WorldWideScience

Sample records for clearances navigation

  1. 33 CFR 160.115 - Withholding of clearance.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Withholding of clearance. 160.115 Section 160.115 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY PORTS AND WATERWAYS SAFETY-GENERAL Control of Vessel and Facility Operations § 160.115 Withholding of clearance....

  2. Mucociliary clearance

    DEFF Research Database (Denmark)

    Munkholm, Mathias; Mortensen, Jann

    2014-01-01

    Mucociliary clearance has long been known to be a significant innate defence mechanism against inhaled microbes and irritants. Important knowledge has been gathered regarding the anatomy and physiology of this system, and in recent years, extensive studies of the pathophysiology related to lung...... diseases characterized by defective mucus clearance have resulted in a variety of therapies, which might be able to enhance clearance from the lungs. In addition, ways to study in vivo mucociliary clearance in humans have been developed. This can be used as a means to assess the effect of different...... pharmacological interventions on clearance rate, to study the importance of defective mucus clearance in different lung diseases or as a diagnostic tool in the work-up of patients with recurrent airway diseases. The aim of this review is to provide an overview of the anatomy, physiology, pathophysiology, and...

  3. 33 CFR 157.455 - Minimum under-keel clearance.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Minimum under-keel clearance. 157.455 Section 157.455 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Interim Measures for Certain...

  4. 33 CFR 151.1508 - Revocation of clearance.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Revocation of clearance. 151.1508 Section 151.1508 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION VESSELS CARRYING OIL, NOXIOUS LIQUID SUBSTANCES, GARBAGE, MUNICIPAL OR COMMERCIAL WASTE, AND BALLAST WATER Ballast Water...

  5. 14 CFR 375.24 - Entry and clearance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Entry and clearance. 375.24 Section 375.24 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS NAVIGATION OF FOREIGN CIVIL AIRCRAFT WITHIN THE UNITED STATES Rules Generally Applicable § 375.24 Entry and clearance. All...

  6. Navigation systems

    OpenAIRE

    Ocepek, Marjan

    2013-01-01

    In this thesis we present different navigation systems which may be used also in surveying. Map as a basis of navigation is described at the beginning. Next, we focus on navigation based on celestial bodies. We present basic terms such as navigation and orientation and describe some primitive methods, which had been used for orientation without compass. We present two important time keeping instruments that facilitated the process of position determination, the chronometer and chronograph, an...

  7. Renal clearance of melatonin

    OpenAIRE

    Editorial Office

    1996-01-01

    Only two publications exist in which actual values for the renal clearance of intact melatonin in man is described. The melatonin clearance values were, however, obtained either after the oral intake of melatonin, or by applying different techniques for the determination of melatonin in urine and plasma. In this study, renal clearance of melatonin was determined during the hours where melatonin concentrations are relatively constant. Melatonin levels in plasma and urine respectively were e...

  8. The parasite clearance curve

    OpenAIRE

    White NJ

    2011-01-01

    Abstract Parasite clearance rates are important measures of anti-malarial drug efficacy. They are particularly important in the assessment of artemisinin resistance. The slope of the log-linear segment in the middle of the parasite clearance curve has the least inter-individual variance and is the focus of therapeutic assessment. The factors affecting parasite clearance are reviewed. Methods of presentation and the approaches to analysis are discussed.

  9. Security Clearance Tracking System

    Data.gov (United States)

    National Archives and Records Administration — SCTS supports the adjudication process of private background investigations and clearances for potential employees, contractors, interns and student workers.

  10. Calculating Clearances for Manipulators

    Science.gov (United States)

    Copeland, E. L.; Peticolas, J. D.; Ray, L. D.

    1983-01-01

    Set of algorithms rapidly calculates minimum safe clearances for remote manipulators. Such calculations are used in design of trajectories for manipulators to ensure they do not accidentally strike surrounding objects. Structural parts are considered as cylindrical shells having circular plane areas for ends. Clearance calculation method offers special benefits in industrial robotics, particularly in automated machining.

  11. NAVIGATOR (FER)

    International Nuclear Information System (INIS)

    The NAVIGATOR concept is based on the negative-ion-grounded 500 keV/20 MW neutral beam injection system (NBI system), which has been proposed and studied at JAERI. The NAVIGATOR concept contains two categories; one is the NAVIGATOR machine as a tokamak reactor, and the other is the NAVIGATOR philosphy as a quiding principle in fusion research. The NAVIGATOR concept should be applied in a phased approach to and beyond the operating goal for the FER (Fusion Experimental Reactor, the next generation tokamak machine in Japan). The mission of the FER is to realize self-ignition and a long controlled burn of about 800 seconds and to develop and test fusion technologies, including the tritiumfuel cycle, superconducting magnet, remote maintenance and breeding blanket test modules. The NAVIGATOR concept is composed of three major elements, that is, reliable operation scenarios, reliable maintenability and suffiecient flexibility of the reactor. The NAVIGATOR concept well supports the ideas of phased operation and phased construction of the FER, which will result in the reduction technological risk. (author). 4 refs.; 3 figs

  12. Ecodesign Navigator

    DEFF Research Database (Denmark)

    Simon, M; Evans, S.; McAloone, Timothy Charles; Sweatman, A.; Bhamra, T.; Poole, S.

    The Ecodesign Navigator is the product of a three-year research project called DEEDS - DEsign for Environment Decision Support. The initial partners were Manchester Metropolitan University, Cranfield University, Engineering 6 Physical Sciences Resaech Council, Electrolux, ICL, and the Industry...

  13. Renal Clearance of Nanoparticles

    OpenAIRE

    Choi, Hak Soo; Liu, Wenhao; Misra, Preeti; Tanaka, Eiichi; Zimmer, John P.; Ipe, Binil Itty; Bawendi, Moungi G.; Frangioni, John V.

    2007-01-01

    The field of nanotechnology holds great promise for the diagnosis and treatment of human disease. However, the size and charge of most nanoparticles preclude their efficient clearance from the body as intact nanoparticles. Without such clearance or their biodegradation into biologically benign components, toxicity is potentially amplified and radiological imaging is hindered. Using quantum dots (QDs) as a model system, we have precisely defined the requirements for renal filtration and urinar...

  14. Optimisation-based clearance

    OpenAIRE

    Varga, Andras

    2002-01-01

    The basic feature of the optimisation-based clearance approach is to reformulate the clearance problems as equivalent minimum distance problems for which ”anti”-optimisation is performed to determine the worst-case parameter combination/ flight condition leading to worst performance. The basic requirements for the applicability of the optimisation-based approach are the availability of suitable parametric models describing the overall nonlinear dynamics of the augmented aircraft and of accomp...

  15. Generic Clearance Values

    International Nuclear Information System (INIS)

    This paper analyzes the Generic Clearance Values established for natural and artificial radionuclides with the objective of evaluating their degree of conservatism in views of adopting them into the regulatory body. Generic clearance values for natural radionuclides have been chosen by experts judgments as the optimum boundary between, on the one hand, the ubiquitous unmodified soil concentrations and, on the other hand, activity concentrations in ores, mineral sands, industrial residues and wastes. For artificial radionuclides the clearance levels have been derived from the scenarios postulated in the document Safety Reports Series 44 of the IAEA considering quantitative exemption criteria. A set of 8 scenarios were postulated covering external, ingestion and inhalation exposure pathways. For each radionuclide, the generic clearance level was derived as the more restrictive value obtained from the scenarios, that is the lowest ratio between the applicable individual dose and the dose per unit activity concentration (Bq/g). The individual dose was calculated by a formula depending on each scenario and pathway, with different parameters, such as exposure time, dosimetric factors, dilution factor, density of the material, geometric factors, etc. It was concluded that the basis and parameters used for the derivation of the generic clearance levels are quite conservative and therefore its the adoption in Argentina has been recommended. It is expected that their implementation will contribute to optimize the regulatory management system. (authors)

  16. Generic clearance values

    International Nuclear Information System (INIS)

    This paper analyzes the Generic Clearance Values established for natural and artificial radionuclides with the objective of evaluating their degree of conservatism in views of adopting them into the regulatory body. Generic clearance values for natural radionuclides have been chosen by experts judgments as the optimum boundary between, on one hand, the ubiquitous unmodified soil concentrations and, on the other hand, activity concentrations in ores, mineral sands, industrial residues and wastes. For artificial radionuclides the clearance levels have been derived from the scenarios postulated in the document 'Safety Reports Series Nr 44' of the IAEA considering quantitative exemption criteria. A set of 8 scenarios were postulated covering external, ingestion and inhalation exposure pathways. For each radionuclide, the generic clearance level was derived as the more restrictive value obtained from the scenarios, that is the lowest ratio between the applicable individual dose and the dose per unit activity concentration (Bq/g). The individual dose was calculated by a formula depending on each scenario and pathway, with different parameters, such as exposure time, dosimetric factors, dilution factor, density of the material, geometric factors, etc. It was concluded that the basis and parameters used for the derivation of the generic clearance levels are quite conservative and therefore its the adoption in Argentina has been recommended. It is expected that their implementation will contribute to optimize the regulatory management system. (author)

  17. Study on clearance system

    International Nuclear Information System (INIS)

    The clearance system is a legal system to release 'the radioactive waste not requiring treatment as radioactive waste' from the regulatory control. JNES supports NISA on approval and confirmation of clearance measurement and judgment developed by the operator. The objective of this study is to establish technical base of the validation method of the clearance measurement for various objects. In reactor facilities, the bulk measurement technique or the statistical sampling measurement technique may be applied to large scale objects or concrete walls. In this study, the criteria of those techniques were examined. In uranium processing facilities, it is important to confirm surface state of the object in case of detecting alpha rays. The result of the examination about the influence of the surface rust in the uranium clearance measurement by the alpha ray measurement showed that the pollution was distributed in rust layer uniformly. This result will be reflected to the revision of the Ministerial Ordinance on Clearance in 2011FY. To develop a manual for unexpected incidents, the response procedure for an unexpected incident was prepared, including a response system. (author)

  18. Study on clearance system

    International Nuclear Information System (INIS)

    The clearance system is a legal word to define as 'the waste not requiring treatment as radioactive waste' on the regulatory control. JNES supports NISA on the approval and the confirmation of clearance measurement by the operator. The objective of this study is to establish technical base of the validation method of the clearance measurement for various objects. In reactor facilities, the statistical sampling measurement technique may be applied to large scale objects. In this study, the criteria of the techniques were examined, and the strategy for setting of radioactivity concentration evaluation level was prepared. In uranium processing facilities, simulation sources to apply to a validity confirmation examination of the measuring equipment were made, and these applicability and problem were studied. The method of the validity evaluation of the performance confirmation of the measuring equipment was devised by measurement experiment using this source. The manual for unexpected incidents which maintained in FY2011 was reviced by reflection of the experience of the radioactivity concentration measurement of disaster waste contaminated by the accident of Fukushima Dai-ichi NPS. JNES also supports NISA technically for the issue on influence of fall out from Fukushima Dai-ichi NPS on clearance system and NR system. In addition, the latest situation of a clearance system operated in Europe was studied. (author)

  19. Dynamic Ground Clearance

    OpenAIRE

    Hamache, Violette

    2013-01-01

    The purpose of this work is to develop a test method which will consider the variation of the ground clearance when driving, the so-called dynamic ground clearance. This has been done through the analysis of a specific application: the tractors in grain used in Brazil. Series of real life tests are run in order to obtain data on the tire compressions and the suspension travels. The tractor used is a 6x4 and is loaded with a trailer. When investigating critical cases, the minimum dynamic groun...

  20. Study on clearance system

    International Nuclear Information System (INIS)

    The clearance system is a legal system to release 'the radioactive waste not requiring treatment as radioactive waste' from the regulatory control. JNES supports Nuclear Regulatory Agency on approval and confirmation of clearance measurement and judgment developed by the operator. The objective of this study is to establish technical base of the validation method of the clearance measurement for various objects. In uranium processing facilities, simulation sources emitting alpha-rays is used in a validity confirmation examination of the measuring equipment. In this study, these sources were examined by measuring alpha and beta spectra to evaluate the applicability and problem of these sources. In addition, the measuring method detecting gamma-rays was examined. This method can be applied to complicated objects. As a part to develop a manual for unexpected incidents in clearance system, a quick method for measurement of Strontium 90 was examined. In addition, the measuring methods for the judgment of the influence of fallout and for NR (Non-Radioactive) confirmation were examined. (author)

  1. Mucociliary clearance in chronic sinusitis

    OpenAIRE

    Birdi, Surinder Mohan; Singh, Sunder; Singh, Ajit

    1998-01-01

    Mucociliary clearance is an important defence mechanism of upper and lower respiratory tracts. Any disturbance in the mechanism leads to stagnation of secretions and secondary infection with prolonged mucociliary clearance time. The present study was undertaken to establish normal mucociliary clearance time in our region and to evaluate its diagnostic and prognostic potential in chronic sinusitis of variable duration with and without obstructive diseases.

  2. Phagocytic Clearance in Neurodegeneration

    OpenAIRE

    Sokolowski, Jennifer D.; Mandell, James W.

    2011-01-01

    The cellular and molecular mechanisms of phagocytic clearance of apoptotic cells and debris have been intensely studied in invertebrate model organisms and in the mammalian immune system. This evolutionarily conserved process serves multiple purposes. Uncleared debris from dying cells or aggregated proteins can be toxic and may trigger exaggerated inflammatory responses. Even though apoptotic cell death and debris accumulation are key features of neurodegenerative diseases, relatively little ...

  3. Modelling mucociliary clearance

    OpenAIRE

    Smith, D.J.; Gaffney, E.A.; Blake, J R

    2008-01-01

    Mathematical modelling of the fluid mechanics of mucociliary clearance (MCC) is reviewed and future challenges for researchers are discussed. The morphology of the bronchial and tracheal airway surface liquid (ASL) and ciliated epithelium are briefly introduced. The cilia beat cycle, beat frequency and metachronal coordination are described, along with the rheology of the mucous layer. Theoretical modelling of MCC from the late 1960s onwards is reviewed, and distinctions between ‘phenomenolog...

  4. Site clearance working group

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The Gulf of Mexico and Louisiana continue to be areas with a high level of facility removal, and the pace of removal is projected to increase. Regulations were promulgated for the Gulf of Mexico and Louisiana requiring that abandoned sites be cleared of debris that could interfere with fishing and shrimping activities. The site clearance regulations also required verification that the sites were clear. Additionally, government programs were established to compensate fishermen for losses associated with snagging their equipment on oil and gas related objects that remained on the water bottoms in areas other than active producing sites and sites that had been verified as clear of obstructions and snags. The oil and gas industry funds the compensation programs. This paper reviews the regulations and evolving operating practices in the Gulf of Mexico and Louisiana where site clearance and fisherman`s gear compensation regulations have been in place for a number of years. Although regulations and guidelines may be in place elsewhere in the world, this paper focuses on the Gulf of Mexico and Louisiana. Workshop participants are encouraged to bring up international issues during the course of the workshop. Additionally, this paper raises questions and focuses on issues that are of concern to the various Gulf of Mexico and Louisiana water surface and water bottom stakeholders. This paper does not have answers to the questions or issues. During the workshop participants will debate the questions and issues in an attempt to develop consensus opinions and/or make suggestions that can be provided to the appropriate organizations, both private and government, for possible future research or policy adjustments. Site clearance and facility removal are different activities. Facility removal deals with removal of the structures used to produce oil and gas including platforms, wells, casing, piles, pipelines, well protection structures, etc.

  5. Family study of antipyrine clearance.

    OpenAIRE

    Blain, P G; Mucklow, J C; Wood, P; Roberts, D F; Rawlins, M D

    1982-01-01

    Antipyrine clearance was measured in 208 healthy volunteers from 78 families. After the values had been corrected for weight and sex, antipyrine clearance was observed to be significantly correlated between siblings (r = 0.590) and between spouses (r = 0.320), but not between parents and their offspring. After the clearance values had been corrected for tobacco and oral contraceptive use, there was still no significant correlation between parents and offspring. These results are incompatible ...

  6. Reforming Customs Clearance in Pakistan

    OpenAIRE

    Ahmad, Manzoor

    2010-01-01

    Simple, fast, transparent customs clearance procedures encourage trade-and the resulting tariffs and related taxes raise government revenue and stimulate economic development. After outsourcing failed to make customs more efficient or increase revenue, in 2002 Pakistan began pursuing a modern single window system for customs clearance. In 2005 the system was introduced at the port of Karac...

  7. RATIONAL CUSTOMS CLEARANCE TECHNOLOGY CHOICE

    OpenAIRE

    Shramenko, N.; Andriets, V.

    2008-01-01

    Issues concerning cargo delivery efficiencyincrease by choice of rational customs clearance technology have been considered. Three possible variants of customs clearance andmethods which allow to define the most rational version of cargo delivery in international road communication based on main efficiency criteria for definite distance have been presented.

  8. Turbomachinery Clearance Control

    Science.gov (United States)

    Chupp, Raymond E.; Hendricks, Robert C.; Lattime, Scott B.; Steinetz, Bruce M.; Aksit, Mahmut F.

    2007-01-01

    Controlling interface clearances is the most cost effective method of enhancing turbomachinery performance. Seals control turbomachinery leakages, coolant flows and contribute to overall system rotordynamic stability. In many instances, sealing interfaces and coatings are sacrificial, like lubricants, giving up their integrity for the benefit of the component. They are subjected to abrasion, erosion, oxidation, incursive rubs, foreign object damage (FOD) and deposits as well as extremes in thermal, mechanical, aerodynamic and impact loadings. Tribological pairing of materials control how well and how long these interfaces will be effective in controlling flow. A variety of seal types and materials are required to satisfy turbomachinery sealing demands. These seals must be properly designed to maintain the interface clearances. In some cases, this will mean machining adjacent surfaces, yet in many other applications, coatings are employed for optimum performance. Many seals are coating composites fabricated on superstructures or substrates that are coated with sacrificial materials which can be refurbished either in situ or by removal, stripping, recoating and replacing until substrate life is exceeded. For blade and knife tip sealing an important class of materials known as abradables permit blade or knife rubbing without significant damage or wear to the rotating element while maintaining an effective sealing interface. Most such tip interfaces are passive, yet some, as for the high-pressure turbine (HPT) case or shroud, are actively controlled. This work presents an overview of turbomachinery sealing. Areas covered include: characteristics of gas and steam turbine sealing applications and environments, benefits of sealing, types of standard static and dynamics seals, advanced seal designs, as well as life and limitations issues.

  9. Navigation Lights - USACE IENC

    Data.gov (United States)

    Department of Homeland Security — These inland electronic Navigational charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  10. Antipyrene clearance in Indian villagers.

    OpenAIRE

    Desai, N K; Sheth, U K; Mucklow, J C; Fraser, H S; Bulpitt, C J; Jones, S.W.; Dollery, C. T.

    1980-01-01

    1 Antipyrine clearance has been measured using saliva samples in 50 Maharashtrans from a village to the north of Bombay. 2 All subjects were very lean and were also anaemic probably as a result of hookworm infestation. 3 Antipyrine clearance was 36% faster than in White Londoners studied previously and more than twice as fast as in Asian immigrants living in London. 4 Clearance was 25% faster in men than in women but volume of distribution was also greater in men and mean half-lives did not d...

  11. Clearance of von Willebrand factor. : Clearance of von Willebrand factor

    OpenAIRE

    Denis, Cécile; Christophe, Olivier; Oortwijn, Beatrijs,; Lenting, Peter,

    2008-01-01

    The life cycle of von Willebrand factor (VWF) comprises a number of distinct steps, ranging from the controlled expression of the VWF gene in endothelial cells and megakaryocytes to the removal of VWF from the circulation. The various aspects of VWF clearance have been the objects of intense research in the last few years, stimulated by observations that VWF clearance is a relatively common component of the pathogenesis of type 1 von Willebrand disease (VWD). Moreover, improving the survival ...

  12. Universal navigation on smartphones

    CERN Document Server

    Karimi, Hassan A

    2011-01-01

    Universal navigation is accessible primarily through smart phones providing users with navigation information regardless of the environment (i.e., outdoor or indoor). ""Universal Navigation for Smart Phones"" provide the most up-to-date navigation technologies and systems for both outdoor and indoor navigation. It also provides a comparison of the similarities and differences between outdoor and indoor navigation systems from both a technological stand point and user's perspective. All aspects of navigation systems including geo-positioning, wireless communication, databases, and functions wil

  13. Navigation in surgery

    OpenAIRE

    Mezger, Uli; Jendrewski, Claudia; Bartels, Michael

    2013-01-01

    Introduction “Navigation in surgery” spans a broad area, which, depending on the clinical challenge, can have different meanings. Over the past decade, navigation in surgery has evolved beyond imaging modalities and bulky systems into the rich networking of the cloud or devices that are pocket-sized. Discussion This article will review various aspects of navigation in the operating room and beyond. This includes a short history of navigation, the evolution of surgical navigation, as well as t...

  14. Apollo Onboard Navigation Techniques

    Science.gov (United States)

    Interbartolo, Michael

    2009-01-01

    This viewgraph presentation reviews basic navigation concepts, describes coordinate systems and identifies attitude determination techniques including Primary Guidance, Navigation and Control System (PGNCS) IMU management and Command and Service Module Stabilization and Control System/Lunar Module (LM) Abort Guidance System (AGS) attitude management. The presentation also identifies state vector determination techniques, including PGNCS coasting flight navigation, PGNCS powered flight navigation and LM AGS navigation.

  15. Lithium clearance in chronic nephropathy

    DEFF Research Database (Denmark)

    Kamper, A L; Holstein-Rathlou, N H; Leyssac, P P;

    1989-01-01

    1. Lithium clearance measurements were made in 72 patients with chronic nephropathy of different aetiology and moderate to severely reduced renal function. 2. Lithium clearance was strictly correlated with glomerular filtration rate, and there was no suggestion of distal tubular reabsorption of...... clearance data were independent of whether renal disease was of primarily glomerular or tubular origin and, further, were not influenced by long-term conventional antihypertensive treatment. 6. It is concluded that, even with a reduced kidney function, the data are compatible with the suggestion that...... lithium clearance may be a measure of the delivery of sodium and water from the renal proximal tubule. With this assumption it was found that adjustment of the sodium excretion in chronic nephropathy initially takes place in the distal parts of the nephron (loop of Henle, distal tubule and collecting duct...

  16. Measurement of nasal mucociliary clearance.

    OpenAIRE

    Corbo, G M; Foresi, A; Bonfitto, P; Mugnano, A; Agabiti, N.; Cole, P J

    1989-01-01

    The saccharin test was carried out in a randomly selected sample of schoolchildren (142 boys and 153 girls, age range 11-14 years) to determine the variability and reproducibility of the test and to assess whether it could be used as a screening test for nasal mucociliary clearance. Nasal mucociliary clearance times were analysed according to clinical history (asthma, rhinitis, asthma with rhinitis, and acute upper respiratory tract infections), laboratory findings (positive skin test respons...

  17. Inherited Disorders of Bilirubin Clearance

    OpenAIRE

    Memon, Naureen; Weinberger, Barry I; Hegyi, Thomas; Aleksunes, Lauren M

    2015-01-01

    Inherited disorders of hyperbilirubinemia may be caused by increased bilirubin production or decreased bilirubin clearance. Reduced hepatic bilirubin clearance can be due to defective 1) unconjugated bilirubin uptake and intrahepatic storage, 2) conjugation of glucuronic acid to bilirubin (e.g. Gilbert syndrome, Crigler-Najjar syndrome, Lucey-Driscoll syndrome, breast milk jaundice), 3) bilirubin excretion into bile (Dubin-Johnson syndrome), or 4) conjugated bilirubin re-uptake (Rotor syndrom...

  18. Method of mucociliary clearance assessment

    Science.gov (United States)

    Danilova, Tatiana V.; Manturov, Alexey O.; Ermakov, Igor Y.; Mareev, Gleb O.; Mareev, Oleg V.

    2016-04-01

    The article is devoted to the research capabilities of mucociliary clearance in the nasal cavity and paranasal sinuses using modern techniques of digital video recording and processing. We describe the setup and software for this method and the results of our research. Using microscope and digital camera we can provide a good method to study mucociliary clearance and by usage of special software we able to measure some characteristic of nasal mucosae and its main function.

  19. Re-entry flight clearance

    OpenAIRE

    Juliana, S.

    2006-01-01

    The objective of the research was to identify and evaluate promising mathematical techniques for re-entry flight clearance. To fulfil this objective, two mathematical methods were investigated and developed: μ analysis for linear models and interval analysis for both linear and non-linear models. The stability of re-entry vehicles in the presence of model uncertainties was chosen as the clearance criterion, which is represented by two mathematical criteria: worst-case eigenvalues (linear...

  20. Robotic Mounted Detection System: robotics for route clearance

    Science.gov (United States)

    Hutchison, John; Klager, Gene; McCoy, Edward; Fite, David; Frederick, Brian

    2010-04-01

    Robotic Mounted Detection System (RMDS) is a government program to enable robotic control of a Husky route clearance vehicle with a mine detection sensor payload. The goal is for the operator to control the Husky and mine detection sensor from another vehicle. This program will provide the user with standard tele-operation control of the vehicle as well as semi-autonomous modes including cruise control, precision waypoint navigation with operator error correction and a visual mode allowing the operator to enter waypoints in the current video feed. The use of autonomy will be tailored to give the operator maximum control of the robotic vehicle's path while minimizing the effort required to maintain the desired route. Autonomous alterations of the path would conflict with the goal of route clearance, so waypoint navigation will allow the operator to supply offsets to counteract location errors. While following a waypoint path, the Husky will be capable of controlling its speed to maintain an operator specified distance from the control vehicle. Obstacle avoidance will be limited to protecting the mine detection sensor, leaving any decision to leave the path up to the operator. Video will be the primary navigational sensor feed to the operator, who will use an augmented steering wheel controller and computer display to control the Husky. A LADAR system will be used to detect obstacles that could damage the mine sensor and to maintain the optimal sensor orientation while the vehicle is moving. Practical issues and lessons learned during integration will be presented.

  1. Optical Navigation System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is for a flexible navigation system for deep space operations that does not require GPS measurements. The navigation solution is computed using an...

  2. Lithium clearance in chronic nephropathy

    DEFF Research Database (Denmark)

    Kamper, A L; Holstein-Rathlou, N H; Leyssac, P P;

    1989-01-01

    1. Lithium clearance measurements were made in 72 patients with chronic nephropathy of different aetiology and moderate to severely reduced renal function. 2. Lithium clearance was strictly correlated with glomerular filtration rate, and there was no suggestion of distal tubular reabsorption of...... lithium or influence of osmotic diuresis. 3. Fractional reabsorption of lithium was reduced in most patients with glomerular filtration rates below 25 ml/min. 4. Calculated fractional distal reabsorption of sodium was reduced in most patients with glomerular filtration rates below 50 ml/min. 5. Lithium...... lithium clearance may be a measure of the delivery of sodium and water from the renal proximal tubule. With this assumption it was found that adjustment of the sodium excretion in chronic nephropathy initially takes place in the distal parts of the nephron (loop of Henle, distal tubule and collecting duct...

  3. Lactate clearance in cardiorespiratory emergency

    Directory of Open Access Journals (Sweden)

    Serena Greco

    2007-08-01

    Full Text Available Early goal directed therapy has been found to improve prognosis in septic patients, if the therapeutic goal is achieved within the first six hours. The aim of our study is to demonstrate that in patients with acute cardiorespiratory failure, rapid (within 2 hours lactate clearance can help define patients’ prognosis. 67 consecutive patients, admitted to our 16-bed Emergency Medicine ward for acute cardiorespiratory failure (age 75,9 ± 9,8 (APACHE II score 19,0 ± 4,1, were included in the study. Blood lactate concentration was read at admission and after 2, 6 and 24 hours. We evaluated mortality at seven days and the use of orotracheal intubation (patients with negative outcome vs. discharge or transfer to a non-emergency ward with subsequent discharge (patients with negative outcome. Lactate concentration at admission was 4,6 ± 2,5 mmol/l; lactate clearance (% at 2 hours was 40,4 ± 32,1 in patients with a positive outcome and –8,3 ± 5,0 in patients with a negative outcome (p < 0,05. Lactate clearance at 2 hours < 25% is correlated to a negative outcome with an 84,2% sensitivity and a 79,2% specificity. The positive predictive value was 61,5% and the negative predictive value was 92,2%. Systematic lactate clearance monitoring can be used in cases of acute cardiorespiratory insufficiency to identify patients with a high risk of negative outcome. In our study, low clearance at two hours was associated with an increase in mortality and/or the need for orotracheal intubation. Conversely, a clearance at two hours of > 25% in most cases confirms the therapeutic strategy undertaken. Serial evaluation of blood lactate concentration may therefore be useful in guiding treatment strategies.

  4. Inherited Disorders of Bilirubin Clearance

    Science.gov (United States)

    Memon, Naureen; Weinberger, Barry I; Hegyi, Thomas; Aleksunes, Lauren M

    2016-01-01

    Inherited disorders of hyperbilirubinemia may be caused by increased bilirubin production or decreased bilirubin clearance. Reduced hepatic bilirubin clearance can be due to defective 1) unconjugated bilirubin uptake and intrahepatic storage, 2) conjugation of glucuronic acid to bilirubin (e.g. Gilbert syndrome, Crigler-Najjar syndrome, Lucey-Driscoll syndrome, breast milk jaundice), 3) bilirubin excretion into bile (Dubin-Johnson syndrome), or 4) conjugated bilirubin re-uptake (Rotor syndrome). In this review, the molecular mechanisms and clinical manifestations of these conditions are described, as well as current approaches to diagnosis and therapy. PMID:26595536

  5. Radar and electronic navigation

    CERN Document Server

    Sonnenberg, G J

    2013-01-01

    Radar and Electronic Navigation, Sixth Edition discusses radar in marine navigation, underwater navigational aids, direction finding, the Decca navigator system, and the Omega system. The book also describes the Loran system for position fixing, the navy navigation satellite system, and the global positioning system (GPS). It reviews the principles, operation, presentations, specifications, and uses of radar. It also describes GPS, a real time position-fixing system in three dimensions (longitude, latitude, altitude), plus velocity information with Universal Time Coordinated (UTC). It is accur

  6. Research on Web Navigations

    Directory of Open Access Journals (Sweden)

    Qian Zhongsheng

    2011-10-01

    Full Text Available Web applications employ various new languages, technologies, and programming models to implement applications with very high quality requirements. In building Web applications, three types of models must be considered, which are conceptual model, navigation model and presentation model. Navigation problems are significant among them that must be confronted. This work illuminates three different classifications of Web navigations as well as their feature, analyzes and compares various popular Web navigation models. Moreover, it also presents and suggests some guidelines for Web navigation design based on Web development design pattern experiences.

  7. Noninvasive clearance of airway secretions.

    Science.gov (United States)

    Hardy, K A; Anderson, B D

    1996-06-01

    Airway clearance techniques are indicated for specific diseases that have known clearance abnormalities (Table 2). Murray and others have commented that such techniques are required only for patients with a daily sputum production of greater than 30 mL. The authors have observed that patients with diseases known to cause clearance abnormalities can have sputum clearance with some techniques, such as positive expiratory pressure, autogenic drainage, and active cycle of breathing techniques, when PDPV has not been effective. Hasani et al has shown that use of the forced exhalatory technique in patients with nonproductive cough still resulted in movement of secretions proximally from all regions of the lung in patients with airway obstruction. It is therefore reasonable to consider airway clearance techniques for any patient who has a disease known to alter mucous clearance, including CF, dyskinetic cilia syndromes, and bronchiectasis from any cause. Patients with atelectasis from mucous plugs and hypersecretory states, such as asthma and chronic bronchitis, patients with pain secondary to surgical procedures, and patients with neuromuscular disease, weak cough, and abnormal patency of the airway may also benefit from the application of airway clearance techniques. Infants and children up to 3 years of age with airway clearance problems need to be treated with PDPV. Manual percussion with hands alone or a flexible face mask or cup and small mechanical vibrator/percussors, such as the ultrasonic devices, can be used. The intrapulmonary percussive ventilator shows growing promise in this area. The high-frequency oscillator is not supplied with vests of appropriate sizes for tiny babies and has not been studied in this group. Young patients with neuromuscular disease may require assisted ventilation and airway oscillations can be applied. CPAP alone has been shown to improve achievable flow rates that will increase air-liquid interactions for patients with these diseases

  8. Dynamic clearance measure to evaluate locomotor and perceptuo-motor strategies used for obstacle circumvention in a virtual environment.

    Science.gov (United States)

    Darekar, Anuja; Lamontagne, Anouk; Fung, Joyce

    2015-04-01

    Circumvention around an obstacle entails a dynamic interaction with the obstacle to maintain a safe clearance. We used a novel mathematical interpolation method based on the modified Shepard's method of Inverse Distance Weighting to compute dynamic clearance that reflected this interaction as well as minimal clearance. This proof-of-principle study included seven young healthy, four post-stroke and four healthy age-matched individuals. A virtual environment designed to assess obstacle circumvention was used to administer a locomotor (walking) and a perceptuo-motor (navigation with a joystick) task. In both tasks, participants were asked to navigate towards a target while avoiding collision with a moving obstacle that approached from either head-on, or 30° left or right. Among young individuals, dynamic clearance did not differ significantly between obstacle approach directions in both tasks. Post-stroke individuals maintained larger and smaller dynamic clearance during the locomotor and the perceptuo-motor task respectively as compared to age-matched controls. Dynamic clearance was larger than minimal distance from the obstacle irrespective of the group, task and obstacle approach direction. Also, in contrast to minimal distance, dynamic clearance can respond differently to different avoidance behaviors. Such a measure can be beneficial in contrasting obstacle avoidance behaviors in different populations with mobility problems. PMID:25682376

  9. 49 CFR 192.325 - Underground clearance.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 3 2010-10-01 2010-10-01 false Underground clearance. 192.325 Section 192.325... Lines and Mains § 192.325 Underground clearance. (a) Each transmission line must be installed with at least 12 inches (305 millimeters) of clearance from any other underground structure not associated...

  10. 32 CFR 154.48 - Issuing clearance.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Issuing clearance. 154.48 Section 154.48 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE SECURITY DEPARTMENT OF DEFENSE PERSONNEL SECURITY PROGRAM REGULATION Issuing Clearance and Granting Access § 154.48 Issuing clearance. (a) Authorities designated in paragraph...

  11. 30 CFR 56.11010 - Stairstep clearance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Stairstep clearance. 56.11010 Section 56.11010 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Travelways § 56.11010 Stairstep clearance. Vertical clearance...

  12. 14 CFR 25.925 - Propeller clearance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Propeller clearance. 25.925 Section 25.925 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Powerplant General § 25.925 Propeller clearance. Unless smaller clearances are substantiated,...

  13. 76 FR 47917 - Lead; Clearance and Clearance Testing Requirements for the Renovation, Repair, and Painting Program

    Science.gov (United States)

    2011-08-05

    ... August 5, 2011 Part IV Environmental Protection Agency 40 CFR Part 745 Lead; Clearance and Clearance... AGENCY 40 CFR Part 745 RIN 2070-AJ57 Lead; Clearance and Clearance Testing Requirements for the... 2008 Lead Renovation, Repair, and Painting Program (RRP) rule, the EPA agreed to propose a number...

  14. Navigating the Internet.

    OpenAIRE

    Powsner, S M; Roderer, N K

    1994-01-01

    Navigating any complex set of information resources requires tools for both browsing and searching. A number of tools are available today for using Internet resources, and more are being developed. This article reviews existing navigational tools, including two developed at the Yale University School of Medicine, and points out their strengths and weaknesses. A major shortcoming of the present Internet navigation methods is the lack of controlled descriptions of the available resources. As a ...

  15. Indoor wayfinding and navigation

    CERN Document Server

    2015-01-01

    Due to the widespread use of navigation systems for wayfinding and navigation in the outdoors, researchers have devoted their efforts in recent years to designing navigation systems that can be used indoors. This book is a comprehensive guide to designing and building indoor wayfinding and navigation systems. It covers all types of feasible sensors (for example, Wi-Fi, A-GPS), discussing the level of accuracy, the types of map data needed, the data sources, and the techniques for providing routes and directions within structures.

  16. Impaired tracheobronchial clearance in bronchiectasis.

    OpenAIRE

    Currie, D C; Pavia, D; Agnew, J E; Lopez-Vidriero, M T; Diamond, P D; Cole, P J; Clarke, S. W.

    1987-01-01

    Tracheobronchial clearance was measured by a radioaerosol technique in 12 patients with bronchiectasis, seven patients with chronic obstructive lung disease expectorating mucoid sputum daily (group X), eight patients with chronic obstructive lung disease but negligible sputum expectoration (group Y), and 10 healthy subjects. The patients with bronchiectasis all expectorated purulent sputum daily (mean wet weight 47 g/day), had reduced forced expiratory volume in one second (FEV1) (mean 47.5% ...

  17. Navigation Using Inertial Sensors

    OpenAIRE

    Groves, P. D.

    2015-01-01

    This tutorial provides an introduction to navigation using inertial sensors, explaining the underlying principles. Topics covered include accelerometer and gyro technology and their characteristics, strapdown inertial navigation, attitude determination, integration and alignment, zero updates, motion constraints, pedestrian dead reckoning using step detection, and fault detection.

  18. Development of the clearance level verification evaluation system. 2. Construction of the clearance data management system

    International Nuclear Information System (INIS)

    Clearance is defined as the removal of radioactive materials or radioactive objects within authorized practices from any further regulatory control by the regulatory body. In Japan, clearance level and a procedure for its verification has been introduced under the Laws and Regulations, and solid clearance wastes inspected by the national authority can be handled and recycled as normal wastes. The most prevalent type of wastes have generated from the dismantling of nuclear facilities, so the Japan Atomic Energy Agency (JAEA) has been developing the Clearance Level Verification Evaluation System (CLEVES) as a convenient tool. The Clearance Data Management System (CDMS), which is a part of CLEVES, has been developed to support measurement, evaluation, making and recording documents with clearance level verification. In addition, validation of the evaluation result of the CDMS was carried out by inputting the data of actual clearance activities in the JAEA. Clearance level verification is easily applied by using the CDMS for the clearance activities. (author)

  19. Comparing taxi clearance input layouts for advancements in flight deck automation for surface operations

    Science.gov (United States)

    Cheng, Lara W. S.

    Airport moving maps (AMMs) have been shown to decrease navigation errors, increase taxiing speed, and reduce workload when they depict airport layout, current aircraft position, and the cleared taxi route. However, current technologies are limited in their ability to depict the cleared taxi route due to the unavailability of datacomm or other means of electronically transmitting clearances from ATC to the flight deck. This study examined methods by which pilots can input ATC-issued taxi clearances to support taxi route depictions on the AMM. Sixteen general aviation (GA) pilots used a touchscreen monitor to input taxi clearances using two input layouts, softkeys and QWERTY, each with and without feedforward (graying out invalid inputs). QWERTY yielded more taxi route input errors than the softkeys layout. The presence of feedforward did not produce fewer taxi route input errors than in the non-feedforward condition. The QWERTY layout did reduce taxi clearance input times relative to the softkeys layout, but when feedforward was present this effect was observed only for the longer, 6-segment taxi clearances. It was observed that with the softkeys layout, feedforward reduced input times compared to non-feedforward but only for the 4-segment clearances. Feedforward did not support faster taxi clearance input times for the QWERTY layout. Based on the results and analyses of the present study, it is concluded that for taxi clearance inputs, (1) QWERTY remain the standard for alphanumeric inputs, and (2) feedforward be investigated further, with a focus on participant preference and performance of black-gray contrast of keys.

  20. Lactate clearance in cardiorespiratory emergency

    OpenAIRE

    Serena Greco; Giovanna Guiotto; Antonino Maffei; Stefania Martino; Giuseppe Romano; Fernando Schiraldi

    2007-01-01

    Early goal directed therapy has been found to improve prognosis in septic patients, if the therapeutic goal is achieved within the first six hours. The aim of our study is to demonstrate that in patients with acute cardiorespiratory failure, rapid (within 2 hours) lactate clearance can help define patients’ prognosis. 67 consecutive patients, admitted to our 16-bed Emergency Medicine ward for acute cardiorespiratory failure (age 75,9 ± 9,8) (APACHE II score 19,0 ± 4,1), we...

  1. Algorithms for vehicle navigation

    OpenAIRE

    Storandt, Sabine

    2012-01-01

    Nowadays, navigation systems are integral parts of most cars. They allow the user to drive to a preselected destination on the shortest or quickest path by giving turn-by-turn directions. To fulfil this task the navigation system must be aware of the current position of the vehicle at any time, and has to compute the optimal route to the destination on that basis. Both of these subproblems have to be solved frequently, because the navigation system must react immediately if the vehicle leaves...

  2. Restricted Navigation Areas - USACE IENC

    Data.gov (United States)

    Department of Homeland Security — These inland electronic Navigational charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  3. The Clearance of Cyclosporine by Hemodialysis

    OpenAIRE

    Venkataramanan, Raman; Ptachcinski, Richard J.; Burckart, Gilbert J.; YANG, SHIN L.; Starzl, Thomas E.; VAN THEIL, DAVID H.

    1984-01-01

    The pharmacokinetics of cyclosporine were studied in five liver transplant patients when they were on and off hemodialysis. There was no significant difference in the blood clearance of cyclosporine between these two periods. Less than 1 per cent of the dose of cyclosporine was recovered in the dialysate. The mean dialysis clearance was less than 1 ml/min. This represents less than 1 per cent of the total blood clearance of cyclosporine. Dosage alterations of cyclosporine during or after hemo...

  4. Revolute joints with clearance in multibody systems

    OpenAIRE

    Flores, Paulo; Ambrósio, Jorge

    2004-01-01

    A computational methodology for dynamic analysis of multibody mechanical systems with joint clearance is presented in this work. Clearances always exist in real joints in order to ensure the correct relative motion between the connected bodies being the gap associated to them a result of machining tolerance, wear, and local deformations. Clearance at different joints is the source for impact forces, resulting in wear and tear of the joints, and consequently the degradation of the system perfo...

  5. Spatial cognition and navigation

    Science.gov (United States)

    Aretz, Anthony J.

    1989-01-01

    An experiment that provides data for the development of a cognitive model of pilot flight navigation is described. The experiment characterizes navigational awareness as the mental alignment of two frames of reference: (1) the ego centered reference frame that is established by the forward view out of the cockpit and (2) the world centered reference frame that is established by the aircraft's location on a map. The data support a model involving at least two components: (1) the perceptual encoding of the navigational landmarks and (2) the mental rotation of the map's world reference frame into alignment with the ego centered reference frame. The quantitative relationships of these two factors are provided as possible inputs for a computational model of spatial cognition during flight navigation.

  6. Mucociliary clearance in early simple chronic bronchitis

    International Nuclear Information System (INIS)

    Tracheobronchial mucociliary clearance was measured in 37 patients with early simple chronic bronchitis. A non-invasive radio-aerosol technique with inhalation of 99Tcm labelled 5-μm polystyrene particles followed by assessment of radio-nuclide distribution by posterior gamma-camera scans was employed. The mucociliary clearance of the bronchitics was significantly slower than clearance of a non-smoker control group. An interim analysis of the effect of treatment with a surfactant stimulating drug, ambroxol, suggested a dosage-dependent tendency to a faster mucociliary clearance than seen in placebo-treated bronchitics. (author)

  7. Symmetric Synchronous Collaborative Navigation

    OpenAIRE

    Gerosa, Luca; Giordani, Alessandra; Ronchetti, Marco

    2004-01-01

    Synchronous collaborative navigation is a form of social navigation where users virtually share a web browser. In this paper, we present a symmetric, proxy-based architecture where each user can take the lead and guide others in visiting web sites, without the need for a special browser or other software. We show how we have applied this scheme to a problem-solving-oriented e-learning system.

  8. 30 CFR 56.7018 - Hand clearance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand clearance. 56.7018 Section 56.7018 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Drilling § 56.7018 Hand clearance....

  9. Cortisol does not inhibit prednisolone clearance.

    OpenAIRE

    Meffin, P J; Sallustio, B C; Purdie, Y J; Robson, R A; Wing, L M; Brooks, P M

    1985-01-01

    The disposition of prednisolone has been studied in eight male subjects with and without the concomitant administration of cortisol which produced plasma cortisol concentrations 10-fold higher than endogenous levels. The clearance and steady-state distribution volume of total prednisolone were increased as was the prednisolone free fraction but the clearance of unbound prednisolone was unaltered by cortisol co-administration.

  10. 30 CFR 56.11008 - Restricted clearance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Restricted clearance. 56.11008 Section 56.11008 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-SURFACE METAL AND NONMETAL MINES Travelways § 56.11008 Restricted clearance. Where...

  11. 28 CFR 524.74 - Activities clearance.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Activities clearance. 524.74 Section 524.74 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INMATE ADMISSION, CLASSIFICATION, AND TRANSFER CLASSIFICATION OF INMATES Central Inmate Monitoring (CIM) System § 524.74 Activities clearance. (a) Except as provided for in...

  12. 14 CFR 23.925 - Propeller clearance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Propeller clearance. 23.925 Section 23.925 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Powerplant General § 23.925 Propeller clearance. Unless...

  13. Beginnings of Satellite Navigation

    Directory of Open Access Journals (Sweden)

    Miljenko Solarić

    2008-05-01

    Full Text Available The first satellite navigation system called the Navy Navigation Satellite System (NNSS or TRANSIT was planned in the USA in 1958. It consisted of 5-6 artificial Earth satellites, was set in motion for the USA military in 1964, and in 1967 for civilian purposes. The frequency shift of received radio waves emitted from the satellite and caused by the Doppler effect was measured. The TRANSIT satellite speed of approaching or moving away was derived from that; the TRANSIT satellites emmited also their own coordinates. Then the ship's position was determined by an intersection of three hyperboloids, which were determined from differences of distances in three time intervals. Maintenance of this navigation system was stopped in 1996, but it is still being used in the USA Navy for exploring the ionosphere. Furthermore, results of Doppler measurements in international projects at the Hvar Observatory from 1982 and 1983. This was the first time in Croatia and the former country that the coordinates of the Hvar Observatory were determined in the unique world coordinate system WGS'72. The paper ends with a brief representation of the Tsiklon Doppler navigation system produced in the former Soviet Union, and there is a list of some of numerous produced and designed satellite navigation systems.Ključne riječi

  14. Coordinating sensing and local navigation

    Science.gov (United States)

    Slack, Marc G.

