WorldWideScience

Sample records for cis opinion surveys

  1. Survey Methods, Traditional, Public Opinion Polling

    DEFF Research Database (Denmark)

    Elmelund-Præstekær, Christian; Hopmann, David Nicolas; Pedersen, Rasmus Tue

    2017-01-01

    Traditional public opinion polls are surveys in which a random sample of a given population is asked questions about their attitudes, knowledge, or behavior. If conducted properly, the answers from such surveys are approximately representative of the entire population. Traditional public opinion...... polling is typically based on four different methods of data gathering, or combinations hereof: face-to-face, postal surveys, phone surveys, and web surveys. Given that opinion polls are based on a sample, we cannot be sure that the sample reflects public opinion perfectly, however—even if randomness...... is perfect. Moreover, responses may be highly dependent on the contextual information provided with the question. Also, it may be difficult to capture past or complex causes of attitudes or behavior. In short, surveys are a precise way of measuring public opinion, but they do not come without challenges....

  2. Perception of the Environment and its Position among the Concerns of Spanish People: Analysis of CIS Opinion Surveys; La Percepcion del Medio Ambiente y su Posicionamiento entre las Preocupaciones de los Espanoles: Analisis de los Barometros del CIS

    Energy Technology Data Exchange (ETDEWEB)

    Munoz van den Eynde, A.; Sola Farre, R

    2007-09-27

    Starting from the hypothesis that environmental concern is socially built, dynamic and permeable to current situation and the news, this work is two aimed: a) To study potential differences in environmental concern due to socio demographic variables, in order to define an environmentally concerned profile; b) To analyze the evolution of this concern in Spanish society for the last seven years. To archive this purposes, data originating in Spanish sociological research centre (CIS) opinion surveys has been used. No significant relation among socio demographic variables and environmental concern has been found. Percentage of people concerned about environment is quite low (about 2%), above all in relation to other issues as economic situation, terrorism or immigration. However, this percentage has increased remarkably when some environmentally threatening event has been present (as forest fi res, or Prestige oil spill). It has also been detected that this concern is gradually increasing, possibly due to growing knowledge of economic and technical development and environmental damage relation. Environmental concern is different according to which territorial level people has in mind when reporting their opinion (world, country or region). (Author) 31 refs.

  3. Opinion survey on energy and climate in 2013

    International Nuclear Information System (INIS)

    Martin, Jean-Philippe

    2013-08-01

    This issue comments the results of a survey on the opinion of French people on the reality of climate change (for the whole population and with respect to age), on the opinion of French people on nuclear energy (in relationship with the opinion on climate change, globally in terms of benefit or drawback with evolution of the opinion since 1994), on the feeling of having suffered from the cold during the winter of 2012-2013, on the dwelling temperature in winter, and on the opinion on energy price

  4. A Survey of Current Computer Information Science (CIS) Students.

    Science.gov (United States)

    Los Rios Community Coll. District, Sacramento, CA. Office of Institutional Research.

    This document is a survey designed to be completed by current students of Computer Information Science (CIS) in the Los Rios Community College District (LRCCD), which consists of three community colleges: American River College, Cosumnes River College, and Sacramento City College. The students are asked about their educational goals and how…

  5. 2003/04 public opinion survey Nuclear energy - the present and the future

    International Nuclear Information System (INIS)

    Trontl, K.

    2004-01-01

    During the academic years 2000/01, 2001/02 and 2002/03 the Croatian Nuclear Society Young Generation Network (CYGN) carried out public opinion surveys among student population of around 600 individuals age 18-20. The results of the surveys have shown that the participants are rather ignorant on nuclear issues but still very negative, especially towards nuclear power plants and radioactive waste disposal sites with emphasized Not In My Back Yard (NIMBY) syndrome. As a part of the active involvement of CYGN members in upgrading of the positive public opinion, especially, young generations towards nuclear issues, a brochure on radioactivity has been prepared and distributed at the beginning of the 2002/03 school year to third and fourth graders in high schools. Hopefully a part of the 2003/04 academic year, freshman student population received a brochure during their high school education. Therefore, CYGN decided to carry out 2003/04 public opinion survey Nuclear Energy - the Present and the Future in order to investigate the effects of the brochure on student opinions on nuclear subjects. The results of the survey should also provide information on the quality of the distributed materials, as well as the quality of the distribution strategy. The results and the analyses of the 2003/04 public opinion survey, as well as the comparison of the results with the previous surveys are presented in this paper.(author)

  6. Continuous Opinion Dynamics Under Bounded Confidence:. a Survey

    Science.gov (United States)

    Lorenz, Jan

    Models of continuous opinion dynamics under bounded confidence have been presented independently by Krause and Hegselmann and by Deffuant et al. in 2000. They have raised a fair amount of attention in the communities of social simulation, sociophysics and complexity science. The researchers working on it come from disciplines such as physics, mathematics, computer science, social psychology and philosophy. In these models agents hold continuous opinions which they can gradually adjust if they hear the opinions of others. The idea of bounded confidence is that agents only interact if they are close in opinion to each other. Usually, the models are analyzed with agent-based simulations in a Monte Carlo style, but they can also be reformulated on the agent's density in the opinion space in a master equation style. The contribution of this survey is fourfold. First, it will present the agent-based and density-based modeling frameworks including the cases of multidimensional opinions and heterogeneous bounds of confidence. Second, it will give the bifurcation diagrams of cluster configuration in the homogeneous model with uniformly distributed initial opinions. Third, it will review the several extensions and the evolving phenomena which have been studied so far, and fourth it will state some open questions.

  7. COMPENDIUM: SURVEYS EVALUATING KNOWLEDGE AND OPINIONS CONCERNING HYDROGEN AND FUEL CELL TECHNOLOGIES

    Energy Technology Data Exchange (ETDEWEB)

    Truett, Lorena Faith [ORNL; Cooper, Christy [U.S. Department of Energy; Schmoyer, Richard L [ORNL

    2008-10-01

    This compendium updates a 2003 literature review of surveys of knowledge and opinions of hydrogen and fuel cell technologies. Its purpose is to ensure that results of comparable surveys are considered in surveys conducted by the U.S. Department of Energy (DOE). Over twice as many studies related to the DOE survey have been published since 2003 than prior to that date. The fact that there have been significantly more studies implies that there have been further demonstration projects and/or increased interest in hydrogen and fuel cell technologies. The primary findings of these 15 new surveys, all of which were conducted in Europe (E) or North America (NA), to the DOE surveys are as follows: 1.Respondents who are more educated are more accepting of hydrogen technologies (NA). 2.Respondents who are more knowledgeable about hydrogen and/or fuel cells are more accepting of hydrogen technologies (E, NA). 3.When asked about issues of trust, respondents generally expressed distrust of the government or political parties but trusted scientists and environmental protection organizations (E). 4.Technical knowledge about hydrogen and fuel cell technologies is low (E, NA). 5.Respondents may express opinions about a technology even when they are lacking in knowledge of that technology (E). 6.Women and men have different priorities when deciding on an automobile purchase (E). 7.Public acceptance to hydrogen is vulnerable to perceptions of decreased safety (E, NA). 8.Public acceptance to hydrogen is vulnerable to perceptions of increased cost (E, NA). The DOE surveys are similar to surveys that examine technical knowledge of hydrogen and fuel cell technologies, although the technical questions are certainly different. The DOE surveys are also similar to the opinion surveys in that they address many of the same issues, such as safety, sources of energy information, or trust. There are many differences between the surveys reviewed in this compendium and the DOE surveys. The

  8. Survey data reflecting popular opinions of the causes and mitigation of climate change

    OpenAIRE

    Thompson, Jonathan E.

    2017-01-01

    The data presented within this manuscript reports the results of a 20-question opinion survey concerning popular beliefs regarding the causes of and possible mitigation of climate change. The results and opinions from 746 survey respondents are presented. The data reflects certain misconceptions of climate change, and is useful for investigators to begin forming opinions of the public's knowledge regarding the potentially inflammatory topics of climate change, greenhouse gases, and geo-engine...

  9. Survey data reflecting popular opinions of the causes and mitigation of climate change.

    Science.gov (United States)

    Thompson, Jonathan E

    2017-10-01

    The data presented within this manuscript reports the results of a 20-question opinion survey concerning popular beliefs regarding the causes of and possible mitigation of climate change. The results and opinions from 746 survey respondents are presented. The data reflects certain misconceptions of climate change, and is useful for investigators to begin forming opinions of the public's knowledge regarding the potentially inflammatory topics of climate change, greenhouse gases, and geo-engineering.

  10. More than 30 years of opinion of French people on nuclear risks - Special release of the 2012 IRSN opinion survey

    International Nuclear Information System (INIS)

    El Jammal, Marie-Helene; Rollinger, Francois; Mur, Emmanuelle; Schuler, Matthieu; Tchernia, Jean-Francois

    2013-01-01

    Illustrated by many graphs and tables, this report comments and discusses the evolution of opinion surveys performed in France on the perception of nuclear risks through thirty annual IRSN opinion surveys. It appears that the opinion on nuclear is rather steady, and that French people have a rather rational perception of risk hierarchy. The first part outlines that unemployment is the main concern for French people, and that environmental concerns depend on current events. The second part analyses the perception of the nuclear risk with respect to other societal concerns and to other risks, and discusses the evolution of opinion from a quantitative to a qualitative sensitivity. The third part addresses the representations people have of nuclear activities and how they challenge the reality: perception of nuclear plants and of radioactive wastes, fear of a serious accident. The last part deals with issues related to responsibilities, abilities and governance: how actors of nuclear risk management are perceived, and expectations in terms of transparency and opinion plurality

  11. FY15 Djibouti Country Opinion Survey Report

    OpenAIRE

    World Bank Group

    2015-01-01

    The Country Opinion Survey in Djibouti assists the World Bank Group (WBG) in gaining a better understanding of how stakeholders in Djibouti perceive the WBG. It provides the WBG with systematic feedback from national and local governments, multilateral/bilateral agencies, media, academia, the private sector, and civil society in Djibouti on 1) their views regarding the general environment ...

  12. FY16 Honduras Country Opinion Survey Report

    OpenAIRE

    World Bank Group

    2016-01-01

    The Country Opinion Survey in Honduras assists the World Bank Group (WBG) in gaining a better understanding of how stakeholders in Honduras perceive the WBG. It provides the WBG with systematic feedback from national and local governments, multilateral/bilateral agencies, media, academia, the private sector, and civil society in Honduras on 1) their views regarding the general environment ...

  13. An exploratory survey of male and female learner opinions on ...

    African Journals Online (AJOL)

    An exploratory survey was undertaken to determine whether secondary school learners have certain preferences regarding the biology they study at school and whether learners from co-educational and single-sex schools hold the same opinions. A survey schedule comprising two components was developed. The first ...

  14. FY16 Brazil Country Opinion Survey Report

    OpenAIRE

    World Bank Group

    2016-01-01

    The Country Opinion Survey in Brazil assists the World Bank Group (WBG) in gaining a better understanding of how stakeholders in Brazil perceive the WBG. It provides the WBG with systematic feedback from national and local governments, multilateral/bilateral agencies, media, academia, the private sector, and civil society in Brazil on 1) their views regarding the general environment in Bra...

  15. Opinions on Tax Deductions and the Consensus Effect in a Survey-Experiment

    NARCIS (Netherlands)

    van der Heijden, E.C.M.; Nelissen, J.H.M.; Potters, J.J.M.

    2004-01-01

    We present the results of a survey-experiment using a representative sample of the Dutch population in which we relate respondents' opinion about the tax deductibility of mortgages to their estimates about other people's opinion.The experiment employs three treatment variables: monetary incentives,

  16. 2002/03 public opinion survey 'Nuclear Energy - the Present and the Future'

    International Nuclear Information System (INIS)

    Trontl, K.; Gergeta, K.

    2003-01-01

    During the years 2000 and 2002 the Croatian Nuclear Society Young Generation Network carried out public opinion surveys among student population of around 650 individuals age 18-20. The results of the surveys suggested the necessity of a more active involvement of nuclear experts in high school education. Croatian Young Generation Network decided to prepare brochures on different subjects concerning nuclear energy and distribute them to high school students, primarily third and fourth graders. To be able to evaluate the influence of distributed materials, fresh reference data are needed. Therefore, a traditional public opinion survey 'Nuclear Energy - the Present and the Future' has been carried out among faculty student population. (author)

  17. The US Department of Energy hydrogen baseline survey: assessing knowledge and opinions about hydrogen technology

    International Nuclear Information System (INIS)

    Christy Cooper; Tykey Truett; R L Schmoyer

    2006-01-01

    To design and maintain its education program, the United States Department of Energy (DOE) Hydrogen Program conducted a statistically-valid national survey to measure knowledge and opinions of hydrogen among key target audiences. The Hydrogen Baseline Knowledge Survey provides a reference for designing the DOE hydrogen education strategy and will be used in comparisons with future surveys to measure changes in knowledge and opinions over time. The survey sampled four U.S. populations: (1) public; (2) students; (3) state and local government officials; and (4) potential large-scale hydrogen end-users in three business categories. Questions measured technical understanding of hydrogen and opinions about hydrogen safety. Other questions assessed visions of the likelihood of future hydrogen applications and sources of energy information. Several important findings were discovered, including a striking lack of technical understanding across all survey groups, as well as a strong correlation between technical knowledge and opinions about safety: those who demonstrated an understanding of hydrogen technologies expressed the least fear of its safe use. (authors)

  18. Analysis of national representative opinion surveys concerning gestational surrogacy in Japan.

    Science.gov (United States)

    Suzuki, Kohta; Hoshi, Kazuhiko; Minai, Junko; Yanaihara, Takumi; Takeda, Yasuhisa; Yamagata, Zentaro

    2006-05-01

    Although gestational surrogacy offers several advantages, this procedure has given rise to some ethical and legal issues. We aimed to clarify the factors affecting the attitude of the Japanese toward gestational surrogacy. Cross-sectional study. Nationwide opinion surveys concerning assisted reproductive technologies (ART) were carried out in 1999 and 2003. Participants included 2568 and 3647 people from the general public surveyed in 1999 and 2003, respectively (1564 people received only the questionnaire, and 2083 people received a questionnaire and brochure about ART). Multivariate-adjusted odds ratio and 95% confidence interval from logistic regression models for factors affecting the attitude toward gestational surrogacy. In both surveys, approximately half of respondents approved of gestational surrogacy; 20-30% disapproved of the procedure. People with high socioeconomic status clearly expressed their opinion on this issue. A liberal attitude toward gender role promoted approval of gestational surrogacy; a liberal attitude toward family had the opposite effect. Our findings suggest that socioeconomic status affects people's expression of their opinion regarding this issue, while attitudes toward this procedure were influenced by individual belief. Considering socioeconomic status and diversity of individual belief is required for further discussion on this topic.

  19. City College of San Francisco 1997 Sexual Harassment Student Opinion Survey.

    Science.gov (United States)

    City Coll. of San Francisco, CA. Office of Institutional Research, Planning and Grants.

    This document describes the findings of a 1997 sexual harassment student opinion survey conducted at City College of San Francisco. Survey questions were jointly developed by the Sexual Harassment Prevention Sub-Committee of the Diversity Advisory Committee and the Office of Research and Planning, approved by the College Advisory Council, and…

  20. Opinion Polls and Statistical Surveys: What They Really Tell Us

    Indian Academy of Sciences (India)

    from the Indian Statistical. Iastihte in 1986 and the ... any other statistical survey) is the estimation of some un- ... shares are then predicted based on a suitable mathematical model. ..... have some application in opinion polls as well. In the elec ...

  1. Public opinion survey on energy

    International Nuclear Information System (INIS)

    1981-01-01

    The results of a public opinion survey on energy, conducted by Prime Minister's Office from November 26 to December 2, 1980, are described. Of the sampling of 5,000 adults throughout the nation, 4,113 replied the questions. The contents are as follows: awaraness of energy conservation, projection of the future of nuclear power, uneasiness about nuclear power, and energy policies. Concerning the major power generation system of the future, 47% of the people mentioned nuclear energy, followed by 18% mentioned solar energy. As to the future share of nuclear power, 38% favored its increase, 28% its maintaining at the current level, and only 5% wanted its decrease. About the feeling of uneasiness, 56% felt uneasiness and 44% were secure, making it clear that the uneasiness has not yet been eliminated. (J.P.N.)

  2. Public Opinion Survey Data to Measure Sympathy and Support for Islamist Terrorism: A Look at Muslim Opinions on Al Qaeda and IS

    Directory of Open Access Journals (Sweden)

    Alex P. Schmid

    2017-02-01

    Full Text Available This Research Paper seeks to explore what ‘sympathy’ and ‘support’ actually mean when it comes to terrorism. The text addresses some of the problems of public opinion surveys, includes a conceptual discussion and then continues with the presentation of data from public opinion surveys. It notes that opinion polls can be helpful in gauging (verbal support for terrorism but also finds that the questions asked in opinion polls are generally lacking precision while the answers are often influenced by political pressures. When translating (generally low percentages of sympathy and support for al Qaeda and so-called Islamic State in various countries into actual population figures, it emerges that there is a sizeable radical milieu in both Muslim-majority countries and in Western Muslim diasporas, held together by the world wide web of the internet. While large majorities of Muslims in most countries have no love for jihadist extremists, there are more than enough breeding grounds for terrorism. The Research Paper concludes that better instruments for measuring sympathy and support for jihadist terrorism are needed to inform counter-terrorist strategies.

  3. A survey of attitude and opinions of endodontic residents towards regenerative endodontics

    Science.gov (United States)

    Utneja, Shivani; Nawal, Ruchika Roongta; Ansari, Mohammed Irfan; Talwar, Sangeeta; Verma, Mahesh

    2013-01-01

    Aim: The objective of this survey was to study the level of awareness, current state of knowledge and opinions towards regenerative endodontic treatments amongst the endodontic residents of India. Settings and Design: Questionnaire based survey was designed. Materials and Methods: After approval from the organizing committee of 26th Federation of Operative Dentistry of India and 19th Indian Endodontic Society National conference 2011, 200 copies of the questionnaire were circulated amongst the endodontic residents in conservative dentistry and endodontics at various colleges across the country about regenerative endodontic procedures. The survey included profile of the respondents and consisted of 23 questions about their knowledge, attitude and opinions regarding use of these procedures as part of future dental treatment. Results: The survey showed that half the participants (50.6%) had received continued education in stem cells and/or regenerative dental treatments. The majority of participants were of the opinion (86.6%) that regenerative therapy should be incorporated into dentistry, and most of them (88%) were willing to acquire training in learning this new treatment strategy. The results indicated that half of the participants (52.6%) were already using some type of regenerative therapy in their clinical practice; however, with a majority of these limited to use of membranes, scaffolds or bioactive materials. Conclusions: These results reflect that endodontic residents are optimistic about the use of regenerative endodontic procedures; however, a need for more research and training was felt. PMID:23956532

  4. Public opinion polls on nuclear energy

    International Nuclear Information System (INIS)

    Heller, E.D.

    1980-07-01

    Future developments in the attitude towards nuclear energy can not be predicted on account of this public opinion survey. The survey shows just how many different factors influence the attitude towards issues of public and political interst. For this reason in particular, it would be desirable to include such aspects into future surveys. The survey shows that public opinion polls quite often investigate on the ordering party's opinion rather than the pollees opinion. The attempt at making public opinion polls a means of forming political opinions, implying a certain desired opinion to be the majority opinion has brought those polls into disrepute. If real results are not required and manipulation prevails, results are prevented, which must not be blamed on the principle of public opinion polls as such. (orig.) [de

  5. Survey of Expert Opinion on Intelligence: Causes of International Differences in Cognitive Ability Tests.

    Science.gov (United States)

    Rindermann, Heiner; Becker, David; Coyle, Thomas R

    2016-01-01

    Following Snyderman and Rothman (1987, 1988), we surveyed expert opinions on the current state of intelligence research. This report examines expert opinions on causes of international differences in student assessment and psychometric IQ test results. Experts were surveyed about the importance of culture, genes, education (quantity and quality), wealth, health, geography, climate, politics, modernization, sampling error, test knowledge, discrimination, test bias, and migration. The importance of these factors was evaluated for diverse countries, regions, and groups including Finland, East Asia, sub-Saharan Africa, Southern Europe, the Arabian-Muslim world, Latin America, Israel, Jews in the West, Roma (gypsies), and Muslim immigrants. Education was rated by N = 71 experts as the most important cause of international ability differences. Genes were rated as the second most relevant factor but also had the highest variability in ratings. Culture, health, wealth, modernization, and politics were the next most important factors, whereas other factors such as geography, climate, test bias, and sampling error were less important. The paper concludes with a discussion of limitations of the survey (e.g., response rates and validity of expert opinions).

  6. Nuclear installations inspectorate a public opinion survey

    International Nuclear Information System (INIS)

    Lennie, S.E.; Davies, A.G.

    2001-01-01

    HM Nuclear Installations Inspectorate (HMNII) is the regulator responsible for the safety of licensed nuclear sites in the UK. Recognizing the need for public approval on future policy with respect to nuclear waste management, the NII commissioned a public opinion research programme amongst the UK general public. Opinion was sought on a number of issues including attitudes towards the industry in general, perception of nuclear waste and its management, tolerability of risk and attitudes towards current decommissioning plans. In response to the primary objectives of the survey the main findings are: current spontaneous level of concern over the industry in general is low (7%), and lower still for nuclear waste (3%). However, on prompting, 47% of respondents were very concerned about nuclear waste. Top of mind issues of concern about the industry are: nuclear waste; risk of accidents; health risks. Personal risk from nuclear waste is not of overt concern and is significantly less worrisome to respondents than risk from diseases like meningitis or cancer, smoking or road accidents. On being presented with a statement describing current UK decommissioning plans, the sample was generally in favour. However, this issue will require further research. (authors)

  7. [Occupational aspects of emergency medicine practice in Catalonia: the OPENCAT opinion survey].

    Science.gov (United States)

    Jacob, Javier; Gené, Emili; Alonso, Gilberto; Rimbau, Pere; Zorrilla, José; Casarramona, Francesc; Netto, Cristina; Sánchez, Pere; Hernández, Ricard; Escalada, Xavier; Miró, Òscar

    2017-01-01

    To gather information on the contracting and training of members of the Catalan Society of Emergency Medicine (SoCMUE) who work in emergency medicine and services in Catalonia. To survey their opinions on certain aspects of resource availability and working conditions. Cross-sectional descriptive study based on a survey sent to SoCMUE members. We studied the opinions of 5 types of respondent: hospital physicians, out-of-hospital physicians, hospital nurses, out-of-hospital nurses, and emergency medical technicians. Responses were grouped to compare the opinions of physicians and nurses and workers in hospital and prehospital settings. We received 616 responses from 1273 members (48.4% response rate). More physicians than nurses come from outside Catalonia and have contracts specifically linked to emergency care; in addition, physicians have done less postgraduate training in emergency medicine. More hospital staff than prehospital staff have permanent contracts linked to the department where they work. More hospital physicians are specialized in internal medicine than in family and community medicine. The opinion that emergency services are inadequately staffed was widespread. Most respondents believed that patient transport is good or adequate. However, respondents working in prehospital services expressed a lower opinion of transport. Great difficulty in combining work with family (life achieving work-life balance) was expressed by 13.5% overall, and more often by hospital staff. Some type of aggression was experienced by 88.2%; 60% reported the event to superiors. Nurses reported aggression more often than physicians. A police report was filed by 10.1%. Emergency medicine working conditions can be improved in Catalonia according to members of SoCMUE. Relations between groups of professionals are not optimum in some aspects.

  8. International survey on the management of Chiari 1 malformation and syringomyelia: evolving worldwide opinions.

    Science.gov (United States)

    Singhal, Ash; Cheong, Alexander; Steinbok, Paul

    2018-03-12

    In 2003, pediatric neurosurgeons were surveyed under the auspices of the education committee of the International Society for Pediatric Neurosurgery (ISPN) to determine prevailing opinions regarding the management of Chiari I malformation (C1M) with and without associated syringomyelia. In the ensuing years, there has been further information from multiple C1M studies, with regards to indications, success rates of different surgical interventions, and complications. The purpose of this study was to re-evaluate current opinions and practices in pediatric C1M. Pediatric neurosurgeons worldwide were surveyed, using an e-mail list provided by the ISPN communication committee chairperson. Respondents were given scenarios similar to the 2003 C1M survey in order to determine opinions regarding whether to surgically intervene, and if so, with which operations. Of 300 surveys electronically distributed, 122 responses were received (40.6% response rate)-an improvement over the 30.8% response rate in 2003. Pediatric neurosurgeons from 34 different countries responded. There was broad consensus that non-operative management is appropriate in asymptomatic C1M (> 90%) as well as asymptomatic C1M with a small syrinx (> 65%). With a large syrinx, a majority (almost 80%) recommended surgical intervention. Scoliotic patients with CIM were generally offered surgery only when there was a large syrinx. There has been a shift in the surgical management over the past decade, with a bone-only decompression now being offered more commonly. There remains, however, great variability in the operation offered. This survey, with a relatively strong response rate, and with broad geographic representation, summarizes current worldwide expert opinion regarding management of pediatric C1M. Asymptomatic C1M and C1M with a small syrinx are generally managed non-operatively. When an operation is indicated, there has been a shift towards less invasive surgical approaches.

  9. The Development of the STEM Career Interest Survey (STEM-CIS)

    Science.gov (United States)

    Kier, Meredith W.; Blanchard, Margaret R.; Osborne, Jason W.; Albert, Jennifer L.

    2014-06-01

    Internationally, efforts to increase student interest in science, technology, engineering, and mathematics (STEM) careers have been on the rise. It is often the goal of such efforts that increased interest in STEM careers should stimulate economic growth and enhance innovation. Scientific and educational organizations recommend that efforts to interest students in STEM majors and careers begin at the middle school level, a time when students are developing their own interests and recognizing their academic strengths. These factors have led scholars to call for instruments that effectively measure interest in STEM classes and careers, particularly for middle school students. In response, we leveraged the social cognitive career theory to develop a survey with subscales in science, technology, engineering, and mathematics. In this manuscript, we detail the six stages of development of the STEM Career Interest Survey. To investigate the instrument's reliability and psychometric properties, we administered this 44-item survey to over 1,000 middle school students (grades 6-8) who primarily were in rural, high-poverty districts in the southeastern USA. Confirmatory factor analyses indicate that the STEM-CIS is a strong, single factor instrument and also has four strong, discipline-specific subscales, which allow for the science, technology, engineering, and mathematics subscales to be administered separately or in combination. This instrument should prove helpful in research, evaluation, and professional development to measure STEM career interest in secondary level students.

  10. What do Americans think about public transit? A review of U.S. public opinion polling survey questions.

    Science.gov (United States)

    2015-07-01

    This seed grant research project compiled a set of 56 US public opinion polls that asked respondents their opinions about public : transit. The first and primary goal of the project was to assemble a large set of transit-related survey question...

  11. Opinion survey among residents in the vicinity of wind farms, elected representatives, and general public. Synthesis of results

    International Nuclear Information System (INIS)

    Fourquet, Jerome; Gariazzo, Marie; Merceron, Adeline

    2016-09-01

    This document presents results of a survey comprising a qualitative survey among residents at the vicinity of wind farms, a quantitative survey among the same kind of residents and among a sample representing the French population older than 18, and a qualitative survey among elected representatives of local communities. Graphs illustrate results in terms of opinion on wind energies, of relationship between information and confidence in a wind farm project. Three sets of residents living everyday at the vicinity of wind farms are synthesised in terms of opinion: the convinced ones, the unconcerned ones, and the upset ones. The opinions in terms of impacts (income for local communities and for farmers, the proof of a commitment for a virtuous ecological policy, a way to impulse a dynamics, or local curiosity) are also assessed. The main levers for a higher acceptance of wind farms are identified

  12. A survey on the public opinion regarding nuclear power and energy issues in Fukui prefecture

    International Nuclear Information System (INIS)

    Kosugi, Motoko; Tsuchiya, Tomoko

    2007-01-01

    To 2000 people who were randomly sampled from the basic register of residents in Fukui prefecture, we conducted a questionnaire survey asking their interest in, knowledge of and attitude toward nuclear power, to analyze which perceptions and opinions they had and factors influencing them. The ratios of respondents in Fukui prefecture who think nuclear power is safe, necessary, and should be developed more, are higher than those of surveyed residents who live in other regions where nuclear power plants had been in operation. Differences in gender and age are nearly the same as those found in the nation-wide surveys has shown. The respondents in 'Tsuruga' region, one of the centers of nuclear power research and development, are more acceptive and affirmative to the nuclear power than those in other regions, although they have less knowledge and credibility for nuclear power safety measures, such as regulation and monitoring by government, countermeasure of earthquake, training of workers and so on. We analyzed the perception of risk and the sense of security for nuclear power, and the opinions for necessity and development of nuclear power, using a regression model. According to the estimated 'Tsuruga' model, risk perception of Tsuruga respondents does not affect their opinion if nuclear power should be developed. No influence of the risk perception on their opinion for nuclear power suggest a possibility that residents have strong trust in nuclear power technology and electric power companies based on their long term experience. (author)

  13. An online survey of chiropractors' opinions of continuing education

    Directory of Open Access Journals (Sweden)

    Smith Dean L

    2005-10-01

    Full Text Available Abstract Background Continuing Education (CE for chiropractors is mandatory for licensure in most North American jurisdictions. Numerous chiropractic colleges have begun collaborating with universities to offer master's degree programs. Distance education master's degree programs may be desirable to allow full-time practicing doctors to further their post-graduate education. The present survey sought to answer three questions. First, what is the level of satisfaction of chiropractors with their continuing education? Second, what is the level of interest of chiropractors in online master's degree programs? Lastly, what is the response rate of chiropractors to an online survey? Methods An online survey consisting of 22 multiple choice questions was e-mailed to 1000 chiropractors randomly selected from the mailing list of an online chiropractic newsletter. Upon completion of the questionnaire, participants' answers were saved on a secure site. Data analysis included evaluation of the demographic characteristics of the respondents, their opinions of and patterns of taking CE including online education, preferred learning formats, and their interest in proposed online master's degree programs. A survey response rate was determined. Results Nearly 86% of respondents felt their previously completed CE courses were either somewhat or extremely satisfactory. Over ninety percent of respondents who had completed online or distance CE coursesfound them to be somewhat or extremelysatisfactory. Almost half the respondents indicated that they most preferred online distance learning, while 34.08% most preferred face-to-face interaction. Fifty-three percent of respondents indicated an interest in starting a master's degree program; however 70.46% of respondents were interested in an online master's degree program that would offer CE credit. A response rate of 35.8% was obtained. Conclusion Satisfaction among chiropractors with CE programs is high. The notion of

  14. Gathering Opinions on Depression Information Needs and Preferences: Samples and Opinions in Clinic Versus Web-Based Surveys.

    Science.gov (United States)

    Bernstein, Matthew T; Walker, John R; Sexton, Kathryn A; Katz, Alan; Beatie, Brooke E

    2017-04-24

    There has been limited research on the information needs and preferences of the public concerning treatment for depression. Very little research is available comparing samples and opinions when recruitment for surveys is done over the Web as opposed to a personal invitation to complete a paper survey. This study aimed to (1) to explore information needs and preferences among members of the public and (2) compare Clinic and Web samples on sample characteristics and survey findings. Web survey participants were recruited with a notice on three self-help association websites (N=280). Clinic survey participants were recruited by a research assistant in the waiting rooms of a family medicine clinic and a walk-in medical clinic (N=238) and completed a paper version of the survey. The Clinic and Web samples were similar in age (39.0 years, SD 13.9 vs 40.2 years, SD 12.5, respectively), education, and proportion in full time employment. The Clinic sample was more diverse in demographic characteristics and closer to the demographic characteristics of the region (Winnipeg, Canada) with a higher proportion of males (102/238 [42.9%] vs 45/280 [16.1%]) and nonwhites (Aboriginal, Asian, and black) (69/238 [29.0%] vs 39/280 [13.9%]). The Web sample reported a higher level of emotional distress and had more previous psychological (224/280 [80.0%] vs 83/238 [34.9%]) and pharmacological (202/280 [72.1%] vs 57/238 [23.9%]) treatment. In terms of opinions, most respondents in both settings saw information on a wide range of topics around depression treatment as very important including information about treatment choices, effectiveness of treatment, how long it takes treatment to work, how long treatment continues, what happens when treatment stops, advantages and disadvantages of treatments, and potential side effects. Females, respondents with a white background, and those who had received or felt they would have benefited from therapy in the past saw more information topics as very

  15. Public opinion survey 'Nuclear energy - the present and the future'

    International Nuclear Information System (INIS)

    Matani, R.; Lebegner, J.; Jurkovi, I.-A.; Prah, M.

    2000-01-01

    As a part of Croatian Nuclear Society Young Generation Network efforts in improving relations with the general public, a survey on nuclear energy issues among a student population (18-22 years old) has been planned. The survey, although somewhat modified, is based on a similar one that has been conducted at high schools as a part of organized educational program by the Museum of Technical Sciences and Hrvatska Elektroprivreda. Preliminary results show a positive altitude among the student population when it comes to nuclear power plants. As it can be seen from the obtained data (preliminary analysis), this opinion is mostly built on student awareness of nuclear power plants as a clean energy source. (authors)

  16. [Medical students and psychiatry. A survey of students' opinion].

    Science.gov (United States)

    Giberti, F; Corsini, G; Rovida, S

    1994-06-01

    In the last years research on the didactics of Psychiatry and opinions of medical students on Psychiatry has gained great interest. The authors think that this research could be useful for the improvement of didactics, for better understanding the meanings of professional choice, the identity of psychiatrist and their relationship with colleagues in other medical field. The goal of this research work was a preliminary survey of Genoese University Medical Student's opinions about psychiatry didactics, and choice of specialization. A questionnaire was submitted to all the students who passed Clinical Psychiatry examination in the period from November 1987 to December 1988. The students were divided in two randomized groups: the first group of students (224) was submitted to the questionnaire immediately after Clinical Psychiatry examination; while to the second group of students (66) the questionnaire was mailed. The aim of the questions was to assess the student's opinions on psychiatry, psychoanalysis, psychotherapy, the career they wanted to take up, and the difficulties of studying psychiatry: 69% of the students of the first group and 42% of the students of the second group answered the questionnaire. Female students answered that they preferred psychiatric specialization more than their male colleagues did, but the difference has no statistical importance. In most cases, the students who answered that they have taken into account psychiatry as a choice of specialisation, are more interested in medical specialties (primary care, etc.) than in surgical specialties. Most of the medical students declare some emotional troubles (anxiety, sleeplessness, problem in social relations).(ABSTRACT TRUNCATED AT 250 WORDS)

  17. Food irradiation: Public opinion surveys

    International Nuclear Information System (INIS)

    Kerr, S.D.

    1987-01-01

    The Canadian government are discussing the legislation, regulations and practical protocol necessary for the commercialization of food irradiation. Food industry marketing, public relations and media expertise will be needed to successfully introduce this new processing choice to retailers and consumers. Consumer research to date including consumer opinion studies and market trials conducted in the Netherlands, United States, South Africa and Canada will be explored for signposts to successful approaches to the introduction of irradiated foods to retailers and consumers. Research has indicated that the terms used to describe irradiation and information designed to reduce consumer fears will be important marketing tools. Marketers will be challenged to promote old foods, which look the same to consumers, in a new light. Simple like or dislike or intention to buy surveys will not be effective tools. Consumer fears must be identified and effectively handled to support a receptive climate for irradiated food products. A cooperative government, industry, health professional, consumer association and retailer effort will be necessary for the successful introduction of irradiated foods into the marketplace. Grocery Products Manufacturers of Canada is a national trade association of more than 150 major companies engaged in the manufacture of food, non-alcoholic beverages and array of other national-brand consumer items sold through retail outlets

  18. Adaptation and Validation of the Brief Sexual Opinion Survey (SOS) in a Colombian Sample and Factorial Equivalence with the Spanish Version

    Science.gov (United States)

    Sierra, Juan Carlos; Soler, Franklin

    2016-01-01

    Attitudes toward sexuality are a key variable for sexual health. It is really important for psychology and education to have adapted and validated questionnaires to evaluate these attitudes. Therefore, the objective of this research was to adapt, validate and calculate the equivalence of the Colombia Sexual Opinion Survey as compared to the same survey from Spain. To this end, a total of eight experts were consulted and 1,167 subjects from Colombia and Spain answered the Sexual Opinion Survey, the Sexual Assertiveness Scale, the Massachusetts General Hospital-Sexual Functioning Questionnaire, and the Sexuality Scale. The evaluation was conducted by online and the results show adequate qualitative and quantitative properties of the items, with adequate reliability and external validity and compliance with the strong invariance between the two countries. Consequently, the Colombia Sexual Opinion Survey is a valid and reliable scale and its scores can be compared with the ones from the Spain survey, with minimum bias. PMID:27627114

  19. Scientific Opinion on erucic acid in feed and food

    DEFF Research Database (Denmark)

    Petersen, Annette

    Erucic acid is the trivial name of the fatty acid cis-13-docosenoic acid and occurs at high concentrations mainly in the seeds of species of the Brassicaceae (e.g. rape seed or mustard seed). The European Commission requested EFSA to deliver a scientific opinion on the risks for animal and human...

  20. Scientific opinion: Erucic acid in feed and food

    NARCIS (Netherlands)

    Hoogenboom, L.A.P.

    2016-01-01

    Erucic acid is the trivial name of the fatty acid cis-13-docosenoic acid and occurs at high concentrations mainly in the seeds of species of the Brassicaceae (e.g. rape seed or mustard seed). The European Commission requested EFSA to deliver a scientific opinion on the risks for animal and human

  1. DATA COLLECTION, QUALITY ASSURANCE, AND ANALYSIS PLAN FOR THE 2008/2009 HYDROGEN AND FUEL CELLS KNOWLEDGE AND OPINIONS SURVEYS

    Energy Technology Data Exchange (ETDEWEB)

    Schmoyer, Richard L [ORNL; Truett, Lorena Faith [ORNL; Diegel, Susan W [ORNL

    2008-09-01

    The 2008/2009 Knowledge and Opinions Survey, conducted for the Department of Energy's Hydrogen Program will measure the levels of awareness and understanding of hydrogen and fuel cell technologies within five target populations: (1) the general public, (2) students, (3) personnel in state and local governments, (4) potential end users of hydrogen fuel and fuel cell technologies in business and industry, and (5) safety and code officials. The ultimate goal of the surveys is a statistically valid, nationally based assessment. Distinct information collections are required for each of the target populations. Each instrument for assessing baseline knowledge is targeted to the corresponding population group. While many questions are identical across all populations, some questions are unique to each respondent group. The biggest data quality limitation of the hydrogen survey data (at least of the general public and student components) will be nonresponse bias. To ensure as high a response rate as possible, various measures will be taken to minimize nonresponse, including automated callbacks, cycling callbacks throughout the weekdays, and availability of Spanish speaking interviewers. Statistical adjustments (i.e., sampling weights) will also be used to account for nonresponse and noncoverage. The primary objective of the data analysis is to estimate the proportions of target population individuals who would respond to the questions in the various possible ways. Data analysis will incorporate necessary adjustments for the sampling design and sampling weights (i.e., probability sampling). Otherwise, however, the analysis will involve standard estimates of proportions of the interviewees responding in various ways to the questions. Sample-weight-adjusted contingency table chi-square tests will also be computed to identify differences between demographic groups The first round of Knowledge and Opinions Surveys was conducted in 2004. Analysis of these surveys produced a

  2. Longitudinal survey of public opinion toward nuclear power generation. The result of a survey conducted one year after the Mihama Unit 3 accident

    International Nuclear Information System (INIS)

    Kitada, Atsuko

    2006-01-01

    As part of an ongoing public opinion survey, regarding nuclear power generation, which started in 1993, a survey was carried out in the Kansai area in 2005, one year and two months after the accident at Unit 3 of the Mihama Nuclear Power Plant. It was found that people's memory about the accident decreased drastically. All questionnaire items that indicated a negative change two months after the accident returned to pre-accident levels. It was confirmed that the accident had only a temporary influence on public opinions. Moreover, the study also revealed a decrease in the public distrust of unclear power. It seems that people's evaluation of and attitude toward nuclear power generation have become slightly more positive since 2002. (author)

  3. Using expert opinion surveys to rank threats to endangered species: a case study with sea turtles.

    Science.gov (United States)

    Donlan, C Josh; Wingfield, Dana K; Crowder, Larry B; Wilcox, Chris

    2010-12-01

    Little is known about how specific anthropogenic hazards affect the biology of organisms. Quantifying the effect of regional hazards is particularly challenging for species such as sea turtles because they are migratory, difficult to study, long lived, and face multiple anthropogenic threats. Expert elicitation, a technique used to synthesize opinions of experts while assessing uncertainty around those views, has been in use for several decades in the social science and risk assessment sectors. We conducted an internet-based survey to quantify expert opinion on the relative magnitude of anthropogenic hazards to sea turtle populations at the regional level. Fisheries bycatch and coastal development were most often ranked as the top hazards to sea turtle species in a geographic region. Nest predation and direct take followed as the second and third greatest threats, respectively. Survey results suggest most experts believe sea turtles are threatened by multiple factors, including substantial at-sea threats such as fisheries bycatch. Resources invested by the sea turtle community, however, appear biased toward terrestrial-based impacts. Results from the survey are useful for conservation planning because they provide estimates of relative impacts of hazards on sea turtles and a measure of consensus on the magnitude of those impacts among researchers and practitioners. Our survey results also revealed patterns of expert bias, which we controlled for in our analysis. Respondents with no experience with respect to a sea turtle species tended to rank hazards affecting that sea turtle species higher than respondents with experience. A more-striking pattern was with hazard-based expertise: the more experience a respondent had with a specific hazard, the higher the respondent scored the impact of that hazard on sea turtle populations. Bias-controlled expert opinion surveys focused on threatened species and their hazards can help guide and expedite species recovery plans.

  4. Teachers' Opinion Survey on the Use of ICT Tools to Support Attendance-Based Teaching

    Science.gov (United States)

    Castro Sanchez, Jose Juan; Aleman, Elena Chirino

    2011-01-01

    The present paper reports on the results obtained from a teachers' opinion survey on the use of ICT tools to support of attendance-based teaching. In order to carry out this study, it was necessary to design a questionnaire to collect data among all in-service teachers with access to the university virtual campus. The findings show that…

  5. IRSN 2014 opinion survey - The perception of risks and security by the French population. Global results

    International Nuclear Information System (INIS)

    El Jammal, Marie-Helene; Mur, Emmanuelle; Rollinger, Francois; Schuler, Matthieu; Tchernia, Jean-Francois

    2014-06-01

    A first and synthetic part of this report comments the most remarkable results of the opinion survey. It first addresses results related to a context of economic crisis (importance of the economic crisis and unemployment as major concerns for French people, environmental concerns) and then analyzes the different aspects of the nuclear risk, from the accident to nuclear safety: strong fears of a nuclear accident, Fukushima and Chernobyl are immediately present in people's mind, concerns about nuclear are also related to the environment and health, the actual benefit of nuclear is an economic one, nuclear safety is a major challenge on which French people doubt, French people wish a citizen look on nuclear safety, the opinion of French people on nuclear worsened in 2013. Then, this report, illustrated by several graphs, presents and discusses the results of an annual opinion survey on the present concerns of French people (in the present society, for the environment, and as far as science is concerned), the opinion of French people on expertise (about who must control a risky installation, about the role and image of scientific experts, about the diffusion and sharing of scientific expertise, and about the perception of pluralistic structures), on the attitude of French people in front of 33 risk situations (risks to which French people feel exposed to, confidence of French people in authorities to protect them, the truth of information on hazards, the hierarchy of 33 situations according to 3 aspects and their relationship with installation acceptability). The fourth part addresses more particularly the nuclear sector: expectations in terms of nuclear risk management, fear of a serious accident, benefits and drawbacks of nuclear energy, skill and credibility of interveners. Graphs notably present the evolution of opinions with respect to last year or over the past years

  6. The "Public Opinion Survey of Human Attributes-Stuttering" (POSHA-S): Summary Framework and Empirical Comparisons

    Science.gov (United States)

    St. Louis, Kenneth O.

    2011-01-01

    Purpose: The "Public Opinion Survey of Human Attributes-Stuttering" ("POSHA-S") was developed to make available worldwide a standard measure of public attitudes toward stuttering that is practical, reliable, valid, and translatable. Mean data from past field studies as comparisons for interpretation of "POSHA-S" results are reported. Method: Means…

  7. Public opinion survey on the relationship between society and nuclear energy

    International Nuclear Information System (INIS)

    Shinoda, Yoshihiko; Yamano, Naoki; Torii, Hiroyuki

    2008-01-01

    The social research group of the 21st century COE program 'Innovative Nuclear Energy Systems for Sustainable Development of the World' has studied under the theme coevolution of nuclear technology and society. As part of this study, this group conducted a questionnaire survey of 2,500 adults (collection rate of 22.0%; 551 replies) who live in the Tokyo metropolitan area. The purpose of this survey asking opinion about the relationship between attitude toward nuclear technology utilization and social awareness is to determine their request, exception and concern about nuclear technology utilization. The survey reveals that the differences of attitudes towards nuclear technology utilization can be explained in terms of differences of general views on the society, such as the directionality of social progress. Thus, it is necessary to argue with citizens about the strategy on nuclear technology utilization from the viewpoint of the directionality of the future society. The social decision-making process on nuclear technology utilization has to be renovated through dialogue among citizens as the partner taking on the achievement and contribution toward the directionality of the future society. (author)

  8. Travel opinion leaders and seekers

    DEFF Research Database (Denmark)

    Yoo, Kyung-Hyan; Gretzel, Ulrike; Zach, Florian

    2011-01-01

    While opinion leadership has been recognized as important in tourism, there has been very little empirical research investigating the phenomenon. Given new developments in social media technologies, it is especially important to understand whether travel opinion leadership and seeking are drivers...... of specific social media perceptions and behaviours. Based on an online survey of US online travellers, this paper seeks to identify travel opinion leaders and seekers and their characteristics. Further, the research conducted investigated linkages between travel opinion leadership/seeking and travel social...... media use. The findings suggest that travel opinion leadership and seeking are distinct but connected. Both opinion leaders and seekers are technology savvy, young, educated, involved in travel planning and engaged in social media use for travel. What distinguishes opinion leaders is their greater...

  9. Survey of Professional Opinion on Critical Transition Skills for Adolescents and Young Adults Who Are Deaf.

    Science.gov (United States)

    Bullis, Michael; Reiman, John W.

    1989-01-01

    Surveyed national sample of 307 professionals in relevant fields to obtain professional opinion on critical competencies necessary for deaf individuals to live and work successfully in the community. Findings identified 12 critical skills in employment and 10 critical skills in independent living. (Author/NB)

  10. A Survey of Key Technology of Network Public Opinion Analysis

    Directory of Open Access Journals (Sweden)

    Li Su Ying

    2016-01-01

    Full Text Available The internet has become an important base for internet users to make comments because of its interactivity and fast dissemination. The outbreak of internet public opinion has become a major risk for network information security. Domestic and foreign researchers had carried out extensive and in-depth study on public opinion. Fruitful results have achieved in the basic theory research and emergency handling and other aspects of public opinion. But research on the public opinion in China is still in the initial stage, the key technology of the public opinion analysis is still as a starting point for in-depth study and discussion.

  11. The Asilomar Survey: Stakeholders? Opinions on Ethical Issues Related to Brain-Computer Interfacing

    OpenAIRE

    Nijboer, Femke; Clausen, Jens; Allison, Brendan Z.; Haselager, Pim

    2011-01-01

    Brain-Computer Interface (BCI) research and (future) applications raise important ethical issues that need to be addressed to promote societal acceptance and adequate policies. Here we report on a survey we conducted among 145 BCI researchers at the 4th International BCI conference, which took place in May–June 2010 in Asilomar, California. We assessed respondents’ opinions about a number of topics. First, we investigated preferences for terminology and definitions relating to BCIs. Second, w...

  12. Public opinion about condoms for HIV and STD prevention: a Midwestern state telephone survey.

    Science.gov (United States)

    Yarber, William L; Milhausen, Robin R; Crosby, Richard A; Torabi, Mohammad R

    2005-09-01

    Public opinion is important in determining condom and condom education policies in public high schools. A random telephone survey of 517 Indiana residents was conducted from July through October 2003 to assess public opinion about education on correct condom use for HIV and STD prevention; condom availability in Indiana public high schools; and issues related to condom use, effectiveness and promotion. Data were analyzed using bivariate and linear regression techniques. A majority of respondents strongly or somewhat agreed that instruction on correct condom use for HIV and STD prevention should be provided in public high schools (77%), classroom instruction should include condoms (71%), only medically accurate information about condoms should being given (94%) and the federal government should promote condoms (70%). Fewer than half (48%) strongly or somewhat agreed that condoms should be made available to teenagers in public high schools without parental permission. Nearly all (92%) considered condoms at least somewhat effective in preventing HIV and other STDs. Non-Republican party affiliation, younger age and condom use within the previous five years were each significantly associated with having positive opinions on many of the condom-related statements. Public opinion appears to support the provision of correct condom use information in Indiana public schools. Schools should consider providing only medically accurate information about condoms and including condoms in instruction so students can see and touch them.

  13. Etiological explanation, treatability and preventability of childhood autism: a survey of Nigerian healthcare workers' opinion

    Directory of Open Access Journals (Sweden)

    Okonkwo Kevin O

    2009-02-01

    workers in subscribing to treatability of childhood autism, while working experience of less than 6 years among the healthcare workers significantly influenced the opinion of the healthcare workers in admitting to believing in the preventability of childhood autism. Conclusion In designing policies and programs to change negative opinions or beliefs of healthcare workers about childhood autism, there is a need for baseline information such as this survey. Changing the negative opinions or beliefs of the healthcare workers about childhood autism should encourage appropriate help-seeking behavior among parents of children with ASD who may be seeking advice or information from the healthcare workers. This would encourage early interventions, which are essential to prognosis of childhood autism.

  14. National 2010 survey on the awareness and opinion of the French about geological carbon storage

    International Nuclear Information System (INIS)

    Ha-Duong, Minh; Arnoux, Stephanie; Chaabane, Naceur; Mardon, Gilles; Nadai, Alain; Neri O'Neill, Rebeca

    2011-01-01

    This report presents the results of the 2010 CIRED / TNS Sofres public opinion survey about geological storage of CO 2 in France. The first survey, in April 2007, demonstrated a broad consensus for action against climate change. Three years later in March 2010, even a wide support for action remains, the public opinion was marked from the Copenhagen fiasco and the 'climate-gate'. More generally, in a context of global economic crisis, compared to 2007 the economy/environment balance moves back in 2010 towards the former term. Thus, 62% of the French answered that there is a need to act against climate change, that is 17 points less than three years ago. And 67% estimated that 'the priority must go to the protection of the environment' instead of the economy, that is 11 points less. The 2007 survey suggested that 6% of the respondents were able to define correctly geological storage of CO 2 . The approval rate was 59% at first, but fell to 38% after reading about the risks of the technology. Three years later, the context included emerging CCS projects in France, a (failed) carbon tax proposal and sustained debates on climate change. While CCS has never been a hot topic in the media, it moved from being inexistent to a few specific papers each semesters in important newspapers and some TV / radio air-time. Between 2007 and 2010 the notoriety of CCS increased in France, but the rates of approval mostly stagnated: 57% at first, falling to 37% after the reading on risks. The expression 'stockage geologique du CO 2 ' is now recognized by one third of the French, and about 17% can provide an exact definition. There remain an ambiguity with sequestration in forests, and the mental image of storing CO 2 in underground caves or vessels remains widespread. Our study shows a statistically significant positive correlation between more information and a favorable opinion towards geological sequestration. The opinion of respondents is more stable

  15. Public Opinion Survey - Energy, The Present and The Future, 2015

    International Nuclear Information System (INIS)

    Trontl, K.; Pevec, D.; Matijevic, M.; Jecmenica, R.; Duckic, P.; Lebegner, J.

    2016-01-01

    During the year 2015 the Department of Applied Physics of the Faculty of Electrical Engineering and Computing, University of Zagreb conducted a public opinion survey entitled 'Energy - The Present and the Future' among student population of 1115 individuals. The tested population consisted of the University of Zagreb six faculties' students: the Faculty of Electrical Engineering and Computing, the Faculty of Food Technology and Biotechnology, the Faculty of Chemical Engineering and Technology, the Faculty of Mining, Geology and Petroleum Engineering, the Faculty of Science, and the Faculty of Humanities and Social Sciences. The questions in the survey covered several different energy issues, including the present and the future energy resources, the acceptability of different fuel type power plants, the environmental protection and global warming, the radioactivity, the radioactive waste issues, reliable information sources, and position of participants towards climate change issues, as well as European Union and Croatian goals set for the year 2020. The basic results of survey analysis for nuclear oriented questions, as well as the comparison of results of the current survey with the results of the similar surveys conducted in the academic years 2007/08, and 2012/2013, are reported in this paper. Participants generally express high level of formal environmental awareness. However, their choices and attitudes are in a contradiction to claimed eco-orientation, as well as to the scientific facts. The discrepancies are particularly noticeable in parts of the survey dealing with the nuclear energy and the nuclear power plants. The participants are also demonstrating lack of knowledge on nuclear issues especially regarding radioactive waste management, as well as economics and operational safety of nuclear power plants. (author).

  16. Oral contraception and menstrual bleeding during treatment of venous thromboembolism: Expert opinion versus current practice: Combined results of a systematic review, expert panel opinion and an international survey

    NARCIS (Netherlands)

    Klok, F. A.; Schreiber, K.; Stach, K.; Ageno, W.; Middeldorp, S.; Eichinger, S.; Delluc, A.; Blondon, M.; Ay, C.

    2017-01-01

    The optimal management of oral contraception and menstrual bleeding during treatment of venous thromboembolism (VTE) is largely unknown. We aimed to elicit expert opinion and compare that to current practice as assessed by a world-wide international web-based survey among physicians. 10

  17. A survey of parental opinions on corporal punishment in schools.

    Science.gov (United States)

    Kelly, P C; Weir, M R; Fearnow, R G

    1985-06-01

    Forty-three states permit corporal punishment in schools. This practice continues despite the universal opposition of professional organizations, including the American Academy of Pediatrics. This study determines parental attitudes concerning the use of physical punishment in schools. The surveyed sample is drawn from parents of military dependents who brought their children to this clinic for routine physical examinations. One hundred and twenty-nine of 132 questionnaires were returned for a 98% response rate. Fifty-one percent of the parents supported the use of corporal punishment in schools, 37% disagreed (77% of these strongly), 11% had no opinion, and 1% did not respond to the question. Analysis of the responses displayed a relationship between parental attitudes on the use of corporal punishment and opinion of the positive effects of physical punishment on children's behavior (p less than 0.0001). No relationship was found between position on corporal punishment and the respondent (mother, father, or both), the age of parents, the military rank of the sponsor (the individual whose military service makes the child eligible for military medical care, i.e., father, mother, guardian, etc.), the sex of the children, the marital status of the parents, or the schools attended by the children (public or private). Thirty-four percent of parents believed corporal punishment would improve behavior, and 20% of parents felt that physical punishment would improve their child's academic performance.

  18. The Asilomar Survey: Stakeholders' Opinions on Ethical Issues Related to Brain-Computer Interfacing.

    Science.gov (United States)

    Nijboer, Femke; Clausen, Jens; Allison, Brendan Z; Haselager, Pim

    2013-01-01

    Brain-Computer Interface (BCI) research and (future) applications raise important ethical issues that need to be addressed to promote societal acceptance and adequate policies. Here we report on a survey we conducted among 145 BCI researchers at the 4 th International BCI conference, which took place in May-June 2010 in Asilomar, California. We assessed respondents' opinions about a number of topics. First, we investigated preferences for terminology and definitions relating to BCIs. Second, we assessed respondents' expectations on the marketability of different BCI applications (BCIs for healthy people, BCIs for assistive technology, BCIs-controlled neuroprostheses and BCIs as therapy tools). Third, we investigated opinions about ethical issues related to BCI research for the development of assistive technology: informed consent process with locked-in patients, risk-benefit analyses, team responsibility, consequences of BCI on patients' and families' lives, liability and personal identity and interaction with the media. Finally, we asked respondents which issues are urgent in BCI research.

  19. Public Opinion Survey - Energy - The Present and the Future - 2009/10

    International Nuclear Information System (INIS)

    Trontl, K.; Jecmenica, R.; Pevec, D.

    2010-01-01

    During the academic year 2009/10 the Department of Applied Physics of the Faculty of Electrical Engineering and Computing conducted a public opinion survey entitled 'Energy - The Present and the Future' among student population of 622 individuals age 18-20 (413 male students, 202 female students, and 7 students without the answer on gender question). The tested population consisted of the University of Zagreb four faculties' students: the Faculty of Electrical Engineering and Computing, the Faculty of Food Technology and Biotechnology, the Faculty of Chemical Engineering and Technology, the Faculty of Civil Engineering. The questions in the survey covered several different energy issues, including the present and the future energy resources, the acceptability of different fuel type power plants, the environmental protection and global warming, the radioactivity, the waste issues, as well as reliable information sources. The basic results of survey analysis for nuclear oriented questions, as well as the comparison of results of the current survey with the results of the similar survey conducted in the academic year 2007/08, are reported in this paper. Participants generally express high level of formal environmental awareness. However, their choices and attitudes are in a contradiction to claimed eco-orientation, as well as to the scientific facts. The discrepancies are particularly noticeable in parts of the survey dealing with the nuclear energy and the nuclear power plants. The participants are also demonstrating lack of knowledge on nuclear issues especially regarding radioactive waste management, as well as economics and operational safety of nuclear power plants.(author).

  20. [Response rates in three opinion surveys performed through online questionnaires in the health setting].

    Science.gov (United States)

    Aerny Perreten, Nicole; Domínguez-Berjón, Ma Felicitas; Astray Mochales, Jenaro; Esteban-Vasallo, María D; Blanco Ancos, Luis Miguel; Lópaz Pérez, Ma Ángeles

    2012-01-01

    The main advantages of online questionnaires are the speed of data collection and cost savings, but response rates are usually low. This study analyzed response rates and associated factors among health professionals in three opinion surveys in the autonomous region of Madrid. The participants, length of the questionnaire and topic differed among the three surveys. The surveys were conducted by using paid Internet software. The institutional e-mail addresses of distinct groups of health professionals were used. Response rates were highest in hospitals (up to 63%) and administrative services and were lowest in primary care (less than 33%). The differences in response rates were analyzed in primary care professionals according to age, sex and professional category and only the association with age was statistically significant. None of the surveys achieved a response rate of 60%. Differences were observed according to workplace, patterns of Internet usage, and interest in the subject. Copyright © 2011 SESPAS. Published by Elsevier Espana. All rights reserved.

  1. Opinions on cell phone use on airplanes, congestion, and telecommuting — from the 2006 and 2007 Omnibus Household Survey

    Science.gov (United States)

    2008-07-01

    The annual Omnibus Household Survey (OHS), administered by the U.S. Department of Transportations Bureau of Transportation Statistics (BTS), asks respondents about their weekly travel habits, journey to work, opinions about the transportation syst...

  2. Public Opinion Survey - Energy - The Present and the Future - 2012/2013

    International Nuclear Information System (INIS)

    Trontl, Kresimir; Pevec, Dubravko; Matijevic, Mario; Jecmenica, Radomir; Lebegner, Josip

    2014-01-01

    During the academic year 2012/13 the Department of Applied Physics of the Faculty of Electrical Engineering and Computing, University of Zagreb conducted a public opinion survey entitled 'Energy- The Present and the Future' among student population of more than 950 individuals. The tested population consisted of the University of Zagreb five faculties' and one polytechnic school's students: the Faculty of Electrical Engineering and Computing, the Faculty of Food Technology and Biotechnology, the Faculty of Chemical Engineering and Technology, the Faculty of Civil Engineering, the Faculty of Science, and the Polytechnic of Zagreb. The questions in the survey covered several different energy issues, including the present and the future energy resources, the acceptability of different fuel type power plants, the environmental protection and global warming, the radioactivity, the waste issues, reliable information sources, and position of participants towards climate change issues, , as well as European Union and Croatian goals set for the year 2020. The basic results of survey analysis for nuclear oriented questions, as well as the comparison of results of the current survey with the results of the similar surveys conducted in the academic years 2007/08 and 2009/2010, are reported in this paper. Participants generally express high level of formal environmental awareness. However, their choices and attitudes are in a contradiction to claimed eco-orientation, as well as to the scientific facts. The discrepancies are particularly noticeable in parts of the survey dealing with the nuclear energy and the nuclear power plants. The participants are also demonstrating lack of knowledge on nuclear issues especially regarding radioactive waste management, as well as economics and operational safety of nuclear power plants. (authors)

  3. Vestibular Assessment and Rehabilitation: Ten-Year Survey Trends of Audiologists' Opinions and Practice.

    Science.gov (United States)

    Nelson, M Dawn; Akin, Faith W; Riska, Kristal M; Andresen, Kimberly; Mondelli, Stephanie Stamps

    2016-02-01

    The past decade has yielded changes in the education and training of audiologists and technological advancements that have become widely available for clinical balance function testing. It is unclear if recent advancements in vestibular instrumentation or the transition to an AuD degree have affected audiologists' vestibular clinical practice or opinions. The purpose of this study was to examine predominant opinions and practices for vestibular assessment (VA) and vestibular rehabilitation (VR) over the past decade and between master's- and AuD-level audiologists. A 31-question survey was administered to audiologists via U.S. mail in 2003 (N = 7,500) and electronically in 2014 (N = 9,984) with a response rate of 12% and 10%, respectively. There was an increase in the number of audiologists providing vestibular services in the past decade. Most respondents agreed that audiologists were the most qualified professionals to conduct VA. Less than half of the surveyed audiologists felt that graduate training was adequate for VA. AuD-level audiologists were more satisfied with graduate training and felt more comfortable performing VA compared to master's-level audiologists. Few respondents agreed that audiologists were the most qualified professionals to conduct VR or that graduate training prepared them to conduct VR. The basic vestibular test battery was unchanged across surveys and included: calorics, smooth pursuit, saccades, search for spontaneous, positional, gaze and optokinetic nystagmus, Dix-Hallpike, case history, and hearing evaluation. There was a trend toward greater use of air (versus water) calorics, videonystagmography (versus electronystagmography), and additional tests of vestibular and balance function. VA is a growing specialty area in the field of audiology. Better training opportunities are needed to increase audiologists' knowledge and skills for providing vestibular services. The basic tests performed during VA have remained relatively unchanged

  4. Perspectives of tax reforms in Croatia: expert opinion survey

    Directory of Open Access Journals (Sweden)

    Hrvoje Šimović

    2014-12-01

    Full Text Available In order to shape tax reform it is necessary objectively to assess the current stateof-the-art of and of the outlook for the tax system. After having reviewed all previous reforms in the light of the consumption-based (interest-adjusted concept of direct taxation, which was almost systematically implemented in Croatia in 1994, we present the results of a broad expert opinion survey about the Croatian tax system. The most interesting results suggest the maintenance/(reintroduction of different tax incentives and reduced VAT rates, rejection of a flat tax as well as decrease of tax brackets, an increase in alcohol and tobacco duties, the introduction of a financial activities tax, a further shift from income to consumption, a decrease of the tax share in GDP and a belief in the behavioral responsiveness of tax decreases/exemptions, as well as a firm commitment to the principle of equity. The last three economic views/values are important predictors of other tax attitudes.

  5. Surveyed opinion of American trauma surgeons in management of colon injuries.

    Science.gov (United States)

    Eshraghi, N; Mullins, R J; Mayberry, J C; Brand, D M; Crass, R A; Trunkey, D D

    1998-01-01

    Primary repair or resection and anastomosis of colon wounds have been advocated in many recent studies, but the proportion of trauma surgeons accepting these recommendations is unknown. To determine the current preferences of American trauma surgeons for colon injury management. Four hundred forty-nine members of the American Association for the Surgery of Trauma were surveyed regarding their preferred management of eight types of colon wounds among three options: diverting colostomy (DC), primary repair (PR), or resection and anastomosis (RA). The influence of selected patient factors and surgeons' characteristics on the choice of management was also surveyed. Seventy-three percent of surgeons completed the survey. Ninety-eight percent chose PR for at least one type of injury. Thirty percent never selected DC. High-velocity gunshot wound was the only injury for which the majority (54%) would perform DC. More than 55% of the surgeons favored RA when the isolated colon injury was a contusion with possible devascularization, laceration greater than 50% of the diameter, or transection. Surgeons who managed five or fewer colon wounds per year chose DC more frequently (p colon wounds per year. The prevailing opinion of trauma surgeons favors primary repair or resection of colon injuries, including anastomosis of unprepared bowel. Surgeons who manage fewer colon wounds prefer colostomy more frequently.

  6. Results of the 2004 Knowledge and Opinions Surveys for the Baseline Knowledge Assessment of the U.S. Department of Energy Hydrogen Program

    Energy Technology Data Exchange (ETDEWEB)

    Schmoyer, Richard L [ORNL; Truett, Lorena Faith [ORNL; Cooper, Christy [U.S. Department of Energy

    2006-04-01

    The U.S. Department of Energy (DOE) Hydrogen Program focuses on overcoming critical barriers to the widespread use of hydrogen fuel cell technology. The transition to a new, hydrogen-based energy economy requires an educated human infrastructure. With this in mind, the DOE Hydrogen Program conducted statistical surveys to measure and establish baselines for understanding and awareness about hydrogen, fuel cells, and a hydrogen economy. The baseline data will serve as a reference in designing an education program, and it will be used in comparisons with future survey results (2008 and 2011) to measure changes in understanding and awareness. Scientific sampling was used to survey four populations: (1) the general public, ages 18 and over; (2) students, ages 12-17; (3) state and local government officials; and (4) potential large-scale hydrogen users. It was decided that the survey design should include about 1,000 individuals in each of the general public and student categories, about 250 state and local officials, and almost 100 large-scale end users. The survey questions were designed to accomplish specific objectives. Technical questions measured technical understanding and awareness of hydrogen technology. Opinion questions measured attitudes about safety, cost, the environment, and convenience, as well as the likelihood of future applications of hydrogen technology. For most of the questions, "I don't know" or "I have no opinion" were acceptable answers. Questions about information sources assessed how energy technology information is received. The General Public and Student Survey samples were selected by random digit dialing. Potential large-scale end users were selected by random sampling. The State and Local Government Survey was of the entire targeted population of government officials (not a random sample). All four surveys were administered by computer-assisted telephone interviewing (CATI). For each population, the length of the survey was less than

  7. 78 FR 73238 - Currently Approved Information Collection: Comment Request for Customer Satisfaction and Opinion...

    Science.gov (United States)

    2013-12-05

    ... Request for Customer Satisfaction and Opinion Surveys and Focus Group Interviews AGENCY: United States... Treasury, is soliciting comments on the United States Mint customer satisfaction and opinion surveys and.... Abstract: The proposed customer satisfaction and opinion surveys will allow the United States Mint to...

  8. Public Opinion Survey-Energy-The Present and the Future

    International Nuclear Information System (INIS)

    Pejic Bach, M.; Pevec, D.; Bace, M.; Trontl, K.; Jecmenica, R.; Matijevic, M.; Lebegner, J.

