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Sample records for cis-element analyses point

  1. The twilight zone of cis element alignments.

    Science.gov (United States)

    Sebastian, Alvaro; Contreras-Moreira, Bruno

    2013-02-01

    Sequence alignment of proteins and nucleic acids is a routine task in bioinformatics. Although the comparison of complete peptides, genes or genomes can be undertaken with a great variety of tools, the alignment of short DNA sequences and motifs entails pitfalls that have not been fully addressed yet. Here we confront the structural superposition of transcription factors with the sequence alignment of their recognized cis elements. Our goals are (i) to test TFcompare (http://floresta.eead.csic.es/tfcompare), a structural alignment method for protein-DNA complexes; (ii) to benchmark the pairwise alignment of regulatory elements; (iii) to define the confidence limits and the twilight zone of such alignments and (iv) to evaluate the relevance of these thresholds with elements obtained experimentally. We find that the structure of cis elements and protein-DNA interfaces is significantly more conserved than their sequence and measures how this correlates with alignment errors when only sequence information is considered. Our results confirm that DNA motifs in the form of matrices produce better alignments than individual sequences. Finally, we report that empirical and theoretically derived twilight thresholds are useful for estimating the natural plasticity of regulatory sequences, and hence for filtering out unreliable alignments.

  2. Bioinformatic identification of novel putative photoreceptor specific cis-elements

    OpenAIRE

    Knox Barry E; Qin Maochun; McIlvain Vera A; Danko Charles G; Pertsov Arkady M

    2007-01-01

    Abstract Background Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However, experimental detection of cis-elements is difficult, expensive, and time-consuming. This provides a motivation for developing bioinformatic methods to identify cis-elements that could prioritize future experimental studies. Here, we use motif discovery algorithms to predict transcription factor binding site...

  3. Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation

    DEFF Research Database (Denmark)

    Stegmann, Anders; Hansen, Morten; Wang, Yulan;

    2006-01-01

    DNA-binding transcription factors bind to promoters that carry their binding sites. Transcription factors therefore function as nodes in gene regulatory networks. In the present work we used a bioinformatic approach to search for transcription factors that might function as nodes in gene regulatory...

  4. Bioinformatic cis-element analyses performed in Arabidopsis and rice disclose bZIP- and MYB-related binding sites as potential AuxRE-coupling elements in auxin-mediated transcription

    Directory of Open Access Journals (Sweden)

    Berendzen Kenneth W

    2012-08-01

    Full Text Available Abstract Background In higher plants, a diverse array of developmental and growth-related processes is regulated by the plant hormone auxin. Recent publications have proposed that besides the well-characterized Auxin Response Factors (ARFs that bind Auxin Response Elements (AuxREs, also members of the bZIP- and MYB-transcription factor (TF families participate in transcriptional control of auxin-regulated genes via bZIP Response Elements (ZREs or Myb Response Elements (MREs, respectively. Results Applying a novel bioinformatic algorithm, we demonstrate on a genome-wide scale that singular motifs or composite modules of AuxREs, ZREs, MREs but also of MYC2 related elements are significantly enriched in promoters of auxin-inducible genes. Despite considerable, species-specific differences in the genome structure in terms of the GC content, this enrichment is generally conserved in dicot (Arabidopsis thaliana and monocot (Oryza sativa model plants. Moreover, an enrichment of defined composite modules has been observed in selected auxin-related gene families. Consistently, a bipartite module, which encompasses a bZIP-associated G-box Related Element (GRE and an AuxRE motif, has been found to be highly enriched. Making use of transient reporter studies in protoplasts, these findings were experimentally confirmed, demonstrating that GREs functionally interact with AuxREs in regulating auxin-mediated transcription. Conclusions Using genome-wide bioinformatic analyses, evolutionary conserved motifs have been defined which potentially function as AuxRE-dependent coupling elements to establish auxin-specific expression patterns. Based on these findings, experimental approaches can be designed to broaden our understanding of combinatorial, auxin-controlled gene regulation.

  5. Modeling an evolutionary conserved circadian cis-element.

    Directory of Open Access Journals (Sweden)

    Eric R Paquet

    2008-02-01

    Full Text Available Circadian oscillator networks rely on a transcriptional activator called CLOCK/CYCLE (CLK/CYC in insects and CLOCK/BMAL1 or NPAS2/BMAL1 in mammals. Identifying the targets of this heterodimeric basic-helix-loop-helix (bHLH transcription factor poses challenges and it has been difficult to decipher its specific sequence affinity beyond a canonical E-box motif, except perhaps for some flanking bases contributing weakly to the binding energy. Thus, no good computational model presently exists for predicting CLK/CYC, CLOCK/BMAL1, or NPAS2/BMAL1 targets. Here, we use a comparative genomics approach and first study the conservation properties of the best-known circadian enhancer: a 69-bp element upstream of the Drosophila melanogaster period gene. This fragment shows a signal involving the presence of two closely spaced E-box-like motifs, a configuration that we can also detect in the other four prominent CLK/CYC target genes in flies: timeless, vrille, Pdp1, and cwo. This allows for the training of a probabilistic sequence model that we test using functional genomics datasets. We find that the predicted sequences are overrepresented in promoters of genes induced in a recent study by a glucocorticoid receptor-CLK fusion protein. We then scanned the mouse genome with the fly model and found that many known CLOCK/BMAL1 targets harbor sequences matching our consensus. Moreover, the phase of predicted cyclers in liver agreed with known CLOCK/BMAL1 regulation. Taken together, we built a predictive model for CLK/CYC or CLOCK/BMAL1-bound cis-enhancers through the integration of comparative and functional genomics data. Finally, a deeper phylogenetic analysis reveals that the link between the CLOCK/BMAL1 complex and the circadian cis-element dates back to before insects and vertebrates diverged.

  6. Identification of a Positive Cis-Element Upstream of Human NKX3.1 Gene

    Institute of Scientific and Technical Information of China (English)

    An-Li JIANG; Peng-Ju ZHANG; Xiao-Yan HU; Wei-Wen CHEN; Feng KONG; Zhi-Fang LIU; Hui-Qing YUAN; Jian-Ye ZHANG

    2005-01-01

    NKX3.1 is a prostate-specific homeobox gene related to prostate development and prostate cancer. In this work, we aimed to identify precisely the functional cis-element in the 197 bp region (from -1032 to -836 bp) of the NKX3.1 promoter (from -1032 to +8 bp), which was previously identified to present positive regulatory activity on NKX3.1 expression, by deletion mutagenesis analysis and electrophoretic mobility shift assay (EMSA). A 16 bp positive cis-element located between -920 and -905 bp upstream of the NKX3.1 gene was identified by deletion mutation analysis and proved to be a functional positive cis-element by EMSA. It will be important to further study the functions and regulatory mechanisms of this positive cis-element in NKX3.1 gene expression.

  7. Solid Phase Biosensors for Arsenic or Cadmium Composed of A trans Factor and cis Element Complex

    Directory of Open Access Journals (Sweden)

    Mohammad Shohel Rana Siddiki

    2011-10-01

    Full Text Available The presence of toxic metals in drinking water has hazardous effects on human health. This study was conducted to develop GFP-based-metal-binding biosensors for on-site assay of toxic metal ions. GFP-tagged ArsR and CadC proteins bound to a cis element, and lost the capability of binding to it in their As- and Cd-binding conformational states, respectively. Water samples containing toxic metals were incubated on a complex of GFP-tagged ArsR or CadC and cis element which was immobilized on a solid surface. Metal concentrations were quantified with fluorescence intensity of the metal-binding states released from the cis element. Fluorescence intensity obtained with the assay significantly increased with increasing concentrations of toxic metals. Detection limits of 1 μg/L for Cd(II and 5 μg/L for As(III in purified water and 10 µg/L for Cd(II and As(III in tap water and bottled mineral water were achieved by measurement with a battery-powered portable fluorometer after 15-min and 30-min incubation, respectively. A complex of freeze dried GFP-tagged ArsR or CadC binding to cis element was stable at 4 °C and responded to 5 μg/L As(III or Cd(II. The solid phase biosensors are sensitive, less time-consuming, portable, and could offer a protocol for on-site evaluation of the toxic metals in drinking water.

  8. Solid phase biosensors for arsenic or cadmium composed of A trans factor and cis element complex.

    Science.gov (United States)

    Siddiki, Mohammad Shohel Rana; Kawakami, Yasunari; Ueda, Shunsaku; Maeda, Isamu

    2011-01-01

    The presence of toxic metals in drinking water has hazardous effects on human health. This study was conducted to develop GFP-based-metal-binding biosensors for on-site assay of toxic metal ions. GFP-tagged ArsR and CadC proteins bound to a cis element, and lost the capability of binding to it in their As- and Cd-binding conformational states, respectively. Water samples containing toxic metals were incubated on a complex of GFP-tagged ArsR or CadC and cis element which was immobilized on a solid surface. Metal concentrations were quantified with fluorescence intensity of the metal-binding states released from the cis element. Fluorescence intensity obtained with the assay significantly increased with increasing concentrations of toxic metals. Detection limits of 1 μg/L for Cd(II) and 5 μg/L for As(III) in purified water and 10 µg/L for Cd(II) and As(III) in tap water and bottled mineral water were achieved by measurement with a battery-powered portable fluorometer after 15-min and 30-min incubation, respectively. A complex of freeze dried GFP-tagged ArsR or CadC binding to cis element was stable at 4 °C and responded to 5 μg/L As(III) or Cd(II). The solid phase biosensors are sensitive, less time-consuming, portable, and could offer a protocol for on-site evaluation of the toxic metals in drinking water. PMID:22346629

  9. A New Approach to Sequence Analysis Exemplified by Identification of cis-Elements in Abscisic Acid Inducible Promoters

    DEFF Research Database (Denmark)

    Busk, Peter Kamp; Hallin, Peter Fischer; Salomon, Jesper;

    Identification of cis-regulatory elements in DNA promoters by computational approaches are a great help in genome-wide elucidation of signal transduction, transcriptional regulation and gene expression. However, to accomplish this has proven a difficult problem in computational genomics in part due...... the sequences of known cis-elements for promoter prediction4. This is a computational alternative to genome-wide DNA array analysis of gene expression and can be used to confirm the importance of known promoter elements on a genome level. Unfortunately, this approach does not yield information about new cis...... to the redundant nature of cis-regulatory elements1. Moreover, promoter context and chromatin structure have an important influence on the function of cis-elements and does further complicate the identification of functional cis-elements2,3. A related computational approach to promoter studies is to use...

  10. Analysing Music with Point-Set Compression Algorithms

    DEFF Research Database (Denmark)

    Meredith, David

    2016-01-01

    Several point-set pattern-discovery and compression algorithms designed for analysing music are reviewed and evaluated. Each algorithm takes as input a point-set representation of a score in which each note is represented as a point in pitch-time space. Each algorithm computes the maximal...... in pitch-time space to give other patterns in the input dataset. Encoding TECs in this way leads, in general, to compression, since each occurrence of a pattern within a TEC (apart from one) is encoded by a single vector, that has the same information content as one point. The algorithms reviewed here...... adopt different strategies aimed at selecting a set of MTP TECs that collectively cover (or almost cover) the input dataset in a way that maximizes compression. The algorithms are evaluated on two musicological tasks: classifying folk song melodies into tune families and discovering repeated themes...

  11. Transient Point Source Analyses in the ANTARES Neutrino Telescope

    CERN Document Server

    Sánchez-Losa, Agustín

    2013-01-01

    The ANTARES telescope, with a duty cycle close to unity and a full hemisphere of the sky at all the times visible, is well suited to detect neutrinos produced in astrophysical transient sources. Assuming a known neutrino production period, the background and the sensitivity can be drastically improved by selecting a narrow time window around it. GRBs, {\\mu}-quasars and AGNs are particularly attractive potential neutrino point sources since neutrinos and gamma-rays may be produced in hadronic interactions with the surrounding medium as they are the most likely sources of the observed ultra high energy cosmic rays. A strong correlation between the gamma-ray and the neutrino fluxes is expected in this scenario. ANTARES data has been analysed in various transient source analyses with the goal of detecting cosmic neutrinos from GRBs, {\\mu}-quasars and AGNs. The sensitivity of a standard time-integrated point source search can be improved by a factor 2-3 by looking for neutrinos only during the most probable emissi...

  12. Identification of a peroxisome proliferator responsive element (PPRE)-like cis-element in mouse plasminogen activator inhibitor-1 gene promoter

    International Nuclear Information System (INIS)

    PAI-1 is expressed and secreted by adipose tissue which may mediate the pathogenesis of obesity-associated cardiovascular complications. Evidence is presented in this report that PAI-1 is not expressed by preadipocyte, but significantly induced during 3T3-L1 adipocyte differentiation and the PAI-1 expression correlates with the induction of peroxisome proliferator-activated receptor γ (PPARγ). A peroxisome proliferator responsive element (PPRE)-like cis-element (-206TCCCCCATGCCCT-194) is identified in the mouse PAI-1 gene promoter by electrophoretic mobility shift assay (EMSA) combined with transient transfection experiments; the PPRE-like cis-element forms a specific DNA-protein complex only with adipocyte nuclear extracts, not with preadipocyte nuclear extracts; the DNA-protein complex can be totally competed away by non-labeled consensus PPRE, and can be supershifted with PPARγ antibody. Mutation of this PPRE-like cis-element can abolish the transactivation of mouse PAI-1 promoter mediated by PPARγ. Specific PPARγ ligand Pioglitazone can significantly induce the PAI-1 expression, and stimulate the secretion of PAI-1 into medium

  13. Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation

    Directory of Open Access Journals (Sweden)

    Lundberg Cathryn

    2008-01-01

    specific cis-acting target sites which may collectively play a role in the differential gene expression patterns observed in ER+ versus ER- breast cancer tumors. Importantly, the gene sets and associated DNA motifs provide a starting point with which to explore the mechanistic basis for the observed expression patterns in breast tumors.

  14. CstF-64 and 3′-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα

    Science.gov (United States)

    Kandala, Divya T.; Mohan, Nimmy; A, Vivekanand; AP, Sudheesh; G, Reshmi; Laishram, Rakesh S.

    2016-01-01

    Almost all eukaryotic mRNAs have a poly (A) tail at the 3′-end. Canonical PAPs (PAPα/γ) polyadenylate nuclear pre-mRNAs. The recent identification of the non-canonical Star-PAP revealed specificity of nuclear PAPs for pre-mRNAs, yet the mechanism how Star-PAP selects mRNA targets is still elusive. Moreover, how Star-PAP target mRNAs having canonical AAUAAA signal are not regulated by PAPα is unclear. We investigate specificity mechanisms of Star-PAP that selects pre-mRNA targets for polyadenylation. Star-PAP assembles distinct 3′-end processing complex and controls pre-mRNAs independent of PAPα. We identified a Star-PAP recognition nucleotide motif and showed that suboptimal DSE on Star-PAP target pre-mRNA 3′-UTRs inhibit CstF-64 binding, thus preventing PAPα recruitment onto it. Altering 3′-UTR cis-elements on a Star-PAP target pre-mRNA can switch the regulatory PAP from Star-PAP to PAPα. Our results suggest a mechanism of poly (A) site selection that has potential implication on the regulation of alternative polyadenylation. PMID:26496945

  15. CstF-64 and 3'-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα.

    Science.gov (United States)

    Kandala, Divya T; Mohan, Nimmy; A, Vivekanand; A P, Sudheesh; G, Reshmi; Laishram, Rakesh S

    2016-01-29

    Almost all eukaryotic mRNAs have a poly (A) tail at the 3'-end. Canonical PAPs (PAPα/γ) polyadenylate nuclear pre-mRNAs. The recent identification of the non-canonical Star-PAP revealed specificity of nuclear PAPs for pre-mRNAs, yet the mechanism how Star-PAP selects mRNA targets is still elusive. Moreover, how Star-PAP target mRNAs having canonical AAUAAA signal are not regulated by PAPα is unclear. We investigate specificity mechanisms of Star-PAP that selects pre-mRNA targets for polyadenylation. Star-PAP assembles distinct 3'-end processing complex and controls pre-mRNAs independent of PAPα. We identified a Star-PAP recognition nucleotide motif and showed that suboptimal DSE on Star-PAP target pre-mRNA 3'-UTRs inhibit CstF-64 binding, thus preventing PAPα recruitment onto it. Altering 3'-UTR cis-elements on a Star-PAP target pre-mRNA can switch the regulatory PAP from Star-PAP to PAPα. Our results suggest a mechanism of poly (A) site selection that has potential implication on the regulation of alternative polyadenylation. PMID:26496945

  16. Arabidopsis miR171-targeted scarecrow-like proteins bind to GT cis-elements and mediate gibberellin-regulated chlorophyll biosynthesis under light conditions.

    Science.gov (United States)

    Ma, Zhaoxue; Hu, Xupeng; Cai, Wenjuan; Huang, Weihua; Zhou, Xin; Luo, Qian; Yang, Hongquan; Wang, Jiawei; Huang, Jirong

    2014-08-01

    An extraordinarily precise regulation of chlorophyll biosynthesis is essential for plant growth and development. However, our knowledge on the complex regulatory mechanisms of chlorophyll biosynthesis is very limited. Previous studies have demonstrated that miR171-targeted scarecrow-like proteins (SCL6/22/27) negatively regulate chlorophyll biosynthesis via an unknown mechanism. Here we showed that SCLs inhibit the expression of the key gene encoding protochlorophyllide oxidoreductase (POR) in light-grown plants, but have no significant effect on protochlorophyllide biosynthesis in etiolated seedlings. Histochemical analysis of β-glucuronidase (GUS) activity in transgenic plants expressing pSCL27::rSCL27-GUS revealed that SCL27-GUS accumulates at high levels and suppresses chlorophyll biosynthesis at the leaf basal proliferation region during leaf development. Transient gene expression assays showed that the promoter activity of PORC is indeed regulated by SCL27. Consistently, chromatin immunoprecipitation and quantitative PCR assays showed that SCL27 binds to the promoter region of PORC in vivo. An electrophoretic mobility shift assay revealed that SCL27 is directly interacted with G(A/G)(A/T)AA(A/T)GT cis-elements of the PORC promoter. Furthermore, genetic analysis showed that gibberellin (GA)-regulated chlorophyll biosynthesis is mediated, at least in part, by SCLs. We demonstrated that SCL27 interacts with DELLA proteins in vitro and in vivo by yeast-two-hybrid and coimmunoprecipitation analysis and found that their interaction reduces the binding activity of SCL27 to the PORC promoter. Additionally, we showed that SCL27 activates MIR171 gene expression, forming a feedback regulatory loop. Taken together, our data suggest that the miR171-SCL module is critical for mediating GA-DELLA signaling in the coordinate regulation of chlorophyll biosynthesis and leaf growth in light.

  17. Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells.

    Directory of Open Access Journals (Sweden)

    Jerome E Lee

    Full Text Available BACKGROUND: Dramatic changes in gene expression occur in response to extracellular stimuli and during differentiation. Although transcriptional effects are important, alterations in mRNA decay also play a major role in achieving rapid and massive changes in mRNA abundance. Moreover, just as transcription factor activity varies between different cell types, the factors influencing mRNA decay are also cell-type specific. PRINCIPAL FINDINGS: We have established the rates of decay for over 7000 transcripts expressed in mouse C2C12 myoblasts. We found that GU-rich (GRE and AU-rich (ARE elements are over-represented in the 3'UTRs of short-lived mRNAs and that these mRNAs tend to encode factors involved in cell cycle and transcription regulation. Stabilizing elements were also identified. By comparing mRNA decay rates in C2C12 cells with those previously measured for pluripotent and differentiating embryonic stem (ES cells, we identified several groups of transcripts that exhibit cell-type specific decay rates. Further, whereas in C2C12 cells the impact of GREs on mRNA decay appears to be greater than that of AREs, AREs are more significant in ES cells, supporting the idea that cis elements make a cell-specific contribution to mRNA stability. GREs are recognized by CUGBP1, an RNA-binding protein and instability factor whose function is affected in several neuromuscular diseases. We therefore utilized RNA immunoprecipitation followed by microarray (RIP-Chip to identify CUGBP1-associated transcripts. These mRNAs also showed dramatic enrichment of GREs in their 3'UTRs and encode proteins linked with cell cycle, and intracellular transport. Interestingly several CUGBP1 substrate mRNAs, including those encoding the myogenic transcription factors Myod1 and Myog, are also bound by the stabilizing factor HuR in C2C12 cells. Finally, we show that several CUGBP1-associated mRNAs containing 3'UTR GREs, including Myod1, are stabilized in cells depleted of CUGBP1

  18. Experimental and theoretical analyses of package-on-package structure under three-point bending loading

    Institute of Scientific and Technical Information of China (English)

    Jia Su; Wang Xi-Shu; Ren Huai-Hui

    2012-01-01

    High density packaging is developing toward miniaturization and integration,which causes many difficulties in designing,manufacturing,and reliability testing.Package-on-Package (PoP) is a promising three-dimensional high-density packaging method that integrates a chip scale package (CSP) in the top package and a fine-pitch ball grid array (FBGA) in the bottom package.In this paper,in-situ scanning electron microscopy (SEM) observation is carried out to detect the deformation and damage of the PoP structure under three-point bending loading.The results iudicate that the cracks occur in the die of the top package,then cause the crack deflection and bridging in the die attaching layer.Furthermore,the mechanical principles are used to analyse the cracking process of the PoP structure based on the multi-layer laminating hypothesis and the theoretical analysis results are found to be in good agreement with the experimental results.

  19. The Extraction of Vegetation Points from LiDAR Using 3D Fractal Dimension Analyses

    Directory of Open Access Journals (Sweden)

    Haiquan Yang

    2015-08-01

    Full Text Available Light Detection and Ranging (LiDAR, a high-precision technique used for acquiring three-dimensional (3D surface information, is widely used to study surface vegetation information. Moreover, the extraction of a vegetation point set from the LiDAR point cloud is a basic starting-point for vegetation information analysis, and an important part of its further processing. To extract the vegetation point set completely and to describe the different spatial morphological characteristics of various features in a LiDAR point cloud, we have used 3D fractal dimensions. We discovered that every feature has its own distinctive 3D fractal dimension interval. Based on the 3D fractal dimensions of tall trees, we propose a new method for the extraction of vegetation using airborne LiDAR. According to this method, target features can be distinguished based on their morphological characteristics. The non-ground points acquired by filtering are processed by region growing segmentation and the morphological characteristics are evaluated by 3D fractal dimensions to determine the features required for the determination of the point set for tall trees. Avon, New York, USA was selected as the study area to test the method and the result proves the method’s efficiency. Thus, this approach is feasible. Additionally, the method uses the 3D coordinate properties of the LiDAR point cloud and does not require additional information, such as return intensity, giving it a larger scope of application.

  20. EULAR points to consider when establishing, analysing and reporting safety data of biologics registers in rheumatology

    DEFF Research Database (Denmark)

    Dixon, William G; Carmona, Loreto; Finckh, Axel;

    2010-01-01

    upon safety data generated from observational drug registers makes it important to convert the lessons learned from such registers into recommendations for rheumatologists embarking upon the establishment of future registers, or analysing and reporting from new and existing registers....

  1. Reliability of an experimental method to analyse the impact point on a golf ball during putting.

    Science.gov (United States)

    Richardson, Ashley K; Mitchell, Andrew C S; Hughes, Gerwyn

    2015-06-01

    This study aimed to examine the reliability of an experimental method identifying the location of the impact point on a golf ball during putting. Forty trials were completed using a mechanical putting robot set to reproduce a putt of 3.2 m, with four different putter-ball combinations. After locating the centre of the dimple pattern (centroid) the following variables were tested; distance of the impact point from the centroid, angle of the impact point from the centroid and distance of the impact point from the centroid derived from the X, Y coordinates. Good to excellent reliability was demonstrated in all impact variables reflected in very strong relative (ICC = 0.98-1.00) and absolute reliability (SEM% = 0.9-4.3%). The highest SEM% observed was 7% for the angle of the impact point from the centroid. In conclusion, the experimental method was shown to be reliable at locating the centroid location of a golf ball, therefore allowing for the identification of the point of impact with the putter head and is suitable for use in subsequent studies. PMID:26102559

  2. L'analyse de l'expertise du point de vue de l'ergonomie cognitive

    CERN Document Server

    Visser, Willemien

    2006-01-01

    This paper presents a review of methods for collecting and analysing data on complex activities. Starting with methods developed for design, we examine the possibility to transpose them to other complex activities, especially activities referring to sensorial expertise. ----- R\\'esum\\'e Ce texte pr\\'esente une revue de m\\'ethodes pour recueillir et analyser des donn\\'ees sur des actvit\\'es complexes. A partir de m\\'ethodes d\\'evelopp\\'ees pour des actvit\\'es de conception, nous examinons la possibilit\\'e de les transposer \\`a d'autres actvit\\'es complexes, notamment des actvit\\'es faisant \\`a appel \\`a des expertises sensorielles.

  3. Smooth-operating point and theoretical analyses of unsmooth operation in pyrological processes

    Directory of Open Access Journals (Sweden)

    Wenqiang Sun, Jiuju Cai, Fangmin Quan, Shizheng Ren

    2010-11-01

    Full Text Available To emphasize the role of heat loss in energy conservation, this paper introduces smooth operation principle. By least square method, the smooth-operating point (SOP formula of fuel gas with definite composition and temperature is deduced, which is then used to analyze changes in heat effect when injecting heat at unsmooth-operating point (UOP, educe allocation regulations of heat effect in furnace, and study the heat loss resulting from unsmooth operation. It indicates that for fuel gas with definite composition and temperature, the SOP is unique and there is no heat loss if injecting heat at SOP. With regard to unsmooth operation, low UOP is better than a high one.

  4. Det-Det correlations for quantum maps: Dual pair and saddle-point analyses

    International Nuclear Information System (INIS)

    An attempt is made to clarify the ballistic nonlinear sigma model formalism recently proposed for quantum chaotic systems, by looking at the spectral determinant Z(s)=Det(1-sU) for quantized maps U(set-membership sign)U(N), and studying the correlator ωU(s)=∫dθ vertical bar Z(eiθs) vertical bar2. By identifying U(N) as one member of a dual pair acting in the spinor representation of Spin(4N), the expansion of ωU(s) in powers of s2 is shown to be a decomposition into irreducible characters of U(N). In close analogy with the ballistic nonlinear sigma model, a coherent-state integral representation of ωU(s) is developed. For generic U this integral has (N2N) saddle points and the leading-order saddle-point approximation turns out to reproduce ωU(s) exactly, up to a constant factor. This miracle is explained by interpreting ωU(s) as a character of U(2N), and arguing that the leading-order saddle-point result corresponds to the Weyl character formula. Unfortunately, the Weyl decomposition behaves nonsmoothly in the semiclassical limit N→∞, and to make further progress some additional averaging needs to be introduced. Several schemes are investigated, including averaging over basis states and an ''isotropic'' average. The saddle-point approximation applied in conjunction with these schemes is demonstrated to give incorrect results in general, one notable exception being a semiclassical averaging scheme, for which all loop corrections vanish identically. As a side product of the dual pair decomposition with isotropic averaging, the crossover between the Poisson and CUE limits is obtained

  5. Analyses of methyltransferases across the pathogenicity spectrum of different mycobacterial species point to an extremophile connection.

    Science.gov (United States)

    Grover, Sonam; Gupta, Paras; Kahlon, Parvinderdeep S; Goyal, Sukriti; Grover, Abhinav; Dalal, Kuldeep; Sabeeha; Ehtesham, Nasreen Z; Hasnain, Seyed E

    2016-05-26

    Tuberculosis is a devastating disease, taking one human life every 20 seconds globally. We hypothesize that professional pathogens such as M.tb have acquired specific features that might assist in causing infection, persistence and transmissible pathology in their host. We have identified 121 methyltransferases (MTases) in the M.tb proteome, which use a variety of substrates - DNA, RNA, protein, intermediates of mycolic acid biosynthesis and other fatty acids - that are involved in cellular maintenance within the host. A comparative analysis of the proteome of the virulent strain H37Rv and the avirulent strain H37Ra identified 3 MTases, which displayed significant variations in terms of N-terminal extension/deletion and point mutations, possibly impacting various physicochemical properties. The cross-proteomic comparison of MTases of M.tb H37Rv with 15 different Mycobacterium species revealed the acquisition of novel MTases in a MTB complex as a function of evolution. Phylogenetic analysis revealed that these newly acquired MTases showed common roots with certain extremophiles such as halophilic and acidophilic organisms. Our results establish an evolutionary relationship of M.tb with halotolerant organisms and also the role of MTases of M.tb in withstanding the host osmotic stress, thereby pointing to their likely role in pathogenesis, virulence and niche adaptation. PMID:26983646

  6. Point processes statistics of stable isotopes: analysing water uptake patterns in a mixed stand of Aleppo pine and Holm oak

    Directory of Open Access Journals (Sweden)

    Carles Comas

    2015-04-01

    Full Text Available Aim of study: Understanding inter- and intra-specific competition for water is crucial in drought-prone environments. However, little is known about the spatial interdependencies for water uptake among individuals in mixed stands. The aim of this work was to compare water uptake patterns during a drought episode in two common Mediterranean tree species, Quercus ilex L. and Pinus halepensis Mill., using the isotope composition of xylem water (δ18O, δ2H as hydrological marker. Area of study: The study was performed in a mixed stand, sampling a total of 33 oaks and 78 pines (plot area= 888 m2. We tested the hypothesis that both species uptake water differentially along the soil profile, thus showing different levels of tree-to-tree interdependency, depending on whether neighbouring trees belong to one species or the other. Material and Methods: We used pair-correlation functions to study intra-specific point-tree configurations and the bivariate pair correlation function to analyse the inter-specific spatial configuration. Moreover, the isotopic composition of xylem water was analysed as a mark point pattern. Main results: Values for Q. ilex (δ18O = –5.3 ± 0.2‰, δ2H = –54.3 ± 0.7‰ were significantly lower than for P. halepensis (δ18O = –1.2 ± 0.2‰, δ2H = –25.1 ± 0.8‰, pointing to a greater contribution of deeper soil layers for water uptake by Q. ilex. Research highlights: Point-process analyses revealed spatial intra-specific dependencies among neighbouring pines, showing neither oak-oak nor oak-pine interactions. This supports niche segregation for water uptake between the two species.

  7. Sensitivity analyses of the theoretical equations used in point velocity probe (PVP) data interpretation

    Science.gov (United States)

    Devlin, J. F.

    2016-09-01

    Point velocity probes (PVPs) are dedicated, relatively low-cost instruments for measuring groundwater speed and direction in non-cohesive, unconsolidated porous media aquifers. They have been used to evaluate groundwater velocity in groundwater treatment zones, glacial outwash aquifers, and within streambanks to assist with the assessment of groundwater-surfaced water exchanges. Empirical evidence of acceptable levels of uncertainty for these applications has come from both laboratory and field trials. This work extends previous assessments of the method by examining the inherent uncertainties arising from the equations used to interpret PVP datasets. PVPs operate by sensing tracer movement on the probe surface, producing apparent velocities from two detectors. Sensitivity equations were developed for the estimation of groundwater speed, v∞, and flow direction, α, as a function of the apparent velocities of water on the probe surface and the α angle itself. The resulting estimations of measurement uncertainty, which are inherent limitations of the method, apply to idealized, homogeneous porous media, which on the local scale of a PVP measurement may be approached. This work does not address experimental sources of error that may arise from the presence of cohesive sediments that prevent collapse around the probe, the effects of centimeter-scale aquifer heterogeneities, or other complications related to borehole integrity or operator error, which could greatly exceed the inherent sources of error. However, the findings reported here have been shown to be in agreement with the previous empirical work. On this basis, properly installed and functioning PVPs should be expected to produce estimates of groundwater speed with uncertainties less than ± 15%, with the most accurate values of groundwater speed expected when horizontal flow is incident on the probe surface at about 50° from the active injection port. Directions can be measured with uncertainties less than

  8. Primary structure and promoter analysis of leghemoglobin genes of the stem-nodulated tropical legume Sesbania rostrata: conserved coding sequences, cis-elements and trans-acting factors

    DEFF Research Database (Denmark)

    Metz, B A; Welters, P; Hoffmann, H J;

    1988-01-01

    The primary structure of a leghemoglobin (lb) gene from the stem-nodulated, tropical legume Sesbania rostrata and two lb gene promoter regions was analysed. The S. rostrata lb gene structure and Lb amino acid composition were found to be highly conserved with previously described lb genes and Lb ...

  9. Spatially resolved synchrotron-induced X-ray fluorescence analyses of metal point drawings and their mysterious inscriptions

    Energy Technology Data Exchange (ETDEWEB)

    Reiche, Ina [Staatliche Museen zu Berlin (Germany)]. E-mail: ina.reiche@culture.gouv.fr; Radtke, Martin [Bundesanstalt fuer Materialforschung und-pruefung (BAM), Berlin (Germany); Berger, Achim [Bundesanstalt fuer Materialforschung und-pruefung (BAM), Berlin (Germany); Goerner, Wolf [Bundesanstalt fuer Materialforschung und-pruefung (BAM), Berlin (Germany); Ketelsen, Thomas [Staatliche Kunstsammlungen Dresden, Kupferstich-Kabinett, Dresden (Germany); Merchel, Silke [Bundesanstalt fuer Materialforschung und-pruefung (BAM), Berlin (Germany); Riederer, Josef [Staatliche Museen zu Berlin (Germany); Riesemeier, Heinrich [Bundesanstalt fuer Materialforschung und-pruefung (BAM), Berlin (Germany); Roth, Michael [Staatliche Museen zu Berlin (Germany)

    2004-10-08

    Synchrotron-induced X-ray fluorescence (Sy-XRF) analysis was used to study the chemical composition of precious Renaissance silverpoint drawings. Drawings by famous artists such as Albrecht Duerer (1471-1528) and Jan van Eyck (approximately 1395-1441) must be investigated non-destructively. Moreover, extremely sensitive synchrotron- or accelerator-based techniques are needed since only small quantities of silver are deposited on the paper. New criteria for attributing these works to a particular artist could be established based on the analysis of the chemical composition of the metal points used. We illustrate how analysis can give new art historical information by means of two case studies. Two particular drawings, one of Albrecht Duerer, showing a profile portrait of his closest friend, 'Willibald Pirckheimer' (1503), and a second one attributed to Jan van Eyck, showing a 'Portrait of an elderly man', often named 'Niccolo Albergati', are the object of intense art historical controversy. Both drawings show inscriptions next to the figures. Analyses by Sy-XRF could reveal the same kind of silverpoint for the Pirckheimer portrait and its mysterious Greek inscription, contrary to the drawing by Van Eyck where at least three different metal points were applied. Two different types of silver marks were found in this portrait. Silver containing gold marks were detected in the inscriptions and over-subscriptions. This is the first evidence of the use of gold points for metal point drawings in the Middle Ages.

  10. Identification and characterization of cis elements in the STAT3 gene regulating STAT3 alpha and STAT3 beta messenger RNA splicing.

    Science.gov (United States)

    Shao, H; Quintero, A J; Tweardy, D J

    2001-12-15

    Signal transducer and activator of transcription 3 (STAT3) is an oncogene and a critical regulator of multiple cell-fate decisions, including myeloid cell differentiation. Two isoforms of STAT3 have been identified: alpha (p92) and beta (p83). These differ structurally in their C-terminal transactivation domains, resulting in distinct functional activities. The cis genetic elements that regulate the ratio of alpha to beta messenger RNA (mRNA) are unknown. In this study, cloning, sequencing, and splicing analysis of the human and murine STAT3 genes revealed a highly conserved 5' donor site for generation of both alpha and beta mRNA and distinct branch-point sequences, polypyrimidine tracts, and 3' acceptor sites (ASs) for each. The beta 3' AS was found to be located 50 nucleotides downstream of the alpha 3' AS in exon 23. Two additional cryptic 3' ASs (delta and epsilon) were also identified. Thus, we identified for the first time the cis regulatory sequences responsible for generation of STAT3 alpha and STAT3 beta mRNA.

  11. ORA47 (octadecanoid-responsive AP2/ERF-domain transcription factor 47) regulates jasmonic acid and abscisic acid biosynthesis and signaling through binding to a novel cis-element.

    Science.gov (United States)

    Chen, Hsing-Yu; Hsieh, En-Jung; Cheng, Mei-Chun; Chen, Chien-Yu; Hwang, Shih-Ying; Lin, Tsan-Piao

    2016-07-01

    ORA47 (octadecanoid-responsive AP2/ERF-domain transcription factor 47) of Arabidopsis thaliana is an AP2/ERF domain transcription factor that regulates jasmonate (JA) biosynthesis and is induced by methyl JA treatment. The regulatory mechanism of ORA47 remains unclear. ORA47 is shown to bind to the cis-element (NC/GT)CGNCCA, which is referred to as the O-box, in the promoter of ABI2. We proposed that ORA47 acts as a connection between ABA INSENSITIVE1 (ABI1) and ABI2 and mediates an ABI1-ORA47-ABI2 positive feedback loop. PORA47:ORA47-GFP transgenic plants were used in a chromatin immunoprecipitation (ChIP) assay to show that ORA47 participates in the biosynthesis and/or signaling pathways of nine phytohormones. Specifically, many abscisic acid (ABA) and JA biosynthesis and signaling genes were direct targets of ORA47 under stress conditions. The JA content of the P35S:ORA47-GR lines was highly induced under wounding and moderately induced under water stress relative to that of the wild-type plants. The wounding treatment moderately increased ABA accumulation in the transgenic lines, whereas the water stress treatment repressed the ABA content. ORA47 is proposed to play a role in the biosynthesis of JA and ABA and in regulating the biosynthesis and/or signaling of a suite of phytohormone genes when plants are subjected to wounding and water stress. PMID:26974851

  12. Surface Observation and Pore Size Analyses of Polypropylene/Low-Melting Point Polyester Filter Materials: Influences of Heat Treatment

    Directory of Open Access Journals (Sweden)

    Lin Jia-Horng

    2016-01-01

    Full Text Available This study proposes making filter materials with polypropylene (PP and low-melting point (LPET fibers. The influences of temperatures and times of heat treatment on the morphology of thermal bonding points and average pore size of the PP/LPET filter materials. The test results indicate that the morphology of thermal bonding points is highly correlated with the average pore size. When the temperature of heat treatment is increased, the fibers are joined first with the thermal bonding points, and then with the large thermal bonding areas, thereby decreasing the average pore size of the PP/LPET filter materials. A heat treatment of 110 °C for 60 seconds can decrease the pore size from 39.6 μm to 12.0 μm.

  13. Two-electron F' centers in alkali halides: a saddle point approach. I. General and semicontinuum analyses

    OpenAIRE

    Georgiev, Mladen

    2006-01-01

    The F' center in an alkali halide forms when an anion vacancy traps two electrons which is the prerequisite of a diatomic molecule. Indeed, the center may displace left or right along in a (110) plane, due to its coupling to the B_{1u} vibrational mode of polarization respectively. On jumping from the initial position to the final position the F' center passes through a saddle point which configuration is molecule-like being conformed by two neighboring semi-vacancies along . Each semi-vaca...

  14. Analyses of point mutation repair and allelic heterogeneity generated by CRISPR/Cas9 and single-stranded DNA oligonucleotides.

    Science.gov (United States)

    Bialk, Pawel; Sansbury, Brett; Rivera-Torres, Natalia; Bloh, Kevin; Man, Dula; Kmiec, Eric B

    2016-09-09

    The repair of a point mutation can be facilitated by combined activity of a single-stranded oligonucleotide and a CRISPR/Cas9 system. While the mechanism of action of combinatorial gene editing remains to be elucidated, the regulatory circuitry of nucleotide exchange executed by oligonucleotides alone has been largely defined. The presence of the appropriate CRISPR/Cas9 system leads to an enhancement in the frequency of gene editing directed by single-stranded DNA oligonucleotides. While CRISPR/Cas9 executes double-stranded DNA cleavage efficiently, closure of the broken chromosomes is dynamic, as varying degrees of heterogeneity of the cleavage products appear to accompany the emergence of the corrected base pair. We provide a detailed analysis of allelic variance at and surrounding the target site. In one particular case, we report sequence alteration directed by a distinct member of the same gene family. Our data suggests that single-stranded DNA molecules may influence DNA junction heterogeneity created by CRISPR/Cas9.

  15. Analyses of point mutation repair and allelic heterogeneity generated by CRISPR/Cas9 and single-stranded DNA oligonucleotides.

    Science.gov (United States)

    Bialk, Pawel; Sansbury, Brett; Rivera-Torres, Natalia; Bloh, Kevin; Man, Dula; Kmiec, Eric B

    2016-01-01

    The repair of a point mutation can be facilitated by combined activity of a single-stranded oligonucleotide and a CRISPR/Cas9 system. While the mechanism of action of combinatorial gene editing remains to be elucidated, the regulatory circuitry of nucleotide exchange executed by oligonucleotides alone has been largely defined. The presence of the appropriate CRISPR/Cas9 system leads to an enhancement in the frequency of gene editing directed by single-stranded DNA oligonucleotides. While CRISPR/Cas9 executes double-stranded DNA cleavage efficiently, closure of the broken chromosomes is dynamic, as varying degrees of heterogeneity of the cleavage products appear to accompany the emergence of the corrected base pair. We provide a detailed analysis of allelic variance at and surrounding the target site. In one particular case, we report sequence alteration directed by a distinct member of the same gene family. Our data suggests that single-stranded DNA molecules may influence DNA junction heterogeneity created by CRISPR/Cas9. PMID:27609304

  16. Effects of advanced glycosylation end products on interactions between cis-elements and trans-acting factors of hepatic insulin receptor gene%晚期糖基化终末产物对胰岛素受体顺式调控元件和反式作用因子相互作用的影响

    Institute of Scientific and Technical Information of China (English)

    戎健; 于长青; 杨沛

    2009-01-01

    , along with nonspecifie binding increasing. Conclusion The impact of AGEs on hlR gene expression seems to be related to the effects on cis-elements and trans-acting factors.

  17. Prothrombin time and activated partial thromboplastin time using a point-of-care analyser (Abaxis VSpro®) in Bennett's wallabies (Macropus rufogriseus).

    Science.gov (United States)

    Nevitt, B N; Chinnadurai, S K; Watson, M K; Langan, J N; Adkesson, M J

    2016-10-01

    There are few reports of coagulation times in marsupial species. Blood samples collected from 14 Bennett's wallabies (Macropus rufogriseus) under anaesthesia during routine health assessments were analysed for prothrombin time (PT) and activated partial thromboplastin time (aPTT) using a point-of-care analyser (POC) (Abaxis VSPro®). The wallabies had an aPTT mean of 78.09 s and median of 78.1 s. The PT for all wallabies was greater than 35 s, exceeding the longest time measured on the POC. Although PT was significantly longer, aPTT was similar to the manufacturer's domestic canine reference range. PMID:27671083

  18. Influence of Immersion Conditions on The Tensile Strength of Recycled Kevlar®/Polyester/Low-Melting-Point Polyester Nonwoven Geotextiles through Applying Statistical Analyses

    Directory of Open Access Journals (Sweden)

    Jing-Chzi Hsieh

    2016-05-01

    Full Text Available The recycled Kevlar®/polyester/low-melting-point polyester (recycled Kevlar®/PET/LPET nonwoven geotextiles are immersed in neutral, strong acid, and strong alkali solutions, respectively, at different temperatures for four months. Their tensile strength is then tested according to various immersion periods at various temperatures, in order to determine their durability to chemicals. For the purpose of analyzing the possible factors that influence mechanical properties of geotextiles under diverse environmental conditions, the experimental results and statistical analyses are incorporated in this study. Therefore, influences of the content of recycled Kevlar® fibers, implementation of thermal treatment, and immersion periods on the tensile strength of recycled Kevlar®/PET/LPET nonwoven geotextiles are examined, after which their influential levels are statistically determined by performing multiple regression analyses. According to the results, the tensile strength of nonwoven geotextiles can be enhanced by adding recycled Kevlar® fibers and thermal treatment.

  19. Analysed a defective of the machine for a cap-tube nuclear fuel element ME-27 from its electricity point of view

    International Nuclear Information System (INIS)

    It has been analysed a defective of the machine for a cap-tube nuclear fuel element ME-27 from its electricity point of view. The machine uses magnetic force resistance welding technique. A short circuit was happened within the machine because the nut for tightening high voltage cable for welding transformer was broken so that the cable touched the machine body and produced the short circuit. This condition made both the primary circuit breaker in the building down and produced high voltage pulse induction to the electronic circuit within the machine so that one of its electronic components was defective. This case becomes warnings on how important of tightening a nut according to its strength specification (using wrench torque) and the necessity of voltage transient limitation circuit to be installed. Both of the warnings are necessary for any equipment consuming high electric current oriented such as the ME-27 machine. (author)

  20. Evaluating the effect of sample type on American alligator (Alligator mississippiensis) analyte values in a point-of-care blood analyser.

    Science.gov (United States)

    Hamilton, Matthew T; Finger, John W; Winzeler, Megan E; Tuberville, Tracey D

    2016-01-01

    The assessment of wildlife health has been enhanced by the ability of point-of-care (POC) blood analysers to provide biochemical analyses of non-domesticated animals in the field. However, environmental limitations (e.g. temperature, atmospheric humidity and rain) and lack of reference values may inhibit researchers from using such a device with certain wildlife species. Evaluating the use of alternative sample types, such as plasma, in a POC device may afford researchers the opportunity to delay sample analysis and the ability to use banked samples. In this study, we examined fresh whole blood, fresh plasma and frozen plasma (sample type) pH, partial pressure of carbon dioxide (PCO2), bicarbonate (HCO3 (-)), total carbon dioxide (TCO2), base excess (BE), partial pressure of oxygen (PO2), oxygen saturation (sO2) and lactate concentrations in 23 juvenile American alligators (Alligator mississippiensis) using an i-STAT CG4+ cartridge. Our results indicate that sample type had no effect on lactate concentration values (F 2,65 = 0.37, P = 0.963), suggesting that the i-STAT analyser can be used reliably to quantify lactate concentrations in fresh and frozen plasma samples. In contrast, the other seven blood parameters measured by the CG4+ cartridge were significantly affected by sample type. Lastly, we were able to collect blood samples from all alligators within 2 min of capture to establish preliminary reference ranges for juvenile alligators based on values obtained using fresh whole blood. PMID:27382469

  1. Time point-based integrative analyses of deep-transcriptome identify four signal pathways in blastemal regeneration of zebrafish lower jaw.

    Science.gov (United States)

    Zhang, Hui; Wang, Xuelong; Lyu, Kailun; Gao, Siqi; Wang, Guan; Fan, Chunxin; Zhang, Xin A; Yan, Jizhou

    2015-03-01

    There has been growing interest in applying tissue engineering to stem cell-based regeneration therapies. We have previously reported that zebrafish can faithfully regenerate complicated tissue structures through blastemal cell type conversions and tissue reorganization. To unveil the regenerative factors and engineering arts of blastemal regeneration, we conducted transcriptomal analyses at four time points corresponding to preamputation, re-epitheliation, blastemal formation, and respecification. By combining the hierarchical gene ontology term network, the DAVID annotation system, and Euclidean distance clustering, we identified four signaling pathways: foxi1-foxo1b-pou3f1, pax3a-mant3a-col11/col2, pou5f1-cdx4-kdrl, and isl1-wnt11 PCP-sox9a. Results from immunohistochemical staining and promoter-driven transgenic fish suggest that these pathways, respectively, define wound epidermis reconstitution, cell type conversions, blastemal angiogenesis/vasculogenesis, and cartilage matrix-orientation. Foxi1 morpholino-knockdown caused expansions of Foxo1b- and Pax3a-expression in the basal layer-blastemal junction region. Moreover, foxi1 morphants displayed increased sox9a and hoxa2b transcripts in the embryonic pharyngeal arches. Thus, a Foxi1 signal switch is required to establish correct tissue patterns, including re-epitheliation and blastema formation. This study provides novel insight into a blastema regeneration strategy devised by epithelial cell transdifferentiation, blood vessel engineering, and cartilage matrix deposition. PMID:25420467

  2. Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes.

    Directory of Open Access Journals (Sweden)

    Maja Bucan

    2009-06-01

    Full Text Available The genetics underlying the autism spectrum disorders (ASDs is complex and remains poorly understood. Previous work has demonstrated an important role for structural variation in a subset of cases, but has lacked the resolution necessary to move beyond detection of large regions of potential interest to identification of individual genes. To pinpoint genes likely to contribute to ASD etiology, we performed high density genotyping in 912 multiplex families from the Autism Genetics Resource Exchange (AGRE collection and contrasted results to those obtained for 1,488 healthy controls. Through prioritization of exonic deletions (eDels, exonic duplications (eDups, and whole gene duplication events (gDups, we identified more than 150 loci harboring rare variants in multiple unrelated probands, but no controls. Importantly, 27 of these were confirmed on examination of an independent replication cohort comprised of 859 cases and an additional 1,051 controls. Rare variants at known loci, including exonic deletions at NRXN1 and whole gene duplications encompassing UBE3A and several other genes in the 15q11-q13 region, were observed in the course of these analyses. Strong support was likewise observed for previously unreported genes such as BZRAP1, an adaptor molecule known to regulate synaptic transmission, with eDels or eDups observed in twelve unrelated cases but no controls (p = 2.3x10(-5. Less is known about MDGA2, likewise observed to be case-specific (p = 1.3x10(-4. But, it is notable that the encoded protein shows an unexpectedly high similarity to Contactin 4 (BLAST E-value = 3x10(-39, which has also been linked to disease. That hundreds of distinct rare variants were each seen only once further highlights complexity in the ASDs and points to the continued need for larger cohorts.