    1991-07-01

    Based on Navigation Templates (or NaTs), this work presents a new paradigm for local navigation which addresses the noisy and uncertain nature of sensor data. Rather than creating a new navigation plan each time the robot's perception of the world changes, the technique incorporates perceptual changes directly into the existing navigation plan. In this way, the robot's navigation plan is quickly and continuously modified, resulting in actions that remain coordinated with its changing perception of the world.

  15. Mobile Robot Navigation

    DEFF Research Database (Denmark)

    Andersen, Jens Christian

    2007-01-01

    . The research is now progressing towards autonomous robots which will be able to assist us in our daily life. One of the enabling technologies is navigation, and navigation is the subject of this thesis. Navigation of an autonomous robot is concerned with the ability of the robot to direct itself from...... validation of the implemented solutions and the ability of the methods to solve real world problems. The amount of software needed by an autonomous robot can be overwhelming. Software reuse and distributed development are therefore important issues. The thesis describes a new component architecture......Abstract Robots will soon take part in everyone’s daily life. In industrial production this has been the case for many years, but up to now the use of mobile robots has been limited to a few and isolated applications like lawn mowing, surveillance, agricultural production and military applications...

  16. Navigating Distributed Services

    DEFF Research Database (Denmark)

    Beute, Berco

    2002-01-01

    , to a situation where they are distributedacross the Internet. The second trend is the shift from a virtual environment that solelyconsists of distributed documents to a virtual environment that consists of bothdistributed documents and distributed services. The third and final trend is theincreasing...... diversity of devices used to access information on the Internet.The focal point of the thesis is an initial exploration of the effects of the trends onusers as they navigate the virtual environment of distributed documents and services.To begin the thesis uses scenarios as a heuristic device to identify and...... analyse themain effects of the trends. This is followed by an exploration of theory of navigationInformation Spaces, which is in turn followed by an overview of theories, and the stateof the art in navigating distributed services. These explorations of both theory andpractice resulted in a large number of...

  17. Mariner 9 navigation

    Science.gov (United States)

    Neil, W. J.; Jordan, J. F.; Zielenbach, J. W.; Wong, S. K.; Mitchell, R. T.; Webb, W. A.; Koskela, P. E.

    1973-01-01

    A final, comprehensive description of the navigation of Mariner 9-the first U.S. spacecraft to orbit another planet is provided. The Mariner 9 navigation function included not only precision flight path control but also pointing of the spacecraft's scientific instruments mounted on a two degree of freedom scan platform. To the extent appropriate, each section describes the perflight analyses on which the operational strategies and performance predictions were based. Inflight results are then discussed and compared with the preflight predictions. Postflight analyses, which were primarily concerned with developing a thorough understanding of unexpected in-flight results, are also presented.

  18. The attack navigator

    DEFF Research Database (Denmark)

    Probst, Christian W.; Willemson, Jan; Pieters, Wolter

    2016-01-01

    The need to assess security and take protection decisions is at least as old as our civilisation. However, the complexity and development speed of our interconnected technical systems have surpassed our capacity to imagine and evaluate risk scenarios. This holds in particular for risks that are...... caused by the strategic behaviour of adversaries. Therefore, technology-supported methods are needed to help us identify and manage these risks. In this paper, we describe the attack navigator: a graph-based approach to security risk assessment inspired by navigation systems. Based on maps of a socio...

  19. GPS INTEGRATED NAVIGATION SYSTEM

    Directory of Open Access Journals (Sweden)

    Swati R. Dhabarde

    2012-06-01

    Full Text Available In my project I am developing a computer program that willsimulate and explain the need of technology and advance systemfor any person moving or navigating in a car (or any vehicle.Every person in day to day life requires some navigation for theproper working of his work .it is the human nature that ever mantakes some guidance about some or another work without guidancethe job taken by a human being will be completed properly or notis not known. So, for a proper working of your decided scheduleyou should know everything about the place where you live. Youdo know and if you ought to know then you can use “EmergencyNavigation System”.‘Emergency Navigation System’ is specialized softwarewhich is able to track the current position (of any person drivingvehicles and tell the path and other detailed information aboutyour destination. If there are occurrences of multiple paths to thesame destination then it can show the shortest one among them.

  20. Influence of chronic dosing on theophylline clearance.

    OpenAIRE

    Efthimiou, H; Morgan, D. J.; Ioannides-Demos, L; Raymond, K.; McLean, A. J.

    1984-01-01

    Theophylline clearance was studied in normal healthy volunteers before and after chronic oral dosing. Oral theophylline clearance showed a significant decrease (P less than 0.001) from 59.3 +/- 6.48 ml/min (mean +/- s.e. mean, n = 10) to 48.0 +/- 6.4 ml/min. Steady-state intravenous clearance decreased by 26 +/- 2% from 55.1 +/- 7.7 ml/min to 41.0 +/- 5.96 ml/min (mean +/- s.e. mean, n = 6; P less than 0.001) at constant steady-state intravenous test concentrations (mean 15.0 +/- 1.6 microgra...

  1. SKIN KINETICS AND DERMAL CLEARANCE

    Directory of Open Access Journals (Sweden)

    Prakash Shashi

    2012-08-01

    Full Text Available Availability of several therapeutic and cosmetic formulations for topical application has made the research on skin kinetics as a topic of current interest. Topical formulations are typically meant for local effect although there is always a chance that the low molecular weight chemicals are easily transported across the skin layer and make it available in the systemic circulation. Thus there is a major concern about the transport of chemical moieties following the topical application of cosmetics and therapeutic formulations and the real time measurement of the molecules in the skin layer has become obligatory. It is well known that the properties of both drug and the excipients have identical role in determining the skin permeability of chemical moieties. In the last decade several investigations have been carried out in this filed using several in vitro and in vivo models. This review provides a brief account on the basics of skin kinetics, parameters assessed, various techniques and methods adapted in skin kinetic studies. Moreover, we have also discussed about the micro-environment inside the skin layer and the possible mechanism of drug depot formation, skin metabolism and clearance of molecules from the skin layers.

  2. Nucleotide-mediated airway clearance.

    Science.gov (United States)

    Schmid, Andreas; Clunes, Lucy A; Salathe, Mathias; Verdugo, Pedro; Dietl, Paul; Davis, C William; Tarran, Robert

    2011-01-01

    A thin layer of airway surface liquid (ASL) lines the entire surface of the lung and is the first point of contact between the lung and the environment. Surfactants contained within this layer are secreted in the alveolar region and are required to maintain a low surface tension and to prevent alveolar collapse. Mucins are secreted into the ASL throughout the respiratory tract and serve to intercept inhaled pathogens, allergens and toxins. Their removal by mucociliary clearance (MCC) is facilitated by cilia beating and hydration of the ASL by active ion transport. Throughout the lung, secretion, ion transport and cilia beating are under purinergic control. Pulmonary epithelia release ATP into the ASL which acts in an autocrine fashion on P2Y(2) (ATP) receptors. The enzymatic network describes in Chap. 2 then mounts a secondary wave of signaling by surface conversion of ATP into adenosine (ADO), which induces A(2B) (ADO) receptor-mediated responses. This chapter offers a comprehensive description of MCC and the extensive ramifications of the purinergic signaling network on pulmonary surfaces. PMID:21560046

  3. Deposition of aerosols and bronchial clearance measurements

    International Nuclear Information System (INIS)

    A special inhalative device is described for reproducible deposition patterns of radioactive aerosols to measure mucociliary and tussive clearance and to evaluate the effect of drugs on the bronchial tree is described. Additive actions on mucus transport exist between β2-agonists and theophylline, but not incombination with inhalative quarternary ammonium compounds (ipatropium and oxitropium bromide). Mucolytics are generally less effective on mucociliary clearance than β2-agonists and theophylline, positive, negative and nonresponders are ofter seen due to the different viscoelastic properties of the mucus. Mucus transport is more than mucociliary clearance. Two-phase gas/liquid movement and coughing are also important transport mechanisms for bronchial mucus. Therefore, bronchodilators enhance mucus transport by increasing airway patency, which increases total and regional air flow and improves cough clearance. (orig.)

  4. Compressor airfoil tip clearance optimization system

    Energy Technology Data Exchange (ETDEWEB)

    Little, David A.; Pu, Zhengxiang

    2015-08-18

    A compressor airfoil tip clearance optimization system for reducing a gap between a tip of a compressor airfoil and a radially adjacent component of a turbine engine is disclosed. The turbine engine may include ID and OD flowpath boundaries configured to minimize compressor airfoil tip clearances during turbine engine operation in cooperation with one or more clearance reduction systems that are configured to move the rotor assembly axially to reduce tip clearance. The configurations of the ID and OD flowpath boundaries enhance the effectiveness of the axial movement of the rotor assembly, which includes movement of the ID flowpath boundary. During operation of the turbine engine, the rotor assembly may be moved axially to increase the efficiency of the turbine engine.

  5. Clearance of germ granules in the soma

    OpenAIRE

    Sugimoto, Asako

    2009-01-01

    Germ granules are ribonucleoprotein complexes specifically segregated into germ cell lineages in diverse organisms. Recent studies indicate that multiple mechanisms are involved in the clearance of germ granules and their components in somatic cells in Caenorhabditis elegans embryos.

  6. Glial K(+) Clearance and Cell Swelling

    DEFF Research Database (Denmark)

    Macaulay, Nanna; Zeuthen, Thomas

    2012-01-01

    space into the glial cell are debated. Although spatial buffer currents may occur, their quantitative contribution to K(+) clearance is uncertain. The concept of spatial buffering of K(+) precludes intracellular K(+) accumulation and is therefore (i) difficult to reconcile with the K(+) accumulation...... repeatedly observed in glial cells during K(+) clearance and (ii) incompatible with K(+)-dependent glial cell swelling. K(+) uptake into non-voltage clamped cultured glial cells is carried out by the Na(+)/K(+)-ATPase and the Na(+)/K(+)/Cl(-) cotransporter in combination. In brain slices and intact optic...... nerve, however, only the Na(+)/K(+)-ATPase has been demonstrated to be involved in stimulus-evoked K(+) clearance. The glial cell swelling associated with K(+) clearance is prevented under conditions that block the activity of the Na(+)/K(+)/Cl(-) cotransporter. The Na(+)/K(+)/Cl(-) cotransporter is...

  7. The curious world of apoptotic cell clearance

    OpenAIRE

    Weitzman, Jonathan B

    2004-01-01

    Analysis of knockout mice has brought into question the previously proposed role of the phosphatidylserine receptor (Ptdsr) in the clearance of apoptotic cell corpses, and has suggested important functions in regulating differentiation and inflammation.

  8. Exclusion, exemption, clearance European Union approach

    International Nuclear Information System (INIS)

    The presentation overviews the following issues: Euratom Basic Safety Standards; administrative requirements; radiation protection of the population. Scope of the Standards: natural radiation sources; exclusion. Exemption; Clearance; Import of radioactive scrap metal

  9. Inland Electronic Navigational Charts (IENC)

    Data.gov (United States)

    Army Corps of Engineers, Department of the Army, Department of Defense — These Inland Electronic Navigational Charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  10. Nautical Navigation Aids (NAVAID) Locations

    Data.gov (United States)

    Department of Homeland Security — Structures intended to assist a navigator to determine position or safe course, or to warn of dangers or obstructions to navigation. This dataset includes lights,...

  11. Blade by Blade Tip Clearance Measurement

    OpenAIRE

    A. G. Sheard

    2011-01-01

    This paper describes a capacitance-based tip clearance measurement system which engineers have used in the most demanding turbine test applications. The capacitance probe has survived extended use in a major European gas turbine manufacturer's high-temperature demonstrator unit, where it functioned reliably at a turbine entry temperature in excess of 1800 degrees Kelvin. This paper explores blade by blade tip clearance measurement techniques and examines probe performance under laboratory con...

  12. Clearance of inhaled particles in ankylosing spondylitis.

    OpenAIRE

    Farquhar, D R; Chamberlain, M. J.; McCain, G A; Morgan, W K

    1989-01-01

    Patients with ankylosing spondylitis may uncommonly develop apical fibrobullous lung disease, the cause of which is unknown. It is postulated here that rigidity of the thoracic cage leads to reduced apical clearance of inhaled particles and may thereby predispose to chronic infection. Deposition and clearance of inhaled technetium-99m sulphur colloid particles were studied in eight male patients with ankylosing spondylitis who had chest wall rigidity (mean (SD) chest expansion 1.8 (1.07) cm) ...

  13. Reduction of antipyrine clearance in psoriasis.

    OpenAIRE

    Marsden, J R; Williams, F M; Keys, B; Rawlins, M D; Shuster, S

    1984-01-01

    Antipyrine clearance was determined in 41 psoriatics and age-sex matched controls, using sequential measurements of salivary concentration. Antipyrine clearance and elimination rate constant were less in psoriatics (P less than 0.05) and apparent volumes of distribution were similar. These differences were greater between female psoriatics and controls (P less than 0.025; P less than 0.05) and the differences between male psoriatics and controls were not significant. Correlation of simultaneo...

  14. Extreme contagion in global habitat clearance

    OpenAIRE

    Boakes, Elizabeth H.; Mace, Georgina M; Philip J K McGowan; Fuller, Richard A.

    2009-01-01

    Habitat clearance remains the major cause of biodiversity loss, with consequences for ecosystem services and for people. In response to this, many global conservation schemes direct funds to regions with high rates of recent habitat destruction, though some also emphasize the conservation of remaining large tracts of intact habitat. If the pattern of habitat clearance is highly contagious, the latter approach will help prevent destructive processes gaining a foothold in areas of contiguous in...

  15. Hemodialysis clearance of metronidazole and its metabolites.

    OpenAIRE

    Lau, A. H.; Chang, C W; Sabatini, S

    1986-01-01

    Metronidazole is now being used with increasing frequency for various infectious conditions in patients with renal failure. It is commonly administered to septic patients who have developed acute renal failure requiring hemodialysis. The hemodialysis clearances of metronidazole and its metabolites were evaluated in nine renal failure patients on maintenance hemodialysis. The mean +/- standard deviation clearance and the extraction ratio were 106.9 +/- 16.3 ml/min and 0.65 +/- 0.08, respective...

  16. Navigation in Virtual Environment

    Czech Academy of Sciences Publication Activity Database

    Mikeš, Stanislav; Haindl, Michal; Holub, Radek

    Vienna: Austrian Computer Society, 2008 - (R. Sablatnig and J. Hemsley and P. Krammerer and E. Zolda and J. Stockinger), s. 111-118 ISBN 978-3-85403-238-0. [2nd International Conference EVA. Vienna (AT), 25.08.2008-28.08.2008] R&D Projects: GA AV ČR 1ET400750407; GA MŠk 1M0572; GA ČR GA102/08/0593 Grant ostatní: GA MŠk(CZ) 2C06019 Institutional research plan: CEZ:AV0Z10750506 Keywords : Virtual Reality * Navigation Subject RIV: BD - Theory of Information http://library.utia.cas.cz/separaty/2008/RO/mikes-haindl-holub-navigation%20in%20virtual%20environment.pdf

  17. Mobile Robot Navigation

    OpenAIRE

    Andersen, Jens Christian; Ravn, Ole; Andersen, Nils Axel

    2007-01-01

    Robotter vil om få år blive en del af vores daglige liv. Inden for produktionsindustrien har det allerede være tilfældet i mange år, men anvendelsen af mobile robotter har hidtil været henvist til isolerede områder som græsslåning, overvågning, landbrugsproduktion og militære funktioner. Fremskridt i forskningen gør, at robotter vil kunne assistere os i mange af vore daglige gøremål i en ikke så fjern fremtid. En af de teknologier, der skal gøre dette muligt, er navigation, og navigation er e...

  18. Self-navigating robot

    Science.gov (United States)

    Thompson, A. M.

    1978-01-01

    Rangefinding equipment and onboard navigation system determine best route from point to point. Research robot has two TV cameras and laser for scanning and mapping its environment. Path planner finds most direct, unobstructed route that requires minimum expenditure of energy. Distance is used as measure of energy expense, although other measures such as time or power consumption (which would depend on the topography of the path) may be used.

  19. Navigating stories in films

    OpenAIRE

    Salway, Andrew; Xu, Yan

    2005-01-01

    This report describes the transformation of feature films into hypervideo by representing their story structures using plot unties. Plot units represent cause-effect relationships between characters’ affect states and the events in a story. We use plot units to structure hypervideo links between intervals of video data. We have manually analysed two full-length feature films in terms of plot units. A system was developed to store and edit data about plot units and to navigate films by followi...

  20. Invisible Navigation (or Impossible?).

    OpenAIRE

    Özcan, Oğuzhan; O'Neil, Mary Lou

    2013-01-01

    Abstract: This article introduces an experimental artwork on moving mobile interfaces. It aims to answer the question: Is it possible to navigate a part of a large image composition, moving a smaller interface of a mobile device in a certain direction such as left and right, back and forth or up and down? The article then outlines the new concept of “Invisible (or impossible) Navigation” and discusses the output of artistic practices which address the “Labyrinth of Art”.

  1. Navigational Query Languages

    OpenAIRE

    Surinx, Dimitri

    2013-01-01

    In this thesis we introduce navigational query languages on graphs. Path queries in our languages are built over several operators: identity, union, composition, projection, coprojection, converse, transitive closure, diversity, intersection and difference. The smallest language we will consider only contains the first 3 operators, while the largest language contains all operators. For these query languages we will characterize their complete relative expressive power, i.e., we will compare t...

  2. 19 CFR 4.61 - Requirements for clearance.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Requirements for clearance. 4.61 Section 4.61 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY VESSELS IN FOREIGN AND DOMESTIC TRADES Foreign Clearances § 4.61 Requirements for clearance. (a) Application for clearance. A...

  3. 48 CFR 801.602-76 - Business clearance review.

    Science.gov (United States)

    2010-10-01

    ... obtain a business clearance review prior to award of any contract, task or delivery order, or blanket... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Business clearance review... Authority, and Responsibilities 801.602-76 Business clearance review. (a) A business clearance review is...

  4. Multisensor robot navigation system

    Science.gov (United States)

    Persa, Stelian; Jonker, Pieter P.

    2002-02-01

    Almost all robot navigation systems work indoors. Outdoor robot navigation systems offer the potential for new application areas. The biggest single obstacle to building effective robot navigation systems is the lack of accurate wide-area sensors for trackers that report the locations and orientations of objects in an environment. Active (sensor-emitter) tracking technologies require powered-device installation, limiting their use to prepared areas that are relative free of natural or man-made interference sources. The hybrid tracker combines rate gyros and accelerometers with compass and tilt orientation sensor and DGPS system. Sensor distortions, delays and drift required compensation to achieve good results. The measurements from sensors are fused together to compensate for each other's limitations. Analysis and experimental results demonstrate the system effectiveness. The paper presents a field experiment for a low-cost strapdown-IMU (Inertial Measurement Unit)/DGPS combination, with data processing for the determination of 2-D components of position (trajectory), velocity and heading. In the present approach we have neglected earth rotation and gravity variations, because of the poor gyroscope sensitivities of our low-cost ISA (Inertial Sensor Assembly) and because of the relatively small area of the trajectory. The scope of this experiment was to test the feasibility of an integrated DGPS/IMU system of this type and to develop a field evaluation procedure for such a combination.

  5. Navigation in virtual environments

    Science.gov (United States)

    Arthur, Erik; Hancock, Peter A.; Telke, Susan

    1996-06-01

    Virtual environments show great promise in the area of training. ALthough such synthetic environments project homeomorphic physical representations of real- world layouts, it is not known how individuals develop models to match such environments. To evaluate this process, the present experiment examined the accuracy of triadic representations of objects having learned them previously under different conditions. The layout consisted of four different colored spheres arranged on a flat plane. These objects could be viewed in either a free navigation virtual environment condition (NAV) or a single body position virtual environment condition. The first condition allowed active exploration of the environment while the latter condition allowed the participant only a passive opportunity to observe form a single viewpoint. These viewing conditions were a between-subject variable with ten participants randomly assigned to each condition. Performance was assessed by the response latency to judge the accuracy of a layout of three objects over different rotations. Results showed linear increases in response latency as the rotation angle increased from the initial perspective in SBP condition. The NAV condition did not show a similar effect of rotation angle. These results suggest that the spatial knowledge acquisition from virtual environments through navigation is similar to actual navigation.

  6. Integrated navigation method based on inertial navigation system and Lidar

    Science.gov (United States)

    Zhang, Xiaoyue; Shi, Haitao; Pan, Jianye; Zhang, Chunxi

    2016-04-01

    An integrated navigation method based on the inertial navigational system (INS) and Lidar was proposed for land navigation. Compared with the traditional integrated navigational method and dead reckoning (DR) method, the influence of the inertial measurement unit (IMU) scale factor and misalignment was considered in the new method. First, the influence of the IMU scale factor and misalignment on navigation accuracy was analyzed. Based on the analysis, the integrated system error model of INS and Lidar was established, in which the IMU scale factor and misalignment error states were included. Then the observability of IMU error states was analyzed. According to the results of the observability analysis, the integrated system was optimized. Finally, numerical simulation and a vehicle test were carried out to validate the availability and utility of the proposed INS/Lidar integrated navigational method. Compared with the test result of a traditional integrated navigation method and DR method, the proposed integrated navigational method could result in a higher navigation precision. Consequently, the IMU scale factor and misalignment error were effectively compensated by the proposed method and the new integrated navigational method is valid.

  7. 75 FR 25037 - Lead; Clearance and Clearance Testing Requirements for the Renovation, Repair, and Painting Program

    Science.gov (United States)

    2010-05-06

    ... Protection Agency 40 CFR Part 745 Lead; Clearance and Clearance Testing Requirements for the Renovation..., 2010 / Proposed Rules#0;#0; ] ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 745 RIN 2070-AJ57 Lead... 2008 Lead Renovation, Repair, and Painting Program (RRP) rule that established accreditation,...

  8. 75 FR 38959 - Lead; Clearance and Clearance Testing Requirements for the Renovation, Repair, and Painting...

    Science.gov (United States)

    2010-07-07

    ... established in the Federal Register of May 6, 2010 (75 FR 25038) (FRL-8823-5). In that document, EPA proposed... AGENCY 40 CFR Part 745 RIN 2070-AJ57 Lead; Clearance and Clearance Testing Requirements for the... Federal Register of May 6, 2010, concerning several revisions to the 2008 Lead Renovation, Repair,...

  9. 33 CFR 401.53 - Obstructing navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Obstructing navigation. 401.53 Section 401.53 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Seaway Navigation § 401.53...

  10. Control algorithms for autonomous robot navigation

    International Nuclear Information System (INIS)

    This paper examines control algorithm requirements for autonomous robot navigation outside laboratory environments. Three aspects of navigation are considered: navigation control in explored terrain, environment interactions with robot sensors, and navigation control in unanticipated situations. Major navigation methods are presented and relevance of traditional human learning theory is discussed. A new navigation technique linking graph theory and incidental learning is introduced

  11. Control algorithms for autonomous robot navigation

    Energy Technology Data Exchange (ETDEWEB)

    Jorgensen, C.C.

    1985-09-20

    This paper examines control algorithm requirements for autonomous robot navigation outside laboratory environments. Three aspects of navigation are considered: navigation control in explored terrain, environment interactions with robot sensors, and navigation control in unanticipated situations. Major navigation methods are presented and relevance of traditional human learning theory is discussed. A new navigation technique linking graph theory and incidental learning is introduced.

  12. Understanding satellite navigation

    CERN Document Server

    Acharya, Rajat

    2014-01-01

    This book explains the basic principles of satellite navigation technology with the bare minimum of mathematics and without complex equations. It helps you to conceptualize the underlying theory from first principles, building up your knowledge gradually using practical demonstrations and worked examples. A full range of MATLAB simulations is used to visualize concepts and solve problems, allowing you to see what happens to signals and systems with different configurations. Implementation and applications are discussed, along with some special topics such as Kalman Filter and Ionosphere. W

  13. Navigating Hypermasculine Terrains

    DEFF Research Database (Denmark)

    Henriksen, Ann-Karina Eske

    2015-01-01

    The study addresses how young women navigate urban terrains that are characterized by high levels of interpersonal aggression and crime. It is argued that young women apply a range of gendered tactics to establish safety and social mastery, and that these are framed by the limits and possibilities...... imposed by a street-based hypermasculine script. The analysis rests on an ethnographic study among 25 young Danish women aged 13 to 23 experienced in engaging in street-based physical violence. The study suggests that explorations of female tactics can provide a useful method of analysis for understanding...

  14. China Satellite Navigation Conference

    CERN Document Server

    Liu, Jingnan; Fan, Shiwei; Wang, Feixue

    2016-01-01

    These Proceedings present selected research papers from CSNC2016, held during 18th-20th May in Changsha, China. The theme of CSNC2016 is Smart Sensing, Smart Perception. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC2016, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.

  15. A linguistic and navigational knowledge approach to text navigation

    OpenAIRE

    Couto, Javier; Minel, Jean-Luc

    2008-01-01

    We present an approach to text navigation conceived as a cognitive process exploiting linguistic information present in texts. We claim that the navigational knowledge in-volved in this process can be modeled in a declarative way with the Sextant language. Since Sextant refers exhaustively to specific linguistic phenomena, we have defined a customized text representation. These dif-ferent components are implemented in the text navigation system NaviTexte. Two ap-plications of NaviTexte are de...

  16. Learning for Autonomous Navigation

    Science.gov (United States)

    Angelova, Anelia; Howard, Andrew; Matthies, Larry; Tang, Benyang; Turmon, Michael; Mjolsness, Eric

    2005-01-01

    Robotic ground vehicles for outdoor applications have achieved some remarkable successes, notably in autonomous highway following (Dickmanns, 1987), planetary exploration (1), and off-road navigation on Earth (1). Nevertheless, major challenges remain to enable reliable, high-speed, autonomous navigation in a wide variety of complex, off-road terrain. 3-D perception of terrain geometry with imaging range sensors is the mainstay of off-road driving systems. However, the stopping distance at high speed exceeds the effective lookahead distance of existing range sensors. Prospects for extending the range of 3-D sensors is strongly limited by sensor physics, eye safety of lasers, and related issues. Range sensor limitations also allow vehicles to enter large cul-de-sacs even at low speed, leading to long detours. Moreover, sensing only terrain geometry fails to reveal mechanical properties of terrain that are critical to assessing its traversability, such as potential for slippage, sinkage, and the degree of compliance of potential obstacles. Rovers in the Mars Exploration Rover (MER) mission have got stuck in sand dunes and experienced significant downhill slippage in the vicinity of large rock hazards. Earth-based off-road robots today have very limited ability to discriminate traversable vegetation from non-traversable vegetation or rough ground. It is impossible today to preprogram a system with knowledge of these properties for all types of terrain and weather conditions that might be encountered.

  17. Clearance Laboratory - Capability and measurement sensitivity

    International Nuclear Information System (INIS)

    A new low-level Clearance Laboratory has been built at the Risoe-site. Building materials with a low content of naturally occurring radionuclides have been used. To minimize transport of radon gas from soil into the laboratory the foundation has been supplied with a membrane. The laboratory has been equipped with two high-efficiency germanium detectors. These detectors will be used for clearance measurements on the predicted amount of 15,000 - 18,000 tonnes of non-active or nearly non-active materials, which will originate from the decommissioning of all the nuclear facilities at the Risoe-site. They will be used also for clearance measurements on buildings and land. Objects and materials to be measured for clearance are placed on a rotation table that can carry up to one tonne and can rotate once a minute to simulate some averaging of inhomogeneously distributed activity. Sensitivity and background measurements reveal that measuring times of 20 - 50 minutes would normally be sufficient to detect radionuclide concentrations of only a small fraction of the nuclide-specific clearance levels with a sufficiently low uncertainty. Probability calculations of the measurement capacity of the Clearance Laboratory indicate that the mean value of the total measuring time for all materials that potentially can be cleared would be 13 years with a 95% probability of being less than 25 years. The mean value of the annual amount of materials that can be measured in the laboratory is 600 tonnes with a 95% probability of being less than 1,200 tonnes. If needed, there is room for additional measuring systems to increase the capacity of the laboratory. (au)

  18. Mucociliary clearance from the calf lung.

    OpenAIRE

    C.D. Jones

    1983-01-01

    Mucociliary clearance rate constants for ten calves were obtained using Technetium 99m-sulphur colloid complex. The mean rate constant measured at the lung for all calves was 0.012 (+/- 0.009) min-1 (half-life 58 minutes). The clearance rate constants obtained from measurements made at the larynx were higher (0.02 +/- 0.007 min-1), although not significantly higher, than those determined from measurements taken at the lung. The constants can be used to predict the particle burden on the lungs...

  19. Effects of airborne pollutants on mucociliary clearance.

    OpenAIRE

    Wolff, R K

    1986-01-01

    The mucociliary clearance system is a first line of defense against inhaled agents, and so its compromise can adversely affect health. The purpose of this paper is to provide a review of data on the effect of in vivo air pollutant exposures on the clearance of test particles from airways. Data from both animals and humans are compared whenever possible, so that estimates of human health effects may be made. Mechanisms of action are also discussed, presenting the view that for low level exposu...

  20. Nasal mucociliary clearance in patients with tracheostomy

    OpenAIRE

    Yadav, S. P. S.; Janab, Khan Shariq; Singh, Jagat; Ranga, Rupender K.

    2003-01-01

    Nasal mucociliary clearance (NMC) time was estimated in 30 tracheostomized patients (24 males & 6 females) in the age group of 13–55 years which was 7.04±0.38 minutes: The patients suffering from nose and paranasal sinus disorders; taking drugs like bromhexine; undergoing radiotherapy and smokers were excluded from the study. The nasal mucociliary clearance in 30 age & sex matched healthy controls was 9.16±0.62 minutes. The NMC was found to he significantly lowered in patients with tracheosto...

  1. Impact of Glycation on Antibody Clearance

    OpenAIRE

    Yang, Jane; Primack, Ronya; Frohn, Mike; Wang, Wei; Luan, Peng; Retter, Marc W.; Flynn, Gregory C.

    2014-01-01

    Glycation of therapeutic proteins occurs during mammalian cell culture expression and upon administration to patients. Since the chemical attachment of mannose or other sugars via a chemical linker has been shown to increase a protein’s clearance rate in mice through the mannose receptor, we explored the effect of mannose glycation on the clearance of an IgG in mice. An IgG decorated with high levels of mannose (~18 mol/mol protein) through glycation did not clear faster in mice than the unde...

  2. Glycerol clearance in alcoholic liver disease.

    OpenAIRE

    Johnston, D G; Alberti, K. G.; Wright, R; Blain, P G

    1982-01-01

    Glycerol clearance was studied by a primed dose-constant infusion technique in 14 patients with alcoholic liver disease and six normal control subjects. Fasting blood glycerol concentrations were raised in the alcoholic subjects (0.09 +/- 0.01 vs 0.06 +/- 0.01 mumol/l, p less than 0.05) and glycerol clearance was impaired (24.5 +/- 1.9 vs 37.5 +/- 3.2 ml/kg/min, p less than 0.005). Endogenous production rate of glycerol and distribution space at steady state were similar in alcoholic and cont...

  3. Pharmacologic agents for mucus clearance in bronchiectasis.

    Science.gov (United States)

    Nair, Girish B; Ilowite, Jonathan S

    2012-06-01

    There are no approved pharmacologic agents to enhance mucus clearance in non-cystic fibrosis (CF) bronchiectasis. Evidence supports the use of hyperosmolar agents in CF, and studies with inhaled mannitol and hypertonic saline are ongoing in bronchiectasis. N-acetylcysteine may act more as an antioxidant than a mucolytic in other lung diseases. Dornase α is beneficial to patients with CF, but is not useful in patients with non-CF bronchiectasis. Mucokinetic agents such as β-agonists have the potential to improve mucociliary clearance in normals and many disease states, but have not been adequately studied in patients with bronchiectasis. PMID:22640851

  4. 33 CFR 207.185 - Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Taylors Bayou, Tex., Beaumont Navigation District Lock; use, administration, and navigation. 207.185 Section 207.185 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION...

  5. 32 CFR 154.16 - Security clearance.

    Science.gov (United States)

    2010-07-01

    ..., such as guards, emergency service personnel, firemen, doctors, nurses, police, ambulance drivers, or... shall be accomplished in accordance with 32 CFR part 159. The investigative requirement shall be the... be processed for a security clearance in accordance with 32 CFR part 353 and the provisions of...

  6. Uptake and clearance of uranium by misgurnus

    International Nuclear Information System (INIS)

    The author studied the bioconcentration and clearance of uranium in misgurnus and determined bioconcentration factors (BCF) as well as uptake and depuration rate constants. The test was performed under semi-static conditions. The depuration of uranium was best described by a two-compartment first order kinetic model

  7. Clearance of seborrhoeic keratoses with topical dobesilate

    OpenAIRE

    Cuevas, Pedro; Angulo, Javier; Salgüero, Irene; Giménez-Gallego, Guillermo

    2012-01-01

    A patient with two seborrhoeic keratoses in the face received a single daily application of dobesilate cream during 6 months. Dobesilate achieved complete clearance of the seborrhoeic keratosis lesions with good cosmoses, suggesting that this compound is a safe and efficient candidate in the treatment of seborrhoeic keratoses.

  8. 30 CFR 57.11008 - Restricted clearance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Restricted clearance. 57.11008 Section 57.11008 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Travelways and Escapeways Travelways-Surface and Underground §...

  9. 30 CFR 57.7018 - Hand clearance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand clearance. 57.7018 Section 57.7018 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Drilling-Surface Only § 57.7018...

  10. 30 CFR 57.7028 - Hand clearance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand clearance. 57.7028 Section 57.7028 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Drilling-Underground Only § 57.7028...

  11. 30 CFR 57.11010 - Stairstep clearance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Stairstep clearance. 57.11010 Section 57.11010 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Travelways and Escapeways Travelways-Surface and Underground...

  12. Clearance measurements on a hot cell building

    International Nuclear Information System (INIS)

    A former hot-cell facility of Siemens AG, in which dose rates in excess of 99 Sv were still prevailing in 1999, was decontaminated and subjected, except for the basement, to radiological clearance measurements. The authorities released the building for demolition in November 2004. Demolition of the upper stories of the building was started immediately afterwards using conventional techniques. For decontamination, the actual cells themselves - rooms with one-meter-thick concrete walls - had been dismantled using diamond saws and the resulting concrete blocks sent off-site for further processing. Contamination was removed from the remaining ceilings, walls and floors by knocking off the plaster and milling away the screed. Material samples were taken to confirm that decontamination had been successful. It was only then that the actual clearance measurements began. The individual rooms were grouped together into logically arranged ''clearance steps'' to simplify documentation. Most of the measurements were performed by in-situ gamma spectroscopy, with and without collimation. In addition, numerous material specimens were removed, direct surface measurements performed using contamination monitors, and wipe tests carried out. Records were made of all measurements and sorted according to clearance steps before being submitted to the competent authorities as an application for release from regulatory control. After the authorities had taken their own verification measurements they issued their approval for release. (orig.)

  13. Ground Taxi Navigation Problems and Training Solutions

    Science.gov (United States)

    Quinn, Cheryl; Walter, Kim E.; Rosekind, Mark (Technical Monitor)

    1997-01-01

    Adverse weather conditions can put considerable strain on the National Airspace System. Even small decreases in visibility on the airport surface can create delays, hinder safe movement and lead to errors. Studies of Aviation Safety Reporting System (ASRS) surface movement incidents support the need for technologies and procedures to improve ground operations in low-visibility conditions. This study examined 139 ASRS reports of low-visibility surface movement incidents at 10 major U.S. airports. Errors were characterized in terms of incident type, contributing factors and consequences. The incidents in the present sample were comprised of runway transgressions, taxiway excursions and ground conflicts. The primary contributing factors were Airport Layout and Markings, Communication and Distraction. In half the incidents the controller issued a new clearance or the flight crew took an evasive action and in the remaining half, no recovery attempt was made because the error was detected after the fact. By gaining a better understanding the factors that affect crew navigation in low visibility and the types of errors that are likely to occur, it will be possible to develop more robust technologies to aid pilots in the ground taxi task. Implications for crew training and procedure development for low-visibility ground taxi are also discussed.

  14. Tracheobronchial clearance studies in the guinea pig

    International Nuclear Information System (INIS)

    Tracheobronchial clearance in guinea pigs exposed to relatively monodisperse aerosols was studied. Two new techniques were developed which enabled tagging of polystyrene particles with 198Au and with a fluorescent dye. A procedure was also developed to generate polystyrene particles with a vibrating orifice generator. Seventy animals were exposed via inhalation to relatively monodisperse polystyrene aerosols. Following exposure, animals were radioactively counted at regular intervals, sacrificed at predetermined times, and the lungs were removed, inflated to a standard pressure, frozen in liquid nitrogen, and freeze-dried. The freeze-dried lungs were sectioned completely, examined with a fluorescent microscope, and measurements were made of airway diameters in which particles were found. The results indicated a significant penetration of particles to the distal bronchioles and air spaces for 7.9 μm (MMD) particles and a lesser, though still significant, penetration for 10.3 μm (MMD) particles. An anatomical model for guinea pig lung morphology was used to classify particular ranges of airway diameters into zones. These zones were used to specify a compartmental model for lung clearance and the experimental particle distributions were categorized using this model. Equations were then developed describing the compartmental clearance. Rate constants were then obtained and used to predict airway transport rates in specific lung generations.The predicted transport rates ranged from approximately 0.001 mm/min in the distal bronchioles to approximately 8 mm/min in the trachea. These values agree with previous models for airway transport rates, and are consistent with experimental determinations of tracheal transport rates. Transit times were calculated and the results indicate a 24 hr clearance time for tracheobronchial clearance in the guinea pig

  15. 19 CFR 122.26 - Entry and clearance.

    Science.gov (United States)

    2010-04-01

    ... AIR COMMERCE REGULATIONS Private Aircraft § 122.26 Entry and clearance. Private aircraft, as defined... information as set forth in § 122.22(c), and grants electronic clearance via electronic mail or telephone....

  16. Introductory Course on Satellite Navigation

    Science.gov (United States)

    Giger, Kaspar; Knogl, J. Sebastian

    2012-01-01

    Satellite navigation is widely used for personal navigation and more and more in precise and safety-critical applications. Thus, the subject is suited for attracting the interest of young people in science and engineering. The practical applications allow catching the students' attention for the theoretical background. Educational material on the…

  17. Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator

    OpenAIRE

    Flegg Jennifer A; Guerin Philippe J; White Nicholas J; Stepniewska Kasia

    2011-01-01

    Abstract Background A significant reduction in parasite clearance rates following artesunate treatment of falciparum malaria, and increased failure rates following artemisinin combination treatments (ACT), signaled emergent artemisinin resistance in Western Cambodia. Accurate measurement of parasite clearance is therefore essential to assess the spread of artemisinin resistance in Plasmodium falciparum. The slope of the log-parasitaemia versus time relationship is considered to be the most ro...

  18. Autonomous Spacecraft Navigation With Pulsars

    CERN Document Server

    Becker, Werner; Jessner, Axel

    2013-01-01

    An external reference system suitable for deep space navigation can be defined by fast spinning and strongly magnetized neutron stars, called pulsars. Their beamed periodic signals have timing stabilities comparable to atomic clocks and provide characteristic temporal signatures that can be used as natural navigation beacons, quite similar to the use of GPS satellites for navigation on Earth. By comparing pulse arrival times measured on-board a spacecraft with predicted pulse arrivals at a reference location, the spacecraft position can be determined autonomously and with high accuracy everywhere in the solar system and beyond. The unique properties of pulsars make clear already today that such a navigation system will have its application in future astronautics. In this paper we describe the basic principle of spacecraft navigation using pulsars and report on the current development status of this novel technology.

  19. Effect of inhibitors of prostaglandin synthesis on hepatic drug clearance.

    OpenAIRE

    Feely, J; Wood, A. J.

    1983-01-01

    The effect of inhibition of prostaglandin synthesis on the systemic clearance of indocyanine green and antipyrine was studied in seven subjects. Antipyrine clearance was not altered by indomethacin suggesting that oxidative metabolism was not affected. Both aspirin and indomethacin decreased the clearance of indocyanine green presumably by reducing liver blood flow. These results suggest that an effect of inhibitors of prostaglandin synthesis on hepatic drug clearance is likely to be confined...

  20. Diminished creatinine clearance in anorexia nervosa: reversal with weight gain.

    OpenAIRE

    Boag, F.; Weerakoon, J; Ginsburg, J; Havard, C W; Dandona, P

    1985-01-01

    To assess whether patients with anorexia nervosa have abnormalities in creatinine clearance, we measured plasma creatinine concentration, urinary creatinine excretion, and creatinine clearance in 10 patients with anorexia nervosa before and during treatment. Urinary creatinine excretion and creatinine clearance were diminished in all patients. Nine patients had significant decreases in their plasma creatinine and creatinine clearance was increased even when corrected for body weight and body ...

  1. The clearance of albumin microspheres from an intramuscular injection site

    International Nuclear Information System (INIS)

    Human serum albumin microspheres of three different diameters were radiolabelled with indium-111, and a suspension injected into rabbit thigh muscle. Clearance from the intramuscular site was monitored for 2 weeks using gamma scintigraphy. The clearance rates were compared with the injection site clearance of non-biodegradable polystyrene microspheres. (U.K.)

  2. 14 CFR 27.661 - Rotor blade clearance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Rotor blade clearance. 27.661 Section 27... AIRWORTHINESS STANDARDS: NORMAL CATEGORY ROTORCRAFT Design and Construction Rotors § 27.661 Rotor blade clearance. There must be enough clearance between the rotor blades and other parts of the structure...

  3. 14 CFR 29.661 - Rotor blade clearance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Rotor blade clearance. 29.661 Section 29... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY ROTORCRAFT Design and Construction Rotors § 29.661 Rotor blade clearance. There must be enough clearance between the rotor blades and other parts of the structure...

  4. 49 CFR Appendix F to Part 512 - OMB Clearance

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false OMB Clearance F Appendix F to Part 512 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONFIDENTIAL BUSINESS INFORMATION Pt. 512, App. F Appendix F to Part 512—OMB Clearance The OMB clearance...

  5. 46 CFR 56.75-10 - Joint clearance.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Joint clearance. 56.75-10 Section 56.75-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PIPING SYSTEMS AND APPURTENANCES Brazing § 56.75-10 Joint clearance. (a) The clearance between surfaces to be joined shall be no larger than is necessary to insure...

  6. Wear analysis of revolute joints with clearance in multibody systems

    Science.gov (United States)

    Bai, ZhengFeng; Zhao, Yang; Wang, XingGui

    2013-08-01

    In this work, the prediction of wear for revolute joint with clearance in multibody systems is investigated using a computational methodology. The contact model in clearance joint is established using a new hybrid nonlinear contact force model and the friction effect is considered by using a modified Coulomb friction model. The dynamics model of multibody system with clearance is established using dynamic segmentation modeling method and the computational process for wear analysis of clearance joint in multibody systems is presented. The main computational process for wear analysis of clearance joint includes two steps, which are dynamics analysis and wear analysis. The dynamics simulation of multibody system with revolute clearance joint is carried out and the contact forces are drawn and used to calculate the wear amount of revolute clearance joint based on the Archard's wear model. Finally, a four-bar multibody mechanical system with revolute clearance joint is used as numerical example application to perform the simulation and show the dynamics responses and wear characteristics of multibody systems with revolute clearance joint. The main results of this work indicate that the contact between the joint elements is wider and more frequent in some specific regions and the wear phenomenon is not regular around the joint surface, which causes the clearance size increase non-regularly after clearance joint wear. This work presents an effective method to predict wear of revolute joint with clearance in multibody systems.

  7. Guangzhou Customs Guide to Clearance of Import/Export Goods

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Management of the Enterprises Granted for Convenient and Quick Customs Clearance 1.What is the enterprise granted for convenient and quick customs clearance? Customs General Administration and the Ministry of Foreign Trade and Economic Cooperation jointly issued policy measures to facilitate customs clearance in 2001 to further support the development of hightech industries.The enterprise .

  8. 14 CFR 1260.63 - Customs clearance and visas.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Customs clearance and visas. 1260.63 Section 1260.63 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General Special Conditions § 1260.63 Customs clearance and visas. Customs Clearance and Visas...

  9. Lunar Navigation Architecture Design Considerations

    Science.gov (United States)

    D'Souza, Christopher; Getchius, Joel; Holt, Greg; Moreau, Michael

    2009-01-01

    The NASA Constellation Program is aiming to establish a long-term presence on the lunar surface. The Constellation elements (Orion, Altair, Earth Departure Stage, and Ares launch vehicles) will require a lunar navigation architecture for navigation state updates during lunar-class missions. Orion in particular has baselined earth-based ground direct tracking as the primary source for much of its absolute navigation needs. However, due to the uncertainty in the lunar navigation architecture, the Orion program has had to make certain assumptions on the capabilities of such architectures in order to adequately scale the vehicle design trade space. The following paper outlines lunar navigation requirements, the Orion program assumptions, and the impacts of these assumptions to the lunar navigation architecture design. The selection of potential sites was based upon geometric baselines, logistical feasibility, redundancy, and abort support capability. Simulated navigation covariances mapped to entry interface flightpath- angle uncertainties were used to evaluate knowledge errors. A minimum ground station architecture was identified consisting of Goldstone, Madrid, Canberra, Santiago, Hartebeeshoek, Dongora, Hawaii, Guam, and Ascension Island (or the geometric equivalent).

  10. Navigable networks as Nash equilibria of navigation games

    Science.gov (United States)

    Gulyás, András; Bíró, József J.; Kőrösi, Attila; Rétvári, Gábor; Krioukov, Dmitri

    2015-07-01

    Common sense suggests that networks are not random mazes of purposeless connections, but that these connections are organized so that networks can perform their functions well. One function common to many networks is targeted transport or navigation. Here, using game theory, we show that minimalistic networks designed to maximize the navigation efficiency at minimal cost share basic structural properties with real networks. These idealistic networks are Nash equilibria of a network construction game whose purpose is to find an optimal trade-off between the network cost and navigability. We show that these skeletons are present in the Internet, metabolic, English word, US airport, Hungarian road networks, and in a structural network of the human brain. The knowledge of these skeletons allows one to identify the minimal number of edges, by altering which one can efficiently improve or paralyse navigation in the network.

