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Sample records for class iii dentofacial

  1. Postura de cabeça nas deformidades dentofaciais classe II e classe III Head posture in the presence of class II and class III dentofacial deformities

    Directory of Open Access Journals (Sweden)

    Marcela Ralin de Carvalho Deda

    2012-04-01

    Full Text Available OBJETIVO: este estudo investiga se existe diferença entre grupos com diferentes deformidades dentofaciais (padrão classe II e classe III e o grupo sem a deformidade em relação à postura de cabeça. MÉTODO: participaram deste estudo, voluntariamente, 25 pacientes (entre 16 e 40 anos. Dez pacientes com diagnóstico de deformidade dentofacial classe II e 15 pacientes com o diagnóstico de classe III esquelética e 15 voluntários sadios, com equivalência em sexo e idade ao grupo de deformidade, formando o grupo controle. Primeiramente foi realizada a inspeção da postura de cabeça. Logo em seguida foi realizada a avaliação postural de cabeça por meio da fotografia postural (fotogrametria. RESULTADOS: não houve diferença significante (p>0,05 entre os grupos em relação à avaliação postural utilizando-se a fotogrametria. Já em relação à avaliação postural pela inspeção clínica, observou-se uma postura anterior de cabeça nos indivíduos com a deformidade dentofacial padrão classe II, comparados ao padrão classe III (p = 0,001 e ao grupo controle (p = 0,001. Foi visto também que o grupo deformidade classe II apresentou um percentual inferior de indivíduos com posição neutra de cabeça comparado ao grupo deformidade classe III (p = 0,008 e ao grupo controle (p = 0,001. CONCLUSÃO: indivíduos com deformidade dentofacial classe II podem apresentar uma anteriorização de cabeça. Não há influência da deformidade no aumento ou na redução do ângulo cabeça-pescoço, analisado por meio da fotogrametria.PURPOSE: this study investigates whether there is a difference in head posture between groups with different dentofacial deformities (class II and class III and a group with no deformity. METHOD: 25 volunteers aged from 16 to 40 year old took part in the study. Ten patients had a diagnosis of class II dentofacial deformity, 15 had a diagnosis of class III skeletal deformity, and 15 healthy volunteers matched for sex and

  2. Cone-beam computed tomography based evaluation of rotational patterns of dentofacial structures in skeletal Class III deformity with mandibular asymmetry

    OpenAIRE

    Ryu, Hyeong-Seok; An, Ki-Yong; Kang, Kyung-Hwa

    2015-01-01

    Objective The purpose of this study was to assess rotational patterns of dentofacial structures according to different vertical skeletal patterns by cone-beam computed tomography (CBCT) and analyze their influence on menton deviation in skeletal Class III deformity with mandibular asymmetry. Methods The control group consisted of 30 young adults (15 men, 15 women) without any severe skeletal deformity. The asymmetry group included 55 adults (28 men, 27 women) with skeletal Class III deformity...

  3. Dentofacial characteristics of patients with Angle Class I and Class II malocclusions

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    Rogério Lacerda dos Santos

    2012-04-01

    Full Text Available OBJECTIVE: The present study assessed some cephalometric measurements of the soft tissue profile in order to observe the behavior of facial convexity in patients with Class I, Class II division 1, and Class II division 2 malocclusions. METHODS: One hundred and thirty pre-treatment teleradiographs of Caucasian patients aged 10-16 years (mean age of 12.6 years were selected for study and divided into 3 groups. The cephalometric measurements used in the present study were the following: H.SN, Cx, NLA, MLA, UL-SUL-S, LL-S, IMPA, and 1-SN. Analysis of variance and Tukey's test were applied for measurements H.SN, Cx, IMPA, 1-SN, MLA, and NLA, whereas Kruskal-Wallis and Dunn's tests were applied for UL-S and LL-S. RESULTS: The results showed statistically significant differences for the measurements H.SN, Cx, UL-S, and IMPA between Groups I, II-1 and II-2 (p < 0.05. Measurements LL-S and MLA showed statistically significant difference between Groups I and II-1 only (p < 0.05. On the other hand, no statistically significant differences were found for measurement NLA among the 3 groups (p < 0.05. CONCLUSION: Regarding facial characteristics expressed by measurements H.SN, Cx, and UL-S, one could conclude that Class II division 1 and Class II division 2 malocclusions, both differed from Class I malocclusion. In addition, Class II division 1 malocclusion was found to have facial characteristics expressed by MLA, which differentiate it from the Class II division 2 and Class 1 malocclusions. Class I, Class II division 1 and Class II division 2 malocclusions showed no difference in facial characteristics expressed by the measurement NLA, and measurement LL-S was directly related to eversion of the lower lip.

  4. Dentofacial characteristics of patients with Angle Class I and Class II malocclusions

    OpenAIRE

    Rogério Lacerda dos Santos; Antônio Carlos de Oliveira Ruellas

    2012-01-01

    OBJECTIVE: The present study assessed some cephalometric measurements of the soft tissue profile in order to observe the behavior of facial convexity in patients with Class I, Class II division 1, and Class II division 2 malocclusions. METHODS: One hundred and thirty pre-treatment teleradiographs of Caucasian patients aged 10-16 years (mean age of 12.6 years) were selected for study and divided into 3 groups. The cephalometric measurements used in the present study were the following: H.SN, C...

  5. Class III treatment using facial mask: Stability after 10 years

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    Adilson Luiz Ramos

    2014-10-01

    Full Text Available Early Class III malocclusion treatment may not have long-term stability due to mandibular growth. Although some features of this malocclusion point to a better prognosis, it is practically impossible for the orthodontist to foresee cases that require new intervention. Many patients need retreatment, whether compensatory or orthodontic-surgical. The present study reports the case of a Class III patient treated at the end of the mixed dentition with the use of a face mask followed by conventional fixed appliances. The case remains stable 10 years after treatment completion. It was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO as a requirement for the title of certified by the BBO.

  6. Pseudo Class III malocclusion.

    Science.gov (United States)

    Al-Hummayani, Fadia M

    2016-04-01

    The treatment of deep anterior crossbite is technically challenging due to the difficulty of placing traditional brackets with fixed appliances. This case report represents a none traditional treatment modality to treat deep anterior crossbite in an adult pseudo class III malocclusion complicated by severely retruded, supraerupted upper and lower incisors. Treatment was carried out in 2 phases. Phase I treatment was performed by removable appliance "modified Hawley appliance with inverted labial bow," some modifications were carried out to it to suit the presented case. Positive overbite and overjet was accomplished in one month, in this phase with minimal forces exerted on the lower incisors. Whereas, phase II treatment was performed with fixed appliances (braces) to align teeth and have proper over bite and overjet and to close posterior open bite, this phase was accomplished within 11 month. PMID:27052290

  7. Pseudo Class III malocclusion

    Science.gov (United States)

    Al-Hummayani, Fadia M.

    2016-01-01

    The treatment of deep anterior crossbite is technically challenging due to the difficulty of placing traditional brackets with fixed appliances. This case report represents a none traditional treatment modality to treat deep anterior crossbite in an adult pseudo class III malocclusion complicated by severely retruded, supraerupted upper and lower incisors. Treatment was carried out in 2 phases. Phase I treatment was performed by removable appliance “modified Hawley appliance with inverted labial bow,” some modifications were carried out to it to suit the presented case. Positive overbite and overjet was accomplished in one month, in this phase with minimal forces exerted on the lower incisors. Whereas, phase II treatment was performed with fixed appliances (braces) to align teeth and have proper over bite and overjet and to close posterior open bite, this phase was accomplished within 11 month. PMID:27052290

  8. Three-dimensional comparison of the upper airway in various types of dentofacial deformities

    OpenAIRE

    Chong, Mei-man.; 臧薇敏.

    2012-01-01

    Objectives 1. To define the normative airway of Chinese population using three-dimensional imaging and computer analysis 2. To evaluate the upper airway differences in patients with normal facial profile and those with skeletal class III deformity 3. To evaluate the differences in upper airway models among patients with different dentofacial deformities and describe the role of computational fluid dynamics (CFD) in the human upper airway Materials and Methods Part I : Th...

  9. Orthodontic retreatment of a Class III patient with significant midline asymmetry and bilateral posterior crossbite.

    Science.gov (United States)

    Brunetto, Ademir R

    2015-01-01

    Posterior crossbite might cause serious long-term functional problems if not early treated. Nevertheless, in older patients, treatment might include palatal expansion in order to correct such malocclusion. In view of the above, this article aims at reporting late correction of bilateral posterior crossbite associated with Angle Class III malocclusion, right subdivision, with consequent midline shift (good skeletal pattern). The case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO), with DI equal to or greater than 10, as a requirement for the title of certified by the BBO. PMID:25741833

  10. Orthodontic retreatment of a Class III patient with significant midline asymmetry and bilateral posterior crossbite

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    Ademir R. Brunetto

    2015-02-01

    Full Text Available Posterior crossbite might cause serious long-term functional problems if not early treated. Nevertheless, in older patients, treatment might include palatal expansion in order to correct such malocclusion. In view of the above, this article aims at reporting late correction of bilateral posterior crossbite associated with Angle Class III malocclusion, right subdivision, with consequent midline shift (good skeletal pattern. The case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO, with DI equal to or greater than 10, as a requirement for the title of certified by the BBO.

  11. Orthodontic retreatment using anchorage with miniplate to camouflage a Class III skeletal pattern.

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    Farret, Marcel Marchiori

    2016-06-01

    This manuscript describes the treatment of a 27-year-old patient who was previously treated with two maxillary first premolar extractions. The patient had skeletal Class III malocclusion, Class III canine relationship, anterior crossbite, and a concave profile. As the patient refused orthognathic surgery, a miniplate was used on the right side of the lower arch as an anchorage unit after the extraction of mandibular first premolars, aiding the retraction of anterior teeth. At the end of treatment, anterior crossbite was corrected, in which first molars and canines were in a Class I relationship, and an excellent intercuspation was reached. Furthermore, patient's profile remarkably improved as a result of mandibular incisor retraction. A 30-month follow-up showed good stability of the results obtained. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as one of the requirements to become diplomate by the BBO. PMID:27409659

  12. 25 CFR 502.4 - Class III gaming.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Class III gaming. 502.4 Section 502.4 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR GENERAL PROVISIONS DEFINITIONS OF THIS CHAPTER § 502.4 Class III gaming. Class III gaming means all forms of gaming that are not class I gaming or...

  13. 25 CFR 522.12 - Revocation of class III gaming.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Revocation of class III gaming. 522.12 Section 522.12 Indians NATIONAL INDIAN GAMING COMMISSION, DEPARTMENT OF THE INTERIOR APPROVAL OF CLASS II AND CLASS III ORDINANCES AND RESOLUTIONS SUBMISSION OF GAMING ORDINANCE OR RESOLUTION § 522.12 Revocation of class...

  14. Class III malocclusion with severe anteroposterior discrepancy

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    Susana Maria Deon Rizzatto

    2012-10-01

    Full Text Available This study aims at reporting the clinical case of a patient with Class III skeletal malocclusion with severe maxillary deficiency, producing a reduced midface associated with severe mandibular prognathism. The pre-surgical orthodontic preparation was composed mainly by dentoalveolar expansion and repositioning of the incisors in the lower arch. Then, a combined maxillary and mandibular orthognathic surgery was performed. The treatment objectives were achieved, with significant improvement in facial esthetics and occlusion, followed by post-treatment stability. This case was presented to the Brazilian Board of Orthodontics and Facial Orthopedics (BBO, as part of the requirements for obtaining the title of Diplomate by BBO.O objetivo deste artigo é relatar o caso clínico de um paciente portador de má oclusão de Classe III esquelética com acentuada deficiência maxilar, causando redução do terço médio da face, associada a severo prognatismo mandibular. O preparo ortodôntico pré-cirúrgico foi composto, principalmente, pela expansão dentoalveolar da maxila e o reposicionamento dos incisivos na arcada inferior. Depois, foi realizada a cirurgia ortognática combinada maxilomandibular. Os objetivos do tratamento foram atingidos, com significativa melhora da oclusão e da estética facial, seguida de estabilidade pós-tratamento. Esse caso foi apresentado à Diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO, como parte dos requisitos para obtenção do título de Diplomado pelo BBO.

  15. ORTHOGNATIC SURGICAL TREATMENT OF SKELETAL CLASS III MALOCLUSION: CASE REPORT

    OpenAIRE

    GÜNGÖR, AHMET YALÇIN; Turkkahraman, Hakan; Baykul, Timucin; Aydın, Asım

    2012-01-01

    In this case report a case is presented with skeletal class III malocclusion which were treated with proper planned orthognatic surgery and orthodontic treatment. Our patient was a girl with 16 years, 3 months of chronologic and Ru period of skeletal age. A concave soft tissue profile and Class III molar relation was detected in extraoral and intraoral examination. Cephalometric evaluation revealed a significant Class III skeletal discrepancy (ANBº= -6). Presurgical orthodontics involved deco...

  16. Archform Comparisons between Skeletal Class II and III Malocclusions

    OpenAIRE

    Zou, Wei; Wu, Jiaqi; Jiang, JiuHui; Xu, Tianmin; Li, CuiYing

    2014-01-01

    The purpose of this cross-sectional research was to explore the relationship of the mandibular dental and basal bone archforms between severe Skeletal Class II (SC2) and Skeletal Class III (SC3) malocclusions. We also compared intercanine and intermolar widths in these two malocclusion types. Thirty-three virtual pretreatment mandibular models (Skeletal Class III group) and Thirty-five Skeletal Class II group pretreatment models were created with a laser scanning system. FA (the midpoint of t...

  17. Class III Malocclusion Surgical-Orthodontic Treatment

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    Furquim, Bruna Alves; de Freitas, Karina Maria Salvatore; Janson, Guilherme; Simoneti, Luis Fernando; de Freitas, Marcos Roberto; de Freitas, Daniel Salvatore

    2014-01-01

    The aim of the present case report is to describe the orthodontic-surgical treatment of a 17-year-and-9-month-old female patient with a Class III malocclusion, poor facial esthetics, and mandibular and chin protrusion. She had significant anteroposterior and transverse discrepancies, a concave profile, and strained lip closure. Intraorally, she had a negative overjet of 5 mm and an overbite of 5 mm. The treatment objectives were to correct the malocclusion, and facial esthetic and also return the correct function. The surgical procedures included a Le Fort I osteotomy for expansion, advancement, impaction, and rotation of the maxilla to correct the occlusal plane inclination. There was 2 mm of impaction of the anterior portion of the maxilla and 5 mm of extrusion in the posterior region. A bilateral sagittal split osteotomy was performed in order to allow counterclockwise rotation of the mandible and anterior projection of the chin, accompanying the maxillary occlusal plane. Rigid internal fixation was used without any intermaxillary fixation. It was concluded that these procedures were very effective in producing a pleasing facial esthetic result, showing stability 7 years posttreatment. PMID:25431691

  18. Orthodontic treatment alternative to a class III subdivision malocclusion

    OpenAIRE

    Guilherme Janson; José Eduardo Prado de Souza; Sérgio Estelita Cavalcante Barros; Pedro Andrade Junior; Alexandre Yudi Nakamura

    2009-01-01

    Class III malocclusions are considered one of the most complex and difficult orthodontic problems to diagnose and treat. Skeletal and/or dental asymmetries in patients presenting with Class III malocclusions can worsen the prognosis. Recognizing the dentoalveolar and skeletal characteristics of subdivision malocclusions and their treatment possibilities is essential for a favorable nonsurgical correction. Therefore, this article presents a nonsurgical asymmetric extraction approach to Class I...

  19. Presence of Third Molar Germs in Orthodontic Patients with Class II/2 and Class III Malocclusions

    OpenAIRE

    Maričić, Barbara Mady; Legović, Mario; Šlaj, Martina; Lapter Varga, Marina; Žuvić Butorac, Marta; Kapović, Miljenko

    2009-01-01

    The aim of this study was to determine the presence of third molar germs in patients with Class II/2 and Class III malocclusions. The study comprised 146 examinees from Zagreb and Istria. Examinees with Class II/2 malocclusions amounted to 77 and those with Class III 69. With regard to development of dentition the examinees were divided into two groups: Group I subjects with early mixed dentition (23 subjects with Class II/2 and 21 subjects with Class III), and Group II subjects with late mix...

  20. Orthodontics-surgical combination therapy for Class III skeletal malocclusion

    OpenAIRE

    Ravi, M. S.; Nillan K Shetty; Prasad, Rajendra B.

    2012-01-01

    The correction of skeletal Class III malocclusion with severe mandibular prognathism in an adult individual requires surgical and Othodontic combination therapy. The inter disciplinary approach is the treatment of choice in most of the skeletal malocclusions. A case report of an adult individual with Class III malocclusion, having mandibular excess in sagittal and vertical plane and treated with orthodontics,, bilateral sagittal split osteotomy and Le - Forte I osteotomy for the correction of...

  1. A benefit-risk assessment of class III antiarrhythmic agents

    DEFF Research Database (Denmark)

    Elming, Hanne; Brendorp, Bente; Pehrson, Steen;

    2004-01-01

    relief. Since many patients experience a decrease in physical performance as well as a diminished quality of life during arrhythmia there is still a need for antiarrhythmic drug therapy. The development of new antiarrhythmic agents has changed the focus from class I to class III agents since it became...... evident that with class I drug therapy the prevalence of mortality is considerably higher. This review focuses on the benefits and risks of known and newer class III antiarrhythmic agents. The benefits discussed include the ability to maintain sinus rhythm in persistent atrial fibrillation patients, and...... reducing the need for implantable cardioverter defibrillator shock/antitachycardia therapy, since no class III antiarrhythmic agents have proven survival benefit. The risks discussed mainly focus on pro-arrhythmia as torsade de pointes ventricular tachycardia....

  2. Dentofacial injuries in contact sports in Yaounde, Cameroon

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    M A Agbor

    2012-01-01

    Full Text Available Background: Dentofacial injuries constitute serious problems among competitive and recreational athletes, worldwide. Objective: To determine the prevalence of dentofacial injuries and related factors among individuals participating in contact sports in Yaoundé, Cameroon. Materials and Methods: This cross-sectional study among individuals participating in karate, judo, basketball, handball, football and wrestling in Yaoundé, Cameroon was conducted between January and April, 2012. Results: Of the 240 athletes interviewed, 115 and 89 of them reported bodily and dentofacial injuries giving 47.9% and 37.1% prevalence, respectively. The bodily injuries were limbs-(60.0%, chest-(23.5%, abdomen-(11.3% and neck- (5.2%. Mouth and face accounted for 52.8% and 37.1% of the dentofacial injuries, respectively. Other dentofacial injuries were teeth-(6.7% and mandible-(3.4%. Older athletes and years of participation were more likely to experience dentofacial injuries. Karate was the most common cause of dentofacial injuries followed by wrestling. The prevalence of the dentofacial injuries was similar among both genders and was equally prevalent during training and competition. The personal protective equipment use reduced the likelihood of dentofacial injuries among the athletes. Conclusion: The prevalence of dentofacial injuries were high while the personal protective equipment use was low among the individuals participating in contact sports in Yaoundé, Cameroon.

  3. Dentofacial Asymmetries: Challenging Diagnosis and Treatment Planning.

    Science.gov (United States)

    Agrawal, Manish; Agrawal, Jiwan Asha; Nanjannawar, Lalita; Fulari, Sangamesh; Kagi, Vishwal

    2015-07-01

    Dentofacial asymmetry is quite common and when sufficiently severe can require surgical orthodontic intervention. Asymmetries can be classified according to the structures involved into skeletal, dental and functional. In diagnosing asymmetries, a thorough clinical examination and radiographic survey are essential to determine the extent of soft tissue, skeletal, dental and functional involvement. Dental asymmetries, as well as a variety of functional deviations, can be managed orthodontically, whereas significant structural facial asymmetries require a comprehensive orthodontic and orthognathic management. With less severe dental, skeletal and soft tissue deviations the advisability of treatment should be carefully considered. The following article also contains a case report highlighting the importance of proper diagnosis in treatment plan for management of dentofacial asymmetry. PMID:26229387

  4. Dentofacial Asymmetries: Challenging Diagnosis and Treatment Planning

    OpenAIRE

    Agrawal, Manish; Agrawal, Jiwan Asha; Nanjannawar, Lalita; Fulari, Sangamesh; Kagi, Vishwal

    2015-01-01

    Dentofacial asymmetry is quite common and when sufficiently severe can require surgical orthodontic intervention. Asymmetries can be classified according to the structures involved into skeletal, dental and functional. In diagnosing asymmetries, a thorough clinical examination and radiographic survey are essential to determine the extent of soft tissue, skeletal, dental and functional involvement. Dental asymmetries, as well as a variety of functional deviations, can be managed orthodonticall...

  5. Conservative treatment of Angle Class III malocclusion with anterior crossbite

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    João Hélder Ferreira de Aguiar

    2015-08-01

    Full Text Available Angle Class III malocclusion is characterized by anteroposterior dental discrepancy which might be associated or not with skeletal changes. Class III molar relationship is associated with vertical or lingually tipped mandibular incisors and a usually concave profile. These characteristics seriously affect facial esthetics and most frequently are the reason why patients seek orthodontic treatment. This case was presented to the committee of the Brazilian Board of Orthodontics and Facial Orthopedics (BBO as part of the requisites to become a BBO Diplomate.

  6. 25 CFR 291.5 - Where must the proposal requesting Class III gaming procedures be filed?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Where must the proposal requesting Class III gaming... ECONOMIC ENTERPRISES CLASS III GAMING PROCEDURES § 291.5 Where must the proposal requesting Class III gaming procedures be filed? Any proposal requesting Class III gaming procedures must be filed with...

  7. Reassessing Pre-market Regulation of Class III Medical Devices

    OpenAIRE

    Zollinger, Geri

    2003-01-01

    Regulation of medical devices has evolved over the past twenty-five years. Initially, Congress created a regime where the safety and efficacy of all medical devices would be reviewed to varying degrees, depending on the risk posed by the device. Class III devices, the most dangerous class of devices, were to each have a safety and efficacy review. To permit new market entrants on similar grounds as those marketing devices prior to the 1976 Amendments, Congress also created a premarket notific...

  8. Prevalence of dentofacial abnormalities in children and adolescents with β-thalassaemia major

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    Arun Elangovan

    2013-01-01

    Full Text Available Background: β-thalassaemia major is a hereditary hemolytic anemia and the patients often experience growth retardation, protrusive maxilla, and depressed nasal bride leading to various degrees of malocclusion. Aim: The purpose of this investigation is to find the prevalence of dentofacial abnormalities in β-thalassaemia major patients. Subjects and Methods: Seventy-two patients between 6 and 18 years of age diagnosed with β-thalassaemia major were examined for extraoral abnormalities, malocclusion, oral hygiene, and dental caries. Data obtained were tabulated and statistically analyzed using Chi-square and paired t-test. Results: Thirty-nine (54.2% were males and 33 (45.8% were females. Prominent extraoral abnormalities were found in 41 (56.9% of the individuals. Study population predominantly had class I occlusion (59.7% followed by class II occlusion (23.6% and no class III occlusion. Mean oral hygiene index-simplified score was 2.43 ± 1.24, mean decayed missing filled teeth (DMFT score was 7.10 ± 3.92, and deft was 5.68 ± 3.12. Conclusion: Despite starting regular blood transfusion at an early age, β-thalassaemia major patients showed marked facial abnormalities. When compared with individuals with no systemic disease, oral hygiene status was similar, but the caries experience was higher in β-thalassaemia major patients. Therefore, emphasis to educate these patients in the prevention and control of dental caries and maintenance of good oral hygiene should be considered.

  9. Orthodontics-surgical combination therapy for Class III skeletal malocclusion

    Directory of Open Access Journals (Sweden)

    M S Ravi

    2012-01-01

    Full Text Available The correction of skeletal Class III malocclusion with severe mandibular prognathism in an adult individual requires surgical and Othodontic combination therapy. The inter disciplinary approach is the treatment of choice in most of the skeletal malocclusions. A case report of an adult individual with Class III malocclusion, having mandibular excess in sagittal and vertical plane and treated with orthodontics,, bilateral sagittal split osteotomy and Le - Forte I osteotomy for the correction of skeletal, dental and soft tissue discrepancies is herewith presented. The surgical-orthodontic combination therapy has resulted in near-normal skeletal, dental and soft tissue relationship, with marked improvement in the facial esthetics in turn, has helped the patient to improve the self-confidence level.

  10. Skeletal components of class III malocclusions and compensation mechanisms.

    Science.gov (United States)

    Spalj, S; Mestrovic, S; Lapter Varga, M; Slaj, M

    2008-08-01

    The aim of this retrospective study was to assess the skeletal characteristics of sagittal maxillary and mandibular discrepancies resulting in class III malocclusions and compensation mechanisms in one Caucasian European population (Croatian). The study sample included 107 patients (63 females and 44 males), aged between 11 and 18 years of age (mean age 14.6 +/- 2.2), with a class III malocclusion. Forty-three angular and linear measurements were assessed from the pre-treatment lateral cephalographs of each subject. anova, Tukey post hoc and t-test were used for statistical analysis. The most common differential skeletal type was mandibular prognathism with a normal maxilla (43%), followed by maxillary retrognathism with a normal mandibular position (19.6%), while the combination of maxillary retrognathism and mandibular prognathism was found to be rare (Habsburg jaw'. PMID:18699972

  11. Orthodontic-surgical treatment of the skeletal class III malocclusion: A case report

    OpenAIRE

    Stojanović Ljiljana S.; Mileusnić Ivan; Mileusnić Budimir; Čutović Tatjana

    2013-01-01

    Background. Class III malocclusions are considered to be ones of the most difficult problems to treat. Their causes are multifactorial and include genetic and/or environmental factors. Class III malocclusions are generally classified into 2 categories: skeletal and dental. The diagnosis is important due to the different treatment approaches. Generally a dental class III can be treated with orthodontics alone, while a true skeletal class III requires a combi...

  12. 25 CFR 291.4 - What must a proposal requesting Class III gaming procedures contain?

    Science.gov (United States)

    2010-04-01

    ... integrity of gaming operations as set forth in 25 CFR Part 542; (5) Provisions for records retention... 25 Indians 1 2010-04-01 2010-04-01 false What must a proposal requesting Class III gaming... ENTERPRISES CLASS III GAMING PROCEDURES § 291.4 What must a proposal requesting Class III gaming...

  13. Compensatory canine angulation in angle Class II and III patients

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    Mauro Carlos Agner Busato

    2009-09-01

    Full Text Available The aim of this study was to evaluate the occurence of compensation in mesiodistal axial inclinations of canines in skeletal malocclusions patients. The sample consisted of 25 Angle Class II, division 1 malocclusion (group 1 and 19 Angle Class III malocclusion patients (group 2. After measurement of dental angulations through a method that associates plaster model photography and AutoCad software, comparisons between the groups were performed by T-test for independent samples. Results showed that there was no statistically significant difference (p < 0.05 between groups, when maxillary canine angulations were compared. Regarding the mandibular canines, there was a statistically significant difference in dental angulation, expressed by 3.2° for group 1 and 0.15° for group 2. An upright position tendency for mandibular canines was observed in the Angle Class III sample. This configures a pattern of compensatory coronary positioning, since the angulation of these teeth makes them occupy less space in the dental arch and consequently mandibular incisors can be in a more retracted position in the sagittal plane.

  14. Genetics of the dentofacial variation in human malocclusion

    OpenAIRE

    Moreno Uribe, L. M.; Miller, S. F.

    2015-01-01

    Malocclusions affect individuals worldwide, resulting in compromised function and esthetics. Understanding the etiological factors contributing to the variation in dentofacial morphology associated with malocclusions is the key to develop novel treatment approaches. Advances in dentofacial phenotyping, which is the comprehensive characterization of hard and soft tissue variation in the craniofacial complex, together with the acquisition of large-scale genomic data have started to unravel gene...

  15. Diverse functions and reactions of class III peroxidases.

    Science.gov (United States)

    Shigeto, Jun; Tsutsumi, Yuji

    2016-03-01

    Higher plants contain plant-specific peroxidases (class III peroxidase; Prxs) that exist as large multigene families. Reverse genetic studies to characterize the function of each Prx have revealed that Prxs are involved in lignification, cell elongation, stress defense and seed germination. However, the underlying mechanisms associated with plant phenotypes following genetic engineering of Prx genes are not fully understood. This is because Prxs can function as catalytic enzymes that oxidize phenolic compounds while consuming hydrogen peroxide and/or as generators of reactive oxygen species. Moreover, biochemical efforts to characterize Prxs responsible for lignin polymerization have revealed specialized activities of Prxs. In conclusion, not only spatiotemporal regulation of gene expression and protein distribution, but also differentiated oxidation properties of each Prx define the function of this class of peroxidases. PMID:26542837

  16. Vertical control in the Class III compensatory treatment

    Directory of Open Access Journals (Sweden)

    Márcio Costa Sobral

    2013-04-01

    Full Text Available INTRODUCTION: Compensatory orthodontic treatment, or simply orthodontic camouflage, consists in an important alternative to orthognathic surgery in the resolution of skeletal discrepancies in adult patients. It is important to point that, to be successfully performed, diagnosis must be detailed, to evaluate, specifically, dental and facial features, as well as the limitations imposed by the magnitude of the discrepancy. The main complaint, patient's treatment expectation, periodontal limits, facial pattern and vertical control are some of the items to be explored in the determination of the viability of a compensatory treatment. Hyperdivergent patients who carry a Class III skeletal discrepancy, associated with a vertical facial pattern, with the presence or tendency to anterior open bite, deserve special attention. In these cases, an efficient strategy of vertical control must be planned and executed. OBJECTIVE: The present article aims at illustrating the evolution of efficient alternatives of vertical control in hiperdivergent patients, from the use, in the recent past, of extra-oral appliances on the lower dental arch (J-hook, until nowadays, with the advent of skeletal anchorage. But for patients with a more balanced facial pattern, the conventional mechanics with Class III intermaxillary elastics, associated to an accentuated curve of Spee in the upper arch and a reverse Curve of Spee in the lower arch, and vertical elastics in the anterior region, continues to be an excellent alternative, if there is extreme collaboration in using the elastics.

  17. Evaluation of arch width among Class I normal occlusion, Class II Division 1, Class II Division 2, and Class III malocclusion in Indian population

    OpenAIRE

    Dolly Patel; Falguni Mehta; Nimesh Patel; Nishit Mehta; Ipist Trivedi; Apexa Mehta

    2015-01-01

    Objective: To test the hypothesis that there is no difference between Class I (CI) normal occlusion, Class II division 1 (CIId1) and CII division 2 (CIId2), and Class III (CIII) malocclusion with respect to arch widths, width of the maxillary and mandibular arches, gender dimorphism within groups, and gender comparisons. Materials and Methods: Samples of 40 CI subjects, 40 CIId1 subjects, 40 CIId2 subjects, and 34 CIII subjects were studied. All subjects were Indians with no history of or...

  18. Evaluation depth of the curve of Spee in class I, class II, and class III malocclusion: A cross sectional study

    Directory of Open Access Journals (Sweden)

    Sanjna Nayar

    2015-01-01

    Full Text Available Occlusal plane is an essential consideration when multiple long-span posterior restorations are designed. When restorations are added to an existing tooth arrangement characterized by rotated, tipped, or extruded teeth, excursive interferences may be incorporated, resulting in detrimental squeal. The curve of Spee, which exists in the ideal natural dentition, allows harmony to exist between the anterior tooth and condylar guidance. This curve exists in the sagittal plane and is the best viewed from a lateral aspect. It permits total posterior disclusion on mandibular protrusion, given proper anterior tooth guidance. It is unclear that whether the curve of Spee is a description of the occlusal surface of each arch separately or in maximal intercuspation. The purpose of this study was to examine the differences in the depth of curve of Spee between the class I, class II, class III and to investigate the relationship of depth of curve of Spee with over jet, over-bite.

  19. Morphometric analysis of treatment effects of bone-anchored maxillary protraction in growing Class III patients

    OpenAIRE

    Baccetti, T.; Clerck, H.J. de; Cevidanes, L. H.; Franchi, L

    2010-01-01

    The aim of the present morphometric investigation was to evaluate the effects of bone-anchored maxillary protraction (BAMP) in the treatment of growing patients with Class III malocclusion. The shape and size changes in the craniofacial configuration of a sample of 26 children with Class III malocclusions consecutively treated with the BAMP protocol were compared with a matched sample of 15 children with untreated Class III malocclusions. All subjects in the two groups were at a prepubertal s...

  20. Skeletal class III camouflage by mandibular incisor extraction: A case report

    OpenAIRE

    Janardhanan Kumaresan; Tamizharasi Senthil Kumar; Senthil Kumar

    2014-01-01

    Treatment planning in orthodontics plays a key role in determining the successful treatment of any kind of malocclusion. Skeletal class III malocclusions are generally difficult to treat because of the complex nature of the skeletal and dental manifestations they produce. Mild to moderate skeletal class III malocclusions sometimes have an acceptable facial profile where orthodontic camouflage is possible. In this case report, camouflage of a mild skeletal class III is done by the extraction o...

  1. The influence of dentofacial appearance on the social attractiveness of young adults.

    Science.gov (United States)

    Shaw, W C; Rees, G; Dawe, M; Charles, C R

    1985-01-01

    The purpose of the study was to determine whether the social attractiveness of a young adult would be influenced by his or her dentofacial appearance. Black and white photographs of an attractive male, an unattractive male, an attractive female, and an unattractive female were obtained and modified so that, for each face, five different photographic versions were available. In each version, the face was standardized except that a different dentofacial arrangement was demonstrated. These were normal incisors, prominent incisors, absence of upper left lateral incisor, severely crowded incisors, and unilateral cleft lip. Eight hundred young adults were shown one of the twenty photographs and asked to estimate the represented individual's social characteristics along a number of bipolar scales. Each photograph was viewed by a different group of forty young adults, equally divided as to sex. Their impressions of the depicted individuals' social attractiveness were recorded on visual analogue scales. The experimental procedure was such that the effect and interaction of different levels of facial attractiveness, different dentofacial arrangements, sex of the photographed individual, and sex of the judge could be analyzed. Faces displaying a normal incisor relationship gained the most favorable ratings for eight of the ten characteristics examined, and in four of these differences across the range of dental conditions were statistically significant. These were perceived friendliness, social class, popularity, and intelligence. The prominent incisor condition was rated highest for compliance and honesty, while the condition representing a unilateral cleft consistently attracted low ratings. Background facial attractiveness of either the male or female stimuli was often more assertive than the individual dental condition.(ABSTRACT TRUNCATED AT 250 WORDS) PMID:3855347

  2. Surgical treatment of dental and skeletal Class III malocclusion

    Directory of Open Access Journals (Sweden)

    Ione Helena Vieira Portella Brunharo

    2013-02-01

    Full Text Available Orthodontic preparation for surgical treatment of skeletal Class III malocclusion involves joint planning with an oral and maxillofacial surgeon to address the functional and esthetic needs of the patient. In order to allow surgical manipulation of the jaws in the preoperative phase, the need to achieve a negative overjet through incisor decompensation often leads the orthodontist to extract the upper first premolars. This report illustrates an orthodontic preparation case where due to specific factors inherent in the patient's psychological makeup retroclination of the upper incisors and proclination of the mandibular incisors was achieved without removing any teeth. This case was presented to the Brazilian Board of Orthodontics and Facial Orthopedics (BBO in partial fulfillment of the requirements for obtaining the BBO Diploma.O preparo ortodôntico para tratamento cirúrgico do padrão esquelético de Classe III envolve o planejamento em conjunto com o cirurgião bucomaxilofacial, com o objetivo de solucionar as necessidades funcionais e estéticas do paciente. A fim de permitir a manipulação cirúrgica das bases ósseas, a obtenção de overjet negativo por meio da descompensação dos incisivos, na fase pré-cirúrgica, leva, com frequência, o ortodontista a optar pela exodontia dos primeiros pré-molares superiores. O presente relato ilustra um caso de preparo ortodôntico no qual, devido a fatores específicos inerentes à questão psicológica da paciente, a retroinclinação dos incisivos superiores e vestibularização dos incisivos inferiores foi realizada sem a remoção de elementos dentários. Esse caso foi apresentado à diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO como parte dos requisitos para a obtenção do título de Diplomado pelo BBO.

  3. 76 FR 43701 - Renewal of Agency Information Collection for Class III Tribal State Gaming Compact Process...

    Science.gov (United States)

    2011-07-21

    ... Bureau of Indian Affairs Renewal of Agency Information Collection for Class III Tribal State Gaming... the collection of information for the Class III Tribal State Gaming Compact Process. The information... comments on the information collection to Paula L. Hart, Director, Office of Indian Gaming, 1849 C...

  4. 77 FR 48167 - Approved Tribal-State Class III Gaming Compact; Indian Gaming

    Science.gov (United States)

    2012-08-13

    ... Bureau of Indian Affairs Approved Tribal--State Class III Gaming Compact; Indian Gaming AGENCY: Bureau of Indian Affairs, Interior. ACTION: Notice of Approved Tribal--State Class III Gaming Compact. SUMMARY: This notice publishes an approval of the gaming compact between the Eastern Band of Cherokee...

  5. 78 FR 14352 - Notice of Approved Class III Tribal Gaming Ordinances

    Science.gov (United States)

    2013-03-05

    ... National Indian Gaming Commission Notice of Approved Class III Tribal Gaming Ordinances AGENCY: National Indian Gaming Commission. ACTION: Notice. SUMMARY: The purpose of this notice is to inform the public of the approved Class III tribal gaming ordinances. DATES: Effective Date: This notice is effective...

  6. The biowaiver extension for BCS class III drugs: the effect of dissolution rate on the bioequivalence of BCS class III immediate-release drugs predicted by computer simulation.

    Science.gov (United States)

    Tsume, Yasuhiro; Amidon, Gordon L

    2010-08-01

    The Biopharmaceutical Classification System (BCS) guidance issued by the FDA allows waivers for in vivo bioavailability and bioequivalence studies for immediate-release (IR) solid oral dosage forms only for BCS class I drugs. However, a number of drugs within BCS class III have been proposed to be eligible for biowaivers. The World Health Organization (WHO) has shortened the requisite dissolution time of BCS class III drugs on their Essential Medicine List (EML) from 30 to 15 min for extended biowaivers; however, the impact of the shorter dissolution time on AUC(0-inf) and C(max) is unknown. The objectives of this investigation were to assess the ability of gastrointestinal simulation software to predict the oral absorption of the BCS class I drugs propranolol and metoprolol and the BCS class III drugs cimetidine, atenolol, and amoxicillin, and to perform in silico bioequivalence studies to assess the feasibility of extending biowaivers to BCS class III drugs. The drug absorption from the gastrointestinal tract was predicted using physicochemical and pharmacokinetic properties of test drugs provided by GastroPlus (version 6.0). Virtual trials with a 200 mL dose volume at different drug release rates (T(85%) = 15 to 180 min) were performed to predict the oral absorption (C(max) and AUC(0-inf)) of the above drugs. Both BCS class I drugs satisfied bioequivalence with regard to the release rates up to 120 min. The results with BCS class III drugs demonstrated bioequivalence using the prolonged release rate, T(85%) = 45 or 60 min, indicating that the dissolution standard for bioequivalence is dependent on the intestinal membrane permeability and permeability profile throughout the gastrointestinal tract. The results of GastroPlus simulations indicate that the dissolution rate of BCS class III drugs could be prolonged to the point where dissolution, rather than permeability, would control the overall absorption. For BCS class III drugs with intestinal absorption patterns

  7. Civilization III and Whole-Class Play in High School Social Studies

    Science.gov (United States)

    Lee, John K.; Probert, Jeffrey

    2010-01-01

    This study examined an 11th grade high school class as they played the game Civilization III. Over nine class sessions students played the game in support of other activities related to several predetermined and emergent topics in U. S. history. Gameplay was whole-class oriented and involved students taking turns at the computer controlling…

  8. Skeletal class III camouflage by mandibular incisor extraction: A case report

    Directory of Open Access Journals (Sweden)

    Janardhanan Kumaresan

    2014-01-01

    Full Text Available Treatment planning in orthodontics plays a key role in determining the successful treatment of any kind of malocclusion. Skeletal class III malocclusions are generally difficult to treat because of the complex nature of the skeletal and dental manifestations they produce. Mild to moderate skeletal class III malocclusions sometimes have an acceptable facial profile where orthodontic camouflage is possible. In this case report, camouflage of a mild skeletal class III is done by the extraction of a single mandibular incisor, which helped in maintaining the profile of the patient and also in the correction of crowding in the mandibular anterior region.

  9. FREQUENCY AND TYPES OF DENTOFACIAL ABNORMALITIES AMONG CHILDREN WITH NASAL SEPTUM DEFORMATIONS

    OpenAIRE

    Voliak, Yu. M.; Ozhohan, Z. R.

    2015-01-01

    Abnormalities of dentofacial system in children and adolescents take one of the first places among the diseases of the dentofacial area. Dentofacial system disorders occur from 60% to 90 % of cases in comorbidities of other body systems, especially ENT pathologies. Respiratory dysfunction and mouth breathing as a result belong to the most important etiological factors of dental arch narrowing.Difficulty in nasal breathing or “nasal obstruction” is a leading syndrome in rhinology. Being a mani...

  10. Increased expression of class III β-tubulin in castration-resistant human prostate cancer

    OpenAIRE

    Terry, S; Ploussard, G; Allory, Y; Nicolaiew, N; Boissière-Michot, F; Maillé, P; Kheuang, L; Coppolani, E; Ali, A.; Bibeau, F; Culine, S; Buttyan, R.; de la Taille, A; Vacherot, F

    2009-01-01

    Background: Class III β-tubulin (βIII-tubulin) is expressed in tissues of neuronal lineage and also in several human malignancies, including non-small-cell lung carcinoma, breast and ovarian cancer. Overexpression of βIII-tubulin in these tumours is associated with an unfavourable outcome and resistance to taxane-based therapies. At present, βIII-tubulin expression remains largely uncharacterised in prostate cancer. Methods: In this report, we evaluated the expression of βIII-tubulin in 138 d...

  11. 25 CFR 291.3 - When may an Indian tribe ask the Secretary to issue Class III gaming procedures?

    Science.gov (United States)

    2010-04-01

    ... III gaming procedures? 291.3 Section 291.3 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ECONOMIC ENTERPRISES CLASS III GAMING PROCEDURES § 291.3 When may an Indian tribe ask the Secretary to issue Class III gaming procedures? An Indian tribe may ask the Secretary to issue Class...

  12. 25 CFR 291.12 - Who will monitor and enforce tribal compliance with the Class III gaming procedures?

    Science.gov (United States)

    2010-04-01

    ... Class III gaming procedures? 291.12 Section 291.12 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR ECONOMIC ENTERPRISES CLASS III GAMING PROCEDURES § 291.12 Who will monitor and enforce tribal compliance with the Class III gaming procedures? The Indian tribe and the State may have an...

  13. Early class III occlusal tendency in children and its selective management

    Directory of Open Access Journals (Sweden)

    Kapur A

    2008-09-01

    Full Text Available Class III malocclusion may develop in children as a result of an inherent growth abnormality, i.e., true class III malocclusion, or as a result of premature occlusal contacts causing forward functional shift of the mandible, which is known as pseudo class III malocclusion. These cases, if not treated at the initial stage of development, interfere with normal growth of the skeletal bases and may result in severe facial deformities. The treatment should be carried out as early as possible with the aim of permitting normal growth. This paper deals with the selection of an appropriate treatment approach from the various current options available for early intervention in children developing class III occlusal tendencies; the different clinical features are depicted in the three case reports.

  14. Influence of children's dentofacial appearance on teacher expectations.

    Science.gov (United States)

    Shaw, W C; Humphreys, S

    1982-12-01

    The purpose of the study was to determine whether the presence of dentofacial anomaly in a child would unfavourably bias a schoolteacher's expectations of the child's scholastic potential, social relationships or personality. Black and white portrait photographs of an attractive boy and girl and an unattractive boy and girl were obtained and modified so that for each face, five different photographic versions were available. In each version, the child's face was standardized except that a different dentofacial arrangement was demonstrated. These were normal incisors, prominent incisors, missing lateral incisor, severely crowded incisors and unilateral cleft lip. Each photograph was attached to a school record card which presented a standardized educational history of an average pupil. The record cards were evaluated by 320 schoolteachers, uninformed as to the true nature of the investigation, and their assessments recorded on a questionnaire. The experimental procedure was such that the effect and interaction of different levels of facial attractiveness, different dentofacial arrangements, sex of photographed child, and sex of teacher could be analysed. The hypothesis, that children's faces with a normal dental appearance or high background facial attractiveness would gain preferential bias in teacher expectations, was not supported. PMID:6961980

  15. Maxillary canine-first premolar bilateral transposition in a Class III patient: A case report.

    Science.gov (United States)

    Potrubacz, Maciej Iancu; Tepedino, Michele; Chimenti, Claudio

    2016-05-01

    Tooth transposition is a rare dental anomaly that often represents a challenge for the clinician. The case of a girl with skeletal Class III malocclusion and concomitant maxillary canine-first premolar bilateral transposition, followed from 7 to 17 years of age, is presented. After a first phase of treatment aimed at resolving the Class III malocclusion, the transposition was maintained and the case finalized with a multibracket appliance. PMID:26280661

  16. Treatment in borderline class III malocclusion: orthodontic camouflage (extraction) versus orthognathic surgery

    OpenAIRE

    A-Bakr M Rabie; Wong, Ricky W.K; Min, G.U.

    2008-01-01

    AIMS: To investigate the differences in morphological characteristics of borderline class III patients who had undergone camouflage orthodontic treatment or orthognathic surgery, and to compare the treatment effects between these two modalities. MATERIALS AND METHODS: Cephalograms of 25 patients (13 orthodontic, 12 surgical) with class III malocclusion were analyzed. All had a pretreatment ANB angle greater than -5 masculine. RESULTS: Using discriminant analysis, only Holdaway angle was selec...

  17. Má oclusão Classe III de Angle com discrepância ântero-posterior acentuada Angle Class III malocclusion with severe anteroposterior disharmony

    Directory of Open Access Journals (Sweden)

    Marcos Alan Vieira Bittencourt

    2009-02-01

    Full Text Available A má oclusão Classe III de Angle é caracterizada por uma discrepância dentária ântero-posterior, que pode ou não estar acompanhada por alterações esqueléticas. Em geral, o aspecto facial fica bastante comprometido, sendo justamente esse fator, na maioria das vezes, que motiva o paciente a procurar pelo tratamento. Este caso foi apresentado à Diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO, representando a categoria 4, ou seja, uma má oclusão com discrepância ântero-posterior acentuada, Classe III, com ANB menor ou igual a -2º, como parte dos requisitos para a obtenção do título de Diplomado pelo BBO.Angle Class III malocclusion is characterized by an anteroposterior dental discrepancy which may or may not be accompanied by skeletal changes. In general, distressed by a significantly compromised facial aspect, patients tend to seek treatment. This case was presented to the Brazilian Board of Orthodontics and Facial Orthopedics (BBO, as representative of Category 4, i.e., a malocclusion with severe anteroposterior discrepancy, Class III, and ANB Angle equal to or smaller than -2º, as part of the requirements for obtaining the BBO Diploma.

  18. Treatment Options for Class III Malocclusion in Growing Patients with Emphasis on Maxillary Protraction

    Science.gov (United States)

    Azamian, Zeinab; Shirban, Farinaz

    2016-01-01

    It is very difficult to diagnose and treat Class III malocclusion. This type of malocclusion involves a number of cranial base and maxillary and mandibular skeletal and dental compensation components. In Class III malocclusion originating from mandibular prognathism, orthodontic treatment in growing patients is not a good choice and in most cases orthognathic surgery is recommended after the end of growth. Approximately 30–40% of Class III patients exhibit some degree of maxillary deficiency; therefore, devices can be used for maxillary protraction for orthodontic treatment in early mixed dentition. In cases in which dental components are primarily responsible for Class III malocclusion, early therapeutic intervention is recommended. An electronic search was conducted using the Medline database (Entrez PubMed), the Cochrane Collaboration Oral Health Group Database of Clinical Trials, Science Direct, and Scopus. In this review article, we described the treatment options for Class III malocclusion in growing patient with an emphasis on maxillary protraction. It seems that the most important factor for treatment of Class III malocclusion in growing patient is case selection. PMID:27144056

  19. Orthodontic-surgical treatment of the skeletal class III malocclusion: A case report

    Directory of Open Access Journals (Sweden)

    Stojanović Ljiljana S.

    2013-01-01

    Full Text Available Background. Class III malocclusions are considered to be ones of the most difficult problems to treat. Their causes are multifactorial and include genetic and/or environmental factors. Class III malocclusions are generally classified into 2 categories: skeletal and dental. The diagnosis is important due to the different treatment approaches. Generally a dental class III can be treated with orthodontics alone, while a true skeletal class III requires a combination of orthodontics and surgery. Case report. We presented a female patient with skeletal Class III malocclusion. The treatment was complete with positive overbite and acceptable occlusion using a combination of fixed orthodontic appliance treatment as well as the surgical operation. The patient was happy with her new appearance and function. Conclusion. Class III discrepancy should be diagnosed and classified according to its etiology and treated with appropriate surgery, including, if necessary, not only mandibular, but also maxillary surgery, in order to achieve a normal facial appearance. In any case, as the field of orthodontics continues to develop technologically and philosophically, we can expect that advances in diagnosis and treatment planning are imminent and inevitable.

  20. Assessment of technical documentation of Class III medical devices

    NARCIS (Netherlands)

    Roszek B; de Bruijn ACP; Pot JWGA; van Drongelen AW; BMT; vgc

    2010-01-01

    Europese regelgeving vereist dat fabrikanten van medische hulpmiddelen een dossier opstellen waaruit blijkt dat het hulpmiddel veilig en functioneel is. De kwaliteit van dossiers van de hoogste risicoklasse medische hulpmiddelen, klasse III, laat evenwel te wensen over. Dit blijkt uit onderzoek va

  1. Articulación de fones en individuos clase esqueletal I,II y III Speech patterns in skeletal class I, II and III subjects

    Directory of Open Access Journals (Sweden)

    Pía Villanueva

    2009-09-01

    Full Text Available OBJETIVO: determinar los patrones de articulación de fones consonánticos en sujetos de habla española chilena clases I, II y III esqueletal; comparar las diferencias fonéticas que existan entre clases esqueletales. MÉTODOS: se seleccionaron 54 individuos que cumplían con los criterios de inclusión determinados mediante un examen clínico intraoral y a través del análisis de Ricketts, y se conformaron los grupos de estudio de pacientes clases esqueletales I, II y III. Se les realizó un examen fonoarticulatorio estandarizado para determinar los fones modificados y el patrón articulatorio compensatorio realizado. RESULTADOS: se observaron cambios en el punto de articulación de fones consonánticos en las tres clases esqueletales, con diferencias significativas en los grupos de fones anteriores y medios entre pacientes clases I y II, sólo en el grupo de los fones anteriores entre pacientes I y III. Entre pacientes clases II y III no se observaron diferencias significativas. Se reportan modificaciones y compensaciones cualitativamente distintas entre las clases esqueletales. CONCLUSIONES: en relación a pacientes clase I, los pacientes clase II o III, presentan distinto grado de modificación en el punto de articulación de fones consonánticos. Las diferencias observadas se relacionan con los patrones esqueletales propios de cada clase.PURPOSE: to determine the consonant phonemes articulation patterns in Chilean skeletal class I, II and III Spanish speakers and compare their phonetic differences. METHODS: fifty-four skeletal class I, II and III subjects were selected, based on intraoral clinical examination and Ricketts cephalometric analysis, constituting the study groups. A standardized phonoarticulatory test was applied to each patient to determine the modified phonemes and their compensatory patterns. RESULTS: the findings indicate changes in articulation in all three groups. Significant differences were found in anterior and medium

  2. Viral Class 1 RNase III Involved in Suppression of RNA Silencing

    OpenAIRE

    Kreuze, Jan F.; Savenkov, Eugene I.; Cuellar, Wilmer; Li, Xiangdong; Valkonen, Jari P. T.

    2005-01-01

    Double-stranded RNA (dsRNA)-specific endonucleases belonging to RNase III classes 3 and 2 process dsRNA precursors to small interfering RNA (siRNA) or microRNA, respectively, thereby initiating and amplifying RNA silencing-based antiviral defense and gene regulation in eukaryotic cells. However, we now provide evidence that a class 1 RNase III is involved in suppression of RNA silencing. The single-stranded RNA genome of sweet potato chlorotic stunt virus (SPCSV) encodes an RNase III (RNase3)...

  3. A benefit-risk assessment of class III antiarrhythmic agents

    DEFF Research Database (Denmark)

    Brendorp, Bente; Pedersen, Oledyg; Torp-Pedersen, Christian;

    2002-01-01

    With beta-blockers as the exception, increasing doubt is emerging on the value of antiarrhythmic drug therapy following a series of trials that have either shown no mortality benefit or even an excess mortality. Vaughan Williams class I drugs are generally avoided in patients with structural hear...

  4. A radiographic study of temporomandibular joints in skeletal class III malocclusion

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sung Eun; Kim, Kae Duk [Chosun University College of Medicine, Kwangju (Korea, Republic of)

    2003-06-15

    To investigate the differences between the position of the mandibular condyles in temporomandibular joints of patients presenting with normal occlusion and skeletal class III malocclusion. Forty-two subjects with normal occlusion and thirty-seven subjects exhibiting skeletal class III malocclusion prior to orthodontic treatment were included in the study. Transcranial radiographs of each subject were taken at centric occlusion and 1 inch mouth opening. The positional relationship between the mandibular condyles with articular fossae and articular eminences at two positional states were evaluated and analyzed statistically. The mandibular condyles of the skeletal class III malocclusion group were found to be located more anteriorly from the center of the articular fossae compared to the normal occlusion group in centric occlusion. The mandibular condyles of the skeletal Class III malocclusion group were located more superiorly from the middle of articular height than those of the normal occlusion group in centric occlusion. However, these differences were not statistically significant. At 1 inch mouth opening, the mandibular condyles of the skeletal class III malocclusion group were placed more posteriorly from the articular eminences than those of the normal occlusion group. The mean angle of the articular eminence posterior slope were 56.51 .deg. {+-} 6.29 .deg. in the normal occlusion group and 60.37 .deg. {+-} 6.26 .deg. in the skeletal Class III malocclusion group. The mandibular condyles of the skeletal Class III malocclusion group were placed more anteriorly at centric occlusion and more posteriorly at 1 inch mouth opening when compared with those of the normal occlusion group.

  5. A radiographic study of temporomandibular joints in skeletal class III malocclusion

    International Nuclear Information System (INIS)

    To investigate the differences between the position of the mandibular condyles in temporomandibular joints of patients presenting with normal occlusion and skeletal class III malocclusion. Forty-two subjects with normal occlusion and thirty-seven subjects exhibiting skeletal class III malocclusion prior to orthodontic treatment were included in the study. Transcranial radiographs of each subject were taken at centric occlusion and 1 inch mouth opening. The positional relationship between the mandibular condyles with articular fossae and articular eminences at two positional states were evaluated and analyzed statistically. The mandibular condyles of the skeletal class III malocclusion group were found to be located more anteriorly from the center of the articular fossae compared to the normal occlusion group in centric occlusion. The mandibular condyles of the skeletal Class III malocclusion group were located more superiorly from the middle of articular height than those of the normal occlusion group in centric occlusion. However, these differences were not statistically significant. At 1 inch mouth opening, the mandibular condyles of the skeletal class III malocclusion group were placed more posteriorly from the articular eminences than those of the normal occlusion group. The mean angle of the articular eminence posterior slope were 56.51 .deg. ± 6.29 .deg. in the normal occlusion group and 60.37 .deg. ± 6.26 .deg. in the skeletal Class III malocclusion group. The mandibular condyles of the skeletal Class III malocclusion group were placed more anteriorly at centric occlusion and more posteriorly at 1 inch mouth opening when compared with those of the normal occlusion group.

  6. A roentgenocephalometric study on the condylar displacement in angle's class I and III malocclusion

    International Nuclear Information System (INIS)

    The purpose of this investigation was to know correlation of mean values between centric occlusion and centric relation by the cephalogram in Angle's Class I and III malocclusion subjects. 22 adults with Angle's Class I malocclusion (17 men and 5 women, 21 to 27 years of age) and 14 adult with Angle's class III malocclusion (10 men and 4 women, 21 to 27 years of age) were selected form the dental students in Yonsei University. Each subject was given two lateral cephalometric radiographics and cephalometric analysis was performed. All data form these analyses was recorded and statistically processed with CYBER computer system. The results were obtained as follows: 1. There was a strong positive correlation between centric occlusion and centric relation in all subjects with Angle's Class I and III malocclusion. 2. In Angle's Class I malocclusion, measurements in lower facial height revealed significant difference between centric occlusion and centric relation (p<0.05). 3.When the mandible was movement was 1.27 mm (0.2-2.8 mm) in Angle's Class I malocclusion, 1.70 mm(0.55-4.15 mm) in Angle's Class III malocclusion, and 1.44 mm (0.2- 4.15 mm) in all subjects.

