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Sample records for ciclo risk study

  1. Riesgo cardiovascular del paciente hipertenso con seguimiento prolongado en atención primaria. El efecto del envejecimiento (ciclo risk study

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    Luis García-Ortiz

    2007-01-01

    Full Text Available Fundamento La evolución del riesgo cardiovascular estimado, puede servir para valorar la efectividad de las diferentes intervenciones terapéuticas que se realizan en pacientes con seguimiento habitual en las consultas del médico de familia. El objetivo de este trabajo es comparar diferentes sistemas de evaluación del efecto de las intervenciones preventivas en la evolución del riesgo coronario en el seguimiento a largo plazo de personas hipertensas en Atención Primaria. Métodos: Estudio descriptivo longitudinal con seguimiento de 8.42 pacientes hipertensos de 34 a 70 años durante 6 años en dos centros de atención primaria, con una intervención de mejora de calidad (ciclo de mejora en el último año en uno de ellos. El seguimiento mínimo en atención primaria previo al inicio del estudio fue de dos años. Las variables principales fueron edad y sexo, presión arterial, lípidos, tabaquismo, diabetes y riesgo cardiovascular (RCV(Framingham-Wilson en la situación real y considerando constante la edad en el primer supuesto y los factores de riesgo en el segundo y el riesgo relativo. Resultados: Se encontró un descenso de la presión arterial sistólica y diastólica de 11,78 mmHg (IC95%:10,51-13,05 y 8,83 mmHg (IC95%:8,13-9,53 respectivamente y LDL-Colesterol 15,94 mg/dl (IC95%:11,77-20,12, un ascenso del HDLColesterol de 7,53 mg/dl (IC95:6,39-8,66, disminución del tabaquismo del 31% y un aumento de diabéticos. El riego coronario disminuyó 1,40(IC95%:0,87-1,93 puntos porcentuales, el RCV con edad constante descendió 3,84(IC95%:3,35-4,33 y con factores de riesgo constantes incrementó 3,06(IC95%:2,82- 3,29. El Riesgo relativo descendió de 2,50 a 1,85. Conclusiones: El envejecimiento puede enmascarar el efecto logrado por la atención sanitaria en el control del riesgo cardiovascular absoluto. El riesgo relativo podría ser una alternativa para monitorizar el seguimiento.

  2. Ciclo Basico Polivalente (Basic Comprehensive Courses of Study).

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    Boletin del Centro Nacional de Documentacion e Informacion Educativa, 1970

    1970-01-01

    This article discusses the creation of comprehensive secondary schools in Argentina to meet the diversified goals of the population in any given geographical region. The plan described here provides for the creation of several basic-study cycles within one school so that students may pursue courses in commercial, technical, and academic fields.…

  3. Das séries aos ciclos de estudos: o desafio da (descontinuidade De los grados a los ciclos de estudios: el desafío de la (descontinuidad From grades to study cycles: the challenge of the (discontinuity

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    Doralice Aparecida Paranzini Gorni

    2009-12-01

    ón formativa en su cotidiano. Este trabajo ha sido basado en una encuesta cualitativa que propuso la adecuación de la evaluación del alumno a la de la escuela en ciclos de estudios e fue realizado de 2004 a 2006 en cuatro etapas: grupo de estudios realizado con el profesorado del 1º al 4º grados juntamente con el cuadro técnico-pedagógico de dicha escuela; asesoramiento individual al profesorado para trabajarse en la planificación anual y bimestral; elaboración de fichas para el acompañamiento del desempeño de los alumnos; asesoramiento al profesorado cuanto al relleno de las fichas de sus respectivas clases, además de la realización de reuniones mensuales para evaluarse y encaminar las dificultades encontradas, visando la construcción de un instrumento que posibilitara la elaboración de un método de evaluación continuado y reflexivo, integrado a la práctica pedagógica. Se obtuvo un resultado positivo junto a 50% del profesorado. Es necesario resaltar la necesidad de hacer el profesorado efectivo en las escuelas por mediante la elaboración de políticas que combatan el elevado grado rotativo de profesores y que les garanticen condiciones para que ellos se envuelvan en proyectos que contribuyan para la mejoría de la calidad de la práctica pedagógica y para enfrentar las dificultades existentes en el cotidiano de la escuela.During the 1980's, the reorganization of the Brazilian traditional grades of elementary school into cycles began, based on the principle of enlarging the students' learning period and on the idea of continuity. This study aimed to investigate the evaluation practices in a public school organized in cycles, as well as the necessary conditions to implement the formative assessment in their daily lives. A qualitative study held from 2004 to 2006 proposed the adequacy of the students' evaluation. The research was developed in four stages: a study group with the teachers and the technical-pedagogical body was carried out; assistance to

  4. Performance study of a combined cycle power plant with integral gasification; Estudio del desempeno de una planta de potencia de ciclo combinado con gasificacion integral

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Rocha, Jose Clemente

    2007-04-15

    integration to an existing combined cycle power plant. The strategic location of the Tula combined cycle, which is adjacent to Miguel Hidalgo refinery, presents the opportunity of applying the gasification technology as a viable alternative: firstly, for the use of petroleum coke that at this moment is been produced in the Mexican refineries or using the petroleum coke that could be produced in the adjacent refinery; and secondly, by the possibility of applying the concept of reconfiguration of the Tula combined cycle to operate as CCGI, with the objective of improving its thermal regime, its generation capacity and its global thermal efficiency. This way, every study realized to predict the performance of an existing combined cycle power plant using a gasification process and operating under the concept of combined cycle with integrated gasification (CCGI) is of utility for later studies, that consider the concept of reconfiguration of existing conventional power plants in Mexico, for example, the coal-electric or fossil fuel, which use polluting fuels such as coal or fuel oil, so that a reconfiguration using the gasification technology could replace these fuels reducing the emission of polluting agents to the atmosphere. Also, this study would be useful for studies that contemplate the installation of a gasification system in an adjacent refinery to a combined cycle in order to take advantage of the coke produced in this one and to improve the thermal regime, the global thermal efficiency, and the electric generation capacity of the combined cycle. [Spanish] A nivel mundial, en la ultima decada se ha incrementado el interes por usar el coque del petroleo como combustible en la generacion limpia de energia aplicando la tecnologia de gasificacion. Este interes se debe principalmente el incremento en la produccion del coque de petroleo como consecuencia del procesamiento de mayores volumenes de crudo pasado en las refinerias y al incremento en el rendimiento de los productos

  5. Séries no ensino privado, ciclos no público: um estudo em Belo Horizonte Grades in private schools, learning cycles in public schools: a study carried out in Belo Horizonte

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    Paulo Roberto Vidal de Negreiros

    2005-05-01

    Full Text Available O objetivo deste estudo é entender o fenômeno que tem ocorrido nas esferas de ensino público e privado no Brasil no que diz respeito à aplicação do art. 23 da Lei de Diretrizes e Bases da Educação Nacional - LDB -, Lei n. 9.394/96, que trata da organização dos tempos escolares. Ao flexibilizar e delegar a autonomia aos estabelecimentos de ensino na escolha da organização dos tempos escolares esta lei acabou provocando uma situação diversificada. Os dados revelam que a rede pública movimenta-se mais rapidamente para uma organização em ciclos enquanto que a rede privada de ensino mostra-se mais propensa à continuidade da organização seriada. Dados estatísticos recentes, fornecidos pelo Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira - Inep - comprovam isso. As razões pelas quais os estabelecimentos de ensino público adotam o sistema de ciclos têm sido objeto de muitas publicações. No entanto, quando a escola particular é o foco dessa questão, não se sabe ao certo quais as razões da não adesão à proposta dos ciclos e nem os motivos da continuidade do sistema seriado.The objective of this study is to understand what has been occurring in the spheres of public and private education in Brazil, concerning the application of art. 23 of the Guidelines and Bases Act of Education - LDB -, Law n. 9.394/96, which deals with the organization of school times. This law has caused a diversified situation by allowing flexibility and delegating autonomy to teaching institutions to decide on school time's organization. The data indicate that the public schools are moving more quickly towards an organization based on cycles, whereas the private ones are more inclined to keep grades. Recent statistic data, supplied by the National Institute of Pedagogical Studies and Research Anísio Teixeira - Inep -, prove it. The reasons why public teaching institutions adopt the learning cycle have been discussed in many

  6. Polibutadieno alto-cis: estudo viscosimétrico em tolueno e ciclo-hexano High-cis polybutadiene: viscometric study in toluene and cyclohexane

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    Ivana L. Mello

    2006-03-01

    Full Text Available Foram realizadas medidas viscosimétricas, em soluções de tolueno e ciclo-hexano, a 30°C, com polibutadieno alto-cis, sintetizado com catalisadores à base de neodímio. Foram empregadas diferentes equações para determinar os valores de viscosidade intrínseca: Huggins; Kraemer; Martin; e Schulz-Blaschke, por extrapolação gráfica; e Solomon-Ciuta; Deb-Chanterjee e; novamente, Schulz-Blaschke, por determinação por um único ponto. Os valores de viscosidade intrínseca obtidos pelos dois métodos (extrapolação gráfica e por um único ponto foram comparados a fim de se verificar a validade da determinação por um único ponto para os sistemas analisados, bem como determinar que equação fosse a mais adequada para esse tipo de cálculo. Foram calculadas as constantes viscosimétricas de Huggins, Kraemer e Schulz-Blaschke e foi feita uma análise da qualidade do solvente, levando-se em conta também os valores do parâmetro de solubilidade de Hildebrand dos solventes e do polímero. Foi determinada a distância média quadrática entre as extremidades das cadeias poliméricas por meio da equação de Flory, para tal foram utilizados os dados viscosimétricos obtidos, bem como os pesos moleculares determinados por viscosimetria e por cromatografia de exclusão por tamanho. Verificou-se que o método de determinação por um único ponto foi apropriado para o polibutadieno alto-cis, tanto para o cálculo de viscosidade intrínseca quanto de peso molecular. Em tolueno, a equação de Solomon-Ciuta foi a mais adequada, ao passo que a equação de Deb-Chanterjee foi mais apropriada para o polímero em ciclo-hexano. Verificou-se também que o tolueno foi o melhor solvente para o polibutadieno em função dos maiores valores de viscosidade intrínseca e de distância média quadrática entre os extremos da cadeia polimérica. Os valores obtidos para as constantes viscosimétricas confirmaram essa observação.Viscometric measurements, in

  7. A study on domino effect in nuclear fuel cycle facilities; Um estudo sobre o efeito domino em instalacoes do ciclo do combustivel nuclear

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    Bozzolan, Jean-Claude

    2006-07-01

    Accidents caused by domino effect are among the most severe accidents in the chemical and process industry. Although the destructive potential of these accidental scenarios is widely known, little attention has been paid to this problem in the technical literature and a complete methodology for quantitative assessment of domino accidents contribution to industrial risk is still lacking. The present study proposed a systematic procedure for the quantitative assessment of the risk caused by domino effect in chemical plants that are part of nuclear fuel cycle plants. This work is based on recent advances in the modeling of fire and explosion damage to process equipment due to different escalation vectors (heat radiation, overpressure and fragment projection). Available data from literature and specific vulnerability models derived for several categories of process equipment had been used in the present work. The proposed procedure is applied to a typical storage area of a reconversion plant situated in a complex that shelters other nuclear fuel cycle facilities. The top-events and escalation vectors are identified, their consequences estimated and credible domino scenarios selected on the basis of their frequencies. (author)

  8. Avaliação da tolerabilidade e do controle de ciclo de dois contraceptivos orais de baixa dose: estudo comparativo aberto Assessment of the tolerability and cycle control of two low-dose oral contraceptives: an open-label study

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    Edmund C. Baracat

    1998-06-01

    Full Text Available Realizou-se um estudo aberto comparativo em nove centros brasileiros para avaliar a tolerabilidade e o controle de ciclo obtido com o uso de dois contraceptivos orais de baixa dose contendo 20 mg etinilestradiol/75 mg gestodeno e 20 mg etinilestradiol/150 mg desogestrel, durante seis ciclos de tratamento. Foram selecionadas 167 mulheres saudáveis com vida sexual ativa (77 no grupo do gestodeno e 90 no grupo do desogestrel, das quais 138 completaram os seis ciclos de tratamento. Em um subgrupo de novas usuárias realizou-se também perfil lipídico e hemostático. Foram avaliados 867 ciclos no total. Ocorreu sangramento irregular em 4,6% dos ciclos com gestodeno e em 8,1% com desogestrel. A tolerabilidade a ambas preparações foi boa, mas houve significativamente mais náusea no grupo do desogestrel. O controle de ciclo foi bom com os dois contraceptivos, sendo que houve freqüência significativamente menor de sangramento irregular no grupo do gestodeno quando se leva em conta que todos os ciclos foram considerados. Não houve alterações clinicamente significativas no perfil hemostático. O perfil lipídico mostrou tendência a tornar-se mais favorável após seis ciclos de tratamento com as duas preparações. Não ocorreu alteração no peso médio das mulheres no grupo do gestodeno; no grupo do desogestrel houve aumento significativo no peso médio de aproximadamente 1 kg após seis meses de tratamento. A adesão ao tratamento foi boa com as duas preparações. Os resultados deste estudo mostram que preparações contendo baixa dose de gestodeno ou desogestrel associados a 20 mg de etinilestradiol são contraceptivos bem tolerados que permitem bom controle de ciclo, sem efeitos colaterais significantes.An open-label comparative study was conducted in nine centers in Brazil to evaluate the tolerability and cycle control of two low-dose oral contraceptives containing 20 mg ethynylestradiol/75 mg gestodene and 20 mg ethynylestradiol/150 mg

  9. Coyuntura económica y ciclos: el ciclo bursátil

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    Iglesia de la Pinta, Roberto de la

    2016-01-01

    Este proyecto crea un hilo conector que interioriza la coyuntura al ciclo económico y que enfrenta la evolución temporal de la actividad económica a la financiera. En un primer momento, se dan a conocer los propósitos que un análisis de coyuntura económica persigue, a la vez que se ofertan guías e instrumentos necesarios para su confección. En segunda instancia, se presentan las formas en que se manifiesta el ciclo económico así como las teorías que entienden su existencia como algo inseparab...