  11. A greedy-navigator approach to navigable city plans

    CERN Document Server

    Lee, Sang Hoon

    2012-01-01

    We use a set of four theoretical navigability indices for street maps to investigate the shape of the resulting street networks, if they are grown by optimizing these indices. The indices compare the performance of simulated navigators (having a partial information about the surroundings, like humans in many real situations) to the performance of optimally navigating individuals. We show that our simple greedy shortcut construction strategy generates the emerging structures that are different from real road network, but not inconceivable. The resulting city plans, for all navigation indices, share common qualitative properties such as the tendency for triangular blocks to appear, while the more quantitative features, such as degree distributions and clustering, are characteristically different depending on the type of metrics and routing strategies. We show that it is the type of metrics used which determines the overall shapes characterized by structural heterogeneity, but the routing schemes contribute to m...

  12. Nasal mucociliary clearance in coal mine workers

    Energy Technology Data Exchange (ETDEWEB)

    Cinar, F.; Beder, L. [Karaelmas University, Kozlu Zonguldak (Turkey)

    2004-06-01

    The purpose of this study was to analyze the effect of coal dust particles on nasal mucociliary function in coal mine workers. Using the saccharin method, nasal mucociliary clearance was determined for 77 subjects, of which 39 who worked in a coal mine were actively exposed to coal dust whereas 38 were unexposed control subjects. The measurements were performed in the coal mine, at the level of 170 m below sea level. The average saccharin nasal transit time in coal mine workers, 12.61 (SD: 4.30) minutes, is longer, than that of the control subjects, 10.97 (SD: 3.22). Although the findings of this study demonstrate that the coal particles affect the nasal mucociliary clearance, the difference in saccharin nasal transit time between the two groups (exposed vs unexposed) is not statistically significant (P = 0.063).

  13. Navigation/Prop Software Suite

    Science.gov (United States)

    Bruchmiller, Tomas; Tran, Sanh; Lee, Mathew; Bucker, Scott; Bupane, Catherine; Bennett, Charles; Cantu, Sergio; Kwong, Ping; Propst, Carolyn

    2012-01-01

    Navigation (Nav)/Prop software is used to support shuttle mission analysis, production, and some operations tasks. The Nav/Prop suite containing configuration items (CIs) resides on IPS/Linux workstations. It features lifecycle documents, and data files used for shuttle navigation and propellant analysis for all flight segments. This suite also includes trajectory server, archive server, and RAT software residing on MCC/Linux workstations. Navigation/Prop represents tool versions established during or after IPS Equipment Rehost-3 or after the MCC Rehost.

  14. Discovery of Individual User Navigation Styles

    OpenAIRE

    Herder, E.; Juvina, I.

    2004-01-01

    Individual differences have been shown to lead to different navigation styles. In this paper we present a pilot study that aims at finding predictors for users’ vulnerability to experience disorientation that can be gathered unobtrusively and in real-time. We identified two navigation styles that we called flimsy navigation and laborious navigation that together predict users’ perceived disorientation. Our findings suggest that adaptive navigation support that addresses these navigation style...

  15. Pulmonary clearance of vasoactive intestinal peptide.

    OpenAIRE

    Barrowcliffe, M P; Morice, A; Jones, J G; Sever, P S

    1986-01-01

    Vasoactive intestinal peptide causes bronchodilatation when given intravenously but is less effective in both animals and man when given by inhalation. This difference may be due to poor transit of the peptide across the bronchial epithelium. To test this hypothesis pulmonary clearance of radiolabelled vasoactive intestinal peptide was measured in Sprague Dawley rats and compared with that of pertechnetate (TcO4-) and diethylene triamine pentaacetate (DTPA). Despite a molecular weight (MW) of...

  16. Bomb strike experiment for mine clearance operations

    OpenAIRE

    Ray, Gregory P.

    2006-01-01

    The Bomb Strike Experiment for Mine Countermeasure Operations, currently sponsored through the Office of Naval Research mine impact burial prediction project, is part of a multi-year, comprehensive effort aimed at enhancing the Navyâ s fleet naval mine clearance capability and success. The investigation discussed in this paper examines the experimental and theoretical characteristics of a rigid body falling through the air, water, and sediment column at high speed. Several experiments were ...

  17. Stereoselective renal clearance of pindolol in humans.

    OpenAIRE

    Hsyu, P H; Giacomini, K M

    1985-01-01

    In this study, pindolol, a beta-adrenoceptor blocking agent marketed as a racemic mixture, was used as a model compound to investigate stereoselective renal clearance of organic cations in human beings. Six normal subjects received an oral dose of 20 mg racemic pindolol. Heart rate and blood pressure were measured throughout the study. A stereospecific high performance liquid chromatographic procedure was used to quantitate the concentrations of d- and l-pindolol in plasma and urine. Renal cl...

  18. Antipyrine clearance during occupational exposure to styrene.

    OpenAIRE

    Døssing, M

    1983-01-01

    Animal experiments have indicated that styrene, which is a widely used organic solvent, may induce the microsomal enzyme function of the liver. Thirteen workers with long-term exposure to styrene in a polyester plant were investigated. They worked at air concentrations about the maximal allowed time-weighted average concentration of styrene in most Western countries (50 ppm). The clearance of antipyrine was determined from saliva concentrations before and after three weeks free of exposure an...

  19. Clearance of bronchial secretions after major surgery

    OpenAIRE

    Leur, Johannes Peter van de

    2005-01-01

    Minimally invasive airway suctioning is equally effective as routine endotracheal suctioning but results in less suction related adverse events, less recollection of suctioning and less stress. Thus, although it cannot be employed in all situations, minimally invasive airway suctioning should be the “default setting” for mucus clearance in ICU-patients. Special suction catheters should be marketed that do not pass the distal tip of the endotracheal tube. Alternatively, standard catheters can ...

  20. Promoter clearance by RNA polymerase II

    OpenAIRE

    Luse, Donal S.

    2012-01-01

    Many changes must occur to the RNA polymerase II (pol II) transcription complex as it makes the transition from initiation into transcript elongation. During this intermediate phase of transcription, contact with initiation factors is lost and stable association with the nascent transcript is established. These changes collectively comprise promoter clearance. Once the transcript elongation complex has reached a point where its properties are indistinguishable from those of complexes with muc...

  1. Hemodialysis clearance of intravenously administered ribavirin.

    OpenAIRE

    Kramer, T H; Gaar, G G; Ray, C G; Minnich, L; Copeland, J G; Connor, J. D.

    1990-01-01

    A patient with an implanted artificial heart, acute, anuric renal failure, and disseminated influenza virus type A infection received intravenous ribavirin. Drug elimination by hemodialysis was measured. Plasma dialysis clearance averaged 93.9 +/- 8.6 ml/min. The maximum amount of ribavirin removed from the body during one period of hemodialysis was 79.1 mg. Ribavirin is not removed in important quantities by hemodialysis.

  2. Immune clearance of highly pathogenic SIV infection

    OpenAIRE

    Hansen, Scott G.; Piatak, Michael; Ventura, Abigail B.; Hughes, Colette M.; Gilbride, Roxanne M.; Ford, Julia C.; Oswald, Kelli; Shoemaker, Rebecca; Li, Yuan; Matthew S. Lewis; Gilliam, Awbrey N.; Xu, Guangwu; Whizin, Nathan; Burwitz, Benjamin J; Planer, Shannon L.

    2013-01-01

    Established infections with the human and simian immunodeficiency viruses (HIV, SIV) are thought to be permanent with even the most effective immune responses and anti-retroviral therapies (ART) only able to control, but not clear, these infections 1–4 . Whether the residual virus that maintains these infections is vulnerable to clearance is a question of central importance to the future management of millions of HIV-infected individuals. We recently reported that ~50% of rhesus macaques (RM)...

  3. ADSORBENTS USED IN THE CLEARANCE OF ENDOTOXIN

    Institute of Scientific and Technical Information of China (English)

    YU Mei; LIU Tao; Hou Guanghui; YUAN Zhi

    2003-01-01

    A series of modified poly (methyl methacrylate, PMMA) resins were prepared and compared their adsorption abilities to endotoxin. The results showed that adsorbents, which were grafted with tertiary amine and long spacing arms, had the best adsorption capacities and good blood compatibility, It is hopeful to be used as adsorbent in hemoperfusion for clinical clearance of endotoxin. The influence of original concentration of endotoxin on adsorption and the adsorption mechanism were also investigated.

  4. Navigating "Assisted Dying".

    Science.gov (United States)

    Schipper, Harvey

    2016-02-01

    Carter is a bellwether decision, an adjudication on a narrow point of law whose implications are vast across society, and whose impact may not be realized for years. Coupled with Quebec's Act Respecting End-of-life Care it has sharply changed the legal landscape with respect to actively ending a person's life. "Medically assisted dying" will be permitted under circumstances, and through processes, which have yet to be operationally defined. This decision carries with it moral assumptions, which mean that it will be difficult to reach a unifying consensus. For some, the decision and Act reflect a modern acknowledgement of individual autonomy. For others, allowing such acts is morally unspeakable. Having opened the Pandora's Box, the question becomes one of navigating a tolerable societal path. I believe it is possible to achieve a workable solution based on the core principle that "medically assisted dying" should be a very rarely employed last option, subject to transparent ongoing review, specifically as to why it was deemed necessary. My analysis is based on 1. The societal conditions in which have fostered demand for "assisted dying", 2. Actions in other jurisdictions, 3. Carter and Quebec Bill 52, 4. Political considerations, 5. Current medical practice. Leading to a series of recommendations regarding. 1. Legislation and regulation, 2. The role of professional regulatory agencies, 3. Medical professions education and practice, 4. Public education, 5. Health care delivery and palliative care. Given the burden of public opinion, and the legal steps already taken, a process for assisted-dying is required. However, those legal and regulatory steps should only be considered a necessary and defensive first step in a two stage process. The larger goal, the second step, is to drive the improvement of care, and thus minimize assisted-dying. PMID:27169205

  5. Navigation System of Marks Areas - USACE IENC

    Data.gov (United States)

    Department of Homeland Security — These inland electronic Navigational charts (IENCs) were developed from available data used in maintenance of Navigation channels. Users of these IENCs should be...

  6. Establishing exemption and clearance criteria by the regulatory authority

    International Nuclear Information System (INIS)

    This Project work discusses the relationship between the concepts of exemption and clearance, and their practical use in the overall scheme of regulatory control of practices. It also discusses how exemptions and clearance is established and the scope of its applications for regulatory control. The concept of general clearance levels for any type of material and any possible pathway of disposal is also introduced in this work. Guidance of the Group of Experts establishing scenarios for general clearance, parameter values, and a nuclide-specific list of calculated clearance levels is also presented. Regulatory authorities are required to develop guidance on exemption and clearance levels to assist licensees and registrants to know which practices and sources within practices are exempted from regulatory control and those to be cleared from further controls. Exemption and clearance levels are tools for assisting the Regulatory Authority to optimize the use of resources. (author)

  7. Radio Navigation Waveform Experiment Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA is installing the Communications, Navigation, and Networking reConfigurable Testbed (CoNNeCT) onto the truss of the International Space Station to demonstrate...

  8. NOAA Electronic Navigational Charts (ENC)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Office of Coast Survey (OCS) has been involved in the development of a NOAA Electronic Navigational Chart (NOAA ENC) suite to support the marine transportation...

  9. FLASH LIDAR Based Relative Navigation

    Science.gov (United States)

    Brazzel, Jack; Clark, Fred; Milenkovic, Zoran

    2014-01-01

    Relative navigation remains the most challenging part of spacecraft rendezvous and docking. In recent years, flash LIDARs, have been increasingly selected as the go-to sensors for proximity operations and docking. Flash LIDARS are generally lighter and require less power that scanning Lidars. Flash LIDARs do not have moving parts, and they are capable of tracking multiple targets as well as generating a 3D map of a given target. However, there are some significant drawbacks of Flash Lidars that must be resolved if their use is to be of long-term significance. Overcoming the challenges of Flash LIDARs for navigation-namely, low technology readiness level, lack of historical performance data, target identification, existence of false positives, and performance of vision processing algorithms as intermediaries between the raw sensor data and the Kalman filter-requires a world-class testing facility, such as the Lockheed Martin Space Operations Simulation Center (SOSC). Ground-based testing is a critical step for maturing the next-generation flash LIDAR-based spacecraft relative navigation. This paper will focus on the tests of an integrated relative navigation system conducted at the SOSC in January 2014. The intent of the tests was to characterize and then improve the performance of relative navigation, while addressing many of the flash LIDAR challenges mentioned above. A section on navigation performance and future recommendation completes the discussion.

  10. Clearance and release from control - An international perspective

    International Nuclear Information System (INIS)

    This paper tries to give an overview of the clearance, or release from regulatory control, on an international scale, including some of those countries where clearance has become or is about to become vital for D and D. The emphasis lies on the impact of clearance, and in particular of differences between clearance levels of various countries, on D and D. Relevance of clearance for D and D of nuclear installations Clearance is an essential part of waste management (or more general, material management) in nuclear installations, and in particular during the decommissioning phase where waste streams continues to arise. Of course, the relevance of clearance in a particular country depends on a number of factors, like: availability of a final repository and its price; prevailing decommissioning strategy; number of nuclear installations reaching decommissioning phase. This small selection of reasons why clearance may be of varying importance for different countries may already suffice to illustrate why up to now clearance has been developed and implemented in quite different ways. If one thinks of additional reasons that may influence clearance, like politics, the public opinion, availability of funds etc., the situation becomes even more complex. It is, however safe to draw the conclusion that countries with a certain number of nuclear installations which have been or will soon be shut down or which are already in the decommissioning phase will need to implement provisions for clearance. This has indeed been the case with countries like the UK, Germany, the USA, Sweden, and a number of others. It is not essential for clearance levels to be exactly equal between various countries. They may differ as long as the difference is not too large, e.g. the values fall into the same order of magnitude. This is the reason why for example Germany has no problems with clearance levels which differ from the EU recommendation RP 122 partially adopted in a number of EU countries

  11. 33 CFR 66.10-15 - Aids to navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Aids to navigation. 66.10-15 Section 66.10-15 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION PRIVATE AIDS TO NAVIGATION Uniform State Waterway Marking System § 66.10-15 Aids to navigation....

  12. Modelling group navigation: transitive social structures improve navigational performance.

    Science.gov (United States)

    Flack, Andrea; Biro, Dora; Guilford, Tim; Freeman, Robin

    2015-07-01

    Collective navigation demands that group members reach consensus on which path to follow, a task that might become more challenging when the group's members have different social connections. Group decision-making mechanisms have been studied successfully in the past using individual-based modelling, although many of these studies have neglected the role of social connections between the group's interacting members. Nevertheless, empirical studies have demonstrated that individual recognition, previous shared experiences and inter-individual familiarity can influence the cohesion and the dynamics of the group as well as the relative spatial positions of specific individuals within it. Here, we use models of collective motion to study the impact of social relationships on group navigation by introducing social network structures into a model of collective motion. Our results show that groups consisting of equally informed individuals achieve the highest level of accuracy when they are hierarchically organized with the minimum number of preferred connections per individual. We also observe that the navigational accuracy of a group will depend strongly on detailed aspects of its social organization. More specifically, group navigation does not only depend on the underlying social relationships, but also on how much weight leading individuals put on following others. Also, we show that groups with certain social structures can compensate better for an increased level of navigational error. The results have broader implications for studies on collective navigation and motion because they show that only by considering a group's social system can we fully elucidate the dynamics and advantages of joint movements. PMID:26063820

  13. Investigations of renal clearance in nuclear medicine

    International Nuclear Information System (INIS)

    Comparative investigations of PAH- and inulin-clearance and results of investigations with J-131-hippurate and Cr-51-EDTA, which were performed by a partly screened whole body counter including measurements of activity retention of blood samples, are showing good correlation. If the radio-isotope nephrography is worked out together with the decreased retention curve, separate results of the function of both kidneys can be given. Modifications which were tried to analyze a small part of the retention curve instead of the whole body are inaccurate, if they are below 300 ml/min. (orig.)

  14. Carbamazepine Clearance and Seizure Stability during Pregnancy

    OpenAIRE

    Johnson, Emily L.; Stowe, Zachary N.; Ritchie, James C; Newport, D. Jeffrey; Newman, Melanee L.; Knight, Bettina; Pennell, Page B

    2014-01-01

    The aims of this study were to characterize the alterations in total and free carbamazepine (CBZ) and total and free carbamazepine-epoxide (CBZ-EPO) clearances during pregnancy; to calculate the change in free fractions of CBZ and CBZ-EPO during pregnancy; and to determine whether seizure worsening is associated with a low ratio to non-pregnant baseline concentration of total or free CBZ or CBZ-EPO. Women on CBZ were enrolled before conception or during pregnancy in this prospective, observat...

  15. Study of blade clearance effects on centrifugal pumps

    Science.gov (United States)

    Hoshide, R. K.; Nielson, C. E.

    1972-01-01

    A program of analysis, design, fabrication, and testing has been conducted to develop and experimentally verify analytical models to predict the effects of impeller blade clearance on centrifugal pumps. The effect of tip clearance on pump efficiency, and the relationship between the head coefficient and torque loss with tip clearance was established. Analysis were performed to determine the cost variation in design, manufacture, and test that would occur between unshrouded and shrouded impellers. An impeller, representative of typical rocket engine impellers, was modified by removing its front shroud to permit variation of its blade clearances. It was tested in water with special instrumentation to provide measurements of blade surface pressures during operation. Pump performance data were obtained from tests at various impeller tip clearances. Blade pressure data were obtained at the nominal tip clearance. Comparisons of predicted and measured data are given.

  16. Exploring requirements for indoor navigation systems

    OpenAIRE

    Ni, Chunxiao

    2013-01-01

    Indoor navigation has been a subject in ubiquitous computing domain in the past decade. Recently many studies focus on exploring user requirements for indoor navigation systems and make effort in developing effective interactive systems to support indoor navigation. This study aims to find which kind of spatial representation and what orientation cues common users prefer to use for indoor navigation. An experiment was performed to examine the navigation effectiveness and user satisfaction wit...

  17. EC and IAEA guidance on exemption and clearance levels and implications on clearance in Germany

    Energy Technology Data Exchange (ETDEWEB)

    Thierfeldt, S.; Woerlen, S.; Barthel, R. [Brenk Systemplanung GmbH, Aachen (Germany)

    2009-07-01

    The current EURATOM Basic Safety Standards (BSS), the Council Directive 96/29/EURATOM of 13 May 1996 [1], contain general provisions for clearance in Article 5 but no specific clearance levels (in terms of nuclide specific mass or surface related activity values). A set of levels has been developed in IAEA Safety Guide RSG-1.7 [5] (for details on the derivation see IAEA Safety Report 44 [6]) as general clearance levels and exemption values for large quantities for inclusion in the IAEA BSS [4]. This set of values has been proposed by the European Commission (EC) as an internationally harmonised set of clearance levels that could be incorporated into the BSS. Furthermore, the EC has proposed to use this set of values also as a new set of exemption values, replacing the current set of mass related exemption values of Annex I Table A Column 3 of the BSS. It was, however, decided that the technical background and further details of the derivation of the set of values should be evaluated before actually incorporating these values into the EURATOM BSS. Therefore, a study was commissioned by the European Commission, DG TREN, and has been prepared by Brenk Systemplanung GmbH in 2008 [7]. This study provides a basis for a decision whether the levels of RS-G-1.7 could be used as clearance levels for unconditional clearance and as a replacement for mass related exemption values in the BSS. It also compares the background and approach of the relevant documents (RS-G-1.7 and SR 44 of the IAEA and RP 122 part I [2] of the European Commission) and the way in which clearance levels have been derived (analysis of scenarios, parameter values and calculation codes). The comparison is performed and evaluated on a nuclide-specific basis, and conclusions are drawn where further evaluation of the values of RS-G-1.7 would be needed. In a second part, the study evaluates and discusses implications for practices not requiring reporting or authorisation under the current exemption values

  18. Søgning og navigation

    DEFF Research Database (Denmark)

    Grauballe, Henning; Strunck, Kirsten Marie

    6 udvalgte testposter undersøges i 97 danske folkebibliotekers webkataloger med henblik på at afdække, hvordan disse testposters kontrollerede data udnyttes som hyperlinks til navigation og til videresøgning på ”Noget der ligner”. Undersøgelsen viser, at webkatalogerne især fokuserer på at udnytte...... opstillingsdata og udvalgte emnedata til navigation. Dermed udnyttes det samlede potentiale i de kontrollerede data ikke til at imødekomme brugernes forventninger til navigation ved hjælp af hyperlinks på Web’en. Undersøgelsen indikerer desuden, at der er en tæt sammenhæng mellem det konkrete bibliotekssystem...

  19. GPS Navigation and Tracking Device

    Directory of Open Access Journals (Sweden)

    Yahya Salameh Khraisat

    2011-10-01

    Full Text Available Since the introduction of GPS Navigation systems in the marketplace, consumers and businesses have been coming up with innovative ways to use the technology in their everyday life. GPS Navigation and Tracking systems keep us from getting lost when we are in strange locations, they monitor children when they are away from home, keep track of business vehicles and can even let us know where a philandering partner is at all times. Because of this we attend to build a GPS tracking device to solve the mentioned problems. Our work consists of the GPS module that collects data from satellites and calculates the position information before transmitting them to the user’s PC (of Navigation system or observers (of Tracking System using wireless technology (GSM.

  20. Application of clearance automatic laser inspection system to clearance measurement of concrete waste

    International Nuclear Information System (INIS)

    Recently, the Clearance Automatic Laser Inspection System (CLALIS) has been developed for the clearance measurement of metal scraps. It utilizes three-dimensional (3D) laser scanning, y-ray measurement and Monte Carlo calculation, and has outstanding detection ability. For the clearance measurement of concrete segments, the effect of background (BG) gamma rays from natural radionuclides in the measurement target, such as K-40 and the radioactive decay products of Th-232 and U-238, should be compensated for to ensure adequate waste management. Since NE102A plastic scintillation detectors are used for y-ray measurement in CLALIS, it is impossible to distinguish between count rates of natural radionuclides and contaminants on the basis of gamma-ray energy information. To apply CLALIS to the clearance measurement of concrete segments, the original activity evaluation method was improved by adding a new compensation procedure. In this procedure, BG count rate due to natural radionuclides is estimated by a Monte Carlo calculation with pre-analyzed data of a representative sample of the measurement target. The activity concentration of natural radionuclides in concrete differs markedly depending on the production location of its components, such as cement and aggregates. In this study, using six mock concrete waste samples, which were composed of cement and fine aggregate from various production locations, the accuracy of BG compensation was experimentally estimated. In addition, the accuracy of calibration for concrete waste was also estimated using a number of mock concrete segments of small and large triangular prisms. By considering the uncertainties of BG compensation and calibration, the detection limit of CLALIS for concrete waste was estimated. As a result, it was revealed that CLALIS could be applied to the clearance measurement of concrete segments when the mass of the measurement target is greater than approximately 1.1 kg and the key radionuclide is Co-60

  1. Surgical navigation in oral implantology.

    Science.gov (United States)

    Miller, Robert J; Bier, Jurgen

    2006-03-01

    The ability to generate 3-dimensional volumetric images of the maxillofacial area has allowed surgeons to evaluate anatomy before surgery and plan for the placement of implants in ideal positions. However, the ability to transfer that information to surgical reality has been the most challenging part of implant dentistry. With the advent of computer-assisted surgery, the surgeon may now navigate through the entire implant procedure with extremely high accuracy. A new portable laptop navigated system for oral implantology is discussed as an adjunct for complex implant cases. PMID:16569960

  2. Observability of Inertial Navigation System

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    To improve the observability of strapdown inertial navigation system and the effectiveness of Kalman filter in the navigation system, the method of estimating the observability is analyzed based on eigenvalues and eigenvectors which are proved to be availabe, on this basis two-position alignment technigue is applied. The simulation shows that two-position alignment really makes the system's observability change from being incomplete to being complete, and the test method based on eigenvalues and eigenvectors is available to determine the observability of every state vector.

  3. Navigation with a visual memory

    OpenAIRE

    Remazeilles, Anthony

    2004-01-01

    This work deals with autonomous robotic navigation. A robotic system that moves on its own must be able to localise itself in the environment, so as to define a path to follow, and also to control its motion in order to reach a desired position. A vision based-approach is chosen, by onsidering robotic systems with an on-board camera. The navigation space is represented in a topological way by an image database acquired during a learning step. Thus, the robot localisation is directly related t...

  4. The constructional conception of the effectiveness of navigational service rising for navigation on inland water routes

    OpenAIRE

    I. V. Tykhonov

    2010-01-01

    Constructional conception of rising of the effectiveness of navigational service on inland water routes is described. The article demonstrates that using of this conception and informational recourses permit to raise the effectiveness of navigational service of safety of navigation

  5. An accredited infrastructure for clearance of decommissioning waste

    International Nuclear Information System (INIS)

    The nuclear research reactors and a hot-cell facility at the Riso site in Denmark have been closed and are in the process of being decommissioned. This has prompted the development of an accredited infrastructure called the Clearance Function. This function is responsible for the activity concentration measurements of the clearance candidates and for the demonstration of compliance with the clearance levels for the released objects. The Clearance Function comprises laboratory facilities, measuring equipment, measuring procedures, waste handling software, software for clearance related calculations and trained personnel. An accreditation of the Clearance Function has been granted from the accreditation body, DANAK, according to the international standard ISO/IEC 17025:2005. DANAK is a member of ILAC, the International Laboratory Accreditation Cooperation. The Clearance Function has been accredited to measure surface-specific and mass-specific activities using surface contamination monitors and high purity germanium detectors. The germanium detectors are characterised and in each measurement they are calibrated using the ISOCS (registered) calibration software. Activity concentration measurements can be made on items as a whole (one or several combined measurements) or on samples from an item. In the latter case a statistical method is used to evaluate whether the activity concentration is above or below the clearance level. The paper describes the different elements of the Clearance Function and the processing of items through the flow routes depending on the likely activity content and the distribution of activity. It is shown how uncertainties are incorporated in the clearance criteria. Experience from the first year of operation of the Clearance Function is reported. (author)

  6. An accredited infrastructure for clearance of decommissioning waste

    International Nuclear Information System (INIS)

    The nuclear research reactors and a hot-cell facility at the Riso site in Denmark have been closed and are in the process of being decommissioned. This has prompted the development of an accredited infrastructure called the Clearance Function. This function is responsible for the activity concentration measurements of the clearance candidates and for the demonstration of compliance with the clearance levels for the released objects. The Clearance Function comprises laboratory facilities, measuring equipment, measuring procedures, waste handling software, software for clearance related calculations and trained personnel. An accreditation of the Clearance Function has been granted from the accreditation body, DANAK, according to the international standard ISO/IEC 17025:2005. DANAK is a member of ILAC, the International Laboratory Accreditation Cooperation. The Clearance Function has been accredited to measure surface-specific and mass-specific activities using surface contamination monitors and high purity germanium detectors. The germanium detectors are characterised and in each measurement they are calibrated using the ISOCS calibration software. Activity concentration measurements can be made on items as a whole (one or several combined measurements) or on samples from an item. In the latter case a statistical method is used to evaluate whether the activity concentration is above or below the clearance level. The paper describes the different elements of the Clearance Function and the processing of items through the flow routes depending on the likely activity content and the distribution of activity. It is shown how uncertainties are incorporated in the clearance criteria. Experience from the first year of operation of the Clearance Function is reported. (author)

  7. Celestial navigation in a nutshell

    CERN Document Server

    Schlereth, Hewitt

    2000-01-01

    Celestial Navigation in a Nutshell demonstrates how to take sights by the sun, moon, stars, and planets, discussing the advantages and disadvantages of each method. The reader is taken carefully through several examples and situational illustrations, making this a most effective self-teaching guide. Common errors are reviewed and several tips on how to improve accuracy are given.

  8. Conceptual Grounds of Navigation Safety

    Directory of Open Access Journals (Sweden)

    Vladimir Torskiy

    2016-04-01

    Full Text Available The most important global problem being solved by the whole world community nowadays is to provide sustainable mankind development. Recent research in the field of sustainable development states that civilization safety is impossible without transfer sustainable development. At the same time, sustainable development (i.e. preservation of human culture and biosphere is impossible as a system that serves to meet economical, cultural, scientific, recreational and other human needs without safety. Safety plays an important role in sustainable development goals achievement. An essential condition of effective navigation functioning is to provide its safety. The “prescriptive” approach to the navigation safety, which is currently used in the world maritime field, is based on long-term experience and ship accidents investigation results. Thus this approach acted as an the great fact in reduction of number of accidents at sea. Having adopted the International Safety Management Code all the activities connected with navigation safety problems solution were transferred to the higher qualitative level. Search and development of new approaches and methods of ship accidents prevention during their operation have obtained greater importance. However, the maritime safety concept (i.e. the different points on ways, means and methods that should be used to achieve this goal hasn't been formed and described yet. The article contains a brief review of the main provisions of Navigation Safety Conceptions, which contribute to the number of accidents and incidents at sea reduction.

  9. Navigation system for interstitial brachytherapy

    International Nuclear Information System (INIS)

    The purpose of the stud was to develop a computed tomography (CT) based electromagnetic navigation system for interstitial brachytherapy. This is especially designed for situations when needles have to be positioned adjacent to or within critical anatomical structures. In such instances interactive 3D visualisation of the needle positions is essential. The material consisted of a Polhemus electromagnetic 3D digitizer, a Pentium 200 MHz laptop and a voice recognition for continuous speech. In addition, we developed an external reference system constructed of Perspex which could be positioned above the tumour region and attached to the patient using a non-invasive fixation method. A specially designed needle holder and patient bed were also developed. Measurements were made on a series of phantoms in order to study the efficacy and accuracy of the navigation system. The mean navigation accuracy of positioning the 20.0 cm length metallic needles within the phantoms was in the range 2.0-4.1 mm with a maximum of 5.4 mm. This is an improvement on the accuracy of a CT-guided technique which was in the range 6.1-11.3 mm with a maximum of 19.4 mm. The mean reconstruction accuracy of the implant geometry was 3.2 mm within a non-ferromagnetic environment. We found that although the needles were metallic this did not have a significant influence. We also found for our experimental setups that the CT table and operation table non-ferromagnetic parts had no significant influence on the navigation accuracy. This navigation system will be a very useful clinical tool for interstitial brachytherapy applications, particularly when critical structures have to be avoided. It also should provide a significant improvement on our existing technique

  10. 14 CFR 29.411 - Ground clearance: tail rotor guard.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground clearance: tail rotor guard. 29.411... System Loads § 29.411 Ground clearance: tail rotor guard. (a) It must be impossible for the tail rotor to contact the landing surface during a normal landing. (b) If a tail rotor guard is required to...

  11. 14 CFR 27.411 - Ground clearance: tail rotor guard.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground clearance: tail rotor guard. 27.411... System Loads § 27.411 Ground clearance: tail rotor guard. (a) It must be impossible for the tail rotor to contact the landing surface during a normal landing. (b) If a tail rotor guard is required to...

  12. 48 CFR 2452.237-75 - Clearance of contractor personnel.

    Science.gov (United States)

    2010-10-01

    ... personnel. 2452.237-75 Section 2452.237-75 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND... Clauses 2452.237-75 Clearance of contractor personnel. As prescribed in 2437.110(e), insert the following clause in solicitations and contracts. Clearance of Contractor Personnel (OCT 1999) (a) General....

  13. 48 CFR 32.502-2 - Contract finance office clearance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract finance office clearance. 32.502-2 Section 32.502-2 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... finance office clearance. The contracting officer shall obtain the approval of the contract finance...

  14. 48 CFR 1432.502-2 - Contract finance office clearance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract finance office clearance. 1432.502-2 Section 1432.502-2 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR... finance office clearance. The CO shall obtain approval of the bureau finance office prior to...

  15. 48 CFR 832.502-2 - Contract finance office clearance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract finance office clearance. 832.502-2 Section 832.502-2 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS... finance office clearance. Contracting officers must obtain approval from the DSPE before taking...

  16. Mechanistic evaluation of virus clearance by depth filtration.

    Science.gov (United States)

    Venkiteshwaran, Adith; Fogle, Jace; Patnaik, Purbasa; Kowle, Ron; Chen, Dayue

    2015-01-01

    Virus clearance by depth filtration has not been well-understood mechanistically due to lack of quantitative data on filter charge characteristics and absence of systematic studies. It is generally believed that both electrostatic interactions and sized based mechanical entrapment contribute to virus clearance by depth filtration. In order to establish whether the effectiveness of virus clearance correlates with the charge characteristics of a given depth filter, a counter-ion displacement technique was employed to determine the ionic capacity for several depth filters. Two depth filters (Millipore B1HC and X0HC) with significant differences in ionic capacities were selected and evaluated for their ability to eliminate viruses. The high ionic capacity X0HC filter showed complete porcine parvovirus (PPV) clearance (eliminating the spiked viruses to below the limit of detection) under low conductivity conditions (≤2.5 mS/cm), achieving a log10 reduction factor (LRF) of > 4.8. On the other hand, the low ionic capacity B1HC filter achieved only ∼2.1-3.0 LRF of PPV clearance under the same conditions. These results indicate that parvovirus clearance by these two depth filters are mainly achieved via electrostatic interactions between the filters and PPV. When much larger xenotropic murine leukemia virus (XMuLV) was used as the model virus, complete retrovirus clearance was obtained under all conditions evaluated for both depth filters, suggesting the involvement of mechanisms other than just electrostatic interactions in XMuLV clearance. PMID:25683459

  17. Clearance systems in the brain-implications for Alzheimer disease.

    Science.gov (United States)

    Tarasoff-Conway, Jenna M; Carare, Roxana O; Osorio, Ricardo S; Glodzik, Lidia; Butler, Tracy; Fieremans, Els; Axel, Leon; Rusinek, Henry; Nicholson, Charles; Zlokovic, Berislav V; Frangione, Blas; Blennow, Kaj; Ménard, Joël; Zetterberg, Henrik; Wisniewski, Thomas; de Leon, Mony J

    2015-08-01

    Accumulation of toxic protein aggregates-amyloid-β (Aβ) plaques and hyperphosphorylated tau tangles-is the pathological hallmark of Alzheimer disease (AD). Aβ accumulation has been hypothesized to result from an imbalance between Aβ production and clearance; indeed, Aβ clearance seems to be impaired in both early and late forms of AD. To develop efficient strategies to slow down or halt AD, it is critical to understand how Aβ is cleared from the brain. Extracellular Aβ deposits can be removed from the brain by various clearance systems, most importantly, transport across the blood-brain barrier. Findings from the past few years suggest that astroglial-mediated interstitial fluid (ISF) bulk flow, known as the glymphatic system, might contribute to a larger portion of extracellular Aβ (eAβ) clearance than previously thought. The meningeal lymphatic vessels, discovered in 2015, might provide another clearance route. Because these clearance systems act together to drive eAβ from the brain, any alteration to their function could contribute to AD. An understanding of Aβ clearance might provide strategies to reduce excess Aβ deposits and delay, or even prevent, disease onset. In this Review, we describe the clearance systems of the brain as they relate to proteins implicated in AD pathology, with the main focus on Aβ. PMID:26195256

  18. 5 CFR 720.307 - Interagency report clearance.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Interagency report clearance. 720.307 Section 720.307 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) AFFIRMATIVE EMPLOYMENT PROGRAMS Disabled Veterans Affirmative Action Program § 720.307 Interagency report clearance. The...

  19. 48 CFR 952.204-73 - Facility clearance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Facility clearance. 952.204-73 Section 952.204-73 Federal Acquisition Regulations System DEPARTMENT OF ENERGY CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Text of Provisions and Clauses 952.204-73 Facility clearance. As prescribed in 904.404(d)(5),...

  20. Benefits of Improved HP Turbine Active Clearance Control

    Science.gov (United States)

    Ruiz, Rafael; Albers, Bob; Sak, Wojciech; Seitzer, Ken; Steinetz, Bruce M.

    2007-01-01

    As part of the NASA Propulsion 21 program, GE Aircraft Engines was contracted to develop an improved high pressure turbine(HPT) active clearance control (ACC) system. The system is envisioned to minimize blade tip clearances to improve HPT efficiency throughout the engine operation range simultaneously reducing fuel consumption and emissions.

  1. Allometric scaling for predicting human clearance of bisphenol A

    International Nuclear Information System (INIS)

    The investigation of interspecies differences in bisphenol A (BPA) pharmacokinetics (PK) may be useful for translating findings from animal studies to humans, identifying major processes involved in BPA clearance mechanisms, and predicting BPA PK parameters in man. For the first time, a large range of species in terms of body weight, from 0.02 kg (mice) to 495 kg (horses) was used to predict BPA clearance in man by an allometric approach. BPA PK was evaluated after intravenous administration of BPA in horses, sheep, pigs, dogs, rats and mice. A non-compartmental analysis was used to estimate plasma clearance and steady state volume of distribution and predict BPA PK parameters in humans from allometric scaling. In all the species investigated, BPA plasma clearance was high and of the same order of magnitude as their respective hepatic blood flow. By an allometric scaling, the human clearance was estimated to be 1.79 L/min (equivalent to 25.6 mL/kg.min) with a 95% prediction interval of 0.36 to 8.83 L/min. Our results support the hypothesis that there are highly efficient and hepatic mechanisms of BPA clearance in man. - Highlights: • Allometric scaling was used to predict BPA pharmacokinetic parameters in humans. • In all species, BPA plasma clearance approached hepatic blood flow. • Human BPA clearance was estimated to be 1.79 L/min

  2. Radioaerosol delivery and clearance in patients with respiratory failure

    International Nuclear Information System (INIS)

    A technique for radioaerosol delivery to patients requiring mechanical ventilation is described. Ventilation images and pulmonary radioaerosol clearance rates were successfully obtained in 35 patients regardless of ventilator type or level of positive end-expiratory pressure (PEEP). Those patients with noncardiogenic pulmonary edema (NPE) had significantly increased clearance rates relative to those patients in whom NPE was not present

  3. Allometric scaling for predicting human clearance of bisphenol A

    Energy Technology Data Exchange (ETDEWEB)

    Collet, Séverine H., E-mail: s.collet@envt.fr; Picard-Hagen, Nicole, E-mail: n.hagen-picard@envt.fr; Lacroix, Marlène Z., E-mail: m.lacroix@envt.fr; Puel, Sylvie, E-mail: s.puel@envt.fr; Viguié, Catherine, E-mail: c.viguie@envt.fr; Bousquet-Melou, Alain, E-mail: a.bousquet-Melou@envt.fr; Toutain, Pierre-Louis, E-mail: pltoutain@wanadoo.fr; Gayrard, Véronique, E-mail: v.gayrard@envt.fr

    2015-05-01

    The investigation of interspecies differences in bisphenol A (BPA) pharmacokinetics (PK) may be useful for translating findings from animal studies to humans, identifying major processes involved in BPA clearance mechanisms, and predicting BPA PK parameters in man. For the first time, a large range of species in terms of body weight, from 0.02 kg (mice) to 495 kg (horses) was used to predict BPA clearance in man by an allometric approach. BPA PK was evaluated after intravenous administration of BPA in horses, sheep, pigs, dogs, rats and mice. A non-compartmental analysis was used to estimate plasma clearance and steady state volume of distribution and predict BPA PK parameters in humans from allometric scaling. In all the species investigated, BPA plasma clearance was high and of the same order of magnitude as their respective hepatic blood flow. By an allometric scaling, the human clearance was estimated to be 1.79 L/min (equivalent to 25.6 mL/kg.min) with a 95% prediction interval of 0.36 to 8.83 L/min. Our results support the hypothesis that there are highly efficient and hepatic mechanisms of BPA clearance in man. - Highlights: • Allometric scaling was used to predict BPA pharmacokinetic parameters in humans. • In all species, BPA plasma clearance approached hepatic blood flow. • Human BPA clearance was estimated to be 1.79 L/min.

  4. Study of global operational needs for mine clearance equipment

    Science.gov (United States)

    Blagden, Paddy M.

    2003-09-01

    The Geneva International Centre for Humanitarian Demining studied the needs of landmine clearance groups for equipment to carry out specific functions of mine clearance. This was done on a global level, and useful results were obtained, which will provide the basis for further analysis.

  5. 33 CFR 401.54 - Interference with navigation aids.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Interference with navigation aids. 401.54 Section 401.54 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION... with navigation aids. (a) Aids to navigation shall not be interfered with or used as moorings. (b)...

  6. 33 CFR 67.35-10 - Private aids to navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Private aids to navigation. 67.35-10 Section 67.35-10 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION AIDS TO NAVIGATION ON ARTIFICIAL ISLANDS AND FIXED STRUCTURES Applications §...

  7. 33 CFR 100.45 - Establishment of aids to navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Establishment of aids to navigation. 100.45 Section 100.45 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... navigation. The District Commander will establish and maintain only those aids to navigation necessary...

  8. Guidance of clearance related standards in reactor facilities

    International Nuclear Information System (INIS)

    The reactor regulation law was amended in May 2005 to provide for the clearance system. The regulatory body confirmed radioactivity concentration of material and allowed the material be classified as 'material cleared from regulatory control'. The procedure of confirmation consisted of two steps; 1) methodology and 2) results, of measurement and assessment. Clearance related standards were issued as ordinance of Ministry and NISA information notice, which specified radioactive nuclides, radioactivity concentration, evaluation unit, how to decide radioactivity concentration, radiation measurement equipment and control of object material. This report was guidance of clearance related standards in reactor facilities with explanatory notes. By applying the clearance system, material of insignificant radiation level, which was part of concrete or metals generated from decommissioning of reactor facilities, could be released from regulatory control of radioactive waste as clearance material, and recycle of such material could result in reduction of radioactive waste amount. (T. Tanaka)

  9. Calculation of the renal clearance by dynamic measurement of the excreted activity

    International Nuclear Information System (INIS)

    Aim: In this paper we present a new method to measure the renal slope-clearance of Tc-99m-MAG-3 in a single-shot model (Excretion-clearance). Method: A renal scintigraphy with Tc-99m-MAG-3 was performed in 22 patients. The excreted activity of the tracer in the kidneys and the bladder was dynamically measured using a double-head gamma-camera. Additionally, the total absorption over the kidneys and the bladder was determined. The Excretion-clearance was calculated in a differential and an integral variant. Simultaneously the 2-compartment-clearance (Sapirstein-clearance), the Oberhausen-clearance and the Bubeck-clearance were calculated. Results: The Sapirstein-clearance is considered as the 'goldstandard' in a single-shot modell. The correlation of the Bubeck-clearance and the Oberhausen-clearance ranged from r=0.96 to r=0.97, the Excretion-clearance (differential-method) correlated with r=0.90. The absolute difference of the clearance-values was lowest comparing the Bubeck-clearance with the Sapirstein-clearance with an average difference of 11%, whereas the Excretion-clearance revealed at least an average difference of 21% and the Oberhausen-clearance of 24%. Discussion: The Excretion-clearance requires a more complicated protocoll measuring the clearance in comparison to the Bubeck-clearance. The results of the excretion-clearance differ more from the Sapirstein-clearance with regard to the examined patient population than the Bubeck-clearance. Regarding the theoretical basis of the methods, we expect advantages of the Excretion-clearance compared with the Bubeck-clearance in patients with compartmental disproportion or with a low clearance. We are going to prove this in combination with the above mentioned methodical improvements in a further study. (orig.)

  10. Analysis of conservativity analysis for clearance levels. Final report

    International Nuclear Information System (INIS)

    When deriving clearance levels for material from nuclear installations it is necessary to proceed with a certain degree of conservativity. This can, however, differ between various sets of clearance levels leading to inconsistencies between clearance pathways. The aim of the work therefore is to compare levels of conservativity for the following two sets of clearance levels: clearance levels for disposal as conventional waste and for metallic materials for recycling/reuse. A method was developed to quantify the degree of conservativity and make it comparable. The actual and future situation for disposal of (conventional) wastes in Germany was analysed. In addition, the masses, nuclide vectors, geographical distribution etc. for slightly radioactive material being cleared for conventional disposal was analysed and modelled and the resulting dose distributions were calculated. The values for the clearance levels were taken from the 1995 recommendation by the German Commission on Radiation Protection (SSK). By using realistic scenarios, the exposure was calculated for the personnel on the landfills and for persons of the general public being exposed via groundwater pathways. It could be shown that the trivial dose range will not be exceeded even if the masses of cleared material per landfill site exceed 100 Mg/a. Because of the types and distribution of nuclear installations in Germany and because of the nuclide vectors it is therefore not necessary to limit the masses per landfill sites. Clearance levels that are determined by the exposure pathways external exposure to and the inhalation of dust by the landfill personnel show a similar level of conservativity as those for metal scrap. This means that the clearance levels for gamma emitting nuclides are not overly restrictive. Although radiologically justified, raising the clearance levels would not lead to an increase of the material quantities because other nuclides of the respective nuclide vectors are limiting. In

  11. Navigation in Cross-cultural business relationships

    DEFF Research Database (Denmark)

    Andersen, Poul Houman

    2001-01-01

    Cross-cultural business navigation concerns the process of handling the complexity of several interacting cultural spheres of influence......Cross-cultural business navigation concerns the process of handling the complexity of several interacting cultural spheres of influence...

  12. Indirect assessment of web navigation success

    OpenAIRE

    Gwizdka, Jacek; Spence, Ian

    2005-01-01

    Despite much research on hypertext and web navigation, relatively little is known about the relationship between web navigation strategies and success. We present two exploratory studies designed to explore the relationships between several web navigation metrics that are based on similarity to an optimal path to predict task success. The data suggest that the relationships between these measures depend on the particular web navigation task.

  13. Sniffing Around for Providing Navigation Assistance

    OpenAIRE

    Herder, E.

    2004-01-01

    In this paper we describe an approach to adaptive navigation assistance that is meant to enhance a user’s information scent. The navigation assistance is composed of a combination of predictive user navigation modeling and common information retrieval methods. Besides assistance in forward browsing, the assistant helps users in deciding when to switch to searching or backtracking, while taking their navigation preferences into account.

