prompt and proper operation launched just two hours after the accident.

  15. PLANETARY CHAOTIC ZONE CLEARING: DESTINATIONS AND TIMESCALES

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, Sarah; Malhotra, Renu [Lunar and Planetary Laboratory, The University of Arizona, Tucson, AZ 85721 (United States)

    2015-01-20

    We investigate the orbital evolution of particles in a planet's chaotic zone to determine their final destinations and their timescales of clearing. There are four possible final states of chaotic particles: collision with the planet, collision with the star, escape, or bounded but non-collision orbits. In our investigations, within the framework of the planar circular restricted three body problem for planet-star mass ratio μ in the range 10{sup –9} to 10{sup –1.5}, we find no particles hitting the star. The relative frequencies of escape and collision with the planet are not scale-free, as they depend upon the size of the planet. For planet radius R{sub p} ≥ 0.001 R{sub H} where R{sub H} is the planet's Hill radius, we find that most chaotic zone particles collide with the planet for μ ≲ 10{sup –5}; particle scattering to large distances is significant only for higher mass planets. For fixed ratio R{sub p} /R{sub H} , the particle clearing timescale, T {sub cl}, has a broken power-law dependence on μ. A shallower power law, T {sub cl} ∼ μ{sup –1/3}, prevails at small μ where particles are cleared primarily by collisions with the planet; a steeper power law, T {sub cl} ∼ μ{sup –3/2}, prevails at larger μ where scattering dominates the particle loss. In the limit of vanishing planet radius, we find T {sub cl} ≈ 0.024 μ{sup –3/2}. The interior and exterior boundaries of the annular zone in which chaotic particles are cleared are increasingly asymmetric about the planet's orbit for larger planet masses; the inner boundary coincides well with the classical first order resonance overlap zone, Δa {sub cl,} {sub int} ≅ 1.2 μ{sup 0.28} a{sub p} ; the outer boundary is better described by Δa {sub cl,} {sub ext} ≅ 1.7 μ{sup 0.31} a{sub p} , where a{sub p} is the planet-star separation.

  16. Effects Of The Contingency For Homework Submission On Homework Submission And Quiz Performance In A College Course

    OpenAIRE

    Ryan, Carolyn S.; Hemmes, Nancy S.

    2005-01-01

    Effects of the contingency for submission of homework assignments on the probability of assignment submission and on quiz grades were assessed in an undergraduate psychology course. Under an alternating treatments design, each student was assigned to a points condition for 5 of 10 quiz-related homework assignments corresponding to textbook chapters. Points were available for homework submission under this condition; points were not available under the no-points condition. The group-mean perce...

  17. Planetary chaotic zone clearing: destinations and timescales

    CERN Document Server

    Morrison, Sarah

    2014-01-01

    We investigate the orbital evolution of particles in a planet's chaotic zone to determine their final destinations and their timescales of clearing. There are four possible final states of chaotic particles: collision with the planet, collision with the star, escape, or bounded but non-collision orbits. In our investigations, within the framework of the planar circular restricted three body problem for planet-star mass ratio $\\mu$ in the range $10^{-9}$ to $10^{-1.5}$, we find no particles hitting the star. The relative frequencies of escape and collision with the planet are not scale-free, as they depend upon the size of the planet. For planet radius $R_p\\ge0.001R_H$ where $R_H$ is the planet's Hill radius, we find that most chaotic zone particles collide with the planet for $\\mu\\lesssim10^{-5}$; particle scattering to large distances is significant only for higher mass planets. For fixed ratio $R_p/R_H$, the particle clearing timescale, $T_{cl}$, has a broken power-law dependence on $\\mu$. A shallower power...

  18. The Protease Ste24 Clears Clogged Translocons.

    Science.gov (United States)

    Ast, Tslil; Michaelis, Susan; Schuldiner, Maya

    2016-01-14

    Translocation into the endoplasmic reticulum (ER) is the first step in the biogenesis of thousands of eukaryotic endomembrane proteins. Although functional ER translocation has been avidly studied, little is known about the quality control mechanisms that resolve faulty translocational states. One such faulty state is translocon clogging, in which the substrate fails to properly translocate and obstructs the translocon pore. To shed light on the machinery required to resolve clogging, we carried out a systematic screen in Saccharomyces cerevisiae that highlighted a role for the ER metalloprotease Ste24. We could demonstrate that Ste24 approaches the translocon upon clogging, and it interacts with and generates cleavage fragments of the clogged protein. Importantly, these functions are conserved in the human homolog, ZMPSTE24, although disease-associated mutant forms of ZMPSTE24 fail to clear the translocon. These results shed light on a new and critical task of Ste24, which safeguards the essential process of translocation. PMID:26771486

  19. Selecting the right journal for your submission

    OpenAIRE

    Welch, Stephen J.

    2012-01-01

    Increasing pressure on researchers and academic clinicians to publish high volumes of work in highly visible publication outlets means that authors must have a finely tuned, efficient process for submission. One of the key decisions every author must make is where to submit their paper. This article addresses several important components to making that decision, including (I) topic match; (II) acceptance/rejection rate of the journal; (III) speed of review/publication; (IV) distribution of an...

  20. 7 CFR 28.178 - Submission of cotton samples.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Submission of cotton samples. 28.178 Section 28.178... REGULATIONS COTTON CLASSING, TESTING, AND STANDARDS Classification for Foreign Growth Cotton § 28.178 Submission of cotton samples. Samples of cotton submitted to a Classing Office for classification...

  1. 7 CFR 400.706 - Review of submission.

    Science.gov (United States)

    2010-01-01

    ... and Rates of Premium § 400.706 Review of submission. (a) Prior to providing the submission to the... limited in the length of time or the number of delays. However, delays may make implementation of the... RMA are not sufficient to support the review and implementation of the product; (2) The premium...

  2. 78 FR 38010 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-06-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... fishery management organizations. Revision: Submission of trip tickets is now all electronic, resulting...

  3. 7 CFR 900.25 - Advance submission of testimony.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Advance submission of testimony. 900.25 Section 900.25... § 900.25 Advance submission of testimony. Any person proposing an amendment to a Federal milk marketing agreement or order under § 900.3 of this part, when participating as a witness, shall make copies of his...

  4. 19 CFR 177.2 - Submission of ruling requests.

    Science.gov (United States)

    2010-04-01

    ... citations affecting § 177.2, see the List of CFR Sections Affected, which appears in the Finding Aids... 19 Customs Duties 2 2010-04-01 2010-04-01 false Submission of ruling requests. 177.2 Section 177.2... TREASURY (CONTINUED) ADMINISTRATIVE RULINGS General Ruling Procedure § 177.2 Submission of ruling...

  5. 20 CFR 632.20 - Submission of grant application.

    Science.gov (United States)

    2010-04-01

    ... NATIVE AMERICAN EMPLOYMENT AND TRAINING PROGRAMS Program Planning, Application and Modification Procedures § 632.20 Submission of grant application. (a) Beginning with 1985 or the first designation period... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Submission of grant application....

  6. 78 FR 76748 - Citizen Petition Submission; Technical Amendment

    Science.gov (United States)

    2013-12-19

    ...The Food and Drug Administration (FDA) is modernizing its administrative regulations regarding submission of citizen petitions to explicitly provide for electronic submission. The current regulation does not recognize electronic methods for submitting citizen petitions; thus, this action will enable efficiency and ease in the filing of citizen...

  7. 22 CFR 51.8 - Submission of currently valid passport.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Submission of currently valid passport. 51.8 Section 51.8 Foreign Relations DEPARTMENT OF STATE NATIONALITY AND PASSPORTS PASSPORTS General § 51.8 Submission of currently valid passport. (a) When applying for a new passport, an applicant must submit...

  8. 7 CFR 900.31 - Electronic submission of hearing documents.

    Science.gov (United States)

    2010-01-01

    ... and Marketing Orders § 900.31 Electronic submission of hearing documents. To the extent practicable... 7 Agriculture 8 2010-01-01 2010-01-01 false Electronic submission of hearing documents. 900.31 Section 900.31 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL...

  9. 7 CFR 900.41 - Electronic document submission standards.

    Science.gov (United States)

    2010-01-01

    ... Agreements and Marketing Orders § 900.41 Electronic document submission standards. To the extent practicable... 7 Agriculture 8 2010-01-01 2010-01-01 false Electronic document submission standards. 900.41 Section 900.41 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL...

  10. 32 CFR 310.41 - Suspense for submission of reports.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Suspense for submission of reports. 310.41 Section 310.41 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) PRIVACY PROGRAM DOD PRIVACY PROGRAM Reports § 310.41 Suspense for submission of reports....

  11. 40 CFR 60.4160 - Submission of Hg allowance transfers.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Submission of Hg allowance transfers... Times for Coal-Fired Electric Steam Generating Units Hg Allowance Transfers § 60.4160 Submission of Hg allowance transfers. An Hg authorized account representative seeking recordation of a Hg allowance...

  12. 76 FR 4873 - Notice of Submission for OMB Review

    Science.gov (United States)

    2011-01-27

    ... Review: New. Title of Collection: Striving Readers Comprehensive Literacy Discretionary Grants. OMB... Notice of Submission for OMB Review AGENCY: Department of Education. ACTION: Comment request. SUMMARY..., Office of Management invites comments on the submission for OMB review as required by the...

  13. 75 FR 30006 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-05-28

    ... Education Type of Review: New. Title: Striving Readers Comprehensive Literacy State Formula Grant... Submission for OMB Review; Comment Request AGENCY: Department of Education. SUMMARY: The Acting Director... invites comments on the submission for OMB review as required by the Paperwork Reduction Act of...

  14. Nuclear threat. A clear and present danger

    International Nuclear Information System (INIS)

    It was disappointed at the discussion in the review conference of the NPT held in 2005. The fact may be caused by the estrangement between the international urgent issues related to the non-proliferation and the effectiveness of archaic measures through the NPT. However, it should not be recognized that the international obligation and worth of NPT has been gone. The NPT referred the typical international situation under the cold war era. Although several permanent issues of the nuclear non-proliferation exist in current discussions, the activities relevant to the NPT may not be effect against newly unstable situations after the September 11th of 2001. Urgent challenges to be taken are that we must strictly analyze the interventions between 'the clear and present danger' of our world and the nuclear herms, and must take appropriate actions toward them without influences from previous international situations that might be subsisted in current international treaties and agreements. This paper identified the features of nuclear threats based on the four categories and examined the possibilities of nuclear terrorism from previous facts with the inductive inference. The results identified the possibility of nuclear facility attack and of radioactive materials theft by the Polico-Religious Groups and others are stood out. The authors would suggest the important of urgent recognition to establish the certain security system against nuclear terrorism. (author)

  15. MI Gap Clearing Kicker Magnet Design Review

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Chris; /Fermilab

    2008-10-01

    The kicker system requirements were originally conceived for the NOvA project. NOvA is a neutrino experiment located in Minnesota. To achieve the desired neutrino flux several upgrades are required to the accelerator complex. The Recycler will be used as a proton pre-injector for the Main Injector (MI). As the Recycler is the same size as the MI, it is possible to do a single turn fill ({approx}11 {micro}sec), minimizing the proton injection time in the MI cycle and maximizing the protons on target. The Recycler can then be filled with beam while the MI is ramping to extract beam to the target. To do this requires two new transfer lines. The existing Recycler injection line was designed for 10{pi} pbar beams, not the 20{pi} proton beams we anticipate from the Booster. The existing Recycler extraction line allows for proton injection through the MI, while we want direct injection from the Booster. These two lines will be decommissioned. The new injection line from the MI8 line into the Recycler will start at 848 and end with injection kickers at RR104. The new extraction line in the RR30 straight section will start with a new extraction kicker at RR232 and end with new MI injection kickers at MI308. Finally, to reduce beam loss activation in the enclosure, a new gap clearing kicker will be used to extract uncaptured beam created during the slip stack injection process down the existing dump line. It was suggested that the MI could benefit from this type of system immediately. This led to the early installation of the gap clearing system in the MI, followed by moving the system to Recycler during NOvA. The specifications also changed during this process. Initially the rise and fall time requirements were 38 ns and the field stability was {+-}1%. The 38 ns is based on having a gap of 2 RF buckets between injections. (There are 84 RF buckets that can be filled from the Booster for each injection, but 82 would be filled with beam. MI and Recycler contain 588 RF buckets

  16. Clear cell renal cell tumors: Not all that is "clear" is cancer.

    Science.gov (United States)

    Williamson, Sean R; Cheng, Liang

    2016-07-01

    Continued improvement of our understanding of the clinical, histologic, and genetic features of renal cell tumors has progressively evolved renal tumor classification, revealing an expanding array of distinct tumor types with different implications for prognosis, patient counseling, and treatment. Although clear cell renal cell carcinoma is unequivocally the most common adult renal tumor, there is growing evidence that some "clear cell" renal neoplasms, such as exemplified by multilocular cystic clear cell renal neoplasm of low malignant potential (formerly multilocular cystic renal cell carcinoma), do not have the same potential for insidious progression and metastasis, warranting reclassification as low malignant potential tumors or benign neoplasms. Still other novel tumor types such as clear cell papillary renal cell carcinoma have been more recently recognized, which similarly have shown a conspicuous absence of aggressive behavior to date, suggesting that these too may be recategorized as noncancerous or may be premalignant neoplasms. This importance for prognosis is increasingly significant in the modern era, in which renal masses are increasingly found incidentally by imaging techniques at a small tumor size, raising consideration for less aggressive management options guided by renal mass biopsy diagnosis, including imaging surveillance, tumor ablation, or partial nephrectomy. PMID:26988177

  17. When a Cleared Rape Is Not Cleared: A Multilevel Study of Arrest and Exceptional Clearance.

    Science.gov (United States)

    Walfield, Scott M

    2016-05-01

    As rape remains one of the most underreported and least likely to be cleared of the violent crimes, it is of paramount importance to understand the factors associated with the likelihood of a case being cleared by law enforcement. This study uses data from the National Incident-Based Reporting System (NIBRS) and the Law Enforcement Management and Administrative Statistics (LEMAS), and a multilevel modeling approach to examine the relationship between victim, offender, incident, and police department characteristics contrasting the two types of clearance: arrest and exceptional clearance. The latter occurs due to reasons outside of law enforcement's control and despite being considered cleared, the offender is not arrested, charged, nor turned over for prosecution. Of the 16,231 cleared rapes in 238 departments, nearly half (47%) results in exceptional clearance when the victim refuses to cooperate or when prosecution is declined. Incident-level variables have a greater effect on the likelihood of exceptional clearance than victim and offender variables. The department explained a nontrivial amount of variation in the dependent variable, as 37% of the variance in type of clearance was between-department variation. Implications for future research on exceptional clearance and NIBRS are discussed. PMID:25646164

  18. 76 FR 45730 - Customer Clearing Documentation and Timing of Acceptance for Clearing

    Science.gov (United States)

    2011-08-01

    ... derivatives clearing organization (DCO) level.\\4\\ \\4\\ See, e.g., 76 FR 3698 (Jan. 20, 2011) (Risk Management... permitting them to do so. \\5\\ 75 FR 70152 (Nov. 17, 2010) (Implementation of Conflicts of Interest Policies and Procedures by Futures Commission Merchants and Introducing Brokers); 75 FR 71391 (Nov. 23,...

  19. MODIS Collection 6 Clear Sky Restoral (CSR): Filtering Cloud Mast 'Not Clear' Pixels

    Science.gov (United States)

    Meyer, Kerry G.; Platnick, Steven Edward; Wind, Galina; Riedi, Jerome

    2014-01-01

    Correctly identifying cloudy pixels appropriate for the MOD06 cloud optical and microphysical property retrievals is accomplished in large part using results from the MOD35 1km cloud mask tests (note there are also two 250m subpixel cloud mask tests that can convert the 1km cloudy designations to clear sky). However, because MOD35 is by design clear sky conservative (i.e., it identifies "not clear" pixels), certain situations exist in which pixels identified by MOD35 as "cloudy" are nevertheless likely to be poor retrieval candidates. For instance, near the edge of clouds or within broken cloud fields, a given 1km MODIS field of view (FOV) may in fact only be partially cloudy. This can be problematic for the MOD06 retrievals because in these cases the assumptions of a completely overcast homogenous cloudy FOV and 1-dimensional plane-parallel radiative transfer no longer hold, and subsequent retrievals will be of low confidence. Furthermore, some pixels may be identified by MOD35 as "cloudy" for reasons other than the presence of clouds, such as scenes with thick smoke or lofted dust, and should therefore not be retrieved as clouds. With such situations in mind, a Clear Sky Restoral (CSR) algorithm was introduced in C5 that attempts to identify pixels expected to be poor retrieval candidates. Table 1 provides SDS locations for CSR and partly cloudy (PCL) pixels.

  20. 76 FR 11498 - Submission for OMB Review; Comment Request; Generic Submission of Technology Transfer Center (TTC...

    Science.gov (United States)

    2011-03-02

    ... Submission of Technology Transfer Center (TTC) External Customer Satisfaction Surveys (NCI) SUMMARY: Under...) External Customer Satisfaction Surveys (NCI). Type of Information Collection Request: New. Need and Use of... information collection was previously published in the Federal Register on December 23, 2010 (75 FR 80830)...

  1. Apixaban and atrial fibrillation: no clear advantage.

    Science.gov (United States)

    2014-02-01

    For the prevention of thromboembolic events in patients with atrial fibrillation and a high thrombotic risk, the standard treatment is warfarin, an anticoagulant. Dabigatran, a thrombin inhibitor, is the alternative when warfarin fails to maintain the INR within the therapeutic range. Patients with a moderate thrombotic risk may receive either warfarin or low-dose aspirin. Apixaban, a factor Xa inhibitor anticoagulant, has been authorised in the European Union for use in patients with non-valvular atrial fibrillation and a moderate or high risk of thrombosis. In a double-blind, randomised non-inferiority trial versus warfarin in 18 201 patients, the incidence of stroke or systemic embolism was lower in the apixaban group (average 1.3 versus 1.6 events per 100 patient-years; p = 0.01). This difference was mainly due to a lower incidence of haemorrhagic stroke and did not result in a clear decline in mortality. In addition, these results are undermined by multiple methodological flaws. Clinical evaluation included no trials comparing apixaban with dabigatran; any indirect comparison would be risky given the poor quality of the clinical assessment of both drugs in atrial fibrillation. A double-blind, randomised trial including 5598 patients compared apixaban with aspirin but provided little information on these options in patients with a moderate risk of thrombosis, as most patients were at high risk. In clinical trials, major bleeding events were less frequent with apixaban than with warfarin (average 2.1 versus 3.1 events per 100 patient-years), but they were more frequent with apixaban than with aspirin (1.4 versus 0.9 events per 100 patient-years). In 2013, there is no way of monitoring the anticoagulant activity of apixaban in routine clinical practice, and there is no antidote in case of overdose; the same is true for dabigatran. Apixaban is a substrate for various cytochrome P450 isoenzymes and for P-glycoprotein, creating a risk of multiple drug

  2. Clear Cell Basal Cell Carcinoma with Sialomucin Deposition

    OpenAIRE

    Kim, Do Young; Cho, Sung Bin; Chung, Kee Yang; Kim, You Chan

    2006-01-01

    Clear cell basal cell carcinoma (BCC) is a variant of BCC with a characteristic clear cell component that may occupy all or part of the tumor islands. Periodic acid-Schiff (PAS) staining for glycogen is variably positive, and mild deposition of sulfated mucin has been noted. However, to our knowledge, clear cell BCC with sialomucin deposition has not been reported. Here we report a case of clear cell BCC showing sialomucin deposition. The clear tumor cells stained with PAS and showed incomple...

  3. BABAR Web job submission with Globus Authentication and AFS Access

    International Nuclear Information System (INIS)

    We present two versions of a grid job submission system produced for the BaBar experiment. Both use globus job submission to process data spread across various sites, producing output which can be combined for analysis. The problems encountered with authorization and authentication, data location, job submission, and the input and output sandboxes are described, as are the solutions. The total system is still some way short of the aims of enterprises such as the EDG, but represent a significant step along the way

  4. Water Resources Research supports water economics submissions

    Science.gov (United States)

    Griffin, Ronald C.

    2012-09-01

    AGU's international interdisciplinary journal Water Resources Research (WRR) publishes original contributions in hydrology; the physical, chemical, and biological sciences; and the social and policy sciences, including economics, systems analysis, sociology, and law. With the rising relevance of water economics and related social sciences, the editors of WRR continue to encourage submissions on economics and policy. WRR was originally founded in the mid 1960s by Walter Langbein and economist Allen Kneese. Several former WRR editors have been economists—including David Brookshire, Ron Cummings, and Chuck Howe—and many landmark articles in water economics have been published in WRR.

  5. Longbow: A Lightweight Remote Job Submission Tool

    Directory of Open Access Journals (Sweden)

    James Gebbie-Rayet

    2016-01-01

    Full Text Available We present Longbow, a lightweight console-based remote job submission tool and library. Longbow allows the user to quickly and simply run jobs on high performance computing facilities without leaving their familiar desktop environment. Not only does Longbow greatly simplify the management of compute- intensive jobs for experienced researchers, it also lowers the technical barriers surrounding high perfor-mance computation for the next generation of scientists and engineers. Longbow has already been used to remotely submit jobs in a number of projects and has the potential to redefine the manner in which high performance computers are used.

  6. Guidelines for manuscript submission in the peer-reviewed pharmacological literature.

    Science.gov (United States)

    Mullane, Kevin; Enna, S J; Piette, Jacques; Williams, Michael

    2015-10-01

    Recent reports have highlighted studies in biomedical research that cannot be reproduced, tending to undermine the credibility, relevance and sustainability of the research process. To address this issue, a number of factors can be monitored to improve the overall probability of reproducibility. These include: (i) shortcomings in experimental design and execution that involve hypothesis conceptualization, statistical analysis, and data reporting; (ii) investigator bias and error; (iii) validation of reagents including cells and antibodies; and (iv) fraud. Historically, research data that have undergone peer review and are subsequently published are then subject to independent replication via the process of self-correction. This often leads to refutation of the original findings and retraction of the paper by which time considerable resources have been wasted in follow-on studies. New NIH guidelines focused on experimental conduct and manuscript submission are being widely adopted in the peer-reviewed literature. These, in their various iterations, are intended to improve the transparency and accuracy of data reporting via the use of checklists that are often accompanied by "best practice" guidelines that aid in validating the methodologies and reagents used in data generation. The present Editorial provides background and context to a newly developed checklist for submissions to Biochemical Pharmacology that is intended to be clear, logical, useful and unambiguous in assisting authors in preparing manuscripts and in facilitating the peer review process. While currently optional, development of this checklist based on user feedback will result in it being mandatory within the next 12 months. PMID:26208784

  7. 19 CFR 10.522 - Submission of certificate of eligibility.

    Science.gov (United States)

    2010-04-01

    ...-Singapore Free Trade Agreement Tariff Preference Level § 10.522 Submission of certificate of eligibility. An importer who claims preferential tariff treatment on a non-originating cotton or man-made fiber...

  8. 19 CFR 10.608 - Submission of certificate of eligibility.

    Science.gov (United States)

    2010-04-01

    ...-Central America-United States Free Trade Agreement Tariff Preference Level § 10.608 Submission of certificate of eligibility. An importer who claims preferential tariff treatment on a non-originating...

  9. 75 FR 30106 - Terrorism Risk Insurance Program; Litigation Management Submissions

    Science.gov (United States)

    2010-05-28

    ... Terrorism Risk Insurance Program; Litigation Management Submissions AGENCY: Departmental Offices. ACTION..., the Terrorism Risk Insurance Program Office is seeking comments regarding Litigation Management..., preferably an original and two copies) to: Terrorism Risk Insurance Program, Public Comment Record,...

  10. 40 CFR 86.079-39 - Submission of maintenance instructions.

    Science.gov (United States)

    2010-07-01

    ... and Heavy-Duty Engines, and for 1985 and Later Model Year New Gasoline Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.079-39 Submission of...

  11. 77 FR 25440 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-04-30

    ... and to facilitate informed credit decision making. Without this information, consumers would be... From the Federal Register Online via the Government Publishing Office BUREAU OF CONSUMER FINANCIAL PROTECTION Submission for OMB Review; Comment Request AGENCY: Bureau of Consumer Financial Protection....

  12. [SDC submission to the Welsh Assembly] [f]ood consultation

    OpenAIRE

    Sustainable Development Commission Wales

    2010-01-01

    The final report of the consultation is entitled 'Food for Wales, food from Wales'. English language version of 'Ymgynghoriad ar fwyd'. Sustainable Development Commission Wales submission to the consultation on a food strategy for Wales. Publisher PDF

  13. 77 FR 9202 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-02-16

    ...; label and specification submission, 30 minutes; HACCP plan, 60 hours; recordkeeping requirements related... Sciences, known as Hazard Analysis Critical Control Point (HACCP). The information collection requirements... HACCP-based Inspection Systems,'' from the NMFS Fishery Products Inspection Manual, describes in...

  14. Electronic ways for the submission of fiscal declarations

    OpenAIRE

    Mihai ANTONESCU; Buziernescu, Radu

    2009-01-01

    The unprecedented development of information technology in the past few years has made possible the transmission of information, inclusively fiscal information, by electronic means of transmission at distance. Tax payers can use the method of submission of fiscal declarations by electronic means of transmission at distance as alternative method of deposition of fiscal declarations. For the submission of fiscal declarations by electronic means of transmission at distance, tax payers should use...

  15. Limit-Order Submission Strategies under Asymmetric Information

    OpenAIRE

    Menkhoff, Lukas; Osler, Carol Lee; Schmeling, Maik

    2010-01-01

    This paper provides evidence that informed traders dominate the response of limit-order submissions to shocks in a pure limit-order market. In the market we study, informed traders are highly sensitive to spreads, volatility, momentum and depth. By contrast, uninformed traders are relatively insensitive to all these market conditions. The dominance of the informed over limit-order submissions is magnified by contrasts between them and the uninformed in the use of aggressively-priced limit ord...

  16. Managing the Risks that Appear throughout the Pursuit of Clearing

    OpenAIRE

    Lucean MIHALCEA

    2012-01-01

    This paper proposes to deal with some aspects of clearing houses and the significant changes in European legislation in this field. It will also embark upon discussing the risks incurred in clearing houses in the current context of the international economic crisis-driven and how clearing houses in Romania can manage these risks mainly related to the market risk, credit risk and liquidity risk. This study will conclude with an econometric model of credit risk management that affects clearing ...

  17. Diagnosis of Thymic Clear Cell Carcinoma by Cytology

    OpenAIRE

    Lale, Seema A.; Tiscornia-Wasserman, Patricia G.; Mohamed Aziz

    2013-01-01

    Clear cell carcinoma of the thymus is a rare tumor. Few cases of clear-cell carcinoma of thymus have been documented (Truong et al., 1990 and Wolfe III et al., 1983). All these cases were diagnosed by histopathological examination of the tissue. Diagnosis of thymic clear cell carcinoma on cytology is extremely challenging. Here we report the first case of thymic clear cell carcinoma diagnosed by cytological examination of the pericardial fluid with the help of immunocytochemistry. Differentia...

  18. Clear cell mammary malignant myoepithelioma with abundant glycogens.

    OpenAIRE

    Kuwabara, H.; Uda, H

    1997-01-01

    Malignant myoepithelioma (myoepithelial carcinoma) of the breast is extremely rare. A case is reported of a 46 year old female with clear cell mammary malignant myoepithelioma that, on histological examination, was glycogen abundant clear cell carcinoma. Immunohistochemically, the clear cells showed myoepithelial differentiation--that is, they were a smooth muscle actin and S100 protein positive. This case shows that glycogen abundant clear cell carcinoma is a variant of malignant myoepitheli...

  19. 78 FR 105 - Proposed Collection; Comment Request (60-Day FRN); A Generic Submission for Formative Research...

    Science.gov (United States)

    2013-01-02

    ... that customers are satisfied with programs. This customer satisfaction research helps ensure the... Generic Submission for Formative Research, Pretesting, and Customer Satisfaction of NCI's Communication... Submission For Formative Research, Pretesting, and Customer Satisfaction of NCI's Communication and...

  20. Toxic Substances Control Act Test Submissions 2.0 (TSCATS 2.0)

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxic Substances Control Act Test Submissions 2.0 (TSCATS 2.0) tracks the submissions of health and safety data submitted to the EPA either as required or...

  1. 78 FR 20329 - Submission for OMB review; 30-day Comment Request: A Generic Submission for Formative Research...

    Science.gov (United States)

    2013-04-04

    ... Generic Submission for Formative Research, Pretesting, and Customer Satisfaction of NCI's Communication..., and Customer Satisfaction of NCI's Communication and Education Resources, 0925-0046, Expiration Date 2... customers are satisfied with programs. This customer satisfaction research helps ensure the...

  2. 78 FR 14558 - Submission for OMB Review; 30-Day Comment Request: A Generic Submission for Formative Research...

    Science.gov (United States)

    2013-03-06

    ... Generic Submission for Formative Research, Pretesting, and Customer Satisfaction of NCI's Communication..., Pretesting, and Customer Satisfaction of NCI's Communication and Education Resources, 0925-0046, Expiration... customers are satisfied with programs. This customer satisfaction research helps ensure the...

  3. Glycogen Rich Clear Cell Breast Carcinoma: A Case Report

    OpenAIRE

    Çınkır, Havva Yeşil; Dilek, Gülay Bilir; Demirci, Ayşe; Başal, Fatma Buğdaycı; Aydın, Kübra; Demirci, Umut; Öksüzoğlu, Berna; Alkış, Necati

    2014-01-01

    Glycogen-rich clear cell carcinoma of the breast is a rare type of breast carcinoma. Tumoral tissue is consist of intracytoplasmic glycogen-rich clear cells. We presented in here a 44-year old woman diagnosed with glycogen-rich clear cell carcinoma.

  4. Analysis of marine stratocumulus clearing events during FIRE

    Science.gov (United States)

    Kloesel, Kevin A.

    1990-01-01

    During FIRE, three major stratocumulus clearing events took place over the project region. These clearing events are analyzed using synoptic variables to determine if these clearing events can be predicted by current modeling techniques. A preliminary statistical evaluation of the correlation between satellite cloud brightness parameters and NMC global model parameters is available in Wylie, et al., 1989.

  5. 75 FR 63113 - Financial Resources Requirements for Derivatives Clearing Organizations

    Science.gov (United States)

    2010-10-14

    ... number of small entities. \\17\\ 5 U.S.C. 601 et seq. \\18\\ 47 FR 18618 (Apr. 30, 1982). \\19\\ See 66 FR..., and statement of cash flows, of the derivatives clearing organization or of its parent company; and... membership organization. Clearing members include futures commission merchants (FCMs) that clear on behalf...

  6. 75 FR 22609 - Agency Information Collection Activities; Proposals, Submissions, and Approvals: CIS Ombudsman...

    Science.gov (United States)

    2010-04-29

    ... Problem Submission Worksheet. OMB Number: 1601-0004. Frequency: One Time Response. Affected Public... Case Problem Submission Worksheet, DHS Form 7001 and Virtual Ombudsman System AGENCY: Office of the... through DHS Form 7001, Case Problem Submission Worksheet and Supporting Statement Case Problem...

  7. 37 CFR 1.417 - Submission of translation of international publication.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Submission of translation of... Provisions General Information § 1.417 Submission of translation of international publication. The submission of an English language translation of the publication of an international application pursuant to...

  8. 47 CFR 65.104 - Page limitations for rate of return submissions.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Page limitations for rate of return submissions... SERVICES (CONTINUED) INTERSTATE RATE OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Procedures § 65.104 Page limitations for rate of return submissions. Rate of return submissions, including...

  9. 48 CFR 1814.302 - Bid submission. (NASA supplements paragraph (b))

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Bid submission. (NASA supplements paragraph (b)) 1814.302 Section 1814.302 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Submission of Bids 1814.302 Bid submission. (NASA...

  10. 48 CFR 2452.232-70 - Payment schedule and invoice submission (fixed-price).

    Science.gov (United States)

    2010-10-01

    ... invoice submission (fixed-price). 2452.232-70 Section 2452.232-70 Federal Acquisition Regulations System... Texts of Provisions and Clauses 2452.232-70 Payment schedule and invoice submission (fixed-price). As... solicitations and contracts: Payment Schedule and Invoice Submission (Fixed-Price) (FEB 2006) (a)...