  10. Liquid-base cytology: a new method for oestral cycle study in wistar's rats Citologia de base líquida: um novo método para o estudo do ciclo estral em ratas Wistar

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    Rand Randall Martins

    2005-01-01

    Full Text Available OBJECTIVES: The objective of this study was the standardization of a collection technique and staining in liquid-base that allies the pratical and cytological wealth, making possible a larger reproductibility and microscopic easiness. METHODS: Female wistar rats (n=20 were submitted to the daily vaginal collection in saline and fastened washed (ether/alcohol and stained in suspension with a solution of Evans Blue 0.025%. The sample was pondered by centrifugation and observed under lens of 40 x. RESULTS: The stained smears allowed clear differentiation of the phases of hormonal cycle (diestrus, proestrus, estrus and metestrus; besides the differentiation of the cellular types in relation to its maturation degree having as parameters the cellular size, nucleus / cytoplasm relationship (NCR and ink reaction. The study demonstrated the existence of three basic cellular patterns: cells with low NCR, accentuated cyanophily and small size; cells with increment in NCR, cyanophilic loss and larger volume cytoplasmatic and without nuclei keratinization cells in squamous aspect. CONCLUSION: The staining of the material allowed, besides the cytological classification, the quantification possibility that would result in a perfected accompaniment of the cycle estrous.OBJETIVOS: O objetivo deste estudo foi à padronização de uma técnica de coleta e coloração em meio líquido que alie a praticidade e a riqueza citológica, possibilitando uma maior reprodutividade e facilidade microscópica. MÉTODOS: Ratas wistar (n=20 foram submetidas à coleta vaginal diária em salina e o lavado fixado (éter/álcool e corado em suspensão com solução de azul de Evans 0,025%. A amostra foi concentrada por centrifugação e observado sob objetiva de 40 x. RESULTADOS: Os esfregaços corados permitiram nítida diferenciação das fases do ciclo hormonal (diestro, proestro, estro e metaestro; além da diferenciação dos tipos celulares em relação ao seu grau de matura

  11. L’ipotesi del ciclo vitale, la politica fiscale e la previdenza sociale

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    Tullio Jappelli

    2005-06-01

    Full Text Available Il lavoro riassume le principali implicazioni dell’ipotesi del ciclo vitale per quanto riguarda il risparmio individuale e aggregato, la politica fiscale e la previdenza sociale, soffermandosi sui contributi più importanti di Modigliani su questi temi. Anche se non è facile conciliare alcuni risultati empirici recenti con l’ipotesi del ciclo vitale, soprattutto gli aspetti di inerzia, miopia e comportamento irrazionale documentati nella letteratura comportamentale, gli studi di Modigliani rappresentano ancora oggi la base di riferimento principale per studiare le decisioni dirisparmio individuali e per operare scelte di politica economica.

  12. A amamentação nos manuais escolares de estudo do meio do 1º ciclo do ensino básico La lactancia en los libros de texto escolares del Estudio del Medio del 1º ciclo de la educación básica Breastfeeding in Environmental Studies textbooks used in the first cycle of basic education

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    Dulce Maria Pereira Garcia Galvão

    2011-07-01

    Full Text Available Para conhecer como a amamentação é abordada às crianças do 1º Ciclo, e o que aprendem na escola sobre este tema, analisaram-se, do 1º ao 4º ano de escolaridade, 19 manuais escolares de Estudo do Meio, adoptados em 73 escolas públicas de seis agrupamentos de escolas da área educativa de Coimbra. Na análise dos conceitos transmitidos definiram-se, a priori, alguns considerados imprescindíveis para ensinar e explicar à criança noções básicas de amamentação. Apenas dois manuais do 3º ano incluíam, cada um, os conteúdos “Somos mamíferos. Alimentamo-nos das mamas das nossas mães após o nascimento” e “O natural é tomar leite materno logo depois do nascimento”. A análise dos manuais permitiu observar que existem diversas oportunidades de ensinar, esclarecer e ajudar a criança a aprender uma cultura da amamentação, pois este tema pode estar incluído em diversos capítulos das diferentes rubricas programáticas. No entanto, estas oportunidades são desperdiçadas e neste material didáctico várias imagens utilizadas promovem a alimentação artificial.Para conocer cómo se les presenta la lactancia a los niños del y lo que aprenden en la escuela sobre este tema, se analizaron, del 1º al 4º año de escolaridad, 19 libros de texto escolares del Estudio del Medio, adoptados en 73 escuelas públicas de seis grupos de escuelas del área educativa de Coimbra. En el análisis de los conceptos transmitidos se definieron, a priori, algunos considerados imprescindibles para enseñar y explicarle al niño nociones básicas de lactancia. Solo dos libros de texto del 3º año incluían, en cada caso, los contenidos “Somos mamíferos. Nos alimentamos del pecho de nuestras madres después de nacer” y “Lo natural es tomar leche materna después de haber nacido”. El análisis de los libros de texto permitió observar que existen diversas oportunidades de enseñar, aclarar e ayudar al niño a aprender una cultura de la

  13. Histomorphometric and functional studies of the rat thyroid throughout the estrous cycle Histomorfometria e função tireoidiana no ciclo estral da rata

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    R. Serakides

    2002-02-01

    Full Text Available The influence of the estrous cycle on the thyroid gland was studied. Twenty one five-to-seven-month-old Wistar female rats were divided according to the stage of the estrous cycle in two groups: metaestrus-diestrus and proestrus-estrus. After gross inspection, the thyroids were weighed, sampled, and processed for staining with hematoxilyn-eosin. Seric concentrations of total T4, free T4, total T3, TSH, progesterone, and estradiol were measured. The values of estradiol were significantly higher in the proestrus-estrus stage. However, no significant differences in the plasmatic concentrations of progesterone, free T4, total T4 and TSH throughout the cycle were found. The results of the morphometric study of the thyroid did not indicate any significant differences between the groups. These findings suggest that there is no thyreotrophic effect of estrogen during the estrous cycle in rats.

  14. Histomorphometric and functional studies of the rat thyroid throughout the estrous cycle Histomorfometria e função tireoidiana no ciclo estral da rata

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    R. Serakides; V.A. Nunes; E.F. Nascimento; G.V. Serra

    2002-01-01

    The influence of the estrous cycle on the thyroid gland was studied. Twenty one five-to-seven-month-old Wistar female rats were divided according to the stage of the estrous cycle in two groups: metaestrus-diestrus and proestrus-estrus. After gross inspection, the thyroids were weighed, sampled, and processed for staining with hematoxilyn-eosin. Seric concentrations of total T4, free T4, total T3, TSH, progesterone, and estradiol were measured. The values of estradiol were significantly highe...

  15. Ciclos peruanos, andinos y de Estados Unidos

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    Javier Iguíñiz Echeverría

    1997-12-01

    Full Text Available En este artículo hemos comparado las fluctuaciones de las economíasandinas entre sí durante 1950-1995 y la evolución cíclica de la economíaperuana y de Estados Unidos de Norteamérica entre 1929 y 1995. El resultadoprincipal de la comparación basada en la descomposición de las series por elmétodo determinístico y de Hodrick-Prescott, es que hasta 1981 los ciclosandinos están positiva y significativamente correlacionados entre sí con laexcepción de Venezuela. La sincronía con el ciclo de EE.UU. es mayor en elcaso de los países no petroleros del área, pero, en general, es menos robustaque la encontrada entre los países andinos.La correlación positiva y significativa entre países andinos y con EE.UU.desaparece en el período 1981-1995. La crisis de la deuda “desconecta” lastrayectorias de corto plazo. La correlación entre los ciclos de Perú y EE.UU.es positiva y significativa cuando se compara el período 1929-1981 y pierdesignificancia en el período 1981-1995.

  16. Fazendas paulistas: arquitetura rural no ciclo cafeeiro

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    Vladimir Benincasa

    2008-01-01

    Analisa a arquitetura rural do atual Estado de São Paulo durante o ciclo cafeeiro entre 1800 e a década de 1940, período marcado por grandes transformações na história brasileira. O enfoque é dado ao núcleo rural da fazenda cafeeira, investigando questões como: critérios para a escolha do sítio a ser implantado; o agenciamento e as inter-relações entre as edificações; a arquitetura e o uso dos diversos edifícios que o compõem; além de suas mudanças no tempo e no espaço. O estudo se vale de le...

  17. Study Links Psychiatric Disorders to Stroke Risk

    Science.gov (United States)

    ... fullstory_163750.html Study Links Psychiatric Disorders to Stroke Risk Mental health woes may trigger chronic fight- ... may be linked to a higher risk of stroke in the following weeks and months, new research ...

  18. Relação entre ciclo menstrual e planejamento dos treinos: um estudo de caso - DOI: 10.4025/actascihealthsci.v30i1.4381 The relation between the menstrual cycle and training schedule: a case study - DOI: 10.4025/actascihealthsci.v30i1.4381

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    Carlos Alexandre Molena Fernandes

    2008-07-01

    Full Text Available Este estudo de caso teve como objetivo verificar a relação do treinamento de tênis de campo com o ciclo menstrual em uma atleta com 17 anos de idade. O período de treinamento foi de 16 semanas. As avaliações motoras foram realizadas em dois momentos, no período de ovulação do ciclo menstrual da atleta investigada. Foram analisadas as capacidades motoras específicas ao tênis de campo: velocidade, potência muscular de membros superiores, potência muscular de membros inferiores e agilidade. Os resultados encontrados demonstram que houve melhora considerável em todas as variáveis. Sendo assim, sugere-se que um planejamento orientado, baseado no princípio da individualidade, poderá orientar cargas de treinos, buscando melhores resultados, entretanto são necessárias monitorações, em diferentes períodos do ciclo menstrual com uma população maior, na busca de respostas por demais fatores relacionados com a menstruação e exercício.This case study had as objective to verify the relation between tennis training and the menstrual cycle of a 17-year-old athlete. The training period lasted 16 weeks. Performance tests were carried out in two instances during the ovulation period of the menstrual cycle of the investigated athlete. Motor skills specific to tennis were analyzed: speed, arm muscle strength, leg muscle strength and agility. The results demonstrated a considerable improvement in all variables. Therefore, it is suggested that a guided plan, based of the principle of individuality, will be able to guide training loads and seek better results. However, monitoring is necessary in the different periods of the menstrual cycle, using a larger population sample, in the search for answers to other factors related to menstruation and exercise.

  19. Study of International Standards of Risk Management

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    Dykan Volodymyr L.

    2014-01-01

    Full Text Available The goal of the article lies in the study of existing international standards of risk management, an important factor of improvement of risk management in domestic corporations and enterprises and development of recommendations on application of international standards in Ukraine, in particular, within the framework of building corporate systems of risk management. The conducted study shows that approaches on organisation of the process of risk management, used in standards of risk management, are of general character and differ with the degree of detailing. Their undoubted value in development of risk management in Ukraine is identification of a general direction of building corporate systems of risk management in practice. The said approaches at the national and corporate levels of standardisation in Ukraine within the framework of building corporate systems of risk management would allow improvement of risk management in corporations and enterprises. The prospect of further studies of domestic specialists in the field of risk management is development of the domestic standard of risk management with consideration of modern domestic specific features of development of risk management in Ukraine and leading foreign experience.

  20. Autorrelatos do amor no ciclo vital adulto

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    José Augusto Evangelho Hernandez

    2015-07-01

    Full Text Available Esta pesquisa transversal comparou grupos de pessoas de diferentes faixas etárias, adultos jovens, maduros e maiores de 50 anos. Foram verificadas possíveis modificações do amor ao longo do ciclo vital adulto. Participaram 211 sujeitos de ambos os sexos, envolvidos em tipos variados de relações amorosas, que responderam à Escala Triangular do Amor de Sternberg. Os resultados da análise de variância multivariada mostraram interações significativas entre os componentes do amor e as faixas etárias e entre os componentes do amor e o sexo dos participantes. Análises univariadas revelaram diferenças significativas em intimidade entre as faixas etárias. Além disso, os níveis de paixão, intimidade e compromisso dos homens foram mais elevados do que os das mulheres. Estes resultados foram discutidos à luz da literatura que aborda a Teoria Triangular do Amor.

  1. Ciclos reais brasileiros em dois setores

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    Fabio Kanczuk

    2004-03-01

    Full Text Available Construímos um modelo de equilíbrio geral dinâmico de dois setores com o intuito de investigar o comportamento dos ciclos reais brasileiros. Quando os investimentos dos dois setores são agregados de acordo com uma Cobb-Douglas para formação de capital, o modelo é consistente com as volatilidades cíclicas dos componentes das contas nacionais e com a natureza contracíclica das exportações líquidas e do câmbio real. Caso a elasticidade de substituição entre o consumo de comercializáveis e de não comercializáveis seja baixa, o modelo também reproduz a volatilidade observada no câmbio real.We construct a two-sector dynamic general equilibrium model to investigate the behavior of the Brazilian business cycles. When investments from each sector are aggregated according to a Cobb-Douglas for capital formation, the model is consistent with the cyclical volatilities of national income components as well as with the countercyclical character of net exports and real exchange rates. If the elasticity of substitution between consumptions of tradeables and non-tradeables is low, the model can also reproduce the observed real exchange rates volatilities.

  2. Hybrid Risk Management Methodology: A Case Study

    Directory of Open Access Journals (Sweden)

    Jacky Siu-Lun Ting

    2009-10-01

    Full Text Available Risk management is a decision-making process involving considerations of political, social, economic and engineering factors with relevant risk assessments relating to a potential hazard. In the last decade, a number of risk management tools are introduced and employed to manage and minimize the uncertainty and threats realization to the organizations. However, the focus of these methodologies are different; in which companies need to adopt various risk management principles to visualize a full picture of the organizational risk level. Regarding to this, this paper presents a new approach of risk management that integrates Hierarchical Holographic Modeling (HHM, Enterprise Risk Management (ERM and Business Recovery Planning (BCP for identifying and assessing risks as well as managing the consequences of realized residual risks. To illustrate the procedures of the proposed methodology, a logistic company ABC Limited is chosen to serve as a case study Through applying HHM and ERM to investigate and assess the risk, ABC Limited can be better evaluated the potential risks and then took the responsive actions (e.g. BCP to handle the risks and crisis in near future.

  3. Juros reais e ciclos reais brasileiros

    Directory of Open Access Journals (Sweden)

    Fabio Kanczuk

    2002-01-01

    Full Text Available Este artigo apresenta um modelo de equilíbrio geral dinâmico, construído para estudar a relação quantitativa entre flutuações nas taxas de juros reais e os ciclos reais da economia brasileira. Quando as firmas estão sujeitas a restrições de capital de giro, o modelo é consistente com as volatilidades cíclicas dos componentes das contas nacionais e com a natureza contracíclica dos juros reais. Simulações com regras de Taylor alternativas indicam como as estimações econométricas da curva IS dinâmica estão sujeitas à crítica de Lucas. O artigo apresenta sugestões de como o modelo de metas inflacionárias atualmente utilizado pelo Bacen deveria ser modificado para incorporar os resultados encontrados.This paper presens a dynamic general equilibrium model to assess the quantitative relation between fluctuations in real interest rates and business cycles in the Brazilian economy. When firms are subject to working capital restrictions, the model is consistent with the cyclical volatilities of national income components as well as with the countercyclical character of real interest rates. Simulations with alternative Taylor rules indicate how econometric estimations of the dynamic IS curve are susceptible to the Lucas critique. The paper suggests how the inflation targeting model currently used by the Central Bank of Brazil should be transformed to incorporate its findings.