  3. TopCAT and PySESA: Open-source software tools for point cloud decimation, roughness analyses, and quantitative description of terrestrial surfaces

    Science.gov (United States)

    Hensleigh, J.; Buscombe, D.; Wheaton, J. M.; Brasington, J.; Welcker, C. W.; Anderson, K.

    2015-12-01

    The increasing use of high-resolution topography (HRT) constructed from point clouds obtained from technology such as LiDAR, SoNAR, SAR, SfM and a variety of range-imaging techniques, has created a demand for custom analytical tools and software for point cloud decimation (data thinning and gridding) and spatially explicit statistical analysis of terrestrial surfaces. We will present on a number of analytical and computational tools designed to quantify surface roughness and texture, directly from point clouds in a variety of ways (using spatial- and frequency-domain statistics). TopCAT (Topographic Point Cloud Analysis Toolkit; Brasington et al., 2012) and PySESA (Python program for Spatially Explicit Spectral Analysis) both work by applying a small moving window to (x,y,z) data to calculate a suite of (spatial and spectral domain) statistics, which are then spatially-referenced on a regular (x,y) grid at a user-defined resolution. Collectively, these tools facilitate quantitative description of surfaces and may allow, for example, fully automated texture characterization and segmentation, roughness and grain size calculation, and feature detection and classification, on very large point clouds with great computational efficiency. Using tools such as these, it may be possible to detect geomorphic change in surfaces which have undergone minimal elevation difference, for example deflation surfaces which have coarsened but undergone no net elevation change, or surfaces which have eroded and accreted, leaving behind a different textural surface expression than before. The functionalities of the two toolboxes are illustrated with example high-resolution bathymetric point cloud data collected with multibeam echosounder, and topographic data collected with LiDAR.

  4. Atomistic analyses of competition between site-selective segregation and association of point defects at grain boundary in Y2O3-doped ZrO2

    International Nuclear Information System (INIS)

    The site-selective occupation of point defects, Y3+ ions (Y′Zr) and O2- vacancies (VÖ), and their associations at a symmetric tilt grain boundary (GB) are studied to understand their competitive contribution to energetically favorable atomic arrangements by using atomistic simulations. It is found that at the GB there are the favorable sites for segregation of an isolated Y′Zr and VÖ. This indicates that the driving force for the site-selective segregation is present. Moreover, our results of Y′Zr-VÖ association at the GB show that the lattice energies are very dispersed despite that a second-nearest neighbor (SNN) vacancy to Y′Zr is favored for bulk Y2O3-doped ZrO2. The result suggests that the site-selective segregation has significant effects on the favorable point defect arrangement at the GB core, competing with the point defect associations. For more realistic cases, Monte Carlo simulations are performed to reveal favorable atomic arrangements for a high dopant concentration, where point defects are crowded at the GB. The results show that the region of GB segregation can be classified with respect to O2- coordination to cation species; at the GB core the favorable configuration is not necessarily a SNN O2- vacancy relative to Y3+. On the other hand, eight-fold O2- coordination is sustained for Y3+ ions more than ∼3 Å distant from the GB plane. The difference in O2- coordination may play an important role in O2- ionic conductivity at GBs via the energetics for O2- migration. (author)

  5. Projecting the Current & Future Impact of Storm Surges on Coastal Flood Extent at Pigeon Point, South-West Tobago, through Hydrodynamic Modelling Analyses

    Science.gov (United States)

    Seenath, Avidesh; Wilson, Matthew; Miller, Keith

    2014-05-01

    Under climate change, sea levels will continue to rise and the intensity of tropical storms and hurricanes will amplify. Consequently, the incidence rate of high magnitude storm surges may increase which will enhance the probability of coastal flood events in low lying coastal communities. The purpose of this study is to determine the current and potential future areas that may be at risk of flooding from storm surges, of different magnitudes, for the low lying Pigeon Point area of south-west Tobago. The objective of this research is to develop an understanding of the extent of flooding that these events can ensue on low lying coastal areas that are widespread through the Caribbean under current and future sea level conditions. A two-dimensional hydrodynamic flood model was created for Pigeon Point using the model code LISFLOOD-FP by incorporating topographic data of the terrain and sea bed referenced to mean sea level together with tides. This was used to assess the impact of different storm surge levels on the study area. Storm surge scenarios were computed using information acquired from the Saffir-Simpson hurricane scale which provides an estimate of storm surge height based on the category of hurricane, existing projections of global sea level rise and recorded values of high tide for Pigeon Point. Results indicate that the quantity of area likely to flood, in each surge scenario, increases significantly under future projected global sea level conditions compared to current conditions. The potential implications of this on the local population, island's economy and beach geomorphology are examined. Results obtained were incorporated into a Geographic Information System (GIS) to produce current and future flood maps indicating potential inundation extent based on storm surge height to guide coastal flood management programmes in south-west Tobago. We conclude that greater focus should be placed on implementing flood mitigation measures to protect our coasts and

  6. Semi-quantitative and simulation analyses of effects of {gamma} rays on determination of calibration factors of PET scanners with point-like {sup 22}Na sources

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, Tomoyuki [School of Allied Health Sciences, Kitasato University, 1-15-1, Kitasato, Minamiku, Sagamihara, Kanagawa, 252-0373 (Japan); Sato, Yasushi [National Institute of Advanced Industrial Science and Technology, 1-1-1, Umezono, Tsukuba, Ibaraki, 305-8568 (Japan); Oda, Keiichi [Tokyo Metropolitan Institute of Gerontology, 1-1, Nakamachi, Itabashi, Tokyo, 173-0022 (Japan); Wada, Yasuhiro [RIKEN Center for Molecular Imaging Science, 6-7-3, Minamimachi, Minatoshima, Chuo, Kobe, Hyogo, 650-0047 (Japan); Murayama, Hideo [National Institute of Radiological Sciences, 4-9-1, Anagawa, Inage, Chiba, 263-8555 (Japan); Yamada, Takahiro, E-mail: hasegawa@kitasato-u.ac.jp [Japan Radioisotope Association, 2-28-45, Komagome, Bunkyo-ku, Tokyo, 113-8941 (Japan)

    2011-09-21

    The uncertainty of radioactivity concentrations measured with positron emission tomography (PET) scanners ultimately depends on the uncertainty of the calibration factors. A new practical calibration scheme using point-like {sup 22}Na radioactive sources has been developed. The purpose of this study is to theoretically investigate the effects of the associated 1.275 MeV {gamma} rays on the calibration factors. The physical processes affecting the coincidence data were categorized in order to derive approximate semi-quantitative formulae. Assuming the design parameters of some typical commercial PET scanners, the effects of the {gamma} rays as relative deviations in the calibration factors were evaluated by semi-quantitative formulae and a Monte Carlo simulation. The relative deviations in the calibration factors were less than 4%, depending on the details of the PET scanners. The event losses due to rejecting multiple coincidence events of scattered {gamma} rays had the strongest effect. The results from the semi-quantitative formulae and the Monte Carlo simulation were consistent and were useful in understanding the underlying mechanisms. The deviations are considered small enough to correct on the basis of precise Monte Carlo simulation. This study thus offers an important theoretical basis for the validity of the calibration method using point-like {sup 22}Na radioactive sources.

  7. Analysing the Information Content of Point Measurements of the Soil Hydraulic State Variables by Global Sensitivity Analysis and Multiobjective Parameter Estimation

    Science.gov (United States)

    Werisch, Stefan; Lennartz, Franz; Schütze, Niels

    2015-04-01

    Inverse modeling has become a common approach to infer the parameters of the water retention and hydraulic conductivity functions from observations of the vadose zone state variables during dynamic experiments under varying boundary conditions. This study focuses on the estimation and investigation of the feasibility of effective soil hydraulic properties to describe the soil water flow in an undisturbed 1m³ lysimeter. The lysimeter is equipped with 6 one-dimensional observation arrays consisting of 4 tensiometers and 4 water content probes each, leading to 6 replicated one-dimensional observations which establish the calibration data base. Methods of global sensitivity analysis and multiobjective calibration strategies have been applied to examine the information content about the soil hydraulic parameters of the Mualem-van Genuchten (MvG) model contained in the individual data sets, to assess the tradeoffs between the different calibration data sets and to infer effective soil hydraulic properties for each of the arrays. The results show that (1) information about the MvG model parameters decreases with increasing depth, due to effects of overlapping soil layers and reduced soil water dynamics, (2) parameter uncertainty is affected by correlation between the individual parameters. Despite these difficulties, (3) effective one-dimensional parameter sets, which produce satisfying fits and have acceptable trade-offs, can be identified for all arrays, but (4) the array specific parameter sets vary significantly and cannot be transferred to simulate the water flow in other arrays, and (5) none of the parameter sets is suitable to simulate the integral water flow within the lysimeter. The results of the study challenge the feasibility of the inversely estimated soil hydraulic properties from multiple point measurements of the soil hydraulic state variables. Relying only on point measurements inverse modeling can lead to promising results regarding the observations

  8. Analysing the Information Content of Point Measurements of the Vadose Zone State Variables for the Inverse Estimation of Soil Hydraulic Parameters

    Science.gov (United States)

    Werisch, S.; Lennartz, F.

    2014-12-01

    Inverse modeling has become a common approach to infer the parameters of the water retention and hydraulic conductivity functions from observations of the vadose zone state variables during dynamic experiments under varying boundary conditions. This study focuses on the estimation and investigation of the feasibility of effective soil hydraulic properties to describe the soil water flow in an undisturbed 1m³ lysimeter. The lysimeter is equipped with 6 one-dimensional observation arrays consisting of 4 tensiometers and 4 water content probes each, leading to 6 replicated one-dimensional observations which establish the calibration data base. Methods of global sensitivity analysis and multiobjective calibration strategies have been applied to examine the information content about the soil hydraulic parameters of the Mualem-van Genuchten (MvG) model contained in the individual data sets, to assess the tradeoffs between the different calibration data sets and to infer effective soil hydraulic properties for each of the arrays. The results show that (1) information about the MvG model parameters decreases with increasing depth, due to effects of overlapping soil layers and reduced soil water dynamics, (2) parameter uncertainty is affected by correlation between the individual parameters. Despite these difficulties, (3) effective one-dimensional parameter sets, which produce satisfying fits and have acceptable trade-offs, can be identified for all arrays, but (4) the array specific parameter sets vary significantly and cannot be transferred to simulate the water flow in other arrays, and (5) none of the parameter sets is suitable to simulate the integral water flow within the lysimeter. The results of the study challenge the feasibility of the inversely estimated soil hydraulic properties from multiple point measurements of the soil hydraulic state variables. Relying only on point measurements of the state variables, which is the usual case, inverse modeling can lead to

  9. Onset of slugging criterion based on singular points and stability analyses of transient one-dimensional two-phase flow equations of two-fluid model

    International Nuclear Information System (INIS)

    A two-step approach has been used to obtain a new criterion for the onset of slug formation : (1) In the first step, a more general expression than the existing models for the onset of slug flow criterion has been derived from the analysis of singular points and neutral stability conditions of the transient one-dimensional two-phase flow equations of two-fluid model. (2) In the second step, introducing simplifications and incorporating a parameter into the general expression obtained in the first step to satisfy a number of physical conditions a priori specified, a new simple criterion for the onset of slug flow has been derived. Comparisons of the present model with existing models and experimental data show that the present model agree very closely with Taitel and Dukler's model and experimental data in horizontal pipes. In an inclined pipe (θ=50 deg ), however, the difference between the predictions of the present model and those of existing models is appreciably large and the present model gives the best agreement with Ohnuki et al.'s data. 17 refs., 5 figs., 1 tab. (author)

  10. Two Different Protocols for Knee Joint Motion Analyses in the Stance Phase of Gait: Correlation of the Rigid Marker Set and the Point Cluster Technique

    Directory of Open Access Journals (Sweden)

    Takashi Fukaya

    2012-01-01

    Full Text Available Objective. There are no reports comparing the protocols provided by rigid marker set (RMS and point cluster technique (PCT, which are similar in terms of estimating anatomical landmarks based on markers attached to a segment. The purpose of this study was to clarify the correlation of the two different protocols, which are protocols for knee motion in gait, and identify whether measurement errors arose at particular periods during the stance phase. Methods. The study subjects were 10 healthy adults. All estimated anatomical landmarks were which their positions, calculated by each protocol of the PCT and RMS, were compared using Pearson’s product correlation coefficients. To examine the reliability of the angle changes of the knee joint measured by RMS and the PCT, the coefficient of multiple correlations (CMCs was used. Results. Although the estimates of the anatomical landmarks showed high correlations of >0.90 (<0.01 for the Y- and Z-coordinates, the correlations were low for the X-coordinates at all anatomical landmarks. The CMC was 0.94 for flexion/extension, 0.74 for abduction/adduction, and 0.71 for external/internal rotation. Conclusion. Flexion/extension and abduction/adduction of the knee by two different protocols had comparatively little error and good reliability after 30% of the stance phase.

  11. 拟南芥bZIP1转录因子通过与ABRE元件结合调节ABA信号传导%Arabidopisis bZIP1 Transcription Factor Binding to the ABRE Cis-Element Regulates Abscisic Acid Signal Transduction

    Institute of Scientific and Technical Information of China (English)

    孙晓丽; 李勇; 才华; 柏锡; 纪巍; 季佐军; 朱延明

    2011-01-01

    Abscisic acid (ABA) is a phytohormone and mediates the response and adaptation of higher plants to various environmental stresses during vegetative growth.The basic leucine zipper (bZIP) transcription factors are also important regulators of plant development and abiotic resistance, acting through either ABA-dependent or ABA-independent pathways.In this study, we investigated and characterized the involvement of the AtbZIP1 gene in plant responsiveness to ABA.As confirmed by PCR and RT-PCR, AtbZIP1 has been silenced in mutant Arabidopsis ko-1 (SALK_059343) and ko-2 (SALK_069489C).The AtbZIP1 knockout plants demonstrated reduced sensitivity to ABA both at the seed germination and seedling stage with improvements in rates of germination, leaf opening/greening, and primary root length.In order to investigate whether the regulation of AtbZIP1-mediated ABA responsiveness depended on the ABA-responsive elements (ABRE), we expressed the AtbZIP1 HIS6 fusion protein in E.coli and found that the AtbZIP1 HIS6 specifically bound to the ABRE cis-elements.Semi-quantitive RT PCR showed that AtbZIP1 disruption altered expressions of some ABA responsive genes, such as NCED3, RD22, KIN1, and RD29A.Our results indicated that AtbZIP1 regulates abscisic acid signal transduction by binding to the ABREs and altered the expressions of the ABA responsive genes.%ABA作为一种重要的植物激素和生长凋节剂,介导了高等植物在营养生长阶段对各种外界环境的响应和适应.bZIP类转录因子可以通过ABA依赖途径和ABA非依赖途径调节植物的生长发育和对非生物胁迫的耐性.本研究通过AtbZIP1 T-DNA插入突变的拟南芥植株ko-1(SALK_059343)和ko-2(SALK_069489C)在ABA处理后的表型实验,验证了AtbZIP1参与ABA依赖的信号传导通路.采用"三引物法",分别在DNA水平和RNA水平通过PCR和RT-PCR验证了AtbZIP1基因在拟南芥突变体中的沉默效果.定量分析数据表明,在种子萌发阶段,经过0.6μmolL-1

  12. Analyse numérique du problème de déplacement du noyau fondu en soudage par points de tôles à différentes épaisseurs

    Science.gov (United States)

    Benkedda, Y.; Tahar Chaouch, K.; Ibrir, B.

    2005-05-01

    Le soudage par résistance par points est une technique d'assemblage très répandue, en particulier dans l'industrie automobile, parce qu'elle est rapide, fiable et bon marché. Pour cela, la réalisation d'un point de soudure de qualité reste encore une préoccupation de l'industrie, surtout lorsqu'il s'agit de souder des tôles à différentes épaisseurs. Les premiers modèles mathématiques et expérimentaux qui couvrent ces différents aspects, sont principalement dirigés vers les modèles de transfert de chaleur ou vers les phénomènes de surfaces (modèles de surfaces) ; ces derniers, sont un problème d'importance, puisqu'ils interviennent chaque fois qu'un transfert de chaleur s'effectue entre deux solides accolés. Les physiciens ont étudie expérimentalement la réponse de la région de contact de deux solides aux pulsations de courant. Ils ont montré que le contact possède une résistance de resserrement due aux aspérités de surface, et que la température moyenne à l'interface des deux solides sous un chargement uniforme produit un adoucissement local lequel fait augmenter la région de contact. Le but de ce travail est consacré à l'analyse de l'influence des épaisseurs de tôles sur la position du noyau fondu. Expérimentalement, il a été montré que lorsque le rapport des épaisseurs est compris entre 1/1 et 1/10, le noyau fondu se déplace vers la pièce la plus épaisse. Ce phénomène peut s'expliquer à partir d'une étude thermique. Nous proposons donc, de résoudre le problème de transfert thermique transitoire associé au processus de soudage par points moyennant une méthode numérique. Ce modèle est capable de prédire l'évolution du noyau fondu en fonction des paramètres du procédé à savoir l'intensité de soudage et temps de soudage, ainsi que la répartition thermique en chaque point de l'assemblage.

  13. Massive Collection of Full-Length Complementary DNA Clones and Microarray Analyses:. Keys to Rice Transcriptome Analysis

    Science.gov (United States)

    Kikuchi, Shoshi

    2009-02-01

    Completion of the high-precision genome sequence analysis of rice led to the collection of about 35,000 full-length cDNA clones and the determination of their complete sequences. Mapping of these full-length cDNA sequences has given us information on (1) the number of genes expressed in the rice genome; (2) the start and end positions and exon-intron structures of rice genes; (3) alternative transcripts; (4) possible encoded proteins; (5) non-protein-coding (np) RNAs; (6) the density of gene localization on the chromosome; (7) setting the parameters of gene prediction programs; and (8) the construction of a microarray system that monitors global gene expression. Manual curation for rice gene annotation by using mapping information on full-length cDNA and EST assemblies has revealed about 32,000 expressed genes in the rice genome. Analysis of major gene families, such as those encoding membrane transport proteins (pumps, ion channels, and secondary transporters), along with the evolution from bacteria to higher animals and plants, reveals how gene numbers have increased through adaptation to circumstances. Family-based gene annotation also gives us a new way of comparing organisms. Massive amounts of data on gene expression under many kinds of physiological conditions are being accumulated in rice oligoarrays (22K and 44K) based on full-length cDNA sequences. Cluster analyses of genes that have the same promoter cis-elements, that have similar expression profiles, or that encode enzymes in the same metabolic pathways or signal transduction cascades give us clues to understanding the networks of gene expression in rice. As a tool for that purpose, we recently developed "RiCES", a tool for searching for cis-elements in the promoter regions of clustered genes.

  14. Tipping Point

    Medline Plus

    Full Text Available ... en español Blog About OnSafety CPSC Stands for Safety The Tipping Point Home > 60 Seconds of Safety (Videos) > The Tipping Point The Tipping Point by ... danger death electrical fall furniture head injury product safety television tipover tv Watch the video in Adobe ...

  15. 安徽省化肥面源污染环境风险分析%Environmental Risk Analyses of Non-Point Source Pollution From Fertilization in Anhui Province, China

    Institute of Scientific and Technical Information of China (English)

    刘钦普

    2015-01-01

    Anhui, being one of the major agricultural provinces in China, is faced with a series of environmental problems, of which non-point source pollution from chemical fertilizationin farmlands is one. In order to better understand the potential threats of fertilization to the rural ecosystem and agricultural sustainable development in Anhui Province, Chi-na, environmental risk assessment ( ERA ) of fertilization was conducted. An index model for environmental risk assessment of non-point source pollution from fertilization was established and spatio-temporal variation of fertilization and environmental risk of non-point source pollution from fertilization in Anhui was analyzed. Results show that in Anhui of 2013, the total chemical fertilization intensity was 853. 6 kg·hm-2 on average; the environmental risk index of the non-point source pollution from chemical fertilization was 0. 72; the total environmental pollution risk ranked moderate; N :P : K in fertilization was 1 : 0. 52 : 0. 49;the environmental risk index of N, P and K single-element fertilizers was 0. 72, 0. 78 and 0. 65, respectively;the environmental risk of the three kinds of single-element fertilizers ranked moderate, seri-ous and light, respectively;and their spatio-temporal distribution displayed an obvious aggregation effect. In the 16 prefec-ture-leveled cities, the problem of excessive fertilizationin farmlands existed universally. Though varying sharply from region to region in severity, it displayed a specific pattern of distribution. Environmental risk was very serious in Huainan, serious in Bengbu, Lu′an, Wuhu and Tongling, and moderate in the rest of the cities.%为了深入了解化肥施用对农村生态环境的威胁,在综合考虑化肥施用强度、效率、生态安全标准、环境效应权数及作物复种指数等多种因素的基础上,构建了化肥面源污染环境风险评价指数模型,对安徽省化肥施用时空分异与面源污染环境风险进行研究.

  16. Publication point indicators

    DEFF Research Database (Denmark)

    Elleby, Anita; Ingwersen, Peter

    2010-01-01

    The paper presents comparative analyses of two publication point systems, The Norwegian and the in-house system from the interdisciplinary Danish Institute of International Studies (DIIS), used as case in the study for publications published 2006, and compares central citation-based indicators wi...

  17. Isolating the Role of Bevacizumab in Elderly Patients With Previously Untreated Nonsquamous Non–Small Cell Lung Cancer: Secondary Analyses of the ECOG 4599 and PointBreak Trials

    Science.gov (United States)

    Langer, Corey J.; Socinski, Mark A.; Patel, Jyoti D.; Sandler, Alan B.; Schiller, Joan H.; Leon, Larry; Hazard, Sebastien J.; Ramalingam, Suresh S.

    2016-01-01

    Background Patient-level data from 2 phase III studies in patients with previously untreated, advanced-stage, nonsquamous non–small cell lung cancer (NSCLC) were pooled to examine outcomes with bevacizumab and chemotherapy based on age. Methods Data from patients randomized to paclitaxel–carboplatin (PC) + bevacizumab in the Eastern Cooperative Oncology Group 4599 (E4599) and PointBreak studies were pooled and compared with E4599 patients randomized to PC alone. Patients were grouped by age: AEs) were assessed by age group in each study. Results The PC + bevacizumab and PC arms comprised 901 and 444 patients, respectively. PC + bevacizumab was associated with significant increases in overall survival relative to PC in patients AEs was reported with PC + bevacizumab vs. PC in patients <75 (63% vs. 48%; P <0.05) and ≥75 years (81% vs. 56%; P <0.05) in E4599. Conclusions This analysis demonstrates that the survival benefits associated with PC + bevacizumab extend to patient subgroups <75 years with advanced-stage NSCLC; no benefit, however, was observed for bevacizumab-eligible patients who were ≥75 years. PMID:25628268

  18. Turning Point

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Moves from the United States and North Korea give new impetus to nuclear disablement and U.S.-North Korea ties The tense situation surrounding denu-clearization on the Korean Peninsula has reached a turning point. On

  19. Human Papillomavirus Type 18 cis-Elements Crucial for Segregation and Latency.

    Science.gov (United States)

    Ustav, Mart; Castaneda, Fernando Rodriguez; Reinson, Tormi; Männik, Andres; Ustav, Mart

    2015-01-01

    Stable maintenance replication is characteristic of the latency phase of HPV infection, during which the viral genomes are actively maintained as extrachromosomal genetic elements in infected proliferating basal keratinocytes. Active replication in the S-phase and segregation of the genome into daughter cells in mitosis are required for stable maintenance replication. Most of our knowledge about papillomavirus genome segregation has come from studies of bovine papillomavirus type 1 (BPV-1), which have demonstrated that the E2 protein cooperates with cellular trans-factors and that E2 binding sites act as cis-regulatory elements in the viral genome that are essential for the segregation process. However, the genomic organization of the regulatory region in HPVs, and the properties of the viral proteins are different from those of their BPV-1 counterparts. We have designed a segregation assay for HPV-18 and used it to demonstrate that the E2 protein performs segregation in combination with at least two E2 binding sites. The cooperative binding of the E2 protein to two E2 binding sites is a major determinant of HPV-18 genome segregation, as demonstrated by the change in spacing between adjacent binding sites #1 and #2 in the HPV-18 Upstream Regulatory Region (URR). Duplication or triplication of the natural 4 bp 5'-CGGG-3' spacer between the E2 binding sites increased the cooperative binding of the E2 molecules as well as E2-dependent segregation. Removal of any spacing between these sites eliminated cooperative binding of the E2 protein and disabled segregation of the URR and HPV-18 genome. Transfer of these configurations of the E2 binding sites into viral genomes confirmed the role of the E2 protein and binding sites #1 and #2 in the segregation process. Additional analysis demonstrated that these sites also play an important role in the transcriptional regulation of viral gene expression from different HPV-18 promoters. PMID:26288015

  20. Comparative genome sequencing of drosophila pseudoobscura: Chromosomal, gene and cis-element evolution

    Energy Technology Data Exchange (ETDEWEB)

    Richards, Stephen; Liu, Yue; Bettencourt, Brian R.; Hradecky, Pavel; Letovsky, Stan; Nielsen, Rasmus; Thornton, Kevin; Todd, Melissa J.; Chen, Rui; Meisel, Richard P.; Couronne, Olivier; Hua, Sujun; Smith, Mark A.; Bussemaker, Harmen J.; van Batenburg, Marinus F.; Howells, Sally L.; Scherer, Steven E.; Sodergren, Erica; Matthews, Beverly B.; Crosby, Madeline A.; Schroeder, Andrew J.; Ortiz-Barrientos, Daniel; Rives, Catherine M.; Metzker, Michael L.; Muzny, Donna M.; Scott, Graham; Steffen, David; Wheeler, David A.; Worley, Kim C.; Havlak, Paul; Durbin, K. James; Egan, Amy; Gill, Rachel; Hume, Jennifer; Morgan, Margaret B.; Miner, George; Hamilton, Cerissa; Huang, Yanmei; Waldron, Lenee; Verduzco, Daniel; Blankenburg, Kerstin P.; Dubchak, Inna; Noor, Mohamed A.F.; Anderson, Wyatt; White, Kevin P.; Clark, Andrew G.; Schaeffer, Stephen W.; Gelbart, William; Weinstock, George M.; Gibbs, Richard A.

    2004-04-01

    The genome sequence of a second fruit fly, D. pseudoobscura, presents an opportunity for comparative analysis of a primary model organism D. melanogaster. The vast majority of Drosophila genes have remained on the same arm, but within each arm gene order has been extensively reshuffled leading to the identification of approximately 1300 syntenic blocks. A repetitive sequence is found in the D. pseudoobscura genome at many junctions between adjacent syntenic blocks. Analysis of this novel repetitive element family suggests that recombination between offset elements may have given rise to many paracentric inversions, thereby contributing to the shuffling of gene order in the D. pseudoobscura lineage. Based on sequence similarity and synteny, 10,516 putative orthologs have been identified as a core gene set conserved over 35 My since divergence. Genes expressed in the testes had higher amino acid sequence divergence than the genome wide average consistent with the rapid evolution of sex-specific proteins. Cis-regulatory sequences are more conserved than control sequences between the species but the difference is slight, suggesting that the evolution of cis-regulatory elements is flexible. Overall, a picture of repeat mediated chromosomal rearrangement, and high co-adaptation of both male genes and cis-regulatory sequences emerges as important themes of genome divergence between these species of Drosophila.

  1. Structural Analysis and Identification of Cis-Elements of Rice osRACD Gene

    Institute of Scientific and Technical Information of China (English)

    Yun-Zhe XU; Rui-Lin YOU; Nai-Hu WU

    2004-01-01

    The osRACD gene correlated with fertility transformation in the photoperiod sensitive genic male sterile rice(PGMR),Nongken 58S,encoded a rice(Oryza sativa L.ssp.japonica)small GTPase belonging to the Rac/Rho family.Inverse PCR was performed to amplify a fragment about 1.4 kb in 5′ upstream region of the osRACD promoter.Deletion mutation and gel mobility shift assay characterized two fragments(-799 to -686 nt,and -686 to -431 nt)in the osRACD promoter that could be involved in its transcriptional regulation.When these two deletion fragments were used as probe respectively,a retarded band appeared in the nuclear extracts of fertile 58S rice under short day(58S-SD).Whereas no retarded band was shown in the nuclear extracts of sterile 58S rice under long day(58S-LD).Competition assay indicated that the factors in the retarded bands binding to these two fragments were the same trans-acting factor(termed rice factor,RF).The binding affinity of RF was affected by phosphorylation and was higher in SD-growth rice than that of LD-growth rice.

  2. Human Papillomavirus Type 18 cis-Elements Crucial for Segregation and Latency.

    Directory of Open Access Journals (Sweden)

    Mart Ustav

    Full Text Available Stable maintenance replication is characteristic of the latency phase of HPV infection, during which the viral genomes are actively maintained as extrachromosomal genetic elements in infected proliferating basal keratinocytes. Active replication in the S-phase and segregation of the genome into daughter cells in mitosis are required for stable maintenance replication. Most of our knowledge about papillomavirus genome segregation has come from studies of bovine papillomavirus type 1 (BPV-1, which have demonstrated that the E2 protein cooperates with cellular trans-factors and that E2 binding sites act as cis-regulatory elements in the viral genome that are essential for the segregation process. However, the genomic organization of the regulatory region in HPVs, and the properties of the viral proteins are different from those of their BPV-1 counterparts. We have designed a segregation assay for HPV-18 and used it to demonstrate that the E2 protein performs segregation in combination with at least two E2 binding sites. The cooperative binding of the E2 protein to two E2 binding sites is a major determinant of HPV-18 genome segregation, as demonstrated by the change in spacing between adjacent binding sites #1 and #2 in the HPV-18 Upstream Regulatory Region (URR. Duplication or triplication of the natural 4 bp 5'-CGGG-3' spacer between the E2 binding sites increased the cooperative binding of the E2 molecules as well as E2-dependent segregation. Removal of any spacing between these sites eliminated cooperative binding of the E2 protein and disabled segregation of the URR and HPV-18 genome. Transfer of these configurations of the E2 binding sites into viral genomes confirmed the role of the E2 protein and binding sites #1 and #2 in the segregation process. Additional analysis demonstrated that these sites also play an important role in the transcriptional regulation of viral gene expression from different HPV-18 promoters.

  3. Point pattern analyses on typical secondary forest communities in the mountainous region of southern Jiangsu Province%苏南丘陵山区典型次生森林群落的点格局分析

    Institute of Scientific and Technical Information of China (English)

    薛岑; 刘茂松; 康昕; 郑阿宝; 侯嫦英; 关庆伟; 徐驰

    2016-01-01

    To explore spatial structure of secondary forest communities at different succession series in the hilly area of northern subtropical China, we set up 36 sampling plots in the Lishui Foresty Farm, Jiangsu Province, and conducted detailed field investigations on the woody plants in these plots. We distinguished four typical community types using ca⁃nonical correlation analysis ( CCA) across our study plots, and then used point pattern analysis to characterize the spatial distribution patterns of the main tree species for these community types. Our results suggested that in the study ar⁃ea typical forest communities were represented as Pinus massoniana-Quercus acutissima community, Ilex chinensis-P. massoniana community, Q. acutissima - Q. variabilis community and Cunninghamia lanceolata - Vernicia fordii community. Soil conditions appeared to be the primary factor resulting in the difference of community composition. Most dominant tree species in the study communities showed uniform patterns on the scale of >3 m, suggesting that intraspe⁃cific competition underlies such pattern formation. Interspecific spatial association often manifested neutral patterns, ex⁃cept for those species such as Q. acutissima and Q. variabilis, which presented significant negative correlations. Interspe⁃cific competition due to similar functional traits of these tree species was a likely driving mechanism of such association. Our study could provide a useful reference to effective management of secondary forests in northern subtropical China.%为研究北亚热带丘陵山区次生森林在不同演替序列中群落的空间结构特征,对江苏省南京市溧水林场区域内36块30 m×30 m样地中的木本植物分布进行了详细调查。在利用典范相关分析(CCA)确定不同演替阶段典型群落类型的基础上,运用点格局分析方法对各类型群落中优势树种的空间分布格局进行研究。结果表明:研究区典型森林群落

  4. Publication point indicators

    DEFF Research Database (Denmark)

    Elleby, Anita; Ingwersen, Peter

    2010-01-01

    The paper presents comparative analyses of two publication point systems, The Norwegian and the in-house system from the interdiscplinary Danish Institute for International Studies (DIIS), used as case in the study for publications published 2006, and compares central citation-based indicators...... with novel publication point indicators (PPIs) that are formalized and exemplified. Two diachronic citation windows are applied: 2006-07 and 2006-08. Web of Science (WoS) as well as Google Scholar (GS) are applied to observe the cite delay and citedness for the different document types published by DIIS......, journal articles, book chapters/conference papers and monographs. Journal Crown Indicator (JCI) calculations was based on WoS. Three PPIs are proposed: thePublication Point Ratio (PPR), which measures the sum of obtained publiacation points over the sum of the ideal pointws for the same set of documents...

  5. Immunohistochemical analyses point to epidermal origin of human Merkel cells.

    Science.gov (United States)

    Tilling, Thomas; Wladykowski, Ewa; Failla, Antonio Virgilio; Houdek, Pia; Brandner, Johanna M; Moll, Ingrid

    2014-04-01

    Merkel cells, the neurosecretory cells of skin, are essential for light-touch responses and may probably fulfill additional functions. Whether these cells derive from an epidermal or a neural lineage has been a matter of dispute for a long time. In mice, recent studies have clearly demonstrated an epidermal origin of Merkel cells. Given the differences in Merkel cell distribution between human and murine skin, it is, however, unclear whether the same holds true for human Merkel cells. We therefore attempted to gain insight into the human Merkel cell lineage by co-immunodetection of the Merkel cell marker protein cytokeratin 20 (CK20) with various proteins known to be expressed either in epidermal or in neural stem cells of the skin. Neither Sox10 nor Pax3, both established markers of the neural crest lineage, exhibited any cell co-labeling with CK20. By contrast, β1 integrin, known to be enriched in epidermal stem cells, was found in nearly 70 % of interfollicular epidermal and 25 % of follicular Merkel cells. Moreover, LRIG1, also enriched in epidermal stem cells, displayed significant co-immunolabeling with CK20 as well (approximately 20 % in the interfollicular epidermis and 7 % in the hair follicle, respectively). Further epidermal markers were detected in sporadic Merkel cells. Cells co-expressing CK20 with epidermal markers may represent a transitory state between stem cells and differentiated cells. β1 integrin is probably also synthesized by a large subset of mature Merkel cells. Summarizing, our data suggest that human Merkel cells may originate from epidermal rather than neural progenitors.

  6. Network class superposition analyses.

    Science.gov (United States)

    Pearson, Carl A B; Zeng, Chen; Simha, Rahul

    2013-01-01

    Networks are often used to understand a whole system by modeling the interactions among its pieces. Examples include biomolecules in a cell interacting to provide some primary function, or species in an environment forming a stable community. However, these interactions are often unknown; instead, the pieces' dynamic states are known, and network structure must be inferred. Because observed function may be explained by many different networks (e.g., ≈ 10(30) for the yeast cell cycle process), considering dynamics beyond this primary function means picking a single network or suitable sample: measuring over all networks exhibiting the primary function is computationally infeasible. We circumvent that obstacle by calculating the network class ensemble. We represent the ensemble by a stochastic matrix T, which is a transition-by-transition superposition of the system dynamics for each member of the class. We present concrete results for T derived from boolean time series dynamics on networks obeying the Strong Inhibition rule, by applying T to several traditional questions about network dynamics. We show that the distribution of the number of point attractors can be accurately estimated with T. We show how to generate Derrida plots based on T. We show that T-based Shannon entropy outperforms other methods at selecting experiments to further narrow the network structure. We also outline an experimental test of predictions based on T. We motivate all of these results in terms of a popular molecular biology boolean network model for the yeast cell cycle, but the methods and analyses we introduce are general. We conclude with open questions for T, for example, application to other models, computational considerations when scaling up to larger systems, and other potential analyses. PMID:23565141

  7. Identification, duplication, evolution and expression analyses of caleosins in Brassica plants and Arabidopsis subspecies.

    Science.gov (United States)

    Shen, Yue; Liu, Mingzhe; Wang, Lili; Li, Zhuowei; Taylor, David C; Li, Zhixi; Zhang, Meng

    2016-04-01

    Caleosins are a class of Ca(2+) binding proteins that appear to be ubiquitous in plants. Some of the main proteins embedded in the lipid monolayer of lipid droplets, caleosins, play critical roles in the degradation of storage lipids during germination and in lipid trafficking. Some of them have been shown to have histidine-dependent peroxygenase activity, which is believed to participate in stress responses in Arabidopsis. In the model plant Arabidopsis thaliana, caleosins have been examined extensively. However, little is known on a genome-wide scale about these proteins in other members of the Brassicaceae. In this study, 51 caleosins in Brassica plants and Arabidopsis lyrata were investigated and analyzed in silico. Among them, 31 caleosins, including 7 in A. lyrata, 11 in Brassica oleracea and 13 in Brassica napus, are herein identified for the first time. Segmental duplication was the main form of gene expansion. Alignment, motif and phylogenetic analyses showed that Brassica caleosins belong to either the H-family or the L-family with different motif structures and physicochemical properties. Our findings strongly suggest that L-caleosins are evolved from H-caleosins. Predicted phosphorylation sites were differentially conserved in H-caleosin and L-caleosins, respectively. 'RY-repeat' elements and phytohormone-related cis-elements were identified in different caleosins, which suggest diverse physiological functions. Gene structure analysis indicated that most caleosins (38 out of 44) contained six exons and five introns and their intron phases were highly conserved. Structurally integrated caleosins, such as BrCLO3-3 and BrCLO4-2, showed high expression levels and may have important roles. Some caleosins, such as BrCLO2 and BoCLO8-2, lost motifs of the calcium binding domain, proline knot, potential phosphorylation sites and haem-binding sites. Combined with their low expression, it is suggested that these caleosins may have lost function. PMID:26786939

  8. Sproglig Metode og Analyse

    DEFF Research Database (Denmark)

    le Fevre Jakobsen, Bjarne

    Publikationen indeholder øvematerialer, tekster, powerpointpræsentationer og handouts til undervisningsfaget Sproglig Metode og Analyse på BA og tilvalg i Dansk/Nordisk 2010-2011......Publikationen indeholder øvematerialer, tekster, powerpointpræsentationer og handouts til undervisningsfaget Sproglig Metode og Analyse på BA og tilvalg i Dansk/Nordisk 2010-2011...

  9. The Development of Protein Microarrays and Their Applications in DNA-Protein and Protein-Protein Interaction Analyses of Arabidopsis Transcription Factors

    Institute of Scientific and Technical Information of China (English)

    Wei Gong; Kun He; Mike Covington; S.R Dinesh-Kumar; Michael Snyder; Stacey L.Harmer; Yu-Xian Zhu; Xing Wang Deng

    2008-01-01

    We used our collection of Arabidopsis transcription factor (TF) ORFeome clones to constructprotein microarrays containing as many as 802 TF proteins. These protein microarrays were used for both protein-DNA and proteinprotein interaction analyses. For protein-DNA interaction studies, we examined AP2/ERF family TFs and their cognate cis-elements. By careful comparison of the DNA-binding specificity of 13 TFs on the protein microarray with previous non-microarray data, we showed that protein microarrays provide an efficient and high throughput tool for genome-wide analysis of TF-DNA interactions. This microarray protein-DNA interaction analysis allowed us to derive a comprehensive view of DNA-binding profiles of AP2/ERF family proteins in Arabidopsis. It also revealed four TFs that bound the EE (evening element) and had the expected phased gene expression under clock-regulation, thus providing a basis for further functional analysis of their roles in clock regulation of gene expression. We also developed procedures for detecting protein interactions using this TF protein microarray and discovered four novel partners that interact with HY5, which can be validated by yeast two-hybrid assays. Thus, plant TF protein microarrays offer an attractive high-throughput alternative to traditional techniques for TF functional characterization on a global scale.

  10. Mitogenomic analyses of eutherian relationships.

    Science.gov (United States)

    Arnason, U; Janke, A

    2002-01-01

    Reasonably correct phylogenies are fundamental to the testing of evolutionary hypotheses. Here, we present phylogenetic findings based on analyses of 67 complete mammalian mitochondrial (mt) genomes. The analyses, irrespective of whether they were performed at the amino acid (aa) level or on nucleotides (nt) of first and second codon positions, placed Erinaceomorpha (hedgehogs and their kin) as the sister group of remaining eutherians. Thus, the analyses separated Erinaceomorpha from other traditional lipotyphlans (e.g., tenrecs, moles, and shrews), making traditional Lipotyphla polyphyletic. Both the aa and nt data sets identified the two order-rich eutherian clades, the Cetferungulata (comprising Pholidota, Carnivora, Perissodactyla, Artiodactyla, and Cetacea) and the African clade (Tenrecomorpha, Macroscelidea, Tubulidentata, Hyracoidea, Proboscidea, and Sirenia). The study corroborated recent findings that have identified a sister-group relationship between Anthropoidea and Dermoptera (flying lemurs), thereby making our own order, Primates, a paraphyletic assembly. Molecular estimates using paleontologically well-established calibration points, placed the origin of most eutherian orders in Cretaceous times, 70-100 million years before present (MYBP). The same estimates place all primate divergences much earlier than traditionally believed. For example, the divergence between Homo and Pan is estimated to have taken place approximately 10 MYBP, a dating consistent with recent findings in primate paleontology.

  11. Mitogenomic analyses of eutherian relationships.

    Science.gov (United States)

    Arnason, U; Janke, A

    2002-01-01

    Reasonably correct phylogenies are fundamental to the testing of evolutionary hypotheses. Here, we present phylogenetic findings based on analyses of 67 complete mammalian mitochondrial (mt) genomes. The analyses, irrespective of whether they were performed at the amino acid (aa) level or on nucleotides (nt) of first and second codon positions, placed Erinaceomorpha (hedgehogs and their kin) as the sister group of remaining eutherians. Thus, the analyses separated Erinaceomorpha from other traditional lipotyphlans (e.g., tenrecs, moles, and shrews), making traditional Lipotyphla polyphyletic. Both the aa and nt data sets identified the two order-rich eutherian clades, the Cetferungulata (comprising Pholidota, Carnivora, Perissodactyla, Artiodactyla, and Cetacea) and the African clade (Tenrecomorpha, Macroscelidea, Tubulidentata, Hyracoidea, Proboscidea, and Sirenia). The study corroborated recent findings that have identified a sister-group relationship between Anthropoidea and Dermoptera (flying lemurs), thereby making our own order, Primates, a paraphyletic assembly. Molecular estimates using paleontologically well-established calibration points, placed the origin of most eutherian orders in Cretaceous times, 70-100 million years before present (MYBP). The same estimates place all primate divergences much earlier than traditionally believed. For example, the divergence between Homo and Pan is estimated to have taken place approximately 10 MYBP, a dating consistent with recent findings in primate paleontology. PMID:12438776

  12. Laser Beam Focus Analyser

    DEFF Research Database (Denmark)

    Nielsen, Peter Carøe; Hansen, Hans Nørgaard; Olsen, Flemming Ove;

    2007-01-01

    The quantitative and qualitative description of laser beam characteristics is important for process implementation and optimisation. In particular, a need for quantitative characterisation of beam diameter was identified when using fibre lasers for micro manufacturing. Here the beam diameter limits...... the obtainable features in direct laser machining as well as heat affected zones in welding processes. This paper describes the development of a measuring unit capable of analysing beam shape and diameter of lasers to be used in manufacturing processes. The analyser is based on the principle of a rotating...... mechanical wire being swept through the laser beam at varying Z-heights. The reflected signal is analysed and the resulting beam profile determined. The development comprised the design of a flexible fixture capable of providing both rotation and Z-axis movement, control software including data capture...

  13. Report sensory analyses veal

    OpenAIRE

    Veldman, M.; Schelvis-Smit, A.A.M.

    2005-01-01

    On behalf of a client of Animal Sciences Group, different varieties of veal were analyzed by both instrumental and sensory analyses. The sensory evaluation was performed with a sensory analytical panel in the period of 13th of May and 31st of May, 2005. The three varieties of veal were: young bull, pink veal and white veal. The sensory descriptive analyses show that the three groups Young bulls, pink veal and white veal, differ significantly in red colour for the raw meat as well as the baked...

  14. Meta-analyses

    NARCIS (Netherlands)

    Hendriks, M.A.; Luyten, J.W.; Scheerens, J.; Sleegers, P.J.C.; Scheerens, J.

    2014-01-01

    In this chapter results of a research synthesis and quantitative meta-analyses of three facets of time effects in education are presented, namely time at school during regular lesson hours, homework, and extended learning time. The number of studies for these three facets of time that could be used

  15. Probabilistic safety analyses (PSA)

    International Nuclear Information System (INIS)

    The guide shows how the probabilistic safety analyses (PSA) are used in the design, construction and operation of light water reactor plants in order for their part to ensure that the safety of the plant is good enough in all plant operational states

  16. Wavelet Analyses and Applications

    Science.gov (United States)

    Bordeianu, Cristian C.; Landau, Rubin H.; Paez, Manuel J.

    2009-01-01

    It is shown how a modern extension of Fourier analysis known as wavelet analysis is applied to signals containing multiscale information. First, a continuous wavelet transform is used to analyse the spectrum of a nonstationary signal (one whose form changes in time). The spectral analysis of such a signal gives the strength of the signal in each…

  17. Report sensory analyses veal

    NARCIS (Netherlands)

    Veldman, M.; Schelvis-Smit, A.A.M.

    2005-01-01

    On behalf of a client of Animal Sciences Group, different varieties of veal were analyzed by both instrumental and sensory analyses. The sensory evaluation was performed with a sensory analytical panel in the period of 13th of May and 31st of May, 2005. The three varieties of veal were: young bull,

  18. Possible future HERA analyses

    CERN Document Server

    Geiser, Achim

    2015-01-01

    A variety of possible future analyses of HERA data in the context of the HERA data preservation programme is collected, motivated, and commented. The focus is placed on possible future analyses of the existing $ep$ collider data and their physics scope. Comparisons to the original scope of the HERA programme are made, and cross references to topics also covered by other participants of the workshop are given. This includes topics on QCD, proton structure, diffraction, jets, hadronic final states, heavy flavours, electroweak physics, and the application of related theory and phenomenology topics like NNLO QCD calculations, low-x related models, nonperturbative QCD aspects, and electroweak radiative corrections. Synergies with other collider programmes are also addressed. In summary, the range of physics topics which can still be uniquely covered using the existing data is very broad and of considerable physics interest, often matching the interest of results from colliders currently in operation. Due to well-e...

  19. Statistisk analyse med SPSS

    OpenAIRE

    Linnerud, Kristin; Oklevik, Ove; Slettvold, Harald

    2004-01-01

    Dette notatet har sitt utspring i forelesninger og undervisning for 3.års studenter i økonomi og administrasjon ved høgskolen i Sogn og Fjordane. Notatet er særlig lagt opp mot undervisningen i SPSS i de to kursene ”OR 685 Marknadsanalyse og merkevarestrategi” og ”BD 616 Økonomistyring og analyse med programvare”.

  20. Biomass feedstock analyses

    Energy Technology Data Exchange (ETDEWEB)

    Wilen, C.; Moilanen, A.; Kurkela, E. [VTT Energy, Espoo (Finland). Energy Production Technologies

    1996-12-31

    The overall objectives of the project `Feasibility of electricity production from biomass by pressurized gasification systems` within the EC Research Programme JOULE II were to evaluate the potential of advanced power production systems based on biomass gasification and to study the technical and economic feasibility of these new processes with different type of biomass feed stocks. This report was prepared as part of this R and D project. The objectives of this task were to perform fuel analyses of potential woody and herbaceous biomasses with specific regard to the gasification properties of the selected feed stocks. The analyses of 15 Scandinavian and European biomass feed stock included density, proximate and ultimate analyses, trace compounds, ash composition and fusion behaviour in oxidizing and reducing atmospheres. The wood-derived fuels, such as whole-tree chips, forest residues, bark and to some extent willow, can be expected to have good gasification properties. Difficulties caused by ash fusion and sintering in straw combustion and gasification are generally known. The ash and alkali metal contents of the European biomasses harvested in Italy resembled those of the Nordic straws, and it is expected that they behave to a great extent as straw in gasification. Any direct relation between the ash fusion behavior (determined according to the standard method) and, for instance, the alkali metal content was not found in the laboratory determinations. A more profound characterisation of the fuels would require gasification experiments in a thermobalance and a PDU (Process development Unit) rig. (orig.) (10 refs.)

  1. Possible future HERA analyses

    Energy Technology Data Exchange (ETDEWEB)

    Geiser, Achim

    2015-12-15

    A variety of possible future analyses of HERA data in the context of the HERA data preservation programme is collected, motivated, and commented. The focus is placed on possible future analyses of the existing ep collider data and their physics scope. Comparisons to the original scope of the HERA pro- gramme are made, and cross references to topics also covered by other participants of the workshop are given. This includes topics on QCD, proton structure, diffraction, jets, hadronic final states, heavy flavours, electroweak physics, and the application of related theory and phenomenology topics like NNLO QCD calculations, low-x related models, nonperturbative QCD aspects, and electroweak radiative corrections. Synergies with other collider programmes are also addressed. In summary, the range of physics topics which can still be uniquely covered using the existing data is very broad and of considerable physics interest, often matching the interest of results from colliders currently in operation. Due to well-established data and MC sets, calibrations, and analysis procedures the manpower and expertise needed for a particular analysis is often very much smaller than that needed for an ongoing experiment. Since centrally funded manpower to carry out such analyses is not available any longer, this contribution not only targets experienced self-funded experimentalists, but also theorists and master-level students who might wish to carry out such an analysis.