    2008-01-01

    During the academic year 2007/08 the Department of Applied Physics of the Faculty of Electrical Engineering and Computing conducted a public opinion survey entitled 'Energy - The Present and the Future' among student population of 1439 individuals age 18-20. The tested population consisted of the University of Zagreb nine faculties' students: the Faculty of Electrical Engineering and Computing - 367 students, the Faculty of Food Technology and Biotechnology - 149 students, the Faculty of Chemical Engineering and Technology - 118 students, the Faculty of Civil Engineering - 102 students, the Faculty of Philosophy - 100 students, the Faculty of Science - 50 students, the Medical School - 217 students, the School of Dental Medicine - 108 students, and the Faculty of Economics and Business - 228 students. The questions in the survey covered several different energy issues, including the present and the future energy resources, the acceptability of different fuel type power plants, the environmental protection and global warming, the radioactivity, the waste issues, as well as reliable information sources. The basic results of survey analysis for nuclear oriented questions are reported in this paper. Although participants expressed high level of formal environmental awareness, their choices and attitudes are in a contradiction to claimed eco-orientation, as well as to the scientific facts. The discrepancies are particularly noticeable in parts of the survey dealing with the nuclear energy and the nuclear power plants. The radioactive waste management, proved to be a potential stumbling-stone for the entire nuclear program. The participants are demonstrating deep lack of knowledge which results in the radioactive waste management becoming the main source of fear from the nuclear technology in general. A very disturbing attitude is a belief that the nuclear energy is non-economic, environmentally unacceptable and operationally unsafe source of energy. Such an attitude

  9. A Survey of First-Year Biology Student Opinions Regarding Live Lectures and Recorded Lectures as Learning Tools

    Science.gov (United States)

    Simcock, D. C.; Chua, W. H.; Hekman, M.; Levin, M. T.; Brown, S.

    2017-01-01

    A cohort of first-year biology students was surveyed regarding their opinions and viewing habits for live and recorded lectures. Most respondents (87%) attended live lectures as a rule (attenders), with 66% attending more than two-thirds of the lectures. In contrast, only 52% accessed recordings and only 13% viewed more than two-thirds of the…

  10. IRSN 2011 opinion survey. The perception of risks and safety by French people. Global results

    International Nuclear Information System (INIS)

    2011-01-01

    Like every year, this report presents and comments the results of an opinion survey on risks, and more particularly on nuclear and radiological risks. The first part addresses the current concerns of French people (the main concerns in the present society and with respect to the environment, how science is considered). The second part addresses the opinion on expertise (who should control a hazardous installation, the role and image of experts, the access to expertise files, the perception of pluralist bodies). The third part examines the reaction of people in front of 33 different hazardous situations (risks to which people feel being exposed, confidence in authorities, confidence in information on hazards, hierarchy of 33 situations and relationship with installation acceptability). The fourth part addresses the nuclear issue (nuclear risk, ability and credibility of nuclear actors, the Chernobyl accident, radioactive wastes, demand of information on the nuclear risk).

  11. PVMapper: Report on the Second Public Opinion Survey

    Energy Technology Data Exchange (ETDEWEB)

    Carlisle, Juliet [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States); Kane, Stephanie [Idaho National Lab. (INL), Idaho Falls, ID (United States); Koehler, Dave [Idaho National Lab. (INL), Idaho Falls, ID (United States); Solan, David [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2013-06-24

    This report has been developed as an integral part of the PVMapper project, funded by the U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy’s SunShot program. The objective of the SunShot program is to reduce the total costs of solar energy systems. The scope of PVMapper is to develop a geographic information system (GIS) based project planning tool to identify optimal utility-scale solar facility sites. The specific objectives of the project are to 1) develop the software on an open-source platform; 2) integrate the appropriate data sets and GIS layers; 3) include a measure of social risk and public acceptance; 4) enable customization of variable weights; 5) provide a free and accessible platform for software download; and 6) provide a sustainability plan to ensure future relevance of the software. When completed, PVMapper is intended to be used by solar developers, Authorities Having Jurisdiction (AHJs), and other interested parties. This project supports SunShot’s objective by reducing the non-hardware balance of system costs (“soft costs”) for utility-scale solar project development. In order to accomplish the third project objective – including a measure of social risk and public acceptance within PVMapper – the project team has developed a time-series public opinion survey, administered yearly over the course of the three-year project. This report highlights the results and preliminary analyses from the second survey in this series. While the results of this survey are valuable to both PVMapper and future utility-scale solar development, the time-series design is extremely important. The completion of the series enables the extension of the dataset to much richer information. For example, the research team altered this iteration to sharpen the focus on specific topics (those posing potentially higher risks) and target specific locations in the oversample (such as communities near existing facilities). Using similar

  12. Post-concussion driving behaviors and opinions: A survey of collegiate student-athletes.

    Science.gov (United States)

    Schmidt, Julianne D; Lynall, Robert C; Lempke, Landon Bryce; Weber, Michelle L; Devos, Hannes

    2018-05-08

    Post-concussion driving restrictions are eminent, but we lack understanding of current behaviors and opinions about driving following concussion among populations at risk of concussion. We aimed to describe post-concussion driving behaviors and opinions among collegiate student-athletes. Student-athletes completed a survey (response rate=45.3%, 223/492) regarding their post-concussion driving behaviors and opinions. Response frequencies and percentages are presented. Student-athletes self-reported a total of 169 lifetime concussions (0.76±1.02 each). Of the 169 concussions, 52.1% (88/169) were diagnosed and 52.7% (89/169) occurred while the student-athlete possessed a valid driver's license. Student-athletes refrained from driving following 43.8% (39/89) of the concussive events. Student-athletes that refrained most commonly did so for only 24-48 hours (20.5%, 8/39) and because a health care provider advised them to (33.3%: 13/39). Student-athletes most commonly reported that they would feel "very unsafe" driving a car immediately following injury (38.4%, 84/219). When asked whether driving restrictions would influence your decision to report the injury to a health care provider, 7.9% reported that it "definitely would" (17/214), 26.6% "probably would" (57/214), 17.8% "neutral" (38/214), 24.8% "probably would not" (53/214), and 22.9% "definitely would not" (49/214). Despite generally believing that driving immediately following a concussion is unsafe, a majority of student-athletes did not refrain from driving at any point following their previous concussions. Post-concussion driving restrictions may have some influence on student-athletes' decisions to report the injury to a health care provider. Health care providers play a critical role in post-concussion driving restriction, but lack standardized recommendations to guide their care.

  13. Exploring Digital Health Use and Opinions of University Students: Field Survey Study.

    Science.gov (United States)

    Montagni, Ilaria; Cariou, Tanguy; Feuillet, Tiphaine; Langlois, Emmanuel; Tzourio, Christophe

    2018-03-15

    During university, students face some potentially serious health risks, and their lifestyle can have a direct effect on health and health behaviors later in life. Concurrently, university students are digital natives having easy access to the internet and new technologies. Digital health interventions offer promising new opportunities for health promotion, disease prevention, and care in this specific population. The description of the current use of and opinions on digital health among university students can inform future digital health strategies and interventions within university settings. The aim of this exploratory study was to report on university students' use and opinions regarding information and communication technologies for health and well-being, taking into account sociodemographic and self-rated general and mental health correlates. This field survey was conducted from March to April 2017. An informed consent form and a paper questionnaire were given to students aged 18 to 24 years in 4 university campuses in Bordeaux, France. The survey was formulated in 3 sections: (1) sociodemographic characteristics and self-rated general and mental health, (2) information about the use of digital health, and (3) opinions about digital health. Data were analyzed using descriptive statistics and tests of independence. A total of 59.8% (303/507 females) students completed the questionnaire. Concerning digital health use, 34.9% (174/498) had at least 1 health app mostly for physical activity (49.4%, 86/174) and general health monitoring (41.4%, 72/174,), but only 3.9% (20/507) of students had a wearable device. Almost all (94.8%, 450/476) had searched for Web-based health-related information at least once in the last 12 months. The most sought health-related topics were nutrition (68.1%, 324/476); pain and illnesses (64.5%, 307/476); and stress, anxiety, or depression (51.1%, 243/476). Although Wikipedia (79.7%, 357/448) and general health websites (349/448, 77

  14. Exploring Digital Health Use and Opinions of University Students: Field Survey Study

    Science.gov (United States)

    Cariou, Tanguy; Feuillet, Tiphaine; Langlois, Emmanuel; Tzourio, Christophe

    2018-01-01

    Background During university, students face some potentially serious health risks, and their lifestyle can have a direct effect on health and health behaviors later in life. Concurrently, university students are digital natives having easy access to the internet and new technologies. Digital health interventions offer promising new opportunities for health promotion, disease prevention, and care in this specific population. The description of the current use of and opinions on digital health among university students can inform future digital health strategies and interventions within university settings. Objective The aim of this exploratory study was to report on university students’ use and opinions regarding information and communication technologies for health and well-being, taking into account sociodemographic and self-rated general and mental health correlates. Methods This field survey was conducted from March to April 2017. An informed consent form and a paper questionnaire were given to students aged 18 to 24 years in 4 university campuses in Bordeaux, France. The survey was formulated in 3 sections: (1) sociodemographic characteristics and self-rated general and mental health, (2) information about the use of digital health, and (3) opinions about digital health. Data were analyzed using descriptive statistics and tests of independence. Results A total of 59.8% (303/507 females) students completed the questionnaire. Concerning digital health use, 34.9% (174/498) had at least 1 health app mostly for physical activity (49.4%, 86/174) and general health monitoring (41.4%, 72/174,), but only 3.9% (20/507) of students had a wearable device. Almost all (94.8%, 450/476) had searched for Web-based health-related information at least once in the last 12 months. The most sought health-related topics were nutrition (68.1%, 324/476); pain and illnesses (64.5%, 307/476); and stress, anxiety, or depression (51.1%, 243/476). Although Wikipedia (79.7%, 357/448) and

  15. Report of the survey on current opinions and practice of German Society for Gynecologic Endoscopy (AGE) members regarding the laparoscopic treatment of ovarian malignancies.

    Science.gov (United States)

    Radosa, Julia Caroline; Radosa, Marc Philipp; Schweitzer, Pascal Albert; Juhasz-Boess, Ingolf; Rimbach, Stefan; Solomayer, Erich-Franz

    2018-05-01

    The purpose of this survey was to assess the opinions of members of the German Society of Gynecologic Endoscopy (AGE) regarding the laparoscopic treatment of ovarian malignancies and current practice at their institutions. Between February and October 2015, the AGE sent an anonymous online survey via mail to its members. The questionnaire solicited participants' opinions about the laparoscopic treatment of ovarian cancers according to T stage and borderline tumors, and information about current practice at their institutions. Participants were also asked their opinions on currently available data on this issue. Of 228 AGE members who completed the survey, 132 (58%) were fellows or attending physicians and 156 (68%) worked at university hospitals or tertiary referral centers. Most [212 (93%)] respondents stated that < 10% of all ovarian cancer cases were currently treated laparoscopically at their institutions. Most participants indicated that T1 (a, b, c) tumors [145 (64%)] and ovarian borderline tumors [206 (90%)], but not T2 [48 (21%)] or T3/4 [9 (4%) ovarian tumors] should or could be treated laparoscopically. One hundred seventy-two (75%) participants considered currently available data on this topic to be insufficient and 152 (66%) stated that they would take part in a clinical trial assessing a laparoscopic approach to T1/2 ovarian cancer. According to this survey, to the opinion of the majority of AGE members, laparoscopy might be a considerable option for the treatment of early ovarian malignancies and borderline tumors and should be evaluated further in future studies.

  16. Opinions of patients with type 2 diabetes about responsibility, setting targets and willingness to take medication: a cross-sectional survey.

    NARCIS (Netherlands)

    Gorter, K.J.; Tuytel, G.J.; Leeuw, R.R. de; Bensing, J.M.; Rutten, G.E.H.M.

    2011-01-01

    OBJECTIVE: To assess opinions and their determinants of patients with type 2 diabetes about responsibility for managing their diabetes, setting treatment targets and willingness taking medication. METHODS: Questionnaire survey carried out in general practices and outpatient clinics across the

  17. Generation of Chimeric RNAs by cis-splicing of adjacent genes (cis-SAGe) in mammals.

    Science.gov (United States)

    Zhuo, Jian-Shu; Jing, Xiao-Yan; Du, Xin; Yang, Xiu-Qin

    2018-02-20

    Chimeric RNA molecules, possessing exons from two or more independent genes, are traditionally believed to be produced by chromosome rearrangement. However, recent studies revealed that cis-splicing of adjacent genes (cis- SAGe) is one of the major mechanisms underlying the formation of chimeric RNAs. cis-SAGe refers to intergenic splicing of directly adjacent genes with the same transcriptional orientation, resulting in read-through transcripts, termed chimeric RNAs, which contain sequences from two or more parental genes. cis-SAGe was first identified in tumor cells, since then its potential in carcinogenesis has attracted extensive attention. More and more scientists are focusing on it. With the development of research, cis-SAGe was found to be ubiquitous in various normal tissues, and might make a crucial contribution to the formation of novel genes in the evolution of genomes. In this review, we summarize the splicing pattern, expression characteristics, possible mechanisms, and significance of cis-SAGe in mammals. This review will be helpful for general understanding of the current status and development tendency of cis-SAGe.

  18. 'Quicksand' of public opinion - trust in nuclear after Fukushima

    International Nuclear Information System (INIS)

    Gieci, Adam; Maly, Stanislav; Palecek, Milos

    2012-01-01

    The following public opinion surveys are described: public opinion on nuclear power plants by the end of 2010; first public opinion polls after Fukushima in the US, UK and France; and public opinion and the future of nuclear in Japan. The following issues are discussed: Has nuclear any perspective after Fukushima? Will public opinion change after the Fukushima accident like it did after the TMI event? Will public opinion change after the Fukushima accident like it did after the oil spill accident in the Gulf of Mexico? In conclusion the new approaches to the fight for public confidence after Fukushima are described. (orig.)

  19. A survey of consumer’ opinion about consumption and health benefits of fermented plant beverages in Thailand

    Directory of Open Access Journals (Sweden)

    Chaiyavat CHAIYASUT

    2017-10-01

    Full Text Available Abstract Fermented beverages are widely used all over the country. Fermented plant beverages (FPB are prevalent in Thailand and FPBs are believed to cure and prevent many health oriented problems. The people of Thailand produce many varieties of FPBs in small scale or large scale and consume them in their daily lives. This study is a survey conducted among the representative consumers of FPBs in Thailand to know the consumer's opinion on FPBs, effects and benefits of FPBs, and real status of consumer satisfaction in Thailand. This study revealed that the rationale for the consumption of respective FPBs was to treat their health issues and for the betterment of their health. Most of the consumers of FPBs benefited in case of improving their physical and mental health. The current survey revealed the opinion of the FPBs consumers in Thailand. This study concluded that FPBs are health promoting drink that is affordable in the daily life of Thai people. The FPBs prepared in Thailand did not report any massive adverse effects in Thailand. Till now the preparation and consumption of FPBs are followed in Thailand and not influenced by adverse effects; FPBs are considered safe for human consumption.

  20. survey of opinions in a paediatric department

    African Journals Online (AJOL)

    1991-05-04

    May 4, 1991 ... Doctors working at 3 teaching hospitals of the University of the Witwatersrand were .... study. It can therefore be assumed that the opinions put forth were largely .... and will, it is hoped, provide some food for thought for other departments. ... Puhlic Health 'Service guidelioes for counselliog and antibody ...

  1. Opinion of stakeholders on existing curriculum for postgraduate (MD) course in Pharmacology: A survey.

    Science.gov (United States)

    Badyal, Dinesh K; Daniel, Sujit R

    2016-10-01

    To survey the opinion about various curricular components of Doctor of Medicine (MD) pharmacology curriculum in India by stakeholders, including faculty and students. An online survey was done to evaluate the various curricular components of MD pharmacology curriculum being used in India. A total of 393 respondents including faculty, MD students, and other stakeholders completed the survey. The survey was developed using SurveyMonkey platform and link to survey was E-mailed to stakeholders. The results were expressed as percentages. There was a balanced representation of respondents from various designations, teaching experience, regions, and age groups. Most of the respondents (83%) were aware of the MD pharmacology curriculum. However, they reported that it is more inclined to knowledge domain. About half of respondents (53%) said that animal experiments are being used. The most common teaching methods mentioned are seminars (98.5%), journal clubs (95%), and practical exercises by postgraduates (73%), but there is less use of newer methods (25%) in theory and less of clinical pharmacology exercise (39%) in practical classes. The log books are maintained but not assessed regularly. Internal assessment is sparingly used. The MD pharmacology curriculum needs to be made uniform at the national level and updated to include the newer methods in teaching-learning and assessment. There should be sharing of newer methods at a common platform implemented at the national level.

  2. Introduction of direct-to-consumer advertising of prescription drugs in Canada: an opinion survey on regulatory policy.

    Science.gov (United States)

    Mintzes, Barbara; Barer, Morris; Lexchin, Joel; Bassett, Ken L

    2005-06-01

    Canada is strongly influenced by US cross-border direct-to-consumer advertising (DTCA) and has held consultations to discuss introduction of DTCA since 1996. This article describes a survey of Canadian drug policy experts carried out in 2001, during one such legislative review. The survey results are compared to more recent DTCA policy developments. We recruited key informants on pharmaceutical policy to complete a faxed questionnaire that queried their opinions on DTCA information quality, effects on drug and health care use, and regulatory issues. Respondents were asked about the evidence they had used to back their opinions. Analysis was descriptive. Of 79 identified potential participants, 60 (76%) participated, 40% of whom were from federal and provincial government; 3% were private insurers; 18%, 15%, and 8% were from health professional groups, consumer groups, and patient groups, respectively; 8% and 7% were from pharmaceutical and advertising industries, respectively. Opinions were highly polarized on the effects of DTCA on drug and health care use. Advertising and pharmaceutical industry respondents were generally positive, public sector, health professional and consumer groups generally negative. Over 80% believed DTCA leads to higher private and public drug costs and more frequent physician visits. Fewer judged billboards or television to be appropriate media for DTCA than magazines or the Internet, and most believed that children and adolescents should not be targeted. Given the polarization observed within this survey, we examined how DTCA policy has evolved in Canada since 2001. The federal government has legislative authority over DTCA, but bears few of the additional costs potentially incurred through policy change. These fall to the provinces, which provide an eroding patchwork of public coverage for prescription drugs in the face of rapidly increasing costs. No new federal legislation has been tabled since 2001. However, considerable shifts in

  3. Do Others’ Opinion Matter?

    DEFF Research Database (Denmark)

    Liu, Fei; Xiao, Bo Sophia; Lim, Eric T. K.

    2016-01-01

    when experiencing dissonance in e-WOM, male consumers value opinionated review over numerical rating and vice versa for their female counterparts. The results of our field survey on a custom developed website with 115 college students empirically validated our hypothesized relationships and also...

  4. STATISTICAL ANALYSIS AND OPINION SURVEY UPON DICTATORSHIP AS A PEDAGOGICAL STRATEGY OF THE TEACHING OF HISTORY.

    Directory of Open Access Journals (Sweden)

    Vitória A. da Fonseca

    2016-07-01

    Full Text Available This paper presents a practice of teaching, whose purpose was to make students of high school capable of understanding the issues upon the dictatorship as a theme in the teaching of history. Considering the importance of practice as a tool which makes up a learning path, the activity has involved debate, survey and statistical analysis. It is worth highlighting the engagement of students in this activity and mapping of their opinions about the dictatorship.

  5. Surveyed opinion of American trauma, orthopedic, and thoracic surgeons on rib and sternal fracture repair.

    Science.gov (United States)

    Mayberry, John C; Ham, L Bruce; Schipper, Paul H; Ellis, Thomas J; Mullins, Richard J

    2009-03-01

    Rib and sternal fracture repair are controversial. The opinion of surgeons regarding those patients who would benefit from repair is unknown. Members of the Eastern Association for the Surgery of Trauma, the Orthopedic Trauma Association, and thoracic surgeons (THS) affiliated with teaching hospitals in the United States were recruited to complete an electronic survey regarding rib and sternal fracture repair. Two hundred thirty-eight trauma surgeons (TRS), 97 orthopedic trauma surgeons (OTS), and 70 THS completed the survey. Eighty-two percent of TRS, 66% of OTS, and 71% of THS thought that rib fracture repair was indicated in selected patients. A greater proportion of surgeons thought that sternal fracture repair was indicated in selected patients (89% of TRS, 85% of OTS, and 95% of THS). Chest wall defect/pulmonary hernia (58%) and sternal fracture nonunion (>6 weeks) (68%) were the only two indications accepted by a majority of respondents. Twenty-six percent of surgeons reported that they had performed or assisted on a chest wall fracture repair, whereas 22% of surgeons were familiar with published randomized trials of the surgical repair of flail chest. Of surgeons who thought rib fracture or sternal fracture repair was rarely, if ever, indicated, 91% and 95%, respectively, specified that a randomized trial confirming efficacy would be necessary to change their negative opinion. A majority of surveyed surgeons reported that rib and sternal fracture repair is indicated in selected patients; however, a much smaller proportion indicated that they had performed the procedures. The published literature on surgical repair is sparse and unfamiliar to most surgeons. Barriers to surgical repair of rib and sternal fracture include a lack of expertise among TRS, lack of research of optimal techniques, and a dearth of randomized trials.

  6. Perception of risks by opinion leaders 2011

    International Nuclear Information System (INIS)

    2011-01-01

    The authors report a survey made just after the Fukushima accident on a panel of opinion leaders (belonging to political, economical or media sector) in order to compare their perception of risks with that of the public. The questions addressed the perception of risks, the role of scientific experts, the usefulness and breaks on the diffusion of expertise results, the perception of pluralist bodies, and the Fukushima accident. The answers are analysed and discussed with respect to fifteen hazardous situations, to their opinion of expertise, and to their opinion on safety audit and information

  7. Public opinion on nuclear power. Results of 15-year continuous survey

    International Nuclear Information System (INIS)

    Kitada, Atsuko

    2008-01-01

    Since 1993 the Institute of Nuclear Safety System (INSS) has conducted 11 public opinion surveys as part of a longitudinal research to find out the characteristics and trend of public attitudes toward nuclear power generation. During this period, a spate of nuclear-related incidents occurred: the Monju accident; the JCO criticality accident; a cover-up of problems by Tokyo Electric Power Company; power shortage in the Tokyo metropolitan area caused by the suspension of nuclear power plant operation; and the Mihama Unit 3 steam explosion. In addition to regular surveys, the INSS conducted surveys two months after each incident to assess the impact of the event on public attitudes. Our findings are as follows: As uneasiness easily changes responding to an event in society, there were changes in uneasiness about nuclear power after accidents. Although the majority of the public accept the use of nuclear power generation, they do so out of necessity. This attitude of passive support remained unchanged even after accidents. As the prime reason for supporting nuclear power generation, respondents consistently cited diversification of energy sources. In recent years, there were slight increases in the number of respondents who cite issues related to energy situation and global warming. Three major reasons for non-support are radio-active contamination, risk of a catastrophic accident and radioactive waste. No impact of accidents was observed in this regard. In the previous post-accident surveys, negative effects were observed mainly in terms of uneasiness about the accident and risk of an accident, corporate image associated with the accident and confidence in safety. However, these changes were insignificant, the rates of changes below ten-odd percent. As time passed, recognition of the accident or incident lowered and attitudes recovered. It was confirmed that the negative effects were temporary. (author)

  8. Taxes on sugar-sweetened beverages: results from a 2011 national public opinion survey.

    Science.gov (United States)

    Barry, Colleen L; Niederdeppe, Jeff; Gollust, Sarah E

    2013-02-01

    Consumption of sugar-sweetened beverages including nondiet sodas, sport drinks, and energy drinks has been linked with obesity. Recent state and local efforts to tax these beverages have been unsuccessful. Enactment will be unlikely without public support, yet little research is available to assess how to effectively make the case for such taxes. The objectives were to assess public opinion about arguments used commonly in tax debates regarding sugar-sweetened beverages and to assess differences in public opinion by respondents' political party affiliation. A public opinion survey was fielded in January-March 2011 using a probability-based sample of respondents from a large, nationally representative online panel to examine public attitudes about nine pro- and eight anti-tax arguments. These data were analyzed in August 2011. Findings indicated greater public agreement with anti- than pro-tax arguments. The most popular anti-tax argument was that a tax on sugar-sweetened beverages is arbitrary because it does not affect consumption of other unhealthy foods (60%). A majority also agreed that such taxes were a quick way for politicians to fill budget holes (58%); an unacceptable intrusion of government into people's lives (53.8%); opposed by most Americans (53%); and harmful to the poor (51%). No pro-tax arguments were endorsed by a majority of the public. Respondents reported highest agreement with the argument that sugar-sweetened beverages were the single largest contributor to obesity (49%) and would raise revenue for obesity prevention (41%). Without bolstering public support for existing pro-tax messages or developing alternative pro-tax messages, enacting such policies will be difficult. Message-framing studies could be useful in identifying promising strategies for persuading Americans that taxes on sugar-sweetened beverages are warranted. Copyright © 2013 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  9. IRSN 2017 opinion survey. The perception of risks and safety by French people. Global results

    International Nuclear Information System (INIS)

    El Jammal, Marie-Helene; Charron, Sylvie; Mur, Emmanuelle; Schuler, Matthieu; Tchernia, Jean-francois

    2017-07-01

    Like every year, this report presents and comments the results of an opinion survey on risks, and more particularly on risks related to nuclear and radiological activities. The first part addresses the current concerns of French people (main concerns in the present society, with respect to the environment, and risks related to industrial installations). The second part addresses the opinion on expertise (the role and image of experts, diffusion and sharing of scientific expertise, and the perception of pluralistic structures). The third part examines the reaction of people in front of 34 different hazardous situations (risks to which people feel being exposed, confidence people have in authorities to protect them, confidence in information on hazards, hierarchy of the 34 situations according to three different aspects, and relationship with installation acceptability). The fourth part addresses the nuclear domain: expectations related to the control of the nuclear risk, benefits and drawbacks of nuclear energy, fear of a severe accident, attention given by French people to nuclear energy, expertise and credibility of interveners in the nuclear sector

  10. IRSN 2016 opinion survey. The perception of risks and safety by French people. Global results

    International Nuclear Information System (INIS)

    El Jammal, Marie-Helene; Charron, Sylvie; Mur, Emmanuelle; Schuler, Matthieu; Tchernia, Jean-francois

    2016-07-01

    Like every year, this report presents and comments the results of an opinion survey on risks, and more particularly on risks related to nuclear and radiological activities. The first part addresses the current concerns of French people (main concerns in the present society, with respect to the environment, and risks related to industrial installations). The second part addresses the opinion on expertise (the role and image of experts, diffusion and sharing of scientific expertise, and the perception of pluralistic structures). The third part examines the reaction of people in front of 34 different hazardous situations (risks to which people feel being exposed, confidence people have in authorities to protect them, confidence in information on hazards, hierarchy of the 34 situations according to three different aspects, and relationship with installation acceptability). The fourth part addresses the nuclear domain: expectations related to the control of the nuclear risk, fear of a severe accident, benefits and drawbacks of nuclear energy, expertise and credibility of interveners in the nuclear sector, fear of serious nuclear accidents, perception of the two main nuclear accidents: Chernobyl (1986) and Fukushima (2011)

  11. Decision no 2009-DC-0158 of the 15. of September 2009 by the Nuclear Safety Authority specifying instructions related to modalities of water sampling and consumption, and of release in the environment of liquid and gaseous effluents from the base nuclear installation n. 29 operated by the CIS Bio International on the district of Saclay (Essonne department)

    International Nuclear Information System (INIS)

    2009-01-01

    After references to the different legal and official documents (codes, orders, minister's opinion, public surveys, administrative authorizations, local community opinion), this document specifies the instructions related to modalities of water sampling and consumption, and of release in the environment of liquid and gaseous effluents from the base nuclear installation operated by CIS Bio International in Saclay. These instructions and provisions concern the general means implemented by the operator, records, the control by authorities, the limits of water sampling and consumption, the water sampling process, the sampling works and their maintenance and control, the release of liquid, gaseous and radioactive effluents, their control and their transfer, the limit values for different compounds and species, the control of environment around the site, the information of authorities and of population

  12. IRSN opinion survey - The perception of risks and security by the French population. Global results June 2013

    International Nuclear Information System (INIS)

    2013-06-01

    After having commented the most remarkable results (importance of the economic crisis as a major concern for French people before environmental concerns, an improved perception of industrial risks, the Fukushima accident is fading away but specific traces remain, expectations regarding nuclear energy), this report, illustrated by several graphs, presents and discusses the results of an annual opinion survey on the present concerns of French people (in the present society, for the environment, and as far as science is concerned), the opinion of French people on expertise (about who must control a risky installation, about the role and image of scientific experts, about the diffusion and sharing of scientific expertise, and about the perception of pluralistic structures), on the attitude of French people in front of 33 risk situations (risks to which French people feel exposed to, confidence of French people in authorities to protect them, the truth of information on hazards, the hierarchy of 33 situations according to three aspects and their relationship with installation acceptability). The fourth part addresses more particularly the nuclear sector: nuclear risk, ability and credibility of interveners, debate on energy transition. A last part addresses the perception of the Fukushima accident. Graphs notably present the evolution of opinions with respect to last year or over the past years

  13. MicroRNA signature of cis-platin resistant vs. cis-platin sensitive ovarian cancer cell lines

    Directory of Open Access Journals (Sweden)

    Kumar Smriti

    2011-09-01

    Full Text Available Abstract Background Ovarian cancer is the leading cause of death from gynecologic cancer in women worldwide. According to the National Cancer Institute, ovarian cancer has the highest mortality rate among all the reproductive cancers in women. Advanced stage diagnosis and chemo/radio-resistance is a major obstacle in treating advanced ovarian cancer. The most commonly employed chemotherapeutic drug for ovarian cancer treatment is cis-platin. As with most chemotherapeutic drugs, many patients eventually become resistant to cis-platin and therefore, diminishing its effect. The efficacy of current treatments may be improved by increasing the sensitivity of cancer cells to chemo/radiation therapies. Methods The present study is focused on identifying the differential expression of regulatory microRNAs (miRNAs between cis-platin sensitive (A2780, and cis-platin resistant (A2780/CP70 cell lines. Cell proliferation assays were conducted to test the sensitivity of the two cell lines to cis-platin. Differential expression patterns of miRNA between cis-platin sensitive and cis-platin resistant cell lines were analyzed using novel LNA technology. Results Our results revealed changes in expression of 11 miRNAs out of 1,500 miRNAs analyzed. Out of the 11 miRNAs identified, 5 were up-regulated in the A2780/CP70 cell line and 6 were down regulated as compared to cis-platin sensitive A2780 cells. Our microRNA data was further validated by quantitative real-time PCR for these selected miRNAs. Ingenuity Pathway Analysis (IPA and Kyoto Encyclopedia of Genes and Genomes (KEGG analysis was performed for the selected miRNAs and their putative targets to identify the potential pathways and networks involved in cis-platin resistance. Conclusions Our data clearly showed the differential expression of 11 miRNAs in cis-platin resistant cells, which could potentially target many important pathways including MAPK, TGF-β signaling, actin cytoskeleton, ubiquitin mediated

  14. A survey of South African provincial netball coaches\\' opinions ...

    African Journals Online (AJOL)

    South African Journal for Research in Sport, Physical Education and Recreation ... coaches\\' opinions, abilities and limitations regarding mental skills training ... competitions (according to their coaches), with the rest (44.44%) showing average

  15. IRSN 2015 opinion survey. The perception of risks and safety by French people. Global results

    International Nuclear Information System (INIS)

    El Jammal, Marie-Helene; Mur, Emmanuelle; Rollinger, Francois; Schuler, Matthieu; Tchernia, Jean-Francois

    2015-07-01

    Like every year, this report presents and comments the results of an opinion survey on risks, and more particularly on risks related to nuclear and radiological activities. The first part addresses the current concerns of French people (main concerns in the present society, with respect to the environment, and risks related to industrial installations). The second part addresses the opinion on expertise (the role and image of experts, diffusion and sharing of scientific expertise, and who should control a hazardous installation). The third part examines the reaction of people in front of 34 different hazardous situations (risks to which people feel being exposed, confidence people have in authorities to protect them, confidence in information on hazards, hierarchy of the 34 situations according to three different aspects, and relationship with installation acceptability). The fourth part addresses the nuclear domain: expectations related to the control of the nuclear risk, fear of a severe accident, benefits and drawbacks of nuclear energy, expertise and credibility of interveners in the nuclear sector. The fifth part addresses the presence of radon in dwellings (awareness of the risk, measures related to the control of radon in dwellings)

  16. Public opinion on atomic energy after JCO accident

    International Nuclear Information System (INIS)

    Okamoto, Koichi; Miyamoto, Sosuke; Ishikawa, Masayori; Shimomura, Hideo; Hori, Hiromoto; Suzuki, Yasuko; Kamise, Yumiko

    2004-04-01

    JCO accident happened on September 30, 1999. This book deals with the public opinion of atomic energy after JCO accident in Japan and comparison with that of USA and France. The analysis of public opinion structure is also shown. The important chapter is the eighth chapter a n opinion survey after the accident , of which sampling areas consisted of three areas such as JCO accident area, the nuclear power plants and the general cities. The analytical results of data showed that the public opinion in Tokai-mura and Naka-machi, the JCO accident area, indicated moderate opinions. It is the interesting results were obtained that the moderate tendency of opinion was in order JCO accident area, the nuclear power plants and the general cities. People's attitude toward nuclear energy related to their social values. Abstract of JCO accident, JCO structure, the effects of accident on the environment and news stories about the accident are reported. (S.Y.)

  17. (Miscommunication across the Borders: Politics, Media and Public Opinion in Turkey

    Directory of Open Access Journals (Sweden)

    Banu Baybars-Hawks

    2015-08-01

    Full Text Available The American sociologist Charles Horton Cooley defined public opinion "as a process of interaction and mutual influence rather than a state of broad agreement" in 1918. On the other hand, according to the American political scientist V.O. Key, public opinion was "opinions held by private persons which governments find it prudent to heed," in 1961. During the 1990s, advances in statistical and demographic analysis helped the development of an understanding of public opinion as the collective view of a defined population, such as a particular demographic or ethnic group. In this view, the influence of public opinion is not restricted to politics and elections. Public opinion is considered a powerful force in many other spheres, such as culture, fashion, literature and the arts, consumer spending, and marketing and public relations.1 Attitudes and values play a crucial role in the development of public opinion. Different variables embedded in the political, social and media structure of the country also have potential to make an impact on public opinion. These dynamics vary from the economics to the judicial system and democratic principles functioning in that country. On the other hand, public opinion has a power to shape politics and media's priorities in reporting. The interaction among politics, public opinion and media of one country can be better analyzed with the findings of public opinion research administered regularly. In Turkey, the research on and analysis of public opinion are most frequent during the election times. Therefore, it seems necessary to measure the public opinion more regularly to test the relationships among political, public and media agendas. Accordingly, the current study seeks to fill this gap. It is argued that in the absence of timely feedback from public surveys, decisions and policies for improving different services and institutions functioning in the country might not achieve their expected goal. The findings of

  18. cis sequence effects on gene expression

    Directory of Open Access Journals (Sweden)

    Jacobs Kevin

    2007-08-01

    Full Text Available Abstract Background Sequence and transcriptional variability within and between individuals are typically studied independently. The joint analysis of sequence and gene expression variation (genetical genomics provides insight into the role of linked sequence variation in the regulation of gene expression. We investigated the role of sequence variation in cis on gene expression (cis sequence effects in a group of genes commonly studied in cancer research in lymphoblastoid cell lines. We estimated the proportion of genes exhibiting cis sequence effects and the proportion of gene expression variation explained by cis sequence effects using three different analytical approaches, and compared our results to the literature. Results We generated gene expression profiling data at N = 697 candidate genes from N = 30 lymphoblastoid cell lines for this study and used available candidate gene resequencing data at N = 552 candidate genes to identify N = 30 candidate genes with sufficient variance in both datasets for the investigation of cis sequence effects. We used two additive models and the haplotype phylogeny scanning approach of Templeton (Tree Scanning to evaluate association between individual SNPs, all SNPs at a gene, and diplotypes, with log-transformed gene expression. SNPs and diplotypes at eight candidate genes exhibited statistically significant (p cis sequence effects in our study, respectively. Conclusion Based on analysis of our results and the extant literature, one in four genes exhibits significant cis sequence effects, and for these genes, about 30% of gene expression variation is accounted for by cis sequence variation. Despite diverse experimental approaches, the presence or absence of significant cis sequence effects is largely supported by previously published studies.

  19. Explaining Foreign Direct Investments in Gujarat: A Study based on an Opinion Survey of Persons Involved in the Foreign Direct Investment Process

    OpenAIRE

    Morris, Sebastian

    2005-01-01

    Gujarat has attracted more foreign direct investment (FDI) than what its GDP size alone would suggest. But relative to its peer states (especially Tamilnadu, Delhi, Maharashtra and Karnataka, and possibly Andhra Pradesh) it has fallen short significantly. The above findings which we made in an earlier study are further confirmed through a survey of opinions and views of CEOs and others intimately concerned with the foreign investment decision process. The survey also brought out the crucial i...

  20. Cis-Lunar Base Camp

    Science.gov (United States)

    Merrill, Raymond G.; Goodliff, Kandyce E.; Mazanek, Daniel D.; Reeves, John D., Jr.

    2012-01-01

    Historically, when mounting expeditions into uncharted territories, explorers have established strategically positioned base camps to pre-position required equipment and consumables. These base camps are secure, safe positions from which expeditions can depart when conditions are favorable, at which technology and operations can be tested and validated, and facilitate timely access to more robust facilities in the event of an emergency. For human exploration missions into deep space, cis-lunar space is well suited to serve as such a base camp. The outer regions of cis-lunar space, such as the Earth-Moon Lagrange points, lie near the edge of Earth s gravity well, allowing equipment and consumables to be aggregated with easy access to deep space and to the lunar surface, as well as more distant destinations, such as near-Earth Asteroids (NEAs) and Mars and its moons. Several approaches to utilizing a cis-lunar base camp for sustainable human exploration, as well as some possible future applications are identified. The primary objective of the analysis presented in this paper is to identify options, show the macro trends, and provide information that can be used as a basis for more detailed mission development. Compared within are the high-level performance and cost of 15 preliminary cis-lunar exploration campaigns that establish the capability to conduct crewed missions of up to one year in duration, and then aggregate mass in cis-lunar space to facilitate an expedition from Cis-Lunar Base Camp. Launch vehicles, chemical propulsion stages, and electric propulsion stages are discussed and parametric sizing values are used to create architectures of in-space transportation elements that extend the existing in-space supply chain to cis-lunar space. The transportation options to cis-lunar space assessed vary in efficiency by almost 50%; from 0.16 to 0.68 kg of cargo in cis-lunar space for every kilogram of mass in Low Earth Orbit (LEO). For the 15 cases, 5-year campaign

  1. Cis-trans photoisomerization of abscisic acid

    International Nuclear Information System (INIS)

    Brabham, D.E.; Biggs, R.H.

    1981-01-01

    An important regulator of numerous physiological processes in higher plants is abscisic acid (ABA), which is photoisomerized from the more biologically active cis isomer to the nearly inactive trans isomer by natural sunlight. It is possible that this photoisomerization is a UV control mechanism in functions regulated by ABA. The quantum yields of both the cis to trans and trans to cis photoisomerizations were measured under various conditions of pH and oxygen concentration at room temperature. The yield for photoisomerization of cis-ABA ranged from 0.25 at pH 3.0 to 0.11 at pH 7.0. Oxygen partially quenched the process. The quantum yield varied only slightly with wavelength. The quantum yield of photolysis of cis-ABA was reported for pH 3.0 as 0.06. This yield also varied slightly with wavelength and was relatively insensitive to oxygen. This relatively high yield explains the loss of potency of ABA during UV irradiation. Phosphorescence of cis- and trans-ABA was observed in methanol at 77 K. Onset of the emission was at 350 nm. The emission spectra were the same for both isomers. From these results a mechanism of UV action on plants based on the photoisomerization of the inactive trans-ABA to the biologically active cis isomer is proposed. (author)

  2. Changes in alcohol policies and public opinions in Finland 2003-2013.

    Science.gov (United States)

    Österberg, Esa; Lindeman, Mikaela; Karlsson, Thomas

    2014-05-01

    There is a constant and ongoing interplay between public opinions and public policies, alcohol policies being no exception. This article describes the development of public opinions regarding alcohol policy in Finland during a 10-year period between 2003 and 2013. Fluctuations in the alcohol policy opinion climate are put in context by looking at concurrent changes in alcohol policies and in total alcohol consumption. The study is based on data from opinion surveys on alcohol policies commissioned by the National Institute for Health and Welfare and the Finnish Social and Health Association. The opinion polls include questions about the general acceptance of prevailing alcohol policies, appropriate sales channels of different alcoholic beverage categories and opinions about the legal age limits and prices of alcoholic beverages. In the study, changes in alcohol policy during 2003-2013 are surveyed, and their relationship with changes in alcohol policy opinion is examined. There seem to be a strong positive correlation during the study period between the level of alcohol consumption and the share of those wanting a more restrictive alcohol policy in Finland. It seems that an increased level of awareness of alcohol-related issues among the general public created a more restrictive opinion climate on alcohol policy issues after the big alcohol excise duty decrease in 2004. The reverse seems to happen but in a lesser degree when alcohol excise duties has been increased after the year 2007. © 2014 Australasian Professional Society on Alcohol and other Drugs.

  3. Evaluating cis-2,6-Dimethylpiperidide (cis-DMP) as a Base Component in Lithium-Mediated Zincation Chemistry

    Science.gov (United States)

    Armstrong, David R; Garden, Jennifer A; Kennedy, Alan R; Leenhouts, Sarah M; Mulvey, Robert E; O'Keefe, Philip; O'Hara, Charles T; Steven, Alan

    2013-01-01

    Most recent advances in metallation chemistry have centred on the bulky secondary amide 2,2,6,6-tetramethylpiperidide (TMP) within mixed metal, often ate, compositions. However, the precursor amine TMP(H) is rather expensive so a cheaper substitute would be welcome. Thus this study was aimed towards developing cheaper non-TMP based mixed-metal bases and, as cis-2,6-dimethylpiperidide (cis-DMP) was chosen as the alternative amide, developing cis-DMP zincate chemistry which has received meagre attention compared to that of its methyl-rich counterpart TMP. A new lithium diethylzincate, [(TMEDA)LiZn(cis-DMP)Et2] (TMEDA=N,N,N′,N′-tetramethylethylenediamine) has been synthesised by co-complexation of Li(cis-DMP), Et2Zn and TMEDA, and characterised by NMR (including DOSY) spectroscopy and X-ray crystallography, which revealed a dinuclear contact ion pair arrangement. By using N,N-diisopropylbenzamide as a test aromatic substrate, the deprotonative reactivity of [(TMEDA)LiZn(cis-DMP)Et2] has been probed and contrasted with that of the known but previously uninvestigated di-tert-butylzincate, [(TMEDA)LiZn(cis-DMP)tBu2]. The former was found to be the superior base (for example, producing the ortho-deuteriated product in respective yields of 78 % and 48 % following D2O quenching of zincated benzamide intermediates). An 88 % yield of 2-iodo-N,N-diisopropylbenzamide was obtained on reaction of two equivalents of the diethylzincate with the benzamide followed by iodination. Comparisons are also drawn using 1,1,1,3,3,3-hexamethyldisilazide (HMDS), diisopropylamide and TMP as the amide component in the lithium amide, Et2Zn and TMEDA system. Under certain conditions, the cis-DMP base system was found to give improved results in comparison to HMDS and diisopropylamide (DA), and comparable results to a TMP system. Two novel complexes isolated from reactions of the di-tert-butylzincate and crystallographically characterised, namely the pre-metallation complex [{(iPr)2N(Ph)C=O}LiZn(cis

  4. Comparative evaluation of capillary electrophoresis and high-performance liquid chromatography for the separation of cis-cis, cis-trans, and trans-trans isomers of atracurium besylate.

    Science.gov (United States)

    de Moraes, M de L; Polakiewicz, B; Mattua, M F; Tavares, M F

    1998-01-01

    Atracurium besylate is a highly selective nondepolarizing neuromuscular blocking agent routinely used during anesthetic procedures. The commercial presentation of this drug is a mixture of positional isomers, cis-cis, cis-trans, and trans-trans. Reversed-phase high-performance liquid chromatography has been the technique of choice for the analysis of atracurium besylate formulations at the quality control laboratory of Núcleo de Desenvolvimento Cristália (São Paulo, Brazil), a local pharmaceutical company. HPLC analysis is usually conducted under gradient elution using acetonitrile/0.1 M phosphate buffer eluent mixture as mobile phase and an octadecyl silica (ODS)-packed column. The complete elution of the three isomers takes about 1 hr. In this work, an alternative capillary electrophoresis methodology was developed. The complete resolution of all three isomers was accomplished in about 13 min (+20 kV/72 cm, 211 nm direct detection) using a 60-mM phosphate buffer solution (pH 4) containing 20 mM beta-cyclodextrin and 4 M urea. The isomer ratio was found to be 59.1% cis-cis, 35.9% cis-trans, and 5.02% trans-trans (expected ratio: 59:35:6). Laudanosine, a major metabolite of atracurium besylate, was identified in two commercially available formulations, Tracur (Núcleo de Desenvolvimento Cristália) and Tracrium (Glaxo Wellcome, S.A., Rio de Janeiro, Brazil). Its concentration increases considerably during storage of the product, even if the product is stored at low temperatures.

  5. University Opinion Poll 9: Child Care, MPIRG, Lettuce. Preliminary Report.

    Science.gov (United States)

    Matross, Ronald; And Others

    The University Opinion Poll conducted a survey of student opinion on issues related to University-sponsored day care, the role of the Minnesota Public Interest Research Group (MPIRG) and the University's policy on buying lettuce for its food services. Four hundred fifty-two respondents, 76% of a random sample of University of Minnesota students,…

  6. Informing decision making in agricultural greenhouse gas mitigation policy: A Best–Worst Scaling survey of expert and farmer opinion in the sheep industry

    International Nuclear Information System (INIS)

    Jones, A.K.; Jones, D.L.; Edwards-Jones, G.; Cross, P.

    2013-01-01

    Highlights: ► Effectiveness and practicality of greenhouse gas mitigation measures are assessed. ► Best–Worst Scaling surveys are used to elicit expert and sheep farmer opinion. ► Effective and practical measures are priority candidates for policy inclusion. ► Support mechanisms may be needed to deliver effective, low practicality measures. ► Variation in farmers’ perceptions of practicality holds implications for policy delivery. -- Abstract: Policy decision making for agricultural greenhouse gas mitigation is hindered by scientific uncertainty regarding the effectiveness of mitigation measures. Successful on-farm adoption of measures is contingent upon farmer perception of the relative practicality of implementing the measure and associated incentives and advice. In the absence of a comprehensive evidence base we utilised Best–Worst Scaling, a discrete choice survey method, to elicit expert and farmer opinion on the relative effectiveness and practicality of mitigation measures to reduce greenhouse gas emissions from sheep production systems. The method enabled individual mitigation measures to be ranked on a ratio scale of effectiveness (expert opinion) and practicality (farmer opinion). Six measures were identified as possessing the combined qualities of effectiveness and practicality and are considered priority candidates for policy promotion. The overall preferred measure was the use of legumes in pasture reseed mixes. Estimation and analysis of the distribution of individual respondent scores revealed heterogeneity in farmers’ perceptions of practicality, suggesting that flexible policies are required to enable farmers to select mitigation measures most suited to their farm type and locality. Practical measures with below average effectiveness may be widely adopted with limited regulation, incentivisation or advice, whilst some highly effective measures with lower practicality are likely to present greater obstacles to adoption

  7. The current state of radiation education in schools and results of the opinion survey on radiation

    International Nuclear Information System (INIS)

    Murai, Kenji

    2013-01-01

    In 2008, a new guideline about radioactivity was added to the government guidelines for teaching junior high school science. Since then people involved with school education have been trying to spread correct information about radioactivity. On the other hand, people's confusion in the aftermath of the Fukushima Daiichi Nuclear Power Plant accident has clearly shown that people do not know much about radioactivity. Considering the situation, the author conducted an investigation about the current state of radiation education and carried out an opinion survey about radioactivity among adults. The investigation about education showed the following: (1) the nature of radiation, such as its permeability, and its uses were described in the government-approved textbooks; (2) basic knowledge, such as what are radiation effects, were described comprehensively in the supplementary reading recommendations made by the Ministry of Education, Culture, Sports, Science, and Technology; and (3) locale education committees created teaching materials such as guidance to present topics. The opinion survey had questions to judge: (1) current public understanding of radioactivity; (2) the degree of general information that people collected for themselves; (3) the degree of specific knowledge about radioactivity that people had; and (4) people's attitudes toward various problems with radioactivity in the environment. The results suggested that for radiation education the following items are important: (1) to learn that radioactivity exists in people's daily lives and is used safely in various field; (2) to get basic knowledge and better quantitative understanding of such things as radioactivity units, radiation dose and radiation effects; and (3) to acquire practical experience to use the information effectively. (author)

  8. Radiographers' opinions on radiography research in Norway – A national survey

    International Nuclear Information System (INIS)

    Vikestad, K.G.; Hafskjold, L.; Kjelle, E.; Sebuødegård, S.; Hofvind, S.

    2017-01-01

    Objective: The objective of the Norwegian Radiography Research Group is to establish a strategy for radiography research in Norway. A survey investigating radiographers' opinions on research was conducted to establish a basis for this strategy. Methods: A questionnaire was sent to all members of the Norwegian Society of Radiographers using the society's e-mail list from May 2014 (n = 2273). The respondents, 31% (n = 697), were divided into six groups; general radiographers (n = 392), specialised radiographers (n = 124), managers (n = 74), radiation therapists (n = 59), professors (n = 13), and others (n = 35). The questionnaire included four parts: introduction, participation in research, research performed at the respondent's work place, and opinions on radiography research. The first parts consisted of close-ended questions, while the fourth part also included a Likert scale. Results: Among all respondents, 63% respondents agreed that there is a need for radiography research and 50% agreed that general radiographers/radiation therapists should be the principal investigators of such research. However, only 19% reported participation in a research project during the last five years, and of those, 50% knew how the results of their research had been communicated. Conclusion: The majority of radiographers agreed that there was a need for radiography research and that radiographers/radiation therapists should take a leading role in such work. The results indicate that radiographers/radiation therapists would benefit from training in informal and formal research skills. - Highlights: • Two in ten radiographers took part in research activity in Norway. • Six in ten agreed that there is a need for radiographic related research in Norway. • Evidence-based practice, informal and formal research training represent the main aim to reach in the first strategy for radiography research in Norway.

  9. Opinions regarding neonatal resuscitation training for the obstetric physician: a survey of neonatal and obstetric training program directors.

    Science.gov (United States)

    Bruno, C J; Johnston, L; Lee, C; Bernstein, P S; Goffman, D

    2018-04-01

    Our goal was to garner opinions regarding neonatal resuscitation training for obstetric physicians. We sought to evaluate obstacles to neonatal resuscitation training for obstetric physicians and possible solutions for implementation challenges. We distributed a national survey via email to all neonatal-perinatal medicine fellowship directors and obstetrics & gynecology residency program directors in the United States. This survey was designed by a consensus method. Ninety-eight (53%) obstetric and fifty-seven (51%) neonatal program directors responded to our surveys. Eighty-eight percent of neonatologists surveyed believe that obstetricians should be neonatal resuscitation program (NRP) certified. The majority of surveyed obstetricians (>89%) believe that obstetricians should have some neonatal resuscitation training. Eighty-six percent of obstetric residents have completed training in NRP, but only 19% of obstetric attendings are NRP certified. Major barriers to NRP training that were identified include time, lack of national requirement, lack of belief it is helpful, and cost. Most obstetric attendings are not NRP certified, but the majority of respondents believe that obstetric providers should have some neonatal resuscitation training. Our study demonstrates that most respondents support a modified neonatal resuscitation course for obstetric physicians.

  10. 10 points about buying C.I.S

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    On October 16, 1992, the U.S. Department of Commerce (DOC) settled the antidumping case against the CIS republics by imposing price and volume quotas on CIS uranium imported into the United States. Bound by a suspension agreement, each of the six uranium-producing CIS republics is responsible for restricting the flow of imports to the US-either directly or indirectly. (As the NUKEM Market Report went to press, the Ukraine government notified the DOC of its intent not to terminate the suspension agreement.) This action is to prevent undercutting price levels in the US domestic uranium markets. What follows are ten points about everything you should know about importing uranium from the uranium-producing CIS republics- Kazakhstan, Kyrgyzstan, Russian Federation, Tajikistan, Ukraine and Uzbekistan. Newcomers to the CIS scene should follow this simple roadmap and be aware of the issues they face as importers in terms of Commerce/Customs requirements and documentation and where to get them, when to buy the material and how to transport it, how to deal effectively with CIS exporters, and how to avoid unnecessary complications when buying CIS

  11. The Opinions of GP's Patients About Suicide, Assisted Suicide, Euthanasia, and Suicide Prevention: An Italian Survey.

    Science.gov (United States)

    Poma, Stefano Zanone; Vicentini, Silvia; Siviero, Francesca; Grossi, Antonello; Toniolo, Emanuele; Baldo, Vincenzo; De Leo, Diego

    2015-08-01

    A survey about opinions on end-of-life issues of a population represented by 1,171 people in the waiting room of general practitioners' surgeries was conducted in a province of northern Italy. Most subjects did not consider suicide as a reasonable option even in cases of a serious and incurable disease. Moreover, subjects did not consider euthanasia as a possible option either; however, they did express an opposite attitude when considering euthanasia in a third-person perspective. People with a personal history of suicidal behavior appear to present as a different population, overall expressing more open attitudes. © 2014 The American Association of Suicidology.

  12. What drives people's opinions of electricity infrastructure? Empirical evidence from Ireland

    International Nuclear Information System (INIS)

    Bertsch, Valentin; Hyland, Marie; Mahony, Michael

    2017-01-01

    Across the EU, significant infrastructure investment is needed in both generation from renewable energy sources (RES) and the electricity grid to meet the European targets on emission reduction and RES expansion. Experiences show, however, that citizens may object to new energy infrastructure in their localities which may cause delays in achieving the targets. To avoid delays, it is crucial to understand what drives people's opinions. To explore people's opinions of different electricity generation and transmission technologies in Ireland, we conducted a nationally-representative survey. Concerning the drivers, we distinguish between socio-demographics, technology-specific perceptions, and energy policy preferences. Our results show that people generally have positive views of RES technologies. While this indicates that Irish citizens agree to move towards cleaner electricity sources, we find reluctance amongst people to have these technologies located close to their places of residence. We find that, across most technologies, the tradeoff people make between economic and environmental policy objectives drives their opinions of, and their tendencies to oppose, technology developments. The significance of most socio-demographic variables, however, is largely technology-dependent. This highlights that policy makers need to understand how people make tradeoffs between policy objectives and how these tradeoffs relate to their opinions of different technologies. - Highlights: • Conducted a survey to understand drivers of opinions of electricity infrastructure. • Considered socio-demographic, policy-related and technology-specific drivers. • Irish citizens generally have positive opinions of renewable technologies. • Positive opinions don't rule out local opposition. • Tradeoffs on policy objectives shape opinions most consistently across technologies.

  13. Attitudes and Beliefs About Domestic Violence: Results of a Public Opinion Survey. I. Definitions of Domestic Violence, Criminal Domestic Violence, and Prevalence

    Science.gov (United States)

    Carlson, Bonnie E.; Worden, Alissa Pollitz

    2005-01-01

    This study reports analyses and findings from a public opinion survey designed to explore beliefs about domestic violence (DV) -- what it is, when it is against the law, and how prevalent it is. The project interviewed 1,200 residents from six New York communities. The analyses reveal substantial first hand and second hand experience with DV and…

  14. Nuclear power engineering: Public understanding and public opinion

    International Nuclear Information System (INIS)

    Kryshev, A.I.; Sazykina, T.G.

    1998-01-01

    Subjective and objective reasons for the formation of public opinion about nuclear power engineering of Russia were analyzed. Some methodological errors in work with the Russian public on the problems of nuclear energy and possible methods of their correction were discussed. The social groups of the general public, which are of greatest importance in forming the attitude towards nuclear power engineering were indicated. The conclusion was reached that opinion of the ordinary population is often indicative of real drawbacks in the work of specialists in the nuclear fuel cycle. Consequently, careful surveys of public opinion about the problems of the nuclear industry should be very useful in organizing research work properly and improving the radiation safety. (author)

  15. Climate Change and Infectious Disease Risk in Western Europe: A Survey of Dutch Expert Opinion on Adaptation Responses and Actors.

    Science.gov (United States)

    Akin, Su-Mia; Martens, Pim; Huynen, Maud M T E

    2015-08-18

    There is growing evidence of climate change affecting infectious disease risk in Western Europe. The call for effective adaptation to this challenge becomes increasingly stronger. This paper presents the results of a survey exploring Dutch expert perspectives on adaptation responses to climate change impacts on infectious disease risk in Western Europe. Additionally, the survey explores the expert sample's prioritization of mitigation and adaptation, and expert views on the willingness and capacity of relevant actors to respond to climate change. An integrated view on the causation of infectious disease risk is employed, including multiple (climatic and non-climatic) factors. The results show that the experts consider some adaptation responses as relatively more cost-effective, like fostering interagency and community partnerships, or beneficial to health, such as outbreak investigation and response. Expert opinions converge and diverge for different adaptation responses. Regarding the prioritization of mitigation and adaptation responses expert perspectives converge towards a 50/50 budgetary allocation. The experts consider the national government/health authority as the most capable actor to respond to climate change-induced infectious disease risk. Divergence and consensus among expert opinions can influence adaptation policy processes. Further research is necessary to uncover prevailing expert perspectives and their roots, and compare these.

  16. cis-Bifenthrin enantioselectively induces hepatic oxidative stress in mice.

    Science.gov (United States)

    Jin, Yuanxiang; Wang, Jiangcong; Pan, Xiuhong; Wang, Linggang; Fu, Zhengwei

    2013-09-01

    Bifenthrin (BF), as a chiral synthetic pyrethroid, is widely used to control field and household pests. In China, the commercial cis-BF contained two enantiomers including 1R-cis-BF and 1S-cis-BF. However, the difference in oxidative stress induced by the two enantiomers in mice still remains unclear. In the present study, 4 week-old adolescent male ICR mice were orally administered cis-BF, 1R-cis-BF or 1S-cis-BF daily for 2, 4 and 6 weeks at doses of 5 mg/kg/day, respectively. We found that the hepatic reactive oxygen species (ROS) levels, as well as the malondialdehyde (MDA) and glutathione (GSH) content both in the serum and liver increased significantly in the 4 or 6 weeks 1S-cis-BF treated groups. The activities of superoxide dismutase (SOD) and catalase (CAT) also changed significantly in the serum and liver of 1S-cis-BF treated mice. More importantly, the significant differences in MDA content and CAT activity both in the serum and liver, and the activities of total antioxidant capacity (T-AOC) and SOD in serum were also observed between the 1S-cis-BF and 1R-cis-BF treated groups. Moreover, the transcription of oxidative stress response related genes including Sod1, Cat and heme oxygenase-1(Ho-1) in the liver of 1S-cis-BF treated groups were also significant higher than those in 1R-cis-BF treated group. Thus, it was concluded that cis-BF induced hepatic oxidative stress in an enantiomer specific manner in mice when exposed during the puberty, and that 1S-cis-BF showed much more toxic in hepatic oxidative stress than 1R-cis-BF. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. CisLunar Habitat Internal Architecture Design Criteria

    Science.gov (United States)

    Jones, R.; Kennedy, K.; Howard, R.; Whitmore, M.; Martin, C.; Garate, J.

    2017-01-01

    BACKGROUND: In preparation for human exploration to Mars, there is a need to define the development and test program that will validate deep space operations and systems. In that context, a Proving Grounds CisLunar habitat spacecraft is being defined as the next step towards this goal. This spacecraft will operate differently from the ISS or other spacecraft in human history. The performance envelope of this spacecraft (mass, volume, power, specifications, etc.) is being defined by the Future Capabilities Study Team. This team has recognized the need for a human-centered approach for the internal architecture of this spacecraft and has commissioned a CisLunar Phase-1 Habitat Internal Architecture Study Team to develop a NASA reference configuration, providing the Agency with a "smart buyer" approach for future acquisition. THE CISLUNAR HABITAT INTERNAL ARCHITECTURE STUDY: Overall, the CisLunar Habitat Internal Architecture study will address the most significant questions and risks in the current CisLunar architecture, habitation, and operations concept development. This effort is achieved through definition of design criteria, evaluation criteria and process, design of the CisLunar Habitat Phase-1 internal architecture, and the development and fabrication of internal architecture concepts combined with rigorous and methodical Human-in-the-Loop (HITL) evaluations and testing of the conceptual innovations in a controlled test environment. The vision of the CisLunar Habitat Internal Architecture Study is to design, build, and test a CisLunar Phase-1 Habitat Internal Architecture that will be used for habitation (e.g. habitability and human factors) evaluations. The evaluations will mature CisLunar habitat evaluation tools, guidelines, and standards, and will interface with other projects such as the Advanced Exploration Systems (AES) Program integrated Power, Avionics, Software (iPAS), and Logistics for integrated human-in-the-loop testing. The mission of the Cis

  18. Eliciting expert opinion for economic models: an applied example.

    Science.gov (United States)

    Leal, José; Wordsworth, Sarah; Legood, Rosa; Blair, Edward

    2007-01-01

    Expert opinion is considered as a legitimate source of information for decision-analytic modeling where required data are unavailable. Our objective was to develop a practical computer-based tool for eliciting expert opinion about the shape of the uncertainty distribution around individual model parameters. We first developed a prepilot survey with departmental colleagues to test a number of alternative approaches to eliciting opinions on the shape of the uncertainty distribution around individual parameters. This information was used to develop a survey instrument for an applied clinical example. This involved eliciting opinions from experts to inform a number of parameters involving Bernoulli processes in an economic model evaluating DNA testing for families with a genetic disease, hypertrophic cardiomyopathy. The experts were cardiologists, clinical geneticists, and laboratory scientists working with cardiomyopathy patient populations and DNA testing. Our initial prepilot work suggested that the more complex elicitation techniques advocated in the literature were difficult to use in practice. In contrast, our approach achieved a reasonable response rate (50%), provided logical answers, and was generally rated as easy to use by respondents. The computer software user interface permitted graphical feedback throughout the elicitation process. The distributions obtained were incorporated into the model, enabling the use of probabilistic sensitivity analysis. There is clearly a gap in the literature between theoretical elicitation techniques and tools that can be used in applied decision-analytic models. The results of this methodological study are potentially valuable for other decision analysts deriving expert opinion.

  19. Public opinion factors regarding nuclear power

    Energy Technology Data Exchange (ETDEWEB)

    Benson, B.

    1991-12-31

    This paper is an effort to identify, as comprehensively as possible, public concerns about nuclear power, and to assess, where possible, the relative importance of these concerns as they relate to government regulation of and policy towards nuclear power. It is based on some two dozen in-depth interviews with key communicators representing the nuclear power industry, the environmental community, and government, as well as on the parallel efforts in our research project: (1) review of federal court case law, (2) a selective examination of the Nuclear Regulatory Commission (NRC) administrative process, and (3) the preceding George Mason University research project in this series. The paper synthesizes our findings about public attitudes towards nuclear power as expressed through federal court case law, NRC administrative law, public opinion surveys, and direct personal interviews. In so doing, we describe the public opinion environment in which the nuclear regulatory process must operate. Our premise is that public opinion ultimately underlies the approaches government agencies take towards regulating nuclear power, and that, to the degree that the nuclear power industry`s practices are aligned with public opinion, a more favorable regulatory climate is possible.

  20. Public opinion factors regarding nuclear power

    Energy Technology Data Exchange (ETDEWEB)

    Benson, B.

    1991-01-01

    This paper is an effort to identify, as comprehensively as possible, public concerns about nuclear power, and to assess, where possible, the relative importance of these concerns as they relate to government regulation of and policy towards nuclear power. It is based on some two dozen in-depth interviews with key communicators representing the nuclear power industry, the environmental community, and government, as well as on the parallel efforts in our research project: (1) review of federal court case law, (2) a selective examination of the Nuclear Regulatory Commission (NRC) administrative process, and (3) the preceding George Mason University research project in this series. The paper synthesizes our findings about public attitudes towards nuclear power as expressed through federal court case law, NRC administrative law, public opinion surveys, and direct personal interviews. In so doing, we describe the public opinion environment in which the nuclear regulatory process must operate. Our premise is that public opinion ultimately underlies the approaches government agencies take towards regulating nuclear power, and that, to the degree that the nuclear power industry's practices are aligned with public opinion, a more favorable regulatory climate is possible.

  1. Public opinion factors regarding nuclear power

    International Nuclear Information System (INIS)

    Benson, B.

    1991-01-01

    This paper is an effort to identify, as comprehensively as possible, public concerns about nuclear power, and to assess, where possible, the relative importance of these concerns as they relate to government regulation of and policy towards nuclear power. It is based on some two dozen in-depth interviews with key communicators representing the nuclear power industry, the environmental community, and government, as well as on the parallel efforts in our research project: (1) review of federal court case law, (2) a selective examination of the Nuclear Regulatory Commission (NRC) administrative process, and (3) the preceding George Mason University research project in this series. The paper synthesizes our findings about public attitudes towards nuclear power as expressed through federal court case law, NRC administrative law, public opinion surveys, and direct personal interviews. In so doing, we describe the public opinion environment in which the nuclear regulatory process must operate. Our premise is that public opinion ultimately underlies the approaches government agencies take towards regulating nuclear power, and that, to the degree that the nuclear power industry's practices are aligned with public opinion, a more favorable regulatory climate is possible

  2. Fertility treatment for the transgender community: a public opinion study.

    Science.gov (United States)

    Goldman, Randi H; Kaser, Daniel J; Missmer, Stacey A; Farland, Leslie V; Scout; Ashby, Rachel K; Ginsburg, Elizabeth S

    2017-11-01

    The purposes of this study were to evaluate public opinion regarding fertility treatment and gamete cryopreservation for transgender individuals and identify how support varies by demographic characteristics. This is a cross-sectional web-based survey study completed by a representative sample of 1111 US residents aged 18-75 years. Logistic regression was used to calculate odd ratios (ORs) and 95% confidence intervals (CIs) of support for/opposition to fertility treatments for transgender people by demographic characteristics, adjusting a priori for age, gender, race, and having a biological child. Of 1336 people recruited, 1111 (83.2%) agreed to participate, and 986 (88.7%) completed the survey. Most respondents (76.2%) agreed that "Doctors should be able to help transgender people have biological children." Atheists/agnostics were more likely to be in support (88.5%) than Christian-Protestants (72.4%; OR = 3.10, CI = 1.37-7.02), as were younger respondents, sexual minorities, those divorced/widowed, Democrats, and non-parents. Respondents who did not know a gay person (10.0%; OR = 0.20, CI = 0.09-0.42) or only knew a gay person without children (41.4%; OR = 0.29, CI = 0.17-0.50) were more often opposed than those who knew a gay parent (48.7%). No differences in gender, geography, education, or income were observed. A smaller majority of respondents supported doctors helping transgender minors preserve gametes before transitioning (60.6%) or helping transgender men carry pregnancies (60.1%). Most respondents who support assisted and third-party reproduction also support such interventions to help transgender people have children.

  3. Dilemmas of compliance in the CIS

    International Nuclear Information System (INIS)

    Vorobyev, A.