  4. Ciclos reais e política fiscal no Brasil

    Directory of Open Access Journals (Sweden)

    Caio Cesar Mussolini

    2012-03-01

    Full Text Available Neste artigo buscamos desenvolver um modelo de ciclos reais com governo e capital público, de maneira a estudar o efeito dos choques fiscais sobre o ciclo econômico e reproduzir os principais fatos estilizados da política fiscal no Brasil do pós-guerra (1950-2006. O modelo reproduz bem as principais características das variáveis fiscais ao longo do ciclo econômico, notadamente, uma volatilidade maior dos gastos públicos (consumo e investimento vis-à-vis os respectivos gastos privados e o caráter procíclico da política fiscal brasileira. Dentre as variáveis fiscais analisadas, a razão carga tributária/PIB é a que menos varia ao longo do ciclo econômico, porém, é a mais importante para explicar o ciclo do produto além da produtividade.

  5. Ciclos de los negocios en Colombia: el papel de la política de estabilización

    Directory of Open Access Journals (Sweden)

    Jorge Mario Uribe

    2016-03-01

    Full Text Available ste documento mide la sincronización entre las políticas de estabilización y el ciclo de los negocios en Colombia en el periodo comprendido entre marzo de 1990 y junio de 2013. Para la construcción de los ciclos se utiliza la metodología clásica y se construye un ciclo de referencia a partir de ciclos individuales de tres índices de actividad económica real. Con el fin de medir la sincronización entre el ciclo de negocios y los ciclos de las políticas fiscal y monetaria se utiliza el estadístico de Harding y Pagan (2006. Se concluye que durante el periodo de estudio las políticas de estabilización tienden a ser procíclicas (por el lado fiscal y acíclicas (por el lado monetario. En la literatura se conoce a este fenómeno como when it rains, it pours y es común que se presente en economías emergentes como la colombiana. This document measures the synchronization between the stabilization policy and the Colombian business cycle during the period March 1990 – June 2013. A classical methodology is used for the cycle construction and a reference cycle is constructed parting from three individual cycles of three real economic activity indicators. With the end of measuring the synchronization between the business cycle and the fiscal and monetary policy, the Harding and Pagan statistical analysis (2006 is used. It is concluded that for the period of time studied the stabilization policies tend to be pro-cyclic (for the fiscal case and counter-cyclic (for the monetary case. This phenomenon is known in literature as when it rains, it pours and it is common to see in economies such as the Colombian

  6. Risk Assessment Study for Storage Explosive

    Directory of Open Access Journals (Sweden)

    S. S. Azhar

    2006-01-01

    Full Text Available In Malaysia, there has been rapidly increasing usage in amount of explosives due to widely expansion in quarrying and mining industries. The explosives are usually stored in the storage where the safety precaution had given high attention. As the storage of large quantity of explosive can be hazardous to workers and nearby residents in the events of accidental denotation of explosives, a risk assessment study for storage explosive (magazine had been carried out. Risk assessment study had been conducted in Kimanis Quarry Sdn. Bhd, located in Sabah. Risk assessment study had been carried out with the identification of hazards and failure scenarios and estimation of the failure frequency of occurrence. Analysis of possible consequences of failure and the effects of blast waves due to the explosion was evaluated. The risk had been estimated in term of fatalities and eardrum rupture to the workers and public. The average individual voluntary risk for fatality to the workers at the quarry is calculated to be 5.75 x 10-6 per person per year, which is much lower than the acceptable level. Eardrum rupture risk calculated to be 3.15 x 10-6 per person per year for voluntary risk. There is no involuntary risk found for fatality but for eardrum rupture it was calculated to be 6.98 x 10-8 per person per year, as given by Asian Development Bank.

  7. Movimientos correctos a la velocidad correcta sobre los ciclos correctos

    Directory of Open Access Journals (Sweden)

    Jorge Enrique Mejía Q.

    2006-05-01

    Full Text Available El propósito del estudio fue explicar cómo una pequeña empresa colombiana compite en el mercado de telecomunicaciones de Estados Unidos. Esto fue posible usando el modelo de la Doble Hélice de Fine, que muestra los ciclos estructurales de cambios tecnológicos, sobre los que la compañía tuvo que tomar las decisiones estratégicas correctas para seguir la dinámica sectorial a la velocidad correcta. El estudio de caso consistió en una síntesis histórica sectorial y de la empresa, incluyendo hitos claves, después, la velocidad fue medida y finalmente una decisión fue recomendada para poder sobrevivir sobre el patrón de movimientos y cambios sectoriales. / The purpose of this study was to explain how a little Colombian company competes in the dynamic US telecomm market. It was possible by using Fine´s Double Helix Model that shows two structural cycles to explain technological movements, in each cycle, the company studied had to do the correct strategic decisions to follow the industrial dynamics at the right clockspeed. The case study consisted of an industrial and a company historical synthesis, including key issues, afterwards, clockspeed is measured and finally a decision is recommended to survive on the pattern of industrial changes and movements.

  8. Currículo en el nivel preescolar costarricense: El Ciclo Materno Infantil (CMI

    Directory of Open Access Journals (Sweden)

    Ana Lucía Chaves Álvarez

    2009-12-01

    Full Text Available

    Recibido 20 de abril de 2009 • Aprobado 14 de setiembre de 2009 • Corregido 15 de octubre de 2009

     

    Resumen. Este artículo aborda la conceptuación y la descripción del Ciclo Materno Infantil como parte del nivel de preescolar del sistema educativo formal costarricense. Con el propósito de tener una visión más amplia de este Ciclo, se hace un repaso por el concepto de currículo, así como de los elementos que lo conforman, y, luego, se detallan específicamente los aspectos relacionados con el currículo de preescolar costarricense del Ciclo Materno Infantil, tomando como punto de partida el Programa de Estudio que se elaboró para atender este Ciclo en el sistema educativo de Costa Rica.

     

    Abstract. The present article tackles the conceptualization and description of the Infantile Maternal Cycle as p The present article tackles the conceptualization and description of the Infantile Maternal Cycle as part of the preschool level of the Costa Rican educational system. With the intention of having a wider vision of this Cycle, a revision is done for the curriculum concept, as well as, for the elements that shape it, and then there is a detailed description of specific aspects related to the preschool Costa Rican curriculum of the Infantile Maternal Cycle, taking as a starting point the Program of Study that was designed to attend the above Cycle in the Costa Rican educational system.

  9. Efeito da laparotomia exploradora no ciclo estral em borregas corriedale

    OpenAIRE

    1989-01-01

    Cada uma de sete borregas Corriedale foi submetida a duas laparotomias exploradoras no período diestral de dois ciclos sucessivos, a partir do mês de fevereiro. A inspeção dos ovários, o intervalo entre estros e a prova de cristalização do muco cervical indicaram não ter havido interferência da intervenção no ciclo estral dos animais operados.     Seven Carriedale maiden ewes were laparotomized twice five to eight days after two successive oestruses during February and March. Ovarian cy...

  10. La teoria del ciclo vitale del risparmio di Modigliani cinquant’anni dopo

    Directory of Open Access Journals (Sweden)

    Mauro Baranzini

    2012-04-01

    Full Text Available In the early 50s Franco Modigliani and Richard Brumberg and Albert Ando, ​​formulated the life-cycle theory of consumption and saving, which has been a huge success and undisputed for at least three decades. However, since the early 80s the life-cycle theory has been criticized in an increasingly tight for at least four reasons. The first is the existence of a significant intergenerational transmission of wealth, due to factors exogenous to the model of the life cycle. The second reason is the increasing evidence that the rich continue to save a greater extent than the less fortunate, as, in fact, Keynes argued. The third reason is that there is increasing evidence, at least in Western Europe and Japan, young families, during twenty and thirty years of age, save a positive and growing share of their income, which arises in decided contrast to the original version of the life-cycle theory. Finally, a number of empirical studies have found that retirees dismiss a high proportion of their income. This requires a serious rethinking of the approach of the life-cycle theory, which affects both the economic analysis and economic policy. Nei primi anni ’50 Franco Modigliani, insieme a Richard Brumberg e ad Albert Ando, formulò la teoria del ciclo vitale del consumo e del risparmio, che ha riscosso un enorme e indiscusso successo per almeno tre decenni. Tuttavia, a partire dai primi anni ’80 la teoria del ciclo vitale è stata criticata in modo sempre più serrato, per almeno quattro ragioni. La prima consiste nell’esistenza di una significativa trasmissione intergenerazionale della ricchezza, da ricondurre a cause esogene al modello del ciclo vitale. La seconda ragione è rappresentata dalla crescente evidenza che i ricchi continuano a risparmiare in misura maggiore rispetto ai meno fortunati, come, in effetti, Keynes sosteneva. Il terzo motivo è che vi sono prove sempre più evidenti, almeno nell’Europa occidentale e in Giappone

  11. Coffee and cardiovascular risk; an epidemiological study

    NARCIS (Netherlands)

    A.A.A. Bak (Annette)

    1990-01-01

    textabstractThis thesis comprises several studies on the effect of coffee and caffeine on cardiovascular risk in general, and the effect on serum lipids, blood pressure and selected hemostatic variables in particular. The association between coffee use and cardiovascular morbidity and mortality was

  12. Expectativa y ciclo: hacia una dinámica keynesiana

    Directory of Open Access Journals (Sweden)

    García Molina Mario

    1991-06-01

    Full Text Available

    In chapter 17 of the General Theory, Keynes introduced the concept of the own-rates of interest in order to study a monetary economy of production, under an implicit assumption of equilibrium. This paper extends this concept for the analysis of a monetary economy in permanent disequilibrium and upon essential uncertainty. It is shown how the theories of liquidity preference and of finance are taken as complementary explanations. Differences between actual and expected own rates help to explain short term phenomena. and the behavior of capitalist along the business cycle. Depressions appear as a possibility which, in the case of ocurring it is necessary either state intervention or any other exogenous element to the same market in order to overcome them.

    En el capitulo 17 de la Teoría General, Keynes introduce el concepto de tasa propia de interés para estudiar una economía monetaria bajo un supuesto implícito de equilibrio. En este trabajo se aplica el mismo concepto al análisis de una economía monetaria en desequilibrio permanente y con una incertidumbre irreductible. Se muestra que las teorías de la preferencia por la liquidez y la de financiamiento constituyen explicaciones complementarias. Las diferencias entre tasas propias esperadas y realizadas ayudan a explicar los fenómenos de corto plazo y el comportamiento de los inversionistas a lo largo del ciclo de negocios. Las depresiones aparecen como una posibilidad que, en caso de ocurrir, no pueden ser superadas sin intervención del Estado o de otro elemento exógeno al mercado mismo.

  13. Deficiência das enzimas do ciclo de Krebs

    OpenAIRE

    2016-01-01

    Trabalho final de mestrado integrado em Medicina, apresentado á Faculdade de Medicina da Universidade de Coimbra Introdução A importância do ciclo dos ácidos tricarboxílicos ou ciclo de Krebs está associada à formação de equivalentes redutores para a produção de energia (ATP) pela fosforilação oxidativa, na mitocôndria. Também tem uma importante ligação com outras vias, fornecendo intermediários importantes para a biossíntese de várias moléculas, tais como ácidos gordos, ami...

  14. Studying risk factors associated with Human Leptospirosis

    Directory of Open Access Journals (Sweden)

    Ramachandra Kamath

    2014-01-01

    Full Text Available Background: Leptospirosis is one of the most under diagnosed and underreported disease in both developed and developing countries including India. It is established that environmental conditions and occupational habit of the individuals put them at risk of acquiring disease, which varies from community to community. Various seroprevalence studies across the world have documented emerging situation of this neglected tropical disease, but limited have probed to identify the risk factors, especially in India. Objectives: The objective of this study was to identify the environmental and occupational risk factors associated with the disease in Udupi District. Materials and Methods: This population-based case-control study was carried out in Udupi, a District in Southern India from April 2012 until August 2012. Udupi is considered to be endemic for Leptospirosis and reported 116 confirmed cases in the year 2011. Seventy of 116 laboratory confirmed cases and 140 sex matched neighborhood healthy controls participated in the study. A predesigned, semi-structured and validated questionnaire was used for data collection through house to house visit and observations were noted about environmental conditions. Univariate analysis followed by multivariate analysis (back ward conditional logistic regression was performed by using STATA version 9.2 (StataCorp, College Station, TX, USA to identify potential risk factors. Results: Occupational factors such as outdoor activities (matched odds ratio [OR] of 3.95, 95% confidence interval [CI]: 1.19-13.0, presence of cut or wound at body parts during work (matched OR: 4.88, CI: 1.83-13.02 and environmental factors such as contact with rodents through using the food materials ate by rat (matched OR: 4.29, CI: 1.45-12.73 and contact with soil or water contaminated with urine of rat (matched OR: 4.58, CI: 1.43-14.67 were the risk factors identified to be associated with disease. Conclusion: Leptospirosis is still

  15. Study On Machining Processing Technology Risk Control

    Institute of Scientific and Technical Information of China (English)

    Li Xiqing

    2015-01-01

    In the industrial production process,only to ful y guarantee the machining production safety, it can been ensured that the smooth completion of machining process.Under this back ground,in the machining production process,the machinery processing safety would been ful y concerned,several factors, which may lead to the problem of mechanical processing and production process,were analyzed,and the relevant control strategies were researched.In view of this situation,this paper wil specifical y combined with the machining process characteristics to study the machining process manufacturability risk control.

  16. Case studies in Bayesian microbial risk assessments

    Directory of Open Access Journals (Sweden)

    Turner Joanne

    2009-12-01

    Full Text Available Abstract Background The quantification of uncertainty and variability is a key component of quantitative risk analysis. Recent advances in Bayesian statistics make it ideal for integrating multiple sources of information, of different types and quality, and providing a realistic estimate of the combined uncertainty in the final risk estimates. Methods We present two case studies related to foodborne microbial risks. In the first, we combine models to describe the sequence of events resulting in illness from consumption of milk contaminated with VTEC O157. We used Monte Carlo simulation to propagate uncertainty in some of the inputs to computer models describing the farm and pasteurisation process. Resulting simulated contamination levels were then assigned to consumption events from a dietary survey. Finally we accounted for uncertainty in the dose-response relationship and uncertainty due to limited incidence data to derive uncertainty about yearly incidences of illness in young children. Options for altering the risk were considered by running the model with different hypothetical policy-driven exposure scenarios. In the second case study we illustrate an efficient Bayesian sensitivity analysis for identifying the most important parameters of a complex computer code that simulated VTEC O157 prevalence within a managed dairy herd. This was carried out in 2 stages, first to screen out the unimportant inputs, then to perform a more detailed analysis on the remaining inputs. The method works by building a Bayesian statistical approximation to the computer code using a number of known code input/output pairs (training runs. Results We estimated that the expected total number of children aged 1.5-4.5 who become ill due to VTEC O157 in milk is 8.6 per year, with 95% uncertainty interval (0,11.5. The most extreme policy we considered was banning on-farm pasteurisation of milk, which reduced the estimate to 6.4 with 95% interval (0,11. In the second

  17. Reynolds stress scaling in pipe flow turbulence—first results from CICLoPE

    Science.gov (United States)

    Örlü, R.; Fiorini, T.; Segalini, A.; Bellani, G.; Talamelli, A.; Alfredsson, P. H.