  7. Glass ionomer cement as an occlusive barrier in Class III furcation defect

    Directory of Open Access Journals (Sweden)

    Rameshwari Singhal

    2011-01-01

    Full Text Available Predicting the prognosis of molars that have experienced furcation invasion, is often a frustrating experience to the dental clinician and disappointing report to the patient involved. Although multiple treatment modalities have been attempted to retain teeth with severe furcation invasion, clinical success has not been predictable. A case report involving the use of glass ionomer cement (GIC as an occlusive barrier in the management of Class III furcation defect involving mandibular first molar is presented. A literature review on the subject matter was conducted using Medline, Google search engines, and manual library search. GIC restoration of Class III furcation invasion gives a satisfactory result. Surgical and nonsurgical treatment options are available for the management of the condition. GIC as an occlusive barrier in Class III furcation invasion is an economical and less invasive treatment option. It also makes home care easy for the patient.

  8. Cephalometric assessment of maxillary length in Serbian children with skeletal class III

    Directory of Open Access Journals (Sweden)

    Stojanović Zdenka

    2013-01-01

    Full Text Available Background/Aim. Malocclusion of skeletal class III is a complex irregularity of sagittal inter-jaw relationship, which is due to irregularities of sagittal position of one or both of the jaw bones, which is often associated with disproportionate ratio of their length. The aim of this study was to determine whether the length of the jaw of children with skeletal class III in the period of mixed dentition was changed. Methods. Fifty children with skeletal class III and the same number of those with skeletal class I, of both sexes, have been selected on the basis of cephalometric analysis of profile tele-x-ray of the head. All the children aged 6-12 had mixed dentition, and were divided according to sex and age into three subgroups within each group. The length of maxilla, mandible and cranial base were measured. Proportions among the lengths measured within each group were found and difference significance in the measured lengths and their proportions among groups and subgroups were evaluated. Results. The children with skeletal class III, compared with the findings in the control group, had significantly lower values of maxillary length, total maxillary length, as well as lower values of their lengths in proportion to lengths of the front or the total length of cranial base and in proportion to mandibular lengths (p < 0.05. Among the patients of different sexes, both in the test and the control group, a significant difference in the values of the measured lengths was found. Conclusion. The children with skeletal class III have significantly shorter maxilla than those with skeletal class I.

  9. Management of skeletal Class III malocclusion with face mask therapy and comprehensive orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Kirthika Muthukumar

    2016-01-01

    Full Text Available Orthopedic correction of skeletal Class III malocclusion in a growing patient is crucial as it can circumvent future surgical procedures. Further, as surgery is done only at a later stage, early treatment helps to avoid the detrimental effects produced by the facial disfigurement on the patient's social life. This case report describes the treatment of a child aged 9 years 6 months who had a skeletal Class III malocclusion. The treatment plan involved the use of a reverse pull headgear (facemask and multibracket appliance therapy resulting in successful correction of the malocclusion. The treatment results were highly satisfactory resulting in improved facial esthetics, a skeletal Class I with a Dental Class I molar and canine relationship, an ideal overjet and overbite. Thus, dentoalveolar camouflage, if done in properly selected cases, alleviates the need for surgical intervention. The patient is being monitored until the end of growth to ensure the stability of treatment results.

  10. Management of skeletal Class III malocclusion with face mask therapy and comprehensive orthodontic treatment.

    Science.gov (United States)

    Muthukumar, Kirthika; Vijaykumar, N M; Sainath, M C

    2016-01-01

    Orthopedic correction of skeletal Class III malocclusion in a growing patient is crucial as it can circumvent future surgical procedures. Further, as surgery is done only at a later stage, early treatment helps to avoid the detrimental effects produced by the facial disfigurement on the patient's social life. This case report describes the treatment of a child aged 9 years 6 months who had a skeletal Class III malocclusion. The treatment plan involved the use of a reverse pull headgear (facemask) and multibracket appliance therapy resulting in successful correction of the malocclusion. The treatment results were highly satisfactory resulting in improved facial esthetics, a skeletal Class I with a Dental Class I molar and canine relationship, an ideal overjet and overbite. Thus, dentoalveolar camouflage, if done in properly selected cases, alleviates the need for surgical intervention. The patient is being monitored until the end of growth to ensure the stability of treatment results. PMID:27041912

  11. Load Flow and Short Circuit Analysis of the Class III Power System of HANARO

    International Nuclear Information System (INIS)

    The planning, design, and operation of electric power system require engineering studies to assist in the evaluation of the system performance, reliability, safety and economics. The Class III power of HANARO supplies power for not only HANARO but also RIPF and IMEF. The starting current of most ac motors is five to ten times normal full load current. The loads of the Class III power are connected in consecutive orders at an interval for 10 seconds to avoid excessive voltage drop. This technical report deals with the load flow study and motor starting study for the Class III power of HANARO using ETAP(Electrical Transient Analyzer Program) to verify the capacity of the diesel generator. Short-circuit studies are done to determine the magnitude of the prospective currents flowing throughout the power system at various time intervals after a fault occurs. Short-circuit studies can be performed at the planning stage in order to help finalize the system layout, determine voltage levels, and size cables, transformers, and conductors. From this study, we verify the short circuit current capacity of air circuit breaker(ACB) and automatic transfer switch(ATS) of the Class III power

  12. Inheritance of craniofacial features in Colombian families with class III malocclusion

    Directory of Open Access Journals (Sweden)

    L Otero

    2010-02-01

    Full Text Available L Otero, L Quintero, D Champsaur, E SimancaPontificia Universidad Javeriana, Bogotá, ColombiaIntroduction: The inheritance of class III malocclusion has been well documented, but the inheritance of craniofacial structures in Colombian families with this malocclusion has been not yet reported.Patients and methods: The study sample of 25 families comprised 186 untreated orthodontic individuals from 8 to 60 years old. Pedigrees were drawn using Cyrillic software. Complete family histories for each proband were ascertained and the affection status of relatives was confirmed by lateral cephalograms and facial and dental photographs. Analysis of variance and odds ratio test for each parameter was performed to estimate inheritance from parents to offspring and to determine similar phenotypic features in relatives.Results: The analysis of the pedigrees suggests autosomal dominant inheritance. The craniofacial characteristics that showed more resemblance between parents and offspring were middle facial height, shorter anterior cranial base and mandibular prognathism. In contrast the protrusion of upper lip and maxillary retrusion were the phenotypic features that contributed to class III in the majority of families.Conclusion: Knowledge of the inheritance of craniofacial phenotypes in class III malocclusion will enable the design of new therapies to treat this malocclusion.Keywords: inheritance, craniofacial, phenotype, class III malocclusion

  13. Lanthanide(III) Complexes of DOTA-Glycoconjugates: A Potential New Class of Lectin-Mediated Medical Imaging Agents

    OpenAIRE

    André, João P.; Geraldes, Carlos F. G. C.; Martins, José A.; Merbach, André E.; Prata, Maria I. M.; Santos, Ana C; Lima, João J. P. de; Tóth, Éva

    2004-01-01

    The synthesis and characterization of a new class of DOTA (1,4,7,10-tetrakis(carboxymethyl)-1,4,7,10-tetraazacyclododecane) monoamide-linked glycoconjugates (glucose, lactose and galactose) of different valencies (mono, di and tetra) and their Sm(III), Eu(III) and Gd(III) complexes are reported. The proton NMR spectrum of Eu(III)-DOTALac(III) shows the predominance of a single structural isomer of square antiprismatic geometry of the DOTA chelating moiety and fast ...

  14. Má oclusão de Classe I de Angle, com tendência à classe III esquelética, tratada com controle de crescimento Angle Class I malocclusion, with class III skeletal tendency, treated with growth control

    OpenAIRE

    Ademir Roberto Brunetto

    2009-01-01

    A má oclusão de Classe III de Angle é caracterizada por uma relação dentária anteroposterior inadequada, que pode ou não estar acompanhada de alterações esqueléticas. Em geral, o aspecto facial fica bastante comprometido, principalmente quando associada à deficiência no terço médio da face, sendo esse, na maioria das vezes, o principal fator que motiva o paciente a procurar tratamento. Este caso foi apresentado à Diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO), representa...

  15. Data on HLA class I/II profile in Brazilian pemphigus patients.

    Science.gov (United States)

    Franco Brochado, Maria José; Nascimento, Daniela Francisca; Saloum Deghaide, Neifi Hassan; Donadi, Eduardo Antonio; Roselino, Ana Maria

    2016-09-01

    Pemphigus are blistering autoimmune diseases related with genetic and environmental factors. Here we describe HLA genotyping in pemphigus patients. First, we review the HLA class I/II data on pemphigus reported in Brazilian samples and then present the HLA class I (-A, -B, -C) and class II (-DRB1, -DQA1, -DQB1) alleles related to susceptibility/resistance to pemphigus by comparing 86 patients with pemphigus foliaceus, 83 patients with pemphigus vulgaris, and 1592 controls from the northeastern region of the state of São Paulo, Southeastern Brazil. The data presented here are related to the manuscript "Differential HLA class I and class II associations in Pemphigus Foliaceus and Pemphigus Vulgaris patients from a prevalent Southeastern Brazilian region" Brochado et al. (2016) [1]. PMID:27331116

  16. Má oclusão de Classe I de Angle, com tendência à classe III esquelética, tratada com controle de crescimento Angle Class I malocclusion, with class III skeletal tendency, treated with growth control

    Directory of Open Access Journals (Sweden)

    Ademir Roberto Brunetto

    2009-10-01

    Full Text Available A má oclusão de Classe III de Angle é caracterizada por uma relação dentária anteroposterior inadequada, que pode ou não estar acompanhada de alterações esqueléticas. Em geral, o aspecto facial fica bastante comprometido, principalmente quando associada à deficiência no terço médio da face, sendo esse, na maioria das vezes, o principal fator que motiva o paciente a procurar tratamento. Este caso foi apresentado à Diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO, representando a categoria livre, como parte dos requisitos para a obtenção do título de Diplomado pelo BBO.Angle Class III malocclusion is characterized by an anteroposterior dental alteration, which might be accompanied by skeletal deformities. Usually, the facial aspect becomes aesthetically compromised, mostly when the middle third of the face is affected (this is the main reason why patients seek for treatment.This case was presented to the directorship of the Brazilian Board of Orthodontics and Facial Orthopedics (BBO, standing for the free category, as a part of the requirements to obtain the Board's Certificate.

  17. 40 CFR 144.21 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells.

    Science.gov (United States)

    2010-07-01

    ... recovery and hydrocarbon storage) and III wells. 144.21 Section 144.21 Protection of Environment... hydrocarbon storage) and III wells. (a) An existing Class I, II (except enhanced recovery and hydrocarbon... decision; or (9) For Class II wells (except enhanced recovery and hydrocarbon storage), five years...

  18. 76 FR 71600 - Renewal of Agency Information Collection for Class III Tribal-State Gaming Compact Process...

    Science.gov (United States)

    2011-11-18

    ... Bureau of Indian Affairs Renewal of Agency Information Collection for Class III Tribal- State Gaming... collection of information for the Class III Tribal State Gaming Compact Process. The information collection....eop.gov . Please send a copy of your comments to Paula L. Hart, Director, Office of Indian...

  19. Má oclusão Classe III de Angle com discrepância anteroposterior acentuada Angle Class III malocclusion with severe anteroposterior discrepancy

    Directory of Open Access Journals (Sweden)

    Carlos Alexandre Câmara

    2010-04-01

    Full Text Available O caso clínico apresentado refere-se ao tratamento de uma paciente com 36 anos, que apresentava uma má oclusão Classe III esquelética e dentária, com ausência dos caninos superiores. Foi realizado um tratamento ortodôntico-cirúrgico combinado, com avanço de maxila (Le Fort 1 e ajustes oclusais nos primeiros pré-molares superiores, que substituíram os caninos. Esse caso foi apresentado à Diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO, representando a categoria 4, ou seja, uma má oclusão com discrepância anterossuperior acentuada, como parte dos requisitos para a obtenção do título de Diplomado pelo BBO.This case report describes the treatment of a 36-year-old patient who presented a skeletal and dental Class III malocclusion and missing upper canines. The patient was treated with orthosurgical maxillary advancement (Le Fort 1 and occlusal adjustment of the first premolars, which replaced the canines. This case was presented to the Brazilian Board of Orthodontics and Facial Orthopedics (BBO, as representative of Category 4, i.e., malocclusion with severe anteroposterior discrepancy, as part of the requirements for obtaining the BBO Diploma.

  20. Dentofacial changes and oral health status in mentally challenged children

    Directory of Open Access Journals (Sweden)

    Bhowate Rahul

    2005-06-01

    Full Text Available The study was carried out on 69 mentally challenged individuals. They were subjected to detailed clinical evaluation for dentofacial abnormalities and oral health status. Of the 69 mentally handicapped individuals 27 had Downs syndrome and 42 had cerebral palsy. Characteristic facial abnormalities were seen in children with Downs syndrome. In cerebral palsy, fracture maxillary anteriors were more evident. All the Downs syndrome cases had abnormal TMJ movements but in cerebral palsy only 35.7% of individuals had abnormal TMJ movements. In both the groups, submandibular lymph adenopathy was reported. Present study revealed dental caries in 56.0% of the individuals. Fair clinical level of oral hygiene in 60% of the individuals was seen.

  1. Auditory characteristics of individuals with temporomandibular dysfunctions and dentofacial deformities

    Directory of Open Access Journals (Sweden)

    Tatiane Totta

    2013-10-01

    Full Text Available OBJECTIVE: To investigate whether there is any relationship between otological as well as vestibular symptoms, audiological findings and type of temporomandibular disorder (articular, muscular and mixed; and to check the distribution of the temporomandibular disorders (TMD dysfunction degree in the research population. METHODS: A retrospective study involving 30 patients of both sexes, aged between 18 and 49 years old, diagnosed with TMD and dentofacial deformities, who were subject to clinical evaluation (muscle palpation, auscultation of temporomandibular joint during mandibular motion and measurement of jaw movement, audiological testing (pure tone audiometry and immittance testing and two questionnaires, one on otological and vestibular symptoms and the other on TMD anamnesis. Based on both the anamnesis questionnaire and the clinical assessment, the subjects were divided according to the type and degree of TMD dysfunction (mild, moderate and severe, and compared regarding the occurrence of auditory signs and symptoms, vestibular symptoms and audiological findings according to TMD type. RESULTS: The anamnesis questionnaire demonstrated higher prevalence (83.33% of severe TMD. Subjects with mixed TMD had more complaints about hypoacusis than those with muscular TMD (p < 0.05. The results showed no change in either audiological and immittance testing for all assessed individuals. CONCLUSION: Otological symptoms are present in subjects with TMD and dentofacial deformities, regardless of the classification of TMD (articular, muscular or mixed. Those with mixed TMD may have higher incidence of complaints about hypoacusis than subjects with muscular TMD. Further studies are needed to investigate the relationship between otological symptoms and the different types of TMD.

  2. Combined orthognathic surgery and prosthetic treatment for class III skeletal malocclusion

    Directory of Open Access Journals (Sweden)

    Luka Dias Wellar

    2013-01-01

    Full Text Available This clinical report discusses the case of a partially edentulous patient with class III skeletal malocclusion, suffering from poor masticatory function and esthetic appearance caused by severe anteroposterior discrepancy between the dental arches and loss of occlusal vertical dimension. The functional and esthetic rehabilitation was performed with orthognathic surgery followed by prosthetic treatment using an overlay removable partial denture. At the end of the treatment, the patient was successfully rehabilitated, both functionally and esthetically, through reestablishment of the occlusal vertical dimension and correction of the anteroposterior discrepancy between the dental arches. The overlay removable partial denture is a simple and time-efficient alternative in the treatment of partially edentulous patients with class III skeletal malocclusions and small anteroposterior discrepancies between dental arches. Additionally, an esthetic smile and functional rehabilitation of the stomatognathic system was satisfactorily obtained with orthognathic surgery followed by prosthetic treatment.

  3. Compensatory treatment of Angle Class III malocclusion with anterior open bite and mandibular asymmetry

    Directory of Open Access Journals (Sweden)

    Marcio Costa Sobral

    2012-06-01

    Full Text Available Class III malocclusion is characterized by anterior posterior dental disharmony, either with or without skeletal discrepancies. Facial esthetics may be compromised to a greater or lesser degree, depending on the magnitude of the discrepancy, and is one of the main factors motivating individuals to seek orthodontic treatment. In adult patients, therapy may be performed by means of dental compensation, in simpler cases, or in more severe situations, by means of association between Orthodontics and Orthognathic Surgery. The present article is a clinical case report of a patient with a vertical facial pattern, Angle Class III malocclusion, with open bite and important facial asymmetry. The patient was treated in a compensatory manner with extractions, using extra-oral appliances on the mandibular arch with high pull, applying the principles of the Tweed-Merrifield technique. This case was presented to the Brazilian Board of Orthodontics and Facial Orthopedics (BBO as part of the requisites for becoming a BBO Diplomate.

  4. Angle Class I malocclusion with anterior negative overjet

    Science.gov (United States)

    de Souza, Paulo Ávila

    2016-01-01

    ABSTRACT This clinical case report describes the orthodontic treatment of an 8-year and 9-month old female patient with Angle Class I malocclusion, anterior crossbite and canine Class III relationship. Orthodontic treatment was carried out in two stages. The first one was orthopedic, while the second one included the use of a fixed appliance and the need for space gain for reshaping of maxillary lateral incisors. The two-stage treatment combined with multidisciplinary Restorative Cosmetic Dentistry allowed excellent esthetic and functional outcomes to be achieved. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as a requirement for the title of certified by the BBO. PMID:27275622

  5. Using Networks To Understand Medical Data: The Case of Class III Malocclusions

    OpenAIRE

    Scala, A.; P. Auconi; M. Scazzocchio; Caldarelli, G.; J. A. McNamara; Franchi, L

    2012-01-01

    A system of elements that interact or regulate each other can be represented by a mathematical object called a network. While network analysis has been successfully applied to high-throughput biological systems, less has been done regarding their application in more applied fields of medicine; here we show an application based on standard medical diagnostic data. We apply network analysis to Class III malocclusion, one of the most difficult to understand and treat orofacial anomaly. We ...

  6. Glass ionomer cement as an occlusive barrier in Class III furcation defect

    OpenAIRE

    Rameshwari Singhal

    2011-01-01

    Predicting the prognosis of molars that have experienced furcation invasion, is often a frustrating experience to the dental clinician and disappointing report to the patient involved. Although multiple treatment modalities have been attempted to retain teeth with severe furcation invasion, clinical success has not been predictable. A case report involving the use of glass ionomer cement (GIC) as an occlusive barrier in the management of Class III furcation defect involving mandibular first m...

  7. Characterizing Distributions of Class III Milk Prices: Implications for Risk Management

    OpenAIRE

    Wang, Dabin; Tomek, William G.

    2005-01-01

    Descriptive statistics and time-series econometric models are used to characterize the behavior of monthly fluid milk prices. Prices in April, May and June appear to be more variable than those in subsequent months, and the spring-time prices are perhaps skewed. Econometric models can capture the historical behavior of spot prices, but forecasts converge to the marginal distribution of the sample prices in about six months. Futures prices for Class III milk have the expected time-to-maturity ...

  8. Compensatory treatment of Angle Class III malocclusion with anterior open bite and mandibular asymmetry

    OpenAIRE

    Marcio Costa Sobral

    2012-01-01

    Class III malocclusion is characterized by anterior posterior dental disharmony, either with or without skeletal discrepancies. Facial esthetics may be compromised to a greater or lesser degree, depending on the magnitude of the discrepancy, and is one of the main factors motivating individuals to seek orthodontic treatment. In adult patients, therapy may be performed by means of dental compensation, in simpler cases, or in more severe situations, by means of association between Orthodontics ...

  9. Surgical-orthodontic treatment of Class III malocclusion with agenesis of lateral incisor and unerupted canine

    OpenAIRE

    Bruno Boaventura Vieira; Ana Carolina Meng Sanguino; Marilia Rodrigues Moreira; Elizabeth Norie Morizono; Mírian Aiko Nakane Matsumoto

    2013-01-01

    INTRODUCTION: Orthodontic-surgical treatment was performed in patient with skeletal Class III malocclusion due to exceeding mandibular growth. Patient also presented upper and lower dental protrusion, overjet of -3.0 mm, overbite of -1.0 mm, congenital absence of tooth #22, teeth #13 and supernumerary impaction, tooth #12 with conoid shape and partly erupted in supraversion, prolonged retention of tooth #53, tendency to vertical growth of the face and facial asymmetry. The discrepancy on the ...

  10. Orthodontic retreatment of a Class III patient with significant midline asymmetry and bilateral posterior crossbite

    OpenAIRE

    Brunetto, Ademir R.

    2015-01-01

    Posterior crossbite might cause serious long-term functional problems if not early treated. Nevertheless, in older patients, treatment might include palatal expansion in order to correct such malocclusion. In view of the above, this article aims at reporting late correction of bilateral posterior crossbite associated with Angle Class III malocclusion, right subdivision, with consequent midline shift (good skeletal pattern). The case was presented to the Brazilian Board of Orthodontics and Den...

  11. Free gingival graft in the treatment of class III gingival recession

    Directory of Open Access Journals (Sweden)

    Remya V

    2008-01-01

    Full Text Available Aim: The purpose of this study was to assess the success and predictability of root coverage and esthetics obtained with free gingival grafts (FGGs in the treatment of early class III gingival recessions for a period of 12 months. Materials and Methods: Ten patients contributed to 12 sites, each with early class III recession with interdental bone loss £4 mm from cemento enamel junction(CEJ. Clinical parameters recorded at baseline and at 1, 6, and 12 months were probing depth (PD, recession depth (RD, recession width (RW, and clinical attachment level (CAL. Results: Reduction of recession resulted in a significant gain in CAL and PD at the end of 12 months. A statistically significant mean root coverage of 41.25 ± 21.07% was obtained at the end of 12 months. A statistically significant improvement in Visual Analog Scale score was seen after a 12-month follow-up period. Conclusion: In a south Indian population, early class III gingival recessions treated with FGG procedures resulted in 40-50% root coverage with fairly acceptable esthetics.

  12. Má oclusão Classe III, com mordida cruzada posterior unilateral e assimetria facial Class III malocclusion with unilateral posterior crossbite and facial asymmetry

    OpenAIRE

    Silvio Rosan de Oliveira

    2010-01-01

    Este artigo relata o tratamento ortodôntico realizado em uma paciente adulta, com 36 anos de idade, portadora de um padrão esquelético e dentário de Classe III, com mordida cruzada posterior unilateral esquerda e assimetria mandibular, além de uma diferença relativamente grande entre máxima intercuspidação habitual (MIH) e relação cêntrica (RC). O tratamento foi realizado com expansão dentária superior, contração dentária inferior e descruzamento anterior, eliminando a diferença entre MIH e R...

  13. The Position of Hyoici Bone in Skeletal Class I, II and III Patients

    Directory of Open Access Journals (Sweden)

    Ravanmehr H

    2000-06-01

    Full Text Available In this investigation, the position of hyoid bone was compared in three skeletal groups of class I, II and III. The study was based on evaluating 77 lateral cephalometric radiographs, 40 girls and 37 boys, which were divided into 3 groups. Group 1, 2, and 3 consist of 26, 25, and 26 radiographs. 19 cephalometric landmarks and 10 planes were used in order to tracing the radiographs. In all patients, 9 skeletal and 4 cervical vertebrae parameters were measured to determine the hyoid bone. These parameters were compared between three skeletal groups regardless of sex and then, in another statistical analysis, parameters were compared based on patients sex. Statistical analysis showed that in class III patients, the hyoid bone was positioned more anteriorly than two other groups. Also in this group, the hyoid bone had less inclination and it was more horizontal in relation to mandibular plane. In skeletal class II patients this bone was positioned more superiorly than two other groups. Due to these findings it can be concluded that perimandibular muscles and bones could affect the growth of mandible. In addition, comparison of the parameters between two sexes revealed that the hyoid bone was positioned more anteriorly and inferiorly in boys. Also it was shown that in the girls, the position of hyoid bone was closer to the position of this bone in skeletal class I patients.

  14. Size of lower jaw as an early indicator of skeletal class III development

    Directory of Open Access Journals (Sweden)

    Stojanović Zdenka

    2008-01-01

    Full Text Available Background/Aim. Malocclusion of skeletal class III is a complex abnormality, with a characteristic sagital position of the lower jaw in front of the upper one. A higher level of prognatism of the lower jaw in relation to the upper one can be the consequence of its excessive length. The aim of this study was to find the differences in the length of the lower jaw in the children with skeletal class III and the children with normal sagital interjaw relation (skeletal class I in the period of mixed dentition. Methods. After clinical and x-ray diagnostics, profile tele-x-rays of the head were analyzed in 60 examinees with mixed dentition, aged from 6 to 12 years. The examinees were divided into two groups: group 1 - the children with skeletal class III and group 2 - the children with skeletal class I. The length of the lower jaw, upper jaw and cranial base were measured. The proportional relations between the lengths measured within each group were established and the level of difference in the lengths measured and their proportions between the groups were estimated. Results. No significant difference between the groups was found in the body length, ramus and the total length of the lower jaw. Proportional relation between the body length and the length of the lower jaw ramus and proportional relation between the forward cranial base and the lower jaw body were not significantly different. A significant difference was found in proportional relations of the total length of the lower jaw with the total lengths of cranial base and the upper jaw and proportional relation of the length of the lower and upper jaw body. Conclusion. Of all the analyzed parameters, the following were selected as the early indicators of the development of skeletal class III on the lower jaw: greater total length of the lower jaw, proportional to the total lengths of cranial base and the upper jaw, as well as greater length of the lower jaw body, proportional to the length of

  15. Early orthopedic correction of skeletal Class III malocclusion using combined reverse twin block and face mask therapy

    Directory of Open Access Journals (Sweden)

    Vinay Kumar Chugh

    2015-01-01

    Full Text Available A 6-year 8-month-old girl presented with a moderate Class III malocclusion characterized by mid-face deficiency and an anterior cross bite. In the first phase, the patient was treated with combination of reverse twin block and facemask therapy. In phase two, fixed appliances were placed in the permanent dentition. The post treatment results were good and a favorable growth tendency could be observed. The correction of the Class III malocclusion occurred by a combination of skeletal and dental improvements. This report shows successful correction of skeletal Class III malocclusion in the early transitional dentition using combination therapy.

  16. Base of the skull morphology and Class III malocclusion in patients with unilateral cleft lip and palate

    Directory of Open Access Journals (Sweden)

    Mariana Maciel Tinano

    2015-02-01

    Full Text Available OBJECTIVE: The aim of the present study was to determine the morphological differences in the base of the skull of individuals with cleft lip and palate and Class III malocclusion in comparison to control groups with Class I and Class III malocclusion. METHODS: A total of 89 individuals (males and females aged between 5 and 27 years old (Class I, n = 32; Class III, n = 29; and Class III individuals with unilateral cleft lip and palate, n = 28 attending PUC-MG Dental Center and Cleft Lip/Palate Care Center of Baleia Hospital and PUC-MG (CENTRARE were selected. Linear and angular measurements of the base of the skull, maxilla and mandible were performed and assessed by a single calibrated examiner by means of cephalometric radiographs. Statistical analysis involved ANCOVA and Bonferroni correction. RESULTS: No significant differences with regard to the base of the skull were found between the control group (Class I and individuals with cleft lip and palate (P > 0.017. The cleft lip/palate group differed from the Class III group only with regard to CI.Sp.Ba (P = 0.015. Individuals with cleft lip and palate had a significantly shorter maxillary length (Co-A in comparison to the control group (P < 0.001. No significant differences were found in the mandible (Co-Gn of the control group and individuals with cleft lip and palate (P = 1.000. CONCLUSION: The present findings suggest that there are no significant differences in the base of the skull of individuals Class I or Class III and individuals with cleft lip and palate and Class III malocclusion.

  17. 40 CFR Figure C-2 to Subpart C of... - Illustration of the Slope and Intercept Limits for Class II and Class III PM2.5 Candidate...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Illustration of the Slope and Intercept Limits for Class II and Class III PM2.5 Candidate Equivalent Methods C Figure C-2 to Subpart C of Part 53... Methods and Reference Methods Pt. 53, Subpt. C, Fig. C-2 Figure C-2 to Subpart C of Part...

  18. Bacillus subtilis class Ib ribonucleotide reductase is a dimanganese(III)-tyrosyl radical enzyme.

    Science.gov (United States)

    Zhang, Yan; Stubbe, Joanne

    2011-06-28

    Bacillus subtilis class Ib ribonucleotide reductase (RNR) catalyzes the conversion of nucleotides to deoxynucleotides, providing the building blocks for DNA replication and repair. It is composed of two proteins: α (NrdE) and β (NrdF). β contains the metallo-cofactor, essential for the initiation of the reduction process. The RNR genes are organized within the nrdI-nrdE-nrdF-ymaB operon. Each protein has been cloned, expressed, and purified from Escherichia coli. As isolated, recombinant NrdF (rNrdF) contained a diferric-tyrosyl radical [Fe(III)(2)-Y(•)] cofactor. Alternatively, this cluster could be self-assembled from apo-rNrdF, Fe(II), and O(2). Apo-rNrdF loaded using 4 Mn(II)/β(2), O(2), and reduced NrdI (a flavodoxin) can form a dimanganese(III)-Y(•) [Mn(III)(2)-Y(•)] cofactor. In the presence of rNrdE, ATP, and CDP, Mn(III)(2)-Y(•) and Fe(III)(2)-Y(•) rNrdF generate dCDP at rates of 132 and 10 nmol min(-1) mg(-1), respectively (both normalized for 1 Y(•)/β(2)). To determine the endogenous cofactor of NrdF in B. subtilis, the entire operon was placed behind a Pspank(hy) promoter and integrated into the B. subtilis genome at the amyE site. All four genes were induced in cells grown in Luria-Bertani medium, with levels of NrdE and NrdF elevated 35-fold relative to that of the wild-type strain. NrdE and NrdF were copurified in a 1:1 ratio from this engineered B. subtilis. The visible, EPR, and atomic absorption spectra of the purified NrdENrdF complex (eNrdF) exhibited characteristics of a Mn(III)(2)-Y(•) center with 2 Mn/β(2) and 0.5 Y(•)/β(2) and an activity of 318-363 nmol min(-1) mg(-1) (normalized for 1 Y(•)/β(2)). These data strongly suggest that the B. subtilis class Ib RNR is a Mn(III)(2)-Y(•) enzyme. PMID:21561096

  19. Diagnosis and conservative treatment of skeletal Class III malocclusion with anterior crossbite and asymmetric maxillary crowding.

    Science.gov (United States)

    Tseng, Linda L Y; Chang, Chris H; Roberts, W Eugene

    2016-04-01

    A man, aged 28 years 9 months, came for an orthodontic consultation for a skeletal Class III malocclusion (ANB angle, -3°) with a modest asymmetric Class II and Class III molar relationship, complicated by an anterior crossbite, a deepbite, and 12 mm of asymmetric maxillary crowding. Despite the severity of the malocclusion (Discrepancy Index, 37), the patient desired noninvasive camouflage treatment. The 3-Ring diagnosis showed that treatment without extractions or orthognathic surgery was a viable approach. Arch length analysis indicated that differential interproximal enamel reduction could resolve the crowding and midline discrepancy, but a miniscrew in the infrazygomatic crest was needed to retract the right buccal segment. The patient accepted the complex, staged treatment plan with the understanding that it would require about 3.5 years. Fixed appliance treatment with passive self-ligating brackets, early light short elastics, bite turbos, interproximal enamel reduction, and infrazygomatic crest retraction opened the vertical dimension of the occlusion, improved the ANB angle by 2°, and achieved excellent alignment, as evidenced by a Cast Radiograph Evaluation score of 28 and a Pink and White dental esthetic score of 3. PMID:27021460

  20. Surgical-orthodontic treatment of Class III malocclusion with agenesis of lateral incisor and unerupted canine

    Directory of Open Access Journals (Sweden)

    Bruno Boaventura Vieira

    2013-06-01

    Full Text Available INTRODUCTION: Orthodontic-surgical treatment was performed in patient with skeletal Class III malocclusion due to exceeding mandibular growth. Patient also presented upper and lower dental protrusion, overjet of -3.0 mm, overbite of -1.0 mm, congenital absence of tooth #22, teeth #13 and supernumerary impaction, tooth #12 with conoid shape and partly erupted in supraversion, prolonged retention of tooth #53, tendency to vertical growth of the face and facial asymmetry. The discrepancy on the upper arch was -2.0 mm and -5.0 mm on the lower arch. METHODS: The pre-surgical orthodontic treatment was performed with extractions of the teeth #35 and #45. On the upper arch, teeth #53, #12 and supernumerary were extracted to accomplish the traction of the impacted canine. The spaces of the lower extractions were closed with mesialization of posterior segment. After aligning and leveling the teeth, extractions spaces closure and correct positioning of teeth on the bone bases, the correct intercuspation of the dental arch, with molars and canines in Angle's Class I, coincident midline, normal overjet and overbite and ideal torques, were evaluated through study models. The patient was submitted to orthognathic surgery and then the post-surgical orthodontic treatment was finished. RESULTS: The Class III malocclusion was treated establishing occlusal and facial normal standards.

  1. Long-term stability of surgical-orthodontic correction of class III malocclusions with long-face syndrome

    OpenAIRE

    Gallego-Romero, David; Llamas-Carrera, José M.; Torres-Lagares, Daniel; Paredes, Vanessa; Espinar, Eduardo; Guevara, Eduardo; Gutiérrez-Pérez, José L.

    2011-01-01

    Objectives: In the first place, to evaluate skeletal changes of the maxilla and mandible induced by surgical-orthodontic correction of malocclusions class III with long-face syndrome and secondly, to analyze the stability of these skeletal changes in the long term (more than 6 years). Design of Study: A retrospective, unicentric and longitudinal study of 19 patients who had undergone surgical and orthodontic therapy for class III skeletal malocclusion with long-face syndrome was undertaken. A...

  2. Má oclusão Classe III, com mordida cruzada posterior unilateral e assimetria facial Class III malocclusion with unilateral posterior crossbite and facial asymmetry

    Directory of Open Access Journals (Sweden)

    Silvio Rosan de Oliveira

    2010-10-01

    Full Text Available Este artigo relata o tratamento ortodôntico realizado em uma paciente adulta, com 36 anos de idade, portadora de um padrão esquelético e dentário de Classe III, com mordida cruzada posterior unilateral esquerda e assimetria mandibular, além de uma diferença relativamente grande entre máxima intercuspidação habitual (MIH e relação cêntrica (RC. O tratamento foi realizado com expansão dentária superior, contração dentária inferior e descruzamento anterior, eliminando a diferença entre MIH e RC. O resultado obtido foi pautado sobre um diagnóstico criterioso e um planejamento de compensação ortodôntica, sem intervenção cirúrgica nos maxilares, por solicitação da paciente. Este caso foi apresentado à Diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO, representando a categoria 5, ou seja, má oclusão com problema transverso, apresentando pelo menos um quadrante em cruzamento, como parte dos requisitos para obtenção do título de Diplomado pelo BBO.This article reports on the orthodontic treatment performed on a 36-year-old female patient with skeletal and dental Class III pattern, presenting with a left unilateral posterior crossbite and mandibular asymmetry, and a relatively significant difference between maximum intercuspation (MIC and centric relation (CR. The treatment was performed with maxillary dental expansion, mandibular dental contraction and anterior crossbite correction, eliminating the difference between MIC and CR. Results were based on careful diagnosis and planning of orthodontic compensation without surgical intervention in the maxilla, at the request of the patient. This case was presented to the Brazilian Board of Orthodontics and Facial Orthopedics (BBO as representative of Category 5, i.e., malocclusion with a transverse problem, presenting with a crossbite in at least one of the quadrants, as part of the requirements for obtaining the BBO Certificate.

  3. 40 CFR 147.1653 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.1653 Section 147.1653 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  4. 40 CFR 147.903 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.903 Section 147.903 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  5. 40 CFR 147.1153 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.1153 Section 147.1153 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  6. 40 CFR 147.1353 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.1353 Section 147.1353 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  7. 40 CFR 147.303 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.303 Section 147.303 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  8. 40 CFR 147.103 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.103 Section 147.103 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  9. 40 CFR 147.2153 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.2153 Section 147.2153 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  10. 40 CFR 147.1953 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.1953 Section 147.1953 Protection of... enhanced recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection...

  11. 40 CFR 147.1453 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.1453 Section 147.1453 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  12. 40 CFR 147.253 - Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Existing Class I, II (except enhanced recovery and hydrocarbon storage) and III wells authorized by rule. 147.253 Section 147.253 Protection of... recovery and hydrocarbon storage) and III wells authorized by rule. Maximum injection pressure. The...

  13. LONG TERM EFFECTS OF SKELETAL CLASS III TREATMENT: A CASE REPORT

    OpenAIRE

    GÜNGÖR, AHMET YALÇIN; Turkkahraman, Hakan

    2013-01-01

    Even class III treatment in pubertal ages is more difficult than treatment of other maloclusions, its results could be change later especially due to late mandibular growth. This case describes stabile results of a patient, at the last period of her growth and development, from 14 to 19 years old. Our patient was a 14.3 years old girl at Ru period of skeletal maturation. Extraorally, patient had a concave profile, lower midline was symmetric, upper midline was 3mm dislocated to right from ...

  14. Correction of transverse maxillary deficiency and anterior open bite in an adult Class III skeletal patient

    Directory of Open Access Journals (Sweden)

    Prerna Hoogan Teja

    2016-01-01

    Full Text Available Transverse maxillary deficiency may be associated with sagittal or vertical problems of the maxilla or mandible. It may contribute to unilateral or bilateral posterior crossbite, anterior dental crowding, and unesthetic black buccal corridors on smiling. An adequate transverse dimension is important for stable and proper functional occlusion. Surgically, assisted rapid palatal expansion has been the treatment of choice to resolve posterior crossbite in skeletally mature patients. The following case report presents an adult Class III skeletal patient with an anterior open bite and bilateral posterior crossbite which was treated by surgically assisted rapid maxillary expansion with satisfactory outcomes.

  15. Study of Class I and Class III Polyhydroxyalkanoate (PHA) Synthases with Substrates Containing a Modified Side Chain.

    Science.gov (United States)

    Jia, Kaimin; Cao, Ruikai; Hua, Duy H; Li, Ping

    2016-04-11

    Polyhydroxyalkanoates (PHAs) are carbon and energy storage polymers produced by a variety of microbial organisms under nutrient-limited conditions. They have been considered as an environmentally friendly alternative to oil-based plastics due to their renewability, versatility, and biodegradability. PHA synthase (PhaC) plays a central role in PHA biosynthesis, in which its activity and substrate specificity are major factors in determining the productivity and properties of the produced polymers. However, the effects of modifying the substrate side chain are not well understood because of the difficulty to accessing the desired analogues. In this report, a series of 3-(R)-hydroxyacyl coenzyme A (HACoA) analogues were synthesized and tested with class I synthases from Chromobacterium sp. USM2 (PhaCCs and A479S-PhaCCs) and Caulobacter crescentus (PhaCCc) as well as class III synthase from Allochromatium vinosum (PhaECAv). It was found that, while different PHA synthases displayed distinct preference with regard to the length of the alkyl side chains, they could withstand moderate side chain modifications such as terminal unsaturated bonds and the azide group. Specifically, the specific activity of PhaCCs toward propynyl analogue (HHxyCoA) was only 5-fold less than that toward the classical substrate HBCoA. The catalytic efficiency (kcat/Km) of PhaECAv toward azide analogue (HABCoA) was determined to be 2.86 × 10(5) M(-1) s(-1), which was 6.2% of the value of HBCoA (4.62 × 10(6) M(-1) s(-1)) measured in the presence of bovine serum albumin (BSA). These side chain modifications may be employed to introduce new material functions to PHAs as well as to study PHA biogenesis via click-chemistry, in which the latter remains unknown and is important for metabolic engineering to produce PHAs economically. PMID:26974339

  16. Influence of morphological parameters on the development of gingival recession in class III malocclusion.

    Science.gov (United States)

    Warmuz, Justyna; Jagielak, Maciej; Botzenhart, Ute; Seeliger, Julia; Gedrange, Tomasz; Dominiak, Marzena

    2016-07-01

    Cephalometric analysis, including both basic cranio- and gnathometric measurements and detailed evaluation of the construction of skeletal, muscular and mucosal systems combined with estimation of the risk of recession's occurrence, can be used to determine the direction of therapy and ensure appropriate aesthetic-functional effects of treatment. The objective of the present study was to compare the influence of the chosen morphologic parameters on the development of gingival recession in the front part of the jaw in patients with Angle class III. The research material was based on the medical documentation of 1800 patients. Sixty generally healthy patients qualified for the research with prognathism. On the basis of the side-head cephalograms, measurements were carried out to describe the bone structure in the front section of the lower jaw. The lower incisor teeth set-up was also analyzed. Gum recession of the lower incisor teeth was assessed on the basis of the inside-mouth photos of the patients with class III malocclusion. The occurrence of recession in a further 4 patients resulted from such a positioning of the lower teeth. In patients in the first group, treated with complex ortho-surgical treatment, the lower incisor teeth were adjusted much more vertically in the alveola and, thus, recession occurred only in one patient. Complex orthodontic-surgical therapy contributes to recession development to a lesser degree than the sham treatment and makes it a safe alternative therapy in patients with high diathesis for occurrence or progression of an existing recession. PMID:26162503

  17. Assessment of temporomandibular disorder and occlusion in treated class III malocclusion patients

    Directory of Open Access Journals (Sweden)

    Karyna Valle-Corotti

    2007-04-01

    Full Text Available OBJECTIVE: The aims of this study were to compare the prevalence of temporomandibular disorders (TMD in individuals submitted to either orthodontic or ortho-surgical Class III malocclusion treatment and to assess the influence of occlusal aspects on TMD severity. MATERIAL AND METHODS: The sample consisted of 50 individuals divided into two groups, according to the type of treatment (orthodontic or orthodontic with orthognathic surgery. The presence of signs and symptoms of TMD was evaluated by an anamnestic questionnaire and a clinical examination, including TMJ and muscle palpation, active mandibular range of motion, joint noises and occlusal examination. RESULTS: Based on the anamnestic questionnaire, 48% had no TMD, 42% had mild TMD and 10% had moderate TMD. The presence and severity of TMD did not show any relationship with the type of orthodontic treatment (p>0.05. The chi-square test showed a positive association (p<0.05 between TMD and non-working side occlusal interferences. CONCLUSION: Based on the methodology used and the results obtained, it may be concluded that Class III orthodontic treatment was not associated with the presence of TMD signs and symptoms and the non-working side contacts can be occlusal factors of risk. There was no significant difference in TMD prevalence between the studied groups (orthodontically treated patients and patients treated with orthodontics followed by orthognathic surgery.

  18. Achados clínicos e polissonográficos em pacientes com obesidade classe III Clinical and polysomnographic findings in class III obese patients

    Directory of Open Access Journals (Sweden)

    Rodrigo de Paiva Tangerina

    2008-08-01

    Full Text Available A Síndrome da apnéia/hipopnéia obstrutiva do sono (SAHOS apresenta estreita correlação com a obesidade, porém não está estabelecida uma relação linear de gravidade principalmente em relação aos extremos como na obesidade mórbida. OBJETIVO: Avaliar os achados clínicos e polissonográficos em pacientes com obesidade classe III e correlacionar esses achados com a presença da SAHOS. MATERIAIS E MÉTODOS: Foram selecionados consecutivamente 45 pacientes com índice de massa corpórea superior a 40Kg/m2. Todos foram submetidos a anamnese, exame físico antropométrico e polissonografia. Os achados foram comparados entre os pacientes com e sem SAHOS. RESULTADOS: 68,9% dos pacientes eram do sexo feminino e 31,1% do masculino. A idade média foi de 46,5 DP 10,8 anos, a média do IMC foi 49 DP 7Kg/m2 e a média da circunferência cervical foi 43,4 DP 5,1cm. Todos os pacientes eram roncadores habituais e 48,9% tinham queixa de hipersonolência diurna. Os achados polissonográficos mostraram que 77,8% apresentaram índice de apnéia/hipopnéia superior a cinco. Apresentaram correlação com a presença da SAHOS: idade mais jovem (p=0,02 e maior circunferência cervical (p=0,004. CONCLUSÃO: A prevalência de SAHOS foi elevada, ressaltando a importância da sua investigação em pacientes referenciados para cirurgia bariátrica. O principal marcador da SAHOS foi a circunferência cervical.The Obstructive Sleep Apnea/Hipopnea Syndrome (OSAHS is closely related to obesity; a linear relation, however, has not been established, particularly in morbid obesity patients. AIM: To evaluate clinical and polysomnographic findings in a group of class III obese patients, and to relate these findings with the presence or absence of OSAHS. MATERIAL AND METHOD: Forty five patients with body mass indexex (BMI over 40Kg/m2 were selected consecutively. A clinical history, the anthropometric examination and polysomnography were undertaken in all patients. The

  19. A roentgenocephalometric study on the condylar displacement in angle's class I and III malocclusion

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jeong Hwa; Park, Chang Seo [Dept. of Oral Radiology, College of Dentistry, Yonsei University, Seoul (Korea, Republic of)

    1986-11-15

    The purpose of this investigation was to know correlation of mean values between centric occlusion and centric relation by the cephalogram in Angle's Class I and III malocclusion subjects. 22 adults with Angle's Class I malocclusion (17 men and 5 women, 21 to 27 years of age) and 14 adult with Angle's class III malocclusion (10 men and 4 women, 21 to 27 years of age) were selected form the dental students in Yonsei University. Each subject was given two lateral cephalometric radiographics and cephalometric analysis was performed. All data form these analyses was recorded and statistically processed with CYBER computer system. The results were obtained as follows: 1. There was a strong positive correlation between centric occlusion and centric relation in all subjects with Angle's Class I and III malocclusion. 2. In Angle's Class I malocclusion, measurements in lower facial height revealed significant difference between centric occlusion and centric relation (p<0.05). 3.When the mandible was movement was 1.27 mm (0.2-2.8 mm) in Angle's Class I malocclusion, 1.70 mm(0.55-4.15 mm) in Angle's Class III malocclusion, and 1.44 mm (0.2- 4.15 mm) in all subjects.

  20. Analysis of variation of sagittal position of the jaw bones in skeletal class III malocclusion

    Directory of Open Access Journals (Sweden)

    Stojanović Zdenka

    2012-01-01

    Full Text Available Background/Aim. Skeletal Class III malocclusion is a discrepancy in the sagittal jaw relationship, due to imbalances in their development and/or position, resulting in the dominant appearance of the lower jaw in facial profile. The aim of this study was to determine variations in the sagittal position of the jaw bones to the cranial base in subjects with skeletal Class III, for the earliest possible diagnosis of malocclusion. Methods. Fifty children and as many adults with skeletal Class III, both sexes, were examined and selected, based on the findings of sagittal interjaw relationship (ANB ≤ 0° from the cephalometric analysis of tele-x-ray profile head shots. The subjects were grouped according to age. The first group consisted of children aged 6-12 years, and another group, of adults aged 18-26 years. We measured the angles of maxillary prognathism (SNA, mandibular prognathism (SNB and ANB. Based on these results, within the respective groups subclassification into the subgroups was done, among which a significant difference measured values was evaluated. In both groups a significant correlation of the determined values was evaluated. Results. An average SNA angle ranged 77.36 ± 3.58 in children and 77.32 ± 4.88 in adults, while an average SNB angle was 79.46 ± 3.91 in the group of children and 81.12 ± 3.76 in adults. An average ANB angle was -2.10 ± 2.07 in children, and -4.00 ± 2.34 in adults. In both groups, a significant correlation between the measured values and a significant difference in the values of all the measured parameters were found between patients from different subgroups (p < 0.01. Conclusion. The most common morphological variation of sagittal position of the upper jaw is its retrognatism, which is equally present in both children and adults. Sagittal position of the lower jaw in most of the adults was prognathic, while mandible prognathism in the children was less present.

  1. Treatment of Class III malocclusion in a young adult patient: a case report.

    Science.gov (United States)

    Kiran, B H Jyothi; Kumar, Prashanth; Ravi, S; Shivalinga, B M; Bhagyalaxmi; Pradeep; Kudagi, Vishal

    2012-01-01

    This article describes the treatment of a young adult male with a concave profile, skeletal class III malocclusion because of a prognathic mandible and proclined upper incisors. The therapy included stages: 1. Pre-surgical orthodontics involving leveling and aligning of upper and lower arches, protraction of lower molars and retraction of upper incisors; 2. Surgical phase involving BSSO with mandibular setback and 3. Post-surgical orthodontics for finishing and detailing. The treatment lasted 23 months and improved facial esthetics significantly The treatment resulted in a functional occlusion with a lack of lateral cuspid guidance that could be accepted considering the difficulty of the case. Over jet and overbite are within norms. PMID:23094557

  2. Prosthetic rehabilitation of severe Siebert′s Class III defect with modified Andrews bridge system

    Directory of Open Access Journals (Sweden)

    Manu Rathee

    2015-01-01

    Full Text Available Prosthetic dentistry involves the replacement of missing and contiguous tissues with artificial substitutes to restore and maintain the oral functions, appearance, and health of the patient. The treatment of edentulous areas with ridge defects poses a challenging task for the dentist. Management of such cases involves a wide range of treatment options comprising mainly of surgical interventions and non surgical techniques such as use of removable, fixed or fixed- removable partial dentures. But each treatment plan undertaken should be customized according to patient needs. A variety of factors such as quality and quantity of existing contiguous hard and soft tissues, systemic condition and economic status of the patient play an important role in treatment planning, clinical outcome and prognosis. This case report presents the restoration of a Seibert′s Class III ridge defect by an economical modification of Andrews Bridge in a 32 Year old patient.

  3. Prosthetic rehabilitation of severe Siebert's Class III defect with modified Andrews bridge system.

    Science.gov (United States)

    Rathee, Manu; Sikka, Neha; Jindal, Sahil; Kaushik, Ashutosh

    2015-03-01

    Prosthetic dentistry involves the replacement of missing and contiguous tissues with artificial substitutes to restore and maintain the oral functions, appearance, and health of the patient. The treatment of edentulous areas with ridge defects poses a challenging task for the dentist. Management of such cases involves a wide range of treatment options comprising mainly of surgical interventions and non surgical techniques such as use of removable, fixed or fixed- removable partial dentures. But each treatment plan undertaken should be customized according to patient needs. A variety of factors such as quality and quantity of existing contiguous hard and soft tissues, systemic condition and economic status of the patient play an important role in treatment planning, clinical outcome and prognosis. This case report presents the restoration of a Seibert's Class III ridge defect by an economical modification of Andrews Bridge in a 32 Year old patient. PMID:25821362

  4. Complex networks for data-driven medicine: the case of Class III dentoskeletal disharmony

    International Nuclear Information System (INIS)

    In the last decade, the availability of innovative algorithms derived from complexity theory has inspired the development of highly detailed models in various fields, including physics, biology, ecology, economy, and medicine. Due to the availability of novel and ever more sophisticated diagnostic procedures, all biomedical disciplines face the problem of using the increasing amount of information concerning each patient to improve diagnosis and prevention. In particular, in the discipline of orthodontics the current diagnostic approach based on clinical and radiographic data is problematic due to the complexity of craniofacial features and to the numerous interacting co-dependent skeletal and dentoalveolar components. In this study, we demonstrate the capability of computational methods such as network analysis and module detection to extract organizing principles in 70 patients with excessive mandibular skeletal protrusion with underbite, a condition known in orthodontics as Class III malocclusion. Our results could possibly constitute a template framework for organising the increasing amount of medical data available for patients’ diagnosis. (paper)

  5. Shoot meristem function and leaf polarity: the role of class III HD-ZIP genes.

    Directory of Open Access Journals (Sweden)

    Mary E Byrne

    2006-06-01

    Full Text Available The shoot apical meristem comprises an organized cluster of cells with a central region population of self-maintaining stem cells providing peripheral region cells that are recruited to form differentiated lateral organs. Leaves, the principal lateral organ of the shoot, develop as polar structures typically with distinct dorsoventrality. Interdependent interactions between the meristem and developing leaf provide essential cues that serve both to maintain the meristem and to pattern dorsoventrality in the initiating leaf. A key component of both processes are the class III HD-ZIP genes. Current findings are defining the developmental role of members of this family and are identifying multiple mechanisms controlling expression of these genes.

  6. Minimal presurgical orthodontics for a skeletal Class III patient with mandibular asymmetry.

    Science.gov (United States)

    Zhou, Yang; Zhou, Yanheng; Wang, Xiaoxia; Li, Zili

    2016-01-01

    A 19-year-old man with a skeletal Class III malocclusion was treated using minimal presurgical orthodontics. Orthodontic appliances and miniscrews were placed at the beginning of treatment, and the double-jaw-surgery was performed once the maxillary right and left first premolars were intruded, without worsening the concave profile and facial asymmetry presurgically. Different from the traditional combined orthodontic-orthognathic surgery, the jaw discrepancy was corrected first, followed by the orthodontic tooth movement. Miniscrews were used to intrude the premolars presurgically because of their interference and to provide the skeletal anchorage for intermaxillary elastics after the operation. The patient was pleased with the treatment results and satisfied with his facial and dental appearance, as well as his oral function. The 1-year follow-up photographs show a stable result both esthetically and functionally. PMID:26718384

  7. Segmental LeFort I osteotomy for treatment of a class III malocclusion with temporomandibular disorder

    Directory of Open Access Journals (Sweden)

    Marcos Janson

    2008-08-01

    Full Text Available This article reports the case of a 19-year-old young man with Class III malocclusion and posterior crossbite with concerns about temporomandibular disorder (TMD, esthetics and functional problems. Surgical-orthodontic treatment was carried out by decompensation of the mandibular incisors and segmentation of the maxilla in 4 pieces, which allowed expansion and advancement. Remission of the signs and symptoms occurred after surgical-orthodontic intervention. The maxillary dental arch presented normal transverse dimension. Satisfactory static and functional occlusion and esthetic results were achieved and remained stable. Three years after the surgical-orthodontic treatment, no TMD sign or symptom was observed and the occlusal results had not changed. When vertical or horizontal movements of the maxilla in the presence of moderate maxillary constriction are necessary, segmental LeFort I osteotomy can be an important part of treatment planning.

  8. Structural diversity and transcription of class III peroxidases from Arabidopsis thaliana.

    Science.gov (United States)

    Welinder, Karen G; Justesen, Annemarie F; Kjaersgård, Inger V H; Jensen, Rikke B; Rasmussen, Søren K; Jespersen, Hans M; Duroux, Laurent

    2002-12-01

    Understanding peroxidase function in plants is complicated by the lack of substrate specificity, the high number of genes, their diversity in structure and our limited knowledge of peroxidase gene transcription and translation. In the present study we sequenced expressed sequence tags (ESTs) encoding novel heme-containing class III peroxidases from Arabidopsis thaliana and annotated 73 full-length genes identified in the genome. In total, transcripts of 58 of these genes have now been observed. The expression of individual peroxidase genes was assessed in organ-specific EST libraries and compared to the expression of 33 peroxidase genes which we analyzed in whole plants 3, 6, 15, 35 and 59 days after sowing. Expression was assessed in root, rosette leaf, stem, cauline leaf, flower bud and cell culture tissues using the gene-specific and highly sensitive reverse transcriptase-polymerase chain reaction (RT-PCR). We predicted that 71 genes could yield stable proteins folded similarly to horseradish peroxidase (HRP). The putative mature peroxidases derived from these genes showed 28-94% amino acid sequence identity and were all targeted to the endoplasmic reticulum by N-terminal signal peptides. In 20 peroxidases these signal peptides were followed by various N-terminal extensions of unknown function which are not present in HRP. Ten peroxidases showed a C-terminal extension indicating vacuolar targeting. We found that the majority of peroxidase genes were expressed in root. In total, class III peroxidases accounted for an impressive 2.2% of root ESTs. Rather few peroxidases showed organ specificity. Most importantly, genes expressed constitutively in all organs and genes with a preference for root represented structurally diverse peroxidases (< 70% sequence identity). Furthermore, genes appearing in tandem showed distinct expression profiles. The alignment of 73 Arabidopsis peroxidase sequences provides an easy access to the identification of orthologous peroxidases

  9. S-Nitrosoglutathione is a substrate for rat alcohol dehydrogenase class III isoenzyme.

    Science.gov (United States)

    Jensen, D E; Belka, G K; Du Bois, G C

    1998-04-15

    An enzyme isolated from rat liver cytosol (native molecular mass 78. 3 kDa; polypeptide molecular mass 42.5 kDa) is capable of catalysing the NADH/NADPH-dependent degradation of S-nitrosoglutathione (GSNO). The activity utilizes 1 mol of coenzyme per mol of GSNO processed. The isolated enzyme has, as well, several characteristics that are unique to alcohol dehydrogenase (ADH) class III isoenzyme: it is capable of catalysing the NAD+-dependent oxidations of octanol (insensitive to inhibition by 4-methylpyrazole), methylcrotyl alcohol (stimulated by added pentanoate) and 12-hydroxydodecanoic acid, and also the NADH/NADPH-dependent reduction of octanal. Methanol and ethanol oxidation activity is minimal. The enzyme has formaldehyde dehydrogenase activity in that it is capable of catalysing the NAD+/NADP+-dependent oxidation of S-hydroxymethylglutathione. Treatment with the arginine-specific reagent phenylglyoxal prevents the pentanoate stimulation of methylcrotyl alcohol oxidation and markedly diminishes the enzymic activity towards octanol, 12-hydroxydodecanoic acid and S-hydroxymethylglutathione; the capacity to catalyse GSNO degradation is also checked. Additionally, limited peptide sequencing indicates 100% correspondence with known ADH class III isoenzyme sequences. Kinetic studies demonstrate that GSNO is an exceptionally active substrate for this enzyme. S-Nitroso-N-acetylpenicillamine and S-nitrosated human serum albumin are not substrates; the activity towards S-nitrosated glutathione mono- and di-ethyl esters is minimal. Product analysis suggests that glutathione sulphinamide is the major stable product of enzymic GSNO processing, with minor yields of GSSG and NH3; GSH, hydroxylamine, nitrite, nitrate and nitric oxide accumulations are minimal. Inclusion of GSH in the reaction mix decreases the yield of the supposed glutathione sulphinamide in favor of GSSG and hydroxylamine. PMID:9531510

  10. An innovative approach for correction of pseudo class III malocclusion with the use of "Planas direct tracks"

    Directory of Open Access Journals (Sweden)

    Ketan Sukumar Vora

    2013-01-01

    Full Text Available Anterior cross bite due to a pseudo Class III is a kind of malocclusion, which has a potential to turn into a facial deformity. This orthodontic emergency should be treated as soon as it is observed. A case of pseudo Class III was treated with Planas direct tracks (PDT. The PDT was designed such that the distal incline of the upper block occludes with mesial incline of the lower block such that the mandible will have a posterior path of closure with condyles in centric relation. Significant clinical change was seen in the subject. There was a significant reduction in mesial step and a considerable improvement in the facial profile. Cephalometrically, there was a significant increase seen in the lower anterior facial height. PDT is an efficient solution for the correction of early pseudo Class III malocclusion.