    1996-01-01

    The objective of this paper is to examine some of the difficulties faced by Russia and other Common Independent States (CIS) in the field of compliance with disarmament treaties and non-proliferation regimes, as well as ways and means, particularly with regard to the legal framework, designed to overcome these difficulties. Naturally, the fate and pace of overcoming the existing problems will depend only partially on development of CIS States. A large variety of international factors and the general security will be essential for progress in resolving disarmament and arms control issues in the CIS

  4. Measuring and Understanding Public Opinion on Human Evolution

    Science.gov (United States)

    Gwon, Misook

    The theory of evolution has long generated controversy in American society, but Americans' attitudes about human evolution are often neglected in studies of "culture wars" and the nature of mass belief systems more generally (Berkman and Plutzer 2010; Freeland and Houston 2009). Gallup and other survey organizations have polled about evolution, but offered limited response categories that mask complexity in public opinion (Bishop 2006; Moore 2008). The main problems concerning the leading survey questions about evolution are: first, questions measure only a single dimension, thus they ignore the potential for multidimensionality in people's attitudes. Second, depending on question wording and response options, the results of public opinion surveys vary by polling groups. This is an example of measurement error which misleads the interpretation and impression of American public opinion on the origin of humankind. A number of studies have analyzed Americans' beliefs about evolution and hypothesized about the influential effects of several factors (Deckman 2002; Mazur 2005; Mooney 2005; Miller et al. 2006; Newport 2006; Forrest 2007;Nisbet and Goidel 2007;Scott 2009). However, there remains a lack of complete understanding of what Americans know and believe about human evolution. Given the salience of this issue and the significant influence of public opinion on policy-making in America (Page and Shapiro 1992; Stimson 2004; Newport 2004), the measurement error and explanation of polling results on controversial issues related to this topic are in need of clarification. In this study, I address these deficiencies with analyses of data from a 2008 national survey by Harris Interactive (n= 4,626) that included numerous measures of factual knowledge and beliefs about evolution. The items offer more nuanced response options than the standard three-category question asked for decades by the Gallup poll. The Harris survey also had multiple measures of religiosity and the

  5. French hospital nurses' opinion about euthanasia and physician-assisted suicide: a national phone survey.

    Science.gov (United States)

    Bendiane, M K; Bouhnik, A-D; Galinier, A; Favre, R; Obadia, Y; Peretti-Watel, P

    2009-04-01

    Hospital nurses are frequently the first care givers to receive a patient's request for euthanasia or physician-assisted suicide (PAS). In France, there is no consensus over which medical practices should be considered euthanasia, and this lack of consensus blurred the debate about euthanasia and PAS legalisation. This study aimed to investigate French hospital nurses' opinions towards both legalisations, including personal conceptions of euthanasia and working conditions and organisation. A phone survey conducted among a random national sample of 1502 French hospital nurses. We studied factors associated with opinions towards euthanasia and PAS, including contextual factors related to hospital units with random-effects logistic models. Overall, 48% of nurses supported legalisation of euthanasia and 29%, of PAS. Religiosity, training in pallative care/pain management and feeling competent in end-of-life care were negatively correlated with support for legalisation of both euthanasia and PAS, while nurses working at night were more prone to support legalisation of both. The support for legalisation of euthanasia and PAS was also weaker in pain treatment/palliative care and intensive care units, and it was stronger in units not benefiting from interventions of charity/religious workers and in units with more nurses. Many French hospital nurses uphold the legalisation of euthanasia and PAS, but these nurses may be the least likely to perform what proponents of legalisation call "good" euthanasia. Improving professional knowledge of palliative care could improve the management of end-of-life situations and help to clarify the debate over euthanasia.

  6. OpinionFlow: Visual Analysis of Opinion Diffusion on Social Media.

    Science.gov (United States)

    Wu, Yingcai; Liu, Shixia; Yan, Kai; Liu, Mengchen; Wu, Fangzhao

    2014-12-01

    It is important for many different applications such as government and business intelligence to analyze and explore the diffusion of public opinions on social media. However, the rapid propagation and great diversity of public opinions on social media pose great challenges to effective analysis of opinion diffusion. In this paper, we introduce a visual analysis system called OpinionFlow to empower analysts to detect opinion propagation patterns and glean insights. Inspired by the information diffusion model and the theory of selective exposure, we develop an opinion diffusion model to approximate opinion propagation among Twitter users. Accordingly, we design an opinion flow visualization that combines a Sankey graph with a tailored density map in one view to visually convey diffusion of opinions among many users. A stacked tree is used to allow analysts to select topics of interest at different levels. The stacked tree is synchronized with the opinion flow visualization to help users examine and compare diffusion patterns across topics. Experiments and case studies on Twitter data demonstrate the effectiveness and usability of OpinionFlow.

  7. Psychiatric Opinion and Homosexuality: A Short Report

    Science.gov (United States)

    Barr, R. F.; And Others

    1975-01-01

    In a survey of opinion among 100 psychiatrists and 93 trainees in Australia, the majority endorsed the view either that "homosexuality is a developmental anomaly not necessarily or commonly associated with neurotic symptoms" or that "homosexuality is a normal variant like left-handedness." (Author)

  8. Up front in the CIS

    International Nuclear Information System (INIS)

    Grey, C.A.

    1994-01-01

    A picture is drawn of the current supply side of the front-end fuel cycle production capacities in the CIS. Uranium production has been steadily declining, as in the West. Market realities have been reflected in local costs of production since the break-up of the former Soviet Union and some uneconomic mines have been closed. In terms of actual production, Kazakhstan, Russia and Uzbekistan, remain among the top five uranium producers in the world. Western government action has been taken to restrict the market access for natural uranium from the CIS. Reactors in the CIS continue to be supplied with fabricated fuel solely by Russian, though Western fuel fabricators have reduced Russian supplies to Eastern Europe. Russia's current dominance in conversion and enrichment services in both the CIS and Eastern Europe is likely to continue as long as the present surplus low enriched uranium stocks last and surplus production capacity exists. Market penetration in the West has been limited by government action but Russia in 1993 still held about 20% of the world's conversion market and nearly 19% of the enrichment market. (6 figures, 2 tables, 4 references) (UK)

  9. Knowledge and Opinion on the Nuclear Freeze: A Test of Three Models.

    Science.gov (United States)

    Tankard, James W., Jr.

    To explore how knowledge influences opinion in foreign policy, results of a survey on voter familiarity with and attitude toward nuclear policy issues were compared with three theoretical models of the knowledge/opinion relationship: (1) the enlightenment model--as knowledge increases, support for belligerent foreign policy stands decreases; (2)…

  10. The public opinion and ATC; La opinion publica y el ATC

    Energy Technology Data Exchange (ETDEWEB)

    Ballera, J.

    2010-07-01

    The role of the media is essential to adopt a final decision in relation to the location of a Centralized Temporary Storage (ATC)in Spain. to the deliberative process is public, open and transparent, as included in Royal Decree that created the Inter ministerial Commission responsible for overseeing the procedure, it is necessary for that citizens has information, clear and unequivocal. indicators such as the special edition of the Eurobarometer survey published in June 2008 showed that it is moving towards a truly informed public opinion in these matters. (Author)

  11. Public opinion about energy: a literature review

    Energy Technology Data Exchange (ETDEWEB)

    Farhar, B.C.; Weis, P.; Unseld, C.T.; Burns, B.A.

    1979-06-01

    A review and analysis of 115 surveys of the general population between 1973 and 1978 (before the Three Mile Island accident, sudden gasoline price increases, and spot gasoline shortages) are presented. The survey data are organized and analyzed according to a set of categories described in Chapter 2. The public's definition of the energy situation is the focus of Chapter 3. Chapter 4 describes public opinion concerning energy conservation pertaining to transportation and domestic energy use -- whether it is efficacious, how knowledgeable people are about conservation, whether they favor it, and whether they engage in it. Findings on the solar energy alternative are described in Chapter 5. Public opinion concerning more conventional sources of energy -- oil and natural gas, coal, and nuclear energy -- are discussed in Chapter 6. In Chapter 7, a summary of analytical findings by 10 major sociodemographic characteristics is presented. Chapter 8 describes analytical findings using various social-psychological variables. A summary is presented in Chapter 9.

  12. cisMEP: an integrated repository of genomic epigenetic profiles and cis-regulatory modules in Drosophila.

    Science.gov (United States)

    Yang, Tzu-Hsien; Wang, Chung-Ching; Hung, Po-Cheng; Wu, Wei-Sheng

    2014-01-01

    Cis-regulatory modules (CRMs), or the DNA sequences required for regulating gene expression, play the central role in biological researches on transcriptional regulation in metazoan species. Nowadays, the systematic understanding of CRMs still mainly resorts to computational methods due to the time-consuming and small-scale nature of experimental methods. But the accuracy and reliability of different CRM prediction tools are still unclear. Without comparative cross-analysis of the results and combinatorial consideration with extra experimental information, there is no easy way to assess the confidence of the predicted CRMs. This limits the genome-wide understanding of CRMs. It is known that transcription factor binding and epigenetic profiles tend to determine functions of CRMs in gene transcriptional regulation. Thus integration of the genome-wide epigenetic profiles with systematically predicted CRMs can greatly help researchers evaluate and decipher the prediction confidence and possible transcriptional regulatory functions of these potential CRMs. However, these data are still fragmentary in the literatures. Here we performed the computational genome-wide screening for potential CRMs using different prediction tools and constructed the pioneer database, cisMEP (cis-regulatory module epigenetic profile database), to integrate these computationally identified CRMs with genomic epigenetic profile data. cisMEP collects the literature-curated TFBS location data and nine genres of epigenetic data for assessing the confidence of these potential CRMs and deciphering the possible CRM functionality. cisMEP aims to provide a user-friendly interface for researchers to assess the confidence of different potential CRMs and to understand the functions of CRMs through experimentally-identified epigenetic profiles. The deposited potential CRMs and experimental epigenetic profiles for confidence assessment provide experimentally testable hypotheses for the molecular mechanisms

  13. Physical activity and associated factors among young adults in Malaysia: an online exploratory survey.

    Science.gov (United States)

    Sreeramareddy, C T; Majeed Kutty, N A; Razzaq Jabbar, M A; Boo, N Y

    2012-06-01

    The burden of non-communicable diseases is increasing in Malaysia. Insufficient Physical Activity, which is an important risk factor for non-communicable diseases, is less researched in Malaysia. We aimed to assess the level of physical activity and identify its correlates. An online survey was carried out during October, 2011 in the University Tunku Abdul Rahman by the opinion poll research committee. Young adults answered the Short International Physical Activity Questionnaire and a questionnaire about factors according to a socio-ecological model which was adapted from published studies. Metabolic equivalent (MET)-hours and MET-minutes were calculated. Physical activity was classified as sufficient when MET-minutes were > 840. The mean age of the 474 participants was 22.4 years (S.D. = 4.7), and 253 (53.4%) were females. Their mean and median of MET-hours of PA done during the previous seven days were 31.36 (S.D., 52.19) and 14.7 (IQR, 5.77-32.07), respectively. Physical activity done was sufficient among 242 (51.1%) participants. Using univariate analysis, being male, good self-rated health, positive intention, self-efficacy, perceived benefits, social support, and availability of facilities were associated with sufficient physical activity. Using multivariate analysis sufficient physical activity was associated with participants' intention (OR 0.75, 95% CIs 0.64, 0.88), self-efficacy (OR 0.91, 95% CIs 0.85, 0.97) and facility availability (OR 0.81, 95% CIs 0.73, 0.91). The proportion of participants with sufficient physical activity was low. Positive intention and self-efficacy associated with sufficient physical activity should be supported by availability of facilities and a safely-built environment. A nationwide survey about physical and associated socialecological factors is needed to design rational health promotion strategies.

  14. Health care issues in Croatian elections 2005-2010: series of public opinion surveys.

    Science.gov (United States)

    Radin, Dagmar; Dzakula, Aleksandar; Benkovic, Vanesa

    2011-10-15

    To compare the results of a series of public opinion surveys on experiences with the health care sector in Croatia conducted in the time of elections and to analyze whether political party affiliation had any influence on issues of priority ranking. The surveys were conducted during 2005, 2007, and 2009. They were administered through a Computer Assisted Telephone Interviewing method to representative samples of Croatian population and were statistically weighted according to sex, age, level of education, and political party affiliation. The random sampling of the person within the household was done using the table of random numbers. Health and health care system was the most important issue (58%) during the 2007 parliamentary election and the second most important issue during the 2005 and 2009 elections (46% and 28%). In the 2007 election, health care was viewed as most important by women, respondents with lower education levels, and respondents with lower income. In 2005, the most important health care issues were corruption and lack of funding (45% and 43%, respectively), in 2007 poor organization and lack of funding (43% and 42%, respectively), and in 2009 lack of funding and corruption (51% and 45%, respectively). Health and health care system were consistently among the top two issues in all elections from 2005 to 2009. The top three most important health care sector issues were corruption, poor organization, and lack of funding. This indicates that political parties should include solutions to these issues in their health care policymaking.

  15. Prioritizing Approaches to Engage Community Members and Build Trust in Biobanks: A Survey of Attitudes and Opinions of Adults within Outpatient Practices at the University of Maryland

    Directory of Open Access Journals (Sweden)

    Casey Lynnette Overby

    2015-07-01

    Full Text Available Background: Achieving high participation of communities representative of all sub-populations is needed in order to ensure broad applicability of biobank study findings. This study aimed to understand potentially mutable attitudes and opinions commonly correlated with biobank participation in order to inform approaches to promote participation in biobanks. Methods: Adults from two University of Maryland (UMD Faculty Physicians, Inc. outpatient practices were invited to watch a video and complete a survey about a new biobank initiative. We used: Chi-square to assess the relationship between willingness to join the biobank and participant characteristics, other potentially mutable attitudes and opinions, and trust in the UMD. We also used t-test to assess the relationship with trust in medical research. We also prioritize proposed actions to improve attitudes and opinions about joining biobanks according to perceived responsiveness. Results: 169 participants completed the study, 51% of whom indicated a willingness to join the biobank. Willingness to join the biobank was not associated with age, gender, race, or education but was associated with respondent comfort sharing samples and clinical information, concerns related to confidentiality, potential for misuse of information, trust in UMD, and perceived health benefit. In ranked order, potential actions we surveyed that might alleviate some of these concerns include: increase chances to learn more about the biobank, increase opportunities to be updated, striving to put community concerns first, including involving community members as leaders of biobank research, and involving community members in decision making. Conclusions: This study identified several attitudes and opinions that influence decisions to join a biobank, including many concerns that could potentially be addressed by engaging community members. We also demonstrate our method of prioritizing ways to improve attitudes and opinions

  16. Opinions and Knowledge About Climate Change Science in High School Students

    DEFF Research Database (Denmark)

    Harker-Schuch, Inez; Henriksen, Christian Bugge

    2013-01-01

    in national and international schools before and after a lecture in climate change science. The results show that knowledge about climate change science significantly affects opinions about climate change. Students with a higher number of correct answers are more likely to have the opinion that humans......This study investigates the influence of knowledge on opinions about climate change in the emerging adults' age group (16-17 years). Furthermore, the effects of a lecture in climate change science on knowledge and opinions were assessed. A survey was conducted in Austria and Denmark on 188 students...... are causing climate change and that both individuals and governments are responsible for addressing climate change. The lecture in climate change science significantly improved knowledge development but did not affect opinions. Knowledge was improved by 11 % after the lecture. However, the percentage...

  17. Opinion, energy and climate

    International Nuclear Information System (INIS)

    2009-02-01

    The author comments the evolution of the results of various opinion surveys on energy in France and more particularly the high support for electricity production from renewable energies, the acceptance of the financial burden associated to energy, the fact that nuclear energy has more benefits than pitfalls but is still considered as a hazardous activity, the fact that consumers are aware of environmental risks for the planet but still have an incomplete knowledge of the energy sector and new technologies

  18. Problems and Proposals of Their Solutions in Dermatology Residency Training: A Survey of Residents’ Opinions in Turkey

    Directory of Open Access Journals (Sweden)

    Sadık Yılmaz

    2009-03-01

    Full Text Available Background and Design: There are many problems in dermatology residency training. The purpose of this study was to describe dermatology residents’ opinions about problems and proposals of their solutions of dermatology residency training programs in Turkey. In addition, by means of these estimations to propose efficient and standard curriculum components are aimed. Material and Method: A descriptive pilot study was designed and a questionnaire was prepared to describe the problems and suggestions for the solution in dermatology residency education. The survey was conducted between 20 June 2006 and 09 August 2006. The questions were prepared in accordance with a 1 to 5 Likert-type scale to evaluate the level of importance and sufficiency of the residents’ opinions. Results: Sixty seven (52 female, 15 male residents responded to the survey. Based on the importance evaluation, although clinical-pathological meetings were the most important educational component, all other educational components were also indicated as important. Based on the sufficiency evaluation, the least sufficient educational components were photodermatology/laser therapy training (score, 1,82 of 5,0 and cosmetic dermatology (1,83. Sufficiency levels of educational components such as textbook review, translation and discussion (3,86 journal club (4,04, preparation of seminar (4,03 and allergy training (2,95 were evaluated as sufficient. All other educational components were determined as insufficient. Overall, the greatest discrepancies between the importance and sufficiency for all educational components were observed in cosmetic dermatology education (2,50.Conclusion: This is the first study to assess dermatology residency education based on the residents’ perspectives, in Turkey. These results show the necessity for review and revise of some of the elements and the necessity to prepare a standard curriculum of dermatology residency education. It is appropriate to

  19. Public opinion and nuclear power decision-making

    International Nuclear Information System (INIS)

    Benson, B.

    1991-01-01

    This document discusses public opinion regarding nuclear power which is particularly difficult to tie down because of five important paradoxes that characterize it: it can be based on sound reason, but also on intense emotion; it is both national and local in perspective; at varying times it has seen nuclear power as both ''clean'' and ''dirty''; it believes nuclear power is both economic, and uneconomic; and nuclear power is perceived as having a fairly safe record, but being potentially unsafe. Equally as complex as the process by which public opinion is formed is the process by which it is converted into public policy. The American political system has numerous checks and balances designed to moderate the power of public opinion. A complex series of legislative, judicial, and executive branch hurdles must be cleared before any idea, however popular, can become day-to-day operating reality in government. As a result, major changes in policy or programs are difficult, and we may expect that nuclear power will be no different; radical change in one direction or the other is unlikely. Nevertheless, carefully focused programs could achieve modest progress, and carefully designed public opinion surveys could support such programs

  20. Ready access to functionally embellished cis-hydrindanes and cis-decalins: protecting group-free total syntheses of (±)-Nootkatone and (±)-Noreremophilane.

    Science.gov (United States)

    Handore, Kishor L; Seetharamsingh, B; Reddy, D Srinivasa

    2013-08-16

    A simple and efficient synthesis of functionalized cis-hydrindanes and cis-decalins was achieved using a sequential Diels-Alder/aldol approach in a highly diastereoselective manner. The scope of this method was tested with a variety of substrates and was successfully applied to the synthesis of two natural products in racemic form. The highlights of the present work provide ready access to 13 new cis-hydrindanes/cis-decalins, a protecting group-free total synthesis of an insect repellent Nootkatone, and the first synthesis of a Noreremophilane using the shortest sequence.

  1. ADVENTURE TOURISM IN THE SURVEYED POLISH ADVENTURE TOURISTS’ OPINION – OUTLINE OF THE PROBLEM

    Directory of Open Access Journals (Sweden)

    Ewa Cieślik

    2014-12-01

    Full Text Available Tourism is a kind of human activity, which has the ability to simultaneously satisfy a wide human needs’ range and develop people’s personality. Adventure tourism term is a type of tourism able to fulfill these types of human needs. The aim of the study was to know the Polish tourists opinion about the adventure tourism in Poland. The study involved 50 people, taking into account their gender, age, education and occupational status. The research tool was a survey questionnaire. The study indicated that it is not a popular form of tourism in Poland. Its proponents, the information about places and facilities derive mainly from the Internet. The most popular forms are trekking, tramping, caves exploration, paintball, windsurfing, bungejumping and rafting. Rather average possibility of practicing the adventure tourism in Poland is associated with multitude barriers, mainly financial investments, lack of free time, as well as fear and general fear of some of its forms.

  2. Optimization of Pseudomonas putida KT2440 as host for the production of cis, cis-muconate from benzoate

    NARCIS (Netherlands)

    Duuren, van J.B.J.H.

    2011-01-01

    Optimization of Pseudomonas putida KT2440 as host for the production of cis, cis-muconate

    from benzoate P. putida KT2440 was used as biocatalyst given its versatile and energetically robust metabolism.

    Therefore, a mutant was generated and a process developed based on which a

  3. Opinion barometer on energy and climate in January 2009

    International Nuclear Information System (INIS)

    2009-04-01

    This article reports and comments the results of a survey performed by the CREDOC on a representative sample of 2006 French people. Eight questions have been asked, dealing with two main themes: energy production (opinion about the energy production mode, about renewable energies, about nuclear energy) and consumers' attitude (in front of energy price increase, when acquiring expensive equipment like a car, a heater or any other big domestic equipment). Tables give results on the opinion on energy public policy in France, on wind turbine installation. These results are given in terms of gender, age, socio-economic categories, and town size. Graphs indicate the evolution since 1983 of the opinion on nuclear energy and on the worry of nuclear plant incident

  4. Nominal Anchors in the CIS

    OpenAIRE

    Peter M Keller; Thomas J Richardson

    2003-01-01

    Monetary policy has become increasingly important in the countries of the Commonwealth of Independent States (CIS) as fiscal adjustment and structural reforms have taken root. Inflation has been brought down to relatively low levels in almost all of these countries, raising the question of what should be the appropriate nominal anchor at this stage. Formally, almost all CIS countries have floating exchange rate regimes, yet in practice they manage their exchange rates very heavily, perhaps be...

  5. Analysis of Public Opinion Survey ''Nuclear Energy - the Present and the Future'' (2000-2012)

    International Nuclear Information System (INIS)

    Jakic, Irena; Filipin, Renato

    2014-01-01

    Technical Museum Zagreb, in co-operation with Hrvatska elektroprivreda, has been organizing high-school students' visits to the nuclear power plant Krsko since 1989. From schools that have visited the nuclear power plant so far, Zagreb high schools and technical schools are the most represented ones. They filled in the copies of questionnaire after watching film about nuclear energy and before visiting nuclear power plant Krsko. The copies of the public opinion survey (questionnaire) have been filled since 2000 and results of analysis of data until 2012 are in this paper. Questions were the same and that makes possible comparison of the results. (authors)

  6. Novel 9-cis/all-trans β-carotene isomerases from plastidic oil bodies in Dunaliella bardawil catalyze the conversion of all-trans to 9-cis β-carotene.

    Science.gov (United States)

    Davidi, Lital; Pick, Uri

    2017-06-01

    We identified and demonstrated the function of 9-cis/all-trans β-carotene isomerases in plastidic globules of Dunaliella bardawil, the species accumulating the highest levels of 9-cis β-carotene that is essential for humans. The halotolerant alga Dunaliella bardawil is unique in that it accumulates under light stress high levels of β-carotene in plastidic lipid globules. The pigment is composed of two major isomers: all-trans β-carotene, the common natural form of this pigment, and 9-cis β-carotene. The biosynthetic pathway of β-carotene is known, but it is not clear how the 9-cis isomer is formed. We identified in plastidic lipid globules that were isolated from D. bardawil two proteins with high sequence homology to the D27 protein-a 9-cis/all-trans β-carotene isomerase from rice (Alder et al. Science 335:1348-1351, 2012). The proteins are enriched in the oil globules by 6- to 17-fold compared to chloroplast proteins. The expression of the corresponding genes, 9-cis-βC-iso1 and 9-cis-βC-iso2, is enhanced under light stress. The synthetic proteins catalyze in vitro conversion of all-trans to 9-cis β-carotene. Expression of the 9-cis-βC-iso1 or of 9-cis-βC-iso2 genes in an E. coli mutant line that harbors β-carotene biosynthesis genes enhanced the conversion of all-trans into 9-cis β-carotene. These results suggest that 9-cis-βC-ISO1 and 9-cis-βC-ISO2 proteins are responsible for the formation of 9-cis β-carotene in D. bardawil under stress conditions.

  7. Studies on radiosensitization of Escherichia coli cells by cis-platinum complexes

    International Nuclear Information System (INIS)

    Zimbrick, J.D.; Sukrochana, A.; Richmond, R.C.

    1979-01-01

    We recently reported that the antitumor drug cis-Pt(NH 3 ) 2 Cl 2 (cis-DDP) produces significant radiosensitization of anoxic E coli C cells. We have extended these studies to three other platinum drugs, all of which have been shown to be more effective antitumor drugs than cis-DDP. The drugs are: cis-dichloro bis(ethylene imine) Pt(II) (cis-DEP); cis-dichlorobicyclopentylamine Pt(II) (cis-PAD); and Pt-thymine blue (cis-PTB). Survival curve studies indicate that these drugs all produce greater anoxic radiosensitization of E coli C than cis-DDP at concentrations which are less toxic to the cells than similar concentrations of cis-DDP. If the cells are treated with any one of these drugs for two hours and then washed to remove the drug before irradiation, no detectable radiosensitization is found. We conclude that these drugs have the potential for being useful agents in combined modality therapy and that they warrant further study in mammalian systems

  8. Public opinion on Fukushima Daiichi nuclear disaster

    International Nuclear Information System (INIS)

    Hirose, Hirotada

    2013-01-01

    This article showed trend of public opinion on nuclear power after Fukushima Daiichi nuclear disaster, for which the survey had been done five times under the same method and inquiries. Most unreliable source of information at disaster was government ministries and offices, whose unreliability sharply increased from 20% to about 50% after 3 months later and one year later after March 11 and reliability after 2 year and 5 months later (August 2013) was not high and almost comparable with unreliability of 27%. Nuclear disaster was most serious cause of Great East Japan earthquake disaster (60%) and not entirely ended due to such increase of contaminated water. Public opinion survey in August 2013 showed nuclear power stoppage totaled about 80% with immediate of about 30% and phaseout of about 50%, and possibility of occurrence of another nuclear accident comparable with Fukushima disaster was almost 80% with a belief not only earthquakes, tsunamis, terrorism but also human errors might initiate nuclear disaster if nuclear power restarted. Future most serious disaster would be earthquake (50%) and nuclear disaster (35%). Nuclear accident preparedness of government and local government was not enough (58% and 24%) and nothing (33% and 24%). Residents within UPZ (Urgent Protection action Planning Zone) of 30 km radius could not evacuate safely (57%) and entirely (22%). If government and local government encouraged damaged residents to come home with declaration of safety for evacuation area of nuclear accident, damaged residents might not return almost (46%) and entirely (9%). Notwithstanding people's strong feeling against nuclear power, LDP (Liberal Democratic Party) promoting nuclear power won an overwhelming victory at the election of House of Councilors in July 2013. Public opinion survey in August 2013 showed most important issue of voters was party's image (25%), economic measures (20%) and candidate's personality (13%), and nuclear power policy was only 5%. (T

  9. Differing professional views or opinions: 1994 Special Review Panel

    International Nuclear Information System (INIS)

    1996-09-01

    In July 1994, the Executive Director for Operations of the US Nuclear Regulatory Commission (NRC) appointed a Special Review Panel to assess the Differing Professional View or Opinion (DPV/DPO) process, including its effectiveness, how well it is understood by employees, and the organizational climate for having such views aired and properly decided. An additional area within this review was to address the effectiveness of the DPO procedures as they pertain to public access and confidentiality. Further, the Panel was charged with the review of the submittals completed since the last review to identify employees who made significant contributions to the agency or to the public health and safety but had not been adequately recognized for this contribution. The report presents the Special Review Panel's evaluation of the NRC's current process for dealing with Differing Professional Views or Opinions. Provided in this report are the results of an employee opinion survey on the process; highlights and suggestions from interviews with individuals who had submitted a Differing Professional View or Opinion, as well as with agency managers directly involved with the Differing Professional Views or Opinions process; and the Special Review Panel's recommendations for improving the DPV/DPO process

  10. Health care issues in Croatian elections 2005-2009: series of public opinion surveys

    Science.gov (United States)

    Radin, Dagmar; Džakula, Aleksandar; Benković, Vanesa

    2011-01-01

    Aim To compare the results of a series of public opinion surveys on experiences with the health care sector in Croatia conducted in the time of elections and to analyze whether political party affiliation had any influence on issues of priority ranking. Methods The surveys were conducted during 2005, 2007, and 2009. They were administered through a Computer Assisted Telephone Interviewing method to representative samples of Croatian population and were statistically weighted according to sex, age, level of education, and political party affiliation. The random sampling of the person within the household was done using the table of random numbers. Results Health and health care system was the most important issue (58%) during the 2007 parliamentary election and the second most important issue during the 2005 and 2009 elections (46% and 28%). In the 2007 election, health care was viewed as most important by women, respondents with lower education levels, and respondents with lower income. In 2005, the most important health care issues were corruption and lack of funding (45% and 43%, respectively), in 2007 poor organization and lack of funding (43% and 42%, respectively), and in 2009 lack of funding and corruption (51% and 45%, respectively). Conclusion Health and health care system were consistently among the top two issues in all elections from 2005 to 2009. The top three most important health care sector issues were corruption, poor organization, and lack of funding. This indicates that political parties should include solutions to these issues in their health care policymaking. PMID:21990075

  11. Undergraduate Students' Opinions with Regard to Ubiquitous MOOC for Enhancing Cross-Cultural Competence

    Science.gov (United States)

    Plangsorn, Boonrat; Na-Songkhla, Jaitip; Luetkehans, Lara M.

    2016-01-01

    The purpose of this study was to study undergraduate students' opinions with regard to the ubiquitous massive open online course (MOOC) for enhancing cross-cultural competence. This descriptive research applied a survey method. The survey data were collected by using survey questionnaires and online questionnaires from 410 undergraduate students…

  12. Validation of Twitter opinion trends with national polling aggregates: Hillary Clinton vs Donald Trump.

    Science.gov (United States)

    Bovet, Alexandre; Morone, Flaviano; Makse, Hernán A

    2018-06-06

    Measuring and forecasting opinion trends from real-time social media is a long-standing goal of big-data analytics. Despite the large amount of work addressing this question, there has been no clear validation of online social media opinion trend with traditional surveys. Here we develop a method to infer the opinion of Twitter users by using a combination of statistical physics of complex networks and machine learning based on hashtags co-occurrence to build an in-domain training set of the order of a million tweets. We validate our method in the context of 2016 US Presidential Election by comparing the Twitter opinion trend with the New York Times National Polling Average, representing an aggregate of hundreds of independent traditional polls. The Twitter opinion trend follows the aggregated NYT polls with remarkable accuracy. We investigate the dynamics of the social network formed by the interactions among millions of Twitter supporters and infer the support of each user to the presidential candidates. Our analytics unleash the power of Twitter to uncover social trends from elections, brands to political movements, and at a fraction of the cost of traditional surveys.

  13. Opinions and knowledge about climate change science in high school students.

    Science.gov (United States)

    Harker-Schuch, Inez; Bugge-Henriksen, Christian

    2013-10-01

    This study investigates the influence of knowledge on opinions about climate change in the emerging adults' age group (16-17 years). Furthermore, the effects of a lecture in climate change science on knowledge and opinions were assessed. A survey was conducted in Austria and Denmark on 188 students in national and international schools before and after a lecture in climate change science. The results show that knowledge about climate change science significantly affects opinions about climate change. Students with a higher number of correct answers are more likely to have the opinion that humans are causing climate change and that both individuals and governments are responsible for addressing climate change. The lecture in climate change science significantly improved knowledge development but did not affect opinions. Knowledge was improved by 11 % after the lecture. However, the percentage of correct answers was still below 60 % indicating an urgent need for improving climate change science education.

  14. Targeting improved patient outcomes using innovative product listing agreements: a survey of Canadian and international key opinion leaders

    Directory of Open Access Journals (Sweden)

    Thompson M

    2016-08-01

    Full Text Available Melissa Thompson,1 Chris Henshall,2 Louis P Garrison,3 Adrian D Griffin,4 Doug Coyle,2,5 Stephen Long,6 Zayna A Khayat,7 Dana L Anger,1 Rebecca Yu8 1Cornerstone Research Group Inc., Burlington, ON, Canada; 2Health Economics Research Group, Brunel University London, London UK; 3Pharmaceutical Outcomes Research and Policy Program, School of Pharmacy, University of Washington, Seattle, WA, USA; 4Government Affairs & Policy, Johnson & Johnson, High Wycombe, UK; 5School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, ON, Canada; 6Health and Life Sciences, Global Public Affairs, Calgary, AB, 7Health Systems Innovation at MaRS Discovery District, Toronto, ON, Canada; 8Strategic Health Technology Assessment, Government Affairs & Market Access, Janssen Inc., Toronto, ON, Canada Objectives: To address the uncertainty associated with procuring pharmaceutical products, product listing agreements (PLAs are increasingly being used to support responsible funding decisions in Canada and elsewhere. These agreements typically involve financial-based rebating initiatives or, less frequently, outcome-based contracts. A qualitative survey was conducted to improve the understanding of outcome-based and more innovative PLAs (IPLAs based on input from Canadian and international key opinion leaders in the areas of drug manufacturing and reimbursement. Methods: Results from a structured literature review were used to inform survey development. Potential participants were invited via email to partake in the survey, which was conducted over phone or in person. Responses were compiled anonymously for review and reporting. Results: Twenty-one individuals participated in the survey, including health technology ­assessment (HTA key opinion leaders (38%, pharmaceutical industry chief executive officers/vice presidents (29%, ex-payers (19%, and current payers/drug plan managers/HTA (14%. The participants suggested that ~80%–95% of

  15. European car drivers' opinions about road safety measures and in-car devices.

    NARCIS (Netherlands)

    Goldenbeld, C.

    1999-01-01

    In 1991, a representative survey of drivers was conducted in 15 European countries. This project was named `SARTRE' which stands for 'Social Attitudes to Road Traffic Risk in Europe'. The survey focused on drivers' road behaviour, attitudes and opinions concerning drinking and driving, speeding and

  16. The Misperception of Public Opinion Toward Capital Punishment.

    Science.gov (United States)

    McGarrell, Edmund F.; Sandys, Marla

    1996-01-01

    Contends that often lawmakers misread their constituents' opinions on important issues. Presents data from an Indiana survey that suggest support for the death penalty vanishes when citizens are given the option of life in prison without possibility of parole combined with a requirement of work and restitution. (MJP)

  17. Trainee ophthalmologists' opinions on ways to improve cataract ...

    African Journals Online (AJOL)

    Objective: To know the opinions of trainee ophthalmologists on ways to improve cataract surgical rate (CSR) with a view to having insight into actions that should be of high priority for achieving this improvement. Methods: A survey of 27 trainee ophthalmologists using structured self-administered questionnaire. Results: ...

  18. Your opinion counts

    CERN Multimedia

    HR Department

    2008-01-01

    Would you say that your work is stimulating? How do you feel about your working environment and working relationships? Are you proud to be part of this Organization? To find the answers to these questions, the Human Resources Department (HR) will be launching, for the first time, a staff member survey. Via an on-line questionnaire, you will have the opportunity to express your opinions about how you see your work, your expectations and your commitment to the Organization. This will promote dialogue at a turning point in CERN’s history with the start-up of the LHC. An HR steering group is now working on the preparation of this survey. A partnership is being developed with a university, which will play an active role in drawing up the questionnaire and will then carry out a confidential and objective analysis of your replies. Your participation will help the Management, in collaboration with HR, to identify action plans in line with the Organization’s aspirations and t...

  19. A Survey of the Opinions of Mothers, Proprietors and Caregivers on ...

    African Journals Online (AJOL)

    This study investigated the opinions of working mothers, proprietors and caregivers on services provided by day care centres in Ibadan. Sample consists of Two hundred and ninety-five respondents (220 working mothers, 50 Caregivers, and 25 Proprietors). They were randomly selected from the various government ...

  20. Examining Student Opinions on Computer Use Based on the Learning Styles in Mathematics Education

    Science.gov (United States)

    Ozgen, Kemal; Bindak, Recep

    2012-01-01

    The purpose of this study is to identify the opinions of high school students, who have different learning styles, related to computer use in mathematics education. High school students' opinions on computer use in mathematics education were collected with both qualitative and quantitative approaches in the study conducted with a survey model. For…

  1. Transformation of Migration Flows Between the Russian Far East and CIS and non-CIS States

    Directory of Open Access Journals (Sweden)

    Motrich E. L.

    2010-06-01

    Full Text Available Basic trends in the migration processes in the Russian Far East are shown. Special emphasis is placed on the transformation of migration interactions with CIS and non-CIS countries both at the level of the region as a whole, and at the level of the Far Eastern territories of the Russian Federation. An extent of using foreign labor in different periods of the Russian Far East socio-economic development and the regulatory support of this process are shown. Prospects for attracting and utilizing foreign labor are stated

  2. Secondary School Youth Opinion Survey on Energetics within the Programme Nuclear Physics Use - the Past, Present and Future

    International Nuclear Information System (INIS)

    Skulj, B.; Filipin, R.

    2002-01-01

    METHOD OF SURVEY: As a part of the years-long educative programme Nuclear physics use: the past, present and future all parttakers fill in a survey questionaire of 11 topical questions, mostly related to the issues of nuclear energy. The questionaire is filled in before visiting the nuclear power plant Krsko. TARGET GROUP: Technical Musem, in cooperation with Hrvatska elektroprivreda, has been organizing high-school students' visits to the nuclear power plant Krsko since 1989. From all schools that have so far visited the nuclear power plant, Zagreb high schools and technical schools are the most represented ones. The respondents are aged between 16 and 20. The copies of the survey that have been filled in during 2000/2001 are to be analyzed, and the expected number of the respondents is about 600. QUESTIONS: Survey questions reflected several different fields, all in some sort of connection to nuclear energetics. Among them are: -present and future energy resources acceptability of different types of power plants environmental protection and global warming radioactivity radioactive waste issues nuclear power plants types of information resources. Such a wide range of different subjects included in the survey has been chosen so that, after its analysis, further efforts can be taken in quality informing of insufficiently known issues. Also, this kind of public poll will provide the Museum and Hrvatska elektroprivreda with relevant findings about the climate of opinion and the thinking of young generations towards energetics issues and the cause of its future development. The analyzed results of the survey present only a fragment of the material, later to be published in a separate publication. (author)

  3. Stepwise encapsulation and controlled two-stage release system for cis-Diamminediiodoplatinum.

    Science.gov (United States)

    Chen, Yun; Li, Qian; Wu, Qingsheng

    2014-01-01

    cis-Diamminediiodoplatinum (cis-DIDP) is a cisplatin-like anticancer drug with higher anticancer activity, but lower stability and price than cisplatin. In this study, a cis-DIDP carrier system based on micro-sized stearic acid was prepared by an emulsion solvent evaporation method. The maximum drug loading capacity of cis-DIDP-loaded solid lipid nanoparticles was 22.03%, and their encapsulation efficiency was 97.24%. In vitro drug release in phosphate-buffered saline (pH =7.4) at 37.5°C exhibited a unique two-stage process, which could prove beneficial for patients with tumors and malignancies. MTT (3-[4,5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide) assay results showed that cis-DIDP released from cis-DIDP-loaded solid lipid nanoparticles had better inhibition activity than cis-DIDP that had not been loaded.

  4. Developing convolutional neural networks for measuring climate change opinions from social media data

    Science.gov (United States)

    Mao, H.; Bhaduri, B. L.

    2016-12-01

    Understanding public opinions on climate change is important for policy making. Public opinion, however, is typically measured with national surveys, which are often too expensive and thus being updated at a low frequency. Twitter has become a major platform for people to express their opinions on social and political issues. Our work attempts to understand if Twitter data can provide complimentary insights about climate change perceptions. Since the nature of social media is real-time, this data source can especially help us understand how public opinion changes over time in response to climate events and hazards, which though is very difficult to be captured by manual surveys. We use the Twitter Streaming API to collect tweets that contain keywords, "climate change" or "#climatechange". Traditional machine-learning based opinion mining algorithms require a significant amount of labeled data. Data labeling is notoriously time consuming. To address this problem, we use hashtags (a significant feature used to mark topics of tweets) to annotate tweets automatically. For example, hashtags, #climatedenial and #climatescam, are negative opinion labels, while #actonclimate and #climateaction are positive. Following this method, we can obtain a large amount of training data without human labor. This labeled dataset is used to train a deep convolutional neural network that classifies tweets into positive (i.e. believe in climate change) and negative (i.e. do not believe). Based on the positive/negative tweets obtained, we will further analyze risk perceptions and opinions towards policy support. In addition, we analyze twitter user profiles to understand the demographics of proponents and opponents of climate change. Deep learning techniques, especially convolutional deep neural networks, have achieved much success in computer vision. In this work, we propose a convolutional neural network architecture for understanding opinions within text. This method is compared with

  5. The trend of the public opinion upon nuclear power generation in internet blog

    International Nuclear Information System (INIS)

    Maruta, Katsuhiko; Ueda, Yoshitaka

    2011-01-01

    The authors pay attention to and survey internet information which is called 'blog' to grasp how nuclear power generation information is treated in internet and forms public opinion. Examples of the outcomes are as follows. 1) Numbers of blog reference will change by public opinion upon nuclear power generation. A lot of blog references about nuclear power plants are conducted when a big earthquake occurred. 2) As a feature of the report, numbers of the references against nuclear power generation exceed those which are positive for nuclear power. There are a lot of blog reports which are against nuclear power generation and easy to make readers believe that they are true even if they are based on misunderstanding. It is worried that such reports give people too much negative influence for the public opinion upon nuclear power generation. The authors survey short term trend of the internet public opinion after TEPCO's Fukushima Daiichi Power Plants Accident too. As a result, it is made clear that people's concern upon nuclear power became very high and the ratio of the supporters of nuclear power generation changed after the accident. (author)

  6. FLOOD HAZARDS PERCEPTION. THE RESULT OF AN OPINION SURVEY MADE IN THE LITTLE TOWNS FROM LOWER ARIEŞ CORRIDOR

    Directory of Open Access Journals (Sweden)

    IOANA URCAN

    2012-12-01

    Full Text Available Flood hazards perception. The result of an opinion survey made in the little towns from lower Arieş corridor. This paper has been prepared based on information obtained from a survey conducted on a sample of 560 residents from the towns of Turda and Câmpia Turzii, residing in areas with different degrees of exposure to the risk of flooding. The residents were questioned about the floods they had suffered and gave varied responses to the degree of flood damage on the population, to the amount of information and the degree of insurance against floods. The questionnaire was structured on different aspects that emphasized: identification, level of experience, knowledge and information; the perception of the causes that generated and amplified floods; the perception involving authorities in prevention and mitigation of flood damage; availability for implementation of voluntary actions, the degree of insurance and aid to flood. In this study it was taken into account the location of households, the previous flood experience, the age and the education level of the respondents.

  7. Your opinion on climate change might not be as common as you think

    Science.gov (United States)

    Leviston, Z.; Walker, I.; Morwinski, S.

    2013-04-01

    Political and media debate on the existence and causes of climate change has become increasingly factious in several western countries, often resting on claims and counter-claims about what most citizens really think. There are several well-established phenomena in psychology about how people perceive the prevalence of opinions, including the false consensus effect (a tendency to overestimate how common one's `own' opinion is) and pluralistic ignorance (where most people privately reject an opinion, but assume incorrectly that most others accept it). We investigated these biases in people's opinions about the existence and causes of climate change. In two surveys conducted 12 months apart in Australia (n=5,036 n=5,030), respondents were asked their own opinion about the nature of climate change, and then asked to estimate levels of opinion among the general population. We demonstrate that opinions about climate change are subject to strong false consensus effects, that people grossly overestimate the numbers of people who reject the existence of climate change in the broader community, and that people with high false consensus bias are less likely to change their opinions.

  8. Teachers' Opinions of Student Dropout from Formal Music Education Centres of the Canary Islands

    Science.gov (United States)

    Lorenzo Socorro, Sonia; Escandell Bermúdez, María Olga; Castro Sánchez, José Juan

    2016-01-01

    One hundred and eighty-five teachers were surveyed to determine their opinion of student dropout from formal music centres in the Canary Islands. The goal of the study was to investigate the causes of dropout and strategies to prevent it. Teachers' opinions were collected by means of a questionnaire. The influence of the environment on the…

  9. Pre-Service Teachers' Opinions on Teaching Thinking Skills

    Science.gov (United States)

    Akinoglu, Orhan; Karsantik, Yasemin

    2016-01-01

    The purpose of the present study is to determine pre-service teachers' opinions on teaching thinking skills. 134 senior pre-service pre-school, English and mathematics teachers studying at a state university in Istanbul participated in the study which is designed based on survey model. A questionnaire which was developed by the researchers was…

  10. Statistical significance of cis-regulatory modules

    Directory of Open Access Journals (Sweden)

    Smith Andrew D

    2007-01-01

    Full Text Available Abstract Background It is becoming increasingly important for researchers to be able to scan through large genomic regions for transcription factor binding sites or clusters of binding sites forming cis-regulatory modules. Correspondingly, there has been a push to develop algorithms for the rapid detection and assessment of cis-regulatory modules. While various algorithms for this purpose have been introduced, most are not well suited for rapid, genome scale scanning. Results We introduce methods designed for the detection and statistical evaluation of cis-regulatory modules, modeled as either clusters of individual binding sites or as combinations of sites with constrained organization. In order to determine the statistical significance of module sites, we first need a method to determine the statistical significance of single transcription factor binding site matches. We introduce a straightforward method of estimating the statistical significance of single site matches using a database of known promoters to produce data structures that can be used to estimate p-values for binding site matches. We next introduce a technique to calculate the statistical significance of the arrangement of binding sites within a module using a max-gap model. If the module scanned for has defined organizational parameters, the probability of the module is corrected to account for organizational constraints. The statistical significance of single site matches and the architecture of sites within the module can be combined to provide an overall estimation of statistical significance of cis-regulatory module sites. Conclusion The methods introduced in this paper allow for the detection and statistical evaluation of single transcription factor binding sites and cis-regulatory modules. The features described are implemented in the Search Tool for Occurrences of Regulatory Motifs (STORM and MODSTORM software.

  11. Relative Stability of cis- and trans-Hydrindanones

    Directory of Open Access Journals (Sweden)

    Motoo Tori

    2015-01-01

    Full Text Available The relative stabilities of several cis- and trans-hydrindanones were compared using both isomerization experiments and MM2 calculations. The generally believed rule that cis-hydrindanones are more stable than trans-isomers is applicable, but is not always true. This review introduces examples, mainly from studies in our laboratory, to explain these facts.

  12. [Pleural procedures in patients treated by platelet aggregation inhibitors: An opinion survey].

    Science.gov (United States)

    Dangers, L; Similowski, T; Chenivesse, C

    2016-01-01

    When pleural procedures (thoracocentesis, blind pleural biopsies and chest tube insertion) are required in patients taking long-term platelet aggregation inhibitors, the risk of bleeding must be balanced against the risk of arterial thrombosis. Currently, the bleeding risk of pleural procedures is poorly understood. The objective of the survey was to gather the opinion of respiratory physicians regarding the bleeding risk of pleural procedures in patients taking platelet aggregation inhibitors. We emailed a standardized questionnaire designed by the French National Authority for Health to 2697 French respiratory physicians. One hundred and eighty-eight of the 2697 questionnaires were returned (response rate: 7 %). The respiratory physicians declared that they performed an average of 8 pleural procedures per month. One hundred and seventy-five responders (95 %) practised pleural procedures in patients receiving platelet aggregation inhibitors; 68 of them (39 %) reported experiencing haemorrhagic complications. The bleeding risk associated with thoracentesis and chest tube insertion was considered minor by 97.8 and 65 % of responders respectively, whereas it was considered major for blind pleural biopsies by 73.4 %. Respiratory physicians were more reticent about performing pleural procedures in patients treated with clopidogrel than in those taking aspirin. This study provides an overview of how respiratory physicians perceive the bleeding risk associated with pleural procedures in patients taking platelet aggregation inhibitors. Copyright © 2016 SPLF. Published by Elsevier Masson SAS. All rights reserved.

  13. A Global Oral Health Survey of professional opinion using the International Classification of Functioning, Disability and Health.

    Science.gov (United States)

    Dougall, Alison; Molina, Gustavo F; Eschevins, Caroline; Faulks, Denise

    2015-06-01

    The concept of oral health is frequently reduced to the absence of disease, despite existing conceptual models exploring the wider determinants of oral health and quality of life. The International Classification of Functioning, Disability and Health (ICF) (WHO) is designed to qualify functional, social and environmental aspects of health. This survey aimed to reach a consensual description of adult oral health, derived from the ICF using international professional opinion. The Global Oral Health Survey involved a two-round, online survey concerning factors related to oral health including functioning, participation and social environment. Four hundred eighty-six oral health professionals from 74 countries registered online. Professionals were pooled into 18 groups of six WHO world regions and three professional groups. In a randomised stratification process, eight professionals from each pool (n=144) completed the survey. The first round consisted of eight open-ended questions. Open expression replies were analysed for meaningful concepts and linked using established rules to the ICF. In Round 2, items were rated for their relevance to oral health (88% response rate). Eighty-nine ICF items and 30 other factors were considered relevant by at least 80% of participants. International professionals reached consensus on a holistic description of oral health, which could be qualified and quantified using the ICF. These results represent the first step towards developing an ICF Core Set in Oral Health, which would provide a practical tool for reporting outcome measures in clinical practice, for research and epidemiology, and for the improvement of interdisciplinary communication regarding oral health. Professional consensus reached in this survey is the foundation stone for developing an ICF Core Set in Oral Health, allowing the holistic aspects of oral health to be qualified and quantified. This tool is necessary to widen our approach to clinical decision making

  14. The Community Intercomparison Suite (CIS)

    Science.gov (United States)

    Watson-Parris, Duncan; Schutgens, Nick; Cook, Nick; Kipling, Zak; Kershaw, Phil; Gryspeerdt, Ed; Lawrence, Bryan; Stier, Philip

    2017-04-01

    Earth observations (both remote and in-situ) create vast amounts of data providing invaluable constraints for the climate science community. Efficient exploitation of these complex and highly heterogeneous datasets has been limited however by the lack of suitable software tools, particularly for comparison of gridded and ungridded data, thus reducing scientific productivity. CIS (http://cistools.net) is an open-source, command line tool and Python library which allows the straight-forward quantitative analysis, intercomparison and visualisation of remote sensing, in-situ and model data. The CIS can read gridded and ungridded remote sensing, in-situ and model data - and many other data sources 'out-of-the-box', such as ESA Aerosol and Cloud CCI product, MODIS, Cloud CCI, Cloudsat, AERONET. Perhaps most importantly however CIS also employs a modular plugin architecture to allow for the reading of limitless different data types. Users are able to write their own plugins for reading the data sources which they are familiar with, and share them within the community, allowing all to benefit from their expertise. To enable the intercomparison of this data the CIS provides a number of operations including: the aggregation of ungridded and gridded datasets to coarser representations using a number of different built in averaging kernels; the subsetting of data to reduce its extent or dimensionality; the co-location of two distinct datasets onto a single set of co-ordinates; the visualisation of the input or output data through a number of different plots and graphs; the evaluation of arbitrary mathematical expressions against any number of datasets; and a number of other supporting functions such as a statistical comparison of two co-located datasets. These operations can be performed efficiently on local machines or large computing clusters - and is already available on the JASMIN computing facility. A case-study using the GASSP collection of in-situ aerosol observations

  15. Opinions on Energy and Nuclear Power. Research project energy public opinion in Sweden; Aasikter om energi och kaernkraft. Forskningsprojektet Energiopinionen i Sverige

    Energy Technology Data Exchange (ETDEWEB)

    Hedberg, Per; Holmberg, Soeren

    2012-11-01

    This report includes results from a survey concerning the following issues: opinions on the use of nuclear power in Sweden in the long term, to phase out nuclear power or not, risk analysis, which energy sources should Sweden use, trust in stakeholders, as well as ways to decrease energy consumption.

  16. Public Opinion regarding Juvenile Life without Parole in Consecutive Statewide Surveys

    Science.gov (United States)

    Kubiak, Sheryl Pimlott; Allen, Terrence

    2011-01-01

    Abolition of the death penalty results in life without parole (LWOP) as the most severe sanction for convicted juveniles. Although internationally the use of LWOP for juveniles is rare, 2,225 youth have been sentenced to LWOP within the United States. To address the dearth of public opinion on the issue, the authors proposed questions to the…

  17. Optimization of Pseudomonas putida KT2440 as host for the production of cis, cis-muconate from benzoate

    OpenAIRE

    Duuren, van, J.B.J.H.

    2011-01-01

    Optimization of Pseudomonas putida KT2440 as host for the production of cis, cis-muconate from benzoate P. putida KT2440 was used as biocatalyst given its versatile and energetically robust metabolism. Therefore, a mutant was generated and a process developed based on which a life cycle assessment (LCA) was performed. Additionally, the growth related parameters were experimentally obtained to constrain the metabolic model iJP815 further. The mutant Pseudomonas putida KT2440-JD1 was deri...

  18. Opinion leadership and willingness to pay for residential photovoltaic systems

    International Nuclear Information System (INIS)

    Yamamoto, Yoshihiro

    2015-01-01

    According to diffusion theory, opinion leaders play an important role in the diffusion of new technologies through interpersonal communication with potential adopters. This study investigates the role and utility of opinion leadership in photovoltaic (PV) system diffusion. Specifically, the study proposes, examines, and considers the implications of the hypothesis that there is a positive relationship between willingness to pay (WTP) for a PV system and opinion leadership on PV-system adoption. The investigation employed an internet-based questionnaire to assess the use of interpersonal communication in decision-making on adoption, to identify opinion leaders on adoption, and to characterize their WTP. The response pool consisted of 488 individuals who lived in a detached house, owned a residential PV system, and were responsible for making the decision to adopt the system. The results support the hypothesis. Considering that subsidization preferentially incentivizes households with greater WTP to adopt PV systems, this suggests that subsidization is more effective than purchases of PV power under feed-in tariffs in promoting the diffusion of residential PV systems through interpersonal communication. -- Highlights: •Interpersonal communication about the adoption of PV systems is analyzed. •A questionnaire survey is conducted. •Opinion leaders on PV-system adoption are identified. •A relationship is confirmed between willingness to pay and opinion leadership. •Subsidization is more essential than feed-in tariffs from this point of view

  19. Teachers' Opinions about the Use of Body Language

    Science.gov (United States)

    Benzer, Ahmet

    2012-01-01

    Effective communication occurs with non-verbal and verbal tools. In this study the body language as non-verbal communication tool is taken to be examined, and teachers' opinions about the use and importance of body language in education are surveyed. Eight open-ended questions are asked to 100 teachers. As a result, it is shown that teachers…

  20. Limitations on the compensation of gamete donors: a public opinion survey.

    Science.gov (United States)

    Lee, Malinda S; Farland, Leslie V; Missmer, Stacey A; Ginsburg, Elizabeth S

    2017-06-01

    To determine public opinion on gamete donor compensation. Cross-sectional web-based survey. Not applicable. A nationally representative sample of 1,427 people in the United States. Not applicable. Support for the compensation of gamete donors. Of 1,427 respondents, 51 (4%) disagreed with use of IVF for any indication, and 232 (16%) believed that oocyte and/or sperm donation to be always unacceptable. Of the remaining 1,185 respondents, 953 (80%) supported and 41 (4%) opposed paying sperm donors; 1,063 (90%) supported and 24 (2%) opposed paying oocyte donors. Of respondents, 90% believed that appropriate compensation for one cycle of oocyte donation should be less than $10,000. A total of 559 (47%) supported a limit on sperm donor compensation and 544 (46%) supported a limit on oocyte donor compensation. Individuals who had personal knowledge of someone with infertility or who used assisted reproductive technology (ART), and Republicans compared with Democrats, were more likely to support limits on both oocyte and sperm donor compensation. Divorced compared with married respondents were less likely to support limits on gamete donor compensation. Men were less likely to support limits on sperm donor compensation. Most respondents in a nationally representative cohort support compensating gamete donors. Although most do not support limits on gamete donor compensation, most agree the appropriate payment for one cycle of oocyte donation is in line with former American Society for Reproductive Medicine guidelines. Copyright © 2017 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

  1. Examining Characteristics of Opinion Leaders in Social Media: A Motivational Approach

    Directory of Open Access Journals (Sweden)

    Stephan Winter

    2016-08-01

    Full Text Available Social networking sites offer various opportunities to express opinions on politics and public affairs and to disseminate information to a large circle of acquaintances. The present research aims to identify the characteristics of people who consider themselves as opinion leaders on these new channels, the features they use in order to influence others, and the psychological motives they pursue. A survey ( N  = 527 among Facebook users identified political interest and personality strength as significant predictors of perceived Facebook opinion leadership, while the influence of extraversion was not significant. Those who write private messages on political debates do this in order to raise awareness of specific topics, while opinion expression in public status updates is also strongly connected to self-presentational goals (impression motivation. Moreover, the motives of presenting oneself positively and convincing others are particularly important for people with high personality strength. The present findings extend previous knowledge by redefining the concept of opinion leadership in new media environments and describing motivational links between individuals’ predispositions and their activities to influence others’ opinions. On a practical level, the pronounced role of self-presentational motives is likely to have important implications for the dynamics of public debates in social media.

  2. Chiral synthesis of (Z)-3-cis-6,7-cis-9,10-diepoxyhenicosenes, sex pheromone components of the satin moth, Leucoma salicis.

    Science.gov (United States)

    Wimalaratne, Priyantha D C; Slessor, Keith N

    2004-06-01

    All four isomers of (Z)-3-cis-6,7-cis-9,10-diepoxyhenicosenes, 1-4, have been synthesized using D-xylose as the chirally pure starting material. D-Xylose was first converted to 2-deoxy-4,5-O-isopropylidene-3-t-butyldimethylsilyl-D-threopentose 11, via several steps of selective protection, dehydroxylation, and deprotection. Wittig coupling of 11 with nonyltriphenylphosphonium bromide followed by hydrogenation and acid catalyzed deprotection of hydroxyl groups yielded the chiral (2R,3R)-1,2,3-triol, 14, which was used as the precursor for the C-8 to C-21 unit of the (Z)-3-cis-6,7-cis-9,10-diepoxyhenicosenes. Selective tosylation of 14 followed by stereospecific cyclization yielded (2R,3R)-1,2-epoxytetradecan-3-ol, 16, which was then divergently converted to the t-butyldimethylsilyl ether 17 and tosylate 22, respectively. Establishment of the C-5 through C-7 unit of the target molecules was accomplished via regiospecific coupling of 17 with 1-t-butyldimethylsiloxy-2-propyne to form 18. Stepwise transformation of 18 via the formation of tosylate 19, desilylation, and stereospecific cyclization to form epoxy alcohol 20, followed by P2-Ni reduction yielded a key intermediate, allylic epoxy alcohol (Z)-2-(5S,6R)-cis-5,6-epoxyheptadecen-1-ol, 21. Similarly, the coupling of 22 with 1-t-butyldimethylsiloxy-2-propyne yielded 23, which was stereospecifically cyclized to form 24. Desilylation and P2-Ni reduction of 24 gave the antipodal intermediate, (Z)-2-(5R,6S)-cis-5,6-epoxyheptadecen-1-ol, 26. Asymmetric epoxidation of antipodes 21 and 26 with (L)- or (D)-diethyl tartrates resulted in the formation of diepoxy alcohols 27 and 29 from 21, and 33 and 31 from 26, respectively. Tosylation of these diepoxy alcohols followed by coupling with lithium dibutenyl cuprate yielded the four stereoisomers of (Z)-3-cis-6,7-cis-9,10-diepoxyhenicosenes, 1-4. Analysis of the retention characteristics of these materials revealed that one or both of the S*,R*,S*,R* stereoisomers comprise the

  3. The public opinion and ATC

    International Nuclear Information System (INIS)

    Ballera, J.

    2010-01-01

    The role of the media is essential to adopt a final decision in relation to the location of a Centralized Temporary Storage (ATC)in Spain. to the deliberative process is public, open and transparent, as included in Royal Decree that created the Inter ministerial Commission responsible for overseeing the procedure, it is necessary for that citizens has information, clear and unequivocal. indicators such as the special edition of the Eurobarometer survey published in June 2008 showed that it is moving towards a truly informed public opinion in these matters. (Author)

  4. Multiple Functional Variants in cis Modulate PDYN Expression.

    Science.gov (United States)

    Babbitt, Courtney C; Silverman, Jesse S; Haygood, Ralph; Reininga, Jennifer M; Rockman, Matthew V; Wray, Gregory A

    2010-02-01

    Understanding genetic variation and its functional consequences within cis-regulatory regions remains an important challenge in human genetics and evolution. Here, we present a fine-scale functional analysis of segregating variation within the cis-regulatory region of prodynorphin, a gene that encodes an endogenous opioid precursor with roles in cognition and disease. In order to characterize the functional consequences of segregating variation in cis in a region under balancing selection in different human populations, we examined associations between specific polymorphisms and gene expression in vivo and in vitro. We identified five polymorphisms within the 5' flanking region that affect transcript abundance: a 68-bp repeat recognized in prior studies, as well as two microsatellites and two single nucleotide polymorphisms not previously implicated as functional variants. The impact of these variants on transcription differs by brain region, sex, and cell type, implying interactions between cis genotype and the differentiated state of cells. The effects of individual variants on expression level are not additive in some combinations, implying epistatic interactions between nearby variants. These data reveal an unexpectedly complex relationship between segregating genetic variation and its expression-trait consequences and highlights the importance of close functional scrutiny of natural genetic variation within even relatively well-studied cis-regulatory regions.

  5. Interest group opinions about fuel reduction in southern Appalachia

    Science.gov (United States)

    Carin E. Vadala; Robert D. Bixler; Thomas A. Waldrop

    2013-01-01

    Opinions of interested publics and interest groups (n = 640) about fuel reduction (FR) in the Southern Appalachian Mountains were investigated through social survey using both pictorial and written questions. The study identified three discrete groups based on knowledge of forest history in the Southern Appalachian Mountains, attitudes toward social and ecological...

  6. Leader's opinion priority bounded confidence model for network opinion evolution

    Science.gov (United States)

    Zhu, Meixia; Xie, Guangqiang

    2017-08-01

    Aiming at the weight of trust someone given to participate in the interaction in Hegselmann-Krause's type consensus model is the same and virtual social networks among individuals with different level of education, personal influence, etc. For differences between agents, a novelty bounded confidence model was proposed with leader's opinion considered priority. Interaction neighbors can be divided into two kinds. The first kind is made up of "opinion leaders" group, another kind is made up of ordinary people. For different groups to give different weights of trust. We also analyzed the related characteristics of the new model under the symmetrical bounded confidence parameters and combined with the classical HK model were analyzed. Simulation experiment results show that no matter the network size and initial view is subject to uniform distribution or discrete distribution. We can control the "opinion-leader" good change the number of views and values, and even improve the convergence speed. Experiment also found that the choice of "opinion leaders" is not the more the better, the model well explain how the "opinion leader" in the process of the evolution of the public opinion play the role of the leader.

  7. Characteristics associated with requests by pathologists for second opinions on breast biopsies.

    Science.gov (United States)

    Geller, Berta M; Nelson, Heidi D; Weaver, Donald L; Frederick, Paul D; Allison, Kimberly H; Onega, Tracy; Carney, Patricia A; Tosteson, Anna N A; Elmore, Joann G

    2017-11-01

    Second opinions in pathology improve patient safety by reducing diagnostic errors, leading to more appropriate clinical treatment decisions. Little objective data are available regarding the factors triggering a request for second opinion despite second opinion consultations being part of the diagnostic system of pathology. Therefore we sought to assess breast biopsy cases and interpreting pathologists characteristics associated with second opinion requests. Collected pathologist surveys and their interpretations of 60 test set cases were used to explore the relationships between case characteristics, pathologist characteristics and case perceptions, and requests for second opinions. Data were evaluated by logistic regression and generalised estimating equations. 115 pathologists provided 6900 assessments; pathologists requested second opinions on 70% (4827/6900) of their assessments 36% (1731/4827) of these would not have been required by policy. All associations between case characteristics and requesting second opinions were statistically significant, including diagnostic category, breast density, biopsy type, and number of diagnoses noted per case. Exclusive of institutional policies, pathologists wanted second opinions most frequently for atypia (66%) and least frequently for invasive cancer (20%). Second opinion rates were higher when the pathologist had lower assessment confidence, in cases with higher perceived difficulty, and cases with borderline diagnoses. Pathologists request second opinions for challenging cases, particularly those with atypia, high breast density, core needle biopsies, or many co-existing diagnoses. Further studies should evaluate whether the case characteristics identified in this study could be used as clinical criteria to prompt system-level strategies for mandating second opinions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  8. CisSERS: Customizable In Silico Sequence Evaluation for Restriction Sites.

    Science.gov (United States)

    Sharpe, Richard M; Koepke, Tyson; Harper, Artemus; Grimes, John; Galli, Marco; Satoh-Cruz, Mio; Kalyanaraman, Ananth; Evans, Katherine; Kramer, David; Dhingra, Amit

    2016-01-01

    High-throughput sequencing continues to produce an immense volume of information that is processed and assembled into mature sequence data. Data analysis tools are urgently needed that leverage the embedded DNA sequence polymorphisms and consequent changes to restriction sites or sequence motifs in a high-throughput manner to enable biological experimentation. CisSERS was developed as a standalone open source tool to analyze sequence datasets and provide biologists with individual or comparative genome organization information in terms of presence and frequency of patterns or motifs such as restriction enzymes. Predicted agarose gel visualization of the custom analyses results was also integrated to enhance the usefulness of the software. CisSERS offers several novel functionalities, such as handling of large and multiple datasets in parallel, multiple restriction enzyme site detection and custom motif detection features, which are seamlessly integrated with real time agarose gel visualization. Using a simple fasta-formatted file as input, CisSERS utilizes the REBASE enzyme database. Results from CisSERS enable the user to make decisions for designing genotyping by sequencing experiments, reduced representation sequencing, 3'UTR sequencing, and cleaved amplified polymorphic sequence (CAPS) molecular markers for large sample sets. CisSERS is a java based graphical user interface built around a perl backbone. Several of the applications of CisSERS including CAPS molecular marker development were successfully validated using wet-lab experimentation. Here, we present the tool CisSERS and results from in-silico and corresponding wet-lab analyses demonstrating that CisSERS is a technology platform solution that facilitates efficient data utilization in genomics and genetics studies.

  9. Monoclonal antibodies to DNA modified with cis- or trans-diamminedichloroplatinum(II)

    International Nuclear Information System (INIS)

    Sundquist, W.I.; Lippard, S.J.; Stollar, B.D.

    1987-01-01

    Murine monoclonal antibodies that bind selectively to adducts formed on DNA by the antitumor drug cis-diamminedichloroplatinum(II), cis-DDP, or to the chemothrapeutically inactive trans isomer trans-DDP were elicited by immunization with calf thymus DNA modified with either cis- or trans-DDP at ratios of bound platinum per nucleotide, (D/N)/sub b/, of 0.06-0.08. The binding of two monoclonal antibodies to cis-DDP-modified DNA was competitively inhibited in an enzyme-linked immunosorbent assay (ELISA) by 4-6 nM concentrations of cis-DDP bound to DNA. Adducts formed by cis-DDP on other synthetic DNA polymers did not inhibit antibody binding to cis-DDP-DNA. The biologically active compounds [Pt(en)Cl 2 ], [Pt(dach)Cl 2 ], and [Pt(NH 3 ) 2 (cbdca)] (carboplatin) all formed antibody-detectable adducts on DNA, whereas the inactive platinum complexes trans-DDP and [Pt(dien)Cl]Cl (dien, diethylenetriamine) did not. The monoclonal antibodies therefore recognize a bifunctional Pt-DNA adduct with cis stereochemistry in which platinum is coordinated by two adjacent guanines or, to a lesser degree, by adjacent adenine and guanine. A monoclonal antibody raised against trans-DDP-DNA was competitively inhibited in an ELISA by 40 nM trans-DDP bound to DNA. This antibody crossreacted with unmodified, denatured DNA. The recognition of cis- or trans-DDP-modified DNAs by monoclonal antibodies thus parallels the known modes of DNA binding of these compounds and may correlate with their biological activities

  10. Stepwise encapsulation and controlled two-stage release system for cis-Diamminediiodoplatinum

    Directory of Open Access Journals (Sweden)

    Chen Y

    2014-06-01

    Full Text Available Yun Chen,1,* Qian Li,1,2,* Qingsheng Wu1 1Department of Chemistry, Key Laboratory of Yangtze River Water Environment, Ministry of Education, Tongji University, Shanghai; 2Shanghai Institute of Quality Inspection and Technical Research, Shanghai, People’s Republic of China *These authors contributed equally to this work Abstract: cis-Diamminediiodoplatinum (cis-DIDP is a cisplatin-like anticancer drug with higher anticancer activity, but lower stability and price than cisplatin. In this study, a cis-DIDP carrier system based on micro-sized stearic acid was prepared by an emulsion solvent evaporation method. The maximum drug loading capacity of cis-DIDP-loaded solid lipid nanoparticles was 22.03%, and their encapsulation efficiency was 97.24%. In vitro drug release in phosphate-buffered saline (pH =7.4 at 37.5°C exhibited a unique two-stage process, which could prove beneficial for patients with tumors and malignancies. MTT (3-[4,5-dimethylthiazol-2-yl]-2, 5-diphenyltetrazolium bromide assay results showed that cis-DIDP released from cis-DIDP-loaded solid lipid nanoparticles had better inhibition activity than cis-DIDP that had not been loaded. Keywords: stearic acid, emulsion solvent evaporation method, drug delivery, cis-DIDP, in vitro

  11. Connections between Transcription Downstream of Genes and cis-SAGe Chimeric RNA.

    Science.gov (United States)

    Chwalenia, Katarzyna; Qin, Fujun; Singh, Sandeep; Tangtrongstittikul, Panjapon; Li, Hui

    2017-11-22

    cis-Splicing between adjacent genes (cis-SAGe) is being recognized as one way to produce chimeric fusion RNAs. However, its detail mechanism is not clear. Recent study revealed induction of transcriptions downstream of genes (DoGs) under osmotic stress. Here, we investigated the influence of osmotic stress on cis-SAGe chimeric RNAs and their connection to DoGs. We found,the absence of induction of at least some cis-SAGe fusions and/or their corresponding DoGs at early time point(s). In fact, these DoGs and their cis-SAGe fusions are inversely correlated. This negative correlation was changed to positive at a later time point. These results suggest a direct competition between the two categories of transcripts when total pool of readthrough transcripts is limited at an early time point. At a later time point, DoGs and corresponding cis-SAGe fusions are both induced, indicating that total readthrough transcripts become more abundant. Finally, we observed overall enhancement of cis-SAGe chimeric RNAs in KCl-treated samples by RNA-Seq analysis.