    2017-03-01

    This paper reports the first turbulence measurements performed in the Long Pipe Facility at the Center for International Cooperation in Long Pipe Experiments (CICLoPE). In particular, the Reynolds stress components obtained from a number of straight and boundary-layer-type single-wire and X-wire probes up to a friction Reynolds number of 3.8×104 are reported. In agreement with turbulent boundary-layer experiments as well as with results from the Superpipe, the present measurements show a clear logarithmic region in the streamwise variance profile, with a Townsend-Perry constant of A2≈1.26. The wall-normal variance profile exhibits a Reynolds-number-independent plateau, while the spanwise component was found to obey a logarithmic scaling over a much wider wall-normal distance than the other two components, with a slope that is nearly half of that of the Townsend-Perry constant, i.e. A2,w≈A2/2. The present results therefore provide strong support for the scaling of the Reynolds stress tensor based on the attached-eddy hypothesis. Intriguingly, the wall-normal and spanwise components exhibit higher amplitudes than in previous studies, and therefore call for follow-up studies in CICLoPE, as well as other large-scale facilities.

  18. Modelo global do ciclo biogeoquímico do carbono-enxofre

    OpenAIRE

    Cleyde Corrêa Roncaratti

    1995-01-01

    Os dois ciclos mais importantes nas reações de oxi-redução, no ambiente de superfície, são o do carbono e o do enxofre que fazem parte de um sistema maior que compreende a atmosfera, biosfera e litosfera sedimentar. Levando isso em conta, partimos de um modelo de simulação numérica do ciclo biogeoquímico global, para investigar o papel do sistema carbono-oxigênio-enxofre. A modelagem se baseia em estudos nos quais o ciclo do carbono é conjugado com o ciclo do enxofre, elaborada a partir dos p...

  19. Efeito da seleção no primeiro ciclo de postura para produção de ovos sobre o desempenho no segundo ciclo

    Directory of Open Access Journals (Sweden)

    Schmidt Gilberto Silber

    2004-01-01

    Full Text Available Utilizou-se uma população selecionada (CC e uma controle (CCc, para avaliar o efeito da seleção, no primeiro ciclo de postura, durante 5 gerações, para características produtivas, sobre o desempenho no segundo ciclo. Avaliou-se o peso corporal (PC na 16ª (PC16, 40ª (PC40, 75ª (PC75 e 111ª (PC111 semana, peso médio do ovo (PMO, idade à maturidade sexual (IMS, produção de ovos ave/dia (POAD da IMS até a 64ª semana, a idade de reinício da postura após a muda (RP, a POAD do RP até a 120ª semana , a relação altura x largura dos ovos (REL e a densidade (DENS. Exceto PC111 e REL, as demais características avaliadas no segundo ciclo apresentaram mudanças genéticas significativas decorrentes da seleção para as mesmas características no primeiro ciclo. Houve incremento na POAD e PC e redução na IMS no primeiro ciclo. No segundo ciclo, foram mantidas as diferenças entre CC e CCc, para as características POAD e IMS, indicando resposta correlacionada entre estas características no primeiro e segundo ciclo. Conclui-se que a seleção para aumento do desempenho produtivo das aves durante o primeiro ciclo de postura mostrou ser eficiente para elevar os níveis de produção no segundo ciclo.

  20. Morphological features and vascularization study of caprine cyclic corpus luteum Características morfológicas e estudo da vascularização do corpo lúteo cíclico de cabras ao longo do ciclo estral

    Directory of Open Access Journals (Sweden)

    Maria Tereza M. Miranda-Moura

    2010-04-01

    Full Text Available Corpus luteum is a temporary endocrine gland that regulates either the estrous cycle and pregnancy. It presents extreme dependency on the adequate blood supply. This work aims to evaluate goat corpus luteum (CL vascular density (VD over the estrous cycle. For that purpose, 20 females were submitted to estrus synchronization/ovulation treatment using a medroxyprogesterone intra-vaginal sponge as well as intramuscular (IM application of cloprostenol and equine chorionic gonadotrophine (eCG. After sponge removal, estrus was identified at about 72hs. Once treatment was over, female goats were then subdivided into 4 groups (n=5 each and slaughtered on days 2, 12, 16 and 22 after ovulation (p.o. Ovaries were collected, withdrawn and weighted. CL and ovaries had size and area recorded. Blood samples were collected and the plasma progesterone (P4 was measured through RIA commercial kits. The VD was 24.42±6.66, 36.26±5.61, 8.59±2.2 and 3.97±1.12 vessels/mm² for days 2, 12, 16 and 22 p.o, respectively. Progesterone plasma concentrations were 0.49±0.08, 2.63±0.66, 0.61±0.14 and 0.22±0.04ng/ml for days 2, 12, 16 e 22 p.o, respectively. Studied parameters were affected by the estrous cycle phase. Values greater than 12 p.o were observed. In the present work we observed that ovulation occurred predominantly in the right ovary (70% of the animals, which in turn presented bigger measures than the contra lateral one. There is a meaningful relationship between the weight and size of the ovary and these of CL (r=0.87, r=0.70, respectively, pO corpo lúteo é uma glândula endócrina temporária que regula tanto o ciclo estral quanto a prenhez, apresentando extrema dependência de aporte sanguíneo adequado. Objetivaram-se avaliar mudanças morfométricas dos ovários e densidade vascular (DV dos corpos lúteos (CL de cabras ao longo do ciclo estral (AOLC. Vinte animais foram submetidos ao tratamento para indução/sincronização do estro, usando esponjas

  1. Yeats, Cuchulain e la fine del ciclo

    Directory of Open Access Journals (Sweden)

    Dario Calimani

    2013-03-01

    Full Text Available In analysing two ‘Cuchulain plays’ by Yeats, this study highlights the central quality of modernism in On Baile’s Strand, where tragedy is deflated by farce and contaminated with low-mimetic style, and the full expression of despair is hindered by a Blind Man and a Fool, acting as spectators and providing an alternative view of existence. In The Death of Cuchulain the hero’s tragedy is revisited, thus haunting the final moments of his life. Yet again, Cuchulain is denied his tragic stature and is assigned a farcical death which diminishes his mythical figure. The ultimate stage of demythization is reached in Purgatory, a play with no Cuchulain, where an Old Man and a Boy reproduce the father-son struggle, with the former killing the latter. Yeats’s obsessive theme has come to an end. The annihilation of the Cuchulain myth and its central event, at the end of Yeats’s life, seems to be pointing to the end of all ideals in a final apocalypse devoid of any possible eternal return.

  2. Metas y valores situacionales en el ciclo de vida psicosocial

    OpenAIRE

    Di Grillo, Marcelo

    2014-01-01

    Partiendo de la teoría del ciclo vital de Erikson con su definición de las metas a lograr en cada etapa, se focalizan las etapas de la vida adulta del hombre. Los cambios en la vida cotidiana posmoderna, posterior a Erikson, ponen en tela de juicio la asociación entre edad y metas a cubrir. La vida líquida obliga a recomenzar la carrera, la familia, la acumulación de riqueza, la educación de los hijos a cualquier edad. La pregunta es los valores situacionales que la persona sostiene como orie...

  3. Ciclos límites en minirobots neurocontrolados

    OpenAIRE

    Jesús Alberto Delgado

    2011-01-01

    Este artículo presenta el análisis de estabilidad de un pequeño robot controlado con una red neuronal multicapa; por simplicidad, el robot contiene un sensor de posición y un motor. La función descriptiva de la red neuronal se utiliza para determinar los límites para los pesos de la red, con el fin de predecir ciclos límite y evitar oscilaciones del minirobot cuando se aproxima a obstáculos.

  4. Afrontamiento, resiliencia y bienestar a lo largo del ciclo vital

    OpenAIRE

    Mayordomo Rodriguez,Teresa

    2013-01-01

    El ser humano a lo largo del ciclo vital se enfrenta situaciones y sucesos para los que debe poner en marcha estrategias de afrontamiento que faciliten su adaptación y generen bienestar. La mayoría de los teóricos del afrontamiento (Carver, Scheier y Weintraub, 1989; Lazarus y Folkman, 1984; Moos, 1988; Moos y Billing, 1982), concuerdan en clasificar tres dominios generales de las estrategias según cómo éstas estén dirigidas a: la valoración (afrontamiento cognitivo), un intento de encontr...

  5. Funcionamento sexual e ciclo-de-vida em mulheres portuguesas

    OpenAIRE

    2006-01-01

    Dissertação de Mestrado em Psicopatologia e Psicologia Clínica O objectivo da presente investigação foi a avaliação do funcionamento sexual, da satisfação sexual, dos comportamentos sexuais, e da prevalência de dificuldades sexuais em mulheres portuguesas numa perspectiva de ciclo-de-vida. Optou-se por proceder à validação do índice de Funcionamento Sexual Feminino (FSFI; Rosen et al., 2000) e do índice de Satisfação Sexual (ISS; Hudson, Harrison & Crosscup, 1981). Recorreu-se a uma amostr...

  6. Antiepileptic drugs and risk of suicide: a nationwide study

    DEFF Research Database (Denmark)

    Olesen, Jonas Bjerring; Hansen, Peter Riis; Erdal, Jesper;

    2010-01-01

    Purpose Patients with epilepsy or psychiatric diseases have increased risk of suicide, but whether the risk is influenced by antiepileptic drug (AED) treatment is unclear. Studies have suggested that AEDs in general increase the risk of suicidal behaviour shortly after initiation. This study inve...

  7. Antiepileptic drugs and risk of suicide: a nationwide study

    DEFF Research Database (Denmark)

    Olesen, J.B.; Hansen, Peter Riis; Erdal, Jesper;

    2010-01-01

    Purpose Patients with epilepsy or psychiatric diseases have increased risk of suicide, but whether the risk is influenced by antiepileptic drug (AED) treatment is unclear. Studies have suggested that AEDs in general increase the risk of suicidal behaviour shortly after initiation. This study...

  8. Risk of cardiovascular disease? A qualitative study of risk interpretation among patients with high cholesterol

    OpenAIRE

    Kirkegaard, Pia; Edwards, Adrian; Risør, Mette Bech; Thomsen, Janus Laust

    2013-01-01

    Background Previous studies have shown the importance of paying attention to lay peoples’ interpretations of risk of disease, in order to explain health-related behavior. However, risk interpretations interplay with social context in complex ways. The objective was to explore how asymptomatic patients with high cholesterol interpret risk of cardiovascular disease. Methods Fourteen patients with high cholesterol and risk of cardiovascular disease were interviewed, and patterns across patient a...

  9. Bullying increased suicide risk: prospective study of Korean adolescents.

    Science.gov (United States)

    Kim, Young Shin; Leventhal, Bennett L; Koh, Yun-Joo; Boyce, W Thomas

    2009-01-01

    This study examines the independent impact of bullying on suicide risk. Bullying was assessed by peer nomination in a prospective study of 1,655 7th and 8th grade Korean students, and suicide by youth self-report. Odds Ratios (ORs) of bullying for suicidal risks were computed, controlling for other suicide risk factors. Victim-Perpetrators and female Victims at baseline showed increased risk for persistent suicidality (OR: 2.4-9.8). Male Incident Victims exhibited increased risk for suicidal behaviors and ideations (OR = 4.4, 3.6). Female Persistent Perpetrators exhibited increased risks for suicidal behaviors; male Incident Perpetrators had increased risk for suicidal ideations (OR = 2.7, 2.3). Baseline-only male Victim-Perpetrators showed increased risk for suicidal ideations. (OR = 6.4). Bullying independently increased suicide risks.

  10. Comparison of veterinary import risk analyses studies

    NARCIS (Netherlands)

    Vos-de Jong, de C.J.; Conraths, F.J.; Adkin, A.; Jones, E.M.; Hallgren, G.S.; Paisley, L.G.

    2011-01-01

    Twenty-two veterinary import risk analyses (IRAs) were audited: a) for inclusion of the main elements of risk analysis; b) between different types of IRAs; c) between reviewers' scores. No significant differences were detected between different types of IRAs, although quantitative IRAs and IRAs publ

  11. PYMES: Ciclo de Vida y Etapas de su Desarrollo

    Directory of Open Access Journals (Sweden)

    Juan Carlos Leiva Bonilla

    2013-02-01

    Full Text Available Apoyar a las micro, pequeñas y medianas empresas(mipymes es una forma de incrementar la competitividady con ello el desarrollo nacional. Uno de los principalesobstáculos que revierte este apoyo es la carencia de untrato individualizado para cada empresa considerando susparticularidades y grado de desarrollo. Buscando atenuar lo anterior se diseñó un modelo bajoel cual se puedan clasificar a las empresas, según su estadoevolutivo en diversas variables, y con ello “individualizar”cada organización. El modelo se construyó en torno a siete variables: *Rol del emprendedor. *Enfoque de la gestión. *Rol de los recursos humanos. *Estructura. *Sistemas (operativos y directivos. *Ventas e indicadores financieros. *Infraestructura. Tomando en cuenta las citadas variables y su senderoevolutivo, la empresa podría ubicarse en las siguientesetapas: 1. La empresa surge y pone a prueba su oferta en elmercado. 2. La empresa percibe que su oferta es aceptada y empiezaa crecer. 3. La empresa alcanza un crecimiento importante y debeprofesionalizarse. 4. La empresa se consolida mediante profesionalización ycomo organización. 5. La empresa empieza a mostrar signos de envejecimiento. Adicionalmente se efectuó un análisis de los temas yenfoques de gestión que debería implementar una empresaacorde a su ubicación en el de ciclo de vida propuesto. Lacomprobación empírica y el estudio de campo se efectuaronen 55 mipymes registradas en la base de datos del Programade Emprendedores del ITCR.   ABSTRACT The support the micro, small and medium companies(smes is a way to increase their competitiveness and thusnational development. One of the main obstacles that hinderthis support is the lack of an individualized treatment foreach company that considers its particularities and degree ofdevelopment. Looking to attenuate the above a model was designedunder which it is possible to classify the companies, accordingto their evolutionary state by diverse

  12. New technologies for offshore wildlife risk studies

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, Caleb

    2011-07-01

    Full text: Two research initiatives by Pandion Systems, funded by the US Bureau of Ocean Energy Management, Regulation, and Enforcement (BOEMRE), are addressing the enormous challenges of conducting offshore wind-wildlife risk/impact studies by providing new wildlife sensing technologies that surmount some of the limitations of previous techniques. Both initiatives rest on the shoulders of pioneering European studies and experience. One entails the development of a remote-operating acoustic/thermographic detector. This device, designed with input from the Danish National Environmental Research Institute (NERI) and Cornell Laboratory of Ornithology (CLO), will provide species-specific occurrence data, as well as flight altitude estimation, for vocalizing flying wildlife that flies within a detection beam that corresponds roughly to the rotor swept zone of a single, commercial marine wind turbine. While the detection beam is small and limitations exist for silently flying animals, this device will be capable of providing information on bats and on federally-listed bird species that has been difficult or impossible to achieve with other methods. A preliminary version of this device was developed in 2009-2010 in a BOEMRE-funded pilot study, and a sea-worthy device is currently being developed, scheduled for initial deployment on the US Atlantic Outer Continental Shelf (AOCS) in summer, 2011. A second initiative is targeted at developing a high-definition aerial survey protocol capable of providing a safe, cost-effective, reproducible snapshot of bird, marine mammal, and sea turtle distribution on the entire AOCS. This research, being conducted with a team of technologists and biologists including scientists from the British Trust for Ornithology (BTO), entails conducting a series of pilot experiments in spring, 2011 with a variety of different aircraft, cameras, flight altitudes, and image resolutions, to determine optimum protocols for the large-scale surveys. Both of

  13. RISK COMMUNICATION IN ACTION: ENVIRONMENTAL CASE STUDIES

    Science.gov (United States)

    This handbook discusses a variety of data visualization and data interpretation tools that municipal, state and federal government agencies and others hve successfully used in environmental risk communication programs. The handbook presents a variety of tools used by several diff...