  11. The Quantum Mixed-Spin Heme State of Barley Peroxidase: A Paradigm for Class III Peroxidases

    Energy Technology Data Exchange (ETDEWEB)

    Howes, B.D.; Ma, J.; Marzocchi, M.P.; Schiodt, C.B.; Shelnutt, J.A.; Smulevich, G.; Welinder, K.G.; Zhang, J.

    1999-03-23

    Electronic absorption and resonance Raman (RR) spectra of the ferric form of barley grain peroxidase (BP 1) at various pH values both at room temperature and 20 K are . reported, together with EPR spectra at 10 K. The ferrous forms and the ferric complex with fluoride have also been studied. A quantum mechanically mixed-spin (QS) state has been identified. The QS heme species co-exists with 6- and 5-cHS heroes; the relative populations of these three spin states are found to be dependent on pH and temperature. However, the QS species remains in all cases the dominant heme spin species. Barley peroxidase appears to be further characterized by a splitting of the two vinyl stretching modes, indicating that the vinyl groups are differently conjugated with the porphyrin. An analysis of the presently available spectroscopic data for proteins from all three peroxidase classes suggests that the simultaneous occurrence of the QS heme state as well as the splitting of the two vinyl stretching modes is confined to class III enzymes. The former point is discussed in terms of the possible influences of heme deformations on heme spin state. It is found that moderate saddling alone is probably not enough to cause the QS state, although some saddling maybe necessary for the QS state.

  12. Long maximal incremental tests accurately assess aerobic fitness in class II and III obese men.

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    Stefano Lanzi

    Full Text Available This study aimed to compare two different maximal incremental tests with different time durations [a maximal incremental ramp test with a short time duration (8-12 min (STest and a maximal incremental test with a longer time duration (20-25 min (LTest] to investigate whether an LTest accurately assesses aerobic fitness in class II and III obese men. Twenty obese men (BMI≥35 kg.m-2 without secondary pathologies (mean±SE; 36.7±1.9 yr; 41.8±0.7 kg*m-2 completed an STest (warm-up: 40 W; increment: 20 W*min-1 and an LTest [warm-up: 20% of the peak power output (PPO reached during the STest; increment: 10% PPO every 5 min until 70% PPO was reached or until the respiratory exchange ratio reached 1.0, followed by 15 W.min-1 until exhaustion] on a cycle-ergometer to assess the peak oxygen uptake [Formula: see text] and peak heart rate (HRpeak of each test. There were no significant differences in [Formula: see text] (STest: 3.1±0.1 L*min-1; LTest: 3.0±0.1 L*min-1 and HRpeak (STest: 174±4 bpm; LTest: 173±4 bpm between the two tests. Bland-Altman plot analyses showed good agreement and Pearson product-moment and intra-class correlation coefficients showed a strong correlation between [Formula: see text] (r=0.81 for both; p≤0.001 and HRpeak (r=0.95 for both; p≤0.001 during both tests. [Formula: see text] and HRpeak assessments were not compromised by test duration in class II and III obese men. Therefore, we suggest that the LTest is a feasible test that accurately assesses aerobic fitness and may allow for the exercise intensity prescription and individualization that will lead to improved therapeutic approaches in treating obesity and severe obesity.

  13. Morphology of the temporomandibular joint in skeletal class iii symmetrical and asymmetrical cases: a study by cephalometric laminography.

    Science.gov (United States)

    Akahane, Y; Deguchi, T; Hunt, N P

    2001-06-01

    The aetiology of asymmetric growth in the mandible is not well understood. Previous studies have indicated that the functional lateral shift of the mandible in the period of prepubertal growth may translate to a true skeletal asymmetry, exclusively in skeletal Class III malocclusion. This asymmetry develops more characteristic features during the pubertal and post-pubertal growth periods. Early correction of a functional lateral shift of the mandible is recommended. The purpose of this study was to examine the relationship between the morphology of the temporomandibular joints and asymmetry in skeletal Class III malocclusion in adult female patients. Cephalometric and laminographic findings in 36 asymmetric skeletal Class III patients with a lateral shift of mandible (group 3) were compared to those of 25 symmetric skeletal Class I patients (group 1) and the same number of symmetric skeletal Class III malocclusions (group 2). All the patients had received no orthodontic treatment. The results showed that the TMJ of the side to which the mandible shifted showed a significantly narrower and shorter shape of the condyle head, smaller superior condylar space, and steeper eminence than those of the unshifted side. PMID:11395526

  14. Miniscrew-assisted mandibular molar distalization in a patient with skeletal class-III malocclusion: A clinical case report

    Directory of Open Access Journals (Sweden)

    Seyed Mohammadreza Safavi

    2013-01-01

    Full Text Available In nongrowing patients with mild skeletal Class-III malocclusion, premolar extraction or molar distalization in the lower arch can be done as a part of camouflage treatment. Temporary anchorage devices are widely used for this purpose because they do not produce undesirable reciprocal effects and do not depend on the patient′s cooperation. However, most reported cases in this regard have used interradicular miniscrews in the mandibular arch and these have a risk of failure as they can loosen due to collision with adjacent roots. This article showcases mandibular molar distalization utilizing miniscrews, inserted at the retromolar area to correct a Class-III problem. A 24-year-old girl with a mild skeletal Class-III malocclusion and dental Class-III molar and canine relationship bilaterally was referred for orthodontic treatment. The treatment plan included distalization of the lower molars bilaterally followed by full fixed appliance therapy, after third molar extractions. For the lower molar distalization, the miniscrews were inserted at the retromolar pad. At the end of 21 months, a Class-I molar and canine relationship, normal overjet and overbite were obtained. The average amount of distalization of mandibular first molar was 3.2 mm at the crown level. In conclusion, placing miniscrews at the retromolar pad area for lower molar distalization was found to be a simple and effective method for correcting anterior cross bite and mandibular anterior crowding or protrusion, without the need for patient compliance.

  15. Cirurgia ortognática: abordagem psicossocial em pacientes Classe III de Angle submetidos à correção cirúrgica da deformidade dentofacial Orthognathic surgery: psychosocial approach in Angle Class III patients submitted to correction surgery of facial deformity

    Directory of Open Access Journals (Sweden)

    Denise Nicodemo

    2007-10-01

    Full Text Available OBJETIVO: investigar aspectos psicossociais relacionados à mudança da aparência facial em 29 pacientes, de ambos os gêneros, com idades entre 17 e 46 anos, com indicação de tratamento cirúrgico, nos períodos pré-operatório (durante preparo ortodôntico e pós-operatório (transcorridos 6 meses da intervenção cirúrgica. MÉTODOS: utilizou-se questionários, aplicados na forma de entrevistas, com perguntas baseadas na proposta de Grossbart e Sarwer. Utilizou-se a técnica de análise de conteúdo, representando-se o motivo da procura pela correção cirúrgica em Categoria 1 (C1; as fantasias relacionadas aos resultados da correção cirúrgica (pré-operatório e realização (pós-operatório em Categoria 2 (C2; e as expectativas e a satisfação quanto aos resultados da correção cirúrgica em Categoria 3 (C3. As respostas foram reagrupadas nas subcategorias: estética (SC1, funcional (SC2, situações sociais (SC3, auto-estima (SC4 e profissional (SC5. RESULTADOS: os resultados indicaram que os pacientes procuraram a correção cirúrgica por motivos funcionais (34,5%, estéticos (30,9% e sociais (29,1%; desejavam melhorar as situações sociais (40% e a estética (32%, com realização destes desejos, depois da cirurgia. Quanto às expectativas, 49,4% dos pacientes esperavam melhorar o aspecto funcional, seguido da estética (26,9%, situações sociais (11,2% e auto-estima (6,7%. Em todos os aspectos, os pacientes ficaram muito satisfeitos pela melhora na dicção, na estética, na beleza e no retorno à vida sem discriminação. CONCLUSÕES: os pacientes procuraram a correção cirúrgica motivados a melhorar o aspecto funcional e a estética; fantasiavam melhorar as relações sociais e a aparência; esperavam, de forma realista, que a correção cirúrgica reparasse a função e a estética - objetivos propostos pela cirurgia ortognática.AIM: The purpose of this work was to investigate the psychosocial aspects related to facial changes in 29 patients, from both genres, between 17 and 46 years old, with indication of surgical treatment, in the preoperative (during orthodontic preparation and in the postoperative (six months after the surgery periods. METHODS: Questionnaires, applied during interviews, with questions based on the proposal by Grossbart & Sarwer were used. The technique of content analysis was used, in which the reason for choosing corrective surgery were represented in Category 1 (C1; fantasies related to the results of the corrective surgery (preoperative and performance (postoperative in Category 2 (C2; and expectations and satisfaction of the results of the corrective surgery in Category 3 (C3. The answers were grouped in the subcategories: aesthetics (SC1, functional (SC2, social situations (SC3, self-esteem (SC4 and professional (SC5. RESULTS: the results showed that the patients looked for corrective surgery for functional reasons (34.5%, aesthetics (30.9% and social (29.1%; wished to improve his/her social situation (40% and the aesthetics (32%, with the fulfillment of these wishes after the surgery. As for the expectations, 49.4% of the patients hoped to improve the functional aspect followed by aesthetics (26.9%; social situations (11.2% and self-esteem (6.7%. In all aspects the patients were very satisfied because of improvements in their diction, aesthetics, beauty, and the return to life without discrimination. CONCLUSIONS: It can be concluded that the patients looked for the corrective surgery with the motivation to improve their functional and aesthetics aspects, they fantasized to improve their social relations and appearance; and hoped, in a realistic way, that the corrective surgery would repaired the function and aesthetics - which are the objectives of the orthognathic surgery.

  16. Self-esteem in adolescents with Angle Class I, II and III malocclusion in a Peruvian sample

    Science.gov (United States)

    Florián-Vargas, Karla; Honores, Marcos J. Carruitero; Bernabé, Eduardo; Flores-Mir, Carlos

    2016-01-01

    ABSTRACT Objective: To compare self-esteem scores in 12 to 16-year-old adolescents with different Angle malocclusion types in a Peruvian sample. Material and Methods: A cross-sectional study was conducted in a sample of 276 adolescents (159, 52 and 65 with Angle Class I, II and III malocclusions, respectively) from Trujillo, Peru. Participants were asked to complete the Rosenberg Self-Esteem Scale (RSES) and were also clinically examined, so as to have Angle malocclusion classification determined. Analysis of covariance (ANCOVA) was used to compare RSES scores among adolescents with Class I, II and III malocclusions, with participants' demographic factors being controlled. Results: Mean RSES scores for adolescents with Class I, II and III malocclusions were 20.47 ± 3.96, 21.96 ± 3.27 and 21.26 ± 4.81, respectively. The ANCOVA test showed that adolescents with Class II malocclusion had a significantly higher RSES score than those with Class I malocclusion, but there were no differences between other malocclusion groups. Supplemental analysis suggested that only those with Class II, Division 2 malocclusion might have greater self-esteem when compared to adolescents with Class I malocclusion. Conclusion: This study shows that, in general, self-esteem did not vary according to adolescents' malocclusion in the sample studied. Surprisingly, only adolescents with Class II malocclusion, particularly Class II, Division 2, reported better self-esteem than those with Class I malocclusion. A more detailed analysis assessing the impact of anterior occlusal features should be conducted. PMID:27275616

  17. Self-esteem in adolescents with Angle Class I, II and III malocclusion in a Peruvian sample

    Directory of Open Access Journals (Sweden)

    Karla Florián-Vargas

    2016-04-01

    Full Text Available ABSTRACT Objective: To compare self-esteem scores in 12 to 16-year-old adolescents with different Angle malocclusion types in a Peruvian sample. Material and Methods: A cross-sectional study was conducted in a sample of 276 adolescents (159, 52 and 65 with Angle Class I, II and III malocclusions, respectively from Trujillo, Peru. Participants were asked to complete the Rosenberg Self-Esteem Scale (RSES and were also clinically examined, so as to have Angle malocclusion classification determined. Analysis of covariance (ANCOVA was used to compare RSES scores among adolescents with Class I, II and III malocclusions, with participants' demographic factors being controlled. Results: Mean RSES scores for adolescents with Class I, II and III malocclusions were 20.47 ± 3.96, 21.96 ± 3.27 and 21.26 ± 4.81, respectively. The ANCOVA test showed that adolescents with Class II malocclusion had a significantly higher RSES score than those with Class I malocclusion, but there were no differences between other malocclusion groups. Supplemental analysis suggested that only those with Class II, Division 2 malocclusion might have greater self-esteem when compared to adolescents with Class I malocclusion. Conclusion: This study shows that, in general, self-esteem did not vary according to adolescents' malocclusion in the sample studied. Surprisingly, only adolescents with Class II malocclusion, particularly Class II, Division 2, reported better self-esteem than those with Class I malocclusion. A more detailed analysis assessing the impact of anterior occlusal features should be conducted.

  18. Radiographic cephalometry assessment of the linear and angular parameters on cranial base in children with skeletal class III

    Directory of Open Access Journals (Sweden)

    Stojanović Zdenka M.

    2007-01-01

    Full Text Available Background/Aim. In malocclusion of skeletal class III, mandible is located in front of maxilla in sagital plain, which is manifested by a lower value of the sagital inter-jaw angle than in skeletal class I, where the jaw sagital relation is normal. Apart from the deformities on mandible and/or maxilla, in skeletal class III deformities are also frequent on the cranial base. The aim of this research was to find the differences in the parameter values on the cranial base among the children with skeletal class III and the children with skeletal class I in the period of mixed dentition. Methods. After clinical examination and orthopan-tomography, profile radiography of the head was analyzed in 60 examinees, aged from 6−12 years. The examinees were divided into two groups: group 1 - the children with skeletal class III; group 2 - the children with skeletal class I. Both linear and angular parameters on the cranial base were measured, as well as the angles of maxillary and mandible prognatism and the angle of sagital inter-jaw relation. The level of difference in the parameter values between the groups was estimated and the degree of correlation of the main angle of the cranial base with the angles of sagital position of the jaws in each of the two groups was established. Results. A significant difference between the groups was found only in the average values of the angles of maxillary prognatism and sagital interjaw relation. In the group 1, the main angle of the cranial base was in a significant correlation with the angles of sagital positions of the jaws, while in the group 2, such significance was not found. Conclusion. There were no significant differences in the parameter values on the cranial base between the groups. There was a significant correlation of the main angle of the cranial base with the angles of sagital position of the jaws in the group 1 only. .

  19. Class III β-tubulin in advanced NSCLC of adenocarcinoma subtype predicts superior outcome in a randomized trial

    DEFF Research Database (Denmark)

    Vilmar, Adam Christian; Santoni-Rugiu, Eric; Sørensen, Jens Benn

    2011-01-01

    Platinum-based doublets are the cornerstone of treatment in advanced non-small-cell lung cancer (NSCLC) and often include vinorelbine or taxanes. A predictive biomarker is greatly needed to select chemotherapy-sensitive patients for these microtubule-interfering agents. Class III β-tubulin (TUBB3...

  20. 40 CFR 147.2400 - State-administered program-Class I, II, III, IV, and V wells.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false State-administered program-Class I, II, III, IV, and V wells. 147.2400 Section 147.2400 Protection of Environment ENVIRONMENTAL PROTECTION... between the Washington Department of Ecology and Department of Social and Health Services, Related to...

  1. Proteomics computational analyses suggest that the bornavirus glycoprotein is a class III viral fusion protein (γ penetrene

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    Garry Robert F

    2009-09-01

    Full Text Available Abstract Background Borna disease virus (BDV is the type member of the Bornaviridae, a family of viruses that induce often fatal neurological diseases in horses, sheep and other animals, and have been proposed to have roles in certain psychiatric diseases of humans. The BDV glycoprotein (G is an extensively glycosylated protein that migrates with an apparent molecular mass of 84,000 to 94,000 kilodaltons (kDa. BDV G is post-translationally cleaved by the cellular subtilisin-like protease furin into two subunits, a 41 kDa amino terminal protein GP1 and a 43 kDa carboxyl terminal protein GP2. Results Class III viral fusion proteins (VFP encoded by members of the Rhabdoviridae, Herpesviridae and Baculoviridae have an internal fusion domain comprised of beta sheets, other beta sheet domains, an extended alpha helical domain, a membrane proximal stem domain and a carboxyl terminal anchor. Proteomics computational analyses suggest that the structural/functional motifs that characterize class III VFP are located collinearly in BDV G. Structural models were established for BDV G based on the post-fusion structure of a prototypic class III VFP, vesicular stomatitis virus glycoprotein (VSV G. Conclusion These results suggest that G encoded by members of the Bornavirdae are class III VFPs (gamma-penetrenes.

  2. A Morphological Study on the Relationship between Arch Form and Craniofacial Structures in Skeletal Class I and Class III Japanese Patient

    OpenAIRE

    NARUZAWA, ROBERTA MIYOE; MINOSHIMA, YASUHIRO; KAGEYAMA, TORU; Deguchi, Toshio; KURIHARA, SABURO

    1999-01-01

    Available studies about differences among races, related to prevalence of malocclusion or morphology of head and dental arches, suggest a hypothesis that the high prevalence of skeletal Class III malocclusion in Asian ancestry populations could be correlated with a tendency toward a brachycephalic head form and larger arches widths. The purpose of the present study was to evaluate anteroposterior relationship of upper and lower jaws associated to form of dental arches, maxilla, mandible, face...

  3. Impact of physical activity and fitness in class II and III obese individuals: a systematic review.

    Science.gov (United States)

    Baillot, A; Audet, M; Baillargeon, J P; Dionne, I J; Valiquette, L; Rosa-Fortin, M M; Abou Chakra, C N; Comeau, E; Langlois, M F

    2014-09-01

    The objective of this systematic review was to appraise current knowledge on the impact of physical activity (PA) and physical fitness (PF) on the health of class II and III obese subjects and bariatric surgery (BS) patients. All original studies were searched using four databases (Medline®, Scopus®, CINAHL and Sportdiscus). Two independent investigators selected studies assessing the impact of PA or PF on specific health outcomes (anthropometric parameters, body composition, cardiometabolic risk factors, PF, wellness) in adults with a body mass index ≥35 kg m(-2) or in BS patients. Conclusions were drawn based on a rating system of evidence. From 3,170 papers identified, 40 papers met the inclusion criteria. The vast majority of studies were recently carried out with a predominance of women. Less than one-third of these studies were experimental and only three of them were of high quality. Each study reported at least one beneficial effect of PA or PF. However, a lack of high-quality studies and heterogeneity in designs prevented us from finding high levels of evidence. In conclusion, although results support the importance of PA and PF to improve the health of this population, higher-quality trials are required to strengthen evidence-based recommendations. PMID:24712685

  4. [Limiting factors in the class III camouflage treatment: a potential protocol].

    Science.gov (United States)

    Chaques Asensi, José

    2016-06-01

    The Class III skeletal malocclusion has been traditionally treated with a combined approach of orthodontics and orthognathic surgery or with a strategy of orthodontic camouflage. Some severe cases can be identified as ideal candidates for a surgical treatment whereas some others can be handled with orthodontics alone, with a reasonable expectation of an acceptable result. However, the problem remains for the borderline patient. In fact, limited information is available in the literature regarding the identification of the factors that can help in establishing the limits for one treatment modality or the other. Furthermore, the quantification of some of these factors, for practical purposes, is practically missing or very seldom suggested. Therefore, the decision making process remains a subjective reflection based on the "good clinical sense" of the orthodontist or just reduced to an "educated guess". In order to add some information, hopefully useful in deciding the most suitable treatment option for the individual patient, we propose a clinical protocol based on four different factors. Namely: the skeletal discrepancy, the occlusal discrepancy, the periodontal condition and facial aesthetics. For each one of these factors several parameters will be evaluated and, for some of them, an attempt to provide some reference numerical values will be made. Finally, clinical examples will be presented to illustrate the concepts discussed and the treatment alternatives, final treatment plan and treatment outcome will be analyzed for each one of them. PMID:27358006

  5. A vacuolar class III peroxidase and the metabolism of anticancer indole alkaloids in Catharanthus roseus

    Science.gov (United States)

    Duarte, Patrícia; Figueiredo, Raquel; Ros Barceló, Alfonso

    2008-01-01

    Plants possess a unique metabolic diversity commonly designated as secondary metabolism, of which the anticancer alkaloids from Catharanthus roseus are among the most studied. Recently, in a classical function-to-protein-to-gene approach, we have characterized the main class III peroxidase (Prx) expressed in C. roseus leaves, CrPrx1, implicated in a key biosynthetic step of the anticancer alkaloids. We have shown the vacuolar sorting determination of CrPrx1 using GFP fusions and we have obtained further evidence supporting the role of this enzyme in alkaloid biosynthesis, indicating the potential of CrPrx1 as a molecular tool for the manipulation of alkaloid metabolism. Here, we discuss how plant cells may regulate Prx reactions. In fact, Prxs form a large multigenic family whose members accept a broad range of substrates and, in their two subcellular localizations, the cell wall and the vacuole, Prxs co-locate with a large variety of secondary metabolites which can be accepted as substrates. How then, are Prx reactions regulated? Localization data obtained in our lab suggest that arabinogalactan proteins (AGPs) and Prxs may be associated in membrane microdomains, evocative of lipid rafts. Whether plasma membrane and/or tonoplast microcompartmentation involve AGPs and Prxs and whether this enables metabolic channeling determining Prx substrate selection are challenging questions ahead. PMID:19704535

  6. Cephalometric evaluation of class-III patients with chin cap and tongue guard

    Directory of Open Access Journals (Sweden)

    Danaie S

    2005-06-01

    Full Text Available The purpose of this study was to determine the effect of chin cap therapy combined with an upper tongue guard in the early treatment of class-III malocclusion on the nasomaxillary complex and mandible. The subjects of this study consisted of 40 patients aged 5-13 years (mean age of 8.5 ± 2. All of them possessed an anterior cross bite and/or concave profile. The mean force of chin cap was determined to be 200 g on each side for 18 h/day and the mean treatment period was 22 months. The cephalometric analyses including skeletal, dental, and soft tissue analysis were carried out before and after treatment. The analysis of the cephalometric measurements revealed a negative correlation between the combination effects of chin cap therapy upper tongue guard. This effect appeared in the early stages of treatment. It was a case-control study and Wilcoxon test was used for statistical analysis. The comparison of dependent variables revealed that skeletal effects of chin cap therapy were more than dental and soft tissue effects. Changes in the upper and lower pharyngeal spaces were not significant. A reduction of nasolabial angle occurred due to the protrusion of upper incisors. Finally, it was shown that the combination of chin cap and upper tongue guard could be more effective in the early treatment.

  7. South European Journal of Orthodontics and Dentofacial Research: A new hope

    OpenAIRE

    Lauc, Tomislav

    2014-01-01

    Welcome to South European Journal of Orthodontics and Dentofacial Research. Today, orthodontics is different. In the last twenty years technology has posed new challenges not only for orthodontics but for all fields of dental medicine, and science in general. Technological progress is also creating new opportunities in research with new study designs and new questions, opening space for re-evaluating present paradigms and creating new ideas in perceiving basics of orthodontic, pedodontic ...

  8. Asymmetric molar distalization with miniscrews to correct a severe unilateral Class III malocclusion.

    Science.gov (United States)

    Ma, Qiao Ling; Conley, R Scott; Wu, Tuojiang; Li, Huang

    2016-05-01

    Asymmetries are among the most challenging problems in orthodontics. Proper diagnosis is critical to discern first whether the asymmetry is dental or skeletal. If it is dental, one must then determine whether one dental arch or both are at fault. Once diagnosed, the next challenge is determining not only an appropriate treatment plan, but also the appropriate mechanics plan. This aim of this article is to present a patient with a severe asymmetry to emphasize the importance of a problem-based differential diagnosis to develop both a sound treatment plan and a mechanics plan that successfully integrates miniscrews from the start of the process. An 18-year-old woman had a Class III subdivision left malocclusion, an asymmetric lower facial third, and a deviated midline. The treatment plan consisted of asymmetric distalization of the maxillary right and mandibular left posterior dentitions to create space to resolve the deviated midlines, correct the canted occlusal plane, and obtain an ideal occlusion. Active treatment with Clarity ceramic 0.022 × 0.028-in appliances (3M Unitek, Monrovia, Calif), temporary anchorage devices, and a pendulum appliance lasted 22 months. The final result and the 2-year retention records demonstrate that a harmonious facial balance, an attractive smile, ideal occlusal relationships, and a stable outcome were achieved. This case report shows that with proper planning, asymmetric use of temporary anchorage devices in multiple posterior quadrants can be used to obtain molar distalization, and this approach is an effective alternative to dental extraction therapy. PMID:27131255

  9. Molecular characterization of fruit-specific class III peroxidase genes in tomato (Solanum lycopersicum).

    Science.gov (United States)

    Wang, Chii-Jeng; Chan, Yuan-Li; Shien, Chin Hui; Yeh, Kai-Wun

    2015-04-01

    In this study, expression of four peroxidase genes, LePrx09, LePrx17, LePrx35 and LePrxA, was identified in immature tomato fruits, and the function in the regulation of fruit growth was characterized. Analysis of amino acid sequences revealed that these genes code for class III peroxidases, containing B, D and F conserved domains, which bind heme groups, and a buried salt bridge motif. LePrx35 and LePrxA were identified as novel peroxidase genes in Solanum lycopersicum (L.). The temporal expression patterns at various fruit growth stages revealed that LePrx35 and LePrxA were expressed only in immature green (IMG) fruits, whereas LePrx17 and LePrx09 were expressed in both immature and mature green fruits. Tissue-specific expression profiles indicated that only LePrx09 was expressed in the mesocarp but not the inner tissue of immature fruits. The effects of hormone treatments and stresses on the four genes were examined; only the expression levels of LePrx17 and LePrx09 were altered. Transcription of LePrx17 was up-regulated by jasmonic acid (JA) and pathogen infection and expression of LePrx09 was induced by ethephon, salicylic acid (SA) and JA, in particular, as well as wounding, pathogen infection and H2O2 stress. Tomato plants over-expressing LePrx09 displayed enhanced resistance to H2O2 stress, suggesting that LePrx09 may participate in the H2O2 signaling pathway to regulate fruit growth and disease resistance in tomato fruits. PMID:25703772

  10. Purification, crystallization and preliminary X-ray diffraction analysis of a class P-III metalloproteinase (BmMP-III) from the venom of Bothrops moojeni

    International Nuclear Information System (INIS)

    The P-III metalloproteinase from B. moojeni was crystallized and diffraction data were collected to a maximum resolution of 3.3 Å. Snake-venom metalloproteinases (SVMPs) comprise a family of haemostatically active toxins which can cause haemorrhage, coagulopathy, inhibition of platelet aggregation and inflammatory response. These effects are attributed to the proteolytic action of SVMPs on extracellular matrix components, plasma proteins and cell-surface proteins. SVMPs are classified into four classes (P-I to P-IV) based on their domain structures. In order to understand the multiple roles played by the domains of P-III SVMPs, a P-III SVMP (BmMP-III) from the venom of Bothrops moojeni was purified, characterized and crystallized. The crystals belonged to space group I4122, with unit-cell parameters a = b = 108.16, c = 196.09 Å. Initially, flash-cooled crystals diffracted poorly to a resolution of about 10 Å. However, a significant improvement in the diffraction resolution was observed upon annealing and a complete data set was collected to 3.3 Å resolution. The asymmetric unit contained one molecule and the structure was determined and partially refined to an R factor of 34%. Structural comparisons indicated that the cysteine-rich domain can adopt different conformations in relation to the catalytic domain, which may modulate the enzyme activity

  11. Extreme Dental Compensation in an Adult Skeletal Class III Malocclusion: 3-Year Follow-up of a Successfully Compromised Treatment.

    Science.gov (United States)

    Estelita, Sérgio; Janson, Guilherme; Chiqueto, Kelly

    2015-01-01

    Nonsurgical orthodontic treatment of a patient with severe skeletal Class III malocclusion, negative overjet, increased overbite and maxillary crowding is described Although the treatment options included an orthodontic-surgical approach, high cost of the surgical procedure was the main reason for extreme dental compensation to have been performed. Four-premolar extraction protocol associated with intermaxillary Class III elastics were used to correct the malocclusion at the expense of increasing the initial dental compensation without producing any noticeable skeletal change. Satisfactory and stable occlusion was achieved with dental and smile esthetics improvement, but the amount of facial changes was limited by the nonsurgical protocol. The clinical results and implications of compensatory treatment as well as its relevance within the patient context are discussed based on scientific evidences. PMID:26349294

  12. Accuracy of Dolphin visual treatment objective (VTO) prediction software on class III patients treated with maxillary advancement and mandibular setback

    OpenAIRE

    Peterman, Robert J.; Jiang, Shuying; Johe, Rene; Mukherjee, Padma M.

    2016-01-01

    Background Dolphin® visual treatment objective (VTO) prediction software is routinely utilized by orthodontists during the treatment planning of orthognathic cases to help predict post-surgical soft tissue changes. Although surgical soft tissue prediction is considered to be a vital tool, its accuracy is not well understood in tow-jaw surgical procedures. The objective of this study was to quantify the accuracy of Dolphin Imaging’s VTO soft tissue prediction software on class III patients tre...

  13. Bone thickness of the infrazygomatic crest area in skeletal Class III growing patients: A computed tomographic study

    International Nuclear Information System (INIS)

    This study was performed to investigate the bone thickness of the infrazygomatic crest area by computed tomography (CT) for placement of a miniplate as skeletal anchorage for maxillary protraction in skeletal Class III children. CT images of skeletal Class III children (7 boys, 9 girls, mean age: 11.4 years) were taken parallel to the Frankfurt horizontal plane. The bone thickness of the infrazygomatic crest area was measured at 35 locations on the right and left sides, perpendicular to the bone surface. The bone was thickest (5.0 mm) in the upper zygomatic bone and thinnest (1.1 mm) in the anterior wall of the maxillary sinus. Generally, there was a tendency for the bone to be thicker at the superior and lateral area of the zygomatic process of the maxilla. There was no clinically significant difference in bone thickness between the right and left sides; however, it was thicker in male than in female subjects. In the infrazygomatic crest area, the superior and lateral area of the zygomatic process of the maxilla had the most appropriate thickness for placement of a miniplate in growing skeletal Class III children with a retruded maxilla.

  14. Bone thickness of the infrazygomatic crest area in skeletal Class III growing patients: A computed tomographic study

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Hyub Soo; Choi, Hang Moon; Choi, Dong Soon; Jang, Insan; Cha, Bong Kuen [College of Dentistry and Research Institute of Oral Science, Gangneung-Wonju National University, Gangneung (Korea, Republic of)

    2013-12-15

    This study was performed to investigate the bone thickness of the infrazygomatic crest area by computed tomography (CT) for placement of a miniplate as skeletal anchorage for maxillary protraction in skeletal Class III children. CT images of skeletal Class III children (7 boys, 9 girls, mean age: 11.4 years) were taken parallel to the Frankfurt horizontal plane. The bone thickness of the infrazygomatic crest area was measured at 35 locations on the right and left sides, perpendicular to the bone surface. The bone was thickest (5.0 mm) in the upper zygomatic bone and thinnest (1.1 mm) in the anterior wall of the maxillary sinus. Generally, there was a tendency for the bone to be thicker at the superior and lateral area of the zygomatic process of the maxilla. There was no clinically significant difference in bone thickness between the right and left sides; however, it was thicker in male than in female subjects. In the infrazygomatic crest area, the superior and lateral area of the zygomatic process of the maxilla had the most appropriate thickness for placement of a miniplate in growing skeletal Class III children with a retruded maxilla.

  15. Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO

    Energy Technology Data Exchange (ETDEWEB)

    Reidick, Christina [Biochemie Intrazellulärer Transportprozesse, Ruhr-Universität Bochum, Bochum 44801 (Germany); El Magraoui, Fouzi; Meyer, Helmut E. [Biomedical Research, Human Brain Proteomics II, Leibniz-Institut für Analytische Wissenschaften-ISAS, Dortmund 44139 (Germany); Stenmark, Harald [Department of Biochemistry, Institute for Cancer Research, Oslo University Hospital, Montebello, Oslo 0310 (Norway); Platta, Harald W., E-mail: harald.platta@rub.de [Biochemie Intrazellulärer Transportprozesse, Ruhr-Universität Bochum, Bochum 44801 (Germany)

    2014-12-23

    The occurrence of cancer is often associated with a dysfunction in one of the three central membrane-involution processes—autophagy, endocytosis or cytokinesis. Interestingly, all three pathways are controlled by the same central signaling module: the class III phosphatidylinositol 3-kinase (PI3K-III) complex and its catalytic product, the phosphorylated lipid phosphatidylinositol 3-phosphate (PtdIns3P). The activity of the catalytic subunit of the PI3K-III complex, the lipid-kinase VPS34, requires the presence of the membrane-targeting factor VPS15 as well as the adaptor protein Beclin 1. Furthermore, a growing list of regulatory proteins associates with VPS34 via Beclin 1. These accessory factors define distinct subunit compositions and thereby guide the PI3K-III complex to its different cellular and physiological roles. Here we discuss the regulation of the PI3K-III complex components by ubiquitination and SUMOylation. Especially Beclin 1 has emerged as a highly regulated protein, which can be modified with Lys11-, Lys48- or Lys63-linked polyubiquitin chains catalyzed by distinct E3 ligases from the RING-, HECT-, RBR- or Cullin-type. We also point out other cross-links of these ligases with autophagy in order to discuss how these data might be merged into a general concept.

  16. Class III β-tubulin overexpression within the tumor microenvironment is a prognostic biomarker for poor overall survival in ovarian cancer patients treated with neoadjuvant carboplatin/paclitaxel.

    Science.gov (United States)

    Roque, Dana M; Buza, Natalia; Glasgow, Michelle; Bellone, Stefania; Bortolomai, Ileana; Gasparrini, Sara; Cocco, Emiliano; Ratner, Elena; Silasi, Dan-Arin; Azodi, Masoud; Rutherford, Thomas J; Schwartz, Peter E; Santin, Alessandro D

    2014-01-01

    Critics have suggested that neoadjuvant chemotherapy (NACT) followed by interval debulking may select for resistant clones or cancer stem cells when compared to primary cytoreduction. β-tubulins are chemotherapeutic targets of taxanes and epothilones. Class III β-tubulin overexpression has been linked to chemoresistance and hypoxia. Herein, we describe changes in class III β-tubulin in patients with advanced ovarian carcinoma in response to NACT, in relationship to clinical outcome, and between patients who underwent NACT versus primary debulking; we characterize in vitro chemosensitivity to paclitaxel/patupilone of cell lines established from this patient population, and class III β-tubulin expression following repeated exposure to paclitaxel. Using immunohistochemistry, we observed among 22 paired specimens obtained before/after NACT decreased expression of class III β-tubulin following therapy within stroma (p=0.07), but not tumor (p=0.63). Poor median overall survival was predicted by high levels of class III β-tubulin in both tumor (HR 3.66 [1.11,12.05], p=0.03) and stroma (HR 4.53 [1.28,16.1], p=0.02). Class III β-tubulin expression by quantitative-real-time-polymerase-chain-reaction was higher among patients who received NACT (n=12) compared to primary cytoreduction (n=14) (mean±SD fold-change: 491.2±115.9 vs. 224.1±55.66, p=0.037). In vitro subculture with paclitaxel resulted in class III β-tubulin upregulation, however, cell lines that overexpressed class III β-tubulin remained sensitive to patupilone. Overexpression of class III β-tubulin in patients dispositioned to NACT may thus identify an intrinsically aggressive phenotype, and predict poor overall survival and paclitaxel resistance. Decreases in stromal expression may represent normalization of the tumor microenvironment following therapy. Epothilones warrant study for patients who have received neoadjuvant carboplatin and paclitaxel. PMID:24005572

  17. Orthodontic and dentofacial orthopedic management of juvenile idiopathic arthritis: a systematic review of the literature.

    Science.gov (United States)

    von Bremen, J; Ruf, S

    2011-08-01

    To systematically review the literature published on orthodontic treatment principles in patients with juvenile idiopathic arthritis (JIA). Several electronic databases (PubMed, Medpilot, Web of Science, and DIMDI) and orthodontic and rheumatologic literature were systematically searched for studies published until May 2010. The articles were rated by two independent reviewers and included after three selection steps (title-abstract-full text). Articles had to be studies performed on ≥ 5 patients with a disease onset before the age of 16. The selection process resulted in the inclusion of three publications on dentofacial orthopedics and six on combined surgical orthodontic therapy. The three studies on dentofacial orthopedics aimed to improve the mandibular retrusion by means of removable functional appliances (activator). Whereas these orthodontic approaches comprised relatively large and homogeneous patient samples (14, 22, and 72 subjects, aged 6-16), the surgical studies were basically case series with a large age span of the patients (5-12 subjects, aged 10-44). In these surgical treatment approaches, orthodontics was limited to pre-surgical leveling and post-surgical finishing, while the skeletal discrepancy was treated surgically by a variety of techniques (costochondral grafts, bilateral sagittal spilt osteotomy, Le Fort I, and genioplasty). The treatment goals of both approaches were improvement of esthetics and function and/or pain reduction, and both approaches showed satisfactory results. Because of the heterogeneity of the subject material and the low level of evidence of the papers, it is difficult to draw any conclusions on the orthodontic/dentofacial orthopedic management of JIA. It appears as if removable functional appliances may be beneficial in adolescent patients with JIA. PMID:21771266

  18. Orthodontic treatment of a transposed maxillary canine and first premolar in a young patient with Class III malocclusion.

    Science.gov (United States)

    Gracco, Antonio; Siviero, Laura; Perri, Alessandro; Favero, Lorenzo; Stellini, Edoardo

    2015-11-01

    A 12-year-old girl was referred to our clinic for evaluation of an unaesthetic dental appearance. All permanent teeth were erupted, while the deciduous maxillary right canine was retained. Cone-beam computed tomography revealed a complete transposition of the maxillary left canine and first premolar involving both the crowns and the roots. Initial cephalometric analysis showed a skeletal Class III pattern, with a slight maxillary retrusion and a compensated proclination of the upper incisors. The patient's teeth were considered to be in the correct position; therefore, we decided to attempt treatment by correcting the transposition and using only orthodontic compensation of the skeletal Class III malocclusion. After 25 months of active orthodontic treatment, the patient had a Class I molar and canine relationship on both sides, with ideal overbite and overjet values. Her profile was improved, her lips were competent, and cephalometric evaluation showed acceptable maxillary and mandibular incisor inclinations. The final panoramic radiograph showed that good root parallelism was achieved. Two-year follow-up intraoral photography showed stable results. PMID:26629478

  19. Effects of Lifestyle Interventions That Include a Physical Activity Component in Class II and III Obese Individuals: A Systematic Review and Meta-Analysis

    OpenAIRE

    Baillot, Aurélie; Romain, Ahmed J.; Boisvert-Vigneault, Katherine; Audet, Mélisa; Baillargeon, Jean Patrice; Dionne, Isabelle J.; Valiquette, Louis; Chakra, Claire Nour Abou; Avignon, Antoine; Langlois, Marie-France

    2015-01-01

    Background In class II and III obese individuals, lifestyle intervention is the first step to achieve weight loss and treat obesity-related comorbidities before considering bariatric surgery. A systematic review, meta-analysis, and meta-regression were performed to assess the impact of lifestyle interventions incorporating a physical activity (PA) component on health outcomes of class II and III obese individuals. Methods An electronic search was conducted in 4 databases (Medline, Scopus, CIN...

  20. Class III β-tubulin overexpression within the tumor microenvironment is a prognostic biomarker for poor overall survival in ovarian cancer patients treated with neoadjuvant carboplatin/paclitaxel

    OpenAIRE

    Roque, Dana M; Buza, Natalia; Glasgow, Michelle; Bellone, Stefania; Bortolomai, Ileana; Gasparrini, Sara; Cocco, Emiliano; Ratner, Elena; Silasi, Dan-Arin; Azodi, Masoud; Rutherford, Thomas J.; Schwartz, Peter E.; Alessandro D Santin

    2013-01-01

    Critics have suggested that neoadjuvant chemotherapy (NACT) followed by interval debulking may select for resistant clones or cancer stem cells when compared to primary cytoreduction. β-tubulins are chemotherapeutic targets of taxanes and epothilones. Class III β-tubulin overexpression has been linked to chemoresistance and hypoxia. Herein, we describe changes in class III β-tubulin in patients with advanced ovarian carcinoma in response to NACT, in relationship to clinical outcome, and betwe...

  1. Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity.

    Science.gov (United States)

    Radwan, Asma; Amidon, Gordon L; Langguth, Peter

    2012-10-01

    A negative food effect, i.e. a decrease in bioavailability upon the co-administration of compounds together with food, has been attributed particularly with high solubility/low permeability compounds (BCS class III). Different mechanisms have been proposed including intestinal dilution leading to a lower concentration gradient across the intestinal wall as well as binding of the active pharmaceutical ingredient to food components in the intestine and thereby decreasing the fraction of the dose available for absorption. These mechanisms refer primarily to the compound and not to the dosage form. An increase in viscosity of the dissolution fluid will in particular affect the absorption of BCS type III compounds with preferential absorption in the upper small intestine if the API release is delayed from the dosage form. The present study demonstrated that the increase in viscosity of the dissolution medium, following ingestion of a solid meal, may drastically reduce disintegration and dissolution. For that purpose the viscosity of the standard FDA meal was determined and simulated by solutions of HPMC in buffer. As model formulations, three commercially available tablets containing trospium chloride, a BCS class III m-cholinoreceptor antagonist was used. Trospium chloride drug products have been described to undergo a negative food effect of more than 80% following ingestion with food. The tablets showed prolonged disintegration times and reduced dissolution rates in viscous media, which could be attributed to changes in the liquid penetration rates. The effect was particularly significant for film-coated tablets relative to uncoated dosage forms. The results show the necessity of considering media viscosity when designing in vitro models of drug release for BCS type III drug formulations. PMID:22782559

  2. Estudo comparativo cefalométrico dos padrões dentofaciais de indivíduos portadores de oclusão normal e de más oclusões de Angle Comparative cephalometric study of dentofacial patterns of individuals with normal occlusion and Angle malocclusions

    Directory of Open Access Journals (Sweden)

    Julio César Mota Pereira

    2011-10-01

    Full Text Available OBJETIVO: avaliar os padrões dentofaciais de pacientes portadores de oclusão normal e más oclusões de Angle quanto a possíveis diferenças entre as grandezas estudadas, em relação ao sexo, dentro de cada grupo e entre os grupos. MÉTODOS: a amostra constou de 200 telerradiografias cefalométricas laterais obtidas de jovens brasileiros, de ambos os sexos, na faixa etária de 11 anos e 2 meses a 19 anos e 10 meses, apresentando dentição permanente. O material foi dividido, quanto ao tipo de oclusão, em cinco grupos: um de pacientes portadores de oclusão normal, e quatro de pacientes portadores de más oclusões de Angle, sendo cada grupo dividido igualmente quanto ao sexo. Foram avaliadas grandezas cefalométricas angulares e lineares. RESULTADOS: na grande maioria das grandezas, os sexos masculino e feminino não diferiram; entre os grupos, a posição da maxila não mostrou diferença significativa, o retrognatismo mandibular foi marcante nos grupos de Classe II divisões 1ª e 2ª e foram observados alguns desequilíbrios verticais com diferenças significativas; o padrão foi hipodivergente para os grupos de oclusão normal e Classe II, divisão 2ª, e neutro para os grupos de Classe I; Classe II, divisão 1ª; e Classe III; a compensação dentoalveolar foi evidente nos grupos de Classe III e de Classe II, divisão 2ª; o grupo de oclusão normal apresentou perfil mais convexo que os padrões americanos. CONCLUSÃO: foi possível configurar, de forma geral, algumas características da morfologia facial para alguns tipos de más oclusões. Entretanto, existe a necessidade de avaliar a face individualmente, pois algumas características permeiam entre os diferentes tipos de oclusão.OBJECTIVE: To determine the dentofacial patterns in patients presenting normal occlusion and Angle malocclusions, evaluating the possible differences in the studied measurements, considering the gender, the differences within each group and the

  3. Comparison of the dentofacial patterns for native Greek and American-Caucasian adolescents.

    Science.gov (United States)

    Argyropoulos, E; Sassouni, V

    1989-03-01

    The study of the craniofacial relations and variations in man has long been used to differentiate various racial groups in physical anthropology. Morphologic features of different races and ethnic groups are not randomly distributed but appear in geographic clusters. Richardson wonders whether there is only one race, comprising ethnic groups separated by cultural, climatic, and geographic boundaries, causing subtle changes in facial morphology. Since the introduction of roentgenographic cephalometry in orthodontics, several methods of analysis have been developed for clinical diagnosis and treatment planning. Also, these methods have been used to establish the cephalometric norms of different ethnic groups: American Negro, Australian aborigine, American Mexican, Norwegian, Indian, Japanese, Swedish, and Iranian. Sassouni, Ricketts, and others have concluded that norms differ between Caucasians and other ethnic and racial groups. Ethnic differences in facial traits do exist. Awareness of the normal dentofacial pattern of each ethnic group will undoubtedly ensure better success of treatment to establish optimal facial harmony. These conclusions prompted the present investigation, which compares Greek and American-Caucasian dentofacial patterns of adolescents, and provides information on the facial characteristics of Greek adolescents. To date, no similar study has been made. PMID:2923103

  4. TGF-{beta}-stimulated aberrant expression of class III {beta}-tubulin via the ERK signaling pathway in cultured retinal pigment epithelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Eun Jee [Department of Ophthalmology, National Health Insurance Corporation Ilsan Hospital, Gyeonggi-do (Korea, Republic of); Chun, Ji Na; Jung, Sun-Ah [Konyang University Myunggok Medical Research Institute, Kim' s Eye Hospital, Konyang University College of Medicine, Seoul (Korea, Republic of); Cho, Jin Won [Department of Biology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749 (Korea, Republic of); Lee, Joon H., E-mail: joonhlee@konyang.ac.kr [Konyang University Myunggok Medical Research Institute, Kim' s Eye Hospital, Konyang University College of Medicine, Seoul (Korea, Republic of)

    2011-11-18

    Highlights: Black-Right-Pointing-Pointer TGF-{beta} induces aberrant expression of {beta}III in RPE cells via the ERK pathway. Black-Right-Pointing-Pointer TGF-{beta} increases O-GlcNAc modification of {beta}III in RPE cells. Black-Right-Pointing-Pointer Mature RPE cells have the capacity to express a neuron-associated gene by TGF-{beta}. -- Abstract: The class III {beta}-tubulin isotype ({beta}{sub III}) is expressed exclusively by neurons within the normal human retina and is not present in normal retinal pigment epithelial (RPE) cells in situ or in the early phase of primary cultures. However, aberrant expression of class III {beta}-tubulin has been observed in passaged RPE cells and RPE cells with dedifferentiated morphology in pathologic epiretinal membranes from idiopathic macular pucker, proliferative vitreoretinopathy (PVR) and proliferative diabetic retinopathy (PDR). Transforming growth factor-{beta} (TGF-{beta}) has been implicated in dedifferentiation of RPE cells and has a critical role in the development of proliferative vitreoretinal diseases. Here, we investigated the potential effects of TGF-{beta} on the aberrant expression of class III {beta}-tubulin and the intracellular signaling pathway mediating these changes. TGF-{beta}-induced aberrant expression and O-linked-{beta}-N-acetylglucosamine (O-GlcNac) modification of class III {beta}-tubulin in cultured RPE cells as determined using Western blotting, RT-PCR and immunocytochemistry. TGF-{beta} also stimulated phosphorylation of ERK. TGF-{beta}-induced aberrant expression of class III {beta}-tubulin was significantly reduced by pretreatment with U0126, an inhibitor of ERK phosphorylation. Our findings indicate that TGF-{beta} stimulated aberrant expression of class III {beta}-tubulin via activation of the ERK signaling pathway. These data demonstrate that mature RPE cells have the capacity to express a neuron-associated gene in response to TGF-{beta} stimulation and provide useful information

  5. TGF-β-stimulated aberrant expression of class III β-tubulin via the ERK signaling pathway in cultured retinal pigment epithelial cells

    International Nuclear Information System (INIS)

    Highlights: ► TGF-β induces aberrant expression of βIII in RPE cells via the ERK pathway. ► TGF-β increases O-GlcNAc modification of βIII in RPE cells. ► Mature RPE cells have the capacity to express a neuron-associated gene by TGF-β. -- Abstract: The class III β-tubulin isotype (βIII) is expressed exclusively by neurons within the normal human retina and is not present in normal retinal pigment epithelial (RPE) cells in situ or in the early phase of primary cultures. However, aberrant expression of class III β-tubulin has been observed in passaged RPE cells and RPE cells with dedifferentiated morphology in pathologic epiretinal membranes from idiopathic macular pucker, proliferative vitreoretinopathy (PVR) and proliferative diabetic retinopathy (PDR). Transforming growth factor-β (TGF-β) has been implicated in dedifferentiation of RPE cells and has a critical role in the development of proliferative vitreoretinal diseases. Here, we investigated the potential effects of TGF-β on the aberrant expression of class III β-tubulin and the intracellular signaling pathway mediating these changes. TGF-β-induced aberrant expression and O-linked-β-N-acetylglucosamine (O-GlcNac) modification of class III β-tubulin in cultured RPE cells as determined using Western blotting, RT-PCR and immunocytochemistry. TGF-β also stimulated phosphorylation of ERK. TGF-β-induced aberrant expression of class III β-tubulin was significantly reduced by pretreatment with U0126, an inhibitor of ERK phosphorylation. Our findings indicate that TGF-β stimulated aberrant expression of class III β-tubulin via activation of the ERK signaling pathway. These data demonstrate that mature RPE cells have the capacity to express a neuron-associated gene in response to TGF-β stimulation and provide useful information towards understanding the pathogenesis of proliferative vitreoretinal diseases.

  6. Assessment of the changes in quality of life of patients with class II and III deformities during and after orthodontic-surgical treatment.

    Science.gov (United States)

    Baherimoghaddam, T; Tabrizi, R; Naseri, N; Pouzesh, A; Oshagh, M; Torkan, S

    2016-04-01

    The aim of this longitudinal study was to assess and compare the oral health-related quality of life (OHRQoL) of patients with class II and III deformities during and after orthodontic-surgical treatment. Thirty class III and 28 class II patients were evaluated at baseline (T0), just prior to surgery (T1), at 6 months after surgery (T2), and at 12 months after debonding (T3). OHRQoL was assessed using the Oral Health Impact Profile (OHIP-14). Friedman two-way analysis of variance and the Wilcoxon signed-rank test were performed to compare the relative changes in OHRQoL during treatment. Significant changes in the overall OHIP-14 scores were observed during and after orthodontic-surgical treatment in both groups. During the pre-surgical stage, psychological discomfort and psychological disability decreased in class III patients, and class II patients experienced a significant deterioration in psychological discomfort during the same period. Six months after surgery, patients in both groups showed improvements in psychological discomfort, social disability, and handicap. Physical disability and functional limitation showed further improvement at 12 months after debonding in class II patients. This study reaffirms that orthodontic-surgical treatment has a significant effect on the OHRQoL of class III and class II patients. PMID:26603194

  7. Impact of Dentofacial Deformity on Quality of Life: Age and Gender Differences Evaluated Through OQLQ, OHIP and SF36

    Directory of Open Access Journals (Sweden)

    Marcelo Carlos Bortoluzzi

    2015-09-01

    Full Text Available Objectives: The aim of this study was to verify the impact of dentofacial deformity on quality of life and explore gender and age differences. Material and Methods: The impact of dentofacial deformity (DD on quality of life was evaluated through questionnaires; Short Form Health Survey (SF36, Oral Health Impact Profile Questionnaire (OHIP, Orthognathic Quality of Life Questionnaire (OQLQ and a single question answered by a Visual Analogue Scale. Results: Significant differences between male and female patients were observed in domains of OQLQ (oral function, P = 0.006; awareness of facial deformity, P = 0.018; and facial aesthetics, P < 0.001 and OHIP (physical pain, P = 0.006; psychological discomfort, P = 0.007; psychological disability, P = 0.006; and handicap, P = 0.01. Conclusions: The impact of dentofacial deformity was more pronounced in female Brazilian population. Age of patients with dentofacial deformity produced impacts over quality of life in different ways and according to the applied questionnaire and the interaction between age and gender may also produce different impacts in patients with dentofacial deformity. The domains of Orthognathic Quality of Life Questionnaire, Oral Health Impact Profile Questionnaire and Short Form Health Survey showed unaccepted distances in the pattern of answer rising doubts of their ability to assess quality of life as a generic and broad concept. There is a necessity to create a single quality of life instrument capable to measure impacts with sensitivity and specificity and from a generic concept to condition-specific health problem.

  8. Intervenção ortocirúrgica em paciente adolescente com acentuada displasia esquelética de Classe III Orthodontic-surgical treatment in youthful patient with severe skeletal Class III malocclusion

    Directory of Open Access Journals (Sweden)

    Andressa Otranto de Britto Teixeira

    2007-10-01

    Full Text Available INTRODUÇÃO: a má oclusão de Classe III é caracterizada por uma discrepância esquelética ântero-posterior, podendo ou não estar acompanhada de alterações verticais, mas comumente apresenta alterações transversais associadas. O aspecto facial fica comprometido nesses pacientes, sendo esse um dos fatores que os motivam a procurar o tratamento ortodôntico. Quando o paciente encontra-se na faixa de 8 a 10 anos de idade, uma abordagem precoce é indicada. Quando o paciente é adulto e o crescimento já cessou, o tratamento vai ser decidido entre a camuflagem ortodôntica e os procedimentos ortocirúrgicos clássicos. O problema quanto à decisão terapêutica está no paciente adolescente, com acentuadas Classes III esqueléticas, quando os procedimentos interceptativos não mais surtirão o efeito desejado e as alterações faciais são muito significativas. Ainda haverá crescimento e muitas vezes há comprometimento psicossocial ou funcional. OBJETIVO: propor uma abordagem cirúrgica precoce como alternativa de tratamento para esses pacientes, mesmo que uma segunda cirurgia seja necessária após o término do crescimento. DISCUSSÃO: para se propor essa terapia, vários critérios devem ser observados para que realmente o paciente tenha benefícios com esta intervenção precoce, como pouca discrepância intra-arco e possibilidade de preparo ortodôntico pré-cirúrgico rápido. CONCLUSÃO: deve-se ter ciência que um segundo tratamento ortocirúrgico provavelmente se fará necessário após o término do crescimento e que esse tipo de tratamento não deve ser empregado como rotina.INTRODUCTION: Class III malocclusion is characterized by an anterior-posterior skeletal discrepancy that may or may not be combined with vertical alterations, but it commonly presents transverse disharmony associated. The facial aspect is affected in these patients, which is one of the factors that motivate them to look for orthodontic treatment. For young

  9. Management of skeletal class III malocclusion with a palatally impacted cuspid

    Directory of Open Access Journals (Sweden)

    Chris HN Chang

    2012-01-01

    Maintain the A-P position of the maxilla.Extrude lower molars to open the VDO by clockwise rotation to effectively retract the mandible relative to the maxilla.Retract the mandibular incisors.Correct the anterior X-bite and align the midlinesEstablish a normal overjet and overbite in a mutually protected, Class I occlusion.Retract lower lip to improve facial balance 0.022-in Damon D3® (standard torque and Inspire Ice® brackets ( Ormco were used. The simplicity of mechanics is illustrated

  10. Oral Rehabilitation With Orthognathic Surgery After Dental Implant Placement for Class III Malocclusion With Skeletal Asymmetry and Posterior Bite Collapse.

