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Sample records for cirripedia thoracica implications

  1. Comparison of nutritional status of field and laboratory reared Balanus amphitrite Darwin (Cirripedia: Thoracica) larvae and implication of starvation

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, D.V.; Anil, A.C.

    Comparison of nutritional status of field and laboratory reared Balanus amphitrite Darwin (Cirripedia: Thoracica) larvae and implication of starvation Dattesh V. Desai, A.C. Anil * Marine Corrosion and Materials Research Division, National Institute... (Thorson, 1950; Crisp, 1976; Olson and Olson, 1989; Anil et al., 1995). Starvation will lead to nutritional stress, which can kill the larvae directly or may increase or decrease the duration of larval developmental stages (Knowlton, 1974; Sandifer...

  2. Cypris morphology in the barnacles Ibla and Paralepas (Crustacea: Cirripedia Thoracica) implications for cirripede evolution

    DEFF Research Database (Denmark)

    Høeg, Jens T; Achituv, Yair; Chan, Benny K K;

    2009-01-01

    are of the pore-field type and the terminal pore is situated anteriorly in the first pair, just as in the Rhizocephala and the Thoracica. In Ibla the armament of antennular sensilla resembles that found in the Thoracica but differs from the Rhizocephala. The absence of setules on the A and B setae sited...

  3. Molecular phylogeny and character evolution of the chthamaloid barnacles (Cirripedia:Thoracica)

    DEFF Research Database (Denmark)

    Pérez-Losada, Marcos; Høeg, Jens Thorvald; Crandall, Keith A.;

    2012-01-01

    of the Chthamaloidea has been debated since Darwin's seminal monographs. Theories of morphological and ontogenetic evolution suggest that the group could have evolved multiple times from pedunculated relatives and that shell plate number diminished gradually (8¿6¿4) from an ancestral state with eight wall plates......The Chthamaloidea (Balanomorpha) present the most plesiomorphic characters in shell plates and cirri, mouthparts, and oral cone within the acorn barnacles (Thoracica: Sessilia). Due to their importance in understanding both the origin and diversification of the Balanomorpha, the evolution...... surrounded by whorls of small imbricating plates; but this hypothesis has never been subjected to a rigorous phylogenetic test. Here we used multilocus sequence data and extensive taxon sampling to build a comprehensive phylogeny of the Chthamaloidea as a basis for understanding their morphological evolution...

  4. Phylogeny and evolution of life history strategies of the Parasitic Barnacles (Crustacea, Cirripedia, Rhizocephala)

    DEFF Research Database (Denmark)

    Glenner, Henrik; Hebsgaard, Martin Bay

    2006-01-01

    The barnacles (Crustacea, Cirripedia) consist of three well-defined orders: the conventional filter-feeding barnacles (Thoracica), the burrowing barnacles (Acrothoracica), and the parasitic barnacles (Rhizocephala). Thoracica and Acrothoracica feed by catching food particles from the surrounding...... to resolve the phylogenetic relationship of the order Rhizocephala and elucidate the evolution of the different life history strategies found within the Rhizocephala, we have performed the first comprehensive phylogenetic analysis of the group. Our results indicate that Rhizocephala is monophyletic...

  5. Reproduction and larval development in three scalpellid barnacles, Scalpellum scalpellum (Linnaeus 1767), Ornatoscalpellum stroemii (M. Sars 1859) and Arcoscalpellum michelottianum (Seguenza 1876), Crustacea: Cirripedia: Thoracica): implications for reproduction

    DEFF Research Database (Denmark)

    Buhl-Mortensen, Lene; Høeg, Jens Thorvald

    2006-01-01

    than the other two species. We hypothesize that the observed differences in reproductive system and mode of development in the three species represent adaptations to their different habitats. S. scalpellum are mainly transported by currents in the coastal sublittoral zone. O. stroemii is presumably......We studied reproduction and larval development in three species of pedunculated barnacles with different depth distribution, that is, Scalpellum scalpellum (30-200 m), Ornatoscalpellum stroemii (100-1,600 m) and Arcoscalpellum michelottianum (64-5,190 m). Morphology, position and number of males...... in the female/hermaphrodite, type of larval development and the number and size of eggs were recorded. All three species have a pair of pocket-like receptacles, each of which can host only a single male in O. stroemii, up to five males in S. scalpellum and up to 12 males in A. michelottianum. Eggs and larvae...

  6. Studies on some ecological aspects of Balanus amphitrite (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, D.V.

    The year round breeding capability of Balanus amphitrite indicates a potential for continuous recruitment. The recruitment pattern however indicated a lull during monsoon. The study site experiences increased land run off lowering the salinity...

  7. Exploration and metamorphosis in Balanus amphitrite Darwin (Cirripedia ; Thoracica) cyprids: significance of sugars and adult extract

    Digital Repository Service at National Institute of Oceanography (India)

    Khandeparker, L.; Anil, A.C.; Raghukumar, S.

    footprints when exposed to multiwells coated with AE. A comparison of observations between single cyprid and multiple cyprid assays showed a similar trend, thus indicating that larva-larva interaction may not play an important role, when such pretreated...

  8. Physiological responses to hypoxia and anoxia in Balanus amphitrite (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, D.V.; Prakash, S.

    (hypoxia) and no oxygen (anoxia) on B. amphitrite adults and nauplii was assessed. Their response was evaluated by estimating the levels of the antioxidant enzymes catalase and superoxide dismutase. The impact of desiccation on antioxidant enzymes in adult...

  9. Studies on some cues regulating metamorphosis of the larvae of Balanus amphitrite (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Khandeparker, L.

    suitable place to settle. The cyprid footprints have also been reported to induce settlement of other cyprids, even in the absence of conspecific adults (Walker and Yule 1984; Yule and Walker 1985; Clare et al. 1994). Chemical cues such as bacterial... of bacterial exopolysaccharides from both marine and freshwater environments (Sutherland 1980). The interactions between bacterial exopolymers and cypris temporary adhesive are most likely to be effected via polar groups. The strength of these interactions...

  10. Significance of biofilm proteins in modulating cyprid metamorphosis of Balanus amphitrite (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Khandeparker, L.; KrishnaKumar, S.

    address:klidita@nio.org (Lidita Khandeparker) 2 Problem Biofouling is a prominent feature on artificial structures like ship hulls, underwater pipelines, bridges, offshore platforms etc. that results in their modification leading...

  11. Reproduction in Balanus amphitrite Darwin (Cirripedia: Thoracica); influence of temperature and food concentration

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, D.V.; Anil, A.C.; Venkat, K.

    the numbers of larvae released vs. the number of days (experimental schedule) for which the barnacles were raised indicated that the number of larvae released increased with the age of the barnacles. This increase was significant in case the of barnacles...

  12. Influence of temperature on the starvation threshold of nauplii of barnacle Balanus amphitrite (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, D.V.; Anil, A.C

    An evaluation of starvation threshold of the newly hatched Balanus amphitrite nauplii (instar, II) has been made at three different temperatures (5, 15 and 25°C). Earlier studies on starvation in crustacean larvae demonstrated Point of No Return...

  13. Growth and molting in epizoic pedunculate barnacles genus Octolasmis (Crustacea: Thecostraca: Cirripedia: Thoracica)

    DEFF Research Database (Denmark)

    Blomsterberg, Mikkel; Glenner, Henrik; Høeg, Jens T

    2004-01-01

    layers is entirely restricted to the growth zones. Just prior to ecdysis, the new cuticle lies in a highly folded fashion beneath the old cuticle that is about to be shed. At ecdysis, the old cuticle breaks along the margins of the growth zones and the resulting scars remain as a system of "ecdysial...... that size increase is due to the formation of new cuticle by molting in the growth zones, while expansion of the shell plates by mineralization follows only after production of the new cuticle. Thus, although specialized, growth in Octolasmis still complies with the general crustacean model, complicated...

  14. Notes on the ultrastructure of the setae on the fourth antennulary segment of the Balanus amphitrite cyprid (Crustacea : Cirripedia : Thoracica)

    DEFF Research Database (Denmark)

    Lagersson, Niklas; Garm, Anders Lydik; Høeg, Jens Thorvald

    2003-01-01

    while one seta (sE) is presumed to be a unimodal mechanoreceptor. We suggest that setae A and B are stimulated by the water flow, seta D is olfactory, seta E detects the topography of the substratum by touch, and the subterminal setae are touch chemoreceptors. No function is suggested for seta C....

  15. Influence of bacterial exopolymers, conspecific adult extract and salinity on the cyprid metamorphosis of Balanus amphitrite (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Anil, A.C.; Khandeparker, R.

    The influence of bacterial exopolymers and conspecific adult extract of Balanus amphitrite on metamorphosis of cyprid larvae at different salinities has been evaluated through laboratory assay. The bacterial exopolymers (epm) extracted from...

  16. The impact of food type, temperature and starvation on larval development of Balanus amphitrite Darwin (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, D.V.; Anil, A.C.

    The impact of diatom food species (Chaetoceros calcitrans and Skeletonema costatum), temperature and starvation on the larval development of Balanus amphitrite was evaluated. Starvation threshold levels for different ages of larvae (0- to 5-day...

  17. Larval development and metamorphosis in Balanus amphitrite Darwin (Cirripedia; Thoracica): Significance of food concentration, temperature and nucleic acids

    Digital Repository Service at National Institute of Oceanography (India)

    Anil, A.C.; Desai, D.V.; Khandeparker, L.

    barnacles to compete for space and seriously reduce their likelihood of successfully recruiting to the adult population. In Ž. Ž. the light of these observations, Jarrett and Pechenik 1997 and Pechenik et al. 1998 opined that larval experience influences... during the course of this work. We thank Dr. S.S. Sawant and Mr. K. Venkat Ž. and other colleagues of MCMRD for their help. The authors D.D and L.K greatly acknowledge CSIR, India for the award of Senior Research Fellowships. This work was Ž.[] supported...

  18. A coral-eating barnacle, revisited (Cirripedia, Pyrgomatidae)

    NARCIS (Netherlands)

    Ross, Arnold; Newman, William A.

    1995-01-01

    The coral-eating barnacle Hoekia monticulariae (Gray, 1831), the only internal parasite among the Thoracica described to this day, is characterized by an irregularly-shaped shell nestled cryptically between the polyps of the hermatypic coral Hydnophora Fischer, 1807, which occurs throughout most of

  19. Southern hemisphere deep-water stylasterid corals including a new species, Errina labrosa sp. n. (Cnidaria, Hydrozoa, Stylasteridae, with notes on some symbiotic scalpellids (Cirripedia, Thoracica, Scalpellidae

    Directory of Open Access Journals (Sweden)

    Daniela Pica

    2015-01-01

    Full Text Available A number of stylasterid corals are known to act as host species and create refuges for a variety of mobile and sessile organisms, which enhances their habitat complexity. These include annelids, anthozoans, cirripeds, copepods, cyanobacteria, echinoderms, gastropods, hydroids and sponges. Here we report the first evidence of a diverse association between stylasterids and scalpellid pedunculate barnacles and describe a new stylasterid species, Errina labrosa, from the Tristan da Cunha Archipelago. Overall, five stylasterid species are found to host eight scalpellid barnacles from several biogeographic regions in the southern hemisphere (Southern Ocean, temperate South America and the southern Indo-Pacific realms. There is an apparent lack of specificity in this kind of association and different grades of reaction to the symbiosis have been observed in the coral. These records suggest that the association between pedunculate barnacles and hard stylasterid corals has a wide distribution among different biogeographic realms and that it is relatively rare and confined largely to deep water.

  20. Interactive effect of elevated pCO2 and temperature on the larval development of an inter-tidal organism, Balanus amphitrite Darwin (Cirripedia: Thoracica)

    Digital Repository Service at National Institute of Oceanography (India)

    Baragi, L.V.; Anil, A.C.

    mechanism that catalyses the build-up of CO2 around the RuBisCO by active transport of HCO3- into the cell under CO2 limited condition at the expense of high metabolic energy (Raven et al., 2008). The present study found, irrespective of temperature...., 2012; Wu et al., 2010); negative (Gao et al., 2012; Torstensson et al., 2012) or neutral (Gao et al., 2012; Yang and Gao, 2012). The difference in responses could be attributed to varying Carbon Concentrating Mechanism (CCM) which is an efficient...

  1. Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica

    Science.gov (United States)

    Ariki, Nathanial K.; Muñoz, Lisa E.; Armitage, Elizabeth L.; Goodstein, Francesca R.; George, Kathryn G.; Smith, Vanessa L.; Vetter, Irina; Herzig, Volker; King, Glenn F.; Loening, Nikolaus M.

    2016-01-01

    We present the solution-state NMR structures and preliminary functional characterizations of three venom peptides identified from the spitting spider Scytodes thoracica. Despite little sequence identity to other venom peptides, structural characterization reveals that these peptides contain an inhibitor cystine knot motif common to many venom peptides. These are the first structures for any peptide or protein from spiders of the Scytodidae family. Many venom peptides target neuronal ion channels or receptors. However, we have not been able to determine the target of these Scytodes peptides so we can only state with certainty the channels and receptors that they do not target. PMID:27227898

  2. Characterization of Three Venom Peptides from the Spitting Spider Scytodes thoracica.

    Directory of Open Access Journals (Sweden)

    Nathanial K Ariki

    Full Text Available We present the solution-state NMR structures and preliminary functional characterizations of three venom peptides identified from the spitting spider Scytodes thoracica. Despite little sequence identity to other venom peptides, structural characterization reveals that these peptides contain an inhibitor cystine knot motif common to many venom peptides. These are the first structures for any peptide or protein from spiders of the Scytodidae family. Many venom peptides target neuronal ion channels or receptors. However, we have not been able to determine the target of these Scytodes peptides so we can only state with certainty the channels and receptors that they do not target.

  3. Sympatric three-species infection by Sacculina parasites (Cirripedia: Rhizocephala: Sacculinidae) of an intertidal grapsoid crab

    DEFF Research Database (Denmark)

    Tsuchida, Kohei; Lützen, Jørgen; Nishida, Mutsumi

    2006-01-01

    Parasitization by sacculinids (Cirripedia: Rhizocephala: Sacculinidae) induces severe modifications in morphology, behavior, and reproduction of their host crabs. To understand the mechanisms involved, it is important to have comprehensive information on their association. However, such information...... of Sacculina, S. confragosa, S. imberbis, and S. yatsui, were found to parasitize a single host crab, Pachygrapsus crassipes, sympatrically in a restricted area. This is the first finding for three-on-one association in a single locality....

  4. Over de eerste vondsten van twee Pennella-soorten (Crustacea: Copepoda) en van Conchoderma virgatum (Spengler) (Crustacea: Cirripedia) in Nederland

    NARCIS (Netherlands)

    Huwae, P.H.M.

    1986-01-01

    On 30 November 1941 a sunfish Mola mola (L.) was found on the beach near Schoorl (Province of Noord-Holland). The fish was parasitized by a specimen of Pennella filosa (L.) (Crustacea, Copepoda) on which a specimen of Conchoderma virgatum (Crustacea: Cirripedia) had attached itself. This is the firs

  5. Larval development of the pedunculate barnacles Octolasmis angulata Aurivillius 1894 and Octolasmis cor Aurivillius 1892 (Cirripedia: Thoracica: Poecilasmatidae) from the gills of the mud crab, Scylla tranquebarica Fabricius, 1798.

    Science.gov (United States)

    Yap, F C; Wong, W L; Maule, A G; Brennan, G P; Lim, L H S

    2015-05-01

    Detailed studies of larval development of Octolasmis angulata and Octolasmis cor are pivotal in understanding the larval morphological evolution as well as enhancing the functional ecology. Six planktotrophic naupliar stages and one non-feeding cyprid stage are documented in details for the first time for the two species of Octolasmis. Morphologically, the larvae of O. angulata and O. cor are similar in body size, setation patterns on the naupliar appendages, labrum, dorsal setae-pores, frontal horns, cyprid carapace, fronto-lateral gland pores, and lattice organs. Numbers of peculiarities were observed on the gnathobases of the antennae and mandible throughout the naupliar life-cycle. The setation pattern on the naupliar appendages are classified based on the segmentation on the naupliar appendages. The nauplius VI of both species undergoes a conspicuous change before metamorphosis into cyprid stage. The cyprid structures begin to form and modify beneath the naupliar body towards the end of stage VI. This study emphasises the importance of the pedunculate barnacle larval developmental studies not only to comprehend the larval morphological evolution but also to fill in the gaps in understanding the modification of the naupliar structures to adapt into the cyprid life-style. PMID:25770075

  6. Influence of food concentration, temperature and salinity on the larval development of Balanus amphitrite

    Digital Repository Service at National Institute of Oceanography (India)

    Anil, A.C.; Kurian, J.

    Influence of food concentration (0.5, 1 and 2 x 10 sup(5) cell ml sup(-1) of Skeletonema costatum), temperature (20 and 30 degrees C) and salinity (15, 25 and 35 ppt) on the larval development of Balanus amphitrite (Cirripedia: Thoracica...

  7. Why Williamson's (2014) theory of Hybridogenesis fails to explain the evolution of the Rhizocephala

    DEFF Research Database (Denmark)

    Glenner, Henrik; Lytzen, Jørgen Gjerom

    2015-01-01

    Alle biologiske, ultrastrukturelle og molekylære data understøtter konlusionen at subordernerne Cirripedia, Rhizocephala og Thoracica er nært beslægtede. Williamsons spekulationer, nemlig at den såkaldte hybridogenesis kan forklare hvo ledes Rhizocepahlerne har udviklet sig, hviler på et selektiv...

  8. Intuitionistic implication without disjunction

    NARCIS (Netherlands)

    Renardel de Lavalette, Gerard R.; Hendriks, Alex; Jongh, Dick H.J. de

    2012-01-01

    We investigate fragments of intuitionistic propositional logic containing implication but not disjunction. These fragments are finite, but their size grows superexponentially with the number of generators. Exact models are used to characterize the fragments.

  9. Implications of antisocial parents.

    Science.gov (United States)

    Torry, Zachary D; Billick, Stephen B

    2011-12-01

    Antisocial behavior is a socially maladaptive and harmful trait to possess. This can be especially injurious for a child who is raised by a parent with this personality structure. The pathology of antisocial behavior implies traits such as deceitfulness, irresponsibility, unreliability, and an incapability to feel guilt, remorse, or even love. This is damaging to a child's emotional, cognitive, and social development. Parents with this personality makeup can leave a child traumatized, empty, and incapable of forming meaningful personal relationships. Both genetic and environmental factors influence the development of antisocial behavior. Moreover, the child with a genetic predisposition to antisocial behavior who is raised with a parental style that triggers the genetic liability is at high risk for developing the same personality structure. Antisocial individuals are impulsive, irritable, and often have no concerns over their purported responsibilities. As a parent, this can lead to erratic discipline, neglectful parenting, and can undermine effective care giving. This paper will focus on the implications of parents with antisocial behavior and the impact that this behavior has on attachment as well as on the development of antisocial traits in children.

  10. Neutrino Experiments and Their Implications

    OpenAIRE

    Balantekin, A. B.

    2004-01-01

    Recent developments in solar, reactor, and accelerator neutrino physics are reviewed. Implications for neutrino physics, solar physics, nuclear two-body physics, and r-process nucleosynthesis are briefly discussed.

  11. Biological features on epibiosis of Amphibalanus improvisus (Cirripedia on Macrobrachium acanthurus (Decapoda

    Directory of Open Access Journals (Sweden)

    Cristiane Maria Rocha Farrapeira

    2010-06-01

    Full Text Available This study aimed to describe the epibiosis of barnacles Amphibalanus improvisus on eight adult Macrobrachium acanthurus males from the Mundaú Lagoon, state of Alagoas, Brazil. The number of epibiont barnacles varied from 247 to 1,544 specimens per prawn; these were distributed predominantly on the cephalothorax and pereiopods, but also on the abdomen and other appendices. Although some were already reproducing, most barnacles had been recruited recently or were still sexually immature; this suggests recent host arrival in that estuarine environment. Despite the fact that other barnacles occur in this region, A. improvisus is the only species reported as an epibiont on Macrobrachium acanthurus; this was also the first record of epibiosis on this host. The occurrence of innumerable specimens in the pereiopods' articulations and the almost complete covering of the carapace of some prawns (which also increased their weight suggest that A. improvisus is adapted to fixate this kind of biogenic substrate and that the relationship between the two species biologically damages the basibiont.O objetivo deste trabalho foi relatar a epibiose de cirrípedes Amphibalanus improvisus em oito camarões machos adultos da espécie Macrobrachium acanthurus provenientes da Laguna Mundaú, Alagoas, Brasil. O número de cirrípedes epibiontes variou desde 247 até 1.544 espécimes por camarão, distribuídos predominantemente no cefalotórax e pereiópodos, mas presentes também no abdome e demais apêndices. A grande maioria dos cirrípedes era recém-recrutada ou ainda estava sexualmente imatura, embora de alguns estivessem já em reprodução, sugerindo a chegada recente de seu hospedeiro no ambiente estuarino. Apesar de ocorrem outros cirrípedes na região, A. improvisus foi à única espécie relatada como epibionte em Macrobrachium acanthurus e isto se constituiu o primeiro registro de epibiose de Amphibalanus improvisus A ocorrência de inúmeros espécimes nas articulações dos pereiópodos e o recobrimento quase total da carapaça de alguns camarões (incrementando peso aos mesmos indicam que a espécie epibionte está adaptada à fixação neste substrato biogênico e que a relação entre estas duas espécies traz prejuízos biológicos ao basibionte.

  12. A Study of the Morphology and Biology of Thompsonia littoralis (Crustacea: Cirripedia: Rhizocephala)

    DEFF Research Database (Denmark)

    Lützen, Jørgen; Jespersen, Åse

    1992-01-01

    of the thoracic appendages. As many externae drop off, their number is continuously reduced; the survivors reach sexual maturity and ovulate after 2.5 months and complete embryonic development after 2 more months. At the next moult a new and more numerous generation of externae appears, and this is repeated until...

  13. Biodiversity and Biogeography of Chthamalid Barnacles from the North-Eastern Pacific (Crustacea Cirripedia).

    Science.gov (United States)

    Chan, Benny K K; Chen, H-N; Dando, P R; Southward, A J; Southward, E C

    2016-01-01

    The biogeography and ecology of the species of Chthamalus present on the west coast of America are described, using data from 51 localities from Alaska to Panama, together with their zonation on the shore with respect to that of other barnacles. The species present were C. dalli, Pilsbry 1916, C. fissus, Darwin, 1854, C. anisopoma Pilsbry 1916 and four species in the C. panamensis complex. The latter are C. panamensis Pilsbry, 1916, C. hedgecocki, Pitombo & Burton, 2007, C. alani nom. nov. (formerly C. southwardorum Pitombo & Burton, 2007) and C. newmani sp. nov.). These four species were initially separated by enzyme electrophoresis. They could only be partially separated by DNA bar coding but may be separated using morphological characters.

  14. The unusual floatation collar around nauplii of certain parasitic barnacles (Crustacea: Cirripedia: Rhizocephala)

    DEFF Research Database (Denmark)

    Høeg, Jens Thorvald; Møller, Ole Sten; Rybakov, Alexey V.

    2004-01-01

    microscopy shows that the collar of the succeeding nauplius instar is formed in an unexpanded state beneath the old cuticle and it must therefore be inflated at or immediately after ecdysis. At ecdysis the collar of the old instar breaks along the attachment ridge, leaving the empty collar and the exuvium...

  15. Phylogenetic position and evolutionary history of the turtle and whale barnacles (Cirripedia: Balanomorpha: Coronuloidea).

    Science.gov (United States)

    Hayashi, Ryota; Chan, Benny K K; Simon-Blecher, Noa; Watanabe, Hiromi; Guy-Haim, Tamar; Yonezawa, Takahiro; Levy, Yaniv; Shuto, Takuho; Achituv, Yair

    2013-04-01

    Barnacles of the superfamily Coronuloidea are obligate epibionts of various marine mammals, marine reptiles and large crustaceans. We used five molecular markers: 12S rDNA, 16S rDNA, 18S rDNA, 28S rDNA and Histone 3 to infer phylogenetic relationships among sixteen coronuloids, representing most of the recent genera of barnacles of this superfamily. Our analyses confirm the monophyly of Coronuloidea and that this superfamily and Tetraclitoidea are sister groups. The six-plated Austrobalanus clusters with these two superfamilies. Based on BEAST and ML trees, Austrobalanus is basal and sister to the Coronuloidea, but the NJ tree places Austrobalanus within the Tetraclitoidae, and in the MP tree it is sister to both Coronuloidea and Tetraclitoidae. Hence the position of Austrobalanus remains unresolved. Within the Coronuloidea we identified four clades. Chelonibia occupies a basal position within the Coronuloidea which is in agreement with previous studies. The grouping of the other clades does not conform to previous studies. Divergence time analyses show that some of the time estimates are congruent with the fossil record while some others are older, suggesting the possibility of gaps in the fossil record. PMID:23306306

  16. Biodiversity and Biogeography of Chthamalid Barnacles from the North-Eastern Pacific (Crustacea Cirripedia.

    Directory of Open Access Journals (Sweden)

    Benny K K Chan

    Full Text Available The biogeography and ecology of the species of Chthamalus present on the west coast of America are described, using data from 51 localities from Alaska to Panama, together with their zonation on the shore with respect to that of other barnacles. The species present were C. dalli, Pilsbry 1916, C. fissus, Darwin, 1854, C. anisopoma Pilsbry 1916 and four species in the C. panamensis complex. The latter are C. panamensis Pilsbry, 1916, C. hedgecocki, Pitombo & Burton, 2007, C. alani nom. nov. (formerly C. southwardorum Pitombo & Burton, 2007 and C. newmani sp. nov.. These four species were initially separated by enzyme electrophoresis. They could only be partially separated by DNA bar coding but may be separated using morphological characters.

  17. THE ACTUAL IMPLICATIONS OF INFLATION

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    Murăriţa Ilie

    2011-12-01

    Full Text Available The authors have started from the idea that inflationary phenomenon is a companion, the cause and the effect of the globalization of poverty in the broader context of world economy globalization. Therefore, starting from a common definition of inflation, the first objective was to identify causal relationships that singularize contemporary inflationary process. After that, attention was focused on the implications of inflation in the current stage, bearing in mind that monetary financial theory and practice are operating with perfectly anticipated inflation or imperfectly anticipated inflation. Inflation has great implications on the long-term contracts and wage contracts.

  18. Mind, Matter and the Implicate Order The Implicate Order Revisited

    CERN Document Server

    Pylkkänen, Paavo T I

    2007-01-01

    Proposes that Bohm's alternative interpretation of quantum theory resolves the paradoxes such as Schrodinger's cat, and the EPR paradox. This work uses Bohm's concepts of "implicate order", "active information" and "soma-significance" as tools to tackle several well-known problems in the philosophy of mind.

  19. Educational Implications of the Bender.

    Science.gov (United States)

    Petti, Michael

    1988-01-01

    Examples of diagnostic formulations of the "Bender Visual-Motor Gestalt" are outlined and their instructional implications are delineated. The difficulties in paper and pencil copying of geometric designs focus primarily on: separation and overlapping of figures, repetition of design elements, pencil grip, visual perceptions, pattern reversals,…

  20. Astrosociological Implications of Astrobiology (Revisited)

    Science.gov (United States)

    Pass, Jim

    2010-01-01

    Supporters of astrobiology continue to organize the field around formalized associations and organizations under the guise of the so-called ``hard'' sciences (e.g., biology and the related physical/natural sciences). The so-called ``soft'' sciences-including sociology and the other social sciences, the behavioral sciences, and the humanities-remain largely separated from this dynamically growing field. However, as argued in this paper, space exploration involving the search for extraterrestrial life should be viewed as consisting of two interrelated parts (i.e., two sides of the same coin): astrobiology and astrosociology. Together, these two fields broadly combine the two major branches of science as they relate to the relationship between human life and alien life, as appropriate. Moreover, with a formalized system of collaboration, these two complimentary fields would also focus on the implications of their research to human beings as well as their cultures and social structures. By placing the astrosociological implications of astrobiology at a high enough priority, scientists interested in the search for alien life can augment their focus to include the social, cultural, and behavioral implications that were always associated with their work (yet previously overlooked or understated, and too often misunderstood). Recognition of the astrosociological implications expands our perception about alien life by creating a new emphasis on their ramifications to human life on Earth.

  1. Corporate Social Responsibility: Strategic Implications

    OpenAIRE

    Abagail McWilliams; Siegel, Donald S.; Patrick M. Wright

    2005-01-01

    We describe a variety of perspectives on corporate social responsibility (CSR), which we use to develop a framework for consideration of the strategic implications of CSR. Based on this framework, we propose an agenda for additional theoretical and empirical research on CSR. We then review the papers in this special issue and relate them to the proposed agenda.

  2. Policy Implications of Education Informatics

    Science.gov (United States)

    Carr, Jo Ann; O'Brien, Nancy P.

    2010-01-01

    Background/Context: This concluding article identifies the policy implications of education informatics and explores impacts of current copyright laws, legislative structures, publishing practices, and education organizations. Synthesizing the discussions in the preceding articles, this article highlights the importance of designing information…

  3. A Bayesian Model for Discovering Typological Implications

    CERN Document Server

    Daumé, Hal

    2009-01-01

    A standard form of analysis for linguistic typology is the universal implication. These implications state facts about the range of extant languages, such as ``if objects come after verbs, then adjectives come after nouns.'' Such implications are typically discovered by painstaking hand analysis over a small sample of languages. We propose a computational model for assisting at this process. Our model is able to discover both well-known implications as well as some novel implications that deserve further study. Moreover, through a careful application of hierarchical analysis, we are able to cope with the well-known sampling problem: languages are not independent.

  4. Cosmological implications of Heisenberg's principle

    CERN Document Server

    Gonzalo, Julio A

    2015-01-01

    The aim of this book is to analyze the all important implications of Heisenberg's Uncertainty Principle for a finite universe with very large mass-energy content such as ours. The earlier and main contributors to the formulation of Quantum Mechanics are briefly reviewed regarding the formulation of Heisenberg's Principle. After discussing “indeterminacy” versus ”uncertainty”, the universal constants of physics are reviewed and Planck's units are given. Next, a novel set of units, Heisenberg–Lemaitre units, are defined in terms of the large finite mass of the universe. With the help of Heisenberg's principle, the time evolution of the finite zero-point energy for the universe is investigated quantitatively. Next, taking advantage of the rigorous solutions of Einstein's cosmological equation for a flat, open and mixed universe of finite mass, the most recent and accurate data on the “age” (to) and the expansion rate (Ho) of the universe and their implications are reconsidered.

  5. Error Analysis and Its Implication

    Institute of Scientific and Technical Information of China (English)

    崔蕾

    2007-01-01

    Error analysis is the important theory and approach for exploring the mental process of language learner in SLA. Its major contribution is pointing out that intralingual errors are the main reason of the errors during language learning. Researchers' exploration and description of the errors will not only promote the bidirectional study of Error Analysis as both theory and approach, but also give the implication to second language learning.

  6. Female genital cutting: nursing implications.

    Science.gov (United States)

    Goldenstein, Rachel A

    2014-01-01

    Female genital cutting (FGC) is a practice that affects millions of girls and women worldwide. This deeply rooted practice has cultural, religious, and psychosexual meaning to its practitioners, but it also carries long-term physical and mental complications. Decried as a human rights violation, nonetheless this practice is still carried out today. Nurses are in a unique position to contact and educate women who have been cut or are at risk for mutilation. To advocate for these women, a thorough understanding of the practice of FGC, its cultural overtones, religious implications, and psychosexual effects is needed. PMID:23835896

  7. Pharmacogenomics and migraine: possible implications

    DEFF Research Database (Denmark)

    Tfelt-Hansen, P.; Brosen, K.

    2008-01-01

    Pharmacogenomics is the science about how inherited factors influence the effects of drugs. Drug response is always a result of mutually interacting genes with important modifications from environmental and constitutional factors. Based on the genetic variability of pharmacokinetic and in some...... cases pharmacodynamic variability we mention possible implications for the acute and preventive treatment of migraine. Pharmacogenomics will most likely in the future be one part of our therapeutic armamentarium and will provide a stronger scientific basis for optimizing drug therapy on the basis...

  8. Networking activism: implications for Greece

    Directory of Open Access Journals (Sweden)

    Pantelis Vatikiotis

    2011-12-01

    Full Text Available The outbreak of December 2008 against police brutality through a wave of demonstrations and street protests in Athens, which was strongly advocated by protest activities and practices across the world, addresses several issues in relation to the transformative potentials of mediated collective action. The paper critically evaluates different accounts of December events, probing then into thevery networking of that movement. From this perspective, it points out another aspect of the local-global interplay in protest culture along new mediating practices (beyond the creation of transnational publics, that of the implications of transnational networking for local social activism and identification, addressing relevant questions in the Greek context.

  9. Practical implications of 'postmodern philosophy'

    Directory of Open Access Journals (Sweden)

    Savić Mile V.

    2002-01-01

    Full Text Available The article examines the implications of the discourse about postmodernity. Postmodernity is analyzed as a complex discursive figure. Within the discourse about postmodernity three levels are distinguished: the postmodern condition, postmodernism, and reflection of the postmodern condition. Special attention is paid to globalization and the problem of the enforcement of modern projects in East-European societies, particularly Serbia. These societies are termed object-societies, while their modification of modernity is called eastmodernity. The author's answer to the complexity of the postmodern condition is a conception of the politics of subsistence.

  10. Philosophical Implications of Inflationary Cosmology

    CERN Document Server

    Knobe, J; Vilenkin, A; Knobe, Joshua; Olum, Ken D.; Vilenkin, Alexander

    2003-01-01

    Recent developments in cosmology indicate that every history having a nonzero probability is realized in infinitely many distinct regions of spacetime. Thus, it appears that the universe contains infinitely many civilizations exactly like our own, as well as infinitely many civilizations that differ from our own in any way permitted by physical laws. We explore the implications of this conclusion for ethical theory and for the doomsday argument. In the infinite universe, we find that the doomsday argument applies only to effects which change the average lifetime of all civilizations, and not those which affect our civilization alone.

  11. Ophthalmic implications of seasonal affective disorder

    International Nuclear Information System (INIS)

    A review of seasonal affective disorder (SAD) is presented with a discussion of its standard treatment of phototherapy. A number of ophthalmic implications related to SAD are proposed. These implications relate to both the condition and the phototherapy used in its treatment, especially the use of full spectrum light which contains ultraviolet and near ultraviolet radiation. 12 references

  12. MARKETING IMPLICATION IN WINE ECONOMY

    Directory of Open Access Journals (Sweden)

    Ştefan MATEI

    2014-11-01

    Full Text Available The wine, a very complex product in viticulture, has proved its tremendous importance not only to the individual but rational nutrition and increasing national income of a country cultivators (evidenced by the upward trend of the share of crop production horticulture and viticulture in the global economy agricultural. More interesting is, given the continued growth in the number of scientific publications and their quality (at least since the 1980s - where "wine" is the centerpiece of these studies - we can not but be witnessing a growing interest more to this "potion" and found that the growing popularity of wine in the science reveals the emergence of a new academic field, ie "wine economy" (or wine-economy. This study aims to make a foray into "wine economy" and to outline some of the implications of marketing in this area.

  13. On the Product and Factorization of Lattice Implication Algebras

    Institute of Scientific and Technical Information of China (English)

    秦克云; 宋振明; 等

    1993-01-01

    In this paper,the concepts of product and factorization of lattice implication algebra are proposed,the relation between lattice implication product algebra and its factors and some properties of lattice implication product algebras are discussed.

  14. Mining TCGA data using Boolean implications.

    Science.gov (United States)

    Sinha, Subarna; Tsang, Emily K; Zeng, Haoyang; Meister, Michela; Dill, David L

    2014-01-01

    Boolean implications (if-then rules) provide a conceptually simple, uniform and highly scalable way to find associations between pairs of random variables. In this paper, we propose to use Boolean implications to find relationships between variables of different data types (mutation, copy number alteration, DNA methylation and gene expression) from the glioblastoma (GBM) and ovarian serous cystadenoma (OV) data sets from The Cancer Genome Atlas (TCGA). We find hundreds of thousands of Boolean implications from these data sets. A direct comparison of the relationships found by Boolean implications and those found by commonly used methods for mining associations show that existing methods would miss relationships found by Boolean implications. Furthermore, many relationships exposed by Boolean implications reflect important aspects of cancer biology. Examples of our findings include cis relationships between copy number alteration, DNA methylation and expression of genes, a new hierarchy of mutations and recurrent copy number alterations, loss-of-heterozygosity of well-known tumor suppressors, and the hypermethylation phenotype associated with IDH1 mutations in GBM. The Boolean implication results used in the paper can be accessed at http://crookneck.stanford.edu/microarray/TCGANetworks/.

  15. Mining TCGA data using Boolean implications.

    Directory of Open Access Journals (Sweden)

    Subarna Sinha

    Full Text Available Boolean implications (if-then rules provide a conceptually simple, uniform and highly scalable way to find associations between pairs of random variables. In this paper, we propose to use Boolean implications to find relationships between variables of different data types (mutation, copy number alteration, DNA methylation and gene expression from the glioblastoma (GBM and ovarian serous cystadenoma (OV data sets from The Cancer Genome Atlas (TCGA. We find hundreds of thousands of Boolean implications from these data sets. A direct comparison of the relationships found by Boolean implications and those found by commonly used methods for mining associations show that existing methods would miss relationships found by Boolean implications. Furthermore, many relationships exposed by Boolean implications reflect important aspects of cancer biology. Examples of our findings include cis relationships between copy number alteration, DNA methylation and expression of genes, a new hierarchy of mutations and recurrent copy number alterations, loss-of-heterozygosity of well-known tumor suppressors, and the hypermethylation phenotype associated with IDH1 mutations in GBM. The Boolean implication results used in the paper can be accessed at http://crookneck.stanford.edu/microarray/TCGANetworks/.

  16. Climatic implications of ice microphysics

    Energy Technology Data Exchange (ETDEWEB)

    Liou, K.N. [Univ. of Utah, Salt Lake City, UT (United States)

    1995-09-01

    Based on aircraft measurements of mid-latitude cirrus clouds, ice crystal size distribution and ice water content (IWC) are shown to be dependent on temperature. This dependence is also evident from the theoretical consideration of ice crystal growth. Using simple models of the diffusion and accretion growth of ice particles, the computed mean ice crystal size and IWC compare reasonably well with the measured mean values. The temperature dependence of ice crystal size and IWC has important climatic implications in that the temperature field perturbed by external radiative forcings, such as greenhouse warming, can alter the composition of ice crystal clouds. Through radiative transfer, ice microphysics can in turn affect the temperature field. Higher IWC would increase cloud solar albedo and infrared emissivity, while for a given IWC, larger crystals would reduce cloud albedo and emissivity. The competing effects produced by greenhouse temperature perturbations via ice micro-physics and radiation interactions and feedbacks are assessed by a one-dimensional radiative-convective climate model that includes an advanced radiation parameterization program. 3 figs.

  17. Green buildings: Implications for acousticians

    Science.gov (United States)

    Noble, Michael R.

    2005-04-01

    This presentation will deal with the practical implications of green design protocols of the US Green Building Council on interior acoustics of buildings. Three areas of particular consequence to acousticians will be discussed. Ventilation Systems: reduced energy consumption goals dictate reliance on natural cooling and ventilation using ambient air when possible. The consequent large openings in the building envelope to bring fresh air into rooms, and similar sized openings to transfer the mixed air out, can severely compromise the noise isolation of the rooms concerned. Radiant Cooling: the heavy concrete floors of buildings can be used as a thermal flywheel to lessen the cooling load, which forces the concrete ceilings to be exposed to the occupied rooms for heat transfer, and strictly limits the application of acoustical absorption on the ceilings. This challenges the room acoustics design. Green Materials: the LEED protocols require the elimination of potentially harmful finishes, including fibrous materials which may impact air quality or contribute to health problems. Since the backbone of sound absorption is glass and mineral fibres, this further challenges provision of superior room acoustics. Examples and commentary will be provided based on current and recent projects.

  18. Predictive implications of Gompertz's law

    Science.gov (United States)

    Richmond, Peter; Roehner, Bertrand M.

    2016-04-01

    Gompertz's law tells us that for humans above the age of 35 the death rate increases exponentially with a doubling time of about 10 years. Here, we show that the same law continues to hold up to age 106. At that age the death rate is about 50%. Beyond 106 there is so far no convincing statistical evidence available because the number of survivors are too small even in large nations. However, assuming that Gompertz's law continues to hold beyond 106, we conclude that the mortality rate becomes equal to 1 at age 120 (meaning that there are 1000 deaths in a population of one thousand). In other words, the upper bound of human life is near 120. The existence of this fixed-point has interesting implications. It allows us to predict the form of the relationship between death rates at age 35 and the doubling time of Gompertz's law. In order to test this prediction, we first carry out a transversal analysis for a sample of countries comprising both industrialized and developing nations. As further confirmation, we also develop a longitudinal analysis using historical data over a time period of almost two centuries. Another prediction arising from this fixed-point model, is that, above a given population threshold, the lifespan of the oldest persons is independent of the size of their national community. This prediction is also supported by empirical evidence.

  19. Predictive implications of Gompertz's law

    CERN Document Server

    Richmond, Peter

    2015-01-01

    Gompertz's law tells us that for humans above the age of 35 the death rate increases exponentially with a doubling time of about 10 years. Here, we show that the same law continues to hold even for ages over 100. Beyond 106 there is so far no statistical evidence available because the number of survivors is too small even in the largest nations. However assuming that Gompertz's law continues to hold beyond 106, we conclude that the mortality rate becomes equal to 1 at age 120 (meaning that there are 1,000 deaths in a population of one thousand). In other words, the upper bound of human life is near 120. The existence of this fixed-point has interesting implications. It allows us to predict the form of the relationship between death rates at age 35 and the doubling time of Gompertz's law. In order to test this prediction, we first carry out a transversal analysis for a sample of countries comprising both industrialized and developing nations. As further confirmation, we also develop a longitudinal analysis usi...

  20. Implications of zero economic growth

    Energy Technology Data Exchange (ETDEWEB)

    Thurow, L.C.

    1977-01-01

    The consequences of a zero economic growth (ZEG) policy are examined to see what limits to growth, some of which already exist, are desirable and what changes in our institutions are required to impose a no-growth policy. Past periods of zero or negative growth have increased unemployment, raised employability standards, and increased income-distribution inequalities with a subsequent lowering of the living standard. Zero population growth would offset this somewhat by freeing the capital now spent on education and career training and using it to raise per capita living standards if a work-sharing and unemployment-payment system were devised. Undesirable social implications would be felt both if a lack of employment opportunities reduced competition and consumption habits or if it led to intensive competition. Advocates of ZEG propose to restrain only those areas using nonrenewable resources and causing pollution of the environment, while expanding the service areas. The service sector (e.g., transportation and utilities) is also polluting and uses nonrenewable resources, however, pointing up their failure to account for indirect consumption. Many undeveloped countries already have ZEG but would not be content for the U.S. to halt growth opportunities. ZEG would be difficult to enforce and would do nothing to promote pollution control. (DCK)

  1. Knowledge Sharing and Implications to Employee Engagement

    OpenAIRE

    Abrar

    2011-01-01

    The objectives to be achieved in this research was to determine the application of knowledge sharing on the lecturers in Economics Faculty UNPAD, and knowing whether the lecturers are engaged or not, and determining the implications of knowledge sharing in employee engagement. This is an empirical study using description and verification methods with two variables. The implications of knowledge sharing to employee engagement includes the conditions of application of knowledge sharing, and the...

  2. Vague Congruences and Quotient Lattice Implication Algebras

    Directory of Open Access Journals (Sweden)

    Xiaoyan Qin

    2014-01-01

    Full Text Available The aim of this paper is to further develop the congruence theory on lattice implication algebras. Firstly, we introduce the notions of vague similarity relations based on vague relations and vague congruence relations. Secondly, the equivalent characterizations of vague congruence relations are investigated. Thirdly, the relation between the set of vague filters and the set of vague congruences is studied. Finally, we construct a new lattice implication algebra induced by a vague congruence, and the homomorphism theorem is given.