  14. Novel Environmental Features for Robust Multisensor Navigation

    OpenAIRE

    Walter, D. J.; Groves, P. D.; Mason, R J; Harrison, J.; J. Woodward; Wright, P

    2013-01-01

    Many navigation techniques have now become so reliant on GNSS that there is no back up when there is limited or no signal reception. If there is interference, intentional or otherwise, with the signal, navigation could be lost or become misleading [1]. Other navigation techniques harness different technologies such as Wi-Fi [2], eLoran and inertial navigation. However, each of these techniques has its own limitations, such as coverage, degradation in urban areas or solution drift [3]. Therefo...

  15. Navigation based on symbolic space models

    OpenAIRE

    Baras, Karolina; Moreira, Adriano; Meneses, Filipe

    2010-01-01

    Existing navigation systems are very appropriate for car navigation, but lack support for convenient pedestrian navigation and cannot be used indoors due to GPS limitations. In addition, the creation and the maintenance of the required models are costly and time consuming, and are usually based on proprietary data structures. In this paper we describe a navigation system based on a human inspired symbolic space model. We argue that symbolic space models are much easier...

  16. Nuclear regulation. NRC's security clearance program can be strengthened

    International Nuclear Information System (INIS)

    Because of the national security implications of its programs, the Nuclear Regulatory Commission (NRC) investigates the background of its employees and consultants as well as others to ensure that they are reliable and trustworthy. If the investigation indicates that an employee will not endanger national security, NRC grants a security clearance that allows access to classified information, material, and facilities. NRC also requires periodic checks for some clearance holders to ensure their continued clearance eligibility. The Chairman, Subcommittee on Environment, Energy, and Natural Resources, House Committee on Government Operations, asked GAO to review NRC's personnel security clearance program and assess the procedures that NRC uses to ensure that those who operate nuclear power plants do not pose a threat to the public. The Atomic Energy Act of 1954 requires NRC to conduct background investigations of its employees and consultants as well as others who have access to classified information, material, or facilities. To do this, NRC established a personnel security clearance program. Under NRC policies, a security clearance is granted after the Office of Personnel Management (OPM) or the Federal Bureau of Investigation checks the background of those applying for an NRC clearance. NRC also periodically reassesses the integrity of those holding the highest level clearance. NRC employees, consultants, contractors, and licensees as well as other federal employees hold approximately 10,600 NRC clearances. NRC does not grant clearances to commercial nuclear utility employees unless they require access to classified information or special nuclear material. However, the utilities have voluntarily established screening programs to ensure that their employees do not pose a threat to nuclear plants. NRC faces a dilemma when it hires new employees. Although its policy calls for new hires to be cleared before they start work, the security clearance process takes so long

  17. Observability during planetary approach navigation

    Science.gov (United States)

    Bishop, Robert H.; Burkhart, P. Daniel; Thurman, Sam W.

    1993-01-01

    The objective of the research is to develop an analytic technique to predict the relative navigation capability of different Earth-based radio navigation measurements. In particular, the problem is to determine the relative ability of geocentric range and Doppler measurements to detect the effects of the target planet gravitational attraction on the spacecraft during the planetary approach and near-encounter mission phases. A complete solution to the two-dimensional problem has been developed. Relatively simple analytic formulas are obtained for range and Doppler measurements which describe the observability content of the measurement data along the approach trajectories. An observability measure is defined which is based on the observability matrix for nonlinear systems. The results show good agreement between the analytic observability analysis and the computational batch processing method.

  18. 06421 Abstracts Collection -- Robot Navigation

    OpenAIRE

    Fekete, Sándor; Fleischer, Rudolf; Klein, Rolf; Lopez-Ortiz, Alejandro

    2007-01-01

    From 15.10.06 to 20.10.06, the Dagstuhl Seminar 06421 ``Robot Navigation''generate automatically was held in the International Conference and Research Center (IBFI), Schloss Dagstuhl. During the seminar, several participants presented their current research, and ongoing work and open problems were discussed. Abstracts of the presentations given during the seminar as well as abstracts of seminar results and ideas are put together in this paper. The first section describes the...

  19. Interplanetary spacecraft navigation using pulsars

    OpenAIRE

    Deng, X. P.; Hobbs, G.; You, X. P.; M. T. Li; Keith, M. J.; Shannon, R. M.; Coles, W.; Manchester, R. N.; J.H. Zheng; Yu, X. Z.; Gao, D.; Wu, X; Chen, D.

    2013-01-01

    We demonstrate how observations of pulsars can be used to help navigate a spacecraft travelling in the solar system. We make use of archival observations of millisecond pulsars from the Parkes radio telescope in order to demonstrate the effectiveness of the method and highlight issues, such as pulsar spin irregularities, which need to be accounted for. We show that observations of four millisecond pulsars every seven days using a realistic X-ray telescope on the spacecraft throughout a journe...

  20. Safety effects of navigation systems.

    OpenAIRE

    2009-01-01

    Increasing numbers of drivers are using navigation systems in their cars. The advantages to the user are obvious: you can get to your destination via the fastest and shortest route. This reduces stress and exposure to other traffic. However, there are also some (unintended) negative effects. For example, using the system while driving can distract your attention from other traffic. The system sometimes directs traffic through small centres of habitation or along unsuitable roads. Moreover, ti...

  1. Robotic perception for autonomous navigation

    OpenAIRE

    Furlan,

    2014-01-01

    This thesis presents the research work the author carried on during his PhD on the topic of robotic perception for autonomous navigation. In particular, the efforts focus on the Self-Localization, Scene Understanding and Object Detection and Tracking problems, proposing for each of these three topics one or more approaches that present an improvement over the state-of-the-art. In some cases the proposed approaches mutually exploit the generated information to improve the quality of the final ...

  2. 06421 Executive Summary -- Robot Navigation

    OpenAIRE

    Fekete, Sándor; Fleischer, Rudolf; Klein, Rolf; Lopez-Ortiz, Alejandro

    2007-01-01

    For quite a number of years, researchers from various fields have studied problems motivated by Robot Navigation. People in Online Algorithms have developed strategies that can deal with the inherent lack of information an autonomous robot encounters, as it sets out to perform a task in an unknown environment. Computational Geometers have obtained many results on the efficient planning of collision-free motions, and on visibility problems. Scientists and engineers in Robotics have perfected r...

  3. Orientation and navigation in birds

    OpenAIRE

    Bouwman, H.

    1998-01-01

    How birds orientate and navigate over long distances, remains one of the subjects of ornithology eliciting much interest. Birds use combinations of different sources of information to find direction and position. Some of these are the geomagnetic field, celestial bodies, mosaic and gradient maps, sound, smell, idiotetic information and others. Different species use different combinations of sources. This ability is partially inherent and partially learned.

  4. Orientation and navigation in birds

    Directory of Open Access Journals (Sweden)

    H. Bouwman

    1998-07-01

    Full Text Available How birds orientate and navigate over long distances, remains one of the subjects of ornithology eliciting much interest. Birds use combinations of different sources of information to find direction and position. Some of these are the geomagnetic field, celestial bodies, mosaic and gradient maps, sound, smell, idiotetic information and others. Different species use different combinations of sources. This ability is partially inherent and partially learned.

  5. Navigation in diagnosis and therapy

    International Nuclear Information System (INIS)

    Image-guided navigation for surgery and other therapeutic interventions has grown in importance in recent years. During image-guided navigation a target is detected, localized and characterized for diagnosis and therapy. Thus, images are used to select, plan, guide and evaluate therapy, thereby reducing invasiveness and improving outcomes. A shift from traditional open surgery to less-invasive image-guided surgery will continue to impact the surgical marketplace. Increases in the speed and capacity of computers and computer networks have enabled image-guided interventions. Key elements in image navigation systems are pre-operative 3D imaging (or real-time image acquisition), a graphical display and interactive input devices, such as surgical instruments with light emitting diodes (LEDs). CT and MRI, 3D imaging devices, are commonplace today and 3D images are useful in complex interventions such as radiation oncology and surgery. For example, integrated surgical imaging workstations can be used for frameless stereotaxy during neurosurgical interventions. In addition, imaging systems are being expanded to include decision aids in diagnosis and treatment. Electronic atlases, such as Voxel Man or others derived from the Visible Human Project, combine a set of image data with non-image knowledge such as anatomic labels. Robot assistants and magnetic guidance technology are being developed for minimally invasive surgery and other therapeutic interventions. Major progress is expected at the interface between the disciplines of radiology and surgery where imaging, intervention and informatics converge

  6. Comparative evaluation of iohexol and inulin clearance for glomerular filtration rate determinations

    International Nuclear Information System (INIS)

    The authors have evaluated iohexol as a filtration marker in 150 children. The clearance of iohexol was compared with that of inulin or with a formula clearance. The single-sample clearance of iohexol showed a good correlation with the clearance of inulin. The clearance of iohexol correlated well with the formula clearance. The optimal blood sampling time for iohexol clearance determinations appears to be between 120 and 180 min after injection, at least in patient with relatively normal filtration rates. It is concluded that iohexol clearance is an accurate method of determining the glomerular filtration rate in clinical practice. 25 refs., 5 figs

  7. Measurement of tracheobronchial clearance after sauna in subjects with chronic bronchitis.

    OpenAIRE

    van Hengstum, M; Festen, J.; Corstens, F.

    1991-01-01

    The effect of sauna on tracheobronchial clearance was studied in five male patients with chronic bronchitis by a radioaerosol technique. No enhancement of tracheobronchial clearance could be detected.

  8. Clearance and Exemption- Application in EU Member Status

    International Nuclear Information System (INIS)

    This paper summarises the findings of the European Commission project commissioned to provide information on the application of the concepts of exemption and clearance for practices according to Title III of Council Directive 96/29/EURATOM (Directive) of 13 May 1996 (Directive). The study collated and then evaluated information on the legal instruments and application of exemption and clearance in all EU Member States. It was found that most Member States in the EU have introduced new legislation to address the Directive within the past 2-3 years. Exemption has been implemented by the majority of Member States in a way consistent with Title III of the Directive. The area of greatest variation relates to the introduction of clearance levels. In most Member States clearance levels, when adopted, are not based on values published in guidance from the European Commission. It was found that there is a variation of up to four orders of magnitude between the clearance levels used in some Member States and those recommended in European Commission guidance. It is clear, following the review of implementation in Member States, that there is a need for additional guidance on various aspects of the implementation of the concepts of exemption and clearance; including on surface contamination levels and decay storage. Clearance guidance for small users such as universities and hospitals would also be welcomed. (Author) 9 refs

  9. Secretin enhances [14C]erythritol clearance in unanesthetized dogs

    International Nuclear Information System (INIS)

    To determine the effect of secretin infusion on clearance of inert markers into bile, unanesthetized dogs fitted with Thomas cannulas received continuous infusions of [14C]erythritol and [3H]inulin throughout study. Taurocholic acid administered sequentially at 9.0, 20.0, and 40.0 mumol/min enhanced [14C]erythritol clearance, and GIH secretin (3 units/min) administered along with TCA (40.0 mumol/min) increased [14C]erythritol clearance from 4.9 +/- 1.2 ml/10 min to 6.8 +/- 1.3 ml/10 min (P less than 0.001), but simultaneously measured [3H]inulin clearance was unaltered. Secretin alone also increased [14C]erythritol clearance but did not alter [3H]inulin clearance. The increase in [14C]erythritol clearance per unit increase in bile flow was less during secretin infusion than TCA. Thus, secretin increases [14C]erythritol transport through restricted channels, probably distal to the canaliculi. [14C]Erythritol may not be an accurate marker for canalicular bile flow in dogs during secretin infusion

  10. Distribution and clearance of radioactive aerosol on the nasal mucosa.

    Science.gov (United States)

    McLean, J A; Bacon, J R; Mathews, K P; Thrall, J H; Banas, J M; Hedden, J; Bayne, N K

    1984-03-01

    The distribution and clearance of aerosolized radioactive technetium 99m pertechnate in physiologic buffered saline was analyzed in four human adult asymptomatic volunteers following delivery into one nostril in the same manner as for nasal challenge testing (i.e., 0.1 ml via a 251 DeVilbiss atomizer powered by a compressor delivering 0.10 +/- 0.01 gm/spray). For comparison, squeeze bottles and spray bottles from commercial sources, a 114 and a 127 DeVilbiss atomizer, and a pipette were employed. Lateral imagery via minicomputer processing was used to determine both distribution and clearance of the radiotracer. The counts after 1 minute were lower following pipette delivery than with the other devices. None yielded discernable , wide-spread distribution of aerosol throughout the nasal cavity. Following delivery from the 251 atomizer, mean clearance at 17 minutes was 60.0%. Similar clearance rates were obtained with the other spraying methods except for lower values with the squeeze bottle. Analysis of six hour clearance studies by linear regression showed a relatively rapid initial phase, which is probably due largely to mucociliary clearance, and a prolonged late phase related to the very slow disappearance of residual material located far anteriorly in the nose. Achieving good initial retention and rapid clearance of material deposited anteriorly in the nose are desirable attributes of devices employed for administering materials intranasally. PMID:6328631

  11. Navigation.

    Science.gov (United States)

    Wellman, Bruce; Lipton, Laura

    2000-01-01

    Teachers' quests for more data-based planning, problem solving, and decision making often stumble against limited capacities for engaging in thoughtful interactions, with groups typically lacking process tools, collaborative communication skills, and reflective habits. This article presents a three-phase model for guiding data-driven dialogue in…

  12. Renal function analysis by CT. CT clearance versus [sup 131]I-Hippuran clearance. Eine Nierenfunktionsanalyse durch die Computertomographie. CT-Clearance versus [sup 131]Jod-Hippuran-Clearance

    Energy Technology Data Exchange (ETDEWEB)

    Kaltenborn, H.; Klose, K. (Johannes-Gutenberg-Universitaet Mainz, Radiologische Klinik (Germany))

    1992-06-01

    The CT clearance in a number of urological patients (39 patients, 25 with normal renal function) was studied by means of an ''area under curve'' (AUC) method, using a region of interest. 31 patients were given meglumine ioxithalamate and 8 patients Iopamidol as a contrast medium. Both for total and partial function there was highly significant correlation with isotope clearance with good reproducibility. The difference in the pharmacokinetics of the contrast media affected the absolute clearance values. (orig.).

  13. Clearance from the anterior chamber of RBCs from human diabetics

    International Nuclear Information System (INIS)

    Erythrocytes from diabetic patients manifest decreased deformability and increased adherence. These abnormal membrane properties may diminish the ability of erythrocytes (RBCs) from diabetics to undergo deformation in passage through the trabecular meshwork. Using sodium chromate Cr 51-labeled RBCs from type I diabetic patients with proliferative retinopathy and normal control subjects, we studied RBC clearance from the rabbit anterior chamber. The mean time for 50% clearance (T50) of RBCs from diabetics (76 hours) was significantly longer than that for RBCs from normal subjects (19.5 hours). In this model, RBCs from diabetics have a slower clearance from the anterior chamber than do RBCs from normal subjects

  14. Wind Power and Fault Clearance. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Vikesjoe, Johnny; Messing, Lars (Gothia Power (Sweden))

    2011-04-15

    The increased penetration of wind power will increase the impact of wind power on the grid and thereby increase the importance of a clear guidance concerning the requirements on the protection system of the wind power units and the grid protection in connection to wind power units. The protection system should be able to satisfy the grid connection requirements, set by the TSO (Transmission System Operator) and the grid owners, as well as the general safety and security requirements, such as; personal safety, operational security and economic insurance, i.e. an insurance against economic losses. Vindforsk has appointed Gothia Power AB to perform a study concerning the fault clearance function in connection to wind power installations. The study is divided into two parts; Part 1: The first stage of the project handled the present praxis for the protection, including investigation of legal requirements, operational requirement and personal safety requirement applicable to wind power applications. Proposals for protection requirement for wind power units and the connecting grid are given. Basically 'normal' fault clearance requirements regarding speed, selectivity and redundancy can be used also in applications in connection to wind power. Part 2: The second part of the project results in a guideline for design of protection systems in connection to wind power. In this report mainly part 2 is covered. The main focus is given to clearance of faults in the grid connecting the wind power plants. Regarding internal faults and critical operation states within the wind power plant, a short discussion of feasible protection functions is given. Some critical fault cases in the grid have been identified and discussed: - Undetected islanding and failure of reclosing. There can be a risk of undetected island operation. In such cases it is recommended to use controlled autoreclosing in the vicinity of wind power generation. - Unwanted disconnection of a healthy feeder

  15. Cooperative navigation and localization for multiple UUVs

    Science.gov (United States)

    Zhang, Li-Chuan; Xu, De-Min; Liu, Ming-Yong; Yan, Wei-Sheng

    2009-09-01

    The authors proposed a moving long baseline algorithm based on the extended Kalman filter (EKF) for cooperative navigation and localization of multi-unmanned underwater vehicles (UUVs). Research on cooperative navigation and localization for multi-UUVs is important to solve navigation problems that restrict long and deep excursions. The authors investigated improvements in navigation accuracy. In the moving long base line (MLBL) structure, the master UUV is equipped with a high precision navigation system as a node of the moving long baseline, and the slave UUV is equipped with a low precision navigation system. They are both equipped with acoustic devices to measure relative location. Using traditional triangulation methods to calculate the position of the slave UUV may cause a faulty solution. An EKF was designed to solve this, combining the proprioceptive and exteroceptive sensors. Research results proved that the navigational accuracy is improved significantly with the MLBL method based on EKF.

  16. Spatial navigation in young versus older adults

    Directory of Open Access Journals (Sweden)

    Ivana Gazova

    2013-12-01

    Full Text Available Older age is associated with changes in the brain, including the medial temporal lobe, which may result in mild spatial navigation deficits, especially in allocentric navigation. The aim of the study was to characterize the profile of real-space allocentric (world-centered, hippocampus dependent and egocentric (body-centered, parietal lobe dependent navigation and learning in young vs. older adults, and to assess a possible influence of gender. We recruited healthy participants without cognitive deficits on standard neuropsychological testing, white matter lesions or pronounced hippocampal atrophy: 24 young participants (18-26 years old and 44 older participants stratified as participants 60-70 years old (n=24 and participants 71-84 years old (n=20. All underwent spatial navigation testing in the real-space human analog of the Morris Water Maze, which has the advantage of assessing separately allocentric and egocentric navigation and learning. Of the 8 consecutive trials, trials 2-8 were used to reduce bias by a rebound effect (more dramatic changes in performance between trials 1 and 2 relative to subsequent trials. The participants who were 71-84 years old (p< .001, but not those 60-70 years old, showed deficit in allocentric navigation compared to the young participants. There were no differences in egocentric navigation. All three groups showed spatial learning effect (p´s ≤.01. There were no gender differences in spatial navigation and learning. The linear regression limited to older participants showed linear (β=0.30, p=.045 and quadratic (β=0.30, p=.046 effect of age on allocentric navigation. There was no effect of age on egocentric navigation. These results demonstrate that navigation deficits in older age may be limited to allocentric navigation, whereas egocentric navigation and learning may remain preserved. This specific pattern of spatial navigation impairment may help differentiate normal aging from prodromal Alzheimer

  17. Metabolic clearance rate and urinary clearance of purified beta-core

    International Nuclear Information System (INIS)

    We injected a highly purified preparation of the beta-core molecule, a fragment of hCG beta excreted in pregnancy urine, into five men and three women to determine its kinetic parameters, MCR, and urinary clearance. The beta-core molecule was distributed in an initial volume [1950 +/- 156 (mean +/- SEM) mL/m2 body surface area] approximately equal to the estimated plasma volume. Its disappearance was multiexponential on a semilogarithmic plot, with a rapid phase t1/2 of 3.5 +/- 0.7 min and a slow phase t1/2 of 22.4 +/- 4.2 min. The transit time (the mean time spent by a molecule of beta-core in transit) was 20.6 +/- 2.1 min. The MCR was 192.0 +/- 8.0 mL/min.m2 body surface area. About 5% of the injected dose of beta-core was excreted into the urine in the first 30 min after injection, and low levels of excretion persisted for up to 7 days. The urinary clearance rate of beta-core was 13.7 +/- 1.4 mL/min.m2, accounting for about 8% of the elimination of beta-core from the plasma. The beta-core immunoreactivity in serum and urine was characterized by gel filtration and three independent RIA systems to show that its properties were indistinguishable from those of the injected beta-core. Serum levels of beta-core in pregnant women were less than 0.2 ng/mL, while the amounts excreted in their urine were as much as 5 mg/day. Based on these clearance parameters of beta-core in normal subjects, less than 0.2% of the beta-core excreted in pregnancy urine is derived by urinary clearance of plasma beta-core. Therefore, more than 99% of the beta-core excreted in pregnancy urine is derived from beta-core in a compartment separate from plasma. In particular, these data indicate that there is relatively little placental secretion of beta-core into plasma and that placental secretion does not account for the vast majority of beta-core in pregnancy urine

  18. Scintigraphic examination of mucociliary clearance; Die szintigrafische Untersuchung der mukoziliaeren Clearance

    Energy Technology Data Exchange (ETDEWEB)

    Flierdt, E. van de; Haidl, P. [Gemeinschaftspraxis F. Radiologie und Nuklearmedizin, Muenchen (Germany); Abt. Pneumologie II, Fachkrankenhaus Kloster Grafschaft, Schmallenberg (Germany)

    2009-03-15

    Scintigraphic evaluation of mucociliary clearance (MC) is in consideration of some guidelines (choice of a suitable inhalator and standardization of inhalation procedure) simply practicable. Using a standardized median aerosol with a diameter of approximately 8 {mu}m a dynamic investigation over 60 min is sufficient. Depending on the medical problem MC can be calculated globally or regionally. Indications for the investigation of MC are primary ciliary dyskinesia, persistent cough of unknown origin as well as a possible regional disturbance of MC. Disturbances of MC occur before changes in spirometric pulmonary function tests. Therefore scintigraphic evaluation of MC is suited to early diagnosis of changes in mucociliary removal rates. (orig.)

  19. Emergency Navigation without an Infrastructure

    Directory of Open Access Journals (Sweden)

    Erol Gelenbe

    2014-08-01

    Full Text Available Emergency navigation systems for buildings and other built environments, such as sport arenas or shopping centres, typically rely on simple sensor networks to detect emergencies and, then, provide automatic signs to direct the evacuees. The major drawbacks of such static wireless sensor network (WSN-based emergency navigation systems are the very limited computing capacity, which makes adaptivity very difficult, and the restricted battery power, due to the low cost of sensor nodes for unattended operation. If static wireless sensor networks and cloud-computing can be integrated, then intensive computations that are needed to determine optimal evacuation routes in the presence of time-varying hazards can be offloaded to the cloud, but the disadvantages of limited battery life-time at the client side, as well as the high likelihood of system malfunction during an emergency still remain. By making use of the powerful sensing ability of smart phones, which are increasingly ubiquitous, this paper presents a cloud-enabled indoor emergency navigation framework to direct evacuees in a coordinated fashion and to improve the reliability and resilience for both communication and localization. By combining social potential fields (SPF and a cognitive packet network (CPN-based algorithm, evacuees are guided to exits in dynamic loose clusters. Rather than relying on a conventional telecommunications infrastructure, we suggest an ad hoc cognitive packet network (AHCPN-based protocol to adaptively search optimal communication routes between portable devices and the network egress nodes that provide access to cloud servers, in a manner that spares the remaining battery power of smart phones and minimizes the time latency. Experimental results through detailed simulations indicate that smart human motion and smart network management can increase the survival rate of evacuees and reduce the number of drained smart phones in an evacuation process.

  20. 33 CFR 162.240 - Tongass Narrows, Alaska; navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Tongass Narrows, Alaska; navigation. 162.240 Section 162.240 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY INLAND WATERWAYS NAVIGATION REGULATIONS § 162.240...

  1. 33 CFR 401.97 - Closing procedures and ice navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Closing procedures and ice navigation. 401.97 Section 401.97 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Navigation...

  2. [Bromsulphalein clearance in persons in occupational contact with pesticides].

    Science.gov (United States)

    Mechkov, G; Petkova, V; Zakhariev, N

    1987-01-01

    In 46 persons (sprayers, disinfectors, technicians of the agricultural aviation) the bromsulphalein clearance is traced, during the active work season with pesticides, after the method of Caroly, Nys and Alliot. It is established, that the mean value of bromsulphalein clearance (8.91%) is lower than that of the referent group healthy persons (14.5%). In 14 (31.34%) of the examined the values of the clearance are under 10%. The changes of the last do not correlate closely to other indices of the liver function. As an explanation of the results the authors presuppose general pathogenetic relations between the metabolism of pesticides and of bromsulphalein in the liver cell, with inclusion of glutathione-S-transferase systems. The study allows to give a practical conclusion for the meaning of the bromsulphalein clearance and assessment of the pesticides effect in persons who are in professional contact with them. PMID:3441475

  3. The compliance contact model of cylindrical joints with clearances

    Institute of Scientific and Technical Information of China (English)

    Caishan Liu; Ke Zhang; Lei Yang; Keren Wang

    2005-01-01

    This paper is concerned with the determination of the normal force-displacement (NFD) relation for the contact problem of cylindrical joints with clearance. A simple formulation for this contact problem is developed by modeling the pin as a rigid wedge and the elastic plate as a simple Winkler elastic foundation. The numerical results show that the normal displacement relation based on Hertz theory is only valid for the case of large clearance with a small normal load, and the NFD relation based on Persson theory is only effective in the case of very small clearance. The proposed approximate model in this paper gives better results than Hertz theory and Persson theory in a large range of clearances as seen from the comparison with the results of FEM.

  4. Clearance detector and method for motion and distance

    Energy Technology Data Exchange (ETDEWEB)

    Xavier, Patrick G. (Albuquerque, NM)

    2011-08-09

    A method for correct and efficient detection of clearances between three-dimensional bodies in computer-based simulations, where one or both of the volumes is subject to translation and/or rotations. The method conservatively determines of the size of such clearances and whether there is a collision between the bodies. Given two bodies, each of which is undergoing separate motions, the method utilizes bounding-volume hierarchy representations for the two bodies and, mappings and inverse mappings for the motions of the two bodies. The method uses the representations, mappings and direction vectors to determine the directionally furthest locations of points on the convex hulls of the volumes virtually swept by the bodies and hence the clearance between the bodies, without having to calculate the convex hulls of the bodies. The method includes clearance detection for bodies comprising convex geometrical primitives and more specific techniques for bodies comprising convex polyhedra.

  5. IFNL4 affects clearance of hepatitis C virus

    Science.gov (United States)

    Scientists have discovered a new human interferon gene, Interferon Lambda 4 (IFNL4), that affects clearance of the hepatitis C virus. They also identified an inherited genetic variant within IFNL4 that predicts how people respond to treatment for hepatit

  6. Design Optimization of Ground Clearance of Domestic Cars

    Directory of Open Access Journals (Sweden)

    Debojyoti Mitra

    2010-07-01

    Full Text Available Drag and lift forces plays a vital role in the performance and stability of vehicles. Less drag means less fuel consumption and hence less vehicular pollution. Also, lower lift force means higher chance of adhesion of the car body with the ground causing less overturning of the vehicle, which improves the vehicle performance. Both drag and lift forces can be manipulated by varying the ground clearance of the cars. The present study concentrates on studying the effect of ground clearance on these aerodynamic forces experimentally. Wind tunnel studies with a notch-back car model revealed increase in drag and decrease in lift with increase in ground clearance. Therefore, optimization is required for designing the best ground clearance and a preferable value of the same is thus obtained.

  7. Youth Mobilisation as Social Navigation

    DEFF Research Database (Denmark)

    Vigh, Henrik Erdman

    2010-01-01

    This article sheds light on the mobilisation of young people into conflict. It argues that warfare constitutes a terrain of possibility for urban youth in Guinea‑Bissau, and shows how they navigate war as an event by tactically manoeuvring within the social ties and options that arise in such sit...

  8. Increased Glyburide Clearance in the Pregnant Mouse Model

    OpenAIRE

    Zhou, Lin; ZHANG Yi; Hebert, Mary F.; Unadkat, Jashvant D.; Mao, Qingcheng

    2010-01-01

    Glyburide (GLB) is an oral sulfonylurea, commonly used for the treatment of gestational diabetes mellitus. It has been reported that the clearance of GLB in pregnant women is significantly higher than that in nonpregnant women. The molecular mechanism by which pregnancy increases the clearance of GLB is not known, but it may be caused by increased CYP3A activity. Because liver tissue from pregnant women is not readily available, in the present study, we investigated the mechanism of such preg...

  9. The optimal clearance design of micro-punching die

    Directory of Open Access Journals (Sweden)

    K.S. Lee

    2008-07-01

    Full Text Available Purpose: The purpose of this research paper is focused on the optimal clearance design of micro-punching die by abductive network and SA method.Design/methodology/approach: The punching data (input and wear size (output were collected for a training database. In order to select proper clearance to evaluate the wear of die, the abductive network was used to establish an efficient relationship between input parameters and output result. This can help to predict wear size under any degree of clearance and hence to replace worn punches and dies at the right time. A simulated annealing (SA optimization algorithm with a performance index is then applied to the neural network for searching the optimal clearance parameters, and obtains rather satisfactory result as compared with the corresponding experiment verification.Findings: This study aims to identify the relationship between clearance and service life of micro punches using the Neural Network, and to find relational data involving the service life of punches and punching parameters in non-metal blanking processes. The result can be used to estimate optimal clearance between punch and die for industrial applications.Research limitations/implications: In this study, the practical punching processes with different punching conditions were carried out for a set of training data. A trained model exhibited a relationship between service life and clearance of micro punch and die through an abductive network system. The predicted value of wear by abductive network is very close to the actual experimental value, with an error of less than 8%. This result satisfies the required standard for IC factory production.Originality/value: A good clearance design not only increases the quality of product manufactured, but also reduces product’s burr. As a result, the wear of punches and dies can be greatly reduced and the life expectancy of punching dies increased.

  10. The impact for the clearance of dying cells of CRP

    OpenAIRE

    Janko, Christina

    2012-01-01

    An efficient clearance by phagocytes of apoptotic cells is of major importance to avoid secondary necrosis. The leakage of intracellular autoantigens from improperly cleared cells may provoke inflammation and finally autoimmunity. Therefore, the clearance of dying and dead cells is secured by a plethora of soluble adaptor molecules and receptors that recognize apoptotic cell associated molecular patterns (ACAMP) on the surfaces of the target cells. A pattern recognition molecule of the acute ...

  11. A review and comparison of international exemption and clearance levels

    International Nuclear Information System (INIS)

    The publication of new European Basic Safety Standards by the European Commission and of new International Basic Safety Standards by the IAEA together with other international agencies, has led to increased interest in the application of the concepts of exemption and clearance. This paper discusses the derivation of radionuclide-specific exemption and clearance values for application in various areas of the regulation of radioactive materials. (author)

  12. Early Agriculture: Land Clearance and Climate Effects

    Science.gov (United States)

    Ruddiman, W. F.

    2013-12-01

    inception. Well-dated high-resolution CO2 (and CH4) records from ice cores show gas decreases that correlate closely with major pandemics and civil strife, but show little if any link to temperature or precipitation trends. One significant (and intriguing) discrepancy with the original hypothesis remains. Most of the CO2 rise occurred between 6000 and 2500 years ago, well before the major increase in global population that has been hindcast from geometric models that assume a constant fractional rate of population increase. Some of this discrepancy has been reconciled by historical evidence showing much higher per-capita clearance millennia ago than later in pre-industrial time, resulting in disproportionately large early clearance and CO2 emissions. In addition, DNA studies and archeological syntheses now indicate that early farming populations initially grew at very fast rates favored by environments rich in basic resources (especially fertile soils), but then slowed in later millennia because of growing resource limitations and the effects of pandemics and civil strife in checking population growth. This emerging view of fast-rising early population trends has the potential to account for the early timing of the CO2 increase.

  13. PNP: mining of profile navigational patterns

    Science.gov (United States)

    Li, Hua-Fu; Shan, Man-Kwan

    2002-03-01

    Web usage mining is a key knowledge discovery research and as such has been well researched. So far, this research has focused mainly on databases containing access log data only. However, many real-world databases contain users profile data and current solutions for this situation are still insufficient. In this paper we have a large database containing of user profile information together with user web-pages navigation patterns. The user profile data includes quantitative attributes, such as salary or age, and categorical attributes, such as sex or marital status. We introduce the concept of profile navigation patterns, which discusses the problem of relating user profile information to navigational behavior. An example of such profile navigation pattern might be 20% of married people between age 25 and 30 have the similar navigational behavior , where a, c, h, i, l are web pages in a web site. The navigation patterns may contain the generic traversal behavior, e.g. trend to backward moves, cycles etc. The objective of mining profile navigation patterns is to identify browser profile for web personalization. We give an algorithm for mining such profile navigation patterns. Our method (algorithm PNP) can discover profile navigation patterns efficiently. We also present new inclination measurements to identify the interesting profile navigational patterns. Experimental results show the efficiency and scalability of PNP.

  14. Bronchoscintigraphy and pulmonary clearance of 99mTc-albumin colloid in study of mucociliary clearance

    International Nuclear Information System (INIS)

    A radioaerosol based method for measuring MC was introduced. It included an inhalation protocol that resulted in a predominant deposition of radioaerosol in the central bronchi and two simple procedures of evaluation: 1) a visual semi-quantitative bronchoscintigraphic analysis, and 2) a quantitative analysis of the retention of the radioactivity at different points after the inhalation. The results showed that bronchoscintigraphy was a simple technique that may be used to visualize a stimulation of mucociliary transport in the central airways of individuals that do not suffer from too much mucus hypersecretion. Comparison of the MC between individuals, however, should preferably be performed by the method of quantitative analysis of the radioactivity disappearance. A change of MC was found to be one of the first detectable effects on lung function of tobacco smoking. It could be effectively detected by measurement of radioaerosol clearance both by bronchoscintigraphy and simple quantification of the MC. The MC may be either acutely enhanced, reduced or not changed by smoking. Long-term smoking impairs MC. The enhancement of MC by β2-agonists was very limited in most patients with CF. In the hope of increasing mucus transport in patients with CF, these are treated with various chest physiotherapy techniques. The radioaerosol based method of measurement of MC could assess mucus clearance by chest physiotherapy and cough. (au)

  15. Urinary and metabolic clearances of arginine vasopressin in normal subjects

    International Nuclear Information System (INIS)

    Synthetic arginine vasopressin (AVP) was infused into 11 hydrated normal subjects at five different infusion rates ranging from 10 to 350 μU kg-1 min-1. Each infusion rate was continued for 1 h, and urinary determinations were made on the 30- to 60-min specimens during which time there was no further rise in plasma AVP. Urinary AVP concentrations (μU/ml) and excretion rates (μU/min) increased linearly with increasing infusion rates, and the concentration of AVP in urine increased 120 times more rapid than plasma. Urinary and metabolic clearances of AVP also increased linearly with the maximum urinary clearance being 60.6% of the creatinine clearance. The total metabolic clearance of AVP (including urinary clearance) was 17.8 times that of the urinary clearance of AVP alone. These data clarify the relationships between plasma and urinary AVP in normal hydrated subjects during AVP infusion under steady-state conditions and emphasize the potential advantage of measuring urinary AVP as a monitor of endogenous AVP secretion. AVP was measured by radioimmunoassay

  16. Experimental study on fluid flow in arciform clearance

    Institute of Scientific and Technical Information of China (English)

    邵俊鹏; 汤卉; 贾慧娟

    2002-01-01

    The system damping and dynamic characteristics can be further improved by properly increasing thedamping coefficient ξh. For a special hydraulic damping structure, an arciform damping clearance often used inFCS, a mathematical model has been established for fluid flow using the theory of laminar flow in the clearanceof parallel plates. Analytical calculations are made for fluid flow in the arciform clearance and relational expres-sion is deduced for flow rate along the arciform cleaance height, pressure difference, maximum arciform clear-ance height, the flow rate for the fluid flow in arciform clearance as well, and its simplified formula is obtainedby using the theory of hydrodynamics and the curve - fitting method. This paper consists of two sections: the firstsection focuses on the theoretical analysis by using the simplified mathematical model and the second sectionmainly describes experimental analysis. The simplified formula is corrected with experimental results by consid-erig various boundary conditions of the damping clearance. Experimental results show that this study of arciformdamping clearance is reliable and practical.

  17. A high sensitivity inductive sensor for blade tip clearance measurement

    International Nuclear Information System (INIS)

    A multiplexed inductive sensor consisting of multiple mini-sized planar spiral coils for detecting multiple tip clearances of rotor blades is presented. The sensor measures the tip clearances by monitoring the inductance changes of planar spiral coils caused by the passage of the rotor blades. A resonance frequency division multiplexing technique and parallel LC resonance measurement were applied to the multiple sensor coils, making it feasible to measure multiple tip clearances using only one set of measurement electronics with high sensitivity and resolution. The results from tests conducted on a bench-top test rig have demonstrated that the sensor is capable of simultaneously measuring multiple tip clearances from 0 to 5 mm with a 10 μm resolution at a high rotary speed up to 80 000 RPM. With its high resolution, high sensitivity and capability of monitoring a large number of tip clearances simultaneously, this sensor can potentially be used for advanced active tip clearance control in turbine machinery. (papers)

  18. Model of mucociliary clearance in cystic fibrosis lungs.

    Science.gov (United States)

    Kurbatova, P; Bessonov, N; Volpert, V; Tiddens, H A W M; Cornu, C; Nony, P; Caudri, D

    2015-05-01

    Mucus clearance is a primary innate defense mechanism in the human airways. Cystic fibrosis (CF) is a genetic disease caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CF is characterized by dehydration of airway surface liquid and impaired mucociliary clearance. As a result, microorganisms are not efficiently removed from the airways, and patients experience chronic pulmonary infections and inflammation. We propose a new physiologically based mathematical model of muco-ciliary transport consisting of the two major components of the mucociliary clearance system: (i) periciliary liquid layer (PCL) and (ii) mucus layer. We study mucus clearance under normal conditions and in CF patients. Restoring impaired clearance of airway secretions in one of the major goals of therapy in patients with CF. We consider the action of the aerosolized and inhaled medication dornase alfa, which reduces the viscosity of cystic fibrosis mucus, by selectively cleaving the long DNA strands it contains. The results of the model simulations stress the potential relevance of the location of the drug deposition in the central or peripheral airways. Mucus clearance was increased in case the drug was primarily deposited peripherally, i.e. in the small airways. PMID:25746843

  19. 33 CFR 207.169 - Oklawaha River, navigation lock and dam at Moss Bluff, Fla.; use, administration, and navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Oklawaha River, navigation lock and dam at Moss Bluff, Fla.; use, administration, and navigation. 207.169 Section 207.169 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE...

  20. Intelligent navigation and multivehicle coordination

    Science.gov (United States)

    McKay, Mark D.; Anderson, Matthew O.; Kinoshita, Robert A.; Flann, Nicholas S.

    1999-07-01

    The Idaho National Engineering and Environmental Laboratory (INEEL) and Utah State University's Center for Self-Organizing and Intelligent Systems have developed a team of autonomous robotic vehicles. This paper discusses the development of a strategy that uses a sophisticated, highly intelligent sensor platform to allow centralized coordination between smaller and inexpensive robots. The three components of the multi-agent cooperative scheme are small-scale robots, large-scale robots, and the central control station running a mission and path- planning software. The smaller robots are used for activities where the probability of loss increases, such as Unexploded Ordnance (UXO) or mine detonation. The research is aimed at building simple, inexpensive multi-agent vehicles and an intelligent navigation and multi-vehicle coordination system suitable for UXO, environmental remediation or mine detection. These simplified robots are capable of conducting hunting missions using low-cost positioning sensors and intelligent algorithms. Additionally, a larger sensor-rich intelligent system capable of transporting smaller units to outlying remote sites has been developed. The larger system interfaces to the central control station and provides navigation assistance to multiple low-cost vehicles. Finally, mission and path-planning software serves as the operator control unit, allowing central data collection, map creation and tracking, and an interface to the larger system as well as each smaller unit. The power of this scheme is the ability to scale to the appropriate level for the complexity of the mission.

  1. Optic flow and autonomous navigation.

    Science.gov (United States)

    Campani, M; Giachetti, A; Torre, V

    1995-01-01

    Many animals, especially insects, compute and use optic flow to control their motion direction and to avoid obstacles. Recent advances in computer vision have shown that an adequate optic flow can be computed from image sequences. Therefore studying whether artificial systems, such as robots, can use optic flow for similar purposes is of particular interest. Experiments are reviewed that suggest the possible use of optic flow for the navigation of a robot moving in indoor and outdoor environments. The optic flow is used to detect and localise obstacles in indoor scenes, such as corridors, offices, and laboratories. These routines are based on the computation of a reduced optic flow. The robot is usually able to avoid large obstacles such as a chair or a person. The avoidance performances of the proposed algorithm critically depend on the optomotor reaction of the robot. The optic flow can be used to understand the ego-motion in outdoor scenes, that is, to obtain information on the absolute velocity of the moving vehicle and to detect the presence of other moving objects. A critical step is the correction of the optic flow for shocks and vibrations present during image acquisition. The results obtained suggest that optic flow can be successfully used by biological and artificial systems to control their navigation. Moreover, both systems require fast and accurate optomotor reactions and need to compensate for the instability of the viewed world. PMID:7617428

  2. Importance of different clearance options for the dismantling of the NPP Stade (KKS)

    International Nuclear Information System (INIS)

    As a consequence of the IAEA-Safety Guide RS-G 1.7 is an adaption of the clearance level in European and national German law in preparation. This paper analyse the effect of the different clearance levels of the realisation of the clearance, especially if some conditioned clearance according to German law will not exist further more. (orig.)

  3. Spatial Database Modeling for Indoor Navigation Systems

    Science.gov (United States)

    Gotlib, Dariusz; Gnat, Miłosz

    2013-12-01

    For many years, cartographers are involved in designing GIS and navigation systems. Most GIS applications use the outdoor data. Increasingly, similar applications are used inside buildings. Therefore it is important to find the proper model of indoor spatial database. The development of indoor navigation systems should utilize advanced teleinformation, geoinformatics, geodetic and cartographical knowledge. The authors present the fundamental requirements for the indoor data model for navigation purposes. Presenting some of the solutions adopted in the world they emphasize that navigation applications require specific data to present the navigation routes in the right way. There is presented original solution for indoor data model created by authors on the basis of BISDM model. Its purpose is to expand the opportunities for use in indoor navigation.

  4. Autonomous Robot Navigation based on Visual Landmarks

    DEFF Research Database (Denmark)

    Livatino, Salvatore

    2005-01-01

    autonomous navigation and self-localization using automatically selected landmarks. The thesis investigates autonomous robot navigation and proposes a new method which benefits from the potential of the visual sensor to provide accuracy and reliability to the navigation process while relying on naturally...... update of the estimated robot position while the robot is moving. In order to make the system autonomous, both acquisition and observation of landmarks have to be carried out automatically. The thesis consequently proposes a method for learning and navigation of a working environment and it explores......The use of landmarks for robot navigation is a popular alternative to having a geometrical model of the environment through which to navigate and monitor self-localization. If the landmarks are defined as special visual structures already in the environment then we have the possibility of fully...

  5. INS/CNS/GNSS integrated navigation technology

    CERN Document Server

    Quan, Wei; Gong, Xiaolin; Fang, Jiancheng

    2015-01-01

    This book not only introduces the principles of INS, CNS and GNSS, the related filters and semi-physical simulation, but also systematically discusses the key technologies needed for integrated navigations of INS/GNSS, INS/CNS, and INS/CNS/GNSS, respectively. INS/CNS/GNSS integrated navigation technology has established itself as an effective tool for precise positioning navigation, which can make full use of the complementary characteristics of different navigation sub-systems and greatly improve the accuracy and reliability of the integrated navigation system. The book offers a valuable reference guide for graduate students, engineers and researchers in the fields of navigation and its control. Dr. Wei Quan, Dr. Jianli Li, Dr. Xiaolin Gong and Dr. Jiancheng Fang are all researchers at the Beijing University of Aeronautics and Astronautics.

  6. Indoor inertial waypoint navigation for the blind.

    Science.gov (United States)

    Riehle, Timothy H; Anderson, Shane M; Lichter, Patrick A; Whalen, William E; Giudice, Nicholas A

    2013-01-01

    Indoor navigation technology is needed to support seamless mobility for the visually impaired. This paper describes the construction and evaluation of an inertial dead reckoning navigation system that provides real-time auditory guidance along mapped routes. Inertial dead reckoning is a navigation technique coupling step counting together with heading estimation to compute changes in position at each step. The research described here outlines the development and evaluation of a novel navigation system that utilizes information from the mapped route to limit the problematic error accumulation inherent in traditional dead reckoning approaches. The prototype system consists of a wireless inertial sensor unit, placed at the users' hip, which streams readings to a smartphone processing a navigation algorithm. Pilot human trials were conducted assessing system efficacy by studying route-following performance with blind and sighted subjects using the navigation system with real-time guidance, versus offline verbal directions. PMID:24110904

  7. [Laser navigation guided cleft lip repair].

    Science.gov (United States)

    Bing, Shi

    2016-06-01

    A new method using the ideal mid-facial line as the navigating reference was introduced to improve the outcome of cleft lip repair. Using the verticle coordinate crossing the middle point of the intercanthus line, surgeons could observe and correct the distortion of the fine structures in labial-nasal area. This laser projecting mid-facial-line navigation was repeatable, while not interfere the operating. In conclusion, generalizing laser navigation is a valuable supplementary for cleft lip repair. PMID:27526442

  8. Konzeption und Implementierung eines Quellcode-Navigators

    OpenAIRE

    Lu, Leiqin

    2004-01-01

    The Bauhaus project supports program understanding on both architectural level and source code level, which requires a graphical user interface tool for source code navigation. In this thesis a source code navigator is designed and implemented as part of the Bauhaus toolkit. The source code navigator cooperates with other tools in the Bauhaus toolkit. In particular, it is fully integrated with Gravis, the tool for architectural view, to provide an integrated environment for program unders...

  9. Global navigation satellite systems and their applications

    CERN Document Server

    Madry, Scott

    2015-01-01

    Dr. Madry, one of the world's leading experts in the field, provides in a condensed form a quick yet comprehensive overview of satellite navigation. This book concisely addresses the latest technology, the applications, the regulatory issues, and the strategic implications of satellite navigation systems. This assesses the strengths and weaknesses of satellite navigation networks and review of all the various national systems now being deployed and the motivation behind the proliferation of these systems.