  2. PRE-1, a cis element sufficient to enhance cone- and rod- specific expression in differentiating zebrafish photoreceptors

    Directory of Open Access Journals (Sweden)

    Hurley James B

    2011-01-01

    Full Text Available Abstract Background Appropriate transcriptional regulation is required for cone photoreceptor development and integrity. To date, only a few cis-regulatory elements that control cone photoreceptor-specific expression have been characterised. The alpha-subunit of cone transducin (TαC is specifically expressed in cone photoreceptors and is required for colour vision. In order to better understand the molecular genetics controlling the initiation of cone photoreceptor-specific expression in vivo, we have utilised zebrafish to identify cis-regulatory elements in the upstream promoter region of the TαC gene. Results A 0.5 kb TαC promoter fragment is sufficient to direct cone-specific expression in transgenic larvae. Within this minimal promoter, we identify photoreceptor regulatory element-1 (PRE-1, a unique 41 bp sequence. PRE-1 specifically binds nuclear factors expressed in ocular tissue. PRE-1 is not required for cone-specific expression directed from a 2.5 kb TαC promoter. However, PRE-1-like sequences, with potential functional redundancy, are located in this 2.5 kb promoter. PRE-1-rho which has the highest sequence and structural homology to PRE-1 is located in the rhodopsin promoter. Surprisingly, PRE-1 and PRE-1-rho are functionally distinct. We demonstrate that PRE-1, but not PRE-1-rho, is sufficient to enhance expression from a heterologous UV cone promoter. PRE-1 is also sufficient to enhance expression from a heterologous rhodopsin promoter without altering its rod photoreceptor specificity. Finally, mutations in consensus E-box and Otx sites prevent PRE-1 from forming complexes with eye nuclear protein and enhancing photoreceptor expression. Conclusions PRE-1 is a novel cis-regulatory module that is sufficient to enhance the initiation of photoreceptor-specific gene expression in differentiating rod and cone photoreceptors.

  3. Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution

    DEFF Research Database (Denmark)

    Richards, Stephen; Liu, Yue; Bettencourt, Brian R.;

    2005-01-01

    years (Myr) since the pseudoobscura/melanogaster divergence. Genes expressed in the testes had higher amino acid sequence divergence than the genome-wide average, consistent with the rapid evolution of sex-specific proteins. Cis-regulatory sequences are more conserved than random and nearby sequences......We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout evolution the vast majority of Drosophila genes have remained on the same chromosome arm, but within each...... between the species-but the difference is slight, suggesting that the evolution of cis-regulatory elements is flexible. Overall, a pattern of repeat-mediated chromosomal rearrangement, and high coadaptation of both male genes and cis-regulatory sequences emerges as important themes of genome divergence...

  4. Digital differential analysers

    CERN Document Server

    Shilejko, A V; Higinbotham, W

    1964-01-01

    Digital Differential Analysers presents the principles, operations, design, and applications of digital differential analyzers, a machine with the ability to present initial quantities and the possibility of dividing them into separate functional units performing a number of basic mathematical operations. The book discusses the theoretical principles underlying the operation of digital differential analyzers, such as the use of the delta-modulation method and function-generator units. Digital integration methods and the classes of digital differential analyzer designs are also reviewed. The te

  5. Wavelet analyses and applications

    Energy Technology Data Exchange (ETDEWEB)

    Bordeianu, Cristian C [Faculty of Physics, University of Bucharest, Bucharest, RO 077125 (Romania); Landau, Rubin H [Department of Physics, Oregon State University, Corvallis, OR 97331 (United States); Paez, Manuel J [Department of Physics, University of Antioquia, Medellin (Colombia)], E-mail: cristian.bordeianu@brahms.fizica.unibuc.ro, E-mail: rubin@science.oregonstate.edu, E-mail: mpaez@fisica.udea.edu.co

    2009-09-15

    It is shown how a modern extension of Fourier analysis known as wavelet analysis is applied to signals containing multiscale information. First, a continuous wavelet transform is used to analyse the spectrum of a nonstationary signal (one whose form changes in time). The spectral analysis of such a signal gives the strength of the signal in each frequency as a function of time. Next, the theory is specialized to discrete values of time and frequency, and the resulting discrete wavelet transform is shown to be useful for data compression. This paper is addressed to a broad community, from undergraduate to graduate students to general physicists and to specialists in other fields than wavelets.

  6. Systemdynamisk analyse av vannkraftsystem

    OpenAIRE

    Rydning, Anja

    2007-01-01

    I denne oppgaven er det gjennomført en dynamisk analyse av vannkraftverket Fortun kraftverk. Tre fenomener er særlig vurdert i denne oppgaven: Sjaktsvingninger mellom svingesjakt og magasin, trykkstøt ved turbinen som følge av retardasjonstrykk ved endring i turbinvannføringen og reguleringsstabilitet. Sjaktsvingningene og trykkstøt beregnes analytisk ut fra kontinuitets- og bevegelsesligningen. Modeller av Fortun kraftverk er laget for å beregne trykkstøt og sjaktsvingninger. En modell e...

  7. AMS analyses at ANSTO

    Energy Technology Data Exchange (ETDEWEB)

    Lawson, E.M. [Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia). Physics Division

    1998-03-01

    The major use of ANTARES is Accelerator Mass Spectrometry (AMS) with {sup 14}C being the most commonly analysed radioisotope - presently about 35 % of the available beam time on ANTARES is used for {sup 14}C measurements. The accelerator measurements are supported by, and dependent on, a strong sample preparation section. The ANTARES AMS facility supports a wide range of investigations into fields such as global climate change, ice cores, oceanography, dendrochronology, anthropology, and classical and Australian archaeology. Described here are some examples of the ways in which AMS has been applied to support research into the archaeology, prehistory and culture of this continent`s indigenous Aboriginal peoples. (author)

  8. Characterizing configurations of fire ignition points through spatiotemporal point processes

    Science.gov (United States)

    Comas, C.; Costafreda-Aumedes, S.; Vega-Garcia, C.

    2014-04-01

    Human-caused forest fires are usually regarded as unpredictable but often exhibit trends towards clustering in certain locations and periods. Characterizing such configurations is crucial for understanding spatiotemporal fire dynamics and implementing preventive actions. Our objectives were to analyse the spatiotemporal point configuration and to test for spatiotemporal interaction. We characterized the spatiotemporal structure of 984 fire ignition points in a study area of Galicia, Spain, during 2007-2011 by the K-Ripley's function. Our results suggest the presence of spatiotemporal structures for time lags of less than two years and ignition point distances in the range 0-12 km. Ignition centre points at time lags of less than 100 days are aggregated for any inter-event distance. This cluster structure loses strength as the time lag increases, and at time lags of more than 365 days this cluster structure is not significant for any lag distance. Our results also suggest spatiotemporal interdependencies at time lags of less than 100 days and inter-event distances of less than 10 km. At time lags of up to 365 days spatiotemporal components are independent for any point distance. These results suggest that risk conditions occur locally and are short-lived in this study area.

  9. Attitude stability analyses for small artificial satellites

    International Nuclear Information System (INIS)

    The objective of this paper is to analyze the stability of the rotational motion of a symmetrical spacecraft, in a circular orbit. The equilibrium points and regions of stability are established when components of the gravity gradient torque acting on the spacecraft are included in the equations of rotational motion, which are described by the Andoyer's variables. The nonlinear stability of the equilibrium points of the rotational motion is analysed here by the Kovalev-Savchenko theorem. With the application of the Kovalev-Savchenko theorem, it is possible to verify if they remain stable under the influence of the terms of higher order of the normal Hamiltonian. In this paper, numerical simulations are made for a small hypothetical artificial satellite. Several stable equilibrium points were determined and regions around these points have been established by variations in the orbital inclination and in the spacecraft principal moment of inertia. The present analysis can directly contribute in the maintenance of the spacecraft's attitude

  10. EEG analyses with SOBI.

    Energy Technology Data Exchange (ETDEWEB)

    Glickman, Matthew R.; Tang, Akaysha (University of New Mexico, Albuquerque, NM)

    2009-02-01

    The motivating vision behind Sandia's MENTOR/PAL LDRD project has been that of systems which use real-time psychophysiological data to support and enhance human performance, both individually and of groups. Relevant and significant psychophysiological data being a necessary prerequisite to such systems, this LDRD has focused on identifying and refining such signals. The project has focused in particular on EEG (electroencephalogram) data as a promising candidate signal because it (potentially) provides a broad window on brain activity with relatively low cost and logistical constraints. We report here on two analyses performed on EEG data collected in this project using the SOBI (Second Order Blind Identification) algorithm to identify two independent sources of brain activity: one in the frontal lobe and one in the occipital. The first study looks at directional influences between the two components, while the second study looks at inferring gender based upon the frontal component.

  11. Characterization and simulation of fate and transport of selected volatile organic compounds in the vicinities of the Hadnot Point Industrial Area and landfill: Chapter A Supplement 6 in Analyses and historical reconstruction of groundwater flow, contaminant fate and transport, and distribution of drinking water within the service areas of the Hadnot Point and Holcomb Boulevard Water Treatment Plants and vicinities, U.S. Marine Corps Base Camp Lejeune, North Carolina

    Science.gov (United States)

    Jones, L. Elliott; Suárez-Soto, René J.; Anderson, Barbara A.; Maslia, Morris L.

    2013-01-01

    This supplement of Chapter A (Supplement 6) describes the reconstruction (i.e. simulation) of historical concentrations of tetrachloroethylene (PCE), trichloroethylene (TCE), and benzene3 in production wells supplying water to the Hadnot Base (USMCB) Camp Lejeune, North Carolina (Figure S6.1). A fate and transport model (i.e., MT3DMS [Zheng and Wang 1999]) was used to simulate contaminant migration from source locations through the groundwater system and to estimate mean contaminant concentrations in water withdrawn from water-supply wells in the vicinity of the Hadnot Point Industrial Area (HPIA) and the Hadnot Point landfill (HPLF) area.4 The reconstructed contaminant concentrations were subsequently input into a flow-weighted, materials mass balance (mixing) model (Masters 1998) to estimate monthly mean concentrations of the contaminant in finished water 5 at the HPWTP (Maslia et al. 2013). The calibrated fate and transport models described herein were based on and used groundwater velocities derived from groundwater-flow models that are described in Suárez-Soto et al. (2013). Information data pertinent to historical operations of water-supply wells are described in Sautner et al. (2013) and Telci et al. (2013).

  12. ENSO Indices and Analyses

    Institute of Scientific and Technical Information of China (English)

    WANG Zhiren; WU Dexing; CHEN Xue'en; QIAO Ran

    2013-01-01

    New ENSO indices were developed and the spatial variability and temporal evolution of ENSO were analyzed based on the new indices and modeling experiments,as well as multiple data resources.The new indices,after being defined,were validated with their good diagnostic characteristics and correlation with wind and SST.In the analysis after the definition and validation of the new indices,ENSO feedbacks from wind,heat fluxes,and precipitation were spatially and temporally examined in order to understand ENSO variability and evolution with some emphasized points such as the interaction among the feedbacks,the role of westerly wind bursts and the transformation between zonal and meridional circulations in an ENSO cycle,and the typical pattern of modern ENSO.

  13. Analysing ESP Texts, but How?

    Directory of Open Access Journals (Sweden)

    Borza Natalia

    2015-03-01

    Full Text Available English as a second language (ESL teachers instructing general English and English for specific purposes (ESP in bilingual secondary schools face various challenges when it comes to choosing the main linguistic foci of language preparatory courses enabling non-native students to study academic subjects in English. ESL teachers intending to analyse English language subject textbooks written for secondary school students with the aim of gaining information about what bilingual secondary school students need to know in terms of language to process academic textbooks cannot avoiding deal with a dilemma. It needs to be decided which way it is most appropriate to analyse the texts in question. Handbooks of English applied linguistics are not immensely helpful with regard to this problem as they tend not to give recommendation as to which major text analytical approaches are advisable to follow in a pre-college setting. The present theoretical research aims to address this lacuna. Respectively, the purpose of this pedagogically motivated theoretical paper is to investigate two major approaches of ESP text analysis, the register and the genre analysis, in order to find the more suitable one for exploring the language use of secondary school subject texts from the point of view of an English as a second language teacher. Comparing and contrasting the merits and limitations of the two contrastive approaches allows for a better understanding of the nature of the two different perspectives of text analysis. The study examines the goals, the scope of analysis, and the achievements of the register perspective and those of the genre approach alike. The paper also investigates and reviews in detail the starkly different methods of ESP text analysis applied by the two perspectives. Discovering text analysis from a theoretical and methodological angle supports a practical aspect of English teaching, namely making an informed choice when setting out to analyse

  14. Website-analyse

    DEFF Research Database (Denmark)

    Thorlacius, Lisbeth

    2009-01-01

    planlægning af de funktionelle og indholdsmæssige aspekter ved websites. Der findes en stor mængde teori- og metodebøger, som har specialiseret sig i de tekniske problemstillinger i forbindelse med interaktion og navigation, samt det sproglige indhold på websites. Den danske HCI (Human Computer Interaction...... hyperfunktionelle websites. Det primære ærinde for HCI-eksperterne er at udarbejde websites, som er brugervenlige. Ifølge deres direktiver skal websites være opbygget med hurtige og effektive navigations- og interaktionsstrukturer, hvor brugeren kan få sine informationer ubesværet af lange downloadingshastigheder...... eller blindgyder, når han/hun besøger sitet. Studier i design og analyse af de visuelle og æstetiske aspekter i planlægning og brug af websites har imidlertid kun i et begrænset omfang været under reflektorisk behandling. Det er baggrunden for dette kapitel, som indleder med en gennemgang af æstetikkens...

  15. Point by Point: Adding up Motivation

    Science.gov (United States)

    Marchionda, Denise

    2010-01-01

    Students often view their course grades as a mysterious equation of teacher-given grades, teacher-given grace, and some other ethereal components based on luck. However, giving students the power to earn points based on numerous daily/weekly assignments and attendance makes the grading process objective and personal, freeing the instructor to…

  16. Properties of residuals for spatial point processes

    DEFF Research Database (Denmark)

    Baddeley, A.; Møller, Jesper; Pakes, A.G.

    For any point process in $R^d$ that has a Papangelou conditional intensity $lambda$, we define a random measure of ‘innovations’ which has mean zero. When the point process model parameters are estimated from data, there is an analogous random measure of ‘residuals’. We analyse properties of the...... innovations and residuals, including first and second moments, conditional independence, a martingale property, lack of correlation, and marginal distributions....

  17. Biodégradation de matériaux polymères à usage agricole : Etude et mise au point d'une nouvelle méthode de test, analyse des produits de dégradation et impact environnemental

    OpenAIRE

    Grima, S.

    2002-01-01

    The issues associated with solid waste continuous increase, impacting the environment as well as regulations about non-ultimate waste created a real interest in biodegradable polymer materials. Before using intensively these materials, it is necessary to check that they are harmless to the environment. To achieve this objective, analyses on by-products and residues resulting from biodegradation were performed. A thorough study on agricultural plastic films was conducted. First, a biodegradati...

  18. Arctic Climate Tipping Points

    OpenAIRE

    Lenton, Timothy M.

    2012-01-01

    There is widespread concern that anthropogenic global warming will trigger Arctic climate tipping points. The Arctic has a long history of natural, abrupt climate changes, which together with current observations and model projections, can help us to identify which parts of the Arctic climate system might pass future tipping points. Here the climate tipping points are defined, noting that not all of them involve bifurcations leading to irreversible change. Past abrupt climate changes in the A...

  19. Severe Accident Recriticality Analyses (SARA)

    Energy Technology Data Exchange (ETDEWEB)

    Frid, W. [Swedish Nuclear Power Inspectorate, Stockholm (Sweden); Hoejerup, F. [Risoe National Lab. (Denmark); Lindholm, I.; Miettinen, J.; Puska, E.K. [VTT Energy, Helsinki (Finland); Nilsson, Lars [Studsvik Eco and Safety AB, Nykoeping (Sweden); Sjoevall, H. [Teoliisuuden Voima Oy (Finland)

    1999-11-01

    Recriticality in a BWR has been studied for a total loss of electric power accident scenario. In a BWR, the B{sub 4}C control rods would melt and relocate from the core before the fuel during core uncovery and heat-up. If electric power returns during this time-window unborated water from ECCS systems will start to reflood the partly control rod free core. Recriticality might take place for which the only mitigating mechanisms are the Doppler effect and void formation. In order to assess the impact of recriticality on reactor safety, including accident management measures, the following issues have been investigated in the SARA project: 1. the energy deposition in the fuel during super-prompt power burst, 2. the quasi steady-state reactor power following the initial power burst and 3. containment response to elevated quasi steady-state reactor power. The approach was to use three computer codes and to further develop and adapt them for the task. The codes were SIMULATE-3K, APROS and RECRIT. Recriticality analyses were carried out for a number of selected reflooding transients for the Oskarshamn 3 plant in Sweden with SIMULATE-3K and for the Olkiluoto 1 plant in Finland with all three codes. The core state initial and boundary conditions prior to recriticality have been studied with the severe accident codes SCDAP/RELAP5, MELCOR and MAAP4. The results of the analyses show that all three codes predict recriticality - both superprompt power bursts and quasi steady-state power generation - for the studied range of parameters, i. e. with core uncovery and heat-up to maximum core temperatures around 1800 K and water flow rates of 45 kg/s to 2000 kg/s injected into the downcomer. Since the recriticality takes place in a small fraction of the core the power densities are high which results in large energy deposition in the fuel during power burst in some accident scenarios. The highest value, 418 cal/g, was obtained with SIMULATE-3K for an Oskarshamn 3 case with reflooding

  20. Finite element analyses of CCAT preliminary design

    Science.gov (United States)

    Sarawit, Andrew T.; Kan, Frank W.

    2014-07-01

    This paper describes the development of the CCAT telescope finite element model (FEM) and the analyses performed to support the preliminary design work. CCAT will be a 25 m diameter telescope operating in the 0.2 to 2 mm wavelength range. It will be located at an elevation of 5600 m on Cerro Chajnantor in Northern Chile, near ALMA. The telescope will be equipped with wide-field cameras and spectrometers mounted at the two Nasmyth foci. The telescope will be inside an enclosure to protect it from wind buffeting, direct solar heating, and bad weather. The main structures of the telescope include a steel Mount and a carbon-fiber-reinforced-plastic (CFRP) primary truss. The finite element model developed in this study was used to perform modal, frequency response, seismic response spectrum, stress, and deflection analyses of telescope. Modal analyses of telescope were performed to compute the structure natural frequencies and mode shapes and to obtain reduced order modal output at selected locations in the telescope structure to support the design of the Mount control system. Modal frequency response analyses were also performed to compute transfer functions at these selected locations. Seismic response spectrum analyses of the telescope subject to the Maximum Likely Earthquake were performed to compute peak accelerations and seismic demand stresses. Stress analyses were performed for gravity load to obtain gravity demand stresses. Deflection analyses for gravity load, thermal load, and differential elevation drive torque were performed so that the CCAT Observatory can verify that the structures meet the stringent telescope surface and pointing error requirements.

  1. Indexing Moving Points

    DEFF Research Database (Denmark)

    Agarwal, Pankaj K.; Arge, Lars Allan; Erickson, Jeff

    2003-01-01

    We propose three indexing schemes for storing a set S of N points in the plane, each moving along a linear trajectory, so that any query of the following form can be answered quickly: Given a rectangle R and a real value t, report all K points of S that lie inside R at time t. We first present an...

  2. Nickel Curie Point Engine

    Science.gov (United States)

    Chiaverina, Chris; Lisensky, George

    2014-01-01

    Ferromagnetic materials such as nickel, iron, or cobalt lose the electron alignment that makes them attracted to a magnet when sufficient thermal energy is added. The temperature at which this change occurs is called the "Curie temperature," or "Curie point." Nickel has a Curie point of 627 K, so a candle flame is a sufficient…

  3. Sunspot Bright Points

    CERN Document Server

    Choudhary, Debi Prasad

    2010-01-01

    We used the flux calibrated images through the Broad Band Filter Imager and Stokes Polarimeter data obtained with the Solar Optical Telescope onboard the Hinode spacecraft to study the properties of bright points in and around the sunspots. The well isolated bright points were selected and classified as umbral dot, peripheral umbral dot, penumbral grains and G-band bright point depending on their location. Most of the bright points are smaller than about 150 km. The larger points are mostly associated with the penumbral features. The bright points are not uniformly distributed over the umbra but preferentially located around the penumbral boundary and in the fast decaying parts of umbra. The color temperature of the bright points, derived using the continuum irradiance, are in the range of 4600 K to 6600 K with cooler ones located in the umbra. The temperature increases as a function of distance from the center to outside. The G-band, CN-band and CaII H flux of the bright points as a function of their blue ba...

  4. Model Breaking Points Conceptualized

    Science.gov (United States)

    Vig, Rozy; Murray, Eileen; Star, Jon R.

    2014-01-01

    Current curriculum initiatives (e.g., National Governors Association Center for Best Practices and Council of Chief State School Officers 2010) advocate that models be used in the mathematics classroom. However, despite their apparent promise, there comes a point when models break, a point in the mathematical problem space where the model cannot,…

  5. Do acupuncture points exist?

    Energy Technology Data Exchange (ETDEWEB)

    Yan Xiaohui; Zhang Xinyi [Department of Physics, Surface Physics Laboratory (State Key Laboratory), and Synchrotron Radiation Research Center of Fudan University, Shanghai 200433 (China); Liu Chenglin [Physics Department of Yancheng Teachers' College, Yancheng 224002 (China); Dang, Ruishan [Second Military Medical University, Shanghai 200433 (China); Huang Yuying; He Wei [Beijing Synchrotron Radiation Facility, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100039 (China); Ding Guanghong [Shanghai Research Center of Acupuncture and Meridian, Pudong, Shanghai 201203 (China)

    2009-05-07

    We used synchrotron x-ray fluorescence analysis to probe the distribution of four chemical elements in and around acupuncture points, two located in the forearm and two in the lower leg. Three of the four acupuncture points showed significantly elevated concentrations of elements Ca, Fe, Cu and Zn in relation to levels in the surrounding tissue, with similar elevation ratios for Cu and Fe. The mapped distribution of these elements implies that each acupuncture point seems to be elliptical with the long axis along the meridian. (note)

  6. Allegheny County Address Points

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset contains address points which represent physical address locations assigned by the Allegheny County addressing authority. Data is updated by County...

  7. Designated Wildlife Lakes - points

    Data.gov (United States)

    Minnesota Department of Natural Resources — This is a point shapefile of Designated Wildlife Lakes in Minnesota. This shapefile was created by converting lake polygons from the Designated Wildlife Lakes...

  8. Triple Point Topological Metals

    Science.gov (United States)

    Zhu, Ziming; Winkler, Georg W.; Wu, QuanSheng; Li, Ju; Soluyanov, Alexey A.

    2016-07-01

    Topologically protected fermionic quasiparticles appear in metals, where band degeneracies occur at the Fermi level, dictated by the band structure topology. While in some metals these quasiparticles are direct analogues of elementary fermionic particles of the relativistic quantum field theory, other metals can have symmetries that give rise to quasiparticles, fundamentally different from those known in high-energy physics. Here, we report on a new type of topological quasiparticles—triple point fermions—realized in metals with symmorphic crystal structure, which host crossings of three bands in the vicinity of the Fermi level protected by point group symmetries. We find two topologically different types of triple point fermions, both distinct from any other topological quasiparticles reported to date. We provide examples of existing materials that host triple point fermions of both types and discuss a variety of physical phenomena associated with these quasiparticles, such as the occurrence of topological surface Fermi arcs, transport anomalies, and topological Lifshitz transitions.

  9. Transitivity on Weierstrass points

    CERN Document Server

    Laing, Zoe

    2010-01-01

    We look for Riemann surfaces whose automorphism group acts transitively on the Weierstrass points. We concentrate on hyperelliptic surfaces, surfaces with PSL(2, q) as automorphism group, Platonic surfaces and Fermat curves.

  10. National Wetlands Inventory Points

    Data.gov (United States)

    Minnesota Department of Natural Resources — Wetland point features (typically wetlands that are too small to be as area features at the data scale) mapped as part of the National Wetlands Inventory (NWI). The...

  11. Pratique de l'analyse fonctionelle

    CERN Document Server

    Tassinari, Robert

    1997-01-01

    Mettre au point un produit ou un service qui soit parfaitement adapté aux besoins et aux exigences du client est indispensable pour l'entreprise. Pour ne rien laisser au hasard, il s'agit de suivre une méthodologie rigoureuse : celle de l'analyse fonctionnelle. Cet ouvrage définit précisément cette méthode ainsi que ses champs d'application. Il décrit les méthodes les plus performantes en termes de conception de produit et de recherche de qualité et introduit la notion d'analyse fonctionnelle interne. Un ouvrage clé pour optimiser les processus de conception de produit dans son entreprise. -- Idées clés, par Business Digest

  12. Characterization of MIPAS elevation pointing

    Directory of Open Access Journals (Sweden)

    M. Kiefer

    2007-01-01

    Full Text Available Sufficient knowledge of the pointing is essential for analyses of limb emission measurements. The scientific retrieval processor for MIPAS on ENVISAT operated at IMK allows the retrieval of pointing information in terms of tangent altitudes along with temperature. The retrieved tangent altitudes are independent of systematic offsets in the engineering Line-Of-Sight (LOS information delivered with the ESA Level 1b product. The difference of pointing retrieved from the reprocessed high resolution MIPAS spectra and the engineering pointing information was examined with respect to spatial/temporal behaviour. Among others the following characteristics of MIPAS pointing could be identified: Generally the engineering tangent altitudes are too high by 0–1.8 km with conspicuous variations in this range over time. Prior to December of 2003 there was a drift of about 50–100 m/h, which was due to a slow change in the satellite attitude. A correction of this attitude is done twice a day, which leads to discontinuities in the order of 1–1.5 km in the tangent altitudes. Occasionally discontinuities up to 2.5 km are found, as already reported from MIPAS and SCIAMACHY observations. After an update of the orbit position software in December 2003 values of drift and jumps are much reduced. There is a systematic difference in the mispointing between the poles which amounts to 1.5–2 km, i.e. there is a conspicuous orbit-periodic feature. The analysis of the correlation between the instrument's viewing angle azimuth and differential mispointing supports the hypotheses that a major part of this latter phenomenon can be attributed to an error in the roll angle of the satellite/instrument system of approximately 42 mdeg. One conclusion is that ESA level 2 data should be compared to other data exclusively on tangent pressure levels. Complementary to IMK data, ESA operational LOS calibration results were used to characterize MIPAS pointing. For this purpose

  13. Characterization of MIPAS elevation pointing

    Science.gov (United States)

    Kiefer, M.; von Clarmann, T.; Grabowski, U.; de Laurentis, M.; Mantovani, R.; Milz, M.; Ridolfi, M.

    2007-03-01

    Sufficient knowledge of the pointing is essential for analyses of limb emission measurements. The scientific retrieval processor for MIPAS on ENVISAT operated at IMK allows the retrieval of pointing information in terms of tangent altitudes along with temperature. The retrieved tangent altitudes are independent of systematic offsets in the engineering Line-Of-Sight (LOS) information delivered with the ESA Level 1b product. The difference of pointing retrieved from the reprocessed high resolution MIPAS spectra and the engineering pointing information was examined with respect to spatial/temporal behaviour. Among others the following characteristics of MIPAS pointing could be identified: Generally the engineering tangent altitudes are too high by 0-1.8 km with conspicuous variations in this range over time. Prior to December of 2003 there was a drift of about 50-100 m/h, which was due to a slow change in the satellite attitude. A correction of this attitude is done twice a day, which leads to discontinuities in the order of 1-1.5 km in the tangent altitudes. Occasionally discontinuities up to 2.5 km are found, as already reported from MIPAS and SCIAMACHY observations. After an update of the orbit position software in December 2003 values of drift and jumps are much reduced. There is a systematic difference in the mispointing between the poles which amounts to 1.5-2 km, i.e. there is a conspicuous orbit-periodic feature. The analysis of the correlation between the instrument's viewing angle azimuth and differential mispointing supports the hypotheses that a major part of this latter phenomenon can be attributed to an error in the roll angle of the satellite/instrument system of approximately 42 mdeg. One conclusion is that ESA level 2 data should be compared to other data exclusively on tangent pressure levels. Complementary to IMK data, ESA operational LOS calibration results were used to characterize MIPAS pointing. For this purpose MIPAS is used as a radiometer

  14. Rod Ellis, Gary Barkhuizen, Analysing Learner Language

    OpenAIRE

    Narcy-Combes, Marie-Françoise

    2014-01-01

    Ce livre vient à point nommé pour compléter les outils à la disposition des jeunes chercheurs en linguistique appliquée et didactique des langues, comme des praticiens de terrain désireux de conduire une recherche-action. Comme souvent en ce qui concerne les ouvrages de Rod Ellis, il s’agit d’une somme : une étude diachronique des outils utilisés depuis les années soixante par les chercheurs en acquisition des langues pour l’analyse des productions écrites et orales des apprenants de langue. ...

  15. Seismic stability analyses - embankment dams

    Energy Technology Data Exchange (ETDEWEB)

    Boudreau, Stephane; Boulanger, Pierre; Caron, Louis Philippe [BPR, Montreal, (Canada); Karray, Mourad [Sherbrooke University, Sherbrooke, (Canada)

    2010-07-01

    An understanding of the effect of earthquakes is necessary to the design of safe dams. A wide number of methods are currently used or being developed for analysing the dynamic slop stability of embankments/dams. This paper investigated the effects of the dynamic aspects (natural period, amplifications and intensity of seismic loading) in the analysis of small dams. A procedure was developed to evaluate the performance of pseudo-static analyses by comparison with fully dynamic analyses. Static, pseudo-static, and dynamic analyses were performed using finite elements and Mohr-Coulomb shear strength criteria. The overall safety factor (FS) was compared using the reduction factor concept. The study worked on two examples of small dams located at moderate and violent seismic regions in the province of Quebec. These examples illustrated the difference between pseudo-static and dynamic analyses. The study also investigated the values of the kh coefficient for Eastern Canada seismicity.

  16. Holographic Three point Functions

    DEFF Research Database (Denmark)

    Bissi, Agnese

    gravitons and a point like graviton and its dual counterpart, namely two Schur polynomials and a single trace chiral primary. Secondly we compute the one loop correction to planar, non extremal three point functions of two heavy and one light operators, both from the gauge and string side in the Frolov......In this thesis it is addressed the problem of the computation of three point correlation functions within the AdS=CFT correspondence. In the context of the AdS 5=CFT4 correspondence we present three computations. First we compare the results of tree level three point functions of two giant......-Tseytlin regime. Finally we generalize the scalar product of two states belonging to the SO(6) sector of N = 4 SYM with implications on the construction of three point functions of 3 non-BPS operators from the gauge theory side. On the other hand in the AdS4=CFT3 correspondence we compare the computations...

  17. Layered Fixed Point Logic

    DEFF Research Database (Denmark)

    Filipiuk, Piotr; Nielson, Flemming; Nielson, Hanne Riis

    2012-01-01

    are a Moore Family result and a parametrized worst case time complexity result. We show that the logic and the associated solver can be used for rapid prototyping of analyses and illustrate a wide variety of applications within Static Analysis, Constraint Satisfaction Problems and Model Checking. In all cases...

  18. Countermeasure analyses on selection and cultivation of the new economic growth points in resource-based city of Northern Shaanxi%陕北资源型城市选择和培育新经济增长点的对策分析

    Institute of Scientific and Technical Information of China (English)

    徐长玉; 李娟

    2012-01-01

    国家实施西部大开发战略以来,陕北资源型城市依托矿产资源开采,不仅摘掉了国家级贫困地区的帽子,而且主要经济指标从陕西后列排在前列。然而,随着资源的过度开采,陕北资源型城市却陷入了资源濒临枯竭,经济发展后劲不足的困难局面。因此,陕北各级政府只有通过选择和培育接续产业,积极采取各种应对措施,才能实现陕北资源型城市持续向好发展。%Since the implementation of Western Development Strategy,depending on exploitation of mineral resources,the resource-based city of Northern Shaanxi has not only got rid of the title of "state-level poverty-stricken area",but also ranked ahead from behind in its main economic indicators in Shaanxi province.However,with the overexploitation of resources,the resource-based city of Northern Shaanxi has bogged down to a dilemma of exhaustion of resources and constraint of economic development.Therefore,the governments at all levels in Northern Shaanxi have to select and breed new economic growth points and actively take all appropriate measures in order to achieve the comprehensive,coordinated and sustainable

  19. Feed analyses and their interpretation.

    Science.gov (United States)

    Hall, Mary Beth

    2014-11-01

    Compositional analysis is central to determining the nutritional value of feedstuffs for use in ration formulation. The utility of the values and how they should be used depends on how representative the feed subsample is, the nutritional relevance and analytical variability of the assays, and whether an analysis is suitable to be applied to a particular feedstuff. Commercial analyses presently available for carbohydrates, protein, and fats have improved nutritionally pertinent description of feed fractions. Factors affecting interpretation of feed analyses and the nutritional relevance and application of currently available analyses are discussed.

  20. New Novae snack point

    CERN Multimedia

    2012-01-01

    Located next to the car park by the flag poles, a few metres from the Main CERN Reception (building 33), a new snack point catered by Novae will open to the public on Wednesday 8 August. More information will be available in the next issue of the Bulletin!

  1. Point kinetics modeling

    International Nuclear Information System (INIS)

    A normalized form of the point kinetics equations, a prompt jump approximation, and the Nordheim-Fuchs model are used to model nuclear systems. Reactivity feedback mechanisms considered include volumetric expansion, thermal neutron temperature effect, Doppler effect and void formation. A sample problem of an excursion occurring in a plutonium solution accidentally formed in a glovebox is presented

  2. Conjoint-Analyse und Marktsegmentierung

    OpenAIRE

    Steiner, Winfried J.; Baumgartner, Bernhard

    2003-01-01

    Die Marktsegmentierung zählt neben der Neuproduktplanung und Preisgestaltung zu den wesentlichen Einsatzgebieten der Conjoint-Analyse. Neben traditionell eingesetzten zweistufigen Vorgehensweisen, bei denen Conjoint-Analyse und Segmentierung in zwei getrennten Schritten erfolgen, stehen heute mit Methoden wie der Clusterwise Regression oder Mixture-Modellen neuere Entwicklungen, die eine simultane Segmentierung und Präferenzschätzung ermöglichen, zur Verfügung. Der Beitrag gibt einen Überblic...

  3. Henig Proper Efficient Points and Generalized Henig Proper Efficient Points

    Institute of Scientific and Technical Information of China (English)

    Jing Hui QIU

    2009-01-01

    Applying the theory of locally convex spaces to vector optimization,we investigate the relationship between Henig proper efficient points and generalized Henig proper efficient points. In particular,we obtain a sufficient and necessary condition for generalized Henig proper efficient points to be Henig proper efficient points. From this,we derive several convenient criteria for judging Henig proper efficient points.

  4. PynPoint Code for Exoplanet Imaging

    CERN Document Server

    Amara, Adam; Akeret, Joel

    2014-01-01

    We announce the public release of PynPoint, a Python package that we have developed for analysing exoplanet data taken with the angular differential imaging observing technique. In particular, PynPoint is designed to model the point spread function of the central star and to subtract its flux contribution to reveal nearby faint companion planets. The current version of the package does this correction by using a principal component analysis method to build a basis set for modelling the point spread function of the observations. We demonstrate the performance of the package by reanalysing publicly available data on the exoplanet beta Pictoris b, which consists of close to 24,000 individual image frames. We show that PynPoint is able to analyse this typical data in roughly 1.5 minutes on a Mac Pro, when the number of images is reduced by co-adding in sets of 5. The main computational work parallelises well as a result of a reliance on SciPy and NumPy functions. For this calculation the peak memory load is 6Gb, ...

  5. Music analysis and point-set compression

    DEFF Research Database (Denmark)

    Meredith, David

    by the shortest possible descriptions of the piece. With this in mind, two compression algorithms are presented, COSIATEC and SIATECCompress. Each of these algorithms takes as input an in extenso description of a piece of music as a set of points in pitch-time space representing notes. Each algorithm...... then losslessly compresses this set of points, producing an encoding in terms of a sequence of sets of translationally related patterns. The patterns found by the algorithms often correspond closely to those identified by music analysts as being structurally important. The analyses generated by the algorithms...

  6. Properties of residuals for spatial point processes

    DEFF Research Database (Denmark)

    Baddeley, A.; Møller, Jesper; Pakes, A. G.

    2008-01-01

    For any point process in Rd that has a Papangelou conditional intensity λ, we define a random measure of ‘innovations' which has mean zero. When the point process model parameters are estimated from data, there is an analogous random measure of ‘residuals'. We analyse properties of the innovations...... and residuals, including first and second moments, conditional independence, a martingale property, and lack of correlation. Some large sample asymptotics are studied. We derive the marginal distribution of smoothed residuals by solving a distributional equivalence....

  7. Reliability Analyses of Groundwater Pollutant Transport

    Energy Technology Data Exchange (ETDEWEB)

    Dimakis, Panagiotis

    1997-12-31

    This thesis develops a probabilistic finite element model for the analysis of groundwater pollution problems. Two computer codes were developed, (1) one using finite element technique to solve the two-dimensional steady state equations of groundwater flow and pollution transport, and (2) a first order reliability method code that can do a probabilistic analysis of any given analytical or numerical equation. The two codes were connected into one model, PAGAP (Probability Analysis of Groundwater And Pollution). PAGAP can be used to obtain (1) the probability that the concentration at a given point at a given time will exceed a specified value, (2) the probability that the maximum concentration at a given point will exceed a specified value and (3) the probability that the residence time at a given point will exceed a specified period. PAGAP could be used as a tool for assessment purposes and risk analyses, for instance the assessment of the efficiency of a proposed remediation technique or to study the effects of parameter distribution for a given problem (sensitivity study). The model has been applied to study the greatest self sustained, precipitation controlled aquifer in North Europe, which underlies Oslo`s new major airport. 92 refs., 187 figs., 26 tabs.

  8. The quantum change point

    CERN Document Server

    Sentís, Gael; Calsamiglia, John; Chiribella, Giulio; Munoz-Tapia, Ramon

    2016-01-01

    Sudden changes are ubiquitous in nature. Identifying them is of crucial importance for a number of applications in medicine, biology, geophysics, and social sciences. Here we investigate the problem in the quantum domain, considering a source that emits particles in a default state, until a point where it switches to another state. Given a sequence of particles emitted by the source, the problem is to find out where the change occurred. For large sequences, we obtain an analytical expression for the maximum probability of correctly identifying the change point when joint measurements on the whole sequence are allowed. We also construct strategies that measure the particles individually and provide an online answer as soon as a new particle is emitted by the source. We show that these strategies substantially underperform the optimal strategy, indicating that quantum sudden changes, although happening locally, are better detected globally.

  9. Building Points - MO 2012 Stoddard Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Missouri Structure Points are structure points generated from a two pass look over the 2007 State 2ft imagery. Unlike the structure footprints, the building point...

  10. Building Points - MO 2012 Mississippi Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Missouri Structure Points are structure points generated from a two pass look over the 2007 State 2ft imagery. Unlike the structure footprints, the building point...

  11. Building Points - MO 2012 Scott Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Missouri Structure Points are structure points generated from a two pass look over the 2007 State 2ft imagery. Unlike the structure footprints, the building point...

  12. Building Points - MO 2012 Dunklin Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Missouri Structure Points are structure points generated from a two pass look over the 2007 State 2ft imagery. Unlike the structure footprints, the building point...

  13. Building Points - MO 2012 Pemiscot Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Missouri Structure Points are structure points generated from a two pass look over the 2007 State 2ft imagery. Unlike the structure footprints, the building point...

  14. Building Points - MO 2012 New Madrid Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Missouri Structure Points are structure points generated from a two pass look over the 2007 State 2ft imagery. Unlike the structure footprints, the building point...

  15. Mitogenomic analyses from ancient DNA

    DEFF Research Database (Denmark)

    Paijmans, Johanna L.A.; Gilbert, M Thomas P; Hofreiter, Michael

    2013-01-01

    analyses (whether using modern or ancient DNA) were largely restricted to the analysis of short fragments of the mitochondrial genome. However, due to many technological advances during the past decade, a growing number of studies have explored the power of complete mitochondrial genome sequences...... (mitogenomes). Such studies were initially limited to analyses of extant organisms, but developments in both DNA sequencing technologies and general methodological aspects related to working with degraded DNA have resulted in complete mitogenomes becoming increasingly popular for ancient DNA studies as well....... To date, at least 124 partially or fully assembled mitogenomes from more than 20 species have been obtained, and, given the rapid progress in sequencing technology, this number is likely to dramatically increase in the future. The increased information content offered by analysing full mitogenomes has...

  16. Tipping point analysis of atmospheric oxygen concentration

    Energy Technology Data Exchange (ETDEWEB)

    Livina, V. N.; Forbes, A. B. [National Physical Laboratory, Teddington TW11 0LW (United Kingdom); Vaz Martins, T. M. [John Innes Centre, Norwich NR4 7UH (United Kingdom)

    2015-03-15

    We apply tipping point analysis to nine observational oxygen concentration records around the globe, analyse their dynamics and perform projections under possible future scenarios, leading to oxygen deficiency in the atmosphere. The analysis is based on statistical physics framework with stochastic modelling, where we represent the observed data as a composition of deterministic and stochastic components estimated from the observed data using Bayesian and wavelet techniques.

  17. Time Stamps for Fixed-Point Approximation

    DEFF Research Database (Denmark)

    Damian, Daniela

    2001-01-01

    Time stamps were introduced in Shivers's PhD thesis for approximating the result of a control-flow analysis. We show them to be suitable for computing program analyses where the space of results (e.g., control-flow graphs) is large. We formalize time-stamping as a top-down, fixed......-point approximation algorithm which maintains a single copy of intermediate results. We then prove the correctness of this algorithm....

  18. An extensible analysable system model

    DEFF Research Database (Denmark)

    Probst, Christian W.; Hansen, Rene Rydhof

    2008-01-01

    , this does not hold for real physical systems. Approaches such as threat modelling try to target the formalisation of the real-world domain, but still are far from the rigid techniques available in security research. Many currently available approaches to assurance of critical infrastructure security......Analysing real-world systems for vulnerabilities with respect to security and safety threats is a difficult undertaking, not least due to a lack of availability of formalisations for those systems. While both formalisations and analyses can be found for artificial systems such as software...

  19. Point defects in silicates

    International Nuclear Information System (INIS)

    Topaz is a wide band gap insulating crystal with four Al2F2SiO4 formula units per orthorhombic unit cell and containing isolated SiO4 tetrahedron. Electron spin resonance (ESR), UV-VIS spectrophotometry, photoluminescence, and isochronal annealing were used to study the point defects introduced by fast-neutron bombardment or by alpha decay recoils. The superoxide radical is characterized by a single hole-like spin 1/2 signal with principle g-values gxx = 2.0055, gzz = 2.0407 and the major axis of the defect points along 0.356a + 0.152b + 0.922c. The superoxide anneals near 650C. Two polarization dependent absorptions occur in the UV due to the transitions 2IIg → 2IIu and 2IIg → 2Δu. The former has an oscillator strength of 0.06. The 2.5 eV polarization dependent luminescence is due to the transition 2IIg → 2IIu. The 2Δu → 2IIu is non-radiative. The doubly occupied dangling silicon bond, the blue center, is characterized by a 2 eV polarization dependent absorption and is non-paramagnetic. The transition dipole for this absorption points in the direction 0.93a + 0.210b + 0.305c and the oscillator strength is approximately 2.0 x 10-3. The blue center anneals at 500C. This dangling bond defect is one of two models proposed for a similar 2 eV absorption in silica glass. The defects in quartz (SiO2) were introduced by the recoil nuclei after alpha decays of uranium, thorium, and their daughters in natural abundances. The accumulating damage provides a geological clock by which the age of the quartz can be found. The sample came from Yucca Flats, Nevada, the proposed site of a nuclear waste dump

  20. Exploring Foundation Concepts in Introductory Statistics Using Dynamic Data Points

    Science.gov (United States)

    Ekol, George

    2015-01-01

    This paper analyses introductory statistics students' verbal and gestural expressions as they interacted with a dynamic sketch (DS) designed using "Sketchpad" software. The DS involved numeric data points built on the number line whose values changed as the points were dragged along the number line. The study is framed on aggregate…

  1. Ubiquitous Pointing and Drawing

    Directory of Open Access Journals (Sweden)

    Kristian Jantz

    2007-12-01

    Full Text Available This paper presents a system that enables a presenter to work directly on the projection without the typical interruption of the presentation flow being caused by a mouse or keyboard activity. The lecturer simply uses his fingers as a natural and intuitive pointing device. The system consists of an LED, a standard webcam, a video projector, and a small software system running on a notebook computer. The camera is positioned such that it views the projection area. After a few calibration clicks, the mouse emulation is functional at any place of the projection area.

  2. Descriptive Analyses of Mechanical Systems

    DEFF Research Database (Denmark)

    Andreasen, Mogens Myrup; Hansen, Claus Thorp

    2003-01-01

    Forord Produktanalyse og teknologianalyse kan gennmføres med et bredt socio-teknisk sigte med henblik på at forstå kulturelle, sociologiske, designmæssige, forretningsmæssige og mange andre forhold. Et delområde heri er systemisk analyse og beskrivelse af produkter og systemer. Nærværende kompend...

  3. Evaluation "Risk analyses of agroparks"

    NARCIS (Netherlands)

    Ge, L.

    2011-01-01

    Dit TransForum project richt zich op analyse van de onzekerheden en mogelijkheden van agroparken. Dit heeft geleid tot een risicomodel dat de kwalitatieve en/of kwantitatieve onzekerheden van een agropark project in kaart brengt. Daarmee kunnen maatregelen en managementstrategiën worden geïdentifice

  4. The Tipping Points of Technology Development

    Directory of Open Access Journals (Sweden)

    Tauno Kekäle

    2014-07-01

    Full Text Available The tipping point, the decisive point in time in the competition between old and new, is an interesting phenomenon in physics of today. This aspect in technology acceptance is connected to many business decisions such as technology investments, product releases, resource allocation, sales forecasts and, ultimately, affects the profitability and even survival of a company. The tipping point itself is based on many stochastic and dynamic variables, and the process may at least partly be described as path-dependent. This paper analyses the tipping point from three aspects: (1 product performance, (2 features of the market and infrastructure (including related technologies and human network externalities, and (3 actions of the incumbents (including customer lock-in, systems lock-in, and sustaining innovation. The paper is based on the Bass s-curve idea and the technology trajectory concept proposed by Dosi. Three illustrative cases are presented to make the point of the multiple factors affecting technology acceptance and, thus, the tipping point. The paper also suggests outlines for further research in field of computer simulation.

  5. Modeling fixation locations using spatial point processes.

    Science.gov (United States)

    Barthelmé, Simon; Trukenbrod, Hans; Engbert, Ralf; Wichmann, Felix

    2013-10-01

    Whenever eye movements are measured, a central part of the analysis has to do with where subjects fixate and why they fixated where they fixated. To a first approximation, a set of fixations can be viewed as a set of points in space; this implies that fixations are spatial data and that the analysis of fixation locations can be beneficially thought of as a spatial statistics problem. We argue that thinking of fixation locations as arising from point processes is a very fruitful framework for eye-movement data, helping turn qualitative questions into quantitative ones. We provide a tutorial introduction to some of the main ideas of the field of spatial statistics, focusing especially on spatial Poisson processes. We show how point processes help relate image properties to fixation locations. In particular we show how point processes naturally express the idea that image features' predictability for fixations may vary from one image to another. We review other methods of analysis used in the literature, show how they relate to point process theory, and argue that thinking in terms of point processes substantially extends the range of analyses that can be performed and clarify their interpretation.

  6. Holographic Three point Functions

    DEFF Research Database (Denmark)

    Martirosyan, Ara

    . In the spirit of understanding this problem better, the thesis discusses the divergences appearing in the calculation of structure constants involving two giant and one point-like gravitons in the string theories on AdS_5 x S^5 and AdS_4 x S^7/Z_k backgrounds. Coherent state approach for the tree......The main subject of this thesis is the computation of structure constants appearing in the three-point functions for certain type of states/operators in the context of the AdS/CFT correspondence, which is one of the important parts of the dynamical problem in the dual theories of the correspondence......-level calculation of structure constants for heavy-heavy-light operators in the SU(2) x SU(2) sector of the ABJM theory is carried out both on weak and strong coupling sides of the theory. Another remarkable determinant-result is obtained in the same sector of ABJM theory using integrability techniques...