    Science.gov (United States)

    Ohba, Seigo; Nakatani, Yuya; Kawasaki, Takako; Tajima, Nobutaka; Tobita, Takayoshi; Yoshida, Noriaki; Sawase, Takashi; Asahina, Izumi

    2015-08-01

    Increasing numbers of older patients are seeking orthognathic surgery to treat jaw deformity. However, orthodontic and orthognathic surgical treatment is difficult in cases without occlusal vertical stop. A 55-year-old man presented with Class III malocclusion and mandibular protrusion including esthetic problems and posterior bite collapse. He underwent dental implant treatment to reconstruct an occlusal vertical stop before orthognathic surgery. His occlusal function and esthetic problems improved after surgery, and his skeletal and occlusal stability has been maintained for 6 years. Dental implant placement at appropriate positions could help to determine the position of the proximal segment at orthognathic surgery and could shorten the time required to restore esthetic and occlusal function. This case demonstrates how skeletal and dental stability can be maintained long after surgery in a patient with jaw deformity and posterior bite collapse. PMID:26035376

  11. Novel three-dimensional position analysis of the mandibular foramen in patients with skeletal class III mandibular prognathism

    Science.gov (United States)

    Kim, Yeon-Ho; Won, Yu-Jin; Kim, Moon-Key

    2016-01-01

    Purpose To analyze the relative position of the mandibular foramina (MnFs) in patients diagnosed with skeletal class III malocclusion. Materials and Methods Computed tomography (CT) images were collected from 85 patients. The vertical lengths of each anatomic point from the five horizontal planes passing through the MnF were measured at the coronoid process, sigmoid notch, condyle, and the gonion. The distance from the anterior ramus point to the posterior ramus point on the five horizontal planes was designated the anteroposterior horizontal distance of the ramus for each plane. The perpendicular distance from each anterior ramus point to each vertical plane through the MnF was designated the horizontal distance from the anterior ramus to the MnF. The horizontal and vertical positions were examined by regression analysis. Results Regression analysis showed the heights of the coronoid process, sigmoid notch, and condyle for the five horizontal planes were significantly related to the height of the MnF, with the highest significance associated with the MnF-mandibular plane (coefficients of determination (R2): 0.424, 0.597, and 0.604, respectively). The horizontal anteroposterior length of the ramus and the distance from the anterior ramus point to the MnF were significant by regression analysis. Conclusion The relative position of the MnF was significantly related to the vertical heights of the sigmoid notch, coronoid process, and condyle as well as to the horizontal anteroposterior length of the ascending ramus. These findings should be clinically useful for patients with skeletal class III mandibular prognathism. PMID:27358814

  12. Comparative study of design of piping supports class 1, 2 and 3 considering german code KTA and ASME III - NF

    International Nuclear Information System (INIS)

    The objective of this paper is developing a comparative study of the design criteria for class 1, 2, 3 piping supports considering the American Code ASME Section III - NF and the German Code KTA 3205.1 to the Primary Circuit, KTA 3205.2 to the others systems and KTA 3205.3 series-production standards supports of a PWR nuclear power plant. An additional purpose of the paper is a general analysis of the main design concepts of the American Code ASME Boiler and Pressure Vessel Code, Section III, Division 1 and German Nuclear Design Code KTA that was performed in order to aid the comparative study proposed. The relevance of this study is to show the differences between codes ASME and KTA since they were applied in the design of the Nuclear Power Plants Angra 1 and Angra 2, and to the design of Angra 3, which is at the moment under construction. It is also considered their use in the design of nuclear installations such as RMB - Reator MultiProposito Brasileiro and LABGENE - Laboratorio de Geracao Nucleoeletrica. (author)

  13. Social class, political power, and the state: their implications in medicine--part III.

    Science.gov (United States)

    Navarro, V

    1977-01-01

    This is the third part of an article on the distribution of power and the nature of the state in Western industrialized societies and their implications in medicine. Parts I and II were published in the preceding issue of this Journal. Part I presented a critique of contemporary theories of the Western system of power; discussed the countervailing pluralist and power of elite theories, as well as those of bureaucratic and professional control; and concluded with an examination of the Marxist theories of economic determinism, structural determinism, and corporate statism. Part II presented a Marxist theory of the role, nature, and characteristics of state intervention. Part III focuses on the mode of that intervention and the reasons for its growth, with an added analysis of the attributes of state intervention in the health sector, and of the dialectical relationship between its growth and the current fiscal crisis of the state. In all three parts, the focus is on Western European countries and on North America, with many examples and categories from the area of medicine. PMID:870557

  14. 安氏Ⅲ类骨性Ⅲ类与安氏I类错牙合畸形舌体形态位置及舌骨位置的比较研究%Comparative Study between the tongue shape and hyoid bone position in Angle Class III and Skeletal Class III Malocclusion and Those in Angle Class I Malocclusion

    Institute of Scientific and Technical Information of China (English)

    袁小平; 朗么磋; 王昊

    2014-01-01

    Objective To compare the tongue shape and hyoid bone position in Angle class III and skeletal class III malocclusion with those in Angle class I malocclusion. Methods 46 cases were enrolled, including 26 cases of Angle class III and skeletal III maloc-clusion and 20 cases of Angle class I malocclusion;the dorsum of tongues were coated with barium sulfate and lateral X-ray of the head was taken;17 spots on the tongue and hyoid bone were selected and traced, and 13 measured values were analyzed. Results The tongue tips of the patients of Angle class III and skeletal class III malocclusion were positioned more anterior(O-T1), the hyoid more posterior (O-T7)and the tongue middle more inferior(O-T2,T3)compared with the patients of Angle class I malocclusion, the difference was of statistical significance (P<0.05); The tongues of patients of Angle class III and skeletal class III malocclusion were longer than those of patients of Angle class I malocclusion, the difference was of obvious statistical significance (P<0.01);The hyoid bone of patients of An-gle class III and skeletal class III malocclusion was positioned more anterior inferiorly than that of patients of Angle class I malocclu-sion, the difference was of obvious statistical significance (P<0.01, P<0.01). Conclusions The tongue shape and hyoid bone position of patients of Angle class III and skeletal class III malocclusion are of certain difference from those of patients of Angle class I malocclu-sion.%目的:比较安氏Ⅲ类骨性Ⅲ类与安氏I类错牙合畸形舌体形态位置及舌骨位置。方法对46例患者(实验组安氏Ⅲ类骨性Ⅲ类26例,对照组安氏I类20例)拍摄头侧位X光片并在舌背涂抹硫酸钡糊剂,选择舌体及舌骨的17个点进行描记,对13个测量值进行分析。结果(1)安氏Ⅲ类骨性Ⅲ类错牙合畸形患者比安氏I类错牙合畸形患者舌尖位置偏前(O-T1)、舌根位置偏后(O-T7)、舌体中断偏低(O-T2,T3

  15. Facial and occlusal esthetic improvements of an adult skeletal Class III malocclusion using surgical, orthodontic, and implant treatment

    Science.gov (United States)

    de Almeida Cardoso, Mauricio; de Avila, Erica Dorigatti; Guedes, Fabio Pinto; Battilani Filho, Valter Antonio Ban; Capelozza Filho, Leopoldino; Correa, Marcio Aurelio; Nary Filho, Hugo

    2016-01-01

    The aim of this clinical report is to describe the complex treatment of an adult Class III malocclusion patient who was disappointed with the outcome of a previous oral rehabilitation. Interdisciplinary treatment planning was performed with a primary indication for implant removal because of marginal bone loss and gingival recession, followed by orthodontic and surgical procedures to correct the esthetics and skeletal malocclusion. The comprehensive treatment approach included: (1) implant removal in the area of the central incisors; (2) combined orthodontic decompensation with mesial displacement and forced extrusion of the lateral incisors; (3) extraction of the lateral incisors and placement of new implants corresponding to the central incisors, which received provisional crowns; (4) orthognathic surgery for maxillary advancement to improve occlusal and facial relationships; and finally, (5) orthodontic refinement followed by definitive prosthetic rehabilitation of the maxillary central incisors and reshaping of the adjacent teeth. At the three-year follow-up, clinical and radiographic examinations showed successful replacement of the central incisors and improved skeletal and esthetic appearances. Moreover, a Class II molar relationship was obtained with an ideal overbite, overjet, and intercuspation. In conclusion, we report the successful esthetic anterior rehabilitation of a complex case in which interdisciplinary treatment planning improved facial harmony, provided gingival architecture with sufficient width and thickness, and improved smile esthetics, resulting in enhanced patient comfort and satisfaction. This clinical case report might be useful to improve facial esthetics and occlusion in patients with dentoalveolar and skeletal defects. PMID:26877982

  16. Botrytis cinerea virulence is drastically reduced after disruption of chitin synthase class III gene (Bcchs3a).

    Science.gov (United States)

    Soulié, Marie-Christine; Perino, Claude; Piffeteau, Annie; Choquer, Mathias; Malfatti, Pierrette; Cimerman, Agnès; Kunz, Caroline; Boccara, Martine; Vidal-Cros, Anne

    2006-08-01

    Botrytis cinerea is an important phytopathogenic fungus requiring new methods of control. Chitin biosynthesis, which involves seven classes of chitin synthases, could be an attractive target. A fragment encoding one of the class III enzymes was used to disrupt the corresponding Bcchs3a gene in the B. cinerea genome. The resulting mutant exhibited a 39% reduction in its chitin content and an 89% reduction in its in vitro chitin synthase activity, compared with the wild-type strain. Bcchs3a mutant was not affected in its growth in liquid medium, neither in its production of sclerotia, micro- and macroconidia. In contrast, the mutant Bcchs3a was severely impaired in its growth on solid medium. Counterbalancing this defect in radial growth, Bcchs3a mutant presented a large increase in hyphal ramification, resulting in an enhanced aerial growth. Observations by different techniques of microscopy revealed a thick extracellular matrix around the hyphal tips. Moreover, Bcchs3a mutant had a largely reduced virulence on Vitis vinifera and Arabidopsis thaliana leaves. PMID:16882034

  17. 40 CFR Figure C-3 to Subpart C of... - Illustration of the Slope and Intercept Limits for Class II and Class III PM10−2.5 Candidate...

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Illustration of the Slope and Intercept Limits for Class II and Class III PM10â2.5 Candidate Equivalent Methods C Figure C-3 to Subpart C of Part... Candidate Methods and Reference Methods Pt. 53, Subpt. C, Fig. C-3 Figure C-3 to Subpart C of Part...

  18. Post-surgical dentofacial deformities and dental treatment needs in cleft-lip-palate children: A clinical study

    OpenAIRE

    V. Krishna Priya; J Sharada Reddy; Ramakrishna, Y.; C Pujita Reddy

    2011-01-01

    Background: Cleft lip and palate is a common congenital defect. It is one of the most common facial deformities occurring in major racial and ethnic groups. Aims: The aim of the present study was to record the post-surgical dentofacial deformities in operated cleft lip and palate children, as well as to assess the multitude and magnitude of their dental and other related problems so as to formulate an appropriate treatment plan for complete oral rehabilitation of these children. Materials and...

  19. The influence of children's dentofacial appearance on their social attractiveness as judged by peers and lay adults.

    Science.gov (United States)

    Shaw, W C

    1981-04-01

    The purpose of this study was to determine whether the social attractiveness of a child would be influenced by his or her dentofacial appearance. Black and white photographs of an attractive boy and girl and an unattractive boy and girl were obtained and modified so that, for each face, five different photographic versions were available. In each version, the child's face was standardized except that a different dentofacial arrangement was demonstrated. These were normal incisors, prominent incisors, a missing lateral incisor, severely crowded incisors, and unilateral cleft lip. Each photograph was viewed by a different group of forty-two children and forty-two adults, equally divided as to sex. Their impressions of the depicted child's social attractiveness were recorded on visual analogue scales. The experimental procedure was such that the effect and interaction of different levels of facial attractiveness, different dentofacial arrangements, sex of the photographed child, and sex of the judge could be analyzed. The hypothesis that children with a normal dental appearance would be judged to be better looking, more desirable as friends, more intelligent, and less likely to behave aggressively was upheld. PMID:6939333

  20. Preventing an identity crisis: unexpected co-expression of class III beta-tubulin and glial fibrillary acidic protein in human fetal astrocytes in culture

    Czech Academy of Sciences Publication Activity Database

    Katsetos, C.D.; Dráberová, Eduarda; Del Valle, L.; Bertrand, L.; Agamanolis, D.P.; de Chadarévian, J.-P.; Legido, A.; Dráber, Pavel

    2007-01-01

    Roč. 26, č. 11 (2007), s. 107-107. ISSN 0364-5134 R&D Projects: GA MŠk LC545; GA ČR GA204/05/2375 Institutional research plan: CEZ:AV0Z50520514 Keywords : class III beta-tubulin * fetal glia Subject RIV: EB - Genetics ; Molecular Biology

  1. Dance-based exercise program in rheumatoid arthritis. Feasibility in individuals with American College of Rheumatology functional class III disease.

    Science.gov (United States)

    Noreau, L; Moffet, H; Drolet, M; Parent, E

    1997-01-01

    Many studies have demonstrated that aerobic exercise training is beneficial to prevent physical deconditioning in persons with rheumatoid arthritis (RA) without inducing adverse effects on individual's joints and general health. After significant results in individuals with RA (Functional Class I and II), the present study was conducted to demonstrate the feasibility of a modified dance-based exercise program to improve the physical fitness and psychological state of persons with RA (Class III). Ten (10) female subjects (mean age, 54 +/- 10 years) participated in an eight-week exercise program (twice weekly). Health status, use of medication, joint pain and swelling, cardiorespiratory fitness, activity of daily living, and psychological state were assessed before and after the training program. A high level of participation has been maintained by the participants (mean = 14.8/16 sessions). Most of them were able to perform a maximal exercise test on treadmill and reached 90% of the predicted heart rate at maximal exercise. No significant gain in aerobic power was observed for the group as a whole, but four subjects showed improvements of between 10% and 20% of their cardiorespiratory fitness. Positive changes in depression, anxiety, fatigue, and tension were observed after the eight-week exercise program. No deleterious effect on the health status was observed. These findings provide some evidences as to the feasibility of submitting individuals with RA to a modified dance-exercise program. Further studies, however, are required to determine the long-term effect of weight-bearing exercise on the health status of individuals with RA. PMID:9129516

  2. A Survey of Nucleotide Cyclases in Actinobacteria: Unique Domain Organization and Expansion of the Class III Cyclase Family in Mycobacterium tuberculosis

    Directory of Open Access Journals (Sweden)

    Sandhya S. Visweswariah

    2004-01-01

    Full Text Available Cyclic nucleotides are well-known second messengers involved in the regulation of important metabolic pathways or virulence factors. There are six different classes of nucleotide cyclases that can accomplish the task of generating cAMP, and four of these are restricted to the prokaryotes. The role of cAMP has been implicated in the virulence and regulation of secondary metabolites in the phylum Actinobacteria, which contains important pathogens, such as Mycobacterium tuberculosis, M. leprae, M. bovis and Corynebacterium, and industrial organisms from the genus Streptomyces. We have analysed the actinobacterial genome sequences found in current databases for the presence of different classes of nucleotide cyclases, and find that only class III cyclases are present in these organisms. Importantly, prominent members such as M. tuberculosis and M. leprae have 17 and 4 class III cyclases, respectively, encoded in their genomes, some of which display interesting domain fusions seen for the first time. In addition, a pseudogene corresponding to a cyclase from M. avium has been identified as the only cyclase pseudogene in M. tuberculosis and M. bovis. The Corynebacterium and Streptomyces genomes encode only a single adenylyl cyclase each, both of which have corresponding orthologues in M. tuberculosis. A clustering of the cyclase domains in Actinobacteria reveals the presence of typical eukaryote-like, fungi-like and other bacteria-like class III cyclase sequences within this phylum, suggesting that these proteins may have significant roles to play in this important group of organisms.

  3. PCSK1 rs6232 Is Associated with Childhood and Adult Class III Obesity in the Mexican Population

    Science.gov (United States)

    Villalobos-Comparán, Marisela; Villamil-Ramírez, Hugo; Villarreal-Molina, Teresa; Larrieta-Carrasco, Elena; León-Mimila, Paola; Romero-Hidalgo, Sandra; Jacobo-Albavera, Leonor; Liceaga-Fuentes, Adriana E.; Campos-Pérez, Francisco J.; López-Contreras, Blanca E.; Tusié-Luna, Teresa; del Río-Navarro, Blanca E.; Aguilar-Salinas, Carlos A.; Canizales-Quinteros, Samuel

    2012-01-01

    Background Common variants rs6232 and rs6235 in the PCSK1 gene have been associated with obesity in European populations. We aimed to evaluate the contribution of these variants to obesity and related traits in Mexican children and adults. Methodology/Principal Findings Rs6232 and rs6235 were genotyped in 2382 individuals, 1206 children and 1176 adults. Minor allele frequencies were 0.78% for rs6232 and 19.99% for rs6235. Rs6232 was significantly associated with childhood obesity and adult class III obesity (OR = 3.01 95%CI 1.64–5.53; P = 4×10−4 in the combined analysis). In addition, this SNP was significantly associated with lower fasting glucose levels (P = 0.01) and with increased insulin levels and HOMA-B (P = 0.05 and 0.01, respectively) only in non-obese children. In contrast, rs6235 showed no significant association with obesity or with glucose homeostasis parameters in any group. Conclusion/Significance Although rs6232 is rare in the Mexican population, it should be considered as an important risk factor for extreme forms of obesity. PMID:22737226

  4. More on fatigue verification of Class 1 nuclear power piping according to ASME BPV III NB-3600

    International Nuclear Information System (INIS)

    In this paper, fatigue verification of Class 1 nuclear power piping according to ASME Boiler and Pressure Vessel Code, Section III, NB-3600, and relevant issues that are often discussed in connection to the power uprate of several Swedish BWR reactors in recent years, are dealt with. Key parameters involved in the fatigue verification, i.e. the alternating stress intensity Salt, the penalty factor Ke and the cumulative damage factor U, and relevant computational procedures applicable for the assessment of low-cycle fatigue failure using strain-controlled data, are particularly addressed. A so-called simplified elastic-plastic discontinuity analysis for alternative verification when basic fatigue requirements found unsatisfactory, and the procedures provided in NB-3600 for evaluating the alternating stress intensity Salt, are reviewed in detail. Our emphasis is placed on other procedures alternative to the simplified elastic-plastic discontinuity analysis. A more in-depth discussion is given to an alternative suggested earlier by the authors using nonlinear finite element analyses. This paper is a continuation of our work presented in ICONE16/17/18, which attempted to categorize design rules in the code into linear design rules and non-linear design rules and to clarify corresponding design requirements and finite element analyses, in particular, those non-linear ones. (author)

  5. Biochemical characterization of a recombinant plant class III chitinase from the pitcher of the carnivorous plant Nepenthes alata.

    Science.gov (United States)

    Ishisaki, Kana; Arai, Sachiko; Hamada, Tatsuro; Honda, Yuji

    2012-11-01

    A class III chitinase belonging to the GH18 family from Nepenthes alata (NaCHIT3) was expressed in Escherichia coli. The enzyme exhibited hydrolytic activity toward colloidal chitin, ethylene glycol chitin, and (GlcNAc)(n) (n=5 and 6). The enzyme hydrolyzed the fourth glycosidic linkage from the non-reducing end of (GlcNAc)(6). The anomeric form of the products indicated it was a retaining enzyme. The colloidal chitin hydrolytic reaction displayed high activity between pH 3.9 and 6.9, but the pH optimum of the (GlcNAc)(6) hydrolytic reaction was 3.9 at 37 °C. The optimal temperature for activity was 65 °C in 50 mM sodium acetate buffer (pH 3.9). The pH optima of NaCHIT3 and NaCHIT1 might be related to their roles in chitin degradation in the pitcher fluid. PMID:23026711

  6. SPITZER INFRARED SPECTROGRAPH OBSERVATIONS OF CLASS I/II OBJECTS IN TAURUS: COMPOSITION AND THERMAL HISTORY OF THE CIRCUMSTELLAR ICES

    International Nuclear Information System (INIS)

    We present observations of Taurus-Auriga Class I/II protostars obtained with the Spitzer InfraRed Spectrograph. Detailed spectral fits to the 6 and 15.2 micron ice features are made, using publicly available laboratory data, to constrain the molecular composition, abundances, and levels of thermal processing along the lines of sight. We provide an inventory of the molecular environments observed, which have an average composition dominated by water-ice with ∼12% CO2 (abundance relative to H2O), ∼>2%-9% CH3OH, ∼14% NH3, ∼3% CH4, ∼2% H2CO, ∼0.6% HCOOH, and ∼0.5% SO2. We find CO2/H2O ratios nearly equivalent to those observed in cold clouds and lines of sight toward the galactic center. The unidentified 6.8 micron profiles vary from source to source, and it is shown to be likely that even combinations of the most common candidates (NH+4 and CH3OH) are inadequate to explain the feature fully. We discuss correlations among SED spectral indices, abundance ratios, and thermally processed ice fractions and their implications for CO2 formation and evolution. Comparison of our spectral fits with cold molecular cloud sight lines indicates abundant prestellar ice environments made even richer by the radiative effects of protostars. Our results add additional constraints and a finer level of detail to current full-scale models of protostellar and protoplanetary systems.

  7. Spitzer IRS Observations of Class I/II Objects in Taurus: Composition, Temperature and Thermal History of the Circumstellar Ices

    CERN Document Server

    Zasowski, G; Watson, Dan M; Furlan, E; Bohac, C J; Hull, C; Green, J D

    2007-01-01

    We present observations of Taurus-Auriga Class I/II protostars obtained with the Spitzer InfraRed Spectrograph. Detailed spectral fits to the 6 and 15 micron features are made, using publicly-available laboratory data, to constrain the molecular composition, abundances, and levels of thermal processing along the lines of sight. We provide an inventory of the molecular environments observed, which have an average composition dominated by water ice with ~12% CO_2 (abundance relative to H_2O), >~2-9% CH_3OH, <~14% NH_3, ~4% CH_4, ~2% H_2CO, ~0.6% HCOOH, and ~0.5% SO_2. We find CO_2/H_2O ratios nearly equivalent to those observed in cold clouds and lines of sight toward the galactic center. The unidentified 6.8 micron profile shapes vary from source to source, and it is shown to be likely that even combinations of the most common candidates (NH_4+ and CH_3OH) are inadequate to explain the feature fully. We discuss correlations among SED spectral indices, abundance ratios, and thermally-processed ice fractions ...

  8. Combined Orthodontic and Surgical Approach in the Correction of a Class III Skeletal Malocclusion with Mandibular Prognathism and Vertical Maxillary Excess Using Bimaxillary Osteotomy

    Directory of Open Access Journals (Sweden)

    George Jose Cherackal

    2013-01-01

    Full Text Available For patients whose orthodontic problems are so severe that neither growth modification nor camouflage offers a solution, surgery to realign the jaws or reposition dentoalveolar segments is the only possible treatment. Surgery is not a substitute for orthodontics in these patients. Instead, it must be properly coordinated with orthodontics and other dental treatments to achieve good overall results. Dramatic progress in recent years has made it possible for combined surgical orthodontic treatment to be carried out successfully for patients with a severe dentofacial problem of any type. This case report provides an overview of the current treatment methodology in managing a combination of asymmetrical mandibular prognathism and vertical maxillary excess.

  9. Molecular cloning of class III chitinase gene from Avicennia marina and its expression analysis in response to cadmium and lead stress.

    Science.gov (United States)

    Wang, Li-Ying; Wang, You-Shao; Zhang, Jing-Ping; Gu, Ji-Dong

    2015-10-01

    Mangrove species have high tolerance to heavy metal pollution. Chitinases have been widely reported as defense proteins in response to heavy metal stress in terrestrial plants. In this study, a full-length cDNA sequence encoding an acidic and basic class III chitinase (AmCHI III) was cloned by using RT-PCR and RACE methods in Avicennia marina. AmCHI III mRNA expression in leaf of A. marina were investigated under Cd, Pb stresses on using real-time quantitative PCR. The deduced AmCHI III protein consists of 302 amino acids, including a signal putative peptide region, and a catalytic domain. Homology modeling of the catalytic domain revealed a typical molecular structure of class III plant chitinases. Results further demonstrated that the regulation of AmCHI III mRNA expression in leaves was strongly dependent on Cd, Pb stresses. AmCHI III mRNA expressions were significantly increased in response to Cd, Pb, and peaked at 7 days Cd-exposure, 7 days Pb-exposure, respectively. AmCHI III mRNA expression exhibited more sensitive to Pb stress than Cd stress. This work was the first time cloing chitinase from A. marina, and it brought evidence on chitinase gene involving in heavy metals (Cd(2+) and Pb(2+)) resistance or detoxification in plants. Further studies including the promoter and upstream regulation, gene over-expression and the response of mangrove chitinases to other stresses will shed more light on the role of chitinase in mangrove plants. PMID:26044930

  10. Frontal cephalometric evaluation of transverse dentofacial morphology and growth of children with isolated cleft palate.

    Science.gov (United States)

    Athanasiou, A E; Moyers, R E; Mazaheri, M; Toutountzakis, N

    1991-08-01

    The transverse dentofacial morphology and growth of 64 children operated on for clefting of the hard and soft palate was studied by means of a frontal proportional cephalometric analysis and was compared to a normal sample at the ages 3-4, 8-9 and 12 years. The cross-sectional comparison of the cleft palate and normal samples at the three periods indicated: (a) The presence in the cleft group of significantly increased ratios of the inner orbital width to the interorbital width and of the width of the nasal cavity to the interorbital width; (b) the absence of any significant differences in the ratio of the maxillary intermolar width to the interorbital width; and (c) the presence of almost identical ratios of the intergonial width of the mandible to the interorbital width and of the width of the maxilla to the intergonial width of the mandible. Evaluation of the changes of all cephalometric variables during the period 8-12 years showed the absence of any significant difference between the cleft palate and normal groups. PMID:1939671

  11. Dissatisfaction with dentofacial appearance and the normative need for orthodontic treatment: determinant factors

    Directory of Open Access Journals (Sweden)

    Anderson Barbosa de Almeida

    2014-06-01

    Full Text Available OBJECTIVE: This study aims at assessing the normative need for orthodontic treatment and the factors that determine the subjective impact of malocclusion on 12-year-old Brazilian school children. METHODS: A total of 451 subjects (215 males and 236 females were randomly selected from private and public schools of Juiz de Fora, Brazil. The collected data included sociodemographic information and occlusal conditions. The esthetic subjective impact of malocclusion was assessed by means of the Orthodontic Aesthetic Subjective Impact Score - OASIS, whereas the malocclusion and the need for orthodontic treatment were assessed by means of the Dental Aesthetic Index (DAI and the Index of Orthodontic Treatment Need-Aesthetic Component (IOTN-AC. RESULTS: Prevalence of normative need for orthodontic treatment was 65.6% (n = 155, and prevalence of orthodontic esthetic subjective impact was 14.9%. The following variables showed significant association with esthetic subjective impact of malocclusion: female (p = 0.042; OR = 0.5; CI = 0.2-0.9, public school student (p = 0.002; OR = 6.8; CI = 1.9-23.8, maxillary overjet ≥ 4 mm (p = 0.037; OR = 1.7; CI = 1-3 and gingival smile ≥ 4 mm (p = 0.008; OR = 3.4; CI = 1.3-8.8. CONCLUSION: The normative need for orthodontic treatment overestimated the perceived need. Occlusal and sociocultural factors influenced the dissatisfaction of schoolchildren with their dentofacial appearance.

  12. Oral Health and Dentofacial Anomalies among β-THALASSEMIA Major in Erbil City, Iraq

    Science.gov (United States)

    Saeed, Lamya M.; Majeed, Vian O.

    2010-04-01

    Thalassemias are a heterogeneous group of genetic disorders characterized by hypochromic microcytic anemia that caused by deficient synthesis of one or more of globin subunits of human hemoglobin. This study has been conducted in the Northern part of Iraq among 238 subjects having β-thalassemia major (BTM). To evaluate their oral health status, dentofacial anomalies of patients who attended the Thalassemic center in Erbil city, were compared to 258 subjects of a control group according to the criteria suggested by the WHO in 1997, which is used to assess permanent teeth. Only 8.51% of the total study group demonstrated crowding of anterior teeth in one or both segments compared to the control group. Spacing in the incisal segments was higher, namely 19.23% in BTM compared to13.6% in the control group with a statistically significant difference (pindex = 1.570, ∓0.321 and gingival index = 1.205, ∓0.308). Differences were statistically highly significant for all indices (poral hygiene and dental health.

  13. Pre-arthroplasty simultaneous maxillomandibular distraction osteogenesis for the correction of post-ankylotic dentofacial deformities.

    Science.gov (United States)

    Mehrotra, D; Vishwakarma, K; Chellapa, A L; Mahajan, N

    2016-07-01

    The aim of this study was to evaluate the hard and soft tissue changes after pre-arthroplasty simultaneous maxillomandibular distraction osteogenesis for the correction of post-ankylotic dentofacial deformities. This prospective study included 10 patients with unilateral temporomandibular joint (TMJ) ankylosis who presented with a facial deformity and a maxillary cant. Informed patient consent was obtained for participation. Simultaneous maxillomandibular distraction was planned based on clinical and radiographic examinations. A horizontal mandibular osteotomy was performed in the ramus and the distractor device was fixed. A bilateral Le Fort I osteotomy was then performed and a four-hole straight plate was fixed on the contralateral zygomatic buttress to act as a fulcrum. After a latency period of 5 days, the distractor was activated twice daily by 0.5mm until the required vertical lengthening was achieved. Intermaxillary fixation was maintained during the entire distraction period. After a consolidation period of 8-12 weeks, the distractor was removed. The TMJ ankylosis was released and a temporal fascia interpositional arthroplasty was performed as second surgery, along with a genioplasty if needed. All patients were followed up for a period of 12-24 months. A marked improvement in the facial asymmetry was noted in all cases. The occlusal cant and mandibular retrusion improved satisfactorily, and the average postoperative inter-incisal opening was 35.6mm. Pre-arthroplasty simultaneous maxillomandibular distraction offers a good treatment outcome, as it allows improvements in facial aesthetics as well as function. PMID:26780926

  14. Partial glossectomy as an auxiliary method to orthodontic treatment of dentofacial deformity

    Directory of Open Access Journals (Sweden)

    Salmen, Fued Samir

    2012-01-01

    Full Text Available Introduction: macroglossia is a condition which influences the size and shape of the teeth employed due to the forces on teeth. Objective: To establish bases for the indication of partial glossectomy associated with orthodontic treatment and surgical dento-facial deformity in patients without tumors and Down syndrome as a cause of macroglossia. Case reports: Three patients underwent orthognathic surgery associated with partial glossectomy under general anesthesia. All patients had macroglossia relative and underwent clinical assessment taking into account the respiratory function, swallowing and speech deficits and radiological evaluation. The technique used consist of segmental resection along the median raphe of the tongue and suture by planes. We used rigid skeletal fixation with titanium plates and screws so that patients could stay without intermaxillary block in the immediate postoperative period. Were followed over five years. The symptoms regressed completely and all skeletal segments remained stable. Discussion: The decision to refer the patient to partial glossectomy should be based on the volume of the language, mobility, position, function, symptoms, speech intelligibility, skeletal anterior open bite, interference in orthodontic treatment, drooling, swallowing and tongue trauma applicant.

  15. Class III β-tubulin is a predictive marker for taxane-based chemotherapy in recurrent and metastatic gastric cancer

    International Nuclear Information System (INIS)

    Class III β-tubulin (TUBB3) is a prognostic marker in various tumors, but the role of TUBB3 in advanced gastric cancer is not clearly defined. We analyzed the significance of TUBB3 expression, along with that of excision repair cross-complementation group 1 (ERCC1) in recurrent and metastatic gastric cancer patients receiving taxane-based first-line palliative chemotherapy. We reviewed the cases of 146 patients with advanced gastric adenocarcinoma who received taxane-based first-line palliative chemotherapy between 2004 and 2010 at Chonnam National University Hwasun Hospital (Gwangju, Korea). Immunohistochemical staining for TUBB3 and ERCC1 was performed using paraffin wax-embedded tumor tissues. We evaluated the patients’ response to chemotherapy, progression-free survival (PFS), and overall survival (OS). In total, 146 patients with advanced gastric cancer received docetaxel and cisplatin (n = 15) or paclitaxel and cisplatin (n = 131). The median PFS was significantly shorter for patients with high-level TUBB3 expression than for patients with low-level TUBB3 expression (3.63 vs. 6.67 months, P = 0.001). OS was not associated with TUBB3 expression (13.1 vs. 13.1 months, P = 0.769). By multivariate analysis, only TUBB3 was related to a shorter PFS (HR 2.74, 95% CI 1.91-3.91, P = 0.001). Patients with high-level ERCC1 expression showed a lower response rate than patients with low-level ERCC1 expression (24 vs. 63.2%, P = 0.001); however, ERCC1 had no clinical effect on PFS or OS. TUBB3 was a strong predictive marker in recurrent and metastatic gastric cancer patients receiving taxane-based first-line palliative chemotherapy. No clinical impact of ERCC1 was evident in this setting

  16. Functional characterization of a class III acid endochitinase from the traps of the carnivorous pitcher plant genus, Nepenthes.

    Science.gov (United States)

    Rottloff, Sandy; Stieber, Regina; Maischak, Heiko; Turini, Florian G; Heubl, Günther; Mithöfer, Axel

    2011-08-01

    Carnivory in plants is an adaptation strategy to nutrient-poor environments and soils. Carnivorous plants obtain some additional mineral nutrients by trapping and digesting prey; the genus Nepenthes is helped by its specialized pitcher traps. To make the nutrients available, the caught prey needs to be digested, a process that requires the concerted activity of several hydrolytic enzymes. To identify and investigate the various enzymes involved in this process, fluid from Nepenthes traps has been analysed in detail. In this study, a novel type of Nepenthes endochitinase was identified in the digestion fluid of closed pitchers. The encoding endochitinase genes have been cloned from eight different Nepenthes species. Among these, the deduced amino acid sequence similarity was at least 94.9%. The corresponding cDNA from N. rafflesiana was heterologously expressed, and the purified protein, NrChit1, was biochemically characterized. The enzyme, classified as a class III acid endochitinase belonging to family 18 of the glycoside hydrolases, is secreted into the pitcher fluid very probably due to the presence of an N-terminal signal peptide. Transcriptome analyses using real-time PCR indicated that the presence of prey in the pitcher up-regulates the endochitinase gene not only in the glands, which are responsible for enzyme secretion, but at an even higher level, in the glands' surrounding tissue. These results suggest that in the pitchers' tissues, the endochitinase as well as other proteins from the pitcher fluid might fulfil a different, primary function as pathogenesis-related proteins. PMID:21633084

  17. Reductions in knee joint forces with weight loss are attenuated by gait adaptations in class III obesity.

    Science.gov (United States)

    DeVita, Paul; Rider, Patrick; Hortobágyi, Tibor

    2016-03-01

    A consensus exists that high knee joint forces are a precursor to knee osteoarthritis and weight loss reduces these forces. Because large weight loss also leads to increased step length and walking velocity, knee contact forces may be reduced less than predicted by the magnitude of weight loss. The purpose was to determine the effects of weight loss on knee muscle and joint loads during walking in Class III obese adults. We determined through motion capture, force platform measures and biomechanical modeling the effects of weight loss produced by gastric bypass surgery over one year on knee muscle and joint loads during walking at a standard, controlled velocity and at self-selected walking velocities. Weight loss equaling 412N or 34% of initial body weight reduced maximum knee compressive force by 824N or 67% of initial body weight when walking at the controlled velocity. These changes represent a 2:1 reduction in knee force relative to weight loss when walking velocity is constrained to the baseline value. However, behavioral adaptations including increased stride length and walking velocity in the self-selected velocity condition attenuated this effect by ∼50% leading to a 392N or 32% initial body weight reduction in compressive force in the knee joint. Thus, unconstrained walking elicited approximately 1:1 ratio of reduction in knee force relative to weight loss and is more indicative of walking behavior than the standard velocity condition. In conclusion, massive weight loss produces dramatic reductions in knee forces during walking but when patients stride out and walk faster, these favorable reductions become substantially attenuated. PMID:26979878

  18. Differential regulation of meristem size, morphology and organization by the ERECTA, CLAVATA and class III HD-ZIP pathways.

    Science.gov (United States)

    Mandel, Tali; Candela, Héctor; Landau, Udi; Asis, Lior; Zelinger, Einat; Carles, Cristel C; Williams, Leor Eshed

    2016-05-01

    The shoot apical meristem (SAM) of angiosperm plants is a small, highly organized structure that gives rise to all above-ground organs. The SAM is divided into three functional domains: the central zone (CZ) at the SAM tip harbors the self-renewing pluripotent stem cells and the organizing center, providing daughter cells that are continuously displaced into the interior rib zone (RZ) or the surrounding peripheral zone (PZ), from which organ primordia are initiated. Despite the constant flow of cells from the CZ into the RZ or PZ, and cell recruitment for primordium formation, a stable balance is maintained between the distinct cell populations in the SAM. Here we combined an in-depth phenotypic analysis with a comparative RNA-Seq approach to characterize meristems from selected combinations of clavata3 (clv3), jabba-1D (jba-1D) and erecta (er) mutants of Arabidopsis thaliana We demonstrate that CLV3 restricts meristem expansion along the apical-basal axis, whereas class III HD-ZIP and ER pathways restrict meristem expansion laterally, but in distinct and possibly perpendicular orientations. Our k-means analysis reveals that clv3, jba-1D/+ and er lead to meristem enlargement by affecting different aspects of meristem function; for example, clv3 displays an increase in the stem cell population, whereas jba-1D/+ er exhibits an increase in mitotic activity and in the meristematic cell population. Our analyses demonstrate that a combined genetic and mRNA-Seq comparative approach provides a precise and sensitive method to identify cell type-specific transcriptomes in a small structure, such as the SAM. PMID:26989178

  19. The ERECTA, CLAVATA and class III HD-ZIP Pathways Display Synergistic Interactions in Regulating Floral Meristem Activities.

    Directory of Open Access Journals (Sweden)

    Udi Landau

    Full Text Available In angiosperms, the production of flowers marks the beginning of the reproductive phase. At the emergence of flower primordia on the flanks of the inflorescence meristem, the WUSCHEL (WUS gene, which encodes a homeodomain transcription factor starts to be expressed and establishes de novo stem cell population, founder of the floral meristem (FM. Similarly to the shoot apical meristem a precise spatial and temporal expression pattern of WUS is required and maintained through strict regulation by multiple regulatory inputs to maintain stem cell homeostasis. However, following the formation of a genetically determined fixed number of floral organs, this homeostasis is shifted towards organogenesis and the FM is terminated. In here we performed a genetic study to test how a reduction in ERECTA, CLAVATA and class III HD-ZIP pathways affects floral meristem activity and flower development. We revealed strong synergistic phenotypes of extra flower number, supernumerary whorls, total loss of determinacy and extreme enlargement of the meristem as compared to any double mutant combination indicating that the three pathways, CLV3, ER and HD-ZIPIII distinctively regulate meristem activity and that they act in parallel. Our findings yield several new insights into stem cell-driven development. We demonstrate the crucial requirement for coupling floral meristem termination with carpel formation to ensure successful reproduction in plants. We also show how regulation of meristem size and alternation in spatial structure of the meristem serve as a mechanism to determine flower organogenesis. We propose that the loss of FM determinacy due to the reduction in CLV3, ER and HD-ZIPIII activity is genetically separable from the AGAMOUS core mechanism of meristem termination.

  20. Cell wall-bound cationic and anionic class III isoperoxidases of pea root: biochemical characterization and function in root growth.

    Science.gov (United States)

    Kukavica, Biljana M; Veljovicc-Jovanovicc, Sonja D; Menckhoff, Ljiljana; Lüthje, Sabine

    2012-07-01

    Cell wall isolated from pea roots was used to separate and characterize two fractions possessing class III peroxidase activity: (i) ionically bound proteins and (ii) covalently bound proteins. Modified SDS-PAGE separated peroxidase isoforms by their apparent molecular weights: four bands of 56, 46, 44, and 41kDa were found in the ionically bound fraction (iPOD) and one band (70kDa) was resolved after treatment of the cell wall with cellulase and pectinase (cPOD). Isoelectric focusing (IEF) patterns for iPODs and cPODs were significantly different: five iPODs with highly cationic pI (9.5-9.2) were detected, whereas the nine cPODs were anionic with pI values between pH 3.7 and 5. iPODs and cPODs showed rather specific substrate affinity and different sensitivity to inhibitors, heat, and deglycosylation treatments. Peroxidase and oxidase activities and their IEF patterns for both fractions were determined in different zones along the root and in roots of different ages. New iPODs with pI 9.34 and 9.5 were induced with root growth, while the activity of cPODs was more related to the formation of the cell wall in non-elongating tissue. Treatment with auxin that inhibits root growth led to suppression of iPOD and induction of cPOD. A similar effect was obtained with the widely used elicitor, chitosan, which also induced cPODs with pI 5.3 and 5.7, which may be specifically related to pathogen defence. The differences reported here between biochemical properties of cPOD and iPOD and their differential induction during development and under specific treatments implicate that they are involved in specific and different physiological processes. PMID:22760472

  1. Apresentação de um caso clínico de Classe III de Angle, tratado com o aparelho extrabucal basculante inferior de ação reversa, proposto por Baptista Apresentation of a Angle Class III clinic case, treated with lower headgear of reverse action appliance, suggested by Baptista

    OpenAIRE

    Sylvio Gonçalves Filho; Andrea Chaves; Miguel Neil Benvenga

    2005-01-01

    As más oclusões de Classe III são as de menor incidência em nossas clínicas. Porém, a intervenção precoce têm-se mostrado muito importante para que não haja um agravamento do quadro, influenciando o comportamento psicossocial do paciente. Neste artigo serão demonstrados os resultados com um aparelho muito simples de usar, com boa colaboração dos pacientes e resultados animadores.Early treatment in patients with Class III maloclusion can avoid psychological disordes.The effects of orthopedic t...

  2. Subepithelial Connective Tissue Graft in Combination with a Tunnel Technique for the Treatment of Miller Class II and III Gingival Recessions in Mandibular Incisors: Clinical and Esthetic Results.

    Science.gov (United States)

    Nart, Jose; Valles, Cristina

    2016-01-01

    There is limited evidence regarding the effect of the subepithelial connective tissue graft (SCTG) on root coverage in the mandibular anterior region. A sample of 15 Miller Class II and III recessions were treated in 15 patients using a SCTG with a tunnel technique. After a mean follow-up of 20.53 months, the mean percentage of root coverage was 83.25% for all treated recessions. Furthermore, a statistically significant increase of keratinized tissue was observed at the end of the evaluation period (2.66 mm; P = .001). The combination of tunnel technique and SCTG should be considered a treatment option to obtain root coverage in mandibular incisors with Class II and III recession defects. PMID:27333018

  3. Treatment of skeletal class III malocclusion using face mask therapy with alternate rapid maxillary expansion and constriction (Alt-RAMEC protocol

    Directory of Open Access Journals (Sweden)

    Anand Ramchandra Rathi

    2015-01-01

    Full Text Available Class III malocclusion is very common malocclusion and can be due to maxillary retrusion, mandibular prognathism, or combination. Ellis and McNamara found a combination of maxillary retrusion and mandibular protrusion to be the most common skeletal relationship (30%. The treatment should be carried out as early as possible for permitting normal growth of the skeletal bases. Reverse pull head gear combined with maxillary expansion can effectively correct skeletal Class III malocclusion due to maxillary deficiency in growing patient. An eight-year-old female patient with chief complaint of prognathic mandible and anterior crossbite was successfully treated in duration of 5 months with facemask and expansion therapy based on Alternate Rapid Maxillary Expansion and Constriction (Alt-RAMEC protocol.

  4. Treatment of skeletal class III malocclusion using face mask therapy with alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocol.

    Science.gov (United States)

    Rathi, Anand Ramchandra; Kumari, N Retna; Vadakkepuriyal, Kannan; Santhkumar, Madhu

    2015-01-01

    Class III malocclusion is very common malocclusion and can be due to maxillary retrusion, mandibular prognathism, or combination. Ellis and McNamara found a combination of maxillary retrusion and mandibular protrusion to be the most common skeletal relationship (30%). The treatment should be carried out as early as possible for permitting normal growth of the skeletal bases. Reverse pull head gear combined with maxillary expansion can effectively correct skeletal Class III malocclusion due to maxillary deficiency in growing patient. An eight-year-old female patient with chief complaint of prognathic mandible and anterior crossbite was successfully treated in duration of 5 months with facemask and expansion therapy based on Alternate Rapid Maxillary Expansion and Constriction (Alt-RAMEC) protocol. PMID:26381639

  5. Class III beta-tubulin is constitutively coexpressed with glial fibrillary acidic protein and nestin in midgestational human fetal astrocytes: implications for phenotypic identity

    Czech Academy of Sciences Publication Activity Database

    Dráberová, Eduarda; Del Valle, L.; Gordon, J.; Marková, Vladimíra; Šmejkalová, Barbora; Bertrand, L.; de Chadarévian, J.-P.; Agamanolis, D.P.; Legido, A.; Khalili, K.; Dráber, Pavel; Katsetos, C.D.

    2008-01-01

    Roč. 67, č. 4 (2008), s. 341-354. ISSN 0022-3069 R&D Projects: GA MŠk LC545; GA ČR GA204/05/2375 Institutional research plan: CEZ:AV0Z50520514 Keywords : astrocytes * class III beta-tubulin * fetal glia Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 5.140, year: 2008

  6. Cephalometric analysis of hard and soft tissues in a 12-year-old syndromic child: A case report and update on dentofacial features of Crouzon syndrome

    Directory of Open Access Journals (Sweden)

    K Nagaraju

    2011-01-01

    Full Text Available Crouzon syndrome or craniofacial dysostosis is a rare syndrome characterized by craniosynostosis, midfacial hypoplasia and exophthalmia. The abnormalities found in this syndrome change too much from case to case depending on the suture fusion order. We report a case of a 12 year old child and a mother showing variations in the dentofacial tissues clinically and radiographically. Subsequently, the application of digital software [Dolphin Imaging 11] enabled us to solve out the case as Crouzon syndrome by analyzing the skeletal and soft tissue alterations. An update of the effects of this syndrome on various systems and dentofacial features with emphasis on tooth abnormalities is documented.

  7. Evaluation of cephalometric changes in patients with class III malocclusion in mixed dentition period following face mask therapy and slow maxillary expansion

    Directory of Open Access Journals (Sweden)

    Ahmad Akhondi MS.

    2008-11-01

    Full Text Available "nBackground and Aim: Among different treatments of patients with Class III malocclusion , orthopedic protraction of maxilla has been known as an effective method in mixed dentition period. The aim of this study was to evaluate the cephalometric changes of Cl III patients in mixed dentition period following face mask therapy and slow maxillary expansion. "nMaterials and Methods: This was a before-after study which was conducted on 10 children in mixed dentition period, who had class III malocclusion and maxillary deficiency according to the Stiener and Mc Namara's analysis. The patients were all treated by protraction face mask and slow maxillary expansion. The cephalometric changes of maxilla , mandible and dental relations during the treatment were analyzed by Paired sample T Test. P<0.05 was considered as the level of significant. "nResults: The overjet increasement was 1.7mm. Co. ANS distance improvement was 5.6mm, Ptm.ANS distance increasing was 3mm, and ultimately improvement of Gf.s distance was 1.5mm which were all statistically significant (p<0.05. "nConclusion: Based on the results of this study, face mask therapy with slow maxillary expansion is able to improve the horizotal position of maxilla, in patients with Cl III malocclusion , in mixed dentition period.

  8. TaqMan Probe-Based Real-Time PCR Assay for Detection and Discrimination of Class I, II, and III tfdA Genes in Soils Treated with Phenoxy Acid Herbicides▿ †

    OpenAIRE

    Bælum, Jacob; Jacobsen, Carsten S.

    2009-01-01

    Separate quantification of three classes of tfdA genes was performed using TaqMan quantitative real-time PCR for 13 different soils subsequent to mineralization of three phenoxy acids. Class III tfdA genes were found to be involved in mineralization more often than class I and II tfdA genes.

  9. Aplicações da distração osteogênica na região dentofacial: o estado da arte Dentofacial applications of distraction osteogenesis: the state of the art

    Directory of Open Access Journals (Sweden)

    Jorge Faber

    2005-08-01

    Full Text Available A distração osteogênica é uma forma de engenharia de tecidos na qual a separação gradual de margens ósseas cirurgicamente seccionadas resulta na geração de novo osso, cujo processo geral de regeneração é similar à ossificação intramembranosa. A técnica ganhou muitas aplicações na região dentofacial que variam da movimentação dentária a avanços da mandíbula ou da face média. Esse artigo revisa a literatura sobre o assunto com o objetivo de proporcionar ao ortodontista e ao cirurgião bucomaxilofacial uma abordagem atualizada das características biológicas e clínicas dessa técnica.Distraction osteogenesis is a tissue engineering technique in which the gradual separation of surgically sectioned bone edges results in the generation of new bone. The basic regeneration process is similar to intramembranous ossification. A great number of applications has been found for it in the dentofacial complex, ranging from tooth distraction to midface advancement. This article reviews the literature regarding distraction osteogenesis with the aim of providing the orthodontist and oral surgeon an updated approach to the clinical and biological aspects of this technique.

  10. Association between class III obesity (BMI of 40-59 kg/m2 and mortality: a pooled analysis of 20 prospective studies.

    Directory of Open Access Journals (Sweden)

    Cari M Kitahara

    2014-07-01

    Full Text Available BACKGROUND: The prevalence of class III obesity (body mass index [BMI]≥40 kg/m2 has increased dramatically in several countries and currently affects 6% of adults in the US, with uncertain impact on the risks of illness and death. Using data from a large pooled study, we evaluated the risk of death, overall and due to a wide range of causes, and years of life expectancy lost associated with class III obesity. METHODS AND FINDINGS: In a pooled analysis of 20 prospective studies from the United States, Sweden, and Australia, we estimated sex- and age-adjusted total and cause-specific mortality rates (deaths per 100,000 persons per year and multivariable-adjusted hazard ratios for adults, aged 19-83 y at baseline, classified as obese class III (BMI 40.0-59.9 kg/m2 compared with those classified as normal weight (BMI 18.5-24.9 kg/m2. Participants reporting ever smoking cigarettes or a history of chronic disease (heart disease, cancer, stroke, or emphysema on baseline questionnaires were excluded. Among 9,564 class III obesity participants, mortality rates were 856.0 in men and 663.0 in women during the study period (1976-2009. Among 304,011 normal-weight participants, rates were 346.7 and 280.5 in men and women, respectively. Deaths from heart disease contributed largely to the excess rates in the class III obesity group (rate differences = 238.9 and 132.8 in men and women, respectively, followed by deaths from cancer (rate differences = 36.7 and 62.3 in men and women, respectively and diabetes (rate differences = 51.2 and 29.2 in men and women, respectively. Within the class III obesity range, multivariable-adjusted hazard ratios for total deaths and deaths due to heart disease, cancer, diabetes, nephritis/nephrotic syndrome/nephrosis, chronic lower respiratory disease, and influenza/pneumonia increased with increasing BMI. Compared with normal-weight BMI, a BMI of 40-44.9, 45-49.9, 50-54.9, and 55-59.9 kg/m2 was associated with an

  11. Dentofacial development in long-term survivors of acute lymphoblastic leukemia. A comparison of three treatment modalities

    International Nuclear Information System (INIS)

    Ninety-seven children who were diagnosed with acute lymphoblastic leukemia before 10 years of age and treated with chemotherapy alone, chemotherapy plus 1800-cGy cranial irradiation (RT), or chemotherapy plus 2400-cGy RT were evaluated for effects of therapy on dentofacial development. All patients were seen at least 5 years postdiagnosis. Dental abnormalities were determined from panoramic radiographs, and craniofacial evaluations were made from lateral cephalometric radiographs. Ninety-one (94%) of all patients and 41 (100%) of patients younger than 5 years of age at diagnosis had abnormal dental development. The severity of these abnormalities was greater in children who received treatment before 5 years of age and in those who received RT. Observed dental abnormalities included tooth agenesis, arrested root development, microdontia, and enamel dysplasias. Craniofacial abnormalities occurred in 18 of 20 (90%) of those patients who received chemotherapy plus 2400-cGy RT before 5 years of age. Mean cephalometric values of this group showed significant deficient mandibular development. The results of this study suggest that the severity of dentofacial-developmental abnormalities secondary to antileukemia therapy are related to the age of the patient at the initiation of treatment and the use of cranial RT

  12. Dentofacial development in long-term survivors of acute lymphoblastic leukemia. A comparison of three treatment modalities

    Energy Technology Data Exchange (ETDEWEB)

    Sonis, A.L.; Tarbell, N.; Valachovic, R.W.; Gelber, R.; Schwenn, M.; Sallan, S. (Children' s Hospital, Boston, MA (USA))

    1990-12-15

    Ninety-seven children who were diagnosed with acute lymphoblastic leukemia before 10 years of age and treated with chemotherapy alone, chemotherapy plus 1800-cGy cranial irradiation (RT), or chemotherapy plus 2400-cGy RT were evaluated for effects of therapy on dentofacial development. All patients were seen at least 5 years postdiagnosis. Dental abnormalities were determined from panoramic radiographs, and craniofacial evaluations were made from lateral cephalometric radiographs. Ninety-one (94%) of all patients and 41 (100%) of patients younger than 5 years of age at diagnosis had abnormal dental development. The severity of these abnormalities was greater in children who received treatment before 5 years of age and in those who received RT. Observed dental abnormalities included tooth agenesis, arrested root development, microdontia, and enamel dysplasias. Craniofacial abnormalities occurred in 18 of 20 (90%) of those patients who received chemotherapy plus 2400-cGy RT before 5 years of age. Mean cephalometric values of this group showed significant deficient mandibular development. The results of this study suggest that the severity of dentofacial-developmental abnormalities secondary to antileukemia therapy are related to the age of the patient at the initiation of treatment and the use of cranial RT.

  13. A study of the effectiveness for response to loss of Class IV power of one standby Class III generator operating in a continuous or test cycle mode

    International Nuclear Information System (INIS)

    This paper presents the results of a reliability study that models, evaluates and compares the effectiveness for response to loss of Class 4 power (LOCLIV) of a single available Class 3 standby generator (SG) at an operating CANDU plant. The modelling is based upon operating and licensing considerations at Point Lepreau Generating Station (PLGS) and is applicable to cases where one of its two SG's is out of service for maintenance when a LOCLIV event occurs. The different licensing requirements for two modes of SG operation, either continuous or in a series of successive testing cycles, when the reactor is shut down or operating at power, have been modelled. Techniques have been developed to convolve the modelled probability of occurrence of a LOCLIV at a particular time instant with the probability of successful SG response and Class 3 system reconfiguration from the existing operational state tot he required safety response state. The concepts, techniques and models developed to measure the response to a LOCLIV event by an SG in continuous or cyclic mode of operation are described in this paper. (author). 6 refs., 3 tabs., 10 figs

  14. Crescimento da base craniana nos diferentes tipos faciais nos relacionamentos maxilomandibulares ortopédicos de Classe I, II e III: Parte 2 (Crescimento médio de Ba-Na, CC-Na e CC-Ba Cranial base growth in different facial types in Class I, II and III orthopedic maxillomandibular relationship: Part 2 (Mean growth of Ba-Na, CC-Na and CC-Ba

    Directory of Open Access Journals (Sweden)

    Lucelma Vilela Pieri

    2007-04-01

    Full Text Available OBJETIVO: este estudo retrospectivo avaliou o crescimento médio da base craniana nos diferentes tipos faciais e de relacionamentos maxilomandibulares ortopédicos.METODOLOGIA: uma amostra aleatória de 300 pacientes brasileiros leucodermas (131 do gênero masculino, 169 do gênero feminino, com idade média inicial de 10 anos e 2 meses (dentadura mista e final de 14 anos e 8 meses (segundos molares em oclusão e tempo médio de observação de 4 anos e 5 meses, foi selecionada em uma clínica particular, em São Paulo, Brasil. Havia 118 Classe I, 151 Classe II e 31 Classe III. Todas as 600 radiografias cefalométricas laterais foram obtidas no mesmo aparelho de raios-x. As análises de Ricketts e Schwarz modificadas por Faltin foram usadas. As medidas lineares (Ba-Na, CC-Na e CC-Ba foram feitas manualmente pelo mesmo examinador em T1 e T2. Os relacionamentos foram estudados juntos e separadamente, considerando tipo facial e gênero. O teste t-pareado e ANOVA foram aplicados. RESULTADOS E CONCLUSÕES: o tipo facial retrovertido cresceu significantemente mais em CC-Na na Classe II, sendo a sua correção desfavorável no gênero feminino; com tendência favorável na Classe III e crescimento dentro do esperado na Classe I. O neutrovertido cresceu significantemente mais em CC-Na nas Classes I e II, sendo desfavorável na Classe II; com crescimento eqüitativo de CC-Na e CC-Ba na Classe III e levemente acima do esperado na Classe I. O provertido teve crescimento eqüitativo em todas as Classes, sendo significantemente favorável na Classe II mandibular; com tendência favorável na Classe III e crescimento médio acima do esperado na Classe I.AIM: This retrospective study evaluated the cranial base mean growth in different facial types and orthopedic maxillomandibular relationship. METHODS: A random sample of 300 Brazilian Caucasian patients (131 males, 169 females, initial and final mean age (10 years 2 months-mixed dentition; 14 years 8 months

  15. Cone-Beam Computed Tomography Assessment of Lower Facial Asymmetry in Unilateral Cleft Lip and Palate and Non-Cleft Patients with Class III Skeletal Relationship.