  12. An exploration of the dynamics and influences upon second medical opinion consultations in cancer care.

    Science.gov (United States)

    Philip, Jennifer; Gold, Michelle; Schwarz, Max; Komesaroff, Paul

    2011-03-01

    The aim of this study was to explore the dynamics within second medical opinion consultations in patients with cancer. Semi-structured interviews were held with four oncologists and were subjected to a thematic analysis to define the broad issues. These formed the basis of a survey distributed to Australian medical oncologists. Overall 65 surveys were returned representing an overall response rate of 30% (10% and 63% electronic and hardcopy response rates, respectively). The dynamics in giving second medical opinions are influenced by the collegiate relationships of the doctors. Nearly two-thirds of oncologists believed that the first doctors' treatment and recommendations influenced the outcome of the second opinion, more than one-third believed the outcome was influenced by the relationship between the two doctors, and 41% believed the public nature of a second opinion was influential. In each case, these figures were more than double their assessments of patients' beliefs of these influences. Care was taken not to criticise the primary doctor. Second medical opinions provide an opportunity for oncologists to review medical care and engage in enhanced communication with patients who have additional needs. These consultations do not, however, occur in a vacuum but are influenced by the need to attend to relationships between the patient and their primary doctor and between the doctors themselves. The second medical opinion is embedded within a network of relationships and within the illness journey. © 2010 Blackwell Publishing Asia Pty Ltd.

  13. Enantioselective disruption of the endocrine system by Cis-Bifenthrin in the male mice.

    Science.gov (United States)

    Jin, Yuanxiang; Wang, Jiangcong; Pan, Xiuhong; Miao, Wenyu; Lin, Xiaojian; Wang, Linggang; Fu, Zhengwei

    2015-07-01

    Bifenthrin (BF), as a chiral pyrethroid, is widely used to control field and household pests in China. At present, the commercial BF is a mixed compound containing cis isomers (cis-BF) including two enantiomers of 1R-cis-BF and 1S-cis-BF. In the present study, the two individual cis-BF enantiomers were separated by a preparative supercritical fluid chromatography. Then, four week-old adolescent male ICR mice were orally administered 1R-cis-BF and 1S-cis-BF separately daily for 3 weeks at doses of 0, 7.5 and 15 mg/kg/day, respectively. Results showed that the transcription status of some genes involved in cholesterol synthesis and transport as well as testosterone (T) synthesis in the testes were influenced by cis-BF enantiomers. Especially, we observed that the transcription status of key genes on the pathway of T synthesis including cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc) and cytochrome P450 17α-hydroxysteroid dehydrogenase (P45017α)) were selectively altered in the testis of mice when treated with 1S-cis-BF, suggesting that it is the possible reason to explain why the lower serum T concentration in 1S-cis-BF treated group. Taken together, it concluded that both of the cis-BF enantiomers have the endocrine disruption activities, while 1S-cis-BF was higher than 1R-cis-BF in mice when exposed during the puberty. The data was helpful to understand the toxicity of cis-BF in mammals under enantiomeric level. © 2014 Wiley Periodicals, Inc.

  14. Students’ opinions about modern lecture: development path

    Directory of Open Access Journals (Sweden)

    Tatyana A. Astashova

    2017-01-01

    Full Text Available As an objective of the research, the author set the task of identifying students’ opinion and opinion of lecturers about the purpose of the lectures at the university, about the role of the lecturer and preferred form of lectures. As a result of the research, it was necessary to answer the following important questions: What are the objectives of the lecture and the role of the lecturer? Which lectures are more preferable: traditional or interactive? What do lecturers expect from the lecture, do they consider it an advantage or an unnecessary educational activity?The materials were developed for the survey (questionnaire to conduct the research and analyze the results obtained. The students were surveyed before training and after completion of the semester. The study involved 200 students of all areas of Mechanics and Technology Faculty of Novosibirsk State Technical University. Statistical analysis was used for the analysis of the results.As a result, the experiment revealed nonconformity of opinions of students about the purpose of the lecture and the role of a lecturer before the training and after the end of the semester. Lectures, according to students, should help to implement all kinds of practical and independent assignments.Educational standards imply a reduction in the hours of classroom training and an increase in independent work, and the majority of students are not ready (do not want to to study the materials on the topics of discipline completely independently or partially.It revealed a contradiction in opinion, what form of organization of the lecture classes is more interesting to students, which can increase the motivation of the visit and work on the lectures.The technology of designing the educational process in the conditions of the mixed training is proposed, applying the technological map.The technological map is presented in the form of stages of designing the educational process, including recommendations on the use of

  15. Comparison between the public opinion and the image of public opinion on nuclear power generation. From the viewpoint of risk communication

    International Nuclear Information System (INIS)

    Matsuda, Toshihiro

    2003-01-01

    One objective for risk communication is to improve the understanding of public values and concerns. This paper examined the perceptions of nuclear power plant engineers of an electric power company, about public values and concerns regarding nuclear power generation (image of public opinion), and compared them with actual public opinion. The image of public opinion was surveyed by questionnaire method. In the questionnaire, the subjects were asked to estimate the most preferred answer given to questions posed to the Japanese public. For some questions, subjects were asked to estimate the percentage of Japanese who selected a certain answer for a question or the distribution of the answers. The results showed: (1) Nuclear power plant engineers correctly recognized the existence of high anxiety in the public's mind concerning nuclear power generation. (2) Engineers were apt to underestimate the percentage of Japanese who think nuclear power generation is useful in our society. (3) The majority of Japanese assume that when nuclear power plant accidents occur radioactive leakage is so severe that it affects the health of inhabitants. However, the engineers were apt to estimate that the majority of Japanese think radioactive leakage is not so severe. (4) Engineers correctly recognized that the majority of Japanese think it is a realistic option to use the nuclear power generation. However, they incorrectly estimated that only 40% of Japanese think it is a realistic option to use the nuclear power generation when in fact 67% think so. These gaps between public opinion and the image of public opinion by the engineers were classified into two groups, one that stems from the cognitive bias when people estimate public opinion and one that is inherent in the engineers of nuclear power plants. (author)

  16. Changing opinions about research by Saudi medical students

    Directory of Open Access Journals (Sweden)

    Abulaban A

    2017-08-01

    Full Text Available Ahmad Abulaban, Abdulrahman Alharbi, Osama BinDajam, Mohammed Al Jarbou, Hatem Alharbi, Faiz Alanazi, Khalid Aldamiri, Ahmed Althobaiti, Abdulla Al Sayyari Department of Medicine, Division of Neurology, King Saud bin-Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia Objective: The objective of this study was to investigate and compare the opinions and attitudes of medical students toward medical research in five Saudi universities and examine the changes observed in these opinions and attitudes in one of these universities over a period of time.Methods: This is a cross-sectional study conducted among medical students in five Saudi universities. This study was based on a survey undertaken in 2015. The survey consisted of five questions inquiring about the opinions and attitudes of medical students toward medical research. The same survey was carried out 8 years earlier in one of these universities (King Abdulaziz University [KAU], and the results obtained during the two periods (2007 and 2015 were compared.Results: A convenient sample of 924 students was selected from five Saudi universities. Ninety-five (10.3% of the medical students were not aware of the usefulness and importance scientific research will have on their future careers. A total of 409 (44.3% stated that they had no knowledge on how to conduct scientific research. On the other hand, a vast majority of medical students (98.1% expressed a willingness and interest to participate in scientific research if provided with an opportunity. The percentage of students from KAU strongly agreeing to participate in research rose from 33.1% in 2007 to 81.5% in 2015 (P=0.001. Of all the students surveyed, 431 (46.6% had participated in scientific research as undergraduates.Conclusion: Most students in five Saudi universities expressed enthusiasm for participating in a research project, but only a few of them had

  17. [Opinions and attitudes regarding sexuality: Brazilian national research, 2005].

    Science.gov (United States)

    Paiva, Vera; Aranha, Francisco; Bastos, Francisco I

    2008-06-01

    To describe opinions and attitudes concerning sexuality of the Brazilian urban population. A population survey was carried out in 2005 on a representative sample of 5,040 interviewees. An analysis of the attitudes regarding sexual initiation and sexual education of teenagers, considering gender, age, schooling, income, marital status, color, geographic region and opinion on fidelity, homosexuality, and masturbation. The results were contrasted with a similar survey carried out in 1998, when possible. Most interviewees selected the "sex is evidence of love" option when describing the meaning of sex. As in 1998, the majority was in favor of sexual initiation after marriage (63.9% for women vs. 52.4% for men initiation); results differed among religions. School teenage education on the use of condoms was supported by 97% of the interviewees across all social groups. The proportion of Brazilians who agreed with having access to condoms in health services (95%) and at school (83.6%) was high. Fidelity remained an almost unanimous value and there was an increase, in 2005, in the proportion of those in favor of sexual initiation after marriage, and in the rate of acceptance of masturbation and homosexuality compared to the 1998 survey. The younger generations tend to be more tolerant and egalitarian. As observed in other countries, this study confirms the difficulty in establishing a single dimension that guides sexual life ("liberal" vs "conservative"). The study suggests that the normativity concerning sexual activity should be understood in the light of the local culture and social organization of sexuality, considered by the STD/Aids programs. Opinions in favor of free access to preservatives at school clash with the slower results obtained in fighting the stigma and discriminating against homosexual minorities. The design of laical policies on sexuality allow for the dialog across different perspectives.

  18. Implementing Global Fund programs: a survey of opinions and experiences of the Principal Recipients across 69 countries.

    Science.gov (United States)

    Wafula, Francis; Marwa, Charles; McCoy, David

    2014-03-24

    Principal Recipients (PRs) receive money from the Global Fund to fight AIDS, Tuberculosis and Malaria (Global Fund) to manage and implement programs. However, little research has gone into understanding their opinions and experiences. This survey set out to describe these, thereby providing a baseline against which changes in PR opinions and experiences can be assessed as the recently introduced new funding model is rolled out. An internet based questionnaire was administered to 315 PRs. A total of 115 responded from 69 countries in Africa, Asia, Eastern Europe and Latin America. The study was conducted between September and December 2012. Three quarters of PRs thought the progress update and disbursement request (PU/DR) system was a useful method of reporting grant progress. However, most felt that the grant negotiation processes were complicated, and that the grant rating system did not reflect performance.While nearly all PRs were happy with the work being done by sub-Recipients (92%) and Fund Portfolio Managers (86%), fewer were happy with the Office of the Inspector General (OIG). Non-government PRs were generally less happy with the OIG's work compared to government PRs.Most PRs thought the Global Fund's Voluntary Pooled Procurement system made procurement easier. However, only 29% said the system should be made compulsory.When asked which aspects of the Global Fund's operations needed improvement, most PRs said that the Fund should re-define and clarify the roles of different actors, minimize staff turnover at its Secretariat, and shorten the grant application and approval processes. All these are currently being addressed, either directly or indirectly, under a new funding model. Vigorous assessments should nonetheless follow the roll-out of the new model to ensure the areas that are most likely to affect PR performance realize sustained improvement. Opinions and experiences with the Global Fund were varied, with PRs having good communication with Fund

  19. CisSERS: Customizable In Silico Sequence Evaluation for Restriction Sites.

    Directory of Open Access Journals (Sweden)

    Richard M Sharpe

    Full Text Available High-throughput sequencing continues to produce an immense volume of information that is processed and assembled into mature sequence data. Data analysis tools are urgently needed that leverage the embedded DNA sequence polymorphisms and consequent changes to restriction sites or sequence motifs in a high-throughput manner to enable biological experimentation. CisSERS was developed as a standalone open source tool to analyze sequence datasets and provide biologists with individual or comparative genome organization information in terms of presence and frequency of patterns or motifs such as restriction enzymes. Predicted agarose gel visualization of the custom analyses results was also integrated to enhance the usefulness of the software. CisSERS offers several novel functionalities, such as handling of large and multiple datasets in parallel, multiple restriction enzyme site detection and custom motif detection features, which are seamlessly integrated with real time agarose gel visualization. Using a simple fasta-formatted file as input, CisSERS utilizes the REBASE enzyme database. Results from CisSERS enable the user to make decisions for designing genotyping by sequencing experiments, reduced representation sequencing, 3'UTR sequencing, and cleaved amplified polymorphic sequence (CAPS molecular markers for large sample sets. CisSERS is a java based graphical user interface built around a perl backbone. Several of the applications of CisSERS including CAPS molecular marker development were successfully validated using wet-lab experimentation. Here, we present the tool CisSERS and results from in-silico and corresponding wet-lab analyses demonstrating that CisSERS is a technology platform solution that facilitates efficient data utilization in genomics and genetics studies.

  20. Using Spatial, Economic, and Ecological Opinion Data to Inform Gray Wolf Conservation.

    Science.gov (United States)

    Berry, Meredith S; Nickerson, Norma P; Metcalf, Elizabeth Covelli

    2016-09-01

    Public opinion can be an influential factor in wildlife management decisions. Evaluating public opinions can help legitimize, or delegitimize, management and facilitate long-term conservation goals. This is especially true for the controversial issues surrounding the management of predators. We surveyed Montana, USA, residents during summer of 2013 to measure public opinion regarding economic and ecological impacts of the gray wolf ( Canis lupus ), and current management of this species. Although opinions were polarized in some areas, a greater percentage of Montanans think that wolves negatively affect the economy, but impact tourism (which contributes to the economy) positively. These differences may reflect the belief that rancher economic losses from wolf predation of cattle is greater than overall tourism gains related to wolves (e.g., wolf-watching), in addition to the perception of wolves negatively affecting big game (e.g., elk [ Cervus canadensis ]). Results also show that a slightly greater percentage of Montanans feel that wolves positively rather than negatively affect the ecosystem. Regarding specific practices, more Montanans than not have a positive opinion of maintaining wolves on the landscape and also support hunting of wolves. More Montanans hold negative rather than positive opinions, however, regarding wolf trapping. This result was most evident in western Montana as assessed by a spatial distribution of opinions by county and has implications for current wolf management and nontarget species. Results of ordinal regression analyses revealed that big game hunters, males, and those who held negative opinions of the effect of wolves on the Montana ecosystem and economy were significantly more likely to support both hunting and trapping practices. Living in western Montana predicted positive opinions of hunting, but alternatively, negative opinions of trapping. These results provide an understanding of public opinion of wolf management by county as

  1. Using Spatial, Economic, and Ecological Opinion Data to Inform Gray Wolf Conservation

    Science.gov (United States)

    Berry, Meredith S.; Nickerson, Norma P.; Metcalf, Elizabeth Covelli

    2018-01-01

    Public opinion can be an influential factor in wildlife management decisions. Evaluating public opinions can help legitimize, or delegitimize, management and facilitate long-term conservation goals. This is especially true for the controversial issues surrounding the management of predators. We surveyed Montana, USA, residents during summer of 2013 to measure public opinion regarding economic and ecological impacts of the gray wolf (Canis lupus), and current management of this species. Although opinions were polarized in some areas, a greater percentage of Montanans think that wolves negatively affect the economy, but impact tourism (which contributes to the economy) positively. These differences may reflect the belief that rancher economic losses from wolf predation of cattle is greater than overall tourism gains related to wolves (e.g., wolf-watching), in addition to the perception of wolves negatively affecting big game (e.g., elk [Cervus canadensis]). Results also show that a slightly greater percentage of Montanans feel that wolves positively rather than negatively affect the ecosystem. Regarding specific practices, more Montanans than not have a positive opinion of maintaining wolves on the landscape and also support hunting of wolves. More Montanans hold negative rather than positive opinions, however, regarding wolf trapping. This result was most evident in western Montana as assessed by a spatial distribution of opinions by county and has implications for current wolf management and nontarget species. Results of ordinal regression analyses revealed that big game hunters, males, and those who held negative opinions of the effect of wolves on the Montana ecosystem and economy were significantly more likely to support both hunting and trapping practices. Living in western Montana predicted positive opinions of hunting, but alternatively, negative opinions of trapping. These results provide an understanding of public opinion of wolf management by county as

  2. Kyoto or non-Kyoto - people or politics: results of recent public opinion surveys on energy and climate change

    International Nuclear Information System (INIS)

    Ashworth, Peta; Gardner, John; Littleboy, Anna

    2007-01-01

    Full text: We present the results of a survey of an Australian public opinion survey in the area of climate change and energy technologies and compare the results with similar studies conducted in the other major non-Kyoto-adherent party, the United States, as well as to Kyoto-adherent countries including the UK, Japan, Sweden and Spain. We explore some of the differences and similarities in attitudes and understandings. In our survey, Australians place environment, health care and petrol prices as the most important issues facing their country, while in America it is terrorism, health care and the economy and in the UK it is asylum seekers, crime and health care. In many other areas, the differences are considerably smaller and there are some remarkable similarities. Whereas climate change is increasingly cited as the leading environmental issue in most countries surveyed, in Australia, climate change is second to water availability as the top environmental concern. The study examines where climate change and energy technologies fit within these broader national and environmental priorities and identifies the general public's preferred solutions. We find clear support in Australia and the other countries surveyed for renewable energy technologies, particularly solar energy and to a lesser extent wind and biomass energy. We also find considerable disagreement in all countries regarding the future of nuclear power as well as with regard to carbon dioxide capture and storage technologies (albeit the latter with much larger uncertainty). The paper also explores the current knowledge levels of the general public in a number of countries about carbon dioxide emissions and how much as individuals, they are prepared to pay to mitigate greenhouse gas emissions. We find that, in general, at a more detailed level in terms of both attitudes and understandings of energy and climate issues there is considerable agreement across disparate countries Gudged on their national

  3. The efficacy of 9-cis retinoic acid in experimental models of cancer.

    Science.gov (United States)

    Gottardis, M M; Lamph, W W; Shalinsky, D R; Wellstein, A; Heyman, R A

    1996-01-01

    9-cis retinoic acid (9-cis RA) is a retinoid receptor pan-agonist that binds with high affinity to both retinoic acid receptors (RARs) and retinoid X receptors (RXRs). Using a variety of in vivo and in vitro cancer models, we present experimental data that 9-cis RA has activity as a potential chemotherapeutic agent. Treatment of the human promyelocytic leukemia cell line HL-60 with 9-cis RA decreases cell proliferation, increases cell differentiation, and increases apoptosis. Induction of apoptosis correlates with an increase in tissue transglutaminase (type II) activity. In vivo, 9-cis RA induces complete tumor regression of an early passage human lip squamous cell carcinoma xenograft. Finally, 9-cis RA inhibits the anchorage-independent growth of the human breast cancer cell lines MCF-7 and LY2 (an antiestrogen-resistant MCF-7 variant). Transient co-transfection assays indicate that 9-cis RA inhibits estrogen receptor transcription of an ERE-tk-LUC reporter through RAR or RXR receptors. These data suggest that retinoid receptors can antagonize estrogen-dependent transcription and provides one possible mechanism for the inhibition of cell growth by 9-cis RA in breast cancer cell lines. In summary, these findings present evidence that 9-cis RA has a wide range of activities in human cancer models.

  4. Combinatorial Cis-regulation in Saccharomyces Species

    Directory of Open Access Journals (Sweden)

    Aaron T. Spivak

    2016-03-01

    Full Text Available Transcriptional control of gene expression requires interactions between the cis-regulatory elements (CREs controlling gene promoters. We developed a sensitive computational method to identify CRE combinations with conserved spacing that does not require genome alignments. When applied to seven sensu stricto and sensu lato Saccharomyces species, 80% of the predicted interactions displayed some evidence of combinatorial transcriptional behavior in several existing datasets including: (1 chromatin immunoprecipitation data for colocalization of transcription factors, (2 gene expression data for coexpression of predicted regulatory targets, and (3 gene ontology databases for common pathway membership of predicted regulatory targets. We tested several predicted CRE interactions with chromatin immunoprecipitation experiments in a wild-type strain and strains in which a predicted cofactor was deleted. Our experiments confirmed that transcription factor (TF occupancy at the promoters of the CRE combination target genes depends on the predicted cofactor while occupancy of other promoters is independent of the predicted cofactor. Our method has the additional advantage of identifying regulatory differences between species. By analyzing the S. cerevisiae and S. bayanus genomes, we identified differences in combinatorial cis-regulation between the species and showed that the predicted changes in gene regulation explain several of the species-specific differences seen in gene expression datasets. In some instances, the same CRE combinations appear to regulate genes involved in distinct biological processes in the two different species. The results of this research demonstrate that (1 combinatorial cis-regulation can be inferred by multi-genome analysis and (2 combinatorial cis-regulation can explain differences in gene expression between species.

  5. Small RNAs and the regulation of cis-natural antisense transcripts in Arabidopsis

    Directory of Open Access Journals (Sweden)

    Lonardi Stefano

    2008-01-01

    Full Text Available Abstract Background In spite of large intergenic spaces in plant and animal genomes, 7% to 30% of genes in the genomes encode overlapping cis-natural antisense transcripts (cis-NATs. The widespread occurrence of cis-NATs suggests an evolutionary advantage for this type of genomic arrangement. Experimental evidence for the regulation of two cis-NAT gene pairs by natural antisense transcripts-generated small interfering RNAs (nat-siRNAs via the RNA interference (RNAi pathway has been reported in Arabidopsis. However, the extent of siRNA-mediated regulation of cis-NAT genes is still unclear in any genome. Results The hallmarks of RNAi regulation of NATs are 1 inverse regulation of two genes in a cis-NAT pair by environmental and developmental cues and 2 generation of siRNAs by cis-NAT genes. We examined Arabidopsis transcript profiling data from public microarray databases to identify cis-NAT pairs whose sense and antisense transcripts show opposite expression changes. A subset of the cis-NAT genes displayed negatively correlated expression profiles as well as inverse differential expression changes under at least one of the examined developmental stages or treatment conditions. By searching the Arabidopsis Small RNA Project (ASRP and Massively Parallel Signature Sequencing (MPSS small RNA databases as well as our stress-treated small RNA dataset, we found small RNAs that matched at least one gene in 646 pairs out of 1008 (64% protein-coding cis-NAT pairs, which suggests that siRNAs may regulate the expression of many cis-NAT genes. 209 putative siRNAs have the potential to target more than one gene and half of these small RNAs could target multiple members of a gene family. Furthermore, the majority of the putative siRNAs within the overlapping regions tend to target only one transcript of a given NAT pair, which is consistent with our previous finding on salt- and bacteria-induced nat-siRNAs. In addition, we found that genes encoding plastid- or

  6. Opinions on Marijuana: Sex Differences at a Western Canadian University

    Science.gov (United States)

    Taylor, Hugh

    1972-01-01

    College freshmen were surveyed to determine their opinions regarding marijuana. Analysis of the data showed that male students in all cases were ahead of female students in exploring the marijuana sub-culture. The data provides a basis for judging future trends in this controversial area of student life. (Author)

  7. Effects of cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid (CLA) isomers on immune function in healthy men

    NARCIS (Netherlands)

    Albers, R.; Wielen, R.P.J. van der; Brink, E.J.; Hendriks, H.F.J.; Dorovska-Taran, V.N.; Mohede, I.C.M.

    2003-01-01

    Objectives: To study the effects of two different mixtures of the main conjugated linoleic acid (CLA) isomers cis-9, trans-11 CLA and trans-10, cis-12 CLA on human immune function. Design: Double-blind, randomized, parallel, reference-controlled intervention study. Subjects and intervention:

  8. The North American opinion climate for nanotechnology and its products: Opportunities and challenges

    International Nuclear Information System (INIS)

    Priest, Susanna

    2006-01-01

    A January 2005 telephone survey of 1200 people in the U.S. and 2000 Canadians provides a snapshot of current North American opinion regarding nanotechnology at this crucial early point in its emergence from the laboratory to the arena of public discourse and public understanding. Using a typology of 'publics' developed through analysis of a previous comparative survey (Priest, S., 2006) and subsequently tested against these newer data (Priest, S., 2005) this article describes the opinion climate for nanotechnology across North America. The comparison of key results from the two countries helps illustrate how social and cultural differences contribute to reactions to new technologies, including nanotech. The article also discusses implications for nanotechnology-related public outreach and risk communication efforts

  9. The association between money and opinion in academic emergency medicine.

    Science.gov (United States)

    Birkhahn, Robert H; Blomkalns, Andra; Klausner, Howard; Nowak, Richard; Raja, Ali S; Summers, Richard; Weber, Jim E; Briggs, William M; Arkun, Alp; Diercks, Deborah

    2010-05-01

    Financial conflicts of interest have come under increasing scrutiny in medicine, but their impact has not been quantified. Our objective was to use the results of a national survey of academic emergency medicine (EM) faculty to determine if an association between money and personal opinion exists. We conducted a web-based survey of EM faculty. Opinion questions were analyzed with regard to whether the respondent had either 1) received research grant money or 2) received money from industry as a speaker, consultant, or advisor. Responses were unweighted, and tests of differences in proportions were made using Chi-squared tests, with pmoney. Respondents with research money were more likely to be comfortable accepting gifts (40% vs. 29%) and acting as paid consultants (50% vs. 37%). They had a more favorable attitude with regard to societal interactions with industry and felt that industry-sponsored lectures could be fair and unbiased (52% vs. 29%). Faculty with fee-for-service money mirrored those with research money. They were also more likely to believe that industry-sponsored research produces fair and unbiased results (61% vs. 45%) and less likely to believe that honoraria biased speakers (49% vs. 69%). Accepting money for either service or research identified a distinct population defined by their opinions. Faculty engaged in industry-sponsored research benefitted socially (collaborations), academically (publications), and financially from the relationship.

  10. Class Teacher Candidates' Opinions on Genetically Modified Organisms (GMO)

    Science.gov (United States)

    Ural Keles, Pinar; Aydin, Suleyman

    2017-01-01

    This study was conducted to determine the Class teacher candidates' opinions on Genetically Modified Organisms. The study was carried out with 101 teacher candidates who were studying in the 3rd grade of Agri Ibrahim Çeçen University Classroom Teacher Department in 2016-2017 academic year. Of the students who participated in the survey, 56 were…

  11. The Food Service Worker and the Travis Air Force Base Experimental Food System: Worker Opinion and Job Satisfaction

    Science.gov (United States)

    1975-04-01

    Surveys and interviews were administered to both civilian and military food service workers at Travis Air Force Base, both before and after dining system changes, to assess job satisfaction, opinions about additional training, and opinions about environmental and equipment features relevant to potential human factors problems.

  12. Effects of pyrethroid pesticide cis-bifenthrin on lipogenesis in hepatic cell line.

    Science.gov (United States)

    Xiang, Dandan; Chu, Tianyi; Li, Meng; Wang, Qiangwei; Zhu, Guonian

    2018-06-01

    Mounting evidence suggests there is a link between exposure to synthetic pyrethroids (SPs) and the development of obesity. The information presented in this study suggests that cis-bifenthrin (cis-BF) could activate pregnane X receptor (PXR) mediated pathway and lead to the lipid accumulation of human hepatoma (HepG2) cells. Cells were incubated in the control or different concentrations of cis-BF for 24 h. The 1 × 10 -7  M and 1 × 10 -6  M cis-BF exposure were found to induce cellular triglyceride (TG) accumulation significantly. This phenomenon was further supported by Oil Red O Staining assay. The cis-BF exposure caused upregulation of PXR gene and protein. Correspondingly, we also observed the increased expression of downstream genes involved in lipid formation and the inhibition of the expression of β-oxidation. As chiral pesticide,cis-BF was further conformed to behave enantioselectivity in the lipid metabolism. Rather than 1R-cis-BF, HepG2 cells incubated with 1S-cis-BF exhibited a significant TG accumulation. 1S-cis-BF also showed a higher binding level, of which the KD value was 9.184 × 10 -8  M in the SPR assay, compared with 1R-cis-BF (3.463 × 10 -6  M). In addition, the molecular docking simulation analyses correlated well with the KD values measured by the SPR, indicating that 1S-cis-BF showed a better binding affinity with PXR. The results in this study also elucidates the differences between the two enantiomers of pyrethroid-induced toxicity in lipid metabolism of non-target organism. Copyright © 2018 Elsevier Ltd. All rights reserved.

  13. Does the weather influence public opinion about climate change?

    Science.gov (United States)

    Donner, S. D.; McDaniel, J.

    2010-12-01

    Public opinion in North America about the science of anthropogenic climate change and the motivation for policy action has been variable over the past twenty years. The trends in public opinion over time have been attributed the general lack of pressing public concern about climate change to a range of political, economic and psychological factors. One driving force behind the variability in polling data from year to year may be the weather itself. The difference between what we “expect” - the climate - and what we “get” - the weather - can be a major source of confusion and obfuscation in the public discourse about climate change. For example, reaction to moderate global temperatures in 2007 and 2008 may have helped prompt the spread of a “global cooling” meme in the public and the news media. At the same time, a decrease in the belief in the science of climate change and the need for action has been noted in opinion polls. This study analyzes the relationship between public opinion about climate change and the weather in the U.S. since the mid-1980s using historical polling data from several major organizations (e.g. Gallup, Pew, Harris Interactive, ABC News), historical monthly air temperature (NCDC) and a survey of opinion articles from major U.S. newspapers (Washington Post, New York Times, Wall Street Journal, Houston Chronicle, USA Today). Seasonal and annual monthly temperature anomalies for the northeastern U.S and the continental U.S are compared with available national opinion data for three general categories of questions: i) Is the climate warming?, ii) Is the observed warming due to human activity?, and iii) Are you concerned about climate change? The variability in temperature and public opinion over time is also compared with the variability in the fraction of opinion articles in the newspapers (n ~ 7000) which express general agreement or disagreement with IPCC Summary for Policymakers consensus statements on climate change (“most of

  14. New energy opinion leaders' lifestyles and media usage - applying data mining decision tree analysis for UNIDO - ICHET web site users

    International Nuclear Information System (INIS)

    Tsai, M.; Veziroglu, A.; Warren, S.; Que, Y.

    2007-01-01

    According to the innovation diffusion research, the innovators, opinion leaders, and diffusion agents play vital roles in promoting the acceptance of innovation. The innovators and opinion leaders must be able to cope with the high degree of uncertainty about an innovation and usually they have higher innovation-related media usage than the majority. Based on consumer behavior studies, lifestyle analysis could help researchers divide consumers into different lifestyle groups to understand and predict consumer behaviors. Lifestyle allows researchers to investigate consumers via their activities, interests and opinions instead of using demographic variables. The purpose of this research is to investigate how new energy innovators and opinion leaders' different lifestyles affect their new energy product adoption, and their media usage regarding new energy reports or promotion. In order to achieve the purposes listed above, the researchers need to locate and contact the potential innovators and opinion leaders in this field. Thus the researchers cooperate with UNIDO-ICHET to launch this survey. This cross-discipline online survey was formally launched from Aug 2005 to Oct 2006. The result of this survey successfully collected 2040 new energy innovators and opinion leaders' information. The researchers analyzed the data using SPSS statistics software and Data Mining decision tree analysis. Then the researchers divided new energy innovators into four groups: social-oriented, young modern, conservative, and show-off-oriented. They also analyzed which lifestyle groups are better targets for innovation agencies to launch innovation-related promotions or campaigns

  15. Dental Sealants: Knowledge, Value, Opinion, and Practice among Dental Professionals of Bathinda City, India

    OpenAIRE

    Asawa, Kailash; Gupta, Vivek V.; Tak, Mridula; Nagarajappa, Ramesh; Chaturvedi, Pulkit; Bapat, Salil; Mishra, Prashant; Roy, Santanu Sen

    2014-01-01

    Objective. The purpose of the study was to assess the knowledge, value, opinion, and practice regarding use of dental sealants among private dental practitioners in Bathinda City, Punjab, India. Materials and Methods. A cross-sectional survey was conducted among all private dental practitioners in Bathinda City, Punjab. A self-administered structured questionnaire consisting of 28 items was used to assess their knowledge, value, opinion, and practice regarding dental sealants. One-way analysi...

  16. Opinion and Persuasion

    OpenAIRE

    Ioan Constantin Dima; Daniela Gîfu

    2014-01-01

    The research proves that persuasion has two types of objectives. Its main objective is the change of opinion. Its fundamental and foundational objectives are the change in attitude, generic conduct and situational behaviour. The main objective controls the fundamental objectives. The change in attitudes and conduct/behaviour is presided by changes in opinion. Persuasion is thus shown to be primarily and ultimately a matter of opinion. As such, its mechanism to manage and generate ...

  17. Public-opinion poll on energy saving

    International Nuclear Information System (INIS)

    1982-01-01

    A public-opinion poll was carried out on energy saving from November 26 to December 2, 1981, across the country. The number of persons participated in the survey was 5,000, whose age was 20 and above. The recovery ratio was 4,007 persons (80.1 %). The results of the survey and also the question-answer form are given with respective percentages. The questions were in the following three categories: (1) cognizance of energy saving - space-heating temperature, energy saving conscience use of private cars, purchase of highenergy consumption appliances; (2) energy for future - energy consumption, energy consumption trend, new types of energy, main sources of power generation, nuclear power in the overall electric power, apprehension toward nuclear power plants, safety measures in nuclear power plants; (3) governmental energy policy measures. (J.P.N.)

  18. U.S./CIS eye joint nuclear rocket venture

    Science.gov (United States)

    Clark, John S.; Mcilwain, Melvin C.; Smetanikov, Vladimir; D'Yakov, Evgenij K.; Pavshuk, Vladimir A.

    1993-01-01

    An account is given of the significance for U.S. spacecraft development of a nuclear thermal rocket (NTR) reactor concept that has been developed in the (formerly Soviet) Commonwealth of Independent States (CIS). The CIS NTR reactor employs a hydrogen-cooled zirconium hydride moderator and ternary carbide fuels; the comparatively cool operating temperatures associated with this design promise overall robustness.

  19. Opinion dynamics in activity-driven networks

    Science.gov (United States)

    Li, Dandan; Han, Dun; Ma, Jing; Sun, Mei; Tian, Lixin; Khouw, Timothy; Stanley, H. Eugene

    2017-10-01

    Social interaction between individuals constantly affects the development of their personal opinions. Previous models such as the Deffuant model and the Hegselmann-Krause (HK) model have assumed that individuals only update their opinions after interacting with neighbors whose opinions are similar to their own. However, people are capable of communicating widely with all of their neighbors to gather their ideas and opinions, even if they encounter a number of opposing attitudes. We propose a model in which agents listen to the opinions of all their neighbors. Continuous opinion dynamics are investigated in activity-driven networks with a tolerance threshold. We study how the initial opinion distribution, tolerance threshold, opinion-updating speed, and activity rate affect the evolution of opinion. We find that when the initial fraction of positive opinion is small, all opinions become negative by the end of the simulation. As the initial fraction of positive opinions rises above a certain value —about 0.45— the final fraction of positive opinions sharply increases and eventually equals 1. Increased tolerance threshold δ is found to lead to a more varied final opinion distribution. We also find that if the negative opinion has an initial advantage, the final fraction of negative opinion increases and reaches its peak as the updating speed λ approaches 0.5. Finally we show that the lower the activity rate of individuals, the greater the fluctuation range of their opinions.

  20. Opinions of Female Juvenile Delinquents on Language-Based Literacy Activities

    Science.gov (United States)

    Sanger, Dixie; Ritzman, Mitzi; Stremlau, Aliza; Fairchild, Lindsey; Brunken, Cindy

    2009-01-01

    A mixed methods study was conducted to examine female juvenile delinquents' opinions and reactions on nine language-based literacy activities. Forty-one participants ranging in age from 13 to 18 years responded to a survey consisting of nine multiple-choice items and one open-ended question concerning the usefulness of activities. Quantitative and…

  1. [Regulatory policies and public opinion: the case of smoking].

    Science.gov (United States)

    Saltó, Esteve; Joan R, Villalbí; Valverde, Araceli; Baranda, Lucía; Plasencia, Antoni

    2006-01-01

    Collecting and disseminating information about the public opinion on a regulatory process gives visibility to the silent social support and facilitates the process, which often confronts resistance from interest groups. This paper presents a survey about a proposed legislation on tobacco in its final stages and its results, and some considerations on the use of this sort of information in change processes. Cross sectional descriptive study. In December 2005 a brief telephone survey was made to a population sample of 18 and more years of age (N=830) in Catalonia (Spain). The questionnaire explored opinions on the proposed regulations under discussion. We present the degree of support and the rating of nine regulatory measures, stratified by the respondents use of tobacco. Daily smokers are 26.3% of the surveyed population. Awareness and general support for tobacco regulation are very high. Aspects with wider support include bans on sales to minors (97.3%), smoking in enclosed public places (92.8%) and workplaces (89%), and publicity (90.8%). The aspect with less social support is banning smoking in bars and cafes (80.2%). The population supports widely tobacco regulation. This reinforces the process and weakens the arguments of those against it. Although smokers are less supportive, most of them accept the regulations, except for limitations in bars and cafes.

  2. Cis By Trans

    OpenAIRE

    Rodovalho,Amara Moira

    2017-01-01

    Cis, trans: above all, metaphors. Cisjordan, region skirting the Jordan River. Cisplatin, Uruguay’s ancient name, region occupying one of the banks of the Prata River. Trans- Amazonian, that which crosses the Amazon; transatlantic, that which crosses the Atlantic. Cisalpine, transalpine. The geometric isomerism of Organic Chemistry, where “cis” are atoms that, when molecules are divided in half, remain on the same side, and “trans” those remaining on opposite sides. Ev...

  3. Perceived risk and benefit of nuclear waste repositories: four opinion clusters.

    Science.gov (United States)

    Seidl, Roman; Moser, Corinne; Stauffacher, Michael; Krütli, Pius

    2013-06-01

    Local public resistance can block the site-selection process, construction, and operation of nuclear waste repositories. Social science has established that the perception of risks and benefits, trust in authorities, and opinion on nuclear energy play important roles in acceptance. In particular, risk and benefit evaluations seem critical for opinion formation. However, risks and benefits have rarely been studied independently and, most often, the focus has been on the two most salient groups of proponents and opponents. The aim of this exploratory study is to examine the often-neglected majority of people holding ambivalent or indifferent opinions. We used cluster analysis to examine the sample (N = 500, mailed survey in German-speaking Switzerland) in terms of patterns of risk and benefit perception. We reveal four significantly different and plausible clusters: one cluster with high-benefit ratings in favor of a repository and one cluster with high-risk ratings opposing it; a third cluster shows ambivalence, with high ratings on both risk and benefit scales and moderate opposition, whereas a fourth cluster seems indifferent, rating risks and benefits only moderately compared to the ambivalent cluster. We conclude that a closer look at the often neglected but considerable number of people with ambivalent or indifferent opinions is necessary. Although the extreme factions of the public will most probably not change their opinion, we do not yet know how the opinion of the ambivalent and indifferent clusters might develop over time. © 2012 Society for Risk Analysis.

  4. Fatigued and drowsy driving: a survey of attitudes, opinions and behaviors.

    Science.gov (United States)

    Vanlaar, Ward; Simpson, Herb; Mayhew, Dan; Robertson, Robyn

    2008-01-01

    There is evidence suggesting that the problem of fatigued or drowsy driving is an important contributor to road crashes. However, not much is known about public perceptions of the issue. The purpose of this study was to obtain information on attitudes, opinions, and professed practices related to fatigued or drowsy driving. The data were gathered by means of a public opinion poll among a representative sample of 750 Ontario drivers. A majority of drivers (58.6%) admitted that they occasionally drive while fatigued or drowsy. Of greater importance, 14.5% of respondents admitted that they had fallen asleep or "nodded off" while driving during the past year. Nearly 2% were involved in a fatigue or drowsy driving related crash in the past year. Respondents were also asked about measures they take to overcome fatigue or drowsiness. Results indicate that relatively ineffective measures such as opening the window or playing music are the most popular; the most effective preventive measure--taking a rest--is the least popular. The prevalence of the behavior, coupled with the ineffective prevention measures favored by the public suggest there is a need for increasing their level of awareness and knowledge about the problem. Results from this study further emphasize the importance of increasing the fatigued and drowsy driving knowledge base and the need to educate the public about it.

  5. Elementary School Parents' Opinions toward Educational Technology and Its Role in Their Children's Education

    Science.gov (United States)

    Biddle, Kevin J.

    2013-01-01

    This study surveyed parents of elementary students in the small Midwestern community of Montpelier, Indiana to elicit their opinions toward the educational technology in their children's school and the role it plays in their education. Montpelier Elementary School (MES) has 223 students from 161 families. A phone survey was done to which about 42%…

  6. Employee benefits managers' opinions about addiction treatment.

    Science.gov (United States)

    McFarland, Bentson H; Lierman, Walter K; Penner, Norman R; McCamant, Lynn E; Zani, Brigid G

    2003-01-01

    Employee benefits managers arrange addictive disease treatment insurance coverage for the majority of people in the United States but little is known about these decision-makers. Managers were surveyed to learn their opinions about addiction treatment. Subjects were 131 people (61 percent female, 94 percent white, average age 46, average of 14 years in the human resources field). Managers were asked to rank health benefits (physical health, dental, alcohol-drug, vision, mental health, employee assistance program, and pharmaceuticals) on 15 dimensions. Managers ranked alcohol-drug abuse treatment worst on fiveitems and second to the worst on another four of the 15 dimensions. On the item considered most important by the managers, respondents noted that employees often (2.8) ask for improved physical health benefits but rarely do so for alcohol and drug (4.1) benefits (p < .001). Education of workers and payers will be needed to change opinions about treatment of addictive disorders.

  7. Communications and Information Sharing (CIS) Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — TheCommunications and Information Sharing (CIS) Laboratory is a Public Safety interoperable communications technology laboratory with analog and digital radios, and...

  8. Public opinion towards castration without anaesthesia and lack of access to pasture in beef cattle production.

    Science.gov (United States)

    Lemos Teixeira, Dayane; Larraín, Rafael; Melo, Oscar; Hötzel, María José

    2018-01-01

    Recent publications have shown that citizens in developing nations are gaining interest in farm animal welfare. The aims of this study were to assess the opinion of Chilean citizens about surgical castration without anaesthesia and lack of access to pasture in beef cattle production, to investigate how involvement in livestock production influences opinions, and to evaluate if different types of information would affect their opinion towards these management practices. The study was carried out in the Metropolitan Region of Santiago, Chile, and consisted of two surveys with 400 participants in each study. The first one used an online, self-administered questionnaire and the second one used a face to face questionnaire. The second questionnaire had four information treatments assigned randomly to survey participants (no information; negative information; negative and positive information; positive information). Most participants were aware that the two management practices are common in beef production systems and were opposed to them. Involvement in animal production was associated with greater acceptance of both management practices and participants that had visited a beef production farm before the study were more likely to support castration without anaesthesia in Survey 1. Belonging to any socioeconomic group and providing negative or positive information had no impact on participants' opinion. The results show a disconnection between the views of participants recruited for this study and beef production systems that do not provide pain control for male cattle surgical castration or provide little or no access to pasture.

  9. EIA for mining projects in the CIS

    Energy Technology Data Exchange (ETDEWEB)

    Coppin, N.J.; Wheeler, P. [Wardell Armstrong, Newcastle under Lyme (United Kingdom)

    1996-12-31

    This paper examines the Environmental Impact Assessment (EIA) requirements and procedures encountered during work on gold and coal mining projects in Kazakhstan, Uzbekistan and Mongolia. Observations on the implementation of former-Soviet inspired EIA in the Commonwealth of Independent States (CIS), and the differences with North American and European requirements and procedures are highlighted, particularly where these indicate lessons for the West. The main implications for mining companies considering or developing projects in the CIS are discussed, particularly the procedures that have to be followed for environmental permitting. 2 figs.

  10. US Public Opinion on Carrying Firearms in Public Places.

    Science.gov (United States)

    Wolfson, Julia A; Teret, Stephen P; Azrael, Deborah; Miller, Matthew

    2017-06-01

    To estimate US public opinion, overall and by gun ownership status, about the public places where legal gun owners should be allowed to carry firearms. We fielded an online survey among 3949 adults, including an oversample of gun owners and veterans, in April 2015. We used cross-tabulations with survey weights to generate nationally representative estimates. Fewer than 1 in 3 US adults supported gun carrying in any of the specified venues. Support for carrying in public was consistently higher among gun owners than among non-gun owners. Overall, support for carrying in public was lowest for schools (19%; 95% confidence interval [CI] = 16.7, 21.1), bars (18%; 95% CI = 15.9, 20.6), and sports stadiums (17%; 95% CI = 15.0, 19.5). Most Americans, including most gun owners, support restricting public places legal gun owners can carry firearms. These views contrast sharply with the current trend in state legislatures of expanding where, how, and by whom guns can be carried in public. Recent state laws and proposed federal legislation that would force states to honor out-of-state concealed carry permits are out of step with American public opinion.

  11. Fukushima effects in Germany? Changes in media coverage and public opinion on nuclear power.

    Science.gov (United States)

    Arlt, Dorothee; Wolling, Jens

    2016-10-01

    Based on a literature review on factors that explain media effects and previous findings on media coverage and public opinion on nuclear power, this article examines the effects of Fukushima on media coverage and public opinion in Germany in two studies. The first study uses content analysis data to analyse changes in media coverage, and the second one is based on panel survey data to examine attitude changes on an individual level. The results of both studies show changes in media coverage and public opinion on nuclear power. Furthermore, the second study reveals that individual attitude changes cannot necessarily be explained by the same factors as the distribution of attitudes. © The Author(s) 2015.

  12. Quantification of informed opinion

    International Nuclear Information System (INIS)

    Rasmuson, D.M.

    1985-01-01

    The objective of this session, Quantification of Informed Opinion, is to provide the statistician with a better understanding of this important area. The NRC uses informed opinion, sometimes called engineering judgment or subjective judgment, in many areas. Sometimes informed opinion is the only source of information that exists, especially in phenomenological areas, such as steam explosions, where experiments are costly and phenomena are very difficult to measure. There are many degrees of informed opinion. These vary from the weatherman who makes predictions concerning relatively high probability events with a large data base to the phenomenological expert who must use his intuition tempered with basic knowledge and little or no measured data to predict the behavior of events with a low probability of occurrence. The first paper in this session provides the reader with an overview of the subject area. The second paper provides some aspects that must be considered in the collection of informed opinion to improve the quality of the information. The final paper contains an example of the use of informed opinion in the area of seismic hazard characterization. These papers should be useful to researchers and statisticians who need to collect and use informed opinion in their work

  13. Radiation is invisible but causes a change in the opinions of the people

    International Nuclear Information System (INIS)

    Kristiansen, Silje; Bonfadelli, Heinz

    2013-01-01

    The nuclear accident in Japan 2011 was followed by massive media coverage. As nuclear power is a hot political topic and news media coverage is an important factor in opinion building, it is of interest to analyse what impact the catastrophe in Fukushima and the triggered media coverage had on people's opinion on nuclear power and its risks. This article is based on a survey mandated by the Swiss Federal Nuclear Safety Inspectorate (ENSI), which was carried out one year after the nuclear accident in Fukushima. Yes, the Fukushima accident did affect people's opinion on nuclear power. Even before the accident the majority of the Swiss population was against nuclear power and after the accident the negative opinion was stronger. The trust in the authorities, science and nuclear power plant operators also suffered under Fukushima, but they did catch up quite well until one year after the accident. This also reflects that the survey participants are more worried about a nuclear accident abroad than in Switzerland. Are those results based on the accident and the following media coverage? Almost 80 % mentioned to have heard or read about nuclear power and nuclear power plants in the media, so to assume an influence is not far-fetched. However only 15 % did actively search for information about nuclear power, but the big majority did talk to others about nuclear power. Thus the media coverage triggered interest and follow-up interpersonal communication. (orig.)

  14. The IRSN 2006 barometer. The opinion on risks and security of the French population. Global results

    International Nuclear Information System (INIS)

    2006-01-01

    This report presents and comments the results of a survey during which a sample of the French population has been questioned on their current concerns (about the society, about the environment, about their opinion on industrial risks, on scientific expertise, on who should control a risky installation), the opinion on 28 risk situations (risks to which French people feel exposed, confidence in authorities, truth of information on hazards, hierarchy of the 28 situations, acceptability of installations), the opinion on the nuclear activity and industry (the nuclear risk, the credibility and expertise of interveners, and the issue of radioactive wastes and public debate)

  15. Mechanically induced cis to trans reisomerization of azobenzene

    Science.gov (United States)

    Turansky, Robert; Konopka, Martin; Stich, Ivan; Marx, Dominik

    2007-03-01

    Using density functional techniques we study mechanochemistry of the azobenzene molecule. Azobenzene is an optically switchable molecule. Laser light is normally used to achieve molecular switching between the cis and trans isomers. We use mechanochemistry to achieve the switching. Thiolate-gold bond can used to exert mechanical energy on the molecule bonded between two gold electrodes in static AFM apparatus. Our model consists of two realistic gold electrodes bridged by dithioazobenzene. We find that pulling the transisomer leads just to formation of gold nanowires and mechanical breakage of the electrodes. However, mechanochemistry with modest applied forces leads to cis trans reisomerization via rotation mechanism. Contrary, use of simple constraints instead of realistic gold electrodes, leads to cis trans reisomerization, albeit with significantly larger applied forces and via inversion mechanism. Important experimental and theoretical ramifications of these simulations will be discussed.

  16. Opinion Integration and Summarization

    Science.gov (United States)

    Lu, Yue

    2011-01-01

    As Web 2.0 applications become increasingly popular, more and more people express their opinions on the Web in various ways in real time. Such wide coverage of topics and abundance of users make the Web an extremely valuable source for mining people's opinions about all kinds of topics. However, since the opinions are usually expressed as…

  17. The effect of cis-diammine dichloro platinum(II) on radiation injury in the rat bowel

    International Nuclear Information System (INIS)

    Lee, Kyung Ja; Rhee, Chung Sik

    1995-01-01

    This experimental study was performed for evaluate the effects of cis-diamminedichloroplatinum(II) (cis-DDP) on the radiation injury of rat bowel by histopathologic changes. Rats were exposed to entire abdomen by a single doses of X-ray(6-10 Gy) without or with cis-DDP(2.5mg/kg). Rats were divided into 3 groups such as radiation alone, cis-DDP alone and combined group. In combined group, cis-DDP was given 30 minutes before or immediately after irradiation. Cis-DDP induced the inflammatory cell infiltrations with focal necrosis of the mucosa in the small bowel and no abnormal change in the large bowel. In radiation alone group, mucosal necrosis, submucosal fibrosis and muscular necrosis were prominent changes in small bowel and submucosal fibrosis in the large bowel. The submucosal fibrosis in the small bowel was appeared in 10 Gy of radiation alone group and 8 Gy of cis-DDP infusion after radiation and 6 Gy of cis-DDP infusion before radiation of combined group. In the large bowel, submucosal fibrosis was noted in 8 Gy of radiation alone group 8 Gy of cis-DDP infusion after radiation and 6 Gy of cis-DDP infusion before radiation of combined group. In the small bowel, the enhancement ratio was 1.67 in a group of cis-DDP infusion before radiation and 1.25 in group of cis-DDP infusion after radiation as the end point was the submucosal fibrosis. In the large bowel, the enhancement ratio was 1.33 in a group of cis-DDP infusion before radiation and 1.0 in a group of cis-DDP infusion after radiation as the end point was the submucosal fibrosis. This study suggested that cis-DDP enhance the radiation effect in the small and large bowel especially when cis-DDP was infused before radiation

  18. Oxidation reactions of derivatives of cis-octalins promoted by thallium trinitrate (TTN); Reacoes de oxidacao de cis-octalinas promovidas por trinitrato de talio (TTN)

    Energy Technology Data Exchange (ETDEWEB)

    Ferraz, Helena M.C.; Carneiro, Vania M.T.; Vieira, Tiago O.; Silva Junior, Luiz F. [Universidade de Sao Paulo (USP), SP (Brazil). Inst. de Quimica]. E-mail: luizfsjr@iq.usp.br

    2008-07-01

    The reaction of ten cis-octalins and cis-octalones with thallium trinitrate (TTN) leads to different products, depending mainly on the substitution pattern of the substrate. Functionalized cis-hydrindanes were obtained from the reaction of 1,2,3,4,4a,5,8,8a-octahydro- 4a-methylnaphthalene and of 1,2,3,4,4a,5,8,8a-octahydro-4a,7-dimethylnaphthalene with TTN in acetonitrile, whereas a cyclic ether was formed treating 1,2,3,4,4a,5,8,8a-octahydro-6,8a-dimethylnaphthalene-1-ol with TTN in trimethylorthoformate (TMOF). (author)

  19. The mediating role of emotions: News framing effects on opinions about immigration

    NARCIS (Netherlands)

    Lecheler, S.; Bos, L.; Vliegenthart, R.

    2015-01-01

    Emotions play an important role in explaining why news framing has effects on opinions about immigration. Yet, our knowledge regarding which emotions are relevant for different types of news frames is limited. This survey experiment (N = 715) determines to what extent positive and negative emotions

  20. Issue-Relevant Values and Opinions About Gay Rights: Beyond Equality and Morality.

    Science.gov (United States)

    Rhodebeck, Laurie

    2018-01-01

    Although many studies have examined the role of values in shaping public opinion, the number of values that inform this research is limited. This article employs the concept of issue-relevant values as a means to explore the broader range of values associated with policy issues. After discussing the concept in general terms, the article explores issue-relevant values pertinent to public opinion about gay rights. Using the policy examples of employment nondiscrimination and same-sex couple adoption, the present study identifies, measures, and assesses several values that add to the very short list previously used to explain public opinion about gay rights issues. Content from interest-group Web sites and news media coverage of the two issues aided in identifying the values. Data from an original Internet survey yield valid measures of the values. Multivariate analyses indicate that the values behave in predictable ways: they are strongly influenced by partisanship, and they strongly affect opinions about the two issues. The performance of the values is consistent with findings from previous research on the partisan basis of values and the value-based nature of opinions. The article concludes with suggestions for further empirical and theoretical work that could apply and extend the concept of issue-relevant values.

  1. Opinion of gastroenterologists towards quality assurance in endoscopy.

    Science.gov (United States)

    de Jonge, Vincent; Kuipers, Ernst J; van Leerdam, Monique E

    2011-03-01

    Quality assurance has become an important issue. Many societies are adopting quality assurance programs in order to monitor and improve quality of care. To assess the opinion of gastroenterologists towards quality assurance on the endoscopy department. A survey was sent to all gastroenterologists (n=319) in the Netherlands. It assessed their opinion on a quality assurance program for endoscopy units, including its design, logistics, and content. 200 gastroenterologists (63%) completed the questionnaire. 95% had a positive opinion towards quality assurance and 67% supposed an increase in quality. 28% assumed a negative impact on the time available for patient contact by introducing a quality assurance program and 35% that the capacity would decrease. A negative attitude towards disclosure of results to insurance companies (23%) and media (53%) was reported. Female gastroenterologists were less positive to share the results with other stakeholders (pquality measurements were assessment of complications (97%), standardised reporting (96%), and adequate patient information (95%). Gastroenterologists have a positive attitude towards quality assurance. However, concerns do exist about time investment and disclosure of results to others. Information provision and procedure characteristics were considered the most important aspects of quality assurance. Copyright © 2010 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  2. Personal Perceptions and Perceived Public Opinion About Stuttering in the United States: Implications for Anti-Stigma Campaigns.

    Science.gov (United States)

    Boyle, Michael P

    2017-08-15

    This exploratory study was the first to obtain quantitative and qualitative data on both personal perceptions and perceived public opinion about stuttering in order to identify topics to include in anti-stigma programs for stuttering. Three-hundred ten adults in the United States completed a web survey that assessed knowledge about stuttering and attitudes toward people who stutter (PWS) with questions addressing personal perceptions (direct questions) and perceived public opinion (indirect questions). Many participants reported favorable personal perceptions of PWS regarding their intelligence, competence, and potential for success. However, most participants did not personally believe PWS were confident, and most believed they were shy. Perceived public opinion was more unfavorable as a majority agreed that the public is uncomfortable talking with PWS and that the public would recommend PWS avoid jobs requiring high speech demands and avoid talking to large audiences. A minority of participants agreed PWS are perceived publicly as capable or mentally healthy. The survey demonstrated misunderstandings and negative perceptions of PWS, especially when measured with perceived public opinion. Results can increase our understanding of content areas that should be included in anti-stigma programs for stuttering and highlight different methods for analyzing public perceptions of stuttering.

  3. A Study on Attitude and Opinion towards Using Computer Technology in Teaching among B.Ed. Trainees in Tiruchirappalli District

    Science.gov (United States)

    Kumar, C. Ashok

    2015-01-01

    The main aim of the study was to find out whether there was a significant difference in the attitude and opinion towards using Computer Technology in teaching among B.Ed., trainees in terms of select independent variables. Normative survey was the technique employed. Opinion towards Computer Usage and Attitude towards Computer Technology inventory…

  4. Cis-bifenthrin induces immunotoxicity in adolescent male C57BL/6 mice.

    Science.gov (United States)

    Wang, Xia; Gao, Xingli; He, Bingnan; Zhu, Jiawei; Lou, Huihui; Hu, Qinglian; Jin, Yuanxiang; Fu, Zhengwei

    2017-07-01

    Bifenthrin (BF) is an important synthetic pyrethroid. Previous studies have demonstrated that cis-BF exhibits toxic effects on development, the neurological, reproductive and endocrine system. In this study, we evaluated the immunotoxicity caused by cis-BF in adolescent male C57BL/6 mice. Mice were exposed orally to 0, 5, 10, and 20 mg/kg/d for 3 weeks. The results showed that body weight, spleen weight, and splenic cellularity decreased in mice exposed to 20 mg/kg/d cis-BF. Additionally, we found that the mRNA levels of the pro-inflammatory factors IL-1β, IL-6, CXCL-1, and TNF-α, in peritoneal macrophages, the spleen, and the thymus were inhibited in the cis-BF-treated groups. Moreover, MTT assays demonstrated that cis-BF inhibited splenocyte proliferation stimulated by LPS or Con A, as well as the secretion of IFN-γ on Con A stimulation. Collectively, the results of this study suggest that exposure to cis-BF has the potential to induce immunotoxicity in adolescent male C57BL/6 mice. © 2017 Wiley Periodicals, Inc.

  5. Evolving Trends in Public Opinion on the Quality of Local Schools

    Science.gov (United States)

    Bali, Valentina A.

    2016-01-01

    The ratings given by citizens to local public schools in the United States have been rising in the last decades. Using national public opinion surveys, this study seeks to understand the determinants of public evaluations of local schools across time. Aggregate trend analyses indicate that public evaluations of local schools are influenced not…

  6. Your opinion counts

    CERN Multimedia

    2009-01-01

    The Human Resources Department will soon be launching an opinion poll for CERN staff members In his message to the CERN personnel, the new Director-General said "My New Year’s resolution involves managing CERN in a participative, democratic and inclusive manner". In the same spirit, the Human Resources (HR) Department plans to develop new channels of communication with CERN personnel. Dialogue is not always easy in an organization the size of CERN and, with this, its first survey, HR hopes to contribute towards it. In March this year, the HR Department will be sending an on-line questionnaire to all staff, giving you the opportunity to comment on your personal experiences of working life at CERN, your expectations and your commitment to the Organization. The initiative is the brainchild of the Head of the HR Department, Enrico Chiaveri, and the Deputy Department Head, Anne-Sylvie Catherin. A...

  7. Chefs' opinions of restaurant portion sizes.

    Science.gov (United States)

    Condrasky, Marge; Ledikwe, Jenny H; Flood, Julie E; Rolls, Barbara J

    2007-08-01

    The objectives were to determine who establishes restaurant portion sizes and factors that influence these decisions, and to examine chefs' opinions regarding portion size, nutrition information, and weight management. A survey was distributed to chefs to obtain information about who is responsible for determining restaurant portion sizes, factors influencing restaurant portion sizes, what food portion sizes are being served in restaurants, and chefs' opinions regarding nutrition information, health, and body weight. The final sample consisted of 300 chefs attending various culinary meetings. Executive chefs were identified as being primarily responsible for establishing portion sizes served in restaurants. Factors reported to have a strong influence on restaurant portion sizes included presentation of foods, food cost, and customer expectations. While 76% of chefs thought that they served "regular" portions, the actual portions of steak and pasta they reported serving were 2 to 4 times larger than serving sizes recommended by the U.S government. Chefs indicated that they believe that the amount of food served influences how much patrons consume and that large portions are a problem for weight control, but their opinions were mixed regarding whether it is the customer's responsibility to eat an appropriate amount when served a large portion of food. Portion size is a key determinant of energy intake, and the results from this study suggest that cultural norms and economic value strongly influence the determination of restaurant portion sizes. Strategies are needed to encourage chefs to provide and promote portions that are appropriate for customers' energy requirements.

  8. Current opinion on clip placement after breast biopsy: A survey of practising radiologists in France and Quebec

    International Nuclear Information System (INIS)

    Thomassin-Naggara, I.; Jalaguier-Coudray, A.; Chopier, J.; Tardivon, A.; Trop, I.

    2013-01-01

    Aim: To investigate current practice regarding clip placement after breast biopsy. Materials and methods: In June 2011, an online survey instrument was designed using an Internet-based survey site ( (www.surveymonkey.com)) to assess practices and opinions of breast radiologists regarding clip placement after breast biopsy. Radiologists were asked to give personal practice data, describe their current practice regarding clip deployment under stereotactic, ultrasonographic, and magnetic resonance imaging (MRI) guidance, and describe what steps are taken to ensure quality control with regards to clip deployment. Results: The response rate was 29.9% in France (131 respondents) and 46.7% in Quebec (50 respondents). The great majority of respondents used breast markers in their practice (92.1% in France and 96% in Quebec). In both countries, most reported deploying a clip after percutaneous biopsy under stereotactic or MRI guidance. Regarding clip deployment under ultrasonography, 38% of Quebec radiologists systematically placed a marker after each biopsy, whereas 30% of French radiologists never placed a marker in this situation, mainly due to its cost. Finally, 56.4% of radiologists in France and 54% in Quebec considered that their practice regarding clip deployment after breast percutaneous biopsy had changed in the last 5 years. Conclusion: There continues to be variations in the use of biopsy clips after imaging-guided biopsies, particularly with regards to sonographic techniques. These variations are likely to decrease over time, with the standardization of relatively new investigation protocols

  9. Complex pharmaceutical care intervention in pulmonary care Part B. Patient opinion and process survey

    NARCIS (Netherlands)

    Stuurman-Bieze, A.GG; Kokenberg, M.E.A.P.; Tobi, H; de Boer, W.O.; van Doormaal, Jasperien E.; de Jong-van den Berg, Lolkje Theodora Wilhelmina; Tromp, Th.F.J.

    2005-01-01

    Objective: The IPMP study (Interventions on the principle of Pulmonary Medication Profiles) investigates and describes the results of complex pharmaceutical care interventions provided to selected pulmonary patients to improve their drug use. This paper describes the patients' opinions about the

  10. The opinion and experiences of Dutch orthopedic surgeons and radiologists about diagnostic musculoskeletal ultrasound imaging in primary care: a survey.

    Science.gov (United States)

    Scholten-Peeters, Gwendolijne G M; Franken, Nicole; Beumer, Annechien; Verhagen, Arianne P

    2014-04-01

    The use of diagnostic musculoskeletal ultrasound (DMUS) in primary health care has increased in the recent years. Nevertheless, there are hardly any data concerning the reliability, accuracy and treatment consequences of DMUS used by physical therapists or general practitioners. Moreover, there are no papers published about how orthopedic surgeons or radiologists deal with the results of DMUS performed in primary care. Therefore, our aim is to evaluate the opinion, possible advantages or disadvantages and experiences of Dutch orthopedic surgeons and radiologists about DMUS in primary care. A cross-sectional survey in which respondents completed a self-developed questionnaire to determine their opinion, experiences, advantages, disadvantages of performing DMUS in primary care. Questionnaires were sent to 838 Dutch orthopedic surgeons and radiologists of which 213 were returned (response rate 25.4%). Our respondents saw no additional value for health care for diagnostic DMUS in primary care. DMUSs were generally repeated in secondary care. They perceived more disadvantages than advantages of performing DMUS in primary care. Mentioned disadvantages were: 'false positive results' (71.4%), 'lack of experience' (70%), 'insufficient education' (69.5%), not able to relate the outcomes of DMUS with other forms of diagnostic imaging' (65.7%), and 'false negative results' (65.3%). Radiologists and orthopedic surgeons sampled in the Netherlands show low trust in DMUS knowledge of physical therapists and general practitioners. The results should be interpreted with caution because of the small response rate and the lack of representativeness to other countries. Published by Elsevier Ltd.

  11. Determinants of attitude to volunteering in psychiatry: results of a public opinion survey in Switzerland.

    Science.gov (United States)

    Lauber, Christoph; Nordt, Carlos; Falcato, Luis; Rössler, Wulf

    2002-09-01

    The United Nations proclaimed 2001 the "International Year of Volunteers". Little is known about factors influencing the attitude to volunteering in psychiatry. However, knowledge about these factors is important as target groups to be addressed by an awareness and promotion campaign could be identified. To determine the influence of demographic, psychological and sociological factors on the attitude to volunteering in psychiatry. Multiple logistic regression analysis of the results of an opinion survey conducted on a representative population sample in Switzerland (n = 1737). Public attitude is mostly positive. It depends, however, on the form of volunteering. Two explanatory models for volunteering in psychiatry were found: first, the "antipathetic person" having social distance to and negative stereotypes towards the mentally ill. Second, the "people with social responsibility and commitment" who have former experience in volunteering, a positive attitude to community psychiatry, interest in mass media, a social profession and perceive discrimination of mentally ill persons. Age and gender are significant predictors. An awareness and promotion campaign to use the vast potential of people willing to volunteer in psychiatry can be primarily focused on those with a basic interest in social issues. Volunteering must be limited in time and responsibility. Contacting people with a positive attitude by mass media is a promising way.