  7. SPIRE Point Source Photometry

    CERN Document Server

    Pearson, Chris; North, Chris; Bendo, George; Conversi, Luca; Dowell, Darren; Griffin, Matt; Jin, Terry; Laporte, Nicolas; Papageorgiou, Andreas; Schulz, Bernhard; Shupe, Dave; Smith, Anthony J; Xu, Kevin

    2014-01-01

    The different algorithms appropriate for point source photometry on data from the SPIRE instrument on-board the Herschel Space Observatory, within the Herschel Interactive Processing Environment (HIPE) are compared. Point source photometry of a large ensemble of standard calibration stars and dark sky observations is carried out using the 4 major methods within HIPE: SUSSEXtractor, DAOphot, the SPIRE Timeline Fitter and simple Aperture Photometry. Colour corrections and effective beam areas as a function of the assumed source spectral index are also included to produce a large number of photometric measurements per individual target, in each of the 3 SPIRE bands (250, 350, 500um), to examine both the accuracy and repeatability of each of the 4 algorithms. It is concluded that for flux densities down to the level of 30mJy that the SPIRE Timeline Fitter is the method of choice. However, at least in the 250 and 350um bands, all 4 methods provide photometric repeatability better than a few percent down to at appr...

  8. Selective Integration in the Material-Point Method

    DEFF Research Database (Denmark)

    Andersen, Lars; Andersen, Søren; Damkilde, Lars

    2009-01-01

    The paper deals with stress integration in the material-point method. In order to avoid parasitic shear in bending, a formulation is proposed, based on selective integration in the background grid that is used to solve the governing equations. The suggested integration scheme is compared...... to a traditional material-point-method computation in which the stresses are evaluated at the material points. The deformation of a cantilever beam is analysed, assuming elastic or elastoplastic material behaviour....

  9. A Web-based Tool Combining Different Type Analyses

    DEFF Research Database (Denmark)

    Henriksen, Kim Steen; Gallagher, John Patrick

    2006-01-01

    of both, and they can be goal-dependent or goal-independent. We describe a prototype tool that can be accessed from a web browser, allowing various type analyses to be run. The first goal of the tool is to allow the analysis results to be examined conveniently by clicking on points in the original program...

  10. Point Source Extraction with MOPEX

    CERN Document Server

    Marleau, D M F R

    2005-01-01

    MOPEX (MOsaicking and Point source EXtraction) is a package developed at the Spitzer Science Center for astronomical image processing. We report on the point source extraction capabilities of MOPEX. Point source extraction is implemented as a two step process: point source detection and profile fitting. Non-linear matched filtering of input images can be performed optionally to increase the signal-to-noise ratio and improve detection of faint point sources. Point Response Function (PRF) fitting of point sources produces the final point source list which includes the fluxes and improved positions of the point sources, along with other parameters characterizing the fit. Passive and active deblending allows for successful fitting of confused point sources. Aperture photometry can also be computed for every extracted point source for an unlimited number of aperture sizes. PRF is estimated directly from the input images. Implementation of efficient methods of background and noise estimation, and modified Simplex a...

  11. May 2002 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs) from Dana Point to Point...

  12. September 2002 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs) from Dana Point to Point...

  13. Repelling Point Bosons

    Science.gov (United States)

    McGuire, J. B.

    2011-12-01

    There is a body of conventional wisdom that holds that a solvable quantum problem, by virtue of its solvability, is pathological and thus irrelevant. It has been difficult to refute this view owing to the paucity of theoretical constructs and experimental results. Recent experiments involving equivalent ions trapped in a spatial conformation of extreme anisotropic confinement (longitudinal extension tens, hundreds or even thousands of times transverse extension) have modified the view of relevancy, and it is now possible to consider systems previously thought pathological, in particular point Bosons that repel in one dimension. It has been difficult for the experimentalists to utilize existing theory, mainly due to long-standing theoretical misunderstanding of the relevance of the permutation group, in particular the non-commutativity of translations (periodicity) and transpositions (permutation). This misunderstanding is most easily rectified in the case of repelling Bosons.

  14. The Point Mass Concept

    Directory of Open Access Journals (Sweden)

    Lehnert B.

    2011-04-01

    Full Text Available A point-mass concept has been elaborated from the equations of the gravitational field. One application of these deductions results in a black hole configuration of the Schwarzschild type, having no electric charge and no angular momentum. The critical mass of a gravitational collapse with respect to the nuclear binding energy is found to be in the range of 0.4 to 90 solar masses. A second application is connected with the spec- ulation about an extended symmetric law of gravitation, based on the options of positive and negative mass for a particle at given positive energy. This would make masses of equal polarity attract each other, while masses of opposite polarity repel each other. Matter and antimatter are further proposed to be associated with the states of positive and negative mass. Under fully symmetric conditions this could provide a mechanism for the separation of antimatter from matter at an early stage of the universe.

  15. Critical Points of Contact

    DEFF Research Database (Denmark)

    Jensen, Ole B.; Morelli, Nicola

    2011-01-01

    In contemporary urban societies multiple networks and systems interact, overlap, exist in parallel, converge, conflict etc. creating unforeseen complexity and less transparency. By exploring how layered networks of physical movement, service information, goods delivery, commercial communication etc....... are connected (and disconnected) we get a much better understanding of how to design and intervene regardless if we are thinking about public spaces in the city or new systems of service design. The many networks orchestrating and facilitating contemporary everyday life are dependent on the strategic sites...... where the networks meet and establish contact. Thus we argue for the usefulness of the notion of Critical Point of Contact (CPC) to deepen our understanding of the actual life within networks. En route to this notion we draw upon theories within as diverse realms such as interaction design, service...

  16. Latent myofascial trigger points.

    Science.gov (United States)

    Ge, Hong-You; Arendt-Nielsen, Lars

    2011-10-01

    A latent myofascial trigger point (MTP) is defined as a focus of hyperirritability in a muscle taut band that is clinically associated with local twitch response and tenderness and/or referred pain upon manual examination. Current evidence suggests that the temporal profile of the spontaneous electrical activity at an MTP is similar to focal muscle fiber contraction and/or muscle cramp potentials, which contribute significantly to the induction of local tenderness and pain and motor dysfunctions. This review highlights the potential mechanisms underlying the sensory-motor dysfunctions associated with latent MTPs and discusses the contribution of central sensitization associated with latent MTPs and the MTP network to the spatial propagation of pain and motor dysfunctions. Treating latent MTPs in patients with musculoskeletal pain may not only decrease pain sensitivity and improve motor functions, but also prevent latent MTPs from transforming into active MTPs, and hence, prevent the development of myofascial pain syndrome.

  17. Virtual turning points

    CERN Document Server

    Honda, Naofumi; Takei, Yoshitsugu

    2015-01-01

    The discovery of a virtual turning point truly is a breakthrough in WKB analysis of higher order differential equations. This monograph expounds the core part of its theory together with its application to the analysis of higher order Painlevé equations of the Noumi–Yamada type and to the analysis of non-adiabatic transition probability problems in three levels. As M.V. Fedoryuk once lamented, global asymptotic analysis of higher order differential equations had been thought to be impossible to construct. In 1982, however, H.L. Berk, W.M. Nevins, and K.V. Roberts published a remarkable paper in the Journal of Mathematical Physics indicating that the traditional Stokes geometry cannot globally describe the Stokes phenomena of solutions of higher order equations; a new Stokes curve is necessary.

  18. Learning Determinantal Point Processes

    CERN Document Server

    Kulesza, Alex

    2012-01-01

    Determinantal point processes (DPPs), which arise in random matrix theory and quantum physics, are natural models for subset selection problems where diversity is preferred. Among many remarkable properties, DPPs offer tractable algorithms for exact inference, including computing marginal probabilities and sampling; however, an important open question has been how to learn a DPP from labeled training data. In this paper we propose a natural feature-based parameterization of conditional DPPs, and show how it leads to a convex and efficient learning formulation. We analyze the relationship between our model and binary Markov random fields with repulsive potentials, which are qualitatively similar but computationally intractable. Finally, we apply our approach to the task of extractive summarization, where the goal is to choose a small subset of sentences conveying the most important information from a set of documents. In this task there is a fundamental tradeoff between sentences that are highly relevant to th...

  19. Analysing the distribution of synaptic vesicles using a spatial point process model

    DEFF Research Database (Denmark)

    Khanmohammadi, Mahdieh; Waagepetersen, Rasmus; Nava, Nicoletta;

    2014-01-01

    Stress can affect the brain functionality in many ways. As the synaptic vesicles have a major role in nervous signal transportation in synapses, their distribution in relationship to the active zone is very important in studying the neuron responses. We study the effect of stress on brain...... functionality by statistically modelling the distribution of the synaptic vesicles in two groups of rats: a control group subjected to sham stress and a stressed group subjected to a single acute foot-shock (FS)-stress episode. We hypothesize that the synaptic vesicles have different spatial distributions...

  20. Transcriptome and selected metabolite analyses reveal points of sugar metabolism in jackfruit (Artocarpus heterophyllus Lam.).

    Science.gov (United States)

    Hu, Lisong; Wu, Gang; Hao, Chaoyun; Yu, Huan; Tan, Lehe

    2016-07-01

    Artocarpus heterophyllus Lam., commonly known as jackfruit, produces the largest tree-borne fruit known thus far. The edible part of the fruit develops from the perianths, and contains many sugar-derived compounds. However, its sugar metabolism is poorly understood. A fruit perianth transcriptome was sequenced on an Illumina HiSeq 2500 platform, producing 32,459 unigenes with an average length of 1345nt. Sugar metabolism was characterized by comparing expression patterns of genes related to sugar metabolism and evaluating correlations with enzyme activity and sugar accumulation during fruit perianth development. During early development, high expression levels of acid invertases and corresponding enzyme activities were responsible for the rapid utilization of imported sucrose for fruit growth. The differential expression of starch metabolism-related genes and corresponding enzyme activities were responsible for starch accumulated before fruit ripening but decreased during ripening. Sucrose accumulated during ripening, when the expression levels of genes for sucrose synthesis were elevated and high enzyme activity was observed. The comprehensive transcriptome analysis presents fundamental information on sugar metabolism and will be a useful reference for further research on fruit perianth development in jackfruit. PMID:27181946

  1. Gene network analyses point to the importance of human tissue kallikreins in melanoma progression

    Directory of Open Access Journals (Sweden)

    Landman Gilles

    2011-10-01

    Full Text Available Abstract Background A wide variety of high-throughput microarray platforms have been used to identify molecular targets associated with biological and clinical tumor phenotypes by comparing samples representing distinct pathological states. Methods The gene expression profiles of human cutaneous melanomas were determined by cDNA microarray analysis. Next, a robust analysis to determine functional classifications and make predictions based on data-oriented hypotheses was performed. Relevant networks that may be implicated in melanoma progression were also considered. Results In this study we aimed to analyze coordinated gene expression changes to find molecular pathways involved in melanoma progression. To achieve this goal, ontologically-linked modules with coordinated expression changes in melanoma samples were identified. With this approach, we detected several gene networks related to different modules that were induced or repressed during melanoma progression. Among them we observed high coordinated expression levels of genes involved in a cell communication (KRT4, VWF and COMP; b epidermal development (KLK7, LAMA3 and EVPL; and c functionally related to kallikreins (EVPL, KLK6, KLK7, KLK8, SERPINB13, SERPING1 and SLPI. Our data also indicated that hKLK7 protein expression was significantly associated with good prognosis and survival. Conclusions Our findings, derived from a different type of analysis of microarray data, highlight the importance of analyzing coordinated gene expression to find molecular pathways involved in melanoma progression.

  2. Transcriptome and selected metabolite analyses reveal points of sugar metabolism in jackfruit (Artocarpus heterophyllus Lam.).

    Science.gov (United States)

    Hu, Lisong; Wu, Gang; Hao, Chaoyun; Yu, Huan; Tan, Lehe

    2016-07-01

    Artocarpus heterophyllus Lam., commonly known as jackfruit, produces the largest tree-borne fruit known thus far. The edible part of the fruit develops from the perianths, and contains many sugar-derived compounds. However, its sugar metabolism is poorly understood. A fruit perianth transcriptome was sequenced on an Illumina HiSeq 2500 platform, producing 32,459 unigenes with an average length of 1345nt. Sugar metabolism was characterized by comparing expression patterns of genes related to sugar metabolism and evaluating correlations with enzyme activity and sugar accumulation during fruit perianth development. During early development, high expression levels of acid invertases and corresponding enzyme activities were responsible for the rapid utilization of imported sucrose for fruit growth. The differential expression of starch metabolism-related genes and corresponding enzyme activities were responsible for starch accumulated before fruit ripening but decreased during ripening. Sucrose accumulated during ripening, when the expression levels of genes for sucrose synthesis were elevated and high enzyme activity was observed. The comprehensive transcriptome analysis presents fundamental information on sugar metabolism and will be a useful reference for further research on fruit perianth development in jackfruit.

  3. Analyse du discours et archive

    OpenAIRE

    Maingueneau, Dominique

    2007-01-01

    Les recherches qui se réclament de "l’analyse du discours" connaissent un développement considérable dans le monde entier ; en revanche, "l’école française d’analyse du discours" (AD) traverse une crise d’identité depuis le début des années 80. Dans cet exposé nous voudrions explorer les raisons de cette crise, puis préciser le concept d’archive qui, à notre sens, permet de prolonger la voie ouverte à la fin des années 1960. Mais il ne s’agit que d’une des voies possibles, dès lors que, comme...

  4. Workload analyse of assembling process

    Science.gov (United States)

    Ghenghea, L. D.

    2015-11-01

    The workload is the most important indicator for managers responsible of industrial technological processes no matter if these are automated, mechanized or simply manual in each case, machines or workers will be in the focus of workload measurements. The paper deals with workload analyses made to a most part manual assembling technology for roller bearings assembling process, executed in a big company, with integrated bearings manufacturing processes. In this analyses the delay sample technique have been used to identify and divide all bearing assemblers activities, to get information about time parts from 480 minutes day work time that workers allow to each activity. The developed study shows some ways to increase the process productivity without supplementary investments and also indicated the process automation could be the solution to gain maximum productivity.

  5. Analysing Protocol Stacks for Services

    DEFF Research Database (Denmark)

    Gao, Han; Nielson, Flemming; Nielson, Hanne Riis

    2011-01-01

    We show an approach, CaPiTo, to model service-oriented applications using process algebras such that, on the one hand, we can achieve a certain level of abstraction without being overwhelmed by the underlying implementation details and, on the other hand, we respect the concrete industrial standa...... to the financial case study taken from Chapter 0-3. Finally, we develop a static analysis to analyse the security properties as they emerge at the level of concrete industrial protocols....

  6. Tematisk analyse af amerikansk hiphop

    OpenAIRE

    Tranberg-Hansen, Katrine; Bøgh Larsen, Cecilie; Jeppsson,Louise Emilie; Lindberg Kirkegaard, Nanna; Funch Madsen, Signe; Bülow Bach, Maria

    2013-01-01

    This paper examines the possible development in the function of American hiphop. It focuses on specific themes like ghetto, freedom, rebellion, and racial discrimination in hiphop music. To investigate this possible development two text analysis methods are used: a pragmatic and a stylistic text analysis, and a historical method is used: a source criticism. A minimal amount of literature has been published on how hiphop culture arose. The-­‐ se studies, however, make it possible to analyse...

  7. Tie-points and fixed-points in N^*

    CERN Document Server

    Dow, Alan

    2007-01-01

    A point x is a (bow) tie-point of a space X if X setminus {x} can be partitioned into (relatively) clopen sets each with x in its closure. Tie-points have appeared in the construction of non-trivial autohomeomorphisms of betaN setminus N and in the recent study of (precisely) 2-to-1 maps on betaN setminus N . In these cases the tie-points have been the unique fixed point of an involution on betaN setminus N. This paper is motivated by the search for 2-to-1 maps and obtaining tie-points of strikingly differing characteristics.

  8. Tie-points and fixed-points in N^*

    OpenAIRE

    Dow, Alan; SHELAH, Saharon

    2007-01-01

    A point x is a (bow) tie-point of a space X if X setminus {x} can be partitioned into (relatively) clopen sets each with x in its closure. Tie-points have appeared in the construction of non-trivial autohomeomorphisms of betaN setminus N and in the recent study of (precisely) 2-to-1 maps on betaN setminus N . In these cases the tie-points have been the unique fixed point of an involution on betaN setminus N. This paper is motivated by the search for 2-to-1 maps and obtaining tie-points of str...

  9. Pointing to others: How the target gender influences pointing performance.

    Science.gov (United States)

    Cleret de Langavant, Laurent; Jacquemot, Charlotte; Cruveiller, Virginie; Dupoux, Emmanuel; Bachoud-Lévi, Anne-Catherine

    2016-01-01

    Pointing is a communicative gesture that allows individuals to share information about surrounding objects with other humans. Patients with heterotopagnosia are specifically impaired in pointing to other humans' body parts but not in pointing to themselves or to objects. Here, we describe a female patient with heterotopagnosia who was more accurate in pointing to men's body parts than to women's body parts. We replicated this gender effect in healthy participants with faster reaction times for pointing to men's body parts than to women's body parts. We discuss the role of gender stereotypes in explaining why it is more difficult to point to women than to men. PMID:27593456

  10. ATLAS Point 1 Construction

    CERN Multimedia

    Inigo-Golfin, J

    After 3 years of work in point 1, a number of surface buildings have already been completed and handed over to CERN (the control, the gas and the cooling and ventilation buildings) and, probably more appealing to the public, 60,000 m3 of earth have already been excavated from underground. At present, the technical cavern USA15 and its access shaft are almost finished, leaving only the main cavern and the liaison galleries to be completed in the coming year and a half. The main cavern has been excavated down to the radiation limit and its walls and vault will presently be concreted (see below the picture of the section of the vault with the impressive shell of 1.2 m thickness). The excavation of the bench (27 vertical metres to go yet!) will proceed from August, when some additional civil engineering work in the LHC tunnel will be undertaken. Needless to say many different services are necessary around the detector, both for its installation and future operation for physics. To that end much of the heavy...

  11. "Point de suspension"

    CERN Multimedia

    2004-01-01

    CERN - Globe of Science and Innovation 20 and 21 October Acrobatics, mime, a cappella singing, projections of images, a magical setting... a host of different tools of a grandeur matching that of the Universe they relate. A camera makes a massive zoom out to reveal the multiple dimensions of Nature. Freeze the frame: half way between the infinitesimally small and the infinitesimally large, a man suspends his everyday life (hence the title "Point de Suspension", which refers to the three dots at the end of an uncompleted sentence) to take a glimpse of the place he occupies in the great history of the Universe. An unusual perspective on what it means to be a human being... This wondrous show in the Globe of Science and Innovation, specially created by the Miméscope* company for the official ceremony marking CERN's fiftieth anniversary, is a gift from the Government of the Republic and Canton of Geneva, which also wishes to share this moment of wonder with the local population. There will be three perfo...

  12. "Point de suspension"

    CERN Multimedia

    2004-01-01

    http://www.cern.ch/cern50/ CERN - Globe of Science and Innovation 20 and 21 October Acrobatics, mime, a cappella singing, projections of images, a magical setting... a host of different tools of a grandeur matching that of the Universe they relate. A camera makes a massive zoom out to reveal the multiple dimensions of Nature. Freeze the frame: half way between the infinitesimally small and the infinitesimally large, a man suspends his everyday life (hence the title "Point de Suspension", which refers to the three dots at the end of an uncompleted sentence) to take a glimpse of the place he occupies in the great history of the Universe. An unusual perspective on what it means to be a human being... This wondrous show in the Globe of Science and Innovation, specially created by the Miméscope* company for the official ceremony marking CERN's fiftieth anniversary, is a gift from the Government of the Republic and Canton of Geneva, which also wishes to share this moment of wonder with the local pop...

  13. "Point de suspension"

    CERN Multimedia

    2004-01-01

    CERN - Globe of Science and Innovation 20 and 21 October Acrobatics, mime, a cappella singing, projections of images, a magical setting... a host of different tools of a grandeur matching that of the Universe they relate. A camera makes a massive zoom out to reveal the multiple dimensions of Nature. Freeze the frame: half way between the infinitesimally small and the infinitesimally large, a man suspends his everyday life (hence the title "Point de Suspension", which refers to the three dots at the end of an uncompleted sentence) to take a glimpse of the place he occupies in the great history of the Universe. An unusual perspective on what it means to be a human being... This spectacle in the Globe of Science and Innovation, specially created by the Miméscope* company for the official ceremony marking CERN's fiftieth anniversary, is a gift from the Government of the Republic and Canton of Geneva, which also wishes to share this moment of wonder with the local population. There will be three performances for...

  14. Point 1 Updates

    CERN Multimedia

    Inigo-Golfin, J.

    The ATLAS experimental area is located in Point 1, just across the main CERN entrance, in the commune of Meyrin. There people are ever so busy to finish the different infrastructures for ATLAS. Not only has Civil Engineering finished the construction of the USA15 technical cavern, but the excavation of the main UX15 cavern has resumed below the machine tunnel, after a brief halt to allow the construction of the UJ-caverns for the power converters of the LHC machine. The excavation work should end in August 2002. The UX15 hand-over to ATLAS is expected in April 2003. On the surface civil engineering is starting to complete the last two surface buildings (SDX1 and SH1), once the services (cooling pipes, ventilation ducts and the largest item, the lift modules and its lift of course) in the shaft PX15 have been completed. But the civil engineering is not all. A lot more is under way. The site installation of the steel structures in the caverns is to begin in Autumn, along with all the cooling pipes, airconditi...

  15. Function Point Analysis Depot

    Science.gov (United States)

    Muniz, R.; Martinez, El; Szafran, J.; Dalton, A.

    2011-01-01

    The Function Point Analysis (FPA) Depot is a web application originally designed by one of the NE-C3 branch's engineers, Jamie Szafran, and created specifically for the Software Development team of the Launch Control Systems (LCS) project. The application consists of evaluating the work of each developer to be able to get a real estimate of the hours that is going to be assigned to a specific task of development. The Architect Team had made design change requests for the depot to change the schema of the application's information; that information, changed in the database, needed to be changed in the graphical user interface (GUI) (written in Ruby on Rails (RoR and the web service/server side in Java to match the database changes. These changes were made by two interns from NE-C, Ricardo Muniz from NE-C3, who made all the schema changes for the GUI in RoR and Edwin Martinez, from NE-C2, who made all the changes in the Java side.

  16. Einige Bemerkungen zur Bedeutung von "stoffdidaktischen" Aspekten am Beispiel der Analyse eines Unterrichtsausschnitts in der Arbeit von J. Voigt

    OpenAIRE

    Blum, Werner

    1985-01-01

    By example of an excerpt of a lesson analysed by J. voigt we want to point to the importance of didactic aspects related to topics ("stoffdidaktisehe" Aspekte) in analysing, planning and performing mathematics education.

  17. Analyses of a Virtual World

    CERN Document Server

    Holovatch, Yurij; Szell, Michael; Thurner, Stefan

    2016-01-01

    We present an overview of a series of results obtained from the analysis of human behavior in a virtual environment. We focus on the massive multiplayer online game (MMOG) Pardus which has a worldwide participant base of more than 400,000 registered players. We provide evidence for striking statistical similarities between social structures and human-action dynamics in the real and virtual worlds. In this sense MMOGs provide an extraordinary way for accurate and falsifiable studies of social phenomena. We further discuss possibilities to apply methods and concepts developed in the course of these studies to analyse oral and written narratives.

  18. THOR Turbulence Electron Analyser: TEA

    Science.gov (United States)

    Fazakerley, Andrew; Moore, Tom; Owen, Chris; Pollock, Craig; Wicks, Rob; Samara, Marilia; Rae, Jonny; Hancock, Barry; Kataria, Dhiren; Rust, Duncan

    2016-04-01

    Turbulence Heating ObserveR (THOR) is the first mission ever flown in space dedicated to plasma turbulence. The Turbulence Electron Analyser (TEA) will measure the plasma electron populations in the mission's Regions of Interest. It will collect a 3D electron velocity distribution with cadences as short as 5 ms. The instrument will be capable of measuring energies up to 30 keV. TEA consists of multiple electrostatic analyser heads arranged so as to measure electrons arriving from look directions covering the full sky, i.e. 4 pi solid angle. The baseline concept is similar to the successful FPI-DES instrument currently operating on the MMS mission. TEA is intended to have a similar angular resolution, but a larger geometric factor. In comparison to earlier missions, TEA improves on the measurement cadence. For example, MMS FPI-DES routinely operates at 30 ms cadence. The objective of measuring distributions at rates as fast as 5 ms is driven by the mission's scientific requirements to resolve electron gyroscale size structures, where plasma heating and fluctuation dissipation is predicted to occur. TEA will therefore be capable of making measurements of the evolution of distribution functions across thin (a few km) current sheets travelling past the spacecraft at up to 600 km/s, of the Power Spectral Density of fluctuations of electron moments and of distributions fast enough to match frequencies with waves expected to be dissipating turbulence (e.g. with 100 Hz whistler waves).

  19. Clinical Application of Point Diji

    Institute of Scientific and Technical Information of China (English)

    栾继萍

    2004-01-01

    @@ Diji (SP 8) is a cleft point of the Spleen Channel of Foot-Taiyang. Its indications include abdominal pain, diarrhea, edema, dysmenorrhea and certain other symptoms caused by incoordination between the liver and the spleen. Either taking the point alone or together with some other adjunct points in clinical practice, the author has obtained satisfactory curative effects.

  20. Dynamic Virtual Join Point Dispatch

    NARCIS (Netherlands)

    Bockisch, Christoph; Hauptmann, Michael; Mezini, Mira

    2006-01-01

    Conceptually, join points are points in the execution of a program and advice is late-bound to them. We propose the notion of virtual join points that makes this concept explicit not only at a conceptual, but also at implementation level. In current implementations of aspect-oriented languages, bind

  1. Solving discrete zero point problems

    NARCIS (Netherlands)

    van der Laan, G.; Talman, A.J.J.; Yang, Z.F.

    2004-01-01

    In this paper an algorithm is proposed to .nd a discrete zero point of a function on the collection of integral points in the n-dimensional Euclidean space IRn.Starting with a given integral point, the algorithm generates a .nite sequence of adjacent integral simplices of varying dimension and termi

  2. Magic Pointing for Eyewear Computers

    DEFF Research Database (Denmark)

    Jalaliniya, Shahram; Mardanbegi, Diako; Pederson, Thomas

    2015-01-01

    In this paper, we propose a combination of head and eye movements for touchlessly controlling the "mouse pointer" on eyewear devices, exploiting the speed of eye pointing and accuracy of head pointing. The method is a wearable computer-targeted variation of the original MAGIC pointing approach...

  3. Analysing performance through value creation

    Directory of Open Access Journals (Sweden)

    Adrian TRIFAN

    2015-12-01

    Full Text Available This paper draws a parallel between measuring financial performance in 2 variants: the first one using data offered by accounting, which lays emphasis on maximizing profit, and the second one which aims to create value. The traditional approach to performance is based on some indicators from accounting data: ROI, ROE, EPS. The traditional management, based on analysing the data from accounting, has shown its limits, and a new approach is needed, based on creating value. The evaluation of value based performance tries to avoid the errors due to accounting data, by using other specific indicators: EVA, MVA, TSR, CVA. The main objective is shifted from maximizing the income to maximizing the value created for shareholders. The theoretical part is accompanied by a practical analysis regarding the creation of value and an analysis of the main indicators which evaluate this concept.

  4. Economical analyses in interventional radiology

    International Nuclear Information System (INIS)

    Considerations about the relation between benefit and expenses are also gaining increasing importance in interventional radiology. This review aims at providing a survey about the published data concerning economical analyses of some of the more frequently employed interventions in radiology excluding neuroradiological and coronary interventions. Because of the relative scarcity of literature in this field, all identified articles (n=46) were included without selection for methodological quality. For a number of radiological interventions the cost-effectiveness has already been demonstrated, e.g., PTA of femoropopliteal and iliac artery stenoses, stenting of renal artery stenoses, placement of vena-cava filters, as well as metal stents in malignant biliary and esophageal obstructions. Conflicting data exist for the treatment of abdominal aortic aneurysms. So far, no analysis could be found that directly compares bypass surgery versus PTA+stent in iliac arteries. (orig.)

  5. HGCal Simulation Analyses for CMS

    CERN Document Server

    Bruno, Sarah Marie

    2015-01-01

    This summer, I approached the topic of fast-timing detection of photons from Higgs decays via simulation analyses, working under the supervision of Dr. Adolf Bornheim of the California Institute of Technology. My specific project focused on simulating the high granularity calorimeter for the Compact Muon Solenoid (CMS) experiment. CMS detects particles using calorimeters. The Electromagnetic Calorimeter (ECal) is arranged cylindrically to form a barrel section and two “endcaps.” Previously, both the barrel and endcap have employed lead tungstate crystal detectors, known as the “shashlik” design. The crystal detectors, however, rapidly degrade from exposure to radiation. This effect is most pronounced in the endcaps. To avoid the high expense of frequently replacing degraded detectors, it was recently decided to eliminate the endcap crystals in favor of an arrangement of silicon detectors known as the “High Granularity Calorimeter” (HGCal), while leaving the barrel detector technology unchanged. T...

  6. Analyse des besoins des usagers

    OpenAIRE

    KHOUDOUR,L; LANGLAIS,A; Charpentier, C.; MOTTE,C; PIAN,C

    2002-01-01

    Il s'agit d'étendre la surveillance vidéo de l'enceinte du métro vers l'intérieur des rames. Les images captées constituent des prises de vue des événements qui se déroulent à l'intérieur des véhicules afin notamment d'améliorer la sécurité des usagers transportes. Il est possible de mémoriser les images des quelques instants précédant un incident usager, d'analyser ces images en temps différé et de mieux appréhender en temps réel le comportement des usagers face à des événements ou des consi...

  7. Uncertainty and Sensitivity Analyses Plan

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, J.C.; Ramsdell, J.V. Jr.

    1993-04-01

    Hanford Environmental Dose Reconstruction (HEDR) Project staff are developing mathematical models to be used to estimate the radiation dose that individuals may have received as a result of emissions since 1944 from the US Department of Energy's (DOE) Hanford Site near Richland, Washington. An uncertainty and sensitivity analyses plan is essential to understand and interpret the predictions from these mathematical models. This is especially true in the case of the HEDR models where the values of many parameters are unknown. This plan gives a thorough documentation of the uncertainty and hierarchical sensitivity analysis methods recommended for use on all HEDR mathematical models. The documentation includes both technical definitions and examples. In addition, an extensive demonstration of the uncertainty and sensitivity analysis process is provided using actual results from the Hanford Environmental Dose Reconstruction Integrated Codes (HEDRIC). This demonstration shows how the approaches used in the recommended plan can be adapted for all dose predictions in the HEDR Project.

  8. Uncertainty and Sensitivity Analyses Plan

    International Nuclear Information System (INIS)

    Hanford Environmental Dose Reconstruction (HEDR) Project staff are developing mathematical models to be used to estimate the radiation dose that individuals may have received as a result of emissions since 1944 from the US Department of Energy's (DOE) Hanford Site near Richland, Washington. An uncertainty and sensitivity analyses plan is essential to understand and interpret the predictions from these mathematical models. This is especially true in the case of the HEDR models where the values of many parameters are unknown. This plan gives a thorough documentation of the uncertainty and hierarchical sensitivity analysis methods recommended for use on all HEDR mathematical models. The documentation includes both technical definitions and examples. In addition, an extensive demonstration of the uncertainty and sensitivity analysis process is provided using actual results from the Hanford Environmental Dose Reconstruction Integrated Codes (HEDRIC). This demonstration shows how the approaches used in the recommended plan can be adapted for all dose predictions in the HEDR Project

  9. Isotopic signatures by bulk analyses

    International Nuclear Information System (INIS)

    Los Alamos National Laboratory has developed a series of measurement techniques for identification of nuclear signatures by analyzing bulk samples. Two specific applications for isotopic fingerprinting to identify the origin of anthropogenic radioactivity in bulk samples are presented. The first example is the analyses of environmental samples collected in the US Arctic to determine the impact of dumping of radionuclides in this polar region. Analyses of sediment and biota samples indicate that for the areas sampled the anthropogenic radionuclide content of sediments was predominantly the result of the deposition of global fallout. The anthropogenic radionuclide concentrations in fish, birds and mammals were very low. It can be surmised that marine food chains are presently not significantly affected. The second example is isotopic fingerprinting of water and sediment samples from the Rocky Flats Facility (RFP). The largest source of anthropogenic radioactivity presently affecting surface-waters at RFP is the sediments that are currently residing in the holding ponds. One gram of sediment from a holding pond contains approximately 50 times more plutonium than 1 liter of water from the pond. Essentially 100% of the uranium in Ponds A-1 and A-2 originated as depleted uranium. The largest source of radioactivity in the terminal Ponds A-4, B-5 and C-2 was naturally occurring uranium and its decay product radium. The uranium concentrations in the waters collected from the terminal ponds contained 0.05% or less of the interim standard calculated derived concentration guide for uranium in waters available to the public. All of the radioactivity observed in soil, sediment and water samples collected at RFP was naturally occurring, the result of processes at RFP or the result of global fallout. No extraneous anthropogenic alpha, beta or gamma activities were detected. The plutonium concentrations in Pond C-2 appear to vary seasonally

  10. Precision pointing and tracking system /PPTS/

    Science.gov (United States)

    Brown, T. K.; Leblanc, D. R.; Mettler, E.; Gaalema, S. D.

    1978-01-01

    As part of its advanced development work, JPL is developing a Precision Pointing and Tracking System (PPTS) for science platform control on unmanned planetary spacecraft. The PPTS will extend science capabilities on future missions by providing highly accurate (10 arcsec) and stable (0.2 arcsec) pointing of the platform. Key features of the design include closed-loop tracking of target bodies using an optical sensor and decoupling of spacecraft dynamics via high-bandwidth, inertially stabilized control. This paper discusses the analyses and design. Computer simulations were used to establish the feasibility of the design approach and to verify that the performance requirements can be met. A breadboard demonstration of the entire system is expected in late 1980.

  11. Homometric Point Sets and Inverse Problems

    CERN Document Server

    Grimm, Uwe

    2008-01-01

    The inverse problem of diffraction theory in essence amounts to the reconstruction of the atomic positions of a solid from its diffraction image. From a mathematical perspective, this is a notoriously difficult problem, even in the idealised situation of perfect diffraction from an infinite structure. Here, the problem is analysed via the autocorrelation measure of the underlying point set, where two point sets are called homometric when they share the same autocorrelation. For the class of mathematical quasicrystals within a given cut and project scheme, the homometry problem becomes equivalent to Matheron's covariogram problem, in the sense of determining the window from its covariogram. Although certain uniqueness results are known for convex windows, interesting examples of distinct homometric model sets already emerge in the plane. The uncertainty level increases in the presence of diffuse scattering. Already in one dimension, a mixed spectrum can be compatible with structures of different entropy. We ex...

  12. PowerPoint 2010 Bible

    CERN Document Server

    Wempen, Faithe

    2010-01-01

    Master PowerPoint and improve your presentation skills-with one book!. It's no longer enough to have slide after slide of text, bullets, and charts. It's not even enough to have good speaking skills if your PowerPoint slides bore your audience. Get the very most out of all that PowerPoint 2010 has to offer while also learning priceless tips and techniques for making good presentations in this new PowerPoint 2010 Bible. Well-known PowerPoint expert and author Faithe Wempen provides formatting tips; shows you how to work with drawings, tables, and SmartArt; introduces new collaboration tools; wa

  13. Imaging study on acupuncture points

    Energy Technology Data Exchange (ETDEWEB)

    Yan, X H; Zhang, X Y [Synchrotron Radiation Research Center, Physics Department, and Surface Physics Laboratory (State Key Laboratory) of Fudan University, Shanghai 200433 (China); Liu, C L [Physics Department of Yancheng Teachers College, Yancheng 224002 (China); Dang, R S [Second Military Medical University, Shanghai 200433 (China); Ando, M [DDS center, Research Institute for Science and Technology, Tokyo University of Science, Yamasaki 2541, Noda, Chiba 278-8510 (Japan); Sugiyama, H [Photon Factory, Institute of Material Structure Science, High Energy Accelerator Research Organization, Oho 1-1, Tsukuba, Ibaraki 305-0801 (Japan); Chen, H S [Institute of Modern Physics, Fudan University, Shanghai 200433 (China); Ding, G H, E-mail: xy-zhang@fudan.edu.c [Shanghai Research Center of Acupuncture and Meridian, Shanghai 201203 (China)

    2009-09-01

    The topographic structures of acupuncture points were investigated by using the synchrotron radiation based Dark Field Image (DFI) method. Four following acupuncture points were studied: Sanyinjiao, Neiguan, Zusanli and Tianshu. We have found that at acupuncture point regions there exists the accumulation of micro-vessels. The images taken in the surrounding tissue out of the acupuncture points do not show such kind of structure. It is the first time to reveal directly the specific structure of acupuncture points by X-ray imaging.

  14. Analysing Old Testament poetry: Basic issues in contemporary exegesis

    Directory of Open Access Journals (Sweden)

    G. T. M. Prinsloo

    1991-08-01

    Full Text Available The wealth of publications on matters relating to Old Testament poetry is witness to the fact that this subject has become a focal point in Old Testament studies. In this paper, an overview of contemporary publications is given. The basic issues, both on the level of poetic theory and practical application, are pointed out. A tendency towards a comprehensive literary approach is definitely present and should be encouraged. Only when a poem is analysed on all levels and by all means, will the richness of its meaning be appreciated.

  15. View Dependent Sequential Point Trees

    Institute of Scientific and Technical Information of China (English)

    Wen-Cheng Wang; Feng Wei; En-Hua Wu

    2006-01-01

    Sequential point trees provide the state-of-the-art technique for rendering point models, by re-arranging hierarchical points sequentially according to geometric errors running on GPU for fast rendering. This paper presents a view dependent method to augment sequential point trees by embedding the hierarchical tree structures in the sequential list of hierarchical points. By the method, two kinds of indices are constructed to facilitate the points rendering in an order mostly from near to far and from coarse to fine. As a result, invisible points can be culled view-dependently in high efficiency for hardware acceleration, and at the same time, the advantage of sequential point trees could be still fully taken. Therefore, the new method can run much faster than the conventional sequential point trees, and the acceleration can be highly promoted particularly when the objects possess complex occlusion relationship and viewed closely because invisible points would be in a high percentage of the points at finer levels.

  16. Automatic incrementalization of Prolog based static analyses

    DEFF Research Database (Denmark)

    Eichberg, Michael; Kahl, Matthias; Saha, Diptikalyan;

    2007-01-01

    Modem development environments integrate various static analyses into the build process. Analyses that analyze the whole project whenever the project changes are impractical in this context. We present an approach to automatic incrementalization of analyses that are specified as tabled logic...... incrementalizing a broad range of static analyses....

  17. From gestural pointing to vocal pointing in the brain

    OpenAIRE

    Loevenbruck, Hélène; Dohen, Marion; Vilain, Coriandre

    2008-01-01

    International audience Deixis, or pointing, is the ability to draw the viewer/listener's attention to an object, a person, a direction or an event. Pointing is involved at different stages of human communication development, in multiple modalities: first with the eyes, then with the finger, then with intonation and finally with syntax. It is ubiquitous and probably universal in human interactions. The role of index-finger pointing in language acquisition suggests that it may be a precursor...

  18. Point to point processing of digital images using parallel computing

    Directory of Open Access Journals (Sweden)

    Eric Olmedo

    2012-05-01

    Full Text Available This paper presents an approach the point to point processing of digital images using parallel computing, particularly for grayscale, brightening, darkening, thresholding and contrast change. The point to point technique applies a transformation to each pixel on image concurrently rather than sequentially. This approach used CUDA as parallel programming tool on a GPU in order to take advantage of all available cores. Preliminary results show that CUDA obtains better results in most of the used filters. Except in the negative filter with lower resolutions images OpenCV obtained better ones, but using images in high resolutions CUDA performance is better.

  19. A point's point of view of stringy geometry

    International Nuclear Information System (INIS)

    The notion of a 'point' is essential to describe the topology of spacetime. Despite this, a point probably does not play a particularly distinguished role in any intrinsic formulation of string theory. We discuss one way to try to determine the notion of a point from a worldsheet point of view. The derived category description of D-branes is the key tool. The case of a flop is analyzed and Π-stability in this context is tied in to some ideas of Bridgeland. Monodromy associated to the flop is also computed via Π-stability and shown to be consistent with previous conjectures. (author)

  20. Zamak samples analyses using EDXRF

    Energy Technology Data Exchange (ETDEWEB)

    Assis, J.T. de; Lima, I.; Monin, V., E-mail: joaquim@iprj.uerj.b, E-mail: inaya@iprj.uerj.b, E-mail: monin@iprj.uerj.b [Universidade do Estado do Rio de Janeiro (UERJ), Nova Friburgo, RJ (Brazil). Inst. Politecnico. Dept. de Engenharia Mecanica e Energia; Anjos, M. dos; Lopes, R.T., E-mail: ricardo@lin.ufrj.b [Coordenacao dos Programas de Pos-graduacao de Engenharia (COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Lab. de Instrumentacao Nuclear; Alves, H., E-mail: marcelin@uerj.b, E-mail: haimon.dlafis@gmail.co [Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ (Brazil). Inst. de Fisica. Dept. de Fisica Aplicada e Termodinamica

    2009-07-01

    Zamak is a family of alloys with a base metal of zinc and alloying elements of aluminium, magnesium and copper. Among all non-ferrous metal alloys, Zamak is one that has more applications, for their physical, mechanical properties and easy ability to electrodeposition. It has good resistance to corrosion, traction, shock and wear. Its low melting point (approximately 400 deg C) allows greater durability of the mold, allowing greater production of melted series parts. Zamak can be used in several kinds of areas, such as, to produce residential and industrial locks, construction and carpentry components, refrigerators hinges and so on. It is observed that in some cases the quality of these products is not very good. The problem should be the quality of Zamak alloy purchased by the industries. One possible technique that can be used to investigate the quality of these alloys is Energy Dispersive X-ray fluorescence. In this paper we present results of eight samples of Zamak alloy by this technique and it was possible to classify Zamak alloy and verify some irregularity on these alloys. (author)

  1. Remarks on Psychological Analyses of Sons and Lovers

    Institute of Scientific and Technical Information of China (English)

    杨艳微

    2007-01-01

    Sons and Lovers is considered to be D.H.Lawrene's first masterpiece. Social critique and psychological exploration are two props of creative works of D.H.Lawrence. There are two points of view in literature world about the novel Sons and Lovers: One is its critical function which criticizes the destroy of capitalistic industrial civilization to human body and mind. The other is psychological analyses. The tragedy of the characters attributes to the Oedipus complex.

  2. A Web-based Tool Combining Different Type Analyses

    DEFF Research Database (Denmark)

    Henriksen, Kim Steen; Gallagher, John Patrick

    2006-01-01

    both, and they can be goal-dependent or goal-independent. We describe a prototype tool that can be accessed from a web browser, allowing various type analyses to be run. The first goal of the tool is to allow the analysis results to be examined conveniently by clicking on points in the original program...... minimal "domain model" of the program with respect to the corresponding pre-interpretation, which can give more precise information than the original descriptive type....

  3. A protein binding AT-rich sequence in the soybean leghemoglobin c3 promoter is a general cis element that requires proximal DNA elements to stimulate transcription

    DEFF Research Database (Denmark)

    Laursen, N B; Larsen, K; Knudsen, J Y;

    1994-01-01

    A nodule nuclear factor, NAT2, interacts with two AT-rich binding sites (NAT2 BS1 and NAT2 BS2) in the soybean leghemoglobin (lb) c3 promoter. In transgenic Lotus corniculatus nodules, an oligonucleotide containing NAT2 BS1 activated an inactive -159 lbc3 promoter when placed immediately upstream...... of the promoter. The activation was independent of the orientation of NAT2 BS1 but was dependent on its position in the promoter. The abilities of different mutated binding sites to activate expression in vivo were correlated to their respective in vitro affinities for binding NAT2. This suggested......(s) is required for the function of NAT2 BS1. Thus, the -102 lbc3 promoter lacking the organ-specific element (-139 to -102) was not reactivated by the presence of the binding site, and the rbcS-8B promoter required sequences between -312 and -257 to be activated by NAT2 BS1. This implies that NAT2 has to work...

  4. Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements.

    Directory of Open Access Journals (Sweden)

    Pegine Walrad

    2009-02-01

    Full Text Available The genome of Trypanosoma brucei is unusual in being regulated almost entirely at the post-transcriptional level. In terms of regulation, the best-studied genes are procyclins, which encode a family of major surface GPI-anchored glycoproteins (EP1, EP2, EP3, GPEET that show differential expression in the parasite's tsetse-fly vector. Although procyclin mRNA cis-regulatory sequences have provided the paradigm for post-transcriptional control in kinetoplastid parasites, trans-acting regulators of procyclin mRNAs are unidentified, despite intensive effort over 15 years. Here we identify the developmental regulator, TbZFP3, a CCCH-class predicted RNA binding protein, as an isoform-specific regulator of Procyclin surface coat expression in trypanosomes. We demonstrate (i that endogenous TbZFP3 shows sequence-specific co-precipitation of EP1 and GPEET, but not EP2 and EP3, procyclin mRNA isoforms, (ii that ectopic overexpression of TbZFP3 does not perturb the mRNA abundance of procyclin transcripts, but rather that (iii their protein expression is regulated in an isoform-specific manner, as evidenced by mass spectrometric analysis of the Procyclin expression signature in the transgenic cell lines. The TbZFP3 mRNA-protein complex (TbZFP3mRNP is identified as a trans-regulator of differential surface protein expression in trypanosomes. Moreover, its sequence-specific interactions with procyclin mRNAs are compatible with long-established predictions for Procyclin regulation. Combined with the known association of TbZFP3 with the translational apparatus, this study provides a long-sought missing link between surface protein cis-regulatory signals and the gene expression machinery in trypanosomes.

  5. Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element.

    Science.gov (United States)

    Felinski, Edward A; Cox, Amy E; Phillips, Brett E; Antonetti, David A

    2008-06-01

    Tight junctions between vascular endothelial cells help to create the blood-brain and blood-retinal barriers. Breakdown of the retinal tight junction complex is problematic in several disease states including diabetic retinopathy. Glucocorticoids can restore and/or preserve the endothelial barrier to paracellular permeability, although the mechanism remains unclear. We show that glucocorticoid treatment of primary retinal endothelial cells increases content of the tight junction proteins occludin and claudin-5, co-incident with an increase in barrier properties of endothelial monolayers. The glucocorticoid receptor antagonist RU486 reverses both the glucocorticoid-stimulated increase in occludin content and the increase in barrier properties. Transcriptional activity from the human occludin and claudin-5 promoters increases in retinal endothelial cells upon glucocorticoid treatment, and is dependent on the glucocorticoid receptor (GR) as demonstrated by siRNA. Deletion analysis of the occludin promoter reveals a 205bp sequence responsible for the glucocorticoid response. However, this region does not possess a canonical glucocorticoid response element and does not bind to the GR in a chromatin immunoprecipitation (ChIP) assay. Mutational analysis of this region revealed a novel 40bp occludin enhancer element (OEE), containing two highly conserved regions of 10 and 13 base pairs, that is both necessary and sufficient for glucocorticoid-induced gene expression in retinal endothelial cells. These data suggest a novel mechanism for glucocorticoid induction of vascular endothelial barrier properties through increased occludin and claudin-5 gene expression. PMID:18501346

  6. The role of promoter cis-element, mRNA capping, and ROS in the repression and salt-inducible expression of AtSOT12 in Arabidopsis

    Directory of Open Access Journals (Sweden)

    Jinhua eChen

    2015-11-01

    Full Text Available Inducible gene expression is a gene regulatory mechanism central to plant response to environmental cues. The inducible genes are often repressed under normal growth conditions while their expression levels are significantly elevated by conditions such as abiotic stresses. Induction of gene expression requires both cis-acting DNA elements and trans-acting proteins that are modulated through signal transduction pathways. Here we report several molecular events that affect salt induced expression of the Arabidopsis AtSOT12 gene. Promoter deletion analysis revealed that DNA elements residing in the 5’ UTR are required for the salt induced expression of AtSOT12. Cytosine methylation in the promoter was low and salt stress slightly increased the DNA methylation level, suggesting that DNA methylation may not contribute to AtSOT12 gene repression. Co-transcriptional processing of AtSOT12 mRNA including capping and polyadenylation site selection was also affected by salt stress. The percentage of capped mRNA increased by salt treatment, and the polyadenylation sites were significantly different before and after exposure to salt stress. The expression level of AtSOT12 under normal growth conditions was markedly higher in the oxi1 mutant defective of ROS signaling than in the wild type. Moreover, AtSOT12 transcript level was elevated by treatments with DPI and DMTU, two chemicals preventing reactive oxygen species (ROS accumulation. These results suggest that repression of AtSOT12 expression may require physiological level of ROS and ROS signaling.

  7. Identification of SmtB/ArsR cis elements and proteins in archaea using the Prokaryotic InterGenic Exploration Database (PIGED

    Directory of Open Access Journals (Sweden)

    Michael Bose

    2006-01-01

    Full Text Available Microbial genome sequencing projects have revealed an apparently wide distribution of SmtB/ArsR metal-responsive transcriptional regulators among prokaryotes. Using a position-dependent weight matrix approach, prokaryotic genome sequences were screened for SmtB/ArsR DNA binding sites using data derived from intergenic sequences upstream of orthologous genes encoding these regulators. Sixty SmtB/ArsR operators linked to metal detoxification genes, including nine among various archaeal species, are predicted among 230 annotated and draft prokaryotic genome sequences. Independent multiple sequence alignments of putative operator sites and corresponding winged helix-turn-helix motifs define sequence signatures for the DNA binding activity of this SmtB/ArsR subfamily. Prediction of an archaeal SmtB/ArsR based upon these signature sequences is confirmed using purified Methanosarcina acetivorans C2A protein and electrophoretic mobility shift assays. Tools used in this study have been incorporated into a web application, the Prokaryotic InterGenic Exploration Database (PIGED; http://bioinformatics.uwp.edu/~PIGED/home.htm, facilitating comparable studies. Use of this tool and establishment of orthology based on DNA binding signatures holds promise for deciphering potential cellular roles of various archaeal winged helix-turn-helix transcriptional regulators.