  10. Research on integrated navigation method for AUV

    Institute of Scientific and Technical Information of China (English)

    GUO Zhen; SUN Feng

    2005-01-01

    The principles of the SINS/DVL integrated navigation system are introduced, and the compass status accuracy is compared. When the heading is changed, the dead reckoning algorithm using the heading information of the SINS (Strapdown inertial navigation systems) and DVL (doppler velocity log) is adopted to substitute the SINS/DVL integrated system. The simulation results show that the method can improve the accuracy of integrated navigation system when AUV (autonomous underwater vehicle) is in motion.

  11. Memory consolidation of landmarks in good navigators.

    Science.gov (United States)

    Janzen, Gabriele; Jansen, Clemens; van Turennout, Miranda

    2008-01-01

    Landmarks play an important role in successful navigation. To successfully find your way around an environment, navigationally relevant information needs to be stored and become available at later moments in time. Evidence from functional magnetic resonance imaging (fMRI) studies shows that the human parahippocampal gyrus encodes the navigational relevance of landmarks. In the present event-related fMRI experiment, we investigated memory consolidation of navigationally relevant landmarks in the medial temporal lobe after route learning. Sixteen right-handed volunteers viewed two film sequences through a virtual museum with objects placed at locations relevant (decision points) or irrelevant (nondecision points) for navigation. To investigate consolidation effects, one film sequence was seen in the evening before scanning, the other one was seen the following morning, directly before scanning. Event-related fMRI data were acquired during an object recognition task. Participants decided whether they had seen the objects in the previously shown films. After scanning, participants answered standardized questions about their navigational skills, and were divided into groups of good and bad navigators, based on their scores. An effect of memory consolidation was obtained in the hippocampus: Objects that were seen the evening before scanning (remote objects) elicited more activity than objects seen directly before scanning (recent objects). This increase in activity in bilateral hippocampus for remote objects was observed in good navigators only. In addition, a spatial-specific effect of memory consolidation for navigationally relevant objects was observed in the parahippocampal gyrus. Remote decision point objects induced increased activity as compared with recent decision point objects, again in good navigators only. The results provide initial evidence for a connection between memory consolidation and navigational ability that can provide a basis for successful

  12. Robotics_MobileRobot Navigation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Robots and rovers exploring planets need to autonomously navigate to specified locations. Advanced Scientific Concepts, Inc. (ASC) and the University of Minnesota...

  13. Lunar Autonomous Automatic Surface Navigation System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — To address the NASA GRC Laboratory need for navigation capabilities to provide location awareness, precision position fixing, best heading, and traverse path...

  14. Navigation and Ancillary Information Facility's SPICE

    Data.gov (United States)

    National Aeronautics and Space Administration — The Navigation and Ancillary Information Facility (NAIF), acting under the directions of NASA's Planetary Science Division, has built an information system named...

  15. Hybrid Guidance System for Relative Navigation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Future NASA architectures and missions will involve many distributed platforms that must work together. This in turn requires guidance, navigation and control...

  16. Age-dependence and intersubject variability of tracheobronchial particle clearance

    Directory of Open Access Journals (Sweden)

    Robert Sturm

    2011-01-01

    Full Text Available SUMMARY.Background: The detailed study of tracheobronchial clearanceof inhaled particles represents one of the basic research questionsin lung medicine. The clearance efficiency varies in different agegroups and between males and females.The differences can bepartly clarified by the application of a well validated theoreticalapproach. This study applied a relevant model to children (1 year,5 years, 10 years, juveniles (15 years, and adults of different ages(18, 21, 25, 34, 50, and 60 years and to both sexes. Methods: Themathematical model used for clearance simulation is based on theconcept of a stochastic lung structure and considers both early fastmucociliary clearance and a later, slow clearance fraction, fs, effectedby particular uptake by tracheobronchial cells, e.g., macrophagesand epithelial cells. According to this model, the calculated mucusvelocities for each airway generation of the tracheobronchial compartmentare normalized to a respective tracheal mucus velocitythat is estimated for each of the age groups studied from an allometricfunction. Results: In general, tracheobronchial clearanceefficiency undergoes a significant increase from childhood to youngadulthood, reaching a maximum at 25-30 years and decreasingagain from about 30 years to 60 years. Conversely to the improvementof clearance, the continuous change of airway morphometrywith increasing age causes a decrease of the filtering effect in thetrachea and main bronchi, which is of marked importance in infants.The modelling results demonstrate differences in tracheobronchialclearance between males and females, generally in the range from0 to 5%, which are exclusively determined by the individual lunggeometry. Conclusions: Based on theoretical computations itcan be concluded that tracheobronchial clearance is a phenomenonthat depends on both age and sex. Biological studies are necessaryto determine the cellular and molecular mechanisms underlyingthe age-dependent development of

  17. Autonomous integrated navigation method based on the strapdown inertial navigation system and Lidar

    Science.gov (United States)

    Zhang, Xiaoyue; Lin, Zhili; Zhang, Chunxi

    2014-07-01

    An integrated navigation method based on the strapdown inertial navigation system (SINS) and Doppler Lidar was presented and its validity is demonstrated by practical experiments. A very effective and independent integrated navigation mode is realized that both an inertial navigation system (INS) and Lidar are not interfered with or screened by electromagnetic waves. In our work, the SINS error model was first introduced, and the velocity error model was transformed into body reference coordinates. Then the expression for measurement model of SINS/Lidar integrated navigation was deduced under Lidar reference coordinates. For application of land or vehicle navigation, the expression for the measurement model was simplified, and observation analysis was carried out. Finally, numerical simulation and vehicle test results were carried out to validate the availability and utility of the proposed SINS/Lidar integrated navigation method for land navigation.

  18. Autonomous navigation system and method

    Science.gov (United States)

    Bruemmer, David J. [Idaho Falls, ID; Few, Douglas A. [Idaho Falls, ID

    2009-09-08

    A robot platform includes perceptors, locomotors, and a system controller, which executes instructions for autonomously navigating a robot. The instructions repeat, on each iteration through an event timing loop, the acts of defining an event horizon based on the robot's current velocity, detecting a range to obstacles around the robot, testing for an event horizon intrusion by determining if any range to the obstacles is within the event horizon, and adjusting rotational and translational velocity of the robot accordingly. If the event horizon intrusion occurs, rotational velocity is modified by a proportion of the current rotational velocity reduced by a proportion of the range to the nearest obstacle and translational velocity is modified by a proportion of the range to the nearest obstacle. If no event horizon intrusion occurs, translational velocity is set as a ratio of a speed factor relative to a maximum speed.

  19. Chemical compass for bird navigation

    DEFF Research Database (Denmark)

    Solov'yov, Ilia; Hore, Peter J.; Ritz, Thorsten;

    2014-01-01

    Migratory birds travel spectacular distances each year, navigating and orienting by a variety of means, most of which are poorly understood. Among them is a remarkable ability to perceive the intensity and direction of the Earth's magnetic field. Biologically credible mechanisms for the detection...... other relies on the quantum spin dynamics of transient photoinduced radical pairs. Originally suggested by Schulten in 1978 as the basis of the avian magnetic compass sensor, this mechanism gained support from the subsequent observation that the compass is light-dependent. The radical pair hypothesis...... began to attract increased interest following the proposal in 2000 that free radical chemistry could occur in the bird's retina initiated by photoexcitation of cryptochrome, a specialized photoreceptor protein. In the present paper we review the important physical and chemical constraints on a possible...

  20. TARGET RELATIVE NAVIGATION PERFORMANCE RESULTS FROM SINPLEX: A MINIATURIZED NAVIGATION SYSTEM

    OpenAIRE

    Steffes, Stephen; Theil, Stephan; Dumke, Michael; Heise, David; Krüger, Hans; Sagliano, Marco; Samaan, Malak; Oosterling, Han; Boslooper, Erik; Duivenvoorde, Tom; Schulte, Jan; Söderholm, S.; Skaborn, Daniel; Yanson, Yuriy; Esposito, Marco

    2014-01-01

    The goal of the SINPLEX project is to develop an innovative solution to significantly reduce the mass of the navigation subsystem for exploration missions which include landing and/or rendezvous and capture phases. The system mass is reduced by functionally integrating the navigation sensors, using micro- and nanotechnology to miniaturize electronics and fusing the sensor data within a navigation filter to improve navigation performance. A breadboard system was built and includes ...

  1. Approaches towards establishing of clearance levels in Japan

    International Nuclear Information System (INIS)

    It is important to establish necessary regulatory systems for decommissioning waste management, especially to establish clearance levels from regulatory control. To establish the regulatory systems, the Nuclear Safety Commission (NSC) has been discussing the unconditional clearance levels for materials from nuclear reactors since May 1997. The NSC tries to derive unconditional clearance levels for the materials such as concrete and ferrous metal, arising from nuclear reactor decommissioning. In the derivation, both disposal and recycle/reuse of the materials are considered. Typical scenarios and parameter values for dose estimation are selected considering the Japanese natural and social conditions. Preliminary clearance levels were derived from 10 μSv/yr of individual dose criterion and deterministic analysis. For most radionuclides, the preliminary results are the same order of magnitude recommended in IAEA-TECDOC-855. Some radionuclides such as β emitters, however, are different order of magnitude from those recommended in IAEA-TECDOC-855. It is necessary that international organizations lead the discussions on the clearance levels to conclude final consensus. (author)

  2. Relevant aspects in the application of exemption and clearance criteria

    International Nuclear Information System (INIS)

    Full text: Nowadays the relevant question in the Radiological Protection is the necessity of the establishment of criteria to remove materials (scrap) from the regulatory control. In 1996, the International Atomic energy Agency -IAEA published the International Basic Safety Standards for Protection Against Ionizing Radiation and for the Safety of Radiation Sources- the BSS-115, which establishes the requirements for exclusion, exemption and clearance for practices, sources, materials and pieces. The BSS's criteria were established in terms of effective dose and the collective effective dose committed expected to be incurred by any member of the public due to practices or sources that will be free from regulatory control (exemption) or a material that will be removed from authorized practices (clearance). In order to become easy to implement these criteria, in the Schedule I of BSS were established exemption levels specified in activity concentration or activity for several radionuclides. These levels that would give rise to doses to appropriate critical groups that correspond to the dose criteria for the exemption of practices. In Brazil the regulatory authority, Comissao Nacional de Energia Nuclear - CNEN, published in 2005 The Basic Guidelines for Radiological Protection, the CNEN-NN-3.01, incorporating BSS's concepts and criteria for exemption and clearance. However, in the practical implementations of this guidelines during the practices licensing and inspections activities were verified the necessity of clearance criteria in terms of superficial activity, for become accomplishable to implement the monitoring process of pieces and materials (scrap) before remove that from regulatory control (clearance). (author)

  3. Radioactive Aerosols in the Clinical Study of Pulmonary Clearance

    International Nuclear Information System (INIS)

    The study of pulmonary clearance mechanisms has acquired particular importance owing to the growing pollution of the environment and to the increasing incidence and seriousness of cases of pneumoconiosis. Such research is particularly important in radiopathology because of the frequent occurrence of respiratory radioactive contamination. The authors' aim is to tackle this problem and in particular to study long-term clearance mechanisms. Before starting this work, however, they propose to determine the contamination parameters as accurately as possible. For this purpose they plan to study respiratory function in normal subjects by administering labelled aerosols with well-defined physico-chemical characteristics; the first stage of the investigation is then to observe the kinetics of fixation and clearance in the short term. They describe the installations used for this voluntary contamination which must provide a means of producing the aerosols and administering them in controlled amounts and must also ensure efficient protection of the operators against irradiation arid contamination. The choice of the aerosols is also discussed: this is governed mainly by the nature of the vectors, the particle size and the physical characteristics of the tracers. Finally, the authors outline the detection and measuring techniques which they are using to study contamination kinetics, evaluate contamination burdens and follow the short-term clearance. These data constitute a preliminary basis for the study of long-term clearance. (author)

  4. ELMO1 signaling in apoptotic germ cell clearance and spermatogenesis.

    Science.gov (United States)

    Elliott, Michael R; Ravichandran, Kodi S

    2010-10-01

    Apoptosis and the subsequent removal of dying cells are crucial processes for tissue development and maintenance. Although we are beginning to understand the signaling pathways that control the phagocytic clearance of apoptotic cells, the physiological relevance of these pathways is lacking. During spermatogenesis, over half of the developing germ cells eventually die by apoptosis, yet the signaling pathways that regulate the phagocytic clearance of these dying cells or the impact of this clearance on development and maintenance of the germ cell population is not well understood. The ELMO1/Dock180 proteins form an evolutionarily conserved signaling module that functions as a bipartite guanine nucleotide exchange factor for the small GTPase Rac. The subsequent Rac-dependent cytoskeletal changes play an important role in the physical engulfment of apoptotic cells. Recent findings demonstrate an in vivo role for ELMO1-dependent clearance in the testes, with implications for spermatogenesis. Here we will discuss the role of apoptotic cell clearance during spermatogenesis, with a particular emphasis on ELMO1/Dock180 signaling. PMID:20958313

  5. Waypoint navigation with a vibrotactile waist belt

    NARCIS (Netherlands)

    Erp, J.B.F. van; Veen, H.A.H.C. van; Jansen, C.; Dobbins, T.

    2005-01-01

    Presenting waypoint navigation on a visual display is not suited for all situations. The present experiments investigate if it is feasible to present the navigation information on a tactile display. Important design issue of the display is how direction and distance information must be coded. Import

  6. Blavigator: a navigation aid for blind persons

    OpenAIRE

    José, João; MORENO, M; Pinilla-Dutoit, J.; Rodrigues, J. M. F.; du Buf, J. M. H.

    2012-01-01

    Blavigator (blind navigator) is a vision aid for blind and visuaIIy impaired persons. It supports local navigation by detecting waIkable paths in the immediate vicinity of the user. It guides the user for centering on the path.

  7. Rosetta Star Tracker and Navigation Camera

    DEFF Research Database (Denmark)

    Thuesen, Gøsta

    1998-01-01

    Proposal in response to the Invitation to Tender (ITT) issued by Matra Marconi Space (MSS) for the procurement of the ROSETTA Star Tracker and Navigation Camera.......Proposal in response to the Invitation to Tender (ITT) issued by Matra Marconi Space (MSS) for the procurement of the ROSETTA Star Tracker and Navigation Camera....

  8. Understanding the Social Navigation User Experience

    Science.gov (United States)

    Goecks, Jeremy

    2009-01-01

    A social navigation system collects data from its users--its community--about what they are doing, their opinions, and their decisions, aggregates this data, and provides the aggregated data--community data--back to individuals so that they can use it to guide behavior and decisions. Social navigation systems empower users with the ability to…

  9. Validation of principles for tactile navigation displays

    NARCIS (Netherlands)

    Erp, J.B.F. van; Werkhoven, P.J.

    2006-01-01

    Access to navigation information rapidly becomes standard in many situations, for example through GPS receivers and collision avoidance systems in cars. However, perceiving and processing the information may result in overloading the userÆs visual sense and cognitive resources. Intuitive navigation

  10. Evolved Navigation Theory and Horizontal Visual Illusions

    Science.gov (United States)

    Jackson, Russell E.; Willey, Chela R.

    2011-01-01

    Environmental perception is prerequisite to most vertebrate behavior and its modern investigation initiated the founding of experimental psychology. Navigation costs may affect environmental perception, such as overestimating distances while encumbered (Solomon, 1949). However, little is known about how this occurs in real-world navigation or how…

  11. Enhancing Navigation on Wikipedia with Social Tags

    CERN Document Server

    Zubiaga, Arkaitz

    2012-01-01

    Social tagging has become an interesting approach to improve search and navigation over the actual Web, since it aggregates the tags added by different users to the same resource in a collaborative way. This way, it results in a list of weighted tags describing its resource. Combined to a classical taxonomic classification system such as that by Wikipedia, social tags can enhance document navigation and search. On the one hand, social tags suggest alternative navigation ways, including pivot-browsing, popularity-driven navigation, and filtering. On the other hand, it provides new metadata, sometimes uncovered by documents' content, that can substantially improve document search. In this work, the inclusion of an interface to add user-defined tags describing Wikipedia articles is proposed, as a way to improve article navigation and retrieval. As a result, a prototype on applying tags over Wikipedia is proposed in order to evaluate its effectiveness.

  12. GPS-based navigation for space applications

    Science.gov (United States)

    Champetier, C.; Duhamel, T.; Frezet, M.

    1995-03-01

    We present in this paper a survey of the applications of the GPS (global positioning system) system for spacecraft navigation. The use of the GPS techniques for space missions is a striking example of dual-use of military technology; it can bring vast improvements in performances and, in some cases, for a reduced cost. We only deal in this paper with the functional aspects and performances of GPS uses without addressing the issues of hardware implementation where current developments are leading to an increased miniaturization of the GPS receiver hardware. We start this paper with a general overview of the GPS system and its various uses for space missions. We then focus on four areas where MATRA MARCONI Space has conducted detailed analyses of performances: autonomous navigation for geostationary spacecraft, relative navigation for space rendezvous, differential navigation for landing vehicles, absolute navigation for launchers and reentry vehicles.

  13. Navigation aided surgery for facial fractures

    International Nuclear Information System (INIS)

    A navigation system that has been developed in neurosurgery has recently been applied in the maxillofacial region. We introduced a navigation system (Stealth Station, Medtronic) in the maxillofacial region. As preoperative preparation, CT scanning was performed with a slice of 1 mm. Navigation aided surgery was performed in 11 patients with facial fractures between April 2005 and July 2006. Navigation aided reduction of the bone segment was performed by comparing with the sound site on the screen. Facial symmetry was recovered in 10 of 11 cases. Facial asymmetry in 1 case (midfacial multiple fractures) remained, because the system did not work after the surgeon contacted the reference frame during the operation. The navigation system is useful for repairing facial fractures, especially for verifying facial symmetry. (author)

  14. Risk management model of winter navigation operations.

    Science.gov (United States)

    Valdez Banda, Osiris A; Goerlandt, Floris; Kuzmin, Vladimir; Kujala, Pentti; Montewka, Jakub

    2016-07-15

    The wintertime maritime traffic operations in the Gulf of Finland are managed through the Finnish-Swedish Winter Navigation System. This establishes the requirements and limitations for the vessels navigating when ice covers this area. During winter navigation in the Gulf of Finland, the largest risk stems from accidental ship collisions which may also trigger oil spills. In this article, a model for managing the risk of winter navigation operations is presented. The model analyses the probability of oil spills derived from collisions involving oil tanker vessels and other vessel types. The model structure is based on the steps provided in the Formal Safety Assessment (FSA) by the International Maritime Organization (IMO) and adapted into a Bayesian Network model. The results indicate that ship independent navigation and convoys are the operations with higher probability of oil spills. Minor spills are most probable, while major oil spills found very unlikely but possible. PMID:27207023

  15. Periodic response of multi-disk rotors with bearing clearances

    Science.gov (United States)

    Kim, Y. B.; Noah, S. T.; Choi, Y. S.

    1991-02-01

    The forced steady state response of a multi-disk rotor system involving a clearance at one of the bearings is determined by using a harmonic balance approach. The impedance method is applied to each of the harmonic steady state components in order to reduce the system to its displacement at the non-linear bearing support. The results reveal the interrelated roles of the bearing clearance, mass eccentricity and side force in producing dangerous subharmonics. The significant effects of the strong non-linearity of a bearing clearance are studied as related to the various system parameters. The results show that the approach developed in this study is computationally superior to numerical integration methods in analyzing multi-disk rotor systems with strong non-linearity.

  16. Bromosulphophthalein clearance rates in sheep with pyrrolizidine liver damage.

    Science.gov (United States)

    Lanigan, G W; Peterson, J E

    1979-05-01

    Sheep fed a ration containing 50% of dried Heliotropium europaeum showed a marked decline in bromosulphophthalein (BSP) fractional clearance rate during the first 3 months feeding. Thereafter, the response of individual animals varied widely on a time basis, although 3 groups could be identified. In the terminal stages, mean clearance rates were below 20% of initial values, with some sheep showing a decline in excess of 90%. Loss of liver functional capacity was generally much greater than indicated by the degree of damage revealed by histopathology. Thus, a suitably modified test could have considerable prognostic value in the field. In this investigation, all sheep with clearance rates below 0.15 died when exposed to a further period of H. europaeum feeding. PMID:475677

  17. Ineffective airway clearance in children with acute respiratory infection

    Directory of Open Access Journals (Sweden)

    Lívia Zulmyra Cintra Andrade

    2014-03-01

    Full Text Available This cross-sectional study was performed with 151 children inpatients of a pediatric hospital in Northeastern Brazil, with the objective to analyze the accuracy of the defining characteristics of the diagnoses ineffective airway clearance in children with acute respiratory infection. A thorough respiratory evaluation was performed and the diagnostic inference was developed by specialists. The most frequent defining characteristics were adventitious breath sounds, ineffective cough, dyspnea, and changes in respiratory rate. Ineffective airway clearance was present in 37.7% of the sample. Agitation was the characteristic with the highest sensitivity. Dyspnea, adventitious breath sounds, orthopnea, changes in respiratory rate and agitation presented higher specificity for the diagnosis. In conclusion, the defining characteristics showed different performances to correctly classify children with infective airway clearance. Studies like this can contribute for a correct nursing diagnostic inference and for the implementation of more effective interventions, thus improving the quality of health care. Descriptors: Respiratory Tract Infections; Nursing Diagnosis; Child.

  18. Pharmacometabonomic Prediction of Busulfan Clearance in Hematopoetic Cell Transplant Recipients.

    Science.gov (United States)

    Navarro, Sandi L; Randolph, Timothy W; Shireman, Laura M; Raftery, Daniel; McCune, Jeannine S

    2016-08-01

    Intravenous (IV) busulfan doses are often personalized to a concentration at steady state (Css) using the patient's clearance, which is estimated with therapeutic drug monitoring. We sought to identify biomarkers of IV busulfan clearance using a targeted pharmacometabonomics approach. A total of 200 metabolites were quantitated in 106 plasma samples, each obtained before IV busulfan administration in hematopoietic cell transplant (HCT) recipients. Both univariate linear regression with false discovery rate (FDR) and pathway enrichment analyses using the Global test were performed. In the univariate analysis, glycine, N-acetylglycine, 2-hydroxyisovaleric acid, creatine, serine, and tyrosine were statistically significantly associated with IV busulfan clearance at P 0.1. Glycine is a component of glutathione, which is conjugated with busulfan via glutathione transferase enzymes. These results demonstrate the potential utility of pharmacometabonomics to inform IV busulfan dosing. Future studies are required to validate these findings. PMID:27350098

  19. Progress with volunteer studies of nasal deposition and clearance

    International Nuclear Information System (INIS)

    Inhalation is the main route of intake of radioactive material for workers, and can be an important pathway for members of the public following accidental releases of radioactivity to the environment. Much of the inhaled radioactivity initially deposits in the nose, typically over 40% for particles of aerodynamic diameter (dae) greater than 2 μm. However, there is remarkably little information on the clearance from the human nose of particles deposited during inhalation and, until now, none on the clearance of the significant fraction of material that remains in the nasal passage for more than 12 hours. NRPB is conducting a volunteer study to determine the effects of particle size and breathing pattern on particle deposition in, and clearance from, the human nasal passage. This article summarises results obtained to date. (author)

  20. New bionic navigation algorithm based on the visual navigation mechanism of bees

    Science.gov (United States)

    Huang, Yufeng; Liu, Yi; Liu, Jianguo

    2015-04-01

    Through some research on visual navigation mechanisms of flying insects especially honeybees, a novel navigation algorithm integrating entropy flow with Kalman filter has been introduced in this paper. Concepts of entropy image and entropy flow are also introduced, which can characterize topographic features and measure changes of the image respectively. To characterize texture feature and spatial distribution of an image, a new concept of contrast entropy image has been presented in this paper. Applying the contrast entropy image to the navigation algorithm to test its' performance of navigation and comparing with simulation results of intensity entropy image, a conclusion that contrast entropy image performs better and more robust in navigation has been made.

  1. Effect of Internal Clearance on Load Distribution and Life of Radially Loaded Ball and Roller Bearings

    Science.gov (United States)

    Oswald, Fred B.; Zaretsky, Erwin V.; Poplawski, Joseph V.

    2012-01-01

    The effect of internal clearance on radially loaded deepgroove ball and cylindrical roller bearing load distribution and fatigue life was determined for four clearance groups defined in the bearing standards. The analysis was extended to negative clearance (interference) conditions to produce a curve of life factor versus internal clearance. Rolling-element loads can be optimized and bearing life maximized for a small negative operating clearance. Life declines gradually with positive clearance and rapidly with increasing negative clearance. Relationships were found between bearing life and internal clearance as a function of ball or roller diameter, adjusted for load. Results are presented as life factors for radially loaded bearings independent of bearing size or applied load. In addition, a modified Stribeck Equation is presented that relates the maximum rolling-element load to internal bearing clearance.

  2. Nuclear security. DOE actions to improve the personnel clearance program

    International Nuclear Information System (INIS)

    The status of the Department of Energy's (DOE) implementation of recommendations in our two reports on DOE's personnel security clearance program was determined. The recommendations were aimed at improving the timeliness, accuracy, and efficiency of personnel security clearance decisions. Specifically, the objective was to determine and report on steps DOE is taking to implement these recommendations. In summary, it was found that DOE has either initiated action or is studying ways to address all the recommendations, but none of the recommendations have been completely implemented. The effectiveness of the DOE actions will depend, in part, on the adequacy of its internal control system for overseeing and evaluating program operations. DOE's personnel security clearance program is intended to provide reasonable assurance that personnel with access to classified information and materials are trustworthy. The Department requests that the Office of Personnel Management or the Federal Bureau of Investigation collect personal data on each person who requires such access to do his or her job. Based on these background investigations, DOE officials authorize individuals whose personal histories indicate that they are trustworthy to have access to classified information, secured facilities, and controlled materials as needed to perform their jobs. DOE has five types of these authorizations or personnel security clearances and must update information on personnel holding each type at 5-year intervals to confirm their continuing reliability. The five types are based on the types of security interests to which the person needs access, e.g., persons needing nuclear weapons-related data must have a Q clearance, and persons with a top secret clearance can have access to national security data classified as top secret

  3. Mucociliary clearance, airway inflammation and nasal symptoms in urban motorcyclists

    Directory of Open Access Journals (Sweden)

    Tereza C.S. Brant

    2014-01-01

    Full Text Available OBJECTIVES: There is evidence that outdoor workers exposed to high levels of air pollution exhibit airway inflammation and increased airway symptoms. We hypothesized that these workers would experience increased airway symptoms and decreased nasal mucociliary clearance associated with their exposure to air pollution. METHODS: In total, 25 non-smoking commercial motorcyclists, aged 18-44 years, were included in this study. These drivers work 8-12 hours per day, 5 days per week, driving on urban streets. Nasal mucociliary clearance was measured by the saccharine transit test; airway acidification was measured by assessing the pH of exhaled breath condensate; and airway symptoms were measured by the Sino-nasal Outcome Test-20 questionnaire. To assess personal air pollution exposure, the subjects used a passive-diffusion nitrogen dioxide (NO2 concentration-monitoring system during the 14 days before each assessment. The associations between NO2 and the airway outcomes were analyzed using the Mann-Whitney test and the Chi-Square test. Clinicaltrials.gov: NCT01976039. RESULTS: Compared with clearance in healthy adult males, mucociliary clearance was decreased in 32% of the motorcyclists. Additionally, 64% of the motorcyclists had airway acidification and 92% experienced airway symptoms. The median personal NO2 exposure level was 75 mg/m3 for these subjects and a significant association was observed between NO2 and impaired mucociliary clearance (p = 0.036. CONCLUSION: Non-smoking commercial motorcyclists exhibit increased airway symptoms and airway acidification as well as decreased nasal mucociliary clearance, all of which are significantly associated with the amount of exposure to air pollution.

  4. The influence of body posture on lithium clearance

    DEFF Research Database (Denmark)

    Kamper, A L; Strandgaard, S; Holstein-Rathlou, N H;

    1988-01-01

    fall in the sitting position, and fell significantly to 26 +/- 5 ml/min (p less than 0.025) in walking subjects. Absolute proximal tubular reabsorption rate of fluid correspondingly rose from 83 +/- 16 to 92 +/- 15 ml/min (p less than 0.005) and sodium clearance fell from 1.52 +/- 0.81 to 1.00 +/- 0...... during moderate physical activity. Hence, when renal tubular function is studied with the lithium clearance method, standardization of posture and physical activity is important. In such studies physical activity such as walking should particularly be avoided....

  5. The influence of body posture on lithium clearance

    DEFF Research Database (Denmark)

    Kamper, A L; Strandgaard, S; Holstein-Rathlou, N H; Munck, O; Leyssac, P P

    1988-01-01

    measured four times at 1-week intervals: two in the supine and one in the sitting position, and one when the subject was walking around. Glomerular filtration rate was not influenced by posture changes. On the contrary, lithium clearance, which in the supine position was 30 +/- 9 ml/min (1 SD), tended to...... during moderate physical activity. Hence, when renal tubular function is studied with the lithium clearance method, standardization of posture and physical activity is important. In such studies physical activity such as walking should particularly be avoided....

  6. Venous catheterization with ultrasound navigation

    Energy Technology Data Exchange (ETDEWEB)

    Kasatkin, A. A., E-mail: ant-kasatkin@yandex.ru; Nigmatullina, A. R. [Izhevsk State Medical Academy, Kommunarov street, 281, Izhevsk, Russia, 426034 (Russian Federation); Urakov, A. L., E-mail: ant-kasatkin@yandex.ru [Institute of Mechanics Ural Branch of Russian Academy of Sciences, T.Baramzinoy street 34, Izhevsk, Russia, 426067, Izhevsk (Russian Federation); Izhevsk State Medical Academy, Kommunarov street, 281, Izhevsk, Russia, 426034 (Russian Federation)

    2015-11-17

    By ultrasound scanning it was determined that respiratory movements made by chest of healthy and sick person are accompanied by respiratory chest rise of internal jugular veins. During the exhalation of an individual diameter of his veins increases and during the breath it decreases down to the complete disappearing if their lumen. Change of the diameter of internal jugular veins in different phases can influence significantly the results of vein puncture and cauterization in patients. The purpose of this research is development of the method increasing the efficiency and safety of cannulation of internal jugular veins by the ultrasound visualization. We suggested the method of catheterization of internal jugular veins by the ultrasound navigation during the execution of which the puncture of venous wall by puncture needle and the following conduction of J-guide is carried out at the moment of patient’s exhalation. This method decreases the risk of complications development during catheterization of internal jugular vein due to exclusion of perforating wound of vein and subjacent tissues and anatomical structures.

  7. Inertial sensors for smartphones navigation.

    Science.gov (United States)

    Dabove, P; Ghinamo, G; Lingua, A M

    2015-01-01

    The advent of smartphones and tablets, means that we can constantly get information on our current geographical location. These devices include not only GPS/GNSS chipsets but also mass-market inertial platforms that can be used to plan activities, share locations on social networks, and also to perform positioning in indoor and outdoor scenarios. This paper shows the performance of smartphones and their inertial sensors in terms of gaining information about the user's current geographical locatio n considering an indoor navigation scenario. Tests were carried out to determine the accuracy and precision obtainable with internal and external sensors. In terms of the attitude and drift estimation with an updating interval equal to 1 s, 2D accuracies of about 15 cm were obtained with the images. Residual benefits were also obtained, however, for large intervals, e.g. 2 and 5 s, where the accuracies decreased to 50 cm and 2.2 m, respectively. PMID:26753121

  8. Venous catheterization with ultrasound navigation

    Science.gov (United States)

    Kasatkin, A. A.; Urakov, A. L.; Nigmatullina, A. R.

    2015-11-01

    By ultrasound scanning it was determined that respiratory movements made by chest of healthy and sick person are accompanied by respiratory chest rise of internal jugular veins. During the exhalation of an individual diameter of his veins increases and during the breath it decreases down to the complete disappearing if their lumen. Change of the diameter of internal jugular veins in different phases can influence significantly the results of vein puncture and cauterization in patients. The purpose of this research is development of the method increasing the efficiency and safety of cannulation of internal jugular veins by the ultrasound visualization. We suggested the method of catheterization of internal jugular veins by the ultrasound navigation during the execution of which the puncture of venous wall by puncture needle and the following conduction of J-guide is carried out at the moment of patient's exhalation. This method decreases the risk of complications development during catheterization of internal jugular vein due to exclusion of perforating wound of vein and subjacent tissues and anatomical structures.

  9. Pulsar Navigation in the Solar System

    CERN Document Server

    Dong, Jiang

    2008-01-01

    The X-ray Pulsar-based Autonomous Navigation(XNAV) were recently tested which use the Crab pulsar (PSR B0531+21) in the USA Experiment on flown by the Navy on the Air Force Advanced Research and Global Observation Satellite (ARGOS) under the Space Test Program. It provide the way that the spacecraft could autonomously determine its position with respect to an inertial origin. Now I analysis the sensitivity of the exist instrument and the signal process to use radio pulsar navigation and discuss the integrated navigation use pulsar,then give the different navigation mission analysis and design process basically which include the space, the airborne, the ship and the land of the planet or the lunar.So the pulsar navigation can give the continuous position in deep spaces, that means we can freedom fly successfully in the solar system use celestial navigation that include pulsar and traditional star sensor.It also can less or abolish the depend of Global Navigation Satellite System which include GPS, GRONSS, Gali...

  10. Space optical navigation techniques: an overview

    Science.gov (United States)

    Rebordão, J. M.

    2013-11-01

    Optical or vision-based navigation is an enabling technology for satellite autonomous navigation associated to different navigation approaches such as cruising, fly-by, terrain relative navigation, landing, rendezvous and docking between spacecrafts, rigidity of multi-satellite constellations. Since 2001, in many different ESA projects, the author and his team (at INETI and currently at FCUL) have been associated to most of the developments of the optical components of autonomous navigation, in cooperation with space primes or GNC subsystems suppliers. A unique experience related to seemingly simple photonic concepts associated to computational vision, photonic noises, camera tradeoffs and system concepts has emerged, and deserves a synthesis especially because some of these concepts are being implemented in the ESA Proba 3 mission and ESA is currently updating the technology in view of forthcoming planetary missions to Jupiter, Jupiter moons and asteroids. It is important to note that the US have already flown several missions relying on autonomous navigation and that NASA experience is at least one decade old. System approaches, sources of difficulty, some tradeoffs in both (and between) hardware and software, critical interface issues between the imaging and GNC (Guidance, Navigation and Control) subsystems, image processing techniques, utilization of apriori or to be estimated information, uncertainties, simulation of the imaging chain and non-cooperative environments will be addressed synthetically for both passive (optical) and active (lidar) systems.

  11. Nuclear burst detection information transfers system based on BD Navigation

    International Nuclear Information System (INIS)

    The article introduces the character of BD Navigation System.The feasibility of using BD Navigation System is analyzed. Nuclear explosion information transmission system based on BD Navigation System is designed and implemented. (authors)

  12. Navigated minimally invasive unicompartmental knee arthroplasty.

    Science.gov (United States)

    Jenny, Jean-Yves; Müller, Peter E; Weyer, R; John, Michael; Weber, Patrick; Ciobanu, Eugène; Schmitz, Andreas; Bacher, Thomas; Neumann, Wolfram; Jansson, Volkmar

    2006-10-01

    Unicompartmental knee arthroplasty (UKA) is an alternative procedure to high tibial osteotomy. This study assessed the procedure using computer navigation to improve implantation accuracy and presents early radiological results of a group of patients implanted with the univation UKA (B. Braun Aesculap, Tuttlingen, Germany) with navigation instrumentation and a minimally invasive approach. The authors concluded that navigated implantation of a UKA using a nonimage-based system improved radiologic accuracy implantation without significant inconvenience and minimal change in the conventional operating technique. PMID:17407935

  13. Navigational Use of Cassini Delta V Telemetry

    Science.gov (United States)

    Roth, Duane C.; Antreasian, Peter G.; Ardalan, Shadan M.; Criddle, Kevin E.; Goodson, Troy; Ionasescu, Rodica; Jones, Jeremy B.; Parcher, Daniel W.; Pelletier, Frederic J.; Thompson, Paul F.; Vaughan, Andrew T.

    2008-01-01

    Telemetry data are used to improve navigation of the Saturn orbiting Cassini spacecraft. Thrust induced delta V's are computed on-board the spacecraft, recorded in telemetry, and downlinked to Earth. This paper discusses how and why the Cassini Navigation team utilizes spacecraft delta V telemetry. Operational changes making this information attractive to the Navigation Team will be briefly discussed, as will spacecraft hardware and software algorithms responsible for the on-board computation. An analysis of past delta V telemetry, providing calibrations and accuracies that can be applied to the estimation of future delta V activity, is described.

  14. INTERACTION SPECIFICITY IN AIR NAVIGATION COMMUNICATION

    Directory of Open Access Journals (Sweden)

    Kateryna Povoroznyk

    2012-09-01

    Full Text Available  The article is about a problem of air navigation communication and the positive influence of interpersonal communication for air navigation specialists. The ability of organizing a dialogue with subject – subject relationship substantially increase professional interaction efficiency. As scientific surveys show a dialogue is not just the form of communication, but an organizing phenomenon that directly influences the quality of air navigation communication, but there is still a gap in the aviation English teaching technics, mainly due to lack of psycho – pedagogical knowledge concerning human factor peculiarities within dialogical relationship framework. The article highlights the possible ways of the problem solution.

  15. Navigating nuclear science: Enhancing analysis through visualization

    Energy Technology Data Exchange (ETDEWEB)

    Irwin, N.H.; Berkel, J. van; Johnson, D.K.; Wylie, B.N.

    1997-09-01

    Data visualization is an emerging technology with high potential for addressing the information overload problem. This project extends the data visualization work of the Navigating Science project by coupling it with more traditional information retrieval methods. A citation-derived landscape was augmented with documents using a text-based similarity measure to show viability of extension into datasets where citation lists do not exist. Landscapes, showing hills where clusters of similar documents occur, can be navigated, manipulated and queried in this environment. The capabilities of this tool provide users with an intuitive explore-by-navigation method not currently available in today`s retrieval systems.

  16. Integration of Omega and satellite navigation systems

    Science.gov (United States)

    Schlachta, Henry B.

    An extensive series of laboratory tests and flight trials has established that the hybrid Omega/VLF/GPS system effectively applies GPS to the enhancement of Omega with a cost-effective operator installation. The accuracy enhancement thus achieved also increases the reliability of navigation and furnishes aviation fuel savings superior to those of Omega, as a result of reduced flight-path wavering. The prospective GPS/GLONASS navigation system currently undergoing definition will be the first certifiable as a sole means on navigation; the Omega/VLF/GPS hybrid can serve as a transitional system.

  17. The Principle and Application of Maser Navigation

    OpenAIRE

    Dong, Jiang

    2008-01-01

    The traditional celestial navigation system (CNS) is used the moon, stars, and planets as celestial guides. Then the star tracker (i.e. track one star or planet or angle between it) and star sensor (i.e. sense many star simultaneous) be used to determine the attitude of the spacecraft. Pulsar navigation also be introduced to CNS. Maser is another interested celestial in radio astronomy which has strong flux density as spectral line. Now we analysis the principle of maser navigation which base...

  18. Mucociliary and cough clearance as a biomarker for therapeutic development

    DEFF Research Database (Denmark)

    Bennett, William D; Daviskas, Evangelia; Hasani, Amir;

    2010-01-01

    A workshop/symposium on “Mucociliary and Cough Clearance (MCC/CC) as a Biomarker for Therapeutic Development” was held on October 21–22, 2008, in Research Triangle Park, NC, to discuss the methods for measurement of MCC/CC and how they may be optimized for assessing new therapies designed to...

  19. 75 FR 52798 - State-07, Cryptographic Clearance Records

    Science.gov (United States)

    2010-08-27

    ...: Unclassified. SYSTEM LOCATION: Department of State, 301 4th St., SW., Room 750 Washington, DC 20547. CATEGORIES... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE State-07, Cryptographic Clearance Records Summary: Notice is hereby given that the Department of State proposes to...

  20. Effect of lindane on the clearance rate of Daphnia magna

    NARCIS (Netherlands)

    Hartgers, E.M.; Heugens, E.W.; Deneer, J.W.

    1999-01-01

    The impact of the insecticide lindane (%-hexachlorocyclohexane) on the clearance rate (CR) of Daphnia magna was investigated using artificial beads. CR (24-h EC50: 65 7g Lm1) was found to be a more sensitive endpoint than acute lethality for D. magna (48-h LC50: 516 7g Lm1). The onset of the effect

  1. Modifications of lung clearance mechanisms by acute influenza A infection

    International Nuclear Information System (INIS)

    Four volunteers with naturally acquired, culture-proved influenza A infection inhaled a radiolabeled aerosol to permit investigation of lung mucociliary clearance mechanisms during and after symptomatic illness. Mucus transport in the trachea was undetectable when monitored with an external multidetector probe within 48 hours of the onset of the illness, but was found at a normal velocity by 1 week in three of the four subjects. In two volunteers who coughed 23 to 48 times during the 4.5-hour observation period, whole lung clearance was as fast within the first 48 hours of illness as during health 3 months later in spite of the absence of measurable tracheal mucus transport. Conversely, in spite of the return 1 week later of mucus transport at velocities expected in the trachea, whole lung clearance for the 4.5-hour period was slowed in two volunteers who coughed less than once an hour. The data offer evidence that cough is important in maintaining lung clearance for at least several days after symptomatic influenza A infection when other mechanisms that depend on ciliary function are severely deficient

  2. 14 CFR 93.311 - Minimum terrain clearance.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Minimum terrain clearance. 93.311 Section 93.311 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR TRAFFIC AND GENERAL OPERATING RULES SPECIAL AIR TRAFFIC RULES Special Flight Rules in the Vicinity of Grand Canyon National Park, AZ §...

  3. Decision Assessment of Clearance Level on Radioactive Waste Management

    International Nuclear Information System (INIS)

    Radioactive waste on the safe level activity containing very small radioactive material gives small radiology influence to the human, it is not necessary to control by regulatory body. The radioactive waste on the safe level activity is safe to release as the common waste. For exemption of the control, it is required the safe activity level limits in which the value of clearance level is fulfilled by regulatory body, however until now it is not decided yet. The exemption decision is obtained if its activity is lower than or same with clearance level based on the annual effective dose receiving by public on the value is lower than or same with 0,01 mSv. The exposure pathways of radioactive waste to the human have important role for determination of clearance level. The decision assessment of clearance level on the radioactive waste management has been done by analysis of radioactive exposure pathways to the human for activities of the disposal and the recycle of solid wastes, also the release of liquid and gas effluent. For solid waste disposal, the exposure pathway was evaluated since the transportation of packed waste from the treatment facility to the disposal facility and during its operation. Exposure pathways for solid waste recycle consist of the pathways for handling and transportation of cleared material to the recycling facility, the fabrication and the utilization of its product. Exposure pathways for liquid and gas releases occur since its releases to the environment up to the human (public) by specific traffic lane. (author)

  4. Mucociliary and cough clearance as a biomarker for therapeutic development

    DEFF Research Database (Denmark)

    Bennett, William D; Daviskas, Evangelia; Hasani, Amir;

    2010-01-01

    A workshop/symposium on “Mucociliary and Cough Clearance (MCC/CC) as a Biomarker for Therapeutic Development” was held on October 21–22, 2008, in Research Triangle Park, NC, to discuss the methods for measurement of MCC/CC and how they may be optimized for assessing new therapies designed to impr...

  5. Mucociliary clearance, airway inflammation and nasal symptoms in urban motorcyclists

    OpenAIRE

    Brant, Tereza C S; Yoshida, Carolina T; Tomas de S. Carvalho; Nicola, Marina L; Jocimar. A. Martins; Lays M. Braga; Regiani C. de Oliveira; Vilma Leyton; Carmen S. de André; Saldiva, Paulo H. N.; Rubin, Bruce K.; Naomi K. Nakagawa

    2014-01-01

    OBJECTIVES: There is evidence that outdoor workers exposed to high levels of air pollution exhibit airway inflammation and increased airway symptoms. We hypothesized that these workers would experience increased airway symptoms and decreased nasal mucociliary clearance associated with their exposure to air pollution. METHODS:...

  6. In Vivo Renal Clearance, Biodistribution, Toxicity of Gold nanoclusters

    CERN Document Server

    Zhang, Xiao-Dong; Shen, Xiu; Liu, Pei-Xun; Fan, Fei-Yue; Fan, Sai-Jun; 10.1016/j.biomaterials.2012.03.020

    2012-01-01

    Gold nanoparticles have shown great prospective in cancer diagnosis and therapy, but they can not be metabolized and prefer to accumulate in liver and spleen due to their large size. The gold nanoclusters with small size can penetrate kidney tissue and have promise to decrease in vivo toxicity by renal clearance. In this work, we explore the in vivo renal clearance, biodistribution, and toxicity responses of the BSA- and GSH-protected gold nanoclusters for 24 hours and 28 days. The BSA-protected gold nanoclusters have low-efficient renal clearance and only 1% of gold can be cleared, but the GSH-protected gold nanoclusters have high-efficient renal clearance and 36 % of gold can be cleared after 24 hours. The biodistribution further reveals that 94% of gold can be metabolized for the GSH-protected nanoclusters, but only less than 5% of gold can be metabolized for the BSA-protected nanoclusters after 28 days. Both of the GSH- and BSA-protected gold nanoclusters cause acute infection, inflammation, and kidney fu...

  7. Highly fluorescent resorcinarene cavitand nanocapsules with efficient renal clearance

    Science.gov (United States)

    Mahadevan, Kalpana; Patthipati, Venkata Suresh; Han, Sangbum; Swanson, R. James; Whelan, Eoin C.; Osgood, Christopher; Balasubramanian, Ramjee

    2016-08-01

    Nanomaterial based imaging approaches hold substantial promise in addressing current diagnostic and therapeutic challenges. One of the key requirements for the successful clinical translation of nanomaterials is their complete clearance from the body within a reasonable time period preferably via the renal filtration route. This article describes the synthesis of highly fluorescent, water soluble, resorcinarene cavitand nanocapsules and demonstrates their effective renal clearance in mice. The synthesis and functionalization of nanocapsules was accomplished in a one-pot operation via thiol-ene reactions without involving self-assembly, sacrificial templates or emulsions. Water soluble resorcinarene cavitand nanocapsules obtained by this approach were covalently functionalized with Alexa Fluor 750. Highly fluorescent nanocapsules with hydrodynamic diameters of 122 nm and 68 nm and extinction coefficients of 1.3 × 109 M‑1 cm‑1 and 1.5 × 108 M‑1 cm‑1 respectively were prepared by varying the reaction conditions. The in vivo biodistribution and clearance of these nanocapsules in mice followed by whole-body fluorescence imaging showed that they were both cleared renally within a few hours. Given the inherent encapsulation capabilities of nanocapsules, the renal clearance demonstrated in this work opens up new opportunities for their theranostic applications especially for targeting and treating the urinary tract.