  11. Fall Meeting abstract submission inspires science poetry

    Science.gov (United States)

    Balcerak, Ernie

    2011-08-01

    When the 4 August deadline for submitting Fall Meeting abstracts passed, AGU had received more than 20,000 abstracts, a record-breaking number. The submission process had an unexpected by-product: It inspired some scientists to write haiku on Twitter. (Haiku is a form of Japanese poetry typically having three lines, the first with five syllables, the second with seven, and the third with five.) The following are examples of the haiku tweets, with the hashtag #AGU11AbstractHaiku. (For those who want to keep updated about the Fall Meeting on Twitter, the hashtag is #AGU11.) For more information about the meeting, including registration and housing, visit http://sites.agu.org/fallmeeting/.

  12. European Strategy Preparatory Group - CALL FOR SUBMISSIONS

    CERN Multimedia

    2012-01-01

    As part of the Update of the European Strategy for Particle Physics, the European Strategy Preparatory Group (ESPG) welcomes submissions on issues related to the strategy from individual physicists, from groups of scientists representing a community (an experiment, a topic of theoretical research, etc.) as well as from Institutions and Organizations (funding agencies, ministries, etc).   These contributions will be discussed at the meetings of the Preparatory Group and during the Open Symposium to be held on 10-12 September 2012 in Cracow, and will be made available to the Strategy Group for drafting the Update of the Strategy. How to submit a contribution? Send your contribution on the scientific issues below using the form under http://indico.cern.ch/event/espg_input (preferably as an attached PDF file): - Accelerator Physics - Astroparticle Physics, Gravitation and Cosmology - Flavour Physics and Symmetries - Physics at High Energy Frontier - Physics of Neutrinos - Strong Interaction Physics...

  13. Using sandpaper for noninvasive transepidermal optical skin clearing agent delivery

    Science.gov (United States)

    Stumpp, O.; Chen, Bo; Welch, Ashley J.

    2006-07-01

    We present a gentle mechanical method for the noninvasive transepidermal delivery of topically applied optical skin clearing agents. Optical skin clearing reduces light scattering in highly turbid skin with the aid of hyperosmotic chemicals such as glycerol, polyethylene glycol, and solutions of dextrose. Transepidermal delivery of such agents is believed to be most patient compliant and most likely to be used in a clinical environment. Optical skin clearing has the potential to expand the current limited use of laser light in medicine for diagnostic and therapeutic applications. Light scattering limits the penetration depth of collimated light into skin. In order to increase the diffusion of topically applied optical skin clearing agents into skin, we present a gentle mechanical delivery method involving glycerol and dextrose as optical skin clearing agents and fine 220-grit sandpaper to rub the clearing agent into the tissue. Gentle rubbing causes abrasion of the superficial skin layer including the stratum corneum, which otherwise prevents these optical skin clearing agents from freely diffusing into skin. Results indicate very fast optical skin clearing rates. In vivo hamster skin turned transparent within 2 min. The 1/e light penetration depth increased by 36+/-3.75% for dextrose and 43+/-8.24% for glycerol. Optical skin clearing was reversed using phosphate buffered saline solution. Skin viability was observed 70 h post-treatment and showed scabbing and erythema on a few percent of the total optically cleared skin surface.

  14. Global ballast water management and the "same location" concept: a clear term or a clear issue?

    Science.gov (United States)

    David, Matej; Gollasch, Stephan; Pavliha, Marko

    2013-03-01

    The United Nations recognized the transfer of harmful organisms and pathogens across natural barriers as one of the four greatest pressures to the world's oceans and seas, causing global environmental changes, while also posing a threat to human health, property, and resources. Ballast water transferred by vessels was recognized as a prominent vector of such species and was regulated by the International Convention for the Control and Management of Ship's Ballast Water and Sediments (2004). Permanent exceptions from ballast water management requirements may apply when the uptake and discharge of ballast water occur at the "same location." However, the "same location" concept may be interpreted differently, e.g., a port basin, a port, an anchorage, or a larger area even with more ports inside. Considering that the Convention is nearing the beginning of enforcement, national authorities all around the world will soon be exposed to applications for exceptions. Here we consider possible effects of different interpretations of the "same location" concept. We have considered different possible extensions of the same location through environmental, shipping, and legal aspects. The extension of such areas, and the inclusion of more ports, may compromise the Convention's main purpose. We recommend that "same location" mean the smallest practicable unit, i.e., the same harbor, mooring, or anchorage. An entire smaller port, possibly also including the anchorage, could be considered as same location. For larger ports with a gradient of environmental conditions, "same location" should mean a terminal or a port basin. We further recommend that IMO consider the preparation of a guidance document to include concepts, criteria, and processes outlining how to identify "same location," which limits should be clearly identified. PMID:23634585

  15. 17 CFR 40.2 - Listing and accepting products for trading or clearing by certification.

    Science.gov (United States)

    2010-04-01

    ..., a designated contract market or a registered derivatives transaction execution facility must comply... that is not traded on a designated contract market, derivatives transaction execution facility or.... A submission shall comply with the following conditions: (1) The designated contract market...

  16. Optimized optical clearing method for imaging central nervous system

    Science.gov (United States)

    Yu, Tingting; Qi, Yisong; Gong, Hui; Luo, Qingming; Zhu, Dan

    2015-03-01

    The development of various optical clearing methods provides a great potential for imaging entire central nervous system by combining with multiple-labelling and microscopic imaging techniques. These methods had made certain clearing contributions with respective weaknesses, including tissue deformation, fluorescence quenching, execution complexity and antibody penetration limitation that makes immunostaining of tissue blocks difficult. The passive clarity technique (PACT) bypasses those problems and clears the samples with simple implementation, excellent transparency with fine fluorescence retention, but the passive tissue clearing method needs too long time. In this study, we not only accelerate the clearing speed of brain blocks but also preserve GFP fluorescence well by screening an optimal clearing temperature. The selection of proper temperature will make PACT more applicable, which evidently broaden the application range of this method.

  17. 76 FR 44935 - Draft Guidance for Industry and Food and Drug Administration Staff; 510(k) Device Modifications...

    Science.gov (United States)

    2011-07-27

    ... the Utilization of Science in Regulatory Decision Making Preliminary Report and Recommendations... Manufacturers, International, and Consumer Assistance, Center for Devices and Radiological Health, Food and Drug... legally marketed device. This draft guidance is not final nor is it in effect at this time....

  18. 76 FR 81510 - Draft Guidance for Industry and Food and Drug Administration Staff; the 510(k) Program...

    Science.gov (United States)

    2011-12-28

    ... Communication, Outreach and Development (HFM-40), Center for Biologics Evaluation and Research (CBER), Food and...) Paradigm Guidance. FDA recognizes and supports efforts for global convergence of regulatory systems, and...

  19. Current treatment approach to non-clear cell renal carcinoma

    OpenAIRE

    I. V. Tsimafeyeu

    2015-01-01

    Non-clear cell renal cell carcinoma has various histologic subtypes. Tumor biology plays significant role in the disease development. However, despite the one surgical approach both to clear cell and non-clear cell renal carcinoma, patients’ outcomes within one stage of the disease may vary. Furthermore, tumor sensitivity and its response to therapy are highly dependent on the same histologic subtype.The article gives detailed data on the current treatment of papillary, chromophobe and other ...

  20. The Clearing: Heidegger’s Lichtung and The Big Scrub

    Directory of Open Access Journals (Sweden)

    Rob Garbutt

    2010-02-01

    Full Text Available Clearings make settlement possible. Whether on a small scale using an axe and other hand implements to make way for a dwelling and a garden, or on a large scale with a chain strung between two D9 bulldozers in preparation for a major agribusiness development, the process of clearing creates spaces for installing something new. This paper uses the idea of (the clearing, as practice, process, outcome and metaphor, to examine the installation of the locals in a settler society. Using Lismore on the far-north coast of New South Wales, Australia, as a case example, the particular work of clearing that is discussed here is a practice that enables a form of colonisation and settlement that distances itself from its history of migration. This is a history of settler locals who were 'always here', and a colonial form of clearing clears the land and the mind of troubling pasts and of troubling presences. For the locals within a place, then, clearing manages and simplifies a complex set of social and material relations, histories and identities. Using Anthony Appiah's concept the 'space clearing gesture', the paper concludes with a reflection on the space in which the idea of "the clearing" and this paper appears. Do places, in this instance rural places, provide a type of clearing in which certain ideas might appear that may not appear elsewhere? If situatedness matters then the diversity of places where thinking is done is important for our ecology of thought, and in connection with this, perhaps what 'rural cultural studies' does is clear a particular type of space for thinking.

  1. The Clearing : Heidegger’s Lichtung and the big scrub

    Directory of Open Access Journals (Sweden)

    Garbutt, Rob

    2010-01-01

    Full Text Available Clearings make settlement possible. Whether on a small scale using an axe and other hand implements to make way for a dwelling and a garden, or on a large scale with a chain strung between two D9 bulldozers in preparation for a major agribusiness development, the process of clearing creates spaces for installing something new. This paper uses the idea of (the clearing, as practice, process, outcome and metaphor, to examine the installation of the locals in a settler society. Using Lismore on the far-north coast of New South Wales, Australia, as a case example, the particular work of clearing that is discussed here is a practice that enables a form of colonisation and settlement that distances itself from its history of migration. This is a history of settler locals who were 'always here', and a colonial form of clearing clears the land and the mind of troubling pasts and of troubling presences. For the locals within a place, then, clearing manages and simplifies a complex set of social and material relations, histories and identities.Using Anthony Appiah's concept the 'space clearing gesture', the paper concludes with a reflection on the space in which the idea of "the clearing" and this paper appears. Do places, in this instance rural places, provide a type of clearing in which certain ideas might appear that may not appear elsewhere? If situatedness matters then the diversity of places where thinking is done is important for our ecology of thought, and in connection with this, perhaps what 'rural cultural studies' does is clear a particular type of space for thinking.

  2. Close but not a central bank: The New York Clearing House and issues of clearing house loan certificates

    OpenAIRE

    Jon R. Moen; Ellis W. Tallman

    2013-01-01

    The paper examines the New York Clearing House (NYCH) as a lender of last resort by looking at clearing-house-loan-certificate borrowing during five banking panics of the National Banking Era (1863–1913). In that system, adequate aggregate liquidity provision was passive and dependent upon member bank borrowing. We document bank borrowing behavior using bank-level data for clearing-house loan certifi cates issued to NYCH member banks. The historical record reveals that the large New York City...

  3. Validation of the McClear clear-sky model in desert conditions with three stations in Israel

    OpenAIRE

    Lefèvre, Mireille; Wald, Lucien

    2016-01-01

    The new McClear clear-sky model, a fast model based on a radiative transfer solver, exploits the atmospheric properties provided by the EU-funded Copernicus Atmosphere Monitoring Service (CAMS) to estimate the solar direct and global irradiances received at ground level in cloud-free conditions at any place any time. The work presented here focuses on desert conditions and compares the McClear irradiances to coincident 1 min measurements made in clear-sky conditions at three...

  4. Multigate and fast clear logic in FERA readout

    International Nuclear Information System (INIS)

    The operation of CAMAC FERA readout with several sources of Gate and Clear signals in the same branch is described including fast Clear before completion of the digitization or the data transfer. Different FERA compatible modules are used within the branch. The presented logic is implemented in the DIRAC experiment with four FERA branches

  5. Breast metastasis from clear cell renal cell carcinoma

    OpenAIRE

    Botticelli, A.; De Francesco, G. P.; D. Di Stefano

    2013-01-01

    In Western countries, breast cancer is the most common cancer in women, whereas metastases to the breast from extramammary malignancies are extremely rare. We present the case of a 60-year-old woman, who underwent surgery in 2007 for clear cell renal cell carcinoma and who 4 years later presented with a breast metastasis from clear cell renal cell carcinoma.

  6. The Nordic power market: Are there alternatives to expensive clearing?

    International Nuclear Information System (INIS)

    The Enron scandal of 2002 has set focus on counter party risk in the Nordic power market and is an important cause of increased clearing of bilateral financial power contracts. The article discusses whether expensive clearing is always the best tool for dealing with counter party risk

  7. 76 FR 16587 - Risk Management Requirements for Derivatives Clearing Organizations

    Science.gov (United States)

    2011-03-24

    ...The Commodity Futures Trading Commission (Commission) is reopening the comment period for a proposed rule that would require derivatives clearing organizations (DCOs) to report end-of-day positions for each clearing member, by customer origin and house origin, and for customer origin, separately, the gross positions of each beneficial...

  8. ClearPEM: prototype PET device dedicated to breast imaging

    CERN Multimedia

    Joao Varela

    2009-01-01

    Clinical trials have begun in Portugal on a new breast imaging system (ClearPEM) using positron emission tomography (PET). The system, developed by a Portuguese consortium in collaboration with CERN and laboratories participating in the Crystal Clear collaboration, will detect even the smallest tumours and thus help avoid unnecessary biopsies.

  9. 78 FR 50259 - Derivatives Clearing Organizations and International Standards

    Science.gov (United States)

    2013-08-16

    ... addition, an FMI must clearly specify the roles and responsibilities of the board of directors and... is the Supervisory Agency only for CME and ICE Clear Credit, the SEC serves as OCC's Supervisory... ensure that the board of directors has the appropriate incentive to fulfill its multiple roles, the...

  10. A simple formula for determining globally clear skies

    Energy Technology Data Exchange (ETDEWEB)

    Long, C.N.; George, A.T.; Mace, G.G. [Penn State Univ., University Park, PA (United States)] [and others

    1996-04-01

    Surface measurements to serve as {open_quotes}ground truth{close_quotes} are of primary importance in the development of retrieval algorithms using satellite measurements to predict surface irradiance. The most basic algorithms of this type deal with clear sky (i.e., cloudless) top-to-surface shortwave (SW) transfer, serving as a necessary prerequisite towards treating both clear and cloudy conditions. Recently, atmosphere SW cloud forcing to infer the possibility of excess atmospheric absorption (compared with model results) in cloudy atmospheres. The surface component of this ratio relies on inferring the expected clear sky SW irradiance to determine the effects of clouds on the SW energy budget. Solar renewable energy applications make use of clear and cloud fraction climatologies to assess solar radiation resources. All of the above depend to some extent on the identification of globally clear sky conditions and the attendant measurements of downwelling SW irradiance.

  11. Comparison of skin optical clearing by different drug delivery method

    International Nuclear Information System (INIS)

    Previous studies have shown that optical clearing techniques have great potential for optical diagnosis and therapy. In order to further discuss the effect by different drug delivery method, diffusion chambers were used to simulate in vivo physiological environment; and the optical clearing agents were acted on the surface of porcine skin, the saline was contacted with the dermal side (epidermal application). Then they were compared with the traditional method-samples immersed in the optical clearing agents (mainly dermal immersion). The transmission intensity of skin was monitored by an integrating sphere system. The changes in thickness were measured before and after experiments. The results showed that the optical clearing effect and the changes in thickness are not coincident under the two different methods. It indicates that the optical clearing effect and mechanism may relate to the drug delivery method.

  12. Comparison of skin optical clearing by different drug delivery method

    Energy Technology Data Exchange (ETDEWEB)

    Mao, Z; Ge, X [Department of Fundamental Theories, Shandong Sports University, Jinan, 250102 (China); Li, E, E-mail: mm73@163.com [Institute of Physical Education, Huazhong Normal University, Wuhan, 430079 (China)

    2011-01-01

    Previous studies have shown that optical clearing techniques have great potential for optical diagnosis and therapy. In order to further discuss the effect by different drug delivery method, diffusion chambers were used to simulate in vivo physiological environment; and the optical clearing agents were acted on the surface of porcine skin, the saline was contacted with the dermal side (epidermal application). Then they were compared with the traditional method-samples immersed in the optical clearing agents (mainly dermal immersion). The transmission intensity of skin was monitored by an integrating sphere system. The changes in thickness were measured before and after experiments. The results showed that the optical clearing effect and the changes in thickness are not coincident under the two different methods. It indicates that the optical clearing effect and mechanism may relate to the drug delivery method.

  13. Clear cell hepatocellular carcinoma: Back to the basics for diagnosis

    Directory of Open Access Journals (Sweden)

    Puja Sakhuja

    2015-01-01

    Full Text Available Hepatocellular carcinoma (HCC is a common cancer world-wide with a higher incidence in Asia. Clear cell variant of HCC (CCHCC has a frequency ranging from 0.4% to 37%. The presence of 90-100% clear cells is rare. In the present case, a 35-year-old female patient presented with fever and a large abdominal mass in the right hypochondrium. Histology of the tumor revealed >95% clear cells and after taking multiple sections from different areas of tumor only few scattered cells with eosinophilic cytoplasm were found. Immunohistochemistry with Hep Par 1, Glypican 3 and polyclonal carcinoembryonic antigen were negative as were all other markers for metastatic clear cell tumors. Histological diagnosis was based on routine H and E sections showing a histological pattern of architecture with thickened trabeculae. We describe a rare case of CCHCC with >95% clear cells and no immunoreactivity in tumor cells in a non-cirrhotic liver.

  14. 75 FR 27338 - NASDAQ OMX Commodities Clearing-Contract Merchant LLC; NASDAQ OMX Commodities Clearing-Delivery...

    Science.gov (United States)

    2010-05-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission NASDAQ OMX Commodities Clearing--Contract Merchant LLC; NASDAQ OMX.... Take notice that, on May 3, 2010, NASDAQ OMX Commodities Clearing-- Contract Merchant LLC, NASDAQ...

  15. Author Guidelines - Standards for Submission Diretrizes para Autores - Normas de Submissão

    Directory of Open Access Journals (Sweden)

    Revista Brasileira de Medicina de Família e Comunidade RBMFC

    2011-09-01

    Full Text Available

    Purpose and Editorial Policy

    The peer review process

    Sections and Types of Articles

    Presentation and Preparation of Manuscripts

    Electronic Submissions

    Statement of authorship

    Sample Statement of Authorship and Responsibility

    Research ethics

    Acknowledgments

    Additional doubts and clarification

    Objetivo e Política Editorial

    Processo de avaliação pelos pares

    Seções e Tipos de Trabalhos

    Apresentação e Preparo dos Manuscritos

    Submissão Eletrônica

    Declaração de Autoria e responsabilidade dos autores

    Exemplo de Declaração de Autoria e Responsabilidade

    Ética em Pesquisa

    Agradecimentos

    Dúvidas e Esclarecimentos adicionais

  16. Molecular Characterization of Clear Cell Lesions of Head and Neck.

    Science.gov (United States)

    Jain, Anshi; Shetty, Devi Charan; Juneja, Saurabh; Narwal, Nidhi

    2016-05-01

    The salivary glands, oral mucosa and jaws constitute a group of lesions which are heterogeneous in nature and are odontogenic, salivary or metastatic in origin. This group of tumours is termed as Clear Cell Tumours. Fixation artifacts are one of the most important reasons for the cell to appear clear but clearing of cells may also result from cytoplasmic accumulation of water, presence of glycogen within the cell, intermediate filaments, immature zymogen granules, or a paucity of cellular organelles. Clear cell Odontogenic neoplasms predominantly include odontogenic carcinoma, ameloblastoma and calcifying epithelial odontogenic tumour. Clear cell tumours of salivary gland origin are almost invariably malignant in nature but they do include two benign lesions. Very frequently, surgical pathologist encounters clear cells in many malignant neoplasms, the nature and sources of which are undetermined on the basis of conventional histopathology. This review will selectively discuss the clinicopathological features of neoplasms which at times may pose a diagnostic challenge and dilemma due to clear cell changes. PMID:27437379

  17. An experimental investigation of loop seal clearings in SBLOCA tests

    International Nuclear Information System (INIS)

    Highlights: • An experimental study of the loop seal clearing in the SBLOCAs was performed. • Loop seal behaviors with related parameters were investigated. • The mechanism of initiation of a loop seal clearing was suggested. • The sustaining of a loop seal clearing without refilling was evaluated. - Abstract: An investigation of the loop seal clearing (LSC) in a small-break loss-of-coolant accident (SBLOCA) for direct vessel injection (DVI) line and cold leg (CL) breaks was performed. The behavior of an LSC appears to be closely related to the break location and break size. In the tests of SBLOCAs, a loop seal or cross-over leg (COL) in the broken loop was cleared first, and the number of loop seals cleared was dependent on the break size. The larger the break size was, the more the loop seals or COLs that were cleared. The location of the LSCs appeared to have a consistent behavior under each scenario. In the SBLOCA tests, the downcomer water level just before an LSC was a very important parameter to the peak cladding temperature (PCT). The initiation of an LSC might not be related to the existing flooding condition, but to the magnitude of the pressure difference between the reactor upper head and downcomer, which is sufficient to push the upflow leg of a COL. The sustaining of an LSC without refilling was evaluated using the test data and existing flooding conditions

  18. REMINDER : deadline for submission of reimbursements claims to UNIQA

    CERN Multimedia

    HR Department

    2011-01-01

    We would like to remind you of the resolution which took effect from 1 June 2010 changing the deadline for submitting a claim from 24 months to 12 months from the invoice date (as opposed to from the time of treatment). As a transitional measure, it is still possible to submit invoices issued prior to 1 June 2010 as long as they do not date back to more than two years (from the invoice date) at the time of submission. The deadline for transitional claims is 31 May 2011. You are advised to check any outstanding submissions that you have since, as from 1 June 2011, no transitional claims will be accepted.  

  19. A Comparison of Parameter Study Creation and Job Submission Tools

    Science.gov (United States)

    DeVivo, Adrian; Yarrow, Maurice; McCann, Karen M.; Biegel, Bryan (Technical Monitor)

    2001-01-01

    We consider the differences between the available general purpose parameter study and job submission tools. These tools necessarily share many features, but frequently with differences in the way they are designed and implemented For this class of features, we will only briefly outline the essential differences. However we will focus on the unique features which distinguish the ILab parameter study and job submission tool from other packages, and which make the ILab tool easier and more suitable for use in our research and engineering environment.

  20. Clear-PEM, a dedicated PET camera for mammography

    CERN Document Server

    Lecoq, P

    2002-01-01

    Preliminary results suggest that Positron Emission Mammography (PEM) can offer a noninvasive method for the diagnosis of breast cancer. Metabolic images from PEM contain unique information not available from conventional morphologic imaging techniques and aid in expeditiously establishing the diagnosis of cancer. A dedicated machine seems to offer better perspectives in terms of position resolution and sensitivity. This paper describes the concept of Clear-PEM, the system presently developed by the Crystal Clear Collaboration at CERN for an evaluation of this approach. This device is based on new crystals introduced by the Crystal Clear as well as on modern data acquisition techniques developed for the large experiments in high energy physics experiments.

  1. Clearing and Labeling Techniques for Large-Scale Biological Tissues.

    Science.gov (United States)

    Seo, Jinyoung; Choe, Minjin; Kim, Sung-Yon

    2016-06-30

    Clearing and labeling techniques for large-scale biological tissues enable simultaneous extraction of molecular and structural information with minimal disassembly of the sample, facilitating the integration of molecular, cellular and systems biology across different scales. Recent years have witnessed an explosive increase in the number of such methods and their applications, reflecting heightened interest in organ-wide clearing and labeling across many fields of biology and medicine. In this review, we provide an overview and comparison of existing clearing and labeling techniques and discuss challenges and opportunities in the investigations of large-scale biological systems. PMID:27239813

  2. Reconstruction of Clear-PEM data with STIR

    CERN Document Server

    Martins, M V; Rodrigues, P; Trindade, A; Oliveira, N; Correia, M; Cordeiro, H; Ferreira, N C; Varela, J; Almeida, P

    2006-01-01

    The Clear-PEM scanner is a device based on planar detectors that is currently under development within the Crystal Clear Collaboration, at CERN. The basis for 3D image reconstruction in Clear-PEM is the software for tomographic image reconstruction (STIR). STIR is an open source object-oriented library that efficiently deals with the 3D positron emission tomography data sets. This library was originally designed for the traditional cylindrical scanners. In order to make its use compatible with planar scanner data, new functionalities were introduced into the library's framework. In this work, Monte Carlo simulations of the Clear-PEM scanner acquisitions were used as input for image reconstruction with the 3D OSEM algorithm available in STIR. The results presented indicate that dual plate PEM data can be accurately reconstructed using the enhanced STIR framework.

  3. Impact of Ion Clearing Electrodes on Beam Dynamics in DAFNE

    CERN Document Server

    Zobov, M; Clozza, A; Lollo, V; Milardi, C; Spataro, B; Stella, A; Vaccarezza, C

    2007-01-01

    Presently clearing electrodes are being considered as a possible cure of e-cloud driven problems in existing and future colliders. 'Invisible' electrodes, made of a thin highly resistive layer pasted on a dielectric plate, have been proposed as one of design solutions for the e-cloud clearing. For the first time such electrodes were successfully used in the electron-positron accumulator (EPA) of LEP. Similar electrodes had been using for a long time for ion clearing purposes in the DAFNE electron ring. Theoretical considerations and experimental measurements at DAFNE have revealed a substantial contribution of the ion clearing electrodes (ICE) to the machine broad-band impedance giving rise to several harmful effects degrading the collider performance. In this paper we discuss the impact of the electrodes on DAFNE beam dynamics, show the results of ICE wake field and impedance calculations and compare them with available experimental data. We also describe the procedure of ICE removal from the wiggler section...

  4. CBFS: high performance feature selection algorithm based on feature clearness.

    Directory of Open Access Journals (Sweden)

    Minseok Seo

    Full Text Available BACKGROUND: The goal of feature selection is to select useful features and simultaneously exclude garbage features from a given dataset for classification purposes. This is expected to bring reduction of processing time and improvement of classification accuracy. METHODOLOGY: In this study, we devised a new feature selection algorithm (CBFS based on clearness of features. Feature clearness expresses separability among classes in a feature. Highly clear features contribute towards obtaining high classification accuracy. CScore is a measure to score clearness of each feature and is based on clustered samples to centroid of classes in a feature. We also suggest combining CBFS and other algorithms to improve classification accuracy. CONCLUSIONS/SIGNIFICANCE: From the experiment we confirm that CBFS is more excellent than up-to-date feature selection algorithms including FeaLect. CBFS can be applied to microarray gene selection, text categorization, and image classification.

  5. Molecular Air Data Clear Air Turbulence Sensor: MADCAT Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Clear air turbulence (CAT), often referred to as "air pockets," is attributed to Kelvin-Helmholtz instabilities at altitudes usually above 18,000ft, often without...

  6. Molecular Air Data Clear Air Turbulence Sensor: MADCAT Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Clear air turbulence (CAT), often referred to as "air pockets," is attributed to Kelvin-Helmholtz instabilities at altitudes generally above 18,000ft, often in the...

  7. CLEAR CELL MYOEPITHELIAL CARCINOMA OF OROPHARYNX : A CASE REPORT

    OpenAIRE

    Adil; Nataraju; Ravi Kuma

    2012-01-01

    ABSTRACT: Myoepitheliomas are rare neoplasms. We present a case of clear cell myoepithelial carcinoma arising from submucosal minor salivary gl ands of oropharynx.The significance of this lesion is that it is a recent entity 1,2 and it shares morphological similarities with many neoplasms that pose a challenge in the diagnosis. It has to be distinguished from benign myoepitheliom as and neoplasms with predominantly clear cells...

  8. Transformation of Abdominal Wall Endometriosis to Clear Cell Carcinoma

    OpenAIRE

    Maria Paula Ruiz; Darryl Lewis Wallace; Matthew Thomas Connell

    2015-01-01

    Clear cell carcinoma is the least common of the malignant transformations reported in nonpelvic sites of endometriosis. Two cases with clear cell carcinoma transformation arising from endometriosis in abdominal wall scars are presented. These patients underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy, pelvic washings, and abdominal wall lesion resection. The first case had initial treatment with chemotherapy, while chemotherapy and radiation therapy were given for th...

  9. Clinical enigma: A rare case of clear cell odontogenic carcinoma

    OpenAIRE

    Cheshta Walia; Rudra Prasad Chatterjee; Sanchita Kundu; Sudip Roy

    2015-01-01

    Clear cell odontogenic carcinoma is a rare, aggressive neoplasm of the jaw with only 74 reported cases. It occurs predominantly in the mandibular anterior region during fifth to seventh decades of life. Clinically it manifests as intra-bony swelling with a variable degree of pain. Microscopically, it reveals nests of cells with clear cytoplasm in connective tissue stroma arranged in different patterns. It is often misdiagnosed due to the rarity of lesion and confusing histopathology. Immunohi...

  10. Rare tumors of the gallbladder: Clear cell carcinoma

    OpenAIRE

    Huseyin Eken; Mecdi Gurhan Balci; Sercan Buyukakincak; Arda Isik; Deniz Firat; Orhan Cimen

    2015-01-01

    Introduction: Gallbladder cancer is a rare tumor in the gastrointestinal tract has poor prognosis, low survival and is difficult to diagnose. The most common type of gallbladder cancer is adenocarcinoma, and the incidence of clear cell carcinoma is low. Mostly, it is difficult to determine whether the isolated tumor is a primary tumor in the gallbladder or a metastatic tumor from another region. Before accepting a clear cell carcinoma as a primary gallbladder tumor, the kidneys and other poss...

  11. Clearing Barter Exchange Markets: Kidney Exchange and Beyond

    OpenAIRE

    Glorie, Kristiaan

    2014-01-01

    markdownabstract__Abstract__ Advanced computer assisted markets, otherwise known as smart markets, are becoming an important part of our modern society. This dissertation considers smart barter exchange markets, which enable people to trade a wide range of goods: from shifts, to houses, to kidneys. Centralized and computerized clearing is what makes these markets ‘smart’. The market clearing problem is to match demand and supply so as to maximize the gains of trade. Trades, in this regard, ne...

  12. Clearing of the sea bed in the North Sea 1993

    International Nuclear Information System (INIS)

    The report relates to an NPD (Norwegian Petroleum Directorate) project which aimed to clear away objects from the sea bed on the Norwegian continental shelf. The project was divided in two phases. Phase 1 included the recording of objects by the use of sonars, and phase 2 covered the clearing operation itself. The results from the project, which included a fishery-intensive and oil-related area of 1300 km2 on Egersundbanken, are presented. 3 figs., 4 tabs

  13. Arbitraging Margins - do Clearing Houses oddly assess position risks?

    OpenAIRE

    Zambruno, G

    2008-01-01

    Margins called by Clearing Houses whenever a new position is opened are often deemed to be good indicators of the riskiness of the position. This approach complies with IOSCO recommendation to maintain sufficient financial resources to withstand, at a minimum, a default by the participant to which it has the largest exposure in extreme but plausible market conditions. This statement clearly indicates that initial margins should account for the position's riskiness in a way similar to the Valu...

  14. Global horizontal irradiance clear sky models : implementation and analysis.

    Energy Technology Data Exchange (ETDEWEB)

    Stein, Joshua S.; Hansen, Clifford W.; Reno, Matthew J.

    2012-03-01

    Clear sky models estimate the terrestrial solar radiation under a cloudless sky as a function of the solar elevation angle, site altitude, aerosol concentration, water vapor, and various atmospheric conditions. This report provides an overview of a number of global horizontal irradiance (GHI) clear sky models from very simple to complex. Validation of clear-sky models requires comparison of model results to measured irradiance during clear-sky periods. To facilitate validation, we present a new algorithm for automatically identifying clear-sky periods in a time series of GHI measurements. We evaluate the performance of selected clear-sky models using measured data from 30 different sites, totaling about 300 site-years of data. We analyze the variation of these errors across time and location. In terms of error averaged over all locations and times, we found that complex models that correctly account for all the atmospheric parameters are slightly more accurate than other models, but, primarily at low elevations, comparable accuracy can be obtained from some simpler models. However, simpler models often exhibit errors that vary with time of day and season, whereas the errors for complex models vary less over time.