  8. A TGACGT motif in the 5'-upstream region of alpha-amylase gene from Vigna mungo is a cis-element for expression in cotyledons of germinated seeds.

    Science.gov (United States)

    Yamauchi, D

    2001-06-01

    Alpha-amylase is expressed at high levels in cotyledons of germinated seeds of Vigna mungo. The mRNA for alpha-amylase appeared in cotyledons of the seeds at 1 d after imbibition started (DAI). Two TGACGT motifs at -445 and at -125 in the promoter region of the gene interacted with nuclear proteins from cotyledons of dry seeds and the activities were detected until 3 DAI. A transient assay with particle bombardment showed that the downstream region from -135 in the promoter was required for high level expression in the cotyledons and the activity was reduced by mutation of the TGACGT motif at -125. The activities to bind the TGACGT motifs were detected in the axes of the seeds at 1 DAI but disappeared at 4 DAI, although the mRNA for alpha-amylase in the axes appeared at 4 DAI and increased in level by 6 DAI. A transient assay experiment showed that a positive regulatory element for the expression in the axes was located in the region from -630 to -453. These results indicated that the TGACGT motif at -125 was required for high level expression of the gene in the cotyledons of the germinated seeds.

  9. Transcription factors binding to the cis-elements of GADD45 gene in ML-1 cells after low-dose irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Daino, Kazuhiro [Chiba Univ., Faculty of Science, Chiba (Japan); Ichimura, Sachiko; Nenoi, Mitsuru [National Inst. of Radiological Sciences, Chiba (Japan)

    2003-07-01

    Several stress-responsive genes, including p53-target genes, are induced by low-dose of ionizing radiation ranging from 0.02 to 0.5 Gy. We show here that 0.5 Gy of X-rays increase the transcription rate of the GADD45 gene, with maximum induction at 0.5 to 1 h after irradiation, much earlier than the maximum accumulation of stabilized p53 protein. It could be suggested that some transcription factors cooperate with p53 in regulating the GADD45 gene at an early time after low-dose irradiation. This idea is supported by the studies that showed GKLF and Spl are required for p53-dependent transcriptional activation of the p21{sup WAFI/Cipl} and BAX genes, respectively. To examine the possible involvement of cooperating transcription factors in regulation of the GADD45 gene after low-dose radiation, we attempted a comprehensive EMSA, in which 136 species of double-stranded DNA probes were used to identify X-ray-inducible factor-bindings to the upstream and the third intron regions of the gene after exposure to 0.5 Gy of X-rays in human myeloblastic leukemia ML-1 cells. Several X-ray-inducible DNA-protein complexes were observed. The factors related to forkhead transcription factors, POU domain transcription factors and kruppel-like factors were putatively identified by the competition assay. It is possible that these factors cooperate with p53 to mediate the transcriptional regulation of the GADD45 genes after low-dose irradiation. (author)

  10. CstF-64 and 3′-UTR cis-element determine Star-PAP specificity for target mRNA selection by excluding PAPα

    OpenAIRE

    Kandala, Divya T.; Mohan, Nimmy; A, Vivekanand; AP, Sudheesh; G, Reshmi; Laishram, Rakesh S.

    2015-01-01

    Almost all eukaryotic mRNAs have a poly (A) tail at the 3′-end. Canonical PAPs (PAPα/γ) polyadenylate nuclear pre-mRNAs. The recent identification of the non-canonical Star-PAP revealed specificity of nuclear PAPs for pre-mRNAs, yet the mechanism how Star-PAP selects mRNA targets is still elusive. Moreover, how Star-PAP target mRNAs having canonical AAUAAA signal are not regulated by PAPα is unclear. We investigate specificity mechanisms of Star-PAP that selects pre-mRNA targets for polyadeny...

  11. Regulation of tissue-specific alternative splicing: exon-specific cis-elements govern the splicing of leukocyte common antigen pre-mRNA.

    OpenAIRE

    Streuli, M; Saito, H

    1989-01-01

    Tissue-specific alternative splicing is an important mechanism for controlling gene expression. Exons 4, 5 and 6 of the human leukocyte common antigen (LCA) gene are included in B cell mRNA but excluded from thymocyte mRNA by differential splicing. In order to study this tissue-specific alternative splicing, we constructed mini-genes that contain only a few of the LCA exons and the SV40 promoter. Mouse B cells and thymocytes were transfected with these mini-gene constructs and the structures ...

  12. Integrated Field Analyses of Thermal Springs

    Science.gov (United States)

    Shervais, K.; Young, B.; Ponce-Zepeda, M. M.; Rosove, S.

    2011-12-01

    A group of undergraduate researchers through the SURE internship offered by the Southern California Earthquake Center (SCEC) have examined thermal springs in southern Idaho, northern Utah as well as mud volcanoes in the Salton Sea, California. We used an integrated approach to estimate the setting and maximum temperature, including water chemistry, Ipad-based image and data-base management, microbiology, and gas analyses with a modified Giggenbach sampler.All springs were characterized using GISRoam (tmCogent3D). We are performing geothermometry calculations as well as comparisons with temperature gradient data on the results while also analyzing biological samples. Analyses include water temperature, pH, electrical conductivity, and TDS measured in the field. Each sample is sealed and chilled and delivered to a water lab within 12 hours.Temperatures are continuously monitored with the use of Solinst Levelogger Juniors. Through partnership with a local community college geology club, we receive results on a monthly basis and are able to process initial data earlier in order to evaluate data over a longer time span. The springs and mudpots contained microbial organisms which were analyzed using methods of single colony isolation, polymerase chain reaction, and DNA sequencing showing the impact of the organisms on the springs or vice versa. Soon we we will collect gas samples at sites that show signs of gas. This will be taken using a hybrid of the Giggenbach method and our own methods. Drawing gas samples has proven a challenge, however we devised a method to draw out gas samples utilizing the Giggenbach flask, transferring samples to glass blood sample tubes, replacing NaOH in the Giggenbach flask, and evacuating it in the field for multiple samples using a vacuum pump. We also use a floating platform devised to carry and lower a levelogger, to using an in-line fuel filter from a tractor in order to keep mud from contaminating the equipment.The use of raster

  13. NOx analyser interefence from alkenes

    Science.gov (United States)

    Bloss, W. J.; Alam, M. S.; Lee, J. D.; Vazquez, M.; Munoz, A.; Rodenas, M.

    2012-04-01

    Nitrogen oxides (NO and NO2, collectively NOx) are critical intermediates in atmospheric chemistry. NOx abundance controls the levels of the primary atmospheric oxidants OH, NO3 and O3, and regulates the ozone production which results from the degradation of volatile organic compounds. NOx are also atmospheric pollutants in their own right, and NO2 is commonly included in air quality objectives and regulations. In addition to their role in controlling ozone formation, NOx levels affect the production of other pollutants such as the lachrymator PAN, and the nitrate component of secondary aerosol particles. Consequently, accurate measurement of nitrogen oxides in the atmosphere is of major importance for understanding our atmosphere. The most widely employed approach for the measurement of NOx is chemiluminescent detection of NO2* from the NO + O3 reaction, combined with NO2 reduction by either a heated catalyst or photoconvertor. The reaction between alkenes and ozone is also chemiluminescent; therefore alkenes may contribute to the measured NOx signal, depending upon the instrumental background subtraction cycle employed. This interference has been noted previously, and indeed the effect has been used to measure both alkenes and ozone in the atmosphere. Here we report the results of a systematic investigation of the response of a selection of NOx analysers, ranging from systems used for routine air quality monitoring to atmospheric research instrumentation, to a series of alkenes ranging from ethene to the biogenic monoterpenes, as a function of conditions (co-reactants, humidity). Experiments were performed in the European Photoreactor (EUPHORE) to ensure common calibration, a common sample for the monitors, and to unequivocally confirm the alkene (via FTIR) and NO2 (via DOAS) levels present. The instrument responses ranged from negligible levels up to 10 % depending upon the alkene present and conditions used. Such interferences may be of substantial importance

  14. Improved Dynamic Planar Point Location

    DEFF Research Database (Denmark)

    Brodal, Gerth Stølting; Arge, Lars; Georgiadis, Loukas

    2006-01-01

    We develop the first linear-space data structures for dynamic planar point location in general subdivisions that achieve logarithmic query time and poly-logarithmic update time.......We develop the first linear-space data structures for dynamic planar point location in general subdivisions that achieve logarithmic query time and poly-logarithmic update time....

  15. Target-point formation control

    NARCIS (Netherlands)

    Mou, Shaoshuai; Cao, Ming; Morse, A. Stephen

    2015-01-01

    In this paper a new distributed feedback strategy is proposed for controlling a rigid, acyclic formation of kinematic point-modeled mobile autonomous agents in the plane. The strategy makes use of a new concept called a "target point" and is applicable to any two-dimensional, acyclic formation whose

  16. ATLAS Civil Engineering Point 1

    CERN Multimedia

    Jean-Claude Vialis

    1998-01-01

    Different phases of the PX 15 realisation to Point 1: zone of the ATLAS experiment 19-11-1998 Realisation of the Walkway for PX 15 and the putting up scaffolds 15-01-1999 Film from the surface of Point 1 and descent in the well of PX 15

  17. Brocard Point and Euler Function

    Science.gov (United States)

    Sastry, K. R. S.

    2007-01-01

    This paper takes a known point from Brocard geometry, a known result from the geometry of the equilateral triangle, and bring in Euler's [empty set] function. It then demonstrates how to obtain new Brocard Geometric number theory results from them. Furthermore, this paper aims to determine a [triangle]ABC whose Crelle-Brocard Point [omega]…

  18. The Philosophy of Turning Points

    DEFF Research Database (Denmark)

    Turcan, Romeo V.

    2013-01-01

    business and management field, the turning point is seen as a valuable unit of analysis within the research field. It is expected that this paper will encourage a dynamic scholarly conversation about the concept of turning point and how it can aid international business researchers in the development...

  19. Mathematical points as didactical ideas

    DEFF Research Database (Denmark)

    Mogensen, Arne

    2012-01-01

    Mathematics teaching in Denmark was recently recommended better organized in sequences with clear mathematical pedagogical goals and a focus on mathematical points. In this paper I define a mathematical point and inform on coding of transcripts in a video based Danish research study on grade 8 te...

  20. Heilbronn problem for five points

    International Nuclear Information System (INIS)

    Put 5 points in a unit square, then there must be at least one triangle, formed by three of these points, with an area not greater than √3/9. And the upper bound √3/9 is the best. Unexpectedly, this disproves an old conjecture posed twenty years ago. (author). 15 refs, 19 figs

  1. ATLAS Civil Engineering Point 1

    CERN Multimedia

    Jean-Claude Vialis

    1999-01-01

    Different phases of realisation to Point 1 : zone of the ATLAS experiment The ATLAS experimental area is located in Point 1, just across the main CERN entrance, in the commune of Meyrin. There people are ever so busy to finish the different infrastructures for ATLAS. Real underground video. The film has original working sound.

  2. Pawnee Nation Energy Option Analyses

    Energy Technology Data Exchange (ETDEWEB)

    Matlock, M.; Kersey, K.; Riding In, C.

    2009-07-21

    Pawnee Nation of Oklahoma Energy Option Analyses In 2003, the Pawnee Nation leadership identified the need for the tribe to comprehensively address its energy issues. During a strategic energy planning workshop a general framework was laid out and the Pawnee Nation Energy Task Force was created to work toward further development of the tribe’s energy vision. The overarching goals of the “first steps” project were to identify the most appropriate focus for its strategic energy initiatives going forward, and to provide information necessary to take the next steps in pursuit of the “best fit” energy options. Description of Activities Performed The research team reviewed existing data pertaining to the availability of biomass (focusing on woody biomass, agricultural biomass/bio-energy crops, and methane capture), solar, wind and hydropower resources on the Pawnee-owned lands. Using these data, combined with assumptions about costs and revenue streams, the research team performed preliminary feasibility assessments for each resource category. The research team also reviewed available funding resources and made recommendations to Pawnee Nation highlighting those resources with the greatest potential for financially-viable development, both in the near-term and over a longer time horizon. Findings and Recommendations Due to a lack of financial incentives for renewable energy, particularly at the state level, combined mediocre renewable energy resources, renewable energy development opportunities are limited for Pawnee Nation. However, near-term potential exists for development of solar hot water at the gym, and an exterior wood-fired boiler system at the tribe’s main administrative building. Pawnee Nation should also explore options for developing LFGTE resources in collaboration with the City of Pawnee. Significant potential may also exist for development of bio-energy resources within the next decade. Pawnee Nation representatives should closely monitor

  3. Limit Cycles near Stationary Points in the Lorenz System

    Institute of Scientific and Technical Information of China (English)

    YANG Shi-Pu; ZHU Ke-Qin; ZHOU Xiao-Zhou

    2005-01-01

    @@ The limit cycles in the Lorenz system near the stationary points are analysed numerically. A plane in phase space of the linear Lorenz system is used to locate suitable initial points of trajectories near the limit cycles. The numerical results show a stable and an unstable limit cycle near the stationary point. The stable limit cycle is smaller than the unstable one and has not been previously reported in the literature. In addition, all the limit cycles in the Lorenz system are theoretically proven not to be planar.

  4. Equilibrium points and bifurcation control of a chaotic system

    Institute of Scientific and Technical Information of China (English)

    Liang Cui-Xiang; Tang Jia-Shi

    2008-01-01

    Based on the Routh-Hurwitz criterion,this paper investigates the stability of a new chaotic system.State feedback controllers are designed to control the chaotic system to the unsteady equilibrium points and limit cycle.Theoretical analyses give the range of value of control parameters to stabilize the unsteady equilibrium points of the chaotic system and its critical parameter for generating Hopf bifurcation.Certain nP periodic orbits can be stabilized by parameter adjustment.Numerical simulations indicate that the method can effectively guide the system trajectories to unsteady equilibrium points and periodic orbits.

  5. Building Points - MO 2014 Barton Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  6. Building Points - MO 2014 Camden Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  7. Building Points - MO 2014 Dade Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  8. Building Points - MO 2014 Clark Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  9. Building Points - MO 2014 Audrain Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  10. Building Points - MO 2014 Christian Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  11. Building Points - MO 2014 Bates Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  12. Building Points - MO 2014 Benton Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  13. Building Points - MO 2014 Butler Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  14. Geodetic Control Points - Multi-State Control Point Database

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — The Multi-State Control Point Database (MCPD) is a database of geodetic and mapping control covering Idaho and Montana. The control were submitted by registered...

  15. Building Points - MO 2014 Crawford Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  16. Building Points - MO 2014 Clinton Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  17. Building Points - MO 2014 Atchison Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  18. Building Points - MO 2014 Carroll Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  19. Building Points - MO 2014 Buchanan Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  20. Building Points - MO 2014 Caldwell Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  1. Building Points - MO 2014 Cedar Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  2. Building Points - MO 2014 Clay Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  3. Building Points - MO 2014 Barry Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  4. Building Points - MO 2014 Chariton Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  5. Building Points - MO 2014 Dallas Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  6. Building Points - MO 2014 Daviess Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  7. Building Points - MO 2014 Adair Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  8. Building Points - MO 2014 Cass Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  9. Building Points - MO 2014 Andrew Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  10. Building Points - MO 2012 Iron Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed categorized points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  11. Building Points - MO 2012 Perry Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed categorized points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  12. Building Points - MO 2012 Cape Girardeau Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed categorized points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  13. Building Points - MO 2012 Madison Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed categorized points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  14. Building Points - MO 2012 Bollinger Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed categorized points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  15. Building Points - MO 2012 St. Genevieve Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed categorized points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  16. Building Points - MO 2012 St. Francois Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed categorized points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  17. Building Points - MO 2014 Carter Structure Points (SHP)

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — Staff at the Geographic Resources Center placed attributed points on all roofed structures visible at a scale of 1:2000 using MSDIS-DOQQ 2008 2-foot aerial imagery...

  18. Flood frequency analyses with annual and partial flood series

    Science.gov (United States)

    Bezak, N.; Brilly, M.; Sraj, M.

    2012-04-01

    The objective of the study was (1) to analyse the influence of time scale of the data on the results, (2) to analyse the relations between discharge, volume and time of flood waves of the Sava river at Litija (Slovenia), (3) to perform flood frequency analyses of peak discharges with annual and partial data series and compare the results and (4) to explore the influence of threshold value by POT method. Calculations and analyses were made for the period 1953-2010. Daily scale data sets (considering also local maximum) were used. The flood frequency analyses were based on anual and partial data series. The differences between daily and hourly time scale data sets were explored. Daily and hourly time scale hydrographs were compared and differences were analysed. Differences were adequately small. Daily time series with included maximums were logical choice because of the length of the daily time series and because hourly time series were not continuous due to gauging equipment failures. Important objective of the study was to analyse the relationship between discharge, volume and duration of flood waves. Baseflow was separated from continuous daily discharge measurements on simple and complex hydrographs. Simple graphical method with three points was used. Many different coefficients like base flow index were calculated and different combinations of correlation coefficient of wave components were examined. Annual maximum series were used to study the relationship between wave components. Flood frequency analyses were made with annual maximum series and partial duration series. Log-normal distribution, Pearson distribution type 3, log-Pearson distribution type 3, Gumbel distribution, exponential distribution, GEV distribution and GL distribution were used for annual maximum series. Simple equation of linear transformation was used to determine the design discharge and procedure which is proposed in Flood Estimation Handbook was used with GEV and GL distribution

  19. Pivots for Pointing: Visually-Monitored Pointing Has Higher Arm Elevations than Pointing Blindfolded

    Science.gov (United States)

    Wnuczko, Marta; Kennedy, John M.

    2011-01-01

    Observers pointing to a target viewed directly may elevate their fingertip close to the line of sight. However, pointing blindfolded, after viewing the target, they may pivot lower, from the shoulder, aligning the arm with the target as if reaching to the target. Indeed, in Experiment 1 participants elevated their arms more in visually monitored…

  20. n-point Single-Minus Gravity Amplitudes

    CERN Document Server

    Alston, Sam D; Perkins, Warren B

    2015-01-01

    We construct an expression for the n-point one-loop graviton scattering amplitude with a single negative helicity external leg using an augmented recursion technique. We analyse the soft-limits of these amplitudes and demonstrate that they have soft behaviour beyond the conjectured universal behaviour.

  1. Modelling of Landslides with the Material-point Method

    DEFF Research Database (Denmark)

    Andersen, Søren; Andersen, Lars

    2009-01-01

    A numerical model for studying the dynamic evolution of landslides is presented. The numerical model is based on the Generalized Interpolation Material Point Method. A simplified slope with a house placed on top is analysed. An elasto-plastic material model based on the Mohr-Coulomb yield criterion...

  2. A Point-Wise Quantification of Asymmetry Using Deformation Fields

    DEFF Research Database (Denmark)

    Ólafsdóttir, Hildur; Lanche, Stephanie; Darvann, Tron Andre;

    2007-01-01

    This paper introduces a novel approach to quantify asymmetry in each point of a surface. The measure is based on analysing displacement vectors resulting from nonrigid image registration. A symmetric atlas, generated from control subjects is registered to a given subject image. A comparison of th...

  3. Modeling of Landslides with the Material Point Method

    DEFF Research Database (Denmark)

    Andersen, Søren Mikkel; Andersen, Lars

    2008-01-01

    A numerical model for studying the dynamic evolution of landslides is presented. The numerical model is based on the Generalized Interpolation Material Point Method. A simplified slope with a house placed on top is analysed. An elasto-plastic material model based on the Mohr-Coulomb yield criterion...

  4. Positional nystagmus showing neutral points.

    Science.gov (United States)

    Hiruma, Kiyoshi; Numata, Tsutomu

    2004-01-01

    We encountered patients who had their static direction-changing positional nystagmus canceled at about 20-30 degrees yaw head rotation from the supine position. This nystagmus was also canceled when the head was rotated 180 degrees from this position. We call these head positions neutral points. At the neutral points, the cupula of the horizontal semicircular canal of the affected ear is positioned vertical to the gravitational plane and no deflection of the cupula occurs. The positional nystagmus observed (except the neutral points) was thought to occur due to a "heavy cupula" or "light cupula", which may be determined by the specific gravity of its endolymph.

  5. PowerPoint 2013 bible

    CERN Document Server

    Wempen, Faithe

    2013-01-01

    Master PowerPoint and improve your presentation skills with one book! In today's business climate, you need to know PowerPoint inside and out, and that's not all. You also need to be able to make a presentation that makes an impact. From using sophisticated transitions and animation in your PowerPoint presentations to interfacing in person with your audience, this information-packed book helps you succeed. Start creating professional-quality slides that captivate audiences and discover essential tips and techniques for making first-rate presentations, whether you're at a podium or

  6. Cleaning Massive Sonar Point Clouds

    DEFF Research Database (Denmark)

    Arge, Lars Allan; Larsen, Kasper Green; Mølhave, Thomas;

    2010-01-01

    We consider the problem of automatically cleaning massive sonar data point clouds, that is, the problem of automatically removing noisy points that for example appear as a result of scans of (shoals of) fish, multiple reflections, scanner self-reflections, refraction in gas bubbles, and so on. We...... describe a new algorithm that avoids the problems of previous local-neighbourhood based algorithms. Our algorithm is theoretically I/O-efficient, that is, it is capable of efficiently processing massive sonar point clouds that do not fit in internal memory but must reside on disk. The algorithm is also...

  7. Geometric Computations On Indecisive Points

    DEFF Research Database (Denmark)

    Jørgensen, Allan Grønlund; Phillips, Jeff; Loffler, Maarten

    2011-01-01

    We study computing with indecisive point sets. Such points have spatial uncertainty where the true location is one of a finite number of possible locations. This data arises from probing distributions a few times or when the location is one of a few locations from a known database. In particular,......-hard. We generalize our polynomial-time algorithm to all LP-type problems. We also utilize our indecisive framework to deterministically and approximately compute on a more general class of uncertain data where the location of each point is given by a probability distribution....

  8. ATLAS: civil engineering Point 1

    CERN Multimedia

    2000-01-01

    The construction work at point one was a massive site including overground and underground work. Point 1 under construction is worth to see.Tools and machinery used during the construction and the multible scenes with people working in different parts of point1. Scenes from the 3D CAD office and some talking in english. Printing out drawings and later views of the empty tunnel were the LHC accelerator is installed 80m under the surface.The film gives the view to the close history in other words to the time before the installations.

  9. ATLAS Civil Engineering Point 1

    CERN Multimedia

    Jean-Claude Vialis

    1998-01-01

    Different phases of realisation to Point 1 : zone of the ATLAS experiment After watching this film you can get the view of the civil engineering work at POINT1 where the ATLAS will be built. 03-11-1998 The video starts with the view of the POINT1 taken from the roof of the building 33. 04-11-1998 View of the installation of the entrance of the SDX1 18/19-11-1998 Installation of the rafters to the building PX15

  10. Calcareous Fens - Source Feature Points

    Data.gov (United States)

    Minnesota Department of Natural Resources — Pursuant to the provisions of Minnesota Statutes, section 103G.223, this database contains points that represent calcareous fens as defined in Minnesota Rules, part...

  11. Pointing Refinement of SIRTF Images

    CERN Document Server

    Masci, F; Moshir, M; Shupe, D; Fowler, J W; Fowler, John W.

    2002-01-01

    The soon-to-be-launched Space Infrared Telescope Facility (SIRTF) shall produce image data with an a-posteriori pointing knowledge of 1.4 arcsec (1 sigma radial) with a goal of 1.2 arcsec in the International Celestial Reference System (ICRS). To perform robust image coaddition, mosaic generation, extraction and position determination of faint sources, the pointing will need to be refined to better than a few-tenths of an arcsecond. We use a linear-sparse matrix solver to find a "global-minimization" of all relative image offsets in a mosaic from which refined pointings and orientations can be computed. This paper summarizes the pointing-refinement algorithm and presents the results of testing on simulated data.

  12. Parametric statistical change point analysis

    CERN Document Server

    Chen, Jie

    2000-01-01

    This work is an in-depth study of the change point problem from a general point of view and a further examination of change point analysis of the most commonly used statistical models Change point problems are encountered in such disciplines as economics, finance, medicine, psychology, signal processing, and geology, to mention only several The exposition is clear and systematic, with a great deal of introductory material included Different models are presented in each chapter, including gamma and exponential models, rarely examined thus far in the literature Other models covered in detail are the multivariate normal, univariate normal, regression, and discrete models Extensive examples throughout the text emphasize key concepts and different methodologies are used, namely the likelihood ratio criterion, and the Bayesian and information criterion approaches A comprehensive bibliography and two indices complete the study

  13. Analysis of irregularly distributed points

    DEFF Research Database (Denmark)

    Hartelius, Karsten

    1996-01-01

    The present thesis is on the analysis of irregularly distributed points. The main part of the thesis is concerned with enterpolating and restoration of irregularly distribyted points. The least squares methods of kriging and Kalman filtering and the Bayesian restoration method of iterated...... is described as a robust estimator which may be appled straightfor- wardly to a wide range of point patterns and processes when the correlation structure is known. We give a qualitative and quantitative comparison of kriging, Kalman filter and iterated conditional modes. The Kalman filter have in a case study......, but the usage of simple kriging may lead to ill-conditioned matrices when applied to highly irregularly distributed points. Adaptive Kalman filter schemes are investigated. A new parallel Kalman filter algorithm based on windowing technique gives good results in a case study on the Igallico satellite scene...

  14. Hawaii ESI: NESTS (Nest Points)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains sensitive biological resource data for seabird nesting colonies in coastal Hawaii. Vector points in this data set represent locations of...

  15. Virginia ESI: REPTPT (Reptile Points)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains sensitive biological resource data for sea turtles in Virginia. Vector points in this data set represent nesting sites. Species-specific...

  16. Control Point Generated PLS - lines

    Data.gov (United States)

    Minnesota Department of Natural Resources — The Control Point Generated PLS layer contains line and polygon features to the 1/4 of 1/4 PLS section (approximately 40 acres) and government lot level. The layer...

  17. Louisiana ESI: NESTS (Nest Points)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains sensitive biological resource data for seabird and wading bird nesting colonies in coastal Louisiana. Vector points in this data set...

  18. Point Lobos Rocket Launch [video

    OpenAIRE

    Yakimenko, Oleg; Naval Postgraduate School (U.S.)

    2010-01-01

    The Naval Postgraduate School (NPS) and the AIAA Point Lobos section (PLS) entered three rockets into the 2010 AIAA Young Professionals Rocket Competition (YPRC). The event took place in the Mojave Desert on Koehn Dry lakebed July 17th 2010.

  19. Nucleation of point defect agglomerates

    International Nuclear Information System (INIS)

    A theory of the agglomeration of point defects into dislocation loops and voids is formulated. A critical comparison between theory and experiment is made for nickel and copper irradiated in a high voltage electron microscope

  20. Control Point Generated PLS - polygons

    Data.gov (United States)

    Minnesota Department of Natural Resources — The Control Point Generated PLS layer contains line and polygon features to the 1/4 of 1/4 PLS section (approximately 40 acres) and government lot level. The layer...

  1. Allegheny County Cell Tower Points

    Data.gov (United States)

    Allegheny County / City of Pittsburgh / Western PA Regional Data Center — This dataset portrays cell tower locations as points in Allegheny County. The dataset is based on outbuilding codes in the Property Assessment Parcel Database used...

  2. ATLAS Civil Engineering Point 1

    CERN Multimedia

    2001-01-01

    Different phases of realisation to Point 1: zone of the ATLAS experiment 14-02-2001Realising anchorage, isolations and scaffoldings at UX 15 18-04-2001Concreting the arch and posing the metal reinforcements at UX 15

  3. Articulation Points in Complex Networks

    CERN Document Server

    Tian, Liang; Shi, Da-Ning; Liu, Yang-Yu

    2016-01-01

    An articulation point in a network is a node whose removal disconnects the network. Those nodes play key roles in ensuring connectivity of many real-world networks, from infrastructure networks to protein interaction networks and terrorist communication networks. Despite their fundamental importance, a general framework of studying articulation points in complex networks is lacking. Here we develop analytical tools to study key issues pertinent to articulation points, e.g. the expected number of them and the network vulnerability against their removal, in an arbitrary complex network. We find that a greedy articulation point removal process provides us a novel perspective on the organizational principles of complex networks. Moreover, this process is associated with two fundamentally different types of percolation transitions with a rich phase diagram. Our results shed light on the design of more resilient infrastructure networks and the effective destruction of terrorist communication networks.

  4. SharePoint User's Guide

    CERN Document Server

    Corporation, Infusion Development

    2009-01-01

    This straightforward guide shows SharePoint users how to create and use web sites for sharing and collaboration. Learn to use the document and picture libraries for adding and editing content, add discussion boards and surveys, receive alerts when documents and information have been added or changed, and enhance security. Designed to help you find answers quickly, the book shows how to make the most of SharePoint for productivity and collaboration.

  5. Epsilon Nielsen fixed point theory

    OpenAIRE

    Brown, Robert F.

    2006-01-01

    Let be a map of a compact, connected Riemannian manifold, with or without boundary. For sufficiently small, we introduce an -Nielsen number that is a lower bound for the number of fixed points of all self-maps of that are -homotopic to . We prove that there is always a map that is -homotopic to such that has exactly fixed points. We describe procedures for calculating for maps of -manifolds.

  6. Nevanlinna Theory and Rational Points

    OpenAIRE

    Noguchi, Junjiro

    1996-01-01

    S. Lang conjectured in 1974 that a hyperbolic algebraic variety defined over a number field has only finitely many rational points, and its analogue over function fields. We discuss the Nevanlinna-Cartan theory over function fields of arbitrary dimension and apply it for Diophantine property of hyperbolic projective hypersurfaces (homogeneous Diophantine equations) constructed by Masuda-Noguchi. We also deal with the finiteness property of $S$-units points of those Diophantine equations over ...

  7. Uranium Critical Point Location Problem

    CERN Document Server

    Iosilevskiy, Igor

    2013-01-01

    Significant uncertainty of our present knowledge for uranium critical point parameters is under consideration. Present paper is devoted to comparative analysis of possible resolutions for the problem of uranium critical point location, as well as to discussion of plausible scheme of decisive experiment, which could resolve existing uncertainty. New calculations of gas-liquid coexistence in uranium by modern thermodynamic code are included in the analysis.

  8. Developing SharePoint applications

    OpenAIRE

    Rupnik, Gašper

    2011-01-01

    The thesis includes a research on SharePoint 2010 programming capabilities and a display of products created by this knowledge. The introduction part includes background information on how the topic was chosen and how the thesis was developed. The second chapter presents the SharePoint platform, which includes a description of its structure, function and usability. The third chapter focuses solely on the programming of the platform. First, some of the most useful software tools for i...

  9. Fingerprint Reference-Point Detection

    OpenAIRE

    Liu Manhua; Jiang Xudong; Kot Alex Chichung

    2005-01-01

    A robust fingerprint recognition algorithm should tolerate the rotation and translation of the fingerprint image. One popular solution is to consistently detect a unique reference point and compute a unique reference orientation for translational and rotational alignment. This paper develops an effective algorithm to locate a reference point and compute the corresponding reference orientation consistently and accurately for all types of fingerprints. To compute the reliable orientation field...

  10. ATLAS Civil Engineering Point 1

    CERN Multimedia

    Jean-Claude Vialis

    2000-01-01

    Different phases of realisation to Point 1 : zone of the ATLAS experiment The ATLAS experimental area is located in Point 1, just across the main CERN entrance, in the commune of Meyrin. There people are ever so busy to finish the different infrastructures for ATLAS. Real underground video. When passing throw the walls the succeeding can be heard and seen. The film has original working sound.

  11. ATLAS Civil Engineering Point 1

    CERN Multimedia

    Jean-Claude Vialis

    2000-01-01

    Different phases of realisation to Point 1 : zone of the ATLAS experiment The film is about the excavation work in the cavern and tunnels of ATLAS experiment in the point 1. You can see people working for iron mounting at the side of the pit where the parts of the detector will be lowered in the future. Partly the film concentrates the USA 15 and the work done there.

  12. Point-Force Energy Coupling

    Science.gov (United States)

    Burton, Tristan; Squires, Kyle

    2005-11-01

    Fully resolved simulations of particle-laden turbulent flows are computationally expensive even with a single particle. Therefore, simulations of flows with realistic numbers of particles typically treat the disperse phase as point-particles and models are used to account for the interaction between the phases. The particle trajectories are determined using a Lagrangian particle equation of motion that accounts for the fluid forces. The effect of the particulate phase on the fluid is included using point-force momentum coupling, where the opposite of the force applied to each particle by the fluid is distributed back to fluid grid points in a local region. In this work, we perform direct numerical simulation (DNS) of a particle moving at a prescribed constant or time-dependent velocity through a stationary fluid, and use the resulting force history in a corresponding point-force simulation to study point-force energy coupling. The energy input from the moving particle and the fluid dissipation in the DNS are compared to corresponding quantities in the unresolved calculation. A range of particle Reynolds numbers and ratios of the particle diameter to the unresolved grid spacing are considered to determine the conditions under which point-force momentum coupling provides accurate energy coupling.

  13. WHO Standard Acupuncture Point Locations

    Directory of Open Access Journals (Sweden)

    Sabina Lim

    2010-01-01

    Full Text Available ‘WHO Standard Acupuncture Point Locations in the Western Pacific Region (WHO Standard was released in 2008. Initially, there were 92/361 controversial acupuncture points (acupoints. Through seven informal consultations and four task force team meetings, 86 points were agreed upon among the 92 controversial acupoints, leaving 6 remaining controversial acupoints, demanding active research in the future. This will enhance the reproducibility and validity of acupuncture studies. It will also lead to a better understanding of acupuncture mechanisms in order to optimize its clinical efficacy for a range of diseases and syndromes. This book has two parts: General Guidelines for Acupuncture Point Locations and WHO Standard Acupuncture Point Locations. First of all, familiarity with the General Guidelines for Acupuncture Point Locations in this book can help the reader to understand and use the contents of this book in depth. I would like to thank all of the participating experts and scholars for this great work, who have overcome the limits of previous acupuncture references. I also appreciate the dedicated effort and harmonious leadership of Dr Choi Seung-hoon, former Regional Adviser in Traditional Medicine of Western Pacific Office, WHO.

  14. An Emprical Point Error Model for Tls Derived Point Clouds

    Science.gov (United States)

    Ozendi, Mustafa; Akca, Devrim; Topan, Hüseyin

    2016-06-01

    The random error pattern of point clouds has significant effect on the quality of final 3D model. The magnitude and distribution of random errors should be modelled numerically. This work aims at developing such an anisotropic point error model, specifically for the terrestrial laser scanner (TLS) acquired 3D point clouds. A priori precisions of basic TLS observations, which are the range, horizontal angle and vertical angle, are determined by predefined and practical measurement configurations, performed at real-world test environments. A priori precision of horizontal (𝜎𝜃) and vertical (𝜎𝛼) angles are constant for each point of a data set, and can directly be determined through the repetitive scanning of the same environment. In our practical tests, precisions of the horizontal and vertical angles were found as 𝜎𝜃=±36.6𝑐𝑐 and 𝜎𝛼=±17.8𝑐𝑐, respectively. On the other hand, a priori precision of the range observation (𝜎𝜌) is assumed to be a function of range, incidence angle of the incoming laser ray, and reflectivity of object surface. Hence, it is a variable, and computed for each point individually by employing an empirically developed formula varying as 𝜎𝜌=±2-12 𝑚𝑚 for a FARO Focus X330 laser scanner. This procedure was followed by the computation of error ellipsoids of each point using the law of variance-covariance propagation. The direction and size of the error ellipsoids were computed by the principal components transformation. The usability and feasibility of the model was investigated in real world scenarios. These investigations validated the suitability and practicality of the proposed method.

  15. Equilibria, Fixed Points, and Complexity Classes

    CERN Document Server

    Yannakakis, Mihalis

    2008-01-01

    Many models from a variety of areas involve the computation of an equilibrium or fixed point of some kind. Examples include Nash equilibria in games; market equilibria; computing optimal strategies and the values of competitive games (stochastic and other games); stable configurations of neural networks; analysing basic stochastic models for evolution like branching processes and for language like stochastic context-free grammars; and models that incorporate the basic primitives of probability and recursion like recursive Markov chains. It is not known whether these problems can be solved in polynomial time. There are certain common computational principles underlying different types of equilibria, which are captured by the complexity classes PLS, PPAD, and FIXP. Representative complete problems for these classes are respectively, pure Nash equilibria in games where they are guaranteed to exist, (mixed) Nash equilibria in 2-player normal form games, and (mixed) Nash equilibria in normal form games with 3 (or ...

  16. Digital microwave communication engineering point-to-point microwave systems

    CERN Document Server

    Kizer, George

    2013-01-01

    The first book to cover all engineering aspects of microwave communication path design for the digital age Fixed point-to-point microwave systems provide moderate-capacity digital transmission between well-defined locations. Most popular in situations where fiber optics or satellite communication is impractical, it is commonly used for cellular or PCS site interconnectivity where digital connectivity is needed but not economically available from other sources, and in private networks where reliability is most important. Until now, no book has adequately treated all en

  17. Robot positioning based on point-to-point motion capability

    Energy Technology Data Exchange (ETDEWEB)

    Park, Y. S.; Cho, H. S.; Koh, K. C.

    2000-03-20

    This paper presents an optimal search method for determining the base location of a robot manipulator so that the robot can have a designated point-to-point (PTP) motion capabilities. Based on the topological characterization of the manipulator workspace and the definitions of various p-connectivity, a computational method is developed for enumerating various PTP motion capabilities into quantitative cost functions. Then an unconstrained search by minimizing the cost function yields the task feasible location of the robot base. This methodology is useful for placement of mobile manipulators and robotic workcell layout design.

  18. April 2004 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data (Geodetic Coordinates) from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs)...

  19. December 2002 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data (latitude and longitude) from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs)...

  20. March 2003 Lidar Point Data of Southern California Coastline: Dana Point to Point La Jolla

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains lidar point data (Geodetic Coordinates) from a strip of Southern California coastline (including water, beach, cliffs, and top of cliffs)...

  1. GRATIS: Pointing and Tracking System

    Science.gov (United States)

    Seiffert, M. D.; Lubin, P. M.; Craig, W. W.; McLean, R.; Harrison, F.

    1992-12-01

    The Gamma-Ray Arc Minute Telescope Imaging System (GRATIS; see companion paper by Harrison et al.) requires a balloon-borne stabilized platform capable of 20 arc second absolute pointing accuracy. We have developed a system which uses computer-based inertial-guidance control of an azimuth-elevation pointing mechanism for the telescope. An innovative computer-based star pattern recognition system automatically generates drift corrections from an image acquired by a Peltier cooled CCD camera. The inertial guidance system provides three axis pointing information with approximately 12 arc seconds precision. This is a true inertial guidance system with gyros, accelerometers, and an integral navigational processor. The gyros have high relative pointing precision, but a slow drift component degrades their absolute accuracy. Control of the elevation position is accomplished through a torque motor that is directly coupled to the telescope. Azimuth control is accomplished through an active zero-stiction bearing at the top of the gondola and a reaction wheel at the bottom. The pointing system has been fully constructed and tested and has been mated with the telescope. We present the results of an extensive series of tracking tests.

  2. Economische analyse van de Nederlandse biotechnologiesector

    OpenAIRE

    Giessen, A.M. van der; Gijsbers, G.W.; Koops, R.; Zee, F.A. van der

    2014-01-01

    In opdracht van de Commissie Genetische Modificatie (COGEM) heeft TNO een deskstudie uitgevoerd getiteld “Economische analyse van de Nederlandse biotechnologiesector”. Deze analyse is één van de voorstudies die de COGEM laat uitvoeren als voorbereiding op de Trendanalyse Biotechnologie, die naar verwachting in 2015 zal worden uitgevoerd. Voor deze analyse heeft de COGEM aan TNO gevraagd ontwikkelingen, trends en kansen van de biotechnologie opnieuw in kaart te brengen, met een nadruk op econo...

  3. [Anne Arold. Kontrastive Analyse...] / Paul Alvre

    Index Scriptorium Estoniae

    Alvre, Paul, 1921-2008

    2001-01-01

    Arvustus: Arold, Anne. Kontrastive analyse der Wortbildungsmuster im Deutschen und im Estnischen (am Beispiel der Aussehensadjektive). Tartu, 2000. (Dissertationes philologiae germanicae Universitatis Tartuensis)

  4. Extracting Feature Curves on Point Sets

    OpenAIRE

    X. F. Pang; Pang, M.Y.; Song, Z.(Central China Normal University, Wuhan, China)

    2011-01-01

    We present an effective algorithm for detecting feature curves on point sets. Based on the local surface fitting method, our algorithm first compute the curvatures and principal directions of each point of point sets. The algorithm then extracts potential feature points according to the biggist principal curvature of the point, and evaluates the principal directions of the detected points. By projecting the points onto the principal axes of their neighborhoods, the potential feature points ar...

  5. Point mass Cosmological Black Holes

    CERN Document Server

    Firouzjaee, Javad T

    2016-01-01

    Real black holes in the universe are located in the expanding accelerating background which are called the cosmological black holes. Hence, it is necessary to model these black holes in the cosmological background where the dark energy is the dominant energy. In this paper, we argue that most of the dynamical cosmological black holes can be modeled by point mass cosmological black holes. Considering the de Sitter background for the accelerating universe, we present the point mass cosmological background in the cosmological de Sitter space time. Our work also includes the point mass black holes which have charge and angular momentum. We study the mass, horizons, redshift structure and geodesics properties for these black holes.

  6. Remotely Sensed Ground Control Points

    Science.gov (United States)

    Hummel, P.

    2016-06-01

    Accurate ground control is required to georeferenced airborne and spaceborne images. The production of ortho-photogrammetric data requires ground control that is traditionally provided as Ground Control Points (GCPs) by GNSS measurements in the field. However, it can be difficult to acquire accurate ground control points due to required turn-around time, high costs or impossible access. CompassData, Inc. a specialist in ground control, has expanded its service to deliver Remotely Sensed Ground Control Points (RSGCPs®). TerraSAR-X and TanDEM-X are two satellites with such high accuracy of their orbital positions and SAR data that RSGCPs® can be produced to a sub-meter quality depending on certain parameters and circumstances. The technology and required parameters are discussed in this paper as well as the resulting accuracies.

  7. ATLAS Civil Engineering Point 1

    CERN Multimedia

    Jean-Claude Vialis

    1999-01-01

    ATLAS Civil Engineering - Point 1 In the film you can see various stages of construction in Point 1: that is the experiment zone for ATLAS experimentation. One part of the video is filmed on the surface of Point 1. Therefore you can get the view of the hall SX 1 and the cranes. Cranes are located close to the ridge of the hall roof. The film gives you the view of the hall that covers the caps and the wells to underground cavern where the experiment will be implemented. The machinery for excavation lifts and cranes as well as the stock areas can also be seen. There are iron mounting and concrete works too

  8. Comparative Analyses Of Multi-Frequency PSI Ground Deformation Measurements

    Science.gov (United States)

    Duro, Javier; Sabater, Jose R.; Albiol, David; Koudogbo, Fifame N.; Arnaud, Alain

    2012-01-01

    In recent years many new developments have been made in the field of SAR image analysis. The wider diversity of available SAR imagery gives the possibility of covering wide ranges of applications in the domain of ground motion monitoring for risk management and damage assessment. The work proposed is based on the evaluation of differences in ground deformation measurements derived from multi-frequency PSI analyses. The objectives of the project are the derivation of rules and the definition of criteria for the selection of the appropriate SAR sensor for a particular type of region of interest. Key selection factors are the satellite characteristics (operating frequency, spatial resolution, and revisit time), the geographic localization of AOI, the land cover type and the extension of the monitoring period. All presented InSAR analyses have been performed using the Stable Point Network (SPN) PSI software developed by Altamira Information [1].

  9. Tipping Points in Texas Rivers

    Science.gov (United States)

    Phillips, Jonathan

    2016-04-01

    Anticipating geomorphic tipping points requires that we learn from the past. Major geomorphic changes in coastal plain rivers of Texas resulting in river metamorphosis or regime shifts were identified, and the major driving factors determined. Nine fluvial tipping points were identified from contemporary observations, historical records, and Quaternary reconstructions. Two of the tipping points (between general aggrading and degrading valley states) are associated with reversals in a fundamental system control (sea-level). One (stable or aggrading vs. degrading channels) is associated with an abrupt change in sediment supply due to dam construction, and two others (changes from meandering to anastomosing channel patterns, and different anastomosis styles) are similarly related to changes in sediment supply and/or transport capacity, but with additional elements of historical contingency. Three tipping points are related to avulsions. One, from a regime dominated to reoccupation of former channels to one dominated by progradation into flood basins, is driven by progressive long term filling of incised valleys. Another, nodal avulsions, are driven by disturbances associated with tectonics or listric faults. The third, avulsions and related valley metamorphosis in unfilled incised valleys, is due to fundamental dynamical instabilities within the fluvial system. This synthesis and analysis suggests that geomorphic tipping points are sometimes associated with general extrinsic or intrinsic (to the fluvial system) environmental change, independent of any disturbances or instabilities. Others are associated with natural (e.g., tectonic) or human (dams) disturbances, and still others with intrinsic geomorphic instabilities. This suggests that future tipping points will be equally diverse with respect to their drivers.

  10. SharePoint and Scrum

    OpenAIRE

    Spiik, Karl-Johan

    2014-01-01

    SharePoint is a development platform that can be used as such once it has been installed. It is efficient tool to develop especially Intranets and Extranets as well as Internet portals. Scrum is an agile project method that presents what kind of meetings and roles there should be in a project. Scrum leads the development team to design their own work, be visible to customer, and estimate their speed of doing. SharePoint complexity and Scrum method might work together. The thesis introduc...

  11. Isotropic and anisotropic pointing models

    CERN Document Server

    Pál, András; Mészáros, László; Mező, György

    2015-01-01

    This paper describes an alternative approach for generating pointing models for telescopes equipped with serial kinematics, esp. equatorial or alt-az mounts. Our model construction does not exploit any assumption for the underlying physical constraints of the mount, however, one can assign various effects to the respective components of the equations. In order to recover the pointing model parameters, classical linear least squares fitting procedures can be applied. This parameterization also lacks any kind of parametric singularity. We demonstrate the efficiency of this type of model on real measurements with meter-class telescopes where the results provide a root mean square accuracy of 1.5-2 arcseconds.

  12. Fixed-point signal processing

    CERN Document Server

    Padgett, Wayne T

    2009-01-01

    This book is intended to fill the gap between the ""ideal precision"" digital signal processing (DSP) that is widely taught, and the limited precision implementation skills that are commonly required in fixed-point processors and field programmable gate arrays (FPGAs). These skills are often neglected at the university level, particularly for undergraduates. We have attempted to create a resource both for a DSP elective course and for the practicing engineer with a need to understand fixed-point implementation. Although we assume a background in DSP, Chapter 2 contains a review of basic theory

  13. Inflection point inflation and reheating

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Soo-Min; Lee, Hyun Min [Chung-Ang University, Department of Physics, Seoul (Korea, Republic of)

    2016-06-15

    We revisit the inflection point inflation with an extended discussion to large field values and consider the reheating effects on the inflationary predictions. Parametrizing the reheating dynamics in terms of the reheating temperature and the equation of state during reheating, we show how the observationally favored parameter space of inflection point inflation is affected by reheating dynamics. Consequently, we apply the general results to the inflation models with non-minimal coupling, such as the SM Higgs inflation and the B - L Higgs inflation. (orig.)

  14. Inflection point inflation and reheating

    Science.gov (United States)

    Choi, Soo-Min; Lee, Hyun Min

    2016-06-01

    We revisit the inflection point inflation with an extended discussion to large field values and consider the reheating effects on the inflationary predictions. Parametrizing the reheating dynamics in terms of the reheating temperature and the equation of state during reheating, we show how the observationally favored parameter space of inflection point inflation is affected by reheating dynamics. Consequently, we apply the general results to the inflation models with non-minimal coupling, such as the SM Higgs inflation and the B-L Higgs inflation.

  15. Prototyputveckling i SharePoint

    OpenAIRE

    Oscar, Furberg

    2015-01-01

    This report is about intranets and SharePoint. It explains how user’s expectations can affect an implementation of an intranet and what companies want to get out of an intranet. It’s also about risks that may occur when an intranet is developed and how to avoid these problems. SharePoint is a collaborative platform and publishing system from Microsoft that assists developers in the implementation of an intranet. The report covers a project that was intended to showcase the strengths of ShareP...

  16. Detection and analyse of hazardous roads in rural areas

    DEFF Research Database (Denmark)

    Sørensen, Michael

    2003-01-01

    For the last period of 5-10 years the notion "Grey roads" (hazardous roads) has appeared in Danish traffic safety work and improvement of these roads has become a very important part of the traffic safety work in many countries. The problem is, that the notion never has been clearly defined......, and therefore there are no unambiguos methods to point out and analyse "Grey roads". In this article based on a ph.D.-project a method to detecting "Grey roads" is introduced....