  3. Economic and policy implications of pandemic influenza.

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Braeton J.; Starks, Shirley J.; Loose, Verne W.; Brown, Theresa Jean; Warren, Drake E.; Vargas, Vanessa N.

    2010-03-01

    Pandemic influenza has become a serious global health concern; in response, governments around the world have allocated increasing funds to containment of public health threats from this disease. Pandemic influenza is also recognized to have serious economic implications, causing illness and absence that reduces worker productivity and economic output and, through mortality, robs nations of their most valuable assets - human resources. This paper reports two studies that investigate both the short- and long-term economic implications of a pandemic flu outbreak. Policy makers can use the growing number of economic impact estimates to decide how much to spend to combat the pandemic influenza outbreaks. Experts recognize that pandemic influenza has serious global economic implications. The illness causes absenteeism, reduced worker productivity, and therefore reduced economic output. This, combined with the associated mortality rate, robs nations of valuable human resources. Policy makers can use economic impact estimates to decide how much to spend to combat the pandemic influenza outbreaks. In this paper economists examine two studies which investigate both the short- and long-term economic implications of a pandemic influenza outbreak. Resulting policy implications are also discussed. The research uses the Regional Economic Modeling, Inc. (REMI) Policy Insight + Model. This model provides a dynamic, regional, North America Industrial Classification System (NAICS) industry-structured framework for forecasting. It is supported by a population dynamics model that is well-adapted to investigating macro-economic implications of pandemic influenza, including possible demand side effects. The studies reported in this paper exercise all of these capabilities.

  4. Results of Associated Implication Algebra on a Partial Ordered Set

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Some sufficient and necessary conditions that implication algebra on a partial ordered set is associated implication algebra are obtained, and the relation between lattice H implication algebra and associated implication algebra is discussed. Also, the concept of filter is proposed with some basic properties being studied.

  5. Rough Implication%粗糙蕴涵

    Institute of Scientific and Technical Information of China (English)

    薛占熬; 何华灿

    2003-01-01

    Rough implication operator is the emphasis and difficulty in the study of rough logic. Due to the shortage of rough implication in [3]~[5], we redefine rough set and rough implication operator by Stone algebra, and introduce new rough operators such as rough intersection, rough union, and rough complement. Moreover the characteristics of the proposed rough implication are investigated ,and we also point out that the proposed implication operation is superior to that of three-valued Lukasiewicz logic.

  6. Variscan Oroclines: Implications for Pangea

    Science.gov (United States)

    Johnston, S. T.

    2012-12-01

    The supercontinent Pangea is commonly interpreted to have formed in the Upper Carboniferous as a result of collision of Gondwana and Laurussia. The western European Variscan Orogen is interpreted as the product of the Gondwana - Laurussia continental collision. In Iberia, the Variscan Orogen describes two coupled Early Permian oroclines; a northern, convex to the west Cantabrian orocline, and a southern, convex to the east Central Iberian orocline. Palinspastic restoration of the oroclines using paleomagnetic, structural and stratigraphic constraints yield a 2300 km long, linear orogen that: (1) consists of a west-facing lower Paleozoic passive margin sequence of Gondwanan affinity; (2) is characterized by an east-verging thrust belt that passes east into Carboniferous foreland basin sequences and west into a metamorphic hinterland; (3) is bound to the west by ophiolite and juvenile oceanic arc sequences obducted over the the distal west edge of the passive margin along east-verging thrust faults; (4) has syn- to post-kinematic granitic intrusions that young from 330 in the west to 290 in the east; and (5) is, in the east, characterized by sedimentary and volcanic sequences of Avalonian (Meguma) affinity which are separated from the passive margin sequence by a marginal basin ophiolite. This tectonic template can be used to interpret the Variscan orogen across all of western Europe, and shows that the orogen consists of a >7000 km long ribbon that extends from Cornwall, SW England, east along a north-verging northern limb, around the Bohemian orocline in the east into a south-verging southern limb that runs along the Mediterranean into the Iberian oroclines. The implication of this geometry is that: (1) Variscan orogenesis consisted of the Carboniferous collision of a juvenile oceanic arc with a Gondwanan-affinity ribbon continent and the related collapse of a marginal basin that separated the passive margin from Avalonian lithosphere; followed by (2) buckling of

  7. First Record on Larval Development of the Cirripedian Parasite Loxothylacus texanus (Cirripedia-Rhizocephala Under Laboratory Conditions in Mxico

    Directory of Open Access Journals (Sweden)

    J. Franco-Lopez

    2006-01-01

    Full Text Available Crabs with mature parasites were put on individual aquariums of 20 L of capacity and with an initial salinity of 10. Salinity was gradually increased 1 until it reached a point in which parasites expeled their eggs or larvae. Larvae at different developmental stages obtained from each sample were preserved in 70 and ethanol to be studied afterwards. From 20 crabs employed, only 14 of them produced eggs and other 6 died after a few days at the aquariums. The mature externas expelled from 8000 to 160000 clustered eggs. After 24 h from the beginning of cellular division, larvae hatch. This larvae are called nauplius 1. This stage lasted 24 h, after which all larvae entered an excitation period, where they rapidly moved, to then pass a new molt process resulting in a new larval stage, nauplius 2. Elevating salinity a unity, externas started to expel eggs, nauplis larvae 1 hatched from them, but they only survived less than 24 h. As salinity increased, nauplius larvae lived longer, even to realized a molt. At a 15 salinity, larvae reached cypris stage with no problem, but with a salinity higher than 25, larvae died after a few hours of hatching. We can conclude that: the rhizocephalan Loxothylacus texanus has two nauplius stages, the nauplius and cypris larvae presented similar morphological characteristics to related species of rhizocephalans and a salinity interval from 15 to 20 report the same result.

  8. Cypris metamorphosis, injection and earliest internal development of theRrizocephalan Loxothylacus panopaei (Gissler). Crustacea: Cirripedia: Rhizocephala: Sacculinidae

    DEFF Research Database (Denmark)

    Glenner, H

    2001-01-01

    , and the succeeding developmental stages up to the stage of the earliest primordium reported from the literature. The anlage of the ovary is traced back to the free-swimming cypris stage and it is implied that the mesoderm and ectoderm of the endoparasite are already differentiated in the cyprid....

  9. Clinical Implications of Incomplete Pancreas Divisum

    OpenAIRE

    Terumi Kamisawa; Yuyang Tu; Naoto Egawa; Kouji Tsuruta; Aatsutake Okamoto

    2006-01-01

    Context Incomplete pancreas divisum is a pancreatic anomaly that results in an inadequate communication between the ventral and dorsal pancreatic ducts. Although the relationship between complete pancreas divisum and pancreatitis has been contentious, clinical implications of incomplete pancreas divisum have not been noted. Objective This study was done to investigate the clinical significance of incomplete pancreas divisum. Patients and...

  10. Insulin-Dependent Diabetes Mellitus: Educational Implications.

    Science.gov (United States)

    Yousef, Jamal M. S.

    1995-01-01

    This article provides an overview of the educational implications of diabetes in children through discussion of the nature of diabetes, factors associated with educational performance, and the teacher's role in meeting the child's needs. It argues that teachers should treat these students as normal learners, without ignoring their unique needs or…

  11. The nuclear and its psychological implications

    International Nuclear Information System (INIS)

    From the 13. to 15. january 1977, the S.F.R.P. has organised at Paris, with the patronage of The National Institute of Health and Medical Research, the French Society of Radiology, a colloquium devoted to the nuclear and its psycho-implications sociological. It is a second edition, realised at the demand of the Antoine Beclere Center. (N.C.)

  12. Implication of SLA to ELT in China

    Institute of Scientific and Technical Information of China (English)

    赵芸霞

    2016-01-01

    Second language acquisition, or SLA, is the processes by which people learn languages in addition to their native tongue(s). Although the theories can not be directly used to solve the practical problems, they do have great significance to language teaching. This paper mainly discusses the implication of Krashen' SLA theory and offers some reference opinions to English teaching in China.

  13. Genetic Counseling: Ethical and Professional Role Implications.

    Science.gov (United States)

    Witmer, J. Melvin; And Others

    1986-01-01

    Genetic counseling assists people in identifying potential or manifest genetic problems, understanding their implications, making decisions about what course to follow, and working through psychological and social aspects as they affect individuals or couples. Four ethical principles and related ethical issues pertaining to autonomy, beneficence…

  14. Brexit: what are the implications for nurses?

    Science.gov (United States)

    2016-06-29

    The referendum result is in and appears to have caught the nation by surprise. Whatever the fallout from voters' decision to leave the EU, the implications for nursing are likely to be widespread and profound - and could take years to resolve. PMID:27353892

  15. Ritalin Update: Implications for Reading Teachers.

    Science.gov (United States)

    Cotter, Robert B., Jr.; Werner, Patrice Holden

    1987-01-01

    Investigates how Ritalin, a powerful stimulant drug frequently prescribed for children exhibiting hyperactive behavior, poor attention span, and/or distractibility, is prescribed for children in educational settings, what doses seem appropriate, and what effect Ritalin has on reading achievement. Discusses the implications of Ritalin research for…

  16. Cult Affiliation and Disaffiliation: Implications for Counseling.

    Science.gov (United States)

    Robinson, Beth; Frye, Ellen M.; Bradley, Loretta J.

    1997-01-01

    Data on cult membership and the characteristics of cults are provided. The process of cult affiliation and its relationship to family dynamics are reviewed. Defection, the processes of disaffiliation (voluntary and involuntary), and clinical symptoms after cult disaffiliation are discussed. Implications and recommendations for counselors are…

  17. Supervision and Motivational Theory: Some Implications.

    Science.gov (United States)

    Reyes, Donald J.

    1982-01-01

    Suggests useful implications for supervisors offered by motivational theories, including the importance of serving as a source of reinforcement for teachers and the necessity of helping the teacher make appropriate instructional choices and gather evidence on the effectiveness of those choices. (Author/JM)

  18. Some Implications of Human-Structure Interaction

    DEFF Research Database (Denmark)

    Pedersen, Lars

    2013-01-01

    On structures, humans may be active which may cause structural vibrations as human activity can excite structural vibration modes. However, humans may also be passive (sitting or standing on the structure). The paper addresses this subject and explores the implications of having passive humans...

  19. Brexit: what are the implications for nurses?

    Science.gov (United States)

    2016-06-29

    The referendum result is in and appears to have caught the nation by surprise. Whatever the fallout from voters' decision to leave the EU, the implications for nursing are likely to be widespread and profound - and could take years to resolve.

  20. Teacher's Experiences in PBL: Implications for Practice

    Science.gov (United States)

    Alves, Anabela C.; Sousa, Rui M.; Fernandes, Sandra; Cardoso, Elisabete; Carvalho, Maria Alice; Figueiredo, Jorge; Pereira, Rui M. S.

    2016-01-01

    Project-Based Learning (PBL) has been implemented in the first year of the Industrial Engineering and Management programme at the University of Minho, Portugal, since 2004/2005. The purpose of this paper is to analyse and discuss teachers' experiences in PBL in this programme and to explore its implications for student learning and for teaching…

  1. Linguistic Truth Values Lattice Implication Algebras

    Institute of Scientific and Technical Information of China (English)

    PAN Xiao-dong; XU Yang

    2006-01-01

    In order to study uncertainty reasoning and automatic reasoning with linguistic terms, in this paper, the set of basic linguistic truth values and the set of modifiers are defined, according to common sense; partially orderings are defined on them. Based on it, a lattice implication algebra model L18 of linguistic terms is built; furthermore, its some basic properties are discussed.

  2. Corporal Punishment: Legalities, Realities, and Implications.

    Science.gov (United States)

    Hinchey, Patricia H.

    2003-01-01

    Presents a quiz that will help readers determine the reliability of their own perceptions relating to corporal punishment in schools. Discusses U.S. Courts and corporal punishment, worldwide and nationwide legality, and the realities of corporal punishment in the United States. Discusses implications for what teachers can do to address corporal…

  3. Biological Implications of Gene-Environment Interaction

    Science.gov (United States)

    Rutter, Michael

    2008-01-01

    Gene-environment interaction (G x E) has been treated as both a statistical phenomenon and a biological reality. It is argued that, although there are important statistical issues that need to be considered, the focus has to be on the biological implications of G x E. Four reports of G x E deriving from the Dunedin longitudinal study are used as…

  4. Changing business environment: implications for farming

    OpenAIRE

    Malcolm, Bill

    2011-01-01

    The natural, technological, economic, political and social environment in which farmers farm constantly changes. History has lessons about change in agriculture and about farmers coping with change, though the future is unknowable and thus always surprising. The implication for farm operation is to prepare, do not predict.

  5. Commentary: Pedagogical Implications of Experimental SNS Research

    Science.gov (United States)

    Carreira, Maria; Potowski, Kim

    2011-01-01

    This special issue of the "Heritage Language Journal", guest edited by Silvina Montrul, unites four papers on different aspects of heritage Spanish speakers' linguistic abilities. In this commentary, we reexamine these important contributions with an eye toward implications for instruction and toward general trends for the field. In particular, we…

  6. Educational Implications of Microelectronics and Microprocessors.

    Science.gov (United States)

    Harris, N. D. C., Ed.

    This conference report explores microelectronic technology, its effect on educational methods and objectives, and its implications for educator responsibilities. Two main areas were considered: the significance of the likely impact of the large scale introduction of microprocessors and microelectronics on commercial and industrial processes, the…

  7. Ambiguity and Volatility : Asset Pricing Implications

    NARCIS (Netherlands)

    Pataracchia, B.

    2011-01-01

    Using a simple dynamic consumption-based asset pricing model, this paper explores the implications of a representative investor with smooth ambiguity averse preferences [Klibano¤, Marinacci and Mukerji, Econometrica (2005)] and provides a comparative analysis of risk aversion and ambiguity aversion.

  8. Physical implications of dynamical symmetry breaking

    International Nuclear Information System (INIS)

    Some model-independent physical implications of a class of hypercolorbased theories of dynamical symmetry-breaking are described and discussed. The role which e+e- colliders can play, in distinguishing between such theories and the canonical methodology, is underlined

  9. Theoretical, regulatory and practical implications of logistics

    Directory of Open Access Journals (Sweden)

    Mirosław Chaberek

    2014-03-01

    Full Text Available Background: The logistics has its practical input in creating economical strategies as well as in creating modern economic environment. Processes of planning, designing and functioning of logistic systems must be based both on the theoretical knowledge covering various areas as well as practical experiences to provide the required support.  To provide logistic services in the rational way, it is necessary to learn the complicated set of implications resulting from three areas covering the theoretical knowledge, practical ones as well as the regulation by the law. Methods: The triad of three concepts: theory, practice and regulation is the main area of consideration in relation to tasks of the logistic support provided by any organization for any production process. The aim of this paper focuses on the necessity of taking into account implications among theory, practice and regulation during the process of analyzing, designing and implementation of systems of the logistic support. The lack of awareness of differences between various implications or ignoring them must lead to irrational behaviors. Results: The implications among theory, practice and legislative regulation of logistics presented differently than usually, broaden the logistic knowledge and at the same time provide the tool of the rationalization of logistic services in all kinds of activities. Conclusions: The correct identification of tasks and functions of the logistics leads to the recognition of its subject and tasks and correct identification of implications occurring among theory, practice and regulation. This knowledge is indispensable in the process of creation of projects of logistic services of each activity, both business and non-business one.

  10. Rejoinder--Implications of "Online Display Advertising: Targeting and Obtrusiveness"

    OpenAIRE

    Avi Goldfarb; Catherine Tucker

    2011-01-01

    The commentaries on our work suggest several broader implications of our findings as well as a concern that we understate the size of the effect. In this rejoinder, we discuss our views on the regulatory implications, the implications for firm strategies, and the implications for our understanding of the underlying behavioral processes. We also acknowledge that our original calculation of $464 million in cost savings for industry is conservative. We conclude with a call for "privacy engineeri...

  11. Sleep disorders in Pregnancy: Glycaemic implications.

    Science.gov (United States)

    Kumar, K V S Hari

    2016-09-01

    Sleep is one of the essential biorhythms of the body that helps in optimum restoration of many body functions. The sleep-wake cycle is determined by the circadian centre and is responsible for the anabolic functions in the body. Infants require about 14 to 18 hours of sleep per day, which reduces gradually to about 8 hours in adults. Urbanization and evolutionary changes have altered the sleep hygiene and shortened the sleep duration. This lead to various sleep disorders like sleep disordered breathing, insomnia and narcolepsy. Sleep disorders lead to adverse cardio-metabolic consequences, including insulin resistance and hyperglycaemia. Pregnancy poses an enormous burden on the homeostasis of the women with alteration in many physiological functions. The sleep disorders during pregnancy lead to adverse foeto-maternal outcomes with long term cardiovascular implications. In this article, I review the pathophysiology of sleep disorders during pregnancy and their glycaemic implications. PMID:27582156

  12. Mirror neurons: their implications for group psychotherapy.

    Science.gov (United States)

    Schermer, Victor L

    2010-10-01

    Recently discovered mirror neurons in the motor cortex of the brain register the actions and intentions of both the organism and others in the environment. As such, they may play a significant role in social behavior and groups. This paper considers the potential implications of mirror neurons and related neural networks for group therapists, proposing that mirror neurons and mirror systems provide "hard-wired" support for the group therapist's belief in the centrality of relationships in the treatment process and exploring their value in accounting for group-as-a-whole phenomena. Mirror neurons further confirm the holistic, social nature of perception, action, and intention as distinct from a stimulus-response behaviorism. The implications of mirror neurons and mirroring processes for the group therapist role, interventions, and training are also discussed.

  13. Teacher's experiences in PBL: implications for practice

    Science.gov (United States)

    Alves, Anabela C.; Sousa, Rui M.; Fernandes, Sandra; Cardoso, Elisabete; Carvalho, Maria Alice; Figueiredo, Jorge; Pereira, Rui M. S.

    2016-03-01

    Project-Based Learning (PBL) has been implemented in the first year of the Industrial Engineering and Management programme at the University of Minho, Portugal, since 2004/2005. The purpose of this paper is to analyse and discuss teachers' experiences in PBL in this programme and to explore its implications for student learning and for teaching practices in higher education. For data collection, the research method used was written narratives to these teachers, at the end of the PBL semester. Findings suggest that teachers express a positive view of PBL as a learning approach. They identify student motivation and engagement, along with a better understanding of the application of concepts in real-life situations, as important outcomes of the project for students. Besides this, teachers also highlight the importance of the development of transversal skills by students throughout the project. Recommendations for future work and implications for practice will also be discussed.

  14. Learning and reconsolidation implicate different synaptic mechanisms.

    Science.gov (United States)

    Li, Yan; Meloni, Edward G; Carlezon, William A; Milad, Mohammed R; Pitman, Roger K; Nader, Karim; Bolshakov, Vadim Y

    2013-03-19

    Synaptic mechanisms underlying memory reconsolidation after retrieval are largely unknown. Here we report that synapses in projections to the lateral nucleus of the amygdala implicated in auditory fear conditioning, which are potentiated by learning, enter a labile state after memory reactivation, and must be restabilized through a postsynaptic mechanism implicating the mammalian target of rapamycin kinase-dependent signaling. Fear-conditioning-induced synaptic enhancements were primarily presynaptic in origin. Reconsolidation blockade with rapamycin, inhibiting mammalian target of rapamycin kinase activity, suppressed synaptic potentiation in slices from fear-conditioned rats. Surprisingly, this reduction of synaptic efficacy was mediated by post- but not presynaptic mechanisms. These findings suggest that different plasticity rules may apply to the processes underlying the acquisition of original fear memory and postreactivational stabilization of fear-conditioning-induced synaptic enhancements mediating fear memory reconsolidation. PMID:23487762

  15. Growth Laws in Cancer: Implications for Radiotherapy

    CERN Document Server

    Castorina, P; Gabriele, P; Guiot, C

    2006-01-01

    Comparing both, the more conventional Gompertz tumor growth law (GL) and the ``Universal'' law (UL), recently proposed and applied to cancer,we have investigated the growth law's implications on various radiotherapy regimen. According to GL, the surviving tumor cell fraction could be reduced 'ad libidum', independently of the initial tumor mass,simply by increasing the number of treatments. On the contrary, if tumor growth dynamics would indeed follow the Universal scaling law, there is a lower limit of the survival fraction that cannot be reduced any further regardless of the total number of treatments. This finding can explain the so called ``tumor size effect'' and re-emphasizes the importance of early diagnosis as it implies that radiotherapy may be successful provided the tumor mass at treatment onset is rather small. Taken together with our previous works, implications of these findings include revisiting standard radiotherapy regimen and overall treatment protocols.

  16. Implications of macro-areal linguistics

    Directory of Open Access Journals (Sweden)

    Corinna Leschber

    2015-09-01

    Full Text Available Implications of macro-areal linguisticsUsing the examples of some Balkan words with a difficult etymology, we attempt to show the possibilities for and implications of applying a macro-areal linguistic perspective to establish a wider view of the linguistic and cultural history of a region. Implikacje językoznawstwa makroarealnegoNa przykładzie niektórych bałkańskich słów o skomplikowanej etymologii autorka dokonuje próby pokazania możliwości i potencjału badawczego perspektywy makroarealnej. W każdym wypadku daje ona głębszy wgląd w historię, rozwój językowy i kulturowy tego regionu.

  17. Implications of LHC Searches for Massive Graviton

    CERN Document Server

    Tang, Yong

    2012-01-01

    With the latest LHC available results, we consider the generic constraints on massive graviton. Both dijet and dilepton resonance searches are used. The limits on parameter space can be applied to many models. As an illustration, we show the constraints for Randall-Sundrum (RS) model. Implications on massive graviton and the coupling strength are discussed. For $k/M_{pl}=0.1$, $M_G<2.2$ TeV region is excluded at 95% confidence level. We also present some interesting implications on the RS radion with respect to the 125 GeV excess at the LHC. For $k/M_{pl}=0.1$, $\\Lambda_\\phi<13.8$ TeV is excluded where $\\Lambda_\\phi$ is the scale to charactarize the interaction strengh of radion.

  18. ECONOMIC IMPLICATIONS OF INSUFFICIENT HEALTH LITERACY

    OpenAIRE

    Dukić, Nikolina; Arbula Blecich, Andrea; Cerović, Ljerka

    2013-01-01

    The main goal of this paper is to elaborate the importance of health literacy in cost-effective utilization of health care services which influence the efficiency of the entire health care sector. In order to complement the theoretical framework of the economic implications and the circular influence of health literacy on the economy, an empirical analysis was carried out using S–TOFHLA. The results suggest that the patients’ personal characteristics and the accessibil...

  19. The remnant CP transformation and its implications

    CERN Document Server

    Gonzalez-Canales, Felix

    2016-01-01

    In the context of remnant CP transformations, I briefly discuss a generalized $\\mu-\\tau$ reflection symmetry, where the "Majorana" phases have CP conserving values, which are directly related with the CP parities of neutrino states. Also, one finds that the "Dirac-like" CP violation phase is correlated with the atmospheric mixing angle, giving important phenomenological implications for current and future long baseline oscillation neutrino experiments.

  20. Social Implications of Neo - Imperialism in India

    OpenAIRE

    Dhas, Albert Christopher; Helen, Mary Jacqueline

    2010-01-01

    The globalisation process, which aimed at integration of economies and global development, is basically a reflection of neo-imperialism ideas. The question addressed in this paper is: what are the social implications of the neo-imperialism (globalisation) process in India, particularly on the social security aspects of the working population? Accordingly, an attempt is made in this paper to examine changes in the social security status of the working population that have been brought ab...

  1. Thalamocortical synchronization and cognition: implications for schizophrenia?

    OpenAIRE

    Uhlhaas, Peter J.; Roux, Frederic; Singer, Wolf

    2013-01-01

    Cognitive deficits are a core dysfunction in schizophrenia. In this issue of Neuron, Parnaudeau et al. (2013) investigated synchronization in thalamocortical pathways in an animal model to address the disconnection between brain regions as a mechanism for working memory impairments in the disorder.implicated dysfunctional neural oscillations in the explanation of cognitive deficits and certain clinical symptoms of schizophrenia. Specifically, we will focus on findings that have examined neura...

  2. Molecular heterogeneity in glioblastoma: potential clinical implications

    Directory of Open Access Journals (Sweden)

    Nicole Renee Parker

    2015-03-01

    Full Text Available Glioblastomas, (grade 4 astrocytomas, are aggressive primary brain tumors characterized by histopathological heterogeneity. High resolution sequencing technologies have shown that these tumors also feature significant inter-tumoral molecular heterogeneity. Molecular subtyping of these tumors has revealed several predictive and prognostic biomarkers. However, intra-tumoral heterogeneity may undermine the use of single biopsy analysis for determining tumor genotype and has implications for potential targeted therapies. The clinical relevance and theories of tumoral molecular heterogeneity in glioblastoma are discussed.

  3. Aggregate Implications of Micro Asset Market Segmentation

    OpenAIRE

    Chris Edmond; Pierre-Olivier Weill

    2011-01-01

    This paper develops a consumption-based asset pricing model to explain and quantify the aggregate implications of a frictional financial system, comprised of many financial markets partially integrated with one another. Each of our micro financial market's is inhabited by traders who are specialized in that markets type of asset. We specify exogenously the level of segmentation that ultimately determines how much idiosyncratic risk traders bear in their micro market and derive aggregate asset...

  4. Bioavailability: implications for science/cleanup policy

    Energy Technology Data Exchange (ETDEWEB)

    Denit, Jeffery; Planicka, J. Gregory

    1998-12-01

    This paper examines the role of bioavailability in risk assessment and cleanup decisions. Bioavailability refers to how chemicals ''behave'' and their ''availability'' to interact with living organisms. Bioavailability has significant implications for exposure risks, cleanup goals, and site costs. Risk to human health and the environment is directly tied to the bioavailability of the chemicals of concern.

  5. Breast cancer heterogeneity: mechanisms, proofs, and implications

    OpenAIRE

    Yi-Hsuan Hsiao, Ming-Chih Chou, Carol Fowler, Jeffrey T. Mason, Yan-gao Man

    2010-01-01

    Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically distinct subtypes with substantially different molecular and/or biochemical signatures, clinical courses, and prognoses. This study analyzed the possible correlation between the morphological presentations of breast cancer and two hypothesized models of carcinogenesis, in order to identify the intrinsic mechanism(s) and clinical implications of breast cancer heterogeneity.

  6. Breast cancer heterogeneity: mechanisms, proofs, and implications

    Directory of Open Access Journals (Sweden)

    Yi-Hsuan Hsiao, Ming-Chih Chou, Carol Fowler, Jeffrey T. Mason, Yan-gao Man

    2010-01-01

    Full Text Available Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically distinct subtypes with substantially different molecular and/or biochemical signatures, clinical courses, and prognoses. This study analyzed the possible correlation between the morphological presentations of breast cancer and two hypothesized models of carcinogenesis, in order to identify the intrinsic mechanism(s and clinical implications of breast cancer heterogeneity.

  7. FEMALE URETHRA – ANATOMO-CLINICAL IMPLICATIONS

    OpenAIRE

    C. Zanoschi; R. Moldovanu

    2006-01-01

    Urethra represents the last segment of the urinary tract. We present a comprehensive account of the female urethral anatomy, including its component structures, neurovascular supply, relationship to adjacent structures (the vagina, bladder and vestibular glands, and connective tissue supports) and histology. These data are important because the distal segment of the female urethra is implicated in the mechanism of urinary continence (female stress urinary incontinence is thought to result f...

  8. Implications of Theoretical Ideas Regarding Cold Fusion

    OpenAIRE

    Abbas, Afsar

    1995-01-01

    A lot of theoretical ideas have been floated to explain the so called cold fusion phenomenon. I look at a large subset of these and study further physical implications of the concepts involved. I suggest that these can be tested by other independent physical means. Because of the significance of these the experimentalists are urged to look for these signatures. The results in turn will be important for a better understanding and hence control of the cold fusion phenomenon.

  9. 2014 and beyond: implications for displacement

    Directory of Open Access Journals (Sweden)

    Aidan O’Leary

    2014-05-01

    Full Text Available 2014 marks a watershed for Afghanistan, with the withdrawal of the International Security Assistance Force after twelve years, and the very real risks this withdrawal poses to the capacity of the Afghan state to meet the many internal and external challenges faced by the country. These challenges have significant implications for displaced and returning Afghans and for the potential for displacement in the future.

  10. Environment Implications of China's WTO Accession

    Institute of Scientific and Technical Information of China (English)

    Li Shantong; He Jianwu

    2006-01-01

    China's WTO accession will have important environmental implications. This article aims at providing environmental analysis of the impact of China's accession to the WTO, based on its final offer for WTO accession and a 53-sector, recursive dynamic computable general equilibrium (CGE) model of China. We try to provide some empirical evidences for policy makers to evaluate the effects of China's WTO accession from environmental prospective.

  11. On the normative implications of social neuroscience

    OpenAIRE

    Arleen Salles

    2013-01-01

    Within the last decades, brain science has been offering new insights into the relationship among diverse psychological processes and the neural correlates of our moral thought and behavior. Despite the distinction between the explanatory/descriptive nature of science and the normative nature of morality, some neuroethicists have claimed that neuroscientific findings have normative implications. In this paper, I identify three interpretations of the claim. The first focuses on neuroscience’s ...

  12. Investigating Variations in Gameplay: Cognitive Implications

    Directory of Open Access Journals (Sweden)

    Kamran Sedig

    2015-01-01

    Full Text Available There is increasing interest in creating computer games for learning, problem solving, and other high-level cognitive activities. When investigating whether gameplay is conducive to such activities, gameplay is often studied as a whole. As a result, cognitive implications can be linked to the game but not to its structural elements. Given that gameplay arises from interaction between the player and the game, it is the structural components of interaction that should be investigated to better understand the design of gameplay. Furthermore, minor variations in the components of interaction can have significant cognitive implications. However, such variation has not been studied yet. Thus, to gain a better understanding of how we can study the effect of interaction on the cognitive aspect of gameplay, we conducted an exploratory investigation of two computer games. These games were isomorphic at a deep level and only had one minor difference in the structure of their interaction. Volunteers played these games and discussed the cognitive processes that emerged. In one game, they primarily engaged in planning, but in the other game they primarily engaged in visualizing. This paper discusses the results of our investigation as well as its implications for the design of computer games.

  13. Reproductive effort of both male and female bar-throated Apalis apalis thoracica is predicted by ornamentation of self and mate

    NARCIS (Netherlands)

    van Dijk, Rene E.; Robles, Raquel; Groothuis, Ton G. G.; de Vries, Bonnie; Eising, Corine M.

    2015-01-01

    Melanin-based plumage ornaments have been shown to play an important role in male-male competition, but also influence inter-sexual communication. Consequently, ornaments may be associated with reproductive effort of both males and females. Females mated to males with larger melanin ornaments may ac

  14. GLOBAL WARMING: IMPLICATIONS AND ANTICIPATORY ADAPTIVE MEASURES

    Directory of Open Access Journals (Sweden)

    MUNESH KUMAR

    2011-12-01

    Full Text Available Our earth is warming up. There is no denying to this fact that the gradual heating up of our globe has a tremendous effect on the climate. It in turn has affected the biotic factors that make up our biosphere, eventually directing the course of our socio-economic development. Some workers are, however, optimistic about this natural phenomenon. Various ways have been suggested to mitigate the effects of global warming, but the damage already done cannot be revoked. Hence, the thing that we are left with is to go for anticipatory adaptive measures so as to tone down the intensity of future implications of global warming.

  15. Ionization potentials some variations, implications and applications

    CERN Document Server

    Ahrens, L H

    1983-01-01

    Ionization Potentials: Some Variations, Implications and Applications covers several aspects of ionization potential that is a highly significant parameter in controlling the properties of electric discharge. Comprised of 17 chapters, the book covers topic relevant to ionization potentials, such as properties, concepts, and applications, in order to understand and fully comprehend all aspects of ionization potential. The opening chapter is a review of ionization potentials and a discussion of trends and features. The succeeding chapters then tackle complex topics such as the s and p electrons;

  16. Professional socialization: implications for occupational therapy education.

    Science.gov (United States)

    Sabari, J S

    1985-02-01

    This article examines the implications that adult socialization theory can have on occupational therapy education. Sociological literature about professional socialization is reviewed and related to the preparation of occupational therapists. The discussion includes a description of the goals, processes, and participants in professional socialization. Consistency of socializing influences is presented as a critical factor in the formation of strong professional role identities. Finally, the article considers which values and attitudes may be transmitted during the socialization process for occupational therapists and other health professionals. PMID:3976829

  17. Adolescent Health Implications of New Age Technology.

    Science.gov (United States)

    Jacobson, Cara; Bailin, Alexandra; Milanaik, Ruth; Adesman, Andrew

    2016-02-01

    This article examines the health implications of new age technology use among adolescents. As Internet prevalence has increased, researchers have found evidence of potential negative health consequences on adolescents. Internet addiction has become a serious issue. Pornography is now easily accessible to youth and studies have related pornography with several negative health effects. Cyberbullying has become a large problem as new age technologies have created a new and easy outlet for adolescents to bully one another. These technologies are related to increased morbidity and mortality, such as suicides due to cyberbullying and motor vehicle deaths due to texting while driving. PMID:26613696

  18. Massive neutron stars and their implications

    Indian Academy of Sciences (India)

    T K Jha; Keshab C Panda

    2014-05-01

    Recent observations of high mass pulsar PSRJ1614-2230 has raised serious debate over the possible role of exotics in the dense core of neutron stars. The precise measurement of mass of the pulsar may play a very important role in limiting equation of state (EoS) of dense matter and its composition. Indirectly, it may also shape our understanding of the nucleon–hyperon or hyperon–hyperon interactions which is not well known. Within the framework of an effective chiral model, we compute models of neutron stars and analyse the hyperon composition in them. Further related implications are also discussed.

  19. Corporate Language and Implications for Organizational Learning

    DEFF Research Database (Denmark)

    Zølner, Mette

    2013-01-01

    is insufficient to leverage contextually specific and culturally embedded knowledge. This indicates the need for disentangling language and culture. The paper further argues for the need to go beyond national language to consider how prevailing kinds of corporate talk may curb headquarters potential for learning......This paper explores empirically implications of language use for MNCs’ learning from subsidiaries. Drawing on sociolinguistic literature, the article argues that while employing a single corporate language facilitates quick and direct communication of explicit knowledge, such a language design...... from cultural and contextual diversity....

  20. Implication-based fuzzy semiautomaton of a finite group and its properties

    Science.gov (United States)

    Selva Rathi, M.; Michael Anna Spinneli, J.

    2016-06-01

    Implication-based fuzzy semiautomaton (IBFSA) of a finite group is defined. The ideas of an implication-based fuzzy kernel and implication-based fuzzy subsemiautomaton of an IBFSA over a finite group are developed using the concept of implication-based fuzzy subgroup and implication-based fuzzy normal subgroup. The necessary and sufficient condition for the implication-based fuzzy kernel and implication-based fuzzy subsemiautomaton of an IBFSA and few other results are proved in this paper.

  1. A synopsis of collective alpha effects and implications for ITER

    Energy Technology Data Exchange (ETDEWEB)

    Sigmar, D.J.

    1990-10-01

    This paper discusses the following: Alpha Interaction with Toroidal Alfven Eigenmodes; Alpha Interaction with Ballooning Modes; Alpha Interaction with Fishbone Oscillations; and Implications for ITER.

  2. Forensic implications: adolescent sexting and cyberbullying.

    Science.gov (United States)

    Korenis, Panagiota; Billick, Stephen Bates

    2014-03-01

    Adolescence is marked by establishing a sense of identity, core values, a sense of one's relationship to the outside world and heightened peer relationships. In addition, there is also risk taking, impulsivity, self exploration and dramatic increase in sexuality. The dramatic increase in the use of cell phones and the Internet has additional social implications of sexting and cyberbullying. Sexting refers to the practice of sending sexually explicit material including language or images to another person's cell phone. Cyberbullying refers to the use of this technology to socially exclude, threaten, insult or shame another person. Studies of cell phone use in the 21st century report well over 50% of adolescents use them and that text messaging is the communication mode of choice. Studies also show a significant percentage of adolescents send and receive sex messaging, both text and images. This paper will review this expanding literature. Various motivations for sexting will also be reviewed. This new technology presents many dangers for adolescents. The legal implications are extensive and psychiatrists may play an important role in evaluation of some of these adolescents in the legal context. This paper will also make suggestions on future remedies and preventative actions.

  3. Forensic implications: adolescent sexting and cyberbullying.

    Science.gov (United States)

    Korenis, Panagiota; Billick, Stephen Bates

    2014-03-01

    Adolescence is marked by establishing a sense of identity, core values, a sense of one's relationship to the outside world and heightened peer relationships. In addition, there is also risk taking, impulsivity, self exploration and dramatic increase in sexuality. The dramatic increase in the use of cell phones and the Internet has additional social implications of sexting and cyberbullying. Sexting refers to the practice of sending sexually explicit material including language or images to another person's cell phone. Cyberbullying refers to the use of this technology to socially exclude, threaten, insult or shame another person. Studies of cell phone use in the 21st century report well over 50% of adolescents use them and that text messaging is the communication mode of choice. Studies also show a significant percentage of adolescents send and receive sex messaging, both text and images. This paper will review this expanding literature. Various motivations for sexting will also be reviewed. This new technology presents many dangers for adolescents. The legal implications are extensive and psychiatrists may play an important role in evaluation of some of these adolescents in the legal context. This paper will also make suggestions on future remedies and preventative actions. PMID:24129662

  4. Global implications of China's healthcare reform.

    Science.gov (United States)

    Yan, Fei; Tang, Shenglan; Zhang, Jian

    2016-01-01

    The ongoing healthcare reform in China has a powerful spillover effect beyond the health sector and the borders of China. A successful completion of the Chinese reform will offer a new model for social justice development, shift the global economy toward sustainability and create a new hub for science and technology in medical and health science. However, reforming the healthcare system in the most populated country is a daunting task. China will not live up to its promise, and all the potentials may end with hype not hope if coherent national strategies are not constructed and state-of-the-art navigation is not achieved with staggering domestic and global challenges. The cost of failure will be immensely high, socioeconomic costs for Chinese and an opportunity cost for the world as a whole. A full appreciation of the global implications of China's healthcare reform is crucial in keeping China receptive toward good practices evidence-approved elsewhere and open minded to fulfill its international obligations. More critically, the appreciation yields constructive engagements from global community toward a joint development and global prosperity. The current report provides a multiple disciplinary assessment on the global implications of the healthcare reform in China. PMID:24890392

  5. Abiding IPRs in Technological Implications for Pakistan

    Directory of Open Access Journals (Sweden)

    Murtaza Hussain Shaikh A

    2014-03-01

    Full Text Available The focal objective of this article is to analyze the role of intellectual property rights in technological implications within a general context. The performance of the IPRs system and its interaction with national innovation system with some degrees of success has also been highlighted. Major encounter over subsequently decade will be to identify policies and solutions that would permit marketplace economy to flourish in the framework of this intellectual property insurrection. There has been a lot of dispute on the role of intellectual property protection regime specially in fostering innovation, technology development of a country. IPRs are expected to emboli the innovation, by rewarding inventor with a grant of domination rights over the mercantile exploitation for a specified time period. This article tries to attempts to review the role of the IPR regime in technological development and also have suggested some policy implications for country like Pakistan and some reflecting lessons for other developing countries with similar settings and common characteristics. Keywords -

  6. L-型模糊格蕴涵代数%L-fuzzy Lattice Implication Algebra

    Institute of Scientific and Technical Information of China (English)

    宋庆龙; 李春瑞; 赵光峰

    2006-01-01

    This paper introduced the concept of L-fuzzy sub lattice implication algebra and discussed its properties. Proved that the intersection set of a family of L-fuzzy sub lattice implication algebras is a L-fuzzy sub lattice implication algebra, that a L-fuzzy sub set of a lattice implication algebra is a L-fuzzy sub lattice implication algebra if and only if its every cut set is a sub lattice implication algebra, and that the image and original image of a L-fuzzy sub lattice implication algebra under a lattice implication homomorphism are both L-fuzzy sub lattice implication algebras.

  7. Subdirectly Irreducible and Directly Indecomposable Lattice Implication Algebras

    Institute of Scientific and Technical Information of China (English)

    WANG Xue-fang; XU Yang; SONG Zhen-ming

    2004-01-01

    Lattice implication algebra is analgebraic structure that is established by combining lattice andimplicative algebra. It originated from the study onlattice-valued logic. In this paper, we characterize two specialclasses of lattice implication algebra, namely, subdirectlyirreducible and directly indecomposable lattice implicationalgebras. Some important results are obtained.

  8. Education System Reform in China after 1978: Some Practical Implications

    Science.gov (United States)

    Sun, Miantao

    2010-01-01

    Purpose: This paper aims to provide an overview of education system reform in China since 1978, and its practical implications. Design/methodology/approach: Data were collected from literature review and interview. An overview of education system reform and its practical implications was found through data analysis. Findings: There has been two…

  9. Motivation and Gifted Students: Implications of Theory and Research

    Science.gov (United States)

    Clinkenbeard, Pamela R.

    2012-01-01

    An analysis of contemporary motivation theories reveals implications for gifted and talented students. The expectancy-value framework, intrinsic-extrinsic motivation theories, goal orientations, self-efficacy and other self-perceptions, and attribution theory are described and discussed with respect to implications for the psychology and education…

  10. Local sustainable development – implications for local public finances

    OpenAIRE

    FLORIN OPREA; ELENA CIGU

    2012-01-01

    Local sustainable development implications on local public finances are complex because this phenomenon explained by development strategies mobilizes local resources towards achieving the three dimensions that define the phenomenon. This paper aims to develop these implications in Romania, showing that the local development strategy determines the reorganization of local government finances in identifying resources to cover expenses, which are directed towards achieving the goals.

  11. Macroeconomic and policy implications of population aging in Brazil

    OpenAIRE

    Jorgensen, Ole Hagen

    2011-01-01

    This paper analyzes the macroeconomic implications of population aging in Brazil. Three alternative yet complementary methodologies are adopted, and depending on policy responses to the fiscal implications of aging, there are two main findings: First, saving rates could increase and not necessarily fall as a consequence of aging in Brazil -- thus contradicting conventional views. Second, l...

  12. Implications of global warming on human health

    International Nuclear Information System (INIS)

    Due to the build up of green house gases in atmosphere, less heat escapes through the atmosphere promoting global warming. This may result in world wide droughts, sea-level rise inundating islands and coastal countries, cataclysmic hurricanes etc. Human health as a result of these changes, will be affected both physiologically and psychologically. Physiological effects may be more pronounced in cases occurring due to changes in rainfall and temperature patterns, food production amounts, water availability, etc. Psychological impact may be more in cases of catastrophes like floods, hurricanes or famine. In this paper, an attempt has been made to highlight the implications of global warming on human health due to temperature change. Food production changes and ultra-violet radiation effects and cataclysmic disaster effects. (author)

  13. Phonological development in young bilinguals: clinical implications.

    Science.gov (United States)

    Core, Cynthia; Scarpelli, Chiara

    2015-05-01

    This article reviews recent research on bilingual phonological development and describes the nature of bilingual phonology, focusing on characteristics of cross-linguistic influence on bilingual phonological abilities. There is evidence of positive and negative transfer (acceleration and deceleration) on children's phonological abilities. Several methodological issues limit the ability to generalize findings from previous research to larger groups of bilingual children (e.g., small sample size, lack of consideration of age of acquisition of each language, and language abilities of the participants). Sources of heterogeneity in language development are presented and discussed. Phonological abilities are related to language abilities in bilingual first language learners of English and Spanish. Empirical evidence from research in our laboratory supports this claim. We discuss implications of research findings and limitations for future research and clinical practice. We provide specific recommendations for bilingual research and for clinical assessment of young bilingual children.