  8. Influence of clearance model on numerical simulation of centrifugal pump

    Science.gov (United States)

    Wang, Z.; Gao, B.; Yang, L.; Du, W. Q.

    2016-05-01

    Computing models are always simplified to save the computing resources and time. Particularly, the clearance that between impeller and pump casing is always ignored. But the completer model is, the more precise result of numerical simulation is in theory. This paper study the influence of clearance model on numerical simulation of centrifugal pump. We present such influence via comparing performance, flow characteristic and pressure pulsation of two cases that the one of two cases is the model pump with clearance and the other is not. And the results show that the head decreases and power increases so that efficiency decreases after computing with front and back cavities. Then no-leakage model would improve absolute velocity magnitude in order to reach the rated flow rate. Finally, more disturbance induced by front cavity flow and wear-ring flow would change the pressure pulsation of impeller and volute. The performance of clearance flow is important for the whole pump in performance, flow characteristic, pressure pulsation and other respects.

  9. Early clearance of Mycobacterium tuberculosis: a new frontier in prevention

    NARCIS (Netherlands)

    Verrall, A.J.; Netea, M.G.; Alisjahbana, B.; Hill, P.C.; Crevel, R. van

    2014-01-01

    Early clearance (EC) is the successful eradication of inhaled Mycobacterium tuberculosis before an adaptive immune response develops. Evidence for EC comes from case contact studies that consistently show that a proportion of heavily exposed individuals do not develop M. tuberculosis infection. Furt

  10. Comparison of renal clearance of 99mTc-DTPA and inulin 131I-hippurate and PAH as well as creatinine clearance in Wistar-rats

    International Nuclear Information System (INIS)

    Averages and standard deviations of 99mTc-DTPA and 131I-hippurate slope clearance were consecutively determined for 56 male Wistar rats, with a body-weight of 271 ± 69 g in a single investigation. Clearance of 99mTc-DTPA was 17.4 ± 3.4, that of 131I-hippurate was 34.3 ± 7.2 μl · s-1 per 100 g body weight. For 17 rats inulin and PAH clearances were determined after 3 days with the steady-state method with continuous infusion and 3-4 periods of urine collection. During the same periods endogeneous creatinine clearance was determined. 99mTc-DTPA slope clearance correlated well with inulin clearance, also the hippurate with the PAH clearance. The high values of the filtration fraction, calculated from radioisotope and chemical methods, and the low PAH extraction of 42% lead to the conclusion, that PAH and hippurate are incompletely eliminated by the rat kidney from plasma and therefore are inadequate for determining renal blood flow in rats. Creatinine clearance was 4.7 ± 1.38 μl · s-1 per 100 g body weight, much lower than that of inulin and 99mTc-DTPA. Therefore is assumed, that tubular reabsorption of creatinine occurs and creatinine clearance cannot serve for the evaluation of GFR in rats. For this, however, the clearance of 99mTc-DTPA seems well applicable in Wistar rats. (author)

  11. Cell death, clearance and immunity in the skeletal muscle.

    Science.gov (United States)

    Sciorati, C; Rigamonti, E; Manfredi, A A; Rovere-Querini, P

    2016-06-01

    The skeletal muscle is an immunologically unique tissue. Leukocytes, virtually absent in physiological conditions, are quickly recruited into the tissue upon injury and persist during regeneration. Apoptosis, necrosis and autophagy coexist in the injured/regenerating muscles, including those of patients with neuromuscular disorders, such as inflammatory myopathies, dystrophies, metabolic and mitochondrial myopathies and drug-induced myopathies. Macrophages are able to alter their function in response to microenvironment conditions and as a consequence coordinate changes within the tissue from the early injury throughout regeneration and eventual healing, and regulate the activation and the function of stem cells. Early after injury, classically activated macrophages ('M1') dominate the picture. Alternatively activated M2 macrophages predominate during resolution phases and regulate the termination of the inflammatory responses. The dynamic M1/M2 transition is increasingly felt to be the key to the homeostasis of the muscle. Recognition and clearance of debris originating from damaged myofibers and from dying stem/progenitor cells, stromal cells and leukocytes are fundamental actions of macrophages. Clearance of apoptotic cells and M1/M2 transition are causally connected and represent limiting steps for muscle healing. The accumulation of apoptotic cells, which reflects their defective clearance, has been demonstrated in various tissues to prompt autoimmunity against intracellular autoantigens. In the muscle, in the presence of type I interferon, apoptotic myoblasts indeed cause the production of autoantibodies, lymphocyte infiltration and continuous cycles of muscle injury and regeneration, mimicking human inflammatory myopathies. The clearance of apoptotic cells thus modulates the homeostatic response of the skeletal muscle to injury. Conversely, defects in the process may have deleterious local effects, guiding maladaptive tissue remodeling with collagen and fat

  12. Comparison of renal clearance of 99mTc-DTPA and inulin, 131I-hippurate and PAH as well as of the creatinine clearance in Wistar rats

    International Nuclear Information System (INIS)

    Order of magnitude and standard deviation of 99mTc-DTPA and 131I-hippurate slope clearance were analyzed successively in 56 male Wistar rats. The clearance of 99mTc-DTPA was 17.4 ± 3.43 μl · s-1 (100 g b-w)-1, of 131I-hippurate 34.3 ± 7.21 μl · s-1 (100 g b-w)-1. In 17 rats inulin and PAH clearances were analyzed by steady state method with permanent infusion and 3 to 4 urine collection periods 3 days later. The endogeneous creatinine clearance was determined within the same periods. The 99mTc-DTPA slope clearance corresponded to the inulin clearance, as well as the hippurate clearance to the PAH clearance. The high filtration fraction calculated from nuclear medicine and chemical clearance methods and the low PAH extraction (42%) let suggest that PAH and hippurate are eliminated only incompletely from plasma in rat kidney and are unsuitable for determination of renal blood supply in rats. The creatinine clearance with 4.7 ± 1.38 μl · s-1 (100 g b-w)-1 was far beneath the clearance of inulin and 99mTc-DTPA, supposing that creatinine is reabsorbed tubularly in part and the creatinine clearance can not be used for valuation of the GFR in rats. However, for this the 99mTc-DTPA clearance in Wistar rats seems to be well suited. (author)

  13. Mars Rover Local Navigation And Hazard Avoidance

    Science.gov (United States)

    Wilcox, B. H.; Gennery, D. B.; Mishkin, A. H.

    1989-03-01

    A Mars rover sample return mission has been proposed for the late 1990's. Due to the long speed-of-light delays between Earth and Mars, some autonomy on the rover is highly desirable. JPL has been conducting research in two possible modes of rover operation, Computer-Aided Remote Driving and Semiautonomous Navigation. A recently-completed research program used a half-scale testbed vehicle to explore several of the concepts in semiautonomous navigation. A new, full-scale vehicle with all computational and power resources on-board will be used in the coming year to demonstrate relatively fast semiautonomous navigation. The computational and power requirements for Mars rover local navigation and hazard avoidance are discussed.

  14. Analysis of Ares 1 Ascent Navigation Options

    Science.gov (United States)

    Norris, Lee; Tao, Yee-Chee; Hall, Robert; Chuang, Jason; Whorton, Mark

    2008-01-01

    The paper documents a collaborative analysis of ascent Navigation options for the Ares 1 launch vehicle by the NASA Marshall Space Flight Center (MSFC) and the C. S. Draper Laboratory. The objective of the work was the development of a Navigation concept and supporting requirements which meet the Ares 1 accuracy specification in a manner which is straightforward, reliable, and cost effective. Six primary Navigation architectures were considered. In each case analysis was performed to determine under what conditions the required accuracy at second stage cutoff could be achieved. Those architectures which met the accuracy requirements were then assessed in terms of cost, complexity, and reliability to determine a baseline Navigation approach and the primary supporting requirements.

  15. 5th China Satellite Navigation Conference

    CERN Document Server

    Jiao, Wenhai; Wu, Haitao; Lu, Mingquan

    2014-01-01

    China Satellite Navigation Conference (CSNC) 2014 Proceedings presents selected research papers from CSNC2014, held on 21-23 May in Nanjing, China. The theme of CSNC2014 is 'BDS Application: Innovation, Integration and Sharing'. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 9 topics to match the corresponding sessions in CSNC2014, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.  SUN Jiadong is the Chief Designer of the Compass/ BDS, and the Academician of Chinese Academy of Sciences (CAS); JIAO Wenhai is a researcher at China Satellite Navigation Office; WU Haitao is a professor at Navigation Headquarters, CAS; LU Mingquan is a professor at Department of Electronic Engineering of Tsinghua University.

  16. Indoor magnetic navigation for the blind.

    Science.gov (United States)

    Riehle, Timothy H; Anderson, Shane M; Lichter, Patrick A; Giudice, Nicholas A; Sheikh, Suneel I; Knuesel, Robert J; Kollmann, Daniel T; Hedin, Daniel S

    2012-01-01

    Indoor navigation technology is needed to support seamless mobility for the visually impaired. This paper describes the construction of and evaluation of a navigation system that infers the users' location using only magnetic sensing. It is well known that the environments within steel frame structures are subject to significant magnetic distortions. Many of these distortions are persistent and have sufficient strength and spatial characteristics to allow their use as the basis for a location technology. This paper describes the development and evaluation of a prototype magnetic navigation system consisting of a wireless magnetometer placed at the users' hip streaming magnetic readings to a smartphone processing location algorithms. Human trials were conducted to assess the efficacy of the system by studying route-following performance with blind and sighted subjects using the navigation system for real-time guidance. PMID:23366303

  17. Plenoptic Imager for Automated Surface Navigation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Autonomous and semi-autonomous robotic systems require information about their surroundings in order to navigate properly. A video camera machine vision system can...

  18. NOAA Seamless Raster Navigational Charts (RNC)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA Seamless Raster Chart Server provides a seamless collarless mosaic of the NOAA Raster Navigational Charts (RNC). The RNC are a collection of approximately...

  19. Observability analysis of Mars entry integrated navigation

    Science.gov (United States)

    Wang, Liansheng; Xia, Yuanqing

    2015-09-01

    This paper studies three schemes of Mars entry navigation: inertial measurement unit (IMU) based dead reckoning (DR), IMU/orbiter based integrated navigation, and IMU/orbiter/Mars surface beacon (MSB) based integrated navigation. We demonstrate through simulations that first scheme, IMU based DR, produces substantially large state estimation errors. Although these errors are reduced by adding two Mars orbiters, the system is only barely observable. However, by adding two MSBs in above configuration, the position and velocity estimation errors are reduced to the scope of 10 m and 0.5 m/s respectively and the navigation system becomes completely observable. Finally, the estimability of states is investigated; it is observed that velocity variables or velocity variables linear combinations can be estimated better than position variables.

  20. LEO AUTONOMOUS NAVIGATION BASED ON IMAGE MOTION

    Institute of Scientific and Technical Information of China (English)

    DUANFang; LIUJian-ye; YUFeng

    2005-01-01

    A method of LEO autonomous navigation is presented based on the nonlinear satellite velocity relative to the earth. The velocity is detected by a high-speed camera, with the attitude information detected by a star sensor. Compared with traditional autonomous navigation by landmark identification, the satellite velocity relarive to the earth is obtained by correlativity analysis of images. It does not need to recognize ground objects or views. Since it is not necessary to pre-store the database of ground marks, lots of memory space can be saved.The state and observation equations are constructed, and the filtering is processed by the Kalman filter. Simulation results show that the system has high autonomous navigation precision in LEO autonomous navigation.

  1. Navigation with a passive brain based interface

    NARCIS (Netherlands)

    Erp, J.B.F. van; Werkhoven, P.J.; Thurlings, M.E.; Brouwer, A.-M.

    2009-01-01

    In this paper, we describe a Brain Computer Interface (BCI) for navigation. The system is based on detecting brain signals that are elicited by tactile stimulation on the torso indicating the desired direction.

  2. Mars rover local navigation and hazard avoidance

    Science.gov (United States)

    Wilcox, B. H.; Gennery, D. B.; Mishkin, A. H.

    1989-01-01

    A Mars rover sample return mission has been proposed for the late 1990's. Due to the long speed-of-light delays between earth and Mars, some autonomy on the rover is highly desirable. JPL has been conducting research in two possible modes of rover operation, Computer-Aided Remote Driving and Semiautonomous Navigation. A recently-completed research program used a half-scale testbed vehicle to explore several of the concepts in semiautonomous navigation. A new, full-scale vehicle with all computational and power resources on-board will be used in the coming year to demonstrate relatively fast semiautonomous navigation. The computational and power requirements for Mars rover local navigation and hazard avoidance are discussed.

  3. A comparison of analytic procedures for measurement of fractional dextran clearances

    NARCIS (Netherlands)

    Hemmelder, MH; de Jong, PE; de Zeeuw, D

    1998-01-01

    Fractional dextran clearances have been extensively used to study glomerular size selectivity. We report on an analysis of different laboratory procedures involved in measuring fractional dextran clearances. The deproteinization of plasma samples by 20% trichloroacetic acid (TCA) revealed a protein

  4. Indoor Navigation Using an iPhone

    OpenAIRE

    Emilsson, André

    2010-01-01

    Indoor navigation could be used in many applications to enhance performance in its specific area. Anything from serious life critical tasks like aiding firefighters or coordinating military attacks to more simple every day use like finding a desired shop in a large supermarket could be considered. Smartphones of today introduce an interesting platform with capabilities like existing, more clumsy, indoor navigation systems. The iPhone 3GS is a powerful smartphone that lets the programmer use i...

  5. Inertial Navigation and Mapping for Autonomous Vehicles

    OpenAIRE

    Skoglund, Martin

    2014-01-01

    Navigation and mapping in unknown environments is an important building block for increased autonomy of unmanned vehicles, since external positioning systems can be susceptible to interference or simply being inaccessible. Navigation and mapping require signal processing of vehicle sensor data to estimate motion relative to the surrounding environment and to simultaneously estimate various properties of the surrounding environment. Physical models of sensors, vehicle motion and external influ...

  6. Electromagnetic tracking and steering for catheter navigation

    OpenAIRE

    O'Donoghue, Kilian

    2014-01-01

    This thesis explores the use of electromagnetics for both steering and tracking of medical instruments in minimally invasive surgeries. The end application is virtual navigation of the lung for biopsy of early stage cancer nodules. Navigation to the peripheral regions of the lung is difficult due to physical dimensions of the bronchi and current methods have low successes rates for accurate diagnosis. Firstly, the potential use of DC magnetic fields for the actuation of catheter devices with ...

  7. Precise laser gyroscope for autonomous inertial navigation

    International Nuclear Information System (INIS)

    Requirements to gyroscopes of strapdown inertial navigation systems for aircraft application are formulated. The construction of a ring helium – neon laser designed for autonomous navigation is described. The processes that determine the laser service life and the relation between the random error of the angular velocity measurement and the surface relief features of the cavity mirrors are analysed. The results of modelling one of the promising approaches to processing the laser gyroscope signals are presented. (laser gyroscopes)

  8. 19 CFR 4.98 - Navigation fees.

    Science.gov (United States)

    2010-04-01

    ... calculated in accordance with § 24.17(d) Customs Regulations (19 CFR 24.17(d)), and be based upon the amount... 19 Customs Duties 1 2010-04-01 2010-04-01 false Navigation fees. 4.98 Section 4.98 Customs Duties... VESSELS IN FOREIGN AND DOMESTIC TRADES General § 4.98 Navigation fees. (a)(1) The Customs Service...

  9. Applying AHP to Web Navigation Design

    OpenAIRE

    Su-Hua Wang; Che-Hung Lin

    2008-01-01

    Due to increasing popularity of the World Wide Web, web-based systems are widely used. Most corporate web sites try to enhance their usability by providing artistic web presentations. However, the design of web sites is not judged solely on an artistic basis. Two of the most important design criteria for web sites are access to web content and navigation architecture. This research proposes a platform for automatically evaluating the quality of web navigation architecture. Because of the hier...

  10. Sensory mechanisms of animal orientation and navigation

    OpenAIRE

    Muheim, R.; Boström, J.; Åkesson, S.; Liedvogel, M

    2014-01-01

    Although questions such as 'How do animals find their way, and how do they sense and process this information in the brain?' have been asked for centuries , the field of animal orientation and navigation has seen an immense leap forward in the past few decades. Moreover, our understanding has also expanded considerably regarding the molecular and physiological mechanisms of the different compasses and cues used by animals for orientation and navigation (Åkesson et al., Chapter 9, and Svensson...

  11. An integrated platform for inertial navigation systems

    Science.gov (United States)

    Dumitrascu, Ana; Tamas, Razvan D.; Caruntu, George; Bobirca, Daniel

    2015-02-01

    In this paper we propose a new configuration for an inertial navigation system (INS), type strap down, designed to be used onboard a ship. The system consists of an inertial navigation unit (IMU), using a 9-axis inertial sensor and pressure and temperature sensors, a GPS module, various interfaces for optimal communication and command, a microcontroller for data processing and computing and a power supply.

  12. VOR area navigation - Techniques and results

    Science.gov (United States)

    Ragsdale, W. A.

    1982-01-01

    Several methods for deriving position from VOR (without DME) have been developed and evaluated in this study. These methods permit navigation to arbitrary waypoints using either two VOR's or one VOR and a clock. These algorithms have been tested in computer simulations and in flight tests. The single VOR method appears to be the most practical and is a candidate for an automated light plane area navigation system, called VORNAV.

  13. Neurobiologically inspired mobile robot navigation and planning

    OpenAIRE

    Mathias Quoy

    2007-01-01

    After a short review of biologically inspired navigation architectures, mainly relying on modeling the hippocampal anatomy, or at least some of its functions, we present a navigation and planning model for mobile robots. This architecture is based on a model of the hippocampal and prefrontal interactions. In particular, the system relies on the definition of a new cell type “transition cells” that encompasses traditional “place cells”.

  14. Neurobiologically Inspired Mobile Robot Navigation and Planning

    OpenAIRE

    Cuperlier, Nicolas; Quoy, Mathias; Gaussier, Philippe

    2007-01-01

    After a short review of biologically inspired navigation architectures, mainly relying on modeling the hippocampal anatomy, or at least some of its functions, we present a navigation and planning model for mobile robots. This architecture is based on a model of the hippocampal and prefrontal interactions. In particular, the system relies on the definition of a new cell type “transition cells” that encompasses traditional “place cells”.

  15. Neurobiologically inspired mobile robot navigation and planning

    Directory of Open Access Journals (Sweden)

    Mathias Quoy

    2007-11-01

    Full Text Available After a short review of biologically inspired navigation architectures, mainly relying on modeling the hippocampal anatomy, or at least some of its functions, we present a navigation and planning model for mobile robots. This architecture is based on a model of the hippocampal and prefrontal interactions. In particular, the system relies on the definition of a new cell type “transition cells” that encompasses traditional “place cells”.

  16. A Real-Time Autonomous Navigation Architecture

    OpenAIRE

    Chen, Gang; Fraichard, Thierry; Martinez-Gomez, Luis

    2007-01-01

    This paper presents a novel navigation architecture for automated car-like vehicles in urban environments. Motion safety is a critical issue in such environments given that they are partially known and highly dynamic with moving objects (other vehicles, pedestrians...). The main feature of the navigation architecture proposed is its ability to make safe motion decisions in real-time, thus taking into account the harsh constraints imposed by the type of environments considered. The architectur...

  17. Autonomous navigation and sign detector learning

    OpenAIRE

    Ellis, Liam; Pugeault, Nicolas; Öfjäll, Kristoffer; Hedborg, Johan; Bowden, Richard; Felsberg, Michael

    2013-01-01

    This paper presents an autonomous robotic system that incorporates novel Computer Vision, Machine Learning and Data Mining algorithms in order to learn to navigate and discover important visual entities. This is achieved within a Learning from Demonstration (LfD) framework, where policies are derived from example state-to-action mappings. For autonomous navigation, a mapping is learnt from holistic image features (GIST) onto control parameters using Random Forest regression. Additionally, vis...

  18. Precise laser gyroscope for autonomous inertial navigation

    Energy Technology Data Exchange (ETDEWEB)

    Kuznetsov, A G; Molchanov, A V; Izmailov, E A [Joint Stock Company ' Moscow Institute of Electromechanics and Automatics' , Moscow (Russian Federation); Chirkin, M V [Ryazan State Radio Engineering University (Russian Federation)

    2015-01-31

    Requirements to gyroscopes of strapdown inertial navigation systems for aircraft application are formulated. The construction of a ring helium – neon laser designed for autonomous navigation is described. The processes that determine the laser service life and the relation between the random error of the angular velocity measurement and the surface relief features of the cavity mirrors are analysed. The results of modelling one of the promising approaches to processing the laser gyroscope signals are presented. (laser gyroscopes)

  19. Visual navigation for an autonomous mobile vehicle

    OpenAIRE

    Peterson, Kevin Robert

    1992-01-01

    Approved for public release; distribution is unlimited Image understanding for a mobile robotic vehicle is an important and complex task for ensuring safe navigation and extended autonomous operations. The goal of this work is to implement a working vision-based navigation control mechanism within a known environment onboard the autonomous mobile vehicle Yamabico-II. Although installing a working hardware system was not accomplished, the image processing, model description, pattern match...

  20. Effectiveness and Ergonomics of Integrated Navigation System

    OpenAIRE

    Vidan, Pero; Stanivuk, Tatjana; Bielić, Toni

    2012-01-01

    Ergonomics increases the efficiency of people and device interaction. Nowadays, modern navigation bridges are designed in accordance with the requirements of navigators, designers and shipowners, production costs etc. The bridge design, various layouts, instrument arrangements and their capacities etc. have not been fully regulated by the SOLAS convention. The Convention regulates manufacturers’ requirements which refer to accuracy, device sensitivity etc. However, factors that are important ...

  1. Mobility and Navigation among the Yucatec Maya

    OpenAIRE

    Cashdan, Elizabeth; Kramer, Karen L.; Davis, Helen E.; Padilla, Lace; Greaves, Russell D.

    2015-01-01

    Sex differences in range size and navigation are widely reported, with males traveling farther than females, being less spatially anxious, and in many studies navigating more effectively. One explanation holds that these differences are the result of sexual selection, with larger ranges conferring mating benefits on males, while another explanation focuses on greater parenting costs that large ranges impose on reproductive-aged females. We evaluated these arguments with data from a community ...

  2. Location Assurance and Privacy in GNSS Navigation

    OpenAIRE

    Chen, Xihui; Harpes, Carlo; Lenzini, Gabriele; Mauw, Sjouke; Pang, Jun

    2013-01-01

    The growing popularity of location-based services such as GNSS (Global Navigation Satellite System) navigation requires confidence in the reliability of the calculated locations. The exploration of a user’s location also gives rise to severe privacy concerns. Within an ESA (European Space Agency) funded project, we have developed a service that not only verifies the correctness of users’ locations but also enables users to control the accuracy of their revealed locations.

  3. Interactive learning of visual topological navigation

    OpenAIRE

    Filliat, David

    2008-01-01

    International audience We present a topological navigation system that is able to visually recognize the different rooms of an apartment and guide a robot between them. Specifically tailored for small entertainment robots, the system relies on vision only and learns its navigation capabilities incrementally by interacting with a user. This continuous learning strategy makes the system particularly adaptable to environmental lighting and structure modifications. From the computer vision poi...

  4. Target Relative Navigation Results from Hardware-in-the-Loop Tests Using the SINPLEX Navigation System

    OpenAIRE

    Steffes, Stephen; Dumke, Michael; Heise, David; Sagliano, Marco; Samaan, Malak; Theil, Stephan

    2014-01-01

    The goal of the SINPLEX project is to develop an innovative solution to significantly reduce the mass of the navigation subsystem for exploration missions which include landing and/or rendezvous and capture phases. The system mass is reduced while still maintaining good navigation performance as compared to a conventional modular system. This is done by functionally integrating the navigation sensors, using micro- and nanotechnology to miniaturize electronics and fusing the sen...

  5. Simulation-based validation of navigation filter software for a shallow water AUV navigation system (SANS)

    OpenAIRE

    Steven, Ruediger.

    1996-01-01

    Navigation filter software is currently being developed for an inertial navigation system without rotating gyros. This system shall replace the navigation system that is currently used in the Phoenix Autonomous Underwater Vehicle of the Naval Postgraduate School. The filter combines acceleration sensors, angular rate sensors, a water speed sensor, a magnetic compass and a GPS system. The harmonization of the sensors is performed by gain matrices. The filter code must be tested for correctness...

  6. The Mathematics of Navigating the Solar System

    Science.gov (United States)

    Hintz, Gerald

    2000-01-01

    In navigating spacecraft throughout the solar system, the space navigator relies on three academic disciplines - optimization, estimation, and control - that work on mathematical models of the real world. Thus, the navigator determines the flight path that will consume propellant and other resources in an efficient manner, determines where the craft is and predicts where it will go, and transfers it onto the optimal trajectory that meets operational and mission constraints. Mission requirements, for example, demand that observational measurements be made with sufficient precision that relativity must be modeled in collecting and fitting (the estimation process) the data, and propagating the trajectory. Thousands of parameters are now determined in near real-time to model the gravitational forces acting on a spacecraft in the vicinity of an irregularly shaped body. Completing these tasks requires mathematical models, analyses, and processing techniques. Newton, Gauss, Lambert, Legendre, and others are justly famous for their contributions to the mathematics of these tasks. More recently, graduate students participated in research to update the gravity model of the Saturnian system, including higher order gravity harmonics, tidal effects, and the influence of the rings. This investigation was conducted for the Cassini project to incorporate new trajectory modeling features in the navigation software. The resulting trajectory model will be used in navigating the 4-year tour of the Saturnian satellites. Also, undergraduate students are determining the ephemerides (locations versus time) of asteroids that will be used as reference objects in navigating the New Millennium's Deep Space 1 spacecraft autonomously.

  7. Sensor fusion for improved indoor navigation

    Science.gov (United States)

    Emilsson, Erika; Rydell, Joakim

    2012-09-01

    A reliable indoor positioning system providing high accuracy has the potential to increase the safety of first responders and military personnel significantly. To enable navigation in a broad range of environments and obtain more accurate and robust positioning results, we propose a multi-sensor fusion approach. We describe and evaluate a positioning system, based on sensor fusion between a foot-mounted inertial measurement unit (IMU) and a camera-based system for simultaneous localization and mapping (SLAM). The complete system provides accurate navigation in many relevant environments without depending on preinstalled infrastructure. The camera-based system uses both inertial measurements and visual data, thereby enabling navigation also in environments and scenarios where one of the sensors provides unreliable data during a few seconds. When sufficient light is available, the camera-based system generally provides good performance. The foot-mounted system provides accurate positioning when distinct steps can be detected, e.g., during walking and running, even in dark or smoke-filled environments. By combining the two systems, the integrated positioning system can be expected to enable accurate navigation in almost all kinds of environments and scenarios. In this paper we present results from initial tests, which show that the proposed sensor fusion improves the navigation solution considerably in scenarios where either the foot-mounted or camera-based system is unable to navigate on its own.

  8. NFC internal: an indoor navigation system.

    Science.gov (United States)

    Ozdenizci, Busra; Coskun, Vedat; Ok, Kerem

    2015-01-01

    Indoor navigation systems have recently become a popular research field due to the lack of GPS signals indoors. Several indoors navigation systems have already been proposed in order to eliminate deficiencies; however each of them has several technical and usability limitations. In this study, we propose NFC Internal, a Near Field Communication (NFC)-based indoor navigation system, which enables users to navigate through a building or a complex by enabling a simple location update, simply by touching NFC tags those are spread around and orient users to the destination. In this paper, we initially present the system requirements, give the design details and study the viability of NFC Internal with a prototype application and a case study. Moreover, we evaluate the performance of the system and compare it with existing indoor navigation systems. It is seen that NFC Internal has considerable advantages and significant contributions to existing indoor navigation systems in terms of security and privacy, cost, performance, robustness, complexity, user preference and commercial availability. PMID:25825976

  9. NFC Internal: An Indoor Navigation System

    Directory of Open Access Journals (Sweden)

    Busra Ozdenizci

    2015-03-01

    Full Text Available Indoor navigation systems have recently become a popular research field due to the lack of GPS signals indoors. Several indoors navigation systems have already been proposed in order to eliminate deficiencies; however each of them has several technical and usability limitations. In this study, we propose NFC Internal, a Near Field Communication (NFC-based indoor navigation system, which enables users to navigate through a building or a complex by enabling a simple location update, simply by touching NFC tags those are spread around and orient users to the destination. In this paper, we initially present the system requirements, give the design details and study the viability of NFC Internal with a prototype application and a case study. Moreover, we evaluate the performance of the system and compare it with existing indoor navigation systems. It is seen that NFC Internal has considerable advantages and significant contributions to existing indoor navigation systems in terms of security and privacy, cost, performance, robustness, complexity, user preference and commercial availability.

  10. Consumer Response to Seasonal Clearance Sales: Experimental Analysis of Consumer Personality Traits in Self Service Stores

    OpenAIRE

    Rajagopal, MR

    2006-01-01

    Consumer responses to clearance sales, both in terms of consumer satisfaction with the decision process and in terms of subsequent store choice behavior, are explored in the paper through four controlled experiments conducted involving clearance sales in a consumer choice and decision satisfaction context. The results suggest that consumer response to clearance sales is driven to a large extent by two factors: the effect of a clearance sale on the available options of goods and the degree of ...

  11. 48 CFR 245.7101-4 - DD Form 1640, Request for Plant Clearance.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 1640, Request for Plant Clearance. 245.7101-4 Section 245.7101-4 Federal Acquisition Regulations System DEFENSE... Forms 245.7101-4 DD Form 1640, Request for Plant Clearance. Use to request plant clearance assistance...

  12. The relationship between the renal clearance of creatinine and the apparent renal clearance of beta-2-microglobulin in patients with normal and impaired kidney function.

    Science.gov (United States)

    Vree, T B; Guelen, P J; Jongman-Nix, B; Walenkamp, G H

    1981-07-18

    The renal clearances of creatinine and beta 2-microglobulin of patients with either normal or impaired kidney function were measured. The renal clearance of beta 2-microglobulin depends on the urinary pH and must be considered as an apparent renal clearance because after tubular reabsorption the compound is metabolized in the kidney. Impaired kidney function reduces the percentage of tubular reabsorption of beta 2-microglobulin. PMID:6166414

  13. Nanoparticle clearance from the airways : development and testing of a new in vitro model to investigate mucociliary clearance of aerosol particles

    OpenAIRE

    Henning, Andreas Michael

    2008-01-01

    The current challenge in pulmonary drug delivery is to overcome and to control drug clearance from the lung. Here, the interaction with the mucociliary lung clearance plays a key role for any drug formulation technology. By today many open questions on mucociliary clearance (MC) have to be answered but suffer from limited experimental options. Considering these facts, the central part of this work was to develop a new in vitro test model to investigate the complex mechanism of MC more detaile...

  14. A stochastic analysis of terrain evaluation variables for path selection. [roving vehicle navigation

    Science.gov (United States)

    Donohue, J. G.; Shen, C. N.

    1978-01-01

    A stochastic analysis was performed on the variables associated with the characteristics of the terrain encountered by a roving system with an autonomous navigation system. A laser rangefinder is employed to detect terrain features at ranges up to 75 m. Analytic expressions and a numerical scheme were developed to calculate the variance of data on these four variables: (1) body clearance, (2) in-path slope, (3) tilt slope, and (4) wheel deviation. The variance is due to noise in the range data. It was found that the standard deviation of these terrain variables is large enough to warrant the use of a safety margin to aid the roving vehicle in avoiding high risk areas.

  15. 33 CFR 245.20 - Determination of hazard to navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Determination of hazard to..., DEPARTMENT OF DEFENSE REMOVAL OF WRECKS AND OTHER OBSTRUCTIONS § 245.20 Determination of hazard to navigation... Coast Guard district to jointly determine whether the obstruction poses a hazard to navigation....

  16. Cognitive Costs of Navigation Aids in Hypermedia Learning

    Science.gov (United States)

    Waniek, Jacqueline; Ewald, Karolin

    2008-01-01

    This study examines the cognitive costs of navigation aids in a hypermedia learning task. In a 2(navigable vs. non-navigable) x 2(map vs. content list) experimental design cognitive requirements were measured by users' eye movement data. Additionally, data from users' navigation operations, knowledge acquisition, and subjective evaluation of the…

  17. 33 CFR 66.01-50 - Protection of private aids to navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Protection of private aids to navigation. 66.01-50 Section 66.01-50 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION PRIVATE AIDS TO NAVIGATION Aids to Navigation Other Than Federal or State §...

  18. Preparation of iodine-125-labeled iothalamate for renal clearance measurements

    International Nuclear Information System (INIS)

    Iothalamate, a derivative of benzoic acid, is used as a contrast medium for renal function studies, particularly for measurement of glomerular filtration rate. Its chemical composition and clearance properties are similar to those of diatrizoate. The structural differences between these groups of iodinated benzoic acid derivatives are dependent on the groups attached at the 3- and 5-positions of 2,4,6-tri-iodobenzoic acid. The renal clearance of sodium iothalamate in humans closely approximates that of inulin, and it is used as a replacement for inulin in determining glomerular filtration rate. /sup 125/I-labeled iothalamate sodium can be prepared by the exchange-labeling method at pH 4.0. Iothalamate must first be isolated from the contrast medium preparation and purified before radioiodination. After radioiodination, the product is purified by means of precipitation and is then converted to the sodium salt

  19. Clearance of nuclear waste and decommissioned nuclear facilities

    Energy Technology Data Exchange (ETDEWEB)

    2008-07-01

    The guide is applied to waste, including recyclable materials, arising from the operation and decommissioning of a nuclear facility, as well as to non-dismantled buildings and surrounding sites being subject to regulatory control. The guide gives the radiation protection principles to be followed in the planning and implementation of clearances. The guide also covers the clearance procedures and the activity monitoring and record-keeping of materials to be cleared. The guide does not address radioactive waste or contaminated sites arising as a consequence of the utilization of natural resources. The guidance for such activities is given in Section 13 of the Finnish Radiation Act, Section 6 of the Radiation Decree and in STUK's (Finnish Radiation and Nuclear Safety Authority) guides ST 6.2, ST 12.1 and ST 12.2

  20. Numerical analysis of bump foil bearings without nominal radial clearance

    Institute of Scientific and Technical Information of China (English)

    LIU Zhan-sheng; XU Huai-jin; ZHANG Guang-hui

    2008-01-01

    Bump foil bearings without nominal radial clearance were analyzed. An air film thickness model and a bearing theoretical analytical model were developed accounting for air compressibility and foil deformation. To analyze hydrodynamic characteristics of bump foil beatings with different operating eccentricities, the air film thickness equation and Reynolds equation were coupled through pressure and solved by Newton-Raphson Method(NRM) and Finite Difference Method (FDM). The characteristics of an bump foil bearing model were dis-cussed including load carrying capacity, film thickness and pressure distributions. The results of simulation show that bump foil beating without nominal radial clearance can provide better stability and greater load capaci-ty. This numerical analytical method also reveals a good convergence in numerical calculation.

  1. Effect of surface-active substance on nasal mucociliary clearance time

    DEFF Research Database (Denmark)

    Outzen, K E; Svane-Knudsen, V

    1993-01-01

    Mucociliary clearance measured by saccharin clearance time is depending on ciliary function and on the physiological characteristics of mucus. The aim of this study was to determine whether the application of surface-active substances changed the mucociliary transport time. Twenty healthy persons...... were manually sprayed with surface-active substance in one of their nose cavities. The saccharin clearance time was measured before spraying and statistically compared with saccharin clearance time after spraying. Saccharin clearance time was significantly shortened immediately after spraying with...

  2. Speech Recognition Technology Applied to Intelligent Mobile Navigation System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The capability of human-computer interaction reflects the intelligent degree of mobile navigation system.The navigation data and functions of mobile navigation system are divided into system commands and non-system commands in this paper.And then a group of speech commands are Abstracted.This paper applies speech recognition technology to intelligent mobile navigation system to process speech commands and does some deep research on the integration of speech recognition technology with mobile navigation system.The navigation operation can be performed by speech commands,which makes human-computer interaction easy during navigation.Speech command interface of navigation system is implemented by Dutty ++ Software,which is based on speech recognition system -Via Voice of IBM.Through navigation experiments,navigation can be done almost without keyboard,which proved that human-computer interaction is very convenient by speech commands and the reliability is also higher.

  3. Intelligent navigation to improve obstetrical sonography.

    Science.gov (United States)

    Yeo, Lami; Romero, Roberto

    2016-04-01

    'Manual navigation' by the operator is the standard method used to obtain information from two-dimensional and volumetric sonography. Two-dimensional sonography is highly operator dependent and requires extensive training and expertise to assess fetal anatomy properly. Most of the sonographic examination time is devoted to acquisition of images, while 'retrieval' and display of diagnostic planes occurs rapidly (essentially instantaneously). In contrast, volumetric sonography has a rapid acquisition phase, but the retrieval and display of relevant diagnostic planes is often time-consuming, tedious and challenging. We propose the term 'intelligent navigation' to refer to a new method of interrogation of a volume dataset whereby identification and selection of key anatomical landmarks allow the system to: 1) generate a geometrical reconstruction of the organ of interest; and 2) automatically navigate, find, extract and display specific diagnostic planes. This is accomplished using operator-independent algorithms that are both predictable and adaptive. Virtual Intelligent Sonographer Assistance (VIS-Assistance®) is a tool that allows operator-independent sonographic navigation and exploration of the surrounding structures in previously identified diagnostic planes. The advantage of intelligent (over manual) navigation in volumetric sonography is the short time required for both acquisition and retrieval and display of diagnostic planes. Intelligent navigation technology automatically realigns the volume, and reorients and standardizes the anatomical position, so that the fetus and the diagnostic planes are consistently displayed in the same manner each time, regardless of the fetal position or the initial orientation. Automatic labeling of anatomical structures, subject orientation and each of the diagnostic planes is also possible. Intelligent navigation technology can operate on conventional computers, and is not dependent on specific ultrasound platforms or on the

  4. Integrated navigation method of a marine strapdown inertial navigation system using a star sensor

    International Nuclear Information System (INIS)

    This paper presents an integrated navigation method of the strapdown inertial navigation system (SINS) using a star sensor. According to the principle of SINS, its own navigation information contains an error that increases with time. Hence, the inertial attitude matrix from the star sensor is introduced as the reference information to correct the SINS increases error. For the integrated navigation method, the vehicle’s attitude can be obtained in two ways: one is calculated from SINS; the other, which we have called star sensor attitude, is obtained as the product between the SINS position and the inertial attitude matrix from the star sensor. Therefore, the SINS position error is introduced in the star sensor attitude error. Based on the characteristics of star sensor attitude error and the mathematical derivation, the SINS navigation errors can be obtained by the coupling calculation between the SINS attitude and the star sensor attitude. Unlike several current techniques, the navigation process of this method is non-radiating and invulnerable to jamming. The effectiveness of this approach was demonstrated by simulation and experimental study. The results show that this integrated navigation method can estimate the attitude error and the position error of SINS. Therefore, the SINS navigation accuracy is improved. (paper)

  5. Peculiarities of future air navigation system based on inertial navigation systems/global positioning system

    OpenAIRE

    Sineglazov, V. M.; National Aviation University,; Zakharin, F. M.; National Aviation University

    2014-01-01

    Using an inertial navigation system and Global Positioning System together is preferable to using any of them separately. Derived benefits depend on the level of combining information. Inertial navigation systems/Global Positioning System integration architectures are defined as separate, loosely and tightly coupled, deeply integrated configurations.

  6. Does Navigation Always Predict Performance? Effects of Navigation on Digital Reading Are Moderated by Comprehension Skills

    Science.gov (United States)

    Naumann, Johannes; Salmerón, Ladislao

    2016-01-01

    This study investigated interactive effects of navigation and offline comprehension skill on digital reading performance. As indicators of navigation, relevant page selection and irrelevant page selection were considered. In 533 Spanish high school students aged 11-17 positive effects of offline comprehension skill and relevant page selection on…

  7. Target relative navigation results from hardware-in-the-loop tests using the sinplex navigation system

    NARCIS (Netherlands)

    Steffes, S.; Dumke, M.; Heise, D.; Sagliano, M.; Samaan, M.; Theil, S.; Boslooper, E.C.; Oosterling, J.A.J.; Schulte, J.; Skaborn, D.; Söderholm, S.; Conticello, S.; Esposito, M.; Yanson, Y.; Monna, B.; Stelwagen, F.; Visee, R.

    2014-01-01

    The goal of the SINPLEX project is to develop an innovative solution to significantly reduce the mass of the navigation subsystem for exploration missions which include landing and/or rendezvous and capture phases. The system mass is reduced while still maintaining good navigation performance as com

  8. Integrated navigation method of a marine strapdown inertial navigation system using a star sensor

    Science.gov (United States)

    Wang, Qiuying; Diao, Ming; Gao, Wei; Zhu, Minghong; Xiao, Shu

    2015-11-01

    This paper presents an integrated navigation method of the strapdown inertial navigation system (SINS) using a star sensor. According to the principle of SINS, its own navigation information contains an error that increases with time. Hence, the inertial attitude matrix from the star sensor is introduced as the reference information to correct the SINS increases error. For the integrated navigation method, the vehicle’s attitude can be obtained in two ways: one is calculated from SINS; the other, which we have called star sensor attitude, is obtained as the product between the SINS position and the inertial attitude matrix from the star sensor. Therefore, the SINS position error is introduced in the star sensor attitude error. Based on the characteristics of star sensor attitude error and the mathematical derivation, the SINS navigation errors can be obtained by the coupling calculation between the SINS attitude and the star sensor attitude. Unlike several current techniques, the navigation process of this method is non-radiating and invulnerable to jamming. The effectiveness of this approach was demonstrated by simulation and experimental study. The results show that this integrated navigation method can estimate the attitude error and the position error of SINS. Therefore, the SINS navigation accuracy is improved.

  9. RENAL CLEARANCE AND URINARY EXCRETION OF CIPROFLOXACIN IN GOATS

    OpenAIRE

    Z. IQBAL, I. JAVED, B. ASLAM, F. MUHAMMAD AND I. U. JAN

    2007-01-01

    The renal clearance and urinary excretion of ciprofloxacin were investigated in eight healthy female goats. In each animal, ciprofloxacin was administered intramuscularly at the rate of 5 mg/kg body weight. Following drug administration, blood and urine samples were collected at different time intervals and analyzed for ciprofloxacin and creatinine. High performance liquid chromatography (HPLC) was used to determine the drug concentration in the plasma and urine. The value of diuresis after s...

  10. DOES BODY MASS INDEX INFLUENCE NASAL MUCOCILIARY CLEARANCE?

    Directory of Open Access Journals (Sweden)

    Tamilselvan K, Latha R, Nirmala N, Susiganeshkumar E, Thananjayam A

    2015-01-01

    Full Text Available Background: The respiratory system is constantly exposed to particulate matter suspended in the inhaled air and one among the efficient mechanisms to trap and expel the particulate substances is the nasal and bronchial mucociliary clearance mechanism. This mucociliary clearance mechanism is influenced by both physiological and pathological factors that alter the functioning of the respiratory cilia and the overlying mucosal layer that traps the particulate agents. As Body mass index (BMI determines the health of a person by influencing various physiological parameters, this study has been planned to study the effect of normal and abnormal BMI (overweight and obese range on the nasal mucociliary clearance (NMC. Aim: To evaluate the effect of BMI on nasal mucociliary clearance (NMC. Materials & Methods: NMC was measured in 20 volunteers with normal BMI (18.5-22.9 Kg/m2 and 20 volunteers with BMI in overweight and obese range (23 Kg/m2 and above. The NMC time was recorded by the time the volunteers appreciated the sweet taste following the placement of ¼ of saccharin tablet (1mm x 1mm in the nostril referred as saccharin transit time (STT.Results: NMC was found to be prolonged in overweight and obese population and BMI has positive correlation with NMC as calculated by Pearson correlation with r value of 0.591 and p value 0.001 which is statistically significant. Conclusion: NMC time is prolonged in abnormal BMI referring to the impairment in the mucociliary escalator mechanism thus predisposing to disease states.

  11. Surface code—biophysical signals for apoptotic cell clearance

    International Nuclear Information System (INIS)

    Apoptotic cell death and the clearance of dying cells play an important and physiological role in embryonic development and normal tissue turnover. In contrast to necrosis, apoptosis proceeds in an anti-inflammatory manner. It is orchestrated by the timed release and/or exposure of so-called ‘find-me’, ‘eat me’ and ‘tolerate me’ signals. Mononuclear phagocytes are attracted by various ‘find-me’ signals, including proteins, nucleotides, and phospholipids released by the dying cell, whereas the involvement of granulocytes is prevented via ‘stay away’ signals. The exposure of anionic phospholipids like phosphatidylserine (PS) by apoptotic cells on the outer leaflet of the plasma membrane is one of the main ‘eat me’ signals. PS is recognized by a number of innate receptors as well as by soluble bridging molecules on the surface of phagocytes. Importantly, phagocytes are able to discriminate between viable and apoptotic cells both exposing PS. Due to cytoskeleton remodeling PS has a higher lateral mobility on the surfaces of apoptotic cells thereby promoting receptor clustering on the phagocyte. PS not only plays an important role in the engulfment process, but also acts as ‘tolerate me’ signal inducing the release of anti-inflammatory cytokines by phagocytes. An efficient and fast clearance of apoptotic cells is required to prevent secondary necrosis and leakage of intracellular danger signals into the surrounding tissue. Failure or prolongation of the clearance process leads to the release of intracellular antigens into the periphery provoking inflammation and development of systemic inflammatory autoimmune disease like systemic lupus erythematosus. Here we review the current findings concerning apoptosis-inducing pathways, important players of apoptotic cell recognition and clearance as well as the role of membrane remodeling in the engulfment of apoptotic cells by phagocytes. (paper)

  12. Mathematical modeling and analysis of insulin clearance in vivo

    OpenAIRE

    Koschorreck, Markus; Gilles, Ernst Dieter

    2008-01-01

    Background Analyzing the dynamics of insulin concentration in the blood is necessary for a comprehensive understanding of the effects of insulin in vivo. Insulin removal from the blood has been addressed in many studies. The results are highly variable with respect to insulin clearance and the relative contributions of hepatic and renal insulin degradation. Results We present a dynamic mathematical model of insulin concentration in the blood and of insulin receptor activation in hepatocytes. ...