  17. Impact of Duality Violations on Spectral Sum Rule Analyses

    CERN Document Server

    Cata, O

    2007-01-01

    Recent sum rule analyses on the two-point correlator have led to significant discrepancies in the values found for the OPE condensates, most dramatically in the dimension eight condensate and to a lesser extent in the dimension six one. Precise knowledge of these condensates is of relevance in kaon decays and therefore it seems mandatory to assess the actual impact of what is commonly neglected in spectral sum rules, most prominently the issue of duality violations. We will explicitly compute them in a toy model and show that they are a priori non-negligible.

  18. Human factors analyses of nuclear power plant incidents

    International Nuclear Information System (INIS)

    Human action plays vital role in occurrence and progression of many nuclear power plant incidents such as occurred in TMI-2 and Chernobyl reactors. Therefore, it is essential for ensuring safety of nuclear facilities to prevent occurrence of human error and to take proper recovery action if it occurs. It is necessary to have deep understanding of causes and mechanism of human error. For this purpose, we analysed operators behavior in seven U.S. nuclear power plant incidents from the view point of human factors. (author)

  19. Bounded Fixed-Point Iteration

    DEFF Research Database (Denmark)

    Nielson, Hanne Riis; Nielson, Flemming

    1992-01-01

    they obtain a quadratic bound. These bounds are shown to be tight. Specializing the case of strict and additive functions to functionals of a form that would correspond to iterative programs they show that a linear bound is tight. This is related to several analyses studied in the literature (including...

  20. Economische analyse van de Nederlandse biotechnologiesector

    NARCIS (Netherlands)

    Giessen, A.M. van der; Gijsbers, G.W.; Koops, R.; Zee, F.A. van der

    2014-01-01

    In opdracht van de Commissie Genetische Modificatie (COGEM) heeft TNO een deskstudie uitgevoerd getiteld “Economische analyse van de Nederlandse biotechnologiesector”. Deze analyse is één van de voorstudies die de COGEM laat uitvoeren als voorbereiding op de Trendanalyse Biotechnologie, die naar ver

  1. New environmental metabarcodes for analysing soil DNA

    DEFF Research Database (Denmark)

    Epp, Laura S.; Boessenkool, Sanne; Bellemain, Eva P.;

    2012-01-01

    Metabarcoding approaches use total and typically degraded DNA from environmental samples to analyse biotic assemblages and can potentially be carried out for any kinds of organisms in an ecosystem. These analyses rely on specific markers, here called metabarcodes, which should be optimized for ta....... The metabarcoding approach has considerable potential for biodiversity screening of modern samples and also as a palaeoecological tool....

  2. Novel Algorithms for Astronomical Plate Analyses

    Indian Academy of Sciences (India)

    Rene Hudec; Lukas Hudec

    2011-03-01

    Powerful computers and dedicated software allow effective data mining and scientific analyses in astronomical plate archives. We give and discuss examples of newly developed algorithms for astronomical plate analyses, e.g., searches for optical transients, as well as for major spectral and brightness changes.

  3. ATLAS: civil engineering Point 1

    CERN Multimedia

    2000-01-01

    The ATLAS experimental area is located in Point 1, just across the main CERN entrance, in the commune of Meyrin. There people are busy to finish the different infrastructures for ATLAS. Real underground video. Nice view from the surface to the cavern from the pit side - all the big machines looked very small. The film has original working sound.

  4. ATLAS Civil Engineering Point 1

    CERN Multimedia

    2000-01-01

    Different phases of realisation to Point 1: zone of the ATLAS experiment 18-10-2000 UX 15 cavern and PX16 15-12-2000 USA 15 - UX 15 concreting the arch 14-02-2001 UX 15 - ancrages, isolation and scaffolding

  5. Fixed points of quantum gravity

    OpenAIRE

    Litim, D.F.(Department of Physics and Astronomy, University of Sussex, Brighton, BN1 9QH, UK)

    2004-01-01

    Euclidean quantum gravity is studied with renormalisation group methods. Analytical results for a non-trivial ultraviolet fixed point are found for arbitrary dimensions and gauge fixing parameter in the Einstein-Hilbert truncation. Implications for quantum gravity in four dimensions are discussed.

  6. ELMs and strike point movements

    NARCIS (Netherlands)

    Solano, E. R.; Jachmich, S.; Villone, F.; Hawkes, N.; Corre, Y.; Alper, B.; Loarte, A.; Pitts, R.A.; Guenther, K.; Korotkov, A.; Stamp, M.; Andrew, P.; Conboy, J.; Bolzonella, T.; Kempenaars, M.; Cenedese, A.; Rachlew, E.

    2008-01-01

    A detailed study of position changes of plasma strike points before and after edge localized modes (ELMs) in JET was carried out. A hypothesis being tested is that in an ELM previously closed edge field lines would open up, releasing plasma current and leading to the formation of a new, smaller sepa

  7. Etiology of myofascial trigger points

    NARCIS (Netherlands)

    Bron, C.; Dommerholt, J.D.

    2012-01-01

    Myofascial pain syndrome (MPS) is described as the sensory, motor, and autonomic symptoms caused by myofascial trigger points (TrPs). Knowing the potential causes of TrPs is important to prevent their development and recurrence, but also to inactivate and eliminate existing TrPs. There is general ag

  8. The planar two point algorithm

    NARCIS (Netherlands)

    O. Booij; Z. Zivkovic

    2009-01-01

    Vision-based localization, mapping and navigation is often performed by searching for corresponding image points and estimating the epipolar geometry. It is known that the possible relative poses of a camera mounted on a mobile robot that moves over a planar ground floor, has two degrees of freedom.

  9. Cost-Benefit Analyses of Transportation Investments

    DEFF Research Database (Denmark)

    Næss, Petter

    2006-01-01

    This paper discusses the practice of cost-benefit analyses of transportation infrastructure investment projects from the meta-theoretical perspective of critical realism. Such analyses are based on a number of untenable ontological assumptions about social value, human nature and the natural......-to-pay investigations. Accepting the ontological and epistemological assumptions of cost-benefit analysis involves an implicit acceptance of the ethical and political values favoured by these assumptions. Cost-benefit analyses of transportation investment projects tend to neglect long-term environmental consequences...... and needs among population groups with a low ability to pay. Instead of cost-benefit analyses, impact analyses evaluating the likely effects of project alternatives against a wide range of societal goals is recommended, with quantification and economic valorisation only for impact categories where this can...

  10. Lidar point cloud and stereo image point cloud fusion

    OpenAIRE

    Basgall, Paul L.

    2013-01-01

    Approved for public release; distribution is unlimited The advent of Light Detection and Ranging (LiDAR) point cloud collection has significantly improved the ability to model the world in precise, fine, three-dimensional details. The objective of this research was to demonstrate accurate, foundation methods for fusing LiDAR data and photogrammetric imagery and their potential for change detection. The scope of the project was to investigate optical image to LiDAR registration methods, foc...

  11. Infeasible-interior-point algorithm for a class of nonmonotone complementarity problems and its computational complexity

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper presents an infeasible-interior-point algorithm for aclass of nonmonotone complementarity problems, and analyses its convergence and computational complexity. The results indicate that the proposed algorithm is a polynomial-time one.

  12. An objective change point analysis of landfalling historical Atlantic hurricane numbers

    CERN Document Server

    Jewson, S; Jewson, Stephen; Penzer, Jeremy

    2006-01-01

    In previous work we have analysed the Atlantic basin hurricane number time-series to identify decadal time-scale change points. We now repeat the analysis but for US landfalling hurricanes. The results are very different.

  13. GEOBIA methods for LiDAR obtained point clouds

    OpenAIRE

    Tomljenović, Ivan

    2012-01-01

    This paper critically analyses the state of the art provided in today’s scientific »market of knowledge« concerning the subject of object delineation from LiDAR obtained 3D point clouds. Such approach became a very popular subject in many scientific fields (forestry, geography, archaeology, etc.). The author will give multiple examples on how other authors deal with object extraction and delineation from 3D point clouds. He will also give a brief introduction and explanation of terms such as ...

  14. Point contacts in encapsulated graphene

    International Nuclear Information System (INIS)

    We present a method to establish inner point contacts with dimensions as small as 100 nm on hexagonal boron nitride (hBN) encapsulated graphene heterostructures by pre-patterning the top-hBN in a separate step prior to dry-stacking. 2- and 4-terminal field effect measurements between different lead combinations are in qualitative agreement with an electrostatic model assuming point-like contacts. The measured contact resistances are 0.5–1.5 kΩ per contact, which is quite low for such small contacts. By applying a perpendicular magnetic field, an insulating behaviour in the quantum Hall regime was observed, as expected for inner contacts. The fabricated contacts are compatible with high mobility graphene structures and open up the field for the realization of several electron optical proposals

  15. Sensing with Superconducting Point Contacts

    Directory of Open Access Journals (Sweden)

    Argo Nurbawono

    2012-05-01

    Full Text Available Superconducting point contacts have been used for measuring magnetic polarizations, identifying magnetic impurities, electronic structures, and even the vibrational modes of small molecules. Due to intrinsically small energy scale in the subgap structures of the supercurrent determined by the size of the superconducting energy gap, superconductors provide ultrahigh sensitivities for high resolution spectroscopies. The so-called Andreev reflection process between normal metal and superconductor carries complex and rich information which can be utilized as powerful sensor when fully exploited. In this review, we would discuss recent experimental and theoretical developments in the supercurrent transport through superconducting point contacts and their relevance to sensing applications, and we would highlight their current issues and potentials. A true utilization of the method based on Andreev reflection analysis opens up possibilities for a new class of ultrasensitive sensors.

  16. Maximum Power Point Regulator System

    Science.gov (United States)

    Simola, J.; Savela, K.; Stenberg, J.; Tonicello, F.

    2011-10-01

    The target of the study done under the ESA contract No.17830/04/NL/EC (GSTP4) for Maximum Power Point Regulator System (MPPRS) was to investigate, design and test a modular power system (a core PCU) fulfilling requirement for maximum power transfer even after a single failure in the Power System by utilising a power concept without any potential and credible single point failure. The studied MPPRS concept is of a modular construction, able to track the MPP individually on each SA sections, maintaining its functionality and full power capability after a loss of a complete MPPR module (by utilizingN+1module).Various add-on DCDC converter topology candidates were investigated and redundancy, failure mechanisms and protection aspects were studied

  17. ATLAS: civil engineering Point 1

    CERN Multimedia

    1998-01-01

    Different phases of the SX 15 realisation to Point 1 : zone of the ATLAS experiment 00:13:43 Realization of the concrete floor 19-10-1998 00:29:26 Putting up the metal rails for the roof 19-10-1998 00:33:42 Road alignment entering to POINT1 and in Bollot wood 27-10-1998 00:41:53 General sight of the buildings in construction Building SX gives the cover for the work at the experiment It is used to shelter the Pit and the work for the underground cavern as well as for covering the ground work with big cranes that allows the lowering of the components belonging to the detector. The hall is also used as a detector part storage and cover during the assembly. It shelters small workshops of mechanics and electronics necessary for the assembly and the maintenance of the ATLAS experiment.

  18. The psychological status of phonological analyses

    Directory of Open Access Journals (Sweden)

    David Eddington

    2015-09-01

    Full Text Available This paper casts doubt on the psychological relevance of many phonological analyses. There are four reasons for this: 1 theoretical adequacy does not necessarily imply psychological significance; 2 most approaches are nonempirical in that they are not subject to potential spatiotemporal falsification; 3 phonological analyses are estab­ lished with little or no recourse to the speakers of the language via experimental psy­ chology; 4 the limited base of evidence which most analyses are founded on is further cause for skepticism.

  19. L’Analyse de discours des Sociologues

    OpenAIRE

    Demailly, Lise

    2013-01-01

    Les sociologues utilisent, comme méthode d'analyse, l'analyse de discours. Des recherches, ici exposées, ont été menées sur cette méthode, ses spécificités et ses apports à la formation aux techniques d'expression (T.E.). Il ressort que le sociologue produit d'abord des discours (par l'entretien et l'observation) puis les analyse, les traite. Ces discours sont difficilement utilisables en T.E. tant ils sont saturés d'enjeux théoriques voire idéologiques.

  20. Histograms and Associated Point Processes

    OpenAIRE

    Jacob, Pierre; Oliveira, Paulo

    1999-01-01

    Non parametric inference for point processes is approached using histograms, which provide a nice tool for the analysis of on-line data. The construction of histograms depend on a sequence of partitions, which we take to be non embedded. This is quite natural in what regards applications, but presents some theoretical problems. On another direction, we drop the usual independence assumption on the sample, replacing it by an association hypothesis. Under this setting, we study t...

  1. Turning points in reactor design

    International Nuclear Information System (INIS)

    This article provides some historical aspects on nuclear reactor design, beginning with PWR development for Naval Propulsion and the first commercial application at Yankee Rowe. Five turning points in reactor design and some safety problems associated with them are reviewed: (1) stability of Dresden-1, (2) ECCS, (3) PRA, (4) TMI-2, and (5) advanced passive LWR designs. While the emphasis is on the thermal-hydraulic aspects, the discussion is also about reactor systems

  2. Turning points in reactor design

    Energy Technology Data Exchange (ETDEWEB)

    Beckjord, E.S.

    1995-09-01

    This article provides some historical aspects on nuclear reactor design, beginning with PWR development for Naval Propulsion and the first commercial application at Yankee Rowe. Five turning points in reactor design and some safety problems associated with them are reviewed: (1) stability of Dresden-1, (2) ECCS, (3) PRA, (4) TMI-2, and (5) advanced passive LWR designs. While the emphasis is on the thermal-hydraulic aspects, the discussion is also about reactor systems.

  3. ATLAS Civil Engineering Point 1

    CERN Multimedia

    Jean-Claude Vialis

    2000-01-01

    Point 1 -the zone for the ATLAS experiment. The film includes various stages of construction, especially from the pit of UX 15. Underground work includes the excavation work of the cavern, demolishing the central pillars and posing the support bars for the pit. The UX 15 - will shelter the detector itself. The cavern is located about 100 m below the surface and it is 53 m long, 30 m wide and 34.90 m high.

  4. Activation and Shielding Analyses in Support of the GUINEVERE Project

    Energy Technology Data Exchange (ETDEWEB)

    Serikov, A.; Fischer, U.; Mercatali, L. [Association FZK-EURATOM, KIT, Forschungszentrum Karlsruhe, P.O. Box 3640, 76021 Karlsruhe (Germany); Baeten, P.; Vittiglio, G. [SCK-CEN, Boeretang 200, B-2400 Mol (Belgium)

    2008-07-01

    The GUINEVERE facility (Generator of Uninterrupted Intense Neutrons at the lead Venus Reactor) must satisfy the nuclear safety criteria required by the Belgian safety authority to be licensed. The radiation dose and activation analyses for the nuclear safety assessment of the GUINEVERE project were performed at FZK. The concerted efforts of several European institutions were concentrated on the development and construction of a subcritical fast lead core based on the Venus water moderated reactor at the SCK-CEN site in Mol, Belgium. A Monte Carlo (MC) MCNP5 model was developed in accordance with the current design of the GUINEVERE fast lead core. The analytical MC method does not work for shielding analysis of the GUINEVERE building because of the large size of the rooms and thick concrete walls and floors. MC variance reduction techniques, such as particles splitting, Russian roulette, and point detectors were therefore applied. The JEFF-3.1 nuclear data library was used for radiation transport calculations. The activation analyses for the lead core and building materials were performed with the FISPACT-2005 inventory code and the EAF-2005 library. The neutron and photon dose rate maps were produced using MCNP track-length estimations, point detectors, and a mesh tally superimposed over the GUINEVERE geometry. The effects of D-D and D-T fusion neutron sources were estimated. (authors)

  5. Consumer brand choice: individual and group analyses of demand elasticity.

    Science.gov (United States)

    Oliveira-Castro, Jorge M; Foxall, Gordon R; Schrezenmaier, Teresa C

    2006-03-01

    Following the behavior-analytic tradition of analyzing individual behavior, the present research investigated demand elasticity of individual consumers purchasing supermarket products, and compared individual and group analyses of elasticity. Panel data from 80 UK consumers purchasing 9 product categories (i.e., baked beans, biscuits, breakfast cereals, butter, cheese, fruit juice, instant coffee, margarine and tea) during a 16-week period were used. Elasticity coefficients were calculated for individual consumers with data from all or only 1 product category (intra-consumer elasticities), and for each product category using all data points from all consumers (overall product elasticity) or 1 average data point per consumer (interconsumer elasticity). In addition to this, split-sample elasticity coefficients were obtained for each individual with data from all product categories purchased during weeks 1 to 8 and 9 to 16. The results suggest that: 1) demand elasticity coefficients calculated for individual consumers purchasing supermarket food products are compatible with predictions from economic theory and behavioral economics; 2) overall product elasticities, typically employed in marketing and econometric research, include effects of interconsumer and intraconsumer elasticities; 3) when comparing demand elasticities of different product categories, group and individual analyses yield similar trends; and 4) individual differences in demand elasticity are relatively consistent across time, but do not seem to be consistent across products. These results demonstrate the theoretical, methodological, and managerial relevance of investigating the behavior of individual consumers.

  6. Inflection-point Higgs Inflation

    CERN Document Server

    Okada, Nobuchika

    2016-01-01

    Inflection-point inflation is an interesting possibility to realize a successful slow-roll inflation when inflation is driven by a single scalar field with its initial value below the Planck mass ($\\phi_I \\lesssim M_{Pl}$). In order for a renormalization group (RG) improved effective $\\lambda \\phi^4$ potential to develop an inflection-point, the quartic coupling $\\lambda(\\phi)$ must exhibit a minimum with an almost vanishing value in its RG evolution, namely $\\lambda(\\phi_I) \\simeq 0$ and $\\beta_{\\lambda}(\\phi_I) \\simeq 0$, where $\\beta_{\\lambda}$ is the beta-function of the quartic coupling. As an example, we consider the minimal gauged $B-L$ extended Standard Model at the TeV scale, where we identify the $B-L$ Higgs field as the inflaton field. For a successful inflection-point inflation, which is consistent with the current cosmological observations, the mass ratios among the $Z^{\\prime}$ gauge boson, the right-handed neutrinos and the $B-L$ Higgs boson are fixed. Our scenario can be tested in the future c...

  7. A fixed-point farrago

    CERN Document Server

    Shapiro, Joel H

    2016-01-01

    This text provides an introduction to some of the best-known fixed-point theorems, with an emphasis on their interactions with topics in analysis. The level of exposition increases gradually throughout the book, building from a basic requirement of undergraduate proficiency to graduate-level sophistication. Appendices provide an introduction to (or refresher on) some of the prerequisite material and exercises are integrated into the text, contributing to the volume’s ability to be used as a self-contained text. Readers will find the presentation especially useful for independent study or as a supplement to a graduate course in fixed-point theory. The material is split into four parts: the first introduces the Banach Contraction-Mapping Principle and the Brouwer Fixed-Point Theorem, along with a selection of interesting applications; the second focuses on Brouwer’s theorem and its application to John Nash’s work; the third applies Brouwer’s theorem to spaces of infinite dimension; and the fourth rests ...

  8. DETECTION OF SLOPE MOVEMENT BY COMPARING POINT CLOUDS CREATED BY SFM SOFTWARE

    Directory of Open Access Journals (Sweden)

    K. Oda

    2016-06-01

    Full Text Available This paper proposes movement detection method between point clouds created by SFM software, without setting any onsite georeferenced points. SfM software, like Smart3DCaputure, PhotoScan, and Pix4D, are convenient for non-professional operator of photogrammetry, because these systems require simply specification of sequence of photos and output point clouds with colour index which corresponds to the colour of original image pixel where the point is projected. SfM software can execute aerial triangulation and create dense point clouds fully automatically. This is useful when monitoring motion of unstable slopes, or loos rocks in slopes along roads or railroads. Most of existing method, however, uses mesh-based DSM for comparing point clouds before/after movement and it cannot be applied in such cases that part of slopes forms overhangs. And in some cases movement is smaller than precision of ground control points and registering two point clouds with GCP is not appropriate. Change detection method in this paper adopts CCICP (Classification and Combined ICP algorithm for registering point clouds before / after movement. The CCICP algorithm is a type of ICP (Iterative Closest Points which minimizes point-to-plane, and point-to-point distances, simultaneously, and also reject incorrect correspondences based on point classification by PCA (Principle Component Analysis. Precision test shows that CCICP method can register two point clouds up to the 1 pixel size order in original images. Ground control points set in site are useful for initial setting of two point clouds. If there are no GCPs in site of slopes, initial setting is achieved by measuring feature points as ground control points in the point clouds before movement, and creating point clouds after movement with these ground control points. When the motion is rigid transformation, in case that a loose Rock is moving in slope, motion including rotation can be analysed by executing CCICP for a

  9. Detection of Slope Movement by Comparing Point Clouds Created by SFM Software

    Science.gov (United States)

    Oda, Kazuo; Hattori, Satoko; Takayama, Toko

    2016-06-01

    This paper proposes movement detection method between point clouds created by SFM software, without setting any onsite georeferenced points. SfM software, like Smart3DCaputure, PhotoScan, and Pix4D, are convenient for non-professional operator of photogrammetry, because these systems require simply specification of sequence of photos and output point clouds with colour index which corresponds to the colour of original image pixel where the point is projected. SfM software can execute aerial triangulation and create dense point clouds fully automatically. This is useful when monitoring motion of unstable slopes, or loos rocks in slopes along roads or railroads. Most of existing method, however, uses mesh-based DSM for comparing point clouds before/after movement and it cannot be applied in such cases that part of slopes forms overhangs. And in some cases movement is smaller than precision of ground control points and registering two point clouds with GCP is not appropriate. Change detection method in this paper adopts CCICP (Classification and Combined ICP) algorithm for registering point clouds before / after movement. The CCICP algorithm is a type of ICP (Iterative Closest Points) which minimizes point-to-plane, and point-to-point distances, simultaneously, and also reject incorrect correspondences based on point classification by PCA (Principle Component Analysis). Precision test shows that CCICP method can register two point clouds up to the 1 pixel size order in original images. Ground control points set in site are useful for initial setting of two point clouds. If there are no GCPs in site of slopes, initial setting is achieved by measuring feature points as ground control points in the point clouds before movement, and creating point clouds after movement with these ground control points. When the motion is rigid transformation, in case that a loose Rock is moving in slope, motion including rotation can be analysed by executing CCICP for a loose rock and

  10. On the deformation analysis of point fields

    NARCIS (Netherlands)

    Velsink, H.

    2015-01-01

    A new approach to determine a multi-point deformation of the earth’s surface or objects upon it, represented by point fields measured in two epochs, is presented. The problem of determining, which points have been deformed, is not approached by testing point-by-point, but by formulating alternative

  11. Anthocyanin analyses of Vaccinium fruit dietary supplements

    Science.gov (United States)

    Vaccinium fruit ingredients within dietary supplements were identified by comparisons with anthocyanin analyses of known Vaccinium profiles (demonstration of anthocyanin fingerprinting). Available Vaccinium supplements were purchased and analyzed; their anthocyanin profiles (based on HPLC separation...

  12. 49 CFR 1180.7 - Market analyses.

    Science.gov (United States)

    2010-10-01

    ... OF TRANSPORTATION RULES OF PRACTICE RAILROAD ACQUISITION, CONTROL, MERGER, CONSOLIDATION PROJECT, TRACKAGE RIGHTS, AND LEASE PROCEDURES General Acquisition Procedures § 1180.7 Market analyses. (a) For... company's marketing plan and existing and potential competitive alternatives (inter- as well as...

  13. Understanding Human Error Based on Automated Analyses

    Data.gov (United States)

    National Aeronautics and Space Administration — This is a report on a continuing study of automated analyses of experiential textual reports to gain insight into the causal factors of human errors in aviation...

  14. Random error in cardiovascular meta-analyses

    DEFF Research Database (Denmark)

    Albalawi, Zaina; McAlister, Finlay A; Thorlund, Kristian;

    2013-01-01

    BACKGROUND: Cochrane reviews are viewed as the gold standard in meta-analyses given their efforts to identify and limit systematic error which could cause spurious conclusions. The potential for random error to cause spurious conclusions in meta-analyses is less well appreciated. METHODS: We...... examined all reviews approved and published by the Cochrane Heart Group in the 2012 Cochrane Library that included at least one meta-analysis with 5 or more randomized trials. We used trial sequential analysis to classify statistically significant meta-analyses as true positives if their pooled sample size...... and/or their cumulative Z-curve crossed the O'Brien-Fleming monitoring boundaries for detecting a RRR of at least 25%. We classified meta-analyses that did not achieve statistical significance as true negatives if their pooled sample size was sufficient to reject a RRR of 25%. RESULTS: Twenty three...

  15. A History of Rotorcraft Comprehensive Analyses

    Science.gov (United States)

    Johnson, Wayne

    2013-01-01

    A history of the development of rotorcraft comprehensive analyses is presented. Comprehensive analyses are digital computer programs that calculate the aeromechanical behavior of the rotor and aircraft, bringing together the most advanced models of the geometry, structure, dynamics, and aerodynamics available in rotary wing technology. The development of the major codes of the last five decades from industry, government, and universities is described. A number of common themes observed in this history are discussed.

  16. Thermal Analyse sof Cross-Linked Polyethylene

    Directory of Open Access Journals (Sweden)

    Radek Polansky

    2007-01-01

    Full Text Available The paper summarizes results obtained during the structural analyses measurements (Differential Scanning Calorimetry DSC, Thermogravimetry TG, Thermomechanical analysis TMA and Fourier transform infrared spectroscopy FT-IR. The samples of cross-linked polyethylene cable insulation were tested via these analyses. The DSC and TG were carried out using simultaneous thermal analyzer TA Instruments SDT Q600 with connection of Fourier transform infrared spectrometer Nicolet 380. Thermomechanical analysis was carried out by TMA Q400EM TA Instruments apparatus.

  17. [Differences between myofascial trigger points and tender points].

    Science.gov (United States)

    Mense, S

    2011-02-01

    The article describes and compares the characteristics of myofascial trigger points (MTrPs) of the myofascial pain syndrome and the tender points (TePs) of the fibromyalgia syndrome. Many statements are hypothetical, because not all aspects of the disorders have been clarified in solid studies. Signs and symptoms of MTrPs: (1) palpable nodule, often located close to the muscle belly, (2) often single, (3) allodynia and hyperalgesia at the MTrP, (4) referral of the MTrP pain, (5) normal pain sensitivity outside the MTrPs, (6) local twitch response, (7) local contracture in biopsy material, (8) peripheral mechanism probable. Signs and symptoms of TePs: (1) no palpable nodule, (2) location often close to the muscle attachments, (3) multiple by definition, (4) allodynia and hyperalgesia also outside the TePs, (5) enhanced pain under psychic stress, (6) unspecific histological changes in biopsy material, (7) central nervous mechanism probable. The multitude of differences speak against a common aetiology and pathophysiology.

  18. Review of ICES sole stock MSY and reference points

    OpenAIRE

    SIMMONDS EDMUND

    2011-01-01

    Meta-analyses, applying generic methods within a species group, have benefits in terms of providing more stable estimates of FMSY reference points and estimates for individual stocks which by themselves may otherwise have insufficient data. Current ICES advice for seven sole stocks for which there is sufficient data gives Fmsy estimates which vary from 0.16 to 0.38, but these are specified for differing age ranges so are not directly comparable. Bpa is estimated for six of thes...

  19. Expected net gain data of low-template DNA analyses.

    Science.gov (United States)

    Gittelson, Simone; Steffen, Carolyn R; Coble, Michael D

    2016-09-01

    Low-template DNA analyses are affected by stochastic effects which can produce a configuration of peaks in the electropherogram (EPG) that is different from the genotype of the DNA׳s donor. A probabilistic and decision-theoretic model can quantify the expected net gain (ENG) of performing a DNA analysis by the difference between the expected value of information (EVOI) and the cost of performing the analysis. This article presents data on the ENG of performing DNA analyses of low-template DNA for a single amplification, two replicate amplifications, and for a second replicate amplification given the result of a first analysis. The data were obtained using amplification kits AmpFlSTR Identifiler Plus and Promega׳s PowerPlex 16 HS, an ABI 3130xl genetic sequencer, and Applied Biosystem׳s GeneMapper ID-X software. These data are supplementary to an original research article investigating whether a forensic DNA analyst should perform a single DNA analysis or two replicate analyses from a decision-theoretic point of view, entitled "Low-template DNA: a single DNA analysis or two replicates?" (Gittelson et al., 2016) [1]. PMID:27331117

  20. Division of Labor in Vocabulary Structure: Insights From Corpus Analyses.

    Science.gov (United States)

    Christiansen, Morten H; Monaghan, Padraic

    2016-07-01

    Psychologists have used experimental methods to study language for more than a century. However, only with the recent availability of large-scale linguistic databases has a more complete picture begun to emerge of how language is actually used, and what information is available as input to language acquisition. Analyses of such "big data" have resulted in reappraisals of key assumptions about the nature of language. As an example, we focus on corpus-based research that has shed new light on the arbitrariness of the sign: the longstanding assumption that the relationship between the sound of a word and its meaning is arbitrary. The results reveal a systematic relationship between the sound of a word and its meaning, which is stronger for early acquired words. Moreover, the analyses further uncover a systematic relationship between words and their lexical categories-nouns and verbs sound differently from each other-affecting how we learn new words and use them in sentences. Together, these results point to a division of labor between arbitrariness and systematicity in sound-meaning mappings. We conclude by arguing in favor of including "big data" analyses into the language scientist's methodological toolbox. PMID:26399384

  1. Analyse of Principles of Corporate Social Responsibility in Food Industry in the Slovak Republic

    OpenAIRE

    Renáta Prokeinová

    2012-01-01

    The aim of the paper analyses the complexity of term corporate social responsibility from historical and present points of view, to deal with individual principles of corporate social responsibility and to map out the present situation in Slovakia. The object of practical part was to analyse the implementation of principles of corporate social responsibility in food industry. The main part is focused on the evaluation of the survey of corporate social responsibility conducted among companies ...

  2. Analyses of steam generator collector rupture for WWER-1000 using Relap5 code

    Energy Technology Data Exchange (ETDEWEB)

    Balabanov, E.; Ivanova, A. [Energoproekt, Sofia (Bulgaria)

    1995-12-31

    The paper presents some of the results of analyses of an accident with a LOCA from the primary to the secondary side of a WWER-1000/320 unit. The objective of the analyses is to estimate the primary coolant to the atmosphere, to point out the necessity of a well defined operator strategy for this type of accident as well as to evaluate the possibility to diagnose the accident and to minimize the radiological impact on the environment.

  3. Atlantic NAD 83 SLA Baseline Points

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains baseline points in ArcGIS shapefile format for the BOEM Atlantic Region. Baseline points are the discrete coordinate points along the...

  4. Point-point and point-line moving-window correlation spectroscopy and its applications

    Science.gov (United States)

    Zhou, Qun; Sun, Suqin; Zhan, Daqi; Yu, Zhiwu

    2008-07-01

    In this paper, we present a new extension of generalized two-dimensional (2D) correlation spectroscopy. Two new algorithms, namely point-point (P-P) correlation and point-line (P-L) correlation, have been introduced to do the moving-window 2D correlation (MW2D) analysis. The new method has been applied to a spectral model consisting of two different processes. The results indicate that P-P correlation spectroscopy can unveil the details and re-constitute the entire process, whilst the P-L can provide general feature of the concerned processes. Phase transition behavior of dimyristoylphosphotidylethanolamine (DMPE) has been studied using MW2D correlation spectroscopy. The newly proposed method verifies that the phase transition temperature is 56 °C, same as the result got from a differential scanning calorimeter. To illustrate the new method further, a lysine and lactose mixture has been studied under thermo perturbation. Using the P-P MW2D, the Maillard reaction of the mixture was clearly monitored, which has been very difficult using conventional display of FTIR spectra.

  5. The Point Lepreau Desktop Simulator

    International Nuclear Information System (INIS)

    The Point Lepreau Desktop Simulator runs plant process modeling software on a 266 MHz single CPU DEC Alpha computer. This same Alpha also runs the plant control computer software on an SSCI 125 emulator. An adjacent Pentium PC runs the simulator's Instructor Facility software, and communicates with the Alpha through an Ethernet. The Point Lepreau Desktop simulator is constructed to be as similar as possible to the Point Lepreau full scope training simulator. This minimizes total maintenance costs and enhances the benefits of the desktop simulator. Both simulators have the same modeling running on a single CPU in the same schedule of calculations. Both simulators have the same Instructor Facility capable of developing and executing the same lesson plans, doing the same monitoring and control of simulations, inserting all the same malfunctions, performing all the same overrides, capable of making and restoring all the same storepoints. Both simulators run the same plant control computer software - the same assembly language control programs as the power plant uses for reactor control, heat transport control, annunciation, etc. This is a higher degree of similarity between a desktop simulator and a full scope training simulator than previously reported for a computer controlled nuclear plant. The large quantity of control room hardware missing from the desktop simulator is replaced by software. The Instructor Facility panel override software of the training simulator provides the means by which devices (switches, controllers, windows, etc.) on the control room panels can be controlled and monitored in the desktop simulator. The CRT of the Alpha provides a mouse operated DCC keyboard mimic for controlling the plant control computer emulation. Two emulated RAMTEK display channels appear as windows for monitoring anything of interest on plant DCC displays, including one channel for annunciation. (author)

  6. Discontinuous dynamics with grazing points

    Science.gov (United States)

    Akhmet, M. U.; Kıvılcım, A.

    2016-09-01

    Discontinuous dynamical systems with grazing solutions are discussed. The group property, continuation of solutions, continuity and smoothness of solutions are thoroughly analyzed. A variational system around a grazing solution which depends on near solutions is constructed. Orbital stability of grazing cycles is examined by linearization. Small parameter method is extended for analysis of grazing orbits, and bifurcation of cycles is observed in an example. Linearization around an equilibrium grazing point is discussed. The results can be extended on functional differential equations, partial differential equations and others. Appropriate illustrations are depicted to support the theoretical results.

  7. Emergent physics: Fermi point scenario

    CERN Document Server

    Volovik, G E

    2008-01-01

    The Fermi-point scenario of emergent gravity has the following consequences: gravity emerges together with fermionic and bosonic matter; emergent fermionic matter consists of massless Weyl fermions; emergent bosonic matter consists of gauge fields; Lorentz symmetry persists well above the Planck energy; space-time is naturally 4-dimensional; Universe is naturally flat; cosmological constant is naturally small or zero; underlying physics is based on discrete symmetries; `quantum gravity' cannot be obtained by quantization of Einstein equations; there is no contradiction between quantum mechanics and gravity; etc.

  8. Pointing and Morality in Chicago

    OpenAIRE

    McNeill, David

    1998-01-01

    The signature form of abstract deixis is the classic pointing G-hand aimed at absolutely nothing. This gesture is extremely widespread and frequent in conversational discourse.[2] A speaker says "and there was [this guy]", and flexes an index finger at a certain locus, although there is no person there. In effect, the gesture `creates' a reference, in this case an imaginary person identified as "this guy". What I am terming `abstract deixis' is, according to Bühler (1982), concrete deixis tha...

  9. ULS LiDAR SUPPORTED ANALYSES OF LASER BEAM PENETRATION FROM DIFFERENT ALS SYSTEMS INTO VEGETATION

    OpenAIRE

    Wieser, M.; Hollaus, M.; G. Mandlburger; Glira, P.; Pfeifer, N

    2016-01-01

    This study analyses the underestimation of tree and shrub heights for different airborne laser scanner systems and point cloud distribution within the vegetation column. Reference data was produced by a novel UAV-borne laser scanning (ULS) with a high point density in the complete vegetation column. With its physical parameters (e.g. footprint) and its relative accuracy within the block as stated in Section 2.2 the reference data is supposed to be highly suitable to detect the highes...

  10. Modelling point patterns with linear structures

    DEFF Research Database (Denmark)

    Møller, Jesper; Rasmussen, Jakob Gulddahl

    2009-01-01

    Many observed spatial point patterns contain points placed roughly on line segments. Point patterns exhibiting such structures can be found for example in archaeology (locations of bronze age graves in Denmark) and geography (locations of mountain tops). We consider a particular class of point pr...... consider simulations of this model and compare with real data.......Many observed spatial point patterns contain points placed roughly on line segments. Point patterns exhibiting such structures can be found for example in archaeology (locations of bronze age graves in Denmark) and geography (locations of mountain tops). We consider a particular class of point...

  11. Modelling point patterns with linear structures

    DEFF Research Database (Denmark)

    Møller, Jesper; Rasmussen, Jakob Gulddahl

    Many observed spatial point patterns contain points placed roughly on line segments. Point patterns exhibiting such structures can be found for example in archaeology (locations of bronze age graves in Denmark) and geography (locations of mountain tops). We consider a particular class of point pr...... consider simulations of this model and compare with real data.......Many observed spatial point patterns contain points placed roughly on line segments. Point patterns exhibiting such structures can be found for example in archaeology (locations of bronze age graves in Denmark) and geography (locations of mountain tops). We consider a particular class of point...

  12. Isolation and Characterization of a C-repeat Binding Transcription Factor from Maize

    Institute of Scientific and Technical Information of China (English)

    Lei Wang; Yanzhong Luo; Lan Zhang; Jun Zhao; Zhiqiu Hu; Yunliu Fan; Chunyi Zhang

    2008-01-01

    C-repeat binding proteins (CBFs) are a group of transcription factors that have been proven to be important for stress tolerance in plants.Many of these transcription factors transactivate the promoters of cold-regulated genes via binding to low temperature- or dehydration-responsive cis-elements,thus conferring plants cold acclimation.In the present study,we Isolated a C-repeat binding transcription factor from maize using the yeast one-hybrid system with the C-repeat motif from the promoter of the Arabidopsis COR15a gene as bait.The isolated transcription factor is highly similar to the Arabidopsis CBF3 in their predicted amino acid sequences,and is therefore designated ZmCBF3.Point mutation analyses of the ZmCBF3-binding cis-element revealed (A/G)(C/T)CGAC as the core binding sequence.Expression analyses showed that ZmCBF3 was upregulated by both abscisic acid and low temperature,and was actively expressed during embryogenesis,suggesting that ZmCBF3 plays a role in stress response in maize.

  13. Good Points for Diophantine Approximation

    Indian Academy of Sciences (India)

    Daniel Berend; Artūras Dubickas

    2009-09-01

    Given a sequence $(x_n)^∞_{n=1}$ of real numbers in the interval [0,1) and a sequence $(_n)^∞_{n=1}$ of positive numbers tending to zero, we consider the size of the set of numbers in [0,1] which can be `well approximated’ by terms of the first sequence, namely, those $y\\in[0,1]$ for which the inequality $|y-x_n| < _n$ holds for infinitely many positive integers . We show that the set of `well approximable’ points by a sequence $(x_n)^∞_{n=1}$, which is dense in [0,1], is `quite large’ no matter how fast the sequence $(_n)^∞_{n=1}$ converges to zero. On the other hand, for any sequence of positive numbers $(_n)^∞_{n=1}$ tending to zero, there is a well distributed sequence $(x_n)^∞_{n=1}$ in the interval [0,1] such that the set of `well approximable’ points is `quite small’.

  14. Algebraic points on meromorphic curves

    CERN Document Server

    Herblot, Mathilde

    2012-01-01

    The classic Schneider-Lang theorem in transcendence theory asserts that there are only finitely many points at which algebraically independent complex meromorphic functions of finite order of growth can simultaneously take values in a number field, when satisfying a polynomial differential equation with coefficients in this given number field. In this article, we are interested in generalizing this theorem in two directions. First, instead of considering meromorphic functions on C we consider holomorphic maps on an affine curve over the field C or C_p. This extends a statement of D. Bertrand, which applies to meromorphic functions on P^1(C) or P^1(C_p) minus a finite subset of points. Secondly, we deal with algebraic values taken by the functions, instead of rational values as in the classic setting, inspired by a work of D. Bertrand. We prove a geometric statement extending those two results, using the slopes method, written in the language of Arakelov geometry. In the complex case, we recover a special case...

  15. Processing Terrain Point Cloud Data

    KAUST Repository

    DeVore, Ronald

    2013-01-10

    Terrain point cloud data are typically acquired through some form of Light Detection And Ranging sensing. They form a rich resource that is important in a variety of applications including navigation, line of sight, and terrain visualization. Processing terrain data has not received the attention of other forms of surface reconstruction or of image processing. The goal of terrain data processing is to convert the point cloud into a succinct representation system that is amenable to the various application demands. The present paper presents a platform for terrain processing built on the following principles: (i) measuring distortion in the Hausdorff metric, which we argue is a good match for the application demands, (ii) a multiscale representation based on tree approximation using local polynomial fitting. The basic elements held in the nodes of the tree can be efficiently encoded, transmitted, visualized, and utilized for the various target applications. Several challenges emerge because of the variable resolution of the data, missing data, occlusions, and noise. Techniques for identifying and handling these challenges are developed. © 2013 Society for Industrial and Applied Mathematics.

  16. Material-Point Analysis of Large-Strain Problems

    DEFF Research Database (Denmark)

    Andersen, Søren

    , it is possible to predict if a certain slope is stable using commercial finite element or finite difference software such as PLAXIS, ABAQUS or FLAC. However, the dynamics during a landslide are less explored. The material-point method (MPM) is a novel numerical method aimed at analysing problems involving......The aim of this thesis is to apply and improve the material-point method for modelling of geotechnical problems. One of the geotechnical phenomena that is a subject of active research is the study of landslides. A large amount of research is focused on determining when slopes become unstable. Hence...... materials subjected to large strains in a dynamical time–space domain. This thesis explores the material-point method with the specific aim of improving the performance for geotechnical problems. Large-strain geotechnical problems such as landslides pose a major challenge to model numerically. Employing...

  17. Multiple tipping points and optimal repairing in interacting networks

    Science.gov (United States)

    Majdandzic, Antonio; Braunstein, Lidia A.; Curme, Chester; Vodenska, Irena; Levy-Carciente, Sary; Eugene Stanley, H.; Havlin, Shlomo

    2016-03-01

    Systems composed of many interacting dynamical networks--such as the human body with its biological networks or the global economic network consisting of regional clusters--often exhibit complicated collective dynamics. Three fundamental processes that are typically present are failure, damage spread and recovery. Here we develop a model for such systems and find a very rich phase diagram that becomes increasingly more complex as the number of interacting networks increases. In the simplest example of two interacting networks we find two critical points, four triple points, ten allowed transitions and two `forbidden' transitions, as well as complex hysteresis loops. Remarkably, we find that triple points play the dominant role in constructing the optimal repairing strategy in damaged interacting systems. To test our model, we analyse an example of real interacting financial networks and find evidence of rapid dynamical transitions between well-defined states, in agreement with the predictions of our model.

  18. Freezing point depression in model Lennard-Jones solutions

    Science.gov (United States)

    Koschke, Konstantin; Jörg Limbach, Hans; Kremer, Kurt; Donadio, Davide

    2015-09-01

    Crystallisation of liquid solutions is of uttermost importance in a wide variety of processes in materials, atmospheric and food science. Depending on the type and concentration of solutes the freezing point shifts, thus allowing control on the thermodynamics of complex fluids. Here we investigate the basic principles of solute-induced freezing point depression by computing the melting temperature of a Lennard-Jones fluid with low concentrations of solutes, by means of equilibrium molecular dynamics simulations. The effect of solvophilic and weakly solvophobic solutes at low concentrations is analysed, scanning systematically the size and the concentration. We identify the range of parameters that produce deviations from the linear dependence of the freezing point on the molal concentration of solutes, expected for ideal solutions. Our simulations allow us also to link the shifts in coexistence temperature to the microscopic structure of the solutions.

  19. Critical-point analysis of the liquid-vapor interfacial surface tension

    Science.gov (United States)

    Salvino, R. E.

    1990-01-01

    The interfacial surface tension of the liquid-vapor system is analyzed near the critical point in a manner similar to bulk thermodynamic critical-point analyses. This is accomplished by a critical-point analysis of the single-phase hard-wall surface tension. Both a Landau expansion and a scaling theory equation of state are investigated. Some general exponent relations are derived and, in addition, some thermodynamically defined correlation lengths are discussed.

  20. Extracting Feature Curves on Point Sets

    Directory of Open Access Journals (Sweden)

    X. F. Pang

    2011-06-01

    Full Text Available We present an effective algorithm for detecting feature curves on point sets. Based on the local surface fitting method, our algorithm first compute the curvatures and principal directions of each point of point sets. The algorithm then extracts potential feature points according to the biggist principal curvature of the point, and evaluates the principal directions of the detected points. By projecting the points onto the principal axes of their neighborhoods, the potential feature points are smoothed. Using the principal directions with each optimized point, feature curves are generated by polyline growing along the principal directions of feature points. The results indicate that our algorithm is sensitive to both sharp and smooth feature curves of point set, and it supports multi-resolution extraction of features.

  1. Possible refurbishment of Point Lepreau

    International Nuclear Information System (INIS)

    In February 2000, the NB Power Board of Directors approved Phase one of a project to produce a business case including a detailed scope and estimate associated with the possible refurbishment of the Point Lepreau Generating Station (PLGS). The Preliminary plan for refurbishment projects an 18-month outage starting as early as the spring of 2006. If the station were to be refurbished, then it would be run for another 25 to 30 years. The decision on whether or not to refurbish PLGS has not been made and is not expected until the summer of 2002. The results of the first phase of the project will be used to prepare a detailed business case that will be presented to the NB Power board of directors in January of 2002. At that time a decision will be made as to whether to refurbish the unit, or obtain other means of replacing the energy produced by PLGS. The station currently produces about a third of the power generated within the province. If the business case is approved, all-380 Pressure Tubes and Calandria Tubes, along with their related End Fittings and Feeders would be replaced. This material would be stored in new storage vaults to be constructed at the existing on-site Waste Management Facility. Replacement of other station components will be performed as required, as determined from the results of a comprehensive Plant Condition Assessment. The condition assessments build on work done under the Plant Life Management Program. Point Lepreau Generating Station has operated well since start of commercial operation in early 1983. With a lifetime capacity factor of about 84% (up to the end of 2000), it has proven to be an economic and environmentally sound electricity provider. The station has also had a significant positive economic impact in Southern New Brunswick, employing over 600 people. However the Pressure Tubes and Feeders are nearing the point in time in which they will exceed their fitness for service criteria. Although tubes can be replaced on an

  2. Identifying, analysing and solving problems in practice.

    Science.gov (United States)

    Hewitt-Taylor, Jaqui

    When a problem is identified in practice, it is important to clarify exactly what it is and establish the cause before seeking a solution. This solution-seeking process should include input from those directly involved in the problematic situation, to enable individuals to contribute their perspective, appreciate why any change in practice is necessary and what will be achieved by the change. This article describes some approaches to identifying and analysing problems in practice so that effective solutions can be devised. It includes a case study and examples of how the Five Whys analysis, fishbone diagram, problem tree analysis, and Seven-S Model can be used to analyse a problem.

  3. TOGGLE: toolbox for generic NGS analyses

    OpenAIRE

    Monat, Cécile; Tranchant-Dubreuil, Christine; Kougbeadjo, Ayité; Farcy , Cédric; Ortega-Abboud, Enrique; Amanzougarene, Souhila; Ravel, Sébastien; Agbessi, Mawusse; Orjuela-Bouniol, Julie; Summo, Marilyne; Sabot, François

    2015-01-01

    Background: The explosion of NGS (Next Generation Sequencing) sequence data requires a huge effort in Bioinformatics methods and analyses. The creation of dedicated, robust and reliable pipelines able to handle dozens of samples from raw FASTQ data to relevant biological data is a time-consuming task in all projects relying on NGS. To address this, we created a generic and modular toolbox for developing such pipelines. Results: TOGGLE (TOolbox for Generic nGs anaLysEs) is a suite of tools abl...

  4. Analyse de discours et demande sociale

    OpenAIRE

    Cislaru, Georgeta; Garnier, Sylvie; Matras, Marie-Thérèse; Pugnière-Saavedra, Frédéric; Rousseau, Patrick; Sitri, Frédérique; Veniard, Marie

    2010-01-01

    Que peut nous révéler l’analyse de discours des pratiques sociétales et des pratiques discursives qui les sous-tendent ? En questionnant le discours,l'analyse de discours questionne aussi ses instances productrices : instances politiques, médiatiques, institutionnelles. Elle a ainsi engagé, depuis une quarantaine d’années, un dialogue interdisciplinaire fructueux. Avec cinq contributions d’analystes de discours et deux de professionnels de la protection de l’enfance, ce numéro des Carnets du ...

  5. TOGGLE: toolbox for generic NGS analyses

    OpenAIRE

    Monat, Cécile; Tranchant-Dubreuil, Christine; Kougbeadjo, Ayité; Farcy, Cédric; Ortega-Abboud, Enrique; Amanzougarene, Souhila; Ravel, Sébastien; Agbessi, Mawusse; Orjuela-Bouniol , Julie; Summo, Marilyne; Sabot, François

    2015-01-01

    Background The explosion of NGS (Next Generation Sequencing) sequence data requires a huge effort in Bioinformatics methods and analyses. The creation of dedicated, robust and reliable pipelines able to handle dozens of samples from raw FASTQ data to relevant biological data is a time-consuming task in all projects relying on NGS. To address this, we created a generic and modular toolbox for developing such pipelines. Results TOGGLE (TOolbox for Generic nGs anaLysEs) is a suite of tools able ...