  14. Study of the scenarios for the Cycle 12 of the Unit 1 of the CNLV; Estudio de escenarios para el ciclo 12 de la Unidad 1 de la CNLV

    Energy Technology Data Exchange (ETDEWEB)

    Castillo, A.; Ortiz, J.J.; Montes, J.L.; Perusquia, R. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)]. e-mail: jacm@nuclear.inin.mx

    2005-07-01

    In this work the preliminary results of a study of scenarios of it loads of fuel and operation of the Cycle 12 of the Unit 1 of the Laguna Verde power station are presented. Based on the Plan of Energy Use (PUE) for this cycle, they were studied different possibilities, with the idea to satisfy the energy demand under sure performance of the reactor. In this work were contemplated similar fuel assemblies to those that are using at the moment in the Cycle 11 of that unit. The reload proposals using the Haling principle and patterns of control bars with the intelligent technique not exhaustive well-known as taboo search are analyzed. The simulator Cm-Presto was used to evaluate the scenarios. This study even continuous analyzing different options and improving the results. (Author)

  15. Epidemiological study of the effects of nuclear and fuel cycle facilities on the health of the neighbouring populations; Estudio epidemiologico del efecto de las instalaciones nucleares y del ciclo sobre la salud de las poblaciones vecinas

    Energy Technology Data Exchange (ETDEWEB)

    Bernal, A.; Lentijo, J. C.; Lopez-Abente, G.; Pollan, M.; Ramos, M. R.; Rodriguez, M.; Tello, O.; Urbano, I.

    2010-07-01

    The Carlos III Health Institute and the Nuclear Safety Council, signed an agreement for the performance of an epidemiological study to investigate the possible effects of exposure to ionising radiations on the health of populations living in the vicinity of nuclear and radioactive facilities involved in the nuclear fuel cycle. (Author)

  16. Corpos e ciclos da vida sanumá-yanomami

    Directory of Open Access Journals (Sweden)

    Sílvia Guimarães

    2010-12-01

    Full Text Available Esta etnografia sobre os Sanumá, subgrupo yanomami do alto rio Auaris, estado de Roraima, explora aspectos centrais de sua vasta e complexa cosmologia. Discute a noção de corpo e os ciclos de vida onde estados especiais devem ser observados no processo de construção da pessoa.This ethnography focuses on the Sanumá, a Yanomami subgroup located on the upper Auaris River, in the northernmost state of Roraima in Brazil. It explores central aspects of their vast and complex cosmology by discussing the concept of body and life cycles where special states related with the construction of the person must be observed.

  17. Ciclo Hápticos: Para Quinteto de Sopros

    Directory of Open Access Journals (Sweden)

    Jorge Luiz de Lima Santos

    2016-06-01

    Full Text Available Memorial e partitura de Ciclo Hápticos, escrita em 2014 para quinteto de sopros. O memorial descreve brevemente as ferramentas metodológicas empregadas para o planejamento e criação da obra. De um lado, para produção do material melódico-harmônico foi empregado o Sistema-Gr de composição musical, desenvolvido por Carlos Almada (2014. Do outro lado, para organização formal, utilizamos o software Partitions - que faz parte do conjunto de programas do Parsemat, elaborado por Pauxy Gentil-Nunes (2009 – o qual informa o conjunto total de possibilidades de partições de um dado número.

  18. ESTUDIO DEL BULLYING EN EL CICLO SUPERIOR DE PRIMARIA

    Directory of Open Access Journals (Sweden)

    Rosario Ruiz Arroyo

    2015-01-01

    Full Text Available Nuestra investigación trata el fenómeno del bullying en el ciclo superior de primaria. Para llevarla a cabo, hemos elaborado un cuestionario ad hoc a partir de una revisión bibliográfica de diferentes investigaciones en las que se han utilizado varios instrumentos, pruebas, cuestionarios... Este instrumento nos ha servido para analizar diferentes temas: la percepción que tienen los niños de ciclo superior sobre el bullying, en qué escenarios del centro escolar se producen más estos comportamientos, los diferentes tipos de bullying (físico, verbal y exclusión social y cuáles se producen más a menudo y analizar las respuestas que nos dan los alumnos en función del género y del curso (5.º y 6.º. Los resultados que hemos obtenido muestran, entre otras cosas: que en los niños se da más el bullying físico, mientras que en las niñas predomina el de tipo verbal y exclusión social; que la única diferencia según el curso es que en 6.º curso se da más exclusión social que en 5.º curso; y que donde se producen más conductas de bullying es en el patio, seguido del aula cuando no se encuentra el docente. Finalmente, partiendo de los resultados obtenidos, hemos elaborado unas propuestas de actuación psicopedagógicas para mejorar la convivencia en la escuela y otros espacios educativos.

  19. Behavior of uranium isotopes along a tidal cycle in a study affected by acid mine drainage; Comportamiento de los isotopos de uranio a lo largo de un ciclo mareal en un estuario afectado por denaje acido de minas

    Energy Technology Data Exchange (ETDEWEB)

    Hierro, A.; Martin, J. e.; Olias, M.; Garcia, C.; Bolivar, J. P.

    2013-07-01

    The Tinto and Odiel rivers converge in an estuarine system known as the Ria de Huelva, which is an ecosystem of great interest, conditioned by hydrochemical facts. The main objective of this study was to analyze the behavior of uranium isotopes in the waters of the Red River estuary in a tidal cycle under hydrochemical conditions of high gradients of salinity and pH generated by the acidic waters of the Rio Tinto and seawater. (Author)

  20. Liquid-base cytology: a new method for oestral cycle study in wistar's rats Citologia de base líquida: um novo método para o estudo do ciclo estral em ratas Wistar

    OpenAIRE

    Rand Randall Martins; Ney Moura Lemos Pereira; Telma Maria Araújo Silva

    2005-01-01

    OBJECTIVES: The objective of this study was the standardization of a collection technique and staining in liquid-base that allies the pratical and cytological wealth, making possible a larger reproductibility and microscopic easiness. METHODS: Female wistar rats (n=20) were submitted to the daily vaginal collection in saline and fastened washed (ether/alcohol) and stained in suspension with a solution of Evans Blue 0.025%. The sample was pondered by centrifugation and observed under lens of 4...

  1. Life cycle assessment and product category rules for the construction sector. The floor and wall tiles sector case study; Analisis de ciclo de vida y reglas de categoria de producto en la construccion. El caso de las baldosas ceramicas

    Energy Technology Data Exchange (ETDEWEB)

    Benveniste, G.; Gazulla, C.; Fullana, P.; Celades, I.; Ros, T.; Zaera, V.; Godes, B.

    2011-07-01

    This paper illustrates the Life Cycle Analysis (LCA) activities performed during the preparation of the Spanish Product Category Rules (PCR) relative to the construction sector. Specifically, the study presents the results obtained from the life cycle analysis of the floor and wall tile sector, which served as the basis for the drafting of the PCR required for the definition of Environmental Product Declarations (EPD). More than 50 Spanish companies in the ceramic tile sector participated in the study, providing inventory data on the manufacture of their products. Additionally, bibliographic information and the GaBi 4 software database by PE International were used to complete background and generic data, such as those related to energy and transportation processes. EPDs are voluntary declarations based on LCA studies that permit the disclosure and dissemination of environmental information quantified over the life cycle of a product. The definition of PCRs for ceramic tiles was performed in accordance to the UNE EN ISO 14025 and ISO 21930 standards and they have been submitted to industries and professional association public consultations. PCRs have been developed in the context of the DAPc program (promoted by the Catalan Government and CAATEEB) and represents the first eco labelling activity for building products in Spain. (Author) 18 refs.

  2. Study on the Credit Risk in Societies with Agricultural Profile

    Directory of Open Access Journals (Sweden)

    Jenica POPESCU

    2015-09-01

    Full Text Available The credit risk is one of the most important risks the banks face in their daily work and it has a direct impact on bank performance. In the current context, a bank has available a variety of options to determine capital requirements, to decrease the credit risk. This study aims to analyze the correlation of the main indicators of creditworthiness of firms and the credit risk, that a bank will take giving credit to these firms.

  3. Nível de aderência dos artefatos de contabilidade gerencial sob a perspectiva do ciclo de vida organizacional: um estudo de caso = Adherence level of managerial accounting tools in the perspective of organizational life cycle: a case study

    Directory of Open Access Journals (Sweden)

    Tatiane Antonovz

    2010-05-01

    Full Text Available O estudo demonstra a evolução do uso dos artefatos de contabilidade gerencial sob a perspectiva dociclo de vida organizacional, investigando de acordo com o modelo delineado por Miller e Friesen(1984, que verifica a evolução da entidade, desde o nascimento até seu declínio. O modelo foiconfirmado pelo trabalho de Moores e Yuen (2001, que se baseou no estudo de Miller e Friensen(1984 para verificar como a evolução dentro deste modelo interfere no uso dos artefatos dacontabilidade gerencial. Quanto aos procedimentos metodológicos, utiliza-se de um estudo de casoaplicado em uma indústria de confecções do Noroeste do Paraná, conhecida como pólo industrialnessa área. Os achados do estudo evidenciam que há uma relação direta da evolução da entidade e oefetivo uso dos artefatos disponíveis, mas que nem sempre o estágio de vida em que esta se encontraconfirma tal situação, ou seja, não há necessariamente uma evolução do uso dos artefatos aliados àevolução da entidade. O trabalho pode confirmar a posição da empresa com relação ao modeloescolhido, porém foi verificado que não necessariamente todos os artefatos de contabilidade gerencialevoluíram conforme o modelo de Moores e Yuen (2001.This study aimed to demonstrate the evolution of the use of Management Accounting tools from theperspective of the organizational life cycle, by investigating the model outlined by Miller and Friesen(1984, based on the evolution of the human body, from birth to their decline, interferes the use ofthese tools. The model was confirmed by the work of Moores and Yuen (2001, which was based onthe study of Management Accounting, and the understanding of the evolution of entities. Using thetechnique of case study, justified as the most appropriate to describe a managerial position and capable to shows a real situation. The organization chosen is an industry of clothing the Northwest sideof Paraná, known as industrial pole in the area. The

  4. El ciclo del nitrógeno, propuesta para ciclo tres de educación media rural

    OpenAIRE

    Luengas Caicedo, Nidia Nelly

    2014-01-01

    El ciclo del nitrógeno representa un complejo sistema que conecta procesos biológicos, geológicos, químicos y físicos, y sirve como modelo para ilustrar las interacciones entre biósfera, atmósfera, geósfera e hidrósfera, todo ello mediado con una combinación de fenómenos cíclicos en unos casos, lineales en otros, reversibles e irreversibles. La apropiación por parte de los estudiantes de los conceptos básicos alrededor de este tema es fundamental para alcanzar la posterior comprensión de las ...

  5. Adolescent Risk Behaviors and Religion: Findings from a National Study

    Science.gov (United States)

    Sinha, Jill W.; Cnaan, Ram A.; Gelles, Richard J.

    2007-01-01

    Too few studies have assessed the relationship between youth risk behaviors and religiosity using measures which captured the varied extent to which youth are engaged in religion. This study applied three measures of religiosity and risk behaviors. In addition, this study ascertained information about youths' participation in religious activities…

  6. Emulsiones tipo crema preparadas a base de leche de soja 3: Efecto de ciclos de temperatura

    Directory of Open Access Journals (Sweden)

    Wagner, Jorge R.

    2005-09-01

    Full Text Available In this work, the effect of temperature cycling on emulsions formulated with reconstituted soy milk, sunflower oil and high melting point milk fat was analysed. The emulsions were prepared at 60 ºC , stored at 4 ºC (3 h, warmed at 40 ºC or 50 ºC (30 min and afterwards recooled at 4 ºC (2h. Although solid fat content of emulsions did not raised after tempering at 40 ºC , increase of G' and G'' was observed only in those formulated with 40 % lipid phase. This phenomenon was attributed to droplet aggregation due to partial melting, recrystallization and reordering of fat crystals in oil droplets. The main droplet destabilization mechanism was the partial coalescence; it was corroborated by nuclear magnetic resonance, differential scanning calorimetry and droplet size distribution studies. On the other hand, the consistency of 20 % of lipid phase emulsion did not increased. Low droplet concentration disfavoured the partial coalescence of droplets. Similar assays on cream at 40 ºC and cream-like soy milk emulsions at 50 ºC , did not show rheological modifications, due to almost total melting of milk fat during tempering.En este trabajo se analizó el efecto de ciclos calentamiento-enfriamiento sobre cremas preparadas a 60 ºC con leche de soja en polvo reconstituida, aceite de girasol y grasa láctea y almacenadas posteriormente a 4 °C durante 3 horas. Los ciclos consistieron en un calentamiento a 40 °C o 50 °C (30 min seguido de un re-enfriamiento a 4 °C (2 horas. En los ensayos realizados sobre cremas formuladas con 40% de fase lipídica se observó un aumento de los valores de G' y G'' después del ciclo 40 °C- 4 °C , a pesar de no haberse observado un aumento en el contenido de grasa sólida. Estos resultados se atribuyen a la formación de agregados de gotas inducida por la fusión parcial, reordenamiento y recristalización de la grasa láctea en las gotas. Estudios de resonancia magnética nuclear de

  7. Ciclos clássicos num ambiente de racionalidade limitada

    Directory of Open Access Journals (Sweden)

    Jaylson Jair da Silveira

    2003-12-01

    Full Text Available O presente trabalho toma como ponto de partida o modelo macrodinâmico de Richard M. Goodwin, apresentado no clássico artigo “A Growth Cycle” (1967. Neste modelo a interação entre distribuição de renda e acumulação de capital gera um ciclo de crescimento que oscila em torno de uma trajetória de crescimento equilibrado. O objetivo do presente trabalho é investigar a possibilidade de existência de ciclos goodwinianos com heterogeneidade de salários e de taxas de lucro. Essa análise é realizada considerando o processo de concorrência entre trabalhadores num ambiente de racionalidade limitada. Para formalizar o processo de concorrência entre trabalhadores foram utilizados dois recursos: (i a “alegoria das ilhas”, que tem sido amplamente adotada na macroeconomia moderna, a fim de apreender situações de informação imperfeita; e (ii os instrumentos analíticos desenvolvidos pela teoria dos jogos evolucionários aplicada a ambientes sociais. O modelo construído combina o modelo de Goodwin com uma formalização estilizada do fluxo de trabalho como um processo de imitação num ambiente de racionalidade limitada (dinâmica de replicação num contexto social. Neste modelo demonstra-se a possibilidade de o sistema econômico não convergir para um estado de equilíbrio de longo prazo e a possibilidade do sistema econômico convergir para um ciclo goodwiniano caracterizado por heterogeneidade de salários e de taxas de lucro.This paper starts from the macrodynamical model developed by Richard M. Goodwin, which was first shown in the seminal paper “A Growth Cycle” (Goodwin, 1967. In this model it was described an interaction between income-distribution and capital accumulation that generates a growth cycle swinging along a balanced growth path. The objective of this work is to investigate the possibility of existence of goodwinian cycles with heterogeneity in wage and in profit rates. This task is carried out considering the

  8. Correlational Study of Risk Management and Information Technology Project Success

    Science.gov (United States)

    Gillespie, Seth J.