  12. How does public opinion become extreme?

    Science.gov (United States)

    Ramos, Marlon; Shao, Jia; Reis, Saulo D S; Anteneodo, Celia; Andrade, José S; Havlin, Shlomo; Makse, Hernán A

    2015-05-19

    We investigate the emergence of extreme opinion trends in society by employing statistical physics modeling and analysis on polls that inquire about a wide range of issues such as religion, economics, politics, abortion, extramarital sex, books, movies, and electoral vote. The surveys lay out a clear indicator of the rise of extreme views. The precursor is a nonlinear relation between the fraction of individuals holding a certain extreme view and the fraction of individuals that includes also moderates, e.g., in politics, those who are "very conservative" versus "moderate to very conservative" ones. We propose an activation model of opinion dynamics with interaction rules based on the existence of individual "stubbornness" that mimics empirical observations. According to our modeling, the onset of nonlinearity can be associated to an abrupt bootstrap-percolation transition with cascades of extreme views through society. Therefore, it represents an early-warning signal to forecast the transition from moderate to extreme views. Moreover, by means of a phase diagram we can classify societies according to the percolative regime they belong to, in terms of critical fractions of extremists and people's ties.

  13. How does public opinion become extreme?

    Science.gov (United States)

    Ramos, Marlon; Shao, Jia; Reis, Saulo D. S.; Anteneodo, Celia; Andrade, José S.; Havlin, Shlomo; Makse, Hernán A.

    2015-05-01

    We investigate the emergence of extreme opinion trends in society by employing statistical physics modeling and analysis on polls that inquire about a wide range of issues such as religion, economics, politics, abortion, extramarital sex, books, movies, and electoral vote. The surveys lay out a clear indicator of the rise of extreme views. The precursor is a nonlinear relation between the fraction of individuals holding a certain extreme view and the fraction of individuals that includes also moderates, e.g., in politics, those who are “very conservative” versus “moderate to very conservative” ones. We propose an activation model of opinion dynamics with interaction rules based on the existence of individual “stubbornness” that mimics empirical observations. According to our modeling, the onset of nonlinearity can be associated to an abrupt bootstrap-percolation transition with cascades of extreme views through society. Therefore, it represents an early-warning signal to forecast the transition from moderate to extreme views. Moreover, by means of a phase diagram we can classify societies according to the percolative regime they belong to, in terms of critical fractions of extremists and people’s ties.

  14. C.I.S. natural gas-1

    International Nuclear Information System (INIS)

    Carson, M.; Stram, B.

    1993-01-01

    This paper reports that in the countries that make up the Commonwealth of Independent States (C.I.S.), with their vast resources and a considerable existing production base, prospects are good for further growth of the region's exportable gas surplus. Investment fundamentals are stronger for gas than for any other energy resources in the area. But the pipeline infrastructure to move large amounts of gas will need extensive refurbishment to ensure export reliability and growth. Given the potential in terms of production and markets, significant amounts of outside investment in oil, natural gas, and NGL infrastructure will likely increase dramatically in these countries in the near future. These are some of the major conclusions of Enron Corp.'s recent investigations in the C.I.S. and other former Soviet republics

  15. Expert opinion vs. empirical evidence

    OpenAIRE

    Herman, Rod A; Raybould, Alan

    2014-01-01

    Expert opinion is often sought by government regulatory agencies when there is insufficient empirical evidence to judge the safety implications of a course of action. However, it can be reckless to continue following expert opinion when a preponderance of evidence is amassed that conflicts with this opinion. Factual evidence should always trump opinion in prioritizing the information that is used to guide regulatory policy. Evidence-based medicine has seen a dramatic upturn in recent years sp...

  16. Expert opinion vs. empirical evidence

    Science.gov (United States)

    Herman, Rod A; Raybould, Alan

    2014-01-01

    Expert opinion is often sought by government regulatory agencies when there is insufficient empirical evidence to judge the safety implications of a course of action. However, it can be reckless to continue following expert opinion when a preponderance of evidence is amassed that conflicts with this opinion. Factual evidence should always trump opinion in prioritizing the information that is used to guide regulatory policy. Evidence-based medicine has seen a dramatic upturn in recent years spurred by examples where evidence indicated that certain treatments recommended by expert opinions increased death rates. We suggest that scientific evidence should also take priority over expert opinion in the regulation of genetically modified crops (GM). Examples of regulatory data requirements that are not justified based on the mass of evidence are described, and it is suggested that expertise in risk assessment should guide evidence-based regulation of GM crops. PMID:24637724

  17. How HE (Hydrogen Energy) Knowledge and Innovativeness Affect Potential Innovators' Acceptance and Opinions Regarding HE An example from UNIDO-ICHET Web-site Users

    International Nuclear Information System (INIS)

    Mavis Tsai; Scott Warren; Reide Song; JingYi Gao

    2006-01-01

    According to innovation diffusion research, the innovators, opinion leaders, and diffusion agents play vital roles in promoting the acceptance of innovation. The purpose of this research is to investigate how HE innovators' knowledge affects their acceptance and opinions about HE and related products. The research method is an on-line survey and the sample is a voluntary sample. This survey successfully collected 1126 HE innovators' information. The researchers used SPSS statistics software to analyze the data and found the relationship between HE innovators' demographics, their knowledge about hydrogen energy, their innovativeness, and their familiarity with new energy technology with their acceptance and opinions about HE, and how they use the UNIDO-ICHET web-site. The researchers found HE knowledge could be used to predict new energy innovators' information resource usage, innovativeness, new energy product adoption and their opinions about HE. (authors)

  18. Synthesis of racemic [methyl-d3]-labeled cis- and trans-3'-hydroxycotinine

    International Nuclear Information System (INIS)

    Ravard, A.; Crooks, P.A.

    1994-01-01

    A method is described for the synthesis of the racemic [methyl-d 3 ] forms of the nicotine metabolites cis-3'-hydroxycotinine and trans-3'-hydroxycotinine. The key intermediate was [methyl-d 3 ]-N-methylhydroxylamine, obtained from a selective hydrogenation of d 3 -nitro-methane. This intermediate was converted to [methyl-d 3 ]-α-3-pyridyl-N-methylnitrone, which was condensed with methyl acrylate to give a mixture of isomeric isoxazolidines. The hydrogenolysis of this mixture afforded a 70:30 mixture of [methyl-d 3 ] cis- and trans-3'-hydroxycotinine, from which the pure cis-isomer could be isolated by recrystallization from acetone. [Methyl-d 3 ]-trans-3'-hydroxycotinine could be prepared in high yield from the cis-isomer via chiral inversion utilizing a Mitsunobu reaction, or by chromatographic separation from a mixture of the cis- and trans-3'-benzoyloxycotinine, followed by O-debenzoylation in methanolic NaOH. (author)

  19. Teacher's opinions about learning continuum based on the student's level of competence and specific pedagogical materials on anatomical aspects

    Science.gov (United States)

    Astuti, Laili Dwi; Subali, Bambang

    2017-08-01

    This research deals with designing learning continuum for developing a curriculum. The objective of this study is to gather the opinion of public junior and high school teachers about Learning Continuum based on Student's Level of Competence and Specific Pedagogical Material on Anatomical Aspects. This is a survey research. The population of the research is natural science teachers at junior high school and biology teacher at senior high school in Yogyakarta Special Region. Data were collected using a questionnaire. Data were analyzed using a descriptive analysis technique. Based on the results of the survey, the teachers opinion are in accordance with the level of the students they teach. Junior high school teachers argued that anatomical aspects were taught in grade VII,VIII, IX and X on the level of C2 (understanding), the high school teacher argued that anatomical aspects were taught in grade VIII, X and XI on the level of C2 (understanding) and C3 (apply). While according to the opinions of primary school teachers about aspects of anatomy resulted from the research of Subali (2016), anatomy is mostly not taught at the elementary school level, only some of the materials that are taught in this school level. Therefore, the results of the survey can be inferred that the opinions of teachers is still based on the existing curriculum.

  20. Teacher Opinions on the Implementation of Values Education in Teaching Turkish

    Science.gov (United States)

    Kirbas, Abdulkadir

    2017-01-01

    The aim of this study is to determine the realization levels of values education implementations in teaching Turkish by taking the opinions of Turkish teachers. The sample of this study conducted in the survey model comprises 108 Turkish teachers employed at different secondary schools in Erzurum, Bayburt, Gümüshane and Trabzon in the Spring…

  1. TOOL: The Open Opinion Layer

    OpenAIRE

    Masum, Hassan

    2002-01-01

    Shared opinions drive society: what we read, how we vote, and where we shop are all heavily influenced by the choices of others. However, the cost in time and money to systematically share opinions remains high, while the actual performance history of opinion generators is often not tracked. This article explores the development of a distributed open opinion layer, which is given the generic name of TOOL. Similar to the evolution of network protocols as an underlying layer for many comput...

  2. Defining adolescent common mental disorders using electronic primary care data: a comparison with outcomes measured using the CIS-R.

    Science.gov (United States)

    Cornish, Rosie P; John, Ann; Boyd, Andy; Tilling, Kate; Macleod, John

    2016-12-01

    To compare the prevalence of common mental disorders (CMDs) derived from data held in primary care records with that measured using the revised Clinical Interview Schedule (CIS-R) in order to assess the potential robustness of findings based only on routinely collected data. Comparison study using linkage between the Avon Longitudinal Study of Parents and Children (ALSPAC) and electronic primary care records. We studied 1562 adolescents who had completed the CIS-R in ALSPAC at age 17-18 years and had linkage established to their primary care records. Outcome measures from ALSPAC were whether or not an individual met International Classification of Diseases-10 criteria for a diagnosis of (1) a CMD or, specifically, (2) depression. Lists of Read codes corresponding to diagnoses, symptoms and treatments were used to create 12 definitions of CMD and depression alone using the primary care data. We calculated sensitivities and specificities of these, using CIS-R definitions as the reference standard. Sensitivities ranged from 5.2% to 24.3% for depression and from 3.8% to 19.2% for CMD. The specificities of all definitions were above 98% for depression and above 96% for CMD.For both outcomes, the definition that included current diagnosis, treatment or symptoms identified the highest proportion of CIS-R cases. Most individuals meeting case definitions for CMD based on primary care data also met CIS-R case definitions. Conversely many individuals identified as cases using the CIS-R had no evidence of CMD in their clinical records. This suggests that clinical databases are likely to yield underestimates of the burden of CMD in the population. However, clinical records appear to yield valid diagnoses which may be useful for studying risk factors and consequences of CMD. The greatest epidemiological value may be obtained when information is available from survey and clinical records. Published by the BMJ Publishing Group Limited. For permission to use (where not already

  3. Questions on maintenance of ecological safety in space of the CIS

    International Nuclear Information System (INIS)

    Maharramov, A.A.

    2009-01-01

    Disintegration of the USSR has led to disintegration uniform economic and legal space and it has led to occurrence of some problems in ecological sphere. In given article it is shown some directions of maintenance of ecological safety, agreements on this sphere and organizational mechanisms, forms of mutual relations of the CIS countries in this sphere. At the end it is shownthe basic directions on maintenance of ecological safety in framework of CIS and elements of development of mutual relations of the CIS countries

  4. The IRSN 2008 barometer. The opinion on risks and security of the French population. Global results

    International Nuclear Information System (INIS)

    2008-01-01

    This report presents and comments the results of a survey during which a sample of the French population has been questioned on their current concerns (about the society, about the environment, about quantitative criteria of risk management and about the image of science), on their opinion of scientific expertise (who should control a risky installation, the role and image of experts, the access to expertise files, the perception of pluralist structures), the opinion on 31 risk situations (risks to which French people feel exposed, confidence in authorities, truth of information on hazards, hierarchy of the 31 situations), the opinion on the nuclear activity and industry (the nuclear risk, the credibility and expertise of interveners), incidents which occurred in 2007, the demand of information on the nuclear risk), and on their opinion about radiotherapy accidents in France

  5. Public opinion on age-related degradation in nuclear power plants

    International Nuclear Information System (INIS)

    Matsuda, Toshihiro

    2005-01-01

    The first objective of this study is to shed light on the public opinion on age-related degradation at nuclear power plants, namely, on how the general public recognizes or views age-related degradation, which is a safety-related issue and one of the factors contributing to accidents and failures which occur at nuclear power plants. The second objective is to look into the impacts of the accident at Mihama Unit 3, which was caused by a failure to check on the piping wall thickness, on the public opinion on age-related degradation. The first survey was conducted in August 2003, followed by the second survey in October 2004, two months after the accident. The surveys found that the age-related degradation is being perceived by people as one of the risk factors that affect the safety of nuclear power plants. The characteristics of the citizens' perceptions toward age-related degradation in the form of piping cracks are that: (a) many respondents feel uneasy but a relatively few people consider that nuclear operators are technologically capable of coping with this problem; (b) many people believe that radioactivity may be released; and (c) numerous respondents consider that signs of cracks must be thoroughly detected through inspections, while on the other hand, a large percentage of the respondents attribute the accident to improper inspections/maintenance. Based on these results, the government and nuclear operators are expected to give most illuminating explanation on the current situation of and remedial measures against age-related degradation at nuclear power plants. As for the effects of the Mihama-3 accident on the public opinion on age-related degradation, it was revealed that the accident has not so significantly affected the general view for the safety of nuclear power plants, but has newly or strongly aroused people's consciousness of two of the risk factors - improper inspections/maintenance and the age-related degradation of piping. (author)

  6. Thermodynamic state ensemble models of cis-regulation.

    Directory of Open Access Journals (Sweden)

    Marc S Sherman

    Full Text Available A major goal in computational biology is to develop models that accurately predict a gene's expression from its surrounding regulatory DNA. Here we present one class of such models, thermodynamic state ensemble models. We describe the biochemical derivation of the thermodynamic framework in simple terms, and lay out the mathematical components that comprise each model. These components include (1 the possible states of a promoter, where a state is defined as a particular arrangement of transcription factors bound to a DNA promoter, (2 the binding constants that describe the affinity of the protein-protein and protein-DNA interactions that occur in each state, and (3 whether each state is capable of transcribing. Using these components, we demonstrate how to compute a cis-regulatory function that encodes the probability of a promoter being active. Our intention is to provide enough detail so that readers with little background in thermodynamics can compose their own cis-regulatory functions. To facilitate this goal, we also describe a matrix form of the model that can be easily coded in any programming language. This formalism has great flexibility, which we show by illustrating how phenomena such as competition between transcription factors and cooperativity are readily incorporated into these models. Using this framework, we also demonstrate that Michaelis-like functions, another class of cis-regulatory models, are a subset of the thermodynamic framework with specific assumptions. By recasting Michaelis-like functions as thermodynamic functions, we emphasize the relationship between these models and delineate the specific circumstances representable by each approach. Application of thermodynamic state ensemble models is likely to be an important tool in unraveling the physical basis of combinatorial cis-regulation and in generating formalisms that accurately predict gene expression from DNA sequence.

  7. Action of cis-dichlorobis (cyclopentylamine) platinum (2) (cis-PAD) on L5178Y cells of two strains inversely cross-sensitive to X-rays and UV-light. Part 3. Differential effects of caffeine

    International Nuclear Information System (INIS)

    Szumiel, I.

    1977-01-01

    Two strains of L5178Y murine lymphoma, inversely cross-sensitive to X-rays and UV-light, were shown previously to respond to treatment with an antitumour platinum complex, cis-PAD, in a similar manner as to UV. The difference in sensitivity to cis-PAD, found in L5178Y-R and L5178Y-S cells is not caused by a difference in ability to bind platinum complex. Enhancement of chromosomal damage and potentiation of lethal effect of cis-PAD by 0.75 mM caffeine were found in cis-PAD and UV-light-resistant L5178Y-S strain but not in cis-PAD and UV-light-sensitive L5178Y-R strain. These results suggest that the extreme sensitivity of L5178Y-R strain to cis-PAD and UV-light is caused to some extent by deficiency in a caffeine-sensitive post-replication repair system. (author)

  8. Action of cis-dichlorobis (cyclopentylamine) platinum (2) (cis-PAD) on L5178Y cells of two strains inversely cross-sensitive to X-rays and UV-light. Part 1. Cytotoxicity

    International Nuclear Information System (INIS)

    Szumiel, I.

    1977-01-01

    The response to cis-PAD, an antitumour platinum complex, was studied in two strains of murine lymphoma L5178Y cross-sensitive to X-rays and UV light. Dose-survival relationship, DNA synthesis, formation of chromatid aberrations, progression through the cell cycle, and growth and viability changes after 1 h cis-PAD treatment at 37 0 C were examined and compared with respective effects of X-rays and UV-light. In both strains studied, cis-PAD causes immediate inhibition of progression through the cell cycle, reduced rate of DNA synthesis, delayed appearance of chromatid aberrations and delayed death. However, there is a marked difference in sensitivity to cis-PAD between L5178Y-S strain (D 0 ca.5.8 μg/ml) and L5178Y-R strain (D 0 ca. 2.5μg/ml). In both strains a close resemblance was found between dose-survival relationship after cis-PAD and UV-light treatment, respectively. (author)

  9. Barcoded DNA-tag reporters for multiplex cis-regulatory analysis.

    Directory of Open Access Journals (Sweden)

    Jongmin Nam

    Full Text Available Cis-regulatory DNA sequences causally mediate patterns of gene expression, but efficient experimental analysis of these control systems has remained challenging. Here we develop a new version of "barcoded" DNA-tag reporters, "Nanotags" that permit simultaneous quantitative analysis of up to 130 distinct cis-regulatory modules (CRMs. The activities of these reporters are measured in single experiments by the NanoString RNA counting method and other quantitative procedures. We demonstrate the efficiency of the Nanotag method by simultaneously measuring hourly temporal activities of 126 CRMs from 46 genes in the developing sea urchin embryo, otherwise a virtually impossible task. Nanotags are also used in gene perturbation experiments to reveal cis-regulatory responses of many CRMs at once. Nanotag methodology can be applied to many research areas, ranging from gene regulatory networks to functional and evolutionary genomics.

  10. Opinion competition dynamics on multiplex networks

    Science.gov (United States)

    Amato, R.; Kouvaris, N. E.; San Miguel, M.; Díaz-Guilera, A.

    2017-12-01

    Multilayer and multiplex networks represent a good proxy for the description of social phenomena where social structure is important and can have different origins. Here, we propose a model of opinion competition where individuals are organized according to two different structures in two layers. Agents exchange opinions according to the Abrams-Strogatz model in each layer separately and opinions can be copied across layers by the same individual. In each layer a different opinion is dominant, so each layer has a different absorbing state. Consensus in one opinion is not the only possible stable solution because of the interaction between the two layers. A new mean field solution has been found where both opinions coexist. In a finite system there is a long transient time for the dynamical coexistence of both opinions. However, the system ends in a consensus state due to finite size effects. We analyze sparse topologies in the two layers and the existence of positive correlations between them, which enables the coexistence of inter-layer groups of agents sharing the same opinion.

  11. Competing opinion diffusion on social networks.

    Science.gov (United States)

    Hu, Haibo

    2017-11-01

    Opinion competition is a common phenomenon in real life, such as with opinions on controversial issues or political candidates; however, modelling this competition remains largely unexplored. To bridge this gap, we propose a model of competing opinion diffusion on social networks taking into account degree-dependent fitness or persuasiveness. We study the combined influence of social networks, individual fitnesses and attributes, as well as mass media on people's opinions, and find that both social networks and mass media act as amplifiers in opinion diffusion, the amplifying effect of which can be quantitatively characterized. We analytically obtain the probability that each opinion will ultimately pervade the whole society when there are no committed people in networks, and the final proportion of each opinion at the steady state when there are committed people in networks. The results of numerical simulations show good agreement with those obtained through an analytical approach. This study provides insight into the collective influence of individual attributes, local social networks and global media on opinion diffusion, and contributes to a comprehensive understanding of competing diffusion behaviours in the real world.

  12. Public opinion on abortion in Mexico City after the landmark reform.

    Science.gov (United States)

    Wilson, Kate S; García, Sandra G; Díaz Olavarrieta, Claudia; Villalobos-Hernández, Aremis; Rodríguez, Jorge Valencia; Smith, Patricio Sanhueza; Burks, Courtney

    2011-09-01

    This article presents findings from three opinion surveys conducted among representative samples of Mexico City residents: the first one immediately prior to the groundbreaking legalization of first-trimester abortion in April 2007, and one and two years after the reform. Bivariate and multivariate analyses were performed to assess changes in opinion concerning abortion and correlates of favorable opinion following reform. In 2009 a clear majority (74 percent) of respondents were in support of the Mexico City law allowing for elective first-trimester abortion, compared with 63 percent in 2008 and 38 percent in 2007. A significant increase in support for extending the law to the rest of Mexico was found: from 51 percent in 2007 to 70 percent in 2008 and 83 percent in 2009. In 2008 the significant independent correlates of support for the Mexico City law were education, infrequent religious service attendance, sex (being male), and political party affiliation; in 2009 they were education beyond high school, infrequent religious service attendance, and ever having been married.

  13. Non-consensus Opinion Models on Complex Networks

    Science.gov (United States)

    Li, Qian; Braunstein, Lidia A.; Wang, Huijuan; Shao, Jia; Stanley, H. Eugene; Havlin, Shlomo

    2013-04-01

    Social dynamic opinion models have been widely studied to understand how interactions among individuals cause opinions to evolve. Most opinion models that utilize spin interaction models usually produce a consensus steady state in which only one opinion exists. Because in reality different opinions usually coexist, we focus on non-consensus opinion models in which above a certain threshold two opinions coexist in a stable relationship. We revisit and extend the non-consensus opinion (NCO) model introduced by Shao et al. (Phys. Rev. Lett. 103:01870, 2009). The NCO model in random networks displays a second order phase transition that belongs to regular mean field percolation and is characterized by the appearance (above a certain threshold) of a large spanning cluster of the minority opinion. We generalize the NCO model by adding a weight factor W to each individual's original opinion when determining their future opinion (NCO W model). We find that as W increases the minority opinion holders tend to form stable clusters with a smaller initial minority fraction than in the NCO model. We also revisit another non-consensus opinion model based on the NCO model, the inflexible contrarian opinion (ICO) model (Li et al. in Phys. Rev. E 84:066101, 2011), which introduces inflexible contrarians to model the competition between two opinions in a steady state. Inflexible contrarians are individuals that never change their original opinion but may influence the opinions of others. To place the inflexible contrarians in the ICO model we use two different strategies, random placement and one in which high-degree nodes are targeted. The inflexible contrarians effectively decrease the size of the largest rival-opinion cluster in both strategies, but the effect is more pronounced under the targeted method. All of the above models have previously been explored in terms of a single network, but human communities are usually interconnected, not isolated. Because opinions propagate not

  14. Geographic variation in opinions on climate change at state and local scales in the USA

    Science.gov (United States)

    Howe, Peter D.; Mildenberger, Matto; Marlon, Jennifer R.; Leiserowitz, Anthony

    2015-06-01

    Addressing climate change in the United States requires enactment of national, state and local mitigation and adaptation policies. The success of these initiatives depends on public opinion, policy support and behaviours at appropriate scales. Public opinion, however, is typically measured with national surveys that obscure geographic variability across regions, states and localities. Here we present independently validated high-resolution opinion estimates using a multilevel regression and poststratification model. The model accurately predicts climate change beliefs, risk perceptions and policy preferences at the state, congressional district, metropolitan and county levels, using a concise set of demographic and geographic predictors. The analysis finds substantial variation in public opinion across the nation. Nationally, 63% of Americans believe global warming is happening, but county-level estimates range from 43 to 80%, leading to a diversity of political environments for climate policy. These estimates provide an important new source of information for policymakers, educators and scientists to more effectively address the challenges of climate change.

  15. Development of cooperation of the CIS member states in the peaceful use of atomic energy

    International Nuclear Information System (INIS)

    Sobolev, A.Ye.

    2012-01-01

    Full text: Cooperation platform: Attraction of potential investors; Promotion of national goods and services; Pursuit of national and commercial interests. The Commission of the CIS Member States for the Peaceful Use of Atomic Energy is a nuclear cooperation body and the CIS intergovernmental coordinating and advisory authority. The Commission of the CIS Member States for the Peaceful Use of Atomic Energy coordinates and expands the spheres of cooperation. Members of the Commission- state-appointed heads of the authorized CIS member state bodies in the peaceful use of atomic energy; Secretariat is the working body of the Commission. Expert work groups formed within the CIS members States Commission: On the status of the draft Agreement on Coordination of Interstate Relations in the Peaceful Use of Atomic Energy in the CIS Territory; On the establishment of the CIS regional center for advanced training of medical physicists; Formation of an integrated system for the maintenance of safety of the nuclear research facilities. Issues of establishing the Coalition of the CIS Nuclear Research reactors; Formation of mechanisms for the convergence of the CIS member states legal and technical regulations in the peaceful use of atomic energy; Adaptation and introduction in the CIS members states of international standards in the field of using industrial radiation technologies and ensuring radiation safety; Basic forms of the CIS cooperation in ensuring economic security of projects for the peaceful use of atomic energy; Establishment of a system for the management of intellectual assets of the CIS members states; On the use of tele medical technologies of Ros atom State Cooperation- FMBA-MEPHI in diagnosis of oncologic diseases; Development of the major components of the Concept of Ensuring Nuclear, radiation and Radio ecological; Policy of the CIS Member States in the Peaceful Use of Atomic Energy; Joint implementation of the project to establish and implement a program of

  16. Ultraviolet irradiation produces cytotoxic synergy and increased DNA interstrand crosslinking with cis- and trans-diamminedichloroplatinum(II)

    International Nuclear Information System (INIS)

    Swinnen, L.J.; Erickson, L.C.

    1989-01-01

    The excision-repair mechanism responsible for the removal of UV-induced thymine dimers may also play a role in the repair of cis-diamminedichloroplatinum(II) (cis-DDP)-induced DNA adducts in both bacteria and mammalian cells. It was hypothesized that UV dimers and cis-DDP adducts, when present simultaneously, might compete for a common repair system. Colony survival assays were performed in HT-29 human colon carcinoma cells exposed either to cis-DDP alone or to cis-DDP immediately followed by UV exposure. Progressively greater cytotoxic synergy with both increasing UV dose and cis-DDP dose was observed, to a point of saturation beyond which further toxicity was purely additive. An approximate doubling in DNA crosslink frequency, relative to cis-DDP alone, was found in cells exposed to cis-DDP plus UV. Since cis-DDP produces both inter- and intrastrand DNA crosslinks similar studies were performed with trans-DDP, which is incapable of producing intrastrand crosslinks, but does produce interstrand crosslinks. Cytotoxic synergy and increased interstrand crosslinking again resulted from the addition of UV exposure, but not to the same extent as seen with cis-DDP. (author)

  17. Factors affecting the opinions of family physicians regarding generic drugs – a questionnaire based study

    Directory of Open Access Journals (Sweden)

    Pawel Lewek

    2014-12-01

    Full Text Available A range of factors are believed to exert a negative influence on opinions of physicians about generic drugs.The aim of this study was to survey the opinions of primary care doctors on generics, and determine the factors which may affect them. A questionnaire comprising thirty eight questions was distributed among primary care doctors working in seventy out-patient clinics of the Lodzkie province, Poland, during the period of January 1, 2010 – December 31, 2010. A total of170 of 183 participants completed the survey (average age 48.5; 70.0% women: a 92.9%response rate. While 38.8% of physicians claimed that generics were worse than brand name drugs, 54.1% considered them to be better. However, 36.5% of the doctors did not choose generics for their own use. Two key opinions were identified among the responses concerning the effectiveness of generic drugs: use of generic drugs by the physician (p<0.001, and their opinion that pharmacists do inform patients about generic drugs (p<0.05. Although existing evidence confirms that generic and brand name drugs are equally effective, many physicians doubt this, which prevents them from being used as cost effective drug therapy. In order to increase healthcare savings through the use of generics, these factors should be addressed: for example, convincing a physician to adopt generics for personal use may be an efficient way to support more cost effective treatment of his patients.

  18. [Oral contraception in France in 2001: results of an opinion poll survey conducted on 3609 women between 15 and 45].

    Science.gov (United States)

    Laveissière, M N; Pélissier, C; Lê, M G

    2003-03-01

    The aim of this study concerning the taking of the pill in France in 2001 was threefold, i.e. to assess its rate as well as its characteristics of use, and to appraise the most frequent side effects as reported by women. Three thousand six hundred and nine women representative of the French female population between 15 and 45 years of age were recruited thanks to a survey, which took place in 2001. The data were collected from self-questionnaires. Women on the whole have quite a good opinion of oral contraception and most of them are convinced of its efficiency. As far as pill tolerance is concerned, opinions do vary, more than half of the women judging that being on the pill is not without side-effects. Though, the rate of use of oral contraceptives has increased by 12% since 1994. Most women (48%) use first and second generation pills and this in all age brackets. Thirty per cent of women aged 30 to 45 keep loyal to the same patent medicine, which they keep using for more than 10 years. Among the side-effects that can be found, two of them--putting on weight (31%) and hydrosodium retention (26%)--are the most frequently quoted, in all age brackets. This accounts for the relatively low ratio of women who find their pill quite satisfactory (58% of the cases). Despite the diversity of all the different patented pills that are available, efforts are still to be made in order to reduce what side-effects are encountered when using them.

  19. Opinions of Female Juvenile Delinquents about Their Interactions in Chat Rooms

    Science.gov (United States)

    Sanger, Dixie; Long, Amie; Ritzman, Mitzi; Stofer, Keri; Davis, Candy

    2004-01-01

    The purpose of this study was to survey the opinions of 62 adolescent females residing in a correctional facility about their use of the Internet to participate in chat room conversations. Findings indicated that 54 of 62 girls (87.09%), with a mean age of 16.72 years, participated in chat room interactions. Most (n = 47) interacted in chat rooms…

  20. Fashion clothing involvement, opinion leadership and opinion seeking amongst black generation Y students / Pulaki Joseph Tshabalala

    OpenAIRE

    Tshabalala, Pulaki Joseph

    2014-01-01

    Opinion leadership and opinion seeking are central constructs in academic studies of new product innovations. Fashion opinion leaders as those individuals who accelerate the fashion maturity process by legitimising a fashionable trend and influence other consumers to adopt the new innovative style as a replacement for the current accepted one. Consumers who accept information and adopt new style innovations are called opinion seekers and are important to the diffusion of new fashions because ...

  1. Whole-body kinetics and dosimetry of cis-4-[18F]fluoro-l-proline

    International Nuclear Information System (INIS)

    Boerner, Anne R.; Langen, Karl-J.; Herzog, Hans; Hamacher, Kurt; Mueller-Mattheis, Volker; Schmitz, Thomas; Ackermann, Rolf; Coenen, Heinz H.

    2001-01-01

    The whole-body distribution of 4-cis[ 18 F]fluoro-L-proline (cis-FPro) was studied in six patients with urological tumors by PET. Based on the IMEDOSE and MIRDOSE procedures radiation absorbed doses were estimated from whole-body PET scans acquired at 1 and 3-5 h after i.v. injection of 400 MBq cis-FPro. Cis-FPro showed high retention in the renal cortex and a slight uptake in liver and pancreas. Urinary excretion ranged from 12 to 19% at 5 h p.i. Highest absorbed doses were found for the urinary bladder wall and the kidneys (44.1/44.0 μGy/MBq). The effective dose according to ICRP 60 was 15.1 μSv/MBq for adults. This leads to an effective dose of 6.0 mSv in a PET study using 400 MBq cis-FPro

  2. Whole-body kinetics and dosimetry of cis-4-[(18)F]fluoro-L-proline.

    Science.gov (United States)

    Börner, A R; Langen, K J; Herzog, H; Hamacher, K; Müller-Mattheis, V; Schmitz, T; Ackermann, R; Coenen, H H

    2001-04-01

    The whole-body distribution of 4-cis[(18)F]fluoro-L-proline (cis-FPro) was studied in six patients with urological tumors by PET. Based on the IMEDOSE and MIRDOSE procedures radiation absorbed doses were estimated from whole-body PET scans acquired at 1 and 3-5 h after i.v. injection of 400 MBq cis-FPro. Cis-FPro showed high retention in the renal cortex and a slight uptake in liver and pancreas. Urinary excretion ranged from 12 to 19% at 5 h p.i. Highest absorbed doses were found for the urinary bladder wall and the kidneys (44.1/44.0 microGy/mbq). The effective dose according to ICRP 60 was 15.1 microSv/mbq for adults. This leads to an effective dose of 6.0 mSv in a PET study using 400 MBq cis-FPro.

  3. Conjugated linoleic acid (CLA. Cis 9, trans 11 and trans 10, cis 12 isomer detection in crude and refined corn oils by capillary GC

    Directory of Open Access Journals (Sweden)

    Özlem Tokuşoğlu

    2008-06-01

    Full Text Available Conjugated linoleic acids (CLAs exhibit protective effects against various types of cancer and heart diseases. With the newly developed capillary gas chromatographic method (GC, cis9, trans11 and trans10, cis12 octadecadienoic acid isomers of CLA (C18:2 were determined in crude and refined corn oils as qualitative and quantitative measurements. Cis 9, trans11 C18:2 (c9, t11 CLA was the major CLA isomer in both oils. It was found that c9, t11 CLA was 0.62% of the total lipid in crude oil and 1.24% of the total lipid in refined oil. Using the refining process, the total CLA was 1.38% whereas that of crude corn oil was 0.62%. An approximate 2.2 fold increase in the total CLA was found in refined oil (n = 9 (p y = 2.782x + 0.046 (R2 = 0.9999] were performed (p El ácido linoleico conjugado (CLA parece exhibir efecto protector frente a enfermedades cardiovasculares y varios tipos de cáncer. En este trabajo, se establece un mátodo analítico mediante cromatografía de gases con columna capilar para la determinación cualitativa y cuantitativa de los isómeros cis 9,trans 11 y trans 10, cis 12 en aceites de maiz crudo y refinado. El isómero cis 9, trans11 C18:2 fue el mayoritario encontrándose en concentraciones de 0.62% en el aceite cru,do y de 1.24 % en el aceite refinado. La cantidad total de CLA encontrada en el aceite refinado (n = 9 (p 2 = 0.9999 y de recuperación [y = 2.782x+0.046 (R2 = 0.9999]. El método cromatográfico propuesto podría ser usado para el control de calidad de los aceites vegetales.

  4. A national survey of program director opinions of core competencies and structure of hand surgery fellowship training.

    Science.gov (United States)

    Sears, Erika Davis; Larson, Bradley P; Chung, Kevin C

    2012-10-01

    We assessed hand surgery program directors' opinions of essential components of hand surgery training and potential changes in the structure of hand surgery programs. We recruited all 74 program directors of Accreditation Council of Graduate Medical Education-accredited hand surgery fellowship programs to participate. We designed a web-based survey to assess program directors' support for changes in the structure of training programs and to assess opinions of components that are essential for graduates to be proficient. Respondents were asked to rate 9 general areas of practice, 97 knowledge topics, and 172 procedures. Each component was considered essential if 50% or more of respondents thought that graduates must be fully knowledgeable of the topic and be able to perform the procedure at the end of training. The response rate was 84% (n = 62). A minority of program directors (n = 15; 24%) supported creation of additional pathways for hand surgery training, and nearly three-quarters (n = 46; 74%) preferred a fellowship model to an integrated residency model. Most program directors (n = 40; 65%) thought that a 1-year fellowship was sufficient to train a competent hand surgeon. Wrist, distal radius/ulna, forearm, and peripheral nerve conditions were rated as essential areas of practice. Of the detailed components, 76 of 97 knowledge topics and 98 of 172 procedures were rated as essential. Only 48% respondents (n = 30) rated microsurgery as it relates to free tissue transfer as essential. However, small and large vessel laceration repairs were rated as essential by 92% (n = 57) and 77% (n = 48) of respondents, respectively. This study found resistance to prolonging the length of fellowship training and introduction of an integrated residency pathway. To train all hand surgeons in essential components of hand surgery, programs must individually evaluate exposure provided and find innovative ways to augment training when necessary. Studies of curriculum content in hand

  5. Evolution of Enzymatic Activities in the Enolase Superfamily: Stereochemically Distinct Mechanisms in Two Families of cis,cis-Muconate Lactonizing Enzymes

    Energy Technology Data Exchange (ETDEWEB)

    Sakai, A.; Fedorov, A; Fedorov, E; Schnoes, A; Glasner, M; Burley, S; Babbitt, P; Almo, S; Gerlt, J

    2009-01-01

    The mechanistically diverse enolase superfamily is a paradigm for elucidating Nature's strategies for divergent evolution of enzyme function. Each of the different reactions catalyzed by members of the superfamily is initiated by abstraction of the a-proton of a carboxylate substrate that is coordinated to an essential Mg2+. The muconate lactonizing enzyme (MLE) from Pseudomonas putida, a member of a family that catalyzes the syn-cycloisomerization of cis,cis-muconate to (4S)-muconolactone in the e-ketoadipate pathway, has provided critical insights into the structural bases for evolution of function within the superfamily. A second, divergent family of homologous MLEs that catalyzes anti-cycloisomerization has been identified. Structures of members of both families liganded with the common (4S)-muconolactone product (syn, Pseudomonas fluorescens, gi 70731221; anti, Mycobacterium smegmatis, gi 118470554) document that the conserved Lys at the end of the second e-strand in the (e/a)7e-barrel domain serves as the acid catalyst in both reactions. The different stereochemical courses (syn and anti) result from different structural strategies for determining substrate specificity: although the distal carboxylate group of the cis,cis-muconate substrate attacks the same face of the proximal double bond, opposite faces of the resulting enolate anion intermediate are presented to the conserved Lys acid catalyst. The discovery of two families of homologous, but stereochemically distinct, MLEs likely provides an example of 'pseudoconvergent' evolution of the same function from different homologous progenitors within the enolase superfamily, in which different spatial arrangements of active site functional groups and substrate specificity determinants support catalysis of the same reaction.

  6. Evolution of Enzymatic Activities in the Enolase Superfamily: Stereochemically Distinct Mechanisms in Two Families of cis,cis-Muconate Lactonizing Enzymes†

    Science.gov (United States)

    Sakai, Ayano; Fedorov, Alexander A.; Fedorov, Elena V.; Schnoes, Alexandra M.; Glasner, Margaret E.; Brown, Shoshana; Rutter, Marc E.; Bain, Kevin; Chang, Shawn; Gheyi, Tarun; Sauder, J. Michael; Burley, Stephen K.; Babbitt, Patricia C.; Almo, Steven C.; Gerlt, John A.

    2009-01-01

    The mechanistically diverse enolase superfamily is a paradigm for elucidating Nature’s strategies for divergent evolution of enzyme function. Each of the different reactions catalyzed by members of the superfamily is initiated by abstraction of the α-proton of a carboxylate substrate that is coordinated to an essential Mg2+. The muconate lactonizing enzyme (MLE) from Pseudomonas putida, a member of a family that catalyzes the syn-cycloisomerization of cis,cis-muconate to (4S)-muconolactone in the β-ketoadipate pathway, has provided critical insights into the structural bases for evolution of function within the superfamily. A second, divergent family of homologues MLEs that catalyzes anti-cycloisomerization has been identified. Structures of members of both families liganded with the common (4S)-muconolactone product (syn, Pseudomonas fluorescens, GI:70731221; anti, Mycobacterium smegmatis, GI:118470554) document that the conserved Lys at the end of the second β-strand in the (β/α)7β-barrel domain serves as the acid catalyst in both reactions. The different stereochemical courses (syn and anti) result from different structural strategies for determining substrate specificity: although the distal carboxylate group of the cis,cis-muconate substrate attacks the same face of the proximal double bond, opposite faces of the resulting enolate anion intermediate are presented to the conserved Lys acid catalyst. The discovery of two families of homologous, but stereochemically distinct, MLEs likely provides an example of “pseudoconvergent” evolution of the same function from different homologous progenitors within the enolase superfamily, in which different spatial arrangements of active site functional groups and substrate specificity determinants support catalysis of the same reaction. PMID:19220063

  7. The value of bladder mapping and prostatic urethra biopsies for detection of carcinoma in situ (CIS).

    Science.gov (United States)

    Gudjónsson, Sigurdur; Bläckberg, Mats; Chebil, Gunilla; Jahnson, Staffan; Olsson, Hans; Bendahl, Pär-Ola; Månsson, Wiking; Liedberg, Fredrik

    2012-07-01

    It is well known that CIS is a major risk factor for muscle-invasive bladder cancer and that this entity can be difficult to diagnose. Taking cold-cup mapping biopsies from different areas of the bladder (BMAP) is commonly used in patients at risk of harbouring CIS. The diagnostic accuracy of this approach has not been assessed until now. By using the CIS found in the cystoprostatectomy specimen as an indicator of the true occurrence of CIS and comparing that with the findings of BMAP, it is clear that the sensitivity of BMAP to detect CIS when present is low and that negative findings should be considered unreliable. To assess the value of bladder mapping and prostatic urethra biopsies for detection of urothelial carcinoma in situ (CIS). CIS of the urinary bladder is a flat high-grade lesion of the mucosa associated with a significant risk of progression to muscle-invasive disease. CIS is difficult to identify on cystoscopy, and definite diagnosis requires histopathology. Traditionally, if CIS is suspected, multiple cold-cup biopsies are taken from the bladder mucosa, and resection biopsies are obtained from the prostatic urethra in males. This approach is often called bladder mapping (BMAP). The accuracy of BMAP as a diagnostic tool is not known. Male patients with bladder cancer scheduled for cystectomy underwent cold-cup bladder biopsies (sidewalls, posterior wall, dome, trigone), and resection biopsies were taken from the prostatic urethra. After cystectomy, the surgical specimen was investigated in a standardised manner and subsequently compared with the BMAP biopsies for the presence of CIS. The histopathology reports of 162 patients were analysed. CIS was detected in 46% of the cystoprostatectomy specimens, and multiple (≥2) CIS lesions were found in 30%. BMAP (cold-cup bladder biopsies + resection biopsies from the prostatic urethra) provided sensitivity of 51% for any CIS, and 55% for multiple CIS lesions. The cold-cup biopsies for CIS in the bladder

  8. Functioning of primary health care in opinion of managers of primary health care units.

    Science.gov (United States)

    Bojar, I; Wdowiak, L; Kwiatosz-Muc, M

    2006-01-01

    The aim of the research is to get to know opinions of primary health care managers concerning working of primary health care and concerning quality of medical services offered by family doctors out-patient clinics. The research among managers of primary health care units took place in all out-patient clinics in Lublin province. Research instrument was survey questionnaire of authors own construction. Results were statistically analyzed. From 460 surveys sent, 108 questionnaires were accepted to analysis. Majority of managers of out-patient clinics of primary health care is satisfied with the way and the quality of work of employed staff. In opinion of 71.3% of managers access to family doctor services is very good. Availability of primary health care services is better estimated by managers of not public units. The occupied local provide comfortable work for the staff in opinion of 78.5% of surveyed managers of out-patient clinics. Managers estimate the level of their services as very good (37.96%) and good (37.96%) comparing to other such a subjects present in the market. Internal program of improving quality is run in 22% of out-patient clinics, which were investigated. Managers of primary health care units assess the quality of their services as good and very good. They estimate positively the comfort and politeness in serving patients as well as technical status of equipment and the lodging. They assess availability of their services as very good. Large group of managers of family doctors practices recognizes neighborhood practices as a competitors.

  9. Columbia River Coordinated Information System (CIS), 1992-1993 Annual Report.

    Energy Technology Data Exchange (ETDEWEB)

    Rowe, Mike; Roger, Phillip B.; O' Connor, Dick

    1993-11-01

    The purposes of this report are to: (1) describe the project to date; (2) to document the work and accomplishments of the (CIS) project for Fiscal Year 1993; and (3) to provide a glimpse of future project direction. The concept of a Coordinated Information System (CIS) as an approach to meeting the growing needs for regionally standardized anadromous fish information.

  10. Hybrid macrocycle formation and spiro annulation on cis-syn-cis-tricyclo[6.3.0.02,6]undeca-3,11-dione and its congeners via ring-closing metathesis

    Directory of Open Access Journals (Sweden)

    Sambasivarao Kotha

    2015-07-01

    Full Text Available We have developed a simple methodology to transform cis-syn-cis-triquinane derivative 2 into the diindole based macrocycle 6 involving Fischer indolization and ring-closing metathesis (RCM. Various spiro-polyquinane derivatives have been assembled via RCM as a key step.

  11. Plutonium - the ultrapoison? An expert's opinion about an expert opinion

    International Nuclear Information System (INIS)

    Stoll, W.; Becker, K.

    1989-01-01

    In an expert opinion written by Professor H. Kuni, Marburg, for the North Rhine-Westphalian state government, plutonium is called by far the most dangerous element in the Periodic Table. The Marburg medical expert holds that even improved legal instruments are unable to warrant effective protection of the workers handling this material, in the light of the present standards of industrial safety, because of radiological conditions and measuring problems with plutonium isotopes. In this article by an internationally renowned expert in the field, the ideas expressed in the expert opinion about the toxicity of plutonium, the cause-and-effect relationship in radiation damage by plutonium, and recent findings about the toxicity are subjected to a critical review. On the basis of results of radiation protection and of case studies, the statements in the expert opinion are contrasted with facts which make them appear in a very different light. (orig./RB) [de

  12. Crystal structure of cis-anti-cis-dicyclohexane-18-crown-6 acetonitrile disolvate

    Directory of Open Access Journals (Sweden)

    Alexander Nazarenko

    2015-07-01

    Full Text Available The title compound (systematic name: cis-anti-cis-2,5,8,15,18,21-hexaoxatricyclo[20.4.0.09,14]hexacosane acetonitrile disolvate, C20H36O6·2CH3CN, crystallizes from an acetonitrile solution of dicyclohexane-18-crown-6 on evaporation. The molecule is arranged around a center of symmetry with half the crown ether molecule and one molecule of acetonitrile symmetry independent. All O—C—C—O torsion angles are gauche while all C—O—C—C angles are trans. The sequence of torsion angles is [(tg+t(tg−t]3; the geometry of oxygen atoms is close to pseudo-D3d with three atoms below and three atoms above the mean plane, with an average deviation of ±0.16 (1 Å from the mean plane. This geometry is identical to that observed in metal ion complexes of dicyclohexane-18-crown-6 but differs significantly from the conformation of a free unsolvated molecule. Each acetonitrile molecule connects to a crown ether molecule via two of its methyl group H atoms (C—H...O. Weaker interactions exist between the third H atom of the acetonitrile methyl group and an O atom of a neighbouring crown ether molecule (C—H...O; and between the N atom of the acetonitrile molecule and a H atom of another neighbouring crown ether molecule. All these intermolecular interactions create a three-dimensional network stabilizing the disolvate.

  13. Students Opinions and Attitudes towards Physical Education Classes in Kuwait Public Schools

    Science.gov (United States)

    Mohammed, Heyam Reda; Mohammad, Mona Ahmad

    2012-01-01

    The aim of study was to investigate student opinion and attitude toward physical education classes. Two thousand seven hundred (2700) students answered the survey: 1239 (45.3%) were male students and 1497 (54.7%) were female from Kuwait six districts: Al_Hawalli, Al_Asimah, Al_Jahra, Al_Mobarak, Al_Farwniah, Al_Ahmadi. Weight Status was determined…

  14. I Don't Know. The Effect of Question Polarity on No-opinion Answers

    NARCIS (Netherlands)

    Kamoen, N.; van de Pol, Jasper; Krouwel, A.P.M.; de Vreese, Claes; Holleman, Bregje

    2018-01-01

    A new type of political attitude survey that has gained popularity in Europe and in the United States is the voting advice application (VAA). VAAs provide users with a voting advice based on their answers to a set of attitude questions. In the calculation of this advice, no-opinion answers are

  15. Nuclear energy and public opinion: arousal of a myth

    International Nuclear Information System (INIS)

    Agrafiotis, D.; Delarminat, E.; Morlat, G.; Pages, J.P.

    1977-01-01

    In order to explain why an individual or the public opinion is in favour or against the peaceful uses of nuclear energy, one should not only consider the dimension of the involved risk, as radiation protection and safety experts will often do. Many other dimensions should be considered all the more as the nuclear problem is gaining importance on a national level, becoming the topic of the day in press and other media and the subject of 'definite' position from political parties and social groups. An investigation carried out within the Protection Division of the French Atomic Energy Commission (C.E.A.) has made it possible to specify the socio-cultural dimensions at the origin of the attitudes taken on the nuclear problem in France. The nuclear topic was therefore compared with other present topics interesting public opinion; this comparison was made possible by means of an attitude survey covering various social groups. A model of social perception was thus developed [fr

  16. The IRSN 2010 barometer. The opinion on risks and security of the French population. Global results

    International Nuclear Information System (INIS)

    2010-01-01

    This report presents and comments the results of a survey during which a sample of the French population has been questioned on their current concerns (about the society, about the environment, about the image of science), on their opinion on scientific expertise (who should control a risky installation, the role and image of experts, the access to expertise files, the perception of pluralist structures), the opinion on 32 risk situations (risks to which French people feel exposed, confidence in authorities, truth of information on hazards, hierarchy of the 32 situations), the opinion on the nuclear activity and industry (the nuclear risk, the credibility and expertise of interveners, incidents which occurred in 2008, the demand of information on the nuclear risk)

  17. The IRSN 2009 barometer. The opinion on risks and security of the French population. Global results

    International Nuclear Information System (INIS)

    2009-01-01

    This report presents and comments the results of a survey during which a sample of the French population has been questioned on their current concerns (about the society, about the environment, about the image of science), on their opinion on scientific expertise (who should control a risky installation, the role and image of experts, the access to expertise files, the perception of pluralist structures), the opinion on 31 risk situations (risks to which French people feel exposed, confidence in authorities, truth of information on hazards, hierarchy of the 31 situations), the opinion on the nuclear activity and industry (the nuclear risk, the credibility and expertise of interveners, incidents which occurred in 2008, the demand of information on the nuclear risk)

  18. Effects of metals on enantioselective toxicity and biotransformation of cis-bifenthrin in zebrafish.

    Science.gov (United States)

    Yang, Ye; Ji, Dapeng; Huang, Xin; Zhang, Jianyun; Liu, Jing

    2017-08-01

    Co-occurrence of pyrethroids and metals in watersheds previously has been reported to pose great risk to aquatic species. Pyrethroids are a class of chiral insecticides that have been shown to have enantioselective toxicity and biotransformation. However, the influence of metals on enantioselectivity of pyrethroids has not yet been evaluated. In the present study, the effects of cadmium (Cd), copper (Cu), and lead (Pb) on the enantioselective toxicity and metabolism of cis-bifenthrin (cis-BF) were investigated in zebrafish at environmentally relevant concentrations. The addition of Cd, Cu, or Pb significantly increased the mortality of zebrafish in racemate and R-enantiomer of cis-BF-treated groups. In rac-cis-BF- or 1R-cis-BF-treated groups, the addition of Cd, Cu, or Pb caused a decrease in enantiomeric fraction (EF) and an increased ratio of R-enantiomer residues in zebrafish. In 1S-cis-BF-treated groups, coexposure to Cd led to a lower EF and decreased residue levels of S-enantiomer. In addition, coexposure to the 3 metals resulted in different biodegradation characteristics of each enantiomer accompanied with differential changes in the expression of cytochrome P450 (CYP)1, CYP2, and CYP3 genes, which might be responsible for the enantioselective biodegradation of cis-BF in zebrafish. These results suggest that the influence of coexistent metals should be considered in the ecological risk assessment of chiral pyrethroids in aquatic environments. Environ Toxicol Chem 2017;36:2139-2146. © 2017 SETAC. © 2017 SETAC.

  19. Consumer opinions from the question of a wellness and health conservation

    Directory of Open Access Journals (Sweden)

    Mónika Fodor

    2014-07-01

    Full Text Available This paper presents the sub results of our researchproject. The surveys carried outin 2013 with the help of standardised questionnaire. We received 956questionnaires in the course of the domestic data registration, not continuingrepresentative, national sampling. The object of the research was to recognise theconsumers' opinion about wellness, their attitude towards the question of thehealth conservation. We analysed the expenses devoted to the health conservation,and the different kind of activities which has important role in health conservationaccording to consumers’ opinion. We examined whichconcepts, which service elements the people enclose to the wellness, what kind of factors influence themin the course of the selection of a wellness service. We hope the results can helpfor the service providers of domestic health tourism and wellness in their work tomake well targeted marketing activities.

  20. The Role of Cis-Lunar Space in Future Global Space Exploration

    Science.gov (United States)

    Bobskill, Marianne R.; Lupisella, Mark L.

    2012-01-01

    Cis-lunar space offers affordable near-term opportunities to help pave the way for future global human exploration of deep space, acting as a bridge between present missions and future deep space missions. While missions in cis-lunar space have value unto themselves, they can also play an important role in enabling and reducing risk for future human missions to the Moon, Near-Earth Asteroids (NEAs), Mars, and other deep space destinations. The Cis-Lunar Destination Team of NASA's Human Spaceflight Architecture Team (HAT) has been analyzing cis-lunar destination activities and developing notional missions (or "destination Design Reference Missions" [DRMs]) for cis-lunar locations to inform roadmap and architecture development, transportation and destination elements definition, operations, and strategic knowledge gaps. The cis-lunar domain is defined as that area of deep space under the gravitational influence of the earth-moon system. This includes a set of earth-centered orbital locations in low earth orbit (LEO), geosynchronous earth orbit (GEO), highly elliptical and high earth orbits (HEO), earth-moon libration or "Lagrange" points (E-ML1 through E-ML5, and in particular, E-ML1 and E-ML2), and low lunar orbit (LLO). To help explore this large possibility space, we developed a set of high level cis-lunar mission concepts in the form of a large mission tree, defined primarily by mission duration, pre-deployment, type of mission, and location. The mission tree has provided an overall analytical context and has helped in developing more detailed design reference missions that are then intended to inform capabilities, operations, and architectures. With the mission tree as context, we will describe two destination DRMs to LEO and GEO, based on present human space exploration architectural considerations, as well as our recent work on defining mission activities that could be conducted with an EML1 or EML2 facility, the latter of which will be an emphasis of this

  1. The effects of social media opinion leaders’ recommendations on followers’ intention to buy

    Directory of Open Access Journals (Sweden)

    Renata Huhn Nunes

    2018-01-01

    Full Text Available Purpose – The objective of this study is to investigate how consumers are influenced in their intention to buy after having access – within social media – to persuasive messages sent out by digital opinion leaders. Design/methodology/approach – Data collection carried out via survey and data analysis carried out with the use of structural equation modeling. Findings – Digital opinion leaders capable of generating persuasive messages can change the attitudes of followers and make them accept the information provided, influencing their intention to buy evaluated products. Originality/value – The results show that it was possible to verify the direct and positive relationship between the persuasiveness of a message and the acceptance of the information contained in this message, while also indicating a significant relationship between the persuasiveness of the message and attitude change in relation to the purchase of goods evaluated by it. This highlights the relevance of these digital opinion leaders to the definition of marketing strategies by companies.

  2. Opinions of veterinarians on antimicrobial use in farm animals in Flanders and the Netherlands

    NARCIS (Netherlands)

    Speksnijder, D. C.; Jaarsma, A. D. C.; Verheij, T. J. M.; Wagenaar, J. A.; Dewulf, J.

    2016-01-01

    Veterinarians play an important role in the reduction of antimicrobial use in farm animals. This study aims to quantify opinions of veterinarians from the Netherlands and Flanders regarding antimicrobial use and resistance issues in farm animals. An online survey was sent out to 678 and 1100 farm

  3. Investing in CIS: obstacles and strategies

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    The CIS (Community of Independent States) needs the help of foreign investments to develop its huge hydrocarbon potentialities. Because of the uncertainties concerning the legal and fiscal context of their activities, the role of the international oil companies has remained limited so far. These problems were discussed in May 1996 during an important ''General Session'' of the OTC 96 congress. Proven and explored onshore oil reserves in Russia are enormous, in particular in Western and Eastern Siberia. However, the economically most interesting resources are located in the offshore zones of the Barents, Pechora and Kara seas and of Eastern Siberia and Okhotsk. This paper describes the last years decay of oil production in CIS and its causes, in particular the obstacles to foreign investments (exportation and transport taxes), the recent contracts and joint-ventures with American major companies (Exxon, Amoco..), and the situation of the Russian industry in petroleum engineering and field exploitation materials. (J.S.)

  4. Coevolution within a transcriptional network by compensatory trans and cis mutations

    KAUST Repository

    Kuo, D.

    2010-10-26

    Transcriptional networks have been shown to evolve very rapidly, prompting questions as to how such changes arise and are tolerated. Recent comparisons of transcriptional networks across species have implicated variations in the cis-acting DNA sequences near genes as the main cause of divergence. What is less clear is how these changes interact with trans-acting changes occurring elsewhere in the genetic circuit. Here, we report the discovery of a system of compensatory trans and cis mutations in the yeast AP-1 transcriptional network that allows for conserved transcriptional regulation despite continued genetic change. We pinpoint a single species, the fungal pathogen Candida glabrata, in which a trans mutation has occurred very recently in a single AP-1 family member, distinguishing it from its Saccharomyces ortholog. Comparison of chromatin immunoprecipitation profiles between Candida and Saccharomyces shows that, despite their different DNA-binding domains, the AP-1 orthologs regulate a conserved block of genes. This conservation is enabled by concomitant changes in the cis-regulatory motifs upstream of each gene. Thus, both trans and cis mutations have perturbed the yeast AP-1 regulatory system in such a way as to compensate for one another. This demonstrates an example of “coevolution” between a DNA-binding transcription factor and its cis-regulatory site, reminiscent of the coevolution of protein binding partners.

  5. CIS-based registration of quality of life in a single source approach.

    Science.gov (United States)

    Fritz, Fleur; Ständer, Sonja; Breil, Bernhard; Riek, Markus; Dugas, Martin

    2011-04-21

    Documenting quality of life (QoL) in routine medical care and using it both for treatment and for clinical research is not common, although such information is absolutely valuable for physicians and patients alike. We therefore aimed at developing an efficient method to integrate quality of life information into the clinical information system (CIS) and thus make it available for clinical care and secondary use. We piloted our method in three different medical departments, using five different QoL questionnaires. In this setting we used structured interviews and onsite observations to perform workflow and form analyses. The forms and pertinent data reports were implemented using the integrated tools of the local CIS. A web-based application for mobile devices was developed based on XML schemata to facilitate data import into the CIS. Data exports of the CIS were analysed with statistical software to perform an analysis of data quality. The quality of life questionnaires are now regularly documented by patients and physicians. The resulting data is available in the Electronic Health Record (EHR) and can be used for treatment purposes and communication as well as research functionalities. The completion of questionnaires by the patients themselves using a mobile device (iPad) and the import of the respective data into the CIS forms were successfully tested in a pilot installation. The quality of data is rendered high by the use of automatic score calculations as well as the automatic creation of forms for follow-up documentation. The QoL data was exported to research databases for use in scientific analysis. The CIS-based QoL is technically feasible, clinically accepted and provides an excellent quality of data for medical treatment and clinical research. Our approach with a commercial CIS and the web-based application is transferable to other sites.

  6. Studies of Binary Complexes of Tripodal Ligand cis,cis-1,3,5-tris(methylaminocyclohexane with Cr(III and Fe(III

    Directory of Open Access Journals (Sweden)

    S. Esakki Muthu

    2005-01-01

    Full Text Available The formation of binary complexes of Cr(III and Fe(III with a tripodal ligand cis,cis-1,3,5-tris(methylaminocyclohexane (tmach (L has been investigated in solution. The overall stability constants of tmach with Cr(III and Fe(III were determined by potentiometric method at an ionic strength of 0.1 M NaClO4 at 25±1°C in aqueous medium. The formation of species like MLH25+, MLH4+, ML3+, ML(OH2+ and ML(OH3 were observed. Fe(III was found to form more stable complexes than Cr(III. Molecular mechanics calculations were performed to explain the mode of coordination in solution.

  7. Single d(ApG)/cis-diamminedichloroplatinum(II) adduct-induced mutagenesis in Escherichia coli

    International Nuclear Information System (INIS)

    Burnouf, D.; Fuchs, R.P.P.; Gauthier, C.; Chottard, J.C.

    1990-01-01

    The mutation spectrum induced by the widely used antitumor drug cis-diamminedichloroplatinum(II) (cis-DDP) showed that cisDDP[d(ApG)] adducts, although they account for only 25% of the lesions formed are ∼5 times more mutagenic than the major GG adduct. The authors report the construction of vectors bearing a single cisDDP[d(ApG)] lesion and their use in mutagenesis experiments in Escherichia coli. The mutagenic processing of the lesion is found to depend strictly on induction of the SOS system of the bacterial host cells. In SOS-induced cells, mutation frequencies of 1-2% were detected. All these mutations are targeted to the 5' base of the adduct. Single A → T transversions are mainly observed (80%), whereas A → G transitions account for 10% of the total mutations. Tandem base-pair substitutions involving the adenine residue and the thymine residue immediately 5' to the adduct occur at a comparable frequency (10%). No selective loss of the strand bearing the platinum adduct was seen, suggesting that, in vivo, cisDDP[d(ApG)] adducts are not blocking lesions. The high mutation specificity of cisDDP-[d(ApG)]-induced mutagenesis is discussed in relation to structural data

  8. Results of the 2008/2009 Knowledge and Opinions Surveys Conducted for the U.S. Department of Energy Hydrogen Program

    Energy Technology Data Exchange (ETDEWEB)

    Schmoyer, Richard L [ORNL; Truett, Lorena Faith [ORNL; Cooper, Christy [U.S. Department of Energy; Chew, Andrea [U.S. Department of Energy

    2010-04-01

    The U.S. Department of Energy (DOE) Fuel Cell Technologies Program (FCT) conducts comprehensive efforts to enable the widespread commercialization of fuel cells in diverse sectors of the economy - with emphasis on applications that will most effectively strengthen our nation's energy security and improve our stewardship of the environment. Expanding the use of fuel cells requires a sustained education effort to lay the foundation for future commercial market introduction. The FCT education subprogram seeks to facilitate fuel cell demonstrations and support future commercialization by providing technically accurate and objective information to key target audiences both directly and indirectly involved in the use of fuel cells today. These key target audiences include a public that is familiar and comfortable with using a new fuel, state and local government officials who understand the near-term realities and long-term potential of the technology, an educated business and industry component, and trained safety and codes officials. With this in mind, the DOE FCT program established an education key activity to address the training and informational needs of target audiences that have a role in the near-term transition and the long-term development of a hydrogen economy. Whether or not changes can be attributed to the program, designing and maintaining an effective education program entails measuring baseline awareness and periodically measuring what has been learned. The purpose of this report is to document the data and results of statistical surveys undertaken in 2008 and 2009 to measure and establish changes in understanding and awareness about hydrogen and fuel cell technologies since a baseline survey was conducted in 2004. This report is essentially a data book, a digest of the survey data and an exposition of changes in knowledge of and opinions about hydrogen and fuel cell technology since 2004. Many conclusions can be made from the survey data. However

  9. Public opinions and antinuclear contestations

    International Nuclear Information System (INIS)

    Silveira, P.R.N. da

    1978-01-01

    With the aim of demonstrating the importance of public opinion in the development of a nuclear program, a historical analysis of the different forms of anti-technological reactions is shown, starting with a study of the general aspects of mass communication and public opinion. The world-wide communication strategy adopted in the implantation of nuclear programs is discussed and, finally, the nuclear energy issue and public opinion in Brazil are analysed. (F.E.) [pt

  10. Opinions in Denmark on the causes of peptic ulcer disease. A survey among Danish physicians and patients

    DEFF Research Database (Denmark)

    Christensen, A H; Gjørup, T; Andersen, I B

    1994-01-01

    of medicine, and working conditions played a causal role. Around 95% of the physicians indicated that medical drugs and smoking were contributory causes of peptic ulcer disease, and around 80% that alcohol and psychologic factors were so. Only 30-40% of the physicians believed that coffee/tea, food habits...... stated more causes than did their male colleagues (p smoking, side effects......, infection, and working conditions could play a causal role in ulcer disease. It is concluded that the opinion on causal agents in peptic ulcer disease differ considerably among both patients and physicians. Opinions on causes of diseases may influence the way we treat and advise our patients, and attempts...

  11. Choice Shift in Opinion Network Dynamics

    Science.gov (United States)

    Gabbay, Michael

    Choice shift is a phenomenon associated with small group dynamics whereby group discussion causes group members to shift their opinions in a more extreme direction so that the mean post-discussion opinion exceeds the mean pre-discussion opinion. Also known as group polarization, choice shift is a robust experimental phenomenon and has been well-studied within social psychology. In opinion network models, shifts toward extremism are typically produced by the presence of stubborn agents at the extremes of the opinion axis, whose opinions are much more resistant to change than moderate agents. However, we present a model in which choice shift can arise without the assumption of stubborn agents; the model evolves member opinions and uncertainties using coupled nonlinear differential equations. In addition, we briefly describe the results of a recent experiment conducted involving online group discussion concerning the outcome of National Football League games are described. The model predictions concerning the effects of network structure, disagreement level, and team choice (favorite or underdog) are in accord with the experimental results. This research was funded by the Office of Naval Research and the Defense Threat Reduction Agency.

  12. Women's opinions of legal requirements for drug testing in prenatal care.

    Science.gov (United States)

    Tucker Edmonds, Brownsyne; Mckenzie, Fatima; Austgen, MacKenzie B; Carroll, Aaron E; Meslin, Eric M

    2017-07-01

    To explore women's attitudes and perceptions regarding legal requirements for prenatal drug testing. Web-based survey of 500 US women (age 18-45) recruited from a market research survey panel. A 24-item questionnaire assessed their opinion of laws requiring doctors to routinely verbal screen and urine drug test patients during pregnancy; recommendations for consequences for positive drug tests during pregnancy; and opinion of laws requiring routine drug testing of newborns. Additional questions asked participants about the influence of such laws on their own care-seeking behaviors. Data were analyzed for associations between participant characteristics and survey responses using Pearson's chi-squared test. The majority of respondents (86%) stated they would support a law requiring verbal screening of all pregnant patients and 73% would support a law requiring universal urine drug testing in pregnancy. Fewer respondents were willing to support laws that required verbal screening or urine drug testing (68% and 61%, respectively) targeting only Medicaid recipients. Twenty-one percent of respondents indicated they would be offended if their doctors asked them about drug use and 14% indicated that mandatory drug testing would discourage prenatal care attendance. Women would be more supportive of policies requiring universal rather than targeted screening and testing for prenatal drug use. However, a noteworthy proportion of women would be discouraged from attending prenatal care - a reminder that drug testing policies may have detrimental effects on maternal child health.

  13. Opinions and practices of medical rehabilitation professionals regarding prayer and meditation.

    Science.gov (United States)

    Schoenberger, Nancy E; Matheis, Robert J; Shiflett, Samuel C; Cotter, Ann C

    2002-02-01

    To assess the attitudes and practices of professionals in the field of physical medicine and rehabilitation (PM&R) regarding prayer and meditation. A national mail survey that included questions about the use of a number of complementary and alternative therapies. The survey was mailed to 7,479 physicians, nurses, physical therapists, and occupational therapists who specialize in PM&R, and 1221 (17%) returned completed surveys. Although the majority of respondents endorsed prayer as a legitimate health care practice, there was greater belief in the benefits of meditation. Older respondents were more likely to recommend meditation to their patients and more likely to meditate themselves. Gender differences that were observed in opinions and practices are better interpreted as differences in professional specialty. In general, nurses and occupational therapists responded more positively toward meditation and prayer than did physicians and physical therapists. Personal use of a technique was the strongest predictor of professional behaviors. Attitude was a stronger predictor of professional use or referral for prayer than meditation, but correlations between attitude and behavior were generally weak for both techniques. Despite their acceptance of these techniques, the vast majority of rehabilitation professionals did not refer their patients for meditation or religious consultation. Although there were significant relationships among beliefs, and personal and professional behaviors regarding these techniques, a large part of the variance in professional behaviors was not accounted for by age, gender, opinion, or personal behavior, indicating that other influences exert a stronger effect on professional practice decisions.