    Directory of Open Access Journals (Sweden)

    Yifan Lin

    Full Text Available To evaluate, using cone-beam computed tomography (CBCT, both the condylar-fossa relationships and the mandibular and condylar asymmetries between unilateral cleft lip and palate (UCLP patients and non-cleft patients with class III skeletal relationship, and to investigate the factors of asymmetry contributing to chin deviation.The UCLP and non-cleft groups consisted of 30 and 40 subjects, respectively, in mixed dentition with class III skeletal relationships. Condylar-fossa relationships and the dimensional and positional asymmetries of the condyles and mandibles were examined using CBCT. Intra-group differences were compared between two sides in both groups using a paired t-test. Furthermore, correlations between each measurement and chin deviation were assessed.It was observed that 90% of UCLP and 67.5% of non-cleft subjects had both condyles centered, and no significant asymmetry was found. The axial angle and the condylar center distances to the midsagittal plane were significantly greater on the cleft side than on the non-cleft side (P=0.001 and P=0.028, respectively and were positively correlated with chin deviation in the UCLP group. Except for a larger gonial angle on the cleft side, the two groups presented with consistent asymmetries showing shorter mandibular bodies and total mandibular lengths on the cleft (deviated side. The average chin deviation was 1.63 mm to the cleft side, and the average absolute chin deviation was significantly greater in the UCLP group than in the non-cleft group (P=0.037.Compared with non-cleft subjects with similar class III skeletal relationships, the subjects with UCLP showed more severe lower facial asymmetry. The subjects with UCLP presented with more asymmetrical positions and rotations of the condyles on axial slices, which were positively correlated with chin deviation.

  16. Application of Advanced Reservoir Characterization, Simulation, and Production Optimization Strategies to Maximize Recovery in Slope and Basin Clastic Reservoirs, West Texas (Delaware Basin), Class III

    Energy Technology Data Exchange (ETDEWEB)

    Dutton, Shirley P.; Flanders, William A.

    2001-11-04

    The objective of this Class III project was demonstrate that reservoir characterization and enhanced oil recovery (EOR) by CO2 flood can increase production from slope and basin clastic reservoirs in sandstones of the Delaware Mountain Group in the Delaware Basin of West Texas and New Mexico. Phase 1 of the project, reservoir characterization, focused on Geraldine Ford and East Ford fields, which are Delaware Mountain Group fields that produce from the upper Bell Canyon Formation (Ramsey sandstone). The demonstration phase of the project was a CO2 flood conducted in East Ford field, which is operated by Orla Petco, Inc., as the East Ford unit.

  17. Primary failure of eruption combined with bilateral transmigration of mandibular canines, transposition, torus palatinus, and class III incisor relationship: A rare case report.

    Science.gov (United States)

    Elhag, Salma Babiker Idris; Abdulghani, Ashraf Sidig Idris

    2015-01-01

    Eruption disorders are numerous varying from delayed to complete failure of eruption. Primary failure of eruption (PFE) is a rare condition that involves arrested eruption of teeth with the absence of local or general contributory factors. Another rare and clinically challenging phenomenon is canine transmigration which is the intra-osseous movement of impacted canines across the midline. This report presents the first case of combined failure of eruption of multiple teeth with bilateral mandibular canine transmigration, transposition of upper canine and the first premolar, torus palatinus, and class III incisor relationship in a 33-year-old asymptomatic and nonsyndromic female patient. PMID:26929701

  18. Relationship of physical activity and weight loss in women with Class II and Class III obesity: Mediation of exercise-induced changes in tension and depression

    OpenAIRE

    Annesi, James J.

    2010-01-01

    El ejercicio físico predice tanto la pérdida de peso como la mejora en el estado de ánimo. Debido al gasto energético mínimo relacionado con el ejercicio en personas obesas y a su pobre estado cardiovascular se sugirió que el cambio en el estado de ánimo inducido por el ejercicio puede mediar la relación de éste con la pérdida de peso. En el presente estudio experimental, mujeres con obesidad de Clase II y III (N = 75) participaron en un programa de ejercicio moderado y educación en nutrición...

  19. Application for Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site - U10c Disposal Site

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Programs

    2010-08-05

    The NTS is located approximately 105 km (65 mi) northwest of Las Vegas, Nevada. NNSA/NSO is the federal lands management authority for the NTS and NSTec is the Management & Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS is posted with signs along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The U10C Disposal Site is located in the northwest corner of Area 9 at the NTS (Figure 1) and is located in a subsidence crater created by two underground nuclear events, one in October 1962 and another in April 1964. The disposal site opened in 1971 for the disposal of rubbish, refuse, pathological waste, asbestos-containing material, and industrial solid waste. A Notice of Intent form to operate the disposal site as a Class II site was submitted to the state of Nevada on January 26, 1994, and was acknowledged in a letter to the DOE on February 8, 1994. It operated as a state of Nevada Class II Solid Waste Disposal Site (SWDS) until it closed on October 5, 1995, for retrofit as a Class III SWDS. The retrofit consisted of the installation of a minimum four-foot compacted soil layer to segregate the different waste types and function as a liner to inhibit leachate and water flow into the lower waste zone. Five neutron monitoring tubes were installed in this layer to monitor possible leachate production and water activity. Upon acceptance of the installed barrier and approval of an Operating Plan by NDEP/BFF, the site reopened in January 1996 as a Class III SWDS for the disposal of industrial solid waste and other inert waste.

  20. Apresentação de um caso clínico de Classe III de Angle, tratado com o aparelho extrabucal basculante inferior de ação reversa, proposto por Baptista Apresentation of a Angle Class III clinic case, treated with lower headgear of reverse action appliance, suggested by Baptista

    Directory of Open Access Journals (Sweden)

    Sylvio Gonçalves Filho

    2005-02-01

    Full Text Available As más oclusões de Classe III são as de menor incidência em nossas clínicas. Porém, a intervenção precoce têm-se mostrado muito importante para que não haja um agravamento do quadro, influenciando o comportamento psicossocial do paciente. Neste artigo serão demonstrados os resultados com um aparelho muito simples de usar, com boa colaboração dos pacientes e resultados animadores.Early treatment in patients with Class III maloclusion can avoid psychological disordes.The effects of orthopedic therapy an mandibular growth with Batista’s reverse arch is showd in this case, indicating that is possible to solve this maloclusion with efficacy.

  1. Two-Stage Mucogingival Surgery with Free Gingival Autograft and Biomend Membrane and Coronally Advanced Flap in Treatment of Class III Millers Recession.

    Science.gov (United States)

    Rath, Avita; Varma, Smrithi; Paul, Renny

    2016-01-01

    Introduction. Gingival recession is an apical shift of the gingival margin with exposure of the root surface. This migration of the marginal tissue leads to esthetic concerns, dentin hypersensitivity, root caries, and cervical wear. It is, paradoxically, a common finding in patients with a high standard of oral hygiene, as well as in periodontally untreated populations with poor oral hygiene. Changing the topography of the marginal soft tissue in order to facilitate plaque control is a common indication for root coverage procedures and forms a major aspect of periodontal plastic surgeries. The regeneration of a new connective tissue attachment to denuded root surface is by allowing the selective coronal regrowth of periodontal ligament cells while excluding the gingival tissues from the root during wound healing by means of a barrier membrane. Case Presentation. This case reports a two-stage surgical technique for treatment of Miller's class III defect using free gingival autograft and type I absorbable collagen membrane (BioMend®, Zimmer Dental, USA)(§). Conclusions. The 6-month follow-up of the case showed a significant increase in attached gingiva suggesting it as a predictable alternative in the treatment of Millers class III defects. PMID:27525131

  2. The class III anti-arrhythmic agent, amiodarone, inhibits voltage-dependent K(+) channels in rabbit coronary arterial smooth muscle cells.

    Science.gov (United States)

    Li, Hongliang; Kim, Han Sol; Kim, Hye Won; Shin, Sung Eun; Jung, Won-Kyo; Ha, Kwon-Soo; Han, Eun-Taek; Hong, Seok-Ho; Firth, Amy L; Bae, Young Min; Choi, Il-Whan; Park, Won Sun

    2016-07-01

    We examined the inhibitory effect of amiodarone, a class III anti-arrhythmic agent, on voltage-dependent K(+) (Kv) currents in freshly isolated rabbit coronary arterial smooth muscle cells, using a whole-cell patch clamp technique. Amiodarone inhibited Kv currents in a concentration-dependent manner, with a half-maximal inhibitory concentration (IC50) value of 3.9 ± 1.44 μM and a Hill coefficient of 0.45 ± 0.14. Amiodarone did not have a significant effect on the steady-state activation of Kv channels, but shifted the inactivation current toward a more negative potential. Application of consecutive pulses progressively augmented the amiodarone-induced Kv channel inhibition. Another class III anti-arrhythmic agent, dofetilide, did not inhibit the Kv current or change the inhibitory effect of amiodarone on Kv channels. Therefore, these results strongly suggest that amiodarone inhibits Kv currents in a concentration- and state-dependent manner. PMID:27030392

  3. Molecular Cloning and Characterization of a Vacuolar Class III Peroxidase Involved in the Metabolism of Anticancer Alkaloids in Catharanthus roseus1[C

    Science.gov (United States)

    Costa, Maria Manuela R.; Hilliou, Frederique; Duarte, Patrícia; Pereira, Luís Gustavo; Almeida, Iolanda; Leech, Mark; Memelink, Johan; Barceló, Alfonso Ros; Sottomayor, Mariana

    2008-01-01

    Catharanthus roseus produces low levels of two dimeric terpenoid indole alkaloids, vinblastine and vincristine, which are widely used in cancer chemotherapy. The dimerization reaction leading to α-3′,4′-anhydrovinblastine is a key regulatory step for the production of the anticancer alkaloids in planta and has potential application in the industrial production of two semisynthetic derivatives also used as anticancer drugs. In this work, we report the cloning, characterization, and subcellular localization of an enzyme with anhydrovinblastine synthase activity identified as the major class III peroxidase present in C. roseus leaves and named CrPrx1. The deduced amino acid sequence corresponds to a polypeptide of 363 amino acids including an N-terminal signal peptide showing the secretory nature of CrPrx1. CrPrx1 has a two-intron structure and is present as a single gene copy. Phylogenetic analysis indicates that CrPrx1 belongs to an evolutionary branch of vacuolar class III peroxidases whose members seem to have been recruited for different functions during evolution. Expression of a green fluorescent protein-CrPrx1 fusion confirmed the vacuolar localization of this peroxidase, the exact subcellular localization of the alkaloid monomeric precursors and dimeric products. Expression data further supports the role of CrPrx1 in α-3′,4′-anhydrovinblastine biosynthesis, indicating the potential of CrPrx1 as a target to increase alkaloid levels in the plant. PMID:18065566

  4. Two-Stage Mucogingival Surgery with Free Gingival Autograft and Biomend Membrane and Coronally Advanced Flap in Treatment of Class III Millers Recession

    Science.gov (United States)

    Paul, Renny

    2016-01-01

    Introduction. Gingival recession is an apical shift of the gingival margin with exposure of the root surface. This migration of the marginal tissue leads to esthetic concerns, dentin hypersensitivity, root caries, and cervical wear. It is, paradoxically, a common finding in patients with a high standard of oral hygiene, as well as in periodontally untreated populations with poor oral hygiene. Changing the topography of the marginal soft tissue in order to facilitate plaque control is a common indication for root coverage procedures and forms a major aspect of periodontal plastic surgeries. The regeneration of a new connective tissue attachment to denuded root surface is by allowing the selective coronal regrowth of periodontal ligament cells while excluding the gingival tissues from the root during wound healing by means of a barrier membrane. Case Presentation. This case reports a two-stage surgical technique for treatment of Miller's class III defect using free gingival autograft and type I absorbable collagen membrane (BioMend®, Zimmer Dental, USA)§. Conclusions. The 6-month follow-up of the case showed a significant increase in attached gingiva suggesting it as a predictable alternative in the treatment of Millers class III defects. PMID:27525131

  5. Orthopedic treatment of Class III malocclusion with rapid maxillary expansion combined with a face mask: a cephalometric assessment of craniofacial growth patterns

    Directory of Open Access Journals (Sweden)

    Daniella Torres Tagawa

    2012-06-01

    Full Text Available OBJECTIVE: The aim of this prospective study was to assess potential changes in the cephalometric craniofacial growth pattern of 17 children presenting Angle Class III malocclusion treated with a Haas-type expander combined with a face mask. METHODS: Lateral cephalometric radiographs were taken at beginning (T1 and immediately after removal of the appliances (T2, average of 11 months of treatment. Linear and angular measurements were used to evaluate the cranial base, dentoskeletal changes and facial growth pattern. RESULTS: The length of the anterior cranial base experienced a reduction while the posterior cranial base assumed a more vertical position at T1. Some maxillary movement occurred, there was no rotation of the palatal plane, there was a slight clockwise rotation of the mandible, although not significant. The ANB angle increased, thereby improving the relationship between the jaws; dentoalveolar compensation was more evident in the lower incisors. Five out of 12 cases (29.41% showed the following changes: In one case the pattern became more horizontal and in four cases more vertical. CONCLUSIONS: It was concluded after a short-term assessment that treatment with rapid maxillary expansion (RME associated with a face mask was effective in the correction of Class III malocclusion despite the changes in facial growth pattern observed in a few cases.

  6. The effect of implant placement in patients with either Kennedy class II and III on oral health-related quality of life: a prospective clinical trial.

    Science.gov (United States)

    van Eekeren, P J A; Aartman, I H A; Tahmaseb, A; Wismeijer, D

    2016-04-01

    There is little evidence of the effect of implants restored with fixed partial dentures on oral health-related quality of life (OHRQoL) in partially edentulous Kennedy class II and III patients. The aim of this study was to determine the change in OHRQoL in Kennedy classification II and III patients treated with a two-implant-supported fixed dental prosthesis (FDP). Kennedy class II and III patients received dental implants and an FDP. Oral health-related quality of life was measured by administration of the Oral Health Impact Profile-14 (OHIP-14NL) questionnaire at intake (T1), 2 weeks after surgery (T2) and after 1 year of loading (T3). The mean OHIP score at T1 was 6·5 ± 1·2, 2·4 ± 1·0 at T2, and 0·9 ± 0·3 at T3. There was a statistically significant difference between T1 and T2 (P = 0·002) and T1 and T3 (P < 0·001) but not between T2 and T3 (P = 0·407). The OHIP score in Kennedy II patients decreased from 4·8 ± 3·2 at T1 to 1·5 ± 2·0 at T2 and 1·1 ± 1·8 at T3, and that in Kennedy III patients decreased from 8·9 ± 9·6 at T1 to 3·6 ± 8·9 at T2 and 0·8 ± 2·2 at T3. There were no statistically significant differences in the reductions in Kennedy II and III patients. Oral health-related quality of life changed positively in patients treated with implants and an FDP in both groups. There was no change in OHRQoL between the times of implant placement and FDP placement. PMID:26599422

  7. Relationship of physical activity and weight loss in women with Class II and Class III obesity: Mediation of exercise-induced changes in tension and depression

    Directory of Open Access Journals (Sweden)

    James J. Annesi

    2010-01-01

    Full Text Available El ejercicio físico predice tanto la pérdida de peso como la mejora en el estado de ánimo. Debido al gasto energético mínimo relacionado con el ejercicio en personas obesas y a su pobre estado cardiovascular se sugirió que el cambio en el estado de ánimo inducido por el ejercicio puede mediar la relación de éste con la pérdida de peso. En el presente estudio experimental, mujeres con obesidad de Clase II y III (N = 75 participaron en un programa de ejercicio moderado y educación en nutrición durante 24 semanas en centros de la Asociación Cristiana de Jóvenes (YMCA en el sudeste de Estados Unidos. Tal como se esperaba, la participación en las sesiones de ejercicio se relacionó con la pérdida de peso (¿ = -.47, pero, de forma directa, representaron solamente un 17% de la pérdida de peso. Utilizando la aproximación de Baron y Kenny, se encontró una mediación parcial significativa para los cambios en 24 semanas en las puntuaciones de tensión y depresión. Esto sugiere que el ejercicio afectó indirectamente al cambio de peso mediante vías psicológicas y apoyó los principios de la teoría social cognitiva. Después de la replicación, los resultados pueden ayudar a mejorar las teorías explicativas y los tratamientos de control de peso.

  8. Characteristics and prevalence within serogroup O4 of a J96-like clonal group of uropathogenic Escherichia coli O4:H5 containing the class I and class III alleles of papG.

    Science.gov (United States)

    Johnson, J R; Stapleton, A E; Russo, T A; Scheutz, F; Brown, J J; Maslow, J N

    1997-01-01

    The recent discovery of a geographically dispersed clonal group of Escherichia coli O4:H5 that includes prototypic uropathogenic strain J96 prompted us to determine the prevalence of J96-like strains within serogroup O4 and to further assess the characteristics of such strains. We used O:K:H;F serotyping, PCR-based genomic fingerprinting, pulsed-field gel electrophoresis (PFGE), multilocus enzyme electrophoresis (MLEE), and PCR detection of the three papG alleles and of the cytotoxic necrotizing factor 1 (cnf1) and aerobactin (aer) gene sequences to characterize the 15 O4 strains among 336 E. coli isolates from three clinical collections (187 from mixed-source bacteremia, 75 from urosepsis, and 74 from acute cystitis). J96-like strains constituted approximately half of the O4 strains, or 2% of the total population. In contrast to other O4 strains, the J96-like strains characteristically exhibited specific group III capsular antigens, the H5 flagellar and F13 fimbrial antigens, a distinctive PCR genomic fingerprint, the class III papG allele (plus, in 50% of strains, the enigmatic class I papG allele), and cnf1 but lacked aer. A subset of these strains was remarkably homogeneous with respect to all these characteristics and exhibited a distinctive PFGE fingerprint and MLEE pattern. These findings clarify the epidemiological relevance of J96 as a model extraintestinal pathogen, provide further evidence of the class I papG allele outside of strain J96, and offer insights into the evolution of E. coli serogroup O4. PMID:9169745

  9. Small scale application of stable isotopes 18O and deuterium to delineate migration pathways at a Class III landfill site

    International Nuclear Information System (INIS)

    Groundwater beneath a Class Ill landfill situated between two overland flow wastewater treatment operations within a 2.5 mi2 area was characterized with respect to the stable isotopes of water. The isotope ratios obtained were combined with chemical, geologic, and piezometric data to interpret patterns of mixing and flow. This inexpensive method proved to be useful in differentiating different source waters from background groundwater, and provided information useful for determining probable contaminant sources

  10. Effects of lifestyle interventions that include a physical activity component in class II and III obese individuals: a systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Aurélie Baillot

    Full Text Available In class II and III obese individuals, lifestyle intervention is the first step to achieve weight loss and treat obesity-related comorbidities before considering bariatric surgery. A systematic review, meta-analysis, and meta-regression were performed to assess the impact of lifestyle interventions incorporating a physical activity (PA component on health outcomes of class II and III obese individuals.An electronic search was conducted in 4 databases (Medline, Scopus, CINAHL and Sportdiscus. Two independent investigators selected original studies assessing the impact of lifestyle interventions with PA components on anthropometric parameters, cardiometabolic risk factors (fat mass, blood pressure, lipid and glucose metabolism, behaviour modification (PA and nutritional changes, and quality of life in adults with body mass index (BMI ≥ 35 kg/m2. Estimates were pooled using a random-effect model (DerSimonian and Laird method. Heterogeneity between studies was assessed by the Cochran's chi-square test and quantified through an estimation of the I².Of the 3,170 identified articles, 56 met our eligibility criteria, with a large majority of uncontrolled studies (80%. The meta-analysis based on uncontrolled studies showed significant heterogeneity among all included studies. The pooled mean difference in weight loss was 8.9 kg (95% CI, 10.2-7.7; p < 0.01 and 2.8 kg/m² in BMI loss (95% CI, 3.4-2.2; p < 0.01. Long-term interventions produced superior weight loss (11.3 kg compared to short-term (7.2 kg and intermediate-term (8.0 kg interventions. A significant global effect of lifestyle intervention on fat mass, waist circumference, blood pressure, total cholesterol, LDL-C, triglycerides and fasting insulin was found (p<0.01, without significant effect on HDL-C and fasting blood glucose.Lifestyle interventions incorporating a PA component can improve weight and various cardiometabolic risk factors in class II and III obese individuals. However, further

  11. Justicidin A-induced autophagy flux enhances apoptosis of human colorectal cancer cells via class III PI3K and Atg5 pathway.

    Science.gov (United States)

    Won, Shen-Jeu; Yen, Cheng-Hsin; Liu, Hsiao-Sheng; Wu, Shan-Ying; Lan, Sheng-Hui; Jiang-Shieh, Ya-Fen; Lin, Chun-Nan; Su, Chun-Li

    2015-04-01

    Our previous reports showed that justicidin A (JA), a novel and pure arylnaphthalide lignan isolated from Justicia procumbens, induces apoptosis of human colorectal cancer cells and hepatocellular carcinoma cells, leading to the suppression of both tumor cell growth in NOD-SCID mice. Here, we reveal that JA induces autophagy in human colorectal cancer HT-29 cells by conversion of autophagic marker LC3-I to LC3-II. Furthermore, LC3 puncta and autophagic vesicle formation, and SQSTM1/p62 suppression were observed. Administration of autophagy inhibitor (bafilomycin A1 and chloroquine) and transfection of a tandem fluorescent-tagged LC3 (mRFP-GFP) reporter plasmid (ptfLC3) demonstrated that JA induces autophagy flux in HT-29 cells. Expression of LC3, SQSTM1, Beclin 1, and nuclear DNA double-strand breaks (representing apoptosis) were also detected in the tumor tissue of HT-29 cells transplanted into NOD-SCID mice orally administrated with JA. In addition, the expression of autophagy signaling pathway-related molecules p-PDK1, p-mTOR, p-p70S6k/p-RPS6KB2 was decreased, whereas that of class III PI3K, Beclin 1, Atg5-Atg12, and mitochondrial BNIP3 was increased in response to JA. Pre-treatment of the cells with class III PI3K inhibitor 3-methyladenine or Atg5 shRNA attenuated JA-induced LC3-II expression and LC3 puncta formation, indicating the involvement of class III PI3K and Atg5. A novel mechanism was demonstrated in the anticancer compound JA; pre-treatment with 3-methyladenine or Atg5 shRNA blocked JA-induced suppression in cell growth and colony formation, respectively, via inhibition of apoptosis. In contrast, administration of apoptosis inhibitor Z-VAD did not affect JA-induced autophagy. Our data suggest the chemotherapeutic potential of JA for treatment of human colorectal cancer. PMID:25216025

  12. Study on Tensile Fatigue Behavior of Thermal Butt Fusion in Safety Class III High-Density Polyethylene Buried Piping in Nuclear Power Plants

    International Nuclear Information System (INIS)

    High-density polyethylene (HDPE) piping, which has recently been applied to safety class III piping in nuclear power plants, can be butt-joined through the thermal fusion process, which heats two fused surfaces and then subject to axial pressure. The thermal fusion process generates bead shapes on the butt fusion. The stress concentrations caused by the bead shapes may reduce the fatigue lifetime. Thus, investigating the effect of the thermal butt fusion beads on fatigue behavior is necessary. This study examined the fatigue behavior of thermal butt fusion via a tensile fatigue test under stress-controlled conditions using finite element elastic stress analysis. Based on the results, the presence of thermal butt fusion beads was confirmed to reduce the fatigue lifetime in the low-cycle fatigue region while having a negligible effect in the medium- and high-cycle fatigue regions

  13. Heart-cutting two-dimensional liquid chromatography methods for quantification of 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole in Class III caramel colours.

    Science.gov (United States)

    Moretton, Cédric; Crétier, Gérard; Nigay, Henri; Rocca, Jean-Louis

    2008-07-11

    Heart-cutting two-dimensional liquid chromatography/UV detection methods were developed to determine 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole (noted as THI) in Class III caramel colours. In the first dimension, the caramel sample diluted in water was fractionated either by reversed-phase chromatography on C18 silica packing or by ion-exchange chromatography using strong cationic exchanger (SCX) stationary phase. In each case, THI elution domain was recovered in a loop and transferred to a second column packed with porous graphitic carbon (PGC) for the selective separation of THI. From the accuracy profiles with acceptance limit fixed at 20% and beta-expectation tolerance interval fixed at 90%, the two methods, C18-PGC and SCX-PGC, were validated for THI/caramel ratios included between 5-50 and 10-50 ppm, respectively. Finally, the two methods were compared for the analysis of numerous caramel samples. PMID:18538331

  14. Study on Tensile Fatigue Behavior of Thermal Butt Fusion in Safety Class III High-Density Polyethylene Buried Piping in Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jong Sung; Lee, Young Ju [Sunchon National University, Suncheon (Korea, Republic of); Oh, Young Jin [KEPCO E and C, Yongin (Korea, Republic of)

    2015-01-15

    High-density polyethylene (HDPE) piping, which has recently been applied to safety class III piping in nuclear power plants, can be butt-joined through the thermal fusion process, which heats two fused surfaces and then subject to axial pressure. The thermal fusion process generates bead shapes on the butt fusion. The stress concentrations caused by the bead shapes may reduce the fatigue lifetime. Thus, investigating the effect of the thermal butt fusion beads on fatigue behavior is necessary. This study examined the fatigue behavior of thermal butt fusion via a tensile fatigue test under stress-controlled conditions using finite element elastic stress analysis. Based on the results, the presence of thermal butt fusion beads was confirmed to reduce the fatigue lifetime in the low-cycle fatigue region while having a negligible effect in the medium- and high-cycle fatigue regions.

  15. BtcA, A class IA type III chaperone, interacts with the BteA N-terminal domain through a globular/non-globular mechanism.

    Directory of Open Access Journals (Sweden)

    Chen Guttman

    Full Text Available Bordetella pertussis, the etiological agent of "whooping cough" disease, utilizes the type III secretion system (T3SS to deliver a 69 kDa cytotoxic effector protein, BteA, directly into the host cells. As with other T3SS effectors, prior to its secretion BteA binds BtcA, a 13.9 kDa protein predicted to act as a T3SS class IA chaperone. While this interaction had been characterized for such effector-chaperone pairs in other pathogens, it has yet to be fully investigated in Bordetella. Here we provide the first biochemical proof that BtcA is indeed a class IA chaperone, responsible for the binding of BteA's N-terminal domain. We bring forth extensive evidence that BtcA binds its substrate effector through a dual-interface binding mechanism comprising of non-globular and bi-globular interactions at a moderate micromolar level binding affinity. We demonstrate that the non-globular interactions involve the first 31 N-terminal residues of BteA287 and their removal leads to destabilization of the effector-chaperone complex and lower binding affinities to BtcA. These findings represent an important first step towards a molecular understanding of BteA secretion and cell entry.

  16. Crescimento da base craniana nos diferentes tipos faciais nos relacionamentos maxilomandibulares ortopédicos de Classe I, II e III: parte 1 Cranial base growth in different facial types in Class I, II and III orthopedic maxillomandibular relationship: part 1

    OpenAIRE

    Lucelma Vilela Pieri; Kurt Faltin Junior; Cristina Lúcia Feijó Ortolani; Rolf Marçon Faltin; Márcia Aparecida Alves de Almeida

    2007-01-01

    OBJETIVO: este estudo retrospectivo avaliou o crescimento médio anual da base craniana nos diferentes tipos faciais nos relacionamentos maxilomandibulares ortopédicos de Classe I, II e III. METODOLOGIA: uma amostra aleatória de 300 pacientes brasileiros leucodermas (131 do gênero masculino, 169 do gênero feminino), com idade média inicial de 10 anos e 2 meses (dentadura mista) e final de 14 anos e 8 meses (segundos molares em oclusão) e tempo médio de observação de 4 anos e 5 meses, foi selec...

  17. Crescimento da base craniana nos diferentes tipos faciais nos relacionamentos maxilomandibulares ortopédicos de Classe I, II e III: parte 3 (Crescimento médio de CF-Po) Cranial base growth in different facial types in Class I, II and III orthopedic maxillomandibular relationship: part 3 (Mean growth of CF-Po)

    OpenAIRE

    Lucelma Vilela Pieri; Kurt Faltin Junior; Cristina Lúcia Feijó Ortolani; Rolf Marçon Faltin; Márcia Aparecida Alves de Almeida

    2007-01-01

    OBJETIVO: este estudo retrospectivo avaliou o crescimento médio de CF-Po nos diferentes tipos faciais nos relacionamentos maxilomandibulares ortopédicos de Classe I, II e III. METODOLOGIA: uma amostra aleatória de 300 pacientes brasileiros leucodermas (131 do gênero masculino, 169 do gênero feminino), com idade média inicial de 10 anos e 2 meses (dentadura mista) e final de 14 anos e 8 meses (segundos molares em oclusão) e tempo médio de observação de 4 anos e 5 meses, foi selecionada em uma ...

  18. Class I malocclusion with anterior crossbite and severe crowding

    Directory of Open Access Journals (Sweden)

    Daltro Enéas Ritter

    2014-04-01

    Full Text Available This article reports the orthodontic diagnosis and treatment planning carried out with a 14-year and 5-month-old female patient with esthetic and functional complaints. She presented an Angle Class I malocclusion, anterior crossbite and severe crowding in both maxillary and mandibular arches, in addition to a lightly concave straight facial profile. Orthodontic treatment did not require extraction. Crossbite was corrected by protrusion of upper teeth, which contributed to alignment and leveling of teeth, in addition to improving the patient's facial profile. The case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO as a requirement for the BBO certification.

  19. A method for establishing class III medical device equivalence: sodium hyaluronate (GenVisc 850 for the treatment of knee osteoarthritis

    Directory of Open Access Journals (Sweden)

    Doros G

    2016-07-01

    Full Text Available Gheorghe Doros,1 Philip T Lavin,2 Michael Daley,3 Larry E Miller4 1School of Public Health, Boston University, Boston, 2Lavin Consulting LLC, Framingham, MA, 3OrthogenRx Inc., Doylestown, PA, 4Miller Scientific Consulting, Inc., Asheville, NC, USA Abstract: Although the concept of equivalence for drugs (generics and biologics (biosimilars has been readily adopted, the concept of equivalence or indistinguishable characteristics for class III medical devices has yet to be specifically addressed regarding a defined regulatory approval process in the US. In September 2015, GenVisc 850® (sodium hyaluronate, a hyaluronic acid approved for the treatment of knee osteoarthritis, was approved by the US Food and Drug Administration (FDA based upon indistinguishable characteristics in comparison to an approved branded hyaluronic acid (Supartz®/Supartz FX™. The purpose of this paper is to review the methodology and report the main outcomes used to demonstrate clinical comparability of GenVisc 850 with Supartz/Supartz FX. The FDA approval was collectively attained using prospectively defined methods for preclinical, physical, and chemical testing, as well as noninferiority in clinical performance comparisons. Evidence from five randomized controlled studies of Supartz/Supartz FX vs saline control injections (used for Supartz approval, two randomized controlled trials of GenVisc 850 vs saline control injections, and one randomized controlled study of GenVisc 850 vs Supartz/Supartz FX provided evidence of safety for GenVisc 850. Efficacy was further assessed based on assessment of the same Supartz studies and three prospectively identified GenVisc 850 studies. A Bayesian network meta-analysis was used to demonstrate that the clinical efficacy of GenVisc 850 was noninferior to Supartz/Supartz FX and superior to saline control. Overall, safety of GenVisc 850 was similar to that of Supartz/Supartz FX and saline control injections, while efficacy of GenVisc 850

  20. A Cephalometric Study on the Relationship between the Occlusal Plane, Ala-Tragus and Camper’s Lines, in Patients with Angle’s Class III Malocclusion

    Directory of Open Access Journals (Sweden)

    F. Rostamkhani

    2005-06-01

    Full Text Available Statement of Problem: Considering the importance of the occlusal plane orientation in complete denture prostheses, a study was conducted on the relationship between this plane with ala-tragus and Camper’s lines in soft tissue among individuals with class IIImalocclusion, in Mashhad School of Dentistry.Purpose: The aim of the present study was to define the best soft tissue index by which the location and inclination of the occlusal plane in complete dentures could be established.Materials and methods: The participants consisted of 13 males with Angle’s class III occlusal relationship. Radiopaque markers were attached to the intended points on soft tissue and then standard lateral cephalograms were obtained from each subject.The angles between the following lines were measured: Occlusal line (OL, Camper's line (ala-porion, AT1 (ala-superior border of tragus, AT2 (ala- mid-tragus and AT3 (ala-inferior border of tragus.Results: The mean values and standard deviations calculated from the measured variables are as follows: OL-^AT1, 5.65 (3.95 degrees; OL- ^AT2, 3.19 (2.45 degrees;OL- ^AT3, 2.92 (2.42 degrees and OL- ^Camper, 8.5 (3.83 degrees. Comparison of the results by the ANOVA test exhibited a significant difference (F=3.7, P=0.05. Asthe OL^-AT3 angle had the lowest value, the occlusal line had a stronger tendency to be parallel to the AT3 line.Conclusion: According to the present study, the inferior border of the tragus is suggested as the posterior point for ala-tragus line orientation.

  1. Ion pairing with bile salts modulates intestinal permeability and contributes to food-drug interaction of BCS class III compound trospium chloride.

    Science.gov (United States)

    Heinen, Christian A; Reuss, Stefan; Amidon, Gordon L; Langguth, Peter

    2013-11-01

    In the current study the involvement of ion pair formation between bile salts and trospium chloride (TC), a positively charged Biopharmaceutical Classification System (BCS) class III substance, showing a decrease in bioavailability upon coadministration with food (negative food effect) was investigated. Isothermal titration calorimetry provided evidence of a reaction between TC and bile acids. An effect of ion pair formation on the apparent partition coefficient (APC) was examined using (3)H-trospium. The addition of bovine bile and bile extract porcine led to a significant increase of the APC. In vitro permeability studies of trospium were performed across Caco-2-monolayers and excised segments of rat jejunum in a modified Ussing chamber. The addition of bile acids led to an increase of trospium permeation across Caco-2-monolayers and rat excised segments by approximately a factor of 1.5. The addition of glycochenodeoxycholate (GCDC) was less effective than taurodeoxycholate (TDOC). In the presence of an olive oil emulsion, a complete extinction of the permeation increasing effects of bile salts was observed. Thus, although there are more bile acids in the intestine in the fed state compared to the fasted state, these are not able to form ion pairs with trospium in fed state, because they are involved in the emulsification of dietary fats. In conclusion, the formation of ion pairs between trospium and bile acids can partially explain its negative food effect. Our results are presumably transferable to other organic cations showing a negative food effect. PMID:23750707

  2. The Composition of Metals Bound to Class III Metallothionein (Phytochelatin and Its Desglycyl Peptide) Induced by Various Metals in Root Cultures of Rubia tinctorum.

    Science.gov (United States)

    Maitani, T.; Kubota, H.; Sato, K.; Yamada, T.

    1996-04-01

    The induction of phytochelatins (PCs) and their desglycyl peptides (both are referred to as class III metallothionein [CIIIMT]) by exposure to various metals (Ag+, As3+, As5+, Cd2+, Cu2+, Ga3+, Hg2+, In3+, Ni2+, Pb2+, Pd2+, Se4+, and Zn2+) and the metal composition in the CIIIMTs were investigated in root cultures of Rubia tinctorum L. All of these metal species induced PCs to various degrees when analyzed by the postcolumn derivatization high-performance liquid chromatography method. The desglycyl peptides of PCs often were also present. However, only Ag, Cd, and Cu were bound to the CIIIMTs that they induced when analyzed by the high-performance liquid chromatography-inductively coupled plasma-atomic emission spectrometry method. Cu was also bound to the CIIIMTs induced by Ag+, As3+, and Cd2+. After Ag+ exposure, an Fe peak that may be of Fe-CIIIMT was also observed. However, most of the metal species studied were not bound to the CIIIMTs that they induced. PMID:12226248

  3. The Use of Invisalign® System in the Management of the Orthodontic Treatment before and after Class III Surgical Approach

    Science.gov (United States)

    2016-01-01

    The approach to skeletal dysmorphisms in the maxillofacial area usually requires an orthodontic treatment by means of fixed appliances, both before and after the surgical phase. Since its introduction, Invisalign system has become a popular treatment choice for the clinicians because of the aesthetics and comfort of the removable clear aligners compared with the traditional appliances. Therefore, the aim of the present report was to illustrate the management of a malocclusion by means of Invisalign system associated with the traditional surgical technique. The present paper shows a case of a 23-year-old male patient characterized by a Class III malocclusion with lateral deviation of the mandible to the left side and cross-bite on teeth 2.2, 2.3, and 2.4. Invisalign system was used during the pre- and postsurgical phases rather than fixed appliances. The posttreatment cephalometric analysis emphasized the stability of the dental and skeletal symmetry corrections, occlusion and functional balance, over a 6-year follow-up. The results achieved at the end of the treatment showed how Invisalign can be effective in the management of the orthodontic phases in orthognathic surgery. The follow-up after 6 years emphasizes the stability of the treatment over time. PMID:27429811

  4. 骨性错(牙合)患者颌面部美观的自我评价%Self-evaluation of dentofacial esthetics in skeletal malocclusion patients

    Institute of Scientific and Technical Information of China (English)

    孙伟; 侯敏; 王建国

    2013-01-01

    ) and prominence of their teeth (17.8 %) were the most frequent causes of concern.Older subjects,women,and skeletal malocclusion patients were less happy with their facial appearance.Most of them were dissatisfied with the facial appearance focused on the chin (53 %),facial contours (37 %),and the position of the teeth when smiling (33 %).A greater proportion of Class Ⅲ subjects than Class Ⅱ subjects wished to change their appearance.Conclusions The findings indicate that women and skeletal malocclusion patients have lower levels of happiness with their dentofacial appearance.Although Class Ⅱ patients exhibit the lowest levels of happiness with their dental appearance,there is some evidence that concerns and awareness about their facial profile are more pronounced among the Class Ⅲ patients.

  5. Application for a Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site Area 5 Asbestiform Low-Level Solid Waste Disposal Site

    International Nuclear Information System (INIS)

    The NTS solid waste disposal sites must be permitted by the state of Nevada Solid Waste Management Authority (SWMA). The SWMA for the NTS is the Nevada Division of Environmental Protection, Bureau of Federal Facilities (NDEP/BFF). The U.S. Department of Energy's National Nuclear Security Administration Nevada Site Office (NNSA/NSO) as land manager (owner), and National Security Technologies (NSTec), as operator, will store, collect, process, and dispose all solid waste by means that do not create a health hazard, a public nuisance, or cause impairment of the environment. NTS disposal sites will not be included in the Nye County Solid Waste Management Plan. The NTS is located approximately 105 kilometers (km) (65 miles (mi)) northwest of Las Vegas, Nevada (Figure 1). The U.S. Department of Energy (DOE) is the federal lands management authority for the NTS, and NSTec is the Management and Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS has signs posted along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The Area 5 RWMS is the location of the permitted facility for the Solid Waste Disposal Site (SWDS). The Area 5 RWMS is located near the eastern edge of the NTS (Figure 2), approximately 26 km (16 mi) north of Mercury, Nevada. The Area 5 RWMS is used for the disposal of low-level waste (LLW) and mixed low-level waste. Many areas surrounding the RWMS have been used in conducting nuclear tests. A Notice of Intent to operate the disposal site as a Class III site was submitted to the state of Nevada on January 28, 1994, and was acknowledged as being received in a letter to the NNSA/NSO on August 30, 1994. Interim approval to operate a Class III SWDS for regulated asbestiform low-level waste (ALLW) was authorized on August 12, 1996 (in letter from Paul Liebendorfer to Runore Wycoff), with operations to be conducted in accordance with the ''Management Plan

  6. Application for a Permit to Operate a Class III Solid Waste Disposal Site at the Nevada Test Site Area 5 Asbestiform Low-Level Solid Waste Disposal Site

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Programs

    2010-09-14

    The NTS solid waste disposal sites must be permitted by the state of Nevada Solid Waste Management Authority (SWMA). The SWMA for the NTS is the Nevada Division of Environmental Protection, Bureau of Federal Facilities (NDEP/BFF). The U.S. Department of Energy's National Nuclear Security Administration Nevada Site Office (NNSA/NSO) as land manager (owner), and National Security Technologies (NSTec), as operator, will store, collect, process, and dispose all solid waste by means that do not create a health hazard, a public nuisance, or cause impairment of the environment. NTS disposal sites will not be included in the Nye County Solid Waste Management Plan. The NTS is located approximately 105 kilometers (km) (65 miles [mi]) northwest of Las Vegas, Nevada (Figure 1). The U.S. Department of Energy (DOE) is the federal lands management authority for the NTS, and NSTec is the Management and Operations contractor. Access on and off the NTS is tightly controlled, restricted, and guarded on a 24-hour basis. The NTS has signs posted along its entire perimeter. NSTec is the operator of all solid waste disposal sites on the NTS. The Area 5 RWMS is the location of the permitted facility for the Solid Waste Disposal Site (SWDS). The Area 5 RWMS is located near the eastern edge of the NTS (Figure 2), approximately 26 km (16 mi) north of Mercury, Nevada. The Area 5 RWMS is used for the disposal of low-level waste (LLW) and mixed low-level waste. Many areas surrounding the RWMS have been used in conducting nuclear tests. A Notice of Intent to operate the disposal site as a Class III site was submitted to the state of Nevada on January 28, 1994, and was acknowledged as being received in a letter to the NNSA/NSO on August 30, 1994. Interim approval to operate a Class III SWDS for regulated asbestiform low-level waste (ALLW) was authorized on August 12, 1996 (in letter from Paul Liebendorfer to Runore Wycoff), with operations to be conducted in accordance with the &apos

  7. Analysis of HLA class I-II haplotype frequency and segregation in a cohort of patients with advanced stage ovarian cancer.

    Science.gov (United States)

    Gamzatova, Z; Villabona, L; van der Zanden, H; Haasnoot, G W; Andersson, E; Kiessling, R; Seliger, B; Kanter, L; Dalianis, T; Bergfeldt, K; Masucci, G V

    2007-09-01

    In solid tumors, human leucocyte antigen (HLA)-A2 has been suggested to be a risk factor and a negative prognostic factor. The HLA-A2 allele in Scandinavia has a high prevalence; it decreases with latitude and also with ovarian cancer mortality in Europe. Furthermore, an association of the HLA-A2 allele with severe prognosis in serous adenocarcinoma of the ovary in stages III-IV was found. Thirty-two unrelated Swedish women with relapsing or progressive ovarian cancer were analysed for the genotypes at the HLA-A, HLA-B, HLA-Cw, and HLA-DRB1 loci by the polymerase chain reaction/sequence-specific primer method. The frequencies of HLA alleles of healthy Swedish bone marrow donors provided by the coordinating centre of the Bone Marrow Donors Worldwide Registries, Leiden, the Netherlands were used as controls. When this cohort of epithelial ovarian cancer patients was compared with healthy Swedish donors, the frequency of HLA-A1 and HLA-A2 gene/phenotype appears, although not statistically significant, to be increased in patients with ovarian carcinoma, while HLA-A3 was decreased. HLA-A2 homozygotes were twofold higher in patients. The A2-B8 haplotype was significantly increased (corrected P value). A2-B5, A2-B15, A2-DRB1*03, A2-DRB1*04, A2-B15-Cw3, and A2-B8-DRB1*03 had odds ratio as well as the level of the lower confidence interval above 1 and significant P value only when considered as single, non-corrected analysis. HLA-B15 and HLA-Cw3 were only present in HLA-A2-positive patients showing that the HLA-A2-HLA-Cw3 and HLA-B15 haplotypes were segregated. In this selected cohort with advanced disease, there are indications of an unusual overrepresentation of HLA class I and II genes/haplotypes as well as segregation for the HLA-A2-HLA-Cw3 and HLA-B15 haplotypes. These findings are presented as a descriptive analysis and need further investigations on a larger series of ovarian cancer patients to establish prognostic associations. PMID:17661908

  8. Estudo cefalométrico das alterações no perfil facial em pacientes Classe III dolicocefálicos submetidos à cirurgia ortognática bimaxilar Cephalometric study of the facial profile changes in Class III patients submitted to bimaxillary orthognathic surgery

    Directory of Open Access Journals (Sweden)

    Hewerson Santos Tavares

    2005-10-01

    Full Text Available O presente estudo avaliou as modificações no perfil facial de 15 pacientes portadores de má oclusão Classe III esquelética que foram submetidos a tratamento ortodôntico pré-cirúrgico e cirurgia ortognática bimaxilar estabilizada com fixação rígida. Oito pacientes foram submetidos à mentoplastia. Foram utilizadas telerradiografias pré-cirúrgicas (T1 e pós-cirúrgicas (T2 com um intervalo mínimo de 6 meses. Foram analisados deslocamentos horizontais e verticais em pontos do tecido ósseo e tecido mole. Foi realizada uma comparação entre os casos tratados com e sem mentoplastia (teste t mostrando não haver diferenças entre os grupos. A regressão linear múltipla evidenciou uma correlação significante no sentido horizontal para os pontos Pg e Pgm e vertical para os pontos Me e Mem. Foi encontrada baixa correlação para movimentos no sentido horizontal nos pontos Sena e A, e para os pontos Pn, Sn e Ph. No sentido vertical, os deslocamentos mais evidentes foram entre os pontos Pg, Gn e Me e Sena e A, porém com correlações de baixa intensidade.The present study evaluated the facial profile modifications in 15 skeletal Class III patients that were submitted to presurgical orthodontic treatment and orthognathic bimaxillary surgery stabilized with a rigid fixation. Eight of the patients have undergone to genioplastic surgery. Presurgical (T1 and late postsurgical (T2 radiographs taken apart with a minimum of 6 month interval had been used. The horizontal and vertical displacement of skeletal and soft tissue profile points were analyzed. The comparison of the cases submitted or not to a genioplastic surgery (t Test showed no differences for the displacement of the skeletal and soft tissue points. The multiple linear regression analysis showed a significant correlation for horizontal movements of the Pg and Pgm points and for vertical movements of the Me and Mem points. A low correlation was found for the horizontal movements of

  9. Treating dental crowding with mandibular incisor extraction in an Angle Class I patient.

    Science.gov (United States)

    Machado, Gislana Braga

    2015-01-01

    Mandibular dental crowding often encourages patients to seek orthodontic treatment. The orthodontist should decide between protrusion of incisors or decrease in dental volume so as to achieve proper alignment and leveling. The present study reports the treatment of an Angle Class I malocclusion adolescent female brachyfacial patient with severe mandibular dental crowding, increased curve of Spee and deep overbite. The patient was treated with extraction of a mandibular incisor. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO) as a requirement for the title of certified by the BBO. PMID:26154463

  10. Treating dental crowding with mandibular incisor extraction in an Angle Class I patient

    Directory of Open Access Journals (Sweden)

    Gislana Braga Machado

    2015-06-01

    Full Text Available Mandibular dental crowding often encourages patients to seek orthodontic treatment. The orthodontist should decide between protrusion of incisors or decrease in dental volume so as to achieve proper alignment and leveling. The present study reports the treatment of an Angle Class I malocclusion adolescent female brachyfacial patient with severe mandibular dental crowding, increased curve of Spee and deep overbite. The patient was treated with extraction of a mandibular incisor. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO as a requirement for the title of certified by the BBO.

  11. Angle Class II malocclusion treated with extraction of permanent teeth

    Directory of Open Access Journals (Sweden)

    Gustavo Mattos Barreto

    2013-08-01

    Full Text Available Angle Class II malocclusion associated with anterior open bite in adult patients demands a carefully elaborated orthodontic planning, aiming at restoring not only harmonious dental and facial esthetics, but also a balanced masticatory function. Orthognathic surgery or permanent teeth extraction are often the choice of treatment, therefore, treatment decision is related to all dental, skeletal and functional aspects. The present report discusses orthodontic compensation carried out by means of upper premolar extraction performed to correct the Class II canine relationship and, consequently, the anterior open bite, accepting that the upper incisors be retroclined. This clinical case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO as part of the requirements for obtaining the BBO Certification.

  12. Associação entre doença hepática gordurosa não alcoólica e marcadores de lesão/função hepática com componentes da síndrome metabólica em indivíduos obesos classe III Association between non-alcoholic fatty liver disease and liver function/injury markers with metabolic syndrome components in class III obese individuals

    Directory of Open Access Journals (Sweden)

    Gabriela Villaça Chaves

    2012-06-01

    Full Text Available OBJETIVO: Investigar a associação entre doença hepática gordurosa não alcoólica (DHGNA e os marcadores de lesão e função hepática com os componentes da síndrome metabólica (SM em indivíduos obesos classe III. MÉTODOS: A população estudada foi constituída por 144 pacientes com obesidade classe III (IMC > a 40 kg/m². A SM foi identificada segundo o critério do NCEP ATP III, por meio da determinação do perfil lipídico, glicemia e insulina basal. Foram quantificados ainda os marcadores de função e lesão hepática. A resistência à insulina (RI foi verificada pelo índice HOMA-IR e o diagnóstico da DHGNA por ressonância magnética. Os cálculos estatísticos foram realizados pelo programa estatístico SPSS na versão 13.0. A associação foi verificada pelo teste Mann-Whitney e qui-quadrado, com nível de significância de 5%. RESULTADOS: Foi encontrada associação significativa entre o diagnóstico de SM e DHGNA (χ² = 6,84; p = 0,01. Quanto aos componentes diagnósticos para SM, constatou-se associação positiva e significativa entre HDL-c (p = 0,05, circunferência da cintura (p OBJECTIVE: To investigate the association between non-alcoholic fatty liver disease (NAFLD and liver function/injury markers with components of metabolic syndrome (MS in class III obese individuals. METHODS: The study population consisted of 144 patients with class III obesity (body mass index [BMI] > 40 kg/m². MS was diagnosed according to the National Cholesterol Education Program - Adult Treatment Panel III (NCEP ATP III criteria, by determining the lipid profile, blood glucose and basal insulin. Liver function/injury markers were also quantified. Insulin resistance (IR was measured by HOMA-IR and NAFLD diagnosis was established by magnetic resonance imaging (MRI. Statistical calculations were performed by SPSS version 13.0. The association was assessed by the Mann-Whitney and Chi-square tests, with a level of significance set at 5

  13. Class II malocclusion occlusal severity description

    Directory of Open Access Journals (Sweden)

    Guilherme Janson

    2010-08-01

    Full Text Available OBJECTIVES: It is well known that the efficacy and the efficiency of a Class II malocclusion treatment are aspects closely related to the severity of the dental anteroposterior discrepancy. Even though, sample selection based on cephalometric variables without considering the severity of the occlusal anteroposterior discrepancy is still common in current papers. In some of them, when occlusal parameters are chosen, the severity is often neglected. The purpose of this study is to verify the importance given to the classification of Class II malocclusion, based on the criteria used for sample selection in a great number of papers published in the orthodontic journal with the highest impact factor. MATERIAL AND METHODS: A search was performed in PubMed database for full-text research papers referencing Class II malocclusion in the history of the American Journal of Orthodontics and Dentofacial Orthopedics (AJO-DO. RESULTS: A total of 359 papers were retrieved, among which only 72 (20.06% papers described the occlusal severity of the Class II malocclusion sample. In the other 287 (79.94% papers that did not specify the anteroposterior discrepancy severity, description was considered to be crucial in 159 (55.40% of them. CONCLUSIONS: Omission in describing the occlusal severity demands a cautious interpretation of 44.29% of the papers retrieved in this study.

  14. Relação entre o estado nutricional de vitamina a e a regressão da esteatose hepática após gastroplastia em Y- de- Roux para tratamento da obesidade classe III Relationship of the nutritional status of vitamin a and the regression of hepatic steatosis after Roux-en-Y gastric bypass surgery for treatment of class III obesity

    Directory of Open Access Journals (Sweden)

    Luiz Gustavo de Oliveira e Silva

    2012-12-01

    Full Text Available RACIONAL: A vitamina A participa de várias funções primordiais no organismo humano e as suas concentrações séricas podem estar diminuídas nas doenças crônicas não transmissíveis. OBJETIVO: Avaliar a relação entre o estado nutricional da vitamina A, e a regressão da esteatose hepática em indivíduos submetidos à gastroplastia em Y-de-Roux para tratamento da obesidade classe III. MÉTODOS: Foram estudados 30 pacientes obesos classe III, de ambos os sexos, com esteatose hepática, submetidos à gastroplastia em Y-de-Roux. Seis meses após a operação, os pacientes foram submetidos à ultrassonografia abdominal e distribuídos em dois grupos: grupo 1 - pacientes com esteatose detectada na ultrassonografia e grupo 2 - pacientes sem esteatose detectada na ultrassonografia. No pré-operatório e seis meses após a operação foram realizadas análises antropométricas e exames bioquímicos: insulina basal, glicemia, Homeostasis Model Assessment Index (HOMA IR, colesterol, HDL, LDL, triglicerídeos, AST, ALT, Gama-GT, albumina, bilirrubina total, retinol, e beta caroteno. RESULTADOS: A média de perda de peso foi de 35,05 + 10,47 (pBACKGROUND: Vitamin A participates in several essentials functions in the human body and their serum concentrations may be decreased in non-transmissible diseases. AIM: To assess the relationship of the nutritional status of Vitamin A through the serum concentrations of retinol and beta carotene, with regression of hepatic steatosis in individuals who undergone Roux-en-Y gastric bypass surgery for treatment of class III obesity. METHODS: Were included 30 individuals, male and female, submitted to Roux-en-Y gastric bypass for treatment of class III obesity, who were diagnosed through an abdominal ultrasonography as presenting hepatic steatosis. From the result of an ultrasonography screened six months after the surgical procedure those subjects were divided into two groups: group 1 - patients with steatosis

  15. Quantification of 4-methylimidazole in class III and IV caramel colors: validation of a new method based on heart-cutting two-dimensional liquid chromatography (LC-LC).

    Science.gov (United States)

    Moretton, Cédric; Crétier, Gérard; Nigay, Henri; Rocca, Jean-Louis

    2011-04-27

    4-Methylimidazole (4MeI) is a nitrogen compound formed during the manufacture of class III and IV caramel colors. The European Commission has limited its content to 250 ppm. Two methods were compared to perform 4MeI quantification in caramels. The first one, currently used and considered to be the reference method, consists of a hot extraction of caramel color with dichloromethane and an analysis of the acetyl derivative of the extract by gas chromatography coupled to mass spectrometry (GC-MS). The second method is based on the heart-cutting two-dimensional liquid chromatography technique (LC-LC) to directly separate 4MeI from the other components present in caramel color sample (diluted in water) in caramels. PMID:21381772

  16. Sinus lifting before Le Fort I maxillary osteotomy: a suitable method for oral rehabilitation of edentulous patients with skelettal class-III conditions: review of the literature and report of a case

    Directory of Open Access Journals (Sweden)

    Meyer Ulrich

    2007-01-01

    Full Text Available Abstract Background Functional rehabilitation of patients afflicted with severe mandibular and maxillary alveolar atrophy might be challenging especially in malformed patients. Methods Treatment planning using sinus lifting and implant placement before Le Fort I maxillary osteotomy in a patient with severe mandibular and posterior maxillary alveolar atrophy and skelettal class-III conditions due to cleft palate are described. Results A full functional and esthetic rehabilitation of the patient was achieved by a stepwise surgical approach performed through sinus lifting as the primary approach followed by implant placement and subsequent Le Fort I maxillary osteotomy to correct the maxillo-mandibular relation. Conclusion Stabilisation of the maxillary complex by a sinus lifting procedure in combination with computer aided implant placement as preorthodontic planning procedure before Le Fort I maxillary osteotomy seems to be suitable in order to allow ideal oral rehabilitation especially in malformed patients.

  17. Application of advanced reservoir characterization, simulation, and production optimization strategies to maximize recovery in slope and basin clastic reservoirs, West Texas (Delaware Basin), Class III

    Energy Technology Data Exchange (ETDEWEB)

    Dutton, Shirley P.; Flanders, William A.; Zirczy, Helena H.

    2000-05-24

    The objective of this Class 3 project was to demonstrate that detailed reservoir characterization of slope and basin clastic reservoirs in sandstones of the Delaware Mountain Group in the Delaware Basin of West Texas and New Mexico is a cost effective way to recover a higher percentage of the original oil in place through strategic placement of infill wells and geologically based field development. Phase 1 of the project, reservoir characterization, was completed this year, and Phase 2 began. The project is focused on East Ford field, a representative Delaware Mountain Group field that produces from the upper Bell Canyon Formation (Ramsey sandstone). The field, discovered in 1960, is operated by Oral Petco, Inc., as the East Ford unit. A CO{sub 2} flood is being conducted in the unit, and this flood is the Phase 2 demonstration for the project.