  15. Enhancement of optical skin clearing efficacy using a microneedle roller

    Science.gov (United States)

    Yoon, Jinhee; Son, Taeyoon; Choi, Eung-ho; Choi, Bernard; Nelson, J. Stuart; Jung, Byungjo

    2009-01-01

    Light scattering in biological tissues can be reduced by using optical clearing agents. Various physical methods in conjunction with agents have been studied to enhance the optical clearing efficacy of skin for diagnostic and therapeutic applications. In this study, we propose a new physical method to enhance the optical clearing potential of topically applied glycerol. A microneedle roller is used to easily create numerous transdermal microchannels prior to glycerol application. The optical clearing efficacy of skin is quantitatively evaluated with the use of a modulation transfer function target placed underneath ex vivo porcine skin samples. From cross-polarized images acquired at various time points after glycerol application, we find that samples treated with the microneedle roller resulted in an approximately two-fold increase in contrast compared to control samples 30 min after glycerol application. In conclusion, our data suggest that the microneedle roller can be a good physical method to enhance transdermal delivery of optical clearing agents, and hence their optical clearing potential over large regions of skin. PMID:18465952

  16. Coastal sediment elevation change following anthropogenic mangrove clearing

    Science.gov (United States)

    Hayden, Heather L.; Granek, Elise F.

    2015-11-01

    Coastal mangrove forests along tropical shorelines serve as an important interface between land and sea. They provide a physical buffer protecting the coastline from erosion and act as sediment "traps" catching terrestrial sediment, thus preventing smothering of subtidal coral reefs. Coastal development that removes mangrove habitat may impact adjacent nearshore coral reefs through sedimentation and nutrient loading. We examined differences in sediment elevation change between patches of open-coast intact and anthropogenically cleared red mangroves (Rhizophora mangle) on the east side of Turneffe Atoll, Belize, to quantify changes following mangrove clearing. Samples were collected over a 24 month period at five study sites, each containing paired intact (+mangrove) and cleared (-mangrove) plots. Five sediment elevation pins were deployed in each plot: behind areas cleared of mangroves (-mangrove) and behind adjacent intact mangroves (+mangrove). Sediment elevation increased at intact mangrove sites (M = +3.83 mm, SE = 0.95) whereas cleared mangrove areas suffered elevation loss (M = -7.30 mm, SE = 3.38). Mangroves inshore of partial or continuous gaps in the adjacent fringing reefs had higher rates of elevation loss (M = -15.05 mm) than mangroves inshore of continuous fringing reefs (M = -1.90 mm). Our findings provide information on potential effects of mangrove clearing and the role of offshore habitat characteristics on coastal sediment trapping and maintenance of sediment elevation by mangroves. With implications for coastline capacity to adjust to sea level rise, these findings are relevant to management of coastal fringing mangrove forests across the Caribbean.

  17. 77 FR 38581 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-06-28

    ... Agency. Title: Online Customer Relationship Management (CRM)/Performance Databases, Online Phoenix... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management....gov . Dated: June 22, 2012. Gwellnar Banks, Management Analyst, Office of the Chief...

  18. 19 CFR 10.422 - Submission of certificate of eligibility.

    Science.gov (United States)

    2010-04-01

    ... Free Trade Agreement Tariff Preference Level § 10.422 Submission of certificate of eligibility. (a) Contents. An importer who claims preferential tariff treatment on a non-originating cotton or man-made... detailed to relate it to the invoice and the HS nomenclature; (vi) The HTSUS tariff classification of...

  19. 78 FR 47016 - Submission for Review: Request for External Review

    Science.gov (United States)

    2013-08-02

    ... March 11, 2013, 78 FR 15560, which outlined an external review process that would be available to... MANAGEMENT Submission for Review: Request for External Review AGENCY: U.S. Office of Personnel Management... on a new information collection request (ICR) 3206-NEW, Request for External Review. As required...

  20. 75 FR 20561 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-04-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... exchange carriers, facilities-based mobile telephony service providers, and wireless Internet...

  1. 77 FR 64950 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-10-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... (GPS) coordinate data from a respondent's mobile device, such as cellular phone or tablet,...

  2. 77 FR 18203 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-03-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... to the question ``Does this house, apartment or mobile home have hot and cold running...

  3. 76 FR 63281 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-10-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... public safety confidence in purchasing land mobile radio (LMR) equipment built to P25 LMR...

  4. 76 FR 55657 - Notice of Submission for OMB Review

    Science.gov (United States)

    2011-09-08

    ... Services Type of Review: Revision. Title of Collection: Annual Progress Report for the Access to Telework...: Nineteen states currently have Access to Telework programs that provide financial loans to individuals with... that is not required for submission by the Telework grantees, further reducing the burden...

  5. 76 FR 77767 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-12-14

    ... Submission for OMB Review; Comment Request December 8, 2011. The Department of Agriculture has submitted the following information collection requirement(s) to OMB for review and clearance under the Paperwork..., controlling, and eradicating diseases and pests of animal, is authorized to cooperate with foreign...

  6. 76 FR 28438 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-05-17

    ...; the National Child Abuse and Neglect Data System (NCANDS); Child Abuse Prevention and Treatment Act... to report specific information related to child abuse and neglect. CFR 1355.52 provides funding... HUMAN SERVICES Administration for Children and Families Submission for OMB Review; Comment Request...

  7. 76 FR 20356 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-04-12

    ...; the National Child Abuse and Neglect Data System (NCANDS); Child Abuse Prevention and Treatment Act... to report specific information related to child abuse and neglect. CFR 1355.52 provides funding... HUMAN SERVICES Administration for Children and Families Submission for OMB Review; Comment Request...

  8. 77 FR 39496 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-07-03

    ..., Child Abuse and Neglect Program and the Child Welfare Training Program. Grantees will submit this... 45. Performance Measurement On-Line Tool Child Abuse and Neglect 2 per fiscal year One hour per... HUMAN SERVICES Administration for Children and Families Submission for OMB Review; Comment Request...

  9. 78 FR 28006 - Submission for Review: Reemployment of Annuitants

    Science.gov (United States)

    2013-05-13

    ... MANAGEMENT Submission for Review: Reemployment of Annuitants AGENCY: U.S. Office of Personnel Management... NW., Washington, DC 20503, Attention: Desk Officer for the Office of Personnel Management or sent via..., Attention: Desk Officer for the Office of Personnel Management or sent via email to...

  10. 28 CFR 901.2 - Interpretation of fingerprint submission requirements.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Interpretation of fingerprint submission requirements. 901.2 Section 901.2 Judicial Administration NATIONAL CRIME PREVENTION AND PRIVACY COMPACT COUNCIL... identification with requests for criminal history record checks for noncriminal justice purposes. The...

  11. 75 FR 2928 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-01-19

    ...: 1513-0123. Type of Review: Extension. Title: Application, Permit, and Report--Wine and Beer (Puerto... Submission for OMB Review; Comment Request January 11, 2010. The Department of Treasury will submit the following public information collection requirement(s) to OMB for review and clearance under the...

  12. 78 FR 47749 - Submission of Questionnaire for OMB Review

    Science.gov (United States)

    2013-08-06

    ... COMMISSION Submission of Questionnaire for OMB Review AGENCY: United States International Trade Commission... request for approval of a questionnaire to the Office of Management and Budget for review. Purpose of Information Collection: The information requested by the questionnaire is for use by the Commission...

  13. 40 CFR 52.16 - Submission to Administrator.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Submission to Administrator. 52.16... Administrator. (a) All requests, reports, applications, submittals, and other communications to the Administrator pursuant to this part shall be submitted in duplicate and addressed to the appropriate...

  14. 75 FR 81976 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-12-29

    ... Patent and Trademark Office Submission for OMB Review; Comment Request The United States Patent and... (44 U.S.C. chapter 35). Agency: United States Patent and Trademark Office (USPTO). ] Title: Global... and the value of the experience as it relates to future job performance. The USPTO also uses...

  15. 13 CFR 115.30 - Submission of Surety's guarantee application.

    Science.gov (United States)

    2010-01-01

    ... days, or in the case of a bonding line, within 15 business days (see § 115.33(d)(2)) after Execution of... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Submission of Surety's guarantee application. 115.30 Section 115.30 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION SURETY...

  16. 77 FR 4373 - Submission for OMB Review; Comments Request

    Science.gov (United States)

    2012-01-27

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC... U.S.C. Chapter 35), agencies are required to publish a Notice in the Federal Register notifying...

  17. 76 FR 38220 - Submission of OMB review; comments request

    Science.gov (United States)

    2011-06-29

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission of OMB review; comments request AGENCY: Overseas Private Investment Corporation (OPIC.... Chapter 35), agencies are required to publish a Notice in the Federal Register notifying the public...

  18. 76 FR 73740 - Submission for OMB Review; Comments Request

    Science.gov (United States)

    2011-11-29

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC... U.S.C. Chapter 35), agencies are required to publish a Notice in the Federal Register notifying...

  19. 77 FR 4372 - Submission for OMB Review; Comments Request

    Science.gov (United States)

    2012-01-27

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC... U.S.C. Chapter 35), agencies are required to publish a Notice in the Federal Register notifying...

  20. 76 FR 38221 - Submission for OMB Review; Request for Comments

    Science.gov (United States)

    2011-06-29

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; Request for Comments AGENCY: Overseas Private Investment Corporation....S.C. Chapter 35), agencies are required to publish a Notice in the Federal Register notifying...

  1. 76 FR 73741 - Submission for OMB Review; Comments Request

    Science.gov (United States)

    2011-11-29

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC... U.S.C. Chapter 35), agencies are required to publish a Notice in the Federal Register notifying...

  2. 76 FR 74834 - Submission for OMB Review; comments request

    Science.gov (United States)

    2011-12-01

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; comments request AGENCY: Overseas Private Investment Corporation (OPIC... U.S.C. ] Chapter 35), agencies are required to publish a Notice in the Federal Register...

  3. 76 FR 17163 - Submission for OMB Review-Comment Request

    Science.gov (United States)

    2011-03-28

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review--Comment Request AGENCY: Overseas Private Investment Corporation (OPIC.... chapter 35), agencies are required to publish a Notice in the Federal Register notifying the public...

  4. 76 FR 17164 - Submission of OMB Review; Comments Request

    Science.gov (United States)

    2011-03-28

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission of OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC.... Chapter 35), agencies are required to publish a Notice in the Federal Register notifying the public...

  5. 76 FR 17163 - Submission of OMB Review; Comments Request

    Science.gov (United States)

    2011-03-28

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission of OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC.... Chapter 35), agencies are required to publish a Notice in the Federal Register notifying the public...

  6. 77 FR 4374 - Submission for OMB Review; Comments Request

    Science.gov (United States)

    2012-01-27

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC... U.S.C. Chapter 35), agencies are required to publish a Notice in the Federal Register notifying...

  7. 76 FR 17162 - Submission of OMB Review; Comments Request

    Science.gov (United States)

    2011-03-28

    ... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission of OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation (OPIC.... Chapter 35), agencies are required to publish a Notice in the Federal Register notifying the public...

  8. 21 CFR 1002.7 - Submission of data and reports.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Submission of data and reports. 1002.7 Section 1002.7 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED..., or model family of the same product category, a “common aspects report” consolidating...

  9. 78 FR 13399 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-02-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF THE TREASURY Submission for OMB Review; Comment Request February 21, 2013. The Department of the Treasury will submit the following information collection request to the Office of Management and Budget (OMB) for review and clearance in accordance with...

  10. Universities UK Submission to the 2010 Spending Review

    Science.gov (United States)

    Universities UK, 2010

    2010-01-01

    This document represents the submission of Universities UK to the 2010 Spending Review. It sets out why the authors believe universities are critical to the UK's future economic growth, what the impact of cuts to the budget for higher education would be, and the activities which universities are currently pursuing to secure national economic…

  11. 76 FR 78236 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-12-16

    ... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... provisions of the Paperwork Reduction Act (44 U.S.C. Chapter 35). Agency: Minority Business Development Agency (MBDA). Title: Focus Groups on Minority-Owned Business Growth, Opportunities and Barriers...

  12. 76 FR 9541 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-02-18

    ... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... business surveys ] represent the primary source of facts about the structure and function of the U.S. economy, providing essential information to government and the business community in making...

  13. 75 FR 38773 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-07-06

    ... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... provisions of the Paperwork Reduction Act (44 U.S.C. chapter 35). Agency: U.S. Census Bureau. Title: Business... business surveys represent the primary source of facts about the structure and function of the U.S....

  14. 78 FR 65963 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-11-04

    ... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... Administration (NOAA). Title: Survey of Fish Processors and Business Disruptions Caused by Hurricane Sandy. OMB... on distribution networks and business practices from fish processors that process groundfish and...

  15. 77 FR 69434 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-11-19

    ... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... defined in 15 CFR part 285, Sec. 285.14. The information provides a service to customers in business and...: Business or other for-profit organizations; not- for-profit institutions; and Federal, State or...

  16. 76 FR 3877 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-01-21

    ... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... emergency provisions of the Paperwork Reduction Act (44 U.S.C. chapter 35). Agency: Minority Business Development Agency (MBDA). Title: Minority Business Center Program: Communication and Outreach. OMB...

  17. 78 FR 70267 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-11-25

    ... Fishery Conservation and Management Act. Affected Public: Business or other for-profit organizations... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... recovery of normal business practices to the commercial and recreational fishing industries. It seeks...

  18. 78 FR 52499 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-08-23

    ... Conservation and Management Act. Affected Public: Business or other for-profit organizations. Frequency: Weekly... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management..., and managers in the management of the fisheries. The data collection parameters are consistent...

  19. 78 FR 76811 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-12-19

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management and Budget (OMB) for clearance the following proposal for collection of information under the provisions of the Paperwork Reduction Act (44...

  20. 77 FR 4541 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-01-30

    ... Submission for OMB Review; Comment Request The Department of Commerce will submit to the Office of Management... reports, 10 minutes, and documentary evidence requests by the NOAA Fisheries, Southwest Region....gov . Dated: January 24, 2012. Gwellnar Banks, Management Analyst, Office of the Chief...

  1. 78 FR 24184 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-04-24

    ... submit a patent application under the PCT and by the USPTO to fulfill its obligation to process, search... Patent and Trademark Office Submission for OMB Review; Comment Request The United States Patent and....C. Chapter 35). Agency: United States Patent and Trademark Office (USPTO). Title: Patent...

  2. 75 FR 8038 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-02-23

    ... submit a patent application under the PCT and by the USPTO to fulfill its obligation to process, search... Patent and Trademark Office Submission for OMB Review; Comment Request The United States Patent and....C. Chapter 35). Agency: United States Patent and Trademark Office (USPTO). Title: Patent...

  3. 78 FR 12744 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-02-25

    ... patent applications and may also search sequence listings after publication. Affected Public: Businesses... United States Patent and Trademark Office Submission for OMB Review; Comment Request The United States Patent and Trademark Office (USPTO) will submit to the Office of Management and Budget (OMB)...

  4. 77 FR 9213 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-02-16

    ... Public Search Facility to provide patent and trademark collections for searching and retrieval of... United States Patent and Trademark Office Submission for OMB Review; Comment Request The United States Patent and Trademark Office (USPTO) will submit to the Office of Management and Budget (OMB)...

  5. 77 FR 4374 - Submission for OMB Review; Comments Request

    Science.gov (United States)

    2012-01-27

    ... Investment Policy Questionnaire. Form Number: OPIC248. Frequency of Use: Once per investor per project. Type... From the Federal Register Online via the Government Publishing Office OVERSEAS PRIVATE INVESTMENT CORPORATION Submission for OMB Review; Comments Request AGENCY: Overseas Private Investment Corporation...

  6. 40 CFR 89.911 - Submission of exemption requests.

    Science.gov (United States)

    2010-07-01

    ... Enforcement Auditing Section, Engine Programs and Compliance Division (6405-J), Environmental Protection... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Submission of exemption requests. 89.911 Section 89.911 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...

  7. 76 FR 64079 - Notice of Submission for OMB Review

    Science.gov (United States)

    2011-10-17

    ..., including the validity of the methodology and assumptions used; (3) Enhance the quality, utility, and... and research purposes. Copies of the information collection submission for OMB review may be accessed... Internet address ICDocketMgr@ed.gov or faxed to 202-401-0920. Please specify the complete title of...

  8. 75 FR 49454 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-08-13

    ...; ] DEPARTMENT OF AGRICULTURE Submission for OMB Review; Comment Request August 9, 2010. The Department of Agriculture has submitted the following information collection requirement(s) to OMB for review and clearance... of poultry meat and products and live poultry from Argentina and the Mexican States of...

  9. 76 FR 1400 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-01-10

    ...; ] DEPARTMENT OF AGRICULTURE Submission for OMB Review; Comment Request January 5, 2011. The Department of Agriculture has submitted the following information collection requirement(s) to OMB for review and clearance... establish an effective defense against the entry and spread of CSF from Mexican and Chilean swine, pork,...

  10. 76 FR 2328 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-01-13

    ...; ] DEPARTMENT OF AGRICULTURE Submission for OMB Review; Comment Request January 7, 2011. The Department of Agriculture has submitted the following information collection requirement(s) to OMB for review and clearance... (e.g., commingling cattle from multiple operations, exposing young cattle to Mexican cattle); and...

  11. 77 FR 22763 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-04-17

    ... PROTECTION Submission for OMB Review; Comment Request AGENCY: Bureau of Consumer Financial Protection. ACTION... Financial Education Program that has been submitted to the Office of Management and Budget for review and... implementing a strategy to improve the financial literacy of consumers that includes measurable goals...

  12. 29 CFR 515.4 - Submission of plan.

    Science.gov (United States)

    2010-07-01

    ... State child-labor, maximum-hour and minimum-wage laws and regulations; (2) of the location of offices of... 29 Labor 3 2010-07-01 2010-07-01 false Submission of plan. 515.4 Section 515.4 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS UTILIZATION OF...

  13. 7 CFR 1726.35 - Submission of documents to RUS.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Submission of documents to RUS. 1726.35 Section 1726... of documents to RUS. (a) Where to send documents. Documents required to be submitted to RUS under this part are to be sent to the office of the borrower's respective RUS Regional Director, the...

  14. 75 FR 8683 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-02-25

    ... Group Projects Abroad (GPA) program in enhancing the foreign language capacity of the United States. Three surveys will be conducted: a survey of the GPA Project Directors; A survey of 2002-2008 GPA alumni... determining the impact of the GPA program. Requests for copies of the information collection submission...

  15. 21 CFR 314.53 - Submission of patent information.

    Science.gov (United States)

    2010-04-01

    ... Cosmetic Act. This time-sensitive patent information is submitted pursuant to 21 CFR 314.53. I attest that I am familiar with 21 CFR 314.53 and this submission complies with the requirements of the... information is submitted pursuant to 21 CFR 314.53. I attest that I am familiar with 21 CFR 314.53 and...

  16. 20 CFR 725.410 - Submission of additional evidence.

    Science.gov (United States)

    2010-04-01

    ... Submission of additional evidence. (a) After the district director completes the development of medical... the claim was filed by, or on behalf of, a miner, the schedule shall contain a summary of the complete... employer other than the employer who last employed the claimant as a miner, the district director...

  17. Clear Cell Papillary Renal Cell Carcinoma: A Potential Mimic of Conventional Clear Cell Renal Carcinoma on Core Biopsy

    OpenAIRE

    Heath Liddell; Anton Mare; Sean Heywood; Genevieve Bennett; Hin Fan Chan

    2015-01-01

    Clear cell papillary renal cell carcinoma (CCP-RCC) is a recently described, relatively uncommon variant of renal cell carcinoma (RCC) with a reported incidence of 4.1%. Thought to only arise in those with end stage renal disease, CCP-RCC is increasingly identified in those without renal impairment. CCP-RCCs have unique morphologic, genetic, and immunohistochemical features distinguishing them from both conventional clear cell renal cell carcinomas and papillary renal cell carcinomas. Immunoh...

  18. Anterior Crossbite and Crowding Correction with a Series of Clear Aligners Involving Lower Incisor Extraction: "The Clear Way" Case Report.

    Science.gov (United States)

    Bawaskar, Naval Suresh

    2015-01-01

    The Clear Aligner can be used to correct tooth movement without involving extraction, surgery, and other adjunct orthopaedic appliances. Some forms ofattachments are required with clear aligners to achieve all major types of orthodontic tooth movements. The Clear Aligner is a procedure that can be performed by a clinician with computer simulation/calculation. Since the Clear Aligner can be fabricated in steps, it is readily available to change the treatment sequence throughout the course of the treatment in cases of complex malocclusions. The patient can receive any necessary dental procedures with ease during the course of the treatment. The treatment can also be easily resumed even if the patient has not worn the aligners for a period of time. The purpose of this article is to report dental anterior crossbite correction with a series of Clear Aligners without the use of any forms of attachments. The Clear Aligner could be used as an alternative in appropriate cases for those who are reluctant with conventional appliances. PMID:27029089

  19. Relationship of submissive behavior and cyberbullying/cybervictimization: The mediation role of gender

    Directory of Open Access Journals (Sweden)

    Adem Peker

    2012-01-01

    Full Text Available The purpose of this study is to investigate the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. The sample included 193 female and 137 male. Data were obtained using Submissive Behavior Scale and Revized Cyberbullying Inventory and analyzed by SPSS 11.5. Hierarchical regression was used to explore the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. According to results, submissive behavior was positively related to cyber bullying and cyber victimization. In addition gender was found to fully mediate the relationship between submissive behavior and cyber bullying. However, gender failed to mediate the effects of submissive behavior on cyber victimization.

  20. Relationship of submissive behavior and cyberbullying/cybervictimization: The mediation role of gender

    Directory of Open Access Journals (Sweden)

    Adem Peker

    2012-01-01

    Full Text Available The purpose of this study is to investigate the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. The sample included 193 female and 137 male. Data were obtained using Submissive Behavior Scale and Revized Cyberbullying Inventory and analyzed by SPSS 11.5. Hierarchical regression was used to explore the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. According to results, submissive behavior was positively related to cyber bullying and cyber victimization. In addition gender was found to fully mediate the relationship between submissive behavior and cyber bullying. However, gender failed to mediate the effects of submissive behavior on cyber victimization. 

  1. The on – line method for the submission of tax declarations

    OpenAIRE

    Mihai ANTONESCU; Ligia ANTONESCU

    2010-01-01

    Taxpayers can use the method of submission of tax declarations by electronic means of transmission at distance as alternative method of submission of fiscal declarations. For the submission of tax declarations by electronic means of transmission at distance, taxpayers should use the service “Depose on-line declarations” existing on A.N.A.F. portal. This method offers advantages for taxpayers and fiscal agents, in the same time. The taxpayers could use a comfortab...

  2. Relationship of submissive behavior and cyberbullying/cybervictimization: The mediation role of gender

    OpenAIRE

    Adem Peker; Yüksel Eroğlu; Nihan Çitemel

    2012-01-01

    The purpose of this study is to investigate the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. The sample included 193 female and 137 male. Data were obtained using Submissive Behavior Scale and Revized Cyberbullying Inventory and analyzed by SPSS 11.5. Hierarchical regression was used to explore the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. According to result...

  3. Relationship of submissive behavior and cyberbullying/cybervictimization: The mediation role of gender

    OpenAIRE

    Peker, Adem; Eroğlu, Yüksel; Çitemel, Nihan

    2012-01-01

    The purpose of this study is to investigate the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. The sample included 193 female and 137 male. Data were obtained using Submissive Behavior Scale and Revized Cyberbullying Inventory and analyzed by SPSS 11.5. Hierarchical regression was used to explore the mediating role of gender in relationship between submissive behavior and cyber bullying/cyber victimization. According to results, su...

  4. A stochastic framework for clearing of reactive power market

    Energy Technology Data Exchange (ETDEWEB)

    Amjady, N. [Department of Electrical Engineering, Semnan University, Semnan (Iran); Rabiee, A.; Shayanfar, H.A. [Center of excellence for Power System Automation and Operation, Department of Electrical Engineering, Iran University of Science and Technology, Tehran (Iran)

    2010-01-15

    This paper presents a new stochastic framework for clearing of day-ahead reactive power market. The uncertainty of generating units in the form of system contingencies are considered in the reactive power market-clearing procedure by the stochastic model in two steps. The Monte-Carlo Simulation (MCS) is first used to generate random scenarios. Then, in the second step, the stochastic market-clearing procedure is implemented as a series of deterministic optimization problems (scenarios) including non-contingent scenario and different post-contingency states. In each of these deterministic optimization problems, the objective function is total payment function (TPF) of generators which refers to the payment paid to the generators for their reactive power compensation. The effectiveness of the proposed model is examined based on the IEEE 24-bus Reliability Test System (IEEE 24-bus RTS). (author)

  5. Multiobjective clearing of reactive power market in deregulated power systems

    Energy Technology Data Exchange (ETDEWEB)

    Rabiee, A.; Shayanfar, H. [Center of Excellence for Power System Automation and Operation, Electrical Engineering Department, Iran University of Science and Technology (IUST), Narmak, Tehran 16846 (Iran); Amjady, N. [Department of Electrical Engineering, Semnan University, Semnan (Iran)

    2009-09-15

    This paper presents a day-ahead reactive power market which is cleared in the form of multiobjective context. Total payment function (TPF) of generators, representing the payment paid to the generators for their reactive power compensation, is considered as the main objective function of reactive power market. Besides that, voltage security margin, overload index, and also voltage drop index are the other objective functions of the optimal power flow (OPF) problem to clear the reactive power market. A Multiobjective Mathematical Programming (MMP) formulation is implemented to solve the problem of reactive power market clearing using a fuzzy approach to choose the best compromise solution according to the specific preference among various non-dominated (pareto optimal) solutions. The effectiveness of the proposed method is examined based on the IEEE 24-bus reliability test system (IEEE 24-bus RTS). (author)

  6. Clear cell colitis: A form of microscopic colitis in children

    Institute of Scientific and Technical Information of China (English)

    Jan J(o)zefczuk; Bogdan Marian Wozniewicz

    2008-01-01

    AIM: To describe a new clinical and pathological subtype of microscopic colitis in children.METHODS: A selected group of children with abdominal pain, constipation and/or diarrhoea showing discrete or no macroscopic abnormalities on endoscopy was described.RESULTS: Multiple biopsies of colon showed large mononuclear clear cells in lamina propria of mucous membrane provided that good quality histological sections were performed and observed under a higher magnification. Otherwise, they could be misinterpreted as artefacts. Their presence in routine histology might suggest a systemic storage disease (Whipple's disease), and neuronal intestine dysplasia.Using immunohistochemical staining and electron microscopy we confirmed their origin from CD68 positive mononuclear macrophages.CONCLUSION: The presence of large clear cells is a constant microscopic feature. Failure of transient large bowel stationary macrophages plays a role in the pathogenesis of this benign microscopic clear cell colitis,sometimes coexisting with allergy.

  7. Advanced ThioClear process testing. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Lani, B.

    1998-03-01

    Wet scrubbing is the leading proven commercial post-combustion FGD technology available to meet the sulfur dioxide reductions required by the Clean Air Act Amendments. To reduce costs associated with wet FGD, Dravo Lime Company has developed the ThioClear process. ThioClear is an ex-situ forced oxidation magnesium-enhanced lime FGD process. ThioClear process differs from the conventional magnesium-enhanced lime process in that the recycle liquor has minimal suspended solids and the by-products are wallboard quality gypsum and magnesium hydroxide, an excellent reagent for water treatment. The process has demonstrated sulfur dioxide removal efficiencies of +95% in both a vertical spray scrubber tower and a horizontal absorber operating at gas velocities of 16 fps, respectively. This report details the optimization studies and associated economics from testing conducted at Dravo Lime Company`s pilot plant located at the Miami Fort Station of the Cincinnati Gas and Electric Company.

  8. Diagnosis of clear sky ultraviolet radiation for Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Lemus Deschamps, L. [Bureau of Meteorology Research Centre (Australia); Galindo, I.; Solano, R.; Elizalde, A.T.; Fonseca, J. [Centro Universitario de Investigaciones en Ciencias del Ambiente, University of Colima (Mexico)

    2002-07-01

    A discrete-ordinate radiative transfer model is employed to develop a regional clear sky ultraviolet (UV) diagnosis system. The clear sky UV radiation, weighted by the spectral sensitivity of human skin is calculated using the Total Ozone Mapping Spectrometer (TOMS) data sets. Examples of the geographical clear sky UV Index distributions are presented and the model results are compared with surface UV measurements from University of Colima for 1999. [Spanish] Utilizando un modelo de transferencia de radiacion de ordenadas discretas se desarrolla un sistema para el diagnostico de la distribucion de radiacion ultravioleta para cielo despejado en la Republica Mexicana. La radiacion para cielo despejado se obtiene utilizando la respuesta espectral de la piel humana y los datos de satelite de ozono total registrados por el espectrometro TOMS. Se presentan ejemplos del Indice de radiacion ultravioleta (UV Index) calculados con el modelo y se comparan con las mediciones en superficie obtenidas en la Universidad de Colima durante 1999.

  9. Combined Papillated Bowen Disease and Clear Cell Atypical Fibroxanthoma

    Directory of Open Access Journals (Sweden)

    Dimas Suárez-Vilela

    2010-05-01

    Full Text Available We describe a case of papillated Bowen disease (PBD, associated with a clear cell atypical fibroxanthoma (CCAFXA. The epidermal lesion showed a bowenoid papillomatous growth pattern with histologic features suggestive of infection by human papilloma virus (HPV. In the dermis a neoplasm made up by spindled or polygonal cells with wide clear cytoplasm and moderate nuclear pleomorphism was found. Immunohistochemical characteristics of these two lesions were clearly different. The atypical cells of the intraepidermal proliferation were positive for AE1-AE3 anticytokeratin antibody, EMA, p16, p53 and p63. The dermal tumor was positive for vimentin, CD10, CD68, CD99, alpha-1-antitrypsin and c-kit. Histological features and immunohistochemical profile of the dermal tumor corresponded to a CCAFXA, a very uncommon neoplasm of which only 10 cases have been reported. In situ hybridization for numerous types of HPVs was negative in both lesions.

  10. A stochastic framework for clearing of reactive power market

    International Nuclear Information System (INIS)

    This paper presents a new stochastic framework for clearing of day-ahead reactive power market. The uncertainty of generating units in the form of system contingencies are considered in the reactive power market-clearing procedure by the stochastic model in two steps. The Monte-Carlo Simulation (MCS) is first used to generate random scenarios. Then, in the second step, the stochastic market-clearing procedure is implemented as a series of deterministic optimization problems (scenarios) including non-contingent scenario and different post-contingency states. In each of these deterministic optimization problems, the objective function is total payment function (TPF) of generators which refers to the payment paid to the generators for their reactive power compensation. The effectiveness of the proposed model is examined based on the IEEE 24-bus Reliability Test System (IEEE 24-bus RTS). (author)

  11. Multiobjective clearing of reactive power market in deregulated power systems

    International Nuclear Information System (INIS)

    This paper presents a day-ahead reactive power market which is cleared in the form of multiobjective context. Total payment function (TPF) of generators, representing the payment paid to the generators for their reactive power compensation, is considered as the main objective function of reactive power market. Besides that, voltage security margin, overload index, and also voltage drop index are the other objective functions of the optimal power flow (OPF) problem to clear the reactive power market. A Multiobjective Mathematical Programming (MMP) formulation is implemented to solve the problem of reactive power market clearing using a fuzzy approach to choose the best compromise solution according to the specific preference among various non-dominated (pareto optimal) solutions. The effectiveness of the proposed method is examined based on the IEEE 24-bus reliability test system (IEEE 24-bus RTS). (author)

  12. A stochastic framework for clearing of reactive power market

    International Nuclear Information System (INIS)

    This paper presents a new stochastic framework for clearing of day-ahead reactive power market. The uncertainty of generating units in the form of system contingencies are considered in the reactive power market-clearing procedure by the stochastic model in two steps. The Monte-Carlo Simulation (MCS) is first used to generate random scenarios. Then, in the second step, the stochastic market-clearing procedure is implemented as a series of deterministic optimization problems (scenarios) including non-contingent scenario and different post-contingency states. In each of these deterministic optimization problems, the objective function is total payment function (TPF) of generators which refers to the payment paid to the generators for their reactive power compensation. The effectiveness of the proposed model is examined based on the IEEE 24-bus Reliability Test System (IEEE 24-bus RTS).

  13. A new versatile clearing method for brain imaging

    Science.gov (United States)

    Costantini, Irene; Di Giovanna, Antonino Paolo; Allegra Mascaro, Anna Letizia; Silvestri, Ludovico; Müllenbroich, Marie Caroline; Sacconi, Leonardo; Pavone, Francesco S.