  14. Prescription drug abuse: problem, policies, and implications.

    Science.gov (United States)

    Phillips, Janice

    2013-01-01

    This article provides an overview on prescription drug abuse and highlights a number of related legislative bills introduced during the 112th Congress in response to this growing epidemic. Prescription drug abuse has emerged as the nation's fastest growing drug problem. Although prescription drugs have been used effectively and appropriately for decades, deaths from prescription pain medicine in particular have reached epidemic proportions. Bills related to prescription drug abuse introduced during the 112th Congress focus on strengthening provider and consumer education, tracking and monitoring prescription drug abuse, improving data collection on drug overdose fatalities, combating fraud and abuse in Medicare and Medicaid programs, reclassifying drugs to make them more difficult to prescribe and obtain, and enforcing stricter penalties for individuals who operate scam pain clinics and sell pain pills illegitimately. This article underscores the importance of a multifaceted approach to combating prescription drug abuse and concludes with implications for nursing. PMID:23245611

  15. Destination image: Origins, Developments and Implications

    Directory of Open Access Journals (Sweden)

    Sérgio Dominique Ferreira Lopes

    2011-01-01

    Full Text Available Over the last few decades, tourism has become one of the main sectors of the global economy, not only because of its contribution to the Gross Domestic Product (GDP of different countries, but also because of the employment it generates. Since 2009, however, the results of tourism have been severely affected by the economic and financial crisis and it is now essential to analyze the key elements of tourist consumer behavior. In this context, the image that a destination transmits to the market becomes one of the elements which influence tourists the most when choosing a tourist destination. The authors therefore aim to identify the main elements that characterize the image of a tourist destination, as well as their implications for the management of tourist destinations.

  16. Exploring Forensic Implications of the Fusion Drive

    Directory of Open Access Journals (Sweden)

    Shruti Gupta

    2014-09-01

    Full Text Available This paper explores the forensic implications of Apple's Fusion Drive. The Fusion Drive is an example of auto-tiered storage. It uses a combination of a flash drive and a magnetic drive. Data is moved between the drives automatically to maximize system performance. This is different from traditional caches because data is moved and not simply copied. The research included understanding the drive structure, populating the drive, and then accessing data in a controlled setting to observe data migration strategies. It was observed that all the data is first written to the flash drive with 4 GB of free space always maintained. If data on the magnetic drive is frequently accessed, it is promoted to the flash drive while demoting other information. Data is moved at a block-level and not a file-level. The Fusion Drive didn't alter the timestamps of files with data migration.

  17. Heat Shock Proteins and their clinical Implications

    Directory of Open Access Journals (Sweden)

    M. M. Pathan

    Full Text Available Knowledge of the physiological role of heat shock proteins is currently limited; however better understanding of their function and thereby the acquisition of the capacity to harness their power might lead to their use as therapeutic agents and revolutionize clinical practice in a number of areas. Future work is needed to translate the experimental data on the capacity of heat shock proteins to induce tumor protection and immunity to infectious agents into the clinical environment. Approach to cancer vaccine is based on the role of HSP in the presentation of antigens. In several infections and especially autoimmune diseases, the implications of immune responses against HSP are still not properly or fully understood. HSP have clinical significance in conditions such as cardiac hypertrophy, vascular wall injury, cardiac surgery, ischemic preconditioning and ageing. [Veterinary World 2010; 3(12.000: 558-560

  18. Clinical implications of hedgehog signaling pathway inhibitors

    Institute of Scientific and Technical Information of China (English)

    Hailan Liu; Dongsheng Gu; Jingwu Xie

    2011-01-01

    Hedgehog was first described in Drosophila melanogaster by the Nobel laureates Eric Wieschaus and Christiane Nusslein-Volhard. The hedgehog (Hh) pathway is a major regulator of cell differentiation,proliferation, tissue polarity, stem cell maintenance, and carcinogenesis. The first link of Hh signaling to cancer was established through studies of a rare familial disease, Gorlin syndrome, in 1996. Follow-up studies revealed activation of this pathway in basal cell carcinoma, medulloblastoma and, leukemia as well as in gastrointestinal, lung, ovarian, breast, and prostate cancer. Targeted inhibition of Hh signaling is now believed to be effective in the treatment and prevention of human cancer. The discovery and synthesis of specific inhibitors for this pathway are even more exciting. In this review, we summarize major advances in the understanding of Hh signaling pathway activation in human cancer, mouse models for studying Hhmediated carcinogenesis, the roles of Hh signaling in tumor development and metastasis, antagonists for Hh signaling and their clinical implications.

  19. The Risk Implications of Multinational Enterprise

    DEFF Research Database (Denmark)

    Andersen, Torben Juul

    2011-01-01

    Purpose – Multinational structure has been linked to operational flexibilities that can improve corporate adaptability and a knowledge-based view suggests that multinational resource diversity can facilitate responsive opportunities. The enhanced maneuverability from this can reduce earnings...... volatility and hence the corporate performance risk. But, the internationalization process may also require irreversible investments that increase corporate exposures and leave the risk implications of multinational enterprize somewhat ambiguous. Hence, the purpose of the paper is to present an empirical...... debate about the risk effects of a multinational corporate structure and confirms that a diverse multinational presence is associated with positive risk outcomes. Originality/value – The paper complements a limited number of studies with equivocal results and adopts alternative risk outcome measures...

  20. Legal implications of managed care arrangements.

    Science.gov (United States)

    Knox, W A; Epstein, D M

    1994-09-01

    Prior to the 1980s, managed care was virtually nonexistent as a force in health care. Presently, 64 percent of employees in America are covered by managed care plans, including health maintenance organizations (20 percent) and preferred provider organizations (44 percent). In contrast, only 29 percent of employees were enrolled in managed care plans in 1988 and only 47 percent in 1991. To date, the primary reason for this incredible growth in managed care has been economic-market pressure to reduce health care costs. For the foreseeable future, political pressures are likely to fuel this growth, as managed care is at the center of President Clinton's national health care plan. Although there are numerous legal issues surrounding managed care, this article focuses primarily on antitrust implications when forming managed care entities. In addition, the corporate practice of medicine doctrine, certain tax issues, and the fraud and abuse laws are discussed.

  1. Waste management implications of concentrating slimes

    International Nuclear Information System (INIS)

    The anticipated increase in demand for sand-size tailings from the uranium industry suggests that the fine-grained or 'slime' fraction will require special attention for disposal. The Atomic Energy Control Board (AECB) required information on the behaviour and environmental significance of the fine-grained tailings fraction in disposal facilities. Beak Consultants and Golder Associates were contracted to review the significant characteristics of slimes disposal and prepare a report on the physical and chemical characteristics of fine-grained tailings (Phase 1). This report (Phase 2) presents a summary of disposal and management practices for slimes and outlines potential concerns related to these practices. The report also presents an approach to disposal planning and the implications of available and potential management techniques. Experience with the disposal of uranium slimes is scarce and, therefore, relevant information was borrowed from the other mining sectors to predict the consequences of various disposal scenarios

  2. Racism and cardiovascular disease: implications for nursing.

    Science.gov (United States)

    Jackson, Jennifer; McGibbon, Elizabeth; Waldron, Ingrid

    2013-01-01

    The social determinants of health (SDH) are recognized as a prominent influence on health outcomes across the lifespan. Racism is identified as a key SDH. In this article, the authors describe the concept of racism as an SDH, its impact in discriminatory actions and inactions, and the implications for cardiovascular nurses. Although research in Canada on the links among racism, stress, and cardiovascular disease is limited, there is growing evidence about the stress of racism and its long-term impact on cardiovascular health. The authors discuss how cardiovascular nursing could be enhanced through an understanding of racism-related stress, and race-based differences in cardiovascular care. The authors conclude with strategies for action to address this nursing concern.

  3. The Francis Report--dento-legal implications.

    Science.gov (United States)

    Foster, Martin

    2015-05-01

    This article explores the potential implications of the Francis Report for members of the dental team from a dento-legal perspective. It looks at the broad recommendations in light of the existing ethical environment in which dental registrants work and asks what is new and what the recommendations will actually mean for dental professionals in practical terms. Clinical Relevance: The fundamental recommendations of the Francis Report, namely, that those who provide care should put patients' interests first and be open about outcomes and performance, are not new concepts. A breach of these ethically based expectations may, however, create grounds for legal proceedings, which is clearly a significant point for all members of the dental team. It is therefore important to be aware of what is expected of those providing clinical care.

  4. Interstellar Turbulence II: Implications and Effects

    CERN Document Server

    Scalo, J

    2004-01-01

    Interstellar turbulence has implications for the dispersal and mixing of the elements, cloud chemistry, cosmic ray scattering, and radio wave propagation through the ionized medium. This review discusses the observations and theory of these effects. Metallicity fluctuations are summarized, and the theory of turbulent transport of passive tracers is reviewed. Modeling methods, turbulent concentration of dust grains, and the turbulent washout of radial abundance gradients are discussed. Interstellar chemistry is affected by turbulent transport of various species between environments with different physical properties and by turbulent heating in shocks, vortical dissipation regions, and local regions of enhanced ambipolar diffusion. Cosmic rays are scattered and accelerated in turbulent magnetic waves and shocks, and they generate turbulence on the scale of their gyroradii. Radio wave scintillation is an important diagnostic for small scale turbulence in the ionized medium, giving information about the power spe...

  5. Nursing implications for Hepatic arterial perfusion scintigraphy

    International Nuclear Information System (INIS)

    Nurses working in Nuclear Medicine assist in Hepatic Artery Catheter (HAC) perfusion studies. This scan is not widely performed in Australia, the St George hospital for example performs approximately five per year. The purpose of this article is firstly to review the indications and rationale of HAC patency studies. Secondly, this article will stress the clinical implications for the Nuclear Medicine Nurse during this study. Emphasis will be placed on the importance of patient education during the procedure. A brief overview of hepatic anatomy and the radiopharmaceuticals administered during the scan is discussed. Finally, a step by step protocol is presented to show how the perfusion/ shunt study is performed. Copyright (1999) The Australian and New Zealand Society of Nuclear Medicine Inc

  6. Implications of Orientation in Sheared Cocoa Butter

    Science.gov (United States)

    Guthrie, Sarah E.; Mazzanti, Gianfranco; Marangoni, Alejandro; Idziak, Stefan H. J.

    2004-03-01

    We will present x-ray and mechanical studies of oriented phases of cocoa butter. The structural elements of foods play an important role in determining such things as quality and shelf stability. The specific structure and properties of cocoa butter, however, are complicated due to the ability of the cocoa butter to form crystals in six polymorphic forms. Recent work has shown that the application of shear not only accelerates the transitions to more stable polymorphs, but also causes orientation of the crystallites[1]. The implications of orientation on the structures formed under conditions of shear and cooling will be described using x-ray diffraction and mechanical measurements. 1 G. Mazzanti, S. E. Guthrie, E. B. Sirota et al., Crystal Growth & Design 3 (5), 721 (2003).

  7. Psychoneuroimmune implications of type 2 diabetes: redux.

    Science.gov (United States)

    O'Connor, Jason C; Johnson, Daniel R; Freund, Gregory G

    2009-05-01

    A sizable body of knowledge has arisen demonstrating that type 2 diabetes (T2D) is associated with alterations in the innate immune system. The resulting proinflammatory-leaning imbalance is implicated in the development of secondary disease complications and comorbidities, such as delayed wound healing, accelerated progress of atherosclerosis, and retinopathy, in people who have T2D. New experimental data and the results of recently published health-related quality-of-life surveys indicate that individuals who have T2D experience diminished feelings of happiness, well being, and satisfaction with life. These emotional and psychological consequences of T2D point to altered neuroimmunity as a previously unappreciated complication of T2D. This article discusses recent data detailing the impact of T2D on a person's PNI response. PMID:19389586

  8. Safety implications of self-managed teams

    Energy Technology Data Exchange (ETDEWEB)

    Lardner, R.

    1999-08-01

    This report traces the history of self-management and the reasons for the introduction of self-management. The Health and Safety Executive's approach to management of safety, literature on self-managing teams and safety, and published examples of self-managing teams in the petrochemical industry are discussed. Diagnosing the suitability for self-management, and best practice in implementation are considered, four UK case studies involving the BP Chemicals plant in Baglan Bay, the Shell Exploration and Production Cada Platforms, Industrial Colours Limited, and Amec Process and Energy at Great Yarmouth are given. The research undertaken at BP Oil's Grangemouth refinery on safety implications of self-managed teams is reviewed.

  9. Implications of inherent safe nuclear power system

    International Nuclear Information System (INIS)

    The safety of present day nuclear power reactors and research reactors depends on a combination of design features of passive and active systems, and the alert judgement of their operators. A few inherently safe designs of nuclear reactors for power plants are currently under development. In these designs, the passive systems are emphasized, and the active systems are minimized. Also efforts are made to eliminate the potential for human failures that initiate the series of accidents. If a major system fails in these designs, the core is flooded automatically with coolants that flow by gravity, not by mechanical pumps or electromagnetic actuators. Depending on the choice of the coolants--water, liquid metal and helium gas--there are three principal types of inherently safe reactors. In this paper, these inherently safe reactor designs are reviewed and their implications are discussed. Further, future perspectives of their acceptance by nuclear industries are discussed. (author)

  10. Destination image: Origins, Developments and Implications

    Directory of Open Access Journals (Sweden)

    Sérgio Dominique Ferreira Lopes

    2011-04-01

    Full Text Available Over the last few decades, tourism has become one of the main sectors of the global economy, not only because of its contribution to the Gross Domestic Product (GDP of different countries, but also because of the employment it generates. Since 2009, however, the results of tourism have been severely affected by the economic and financial crisis and it is now essential to analyze the key elements of tourist consumer behavior. In this context, the image that a destination transmits to the market becomes one of the elements which influence tourists the most when choosing a tourist destination. The authors therefore aim to identify the main elements that characterize the image of a tourist destination, as well as their implications for the management of tourist destinations.

  11. Public health implications of altered puberty timing

    DEFF Research Database (Denmark)

    Golub, M.S.; Collman, G.W.; Foster, P.M.;

    2008-01-01

    with an increased risk for testicular cancer according to several, but not all, epidemiologic studies. Girls and, possibly, boys who exhibit premature adrenarche are at a higher risk for developing features of metabolic syndrome, including obesity, type 2 diabetes, and cardiovascular disease later in adulthood......Changes in puberty timing have implications for the treatment of individual children, for the risk of later adult disease, and for chemical testing and risk assessment for the population. Children with early puberty are at a risk for accelerated skeletal maturation and short adult height, early...... sexual debut, potential sexual abuse, and psychosocial difficulties. Altered puberty timing is also of concern for the development of reproductive tract cancers later in life. For example, an early age of menarche is a risk factor for breast cancer. A low age at male puberty is associated...

  12. Clinical Implications of Sarcopenic Obesity in Cancer.

    Science.gov (United States)

    Carneiro, Isabella P; Mazurak, Vera C; Prado, Carla M

    2016-10-01

    Sarcopenia has been associated with several negative clinical outcomes in cancer. However, the consequences of sarcopenic obesity, a condition of combined sarcopenia and obesity burden, have been less extensively investigated. The aim of this paper was to review the current evidence on the prevalence and clinical implications of sarcopenic obesity in cancer. A total of 14 studies linking sarcopenic obesity to a clinical outcome in cancer were included. There is considerable inconsistency in methods used to evaluate body composition as well as in the criteria used to define sarcopenic obesity, which limits comparison among studies. Therefore, the prevalence of sarcopenic obesity varied substantially: between 1 and 29 % in studies including individuals from all body mass index categories and between 15 and 36 % for those including obese individuals only. Negative clinical outcomes reported to be associated with sarcopenic obesity included higher risk of dose-limiting toxicity, surgical complications, physical disability, and shorter survival. PMID:27541923

  13. PRIMARY NURSING IMPLICATIONS ON NURSING CARE ASSISTANCE

    Directory of Open Access Journals (Sweden)

    Luciana Mahnis Pereira Carmona

    2002-06-01

    Full Text Available The authors present the method “Primary Nursing”, which has as principle the elevation of thenurse’s autonomy, in which he is responsible for the patient 24 hours a day. The also present the function of eachnurse engaged in that process, pointing out the advantages of the method and its implications in the practice. In itsreview, they put results of 07 present works accomplished with the introduction of the “Primary Nursing”. As finalconsiderations, the state that the “Primary Nursing” improves the quality of assistance given by the nurse, and itsperformance will mainly depend on the nurse’s interest, on changing the reference system towards the professionalcompetence.

  14. Implications for incorporating simulation in nursing education.

    Science.gov (United States)

    Miller, Shelley

    2010-01-01

    The current intricately complex state of health care holds a multitude of challenges for the novice nurse in acquiring, developing, and maintaining standards of proficiency in clinical practice. This paper will explore the implications or reasons for incorporating simulation in nursing education for two primary reasons. First, simulation is an interactive teaching strategy designed for augmenting the learning process. Simulation is an example of active learning that engages the student to think through a situation then take action through the application of knowledge, and finally to self-reflect during the process of debriefing. Secondly, an increasing number of educational institutions have made the commitment to incorporate simulation technology into nursing curricula. PMID:21175101

  15. Public Trust Doctrine Implications of Electricity Production

    DEFF Research Database (Denmark)

    Noel, Lance Douglas; Firestone, Jeremy

    2015-01-01

    ’s impact on those two areas and the comparatively smaller impacts of renewable energy, electricity production has garnered very little public trust doctrine attention. This Article examines how electricity production implicates the public trust doctrine, primarily through the lens of four states...... development; (2) as a legal defense for states to validate actions encouraging renewable electricity development; (3) as a means for courts to more closely scrutinize electricity decisions made by the state; and (4) as an opportunity for state agencies to supplement and guide imperfect statutes. Together......, these four purposes of the public trust can ensure reasonable and timely development of renewable electricity as well as sufficient protection of trust resources....

  16. Rumen bypass nutrients: Manipulation and implications

    International Nuclear Information System (INIS)

    The feeds available for ruminants in developing countries are either agro-industrial by-products or specially grown forage crops. Many of these feeds are low in protein and require supplementation with non-protein N (NPN) to maintain efficient rumen function and digestibility. The principles for utilizing high energy, low protein feeds by ruminants are discussed in relation to the supply of NPN, the establishment of efficient rumen function, maximizing feed intake by means of supplements, and increasing total energy and protein intake by using supplements which bypass the rumen. To illustrate it the application of these principles to feeding systems based on molasses, chopped whole sugar cane and derinded sugar cane is discussed. The implications of the principles in increasing the feeding value of straw are also discussed. (author)

  17. Implications of LHCb measurements and future prospects

    CERN Document Server

    Aaij, R; Adametz, A; Adeva, B; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Anelli, M; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Bachmann, S; Back, J J; Baesso, C; Baldini, W; Band, H; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bates, A; Bauer, Th; Bay, A; Beddow, J; Bediaga, I; Beigbeder-Beau, C; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Benayoun, M; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernard, F; Bernet, R; Bettler, M -O; van Beuzekom, M; van Beveren, V; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blanks, C; Blouw, J; Blusk, S; Bobrov, A; Bocci, V; Bochin, B; Boer Rookhuizen, H; Bogdanova, G; Bonaccorsi, E; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Brarda, L; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Büchler-Germann, A; Burducea, I; Bursche, A; Buytaert, J; Cacérès, T; Cachemiche, J -P; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casajus Ramo, A; Casse, G; Cattaneo, M; Cauet, Ch; Ceelie, L; Chadaj, B; Chanal, H; Charles, M; Charlet, D; Charpentier, Ph; Chebbi, M; Chen, P; Chiapolini, N; Chrzaszcz, M; Ciambrone, P; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Corajod, B; Corti, G; Couturier, B; Cowan, G A; Craik, D; Cunliffe, S; Currie, R; D'Ambrosio, C; D'Antone, I; David, P; David, P N Y; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Groen, P; De Miranda, J M; De Paula, L; De Simone, P; Decamp, D; Deckenhoff, M; Decreuse, G; Degaudenzi, H; Del Buono, L; Deplano, C; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dickens, J; Dijkstra, H; Diniz Batista, P; Dogaru, M; Domingo Bonal, F; Domke, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Drancourt, C; Duarte, O; Dumps, R; Dupertuis, F; Duval, P -Y; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Elsby, D; Evangelisti, F; Falabella, A; Färber, C; Fardell, G; Farinelli, C; Farry, S; Faulkner, P J W; Fave, V; Felici, G; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fitzpatrick, C; Föhr, C; Fontana, M; Fontanelli, F; Forty, R; Fournier, C; Francisco, O; Frank, M; Frei, C; Frei, R; Frosini, M; Fuchs, H; Furcas, S; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gascon, D; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Gets, S; Ghez, Ph; Giachero, A; Gibson, V; Gligorov, V V; Göbel, C; Golovtsov, V; Golubkov, D; Golutvin, A; Gomes, A; Gong, G; Gong, H; Gordon, H; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Gromov, V; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Guzik, Z; Gys, T; Hachon, F; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Harrison, P F; Hartmann, T; He, J; van der Heijden, B; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hicks, E; Hill, D; Hoballah, M; Hofmann, W; Hombach, C; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Ilten, P; Imong, J; Jacobsson, R; Jaeger, A; Jamet, O; Jans, E; Jansen, F; Jansen, L; Jansweijer, P; Jaton, P; Jing, F; John, M; Johnson, D; Jones, C R; Jost, B; Kaballo, M; Kandybei, S; Karacson, M; Karavichev, O; Karbach, T M; Kashchuk, A; Kechadi, T; Kenyon, I R; Kerzel, U; Ketel, T; Keune, A; Khanji, B; Kihm, T; Kluit, R; Kochebina, O; Komarov, V; Koopman, R F; Koppenburg, P; Korolev, M; Kos, J; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Kristic, R; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudenko, Y; Kudryavtsev, V; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Landi, L; Lanfranchi, G; Langenbruch, C; Laptev, S; Latham, T; Lax, I; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leroy, O; Lesiak, T; Li, Y; Li Gioi, L; Likhoded, A; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; von Loeben, J; Lopes, J H; Lopez Asamar, E; Lopez-March, N; Lu, H; Luisier, J; Luo, H; Mac Raighne, A; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Maino, M; Malde, S; Manca, G; Mancinelli, G; Mangiafave, N; Marconi, U; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Matveev, M; Maurice, E; Mauricio, J; Mazurov, A; McCarthy, J; McNulty, R; Meadows, B; Meissner, M; Mejia, H; Mendez-Munoz, V; Merk, M; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mountain, R; Mous, I; Muheim, F; Mul, F; Müller, K; Munneke, B; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Nawrot, A; Needham, M; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Nikitin, N; Nikodem, T; Nikolaiko, Y; Nisar, S; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Ostankov, A; Otalora Goicochea, J M; van Overbeek, M; Owen, P; Pal, B K; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perego, D L; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pessina, G; Petridis, K; Petrolini, A; van Petten, O; Phan, A; Picatoste Olloqui, E; Piedigrossi, D; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polycarpo, E; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pugatch, M; Pugatch, V; Puig Navarro, A; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Rethore, F; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Rodrigues, E; Rodriguez Perez, P; Roeland, E; Rogers, G J; Roiser, S; Romanovsky, V; Romero Vidal, A; de Roo, K; Rouvinet, J; Roy, L; Rudloff, K; Ruf, T; Ruiz, H; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salzmann, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Saornil Gamarra, S; Sapunov, M; Saputi, A; Sarti, A; Satriano, C; Satta, A; Savidge, T; Savrie, M; Schaack, P; Schiller, M; Schimmel, A; Schindler, H; Schleich, S; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schneider, T; Schopper, A; Schuijlenburg, H; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shao, B; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Sigurdsson, S; Silva Coutinho, R; Skwarnicki, T; Slater, M W; Sluijk, T; Smith, N A; Smith, E; Smith, M; Sobczak, K; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Squerzanti, S; Stagni, F; Stahl, S; Steinkamp, O; Stenyakin, O; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Swientek, S; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teklishyn, M; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; Tikhonov, A; van Tilburg, J; Tisserand, V; Tobin, M; Tocut, V; Tolk, S; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Ullaland, O; Urner, D; Uwer, U; Vagnoni, V; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vink, W; Volkov, S; Volkov, V; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Vouters, G; Waldi, R; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Warda, K; Watson, N K; Webber, A D; Websdale, D; Wenerke, P; Whitehead, M; Wicht, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wishahi, J; Witek, M; Witzeling, W; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, Z; Xue, T; Yang, Z; Young, R; Yuan, X; Yushchenko, O; Zangoli, M; Zappon, F; Zavertyaev, M; Zeng, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhong, L; Zverev, E; Zvyagin, A; Zwart, A; Bharucha, A; Bigi, I I; Bobeth, C; Bobrowski, M; Brod, J; Buras, A J; Davies, C T H; Datta, A; Delaunay, C; Descotes-Genon, S; Ellis, J; Feldmann, T; Fleischer, R; Gedalia, O; Girrbach, J; Guadagnoli, D; Hiller, G; Hochberg, Y; Hurth, T; Isidori, G; Jager, S; Jung, M; Kagan, A; Kamenik, J F; Lenz, A; Ligeti, Z; London, D; Mahmoudi, F; Matias, J; Nandi, S; Nir, Y; Paradisi, P; Perez, G; Petrov, A A; Rattazzi, R; Sharpe, S R; Silvestrini, L; Soni, A; Straub, D M; van Dyk, D; Virto, J; Wang, Y M; Weiler, A; Zupan, J

    2013-01-01

    During 2011 the LHCb experiment at CERN collected $1.0 {\\mbox{fb}^{-1}}$ of $\\sqrt{s} = 7 {\\mathrm{\\,Te\\kern -0.1em V}}$ $pp$ collisions. Due to the large heavy quark production cross-sections, these data provide unprecedented samples of heavy flavoured hadrons. The first results from LHCb have made a significant impact on the flavour physics landscape and have definitively proved the concept of a dedicated experiment in the forward region at a hadron collider. This document discusses the implications of these first measurements on classes of extensions to the Standard Model, bearing in mind the interplay with the results of searches for on-shell production of new particles at ATLAS and CMS. The physics potential of an upgrade to the LHCb detector, which would allow an order of magnitude more data to be collected, is emphasised.

  18. IRON-TOLERANT CYANOBACTERIA: IMPLICATIONS FOR ASTROBIOLOGY

    Science.gov (United States)

    Brown, Igor I.; Allen, Carlton C.; Mummey, Daniel L.; Sarkisova, Svetlana A.; McKay, David S.

    2006-01-01

    The review is dedicated to the new group of extremophiles - iron tolerant cyanobacteria. The authors have analyzed earlier published articles about the ecology of iron tolerant cyanobacteria and their diversity. It was concluded that contemporary iron depositing hot springs might be considered as relative analogs of Precambrian environment. The authors have concluded that the diversity of iron-tolerant cyanobacteria is understudied. The authors also analyzed published data about the physiological peculiarities of iron tolerant cyanobacteria. They made the conclusion that iron tolerant cyanobacteria may oxidize reduced iron through the photosystem of cyanobacteria. The involvement of both Reaction Centers 1 and 2 is also discussed. The conclusion that iron tolerant protocyanobacteria could be involved in banded iron formations generation is also proposed. The possible mechanism of the transition from an oxygenic photosynthesis to an oxygenic one is also discussed. In the final part of the review the authors consider the possible implications of iron tolerant cyanobacteria for astrobiology.

  19. Pituitary stem cells: candidates and implications.

    Science.gov (United States)

    Nassiri, Farshad; Cusimano, Michael; Zuccato, Jeff A; Mohammed, Safraz; Rotondo, Fabio; Horvath, Eva; Syro, Luis V; Kovacs, Kalman; Lloyd, Ricardo V

    2013-09-01

    The pituitary is the master endocrine gland of the body. It undergoes many changes after birth, and these changes may be mediated by the differentiation of pituitary stem cells. Stem cells in any tissue source must display (1) pluripotent capacity, (2) capacity for indefinite self-renewal, and (3) a lack of specialization. Unlike neural stem cells identified in the hippocampus and subventricular zone, pituitary stem cells are not associated with one specific cell type. There are many major candidates that are thought to be potential pituitary stem cell sources. This article reviews the evidence for each of the major cell types and discuss the implications of identifying a definitive pituitary stem cell type. PMID:23423660

  20. Income inequality: Implications and relevant economic policies

    Directory of Open Access Journals (Sweden)

    Arestis Philip

    2016-01-01

    Full Text Available The aim of this contribution is to discuss closely the implications of income inequality and the economic policies to tackle it, especially so in view of inequality being one of the main causes of the 2007/2008 international financial crisis and the “great recession” that subsequently emerged. Wealth inequality is also important in this respect, but the focus is on income inequality. Ever since the financial crisis and the subsequent “great recession”, inequality of income, and wealth, has increased and the demand for economic policy initiatives to produce a more equal distribution of income and wealth has become more urgent. Such reduction would help to increase the level of economic activity as has been demonstrated again more recently. A number of economic policy initiatives for this purpose will be the focus of this contribution.

  1. Rehabilitation treatment taxonomy: implications and continuations.

    Science.gov (United States)

    P Dijkers, Marcel; Hart, Tessa; Whyte, John; M Zanca, Jeanne; Packel, Andrew; Tsaousides, Theodore

    2014-01-01

    In relation to the conceptual framework for a rehabilitation treatment taxonomy (RTT), which has been proposed in other articles in this supplement, this article discusses a number of issues relevant to its further development, including creating distinctions within the major target classes; the nature and quantity of allowable targets of treatment; and bracketing as a way of specifying (1) the skill or knowledge taught; (2) the nature of compensation afforded by changes in the environment, assistive technology, and orthotics/prosthetics; and (3) the ingredients in homework a clinician assigns. Clarification is provided regarding the role of the International Classification of Functioning, Disability and Health, focusing a taxonomy on ingredients versus other observable aspects of treatment, and regarding our lack of knowledge and its impact on taxonomy development. Finally, this article discusses the immediate implications of the work to date and presents the need for rehabilitation stakeholders of all disciplines to be involved in further RTT development.

  2. Implications of the Human Genome Project

    Energy Technology Data Exchange (ETDEWEB)

    Kitcher, P.

    1998-11-01

    The Human Genome Project (HGP), launched in 1991, aims to map and sequence the human genome by 2006. During the fifteen-year life of the project, it is projected that $3 billion in federal funds will be allocated to it. The ultimate aims of spending this money are to analyze the structure of human DNA, to identify all human genes, to recognize the functions of those genes, and to prepare for the biology and medicine of the twenty-first century. The following summary examines some of the implications of the program, concentrating on its scientific import and on the ethical and social problems that it raises. Its aim is to expose principles that might be used in applying the information which the HGP will generate. There is no attempt here to translate the principles into detailed proposals for legislation. Arguments and discussion can be found in the full report, but, like this summary, that report does not contain any legislative proposals.

  3. Environmental implications of China's WTO accession

    International Nuclear Information System (INIS)

    China's accession to the WTO in 2001 completed the country's entry into the global economy. We investigate environmental implications of WTO-accession. There are several hypotheses in this area: The scale hypothesis says that production is scaled up and in turn, pollution increases. The composition hypothesis says that composition of industries changes and pollution reflects the new composition. The technique hypothesis says that production methods become cleaner and pollution decreases. We analyze the relative strength of the hypotheses by means of an environmental CGE-model, and in the case of air pollution find support for a composition effect in favor of clean industries. Thanks to the composition effect, emissions to air of greenhouse gases fall. Emissions of particles and SO2 also fall, but emissions of NOx and VOC rise. Since particle and SO2-emissions fall we estimate that public health improves (author)

  4. Wheelchair propulsion biomechanics: implications for wheelchair sports.

    Science.gov (United States)

    Vanlandewijck, Y; Theisen, D; Daly, D

    2001-01-01

    The aim of this article is to provide the reader with a state-of-the-art review on biomechanics in hand rim wheelchair propulsion, with special attention to sport-specific implications. Biomechanical studies in wheelchair sports mainly aim at optimising sport performance or preventing sport injuries. The sports performance optimisation question has been approached from an ergonomic, as well as a skill proficiency perspective. Sports medical issues have been addressed in wheelchair sports mainly because of the extremely high prevalence of repetitive strain injuries such as shoulder impingement and carpal tunnel syndrome. Sports performance as well as sports medical reflections are made throughout the review. Insight in the underlying musculoskeletal mechanisms of hand rim wheelchair propulsion has been achieved through a combination of experimental data collection under realistic conditions, with a more fundamental mathematical modelling approach. Through a synchronised analysis of the movement pattern, force generation pattern and muscular activity pattern, insight has been gained in the hand rim wheelchair propulsion dynamics of people with a disability, varying in level of physical activity and functional potential. The limiting environment of a laboratory, however, has hampered the drawing of sound conclusions. Through mathematical modelling, simulation and optimisation (minimising injury and maximising performance), insight in the underlying musculoskeletal mechanisms during wheelchair propulsion is sought. The surplus value of inverse and forward dynamic simulation of hand rim stroke dynamics is addressed. Implications for hand rim wheelchair sports are discussed. Wheelchair racing, basketball and rugby were chosen because of the significance and differences in sport-specific movement dynamics. Conclusions can easily be transferred to other wheelchair sports where movement dynamics are fundamental. PMID:11347685

  5. Immunoglobulin genes implicated in glioma risk.

    Science.gov (United States)

    Pandey, Janardan P; Kaur, Navtej; Costa, Sandra; Amorim, Julia; Nabico, Rui; Linhares, Paulo; Vaz, Rui; Viana-Pereira, Marta; Reis, Rui M

    2014-01-01

    Both genetic and environmental factors are thought to be causal in gliomagenesis. Several genes have been implicated in glioma development, but the putative role of a major immunity-related gene complex member, immunoglobulin heavy chain γ (IGHG) has not been evaluated. Prior observations that IGHG-encoded γ marker (GM) allotypes exhibit differential sensitivity to an immunoevasion strategy of cytomegalovirus, a pathogen implicated as a promoter of gliomagenesis, has lead us to hypothesize that these determinants are risk factors for glioma. To test this hypothesis, we genotyped the IGHG locus comprising the GM alleles, specifically GM alleles 3 and 17, of 120 glioma patients and 133 controls via TaqMan® genotyping assay. To assess the associations between GM genotypes and the risk of glioma, we applied an unconditional multivariate logistic regression analysis adjusted for potential confounding variables. In comparison to subjects who were homozygous for the GM 17 allele, the GM 3 homozygotes were over twice as likely, and the GM 3/17 heterozygotes were over three times as likely, to develop glioma. Similar results were achieved when analyzed by combining the data corresponding to alleles GM 3 and GM 3/17 in a dominant model. The GM 3/17 genotype and the combination of GM 3 and GM 3/17 were found to be further associated with over 3 times increased risk for high-grade astrocytoma (grades III-IV). Allele frequency analyses also showed an increased risk for gliomas and high-grade astrocytoma in association with GM 3. Our findings support the premise that the GM 3 allele may present risk for the development of glioma, possibly by modulating immunity to cytomegalovirus.

  6. Environmental implications and applications of nanomaterials

    Science.gov (United States)

    Bhattacharya, Priyanka

    Recent advances in material science and nanotechnology have given rise to a myriad of developments, while in the meantime call for research into the impacts of nanomaterials on the environment and human health. Although considerable progress has been made in the past decade concerning the behavior of nanomaterials in biological systems, such understanding is critically lacking with respect to the fate of nanomaterials in ecosystems. Accordingly, this dissertation addresses the interactions between nanomaterials and algae---the major constituent of the aquatic food chain (Part I, Chapter two), and exploits the physicochemistry of nanoscaled synthetic dendritic polymers for environmental applications, especially for water purification that is a focused theme of the entire dossier (Part II, Chapters two--five). This dissertation is organized as follows. Chapter one presents a general review of the physical/physicochemical properties, characterizations, implications---especially ecological implication, and applications of a host of most produced and studied nanomaterials. In addition, advances in environmental applications of nanomaterials are discussed. Chapter two examines algal responses to two major types of engineered nanomaterials---quantum dots and polystyrene. Inhibited photosynthetic activities of green algae are observed as a result of the physical adsorption of the nanomaterials. Chapter three elucidates the physicochemical properties of poly(amidoamine)-tris(hydroxymethyl)amidomethane- and amine-terminated dendrimers towards their applications in water remediation. Here, the capacities and mechanisms of the dendrimers in hosting cationic copper, anionic nitrate, polyaromatic phenanthrene, and the more heterogeneous humic acids are discussed. Based on the results of Chapter three, Chapter four presents a dendrimer-based novel optical scheme for improving the detection sensitivity and selectivity of environmental pollutants. Specifically, the surface plasmon

  7. Alexithymia in eating disorders: therapeutic implications

    Directory of Open Access Journals (Sweden)

    Pinna F

    2014-12-01

    Full Text Available Federica Pinna, Lucia Sanna, Bernardo Carpiniello Department of Public Health, Clinical and Molecular Medicine - Unit of Psychiatry, University of Cagliari, Cagliari, Italy Abstract: A high percentage of individuals affected by eating disorders (ED achieve incomplete recovery following treatment. In an attempt to improve treatment outcome, it is crucial that predictors of outcome are identified, and personalized care approaches established in line with new treatment targets, thus facilitating patient access to evidence-based treatments. Among the psychological factors proposed as predictors of outcome in ED, alexithymia is of outstanding interest. The objective of this paper is to undertake a systematic review of the literature relating to alexithymia, specifically in terms of the implications for treatment of ED. In particular, issues concerning the role of alexithymia as a predictor of outcome and as a factor to be taken into account in the choice of treatment will be addressed. The effect of treatments on alexithymia will also be considered. A search of all relevant literature published in English using PubMed, PsycINFO, and Scopus databases was carried out on the basis of the following keywords: alexithymia, anorexia nervosa, bulimia nervosa, eating disorders, and treatment; no time limits were imposed. Despite the clinical relevance of alexithymia, the number of studies published on the above cited aspects is somewhat limited, and these studies are largely heterogeneous and feature significant methodological weaknesses. Overall, data currently available mostly correlate higher levels of alexithymia with a less favorable outcome in ED. Accordingly, alexithymia is seen as a relevant treatment target with the aim of achieving recovery of these patients. Treatments focusing on improving alexithymic traits, and specifically those targeting emotions, seem to show greater efficacy, although alexithymia levels often remain high even after specific

  8. Alexithymia in eating disorders: therapeutic implications

    Science.gov (United States)

    Pinna, Federica; Sanna, Lucia; Carpiniello, Bernardo

    2015-01-01

    A high percentage of individuals affected by eating disorders (ED) achieve incomplete recovery following treatment. In an attempt to improve treatment outcome, it is crucial that predictors of outcome are identified, and personalized care approaches established in line with new treatment targets, thus facilitating patient access to evidence-based treatments. Among the psychological factors proposed as predictors of outcome in ED, alexithymia is of outstanding interest. The objective of this paper is to undertake a systematic review of the literature relating to alexithymia, specifically in terms of the implications for treatment of ED. In particular, issues concerning the role of alexithymia as a predictor of outcome and as a factor to be taken into account in the choice of treatment will be addressed. The effect of treatments on alexithymia will also be considered. A search of all relevant literature published in English using PubMed, PsycINFO, and Scopus databases was carried out on the basis of the following keywords: alexithymia, anorexia nervosa, bulimia nervosa, eating disorders, and treatment; no time limits were imposed. Despite the clinical relevance of alexithymia, the number of studies published on the above cited aspects is somewhat limited, and these studies are largely heterogeneous and feature significant methodological weaknesses. Overall, data currently available mostly correlate higher levels of alexithymia with a less favorable outcome in ED. Accordingly, alexithymia is seen as a relevant treatment target with the aim of achieving recovery of these patients. Treatments focusing on improving alexithymic traits, and specifically those targeting emotions, seem to show greater efficacy, although alexithymia levels often remain high even after specific treatment. Further investigations are needed to overcome the methodological limitations of previous studies, to understand the actual impact of alexithymia on ED outcome, and to allow more precise

  9. People management implications of virtual workplace arrangements

    Directory of Open Access Journals (Sweden)

    K. Ortlepp

    2006-12-01

    Full Text Available Purpose: The purpose of this paper is to investigate the factors that led to an organisation implementing a particular form of virtual workplace arrangement, namely, home-based work. The benefits and disadvantages associated with this form of work arrangement are explored from both the managers' and home-based employees' perspectives. Design/Methodology/Approach: Given the exploratory nature of the empirical study on which this paper is based, a qualitative research design was adopted so as to ensure that the data collection process was dynamic and probing in nature. Semi-structured in-depth interviews were therefore used as instruments for data collection. Findings: The research findings indicate that virtual work arrangements such as home-based work arrangements have advantages for both employers and employees. For instance, reduction of costs associated with office space and facilities, decrease in absenteeism rates, increased employee job satisfaction and improvements in employees' general quality of life. However, a number of negative experiences related to this form of virtual work arrangement are also evident, for example, feelings of isolation as well as stress related to the inability to have firm boundaries between work and family responsibilities. Implications: Based on the insights gained from the findings in the empirical study, a number of areas that need to be given specific attention when organisations are introducing virtual workplace arrangements of this nature are identified. Recommendations made in this article are important for human resource management specialists as well as core business policy makers considering different forms of organisational design. Originality/Value: Maximising the quality of production and service provided has become the prime objective in most organisations in the 21st century. Technology has made it possible for some jobs to be performed at any place at any time and has facilitated the

  10. Policy implications of technologies for cognitive enhancement

    Energy Technology Data Exchange (ETDEWEB)

    Sarewitz, Daniel R. (Arizona State University, Tempe, AZ); Karas, Thomas H.

    2007-02-01

    The Advanced Concepts Group at Sandia National Laboratory and the Consortium for Science, Policy and Outcomes at Arizona State University convened a workshop in May 2006 to explore the potential policy implications of technologies that might enhance human cognitive abilities. The group's deliberations sought to identify core values and concerns raised by the prospect of cognitive enhancement. The workshop focused on the policy implications of various prospective cognitive enhancements and on the technologies/nanotechnology, biotechnology, information technology, and cognitive science--that enable them. The prospect of rapidly emerging technological capabilities to enhance human cognition makes urgent a daunting array of questions, tensions, ambitions, and concerns. The workshop elicited dilemmas and concerns in ten overlapping areas: science and democracy; equity and justice; freedom and control; intergenerational issues; ethics and competition; individual and community rights; speed and deliberations; ethical uncertainty; humanness; and sociocultural risk. We identified four different perspectives to encompass the diverse issues related to emergence of cognitive enhancement technologies: (1) Laissez-faire--emphasizes freedom of individuals to seek and employ enhancement technologies based on their own judgment; (2) Managed technological optimism--believes that while these technologies promise great benefits, such benefits cannot emerge without an active government role; (3) Managed technological skepticism--views that the quality of life arises more out of society's institutions than its technologies; and (4) Human Essentialism--starts with the notion of a human essence (whether God-given or evolutionary in origin) that should not be modified. While the perspectives differ significantly about both human nature and the role of government, each encompasses a belief in the value of transparency and reliable information that can allow public discussion and

  11. Diagnosis and clinical implications of pancreatobiliary reflux

    Institute of Scientific and Technical Information of China (English)

    Terumi Kamisawa; Hajime Anjiki; Naoto Egawa; Masanao Kurata; Goro Honda; Kouji Tsuruta

    2008-01-01

    The sphincter of Oddi is located at the distal end of the pancreatic and bile ducts and regulates the outflow of bile and pancreatic juice.A common channel can be so long that the junction of the pancreatic and bile ducts is located outside of the duodenal wall,as occurs in pancreaticobiliary maljunction (PBM);in such cases,sphincter action does not functionally affect the junction.As the hydropressure within the pancreatic duct is usually greater than in the bile duct,pancreatic juice frequently refluxes into the biliary duct (pancreatobiliary reflux) in PBM,resulting in carcinogenetic conditions in the biliary tract.Pancreatobiliary reflux can be diagnosed from elevated amylase level in the bile,secretinstimulated dynamic magnetic resonance cholangiop ancreatography,and pancreatography via the minor duodenal papilla.Recently,it has become obvious that pancreatobiliary reflux can occur in individuals without PBM.Pancreatobiliary reflux might be related to biliary carcinogenesis even in some individuals without PBM.Since few systemic studies exist with respect to clinical relevance and implications of the pancreatobiliary reflux in individuals with normal pancreaticobiliary junction,further prospective clinical studies including appropriate management should be performed.