  18. A Determination of H_0 with the CLASS Gravitational Lens B1608+656 III. A Significant Improvement in the Precision of the Time Delay Measurements

    CERN Document Server

    Fassnacht, C D; Koopmans, L V E; Rusin, D

    2002-01-01

    The gravitational lens CLASS B1608+656 is the only four-image lens system for which all three independent time delays have been measured. This makes the system an excellent candidate for a high-quality determination of H_0 at cosmological distances. However, the original measurements of the time delays had large (12-20%) uncertainties, due to the low level of variability of the background source during the monitoring campaign. In this paper, we present results from two additional VLA monitoring campaigns. In contrast to the ~5% variations seen during the first season of monitoring, the source flux density changed by 25-30% in each of the subsequent two seasons. We analyzed the combined data set from all three seasons of monitoring to improve significantly the precision of the time delay measurements; the delays are consistent with those found in the original measurements, but the uncertainties have decreased by factors of two to three. We combined the delays with revised isothermal mass models to derive a mea...

  19. ULOF and unprotected blockage accident analyses of the 400MWth-class EFIT accelerator driven transmuter with the SIMMER-III code

    International Nuclear Information System (INIS)

    In the EUROTRANS Programme of the 6th FP of the EC the EFIT, the European Facility for Industrial Transmutation, a generic conceptual design of a full 400 MWth ADS transmuter loaded with a CERCER U-free fuel with an MgO matrix, is developed. The safety objectives for the EFIT are achieved on the basis of the defense-in-depth concept. For the safety assessment various protected and unprotected design basis conditions (DBC) and design extension conditions (DEC) transients have been analyzed as e.g. the protected and unprotected loss of flow (PLOF/ULOF), beam trip transients, over power transients and especially the unprotected blockage accidents (UBAs). Key safety analyses of the EFIT core have been performed with the SIMMER-III code, currently the only code which can handle core disruptive conditions for heavy liquid metal reactors. Unprotected transients set upper safety limits and play an important role in the overall safety assessment and transient behaviors of MgO based fuel and T91 cladding. Especially the high temperature range is still connected with significant uncertainties, therefore, unprotected accidents with a potential of fuel failure and gas release deserve special attention. In this paper, analyses of the ULOF and the UBA will be presented. Simulations of the core under the steady operation state have been carried out first, whose results show good agreement with the design data. In addition the safety parameters as e.g. the void worth of the core and the Doppler constant have been determined. In the ULOF analysis, the pump head is assumed to be completely lost within 1 or 5 seconds. Due to the loss of the pump head, coolant mass flow rate in the reactor will decrease and finally arrive at its new steady state because of the remained natural convection. Calculated results indicate that, under the current assumptions, the EFIT design can survive a ULOF without fuel pin failure whilst a larger safety margin exists if the pump halving time is longer

  20. Investigation of Class I, II and III Integrons among Acinetobacter Strains Isolated from Ventilator-Associated Pneumonia Patients in Intensive Care Unit of Rasoul Akram Hospital in Tehran, Iran

    Directory of Open Access Journals (Sweden)

    Hajar Mohammadi-Barzelighi

    2015-10-01

    Full Text Available Background: Multi-drug resistant strains of Acinetobacter spp. have created therapeutic problems worldwide. The objective of this study was to detect integrons  in Acinetobacter  spp. isolates  from Ventilator-Associated  Pneu- monia patients using PCR method.Methods: A total 51 Bronchoalveolar lavage samples were obtained from pa-tients in ICU and examined for Acinetobacter spp. infection by biochemical and PCR methods using blaOXA51-like primers. Antimicrobial susceptibility testing was performed using disk diffusion and MIC methods.Results: Among 51 patients with VAP (62.7% males, 35.2% females, mean age 53 year, 50 (98% were positive, with a high prevalence of gram-nega- tive bacteria, mainly Acinetobacter spp. (70%, from which A. baumani was detected in 34 (68% and A. lwoffii in 1 (2% of isolates. More than 90% of isolates were resistant to imipenem,  piperacillin+tazobactam,  third genera- tion cephalosporins and gentamicin, while the most effective antibiotic was colistin (100%. The correlation coefficient between disk diffusion and MIC was 0.808 (p = 0.001. Three Acinetobacter isolates (8% harbored integrase I gene but none of isolates contained Class II or III integrons.Conclusion: The results showed that colistin was an effective antibiotic andcan be used for treatment  of patients in ICU. Due to the high number of MDR isolates lacking Integrons it can be concluded that although class I in- tegrons are important among clinical isolates of A. baumannii, they have no significant  role  in  dissemination  of  antibiotic  resistance  genes  in  Rasoul Akram  Hospital in Tehran, Iran. The presence of IntI in A. lwoffii may be related to transfer of integron to A. baumannii which can be considered as an important threat for hospitalized patients.

  1. Root growth restraint can be an acclimatory response to low pH and is associated with reduced cell mortality: a possible role of class III peroxidases and NADPH oxidases.

    Science.gov (United States)

    Graças, J P; Ruiz-Romero, R; Figueiredo, L D; Mattiello, L; Peres, L E P; Vitorello, V A

    2016-07-01

    Low pH (Solanum lycopersicum cv Micro-Tom) roots were exposed directly or gradually to low pH through step-wise changes in pH over periods ranging from 4 to 24 h. Roots exposed gradually to pH 4.5 grew even less than those exposed directly, indicating a plant-coordinated response. Direct exposure to pH 4.0 suppressed root growth and caused high cell mortality, in contrast to roots exposed gradually, in which growth remained inhibited but cell viability was maintained. Total class III peroxidase activity increased significantly in all low pH treatments, but was not correlated with the observed differential responses. Use of the enzyme inhibitors salicylhydroxamic acid (SHAM) or diphenyleneiodonium chloride (DPI) suggest that peroxidase and, to a lesser extent, NADPH oxidase were required to prevent or reduce injury in all low pH treatments. However, a role for other enzymes, such as the alternative oxidase is also possible. The results with SHAM, but not DPI, were confirmed in tobacco BY-2 cells. Our results indicate that root growth inhibition from low pH can be part of an active plant response, and suggest that peroxidases may have a critical early role in reducing loss of cell viability and in the observed root growth constraint. PMID:26891589

  2. Caring for class III obese patients.

    Science.gov (United States)

    Gardner, Lea Anne

    2013-11-01

    The Pennsylvania Patient Safety Reporting System is a confidential, statewide Internet reporting system to which all Pennsylvania hospitals, outpatient-surgery facilities, and birthing centers, as well as some abortion facilities, must file information on medical errors.Safety Monitor is a column from Pennsylvania's Patient Safety Authority, the authority that informs nurses on issues that can affect patient safety and presents strategies they can easily integrate into practice. For more information on the authority, visit www.patientsafetyauthority.org. For the original article discussed in this column or for other articles on patient safety, click on "Patient Safety Advisories" and then "Advisory Library" in the left-hand navigation menu. PMID:24149276

  3. Mathematics III

    OpenAIRE

    Viader Canals, Pelegrí

    2013-01-01

    Apunts de l'assignatura Mathematics III del Grau en International Business Economics del curs 2012-2013. Conté : Diagonalization, Difference Equations, Differential Equations, Lagrange-Kuhn-Tucker, Second order Difference Equations.

  4. Basel III

    OpenAIRE

    Štrbová, Barbora

    2014-01-01

    The aim of this thesis is to analyze current capital adequacy in Europe under regulatory framework Basel III and compare the state of its implementation within European banks and Slovak financial sector, which is represented by two Slovak case banks. Firstly it is focused on the two previous regulatory frameworks, especially on their capital adequacy and three-pillar structure of Basel II. Then we proceed to present the new regulatory framework Basel III. The third regulatory framework of the...

  5. Posição habitual de língua e padrão de deglutição em indivíduo com oclusão classe III, pré e pós-cirurgia ortognática Tongue's rest position and deglutition standards in a patient with malocclusion Class III, pre and post orthognathic surgery

    Directory of Open Access Journals (Sweden)

    Cássia Sígolo

    2009-06-01

    Full Text Available TEMA: os distúrbios miofuncionais orofaciais dos indivíduos que apresentam desproporções maxilomandibulares podem estar relacionados à condição muscular orofacial e às diferentes funções por elas realizadas. PROCEDIMENTOS: a paciente realizou um exame radiográfico de videofluoroscopia no qual se observou quantas deglutições foram necessárias para total limpeza das valéculas e qual foi a posição da língua após a deglutição de saliva. O exame foi realizado com bário líquido e pão de queijo. RESULTADOS: na avaliação pré-operatória, foi encontrada a língua posicionada no soalho da cavidade oral; mastigação com movimento compensatório de língua, com amassamento do alimento pela língua, contra o palato; deglutição com projeção anterior de língua, diminuição da elevação de dorso de língua; elevação de palato mole e laringe adequada; diminuição de ejeção oral para líquido e função de clearance faríngeo completa para líquidos e sólidos. No exame pós-operatório, foi observada a posição habitual de língua em soalho da boca; mastigação com movimento compensatório de língua, com amassamento do alimento pela língua, contra o palato; elevação de palato mole e laringe adequada, ejeção oral satisfatória para líquido e função de clearance faríngeo completo para líquidos e sólidos. CONCLUSÃO: foi observado padrão adaptativo funcional em mastigação e deglutição mantido, mesmo após a cirurgia corretiva para a adequação da deformidade dentofacial, apesar da melhora da força de ejeção oral.BACKGROUND: the orofacial myofunctional disorders of individuals that have maxillomandibular disproportions can be related the orofacial muscular condition and the different functions accomplished by them. PROCEDURES: the patient was submitted to a radiographic video-fluoroscopic examination where in which we observed how many swallowing were needed to complete full cleaning of the valecular

  6. Fermilab III

    International Nuclear Information System (INIS)

    The total ongoing plans for Fermilab are wrapped up in the Fermilab III scheme, centrepiece of which is the proposal for a new Main Injector. The Laboratory has been awarded a $200,000 Illinois grant which will be used to initiate environmental assessment and engineering design of the Main Injector, while a state review panel recommended that the project should also benefit from $2 million of funding

  7. Precipitates of Al(III), Sc(III), and La(III) at the muscovite-water interface.

    Science.gov (United States)

    Saslow Gomez, Sarah A; Geiger, Franz M

    2014-11-20

    The interaction of Al(III), Sc(III), and La(III) with muscovite-water interfaces was studied at pH 4 and 10 mM NaCl using second harmonic generation (SHG) and X-ray photoelectron spectroscopy (XPS). SHG data for Sc(III) and La(III) suggest complete and/or partial irreversible adsorption that is attributed by XPS to the growth of Sc(III) and La(III) hydroxides/oxides on the muscovite surface. Al(III) adsorption appears to coincide with the growth of gibbsite (Al(OH)3) deposits on the muscovite surface, as indicated by the magnitude of the interfacial potential computed from the SHG data. This interpretation of the data is consistent with previous studies reporting the epitaxial growth of gibbsite on the muscovite surface under similar conditions. The implication of our findings is that the surface charge density of mica may change (and in the case of Al(III), even flip sign from negative (mica) to positive (gibbsite)) when Al(III), Sc(III), or La(III) is present in aqueous phases in contact with heterogeneous geochemical media rich in mica-class minerals, even at subsaturation conditions. PMID:25380548

  8. Class size versus class composition

    DEFF Research Database (Denmark)

    Jones, Sam

    Raising schooling quality in low-income countries is a pressing challenge. Substantial research has considered the impact of cutting class sizes on skills acquisition. Considerably less attention has been given to the extent to which peer effects, which refer to class composition, also may affect...

  9. Word classes

    DEFF Research Database (Denmark)

    Rijkhoff, Jan

    2007-01-01

    This article provides an overview of recent literature and research on word classes, focusing in particular on typological approaches to word classification. The cross-linguistic classification of word class systems (or parts-of-speech systems) presented in this article is based on statements found...... in grammatical descriptions of some 50 languages, which together constitute a representative sample of the world’s languages (Hengeveld et al. 2004: 529). It appears that there are both quantitative and qualitative differences between word class systems of individual languages. Whereas some languages...... employ a parts-of-speech system that includes the categories Verb, Noun, Adjective and Adverb, other languages may use only a subset of these four lexical categories. Furthermore, quite a few languages have a major word class whose members cannot be classified in terms of the categories Verb – Noun...

  10. Effects of long-term treatment with testosterone on weight and waist size in 411 hypogonadal men with obesity classes I-III: observational data from two registry studies

    OpenAIRE

    Saad, F.; Yassin, A; Doros, G; Haider, A

    2015-01-01

    Background/Objectives: Long-term testosterone replacement therapy (TRT) up to 5 years has been shown to produce progressive and sustainable weight loss (WL) in hypogonadal men. This study investigated effects of long-term TRT up to 8 years in hypogonadal men with different obesity classes. Subjects/Methods: From two independent observational registries we identified a total of 411 obese, hypogonadal men receiving TRT in urological clinics. The effects of TRT on anthropometric as well as metab...

  11. 49 CFR 173.468 - Test for LSA-III material.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Test for LSA-III material. 173.468 Section 173.468... SHIPMENTS AND PACKAGINGS Class 7 (Radioactive) Materials § 173.468 Test for LSA-III material. (a) LSA-III Class 7 (radioactive) material must meet the test requirement of paragraph (b) of this section....

  12. Avaliação das queixas estético-funcionais em pacientes portadores de deformidades dentofaciais Assessment of aesthetic and functional complaints in patients with dentofacial deformities

    Directory of Open Access Journals (Sweden)

    Dario Ravazzi Ambrizzi

    2007-10-01

    Full Text Available OBJETIVO: avaliar as queixas relatadas por pacientes portadores de deformidades dentofaciais como fatores motivadores na procura do tratamento ortodôntico-cirúrgico. METODOLOGIA: foram verificados 130 prontuários de pacientes em tratamento no CEDEFACE - Araraquara, apresentando um período pós-operatório mínimo de 6 meses e idade média de 30,9 anos. A classificação dos tipos de deformidades foi realizada por meio de análise das telerradiografias e das fotografias, sendo subdivididas em três grupos, de acordo com suas características de perfil facial. As informações referentes às queixas foram colhidas por meio de questionários e divididas em duas categorias: queixa principal e queixas secundárias. Em relação à análise estatística, utilizaram-se medidas de tendência central (média e mediana e de variabilidade (variação e desvio-padrão para descrever as variáveis numéricas de idade. As variáveis categóricas de gênero, deformidades dentofaciais e queixas foram descritas através da distribuição de freqüências, com nível de significância de 5%. RESULTADOS: observou-se predominância do gênero feminino, na razão de 2:1. Na maioria das vezes, a deformidade requeria tratamento somente na maxila ou somente na mandíbula. No gênero feminino predominaram as deformidades de perfil convexo (46%; no gênero masculino houve predominância de deformidades de perfil côncavo (48,8%. As queixas principais evidenciaram que o anseio estético é predominante, tanto no gênero feminino quanto no masculino. CONCLUSÃO: os anseios de melhora estética foram predominantes em ambos os gêneros. A maioria dos pacientes também apresentou anseio por melhora funcional. Queixas de dor orofacial foram observadas em metade da casuística, sendo a segunda queixa mais relatada.AIM: To assess the complaints referred by patients with dentofacial deformities as motivation for seeking orthodontic-surgical treatment. METHODS: Were examinated

  13. Tratamento da má oclusão de Classe II, divisão 1 de Angle, com protrusão maxilar utilizando-se recursos ortopédicos Class II, division 1, with maxillar protrusion's treatment employing orthopedic approachs

    Directory of Open Access Journals (Sweden)

    Carla Maria Melleiro Gimenez

    2007-12-01

    Full Text Available OBJETIVO: o presente trabalho tem o propósito de apresentar uma revisão da literatura acerca do tratamento da má oclusão de Classe II, divisão 1 de Angle, tendo a protrusão maxilar como o principal componente dessa má oclusão, durante a fase de crescimento e desenvolvimento craniofacial. Serão apresentadas as características de cada um desses aparelhos, os seus componentes, a forma adequada de utilização, os seus mecanismos de ação e, principalmente, os seus efeitos em todo o complexo dentofacial. CONCLUSÃO: nos casos em que se verifica apenas a protrusão maxilar, sem envolvimento mandibular, e se faz necessário o controle vertical, pode ser indicado o AEB, conjugado ao aparelho removível derivado do aparelho preconizado por Thurow. Já nas situações de combinação da protrusão maxilar com a retrusão mandibular, uma opção de tratamento é o ativador combinado à ancoragem extrabucal.AIM: The purpose of this research is to review the literature about the treatment of Class II, division 1 malocclusion with maxillary protrusion, during the growth and development period. This review addresses the characteristics of these appliances, their components, correct use, action mechanisms, and mainly their consequences in dentofacial complex. CONCLUSIONS: In patients with maxillary protrusion and with no mandibular component, it may be indicated the use of a maxillary splint similar to the one suggested by Thurow. However, in patients with maxillary protrusion and mandibular retrusion, it may be indicated an activator associated with extra oral anchorage.

  14. Moran sets and Moran classes

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The purpose of this survey is to present Moran sets and Moran classes which generalize the classical selfsimilar sets from the following points: ( i ) The placements of the basic sets at each step of the constructions can be arbitrary; (ii) the contraction ratios may be different at each step; and (iii) the lower limit of the contraction ratios permits zero. In this discussion we will present geometrical properties and results of dimensions of these sets and classes,and discuss conformal Moran sets and random Moran sets as well.``

  15. Class distinction

    Science.gov (United States)

    White, M. Catherine

    Typical 101 courses discourage many students from pursuing higher level science and math courses. Introductory classes in science and math serve largely as a filter, screening out all but the most promising students, and leaving the majority of college graduates—including most prospective teachers—with little understanding of how science works, according to a study conducted for the National Science Foundation. Because few teachers, particularly at the elementary level, experience any collegiate science teaching that stresses skills of inquiry and investigation, they simply never learn to use those methods in their teaching, the report states.

  16. Angle Class I malocclusion treated with lower incisor extraction

    Directory of Open Access Journals (Sweden)

    Vanessa Leal Tavares Barbosa

    2013-06-01

    Full Text Available In planning orthodontic cases that include extractions as an alternative to solve the problem of negative space discrepancy, the critical decision is to determine which teeth will be extracted. Several aspects must be considered, such as periodontal health, orthodontic mechanics, functional and esthetic alterations, and treatment stability. Despite controversies, extraction of teeth to solve dental crowding is a therapy that has been used for decades. Premolar extractions are the most common, but there are situations in which atypical extractions facilitate mechanics, preserve periodontal health and favor maintenance of the facial profile, which tends to unfavorably change due to facial changes with age. The extraction of a lower incisor, in selected cases, is an effective approach, and literature describes greater post-treatment stability when compared with premolar extractions. This article reports the clinical case of a patient with Angle Class I malocclusion and upper and lower anterior crowding, a balanced face and harmonious facial profile. The presence of gingival and bone recession limited large orthodontic movements. The molars and premolars were well occluded, and the discrepancy was mainly concentrated in the anterior region of the lower dental arch. The extraction of a lower incisor in the most ectopic position and with compromised periodontium, associated with interproximal stripping in the upper and lower arches, was the alternative of choice for this treatment, which restored function, providing improved periodontal health, maintained facial esthetics and allowed finishing with a stable and balanced occlusion. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO, as part of the requirements for obtaining the BBO Diplomate title.

  17. Sub-classes and evolution stability of Wolfram's classesin the total-rule cellular automata

    Institute of Scientific and Technical Information of China (English)

    YAN Guangwu; TIAN Feng; DONG Yinfeng

    2004-01-01

    In this paper, we propose a concept of sub-classes and its evolution stability for the Wolfram's classes. Firstly, we obtain the sub-classes of the Wolfram's class IV, gene-piece of these sub-classes and their existing circumstance. Secondly, we introduce a new concept, the evolution stability, for the Wolfram's classes and sub-classes of Wolfram's class IV. Lastly, we find that Wolfram's classes I, II, and III have the evolution stability, but sub-classes of the Wolfram's class IV have not the evolution stability for the total rule cellular automata.

  18. Gold(III) Compounds as New Family of Anticancer Drugs

    OpenAIRE

    Luigi Messori; Giordana Marcon; Pierluigi Orioli

    2003-01-01

    Gold(III) complexes are emerging as a new class of metal complexes with outstanding cytotoxic properties and are presently being evaluated as potential antitumor agents. This renewed interest is the result of recent studies in which various gold(III) complexes have been shown to be stable under physiological conditions and to manifest relevant antiproliferative properties against selected human tumor cell lines. The pharmacological investigation of some representative gold(III) complexes has ...

  19. Tratamento conservador de uma má oclusão Classe I de Angle, com atresia maxilar e apinhamento anterior The conservative treatment of Class I malocclusion with maxillary transverse deficiency and anterior teeth crowding

    Directory of Open Access Journals (Sweden)

    Lincoln I. Nojima

    2011-10-01

    Full Text Available Este artigo relata o tratamento de uma paciente do sexo feminino, com 15 anos de idade, má oclusão Classe I de Angle, severo apinhamento anterossuperior, desvio da linha média superior para o lado esquerdo e atresia maxilar, associada à mordida cruzada posterior. Os procedimentos executados envolveram a expansão maxilar com disjuntor palatino do tipo Haas modificado e montagem de aparelho fixo com sistema Edgewise standard. Foram realizados desgastes proximais nos incisivos e caninos inferiores para o alinhamento anterior, bem como redução da discrepância de Bolton com excesso inferior. Esse caso foi apresentado à diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO, representando a categoria livre escolha, como parte dos requisitos para a obtenção do título de Diplomado pelo BBO.This article reports the treatment of a 15-years-old female patient, with Class I malocclusion, severe upper anterior crowding, midline deviation to the left side and maxillary transverse deficiency associated with posterior crossbite. The procedures involved rapid maxillary expansion with modified Haas appliance and the use of Edgewise standard system. Proximal wear were performed to the alignment of mandibular incisors, as well as to reduce the Bolton discrepancy. This case was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO, representative of category free, as partial fulfillment of the requirements for obtaining the title of BBO Diplomate.

  20. Two new class III G6PD variants [G6PD Tunis (c.920A>C: p.307Gln>Pro) and G6PD Nefza (c.968T>C: p.323 Leu>Pro)] and overview of the spectrum of mutations in Tunisia.

    Science.gov (United States)

    Benmansour, Ikbel; Moradkhani, Kamran; Moumni, Imen; Wajcman, Henri; Hafsia, Raouf; Ghanem, Abderraouf; Abbès, Salem; Préhu, Claude

    2013-02-01

    We screened 423 patients referred to our laboratory after hemolysis triggered by fava beans ingestion, neonatal jaundice or drug hemolysis. Others were asymptomatic but belonged to a family with a history of G6PD deficiency. The determination of enzymatic activity using spectrophotometric method, revealed 293 deficient (143 males and 150 females). The molecular analysis was performed by a combination of PCR-RFLP and DNA sequencing to characterize the mutations causing G6PD deficiency. 14 different genotypes have been identified : G6PD A(-) (376A>G;202G>A) (46.07%) and G6PD Med (33.10%) were the most common variants followed by G6PD Santamaria (5.80%), G6PD Kaiping (3.75%), the association [c.1311T and IVS11 93c] (3.75%), G6PD Chatham (2.04%), G6PD Aures (1.70%), G6PD A(-) Betica (0.68%), the association [ 376G;c.1311T;IVS11 93c] (0.68%), G6PD Malaga, G6PD Canton and G6PD Abeno respectively (0.34%). Two novel missense mutations were identified (c.920A>C: p.307Gln>Pro and c.968T>C: p.323 Leu>Pro). We designated these two class III variants as G6PD Tunis and G6PD Nefza. A mechanism which could account for the defective activity is discussed. PMID:22963789

  1. Class IIa Bacteriocins: Current Knowledge and Perspectives

    Science.gov (United States)

    Belguesmia, Yanath; Naghmouchi, Karim; Chihib, Nour-Eddine; Drider, Djamel

    Lactic acid bacteria (LAB) are known to produce antibacterial peptides and small proteins called bacteriocins, which enable them to compete against other bacteria in the environment. Bacteriocins fall structurally and chemically into three different classes, I, II, and III. Bacteriocins are ribosomally synthesized peptides with antagonism against closely related bacteria. This late observation has evolved because bacteriocins active against Gram-negative bacteria have recently been reported. Members of class IIa bacteriocins, referred to as pediocin-like bacteriocins, are among the most studied bacteriocins. This chapter is aimed at providing an updated review on the biology of class IIa bacteriocins.

  2. Compendium of Lecture Notes for Training Class III Meteorological Personnel.

    Science.gov (United States)

    Retallack, B. J.

    This compendium of lecture notes provides a course of study for persons who may be involved in a variety of specialized meteorological tasks. The course is considered to be advanced and assumes students have had introductory experiences in meteorology and earth science (covered in a similar compendium). The material is presented in seven units…

  3. Teacher's Questions in Reading Classes

    OpenAIRE

    Zuliati Rohmah

    2002-01-01

    Abstract: The present paper discusses an English teacher's questions in Reading classes at MAN Malang III. Types of questions, functions of teacher's questions, question levels and the strategies applied by the teacher were put as the research problems. Non-participant observa­tion was applied to collect the data with the researcher as the main in­strument aided by field-notes and a tape recorder. It was found that the distribution of the questions did not allow the students to talk longer ...

  4. PENGGUNAAN INCLINED BITE PLANE SEBAGAI ALAT BANTU UNTUK KOREKSI GIGITAN SILANG ANTERIOR PADA KASUS MALOKLUSI KLAS III SKELETAL

    OpenAIRE

    Amutavia P. Artsianti P.; Erwin Siregar

    2015-01-01

    Anterior crossbite occurs in children and adult. This anterior crossbite could be a dental (pseudo class III) or a skeletal class III malocclusions. A 15 year old young female came to orthodontic clinic RSGM FKGUI with maxillary dental crowding which canines were more protruded. The dental of mandible were more protruded than maxillary dental. The clinical examination, anamnesis, functional analyses and cephalometric evaluation and model study showed that it was a skeletal class III malocclus...

  5. Class Vectors: Embedding representation of Document Classes

    OpenAIRE

    Sachan, Devendra Singh; Kumar, Shailesh

    2015-01-01

    Distributed representations of words and paragraphs as semantic embeddings in high dimensional data are used across a number of Natural Language Understanding tasks such as retrieval, translation, and classification. In this work, we propose "Class Vectors" - a framework for learning a vector per class in the same embedding space as the word and paragraph embeddings. Similarity between these class vectors and word vectors are used as features to classify a document to a class. In experiment o...

  6. Dentofacial and Cranial Changes in Down Syndrome

    OpenAIRE

    Shukla, Deepika; Bablani, Deepika; Chowdhry, Aman; Thapar, Raveena; Gupta, Puneet; Mishra, Shashwat

    2014-01-01

    Objectives This study aimed to determine the prevalence of certain oral characteristics usually associated with Down syndrome and to determine the oral health status of these patients. Methods The cross-sectional study was conducted among patients attending a special education program at Faculty of Dentistry, Jamia Millia Islamia, Delhi, India. The study design consisted of closed-ended questions on demographic characteristics (age, sex, and education and income of parents), dietary habits, a...

  7. Dentofacial characteristics in William′s syndrome

    OpenAIRE

    P Poornima; Piyusha S Patil; V V Subbareddy; Geetika Arora

    2012-01-01

    William′s syndrome is a chromosomal disorder characterized by multisystem, congenital and panethnic occurrence, characterized by a number of developmental and physical abnormalities. This case report describes the dental management of a 10-year-old male patient with William′s syndrome who had multiple dental problems such as caries, periodontal disease and malocclusion.

  8. Teachers in Class

    Science.gov (United States)

    Van Galen, Jane

    2008-01-01

    In this article, I argue for a closer read of the daily "class work" of teachers, as posited by Reay, 1998. In developing exploratory class portraits of four teachers who occupy distinctive social positions (two from working-class homes now teaching upper-middle-class children and two from upper-middle-class homes now teaching poor children), I…

  9. Does Class Size Matter?

    Science.gov (United States)

    Ehrenberg, Ronald G.; Brewer, Dominic J.; Gamoran, Adam; Willms, J. Douglas

    2001-01-01

    Reports on the significance of class size to student learning. Includes an overview of class size in various countries, the importance of teacher adaptability, and the Asian paradox of large classes allied to high test scores. (MM)

  10. Má oclusão Classe I de Angle, com mordida aberta anterior, tratada com extração de dentes permanentes Angle Class I malocclusion, with anterior open bite, treated with extraction of permanent teeth

    Directory of Open Access Journals (Sweden)

    Mírian Aiko Nakane Matsumoto

    2011-02-01

    Full Text Available A mordida aberta é uma anomalia com características distintas que, além da complexidade dos múltiplos fatores etiológicos, traz consequências estéticas e funcionais. Muitas alternativas têm sido utilizadas em seu tratamento, entre elas a grade palatina, forças ortopédicas, ajuste oclusal, camuflagem com ou sem exodontias, mini-implantes ou miniplacas e cirurgia ortognática. O diagnóstico preciso e a determinação da etiologia permitem estabelecer os objetivos e o plano de tratamento ideal para essa má oclusão. O presente relato descreve o tratamento de uma má oclusão Classe I de Angle, com padrão esquelético de Classe II e mordida aberta anterior, realizado em duas fases e que foi apresentado à diretoria do Board Brasileiro de Ortodontia e Ortopedia Facial (BBO, representando a categoria 2, como parte dos requisitos para a obtenção do título de Diplomado pelo BBO.Open bite is an anomaly with distinct characteristics which, in addition to involving complex, multiple etiologic factors, entails aesthetic and functional consequences. Many alternative approaches have been employed to treat open bite, including palatal crib, orthopedic forces, occlusal adjustment, camouflage with or without extractions, mini-implants or mini-plates, and orthognathic surgery. By determining accurate diagnosis and etiology professionals can set the goals and ideal treatment plan for this malocclusion. This report, describing the two stages treatment of a Angle Class I malocclusion with Class II skeletal pattern and anterior open bite, was presented to the Brazilian Board of Orthodontics and Dentofacial Orthopedics (BBO, representative of category 2, as partial fulfillment of the requirements for obtaining the title of BBO Diplomate.

  11. 41 CFR 301-10.162 - When may I use other than coach-class train accommodations?

    Science.gov (United States)

    2010-07-01

    ... Management Federal Travel Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ALLOWABLE TRAVEL EXPENSES... duration of the special accommodation; and (iii) A recommendation as to the suitable class...

  12. Basel III B: Basel III Overview

    OpenAIRE

    Christian M. McNamara; Michael Wedow; Andrew Metrick

    2014-01-01

    In the wake of the financial crisis of 2007-2009, the Basel Committee on Banking Supervision (BCBS) faced the critical task of diagnosing what went wrong and then updating regulatory standards aimed at preventing it from occurring again.  In seeking to strengthen the microprudential regulation associated with the earlier Basel Accords while also adding a macroprudential overlay, Basel III consists of proposals in three main areas intended to address 1) capital reform, 2) liquidity standards, ...

  13. Workshop 96. Part III

    International Nuclear Information System (INIS)

    Part III of the proceedings contain 155 contributions in various fields of science and technology including nuclear engineering, environmental science, and biomedical engineering. Out of these, 10 were selected to be inputted in INIS. (P.A.)

  14. Characterization of Caramel Colours I, II and III.

    Science.gov (United States)

    Licht, B H; Shaw, K; Smith, C; Mendoza, M; Orr, J; Myers, D V

    1992-05-01

    Groups of representative samples of Caramel Colours I, II, and III were characterized in order to assess the compositional uniformity within each class and to determine differences between each class. Compositional uniformity within each class was demonstrated by fractionation of the caramel samples and analysis by UV and visible absorbance, HPLC and chemical analysis. Although there was overlap between certain parameters of one or more caramel colour classes, the overall 'fingerprint' for each class, based on several different parameters, was distinctly unique. Such parameters included net ionic charge, absorbance properties, nitrogen and sulphur content, specific low molecular weight compounds and HPLC profiles. HPLC analysis revealed unique profiles within each class and distinct differences between classes. The data presented here for Caramel Colours I, II, and III, and elsewhere for Caramel Colour IV, indicate that each of the four classes can be considered as separate and that, throughout each class, the samples characterized constitute a homologous series of mixtures in terms of chemical composition. PMID:1644378

  15. Loosely coupled class families

    DEFF Research Database (Denmark)

    Ernst, Erik

    2001-01-01

    Families of mutually dependent classes that may be accessed polymor- phically provide an advanced tool for separation of concerns, in that it enables client code to use a group of instances of related classes safely without depending on the exact classes involved. However, class families which are...... expressed using virtual classes seem to be very tightly coupled internally. While clients have achieved the freedom to dynamically use one or the other family, it seems that any given family contains a xed set of classes and we will need to create an entire family of its own just in order to replace one of...... the members with another class. This paper shows how to express class families in such a manner that the classes in these families can be used in many dierent combinations, still enabling family polymorphism and ensuring type safety....

  16. Protein-water dynamics in antifreeze protein III activity

    Science.gov (United States)

    Xu, Yao; Bäumer, Alexander; Meister, Konrad; Bischak, Connor G.; DeVries, Arthur L.; Leitner, David M.; Havenith, Martina

    2016-03-01

    We combine Terahertz absorption spectroscopy (THz) and molecular dynamics (MD) simulations to investigate the underlying molecular mechanism for the antifreeze activity of one class of antifreeze protein, antifreeze protein type III (AFP-III) with a focus on the collective water hydrogen bond dynamics near the protein. After summarizing our previous work on AFPs, we present a new investigation of the effects of cosolutes on protein antifreeze activity by adding sodium citrate to the protein solution of AFP-III. Our results reveal that for AFP-III, unlike some other AFPs, the addition of the osmolyte sodium citrate does not affect the hydrogen bond dynamics at the protein surface significantly, as indicated by concentration dependent THz measurements. The present data, in combination with our previous THz measurements and molecular simulations, confirm that while long-range solvent perturbation is a necessary condition for the antifreeze activity of AFP-III, the local binding affinity determines the size of the hysteresis.

  17. Polymerase (Pol) III TATA Box-Binding Protein (TBP)-Associated Factor Brf Binds to a Surface on TBP Also Required for Activated Pol II Transcription

    OpenAIRE

    Shen, Yuhong; Kassavetis, George A.; Bryant, Gene O.; Berk, Arnold J.

    1998-01-01

    The TATA box-binding protein (TBP) plays an essential role in transcription by all three eukaryotic nuclear RNA polymerases, polymerases (Pol) I, II, and III. In each case, TBP interacts with class-specific TBP-associated factors (TAFs) to form class-specific transcription initiation factors. For yeast Pol III transcription, TBP associates with Brf (from TFIIB-related factor) and B", two Pol III TAFs, to form Pol III transcription factor TFIIIB. Here, we identify TBP surface residues that are...

  18. A Virtual Class Calculus

    DEFF Research Database (Denmark)

    Ernst, Erik; Ostermann, Klaus; Cook, William Randall

    2006-01-01

    , statically typed model for virtual classes has been a long-standing open question. This paper presents a virtual class calculus, vc, that captures the essence of virtual classes in these full-fledged programming languages. The key contributions of the paper are a formalization of the dynamic and static...

  19. Fusion Power Demonstration III

    International Nuclear Information System (INIS)

    This is the third in the series of reports covering the Fusion Power Demonstration (FPD) design study. This volume considers the FPD-III configuration that incorporates an octopole end plug. As compared with the quadrupole end-plugged designs of FPD-I and FPD-II, this octopole configuration reduces the number of end cell magnets and shortens the minimum ignition length of the central cell. The end-cell plasma length is also reduced, which in turn reduces the size and cost of the end cell magnets and shielding. As a contiuation in the series of documents covering the FPD, this report does not stand alone as a design description of FPD-III. Design details of FPD-III subsystems that do not differ significantly from those of the FPD-II configuration are not duplicated in this report

  20. Lutetium(III cyclotetraphosphate

    Directory of Open Access Journals (Sweden)

    Aïcha Mbarek

    2010-06-01

    Full Text Available Single crystals of the title compound, tetralutetium(III tris(cyclotetraphosphate, Lu4(P4O123, were obtained by solid-state reaction. The cubic structure is isotypic with its AlIII and ScIII analogues and is built up from four-membered (P4O124− phosphate ring anions (overline{4} symmetry, isolated from each other and further linked through isolated LuO6 octahedra (.3. symmetry via corner sharing. Each LuO6 octahedron is linked to six (P4O124− rings, while each (P4O124− ring is linked to eight LuO6 octahedra.

  1. III-V microelectronics

    CERN Document Server

    Nougier, JP

    1991-01-01

    As is well known, Silicon widely dominates the market of semiconductor devices and circuits, and in particular is well suited for Ultra Large Scale Integration processes. However, a number of III-V compound semiconductor devices and circuits have recently been built, and the contributions in this volume are devoted to those types of materials, which offer a number of interesting properties. Taking into account the great variety of problems encountered and of their mutual correlations when fabricating a circuit or even a device, most of the aspects of III-V microelectronics, from fundamental p

  2. Summary of Session III

    OpenAIRE

    Furman, M.A.

    2002-01-01

    This is a summary of the talks presented in Session III "Simulations of Electron-Cloud Build Up" of the Mini-Workshop on Electron-Cloud Simulations for Proton and Positron Beams ECLOUD-02, held at CERN, 15-18 April 2002.

  3. PENGGUNAAN FACE-MASK & EKSPANSI PALATAL PADA PERAWATAN MALOKLUSI KLAS III (Studi Pustaka)

    OpenAIRE

    Krisnawati Krisnawati

    2015-01-01

    Class III skeletal anomaly is one of the most difficult malocclusions to correct in orthodontics. Orthodontist usually involved chincup appliances to restrain mandibular growth, camouflage techniques to advances maxillary incisors and retract mandibular incisors or waiting untul growth ceased to pursue orthognathic surgery. Many studies found that most of Class III malocclusions were characterized by maxillary retrognathism. In the late 1960s, the Delaire mask was popularized to protract the ...

  4. Ultradiscrete limit of Bessel function type solutions of the Painlev\\'{e} III equation

    OpenAIRE

    Isojima, Shin

    2014-01-01

    An ultradiscrete analog of the Bessel function is constructed by taking the ultradiscrete limit for a $q$-difference analog of the Bessel function. Then, a direct relationship between a class of special solutions for the ultradiscrete Painlev\\'{e} III equation and those of the discrete Painlev\\'{e} III equation which have a determinantal structure is established.

  5. Semantic Analysis of Virtual Classes and Nested Classes

    DEFF Research Database (Denmark)

    Madsen, Ole Lehrmann

    1999-01-01

    Virtual classes and nested classes are distinguishing features of BETA. Nested classes originated from Simula, but until recently they have not been part of main stream object- oriented languages. C++ has a restricted form of nested classes and they were included in Java 1.1. Virtual classes is the...... classes and parameterized classes have been made. Although virtual classes and nested classes have been used in BETA for more than a decade, their implementation has not been published. The purpose of this paper is to contribute to the understanding of virtual classes and nested classes by presenting the...

  6. Class network routing

    Science.gov (United States)

    Bhanot, Gyan; Blumrich, Matthias A.; Chen, Dong; Coteus, Paul W.; Gara, Alan G.; Giampapa, Mark E.; Heidelberger, Philip; Steinmacher-Burow, Burkhard D.; Takken, Todd E.; Vranas, Pavlos M.

    2009-09-08

    Class network routing is implemented in a network such as a computer network comprising a plurality of parallel compute processors at nodes thereof. Class network routing allows a compute processor to broadcast a message to a range (one or more) of other compute processors in the computer network, such as processors in a column or a row. Normally this type of operation requires a separate message to be sent to each processor. With class network routing pursuant to the invention, a single message is sufficient, which generally reduces the total number of messages in the network as well as the latency to do a broadcast. Class network routing is also applied to dense matrix inversion algorithms on distributed memory parallel supercomputers with hardware class function (multicast) capability. This is achieved by exploiting the fact that the communication patterns of dense matrix inversion can be served by hardware class functions, which results in faster execution times.

  7. Fostering a Middle Class

    Institute of Scientific and Technical Information of China (English)

    YAO BIN

    2011-01-01

    Though there is no official definition of "middle class" in China,the tag has become one few Chinese people believe they deserve anyway.In early August,the Chinese Academy of Social Sciences released a report on China's urban development,saying China had a middle-class population of 230 million in 2009,or 37 percent of its urban residents.It also forecast half of city dwellers in China would be part of the middle class by 2023.

  8. New laser classes

    International Nuclear Information System (INIS)

    By an up-dated international standard (IEC 60825-1 + Amendment 2) on laser safety some new laser classes are introduced. The new set of laser classes consists of 1, 1M, 2, 2M, 3R, 3B, and 4. This is a result of intense discussions in the committee and was laid down in 2000, slightly adjusted 2001. The previous classes 1, 2, 3A, 3B, and 4, established since more than 25 years, are partly abandoned. This paper compares the new classes to the old ones. (orig.)

  9. Class, Culture and Politics

    DEFF Research Database (Denmark)

    Harrits, Gitte Sommer

    2013-01-01

    , discussions within political sociology have not yet utilized the merits of a multidimensional conception of class. In light of this, the article suggests a comprehensive Bourdieusian framework for class analysis, integrating culture as both a structural phenomenon co-constitutive of class and as symbolic...... practice. Further, the article explores this theoretical framework in a multiple correspondence analysis of a Danish survey, demonstrating how class and political practices are indeed homologous. However, the analysis also points at several elements of field autonomy, and the concluding discussion...

  10. A Case Study of Middle Class African American Males Taking Advanced Mathematics Classes in High School

    OpenAIRE

    Jones, Zella Higginbotham

    2011-01-01

    African American males in all socioeconomic levels are underperforming in school. Many researchers have conducted studies hoping to find reasons for the underperformance. This study focused on three middle class African American males in a suburban school district. These African American male students took upper level math courses that included Algebra III, Math Analysis, AP Calculus, and AP Statistics. This study modeled the study by E. Wayne Harris. He believed students were influenced...

  11. Calculus III essentials

    CERN Document Server

    REA, Editors of

    2012-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Calculus III includes vector analysis, real valued functions, partial differentiation, multiple integrations, vector fields, and infinite series.

  12. Implementace Basel III

    OpenAIRE

    Sychra, Pavel

    2014-01-01

    The aim of bachelor thesis is to introduce counterparty risk as one of the main risks, which the banks are exposed to. There is a decription of regulation and opinions of the expert community on its necessity in the thesis. The thesis includes characterization of institutions, which are connected to Basel frameworks, summary of standards Basel I and Basel II and especially new regulatory framework Basel III. This particular standard comprises new revision of capital charge for counterparty ri...

  13. 41 CFR 301-10.183 - What class of ship accommodations must I use?

    Science.gov (United States)

    2010-07-01

    ... Regulation System TEMPORARY DUTY (TDY) TRAVEL ALLOWANCES ALLOWABLE TRAVEL EXPENSES 10-TRANSPORTATION EXPENSES... duration of the special accommodation; and (iii) A recommendation as to the suitable class of... internal procedures pursuant to § 301-70.102(i). Transit Systems...

  14. Teaching Large Evening Classes

    Science.gov (United States)

    Wambuguh, Oscar

    2008-01-01

    High enrollments, conflicting student work schedules, and the sheer convenience of once-a-week classes are pushing many colleges to schedule evening courses. Held from 6 to 9 pm or 7 to 10 pm, these classes are typically packed, sometimes with more than 150 students in a large lecture theater. How can faculty effectively teach, control, or even…

  15. Class in disguise

    DEFF Research Database (Denmark)

    Faber, Stine Thidemann; Prieur, Annick

    This paper asks how class can have importance in one of the worlds’ most equal societies: Denmark. The answer is that class here appears in disguised forms. The field under study is a city, Aalborg, in the midst of transition from a stronghold of industrialism to a post industrial economy...

  16. Teaching Social Class

    Science.gov (United States)

    Tablante, Courtney B.; Fiske, Susan T.

    2015-01-01

    Discussing socioeconomic status in college classes can be challenging. Both teachers and students feel uncomfortable, yet social class matters more than ever. This is especially true, given increased income inequality in the United States and indications that higher education does not reduce this inequality as much as many people hope. Resources…

  17. DEFINING THE MIDDLE CLASS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Classifying the middle class remains controversial despite its alleged growth China’s cities housed more than 230 million middle-class residents in 2009 or 37 percent of the urban population,according to the 2011 Blue Book of Cities in China released on August 3.

  18. Separation of Am(III), Cm(III), and Cf(III) using capillary electrophoresis

    International Nuclear Information System (INIS)

    Trivalent actinides Am(III), Cm(III), and Cf(III) were successfully separated for the first time using capillary electrophoresis in 2-hydroxyisobutyric acid/acetic acid. It was found that the ionic radius was primarily important for separation of trivalent actinides as well as lanthanides in this condition. The stability constants of the Am(III) complexes with 2-hydroxyisobutyrate were estimated using the correlations between the molar fraction ratio of lanthanides and their ionic radii. (orig.)

  19. Comparisons of ASME-code fatigue-evaluation methods for nuclear Class 1 piping with Class 2 or 3 piping

    International Nuclear Information System (INIS)

    The fatigue evaluation procedure used in the ASME Boiler and Pressure Vessel Code, Sect. III, Nuclear Power Plant Components, for Class 1 piping is different from the procedure used for Class 2 or 3 piping. The basis for each procedure is described, and correlations between the two procedures are presented. Conditions under which either procedure or both may be unconservative are noted. Potential changes in the Class 2 or 3 piping procedure to explicitly cover all loadings are discussed. However, the report is intended to be informative, and while the contents of the report may guide future Code changes, specific recommendations are not given herein

  20. Genetics Home Reference: mucopolysaccharidosis type III

    Science.gov (United States)

    ... Understand Genetics Home Health Conditions mucopolysaccharidosis type III mucopolysaccharidosis type III Enable Javascript to view the expand/ ... boxes. Print All Open All Close All Description Mucopolysaccharidosis type III (MPS III), also known as Sanfilippo ...

  1. Social Class Dialogues and the Fostering of Class Consciousness

    Science.gov (United States)

    Madden, Meredith

    2015-01-01

    How do critical pedagogies promote undergraduate students' awareness of social class, social class identity, and social class inequalities in education? How do undergraduate students experience class consciousness-raising in the intergroup dialogue classroom? This qualitative study explores undergraduate students' class consciousness-raising in an…

  2. POPULATION III HYPERNOVAE

    Energy Technology Data Exchange (ETDEWEB)

    Smidt, Joseph; Whalen, Daniel J. [T-2, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Wiggins, Brandon K. [Department of Physics and Astronomy, Brigham Young University, Provo, UT 84602 (United States); Even, Wesley; Fryer, Chris L. [CCS-2, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Johnson, Jarrett L., E-mail: dwhalen1999@gmail.com [XTD-PRI, Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)

    2014-12-20

    Population III supernovae have been of growing interest of late for their potential to directly probe the properties of the first stars, particularly the most energetic events that are visible near the edge of the observable universe. Until now, hypernovae, the unusually energetic Type Ib/c supernovae that are sometimes associated with gamma-ray bursts, have been overlooked as cosmic beacons at the highest redshifts. In this, the latest of a series of studies on Population III supernovae, we present numerical simulations of 25-50 M {sub ☉} hypernovae and their light curves done with the Los Alamos RAGE and SPECTRUM codes. We find that they will be visible at z = 10-15 to the James Webb Space Telescope and z = 4-5 to the Wide-Field Infrared Survey Telescope, tracing star formation rates in the first galaxies and at the end of cosmological reionization. If, however, the hypernova crashes into a dense shell ejected by its progenitor, it is expected that a superluminous event will occur that may be seen at z ∼ 20 in the first generation of stars.

  3. Teaching Heterogeneous Classes.

    Science.gov (United States)

    Millrood, Radislav

    2002-01-01

    Discusses an approach to teaching heterogeneous English-as-a-Second/Foreign-Language classes. Draws on classroom research data to describe the features of a success-building lesson context. (Author/VWL)

  4. IELP Class Observation

    Institute of Scientific and Technical Information of China (English)

    陈了了

    2010-01-01

    @@ As an exchange student majoring in English, I am curious about how English is taught to international students here in America. Therefore, I observed an IELP (Intensive English Learning Program) class in Central Connecticut State University where I study.

  5. PSYCH 515 Complete Class

    OpenAIRE

    admin

    2015-01-01

      PSYCH 515 Advanced Abnormal Psychology To purchase this material click on below link http://www.assignmentcloud.com/PSYCH-515/PSYCH-515-Complete-Class-Guide For more details www.assignmentcloud.com

  6. Raradox of class description

    Institute of Scientific and Technical Information of China (English)

    吕光

    2004-01-01

    We have a more active class atmophere, but more passive self-study situations. We are too talktive when we should bury ourselves in books, but too less efficient when we spend too much time. We complain teachers

  7. Nordic Walking Classes

    CERN Multimedia

    Fitness Club

    2015-01-01

    Four classes of one hour each are held on Tuesdays. RDV barracks parking at Entrance A, 10 minutes before class time. Spring Course 2015: 05.05/12.05/19.05/26.05 Prices 40 CHF per session + 10 CHF club membership 5 CHF/hour pole rental Check out our schedule and enroll at: https://espace.cern.ch/club-fitness/Lists/Nordic%20Walking/NewForm.aspx? Hope to see you among us! fitness.club@cern.ch

  8. Embodying class and gender

    OpenAIRE

    Geers, Alexie

    2015-01-01

    In March 1937, when the first issue of Marie-Claire was published, the images of the female body it presented to its female readers from working-class backgrounds contrasted sharply with those featured in previous magazines. The female bodies are dressed and groomed to seduce and replace the hieratic bodies that presented fashions synonymous with membership in the upper classes. The present essay examines this shift and shows that the visual repertoire employed is borrowed from that of the fe...

  9. Generalized Fourier transforms classes

    DEFF Research Database (Denmark)

    Berntsen, Svend; Møller, Steen

    2002-01-01

    The Fourier class of integral transforms with kernels $B(\\omega r)$ has by definition inverse transforms with kernel $B(-\\omega r)$. The space of such transforms is explicitly constructed. A slightly more general class of generalized Fourier transforms are introduced. From the general theory foll...... follows that integral transform with kernels which are products of a Bessel and a Hankel function or which is of a certain general hypergeometric type have inverse transforms of the same structure....

  10. Teaching groundwater dynamics: connecting classroom to practical and field classes

    Science.gov (United States)

    Hakoun, V.; Mazzilli, N.; Pistre, S.; Jourde, H.

    2013-01-01

    Preparing future hydrogeologists to provide inputs in societal discussions in a changing world is a challenging task that induces a need for efficient teaching frameworks. The educational literature suggests that hydrogeology courses should consistently integrate classroom instruction with practical and field classes. However, most teaching examples still separate these three class components. This paper presents an introductory course to groundwater dynamics taught at the Université des Sciences de Montpellier, France. The adopted pedagogical scheme and the proposed activities are described in details. The key points of the proposed course are: (i) an educational scheme that iteratively links groundwater dynamics topics to the three class components, (ii) a course that is structured around a main thread (well testing) called in each class component, (iii) a pedagogical approach that promotes active learning strategies, in particular using original practical classes and field experiments. The experience indicates that the proposed scheme improves the learning process, as compared to a classical, teacher-centered approach.

  11. [Diagnosis and therapy of adult patients with facial asymmetry].

    Science.gov (United States)

    Takano-Yamamoto, Teruko; Kuroda, Shingo

    2009-09-01

    The goal of orthodontic treatment is to improve the patient's life by enhancing dental and jaw functions and dentofacial esthetics [Graber TM, et al., Orthodontics current principles and techniques. 4(e) ed. St Louis: Elsevier, 2005.]. Harmonious occlusion is achieved following improvements of malocclusion via orthodontic treatment [Ehmer U and Broll P, Int J Adult Orthod Orthognath Surg 1992;7:153-159. Throckmorton GS, et al., J Prosthet Dent 1984;51:252-261.]. Perfect facial symmetry is extremely rare, and normal faces have a degree of asymmetry. Patients with dentofacial deformity more frequently have asymmetry of the face and jaws. There was a relationship between the type of malocclusion and the prevalence of asymmetry; 28% of the Class III group, but 40% to 42% of the Class I, Class II and long face groups respectively, were asymmetric [Severt TR and Proffit WR, Int J Adult Orthod Orthogn Surg 1997;12:171-176.]; therefore, facial asymmetry is a common complaint among orthodontic patients. Treatment of severe facial asymmetry in adults consists mainly of surgically repositioning the maxilla or the mandible [Bardinet E, et al., Orthod Fr 2002;73:243-315. Guyuron B, Clin Plast Surg 1989;16:795-801. Proffit WR, et al., Contemporary treatment of dentofacial deformity. 2003. St Louis: Mosby, 2003:574-644.], however, new methods, i.e. orthodontic tooth movement with implant anchorage, have recently been introduced [Costa A, et al., Int J Adult Orthod Orthognath Surg 1998;3:201-209. Creekmore TD and Eklund MK, J Clin Orthod 1983;17:266-269. Miyawaki S,et al., Am J Orthod Dentofacial Orthop 2003;124:373-378. Park HS, et al., J Clin Orthod 2001;35:417-422. Roberts WE, et al., Angle Orthod 1989;59:247-256.], and various treatment options can be chosen in patients with facial asymmetry. In this article, we describe the diagnosis and treatment of adult patients with facial asymmetry. PMID:19726025

  12. Ammonium diphosphitoindate(III

    Directory of Open Access Journals (Sweden)

    Farida Hamchaoui

    2013-04-01

    Full Text Available The crystal structure of the title compound, NH4[In(HPO32], is built up from InIII cations (site symmetry 3m. adopting an octahedral environment and two different phosphite anions (each with site symmetry 3m. exhibiting a triangular–pyramidal geometry. Each InO6 octahedron shares its six apices with hydrogen phosphite groups. Reciprocally, each HPO3 group shares all its O atoms with three different metal cations, leading to [In(HPO32]− layers which propagate in the ab plane. The ammonium cation likewise has site symmetry 3m.. In the structure, the cations are located between the [In(HPO32]− layers of the host framework. The sheets are held together by hydrogen bonds formed between the NH4+ cations and the O atoms of the framework.

  13. Semiconducting III-V compounds

    CERN Document Server

    Hilsum, C; Henisch, Heinz R

    1961-01-01

    Semiconducting III-V Compounds deals with the properties of III-V compounds as a family of semiconducting crystals and relates these compounds to the monatomic semiconductors silicon and germanium. Emphasis is placed on physical processes that are peculiar to III-V compounds, particularly those that combine boron, aluminum, gallium, and indium with phosphorus, arsenic, and antimony (for example, indium antimonide, indium arsenide, gallium antimonide, and gallium arsenide).Comprised of eight chapters, this book begins with an assessment of the crystal structure and binding of III-V compounds, f

  14. Human RNA Polymerase III transcriptomes and relationships to Pol II promoters, enhancer-binding factors and chromatin domains

    OpenAIRE

    Oler, Andrew J.; Alla, Ravi K.; Roberts, Douglas N.; Wong, Alexander; Hollenhorst, Peter C.; Chandler, Katherine J.; Cassiday, Patrick A.; Nelson, Cassie A.; Hagedorn, Curt H.; Graves, Barbara J.; Cairns, Bradley R

    2010-01-01

    RNA polymerase (Pol) III transcribes many noncoding RNAs (e.g. tRNAs) important for translational capacity and other functions. Here, we localized Pol III, alternative TFIIIB complexes (BRF1/2) and TFIIIC in HeLa cells, determining the Pol III transcriptome, defining gene classes, and revealing ‘TFIIIC-only’ sites. Pol III localization in other transformed and primary cell lines revealed novel and cell-type specific Pol III loci, and one miRNA. Surprisingly, only a fraction of the in silico-p...

  15. theories of class

    Science.gov (United States)

    Gaiotto, Davide; Razamat, Shlomo S.

    2015-07-01

    We construct classes of superconformal theories elements of which are labeled by punctured Riemann surfaces. Degenerations of the surfaces correspond, in some cases, to weak coupling limits. Different classes are labeled by two integers ( N, k). The k = 1 case coincides with A N - 1 theories of class and simple examples of theories with k > 1 are orbifolds of some of the A N - 1 class theories. For the space of theories to be complete in an appropriate sense we find it necessary to conjecture existence of new strongly coupled SCFTs. These SCFTs when coupled to additional matter can be related by dualities to gauge theories. We discuss in detail the A 1 case with k = 2 using the supersymmetric index as our analysis tool. The index of theories in classes with k > 1 can be constructed using eigenfunctions of elliptic quantum mechanical models generalizing the Ruijsenaars-Schneider integrable model. When the elliptic curve of the model degenerates these eigenfunctions become polynomials with coefficients being algebraic expressions in fugacities, generalizing the Macdonald polynomials with rational coefficients appearing when k = 1.

  16. Does class attendance still matter?

    OpenAIRE

    Abel Nyamapfene

    2010-01-01

    This paper presents a study on the impact of class attendance on academic performance in a second year Electronics Engineering course module with online notes and no mandatory class attendance policy. The study shows that class attendance is highly correlated to academic performance, despite the availability of online class notes. In addition, there is significant correlation between class attendance and non-class contact with the lecturer and between student performance in the first year of ...