  6. Prosjektering og analyse av en spennarmert betongbru

    OpenAIRE

    Strand, Elin Holsten; Kaldbekkdalen, Ann-Kristin

    2014-01-01

    Hensikten med rapporten er å gjennomføre analyse og dimensjonering av en etteroppspent betongbru. Modellering og analyse er gjennomført i NovaFrame 5. En del av oppgaven var å bestemme spennsystem og tverrsnittshøyden i brua. Det ble antatt seks spennkabler i felt, og tolv over støtte. Videre ble tverrsnittshøyden satt lik 1,3 meter. Dimensjoneringen ble gjennomført i henhold til gjeldende Eurokoder, aktuelle dokumenter og Håndbok 185, som er utarb...

  7. The application analyses for primary spectrum pyrometer

    Institute of Scientific and Technical Information of China (English)

    FU; TaiRan

    2007-01-01

    In the applications of primary spectrum pyrometry, based on the dynamic range and the minimum sensibility of the sensor, the application issues, such as the measurement range and the measurement partition, were investigated through theoretical analyses. For a developed primary spectrum pyrometer, the theoretical predictions of measurement range and the distributions of measurement partition were presented through numerical simulations. And the measurement experiments of high-temperature blackbody and standard temperature lamp were processed to further verify the above theoretical analyses and numerical results. Therefore the research in the paper provides the helpful supports for the applications of primary spectrum pyrometer and other radiation pyrometers.……

  8. A theoretical framework for analysing preschool teaching

    DEFF Research Database (Denmark)

    Chaiklin, Seth

    2014-01-01

    This article introduces a theoretical framework for analysing preschool teaching as a historically-grounded societal practice. The aim is to present a unified framework that can be used to analyse and compare both historical and contemporary examples of preschool teaching practice within and across...... national traditions. The framework has two main components, an analysis of preschool teaching as a practice, formed in relation to societal needs, and an analysis of the categorical relations which necessarily must be addressed in preschool teaching activity. The framework is introduced and illustrated...... teaching as a practice....

  9. Interferences in reactor neutron activation analyses

    International Nuclear Information System (INIS)

    It has been shown that interfering reactions may occur in neutron activation analyses of aluminum and zinc matrixes, commonly used in nuclear areas. The interferences analysed were: Al2713 (n, α) Na2411 and Zn6430 (n, p) Cu6429. The method used was the non-destructive neutron activation analysis and the spectra were obtained in a 1024 multichannel system coupled with a Ge(Li) detector. Sodium was detected in aluminum samples from the reactor tank and pneumatic transfer system. The independence of the sodium concentration in samples in the range of 0 - 100 ppm is shown by the attenuation obtained with the samples encapsulated in cadmium. (Author)

  10. Retracts, fixed point property and existence of periodic points

    Institute of Scientific and Technical Information of China (English)

    MAI; Jiehua(

    2001-01-01

    [1]Sarkovskii, A. N. , Coexistence of cycles of a continuous map of a line into itself, Ukrain. Mat. Z. , 1964, 16(1): 61-71.[2]Li, T. Y., Misiurewicz, M., Pianigiani, G. et al., No division implies chaos, Trans. Amer. Math. Soc., 1982, 273(1):191-199.[3]Mai Jiehua, Multi-separation, centrifugality and centripetality imply chaos, Trans. Amer. Math. Soc., 1999, 351 (1):343-351.[4]Block, L., Coppel, W., Dynamics in One Dimension, Berlin, New York: Springer-Verlag, 1992.[5]Misiurewicz, M., Periodic points of maps of degree one of a circle, Ergod. Th. & Dynam. Sys. , 1982, 2(2): 221-227.[6]Alseda, L., Llibre, J., Misiurewicz, M., Periodic orbits of maps of Y, Trans. Amer. Math. Soc., 1989, 313(2): 475-538.[7]Baldwin, S. , An extension of Sarkovskii's theorem to the n-od, Ergod. Th. & Dynam. Sys. , 1991, 11(2): 249-271.[8]Alseda, L. , Ye, X. D. , No division and the set of periods for tree maps, Ergod. Th. & Dynam. Sys., 1995, 15(2): 221-237.[9]Leseduarte, M. C., Llibre, J., On the set of periods for σ maps, Trans. Amer. Math. Soc., 1995, 347(12): 4899-4942.[10]Armstrong, M. A., Basic Topology, New York: Springer-Verlag, 1983.[11]Dicks, W. , Llibre, J. , Orientation-preserving self-homeomorphisms of the surface of genus two have points of period at most two, Proc. Amer. Math. Soc., 1996, 124(5): 1583-1591.[12]Kolev, B., Peroueme, M. C., Recurrent surface homeonorphisms, Math. Proc. Camb. Phil. Soc., 1998, 124(1): 161-168.[13]Franks, J., Generalizations of the Poincare-Birkhoff theorem, Ann. Math., 1988, 128(1): 139-151.[14]Hall, G. R. , Some problems on dynamics of annulus maps, Contemporary Mathematics, 1988, 81(1): 135-152.[15]Barge, M., Matison, T., A Poincare-Birkhoff theorem on invariant plane continua, Ergod. Th. & Dynam. Sys., 1998, 18(1): 41-52.[16]Munkres, J. Pt., Topology, Englewood Cliffs: Prentice-Hall, 1975.

  11. Chiral exceptional points in metasurfaces

    Science.gov (United States)

    Kang, Ming; Chen, Jing; Chong, Y. D.

    2016-09-01

    An exceptional point (EP) is a degeneracy occurring in a non-energy-conserving system, in which two eigenvectors of a non-Hermitian Hamiltonian coalesce. We explore how EPs can be realized in a metamaterial surface, or metasurface, consisting of a pair of lossy coupled linear antennas in each unit cell. EPs appear in the eigenvectors of the transmission matrix by tuning the frequency and the coupling and loss rates of the metasurface. Each EP is associated with the appearance of a circularly polarized transmission eigenstate; hence, within the parameter space of the system, the EPs lie along pairs of curves with distinct chirality. Our results are obtained using finite-difference time-domain simulations, as well as a fitted coupled-mode theory. The coupled-mode theory agrees well with the numerical results and is capable of accurately predicting the EP f curves.

  12. Fixed Point and Aperiodic Tilings

    CERN Document Server

    Durand, Bruno; Shen, Alexander

    2008-01-01

    An aperiodic tile set was first constructed by R.Berger while proving the undecidability of the domino problem. It turned out that aperiodic tile sets appear in many topics ranging from logic (the Entscheidungsproblem) to physics (quasicrystals) We present a new construction of an aperiodic tile set that is based on Kleene's fixed-point construction instead of geometric arguments. This construction is similar to J. von Neumann self-reproducing automata; similar ideas were also used by P. Gacs in the context of error-correcting computations. The flexibility of this construction allows us to construct a ``robust'' aperiodic tile set that does not have periodic (or close to periodic) tilings even if we allow some (sparse enough) tiling errors. This property was not known for any of the existing aperiodic tile sets.

  13. Rational points on elliptic curves

    CERN Document Server

    Silverman, Joseph H

    2015-01-01

    The theory of elliptic curves involves a pleasing blend of algebra, geometry, analysis, and number theory. This book stresses this interplay as it develops the basic theory, thereby providing an opportunity for advanced undergraduates to appreciate the unity of modern mathematics. At the same time, every effort has been made to use only methods and results commonly included in the undergraduate curriculum. This accessibility, the informal writing style, and a wealth of exercises make Rational Points on Elliptic Curves an ideal introduction for students at all levels who are interested in learning about Diophantine equations and arithmetic geometry. Most concretely, an elliptic curve is the set of zeroes of a cubic polynomial in two variables. If the polynomial has rational coefficients, then one can ask for a description of those zeroes whose coordinates are either integers or rational numbers. It is this number theoretic question that is the main subject of this book. Topics covered include the geometry and ...

  14. The Herschel Point Source Catalogue

    CERN Document Server

    Marton, Gábor; Altieri, Bruno; Calzoletti, Luca; Kiss, Csaba; Lim, Tanya; Lu, Nanyao; Paladini, Roberta; Papageorgiou, Andreas; Pearson, Chris; Rector, John; Shupe, David; Valtchanov, Ivan; Varga-Verebélyi, Erika; Xu, Kevin

    2015-01-01

    The Herschel Space Observatory was the fourth cornerstone mission in the European Space Agency (ESA) science programme with excellent broad band imaging capabilities in the sub-mm and far-infrared part of the spectrum. Although the spacecraft finished its observations in 2013, it left a large legacy dataset that is far from having been fully scrutinised and still has a large potential for new scientific discoveries. This is specifically true for the photometric observations of the PACS and SPIRE instruments. Some source catalogues have already been produced by individual observing programs, but there are many observations that risk to remain unexplored. To maximise the science return of the SPIRE and PACS data sets, we are in the process of building the Herschel Point Source Catalogue (HPSC) from all primary and parallel mode observations. Our homogeneous source extraction enables a systematic and unbiased comparison of sensitivity across the different Herschel fields that single programs will generally not b...

  15. Iterative approximation of fixed points

    CERN Document Server

    Berinde, Vasile

    2007-01-01

    The aim of this monograph is to give a unified introductory treatment of the most important iterative methods for constructing fixed points of nonlinear contractive type mappings. It summarizes the most significant contributions in the area by presenting, for each iterative method considered (Picard iteration, Krasnoselskij iteration, Mann iteration, Ishikawa iteration etc.), some of the most relevant, interesting, representative and actual convergence theorems. Applications to the solution of nonlinear operator equations as well as the appropriate error analysis of the main iterative methods, are also presented. Due to the explosive number of research papers on the topic (in the last 15 years only, more than one thousand articles related to the subject were published), it was felt that such a monograph was imperatively necessary. The volume is useful for authors, editors, and reviewers. It introduces concrete criteria for evaluating and judging the plethora of published papers.

  16. Vortex Laser at Exceptional Point

    CERN Document Server

    Wang, Xing-Yuan; Li, Ying; Li, Bo; Ma, Ren-Min

    2016-01-01

    The optical vortices carrying orbital angular momentum (OAM) are commonly generated by modulating the available conventional light beam. This article shows that a micro-laser operates at the exceptional point (EP) of the non-Hermitian quantum system can directly emit vortex laser with well-defined OAM at will. Two gratings (the refractive index modulation and along azimuthal direction and the grating protruding from the micro-ring cavity) modulate the eigenmode of a micro-ring cavity to be a vortex laser mode. The phase-matching condition ensures that we can tune the OAM of the vortex beam to be arbitrary orders by changing the grating protruding from the micro-ring cavity while the system is kept at EP. The results are obtained by analytical analysis and confirmed by 3D full wave simulations.

  17. Critical Point Symmetries in Nuclei

    CERN Document Server

    Bonatsos, D; Petrellis, D; Terziev, P A; Yigitoglu, I; Bonatsos, Dennis

    2006-01-01

    Critical Point Symmetries (CPS) appear in regions of the nuclear chart where a rapid change from one symmetry to another is observed. The first CPSs, introduced by F. Iachello, were E(5), which corresponds to the transition from vibrational [U(5)] to gamma-unstable [O(6)] behaviour, and X(5), which represents the change from vibrational [U(5)] to prolate axially deformed [SU(3)] shapes. These CPSs have been obtained as special solutions of the Bohr collective Hamiltonian. More recent special solutions of the same Hamiltonian, to be described here, include Z(5) and Z(4), which correspond to maximally triaxial shapes (the latter with ``frozen'' gamma=30 degrees), as well as X(3), which corresponds to prolate shapes with ``frozen'' gamma=0. CPSs have the advantage of providing predictions which are parameter free (up to overall scale factors) and compare well to experiment. However, their mathematical structure [with the exception of E(5)] needs to be clarified.

  18. Interpolating point spread function anisotropy

    CERN Document Server

    Gentile, M; Meylan, G

    2012-01-01

    Planned wide-field weak lensing surveys are expected to reduce the statistical errors on the shear field to unprecedented levels. In contrast, systematic errors like those induced by the convolution with the point spread function (PSF) will not benefit from that scaling effect and will require very accurate modeling and correction. While numerous methods have been devised to carry out the PSF correction itself, modeling of the PSF shape and its spatial variations across the instrument field of view has, so far, attracted much less attention. This step is nevertheless crucial because the PSF is only known at star positions while the correction has to be performed at any position on the sky. A reliable interpolation scheme is therefore mandatory and a popular approach has been to use low-order bivariate polynomials. In the present paper, we evaluate four other classical spatial interpolation methods based on splines (B-splines), inverse distance weighting (IDW), radial basis functions (RBF) and ordinary Kriging...

  19. Understanding of myofascial trigger points

    Institute of Scientific and Technical Information of China (English)

    Zhuang Xiaoqiang; Tan Shusheng; Huang Qiangmin

    2014-01-01

    Objective To investigate the current practice of myofascial pain syndrome (MPS) including current epidemiology,pathology,diagnosis and treatment.Data sources The data analyzed in this review were mainly from relevant articles without restriction on the publication date reported in PubMed,MedSci,Google scholar.The terms "myofasial trigger points" and "myofacial pain syndrome" were used for the literature search.Study selection Original articles with no limitation of research design and critical reviews containing data relevant to myofascial trigger points (MTrPs) and MPS were retrieved,reviewed,analyzed and summarized.Results Myofascial pain syndrome (MPS) is characterized by painful taut band,referred pain,and local response twitch with a prevalence of 85% to 95% of incidence.Several factors link to the etiology of MTrPs,such as the chronic injury and overload of muscles.Other factors,such as certain nutrient and hormone insufficiency,comorbidities,and muscle imbalance may also maintain the MTrP in an active status and induce recurrent pain.The current pathology is that an extra leakage acetylcholine at the neuromuscular junction induces persistent contracture knots,relative to some hypotheses of integration,muscle spindle discharges,spinal segment sensitization,ect.MTrPs can be diagnosed and localized based on a few subjective criteria.Several approaches,including both direct and supplementary treatments,can inactivate MTrPs.Direct treatments are categorized into invasive and conservative.Conclusion This review provides a clear understanding of MTrP pain and introduces the most useful treatment approaches in China.

  20. Professional SharePoint 2010 Development

    CERN Document Server

    Rizzo, Tom; Fried, Jeff

    2010-01-01

    Learn to leverage the features of the newest version of SharePoint, in this update to the bestseller. More than simply a portal, SharePoint is Microsoft's popular content management solution for building intranets and Web sites or hosting wikis and blogs. Offering broad coverage on all aspects of development for the SharePoint platform, this comprehensive book shows you exactly what SharePoint does, how to build solutions, and what features are accessible within SharePoint. Written by one of the most recognized names in SharePoint development, Professional SharePoint 2010 Development offers an

  1. 49 CFR 236.327 - Switch, movable-point frog or split-point derail.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Switch, movable-point frog or split-point derail..., AND APPLIANCES Interlocking Rules and Instructions § 236.327 Switch, movable-point frog or split-point derail. Switch, movable-point frog, or split-point derail equipped with lock rod shall be maintained...

  2. Cosmetology: Task Analyses. Competency-Based Education.

    Science.gov (United States)

    Henrico County Public Schools, Glen Allen, VA. Virginia Vocational Curriculum Center.

    These task analyses are designed to be used in combination with the "Trade and Industrial Education Service Area Resource" in order to implement competency-based education in the cosmetology program in Virginia. The task analysis document contains the task inventory, suggested task sequence lists, and content outlines for the secondary courses…

  3. Chemical Analyses of Silicon Aerogel Samples

    CERN Document Server

    van der Werf, I; De Leo, R; Marrone, S

    2008-01-01

    After five years of operating, two Aerogel counters: A1 and A2, taking data in Hall A at Jefferson Lab, suffered a loss of performance. In this note possible causes of degradation have been studied. In particular, various chemical and physical analyses have been carried out on several Aerogel tiles and on adhesive tape in order to reveal the presence of contaminants.

  4. A gamma model for {DNA} mixture analyses

    OpenAIRE

    Cowell, R. G.; Lauritzen, S L; Mortera, J.

    2007-01-01

    We present a new methodology for analysing forensic identification problems involving DNA mixture traces where several individuals may have contributed to the trace. The model used for identification and separation of DNA mixtures is based on a gamma distribution for peak area values. In this paper we illustrate the gamma model and apply it on several real examples from forensic casework.

  5. Micromechanical photothermal analyser of microfluidic samples

    DEFF Research Database (Denmark)

    2014-01-01

    The present invention relates to a micromechanical photothermal analyser of microfluidic samples comprising an oblong micro-channel extending longitudinally from a support element, the micro-channel is made from at least two materials with different thermal expansion coefficients, wherein the...

  6. Amino acid analyses of Apollo 14 samples.

    Science.gov (United States)

    Gehrke, C. W.; Zumwalt, R. W.; Kuo, K.; Aue, W. A.; Stalling, D. L.; Kvenvolden, K. A.; Ponnamperuma, C.

    1972-01-01

    Detection limits were between 300 pg and 1 ng for different amino acids, in an analysis by gas-liquid chromatography of water extracts from Apollo 14 lunar fines in which amino acids were converted to their N-trifluoro-acetyl-n-butyl esters. Initial analyses of water and HCl extracts of sample 14240 and 14298 samples showed no amino acids above background levels.

  7. Meta-analyses on viral hepatitis

    DEFF Research Database (Denmark)

    Gluud, Lise L; Gluud, Christian

    2009-01-01

    This article summarizes the meta-analyses of interventions for viral hepatitis A, B, and C. Some of the interventions assessed are described in small trials with unclear bias control. Other interventions are supported by large, high-quality trials. Although attempts have been made to adjust...

  8. Analyses of hydraulic performance of velocity caps

    DEFF Research Database (Denmark)

    Christensen, Erik Damgaard; Degn Eskesen, Mark Chr.; Buhrkall, Jeppe;

    2014-01-01

    The hydraulic performance of a velocity cap has been investigated. Velocity caps are often used in connection with offshore intakes. CFD (computational fluid dynamics) examined the flow through the cap openings and further down into the intake pipes. This was combined with dimension analyses...

  9. Comparing functional annotation analyses with Catmap

    Directory of Open Access Journals (Sweden)

    Krogh Morten

    2004-12-01

    Full Text Available Abstract Background Ranked gene lists from microarray experiments are usually analysed by assigning significance to predefined gene categories, e.g., based on functional annotations. Tools performing such analyses are often restricted to a category score based on a cutoff in the ranked list and a significance calculation based on random gene permutations as null hypothesis. Results We analysed three publicly available data sets, in each of which samples were divided in two classes and genes ranked according to their correlation to class labels. We developed a program, Catmap (available for download at http://bioinfo.thep.lu.se/Catmap, to compare different scores and null hypotheses in gene category analysis, using Gene Ontology annotations for category definition. When a cutoff-based score was used, results depended strongly on the choice of cutoff, introducing an arbitrariness in the analysis. Comparing results using random gene permutations and random sample permutations, respectively, we found that the assigned significance of a category depended strongly on the choice of null hypothesis. Compared to sample label permutations, gene permutations gave much smaller p-values for large categories with many coexpressed genes. Conclusions In gene category analyses of ranked gene lists, a cutoff independent score is preferable. The choice of null hypothesis is very important; random gene permutations does not work well as an approximation to sample label permutations.

  10. FAME: Software for analysing rock microstructures

    Science.gov (United States)

    Hammes, Daniel M.; Peternell, Mark

    2016-05-01

    Determination of rock microstructures leads to a better understanding of the formation and deformation of polycrystalline solids. Here, we present FAME (Fabric Analyser based Microstructure Evaluation), an easy-to-use MATLAB®-based software for processing datasets recorded by an automated fabric analyser microscope. FAME is provided as a MATLAB®-independent Windows® executable with an intuitive graphical user interface. Raw data from the fabric analyser microscope can be automatically loaded, filtered and cropped before analysis. Accurate and efficient rock microstructure analysis is based on an advanced user-controlled grain labelling algorithm. The preview and testing environments simplify the determination of appropriate analysis parameters. Various statistic and plotting tools allow a graphical visualisation of the results such as grain size, shape, c-axis orientation and misorientation. The FAME2elle algorithm exports fabric analyser data to an elle (modelling software)-supported format. FAME supports batch processing for multiple thin section analysis or large datasets that are generated for example during 2D in-situ deformation experiments. The use and versatility of FAME is demonstrated on quartz and deuterium ice samples.

  11. Uncertainty quantification approaches for advanced reactor analyses.

    Energy Technology Data Exchange (ETDEWEB)

    Briggs, L. L.; Nuclear Engineering Division

    2009-03-24

    The original approach to nuclear reactor design or safety analyses was to make very conservative modeling assumptions so as to ensure meeting the required safety margins. Traditional regulation, as established by the U. S. Nuclear Regulatory Commission required conservatisms which have subsequently been shown to be excessive. The commission has therefore moved away from excessively conservative evaluations and has determined best-estimate calculations to be an acceptable alternative to conservative models, provided the best-estimate results are accompanied by an uncertainty evaluation which can demonstrate that, when a set of analysis cases which statistically account for uncertainties of all types are generated, there is a 95% probability that at least 95% of the cases meet the safety margins. To date, nearly all published work addressing uncertainty evaluations of nuclear power plant calculations has focused on light water reactors and on large-break loss-of-coolant accident (LBLOCA) analyses. However, there is nothing in the uncertainty evaluation methodologies that is limited to a specific type of reactor or to specific types of plant scenarios. These same methodologies can be equally well applied to analyses for high-temperature gas-cooled reactors and to liquid metal reactors, and they can be applied to steady-state calculations, operational transients, or severe accident scenarios. This report reviews and compares both statistical and deterministic uncertainty evaluation approaches. Recommendations are given for selection of an uncertainty methodology and for considerations to be factored into the process of evaluating uncertainties for advanced reactor best-estimate analyses.

  12. What's missing from avian global diversification analyses?

    Science.gov (United States)

    Reddy, Sushma

    2014-08-01

    The accumulation of vast numbers of molecular phylogenetic studies has contributed to huge knowledge gains in the evolutionary history of birds. This permits subsequent analyses of avian diversity, such as how and why diversification varies across the globe and among taxonomic groups. However, available genetic data for these meta-analyses are unevenly distributed across different geographic regions and taxonomic groups. To comprehend the impact of this variation on the interpretation of global diversity patterns, I examined the availability of genetic data for possible biases in geographic and taxonomic sampling of birds. I identified three main disparities of sampling that are geographically associated with latitude (temperate, tropical), hemispheres (East, West), and range size. Tropical regions, which host the vast majority of species, are substantially less studied. Moreover, Eastern regions, such as the Old World Tropics and Australasia, stand out as being disproportionately undersampled, with up to half of communities not being represented in recent studies. In terms of taxonomic discrepancies, a majority of genetically undersampled clades are exclusively found in tropical regions. My analysis identifies several disparities in the key regions of interest of global diversity analyses. Differential sampling can have considerable impacts on these global comparisons and call into question recent interpretations of latitudinal or hemispheric differences of diversification rates. Moreover, this review pinpoints understudied regions whose biota are in critical need of modern systematic analyses.

  13. The Economic Cost of Homosexuality: Multilevel Analyses

    Science.gov (United States)

    Baumle, Amanda K.; Poston, Dudley, Jr.

    2011-01-01

    This article builds on earlier studies that have examined "the economic cost of homosexuality," by using data from the 2000 U.S. Census and by employing multilevel analyses. Our findings indicate that partnered gay men experience a 12.5 percent earnings penalty compared to married heterosexual men, and a statistically insignificant earnings…

  14. Comparison of veterinary import risk analyses studies

    NARCIS (Netherlands)

    Vos-de Jong, de C.J.; Conraths, F.J.; Adkin, A.; Jones, E.M.; Hallgren, G.S.; Paisley, L.G.

    2011-01-01

    Twenty-two veterinary import risk analyses (IRAs) were audited: a) for inclusion of the main elements of risk analysis; b) between different types of IRAs; c) between reviewers' scores. No significant differences were detected between different types of IRAs, although quantitative IRAs and IRAs publ

  15. L'analyse qualitative comme approche multiple

    Directory of Open Access Journals (Sweden)

    Roberto Cipriani

    2009-11-01

    Full Text Available L’exemple de l’enquête historique, visant à identifier les caractéristiques de la naissance et du développement d’une science et des lectures qu’elle donne des événements sociaux, est des plus originaux. Toute méthodologie historique non seulement débouche sur une pure et simple masse d’épisodes et d’événements, mais est également une narration et une élaboration critique de ces mêmes faits. Michael Postan écrit à juste titre que la complexité des données historiques est cependant de telle nature, et les différences et les similitudes tellement difficiles à cerner, que les efforts des historiens et des sociologues pour construire des comparaisons explicites se sont soldées, pour la plupart, par des tentatives grossières et naïves. La leçon des Annales a contribué en effet à construire l’idée d’une histoire qui puisse lire et expliquer ce qui est uniforme et ce qui est singulier. Rien de plus naturel que la réunion d’« êtres psychiques », à l’instar de l’assemblage des cellules en un organisme, en un « être psychique » nouveau et différent. Un tournant s’impose donc vers une expérimentation empirique plus ample et plus correcte, afin de disposer des instruments adéquats, capables de garantir à la méthodologie micro, qualitative et biographique, une fiabilité suffisante.Historical approach offers a relevant contribution in order to find the features of birth and development of a science which analyses social events. Historical methodology produces not only a lot of data but also a narrative, and an interpretation of facts. According to Michael Postan, history and sociology have made many efforts to compare data that are complex but similar and different at the same time. And the results seem to be naïf. Thanks to Les Annales suggestion it is possible to read and to explain what is uniform and what is singular. To put together “psychical beings”, like organic cells, in a new

  16. RBMK-LOCA-Analyses with the ATHLET-Code

    Energy Technology Data Exchange (ETDEWEB)

    Petry, A. [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH Kurfuerstendamm, Berlin (Germany); Domoradov, A.; Finjakin, A. [Research and Development Institute of Power Engineering, Moscow (Russian Federation)

    1995-09-01

    The scientific technical cooperation between Germany and Russia includes the area of adaptation of several German codes for the Russian-designed RBMK-reactor. One point of this cooperation is the adaptation of the Thermal-Hydraulic code ATHLET (Analyses of the Thermal-Hydraulics of LEaks and Transients), for RBMK-specific safety problems. This paper contains a short description of a RBMK-1000 reactor circuit. Furthermore, the main features of the thermal-hydraulic code ATHLET are presented. The main assumptions for the ATHLET-RBMK model are discussed. As an example for the application, the results of test calculations concerning a guillotine type rupture of a distribution group header are presented and discussed, and the general analysis conditions are described. A comparison with corresponding RELAP-calculations is given. This paper gives an overview on some problems posed and experience by application of Western best-estimate codes for RBMK-calculations.

  17. Monte Carlo uncertainty analyses for integral beryllium experiments

    CERN Document Server

    Fischer, U; Tsige-Tamirat, H

    2000-01-01

    The novel Monte Carlo technique for calculating point detector sensitivities has been applied to two representative beryllium transmission experiments with the objective to investigate the sensitivity of important responses such as the neutron multiplication and to assess the related uncertainties due to the underlying cross-section data uncertainties. As an important result, it has been revealed that the neutron multiplication power of beryllium can be predicted with good accuracy using state-of-the-art nuclear data evaluations. Severe discrepancies do exist for the spectral neutron flux distribution that would transmit into significant uncertainties of the calculated neutron spectra and of the nuclear blanket performance in blanket design calculations. With regard to this, it is suggested to re-analyse the secondary energy and angle distribution data of beryllium by means of Monte Carlo based sensitivity and uncertainty calculations. Related code development work is underway.

  18. Effects of acidosis, alkalosis, hyperthermia and hypothermia on haemostasis : results of point of care testing with the thromboelastography analyser

    NARCIS (Netherlands)

    Ramaker, Albert J. D. W. R.; Meyer, Peter; van der Meer, Jan; Struys, Michel M. R. F.; Lisman, Ton; van Oeveren, Wim; Hendriks, Herman G. D.

    2009-01-01

    In this study we assessed the effects of changes in pH, temperature, and their combination in whole blood on thromboelastographic variables. Blood was collected from six healthy volunteers. Thromboelastograph (TEG series 5000; Haemoscope Corporation, Illinois, USA) channels were set at temperatures

  19. Point processes statistics of stable isotopes: analysing water uptake patterns in a mixed stand of Aleppo pine and Holm oak

    OpenAIRE

    Carles Comas; Jorge del Castillo; Jordi Voltas; Juan Pedro Ferrio

    2015-01-01

    Aim of study: Understanding inter- and intra-specific competition for water is crucial in drought-prone environments. However, little is known about the spatial interdependencies for water uptake among individuals in mixed stands. The aim of this work was to compare water uptake patterns during a drought episode in two common Mediterranean tree species, Quercus ilex L. and Pinus halepensis Mill., using the isotope composition of xylem water (δ18O, δ2 H) as hydrological marker. ...

  20. Beginning SharePoint 2010 Administration Windows SharePoint Foundation 2010 and Microsoft SharePoint Server 2010

    CERN Document Server

    Husman, Göran

    2010-01-01

    Complete coverage on the latest advances in SharePoint 2010 administration. SharePoint 2010 comprises an abundance of new features, and this book shows you how to take advantage of all SharePoint 2010's many improvements. Written by a four-time SharePoint MVP, Beginning SharePoint 2010 Administration begins with a comparison of SharePoint 2010 compared to the previous version and then examines the differences between WSS 4.0 and MSS 2010. Packed with step-by-step instructions, tips and tricks, and real-world examples, this book dives into the basics of how to install, manage, and administrate

  1. Analysing Theoretical Frameworks of Moral Education through Lakatos's Philosophy of Science

    Science.gov (United States)

    Han, Hyemin

    2014-01-01

    The structure of studies of moral education is basically interdisciplinary; it includes moral philosophy, psychology, and educational research. This article systematically analyses the structure of studies of moral educational from the vantage points of philosophy of science. Among the various theoretical frameworks in the field of philosophy of…

  2. The Software Point of View

    CERN Multimedia

    Bentvelsen, Stan

    Physics was meant to be the topic of the LUND workshop, but it was software that dominated throughout the week. ATLAS' new software proves a tough nut to crack. Many presented physics analyses were repetitions of the Physics TDR, using (or trying to use) the new software. The main purpose was to demonstrate that results were invariant with new software. Hard to prove since the 'new software' is not yet completed. Nevertheless the so far existing sofware is massively experimented with throughout the entire ATLAS community. So what does this "new software" really mean? The answer depends strongly on the person who deals with this question. The scope varies between "migrating from Fortran77 to C++" and "learn Object Oriented approach" to "implementing services and algorithms in Athena" or "feeding detector description in FADS". Clearly the new software primarily involves migrating from the old Fortran code to C++ with its object oriententation paradigm. Occasionaly there was a hint that this migration is not c...

  3. Do Danish food companies analyse their competitors?

    DEFF Research Database (Denmark)

    Grunert, Klaus G.; Nissen, Lars; Wildenhoff, Lars

    1993-01-01

    Executive summary: 1. Modern marketing knowledge points out that competitor analysis is equally important as customer analysis for the attainment of sustainable competitive advantage, given the ways in which market environments have changed in the seventies and eighties. 2. A study based...

  4. Decision Point 1 Topical Report

    Energy Technology Data Exchange (ETDEWEB)

    Yablonsky, Al; Barsoumian, Shant; Legere, David

    2013-05-01

    This Topical Report addresses accomplishments achieved during Phase 2a of the SkyMine® Carbon Mineralization Pilot Project. The primary objectives of this project are to design, construct, and operate a system to capture CO2 from a slipstream of flue gas from a commercial coal-fired cement kiln, convert that CO2 to products having commercial value (i.e., beneficial use), show the economic viability of the CO2 capture and conversion process, and thereby advance the technology to the point of readiness for commercial scale demonstration and proliferation. The overall process is carbon negative, resulting in mineralization of CO2 that would otherwise be released into the atmosphere. The project will also substantiate market opportunities for the technology by sales of chemicals into existing markets, and identify opportunities to improve technology performance and reduce costs at the commercial scale. The project is being conducted in two phases. The primary objectives of Phase 1 were to elaborate proven SkyMine® process chemistry to commercial pilot-scale operation and complete the preliminary design for the pilot plant to be built and operated in Phase 2, complete a NEPA evaluation, and develop a comprehensive carbon life cycle analysis. The objective of the current Phase (2a) is to complete the detailed design of the pilot plant to be built in Phase 2b.

  5. Inflection point inflation within supersymmetry

    Energy Technology Data Exchange (ETDEWEB)

    Enqvist, Kari [Physics Department and Helsinki Institute of Physics, FI-00014 University of Helsinki (Finland); Mazumdar, Anupam; Stephens, Philip, E-mail: kari.enqvist@helsinki.fi, E-mail: a.mazumdar@lancaster.ac.uk, E-mail: p.stephens@lancaster.ac.uk [Physics Department, Lancaster University, Lancaster, LA1 4YB (United Kingdom)

    2010-06-01

    We propose to address the fine tuning problem of inflection point inflation by the addition of extra vacuum energy that is present during inflation but disappears afterwards. We show that in such a case, the required amount of fine tuning is greatly reduced. We suggest that the extra vacuum energy can be associated with an earlier phase transition and provide a simple model, based on extending the SM gauge group to SU(3){sub C} × SU(2){sub L} × U(1){sub Y} × U(1){sub B−L}, where the Higgs field of U(1){sub B−L} is in a false vacuum during inflation. In this case, there is virtually no fine tuning of the soft SUSY breaking parameters of the flat direction which serves as the inflaton. However, the absence of radiative corrections which would spoil the flatness of the inflaton potential requires that the U(1){sub B−L} gauge coupling should be small with g{sub B−L} ≤ 10{sup −4}.

  6. Comparison of Dose When Prescribed to Point A and Point H for Brachytherapy in Cervical Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Gang, Ji Hyeong; Gim, Il Hwan; Hwang, Seon Boong; Kim, Woong; Im, Hyeong Seo; Gang, Jin Mook; Gim, Gi Hwan; Lee, Ah Ram [Dept. of Radiation Oncology, Korea Institute of Radiological and Medical Sciences, Seou (Korea, Republic of)

    2012-09-15

    The purpose of this study is to compare plans prescribed to point A with these prescribed to point H recommended by ABS (American Brachytherapy Society) in high dose rate intracavitary brachytherapy for cervical carcinoma. This study selected 103 patients who received HDR (High Dose Rate) brachytherapy using tandem and ovoids from March 2010 to January 2012. Point A, bladder point, and rectal point conform with Manchester System. Point H conforms with ABS recommendation. Also Sigmoid colon point, and vagina point were established arbitrarily. We examined distance between point A and point H. The percent dose at point A was calculated when 100% dose was prescribed to point H. Additionally, the percent dose at each reference points when dose is prescribed to point H and point A were calculated. The relative dose at point A was lower when point H was located inferior to point A. The relative doses at bladder, rectal, sigmoid colon, and vagina points were higher when point H was located superior to point A, and lower when point H was located inferior to point A. This study found out that as point H got located much superior to point A, the absorbed dose of surrounding normal organs became higher, and as point H got located much inferior to point A, the absorbed dose of surrounding normal organs became lower. This differences dose not seem to affect the treatment. However, we suggest this new point is worth being considered for the treatment of HDR if dose distribution and absorbed dose at normal organs have large differences between prescribed to point A and H.

  7. Sensitivity of surface meteorological analyses to observation networks

    Science.gov (United States)

    Tyndall, Daniel Paul

    A computationally efficient variational analysis system for two-dimensional meteorological fields is developed and described. This analysis approach is most efficient when the number of analysis grid points is much larger than the number of available observations, such as for large domain mesoscale analyses. The analysis system is developed using MATLAB software and can take advantage of multiple processors or processor cores. A version of the analysis system has been exported as a platform independent application (i.e., can be run on Windows, Linux, or Macintosh OS X desktop computers without a MATLAB license) with input/output operations handled by commonly available internet software combined with data archives at the University of Utah. The impact of observation networks on the meteorological analyses is assessed by utilizing a percentile ranking of individual observation sensitivity and impact, which is computed by using the adjoint of the variational surface assimilation system. This methodology is demonstrated using a case study of the analysis from 1400 UTC 27 October 2010 over the entire contiguous United States domain. The sensitivity of this approach to the dependence of the background error covariance on observation density is examined. Observation sensitivity and impact provide insight on the influence of observations from heterogeneous observing networks as well as serve as objective metrics for quality control procedures that may help to identify stations with significant siting, reporting, or representativeness issues.

  8. Local analyses of Planck maps with Minkowski Functionals

    CERN Document Server

    Novaes, C P; Marques, G A; Ferreira, I S

    2016-01-01

    Minkowski Functionals (MF) are excellent tools to investigate the statistical properties of the cosmic background radiation (CMB) maps. Between their notorious advantages is the possibility to use them efficiently in patches of the CMB sphere, which allow studies in masked skies, inclusive analyses of small sky regions. Then, possible deviations from Gaussianity are investigated by comparison with MF obtained from a set of Gaussian isotropic simulated CMB maps to which are applied the same cut-sky masks. These analyses are sensitive enough to detect contaminations of small intensity like primary and secondary CMB anisotropies. Our methodology uses the MF, widely employed to study non-Gaussianities in CMB data, and asserts Gaussian deviations only when all of them points out an exceptional $\\chi^2$ value, at more than $2.2 \\sigma$ confidence level, in a given sky patch. Following this rigorous procedure, we find 13 regions in the foreground-cleaned Planck maps that evince such high levels of non-Gaussian devia...

  9. Complementary microstructural and chemical analyses of Sepia officinalis endoskeleton

    Energy Technology Data Exchange (ETDEWEB)

    Florek, Marek, E-mail: mflorek@kul.lublin.pl [Department of Chemistry, John Paul II Catholic University of Lublin, al. Krasnicka 102, 20-718 Lublin (Poland); Fornal, Emilia [Department of Chemistry, John Paul II Catholic University of Lublin, al. Krasnicka 102, 20-718 Lublin (Poland); Gomez-Romero, Pedro [Institut de Ciencia de Materials de Barcelona (CSIC), Campus UAB, E-08193 Bellaterra, Barcelona (Spain); Zieba, Emil [Department of Chemistry, John Paul II Catholic University of Lublin, al. Krasnicka 102, 20-718 Lublin (Poland); Paszkowicz, Wojciech [Institute of Physics, Polish Academy of Sciences, Al. Lotnikow 32/46, 02-668 Warsaw (Poland); Lekki, Janusz [Niewodniczanski Institute of Nuclear Physics, Polish Academy of Sciences, ul. Radzikowskiego 152, 31-342 Krakow (Poland); Nowak, Jakub; Kuczumow, Andrzej [Department of Chemistry, John Paul II Catholic University of Lublin, al. Krasnicka 102, 20-718 Lublin (Poland)

    2009-05-05

    Cuttlebone exhibiting high compressive strength is a very interesting material from the biomimetic materials' technology point of view. Its microstructure and chemical composition were characterized by complementary analytical techniques. Structural features of the skeleton were revealed by SEM, micro-Raman, FT-IR and XRD measurements. XRD analyses showed that the only mineral phase present in the samples is aragonite. 2D-maps obtained from micro-Raman analyses for peaks attributed to aragonite (1100 cm{sup -1}) and chitin (1660 cm{sup -1}) revealed that the septa are richer in chitin and pillars in aragonite. 2D-distributions of elements detected by a electron microprobe showed that Ca-rich locations are poor in Mg, Na, and Br. Ca is mainly present at those locations where aragonite prevails. Bromine, sodium and magnesium are most likely located in the organic matrix. The average content of the elements, as determined by ICP-OES, was: Na - 1.0%, Mg - 0.133%, K - 0.26%, Fe - 0.03% and Sr - 0.28%. Using the elemental CHN analysis the following amounts of nitrogen, carbon and hydrogen were detected: 1.42%, 15.36% and 0.68%, respectively. The elemental analysis together with TGA measurements allowed evaluating the approximate concentration of organic matter in the cuttlebone at the level of 10%.

  10. Quantifying global dust devil occurrence from meteorological analyses

    Science.gov (United States)

    Jemmett-Smith, Bradley C; Marsham, John H; Knippertz, Peter; Gilkeson, Carl A

    2015-01-01

    Dust devils and nonrotating dusty plumes are effective uplift mechanisms for fine particles, but their contribution to the global dust budget is uncertain. By applying known bulk thermodynamic criteria to European Centre for Medium-Range Weather Forecasts (ECMWF) operational analyses, we provide the first global hourly climatology of potential dust devil and dusty plume (PDDP) occurrence. In agreement with observations, activity is highest from late morning into the afternoon. Combining PDDP frequencies with dust source maps and typical emission values gives the best estimate of global contributions of 3.4% (uncertainty 0.9–31%), 1 order of magnitude lower than the only estimate previously published. Total global hours of dust uplift by dry convection are ∼0.002% of the dust-lifting winds resolved by ECMWF, consistent with dry convection making a small contribution to global uplift. Reducing uncertainty requires better knowledge of factors controlling PDDP occurrence, source regions, and dust fluxes induced by dry convection. Key Points Global potential dust devil occurrence quantified from meteorological analyses Climatology shows realistic diurnal cycle and geographical distribution Best estimate of global contribution of 3.4% is 10 times smaller than the previous estimate PMID:26681815

  11. Optimal control of decoupling point with deteriorating items

    Directory of Open Access Journals (Sweden)

    Kuan Yang

    2014-10-01

    Full Text Available Purpose: The aim of this paper is to develop a dynamic model to simultaneously determine the optimal position of the decoupling point and the optimal path of the production rate as well as the inventory level in a supply chain. With the objective to minimize the total cost of the deviation from the target setting, the closed forms of the optimal solution are derived over a finite planning horizon with deterioration rate under time-varying demand rate.Design/methodology/approach: The Pontryagin's Maximum Principle is employed to explore the optimal position of decoupling point and the optimal production and inventory rate for the proposed dynamic models. The performances of parameters are illustrated through analytical and numerical approaches.Findings: The results denote that the optimal production rate and inventory level are closely related to the target setting which are highly dependent on production policy; meanwhile the optimal decoupling point is exist and unique with the fluctuating of deteriorating rate and product life cycle. The further analyses through both mathematic and numerical approaches indicate that the shorten of product life cycle shifts the optimal decoupling point forward to the end customer meanwhile a backward shifting appears when the deterioration rate increase.Research limitations/implications: There is no shortage allowed and the replacement policy is not taken into account.Practical implications: Solutions derived from this study of the optimal production-inventory plan and decoupling point are instructive for operation decision making. The obtained knowledge about the performance of different parameters is critical to deteriorating supply chains management.Originality/value: Many previous models of the production-inventory problem are only focused on the cost. The paper introduces the decoupling point control into the production and inventory problem such that a critical element-customer demand, can be taken into

  12. Identifying, analysing and solving problems in practice.

    Science.gov (United States)

    Hewitt-Taylor, Jaqui

    When a problem is identified in practice, it is important to clarify exactly what it is and establish the cause before seeking a solution. This solution-seeking process should include input from those directly involved in the problematic situation, to enable individuals to contribute their perspective, appreciate why any change in practice is necessary and what will be achieved by the change. This article describes some approaches to identifying and analysing problems in practice so that effective solutions can be devised. It includes a case study and examples of how the Five Whys analysis, fishbone diagram, problem tree analysis, and Seven-S Model can be used to analyse a problem. PMID:22848969

  13. Analyses of cavitation instabilities in ductile metals

    DEFF Research Database (Denmark)

    Tvergaard, Viggo

    2007-01-01

    , and also tests for a thin ductile metal layer bonding two ceramic blocks have indicated rapid void growth. Analyses for these material configurations are discussed here. When the void radius is very small, a nonlocal plasticity model is needed to account for observed size-effects, and recent analyses...... analyzed for a material containing a periodic distribution of spherical voids with two different void sizes, where the stress fields around larger voids may accelerate the growth of smaller voids. Another approach has been an analysis of a unit cell model in which a central cavity is discretely represented......, while the surrounding voids are represented by a porous ductile material model in terms of a field quantity that specifies the variation of the void volume fraction in the surrounding metal....

  14. Reliability of chemical analyses of water samples

    Energy Technology Data Exchange (ETDEWEB)

    Beardon, R.

    1989-11-01

    Ground-water quality investigations require reliable chemical analyses of water samples. Unfortunately, laboratory analytical results are often unreliable. The Uranium Mill Tailings Remedial Action (UMTRA) Project`s solution to this problem was to establish a two phase quality assurance program for the analysis of water samples. In the first phase, eight laboratories analyzed three solutions of known composition. The analytical accuracy of each laboratory was ranked and three laboratories were awarded contracts. The second phase consists of on-going monitoring of the reliability of the selected laboratories. The following conclusions are based on two years experience with the UMTRA Project`s Quality Assurance Program. The reliability of laboratory analyses should not be taken for granted. Analytical reliability may be independent of the prices charged by laboratories. Quality assurance programs benefit both the customer and the laboratory.

  15. Professional SharePoint 2010 Administration

    CERN Document Server

    Klindt, Todd; Caravajal, Steve

    2010-01-01

    Thorough coverage of the improvements and changes to SharePoint 2010. SharePoint 2010 boasts a variety of incredible new features that will challenge even the most experienced administrator who is upgrading from SharePoint 2007. Written by a team of SharePoint experts, this book places a takes aim at showing you how to make these new features work right for you. Offering an in-depth look at SharePoint 2010, the authors focus on how SharePoint functionality has changed from its earliest version to its newest, and they provide you with detailed coverage of all the new features and capabilities.:

  16. Professional SharePoint 2013 administration

    CERN Document Server

    Young, Shane; Klindt, Todd

    2013-01-01

    SharePoint admin author gurus return to prepare you for working with the new features of SharePoint 2013! The new iteration of SharePoint boasts exciting new features. However, any new version also comes with its fair share of challenges and that's where this book comes in. The team of SharePoint admin gurus returns to presents a fully updated resource that prepares you for making all the new SharePoint 2013 features work right. They cover all of the administration components of SharePoint 2013 in detail, and present a clear understanding of how they affect the role of the adminis

  17. SharePoint 2010 Field Guide

    CERN Document Server

    Mann, Steven; Gazmuri, Pablo; Caravajal, Steve; Wheeler, Christina

    2012-01-01

    Hands-on solutions for common SharePoint 2010 challenges Aimed at the more than 100 million licensed SharePoint 2010 users, this indispensable field guide addresses an abundance of common SharePoint 2010 problems and offers proven solutions. A team of authors encourages you to customize SharePoint beyond the out-of-the-box functionality so that you can build more complex solutions to these challenges. You?ll discover intricate details and specific full-scale solutions that you can then implement to your own SharePoint 2010 solutions.Tackles a variety of SharePoint 2010 problems ranging from si

  18. SharePoint 2010 For Dummies

    CERN Document Server

    Williams, Vanessa L

    2012-01-01

    Here's the bestselling guide on SharePoint 2010, updated to cover Office 365 SharePoint Portal Server is an essential part of the enterprise infrastructure for many businesses. The Office 365 version includes significantly enhanced cloud capabilities. This second edition of the bestselling guide to SharePoint covers getting a SharePoint site up and running, branded, populated with content, and more. It explains ongoing site management and offers plenty of advice for administrators who want to leverage SharePoint and Office 365 in various ways.Many businesses today rely on SharePoint Portal Ser

  19. Professional SharePoint 2010 Development

    CERN Document Server

    Rizzo, Tom; Fried, Jeff; Swider, Paul J; Hillier, Scot; Schaefer, Kenneth

    2012-01-01

    Updated guidance on how to take advantage of the newest features of SharePoint programmability More than simply a portal, SharePoint is Microsoft's popular content management solution for building intranets and websites or hosting wikis and blogs. Offering broad coverage on all aspects of development for the SharePoint platform, this comprehensive book shows you exactly what SharePoint does, how to build solutions, and what features are accessible within SharePoint. Written by a team of SharePoint experts, this new edition offers an extensive selection of field-tested best practices that shows

  20. Improving Climate Communication through Comprehensive Linguistic Analyses Using Computational Tools

    Science.gov (United States)

    Gann, T. M.; Matlock, T.

    2014-12-01

    An important lesson on climate communication research is that there is no single way to reach out and inform the public. Different groups conceptualize climate issues in different ways and different groups have different values and assumptions. This variability makes it extremely difficult to effectively and objectively communicate climate information. One of the main challenges is the following: How do we acquire a better understanding of how values and assumptions vary across groups, including political groups? A necessary starting point is to pay close attention to the linguistic content of messages used across current popular media sources. Careful analyses of that information—including how it is realized in language for conservative and progressive media—may ultimately help climate scientists, government agency officials, journalists and others develop more effective messages. Past research has looked at partisan media coverage of climate change, but little attention has been given to the fine-grained linguistic content of such media. And when researchers have done detailed linguistic analyses, they have relied primarily on hand-coding, an approach that is costly, labor intensive, and time-consuming. Our project, building on recent work on partisan news media (Gann & Matlock, 2014; under review) uses high dimensional semantic analyses and other methods of automated classification techniques from the field of natural language processing to quantify how climate issues are characterized in media sources that differ according to political orientation. In addition to discussing varied linguistic patterns, we share new methods for improving climate communication for varied stakeholders, and for developing better assessments of their effectiveness.

  1. Local analyses of Planck maps with Minkowski functionals

    Science.gov (United States)

    Novaes, C. P.; Bernui, A.; Marques, G. A.; Ferreira, I. S.