  12. Framework and implications of virtual neurorobotics

    Directory of Open Access Journals (Sweden)

    2008-07-01

    Full Text Available Despite decades of societal investment in artificial learning systems, truly “intelligent” systems have yet to be realized. These traditional models are based on input-output pattern optimization and/or cognitive production rule modeling. One response has been social robotics, using the interaction of human and robot to capture important cognitive dynamics such as cooperation and emotion; to date, these systems still incorporate traditional learning algorithms. More recently, investigators are focusing on the core assumptions of the brain “algorithm” itself—trying to replicate uniquely “neuromorphic” dynamics such as action potential spiking and synaptic learning. Only now are large-scale neuromorphic models becoming feasible, due to the availability of powerful supercomputers and an expanding supply of parameters derived from research into the brain’s interdependent electrophysiological, metabolomic and genomic networks. Personal computer technology has also led to the acceptance of computer-generated humanoid images, or “avatars”, to represent intelligent actors in virtual realities. In a recent paper, we proposed a method of virtual neurorobotics (VNR in which the approaches above (social-emotional robotics, neuromorphic brain architectures, and virtual reality projection are hybridized to rapidly forward-engineer and develop increasingly complex, intrinsically intelligent systems. In this paper, we synthesize our research and related work in the field and provide a framework for VNR, with wider implications for research and practical applications.

  13. Conservation Documentation and the Implications of Digitisation

    Directory of Open Access Journals (Sweden)

    Michelle Moore

    2001-11-01

    Full Text Available Conservation documentation can be defined as the textual and visual records collected during the care and treatment of an object. It can include records of the object's condition, any treatment done to the object, any observations or conclusions made by the conservator as well as details on the object's past and present environment. The form of documentation is not universally agreed upon nor has it always been considered an important aspect of the conservation profession. Good documentation tells the complete story of an object thus far and should provide as much information as possible for the future researcher, curator, or conservator. The conservation profession will benefit from digitising its documentation using software such as databases and hardware like digital cameras and scanners. Digital technology will make conservation documentation more easily accessible, cost/time efficient, and will increase consistency and accuracy of the recorded data, and reduce physical storage space requirements. The major drawback to digitising conservation records is maintaining access to the information for the future; the notorious pace of technological change has serious implications for retrieving data from any machine- readable medium.

  14. Assortative mating for relative weight: genetic implications.

    Science.gov (United States)

    Allison, D B; Neale, M C; Kezis, M I; Alfonso, V C; Heshka, S; Heymsfield, S B

    1996-03-01

    Most work on the genetics of relative weight has not considered the role of assortative mating, i.e., mate selection based on similarity between mates. We investigated the extent to which engaged men and women in an archival longitudinal database were similar to each other in relative body weight prior to marriage and cohabitation. After controlling for age, a small but statistically significant mate correlation was found for relative weight (r=.13, p=.023), indicating some assortative mating. Furthermore, we examined whether mate similarity in relative weight prior to marriage predicts survival of the marriage. No significant effects were found. In sum, these results are consistent with those of other studies in suggesting that there is a small but significant intermate correlation for relative weight. However, they are unique in showing that these results cannot be explained on the basis of (a) cohabitation, (b) age similarity, or (c) selective survival of marriages between couples more similar in relative weight. The implications of these findings for heritability studies, linkage studies, and the estimation of shared environmental effects are discussed. PMID:8639146

  15. Science and religion: implications for science educators

    Science.gov (United States)

    Reiss, Michael J.

    2010-03-01

    A religious perspective on life shapes how and what those with such a perspective learn in science; for some students a religious perspective can hinder learning in science. For such reasons Staver's article is to be welcomed as it proposes a new way of resolving the widely perceived discord between science and religion. Staver notes that Western thinking has traditionally postulated the existence and comprehensibility of a world that is external to and independent of human consciousness. This has led to a conception of truth, truth as correspondence, in which our knowledge corresponds to the facts in this external world. Staver rejects such a conception, preferring the conception of truth as coherence in which the links are between and among independent knowledge claims themselves rather than between a knowledge claim and reality. Staver then proposes constructivism as a vehicle potentially capable of resolving the tension between religion and science. My contention is that the resolution between science and religion that Staver proposes comes at too great a cost—both to science and to religion. Instead I defend a different version of constructivism where humans are seen as capable of generating models of reality that do provide richer and more meaningful understandings of reality, over time and with respect both to science and to religion. I argue that scientific knowledge is a subset of religious knowledge and explore the implications of this for science education in general and when teaching about evolution in particular.

  16. Rehabilitation of executive functions: Implications and strategies

    Directory of Open Access Journals (Sweden)

    Bruno Kluwe-Schiavon

    2013-01-01

    Full Text Available Executive Functions (EF concern a range of abilities including problem-solving, planning, initiation, selfmonitoring,conscious attention, cope with new situations and the ability to modify plans if necessary. It’s a high cognitive function that is crucial for a person to get engaged and maintain daily activities whilst keeping a good quality of life. Problems in the EF were formerly known as Dysexecutive Syndrome (DS. There are many models concerning DS, although the literature on the subject still remains unclear. Several works appoint the effects brought by elderly life, as well as abuse of drugs and some psychopathologies. These factors are known to increase the distress of the frontal circuits and that could be associated to executive deficits. The effects of DS would compromise individuals in day-to-day routine, academic, social and labor fields. There is a growing body of studies trying to determine the causes, implications, associations and the best way to take care of these effects. This work intends to review DS, focusing on the most important fields related to this area, such as psychopathology associations, cognitive reserve, assessment and cognitive rehabilitation programs.

  17. Prostate cancer epigenetics and its clinical implications

    Directory of Open Access Journals (Sweden)

    Srinivasan Yegnasubramanian

    2016-01-01

    Full Text Available Normal cells have a level of epigenetic programming that is superimposed on the genetic code to establish and maintain their cell identity and phenotypes. This epigenetic programming can be thought as the architecture, a sort of cityscape, that is built upon the underlying genetic landscape. The epigenetic programming is encoded by a complex set of chemical marks on DNA, on histone proteins in nucleosomes, and by numerous context-specific DNA, RNA, protein interactions that all regulate the structure, organization, and function of the genome in a given cell. It is becoming increasingly evident that abnormalities in both the genetic landscape and epigenetic cityscape can cooperate to drive carcinogenesis and disease progression. Large-scale cancer genome sequencing studies have revealed that mutations in genes encoding the enzymatic machinery for shaping the epigenetic cityscape are among the most common mutations observed in human cancers, including prostate cancer. Interestingly, although the constellation of genetic mutations in a given cancer can be quite heterogeneous from person to person, there are numerous epigenetic alterations that appear to be highly recurrent, and nearly universal in a given cancer type, including in prostate cancer. The highly recurrent nature of these alterations can be exploited for development of biomarkers for cancer detection and risk stratification and as targets for therapeutic intervention. Here, we explore the basic principles of epigenetic processes in normal cells and prostate cancer cells and discuss the potential clinical implications with regards to prostate cancer biomarker development and therapy.

  18. GIS interoperability: current activities and military implications

    Science.gov (United States)

    Lam, Sylvia

    1997-07-01

    Geographic information systems (GIS) are gaining importance in military operations because of their capability to spatially and visually integrate various kinds of information. In an era of limited resources, geospatial data must be shared efficiently whenever possible. The military-initiated Global Geospatial Information and Services (GGI&S) Project aims at developing the infrastructure for GIS interoperability for the military. Current activities in standardization and new technology have strong implications on the design and development of GGI&S. To facilitate data interoperability at both the national and international levels, standards and specifications in geospatial data sharing are being studied, developed and promoted. Of particular interest to the military community are the activities related to the NATO DIGEST, ISO TC/211 Geomatics standardization and the industry-led Open Geodata Interoperability Specifications (OGIS). Together with new information technology, standardization provides the infrastructure for interoperable GIS for both civilian and military environments. The first part of this paper describes the major activities in standardization. The second part presents the technologies developed at DREV in support of the GGI&S. These include the Open Geospatial Datastore Interface (OGDI) and the geospatial data warehouse. DREV has been working closely with Defence Geomatics and private industry in the research and development of new technology for the GGI&S project.

  19. Big Data: Implications for Health System Pharmacy.

    Science.gov (United States)

    Stokes, Laura B; Rogers, Joseph W; Hertig, John B; Weber, Robert J

    2016-07-01

    Big Data refers to datasets that are so large and complex that traditional methods and hardware for collecting, sharing, and analyzing them are not possible. Big Data that is accurate leads to more confident decision making, improved operational efficiency, and reduced costs. The rapid growth of health care information results in Big Data around health services, treatments, and outcomes, and Big Data can be used to analyze the benefit of health system pharmacy services. The goal of this article is to provide a perspective on how Big Data can be applied to health system pharmacy. It will define Big Data, describe the impact of Big Data on population health, review specific implications of Big Data in health system pharmacy, and describe an approach for pharmacy leaders to effectively use Big Data. A few strategies involved in managing Big Data in health system pharmacy include identifying potential opportunities for Big Data, prioritizing those opportunities, protecting privacy concerns, promoting data transparency, and communicating outcomes. As health care information expands in its content and becomes more integrated, Big Data can enhance the development of patient-centered pharmacy services.

  20. Implications of preoperative hypoalbuminemia in colorectal surgery.

    Science.gov (United States)

    Truong, Adam; Hanna, Mark H; Moghadamyeghaneh, Zhobin; Stamos, Michael J

    2016-05-27

    Serum albumin has traditionally been used as a quantitative measure of a patient's nutritional status because of its availability and low cost. While malnutrition has a clear definition within both the American and European Societies for Parenteral and Enteral Nutrition clinical guidelines, individual surgeons often determine nutritional status anecdotally. Preoperative albumin level has been shown to be the best predictor of mortality after colorectal cancer surgery. Specifically in colorectal surgical patients, hypoalbuminemia significantly increases the length of hospital stay, rates of surgical site infections, enterocutaneous fistula risk, and deep vein thrombosis formation. The delay of surgical procedures to allow for preoperative correction of albumin levels in hypoalbuminemic patients has been shown to improve the morbidity and mortality in patients with severe nutritional risk. The importance of preoperative albumin levels and the patient's chronic inflammatory state on the postoperative morbidity and mortality has led to the development of a variety of surgical scoring systems to predict outcomes efficiently. This review attempts to provide a systematic overview of albumin and its role and implications in colorectal surgery. PMID:27231513

  1. Karyomorphology of Taiwanese Begonia (Begoniaceae): taxonomic implications.

    Science.gov (United States)

    Oginuma, Kazuo; Peng, Ching-I

    2002-06-01

    The karyomorphology of all 14 species of Taiwanese Begonia was investigated to elucidate their chromosome features and chromosomal evolution. Among all species investigated, differences in chromosome features are found in: (1) chromosome number 2 n = 22, 26, 36, 38, 52, 60, 64, 82, and (2) frequencies of chromosomes with secondary, tertiary, and/or small constrictions of polyploids, ranging from 23% to 63%, which is higher than the expected value of about 9%. It is suggested that after polyploidization from the diploid species (i.e., 2 n = 22 and frequencies of chromosomes with secondary, tertiary, and/or small constrictions of polyploids of about 9%), chromosome translocations occurred, followed by a decrease in chromosome number, and subsequently stabilized genomes were formed in various species in Taiwan. The karyomorphological evidence also suggested that the chromosome morphology has evolved in parallel in the begonias belonging to different sections in Taiwan. The variation in chromosomal features is more complex than the variation in floral and fruit morphologies. Karyomorphological data also supports the recognition of five new species in Taiwan: Begonia bouffordii, B. chuyunshanensis, B. pinglinensis, B. tengchiana, and B. wutaiana. Based on detailed karyomorphological analyses, the taxonomic implications, speciation, and chromosomal evolution in Taiwanese Begoniaare discussed.

  2. Neurobiology and clinical implications of lucid dreaming.

    Science.gov (United States)

    Mota-Rolim, Sérgio A; Araujo, John F

    2013-11-01

    Several lines of evidence converge to the idea that rapid eye movement sleep (REMS) is a good model to foster our understanding of psychosis. Both REMS and psychosis course with internally generated perceptions and lack of rational judgment, which is attributed to a hyperlimbic activity along with hypofrontality. Interestingly, some individuals can become aware of dreaming during REMS, a particular experience known as lucid dreaming (LD), whose neurobiological basis is still controversial. Since the frontal lobe plays a role in self-consciousness, working memory and attention, here we hypothesize that LD is associated with increased frontal activity during REMS. A possible way to test this hypothesis is to check whether transcranial magnetic or electric stimulation of the frontal region during REMS triggers LD. We further suggest that psychosis and LD are opposite phenomena: LD as a physiological awakening while dreaming due to frontal activity, and psychosis as a pathological intrusion of dream features during wake state due to hypofrontality. We further suggest that LD research may have three main clinical implications. First, LD could be important to the study of consciousness, including its pathologies and other altered states. Second, LD could be used as a therapy for recurrent nightmares, a common symptom of depression and post-traumatic stress disorder. Finally, LD may allow for motor imagery during dreaming with possible improvement of physical rehabilitation. In all, we believe that LD research may clarify multiple aspects of brain functioning in its physiological, altered and pathological states.

  3. Physiological Implications of Myocardial Scar Structure.

    Science.gov (United States)

    Richardson, William J; Clarke, Samantha A; Quinn, T Alexander; Holmes, Jeffrey W

    2015-10-01

    Once myocardium dies during a heart attack, it is replaced by scar tissue over the course of several weeks. The size, location, composition, structure, and mechanical properties of the healing scar are all critical determinants of the fate of patients who survive the initial infarction. While the central importance of scar structure in determining pump function and remodeling has long been recognized, it has proven remarkably difficult to design therapies that improve heart function or limit remodeling by modifying scar structure. Many exciting new therapies are under development, but predicting their long-term effects requires a detailed understanding of how infarct scar forms, how its properties impact left ventricular function and remodeling, and how changes in scar structure and properties feed back to affect not only heart mechanics but also electrical conduction, reflex hemodynamic compensations, and the ongoing process of scar formation itself. In this article, we outline the scar formation process following a myocardial infarction, discuss interpretation of standard measures of heart function in the setting of a healing infarct, then present implications of infarct scar geometry and structure for both mechanical and electrical function of the heart and summarize experiences to date with therapeutic interventions that aim to modify scar geometry and structure. One important conclusion that emerges from the studies reviewed here is that computational modeling is an essential tool for integrating the wealth of information required to understand this complex system and predict the impact of novel therapies on scar healing, heart function, and remodeling following myocardial infarction. PMID:26426470

  4. China's Import of Wastes and Its Implications

    Institute of Scientific and Technical Information of China (English)

    Guo Dongmei

    2008-01-01

    The trade of wastes in the world has been increasing and China has become the largest importer of wastes. This paper examines the import trend of different wastes and finds out that the total import volume to China approved by the Chinese government keeps increasing and the illegal trade can not be banned despite repeated prohibitions; therefore, China is not only "a world factory", but actually "a global garbage dump". In order to well understand the implications of wastes import, this paper further analyzes the resource and environmental effects and risks of different wastes imports as well as the strong driving force of wastes imports. Based on these detailed analysis and solid data, policy recommendations are put forward to reduce the demand for raw materials, to further strengthen the inspection of and supervision over the international trade of the wastes that can be used as raw materials by using the life cycle analysis and risk analysis, to improve the environmental standards and strengthen the disposal capacity, to re-export the raw materials produced from the imported wastes, to develop the long-term planning for the import of wastes and to promote international cooperation.

  5. Biological behaviour and clinical implications of micrometastases.

    LENUS (Irish Health Repository)

    Kell, M R

    2012-02-03

    BACKGROUND: The most important prognostic determinant in cancer is the identification of disseminated tumour burden (metastases). Micrometastases are microscopic (smaller than 2 mm) deposits of malignant cells that are segregated spatially from the primary tumour and depend on neovascular formation (angiogenesis) to propagate. METHODS: The electronic literature (1966 to present) on micrometastases and their implications in malignant melanoma and epithelial cancers was reviewed. RESULTS: Immunohistochemical techniques combined with serial sectioning offer the best accuracy for detection of nodal micrometastases. Molecular techniques should be reserved for blood samples or bone marrow aspirates. Detection of micrometastases in regional lymph nodes and\\/or bone marrow confers a poor prognosis in epithelial cancers. The concept of sentinel node biopsy combined with serial sectioning and dedicated screening for micrometastases may improve staging procedures. Strategies against angiogenesis may provide novel therapies to induce and maintain micrometastatic dormancy. CONCLUSION: The concept of micrometastases has resulted in a paradigm shift in the staging of epithelial tumours and our overall understanding of malignant processes.

  6. Prostate cancer epigenetics and its clinical implications.

    Science.gov (United States)

    Yegnasubramanian, Srinivasan

    2016-01-01

    Normal cells have a level of epigenetic programming that is superimposed on the genetic code to establish and maintain their cell identity and phenotypes. This epigenetic programming can be thought as the architecture, a sort of cityscape, that is built upon the underlying genetic landscape. The epigenetic programming is encoded by a complex set of chemical marks on DNA, on histone proteins in nucleosomes, and by numerous context-specific DNA, RNA, protein interactions that all regulate the structure, organization, and function of the genome in a given cell. It is becoming increasingly evident that abnormalities in both the genetic landscape and epigenetic cityscape can cooperate to drive carcinogenesis and disease progression. Large-scale cancer genome sequencing studies have revealed that mutations in genes encoding the enzymatic machinery for shaping the epigenetic cityscape are among the most common mutations observed in human cancers, including prostate cancer. Interestingly, although the constellation of genetic mutations in a given cancer can be quite heterogeneous from person to person, there are numerous epigenetic alterations that appear to be highly recurrent, and nearly universal in a given cancer type, including in prostate cancer. The highly recurrent nature of these alterations can be exploited for development of biomarkers for cancer detection and risk stratification and as targets for therapeutic intervention. Here, we explore the basic principles of epigenetic processes in normal cells and prostate cancer cells and discuss the potential clinical implications with regards to prostate cancer biomarker development and therapy. PMID:27212125

  7. On the normative implications of social neuroscience

    Directory of Open Access Journals (Sweden)

    Arleen Salles

    2013-04-01

    Full Text Available Within the last decades, brain science has been offering new insights into the relationship among diverse psychological processes and the neural correlates of our moral thought and behavior. Despite the distinction between the explanatory/descriptive nature of science and the normative nature of morality, some neuroethicists have claimed that neuroscientific findings have normative implications. In this paper, I identify three interpretations of the claim. The first focuses on neuroscience’s role in explaining the origin of morality and of moral values and how neurobiology is the bases of moral behavior. A second version is about the role that neuroscientific knowledge can play in showing the psychological plausibility of the moral psychology underlying some ethical approaches. Finally, a third version advances that neuroscience could play a role in determining the moral plausibility of some normative approaches. My aim is to delineate each version and highlight the issues raised to suggest that while neuroscience might provide information regarding the nature of moral reasoning, its role in the normative discussion itself is still quite limited.

  8. Superoxide Ion: Generation and Chemical Implications.

    Science.gov (United States)

    Hayyan, Maan; Hashim, Mohd Ali; AlNashef, Inas M

    2016-03-01

    Superoxide ion (O2(•-)) is of great significance as a radical species implicated in diverse chemical and biological systems. However, the chemistry knowledge of O2(•-) is rather scarce. In addition, numerous studies on O2(•-) were conducted within the latter half of the 20th century. Therefore, the current advancement in technology and instrumentation will certainly provide better insights into mechanisms and products of O2(•-) reactions and thus will result in new findings. This review emphasizes the state-of-the-art research on O2(•-) so as to enable researchers to venture into future research. It comprises the main characteristics of O2(•-) followed by generation methods. The reaction types of O2(•-) are reviewed, and its potential applications including the destruction of hazardous chemicals, synthesis of organic compounds, and many other applications are highlighted. The O2(•-) environmental chemistry is also discussed. The detection methods of O2(•-) are categorized and elaborated. Special attention is given to the feasibility of using ionic liquids as media for O2(•-), addressing the latest progress of generation and applications. The effect of electrodes on the O2(•-) electrochemical generation is reviewed. Finally, some remarks and future perspectives are concluded. PMID:26875845

  9. NUTRITIONAL AND HEALTH IMPLICATIONS OF LEGUMES

    Directory of Open Access Journals (Sweden)

    Mebrahtom Gebrelibanos*, Dinka Tesfaye, Y. Raghavendra and Biruk Sintayeyu

    2013-04-01

    Full Text Available ABSTRACT: Legumes are plants in the family Fabaceae characterized by seeds in pods that are often edible though sometimes poisonous. The nutrient content (protein, carbohydrate and micronutrients of legumes contribute to address under-nutrition, especially protein-calorie malnutrition among children and nursing mothers in developing countries where supplementing cereal-based diets with legumes is suggested as one of the best solutions to protein calorie malnutrition. Anti-nutritional factors, in legumes, may limit their biological value and acceptance as a regular food item, yet they are readily removable and recent research has shown potential health benefits of some of these compounds; and hence, manipulation of processing conditions may be required to remove or reduce only those unwanted components. Moreover, legumes play a role in prevention, improvement and/or treatment of disease conditions such as, diabetes mellitus, cardiovascular diseases, cancer diseases (e.g breast and prostate cancers and lowers blood cholesterol level. Most of these disease conditions are associated with over-nutrition and obesity and are considered as diseases of the rich. It is, therefore, claimed that including legumes in a health-promoting diet is important in meeting the major dietary recommendations to improve the nutritional status of undernourished as well as over-nourished individuals, and to reduce risk of chronic diseases such as cardiovascular disease, diabetes mellitus and cancer. In this review, some of the scientific viewpoints that attempt to justify the nutritional contributions, anti-nutritional considerations and health implications of legumes are discussed.

  10. Implications and Prospects of the GNEP

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Jae-Soo; Lee, Byung-Wook; Lee, Han-Myung; Ko, Han-Suk; Lee, Kwang-Seok; Kim, Hak-Ro [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2008-05-15

    As increased recognition for a role of an economical carbon-free nuclear energy, it is expected that possibility for introduction and an expansion of nuclear power plants (NPPs) will be increased around the world,1) with pursuing self-reliant nuclear fuel cycle in certain states to secure assurances of nuclear fuel supply. However, the pursuit of sensitive nuclear technology such as enrichment and reprocessing has led to concerns about nuclear proliferation. The disclosure of nuclear black market has threatened the current global nonproliferation regime.2) To respond to these concerns, efforts have been made to overcome the loophole of the existing nuclear nonproliferation regime. In February 2004, US President Bush proposed that nuclear exporters refuse to transfer sensitive nuclear technology to prevent new states from producing fissile material to close a loophole in the NPT.3) Meanwhile as the amount of spent nuclear fuel (SNF) by once-through fuel cycle increases, the US needs multiple repositories by the end of the century.4) In February 2006, therefore, Bush administration announced the Global Nuclear Energy Partnership (GNEP), which can bring about expansion of nuclear energy including SNF management while decreasing the risk of nuclear proliferation. It is expected that the GNEP will have an effect on national nuclear programs of participating countries as well as nuclear international cooperation. In this regard, this paper discusses the implication of the GNEP and its prospects.

  11. Comprehensive Map of Molecules Implicated in Obesity.

    Science.gov (United States)

    Jagannadham, Jaisri; Jaiswal, Hitesh Kumar; Agrawal, Stuti; Rawal, Kamal

    2016-01-01

    Obesity is a global epidemic affecting over 1.5 billion people and is one of the risk factors for several diseases such as type 2 diabetes mellitus and hypertension. We have constructed a comprehensive map of the molecules reported to be implicated in obesity. A deep curation strategy was complemented by a novel semi-automated text mining system in order to screen 1,000 full-length research articles and over 90,000 abstracts that are relevant to obesity. We obtain a scale free network of 804 nodes and 971 edges, composed of 510 proteins, 115 genes, 62 complexes, 23 RNA molecules, 83 simple molecules, 3 phenotype and 3 drugs in "bow-tie" architecture. We classify this network into 5 modules and identify new links between the recently discovered fat mass and obesity associated FTO gene with well studied examples such as insulin and leptin. We further built an automated docking pipeline to dock orlistat as well as other drugs against the 24,000 proteins in the human structural proteome to explain the therapeutics and side effects at a network level. Based upon our experiments, we propose that therapeutic effect comes through the binding of one drug with several molecules in target network, and the binding propensity is both statistically significant and different in comparison with any other part of human structural proteome. PMID:26886906

  12. Medical implications of elder abuse and neglect.

    Science.gov (United States)

    Dong, XinQi

    2005-05-01

    Recognition of elder abuse and neglect among health care professionals has been a relatively recent phenomenon. Each year, millions of elderly persons suffer as the result of abuse and neglect. Their quality of life is severely jeopardized in the form of worsened functional status and progressive dependency, poorly rated self-health, feelings of helplessness, and from the vicious cycle of social isolation, stress and further psychologic decline. Other medical implications of abuse and neglect include higher health systems use in the form of frequent ER visits, higher hospitalization, and higher nursing home placement; most importantly, it is an independent predictor for higher mortality. Physicians are well situated in detecting and reporting suspected cases and taking care of the frail elders who are victims of abuse and neglect, but there are barriers on the individual level, and there is a broader need for system change. Through education, training, and reinforcement, there are strategies to get health care professionals more involved and provide effective management protocols and guidelines for us to advocate for our patients in the current epidemic of elder abuse and neglect. PMID:15804552

  13. Mechanisms of bilirubin toxicity: clinical implications.

    Science.gov (United States)

    Hansen, Thor Willy Ruud

    2002-12-01

    The basic mechanism of kernicterus and bilirubin encephalopathy has not been unequivocally determined. Much knowledge has been gained about phenomena that contribute to bilirubin neurotoxicity, and this knowledge has implications for clinical practice. Conditions that impact on blood-brain barrier function, increase brain blood flow, or impact on bilirubin metabolism, including its transport in serum, should be avoided, if possible. Such conditions include drugs and drug stabilizers that compete with bilirubin binding to albumin, or that inhibit P-glycoprotein in the blood-brain barrier, prematurity/immaturity, and clinically significant illness in the infant that involves hemolysis, respiratory and metabolic acidosis, infection, asphyxia, hypoxia and (perhaps) hyperoxia, and hyperosmolality. If these conditions are not avoidable then there should be a more aggressive approach to the treatment of hyperbilirubinemia. The limits of tolerance for hyperbilirubinemia varies among neonates and there are no tools to determine with certainty when a particular infant is approaching the danger zone. Neurological symptoms in a jaundiced infant require extreme vigilance, and, in most cases, immediate intervention. PMID:12516745

  14. Environmental implications of increased biomass energy use

    Energy Technology Data Exchange (ETDEWEB)

    Miles, T.R. Sr.; Miles, T.R. Jr. (Miles (Thomas R.), Portland, OR (United States))

    1992-03-01

    This study reviews the environmental implications of continued and increased use of biomass for energy to determine what concerns have been and need to be addressed and to establish some guidelines for developing future resources and technologies. Although renewable biomass energy is perceived as environmentally desirable compared with fossil fuels, the environmental impact of increased biomass use needs to be identified and recognized. Industries and utilities evaluating the potential to convert biomass to heat, electricity, and transportation fuels must consider whether the resource is reliable and abundant, and whether biomass production and conversion is environmentally preferred. A broad range of studies and events in the United States were reviewed to assess the inventory of forest, agricultural, and urban biomass fuels; characterize biomass fuel types, their occurrence, and their suitability; describe regulatory and environmental effects on the availability and use of biomass for energy; and identify areas for further study. The following sections address resource, environmental, and policy needs. Several specific actions are recommended for utilities, nonutility power generators, and public agencies.

  15. Epigenetics and its implications for ecotoxicology.

    Science.gov (United States)

    Vandegehuchte, Michiel B; Janssen, Colin R

    2011-05-01

    Epigenetics is the study of mitotically or meiotically heritable changes in gene function that occur without a change in the DNA sequence. Interestingly, epigenetic changes can be triggered by environmental factors. Environmental exposure to e.g. metals, persistent organic pollutants or endocrine disrupting chemicals has been shown to modulate epigenetic marks, not only in mammalian cells or rodents, but also in environmentally relevant species such as fish or water fleas. The associated changes in gene expression often lead to modifications in the affected organism's phenotype. Epigenetic changes can in some cases be transferred to subsequent generations, even when these generations are no longer exposed to the external factor which induced the epigenetic change, as observed in a study with fungicide exposed rats. The possibility of this phenomenon in other species was demonstrated in water fleas exposed to the epigenetic drug 5-azacytidine. This way, populations can experience the effects of their ancestors' exposure to chemicals, which has implications for environmental risk assessment. More basic research is needed to assess the potential phenotypic and population-level effects of epigenetic modifications in different species and to evaluate the persistence of chemical exposure-induced epigenetic effects in multiple subsequent generations.

  16. [Hepatitis E virus: Blood transfusion implications].

    Science.gov (United States)

    Gallian, P; Piquet, Y; Assal, A; Djoudi, R; Chiaroni, J; Izopet, J; Tiberghien, P

    2014-11-01

    Hepatitis E virus (HEV) is a non-enveloped RNA virus transmitted by the fecal-oral route. Autochthonous hepatitis E occurring in developed countries is caused by genotypes 3 and 4 and is a zoonotic infection. Humans are infected mostly after ingestion of undercooked meat from infected animals. Most HEV 3 and 4 infections are clinically inapparent. However, genotype 3 (HEV 3) can lead to chronic hepatitis in immuno-compromised patients such as organ-transplant recipients and patients with haematological malignancies. In Europe, HEV 3 is implicated in transfusion-transmitted HEV infection. In France, as observed in several European countries, prevalence of HEV RNA and specific IgG antibodies are high indicating that viral circulation is important. The systematic HEV NAT screening of blood donations used for preparation of solvent detergent plasma indicate that 1 to 2218 donation is infected by HEV RNA. The need or implementation's impacts of safety measures to prevent HEV transmission by blood transfusion are under reflexion by French's health authorities. The HEV NAT screening is the only available tool of prevention. Alternative strategies are under investigation including individual or mini pool NAT testing all or part of blood donations. PMID:25267201

  17. Big Data: Implications for Health System Pharmacy.

    Science.gov (United States)

    Stokes, Laura B; Rogers, Joseph W; Hertig, John B; Weber, Robert J

    2016-07-01

    Big Data refers to datasets that are so large and complex that traditional methods and hardware for collecting, sharing, and analyzing them are not possible. Big Data that is accurate leads to more confident decision making, improved operational efficiency, and reduced costs. The rapid growth of health care information results in Big Data around health services, treatments, and outcomes, and Big Data can be used to analyze the benefit of health system pharmacy services. The goal of this article is to provide a perspective on how Big Data can be applied to health system pharmacy. It will define Big Data, describe the impact of Big Data on population health, review specific implications of Big Data in health system pharmacy, and describe an approach for pharmacy leaders to effectively use Big Data. A few strategies involved in managing Big Data in health system pharmacy include identifying potential opportunities for Big Data, prioritizing those opportunities, protecting privacy concerns, promoting data transparency, and communicating outcomes. As health care information expands in its content and becomes more integrated, Big Data can enhance the development of patient-centered pharmacy services. PMID:27559194

  18. Microsporogenesis of Cycas and its systematic implications

    Institute of Scientific and Technical Information of China (English)

    Hua-Fen ZHANG; Hai-Bo OUYANG; Jin-Yan DU; Shou-Zhou ZHANG; Yong LI; Hong WU

    2012-01-01

    Taxonomists are divided over the infrageneric classification and species delimitation within the genus Cycas.The division is largely determined by whether a broad or narrow species concept is adopted,the latter approach being based on apparently minor morphological differences.It is well known that cytokinesis in the cells of pollen provides important evidence for plant taxonomy,particularly at the higher taxonomic level.Here we present the first broad comparison of the cytokinesis of male meiosis in five species of Cycas.A comparative analysis of microsporogenesis in Cycas was carried out using conventional microscopy,semi-thin sectioning,histochemistry,and fluorescence microscopy with a focus on the cytokinesis of meiosis in the pollen of dividing cells.Our observations confirmed that,contrary to previous reports,the cytokinesis in male meiosis of five species in Cycas is simultaneous at the end of second meiosis.The basic model of microsporogenesis and its systematic implications in Cycas is discussed based both on previous reports and our new results.

  19. The coevolutionary implications of host tolerance.

    Science.gov (United States)

    Best, Alex; White, Andy; Boots, Mike

    2014-05-01

    Host tolerance to infectious disease, whereby hosts do not directly "fight" parasites but instead ameliorate the damage caused, is an important defense mechanism in both plants and animals. Because tolerance to parasite virulence may lead to higher prevalence of disease in a population, evolutionary theory tells us that while the spread of resistance genes will result in negative frequency dependence and the potential for diversification, the evolution of tolerance is instead likely to result in fixation. However, our understanding of the broader implications of tolerance is limited by a lack of fully coevolutionary theory. Here we examine the coevolution of tolerance across a comprehensive range of classic coevolutionary host-parasite frameworks, including equivalents of gene-for-gene and matching allele and evolutionary invasion models. Our models show that the coevolution of host tolerance and parasite virulence does not lead to the generation and maintenance of diversity through either static polymorphisms or through "Red-queen" cycles. Coevolution of tolerance may however lead to multiple stable states leading to sudden shifts in parasite impacts on host health. More broadly, we emphasize that tolerance may change host-parasite interactions from antagonistic to a form of "apparent commensalism," but may also lead to the evolution of parasites that are highly virulent in nontolerant hosts.

  20. Enamel Pearls Implications on Periodontal Disease

    Science.gov (United States)

    Zenóbio, Elton Gonçalves; Vieira, Thaís Ribeiral; Bustamante, Roberta Paula Colen; Gomes, Hayder Egg; Shibli, Jamil Awad; Soares, Rodrigo Villamarin

    2015-01-01

    Dental anatomy is quite complex and diverse factors must be taken into account in its analysis. Teeth with anatomical variations present an increase in the rate of severity periodontal tissue destruction and therefore a higher risk of developing periodontal disease. In this context, this paper reviews the literature regarding enamel pearls and their implications in the development of severe localized periodontal disease as well as in the prognosis of periodontal therapy. Radiographic examination of a patient complaining of pain in the right side of the mandible revealed the presence of a radiopaque structure around the cervical region of lower right first premolar. Periodontal examination revealed extensive bone loss since probing depths ranged from 7.0 mm to 9.0 mm and additionally intense bleeding and suppuration. Surgical exploration detected the presence of an enamel pearl, which was removed. Assessment of the remaining supporting tissues led to the extraction of tooth 44. Local factors such as enamel pearls can lead to inadequate removal of the subgingival biofilm, thus favoring the establishment and progression of periodontal diseases. PMID:26491574

  1. Enamel Pearls Implications on Periodontal Disease

    Directory of Open Access Journals (Sweden)

    Elton Gonçalves Zenóbio

    2015-01-01

    Full Text Available Dental anatomy is quite complex and diverse factors must be taken into account in its analysis. Teeth with anatomical variations present an increase in the rate of severity periodontal tissue destruction and therefore a higher risk of developing periodontal disease. In this context, this paper reviews the literature regarding enamel pearls and their implications in the development of severe localized periodontal disease as well as in the prognosis of periodontal therapy. Radiographic examination of a patient complaining of pain in the right side of the mandible revealed the presence of a radiopaque structure around the cervical region of lower right first premolar. Periodontal examination revealed extensive bone loss since probing depths ranged from 7.0 mm to 9.0 mm and additionally intense bleeding and suppuration. Surgical exploration detected the presence of an enamel pearl, which was removed. Assessment of the remaining supporting tissues led to the extraction of tooth 44. Local factors such as enamel pearls can lead to inadequate removal of the subgingival biofilm, thus favoring the establishment and progression of periodontal diseases.

  2. Language Learning Strategies: Classification and Pedagogical Implication

    Directory of Open Access Journals (Sweden)

    Ag. Bambang Setiyadi

    2001-01-01

    Full Text Available Many studies have been conducted to explore language learning strategies (Rubin, 1975, Naiman et . al ., 1978; Fillmore, 1979; O'Malley et . al ., 1985 and 1990; Politzer and Groarty, 1985; Prokop, 1989; Oxford, 1990; and Wenden, 1991. In the current study a total of 79 university students participating in a 3 month English course participated. This study attempted to explore what language learning strategies successful learners used and to what extent the strategies contributed to success in learning English in Indonesia . Factor analyses, accounting for 62.1 %, 56.0 %, 41.1 %, and 43.5 % of the varience of speaking, listening, reading and writing measures in the language learning strategy questionnaire, suggested that the questionnaire constituted three constructs. The three constructs were named metacognitive strategies, deep level cognitive and surface level cognitive strategies. Regression analyses, performed using scales based on these factors revealed significant main effects for the use of the language learning strategies in learning English, constituting 43 % of the varience in the posttest English achievement scores. An analysis of varience of the gain scores of the highest, middle, and the lowest groups of performers suggested a greater use of metacognitive strategies among successful learners and a greater use of surface level cognitive strategies among unsuccessful learners. Implications for the classroom and future research are also discussed.

  3. Environmental health implications of global climate change

    Energy Technology Data Exchange (ETDEWEB)

    Watson, Robert T.; Patz, Jonathan; Gubler, Duane J.; Parson, Edward A.; Vincent, James H.

    2005-07-01

    This paper reviews the background that has led to the now almost-universally held opinion in the scientific community that global climate change is occurring and is inescapably linked with anthropogenic activity. The potential implications to human health are considerable and very diverse. These include, for example, the increased direct impacts of heat and of rises in sea level, exacerbated air and water-borne harmful agents, and - associated with all the preceding - the emergence of environmental refugees. Vector-borne diseases, in particular those associated with blood-sucking arthropods such as mosquitoes, may be significantly impacted, including redistribution of some of those diseases to areas not previously affected. Responses to possible impending environmental and public health crises must involve political and socio-economic considerations, adding even greater complexity to what is already a difficult challenge. In some areas, adjustments to national and international public health practices and policies may be effective, at least in the short and medium terms. But in others, more drastic measures will be required. Environmental monitoring, in its widest sense, will play a significant role in the future management of the problem. (Author)

  4. Comprehensive Map of Molecules Implicated in Obesity.

    Directory of Open Access Journals (Sweden)

    Jaisri Jagannadham

    Full Text Available Obesity is a global epidemic affecting over 1.5 billion people and is one of the risk factors for several diseases such as type 2 diabetes mellitus and hypertension. We have constructed a comprehensive map of the molecules reported to be implicated in obesity. A deep curation strategy was complemented by a novel semi-automated text mining system in order to screen 1,000 full-length research articles and over 90,000 abstracts that are relevant to obesity. We obtain a scale free network of 804 nodes and 971 edges, composed of 510 proteins, 115 genes, 62 complexes, 23 RNA molecules, 83 simple molecules, 3 phenotype and 3 drugs in "bow-tie" architecture. We classify this network into 5 modules and identify new links between the recently discovered fat mass and obesity associated FTO gene with well studied examples such as insulin and leptin. We further built an automated docking pipeline to dock orlistat as well as other drugs against the 24,000 proteins in the human structural proteome to explain the therapeutics and side effects at a network level. Based upon our experiments, we propose that therapeutic effect comes through the binding of one drug with several molecules in target network, and the binding propensity is both statistically significant and different in comparison with any other part of human structural proteome.

  5. Neurobiology and clinical implications of lucid dreaming.

    Science.gov (United States)

    Mota-Rolim, Sérgio A; Araujo, John F

    2013-11-01

    Several lines of evidence converge to the idea that rapid eye movement sleep (REMS) is a good model to foster our understanding of psychosis. Both REMS and psychosis course with internally generated perceptions and lack of rational judgment, which is attributed to a hyperlimbic activity along with hypofrontality. Interestingly, some individuals can become aware of dreaming during REMS, a particular experience known as lucid dreaming (LD), whose neurobiological basis is still controversial. Since the frontal lobe plays a role in self-consciousness, working memory and attention, here we hypothesize that LD is associated with increased frontal activity during REMS. A possible way to test this hypothesis is to check whether transcranial magnetic or electric stimulation of the frontal region during REMS triggers LD. We further suggest that psychosis and LD are opposite phenomena: LD as a physiological awakening while dreaming due to frontal activity, and psychosis as a pathological intrusion of dream features during wake state due to hypofrontality. We further suggest that LD research may have three main clinical implications. First, LD could be important to the study of consciousness, including its pathologies and other altered states. Second, LD could be used as a therapy for recurrent nightmares, a common symptom of depression and post-traumatic stress disorder. Finally, LD may allow for motor imagery during dreaming with possible improvement of physical rehabilitation. In all, we believe that LD research may clarify multiple aspects of brain functioning in its physiological, altered and pathological states. PMID:23838126

  6. Bowlby's attachment theory: implications for health visiting.

    Science.gov (United States)

    Partis, M

    2000-10-01

    This article reviews the current state of research in attachment theory. It also examines the relations between attachment, child care and development, and the significance of attachment to adult functioning and well-being. It seems likely that humans need close emotional relationships or bonds with others. This need applies particularly to infants, who look to parents or other care givers for love and security. The best-known psychological explanation of this need is attachment theory, which has been influential in increasing our understanding of the early mother-infant relationship, and in the formulation of guidelines for child care (Melhuish, 1998). Good-quality parental care may be difficult to define, and questions remain regarding the nature of child care and the consequences that it can have for later development. This article concludes with a discussion of the possible implications for health-visitor intervention within families, which are intended to improve the quality of the relationship between parents or care givers and the infant.

  7. The clock ambiguity: Implications and new developments

    CERN Document Server

    Albrecht, Andreas

    2008-01-01

    We consider the ambiguity associated with the choice of clock in time reparameterization invariant theories. This arbitrariness undermines the goal of prescribing a fixed set of physical laws, since a change of time variable can completely alter the predictions of the theory. We review the main features of the clock ambiguity and our earlier work on its implications for the emergence of physical laws in a statistical manner. We also present a number of new results: We show that (contrary to suggestions in our earlier work) time independent Hamiltonians may quite generally be assumed for laws of physics that emerge in this picture. We also further explore the degree to which the observed Universe can be well approximated by a random Hamiltonian. We discuss the possibility of predicting the dimensionality of space, and also relate the 2nd derivative of the density of states to the heat capacity of the Universe. This new work adds to the viability of our proposal that strong predictions for physical laws may eme...

  8. The Greek crisis: Causes and implications

    Directory of Open Access Journals (Sweden)

    Vlamis Prodromos

    2010-01-01

    Full Text Available This paper presents and critically discusses the origins and causes of the Greek fiscal crisis and its implications for the euro currency as well as the SEE economies. In the aftermath of the 2007-2009 financial crisis the enormous increase in sovereign debt has emerged as an important negative outcome, since public debt was dramatically increased in an effort by the US and the European governments to reduce the accumulated growth of private debt in the years preceding the recent financial turmoil. Although Greece is the country member of the eurozone that has been in the middle of this ongoing debt crisis, since November 2009 when it was made clear that its budget deficit and mainly its public debt were not sustainable, Greece’s fiscal crisis is not directly linked to the 2007 US subprime mortgage loan market crisis. As a result of this negative downturn the Greek government happily accepted a rescue plan of 110 billion euros designed and financed by the European Union and the IMF. A lengthy austerity programme and a fiscal consolidation plan have been put forward and are to be implemented in the next three years.