  14. Opinion dynamics with confirmation bias.

    Directory of Open Access Journals (Sweden)

    Armen E Allahverdyan

    Full Text Available Confirmation bias is the tendency to acquire or evaluate new information in a way that is consistent with one's preexisting beliefs. It is omnipresent in psychology, economics, and even scientific practices. Prior theoretical research of this phenomenon has mainly focused on its economic implications possibly missing its potential connections with broader notions of cognitive science.We formulate a (non-Bayesian model for revising subjective probabilistic opinion of a confirmationally-biased agent in the light of a persuasive opinion. The revision rule ensures that the agent does not react to persuasion that is either far from his current opinion or coincides with it. We demonstrate that the model accounts for the basic phenomenology of the social judgment theory, and allows to study various phenomena such as cognitive dissonance and boomerang effect. The model also displays the order of presentation effect-when consecutively exposed to two opinions, the preference is given to the last opinion (recency or the first opinion (primacy -and relates recency to confirmation bias. Finally, we study the model in the case of repeated persuasion and analyze its convergence properties.The standard Bayesian approach to probabilistic opinion revision is inadequate for describing the observed phenomenology of persuasion process. The simple non-Bayesian model proposed here does agree with this phenomenology and is capable of reproducing a spectrum of effects observed in psychology: primacy-recency phenomenon, boomerang effect and cognitive dissonance. We point out several limitations of the model that should motivate its future development.

  15. Trendwatch combining expert opinion

    NARCIS (Netherlands)

    Hendrix, E.M.T.; Kornelis, M.; Pegge, S.M.; Galen, van M.A.

    2006-01-01

    In this study, focus is on a systematic way to detect future changes in trends that may effect the dynamics in the agro-food sector, and on the combination of opinions of experts. For the combination of expert opinions, the usefulness of multilevel models is investigated. Bayesian data analysis is

  16. Expert Opinion Is Necessary: Delphi Panel Methodology Facilitates a Scientific Approach to Consensus.

    Science.gov (United States)

    Hohmann, Erik; Brand, Jefferson C; Rossi, Michael J; Lubowitz, James H

    2018-02-01

    Our current trend and focus on evidence-based medicine is biased in favor of randomized controlled trials, which are ranked highest in the hierarchy of evidence while devaluing expert opinion, which is ranked lowest in the hierarchy. However, randomized controlled trials have weaknesses as well as strengths, and no research method is flawless. Moreover, stringent application of scientific research techniques, such as the Delphi Panel methodology, allows survey of experts in a high quality and scientific manner. Level V evidence (expert opinion) remains a necessary component in the armamentarium used to determine the answer to a clinical question. Copyright © 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  17. Strand-specific RNA-seq reveals widespread occurrence of novel cis-natural antisense transcripts in rice

    Directory of Open Access Journals (Sweden)

    Lu Tingting

    2012-12-01

    Full Text Available Abstract Background Cis-natural antisense transcripts (cis-NATs are RNAs transcribed from the antisense strand of a gene locus, and are complementary to the RNA transcribed from the sense strand. Common techniques including microarray approach and analysis of transcriptome databases are the major ways to globally identify cis-NATs in various eukaryotic organisms. Genome-wide in silico analysis has identified a large number of cis-NATs that may generate endogenous short interfering RNAs (nat-siRNAs, which participate in important biogenesis mechanisms for transcriptional and post-transcriptional regulation in rice. However, the transcriptomes are yet to be deeply sequenced to comprehensively investigate cis-NATs. Results We applied high-throughput strand-specific complementary DNA sequencing technology (ssRNA-seq to deeply sequence mRNA for assessing sense and antisense transcripts that were derived under salt, drought and cold stresses, and normal conditions, in the model plant rice (Oryza sativa. Combined with RAP-DB genome annotation (the Rice Annotation Project Database build-5 data set, 76,013 transcripts corresponding to 45,844 unique gene loci were assembled, in which 4873 gene loci were newly identified. Of 3819 putative rice cis-NATs, 2292 were detected as expressed and giving rise to small RNAs from their overlapping regions through integrated analysis of ssRNA-seq data and small RNA data. Among them, 503 cis-NATs seemed to be associated with specific conditions. The deep sequence data from isolated epidermal cells of rice seedlings further showed that 54.0% of cis-NATs were expressed simultaneously in a population of homogenous cells. Nearly 9.7% of rice transcripts were involved in one-to-one or many-to-many cis-NATs formation. Furthermore, only 17.4-34.7% of 223 many-to-many cis-NAT groups were all expressed and generated nat-siRNAs, indicating that only some cis-NAT groups may be involved in complex regulatory networks. Conclusions

  18. STEM field courses that increase interest, opinions and confidence in conservation- related fields

    Science.gov (United States)

    Christensen, B. A.; Freeman, A. S.; Donovan, C.; Cooperstein, D.; Foellmer, M.; Ward, A.

    2016-12-01

    Students in the Environmental Studies and Biology programs at Adelphi University, situated in the NYC metropolitan area, have had little exposure to the outdoors or nature and are often reluctant to engage in field activities. We developed three courses to provide outdoor experiences at different levels of intensity, financial and travel/ time commitments. Adelphi in Australia is a three-week field course taught mostly at a marine station that includes day and night hikes, snorkeling on the Great Barrier Reef (GBR) and independent research. Adelphi in the U.S. Virgin Islands is a one-week field `starter course' focusing on snorkeling and hiking. Observing Nature is an on-campus, once a week course with nature-based readings, weekend hikes and camping. It was developed after Hurricane Sandy revealed a lack of experience and confidence living without some modern infrastructure. We evaluated student opinions, interests and career goals in a survey administered at the start and at the end of the course that focused on knowledge, skills, opinion, and interest in STEM. Opinion questions addressed confidence, awareness of conservation issues, and interest in outdoor activities. The survey confirmed most of our students have a limited relationship with the outdoors when they start our field classes. More than half had never camped. Most had learned about nature through school trips and family. When asked to rank hiking against other activities, the majority regularly placed hiking below `going to the beach' and 'watching a movie'. The post-survey asked how students would apply what they had learned (interest in the environment; staying in the sciences). The generally positive results indicate the courses play an important role in connecting our students with the outdoors, and may have a lasting impact if they in turn connect others or get involved with local conservation programs.

  19. Climate of opinion and information behaviour in the context of nuclear energy and the ENSI

    International Nuclear Information System (INIS)

    Bonfadelli, H.; Kristiansen, S.

    2012-11-01

    This interim report issued by the University of Zurich for the Swiss Federal Nuclear Safety Inspectorate (ENSI) was elaborated as a result of the nuclear accident in Fukushima, Japan. The report discusses the questions raised concerning the independence of certain members of the inspectorate and discusses the results of an initial survey on the profile and reputation of the inspectorate. The development of public opinion concerning various aspects of nuclear energy over several years and for various categories of the population is noted in tables. Also, large changes in opinion after the Fukushima accident are noted. Risk assessments, confidence in the regulatory instances as well as opinions on how nuclear energy should be regulated are examined. Also, information and media use in connection with nuclear energy are looked at. Finally, the most important conclusions of the study are presented and discussed

  20. OpinionSeer: interactive visualization of hotel customer feedback.

    Science.gov (United States)

    Wu, Yingcai; Wei, Furu; Liu, Shixia; Au, Norman; Cui, Weiwei; Zhou, Hong; Qu, Huamin

    2010-01-01

    The rapid development of Web technology has resulted in an increasing number of hotel customers sharing their opinions on the hotel services. Effective visual analysis of online customer opinions is needed, as it has a significant impact on building a successful business. In this paper, we present OpinionSeer, an interactive visualization system that could visually analyze a large collection of online hotel customer reviews. The system is built on a new visualization-centric opinion mining technique that considers uncertainty for faithfully modeling and analyzing customer opinions. A new visual representation is developed to convey customer opinions by augmenting well-established scatterplots and radial visualization. To provide multiple-level exploration, we introduce subjective logic to handle and organize subjective opinions with degrees of uncertainty. Several case studies illustrate the effectiveness and usefulness of OpinionSeer on analyzing relationships among multiple data dimensions and comparing opinions of different groups. Aside from data on hotel customer feedback, OpinionSeer could also be applied to visually analyze customer opinions on other products or services.

  1. Whole-body kinetics and dosimetry of cis-4-[{sup 18}F]fluoro-l-proline

    Energy Technology Data Exchange (ETDEWEB)

    Boerner, Anne R.; Langen, Karl-J. E-mail: k.j.langen@fz-juelich.de; Herzog, Hans; Hamacher, Kurt; Mueller-Mattheis, Volker; Schmitz, Thomas; Ackermann, Rolf; Coenen, Heinz H

    2001-04-01

    The whole-body distribution of 4-cis[{sup 18}F]fluoro-L-proline (cis-FPro) was studied in six patients with urological tumors by PET. Based on the IMEDOSE and MIRDOSE procedures radiation absorbed doses were estimated from whole-body PET scans acquired at 1 and 3-5 h after i.v. injection of 400 MBq cis-FPro. Cis-FPro showed high retention in the renal cortex and a slight uptake in liver and pancreas. Urinary excretion ranged from 12 to 19% at 5 h p.i. Highest absorbed doses were found for the urinary bladder wall and the kidneys (44.1/44.0 {mu}Gy/MBq). The effective dose according to ICRP 60 was 15.1 {mu}Sv/MBq for adults. This leads to an effective dose of 6.0 mSv in a PET study using 400 MBq cis-FPro.

  2. Ethical Challenges of Educational Leadership in the Countries of the CIS

    Science.gov (United States)

    Zagoumennov, Iouri

    2010-01-01

    There is no school administrators' pre-service training in the CIS (Former USSR) countries. As for the in-service training, it has been traditionally focused on educational management. As a result, schools in the CIS countries are run as well-oiled machines but there is a big question mark over whether these machines are running in the right…

  3. The use of online word of mouth opinion in online learning: a questionnaire survey.

    Science.gov (United States)

    Sandars, John; Walsh, Kieran

    2009-04-01

    There is increasing use of online word of mouth opinion (user feedback) systems for general services but its use in online learning has not been previously investigated. To understand why users of BMJ Learning provide and read word of mouth feedback, and whether this feedback influences uptake of modules by prospective users. Online questionnaire of users of BMJ Learning who had completed online user feedback. 109 questionnaires were completed (response rate 25%). The main motivation to contribute was to influence the authors of the module (66%), and 43% stated that they wanted to help other users to make an informed choice. 16% stated that they wanted to develop an online community of learners. The main motivation to read the user feedback was to see if they agreed with the comments (56%). Online word of mouth opinion (user feedback) appears to be useful for online learners. There are also system design considerations since the attempt to create an online community of learners that is desired by some users will not be appreciated by others. Further research with a larger number of users is recommended to confirm the findings.

  4. Quality of courses evaluated by 'predictions' rather than opinions: Fewer respondents needed for similar results.

    Science.gov (United States)

    Cohen-Schotanus, Janke; Schönrock-Adema, Johanna; Schmidt, Henk G

    2010-01-01

    A well-known problem with student surveys is a too low response rate. Experiences with predicting electoral outcomes, which required much smaller sample sizes, inspired us to adopt a similar approach to course evaluation. We expected that having respondents estimate the average opinions of their peers required fewer respondents for comparable outcomes than giving own opinions. Two course evaluation studies were performed among successive first-year medical students (N = 380 and 450, respectively). Study 1: Half the cohort gave opinions on nine questions, while the other half predicted the average outcomes. A prize was offered for the three best predictions (motivational remedy). Study 2: Half the cohort gave opinions, a quarter made predictions without a prize and a quarter made predictions with previous year's results as prior knowledge (cognitive remedy). The numbers of respondents required for stable outcomes were determined following an iterative process. Differences between numbers of respondents required and between average scores were analysed with ANOVA. In both studies, the prediction conditions required significantly fewer respondents (p < 0.001) for comparable outcomes. The informed prediction condition required the fewest respondents (N < 20). Problems with response rates can be reduced by asking respondents to predict evaluation outcomes rather than giving opinions.

  5. Cis-regulatory somatic mutations and gene-expression alteration in B-cell lymphomas.

    Science.gov (United States)

    Mathelier, Anthony; Lefebvre, Calvin; Zhang, Allen W; Arenillas, David J; Ding, Jiarui; Wasserman, Wyeth W; Shah, Sohrab P

    2015-04-23

    With the rapid increase of whole-genome sequencing of human cancers, an important opportunity to analyze and characterize somatic mutations lying within cis-regulatory regions has emerged. A focus on protein-coding regions to identify nonsense or missense mutations disruptive to protein structure and/or function has led to important insights; however, the impact on gene expression of mutations lying within cis-regulatory regions remains under-explored. We analyzed somatic mutations from 84 matched tumor-normal whole genomes from B-cell lymphomas with accompanying gene expression measurements to elucidate the extent to which these cancers are disrupted by cis-regulatory mutations. We characterize mutations overlapping a high quality set of well-annotated transcription factor binding sites (TFBSs), covering a similar portion of the genome as protein-coding exons. Our results indicate that cis-regulatory mutations overlapping predicted TFBSs are enriched in promoter regions of genes involved in apoptosis or growth/proliferation. By integrating gene expression data with mutation data, our computational approach culminates with identification of cis-regulatory mutations most likely to participate in dysregulation of the gene expression program. The impact can be measured along with protein-coding mutations to highlight key mutations disrupting gene expression and pathways in cancer. Our study yields specific genes with disrupted expression triggered by genomic mutations in either the coding or the regulatory space. It implies that mutated regulatory components of the genome contribute substantially to cancer pathways. Our analyses demonstrate that identifying genomically altered cis-regulatory elements coupled with analysis of gene expression data will augment biological interpretation of mutational landscapes of cancers.

  6. Genome-wide haplotype analysis of cis expression quantitative trait loci in monocytes.

    Directory of Open Access Journals (Sweden)

    Sophie Garnier

    Full Text Available In order to assess whether gene expression variability could be influenced by several SNPs acting in cis, either through additive or more complex haplotype effects, a systematic genome-wide search for cis haplotype expression quantitative trait loci (eQTL was conducted in a sample of 758 individuals, part of the Cardiogenics Transcriptomic Study, for which genome-wide monocyte expression and GWAS data were available. 19,805 RNA probes were assessed for cis haplotypic regulation through investigation of ~2,1 × 10(9 haplotypic combinations. 2,650 probes demonstrated haplotypic p-values >10(4-fold smaller than the best single SNP p-value. Replication of significant haplotype effects were tested for 412 probes for which SNPs (or proxies that defined the detected haplotypes were available in the Gutenberg Health Study composed of 1,374 individuals. At the Bonferroni correction level of 1.2 × 10(-4 (~0.05/412, 193 haplotypic signals replicated. 1000 G imputation was then conducted, and 105 haplotypic signals still remained more informative than imputed SNPs. In-depth analysis of these 105 cis eQTL revealed that at 76 loci genetic associations were compatible with additive effects of several SNPs, while for the 29 remaining regions data could be compatible with a more complex haplotypic pattern. As 24 of the 105 cis eQTL have previously been reported to be disease-associated loci, this work highlights the need for conducting haplotype-based and 1000 G imputed cis eQTL analysis before commencing functional studies at disease-associated loci.

  7. Are opinions based on science: modelling social response to scientific facts.

    Directory of Open Access Journals (Sweden)

    Gerardo Iñiguez

    Full Text Available As scientists we like to think that modern societies and their members base their views, opinions and behaviour on scientific facts. This is not necessarily the case, even though we are all (over- exposed to information flow through various channels of media, i.e. newspapers, television, radio, internet, and web. It is thought that this is mainly due to the conflicting information on the mass media and to the individual attitude (formed by cultural, educational and environmental factors, that is, one external factor and another personal factor. In this paper we will investigate the dynamical development of opinion in a small population of agents by means of a computational model of opinion formation in a co-evolving network of socially linked agents. The personal and external factors are taken into account by assigning an individual attitude parameter to each agent, and by subjecting all to an external but homogeneous field to simulate the effect of the media. We then adjust the field strength in the model by using actual data on scientific perception surveys carried out in two different populations, which allow us to compare two different societies. We interpret the model findings with the aid of simple mean field calculations. Our results suggest that scientifically sound concepts are more difficult to acquire than concepts not validated by science, since opposing individuals organize themselves in close communities that prevent opinion consensus.

  8. Oxidation reactions of derivatives of cis-octalins promoted by thallium trinitrate (TTN)

    International Nuclear Information System (INIS)

    Ferraz, Helena M.C.; Carneiro, Vania M.T.; Vieira, Tiago O.; Silva Junior, Luiz F.

    2008-01-01

    The reaction of ten cis-octalins and cis-octalones with thallium trinitrate (TTN) leads to different products, depending mainly on the substitution pattern of the substrate. Functionalized cis-hydrindanes were obtained from the reaction of 1,2,3,4,4a,5,8,8a-octahydro- 4a-methylnaphthalene and of 1,2,3,4,4a,5,8,8a-octahydro-4a,7-dimethylnaphthalene with TTN in acetonitrile, whereas a cyclic ether was formed treating 1,2,3,4,4a,5,8,8a-octahydro-6,8a-dimethylnaphthalene-1-ol with TTN in trimethylorthoformate (TMOF). (author)

  9. Designing Graduate-Level Plant Breeding Curriculum: A Delphi Study of Private Sector Stakeholder Opinions

    Science.gov (United States)

    Miller, Jane K.; Repinski, Shelby L.; Hayes, Kathryn N.; Bliss, Frederick A.; Trexler, Cary J.

    2011-01-01

    A broad-based survey using the Delphi method was conducted to garner current information from private sector stakeholders and build consensus opinions supporting key ideas for enhancing plant breeder education and training. This study asked respondents to suggest and rate topics and content they deemed most important to plant breeding graduate…

  10. On the Concept of Cis-regulatory Information: From Sequence Motifs to Logic Functions

    Science.gov (United States)

    Tarpine, Ryan; Istrail, Sorin

    The regulatory genome is about the “system level organization of the core genomic regulatory apparatus, and how this is the locus of causality underlying the twin phenomena of animal development and animal evolution” (E.H. Davidson. The Regulatory Genome: Gene Regulatory Networks in Development and Evolution, Academic Press, 2006). Information processing in the regulatory genome is done through regulatory states, defined as sets of transcription factors (sequence-specific DNA binding proteins which determine gene expression) that are expressed and active at the same time. The core information processing machinery consists of modular DNA sequence elements, called cis-modules, that interact with transcription factors. The cis-modules “read” the information contained in the regulatory state of the cell through transcription factor binding, “process” it, and directly or indirectly communicate with the basal transcription apparatus to determine gene expression. This endowment of each gene with the information-receiving capacity through their cis-regulatory modules is essential for the response to every possible regulatory state to which it might be exposed during all phases of the life cycle and in all cell types. We present here a set of challenges addressed by our CYRENE research project aimed at studying the cis-regulatory code of the regulatory genome. The CYRENE Project is devoted to (1) the construction of a database, the cis-Lexicon, containing comprehensive information across species about experimentally validated cis-regulatory modules; and (2) the software development of a next-generation genome browser, the cis-Browser, specialized for the regulatory genome. The presentation is anchored on three main computational challenges: the Gene Naming Problem, the Consensus Sequence Bottleneck Problem, and the Logic Function Inference Problem.

  11. Opinion formation models on a gradient.

    Directory of Open Access Journals (Sweden)

    Michael T Gastner

    Full Text Available Statistical physicists have become interested in models of collective social behavior such as opinion formation, where individuals change their inherently preferred opinion if their friends disagree. Real preferences often depend on regional cultural differences, which we model here as a spatial gradient g in the initial opinion. The gradient does not only add reality to the model. It can also reveal that opinion clusters in two dimensions are typically in the standard (i.e., independent percolation universality class, thus settling a recent controversy about a non-consensus model. However, using analytical and numerical tools, we also present a model where the width of the transition between opinions scales proportional g(-1/4, not proportional g(-4/7 as in independent percolation, and the cluster size distribution is consistent with first-order percolation.

  12. Public opinion change after the Fukushima nuclear accident: The role of national context revisited

    International Nuclear Information System (INIS)

    Latré, Edwin; Perko, Tanja; Thijssen, Peter

    2017-01-01

    This study explores how national context moderated change in support for nuclear energy after the Fukushima accident. The following national contextual variables are tested: geographical distance, nuclear energy production status, freedom of the press, and the building of new nuclear reactors. The results illustrate that previous research has misunderstood the moderating role of national context on opinion change after the Fukushima accident. A survey conducted shortly after the accident with more than 23,000 respondents from 41 countries has shown that geographical distance from the accident mattered: Contradicting a previous study, the decrease in support for nuclear energy was stronger in countries closer to Fukushima. In addition, support for nuclear energy decreased more in countries where new nuclear reactors were under construction. The country's nuclear energy production status and press freedom did not determine opinion change after the Fukushima accident. The non-effect of freedom of the press on opinion change contradicts the role of media after a focusing event as described in the literature. Overall results demonstrate a limited effect of national context on opinion change following a focusing event. Hence, national context provides only limited information to policy makers on how to respond to a nuclear accident. - Highlights: • National context had limited effect on opinion change after Fukushima. • Support for nuclear energy decreased more in counties closer to the accident. • Support for nuclear energy decreased more where the nuclear energy debate was salient. • Freedom of the press did not determine opinion change after Fukushima. • Not all contextual factors are relevant when designing appropriate policy response.

  13. Organization of cis-acting regulatory elements in osmotic- and cold-stress-responsive promoters.

    Science.gov (United States)

    Yamaguchi-Shinozaki, Kazuko; Shinozaki, Kazuo

    2005-02-01

    cis-Acting regulatory elements are important molecular switches involved in the transcriptional regulation of a dynamic network of gene activities controlling various biological processes, including abiotic stress responses, hormone responses and developmental processes. In particular, understanding regulatory gene networks in stress response cascades depends on successful functional analyses of cis-acting elements. The ever-improving accuracy of transcriptome expression profiling has led to the identification of various combinations of cis-acting elements in the promoter regions of stress-inducible genes involved in stress and hormone responses. Here we discuss major cis-acting elements, such as the ABA-responsive element (ABRE) and the dehydration-responsive element/C-repeat (DRE/CRT), that are a vital part of ABA-dependent and ABA-independent gene expression in osmotic and cold stress responses.

  14. Distinctive role of opinion leaders in the social networks of school adolescents: an investigation of e-cigarette use.

    Science.gov (United States)

    Gentina, E; Kilic, D; Dancoine, P-F

    2017-03-01

    This study examines a diverse set of social motives (e.g. peer support, peer pressure, social loneliness) for e-cigarette use, through the mediating effects of opinion leadership, among both male and female adolescents. Prospective cohort study. The data were obtained from a survey conducted among 666 adolescents across 14 school classes, namely, students at three urban schools, public and private, in Lille, France. The proposed integrative model includes social motives, opinion leadership and e-cigarette use in a trilateral relationship; gender is proposed and tested as a potential moderator in a structural equation model. More positive peer support is negatively associated with opinion leadership and e-cigarette use. Both loneliness and susceptibility to peer influence are positively related to opinion leadership and e-cigarette use. Moreover, social support from peers and opinion leadership shape e-cigarette use differently across genders. Policy makers should account for the various (positive and negative) roles of peers and consider the gender of their audience when designing anti-e-cigarette policies. Copyright © 2016 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  15. Molecular mechanism of 9-cis-retinoic acid inhibition of adipogenesis in 3T3-L1 cells

    International Nuclear Information System (INIS)

    Sagara, Chiaki; Takahashi, Katsuhiko; Kagechika, Hiroyuki; Takahashi, Noriko

    2013-01-01

    Highlights: ► We examined the effects of 9-cis-RA on adipogenesis in mouse preadipocyte 3T3-L1. ► 9-cis-RA inhibited lipid accumulation in adipogenetically-induced 3T3-L1 cells. ► A RXR pan-antagonist suppressed the inhibitory effects of 9-cis-RA on adipogenesis. ► This antagonist had no effects on RXRα and PPARγ levels in 9-cis-RA-treated cells. ► 9-cis-RA-induced decrease in both RXRα and PPARγ was independent of RXR activation. -- Abstract: Retinoic acid (RA) signaling is mediated by specific nuclear hormone receptors. Here we examined the effects of 9-cis-RA on adipogenesis in mouse preadipocyte 3T3-L1 cells. 9-cis-RA inhibits the lipid accumulation of adipogenetically induced 3T3-L1 cells. The complex of retinoid X receptor α (RXRα) with peroxisome proliferator-activated receptor γ (PPARγ) is a major transcription factor in the process of adipogenesis, and the levels of these molecules were decreased by 9-cis-RA treatment. A RXR pan-antagonist suppressed 9-cis-RA’s inhibitory effects on adipogenesis, but not on the intracellular levels of both RXRα and PPARγ. These results suggest that 9-cis-RA could inhibit adipogenesis by activating RXR, and decrease both RXR and PPARγs levels in a RXR activation-independent manner

  16. [Medical data security in medico-legal opinioning].

    Science.gov (United States)

    Susło, Robert; Swiatek, Barbara

    2005-01-01

    Medical data security can be approached in medico-legal opinioning in three main situations: security of medical data, on which the opinion should be based, opinioning itself and whether the medical data security was properly ensured and ensuring medical data security during medico-legal opinion giving. The importance of medical data security, during collecting, processing and storing, as well in medical as in legal institutions, is of major importance for the possibility of providing a proper medico-legal opinion. Theoretically speeking, it is possible to give a proper medico-legal opinion using incorrect data, but the possibility is low. When the expert is given improper, unreadable, incomplete or even bogus in part or in the whole medical data it is extremely possible, that he fails in giving his opinion. The term "medical data" was defined and subsequently there was a brief review of medical data storing methods made and specific threats bound with them, based on modern literature. The authors also pointed out possible methods of preventing the threats. They listed Polish as well as international regulations and laws concerning the problem, accenting the importance of preserving medical data for the purposes of medico-legal opinioning.

  17. This kind of 'Asparagus' is quite well liked - Wind energy opinion poll

    International Nuclear Information System (INIS)

    Gutknecht, B.

    2002-01-01

    This article discusses the results of a survey made on the public acceptance of wind energy projects in Switzerland and examines the situation in Switzerland with respect to the use of wind power and its promotion. The results of an internet-based survey made within the framework of a dissertation presented at the Swiss Federal Institute of Technology are presented. This work included 3-D visualisations of proposed wind energy installations at various locations. The results of the survey, which showed a high level of acceptance for the installations, are commented on. The author discusses the ecological considerations relevant to the planning of wind turbines and is of the opinion that there is no danger of wind power installations 'shooting up like asparagus' in the Swiss landscape

  18. Dramatically Polarized Opinion on the Role of Brachytherapy Boost in Management of High-risk Prostate Cancer: A Survey of North American Genitourinary Expert Radiation Oncologists.

    Science.gov (United States)

    McClelland, Shearwood; Sandler, Kiri A; Degnin, Catherine; Chen, Yiyi; Mitin, Timur

    2018-06-01

    Three randomized clinical trials have established brachytherapy (BT) boost in combination with external beam radiation therapy (EBRT) and androgen deprivation therapy (ADT) as superior to definitive EBRT and ADT alone in terms of biochemical control (but not overall survival) at the expense of increased toxicity in men with high-risk (HR) prostate cancer (PCa). The current view regarding these 2 treatment algorithms among North American genitourinary (GU) experts is not known. A survey was distributed to 88 practicing North American GU physicians serving on decision-making committees of cooperative group research organizations. Questions pertained to opinions regarding BT as monotherapy for low-risk PCa and BT boost for HR PCa. Responders were asked to self-identify as BT experts versus non-experts. Treatment recommendations were correlated with practice patterns using the Fisher exact test. Forty-two radiation oncologists completed the survey, of whom 23 (55%) recommend EBRT and ADT alone and 19 (45%) recommend addition of BT boost. Twenty-five participants (60%) identified themselves as BT experts. Nearly 90% of those recommending BT boost were BT experts versus approximately 10% of non-BT experts (P < .001). Responders who recommended BT monotherapy as first-choice treatment for low-risk PCa were more likely to recommend BT boost for HR PCa (P < .0001). There is a dramatic polarization in opinions regarding incorporation of BT boost into EBRT + ADT therapy for patients with HR PCa among North American GU radiation oncology experts, who serve on decision-making committees and influence the national treatment guidelines and future clinical trials. Those who identify themselves as BT experts are significantly more likely to recommend BT boost. These findings are likely to influence the national guidelines and implementation of BT boost in current and future North American PCa clinical studies. Copyright © 2018 Elsevier Inc. All rights reserved.

  19. Spent fuel storage choices: What public opinion polls tell us

    International Nuclear Information System (INIS)

    Bisconti, A.S.

    1995-01-01

    The crux of the issue of spent nuclear fuel for much of the American public is that taking car of our waste now instead of leaving it for future generations is the safe and environmentally responsible think to do. This article summarizes a number of public opinion surveys. Although it is important to recognize that most people are not familiar with specifics, much of the American public has a strong opinions about the fundamental guiding principles for safely managing radioactive waste. First there is clear agreement that we need action. Second, safety means taking the waste to a permanent disposal facility instead of leaving it in many different locations. Third, most of the public would like to keep nuclear energy as a supply option. Fourth, the majority of the public agreed with the statement that the availability of nuclear energy as an option for future energy supply depends on building a national waste storage or disposal facility

  20. Information Spreadsheet for Engines and Vehicles Compliance Information System (EV-CIS) User Registration

    Science.gov (United States)

    In this spreadsheet, user(s) provide their company’s manufacturer code, user contact information for EV-CIS, and user roles. This spreadsheet is used for the Company Authorizing Official (CAO), CROMERR Signer, and EV-CIS Submitters.

  1. Opinion evolution in different social acquaintance networks

    Science.gov (United States)

    Chen, Xi; Zhang, Xiao; Wu, Zhan; Wang, Hongwei; Wang, Guohua; Li, Wei

    2017-11-01

    Social acquaintance networks influenced by social culture and social policy have a great impact on public opinion evolution in daily life. Based on the differences between socio-culture and social policy, three different social acquaintance networks (kinship-priority acquaintance network, independence-priority acquaintance network, and hybrid acquaintance network) incorporating heredity proportion ph and variation proportion pv are proposed in this paper. Numerical experiments are conducted to investigate network topology and different phenomena during opinion evolution, using the Deffuant model. We found that in kinship-priority acquaintance networks, similar to the Chinese traditional acquaintance networks, opinions always achieve fragmentation, resulting in the formation of multiple large clusters and many small clusters due to the fact that individuals believe more in their relatives and live in a relatively closed environment. In independence-priority acquaintance networks, similar to Western acquaintance networks, the results are similar to those in the kinship-priority acquaintance network. In hybrid acquaintance networks, similar to the Chinese modern acquaintance networks, only a few clusters are formed indicating that in modern China, opinions are more likely to reach consensus on a large scale. These results are similar to the opinion evolution phenomena in modern society, proving the rationality and applicability of network models combined with social culture and policy. We also found a threshold curve pv+2 ph=2.05 in the results for the final opinion clusters and evolution time. Above the threshold curve, opinions could easily reach consensus. Based on the above experimental results, a culture-policy-driven mechanism for the opinion dynamic is worth promoting in this paper, that is, opinion dynamics can be driven by different social cultures and policies through the influence of heredity and variation in interpersonal relationship networks. This

  2. Medical opinions, beliefs and prescription of orthopaedic footwear: A survey of Dutch orthopaedists and rehabilitation practitioners.

    NARCIS (Netherlands)

    Boer, Hendrik; Seydel, E.R.

    1998-01-01

    Objectives: To get insight into medical opinions about the use of orthopaedic footwear and the medical and social factors related to the prescription of orthopaedic footwear by orthopaedists and rehabilitation practitioners. Methods: In this study 85 orthopaedists and 96 rehabilitation practitioners

  3. The synthesis and preliminary pharmacological evaluation of the racemic cis and trans 3-alkylfentanyl analogues

    Directory of Open Access Journals (Sweden)

    LJ. DOSEN-MICOVIC

    2004-07-01

    Full Text Available A general, five step method for the synthesis of 3-alkylfentanyl analogues (i.e., cis and trans 3-alkyl-4-anilidopiperidines 6.1–6.6 has been developed. The starting N-phenethyl-4-piperidone 1 was first converted into the cyclohexylimine derivative 2, a-deprotonated with butyllithium and the resulting imine anion efficiently monoalkylated with primary and secondary alkyl halides. After mild acid hydrolysis, the obtained 3-alkyl-4-piperidones 3.1–3.6 were isolated in good yields (79–85 %, then condensed with aniline to form imines 4.1–4.6. Subsequent reduction of the imines (LiAlH4/THF yielded cis/trans mixtures of 3-alkyl-4-anilinopiperidines 5.1–5.6. Quantitative separation of the diastereoisomers by column chromatography of Al2O3 gave pure cis 5.1–5.6 (29–51 % yield and trans 5.1–5.6 (19–27 % yield, with the cis/trans ratio in the range 7/3–6/4. The synthesis was concluded by N-acylation of the purified 5.1–5.6, with propionyl chloride, to afford cis and trans 3-alkyl-4-anilidopiperidines 6.1–6.6 (~95 % yield, as monooxalate salts. No enatioseparation was attempted at any stage. The relative cis/trans stereochemistry was provisionally assigned from the 1H-NMR spectra. Of the twelve synthesized 3-alkylfentanyls, ten compounds (two known and eight novel derivatives, all as the monooxalate salts were preliminarily tested as analgesics in rats, comparing the potency to fentanyl. Except for the known (±-cis-3-Me fentanyl 6.1cis, (8 × fentanyl, and the novel (±-cis-3-Et fentanyl 6.2cis, (1.5 × fentanyl, all of the others were less active than fentanyl or inactive. Some tentative conclusions on the structure-activity relationship (SAR in this series of derivatives have been made.

  4. Identification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT)

    Science.gov (United States)

    Kaylor, Joanna J.; Cook, Jeremy D.; Makshanoff, Jacob; Bischoff, Nicholas; Yong, Jennifer; Travis, Gabriel H.

    2014-01-01

    Absorption of a photon by a rhodopsin or cone-opsin pigment isomerizes its 11-cis-retinaldehyde (11-cis-RAL) chromophore to all-trans-retinaldehyde (all-trans-RAL), which dissociates after a brief period of activation. Light sensitivity is restored to the resulting apo-opsin when it recombines with another 11-cis-RAL. Conversion of all-trans-RAL to 11-cis-RAL is carried out by an enzyme pathway called the visual cycle in cells of the retinal pigment epithelium. A second visual cycle is present in Müller cells of the retina. The retinol isomerase for this noncanonical pathway is dihydroceramide desaturase (DES1), which catalyzes equilibrium isomerization of retinol. Because 11-cis-retinol (11-cis-ROL) constitutes only a small fraction of total retinols in an equilibrium mixture, a subsequent step involving selective removal of 11-cis-ROL is required to drive synthesis of 11-cis-retinoids for production of visual chromophore. Selective esterification of 11-cis-ROL is one possibility. Crude homogenates of chicken retinas rapidly convert all-trans-ROL to 11-cis-retinyl esters (11-cis-REs) with minimal formation of other retinyl-ester isomers. This enzymatic activity implies the existence of an 11-cis-specific retinyl-ester synthase in Müller cells. Here, we evaluated multifunctional O-acyltransferase (MFAT) as a candidate for this 11-cis-RE-synthase. MFAT exhibited much higher catalytic efficiency as a synthase of 11-cis-REs versus other retinyl-ester isomers. Further, we show that MFAT is expressed in Müller cells. Finally, homogenates of cells coexpressing DES1 and MFAT catalyzed the conversion of all-trans-ROL to 11-cis-RP, similar to what we observed with chicken-retina homogenates. MFAT is therefore an excellent candidate for the retinyl-ester synthase that cooperates with DES1 to drive synthesis of 11-cis-retinoids by mass action. PMID:24799687

  5. Opinion Change: Information or Partisanship?

    DEFF Research Database (Denmark)

    Justesen, Mogens K.; Klemmensen, Robert; Leavitt, Thomas

    Currently two paradigms seek to explain how voters change their opinion when they are confronted with new information. One school argues that voters are bayesian updaters who rationally change their opinion. Another school argues that voters are inherently biased in their evaluation of new...... information. According to this line of thought voters are more likely to accept information that con_rms their opinion compared to information that contradict their point of view. Using a quasi experiment we investigate the extent to which voters rely on bayesian updating or on motivated reasoning when...

  6. Detection of trans-cis flips and peptide-plane flips in protein structures

    NARCIS (Netherlands)

    Touw, W.G.; Joosten, R.P.; Vriend, G.

    2015-01-01

    A coordinate-based method is presented to detect peptide bonds that need correction either by a peptide-plane flip or by a trans-cis inversion of the peptide bond. When applied to the whole Protein Data Bank, the method predicts 4617 trans-cis flips and many thousands of hitherto unknown

  7. PAA, WSH, and CIS Overview Self-Study #47656

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, Rachel Anne [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-14

    This course presents an overview of the Department of Energy’s (DOE’s) regulatory requirements relevant to the Price-Anderson Amendments Act (PAAA, also referred to as nuclear safety), worker safety and health (WSH), and classified information security (CIS) that are enforceable under the DOE enforcement program; describes the DOE enforcement process; and provides an overview of Los Alamos National Laboratory’s (LANL’s) internal compliance program relative to these DOE regulatory requirements. The LANL PAAA Program is responsible for maintaining LANL’s internal compliance program, which ensures the prompt identification, screening, and reporting of noncompliances to DOE regulatory requirements pertaining to nuclear safety, WSH, and CIS to build the strongest mitigation position for the Laboratory with respect to civil or other penalties.

  8. Opinion Summarizationof CustomerComments

    Science.gov (United States)

    Fan, Miao; Wu, Guoshi

    Web 2.0 technologies have enabled more and more customers to freely comment on different kinds of entities, such as sellers, products and services. The large scale of information poses the need and challenge of automatic summarization. In many cases, each of the user-generated short comments implies the opinions which rate the target entity. In this paper, we aim to mine and to summarize all the customer comments of a product. The algorithm proposed in this researchis more reliable on opinion identification because it is unsupervised and the accuracy of the result improves as the number of comments increases. Our research is performed in four steps: (1) mining the frequent aspects of a product that have been commented on by customers; (2) mining the infrequent aspects of a product which have been commented by customers (3) identifying opinion words in each comment and deciding whether each opinion word is positive, negative or neutral; (4) summarizing the comments. This paper proposes several novel techniques to perform these tasks. Our experimental results using comments of a number of products sold online demonstrate the effectiveness of the techniques.

  9. The IRSN 2012 barometer. The opinion on risks and security of the French population. Global results

    International Nuclear Information System (INIS)

    El Jammal, Marie-Helene; Rollinger, Francois; Mur, Emmanuelle

    2012-01-01

    This report presents and comments the results of a survey during which a sample of the French population has been questioned on their current concerns (what is the most concerning issue in the present society and in the environment, science within concerns), on their opinion on scientific expertise (who should control a risky installation, the role and image of experts, the access to expertise files, the perception of pluralist structures), on their opinion on 33 risk situations (risks to which French people feel exposed, confidence in authorities to protect them, truth of information on hazards, hierarchy of the 33 situations), on their opinion on the nuclear activity and industry (the nuclear risk, the credibility and expertise of interveners), and on the Fukushima accident (perception of the accident, quality of information, expectations on the assessment of nuclear power stations)

  10. Opinions in Denmark on the causes of peptic ulcer disease. A survey among Danish physicians and patients

    DEFF Research Database (Denmark)

    Christensen, A H; Gjørup, T; Andersen, I B

    1994-01-01

    stated more causes than did their male colleagues (p stress, were contributory causes of peptic ulcer disease, whereas only around 40% believed that coffee/tea, alcohol, smoking, side effects...... of medicine, and working conditions played a causal role. Around 95% of the physicians indicated that medical drugs and smoking were contributory causes of peptic ulcer disease, and around 80% that alcohol and psychologic factors were so. Only 30-40% of the physicians believed that coffee/tea, food habits......, infection, and working conditions could play a causal role in ulcer disease. It is concluded that the opinion on causal agents in peptic ulcer disease differ considerably among both patients and physicians. Opinions on causes of diseases may influence the way we treat and advise our patients, and attempts...

  11. Victimisation surveys: What are they good for?

    Directory of Open Access Journals (Sweden)

    Aromaa Kauko

    2012-01-01

    Full Text Available The author analyzes the usefulness of victimization surveys. The paper is focused of surveys in which nationally representative population samples are surveyed for their personal victimisation experiences, and their attitudes and opinions of issues related to crime and crime control. The author points out the benefits of using victimization surveys, but also explains why most countries have failed to make systematic use of this instrument.

  12. The results of opinion tracking in the UK

    International Nuclear Information System (INIS)

    Gittus, J.; Margerison, T.

    1991-01-01

    The British Nuclear Forum, or more accurately its predecessor, the Nuclear Electricity Information Group, undertook its first public attitudes survey in 1986 during the weekend following the Chernobyl accident. The original idea was to obtain guidance on the public's attitude to the relative credibility of the different authorities who might be offering information and advice. But the opportunity was also taken to measure the changing attitudes to nuclear energy and this proved to be the more rewarding part of the exercise. The most important question asked was 'Are you in favour or not of Britain producing electricity by means of nuclear power stations? The results of the surveys show there is a difference in the attitudes of men and women and between socio-economic class groups. The survey was continued at monthly intervals over the year following Chernobyl. Since then public attitudes have been surveyed at three monthly intervals with some changes in the questions and sampling procedure. The results of this monitoring are shown. Specific events, such as the issuing of the Gardner report suggesting a link between a father's exposure to radiation and the subsequent susceptibility of his children to leukaemia, are shown to influence public opinion. (UK)

  13. Selecting and training opinion leaders and best practice collaborators:Experience from the Canadian Chiropractic Guideline Initiative

    OpenAIRE

    Bussières, André E.; Maiers, Michele; Grondin, Diane; Brockhusen, Simon

    2017-01-01

    Objectives: To describe the process for selecting and training chiropractic opinion leaders (OLs) and best practice collaborators (BPCs) to increase the uptake of best practice. Methods: In Phase 1, OLs were identified using a cross-sectional survey among Canadian chiropractic stakeholders. A 10-member committee ranked nominees. Top-ranked nominees were invited to a training workshop. In Phase 2, a national e-survey was administered to 7200 Canadian chiropractors to identify additional OLs an...

  14. New probabilistic risk assessment of ethylhexyl methoxycinnamate: Comparing the genotoxic effects of trans- and cis-EHMC.

    Science.gov (United States)

    Nečasová, Anežka; Bányiová, Katarína; Literák, Jaromír; Čupr, Pavel

    2017-02-01

    Ethylhexyl methoxycinnamate (EHMC) is a widely used UV filter present in a large number of personal care products (PCPs). Under normal conditions, EHMC occurs in a mixture of two isomers: trans-EHMC and cis-EHMC in a ratio of 99:1. When exposed to sunlight, the trans isomer is transformed to the less stable cis isomer and the efficiency of the UV filter is reduced. To date, the toxicological effects of the cis-EHMC isomer remain largely unknown. We developed a completely new method for preparing cis-EHMC. An EHMC technical mixture was irradiated using a UV lamp and 98% pure cis-EHMC was isolated from the irradiated solution using column chromatography. The genotoxic effects of the isolated cis-EHMC isomer and the nonirradiated trans-EHMC were subsequently measured using two bioassays (SOS chromotest and UmuC test). In the case of trans-EHMC, significant genotoxicity was observed using both bioassays at the highest concentrations (0.5 - 4 mg mL -1 ). In the case of cis-EHMC, significant genotoxicity was only detected using the UmuC test at concentrations of 0.25 - 1 mg mL -1 . Based on these results, the NOEC was calculated for both cis- and trans-EHMC, 0.038 and 0.064 mg mL -1 , respectively. Risk assessment of dermal, oral and inhalation exposure to PCPs containing EHMC was carried out for a female population using probabilistic simulation and by using Quantitative in vitro to in vivo extrapolation (QIVIVE). The risk of cis-EHMC was found to be ∼1.7 times greater than trans-EHMC. In the case of cis-EHMC, a hazard index of 1 was exceeded in the 92nd percentile. Based on the observed differences between the isomers, EHMC application in PCPs requires detailed reassessment. Further exploration of the toxicological effects and properties of cis-EHMC is needed in order to correctly predict risks posed to humans and the environment. © 2016 Wiley Periodicals, Inc. Environ Toxicol 32: 569-580, 2017. © 2016 Wiley Periodicals, Inc.

  15. People's opinion of climate policy. Popular support for climate policy alternatives in Norway

    International Nuclear Information System (INIS)

    Marino, Sjoevaag Marit; Bjoerge, Nils Erik; Ericson, Torgeir; Garnaasjordet, Per Arild; Karlsen, Haakon T.; Randers; Joergen; Rees, Daniel

    2012-01-01

    How can we evaluate whether national climate policies are sufficient? Which moral principles should be the basis of our policy efforts? The answers to these questions are central to the development of any climate policy framework, but not always made explicit in daily political discourse. In this article we seek to redress this imbalance through a survey of popular opinion in Norway.(Author)

  16. School Library Policy and Legal Opinions of Texas Public School Principals and Certified Librarians

    Directory of Open Access Journals (Sweden)

    Andrew Shupala

    2006-09-01

    Full Text Available This study involved a survey of the attitudes of Texas public school principals and certified librarians, perceptions andexperiences with regard to school library policy for media selection, and procedures for responding to complaints againstlibrary media. Analysis of the data included a methodology of mixed-methods explanatory design. Selection of the principalsand certified librarians was proportionate and stratified according to the state's 20 Education Service Centerregions. Of the 1,036 independent school districts that employed the state population of 10,014 principals and certifiedlibrarians, 275 independent school districts (26.5 percent allowed participation in the survey. Although random samplingof the state population had not been possible, the demographic and employment characteristics of the study samplewere comparable to those of the state population. Two key findings were (a that the legal opinions of principals andcertified librarians were useful predictors of their opinions of library media selection policy and complaint proceduresand (b that the principals' appreciation of selection policy and complaint procedures sometimes differed from the librarians'because of the principals' different legal perspective of library selection policy and complaint procedures.

  17. A Self-Categorization Explanation for Opinion Consensus Perceptions

    Science.gov (United States)

    Zhang, Jinguang; Reid, Scott A.

    2013-01-01

    The public expression of opinions (and related communicative activities) hinges upon the perception of opinion consensus. Current explanations for opinion consensus perceptions typically focus on egocentric and other biases, rather than functional cognitions. Using self-categorization theory we showed that opinion consensus perceptions flow from…

  18. A CIS (Clinical Information System) Quality Evaluation Tool for Nursing Care Services

    Science.gov (United States)

    Lee, Seon Ah

    2010-01-01

    The purpose of this study was to develop a tool to evaluate the quality of a clinical information system (CIS) conceived by nurses and conduct a pilot test with the developed tool as an initial assessment. CIS quality is required for successful implementation in information technology (IT) environments. The study started with the realization that…

  19. Online and Social Media Data As an Imperfect Continuous Panel Survey.

    Science.gov (United States)

    Diaz, Fernando; Gamon, Michael; Hofman, Jake M; Kıcıman, Emre; Rothschild, David

    2016-01-01

    There is a large body of research on utilizing online activity as a survey of political opinion to predict real world election outcomes. There is considerably less work, however, on using this data to understand topic-specific interest and opinion amongst the general population and specific demographic subgroups, as currently measured by relatively expensive surveys. Here we investigate this possibility by studying a full census of all Twitter activity during the 2012 election cycle along with the comprehensive search history of a large panel of Internet users during the same period, highlighting the challenges in interpreting online and social media activity as the results of a survey. As noted in existing work, the online population is a non-representative sample of the offline world (e.g., the U.S. voting population). We extend this work to show how demographic skew and user participation is non-stationary and difficult to predict over time. In addition, the nature of user contributions varies substantially around important events. Furthermore, we note subtle problems in mapping what people are sharing or consuming online to specific sentiment or opinion measures around a particular topic. We provide a framework, built around considering this data as an imperfect continuous panel survey, for addressing these issues so that meaningful insight about public interest and opinion can be reliably extracted from online and social media data.

  20. Anisotropic opinion dynamics

    Science.gov (United States)

    Neirotti, Juan

    2016-07-01

    We consider the process of opinion formation in a society of interacting agents, where there is a set B of socially accepted rules. In this scenario, we observed that agents, represented by simple feed-forward, adaptive neural networks, may have a conservative attitude (mostly in agreement with B ) or liberal attitude (mostly in agreement with neighboring agents) depending on how much their opinions are influenced by their peers. The topology of the network representing the interaction of the society's members is determined by a graph, where the agents' properties are defined over the vertexes and the interagent interactions are defined over the bonds. The adaptability of the agents allows us to model the formation of opinions as an online learning process, where agents learn continuously as new information becomes available to the whole society (online learning). Through the application of statistical mechanics techniques we deduced a set of differential equations describing the dynamics of the system. We observed that by slowly varying the average peer influence in such a way that the agents attitude changes from conservative to liberal and back, the average social opinion develops a hysteresis cycle. Such hysteretic behavior disappears when the variance of the social influence distribution is large enough. In all the cases studied, the change from conservative to liberal behavior is characterized by the emergence of conservative clusters, i.e., a closed knitted set of society members that follow a leader who agrees with the social status quo when the rule B is challenged.

  1. Investment in the CEE/CIS region

    International Nuclear Information System (INIS)

    Lemierre, J.

    2002-01-01

    The energy investments in the Central and Eastern European region and the Commonwealth of Independent States (CIS) region are discussed in this Keynote Address. The message is addressed to regulators and governments. The restructuring of old industries to save energy is highlighted. The regulatory system must undergo a substantial reform. Another message is placed for investors in the energy field. (R.P.)

  2. Opinion evolution in different social acquaintance networks.

    Science.gov (United States)

    Chen, Xi; Zhang, Xiao; Wu, Zhan; Wang, Hongwei; Wang, Guohua; Li, Wei

    2017-11-01

    Social acquaintance networks influenced by social culture and social policy have a great impact on public opinion evolution in daily life. Based on the differences between socio-culture and social policy, three different social acquaintance networks (kinship-priority acquaintance network, independence-priority acquaintance network, and hybrid acquaintance network) incorporating heredity proportion p h and variation proportion p v are proposed in this paper. Numerical experiments are conducted to investigate network topology and different phenomena during opinion evolution, using the Deffuant model. We found that in kinship-priority acquaintance networks, similar to the Chinese traditional acquaintance networks, opinions always achieve fragmentation, resulting in the formation of multiple large clusters and many small clusters due to the fact that individuals believe more in their relatives and live in a relatively closed environment. In independence-priority acquaintance networks, similar to Western acquaintance networks, the results are similar to those in the kinship-priority acquaintance network. In hybrid acquaintance networks, similar to the Chinese modern acquaintance networks, only a few clusters are formed indicating that in modern China, opinions are more likely to reach consensus on a large scale. These results are similar to the opinion evolution phenomena in modern society, proving the rationality and applicability of network models combined with social culture and policy. We also found a threshold curve p v +2p h =2.05 in the results for the final opinion clusters and evolution time. Above the threshold curve, opinions could easily reach consensus. Based on the above experimental results, a culture-policy-driven mechanism for the opinion dynamic is worth promoting in this paper, that is, opinion dynamics can be driven by different social cultures and policies through the influence of heredity and variation in interpersonal relationship networks. This

  3. Selecting and training opinion leaders and best practice collaborators

    DEFF Research Database (Denmark)

    Bussières, André E.; Maiers, Michele; Grondin, Diane

    2017-01-01

    Objectives: To describe the process for selecting and training chiropractic opinion leaders (OLs) and best practice collaborators (BPCs) to increase the uptake of best practice. Methods: In Phase 1, OLs were identified using a cross-sectional survey among Canadian chiropractic stakeholders. A 10......-member committee ranked nominees. Top-ranked nominees were invited to a training workshop. In Phase 2, a national e-survey was administered to 7200 Canadian chiropractors to identify additional OLs and BPCs. Recommended names were screened by OLs and final selection made by consensus. Webinars were...... utilized to train BPCs to engage peers in best practices, and facilitate guideline dissemination. Results: In Phase 1, 21 OLs were selected from 80 nominees. Sixteen attended a training workshop. In Phase 2, 486 chiropractors recommended 1126 potential BPCs, of which 133 were invited to participate and 112...

  4. Situation Concerning Public Information about and Involvement in the Decision-Making Processes in the Nuclear Sector. Public Opinion Review

    International Nuclear Information System (INIS)

    Prades, A.; Sala, R.; Lopez, M.

    2006-01-01

    This report summarizes the CIEMAT's contribution to the study S ituation concerning Public Information about and Involvement in the Decision-Making Processes in the Nuclear Sector , contract number TREN/ 04/NUC/ S07.39556 between the European Commission and Mutadis Consultants. The research was composed by Mutadis Consultants and CEPN (Nuclear Protection Evaluation Centre) (France), University of Aberdeen (UK) and CIEMAT (Spain). The objective of the project was to build a detailed overview of the EU situation regarding information and participation practices in the nuclear domain, provide an elaborated assessment, and to produce reporting and recommendations in the field. CIEMAT contribution' focused on the review of public opinion polis. Thus, Eurobarometers Standard Surveys (EBs) were analysed to report about the European citizens' public opinion regarding public Information and participation in the nuclear field. Additionally, the International Social Survey Program (ISSP), and some additional national polis were analysed. In terms of the EU public opinion, the follow up of the public information and participation domains receiving as much attention as necessary. Extremely few questions dealing with the subject were identified in the Eurobarometers, the national polis and the ISSP (International Social Survey Program) surveys reviewed in this study. An unambiguous illustration of this lack of attention is the fact that no questions dealing with public participation issues emerged in the n uclear EBs u ntil 1998. Even though, Eurobarometers (EBs) still provide an invaluable source of information on the topics we are interested on at the EU allowing longitudinal descriptions (trend analysis) of some key issues in our area of interest. (Author) 11 refs

  5. School nurses' knowledge, attitudes, perceptions of role as opinion leader, and professional practice regarding human papillomavirus vaccine for youth.

    Science.gov (United States)

    Rosen, Brittany L; Goodson, Patricia; Thompson, Bruce; Wilson, Kelly L

    2015-02-01

    Because human papillomavirus (HPV) vaccine rates remain low, we evaluated US school nurses' knowledge, attitudes, perceptions of their role as opinion leaders, and professional practice regarding HPV vaccine, and assessed whether knowledge, attitudes, and perceptions of being an opinion leader influenced their professional practice regarding the HPV vaccine. We used a cross-sectional design by recruiting members from the National Association of School Nurses. All participants (N = 505) were e-mailed a survey designed for this study. Structural equation modeling (SEM) tested direct and indirect effects. Overall, school nurses had knowledge about HPV and the vaccine, and positive attitudes toward the vaccine. They had less-than-enthusiastic perceptions of their role as opinion leaders regarding the vaccine and implemented few activities related to providing vaccine information. The model revealed a good fit (χ(2)=20.238 [df=8, prole as opinion leaders. © 2015, American School Health Association.

  6. How Public Opinion is Formed

    Science.gov (United States)

    Block, Edward M.

    1977-01-01

    Investigates the evolution of the definition of public relations by examining cultural and personal determinants of public opinion. Outlines functions of communicators and opinionmakers in forming and influencing public opinion. Available from: Public Relations Review, Ray Hiebert, Dean, College of Journalism, University of Maryland, College Park,…

  7. Public opinion survey 'Nuclear energy - the present and the future'

    International Nuclear Information System (INIS)

    Prah, M.; Jurkovic, I.-A.; Matanic, R.; Lebegner, J.

    2001-01-01

    As a part of Croatian Nuclear Society Young Generation Network efforts in improving relations with the general public, a survey on nuclear energy issues among a student population (18-22 years old) has been planned. The survey, although somewhat modified, is based on a similar one that has been conducted at high schools as a part of organized educational program by the Museum of Technical Sciences and Hrvatska Elektroprivreda. (authors)

  8. Public opinion survey 'Nuclear energy - the present and the future'

    International Nuclear Information System (INIS)

    Jurkovic, I.-A.; Jecmenica, R.; Prah, M.; Matanic, R.; Lebegner, J.

    2000-01-01

    As a part of Croatian Nuclear Society Young Generation Network efforts in improving relations with the general public, a survey on nuclear energy issues among a student population (18-22 years old) has been planned. The survey, although somewhat modified, is based on a similar one that has been conducted at high schools as a part of organized educational program by the Museum of Technical Sciences and Hrvatska Elektroprivreda. (author)

  9. First start toward nuclear disarmament: CIS openness and compliance. Research report, August 1991-April 1992

    Energy Technology Data Exchange (ETDEWEB)

    Casteel, B.

    1992-04-01

    In the last six months we have seen significant changes in the Soviet Union which have radically altered that way we have conducted business. Now, it is no longer the Soviet Union, but the Commonwealth of Independent States (CIS). We are now making wholesale unilateral cuts in our defense structure as the CIS is viewed as our friend and no longer the Evil Empire. We are supplying the CIS with food, loan credits, and even offering assistance to help them destroy nuclear weapons. Even though the world has changed, the CIS remains the only country on the face of the earth capable of destroying the United States in a nuclear holocaust.

  10. Determinants of favourable opinions about euthanasia in a sample of French physicians.

    Science.gov (United States)

    Dany, Lionel; Baumstarck, Karine; Dudoit, Eric; Duffaud, Florence; Auquier, Pascal; Salas, Sébastien

    2015-11-05

    The question whether euthanasia should be legalised has led to substantial public debate in France. The objective of this study in a sample of French physicians was to establish the potential determinants of a favourable opinion about euthanasia in general and when faced with a specific situation as embodied in the Humbert affair. The study was a cross-sectional survey investigating two different samples of medical doctors: (1) those specialised in palliative care and affiliated to the French Society for Patient Accompaniment and Palliative Care; (2) medical interns (medical doctors in training course) in a French medical university (Marseille). A questionnaire was sent (email) to each voluntary participant including sociodemographics, professional status, mention of believing in God, and opinion about euthanasia (the question was designed to assess the general opinion about euthanasia and the opinion about a specific case, the Vincent Humbert' case (a man who was rendered quadriplegic, blind, and mute after an accident and has requested euthanasia). A total of 413 physicians participated in the research (participation rate: 48.5%). Less than half of the population were favourable to euthanasia in general and almost two-thirds of the population were favourable to Vincent Humbert's request for euthanasia. Based on the multivariate analysis, individuals believing in God and being a medical intern were significant independent factors linked to having a favourable opinion about euthanasia in general and about the Vincent Humbert's request. There is still no study in France on the development of opinion about euthanasia and its impact. The issue goes beyond the strictly professional sphere and involves broader socio-political stakes. These stakes do not necessarily take into account medical practices and experiences or the desires of end-of-life patients. The professional upheaval that the future French legal framework will doubtlessly trigger will require further

  11. A survey on the regional characteristics of public's nuclear recognition

    International Nuclear Information System (INIS)

    Ohnishi, Teruaki; Okada, Osami; Tsujimoto, Tadashi

    2001-03-01

    Public opinion surveys were carried out to clarify the difference of nuclear perception of the public dwelling near the region of nuclear power station and the public in the urban region. A simulation model using the data obtained up to this time was developed to make clear the regional dependence of the public's perception of nuclear energy, and the secular variation of public opinion for nuclear energy corresponding to the two regions cited above was numerically studied by this model. In our surveys, a convenient method using the Internet, together with the ordinary mailing method were adopted to compare the two types of data thus obtained by the different methods and to study the feasibility of the Internet method. The questionnaires in these surveys are, for instance, the extent of the public recognition of energy in general and nuclear energy, the recognition of inhabitant's poll, and the public's attitude to the mass media, with the objective region of Reinan in Fukui prefecture and the urban region in Kinki district for the case of mailing method, and the whole region in our country for the Internet method. By the simulation model of multi-particle type with the input data obtained by our surveys, the behavior of secular variation of nuclear opinion and the effect of PA activity were numerically studied. The present status of public perception and recognition of nuclear energy became clear as a result of our surveys. It was found that the Internet is a quite useful mean to carry out the opinion survey with a low cost in a short time, and that the multi-particle model can be a useful tool to numerically evaluate the effect of PA activity. (author)

  12. SWIMMING CLASSES IN JUNIOR HIGH SCHOOL STUDENTS’ OPINION

    Directory of Open Access Journals (Sweden)

    Grzegorz Bielec

    2013-02-01

    Full Text Available The role of modern physical education is not only to develop motor abilities of the students, but most of all prevent them from epidemic youth diseases such as obesity or postural defects. Positive attitudes to swimming as a long-life physical activity, instilled in adolescence should be beneficial in adult life. The group of 130 boys and 116 girls of 7th grade junior high school (mean age 14.6 was asked in the survey to present their opinion of obligatory swimming lessons at school. Students of both sexes claimed that they liked swimming classes because they could improve their swimming skills (59% of answers and because of health-related character of water exercises (38%. 33% of students regarded swimming lessons as boring and monotonous, and 25% of them complained about poor pool conditions like chlorine smell, crowded lanes, too low temperature. Majority of the surveyed students saw practical role of swimming in saving others life.

  13. Causes of delays on Construction Projects in Kuwait according to opinion of engineers working in Kuwait

    OpenAIRE

    Naser S. Almutairi

    2016-01-01

    This paper presents an investigation into analysis of the causes of delays on Construction Projects in Kuwait according to opinion of engineers working in Kuwait. This is achieved through identification of the major causes of delays in the construction industry as reported in literature and using a questionnaire survey to collect the views of the various key players in the Kuwaiti construction industry. The data is analyzed and the views of the groups surveyed discussed and the relative impor...

  14. Survey Research: Methods, Issues and the Future

    Science.gov (United States)

    Brewer, Ernest W.; Torrisi-Steele, Geraldine; Wang, Victor C. X.

    2015-01-01

    Survey research is prevalent among many professional fields. Both cost effective and time efficient, this method of research is commonly used for the purposes of gaining insight into the attitudes, thoughts, and opinions of populations. Additionally, because there are several types of survey research designs and data collection instruments, the…

  15. Use of expert opinion for animal disease decisions: an example of foot-and-mouth disease status designation.

    Science.gov (United States)

    Garabed, R B; Perez, A M; Johnson, W O; Thurmond, M C

    2009-11-01

    When data representing a preferred measurement of risk cannot be obtained, as is often the case for global animal diseases, decisions that affect millions of people and their animals are typically made based on expert opinion. Expert opinion can be and has been used to address the critical lack of data existing for prevalence and incidence of many global diseases, including foot-and-mouth disease (FMD). However, when a conclusion based on expert opinion applies to a topic as sensitive as FMD, which has tremendous economic, political, and social implications, care should be taken to understand the accuracy of and differences in the opinion data. The differences in experts' opinions and the relative accuracy of an expert opinion elicitation for "diagnosing" country-level FMD presence were examined for the years 1997-2003 using Bayesian methods. A formal survey of eight international FMD experts revealed that individual experts had different opinions as to the probability of finding FMD in a country. However, a weighted average of the experts' responses was relatively accurate (91% sensitivity and 85% specificity) at identifying the FMD status of a country, compared to using a method that employed information available from World Organization for Animal Health (OIE). The most apparent disagreements between individual experts and available information were found for Indonesia, South Korea, and South America, and, in general, the experts seemed to believe that countries in South Asia were more likely to be positive than other countries that reported FMD cases to OIE. This study highlights new methodology that offers a standardized, quantitative, and systematic means by which expert opinion can be used and assessed.

  16. Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor

    Science.gov (United States)

    Walterscheid, Jeffrey P.; Nghiem, Dat X.; Kazimi, Nasser; Nutt, Leta K.; McConkey, David J.; Norval, Mary; Ullrich, Stephen E.

    2006-01-01

    Exposure to UV radiation induces skin cancer and suppresses the immune response. To induce immune suppression, the electromagnetic energy of UV radiation must be absorbed by an epidermal photoreceptor and converted into a biologically recognizable signal. Two photoreceptors have been recognized: DNA and trans-urocanic acid (UCA). Trans-UCA is normally found in the outermost layer of skin and isomerizes to the cis isomer upon exposure to UV radiation. Although UCA was identified as a UV photoreceptor years ago, and many have documented its ability to induce immune suppression, its exact mode of action remains elusive. Particularly vexing has been the identity of the molecular pathway by which cis-UCA mediates immune suppression. Here we provide evidence that cis-UCA binds to the serotonin [5-hydroxytryptamine (5-HT)] receptor with relatively high affinity (Kd = 4.6 nM). Anti-cis-UCA antibody precipitates radiolabeled 5-HT, and the binding is inhibited by excess 5-HT and/or excess cis-UCA. Similarly, anti-5-HT antibody precipitates radiolabeled cis-UCA, and the binding is inhibited by excess 5-HT or excess cis-UCA. Calcium mobilization was activated when a mouse fibroblast line, stably transfected with the human 5-HT2A receptor, was treated with cis-UCA. Cis-UCA-induced calcium mobilization was blocked with a selective 5-HT2A receptor antagonist. UV- and cis-UCA-induced immune suppression was blocked by antiserotonin antibodies or by treating the mice with 5-HT2A receptor antagonists. Our findings identify cis-UCA as a serotonin receptor ligand and indicate that the immunosuppressive effects of cis-UCA and UV radiation are mediated by activation of the 5-HT2A receptor. PMID:17085585

  17. 28 CFR 80.8 - Attorney General opinion.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Attorney General opinion. 80.8 Section 80.8 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) FOREIGN CORRUPT PRACTICES ACT OPINION PROCEDURE § 80.8 Attorney General opinion. The Attorney General or his designee shall, within 30 days after...

  18. Studies in Swedish Energy Opinion

    Energy Technology Data Exchange (ETDEWEB)

    Holmberg, Soeren; Hedberg, Per

    2012-07-01

    -length studies of Swedish mass attitudes toward nuclear power appeared already in the late 1970-ies. Since then all SNES surveys have included measurements of Swedish opinions on various energy issues. A special election study was done in 1980 covering the nuclear power referendum. Beginning in 1986, SNES's election year measurements were supplemented by annual studies done by the newly founded SOM Institute at Univ. of Gothenburg. These annual measurements were from the start designed and coordinated by the research project Energy Opinion in Sweden, originally financially supported by the now non-existent National Board for Spent Fuel, but since 1999 financed by The Swedish Energy Agency. The analyses in the chapters in this English language book compendium have all been done and published under the auspices of the research project Energy Opinion in Sweden. The time span is quite long, over twenty years. The writing in Chapter 1 appeared already in 1991, while the results in Chapters 7 and 8 are from 2011.

  19. school-based survey of adolescents' opinion on premarital sex

    African Journals Online (AJOL)

    PROF. BARTH EKWEME

    Method: A cross sectional descriptive survey design was used. ... a taboo between parents and children. The adolescents learned through the mass media and peers unguided. ... adolescents, males reported more permissive attitudes towards ...

  20. Detection of trans–cis flips and peptide-plane flips in protein structures

    Energy Technology Data Exchange (ETDEWEB)

    Touw, Wouter G., E-mail: wouter.touw@radboudumc.nl [Radboud University Medical Center, Geert Grooteplein-Zuid 26-28, 6525 GA Nijmegen (Netherlands); Joosten, Robbie P. [Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam (Netherlands); Vriend, Gert, E-mail: wouter.touw@radboudumc.nl [Radboud University Medical Center, Geert Grooteplein-Zuid 26-28, 6525 GA Nijmegen (Netherlands)

    2015-07-28

    A method is presented to detect peptide bonds that need either a trans–cis flip or a peptide-plane flip. A coordinate-based method is presented to detect peptide bonds that need correction either by a peptide-plane flip or by a trans–cis inversion of the peptide bond. When applied to the whole Protein Data Bank, the method predicts 4617 trans–cis flips and many thousands of hitherto unknown peptide-plane flips. A few examples are highlighted for which a correction of the peptide-plane geometry leads to a correction of the understanding of the structure–function relation. All data, including 1088 manually validated cases, are freely available and the method is available from a web server, a web-service interface and through WHAT-CHECK.