    2014-01-01

    Many IT projects fail despite the best efforts to keep these projects within budget, schedule, and scope. Few studies have looked at the effect of project risk management tools and techniques on project success. The primary focus of this study was to examine the extent to which utilization of project risk management processes influence project…

  9. Review of studies related to uncertainty in risk analsis

    Energy Technology Data Exchange (ETDEWEB)

    Rish, W.R.; Marnicio, R.J.

    1988-08-01

    The Environmental Protection Agency's Office of Radiation Programs (ORP) is responsible for regulating on a national level the risks associated with technological sources of ionizing radiation in the environment. A critical activity of the ORP is analyzing and evaluating risk. The ORP believes that the analysis of uncertainty should be an integral part of any risk assessment; therefore, the ORP has initiated a project to develop framework for the treatment of uncertainty in risk analysis. Summaries of recent studies done in five areas of study are presented.

  10. La inversión y el ciclo económico

    OpenAIRE

    Llorca Marco, Adrián

    2016-01-01

    La inversión es un componente clave, no en el crecimiento económico a largo plazo, sino en la explicación del ciclo económico. Para comprender este importante fenómeno es fundamental indagar en el comportamiento de la inversión, sus relaciones con el ciclo y las causas que determinan sus fluctuaciones.

  11. Risk perception, experience, and objective risk: a cross-national study with European emergency survivors.

    Science.gov (United States)

    Knuth, Daniela; Kehl, Doris; Hulse, Lynn; Schmidt, Silke

    2014-07-01

    Understanding public risk perceptions and their underlying processes is important in order to learn more about the way people interpret and respond to hazardous emergency events. Direct experience with an involuntary hazard has been found to heighten the perceived risk of experiencing the same hazard and its consequences in the future, but it remains unclear if cross-over effects are possible (i.e., experience with one hazard influencing perceived risk for other hazards also). Furthermore, the impact of objective risk and country of residence on perceived risk is not well understood. As part of the BeSeCu (Behavior, Security, and Culture) Project, a sample of 1,045 survivors of emergencies from seven European countries (i.e., Germany, the Czech Republic, Poland, Sweden, Spain, Turkey, and Italy) was drawn. Results revealed heightened perceived risk for emergency events (i.e., domestic and public fires, earthquakes, floods, and terrorist attacks) when the event had been experienced previously plus some evidence of cross-over effects, although these effects were not so strong. The largest country differences in perceived risk were observed for earthquakes, but this effect was significantly reduced by taking into account the objective earthquake risk. For fires, floods, terrorist attacks, and traffic accidents, only small country differences in perceived risk were found. Further studies including a larger number of countries are welcomed.

  12. COMOVIMIENTO REGIONAL DEL EMPLEO DURANTE EL CICLO ECONÓMICOEN MÉXICO

    Directory of Open Access Journals (Sweden)

    Marcelo Delajara

    2011-01-01

    Full Text Available Determinamos el grado de comovimiento del empleo durante el ciclo económico entre las regiones de México mediante un análisis de la covarianza de las perturbaciones en los ciclos del empleo regional entre julio de 1997 y octubre de 2009. El empleo se mide por el número de trabajadores permanentes asegurados en el Instituto Mexicano del Seguro Social. La descomposición en tendencia y ciclo y la matriz de varianza-covarianza de las perturbaciones en los ciclos del empleo regional se obtienen de la estimación —por el método de espacio de estados— de un modelo estructural multivariado de las series de empleo. Encontramos que, exceptuando a unas pocas regiones, el comovimiento del empleo es alto y que la varianza de las perturbaciones en los ciclos regionales está asociada mayormente con las fluctuaciones del empleo nacional. Sin embargo, no encontramos pruebas de un ciclo común subyacente, por lo que el comovimiento del empleo tendría su origen en la propagación interregional de choques específicos.

  13. Sobre el ciclo maya de 819 días

    Directory of Open Access Journals (Sweden)

    Huberto Quiñones Garza

    2011-01-01

    Full Text Available Algunos autores consideran que los mayas manejaban un ciclo de 819 días, que habría tenido un carácter mágico o ritual, sin descartar alguna manifestación astrológica o astronómica. Un enfoque que no ha sido tomado en cuenta hasta hoy, es el puramente aritmético, el posible interés del sacerdocio maya en este número como tal. Se especula aquí que el número 819 está relacionado con el valor de TT, además de la probable vinculación que esta cifra podría guardar con sus sistemas numérico y calendárico. Dos situaciones se vislumbran como importantes contribuciones, el planteamiento epistemológico implícito y los resultados obtenidos como información básica para futuras investigaciones dentro de la etnomatemática y la antropología.

  14. Franco Modigliani e la teoria del ciclo vitale del consumo

    Directory of Open Access Journals (Sweden)

    Angus Deaton

    2005-06-01

    Full Text Available Nei primi anni ’50, Franco Modigliani e il suo studente Richard Brumberg elaborarono una teoria della spesa fondata sull’idea che gli individui effettuano scelte intelligenti su quanto desiderano spendere a ogni età, con il solo limite delle risorse disponibili nel corso della loro vita. Attraverso l’accumulo e il decumulo delle attività, chi lavora può provvedere alla propriapensione e, più in generale, può adattare i propri modelli di consumo alle esigenze che sipresentano alle diverse età, indipendentemente dal reddito disponibile in ogni momento della suavita. Questa semplice teoria conduce a previsioni rilevanti e non scontate per l’economia nel suo complesso, ad esempio che il risparmio nazionale dipende dal tasso di crescita del reddito nazionale e non dal suo livello, e che esiste una semplice relazione tra il livello della ricchezza nelsistema economico e la lunghezza del periodo trascorso in pensione. Tali previsioni, non verificabili negli anni ’50, hanno trovato considerevole sostegno empirico in successivi lavori di Modigliani e di altri ricercatori. Sebbene nel corso degli anni la teoria del consumo abbia subitonumerosi attacchi, i più recenti dei quali mossi da una coalizione di psicologi ed economisti,l’ipotesi del ciclo vitale rimane una parte essenziale del pensiero degli economisti.

  15. Updating risk prediction tools: a case study in prostate cancer.

    Science.gov (United States)

    Ankerst, Donna P; Koniarski, Tim; Liang, Yuanyuan; Leach, Robin J; Feng, Ziding; Sanda, Martin G; Partin, Alan W; Chan, Daniel W; Kagan, Jacob; Sokoll, Lori; Wei, John T; Thompson, Ian M

    2012-01-01

    Online risk prediction tools for common cancers are now easily accessible and widely used by patients and doctors for informed decision-making concerning screening and diagnosis. A practical problem is as cancer research moves forward and new biomarkers and risk factors are discovered, there is a need to update the risk algorithms to include them. Typically, the new markers and risk factors cannot be retrospectively measured on the same study participants used to develop the original prediction tool, necessitating the merging of a separate study of different participants, which may be much smaller in sample size and of a different design. Validation of the updated tool on a third independent data set is warranted before the updated tool can go online. This article reports on the application of Bayes rule for updating risk prediction tools to include a set of biomarkers measured in an external study to the original study used to develop the risk prediction tool. The procedure is illustrated in the context of updating the online Prostate Cancer Prevention Trial Risk Calculator to incorporate the new markers %freePSA and [-2]proPSA measured on an external case-control study performed in Texas, U.S.. Recent state-of-the art methods in validation of risk prediction tools and evaluation of the improvement of updated to original tools are implemented using an external validation set provided by the U.S. Early Detection Research Network.

  16. The study of risk in pulmonary arterial hypertension

    Directory of Open Access Journals (Sweden)

    Gerald Simonneau

    2012-09-01

    Full Text Available A growing body of published evidence exists on the risk factors for disease progression in pulmonary arterial hypertension (PAH. The Scientific Steering Committee for the Study of Risk in PAH was established to bring together leading clinical and statistical experts in PAH and risk modelling, for the purpose of advancing the understanding of the risk of development and progression of PAH. Herein, we discuss the impact of this information on three key areas: 1 clinical decision-making; 2 policy and reimbursement; and 3 future trials and research.

  17. Caffeine and the risk of hip fracture: the Framingham Study.

    Science.gov (United States)

    Kiel, D P; Felson, D T; Hannan, M T; Anderson, J J; Wilson, P W

    1990-10-01

    Caffeine increases urinary calcium output and has been implicated as a risk factor for osteoporosis. The authors examined the effect of caffeine on hip fracture risk in 3,170 individuals attending the 12th (1971-1973) Framingham Study examination. Coffee and tea consumption, age, Framingham examination number, weight, smoking, alcohol consumption, and estrogen use were used to evaluate hip fracture risk according to caffeine intake. Hip fractures occurred in 135 subjects during 12 years of follow-up. Fracture risk over each 2-year period increased with increasing caffeine intake (one cup of coffee = one unit of caffeine, one cup of tea = 1/2 unit of caffeine). For intake of 1.5-2.0 units per day, the adjusted relative risk (RR) of fracture was not significantly elevated compared with intake of one or less units per day. Consumption of greater than or equal to 2.5 units per day significantly increased the risk of fracture. Overall, intake of greater than two cups of coffee per day (four cups of tea) increased the risk of fracture. In summary, hip fracture risk was modestly increased with heavy caffeine use, but not for intake equivalent to one cup of coffee per day. Since caffeine use may be associated with other behaviors that are, themselves, risk factors for fracture, the association may be indirect. Further studies should be performed to confirm these findings.

  18. Estudo prospectivo comparativo dos ciclos de ultra-som 14% e 67% do WhiteStarTM na cirurgia de catarata por facoemulsificação com a técnica " nuclear preslice" Comparative prospective study of 14% and 67% duty cycles of the ultrasound power with WhiteStarTM in the phacoemulsification cataract surgery using the nuclear preslice technique

    Directory of Open Access Journals (Sweden)

    Antonio Eduardo Pereira

    2008-10-01

    Full Text Available OBJETIVOS: Comparar os ciclos de 14% e 67% de ultra-som ligado, módulo contínuo, e controle manual do pulso, no aparelho Sovereign® com sistema WhiteStarTM, para a cirurgia de catarata, utilizando-se a técnica de facoemulsificação "nuclear preslice" nos quesitos: tempo efetivo de ultra-som, porcentual de ultra-som, volume de solução salina e perda de células endoteliais. MÉTODOS: Estudo prospectivo, comparativo de 32 pacientes (38 olhos, com catarata nuclear senil NO3NC3 e NO4NC4 (LOCS III, randomizados em dois grupos, nos quais foi realizada a facoemulsificação com a técnica "nuclear preslice" e controle de pulso manual. No pré-operatório foram realizados: exame oftalmológico completo, biometria, paquimetria central corneana e microscopia especular. No pós-operatório foram avaliados, nas primeiras 24 horas após a cirurgia, a acuidade visual e paquimetria central corneana e, após 3 meses, realizada a microscopia especular. RESULTADOS: As cirurgias com ciclo 67% apresentaram tempo efetivo de ultra-som significantemente maior do que as cirurgias pelo ciclo 14%, em cataratas mais densas. O porcentual de ultra-som no ciclo 67%, em diferentes densidades de cataratas, foi significantemente maior do que no ciclo 14%. Não houve diferenças quanto ao volume de solução salina utilizado nas cirurgias. Não se observou diferença significante na perda de células endoteliais nos diferentes ciclos de ultra-som. Houve correlação positiva significante entre a perda de células endoteliais e as variáveis: tempo efetivo de ultra-som e volume de solução salina utilizado, em ambos os ciclos. CONCLUSÕES: O tempo efetivo e o porcentual de ultra-som foram menores nas cirurgias com ciclo de ultra-som 14%, em cataratas mais densas. O volume de solução salina utilizado e a perda de células endoteliais foram semelhantes em ambos os ciclos. O tempo efetivo de ultra-som e o volume de solução salina foram correlacionados à maior perda de c

  19. Influência do ciclo lunar no parto: mito ou constatação científica? Influencia del ciclo lunar en el parto: mito o constatación científica? Influences of lunar cycle in labor: myth or scientific finding?

    Directory of Open Access Journals (Sweden)

    Aline Bueno

    2010-06-01

    Full Text Available Muitas superstições são encontradas em nossas vidas. Na medicina, uma profissão que se orgulha em métodos baseados em evidências para tratamentos, isso não é uma exceção. Uma superstição que abrange o parto é a influência de determinadas fases do ciclo da lua, mais especificamente a lua cheia. Embora estudos tenham demonstrado que o aumento de partos está relacionado com o ciclo lunar, existe discordância sobre quando ocorre o pico do volume de partos em cada fase da lua. Frente à divergência de resultados existentes na literatura que relaciona os eventos do ciclo lunar com parto, o objetivo desta revisão foi realizar um levantamento bibliográfico na tentativa de esclarecer esta cultura popular com base nos resultados apresentados por diferentes autores.Se encuentran las supersticiones por todas partes en nuestras vidas, y la medicina, una profesión que tiene orgullo acerca de los tratamientos con base en evidencia, no está extinta. La influencia de ciertas fases del ciclo lunar, específicamente la luna llena, es una superstición sobre el parto. Aunque algunos estudios han demostrado un aumento en los partos que se relacionan al ciclo lunar, ha habido discordancia sobre cuando, en el ciclo lunar, el volumen máximo ocurre. Afronte a la divergencia de los resultados existentes en la literatura que relacionan los eventos del ciclo lunar con los partos, el objetivo de esta revisión era explorar la literatura en el esfuerzo de explicar esta cultura popular con la base en los resultados presentado por los diferentes investigadores.Superstitions are found everywhere in our lives, and medicine, a profession that is prides itself on an evidence-based approach to treatment, is not exempt. A superstition that pervades the labor and delivery floor is that it is busier during certain phases of the lunar cycle, specifically the full moon. Although some studies have demonstrated an increase in deliveries that are related to the lunar

  20. CICLO DE VIDA: JUEGO EDUCATIVO MOVIL “EDUCAMOVIL”

    Directory of Open Access Journals (Sweden)

    Judith del Pilar Rodríguez

    2013-12-01

    Full Text Available El presente artículo describe la creación de un modelo de ciclo de vida para el desarrollo de juegos educativos en plataformas móviles, teniendo en cuenta las consideraciones para su construcción como un software de calidad. El modelo para el desarrollo de juegos educativos en plataformas móviles es una guía enmarcada en un entorno pedagógico que facilitará la creación de juegos educativos, abriendo las puertas al desarrollo de videojuegos como prácticas de laboratorio, exploración de ambientes virtuales sin necesidad de materiales costosos y así poder transmitir conocimientos a los estudiantes. La metodología desarrollada se logró a través de la recopilación de información de los distintos modelos de desarrollo de software existentes, en ambientes educativos y su enfoque a plataformas móviles, realizando un estudio de ventajas y desventajas, recomendaciones y algunos recursos de los modelos actuales y su adaptación a estos dispositivos; buscando establecer los pasos básicos, coherentes, involucrados en las fases de análisis, diseño, implementación y pruebas para la creación de juegos, enmarcados en un contexto de estrategias pedagógicas de los modelos existentes y dando la respectiva documentación para el desarrollo en plataformas móviles.