    2015-03-01

    Light scattering inside biological tissue is a limitation for large volumes imaging with microscopic resolution. Based on refractive index matching, different approaches have been developed to reduce scattering in fixed tissue. High refractive index organic solvents and water-based optical clearing agents, such as Sca/e, SeeDB and CUBIC have been used for optical clearing of entire mouse brain. Although these methods guarantee high transparency and preservation of the fluorescence, though present other non-negligible limitations. Tissue transformation by CLARITY allows high transparency, whole brain immunolabelling and structural and molecular preservation. This method however requires a highly expensive refractive index matching solution limiting practical applicability to large volumes. In this work we investigate the effectiveness of a water-soluble clearing agent, the 2,2'-thiodiethanol (TDE) to clear mouse and human brain. TDE does not quench the fluorescence signal, is compatible with immunostaining and does not introduce any deformation at sub-cellular level. The not viscous nature of the TDE make it a suitable agent to perform brain slicing during serial two-photon (STP) tomography. In fact, by improving penetration depth it reduces tissue slicing, decreasing the acquisition time and cutting artefacts. TDE can also be used as a refractive index medium for CLARITY. The potential of this method has been explored by imaging blocks of dysplastic human brain transformed with CLARITY, immunostained and cleared with the TDE. This clearing approach significantly expands the application of single and two-photon imaging, providing a new useful method for quantitative morphological analysis of structure in mouse and human brain.

  14. A versatile new technique to clear mouse and human brain

    Science.gov (United States)

    Costantini, Irene; Di Giovanna, Antonino Paolo; Allegra Mascaro, Anna Letizia; Silvestri, Ludovico; Müllenbroich, Marie Caroline; Sacconi, Leonardo; Pavone, Francesco S.

    2015-07-01

    Large volumes imaging with microscopic resolution is limited by light scattering. In the last few years based on refractive index matching, different clearing approaches have been developed. Organic solvents and water-based optical clearing agents have been used for optical clearing of entire mouse brain. Although these methods guarantee high transparency and preservation of the fluorescence, though present other non-negligible limitations. Tissue transformation by CLARITY allows high transparency, whole brain immunolabelling and structural and molecular preservation. This method however requires a highly expensive refractive index matching solution limiting practical applicability. In this work we investigate the effectiveness of a water-soluble clearing agent, the 2,2'-thiodiethanol (TDE) to clear mouse and human brain. TDE does not quench the fluorescence signal, is compatible with immunostaining and does not introduce any deformation at sub-cellular level. The not viscous nature of the TDE make it a suitable agent to perform brain slicing during serial two-photon (STP) tomography. In fact, by improving penetration depth it reduces tissue slicing, decreasing the acquisition time and cutting artefacts. TDE can also be used as a refractive index medium for CLARITY. The potential of this method has been explored by imaging a whole transgenic mouse brain with the light sheet microscope. Moreover we apply this technique also on blocks of dysplastic human brain tissue transformed with CLARITY and labeled with different antibody. This clearing approach significantly expands the application of single and two-photon imaging, providing a new useful method for quantitative morphological analysis of structure in mouse and human brain.

  15. Cladoceran zooplankton abundance under clear and snow-covered ice

    Science.gov (United States)

    DeBates, T.J.; Chipps, S.R.; Ward, M.C.; Werlin, K.B.; Lorenzen, P.B.

    2003-01-01

    We described the distribution of cladoceran zooplankton under the ice in a natural, glacial lake. Local light availability apparently altered the spatial distribution of cladocerans. Light levels measured under snow-covered areas (0.178 lux) were an order of magnitude less than those measured at the same depth under clear ice (1.750 lux). Cladoceran density under snow-covered areas was significantly higher (Bosmina spp.=3.34/L; Daphnia spp.=0.61/L) than cladoceran abundance under clear ice (Bosmina spp.=0.91/L; Daphnia spp.=0.19/L).

  16. Clear cell odontogenic carcinoma of maxilla: A diagnostic challenge

    Directory of Open Access Journals (Sweden)

    Fouzia Siraj

    2016-01-01

    Full Text Available Clear cell odontogenic carcinoma (CCOC is a rare odontogenic tumor which occurs mostly in the mandible. It is primarily seen in fifth to seventh decades with a female predilection. We report a case of CCOC in the maxillary arch of a 66-year-old woman. Morphologic examination along with histochemical and immunohistochemical markers led to the establishment of the diagnosis. It is important to diagnose this entity and differentiate it from other clear cell tumors in the head and neck region as it is a locally aggressive tumor with a propensity for regional, nodal, and distant metastasis.

  17. Effects of Clear-Fell Harvest on Bat Home Range

    OpenAIRE

    Borkin, Kerry M.; Parsons, Stuart

    2014-01-01

    We investigated effects of roost loss due to clear-fell harvest on bat home range. The study took place in plantation forest, inhabited by the New Zealand long-tailed bat (Chalinolobus tuberculatus), in which trees are harvested between the ages 26–32 years. We determined home ranges by radiotracking different bats in areas that had and had not been recently clear-fell harvested. Home ranges were smaller in areas that had been harvested. Adult male bats selected 20–25 year old stands within h...

  18. A RARE CASE OF CLEAR CELL SARCOMA OF TENDONS

    Directory of Open Access Journals (Sweden)

    Ramesh Kumar

    2014-01-01

    Full Text Available Clear cell sarcoma of tendons & aponeuroses , is a rare malignancy derived from neural crest cells. It commonly presents in young adults in extremities. It is usually a high grade tumor with poor survival rates. Grossly , the tumor is circumscribed with a histologic pattern of uniform polygonal to fusiform cells with clear to pale eosinophilic cytoplasm divided into variably sized clusters by fibrous septa. Immunohistochemistry reveals neopalstic cells which are positive for HMB - 45 & react with antibody against S - 100 protein. Mainstay treatment remains wide excision of tumor . The role of chemotherapy & radiotherapy are reported to be limited. We report this case in view of its rarity.

  19. Computer analyses on loop seal clearing experiment at PWR PACTEL

    International Nuclear Information System (INIS)

    Highlights: • Code analyses of loop seal clearing experiment with PWR PACTEL are introduced. • TRACE and APROS system codes are used in the analyses. • Main events of the experiment are well predicted with both codes. • Discrepancies are observed on the secondary side and in the core region. • Loop seal clearing phenomenon is well simulated with both codes. - Abstract: Water seal formation in the loop seal in pressurized water reactors can occur during a small or intermediate break loss-of-coolant accident, causing temporary fuel overheating. Quantification of the accuracy of overheating prediction is of interest in the best-estimate safety analyses, even though the peak cladding temperatures due to the water seal formation in the loop seal seldom approach acceptance criteria as such. The aim of this study was to test and evaluate the accuracy with which the thermal–hydraulic system code nodalizations of the PWR PACTEL predict loop seal clearing in a small break loss-of-coolant-accident test performed with the PWR PACTEL facility. PWR PACTEL is a thermal–hydraulic test facility with two loops and vertical inverted U-tube steam generators. Post-test simulations were performed with the TRACE and APROS system codes. In the post-test simulations, the main events of the transient such as the decrease in the core water level, depressurization of the primary circuit, and the behavior of the water seal formation and clearing in the loop seal were predicted satisfactorily by both codes. However, discrepancies with the experiment results were observed in the analyses with both codes, for example the core temperature excursions were halted too early and the peak temperature predictions were too low. The core water level increase caused by loop seal clearing was overestimated with both codes, and the pressure and temperature were overestimated on the secondary side of the steam generators. Loop Seal 2 was evidently cleared out while Loop Seal 1 remained closed

  20. Glycogen-rich clear cell carcinoma of the breast

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Paulsen, S M

    1987-01-01

    cells were stained by antisera to carcinoembryonic antigen, keratin and epithelial membrane antigen, but not by antisera to alpha-lactalbumin, desmin or vimentin. Ultrastructurally, the epithelial derivation of the tumour was confirmed. Only a few intracytoplasmic lumina were demonstrated. The tumour......The light microscopic, immunohistochemical and ultrastructural features of a clear cell carcinoma of the breast have been studied. Both intraductal and invasive components were found. Histochemistry showed large amounts of intracytoplasmic glycogen and sparse neutral mucin in the tumour. The tumour...... was classified as a mucin-containing variant of glycogen-rich, clear cell carcinoma of the breast....

  1. 75 FR 44969 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Science.gov (United States)

    2010-07-30

    ...: Submission for OMB Review; Comment Request AGENCY: Centers for Medicare & Medicaid Services. In compliance... that have access barriers to information including language, literacy, location, and culture...

  2. 78 FR 52776 - Documents to Support Submission of an Electronic Common Technical Document; Availability

    Science.gov (United States)

    2013-08-26

    ... self-addressed adhesive label to assist that office in processing your requests. See the SUPPLEMENTARY... submission processing and review, refine the characterization of promotional marketing and...

  3. Does gently clearing the nasal passage affect odor identification?

    Directory of Open Access Journals (Sweden)

    Mitchell G. Spring

    2014-12-01

    Full Text Available Identifying scents in a wine’s bouquet is considered one of the most important steps in the process of wine tasting. An individual’s ability to successfully do this is dependent on the sense of smell; thus, altering the nasal microenvironment could have a powerful effect on the wine tasting experience. In the present study, we examined olfactory performance in healthy participants who cleared their nasal cavity before odorant presentations. Fifty undergraduate participants were assessed with a standardized test of olfaction requiring the recognition of a battery of odors. Half of these participants cleared mucus from their nasal cavities (by gently blowing their noses prior to the assessment. No difference was found in performance between those who cleared their nasal passages and those who did not. Further, data were not different than known population data from the test. These data suggest that gently clearing the nasal cavity before presentation of odorants bears no effect on the ability to perceive those odor qualities.

  4. Clear cell adenocarcinoma of the bladder with intravesical cervical invasion.

    Science.gov (United States)

    Marchalik, Daniel; Krishnan, Jayashree; Verghese, Mohan; Venkatesan, Krishnan

    2015-01-01

    A 26-year-old woman with a complicated urological and gynecological history with uterine didelphys with bilaterally inserting intravesical cervical oses presented with cyclical haematuria. Work up revealed a mass in the ectopic cervical os and adjacent bladder wall. Subsequent resection confirmed a clear cell adenocarcinoma of urological origin with invasion into neighbouring os. PMID:26109625

  5. 78 FR 72475 - Derivatives Clearing Organizations and International Standards

    Science.gov (United States)

    2013-12-02

    ... Clearing Organization General Provisions and Core Principles, 76 FR 69334 (Nov. 8, 2011). These regulations... Market Utilities as Systemically Important, 76 FR 44763, 44774 (July 27, 2011) (final rule). In... deems appropriate. \\11\\ 76 FR 44766. \\12\\ See Press Release, Financial Stability Oversight...

  6. 76 FR 14471 - Clearing Agency Standards for Operation and Governance

    Science.gov (United States)

    2011-03-16

    ... CFTC have proposed rules to define these terms. See Exchange Act No. 63452 (December 7, 2010), 75 FR...-the- counter market. See Exchange Act Release No. 63825 (February 2, 2011), 76 FR 10948 (February 28... five entities to clear credit default swaps. See Exchange Act Release Nos. 60372 (July 23, 2009), 74...

  7. Clear Cell Chondrosarcoma in Association With Niemann-Pick Disease

    Directory of Open Access Journals (Sweden)

    K. N. Srikanth

    2005-01-01

    Full Text Available Purpose: The purpose of this case report is to bring to light this unusual combination of two rare diseases, namely Neimann-Pick disease Type B and clear cell chondrosarcoma occurring in the same patient. This has not previously been reported in the world literature.

  8. 76 FR 3697 - Risk Management Requirements for Derivatives Clearing Organizations

    Science.gov (United States)

    2011-01-20

    ....\\29\\ \\29\\ See 75 FR at 63750. In that proposed rulemaking, the provisions relating to the Risk... Trading Commission 17 CFR Part 39 Risk Management Requirements for Derivatives Clearing Organizations...; ] COMMODITY FUTURES TRADING COMMISSION 17 CFR Part 39 RIN 3038-AC98 Risk Management Requirements...

  9. Multifocal Rhizopus microsporus lung infection following brush clearing

    Directory of Open Access Journals (Sweden)

    Artsiom V. Tsyrkunou

    2014-10-01

    Full Text Available We report a case of pulmonary Rhizopus microsporus infection in a patient with untreated diabetes following brush clearing. The patient was successfully treated with a combined medical and surgical approach with complete resolution of the lung lesions and remains asymptomatic at 11-month follow-up.

  10. Bifunctional mesoporous silicas with clearly distinguished localization of grafted groups

    Science.gov (United States)

    Roik, N. V.; Belyakova, L. A.

    2013-12-01

    Bifunctional mesoporous silicas with clearly distinguished localization of grafted groups on the surface of particles and inside their pores were obtained by means of sol-gel synthesis with postsynthetic vapor-phase treatment in vacuum. It was found that the synthesized materials have the hexagonally ordered porous structure typical of MCM-41 type silica.

  11. Marketing Strategies of United Kingdom Universities during Clearing and Adjustment

    Science.gov (United States)

    Mogaji, Emmanuel

    2016-01-01

    Purpose: The clearing system in the UK enables students without a university place after exam results have been announced to find suitable vacancies, as it is important for universities to fill their vacancies as any shortfall loses them a lot of money. The purpose of this paper is to examine marketing strategies adopted by UK universities on…

  12. Antimalarial Drugs Clear Resistant Parasites from Partially Immune Hosts

    OpenAIRE

    Cravo, Pedro; Culleton, Richard; Hunt, Paul; Walliker, David; Mackinnon, Margaret J.

    2001-01-01

    Circumstantial evidence in human malaria suggests that elimination of parasites by drug treatment meets higher success rates in individuals having some background immunity. In this study, using the rodent malaria model Plasmodium chabaudi, we show that drug-resistant parasites can be cleared by drugs when the host is partially immune.

  13. Seeing Clearly (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2014-05-08

    If you’re not seeing the world as clearly as you used to, you might be among the millions of people suffering from vision impairment. In this podcast, Dr. John Crews discusses ways to take care of your eyes.  Created: 5/8/2014 by MMWR.   Date Released: 5/8/2014.

  14. 18 CFR 367.1840 - Account 184, Clearing accounts.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Account 184, Clearing accounts. 367.1840 Section 367.1840 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... POWER ACT AND NATURAL GAS ACT UNIFORM SYSTEM OF ACCOUNTS FOR CENTRALIZED SERVICE COMPANIES SUBJECT...

  15. Treatment results and prognostic factors of clear cell ovarian carcinomas and ovarian carcinomas with clear cell component

    Directory of Open Access Journals (Sweden)

    M. D. Ahmedova

    2014-07-01

    Full Text Available The most important prognostic factors for clear cell carcinoma (CCC are clinical and morphological signs and clinical stage of the disease. Analyses of 5-year survival in patients with I stage of CCC is 69 %, in II stage – 55 %, in III stage – 14 % and in IV stage – 4 % patients. We analyzed distant results of treatment of 71 patients with CCC and of 25 patients with mixed malignant ovaries neoplasm with obligatory clear cell component taking into consideration main clinical and morphological sings of disease. On the base of performed reseal we revealed that morphological structure of the tumors and stage of the disease exerted heist influence on the exponent of survival of the patients with clear CCC ovaries neoplasm. Besides, there is a correlation between exponent of patients’ survival and radicalized of surgery, character of tumor growth, differentiation degree, cell anaplasia and mitotic activity of tumor cells.

  16. The potential of clear-sky carbon dioxide satellite retrievals

    Science.gov (United States)

    Nelson, Robert R.; O'Dell, Christopher W.; Taylor, Thomas E.; Mandrake, Lukas; Smyth, Mike

    2016-04-01

    Since the launch of the Greenhouse Gases Observing Satellite (GOSAT) in 2009, retrieval algorithms designed to infer the column-averaged dry-air mole fraction of carbon dioxide (XCO2) from hyperspectral near-infrared observations of reflected sunlight have been greatly improved. They now generally include the scattering effects of clouds and aerosols, as early work found that absorption-only retrievals, which neglected these effects, often incurred unacceptably large errors, even for scenes with optically thin cloud or aerosol layers. However, these "full-physics" retrievals tend to be computationally expensive and may incur biases from trying to deduce the properties of clouds and aerosols when there are none present. Additionally, algorithms are now available that can quickly and effectively identify and remove most scenes in which cloud or aerosol scattering plays a significant role. In this work, we test the hypothesis that non-scattering, or "clear-sky", retrievals may perform as well as full-physics retrievals for sufficiently clear scenes. Clear-sky retrievals could potentially avoid errors and biases brought about by trying to infer properties of clouds and aerosols when none are present. Clear-sky retrievals are also desirable because they are orders of magnitude faster than full-physics retrievals. Here we use a simplified version of the Atmospheric Carbon Observations from Space (ACOS) XCO2 retrieval algorithm that does not include the scattering and absorption effects of clouds or aerosols. It was found that for simulated Orbiting Carbon Observatory-2 (OCO-2) measurements, the clear-sky retrieval had errors comparable to those of the full-physics retrieval. For real GOSAT data, the clear-sky retrieval had errors 0-20 % larger than the full-physics retrieval over land and errors roughly 20-35 % larger over ocean, depending on filtration level. In general, the clear-sky retrieval had XCO2 root-mean-square errors (RMSEs) of less than 2.0 ppm, relative to

  17. Clear-air radar observations of the atmospheric boundary layer

    Science.gov (United States)

    Ince, Turker

    2001-10-01

    This dissertation presents the design and operation of a high-resolution frequency-modulated continuous-wave (FM- CW) radar system to study the structure and dynamics of clear-air turbulence in the atmospheric boundary layer (ABL). This sensitive radar can image the vertical structure of the ABL with both high spatial and temporal resolutions, and provide both qualitative information about the morphology of clear-air structures and quantitative information on the intensity of fluctuations in refractive-index of air. The principles of operation and the hardware and data acquisition characteristics of the radar are described in the dissertation. In October 1999, the radar participated in the Cooperative Atmosphere-Surface Exchange Study (CASES'99) Experiment to characterize the temporal structure and evolution of the boundary-layer features in both convective and stable conditions. The observed structures include clear-air convection, boundary layer evolution, gravity waves, Kelvin-Helmholtz instabilities, stably stratified layers, and clear-air turbulence. Many of the S-band radar images also show high- reflectivity returns from Rayleigh scatterers such as insects. An adaptive median filtering technique based on local statistics has, therefore, been developed to discriminate between Bragg and Rayleigh scattering in clear-air radar observations. The filter is tested on radar observations of clear air convection with comparison to two commonly used image processing techniques. The dissertation also examines the statistical mean of the radar-measured C2n for clear-air convection, and compares it with the theoretical predictions. The study also shows that the inversion height, local thickness of the inversion layer, and the height of the elevated atmospheric layers can be estimated from the radar reflectivity measurements. In addition, comparisons to the radiosonde-based height estimates are made. To examine the temporal and spatial structure of C2n , the dissertation

  18. The potential of clear-sky carbon dioxide satellite retrievals

    Directory of Open Access Journals (Sweden)

    R. R. Nelson

    2015-12-01

    Full Text Available Since the launch of the Greenhouse Gases Observing Satellite (GOSAT in 2009, retrieval algorithms designed to infer the column-averaged dry-air mole fraction of carbon dioxide (XCO2 from hyperspectral near-infrared observations of reflected sunlight have been greatly improved. They now generally include the scattering effects of clouds and aerosols, as early work found that absorption-only retrievals, which neglected these effects, often incurred unacceptably large errors, even for scenes with optically thin cloud or aerosol layers. However, these "full-physics" retrievals tend to be computationally expensive and may incur biases from trying to deduce the properties of clouds and aerosols when there are none present. Additionally, algorithms are now available that can quickly and effectively identify and remove most scenes in which cloud or aerosol scattering plays a significant role. In this work, we test the hypothesis that non-scattering, or "clear-sky", retrievals may perform as well as full-physics retrievals for sufficiently clear scenes. Clear-sky retrievals could potentially avoid errors and biases brought about by trying to infer properties of clouds and aerosols when none are present. Clear-sky retrievals are also desirable because they are orders of magnitude faster than full-physics retrievals. Here we use a simplified version of the Atmospheric Carbon Observations from Space (ACOS XCO2 retrieval algorithm that does not include the scattering and absorption effects of clouds or aerosols. It was found that for simulated Orbiting Carbon Observatory-2 (OCO-2 measurements, the clear-sky retrieval had errors comparable to those of the full-physics retrieval. For real GOSAT data, the clear-sky retrieval had nearly indistinguishable error characteristics over land, but roughly 30–60 % larger errors over ocean, depending on filtration level, compared to the full-physics retrieval. In general, the clear-sky retrieval had XCO2 root

  19. Validation of the McClear clear-sky model in desert conditions with three stations in Israel

    Science.gov (United States)

    Lefèvre, Mireille; Wald, Lucien

    2016-03-01

    The new McClear clear-sky model, a fast model based on a radiative transfer solver, exploits the atmospheric properties provided by the EU-funded Copernicus Atmosphere Monitoring Service (CAMS) to estimate the solar direct and global irradiances received at ground level in cloud-free conditions at any place any time. The work presented here focuses on desert conditions and compares the McClear irradiances to coincident 1 min measurements made in clear-sky conditions at three stations in Israel which are distant from less than 100 km. The bias for global irradiance is comprised between 2 and 32 W m-2, i.e. between 0 and 4 % of the mean observed irradiance (approximately 830 W m-2). The RMSE ranges from 30 to 41 W m-2 (4 %) and the squared correlation coefficient is greater than 0.976. The bias for the direct irradiance at normal incidence (DNI) is comprised between -68 and +13 W m-2, i.e. between -8 and 2 % of the mean observed DNI (approximately 840 W m-2). The RMSE ranges from 53 (7 %) to 83 W m-2 (10 %). The squared correlation coefficient is close to 0.6. The performances are similar for the three sites for the global irradiance and for the DNI to a lesser extent, demonstrating the robustness of the McClear model combined with CAMS products. These results are discussed in the light of those obtained by McClear for other desert areas in Egypt and United Arab Emirates.

  20. AIDS and journalism. Trying to tell too clear a story.

    Science.gov (United States)

    Cohen, J

    1994-12-01

    Much in science is complex. Scientists, by definition, work within the realm of complex hypothesis, empirical evidence, and proof. Questions, answers, details, complexities; that is the domain of the scientist. Journalists, on the other hand, are paid to develop and present stories which are clearly read and interpreted by the general public. The mechanics and dynamics of HIV and AIDS are among the most complex scientific challenges in the history of humankind. Journalists calling upon scientists to obtain and report clear, concise, information about the agent and its resulting pandemic are therefore surely not always going to receive simple, readily reportable responses. HIV is a moving target upon which research continues. While there are some definitively affirmative and some definitively negative factors about HIV, the gray areas and speculation remain vast. The author gives a few examples of AIDS stories which the media mishandled because they were trying to tell too clear a story. He then discusses stories flawed because scientists managed to present clear information about which journalists were overly skeptical. In one case, the public was informed that AIDS vaccines were not working, with headlines which insinuated that the vaccines themselves were causing infections. None of the vaccines, however, contained infectious materials. As a result, people became overly fearful of participating in HIV vaccine trials. Coverage of the potential identification of HIV-3 was premature and only scared people, while Rolling Stone magazine's article hypothesizing the origin of HIV via trials of a contaminated polio vaccine in the Belgium Congo in the late 1950s should not have been published. Clear answers about HIV/AIDS are few and far between, but interesting and significant stories can still be found; they are just hard to tell. PMID:12319130

  1. Clear cell ovarian cancer and endometriosis: is there a relationship?

    Science.gov (United States)

    Suzin, Jacek; Obirek, Katarzyna; Sochacka, Amanda; Łoszakiewicz, Marta

    2016-01-01

    Introduction Ovarian clear cell carcinoma is a rare type of ovarian cancer. In recent years, issues of the common genetic origin of endometriosis and ovarian clear cell carcinoma have been raised. Aim of this study Aim of this study was to evaluate the prevalence of this type of cancer, risk factors, prognosis and its potential aetiological association with endometriosis. Material and methods In a retrospective study, we analysed histopathological data of patients operated in the First Department of Gynaecology and Obstetrics (MU, Lodz) due to ovarian cancer in 2004-2014. Among the 394 patients operated on for ovarian cancer, clear cell carcinoma was found in 0.02% (9/394). Menstrual history, parity, comorbidities, data from physical examination, operational protocols and histopathological diagnoses were analysed. Follow-up was obtained from 77.8% of patients. Statistical analysis was performed using Microsoft Excel 2013. Results The mean age of patients at diagnosis was 57.6 years; the BMI in the study group was 27.2; the majority of patients were multiparous (77.8%). Clear cell carcinoma was detected mostly at stage Ia (n = 4). The concentration of Ca125 in the study group had an average of 142.75 U/ml and a median of 69.3 U/ml. The coexistence of endometriosis could not be clinically or histologically confirmed amongst our patients. The most common comorbidity in the study group was hypertension. Conclusions In our clinical material, ovarian clear cell carcinoma is a rare histopathological specimen with a prognostic value comparable to that of serous ovarian cancer. Due to the rarity of this histopathological subtype, proving a cause-and-effect relationship between it and endometriosis can only be elucidated through statistical studies of the entire population.

  2. Deaf children's use of clear visual cues in mindreading.

    Science.gov (United States)

    Hao, Jian; Su, Yanjie

    2014-11-01

    Previous studies show that typically developing 4-year old children can understand other people's false beliefs but that deaf children of hearing families have difficulty in understanding false beliefs until the age of approximately 13. Because false beliefs are implicit mental states that are not expressed through clear visual cues in standard false belief tasks, the present study examines the hypothesis that the deaf children's developmental delay in understanding false beliefs may reflect their difficulty in understanding a spectrum of mental states that are not expressed through clear visual cues. Nine- to 13-year-old deaf children of hearing families and 4-6-year-old typically developing children completed false belief tasks and emotion recognition tasks under different cue conditions. The results indicated that after controlling for the effect of the children's language abilities, the deaf children inferred other people's false beliefs as accurately as the typically developing children when other people's false beliefs were clearly expressed through their eye-gaze direction. However, the deaf children performed worse than the typically developing children when asked to infer false beliefs with ambiguous or no eye-gaze cues. Moreover, the deaf children were capable of recognizing other people's emotions that were clearly conveyed by their facial or body expressions. The results suggest that although theory-based or simulation-based mental state understanding is typical of hearing children's theory of mind mechanism, for deaf children of hearing families, clear cue-based mental state understanding may be their specific theory of mind mechanism. PMID:25104224

  3. 78 FR 54507 - Clearing Agency; the Options Clearing Corporation; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2013-09-04

    ..., including number of outstanding shares, number of outstanding shareholders and overall trading volume. The... collateral for a particular clearing member, shares of an otherwise eligible security held as margin. II... market price ofconcentrated security positions by identifying the two individual securities whose...

  4. 76 FR 27697 - Self-Regulatory Organizations; Options Clearing Corporation; Notice of Filing of Proposed Rule...

    Science.gov (United States)

    2011-05-12

    ...' Fedwire Funds Service on a settlement day, if necessary, during an emergency situation.\\4\\ Such an... Commission, 100 F Street, NE., Washington, DC 20549-1090. All submissions should refer to File Number SR-OCC... printing in the Commission's Public Reference Section, 100 F Street, NE., Washington, DC 20549, on...

  5. Clear sky atmosphere at cm-wavelengths from climatology data

    CERN Document Server

    Lew, Bartosz

    2015-01-01

    We utilise ground-based, balloon-born and satellite climatology data to reconstruct site and season-dependent vertical profiles of precipitable water vapour (PWV). We use these profiles to numerically solve radiative transfer through the atmosphere, and derive atmospheric brightness temperature ($T_{\\rm atm}$) and optical depth ($\\tau$) at the centimetre wavelengths. We validate the reconstruction by comparing the model column PWV, with photometric measurements of PWV, performed in the clear sky conditions towards the Sun. Based on the measurements, we devise a selection criteria to filter the climatology data to match the PWV levels to the expectations of the clear sky conditions. We apply the reconstruction to the location of the Polish 32-metre radio telescope, and characterise $T_{\\rm atm}$ and $\\tau$ year-round, at selected frequencies. We also derive the zenith distance dependence for these parameters, and discuss shortcomings of using planar, single-layer, and optically thin atmospheric model approxima...

  6. Status of crystal clear collaboration activities on scintillators

    CERN Document Server

    Auffray, Etiennette

    2000-01-01

    Since about 10 years, the Crystal Clear Collaboration at CERN works on systematic investigations of new scintillating crystals and their application in science and industry. A large amount of new type scintillators had been characterised and optimised in terms of emission spectra, light yield, production yield and radiation hardness. As a result, one of those crystals, PbWO4, was chosen to be the baseline solution for the CMS electromagnetic calorimeter at CERN and is actually produced in industrial scale with a quantity of about 1000 crystals per month. Another baseline of actual research interests in Crystal Clear is the construction of a PET-scanning prototype made of small, high light yield crystals for future medical applications. As a result of the different research activities on scintillating crystals, a website is currently under construction, which provides access to a large crystal database. Beside general and methodological informations on scintillating crystals, the database will contain a large ...

  7. Aberrant expression of metallothioneins in clear cell renal cell carcinomas

    Directory of Open Access Journals (Sweden)

    Rymar V. I.

    2015-12-01

    Full Text Available Aim. To find candidate tumor suppressor genes among metallothioneins for clear cell renal cell carcinoma. Methods. Analysis of the microarray data, quantitative PCR. Results. We found three genes encoding metallothioneines that showed reduced expression in different types of renal tumors, using protocol of the cross-platform meta-analysis of microarray data with normalization on several reference genes. Decreased expression of the MT1G, MT1F, and MT1H genes in clear cell renal cell carcinoma was confirmed by qPCR. Conclusions. The MT1G, MT1F and MT1H genes as well as may be considered as the candidate tumor suppressor genes for ccRCC.

  8. Enhanced OCT imaging of embryonic tissue with optical clearing

    International Nuclear Information System (INIS)

    Optical coherence tomography (OCT) holds great promise as a routine research tool for 3-D analysis of mammalian embryos. However, despite the depth penetration afforded by this imaging modality, light attenuation in tissues imposes limitations. Here we studied the optical clearing effect of different concentrations of glycerol in mouse embryos. Depth- and time-resolved profiles for OCT signal enhancement are presented. We found that application of 50% glycerol resulted in 51.5±12.5% improvement of the OCT signal, while 25% glycerol enhanced the OCT signal by 25.2±7.3% at the depth of about 200 to 500 μm, and the glycerol permeability rate was estimated as 26.7±6 μm/min. These results demonstrate that embryonic imaging is improved by application of glycerol as optical clearing agent

  9. ClearFuels-Rentech Integrated Biorefinery Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Pearson, Joshua [Project Director

    2014-02-26

    The project Final Report describes the validation of the performance of the integration of two technologies that were proven individually on a pilot scale and were demonstrated as a pilot scale integrated biorefinery. The integrated technologies were a larger scale ClearFuels’ (CF) advanced flexible biomass to syngas thermochemical high efficiency hydrothermal reformer (HEHTR) technology with Rentech’s (RTK) existing synthetic gas to liquids (GTL) technology.

  10. Agroforestry is promising for previously cleared hardwood rangelands

    OpenAIRE

    McCreary, Doug

    2001-01-01

    Livestock grazing is the primary economic use of most hardwood rangelands in the coastal foothills of California. But owners of these lands may be able to increase revenues by simultaneously producing two crops, trees and sheep. In 1993, we initiated an agroforestry project at the UC Hopland Research and Extension Center to study the ability of three pine species and one hybrid to grow on cleared hardwood rangelands that are grazed by sheep. This study also evaluated the response of planted s...

  11. Clear-cut monitoring on French region of Limousin

    OpenAIRE

    Salvado, A; Stach, N.; Deshayes, M.; Lascaux, P.

    2007-01-01

    Since 2006, IFN (French National Forest Inventory) has been conducting an annual survey of clear-cuts on the French administrative region of Limousin (17060 km2). This work has been initiated as a part of the GSE (Global monitoring for environment and security Service Element) Forest monitoring European project, a common initiative of the European Commission and ESA. The goal of this project is to bridge the gap between producers of information derived from satellite data and users of this...