  1. Detection of trans–cis flips and peptide-plane flips in protein structures

    International Nuclear Information System (INIS)

    Touw, Wouter G.; Joosten, Robbie P.; Vriend, Gert

    2015-01-01

    A method is presented to detect peptide bonds that need either a trans–cis flip or a peptide-plane flip. A coordinate-based method is presented to detect peptide bonds that need correction either by a peptide-plane flip or by a trans–cis inversion of the peptide bond. When applied to the whole Protein Data Bank, the method predicts 4617 trans–cis flips and many thousands of hitherto unknown peptide-plane flips. A few examples are highlighted for which a correction of the peptide-plane geometry leads to a correction of the understanding of the structure–function relation. All data, including 1088 manually validated cases, are freely available and the method is available from a web server, a web-service interface and through WHAT-CHECK

  2. Identifying Opinion Leaders to Promote Behavior Change

    Science.gov (United States)

    Valente, Thomas W.; Pumpuang, Patchareeya

    2007-01-01

    This article reviews 10 techniques used to identify opinion leaders to promote behavior change. Opinion leaders can act as gatekeepers for interventions, help change social norms, and accelerate behavior change. Few studies document the manner in which opinion leaders are identified, recruited, and trained to promote health. The authors categorize…

  3. cis-Tetrachlorido-bis(indazole)osmium(iv) and its osmium(iii) analogues: paving the way towards the cis-isomer of the ruthenium anticancer drugs KP1019 and/or NKP1339

    KAUST Repository

    Bü chel, Gabriel E.; Kossatz, Susanne; Sadique, Ahmad; Rapta, Peter; Zalibera, Michal; Bucinsky, Lukas; Komorovsky, Stanislav; Telser, Joshua; Eppinger, Jö rg; Reiner, Thomas; Arion, Vladimir B.

    2017-01-01

    The relationship between cis-trans isomerism and anticancer activity has been mainly addressed for square-planar metal complexes, in particular, for platinum(II), e.g., cis- and trans-[PtCl2(NH3)(2)], and a number of related compounds, of which, however, only cis-counterparts are in clinical use today. For octahedral metal complexes, this effect of geometrical isomerism on anticancer activity has not been investigated systematically, mainly because the relevant isomers are still unavailable. An example of such an octahedral complex is trans-[RuCl4(Hind)(2)](-), which is in clinical trials now as its indazolium (KP1019) or sodium salt (NKP1339), but the corresponding cis-isomers remain inaccessible. We report the synthesis of Na[cis-(OsCl4)-Cl-III(kappa N2-1H-ind)(2)] . (Na[1]) suggesting a route to the cis-isomer of NKP1339. The procedure involves heating (H(2)ind)[(OsCl5)-Cl-IV(kappa N1-2H-ind)] in a high boiling point organic solvent resulting in an Anderson rearrangement with the formation of cis-[(OsCl4)-Cl-IV(kappa N2-1H-ind)(2)] ([1]) in high yield. The transformation is accompanied by an indazole coordination mode switch from kappa N1 to kappa N2 and stabilization of the 1H-indazole tautomer. Fully reversible spectroelectrochemical reduction of [1] in acetonitrile at 0.46 V vs. NHE is accompanied by a change in electronic absorption bands indicating the formation of cis-[(OsCl4)-Cl-III(kappa N2-1H-ind)(2)](-) ([1](-)). Chemical reduction of [1] in methanol with NaBH4 followed by addition of nBu(4)NCl afforded the osmium(III) complex nBu(4)N[cis-(OsCl4)-Cl-III(kappa N2-1H-ind)(2)] (nBu(4)N [1]). A metathesis reaction of nBu(4)N[1] with an ion exchange resin led to the isolation of the water-soluble salt Na[1]. The X-ray diffraction crystal structure of [1] . Me2CO was determined and compared with that of trans-[(OsCl4)-Cl-IV(kappa N2-1H-ind)(2)] . 2Me(2)SO (2 . 2Me(2)SO), also prepared in this work. EPR spectroscopy was performed on the Os-III complexes and

  4. cis-Tetrachlorido-bis(indazole)osmium(iv) and its osmium(iii) analogues: paving the way towards the cis-isomer of the ruthenium anticancer drugs KP1019 and/or NKP1339

    KAUST Repository

    Büchel, Gabriel E.

    2017-08-15

    The relationship between cis-trans isomerism and anticancer activity has been mainly addressed for square-planar metal complexes, in particular, for platinum(II), e.g., cis- and trans-[PtCl2(NH3)(2)], and a number of related compounds, of which, however, only cis-counterparts are in clinical use today. For octahedral metal complexes, this effect of geometrical isomerism on anticancer activity has not been investigated systematically, mainly because the relevant isomers are still unavailable. An example of such an octahedral complex is trans-[RuCl4(Hind)(2)](-), which is in clinical trials now as its indazolium (KP1019) or sodium salt (NKP1339), but the corresponding cis-isomers remain inaccessible. We report the synthesis of Na[cis-(OsCl4)-Cl-III(kappa N2-1H-ind)(2)] . (Na[1]) suggesting a route to the cis-isomer of NKP1339. The procedure involves heating (H(2)ind)[(OsCl5)-Cl-IV(kappa N1-2H-ind)] in a high boiling point organic solvent resulting in an Anderson rearrangement with the formation of cis-[(OsCl4)-Cl-IV(kappa N2-1H-ind)(2)] ([1]) in high yield. The transformation is accompanied by an indazole coordination mode switch from kappa N1 to kappa N2 and stabilization of the 1H-indazole tautomer. Fully reversible spectroelectrochemical reduction of [1] in acetonitrile at 0.46 V vs. NHE is accompanied by a change in electronic absorption bands indicating the formation of cis-[(OsCl4)-Cl-III(kappa N2-1H-ind)(2)](-) ([1](-)). Chemical reduction of [1] in methanol with NaBH4 followed by addition of nBu(4)NCl afforded the osmium(III) complex nBu(4)N[cis-(OsCl4)-Cl-III(kappa N2-1H-ind)(2)] (nBu(4)N [1]). A metathesis reaction of nBu(4)N[1] with an ion exchange resin led to the isolation of the water-soluble salt Na[1]. The X-ray diffraction crystal structure of [1] . Me2CO was determined and compared with that of trans-[(OsCl4)-Cl-IV(kappa N2-1H-ind)(2)] . 2Me(2)SO (2 . 2Me(2)SO), also prepared in this work. EPR spectroscopy was performed on the Os-III complexes and

  5. A study of the public opinion concerning nuclear power generation in the United States

    International Nuclear Information System (INIS)

    Oiso, Shinichi

    2008-01-01

    In this study, I surveyed the outcome of opinion poll about people's attitude toward nuclear power and analysed their awareness of nuclear power generation in the United States. As a result, it was found that percentage of the people who have positive attitude toward nuclear power has been over 60% since 1998. This result corresponds to the fact that people's preference is tending more toward nuclear power generation which is called the nuclear power Renaissance in the United States. Furthermore, analysis of the outcome of the opinion poll in power stations site region was also conducted and it was found that attitude of the people in the site region was more positive than that of average level in the United States. (author)

  6. cisTEM, user-friendly software for single-particle image processing

    Science.gov (United States)

    2018-01-01

    We have developed new open-source software called cisTEM (computational imaging system for transmission electron microscopy) for the processing of data for high-resolution electron cryo-microscopy and single-particle averaging. cisTEM features a graphical user interface that is used to submit jobs, monitor their progress, and display results. It implements a full processing pipeline including movie processing, image defocus determination, automatic particle picking, 2D classification, ab-initio 3D map generation from random parameters, 3D classification, and high-resolution refinement and reconstruction. Some of these steps implement newly-developed algorithms; others were adapted from previously published algorithms. The software is optimized to enable processing of typical datasets (2000 micrographs, 200 k – 300 k particles) on a high-end, CPU-based workstation in half a day or less, comparable to GPU-accelerated processing. Jobs can also be scheduled on large computer clusters using flexible run profiles that can be adapted for most computing environments. cisTEM is available for download from cistem.org. PMID:29513216

  7. cisTEM, user-friendly software for single-particle image processing.

    Science.gov (United States)

    Grant, Timothy; Rohou, Alexis; Grigorieff, Nikolaus

    2018-03-07

    We have developed new open-source software called cis TEM (computational imaging system for transmission electron microscopy) for the processing of data for high-resolution electron cryo-microscopy and single-particle averaging. cis TEM features a graphical user interface that is used to submit jobs, monitor their progress, and display results. It implements a full processing pipeline including movie processing, image defocus determination, automatic particle picking, 2D classification, ab-initio 3D map generation from random parameters, 3D classification, and high-resolution refinement and reconstruction. Some of these steps implement newly-developed algorithms; others were adapted from previously published algorithms. The software is optimized to enable processing of typical datasets (2000 micrographs, 200 k - 300 k particles) on a high-end, CPU-based workstation in half a day or less, comparable to GPU-accelerated processing. Jobs can also be scheduled on large computer clusters using flexible run profiles that can be adapted for most computing environments. cis TEM is available for download from cistem.org. © 2018, Grant et al.

  8. UK Public Opinion Review - Working Paper - An overview of public opinion polls since the Edward Snowden revelations in June 2013

    OpenAIRE

    Cable, Jonathan

    2015-01-01

    This document charts public opinion of the Edward Snowden leaks and associated issues\\ud since June 2013. This includes people’s opinions on surveillance, the intelligence services\\ud and personal privacy. Since the Snowden leaks there have been 38 opinion polls on these\\ud topics concerning public opinion in the UK and conducted by large polling organisations,\\ud such as YouGov, ComRes and Ipsos MORI among others.

  9. [First results of a German second opinion program show high patient satisfaction and large discrepancies between initial therapy recommendations and second opinion].

    Science.gov (United States)

    Weyerstraß, Jan; Prediger, Barbara; Neugebauer, Edmund; Pieper, Dawid

    2018-02-23

    Although legally anchored, there are no empirical results from German second opinion programs. In this study, various aspects within a population of a second opinion program are examined. In this study patients were analyzed who sought a second opinion in the period from August 2011 to December 2016. Differences in patient characteristics, differentiated by agreement of first and second opinion, were analyzed using multivariate logistic regression. Patients' satisfaction and quality of life were examined one, three and six months after obtaining the second opinion. In total, 1,414 patients sought a second opinion. Most frequent medical indications were the knee (38.7 %), the back (26.8 %), the hip (11.7 %), and the shoulder (10.2 %). Except for the indication (p=0.035), no patient characteristic had influence on the conformation of the second opinion. Approximately two out of three initial recommendations were not confirmed by the specialists. 89 % of the patients were satisfied or very satisfied with the second opinion and the service offered. The second opinion offers patients the opportunity to seek an additional independent medical opinion and thus provide support for decision making. Further research is needed to examine the reasons for the high discrepancies between the first and second opinions. Copyright © 2018. Published by Elsevier GmbH.

  10. Viscometric study of high-cis polybutadiene in toluene solution

    International Nuclear Information System (INIS)

    Mwllo, Ivana L.; Coutinho, Fernanda M.B.; Delpech, Marcia C.; Albino, Fernanda F.M.

    2006-01-01

    Viscometric measurements, in toluene solution at 30 deg C, were performed with high-cis polybutadiene synthesized by neodymium based catalyst. Six different equations were used to calculate intrinsic viscosities and viscosimetric constant values: Huggins, Kraemer, Martin and Schulz-Blaschke by graphic extrapolation, and Solomon-Ciuta, Deb-Chanterjee and again Schulz- Blaschke, through a single point determination. The molecular weight of the polymers was also determined applying Mark-Houwink-Sakurada equation using the values of intrinsic viscosity obtained by the six equations. The values of intrinsic viscosity and viscosity-average molecular weight obtained by the two methods were compared in order to verify the validity of the single point determination for high-cis polybutadiene. (author)

  11. [The residents of mental health services in 1994. Population characteristics and its opinions about graduation].

    Science.gov (United States)

    Agrest, M

    1995-09-01

    Departing from two surveys that took place during a Mental Health Meeting of the Health Residents from Buenos Aires, the main features and their opinions upon their education and work are analyzed. The results are discriminated by profession. Two problems are highlighted: one of them refers to the general insatisfaction of this group with their theoretical learning; the other, shows the exit of prepared human resources from public hospitals. The data suggest that, despite sharing most of their activities, psychologists and psychiatrists have significant different opinions about the clinic education they think are getting. Further research is suggested in order to have a deeper comprehension of what is going on in these training programs.

  12. Protection against the clastogenic effect of CIS-PLATINUM by WR-2721, ATP and Vitamin C

    International Nuclear Information System (INIS)

    Rupova, I.; Yagova, A.

    1993-01-01

    The mutagenic effect of antineoplastic drug Cis-Platinum has been assessed by the frequency of micronuclei in polychromatic erythrocytes (PE) in the mouse bone marrow at time intervals of 24, 48 and 73 h. The maximal clastogenic effect of 2 mg/kg of Cis-Platinum has been found at 24 h interval after treatment (3.6%). The protection against mutagenic activity of Cis-Platinum has been studied by pretreatment of the mice with the thiophosphate compound WR-2721, adenosine triphosphate (ATP) and Vitamin C alone or in combinations at the time of maximal response. The radioprotector WR-2721 exerts a high anti-mutagenic activity when applied prior to Cis-Platinum (2.2%; p 0.05). (author)

  13. Familiarity, opinions, experiences and knowledge about scalp cooling: a Dutch survey among breast cancer patients and oncological professionals

    Directory of Open Access Journals (Sweden)

    Mijke Peerbooms

    2015-01-01

    Full Text Available Objective: Scalp cooling (SC is applied to reduce chemotherapy-induced alopecia (CIA. The aim of this study was to investigate patients′ familiarity and opinions and oncological professionals′ attitude and knowledge about SC in the Netherlands. Methods: Ex breast cancer patients, nurses and medical oncologists (MDs from SC and non-SC hospitals filled out questionnaires. Results: The majority of MDs and nurses were satisfied with the results of SC, as were SC patients. Over 33% of MDs and nurses perceived their knowledge level insufficient to inform patients about effectiveness, which was over 43% for information about safety. MDs main reason to not apply SC was doubt about effectiveness and safety. Nurses generally offered SC to a minority of eligible patients. Patients were frequently unfamiliar with SC before diagnosis. Seventy percent of SC patients with insufficient results (20/52 reported to mind it very much. With expected success rates of 35% and 50%, respectively, 36% and 54% of patients would use SC again. Conclusion: Room for improvement has been shown for both patients′ familiarity and oncological professionals′ knowledge about SC. Sharing knowledge about results, safety and patients′ experiences will improve patient counseling and SC availability. The results of this survey led to the development of a national standard on CIA and SC.

  14. Applications of flow-networks to opinion-dynamics

    Science.gov (United States)

    Tupikina, Liubov; Kurths, Jürgen

    2015-04-01

    Networks were successfully applied to describe complex systems, such as brain, climate, processes in society. Recently a socio-physical problem of opinion-dynamics was studied using network techniques. We present the toy-model of opinion-formation based on the physical model of advection-diffusion. We consider spreading of the opinion on the fixed subject, assuming that opinion on society is binary: if person has opinion then the state of the node in the society-network equals 1, if the person doesn't have opinion state of the node equals 0. Opinion can be spread from one person to another if they know each other, or in the network-terminology, if the nodes are connected. We include into the system governed by advection-diffusion equation the external field to model such effects as for instance influence from media. The assumptions for our model can be formulated as the following: 1.the node-states are influenced by the network structure in such a way, that opinion can be spread only between adjacent nodes (the advective term of the opinion-dynamics), 2.the network evolution can have two scenarios: -network topology is not changing with time; -additional links can appear or disappear each time-step with fixed probability which requires adaptive networks properties. Considering these assumptions for our system we obtain the system of equations describing our model-dynamics which corresponds well to other socio-physics models, for instance, the model of the social cohesion and the famous voter-model. We investigate the behavior of the suggested model studying "waiting time" of the system, time to get to the stable state, stability of the model regimes for different values of model parameters and network topology.

  15. The role of 11-cis-retinyl esters in vertebrate cone vision.

    Science.gov (United States)

    Babino, Darwin; Perkins, Brian D; Kindermann, Aljoscha; Oberhauser, Vitus; von Lintig, Johannes

    2015-01-01

    A cycle of cis-to-trans isomerization of the chromophore is intrinsic to vertebrate vision where rod and cone photoreceptors mediate dim- and bright-light vision, respectively. Daylight illumination can greatly exceed the rate at which the photoproduct can be recycled back to the chromophore by the canonical visual cycle. Thus, an additional supply pathway(s) must exist to sustain cone-dependent vision. Two-photon microscopy revealed that the eyes of the zebrafish (Danio rerio) contain high levels of 11-cis-retinyl esters (11-REs) within the retinal pigment epithelium. HPLC analyses demonstrate that 11-REs are bleached by bright light and regenerated in the dark. Pharmacologic treatment with all-trans-retinylamine (Ret-NH2), a potent and specific inhibitor of the trans-to-cis reisomerization reaction of the canonical visual cycle, impeded the regeneration of 11-REs. Intervention with 11-cis-retinol restored the regeneration of 11-REs in the presence of all-trans-Ret-NH2. We used the XOPS:mCFP transgenic zebrafish line with a functional cone-only retina to directly demonstrate that this 11-RE cycle is critical to maintain vision under bright-light conditions. Thus, our analyses reveal that a dark-generated pool of 11-REs helps to supply photoreceptors with the chromophore under the varying light conditions present in natural environments. © FASEB.

  16. Public opinion about biofuels: The interplay between party identification and risk/benefit perception

    International Nuclear Information System (INIS)

    Fung, Timothy K.F.; Choi, Doo Hun; Scheufele, Dietram A.; Shaw, Bret R.

    2014-01-01

    Using an experiment embedded within a representative survey, this study examined the interactive effect of party identification and risk/benefit perception on public opinion about biofuels. Democrats tended to be more supportive of biofuels than Republicans. However, the effect of party identification on opinion about biofuels varied when individuals considered the risk/benefit of biofuels in different domains. Individuals who reported greater affiliation with the Democratic Party were likely to support funding biofuels research when primed with the economic risks or the social/ethical benefits of biofuels. For those who considered the social/ethical benefits of biofuels, more self-identified Democrats were likely to support biofuels production and use. However, more self-identified Democrats were less supportive of biofuels production and use when they considered the political risks of biofuels. Implications are discussed. - Highlights: • We examined public opinion about biofuels policies. • Effect of risk/benefit perception varied across respondents' party identification. • Democrats favored more research when considering economic risks or social benefits. • Democrats favored biofuels more when considering social benefits. • Democrats favored biofuels less when considering political risks

  17. Discrepancy and Disliking Do Not Induce Negative Opinion Shifts

    Science.gov (United States)

    Flache, Andreas; Mäs, Michael

    2016-01-01

    Both classical social psychological theories and recent formal models of opinion differentiation and bi-polarization assign a prominent role to negative social influence. Negative influence is defined as shifts away from the opinion of others and hypothesized to be induced by discrepancy with or disliking of the source of influence. There is strong empirical support for the presence of positive social influence (a shift towards the opinion of others), but evidence that large opinion differences or disliking could trigger negative shifts is mixed. We examine positive and negative influence with controlled exposure to opinions of other individuals in one experiment and with opinion exchange in another study. Results confirm that similarities induce attraction, but results do not support that discrepancy or disliking entails negative influence. Instead, our findings suggest a robust positive linear relationship between opinion distance and opinion shifts. PMID:27333160

  18. Comparative genome sequencing of Drosophila pseudoobscura: Chromosomal, gene, and cis-element evolution

    DEFF Research Database (Denmark)

    Richards, Stephen; Liu, Yue; Bettencourt, Brian R.

    2005-01-01

    years (Myr) since the pseudoobscura/melanogaster divergence. Genes expressed in the testes had higher amino acid sequence divergence than the genome-wide average, consistent with the rapid evolution of sex-specific proteins. Cis-regulatory sequences are more conserved than random and nearby sequences......We have sequenced the genome of a second Drosophila species, Drosophila pseudoobscura, and compared this to the genome sequence of Drosophila melanogaster, a primary model organism. Throughout evolution the vast majority of Drosophila genes have remained on the same chromosome arm, but within each...... between the species-but the difference is slight, suggesting that the evolution of cis-regulatory elements is flexible. Overall, a pattern of repeat-mediated chromosomal rearrangement, and high coadaptation of both male genes and cis-regulatory sequences emerges as important themes of genome divergence...

  19. Situation Concerning Public Information about and Involvement in the Decision-Making Processes in the Nuclear Sector. Public Opinion Review.

    Energy Technology Data Exchange (ETDEWEB)

    Prades, A.; Sala, R.; Lopez, M.

    2006-07-01

    This report summarizes the CIEMAT's contribution to the study {sup S}ituation concerning Public Information about and Involvement in the Decision-Making Processes in the Nuclear Sector{sup ,} contract number TREN/ 04/NUC/ S07.39556 between the European Commission and Mutadis Consultants. The research was composed by Mutadis Consultants and CEPN (Nuclear Protection Evaluation Centre) (France), University of Aberdeen (UK) and CIEMAT (Spain). The objective of the project was to build a detailed overview of the EU situation regarding information and participation practices in the nuclear domain, provide an elaborated assessment, and to produce reporting and recommendations in the field. CIEMAT contribution' focused on the review of public opinion polis. Thus, Eurobarometers Standard Surveys (EBs) were analysed to report about the European citizens' public opinion regarding public Information and participation in the nuclear field. Additionally, the International Social Survey Program (ISSP), and some additional national polis were analysed. In terms of the EU public opinion, the follow up of the public information and participation domains receiving as much attention as necessary. Extremely few questions dealing with the subject were identified in the Eurobarometers, the national polis and the ISSP (International Social Survey Program) surveys reviewed in this study. An unambiguous illustration of this lack of attention is the fact that no questions dealing with public participation issues emerged in the {sup n}uclear EBs{sup u}ntil 1998. Even though, Eurobarometers (EBs) still provide an invaluable source of information on the topics we are interested on at the EU allowing longitudinal descriptions (trend analysis) of some key issues in our area of interest. (Author) 11 refs.

  20. STUDENT OPINIONS ON MANAGEMENT OF DISTANCE EDUCATION APPLICATIONS

    Directory of Open Access Journals (Sweden)

    Celal GULSEN

    2014-07-01

    Full Text Available Traditional education systems can sometimes become inadequate in the face of technological developments. Individuals, whose educational needs cannot be met by traditional education systems, can tend to search for alternatives and can have different demands in order to meet with these needs. These demands of the individuals can be reciprocated by managements and internet-based education methods, which remove limitations of time and space, provide facilities and equal opportunities, comply with student-centered educational approach and use computer and internet technologies, can be put into practice. Appearing before us sometimes as an alternative to the traditional education and sometimes as a support, these applications began to occupy an important place in the education systems of our era. This study, which was conducted by general survey method in view of this importance, aims to learn opinions of “masters’ students on the efficiency of distance education applications.” Survey of “Distant Education and Technologies Assessment,” developed by Aktas (2008 and adapted to Istanbul sampling by the researcher, was used in order to determine opinions. University students, who are doing masters without thesis at Social Sciences Institute Educational Administration Supervision Planning and Economics Department of Fatih University in 2013-2014 academic years, constitute the study group of the research. All of the students in the study group were reached. As a result of the study, masters’ students believe that “distance education applications” fills a very important void for individuals that experience difficulties especially in time management despite some of its inconveniencies. By looking at the results of the study, it is suggested that measures, which provide further dissemination of distance education application by will improve their technical competencies, should be taken.

  1. KINETICS OF SUBSTITUTION OF CIS-BIS(MALONATO ...

    African Journals Online (AJOL)

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    In this process, it indicated that the substitution reaction occurs through an Ia mechanism in the ... isotopic water exchange and other anation processes. ... The potassium salt of cis-bis(malonato)diaquochromate(III) was prepared by a reported [26] ... of the synthesized metal complex showed maxima at 415 nm (ε = 41.6 M-1 ...

  2. Backlash or a Positive Response?: Public Opinion of LGB Issues After Obergefell v. Hodges.

    Science.gov (United States)

    Kazyak, Emily; Stange, Mathew

    2018-01-10

    Following Obergefell v. Hodges, same-sex marriage remains controversial and anti-LGBT state legislation has been passed, which raises questions about whether the Supreme Court's ruling may have created a backlash. We use data from two waves of a general population survey of Nebraskans conducted before and after the decision to answer three questions. First, we test three theories of how the court decision influenced public opinion. We find that support for same-sex marriage was significantly higher following the ruling, suggesting that there was not a backlash to it. Second, we assess whether people perceive that the court accurately reflects the public's opinion. We find that people who favor same-sex marriage are more likely to think that the ruling refects public opinion very well; those who oppose same-sex marriage are more likely to think that the ruling does not at all reflect public opinion. Third, we examine the association between discussing gay rights and support for same-sex marriage, finding that those who talk about LGB issues very often are more likely to favor same-sex marriage. We discuss the implications of these findings in relation to two of the themes of this special issue: the influence of marriage equality on Americans' understandings of marriage and the impact of marriage equality on future LGBT activism.

  3. Participation of Peoples’ Friendship University of Russia in the activities of CIS Network University

    Directory of Open Access Journals (Sweden)

    S A Kovalenko

    2014-12-01

    Full Text Available The article analyzes processes in the sphere of humanitarian cooperation in the CIS region and PFUR contribution to the development of educational area as a key of success in strengthening intercultural relations and academic mobility in the CIS countries.

  4. cis-Apa: a practical linker for the microwave-assisted preparation of cyclic pseudopeptides via RCM cyclative cleavage.

    Science.gov (United States)

    Baron, Alice; Verdié, Pascal; Martinez, Jean; Lamaty, Frédéric

    2011-02-04

    A new linker cis-5-aminopent-3-enoic acid (cis-Apa) was prepared for the synthesis of cyclic pseudopeptides by cyclization-cleavage by using ring-closing methatesis (RCM). We developed a new synthetic pathway for the preparation of the cis-Apa linker that was tested in the cyclization-cleavage process of different RGD peptide sequences. Different macrocyclic peptidomimetics were prepared by using this integrated microwave-assisted method, showing that the readily available cis-Apa amino acid is well adapted as a linker in the cyclization-cleavage process.

  5. A "miracle" cancer drug in the era of social media: A survey of Brazilian oncologists' opinions and experience with phosphoethanolamine.

    Science.gov (United States)

    Rêgo, Juliana Florinda M; Lopes, Gilberto; Riechelmann, Rachel P; Sternberg, Cinthya; Ferrari, Claudio; Fernandes, Gustavo

    2017-01-01

    Patients who are treating cancer have often used alternative therapies. In the internet era, information can be broadcasted widely, and this happened with phosphoethanolamine in Brazil, where this substance was claimed by the population to be the "cure for cancer." This is a cross-sectional study developed by the Brazilian Society of Clinical Oncology (SBOC). An objectively structured questionnaire was sent by e-mail and SMS to active MDs members of the SBOC. Descriptive statistics was used to evaluate the data. Statistical significance between the variables was tested by Pearson's Chi-squared test (p<0.05 was considered significance). The survey was sent to 1,072 oncologists, and 398 (37.1%) answered at least part of it. One hundred and fifteen (28.9%) had followed patients who had used phosphoethanolamine. Among these, 14 (12.2%) observed adverse events and four (3.5%) attributed clinical benefit to the substance. Most of the oncologists (n=331; 83.2%) believe that it should only be used as part of a clinical trial protocol. Most physicians did not recommend this drug to their patients (n=311; 78.1%). Oncologists in Southeast, South and Midwest Brazil were more likely to have patients taking the drug compared to the Northern and Northeastern regions. This is the first survey to assess the opinion and experience of oncologists about this alternative therapy. Most oncologists in Brazil do not believe that synthetic phosphoethanolamine is active in cancer treatment, do not recommend its use without proper evaluation, and state that it should only be available to patients in the context of clinical trials.

  6. Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo.

    Science.gov (United States)

    Aliwarga, Theresa; Raccor, Brianne S; Lemaitre, Rozenn N; Sotoodehnia, Nona; Gharib, Sina A; Xu, Libin; Totah, Rheem A

    2017-11-01

    Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid (AA) oxidation that have important cardioprotective and signaling properties. AA is an ω-6 polyunsaturated fatty acid (PUFA) that is prone to autoxidation. Although hydroperoxides and isoprostanes are major autoxidation products of AA, EETs are also formed from the largely overlooked peroxyl radical addition mechanism. While autoxidation yields both cis- and trans-EETs, cytochrome P450 (CYP) epoxygenases have been shown to exclusively catalyze the formation of all regioisomer cis-EETs, on each of the double bonds. In plasma and red blood cell (RBC) membranes, cis- and trans-EETs have been observed, and both have multiple physiological functions. We developed a sensitive ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) assay that separates cis- and trans- isomers of EETs and applied it to determine the relative distribution of cis- vs. trans-EETs in reaction mixtures of AA subjected to free radical oxidation in benzene and liposomes in vitro. We also determined the in vivo distribution of EETs in several tissues, including human and mouse heart, and RBC membranes. We then measured EET levels in heart and RBC of young mice compared to old. Formation of EETs in free radical reactions of AA in benzene and in liposomes exhibited time- and AA concentration-dependent increase and trans-EET levels were higher than cis-EETs under both conditions. In contrast, cis-EET levels were overall higher in biological samples. In general, trans-EETs increased with mouse age more than cis-EETs. We propose a mechanism for the non-enzymatic formation of cis- and trans-EETs involving addition of the peroxyl radical to one of AA's double bonds followed by bond rotation and intramolecular homolytic substitution (S H i). Enzymatic formation of cis-EETs by cytochrome P450 most likely occurs via a one-step concerted mechanism that does not allow bond rotation. The ability to accurately measure

  7. Characterization of STAT5B phosphorylation correlating with expression of cytokine-inducible SH2-containing protein (CIS).

    Science.gov (United States)

    Cooper, John C; Boustead, Jared N; Yu, Chao-Lan

    2006-06-01

    Cytokine-inducible SH2-containing protein (CIS) is the first identified member of genes encoding for the suppressor of cytokine signaling (SOCS). CIS is also a well-known target gene of signal transducer and activator of transcription 5 (STAT5) pathways, providing normal negative feedback control of signaling by cytokines and growth factors. Three other SOCS genes, SOCS1, SOCS2, and SOCS3, can be silenced by DNA hypermethylation in human cancers, suggesting a potential mechanism for constitutive STAT activation. However, it is not known whether CIS expression is similarly perturbed in tumor cells. We report here the absence of CIS expression in T lymphoma LSTRA that overexpresses the Lck protein tyrosine kinase and exhibits elevated STAT5 activity. Pervanadate-induced CIS expression and STAT5 binding to the CIS promoter in vivo over a short time course implies that mechanisms other than DNA hypermethylation may contribute to defective CIS expression in LSTRA cells. Comparison with cytokine-dependent BaF3 cells stimulated with interleukin-3 (IL-3) further reveals that CIS induction correlates with specific STAT5b post-translational modifications. It exhibits as the slowest migrating form through SDS-polyacrylamide gel electrophoresis (SDS-PAGE) analysis. This distinctly modified STAT5b is the predominant form that binds to the consensus STAT5 sites in the CIS promoter and accumulates in the nucleus. In vitro phosphatase assays and phosphoamino acid analysis suggest the involvement of phosphorylation on residues other than the highly conserved tyrosine and serine sites in this distinct STAT5b mobility shift. All together, our results provide a novel link between incomplete STAT5b phosphorylation and defective SOCS gene expression in cancer cells.

  8. 9-cis-retinoic acid represses estrogen-induced expression of the very low density apolipoprotein II gene.

    Science.gov (United States)

    Schippers, I J; Kloppenburg, M; Snippe, L; Ab, G

    1994-11-01

    The chicken very low density apolipoprotein II (apoVLDLII) gene is estrogen-inducible and specifically expressed in liver. We examined the possible involvement of the retinoid X receptor (RXR) and its ligand 9-cis-retinoic acid (9-cis-RA) in the activation of the apoVLDLII promoter. We first concentrated on a potential RXR recognition site, which deviates at only one position from a perfect direct A/GGGTCA repeat spaced by one nucleotide (DR-1) and was earlier identified as a common HNF-4/COUP-TF recognition site. However, band shift analysis revealed that this imperfect DR-1 motif does not interact with RXR alpha-homodimers. In accordance with this observation we found that this regulatory element does not mediate transactivation through RXR alpha in the presence of 9-cis-RA. However, our experiments revealed another, unexpected, effect of 9-cis-RA. Instead of stimulating, 9-cis-RA attenuated estrogen-induced expression of transfected estrogen-responsive VLDL-CAT reporter plasmids. This repression appeared to take place through the main estrogen response element (ERE) of the gene. Importantly, 9-cis-RA also strongly repressed the estrogen-induced expression of the endogenous apoVLDLII gene in cultured chicken hepatoma cells.

  9. Manganese catalyzed cis-dihydroxylation of electron deficient alkenes with H(2)O(2).

    Science.gov (United States)

    Saisaha, Pattama; Pijper, Dirk; van Summeren, Ruben P; Hoen, Rob; Smit, Christian; de Boer, Johannes W; Hage, Ronald; Alsters, Paul L; Feringa, Ben L; Browne, Wesley R

    2010-10-07

    A practical method for the multigram scale selective cis-dihydroxylation of electron deficient alkenes such as diethyl fumarate and N-alkyl and N-aryl-maleimides using H(2)O(2) is described. High turnovers (>1000) can be achieved with this efficient manganese based catalyst system, prepared in situ from a manganese salt, pyridine-2-carboxylic acid, a ketone and a base, under ambient conditions. Under optimized conditions, for diethyl fumarate at least 1000 turnovers could be achieved with only 1.5 equiv. of H(2)O(2) with d/l-diethyl tartrate (cis-diol product) as the sole product. For electron rich alkenes, such as cis-cyclooctene, this catalyst provides for efficient epoxidation.

  10. Current and future perspectives on lumbar degenerative disc disease: a UK survey exploring specialist multidisciplinary clinical opinion

    Science.gov (United States)

    McGregor, Alison H

    2016-01-01

    Objectives Despite lumbar degenerative disc disease (LDDD) being significantly associated with non-specific low back pain and effective treatment remaining elusive, specialist multidisciplinary clinical stakeholder opinion remains unexplored. The present study examines the views of such experts. Design A reliable and valid electronic survey was designed to establish trends using theoretical constructs relating to current assessment and management practices. Clinicians from the Society of Back Pain Research (SBPR) UK were invited to take part. Quantitative data were collated and coded using Bristol Online Surveys (BOS) software, and content analysis was used to systematically code and categorise qualitative data. Setting Specialist multidisciplinary spinal interest group in the UK. Participants 38/141 clinically active, multidisciplinary SBPR members with specialist spinal interest participated. Among them, 84% had >9 years postgraduate clinical experience. Interventions None. Outcome measures Frequency distributions were used to establish general trends in quantitative data. Qualitative responses were coded and categorised in relation to each theme and percentage responses were calculated. Results LDDD symptom recurrence, in the absence of psychosocial influence, was associated with physical signs of joint stiffness (26%), weakness (17%) and joint hypermobility (6%), while physical factors (21%) and the ability to adapt (11%) were postulated as reasons why some experience pain and others do not. No one management strategy was supported exclusively or with consensus. Regarding effective modalities, there was no significant difference between allied health professional and medic responses (p=0.1–0.8). The future of LDDD care was expressed in terms of improvements in patient communication (35%), patient education (38%) and treatment stratification (24%). Conclusions Results suggest that multidisciplinary expert spinal clinicians appear to follow UK

  11. Survey of Tsuruga inhabitants concerning radiation and its risks

    International Nuclear Information System (INIS)

    Shinoda, Yoshihiko; Yamano, Naoki

    2015-01-01

    The Fukushima Daiichi nuclear accident has led to changes in the acceptance of nuclear power in many people. The authors conducted an opinion survey of 300 adult inhabitants of Tsuruga city in Fukui prefecture, Japan. The aim of this survey is to obtain people's opinions concerning radiation and its risks. Authors classified Tsuruga inhabitants on the basis of responses to questions on the concept and knowledge of risk and the cognition of radiation by factor and cluster analyses of multivariable analysis. Using the results of these analyses, Tsuruga inhabitants have been assigned to five categories: “acceptance group,” “anxiety group,” and three intermediate groups. (author)

  12. Discrete Opinion Dynamics on Online Social Networks

    International Nuclear Information System (INIS)

    Hu Yan-Li; Bai Liang; Zhang Wei-Ming

    2013-01-01

    This paper focuses on the dynamics of binary opinions {+1, −1} on online social networks consisting of heterogeneous actors. In our model, actors update their opinions under the interplay of social influence and self- affirmation, which leads to rich dynamical behaviors on online social networks. We find that the opinion leading to the consensus features an advantage of the initially weighted fraction based on actors' strength over the other, instead of the population. For the role of specific actors, the consensus converges towards the opinion that a small fraction of high-strength actors hold, and individual diversity of self-affirmation slows down the ordering process of consensus. These indicate that high-strength actors play an essential role in opinion formation with strong social influence as well as high persistence. Further investigations show that the initial fraction of high-strength actors to dominate the evolution depends on the heterogeneity of the strength distribution, and less high-strength actors are needed in the case of a smaller exponent of power-law distribution of actors' strength. Our study provides deep insights into the role of social influence and self-affirmation on opinion formation on online social networks. (general)

  13. Discrete Opinion Dynamics on Online Social Networks

    Science.gov (United States)

    Hu, Yan-Li; Bai, Liang; Zhang, Wei-Ming

    2013-01-01

    This paper focuses on the dynamics of binary opinions {+1, -1} on online social networks consisting of heterogeneous actors. In our model, actors update their opinions under the interplay of social influence and self- affirmation, which leads to rich dynamical behaviors on online social networks. We find that the opinion leading to the consensus features an advantage of the initially weighted fraction based on actors' strength over the other, instead of the population. For the role of specific actors, the consensus converges towards the opinion that a small fraction of high-strength actors hold, and individual diversity of self-affirmation slows down the ordering process of consensus. These indicate that high-strength actors play an essential role in opinion formation with strong social influence as well as high persistence. Further investigations show that the initial fraction of high-strength actors to dominate the evolution depends on the heterogeneity of the strength distribution, and less high-strength actors are needed in the case of a smaller exponent of power-law distribution of actors' strength. Our study provides deep insights into the role of social influence and self-affirmation on opinion formation on online social networks.

  14. Opinion data mining based on DNA method and ORA software

    Science.gov (United States)

    Tian, Ru-Ya; Wu, Lei; Liang, Xiao-He; Zhang, Xue-Fu

    2018-01-01

    Public opinion, especially the online public opinion is a critical issue when it comes to mining its characteristics. Because it can be formed directly and intensely in a short time, and may lead to the outbreak of online group events, and the formation of online public opinion crisis. This may become the pushing hand of a public crisis event, or even have negative social impacts, which brings great challenges to the government management. Data from the mass media which reveal implicit, previously unknown, and potentially valuable information, can effectively help us to understand the evolution law of public opinion, and provide a useful reference for rumor intervention. Based on the Dynamic Network Analysis method, this paper uses ORA software to mine characteristics of public opinion information, opinion topics, and public opinion agents through a series of indicators, and quantitatively analyzed the relationships between them. The results show that through the analysis of the 8 indexes associating with opinion data mining, we can have a basic understanding of the public opinion characteristics of an opinion event, such as who is important in the opinion spreading process, the information grasping condition, and the opinion topics release situation.

  15. 2013 Gulf of Mexico SPCE angler survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This survey provides economic data related to marine recreational fishing in the Gulf of Mexico. The data collected include preference and opinion information...

  16. Genome-wide prediction of cis-regulatory regions using supervised deep learning methods.

    Science.gov (United States)

    Li, Yifeng; Shi, Wenqiang; Wasserman, Wyeth W

    2018-05-31

    In the human genome, 98% of DNA sequences are non-protein-coding regions that were previously disregarded as junk DNA. In fact, non-coding regions host a variety of cis-regulatory regions which precisely control the expression of genes. Thus, Identifying active cis-regulatory regions in the human genome is critical for understanding gene regulation and assessing the impact of genetic variation on phenotype. The developments of high-throughput sequencing and machine learning technologies make it possible to predict cis-regulatory regions genome wide. Based on rich data resources such as the Encyclopedia of DNA Elements (ENCODE) and the Functional Annotation of the Mammalian Genome (FANTOM) projects, we introduce DECRES based on supervised deep learning approaches for the identification of enhancer and promoter regions in the human genome. Due to their ability to discover patterns in large and complex data, the introduction of deep learning methods enables a significant advance in our knowledge of the genomic locations of cis-regulatory regions. Using models for well-characterized cell lines, we identify key experimental features that contribute to the predictive performance. Applying DECRES, we delineate locations of 300,000 candidate enhancers genome wide (6.8% of the genome, of which 40,000 are supported by bidirectional transcription data), and 26,000 candidate promoters (0.6% of the genome). The predicted annotations of cis-regulatory regions will provide broad utility for genome interpretation from functional genomics to clinical applications. The DECRES model demonstrates potentials of deep learning technologies when combined with high-throughput sequencing data, and inspires the development of other advanced neural network models for further improvement of genome annotations.

  17. Survey of diagnostic and treatment practices for multiple sclerosis in Europe

    DEFF Research Database (Denmark)

    Fernández, O; Delvecchio, M; Edan, G

    2017-01-01

    BACKGROUND AND PURPOSE: Up-to-date information is needed on the extent to which neurologists treating multiple sclerosis (MS) in Europe are integrating rapidly evolving diagnostic criteria, disease-modifying therapies and recommendations for monitoring disease activity into their clinical practice...... syndrome (CIS), relapsing-remitting MS (RRMS) and RRMS with breakthrough disease. RESULTS: Multiple sclerosis neurologists from 11 European countries responded to survey 1 (n = 233) and survey 2 (n = 171). Respondents agreed that they would not treat the patients in the RIS or CIS cases but would treat...... a patient with a relatively mild form of RRMS. Choice of treatment was evenly distributed among first-line injectables and oral treatments for mild RRMS, and moved to second-line treatment as the RRMS case increased in severity. Additional results on RRMS with breakthrough disease are presented. CONCLUSIONS...

  18. Speech language pathologists' opinions of constraint-induced language therapy.

    Science.gov (United States)

    Page, Stephen J; Wallace, Sarah E

    2014-01-01

    Constraint-induced language therapy (CILT) has received recent attention as a possible intervention to improve expressive language in people with nonfluent aphasia. Difficulties have been reported with the practical implementation of constraint-induced movement therapy due to its intensive treatment parameters. It remains unknown whether similar challenges may exist with CILT. To determine the opinions of speech-language pathologists (SLPs) about CILT for people with nonfluent aphasia. One hundred sixty-seven SLPs completed an electronic survey assessing their opinions of various aspects of CILT. Over 60% of participants felt that people with aphasia would be very unlikely or somewhat unlikely to adhere to CILT. The majority felt that people with aphasia would hold high or moderate concerns with the number of hours spent in therapy (high, 41.8%; moderate, 31.4%), the number of days spent in therapy (high, 44.4%; moderate, 24.8%), likelihood for managed care reimbursement (high, 74.8%; moderate, 15.2%), and other logistical issues (high, 39.2%; moderate, 30.7%). With respect to providing CILT, participants cited the number of hours of therapy (high, 37.3%; moderate, 21.6%) and the number of consecutive days of therapy (high, 29.4%; moderate, 20.3%) as concerns. There were 70.6% who indicated that their facilities lacked resources to provide CILT, and 90.9% felt that most facilitates do not have the resources to provide CILT. Some SLPs hold significant concerns with the administration of CILT, particularly related to its dosing and reimbursement parameters. Additional work is needed to investigate the issues that were identified in this survey using qualitative methods with SLPs and people with aphasia and to examine modified CILT protocols.

  19. Discovery of cis-elements between sorghum and rice using co-expression and evolutionary conservation

    Directory of Open Access Journals (Sweden)

    Haberer Georg

    2009-06-01

    Full Text Available Abstract Background The spatiotemporal regulation of gene expression largely depends on the presence and absence of cis-regulatory sites in the promoter. In the economically highly important grass family, our knowledge of transcription factor binding sites and transcriptional networks is still very limited. With the completion of the sorghum genome and the available rice genome sequence, comparative promoter analyses now allow genome-scale detection of conserved cis-elements. Results In this study, we identified thousands of phylogenetic footprints conserved between orthologous rice and sorghum upstream regions that are supported by co-expression information derived from three different rice expression data sets. In a complementary approach, cis-motifs were discovered by their highly conserved co-occurrence in syntenic promoter pairs. Sequence conservation and matches to known plant motifs support our findings. Expression similarities of gene pairs positively correlate with the number of motifs that are shared by gene pairs and corroborate the importance of similar promoter architectures for concerted regulation. This strongly suggests that these motifs function in the regulation of transcript levels in rice and, presumably also in sorghum. Conclusion Our work provides the first large-scale collection of cis-elements for rice and sorghum and can serve as a paradigm for cis-element analysis through comparative genomics in grasses in general.

  20. Future CIS Manufacturing Technology Development: Final Report, 8 July 1998--17 October 2001

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, T. J.; Crisalle, O. D.; Li, S. S.; Holloway, P. H.

    2003-06-01

    The University of Florida served as the basis for educating 12 graduate students in the area of photovoltaics engineering and research with a focus on thin-film CIS manufacturing technologies. A critical assessment of the thermodynamic data and of the phase diagrams for the Cu-Se and In-Se binary systems were carried out. We investigated the use of two novel precursor structures that used stacked In-Se and Cu-Se binary layers instead of conventional elemental layers, followed by rapid thermal processing (RTP) to produce CIS films. We investigated the evolution of electrical and microstructural properties of sputter-deposited ZnO:Al thin films. An assessment of the thermodynamics of the pseudobinary Cu2Se-Ga2Se3 system was done by using available experimental data, as well as an empirical method for estimating interactions in semiconductor solid solutions. Optimization studies were conducted to characterize the RTP of binary bilayer precursors for CIS synthesis using a newly acquired AG Associates Heatpulse furnace. Progress was made on the calculation of the 500C isothermal section of the phase diagram of the ternary Cu-In-Se system. Pursuit of developing alternative buffer layers for Cd-free CIS-based solar cells using a chemical-bath deposition (CBD) process has resulted in specific recipes for deposition. A rigorous model has been derived to predict the metal mass fluxes produced by conical thermal effusion sources. A two-dimensional model of the heat transfer was developed to model the substrate temperature distribution in the UF PMEE Reactor that features a rotating platen/substrates and effusion sources. We have grown and characterized polycrystalline CIS epitaxial films on single-crystal GaAs substrates under conditions that enhance the influence of surface effects on the resulting films and their properties. Progress was made on the study of CIS and CGS single-crystal growth, along with accompanying morphological and compositional characterizations. We have

  1. Getting a Second Opinion Before Surgery

    Science.gov (United States)

    ... for a second opinion before surgery. When your doctor says you have a health problem that needs surgery, you have the right to: • Know and understand your treatment choices • Have another doctor look at those choices with you (second opinion) • ...

  2. Social opinion dynamics is not chaotic

    Science.gov (United States)

    Lim, Chjan; Zhang, Weituo

    2016-08-01

    Motivated by the research on social opinion dynamics over large and dense networks, a general framework for verifying the monotonicity property of multi-agent dynamics is introduced. This allows a derivation of sociologically meaningful sufficient conditions for monotonicity that are tailor-made for social opinion dynamics, which typically have high nonlinearity. A direct consequence of monotonicity is that social opinion dynamics is nonchaotic. A key part of this framework is the definition of a partial order relation that is suitable for a large class of social opinion dynamics such as the generalized naming games. Comparisons are made to previous techniques to verify monotonicity. Using the results obtained, we extend many of the consequences of monotonicity to this class of social dynamics, including several corollaries on their asymptotic behavior, such as global convergence to consensus and tipping points of a minority fraction of zealots or leaders.

  3. To drill or not to drill? An econometric analysis of US public opinion

    International Nuclear Information System (INIS)

    Mukherjee, Deep; Rahman, Mohammad Arshad

    2016-01-01

    Offshore drilling in the United States (US) has been the subject of public and political discourse due to multiple reasons which include economic impact, energy security, and environmental hazard. Consequently, several polls have been conducted over time to gauge public attitude towards offshore drilling. Nevertheless, the economic literature on this issue is sparse. This paper contributes to the literature and analyzes support for offshore drilling based on demographic, economic, social, belief, and shock (e.g. spill) factors. The data is taken from ten nationwide surveys conducted before, during and after the British Petroleum (BP) oil spill and analyzed within the framework of discrete choice model. The results from an ordinal probit model demonstrate that age, annual household income, affiliation to Republican Party, and residence in oil-rich states positively affect the probability of strong support and reduce the probability of strong opposition for offshore drilling. In contrast, the female gender, higher education, association to Democratic Party, and environmental concern affect opinion in opposite direction. Marginal effects show that belief about environmental consequences of drilling has the highest impact on opinion. Binary probit model also yields a similar result and suggests that BP oil disaster resulted in a transient decrease in support for offshore drilling. - Highlights: •US public opinion on offshore drilling is analyzed based on ten national polls. •Ordinal and binary probit models are utilized to identify the underlying factors that shape public opinion. •Belief about environmental cost of drilling and educational attainment have the highest negative impact on opinion. •Age, income, affiliation to Republican party and oil-rich states positively affect support for drilling. •BP oil spill resulted in a transient decrease in support for offshore drilling.

  4. THE OPINION OF CROWD PARTICIPATORY FOR OPENSTREETMAP: A SURVEY IN CHINA

    Directory of Open Access Journals (Sweden)

    J. Shen

    2018-04-01

    Full Text Available At the present, OpenStreetMap (OSM is considered as one of the most successful and popular VGI (Volunteered Geographic Information projects. It provides a platform that all the registered members coming from different areas in the world can cooperate with each other to mapping our world. Besides, OSM attracts more and more people, companies and even the governmental agencies because of its free and open source. Studies have proofed that both the quantity and quality of OSM data in several western countries, i.e. Germany, France and the Netherland are even better than the authority data. In recent years, the quantity of the OSM data and the number of contributors in China increased rapidly, but the overall distribution of OSM data is very fit with the distribution of population and the economic development and it displays an uneven development in different provinces and cities in China. Besides, the state of the OSM in China is just similar to that in Germany in 2010 in terms of data quantity and quality, although China is about 25 times to Germany regarding land area and the smartphone penetration in China and Germany does not have a large distance (51.7 % to 68.8 %. Why is the development of OSM in China so poor and backward when comparing that with western countries, although the environment in hardware and software in China are similar to the western countries? Attempting to answer this question, this paper presents a user survey in China. Mainly, knowledges and experiences about OSM and OSM contribution were asked in the user survey. The user survey was conducted both by paper and pen and by using online platform. Totally, over 1200 participants with the age range from 15 to 80 and a huge diverse of background took part in the user survey. In this paper, we would like to describe the design of the questions for the user survey at first. Then we will demonstrate the results of the user survey, as well as the analysis and conclusions

  5. The Opinion of Crowd Participatory for Openstreetmap: a Survey in China

    Science.gov (United States)

    Shen, J.; Yang, S.; Zang, K.; Zhou, J.; Fan, H.; Mao, B.

    2018-04-01

    At the present, OpenStreetMap (OSM) is considered as one of the most successful and popular VGI (Volunteered Geographic Information) projects. It provides a platform that all the registered members coming from different areas in the world can cooperate with each other to mapping our world. Besides, OSM attracts more and more people, companies and even the governmental agencies because of its free and open source. Studies have proofed that both the quantity and quality of OSM data in several western countries, i.e. Germany, France and the Netherland are even better than the authority data. In recent years, the quantity of the OSM data and the number of contributors in China increased rapidly, but the overall distribution of OSM data is very fit with the distribution of population and the economic development and it displays an uneven development in different provinces and cities in China. Besides, the state of the OSM in China is just similar to that in Germany in 2010 in terms of data quantity and quality, although China is about 25 times to Germany regarding land area and the smartphone penetration in China and Germany does not have a large distance (51.7 % to 68.8 %). Why is the development of OSM in China so poor and backward when comparing that with western countries, although the environment in hardware and software in China are similar to the western countries? Attempting to answer this question, this paper presents a user survey in China. Mainly, knowledges and experiences about OSM and OSM contribution were asked in the user survey. The user survey was conducted both by paper and pen and by using online platform. Totally, over 1200 participants with the age range from 15 to 80 and a huge diverse of background took part in the user survey. In this paper, we would like to describe the design of the questions for the user survey at first. Then we will demonstrate the results of the user survey, as well as the analysis and conclusions, which can be drawn from

  6. Are public opinion polls self-fulfilling prophecies?

    Directory of Open Access Journals (Sweden)

    David Rothschild

    2014-08-01

    Full Text Available Psychologists have long observed that people conform to majority opinion, a phenomenon sometimes referred to as the ‘bandwagon effect’. In the political domain people learn about prevailing public opinion via ubiquitous polls, which may produce a bandwagon effect. Newer types of information – published probabilities derived from prediction market contract prices and aggregated polling summaries – may have similar effects. Consequently, polls can become self-fulfilling prophecies whereby majorities, whether in support of candidates or policies, grow in a cascading manner. Despite increased attention to whether the measurement of public opinion can itself affect public opinion, the existing empirical literature is surprisingly limited on the bandwagon effects of polls. To address this gap, we conducted an experiment on a diverse national sample in which we randomly assigned people to receive information about different levels of support for three public policies. We find that public opinion as expressed through polls affects individual-level attitudes, although the size of the effect depends on issue characteristics.

  7. The opinions and experiences of family physicians regarding direct-to-consumer advertising.

    Science.gov (United States)

    Lipsky, M S; Taylor, C A

    1997-12-01

    The use of direct-to-consumer advertising (DTCA) by pharmaceutical companies is increasing. Our study examines the opinions and experiences of family physicians concerning DTCA. A survey instrument designed to elicit the opinions, experiences, and perceptions of family physicians about DTCA was sent to a 2% (N = 880) systematic sampling of active physician members of the American Academy of Family Physicians. Descriptive statistics were used to analyze responses with t tests and chi 2 tests for independence used to examine subgroup response differences. Four hundred fifty-four (52%) physicians responded to the survey. Most physicians (95%) had encountered DTCA personally, and had been approached by an average of 7 patients over the previous 6 months with requests for specific prescription drugs. Prescription antihistamines and antihypertensive drugs were the most commonly requested. Overall, 80% of the physician respondents believed that print DTCA was not a good idea, while 84% expressed negative feelings about television and radio advertising. Both groups cited "misleading biased view" and "increased costs" as the most common disadvantages. Some reported benefits included "better informed patients" and "promoting physician-patient communication." Overall, the study group physicians had negative feelings about DTCA in both print and electronic media. Studies directly examining patient perspectives, as well as cost benefits, are necessary to test the validity of the physicians' perceptions about DTCA.

  8. E-TOURISM SERVICES IN POLISH TOURISTS' OPINIONS

    Directory of Open Access Journals (Sweden)

    Joanna Papińska-Kacperek

    2013-07-01

    Full Text Available E-tourism is most often related only with web pages of travel agencies or aggregators offering many services, where it is possible to make transactions electronically. Whereas many applications and devices are applied in tourism, like the audio guides and mobile guides (sometimes with augmented reality functions, electronic cards in museums, 2D codes systems, web pages for individual tourists, geographic information systems (e.g. Google Street View, social network sites recommendation, and profiles of cities on social networks sites like Facebook. Polish tourists' opinions about mentioned innovative tools will be presented as the report from the survey conducted among students and graduates from three Polish universities. The objectives of the study are: investigating the popularity of e-tourist services in Poland and verifying whether municipal authorities promote e-tourism initiatives.

  9. ERP IN THE PRODUCTION AREA: USER’S OPINIONS ABOUT

    Directory of Open Access Journals (Sweden)

    Andre Luiz Pestana de Oliveira

    2010-01-01

    Full Text Available The study verified the production area’s key user opinions about needs being met by ERPthrough a survey conducted within industries from the State of São Paulo. The survey instrumentis composed of 28 activities related to the production area, using the literature review onproduction management and ERP as a basis. Also, four dimensions for production activities weredefined: Inventory Management Policies, Forecasts, MRP and MRP II. Activities were evaluatedaccording to five different criteria: Needs Being Met, Ease of Use, Parameterization,Customization and Training. The questionnaire was answered by managers from 46 industries,composing a non-probabilistic sample with an accessibility criterion. The research isexploratory. The analysis of the obtained data broadly showed that ERPs meet the expectationsof production managers. However, its most noteworthy aspect is the high number of activitiesthat are not used by companies. It was noted that the higher the number of used activities, thehigher the level of perception of needs being met.

  10. Monte Carlo simulations of a model for opinion formation

    Science.gov (United States)

    Bordogna, C. M.; Albano, E. V.

    2007-04-01

    A model for opinion formation based on the Theory of Social Impact is presented and studied by means of numerical simulations. Individuals with two states of opinion are impacted due to social interactions with: i) members of the society, ii) a strong leader with a well-defined opinion and iii) the mass media that could either support or compete with the leader. Due to that competition, the average opinion of the social group exhibits phase-transition like behaviour between different states of opinion.

  11. Second medical opinions: the views of oncology patients and their physicians.

    Science.gov (United States)

    Philip, Jennifer; Gold, Michelle; Schwarz, Max; Komesaroff, Paul

    2010-09-01

    Second medical opinions (SMOs) are common in oncology practice, but the nature of these consultations has received relatively little attention. This study examines the views of patients with advanced cancer and their physicians of SMOs. Parallel, concurrent surveys were developed for patients and physicians. The first was distributed to outpatients with advanced cancer-attending specialist clinics in an Australian quaternary hospital. The second survey, developed on the basis of results of exploratory interviews with medical oncologists, was distributed to medical oncologists in Australia. Seventeen of fifty two (33%) patients had sought a SMO, most commonly prompted by concerns around communication with their first doctor, the extreme and desperate nature of their medical condition and the need for reassurance. Most (94%) patients found the SMO helpful, with satisfaction related to improved communication and reassurance. Patients were concerned that seeking a second medical opinion may affect their relationship with their primary doctor. Most physicians (82%) reported seeing between one and five SMO per month, with patients being motivated by the need for additional information and reassurance. Physicians regarded SMO patients as having greater information needs (84%), greater psychosocial needs (58%) and requiring more of the physician's time and energy (77%) than other patients. SMOs are common in cancer care with most patients motivated by the need for improved communication, additional information and reassurance. Physicians identify patients who seek SMOs as having additional psychosocial needs compared with other oncology patients.

  12. Interaction of cis-[Ru(DMSO)4Cl2] with acetate-ion in solutions

    International Nuclear Information System (INIS)

    Buslaeva, T.M.; Rudnitskaya, O.V.; Kabanova, A.G.; Fedorova, G.A.

    2000-01-01

    Solutions of cis-[Ru(DMSO) 4 Cl 2 ] in water and alcohols in the presence of CH 3 COONa in dependence on concentration and relation of reagents are studied. It is shown that introduction of acetate-ion in solution of cis-[Ru(DMSO) 4 Cl 2 ] in methanol directs to formation of fac-[Ru(DMSO) 3 Cl 3 ] - which can be separated as sodium salt insoluble in methanol. It is necessary to mention that spectrum of solution of cis-[Ru(DMSO) 4 Cl 2 ] in methanol varies in time but these changes are insignificant in comparison with changes taking place in the presence of CH 3 COONa. Compound Na[Ru(DMSO) 3 (CH 3 COO) 2 Cl] is prepared and characterized spectrally for the first time [ru

  13. People's opinion of climate policy. Popular support for climate policy alternatives in Norway

    Energy Technology Data Exchange (ETDEWEB)

    Marino, Sjoevaag Marit; Bjoerge, Nils Erik; Ericson, Torgeir; Garnaasjordet, Per Arild; Karlsen, Haakon T.; Randers; Joergen; Rees, Daniel

    2012-07-01

    How can we evaluate whether national climate policies are sufficient? Which moral principles should be the basis of our policy efforts? The answers to these questions are central to the development of any climate policy framework, but not always made explicit in daily political discourse. In this article we seek to redress this imbalance through a survey of popular opinion in Norway.(Author)

  14. Embryonic exposure to cis-bifenthrin enantioselectively induces the transcription of genes related to oxidative stress, apoptosis and immunotoxicity in zebrafish (Danio rerio).

    Science.gov (United States)

    Jin, Yuanxiang; Pan, Xiuhong; Cao, Limin; Ma, Bufang; Fu, Zhengwei

    2013-02-01

    Cis-bifenthrin (cis-BF) is used widely for agricultural and non-agricultural purpose. Thus, cis-BF is one of the most frequently detected insecticides in the aquatic ecosystem. As a chiral pesticide, the commercial cis-BF contained two enantiomers including 1R-cis-BF and 1S-cis-BF. However, the difference in inducing oxidative stress, apoptosis and immunotoxicity by the two enantiomers in zebrafish still remains unclear. In the present study, the zebrafish were exposed to environmental concentrations of cis-BF, 1R-cis-BF and 1S-cis-BF during the embryos developmental stage. We observed that the mRNA levels of the most genes related to oxidative stress, apoptosis and immunotoxicity including Cu/Zn-superoxide dismutase (Cu/Zn-Sod), catalase (Cat), P53, murine double minute 2 (Mdm2), B-cell lymphoma/leukaemia-2 gene (Bcl2), Bcl2 associated X protein (Bax), apoptotic protease activating factor-1 (Apaf1), Caspase 9 (Cas9), Caspase 3 (Cas3), interleukin-1 beta (IL-1β) and interleukin-8(Il-8) were much higher in 1S-cis-BF treated group than those in cis-BF or 1R-cis-BF treated ones, suggesting that 1S-cis-BF has higher risk to induced oxidative stress, apoptosis and immunotoxicity than 1R-cis-BF in zebrafish. The information presented in this study will help with elucidating the differences and environmental risk of the two enantiomers of cis-BF-induced toxicity in aquatic organisms. Copyright © 2012 Elsevier Ltd. All rights reserved.

  15. Principals' Opinions on the Role of Speech-Language Pathologists Serving Students with Communication Disorders Involved in Violence

    Science.gov (United States)

    Ritzman, Mitzi J.; Sanger, Dixie

    2007-01-01

    Purpose: The purpose of this study was to survey the opinions of principals concerning the role of speech-language pathologists (SLPs) serving students with communication disorders who have been involved in violence. Method: A mixed methods design involving 678 questionnaires was mailed to elementary, middle, and high school principals in a…

  16. Opinions of legal professionals: Comparing child and adult witnesses' memory report capabilities

    Directory of Open Access Journals (Sweden)

    Jens Knutsson

    2014-07-01

    Full Text Available The opinions of legal professionals about child and adult witnesses might influence the likelihood that a case is allowed to proceed through the different stages of the legal process. With the aim of knowing the opinions of legal practitioners about child and adult witnesses, 84 legal professionals (Swedish police, prosecutors, and attorneys were surveyed about their beliefs about child and adult eyewitness memory (and metamemory abilities. The respondents answered 27 questions relating to nine forensically relevant belief areas in which they compared the memory ability of children (ages 7 to 11 years and adults. The results showed no differences in assessment among members of different professions and a general trend suggesting that, across the professions, children were believed to be poorer witnesses than adults regarding their memory abilities. Moreover, the professionals' within-group consensus was very low. These results are discussed in the context of eyewitness research findings and with respect to the implications for both legal and research practice.

  17. INVESTIGATION OF THE SOLVENT FREE ISOMERISATION OF cis ...

    African Journals Online (AJOL)

    Preferred Customer

    The rate of the solid state isomerisation of cis-Mo(CO)4(PPh3)2 was .... R = reflectance, k = absorption coefficient, s = scattering coefficient, c = concentration of the .... total loss of 75 % mass, which is assumed to be due to loss of the two PPh3 ...

  18. Stimulating energy conservation: the use of the opinion-leadership process

    Energy Technology Data Exchange (ETDEWEB)

    Yavas, U [Univ. of Petroleum and Minerals, Dhahran, Saudi Arabia; Riecken, G

    1981-09-01

    While the US federal government, public utilities and oil companies, among others, have instigated programs to educate the general public on energy conservation and to stimulate an energy-conservation ethic, results of a number of surveys indicate that such efforts in promoting energy conservation have had only limited success. This may be particularly attributable to the low credibility ascribed by the public to energy-information-disseminating sources. This article investigates the feasibility of utilizing opinion leadership, an untried approach, to overcome the credibility problem in disseminating energy information to the general public. 23 references, 4 tables.

  19. cis-4-[{sup 18}F]-Fluoro-L-proline fails to detect peripheral tumors in humans

    Energy Technology Data Exchange (ETDEWEB)

    Stoffels, Gabriele; Pauleit, Dirk [Institute of Neuroscience and Biophysics-Medicine, Research Centre Juelich, D-52425 Juelich, FRG (Germany); Haas, Rainer; Kobbe, Guido [Department of Oncology, Hematology, and Clinical Immunology, Heinrich-Heine-University Duesseldorf, FRG (Germany); Salber, Dagmar [C. and O. Vogt Institute of Brain Research, Heinrich-Heine-University Duesseldorf, FRG (Germany); Hamacher, Kurt; Coenen, Heinz H. [Institute of Neuroscience and Biophysics - Nuclear Chemistry, Research Centre Juelich, Juelich, FRG (Germany); Langen, Karl-Josef [Institute of Neuroscience and Biophysics-Medicine, Research Centre Juelich, D-52425 Juelich, FRG (Germany)], E-mail: k.j.langen@fz-juelich.de

    2008-11-15

    System A amino acid transport is increased in transformed and malignant cells. The amino acid 4-cis[{sup 18}F]fluoro-L-proline (cis-[{sup 18}F]FPro) has been shown to be a substrate of the System A amino acid carrier. In this pilot study, we investigated the diagnostic potential of cis-[{sup 18}F]FPro in patients with various tumors in comparison with [{sup 18}F]fluorodeoxyglucose-positron emission tomography (FDG-PET). Methods: Eight patients (seven females, one male, age range 43-77 years) with large primary, recurrent or metastatic tumors of different histologies were included in this study. One patient had a recurrent non-Hodgkin lymphoma; two patients, metastatic colon or rectal cancer; one, a metastatic endometrial cancer; one, a multiple myeloma; one, an Ewing sarcoma; one, a metastatic breast cancer and one, a gastrointestinal stromal tumor. PET scans of the trunk were acquired at 1 h after intravenous injection of 400 MBq cis-[{sup 18}F]FPro and compared to PET scans with [{sup 18}F]FDG. Results: None of the tumors or metastatic lesions in this series of patients demonstrated relevant uptake of cis-[{sup 18}F]FPro. In contrast, all tumors with exception of the multiple myeloma showed an intensive uptake of [{sup 18}F]FDG. The mean standardized uptake value of cis-[{sup 18}F]FPro in the tumor or metastases was significantly lower than that of [{sup 18}F]FDG uptake (1.7{+-}0.6 vs. 5.7{+-}3.0; n=8; P<.01). Conclusion: Although other System A-specific tracers have shown relevant tumor uptake, cis-[{sup 18}F]FPro fails to detect most types of human tumors. Based on these results, we cannot recommend a further evaluation of this tracer as a tumor-seeking agent.

  20. Extraction of metals such as Pu, U and Sr with an organic solvent or a solid phase containing a cis-syn-cis isomer of the crown ether DCH18C6

    International Nuclear Information System (INIS)

    Guy, A.; Foos, J.; Lemaire, M.; Guyon, V.; Chomel, R.; Doutreluigne, P.; Le Roy, H.