  1. NIH study confirms risk factors for male breast cancer

    Science.gov (United States)

    Pooled data from studies of about 2,400 men with breast cancer and 52,000 men without breast cancer confirmed that risk factors for male breast cancer include obesity, a rare genetic condition called Klinefelter syndrome, and gynecomastia.

  2. Study Ties Alcohol Abuse to Increased Heart Risks

    Science.gov (United States)

    ... medlineplus.gov/news/fullstory_162836.html Study Ties Alcohol Abuse to Increased Heart Risks Association similar to that ... 2009. About 2 percent had been diagnosed with alcohol abuse. The researchers adjusted statistics so they wouldn't ...

  3. Experimental life cycle of Lagochilascaris minor Leiper, 1909 Ciclo evolutivo experimental de Lagochilascaris minor, Leiper 1909

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    Dulcinéa Maria Barbosa Campos

    1992-08-01

    Full Text Available The life cycle of Lagochilascaris minor was studied using material collected from human lesion and applying the experimental model: rodents (mice, hamsters, and carnivorae (cats, dogs. In mice given infective eggs, orally, hatch of the third stage larvae was noted in the gut wall, with migration to liver, lungs, skeletal musculature and subcutaneous tissue becoming, soon after, encysted. In cats infected with skinned carcasses of mice (60 to 235 days of infection it was observed: hatch of third stage larvae from the nodules (cysts in the stomach, migration through the oesophagus, pharynx, trachea, related tissues (rhino-oropharynx, and cervical lymphonodes developing to the mature stage in any of these sites on days 9-20 post inoculation (P.I.. There was no parasite development up to the mature stage in cats inoculated orally with infective eggs, which indicates that the life cycle of this parasite includes an obligatory intermediate host. In one of the cats (fed carcass of infected mice necropsied on day 43 P.I., it was observed the occurence of the self-infective cycle of L. minor in the lung tissues and in the cervical region which was characterized by the finding of eggs in different stages of development, third stage larvae and mature worms. It's believed that some component of the carnivorae gastrointestinal tracts may preclude the development of third stage larvae from L. minor eggs what explains the interruption of the life cycle in animals fed infective eggs. It's also pointed out the role of the intermediate host in the first stages of the life cycle of this helminth.A partir de material colhido de lesões humanas estudou-se o ciclo evolutivo de Lagochilascaris minor empregando-se o modelo experimental: roedores (camundongos, hamster e carnívoros (gatos, cão. Em camundongos inoculados com ovos infectantes, por via oral, observou-se eclosão de larvas de 3º estágio na parede do intestino, migração das mesmas para o fígado, pulm

  4. Análisis cuantitativo de los ciclos económicos

    Directory of Open Access Journals (Sweden)

    Álvarez Vázquez, Nelson J.

    2003-01-01

    Full Text Available El análisis clásico de series temporales asumía que la serie histórica era la suma de tendencia, ciclo regular, estacional y perturbación aleatoria, movimientos que pueden reducirse a tendencia y ciclo. La descomposición en tendencia y ciclo permitía un análisis separado de ambos tipos de movimientos. Esta aproximación suponía que el ciclo era una desviación respecto de la tendencia (determinista a largo plazo, a la cual revertían aquellos ciclos. Cualquier shock aleatorio tenía sólo un efecto transitorio que se agotaba en uno o unos pocos periodos. Este enfoque ha sido hoy abandonado y sustituido por otro de naturaleza probabilística. En particular el artículo de Nelson y Plosser (1982 habría significado el fin de una aproximación ya cuestionada. En este trabajo, los autores contrastaron la hipótesis de raíz unitaria para diversas series macroeconómicas norteamericanas, encontrando que era imposible rechazarla. Mientras que en la primitiva visión, las fluctuaciones se contemplaban como desviaciones respecto a la tendencia determinista, la existencia de raíz unitaria significa que todas las fluctuaciones representan cambios 2 permanentes en la tendencia a largo plazo, dado que el efecto de cualquier shock, permanece indefinidamente, en lugar de agotarse con el paso del tiempo. De ahí la importancia de la existencia de raíz unitaria en el análisis cuantitativo del ciclo. Sólo mediante la diferenciación se alcanzaría la estacionariedad. En caso contrario, es decir si se elimina una tendencia temporal a una serie generada por un proceso de camino aleatorio (el ejemplo paradigmático de tendencia estocástica, se obtendrán inferencias espurias sobre el ciclo (Nelson y Kang, 1981. En esta cuestión como en tantas otras, es perceptible la evolución metodológica experimentada por la econometría, que se ha desplazado desde un enfoque determinista, donde lo que importaban eran cuestiones como la obtención de la cronolog

  5. L’ipotesi del ciclo vitale, la politica fiscale e la previdenza sociale (The hypothesis of the life cycle, fiscal policy and social security

    Directory of Open Access Journals (Sweden)

    Tullio Jappelli

    2012-04-01

    Full Text Available Il lavoro riassume le principali implicazioni dell’ipotesi del ciclo vitale per quanto riguarda il risparmio individuale e aggregato, la politica fiscale e la previdenza sociale, soffermandosi sui contributi più importanti di Modigliani su questi temi. Anche se non è facile conciliare alcuni risultati empirici recenti con l’ipotesi del ciclo vitale, soprattutto gli aspetti di inerzia, miopia e comportamento irrazionale documentati nella letteratura comportamentale, gli studi di Modigliani rappresentano ancora oggi la base di riferimento principale per studiare le decisioni di risparmio individuali e per operare scelte di politica economica.    The paper summarizes the main implications of the life cycle hypothesis regarding the individual and aggregate saving, fiscal policy and social security, focusing on the most important contributions of Modigliani on these issues. Although it is not easy to reconcile some recent empirical results with the hypothesis of the life cycle, especially the aspects of inertia, myopia and irrational behavior documented in the literature behavioral, the studies of Modigliani still represent the basis of reference for the study of individual savings decisions and to make policy choices.  JEL Codes: D91Keywords: ciclo vitale, risparmio, modigliani, politica economica

  6. Vestibular characterization in the menstrual cycle Caracterização vestibular no ciclo menstrual

    Directory of Open Access Journals (Sweden)

    Cintia Ishii

    2009-06-01

    Full Text Available Hormonal disorders in the menstrual cycle can affect labyrinthine fluid homeostasis, causing balance and hearing dysfunctions. STUDY DESIGN: Clinical prospective. AIM: compare the results from vestibular tests in young women, in the premenstrual and postmenstrual periods. MATERIALS AND METHODS: twenty women were selected with ages ranging from 18 to 35 years, who were not using any kind of contraceptive method for at least six months, and without vestibular or hearing complaints. The test was carried out in each subject before and after the menstrual period, respecting the limit of ten days before or after menstruation. RESULTS: there was a statistically significant difference in the menstrual cycle phases only in the following vestibular tests: calibration, saccadic movements, PRPD and caloric-induced nystagmus. We also noticed that age; a regular menstrual cycle; hearing loss or dizziness cases in the family; and premenstrual symptoms such as tinnitus, headache, sleep disorders, anxiety, nausea and hyperacusis can interfere in the vestibular test. CONCLUSION: there are differences in the vestibular tests of healthy women when comparing their pre and postmenstrual periods.As alterações hormonais do ciclo menstrual podem comprometer a homeostase dos fluidos labirínticos, gerando alterações no equilíbrio e na audição. FORMA DO ESTUDO: Clínico prospectivo. OBJETIVO: Comparar os resultados dos testes do exame vestibular em mulheres jovens, nos períodos pré e pós-menstrual. MATERIAL E MÉTODO: Foram selecionadas vinte mulheres, entre dezoito e trinta e cinco anos, que não fizessem uso de qualquer tipo de anticoncepcional, com audição normal e sem queixas vestibulares. O exame vestibular foi realizado em cada participante no período pré e no período pós-menstrual, em ordem aleatória, e respeitando o limite de até dez dias antes do início da menstruação e até dez dias após o início da menstruação. RESULTADO: Foi observada

  7. Organização da escolaridade em ciclos: representações sociais de professores

    Directory of Open Access Journals (Sweden)

    Luciene Alves Miguez Naiff

    2013-01-01

    Full Text Available O sistema de ciclos de aprendizagem recebe no Brasil uma miríade de denominações, dentre elas: ciclos de formação, regime de progressão continuada, bloco inicial de alfabetização e ciclos do ensino fundamental (Mainardes, 2009. Ele vem sendo defendido como uma proposta inclusiva que leva em conta as variações no curso de aprendizagem dos alunos e evita a evasão ocasionada pelas multirrepetências. O aporte teórico escolhido, a Teoria das Representações Sociais, se mostra adequado e pertinente ao presente estudo, já que privilegia a comunicação entre os grupos sociais com o objetivo de uma maior adaptação à realidade que se impõe. O presente artigo teve como objetivo identificar e comparar as representações de 168 professores da rede municipal de ensino de Niterói e do Rio de Janeiro acerca dos "ciclos de aprendizagem". A análise dos dados aponta para representações negativas atreladas a posicionamentos contrários à organização em ciclos em ambos os grupos.

  8. La teoria del ciclo vitale del risparmio di Modigliani cinquant’anni dopo

    Directory of Open Access Journals (Sweden)

    Mauro Baranzini

    2005-06-01

    Full Text Available Nei primi anni ’50 Franco Modigliani, insieme a Richard Brumberg e ad Albert Ando, formulò lateoria del ciclo vitale del consumo e del risparmio, che ha riscosso un enorme e indiscussosuccesso per almeno tre decenni. Tuttavia, a partire dai primi anni ’80 la teoria del ciclo vitale èstata criticata in modo sempre più serrato, per almeno quattro ragioni. La prima consistenell’esistenza di una significativa trasmissione intergenerazionale della ricchezza, da ricondurre acause esogene al modello del ciclo vitale. La seconda ragione è rappresentata dalla crescenteevidenza che i ricchi continuano a risparmiare in misura maggiore rispetto ai meno fortunati,come, in effetti, Keynes sosteneva. Il terzo motivo è che vi sono prove sempre più evidenti,almeno nell’Europa occidentale e in Giappone, che le famiglie giovani, durante i venti e i trentaanni di età, risparmiano una quota positiva e crescente del proprio reddito, e ciò si pone indeciso contrasto con la versione originaria della teoria del ciclo vitale. Infine, numerosi lavoriempirici hanno rilevato che i pensionati accantonano una parte elevata del proprio reddito. Ciòimpone un serio ripensamento dell’approccio della teoria del ciclo vitale, che interessa sia l’analisieconomica sia la politica economica.

  9. Study of a risk-based piping inspection guideline system.

    Science.gov (United States)

    Tien, Shiaw-Wen; Hwang, Wen-Tsung; Tsai, Chih-Hung

    2007-02-01

    A risk-based inspection system and a piping inspection guideline model were developed in this study. The research procedure consists of two parts--the building of a risk-based inspection model for piping and the construction of a risk-based piping inspection guideline model. Field visits at the plant were conducted to develop the risk-based inspection and strategic analysis system. A knowledge-based model had been built in accordance with international standards and local government regulations, and the rational unified process was applied for reducing the discrepancy in the development of the models. The models had been designed to analyze damage factors, damage models, and potential damage positions of piping in the petrochemical plants. The purpose of this study was to provide inspection-related personnel with the optimal planning tools for piping inspections, hence, to enable effective predictions of potential piping risks and to enhance the better degree of safety in plant operations that the petrochemical industries can be expected to achieve. A risk analysis was conducted on the piping system of a petrochemical plant. The outcome indicated that most of the risks resulted from a small number of pipelines.

  10. Computational program to design heat pumps by compression (ciclo 1.0); Programa computacional para diseno de bombas de calor por compresion (ciclo 1.0)

    Energy Technology Data Exchange (ETDEWEB)

    De Alba Rosano, Mauricio [CIE, UNAM, Temixco, Morelos (Mexico)

    2000-07-01

    A new computational program has been developed in order to design single stage compression heat pumps. This software, named CICLO 1.0 allows the design of water-water, water-air, air-water and air-air heat pumps, for industrial and residential applications. CICLO 1.0 simulates three types of compressors: reciprocating, screw and scroll. Also has a data base created with REFPROP software which includes eleven refrigerants. The condenser and evaporator simulation includes global conductance (UA) determination, and when one or both are shell and tube's type, this software shows the even number of tube passes by shell. The software determines the best compressor and refrigerant setup taking the COP as a parameter; in order to obtain this, is necessary to know the inlet/outlet conditions of the fluid to be heated, the inlet conditions of the fluid that gives heat, and the electric motor efficiency that drives the compressor. The afforded results by CICLO 1.0 are: operation conditions from compression cycle, that means, pressures and temperatures at the inlet/outlet from every heat pump component are determined: as well as refrigerant mass flux, COP, power required by compressor, volumetric and isentropic efficiencies, heat exchangers global conductance and more data. CICLO 1.0 has been executed with heat pump data that nowadays are operating, and the results from the simulation have been very similar each other with data reported from operational facilities. [Spanish] Se ha desarrollado un nuevo programa computacional para el diseno de bombas de calor por compresion de vapor de una sola etapa. Este programa, CICLO 1.0, permite el diseno de bombas de calor de tipo: agua-agua, agua-aire, aire-agua y aire-aire, que se utilicen para aplicaciones industriales, de servicios y residenciales. CICLO 1.0 simula tres tipos de compresores: reciprocante, de tornillo y scroll: cuenta con una base de datos de refrigerantes creada con el programa REFPROP la cual incluye once

  11. Analysis of the alcohol consumption phenomenon among adolescents: study carried out with adolescents in intermediate public education Análisis del fenómeno del consumo de alcohol entre adolescentes: estudio realizado con adolescentes del 3º ciclo de escuelas públicas Análise do fenômeno do consumo de álcool em adolescentes: estudo realizado com adolescentes do 3º ciclo de escolas públicas

    Directory of Open Access Journals (Sweden)