  12. Image reconstruction for the ClearPETTM Neuro

    International Nuclear Information System (INIS)

    ClearPETTM is a family of small-animal PET scanners which are currently under development within the Crystal Clear Collaboration (CERN). All scanners are based on the same detector block design using individual LSO and LuYAP crystals in phoswich configuration, coupled to multi-anode photomultiplier tubes. One of the scanners, the ClearPETTM Neuro is designed for applications in neuroscience. Four detector blocks with 64 2x2x10 mm LSO and LuYAP crystals, arranged in line, build a module. Twenty modules are arranged in a ring with a ring diameter of 13.8 cm and an axial size of 11.2 cm. An insensitive region at the border of the detector heads results in gaps between the detectors axially and tangentially. The detectors are rotating by 360o in step and shoot mode during data acquisition. Every second module is shifted axially to compensate partly for the gaps between the detector blocks in a module. This unconventional scanner geometry requires dedicated image reconstruction procedures. Data acquisition acquires single events that are stored with a time mark in a dedicated list mode format. Coincidences are associated off line by software. After sorting the data into 3D sinograms, image reconstruction is performed using the Ordered Subset Maximum A Posteriori One-Step Late (OSMAPOSL) iterative algorithm implemented in the Software for Tomographic Image Reconstruction (STIR) library. Due to the non-conventional scanner design, careful estimation of the sensitivity matrix is needed to obtain artifact-free images from the ClearPETTM Neuro

  13. Durational cues to word boundaries in clear speech

    OpenAIRE

    Cutler, A.; Butterfield, S.

    1990-01-01

    One of a listener’s major tasks in understanding continuous speech in segmenting the speech signal into separate words. When listening conditions are difficult, speakers can help listeners by deliberately clear speech. We found that speakers do indeed attempt to makr word boundaries; moreover, they differentiate between word boundaries in a way which suggest they are sensitive to listener needs. Application of heuristic segmentation strategies makes word boundaries before strong syllables eas...

  14. Clear sky atmosphere at cm-wavelengths from climatology data

    OpenAIRE

    Lew, Bartosz; Uscka-Kowalkowska, Joanna

    2015-01-01

    We utilise ground-based, balloon-borne and satellite climatology data to reconstruct site and season-dependent vertical profiles of precipitable water vapour (PWV). We use these profiles to solve radiative transfer through the atmosphere, and derive atmospheric brightness temperature ($T_{\\rm atm}$) and optical depth ($\\tau$) at centimetre wavelengths. We validate the reconstruction by comparing the model column PWV with photometric measurements of PWV, performed in clear sky conditions point...

  15. Clear Cell Chondrosarcoma in Association With Niemann-Pick Disease

    OpenAIRE

    Sumathi, V. P.; Grimer, R. J.; Davies, A. M.; Kulkarni, A.; Srikanth, K. N.

    2005-01-01

    Purpose: The purpose of this case report is to bring to light this unusual combination of two rare diseases, namely Neimann-Pick disease Type B and clear cell chondrosarcoma occurring in the same patient. This has not previously been reported in the world literature. Subject: Niemann-Pick disease (NPD) is a rare autosomal recessive inborn error of metabolism. Type B NPD is even rarer. It is a lysosomal storage disorder affecting children and adolescents often causing death in early childhood,...

  16. Experimental characterization of the Clear-PEM scanner spectrometric performance

    Science.gov (United States)

    Bugalho, R.; Carriço, B.; Ferreira, C. S.; Frade, M.; Ferreira, M.; Moura, R.; Ortigão, C.; Pinheiro, J. F.; Rodrigues, P.; Rolo, I.; Silva, J. C.; Trindade, A.; Varela, J.

    2009-10-01

    In the framework of the Clear-PEM project for the construction of a high-resolution and high-specificity scanner for breast cancer imaging, a Positron Emission Mammography tomograph has been developed and installed at the Instituto Português de Oncologia do Porto hospital. The Clear-PEM scanner is mainly composed by two planar detector heads attached to a robotic arm, trigger/data acquisition electronics system and computing servers. The detector heads hold crystal matrices built from 2 × 2 × 20 mm3 LYSO:Ce crystals readout by Hamamatsu S8550 APD arrays. The APDs are optically coupled to both ends of the 6144 crystals in order to extract the DOI information for each detected event. Each one of 12288 APD's pixels is read and controlled by Application Specific Integrated Circuits water-cooled by an external cooling unit. The Clear-PEM frontend boards innovative design results in a unprecedented integration of the crystal matrices, APDs and ASICs, making Clear-PEM the PET scanner with the highest number of APD pixels ever integrated so far. In this paper, the scanner's main technical characteristics, calibration strategies and the first spectrometric performance evaluation in a clinical environment are presented. The first commissioning results show 99.7% active channels, which, after calibration, have inter-pixel and absolute gain distributions with dispersions of, respectively, 12.2% and 15.3%, demonstrating that despite the large number of channels, the system is uniform. The mean energy resolution at 511 keV is of 15.9%, with a 8.8% dispersion, and the mean CDOI-1 is 5.9%/mm, with a 7.8% dispersion. The coincidence time resolution, at 511 keV, for a energy window between 400 and 600 keV, is 5.2 ns FWHM.

  17. Disaggregated Bundle Methods for Distributed Market Clearing in Power Networks

    OpenAIRE

    Zhang, Yu; Gatsis, Nikolaos; Giannakis, Georgios B.

    2013-01-01

    A fast distributed approach is developed for the market clearing with large-scale demand response in electric power networks. In addition to conventional supply bids, demand offers from aggregators serving large numbers of residential smart appliances with different energy constraints are incorporated. Leveraging the Lagrangian relaxation based dual decomposition, the resulting optimization problem is decomposed into separate subproblems, and then solved in a distributed fashion by the market...

  18. Crowded Trades: An Overlooked Systemic Risk for Central Clearing Counterparties

    OpenAIRE

    Albert J. Menkveld

    2014-01-01

    Counterparty default risk might hamper trade and trigger a financial crisis. The introduction of a central clearing counterparty (CCP) benefits trading but pushes systemic risk into CCP default. Standard risk management strategies at CCPs currently overlook a risk associated with crowded trades. This paper identifies it, measures it, and proposes a margin methodology that accounts for it. The application to actual CCP data illustrates that this hidden risk can become large, in particular at t...

  19. Autophagy and bacterial clearance: a not so clear picture

    OpenAIRE

    Mostowy, Serge

    2012-01-01

    Autophagy, an intracellular degradation process highly conserved from yeast to humans, is viewed as an important defence mechanism to clear intracellular bacteria. However, recent work has shown that autophagy may have different roles during different bacterial infections that restrict bacterial replication (antibacterial autophagy), act in cell autonomous signalling (non-bacterial autophagy) or support bacterial replication (pro-bacterial autophagy). This review will focus on newfound intera...

  20. Clear-Air Propagation Modeling using Parabolic Equation Method

    Directory of Open Access Journals (Sweden)

    V. Kvicera

    2003-12-01

    Full Text Available Propagation of radio waves under clear-air conditions is affected bythe distribution of atmospheric refractivity between the transmitterand the receiver. The measurement of refractivity was carried out onthe TV Tower Prague to access evolution of a refractivity profile. Inthis paper, the parabolic equation method is used in modelingpropagation of microwaves when using the measured data. This paperbriefly describes the method and shows some practical results ofsimulation of microwave propagation using real vertical profiles ofatmospheric refractivity.

  1. Where should I send it? Optimizing the submission decision process.

    Directory of Open Access Journals (Sweden)

    Santiago Salinas

    Full Text Available How do scientists decide where to submit manuscripts? Many factors influence this decision, including prestige, acceptance probability, turnaround time, target audience, fit, and impact factor. Here, we present a framework for evaluating where to submit a manuscript based on the theory of Markov decision processes. We derive two models, one in which an author is trying to optimally maximize citations and another in which that goal is balanced by either minimizing the number of resubmissions or the total time in review. We parameterize the models with data on acceptance probability, submission-to-decision times, and impact factors for 61 ecology journals. We find that submission sequences beginning with Ecology Letters, Ecological Monographs, or PLOS ONE could be optimal depending on the importance given to time to acceptance or number of resubmissions. This analysis provides some guidance on where to submit a manuscript given the individual-specific values assigned to these disparate objectives.

  2. A Web portal for CMS Grid job submission and management

    International Nuclear Information System (INIS)

    We present a Web portal for CMS Grid submission and management. The portal is built using a JBoss application server. It has a three tier architecture; presentation, business logic and data. Bean based business logic interacts with the underlying Grid infrastructure and pre-existing external applications, while the presentation layer uses AJAX to offer an intuitive, functional interface to the back-end. Application data aggregating information from the portal as well as the external applications is persisted to the server memory cache and then to a backend database. We describe how the portal exploits standard, off-the-shelf commodity software together with existing Grid infrastructures in order to facilitate job submission and monitoring for the CMS collaboration. This paper describes the design, development, current functionality and plans for future enhancements of the portal.

  3. Is Clear Lake methylmercury distribution decoupled from bulk mercury loading?

    Science.gov (United States)

    Suchanek, Thomas H; Eagles-Smith, Collin A; Harner, E James

    2008-12-01

    Clear Lake is the site of the abandoned Sulphur Bank Mercury Mine, active periodically from 1873 to 1957, resulting in approximately 100 Mg of mercury (Hg) being deposited into the lake's ecosystem. Concentrations of total (primarily inorganic) Hg (TotHg) in Clear Lake are some of the highest reported worldwide for sediments (up to 4.4 x 10(5) ng/g [ppb dry mass]) and water (up to 4 x 10(-1) microg/L [= ppb]). However, the ratio of methylmercury (MeHg) to TotHg at Clear Lake indicates that the methylation process is mostly decoupled from bulk inorganic Hg loading, with Hg in lower trophic level biota significantly less than anticipated compared with other Hg-contaminated sites worldwide. This may be due to several factors, including: (1) reduced bioavailability of Hg derived from the mine (i.e., cinnabar, metacinnabar, and corderoite), (2) the alkaline nature of the lake water, (3) the shallow depth of the lake, which prevents stratification and subsequent methylation in a stratified hypolimnion, and (4) possible dilution of MeHg by a highly productive system. However, while bulk inorganic Hg loading to the lake may not contribute significantly to the bioaccumulation of Hg, acid mine drainage (AMD) from the mine likely promotes Hg methylation by sulfate-reducing and iron-reducing bacteria, making AMD a vehicle for the production of highly bioavailable Hg. If Clear Lake were deeper, less productive, or less alkaline, biota would likely contain much more MeHg than they do presently. Comparisons of MeHg:TotHg ratios in sediments, water, and biota from sites worldwide suggest that the highest production of MeHg may be found at sites influenced by chloralkali plants, followed by sites influenced by gold and silver mines, with the lowest production of MeHg observed at cinnabar and metacinnabar Hg mines. These data also suggest that the total maximum daily load (TMDL) process for Hg at Clear Lake, as currently implemented to reduce contamination in fishes for the

  4. Interactive Multi-Submission Deposit Workflows for Desktop Applications

    OpenAIRE

    Tarrant, David; Carr, Les; Wade, Alex; Warner, Simeon

    2010-01-01

    Online submission and publishing is the norm for academic researchers. With the pressure on these authors to submit their work to conferences, journals and Institutional Repositories, this leads to de- mands on the author to go through multiple web based interfaces, filling in forms with the same information multiple times before they can sub- mit. At the same time, each of these services in turn will have made pol- icy decisions on what types of format they allow and what templates the conte...

  5. Diretrizes para Autores - Normas de Submissão

    OpenAIRE

    Revista Brasileira de Medicina de Família e Comunidade RBMFC

    2012-01-01

    Objetivo e Política EditorialProcesso de avaliação pelos paresSeções e Tipos de TrabalhosApresentação e Preparo dos ManuscritosSubmissão EletrônicaDeclaração de Autoria e responsabilidade dos autoresExemplo de Declaração de Autoria e ResponsabilidadeÉtica em PesquisaAgradecimentosDúvidas e Esclarecimentos adicionais

  6. Diretrizes para autores - Normas para submissão

    OpenAIRE

    Revista Brasileira de Medicina de Família e Comunidade RBMFC

    2012-01-01

    Objetivo e Política EditorialProcesso de avaliação pelos paresSeções e Tipos de TrabalhosApresentação e Preparo dos ManuscritosSubmissão EletrônicaDeclaração de Autoria e responsabilidade dos autoresExemplo de Declaração de Autoria e ResponsabilidadeÉtica em PesquisaAgradecimentosDúvidas e Esclarecimentos adicionais

  7. NCC Submission to the Commission on Taxation, June 2008

    OpenAIRE

    2008-01-01

    A Commission on Taxation has been established to review the structure, efficiency and appropriateness of the Irish taxation system. The NCC prepared the following submission. It highlights the importance of taxation policy to competitiveness, and calls for further actions to assess how the taxation system can promote the development of the knowledge economy. It also highlights the importance of maintaining Ireland’s competitive labour tax wedge and the need to review property taxation.

  8. 48 CFR 49.303-2 - Submission of inventory disposal schedules.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Submission of inventory... REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS Additional Principles for Cost-Reimbursement Contracts Terminated for Convenience 49.303-2 Submission of inventory disposal schedules. Subject to...

  9. 32 CFR 635.25 - Submission of criminal history data to the CJIS.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS LAW ENFORCEMENT REPORTING Offense Reporting § 635.25 Submission of criminal history data to the CJIS. (a) General. This paragraph establishes procedures for... 32 National Defense 4 2010-07-01 2010-07-01 true Submission of criminal history data to the...

  10. 78 FR 17646 - Agency Information Collection Activities; eZ-Audit: Electronic Submission of Financial Statements...

    Science.gov (United States)

    2013-03-22

    ... Agency Information Collection Activities; eZ-Audit: Electronic Submission of Financial Statements and... notice will be considered public records. Title of Collection: eZ-Audit: Electronic Submission of Financial Statements and Compliance Audits. OMB Control Number: 1845-0072. Type of Review: an extension of...

  11. 48 CFR 49.304-2 - Submission of settlement proposal (fee only).

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Submission of settlement proposal (fee only). 49.304-2 Section 49.304-2 Federal Acquisition Regulations System FEDERAL ACQUISITION... Contracts Terminated for Convenience 49.304-2 Submission of settlement proposal (fee only). The...

  12. 78 FR 5816 - Electronic Study Data Submission; Data Standard Support End Date

    Science.gov (United States)

    2013-01-28

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Electronic Study Data Submission; Data Standard Support End... Act (FDASIA) (Public Law 112- 144), requires electronic submission of drug and biologic...

  13. 48 CFR 252.232-7003 - Electronic submission of payment requests and receiving reports.

    Science.gov (United States)

    2010-10-01

    ... PROVISIONS AND CONTRACT CLAUSES Text of Provisions And Clauses 252.232-7003 Electronic submission of payment... administering the contract for payment has determined, in writing, that electronic submission would be unduly... non-electronic payment requests using the method or methods specified in Section G of the contract....

  14. 47 CFR 65.103 - Procedures for filing rate of return submissions.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Procedures for filing rate of return... CARRIER SERVICES (CONTINUED) INTERSTATE RATE OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Procedures § 65.103 Procedures for filing rate of return submissions. (a) Rate of return submissions...

  15. 76 FR 8371 - Notice Correction; Generic Submission of Technology Transfer Center (TTC) External Customer...

    Science.gov (United States)

    2011-02-14

    ... Transfer Center (TTC) External Customer Satisfaction Surveys (NCI) The Federal Register notice published on... Transfer Center (TTC) External Customer Satisfaction Survey (NCI)'' was submitted with errors. The submission ] is now being presented as a generic submission which will include multiple customer...

  16. 78 FR 70954 - Transport Format for the Submission of Regulatory Study Data; Notice of Pilot Project

    Science.gov (United States)

    2013-11-27

    ... HUMAN SERVICES Food and Drug Administration Transport Format for the Submission of Regulatory Study Data...) transport format for the submission of regulatory study data. The current study data transport format supported by FDA is the SAS Transport (XPORT) version 5 file format. Although XPORT has been a...

  17. 49 CFR 1152.36 - Submission of revenue and cost data.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Submission of revenue and cost data. 1152.36... AND RAIL TRANSPORTATION UNDER 49 U.S.C. 10903 Standards for Determining Costs, Revenues, and Return on Value § 1152.36 Submission of revenue and cost data. The following information shall be submitted...

  18. 46 CFR 560.8 - Submission of decision to the President.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Submission of decision to the President. 560.8 Section... TRADE BETWEEN FOREIGN PORTS § 560.8 Submission of decision to the President. Concurrently with the... Commission shall transmit that decision to the President of the United States who may, within ten days...

  19. A Web Support System for Submission and Handling of Programming Assignments

    DEFF Research Database (Denmark)

    Nørmark, Kurt

    2011-01-01

    Individual submission of programming assignments should be considered in all introductory programming courses. We describe a custom web support system for submission and management of programming assignments in an introductory C programming course. Experience from the first time use of the system...

  20. A Comparison of Electronic and Paper-Based Assignment Submission and Feedback

    Science.gov (United States)

    Bridge, Pete; Appleyard, Rob

    2008-01-01

    This paper presents the results of a study evaluating student perceptions of online assignment submission. 47 students submitted assignments and received feedback via features within the Virtual Learning Environment Blackboard[TM]. The students then completed questionnaires comparing their experience of online submission and feedback with…

  1. 40 CFR 66.43 - Final decision; submission of penalty calculation.

    Science.gov (United States)

    2010-07-01

    ... Agency decision that it is in violation of applicable legal requirements or is not entitled to an... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Final decision; submission of penalty... Requests and Challenges to Notices of Noncompliance § 66.43 Final decision; submission of...

  2. 48 CFR 52.214-34 - Submission of Offers in the English Language.

    Science.gov (United States)

    2010-10-01

    ... the English Language. 52.214-34 Section 52.214-34 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.214-34 Submission of Offers in the English Language. As prescribed in 14.201-6(w), insert the following provision: Submission of Offers in the English Language (APR 1991) Offers...

  3. 40 CFR 26.1303 - Submission of information pertaining to ethical conduct of completed human research.

    Science.gov (United States)

    2010-07-01

    ... ethical conduct of completed human research. 26.1303 Section 26.1303 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL PROTECTION OF HUMAN SUBJECTS Requirements for Submission of Information on the Ethical Conduct of Completed Human Research § 26.1303 Submission of information pertaining...

  4. 78 FR 45167 - Notification of Submission to the Secretary of Agriculture; Pesticides, Agricultural Worker...

    Science.gov (United States)

    2013-07-26

    ... AGENCY 40 CFR Part 170 RIN 2070-AJ22 Notification of Submission to the Secretary of Agriculture...). ACTION: Notification of submission to the Secretary of Agriculture. SUMMARY: This document notifies the... Administrator has forwarded to the Secretary of the United States Department of Agriculture (USDA) a...

  5. 10 CFR 150.19 - Submission to Commission of tritium reports.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Submission to Commission of tritium reports. 150.19... Agreement States § 150.19 Submission to Commission of tritium reports. (a)-(b) (c) Except as specified in... possess tritium shall report promptly to the appropriate NRC Regional Office as shown in appendix D...

  6. 78 FR 10215 - Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB...

    Science.gov (United States)

    2013-02-13

    ... collection on October 17, 2012 (77 FR 63893). 1. Type of submission, new, revision, or extension: Extension... COMMISSION Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB... annually to complete the requirement or request: 59,782 (54,208 hrs. reporting + 1 hr....

  7. 39 CFR 3007.10 - Submission of non-public materials under seal.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Submission of non-public materials under seal. 3007.10 Section 3007.10 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL TREATMENT OF NON-PUBLIC MATERIALS PROVIDED BY THE POSTAL SERVICE § 3007.10 Submission of non-public materials under seal. (a)...

  8. 5 CFR 2604.601 - Electronic posting and submission of annual OGE FOIA report.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Electronic posting and submission of annual OGE FOIA report. 2604.601 Section 2604.601 Administrative Personnel OFFICE OF GOVERNMENT ETHICS... FINANCIAL DISCLOSURE REPORTS Annual OGE FOIA Report § 2604.601 Electronic posting and submission of...

  9. 76 FR 19121 - Notice of Submission of Proposed Information Collection to OMB Multifamily Project Applications...

    Science.gov (United States)

    2011-04-06

    ... collection techniques or other forms of information technology, e.g., permitting electronic submission of... mortgage insurance. Project owners/sponsors may apply for permission to commence construction prior to... Executive Office Building, Washington, DC 20503; e-mail OIRA-Submission@omb.eop.gov fax: 202-395- 5806....

  10. Enabling Successful Submissions of Scientific Data for Preservation and Future Use

    Science.gov (United States)

    Downs, R. R.; Chen, R. S.

    2009-12-01

    Preparing scientific data and research-related information for submission to a scientific data archive or digital repository for long-term preservation and dissemination is a critical task for data stewardship, but can be challenging for those who have produced data initially for their own use. We describe here a data submission system designed to assist data producers in preparing and describing their data in ways that balance the need for comprehensive information about the data with the practicalities of what data producers are willing and able to provide. The system is based on a model for web-based services that enables self-submission and supports the workflow needed for gathering the information required for long-term preservation and use by current and future research, education, and decision-making communities. To inform the design of the system for a range of data types, submissions of both Earth and social science data sets were analyzed to identify successful practices that could be implemented in a self-submission system. We describe these successful data submission practices along with the features of a self-submission system that should help encourage the submission of scientific data by both natural and social scientists.

  11. 40 CFR 725.160 - Submission of health and environmental effects data.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Submission of health and environmental effects data. 725.160 Section 725.160 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Commercial Activities Notification Requirements § 725.160 Submission of health and environmental effects...

  12. 76 FR 45588 - Notice of Submission of Proposed Information Collection to OMB; Innovation of the Day

    Science.gov (United States)

    2011-07-29

    ...: Innovation of the Day. OMB Approval Number: 2528-Pending. Form Numbers: None. Description of the Need for the... URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; Innovation of the Day... subject proposal. ``Innovation of the Day'' is a new online submission and display platform located on...

  13. 40 CFR 60.4121 - Submission of Hg budget permit applications.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Submission of Hg budget permit... Times for Coal-Fired Electric Steam Generating Units Permits § 60.4121 Submission of Hg budget permit applications. (a) Duty to apply. The Hg designated representative of any Hg Budget source required to have...

  14. 40 CFR 24.14 - Scheduling the hearing; pre-hearing submissions by the parties.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Scheduling the hearing; pre-hearing submissions by the parties. 24.14 Section 24.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Hearings on Orders Requiring Corrective Measures § 24.14 Scheduling the hearing; pre-hearing submissions...

  15. Investigation of the Effect of Sport on Submissive Behavior and Communication Skills of High School Students

    Science.gov (United States)

    Abakay, Ugur

    2013-01-01

    This study was carried out to detect the differences in submissive behaviors and communication skills of high school students in terms of sports activities and relationship between communication skills and properties of submissive behavior of high school students who are actively involved in sports activities. In this respect at the study, 728…

  16. 48 CFR 652.232-70 - Payment Schedule and Invoice Submission (Fixed-Price).

    Science.gov (United States)

    2010-10-01

    ... Invoice Submission (Fixed-Price). 652.232-70 Section 652.232-70 Federal Acquisition Regulations System... Clauses 652.232-70 Payment Schedule and Invoice Submission (Fixed-Price). As prescribed in 632.908(a), the contracting officer may insert a clause substantially the same as follows: Payment Schedule and...

  17. 12 CFR Appendix IV to Part 27 - Home Loan Data Submission

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 1 2010-01-01 2010-01-01 false Home Loan Data Submission IV Appendix IV to Part 27 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY FAIR HOUSING HOME LOAN DATA SYSTEM Pt. 27, App. IV Appendix IV to Part 27—Home Loan Data Submission ER21JN94.003...

  18. The Clear Creek Envirohydrologic Observatory: From Vision Toward Reality

    Science.gov (United States)

    Just, C.; Muste, M.; Kruger, A.

    2007-12-01

    As the vision of a fully-functional Clear Creek Envirohydrologic Observatory comes closer to reality, the opportunities for significant watershed science advances in the near future become more apparent. As a starting point to approaching this vision, we focused on creating a working example of cyberinfrastructure in the hydrologic and environmental sciences. The system will integrate a broad range of technologies and ideas: wired and wireless sensors, low power wireless communication, embedded microcontrollers, commodity cellular networks, the internet, unattended quality assurance, metadata, relational databases, machine-to-machine communication, interfaces to hydrologic and environmental models, feedback, and external inputs. Hardware: An accomplishment to date is "in-house" developed sensor networking electronics to compliment commercially available communications. The first of these networkable sensors are dielectric soil moisture probes that are arrayed and equipped with wireless connectivity for communications. Commercially available data logging and telemetry-enabled systems deployed at the Clear Creek testbed include a Campbell Scientific CR1000 datalogger, a Redwing 100 cellular modem, a YA Series yagi antenna, a NP12 rechargeable battery, and a BP SX20U solar panel. This networking equipment has been coupled with Hach DS5X water quality sondes, DTS-12 turbidity probes and MicroLAB nutrient analyzers. Software: Our existing data model is an Arc Hydro-based geodatabase customized with applications for extraction and population of the database with third party data. The following third party data are acquired automatically and in real time into the Arc Hydro customized database: 1) geophysical data: 10m DEM and soil grids, soils; 2) land use/land cover data; and 3) eco-hydrological: radar-based rainfall estimates, stream gage, streamlines, and water quality data. A new processing software for data analysis of Acoustic Doppler Current Profilers (ADCP

  19. Operating experience with electron cloud clearing electrodes at DAFNE

    CERN Document Server

    Zobov, M; Drago, A; Gallo, A; Guiducci, S; Milardi, C; Stella, A; De Santis, S; Demma, T; Raimondi, P

    2013-01-01

    During the current run of an electron-positron collider DAFNE special electrodes for electron cloud suppression have been inserted in all dipole and wiggler magnets of the positron ring. In this paper we discuss the impact of these electrodes on beam dynamics and overall collider performance. In particular we report results of measurements such as e-cloud instabilities growth rate, transverse beam size variation, tune shifts along the bunch train etc. with the electrodes switched on and off that clearly indicate the effectiveness of the electrodes for e-cloud suppression.

  20. Clear Sky Index : Framtagen med enkortsdator och webbkamera

    OpenAIRE

    Enström, Oskar; Klavebäck, Erik; Muhrbeck, Rasmus

    2015-01-01

    A future sustainable society need to rely more on renewable energy sources. One of the most promising alternatives is solar power. However, there are inherent fluctuations accompanied with solar power, for example if the shadow of a cloud blocks the sun light on a whole solar cell it will not produce any power. This will cause problems with connecting the solar panels to the power grid. Clear sky index (CSI) is a measurement of how much of the sky that is covered by clouds, and is a key param...

  1. Optical clearing and multiphoton imaging of paraffin-embedded specimens

    Science.gov (United States)

    Wilson, Jesse W.; Degan, Simone; Fischer, Martin C.; Warren, Warren S.

    2013-02-01

    New labeling, imaging, or analysis tools could provide new retrospective insights when applied to archived, paraffin-embedded samples. Deep-tissue multiphoton microscopy of paraffin-embedded specimens is achieved using optical clearing with mineral oil. We tested a variety of murine tissue specimens including skin, lung, spleen, kidney, and heart, acquiring multiphoton autofluorescence and second-harmonic generation, and pump-probe images This technique introduces the capability for non-destructive 3-dimensional microscopic imaging of existing archived pathology specimens, enabling retrospective studies.

  2. Clear Cell Adenocarcinoma of the Urethra: Review of the Literature

    Directory of Open Access Journals (Sweden)

    Anthony Kodzo-Grey Venyo

    2015-01-01

    Full Text Available Background. Clear cell adenocarcinoma of the urethra (CCAU is extremely rare and a number of clinicians may be unfamiliar with its diagnosis and biological behaviour. Aims. To review the literature on CCAU. Methods. Various internet databases were used. Results/Literature Review. (i CCAU occurs in adults and in women in the great majority of cases. (ii It has a particular association with urethral diverticulum, which has been present in 56% of the patients; is indistinguishable from clear cell adenocarcinoma of the female genital tract but is not associated with endometriosis; and probably does not arise by malignant transformation of nephrogenic adenoma. (iii It is usually, readily distinguished from nephrogenic adenoma because of greater cytological a-typicality and mitotic activity and does not stain for prostate-specific antigen or prostatic acid phosphatase. (iv It has been treated by anterior exenteration in women and cystoprostatectomy in men and at times by radiotherapy; chemotherapy has rarely been given. (v CCAU is aggressive with low 5-year survival rates. (vi There is no consensus opinion of treatment options that would improve the prognosis. Conclusions. Few cases of CCAU have been reported. Urologists, gynaecologists, pathologists, and oncologists should report cases of CCAU they encounter and enter them into a multicentric trial to determine the best treatment options that would improve the prognosis.

  3. A new computational method for reactive power market clearing

    International Nuclear Information System (INIS)

    After deregulation of electricity markets, ancillary services such as reactive power supply are priced separately. However, unlike real power supply, procedures for costing and pricing reactive power supply are still evolving and spot markets for reactive power do not exist as of now. Further, traditional formulations proposed for clearing reactive power markets use a non-linear mixed integer programming formulation that are difficult to solve. This paper proposes a new reactive power supply market clearing scheme. Novelty of this formulation lies in the pricing scheme that rewards transformers for tap shifting while participating in this market. The proposed model is a non-linear mixed integer challenge. A significant portion of the manuscript is devoted towards the development of a new successive mixed integer linear programming (MILP) technique to solve this formulation. The successive MILP method is computationally robust and fast. The IEEE 6-bus and 300-bus systems are used to test the proposed method. These tests serve to demonstrate computational speed and rigor of the proposed method. (author)

  4. DAΦNE Operation with Electron-Cloud-Clearing Electrodes

    Science.gov (United States)

    Alesini, D.; Drago, A.; Gallo, A.; Guiducci, S.; Milardi, C.; Stella, A.; Zobov, M.; De Santis, S.; Demma, T.; Raimondi, P.

    2013-03-01

    The effects of an electron cloud (e-cloud) on beam dynamics are one of the major factors limiting performances of high intensity positron, proton, and ion storage rings. In the electron-positron collider DAΦNE, namely, a horizontal beam instability due to the electron-cloud effect has been identified as one of the main limitations on the maximum stored positron beam current and as a source of beam quality deterioration. During the last machine shutdown in order to mitigate such instability, special electrodes have been inserted in all dipole and wiggler magnets of the positron ring. It has been the first installation all over the world of this type since long metallic electrodes have been installed in all arcs of the collider positron ring and are currently used during the machine operation in collision. This has allowed a number of unprecedented measurements (e-cloud instabilities growth rate, transverse beam size variation, tune shifts along the bunch train) where the e-cloud contribution is clearly evidenced by turning the electrodes on and off. In this Letter we briefly describe a novel design of the electrodes, while the main focus is on experimental measurements. Here we report all results that clearly indicate the effectiveness of the electrodes for e-cloud suppression.

  5. Primary abdominal wall clear cell carcinoma arising from incisional endometriosis

    Institute of Scientific and Technical Information of China (English)

    Burcu Gundogdu; Isin Ureyen; Gunsu Kimyon; Hakan Turan; Nurettin Boran; Gokhan Tulunay; Dilek Bulbul; Taner Turan; M Faruk Kose

    2013-01-01

    A 49 year-old patient with the complaint of a mass located in the caesarean scar was admitted. There was a fixed mass 30í30 mm in diameter with regular contour located at the right corner of the pfannenstiel incision. Computed tomography revealed a (40í50í50) mm solid mass lesion with margins that cannot be distinguished from the uterus, bladder and small intestines and a heterogeneous mass lesion (50í45í55) mm in diameter, located in the right side of the anterior abdominal wall. Cytoreductive surgery including total abdominal hysterectomy and bilateral salpingo-oophorectomy was performed. Final pathology was clear cell carcinoma. Clear cell carcinoma arising from an extraovarian endometriotic focus was diagnosed and the patient received 6 cycles paclitaxel-carboplatin chemotherapy as adjuvant treatment. The patient who was lost to follow-up applied to our clinic 2 years after surgery with a recurrent mass in the left inguinal region. After 3 cycles of chemotherapy, the patient's tumoral mass in the left inguinal region was excised. The result of the pathology was carcinoma metastasis. It is decided that the following treatment of the patient should be palliative radiation therapy. The patient who underwent palliative radiation therapy died of disease after 4 months of the second operation.