  17. Translation in ESL Classes

    Directory of Open Access Journals (Sweden)

    Nagy Imola Katalin

    2015-12-01

    Full Text Available The problem of translation in foreign language classes cannot be dealt with unless we attempt to make an overview of what translation meant for language teaching in different periods of language pedagogy. From the translation-oriented grammar-translation method through the complete ban on translation and mother tongue during the times of the audio-lingual approaches, we have come today to reconsider the role and status of translation in ESL classes. This article attempts to advocate for translation as a useful ESL class activity, which can completely fulfil the requirements of communicativeness. We also attempt to identify some activities and games, which rely on translation in some books published in the 1990s and the 2000s.

  18. Complexes of 4-chlorophenoxyacetates of Nd(III), Gd(III) and Ho(III)

    International Nuclear Information System (INIS)

    The complexes of 4-chlorophenoxyacetates of Nd(III), Gd(III) and Ho(III) have been synthesized as polycrystalline hydrated solids, and characterized by elemental analysis, spectroscopy, magnetic studies and also by X-ray diffraction and thermogravimetric measurements. The analysed complexes have the following colours: violet for Nd(III), white for Gd(III) and cream for Ho(III) compounds. The carboxylate groups bind as bidentate chelating (Ho) or bridging ligands (Nd, Gd). On heating to 1173K in air the complexes decompose in several steps. At first, they dehydrate in one step to form anhydrous salts, that next decompose to the oxides of respective metals. The gaseous products of their thermal decomposition in nitrogen were also determined and the magnetic susceptibilities were measured over the temperature range of 76-303K and the magnetic moments were calculated. The results show that 4-chlorophenoxyacetates of Nd(III), Gd(III) and Ho(III) are high-spin complexes with weak ligand fields. The solubility value in water at 293K for analysed 4-chlorophenoxyacetates is in the order of 10-4mol/dm3. (author)

  19. Content of Pollonium 210 in tobacco leaves depending on their quality (class)

    International Nuclear Information System (INIS)

    Content of polonium 210 was studied in the leaves of six varieties of Bulgarian oriental tobacco according to their class. Tobacco that had to be examined was kept for more than three years for equilibrium between polonium 210 and lead 210 to be reached. Tobacco leaves of higher classes contained smaller quantities polonium 210 compared with those of lower classes (III-V classes). This is due to leaves of the upper and middle parts of the plant with a shorter vegetation period belonging to higher tobacco classes; radionuclide penetration by the root. The established divergence from this relationship was due to some other reasons such as mechanical damage, etc. (A.B.)

  20. BIO 315 Complete Class

    OpenAIRE

    admn

    2015-01-01

    BIO 315 Complete Class Check this A+ tutorial guideline at   http://www.assignmentcloud.com/BIO-315/BIO-315-Complete-Class BIO 315 Week 1 DQ 1 BIO 315 Week 1 DQ 2 BIO 315 Week 1 Individual Assignment Beren Robinson Field Study Paper BIO 315 Week 2 DQ 1 BIO 315 Week 2 DQ 2 BIO 315 Week 2 DQ 3 BIO 315 Week 2 Individual Assignment Environment Resources and Competition BIO 315 Week 2 Week Two Learning Team Exercises BIO 315 Week 3 DQ 1 BIO ...

  1. Class actions in Portugal

    OpenAIRE

    Raimundo, Maria Carlos Miranda

    2013-01-01

    Even eighteen years after the implementation of Law 83/95, of August 31, about the rights of participation in class action litigation in Portugal, there is no sufficient evidence of its applicability. Contrarily to what is observed in other countries as the United States and Brazil it seems that in Portugal, there is no interest of the several parties that would be involved in a class action litigation to obtain information or inform other parties relatively to the main procedures on it and t...

  2. An "expanded" class perspective

    DEFF Research Database (Denmark)

    Steur, Luisa Johanna

    2014-01-01

    Adivasis against their age-old colonization or the work of ‘external’ agitators. Capitalist restructuring and ‘globalization’ was generally seen as simply the latest chapter in the suffering of these Adivasis. Little focused attention was paid to the recent class trajectory of their lives under changing...... analysis, as elaborated in Marxian anthropology, this article provides an alternative to the liberal-culturalist explanation of indigenism in Kerala, arguing instead that contemporary class processes—as experienced close to the skin by the people who decided to participate in the Muthanga struggle...

  3. Talking Class in Tehroon

    DEFF Research Database (Denmark)

    Elling, Rasmus Christian; Rezakhani, Khodadad

    2016-01-01

    Persian, like any other language, is laced with references to class, both blatant and subtle. With idioms and metaphors, Iranians can identify and situate others, and thus themselves, within hierarchies of social status and privilege, both real and imagined. Some class-related terms can be traced...... back to medieval times, whereas others are of modern vintage, the linguistic legacy of television shows, pop songs, social media memes or street vernacular. Every day, it seems, an infectious set of phrases appears that make yesterday’s seem embarrassingly antiquated....

  4. Residues of Chern classes

    OpenAIRE

    Suwa, Tatsuo; 諏訪, 立雄

    2003-01-01

    If we have a finite number of sections of a complex vector bundle E over a manifold M, certain Chern classes of E are localized at the singular set S, i.e., the set of points where the sections fail to be linearly independent. When S is compact, the localizations define the residues at each connected component of S by the Alexander duality. If M itself is compact, the sum of the residues is equal to the Poincaré dual of the corresponding Chern class. This type of theory is also developed for ...

  5. Residues of Chern classes

    OpenAIRE

    Suwa, Tatsuo

    2003-01-01

    If we have a finite number of sections of a complex vector bundle $E$ over a manifold $M$ , certain Chern classes of $E$ are localized at the singular set $S$ , i.e., the set of points where the sections fail to be linearly independent. When $S$ is compact, the localizations define the residues at each connected component of $S$ by the Alexander duality. If $M$ itself is compact, the sum of the residues is equal to the Poincaré dual of the corresponding Chern class. This type of theory is als...

  6. Evaluation of the dental arch asymmetry in natural normal occlusion and Class II malocclusion individuals

    OpenAIRE

    Paulo Estevão Scanavini; Luiz Renato Paranhos; Fernando César Torres; Maria Helena Ferreira Vasconcelos; Renata Pilli Jóias; Marco Antonio Scanavini

    2012-01-01

    OBJECTIVE: To verify the presence and degree of asymmetry of dental arches in Brazilian individuals with natural normal occlusion and Class II, Divisions 1 and 2 malocclusions. METHODS: The study evaluated the symmetry of the maxillary and mandibular dental arches of 180 pairs of dental casts, divided into: Group I = 60 pairs of natural normal occlusion individuals; Group II = 60 pairs of Class II, Division 1 malocclusion individuals; and Group III = 60 pairs of Class II, Division 2 malocclus...

  7. Basel III and the Net Stable Funding Ratio

    OpenAIRE

    Gideon, F.; Petersen, Mark A.; Janine Mukuddem-Petersen; LNP Hlatshwayo

    2013-01-01

    We validate the new Basel liquidity standards as encapsulated by the net stable funding ratio in a quantitative manner. In this regard, we consider the dynamics of inverse net stable funding ratio as a measure to quantify the bank’s prospects for a stable funding over a period of a year. In essence, this justifies how Basel III liquidity standards can be effectively implemented in mitigating liquidity problems. We also discuss various classes of available stable funding and required stable fu...

  8. ROSA-III system description

    International Nuclear Information System (INIS)

    The ROSA-III system and its instrumentations are described. The informations are necessary to understand and analyze the experimental data obtained from loss-of-coolant experiments (LOCEs) conducted in the ROSA (Rig of Safety Assessment)-III facility. (author)

  9. Design of a class 1 safety valve

    International Nuclear Information System (INIS)

    Spring-loaded safety valves are used to protect the over-pressurization of fluid systems or pressure vessels. The valves are required to open for the pressure mitigation and reseat after the system pressure is reduced to a certain value. Due to its critical role in power plants, the structural integrity of the valve is highly demanded. In nuclear power application, the design of the valve is required to comply with the provisions in the codes and standards. In many countries, nuclear service safety valves are designed to the requirements of ASME Section III. In Korea, KEPIC (Korea Electric Power Industry Code) as well as ASME Section III is accepted as the standards for the design and manufacturing of nuclear equipment as specified in the Notice No. 2000-17 of the MOST (Ministry of Science and Technology). To date, the maintenance of safety related valves has been principally relied on by overseas technology, if significant failure was found during the valve operation. This is mainly due to the fact that nuclear service safety valves were not developed domestically until a recent date. In the last two years, KEPRI has developed a MSSV (Main Steam Safety Valve) in cooperation with Jokwang I.L.I. Co. In the design process, the structural adequacy of the valve was assessed as a safety Class 1 valve by principally relying on the FE (Finite Element) technique. Actually, the valve can be designed to the requirement of a Class 2 valve. In spite of the industrial interest, there are few design materials which could be referred to. Therefore, delineation of a design procedure for nuclear equipment is claimed. To this end, the assessment procedure for the safety valve structure is discussed in the present study based on KEPIC MNB (or ASME Section III NB)

  10. Teaching Very Large Classes

    Science.gov (United States)

    DeRogatis, Amy; Honerkamp, Kenneth; McDaniel, Justin; Medine, Carolyn; Nyitray, Vivian-Lee; Pearson, Thomas

    2014-01-01

    The editor of "Teaching Theology and Religion" facilitated this reflective conversation with five teachers who have extensive experience and success teaching extremely large classes (150 students or more). In the course of the conversation these professors exchange and analyze the effectiveness of several active learning strategies they…

  11. Reference class forecasting

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    Underbudgettering og budgetoverskridelser forekommer i et flertal af større bygge- og anlægsprojekter. Problemet skyldes optimisme og/eller strategisk misinformation i budgetteringsprocessen. Reference class forecasting (RCF) er en prognosemetode, som er udviklet for at reducere eller eliminere...

  12. Fostering a Middle Class

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Though there is no official definition of "middle class" in China, the tag has become one few Chinese people believe they deserve anyway.In early August, the Chinese Academy of Social Sciences released a report on China’s urban development,

  13. Second class weak currents

    International Nuclear Information System (INIS)

    The definition and general properties of weak second class currents are recalled and various detection possibilities briefly reviewed. It is shown that the existing data on nuclear beta decay can be consistently analysed in terms of a phenomenological model. Their implication on the fundamental structure of weak interactions is discussed

  14. Class Actions in Denmark

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2009-01-01

    The article deals with the relatively new Danish Act on Class Action (Danish: gruppesøgsmål) which was suggested by The Permanent Council on Civil procedure (Retsplejerådet) of which the article's author is a member. The operability of the new provisions is illustrated through some wellknown Danish...

  15. Adeus à classe trabalhadora?

    Directory of Open Access Journals (Sweden)

    Geoff Eley

    2013-12-01

    Full Text Available No início da década de 1980, a política centrada em classes da tradição socialista estava em crise, e comentadores importantes adotaram tons apocalípticos. No final da década, a esquerda permanecia profundamente dividida entre os advogados da mudança e os defensores da fé. Em meados dos anos 1990, os primeiros tinham, de modo geral, ganhado a batalha. O artigo busca apresentar essa mudança contemporânea não como a 'morte da classe', mas como o desa­parecimento de um tipo particular de ­sociedade de classes, marcado pelo ­processo de formação da classe trabalhadora entre os anos 1880 e 1940 e pelo alinhamento político daí resultante, atingindo seu apogeu na construção social-democrata do acordo do pós-guerra. Quando mudanças de longo prazo na economia se combinaram com o ataque ao keynesianismo na política de recessão a partir de meados da década de 1970, a unidade da classe trabalhadora deixou de estar disponível da forma antiga e bastante utilizada, como o terreno natural da política de esquerda. Enquanto uma coletividade dominante da classe trabalhadora entrou em declínio, outra se corporificou de modo lento e desigual para tomar o lugar daquela. Mas a unidade operacional dessa nova agregação da classe trabalhadora ainda está, em grande parte, em formação. Para recuperar a eficácia política da tradição socialista, alguma nova visão de agência política coletiva será necessária, uma visão imaginativamente ajustada às condições emergentes da produção e acumulação capitalista no início do século XXI.

  16. Genomic Characterization of Methanomicrobiales Reveals Three Classes of Methanogens

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Iain; Ulrich, Luke E.; Lupa, Boguslaw; Susanti, Dwi; Porat, Iris; Hooper, Sean D.; Lykidis, Athanasios; Sieprawska-Lupa, Magdalena; Dharmarajan, Lakshmi; Goltsman, Eugene; Lapidus, Alla; Saunders, Elizabeth; Han, Cliff; Land, Miriam; Lucas, Susan; Mukhopadhyay, Biswarup; Whitman, William B.; Woese, Carl; Bristow, James; Kyrpides, Nikos

    2009-05-01

    Methanomicrobiales is the least studied order of methanogens. While these organisms appear to be more closely related to the Methanosarcinales in ribosomal-based phylogenetic analyses, they are metabolically more similar to Class I methanogens. In order to improve our understanding of this lineage, we have completely sequenced the genomes of two members of this order, Methanocorpusculum labreanum Z and Methanoculleus marisnigri JR1, and compared them with the genome of a third, Methanospirillum hungatei JF-1. Similar to Class I methanogens, Methanomicrobiales use a partial reductive citric acid cycle for 2-oxoglutarate biosynthesis, and they have the Eha energy-converting hydrogenase. In common with Methanosarcinales, Methanomicrobiales possess the Ech hydrogenase and at least some of them may couple formylmethanofuran formation and heterodisulfide reduction to transmembrane ion gradients. Uniquely, M. labreanum and M. hungatei contain hydrogenases similar to the Pyrococcus furiosus Mbh hydrogenase, and all three Methanomicrobiales have anti-sigma factor and anti-anti-sigma factor regulatory proteins not found in other methanogens. Phylogenetic analysis based on seven core proteins of methanogenesis and cofactor biosynthesis places the Methanomicrobiales equidistant from Class I methanogens and Methanosarcinales. Our results indicate that Methanomicrobiales, rather than being similar to Class I methanogens or Methanomicrobiales, share some features of both and have some unique properties. We find that there are three distinct classes of methanogens: the Class I methanogens, the Methanomicrobiales (Class II), and the Methanosarcinales (Class III).

  17. New complexes of samarium(III), terbium(III) and holmium (III) with quercetin-5'-sulfonic acid

    International Nuclear Information System (INIS)

    New solid complexes of samarium(III), terbium (III), and holmium (III) with quercetin-5'-sulfonic acid were obtained. Their composition and physicochemical properties were investigated. Ultraviolet, visible and infrared spectroscopy methods were used to determine their structure. (author)

  18. PREFACE: Quantum Optics III

    Science.gov (United States)

    Orszag, M.; Retamal, J. C.; Saavedra, C.; Wallentowitz, S.

    2007-06-01

    All the 50 years of conscious pondering did not bring me nearer to an answer to the question `what is light quanta?'. Nowadays, every rascal believes, he knows it, however, he is mistaken. (A Einstein, 1951 in a letter to M Besso) Quantum optics has played a key role in physics in the last several decades. On the other hand, in these early decades of the information age, the flow of information is becoming more and more central to our daily life. Thus, the related fields of quantum information theory as well as Bose-Einstein condensation have acquired tremendous importance in the last couple of decades. In Quantum Optics III, a fusion of these fields appears in a natural way. Quantum Optics III was held in Pucón, Chile, in 27-30 of November, 2006. This beautiful location in the south of Chile is near the lake Villarrica and below the snow covered volcano of the same name. This fantastic environment contributed to a relaxed atmosphere, suitable for informal discussion and for the students to have a chance to meet the key figures in the field. The previous Quantum Optics conferences took place in Santiago, Chile (Quantum Optics I, 2000) and Cozumel, Mexico (Quantum Optics II, 2004). About 115 participants from 19 countries attended and participated in the meeting to discuss a wide variety of topics such as quantum-information processing, experiments related to non-linear optics and squeezing, various aspects of entanglement including its sudden death, correlated twin-photon experiments, light storage, decoherence-free subspaces, Bose-Einstein condensation, discrete Wigner functions and many more. There was a strong Latin-American participation from Argentina, Brazil, Chile, Colombia, Peru, Uruguay, Venezuela and Mexico, as well as from Europe, USA, China, and Australia. New experimental and theoretical results were presented at the conference. In Latin-America a quiet revolution has taken place in the last twenty years. Several groups working in quantum optics and

  19. Juvenile idiopathic arthritis (JIA): a screening study to measure class II skeletal pattern, TMJ PDS and use of systemic corticosteroids.

    LENUS (Irish Health Repository)

    Mandall, Nicky A

    2010-03-01

    To screen patients with oligoarticular and polyarticular forms of Juvenile Idiopathic Arthritis (JIA) to determine (i) the severity of their class II skeletal pattern; (ii) temporomandibular joint signs and symptoms and (iii) use of systemic corticosteroids.

  20. Basel III D: Swiss Finish to Basel III

    OpenAIRE

    Christian M. McNamara; Natalia Tente; Andrew Metrick

    2014-01-01

    After the Basel Committee on Banking Supervision (BCBS) introduced the Basel III framework in 2010, individual countries confronted the question of how best to implement the framework given their unique circumstances.  Switzerland, with a banking industry that is both heavily concentrated and very large relative to the size of its overall economy, faced a special challenge.  It ultimately adopted what is sometimes referred to as the “Swiss Finish” to Basel III – enhanced requirements applicab...

  1. Generation III+ Reactor Portfolio

    International Nuclear Information System (INIS)

    While the power generation needs of utilities are unique and diverse, they are all faced with the double challenge of meeting growing electricity needs while curbing CO2 emissions. To answer these diverse needs and help tackle this challenge, AREVA has developed several reactor models which are briefly described in this document: The EPRTM Reactor: designed on the basis of the Konvoi (Germany) and N4 (France) reactors, the EPRTM reactor is an evolutionary model designed to achieve best-in-class safety and operational performance levels. The ATMEA1TM reactor: jointly designed by Mitsubishi Heavy Industries and AREVA through ATMEA, their common company. This reactor design benefits from the competencies and expertise of the two mother companies, which have commissioned close to 130 reactor units. The KERENATM reactor: Designed on the basis of the most recent German BWR reactors (Gundremmingen) the KERENATM reactor relies on proven technology while also including innovative, yet thoroughly tested, features. The optimal combination of active and passive safety systems for a boiling water reactor achieves a very low probability of severe accident

  2. Flexible Word Classes

    DEFF Research Database (Denmark)

    van Lier, Eva; Rijkhoff, Jan

    2013-01-01

    • First major publication on the phenomenon • Offers cross-linguistic, descriptive, and diverse theoretical approaches • Includes analysis of data from different language families and from lesser studied languages This book is the first major cross-linguistic study of 'flexible words', i.e. words...... that cannot be classified in terms of the traditional lexical categories Verb, Noun, Adjective or Adverb. Flexible words can - without special morphosyntactic marking - serve in functions for which other languages must employ members of two or more of the four traditional, 'specialised' word classes....... Thus, flexible words are underspecified for communicative functions like 'predicating' (verbal function), 'referring' (nominal function) or 'modifying' (a function typically associated with adjectives and e.g. manner adverbs). Even though linguists have been aware of flexible world classes for more...

  3. Class Attendance and Academic Performance among Spanish Economics Students

    OpenAIRE

    Velasco, Carlos; D´Addazio, Rosaria; Andrietti, Vincenzo

    2008-01-01

    This paper presents new evidence on the effects of class attendance on academic performance. We analyse survey data collected for an Introductory Econometrics Course at the Facultad de Ciencias Sociales y Jurídicas of Universidad Carlos III de Madrid, matched to administrative data. Using OLS-proxy regressions to control for unobservable student characteristics potentially correlated with attendance, we find a positive and significant effect of attendance on academic performance. However, the...

  4. Class Action and Class Settlement in a European Perspective

    DEFF Research Database (Denmark)

    Werlauff, Erik

    2013-01-01

    The article analyses the options for introducing common European rules on class action lawsuits with an opt-out-model in individual cases. An analysis is made of how the risks of misuse of class actions can be prevented. The article considers the Dutch rules on class settlements (the WCAM procedure...

  5. Extraction of Am(III) and Eu(III) by 2,6-di(5,6-dialkyl-1,2,4-triazine-3-yl)pyridines

    International Nuclear Information System (INIS)

    It had previously been shown that 2,6-di(5,6-dialkyl-1,2,4-triazine-3-yl)pyridines extract Am(III) selectively over Eu(III), giving a separation factor of 100-120. In this work a more detailed study of the distribution equilibria was made. If not given otherwise, 2,6-di(5,6-di-propyl-1,2,4-triazine-3-yl)pyridine (=B) was taken as a representative of the title extractant class and a mixture of branched alkanes (TPH) modified with 2-ethyl-1-hexanol was taken as a diluent. Since Am(III) and Eu(III) (=M) are extracted as complexes of the type M(NO3)33B, their distribution ratios increase strongly with the activity of nitrate ions in the aqueous phase and the concentration of the extractant in the organic phase. The distribution ratios of the metals are suppressed in the presence of macro amounts of Eu(III), due to lowering the free extractant concentration as the solvent loading is not negligible, but the Am(III)/Eu(III) separation factor remains unchanged. The extraction of Am(III) and Eu(III) is little changed if 1-octanol is taken as a TPH modifier instead of 2-ethyl-1-hexanol, and the highest distribution ratios are attained at 10-20 vol% alcohol. The optimum concentration of the alcohol is 20 vol%, giving appropriate solubilization of the extractant in the mixed diluent. Higher distribution ratios are obtained in the presence of 1-butanol which, however, solubilizes the extractant less effectively than the octanols. Both the extraction efficiency and the Am(III)/Eu(III) separation factor decrease in the following order of diluents (each modified by 20 vol% 2-ethyl-1-hexanol): TPH > cyclohexane > 2-methyl-4-pentanone > 2-ethylhexyl acetate > chloro-benzene > benzene > xylene. (author)

  6. GBM 489 Complete Class

    OpenAIRE

    admn

    2015-01-01

    GBM 489 Complete Class Check this A+ tutorial guideline at   http://www.assignmentcloud.com/GBM-489/GBM-489-Strategic-Topics-in-Global-Business-Management GBM 489 Strategic Topics in Global Business Management GBM 489 Week 1 DQ 1 GBM 489 Week 1 DQ 2 GBM 489 Week 1 DQ 3 GBM 489 Week 1 Individual Global Trends Paper GBM 489 Week 2 DQ 1 GBM 489 Week 2 DQ 2 GBM 489 Week 2 DQ 3 GBM 489 Week 2 Individual Business Plan Article Analysis GBM 489...

  7. The Class of '34

    OpenAIRE

    Cairney, Richard

    1995-01-01

    The Great Depression raged, governments were beleaguered, the unemployment rate stood at 30%, scurvy stalked the poor and no one was immune to contagious diseases such as scarlet fever, polio and measles when the University of Alberta School of Medicine's Class of '34 graduated. For four alumni who recently gathered in Edmonton—Drs. Morley Hodgson, Melvin Gaudin, John McLurg and Edmund Cairns—their 60th-anniversary reunion was a time to recall the changes they have witnessed in medicine, incl...

  8. Mining Java Class Naming Conventions

    OpenAIRE

    Butler, Simon; Wermelinger, Michel; Yu, Yijun; Sharp, Helen

    2011-01-01

    Class names represent the concepts implemented in object-oriented source code and are key elements in program comprehension and, thus, software maintenance. Programming conventions often state that class names should be noun-phrases, but there is little further guidance for developers on the composition of class names. Other researchers have observed that the majority of Java class identifier names are composed of one or more nouns preceded, optionally, by one or more adjectives. However, no ...

  9. Syntactic classes of subordinate clauses in German

    Directory of Open Access Journals (Sweden)

    Hardarik Blühdorn

    2013-06-01

    Full Text Available O artigo dá uma visão panorâmica das classes de orações subordinadas da língua alemã. Suas funções e estruturas sintáticas são descritas mediante o esquema das posições e dos campos. Três aspectos específicos são tratados mais a fundo: as funções (i de pronomes e (ii de partículas de comparação em relação a orações subordinadas e (iii o papel de orações subordinadas em construções clivadas. O artigo pode ser usado para fins didáticos no meio acadêmico e como ponto de partida para estudos em sintaxe comparativa.

  10. URBAN AND REGIONAL CREATIVE CLASS THEORIES

    OpenAIRE

    Tremblay, Remy; CHICOINE, Huges

    2011-01-01

    The creative class theory suggests that society is composed of three social classes: the creative class, the service class, the working class, a different view or classification of the workforce. The boundaries separating the creative class from the upper ruling class and the lower working class rest on occupational premises. This paper examines the construction and tools of the creative class, its human composition as a social class, attending discourses, as well as the shifting foundations ...

  11. Teachers, Social Class and Underachievement

    Science.gov (United States)

    Dunne, Mairead; Gazeley, Louise

    2008-01-01

    Addressing the "the social class attainment gap" in education has become a government priority in England. Despite multiple initiatives, however, little has effectively addressed the underachievement of working-class pupils within the classroom. In order to develop clearer understandings of working-class underachievement at this level, this small…

  12. III-Nitride nanowire optoelectronics

    Science.gov (United States)

    Zhao, Songrui; Nguyen, Hieu P. T.; Kibria, Md. G.; Mi, Zetian

    2015-11-01

    Group-III nitride nanowire structures, including GaN, InN, AlN and their alloys, have been intensively studied in the past decade. Unique to this material system is that its energy bandgap can be tuned from the deep ultraviolet (~6.2 eV for AlN) to the near infrared (~0.65 eV for InN). In this article, we provide an overview on the recent progress made in III-nitride nanowire optoelectronic devices, including light emitting diodes, lasers, photodetectors, single photon sources, intraband devices, solar cells, and artificial photosynthesis. The present challenges and future prospects of III-nitride nanowire optoelectronic devices are also discussed.

  13. Understanding Class in Contemporary Societies

    DEFF Research Database (Denmark)

    Harrits, Gitte Sommer

    In this paper, I argue that claims about the death of class and the coming of the classless society are premature. Such claims are seldom genuinely empirical, and the theoretical argument often refers to a simple and therefore easily dismissible concept of class. By rejecting the concept of class...... altogether, sociological theory runs the risk of loosing the capacity for analysing stratification and vertical differentiation of power and freedom, which in late modernity seem to be a of continuing importance. Hence, I argue that although class analysis faces a number of serious challenges, it is possible...... to reinvent class analysis. The sociology of Pierre Bourdieu in many ways introduces an appropriate paradigm, and the paper therefore critically discusses Bourdieu's concept of class. Since the "Bourdieuan" class concept is primarily epistemological, i.e. a research strategy more than a theory...

  14. Trigger efficiencies at BES III

    CERN Document Server

    Berger, N; Liu, Z A; Jin, D P; Xu, H; Gong, W X; Wang, K; Cao, G F

    2010-01-01

    Trigger efficiencies at BES III were determined for both the J/psi and psi' data taking of 2009. Both dedicated runs and physics datasets are used; efficiencies are presented for Bhabha-scattering events, generic hadronic decay events involving charged tracks, dimuon events and psi' -> pi+pi-J/psi, J/psi -> l+l- events (l an electron or muon). The efficiencies are found to lie well above 99% for all relevant physics cases, thus fulfilling the BES III design specifications.

  15. Graphics Gems III IBM version

    CERN Document Server

    Kirk, David

    1994-01-01

    This sequel to Graphics Gems (Academic Press, 1990), and Graphics Gems II (Academic Press, 1991) is a practical collection of computer graphics programming tools and techniques. Graphics Gems III contains a larger percentage of gems related to modeling and rendering, particularly lighting and shading. This new edition also covers image processing, numerical and programming techniques, modeling and transformations, 2D and 3D geometry and algorithms,ray tracing and radiosity, rendering, and more clever new tools and tricks for graphics programming. Volume III also includes a

  16. Migrations of the Creative Class: Evidence from Sweden

    DEFF Research Database (Denmark)

    Hansen, Høgni Kalsø; Niedomysl, Thomas

    2009-01-01

    A central element in contemporary regional development strategies is the ability for regions to attract and retain talented people. The underlying argument is that by attracting talented people, regions are better geared to meet the demand of competences of the knowledge economy and become more...... competitive. This article focuses on the migration of the creative class in Sweden. Three questions, central to recent theoretical claims but until now overlooked, are addressed: (i) Do members of the creative class move more often compared to other migrant groups? (ii) Are they more selective in their...... destination choices, favouring regions with a favourable ‘people climate’? (iii) Do their reasons for migration differ from those of other migrant groups? Employing unique Swedish survey and register data, the results show that the migration rates of the creative class are only marginally higher than for...

  17. Group III metabotropic glutamate receptors and drug addiction.

    Science.gov (United States)

    Mao, Limin; Guo, Minglei; Jin, Daozhong; Xue, Bing; Wang, John Q

    2013-12-01

    Neuroadaptations of glutamatergic transmission in the limbic reward circuitry are linked to persistent drug addiction. Accumulating data have demonstrated roles of ionotropic glutamate receptors and group I and II metabotropic glutamate receptors (mGluRs) in this event. Emerging evidence also identifies Gαi/o-coupled group III mGluRs (mGluR4/7/8 subtypes enriched in the limbic system) as direct substrates of drugs of abuse and active regulators of drug action. Auto- and heteroreceptors of mGluR4/7/8 reside predominantly on nerve terminals of glutamatergic corticostriatal and GABAergic striatopallidal pathways, respectively. These presynaptic receptors regulate basal and/or phasic release of respective transmitters to maintain basal ganglia homeostasis. In response to operant administration of common addictive drugs, such as psychostimulants (cocaine and amphetamine), alcohol and opiates, limbic group III mGluRs undergo drastic adaptations to contribute to the enduring remodeling of excitatory synapses and to usually suppress drug seeking behavior. As a result, a loss-of-function mutation (knockout) of individual group III receptor subtypes often promotes drug seeking. This review summarizes the data from recent studies on three group III receptor subtypes (mGluR4/7/8) expressed in the basal ganglia and analyzes their roles in the regulation of dopamine and glutamate signaling in the striatum and their participation in the addictive properties of three major classes of drugs (psychostimulants, alcohol, and opiates). PMID:24078068

  18. CERN Technical Training 2004: New Short Course III (SC III) on Microsoft Outlook - Meetings and Delegation

    CERN Multimedia

    Monique Duval

    2004-01-01

    The CERN Technical Training programme is now proposing a new format for courses on Microsoft Outlook. Three two-hours Short Courses (SC) cover basic and advanced functionalities of the recommended mail client for email at CERN. Each module can be followed independently. The next scheduled session of the 3rd module will take place as follows: Outlook (SC III): Meetings and Delegation. Next session: 9.11.2004 (14:00-16:00) SC III will cover how to organise and manage meetings, work with meeting requests, share tasks, and use email and calendar delegation. The number of participants to each session is limited to 8. The instructor is English-French bilingual, and she will be available some time after each session to answer specific questions, or provide further explanations following demand. The cost of attending any SC module on Outlook is 70.- CHF. The above session will be confirmed if there are enough participants, and the attendance costs will be lower in case of a full class. If you are interested in...

  19. Ion temperatures in TORTUR III

    International Nuclear Information System (INIS)

    Spatially resolved ion-energy distributions are presented for discharges in the TORTUR III tokamak. The measurements are performed in an active method, using a neutral hydrogen probing beam of 20-30 keV, to enhance charge-exchange processes along its path, as well as by the usual passive method. Ion temperatures can amount up to 1 keV

  20. Flora Malesiana, Series III: Bryophyta

    NARCIS (Netherlands)

    Wijk, van der R.

    1951-01-01

    Scope, organization, and purpose of Series III, Flora Malesiana (Musci and Hepaticae) are explained. Collaboration is asked on the following points: (a) To collect Mosses and Hepaticae in Malaysia and to add extensive and detailed data to the specimens (directions available on application to the Edi

  1. C3 functionalization of indolizines via In(iii)-catalyzed three-component reaction.

    Science.gov (United States)

    Jung, Youngeun; Kim, Ikyon

    2015-12-01

    Post-functionalization at the C3 position of indolizines via In(iii)-catalyzed three-component coupling reaction with amines and aldehydes allowed rapid access to a new class of indolizines with diverse functional groups at the C3 position in good to excellent yields. PMID:26380932

  2. Search for the magnetic field of the O7.5 III star ξ Persei

    NARCIS (Netherlands)

    H.F. Henrichs; R.S. Schnerr; J.A. de Jong; L. Kaper; J.F. Donati; C. Catala

    2008-01-01

    Cyclical wind variability is an ubiquitous but as yet unexplained feature among OB stars. The O7.5 III(n)((f)) star ξ Persei is the brightest representative of this class on the Northern hemisphere. As its prominent cyclical wind properties vary on a rotational time scale (2 or 4 days) the star has

  3. Solvent extraction studies of europium(III), ytterbium(III), and lutetium(III) with ionizable macrocyclic ligands and thenoyltrifluoroacetone

    International Nuclear Information System (INIS)

    Solvent extraction behavior of Eu(III), Yb(III), and Lu(III) has been investigated by using thenoyltrifluoroacetone (TTA) as extractant in the presence of 1,7-diaza-4,10,13-trioxacyclopentadecane-N,N'-diacetic acid (DAPDA) and 1,10-diaza-4,7,13,16-tetraoxacyclooctadecane-N,N'-diacetic acid (DACDA) as macrocyclic ionophores. DAPDA and DACDA were chosen in this work in view of their unique complexation toward lanthanides. It was observed that in the presence of DAPDA (L), Eu(III) extracted predominantly as ternary complex [Eu(L)(TTA)], whereas Yb(III) and Lu(III) were extracted as mixed, binary Ln(TTA)3 and ternary [Ln(L)(TTA)] complexes. On the other hand, in the presence of DACDA, Eu(III) formed mixed binary and ternary complexes in the organic phase, whereas Yb(III) and Lu(III) formed predominantly binary complexes. In contrast to the extraction in the presence of DAPDA/DACDA, heavier lanthanides, i.e., Yb(III) and Lu(III), were extracted much less compared to lighter lanthanides, i.e., La(III) and Nd(III), in the presence of ethylenediamine-N,N'-diacetic acid (EDDA), a structurally analogous noncyclic polyaminopolycarboyxlic acid

  4. Experiencing a Flipped Mathematics Class

    OpenAIRE

    Larsen, A. Judy

    2013-01-01

    The flipped classroom is an old concept that has recently been redefined through the emergence of new technologies that allow teachers to deliver content out of class time. As such, various approaches for implementation exist. Most prominently, teachers are able to use class time in a student-centered manner, which allows students to experience the classroom in diverse ways. This study focuses on describing these experiences in a particular flipped adult upgrading mathematics class. Students ...

  5. Class Differences in Cohabitation Processes

    OpenAIRE

    Sassler, Sharon; Miller, Amanda J.

    2011-01-01

    Despite the burgeoning cohabitation literature, research has failed to examine social class variation in processes of forming and advancing such unions. Drawing upon in-depth interviews with 122 working- and middle-class cohabitors, we examine the duration between dating and moving in together, reasons for cohabiting, and subsequent plans. Transitions to cohabitation are more rapid among the working class. Respondents often cohabited for practical reasons—out of financial necessity, because i...

  6. Professional Elites in "Classes" Societies

    OpenAIRE

    2003-01-01

    Modern European identity has been forged in class struggles between the French revolution and fall of the Berlin Wall, which fell twice. Once, with the rest of the city in May 1945, when a national socialist alternative to a modernizing mix of parliamentary democracy and market economy crumbled after the hot WWII, and second time in November 1989, when a state socialist alternative crumbled after the Cold War. At the same time working class in the USA abandoned trade unions and class struggle...

  7. Reconciling Virtual Classes with Genericity

    DEFF Research Database (Denmark)

    Ernst, Erik

    classes. As a result, a kind of type parameters have been introduced, but they are simple and only used where they excel. Conversely, final definitions of virtual classes have been re- moved from the language, thus making virtual classes more flexible. The result- ing language presents a clearer and more...... flexible trade-off between extensibility and predictability, empowering programmers to choose the right balance....

  8. A Molecular Predictor Reassesses Classification of Human Grade II/III Gliomas.

    Directory of Open Access Journals (Sweden)

    Thierry Rème

    Full Text Available Diffuse gliomas are incurable brain tumors divided in 3 WHO grades (II; III; IV based on histological criteria. Grade II/III gliomas are clinically very heterogeneous and their prognosis somewhat unpredictable, preventing definition of appropriate treatment. On a cohort of 65 grade II/III glioma patients, a QPCR-based approach allowed selection of a biologically relevant gene list from which a gene signature significantly correlated to overall survival was extracted. This signature clustered the training cohort into two classes of low and high risk of progression and death, and similarly clustered two external independent test cohorts of 104 and 73 grade II/III patients. A 22-gene class predictor of the training clusters optimally distinguished poor from good prognosis patients (median survival of 13-20 months versus over 6 years in the validation cohorts. This classification was stronger at predicting outcome than the WHO grade II/III classification (P≤2.8E-10 versus 0.018. When compared to other prognosis factors (histological subtype and genetic abnormalities in a multivariate analysis, the 22-gene predictor remained significantly associated with overall survival. Early prediction of high risk patients (3% of WHO grade II, and low risk patients (29% of WHO grade III in clinical routine will allow the development of more appropriate follow-up and treatments.

  9. Separation of scandium(III) and yttrium(III) by tris(2-ethylhexyl)phosphate (TEHP).

    Science.gov (United States)

    Chhatre, M H; Shinde, V M

    1998-10-01

    Tris(2-ethylhexyl)phosphate is proposed as an extractant for scandium(III) and yttrium(III) from salicylate media. The optimum extraction conditions are evaluated and described. The method permits mutual separation of scandium(III) and yttrium(III) and can be used for the separation and determination of scandium(III) and yttrium(III) from binary and multicomponent mixtures. PMID:18967342

  10. First class models from linear and nonlinear second class constraints

    Science.gov (United States)

    Dehghani, Mehdi; Mardaani, Maryam; Monemzadeh, Majid; Nejad, Salman Abarghouei

    2015-10-01

    Two models with linear and nonlinear second class constraints are considered and gauged by embedding in an extended phase space. These models are studied by considering a free non-relativistic particle on the hyperplane and hypersphere in the configuration space. The gauged theory of the first model is obtained by converting the very second class system to the first class one directly. In contrast, the first class system related to the free particle on the hypersphere is derived with the help of the infinite Batalin-Fradkin-Tyutin (BFT) embedding procedure. We propose a practical formula, based on the simplified BFT method, which is practical in gauging linear and some nonlinear second class systems. As a result of gauging these two models, we show that in the conversion of second class constraints to the first class ones, the minimum number of phase space degrees of freedom for both systems is a pair of phase space coordinates. This pair is made up of a coordinate and its conjugate momentum for the first model, but the corresponding Poisson structure of the embedded non-relativistic particle on hypersphere is a nontrivial one. We derive infinite correction terms for the Hamiltonian of the nonlinear constraints and an interacting gauged Hamiltonian is constructed by summing over them. At the end, we find an open algebra for three first class objects of the embedded nonlinear system.

  11. Class Counts: Education, Inequality, and the Shrinking Middle Class

    Science.gov (United States)

    Ornstein, Allan

    2007-01-01

    Class differences and class warfare have existed since the beginning of western civilization, but the gap in income and wealth between the rich (top 10 percent) and the rest has increased steadily in the last twenty-five years. The U.S. is heading for a financial oligarchy much worse than the aristocratic old world that our Founding Fathers feared…

  12. Organic / IV, III-V Semiconductor Hybrid Solar Cells

    Directory of Open Access Journals (Sweden)

    Pang-Leen Ong

    2010-03-01

    Full Text Available We present a review of the emerging class of hybrid solar cells based on organic-semiconductor (Group IV, III-V, nanocomposites, which states separately from dye synthesized, polymer-metal oxides and organic-inorganic (Group II-VI nanocomposite photovoltaics. The structure of such hybrid cell comprises of an organic active material (p-type deposited by coating, printing or spraying technique on the surface of bulk or nanostructured semiconductor (n-type forming a heterojunction between the two materials. Organic components include various photosensitive monomers (e.g., phtalocyanines or porphyrines, conjugated polymers, and carbon nanotubes. Mechanisms of the charge separation at the interface and their transport are discussed. Also, perspectives on the future development of such hybrid cells and comparative analysis with other classes of photovoltaics of third generation are presented.

  13. III-nitride blue microdisplays

    International Nuclear Information System (INIS)

    Prototype blue microdisplays have been fabricated from InGaN/GaN quantum wells. The device has a dimension of 0.5x0.5mm2 and consists of 10x10 pixels 12 μm in diameter. Emission properties such as electroluminescence spectra, output power versus forward current (L--I) characteristic, viewing angle, and uniformity have been measured. Due to the unique properties of III-nitride wide-band-gap semiconductors, microdisplays fabricated from III nitrides can potentially provide unsurpassed performance, including high-brightness/resolution/contrast, high-temperature/high-power operation, high shock resistance, wide viewing angles, full-color spectrum capability, long life, high speed, and low-power consumption, thus providing an enhancement and benefit to the present capabilities of miniature display systems

  14. Solvent extraction of lanthanide ions with 1-phenyl-3-methyl-4-benzoyl-pyrazolone-5 (HPMBP), III: extraction of gadolinium(III), terbium(III), dysprosium(III), holmium(III), and thulium(III) by HPMBP from aqueous solutions

    International Nuclear Information System (INIS)

    The solvent extraction behaviour of Gd(III), Tb(III), Dy(III), Ho(III), and Tm(III) has been investigated using 1-phenyl-3-methyl-4-benzoyl-pyrazolone-5 (HPMBP or HL) in carbon tetrachloride as the extractant. Depending on the concentration of HPMBP in the organic phase the chelates LnL3[Ln(III)=Gd, Tb, Dy, Ho, Tm] and adducts LnL3.HL[Ln(III)=Gd, Tb, Dy, Ho] were extracted. The extraction equilibrium constants (Kex3 or Kex4) for the formation of LnL3 or LnL3.HL and the two-phase stability constants of the chelates or adducts (β3x, β4x) have been evaluated. (authors)

  15. Mechatronic systems and materials III

    CERN Document Server

    Gosiewski, Zdzislaw

    2009-01-01

    This very interesting volume is divided into 24 sections; each of which covers, in detail, one aspect of the subject-matter: I. Industrial robots; II. Microrobotics; III. Mobile robots; IV. Teleoperation, telerobotics, teleoperated semi-autonomous systems; V. Sensors and actuators in mechatronics; VI. Control of mechatronic systems; VII. Analysis of vibration and deformation; VIII. Optimization, optimal design; IX. Integrated diagnostics; X. Failure analysis; XI. Tribology in mechatronic systems; XII. Analysis of signals; XIII. Measurement techniques; XIV. Multifunctional and smart materials;

  16. The Negotiation of Basel III

    DEFF Research Database (Denmark)

    Just, Sine Nørholm

    2015-01-01

    While the Basel Accords of 1988 and 2004 (Basel I and Basel II) ostensibly set out to regulate bank risk at the international level, they were effectively in the grip of neoliberal beliefs in the self-regulating potential of free markets. In 2009–2011, the Basel Accords were revised once more wit...... agency, the empirical argument is substantiated through textual–intertextual analysis of the rhetorical circulation of affective signs in the Basel III negotiations....

  17. Banking Regulatory Standards Basel III

    OpenAIRE

    Costicã Vlad; Maria-Alexandra Spau

    2012-01-01

    Basel Committee issued on December 16, 2010 text Basel III standards framework, which reports on worldwide regulations for capital adequacy and bank liquidity. It is estimated that the rules will help achieve financial stability and promoting economic growth. Combined with a framework of global liquidity, will significantly reduce the likelihood and severity of banking crises in the future by covering the area of micro elements and macroprudentiality. The Framework sets out measures to improv...

  18. French participation to PISC III

    International Nuclear Information System (INIS)

    The PISC III programme was set up in 1986 after the conclusions of the PISC II programme. The main objective was assessment of ISI procedures on few particular components or materials. France with IPSN, CEA/DTA, DCN INDRET, EDF, FRAMATOME and INTERCONTROLE decided to have an important participation in several of the eight actions. This paper describes shortly the key points of this participation and the consequences in France. (authors). 10 figs., 1 tab

  19. The Paradox of Paperless Classes.

    Science.gov (United States)

    Lackie, Paula

    1998-01-01

    Describes paperless classes developed at Carleton College that augment traditional classes by giving students and faculty the ability to share digital course-related materials via the campus computer network. Presents a case study of a managerial economics course, and includes problems with various aspects of the course and solutions. (LRW)

  20. Class, Identity, and Teacher Education

    Science.gov (United States)

    Van Galen, Jane A.

    2010-01-01

    This paper explores the possibilities of working with White, working-class teacher education students to explore the "complex social trajectory" (Reay in Women's Stud Int Forum 20(2):225-233, 1997a, p. 19) of class border crossing as they progress through college. Through analysis of a course that I have developed, "Education and the American…

  1. Social Class and the Extracurriculum

    Science.gov (United States)

    Barratt, Will

    2012-01-01

    Social class is a powerful and often unrecognized influence on student participation in the extracurriculum. Spontaneous student-created extracurricular experiences depend on students affiliating and interacting with each other; student social class is a powerful influence on student affiliations. Students tend to exercise consciousness of kind-…

  2. A Touch of...Class!

    Science.gov (United States)

    Netten, Joan W., Ed.

    1984-01-01

    A collection of ideas for class activities in elementary and secondary language classes includes a vocabulary review exercise and games of memory, counting, vocabulary, flashcard tic-tac-toe, dice, trashcans, questioning, and spelling. Some are designed specifically for French. (MSE)

  3. Class Differences in Cohabitation Processes

    Science.gov (United States)

    Sassler, Sharon; Miller, Amanda J.

    2011-01-01

    Despite the burgeoning cohabitation literature, research has failed to examine social class variation in processes of forming and advancing such unions. Drawing upon in-depth interviews with 122 working- and middle-class cohabitors, we examine the duration between dating and moving in together, reasons for cohabiting, and subsequent plans.…

  4. The Generalizability of Class Means

    Science.gov (United States)

    Kane, Michael T.; Brennan, Robert L.

    1977-01-01

    Dependability of class means is analyzed by applying generalizability to a split-plot design with students nested within classes. Basic generalizability concepts are reviewed, and the derivation and interpretation of distinct generalizability concepts are discussed. Four generalizability coefficients are compared with each other and with the three…

  5. Student Engagement and Marketing Classes

    Science.gov (United States)

    Taylor, Steven A.; Hunter, Gary L.; Melton, Horace; Goodwin, Stephen A.

    2011-01-01

    A study is reported that investigates the goals underlying undergraduate students' engagement in their major classes, nonmajor classes, and in extracurricular activities. The qualitative study employs both focus groups and goal-mapping exercises. The results suggest that students tend to focus on utilitarian, attribute-level considerations mainly…

  6. Predicting Acoustics in Class Rooms

    DEFF Research Database (Denmark)

    Christensen, Claus Lynge; Rindel, Jens Holger

    2005-01-01

    Typical class rooms have fairly simple geometries, even so room acoustics in this type of room is difficult to predict using today's room acoustic computer modeling software. The reasons why acoustics of class rooms are harder to predict than acoustics of complicated concert halls might be...

  7. Dynamic class methods in Java

    OpenAIRE

    Heinlein, Christian

    2005-01-01

    The concept of dynamic class methods in Java, constituting a specialization of a general new programming language concept called dynamic routines, is introduced and applied to a simple case study. Its advantages over standard object-oriented programming techniques including design patterns are demonstrated. Furthermore, an implementation of dynamic class methods as a precompiler-based language extension to Java is described.

  8. Organometallic neptunium(III) complexes

    Science.gov (United States)

    Dutkiewicz, Michał S.; Farnaby, Joy H.; Apostolidis, Christos; Colineau, Eric; Walter, Olaf; Magnani, Nicola; Gardiner, Michael G.; Love, Jason B.; Kaltsoyannis, Nikolas; Caciuffo, Roberto; Arnold, Polly L.

    2016-08-01

    Studies of transuranic organometallic complexes provide a particularly valuable insight into covalent contributions to the metal–ligand bonding, in which the subtle differences between the transuranium actinide ions and their lighter lanthanide counterparts are of fundamental importance for the effective remediation of nuclear waste. Unlike the organometallic chemistry of uranium, which has focused strongly on UIII and has seen some spectacular advances, that of the transuranics is significantly technically more challenging and has remained dormant. In the case of neptunium, it is limited mainly to NpIV. Here we report the synthesis of three new NpIII organometallic compounds and the characterization of their molecular and electronic structures. These studies suggest that NpIII complexes could act as single-molecule magnets, and that the lower oxidation state of NpII is chemically accessible. In comparison with lanthanide analogues, significant d- and f-electron contributions to key NpIII orbitals are observed, which shows that fundamental neptunium organometallic chemistry can provide new insights into the behaviour of f-elements.

  9. Glycosaminoglycans and mucopolysaccharidosis type III.

    Science.gov (United States)

    Jakobkiewicz-Banecka, Joanna; Gabig-Ciminska, Magdalena; Kloska, Anna; Malinowska, Marcelina; Piotrowska, Ewa; Banecka-Majkutewicz, Zyta; Banecki, Bogdan; Wegrzyn, Alicja; Wegrzyn, Grzegorz

    2016-01-01

    Mucopolysaccharidosis type III (MPS III), or Sanfilippo syndrome, is a lysosomal storage disease in which heparan sulfate is accumulated in lysosomes, as well as outside of cells, as the primary storage material. This disease is a complex of four conditions caused by dysfunctions of one of genes coding for lysosomal enzymes involved in degradation of heparan sulfate: SGSH (coding for heparan N-sulfatase) - causing MPS IIIA, NAGLU (coding for alpha-N-acetylglucosaminidase) - causing MPS IIIB, HGSNAT (coding for acetyl CoA alpha-glucosaminide acetyltransferase) - causing MPS IIIC), and GNS (coding for N-acetylglucosamine-6-sulfatase) - causing MPS IIID. The primary storage is responsible for some disease symptoms, but other arise as a result of secondary storage, including glycosphingolipids, and subsequent processes, like oxidative stress and neuroinflammation. Central nervous system is predominantly affected in all subtypes of MPS III. Heparan sulfate and its derivatives are the most commonly used biomarkers for diagnosis and prediction procedures. Currently, there is no therapy for Sanfilippo syndrome, however, clinical trials are ongoing for enzyme replacement therapy, gene therapy and substrate reduction therapy (particularly gene expression-targeted isoflavone therapy). PMID:27100513

  10. Control Class Summaries and Control Class IV from April 1990

    Energy Technology Data Exchange (ETDEWEB)

    Wu, J.; /Fermilab

    1991-02-22

    The D0 cryogenic control system is a complicated system with many facets. Because of the large number and variety of features in the system, a series of ongoing control system training seminars, or control classes, were created in order to keep people up to date on the operation of the system. As of the writing of this engineering note, there have been four classes. The original lecture notes from each class can be found in the cryogenic control room at the D0 Assembly Building, or in the Co-op office. This note provides a summary of the first three control classes, and it includes the entire set of notes from the fourth class, which was held in April of 1990. This class was taught by Jeff Wendlandt and Dan Markley. Dan should be consulted for more complete explanations than those given in the notes. The notes are, in fact, more of a reference for someone who has some experience with the system, than they are a training manual. Most of the pages include pictures and printouts of different menus and functions, useful for finding details without searching through the actual program. In general, this note serves as a pointer to the existence of the control class lecture notes, and as an explanation of their overall contents and purpose.

  11. First class models from linear and nonlinear second class constraints

    CERN Document Server

    Dehghani, Mehdi; Monemzadeh, Majid; Abarghooeinejad, Salman

    2014-01-01

    Two models with linear and nonlinear second class constraints are considered and gauged by embedding in an extended phase space. These models are the free non-relativistic particle on a hyperplane and hyper sphere in configuration space. For the first model we construct its gauged corresponding by the condition of converting second class system to first class one, directly. In contrast the first class system related to the free particle on hyper sphere is derived by the BFT embedding procedure, where its steps are infinite. We give a practical formula for gauging linear and some of the nonlinear second class systems, based on the simplified BFT method. As a result of the gauging two models, we show that in the conversion of second class to the first class constraints the minimum number of phase space degrees of freedom for both systems is a pair of phase space coordinate. This pair for first system is a coordinate and its momentum conjugate, but Poisson structure of embedded non-relativistic particle on hyper...

  12. The temperature influence on sorption of microquantities of cobalt(II), chromium(III) and gallium(III) from aqueous solutions by iron oxide (III)

    International Nuclear Information System (INIS)

    Present article is devoted to temperature influence on sorption of microquantities of cobalt(II), chromium(III) and gallium(III) from aqueous solutions by iron oxide (III). The sorption of cobalt(II), chromium(III) and gallium(III) by iron oxide (III) at a wide temperature ranges and under mononuclear hydrolysis conditions was studied.

  13. Differences in serum concentrations of organochlorine compounds by occupational social class in pancreatic cancer

    International Nuclear Information System (INIS)

    Background: The relationships between social factors and body concentrations of environmental chemical agents are unknown in many human populations. Some chemical compounds may play an etiopathogenic role in pancreatic cancer. Objective: To analyze the relationships between occupational social class and serum concentrations of seven selected organochlorine compounds (OCs) in exocrine pancreatic cancer: dichlorodiphenyltrichloroethane (p,p'-DDT), dichlorodiphenyldichloroethene (p,p'-DDE), 3 polychlorinated biphenyls (PCBs), hexachlorobenzene, and β-hexachlorocyclohexane. Methods: Incident cases of exocrine pancreatic cancer were prospectively identified, and interviewed face-to-face during hospital admission (n=135). Serum concentrations of OCs were analyzed by high-resolution gas chromatography with electron-capture detection. Social class was classified according to occupation. Results: Multivariate-adjusted concentrations of all seven compounds were higher in occupational social classes IV-V (the less affluent) than in classes I-II; they were higher as well in class III than in classes I-II for four compounds. Concentrations of six OCs were higher in manual workers than in non-manual workers (p<0.05 for PCBs). Social class explained statistically between 3.7% and 5.7% of the variability in concentrations of PCBs, and 2% or less variability in the other OCs. Conclusions: Concentrations of most OCs were higher in the less affluent occupational social classes. In pancreatic cancer the putative causal role of these persistent organic pollutants may not be independent of social class. There is a need to integrate evidence on the contribution of different social processes and environmental chemical exposures to the etiology of pancreatic and other cancers

  14. Antithrombin III for critically ill patients

    DEFF Research Database (Denmark)

    Afshari, Arash; Wetterslev, Jørn; Brok, Jesper Sune;

    2008-01-01

    Critical illness is associated with uncontrolled inflammation and vascular damage which can result in multiple organ failure and death. Antithrombin III (AT III) is an anticoagulant with anti-inflammatory properties but the efficacy and any harmful effects of AT III supplementation in critically ...

  15. 21 CFR 1308.13 - Schedule III.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Schedule III. 1308.13 Section 1308.13 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE SCHEDULES OF CONTROLLED SUBSTANCES Schedules § 1308.13 Schedule III. (a) Schedule III shall consist of the drugs and other substances,...

  16. PENGGUNAAN INCLINED BITE PLANE SEBAGAI ALAT BANTU UNTUK KOREKSI GIGITAN SILANG ANTERIOR PADA KASUS MALOKLUSI KLAS III SKELETAL

    Directory of Open Access Journals (Sweden)

    Amutavia P. Artsianti P.

    2015-08-01

    Full Text Available Anterior crossbite occurs in children and adult. This anterior crossbite could be a dental (pseudo class III or a skeletal class III malocclusions. A 15 year old young female came to orthodontic clinic RSGM FKGUI with maxillary dental crowding which canines were more protruded. The dental of mandible were more protruded than maxillary dental. The clinical examination, anamnesis, functional analyses and cephalometric evaluation and model study showed that it was a skeletal class III malocclusion with maxillary skeletal retrusion. To treat the anterior crossbite, the inclined bite plane is used for 2 weeks and followed by fixed appliance. After 2 month treatment, the anterior crossbite is resolved. The result of cephalometric evaluation showed that the use of inclined bite plane as a tool is quite effective to resolve this case.

  17. Separation of gadolinium(III) and lanthanum(III) by nanofiltration-complexation in aqueous medium

    International Nuclear Information System (INIS)

    A new method is proposed for the separation of gadolinium(III) and lanthanum(III) in aqueous medium by nanofiltration combined with a complexation step. First DTPA was chosen as ligand for a selective Gd(III)/La(III) complexation. Having investigated the influence of three factors (pH, temperature and amount of ligand) for the selective complexation of DTPA towards Gd(III) and La(III), the system is then combined with a nanofiltration separation process to remove 92% of initial Gd(III) and only 12% of initial La. (author)

  18. Population III stars around the Milky Way

    OpenAIRE

    Komiya, Yutaka; Suda, Takuma; Fujimoto, Masayuki Y.