  13. Mathematical modeling and analysis of insulin clearance in vivo

    OpenAIRE

    Koschorreck, M.; Gilles, E. D.

    2008-01-01

    Background: Analyzing the dynamics of insulin concentration in the blood is necessary for a comprehensive understanding of the effects of insulin in vivo. Insulin removal from the blood has been addressed in many studies. The results are highly variable with respect to insulin clearance and the relative contributions of hepatic and renal insulin degradation. Results: We present a dynamic mathematical model of insulin concentration in the blood and of insulin receptor acti...

  14. Mathematical modeling and analysis of insulin clearance in vivo

    OpenAIRE

    Koschorreck, M.; Gilles, E.

    2008-01-01

    Background: Analyzing the dynamics of insulin concentration in the blood is necessary for a comprehensive understanding of the effects of insulin in vivo. Insulin removal from the blood has been addressed in many studies. The results are highly variable with respect to insulin clearance and the relative contributions of hepatic and renal insulin degradation. Results: We present a dynamic mathematical model of insulin concentration in the blood and of insulin receptor activation in hepatocytes...

  15. Mucociliary clearance, airway inflammation and nasal symptoms in urban motorcyclists

    OpenAIRE

    Brant, Tereza C S; Yoshida, Carolina T; de S. Carvalho, Tomas; Marina L. Nicola; Jocimar A. Martins; Lays M. Braga; de Oliveira, Regiani C; Leyton, Vilma; Carmen S. de André; Saldiva, Paulo H N; Rubin, Bruce K; Naomi K. Nakagawa

    2014-01-01

    OBJECTIVES: There is evidence that outdoor workers exposed to high levels of air pollution exhibit airway inflammation and increased airway symptoms. We hypothesized that these workers would experience increased airway symptoms and decreased nasal mucociliary clearance associated with their exposure to air pollution. METHODS: In total, 25 non-smoking commercial motorcyclists, aged 18-44 years, were included in this study. These drivers work 8-12 hours per day, 5 days per week, driving on urba...

  16. Respiratory Protection Program medical clearance for respirator use

    Science.gov (United States)

    1993-01-01

    Background on occupational exposure to various inhalents is discussed including on-site hazard control measures, procedures, physiological effects, and interpretation of results for the medical clearance of employee for use of personal respiratory protection devices. The purpose of the Respiratory Protection Program at LeRC is outlined, and the specifics of the Medical Surveillance Program for Respiratory Protection at LeRC are discussed.

  17. Lactadherin and clearance of platelet-derived microvesicles

    OpenAIRE

    Dasgupta, Swapan K.; Abdel-Monem, Hanan; Niravath, Polly; Le, Anhquyen; Bellera, Ricardo V.; Langlois, Kimberly; Nagata, Shigekazu; Rumbaut, Rolando E.; Thiagarajan, Perumal

    2009-01-01

    The transbilayer movement of phosphatidylserine from the inner to the outer leaflet of the membrane bilayer during platelet activation is associated with the release of procoagulant phosphatidylserine-rich small membrane vesicles called platelet-derived microvesicles. We tested the effect of lactadherin, which promotes the phagocytosis of phosphatidylserine-expressing lymphocytes and red blood cells, in the clearance of platelet microvesicles. Platelet-derived microvesicles were labeled with ...

  18. Apoptotic clearance in rabbits with experimental pulmonary emphysema

    OpenAIRE

    Žunić-Božinovski Snežana; Žunić Svetlana; Mladenović-Đorđević Aleksandra; Ruždijić Sabera; Kanazir Selma

    2011-01-01

    In order to better understand pathogenesis of pulmonary emphysema, the model of experimentally induced pulmonary emphysema in Chinchilla rabbits was used for the estimation of apoptotic clearance of pulmonary tissue. Bronchoalveolar lavage was performed in three groups of animals: experimental group-E on hypercholesterolemic diet (4% edible oil solution of crystalline cholesterol), control group-C1 on standard diet for that animal species and animals on oil...

  19. Early clearance of pneumococci from the lungs of decomplemented rats.

    OpenAIRE

    Rehm, S R; Coonrod, J D

    1982-01-01

    Pneumococcal types which exhibited varying degrees of interaction with the complement system in vitro wee aerosolized into normal and decomplemented rats, and the rate of killing of pneumococci was monitored by serial cultures of whole lung homogenates. The clearance of pneumococci from the alveoli did not correlate with the ability of the pneumococci to be opsonized by complement in vitro. Similarly, rats depleted of complement in the serum and the bronchoalveolar lavage fluid maintained the...

  20. Mine clearance industry: background, geography, funding, analysis and future projections

    OpenAIRE

    Donmez, Erkan

    2007-01-01

    MBA Professional Report Approved for public release; distribution is unlimited Contrary to common belief, the problems caused by landmines or other counter mobility devices have been threatening the lives of human beings for thousands of years. However, the actual efforts to remove the buried mines are a comparatively new issue. The mine clearance industry has been growing steadily, mostly because of increasing demand from the mine-afflicted countries, NGOs, international organizati...

  1. Highly Catalytic Nanodots with Renal Clearance for Radiation Protection

    OpenAIRE

    Zhang, Xiao-Dong; Zhang, Jinxuan; Wang, Junying; Yang, Jiang; Chen, Jie; Shen, Xiu; Deng, Jiao; Deng, Dehui; Long, Wei; Sun, Yuan-Ming; Liu, Changlong; Li, Meixian

    2016-01-01

    Ionizing radiation (gamma and x-ray) is widely used in industry and medicine, but it can also pose a significant hazardous effect on health and induce cancer, physical deformity and even death, due to DNA damages and invasion of free radicals. There is therefore an urgent unmet demand in designing highly efficient radioprotectants with synergetic integration of effective renal clearance and low toxicity. In this study, we designed ultrasmall (sub-5 nm) highly catalytically active and cysteine...

  2. Lung Clearance Index bei erwachsenen Patienten mit Mukoviszidose

    OpenAIRE

    Rückel, Helena Sophie

    2011-01-01

    Die Spirometrie mit Bestimmung des forcierten exspiratorischen Volumens in einer Sekunde gilt derzeit als Gold-Standard bei der Beurteilung der Lungenfunktion von Patienten mit Cystischer Fibrose. Da die spirometrische Untersuchung eine aktive Mitarbeit des Patienten erfordert, kann sie jedoch erst etwa ab dem fünften Lebensjahr durchgeführt werden. Im Gegensatz dazu kann der Lung Clearance Index (LCI), der aus Gasdilutionsuntersuchungen abgeleitet wird, in jedem Alter, d.h. auch im Säugl...

  3. Guangzhou Customs Guide to "Local Declaration & Port Clearance"

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Ⅰ.Characteristic of the supervision mode of "Local Declaration & Port Clearance" This new mode means that the consignor,consignee or agent (hereafter referred to as "declarant") could choose any competent customs under the jurisdiction of Guangzhou Customs to make declaration and go through the formalities of document-checking and duty-paying,and then finish the cargo-examination and cargo-release at the customs office of entry or exit.

  4. Navigation Architecture for a Space Mobile Network

    Science.gov (United States)

    Valdez, Jennifer E.; Ashman, Benjamin; Gramling, Cheryl; Heckler, Gregory W.; Carpenter, Russell

    2016-01-01

    The Tracking and Data Relay Satellite System (TDRSS) Augmentation Service for Satellites (TASS) is a proposed beacon service to provide a global, space based GPS augmentation service based on the NASA Global Differential GPS (GDGPS) System. The TASS signal will be tied to the GPS time system and usable as an additional ranging and Doppler radiometric source. Additionally, it will provide data vital to autonomous navigation in the near Earth regime, including space weather information, TDRS ephemerides, Earth Orientation Parameters (EOP), and forward commanding capability. TASS benefits include enhancing situational awareness, enabling increased autonomy, and providing near real-time command access for user platforms. As NASA Headquarters' Space Communication and Navigation Office (SCaN) begins to move away from a centralized network architecture and towards a Space Mobile Network (SMN) that allows for user initiated services, autonomous navigation will be a key part of such a system. This paper explores how a TASS beacon service enables the Space Mobile Networking paradigm, what a typical user platform would require, and provides an in-depth analysis of several navigation scenarios and operations concepts. This paper provides an overview of the TASS beacon and its role within the SMN and user community. Supporting navigation analysis is presented for two user mission scenarios: an Earth observing spacecraft in low earth orbit (LEO), and a highly elliptical spacecraft in a lunar resonance orbit. These diverse flight scenarios indicate the breadth of applicability of the TASS beacon for upcoming users within the current network architecture and in the SMN.

  5. Relationship Between Tongue Base Region Pressures and Vallecular Clearance.

    Science.gov (United States)

    Knigge, Molly A; Thibeault, Susan

    2016-06-01

    Tongue base pressures have been thought to provide primary bolus clearance through the pharynx during swallowing. The relationship between bolus driving pressures and residue remaining in the valleculae after the swallow has not been defined. Thirty-seven dysphagic patients who were evaluated with both videofluoroscopy (VFSS) and high-resolution manometry (HRM) were identified within the University of Wisconsin Voice and Swallowing Outcomes database. Patients were categorized according to binary ratings of presence or absence of vallecular stasis as well as incomplete or complete tongue retraction on VFSS. Tongue base region pressures measured with HRM during saline swallows of 1 and 10 ml volumes were compared to ratings of vallecular stasis or tongue base retraction. No significant difference could be identified among mean peak HRM pressures when compared to presence or absence of vallecular stasis (1 ml saline: p = .1886; 10 ml saline: p = .7354). When categorized according to complete or incomplete tongue retraction, mean peak HRM pressures were significantly greater in the complete tongue retraction group as compared to incomplete tongue retraction (1 ml saline: p = .0223; 10 ml saline: p = .0100). Findings suggest there are multiple factors that lead to reduced vallecular clearance. In the absence of HRM measures, judging complete or incomplete tongue retraction on VFSS may be a more valid gauge of tongue base region pressures than vallecular clearance when planning dysphagia treatment. PMID:26796743

  6. Smoking produced mucus and clearance of particulates in the lung

    International Nuclear Information System (INIS)

    Some studies of miners have shown a lesser relative lung-cancer risk for smokers than for nonsmokers. For example, experiments by Cross and associates with dogs have shown an apparent protective effect of cigarette smoke against radon-daughter and dust exposure. One reason for these changes may be the thickened mucus layer in the tracheobronchial region of smokers. Physiological changes in the lung due to smoking may decrease the effects of radioactive particles in cancers in the bronchial region by apparently promoting faster clearance, in that region, of radioactive particles and by decreasing the radiation dose through reduced penetration to the sensitive basal epithelial cells. Because of the short half-life of radon daughters, even if there is possible tobacco-related delay of particle clearance from the alveolar region it cannot affect radon clearance. Therefore, the possible mitigating effect of tobacco on radon-produced cancer appears to be limited to the tracheobronchial region. It would be of value to a number of occupations if the same changes in the lungs due to smoking could be produced in exposed workers in the absence of cigarette-smoking. Beta-carotene and vitamin A, which affect maintenance and secretion of the mucosal lining, appear to thicken mucus, thereby providing protection against radon-induced lung cancers that is similar to smoking-related changes in the lung

  7. Respirable industrial fibres: deposition, clearance and dissolution in animal models.

    Science.gov (United States)

    Jones, A D

    1993-04-01

    This paper examines the available experimental and theoretical results describing deposition and clearance of mineral fibres inhaled by animals and humans in order to define the limits which these mechanisms impose on the relevance of animal experiments in the assessment of potential human health risks. Direct experimental data for deposition of spherical particles are extended by examination of the physical processes and by some limited experimental data for fibres. This shows that alveolar deposition efficiency (in rat and in man) is sufficiently similar for particles and fibres with aerodynamic diameters less that 5 microns for rats to be a relevant model for airborne dusts in this size range. Inter-species differences in mechanical clearance are substantial, with clearance being faster in the rat than in man, and this is a factor which should be considered in interpreting animal toxicity studies. The durability of fibres in the biochemical conditions of the lung may be more important over the longer lifespan of humans. PMID:8317856

  8. Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency

    Directory of Open Access Journals (Sweden)

    Kavya Reddy

    2016-03-01

    Full Text Available Attenuated auto-lysosomal system has been associated with Alzheimer disease (AD, yet all underlying molecular mechanisms leading to this impairment are unknown. We show that the amino acid sensing of mechanistic target of rapamycin complex 1 (mTORC1 is dysregulated in cells deficient in presenilin, a protein associated with AD. In these cells, mTORC1 is constitutively tethered to lysosomal membranes, unresponsive to starvation, and inhibitory to TFEB-mediated clearance due to a reduction in Sestrin2 expression. Normalization of Sestrin2 levels through overexpression or elevation of nuclear calcium rescued mTORC1 tethering and initiated clearance. While CLEAR network attenuation in vivo results in buildup of amyloid, phospho-Tau, and neurodegeneration, presenilin-knockout fibroblasts and iPSC-derived AD human neurons fail to effectively initiate autophagy. These results propose an altered mechanism for nutrient sensing in presenilin deficiency and underline an importance of clearance pathways in the onset of AD.

  9. Characterization and Clearance of m/s Sigyn

    International Nuclear Information System (INIS)

    M/s Sigyn was a 2044 ton ship that transported contaminated material between 1982 and 2013. Most of the transports were with spent nuclear fuel between Swedish nuclear power plants and the Swedish fuel repository, Clab. In addition to spent fuel, m/s Sigyn also transported big contaminated components, from nuclear power plants in Europe, to Studsvik for analysis or decontamination and melting. She also transported components from Swedish nuclear power plants to final disposal of short lived waste, SFR. Even though all transported items have been cleaned, checked and wrapped with plastics, some activity ended up as contamination onboard. In December 2013 it was decided that m/s Sigyn was subject for decommissioning due to her age. This Paper describes the method in which the activity onboard m/s Sigyn was characterized and clearance levels were calculated. This method for radiological characterization and clearance has recently been developed in Sweden, the method is efficient in that it does not need a big pre characterization survey. Only the nuclide distribution and history of the object, is needed to start the final survey. In the future there will be further development of the method, making it possible to reduce the number of measurements even more. This will further optimize the method and reduce the cost for final surveys and clearance. (authors)

  10. RENAL CLEARANCE AND URINARY EXCRETION OF CIPROFLOXACIN IN GOATS

    Directory of Open Access Journals (Sweden)

    Z. IQBAL, I. JAVED, B. ASLAM, F. MUHAMMAD AND I. U. JAN

    2007-10-01

    Full Text Available The renal clearance and urinary excretion of ciprofloxacin were investigated in eight healthy female goats. In each animal, ciprofloxacin was administered intramuscularly at the rate of 5 mg/kg body weight. Following drug administration, blood and urine samples were collected at different time intervals and analyzed for ciprofloxacin and creatinine. High performance liquid chromatography (HPLC was used to determine the drug concentration in the plasma and urine. The value of diuresis after single administration of ciprofloxacin was 0.073 ± 0.014 ml/min/kg. Mean (± SE values for renal clearance of creatinine and ciprofloxacin were 1.870 ± 0.385 and 0.982 ± 0.166 ml/min/kg, respectively. The ratio between the renal clearance of ciprofloxacin and that of creatinine remained less than one, which was indicative of back diffusion. The mean (± SE value for the cumulative percent of ciprofloxacin dose excreted at 10 hours following its intramuscular administration was 13.03 ± 2.07. Based on these results, it was evident that besides glomerular filtration, renal handling of drug involved back diffusion also. It was concluded that in local goats glomerular filtration rate (GFR was lower than that reported for their foreign counterparts.

  11. Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.

    Science.gov (United States)

    Reddy, Kavya; Cusack, Corey L; Nnah, Israel C; Khayati, Khoosheh; Saqcena, Chaitali; Huynh, Tuong B; Noggle, Scott A; Ballabio, Andrea; Dobrowolski, Radek

    2016-03-01

    Attenuated auto-lysosomal system has been associated with Alzheimer disease (AD), yet all underlying molecular mechanisms leading to this impairment are unknown. We show that the amino acid sensing of mechanistic target of rapamycin complex 1 (mTORC1) is dysregulated in cells deficient in presenilin, a protein associated with AD. In these cells, mTORC1 is constitutively tethered to lysosomal membranes, unresponsive to starvation, and inhibitory to TFEB-mediated clearance due to a reduction in Sestrin2 expression. Normalization of Sestrin2 levels through overexpression or elevation of nuclear calcium rescued mTORC1 tethering and initiated clearance. While CLEAR network attenuation in vivo results in buildup of amyloid, phospho-Tau, and neurodegeneration, presenilin-knockout fibroblasts and iPSC-derived AD human neurons fail to effectively initiate autophagy. These results propose an altered mechanism for nutrient sensing in presenilin deficiency and underline an importance of clearance pathways in the onset of AD. PMID:26923592

  12. Effect of Guide Vane Clearance Gap on Francis Turbine Performance

    Directory of Open Access Journals (Sweden)

    Ravi Koirala

    2016-04-01

    Full Text Available Francis turbine guide vanes have pivoted support with external control mechanism, for conversion of pressure to kinetic energy and to direct them to runner vanes. This movement along the support is dependent on variation of load and flow (operating conditions. Small clearance gaps between facing plates and the upper and lower guide vane tips are available to aid this movement, through which leakage flow occurs. This secondary flow disturbs the main flow stream, resulting performance loss. Additionally, these increased horseshoe vortex, in presence of sand, when crosses through the gaps, both the surfaces are eroded. This causes further serious effect on performance and structural property by increasing gaps. This paper discusses the observation of the severity in hydropower plants and effect of clearance gaps on general performance of the Francis turbine through computational methods. It also relates the primary result with the empirical relation for leakage flow prediction. Additionally, a possible method to computationally estimate thickness depletion has also been presented. With increasing clearance gap, leakage increases, which lowers energy conversion and turbine efficiency along with larger secondary vortex.

  13. Technetium 99m mercaptoacetyltriglycine gamma camera clearance calculations: Methodological problems

    International Nuclear Information System (INIS)

    Major sources of errors in the gamma-camera methods for the calculation of renal clearance are the accuracy of background correction for obtaining the true renal time-activity curve and the validity of the externally recorded pre-cordial activity as an estimate of the plasmatic time-activity curve. With technetium 99m mercaptoacetyltriglycine (99mTc-MAG3), because of its high protein plasma binding, one could expect minimal extravascular diffusion and hence a more accurate externally detected plasmatic curve. The high extraction rate should reduce the influence of the background, but, on the other hand, the effect of hepatobiliary excretion on the calculation of renal clearance might be significant. Our results suggest that the hepatobiliary excretion of 99mTc-MAG3 does not influence the gamma-camera renal clearance determination, even in patients with low renal function. However, the pre-cordial curve does not reflect accurately the plasmatic disappearance curve; its calibration with a single plasma sample taken at the 20th min is responsible for significant errors, probably because of an unfavourable ratio between the intravascular and extravascular activities at the 20th min. (orig.)

  14. Fuzzy Behavior Modulation with Threshold Activation for Autonomous Vehicle Navigation

    Science.gov (United States)

    Tunstel, Edward

    2000-01-01

    This paper describes fuzzy logic techniques used in a hierarchical behavior-based architecture for robot navigation. An architectural feature for threshold activation of fuzzy-behaviors is emphasized, which is potentially useful for tuning navigation performance in real world applications. The target application is autonomous local navigation of a small planetary rover. Threshold activation of low-level navigation behaviors is the primary focus. A preliminary assessment of its impact on local navigation performance is provided based on computer simulations.

  15. Indoor navigation using Bluetooth Low Energy (BLE) beacons

    OpenAIRE

    Herrera Vargas, Milan

    2016-01-01

    The popularity of indoor navigation has significantly increased during the last decade. Nowadays, many studies aim to develop new indoor navigation systems and improve the accuracy of the already existing ones. Unfortunately, no definitive method for indoor navigation has been approved yet, which is why this type of systems are not as accessible as those used for outdoor navigation. The purpose of this thesis is to introduce the concept of indoor navigation and demonstrate how common elec...

  16. Numerical investigation of tip clearance effects on the performance of ducted propeller

    Science.gov (United States)

    Yongle, Ding; Baowei, Song; Peng, Wang

    2015-09-01

    Tip clearance loss is a limitation of the improvement of turbomachine performance. Previous studies show the Tip clearance loss is generated by the leakage flow through the tip clearance, and is roughly linearly proportional to the gap size. This study investigates the tip clearance effects on the performance of ducted propeller. The investigation was carried out by solving the Navier-Stokes equations with the commercial Computational Fluid Dynamic (CFD) code CFX14.5. These simulations were carried out to determine the underlying mechanisms of the tip clearance effects. The calculations were performed at three different chosen advance ratios. Simulation results showed that the tip loss slope was not linearly at high advance due to the reversed pressure at the leading edge. Three type of vortical structures were observed in the tip clearance at different clearance size.

  17. Numerical investigation of tip clearance effects on the performance of ducted propeller

    Directory of Open Access Journals (Sweden)

    Yongle Ding

    2015-09-01

    Full Text Available Tip clearance loss is a limitation of the improvement of turbomachine performance. Previous studies show the Tip clearance loss is generated by the leakage flow through the tip clearance, and is roughly linearly proportional to the gap size. This study investigates the tip clearance effects on the performance of ducted propeller. The investigation was carried out by solving the Navier-Stokes equations with the commercial Computational Fluid Dynamic (CFD code CFX14.5. These simulations were carried out to determine the underlying mechanisms of the tip clearance effects. The calculations were performed at three different chosen advance ratios. Simulation results showed that the tip loss slope was not linearly at high advance due to the reversed pressure at the leading edge. Three type of vortical structures were observed in the tip clearance at different clearance size.

  18. From translation to navigation of different discourses

    DEFF Research Database (Denmark)

    Livonen, Mirja; Sonnenwald, Diane H.

    1998-01-01

    We propose a model of the search term selection process based on our empirical study of professional searchers during the pre-online stage of the search process. The model characterizes the selection of search terms as the navigation of different discourses. Discourse refers to the ways of talking...... and thinking about a certain topic; there often exists multiple, diverse discourses on the same topic. When selecting search terms, searchers appear to navigate a variety of discourses, i.e., they view the topic of a client's search request from the perspective of multiple discourse communities, and...... the searchers' own search experience. Data further suggest that searchers navigate these discourses dynamically and have preferences for certain discourses. Conceptualizing the selection of search terms as a meeting place of different discourses provides new insights into the complex nature of the...

  19. Mobile Navigation for Sport’s Pilots

    Directory of Open Access Journals (Sweden)

    Dušan Fister

    2013-06-01

    Full Text Available Today, global object-positioning is accomplished very precisely by GPS satellite technology. Access to this information is provided globally by widespread mobile devices with integrated GPS receivers from everywhere also from airplane. This paper presents a mobile device using GPS receiver to be used by mobile navigation for sports pilots. In fact, the mobile navigation is a mobile application running on Android. Thus, the current position of the airplane is indicated on the GoogleMaps and compared with the planned direction of the flight by the pilot. In addition, this mobile application could also serve flight instructors when tracking student pilots by first independent flights. The proposed solution has shown in practice to be the cheapest substitute for expensive professional navigation devices.

  20. Cloud Absorption Radiometer Autonomous Navigation System - CANS

    Science.gov (United States)

    Kahle, Duncan; Gatebe, Charles; McCune, Bill; Hellwig, Dustan

    2013-01-01

    CAR (cloud absorption radiometer) acquires spatial reference data from host aircraft navigation systems. This poses various problems during CAR data reduction, including navigation data format, accuracy of position data, accuracy of airframe inertial data, and navigation data rate. Incorporating its own navigation system, which included GPS (Global Positioning System), roll axis inertia and rates, and three axis acceleration, CANS expedites data reduction and increases the accuracy of the CAR end data product. CANS provides a self-contained navigation system for the CAR, using inertial reference and GPS positional information. The intent of the software application was to correct the sensor with respect to aircraft roll in real time based upon inputs from a precision navigation sensor. In addition, the navigation information (including GPS position), attitude data, and sensor position details are all streamed to a remote system for recording and later analysis. CANS comprises a commercially available inertial navigation system with integral GPS capability (Attitude Heading Reference System AHRS) integrated into the CAR support structure and data system. The unit is attached to the bottom of the tripod support structure. The related GPS antenna is located on the P-3 radome immediately above the CAR. The AHRS unit provides a RS-232 data stream containing global position and inertial attitude and velocity data to the CAR, which is recorded concurrently with the CAR data. This independence from aircraft navigation input provides for position and inertial state data that accounts for very small changes in aircraft attitude and position, sensed at the CAR location as opposed to aircraft state sensors typically installed close to the aircraft center of gravity. More accurate positional data enables quicker CAR data reduction with better resolution. The CANS software operates in two modes: initialization/calibration and operational. In the initialization/calibration mode

  1. Foot mounted inertial system for pedestrian navigation

    International Nuclear Information System (INIS)

    This paper discusses algorithmic concepts, design and testing of a system based on a low-cost MEMS-based inertial measurement unit (IMU) and high-sensitivity global positioning system (HSGPS) receivers for seamless personal navigation in a GPS signal degraded environment. The system developed here is mounted on a pedestrian shoe/foot and uses measurements based on the dynamics experienced by the inertial sensors on the user's foot. The IMU measurements are processed through a conventional inertial navigation system (INS) algorithm and are then integrated with HSGPS receiver measurements and dynamics derived constraint measurements using a tightly coupled integration strategy. The ability of INS to bridge the navigation solution is evaluated through field tests conducted indoors and in severely signal degraded forest environments. The specific focus is on evaluating system performance under challenging GPS conditions

  2. Active-imaging-based underwater navigation

    Science.gov (United States)

    Monnin, David; Schmitt, Gwenaël.; Fischer, Colin; Laurenzis, Martin; Christnacher, Frank

    2015-10-01

    Global navigation satellite systems (GNSS) are widely used for the localization and the navigation of unmanned and remotely operated vehicles (ROV). In contrast to ground or aerial vehicles, GNSS cannot be employed for autonomous underwater vehicles (AUV) without the use of a communication link to the water surface, since satellite signals cannot be received underwater. However, underwater autonomous navigation is still possible using self-localization methods which determines the relative location of an AUV with respect to a reference location using inertial measurement units (IMU), depth sensors and even sometimes radar or sonar imaging. As an alternative or a complementary solution to common underwater reckoning techniques, we present the first results of a feasibility study of an active-imaging-based localization method which uses a range-gated active-imaging system and can yield radiometric and odometric information even in turbid water.

  3. Benchmark Framework for Mobile Robots Navigation Algorithms

    Directory of Open Access Journals (Sweden)

    Nelson David Muñoz-Ceballos

    2014-01-01

    Full Text Available Despite the wide variety of studies and research on mobile robot systems, performance metrics are not often examined. This makes difficult to establish an objective comparison of achievements. In this paper, the navigation of an autonomous mobile robot is evaluated. Several metrics are described. These metrics, collectively, provide an indication of navigation quality, useful for comparing and analyzing navigation algorithms of mobile robots. This method is suggested as an educational tool, which allows the student to optimize the algorithms quality, relating to important aspectsof science, technology and engineering teaching, as energy consumption, optimization and design.

  4. Website Optimization through Mining User Navigational Pattern

    CERN Document Server

    Biswal, Biswajit

    2008-01-01

    With the World Wide Web's ubiquity increase and the rapid development of various online businesses, the complexity of web sites grow. The analysis of web user's navigational pattern within a web site can provide useful information for server performance enhancements, restructuring a website and direct marketing in e-commerce etc. In this paper, an algorithm is proposed for mining such navigation patterns. The key insight is that users access information of interest and follow a certain path while navigating a web site. If they don't find it, they would backtrack and choose among the alternate paths till they reach the destination. The point they backtrack is the Intermediate Reference Location. Identifying such Intermediate locations and destinations out of the pattern will be the main endeavor in the rest of this report.

  5. Indoor waypoint navigation via magnetic anomalies.

    Science.gov (United States)

    Riehle, Timothy H; Anderson, Shane M; Lichter, Patrick A; Condon, John P; Sheikh, Suneel I; Hedin, Daniel S

    2011-01-01

    A wide assortment of technologies have been proposed to construct indoor navigation services for the blind and vision impaired. Proximity-based systems and multilateration systems have been successfully demonstrated and employed. Despite the technical success of these technologies, broad adoption has been limited due to their significant infrastructure and maintenance costs. An alternative approach utilizing the indoor magnetic signatures inherent to steel-frame buildings solves the infrastructure cost problem; in effect the existing building is the location system infrastructure. Although magnetic indoor navigation does not require the installation of dedicated hardware, the dedication of resources to produce precise survey maps of magnetic anomalies represents a further barrier to adoption. In the present work an alternative leader-follower form of waypoint-navigation system has been developed that works without surveyed magnetic maps of a site. Instead the wayfarer's magnetometer readings are compared to a pre-recorded magnetic "leader" trace containing magnetic data collected along a route and annotated with waypoint information. The goal of the navigation system is to correlate the follower's magnetometer data with the leader's to trigger audio cues at precise points along the route, thus providing location-based guidance to the user. The system should also provide early indications of off-route conditions. As part of the research effort a smartphone based application was created to record and annotate leader traces with audio and numeric data at waypoints of interest, and algorithms were developed to determine (1) when the follower reaches a waypoint and (2) when the follower goes off-route. A navigation system utilizing this technology would enable a low-cost indoor navigation system capable of replaying audio annotations at precise locations along pre-recorded routes. PMID:22255538

  6. Computer navigation versus fluoroscopy-guided navigation for thoracic pedicle screw placement: a meta-analysis.

    Science.gov (United States)

    Meng, Xiao-Tong; Guan, Xiao-Fei; Zhang, Hai-Long; He, Shi-Sheng

    2016-07-01

    Although application of intraoperative computer navigation technique had been integrated into placement of pedicle screws (PSs) in thoracic fusion for years, its security and practicability remain controversial. The aim of this study is to evaluate the accuracy, the operative time consumption, the amount of intraoperative blood loss, time of pedicle insertion and the incidence of complications of thoracic pedicle screw placement in patients with thoracic diseases such as scoliosis and kyphosis. Pubmed, Web of Knowledge, and Google scholar were searched to identify comparative studies of thoracic pedicle screw placement between intraoperative computer navigation and fluoroscopy-guided navigation. Outcomes of malposition rate, operative time consumption, insertion time, intraoperative blood loss, and the incidence of complications are evaluated. Fourteen articles including 1723 patients and 9019 PSs were identified matching inclusion criteria. The malposition rate was lower (RR: 0.33, 95 % CI: 0.28-0.38, P < 0.01) in computer navigation group than that in fluoroscopy-guided navigation group; the operative time was significantly longer [weighted mean difference (WMD) = 23.66, 95 % CI: 14.74-32.57, P < 0.01] in computer navigation group than that in fluoroscopy-guided navigation group. The time of insertion was shorter (WMD = -1.88, 95 % CI: -2.25- -1.52, P < 0.01) in computer navigation group than that in fluoroscopy-guided navigation group. The incidence of complications was lower (RR = 0. 23, 95 % CI: 0.12-0.46, P < 0.01) in computer navigation group than that in the other group. The intraoperative blood loss was fewer (WMD = -167.49, 95 % CI: -266.39- -68.58, P < 0.01) in computer navigation group than that in the other. In conclusion, the meta-analysis of thoracic pedicle screw placement studies clearly demonstrated lower malposition rate, less intraoperative blood loss, and fewer complications when using computer

  7. Navigating Art Therapy: A Therapists Companion

    OpenAIRE

    Jones, Kevin

    2010-01-01

    From Art-making as a Defence to Works of Art, this anthology will help you navigate your way through the ever growing world of art therapy. Art therapy is used in an increasing range of settings and is influenced by a range of disciplines, including psychotherapy, social psychiatry, social work and education. Navigating Art Therapy is an essential companion for both seasoned art therapists and those new to the field as it offers a comprehensive guide to key terms and concepts. With con...

  8. Navigering och styrning av ett autonomt markfordon

    OpenAIRE

    Johansson, Sixten

    2006-01-01

    I detta examensarbete har ett system för navigering och styrning av ett autonomt fordon implementerats. Syftet med detta arbete är att vidareutveckla fordonet som ska användas vid utvärdering av banplaneringsalgoritmer och studier av andra autonomifunktioner. Med hjälp av olika sensormodeller och sensorkonfigurationer går det även att utvärdera olika strategier för navigering. Arbetet har utförts utgående från en given plattform där fordonet endast använder sig av enkla ultraljudssensorer sam...

  9. Quartz angular rate sensor for automotive navigation

    Energy Technology Data Exchange (ETDEWEB)

    Nozoe, Toshiyuki; Ichinose, Toshihiko; Kawasaki, Syusaku; Hatanaka, Masakazu; Kuroda, Keisuke [Matsushita Electronic Components Co. Ltd. (Japan); Yamamoto, Kohji; Ogata, Motoki; Takeno, Shoichi [Fukui Matsushita Electric Co. Ltd. (Japan); Ishihara, Minoru; Ishii, Tadashi; Umeki, Mitoshi [Nihonn Denpa Kogyo Co. Ltd. (Japan)

    1999-07-01

    Many of the recent automotive navigation systems are introducing an angular rate sensor that detect vehicle yaw in their system due to the advantage of higher accuracy, in addition to a conventional GPS (Global Positioning System) and vehicle speed signals. Though there are a couple of other methods to get a vehicle direction information, the angular rate sensor is the most suitable device as a gyro in accuracy and reliability point of view. Matsushita developed a new compact angular rate sensor using quartz crystal for automotive navigation systems. The sensor's operation is based upon Coriolis force imposed on a vibrating quartz tuning fork. (orig.)

  10. Navigation and control of an autonomous vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Simon, A.; Soehnitz, I.; Becker, J.C.; Schumacher, W. [Technical Univ. Braunschweig (Germany). Inst. of Control Engineering

    2000-07-01

    This paper describes the fusion of sensor data for the navigation of an autonomous vehicle as well as two lateral control concepts to track the vehicle along a desired path. The fusion of navigation data is based on information provided by multiple object-detecting sensors. The object data is fused to increase the accuracy and to obtain the vehicle's state from the relative movement w.r.t. the objects. The presented lateral control methods are an LQG/H{sub 2}-design and an input-output linearizing algorithm. These control schemes were both implemented on a test vehicle. (orig.)

  11. Evolutionary strategy for achieving autonomous navigation

    Science.gov (United States)

    Gage, Douglas W.

    1999-01-01

    An approach is presented for the evolutionary development of supervised autonomous navigation capabilities for small 'backpackable' ground robots, in the context of a DARPA- sponsored program to provide robotic support to small units of dismounted warfighters. This development approach relies on the implementation of a baseline visual serving navigation capability, including tools to support operator oversight and override, which is then enhanced with semantically referenced commands and a mission scripting structure. As current and future machine perception techniques are able to automatically designate visual serving goal points, this approach should provide a natural evolutionary pathway to higher levels of autonomous operation and reduced requirements for operator intervention.

  12. Navigation: Bat orientation using Earth's magnetic field

    DEFF Research Database (Denmark)

    Holland, Richard A.; Thorup, Kasper; Vonhof, Maarten J.;

    2006-01-01

    Bats famously orientate at night by echolocation 1 , but this works over only a short range, and little is known about how they navigate over longer distances 2 . Here we show that the homing behaviour of Eptesicus fuscus, known as the big brown bat, can be altered by artificially shifting the...... Earth's magnetic field, indicating that these bats rely on a magnetic compass to return to their home roost. This finding adds to the impressive array of sensory abilities possessed by this animal for navigation in the dark....

  13. Diffusive chaos in navigation satellites orbits

    CERN Document Server

    Daquin, J; Tsiganis, K

    2016-01-01

    The navigation satellite constellations in medium-Earth orbit exist in a background of third-body secular resonances stemming from the perturbing gravitational effects of the Moon and the Sun. The resulting chaotic motions, emanating from the overlapping of neighboring resonant harmonics, induce especially strong perturbations on the orbital eccentricity, which can be transported to large values, thereby increasing the collision risk to the constellations and possibly leading to a proliferation of space debris. We show here that this transport is of a diffusive nature and we present representative diffusion maps that are useful in obtaining a global comprehension of the dynamical structure of the navigation satellite orbits.

  14. Neural encoding of objects relevant for navigation and resting state correlations with navigational ability.

    Science.gov (United States)

    Wegman, Joost; Janzen, Gabriele

    2011-12-01

    Objects along a route can help us to successfully navigate through our surroundings. Previous neuroimaging research has shown that the parahippocampal gyrus (PHG) distinguishes between objects that were previously encountered at navigationally relevant locations (decision points) and irrelevant locations (nondecision points) during simple object recognition. This study aimed at unraveling how this neural marking of objects relevant for navigation is established during learning and postlearning rest. Twenty-four participants were scanned using fMRI while they were viewing a route through a virtual environment. Eye movements were measured, and brain responses were time-locked to viewing each object. The PHG showed increased responses to decision point objects compared with nondecision point objects during route learning. We compared functional connectivity between the PHG and the rest of the brain in a resting state scan postlearning with such a scan prelearning. Results show that functional connectivity between the PHG and the hippocampus is positively related to participants' self-reported navigational ability. On the other hand, connectivity with the caudate nucleus correlated negatively with navigational ability. These results are in line with a distinction between egocentric and allocentric spatial representations in the caudate nucleus and the hippocampus, respectively. Our results thus suggest a relation between navigational ability and a neural preference for a specific type of spatial representation. Together, these results show that the PHG is immediately involved in the encoding of navigationally relevant object information. Furthermore, they provide insight into the neural correlates of individual differences in spatial ability. PMID:21671733

  15. Bio-inspired polarized skylight navigation: a review

    Science.gov (United States)

    Zhang, Xi; Wan, Yongqin; Li, Lijing

    2015-12-01

    The idea of using skylight polarization in navigation is learned from animals such as desert ants and honeybees. Various research groups have been working on the development of novel navigation systems inspired by polarized skylight. The research of background in polarized skylight navigation is introduced, and basic principle of the insects navigation is expatiated. Then, the research progress status at home and abroad in skylight polarization pattern, three bio-inspired polarized skylight navigation sensors and polarized skylight navigation are reviewed. Finally, the research focuses in the field of polarized skylight navigation are analyzed. At the same time, the trend of development and prospect in the future are predicted. It is believed that the review is helpful to people understand polarized skylight navigation and polarized skylight navigation sensors.

  16. Statement on the deficiencies of the regulations concerning the clearance of radioactive materials in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    The clearance regulations for radioactive materials in Germany were transferred from the radiation protection ordinance under atomic law into the conventional sector. These regulations were modified in 2011. The clearance regulations are based on the IAEA 10-micro Sv concept. The regulations do not include a collective dose limit, the binding dose limit has the character of a guiding value; the inherent safety of the clearance practice is not assured. The report discusses also the following topics: tendencies for extension of the clearance possibilities, problems of the allowed clearance paths, international regulations for the clearance of radioactive materials and the quantity structure for clearance in Germany.

  17. Tactile object exploration using cursor navigation sensors

    DEFF Research Database (Denmark)

    Kraft, Dirk; Bierbaum, Alexander; Kjaergaard, Morten; Ratkevicius, Jurgis; Kjær-Nielsen, Anders; Ryberg, Charlotte; Petersen, Henrik Gordon; Asfour, Tamim; Dillmann, Ruediger; Krüger, Norbert

    2009-01-01

    In robotic applications tactile sensor systems serve the purpose of localizing a contact point and measuring contact forces. We have investigated the applicability of a sensorial device commonly used in cursor navigation technology for tactile sensing in robotics. We show the potential of this...

  18. Navigation Architecture For A Space Mobile Network

    Science.gov (United States)

    Valdez, Jennifer E.; Ashman, Benjamin; Gramling, Cheryl; Heckler, Gregory W.; Carpenter, Russell

    2016-01-01

    The Tracking and Data Relay Satellite System (TDRSS) Augmentation Service for Satellites (TASS) is a proposed beacon service to provide a global, space-based GPS augmentation service based on the NASA Global Differential GPS (GDGPS) System. The TASS signal will be tied to the GPS time system and usable as an additional ranging and Doppler radiometric source. Additionally, it will provide data vital to autonomous navigation in the near Earth regime, including space weather information, TDRS ephemerides, Earth Orientation Parameters (EOP), and forward commanding capability. TASS benefits include enhancing situational awareness, enabling increased autonomy, and providing near real-time command access for user platforms. As NASA Headquarters Space Communication and Navigation Office (SCaN) begins to move away from a centralized network architecture and towards a Space Mobile Network (SMN) that allows for user initiated services, autonomous navigation will be a key part of such a system. This paper explores how a TASS beacon service enables the Space Mobile Networking paradigm, what a typical user platform would require, and provides an in-depth analysis of several navigation scenarios and operations concepts.

  19. Orchard navigation using derivative free Kalman filtering

    DEFF Research Database (Denmark)

    Hansen, Søren; Bayramoglu, Enis; Andersen, Jens Christian;

    2011-01-01

    This paper describes the use of derivative free filters for mobile robot localization and navigation in an orchard. The localization algorithm fuses odometry and gyro measurements with line features representing the surrounding fruit trees of the orchard. The line features are created on basis of...

  20. 46 CFR 120.420 - Navigation lights.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Navigation lights. 120.420 Section 120.420 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) SMALL PASSENGER VESSELS CARRYING MORE THAN 150 PASSENGERS OR WITH OVERNIGHT ACCOMMODATIONS FOR MORE THAN 49 PASSENGERS ELECTRICAL INSTALLATION...

  1. Navigating the Bio-Politics of Childhood

    Science.gov (United States)

    Lee, Nick; Motzkau, Johanna

    2011-01-01

    Childhood research has long shared a bio-political terrain with state agencies in which children figure primarily as "human futures". In the 20th century bio-social dualism helped to make that terrain navigable by researchers, but, as life processes increasingly become key sites of bio-political action, bio-social dualism is becoming less useful…

  2. Indoor Autonomous Airship Control and Navigation System

    OpenAIRE

    Fedorenko Roman; Krukhmalev Victor

    2016-01-01

    The paper presents an automatic control system for autonomous airship. The system is designed to organize autonomous flight of the mini-airship performing flight mission defined from ground control station. Structure, hardware and software implementation of indoor autonomous airship and its navigation and control system as well as experiment results are described.

  3. Indoor Autonomous Airship Control and Navigation System

    Directory of Open Access Journals (Sweden)

    Fedorenko Roman

    2016-01-01

    Full Text Available The paper presents an automatic control system for autonomous airship. The system is designed to organize autonomous flight of the mini-airship performing flight mission defined from ground control station. Structure, hardware and software implementation of indoor autonomous airship and its navigation and control system as well as experiment results are described.

  4. Spatial abstraction for autonomous robot navigation.

    Science.gov (United States)

    Epstein, Susan L; Aroor, Anoop; Evanusa, Matthew; Sklar, Elizabeth I; Parsons, Simon

    2015-09-01

    Optimal navigation for a simulated robot relies on a detailed map and explicit path planning, an approach problematic for real-world robots that are subject to noise and error. This paper reports on autonomous robots that rely on local spatial perception, learning, and commonsense rationales instead. Despite realistic actuator error, learned spatial abstractions form a model that supports effective travel. PMID:26227680

  5. Autonomous system for cross-country navigation

    Science.gov (United States)

    Stentz, Anthony; Brumitt, Barry L.; Coulter, R. C.; Kelly, Alonzo

    1993-05-01

    Autonomous cross-country navigation is essential for outdoor robots moving about in unstructured environments. Most existing systems use range sensors to determine the shape of the terrain, plan a trajectory that avoids obstacles, and then drive the trajectory. Performance has been limited by the range and accuracy of sensors, insufficient vehicle-terrain interaction models, and the availability of high-speed computers. As these elements improve, higher- speed navigation on rougher terrain becomes possible. We have developed a software system for autonomous navigation that provides for greater capability. The perception system supports a large braking distance by fusing multiple range images to build a map of the terrain in front of the vehicle. The system identifies range shadows and interpolates undersamples regions to account for rough terrain effects. The motion planner reduces computational complexity by investigating a minimum number of trajectories. Speeds along the trajectory are set to provide for dynamic stability. The entire system was tested in simulation, and a subset of the capability was demonstrated on a real vehicle. Results to date include a continuous 5.1 kilometer run across moderate terrain with obstacles. This paper begins with the applications, prior work, limitations, and current paradigms for autonomous cross-country navigation, and then describes our contribution to the area.

  6. Spatial Navigation in Preclinical Alzheimer's Disease.

    Science.gov (United States)

    Allison, Samantha L; Fagan, Anne M; Morris, John C; Head, Denise

    2016-02-01

    Although several previous studies have demonstrated navigational deficits in early-stage symptomatic Alzheimer's disease (AD), navigational abilities in preclinical AD have not been examined. The present investigation examined the effects of preclinical AD and early-stage symptomatic AD on spatial navigation performance. Performance on tasks of wayfinding and route learning in a virtual reality environment were examined. Comparisons were made across the following three groups: Clinically normal without preclinical AD (n = 42), clinically normal with preclinical AD (n = 13), and early-stage symptomatic AD (n = 16) groups. Preclinical AD was defined based on cerebrospinal fluid Aβ42 levels below 500 pg/ml. Preclinical AD was associated with deficits in the use of a wayfinding strategy, but not a route learning strategy. Moreover, post-hoc analyses indicated that wayfinding performance had moderate sensitivity and specificity. Results also confirmed early-stage symptomatic AD-related deficits in the use of both wayfinding and route learning strategies. The results of this study suggest that aspects of spatial navigation may be particularly sensitive at detecting the earliest cognitive deficits of AD. PMID:26967209

  7. Imaging, Navigation, and Robotics in Spine Surgery.

    Science.gov (United States)

    Johnson, Norbert

    2016-04-01

    Spinal technology involves imaging, navigation, and robotics-collectively known as "image-guided therapy." Imaging coupled with navigation enhances visualization of irregular anatomy, enabling less invasive procedures. With robotics surgeons can perform quicker and safer hand movements with increased accuracy. In the 1890s, X-rays were invented by Roentgen. The first piece of X-ray equipment, the Cryptoscope, would take an image for 15 minutes, with the surgeon placing his hand in front of the beam to guide calibration; radiation exposure for both surgeon and patient was extreme. In the 1950s, fluoroscopy (C-arm) was invented. In the 1970s, computer-assisted tomography (CAT), known as CAT scan, became available; magnetic resonance imaging had its beginnings in the 1980s, and in 1985, the first robotic surgery was performed to obtain a neurosurgical biopsy specimen. The concept of navigation was introduced in the 1990s, and today's niche products for navigation came onto the market in the 2000s. PMID:27015071

  8. Evaluation of navigation interfaces in virtual environments

    Science.gov (United States)

    Mestre, Daniel R.