    2016-09-01

    Minkowski functionals (MF) are excellent tools to investigate the statistical properties of the cosmic background radiation (CMB) maps. Between their notorious advantages is the possibility to use them efficiently in patches of the CMB sphere, which allow studies in masked skies, inclusive analyses of small sky regions. Then, possible deviations from Gaussianity are investigated by comparison with MF obtained from a set of Gaussian isotropic simulated CMB maps to which are applied the same cut-sky masks. These analyses are sensitive enough to detect contaminations of small intensity like primary and secondary CMB anisotropies. Our methodology uses the MF, widely employed to study non-Gaussianities in CMB data, and asserts Gaussian deviations only when all of them points out an exceptional χ2 value, at more than 2.2σ confidence level, in a given sky patch. Following this rigorous procedure, we find 13 regions in the foreground-cleaned Planck maps that evince such high levels of non-Gaussian deviations. According to our results, these non-Gaussian contributions show signatures that can be associated to the presence of hot or cold spots in such regions. Moreover, some of these non-Gaussian deviations signals suggest the presence of foreground residuals in those regions located near the Galactic plane. Additionally, we confirm that most of the regions revealed in our analyses, but not all, have been recently reported in studies done by the Planck collaboration. Furthermore, we also investigate whether these non-Gaussian deviations can be possibly sourced by systematics, like inhomogeneous noise and beam effect in the released Planck data, or perhaps due to residual Galactic foregrounds.

  2. Mikromechanische Analyse der Wirkungsmechanismen elektrischer Dehnungsmessstreifen

    OpenAIRE

    Stockmann, Martin

    2000-01-01

    Die elektrische Dehnungsmesstechnik auf der Grundlage separater Dehnungsmessstreifen (DMS) stellt heute eine der wesentlichsten Methoden zur experimentellen Beanspruchungs- analyse dar. Präzise Messungen außerhalb der Kalibrierbedingungen, insbesondere bei großen Deformationen oder hohen Querdehnungsanteilen, erfordern die Berücksichtigung nicht- linearer Zusammenhänge zwischen den zu bestimmenden Komponenten der Bauteildehnung und der Widerstandsänderung des Messgitters. ...

  3. El Cours d’Analyse de Cauchy

    OpenAIRE

    Pérez, Javier; Aizpuru, Antonio

    1999-01-01

    En este artículo presentamos un estudio contextualizado de Cours d’Analyse de Cauchy, analizando su significado e importancia. Presentamos especial atención al grado de elaboración teórica de límites, continuidad, series, números reales funciones y series completas, relacionando las aportaciones de Cauchi del nivel conceptual anterior a esta ahora.

  4. Mass spectrometer for the analyses of gases

    International Nuclear Information System (INIS)

    A 6-in-radius, 600 magnetic-sector mass spectrometer (designated as the MS-200) has been constructed for the quantitative and qualitative analyses of fixed gases and volatile organics in the concentration range from 1 ppM (by volume) to 100%. A partial pressure of 1 x 10-6 torr in the inlet expansion volume is required to achieve a useful signal at an electron-multiplier gain of 10,000

  5. Ethics of cost analyses in medical education

    OpenAIRE

    Walsh, Kieran

    2013-01-01

    Cost analyses in medical education are rarely straightforward, and rarely lead to clear-cut conclusions. Occasionally they do lead to clear conclusions but even when that happens, some stakeholders will ask difficult but valid questions about what to do following cost analyses–specifically about distributive justice in the allocation of resources. At present there are few or no debates about these issues and rationing decisions that are taken in medical education are largely made subconscious...

  6. En Billig GPS Data Analyse Platform

    DEFF Research Database (Denmark)

    Andersen, Ove; Christiansen, Nick; Larsen, Niels T.;

    2011-01-01

    Denne artikel præsenterer en komplet software platform til analyse af GPS data. Platformen er bygget udelukkende vha. open-source komponenter. De enkelte komponenter i platformen beskrives i detaljer. Fordele og ulemper ved at bruge open-source diskuteres herunder hvilke IT politiske tiltage, der...... organisationer med et digitalt vejkort og GPS data begynde at lave trafikanalyser på disse data. Det er et krav, at der er passende IT kompetencer tilstede i organisationen....

  7. Delvis drenert analyse av innvendig avstivet utgraving

    OpenAIRE

    Myhrvold, Michael F

    2013-01-01

    Denne masteroppgaven omhandler analyser av de delvis drenerte effektene som kan oppstå ved innvendig, avstivede utgravinger. Formålet med masteroppgaven er å gjennomføre en numerisk studie av prosessen som styrer den tidsavhengige utviklingen ved avstivede utgravinger i lavpermeable jordtyper. Det gir muligheten til å vurdere de delvis drenerte effektene og innflytelsen disse utgjør ved denne typen utgravinger. Ettersom jordens oppførsel ved små tø...

  8. Crossing point temperature of coal

    Institute of Scientific and Technical Information of China (English)

    Qi Xuyao; Deming Wang; James A. Milke; Xiaoxing Zhong

    2011-01-01

    A further understanding of the self-heating of coal was obtained by investigating the crossing point temperature (CPT) of different ranks of coal. The tests were carried out using a self-designed experimental system for coal self-heating. 50 g (±0.01 g) of coal particles ranging from 0.18 mm to 0.38 mm in size were put into a pure copper reaction vessel attached to the center of a temperature programmed enclosure. The temperature program increased the temperature at a rate of 0.8 ℃/min. Dry air was permitted to flow into the coal reaction vessel at different rates. The surrounding temperature and the coal temperature were monitored by a temperature logger. The results indicate that CPT is affected by coal rank, moisture, sulfur,and the experimental conditions. Higher ranked coals show higher CPT values. A high moisture content causes a delay phenomenon during the self-heating of the coal. Drying at 40 ℃ decreases the effects of moisture. The reactivity of sulfur components in the coal is low under dry and low-temperature conditions.These components form a film that covers the coal surface and slightly inhibits the self-heating of the coal.The flow rate of dry air, and the heating rate of the surroundings, also affect the self-heating of the coal. The most appropriate experimental conditions for coal samples of a given weight and particle size were determined through contrastive analysis. Based on this analysis we propose that CPTs be determined under the same, or nearly the same conditions, for evaluation of the spontaneous combustion of coal.

  9. Collaborative interaction points in post-discharge stroke care

    Directory of Open Access Journals (Sweden)

    Nadia Davoody

    2014-11-01

    Full Text Available Introduction: Lack of appropriate electronic tools for supporting patient involvement and collaboration with care professionals is a problem in health care. Methods: Care and rehabilitation processes of post-discharge stroke patients were analysed using the concept of interaction points where patients, next-of-kin and care professionals interact and exchange information. Thirteen interviews with care professionals and five non-participatory observations were performed. Data were analysed using content analysis and modelling of interaction points in the patient journey. Results: Patient participation and interaction patterns vary; patients requiring home care have a passive role and next-of-kin or nurses become advocates by coordinating care on behalf of the patient, whereas patients who are able to visit primary care coordinate their own care by initiating interactions. Important categories of participation include the following: participation in care planning, in monitoring risk factors and in rehabilitation planning. Conclusions: Designing a supportive electronic tool requires understanding the interactions and patients’ activity levels at each interaction point. A tool for patients with higher activity level should support them to coordinate their own care, whereas for a less-active patient group, the tool could focus on supporting next-of-kin and care professionals in motivating, guiding and including passive patients in their care and rehabilitation processes.

  10. ANALYSING SPACE: ADAPTING AND EXTENDING MULTIMODAL SEMIOTICS

    Directory of Open Access Journals (Sweden)

    Louise J. Ravelli

    2015-07-01

    Full Text Available In the field of multimodal discourse analysis, one of the most exciting sites of application is that of 3D space: examining aspects of built environment for its meaningmaking potential. For the built environment – homes, offices, public buildings, parks, etc. – does indeed make meaning. These are spaces which speak – often their meanings are so familiar, we no longer hear what they say; sometimes, new and unusual sites draw attention to their meanings, and they are hotly contested. This chapter will suggest ways of analyzing 3D texts, based on the framework of Kress and van Leeuwen (2006. This framework, developed primarily for the analysis of 2D images, has been successfully extended to a range of other multimodal texts. Extension to the built environment includes Pang (2004, O’Toole (1994, Ravelli (2006, Safeyton (2004, Stenglin (2004 and White (1994, whose studies will inform the analyses presented here. This article will identify some of the key theoretical principles which underline this approach, including the notions of text, context and metafunction, and will describe some of the main areas of analysis for 3D texts. Also, ways of bringing the analyses together will be considered. The analyses will be demonstrated in relation to the Scientia building at the University of New South Wales, Australia.

  11. A sequential point process model and Bayesian inference for spatial point patterns with linear structures

    DEFF Research Database (Denmark)

    Møller, Jesper; Rasmussen, Jakob Gulddahl

    We introduce a flexible spatial point process model for spatial point patterns exhibiting linear structures, without incorporating a latent line process. The model is given by an underlying sequential point process model, i.e. each new point is generated given the previous points. Under this model...... previous points is such that the dependent cluster point is likely to occur closely to a previous cluster point. We demonstrate the flexibility of the model for producing point patterns with linear structures, and propose to use the model as the likelihood in a Bayesian setting when analyzing a spatial...

  12. Testing Local Independence between Two Point Processes

    DEFF Research Database (Denmark)

    Allard, Denis; Brix, Anders; Chadæuf, Joël

    2001-01-01

    Independence test, Inhomogeneous point processes, Local test, Monte Carlo, Nonstationary, Rotations, Spatial pattern, Tiger bush......Independence test, Inhomogeneous point processes, Local test, Monte Carlo, Nonstationary, Rotations, Spatial pattern, Tiger bush...

  13. Tallahatchie NWR - Landbird Point Counts in 2009

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Avian point counts were done in selected areas of mature forest on Tallahatchie Refuge in 2009. Report contains summary of avain point counts done in mature...

  14. Geometric Computations on Indecisive and Uncertain Points

    CERN Document Server

    Jorgensen, Allan; Phillips, Jeff M

    2012-01-01

    We study computing geometric problems on uncertain points. An uncertain point is a point that does not have a fixed location, but rather is described by a probability distribution. When these probability distributions are restricted to a finite number of locations, the points are called indecisive points. In particular, we focus on geometric shape-fitting problems and on building compact distributions to describe how the solutions to these problems vary with respect to the uncertainty in the points. Our main results are: (1) a simple and efficient randomized approximation algorithm for calculating the distribution of any statistic on uncertain data sets; (2) a polynomial, deterministic and exact algorithm for computing the distribution of answers for any LP-type problem on an indecisive point set; and (3) the development of shape inclusion probability (SIP) functions which captures the ambient distribution of shapes fit to uncertain or indecisive point sets and are admissible to the two algorithmic constructi...

  15. State Wildlife Management Area Public Facilities - points

    Data.gov (United States)

    Minnesota Department of Natural Resources — This point theme contains facilities and features for WMAs that are best represented as points. WMAs are part of the Minnesota state recreation system created to...

  16. 76 FR 38020 - Safety Zone; Bay Point Fireworks, Bay Point Marina; Marblehead, OH

    Science.gov (United States)

    2011-06-29

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Bay Point Fireworks, Bay Point Marina... transit or anchor in a portion of the Lake Erie, Bay Point Marina; Marblehead, OH between 10 p.m. and 10... Zone; Bay Point Fireworks, Bay Point Marina; Marblehead, OH. (a) Location. The following area is...

  17. A sequential point process model and Bayesian inference for spatial point patterns with linear structures

    DEFF Research Database (Denmark)

    Møller, Jesper; Rasmussen, Jakob Gulddahl

    We introduce a flexible spatial point process model for spatial point patterns exhibiting linear structures, without incorporating a latent line process. The model is given by an underlying sequential point process model, i.e. each new point is generated given the previous points. Under this mode...

  18. The Convex Coordinates of the Symmedian Point

    Science.gov (United States)

    Boyd, J. N.; Raychowdhury, P. N.

    2006-01-01

    In this note, we recall the convex (or barycentric) coordinates of the points of a closed triangular region. We relate the convex and trilinear coordinates of the interior points of the triangular region. We use the relationship between convex and trilinear coordinates to calculate the convex coordinates of the symmedian point of the triangular…

  19. Hardware Accelerated Point Rendering of Isosurfaces

    DEFF Research Database (Denmark)

    Bærentzen, Jakob Andreas; Christensen, Niels Jørgen

    2003-01-01

    and that the advantage of rendering points as opposed to triangles increases with the size and complexity of the volumes. To gauge the visual quality of future hardware accelerated point rendering schemes, we have implemented a software based point rendering method and compare the quality to both MC and our OpenGL based...

  20. Residual analysis for spatial point processes

    DEFF Research Database (Denmark)

    Baddeley, A.; Turner, R.; Møller, Jesper;

    We define residuals for point process models fitted to spatial point pattern data, and propose diagnostic plots based on these residuals. The techniques apply to any Gibbs point process model, which may exhibit spatial heterogeneity, interpoint interaction and dependence on spatial covariates. Ou...

  1. Inhomogeneous Markov point processes by transformation

    DEFF Research Database (Denmark)

    Jensen, Eva B. Vedel; Nielsen, Linda Stougaard

    2000-01-01

    We construct parametrized models for point processes, allowing for both inhomogeneity and interaction. The inhomogeneity is obtained by applying parametrized transformations to homogeneous Markov point processes. An interesting model class, which can be constructed by this transformation approach......, is that of exponential inhomogeneous Markov point processes. Statistical inference For such processes is discussed in some detail....

  2. Department of Energy's team's analyses of Soviet designed VVERs

    Energy Technology Data Exchange (ETDEWEB)

    1989-09-01

    This document provides Appendices A thru K of this report. The topics discussed respectively are: radiation induced embrittlement and annealing of reactor pressure vessel steels; loss of coolant accident blowdown analyses; LOCA blowdown response analyses; non-seismic structural response analyses; seismic analyses; S'' seal integrity; reactor transient analyses; fire protection; aircraft impacts; and boric acid induced corrosion. (FI).

  3. Evaluation of Model Operational Analyses during DYNAMO

    Science.gov (United States)

    Ciesielski, Paul; Johnson, Richard

    2013-04-01

    A primary component of the observing system in the DYNAMO-CINDY2011-AMIE field campaign was an atmospheric sounding network comprised of two sounding quadrilaterals, one north and one south of the equator over the central Indian Ocean. During the experiment a major effort was undertaken to ensure the real-time transmission of these data onto the GTS (Global Telecommunication System) for dissemination to the operational centers (ECMWF, NCEP, JMA, etc.). Preliminary estimates indicate that ~95% of the soundings from the enhanced sounding network were successfully transmitted and potentially used in their data assimilation systems. Because of the wide use of operational and reanalysis products (e.g., in process studies, initializing numerical simulations, construction of large-scale forcing datasets for CRMs, etc.), their validity will be examined by comparing a variety of basic and diagnosed fields from two operational analyses (ECMWF and NCEP) to similar analyses based solely on sounding observations. Particular attention will be given to the vertical structures of apparent heating (Q1) and drying (Q2) from the operational analyses (OA), which are strongly influenced by cumulus parameterizations, a source of model infidelity. Preliminary results indicate that the OA products did a reasonable job at capturing the mean and temporal characteristics of convection during the DYNAMO enhanced observing period, which included the passage of two significant MJO events during the October-November 2011 period. For example, temporal correlations between Q2-budget derived rainfall from the OA products and that estimated from the TRMM satellite (i.e., the 3B42V7 product) were greater than 0.9 over the Northern Sounding Array of DYNAMO. However closer inspection of the budget profiles show notable differences between the OA products and the sounding-derived results in low-level (surface to 700 hPa) heating and drying structures. This presentation will examine these differences and

  4. Stable isotopic analyses in paleoclimatic reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Wigand, P.E. [Univ. and Community College System of Nevada, Reno, NV (United States)

    1995-09-01

    Most traditional paleoclimatic proxy data have inherent time lags between climatic input and system response that constrain their use in accurate reconstruction of paleoclimate chronology, scaling of its variability, and the elucidation of the processes that determine its impact on the biotic and abiotic environment. With the exception of dendroclimatology, and studies of short-lived organisms and pollen recovered from annually varved lacustrine sediments, significant periods of time ranging from years, to centuries, to millennia may intervene between climate change and its first manifestation in paleoclimatic proxy data records. Reconstruction of past climate through changes in plant community composition derived from pollen sequences and plant remains from ancient woodrat middens, wet environments and dry caves all suffer from these lags. However, stable isotopic analyses can provide more immediate indication of biotic response to climate change. Evidence of past physiological response of organisms to changes in effective precipitation as climate varies can be provided by analyses of the stable isotopic content of plant macrofossils from various contexts. These analyses consider variation in the stable isotopic (hydrogen, oxygen and carbon) content of plant tissues as it reflects (1) past global or local temperature through changes in meteoric (rainfall) water chemistry in the case of the first two isotopes, and (2) plant stress through changes in plant respiration/transpiration processes under differing water availability, and varying atmospheric CO, composition (which itself may actually be a net result of biotic response to climate change). Studies currently being conducted in the Intermountain West indicate both long- and short-term responses that when calibrated with modem analogue studies have the potential of revealing not only the timing of climate events, but their direction, magnitude and rapidity.

  5. IDEA: Interactive Display for Evolutionary Analyses

    Directory of Open Access Journals (Sweden)

    Carlton Jane M

    2008-12-01

    Full Text Available Abstract Background The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints and other molecular evolution variables of interest an increasingly important approach to addressing broad evolutionary questions. Two of the programs most widely used for this purpose are codeml and baseml, parts of the PAML (Phylogenetic Analysis by Maximum Likelihood suite. A significant drawback of these programs is their lack of a graphical user interface, which can limit their user base and considerably reduce their efficiency. Results We have developed IDEA (Interactive Display for Evolutionary Analyses, an intuitive graphical input and output interface which interacts with PHYLIP for phylogeny reconstruction and with codeml and baseml for molecular evolution analyses. IDEA's graphical input and visualization interfaces eliminate the need to edit and parse text input and output files, reducing the likelihood of errors and improving processing time. Further, its interactive output display gives the user immediate access to results. Finally, IDEA can process data in parallel on a local machine or computing grid, allowing genome-wide analyses to be completed quickly. Conclusion IDEA provides a graphical user interface that allows the user to follow a codeml or baseml analysis from parameter input through to the exploration of results. Novel options streamline the analysis process, and post-analysis visualization of phylogenies, evolutionary rates and selective constraint along protein sequences simplifies the interpretation of results. The integration of these functions into a single tool eliminates the need for lengthy data handling and parsing, significantly expediting access to global patterns in the data.

  6. Comparison of elastic and inelastic analyses

    International Nuclear Information System (INIS)

    The use of inelastic analysis methods instead of the traditional elastic analysis methods in the design of radioactive material (RAM) transport packagings leads to a better understanding of the response of the package to mechanical loadings. Thus, better assessment of the containment, thermal protection, and shielding integrity of the package after a structure accident event can be made. A more accurate prediction of the package response can lead to enhanced safety and also allow for a more efficient use of materials, possibly leading to a package with higher capacity or lower weight. This paper discusses the advantages and disadvantages of using inelastic analysis in the design of RAM shipping packages. The use of inelastic analysis presents several problems to the package designer. When using inelastic analysis the entire nonlinear response of the material must be known, including the effects of temperature changes and strain rate. Another problem is that there currently is not an acceptance criteria for this type of analysis that is approved by regulatory agencies. Inelastic analysis acceptance criteria based on failure stress, failure strain , or plastic energy density could be developed. For both elastic and inelastic analyses it is also important to include other sources of stress in the analyses, such as fabrication stresses, thermal stresses, stresses from bolt preloading, and contact stresses at material interfaces. Offsetting these added difficulties is the improved knowledge of the package behavior. This allows for incorporation of a more uniform margin of safety, which can result in weight savings and a higher level of confidence in the post-accident configuration of the package. In this paper, comparisons between elastic and inelastic analyses are made for a simple ring structure and for a package to transport a large quantity of RAM by rail (rail cask) with lead gamma shielding to illustrate the differences in the two analysis techniques

  7. FEM-ANALYSE AV INDUSTRIELL ALUMINIUMSPROFILEKSTRUDERING

    OpenAIRE

    Christenssen, Wenche

    2014-01-01

    Avhandlingen er skrevet for å øke forståelsen og kunnskapen rundt materialflyt ved ekstruderingav komplekse og tynnvegde aluminiumprofiler. Det gjennomgås også hvordan ujevn materialflyt utav en matrise kan avbalanseres ved bruk av forkammer.Rapporten tar for seg oppbygning av modeller og simulering for to forskjellige profilgeometrier.Det første profilet er et U-profil som det tidligere er gjort analyser av ved bruk av modellmateriale.Dette ble gjort i en Diplom...

  8. Erregerspektrum bei tiefen Halsinfektionen: Eine retrospektive Analyse

    OpenAIRE

    Sömmer, C; Haid, M; Hommerich, C; Laskawi, R; Canis, M; Matthias, C

    2014-01-01

    Einleitung: Tiefe Halsinfektionen zählen zu den gefährlichsten Erkrankungen in der HNO-Heilkunde. Diese Analyse gibt einen Überblick über die Mikrobiologie tiefer Halsinfektionen und Einflussfaktoren, die zu einer Änderung des Keimspektrums führen können. Methoden: Von Januar 2002 bis Dezember 2012 wurden 63 Patienten mit tiefen Halsinfektionen in der HNO-Klinik der Universitätsmedizin Göttingen behandelt. Es wurden intraoperative Abstriche entnommen. Die Inzidenz der häufigsten Erreger wur...

  9. Use of Geospatial Analyses for Semantic Reasoning

    OpenAIRE

    Karmacharya, Ashish; Cruz, Christophe; Boochs, Frank; Marzani, Franck

    2010-01-01

    International audience This work focuses on the integration of the spatial analyses for semantic reasoning in order to compute new axioms of an existing OWL ontology. To make it concrete, we have defined Spatial Built-ins, an extension of existing Built-ins of the SWRL rule language. It permits to run deductive rules with the help of a translation rule engine. Thus, the Spatial SWRL rules are translated to standard SWRL rules. Once the spatial functions of the Spatial SWRL rules are comput...

  10. Hybrid Logical Analyses of the Ambient Calculus

    DEFF Research Database (Denmark)

    Bolander, Thomas; Hansen, Rene Rydhof

    2010-01-01

    In this paper, hybrid logic is used to formulate three control flow analyses for Mobile Ambients, a process calculus designed for modelling mobility. We show that hybrid logic is very well-suited to express the semantic structure of the ambient calculus and how features of hybrid logic can...... be exploited to reduce the "administrative overhead" of the analysis specification and thus simplify it. Finally, we use HyLoTab, a fully automated theorem prover for hybrid logic, both as a convenient platform for a prototype implementation as well as to formally prove the correctness of the analysis. (C...

  11. Analyses of containment structures with corrosion damage

    International Nuclear Information System (INIS)

    Corrosion damage to a nuclear power plant containment structure can degrade the pressure capacity of the vessel. For the low-carbon, low- strength steels used in containments, the effect of corrosion on material properties is discussed. Strain-to-failure tests, in uniaxial tension, have been performed on corroded material samples. Results were used to select strain-based failure criteria for corroded steel. Using the ABAQUS finite element analysis code, the capacity of a typical PWR Ice Condenser containment with corrosion damage has been studied. Multiple analyses were performed with the locations of the corrosion the containment, and the amount of corrosion varied in each analysis

  12. En analyse av Yoga-kundalini-upanisad

    OpenAIRE

    2006-01-01

    Avhandlingen En analyse av Yoga-kundalini-upanisad bygger på den indiske asketen Narayanaswamy Aiyers engelske oversettelse av Yoga-kundalini-upanisad, utgitt i Thirty Minor Upanisad-s, Including the Yoga Upanisad-s (Oklahoma, Santarasa Publications, 1980). Denne hinduistiske teksten er omtalt som en av de 21 yoga-upanishadene, den åttisjette av de 108 klassiske upanishadene, og utgjør en del av tekstkorpuset Krsna-Yajurveda. Teksten fungerer som en manual i øvelser fra disiplinene hathayoga,...

  13. Introduction: Analysing Emotion and Theorising Affect

    Directory of Open Access Journals (Sweden)

    Peta Tait

    2016-08-01

    Full Text Available This discussion introduces ideas of emotion and affect for a volume of articles demonstrating the scope of approaches used in their study within the humanities and creative arts. The volume offers multiple perspectives on emotion and affect within 20th-century and 21st-century texts, arts and organisations and their histories. The discussion explains how emotion encompasses the emotions, emotional feeling, sensation and mood and how these can be analysed particularly in relation to literature, art and performance. It briefly summarises concepts of affect theory within recent approaches before introducing the articles.

  14. Fully Coupled FE Analyses of Buried Structures

    Directory of Open Access Journals (Sweden)

    James T. Baylot

    1994-01-01

    Full Text Available Current procedures for determining the response of buried structures to the effects of the detonation of buried high explosives recommend decoupling the free-field stress analysis from the structure response analysis. A fully coupled (explosive–soil structure finite element analysis procedure was developed so that the accuracies of current decoupling procedures could be evaluated. Comparisons of the results of analyses performed using this procedure with scale-model experiments indicate that this finite element procedure can be used to effectively evaluate the accuracies of the methods currently being used to decouple the free-field stress analysis from the structure response analysis.

  15. Large scale breeder reactor pump dynamic analyses

    International Nuclear Information System (INIS)

    The lateral natural frequency and vibration response analyses of the Large Scale Breeder Reactor (LSBR) primary pump were performed as part of the total dynamic analysis effort to obtain the fabrication release. The special features of pump modeling are outlined in this paper. The analysis clearly demonstrates the method of increasing the system natural frequency by reducing the generalized mass without significantly changing the generalized stiffness of the structure. Also, a method of computing the maximum relative and absolute steady state responses and associated phase angles at given locations is provided. This type of information is very helpful in generating response versus frequency and phase angle versus frequency plots

  16. BIFURCATION ANALYSIS OF EQUILIBRIUM POINT IN TWO NODE POWER SYSTEM

    Directory of Open Access Journals (Sweden)

    Halima Aloui

    2014-01-01

    Full Text Available This study presents a study of bifurcation in a dynamic power system model. It becomes one of the major precautions for electricity suppliers and these systems must maintain a steady state in the neighborhood of the operating points. We study in this study the dynamic stability of two node power systems theory and the stability of limit cycles emerging from a subcritical or supercritical Hopf bifurcation by computing the first Lyapunov coefficient. The MATCONT package of MATLAB was used for this study and detailed numerical simulations presented to illustrate the types of dynamic behavior. Results have proved the analyses for the model exhibit dynamical bifurcations, including Hopf bifurcations, Limit point bifurcations, Zero Hopf bifurcations and Bagdanov-taknes bifurcations.

  17. Banks-Zaks fixed point analysis in momentum subtraction schemes

    CERN Document Server

    Gracey, J A

    2015-01-01

    We analyse the critical exponents relating to the quark mass anomalous dimension and beta-function at the Banks-Zaks fixed point in Quantum Chromodynamics (QCD) in a variety of representations for the quark in the momentum subtraction (MOM) schemes of Celmaster and Gonsalves. For a specific range of values of the number of quark flavours, estimates of the exponents appear to be scheme independent. Using the recent five loop modified minimal subtraction (MSbar) scheme quark mass anomalous dimension and estimates of the fixed point location we estimate the associated exponent as 0.263-0.268 for the SU(3) colour group and 12 flavours when the quarks are in the fundamental representation.

  18. Low-energy point source searches with IceCube

    Directory of Open Access Journals (Sweden)

    Euler Sebastian

    2016-01-01

    Full Text Available Due to the overwhelming background of atmospheric muons, the traditional IceCube point source search in the Southern Hemisphere is mainly sensitive to neutrinos with energies above 100TeV. A new approach focuses on events starting inside the instrumented volume. By utilizing different veto techniques we are able to significantly reduce the energy threshold and can now for the first time explore the entire Southern Hemisphere at neutrino energies as low as 100GeV. We present the results of two analyses targeting slightly different energy ranges. Both use one year of data taken with the completed IceCube detector in 2011/12.

  19. Analysis of sludge from Indian Point 3. Final report

    International Nuclear Information System (INIS)

    This report describes detailed chemical anlaysis of samples of Indian Point 3 PWR steam generator sludge. The sludge was found to be primarily made of oxides of iron with percentage amounts of copper metal, cuprous oxide, and sand. In addition, Zn, Ni, and Al were observed at the 1 to 2% level. Other elements observed at less than 1% included Mn, Mg, Pb, Ca, B, P, S, Ti, Cr, Zr, Mo, and Sn. An unexpected finding was that it contained 2% of ion exchange resins. Both an anion and a cation resin fraction were separated. Their separation and subsequent analysis is discussed in detail, and the entire set of chemical analyses is described

  20. Pro SharePoint 2010 Search

    CERN Document Server

    Noble, J; Bakman-Mikalski, Dan

    2011-01-01

    Pro SharePoint 2010 Search gives you expert advice on planning, deploying and customizing searches in SharePoint 2010. Drawing on the authors' extensive experience of working with real-world SharePoint deployments, this book teaches everything you'll need to know to create well-designed SharePoint solutions that always keep the end-user's experience in mind. Increase your search efficiency with SharePoint 2010's search functionality: extend the search user interface using third-party tools, and utilize analytics to improve relevancy. This practical hands-on book is a must-have resource for any

  1. Pro SharePoint 2013 administration

    CERN Document Server

    Garrett, Robert

    2013-01-01

    Pro SharePoint 2013 Administration is a practical guide to SharePoint 2013 for intermediate to advanced SharePoint administrators and power users, covering the out-of-the-box feature set and capabilities of Microsoft's collaboration and business productivity platform. SharePoint 2013 is an incredibly complex product, with many moving parts, new features, best practices, and 'gotchas.' Author Rob Garrett distills SharePoint's portfolio of features, capabilities, and utilities into an in-depth professional guide-with no fluff and copious advice-that is designed from scratch to be the manual Micr

  2. Equipartitioning and balancing points of polygons

    Directory of Open Access Journals (Sweden)

    Shunmugam Pillay

    2010-07-01

    Full Text Available The centre of mass G of a triangle has the property that the rays to the vertices from G sweep out triangles having equal areas. We show that such points, termed equipartitioning points in this paper, need not exist in other polygons. A necessary and sufficient condition for a quadrilateral to have an equipartitioning point is that one of its diagonals bisects the other. The general theorem, namely, necessary and sufficient conditions for equipartitioning points for arbitrary polygons to exist, is also stated and proved. When this happens, they are in general, distinct from the centre of mass. In parallelograms, and only in them, do the two points coincide.

  3. SharePoint 2013 for dummies

    CERN Document Server

    Withee, Ken

    2013-01-01

    The bestselling guide on running SharePoint, now updated to cover all the new features of SharePoint 2013 SharePoint Portal Server is an essential part of the enterprise infrastructure for many businesses. Building on the success of previous versions of SharePoint For Dummies, this new edition covers all the latest features of SharePoint 2013 and provides you with an easy-to-understand resource for making the most of all that this version has to offer. You'll learn how to get a site up and running, branded, and populated with content, workflow, and management. In addition, t

  4. Point Pattern Matching Algorithm for Planar Point Sets under Euclidean Transform

    Directory of Open Access Journals (Sweden)

    Xiaoyun Wang

    2012-01-01

    Full Text Available Point pattern matching is an important topic of computer vision and pattern recognition. In this paper, we propose a point pattern matching algorithm for two planar point sets under Euclidean transform. We view a point set as a complete graph, establish the relation between the point set and the complete graph, and solve the point pattern matching problem by finding congruent complete graphs. Experiments are conducted to show the effectiveness and robustness of the proposed algorithm.

  5. Industry Analyses for a case company

    OpenAIRE

    Aalto, Miikka

    2016-01-01

    The thesis is investigating three countries from industry and market point of view by using various theoretical tools and data to complete the analysis. The purpose of the thesis is to find out what kind of sales methods should the case company apply to the selected countries and why, in order to increase sales and profit. In Italy and Spain the case company sees better sales potential than there currently is, and in Belgium the possibility of lower costs is high. The assessment has been cond...

  6. Hitchhikers’ guide to analysing bird ringing data

    Directory of Open Access Journals (Sweden)

    Harnos Andrea

    2015-12-01

    Full Text Available Bird ringing datasets constitute possibly the largest source of temporal and spatial information on vertebrate taxa available on the globe. Initially, the method was invented to understand avian migration patterns. However, data deriving from bird ringing has been used in an array of other disciplines including population monitoring, changes in demography, conservation management and to study the effects of climate change to name a few. Despite the widespread usage and importance, there are no guidelines available specifically describing the practice of data management, preparation and analyses of ringing datasets. Here, we present the first of a series of comprehensive tutorials that may help fill this gap. We describe in detail and through a real-life example the intricacies of data cleaning and how to create a data table ready for analyses from raw ringing data in the R software environment. Moreover, we created and present here the R package; ringR, designed to carry out various specific tasks and plots related to bird ringing data. Most methods described here can also be applied to a wide range of capture-recapture type data based on individual marking, regardless to taxa or research question.

  7. Transportation systems analyses: Volume 1: Executive Summary

    Science.gov (United States)

    1993-05-01

    The principal objective of this study is to accomplish a systems engineering assessment of the nation's space transportation infrastructure. This analysis addresses the necessary elements to perform man delivery and return, cargo transfer, cargo delivery, payload servicing, and the exploration of the Moon and Mars. Specific elements analyzed, but not limited to, include the Space Exploration Initiative (SEI), the National Launch System (NLS), the current expendable launch vehicle (ELV) fleet, ground facilities, the Space Station Freedom (SSF), and other civil, military and commercial payloads. The performance of this study entails maintaining a broad perspective on the large number of transportation elements that could potentially comprise the U.S. space infrastructure over the next several decades. To perform this systems evaluation, top-level trade studies are conducted to enhance our understanding of the relationships between elements of the infrastructure. This broad 'infrastructure-level perspective' permits the identification of preferred infrastructures. Sensitivity analyses are performed to assure the credibility and usefulness of study results. This executive summary of the transportation systems analyses (TSM) semi-annual report addresses the SSF logistics resupply. Our analysis parallels the ongoing NASA SSF redesign effort. Therefore, there could be no SSF design to drive our logistics analysis. Consequently, the analysis attempted to bound the reasonable SSF design possibilities (and the subsequent transportation implications). No other strategy really exists until after a final decision is rendered on the SSF configuration.

  8. Learner as Statistical Units of Analyses

    Directory of Open Access Journals (Sweden)

    Vivek Venkatesh

    2011-01-01

    Full Text Available Educational psychologists have researched the generality and specificity of metacognitive monitoring in the context of college-level multiple-choice tests, but fairly little is known as to how learners monitor their performance on more complex academic tasks. Even lesser is known about how monitoring proficiencies such as discrimination and bias might be related to key self-regulatory processes associated with task understanding. This quantitative study explores the relationship between monitoring proficiencies and task understanding in 39 adult learners tackling ill-structured writing tasks for a graduate “theories of e-learning” course. Using learner as unit of analysis, the generality of monitoring is confirmed through intra-measure correlation analyses while facets of its specificity stand out due to the absence of inter-measure correlations. Unsurprisingly, learner-based correlational and repeated measures analyses did not reveal how monitoring proficiencies and task understanding might be related. However, using essay as unit of analysis, ordinal and multinomial regressions reveal how monitoring influences different levels of task understanding. Results are interpreted not only in light of novel procedures undertaken in calculating performance prediction capability but also in the application of essay-based, intra-sample statistical analysis that reveal heretofore unseen relationships between academic self-regulatory constructs.

  9. Hierarchical regression for analyses of multiple outcomes.

    Science.gov (United States)

    Richardson, David B; Hamra, Ghassan B; MacLehose, Richard F; Cole, Stephen R; Chu, Haitao

    2015-09-01

    In cohort mortality studies, there often is interest in associations between an exposure of primary interest and mortality due to a range of different causes. A standard approach to such analyses involves fitting a separate regression model for each type of outcome. However, the statistical precision of some estimated associations may be poor because of sparse data. In this paper, we describe a hierarchical regression model for estimation of parameters describing outcome-specific relative rate functions and associated credible intervals. The proposed model uses background stratification to provide flexible control for the outcome-specific associations of potential confounders, and it employs a hierarchical "shrinkage" approach to stabilize estimates of an exposure's associations with mortality due to different causes of death. The approach is illustrated in analyses of cancer mortality in 2 cohorts: a cohort of dioxin-exposed US chemical workers and a cohort of radiation-exposed Japanese atomic bomb survivors. Compared with standard regression estimates of associations, hierarchical regression yielded estimates with improved precision that tended to have less extreme values. The hierarchical regression approach also allowed the fitting of models with effect-measure modification. The proposed hierarchical approach can yield estimates of association that are more precise than conventional estimates when one wishes to estimate associations with multiple outcomes. PMID:26232395

  10. Analyses of containment structures with corrosion damage

    Energy Technology Data Exchange (ETDEWEB)

    Cherry, J.L. [Sandia National Labs., Albuquerque, NM (United States)

    1997-01-01

    Corrosion damage that has been found in a number of nuclear power plant containment structures can degrade the pressure capacity of the vessel. This has prompted concerns regarding the capacity of corroded containments to withstand accident loadings. To address these concerns, finite element analyses have been performed for a typical PWR Ice Condenser containment structure. Using ABAQUS, the pressure capacity was calculated for a typical vessel with no corrosion damage. Multiple analyses were then performed with the location of the corrosion and the amount of corrosion varied in each analysis. Using a strain-based failure criterion, a {open_quotes}lower bound{close_quotes}, {open_quotes}best estimate{close_quotes}, and {open_quotes}upper bound{close_quotes} failure level was predicted for each case. These limits were established by: determining the amount of variability that exists in material properties of typical containments, estimating the amount of uncertainty associated with the level of modeling detail and modeling assumptions, and estimating the effect of corrosion on the material properties.

  11. Ethics of cost analyses in medical education.

    Science.gov (United States)

    Walsh, Kieran

    2013-11-01

    Cost analyses in medical education are rarely straightforward, and rarely lead to clear-cut conclusions. Occasionally they do lead to clear conclusions but even when that happens, some stakeholders will ask difficult but valid questions about what to do following cost analyses-specifically about distributive justice in the allocation of resources. At present there are few or no debates about these issues and rationing decisions that are taken in medical education are largely made subconsciously. Distributive justice 'concerns the nature of a socially just allocation of goods in a society'. Inevitably there is a large degree of subjectivity in the judgment as to whether an allocation is seen as socially just or ethical. There are different principles by which we can view distributive justice and which therefore affect the prism of subjectivity through which we see certain problems. For example, we might say that distributive justice at a certain institution or in a certain medical education system operates according to the principle that resources must be divided equally amongst learners. Another system may say that resources should be distributed according to the needs of learners or even of patients. No ethical system or model is inherently right or wrong, they depend on the context in which the educator is working. PMID:24203859

  12. Analyses of containment structures with corrosion damage

    International Nuclear Information System (INIS)

    Corrosion damage that has been found in a number of nuclear power plant containment structures can degrade the pressure capacity of the vessel. This has prompted concerns regarding the capacity of corroded containments to withstand accident loadings. To address these concerns, finite element analyses have been performed for a typical PWR Ice Condenser containment structure. Using ABAQUS, the pressure capacity was calculated for a typical vessel with no corrosion damage. Multiple analyses were then performed with the location of the corrosion and the amount of corrosion varied in each analysis. Using a strain-based failure criterion, a open-quotes lower boundclose quotes, open-quotes best estimateclose quotes, and open-quotes upper boundclose quotes failure level was predicted for each case. These limits were established by: determining the amount of variability that exists in material properties of typical containments, estimating the amount of uncertainty associated with the level of modeling detail and modeling assumptions, and estimating the effect of corrosion on the material properties

  13. Bioinformatics tools for analysing viral genomic data.

    Science.gov (United States)

    Orton, R J; Gu, Q; Hughes, J; Maabar, M; Modha, S; Vattipally, S B; Wilkie, G S; Davison, A J

    2016-04-01

    The field of viral genomics and bioinformatics is experiencing a strong resurgence due to high-throughput sequencing (HTS) technology, which enables the rapid and cost-effective sequencing and subsequent assembly of large numbers of viral genomes. In addition, the unprecedented power of HTS technologies has enabled the analysis of intra-host viral diversity and quasispecies dynamics in relation to important biological questions on viral transmission, vaccine resistance and host jumping. HTS also enables the rapid identification of both known and potentially new viruses from field and clinical samples, thus adding new tools to the fields of viral discovery and metagenomics. Bioinformatics has been central to the rise of HTS applications because new algorithms and software tools are continually needed to process and analyse the large, complex datasets generated in this rapidly evolving area. In this paper, the authors give a brief overview of the main bioinformatics tools available for viral genomic research, with a particular emphasis on HTS technologies and their main applications. They summarise the major steps in various HTS analyses, starting with quality control of raw reads and encompassing activities ranging from consensus and de novo genome assembly to variant calling and metagenomics, as well as RNA sequencing.

  14. CHEMICAL ANALYSES OF SODIUM SYSTEMS FINAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Greenhalgh, W. O.; Yunker, W. H.; Scott, F. A.

    1970-06-01

    BNWL-1407 summarizes information gained from the Chemical Analyses of Sodium Systems Program pursued by Battelle- Northwest over the period from July 1967 through June 1969. Tasks included feasibility studies for performing coulometric titration and polarographic determinations of oxygen in sodium, and the development of new separation techniques for sodium impurities and their subsequent analyses. The program was terminated ahead of schedule so firm conclusions were not obtained in all areas of the work. At least 40 coulometric titrations were carried out and special test cells were developed for coulometric application. Data indicated that polarographic measurements are theoretically feasible, but practical application of the method was not verified. An emission spectrographic procedure for trace metal impurities was developed and published. Trace metal analysis by a neutron activation technique was shown to be feasible; key to the success of the activation technique was the application of a new ion exchange resin which provided a sodium separation factor of 10{sup 11}. Preliminary studies on direct scavenging of trace metals produced no conclusive results.

  15. ANALYSES ON SYSTEMATIC CONFRONTATION OF FIGHTER AIRCRAFT

    Institute of Scientific and Technical Information of China (English)

    HuaiJinpeng; WuZhe; HuangJun

    2002-01-01

    Analyses of the systematic confrontation between two military forcfes are the highest hierarchy on opera-tional effectiveness study of weapon systema.The physi-cal model for tactical many-on-many engagements of an aerial warfare with heterogeneous figher aircraft is estab-lished.On the basis of Lanchester multivariate equations of square law,a mathematical model corresponding to the established physical model is given.A superiorityh parame-ter is then derived directly from the mathematical model.With view to the high -tech condition of modern war-fare,the concept of superiority parameter which more well and truly reflects the essential of an air-to-air en-gagement is further formulated.The attrition coeffi-cients,which are key to the differential equations,are de-termined by using tactics of random target assignment and air-to-air capability index of the fighter aircraft.Hereby,taking the mathematical model and superiority parameter as cores,calculations amd analyses of complicate systemic problems such as evaluation of battle superiority,prog-mostication of combat process and optimization of colloca-tions have been accomplished.Results indicate that a clas-sical combat theory with its certain recent development has received newer applications in the military operation research for complicated confrontation analysis issues.

  16. Sensitivity in risk analyses with uncertain numbers.

    Energy Technology Data Exchange (ETDEWEB)

    Tucker, W. Troy; Ferson, Scott

    2006-06-01

    Sensitivity analysis is a study of how changes in the inputs to a model influence the results of the model. Many techniques have recently been proposed for use when the model is probabilistic. This report considers the related problem of sensitivity analysis when the model includes uncertain numbers that can involve both aleatory and epistemic uncertainty and the method of calculation is Dempster-Shafer evidence theory or probability bounds analysis. Some traditional methods for sensitivity analysis generalize directly for use with uncertain numbers, but, in some respects, sensitivity analysis for these analyses differs from traditional deterministic or probabilistic sensitivity analyses. A case study of a dike reliability assessment illustrates several methods of sensitivity analysis, including traditional probabilistic assessment, local derivatives, and a ''pinching'' strategy that hypothetically reduces the epistemic uncertainty or aleatory uncertainty, or both, in an input variable to estimate the reduction of uncertainty in the outputs. The prospects for applying the methods to black box models are also considered.

  17. Waste Stream Analyses for Nuclear Fuel Cycles

    Energy Technology Data Exchange (ETDEWEB)

    N. R. Soelberg

    2010-08-01

    A high-level study was performed in Fiscal Year 2009 for the U.S. Department of Energy (DOE) Office of Nuclear Energy (NE) Advanced Fuel Cycle Initiative (AFCI) to provide information for a range of nuclear fuel cycle options (Wigeland 2009). At that time, some fuel cycle options could not be adequately evaluated since they were not well defined and lacked sufficient information. As a result, five families of these fuel cycle options are being studied during Fiscal Year 2010 by the Systems Analysis Campaign for the DOE NE Fuel Cycle Research and Development (FCRD) program. The quality and completeness of data available to date for the fuel cycle options is insufficient to perform quantitative radioactive waste analyses using recommended metrics. This study has been limited thus far to qualitative analyses of waste streams from the candidate fuel cycle options, because quantitative data for wastes from the front end, fuel fabrication, reactor core structure, and used fuel for these options is generally not yet available.

  18. Pointing control for the International Comet Mission

    Science.gov (United States)

    Leblanc, D. R.; Schumacher, L. L.

    1980-01-01

    The design of the pointing control system for the proposed International Comet Mission, intended to fly by Comet Halley and rendezvous with Comet Tempel-2 is presented. Following a review of mission objectives and the spacecraft configuration, design constraints on the pointing control system controlling the two-axis gimballed scan platform supporting the science instruments are discussed in relation to the scientific requirements of the mission. The primary design options considered for the pointing control system design for the baseline spacecraft are summarized, and the design selected, which employs a target-referenced, inertially stabilized control system, is described in detail. The four basic modes of operation of the pointing control subsystem (target acquisition, inertial hold, target track and slew) are discussed as they relate to operations at Halley and Tempel-2. It is pointed that the pointing control system design represents a significant advance in the state of the art of pointing controls for planetary missions.

  19. Les conditions de l’analyse qualitative

    Directory of Open Access Journals (Sweden)

    Pierre Paillé

    2011-07-01

    Full Text Available Les méthodes d’analyse des données qualitatives et le monde informatique étaient faits pour se rencontrer. Et en effet, la question est d’actualité et les outils informatiques nombreux et avancés. Ce phénomène ne saurait s’estomper, d’autant moins que l’analyse des données secondaires connaît en même temps des développements importants. Mais l’attrait pour les logiciels d’analyse peut devenir tel qu’on ne verrait plus trop à quel titre et pour quelles raisons on pourrait s’en passer. L’article tente de cerner une vision et une pratique de l’analyse qualitative qui, dans son essence, ne se prête pas à l’utilisation d’outils informatiques spécialisés. Il situe sa réflexion dans le cadre de la méthodologie qualitative (démarche qualitative, recherche qualitative, analyse qualitative, plus particulièrement au niveau de l’enquête qualitative de terrain.The conditions of qualitative analysisThe methods for analyzing qualitative data and the computer world were meant to meet. And, by that, the question is valid and computer tools numerous and advanced. This phenomenon will not slowdown, especially not since secondary data analysis experiences significant developments. But the attraction for analysis software could develop so that we would not see too much why and for what type of reasons we could part from them. This article attempts to define a vision and a practice of qualitative analysis that, in essence, does not use specialized computer tools. It situates its reflection within qualitative methodology (qualitative approaches, qualitative research, qualitative analysis and moreover in the level of qualitative fieldwork investigation.Las condiciones del análisis cualitativo. Reflexiones sobre la utilización de programas informáticosLos métodos de análisis de los datos cualitativos y el mundo de la informática han nacido para entenderse mutualmente. En efecto, la cuestión es actual y los

  20. Attribute-based point cloud visualization in support of 3-D classification

    Science.gov (United States)

    Zlinszky, András; Otepka, Johannes; Kania, Adam

    2016-04-01

    Despite the rich information available in LIDAR point attributes through full waveform recording, radiometric calibration and advanced texture metrics, LIDAR-based classification is mostly done in the raster domain. Point-based analyses such as noise removal or terrain filtering are often carried out without visual investigation of the point cloud attributes used. This is because point cloud visualization software usually handle only a limited number of pre-defined point attributes and only allow colorizing the point cloud with one of these at a time. Meanwhile, point cloud classification is rapidly evolving, and uses not only the individual attributes but combinations of these. In order to understand input data and output results better, more advanced methods for visualization are needed. Here we propose an algorithm of the OPALS software package that handles visualization of the point cloud together with its attributes. The algorithm is based on the .odm (OPALS data manager) file format that efficiently handles a large number of pre-defined point attributes and also allows the user to generate new ones. Attributes of interest can be visualized individually, by applying predefined or user-generated palettes in a simple .xml format. The colours of the palette are assigned to the points by setting the respective Red, Green and Blue attributes of the point to result in the colour pre-defined by the palette for the corresponding attribute value. The algorithm handles scaling and histogram equalization based on the distribution of the point attribute to be considered. Additionally, combinations of attributes can be visualized based on RBG colour mixing. The output dataset can be in any standard format where RGB attributes are supported and visualized with conventional point cloud viewing software. Viewing the point cloud together with its attributes allows efficient selection of filter settings and classification parameters. For already classified point clouds, a large