  9. Implications of recurrent disturbance for genetic diversity.

    Science.gov (United States)

    Davies, Ian D; Cary, Geoffrey J; Landguth, Erin L; Lindenmayer, David B; Banks, Sam C

    2016-02-01

    Exploring interactions between ecological disturbance, species' abundances and community composition provides critical insights for ecological dynamics. While disturbance is also potentially an important driver of landscape genetic patterns, the mechanisms by which these patterns may arise by selective and neutral processes are not well-understood. We used simulation to evaluate the relative importance of disturbance regime components, and their interaction with demographic and dispersal processes, on the distribution of genetic diversity across landscapes. We investigated genetic impacts of variation in key components of disturbance regimes and spatial patterns that are likely to respond to climate change and land management, including disturbance size, frequency, and severity. The influence of disturbance was mediated by dispersal distance and, to a limited extent, by birth rate. Nevertheless, all three disturbance regime components strongly influenced spatial and temporal patterns of genetic diversity within subpopulations, and were associated with changes in genetic structure. Furthermore, disturbance-induced changes in temporal population dynamics and the spatial distribution of populations across the landscape resulted in disrupted isolation by distance patterns among populations. Our results show that forecast changes in disturbance regimes have the potential to cause major changes to the distribution of genetic diversity within and among populations. We highlight likely scenarios under which future changes to disturbance size, severity, or frequency will have the strongest impacts on population genetic patterns. In addition, our results have implications for the inference of biological processes from genetic data, because the effects of dispersal on genetic patterns were strongly mediated by disturbance regimes. PMID:26839689

  10. Cloud Computing : Research Issues and Implications

    Directory of Open Access Journals (Sweden)

    Marupaka Rajenda Prasad

    2013-01-01

    Full Text Available Cloud computing is a rapidly developing and excellent promising technology. It has aroused the concern of the computer society of whole world. Cloud computing is Internet-based computing, whereby shared information, resources, and software, are provided to terminals and portable devices on-demand, like the energy grid. Cloud computing is the product of the combination of grid computing, distributed computing, parallel computing, and ubiquitous computing. It aims to build and forecast sophisticated service environment with powerful computing capabilities through an array of relatively low-cost computing entity, and using the advanced deployment models like SaaS (Software as a Service, PaaS (Platform as a Service, IaaS (Infrastructure as a Service,HaaS (Hardware as a Service to distribute the powerful computing capacity to end-users. This paper will explore the background and service models and also presents the existing research issues and implications in cloud computing such as security, reliability, privacy, and so on.

  11. Cellular factors implicated in filovirus entry.

    Science.gov (United States)

    Bhattacharyya, Suchita; Hope, Thomas J

    2013-01-01

    Although filoviral infections are still occurring in different parts of the world, there are no effective preventive or treatment strategies currently available against them. Not only do filoviruses cause a deadly infection, but they also have the potential of being used as biological weapons. This makes it imperative to comprehensively study these viruses in order to devise effective strategies to prevent the occurrence of these infections. Entry is the foremost step in the filoviral replication cycle and different studies have reported the involvement of a myriad of cellular factors including plasma membrane components, cytoskeletal proteins, endosomal components, and cytosolic factors in this process. Signaling molecules such as the TAM family of receptor tyrosine kinases comprising of Tyro3, Axl, and Mer have also been implicated as putative entry factors. Additionally, filoviruses are suggested to bind to a common receptor and recent studies have proposed T-cell immunoglobulin and mucin domain 1 (TIM-1) and Niemann-Pick C1 (NPC1) as potential receptor candidates. This paper summarizes the existing literature on filoviral entry with a special focus on cellular factors involved in this process and also highlights some fundamental questions. Future research aimed at answering these questions could be very useful in designing novel antiviral therapeutics. PMID:23365575

  12. Cellular Factors Implicated in Filovirus Entry

    Directory of Open Access Journals (Sweden)

    Suchita Bhattacharyya

    2013-01-01

    Full Text Available Although filoviral infections are still occurring in different parts of the world, there are no effective preventive or treatment strategies currently available against them. Not only do filoviruses cause a deadly infection, but they also have the potential of being used as biological weapons. This makes it imperative to comprehensively study these viruses in order to devise effective strategies to prevent the occurrence of these infections. Entry is the foremost step in the filoviral replication cycle and different studies have reported the involvement of a myriad of cellular factors including plasma membrane components, cytoskeletal proteins, endosomal components, and cytosolic factors in this process. Signaling molecules such as the TAM family of receptor tyrosine kinases comprising of Tyro3, Axl, and Mer have also been implicated as putative entry factors. Additionally, filoviruses are suggested to bind to a common receptor and recent studies have proposed T-cell immunoglobulin and mucin domain 1 (TIM-1 and Niemann-Pick C1 (NPC1 as potential receptor candidates. This paper summarizes the existing literature on filoviral entry with a special focus on cellular factors involved in this process and also highlights some fundamental questions. Future research aimed at answering these questions could be very useful in designing novel antiviral therapeutics.

  13. Extremophile Diatoms: Implications to the Drake Equation

    Science.gov (United States)

    Sterrenburg, Frithjof A. S.; Hoover, Richard B.

    2011-01-01

    Diatoms are unicellular Eukaryotes that (as a group and phylogenetically) are not strictly regarded as extremophiles , since the vast majority of diatoms are mesophilic photoautotrophs. However, among the terrestrial Eukaryotes, diatoms are by far the single group of organisms with the ability to inhabit the greatest range of hostile environments on Earth. They are the dominant eukaryotes in the polar regions; in fumaroles, hot springs and geysers; and in hypersaline and hyperalkaline lakes and pools. Cryophilic species such as Fragilaria sublinearis and Chaetoceras fragilis are able to carry out respiration at extremely low rates at low temperatures in darkness. The Drake Equation refers to the likelihood of there being intelligent life at the technological level of electromagnetic communication. However, consideration of the range of conditions suitable for the habitability of eukaryotic diatoms and prokaryotic extremophiles, the likelihood that life exists elsewhere in the cosmos becomes many orders of magnitude greater than that predicted by the classical Drake Equation. In this paper we review the characteristics of diatoms as eukaryotic extremophiles and consider the implications to adjustments needed to the Drake Equation to assess the possibility that life exists elsewhere in the Universe.

  14. Gamete donation: ethical implications for donors.

    Science.gov (United States)

    Shenfield, Francoise

    1999-01-01

    The interests of gamete donors have only recently been recognized in assisted reproduction; traditionally, the interests of the patients (typically a couple) and the prospective child are paramount. However, assisted reproduction would not be possible without donors, and the simple utilitarian view would be to place their interests first to maximize the availability of the practice. There are several ethical issues on both sides of the donor--recipient equation, some of which are mutual and others are in conflict. For example, the word 'donation' implies there is no payment. Informed consent for donation is essential if the autonomy of the donor is to be respected, and includes information about the results of screening. This is a sensitive issue, especially when pathology is found in a donor who is not being screened for his or her own immediate benefit. Counselling may result in donors refusing to take part, but may also lead to selection by the person recruiting the donors, sometimes as a consequence of examining the motivation of the donor. In this case, the main problem is the ethical basis of the selection process. Other aspects of gamete donation may lead to a conflict of interests between the donor, the recipients and even the prospective child, particularly in terms of anonymity and the information that is made available about the specific circumstances of donation. Implications and support counselling are essential tools in achieving an acceptable balance for all parties involved.

  15. Implications for global energy markets: energy market outlook and implications for gas

    Energy Technology Data Exchange (ETDEWEB)

    Vijver, Walter van de

    1998-07-01

    This paper examines the Shell companies views on the implications for global energy markets, and discusses the belief in precautionary measures such as greenhouse gases emissions limits, the need for the developed countries to take the lead in reducing emissions, and the goal of better living standards globally spread and globally sustainable. The energy future is considered, and the changing world of gas, Shell initiatives in gas development including the Camisea gas and condensate field project in South America, and liquefied natural gas (LNG) developments in India, China and Brazil are considered. (UK)

  16. Implications of the Final Procedures for Evaluating Specific Learning Disabilities

    Science.gov (United States)

    Senf, Gerald M., Ed.

    1978-01-01

    Discussed are some negative implications of the final federal rules for evaluating specific learning disabilities (Federal Register, December 29, 1977), which conceptually redefined learning disabilities to mean an "underachievement." (DLS)

  17. A Macrocosmic Scheme of Cultural Analysis: Implications for Arts Policy

    Science.gov (United States)

    Kaplan, Max

    1975-01-01

    This essay applied the categories, primitive-feudal, industrial, transitional, and post-industrial, to the analysis of the contemporary cultural sphere, in relation to a specific social-technological phenomenon (leisure), with implications for arts policy. (Author/RK)

  18. Implications to Input of English Teaching Brought By Interaction Theory

    Institute of Scientific and Technical Information of China (English)

    李雪; 童心

    2011-01-01

    @@ While discussing Krashen's input theory, it is very easy to find that the problems appear in English teaching are related with the theory, and they have provided beneficial implications for the solu- tions to the problems.

  19. Developments of global capital markets and implications to China

    Institute of Scientific and Technical Information of China (English)

    Mr.KevanWatts

    2004-01-01

    Great changes are happening to global capital markets. Those changes will have extensive influences to China. Therefore, China needs to understand their implications and to reflect those trends in setting a framework of policy to deal with this environment.

  20. Politics of North Korean refugees and regional security implications

    OpenAIRE

    Chang, Jacqueline Danielle

    2009-01-01

    This is the English version of Jacqueline D. Chang's June 2009 Masters Thesis, Politics of North Korean refugees and regional security implication. A Hangul translation version may be found here: http://hdl.handle.net/10945/43808

  1. China English and its Implications for English Teaching in China

    Institute of Scientific and Technical Information of China (English)

    周玉凤

    2007-01-01

    China English is an English variety used by native-Chinese people for communication under specific language environment. This study attempts to outline the objective existence of China English and the implications of its linguistic features for English teaching.

  2. Socio-Economic Implications of New Information Technology

    OpenAIRE

    Page, J.; Lechleuthner, F.; Hervey, L.A.

    1984-01-01

    Socio-Economic Implications of New Information Technology provides not only an exploration of the relevant literature and some guidelines for further, more detailed research, but also some stimulating insights into a host of issues raised by the communications revolution.

  3. Medicare Part D Roulette, Potential Implications of Random..

    Data.gov (United States)

    U.S. Department of Health & Human Services — Medicare Part D Roulette, Potential Implications of Random Assignment and Plan Restrictions Dual-eligible (Medicare and Medicaid) beneficiaries are randomly...

  4. Relevance Theory and Its Implications to Second Language Teaching

    Institute of Scientific and Technical Information of China (English)

    张琪

    2014-01-01

    Relevance Theory Regards human communication as an intentional activity, and as an ostensive-inferential cognitive process. Based on the three key concepts of RT, the present paper shows the implications of this theory in second language teaching.

  5. Co-benefits of CDM projects and policy implications

    OpenAIRE

    Sun, Qie; Xu, Bo; Wennersten, Ronald; Brandt, Nils

    2010-01-01

    This paper aims to study the co-benefits of clean development mechanism (CDM) projects, and further to discuss the policy of its implications. It has been found that many energy-related climate change mitigation (CCM) activities, including CDM projects, are able to produce a significant amount of co-benefits, while the policy implications have been limited. Through co-benefits assessment of Chinese CDM projects, it can be concluded that: (1) there are uncertainties relating to co-benefits ass...

  6. The economic implications of house price capitalization: a synthesis

    OpenAIRE

    Hilber, Christian A. L.

    2015-01-01

    In this article I argue that the extent to which fiscal variables are capitalized into house prices has important economic implications. I synthesize an emerging literature that explores the conditions under which public and private investments and intergovernmental transfers are capitalized into local house prices and the broader implications of such capitalization. The main insights are: (i) House price capitalization is more pronounced in locations with strict regulatory and geographical s...

  7. The Economics Implications of House Price Capitalization: A Synthesis

    OpenAIRE

    Hilber, Christian A. L.

    2011-01-01

    In this article I argue that the extent to which fiscal variables are capitalized into house prices has important economic implications. I synthesize an emerging literature that explores the conditions under which public and private investments and intergovernmental transfers are capitalized into local house prices and the broader implications of such capitalization. The main insights are: (i) House price capitalization is more pronounced in locations with strict regulatory and geographical s...

  8. World Englishes and Its Implications for English Teaching

    Institute of Scientific and Technical Information of China (English)

    宋德龙

    2012-01-01

    <正>The article mainly explores the current concept of World Englishes and its implication for language teaching.After the history and present definition of World Englishes have been discussed in a broad perspective,the author continues to talk about the influence of World Englishes on World Language Education.Chinese English education is then specifically addressed with implications given for both policy-makers and classroom teachers of English.

  9. The Military Coup and its Implications for the Thai Economy

    DEFF Research Database (Denmark)

    Schmidt, Johannes Dragsbæk

    The paper analyses the regional and international implications of the Thai military coup in September 2006. Focus is furthermore  attached to the economic consequences and the geo-political and geo-economic aspects related to the coup.......The paper analyses the regional and international implications of the Thai military coup in September 2006. Focus is furthermore  attached to the economic consequences and the geo-political and geo-economic aspects related to the coup....

  10. Implications of traffic characteristics on interdomain traffic engineering

    OpenAIRE

    Uhlig, Steve

    2004-01-01

    This thesis discusses the implications of the traffic characteristics on interdomain traffic engineering with BGP. We first provide an overview of the interdomain traffic control problem. Then, we present results concerning the characteristics of the interdomain traffic, based on the analysis of real traffic traces gathered from non-transit ASes. We discuss the implications of the topological properties of the traffic on interdomain traffic engineering. Based on this knowledge of the...

  11. Stem cell terminology: practical, theological and ethical implications.

    Science.gov (United States)

    Shanner, Laura

    2002-01-01

    Stem cell policy discussions frequently confuse embryonic and fetal sources of stem cells, and label untested, non-reproductive cloning as "therapeutic." Such misnomers distract attention from significant practical and ethical implications: accelerated research agendas tend to be supported at the expense of physical risks to women, theological implications in a multi-faith community, informed consent for participation in research, and treatment decisions altered by unrealistic expectations.

  12. Empirical studies of software design: Implications for SSEs

    Science.gov (United States)

    Krasner, Herb

    1988-01-01

    Implications for Software Engineering Environments (SEEs) are presented in viewgraph format for characteristics of projects studied; significant problems and crucial problem areas in software design for large systems; layered behavioral model of software processes; implications of field study results; software project as an ecological system; results of the LIFT study; information model of design exploration; software design strategies; results of the team design study; and a list of publications.

  13. Implication ofCorynebacterium species in food’s contamination

    Institute of Scientific and Technical Information of China (English)

    Sana Alibi; Asma Ferjani; Jalel Boukadida

    2016-01-01

    Corynebacteriumspp. are part of the human microbiota. Recently, species of this genus are increasingly implicated in different types of infections especially in immunocompromized and hospitalized patients. The significance of the presence of the genusCorynebacterium in foods is not clearly established. These bacteria may be involved in spoilage or ripening of cheese and meats. This review focused on different researches concerning the implication of Corynebacterium species in food’s contamination.

  14. Shopper marketing implications on communication strategies and actions

    OpenAIRE

    Silveira, Paulo Duarte; Marreiros, Cristina

    2013-01-01

    Comunicação apresentada em 15th IAMB Conference, Lisboa Shopper marketing is an international recent concept and approach to marketing. Since shopper marketing is in the early stages of development, it is also an emerging research field, and consequently questions and challenges acrossall the marketing-mix variables are emerging. This paper addressesshopper marketing implications on one of those variables – communication.Specifically, the purpose of this paper is to study the implications ...

  15. Implications for environmental health of multiple stressors

    Energy Technology Data Exchange (ETDEWEB)

    Mothersill, Carmel; Seymour, Colin [Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, ON, L8S 4K1 (Canada)

    2009-06-01

    Recent insights into the mechanisms underlying the biological effects of low dose effects of ionising radiation have revealed that similar mechanisms can be induced by chemical stressors in the environment. This means that interactions between radiation and chemicals are likely and that the outcomes following mixed exposures to radiation and chemicals may not be predictable for human health, by consideration of single agent effects. Our understanding of the biological effects of low dose exposure has undergone a major paradigm shift. We now possess technologies which can detect very subtle changes in cells due to small exposures to radiation or other pollutants. We also understand much more now about cell communication, systems biology and the need to consider effects of low dose exposure at different hierarchical levels of organisation from molecules up to and including ecosystems. Furthermore we understand, at least in part, some of the mechanisms which drive low dose effects and which perpetuate these not only in the exposed organism but also in its progeny and in certain cases, its kin. This means that previously held views about safe doses or lack of harmful effects cannot be sustained. The International Commission on Radiological Protection (ICRP) and all national radiation and environmental protection organisations have always accepted a theoretical risk and have applied the precautionary principle and the LNT (linear-non-threshold) model which basically says that there is no safe dose of radiation. Therefore even in the absence of visible effects, exposure of people to radiation is strictly limited. This review will consider the historical context and the new discoveries and will focus on evidence for emergent effects after mixed exposures to combined stressors which include ionising radiation. The implications for regulation of low dose exposures to protect human health and environmental security will be discussed.

  16. BUSINESS OFFSHORING IMPLICATIONS ON THE LABOUR MARKET

    Directory of Open Access Journals (Sweden)

    Serghei M RGULESCU

    2012-06-01

    Full Text Available In terms of economic policy, three new aspects are important in the current context of globalization which brings forward new strategies regarding the outsourcing and offshoring of activities and functions of the value chain. These aspects refer to the instant appearance of an offshore transferable function , to the unpredictability of winning and losing functions and to the lowering of competition from the levels of sector, company or professional qualification category to an individual level.. Of the three features, the most problematic for policy makers is the unpredictability of the impact of globalization. For example, in Europe we can not reasonably believe that workers in the most competitive sectors will be in a position of winners, nor that these winners will be the most prepared or trained in analytical functions. Many European workers currently work at prices fixed by the local market and not covered by productivity. But when the competition on functions will expand through globalization outside the country or area, their choices will be either a job loss or a reduction in salary. The question that will be raised ever insistently will be the following: what jobs are more exposed to this new competition? On the one hand, offshoring is on balance positive for Western economies, because it makes domestic companies more competitive. At the same time the material outsourcing is, for most developed economies, much more important than the outsourcing of services and the implications for labor market must be objectively differentiated in the two sectors. On the other hand, if we take into account the amplification of the effects that offshoring already has on the structure and distribution of labor, the socio-economic European policy of labor orientation to the coordinates of a "knowledge based" economy and to the jobs of the "information society" could be wrong.

  17. Implications of conformal invariance in momentum space

    International Nuclear Information System (INIS)

    We present a comprehensive analysis of the implications of conformal invariance for 3-point functions of the stress-energy tensor, conserved currents and scalar operators in general dimension and in momentum space. Our starting point is a novel and very effective decomposition of tensor correlators which reduces their computation to that of a number of scalar form factors. For example, the most general 3-point function of a conserved and traceless stress-energy tensor is determined by only five form factors. Dilatations and special conformal Ward identities then impose additional conditions on these form factors. The special conformal Ward identities become a set of first and second order differential equations, whose general solution is given in terms of integrals involving a product of three Bessel functions (‘triple-K integrals’). All in all, the correlators are completely determined up to a number of constants, in agreement with well-known position space results. In odd dimensions 3-point functions are finite without renormalisation while in even dimensions non-trivial renormalisation in required. In this paper we restrict ourselves to odd dimensions. A comprehensive analysis of renormalisation will be discussed elsewhere. This paper contains two parts that can be read independently of each other. In the first part, we explain the method that leads to the solution for the correlators in terms of triple-K integrals while the second part contains a self-contained presentation of all results. Readers interested only in results may directly consult the second part of the paper

  18. Siderophilic Cyanobacteria: Implications for Early Earth.

    Science.gov (United States)

    Brown, I. I.; Mummey, D.; Sarkisova, S.; Shen, G.; Bryant, D. A.; Lindsay, J.; Garrison, D.; McKay, D. S.

    2006-01-01

    Of all extant environs, iron-depositing hot springs (IDHS) may exhibit the greatest similarity to late Precambrian shallow warm oceans in regards to temperature, O2 gradients and dissolved iron and H2S concentrations. Despite the insights into the ecology, evolutionary biology, paleogeobiochemistry, and astrobiology examination of IDHS could potentially provide, very few studies dedicated to the physiology and diversity of cyanobacteria (CB) inhabiting IDHS have been conducted. Results. Here we describe the phylogeny, physiology, ultrastructure and biogeochemical activity of several recent CB isolates from two different greater Yellowstone area IDHS, LaDuke and Chocolate Pots. Phylogenetic analysis of 16S rRNA genes indicated that 6 of 12 new isolates examined couldn't be placed within established CB genera. Some of the isolates exhibited pronounced requirements for elevated iron concentrations, with maximum growth rates observed when 0.4-1 mM Fe(3+) was present in the media. In light of "typical" CB iron requirements, our results indicate that elevated iron likely represents a salient factor selecting for "siderophilicM CB species in IDHS. A universal feature of our new isolates is their ability to produce thick EPS layers in which iron accumulates resulting in the generation of well preserved signatures. In parallel, siderophilic CB show enhanced ability to etch the analogs of iron-rich lunar regolith minerals and impact glasses. Despite that iron deposition by CB is not well understood mechanistically, we recently obtained evidence that the PS I:PS II ratio is higher in one of our isolates than for other CB. Although still preliminary, this finding is in direct support of the Y. Cohen hypothesis that PSI can directly oxidize Fe(2+). Conclusion. Our results may have implications for factors driving CB evolutionary relationships and biogeochemical processes on early Earth and probably Mars.

  19. Reference drug programs: effectiveness and policy implications.

    Science.gov (United States)

    Schneeweiss, Sebastian

    2007-04-01

    them. This paper summarizes the mechanism and rationale of RDPs, presents evidence of their economic effectiveness and clinical safety, and concludes with some practical implications of implementing RDP policies.

  20. CHO Quasispecies—Implications for Manufacturing Processes

    Directory of Open Access Journals (Sweden)

    Florian M. Wurm

    2013-10-01

    Full Text Available Chinese hamster ovary (CHO cells are a source of multi-ton quantities of protein pharmaceuticals. They are, however, immortalized cells, characterized by a high degree of genetic and phenotypic diversity. As is known for any biological system, this diversity is enhanced by selective forces when laboratories (no sharing of gene pools grow cells under (diverse conditions that are practical and useful. CHO cells have been used in culture for more than 50 years, and various lines of cells are available and have been used in manufacturing. This article tries to represent, in a cursory way, the history of CHO cells, particularly the origin and subsequent fate of key cell lines. It is proposed that the name CHO represents many different cell types, based on their inherent genetic diversity and their dynamic rate of genetic change. The continuing remodeling of genomic structure in clonal or non-clonal cell populations, particularly due to the non-standardized culture conditions in hundreds of different labs renders CHO cells a typical case for “quasispecies”. This term was coined for families of related (genomic sequences exposed to high mutation rate environments where a large fraction of offspring is expected to carry one or more mutations. The implications of the quasispecies concept for CHO cells used in protein manufacturing processes are significant. CHO genomics/transcriptomics may provide only limited insights when done on one or two “old” and poorly characterized CHO strains. In contrast, screening of clonal cell lines, derived from a well-defined starting material, possibly within a given academic or industrial environment, may reveal a more narrow diversity of phenotypes with respect to physiological/metabolic activities and, thus, allow more precise and reliable predictions of the potential of a clone for high-yielding manufacturing processes.

  1. BUSINESS OFFSHORING IMPLICATIONS ON THE LABOUR MARKET

    Directory of Open Access Journals (Sweden)

    SERGHEI MARGULESCU

    2012-05-01

    Full Text Available In terms of economic policy, three new aspects are important in the current context of globalization which brings forward new strategies regarding the outsourcing and offshoring of activities and functions of the value chain. These aspects refer to the instant appearance of an offshore transferable function , to the unpredictability of winning and losing functions and to the lowering of competition from the levels of sector, company or professional qualification category to an individual level. Of the three features, the most problematic for policy makers is the unpredictability of the impact of globalization. For example, in Europe we can not reasonably believe that workers in the most competitive sectors will be in a position of winners, nor that these winners will be the most prepared or trained in analytical functions. Many European workers currently work at prices fixed by the local market and not covered by productivity. But when the competition on functions will expand through globalization outside the country or area, their choices will be either a job loss or a reduction in salary. The question that will be raised ever insistently will be the following: what jobs are more exposed to this new competition? On the one hand, offshoring is on balance positive for Western economies, because it makes domestic companies more competitive. At the same time the material outsourcing is, for most developed economies, much more important than the outsourcing of services and the implications for labor market must be objectively differentiated in the two sectors. On the other hand, if we take into account the amplification of the effects that offshoring already has on the structure and distribution of labor, the socio-economic European policy of labor orientation to the coordinates of a "knowledge based" economy and to the jobs of the "information society" could be wrong.

  2. Definitions of fuel poverty: Implications for policy

    International Nuclear Information System (INIS)

    This paper outlines why the definition of fuel poverty is important in policy formulation and describes how the Government's current definitions evolved from the original concept. It discusses the determination of income and fuel costs and the possibilities for a relative and common European measure. It examines problems inherent in assessing fuel costs as a percentage of income and puts forward the arguments for a ‘budget standard’ approach. The paper illustrates how the size of the problem depends on the definition and chosen threshold and suggests advantages for a rating scale. It illustrates how the income composition and thresholds also govern the distribution of the target populations and the relative importance of the main causal factors, and examines the consequent policy implications. It explores the definition of vulnerable households and the importance of severity and questions whether the UK fuel poverty strategy is targeted at households least able to afford their fuel costs (as the name implies) or primarily those at risk from excess winter and summer mortality and morbidity. Finally, after examining the role of supplementary indicators, it looks at the opportunities for changing the definition and comments on the Government review of the definition and targets. - Highlights: ► There are major failings in the existing official definitions of fuel poverty. ► expressing fuel costs as a percentage of income is a poor indicator of fuel poverty. ► A budget standard approach provides a more consistent, meaningful and fairer measure. ► The scale and nature of the problem changes dramatically with different definitions. ► The definition is crucial to the mix of policies and allocation of resources required.

  3. Tidal river dynamics: Implications for deltas

    Science.gov (United States)

    Hoitink, A. J. F.; Jay, D. A.

    2016-03-01

    Tidal rivers are a vital and little studied nexus between physical oceanography and hydrology. It is only in the last few decades that substantial research efforts have been focused on the interactions of river discharge with tidal waves and storm surges into regions beyond the limit of salinity intrusion, a realm that can extend inland hundreds of kilometers. One key phenomenon resulting from this interaction is the emergence of large fortnightly tides, which are forced long waves with amplitudes that may increase beyond the point where astronomical tides have become extinct. These can be larger than the linear tide itself at more landward locations, and they greatly influence tidal river water levels and wetland inundation. Exploration of the spectral redistribution and attenuation of tidal energy in rivers has led to new appreciation of a wide range of consequences for fluvial and coastal sedimentology, delta evolution, wetland conservation, and salinity intrusion under the influence of sea level rise and delta subsidence. Modern research aims at unifying traditional harmonic tidal analysis, nonparametric regression techniques, and the existing understanding of tidal hydrodynamics to better predict and model tidal river dynamics both in single-thread channels and in branching channel networks. In this context, this review summarizes results from field observations and modeling studies set in tidal river environments as diverse as the Amazon in Brazil, the Columbia, Fraser and Saint Lawrence in North America, the Yangtze and Pearl in China, and the Berau and Mahakam in Indonesia. A description of state-of-the-art methods for a comprehensive analysis of water levels, wave propagation, discharges, and inundation extent in tidal rivers is provided. Implications for lowland river deltas are also discussed in terms of sedimentary deposits, channel bifurcation, avulsion, and salinity intrusion, addressing contemporary research challenges.

  4. Neuroimmunological Implications of AQP4 in Astrocytes

    Science.gov (United States)

    Ikeshima-Kataoka, Hiroko

    2016-01-01

    The brain has high-order functions and is composed of several kinds of cells, such as neurons and glial cells. It is becoming clear that many kinds of neurodegenerative diseases are more-or-less influenced by astrocytes, which are a type of glial cell. Aquaporin-4 (AQP4), a membrane-bound protein that regulates water permeability is a member of the aquaporin family of water channel proteins that is expressed in the endfeet of astrocytes in the central nervous system (CNS). Recently, AQP4 has been shown to function, not only as a water channel protein, but also as an adhesion molecule that is involved in cell migration and neuroexcitation, synaptic plasticity, and learning/memory through mechanisms involved in long-term potentiation or long-term depression. The most extensively examined role of AQP4 is its ability to act as a neuroimmunological inducer. Previously, we showed that AQP4 plays an important role in neuroimmunological functions in injured mouse brain in concert with the proinflammatory inducer osteopontin (OPN). The aim of this review is to summarize the functional implication of AQP4, focusing especially on its neuroimmunological roles. This review is a good opportunity to compile recent knowledge and could contribute to the therapeutic treatment of autoimmune diseases through strategies targeting AQP4. Finally, the author would like to hypothesize on AQP4’s role in interaction between reactive astrocytes and reactive microglial cells, which might occur in neurodegenerative diseases. Furthermore, a therapeutic strategy for AQP4-related neurodegenerative diseases is proposed. PMID:27517922

  5. Neuroimmunological Implications of AQP4 in Astrocytes.

    Science.gov (United States)

    Ikeshima-Kataoka, Hiroko

    2016-01-01

    The brain has high-order functions and is composed of several kinds of cells, such as neurons and glial cells. It is becoming clear that many kinds of neurodegenerative diseases are more-or-less influenced by astrocytes, which are a type of glial cell. Aquaporin-4 (AQP4), a membrane-bound protein that regulates water permeability is a member of the aquaporin family of water channel proteins that is expressed in the endfeet of astrocytes in the central nervous system (CNS). Recently, AQP4 has been shown to function, not only as a water channel protein, but also as an adhesion molecule that is involved in cell migration and neuroexcitation, synaptic plasticity, and learning/memory through mechanisms involved in long-term potentiation or long-term depression. The most extensively examined role of AQP4 is its ability to act as a neuroimmunological inducer. Previously, we showed that AQP4 plays an important role in neuroimmunological functions in injured mouse brain in concert with the proinflammatory inducer osteopontin (OPN). The aim of this review is to summarize the functional implication of AQP4, focusing especially on its neuroimmunological roles. This review is a good opportunity to compile recent knowledge and could contribute to the therapeutic treatment of autoimmune diseases through strategies targeting AQP4. Finally, the author would like to hypothesize on AQP4's role in interaction between reactive astrocytes and reactive microglial cells, which might occur in neurodegenerative diseases. Furthermore, a therapeutic strategy for AQP4-related neurodegenerative diseases is proposed. PMID:27517922

  6. Discovering indigenous science: Implications for science education

    Science.gov (United States)

    Snively, Gloria; Corsiglia, John

    2001-01-01

    Indigenous science relates to both the science knowledge of long-resident, usually oral culture peoples, as well as the science knowledge of all peoples who as participants in culture are affected by the worldview and relativist interests of their home communities. This article explores aspects of multicultural science and pedagogy and describes a rich and well-documented branch of indigenous science known to biologists and ecologists as traditional ecological knowledge (TEK). Although TEK has been generally inaccessible, educators can now use a burgeoning science-based TEK literature that documents numerous examples of time-proven, ecologically relevant, and cost effective indigenous science. Disputes regarding the universality of the standard scientific account are of critical importance for science educators because the definition of science is a de facto gatekeeping device for determining what can be included in a school science curriculum and what cannot. When Western modern science (WMS) is defined as universal it does displace revelation-based knowledge (i.e., creation science); however, it also displaces pragmatic local indigenous knowledge that does not conform with formal aspects of the standard account. Thus, in most science classrooms around the globe, Western modern science has been taught at the expense of indigenous knowledge. However, because WMS has been implicated in many of the world's ecological disasters, and because the traditional wisdom component of TEK is particularly rich in time-tested approaches that foster sustainability and environmental integrity, it is possible that the universalist gatekeeper can be seen as increasingly problematic and even counter productive. This paper describes many examples from Canada and around the world of indigenous people's contributions to science, environmental understanding, and sustainability. The authors argue the view that Western or modern science is just one of many sciences that need to be

  7. Widening economic & social disparities: implications for India.

    Science.gov (United States)

    Kurian, N J

    2007-10-01

    -bound manner, there could be serious adverse implications for the Indian economy, society and politics.

  8. Implications for environmental health of multiple stressors

    International Nuclear Information System (INIS)

    Recent insights into the mechanisms underlying the biological effects of low dose effects of ionising radiation have revealed that similar mechanisms can be induced by chemical stressors in the environment. This means that interactions between radiation and chemicals are likely and that the outcomes following mixed exposures to radiation and chemicals may not be predictable for human health, by consideration of single agent effects. Our understanding of the biological effects of low dose exposure has undergone a major paradigm shift. We now possess technologies which can detect very subtle changes in cells due to small exposures to radiation or other pollutants. We also understand much more now about cell communication, systems biology and the need to consider effects of low dose exposure at different hierarchical levels of organisation from molecules up to and including ecosystems. Furthermore we understand, at least in part, some of the mechanisms which drive low dose effects and which perpetuate these not only in the exposed organism but also in its progeny and in certain cases, its kin. This means that previously held views about safe doses or lack of harmful effects cannot be sustained. The International Commission on Radiological Protection (ICRP) and all national radiation and environmental protection organisations have always accepted a theoretical risk and have applied the precautionary principle and the LNT (linear-non-threshold) model which basically says that there is no safe dose of radiation. Therefore even in the absence of visible effects, exposure of people to radiation is strictly limited. This review will consider the historical context and the new discoveries and will focus on evidence for emergent effects after mixed exposures to combined stressors which include ionising radiation. The implications for regulation of low dose exposures to protect human health and environmental security will be discussed.

  9. Widening economic & social disparities: implications for India.

    Science.gov (United States)

    Kurian, N J

    2007-10-01

    -bound manner, there could be serious adverse implications for the Indian economy, society and politics. PMID:18032812

  10. Implications of Fast Reactor Transuranic Conversion Ratio

    Energy Technology Data Exchange (ETDEWEB)

    Steven J. Piet; Edward A. Hoffman; Samuel E. Bays

    2010-11-01

    Theoretically, the transuranic conversion ratio (CR), i.e. the transuranic production divided by transuranic destruction, in a fast reactor can range from near zero to about 1.9, which is the average neutron yield from Pu239 minus 1. In practice, the possible range will be somewhat less. We have studied the implications of transuranic conversion ratio of 0.0 to 1.7 using the fresh and discharge fuel compositions calculated elsewhere. The corresponding fissile breeding ratio ranges from 0.2 to 1.6. The cases below CR=1 (“burners”) do not have blankets; the cases above CR=1 (“breeders”) have breeding blankets. The burnup was allowed to float while holding the maximum fluence to the cladding constant. We graph the fuel burnup and composition change. As a function of transuranic conversion ratio, we calculate and graph the heat, gamma, and neutron emission of fresh fuel; whether the material is “attractive” for direct weapon use using published criteria; the uranium utilization and rate of consumption of natural uranium; and the long-term radiotoxicity after fuel discharge. For context, other cases and analyses are included, primarily once-through light water reactor (LWR) uranium oxide fuel at 51 MWth-day/kg-iHM burnup (UOX-51). For CR<1, the heat, gamma, and neutron emission increase as material is recycled. The uranium utilization is at or below 1%, just as it is in thermal reactors as both types of reactors require continuing fissile support. For CR>1, heat, gamma, and neutron emission decrease with recycling. The uranium utilization exceeds 1%, especially as all the transuranic elements are recycled. exceeds 1%, especially as all the transuranic elements are recycled. At the system equilibrium, heat and gamma vary by somewhat over an order of magnitude as a function of CR. Isotopes that dominate heat and gamma emission are scattered throughout the actinide chain, so the modest impact of CR is unsurprising. Neutron emitters are preferentially found

  11. Profiling of genetic switches using boolean implications in expression data.

    Science.gov (United States)

    Çakır, Mehmet Volkan; Binder, Hans; Wirth, Henry

    2014-01-01

    Correlation analysis assuming coexpression of the genes is a widely used method for gene expression analysis in molecular biology. Yet growing extent, quality and dimensionality of the molecular biological data permits emerging, more sophisticated approaches like Boolean implications. We present an approach which is a combination of the SOM (self organizing maps) machine learning method and Boolean implication analysis to identify relations between genes, metagenes and similarly behaving metagene groups (spots). Our method provides a way to assign Boolean states to genes/metagenes/spots and offers a functional view over significantly variant elements of gene expression data on these three different levels. While being able to cover relations between weakly correlated entities Boolean implication method also decomposes these relations into six implication classes. Our method allows one to validate or identify potential relationships between genes and functional modules of interest and to assess their switching behaviour. Furthermore the output of the method renders it possible to construct and study the network of genes. By providing logical implications as updating rules for the network it can also serve to aid modelling approaches.

  12. Deforming Etna's Basement: Implications for Edifice stability.

    Science.gov (United States)

    Bakker, Richard; Benson, Philip; Vinciguerra, Sergio

    2013-04-01

    active (>500 ˚C). As shown by Gudmundsson [2011] a large contrast in mechanical properties between two formations could cause dyke arrest or deflection. Contacts between the Comiso Limestone (overall ductile at depth) and extruded basalt flows (overall brittle) could very well facilitate such a locality, and such 'layering' will form part of future laboratory investigations. References: Chiodini, G., S. Caliro, A. Aiuppa, R. Avino, D. Granieri, R. Moretti, and F. Parello (2011), First 13C/12C isotopic characterisation of volcanic plume CO2, Bulletin of Volcanology, 73(5), 531-542. Gudmundsson, A. (2011), Deflection of dykes into sills at discontinuities and magma-chamber formation, Tectonophysics, 500(1-4), 50-64. Heap, M. J., S. Mollo, S. Vinciguerra, Y. Lavallée, K. U. Hess, D. B. Dingwell, P. Baud, and G. Iezzi (2013), Thermal weakening of the carbonate basement under Mt. Etna volcano (Italy): Implications for volcano instability, Journal of Volcanology and Geothermal Research, 250(0), 42-60. Mollo, S., S. Vinciguerra, G. Iezzi, A. Iarocci, P. Scarlato, M. J. Heap, and D. B. Dingwell (2011), Volcanic edifice weakening via devolatilization reactions, Geophysical Journal International, 186(3), 1073-1077. Tibaldi, A., and G. Groppelli (2002), Volcano-tectonic activity along structures of the unstable NE flank of Mt. Etna (Italy) and their possible origin, Journal of Volcanology and Geothermal Research, 115(3-4), 277-302.

  13. Implications of NEAR results for asteroid structure

    Science.gov (United States)

    Cheng, A.

    . MathildeSs high porosity may lead to compressional cratering, which may explain how these giant craters were emplaced, but does this process apply to Eros? Moreover, a 20-km long scarp and polygonal craters have been reported on Mathilde, indicating that it is not completely strengthless and that at least one of its structural components appears coherent over a few tens of km. Still, available evidence suggests that MathildeSs interior is more severely damaged by collisions than the interior of Eros.Recent work has focused on ponded deposits of regolith on Eros. These deposits appear to have been emplaced by fluid-like motion. Electrostatic levitation and seismic shaking have been proposed as mechanisms to mobilize particulates. Because of the low surface gravity on Eros, a low amplitude of seismic shaking suffices to cause slope failures and degradation of topography. A seismic shaking model (Cheng et al. 2002) predicts that ponds should form readily on Eros but not on much larger bodies like the Moon, where ponds are not observed. Seismic shaking may contribute to the degraded appearance of many craters and topographic features on Eros. Implicit in this model is that seismic waves are transmitted globally through Eros. Britt and Consolmagno (2001) suggested that macroscopic fractures within the interior of an asteroid should be void, because fines should be retained by friction near the surface and cannot fall into the interior even if an open path is available. Void, macroscopic fractures, which may be through-going in the case of Eros, would have profound implications for mitigation. I will argue instead that fractures within an asteroid should be filled with particulates, because friction forces should not prevent particles from falling through cracks.2

  14. The whale barnacle Cryptolepas rhachianecti (Cirripedia: Coronulidae), a phoront of the grey whale Eschrichtius robustus (Cetacea: Eschrichtiidae), from a sandy beach in The Netherlands.

    Science.gov (United States)

    Bosselaers, Mark; Collareta, Alberto

    2016-08-22

    An isolated compartment of a whale barnacle is herein described from Recent beach deposits in Zoutelande (Walcheren, The Netherlands). This specimen is identified as belonging to the extant coronulid species Cryptolepas rhachianecti, currently known as an epizoic symbiont of the grey whale Eschrichtius robustus. This find represents the first occurrence of C. rhachianecti outside the North Pacific, and the first one as a (sub)fossil. In view of the fact that E. robustus, which is currently confined to the North Pacific, is known as a subfossil from the northeastern Atlantic between late Late Pleistocene (c. 45,000 years ago) and historical (c. 1700 AD) times, we propose a similar (late Quaternary) age for the isolated compartment. The find indicates that the extinct late Quaternary northeastern Atlantic population of E. robustus was infected by Cryptolepas rhachianecti. Our find is, therefore, compatible with the hypothesis of an ancient grey whale migration route running between the subtropical/temperate waters of the northeast Atlantic (or Mediterranean Basin), and the cold waters of the Baltic Sea (or southern Arctic Ocean), through the southern North Sea. Finally, we discuss the systematic placement of the fossil barnacle species Cryptolepas murata and propose the possibility of its removal from the genus Cryptolepas pending further investigations.

  15. Three-dimensional computer-aided reconstruction of FMRFamide immunopositive neuron distribution in the ventral ganglion of the barnacle Balanus amphitrite (Cirripedia, Crustacea

    Directory of Open Access Journals (Sweden)

    L Gallus

    2009-12-01

    Full Text Available We have implemented a simple program to solve three of the problems related to 3D reconstruction (3D-Rec of soft tissues: alignment of sections, distortions, and estimation of the spatial position of elements of interest inside the tissues. As a model, we chose the distribution of FMRFamide-like immunopositive neurons in the ventral ganglion of the barnacle Balanus amphitrite collected during different seasonal periods. Images of immunostained sections were acquired by means of a CCDcamera- equipped microscope and a PC and the reference points were taken inside the sections. The FMRFamide-like immunopositive neurons detected in the barnacle ventral ganglion were grouped into four different classes according to size, shape and staining intensity. More numerous FMRFamide- like immunopositive neurons were detected in the autumn-collected barnacle than in the summer counterpart. The two 3D reconstructions obtained from transverse and longitudinal ventral ganglion sections were efficaciously compared after 90° rotation of one of them. Comparison of these two 3D-Rec suggests the presence of at least two groups of FMRFamide-like immunopositive neurons that are seasonally-related and probably involved in reproduction.

  16. Antifouling effect of bioactive compounds from marine sponge Acanthella elongata and different species of bacterial film on larval attachment of Balanus amphitrite (cirripedia, crustacea

    Directory of Open Access Journals (Sweden)

    Viswambaran Ganapiriya

    2012-06-01

    Full Text Available The antifouling activity of bioactive compounds from marine sponge Acanthella elongata (Dendy and five species of bacterial biofilm were studied. Larvae of Balanus amphitrite (Cyprids and nauplii were used to monitor the settlement inhibition and the extent to which inhibition was due to toxicity. The crude extract and partially purified fractions of A.elongata showed significant inhibition over the settlement individually, and with the interaction of bacterial species. No bacterial film stimulated the barnacle settlement. The high but variable levels of antifouling activity in combination with less amount of toxicity showed the potential of these metabolites in environmentally-friendly antifouling preparations.