    2014-02-01

    When users are immersed in cave-like virtual reality systems, navigational interfaces have to be used when the size of the virtual environment becomes larger than the physical extent of the cave floor. However, using navigation interfaces, physically static users experience self-motion (visually-induced vection). As a consequence, sensorial incoherence between vision (indicating self-motion) and other proprioceptive inputs (indicating immobility) can make them feel dizzy and disoriented. We tested, in two experimental studies, different locomotion interfaces. The objective was twofold: testing spatial learning and cybersickness. In a first experiment, using first-person navigation with a flystick ®, we tested the effect of sensorial aids, a spatialized sound or guiding arrows on the ground, attracting the user toward the goal of the navigation task. Results revealed that sensorial aids tended to impact negatively spatial learning. Moreover, subjects reported significant levels of cybersickness. In a second experiment, we tested whether such negative effects could be due to poorly controlled rotational motion during simulated self-motion. Subjects used a gamepad, in which rotational and translational displacements were independently controlled by two joysticks. Furthermore, we tested first- versus third-person navigation. No significant difference was observed between these two conditions. Overall, cybersickness tended to be lower, as compared to experiment 1, but the difference was not significant. Future research should evaluate further the hypothesis of the role of passively perceived optical flow in cybersickness, but manipulating the virtual environment'sperrot structure. It also seems that video-gaming experience might be involved in the user's sensitivity to cybersickness.

  9. SOIL QUALITY CHANGES FOLLOWING FOREST CLEARANCE IN BENGKULU, SUMATRA

    Directory of Open Access Journals (Sweden)

    I.P. HANDAYANI

    2004-01-01

    Full Text Available Intense destruction and degradation of tropical forests is recognized as one of the environmental threats and tragedies. These have increased the need to assess the effects of subsequent land-use following forest extraction on soil quality. Therefore, the objective of this study is to evaluate the impacts of land-use type on soil quality properties in Bengkulu Province, Sumatra. Soil samples were collected from adjacent sites including natural secondary forest, bare land, cultivated land and grassland. The results show that land-use following forest clearance lowered saturated hydraulic conductivity (85%, porosity (10.50%, soil water content at field capacity (34%,C organic (27%, N total (26%, inorganic N (37%, soil microbial biomass C (32%, mineralizable C (22%, and particulate organic matter (50%, but slightly increased water soluble organic C. Specific respiration activi ty rates increased about 14% in cultivated soils compared to natural forest soils, indicating greater C turnover per labile C pool in the form of soil microbial biomass, thus decreased biologically active soil organic matter. Forest conversion tends to reduce the C,ffg/Crer for all deforested sites. All of deforested areas relatively have infertile soil, with the worst case found in cultivated field. The C^g/Crd of cultivated field s was about 24% less than that of remnant fo rest (1.07. Grassland apparently mainta ins only slightly higher soil C levels than the bare land. On average, degradation index of so il following forest clearance was 35% with the highest deterioration occurred in the bare land (38%. Fallowing the fields by naturally growth of Imperata cylindrica for about 15 yr in abandoned land after 3-5 years of cultivation did not improve the soil quality. Moreover, forest clearance has an impact on soil quality as resulted in the loss of a physically protected organic matter and reduction in some labile C pools, thus declined biological activity at disturbed

  10. Retention and clearance of inhaled submicron carbon black particles.

    Science.gov (United States)

    Strom, K A; Johnson, J T; Chan, T L

    1989-01-01

    Carbon black aerosols were used as a probe of the pulmonary retention and clearance of submicron particles. Male Fischer rats (COBS CD) were exposed for 20 h/d, 7 d/wk for 1, 3, or 6 wk to either 7 +/- 2 mg/m3 carbon black or filtered air. The submicron aerosol (mass median aerodynamic diameter, MMAD, 0.24 microns) was generated with a Wright dust feed-cyclone system. Lung and hilar lymph node particle burdens were determined immediately following the exposure and at preselected intervals up to 1 yr postexposure. After 1-, 3-, and 6-wk exposures, the lung burdens were 1.1 +/- 0.1, 3.5 +/- 0.2, and 5.9 +/- 0.1 mg, respectively. One year after a 1-, 3-, or 6-wk exposure, 8%, 46%, and 61% of the initial lung burden remained in the lungs. Initially, the hilar lymph nodes contained 0.2%, 0.9%, and 2.0% of the lung burdens in the 3 exposure groups, respectively. At 1 yr postexposure, particle translocation from the lungs led to a rise in lymph node burdens to 1%, 21%, and 27% of the initial lung burden. The retention of carbon black in both the lungs and lymph nodes combined was 9%, 67%, and 89% for the 1-, 3-, and 6-wk exposed animals. Lung clearance was modeled as a compartmental system consisting of four lung compartments and a regional lymph node compartment. The results from the model are similar for carbon black and diesel engine exhaust particles. However, the compartmental kinetics of carbon black differed in two ways: the deposition efficiency in the alveolar region was lower than that for diesel exhaust particles, and there was earlier transport of particles to the regional lymph nodes. These results showed that when lung burdens reached 0.8 mg, lung clearance was decreased by 50% and lymphatic transport of insoluble particles was increased. PMID:2466129

  11. JAVAMIX : a tactical decision to evaluate minefield clearance plans

    OpenAIRE

    Paes Filho, Jose C.

    2001-01-01

    A Tactical Decision Aid (TDA) for mixed minefield clearance, JAVAMIX, was designed, developed and tested. The TDA uses a Monte Carlo Simulation and it is based on the Monte Carlo option of the TDA MIXER (Washburn, 1995). The JAVAMIX GUI allows the user to introduce different plans based on the sweep and resource types available and mine types expected. To clear the minefield the user is asked to choose a parameter file and to introduce a plan. Output tables are presented in a DOS window and p...

  12. Navigated Waterways of Louisiana, Geographic NAD83, LOSCO (1999) [navigated_waterways_LOSCO_1999

    Data.gov (United States)

    Louisiana Geographic Information Center — This is a line dataset of navigated waterways fitting the LOSCO definition: it has been traveled by vessels transporting 10,000 gallons of oil or fuel as determined...

  13. 33 CFR 2.36 - Navigable waters of the United States, navigable waters, and territorial waters.

    Science.gov (United States)

    2010-07-01

    ... GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL JURISDICTION Jurisdictional Terms § 2.36 Navigable waters... used in sections 311 and 312 of the Federal Water Pollution Control Act, as amended, 33 U.S.C. 1321...

  14. Wayfinding and Navigation for People with Disabilities Using Social Navigation Networks

    Directory of Open Access Journals (Sweden)

    Hassan A. Karimi

    2014-10-01

    Full Text Available To achieve safe and independent mobility, people usually depend on published information, prior experience, the knowledge of others, and/or technology to navigate unfamiliar outdoor and indoor environments. Today, due to advances in various technologies, wayfinding and navigation systems and services are commonplace and are accessible on desktop, laptop, and mobile devices. However, despite their popularity and widespread use, current wayfinding and navigation solutions often fail to address the needs of people with disabilities (PWDs. We argue that these shortcomings are primarily due to the ubiquity of the compute-centric approach adopted in these systems and services, where they do not benefit from the experience-centric approach. We propose that following a hybrid approach of combining experience-centric and compute-centric methods will overcome the shortcomings of current wayfinding and navigation solutions for PWDs.

  15. Lunar Navigator - A Miniature, Fully Autonomous, Lunar Navigation, Surveyor, and Range Finder System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Microcosm proposes to design and develop a fully autonomous Lunar Navigator based on our MicroMak miniature star sensor and a gravity gradiometer similar to one on...

  16. 77 FR 45991 - Regulated Navigation Area; Buzzard's Bay, MA; Navigable Waterways Within the First Coast Guard...

    Science.gov (United States)

    2012-08-02

    ...The Coast Guard announces the availability of a draft Environmental Assessment (EA) considering the reasonably foreseeable environmental impacts and socioeconomic effects of implementing a Regulated Navigation Area in Buzzard's Bay, MA. We request your comments on the draft...

  17. Lunar Navigator - A Miniature, Fully Autonomous, Lunar Navigation, Surveyor, and Range Finder System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Microcosm will use existing hardware and software from related programs to create a prototype Lunar Navigation Sensor (LNS) early in Phase II, such that most of the...

  18. Spinal navigation in combination with intraoperative computed tomography; Spinale Navigation in Kombination mit der intraoperativen Computertomographie

    Energy Technology Data Exchange (ETDEWEB)

    Haberland, N.; Ebmeier, K.; Hliscs, R.; Grunewald, J.P.; Kalff, R.L. [Neurochirurgische Klinik und Poliklinik, Klinikum der Friedrich-Schiller-Univ. Jena (Germany)

    2000-02-01

    Assisted by the mobile Tomoscan M CT system, titanium pedicle screw placement markers can be implanted into the vertebral segments prior to CT data acquisition for surgical navigation. This approach significantly enhances the spinal navigation accuracy. (orig./CB) [German] Mit Hilfe des mobilen CT-Systems Tomoscan M koennen Titanschraubmarker vor der CT-Datenakquisition in die Wirbelsegmente implantiert werden. Das fuehrt zu wesentlich hoeherer Applikationsgenauigkeit am Zielpunkt. (orig.)

  19. Zasnova mobilne multimodalne komunikacijske naprave - osebni navigator: The design of mobile multimodal communication device - personal navigator:

    OpenAIRE

    Horvat, Bogomir; Horvat, Boštjan; Kačič, Zdravko; Kotnik, Bojan; Kramberger, Iztok; Rotovnik, Tomaž

    2001-01-01

    In today's world there are increasing demands for products that would enable a palette of services and would be portable, light, small and ergonomically designed. Their handling, however, should be as simple as possible, e.g. voice driven. Demands like that have brought about an integration of different technologies. The concept of the device which we describe in this article is called personal navigator. Personal navigator presents a multimodal communication device. It enables the user visua...

  20. Clearance of 99mTc-DTPA and experimentally increased alveolar surfactant content

    International Nuclear Information System (INIS)

    The authors measured clearance of 99mTc-labeled diethylenetriamine pentaacetic acid (99mTc-DTPA) in rabbits with experimentally increased alveolar surfactant content. In one group of animals, surfactant production was increased by treatment with ambroxol, and another group of animals was treated with tracheal instillation of natural surfactant. A group of untreated control animals and animals treated with instillation of saline were also studied. Clearance was measured during standard conditions of mechanical ventilation and during ventilation with large tidal volumes. In ambroxol- and surfactant-treated groups, clearance rate was reduced compared with untreated control animals. In contrast, clearance rate increased after saline instillation. The differences were observed at both modes of ventilation. The findings indicate that the pulmonary surfactant system is a rate-limiting factor for the clearance of 99mTc-DTPA and that the volume dependence of clearance is not explained by stretching of the alveolar wall only. 28 refs., 2 figs., 1 tab

  1. Investigation into the effect of fenoterol on mucociliary clearance in patients with chronic bronchitis

    International Nuclear Information System (INIS)

    We investigated the effects of fenoterol, a selective β2 adrenoceptor stimulant, on mucociliary clearance in 12 patients with chronic bronchitis. Mucociliary clearance was measured with a scintillation camera after inhalation of a 99mTc labeled aerosol. Fenoterol was administered one h after acquisition commenced and imaging was maintained for a further two h. Three regions of interest (ROI) were selected over each lung to generate time activity curves. Corrections for decay, alveolar deposition (using 24 h image), cough and movement of activity through each ROI were carried out. An exponential function was fitted to the clearance curves to determine clearance rates. The increase in percentage clearance after fenoterol administration for the left and right whole lung ROI was 35% and 36% per h respectively (P = 0.006 and 0.020). Fenoterol enhances cilial clearance in chronic bronchitis patients. (orig.)

  2. Science Benefits of Onboard Spacecraft Navigation

    Science.gov (United States)

    Cangahuala, Al; Bhaskaran, Shyam; Owen, Bill

    2012-01-01

    Primitive bodies (asteroids and comets), which have remained relatively unaltered since their formation, are important targets for scientific missions that seek to understand the evolution of the solar system. Often the first step is to fly by these bodies with robotic spacecraft. The key to maximizing data returns from these flybys is to determine the spacecraft trajectory relative to the target body-in short, navigate the spacecraft- with sufficient accuracy so that the target is guaranteed to be in the instruments' field of view. The most powerful navigation data in these scenarios are images taken by the spacecraft of the target against a known star field (onboard astrometry). Traditionally, the relative trajectory of the spacecraft must be estimated hours to days in advance using images collected by the spacecraft. This is because of (1)!the long round-trip light times between the spacecraft and the Earth and (2)!the time needed to downlink and process navigation data on the ground, make decisions based on the result, and build and uplink instrument pointing sequences from the results. The light time and processing time compromise navigation accuracy considerably, because there is not enough time to use more accurate data collected closer to the target-such data are more accurate because the angular capability of the onboard astrometry is essentially constant as the distance to the target decreases, resulting in better "plane-of- sky" knowledge of the target. Excellent examples of these timing limitations are high-speed comet encounters. Comets are difficult to observe up close; their orbits often limit scientists to brief, rapid flybys, and their coma further restricts viewers from seeing the nucleus in any detail, unless they can view the nucleus at close range. Comet nuclei details are typically discernable for much shorter durations than the roundtrip light time to Earth, so robotic spacecraft must be able to perform onboard navigation. This onboard

  3. Measurement of single kidney contrast media clearance by multiphasic spiral computed tomography: preliminary results

    International Nuclear Information System (INIS)

    Objective. We present preliminary results of a new method (hereinafter called 'CT-clearance') to measure single kidney contrast media clearance by performing multiphasic helical CT of the kidneys. CT-clearance was calculated according to an extension of the Patlak-Plot. In contrast to prior investigators, who repeatedly measured a single slice, this method makes it possible to calculate single kidney clearance from at least three spiral CTs, utilizing the whole kidney volume. Methods. Spiral CT of the kidneys was performed unenhanced and about 30 and 100 s after administration of about 120 ml iopromide. Sum-density of the whole kidneys and aortic density was calculated from this data. Using this data, renal clearance of contrast media was calculated by CT-clearance in 29 patients. As reference, Serum-clearance was calculated in 24 patients by application of a modified one-exponential slope model. Information on the relative kidney function was gained by renal scintigraphy with Tc99m-MAG-3 or Tc99m-DMSA in 29 patients. Results. Linear regression analysis revealed a correlation coefficient of CT-clearance with Serum-clearance of r=0.78 with Cl (CT) [ml/min]=22.2+1.03 * Cl (serum), n=24. Linear regression of the relative kidney function (rkf) of the right kidney calculated by CT-clearance compared to scintigraphy results provided a correlation coefficient r=0.89 with rkf(CT)[%]=18.6+0.58 * rkf(scintigraphy), n=29. Conclusion. The obtained results of contrast media clearance measured by CT-clearance are in the physiological range of the parameter. Future studies should be performed to improve the methodology with the aim of higher accuracy. More specifically, better determination of the aortic density curve might improve the accuracy

  4. A simple method for the verification of clearance levels for non-radioactive solid waste

    International Nuclear Information System (INIS)

    ANSTO's radiopharmaceutical production laboratories generate 25 m3 of solid waste per month. Most of this waste is not radioactive. Up until recently the non-radioactive waste was cleared from the controlled area and stored for 10 halflives prior to disposal as normal solid refuse. To eliminate the storage and ''double handling'' of the large quantities of non-radioactive waste a simple clearance method was devised to allow direct disposal. This paper describes how clearance levels were determined. Here the term ''clearance level'' is used as a general term for the release of material regardless of whether it was previously subject to regulatory control. This contrasts with the IAEA definition of a clearance level and highlights a potential problem with the implementation of exemption levels to keep material out of regulatory control and the use of clearance levels to allow removal of materials from regulatory control. Several common hand held contamination monitors were tested to determine their limits of detection and ability to meet these clearance levels. The clearance method includes waste segregation and size limitation features to ensure the waste is monitored in a consistent manner, compatible with the limits of detection. The clearance levels achieved were subsequently found to be compatible with some of the unconditional clearance levels in IAEA-TECDOC-855 and the measurement method also meets the required features of that document. The ANSTO non-radioactive waste clearance system has been in operation for more than 12 months and has proved simple and effective to operate. Approximately 12m3 of the solid waste is now been treated directly as normal solid refuse. This paper describes the ANSTO clearance system, the contamination monitor tests and details practical problems associated with the direct monitoring of solid waste, including averaging of the activity in the package. The paper also briefly highlights the potential problem with the use of exempted

  5. Vest Chest Physiotherapy Airway Clearance is Associated with Nitric Oxide Metabolism

    OpenAIRE

    Sisson, Joseph H.; Wyatt, Todd A.; Pavlik, Jacqueline A.; Pawanjit S. Sarna; Murphy, Peter J

    2013-01-01

    Background. Vest chest physiotherapy (VCPT) enhances airway clearance in cystic fibrosis (CF) by an unknown mechanism. Because cilia are sensitive to nitric oxide (NO), we hypothesized that VCPT enhances clearance by changing NO metabolism. Methods. Both normal subjects and stable CF subjects had pre- and post-VCPT airway clearance assessed using nasal saccharin transit time (NSTT) followed by a collection of exhaled breath condensate (EBC) analyzed for NO metabolites (NO x ). Results. VCPT s...

  6. Spinal navigation in combination with intraoperative computed tomography

    International Nuclear Information System (INIS)

    Assisted by the mobile Tomoscan M CT system, titanium pedicle screw placement markers can be implanted into the vertebral segments prior to CT data acquisition for surgical navigation. This approach significantly enhances the spinal navigation accuracy. (orig./CB)

  7. LiAISON: Linked, Autonomous Interplanetary Satellite Orbit Navigation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — A new navigation technique known as LiAISON (Linked Autonomous Interplanetary Satellite Orbit Navigation) may be used to propel the benefits of GPS to new orbits,...

  8. Effects of active navigation on object recognition in virtual environments.

    Science.gov (United States)

    Hahm, Jinsun; Lee, Kanghee; Lim, Seung-Lark; Kim, Sei-Young; Kim, Hyun-Taek; Lee, Jang-Han

    2007-04-01

    We investigated the importance and efficiency of active and passive exploration on the recognition of objects in a variety of virtual environments (VEs). In this study, 54 participants were randomly allocated into one of active and passive navigation conditions. Active navigation was performed by allowing participants to self-pace and control their own navigation, but passive navigation was conducted by forced navigation. After navigating VEs, participants were asked to recognize the objects that had been in the VEs. Active navigation condition had a significantly higher percentage of hit responses (t (52) = 4.000, p object recognition than the passive condition. These results suggest that active navigation plays an important role in spatial cognition as well as providing an explanation for the efficiency of learning in a 3D-based program. PMID:17474852

  9. Complementary terrain/single beacon-based AUV navigation

    Digital Repository Service at National Institute of Oceanography (India)

    Maurya, P.; Curado, T.F.; António, P.

    This paper describes work done towards the development of advanced geophysical-based navigation systems for autonomous underwater vehicles (AUVs). The specific problem that we tackle is that of combining terrain-aided navigation (TAN) with single...

  10. Enhanced clearance of lactic dehydrogenase-5 in severe combined immunodeficiency (SCID) mice: effect of lactic dehydrogenase virus on enzyme clearance.

    OpenAIRE

    Hayashi, T.; Ozaki, M.; Mori, I; Saito, M; Itoh, T.; Yamamoto, H.

    1992-01-01

    The lactic dehydrogenase (LDH) level in plasma and the clearance of LDH in C.B-17 scid (severe combined immunodeficiency; SCID) mice were compared with those in C.B-17 or BALB/cCrSlc mice with or without lactic dehydrogenase virus (LDV) infection. The resting enzyme level in SCID mice showed little difference from that in C.B-17 or BALB/cCrSlc mice. The degree of increased plasma LDH level in SCID mice was lower than that in C.B-17 and BALB/cCrSlc mice after LDV infection. To assess the mecha...

  11. Bacterial clearance in the intact and regenerating liver

    International Nuclear Information System (INIS)

    The Kupffer cells in the liver play an important role in reticuloendothelial system (RES) function by clearing particulate matter and bacteria from the blood stream. While hepatocyte regeneration and function have been extensively studied following partial hepatectomy, little information is available concerning RES function in the regenerating liver. This study investigates hepatic RES function by evaluating bacterial clearance (live E. coli) in the intact and regenerating liver. Thirty-four young male Sprague Dawley rats were studied. Twenty-two animals underwent a standard 70% partial hepatectomy using ligature technique and 12 had a sham operation. Both groups of rats received 10(9) organism of 35S labeled E coli, intravenously at 24 hours, 72 hours, 2 1/2 weeks, and 6 weeks postoperatively. Rats were killed 10 minutes following injection and liver, lung, spleen, and kidney harvested, fixed, and radioactivity was determined using a scintillation spectrometer interfaced with a micro-computer counting the 35S radiolabel. The total organ count of trapped bacteria in liver in partially hepatectomized rats was lower than intact controls at 24 hours, but was similar at 72 hours, 2 1/2 weeks, and 6 weeks. Partial hepatectomy increased the amount of bacterial trapping in the lung at 24 hours and 72 hours and returned to normal at 2 1/2 weeks and 6 weeks. Splenic activity was increased following hepatectomy at 2 1/2 weeks. Renal clearance was increased at 72 hours and 2 1/2 weeks

  12. Radionuclide quantification of oropharyngeal clearance with and without pharyngitis

    Energy Technology Data Exchange (ETDEWEB)

    Robbins, P.S.; Siegel, J.A.; Maurer, A.H.; Schachtel, B.P.; Malmud, L.S.

    1984-01-01

    The purpose of this study was to evaluate a new radionuclide method for quantifying oropharyngeal clearance (C) in 10 otherwise normal patients with and without pharyngitis (PH). Patients with objective evidence of PH initially swallowed 10 ml of water mixed with 1 mCi Tc-99m sulfur colloid and then performed a dry swallow each 15 seconds. This was repeated 1-4 weeks later when there was no evidence of pharyngitis (NP). Images were acquired using a high sensitivity collimator for 0.1 sec/image for 30 sec and 15 sec/image for an additional 270 sec. Time activity curves generated from a region of interest over the oropharynx were fit to a biexponential function, C = Ae/sup -k/1/sup t/ + Be/sup -k/2/sup t/; where A and B are the percent of activity clearing with fast and slow components, k/sub 1/, and k/sub 2/, respectively, with half times 0.693/k/sub l,2/. The T1/2 for the slow component was reproducible for PH and NP. The fast component was slightly prolonged with PH, but not to statistical significance (p>.2). The authors conclude that a biexponential model of clearance may be used to quantify oropharyngeal function, for patients with normal and abnormal swallowing.

  13. Two-phase deep-lung clearance in man

    International Nuclear Information System (INIS)

    For toxicological as well as physiological considerations, it is important to determine whether the long-term clearance of particles from the lungs of man takes place in more than one temporal subphase. Although long-term retention can be characterized with a single exponential, the existence of two distinct components would significantly alter estimates of overall residence times and hence potential effects of inhaled particulates. Physiological interpretations of the mechanisms of long-term particle clearance depend on the identification and quantification of such temporal subphases. A highly sensitive whole-body counter was used to measure the long-term retention of inhaled particles in man. After inhalation of 85Sr, lung retention was monitored in eight volunteers for periods ranging from 197 to 399 days. Their pulmonary-function values fell within normal limits, and they reported no symptoms of lung disease. Four of the individuals had never smoked, and four had not smoked for a minimum of 5 years. Single exponential representation half-times for the long-term retention were comparable between the two groups and were combined to give a mean half-time of 197 +- 32 days

  14. Reduction in slow intercompartmental clearance of urea during dialysis

    International Nuclear Information System (INIS)

    The kinetics of urea and inulin were analyzed in five anesthetized dogs during sequential 2-hour periods before, during, and after hemodialysis. The distribution of both compounds after simultaneous intravenous injection was characterized by three-compartment models, and the total volumes of urea (0.66 +/- 0.05 L/kg) and inulin (0.19 +/- 0.01 L/kg) distribution were similar to expected values for total body water and extravascular space, respectively. Intercompartmental clearances calculated before dialysis were used to estimate blood flows to the fast and slow equilibrating compartments. In agreement with previous results, the sum of these flows was similar to cardiac output, averaging 101% of cardiac output measured before dialysis (range 72% to 135%). Dialysis was accompanied by reductions in the slow intercompartmental clearances of urea (81%) and inulin (47%), which reflected a 90% attenuation in blood flow supplying the slow equilibrating compartments. This was estimated to result in a 10% average reduction in the efficiency with which urea was removed by dialysis (range 2.0% to 16.4%). Mean arterial pressure fell by less than 5% during dialysis, but total peripheral resistance increased by 47% and cardiac output fell by 35%. In the postdialysis period, total peripheral resistance and cardiac output returned toward predialysis values, but blood flow to the slow equilibrating peripheral compartment was still reduced by 80%. These changes parallel activation of the renin-angiotensin system, but further studies are required to establish causality

  15. Clearances of solid waste uranium by using gamma spectrometry

    International Nuclear Information System (INIS)

    Clearances of contaminated materials arising from desmantling or decommissioning must be provided with the result of measurement of radionuclide content in such materials. In this research, direct measurement of uranium in solid waste for a clearance requirement had been developed by using gamma spectrometric with HPGe detector. The measurement method was developed based on 1001 keV gamma energy of Pa-234m considering a self absorption, detector characteristic, background level factors. For validation purpose, this method was compared with a neutron activation analysis (NAA) techniques. Efficiency for 1001 keV of Pa-234m was 0,0991– 0,1369 cps/Bq on density of 0,51–1,81 g/cm3 with a minimum detectable level of 8–10 Bq/kg. This method was useful for high concentration of U-238 with a precision in acceptance criteria P < 1% and the gamma spectrometer showed a high performance with a value Zscore <1. (author)

  16. Quantification of clearance and creep in acetabular wear measurements

    Science.gov (United States)

    Gregory, Thomas; Vandenbussche, Eric

    2016-01-01

    Background This study aimed to measure femoral head penetration before occurrence of real wear, and to quantify the portions attributable respectively to clearance and plastic deformations in various acetabular designs. Methods We analyzed CT scans from 15 patients at ‘day five’ after total hip arthroplasty (THA). All patients received Exafit® femoral stems and 28 mm heads: 5 patients had cemented Durasul® all-PE cups, 5 patients had un-cemented Allofit® metal-backed cups, and 5 patients had un-cemented Stafit® dual-mobility cups. We also analyzed CT scans of samples of the three head-cup combinations to compare in vivo and in vitro measurements. Results The mean femoral head penetration measured on ‘day five’ was lower for all-PE cups (0.196 mm) than for metal-backed cups (0.551 mm) and dual-mobility cups (0.634 mm). Conclusions The present study indicates that isolated measurements of femoral head penetration include 0.15–0.46 mm of radial clearance and 0.05–0.27 mm of creep, and confirms that the majority of so-called bedding-in observed in the first post-operative months is not entirely due to wear. PMID:27162781

  17. 123I-IMP clearance of the lung in pneumoconiosis

    International Nuclear Information System (INIS)

    We studied 123I-IMP lung clearance on 10 cases of pneumoconiosis and compared it with the data of 5 non-smoking young adults. After the venous injection of 111 MBq of 123I-IMP we collected the lung dynamic data using 1 frame/10 sec for 10 minutes and 1 frame/min for following 40 minutes. The time activity curve after the injection of 123I-IMP was obtained as follows: C(t)=A1e-k1t+A2e-k2t (k1, k2: slopes of the exponential component at the early and delayed phase). The 123I-IMP clearance was delayed in the patients group especially on the early phase and the k1 was lower than that of the normal group. Our results indicate that the pulmonary blood flow of the patients with pneumoconiosis decreased because of the advanced fibrotic change. This dynamic analysis may prove useful for the evaluation of the pneumoconiosis objectively and quantitatively. (author)

  18. The clearance of oily vehicles following intramuscular and subcutaneous injections in rabbits

    International Nuclear Information System (INIS)

    [131I]-Iodinated oils were administered to rabbits by intramuscular and subcutaneous injection. Clearance of [131I]-iodinated oils from the site of injection was monitored by gamma-scintigraphy. Clearance rates were found to be independent of the site of injection. The volume of injection had no effect on the clearance rate of [131I]-iodinated ethyl oleate when given intramuscularly. Lymphatic absorption did not appear to make a major contribution to the clearance of [131I]-iodinated oils from either site of injection. (Auth.)

  19. 76 FR 27742 - Agency Information Collection Activities: Requests for Comments; Clearance of Renewed Approval of...

    Science.gov (United States)

    2011-05-12

    ... consolidation under a single OMB control number. DATES: Written comments should be submitted by July 11, 2011..., 2011. Carla Scott, FAA Information Collection Clearance Officer, IT Enterprises Business...

  20. Exploring the influential factors in incident clearance time: Disentangling causation from self-selection bias.

    Science.gov (United States)

    Ding, Chuan; Ma, Xiaolei; Wang, Yinhai; Wang, Yunpeng

    2015-12-01

    Understanding the relationships between influential factors and incident clearance time is crucial to make effective countermeasures for incident management agencies. Although there have been a certain number of achievements on incident clearance time modeling, limited effort is made to investigate the relative role of incident response time and its self-selection in influencing the clearance time. To fill this gap, this study uses the endogenous switching model to explore the influential factors in incident clearance time, and aims to disentangle causation from self-selection bias caused by response process. Under the joint two-stage model framework, the binary probit model and switching regression model are formulated for both incident response time and clearance time, respectively. Based on the freeway incident data collected in Washington State, full information maximum likelihood (FIML) method is utilized to estimate the endogenous switching model parameters. Significant factors affecting incident response time and clearance time can be identified, including incident, temporal, geographical, environmental, traffic and operational attributes. The estimate results reveal the influential effects of incident, temporal, geographical, environmental, traffic and operational factors on incident response time and clearance time. In addition, the causality of incident response time itself and its self-selection correction on incident clearance time are found to be indispensable. These findings suggest that the causal effect of response time on incident clearance time will be overestimated if the self-selection bias is not considered. PMID:26373988

  1. Clearance rate of Mytilus edulis (L.) as a function of current velocity and mussel aggregation

    DEFF Research Database (Denmark)

    Nielsen, Pernille; Vismann, Bent

    2014-01-01

    The aim of the current study was to investigate the effect of water current velocities on the clearance rate of Mytilus edulis when different numbers of mussels were used in the experiments. An automatic setup, which controlled and monitored the algal concentration continually, was used to measure...... the effect of increasing current velocity (0.05-1.4 m/sec) on the M. edulis clearance rate. Clearance rate measurements were performed under constant food concentrations of 3,000 cells/mL of Rhodomonas salina on either 3 mussels or 20 mussels. We found that the clearance rate of 20 mussels was...

  2. Clearance of glucose and sucrose from the saliva of human subjects.

    Science.gov (United States)

    Sreebny, L M; Chatterjee, R; Kleinberg, I

    1985-01-01

    The ability of 20 healthy people to clear test solutions of sucrose (0.73 M) and glucose (1.4 M) from the mouth was examined. Both sugars were cleared within 20 min in a two-step manner. Rapid clearance occurred between 0 and 6 min; much slower clearance occurred thereafter. It took 7.2 min with glucose and 6.3 min with sucrose for the saliva-sugar concentration to fall to 1 mg/ml. Salivary flow, stimulated during sugar exposure, decreased in a two-step pattern similar to sugar clearance. Evidently, clearance was dependent on the rate of flow of saliva which took about 1 h to return to its resting flow level. Comparison of the pattern of sugar clearance to the Stephan curve (the rapid pH fall followed by a slow pH rise seen after rinsing with sugar solutions) indicated that the pH-fall phase of the curve occurs during the initial period of rapid sugar clearance and salivary flow, and the pH-rise phase occurs during the subsequent period of slower clearance and slow saliva flow. Comparison with the data of Swenander-Lanke (1957) [Acta odont. scand. 15, 3-156], indicated that the clearance of sugar solutions also reflects the clearance of sugar-containing solid foods from the mouth. PMID:3857898

  3. Whole body and regional clearances of noradrenaline and adrenaline in man

    DEFF Research Database (Denmark)

    Christensen, N J; Galbo, H; Gjerris, A;

    1984-01-01

    The whole body clearance of noradrenaline (NA) was measured in seven patients pre- and postoperatively. L-3H-NA was infused intravenously for 90 min and steady-state concentrations of L-3H-NA were measured in both arterial and peripheral venous blood. Preoperatively, in the resting supine position...... uptake of NA, since we found no correlation between clearance values based on venous and arterial sampling. In other experiments we measured the influence of physical exercise in young healthy subjects on the clearance rate of plasma adrenaline (A). The clearance of A, which at rest averaged 1.9 l...

  4. Olfaction Contributes to Pelagic Navigation in a Coastal Shark

    OpenAIRE

    Nosal, Andrew P.; Chao, Yi; Farrara, John D.; Chai, Fei; Hastings, Philip A.

    2016-01-01

    How animals navigate the constantly moving and visually uniform pelagic realm, often along straight paths between distant sites, is an enduring mystery. The mechanisms enabling pelagic navigation in cartilaginous fishes are particularly understudied. We used shoreward navigation by leopard sharks (Triakis semifasciata) as a model system to test whether olfaction contributes to pelagic navigation. Leopard sharks were captured alongshore, transported 9 km offshore, released, and acoustically tr...

  5. Hybrid Navigation using Sensor Fusion in Hand-Held Devices

    OpenAIRE

    Calero Scanlan, David

    2013-01-01

    This thesis analyses the performance that can be obtained in navigation applications by using the camera and sensors embedded in a mobile phone (and GPS when available). The project includes the development of image processing algorithms to extract useful observations for navigation. Navigation is based on the determination of the trajectory, ie, time, position, velocity and altitude. For a good navigation experience a period of calibration and characterization of embedded mobile sensors such...

  6. INDOOR POSITIONING AND NAVIGATION BASED ON CONTROL SPHERECAL PANORAMIC IMAGES

    OpenAIRE

    Huang, Tsung-Che; Tseng, Yi-Hsing

    2016-01-01

    Continuous indoor and outdoor positioning and navigation is the goal to achieve in the field of mobile mapping technology. However, accuracy of positioning and navigation will be largely degraded in indoor or occluded areas, due to receiving weak or less GNSS signals. Targeting the need of high accuracy indoor and outdoor positioning and navigation for mobile mapping applications, the objective of this study is to develop a novel method of indoor positioning and navigation with the use of sph...

  7. Effectiveness of small barriers as means to reduce clearance distances

    Energy Technology Data Exchange (ETDEWEB)

    Tchouvelev, Andrei V.; Cheng, Zhong [A.V.Tchouvelev and Associates, 6591 Spinnaker Circle, Mississauga, Ont. (Canada); Agranat, Vladimir M. [Hydrogenics Corp., 5985 McLaughlin Road, Mississauga, Ont. (Canada); Zhubrin, Serguei V. [Flowsolve Limited, 130 Arthur Road, London SW19 8AA (United Kingdom)

    2007-07-15

    Hydrogen clearance or safety distance can be defined as the minimum distance between a hydrogen leak source and surrounding equipment, property or personnel beyond which the risk to the said recipients associated with existing hydrogen hazards is deemed acceptable. The same principal is applied to determine clearances to ignition sources and air intakes only the criteria in this case are the risk of ignition or the risk of intaking a flammable mixture. The study of effects of small barriers as means to reduce clearance distances for compressed hydrogen releases is important for the development of installation codes and risk mitigation requirements. In this paper, computational fluid dynamics (CFD) modeling techniques were applied to the numerical simulation of the effects of a protective wall of 1 m by 1 m on reducing the size of hydrogen cloud. The protective wall was 1 m away from a 70 MPa (700 bar) 60 L tank, from which an incidental hydrogen release impinged horizontally onto the wall, causing a complicated 3D dispersion of hydrogen cloud. In-house CFD codes first accurately estimated the non-linear hydrogen mass release rate decreasing with time. Then the effects of the wall on the propagation speed of the hydrogen cloud moving behind the wall were investigated using the PHOENICS software package, provided with both the ideal gas law and the real gas law expressed by the Abel-Nobel equation of state (AN-EOS). The distributions of lower flammability limit (LFL) and 50% of LFL hydrogen clouds were described in detail based on the numerical results. It was found that the 50% of LFL hydrogen clouds (2% vol) could propagate behind the wall in less than 0.2 s after the onset of the release. The horizontal extents corresponding to 50% of LFL hydrogen cloud on the central vertical plane are 9.6 m at 5 s when they are predicted using the ideal gas law. When using the real gas law, the predicted extents decrease to 6.3 m at 5 s. The ideal gas law significantly

  8. 33 CFR 64.31 - Determination of hazard to navigation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Determination of hazard to... Provisions § 64.31 Determination of hazard to navigation. In determining whether an obstruction is a hazard... vessel incidents involving the obstruction; and (k) Whether the obstruction is defined as a hazard...

  9. Private Graphs - Access Rights on Graphs for Seamless Navigation

    Science.gov (United States)

    Dorner, W.; Hau, F.; Pagany, R.

    2016-06-01

    After the success of GNSS (Global Navigational Satellite Systems) and navigation services for public streets, indoor seems to be the next big development in navigational services, relying on RTLS - Real Time Locating Services (e.g. WIFI) and allowing seamless navigation. In contrast to navigation and routing services on public streets, seamless navigation will cause an additional challenge: how to make routing data accessible to defined users or restrict access rights for defined areas or only to parts of the graph to a defined user group? The paper will present case studies and data from literature, where seamless and especially indoor navigation solutions are presented (hospitals, industrial complexes, building sites), but the problem of restricted access rights was only touched from a real world, but not a technical perspective. The analysis of case studies will show, that the objective of navigation and the different target groups for navigation solutions will demand well defined access rights and require solutions, how to make only parts of a graph to a user or application available to solve a navigational task. The paper will therefore introduce the concept of private graphs, which is defined as a graph for navigational purposes covering the street, road or floor network of an area behind a public street and suggest different approaches how to make graph data for navigational purposes available considering access rights and data protection, privacy and security issues as well.

  10. Flat-detector CT-based electromagnetic navigation

    International Nuclear Information System (INIS)

    Flat-detector CT coupled to an angiography device provides an imaging technique for interventions which can be used for electromagnetically navigated percutaneous punctures. This report explains the functionality of an electromagnetic navigation system and describes the course of an electromagnetically navigated puncture and the capabilities of such a system in the clinical routine. (orig.)

  11. A New Navigation Strategy in Hypermedia Integral Ware Authoring System

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    After analyzing the general navigation mechanisms and discussing the knowledge point card linking model which is the base of the navigation mechanism used in the Hypermedia Integral ware Authoring System(HIAS), the paper presents a new navigation strategy in HIAS. And the application trend of HIAS is discussed at last.

  12. 47 CFR 22.365 - Antenna structures; air navigation safety.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 2 2010-10-01 2010-10-01 false Antenna structures; air navigation safety. 22... Antenna structures; air navigation safety. Licensees that own their antenna structures must not allow these antenna structures to become a hazard to air navigation. In general, antenna structure owners...

  13. Time and Motion Study of a Community Patient Navigator

    Directory of Open Access Journals (Sweden)

    Sara S. Phillips

    2014-04-01

    Full Text Available Research on patient navigation has focused on validating the utility of navigators by defining their roles and analyzing their effects on patient outcomes, patient satisfaction, and cost effectiveness. Patient navigators are increasingly used outside the research context, and their roles without research responsibilities may look very different. This pilot study captured the activities of a community patient navigator for uninsured women with a positive screening test for breast cancer, using a time and motion approach over a period of three days. We followed the actions of this navigator minute by minute to assess the relative ratios of actions performed and to identify areas for time efficiency improvement to increase direct time with patients. This novel approach depicts the duties of a community patient navigator no longer fettered by navigation logs, research team meetings, surveys, and the consent process. We found that the community patient navigator was able to spend more time with patients in the clinical context relative to performing paperwork or logging communication with patients as a result of her lack of research responsibilities. By illuminating how community patient navigation functions as separate from the research setting, our results will inform future hiring and training of community patient navigators, system design and operations for improving the efficiency and efficacy of navigators, and our understanding of what community patient navigators do in the absence of research responsibilities.

  14. Fault-tolerant Sensor Fusion for Marine Navigation

    DEFF Research Database (Denmark)

    Blanke, Mogens

    2006-01-01

    Reliability of navigation data are critical for steering and manoeuvring control, and in particular so at high speed or in critical phases of a mission. Should faults occur, faulty instruments need be autonomously isolated and faulty information discarded. This paper designs a navigation solution...... events where the fault-tolerant sensor fusion provided uninterrupted navigation data despite temporal instrument defects...

  15. Robot navigation system using intrinsic evolvable hardware

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Recently there has been great interest in the idea that evolvable system based on the principle of ar tifcial intelligence can be used to continuously and autonomously adapt the behaviour of physically embedded systems such as autonomous mobile robots and intelligent home devices. Meanwhile, we have seen the introduc tion of evolvable hardware(EHW): new integrated electronic circuits that are able to continuously evolve to a dapt the chages in the environment implemented by evolutionary algorithms such as genetic algorithm(GA)and reinforcement learning. This paper concentrates on developing a robotic navigation system whose basic behav iours are obstacle avoidance and light source navigation. The results demonstrate that the intrinsic evolvable hardware system is able to create the stable robotiiuc behaviours as required in the real world instead of the tra ditional hardware systems.

  16. A wayfinding aid to increase navigator independence

    Directory of Open Access Journals (Sweden)

    Wilfred Waters

    2011-12-01

    Full Text Available Wayfinding aids are of great benefit because users do not have to rely on their learned geographic knowledge or orientation skills alone for successful navigation. Additionally, cognitive resources usually captured by this activity can be spent elsewhere. A challenge, however, remains for wayfinding aid developers. Due to the automation of wayfinding aids, navigator independence may be decreasing via the use of these aids. In order to address this, wayfinding aids might be improved additionally to perform a training role. Since the most versatile wayfinders appear to deploy a dual strategy for geographic orientation, it is proposed that wayfinding aids be improved to foster such an approach. This paper presents the results of an experimental study testing a portion of the suggested enhancement.

  17. Autonomous rough terrain navigation - Lessons learned

    Science.gov (United States)

    Miller, David P.

    1991-01-01

    Because of light-time delays, a planetary rover located on Mars or beyond will probably need to be able to navigate autonomously, in order to do significant exploration. Recent work at JPL has explored several different autonomous navigation strategies. This work includes highly deliberative methods that require large amounts of computation and internal storage but yield very planful behavior to more reactive systems that require less resources but whose behavior is more difficult to model. This paper briefly presents these methods, the results from experiments both in simulation and in the field, and some conclusions on the value of different approaches, and their possible impact on the structure of the robot and the mission architecture.

  18. Navigational mechanisms of migrating monarch butterflies.

    Science.gov (United States)

    Reppert, Steven M; Gegear, Robert J; Merlin, Christine

    2010-09-01

    Recent studies of the iconic fall migration of monarch butterflies have illuminated the mechanisms behind their southward navigation while using a time-compensated sun compass. Skylight cues, such as the sun itself and polarized light, are processed through both eyes and are probably integrated in the brain's central complex, the presumed site of the sun compass. Time compensation is provided by circadian clocks that have a distinctive molecular mechanism and that reside in the antennae. Monarchs might also use a magnetic compass because they possess two cryptochromes that have the molecular capability for light-dependent magnetoreception. Multiple genomic approaches are now being used with the aim of identifying navigation genes. Monarch butterflies are thus emerging as an excellent model organism in which to study the molecular and neural basis of long-distance migration. PMID:20627420

  19. Development of autonomous grasping and navigating robot

    Science.gov (United States)

    Kudoh, Hiroyuki; Fujimoto, Keisuke; Nakayama, Yasuichi

    2015-01-01

    The ability to find and grasp target items in an unknown environment is important for working robots. We developed an autonomous navigating and grasping robot. The operations are locating a requested item, moving to where the item is placed, finding the item on a shelf or table, and picking the item up from the shelf or the table. To achieve these operations, we designed the robot with three functions: an autonomous navigating function that generates a map and a route in an unknown environment, an item position recognizing function, and a grasping function. We tested this robot in an unknown environment. It achieved a series of operations: moving to a destination, recognizing the positions of items on a shelf, picking up an item, placing it on a cart with its hand, and returning to the starting location. The results of this experiment show the applicability of reducing the workforce with robots.

  20. An approximate model for pulsar navigation simulation

    Science.gov (United States)

    Jovanovic, Ilija; Enright, John

    2016-02-01

    This paper presents an approximate model for the simulation of pulsar aided navigation systems. High fidelity simulations of these systems are computationally intensive and impractical for simulating periods of a day or more. Simulation of yearlong missions is done by abstracting navigation errors as periodic Gaussian noise injections. This paper presents an intermediary approximate model to simulate position errors for periods of several weeks, useful for building more accurate Gaussian error models. This is done by abstracting photon detection and binning, replacing it with a simple deterministic process. The approximate model enables faster computation of error injection models, allowing the error model to be inexpensively updated throughout a simulation. Testing of the approximate model revealed an optimistic performance prediction for non-millisecond pulsars with more accurate predictions for pulsars in the millisecond spectrum. This performance gap was attributed to noise which is not present in the approximate model but can be predicted and added to improve accuracy.