    1991-01-01

    The cis-syn-cis isomer of the crown ether DCH18C6 is used in solution in an organic diluent such as benzonitrile or dichlorethane, or on a solid phase such as silica. The use of this isomer increases the extraction ratio of plutonium and strontium of solution from spent fuel reprocessing or from aqueous effluents containing Sr or Pu [fr

  1. Determination of the valence-band offset of CdS/CIS solar cell devices by target factor analysis

    Energy Technology Data Exchange (ETDEWEB)

    Niles, D.W.; Contreras, M.; Ramanathan, K.; Noufi, R. [National Renewable Energy Lab., Golden, CO (United States)

    1996-05-01

    X-ray photoemission spectroscopy (XPS) is used to determine and compare the valence-band offsets ({Delta}E{sub v}) for CdS grown by chemical bath deposition on single-crystal and thin-film CuInSe{sub 2} (CIS). The thin-film CIS device was suitable for photovoltaic energy production. By sputtering through the CdS/CIS interface and reducing the depth profile with target factor analysis, the magnitude of {Delta}E{sub v} was determined to be {Delta}E{sub v} = 1.06 {+-} 0.15 eV for both the single-crystal and thin-film interfaces. This determination of {Delta}E{sub v} is about 0.25 eV larger than many previously reported estimations CdS grown by physical vapor deposition on CIS and helps explain the record performance of CdS/CIS photovoltaic devices.

  2. Study of biodistribution of lipidic nanospheres charged with cis-diaminedichloroplatinum (II) and labelled with radioactive nuclei of Indium-111; Estudio de biodistribucion de nanoesferas lipidicas cargadas con cis-diaminodicloroplatino (II) y marcadas con nucleos radioactivos de Indio-111

    Energy Technology Data Exchange (ETDEWEB)

    Lopez R, V.; Juarez O, C.; Medina L, A. [Unidad de Investigacion Biomedica en Cancer INCAN-UNAM, Mexico D.F. (Mexico); Perez C, E.; Garcia L, P. [Instituto nacional de cancerologia, Mexico D.F. (Mexico)

    2007-07-01

    The general objective of the study was to evaluate the lipidic nanospheres biodistribution charged with cis-diaminedichloroplatinum (II) (cis-DDP) and labelled with radioactive nuclei of Indium-111 (Lip-Cis-in-111) in Wistar rats and in a tumoral model of CaCu. The conclusions were: 1. The system Lip-Cis-in-111 it presents a very fast elimination probably, to a fast recognition response of the reticuloendothelial system (RES). 2. It is planned to make modifications to the formulation to increase the quantity of the hydrophilic polymer (PEG), so that its time of residence in the blood is bigger and allow a bigger accumulation in the tumor. (Author)

  3. Cis- and trans-perfluorodecalin: Infrared spectra, radiative efficiency and global warming potential

    Science.gov (United States)

    Le Bris, Karine; DeZeeuw, Jasmine; Godin, Paul J.; Strong, Kimberly

    2017-12-01

    Perfluorodecalin (PFD) is a molecule used in various medical applications for its capacity to dissolve gases. This potent greenhouse gas was detected for the first time in the atmosphere in 2005. We present infrared absorption cross-section spectra of a pure vapour of cis- and trans-perfluorodecalin at a resolution of 0.1 cm-1. Measurements were performed in the 560-3000 cm-1 spectral range using Fourier transform spectroscopy. The spectra have been compared with previous experimental data and theoretical calculations by density functional theory. The new experimental absorption cross-sections have been used to calculate a lifetime-corrected radiative efficiency at 300 K of 0.62 W m-2 ppb-1 and 0.57 W.m-2.ppb-1 for the cis and trans isomers respectively. This leads to a 100-year time horizon global warming potential of 8030 for cis-PFD and 7440 for trans-PFD.

  4. Managing the competitiveness in CIS countries and Ukraine: the goal and conditions

    Directory of Open Access Journals (Sweden)

    Anna KUKHARUK

    2017-06-01

    Full Text Available The study is focused on the analysis of conditions for business development and the industrial enterprises’ competitiveness formation in Commonwealth of Independent States (CIS. The study is based on several concepts – sustainable development, macroeconomic stability, “green economy”, and competitiveness. The article analyses the level of macroeconomic instability in a sample of CIS countries and Ukraine following the statistical approach and using the variation coefficient. The authors suggest calculating the indicators of stable development (SD-indicator and business simplicity (SB-indicator based on the international analytical reports data. Several CIS countries are visualized in SD and SB coordinates. The study defines the countries where the conditions for business competitiveness are to be improved due to the comparatively higher level of macroeconomic instability. The article will be interesting to scientists whose subject of research is the competitiveness of enterprises or the economic instability phenomena.

  5. OPINION GIVING SERVICES AS A SOURCE OF CONSUMER INFORMATION

    Directory of Open Access Journals (Sweden)

    Joanna Wyrwisz

    2015-09-01

    Full Text Available The goal of the article is to determine the place and role of opinion giving services in consumer behaviours. The discussion is conducted around the thesis saying that in the information society, opinion giving services constitute an important source of information for consumers in the process of selecting and purchasing both products and services. In the article the research approach based on the theoretical and empirical examinations was presented. The discussion starts with presenting a defi nition and types of opinion giving services which constitute the base for the characteristics of activities and usefulness of web portals collecting consumers opinions. The use of opinion giving services provided in the purchase process was evaluated. An essential interest in other consumers opinions, placed in Internet, was observed together with perceiving them as credible. Positive assessment of the functionality of opinion giving services was noticed.

  6. How are Voters Influenced by Opinion Polls? The Effect of Polls on Voting Behavior and Party Sympathy

    DEFF Research Database (Denmark)

    Dahlgaard, Jens Olav; Hansen, Jonas Hedegaard; Hansen, Kasper Møller

    2016-01-01

    Similar to all other types of information, public opinion polls can influence public opinion. We present two hypotheses to understand how polls affect public opinion: the bandwagon and the underdog effect. The bandwagon effect claims that voters "jump on the bandwagon," which means that if a party...... hypotheses. We find evidence of the bandwagon effect, and the effect is strongest in the positive direction. When voters learn that a party is gaining in the polls, voters will be more likely to vote for it. There is also some evidence for the negative bandwagon effect. We find no evidence for the underdog...... is gaining in the polls, the party will gain additional support from the voters, and vice versa if the party is losing in the polls. The underdog effect suggests that if a party is losing in the polls, the party will gain some sympathy votes to offset this loss. We use a survey experiment to test the two...

  7. Ancient and recent positive selection transformed opioid cis-regulation in humans.

    Directory of Open Access Journals (Sweden)

    Matthew V Rockman

    2005-12-01

    Full Text Available Changes in the cis-regulation of neural genes likely contributed to the evolution of our species' unique attributes, but evidence of a role for natural selection has been lacking. We found that positive natural selection altered the cis-regulation of human prodynorphin, the precursor molecule for a suite of endogenous opioids and neuropeptides with critical roles in regulating perception, behavior, and memory. Independent lines of phylogenetic and population genetic evidence support a history of selective sweeps driving the evolution of the human prodynorphin promoter. In experimental assays of chimpanzee-human hybrid promoters, the selected sequence increases transcriptional inducibility. The evidence for a change in the response of the brain's natural opioids to inductive stimuli points to potential human-specific characteristics favored during evolution. In addition, the pattern of linked nucleotide and microsatellite variation among and within modern human populations suggests that recent selection, subsequent to the fixation of the human-specific mutations and the peopling of the globe, has favored different prodynorphin cis-regulatory alleles in different parts of the world.

  8. Opinions from the front lines of cat colony management conflict.

    Directory of Open Access Journals (Sweden)

    M Nils Peterson

    Full Text Available Outdoor cats represent a global threat to terrestrial vertebrate conservation, but management has been rife with conflict due to differences in views of the problem and appropriate responses to it. To evaluate these differences we conducted a survey of opinions about outdoor cats and their management with two contrasting stakeholder groups, cat colony caretakers (CCCs and bird conservation professionals (BCPs across the United States. Group opinions were polarized, for both normative statements (CCCs supported treating feral cats as protected wildlife and using trap neuter and release [TNR] and BCPs supported treating feral cats as pests and using euthanasia and empirical statements. Opinions also were related to gender, age, and education, with females and older respondents being less likely than their counterparts to support treating feral cats as pests, and females being less likely than males to support euthanasia. Most CCCs held false beliefs about the impacts of feral cats on wildlife and the impacts of TNR (e.g., 9% believed feral cats harmed bird populations, 70% believed TNR eliminates cat colonies, and 18% disagreed with the statement that feral cats filled the role of native predators. Only 6% of CCCs believed feral cats carried diseases. To the extent the beliefs held by CCCs are rooted in lack of knowledge and mistrust, rather than denial of directly observable phenomenon, the conservation community can manage these conflicts more productively by bringing CCCs into the process of defining data collection methods, defining study/management locations, and identifying common goals related to caring for animals.

  9. Opinions from the Front Lines of Cat Colony Management Conflict

    Science.gov (United States)

    Peterson, M. Nils; Hartis, Brett; Rodriguez, Shari; Green, Matthew; Lepczyk, Christopher A.

    2012-01-01

    Outdoor cats represent a global threat to terrestrial vertebrate conservation, but management has been rife with conflict due to differences in views of the problem and appropriate responses to it. To evaluate these differences we conducted a survey of opinions about outdoor cats and their management with two contrasting stakeholder groups, cat colony caretakers (CCCs) and bird conservation professionals (BCPs) across the United States. Group opinions were polarized, for both normative statements (CCCs supported treating feral cats as protected wildlife and using trap neuter and release [TNR] and BCPs supported treating feral cats as pests and using euthanasia) and empirical statements. Opinions also were related to gender, age, and education, with females and older respondents being less likely than their counterparts to support treating feral cats as pests, and females being less likely than males to support euthanasia. Most CCCs held false beliefs about the impacts of feral cats on wildlife and the impacts of TNR (e.g., 9% believed feral cats harmed bird populations, 70% believed TNR eliminates cat colonies, and 18% disagreed with the statement that feral cats filled the role of native predators). Only 6% of CCCs believed feral cats carried diseases. To the extent the beliefs held by CCCs are rooted in lack of knowledge and mistrust, rather than denial of directly observable phenomenon, the conservation community can manage these conflicts more productively by bringing CCCs into the process of defining data collection methods, defining study/management locations, and identifying common goals related to caring for animals. PMID:22970269

  10. Opinions from the front lines of cat colony management conflict.

    Science.gov (United States)

    Peterson, M Nils; Hartis, Brett; Rodriguez, Shari; Green, Matthew; Lepczyk, Christopher A

    2012-01-01

    Outdoor cats represent a global threat to terrestrial vertebrate conservation, but management has been rife with conflict due to differences in views of the problem and appropriate responses to it. To evaluate these differences we conducted a survey of opinions about outdoor cats and their management with two contrasting stakeholder groups, cat colony caretakers (CCCs) and bird conservation professionals (BCPs) across the United States. Group opinions were polarized, for both normative statements (CCCs supported treating feral cats as protected wildlife and using trap neuter and release [TNR] and BCPs supported treating feral cats as pests and using euthanasia) and empirical statements. Opinions also were related to gender, age, and education, with females and older respondents being less likely than their counterparts to support treating feral cats as pests, and females being less likely than males to support euthanasia. Most CCCs held false beliefs about the impacts of feral cats on wildlife and the impacts of TNR (e.g., 9% believed feral cats harmed bird populations, 70% believed TNR eliminates cat colonies, and 18% disagreed with the statement that feral cats filled the role of native predators). Only 6% of CCCs believed feral cats carried diseases. To the extent the beliefs held by CCCs are rooted in lack of knowledge and mistrust, rather than denial of directly observable phenomenon, the conservation community can manage these conflicts more productively by bringing CCCs into the process of defining data collection methods, defining study/management locations, and identifying common goals related to caring for animals.

  11. 7 CFR 272.10 - ADP/CIS Model Plan.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false ADP/CIS Model Plan. 272.10 Section 272.10 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... benefit computation (including but not limited to all household members' names, addresses, dates of birth...

  12. Evolution of Cis-Regulatory Elements and Regulatory Networks in Duplicated Genes of Arabidopsis.

    Science.gov (United States)

    Arsovski, Andrej A; Pradinuk, Julian; Guo, Xu Qiu; Wang, Sishuo; Adams, Keith L

    2015-12-01

    Plant genomes contain large numbers of duplicated genes that contribute to the evolution of new functions. Following duplication, genes can exhibit divergence in their coding sequence and their expression patterns. Changes in the cis-regulatory element landscape can result in changes in gene expression patterns. High-throughput methods developed recently can identify potential cis-regulatory elements on a genome-wide scale. Here, we use a recent comprehensive data set of DNase I sequencing-identified cis-regulatory binding sites (footprints) at single-base-pair resolution to compare binding sites and network connectivity in duplicated gene pairs in Arabidopsis (Arabidopsis thaliana). We found that duplicated gene pairs vary greatly in their cis-regulatory element architecture, resulting in changes in regulatory network connectivity. Whole-genome duplicates (WGDs) have approximately twice as many footprints in their promoters left by potential regulatory proteins than do tandem duplicates (TDs). The WGDs have a greater average number of footprint differences between paralogs than TDs. The footprints, in turn, result in more regulatory network connections between WGDs and other genes, forming denser, more complex regulatory networks than shown by TDs. When comparing regulatory connections between duplicates, WGDs had more pairs in which the two genes are either partially or fully diverged in their network connections, but fewer genes with no network connections than the TDs. There is evidence of younger TDs and WGDs having fewer unique connections compared with older duplicates. This study provides insights into cis-regulatory element evolution and network divergence in duplicated genes. © 2015 American Society of Plant Biologists. All Rights Reserved.

  13. Which Characteristics of Gifted Students should be Developed? Student, Teacher and Parent Opinions

    Directory of Open Access Journals (Sweden)

    M. Serdar Köksal

    2017-06-01

    Full Text Available The aim of this research was to investigate parent, student and teacher opinions about which characteristics of gifted students should be developed in cognitive, affective, psychomotor and social learning areas. The participants included 609 gifted students, 350 parents and 157 teachers from Science and Art Canters. Participants were surveyed using “The Which Characteristics of Gifted Students Should Be Developed”. The results of research revealed that students, parents and teachers agreed that social and affective skills should be improved. On the other hand, they held different opinions on the importance of music, art, dance, role-play, sport, domestic economy skills. This result indicates that these skills are thought by participants to be less important for gifted students’ development. In addition, teachers did not think technology so important for the development of gifted students, placing more emphasis on cognitive and affective domains.

  14. Synthesis of 1-[13CD3]-9-cis-retinoic acid

    International Nuclear Information System (INIS)

    Bennani, Y.L.

    1995-01-01

    1-[ 13 CD 3 ]-9-cis-Retinoic acid was prepared in 8 steps from 2,6-dimethylcyclohexanone. Alkylation of 2,6-dimethylcyclohexanone under LiHMDS/MnBr 2 / 13 CD 3 I gave the corresponding labeled 2-[ 13 CD 3 ]-2,2,6-trimethylcyclohexanone 4 in good yield. Further functionalization of 4 to 6-[ 13 CD 3 ]-β-cyclocitral 6 proceeded through a Shapiro reaction. Aldehyde 6 was condensed with ethyl 3,3-dimethylacrylate to afford the corresponding bicyclic pyranone 7. Reduction of 7 to lactol 8, followed by acid-catalyzed ring opening gave the 9-cis-aldehyde 9. Wittig-Horner olefination and saponification afforded the title compound in good overall yield and in excellent isotopic purity. (Author)

  15. Identifying cis-regulatory modules by combining comparative and compositional analysis of DNA.

    Science.gov (United States)

    Pierstorff, Nora; Bergman, Casey M; Wiehe, Thomas

    2006-12-01

    Predicting cis-regulatory modules (CRMs) in higher eukaryotes is a challenging computational task. Commonly used methods to predict CRMs based on the signal of transcription factor binding sites (TFBS) are limited by prior information about transcription factor specificity. More general methods that bypass the reliance on TFBS models are needed for comprehensive CRM prediction. We have developed a method to predict CRMs called CisPlusFinder that identifies high density regions of perfect local ungapped sequences (PLUSs) based on multiple species conservation. By assuming that PLUSs contain core TFBS motifs that are locally overrepresented, the method attempts to capture the expected features of CRM structure and evolution. Applied to a benchmark dataset of CRMs involved in early Drosophila development, CisPlusFinder predicts more annotated CRMs than all other methods tested. Using the REDfly database, we find that some 'false positive' predictions in the benchmark dataset correspond to recently annotated CRMs. Our work demonstrates that CRM prediction methods that combine comparative genomic data with statistical properties of DNA may achieve reasonable performance when applied genome-wide in the absence of an a priori set of known TFBS motifs. The program CisPlusFinder can be downloaded at http://jakob.genetik.uni-koeln.de/bioinformatik/people/nora/nora.html. All software is licensed under the Lesser GNU Public License (LGPL).

  16. Ionizing radiation sources management in the Commonwealth of Independent States - CIS

    International Nuclear Information System (INIS)

    Iskra, A.; Bufetova, M.

    2006-01-01

    Ionizing radiation sources cover a broad band of power: from powerful NPP reactors and research reactors to portable radioisotope ionizing radiation sources applied in medicine, agriculture, industry and in the energy supply systems of remote facilities. At present, scales and use field of radionuclide sources in the CIS have the tendency to increase. In this connection, the issues of ionizing radiation sources management safety at all stages of their life cycle, from production to treatment, have been of a great importance. The materials on ionizing radiation sources inventory and treatment in the CIS (Russia, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Tajikistan and Ukraine) are presented in the report. It is shown that in some republics, there is difficulty in ionizing radiation sources accounting and control system; the national regulatory and legal framework bases regulating activity on radioactive sources use, localization and treatment require update. Many problems are connected with the sources beyond state accounting. The problem of ionizing radiation sources use safety is complicated by the growing activity of various terrorist groups. The opportunity to use ionizing radiation sources with terrorism goals requires the application of defined systems of security and physical protection at all stages of their management. For this purpose a collective, with all CIS countries, organization of radioactive sources accounting and control as well as countermeasures on their illegal transportation and use are necessary. In this connection, the information collection regarding situation with providing of ionizing radiation sources safety, conditions of equipment and storage facilities, radioactive materials accounting and control system in the CIS countries is vitally needed

  17. Thalassemia treatment and prevention in Uva Province, Sri Lanka: a public opinion survey.

    Science.gov (United States)

    Mudiyanse, Rasnayaka M

    2006-01-01

    -free marriages advocates promotion of marriages where at least one partner is a non-carrier. Success of such a project could be monitored at the time of marriage. This opinion survey indicates that the public is motivated to promote carrier screening and the prevention of thalassemia.

  18. THE LAWYER`S OPINION IN MODERN CIVIL LAW

    Directory of Open Access Journals (Sweden)

    Elena Evgenyevna Dubovaya

    2015-12-01

    Full Text Available Purpose to define value of freedom and fight of opinions, views and lawyer’s positions in development of science of civil law.Methodology theoretical analysis, inductive and deductive methods.Results It is established that fight of opinions, collision of various positions allows to understand more deeply the discussed problem, to come nearer to truth. So, free expression of opinions is the engine of development of civil law.Practical implications introduction in educational process on disciplines of civil jurisprudence, further research of fight of opinions in civil law.Tendencies of the present stage of development of legal system are characterized by aspiration to fix in the Russian legal system of the beginning of private law, where at the head of a corner – people as a legal entity. Opinions of lawyers on various legal problems, and the attitudes towards these opinions are subject to considerable dynamics. The centuries-old history of development of the right showed that fight of opinions, collision of various positions allows to understand more deeply the discussed problem, to come nearer to truth. The modern civil law widely uses a method of comparative jurisprudence, studying experience of the civilized countries which promoted in development of the civil legislation.

  19. Opinion Dynamics with Heterogeneous Interactions and Information Assimilation

    Science.gov (United States)

    Mir Tabatabaei, Seydeh Anahita

    2013-01-01

    In any modern society, individuals interact to form opinions on various topics, including economic, political, and social aspects. Opinions evolve as the result of the continuous exchange of information among individuals and of the assimilation of information distributed by media. The impact of individuals' opinions on each other forms a network,…

  20. Conciliatory and contradictory dynamics in opinion formation

    OpenAIRE

    Boudin , Laurent; Mercier , Aurore; Salvarani , Francesco

    2012-01-01

    International audience; In this article, we study, via a kinetic description, the effect of different psychologies on the evolution of the opinion with respect to a binary choice, in a closed group. We show that the interaction between individuals with different reactions regarding the exchange of opinion induces some phenomena, such as the concentration of opinions or the cyclic-in-time behaviour of the distribution function. We provide an existence and uniqueness result for the model and nu...

  1. Analysis and application of opinion model with multiple topic interactions.

    Science.gov (United States)

    Xiong, Fei; Liu, Yun; Wang, Liang; Wang, Ximeng

    2017-08-01

    To reveal heterogeneous behaviors of opinion evolution in different scenarios, we propose an opinion model with topic interactions. Individual opinions and topic features are represented by a multidimensional vector. We measure an agent's action towards a specific topic by the product of opinion and topic feature. When pairs of agents interact for a topic, their actions are introduced to opinion updates with bounded confidence. Simulation results show that a transition from a disordered state to a consensus state occurs at a critical point of the tolerance threshold, which depends on the opinion dimension. The critical point increases as the dimension of opinions increases. Multiple topics promote opinion interactions and lead to the formation of macroscopic opinion clusters. In addition, more topics accelerate the evolutionary process and weaken the effect of network topology. We use two sets of large-scale real data to evaluate the model, and the results prove its effectiveness in characterizing a real evolutionary process. Our model achieves high performance in individual action prediction and even outperforms state-of-the-art methods. Meanwhile, our model has much smaller computational complexity. This paper provides a demonstration for possible practical applications of theoretical opinion dynamics.

  2. Targeting cytokine signaling checkpoint CIS activates NK cells to protect from tumor initiation and metastasis

    Science.gov (United States)

    Putz, Eva M.; Guillerey, Camille; Kos, Kevin; Stannard, Kimberley; Miles, Kim; Delconte, Rebecca B.; Nicholson, Sandra E.; Huntington, Nicholas D.; Smyth, Mark J.

    2017-01-01

    ABSTRACT The cytokine-induced SH2-containing protein CIS belongs to the suppressor of cytokine signaling (SOCS) protein family. Here, we show the critical role of CIS in suppressing natural killer (NK) cell control of tumor initiation and metastasis. Cish-deficient mice were highly resistant to methylcholanthrene-induced sarcoma formation and protected from lung metastasis of B16F10 melanoma and RM-1 prostate carcinoma cells. In contrast, the growth of primary subcutaneous tumors, including those expressing the foreign antigen OVA, was unchanged in Cish-deficient mice. The combination of Cish deficiency and relevant targeted and immuno-therapies such as combined BRAF and MEK inhibitors, immune checkpoint blockade antibodies, IL-2 and type I interferon revealed further improved control of metastasis. The data clearly indicate that targeting CIS promotes NK cell antitumor functions and CIS holds great promise as a novel target in NK cell immunotherapy. PMID:28344878

  3. Rise of an alternative majority against opinion leaders

    Science.gov (United States)

    Tucci, K.; González-Avella, J. C.; Cosenza, M. G.

    2016-03-01

    We investigate the role of opinion leaders or influentials in the collective behavior of a social system. Opinion leaders are characterized by their unidirectional influence on other agents. We employ a model based on Axelrod's dynamics for cultural interaction among social agents that allows for non-interacting states. We find three collective phases in the space of parameters of the system, given by the fraction of opinion leaders and a quantity representing the number of available states: one ordered phase having the state imposed by the leaders; another nontrivial ordered phase consisting of a majority group in a state orthogonal or alternative to that of the opinion leaders, and a disordered phase, where many small groups coexist. We show that the spontaneous rise of an alternative group in the presence of opinion leaders depends on the existence of a minimum number of long-range connections in the underlying network. This phenomenon challenges the common idea that influentials are fundamental to propagation processes in society, such as the formation of public opinion.

  4. Assessment of online public opinions on large infrastructure projects: A case study of the Three Gorges Project in China

    International Nuclear Information System (INIS)

    Jiang, Hanchen; Qiang, Maoshan; Lin, Peng

    2016-01-01

    Public opinion becomes increasingly salient in the ex post evaluation stage of large infrastructure projects which have significant impacts to the environment and the society. However, traditional survey methods are inefficient in collection and assessment of the public opinion due to its large quantity and diversity. Recently, Social media platforms provide a rich data source for monitoring and assessing the public opinion on controversial infrastructure projects. This paper proposes an assessment framework to transform unstructured online public opinions on large infrastructure projects into sentimental and topical indicators for enhancing practices of ex post evaluation and public participation. The framework uses web crawlers to collect online comments related to a large infrastructure project and employs two natural language processing technologies, including sentiment analysis and topic modeling, with spatio-temporal analysis, to transform these comments into indicators for assessing online public opinion on the project. Based on the framework, we investigate the online public opinion of the Three Gorges Project on China's largest microblogging site, namely, Weibo. Assessment results present spatial-temporal distributions of post intensity and sentiment polarity, reveals major topics with different sentiments and summarizes managerial implications, for ex post evaluation of the world's largest hydropower project. The proposed assessment framework is expected to be widely applied as a methodological strategy to assess public opinion in the ex post evaluation stage of large infrastructure projects. - Highlights: • We developed a framework to assess online public opinion on large infrastructure projects with environmental impacts. • Indicators were built to assess post intensity, sentiment polarity and major topics of the public opinion. • We took the Three Gorges Project (TGP) as an example to demonstrate the effectiveness proposed framework.

  5. Assessment of online public opinions on large infrastructure projects: A case study of the Three Gorges Project in China

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Hanchen, E-mail: jhc13@mails.tsinghua.edu.cn; Qiang, Maoshan, E-mail: qiangms@tsinghua.edu.cn; Lin, Peng, E-mail: celinpe@mail.tsinghua.edu.cn

    2016-11-15

    Public opinion becomes increasingly salient in the ex post evaluation stage of large infrastructure projects which have significant impacts to the environment and the society. However, traditional survey methods are inefficient in collection and assessment of the public opinion due to its large quantity and diversity. Recently, Social media platforms provide a rich data source for monitoring and assessing the public opinion on controversial infrastructure projects. This paper proposes an assessment framework to transform unstructured online public opinions on large infrastructure projects into sentimental and topical indicators for enhancing practices of ex post evaluation and public participation. The framework uses web crawlers to collect online comments related to a large infrastructure project and employs two natural language processing technologies, including sentiment analysis and topic modeling, with spatio-temporal analysis, to transform these comments into indicators for assessing online public opinion on the project. Based on the framework, we investigate the online public opinion of the Three Gorges Project on China's largest microblogging site, namely, Weibo. Assessment results present spatial-temporal distributions of post intensity and sentiment polarity, reveals major topics with different sentiments and summarizes managerial implications, for ex post evaluation of the world's largest hydropower project. The proposed assessment framework is expected to be widely applied as a methodological strategy to assess public opinion in the ex post evaluation stage of large infrastructure projects. - Highlights: • We developed a framework to assess online public opinion on large infrastructure projects with environmental impacts. • Indicators were built to assess post intensity, sentiment polarity and major topics of the public opinion. • We took the Three Gorges Project (TGP) as an example to demonstrate the effectiveness proposed framework.

  6. Public opinion about large offshore wind power: Underlying factors

    International Nuclear Information System (INIS)

    Firestone, Jeremy; Kempton, Willett

    2007-01-01

    This paper address factors underlying public opinion regarding offshore wind power based on a survey of residents near a proposed development off Cape Cod, MA, USA. Supporters are found to be younger, better educated, and more likely to own their own home. Opponents are more likely to earn over $200,000/year, and more likely to expect to see the project from their daily routine. The overwhelming majority of the population expects negative impacts from the project; much smaller numbers expect positive effects. When asked which factors most affected their position, the most frequently mentioned was damage to marine life/environmental impacts, followed by electricity rates, aesthetics, and impacts on fishing or boating. When the expectations expressed by our respondents are compared with the findings of the project's draft Environmental Impact Statement, many of the beliefs upon which opinion are based appear to be factually incorrect. Finally, we tested whether change in the project would affect support. The biggest change was an increase in the level of support, by 47% of the sample, if the project was the first of 300 such projects, in sum having proportionately larger impacts as well as greater benefits. Implications of this research are discussed

  7. A survey of contemporary opinions and practices of surgical and intensive care specialists towards peri-operative venous thromboembolism prophylaxis in Asia.

    Science.gov (United States)

    Lee, L; Liew, N C; Gee, T

    2012-12-01

    This survey was conducted to determine the opinions and practices of peri-operative venous thromboembolism (VTE) prophylaxis among surgical and intensive care specialists in Asia. A set of questionnaire was distributed to surgeons and intensivists from different countries in Asia. The specialties included were general surgery and its sub-specialties, orthopaedic surgery, gynaecological surgery and intensive care unit. This survey involved teaching institutions, general hospitals and private hospitals. To gauge if the respondents were from hospitals that would likely encounter VTE cases, the hospital's bed-strength, intensive care facility and sub-specialty services were recorded. Over a period of six months, questionnaires and feedbacks were collected and analyzed. One hundred and ninety-one responses were received from 8 countries throughout Asia. Fifty-six percent of these were from large hospitals (800 bedded or more) and 62% of these hospitals have large intensive care facility (20 or more beds). Only half of the respondents practice routine thromboprophylaxis in moderate and high risk surgeries. Thirty six percent of them practices selective thromboprophylaxis and only 3% do not believe in any thromboprophylaxis. A third prescribed thromboprophylaxis for 3 to 5 days; another third extended it until patient is mobile. About 48.6% of the respondents do not have VTE guidelines in their institutions. Majority of the respondents agreed that more evidence is needed in the form of multi-centre randomized controlled trials to influence their decision on thromboprophylaxis. Despite the availability of strong epidemiological data, randomized controlled trials and multicentre case-controlled studies, perioperative VTE prophylactic practices are still suboptimal in Asia.

  8. Oil industry perspective on investment: in the CIS/Russia

    International Nuclear Information System (INIS)

    Boulos, A.J.

    1994-01-01

    Despite the existance of abundant petroleum reserves in the CIS, oil production is decreasing through lack of sophisticated equipment, advanced technology and capital to fully exploit existing and now depleting oil fields and to open up new ones. The oil industry is in need of restructuring and substantial investment if it is to meet increasing domestic demand. Positive moves are being made within the CIS to create an attractive investment climate and encourage the setting up of joint ventures with foreign companies. The types of joint venture agreements that could be used are examined and the challenges and opportunities provided by such ventures are discussed. Notwithstanding serious problems, particularly those relating to political stability and the creation of a suitable legal framework, it is concluded that significant and promising opportunities exist for joint ventures in the oil and gas sectors. (UK)

  9. Effects of Groups’ Spatial Segregation on Processes of Opinion Polarization

    NARCIS (Netherlands)

    Feliciani, Thomas; Flache, Andreas

    2015-01-01

    We contribute to the literature about processes of opinion formation, investigating theoretically how the spatial segregation of two groups affects opinion polarization as a possible outcome of opinion formation. We focus on two processes of opinion polarization (negative influence and persuasive

  10. EU-CIS joint study project 2. Intervention criteria in CIS, risk assessments and non-radiological factors in decision-making

    Energy Technology Data Exchange (ETDEWEB)

    Hedemann Jensen, P. [Risoe National Lab., Roskilde (Denmark); Demin, V.F. [Russian Reserch Centre `Kurchatov Inst.`, Moscow (Russian Federation); Konstantinov, Y.O. [Research Inst. of Radiation Hygiene, St. Petersburg (Russian Federation); Likhtarev, I.A. [Ukrainian Scientific Centre for Radiation Medicine, Kiev (Ukraine); Rolevich, I.V. [Chernobyl State Commiettee, Minsk (Belarus); Schneider, T. [Centre d`etudes sur l`Evaluation de la Protection dans le domaine Nucleaire, CEPN, Paris (France)

    1996-05-01

    An extensive radiation risk estimation methodology has recently been developed in Russia and used for estimates of risk in exposed populations in the republics of Russia, Belarus and Ukraine. Results based on demographic data for the three republics are presented and compared with risk estimates from the EU risk model ASQRAD. The intervention criteria in the CIS republics have been evolving since the Chernobyl accident. The development of criteria in each of the three republics has been analysed and the CIS-Criteria have been compared to international guidance on intervention. After a nuclear or radiological emergency both radiological and non-radiological protection factors will influence the level of protective actions being introduced. The role of non-radiological protection factors in the overall optimization of health protection is addressed. It is argued that optimization of the overall health protection is not a question of developing radiation radiation protection philosophy to fully include socio-psychological factors. It is rather a question of including these factors - in parallel with the radiological protection factors - in cooperation between radiation protection experts and psychological specialists under the responsibility of the decision maker. (au) 19 tabs., 10 ills., 45 refs.

  11. EU-CIS joint study project 2. Intervention criteria in CIS, risk assessments and non-radiological factors in decision-making

    International Nuclear Information System (INIS)

    Hedemann Jensen, P.; Demin, V.F.; Konstantinov, Y.O.; Likhtarev, I.A.; Rolevich, I.V.; Schneider, T.

    1996-05-01

    An extensive radiation risk estimation methodology has recently been developed in Russia and used for estimates of risk in exposed populations in the republics of Russia, Belarus and Ukraine. Results based on demographic data for the three republics are presented and compared with risk estimates from the EU risk model ASQRAD. The intervention criteria in the CIS republics have been evolving since the Chernobyl accident. The development of criteria in each of the three republics has been analysed and the CIS-Criteria have been compared to international guidance on intervention. After a nuclear or radiological emergency both radiological and non-radiological protection factors will influence the level of protective actions being introduced. The role of non-radiological protection factors in the overall optimization of health protection is addressed. It is argued that optimization of the overall health protection is not a question of developing radiation radiation protection philosophy to fully include socio-psychological factors. It is rather a question of including these factors - in parallel with the radiological protection factors - in cooperation between radiation protection experts and psychological specialists under the responsibility of the decision maker. (au) 19 tabs., 10 ills., 45 refs

  12. Opinions of traveling agencies’ managers regarding the traveling behavior of people from Braşov

    Directory of Open Access Journals (Sweden)

    Untaru, E.

    2010-12-01

    Full Text Available The adaptation of tourism businesses to the needs of the consumers they address to by means of their offer cannot be achieved without in-depth knowledge of consumer and purchase behaviour. Acknowledgement of consumer behaviour involves identifying, anticipating and meeting consumers’ needs in a profitable manner. This article represents a qualitative survey conducted by the semi-directive in-depth interview method among travel agencies in the city of Braşov, with the purpose of revealing managers' views regarding the opinions of people in Braşov towards tourist trips. The results of the qualitative research will form the starting point in the achievement of a quantitative research among people in Braşov, with focus on their opinions, attitudes and behaviours towards travelling, in general.

  13. Cis-, intra-, subgenesis, genome editing as modern technologies for modifying the crop genomes (review

    Directory of Open Access Journals (Sweden)

    Н. Е. Волкова

    2016-02-01

    Full Text Available Purpose. Reviewing the literature on modern technologies of genetic modification of crop genomes. Results. The current state of genetically modified plants creation is analyzed. The information on cis-, intra- and subgenic plants and their comparison with transgenic crops is given. Examples of cis- and intragenesis application for improving characteristics of crops are provided. Such state-of-the-art technology of crop genome modification as genome editing is considered. Conclusions. Technologies for producing cis-, intra-, subgenic plants are rapidly developing and resulting in crops of the 21st century that can solve the problem of food provision for a constantly growing world population with the least contrary to the public interest.

  14. An in vivo comparison of cis- and trans-[{sup 18}F]mefway in the nonhuman primate

    Energy Technology Data Exchange (ETDEWEB)

    Wooten, Dustin, E-mail: dwooten@wisc.edu [Department of Medical Physics, Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin-Madison, Madison, WI 53705 (United States); Hillmer, Ansel; Murali, Dhanabalan; Barnhart, Todd [Department of Medical Physics, Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin-Madison, Madison, WI 53705 (United States); Schneider, Mary L. [Department of Kinesiology, University of Wisconsin-Madison, Madison, WI 53706 (United States); Mukherjee, Jogeshwar [Preclinical Imaging Center, Department of Psychiatry and Human Behavior, University of California-Irvine, Irvine 92697 (United States); Christian, Bradley T. [Department of Medical Physics, Waisman Laboratory for Brain Imaging and Behavior, University of Wisconsin-Madison, Madison, WI 53705 (United States)

    2011-10-15

    Introduction: [{sup 18}F]Mefway is a serotonin 5-HT{sub 1A} PET radiotracer with high specificity and favorable in vivo imaging properties. The chemical structure of [{sup 18}F]mefway permits {sup 18}F labeling in either the cis or trans positions at the 4-cyclohexyl site. We have previously reported on the in vivo kinetics of trans-[{sup 18}F]mefway in the nonhuman primate. In this work, we compare the in vivo binding of cis-[{sup 18}F]mefway and trans-[{sup 18}F]mefway to evaluate the properties of cis-[{sup 18}F]mefway for 5-HT{sub 1A} PET imaging. Methods: The cis- and trans-[{sup 18}F]mefway tracers were synthesized via nucleophilic substitution with their respective tosyl precursors. Two monkeys (one male, one female) were given bolus injections of both cis- and trans-labeled [{sup 18}F]mefway in separate experiments. Dynamic scans were acquired for 90 min with a microPET P4 scanner. Time-activity curves were extracted in the areas of the mesial temporal cortex (MTC), anterior cingulate gyrus (aCG), insular cortex (IC), raphe nuclei (RN) and cerebellum (CB). The in vivo behavior of the radiotracers was compared based upon the nondisplaceable binding potential (BP{sub ND}) using the CB as a reference region. Results: Averaged over the two subjects, BP{sub ND} values were as follows: MTC: 7.7, 0.58; aCG: 4.95, 0.32; IC: 3.27, 0.2; and RN: 3.05, 0.13, for trans-[{sup 18}F]mefway and cis-[{sup 18}F]mefway, respectively. Conclusion: The cis-labeled [{sup 18}F]mefway tracer has low specific binding throughout the 5-HT{sub 1A} regions of the brain compared to trans-[{sup 18}F]mefway, suggesting that the target-to-background binding of cis-[{sup 18}F]mefway may limit its use for in vivo assessment of 5-HT{sub 1A} binding.

  15. Reliability Analysis of Public Survey in Satisfaction with Nuclear Safety

    International Nuclear Information System (INIS)

    Park, Moon Soo; Moon, Joo Hyun; Kang, Chang Sun

    2005-01-01

    Korea Institute of Nuclear Safety (KINS) carried out a questionnaire survey on public's understanding nuclear safety and regulation in order to grasp public acceptance for nuclear energy. The survey was planned to help to analyze public opinion on nuclear energy and provide basic data for advertising strategy and policy development. In this study, based on results of the survey, the reliability of the survey was evaluated according to each nuclear site

  16. Structural Elucidation of cis / trans Dicaffeoylquinic Acid Photoisomerization Using Ion Mobility Spectrometry-Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Xueyun; Renslow, Ryan S.; Makola, Mpho M.; Webb, Ian K.; Deng, Liulin; Thomas, Dennis G.; Govind, Niranjan; Ibrahim, Yehia M.; Kabanda, Mwadham M.; Dubery, Ian A.; Heyman, Heino M.; Smith, Richard D.; Madala, Ntakadzeni E.; Baker, Erin S.

    2017-03-15

    Due to the recently uncovered health benefits and anti-HIV activities of dicaffeoylquinic acids (diCQAs), understanding their structures and functions is of great interest for drug discovery efforts. DiCQAs are analytically challenging to identify and quantify since they commonly exist as a diverse mixture of positional and geometric (cis/trans) isomers. In this work, we utilized ion mobility spectrometry coupled with mass spectrometry to separate the various isomers before and after UV irradiation. The experimental collision cross sections were then compared with theoretical structures to differentiate and identify the diCQA isomers. Our analyses found that naturally the diCQAs existed predominantly as trans/trans isomers, but after 3 h of UV irradiation, cis/cis, cis/trans, trans/cis, and trans/trans isomers were all present in the mixture. This is the first report of successful differentiation of cis/trans diCQA isomers individually, which shows the great promise of IMS coupled with theoretical calculations for determining the structure and activity relationships of different isomers in drug discovery studies.

  17. 9-cis-retinoic acid increases apolipoprotein AI secretion and mRNA expression in HepG2 cells.

    Science.gov (United States)

    Haghpassand, M; Moberly, J B

    1995-10-01

    HepG2 cells were studied as a model for regulation of hepatic apolipoprotein AI (apo AI) secretion and gene expression by 9-cis-retinoic acid. HepG2 cells cultured on plastic dishes were exposed to 9-cis-retinoic acid (9-cis-RA) for 48 h with a complete media change at 24 h. Apo AI mass in cultured media was determined by ELISA, by quantitative immunoblotting and by steady-state 35S-methionine labeling. Messenger RNA levels were determined by RNase protection using probes for apo AI and the housekeeping gene, glyceraldehyde 3-phosphate dehydrogenase (G3PDH). 9-cis-RA increased secretion of apo AI by 52% at doses of 10 and 1 microM (6.3 +/- 0.6 vs. 4.2 +/- 0.3; P G3PDH mRNA was slightly decreased (14%, P < 0.05). Thus, 9-cis-RA stimulates apo AI expression in HepG2 cells, suggesting a role for retinoids in activating endogenous apo AI gene expression.

  18. The effect of case-based discussion of topics with experts on learners' opinions: implications for spinal education and training.

    Science.gov (United States)

    Berjano, Pedro; Villafañe, Jorge Hugo; Vanacker, Gerard; Cecchinato, Riccardo; Ismael, Maryem; Gunzburg, Robert; Marruzzo, Daniele; Lamartina, Claudio

    2017-10-01

    This investigation aimed to examine the extent to which case-based discussion with experts could influence the audience's opinions on the treatment of patients during a continuing medical education event for spine surgeons. We conducted a prospective controlled crossover study of 90 surgeons. During a continuing medical education activity using case-based discussion, quiz questions were used which asked participants (attendants and faculty group) their opinions on the best choices about diagnosis and treatment in a number of cases. No answer was considered correct, but we evaluated the number of participants choosing each specific answer among a number of valid options. Quiz questions were collected with an automated response system at the entry and at the end of each case discussion. Change in participant's opinions was estimated from the change in the preferred answers between the entry and exit quizzes. Chi-square analysis was performed to determine significance. Sixty-two attendants out of eighty three (75%) and six faculties out of twelve (50%) responded to the survey. After the case discussion, 68.2% (p < 0.04, Chi-square test) of the attendants changed their opinion on the appropriate treatment. The faculty answers, however, showed no significant change in opinions regarding the identification of the appropriate treatment. On the basis of our results, case-based discussion driven by experts, as a form of teaching, has a measurable effect in terms of changes in the learners' opinions.

  19. Identifying deficiencies in national and foreign medical team responses through expert opinion surveys: implications for education and training.

    Science.gov (United States)

    Djalali, Ahmadreza; Ingrassia, Pier Luigi; Corte, Francesco Della; Foletti, Marco; Gallardo, Alba Ripoll; Ragazzoni, Luca; Kaptan, Kubilay; Lupescu, Olivera; Arculeo, Chris; von Arnim, Gotz; Friedl, Tom; Ashkenazi, Michael; Heselmann, Deike; Hreckovski, Boris; Khorram-Manesh, Amir; Khorrram-Manesh, Amir; Komadina, Radko; Lechner, Kostanze; Patru, Cristina; Burkle, Frederick M; Fisher, Philipp

    2014-08-01

    Unacceptable practices in the delivery of international medical assistance are reported after every major international disaster; this raises concerns about the clinical competence and practice of some foreign medical teams (FMTs). The aim of this study is to explore and analyze the opinions of disaster management experts about potential deficiencies in the art and science of national and FMTs during disasters and the impact these opinions might have on competency-based education and training. This qualitative study was performed in 2013. A questionnaire-based evaluation of experts' opinions and experiences in responding to disasters was conducted. The selection of the experts was done using the purposeful sampling method, and the sample size was considered by data saturation. Content analysis was used to explore the implications of the data. This study shows that there is a lack of competency-based training for disaster responders. Developing and performing standardized training courses is influenced by shortcomings in budget, expertise, and standards. There is a lack of both coordination and integration among teams and their activities during disasters. The participants of this study emphasized problems concerning access to relevant resources during disasters. The major findings of this study suggest that teams often are not competent during the response phase because of education and training deficiencies. Foreign medical teams and medically related nongovernmental organizations (NGOs) do not always provide expected capabilities and services. Failures in leadership and in coordination among teams are also a problem. All deficiencies need to be applied to competency-based curricula.

  20. A single cis element maintains repression of the key developmental regulator Gata2.

    Directory of Open Access Journals (Sweden)

    Jonathan W Snow

    2010-09-01

    Full Text Available In development, lineage-restricted transcription factors simultaneously promote differentiation while repressing alternative fates. Molecular dissection of this process has been challenging as transcription factor loci are regulated by many trans-acting factors functioning through dispersed cis elements. It is not understood whether these elements function collectively to confer transcriptional regulation, or individually to control specific aspects of activation or repression, such as initiation versus maintenance. Here, we have analyzed cis element regulation of the critical hematopoietic factor Gata2, which is expressed in early precursors and repressed as GATA-1 levels rise during terminal differentiation. We engineered mice lacking a single cis element -1.8 kb upstream of the Gata2 transcriptional start site. Although Gata2 is normally repressed in late-stage erythroblasts, the -1.8 kb mutation unexpectedly resulted in reactivated Gata2 transcription, blocked differentiation, and an aberrant lineage-specific gene expression pattern. Our findings demonstrate that the -1.8 kb site selectively maintains repression, confers a specific histone modification pattern and expels RNA Polymerase II from the locus. These studies reveal how an individual cis element establishes a normal developmental program via regulating specific steps in the mechanism by which a critical transcription factor is repressed.

  1. On the opinion formation of mobile agents with memory

    Science.gov (United States)

    Zhang, Yunhong; Liu, Qipeng; Wang, Zhenling; Zhang, Siying

    2018-02-01

    This paper studies the opinion formation problem in a group of mobile agents using a multi-agent modeling method. Suppose that all agents move in a two-dimensional space following a certain rule. The interaction range of each agent is determined by its physical location and its opinion similarity with other agents. Moreover, agents have memory of the opinions of their previous interactive neighbors. We investigate the influence of three factors on the formation of group opinion: moving probability, interactive radius, and population density. Using simulations, we find that an opinion consensus can be achieved easily under a small moving probability and a small interactive radius, which is a relatively counterintuitive phenomenon. We also find that a large interactive radius or the model with memory can facilitate the convergence of opinions in a group to either consensus or clusters.

  2. Democracy, public opinion, and nuclear weapons

    International Nuclear Information System (INIS)

    Russett, B.

    1989-01-01

    To the degree that people's fears of nuclear war are deep and pervasive, they become subject to manipulation by cynical or politically utopian promises, whether those promises be to abolish nuclear weapons from the earth or to create a leakproof peace shield (SDI). But the basic yearning for protection could also be mobilized to support serious arms reduction and arms control agreements. Nuclear weapons provide the basis for a vivid form of symbolic politics, perhaps equivalent in foreign policy considerations to the Korean and Vietnam wars during their durations, and in similar ways (although not necessarily as severe) as unemployment does among domestic policy issues. This paper presents survey research directed specifically at the role of public opinion on nuclear imagery (difference between expectation of nuclear war versus any kind of weapon war; willingness to spend on nuclear weapons versus conventional ones or general defense spending) can help in understanding these phenomena

  3. College Students Opinions on Gun Violence.

    Science.gov (United States)

    Lewis, Rhonda K; LoCurto, Jamie; Brown, Kyrah; Stowell, David; Maryman, J'Vonnah; Dean, Amber; McNair, Thoi; Ojeda, Debbie; Siwierka, Julia

    2016-06-01

    Gun violence and control issues have become serious public health problems. This study gathered the opinions from 419 college students from a Midwestern University. Participants were asked about beliefs about purchasing assault weapons, beliefs about bringing handguns to college campuses and beliefs about contributing factors that lead to gun violence. Participants completed surveys online. The findings showed that overall 54 % of respondents believed that military assault weapons should be banned and 53 % agree that teachers should be allowed to carry a registered handgun on campus. There were statistically significant differences between males and females on these issues. For instance, females believed military assault weapons and high capacity magazines should be banned more than 1.9 times (p = .004) p gun violence were decline in parenting and family values (17 %), gang involvement (14 %), bullying (13.8 %) and guns being easy to obtain (13.8 %). Limitations and implications for policy work are discussed.

  4. Cis-Natural Antisense Transcripts Are Mainly Co-expressed with Their Sense Transcripts and Primarily Related to Energy Metabolic Pathways during Muscle Development.

    Science.gov (United States)

    Zhao, Yunxia; Hou, Ye; Zhao, Changzhi; Liu, Fei; Luan, Yu; Jing, Lu; Li, Xinyun; Zhu, Mengjin; Zhao, Shuhong

    2016-01-01

    Cis-natural antisense transcripts (cis-NATs) are a new class of RNAs identified in various species. However, the biological functions of cis-NATs are largely unknown. In this study, we investigated the transcriptional characteristics and functions of cis-NATs in the muscle tissue of lean Landrace and indigenous fatty Lantang pigs. In total, 3,306 cis-NATs of 2,469 annotated genes were identified in the muscle tissue of pigs. More than 1,300 cis-NATs correlated with their sense genes at the transcriptional level, and approximately 80% of them were co-expressed in the two breeds. Furthermore, over 1,200 differentially expressed cis-NATs were identified during muscle development. Function annotation showed that the cis-NATs participated in muscle development mainly by co-expressing with genes involved in energy metabolic pathways, including citrate cycle (TCA cycle), glycolysis or gluconeogenesis, mitochondrial activation and so on. Moreover, these cis-NATs and their sense genes abruptly increased at the transition from the late fetal stages to the early postnatal stages and then decreased along with muscle development. In conclusion, the cis-NATs in the muscle tissue of pigs were identified and determined to be mainly co-expressed with their sense genes. The co-expressed cis-NATs and their sense gene were primarily related to energy metabolic pathways during muscle development in pigs. Our results offered novel evidence on the roles of cis-NATs during the muscle development of pigs.

  5. Topological evolution of the internet public opinion

    Science.gov (United States)

    Lian, Ying; Dong, Xuefan; Liu, Yijun

    2017-11-01

    The Internet forms a platform featured with high liquidity, accessibility and concealment for the public to express their respective views on certain events, thus leading to a large network graph. Due to such environmental features, the public opinions formed on the Internet are different from those on traditional media. Studies focusing on the former area are relatively fewer. In addition, the majority of existing methods proposed for constructing the Internet public opinion topological structure are based on the classic BA model, thus resulting in drawbacks in the range of simplicity and a lack of strict deduction. Therefore, based on the complex networks theory, a model applied to describe the topology of the Internet public opinion is deduced with rigorous derivation in the present paper. Results show that the proposed expression could well reflect the degree distribution of Internet public opinion which follows an analogous power law distribution, and that the peak value and the degree distribution are not correlative to each other. Moreover, it has been also proved that compared to the classic BA model, the proposed model has better accuracy performance in the description of the degree distribution of the Internet public opinion, which contributes to future studies focusing on this area. Thus, an attempt has been made to give the first theoretical description of the Internet public opinion topology in the present paper. In addition, it is also the first paper focusing on the solution of networks degree distribution with an exponential growth form.

  6. Parents' knowledge of and opinions about healthcare laws and technology in primary care.

    Science.gov (United States)

    Thompson, Lindsay A; Black, Erik W; Saliba, Heidi; Schentrup, Anzeela M

    2012-01-01

    Historically, parents have demonstrated poor understanding of adolescent healthcare laws. This study assessed US parents' current knowledge and opinions about technology facilitated physician-adolescent communication and applicable laws to enhance transition to adult health care. A brief survey in two low-income academic paediatric clinics asked parents about their knowledge of health care and laws, and their opinions about technology facilitated contact between physicians and adolescents. Almost all parents (96.7%) have internet access at home, work or via a mobile device. Only 44.1% approved of having a physician directly contact their child about annual examinations, immunisations or to discuss issues of sexuality. Half (55.4%) were aware that adolescents could receive confidential sexuality information and treatment without parents' permission. Only one-third (32.2%) approved of a specific technology for direct communication. Parents are divided about direct physician-adolescent contact. Future plans to engage adolescents to understand their health will require parental education and involvement on the value of physician-adolescent communication.

  7. Objectification of injuries and consequences in expert medical opinions

    Directory of Open Access Journals (Sweden)

    Miran Vrabl

    2007-04-01

    Full Text Available Background: Only unequivocal evidence confirming the total extent of injury. Biomechanical analysis, objectifications of permanent consequences after injury and objectification, whether such injuries influence life activities of an injured person, should be the basics for preparation of expert medical opinion. To make a necessary distinction from the previous injuries or illnesses that might have influence on current health state of a patient and its treatment, analysis of all medical records of a certain injured person is needed. Therefore this are inevitable steps in preparation of an expert medical opinion. In cases when medical opinion should explain disability of a patient as a consequence of a certain contractual relationship, the contract should be taken into consideration when such opinions is prepared.Methods: 500 opinions have been retrospectively analysed, selected at random out of 3452 opinions, submitted in claims for damages at Zavarovalnica Maribor, d. d., in the period from January 2001 until January 2006. Thirteen typical data have been analysed and evaluated on the basis of objective evidences.Results: On the basis of analyses it has been established that there is a great difference between principles of objectification and the data in analysed opinions. It has been noticed the most obvious deviation in biomechanical analysis (95 %, in records of decreased life activities (90 %, in all medical records of an injured person (65 % and in objectification of permanent consequences after injuries (55 %.Conclusions: As results of analysis demonstrate, there are significant differences in preparations of expert and medical opinions in Slovenia, particularly when basic principles are analysed that need to be considered when writing such opinions. Irrational avoidance of basic principle of objectification, nomination of experts without licence in certain fields of medicine, avoidance of objectification of subjective statements of injured

  8. Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis.

    Science.gov (United States)

    Yang, Fan; Wang, Jiebiao; Pierce, Brandon L; Chen, Lin S

    2017-11-01

    The impact of inherited genetic variation on gene expression in humans is well-established. The majority of known expression quantitative trait loci (eQTLs) impact expression of local genes ( cis -eQTLs). More research is needed to identify effects of genetic variation on distant genes ( trans -eQTLs) and understand their biological mechanisms. One common trans -eQTLs mechanism is "mediation" by a local ( cis ) transcript. Thus, mediation analysis can be applied to genome-wide SNP and expression data in order to identify transcripts that are " cis -mediators" of trans -eQTLs, including those " cis -hubs" involved in regulation of many trans -genes. Identifying such mediators helps us understand regulatory networks and suggests biological mechanisms underlying trans -eQTLs, both of which are relevant for understanding susceptibility to complex diseases. The multitissue expression data from the Genotype-Tissue Expression (GTEx) program provides a unique opportunity to study cis -mediation across human tissue types. However, the presence of complex hidden confounding effects in biological systems can make mediation analyses challenging and prone to confounding bias, particularly when conducted among diverse samples. To address this problem, we propose a new method: Genomic Mediation analysis with Adaptive Confounding adjustment (GMAC). It enables the search of a very large pool of variables, and adaptively selects potential confounding variables for each mediation test. Analyses of simulated data and GTEx data demonstrate that the adaptive selection of confounders by GMAC improves the power and precision of mediation analysis. Application of GMAC to GTEx data provides new insights into the observed patterns of cis -hubs and trans -eQTL regulation across tissue types. © 2017 Yang et al.; Published by Cold Spring Harbor Laboratory Press.

  9. cultural variations regarding the nature and determinants of opinion ...

    African Journals Online (AJOL)

    p2333147

    Keywords: Opinion leaders, cultural influence, diffusion and determinants of opinion leadership. ABSTRACT. This paper compares the findings from different countries regarding the nature and determinants of opinion leadership. ..... agricultural production among male and female farmers of the Kusenge. Parish in the ...

  10. Social influence and the collective dynamics of opinion formation.

    Science.gov (United States)

    Moussaïd, Mehdi; Kämmer, Juliane E; Analytis, Pantelis P; Neth, Hansjörg

    2013-01-01

    Social influence is the process by which individuals adapt their opinion, revise their beliefs, or change their behavior as a result of social interactions with other people. In our strongly interconnected society, social influence plays a prominent role in many self-organized phenomena such as herding in cultural markets, the spread of ideas and innovations, and the amplification of fears during epidemics. Yet, the mechanisms of opinion formation remain poorly understood, and existing physics-based models lack systematic empirical validation. Here, we report two controlled experiments showing how participants answering factual questions revise their initial judgments after being exposed to the opinion and confidence level of others. Based on the observation of 59 experimental subjects exposed to peer-opinion for 15 different items, we draw an influence map that describes the strength of peer influence during interactions. A simple process model derived from our observations demonstrates how opinions in a group of interacting people can converge or split over repeated interactions. In particular, we identify two major attractors of opinion: (i) the expert effect, induced by the presence of a highly confident individual in the group, and (ii) the majority effect, caused by the presence of a critical mass of laypeople sharing similar opinions. Additional simulations reveal the existence of a tipping point at which one attractor will dominate over the other, driving collective opinion in a given direction. These findings have implications for understanding the mechanisms of public opinion formation and managing conflicting situations in which self-confident and better informed minorities challenge the views of a large uninformed majority.

  11. Reliability Analysis of Public Survey in Satisfaction with Nuclear Safety

    Energy Technology Data Exchange (ETDEWEB)

    Park, Moon Soo; Moon, Joo Hyun; Kang, Chang Sun [Seoul National Univ., Seoul (Korea, Republic of)

    2005-07-01

    Korea Institute of Nuclear Safety (KINS) carried out a questionnaire survey on public's understanding nuclear safety and regulation in order to grasp public acceptance for nuclear energy. The survey was planned to help to analyze public opinion on nuclear energy and provide basic data for advertising strategy and policy development. In this study, based on results of the survey, the reliability of the survey was evaluated according to each nuclear site.

  12. Spanish opinion polls 1998

    International Nuclear Information System (INIS)

    Nufiez Lopez, Maria Pilar

    1999-01-01

    There is widespread conviction among the professionals working in the nuclear sector that the image of nuclear energy held by the general public is poor. In Spain we insist again and again that an overwhelming majority of people consider nuclear energy to be dangerous, contaminating and relating to war. Depending on individual experience, we even go as far as to venture percentages of acceptability. When asked to explain the reasons for this, some claim that the cause of this attitude of rejection is to do with wastes, others that it is fear of radiation, and so on. Most of these claims are 'subjective perceptions' based on our own personal contacts and xperiences. With a view to establishing a reliable analytical basis and thus be able to carry out an objective study of the problem of public perception of nuclear energy in Spain, the Forum of the Spanish Nuclear Industry commissioned a group of external consultants specializing in this type of studies to carry out a survey designed to provide information on the causes underlying the rejection of nuclear energy and its measure. This survey is one of the first performed in this country since the decision was taken to use nuclear power in the nineteen sixties. The survey, performed by way of telephone conversations, included 2,000 people aged between 15 and 60 years. Of the total number of interviewees, 25 percent lived in areas surrounding a nuclear power plant, but had no direct professional or family ties with the plant. In addition to the 2000 telephone interviews, the study included also a qualitative investigation based on open interviews and focus groups. In general, the image detected during the qualitative phase is that in spite of its being technologically advanced and professionally directed and managed, nuclear energy arouses fear and mistrust. The structure of the survey was based on overall issues: the concerns of Spanish society. Twenty-four percent of the interviewees claimed that the environment was

  13. Islam and state school: opinions of Muslim parents in Piedmont

    Directory of Open Access Journals (Sweden)

    Renzo Guolo

    2009-07-01

    Full Text Available What are the opinions of Muslim parents, as to the teaching of Islamic religion? In case it were possible, would they prefer it to be taught in state or religious schools? And in the first case, by whom? What do families think about problems like the observance of dietary laws in school canteens, the class of physical education for girls in mixed classes, the wearing of veil? The article summarizes the data of a survey on these topics (between 2006 and 2007 carried out in Piedmont, in particular in Turin, on a sample of about 1000 people representing the different ethnonational islamic communities living in the region. The methodology employed is both quantitative (the whole sample was given a structured questionnaire and qualitative. The latter concerns detailed interviews with the leaders of Islamic associations in the region. The result is definitely in favour of the teaching of Islamic religion in state schools, together with the request to observe dietary laws, both cultural and religious, and the acceptance, on principle, of the mixed class of physical education. There are of course different opinions which, however, show a growing trend in favour of free choice as to the obligation of veil: a picture widely determined by the ethnonational origin of the interviewed, confirming the pluralism of Italian Islam. The result points out that most Muslims in Piedmont have an inclusive approach and that religion does not mean cultural separation. The main trend, apart from the opinions and projects of a few associative leaderships, is one of an Islam that wishes to become a recognized member of Italian religious and cultural scene.

  14. Seeking a second medical opinion: composition, reasons and perceived outcomes in Israel.

    Science.gov (United States)

    Shmueli, Liora; Davidovitch, Nadav; Pliskin, Joseph S; Balicer, Ran D; Hekselman, Igal; Greenfield, Geva

    2017-12-08

    Seeking a second-opinion (SO) is a common clinical practice that can optimize treatment and reduce unnecessary procedures and risks. We aim to characterize the composition of the population of SO seekers, their reasons for seeking a SO and choosing a specific physician, and their perceived outcomes following the SO. A cross-sectional national telephone survey, using a representative sample of the general Israeli population (n = 848, response rate = 62%). SO utilization was defined as seeking an additional clinical opinion from a specialist within the same specialty, for the same medical concern. We describe the characteristics of respondents who obtained SOs, their reasons for doing so and their perceived outcomes: (1) Satisfaction with the SO; (2) Experiencing health improvement after receiving a SO; (3) A difference in the diagnosis or treatment suggested in the first opinions and the second opinions; (4) Preference of the SO over the first one. Most of the respondents who sought a SO (n = 344) were above 60 years old, secular, living with a partner, perceived their income to be above average and their health status to be not so good. For the patients who utilized SOs, orthopedic surgeons were sought out more than any other medical professional.Reasons for seeking a SO included doubts about diagnosis or treatment (38%), search for a sub-specialty expert (19%) and dissatisfaction with communication (19%). SO seekers most frequently chose a specific specialist based on a recommendation from a friend or a relative (33%). About half of the SO seekers also searched for information on the internet. Most of the respondents who sought a SO mentioned that they were satisfied with it (84%), felt health improvement (77%), mentioned that there was a difference between the diagnosis or treatment between the first opinion and the SO (56%) and preferred the SO over the first one (91%). Clinical uncertainty or dissatisfaction with patient-physician communication

  15. Planning "and" Sprinting: Use of a Hybrid Project Management Methodology within a CIS Capstone Course

    Science.gov (United States)

    Baird, Aaron; Riggins, Frederick J.

    2012-01-01

    An increasing number of information systems projects in industry are managed using hybrid project management methodologies, but this shift in project management methods is not fully represented in our CIS curriculums. CIS capstone courses often include an applied project that is managed with traditional project management methods (plan first,…

  16. Exposure of maternal mice to cis-bifenthrin enantioselectively disrupts the transcription of genes related to testosterone synthesis in male offspring.

    Science.gov (United States)

    Jin, Yuanxiang; Wang, Jiangcong; Sun, Xueqing; Ye, Yang; Xu, Minjie; Wang, Jianai; Chen, Shaoping; Fu, Zhengwei

    2013-12-01

    The commercial bifenthrin (BF) contains two cis isomers. In the present study, a dose of 15mg/kg of 1R-cis-BF or 1S-cis-BF was orally administered for 3 weeks to female mice before or during pregnancy. Then, the expression of steroidogenesis related genes which were considered as effective biomarkers of endocrine disruption were analyzed in the male offspring. Maternal exposure to 1S-cis-BF during pregnancy significantly reduced the mRNA levels of peripheral benzodiazepine receptor (PBR) and steroidogenic acute regulatory protein (StAR) in the testes of 3- or 6-week old male offspring. In addition, a significant decrease of cytochrome P450 17α-hydroxysteroid dehydrogenase (P450-17α) was also observed in the testes of 6-week old male offspring when dams were treated with 1S-cis-BF during pregnancy but not before pregnancy. Moreover, the scavenger receptor class B type 1 (SRB1) and cytochrome P450 cholesterol side-chain cleavage enzyme (P450scc) decreased significantly in the testes of 6-week old male offspring when dams were treated with 1S-cis-BF during and before pregnancy. Thus, oral administration of the maternal mice to cis-BF for 3 weeks, particularly during pregnancy, resulted in endocrine disruption in the male offspring, with the 1S-cis-BF causing more significant alterations than the 1R-cis-BF form. Copyright © 2013 Elsevier Inc. All rights reserved.

  17. Public opinion on water reuse options

    International Nuclear Information System (INIS)

    Bruvold, W.H.

    1988-01-01

    Public policy on waste water reuse options must be informed by public opinion because it is the public who must pay the cost of developing the option and who will be served by the option in the future. For public policy on reuse, guidance for innovative reuse is not as simple as first believed. It seems that public opinion regarding actual community reuse options is affected by the linkage of several factors, including water conservation, health protection, treatment and distribution costs, and environmental enhancement. Probability sampling was used in 7 studies to select respondents who were queried regarding their opinions on various reclaimed water uses such as ranging from cooling tower water to full domestic use. These 7 are briefly reviewed

  18. Conformity, Anticonformity and Polarization of Opinions: Insights from a Mathematical Model of Opinion Dynamics

    Directory of Open Access Journals (Sweden)

    Tyll Krueger

    2017-07-01

    Full Text Available Understanding and quantifying polarization in social systems is important because of many reasons. It could for instance help to avoid segregation and conflicts in the society or to control polarized debates and predict their outcomes. In this paper, we present a version of the q-voter model of opinion dynamics with two types of responses to social influence: conformity (like in the original q-voter model and anticonformity. We put the model on a social network with the double-clique topology in order to check how the interplay between those responses impacts the opinion dynamics in a population divided into two antagonistic segments. The model is analyzed analytically, numerically and by means of Monte Carlo simulations. Our results show that the system undergoes two bifurcations as the number of cross-links between cliques changes. Below the first critical point, consensus in the entire system is possible. Thus, two antagonistic cliques may share the same opinion only if they are loosely connected. Above that point, the system ends up in a polarized state.

  19. Attitude and opinion towards essential medicine formulary.

    Science.gov (United States)

    Sharma, Sangeeta; Kh, Reeta; Chaudhury, R Roy

    2010-06-01

    The Delhi State Drug Policy was adopted in 1994 following which the first Essential Medicines List (EML) was developed in 1996. The Delhi State Essential Medicines Formulary was brought out in 1997. A need was felt to revise the formulary to match with the EML as the EML is renewed every 2 years. A survey was undertaken to elicit the opinions of the doctors practicing in the state on the usefulness of the formulary before revising and printing the updated version. The survey covered dispensaries, 10-20 bedded hospitals, 100-bedded hospitals and two tertiary care hospitals. Discussions were focused on questionnaires on attitudes toward adopting Essential Medicines Formulary using a 10-point scale. Of the 200 doctors approached, only 90 doctors completed the questionnaire. Sixty-nine respondents (76.6%) had received the copy of the formulary. Most practitioners welcomed the formulary and were satisfied with the coverage and selection of the medicines. Most respondents (76.9%) agreed that a well-developed formulary would improve the quality of the public health care system, although they had reservations about the authority, relevance and effect on professional autonomy. About 74% of the respondents used the formulary in clinical practice as a source of medicine information, which makes its regular revision necessary.

  20. Enhanced cis-platinum ototoxicity in children with brain tumours who have received simultaneous or prior cranial irradiation

    International Nuclear Information System (INIS)

    Walker, D.A.; Pillow, J.; Waters, K.D.; Keir, E.

    1989-01-01

    We report on four children who received cis-platinum simultaneously with, or in one case 10 months after, cranial irradiation and experienced exaggerated ototoxicity affecting all audible frequencies. The hearing loss was severe, affecting the critical areas for speech perception, and necessitated the provision of bilateral hearing aids. The audiograms of these patients are shown and compared to those of four children who had received cis-platinum as part of their treatment for neuroblastoma but without cranial irradiation. The precipitation of the exaggerated hearing loss with the administration of cis-platinum in one patient 10 months after finishing cranial irradiation suggests that care should be taken in the timing of cis-platinum administration in relation to concurrent or previous cranial irradiation