  17. Preliminary results on the anatomy of the larval musculature of Balanus improvisus (Darwin, 1854) (Crustacea: Cirripedia: Thecostraca) using phalloidin staining in combination with confocal laserscanning microscopy

    DEFF Research Database (Denmark)

    Semmler, Henrike; Høeg, Jens Thorvald; Scholtz, Gerhard;

    2006-01-01

    The anatomy of the larval muscular systems in Balanus improvisus (Darwin, 1854) was investigated by using phalloidin staining to visualize filamentous F-actin in combination with confocal laser scanning microscopy (CLSM). The larval musculature contains an anterior muscle complex associated with ...

  18. SYMPOSIUM - MACRONUTRIENT UTILIZATION DURING EXERCISE: IMPLICATIONS FOR PERFORMANCE AND SUPPLEMENTATION

    Directory of Open Access Journals (Sweden)

    Darryn S. Willoughby

    2004-09-01

    Full Text Available The review articles constitute a mini-symposium entitled "Macronutrient Utilization During Exercise: Implications for Performance and Supplementation" that were recently presented at the 2004 annual conference of the International Society of Sports Nutrition in Las Vegas, NV. Much controversy often surrounds macronutrient intake, utilization, and subsequent metabolism regarding exercise and athletic performance. Furthermore, the role of macronutrient supplementation with the specificintent of improving body composition and exercise performance by way of nutrient timing is also an important issue. As such, the articles provide a comprehensive overview of metabolic and performance-enhancing implications regarding carbohydrate, fat, and protein.

  19. The estrogen hypothesis of schizophrenia implicates glucose metabolism

    DEFF Research Database (Denmark)

    Olsen, Line; Hansen, Thomas; Jakobsen, Klaus D;

    2008-01-01

    . We undertook these challenges by using an established clinical paradigm, the estrogen hypothesis of schizophrenia, as the criterion to select candidates among the numerous genes experimentally implicated in schizophrenia. Bioinformatic tools were used to build and priorities the signaling networks...... implicated by the candidate genes resulting from the estrogen selection. We identified ten candidate genes using this approach that are all active in glucose metabolism and particularly in the glycolysis. Thus, we tested the hypothesis that variants of the glycolytic genes are associated with schizophrenia...

  20. The CH/π hydrogen bond: Implication in chemistry

    Science.gov (United States)

    Nishio, M.

    2012-06-01

    The CH/π hydrogen bond is the weakest extreme of hydrogen bonds that occurs between a soft acid CH and a soft base π-system. Implication in chemistry of the CH/π hydrogen bond includes issues of conformation, crystal packing, and specificity in host/guest complexes. The result obtained by analyzing the Cambridge Structural Database is reviewed. The peculiar axial preference of isopropyl group in α-phellandrene and folded conformation of levopimaric acid have been explained in terms of the CH/π hydrogen bond, by high-level ab initio MO calculations. Implication of the CH/π hydrogen bond in structural biology is also discussed, briefly.

  1. A Brief Discussion on Pragmatic Analysis and Classroom Implications

    Institute of Scientific and Technical Information of China (English)

    殷月洪

    2012-01-01

    Pragmatics is the study of language in use; pragmatic analysis is one of the research perspectives in pragmatic studies. So far, a number of researchers have developed different theories to investigate how language is used in different contexts. Among these theories are Speech Act, Cooperative Principle, and Politeness Principle, etc. These theories have helped the development of pragmatic analysis and its implications are evident in language teaching and learning. This paper is an effort to briefly outline some theories in pragmatic analysis and the classroom implications.

  2. Rethinking the Concept of Acculturation: Implications for Theory and Research

    Science.gov (United States)

    Schwartz, Seth J.; Unger, Jennifer B.; Zamboanga, Byron L.; Szapocznik, Jose

    2010-01-01

    This article presents an expanded model of acculturation among international migrants and their immediate descendants. Acculturation is proposed as a multidimensional process consisting of the confluence among heritage-cultural and receiving-cultural practices, values, and identifications. The implications of this reconceptualization for the…

  3. Vitamin D Status of College Students: Implications for Health Leaders

    Science.gov (United States)

    Cress, Eileen McKenna

    2014-01-01

    Vitamin D deficiency is considered to be a pandemic with implications for compromised bone health and other chronic diseases. Few studies have examined vitamin D status in college-aged individuals where prevention of future health consequences is still possible. Serum vitamin D 25(OH)D status and vitamin D intake were examined in 98 college…

  4. Sexual Addiction and the Internet: Implications for Gay Men

    Science.gov (United States)

    Dew, Brian J.; Chaney, Michael P.

    2004-01-01

    The authors present an overview of sexual addiction and explore the relationship between Internet use and sexual compulsivity. The role of Internet use in gay men's sexual behavior is described. Implications for the counseling profession are discussed, and a clinical case study is presented.

  5. Implications of Implementing Web 2.0 on Education

    Science.gov (United States)

    Valerio, Gabriel; Valenzuela, Ricardo

    2013-01-01

    The Knowledge Society has altered the way humanity works, learns and amuses itself; from here the rise of the so called e-learning, an educational modality whose "innovation" has been questioned because of the tendency to simulate traditional ways to educate. This paper explores the concept of e-learning 2.0, the implications of…

  6. Marital Conflict Behaviors and Implications for Divorce over 16 Years

    Science.gov (United States)

    Birditt, Kira S.; Brown, Edna; Orbuch, Terri L.; McIlvane, Jessica M.

    2010-01-01

    This study examined self-reported marital conflict behaviors and their implications for divorce. Husbands and wives (N = 373 couples; 47% White American, 53% Black American) reported conflict behaviors in Years 1, 3, 7, and 16 of their marriages. Individual behaviors (e.g., destructive behaviors) and patterns of behaviors between partners (e.g.,…

  7. The Privatization of NTIS: What Are the Implications?

    Science.gov (United States)

    Moody, Marilyn

    1986-01-01

    Discussion of various alternatives for privatization of the National Technical Information Service (NTIS) being studied by the Department of Commerce highlights issues identified in the April 1986 notice in the Federal Register, representative users' comments, the range of NTIS services and products, and the implications of privatization for…

  8. Exposure to Polychlorinated Biphenyls (PCBs): Implications for School Psychologists

    Science.gov (United States)

    Cook-Cottone, Catherine

    2004-01-01

    Pediatric exposure to polychlorinated biphynels (PCBs) is a national health concern with significant implications for school psychologists. According to the healthcare collaboration model, the school psychologist plays a key role in the provision of services to children affected by environmental teratogens. To effectively function as healthcare…

  9. The constitutional implications of the rise of the SNP

    OpenAIRE

    McHarg, Aileen

    2015-01-01

    The UK Constitutional Law Association blog has asked constitutional lawyers to review the main party manifestos ahead of the May elections, drawing out key constitutional proposals. Below Aileen McHarg discussed the constitutional implications of the rise of the SNP.

  10. Philosophical implications and multidisciplinary challenges of moral physiology

    NARCIS (Netherlands)

    Schleim, Stephan; Schirmann, Felix

    2011-01-01

    Neuroethics deals with the normative implications of advances and new technology of neuroscience. Some scholars argue that experiments on moral judgment might allow solutions to moral problems in the future or already nowadays. We discuss this research under the label of moral physiology to delineat

  11. Hotel Employees' Japanese Language Experiences: Implications and Suggestions.

    Science.gov (United States)

    Makita-Discekici, Yasuko

    1998-01-01

    Analyzes the Japanese language learning experiences of 13 hotel employees in Guam. Results of the study present implications and suggestions for a Japanese language program for the hotel industry. The project began as a result of hotel employees frustrations when they were unable to communicate effectively with their Japanese guests. (Auth/JL)

  12. First Amendment Implications of Harassment Rules to Be Studied.

    Science.gov (United States)

    Jaschik, Scott

    1994-01-01

    The Department of Education, criticized by colleges for its guidelines on investigating racial harassment and hate-speech charges, will issue a new policy on First Amendment implications of such inquiries. A major issue is school responsibility for racial harassment by diverse populations over whom colleges may have little control. (MSE)

  13. General Relativistic Dynamics of Irrotational Dust Cosmological Implications

    CERN Document Server

    Matarrese, S; Sáez, D; Matarrese, Sabino; Pantano, Ornella; Saez, Diego

    1994-01-01

    The non--linear dynamics of cosmological perturbations of an irrotational collisionless fluid is analyzed within General Relativity. Relativistic and Newtonian solutions are compared, stressing the different role of boundary conditions in the two theories. Cosmological implications of relativistic effects, already present at second order in perturbation theory, are studied and the dynamical role of the magnetic part of the Weyl tensor is elucidated.

  14. Developmental Needs of Middle School Students: Implications for Counselors.

    Science.gov (United States)

    Johnson, Wanda; Kottman, Terry

    1992-01-01

    Presents information provided by Gesell Institute of Child Development on behavioral and attitudinal components expected at each age level for middle school students to help school counselors meet the developmental needs of these students. Developmental considerations are discussed; and implications for counselors are explored for 10, 11, 12, 13,…

  15. Safeguarding and Protecting Children in Maternity Services: Implications for Practice

    Science.gov (United States)

    Lazenbatt, Anne; Greer, Jean

    2009-01-01

    This article debates the issues involved in safeguarding and protecting children in maternity services and offers implications for professional practice. Midwives and other staff who work as members of the maternity team have a safeguarding role to play in the identification of babies and children who have been abused, or are at risk of abuse, and…

  16. Training Implications of Harmful Effects of Psychological Treatments

    Science.gov (United States)

    Castonguay, Louis G.; Boswell, James F.; Constantino, Michael J.; Goldfried, Marvin R.; Hill, Clara E.

    2010-01-01

    The goal of this article is to delineate training implications regarding harmful effects associated with psychotherapy. The authors strongly recommend that trainees be made aware of (and encouraged to examine carefully) the potentially harmful treatments that have been recently identified (Lilienfeld, 2007). Consistent with a broad perspective on…

  17. Multiple Intelligence Theory for Gifted Education: Criticisms and Implications

    Science.gov (United States)

    Calik, Basak; Birgili, Bengi

    2013-01-01

    This paper scrutinizes giftedness and gifted learners under the implications of multiple intelligence theory with regard to coaching young scientists. It is one of the pluralistic theories toward intelligence while supporting to view individuals as active participants during teaching and learning processes which correspond with the applications of…

  18. TG Grammar's Implications for the Foreign Language Teaching

    Institute of Scientific and Technical Information of China (English)

    殷彩

    2009-01-01

    Chomsky's Transformational-Generative (TG) grammar is another revolution to linguistics after Saussure's strueturalism, and it plays an important role in the modem linguistics. Introducing the research perspective and method of TG grammar, this paper analyses its implications for the foreign language teaching.

  19. Response to "Violence in Our Schools: Implications for Teacher Education."

    Science.gov (United States)

    Marvin, Diane; Mahlios, Marc; Hadadian, Azar; Spitznagel, Ronald

    2000-01-01

    Three responses to an article on implications for teacher education of school violence examine: (1) teacher educators' roles in preparing teachers to detect problems in students; (2) the need for family involvement (because trying to reach students in school is too late); and (3) reasons for school violence (family influence, parent…

  20. Using Cultural Diversity in Teaching Economics: Global Business Implications

    Science.gov (United States)

    Mitry, Darryl J.

    2008-01-01

    Globalization and increasing cross-cultural interactivity have implications for education in general and may also present valuable pedagogical opportunities in the practice of teaching economics for business students. Therefore, the author investigated this proposition and offers some empirical observations from research and teaching experiments.…

  1. Azerbaijan Demographic Change : Implications for Social Policy and Poverty

    OpenAIRE

    World Bank

    2011-01-01

    This note provides an overview of demographic changes in Azerbaijan and their policy implications. Azerbaijan's population is younger than the populations of most countries in the region. It is estimated that the population in Azerbaijan will increase from about 7.2 million in 1990 to 10.6 million by 2050. Nevertheless, Azerbaijan is beginning to experience the aging of its population, aft...

  2. Financial Implications of Implementing an E-Learning Project

    Science.gov (United States)

    Sharma, Kunal

    2011-01-01

    Purpose: This paper aims to outline the financial implications, while deploying information and communication technologies for implementing e-learning, and to elucidate them, while implementing an e-learning project in a conventional university environment. Design/methodology/approach: The paper is a descriptive account of the various cost factors…

  3. Implications for Child Bilingual Acquisition, Optionality and Transfer

    Science.gov (United States)

    Serratrice, Ludovica

    2014-01-01

    Amaral & Roeper's Multiple Grammars (MG) proposal offers an appealingly simple way of thinking about the linguistic representations of bilingual speakers. This article presents a commentary on the MG language acquisition theory proposed by Luiz Amaral and Tom Roeper in this issue, focusing on the theory's implications for child…

  4. Pluricentric Views towards English and Implications for ELT in China

    Science.gov (United States)

    Jianli, Liang

    2015-01-01

    Descriptions of the classifications or models of English language have been proposed by a number of scholars who attempt to explain the differences in the ways English is used in different localities. This paper reviews three models of classification of English language, with an aim of drawing implications on how English Language Teaching (ELT) in…

  5. A gene expression signature for RSV: clinical implications and limitations.

    Directory of Open Access Journals (Sweden)

    Peter J M Openshaw

    2013-11-01

    Full Text Available Peter Openshaw discusses the challenges in advancing respiratory syncytial virus (RSV treatments and the implications of a study by Mejias and colleagues using a newly identified gene signature for diagnosis and prediction of RSV severity. Please see later in the article for the Editors' Summary.

  6. Modes of Funding Nigerian Universities and the Implications on Performance

    Science.gov (United States)

    Ogbogu, Christiana O.

    2011-01-01

    This paper examined the modes of funding Nigerian universities with a view to assessing their adequacy and effectiveness. The implications of the mechanisms of funding on university performance were investigated. The history of university funding in Nigeria was explored in order to determine the causes of shift in financing the system since 1948…

  7. Atrial Arrhythmias and Their Implications for Space Flight - Introduction

    Science.gov (United States)

    Polk, J. D.; Barr, Y. R.; Bauer, P.; Hamilton, D. R.; Kerstman, E.; Tarver, B.

    2010-01-01

    This panel will discuss the implications of atrial arrhythmias in astronauts from a variety of perspectives; including historical data, current practices, and future challenges for exploration class missions. The panelists will present case histories, outline the evolution of current NASA medical standards for atrial arrhythmias, discuss the use of predictive tools, and consider potential challenges for current and future missions.

  8. LHCb results on flavour physics and implications to BSM

    CERN Document Server

    Langenbruch, C

    2014-01-01

    LHCb is a dedicated flavour physics experiment at the LHC. Precision measurements of CP violation and the study of rare decays of hadrons containing beauty and charm quarks constitute powerful searches for New Physics. A selection of recent LHCb results and their implications to physics beyond the Standard Model are discussed.

  9. The Bologna Process: Perspectives and Implications for the Russian University

    Science.gov (United States)

    Telegina, Galina; Schwengel, Hermann

    2012-01-01

    This article draws on the discourses of educational policy in Europe to focus on the implications of the Bologna Process for higher education in Russia. The Bologna Process, as a multi-dimensional discourse involving a variety of social actors, reflects some of the complexities and contradictions of globalisation, in many local cases evoking…

  10. Examining Female Life Events: Implications for Counselors and Educators

    Science.gov (United States)

    Schwiebert, Valerie; Alston, Anne; Bradford, Caroline; Sealander, Karen A.

    2008-01-01

    This article reports the findings of a study examining the impact of female life events (menarche, "the sex talk", and loss of virginity) on women. Fifty-one women from 2 universities responded to a questionnaire containing quantitative and qualitative items. Discussion and implications for counseling girls and women are presented. (Contains 2…

  11. Implicazioni del Nuovo Bilinguismo (Implications of New Bilingualism).

    Science.gov (United States)

    Caso, Adolph

    This article discusses the implications of the present trend towards bilingual education in the United States. Special attention is paid to the Commonwealth of Massachusetts, which has established bilingual programs in all of its public schools. Included among the possible effects of the new law are the following points of interest: (1) Students…

  12. Do TQM interventions change management culture? Findings and implications.

    Science.gov (United States)

    Gerowitz, M B

    1998-01-01

    This study assesses the impact of TQM/CQI interventions on the culture and performance of top management teams. The findings suggest culture is related to performance but that TQM/CQI interventions are not associated with either performance or culture change. Implications for additional research and for practice are discussed.

  13. Implications of "Amae" for HIV Risk in Japanese Young Adults.

    Science.gov (United States)

    Onuoha, Francis N.; Munakata, Tsunetsugu

    2005-01-01

    Assertiveness, defined as perceived confidence to express true feelings in interpersonal relationships, has been reported to correlate with HIV risk avoidance. However, Japanese social structure encourages "amae" or self-repression. The present study investigated the implications of "amae" for HIV risk avoidance among Japanese university students.…

  14. Discussion Forum--Population Theories: Their Implications on Population Education.

    Science.gov (United States)

    Population Education in Asia and the Pacific Newsletter, 1983

    1983-01-01

    Contends that unless population education programs have a clear conceptual framework built upon a consistent set of population theories, they will remain merely as appendices to established school projects. Several population theories and their implications for population education are described. These include Malthusian demographic transition,…

  15. Considering Shame and Its Implications for Student Learning

    Science.gov (United States)

    Johnson, Diane Elizabeth

    2012-01-01

    Research evidence is accumulating to suggest that shame can be implicated in important ways in student adjustment to the learning environment. Student survey data spring-fall 2010 suggest that shame is associated with variables thought to be closely related to student learning--sense of community, burnout and achievement goals--and underline the…

  16. Carol Gilligan's Perspectives and Staff Supervision: Implications for the Practitioner.

    Science.gov (United States)

    Porterfield, William D.; Pressprich, Sybil T.

    1988-01-01

    Applies Gilligan's perspectives on gender identity to the supervisory process for resident advisers in an effort to help residence staff become aware of gender differences that affect performance. Discusses implications of gender identity in areas of community development, policy enforcement, teamwork, decision-making, and relationship formation.…

  17. The interface of depression and cardiovascular disease: therapeutic implications.

    Science.gov (United States)

    Seligman, Fred; Nemeroff, Charles B

    2015-05-01

    Patients with major depression are at an increased risk for developing cardiovascular disease, respond more poorly to treatment, and exhibit worse outcomes, including increased morbidity and mortality. This article reviews the relationship between depression and heart disease, with an emphasis on epidemiology, biological substrates that likely underlie this relationship, and implications for treatment. PMID:25809518

  18. Implications of Hegel's Theories of Language on Second Language Teaching

    Science.gov (United States)

    Wu, Manfred

    2016-01-01

    This article explores the implications of Hegel's theories of language on second language (L2) teaching. Three among the various concepts in Hegel's theories of language are selected. They are the crucial role of intersubjectivity; the primacy of the spoken over the written form; and the importance of the training of form or grammar. Applying…

  19. Formulaic Sequences and the Implications for Second Language Learning

    Science.gov (United States)

    Xu, Qi

    2016-01-01

    The present paper is a review of literature in relation to formulaic sequences and the implications for second language learning. The formulaic sequence is a significant part of our language, and plays an essential role in both first and second language learning. The paper first introduces the definition, classifications, and major features of…

  20. Gender and Leadership: The Implications of Small Group Research.

    Science.gov (United States)

    Gale, Linda Lyman

    1988-01-01

    Reviews selected literature from the small group communication research on gender and leadership emergence and suggests implications of this research for women seeking administrative positions. Hopes that, as men and women become sensitive to effects of sex-role stereotypes on group dynamics and leadership behaviors, there will be increase in…

  1. A Brief History of Leadership Preparation. Implications from UCEA

    Science.gov (United States)

    McCarthy, Martha M.; Forsyth, Patrick B.

    2010-01-01

    In 2009, the "Handbook of Research on the Education of School Leaders" was published by the University Council for Educational Administration (UCEA). The chapter discussed in this issue of "Implications," introduces a conceptual model for describing the different kinds of knowledge and the interactions among technical knowledge, artistry, and…

  2. Hydrodynamic processes in sharp meander bends and their morphological implications

    NARCIS (Netherlands)

    Blanckaert, K.

    2011-01-01

    The migration rate of sharp meander bends exhibits large variance and indicates that some sharply curved bends tend to stabilize. These observations remain unexplained. This paper examines three hydrodynamic processes in sharp bends with fixed banks and discusses their morphological implications: se

  3. The nano-plasma interface: implications of the protein corona

    OpenAIRE

    Wolfram, Joy; Yang, Yong; Shen, Jianliang; Moten, Asad; Chen, Chunying; Shen, Haifa; Ferrari, Mauro; Zhao, Yuliang

    2014-01-01

    The interactions between nanoparticles and macromolecules in the blood plasma dictate the biocompatibility and efficacy of nanotherapeutics. Accordingly, the properties of nanoparticles and endogenous biomolecules change at the nano-plasma interface. Here, we review the implications of such changes including toxicity, immunological recognition, molecular targeting, biodistribution, intracellular uptake, and drug release. Although this interface poses several challenges for nanomedicine, it al...

  4. LHCb results on flavour physics and implications to BSM

    International Nuclear Information System (INIS)

    LHCb is a dedicated flavour physics experiment at the LHC. Precision measurements of CP violation and the study of rare decays of hadrons containing beauty and charm quarks constitute powerful searches for New Physics. A selection of recent LHCb results and their implications to physics beyond the Standard Model are discussed.

  5. Causes and implications of colloid and microorganism retention hysteresis

    Science.gov (United States)

    Experiments were designed to better understand the causes and implications of colloid and microorganism retention hysteresis with transients in solution ionic strength (IS). Saturated packed column experiments were conducted using two sizes of carboxyl modified latex (CML) microspheres (0.1 and 1.1...

  6. English as a Lingua Franca: Concepts, Use, and Implications

    Science.gov (United States)

    Cogo, Alessia

    2012-01-01

    Sowden's article raises a number of questions concerning English as a Lingua Franca (ELF) and criticizes it as a simplified and culturally neutral means of communication. In this response, I address the issues concerning the conceptualization and use of ELF as well as the implications for ELT. I provide up-to-date evidence of ELF research and show…

  7. A Gaming Frame of Mind: Digital Contexts and Academic Implications

    Science.gov (United States)

    Abrams, Sandra S.

    2009-01-01

    When considering the interdisciplinary nature of education, researchers need to acknowledge students' traditional and multimodal literacies and learning environments. Technological changes have brought about new learning spaces and what students learn through their video gaming experiences seems to have important academic implications and…

  8. Mental Illness in Offender Populations: Prevalence, Duty and Implications

    Science.gov (United States)

    Soderstrom, Irina R.

    2007-01-01

    Prisons are increasingly being filled with inmates who suffer from mental illness. This paper examines the prevalence of mental illness in American jails and prisons, the duty government and society has to provide appropriate mental health treatment, and the implications for inmate safety, costs, recidivism, and community reintegration if…

  9. Heart failure: SGLT2 inhibitors and heart failure -- clinical implications.

    Science.gov (United States)

    Raz, Itamar; Cahn, Avivit

    2016-04-01

    The latest findings from the EMPA-REG OUTCOME trial show a 34% reduction in hospitalization for heart failure or cardiovascular death in patients receiving empagliflozin, a sodium/glucose cotransporter 2 (SGLT2) inhibitor, compared with placebo. These outstanding results call for discussion of the clinical implications, and in-depth studies of the mechanisms of action of SGLT2 inhibitors. PMID:26961066

  10. Sexual Objectification of Women: Clinical Implications and Training Considerations

    Science.gov (United States)

    Szymanski, Dawn M.; Carr, Erika R.; Moffitt, Lauren B.

    2011-01-01

    This article focuses on the implications of theory and empirical research on the sexual objectification of women. Drawing largely from the American Psychological Association's 2007 "Guidelines for Psychological Practice With Girls and Women," the 2007 "Report of the American Psychological Association's Task Force on the Sexualization of Girls,"…

  11. Implications of climate change for tourism in Australia

    NARCIS (Netherlands)

    Amelung, B.; Nicholls, S.

    2014-01-01

    This study assesses the impacts of projected climate change on Australia's tourism industry. Based on application of the Tourism Climatic Index, it investigates potential changes in climatic attractiveness for Australia's major destinations, and discusses implications for tourist flows and tourism p

  12. Suicide in Middle Level Schools: Implications for Principals.

    Science.gov (United States)

    Toepfer, Conrad F., Jr.

    1986-01-01

    Prevention of teenage suicide and coping with it when it occurs is an increasing concern for middle-level principals. This article focuses on specific implications of the youth suicide problem for middle-level principals with considerations for other principals as well. (Author/TE)

  13. Student Work Issues: Implications for College Transition and Retention.

    Science.gov (United States)

    Hey, William; Calderon, Kristine S.; Seabert, Denise

    2003-01-01

    Studied job stress of employed college students and considered the implications of this stress for college life and student retention. Findings for 275 college students at 2 universities show that for some students having a job adds more stress to their lives, increases exhaustion levels, and interferes with school responsibilities. (SLD)

  14. Drawing Inferences from Semantically Positive and Negative Implicative Predicates.

    Science.gov (United States)

    Vosniadou, Stella

    A study investigated the inferential processing involved in the comprehension of a class of complex predicates (such as "remember to,""manage to,""fail to," and "neglect to") that are known as implicative. The subjects, 64 college students, were timed while they drew inferences from syntactically affirmative and negative sentences containing the…

  15. Baccalaureate Degrees at Ontario Colleges: Issues and Implications

    Science.gov (United States)

    Panacci, Adam G.

    2014-01-01

    This paper identifies and examines major issues and implications of the proposal to substantially increase the number of applied baccalaureate degrees offered by Ontario's Colleges of Applied Arts and Technology, including increasing four-year applied degree offerings and introducing three-year applied degrees. Currently, provincial…

  16. On Dynamic Characteristics of Culture and its Implications

    Institute of Scientific and Technical Information of China (English)

    赵凌志

    2015-01-01

    This paper mainly discusses the dynamic characteristic of western culture and Chinese culture from the intercultural perspective.Then it puts forward some implications for English teaching,it indicates that English teachers should pay due attention to improve the students cultural awareness and their own cultural teaching ability,adjust teaching content to adapt them to cultural changes.

  17. Implications of learning analytics for serious game design

    NARCIS (Netherlands)

    Baalsrud Hauge, Jannicke; Fernández Manjón, Baltasar; Bellotti, Francesco; Fiucci, Giusy; Padrón-Nápoles, Carmen; Nadolski, Rob; Westera, Wim

    2014-01-01

    This paper addresses the implications of combining learning analytics and serious games for improving game quality, monitoring and assessment of player behavior, gaming performance, game progression, learning goals achievement, and user’s appreciation. We introduce two modes of serious games analyti

  18. Understanding Homophobic Behavior and Its Implications for Policy and Practice

    Science.gov (United States)

    Poteat, V. Paul; Russell, Stephen T.

    2013-01-01

    In this article, we consider recent advances in scholarship on homophobic bullying, and implications for policy and practice. We first consider toward whom homophobic behavior is directed, drawing attention to the nuances among LGBT youth, and the realities of homophobic bullying for heterosexual or straight youth. We review the correlates or…

  19. Social and Labour Implications of Flexible Manufacturing Systems.

    Science.gov (United States)

    Ebel, Karl-H.

    1985-01-01

    The flexible manufacturing system (FMS), a new way of organizing the production process by means of numerical control machines, robots, and computerized workstations, is described. The author examines some of the implications of FMS and the challenges it poses. (Author/CT)

  20. The Institutional Implications of the Unfair Terms Directive in Poland

    NARCIS (Netherlands)

    R. Mańko

    2009-01-01

    In this paper I focus on the institutional implications of the EU Unfair Terms Directive (93/13) in Poland in the broader context of the welfare state model prevalent in that post-socialist EU Member State. I depart from the assumption that there is, in principle, a link between the intensity of the

  1. Elasticity of fertilizer and its implication for subsidy

    OpenAIRE

    Jabbar, M. A.; Islam, Md. Shariful

    1981-01-01

    In order to address an on-going debate about the effect of price vs non-price factors on the demand and utilization of fertilizers and its implication for subsidy, this study used a sample farm level data to test the effect of price on demand.

  2. Somatosensory dysfunctin in fibromyaligia : Implications for pathophysiological mechanisms

    OpenAIRE

    Kosek, Eva

    1996-01-01

    SOMATOSENSORY DYSFUNCTION IN FIBROMYALGIA. IMPLICATIONS FOR PATHOPHYSIOLOGICAL MECHANISMS. Eva KosekDissertation from the Department of Rehabilitation Medicine, Karolinska Institure/Hospital, Stoclcholm, Sweden Fibromyalgia is a chronic pain syndrome characterized by generalized pain, tenderness,disturbed sleep and pronounced fatigue. The pathophysiology is unknown ...

  3. IMPLICATION OF MARKETING PLAN: FOR MARKETING LIBRARY AND INFORMATION SERVICES

    OpenAIRE

    V. A. NAIKWADI AND P. M. CHASKAR

    2012-01-01

    The paper describes the meaning and purpose of marketing in academic libraries and discusses five laws of library science in the view of marketing. It also describes marketing process, its development and implication of marketing plan, and list of the tools and techniques for marketing

  4. Health Implications of Smokeless Tobacco Use. Volume 6, Number 1.

    Science.gov (United States)

    National Institutes of Health (DHHS), Bethesda, MD. Office of Medical Applications of Research.

    Concerned with the increase in use of chewing tobacco and snuff, this brochure looks at the health risks of using smokeless tobacco. It presents five questions about smokeless tobacco use and provides answers to the questions developed by a consensus development conference on health implications of smokeless tobacco use convened by the National…

  5. Global Economies of Fear: Affect, Politics and Pedagogical Implications

    Science.gov (United States)

    Zembylas, Michalinos

    2009-01-01

    This article seeks to explore the importance of the affective politics of fear in education and to discuss the implications for educational policy, theory and practice. The aim is to explore how discourses of fear work in some educational contexts and draw significant boundaries between "us" and "them" through the structuring of curriculum and…

  6. Radiological protection, environmental implications, health and risk management: forum

    International Nuclear Information System (INIS)

    Topics related to the radioactivity or radiation are presented. The importance of protection and security measures that are required both for public health, occupational health and the medical radiation is analyzed. In addition, it emphasizes the risks faced by professionals who work with radioactivity. Issues that confront the serious environmental implications of such activities are also showed

  7. File-Sharing among College Students: Moral and Legal Implications

    Science.gov (United States)

    Cockrum, Colton Dwayne

    2010-01-01

    This study was designed to explore the phenomenon of college students who illegally file-share. The main research question was, "What are the experiences of college students who file-share and what are their perspectives on the moral and legal implications for doing so?" Data were collected from six students using interviews, focus groups, and…

  8. Psychological processes and paranoia: implications for forensic behavioural science.

    Science.gov (United States)

    Bentall, Richard P; Taylor, Jayne L

    2006-01-01

    Paranoid delusions have recently become the focus of empirical research. In this article, we review studies of the psychological mechanisms that might be involved in paranoid thinking and discuss their implications for forensic behaviour science. Paranoia has not been consistently associated with any specific neuropsychological abnormality. However, evidence supports three broad types of mechanism that might be involved in delusional thinking in general and paranoia in particular: anomalous perceptual experiences, abnormal reasoning, and motivational factors. There is some evidence that paranoia may be associated with hearing loss, and good evidence that paranoid patients attend excessively to threatening information. Although general reasoning ability seems to be unaffected, there is strong evidence that a jumping- to-conclusions style of reasoning about data is implicated in delusions in general, but less consistent evidence specifically linking paranoia to impaired theory of mind. Finally, there appears to be a strong association between paranoia and negative self-esteem, and some evidence that attempts to protect self-esteem by attributing negative events to external causes are implicated. Some of these processes have recently been implicated in violent behaviour, and they therefore have the potential to explain the apparent association between paranoid delusions and offending.

  9. Physical Education and Implications for Students with Asperger's Syndrome

    Science.gov (United States)

    Simpson, Cynthia G.; Gaus, Mark D.; Biggs, Mary Jo Garcia; Williams, James, Jr.

    2010-01-01

    In this article, James Williams, a young man with Asperger's syndrome (AS) shares his experiences taking physical education in a generalized education setting and discusses the implications for students with AS. He was diagnosed with AS when he was 9 years old. School was tough at times, especially when social interactions came into play. One of…

  10. Nutrition Advertisements in Consumer Magazines: Health Implications for African Americans.

    Science.gov (United States)

    Pratt, Charlotte A.; Pratt, Cornelius B.

    1996-01-01

    Examines the "Ladies' Home Journal" and two popular consumer magazines that target blacks to determine the proportions of food and beverage advertisements, nutrition advertisements and their promotional messages, and the health implications they reveal. Findings reveal these magazines had a significantly higher number of alcohol ads, limited…

  11. Local Citation Analysis of Graduate Biology Theses: Collection Development Implications

    Science.gov (United States)

    Miller, Laura Newton

    2011-01-01

    This paper will focus on the citation analysis of graduate masters theses from Carleton University's Biology Department with implications for library collection management decisions. Twenty-five masters theses were studied to determine citation types and percentages, ranking of journals by frequency of citation and by number of authors citing, and…

  12. Green certification and building performance: Implications for tangibles and intangibles

    NARCIS (Netherlands)

    Devine, A.; Kok, N.

    2015-01-01

    Commercial buildings represent a significant share of global energy consumption. In the general absence of regulation, voluntary labeling and green building certification schemes have been introduced to reflect this externality to building owners and tenants. The implications of such schemes have pr

  13. The interface of depression and cardiovascular disease: therapeutic implications.

    Science.gov (United States)

    Seligman, Fred; Nemeroff, Charles B

    2015-05-01

    Patients with major depression are at an increased risk for developing cardiovascular disease, respond more poorly to treatment, and exhibit worse outcomes, including increased morbidity and mortality. This article reviews the relationship between depression and heart disease, with an emphasis on epidemiology, biological substrates that likely underlie this relationship, and implications for treatment.

  14. Primary and Secondary Labor Markets: Implications for Vocational Rehabilitation.

    Science.gov (United States)

    Hagner, David

    2000-01-01

    Reviews theoretical and empirical work in labor economics and the sociology of work relating to the segmentation of the labor market into a primary and a secondary sector and examines the implications for vocational rehabilitation. Transition into primary sector employment is explored as an important aspect of career development for individuals…

  15. Winston Churchill's "Iron Curtain" Address: Implications for the Present.

    Science.gov (United States)

    Bush, George

    1988-01-01

    Evaluates the "Iron Curtain" speech made by Winston Churchill in 1946, discussing its relevance and implications for the present. Examines Churchill's predictions for the future and his assessment of the USSR. Reviews world developments since the speech and proposes foreign policy goals for the next 40 years. (GEA)

  16. Expectancy in Melody: Tests of the Implication-Realization Model.

    Science.gov (United States)

    Schellenberg, E. Glenn

    1996-01-01

    Three experiments examined implication-realization model's description of tone-to-tone expectancies for continuations of melodies. The model successfully predicted listeners' judgments across different musical styles, regardless of the listener's musical training or nationality. The collinearity of the model's predictors indicated, however, that a…

  17. Prototype Theory and Its Implication into English Vocabulary Teaching

    Institute of Scientific and Technical Information of China (English)

    郑禄娟; 张锐

    2015-01-01

    Prototype is the cognitive reference point that human beings use to categorize the world.It is the best and most typical member in the category while the other members of the category are centered on it.Guided by prototype theory,this paper will discuss some implications to English vocabulary teaching.

  18. Implications of a Contextualist Approach to Media-Effects Research.

    Science.gov (United States)

    Perry, David K.

    1988-01-01

    Discusses implications of the contextualism of William McGuire for media-effects research and for the answers media-effects researchers give to questions of social concern. Argues that mass communication research long has contained latent contextualist orientations. (MS)

  19. The Skills Implications of Electronic Retailing. IES Final Report.

    Science.gov (United States)

    Tackey, Nii Djan; Hillage, Jim; Jagger, Nick; Bates, Peter

    The skills and education/training implications of the development of electronic commerce in the United Kingdom's retail industry and its associated supply chain were examined. The major data collection activities were as follows: a literature review; consultation with leading academics and advisers; an e-mail-based call for information from…

  20. Responding to the double implication of telemarketers' opinion queries

    NARCIS (Netherlands)

    Mazeland, H

    2004-01-01

    During a call, telemarketers sometimes solicit respondent's opinions about a product or service. This turns out to be a query with multiple implications, and respondents are alive to them. On the one hand, the recipient orients to a local preference to evaluate the telemarketer's product positively.

  1. The implications of the Human Tissue Act 2004 for dentistry.

    Science.gov (United States)

    Forsyth, Laura; Woof, Marcus

    2006-12-23

    Partly as a consequence of the inquiries into the events at the Bristol Royal Infirmary and the Royal Liverpool Children's Hospital (Alder Hey), the Government recently enacted the Human Tissue Act 2004. The main provisions of the Act came into force on 1 September 2006 and have potential implications for dentists. PMID:17183410

  2. Guattari's Ecosophy and Implications for Pedagogy

    Science.gov (United States)

    Greenhalgh-Spencer, Heather

    2014-01-01

    Guattari's ecosophy has implications for many types of pedagogy practiced in the school. While Guattari never explicitly advocated the educational use of ecosophy, I explore in this article how it can be used as a lens to "read" pedagogy in nuanced ways, highlighting oppressive premises and practices. I first discuss Guattari's…

  3. Behavioral Momentum: Implications and Development from Reinforcement Theories.

    Science.gov (United States)

    Plaud, Joseph J.; Gaither, George A.

    1996-01-01

    Analyzes historical and contemporary theories of reinforcement and clinical application of reinforcement principles to behavior and modification therapy. Presents a behavioral momentum model that studies the allocation of behavior under changed environmental constraints and discusses the implications of this model on behavior modification and…

  4. Innovation and inter-firm linkages : new implications for policy

    NARCIS (Netherlands)

    Nooteboom, B

    1999-01-01

    This article discusses the implications for competition, innovation and learning of different forms of inter-firm linkage, ways to govern them, different 'generic systems' of innovation, and government policy. It employs a transformed theory of transactions that can deal with innovation and learning

  5. Are the insular cortex and cortisol implicated in Parkinsonian features?

    NARCIS (Netherlands)

    Tops, Mattie

    2006-01-01

    Recent studies implicate insular cortex and the hormone cortisol in Parkinsonian features. Dopaminergic alterations at the level of the insula may be involved in changes in personality (i.e. novelty seeking) and symptoms of hemispatial neglect. I discuss this evidence and suggest that attention in f

  6. The Religious Implications of an Historical Approach to Jewish Studies.

    Science.gov (United States)

    Furst, Rachel

    This project examines the religious implications of an approach to "limmudei kodesh" (primarily the study of Talmud) and "halakhah" (an integration of academic scholarship with traditional Torah study and the evaluation of the educational pros and cons of a curriculum built on such a synthesis). In the concerted effort over the past century to…

  7. Privacy implications of presence sharing in mobile messaging applications

    NARCIS (Netherlands)

    Buchenscheit, Andreas; Könings, Bastian; Neubert, Andreas; Schaub, Florian; Schneider, Matthias; Kargl, Frank

    2014-01-01

    Mobile messaging applications, such as WhatsApp, provide a free alternative for mobile texting on smartphones. Mobile messengers typically also share presence information about users to indicate when a user is online. We investigated the privacy implications of such presence updates, using WhatsApp

  8. Evaluating the social and cultural implications of the internet

    NARCIS (Netherlands)

    Brey, Philip

    2006-01-01

    Since the Internet's breakthrough as a mass medium, it has become a topic of discussion because of its implications for society. At one extreme, one finds those who only see great benefits and consider the Internet a tool for freedom, commerce, connectivity, and other societal benefits. At the other

  9. The Male Role in Contraception: Implications for Health Education.

    Science.gov (United States)

    Chng, Chwee Lye

    1983-01-01

    Many males still perceive contraception as a woman's responsibility. This paper describes male contraceptives and their effectiveness and draws implications for school and community health education professionals. More equitable sharing of the responsibility for contraception might result in more effective contraception. (PP)

  10. K-12 Implications Seen in Some Cases before High Court

    Science.gov (United States)

    Walsh, Mark

    2010-01-01

    Arizona's variation on government vouchers for religious schools and California's prohibition on the sale of violent video games to minors present the top two cases with implications for education in the U.S. Supreme Court term that formally begins Oct. 4. New Justice Elena Kagan brings to the court extensive education policy experience as a…

  11. The Inhibition of Pretend Play and Its Implications for Development.

    Science.gov (United States)

    Gordon, Debra E.

    1993-01-01

    Describes four kinds of pretend play inhibition observed in children from three to nine years of age. Proposes hypotheses regarding potential causes and developmental sequelae of pretend play difficulties, in both cognitive and socioaffective realms. Discusses the implications of children's pretend play inhibition for examining relationships…

  12. The Implication of Peer Feedback to College English Teaching

    Institute of Scientific and Technical Information of China (English)

    郝家荣; 张宏

    2009-01-01

    With the increasing number of college students enrollment, non - English major students have paid much attention to error correction and peer feedback on writing. This article sheds some light on the benefits and implication of peer feedback on college English teaching.

  13. New physics searches at the LHC: theory implications

    Energy Technology Data Exchange (ETDEWEB)

    Weiler, Andreas [DESY, Hamburg (Germany)

    2012-07-01

    I discuss the theoretical implications of the new physics searches at the LHC. The experimental program has been very successful and we have started to explore crucial regions of parameter space. I discuss what we have learned so far, which models might be getting into trouble and what the next frontiers are.

  14. The Risk Premium for Equity : Explanations and Implications

    NARCIS (Netherlands)

    Grant, S.; Quiggin, J.

    2001-01-01

    The equity premium puzzle shows that using standard parameters and setup, the Consumption-based Capital Asset Pricing Model's (CCAPM's) prediction of the premium associated with systematic risk is out by an order of magnitude.The object of this paper is to consider the implications of each of the br

  15. Understanding Students with Diabetes: Implications for the Physical Education Professional.

    Science.gov (United States)

    Petray, Clayre; And Others

    1997-01-01

    Provides physical educators with an understanding of diabetes, noting important considerations when teaching physical education to students with diabetes. Discusses four aspects of the issue (overview; common questions and answers concerning the control of diabetes; balancing insulin, food intake, and physical activity; and implications for…

  16. Implication of Information and Communication Technologies for the Internationalisation of Services

    DEFF Research Database (Denmark)

    Henten, Anders; Skouby, Knud Erik

    1997-01-01

    Paper on the implications of ICTs on the internationalisation of services - with an emphasis on factors affecting this development.......Paper on the implications of ICTs on the internationalisation of services - with an emphasis on factors affecting this development....

  17. 75 FR 76460 - Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for...

    Science.gov (United States)

    2010-12-08

    ... AGENCY Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for..., ``Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview and Implications for Risk Assessment.... ADDRESSES: The draft ``Lymphohematopoietic Cancers Induced by Chemicals and Other Agents: Overview...

  18. Resource efficiency and economic implications of alternatives to surgical castration without anaesthesia

    NARCIS (Netherlands)

    Roest, de K.; Montanari, C.; Fowler, T.; Baltussen, W.H.M.

    2009-01-01

    This paper presents an analysis of the economic implications of alternative methods to surgical castration without anaesthesia. Detailed research results on the economic implications of four different alternatives are reported. castration with local anaesthesia, castration with general anaesthesia,

  19. A ‘Brexit’ would have important implications at the European and international levels

    OpenAIRE

    Oliver, Tim

    2014-01-01

    The implications of a ‘Brexit’ for the UK has been endlessly discussed, but its implications for the EU and other international powers has hardly been considered. Tim Oliver explores the complex set of possibilities and implications at the European and international level that both the UK and EU need to keep in mind as they move forward.