    2016-01-01

    We explore the possibility of observing Population III (Pop~III) stars, born of the primordial gas. Pop~III stars with masses below $0.8 M_\\odot$ should survive to date though are not observed yet, but the existence of stars with low metallicity as [Fe/H]$ < -5$ in the Milky Way halo suggests the surface pollution of Pop~III stars with accreted metals from the interstellar gas after birth. In this paper, we investigate the runaway of Pop~III stars from their host mini-halos, considering the e...

  19. Class in Metropolitan India: The Rise of the Middle Classes

    OpenAIRE

    Mooij, Jos; Lama-Rewal, S.T.

    2009-01-01

    textabstractIt is almost a cliché to say that India’s appearance and image (internationally as well as self-image) have changed dramatically in the last fifteen years. Instead of being associated with rural poverty, India is now associated with high rates of economic growth, a booming Information Technology (IT) sector and, particularly, an increasingly expanding middle class that consumes and behaves like elites and middle classes elsewhere in the world. Considering that cities concentrate m...

  20. New Ramsey Classes from Old

    CERN Document Server

    Bodirsky, Manuel

    2012-01-01

    Let C_1 and C_2 be strong amalgamation classes of finite structures, with disjoint finite signatures sigma and tau. Then C_1 wedge C_2 denotes the class of all finite (sigma cup tau)-structures whose sigma-reduct is from C_1 and whose tau-reduct is from C_2. We prove that when C_1 and C_2 are Ramsey, then C_1 wedge C_2 is also Ramsey. We also discuss variations of this statement, and give several examples of new Ramsey classes derived from those general results.

  1. Europium (III) and americium (III) stability constants with humic acid

    International Nuclear Information System (INIS)

    The stability constants for tracer concentrations of Eu(III) and Am(III) complexes with a humic acid extracted from a lake-bottom sediment were measured using a solvent extraction system. The organic extractant was di(2-ethylhexyl)-phosphoric acid in toluene while the humate aqueous phase had a constant ionic strength of 0.1 M (NaClO4). Aqueous humic acid concentrations were monitored by measuring uv-visible absorbances at approx.= 380 nm. The total carboxylate capacity of the humic acid was determined by direct potentiometric titration to be 3.86 +- 0.03 meq/g. The humic acid displayed typical characteristics of a polyelectrolyte - the apparent pKsub(a), as well as the calculated metal ion stability constants increased as the degree of ionization (α) increased. The binding data required a fit of two stability constants, β1 and β2, such that for Eu, log β1 = 8.86 α + 4.39, log β2 = 3.55 α + 11.06 while for Am, log β1 = 10.58 α + 3.84, log β2 = 5.32 α + 10.42. With hydroxide, carbonate, and humate as competing ligands, the humate complex associated with the β1 constant is calculated to be the dominant species for the trivalent actinides and lanthanides under conditions present in natural waters. (orig.)

  2. Mid-Infrared Observations of Class I/Flat-Spectrum Systems in Six Nearby Molecular Clouds

    CERN Document Server

    Haisch, Karl E; Ressler, M E; Greene, T P; Jr., Karl E. Haisch; Barsony, Mary; Ressler, Michael E.; Greene, Thomas P.

    2006-01-01

    We have obtained new mid-infrared observations of 65 Class I/Flat-Spectrum (F.S.) objects in the Perseus, Taurus, Chamaeleon I/II, Rho Ophiuchi, and Serpens dark clouds. We detected 45/48 (94%) of the single sources, 16/16 (100%) of the primary components, and 12/16 (75%) of the secondary/triple components of the binary/multiple objects surveyed. The composite spectral energy distributions (SEDs) for all of our sample sources are either Class I or F.S., and, in 15/16 multiple systems, at least one of the individual components displays a Class I or F.S. spectral index. However, the occurrence of mixed pairings, such as F.S. with Class I, F.S. with Class II, and, in one case, F.S. with Class III, is surprisingly frequent. Such behaviour is not consistent with that of multiple systems among T Tauri stars (TTS), where the companion of a classical TTS also tends to be a classical TTS, although other mixed pairings have been previously observed among Class II objects. Based on an analysis of the spectral indices of...

  3. Characteristic Classes and Weyl Tensor: Applications to General Relativity*

    Science.gov (United States)

    Avez, André

    1970-01-01

    In a recent paper, Chern and Simons proved that the Pontrjagin forms of a Riemannian manifold remain invariant under a conformal deformation. We show that these forms can be expressed uniquely in terms of the conformal curvature tensor: this provides a new proof of their result. Similar techniques can be applied to Euler-Poincare characteristic class, as suggested to me by A. Taub. We obtain the following: If the Weyl tensor of a compact space time is of type III of Bel-Petrov, then it cannot carry a perfect fluid + electromagnetic field. PMID:16591838

  4. Characteristic classes and weyl tensor: applications to general relativity.

    Science.gov (United States)

    Avez, A

    1970-06-01

    In a recent paper, Chern and Simons proved that the Pontrjagin forms of a Riemannian manifold remain invariant under a conformal deformation. We show that these forms can be expressed uniquely in terms of the conformal curvature tensor: this provides a new proof of their result. Similar techniques can be applied to Euler-Poincare characteristic class, as suggested to me by A. Taub. We obtain the following: If the Weyl tensor of a compact space time is of type III of Bel-Petrov, then it cannot carry a perfect fluid + electromagnetic field. PMID:16591838

  5. Extraction of Nd(III), Tb(III) and Lu(III) with picrolonic acid in methylisobutylketone

    International Nuclear Information System (INIS)

    The extraction of Nd(III), Tb(III) and Lu(III) as representatives of lanthanide(III) ions with picrolonic acid (HPA) in methylisobutylketone (MIBK) has been studied from pH 1-2 buffer solutions. The composition of the organic species formed in the organic phase after extraction has been determined by slope analysis to be M(PA)3 [M = Nd(III), Tb(III) and Lu(III)]. The equilibrium constant values, log kex, were deduced to be 2.96±0.02, 2.52±0.05 and 1.52±0.07 for Nd(III), Tb(III) and Lu(III), respectively. The effect of various anions and cations on the extraction of these metal ions has also been studied. Among the masking anions, fluoride, oxalate, citrate and cyanide ions lowered the extraction, whereas presence of Zn(II) Cu(II), Fe(II), Co(II) and Ni(II) has only reduced to 25.87%. The extraction of various other divalent metal ions from pH 2 buffer solution was also studied and high separation factors (103) for the three selected rare earth metal ions were obtained with good selectivity. (author)

  6. III-nitride semiconductor materials

    CERN Document Server

    Feng, Zhe Chuan

    2006-01-01

    III-Nitride semiconductor materials - (Al, In, Ga)N - are excellent wide band gap semiconductors very suitable for modern electronic and optoelectronic applications. Remarkable breakthroughs have been achieved recently, and current knowledge and data published have to be modified and upgraded. This book presents the new developments and achievements in the field. Written by renowned experts, the review chapters in this book cover the most important topics and achievements in recent years, discuss progress made by different groups, and suggest future directions. Each chapter also describes the

  7. Macroeconomic Impact of Basel III

    OpenAIRE

    Patrick Slovik; Boris Cournède

    2011-01-01

    The estimated medium-term impact of Basel III implementation on GDP growth is in the range of -0.05 to -0.15 percentage point per annum. Economic output is mainly affected by an increase in bank lending spreads as banks pass a rise in bank funding costs, due to higher capital requirements, to their customers. To meet the capital requirements effective in 2015 (4.5% for the common equity ratio, 6% for the Tier 1 capital ratio), banks are estimated to increase their lending spreads on average b...

  8. Recent results for Mark III

    Energy Technology Data Exchange (ETDEWEB)

    Brient, J.C.

    1987-12-01

    This paper presents recent results from the Mark III detector at SPEAR, in the open charm sector. The first topic discussed is the reanalysis of the direct measurement of the D hadronic branching fractions, where a detailed study has been made of the Cabibbo suppressed and multi-..pi../sup 0/'s D decays backgrounds in the double tag sample. Next, the Dalitz plot analysis of the D decays to K..pi pi.. is presented, leading to the relative fractions of three-body versus pseudoscalarvector decays. 7 refs., 5 figs.

  9. Recent results for Mark III

    International Nuclear Information System (INIS)

    This paper presents recent results from the Mark III detector at SPEAR, in the open charm sector. The first topic discussed is the reanalysis of the direct measurement of the D hadronic branching fractions, where a detailed study has been made of the Cabibbo suppressed and multi-π0's D decays backgrounds in the double tag sample. Next, the Dalitz plot analysis of the D decays to Kππ is presented, leading to the relative fractions of three-body versus pseudoscalarvector decays. 7 refs., 5 figs

  10. Comprehensive evaluation of functional and anatomical disorders of the patients with distal occlusion and accompanying obstructive sleep apnea syndrome

    Science.gov (United States)

    Nabiev, F. H.; Dobrodeev, A. S.; Libin, P. V.; Kotov, I. I.; Ovsyannikov, A. G.

    2015-11-01

    The paper defines the therapeutic and rehabilitation approach to the patients with Angle's classification Class II dento-facial anomalies, accompanied by obstructive sleep apnea (OSA). The proposed comprehensive approach to the diagnostics and treatment of patients with posterior occlusion, accompanied by OSA, allows for objective evaluation of intensity of a dento-facial anomaly and accompanying respiratory disorders in the nasal and oral pharynx, which allows for the pathophysiological mechanisms of OSA to be identified, and an optimal plan for surgical procedures to be developed. The proposed comprehensive approach to the diagnostics and treatment of patients with Angle's classification Class II dento-facial anomalies provides high functional and aesthetic results.

  11. Second class currents and nuclei

    International Nuclear Information System (INIS)

    A theoretical analysis of the recent experimental data relevant to second-class currents is made on the basis of the effective two-body operator approach proposed several years ago by the present authors. It takes into account nuclear many-body effects such as off-the-energy-shell and meson-exchange effects. The previous results indicating the presence of second-class currents comparable in their magnitudes to the weak magnetism term are altered. Next, we suggest that mesonic effects on the time-component of first-class axial current can be tested unambiguously. The argument is based on the low-energy theorem and model-independent to great degree. We emphasize that further correlation experiments are highly desirable not only for testing the second-class currents but also making a clean test of the mesonic effects on axial current. (author)

  12. Integrals of the Ising Class

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, Jonathan M.; Crandall, Richard E.

    2006-06-01

    From an experimental-mathematical perspective we analyze"Ising-class" integrals. Our experimental results involvedextreme-precision, multidimensional quadrature on intricate integrands;thus, highly parallel computation was required.

  13. Class attendance and university performance

    OpenAIRE

    Hoffmann, Anna-Lena; Lerche, Katharina

    2016-01-01

    Using survey data collected at Göttingen University, Germany, this paper evaluates the effect of attending the lecture and/or tutorial on the grade achieved in two basic courses in business administration and economics. The analysis shows that going to class has no significant impact on student performance in most specifications. Although the identification of a causal effect may not be possible with the data at hand, the results suggest that, in the given framework, attending class and study...

  14. Whole Class Laboratories: More Examples

    Science.gov (United States)

    Kouh, Minjoon

    2016-03-01

    Typically, introductory physics courses are taught with a combination of lectures and laboratories in which students have opportunities to discover the natural laws through hands-on activities in small groups. This article reports the use of Google Drive, a free online document-sharing tool, in physics laboratories for pooling experimental data from the whole class. This pedagogical method was reported earlier, and the present article offers a few more examples of such "whole class" laboratories.

  15. Internet service classes under competition

    OpenAIRE

    Gibbens, R.; R. Mason; Steinberg, Richard

    2000-01-01

    This paper analyzes competition between two Internet service providers (ISPs), either or both of which may choose to offer multiple service classes. In the model analyzed, a social planner who maximizes the total benefit from network usage and a profit maximizing monopolist will both form multiple service classes; but two networks competing to maximize profits will not. The reason is that a competition effect always outweighs a segmentation effect. Networks wish to offer multiple service clas...

  16. Less than a Class Set

    Science.gov (United States)

    Bennett, Kristin Redington

    2012-01-01

    The iPad holds amazing potential for classroom use. Just a few--or even only one--is enough to get results. Having a class set promotes traditional, whole-class instruction, but fewer iPads facilitate individualized and tailored instruction. In this article, the author discusses the potential of the iPad and suggests ways to put the iPad to use in…

  17. Alternative treatment for open bite Class III malocclusion in a child with Williams-Beuren syndrome

    Directory of Open Access Journals (Sweden)

    Giovanni Modesto Vieira

    2015-02-01

    Full Text Available Williams-Beuren syndrome (WBS is a rare genetic condition that affects approximately 1 in every 20,000 - 50,000 live births. WBS children have specific skeletal deformities, dental malformations and rare lingual muscle dysfunction. The need for orthodontic and orthognathic therapy has arisen and has been considered a real clinical challenge even for experienced professionals, once it requires a complex and individualized treatment plan. This study reports a case of orthopedic expansion of the maxilla, in which a modified facial mask was used for protraction of the maxillary complex associated with clockwise rotation of the maxilla. In addition, special considerations about treatment time and orthopedic outcomes are discussed.

  18. Evaluation of a class III biological safety cabinet for enclosure of an ultracentrifuge.

    Science.gov (United States)

    Chatigny, M A; Dunn, S; Ishimaru, K; Eagleson, J A; Prusiner, S B

    1979-11-01

    An evaluation of a special safety cabinet housing a high-speed centrifuge was made. The cabinet enclosed both the top access port and the drive and pumping machinery of the centrifuge. A titanium rotor was loaded with tubes containing a bacterial culture, weakened, and driven until rotor rupture occurred. There were several bent and broken components in the centrifuge, and bacteria leaked from the vacuum chamber. Although the forces were sufficient to displace the cabinet, none of the test bacteria were found outside the cabinet. PMID:543704

  19. 78 FR 20268 - Effective Date of Requirement for Premarket Approval for Three Class III Preamendments Devices...

    Science.gov (United States)

    2013-04-04

    ... may lead to electrical shocks in patients using them. Electromagnetic interference, which may lead to...; ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration 21 CFR Parts 876, 882, and 892 Effective... intended for human use. Section 513 of the FD&C Act (21 U.S.C. 360c) established three categories...

  20. Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. class III beta-tubulin

    Czech Academy of Sciences Publication Activity Database

    Katsetos, C.D.; Dráberová, Eduarda; Legido, A.; Dumontet, C.; Dráber, Pavel

    2009-01-01

    Roč. 221, č. 3 (2009), s. 505-513. ISSN 0021-9541 R&D Projects: GA AV ČR KAN200520701 Institutional research plan: CEZ:AV0Z50520514 Keywords : Beta-II-tubulin * glioblastoma Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.586, year: 2009

  1. [Thiotriazoline in the Treatment of Stable Angina Pectoris of II-III Functional Class].

    Science.gov (United States)

    Kadin, D V; Chumak, B A; Filippov, A E; Shustov, S B

    2015-01-01

    Trimetazidine is a metabolic agent of proven efficacy in improving myocardial ischemia and angina. A comparative international multicenter randomized trial, assessed anti-anginal anti ischemic efficacy and safety of Trimetazidine (60 mg/d) and Thiotriazoline (600 mg/d) in symptomatic patients with chronic ischemic heart disease receiving the first line therapy. The study assessed the efficacy of the two drugs on total exercise duration, time to 1-mm ST segment depression, the number of angina attacks and nitroglycerin tablets consumed amount. Both drugs have demonstrated clinical efficacy equal for all primary and secondary endpoints. PMID:26761968

  2. 78 FR 4094 - Effective Date of Requirement for Premarket Approval for Two Class III Preamendments Devices

    Science.gov (United States)

    2013-01-18

    ... references the aforementioned Australian registry. A recent article published in a scientific journal raised... recent article published in a scientific journal raised serious concerns about the failure rates of metal... 90 days of the publication of the final order. See section X of this document for the...

  3. Dofetilide: a class III anti-arrhythmic drug for the treatment of atrial fibrillation

    DEFF Research Database (Denmark)

    Torp-Pedersen, C; Brendorp, B; Køber, L

    2000-01-01

    dofetilide. After pharmacological or electrical conversion of atrial fibrillation to sinus rhythm in these studies, the probability of remaining in sinus rhythm during the following year was 75%. Dofetilide has a single significant side effect: risk of developing torsade de pointes ventricular tachycardia...... infarctions, only amiodarone and dofetilide have proven safety and dofetilide is a strong candidate for first choice treatment when the aim is to achieve sinus rhythm....

  4. The Return of Two-Class Medicine—III Effects of Medi-Cal Reform

    OpenAIRE

    Waitzkin, Howard

    1985-01-01

    California's drastic Medi-Cal reforms have created great difficulties in health care for the poor. Patients' clinical problems seldom are apparent in descriptions of changes in public insurance programs. Rapidly escalating costs of Medi-Cal led to irresistible pressures for reform, especially from the business community. The new Medi-Cal regulations provide for prospective contracts with hospitals for inpatient services, the transfer of “Medically Indigent Adults” to the responsibility of cou...

  5. PSA NCAM and class III beta-tubulin expression in the developing inner ear in mice

    Czech Academy of Sciences Publication Activity Database

    Buckiová, Daniela; Syka, Josef

    Geneva : Federation of European Neurosciences Societies, 2008. s. 179.1. [FENS. Forum of European Neuroscience /6./. 12.07.2008-16.07.2008, Geneva] R&D Projects: GA MŠk(CZ) LC554; GA ČR GA309/04/1074 Institutional research plan: CEZ:AV0Z50390512 Keywords : Development * Sensory * Other sensory systems Subject RIV: FH - Neurology

  6. Differential expression of gamma-tubulin and class III beta-tubulin in meduloblastoma cell lines

    Czech Academy of Sciences Publication Activity Database

    Caracciolo, V.; D´Agostino, L.; Dráberová, Eduarda; Sládková, Vladimíra; Agamanolis, D.; De Chaderevian, J.P.; Legido, A.; Giordano, A.; Dráber, Pavel; Katsetos, C.

    2010-01-01

    Roč. 69, č. 5 (2010), s. 558-558. ISSN 0022-3069. [Annual Meeting of the American-Association-of-Neuropathologists /86./. 10.06.10-13.06.10, Phidadelphia] Institutional research plan: CEZ:AV0Z50520514

  7. A class of discontinuous Petrov–Galerkin methods. Part III: Adaptivity

    KAUST Repository

    Demkowicz, Leszek

    2012-04-01

    We continue our theoretical and numerical study on the Discontinuous Petrov-Galerkin method with optimal test functions in context of 1D and 2D convection-dominated diffusion problems and hp-adaptivity. With a proper choice of the norm for the test space, we prove robustness (uniform stability with respect to the diffusion parameter) and mesh-independence of the energy norm of the FE error for the 1D problem. With hp-adaptivity and a proper scaling of the norms for the test functions, we establish new limits for solving convection-dominated diffusion problems numerically: ε=10 -11 for 1D and ε=10 -7 for 2D problems. The adaptive process is fully automatic and starts with a mesh consisting of few elements only. © 2011 IMACS. Published by Elsevier B.V. All rights reserved.

  8. Bone graft on the labial symphysis for the skeletal Class III case

    OpenAIRE

    石亀, 勝; 清野, 幸男; 横田,光正; 水城, 春美; 三浦, 廣行; イシガメ, マサル; セイノ, ユキオ; ヨコタ, ミツマサ; ミズキ, ハルミ; ミウラ, ヒロユキ; Masaru, ISHIGAME; Yukio, SEINO; Mitsumasa, YOKOTA; Harumi, MIZUKI; Hiroyuki, Miura

    2003-01-01

    通常臨床歯科医学における骨移植は,その病理学的形態より3壁性骨欠損を有する歯周病患者に対して広く行われている。今回,下顎前歯部(下顎結合部)唇側面歯槽骨の開窓や限局性穿孔は存在するが,歯肉退縮を生じていない骨格型III級不正咬合患者へ顎矯正手術と同時に自家骨移植を付加的に行った。初診時のセファログラム所見より高く幅の狭い下顎結合部とこの薄い骨に直立している下顎前歯が確認された。また,術前矯正歯科治療中,下顎前歯はその捻転の解消と頬舌的な移動が行われた。手術時には下顎前歯部の開窓や限局性穿孔が確認された。下顎前歯部(下顎結合部)唇側面に自己海面骨を移植することによって歯槽骨の開窓や限局性穿孔は覆われた。結果的にセファログラム上での経過所見より,その後4年10か月間移植骨の残留が認められ,さらに臨床的に咬合が安定し通常後戻りしやすいとされる下顎前歯捻転の後戻りも認められず良好な結果を得たので報告した。...

  9. Shoot Meristem Function and Leaf Polarity: The Role of Class III HD–ZIP Genes

    OpenAIRE

    Byrne, Mary E

    2006-01-01

    The shoot apical meristem comprises an organized cluster of cells with a central region population of self-maintaining stem cells providing peripheral region cells that are recruited to form differentiated lateral organs. Leaves, the principal lateral organ of the shoot, develop as polar structures typically with distinct dorsoventrality. Interdependent interactions between the meristem and developing leaf provide essential cues that serve both to maintain the meristem and to pattern dorsoven...

  10. Correction of transverse maxillary deficiency and anterior open bite in an adult Class III skeletal patient

    OpenAIRE

    Prerna Hoogan Teja; Samarjit Singh Teja; Nayak, Rabindra S; Abhijit Bagade; Manu Rashmi Sharma

    2016-01-01

    Transverse maxillary deficiency may be associated with sagittal or vertical problems of the maxilla or mandible. It may contribute to unilateral or bilateral posterior crossbite, anterior dental crowding, and unesthetic black buccal corridors on smiling. An adequate transverse dimension is important for stable and proper functional occlusion. Surgically, assisted rapid palatal expansion has been the treatment of choice to resolve posterior crossbite in skeletally mature patients. The followin...

  11. Antibody formation against beta-tubulin class III in response to brain trauma

    Czech Academy of Sciences Publication Activity Database

    Škoda, D.; Kranda, K.; Bojar, M.; Glosová, L.; Bäurle, J.; Kenney, Jana; Romportl, D.; Pelichovská, M.; Cvachovec, K.

    2006-01-01

    Roč. 68, č. 4 (2006), s. 213-216. ISSN 0361-9230 R&D Projects: GA MZd(CZ) NR8114 Institutional research plan: CEZ:AV0Z5011922 Keywords : autoantibodies * beta–tubulin * brain injury Subject RIV: FH - Neurology Impact factor: 1.684, year: 2006

  12. Rare Mycetes of Romania III

    Directory of Open Access Journals (Sweden)

    Denes PAZMANY

    1981-08-01

    Full Text Available New contributions to the knowledges concerning Romania's macromycetes are presented. The 208 species enlisted in the paper are grouped in classes and orders and within these groups the species are enlisted alphabetically. The data refers to species less known to Romania, collected in Transylvania, mostly around Cluj-Napoca. From these Daldinia vernicosa, Pleurotus calyptratus, Agaricus pseudopratensis, Armillariella bulbosa, Clitocybe harmajae and Tubaria hiemalis are rare in all Europe.

  13. Transformational III-V Electronics

    KAUST Repository

    Nour, Maha A.

    2014-04-01

    Flexible electronics using III-V materials for nano-electronics with high electron mobility and optoelectronics with direct band gap are attractive for many applications. This thesis describes a complementary metal oxide semiconductor (CMOS) compatible process for transforming traditional III-V materials based electronics into flexible one. The thesis reports releasing 200 nm of Gallium Arsenide (GaAs) from 200 nm GaAs / 300 nm Aluminum Arsenide (AlAs) stack on GaAs substrate using diluted hydrofluoric acid (HF). This process enables releasing a single top layer compared to peeling off all layers with small sizes at the same time. This is done utilizing a network of release holes that contributes to the better transparency (45 % at 724 nm wavelengths) observed. Fabrication of metal oxide semiconductor capacitor (MOSCAPs) on GaAs is followed by releasing it to have devices on flexible 200 nm GaAs. Similarly, flexible GaSb and InP fabrication process is also reported to transform traditional electronics into large-area flexible electronics.

  14. A New Complete Class Complexity Metric

    OpenAIRE

    Singh, Vinay; Bhattacherjee, Vandana

    2014-01-01

    Software complexity metrics is essential for minimizing the cost of software maintenance. Package level and System level complexity cannot be measured without class level complexity. This research addresses the class complexity metrics. This paper studies the existing class complexity metrics and proposes a new class complexity metric CCC (Complete class complexity metric). The CCC metric is then analytically evaluated by Weyuker's property.

  15. Determination of midsagittal plane for evaluation of facial asymmetry using three-dimensional computed tomography

    International Nuclear Information System (INIS)

    The aim of the present study was to investigate the disagreement of cephalometric analysis depending on the reference determination of midsagittal plane on three-dimensional computed tomography. A total of 102 young women with class III dentofacial deformity were evaluated using three-dimensional computed tomography. The cranial and facial midsagittal planes were defined and the amounts of jaw deviation were calculated. The amounts of jaw deviation were compared with paired t-test (2-tailed) and Bland-Altman plot was drawn. The landmark tracing were reproducible (r≥.978). The jaws relative to the cranial midsagittal plane were 10-17 times more significantly deviated than to the facial midsagittal plane (P<.001). Bland-Altman plot demonstrated that the differences between the amounts of jaw deviation from two midsagittal planes were not normally distributed versus the average of the amounts of jaw deviation from two midsagittal planes. The cephalometric analyses of facial asymmetry were significantly inconsistent depending on the reference determination of midsagittal plane. The reference for midsagittal plane should be carefully determined in three-dimensional cephalometric analysis of facial asymmetry of patients with class III dentofacial deformity.

  16. Classes subalternas, lutas de classe e hegemonia: uma abordagem gramsciana Subaltern classes, class struggles and hegemony: a gramscian approach

    Directory of Open Access Journals (Sweden)

    Ivete Simionatto

    2009-06-01

    Full Text Available O artigo procura resgatar, no pensamento de Antonio Gramsci, a concepção de classes subalternas e a sua relação com outras categorias, especialmente, o Estado, a sociedade civil e a hegemonia, como suportes da luta de classes na realidade contemporânea. Aborda, ainda, as relações entre classes subalternas, senso comum e ideologia, bem como as formas de superação tematizadas por Gramsci, através da cultura e da filosofia da práxis. Nesse sentido, num movimento de totalidade, busca recuperar a discussão das classes subalternas, a partir da original formulação gramsciana no âmbito do marxismo, mediante a interação dialética entre estrutura e superestrutura, economia e política. Além do resgate conceitual, apontam-se alguns elementos como subsídios à discussão das formas de subalternidade presentes na realidade contemporânea e as possibilidades de fortalecimento das lutas de tais camadas de classe, sobretudo em momentos de forte desmobilização da participação popular.This article sought to revive the concept of subaltern classes and their relation with other categories, particularly the State, civil society and hegemony in the thinking of Antonio Gramsci, as a support for contemporary class struggles. It also analyzes the relations between subaltern classes, common sense and ideology, as well as the forms of "overcoming" conceptualized by Gramsci, through the culture and philosophy of praxis. The paper revives the discussion of the subaltern classes, based on the original Gramscian formulation in the realm of Marxism, through the dialectic interaction between structure and superstructure, economy and politics. In addition to the conceptual revival, it indicates some elements that can support the discussion of the forms of subalternity found in contemporary reality and the possibilities for strengthening the struggles of these class layers, above all in moments of strong demobilization of popular participation.

  17. Seismic considerations for ASME class 1 piping systems

    International Nuclear Information System (INIS)

    ASME Boiler and Pressure Vessel Code Section III requires that Class 1 piping systems be designed and analyzed to account for self-limiting and non-self-limiting loads for primary stress and fatigue protection. The NRC requires demonstration of equipment operability and piping system functional capability in addition to the structural integrity requirements for Class 1 systems. The NSSS vendors impose further restrictions on these systems in order to satisfy systems design criteria to comply with the assumed loadings utilized in their safeguard analyses. All these requirements, as well as any additional plant specific criteria, restrict and control the design of the Class 1 piping systems. A procedure is required to optimize the design and analysis of these systems, which, in most cases, are governed by systems operating transients and seismic loadings. The objective of this paper is to present a technical overview of seismic analysis of Class 1 piping systems in the areas of: methods of analysis, linearization of non-linear systems, response spectral considerations, coupling and resonance between systems, equipment modeling and limitations, support consideration and optimization, generic fatigue analysis concept, special techniques to resolve overstress problems and criteria to assess as-built deviations

  18. Design of Class-E Radio Frequency Power Amplifier

    OpenAIRE

    Al-Shahrani, Saad Mohammed

    2000-01-01

    Power amplifiers (PA) are typically the most power-consuming building blocks of RF transceivers. Therefore, the design of a high-efficiency radio frequency power amplifier is the most obvious solution to overcoming the battery lifetime limitation in the portable communication systems. A power amplifierà ­s classes (A, AB, B, C, F, E, etc), and design techniques (Load-pull and large-signal S-parameters techniques) are presented. The design accuracy of class-A power amplifier based on the s...

  19. High Power Wideband Class-E Power Amplifier

    OpenAIRE

    Ortega González, Francisco Javier

    2010-01-01

    This letter shows a high-power, high-efficiency, wideband Class-E RF power amplifier designed upon the load admittance synthesis concept and built using an uncomplicated low-loss load network with a low loss wideband admittance transformer as the main component. It uses a power Silicon LDMOS transistor to provide up to 145 W at 28 V peak power, up to 86% drain efficiency over 35% fractional bandwidth (from 85 to 120 MHz) and 15.6 dB gain at peak power without any adjustments. These are clear ...

  20. Nitrato-complexes of Y(III), La(III), Ce(III), Pr(III), Nd(III), Sm(III), Gd(III), Tb(III), Dy(III) and Ho(III) with 2-(2'-pyridyl) benzimidazole

    International Nuclear Information System (INIS)

    The nitrato-complexes, [Y(PyBzH)2(NO3)2]NO3.H2O and Nd, Sm, Gd, Tb, Dy, Ho ; n=1-3, m=0-0.5 ; PyBzh=2-(2 -pyridyl)benzimidazole] are formed on interaction of the ligand with metal nitrates in ethanol. The electrical conductance values (116-129 ohm-1cm2mol-1) suggest 1:1 electrolyte-nature of the complexes. Magnetic moment values of Ce(2.53 B.M.), Pr(3.62 B.M.), Nd(3.52 B.M.), Sm(1.70 B.M.), Gd(8.06 B.M.), Tb(9.44 B.M.), Dy(10.56 B.M.) and Ho(10.51 B.M.) in the complexes confirm the terpositive state of the metals. Infrared evidences are obtained for the existance of both coordinated (C2v) and uncoordinated (D3h) nitrate groups. Electronic absorption spectra of Pr(III)-, Nd(III)-, Sm(III)-, Tb(III)-, Dy(III)- and Ho(III)-complexes have been analysed in the light of LSJ terms. (author)

  1. The SINTRAN III NODAL system

    International Nuclear Information System (INIS)

    NODAL is a high level programming language based on FOCAL and SNOBOL4, with some influence from BASIC. The language was developed to operate on the computer network controlling the SPS accelerator at CERN. NODAL is an interpretive language designed for interactive use. This is the most important aspect of the language, and is reflected in its structure. The interactive facilities make it possible to write, debug and modify programs much faster than with compiler based languages like FORTRAN and ALGOL. Apart from a few minor modifications, the basic part of the Oslo University NODAL system does not differ from the CERN version. However, the Oslo University implementation has been expanded with new functions which enable the user to execute many of the SINTRAN III monitor calls from the NODAL level. In particular the most important RT monitor calls have been implemented in this way, a property which renders possible the use of NODAL as a RT program administrator. (JIW)

  2. Solvent extraction of scandium(III)

    International Nuclear Information System (INIS)

    Separation of scandium(III) from iron(III), molybdenum(VI), vanadium(V), chromium(VI), titanium(IV), bismuth(III), zirconium(IV), lanthanum(III), and thorium(IV) is achieved by solvent extraction with mesityl oxide from sodium sallcylate solution (0.1 M) adjusted to pH 4. Scandium from the organic phase is stripped with water and determined photometrically as its arsenazo complex at 570 nm. The extracted species is trisolvated, i.e., Sc(HOC6H4COO)33Me0. 1 figure, 1 table

  3. Characterization of ribonuclease III from Brucella.

    Science.gov (United States)

    Wu, Chang-Xian; Xu, Xian-Jin; Zheng, Ke; Liu, Fang; Yang, Xu-Dong; Chen, Chuang-Fu; Chen, Huan-Chun; Liu, Zheng-Fei

    2016-04-01

    Bacterial ribonuclease III (RNase III) is a highly conserved endonuclease, which plays pivotal roles in RNA maturation and decay pathways by cleaving double-stranded structure of RNAs. Here we cloned rncS gene from the genomic DNA of Brucella melitensis, and analyzed the cleavage properties of RNase III from Brucella. We identified Brucella-encoding small RNA (sRNA) by high-throughput sequencing and northern blot, and found that sRNA of Brucella and Homo miRNA precursor (pre-miRNA) can be bound and cleaved by B.melitensis ribonuclease III (Bm-RNase III). Cleavage activity of Bm-RNase III is bivalent metal cations- and alkaline buffer-dependent. We constructed several point mutations in Bm-RNase III, whose cleavage activity indicated that the 133th Glutamic acid residue was required for catalytic activity. Western blot revealed that Bm-RNase III was differently expressed in Brucella virulence strain 027 and vaccine strain M5-90. Collectively, our data suggest that Brucella RNase III can efficiently bind and cleave stem-loop structure of small RNA, and might participate in regulation of virulence in Brucella. PMID:26778206

  4. Towards a Class Struggle Anthropology

    Directory of Open Access Journals (Sweden)

    Charles R. Menzies

    2007-05-01

    Full Text Available Dancing between review and argument this paper lays out a foundation for a class-struggle anthropology -that is, an anthropological practice that can be linked to the ultimate goal of achieving a classless society. To this end we will review those anthropologists who have gone before us, pulling out those works of theirs that we see as critical in (rebuilding a class-struggle anthropology. As part of this process we discuss the relationship between what has stood as Marxist anthropology in North America, the idea of socialism, the political development of the world working class during nine decades since the October Revolution, and the challenges of intellectual continuity in the face of differing generational experiences of Marxist anthropologists. Ultimately we argue that a progressive anthropology necessarily involves political activism in our work, communities, and schools.

  5. Theoretical Prediction of Topological Insulators in Thallium-based III-V-VI$_2$ Ternary Chalcogenides

    OpenAIRE

    Yan, Binghai; Liu, Chao-Xing; Zhang, Hai-Jun; Yam, Chi-Yung; Qi, Xiao-Liang; Frauenheim, Thomas; Zhang, Shou-Cheng

    2010-01-01

    We predict a new class of three dimensional topological insulators in thallium-based III-V-VI$_2$ ternary chalcogenides, including TlBiQ$_2$ and TlSbQ$_2$ (Q = Te, Se and S). These topological insulators have robust and simple surface states consisting of a single Dirac cone at the $\\Gamma$ point. The mechanism for topological insulating behavior is elucidated using both first principle calculations and effective field theory models. Remarkably, one topological insulator in this class, TlBiTe...

  6. A library of function classes

    International Nuclear Information System (INIS)

    We have written a library of function classes in C++, which is distributed as part of the CLHEP foundation class libraries for High Energy Physics. The main goals of the library are to provide objects having all the mathematical behavior of functions, and to provide a mechanism for parameterizing these functions. Our functions support all the normal function operations such as addition, subtraction, multiplication, division, composition, et. cetera. The library allows programmers to compose complicated one-or multi-dimensional functions with great economy and natural semantics

  7. Professional Elites in "Classes" Societies

    OpenAIRE

    Magala, Slawomir

    2003-01-01

    textabstractModern European identity has been forged in class struggles between the French revolution and fall of the Berlin Wall, which fell twice. Once, with the rest of the city in May 1945, when a national socialist alternative to a modernizing mix of parliamentary democracy and market economy crumbled after the hot WWII, and second time in November 1989, when a state socialist alternative crumbled after the Cold War. At the same time working class in the USA abandoned trade unions and cl...

  8. On uniqueness of characteristic classes

    DEFF Research Database (Denmark)

    Feliu, Elisenda

    2011-01-01

    We give an axiomatic characterization of maps from algebraic K-theory. The results apply to a large class of maps from algebraic K-theory to any suitable cohomology theory or to algebraic K-theory. In particular, we obtain comparison theorems for the Chern character and Chern classes and for the...... Adams operations and ¿-operations on higher algebraic K-theory. We show that the Adams operations and ¿-operations defined by Grayson agree with the ones defined by Gillet and Soulé....

  9. Separation of americium(III) from lanthanides(III) by nanofiltration-complexation in aqueous medium

    International Nuclear Information System (INIS)

    The separation of Am(III) from a mixture of lanthanides(III) was performed in aqueous medium by nanofiltration combined with a complexation step using a DTPA derivative as selective complexing agent. (author)

  10. PENGGUNAAN FACE-MASK & EKSPANSI PALATAL PADA PERAWATAN MALOKLUSI KLAS III (Studi Pustaka

    Directory of Open Access Journals (Sweden)

    Krisnawati Krisnawati

    2015-08-01

    Full Text Available Class III skeletal anomaly is one of the most difficult malocclusions to correct in orthodontics. Orthodontist usually involved chincup appliances to restrain mandibular growth, camouflage techniques to advances maxillary incisors and retract mandibular incisors or waiting untul growth ceased to pursue orthognathic surgery. Many studies found that most of Class III malocclusions were characterized by maxillary retrognathism. In the late 1960s, the Delaire mask was popularized to protract the maxilla. The development of maxillary protraction with facemask and palatal expansion have provided a predictable and effective approach to managing treatment that was once considered difficult. Although no significant difference was found between early or late treatment group, the effect of improvement in facial aesthetics on psychosocial development resulted in a significant advantage for early treatment. However, the effects of face mask therapy should be evaluated over the long term in order to determine the relaps tendency.

  11. Clinical Importance of The Lens Opacities Classification System III (LOCS III) in Phacoemulsification

    OpenAIRE

    Benčić, Goran; Zorić-Geber, Mia; Šarić, Dean; Čorak, Maja; Mandić, Zdravko

    2005-01-01

    The aim of this study was to compare the correlation of features of cataracts graded by the Lens Opacities Classification System, version III (LOCS III) with recorded operative characteristics during the phacoemulsification. The retrospective study included 245 cases operated on by a single surgeron from October 2003 to March 2004. The cataract was graded at the biomicroscope using the 4 grading scales of the lens opacities classification sistem, version III (LOCS III); nuclear op...

  12. Evaluation of the dental arch asymmetry in natural normal occlusion and Class II malocclusion individuals

    Directory of Open Access Journals (Sweden)

    Paulo Estevão Scanavini

    2012-02-01

    Full Text Available OBJECTIVE: To verify the presence and degree of asymmetry of dental arches in Brazilian individuals with natural normal occlusion and Class II, Divisions 1 and 2 malocclusions. METHODS: The study evaluated the symmetry of the maxillary and mandibular dental arches of 180 pairs of dental casts, divided into: Group I = 60 pairs of natural normal occlusion individuals; Group II = 60 pairs of Class II, Division 1 malocclusion individuals; and Group III = 60 pairs of Class II, Division 2 malocclusion individuals. A device was used to measure dental midline deviation and the canine tip in the dental arches (in degrees. It was also verified the distance of the upper canines from the palatal suture, intercanine distance, and anteroposterior upper and lower first molar position. RESULTS: Dental arches of individuals from all groups presented asymmetry, regardless of the presence of malocclusion. Group I showed a lower asymmetry degree in relation to Groups II and III. The asymmetry in Groups II and III was similar. CONCLUSION: The dental arches of individuals with natural normal occlusion and with Class II, Division 1 and Division 2 malocclusions showed asymmetry. The asymmetry degree was higher in the mandibular dental arches than in the maxillary dental arches in all 3 evaluated groups.

  13. A note on classification of proper homothetic vector fields in Kantowski-Sachs and Bianchi type III Lorentzian manifolds

    CERN Document Server

    Shabbir, Ghulam

    2011-01-01

    A complete study of Kantowski-Sachs and Bianchi type III space-times according to their proper homothetic vector fields is given by using direct integration technique. Using the above mentioned technique we have shown that very special classes of the above space-times admit proper homothetic vector fields. The dimension of homothetic vector fields is five.

  14. Achieving world class maintenance status

    Energy Technology Data Exchange (ETDEWEB)

    Tomlingson, P.D. [Paul D. Tomingson Associates (United States)

    2007-08-15

    The article written by a management consultant, discusses the art of successful planning and operation of maintenance in mines considering factors such as benchmaking, key performance indices (KPIs) and frequency of procedures which can help achieve 'world class maintenance'. 1 fig.

  15. Social Class and School Music

    Science.gov (United States)

    Bates, Vincent C.

    2012-01-01

    This article takes a practical look at social class in school music by exploring the manifestations and impact of three of its dimensions: financial resources, cultural practices, and social networks. Three suggestions are discussed: provide a free and equal music education for all students, understand and respect each student's cultural…

  16. A Class of Graceful Trees

    Institute of Scientific and Technical Information of China (English)

    孟凡洪; 苏耕; 杨继

    2000-01-01

    The present paper shows the coordinates of a tree and its vertices, defines a kind of Trees with Odd-Number Radiant Type (TONRT), deals with the gracefulness of TONRT by using the edge-moving theorem, and uses graceful TONRT to construct another class of graceful trees.

  17. COOPERATIVE LEARNING IN LARGE CLASSES

    Institute of Scientific and Technical Information of China (English)

    GuoXiangju

    2004-01-01

    Teaching college English in large classes is a new challenge to teachers. To meet this challenge, the strategy of cooperative learning is practicable. This paper introduces cooperative learning and describes the experiment results, which prove the advantages of cooperative learning over competitive learning or individualistic learning.

  18. Active Learning in Large Classes

    DEFF Research Database (Denmark)

    Gørtz, Inge Li

    2011-01-01

    teaching large classes (more than 50 students), and describe how we successfully have in a second semester course in the Bachelor of Engineering (BEng) and Bachelor of Science Engineering (BSc Eng) program at the Technical University of Denmark (DTU). Approximately 200 students is attending the...

  19. Active Learning in Large Classes

    DEFF Research Database (Denmark)

    Gørtz, Inge Li

    2011-01-01

    lectures in the course. The main idea is to use inductive, case-based learning, with many small exercises/ discussions during the lectures. We describe a framework for the lectures, that most lectures in the class were based on. The framework contains the conceive, design, and implement stage from the CDIO...

  20. "Green" Classes Flourish in Schools

    Science.gov (United States)

    Cavanagh, Sean

    2009-01-01

    Courses focused on renewable and alternative energy are taking hold across the country as educators seek to channel students' concerns about the environment and conservation into classroom lessons. This article talks about the rising interest in "green" curriculum. Here, the author describes the Green Tech class that introduces students to the…

  1. Art of Class Teaching Encourage

    Institute of Scientific and Technical Information of China (English)

    HE Jiao-fei

    2013-01-01

    Teaching encourage can lead to student’s learning motivation and interesting. It improves the effect of classroom teach⁃ing. Methods of class teaching inspiration are: Target encourage, expectation encourage, emotional encourage, positive encourage, attribution encourage, competition encourage, caress encourage, democracy encourage, praise encourage, time encourage, check en⁃courage, questions encourage, examination encourage, score encourage, example encourage and understanding encourage.

  2. Creative Thinking in Instrumental Classes.

    Science.gov (United States)

    Priest, Thomas

    2002-01-01

    Focuses on ways to develop student creative thinking, improvisation, and composition skills in instrumental classes. Provides suggestions, such as the importance of offering students creative opportunities, supplying examples, giving control to students, and encouraging expressive integrity. Includes a bibliography of resources for developing…

  3. Some five-dimensional Bianchi type-iii string cosmological models in general relativity

    International Nuclear Information System (INIS)

    In this paper we have constructed some five-dimensional Bianchi type-III cosmological models in general relativity when source of gravitational field is a massive string. We obtained different classes of solutions by considering different functional forms of metric potentials. It is also observed that one of the models is not physically acceptable and the other models possess big-bang singularity. The physical and kinematical behaviors of the models are discussed

  4. Sınıf III malokluzyonlarında uygulanan tedavi sistemleri

    OpenAIRE

    Burcu Balos Tuncer

    2011-01-01

    Skeletal Class III malocclusion with a prognathic mandible is one of the most severe maxillofacial deformities. Esthetics and functions are strongly effected and the treatments are long and hard in these malocclusions. Mandibular prognathism or maxillary retrusion or both might cause this type of malocclusions. Treatment approaches depend on the etiology, the severity of the malocclusion and the developmental stage of the subject. In growing children facial growth modification can be...

  5. Sınıf III malokluzyonlarında uygulanan tedavi sistemleri

    OpenAIRE

    Balos Tuncer, Burcu

    2011-01-01

    Skeletal Class III malocclusion with a prognathic mandible is one of the most severe maxillofacial deformities. Esthetics and functions are strongly effected and the treatments are long and hard in these malocclusions. Mandibular prognathism or maxillary retrusion or both might cause this type of malocclusions. Treatment approaches depend on the etiology, the severity of the malocclusion and the developmental stage of the subject. In growing children facial growth modification can be an effec...

  6. Relation between Angle Class II malocclusion and deleterious oral habits

    Directory of Open Access Journals (Sweden)

    José Tarcísio Lima Ferreira

    2012-12-01

    Full Text Available INTRODUCTION: Oral habits may interfere on the growth and development of the stomatognathic system and orofacial myofunctional conditions, producing changes in the position of teeth in their dental arches. OBJECTIVE: The purpose of this study was to verify the presence of deleterious oral habits in individuals with malocclusion and see if there is a predominance of Class II malocclusion in these individuals. METHODS: The records of 140 patients treated at the Clinic of Preventive Orthodontics FORP-USP who had already completed treatment were randomly selected and analyzed. Their ages ranged from 6 to 10 years and 11 months. Associations were made between the presence or absence of deleterious oral habits, type and number of habits found in each individual and the type of malocclusion according to Angle classification. The statistical analysis used was the Chi-square test with a significance level of 5%. History of deleterious oral habits was found in 67.1% of individuals. RESULTS: The Class I malocclusion was most frequent (82.9%, followed by Class II malocclusion (12.1% and Class III (5%. CONCLUSION: There was a predominance of Class II malocclusion in individuals with a history of deleterious oral habits.INTRODUÇÃO: hábitos bucais podem interferir no crescimento e desenvolvimento do sistema estomatognático e nas condições miofuncionais bucofaciais, acarretando alterações no posicionamento dos dentes nas respectivas arcadas dentárias. OBJETIVO: o objetivo dessa pesquisa foi verificar a presença de hábitos bucais deletérios em indivíduos portadores de má oclusão e observar se existe predominância de má oclusão Classe II de Angle nesses indivíduos. MÉTODOS: foram selecionadas, aleatoriamente, e analisadas 140 fichas de pacientes atendidos na Clínica de Ortodontia Preventiva da FORP-USP, que já haviam recebido alta no tratamento. A faixa etária variou dos 6 anos a 10 anos e 11 meses. Foram realizadas associações entre

  7. Preparation of III-V semiconductor nanocrystals

    Science.gov (United States)

    Alivisatos, A. Paul; Olshavsky, Michael A.

    1996-01-01

    Nanometer-scale crystals of III-V semiconductors are disclosed, They are prepared by reacting a group III metal source with a group V anion source in a liquid phase at elevated temperature in the presence of a crystallite growth terminator such as pyridine or quinoline.

  8. Iron(III) spin crossover compounds

    NARCIS (Netherlands)

    van Koningsbruggen, PJ; Maeda, Y; Oshio, H

    2004-01-01

    In this chapter, selected results obtained so far on Fe(III) spin crossover compounds are summarized and discussed. Fe(III) spin transition materials of ligands containing chalcogen donor atoms are considered with emphasis on those of N,N-disubstituted-dithiocarbamates, N,N-disubstituted-XY-carbamat

  9. Synthesis and in vitro microbial evaluation of La(III), Ce(III), Sm(III) and Y(III) metal complexes of vitamin B6 drug

    Science.gov (United States)

    Refat, Moamen S.; Al-Azab, Fathi M.; Al-Maydama, Hussein M. A.; Amin, Ragab R.; Jamil, Yasmin M. S.

    2014-06-01

    Metal complexes of pyridoxine mono hydrochloride (vitamin B6) are prepared using La(III), Ce(III), Sm(III) and Y(III). The resulting complexes are investigated. Some physical properties, conductivity, analytical data and the composition of the four pyridoxine complexes are discussed. The elemental analysis shows that the formed complexes of La(III), Ce(III), Sm(III) and Y(III) with pyridoxine are of 1:2 (metal:PN) molar ratio. All the synthesized complexes are brown in color and possess high melting points. These complexes are partially soluble in hot methanol, dimethylsulfoxide and dimethylformamide and insoluble in water and some other organic solvents. Elemental analysis data, spectroscopic (IR, UV-vis. and florescence), effective magnetic moment in Bohr magnetons and the proton NMR suggest the structures. However, definite particle size is determined by invoking the X-ray powder diffraction and scanning electron microscopy data. The results obtained suggested that pyridoxine reacted with metal ions as a bidentate ligand through its phenolate oxygen and the oxygen of the adjacent group at the 4‧-position. The molar conductance measurements proved that the pyridoxine complexes are electrolytic in nature. The kinetic and thermodynamic parameters such as: Ea, ΔH*, ΔS* and ΔG* were estimated from the DTG curves. The antibacterial evaluation of the pyridoxine and their complexes were also performed against some gram positive, negative bacteria as well as fungi.

  10. Synthesis, spectroscopic and antimicrobial studies of La(III), Ce(III), Sm(III) and Y(III) Metformin HCl chelates

    Science.gov (United States)

    Refat, Moamen S.; Al-Azab, Fathi M.; Al-Maydama, Hussein M. A.; Amin, Ragab R.; Jamil, Yasmin M. S.; Kobeasy, Mohamed I.

    2015-05-01

    Metal complexes of Metformin hydrochloride were prepared using La(III), Ce(III), Sm(III) and Y(III). The resulting complexes were discussed and synthesized to serve as potential insulin-mimetic. Some physical properties and analytical data of the four complexes were checked. The elemental analysis shows that La(III), Ce(III) Sm(III) and Y(III) formed complexes with Metformin in 1:3 (metal:MF) molar ratio. All the synthesized complexes are white and possess high melting points. These complexes are soluble in dimethylsulfoxide and dimethylformamide, partially soluble in hot methanol and insoluble in water and some other organic solvents. From the spectroscopic (infrared, UV-vis and florescence), effective magnetic moment and elemental analyses data, the formula structures are suggested. The results obtained suggested that Metformin reacted with metal ions as a bidentate ligand through its two imino groups. The molar conductance measurements proved that the Metformin complexes are slightly electrolytic in nature. The kinetic thermodynamic parameters such as: E∗, ΔH∗, ΔS∗ and ΔG∗ were estimated from the DTG curves. The antibacterial evaluations of the Metformin and their complexes were also performed against some gram positive, negative bacteria as well as fungi.

  11. Student versus Faculty Perceptions of Missing Class.

    Science.gov (United States)

    Sleigh, Merry J.; Ritzer, Darren R.; Casey, Michael B.

    2002-01-01

    Examines and compares student and faculty attitudes towards students missing classes and class attendance. Surveys undergraduate students (n=231) in lower and upper level psychology courses and psychology faculty. Reports that students found more reasons acceptable for missing classes and that the amount of in-class material on the examinations…

  12. Education, Social Class and Social Exclusion.

    Science.gov (United States)

    Whitty, Geoff

    2001-01-01

    Concerned about working-class failure, argues that recent (British) government policies have insufficiently considered sociological studies on how social class affects educational success or failure. Social-inclusion policies must address forms of middle-class self-exclusion from mainstream public education as well as working-class social…

  13. Making the Introductory Journalism Class Tick.

    Science.gov (United States)

    Dorway, Tim

    2003-01-01

    Proposes that beginning journalism classes teach multiple skills, including law, decision-making, interpersonal communication, interviewing, and critical thinking. Outlines how to convince administrators of the need for beginning journalism classes, and how to develop an effective class. Lists philosophy and course goals for one such class. (PM)

  14. BDDCS Class Prediction for New Molecular Entities

    DEFF Research Database (Denmark)

    Broccatelli, Fabio; Cruciani, Gabriele; Benet, Leslie Z.;

    2012-01-01

    the prediction, which showed highest accuracy in predicting classes 2 and 3 with respect to the most populated class 1. For class 4 drugs a general lack of predictability was observed. A linear discriminant analysis (LDA) confirming the degree of accuracy for the prediction of the different BDDCS classes is tied...

  15. Trabalho e classes sociais Work and social classes

    Directory of Open Access Journals (Sweden)

    Fernando Haddad

    1997-10-01

    Full Text Available Exposição, discussão e refutação das principais tentativas de atualizar a teoria marxista de classes e posterior reavaliação dessa teoria à luz da transformação da ciência em fator de produção e da possível perda de centralidade do trabalho no processo produtivo, tendo por base as interpretações lógicas da obra de Marx feitas por Ruy Fausto.Exposition, discussion and refutation of the main attempts of actualizing marxist class theory and a posterior reevaluation of this theory taking into account the transformation of Science into a factor of production and of the possible centrality-loss of work in the productive process, based on the logic interpretations of Marx's work made by Ruy Fausto.

  16. Stochastic prediction of drought class transitions

    OpenAIRE

    Paulo, Ana A.; L. S. Pereira

    2008-01-01

    This paper aims at the stochastic characterization of droughts applying Markov chains modeling to drought class transitions derived from SPI time series. Several sites in Southern Portugal having updated data on precipitation available were considered. The drought class probabilities, the expected residence time in each class of severity, the expected time for the transition between drought classes and the drought severity class predictions 1, 2, or 3 months ahead have been obt...

  17. Understanding Intra-Class Knowledge Inside CNN

    OpenAIRE

    Wei, Donglai; Zhou, Bolei; Torrabla, Antonio; Freeman, William

    2015-01-01

    Convolutional Neural Network (CNN) has been successful in image recognition tasks, and recent works shed lights on how CNN separates different classes with the learned inter-class knowledge through visualization. In this work, we instead visualize the intra-class knowledge inside CNN to better understand how an object class is represented in the fully-connected layers. To invert the intra-class knowledge into more interpretable images, we propose a non-parametric patch prior upon previous CNN...

  18. A Transformer Class E Amplifier

    Directory of Open Access Journals (Sweden)

    Mikolajewski Miroslaw

    2014-12-01

    Full Text Available In a high-efficiency Class E ZVS resonant amplifier a matching and isolation transformer can replace some or even all inductive components of the amplifier thus simplifying the circuit and reducing its cost. In the paper a theoretical analysis, a design example and its experimental verification for a transformer Class E amplifier are presented. In the experimental amplifier with a transformer as the only inductive component in the circuit high efficiency ηMAX = 0.95 was achieved for supply voltage VI = 36 V, maximum output power POMAX = 100 W and the switching frequency f = 300 kHz. Measured parameters and waveforms showed a good agreement with theoretical predictions. Moreover, the relative bandwidth of the switching frequency was only 19% to obtain output power control from 4.8 W to POMAX with efficiency not less than 0.9 in the regulation range.

  19. The Fermilab physics class library

    International Nuclear Information System (INIS)

    The Fermilab Physics Class Library Task Force has been formed to supply classes and utilities, primarily in support of efforts by CDF and D0 toward using C++. A collection of libraries and tools will be assembled via development by the task force, collaboration with other HEP developers, and acquisition of existing modules. The main emphasis is on a kit of resources which physics coders can incorporate into their programs, with confidence in robustness and correct behavior. The task force is drawn from CDF, DO and the FNAL Computing and Beams Divisions. Modules-containers, linear algebra, histograms, etc.-have been assigned priority, based on immediate Run II coding activity, and will be available at times ranging from now to late May

  20. European Energy Law. Report III

    International Nuclear Information System (INIS)

    The European Energy Law Report III presents an overview of the most important legal developments in the field of EU and national energy law as discussed at the 2005 European Energy Law Seminar. It examines the Commission's recent progress report on the implementation of the 2003 energy directives, its sector inquiry regarding competition conditions in the energy markets, and its recent policy on vertical and conglomerate mergers in the light of its ongoing concern as to the increased levels of concentration in Europe's energy markets. The investigation of the Bundeskartellamt in Germany concerns the role of long-term downstream gas supply agreements in a liberalised market. Regulators are increasingly confronted with the need to secure the quality of electricity supply in a competitive market. After an analysis of how electricity distribution companies can be regulated with respect to quality of supply, separate chapters from Italy and the Netherlands discuss national developments in detail. The role of LNG is increasing in the European gas market. The book discusses the main components of the short-term LNG sale and purchase agreements, the rules regarding non-discriminatory access to existing regasification terminals as well as the establishment of new LNG import terminals in the EU and the extent to which such installations can be exempted from the applicable regime on regulated third-party access. The book examines several legal developments regarding energy infrastructure. Whereas the 2003 energy directives provide for a legal unbundling of the downstream energy transmission and distribution companies, some Member States (Denmark and the Netherlands) go beyond this requirement and have introduced ownership unbundling in order to guarantee the establishment of an independent system operator. Recent developments in the North Sea include the establishment of a Framework Agreement, aiming at a simplification of rules and procedures for new projects across the UK