  6. Statistical functions and relevant correlation coefficients of clearness index

    Science.gov (United States)

    Pavanello, Diego; Zaaiman, Willem; Colli, Alessandra; Heiser, John; Smith, Scott

    2015-08-01

    This article presents a statistical analysis of the sky conditions, during years from 2010 to 2012, for three different locations: the Joint Research Centre site in Ispra (Italy, European Solar Test Installation - ESTI laboratories), the site of National Renewable Energy Laboratory in Golden (Colorado, USA) and the site of Brookhaven National Laboratories in Upton (New York, USA). The key parameter is the clearness index kT, a dimensionless expression of the global irradiance impinging upon a horizontal surface at a given instant of time. In the first part, the sky conditions are characterized using daily averages, giving a general overview of the three sites. In the second part the analysis is performed using data sets with a short-term resolution of 1 sample per minute, demonstrating remarkable properties of the statistical distributions of the clearness index, reinforced by a proof using fuzzy logic methods. Successively some time-dependent correlations between different meteorological variables are presented in terms of Pearson and Spearman correlation coefficients, and introducing a new one.

  7. APLIKASI SIX SIGMA PADA PRODUK CLEAR FILE DI PERUSAHAAN STATIONARY

    Directory of Open Access Journals (Sweden)

    Desy Emilasari

    2007-01-01

    Full Text Available This paper describes the application of the Six Sigma methods is used in order to improve quality in manufacturing company that produce stationary product. DMAIC approach is utilized to analyze and improve 'Pocket Clear File' product since this product has more variability and defects. Quality improvement also monitor the process that influenced pocket defect in Bag Making, Kami-ire, Karidome, and Pocket after Karidome Inspections section. Determining of Six Sigma project is based in process and defect type in each section. FMEA also gave the recommendation for quality improvement we need to evaluate the final result of the improvement since some of them were not working properly. Abstract in Bahasa Indonesia : Paper ini menggambarkan bagaimana aplikasi metode Six Sigma digunakan untuk melakukan perbaikan kualitas pada perusahaan manufaktur yang memproduksi produk stationary. Pendekatan DMAIC dipakai untuk menganalisa dan melakukan perbaikan produk 'Pocket Clear File' karena tingginya variabilitas dan cacat dibanding produk lain. Perbaikan kualitas juga memperhatikan proses yang mempengaruhi terjadinya cacat pocket pada section Bag Making, Kami-ire, Karidome, dan Pocket after Karidome Inspection. Penentuan proyek Six Sigma didasarkan atas proses dan jenis cacat pada setiap section. Pendekatan FMEA mampu memberi rekomendasi perbaikan kualitas. Evaluasi dari hasil perbaikan penting untuk dilakukan karena beberapa implementasi perbaikan kualitas tidak berjalan sesuai dengan rencana. kata kunci: six sigma, DMAIC, perusahaan stationary.

  8. A giant benign clear cell hidradenoma on the anterior trunk

    Directory of Open Access Journals (Sweden)

    Damlanur Sakiz

    2011-10-01

    Full Text Available Clear cell hidroadenoma (CCA is a uncommon variant of bening cutaneous adnexial tumors. These tumors are clinically asymptomatic, solitary dermal nodules. they occur most frequently on the scalp, face, abdomen and the extremities. Growth is slow and malignant change is rare. 45- year-old woman presented us with a nodule with a central ulceration and a minimal hemoragic discharge on her anterior abdomen wall which had begun 4 years ago as a small nodular asymptomatic lesion. On dermatological examination there was a 6.5x4x5 cm non-tender, soft reddish purple nodule with lobular appearence and ulceration. In the laboratory investigations, all the hematologic and biochemical tests were normal. A CT scan demonstrated a cyctic tumor with lobulated countour with contrast enhancement. The lesion excised totally. In histopathological examination the tumor was composed of biphasic  smaller dark polygonal cells and larger clera cells and coarse nuclear chromatine. There were duct like structures. Immunohistochemical investigation was done for the suspicion of malignancy. Cytoplasm of clear cells and duct like structures showed PAS positive and d-Pas resistant staining. There was a positive reactivity to epithelial membrane antigen and carcinoembrionic antigen. The mitotic index in Ki 67 examination was low. All these findings confirmed the diagnosis of bening CCA. 

  9. Clear cell carcinoid tumor of the distal common bile duct

    Directory of Open Access Journals (Sweden)

    Tsukada Katsuhiko

    2007-01-01

    Full Text Available Abstract Background Carcinoid tumors rarely arise in the extrahepatic bile duct and can be difficult to distinguish from carcinoma. There are no reports of clear cell carcinoid (CCC tumors in the distal bile duct (DBD to the best of our knowledge. Herein, we report a CCC tumor in the DBD and review the literature concerning extrahepatic bile duct carcinoid tumors. Case presentation A 73-old man presented with fever and occult obstructive jaundice. Ultrasonography, computed tomography (CT and magnetic resonance cholangiopancreaticography (MRCP demonstrated a nodular tumor projection in the DBD without regional lymph node swelling. Under suspicion of carcinoma, we resected the head of the pancreas along with 2nd portion duodenectomy and a lymph node dissection. The surgical specimen showed a golden yellow polypoid tumor in the DBD (0.8 × 0.6 × 0.5 cm in size. The lesion was composed of clear polygonal cells arranged in nests and a trabecular pattern. The tumor invaded through the wall into the fibromuscular layer. Immunohistochemical stains showed that neoplastic cells were positive for neuron-specific enolase (NSE, chromogranin A, synaptophysin, and pancreatic polypeptide and negative for inhibin, keratin, CD56, serotonin, gastrin and somatostatin. The postoperative course was uneventful and he is living well without relapse 12 months after surgery. Conclusion Given the preoperative difficulty in differentiating carcinoid from carcinoma, the pancreaticoduodenectomy is an appropriate treatment choice for carcinoid tumors located within the intra-pancreatic bile duct.

  10. Use of Digital Image Technology to 'Clearly' Depict Global Change

    Science.gov (United States)

    Molnia, B. F.; Carbo, C. L.

    2014-12-01

    Earth is dynamic and beautiful. Understanding why, when, how, and how fast its surface changes yields information and serves as a source of inspiration. The artistic use of geoscience information can inform the public about what is happening to their planet in a non-confrontational and apolitical way. While individual images may clearly depict a landscape, photographic comparisons are necessary to clearly capture and display annual, decadal, or century-scale impacts of climate and environmental change on Earth's landscapes. After years of effort to artistically communicate geoscience concepts with unenhanced individual photographs or pairs of images, the authors have partnered to maximize this process by using digital image enhancement technology. This is done, not to manipulate the inherent artistic content or information content of the photographs, but to insure that the comparative photo pairs produced are geometrically correct and unambiguous. For comparative photography, information-rich historical photographs are selected from archives, websites, and other sources. After determining the geographic location from which the historical photograph was made, the original site is identified and eventually revisited. There, the historical photos field of view is again photographed, ideally from the original location. From nearly 250 locations revisited, about 175 pairs have been produced. Every effort is made to reoccupy the original historical site. However, vegetation growth, visibility reduction, and co-seismic level change may make this impossible. Also, inherent differences in lens optics, camera construction, and image format may result in differences in the geometry of the new photograph when compared to the old. Upon selection, historical photos are cleaned, contrast stretched, brightness adjusted, and sharpened to maximize site identification and information extraction. To facilitate matching historical and new images, digital files of each are overlain in

  11. Temporal co-registration for TROPOMI cloud clearing

    Directory of Open Access Journals (Sweden)

    I. Genkova

    2011-10-01

    Full Text Available The TROPOspheric Monitoring Instrument (TROPOMI is planed for launch in 2014 on board of the Sentinel 5 Precursor (S5P and is anticipated to provide high-quality and timely information on the global atmospheric composition for climate and air quality applications. TROPOMI will observe key atmospheric constituents such as ozone, nitrogen dioxide, sulfur dioxide, carbon monoxide, methane, formaldehyde and aerosol properties. The retrieval algorithms for the anticipated products require cloud information on a pixel basis. Most of them will use the cloud properties derived from TROPOMI's own measurements, such as the O2 A-band measurements. However, the methane and the aerosol retrievals require very precise cloud clearing, which is difficult to achieve at the TROPOMI spatial resolution (7 × 7 km2 and without thermal IR measurements. The current payload of the Sentinel 5 Precursor (S-5P does not include a cloud imager, thus it is planned to fly the S5P mission in a constellation with another instrument yielding an accurate cloud mask. The cloud imagery data will be provided by the US NPOESS Preparatory Project (NPP mission which will have the Visible Infrared Imager Radiometer Suite (VIIRS on board (Scalione, 2004. VIIRS will have 22 bands in the VIS and IR spectral ranges, and will deliver data with two spatial resolutions: imagery resolution bands with a nominal pixel size of 370 m at nadir, and moderate resolution bands with nominal pixel size 740 m at nadir. The instrument is combining fine spatial resolution with high-accuracy calibration similar or superior to AVHRR.

    This paper presents results from investigating the temporal co-registration requirements for suitable time differences between the VIIRS measurements of clouds and the TROPOMI methane and aerosol measurements, so that the former could be used for cloud clearing. The temporal co-registration is studied using Meteosat Second Generation (MSG Spinning

  12. Simulating colors of clear and partly cloudy skies.

    Science.gov (United States)

    Gedzelman, Stanley David

    2005-09-20

    A model (SKYCOLOR) is developed that simulates the light and color of the sky and open cloud decks in the vertical plane including the Sun and the observer and animates the changes as the Sun goes down. Model skylight consists of sunbeams that are scattered toward the observer, but depleted by scattering and absorption in the Chappuis bands of ozone. SKYCOLOR includes the Earth's curvature, atmospheric refraction, cloud shadows, and solar eclipses. Scattering is given a wavelength (lambda) dependence of lambda(-4) for air molecules (Rayleigh scattering), lambda(-1) for tropospheric aerosols, and lambda(+1) for volcanic aerosol particles. Multiple scattering is calculated directly in clouds but is parameterized in clear air by decreasing the scattering rates of sunlight and of skylight in the Earth's shadow by 30%. PMID:16201435

  13. The palm oil supply chain, deforestation and peat clearing

    Science.gov (United States)

    Boucher, D. H.

    2013-12-01

    The palm oil industry has expanded rapidly in the last two decades, particularly in Indonesia. A considerable amount of this expansion has been at the expense of forests and peatlands, resulting in considerable greenhouse gas emissions. Now the industry is faced with two new challenges. There is a possible oversupply on the global market due to recent expansion and the time lag between clearing and new production coming on line, which may depress prices considerably. Furthermore, there is increasing pressure to reduce the industry's impact on climate and biodiversity, exemplified by the commitment by the businesses of the Consumer Goods Forum to eliminate deforestation from their supply chains by 2020. This presentation will examine the interaction between these two challenges and its implications for the industry, in both southeast Asia and new regions of expansion, and how this interaction could transform the industry's mode of expansion in the coming decade.

  14. Electricity market clearing with improved dispatch of stochastic production

    DEFF Research Database (Denmark)

    Morales González, Juan Miguel; Zugno, Marco; Pineda, Salvador;

    2014-01-01

    -constrained auction purely based on the least-cost merit order, where stochastic generation enters with its expected production and a low marginal cost; on the other, a counterfactual auction that also accounts for the projected balancing costs using stochastic programming. Although the stochastic clearing procedure...... in some scenarios. Using a bilevel programming framework, we then show that the conventional auction, if combined with a suitable day-ahead dispatch of stochastic producers (generally different from their expected production), can substantially increase market efficiency and emulate the advantageous...... features of the stochastic optimization ideal, while avoiding its major pitfalls. A two-node power system serves as both an illustrative example and a proof of concept. Finally, a more realistic case study highlights the main advantages of a smart day-ahead dispatch of stochastic producers....

  15. Proposal for a project agreement with ISTC - Crystal Clear Collaboration

    CERN Document Server

    2001-01-01

    This document concerns a project agreement with the ISTC entitled "Development of the Detector Production Technology for a New Generation of Positron Emission Tomographs to be used in Medecine and Pharmacology" to be executed in co-operation with the Crystal Clear Collaboration. For the reasons set out in this document, the Finance Committee is invited to agree to the negotiation of a project agreement with ISTC for a total amount of 775 000 US dollars. The European Union party in ISTC will co-fund the project up to a total of 525 000 US dollars. CERN's contribution will not exceed 250 000 US dollars. At the present rate of exchange this is equivalent to approximately 430 000 Swiss francs

  16. All-clear for gourmets: truffles not radioactive

    Science.gov (United States)

    Büntgen, U.; Jäggi, M.; Stobbe, U.; Tegel, W.; Sproll, L.; Eikenberg, J.; Egli, S.

    2016-02-01

    Although ranging among the most expensive gourmet foods, it remains unclear whether Burgundy truffles (Tuber aestivum) accumulate radioactivity at a harmful level comparable to other fungal species. Here, we measure the 137Cs in 82 T. aestivum fruit bodies from Switzerland, Germany, France, Italy, and Hungary. All tested specimens reveal insignificant radiocaesium concentrations, thus providing an all-clear for many truffle hunters and cultivators in large parts of Europe as well as the subsequent chain of dealers and customers from around the world. Our results are particularly relevant in the light of ongoing efforts to cultivate Burgundy truffles, as well as the fact that several forest ecosystems are still highly contaminated with 137Cs, for which mushrooms are one of the main pathways to human diets.

  17. Interpretation of MST radar returns from clear air

    Science.gov (United States)

    Liu, C. H.

    1983-01-01

    The nature of the scattering and reflection mechanisms that give rise to the MST radar echoes from the clear air is essential in the correct interpretation of the data about winds, waves, turbulence and stability in the atmosphere. There are two main aspects: the nature of the targets the radar sees and their generation mechanisms; and the signatures of the radar signals returned from the different targets. Volume scatterings from isotropic or anisotropic turbulence, and partial reflections from horizontally stratified, sharp refractive index gradients are believed the main contributors to radar echoes. Combined effects from all the mechanisms probably produce the observed data. The signature of the echo signals for these different scatterers under realistic experimental conditions should be studied. It is hoped from these studies, the nature of the targets can be better understood, and related to atmospheric dynamic processes.

  18. What can be said can be said clearly

    International Nuclear Information System (INIS)

    The biggest problem in nuclear technology is not the technology itself but the public acceptance. Most people cannot evaluate the radiation risk themselves, so they must trust experts. But, laymen do not understand the jargon of radiation experts, whose language is full of technical terms, unfamiliar units, abbreviations and acronyms etc. After 26 years of experience in radiation protection and public information the author believes that the public has no possibility to leap over the broad communication gap. So, it is the experts who must do it. The author has discussed his communication strategy in his book The Core and the Apple Peel and implemented it in his book Radiation in Everyday Language. He stresses that nothing has been taught if nothing has been learned and claims that everything than can be said can be said clearly. (au)

  19. Endogenous Market-Clearing Prices and Reference Point Adaptation

    Science.gov (United States)

    Dragicevic, Arnaud Z.

    When prices depend on the submitted bids, i.e. with endogenous market-clearing prices in repeated-round auction mechanisms, the assumption of independent private values that underlines the property of incentive-compatibility is to be brought into question; even if these mechanisms provide active involvement and market learning. In its orthodox view, adaptive bidding behavior imperils incentive-compatibility. We relax the assumption of private values' independence in the repeated-round auctions, when the market-clearing prices are made public at the end of each round. Instead of using game-theory learning models, we introduce a behavioral model that shows that bidders bid according to the anchoring-and-adjustment heuristic, which neither ignores the rationality and incentive-compatibility constraints, nor rejects the posted prices issued from others' bids. Bidders simply weight information at their disposal and adjust their discovered value using reference points encoded in the sequential price weighting function. Our model says that bidders and offerers are sincere boundedly rational utility maximizers. It lies between evolutionary dynamics and adaptive heuristics and we model the concept of inertia as high weighting of the anchor, which stands for truthful bidding and high regard to freshly discovered preferences. Adjustment means adaptive rule based on adaptation of the reference point in the direction of the posted price. It helps a bidder to maximize her expected payoff, which is after all the only purpose that matters to rationality. The two components simply suggest that sincere bidders are boundedly rational. Furthermore, by deviating from their anchor in the direction of the public signal, bidders operate in a correlated equilibrium. The correlation between bids comes from the commonly observed history of play and each bidder's actions are determined by the history. Bidders are sincere if they have limited memory and confine their reference point adaptation

  20. 'Towers in the Tempest' Computer Animation Submission

    Science.gov (United States)

    Shirah, Greg

    2008-01-01

    The following describes a computer animation that has been submitted to the ACM/SIGGRAPH 2008 computer graphics conference: 'Towers in the Tempest' clearly communicates recent scientific research into how hurricanes intensify. This intensification can be caused by a phenomenon called a 'hot tower.' For the first time, research meteorologists have run complex atmospheric simulations at a very fine temporal resolution of 3 minutes. Combining this simulation data with satellite observations enables detailed study of 'hot towers.' The science of 'hot towers' is described using: satellite observation data, conceptual illustrations, and a volumetric atmospheric simulation data. The movie starts by showing a 'hot tower' observed by NASA's Tropical Rainfall Measuring Mission (TRMM) spacecraft's three dimensional precipitation radar data of Hurricane Bonnie. Next, the dynamics of a hurricane and the formation of 'hot towers' are briefly explained using conceptual illustrations. Finally, volumetric cloud, wind, and vorticity data from a supercomputer simulation of Hurricane Bonnie are shown using volume techniques such as ray marching.

  1. Astigmatic Outcomes of Temporal versus Nasal Clear Corneal Phacoemulsification

    Directory of Open Access Journals (Sweden)

    Mohammad Pakravan

    2009-04-01

    Full Text Available

    PURPOSE: To compare the astigmatic outcomes of phacoemulsification cataract surgery using temporal versus nasal clear corneal incisions. METHODS: In a clinical trial, consecutive patients with senile cataracts underwent phacoemulsification and implantation of a hydrophobic acrylic foldable intraocular lens through a horizontal clear corneal incision (temporal in right and nasal in left eyes. Outcome measures included keratometric astigmatism and surgically induced astigmatism (SIA calculated by the vector analysis method using the Holladay-Cravy-Koch formula. RESULTS: The nasal and temporal groups consisted of 20 eyes each. Mean preoperative keratometric astigmatism was 0.63±0.48 D and 0.38±0.39 D in the temporal and nasal incision groups respectively (P=0.09. Data on 10 eyes in each study group was available for the six-month analysis. Mean keratometric astigmatism was as follows in the temporal and nasal groups respectively: 0.85±0.47 D versus 1.95±0.45 D at 1 week (P < 0.001, 0.73±0.46 D versus 1.79±0.55 D at 4 weeks (P < 0.001, and 0.63±0.30 D versus 1.05±0.56 D at 6 months (P=0.053 after surgery. SIA at the same follow-up intervals was 0.71±0.20 D versus 1.80±0.22 D (P < 0.001, 0.63±0.20 D versus 1.65±0.31 D (P < 0.001 and 0.26±0.46 D versus 0.92±0.36 D (P=0.002 in the temporal versus nasal incision groups

  2. Childhood to adolescence: dust and gas clearing in protoplanetary disks

    Science.gov (United States)

    Brown, Joanna Margaret

    Disks are ubiquitous around young stars. Over time, disks dissipate, revealing planets that formed hidden by their natal dust. Since direct detection of young planets at small orbital radii is currently impossible, other tracers of planet formation must be found. One sign of disk evolution, potentially linked to planet formation, is the opening of a gap or inner hole in the disk. In this thesis, I have identified and characterized several cold disks with large inner gaps but retaining massive primordial outer disks. While cold disks are not common, with ~5% of disks showing signs of inner gaps, they provide proof that at least some disks evolve from the inside-out. These large gaps are equivalent to dust clearing from inside the Earth's orbit to Neptune's orbit or even the inner Kuiper belt. Unlike more evolved systems like our own, the central star is often still accreting and a large outer disk remains. I identified four cold disks in Spitzer 5-40 μm spectra and modeled these disks using a 2-D radiative transfer code to determine the gap properties. Outer gap radii of 20-45 AU were derived. However, spectrophotometric identification is indirect and model-dependent. To validate this interpretation, I observed three disks with a submillimeter interferometer and obtained the first direct images of the central holes. The images agree well with the gap sizes derived from the spectrophotometry. One system, LkH&alpha 330, has a very steep outer gap edge which seems more consistent with gravitational perturbation rather than gradual processes, such as grain growth and settling. Roughly 70% of cold disks show CO v=1&rarr 0 gas emission from the inner 1 AU and therefore are unlikely to have evolved due to photoevaporation. The derived rotation temperatures are significantly lower for the cold disks than disks without gaps. Unresolved (sub)millimeter photometry shows that cold disks have steeper colors, indicating that they are optically thin at these wavelengths, unlike

  3. Digital histologic images: practical pointers for successful electronic submission to biomedical journals.

    Science.gov (United States)

    Gruber, H E; Hanley, E N; Sun, Y

    2009-12-01

    The advent of digital imaging and online submission of manuscripts has created new challenges for authors using histological images. Digital images are used routinely in today's histology research lab and authors must prepare illustrations that meet standards for resolution, color modes, image size, and digital file types for successful online submission to biomedical journals. Because authors may not be familiar with these requirements, our objective here is to present practical guidelines and information for successful image submission online. Ethical issues related to digital imaging and other current topics also are discussed with reference to available online resources. PMID:19418314

  4. Theses E-Submission Tool at the National Technical University of Athens

    OpenAIRE

    Κουλούρης, Αλέξανδρος; Αναγνωστόπουλος, Άγγελος

    2010-01-01

    Purpose – This paper’s aim it to analyze added value that the theses e-submission system (tool) gave to the NTUA IR service. Design/methodology/approach – The paper describes the e-submission tool, its procedures and evaluates its use. Findings – The tool improved the IR service, which can be certified by the continuing evaluation process. This process produced the following main results: the automated batch importing feature should be integrated into the e-submission system;...

  5. The letter of submission: avoiding the promotional genre

    DEFF Research Database (Denmark)

    Shaw, Philip; Okamura, Akiko

    1998-01-01

    Functionally the letter of submission accompanying an article submitted to a journal is promotional, but it does not have the form one would expect from e.g. Bhatia 1993. Instead it is extremely brief and uninformative. This reflects the so-called Utilitarian Discourse which is a shared feature of...... American culture and the subculture of science. Research published elsewhere (Okamura and Shaw 1999, ESPJ) shows that neither native speakers of English nor non-natives who were not practising scientists could produce the appropriate genre, while NNS scientists produced texts which only deviated slightly...

  6. Background submission to the Royal Commission on Nuclear Power Generation

    International Nuclear Information System (INIS)

    The Royal Commission on Nuclear Power Generation in New Zealand is required to inquire into and report upon the likely consequences of a nuclear power programme. The New Zealand Electricity Department would have prime responsibilty for implementing the construction, operation and maintenance of nuclear power plants should the need be established and should this be acceptable to the Government. In this submission the Department has attempted to present the issues raised by the introduction of nuclear power in relatively simple terms on the assumption that elaboration can be provided later if necessary

  7. Bridge Pressure Flow Scour at Clear Water Threshold Condition

    Institute of Scientific and Technical Information of China (English)

    GUO Junke; KERENYI Kornel; PAGAN-ORTIZ Jorge E; FLORA Kevin

    2009-01-01

    Bridge pressure flow scour at clear water threshold condition is studied theoretically and experimentally. The flume experiments reveal that the measured scour profiles under a bridge are more or less 2-dimensional; all the measured scour profiles can be described by two similarity equations, where the horizontal distance is scaled by the deck width while the local scour by the maximum scour depth; the maximum scour position is located just under the bridge about 15% deck width from the downstream deck edge; the scour begins at about one deck width upstream the bridge while the deposition occurs at about 2.5 deck widths downstream the bridge; and the maximum scour depth decreases with increas-ing sediment size, but increases with deck inundation. The theoretical analysis shows that: bridge scour can be divided into three cases, i.e. downstream unsubmerged, partially submerged, and totally submerged. For downstream unsubmerged flows, the maximum bridge scour depth is an open-channel problem where the conventional methods in terms of critical velocity or bed shear stress can be applied; for partially and totally submerged flows, the equilibrium maximum scour depth can be described by a scour and an inundation similarity number, which has been confirmed by experiments with two decks and two sediment sizes. For application, a design and field evaluation procedure with examples is presented, including the maximum scour depth and scour profile.

  8. Vaginal clear cell carcinoma in a Japanese Black cow.

    Science.gov (United States)

    Michishita, Masaki; Hori, Makito; Nakahira, Rei; Takahashi, Kimimasa

    2016-06-01

    During artificial insemination of an 18-year-old female Japanese Black cow, a mass that was of a hen's egg size was found in the vagina. On necropsy, the firm mass, measuring approximately 3.5 × 3.5 × 3.0 cm, was located at the superior region of the vagina. The cut surface of the mass was gray-white in color with occasional necrotic or hemorrhagic areas. Histologically, the mass was composed of tumor cells arranged in solid nests of various sizes with an occasional tubular structure separated by a delicate fibrovascular stroma. The tumor cells had a hypochromatic nucleus and abundant, faintly eosinophilic cytoplasm. The tumor cells contained diastase-sensitive periodic acid-Schiff positive granules. Immunohistochemically, tumor cells were positive for cytokeratin AE1/AE3, CAM5.2 and carcinoembryonic antigen, but not for vimentin, p63, estrogen receptor-α, progesterone receptor, α-smooth muscle actin, neuron-specific enolase, S-100 protein and chromogranin A. On the basis of these findings, the tumor was diagnosed as a clear cell carcinoma of the vagina. PMID:26852732

  9. Clear cell sarcoma of the kidney in childhood

    International Nuclear Information System (INIS)

    Purpose: To demonstrate clear sarcoma of the kidney (CCSK) imaging diagnosis in an infant hospital, its incidence in childhood and its correlation to the prevalent malignant renal pathology. Material and methods: We retrospectively reviewed 12 patients with histological CCSK diagnosis, examined in our hospital from July 1987 to May 2000. We analysed the clinical findings, we used diagnostic methods and histopathological characteristics, and assessed clinical and radiographic aspects and its differences with Wilms tumour. Results: There was higher incidence in males (4:1). Patient's age ranged from 15 moths to 14 years. All patients had a palpable abdominal mass. Arterial hypertension and hematuria was present in 25% and 16% of the cases. In 6 patients the renal tumour exceeded the middle abdominal line. Ultrasonography revealed: unilateral heterogeneous mass, with hypoechoic areas (necrosis), cystic appearance was identified in 2 cases, calcifications in 2 cases and 1 case showed inferior vena cava thrombosis. Two patients already showed lung metastases at the time of admittance in our institution. Computed Tomography (CT) supported sonographic findings. During clinical evolution metastases were confirmed in 8 patients (bone, lung and testicles) and local relapse in one. Conclusion: CCKS represented 0.5% of renal malignant tumours treated in our hospital and diagnosis was only achieved through pathological anatomy, since no clinical-radiographic sign is pathognomonic to allow a distinction from Wilms tumour. Despite its low incidence, this malignant neoplasm should be considered in differential diagnosis. (author)

  10. MR imaging of clear cell carcinoma of the ovary

    International Nuclear Information System (INIS)

    Magnetic resonance imaging findings are reported for 12 pathologically proven lesions of clear cell carcinoma (CCC) of the ovary in 11 women (mean age 50 years). T1- and T2-weighted MR images were obtained in all patients, and gadolinium-enhanced MR images were obtained in 9. The mean diameter of the tumors was 13 cm. Seven patients presented with stage-I tumors. All 12 lesions consisted of cystic masses with solid protrusions occurring in 10 and solid masses in 2. The cysts were unilocular in 9 lesions and multilocular in 1. In four lesions, the cysts displayed with high intensity on T1-weighted images. Round solid protrusions were identified in 8 lesions. In 5 lesions, the number of protrusions was only a few. The solid portions of 5 masses had slightly high-intensity regions on T1-weighted images. The number of patients with ascites was three. Magnetic resonance imaging of CCC usually shows a unilocular large cyst with solid protrusions, which are often round and few in number. Such MR imaging findings suggest malignant tumor but are not specific. (orig.)

  11. The epigenetic landscape of clear-cell renal cell carcinoma

    Directory of Open Access Journals (Sweden)

    Katarzyna Kluzek

    2015-05-01

    Full Text Available Clear cell renal cell carcinoma (ccRCC is the most common subtype of all kidney tumors. During the last few years, epigenetics has emerged as an important mechanism in ccRCC pathogenesis. Recent reports, involving large-scale methylation and sequencing analyses, have identified genes frequently inactivated by promoter methylation and recurrent mutations in genes encoding chromatin regulatory proteins. Interestingly, three of detected genes (PBRM1, SETD2 and BAP1 are located on chromosome 3p, near the VHL gene, inactivated in over 80% ccRCC cases. This suggests that 3p alterations are an essential part of ccRCC pathogenesis. Moreover, most of the proteins encoded by these genes cooperate in histone H3 modifications. The aim of this review is to summarize the latest discoveries shedding light on deregulation of chromatin machinery in ccRCC. Newly described ccRCC-specific epigenetic alterations could potentially serve as novel diagnostic and prognostic biomarkers and become an object of novel therapeutic strategies.

  12. Nondural-based lumbar clear cell meningioma. Case report.

    Science.gov (United States)

    Holtzman, R N; Jormark, S C

    1996-02-01

    This 32-year-old man had noticed right leg pain for 4 years and developed classic right sciatica after heavy lifting, followed by episodes of buckling of both legs 1 month prior to admission. His medical history included congenital left abducens palsy. Examination revealed a right Lasègue's sign and Fajersztajn's sign with mild weakness of the right extensor hallucis longus. Magnetic resonance imaging revealed a 1.5 x 2.0-cm enhancing intradural lesion at the L3-4 level. Following laminectomy of L-3 and L-4 and intradural exposure, the tumor was found to be draped loosely by the roots of the cauda equina and attached to a single root without any adherence to dura. Transection of the adherent fascicles and typical microdissection of arachnoidal filaments permitted its complete removal without violation of the capsule, allowing the preservation of a large fascicle. The patient's recovery was uneventful. Postoperatively, a mild right lateral foot hypalgesia and diminution of the right ankle jerk implicated the S-1 root. Histological and immunohistochemical analyses diagnosed the specimen as a clear cell meningioma. PMID:8592230

  13. Night sky luminance under clear sky conditions: Theory vs. experiment

    Science.gov (United States)

    Kocifaj, Miroslav

    2014-05-01

    Sky glow is caused by both natural phenomena and factors of anthropogenic origin, and of the latter ground-based light sources are the most important contributors for they emit the spatially linked spectral radiant intensity distribution of artificial light sources, which are further modulated by local atmospheric optics and perceived as the diffuse light of a night sky. In other words, sky glow is closely related to a city's shape and pattern of luminaire distribution, in practical effect an almost arbitrary deployment of random orientation of heterogeneous electrical light sources. Thus the luminance gradation function measured in a suburban zone or near the edges of a city is linked to the City Pattern or vice versa. It is shown that clear sky luminance/radiance data recorded in an urban area can be used to retrieve the bulk luminous/radiant intensity distribution if some a-priori information on atmospheric aerosols is available. For instance, the single scattering albedo of aerosol particles is required under low turbidity conditions, as demonstrated on a targeted experiment in the city of Frýdek-Mistek. One of the main advantages of the retrieval method presented in this paper is that the single scattering approximation is satisfactorily accurate in characterizing the light field near the ground because the dominant contribution to the sky glow has originated from beams propagated along short optical paths.