  20. DMPD: Therapeutic implications of the TLR and VDR partnership. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 17276732 Therapeutic implications of the TLR and VDR partnership. Liu PT, Krutzik S...R, Modlin RL. Trends Mol Med. 2007 Mar;13(3):117-24. Epub 2007 Feb 5. (.png) (.svg) (.html) (.csml) Show Therapeutic implications... of the TLR and VDR partnership. PubmedID 17276732 Title Therapeutic implications of th

  1. Fuzzy controllers based on some fuzzy implication operators and their response functions

    Institute of Scientific and Technical Information of China (English)

    LI Hongxing; YOU Fei; PENG Jiayin

    2004-01-01

    The fuzzy controllers constructed by 23 fuzzy implication operators based on CRI algorithm and their response functions are discussed.The conclusions show that the fuzzy controllers constructed by 9 fuzzy implication operators are universal approximators to continuous functions and can be used in practical fuzzy control systems.And these 9 fuzzy implication operators except for Einstein operator intersection are all the adjoint pairs of some fuzzy implication operators.Besides, there are 3 other fuzzy controllers formed by fuzzy implication operators being regarded approximately as fitted functions.

  2. Bidirectional voltage biased implication operations using SiOx based unipolar memristors

    Science.gov (United States)

    Zhou, Fei; Guckert, Lauren; Chang, Yao-Feng; Swartzlander, Earl E.; Lee, Jack

    2015-11-01

    This work presents a material implication implementation using SiOx based unipolar memristors. SiOx memristors with TaN/SiOx/Si structures have been fabricated, characterized, and used in the implication operation. The implication function and its truth table were well implemented using both positive and negative voltages for load resistor bias. The voltage range for the implication operation is reduced due to bidirectional bias. The key factors for the operation of material implication, such as load resistance, characteristics of the memristor, and design tradeoffs were investigated. This work demonstrates that unipolar SiOx based memristors are suitable for logic operations.

  3. Some Implications for Regulation of ICT and Media Convergence

    DEFF Research Database (Denmark)

    Henten, Anders; Falch, Morten; Tadayoni, Reza

    The term convergence in the areas of ICT and media means the coming together of IT, telecommunications, broadcasting and other media, technologically, market and policy wise. It is the sectoral convergence of the hitherto more separate ICT and media areas, which is in focus, even though...... there certainly are also changes taking place vertically in the different sectors. The paper examines the relationships between technology and market developments and policy and regulatory initiatives. The issue is, therefore, not solely the implications of market and technology trends on policy and regulation......, but also the reverse implications of policy and regulatory frameworks on technology and market developments. The paper analyses the convergence tendencies at a technological, market level and policy and regulatory level. It is, however, the policy level, which is the centre of attention in the paper...

  4. Climate change and energy: The implications for the Spanish case

    International Nuclear Information System (INIS)

    This paper examines the mutual implications between the climate change problem and the actual energy-at-a-crossroads situation of the unsustainable world energy model. The implications for the Spanish case are studied as a case example. The paper provides a brief review of the scientific evidence on climate change, analyzes the causes of the present energy dilemma and characterizes the problem to be addressed. The principal challenge for the future climate regime is to identify the nature and level of commitment that will provide sufficient incentives for all countries, with such a diversity of interests. The paper also exposes the most plausible framework for the future climate regime, the basic components of such a regime, the role to be played by the major stake holders and some guidelines for future negotiations. (Author)

  5. Business development - the function, research propositions, and managerial implications

    DEFF Research Database (Denmark)

    Sørensen, Hans Eibe

      The management literature reflects remarkable little effort to investigate the nature and consequences of firms' business development activities. This exploratory research aims at synthesizing the scholarly knowledge on the subject with field interviews with senior business developers...... and executives from high-tech firms and venture capitalists in North America, Asia, and Europe to provide a foundation for future research. Business development is an emerging staff function providing an added level of sophistication to the firms' overall strategic management with interesting performance...... implications. The business development function is typically found in progressive firms especially within high-tech industries, but is argued to become critical for all types of firms across industries wishing to grow and accumulate wealth. Research propositions and managerial implications are discussed....

  6. New Developments in Mast Cell Biology: Clinical Implications.

    Science.gov (United States)

    Arthur, Greer; Bradding, Peter

    2016-09-01

    Mast cells (MCs) are present in connective tissue and at mucosal surfaces in all classes of vertebrates. In health, they contribute to tissue homeostasis, host defense, and tissue repair via multiple receptors regulating the release of a vast stockpile of proinflammatory mediators, proteases, and cytokines. However, these potentially protective cells are a double-edged sword. When there is a repeated or long-term stimulus, MC activation leads to tissue damage and dysfunction. Accordingly, MCs are implicated in the pathophysiologic aspects of numerous diseases covering all organs. Understanding the biology of MCs, their heterogeneity, mechanisms of activation, and signaling cascades may lead to the development of novel therapies for many diseases for which current treatments are lacking or are of poor efficacy. This review will focus on updates and developments in MC biology and their clinical implications, with a particular focus on their role in respiratory diseases.

  7. Global aging: implications for women and women's health.

    Science.gov (United States)

    Tabloski, Patricia A

    2004-01-01

    The world's older population has been growing for centuries; however, the pace of this growth is accelerating rapidly. According to the U.S. Census Bureau, by 2030, more than 60 countries will have 2 million or more older people. Population aging represents a "success story," with increasing numbers of people worldwide enjoying additional years of life. However, the sustained increase in numbers of older people (usually defined as persons over the age of 65) poses many challenges to policy makers and health care providers around the world. As the world population ages, we are just beginning to understand the social, economic, and political implications of the "age wave." The majority of older people are women, thus the implications of population changes for women and women's health are astounding. Nurses can take a national and world leadership role to adequately address the health care needs of increasing numbers of older women. PMID:15495709

  8. Genetics of Atrial Fibrillation and Possible Implications for Ischemic Stroke

    Directory of Open Access Journals (Sweden)

    Robin Lemmens

    2011-01-01

    Full Text Available Atrial fibrillation is the most common cardiac arrhythmia mainly caused by valvular, ischemic, hypertensive, and myopathic heart disease. Atrial fibrillation can occur in families suggesting a genetic background especially in younger subjects. Additionally recent studies have identified common genetic variants to be associated with atrial fibrillation in the general population. This cardiac arrhythmia has important public health implications because of its main complications: congestive heart failure and ischemic stroke. Since atrial fibrillation can result in ischemic stroke, one might assume that genetic determinants of this cardiac arrhythmia are also implicated in cerebrovascular disease. Ischemic stroke is a multifactorial, complex disease where multiple environmental and genetic factors interact. Whether genetic variants associated with a risk factor for ischemic stroke also increase the risk of a particular vascular endpoint still needs to be confirmed in many cases. Here we review the current knowledge on the genetic background of atrial fibrillation and the consequences for cerebrovascular disease.

  9. The Implications of the Upsurge of Female Criminality in Nigeria

    Directory of Open Access Journals (Sweden)

    Ameh, S. O.

    2013-08-01

    Full Text Available This work looks at the implications of the upsurge of female criminality in Nigeria. The work draws it strength from consulting numerous materials. It supports the assertion that more women are now involved in crime. The work infers that they have always been attracted to and actively involved in crime. Poverty, change in the traditional roles of women, the quest for economic occupations and unbiased criminal justice agents are identified as the main reasons for the increase in female criminality. The upsurge of female criminality is not without implications, as such, this study revealed that it will not only destroy the socialization structure of the society, it is a sure way to norm-less state. The need to discourage female criminality in Nigeria call for encouragement of women in the form of education and training, employment opportunities to reduce poverty and income disparities, and traditional leader as well as religious leaders involvement in the correctional process.

  10. Nursing informatics, ethics and decisions: implications for translational research

    DEFF Research Database (Denmark)

    Kaltoft, Mette Kjer; Nielsen, Jesper Bo; Dowie, Jack

    Nursing informatics, ethics and decisions: implications for translational research Objective: To introduce, in the multi-disciplinary contexts of clinical decision making and policy formation, a theory-based decision-analytic framework for the transparent forward translation of research......-calculation with evidence-based ratings for option performance on those criteria to produce a preference-sensitive assessment or opinion. Results: The first example shows the framework connecting nursing informatics and nursing ethics in the clinical context of a nurse’s decision to disclose or not disclose information......, satisfaction, Quality of Life), organization-related (staff and work environment, internal and external communication and relationships) and economics-related (start-up costs, financial implications and externalities)). Conclusion: Web-based decision support can provide nursing with a template, technique...

  11. Squark Flavor Implications from B --> K* l+ l-

    CERN Document Server

    Behring, Arnd; Hiller, Gudrun; Schacht, Stefan

    2012-01-01

    Recent experimental and theoretical progress regarding B --> K* l+ l- decays led to improved bounds on the Wilson coefficients C_9 and C_10 of four-fermion operators of the |Delta B|=|Delta S|=1 effective Hamiltonian. We analyze the resulting implications on squark flavor violation in the MSSM and obtain new constraints on flavor-changing left-right mixing in the up-squark-sector. We find the dimensionless flavor mixing parameter (delta^u_23)_LR, depending on the flavor-diagonal MSSM masses and couplings, to be as low as \\lesssim 0.1. This has implications for models based on radiative flavor violation and leads to BR(B_s --> mu+ mu-) \\gtrsim 1 x 10^-9. Rare top decays t --> c gamma, t --> c g, t --> c Z have branching ratios predicted to be below \\lesssim few times 10^-8, 10^-6 and 10^-7, respectively.

  12. ERP in large Danish enterprises: Implications for SCM

    DEFF Research Database (Denmark)

    Møller, Charles

    2004-01-01

    This paper argues that with the present state of Enterprise Resource Planning (ERP) adoption by the companies, the potential benefits of Supply Chain Management (SCM) and integration is about to be unleashed. This paper presents the results and the implications of a survey on ERP adoption...... in the 500 largest Danish enterprises. The study is based on telephone interviews with ERP managers in 88.4% of the "top 500" enterprises in Denmark. Based on the survey, the paper suggests the following four propositions: (i) ERP has become the pervasive infrastructure; (ii) ERP has become a contemporary...... technology; (iii) ERP adoption has matured; and (iv) ERP adoption is converging towards a dominant design. Finally, the paper discusses the general implications of the surveyed state of practice on the SCM research challenges. Consequently we argue that research needs to adjust its conceptions of the ERP...

  13. Implications of bilateral free trade agreements on access to medicines.

    Science.gov (United States)

    Correa, Carlos María

    2006-05-01

    The TRIPS Agreement of the World Trade Organization (WTO) mandated the introduction of protection of intellectual property rights, notably patents, for pharmaceutical products. While the implications for the access to medicines contained in the terms of this Agreement raised significant concerns, a recent new wave of free trade agreements, negotiated outside the WTO, requires even higher levels of intellectual property protection for medicines than those mandated by that Agreement. The measures involved include the extension of the patent term beyond 20 years; prohibition of use of test data on drug efficacy and safety for certain periods for the approval of generic products; the linkage between drug registration and patent protection; in some cases, limitations to the grounds for granting compulsory licences. This article reviews some of these measures that further limit the competition of generic products and discusses their possible implication for access to medicines. PMID:16710551

  14. Imaging of Brain Dopamine Pathways: Implications for Understanding Obesity

    OpenAIRE

    Wang, Gene-Jack; Volkow, Nora D.; Panayotis K Thanos; Fowler, Joanna S.

    2009-01-01

    Obesity is typically associated with abnormal eating behaviors. Brain imaging studies in humans implicate the involvement of dopamine (DA)-modulated circuits in pathologic eating behavior(s). Food cues increase striatal extracellular DA, providing evidence for the involvement of DA in the nonhedonic motivational properties of food. Food cues also increase metabolism in the orbitofrontal cortex indicating the association of this region with the motivation for food consumption. Similar to drug-...

  15. Alternative materials for crystalline silicon solar cells - Risks and implications

    OpenAIRE

    Kwapil, Wolfram

    2010-01-01

    This thesis considers the use of alternative silicon materials for photovoltaics – often termed “upgraded metallurgical grade” silicon – from different angles and evaluates the risks and implications for the wafer and solar cell properties at selected steps along the entire process chain.The properties of the alternative, upgraded metallurgical grade silicon materials analyzed in the course of this thesis were governed by the simultaneous presence of boron and phosphorus in high concentration...

  16. Suicide methods in Asia: Implications in suicide prevention

    OpenAIRE

    Yip, Paul S. F.; Kevin Chien-Chang Wu; Ying-Yeh Chen

    2012-01-01

    As the largest continent in the World, Asia accounts for about 60% of World suicides. Preventing suicide by restricting access to suicide methods is one of the few evidence-based suicide prevention strategies. However, there has been a lack of systematic exploration of suicide methods in Asian countries. To amend this shortage, the current review examines the leading suicide methods in different Asian countries, their trend, their age- and sex- specific characteristics, and their implications...

  17. Strategic issues in information technology international implications for decision makers

    CERN Document Server

    Schütte, Hellmut

    1988-01-01

    Strategic Issues in Information Technology: International Implications for Decision Makers presents the significant development of information technology in the output of components, computers, and communication equipment and systems. This book discusses the integration of information technology into factories and offices to increase productivity.Organized into six parts encompassing 12 chapters, this book begins with an overview of the advancement towards an automated interpretation communication system to achieve real international communication. This text then examines the main determining

  18. Astrocytic Ion Dynamics: Implications for Potassium Buffering and Liquid Flow

    OpenAIRE

    Halnes, Geir; Pettersen, Klas H.; Øyehaug, Leiv; Rognes, Marie E.; Langtangen, Hans Petter; Einevoll, Gaute T.

    2016-01-01

    We review modeling of astrocyte ion dynamics with a specific focus on the implications of so-called spatial potassium buffering, where excess potassium in the extracellular space (ECS) is transported away to prevent pathological neural spiking. The recently introduced Kirchoff-Nernst-Planck (KNP) scheme for modeling ion dynamics in astrocytes (and brain tissue in general) is outlined and used to study such spatial buffering. We next describe how the ion dynamics of astrocytes may regulate mic...

  19. Economic Implications of International Tourism on Turkish Economy

    OpenAIRE

    Akal, Mustafa

    2009-01-01

    This study outlines, with a review of earlier studies, the effects of international tourism by showing developments in tourism-related economic parameters and discusses the implications of such tourism on the economy of Turkey. It asks how far international tourism contributes to the economic growth and development of Turkey; how far the country fully values its tourism potential by varying the focus of tourism facilities beyond the sun-sea-sand type of tourism, in order to lead to developmen...

  20. Outward Foreign Direct Investment in Unionized Oligopoly: Some Welfare Implications

    OpenAIRE

    Junichiro Ishida; Noriaki Matsushima

    2005-01-01

    It is often argued, though mostly informally, that outward foreign direct investment (FDI) is a synonym for the export of employment and thus detrimental to the home economy. To see whether and under what conditions this intuition indeed holds true, we construct a model of unionized duopoly and examine welfare implications of outward FDI on the home country. It is found that the presence of domestic competition gives rise to effects which have critical bearings on social welfare. There are tw...

  1. Administrative policies in Estonia : the implication on the structural arrangement

    OpenAIRE

    1997-01-01

    ADMINISTRATIVE POLICIES IN ESTONIA. THE IMPLICATION ON STRUCTURAL ARRANGEMENT Estonia has undergone vast range of changes and reforms in the last ten year period. The thesis seeks to give an account on the processes that depict the governance problematique from the administrative policy perspective. The thesis takes a closer look on the relevant political events, the development of legislation, and the factual arrangement of top administrative system. The research emphasizes t...

  2. Multiple Intelligence and its Implication in Adult Education

    Institute of Scientific and Technical Information of China (English)

    李佩绮

    2008-01-01

    <正>Theory of multiple intelligence was developed by Dr.Howard Gardner.In the theory of multiple intelligence,Gardner proposed eight different intelligences to account for a broader range of human potential in children and adults.It has great influence on education theory and teaching practice. The paper introduces the frames of multiple intelligence and discusses its implication in adult education.

  3. The implications of electronic trading in financial markets

    OpenAIRE

    Bank for International Settlements

    2001-01-01

    Preface The Committee on the Global Financial System (CGFS), known until 1999 as the Euro-Currency Standing Committee, serves as a discussion forum for the central bank community on financial stability questions. The CGFS has frequently been asked to examine the potential implications of innovations in global financial market practices. Recent projects by CGFS working groups have concerned the functioning of international interbank markets, financial derivatives and the systemic consequences ...

  4. Nuclear and solar energy implications for homeland security

    OpenAIRE

    Thibeaux, Allen L.

    2008-01-01

    Approved for public release; distribution is unlimited In the eyes of many experts, the world is moving away from oil as a cheap energy source. As this future unfolds, the United States may perform a leading role as the planet's premier energy consumer. Solar and nuclear power provide possibilities for this future which represent the extremes in terms of energy supply. The question this thesis asks is: what are the security implications of a substantial shift in energy policy in either a s...

  5. Implications of Philosophy for Engineering and Engineering Technology Bachelors Programs

    OpenAIRE

    Dyrenfurth, Michael; Murphy, Mike; Grimson, William

    2009-01-01

    This paper raises the question: What is philosophy and then, after describing its branches and school, it extends the definitions to implications for the practice of engineering and engineering technology education. It folds the definitions against the work of engineering faculty. The latter was described as including curriculum development, teaching, mentoring/advising, research/scholarship, and engagement. Sample codes of ethics are shared for engineering technology students and professionals.

  6. Demand for Carbonated Soft Drinks: Implications for Obesity Policy

    OpenAIRE

    Rigoberto A. Lopez; Kristen L. Fantuzzi

    2012-01-01

    This article examines consumer choices of Carbonated Soft Drinks (CSDs) and their implications for obesity policy. Demand in relation to product and consumer heterogeneity is estimated via a random coefficients logit model (Berry et al., 1995) applied to quarterly scanner data for 26 brands in 20 US cities, involving 40000 consumers. Counterfactual experiments show that caloric taxes could be effective in decreasing caloric CSD consumption though having little impact on obesity incidence.

  7. Sepsis induced immunosuppression: Implications for secondary infections and complications

    OpenAIRE

    Krishna M Sundar; Mazen Sires

    2013-01-01

    Sepsis is the commonest cause of admission to medical ICUs across the world. Mortality from sepsis continues to be high. Besides shock and multi-organ dysfunction occurring following the intense inflammatory reaction to sepsis, complications arising from sepsis-related immunoparalysis contribute to the morbidity and mortality from sepsis. This review explores the basis for sepsis related immune dysfunction and discusses its clinical implications for the treating intensivist. Recent trends ind...

  8. Histone deacetylase inhibitors: clinical implications for hematological malignancies

    OpenAIRE

    Tambaro, Francesco Paolo; Dell’Aversana, Carmela; Carafa, Vincenzo; Nebbioso, Angela; Radic, Branka; Ferrara, Felicetto; Altucci, Lucia

    2010-01-01

    Histone modifications have widely been implicated in cancer development and progression and are potentially reversible by drug treatments. The N-terminal tails of each histone extend outward through the DNA strand containing amino acid residues modified by posttranslational acetylation, methylation, and phosphorylation. These modifications change the secondary structure of the histone protein tails in relation to the DNA strands, increasing the distance between DNA and histones, and thus allo...

  9. China in 2005 Revisited: The Implications of International Capital Mobility

    OpenAIRE

    Ianchovichina, Elena; McDougall, Robert; Hertel, Thomas

    2000-01-01

    This paper revisits the analysis of the implications of China's economic growth on her trading partners presented in Arndt et al. (1997) using a dynamic, applied general equilibrium model that features international capital mobility. We find that accounting for the impact of China's growth on international capital markets reverses some of the findings in the paper by Arndt et al. In particular, net creditor regions lose while net debtor regions benefit from an economic slowdown in China du...

  10. Breast cancer screening in British Columbia: implications of diagnostic trajectories

    OpenAIRE

    McKay, Rachel

    2008-01-01

    Despite reductions in mortality rates, breast cancer remains the most common cancer and the second most common cause of cancer death in Canadian women. Organized screening programs have contributed to the decrease in breast cancer mortality by allowing for early diagnosis and treatment. The diagnostic phase following an abnormal screen has implications for patient well-being, clinical practice, and resource management in health care. We present data from British Columbia that show that improv...

  11. Ore concentrate line efficient operation: some energy saving implications

    Energy Technology Data Exchange (ETDEWEB)

    Ihle, Christian F. [BRASS Engineering Chile S.A., Santiago (Chile)

    2009-07-01

    Among the outstanding attributes slurry pipelines must have is the need to optimize production efficiency and, in particular, minimize energy consumption. In the present paper, the energy saving implications of three different factors, namely process variable uncertainties, transport control variables and pipeline availability are referred to and exemplified using an idealized Bingham-type slurry pipeline. Present examples suggest that important energy savings can be achieved with proper designs, equipment and operations scheduling. (author)

  12. Dopamine in Socioecological and Evolutionary Perspectives: Implications for Psychiatric Disorders

    OpenAIRE

    Yoshie eYamaguchi; Young-A eLee; Yukiori eGoto

    2015-01-01

    Dopamine (DA) transmission in brain areas such as the prefrontal cortex (PFC) and nucleus accumbens (NAcc) plays important roles in cognitive and affective function. As such, DA deficits have been implicated in a number of psychiatric disorders such as schizophrenia and attention deficit/hyperactivity disorder (ADHD). Accumulating evidence suggests that DA is also involved in social behavior of animals and humans. Although most animals organize and live in social groups, how the DA system f...

  13. Dopamine in socioecological and evolutionary perspectives: implications for psychiatric disorders

    OpenAIRE

    Yamaguchi, Yoshie; Lee, Young-A; Goto, Yukiori

    2015-01-01

    Dopamine (DA) transmission in brain areas such as the prefrontal cortex (PFC) and nucleus accumbens (NAcc) plays important roles in cognitive and affective function. As such, DA deficits have been implicated in a number of psychiatric disorders such as schizophrenia and attention deficit/hyperactivity disorder (ADHD). Accumulating evidence suggests that DA is also involved in social behavior of animals and humans. Although most animals organize and live in social groups, how the DA system fun...

  14. Social Implications of Fiscal Policy Responses During Crises

    OpenAIRE

    Carlos A. Vegh; Guillermo Vuletin

    2014-01-01

    This paper studies the social implications of fiscal policy responses to crises in Latin America over the last 40 years and in the Eurozone during the aftermath of the global financial crisis. We focus on the behavior of four social indicators: the poverty rate, income inequality, unemployment rate, and domestic conflict. We find a causal link from counteryclical (procyclical) fiscal policy responses to reductions (increases) in all four social indicators. These results call into question rec...

  15. Implications of SCUBA observations for the Planck Surveyor

    OpenAIRE

    Scott, Douglas; White, Martin

    1998-01-01

    We investigate the implications for the Planck Surveyor of the recent sub-millimetre number counts obtained using the SCUBA camera. Since it observes at the same frequency as one of the higher frequency science channels on Planck, SCUBA can provide constraints on the point-source contribution to the CMB angular power spectrum, which require no extrapolation in frequency. We have calculated the two-point function of these sub-millimetre sources, using a Poisson model normalized to the observed...

  16. Policy Preference Functions: The Implications of Recent Developments

    OpenAIRE

    Cramon-Taubadel, Stephan von

    1997-01-01

    The policy preference function (PPF) approach continues to be the subject of considerable interest in agricultural economics. Recent work has added sophistication and strengthened the approach's theoretical underpinnings. In this paper, several implications of this recent work are considered. First, the distinction between the PPF and the surplus transformation curve (STC) is stressed. Estimated PPF weights are derived from what we know about the STC. We actually know very little about the PP...

  17. Implications of the New Political Realities on Healthcare Reform

    OpenAIRE

    2010-01-01

    With the recent change in power in the US House of Representatives that will take effect in January, questions arise regarding potential modifications to some features in the healthcare reform bill and its implementation. With many provisions scheduled to take effect between 2011 and 2014, the political implications of the elections have an immediate practical relevance to health plans, employers, and other healthcare stakeholders. American Health & Drug Benefits discussed some of these issue...

  18. Implications of Indian Supreme Court's Innovations for Environmental Jurisprudence

    OpenAIRE

    Geetanjoy Sahu

    2008-01-01

    This paper analyses the implications of innovative methods of the Indian Supreme Court for environmental jurisprudence to protect and improve the environment. Innovative methods are understood in terms of application and creation of new principle and structure for environmental jurisprudence. Through a series of innovative methods the Supreme Court of India has not only ensured fundamental right of citizen to healthy environment but also has contributed immensely to the evolution of new princ...

  19. Child Mortality and Injury in Asia: Policy and programme implications

    OpenAIRE

    Michael (et al.) Linnan

    2007-01-01

    Special Series on Child Injury no.4 This paper presents a summary of the findings of the national and sub-national surveys and discusses the implications of the results on child health policy and programmes.The principal finding is that injury has generally been unrecognized as a leading cause of child death. This is largely because the previous estimates of child mortality causality were unable to include injury due to technical issues. The surveys provide convincing evidence that injury is ...

  20. Advances in Seabed Liquefaction and its Implications for Marine Structures

    DEFF Research Database (Denmark)

    Sumer, B. Mutlu

    2013-01-01

    A review is presented of recent advances in seabed liquefaction and its implications for marine structures. The review is organized in seven sections: Residual liquefaction, including the sequence of liquefaction, mathematical modelling, centrifuge modelling and comparison with standard wave......-flume results; Momentary liquefaction; Floatation of buried pipelines; Sinking of pipelines and marine objects; Liquefaction at gravity structures; Stability of rock berms in liquefied soils; and Impact of seismic-induced liquefaction....

  1. Multiple Intelligence Theory and Its Implications for Language Teaching

    Institute of Scientific and Technical Information of China (English)

    刘晓荣

    2014-01-01

    The theory of Multiple Intelligence plays an important guidance role in language teaching nowadays. Multiple Intelligence theory points out that human beings’ intelligence is multiple. Apart from the usual two forms of linguistics and logical-mathematical abilities, it consists of spatial, musical intelligence and so on. This paper focuses on Multiple Intelligence theory’s implications for language teaching and the use of teaching strategies designed on the basis of Multiple Intelligence theory.

  2. Genetics of Atrial Fibrillation and Possible Implications for Ischemic Stroke

    OpenAIRE

    Vincent Thijs; Robin Lemmens; Dieter Nuyens; Sylvia Hermans

    2011-01-01

    Atrial fibrillation is the most common cardiac arrhythmia mainly caused by valvular, ischemic, hypertensive, and myopathic heart disease. Atrial fibrillation can occur in families suggesting a genetic background especially in younger subjects. Additionally recent studies have identified common genetic variants to be associated with atrial fibrillation in the general population. This cardiac arrhythmia has important public health implications because of its main complications: congestive heart...

  3. Eating disordered patients: personality, alexithymia, and implications for primary care.

    OpenAIRE

    Beales, D. L.; Dolton, R

    2000-01-01

    BACKGROUND: Eating disorders are becoming more apparent in primary care. Descriptions of character traits related to people with eating disorders are rarely reported in the primary care literature and there is little awareness of the implications of alexithymia--a concept that defines the inability to identify or express emotion. We hypothesised that many individuals with active eating disorders have alexithymic traits and a tendency to somatize their distress. AIM: To analyse the character t...

  4. Commonality in hedge fund returns: driving factors and implications

    OpenAIRE

    Bussiere, M.; Hoerova, M.; Klaus, B.

    2014-01-01

    We measure the commonality in hedge fund returns, identify its main driving factor and analyse its implications for financial stability. We find that hedge funds’ commonality increased significantly from 2003 until 2006. We attribute this rise mainly to the increase in hedge funds’ exposure to emerging market equities, which we identify as a common factor in hedge fund returns over this period. Our results show that funds with a high commonality were affected disproportionately by illiquidity...

  5. Rethinking Development as Knowledge: Implications for Human Development

    OpenAIRE

    Mukherjee Reed, Ananya

    2000-01-01

    The idea that knowledge is critical for development is neither new nor controversial, yet its full implications cannot be assessed unless we clarify at least two sets of issues: (a) how exactly knowledge is conceptualised or, what constitutes knowledge; and (b) the conditions under which such knowledge is produced, evaluated and ‘exchanged' or ‘transferred'. This paper will attempt to provide some tentative answers to these two questions, with the ultimate objective of identifying the conditi...

  6. Diversification strategy and performance: implications for health services research.

    Science.gov (United States)

    Rivers, P A; Glover, S H; Munchus, G

    1999-01-01

    Health care represents a promising area of research due to its uniqueness. In recent years, considerable progress has been made in diversification strategy and performance research but not the study of health services strategy research. This article reviews diversification strategy and performance in health services domains. Adopting Datta, Rajagopalan, and Rasheed's (1991) framework, the authors evaluate the theoretical and empirical contributions of this research. The limitations and theoretical implications of these efforts are also explored.

  7. The nano-plasma interface: Implications of the protein corona.

    Science.gov (United States)

    Wolfram, Joy; Yang, Yong; Shen, Jianliang; Moten, Asad; Chen, Chunying; Shen, Haifa; Ferrari, Mauro; Zhao, Yuliang

    2014-12-01

    The interactions between nanoparticles and macromolecules in the blood plasma dictate the biocompatibility and efficacy of nanotherapeutics. Accordingly, the properties of nanoparticles and endogenous biomolecules change at the nano-plasma interface. Here, we review the implications of such changes including toxicity, immunological recognition, molecular targeting, biodistribution, intracellular uptake, and drug release. Although this interface poses several challenges for nanomedicine, it also presents opportunities for exploiting nanoparticle-protein interactions. PMID:24656615

  8. Cosmological implications of modified gravity induced by quantum metric fluctuations

    OpenAIRE

    Liu, Xing; Harko, Tiberiu; Liang, Shi-Dong

    2016-01-01

    We investigate the cosmological implications of modified gravities induced by the quantum fluctuations of the gravitational metric. If the metric can be decomposed as the sum of the classical and of a fluctuating part, of quantum origin, then the corresponding Einstein quantum gravity generates at the classical level modified gravity models with a nonminimal coupling between geometry and matter. As a first step in our study, after assuming that the expectation value of the quantum correction ...

  9. Homers regulate drug-induced neuroplasticity: Implications for addiction

    OpenAIRE

    Szumlinski, Karen K; Ary, Alexis W.; Lominac, Kevin D

    2007-01-01

    Drug addiction is a chronic, relapsing disorder, characterized by an uncontrollable motivation to seek and use drugs. Converging clinical and preclinical observations implicate pathologies within the corticolimbic glutamate system in the genetic predisposition to, and the development of, an addicted phenotype. Such observations pose cellular factors regulating glutamate transmission as likely molecular candidates in the etiology of addiction. Members of the Homer family of proteins regulate s...

  10. Pharmacometabolomics Reveals That Serotonin Is Implicated in Aspirin Response Variability

    OpenAIRE

    Ellero-Simatos, S; Lewis, JP; Georgiades, A; Yerges-Armstrong, LM; Beitelshees, AL; Horenstein, RB; Dane, A.; Harms, AC; Ramaker, R; Vreeken, RJ; Perry, CG; Zhu, H.; Sanchez, CL; Kühn, C.; ORTEL, TL

    2014-01-01

    While aspirin is generally effective for prevention of cardiovascular disease, considerable variation in drug response exists, resulting in some individuals displaying high on-treatment platelet reactivity. We used pharmacometabolomics to define pathways implicated in variation of response to treatment. We profiled serum samples from healthy subjects pre- and postaspirin (14 days, 81 mg/day) using mass spectrometry. We established a strong signature of aspirin exposure independent ...

  11. Disrupted caring attachments: implications for long-term care.

    Science.gov (United States)

    Flannery, Raymond B

    2002-01-01

    Caring attachments or social supports are the positive psychological and physical contacts and relationships between people. These attachments have been associated with improved health, well-being, and longevity. It is also true that disrupted caring attachments are associated with impaired health and well-being. This paper reviews the general medical and elder medical findings of disrupted caring attachments and negative health outcomes. The implications of these findings for dementia sufferers, caregivers, and long-term care staff are examined.

  12. Nursing informatics, ethics and decisions: implications for translational research

    OpenAIRE

    Kaltoft, Mette Kjer; Nielsen, Jesper Bo; Dowie, Jack

    2014-01-01

    Nursing informatics, ethics and decisions: implications for translational research Objective: To introduce, in the multi-disciplinary contexts of clinical decision making and policy formation, a theory-based decision-analytic framework for the transparent forward translation of research into practice which can simultaneously identify and communicate the needs for backward translation from practice to research.Method:Web-based decision analytic software is used to demonstrate how the weights f...

  13. Implications of WTO Accession for Selected Domestic Industries of Laos

    OpenAIRE

    Lord, Montague J.

    2010-01-01

    The study examines the implications of Lao PDR’s WTO accessions on the domestic cement, steel bar and brewery industries with a view to developing recommendations on how to concurrently manage the Government’s domestic strategic objectives with the country’s effective involvement in the global economy. Calculations of total protection (TE) to the industries shows that beer receives the highest level of protection (110%), followed by steel bars (17%) and cement (16%). The actual level of effec...

  14. Macroeconomic implications of virtual shopping : a theoretical approach

    OpenAIRE

    Yetkiner, I. Hakan; Horvath, Csilla

    2000-01-01

    Recently, parallel to developments in the communication technology, online shopping has become increasingly popular for many products, like books, CDs, software, and computers. Most analysts conjecture that the future will witness a wider basket of products and a higher trade volume via the Internet. This paper investigates the economic implications of Internet shopping in a Ricardian equilibrium framework. First, it shows the necessary and sufficient condition for the shift to Internet shopp...

  15. Nanotechnology Foresight: How Can We Explore Employment and Skills Implications?

    OpenAIRE

    Ian Miles

    2010-01-01

    Policymakers responsible for improving the skill base needed for future economic development must assess the implications of radical technological change in the future. The example selected here is in nanoscience and nanotechnology. The objective of this paper is to demonstrate the importance of using more than one scenario of long term development when assessing such a complex issue as technology development and the demand for skills. Scenario forecasting is appropriately based on assessing ...

  16. Conjecture on the physical implications of the scale anomaly

    Energy Technology Data Exchange (ETDEWEB)

    Hill, Christopher T.; /Fermilab

    2005-10-01

    Murray Gell-Mann, after co-inventing QCD, recognized the interplay of the scale anomaly, the renormalization group, and the origin of the strong scale, {Lambda}{sub QCD}. I tell a story, then elaborate this concept, and for the sake of discussion, propose a conjecture that the physical world is scale invariant in the classical, {h_bar}, limit. This principle has implications for the dimensionality of space-time, the cosmological constant, the weak scale, and Planck scale.

  17. Obesity Trends, Determinants and Policy Implications in Indonesia

    OpenAIRE

    Roemling, Cornelia; Qaim, Matin

    2012-01-01

    Obesity is becoming a serious issue in many developing countries, with negative implications for economic growth and human wellbeing. While previous micro level studies on obesity have mostly used cross-section data, we analyze trends and determinants with panel data from Indonesia. Over the past 20 years, obesity has increased remarkably in Indonesia across all population groups, including rural and low income strata. The problem is particularly severe among women. Panel regressions confirm ...

  18. The Economic Implications of Money Laundering in Nigeria

    OpenAIRE

    Uyoyou Kingsley Ogbodo; Ebipanipre Gabriel Mieseigha

    2013-01-01

    The effect of money laundering in frustrating legitimate business, and in corrupting the financial and socio political system should not be taken for granted. It is against this backdrop that this study seeks to examine the economic implication of money laundering in Nigeria. The accidental sampling method was used in the selection of 635 persons out of which 624 representing 98.27% of the sampled persons completely filled and returned the questionnaires administered to them. Data collected w...

  19. Structure and Mechanistic Implications of a Tryptophan Synthase Quinonoid Intermediate

    Energy Technology Data Exchange (ETDEWEB)

    Barends,T.; Domratcheva, T.; Kulik, V.; Blumenstein, L.; Niks, D.; Dunn, M.; Schlichting, I.

    2008-01-01

    Quinonoid intermediates play a key role in the catalytic mechanism of pyridoxal 5'-phosphate (PLP)-dependent enzymes. Whereas structures of other PLP-bound reaction intermediates have been determined, a high-quality structure of a quinonoid species has not been reported. We present the crystal structure of the indoline quinonoid intermediate of tryptophan synthase (see figure) and discuss its implications for the enzymatic mechanism and allosteric regulation.

  20. Earthquake 2005: Some Implications for Environment and Human Capital

    OpenAIRE

    Hamdani, Nisar Hussain; Shah, Syed Akhter Hussain

    2005-01-01

    Loss of human capital in the form of skills and experiences is one of the outcomes of any natural hazard such as earthquake, drought, famine, and floods. Generally such losses have many implications for further growth of individuals, communities and nations. Disaster management and risk assessment has established a new need to constitute a paradigm of planning frameworks to develop modules for dealing with interactive rehabilitation and reconstruction activities. However, such management stil...

  1. Evolution in invasive plants: implications for biological control

    OpenAIRE

    Müller-Schärer, Heinz; Schaffner, Urs; Steinger, Thomas

    2005-01-01

    Evidence is increasing that invasive plants can undergo rapid adaptive evolution during the process of range expansion. Here, we argue that evolutionary change during invasions will also affect plant–antagonist inter-actions and, thus, will have important implications for biological control programmes targeted at invasive plants. We explore how altered selection in the new range might influence the evolution of plant defence (resistance and tolerance) and life history. The degree to which suc...

  2. Implications of Decision Making Research for Decision Support and Displays

    OpenAIRE

    Morrison, Jeffrey G.; Kelly, Richard T.; Moore, Ronald A.; Hutchins, Susan G.

    1998-01-01

    To appear in J. A. Cannon-Bowers & E. Salas (Eds.), Decision Making Under Stress: Implications for Training and Simulation. A prototype decision support system (DSS) was developed to enhance Navy tactical decision making based on naturalistic decision processes. Displays were developed to support critical decision making tasks through recognition-primed and explanation-based reasoning processes, and cognitive analysis was conducted of the decision making problems faced by Navy ...

  3. Alterations in polyadenylation and its implications for endocrine disease

    DEFF Research Database (Denmark)

    Rehfeld, Anders Aagaard; Plass, Mireya; Krogh, Anders;

    2013-01-01

    , polyendocrinopathy, enteropathy, X-linked) and to be associated with type I and II diabetes, pre-eclampsia, fragile X-associated premature ovarian insufficiency, ectopic Cushing syndrome, and many cancer diseases, including several types of endocrine tumor diseases. Perspectives: Recent developments in high...... of alterations in polyadenylation in endocrine disease, an overview of the current literature on polyadenylation and summarizes the clinical implications of the current state of research in this field....

  4. Policy Implications of Limiting Immigrant Concentration in Danish Public Schools

    DEFF Research Database (Denmark)

    Andersen, Simon Calmar; Thomsen, Mette Kjærgaard

    2011-01-01

    since it is more feasible to change student composition in schools than the socioeconomic status of the individual students.This article describes theoretically the circumstances under which total student achievement can be increased by reallocating certain groups of students. Empirical analyses......’ educational outcome, by limiting the share of immigrant students at grade level at any one school to less than 50 percent. The policy implications of this finding are discussed....

  5. Considering Co-Players : Implications for research and design

    OpenAIRE

    Eklund, Lina

    2015-01-01

    This empirical study explores the role of co-players in players’ motivations and experiences of gaming through relational sociological analyses of interview and survey data. The aim is to bring attention to the importance of divergent gaming partners, and to offer some implications for considering co-players in game research and design. Results explore three gaming situations: playing with family members, playing with friends and playing with strangers, and shows how differently these co-play...

  6. Natural orifice transluminal endoscopic surgery (NOTES): implications for anesthesia.

    Science.gov (United States)

    Schaefer, Michael

    2009-01-01

    Natural orifice transluminal endoscopic surgery (NOTES) has recently evolved as a novel approach for abdominal surgery with great potential to further improve the advantages of laparoscopy over laparotomy. The first patients undergoing NOTES cholecystectomy or appendectomy reported no or only minimal pain, required no narcotic analgesics, and were discharged early from the hospital and immediately resumed daily activities. If this is confirmed by randomized controlled clinical trials, what are the potential implications for anesthesia? PMID:20948698

  7. Implications of purely classical gravity for inflationary tensor modes

    CERN Document Server

    Ashoorioon, Amjad; Mazumdar, Anupam

    2012-01-01

    We discuss the implications of purely classical, instead of quantum, theory of gravity for the gravitational wave spectrum generated during inflation. We show that a positive detection of primordial gravitational waves will no longer suffice to determine the scale of inflation in this case -- even a high-scale model of inflation can bypass the observational constraints due to large uncertainties in the initial classical amplitude of the tensor modes.

  8. Neutrino masses from SUSY: Different contributions and their implications

    Indian Academy of Sciences (India)

    Sudhir K Vempati

    2000-01-01

    We discuss the various sources of neutrino masses in supersymmetric standard models with explicit lepton number violation. We show that the bilinear lepton number violating soft terms in models with either bilinear or trilinear lepton number violating couplings in the superpotential, play an important role in determining the neutrino mass spectrum. A comparative study of the neutrino mass spectrum and its implications for the present neutrino anomalies in these models is presented.

  9. Pure versus hybrid: performance implications of Porter's generic strategies.

    Science.gov (United States)

    Kumar, K; Subramanian, R; Yauger, C

    1997-01-01

    This article identifies the strategic types in the hospital industry based on the hospital's use of Porter's generic strategies in their pure and hybrid forms. The article also examines differences in performance of hospitals across strategic types. Results indicate that hospitals that follow a focussed cost leadership strategy, in general, have superior performance on a variety of performance measures, while hospitals that use a combination of cost leadership and differentiation perform the poorest. Implications of findings for hospital administrators are also discussed.

  10. Water Implications of Large-Scale Land Acquisitions in Ghana

    OpenAIRE

    Timothy Olalekan Williams; Benjamin Gyampoh; Fred Kizito; Regassa Namara

    2012-01-01

    This paper examines the water dimensions of recent large-scale land acquisitions for biofuel production in the Ashanti, Brong-Ahafo and Northern regions of Ghana. Using secondary sources of data complemented by individual and group interviews, the paper reveals an almost universal lack of consideration of the implications of large-scale land deals for crop water requirements, the ecological functions of freshwater ecosystems and water rights of local smallholder farmers and other users. It do...

  11. The implications of migration theory for distributive justice

    OpenAIRE

    Sager, Alex

    2012-01-01

    This paper explores the implications of empirical theories of migration for normative accounts of migration and distributive justice. It examines neo-classical economics, world-systems theory, dual labor market theory, and feminist approaches to migration and contends that neo-classical economic theory in isolation provides an inadequate understanding of migration. Other theories provide a fuller account of how national and global economic, political, and social institutions cause and shape m...

  12. Foreign national prisoners in the UK: explanations and implications

    OpenAIRE

    Banks, James

    2011-01-01

    This article examines the rapid expansion of the foreign national prison population in the UK against a backdrop of public and political anxiety about immigration and crime. It explores official data considering some of the possible explanations for the growth in the number of foreign national prisoners and the implications this has for penal management. Whilst increases in both the number of foreign nationals entering the UK and the number of foreign nationals in UK prisons has strengthened ...

  13. The Hole Argument and Some Physical and Philosophical Implications

    OpenAIRE

    John Stachel

    2014-01-01

    This is a historical-critical study of the hole argument, concentrating on the interface between historical, philosophical and physical issues. Although it includes a review of its history, its primary aim is a discussion of the contemporary implications of the hole argument for physical theories based on dynamical, background-independent space-time structures. The historical review includes Einstein’s formulations of the hole argument, Kretschmann’s critique, as well as Hilbert’s reformu...

  14. Cesarean Section in Morbidly Obese Parturients: Practical Implications and Complications

    OpenAIRE

    Lovina SM Machado

    2012-01-01

    The prevalence of obesity has reached pandemic proportions across nations. Morbid obesity has a dramatic impact on pregnancy outcome. Cesarean section in these women poses many surgical, anesthetic, and logistical challenges. In view of the increased risk of cesarean delivery in morbidly obese women, the practical implications and complications are reviewed in this article. A Medline search was conducted to review the recent relevant articles in english literature on cesarean section in morbi...

  15. Implications of HIV PrEP Trials Results

    OpenAIRE

    Veronese, Fulvia; Anton, Peter; Fletcher, Courtney V.; DeGruttola, Victor; McGowan, Ian; Becker, Stephen; Zwerski, Sheryl; Burns, David

    2011-01-01

    Six randomized clinical trials have been implemented to examine the efficacy of tenofovir disoproxil fumarate (TDF) and/or TDF/emtricitabine (TDF/FTC) as preexposure prophylaxis for HIV-1 infection (PrEP). Although largely complementary, the six trials have many similar features. As the earliest results become available, an urgent question may arise regarding whether changes should be made in the conduct of the other trials. To consider this in advance, a Consultation on the Implications of H...

  16. An implication of G\\"odel's incompleteness theorem

    OpenAIRE

    Kitada, Hitoshi

    2009-01-01

    A proof of G\\"odel's incompleteness theorem is given. With this new proof a transfinite extension of G\\"odel's theorem is considered. It is shown that if one assumes the set theory ZFC on the meta level as well as on the object level, a contradiction arises. The cause is shown to be the implicit identification of the meta level and the object level hidden behind the G\\"odel numbering. An implication of these considerations is stated.

  17. Exploring Writing In The Workplace: Implications For Human Resource Development

    OpenAIRE

    AKDERE, Dr.Mesut; AZEVEDO, Dr.Ross E.

    2010-01-01

    Writing in the workplace is among the understudied business topics in the field of HRD. Yet, the impacts of writing in today's workplace are significant, and organizations making it a priority benefit from it. Furthermore, writing is related to the issue of workplace literacy which is the umbrella term for basic communication skills. This literature review provides a general view on workplace writing and discusses implications to HRD within a model research proposal

  18. Who nominates the board? - Implications on board diversity and turnover

    OpenAIRE

    Viskari, Milla

    2014-01-01

    This thesis assesses whether the type of nomination poses implications on board diversity in terms of age, gender, nationality and education, as well as turnover on a Finnish and Swedish data. The existing research on director selection and especially nomination committees is rather limited, and thus the research aims at contributing to the topic. The reviewed time period concerns 2008 to 2012, and altogether 55 Finnish and 55 Swedish public companies are included in the study, thus resul...

  19. Income Distribution Implications of Globalization and Liberalization in Africa

    OpenAIRE

    Kanbur, Ravi

    1999-01-01

    This paper surveys the main income distribution implications of greater openness in the African context. It considers trade, capital flows, technology, risk, and the ethnic dimension. It argues that the central policy dilemma for African policy makers is how to take advantage ofthe undoubted opportunities that integration into the world economy affords for rapid growth, while managing the attendant risks for domestic income distribution in its different dimensions. It proposes a research and ...

  20. Prenatal Psychology: Implications for the Practice of Medicine

    OpenAIRE

    Verny, Thomas R.

    1984-01-01

    Through the combined efforts of embryologists, neuro-embryologists, physiologists, obstetricians, pediatricians, nurses, psychiatrists, psychologists and many other health professionals a new science of pre- and perinatal psychology has begun to emerge. This science explores the psychology of conception, pregnancy, labor, delivery and the postpartum period, as well as the unborn and newborn child's intellectual and emotional development. Implications of this new knowledge for the family physi...

  1. Banking Strategy Demography - Future Population Trend: Implication for Banking

    OpenAIRE

    Teo, Lee Koon; Tripathi, Sanjay; Kazi, Zaid

    2010-01-01

    The world is going through a major shift in demographic structure that will affect the economies and global markets in a major way over the next few decades. While extensive research has been done on the macro-economic implications of demographic changes, very little research has been conducted on the demographic challenges at an industry level or for firms and on how these firms should react. The banking sector, in particular has received little attention. The project is initiated by the Glo...

  2. Implications of learning analytics for serious game design

    OpenAIRE

    Baalsrud Hauge, Jannicke; Fernández Manjón, Baltasar; Bellotti, Francesco; Fiucci, Giusy; Padrón-Nápoles, Carmen; Nadolski, Rob; WESTERA, Wim

    2014-01-01

    This paper addresses the implications of combining learning analytics and serious games for improving game quality, monitoring and assessment of player behavior, gaming performance, game progression, learning goals achievement, and user’s appreciation. We introduce two modes of serious games analytics: in-game (real time) analytics, and post-game (off-line) analytics. We also explain the GLEANER framework for in-game analytics and describe a practical example for off-line analytics. We conclu...

  3. Animal Models of Early Life Stress: Implications for Understanding Resilience

    OpenAIRE

    Lyons, David M.; Parker, Karen J.; Schatzberg, Alan F.

    2010-01-01

    In the mid-1950s, Levine and his colleagues reported that brief intermittent exposure to early life stress diminished indications of subsequent emotionality in rats. Here we review ongoing studies of a similar process in squirrel monkeys. Results from these animal models suggest that brief intermittent exposure to stress promotes the development of arousal regulation and resilience. Implications for programs designed to enhance resilience in human development are discussed.

  4. Minimalistic Simulation of Population Aging's Implications in the Slovak Republic

    OpenAIRE

    Rosenberg Zdeněk

    2014-01-01

    The main goal of the paper is to present transparent simulation of population's aging fiscal implications in the Slovak republic. The simulation uses projection of population aging and briefly analyses some of its aspects. It uses the number of people of each age and average government’s expenditures related to citizen of every year of age to calculate total expenditures for every year from present till 2050. The needed level of productivity of labor growth sufficient to balance budget in lon...

  5. Comparison between SLA and FLA and its Pedagogical Implications

    Institute of Scientific and Technical Information of China (English)

    王盼盼

    2013-01-01

      A distinction between two terms: SLA (second language acquisition) and FLA (foreign language acquisition) has been made with the purpose of clarifying these two related terms and providing pedagogical implications into EFLT (English as a foreign language teaching) in China. Three aspects have been taken into consideration to reveal the differences between SLA and FLA, namely the learning context, motivation and cultural perspectives.

  6. Evaluating the social and cultural implications of the internet

    OpenAIRE

    Brey, Philip

    2006-01-01

    Since the Internet's breakthrough as a mass medium, it has become a topic of discussion because of its implications for society. At one extreme, one finds those who only see great benefits and consider the Internet a tool for freedom, commerce, connectivity, and other societal benefits. At the other extreme, one finds those who lament the harms and disadvantages of the Internet, and who consider it a grave danger to existing social structures and institutions, to culture, morality and human r...

  7. Women in Marketing: Their Characteristics, Motivations, Challenges and Policy Implications

    OpenAIRE

    Ibok Nkanikpo Ibok; Etuk Samuel George

    2015-01-01

    Women constitute an important workforce in every society all over the world and contributions of women in every profession should be revisited with empirical facts. This study examines women in marketing; their characteristics, motivations and challenges using a survey method. With a sample of 60 respondents drawn across ten banks in Akwa Ibom State, the study reveals that characteristics, motivations and challenges of women has specific implications for national economic growth and marketing...

  8. Warming Oceans, Phytoplankton, and River Discharge: Implications for Cholera Outbreaks

    OpenAIRE

    Jutla, Antarpreet S; Akanda, Ali S.; Griffiths, Jeffrey K; Colwell, Rita; Islam, Shafiqul

    2011-01-01

    Phytoplankton abundance is inversely related to sea surface temperature (SST). However, a positive relationship is observed between SST and phytoplankton abundance in coastal waters of Bay of Bengal. This has led to an assertion that in a warming climate, rise in SST may increase phytoplankton blooms and, therefore, cholera outbreaks. Here, we explain why a positive SST-phytoplankton relationship exists in the Bay of Bengal and the implications of such a relationship on cholera dynamics. We f...

  9. Challenging the Computational Metaphor: Implications for How We Think

    OpenAIRE

    Stein, Lynn Andrea

    1999-01-01

    This paper explores the role of the traditional computational metaphor in our thinking as computer scientists, its influence on epistemological styles, and its implications for our understanding of cognition. It proposes to replace the conventional metaphor--a sequence of steps--with the notion of a community of interacting entities, and examines the ramifications of such a shift on these various ways in which we think.

  10. Obesity-related insulin resistance: implications for the surgical patient.

    Science.gov (United States)

    Tewari, N; Awad, S; Macdonald, I A; Lobo, D N

    2015-11-01

    In healthy surgical patients, preoperative fasting and major surgery induce development of insulin resistance (IR). IR can be present in up to 41% of obese patients without diabetes and this can rise in the postoperative period, leading to an increased risk of postoperative complications. Inflammation is implicated in the aetiology of IR. This review examines obesity-associated IR and its implications for the surgical patient. Searches of the Medline and Science Citation Index databases were performed using various key words in combinations with the Boolean operators AND, OR and NOT. Key journals, nutrition and metabolism textbooks and the reference lists of key articles were also hand searched. Adipose tissue has been identified as an active endocrine organ and the chemokines secreted as a result of macrophage infiltration have a role in the pathogenesis of IR. Visceral adipose tissue appears to be the most metabolically active, although results across studies are not consistent. Results from animal and human studies often provide conflicting results, which has rendered the pursuit of a common mechanistic pathway challenging. Obesity-associated IR appears, in part, to be related to inflammatory changes associated with increased adiposity. Postoperatively, the surgical patient is in a proinflammatory state, so this finding has important implications for the obese surgical patient. PMID:26028059

  11. Global warming: impacts and implications for South Asia

    Energy Technology Data Exchange (ETDEWEB)

    Pachauri, R.K. (Tata Energy Research Inst., New Delhi (India))

    1992-10-01

    The paper reviews the political and economic situation in South Asia, with emphasis on likely economic changes in the 1990s. The range of climatic changes that are likely to place on the South Asian sub-continent are discussed on the basis of projections made by the IPCC (Intergovernmental Panel on Climate Change). The impact of these changes in climate are evaluated with respect to agriculture, forestry, biological diversity, water resources and human health and social impacts. The problem of sea level rise and its implications for South Asia are also discussed, since these are likely to have disastrous implications for countries of the region. The special implications of global warming in the Ganga river basin are explored, culminating with a discussion on the imperatives of international co-operation among countries of the region to successfully face the collective threat of global warming. The paper indicates that with the different economic situation facing this region, international assistance from outside the region and close cooperation between the countries within the region would be the only effective strategy for the future. 10 refs., 1 fig., 8 tabs.

  12. Melanin and neuromelanin binding of drugs and chemicals: toxicological implications.

    Science.gov (United States)

    Karlsson, Oskar; Lindquist, Nils Gunnar

    2016-08-01

    Melanin is a polyanionic pigment that colors, e.g., the hair, skin and eyes. The pigment neuromelanin is closely related to melanin and is mainly produced in specific neurons of the substantia nigra. Certain drugs and chemicals bind to melanin/neuromelanin and are retained in pigment cells for long periods. This specific retention is thought to protect the cells but also to serve as a depot that slowly releases accumulated compounds and may cause toxicity in the eye and skin. Moreover, neuromelanin and compounds with high neuromelanin affinity have been suggested to be implicated in the development of adverse drug reactions in the central nervous system (CNS) as well as in the etiology of Parkinson's disease (PD). Epidemiologic studies implicate the exposure to pesticides, metals, solvents and other chemicals as risk factors for PD. Neuromelanin interacts with several of these toxicants which may play a significant part in both the initiation and the progression of neurodegeneration. MPTP/MPP(+) that has been casually linked with parkinsonism has high affinity for neuromelanin, and the induced dopaminergic denervation correlates with the neuromelanin content in the cells. Recent studies have also reported that neuromelanin may interact with α-synuclein as well as activate microglia and dendritic cells. This review aims to provide an overview of melanin binding of drugs and other compounds, and possible toxicological implications, with particular focus on the CNS and its potential involvement in neurodegenerative disorders. PMID:27311820

  13. Immunologic Changes Implicated in the Pathogenesis of Focal Segmental Glomerulosclerosis

    Directory of Open Access Journals (Sweden)

    Andreas Kronbichler

    2016-01-01

    Full Text Available Focal segmental glomerulosclerosis is a histological pattern on renal biopsy caused by diverse mechanisms. In its primary form, a circulatory factor is implicated in disease onset and recurrence. The natural history of primary FSGS is unpredictable, since some patients are unresponsive towards immunosuppressive measures. Immunologic changes, leading to a proinflammatory or profibrotic milieu, have been implicated in disease progression, namely, glomerular scarring, eventually leading to end-stage renal disease. Among these, interleukin-1ß, tumor-necrosis factor-α (TNF-α, and transforming growth factor-ß1 (TGF-ß1 have emerged as important factors. Translating these findings into clinical practice dampened the enthusiasm, since both TNF-α and TGF-ß1 blockade failed to achieve significant control of the disease. More recently, a role of the complement system has been demonstrated which in fact may be another attractive target in clinical practice. Rituximab, blocking CD20-bearing cells, demonstrated conflicting data regarding efficacy in FSGS. Finally, the T-cell costimulating molecule B7-1 (CD80 is implicated in development of proteinuria in general. Blockade of this target demonstrated significant benefits in a small cohort of resistant patients. Taken together, this review focuses on immunology of FSGS, attributable to either the disease or progression, and discusses novel therapeutic approaches aiming at targeting immunologic factors.

  14. 格蕴涵代数与MV-代数%Lattice Implication Algebras and MV-algebras

    Institute of Scientific and Technical Information of China (English)

    郭天榜

    1999-01-01

    Lattice implication algebras is an algebraic structure which is established by combining lattice and implication algebras. In this paper,the relationship between lattice implication algebras and MV-algebra was discussed,and then proved that both of the categorys of the two algebras are categorical equivalence. Finally,the infinitely distributivity in lattice implication algebras were proved.

  15. Exceptional visuospatial imagery in schizophrenia; implications for madness and creativity

    Directory of Open Access Journals (Sweden)

    Taylor eBenson

    2013-11-01

    Full Text Available Biographical and historical accounts suggest a link between scientific creativity and schizophrenia. Longitudinal studies of gifted children indicate that visuospatial imagery plays a pivotal role in exceptional achievements in science and mathematics. We asked whether visuospatial imagery is enhanced in individuals with schizophrenia (SZ. We compared SZ and matched healthy controls (HC on five visuospatial tasks tapping parietal and frontoparietal functions. Two aspects of visuospatial transformation, spatial location and mental imagery manipulation were examined with Paper Folding Test and Jigsaw Puzzle Task, respectively. Visuospatial intelligence was assessed with Ravens Progressive Matrices, which is associated with frontoparietal network activity. Hemispatial inattention implicating parietal function was assessed with line bisection task. Mediated by prefrontal cortex, spatial delayed response task was used to index working memory maintenance, which was impaired in SZ compared to HC. In contrast, SZ showed intact visuospatial intelligence and transformation of location. Further, SZ performed significantly better than HC on jigsaw puzzle task indicating enhanced mental imagery manipulation. Spatial working memory maintenance and mental imagery manipulation were strongly associated in HC but dissociated in SZ. Thus, we observed enhanced mental imagery manipulation in SZ but the dissociation of mental imagery from working memory suggests a disrupted frontoparietal network. Finally, while HC showed the expected leftward pseudoneglect, SZ showed increased rightward line bisection bias implicating left hemispatial inattention and impaired right parietal control of spatial attention. The current results chart a unique profile of impaired, spared and enhanced parietal-mediated visuospatial functions implicating parietal abnormalities as a biobehavioral marker for SZ. We discuss these results in relation to creative cognition.

  16. Climate Change Technology Scenarios: Energy, Emissions, and Economic Implications

    Energy Technology Data Exchange (ETDEWEB)

    Placet, Marylynn; Humphreys, Kenneth K.; Mahasenan, N Maha

    2004-08-15

    This report describes three advanced technology scenarios and various illustrative cases developed by staff of Pacific Northwest National Laboratory (PNNL) for the U.S. Climate Change Technology Program. These scenarios and illustrative cases explore the energy, emissions and economic implications of using advanced energy technologies and other climate change related technologies to reduce future emissions of greenhouse gases (GHGs). The cases were modeled using the Mini Climate Assessment Model (MiniCAM) developed by PNNL. The report describes the scenarios, the specifications for the cases, and the results. The report also provides background information on current emissions of GHGs and issues associated with stabilizing GHG concentrations.

  17. ECONOMIC CRISIS IMPLICATIONS ON PAEDIATRIC POPULATION’S HEALTH

    Directory of Open Access Journals (Sweden)

    Alina-Costina LUCA

    2015-04-01

    Full Text Available Once the global economic crisis occurred, shortly after the collapse of Lehman Brothers, trillions of dollars were lost on the stock exchange, hundreds of banks and investment funds in the US went bankrupt and thousands of companies were forced to declare bankruptcy. Its effects were felt then, in very short time also in Romania, following that in 2009, Romania went officially in recession. Beyond the financial implications the crisis has on the whole activity, regardless of the field, the economic and financial effects of the crisis on health and health policies can have very long term consequences.

  18. International and Cultural Implications on Internationalization Analysis of Multinational Firms

    Directory of Open Access Journals (Sweden)

    José G. Vargas-Hernández

    2015-08-01

    Full Text Available This paper is aims to analyze some of the institutional and cultural implications on internationalization analysis of multinational firms. The analysis begins questioning what the main institutional and cultural variables are considered in the involvement of internationalization of multinational firms. To answer this question, a literature review types approach in areas like internationalization of multinational firms based on institutional and cultural frameworks is followed. Secondly, these institutional and cultural variables are analyzed to integrate findings. Finally, the paper argues the need to design a better institutional and cultural balance among the development of a glocal-regional transformation, convergence and governance.

  19. Implications of WWW technologies for exchanging medical records

    Directory of Open Access Journals (Sweden)

    Maurice Dixon

    1999-09-01

    Full Text Available This article addresses some of the implications for medical record exchange of very recent developments in technology and tools that support the World Wide Web. It argues that XML (Extensible Mark-up Language is a very good enabling technology for medical record exchange. XML provides a much cheaper way of executing the exchange of medical information that circumvents the need for proprietary software. Use of XML can also simplify solutions to the problems associated with coping with the evolution of medical systems in time. However XML on its own does not resolve all the semantic heterogeneities.

  20. The implications of Wal-Mart's takeover of ASDA

    OpenAIRE

    Steve Burt; Leigh Sparks

    2001-01-01

    Wal-Mart is the world's largest retailer. Within the United Kingdom, retailing has generally been considered as a local or national activity. Wal-Mart's purchase of ASDA in 1999 illustrates the global scale of much modern retailing. In this paper we consider the implications of Wal-Mart's takeover of ASDA. First, the key drivers of Wal-Mart's business success are analysed. Second, the impact of Wal-Mart in Canada and Germany is considered. Third, the match of Wal-Mart with ASDA is examined. F...

  1. [Forensic Implications of Sleep-Associated Behavior Disorders].

    Science.gov (United States)

    Bumb, J M; Schredl, M; Dreßing, H

    2015-11-01

    Parasomnias represent a category of disorders that involve complex behaviors or emotional experiences, arising from or occurring during sleep, which might be also associated with (incomplete) awakening. These phenomena are classified as REM- or Non-REM-parasomnias. In particular the latter, including confusional arousal, sleepwalking and sleep terrors but also REM-sleep behavior disorder might result in criminal consequences. Using polysomnography, the pathophysiological mechanisms of these disorders have been investigated thoroughly. Nevertheless, in German literature, forensic implications of complex behaviors arising from sleep disorders have only been described insufficiently. Here we describe the most relevant parasomnias and also how to proceed in the context of forensic assessments. PMID:26633841

  2. Implications of Recent Measurements of Hadronic Charmless B Decays

    OpenAIRE

    Cheng, Hai-Yang; Yang, Kwei-Chou

    1999-01-01

    Implications of recent CLEO measurements of hadronic charmless B decays are discussed. (i) Employing the Bauer-Stech-Wirbel (BSW) model for form factors as a benchmark, the $B\\to\\pi^+\\pi^-$ data indicate that the form factor $F_0^{B\\pi}(0)$ is smaller than that predicted by the BSW model, whereas the data of $B\\to\\omega\\pi, K^*\\eta$ imply that the form factors $A_0^{B\\omega}(0), A_0^{BK^*}(0)$ are greater than the BSW model's values. (ii) The tree-dominated modes $B\\to\\pi^+\\pi^-, \\rho^0\\pi^\\p...

  3. Implications of plant glycans in the development of innovative vaccines.

    Science.gov (United States)

    Rosales-Mendoza, Sergio; Salazar-González, Jorge A; Decker, Eva L; Reski, Ralf

    2016-07-01

    Plant glycans play a central role in vaccinology: they can serve as adjuvants and/or delivery vehicles or backbones for the synthesis of conjugated vaccines. In addition, genetic engineering is leading to the development of platforms for the production of novel polysaccharides in plant cells, an approach with relevant implications for the design of new types of vaccines. This review contains an updated outlook on this topic and provides key perspectives including a discussion on how the molecular pharming field can be linked to the production of innovative glycan-based and conjugate vaccines. PMID:26890067

  4. On the Correctness of Quantum Raychaudhuri Equation and its Implications

    CERN Document Server

    Lashin, E I

    2016-01-01

    Regardless of the problems associated with the Bohmian interpretation of quantum mechanics, we carefully examine the approach of quantum Raychaudhuri equation (QRE) based on quantal (Bohmian) trajectories. We find that the whole procedure is full of problematic points, on both physical relevancy and mathematical correctness. In particular, we illustrate the problems associated with the technical derivation of QRE, as well as its invalid physical implications. Thus, all claims concerning the inevitability of focusing and the formation of conjugate points, including the singularity evading, are, to us, not valid.

  5. Cosmological implications of Higgs field fluctuations during inflation

    CERN Document Server

    Grobov, A V; Rubin, S G

    2016-01-01

    Cosmological implications of Higgs field fluctuations during inflation are considered. This study is based on the Standard Model and the standard quadratic model of chaotic inflation where the Higgs field is minimally coupled to gravity and has no direct coupling to the inflaton. In the Standard model the renormalisation group improved effective potential develops an instability (an additional minimum and maximum) at large field values. It is shown that such a new maximum should take place at an energy scale above $10^{14} \\;\\text{GeV},$ otherwise a universe like ours is extremely unlikely. The extension to the case of the Higgs field interacting with the inflaton field is discussed.

  6. Bacterial motility in the sea and its ecological implications

    DEFF Research Database (Denmark)

    Grossart, Hans-Peter; Riemann, Lasse; Azam, F.

    2001-01-01

    Motility could be an important adaptation of heterotrophic bacteria and archaea, and it may have ecological and biogeochemical implications. However, the limited observations so far show that only a small fraction (=10%) of bacteria is motile. We report a systematic 10 mo long field study off...... the coast of La Jolla, California, as well as a mesocosm study to examine bacterial motility and its relationship to environmental variables. Dark-field microscopy revealed periods of sustained low (fall and winter, bacteria (% motile......). Bacteria in natural seawater did not swim constantly nor at constant speeds; over 40% swam bacteria...

  7. Barriers to Research and Implications for Training Counselors

    Directory of Open Access Journals (Sweden)

    James R Ruby

    2013-03-01

    Full Text Available Research is an important part of quality clinical practice in the field of counseling. This study addresses the constraints that produce a gap in master’s level practitioner research among counselors in Illinois. Ninety-nine master’s level clinicians responded to surveys and answered a series of questions regarding what constrains them from being more involved in research. These respondents provided valuable feedback regarding possible recommendations for training that might encourage increased research activity for future master’s level counselors. Training improvements such as mentored research activity and training in less complex research methods were indicated. Keywords: Clinical practice, Implications, Barriers to research, less complex research

  8. Can resistive breathing injure the lung? Implications for COPD exacerbations

    Directory of Open Access Journals (Sweden)

    Vassilakopoulos T

    2016-09-01

    Full Text Available Theodoros Vassilakopoulos, Dimitrios Toumpanakis Pulmonary and Critical Care Medicine, Medical School, National and Kapodistrian University of Athens, Greece Abstract: In obstructive lung diseases, airway inflammation leads to bronchospasm and thus resistive breathing, especially during exacerbations. This commentary discusses experimental evidence that resistive breathing per se (the mechanical stimulus in the absence of underlying airway inflammation leads to lung injury and inflammation (mechanotransduction. The potential implications of resistive breathing-induced mechanotrasduction in COPD exacerbations are presented along with the available clinical evidence. Keywords: resistive breathing, COPD, mechanotransduction, bronchoconstriction, inflammation

  9. Implications of lepton nonuniversality in the beauty sector

    CERN Document Server

    Giri, A; Sahoo, S

    2016-01-01

    The phenomenon of CP violation in the standard model (SM) framework and the decay dynamics have been established from the data obtained from the B factories and so far we have not seen anything new. Nevertheless, there have been instances of deviations in many measured observables in the flavor sector, as far as the data and predictions are concerned. Here we will mention some deviations obtained in measurements related to lepton universality, as seen from the data, and try to understand their implications. To accommodate the observed data we will consider a leptoquark model, which seems to be one interesting model beyond the SM.

  10. Support mechanisms and risk: Implications on the Nordic electricity system

    DEFF Research Database (Denmark)

    Kitzing, Lena; Ravn, Hans

    2013-01-01

    Investments in renewable energy projects, such as offshore wind parks, are very much dependent on financial support. The type of policy instrument chosen for such support determines investors' exposure to market risk, and thus influences which rate of return they expect to achieve. We make...... a stochastic analysis for the Nordic electricity system by conducting simulations with the energy system model Balmorel and by applying the mean-standard deviation approach of modern portfolio theory to quantify risk implications of policy instruments for an exemplary offshore wind park. The analysis reveals...

  11. Implications of perspective in teaching objects first and object design

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    2005-01-01

    There are an increasing number of books published on the important topics of "object-oriented programming" and "object-oriented design" for use in education. However, object-orientation can be viewed from a number of different perspectives---each perspective having its benefits and liabilities...... of perspective with the unfortunate effect that our students leave our courses with limited design abilities. We present a coarse-grained classification, discuss implications of perspective in a teaching context, and illustrate consequences using a small case study. Our main point is that teachers should...... be aware of the different perspectives, and that all perspectives are important for students to achieve high quality designs...

  12. The FIRO model of family therapy: implications of factor analysis.

    Science.gov (United States)

    Hafner, R J; Ross, M W

    1989-11-01

    Schutz's FIRO model contains three main elements: inclusion, control, and affection. It is used widely in mental health research and practice, but has received little empirical validation. The present study is based on factor analysis of the resources to FIRO questionnaire of 120 normal couples and 191 couples who were attending a clinic for marital/psychiatric problems. Results confirmed the validity of the FIRO model for women only. The differences between the sexes reflected a considerable degree of sex-role stereotyping, the clinical implications of which are discussed.

  13. China'S Integration Into the World Economy; Implications for Developing Countries

    OpenAIRE

    Yongzheng Yang

    2003-01-01

    Although the rest of the world had waited a long time for China to open up, feelings were mixed when it actually did and began to integrate rapidly with the world economy. With the country’s recent accession to the World Trade Organization (WTO), many of its trading partners are increasingly concerned that China’s competition in the world goods and capital markets may adversely affect their own growth prospects. This paper examines the implications of China’s WTO accession for other developin...

  14. Implications of a Time-Varying Fine Structure Constant

    CERN Document Server

    Alfonso-Faus, A

    2002-01-01

    Much work has been done after the possibility of a fine structure constant being time-varying. It has been taken as an indication of a time-varying speed of light. Here we prove that this is not the case. We prove that the speed of light may or may not vary with time, independently of the fine structure constant being constant or not. Time variations of the speed of light, if present, have to be derived by some other means and not from the fine structure constant. No implications based on the possible variations of the fine structure constant can be imposed on the speed of light.

  15. TQM as a managerial innovation: research issues and implications.

    Science.gov (United States)

    Kaluzny, A D; McLaughlin, C P; Jaeger, B J

    1993-05-01

    TQM is a managerial innovation that is likely to have profound consequences on the delivery of health services. As an innovation, it is important that attention be given to the fundamental research issues associated with implementation and impact. Using a variance and process perspective, selected research issues are identified within organizations and among work units within these organizations. The variance perspective at both the organizational and work unit level considers the explanation of impact and adoption at a particular point in time. The process perspective considers the particular steps or events in the overall adoption process. The managerial implications for each perspective are discussed.

  16. Fly-in/Fly-out: Implications for Community Sustainability

    OpenAIRE

    Keith Storey

    2010-01-01

    “Fly-in/fly-out†is a form of work organization that has become the standard model for new mining, petroleum and other types of resource development in remote areas. In many places this “no town†model has replaced that of the “new town.†The work system has both beneficial and adverse implications for the sustainability of both existing communities near new resource developments and for the more distant communities from which workers are drawn. This paper explores these outcomes dra...

  17. Improving statistical reasoning theoretical models and practical implications

    CERN Document Server

    Sedlmeier, Peter

    1999-01-01

    This book focuses on how statistical reasoning works and on training programs that can exploit people''s natural cognitive capabilities to improve their statistical reasoning. Training programs that take into account findings from evolutionary psychology and instructional theory are shown to have substantially larger effects that are more stable over time than previous training regimens. The theoretical implications are traced in a neural network model of human performance on statistical reasoning problems. This book apppeals to judgment and decision making researchers and other cognitive scientists, as well as to teachers of statistics and probabilistic reasoning.

  18. Implications of plant glycans in the development of innovative vaccines.

    Science.gov (United States)

    Rosales-Mendoza, Sergio; Salazar-González, Jorge A; Decker, Eva L; Reski, Ralf

    2016-07-01

    Plant glycans play a central role in vaccinology: they can serve as adjuvants and/or delivery vehicles or backbones for the synthesis of conjugated vaccines. In addition, genetic engineering is leading to the development of platforms for the production of novel polysaccharides in plant cells, an approach with relevant implications for the design of new types of vaccines. This review contains an updated outlook on this topic and provides key perspectives including a discussion on how the molecular pharming field can be linked to the production of innovative glycan-based and conjugate vaccines.

  19. Exploring accountability of clinical ethics consultants: practice and training implications.

    Science.gov (United States)

    Weise, Kathryn L; Daly, Barbara J

    2014-01-01

    Clinical ethics consultants represent a multidisciplinary group of scholars and practitioners with varied training backgrounds, who are integrated into a medical environment to assist in the provision of ethically supportable care. Little has been written about the degree to which such consultants are accountable for the patient care outcome of the advice given. We propose a model for examining degrees of internally motivated accountability that range from restricted to unbounded accountability, and support balanced accountability as a goal for practice. Finally, we explore implications of this model for training of clinical ethics consultants from diverse academic backgrounds, including those disciplines that do not have a formal code of ethics relating to clinical practice.

  20. Implications of current constraints on parton charge symmetry

    Energy Technology Data Exchange (ETDEWEB)

    J. T. Londergan; A. W. Thomas

    2005-11-01

    For the first time, charge symmetry breaking terms in parton distribution functions have been included in a global fit to high energy data. We review the results obtained for both valence and sea quark charge symmetry violation and compare these results with the most stringent experimental upper limits on charge symmetry violation for parton distribution functions, as well as with theoretical estimates of charge symmetry violation. The limits allowed in the global fit would tolerate a rather large violation of charge symmetry. We discuss the implications of this for various observables, including extraction of the Weinberg angle in neutrino DIS and the Gottfried and Adler sum rules.

  1. Stories: implications for nursing ethics and respect for another.

    Science.gov (United States)

    Milton, Constance L

    2004-07-01

    Stories are narratives cocreated in the human-universe process which reflect authors' priority projects, ideas, and creative artistry. These articulations may be utilized as methods for understanding health and quality of life in the discipline of nursing. Stories are living entities of community that may be used for research, education, and practice. They are vital tools for professionals asking ethical questions about doing what is right in the human-universe-health process. This article shall examine the use of stories and provide notions for further ethical thinking and implications for human regard from a nursing theoretical perspective. PMID:15200721

  2. Considerations on the criteria, parameters and tax implications of depreciation

    Directory of Open Access Journals (Sweden)

    Dorel Mateş

    2012-01-01

    Full Text Available The literature presents several methods of depreciation. In Romania, not all depreciation methods are recommended by existing legislation. In this paper we propose to address through the income tax three methods of depreciation of assets, which are recommended by our country's legislation, and to highlight the tax benefits of their application within the entities. In the first part we propose to define what are the criteria for evaluating of a assets depreciation and accounting parameters of the assets depreciation. In the second part of the paper will be presented depreciation methods as linear, diminishing and accelerating with the tax implications.

  3. Tourist activated networks: Implications for dynamic packaging systems in tourism

    DEFF Research Database (Denmark)

    Zach, Florian; Gretzel, Ulrike; Fesenmaier, Daniel R.

    2008-01-01

    structure. The results indicate that the tourist activated network for the destination is rather sparse and that there are clearly differences in core and peripheral nodes. The findings illustrate the structure of a tourist activated network and provide implications for technology design and tourism......This paper discusses tourist activated networks as a concept to inform technological applications supporting dynamic bundling and en-route recommendations. Empirical data was collected from travellers who visited a regional destination in the US and then analyzed with respect to its network...

  4. Toxic Epidermal Necrolysis induced by rarely implicated drugs

    Directory of Open Access Journals (Sweden)

    Sujit Rajagopalan

    2012-01-01

    Full Text Available Toxic Epidermal Necrolysis (TEN and Steven-Johnson Syndrome (SJS are serious disorders commonly caused as idiosyncratic reactions to drugs, the most common ones being oxicams, anticonvulsants, allopurinol, and sulfonamides. We present a case of TEN in a patient who developed the lesions after ingesting multiple drugs including paracetamol, metoclopramide, antihistamines, and multivitamins. These drugs have rarely been implicated in this disorder. The suspected drugs in this case were paracetamol and metoclopramide. However, the role of other drugs could not be ruled out definitely. The patient was managed with antibiotics, corticosteroids, and parenteral fluids and recovered well.

  5. Extended superposed quantum-state initialization using disjoint prime implicants

    International Nuclear Information System (INIS)

    Extended superposed quantum-state initialization using disjoint prime implicants is an algorithm for generating quantum arrays for the purpose of initializing a desired quantum superposition. The quantum arrays generated by this algorithm almost always use fewer gates than other algorithms and in the worst case use the same number of gates. These improvements are achieved by allowing certain parts of the quantum superposition that cannot be initialized directly by the algorithm to be initialized using special circuits. This allows more terms in the quantum superposition to be initialized at the same time which decreases the number of gates required by the generated quantum array.

  6. Survival of microorganisms in smectite clays - Implications for Martian exobiology

    Science.gov (United States)

    Moll, Deborah M.; Vestal, J. R.

    1992-01-01

    The survival of Baccillus subtilis, Azotobacter chroococcum, and the enteric bacteriophage MS2 has been examined in clays representing terrestrial (Wyoming type montmorillonite) and Martian (Fe3+ montmorillonite) soils exposed to terrestrial and Martian environmental conditions of temperature and atmospheric composition and pressure. An important finding is that MS2 survived simulated Mars conditions better than the terrestrial environment, probably owing to stabilization of the virus caused by the cold and dry conditions of the simulated Mars environment. This finding, the first published indication that viruses may be able to survive in Mars-type soils, may have important implications for future missions to Mars.

  7. Faceless Person Recognition; Privacy Implications in Social Media

    OpenAIRE

    Oh, Seong Joon; Benenson, Rodrigo; Fritz, Mario; Schiele, Bernt

    2016-01-01

    As we shift more of our lives into the virtual domain, the volume of data shared on the web keeps increasing and presents a threat to our privacy. This works contributes to the understanding of privacy implications of such data sharing by analysing how well people are recognisable in social media data. To facilitate a systematic study we define a number of scenarios considering factors such as how many heads of a person are tagged and if those heads are obfuscated or not. We propose a robust ...

  8. Bilateral lingual-facial trunk: anatomic and clinical implications.

    Science.gov (United States)

    Troupis, T; Michalinos, A; Kakisis, J; Natsis, K; Sofidis, G; Skandalakis, P

    2015-01-01

    Common origin of lingual and facial artery is a relatively frequent anatomic varia-tion. Instead, bilateral lingual-facial trunk has been described only sparsely in the literature. In this report authors describe and analyse a case of bilateral common lingual-facial trunk in the context of its anatomical, clinical and embryological implications. We also describe possible consequences in performance of elective and emergent surgical operations and modification in surgical techniques that should be considered. We believe that surgeons should be suspicious for this variation's existence and keep alternative solutions in their armentarium.

  9. The Implications of Interactions for Science and Philosophy

    CERN Document Server

    Gershenson, Carlos

    2011-01-01

    Reductionism has dominated science and philosophy for centuries. Complexity has recently shown that interactions---which reductionism neglects---are relevant for understanding phenomena. When interactions are considered, reductionism becomes limited in several aspects. In this paper, I argue that interactions imply non-reductionism, non-materialism, non-predictability, non-Platonism, and non-nihilism. As alternatives to each of these, holism, informism, adaptation, contextuality, and meaningfulness are put forward, respectively. A worldview that includes interactions not only describes better our world, but can help to solve many open scientific, philosophical, and social problems caused by implications of reductionism.

  10. On Fundamental Implications of Intergalactic Magnetic Field Observations

    CERN Document Server

    Vachaspati, Tanmay

    2016-01-01

    Helical intergalactic magnetic fields at the $\\sim 10^{-14}~{\\rm G}$ level on $\\sim 10~{\\rm Mpc}$ length scales are indicated by current gamma ray observations. The existence of magnetic fields in cosmic voids and their non-trivial helicity suggest that they must have originated in the early universe and thus have implications for the fundamental interactions. I combine present knowledge of the observational constraints and the dynamics of cosmological magnetic fields to derive characteristics that would need to be explained by the magnetic field generation mechanism. The importance of CP violation and a possible crucial role for chiral effects in the early universe are pointed out.

  11. The etiology and exercise implications of sarcopenia in the elderly

    Directory of Open Access Journals (Sweden)

    Jie Yu

    2015-06-01

    Full Text Available An increasing aging population greatly impacts health care services worldwide. A large percentage of healthcare expenditures for seniors arise from the negative outcomes of muscle loss, also known as sarcopenia. Aging-related losses of muscle strength and quality impair balance, walking ability and endurance and cause negative events such as falls, incident disability and frailty. This review systemically explores the significance of sarcopenia in the elderly and addresses several important physiological mechanisms of sarcopenia. The implications of crucial exercise regimens that improve muscle strength and delay the onset of sarcopenia are also discussed.

  12. 0Adipose-derived stem cells: Implications in tissue regeneration

    Institute of Scientific and Technical Information of China (English)

    Wakako; Tsuji; J; Peter; Rubin; Kacey; G; Marra

    2014-01-01

    Adipose-derived stem cells(ASCs) are mesenchymal stem cells(MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differ-entiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs dam-aged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration.

  13. Recent Changes in Earth Oblateness: Causes and Implications

    Science.gov (United States)

    Dickey, J. O.; Marcus, S. L.; de Viron, O.; Fukumori, I.

    2002-12-01

    Fluctuations in the Earth's dynamic oblateness (J2) as measured by space geodetic technique over more than two decades, are dominated by a seasonal cycle and a negative trend induced mostly by post-glacial rebound. However, since 1998 the Earth's J2 has begun to increase, indicating a pronounced global-scale mass redistribution within the Earth system from high to low latitudes. Cox and Chao reported this discovery in Science (August 2, 2002) and left the sources of this anomaly unresolved. Here, we present the results of our analysis, identifying the source and discussing the implications.

  14. The 'voice of care': implications for bioethical education.

    Science.gov (United States)

    Carse, A L

    1991-02-01

    This paper examines the 'justice' and 'care' orientations in ethical theory as characterized in Carol Gilligan's research on moral development and the philosophical work it has inspired. Focus is placed on challenges to the justice orientation--in particular, to the construal of impartiality as the mark of the moral point of view, to the conception of moral judgment as essentially principle-driven and dispassionate, and to models of moral responsibility emphasizing norms of formal equality and reciprocity. Suggestions are made about the implications of these challenges, and of the care orientation in ethics, for the ethical theory taught, the issues addressed, and the skills and sensitivities encouraged through bioethical education.

  15. Opposite policy implications in the theory of money and banking

    Directory of Open Access Journals (Sweden)

    Jefferson D. P. Bertolai

    2013-12-01

    Full Text Available The recent financial crisis creates a demand for welfare-based models of financial regulation and liquidity shortages. In this paper, we review policy implications from two cornerstone models and show that they imply different responses in terms of intertemporal returns of financial liabilities. In the first case, a version of the Cavalcanti and Wallace (1999, random-matching model, monitored agents are led to promote inflation in bank-issued money. In the second case, a sequential-service version of the Diamond and Dybvig (1983 model of bank runs with insolvency, increases in long-run returns can prevent bank runs by reducing the provision of liquidity.

  16. Cosmological implications of quantum entanglement in the multiverse

    Directory of Open Access Journals (Sweden)

    Sugumi Kanno

    2015-12-01

    Full Text Available We explore the cosmological implications of quantum entanglement between two causally disconnected universes in the multiverse. We first consider two causally separated de Sitter spaces with a state which is initially entangled. We derive the reduced density matrix of our universe and compute the spectrum of vacuum fluctuations. We then consider the same system with an initially non-entangled state. We find that due to quantum interference scale dependent modulations may enter the spectrum for the case of initially non-entangled state. This gives rise to the possibility that the existence of causally disconnected universes may be experimentally tested by analyzing correlators in detail.

  17. Chemical Expansion: Implications for Electrochemical Energy Storage and Conversion Devices

    DEFF Research Database (Denmark)

    Bishop, S.R.; Marrocchelli, D.; Chatzichristodoulou, Christodoulos;

    2014-01-01

    Many energy-related materials rely on the uptake and release of large quantities of ions, for example, Li+ in batteries, H+ in hydrogen storage materials, and O2− in solid-oxide fuel cell and related materials. These compositional changes often result in large volumetric dilation of the material...... modeling and an overview of factors impacting chemical expansion. We discuss the implications of chemical expansion for mechanical stability and functionality in the energy applications above, as well as in other oxide-based systems. The use of chemical expansion as a new means to probe other materials...

  18. Squark Flavor Implications from B --> K(*) l+ l-

    OpenAIRE

    Behring, Arnd; GROSS, Christian; Hiller, Gudrun; Schacht, Stefan

    2012-01-01

    Recent experimental and theoretical progress regarding B --> K(*) l+ l- decays led to improved bounds on the Wilson coefficients C_9 and C_10 of four-fermion operators of the |Delta B|=|Delta S|=1 effective Hamiltonian. We analyze the resulting implications on squark flavor violation in the MSSM and obtain new constraints on flavor-changing left-right mixing in the up-squark-sector. We find the dimensionless flavor mixing parameter (delta^u_23)_LR, depending on the flavor-diagonal MSSM masses...

  19. Essential aspects and practical implications of sexual identity

    Directory of Open Access Journals (Sweden)

    Adalberto Campo-Arias

    2010-06-01

    Full Text Available Sexual identity is a multidimensional construct that includes sex identity, gender identity, socio-sexual identity, and erotic identity. Sexual identity has theoretical and practical implications for sexual and reproductive health. For adults, concordance among biological sex, gender and role identity, and erotic identity is expected. However, 10% of the general population reports itself as non-heterosexual and another significant percent shows discordant sexual behavior with sexual identity. This narrative review clarifies the concepts of sexual identity, gender identity, socio-sexual identity, and erotic identity and presents some practical issues of an inappropriate use of these constructs in public health.

  20. Essential aspects and practical implications of sexual identity

    Directory of Open Access Journals (Sweden)

    Adalberto Campo-Arias

    2010-06-01

    Full Text Available Sexual identity is a multidimensional construct that includes sex  identity, gender identity, socio-sexual identity, and erotic identity. Sexual  identity has theoretical and practical implications for sexual and reproductive health. For adults, concordance among biological sex, gender and role identity, and erotic identity is expected. However, 10% of the general population reports itself as non-heterosexual and another significant percent shows discordant sexual behavior with sexual identity. This narrative review clarifies the concepts of sexual identity, gender identity, socio-sexual identity, and erotic identity and presents some practical issues of an inappropriate use of these constructs in public health.