  14. Clear antismudge unimolecular coatings of diblock copolymers on glass plates.

    Science.gov (United States)

    Macoretta, Danielle; Rabnawaz, Muhammad; Grozea, Claudia M; Liu, Guojun; Wang, Yu; Crumblehulme, Alison; Wyer, Martin

    2014-12-10

    Two poly[3-(triisopropyloxysilyl)propyl methacrylate]-block-poly[2-(perfluorooctyl)ethyl methacrylate] (PIPSMA-b-PFOEMA) samples and one poly(perfluoropropylene oxide)-block-poly-[3-(triisopropyloxysilyl)propyl methacrylate] (PFPO-b-PIPSMA) sample were synthesized, characterized, and used to coat glass plates. These coatings were formed by evaporating a dilute polymer solution containing HCl, which catalyzed PIPSMA's sol-gel chemistry. Polymer usage was minimized by targeting at diblock copolymer unimolecular (brush) layers that consisted of a sol-gelled grafted PIPSMA layer and an oil- and water-repellant fluorinated surface layer. Investigated is the effect of varying the catalyst amount, polymer amount, as well as block copolymer type and composition on the structure, morphology, and oil- and water-repellency of the coatings. Under optimized conditions, the prepared coatings were optically clear and resistant to writing by a permanent marker. The marker's trace was the faintest on PFPO-b-PIPSMA coatings. In addition, the PFPO-b-PIPSMA coatings were far more wear-resistant than the PIPSMA-b-PFOEMA coatings. PMID:25399630

  15. Genetic mutations associated with metastatic clear cell renal cell carcinoma

    Science.gov (United States)

    Wu, Qingjian; Li, Fengjie; Zhao, Jiang; Wu, Kaijin; Qu, Cunye; Chen, Yibu; Li, Meng; Chen, Xuelian; Stucky, Andres; Zhong, Jiangjian; Li, Longkun; Zhong, Jiang F.

    2016-01-01

    Metastasis is the major cause of death among cancer patients, yet early detection and intervention of metastasis could significantly improve their clinical outcomes. We have sequenced and analyzed RNA (Expression) and DNA (Mutations) from the primary tumor (PT), tumor extension (TE) and lymphatic metastatic (LM) sites of patients with clear cell renal cell carcinoma (CCRCC) before treatment. Here, we report a three-nucleotide deletion near the C-region of Plk5 that is specifically associated with the lymphatic metastasis. This mutation is un-detectable in the PT, becomes detectable in the TE and dominates the LM tissue. So while only a few primary cancer cells carry this mutation, the majority of metastatic cells have this mutation. The increasing frequency of this mutation in metastatic tissue suggests that this Plk5 deletion could be used as an early indicator of CCRCC metastasis, and be identified by low cost PCR assay. A large scale clinical trial could reveal whether a simple PCR assay for this mutation at the time of nephrectomy could identify and stratify high-risk CCRCC patients for treatments. PMID:26908440

  16. Vertical velocity structure and geometry of clear air convective elements

    Science.gov (United States)

    Rowland, J. R.; Arnold, A.

    1975-01-01

    The paper discusses observations of individual convective elements with a high-power narrow-beam scanning radar, an FM-CW radar, and an acoustic sounder, including the determination of the vertical air velocity patterns of convective structures with the FM-CW radar and acoustic sounder. Data are presented which link the observed velocity structure and geometrical patterns to previously proposed models of boundary layer convection. It is shown that the high-power radar provides a clear three-dimensional picture of convective cells and fields over a large area with a resolution of 150 m, where the convective cells are roughly spherical. Analysis of time-height records of the FM-CW radar and acoustic sounder confirms the downdraft-entrainment mechanism of the convective cell. The Doppler return of the acoustic sounder and the insect-trail slopes on FM-CW radar records are independent but redundant methods for obtaining the vertical velocity patterns of convective structures.

  17. Activities of RAHP and problems to be cleared towards commercialization

    International Nuclear Information System (INIS)

    Research Association of HTGR Plant (RAHP) is the sole research association on HTGR Plants in industrial sector of Japan since its establishment in 1985. Activities in these years were to analyze world R and D trends, to set-up fundamental development strategies, and to incorporate the study results into actions towards commercialization of HTGR. RAHP is now mainly investigating fuel cycle aspects and development programs of small modular reactors, such as US-Russian GT-MHR and South African PBMR. Conclusions obtained through the activities so far are: (a) From view points of effective use of energies and reduction of environmental impacts in global scale, development of nuclear power is essential, and that of HTGR is desirable in particular, because of its very highly inherent safety and feasibility of high temperature heat utilizations. The role of HTGR is inter-complementary with those of LWR and FBR. (b) Future subjects and problems to be cleared towards commercializing HTGR are: (1) safety, technical and economical demonstrations, including inherent safety, fuel integrity as key of the safety, gas turbine cycle, high temperature system performances, etc.; (2) acceptance of safety design concept, and preparation for its evaluation and licensing. (c) Construction of demonstration plant(s) as a total system, through effective international cooperation, such as internationally common or sharing development on basic machinery systems between GT-MHR and PBMR Programs, becomes most significant. (author)

  18. DAФNE Operation with Electron-Cloud-Clearing Electrodes

    CERN Document Server

    Alesini, D; Gallo, A; Guiducci, S; Milardi, C; Stella, A; Zobov, Mikhail; De Santis, S; Demma, Theo; Raimondi, P

    2013-01-01

    The effects of an electron cloud (e-cloud) on beam dynamics are one of the major factors limiting performances of high intensity positron, proton, and ion storage rings. In the electron-positron collider DAΦNE, namely, a horizontal beam instability due to the electron-cloud effect has been identified as one of the main limitations on the maximum stored positron beam current and as a source of beam quality deterioration. During the last machine shutdown in order to mitigate such instability, special electrodes have been inserted in all dipole and wiggler magnets of the positron ring. It has been the first installation all over the world of this type since long metallic electrodes have been installed in all arcs of the collider positron ring and are currently used during the machine operation in collision. This has allowed a number of unprecedented measurements (e-cloud instabilities growth rate, transverse beam size variation, tune shifts along the bunch train) where the e-cloud contribution is clearly eviden...

  19. Clearing the way for reducing emissions from tropical deforestation

    International Nuclear Information System (INIS)

    Carbon emissions from tropical deforestation account for about 25% of all anthropogenic carbon dioxide emissions but cannot be credited under current climate change agreements. In the discussions around the architecture of the post-2012 climate regime, the possibility of including credits for reduced emissions from deforestation arises. The paper reviews two approaches for this, compensated reductions (CR) as proposed by Santilli et al. and the Joint Research Centre proposal that combine voluntary commitments by non-Annex I countries to reduce emissions from deforestation with carbon market financing. Both approaches have the clear advantages of simplicity and the possibility of fitting to an evolving greenhouse gas emission reduction regime. The authors consider the strengths and limitations of each proposal and build upon them to address several implementation challenges and options for improvement. Given the urgency of avoiding dangerous climate change, the timely development of technically sound, politically acceptable, cost-effective and practicable measures to reduce emissions from deforestation and forest degradation is essential. These two approaches take us a step closer to this goal, but they need to be refined rapidly to enable this goal to be realised

  20. NOAA AVHRR Clear-Sky Products over Oceans (ACSPO): Sea Surface Temperature, Clear Sky Radiances, and Aerosol Optical Depth for the Global Ocean, 2011 - present (NCEI Accession 0072979)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The AVHRR Clear-Sky Processor over Oceans, jointly developed between NESDIS STAR and OSDPD, produces AVHRR clear-sky products over oceans. ACSPO generates output...

  1. 76 FR 54824 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2011-09-02

    ... COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule... Generic CUSIP Number. Fixed Income Clearing Corporation, Government Securities Division Rulebook, Rule 1...-backed security or securities issued by Ginnie Mae. Fixed Income Clearing Corporation,...

  2. Extent and content of data for regulatory submissions: First-in-human and marketing authorization--Viewpoint of US industry.

    Science.gov (United States)

    Harris, Ian Ross

    2015-09-01

    The amount and type of data in regulatory submissions increases dramatically from the first-in-human clinical trials application through to the extensive dossier that is required for marketing authorization. The Pharmaceuticals and Biotechnology industries are very familiar with the requirements and expectations of Health Authorities for small molecule and biologics, but have limited experience for cell-based therapies. Fortunately, the United States Food and Drug Administration (FDA) and European Medicines agency (EMA) Committee for Advanced Therapies (CAT) have considerable experience in regulating cell therapies and have provided extensive Guidance documents for developers. The Agencies offers advice to Sponsors through a variety of meetings. However, it is incumbent on the Sponsor to understand the regulations, interpret the Guidance documents and formulate clear company positions to enable the Agency to provide clear feedback. It is important for Sponsors to understand the factors that are critical for the safety and efficacy of their product and to demonstrate to the Health Authorities that they have a control strategy that ensures safety and efficacy during all stages of development. The focus of this paper is to describe some of the challenges for the chemistry manufacturing and controls (CMC) for cell therapies being development internationally. PMID:26088904

  3. Clear cell urothelial carcinoma of the urinary bladder: a case report and review of the literature

    OpenAIRE

    Knez, Virginia M; Barrow, Willis; Lucia, M. Scott; Wilson, Shandra; La Rosa, Francisco G.

    2014-01-01

    Introduction The occurrence of clear cell tumors in the bladder is not uncommon. Clear cell dysplasia is well-described and characterized by focal replacement of transitional mucosa by cells with abundant clear cytoplasm, nuclear enlargement, and a granular chromatin pattern. Clear cells can also be seen in clear cell adenocarcinoma, which is rare, comprising 0.5% to 2.0% of the reported bladder carcinomas. Other clear cell tumors found in the bladder to be considered in the differential diag...

  4. Do Clear Cell Papillary Renal Cell Carcinomas Have Malignant Potential?

    Science.gov (United States)

    Diolombi, Mairo L; Cheng, Liang; Argani, Pedram; Epstein, Jonathan I

    2015-12-01

    There have been no recurrences or metastases of clear cell papillary renal cell carcinoma (CCPRCC) in 268 reported cases with follow-up in the English-language literature. We identified all our cases of CCPRCC (1990 to 2013), reviewing all cases that preceded the formal designation of the entity. Immunohistochemical stains were performed on 32 cases during their initial workup. In addition, stains for carbonic anhydrase IX and cytokeratin 7 were performed on 2 cases, one with atypical follow-up and the other with a more compact morphology, although not performed initially. An extended panel with AMACR, CD10, and renal cell carcinoma (RCC) was added to the case with atypical follow-up. Fluorescence in situ hybridization for chromosomes 3p, 7, and 17 was performed on the latter case and on another clinically presumed metastatic tumor. In classic cases, immunohistochemical staining was not performed. Fifty-eight patients (31 women; 27 men) with follow-up data were included in our study; 39 cases were from our consult service. The patients' ages ranged from 36 to 83 years. Thirty-five patients had cystic or partially cystic lesions; 6 tumors were multifocal, 3 of which were bilateral. The majority (53 patients; 91.4%) presented with stage pT1 disease (size range, 0.2 to 8 cm), 2 patients presented with pT2 disease (8.5 and 10.3 cm), 1 patient presented with pT3 disease (6.5 cm sarcomatoid RCC focally extending out of the kidney), and pathologic stage was unavailable in 2 cases. Treatment consisted of 29 partial nephrectomies, 26 radical nephrectomies, 2 cryoablations, and 1 cyst ablation. The resection margins were negative in all but one case, with this case disease free after a 26-month period. Two patients had intraoperative tumor disruption and were disease free at 9 and 34 months. Five patients had synchronous ipsilateral renal cell carcinomas (non-CCPRCC). Mean follow-up time was 21 months (range, 1 to 175 mo), with all but 3 patients having no evidence of

  5. Gene expression profile of renal cell carcinoma clear cell type

    Directory of Open Access Journals (Sweden)

    Marcos F. Dall’Oglio

    2010-08-01

    Full Text Available PURPOSE: The determination of prognosis in patients with renal cell carcinoma (RCC is based, classically, on stage and histopathological aspects. The metastatic disease develops in one third of patients after surgery, even in localized tumors. There are few options for treating those patients, and even the new target designed drugs have shown low rates of success in controlling disease progression. Few studies used high throughput genomic analysis in renal cell carcinoma for determination of prognosis. This study is focused on the identification of gene expression signatures in tissues of low-risk, high-risk and metastatic RCC clear cell type (RCC-CCT. MATERIALS AND METHODS: We analyzed the expression of approximately 55,000 distinct transcripts using the Whole Genome microarray platform hybridized with RNA extracted from 19 patients submitted to surgery to treat RCC-CCT with different clinical outcomes. They were divided into three groups (1 low risk, characterized by pT1, Fuhrman grade 1 or 2, no microvascular invasion RCC; (2 high risk, pT2-3, Fuhrman grade 3 or 4 with, necrosis and microvascular invasion present and (3 metastatic RCC-CCT. Normal renal tissue was used as control. RESULTS: After comparison of differentially expressed genes among low-risk, high-risk and metastatic groups, we identified a group of common genes characterizing metastatic disease. Among them Interleukin-8 and Heat shock protein 70 were over-expressed in metastasis and validated by real-time polymerase chain reaction. CONCLUSION: These findings can be used as a starting point to generate molecular markers of RCC-CCT as well as a target for the development of innovative therapies.

  6. DISCRIMINATING BETWEEN CLOUDY, HAZY, AND CLEAR SKY EXOPLANETS USING REFRACTION

    International Nuclear Information System (INIS)

    We propose a method to distinguish between cloudy, hazy, and clear sky (free of clouds and hazes) exoplanet atmospheres that could be applicable to upcoming large aperture space- and ground-based telescopes such as the James Webb Space Telescope (JWST) and the European Extremely Large Telescope (E-ELT). These facilities will be powerful tools for characterizing transiting exoplanets, but only after a considerable amount of telescope time is devoted to a single planet. A technique that could provide a relatively rapid means of identifying haze-free targets (which may be more valuable targets for characterization) could potentially increase the science return for these telescopes. Our proposed method utilizes broadband observations of refracted light in the out-of-transit spectrum. Light refracted through an exoplanet atmosphere can lead to an increase of flux prior to ingress and subsequent to egress. Because this light is transmitted at pressures greater than those for typical cloud and haze layers, the detection of refracted light could indicate a cloud- or haze-free atmosphere. A detection of refracted light could be accomplished in <10 hr for Jovian exoplanets with JWST and <5 hr for super-Earths/mini-Neptunes with E-ELT. We find that this technique is most effective for planets with equilibrium temperatures between 200 and 500 K, which may include potentially habitable planets. A detection of refracted light for a potentially habitable planet would strongly suggest the planet was free of a global cloud or haze layer, and therefore a promising candidate for follow-up observations

  7. MET Inhibition in Clear Cell Renal Cell Carcinoma

    Science.gov (United States)

    Xie, Zuoquan; Lee, Young H.; Boeke, Marta; Jilaveanu, Lucia B.; Liu, Zongzhi; Bottaro, Donald P.; Kluger, Harriet M.; Shuch, Brian

    2016-01-01

    Background: Clear cell renal cell carcinoma (ccRCC) is the most lethal form of kidney cancer. Small molecule VEGFR inhibitors are widely used but are not curative and various resistance mechanisms such as activation of the MET pathway have been described. Dual MET/VEGFR2 inhibitors have recently shown clinical benefit but limited preclinical data evaluates their effects in ccRCC. Methods: An interrogation of the Cancer Genome Atlas (TCGA) dataset was performed to evaluate oncogenic alterations in the MET/VEGFR2 pathway. We evaluated the in vitro effects of Cabozantinib, a dual MET/VEGFR2 inhibitor, using a panel of ccRCC cell lines. Drug effects of cell viability and proliferation, migration, cell scatter, anchorage independent growth, and downstream MET/VEGFR2 signaling pathways were assessed. Results: Twelve percent of TCGA cases had possible MET/HGF oncogenic alterations with co-occurrence noted (p<0.001). MET/HGF altered cases had worse overall survival (p=0.044). Cabozantinib was a potent inhibitor of MET and VEGFR2 in vitro in our cell line panel. PI3K, MAPK and mTOR pathways were also suppressed by cabozantinib, however the effects on cell viability in vitro were modest. At nanomolar concentrations of cabozantinib, HGF-stimulated migration, invasion, cellular scattering and soft agar colony formation were inhibited. Conclusions: We provide further preclinical rationale for dual MET/VEGFR2 inhibition in ccRCC. While the MET pathway is implicated in VEGFR resistance, dual inhibitors may have direct anti-tumor effects in a patient subset with evidence of MET pathway involvement. Cabozantinib is a potent dual MET/VEGFR2 inhibitor, significantly inhibits cell migration and invasion in vitro and likely has anti-angiogenic effects similar to other VEGFR tyrosine kinase inhibitors. Future work involving in vivo models will be useful to better define mechanisms of potential anti-tumor activity. PMID:27390595

  8. Effect of mechanical optical clearing on near-infrared spectroscopy.

    Science.gov (United States)

    Idelson, Christopher R; Vogt, William C; King-Casas, Brooks; LaConte, Stephen M; Rylander, Christopher G

    2015-08-01

    Near-infrared Spectroscopy (NIRS) is a broadly utilized technology with many emerging applications including clinical diagnostics, sports medicine, and functional neuroimaging, to name a few. For functional brain imaging NIR light is delivered at multiple wavelengths through the scalp and skull to the brain to enable spatial oximetry measurements. Dynamic changes in brain oxygenation are highly correlated with neural stimulation, activation, and function. Unfortunately, NIRS is currently limited by its low spatial resolution, shallow penetration depth, and, perhaps most importantly, signal corruption due to light interactions with superficial non-target tissues such as scalp and skull. In response to these issues, we have combined the non-invasive and rapidly reversible method of mechanical tissue optical clearing (MOC) with a commercially available NIRS system. MOC utilizes a compressive loading force on tissue, causing the lateral displacement of blood and water, while simultaneously thinning the tissue. A MOC-NIRS Breath Hold Test displayed a ∼3.5-fold decrease in the time-averaged standard deviation between channels, consequentially promoting greater channel agreement. A Skin Pinch Test was implemented to negate brain and muscle activity from affecting the recorded signal. These results displayed a 2.5-3.0 fold increase in raw signal amplitude. Existing NIRS instrumentation has been further integrated within a custom helmet device to provide a uniform force distribution across the NIRS sensor array. These results showed a gradual decrease in time-averaged standard deviation among channels with an increase in applied pressure. Through these experiments, and the development of the MOC-NIRS helmet device, MOC appears to provide enhancement of NIRS technology beyond its current limitations. PMID:26041069

  9. DISCRIMINATING BETWEEN CLOUDY, HAZY, AND CLEAR SKY EXOPLANETS USING REFRACTION

    Energy Technology Data Exchange (ETDEWEB)

    Misra, Amit K.; Meadows, Victoria S. [Astronomy Department, University of Washington, Seattle, WA 98195 (United States)

    2014-11-01

    We propose a method to distinguish between cloudy, hazy, and clear sky (free of clouds and hazes) exoplanet atmospheres that could be applicable to upcoming large aperture space- and ground-based telescopes such as the James Webb Space Telescope (JWST) and the European Extremely Large Telescope (E-ELT). These facilities will be powerful tools for characterizing transiting exoplanets, but only after a considerable amount of telescope time is devoted to a single planet. A technique that could provide a relatively rapid means of identifying haze-free targets (which may be more valuable targets for characterization) could potentially increase the science return for these telescopes. Our proposed method utilizes broadband observations of refracted light in the out-of-transit spectrum. Light refracted through an exoplanet atmosphere can lead to an increase of flux prior to ingress and subsequent to egress. Because this light is transmitted at pressures greater than those for typical cloud and haze layers, the detection of refracted light could indicate a cloud- or haze-free atmosphere. A detection of refracted light could be accomplished in <10 hr for Jovian exoplanets with JWST and <5 hr for super-Earths/mini-Neptunes with E-ELT. We find that this technique is most effective for planets with equilibrium temperatures between 200 and 500 K, which may include potentially habitable planets. A detection of refracted light for a potentially habitable planet would strongly suggest the planet was free of a global cloud or haze layer, and therefore a promising candidate for follow-up observations.

  10. Clearing the Cosmic Fog - The Most Distant Galaxy Ever Measured

    Science.gov (United States)

    2010-10-01

    A European team of astronomers using ESO's Very Large Telescope (VLT) has measured the distance to the most remote galaxy so far. By carefully analysing the very faint glow of the galaxy they have found that they are seeing it when the Universe was only about 600 million years old (a redshift of 8.6). These are the first confirmed observations of a galaxy whose light is clearing the opaque hydrogen fog that filled the cosmos at this early time. The results were presented at an online press conference with the scientists on 19 October 2010, and will appear in the 21 October issue of the journal Nature. "Using the ESO Very Large Telescope we have confirmed that a galaxy spotted earlier using Hubble is the most remote object identified so far in the Universe" [1], says Matt Lehnert (Observatoire de Paris) who is lead author of the paper reporting the results. "The power of the VLT and its SINFONI spectrograph allows us to actually measure the distance to this very faint galaxy and we find that we are seeing it when the Universe was less than 600 million years old." Studying these first galaxies is extremely difficult. By the time that their initially brilliant light gets to Earth they appear very faint and small. Furthermore, this dim light falls mostly in the infrared part of the spectrum because its wavelength has been stretched by the expansion of the Universe - an effect known as redshift. To make matters worse, at this early time, less than a billion years after the Big Bang, the Universe was not fully transparent and much of it was filled with a hydrogen fog that absorbed the fierce ultraviolet light from young galaxies. The period when the fog was still being cleared by this ultraviolet light is known as the era of reionisation [2]. Despite these challenges the new Wide Field Camera 3 on the NASA/ESA Hubble Space Telescope discovered several robust candidate objects in 2009 [3] that were thought to be galaxies shining in the era of reionisation. Confirming the

  11. 75 FR 8389 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2010-02-24

    ... Investment Justification. SUMMARY: The Federal Emergency Management Agency (FEMA) has submitted the... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Communications Grant Program (IECGP) AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice;...

  12. 78 FR 60300 - Agency Information Collection Activities: Submission for OMB Review; Comment Request; FEMA's...

    Science.gov (United States)

    2013-10-01

    ... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB Review; Comment Request; FEMA's Grants Reporting Tool (GRT) AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency (FEMA) will submit...

  13. 75 FR 38115 - Agency Information Collection Activities: Submission for OMB Review; Comment Request; FEMA Grants...

    Science.gov (United States)

    2010-07-01

    ... Federal Emergency Management Agency (FEMA) has submitted the information collection abstracted below to... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Emergency Management Agency, DHS. ACTION: Notice; 30-day notice and request for comments; revision of...

  14. 77 FR 21574 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, FEMA...

    Science.gov (United States)

    2012-04-10

    ... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB...: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency... addressed to the Desk Officer for the Department of Homeland Security, Federal Emergency Management...

  15. 75 FR 43995 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2010-07-27

    ...). SUMMARY: The Federal Emergency Management Agency (FEMA) will submit the information collection abstracted... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Sheet AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice; 30-day notice and request...

  16. 75 FR 38115 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2010-07-01

    ... Investment Justification Template. SUMMARY: The Federal Emergency Management Agency (FEMA) has submitted the... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... (SHSP) Tribal AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice; 30-day notice...

  17. 75 FR 8387 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2010-02-24

    ... Emergency Management Agency (FEMA) has submitted the information collection abstracted below to the Office... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Program (DLSGP) AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice; 30-day notice...

  18. 76 FR 37824 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2011-06-28

    ...), NFA Long-Term Evaluation Supervisors. SUMMARY: The Federal Emergency Management Agency (FEMA) will... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Department of Homeland Security, Federal Emergency Management Agency, and sent via electronic mail to...

  19. 75 FR 8385 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2010-02-24

    .... SUMMARY: The Federal Emergency Management Agency (FEMA) has submitted the information collection... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB...) AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice; 30-day notice and request for...

  20. 78 FR 60299 - Agency Information Collection Activities: Submission for OMB Review; Comment Request; FEMA...

    Science.gov (United States)

    2013-10-01

    ... Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency (FEMA) will submit... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Department of Homeland Security, Federal Emergency Management Agency, and sent via electronic mail to...

  1. 75 FR 6213 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2010-02-08

    ... Calculation Worksheet. SUMMARY: The Federal Emergency Management Agency (FEMA) has submitted the information... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Homeland Security, Federal Emergency Management Agency, and sent via electronic mail to...

  2. 75 FR 32199 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2010-06-07

    ... Federal Emergency Management Agency (FEMA) has submitted the information collection abstracted below to... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB... Emergency Management Agency, DHS. ACTION: Notice; 30-day notice and request for comments; extension,...

  3. 75 FR 66115 - Agency Information Collection Activities: Submission for OMB Review; Comment Request; FEMA...

    Science.gov (United States)

    2010-10-27

    ... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB Review; Comment Request; FEMA Mitigation Success Story Database AGENCY: Federal Emergency Management.... SUMMARY: The Federal Emergency Management Agency (FEMA) has submitted the information...

  4. 76 FR 13656 - Notice of Submission of Proposed Information Collection to OMB Requirement for Contractors to...

    Science.gov (United States)

    2011-03-14

    ... general liability, automobile liability insurance are in force before any construction work is started... forms of information technology, e.g., permitting electronic submission of responses. This notice also... certificates of insurance provide evidence that worker's compensation and general liability,...

  5. 76 FR 64368 - Notice of Submission of Proposed Information Collection to OMB Homelessness Prevention Study

    Science.gov (United States)

    2011-10-18

    ... URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB Homelessness Prevention... site visits that are part of HUD's Homelessness Prevention Study. The proposed information collection... collection for the Homelessness Prevention study that was already approved under emergency review...

  6. 76 FR 77020 - Agency Information Collection Activities; Submission for OMB Review; Comment Request; Coke Oven...

    Science.gov (United States)

    2011-12-09

    ... Information Collection Activities; Submission for OMB Review; Comment Request; Coke Oven Emissions ACTION... Administration (OSHA) sponsored information collection request (ICR) titled, ``Coke Oven Emissions,'' to the...: The purpose of Coke Oven Emissions Standard and its information collection requirements, codified...

  7. 77 FR 22797 - Submission of Proposed Information Collection to OMB: Certification of Consistency and Nexus...

    Science.gov (United States)

    2012-04-17

    ... URBAN DEVELOPMENT Submission of Proposed Information Collection to OMB: Certification of Consistency and Nexus Between Activities Proposed by the Applicant With Livability Principles Advanced in Preferred... applicant and the Livability Principles as they are being advanced in the Preferred Sustainability...

  8. 77 FR 37897 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

    Science.gov (United States)

    2012-06-25

    ... Right- To-Know Act (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice. SUMMARY: In... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Agency Information Collection Activities; Submission to OMB for Review and Approval;...

  9. 77 FR 36493 - Notice of Submission for OMB Review; Institute of Education Sciences; National Assessment of...

    Science.gov (United States)

    2012-06-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Institute of Education Sciences; National Assessment of Educational...) SUMMARY: The National Assessment of Educational Progress (NAEP) is a federally authorized survey...

  10. 78 FR 2997 - Agency Information Collection Activities; Submission for OMB Review; Comment Request: University...

    Science.gov (United States)

    2013-01-15

    ... HUMAN SERVICES Administration for Community Living Agency Information Collection Activities; Submission for OMB Review; Comment Request: University Centers for Excellence in Developmental Disabilities Education, Research, and Service--Annual Report AGENCY: Administration for Community Living, HHS....

  11. 78 FR 42983 - Submission for Renewal: Information Collection; Questionnaire for National Security Positions...

    Science.gov (United States)

    2013-07-18

    ... MANAGEMENT Submission for Renewal: Information Collection; Questionnaire for National Security Positions... request (ICR), Office of Management and Budget (OMB) Control No. 3206-0005, for Questionnaire for National... the revised information collection of information, Questionnaire for National Security Positions,...

  12. 75 FR 54287 - Submission of Electronic Documentation With Comailed and Copalletized Mailings

    Science.gov (United States)

    2010-09-07

    ... Register notice, Submission of Electronic Documentation with Comailed and Copalletized Mailings (75 FR... Part 111 Administrative practice and procedure, Postal Service. 0 Accordingly, 39 CFR Part 111 is... their origin, through the consolidation site, and ultimately into USPS processing. These...

  13. 76 FR 7577 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

    Science.gov (United States)

    2011-02-10

    ...-Information-Collections-Management@dhs.gov . SUPPLEMENTARY INFORMATION: Collection of Information Title: Debt... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No. 1660-0011; Debt Collection Financial Statement AGENCY: Federal...

  14. 76 FR 38201 - Notice of Submission of Proposed Information Collection to OMB; Fellowship Recruitment for the...

    Science.gov (United States)

    2011-06-29

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; Fellowship Recruitment... lists the following information: Title of Proposal: Fellowship Recruitment for the Fellowship...

  15. 75 FR 76260 - Conforming Changes to Applicant Submission Requirements; Implementing Federal Financial Report...

    Science.gov (United States)

    2010-12-08

    ... CFR Part 85 Accounting, Grant programs, Indians, Intergovernmental relations, Reporting and... reporting period end dates and due dates for the submission of cash management and financial information... connection with OMB's publications. With respect to financial reporting, this rule streamlines the...

  16. 40 CFR 86.079-36 - Submission of vehicle identification numbers.

    Science.gov (United States)

    2010-07-01

    ... and Heavy-Duty Engines, and for 1985 and Later Model Year New Gasoline Fueled, Natural Gas-Fueled, Liquefied Petroleum Gas-Fueled and Methanol-Fueled Heavy-Duty Vehicles § 86.079-36 Submission of...

  17. 76 FR 72424 - Submission for OMB Review; Comment Request Information Program on the Genetic Testing Registry

    Science.gov (United States)

    2011-11-23

    ... online submission system. Estimate of Burden: Although participation in the GTR is voluntary, in order to... information collection was previously published in the Federal Register on July 27, 2011, (76 FR 44937)...

  18. 76 FR 7874 - Notice of Proposed Information Collection for Public Comment on the Online Innovation Submission...

    Science.gov (United States)

    2011-02-11

    ... the public through the Innovation of the Day Project. ``Innovation of the Day'' is a new online submission and display platform located on HUD.gov , facilitated through the Office for International...

  19. 75 FR 45147 - Notice of Submission of Proposed Information Collection to OMB; Multifamily Project Construction...

    Science.gov (United States)

    2010-08-02

    ... lists the following information: Title of Proposal: Multifamily Project Construction Contract, Building... URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; Multifamily Project Construction Contract, Building Loan Agreement, & Construction Change; HUD Programs AGENCY: Office of the...

  20. 76 FR 65742 - Notice of Submission of Proposed Information Collection to OMB; Limited English Proficiency...

    Science.gov (United States)

    2011-10-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; Limited English... transmission of data. Title of Proposal: Limited English Proficiency Initiative Program Reporting. OMB...

  1. 76 FR 81958 - Notice of Submission of Proposed Information Collection to OMB; Limited English Proficiency...

    Science.gov (United States)

    2011-12-29

    ... URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB; Limited English... translated materials and other programs that support the assistance of persons with limited English... Following Information Title of Proposal: Limited English Proficiency Initiative (LEPI) Program. OMB...

  2. 78 FR 23825 - Information Collection Activities: Submission for the Office of Management and Budget (OMB...

    Science.gov (United States)

    2013-04-22

    ..., eligibility criteria, management information systems, program staffing, treatment, testing, courtroom... National Highway Traffic Safety Administration Information Collection Activities: Submission for the Office of Management and Budget (OMB) Review; Request for Comment AGENCY: National Highway Traffic...

  3. 75 FR 25864 - Submission for OMB Review; Comment Request; Lost People Finder System

    Science.gov (United States)

    2010-05-10

    ... (recovered) victims in a structured format, e.g., name (if available), age category and/or range, gender... Affairs, OIRA_submission@omb.eop.gov or by fax to 202-395-6974, Attention: Desk ] Officer for NIH....

  4. 77 FR 66863 - Notice of Submission of Proposed Information Collection to OMB Electronic Stakeholder Survey...

    Science.gov (United States)

    2012-11-07

    ... URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB Electronic Stakeholder... Stakeholder Survey is necessary to collect information for demonstrating the outputs and outcomes of meetings... lists the following information: Title of Proposed: Electronic Stakeholder Survey-Office...

  5. 76 FR 51046 - Agency Information Collection Activities: Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-08-17

    ... subdivisions of the State, and to nonprofit private entities (including community-based veterans' organizations... submission is for a collection of contextual, process, and outcome information to evaluate the national...

  6. 77 FR 6814 - Agency Information Collection Activities: Bonded Warehouse Proprietor's Submission

    Science.gov (United States)

    2012-02-09

    ... SECURITY U.S. Customs and Border Protection Agency Information Collection Activities: Bonded Warehouse... the Bonded Warehouse Proprietor's Submission (CBP Form 300). This request for comment is being made... CBP is soliciting comments concerning the following information collection: Title: Bonded...

  7. 78 FR 42091 - Agency Information Collection Activities: Submission for Office of Management and Budget (OMB...

    Science.gov (United States)

    2013-07-15

    ... HHS Mandatory Guidelines for Federal Workplace Drug Testing Programs (73 FR 71858) dated November 25..., incomplete submission of the information, refusal to provide a specimen, or substitution or adulteration of...

  8. 78 FR 55727 - Draft Guidance for Industry on Recommendations for Preparation and Submission of Animal Food...

    Science.gov (United States)

    2013-09-11

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Recommendations for Preparation and Submission of Animal Food Additive Petitions; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is announcing...

  9. 77 FR 21540 - Notice of Submission for OMB Review; Federal Student Aid; Comprehensive Transition Programs (CTP...

    Science.gov (United States)

    2012-04-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Federal Student Aid; Comprehensive Transition Programs (CTP) for... to this notice will be considered public records. Title of Collection: Comprehensive...

  10. 77 FR 8273 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, National...

    Science.gov (United States)

    2012-02-14

    ... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB Review; Comment Request, National Flood Insurance Program-Mortgage Portfolio Protection Program AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management...

  11. 77 FR 3482 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, National...

    Science.gov (United States)

    2012-01-24

    ... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB Review; Comment Request, National Flood Insurance Claims Appeals Process AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency (FEMA) has...

  12. 78 FR 33075 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

    Science.gov (United States)

    2013-06-03

    ... Agency Information Collection Activities; Submission to the Office of Management and Budget for Review... questionnaires. Wave 2 will contain technology and engineering literacy (TEL) and science ICT (interactive... Director, Information Collection Clearance Division, Privacy, Information and Records Management...

  13. 76 FR 39417 - Notice of Submission of Proposed Information Collection to OMB Tenant Resource Network Program

    Science.gov (United States)

    2011-07-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT Notice of Submission of Proposed Information Collection to OMB Tenant Resource Network... following information: Title of Proposal: Tenant Resource Network Program. OMB Approval Number:...

  14. 75 FR 20400 - Submission for Review: Federal Cyber Service: Scholarship for Service (SFS) Registration Web Site

    Science.gov (United States)

    2010-04-19

    ... MANAGEMENT Submission for Review: Federal Cyber Service: Scholarship for Service (SFS) Registration Web Site... Science Foundation in accordance with the Federal Cyber Service Training and Education Initiative as...- enrolled students in Federal agencies. Analysis Agency: Federal Cyber Service: Scholarship For...

  15. SDC Submission to the Environmental Audit Committee inquiry on : reducing carbon emissions from transport

    OpenAIRE

    Sustainable Development Commission

    2006-01-01

    In 2006 the Environmental Audit Committee launched an inquiry into how to reduce carbon emissions from transport. This is the Sustainable Development Commission's submission to the inquiry. Publisher PDF

  16. 76 FR 37353 - Federal Acquisition Regulation; Submission for OMB Review; Contractor Business Ethics Compliance...

    Science.gov (United States)

    2011-06-27

    ... Regulation; Submission for OMB Review; Contractor Business Ethics Compliance Program and Disclosure... requirement concerning contractor business ethics compliance program and disclosure requirements. Public... Information Collection 9000- 0164, Contractor Business Ethics Compliance Program and Disclosure...

  17. 76 FR 66311 - Draft Documents To Support Submission of an Electronic Common Technical Document; Availability

    Science.gov (United States)

    2011-10-26

    ..., Rockville, MD 20852-1448. Send one self- addressed adhesive label to assist that office in processing your... rules for submission processing and review, to refine the characterization of promotional marketing...

  18. On the Security of a Popular Web Submission and Review Software (WSaR) for Cryptology Conferences

    OpenAIRE

    Lo, Swee-Won; Phan, Raphael C.-W.; Goi, Bok-Min

    2007-01-01

    Most, if not all, conferences use an online system to handle paper submissions and reviews. Introduction of these systems has significantly facilitated the administration, submission and review process compared to traditional paper-based ones. However, it is crucial that these systems have strong resistance against Web attacks as they involve confidential data and privacy. Some submissions could be leading edge breakthroughs that authors do not wish to leak out and be subtly plagiarized. Al...

  19. Madeleine Leininger: claroscuro trascultural Madeleine Leininger: Clear and dark transcultural

    Directory of Open Access Journals (Sweden)

    David Fornons Fontdevila

    2010-09-01

    Full Text Available A principios de la década de los años 60, Madeleine Leininger conceptualiza y funda la Enfermería transcultural, pero a pesar de la vigencia y reconocimiento que actualmente posee la enfermería transcultural, ésta no se escapa de un territorio claro-oscuro de contradicciones y dicciones. ¿Qué concepto de cultura utiliza Madeleine Leininger? ¿Qué consecuencias implica su transculturalidad? En el artículo se debate la particularidad conceptual utilizada por Leininger. Así mismo se propone cambiar terminológicamente y conceptualmente significados y significantes como la etnoenfermería y los conceptos de transculturalidad que a ella refieren. Para evitar los determinismos culturales se considera más correcto hablar de las identidades culturales, propias e individuales. La enfermería debe establecer un diálogo transcultural con las identidades culturales, con las medicinas y enfermerías transculturales. Un diálogo en igualdad, no sin por ello renunciar a la riqueza y eficiencia de la enfermería y de la medicina occidentales.At the beginning of the decade of the 60s, Madeleine Leininger conceptualizes and founds the nursing transcultural, but in spite of the current force and recognition that nowadays possesses the nursing transcultural, this does not escape of a clear - dark territory of contradictions and dictions. What concept of culture does Madeleine Leininger use? What consequences does it imply her transculturality? In the article the conceptual particularity used by Leininger is debated. Likewise it proposes to change the term and conceptual important and significant as the etno-infirmary and the concepts of transcultural that recount her. To avoid the cultural determinisms it is more correct to speak about the cultural, own and individual identities. The nursing must establish a dialog transcultural with the cultural identities, with the medicines and transcultural nursing. A dialog in equality, not without for it to resign

  20. THE DEVELOPMENT OF AN ON-LINE SUBMISSION AND PEER REVIEW SYSTEM

    OpenAIRE

    P. Pavey; Probets, S.; Brailsford, D.

    2000-01-01

    Online submission and peer review is emerging as the next step forward for many journal publishers in an ever increasing drive to take advantage of technological improvements in transferring data electronically over the internet. The Electronic Submission and PEer REview (ESPERE) project was initiated in 1996 as an electronic Libraries (eLib) initiative of the Higher Education Funding Council for England (HEFCE). Subsequently the project continued as a self-funding group composed of a consort...

  1. The Relation Between Submissive Behaviours and Self Esteem State Among Nursing Students

    OpenAIRE

    Ilkay Arslan Ozkan; Ayse Ozen

    2008-01-01

    BACKGROUND: The aim of this study is to determine relationship between submissive acts and self esteem among nursing students. METHODS: This descriptive research has been performed with 322 nursing students in Akdeniz University, between February 2007-March 2007. Research data has derived by the questionnaire from that composed of two-parts. In the first part The Submissive Act Scale (SAS) and in the second part The Coopersmith Esteem Inventory (CSEI) has been used. The data analyzed by spea...

  2. NASA's Eos ClearingHOuse: Integrating Access to Data Services

    Science.gov (United States)

    Burnett, M. T.; Pfister, R.; Wichman, K.

    2002-12-01

    ECHO (The Earth Observing System (EOS) ClearingHOuse) is being developed to provide flexibility to NASA's EOS to better meet the needs of the science community. ECHO is a clearinghouse of metadata, representing the data offerings of participating data providers. ECHO is being built with the goal of being an enabling system: Enabling a variety of Data Providers to participate. Enabling access to an ever-changing variety of Earth Science Data. Enabling access to an ever-growing suite of services, provided by the Science Community, which improves the usefulness of this data, including the binding of those services to the data represented in the clearinghouse. The purpose of this enabling philosophy is to support current Science efforts, but also to give the opportunity for creative organizations and individuals to break the traditional paradigm for discovering and leveraging Earth Science Data and Services in completely new ways. This presentation will focus on ECHO's approach to integrating Data Services from varied Service Providers, and facilitating access to those services by the user community. ECHO can be viewed as a typical Service oriented architecture. The fundamental interactions that it supports are (abstractly) Publish, Find and Bind. ECHO provides interfaces and mechanisms that allow organizations to publish their services. Using these interfaces, Service Providers can effectively "plug-in" their capabilities. There are mechanisms that allow the correlation of their service to the data types in the clearinghouse. ECHO's user community can find, or discover, services through a separate set of interfaces. Bindings are the mechanisms that support the invocation of services by ECHO's user community. ECHO supports binding either directly between the user and the service provider, or indirectly by using ECHO as a Service Broker. ECHO is supporting all of these Service capabilities by leveraging the contemporary (and evolving) "standards" of Web Services. Web

  3. Stony Brook's Graduate Courses in Clear, Vivid, Conversational Communication

    Science.gov (United States)

    Bass, E.

    2011-12-01

    Graduate students in the sciences at Stony Brook University are taking for-credit courses to learn to communicate more effectively about science with people outside their disciplines, including public officials, the press, students, potential funders and employers, colleagues in other fields, and the general public. Five Communicating Science courses are offered; two more will be added in January, 2012. The courses are offered by the School of Journalism and developed by the Center for Communicating Science (CCS). This interdisciplinary center was founded in 2009, with the participation of Alan Alda, the actor, writer, director and longtime advocate for science, who is a Visiting Professor at Stony Brook. At the core of the program are three 1-credit (14-hour) modules that rely on experiential learning, repeated practice and immediate, interactive feedback. In Distilling Your Message, students practice speaking clearly, vividly and conversationally about their work at different levels of complexity and formality to different audiences, using storytelling techniques where appropriate. In Writing for the Public, they extend these skills into writing. In Improvisation for Scientists, the most unconventional of the courses, students play improvisational theater games to help themselves connect more directly, personally and responsively with their audiences. In their first two semesters, the courses are expected to serve about 90 students, taking a total of about 180 credits. Most of the courses have filled quickly, mixing master's and doctoral students from more than a dozen fields, including marine and atmospheric sciences. Three to six credits of Communicating Science courses are required for students in two programs, an MA in Marine Conservation and Policy and an Advanced Certificate in Health Communications. The content and methods of the courses are based largely on lessons learned from evaluations of all-day workshops that CCS has conducted for more than 250

  4. Clear cell papillary renal cell carcinoma and clear cell renal cell carcinoma arising in acquired cystic disease of the kidney: an immunohistochemical and genetic study.

    Science.gov (United States)

    Kuroda, Naoto; Shiotsu, Tomoyuki; Kawada, Chiaki; Shuin, Taro; Hes, Ondrej; Michal, Michal; Ohe, Chisato; Mikami, Shuji; Pan, Chin-Chen

    2011-08-01

    Clear cell papillary renal cell carcinoma (RCC) is a recently established disease entity. However, there are few reports on genetic study of this entity. We report such a case with focus on genetic study. A 57-year-old Japanese man was found to have 3 renal tumors. Histologically, two tumors showed findings of clear cell RCC; and the other tumor showed findings of clear cell papillary RCC that was characterized by papillary growth pattern of neoplastic cells in cystic space with purely clear cell cytology. Immunohistochemically, tumor cells of clear cell papillary RCC were diffusely positive for PAX2 and cytokeratin 7, but negative for CD10, RCC Ma, and AMACR. In fluorescence in situ hybridization study for one clear cell papillary RCC, we detected polysomy for chromosome 7 and monosomy for chromosomes 17, 16, and 20. In addition, we detected mutation of VHL gene in clear cell RCC, but found no VHL gene mutation in clear cell papillary RCC. Finally, our results provide further evidence that clear cell papillary RCC may be both morphologically and genetically distinct entity from clear cell RCC and papillary RCC. PMID:20952286

  5. Evaluation of Clear Sky Models for Satellite-Based Irradiance Estimates

    Energy Technology Data Exchange (ETDEWEB)

    Sengupta, M.; Gotseff, P.

    2013-12-01

    This report describes an intercomparison of three popular broadband clear sky solar irradiance model results with measured data, as well as satellite-based model clear sky results compared to measured clear sky data. The authors conclude that one of the popular clear sky models (the Bird clear sky model developed by Richard Bird and Roland Hulstrom) could serve as a more accurate replacement for current satellite-model clear sky estimations. Additionally, the analysis of the model results with respect to model input parameters indicates that rather than climatological, annual, or monthly mean input data, higher-time-resolution input parameters improve the general clear sky model performance.

  6. CLEAR Landscape Change Module: No Increased Restoration and Protection, UTM Zone 15N NAD83, Coastal Louisiana Ecosystem Assessment and Restoration (2007), [CLEAR_Output_NIA_012307_final

    Data.gov (United States)

    Louisiana Geographic Information Center — The Coastal Louisiana Ecosystem Assessment and Restoration (CLEAR) Framework is an integrated ecosystem forecasting system, designed to simulate ecological change...

  7. Submission to the Federal Government green plan consultation process

    International Nuclear Information System (INIS)

    The Canadian Nuclear Association is a voluntary membership organization which represents the nuclear industry in discussions with government and the public on matters of interest and concern to the industry. A specific area in which the use of nuclear power makes a significant contribution to addressing the major environmental concern of global warming is in replacing the use of fossil fuels to generate electricity. The 1988 World Conference on the Changing Atmosphere suggested with qualifications, that 'nuclear power could have a role to play in lowering carbon dioxide emissions'. This submission examines the potential of nuclear power to play a role in lowering carbon dioxide emissions both in the short term, up to the year 2005 and beyond. 1 fig

  8. Physics and medicine: ICTR-PHE 2016 opens abstract submission

    CERN Multimedia

    2015-01-01

    The third edition of the joint ICTR (International Conference on Transnational Research in Radiation Oncology) and PHE (Physics for Health in Europe) conference (see here) will take place from 15 to 19 February 2016 at the Geneva International Conference Centre (CICG). This biennial event, co-organised by CERN, has become a staple amongst the scientific communities involved in multidisciplinary research at the crossing of physics, medicine, and biology.   Abstract submission and registration are now open: detector physicists, radiochemists, nuclear-medicine physicians and physicists, biologists, software developers, accelerator experts, and oncologists are encouraged to “think outside the box” and make innovative proposals. Last year’s programme shows the breadth and diversity of subjects, which makes this conference a unique place to showcase your research, see how the same topic is approached by different disciplines, engage in stimulating discussions,...

  9. Physics and medicine: ICTR-PHE 2016 opens abstract submission

    CERN Multimedia

    2015-01-01

    The third edition of the joint ICTR (International Conference on Transnational Research in Radiation Oncology) and PHE (Physics for Health in Europe) conference (see here) will take place from 15 to 19 February 2016 at the Geneva International Conference Centre (CICG). This biennial event, co-organised by CERN, has become a staple amongst the scientific communities involved in multidisciplinary research at the crossing of physics, medicine, and biology.   Abstract submission and registration are now open: detector physicists, radiochemists, nuclear-medicine physicians and physicists, biologists, software developers, accelerator experts, and oncologists are encouraged to “think outside the box” and make innovative proposals. Last year’s programme shows the breadth and diversity of subjects, which makes this conference a unique place to showcase your research, see how the same topic is approached by different disciplines, engage in stimulating discussions, ...

  10. 7 CFR 205.621 - Submission and determination of proposed State organic programs and amendments to approved State...

    Science.gov (United States)

    2010-01-01

    ...) Submission of a request for amendment of an approved State organic program must contain supporting materials... official may submit a revised State organic program or amendment of such a program at any time. ... 7 Agriculture 3 2010-01-01 2010-01-01 false Submission and determination of proposed State...

  11. 28 CFR 81.2 - Submission of reports; designation of agencies to receive reports of child abuse.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Submission of reports; designation of agencies to receive reports of child abuse. 81.2 Section 81.2 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CHILD ABUSE AND CHILD PORNOGRAPHY REPORTING DESIGNATIONS AND PROCEDURES § 81.2 Submission...

  12. 17 CFR 240.17a-25 - Electronic submission of securities transaction information by exchange members, brokers, and...

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Electronic submission of... Preservation of Records and Reports of Certain Stabilizing Activities § 240.17a-25 Electronic submission of... transaction was a purchase, sale, or short sale; and, if an options contract, whether open long or short...

  13. Enlargement of the European Union: Forfás Submission to National Forum on Europe, January 2002

    OpenAIRE

    2002-01-01

    This submission from Forfás has been prepared in response to a request from the National Forum on Europe for submissions on Ireland's experience of and evolving relationship with the European Union, with particular reference to the implications of enlargement of the Union for Ireland.

  14. Pediatric evaluation of the ClearVoice™ speech enhancement algorithm in everyday life

    Directory of Open Access Journals (Sweden)

    Nathalie Noël-Petroff

    2013-12-01

    Full Text Available ClearVoice™ enables Advanced Bionics cochlear implant users to improve their speech understanding in difficult listening environments, without compromising performance in quiet situations. The aim of the study was to evaluate the benefits of ClearVoice in children. Children between six and fourteen years of age randomly tested two modalities of ClearVoice for one month each. The baseline program, HiRes 120™, and both ClearVoice programs were evaluated with a sentence test in quiet and noise. Parents and teachers completed a questionnaire related to everyday noisy situations. The switchover to ClearVoice was uneventful for both modalities. Adjustments to thresholds and comfort levels were required. Seven out of the nine children preferred a ClearVoice program. No impact of ClearVoice on performance in quiet was observed and both modalities of ClearVoice improved speech understanding in noise compared to the baseline program, significantly with ClearVoice high. Positive outcomes were obtained from the questionnaires and discussions with parents and children. This study showed that children benefited from using ClearVoice in their daily life. There was a clear trend towards improved speech understanding in noise with ClearVoice, without affecting performance in quiet; therefore ClearVoice can be used by children all day, without having to change programs.

  15. 21 CFR 878.9 - Limitations of exemptions from section 510(k) of the Federal Food, Drug, and Cosmetic Act (the act).

    Science.gov (United States)

    2010-04-01

    ... the Federal Food, Drug, and Cosmetic Act (the act). 878.9 Section 878.9 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL AND PLASTIC SURGERY..., and Cosmetic Act (the act). The exemption from the requirement of premarket notification (section...

  16. 21 CFR 864.9 - Limitations of exemptions from section 510(k) of the Federal Food, Drug, and Cosmetic Act (the act).

    Science.gov (United States)

    2010-04-01

    ... ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES HEMATOLOGY AND PATHOLOGY...) For assessing the risk of cardiovascular diseases; (5) For use in diabetes management; (6)...

  17. 75 FR 68014 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing and Immediate...

    Science.gov (United States)

    2010-11-04

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing and Immediate... the Fixed Income Clearing Corporation (``FICC'') filed with the Securities and Exchange...

  18. 78 FR 52598 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Proposed...

    Science.gov (United States)

    2013-08-23

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Proposed..., the Fixed Income Clearing Corporation (``FICC'') filed with the Securities and Exchange...

  19. 77 FR 15822 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Proposed...

    Science.gov (United States)

    2012-03-16

    ... COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Proposed... Fixed Income Clearing Corporation (``FICC'') filed with the Securities and Exchange Commission... modifications to certain rules of the Government Securities Division (``GSD'') of the Fixed Income...

  20. 76 FR 13683 - Self-Regulatory Organizations; The Fixed Income Clearing Corporation; Notice of Filing and...

    Science.gov (United States)

    2011-03-14

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; The Fixed Income Clearing Corporation; Notice of Filing and... 2, 2011, the Fixed Income Clearing Corporation (``FICC'') filed with the Securities and...

  1. 78 FR 33456 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing Proposed Rule...

    Science.gov (United States)

    2013-06-04

    ... From the Federal Register Online via the Government Publishing Office SECURITIES AND EXCHANGE COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing Proposed Rule... Fixed Income Clearing Corporation (``FICC'') filed with the Securities and Exchange...

  2. The Relation Between Submissive Behaviours and Self Esteem State Among Nursing Students

    Directory of Open Access Journals (Sweden)

    Ilkay Arslan Ozkan

    2008-02-01

    Full Text Available BACKGROUND: The aim of this study is to determine relationship between submissive acts and self esteem among nursing students. METHODS: This descriptive research has been performed with 322 nursing students in Akdeniz University, between February 2007-March 2007. Research data has derived by the questionnaire from that composed of two-parts. In the first part The Submissive Act Scale (SAS and in the second part The Coopersmith Esteem Inventory (CSEI has been used. The data analyzed by spearman’s correlation analysis. RESULTS: According to collected data; the students, who has participated to research 34.88 +-8.7 SAS average and 74.78 +/- 16.2 CSEI average has been established. 47 % of the students have SAS points more than average and 65 % of the students have high self esteem level is confirmed. As a result correlation analysis, significant relationship has determined between submissive acts and self esteem (r=- 0.42, p<0.01. According to the findings; submissive acts were negatively correlated with self esteem. CONCLUSION: Communications and interpersonal relationships are very important for nursing. Nurses play a vital communication role in the healthcare system. Assertiveness and self esteem is necessary for effective nurse communication. Because of the process of becoming a nurse is started at nursing school, nursing education should be more promote to self esteem and decreased to submissive behaviours through educational methods. [TAF Prev Med Bull 2008; 7(1.000: 53-58

  3. The Relation Between Submissive Behaviours and Self Esteem State Among Nursing Students

    Directory of Open Access Journals (Sweden)

    Ilkay Arslan Ozkan

    2008-02-01

    Full Text Available BACKGROUND: The aim of this study is to determine relationship between submissive acts and self esteem among nursing students. METHODS: This descriptive research has been performed with 322 nursing students in Akdeniz University, between February 2007-March 2007. Research data has derived by the questionnaire from that composed of two-parts. In the first part The Submissive Act Scale (SAS and in the second part The Coopersmith Esteem Inventory (CSEI has been used. The data analyzed by spearman’s correlation analysis. RESULTS: According to collected data; the students, who has participated to research 34.88 +-8.7 SAS average and 74.78 +/- 16.2 CSEI average has been established. 47 % of the students have SAS points more than average and 65 % of the students have high self esteem level is confirmed. As a result correlation analysis, significant relationship has determined between submissive acts and self esteem (r=- 0.42, p<0.01. According to the findings; submissive acts were negatively correlated with self esteem. CONCLUSION: Communications and interpersonal relationships are very important for nursing. Nurses play a vital communication role in the healthcare system. Assertiveness and self esteem is necessary for effective nurse communication. Because of the process of becoming a nurse is started at nursing school, nursing education should be more promote to self esteem and decreased to submissive behaviours through educational methods. [TAF Prev Med Bull. 2008; 7(1: 53-58

  4. Light-sheet microscopy imaging of a whole cleared rat brain with Thy1-GFP transgene

    OpenAIRE

    Marzena Stefaniuk; Gualda, Emilio J.; Monika Pawlowska; Diana Legutko; Paweł Matryba; Paulina Koza; Witold Konopka; Dorota Owczarek; Marcin Wawrzyniak; Pablo Loza-Alvarez; Leszek Kaczmarek

    2016-01-01

    Whole-brain imaging with light-sheet fluorescence microscopy and optically cleared tissue is a new, rapidly developing research field. Whereas successful attempts to clear and image mouse brain have been reported, a similar result for rats has proven difficult to achieve. Herein, we report on creating novel transgenic rat harboring fluorescent reporter GFP under control of neuronal gene promoter. We then present data on clearing the rat brain, showing that FluoClearBABB was found superior ove...

  5. Perception of foreign-accented clear speech by younger and older English listeners

    OpenAIRE

    Li, Chi-Nin

    2009-01-01

    Naturally produced English clear speech has been shown to be more intelligible than English conversational speech. However, little is known about the extent of the clear speech effects in the production of nonnative English, and perception of foreign-accented English by younger and older listeners. The present study examined whether Cantonese speakers would employ the same strategies as those used by native English speakers in producing clear speech in their second language. Also, the clear s...

  6. An acoustic-phonetic comparison of the clear speaking styles of late Finnish-English bilinguals

    OpenAIRE

    Granlund, S.; Hazan, V.; Baker, R.

    2012-01-01

    Research on clear speech, an intelligibility-enhancing speaking style, has proposed that global clear speech modifications which make speech more perceptible in adverse conditions are language-independent, while the more fine-grained segmental clear speech modifications, which enhance the salience of phonological contrasts, are language-specific [Bradlow, A.R. & Bent, T., 2002. The clear speech effect for non-native listeners. Journal of the Acoustical Society of America, 112, 272–284]. This ...

  7. Total Value Assessment of Tree Clearing for Developing Grazing Systems in Central Queensland

    OpenAIRE

    Kaur, Kamaljit; Stanley, Owen

    2006-01-01

    Tree clearing is widely practised in Queensland to develop exotic pastures to enhance pasture production and hence the financial gains. One of the major woodland community i.e. brigalow (Acacia harpop hylla) was targeted for clearing in the early 1950s due to its fertile soils. Recently, some marginal communities such as Poplar box (Eucalyptus populnea) and Iron bark (Eucalyptus melanophloia) are targeted for clearing. Net benefits from clearing woodlands to increase pasture production, hence...

  8. What the EWSR1-ATF1 Fusion has Taught Us About Hyalinizing Clear Cell Carcinoma

    OpenAIRE

    Tanguay, Jeff; Weinreb, Ilan

    2013-01-01

    Hyalinizing clear cell carcinoma (HCCC) is a unique low-grade tumor composed of cords and nests of clear cells in a hyalinized stroma that was first reported by Milchgrub et al. It was recognized as a separate entity from clear cell variants of epithelial-myoepithelial carcinoma, myoepithelial carcinoma and mucoepidermoid carcinoma. HCCC is included in a long list of clear cell-containing tumors of salivary gland, as well as odontogenic tumors and metastases (renal cell carcinoma). Up until n...

  9. Clear cell variant of intraosseous mucoepidermoid carcinoma: Report of a rare entity

    Directory of Open Access Journals (Sweden)

    Sujatha Varma

    2012-01-01

    Full Text Available Intraosseous mucoepidermoid carcinoma of jaw bones is a rare lesion. Abundance of clear cells in an intraosseous mucoepidermoid carcinoma may complicate its histopathologic diagnosis. It becomes extremely important to distinguish this lesion from other clear cell lesions of jaw region. Here, we report a case of clear cell variant of intraosseous mucoepidermoid carcinoma in the mandible.

  10. 77 FR 63398 - Self-Regulatory Organizations; The Options Clearing Corporation; Notice of Filing and Immediate...

    Science.gov (United States)

    2012-10-16

    ... of the Securities Exchange Act of 1934, as amended (the ``Act''), because it reduces the clearing fee... COMMISSION Self-Regulatory Organizations; The Options Clearing Corporation; Notice of Filing and Immediate Effectiveness of Proposed Rule Change To Reduce the Per Contract Clearing Fee for Routing Trades Executed...

  11. Clear cell variant of intraosseous mucoepidermoid carcinoma: Report of a rare entity

    OpenAIRE

    Sujatha Varma; P. M. Shameena; Sudha, S; Resmi G Nair; Ipe V Varghese

    2012-01-01

    Intraosseous mucoepidermoid carcinoma of jaw bones is a rare lesion. Abundance of clear cells in an intraosseous mucoepidermoid carcinoma may complicate its histopathologic diagnosis. It becomes extremely important to distinguish this lesion from other clear cell lesions of jaw region. Here, we report a case of clear cell variant of intraosseous mucoepidermoid carcinoma in the mandible.

  12. 76 FR 31518 - Public Roundtable on the Protection of Cleared Swaps Customer Collateral

    Science.gov (United States)

    2011-06-01

    ... COMMISSION 17 CFR Parts 22 and 190 Public Roundtable on the Protection of Cleared Swaps Customer Collateral... related to the protection of cleared swaps customer collateral described in the CFTC's notice of proposed rulemaking regarding the Protection of Cleared Swaps Customer Contracts and Collateral and...

  13. 77 FR 32153 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Proposed...

    Science.gov (United States)

    2012-05-31

    ... COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing of Proposed... hereby given that on May 15, 2012, Fixed Income Clearing Corporation (``FICC'') filed with the Securities... Clearing Fund formula is driven by historical data observed in the fixed-income market. While the...

  14. 78 FR 39027 - Order Granting the Fixed Income Clearing Corporation's Amended Application for Permanent...

    Science.gov (United States)

    2013-06-28

    ... COMMISSION Order Granting the Fixed Income Clearing Corporation's Amended Application for Permanent Registration as a Clearing Agency June 24, 2013. I. Introduction On April 5, 2013, the Fixed Income Clearing... Securities Exchange Act Release No. 69362 (April 11, 2013), 78 FR 22923-01 (April 17, 2013) (File No....

  15. 77 FR 40398 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule...

    Science.gov (United States)

    2012-07-09

    ... COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Approving Proposed Rule..., 2012, the Fixed Income Clearing Corporation (``FICC'') filed with the Securities and Exchange... Clearing Fund formula is driven by historical data observed in the fixed-income market. While the...

  16. 75 FR 4430 - Self-Regulatory Organizations; The Fixed Income Clearing Corporation; Notice of Filing and...

    Science.gov (United States)

    2010-01-27

    ... COMMISSION Self-Regulatory Organizations; The Fixed Income Clearing Corporation; Notice of Filing and... Division of the Fixed Income Clearing Corporation January 21, 2010. Pursuant to Section 19(b)(1) of the... Income Clearing Corporation (``FICC'') filed with the Securities and Exchange Commission...

  17. 76 FR 12144 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Granting Approval of a...

    Science.gov (United States)

    2011-03-04

    ... COMMISSION Self-Regulatory Organizations; Fixed Income Clearing Corporation; Order Granting Approval of a Proposed Rule Change To Introduce Cross- Margining of Certain Positions Cleared at the Fixed Income.... Introduction On November 12, 2010, Fixed Income Clearing Corporation (``FICC'') filed with the Securities...

  18. Clear & Simple

    Science.gov (United States)

    ... thrill seeking behavior, views toward or participation in violence) Related knowledge, attitudes, and practices (e.g., stigma, shame, discrimination) Patterns of use of related services (urban vs. rural, access to services, travel distance and ...

  19. Optical clearing assisted confocal microscopy of ex vivo transgenic mouse skin

    Science.gov (United States)

    Song, Eunjoo; Ahn, YoonJoon; Ahn, Jinhyo; Ahn, Soyeon; Kim, Changhwan; Choi, Sanghoon; Boutilier, Richard Martin; Lee, Yongjoong; Kim, Pilhan; Lee, Ho

    2015-10-01

    We examined the optical clearing assisted confocal microscopy of the transgenic mouse skin. The pinna and dorsal skin were imaged with a confocal microscope after the application of glycerol and FocusClear. In case of the glycerol-treated pinna, the clearing was minimal due to the inefficient permeability. However, the imaging depth was improved when the pinna was treated with FocusClear. In case of dorsal skin, we were able to image deeply to the subcutaneous connective tissue with both agents. Various skin structures such as the vessel, epithelium cells, cartilage, dermal cells, and hair follicles were clearly imaged.

  20. The Research on Submissive Behaviour of Students in the Second Level of Elementary School

    Directory of Open Access Journals (Sweden)

    Abdullah ATLİ

    2010-04-01

    Full Text Available This study examined the submissive behaviors of second level of elementary school students at with respect to some variables. Participants were 430 students, 172 (42,6 % girls and 231 (57,4 % boys. Among these participants, 156 (38,6 % were 6th graders, 104 (26% were 7th graders, and 143 (35,4% were 8th graders. The data were collected using Student Personal Information Form developed by researchers and Submissive Behaviors Scale. The data collected were analyzed using t-test, One-way ANOVA, Tukey Test, and Mann–Whitney U test. The findings revealed that students’ levels of submissive behaviors significantly differed by the variables including school type, gender, school class level, achievement, residence, economic level, mother’s and father’s education level, violence by mother and father.