    Teresa Barroso

    2009-06-01

    Full Text Available This study aimed to evaluate the alcohol consumption phenomenon in public schools in Coimbra, Portugal (7th, 8th and 9th grades for the implementation of a preventive program of alcohol use/abuse. This is a quantitative, descriptive and correlational study. The sample included 654 students (51.5% female between 12 and 18 years of age. The Alcohol Expectancy Questionnaire - Adolescent form (AEQ-A and the Questionnaire of Knowledge on Alcohol were used for data collection. Results show that positive expectancy on alcohol is discriminative of consumption and occurrence of intoxication. Positive expectancy exists even before adolescents have significant experiences with alcohol consumption and increases with age, which reinforces the need for early preventive effort. These results permitted to improve the prevention program included in the school curriculum of the 7th grade students.Este estudio tiene como objetivo evaluar el fenómeno del consumo de alcohol en las escuelas públicas de la ciudad de Coimbra (7º,8º y 9º para implementar, en la práctica, un programa de prevención del uso/abuso del consumo alcohólico excesivo. Es un estudio del tipo cuantitativo, descriptivo y de correlación. La muestra incluyó 654 estudiantes (51.5% del sexo femenino, con edades entre 12 y 18 años. El Cuestionario de Expectativas referentes al Alcohol de estudiantes - Formato Adolescentes (CEA-A y el cuestionario del conocimiento referente al alcohol fueron utilizados para obtener los datos. Los resultados demostraron que las expectativas positivas referentes al alcohol hacen una diferencia entre el consumo de alcohol y la ocurrencia de la embriaguez; inclusive, esta discriminación existe entre los adolescentes antes de tener experiencias significativas con el consumo de alcohol y aumentan con la edad. Reforzando la necesidad de desarrollar precozmente esfuerzos preventivos. Estos resultados permitieron el perfeccionamiento del programa de prevención que

  12. Flood risk management: cases studies in French Mediterranean area

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    Defossez Stéphanie

    2016-01-01

    Full Text Available In France, for a long time, flood risk management has only oriented to controlling flood hazard with structural measures such as dikes. But since 1990’s many events have proved they have not totally efficient measures. So, institutions decided it’s necessary to manage flood risk with others ways like prevention. Risk management is so organize about holistic policies with different stakeholders and societies exposed at risk. Our study have the aim to demonstrate through several examples how flood risk is manage in French Mediterranean area. Post event feedback permit us to evaluate damage and crisis management. This method is use for show if this strategies is efficient or not. This study demonstrate how is risk management in France. Regulations are they efficient, so have they an influence about the reduction of deaths and damages? Individual measures are they more important than collective action? Finally, what policies and strategies are used and effective? The main results about cases studies show that natural event has most important that publics policies and it determines preventive policies.

  13. Analysis of hyaluronic acid concentration in rat vocal folds during estral and gravidic puerperal cycles Análise da concentração do ácido hialurônico nas pregas vocais de ratas durante o ciclo estral e ciclo gravídico-puerperal

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    José Eduardo de Sá Pedroso

    2009-10-01

    Full Text Available Hormone plays an important role in the larynx. Among other substances, vocal folds contain hyaluronic acid, which tissue concentration may vary according to hormone action. AIM: the objective of this study is to analyze hyaluronic acid concentration in the vocal folds during estral and gravidic-puerperal cycles. MATERIALS AND METHODS: Experimental study. 40 adult rats were divided into two groups. In the first group we used 20 rats to establish the concentration of hyaluronic acid during the estral cycle and in the second group, 20 animals were submitted to the same procedure but during the gravidic-puerperal cycle. RESULTS: Variations in hyaluronic acid concentration was not observed during the estral cycle. In the gravidic puerperal cycle group, an increase in hyaluronic acid concentration was observed in the puerperal subgroup. Comparing the two groups of estral and gravidic-puerperal cycles, no difference was observed. CONCLUSIONS: In comparing all subgroups of estral and gravidic-puerperal cycles, an increase in hyaluronic acid concentration was noticed only in the puerperal phase.Os hormônios exercem importante influência sobre a laringe. A prega vocal contém, entre outras substâncias, o ácido hialurônico, cuja concentração nos tecidos pode variar com a ação dos hormônios. OBJETIVO: O objetivo deste trabalho é analisar comparativamente a concentração do ácido hialurônico nas pregas vocais de ratas durante o ciclo estral e ciclo gravídico-puerperal. FORMA DE ESTUDO: Experimental. MATERIAL E MÉTODO: Foram utilizadas 40 ratas adultas, divididas em dois grupos, no primeiro grupo utilizamos 20 ratas para determinação da concentração do ácido hialurônico no ciclo estral, no segundo grupo, também de 20 animais, foi realizado o mesmo experimento no ciclo gravídico-puerperal. RESULTADOS: No grupo do ciclo estral não observou-se variação da concentração do ácido hialurônico. No grupo do ciclo grav

  14. Study on territorial risk assessment in Beibu Gulf of Guangxi

    Science.gov (United States)

    Wang, Y.; Hou, L. S.; Zhang, M. S.

    2016-08-01

    This study is based on the theories of terrestrial exploration risk in the Beibu Gulf Economic Zone in the Guangxi Zhuang Autonomous Region. Using ArcGIS and modelling methods, the spatial distributions of resources and environmental carrying capacity, terrestrial exploration dynamics, and terrestrial exploration potential are studied and evaluated in an integrated way. The results of the study are as follows: Mashan county, Longan county, Luchuan county, et al. have some low-risk land that can be explored, and infrastructure investment should be increased in these locations. Whereas, low-risk terrestrial development is possible in Qinzhou city, Heng county, Longan county, et al. and should be carried out in a planned and gradual fashion. The medium risk regions are distributed all over the region, but are concentrated in the city area of Nanning. However, the middle and north parts of Yulin city, the south part of Chongzuo city, Qinnan district, et al. are also in the same category and priority can be given to improve the quality and efficiency of these regions. The high risk regions, mainly distribute in the Liangqin district, Yining district, Binyang county, et al. This region should focus on the development principles of priority protection, appropriate development, and point-like development. Whereas, the extremely-high-risk areas, of which more than 60% are in Tiandeng county, Daxin county, Shanglin county, et al., are unsuitable for further development. The three-dimensional risk matrix method can make up for the deficiencies of other methods and has broad prospects in regional terrestrial development risk assessment.

  15. Ciclos de desenvolvimento humano e formação de educadores

    Directory of Open Access Journals (Sweden)

    Arroyo Miguel G.

    1999-01-01

    Full Text Available Os ciclos não são mais uma proposta isolada de algumas escolas, a nova LDB os legitimou e estão sendo adotados por muitas redes escolares. Este texto se pergunta pelo tipo de profissional que está sendo formado nessa modalidade de organização do trabalho pedagógico. A reflexão está estruturada em duas partes. A primeira reflete sobre o caráter formador do repensar das concepções e práticas de formação que acontecem na implantação dos ciclos. A segunda parte reflete sobre as virtualidades formadoras de todo o processo de desconstrução de uma estrutura centrada nas Temporalidades ou Ciclos do Desenvolvimento Humano.

  16. Integrated Risk Research. Case of Study: Motozintla, Chiapas, Mexico

    Science.gov (United States)

    Novelo-Casanova, D. A.; Jaimes, M.

    2015-12-01

    This integrated risk research include the analysis of all components of individual constituents of risk such hazard identification, hazard exposure, and vulnerability. We determined risk to natural hazards in the community of Motozintla located in southern Mexico in the state of Chiapas (15.37ºN, 92.25ºW. Due to its geographical and geological location, this community is continuously exposed mainly to earthquakes, landslides and floods. We developed integrated studies and analysis of seismic zonation, landslides and flood susceptibility using standard methodologies. Vulnerability was quantified from data collected from local families interviews considering five social variables: characteristics of housing construction, availability of basic public services, family economic conditions, existing community plans for disaster preparedness, and risk perception. Local families surveyed were randomly selected considering a sample statistically significant. Our results were spatially represented using a Geographical Information System (GIS). Structural vulnerability curves were generated for typical housing constructions. Our integrated risk analysis demonstrates that the community of Motozintla has a high level of structural and socio-economical risk to floods and earthquakes. More than half of the population does not know any existing Civil Protection Plan and perceive that they are in high risk to landslides and floods. Although the community is located in a high seismic risk zone, most of the local people believe that cannot be impacted by a large earthquake. These natural and social conditions indicate that the community of Motozintla has a very high level of risk to natural hazards. This research will support local decision makers in developing an integrated comprehensive natural hazards mitigation and prevention program.

  17. A social work study high-risk behavior among teenagers

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Iravani

    2012-01-01

    Full Text Available Teenagers are believed the people who are supposed to build the world's future. High-risk behaviors such as addiction to drugs, smoking cigarettes, sex, etc. could significantly hurts teenagers and there must be some supporting programs to reduce these issues as much as possible. This paper performs an empirical investigation to study the different factors influencing high- risk behavior among teenagers who live in a city of Esfahan, Iran. The proposed study designs a questionnaire and distribute between two groups of female and male teenagers. The results indicate that while there is a meaningful relationship between high-risk behaviors and average high school marks among male students there is no meaningful relationship between high-risk behaviors and high school grades among female students. The results also indicate that there is a meaningful difference between gender and high-risk behavior. The season of birth for female and male students is another important factor for having high-risk behaviors. While the order of birth plays an important role among male students, the order of birth is not an important factor among female teenagers. Finally, the results indicate that teenagers' parental financial affordability plays a vital role on both female and male teenagers.

  18. Una nueva copla sefardí antigua del ciclo de la reina Ester (Purim

    Directory of Open Access Journals (Sweden)

    Hassán, Iacob M.

    2007-12-01

    Full Text Available In this posthumous article (edited by Elena Romero, the author tries to determine the classical corpus of the Purim “Coplas” of the Queen Esther cycle, referring to their strophic structure, their authors and the problems of edition and diffusion. Likewise, this study represents a significant step in the establishment of a corpus of Purim “Coplas” known as “novísimas.” An edition is presented here of an hitherto unknown “Copla” belonging to the first group: La bebienda de Purim.

    En el presente artículo (postumo y editado por Elena Romero se determina el corpus clásico de las coplas de Purim del «ciclo de la reina Ester», aludiendo a su estrofismo, autores y problemt mática de las ediciones y su difusión; asimismo se avanza en la determinación del corpus de las coplas de Purim llamadas «novísimas». Finalmente se lleva a cabo la edición de una copla del primer grupo hasta ahora desconocida: La bebienda de Purim.

  19. Arquitetura do sono diurno e ciclo vigília-sono em enfermeiros nos turnos de trabalho La arquitectura del sueño diurno y del ciclo de vigilia en los enfermeros durante los turno de trabajo The architecture of day sleeping and the sleep-wake cycle in nurses in their working shifts

    Directory of Open Access Journals (Sweden)

    Milva Maria Figueiredo De Martino

    2009-03-01

    Full Text Available Este estudo teve como objetivos verificar a arquitetura do sono diurno após o trabalho noturno, e as características do ciclo vigília-sono em enfermeiras de diferentes turnos. Foi realizado no Hospital de Clínicas da Faculdade de Medicina de Ribeirão Preto, USP. Através do diário de sono avaliou-se o ciclo vigília-sono em (n=36 sujeitos, com média de idade de 30. Destes apenas cinco fizeram medidas da polissono-grafia no Laboratório de Sono. Apresentaram qualidade de sono noturno melhor, os registros polissonográficos identificaram sono diurno com períodos curtos e incompletos quanto aos ciclos, muitos despertares que caracterizaram pouca eficácia de sono.Este estudio tuvo como objetivos verificar la arquitectura del sueño diurno después del trabajo nocturno, y las características del ciclo de vigilia-sueño en enfermeras de diferentes turnos. El estudio fue realizado en el Hospital de Clínicas de la Facultad de Medicina en la ciudad de Ribeirao Preto, USP. A través del diario de sueño se evaluó el ciclo de vigilia-sueño en 36 sujetos, que tuvieron un promedio de edad de 30 años. Entre estos, apenas cinco realizaron medidas de la polisonografía en el Laboratorio de Sueño; los que presentaron una mejoría en la calidad de sueño nocturno; los registros polisonográficos en lo que se refiere a los ciclos, identificaron un sueño diurno con períodos cortos e incompletos; también se constató muchos despertares lo que caracteriza la poca eficacia de sueño.This study aimed to observe the architecture of day sleeping after a night of work, and the characteristics of the sleep-wake cycle in nurses working in different shifts. The study was performed at the Hospital de Clínicas da Faculdade de Medicina de Ribeirão Preto, USP. The sleep-wake cycle was evaluated through the sleep diary in (n=36 subjects, with an average age of 30 years. Of these, only five performed polysomnography measurements at the Sleep Laboratory

  20. Propuesta de Ciclo de vida de los proyectos de Desarrollo Empresarial

    OpenAIRE

    Antonio M. Navarro López

    2009-01-01

    Todo proyecto se divide en distintas fases, habitualmente secuenciales, que permiten un control sobre la evolución del proyecto y habilitan su gestión. El conjunto de fases de un proyecto se denomina "ciclo de vida"; de un proyecto, se expone una serie de puntos de vista de diferentes autores sobre el ciclo de vida de los proyectos, incluyendo la caracterización que el autor propone para los proyectos de Desarrollo Empresarial que aplican el Perfeccionamiento Empresarial y que gestionan la In...

  1. Efecto del ciclo de efectivo sobre la rentabilidad de las firmas colombianas

    OpenAIRE

    Arcos Mora, Mauricio Alejandro; Benavides Franco, Julián

    2008-01-01

    Este artículo analiza el impacto del ciclo de efectivo sobre la rentabilidad de las empresas no financieras en Colombia. Se ha identificado de manera empírica el ciclo de efectivo como una medida apropiada para evaluar la gestión financiera y en especial como un elemento determinante de la administración de capital de trabajo. De igual forma, la literatura financiera ha sido recurrente en mostrar la relación que existe entre una administración de capital de trabajo adecuada y las mejoras en l...

  2. A organização do ensino fundamental em ciclos: algumas questões

    OpenAIRE

    Ocimar Munhoz Alavarse

    2009-01-01

    En el artículo son problematizados algunos de los aspectos relacionados a la organización de la educación básica en ciclos, partiéndose de iniciativas en materia de educación de redes públicas y de la literatura sobre el tema. La implantación de los ciclos, con diferencias de diversos órdenes, se ha intensificado con la Ley de Directrices y Bases de 1996 y se presenta como una alternativa a la organización de la enseñanza por grados y al fracaso escolar, especialmente por cuenta de las altas ...

  3. O ciclo de vida da carreira profissional docente do ensino religioso

    OpenAIRE

    Araújo, Narjara Lins de

    2014-01-01

    De acordo com a teoria do Ciclo de vida da Carreira Profissional Docente na perspectiva de Huberman (1992) existem cinco possíveis fases que os professores podem vivenciar ao longo da profissão docente. Com isso, tem- se como objetivo geral desse estudo consiste em compreender o Ciclo de Vida da Carreira Profissional de Professores do Ensino Religioso de acordo com Huberman (1992). E como objetivo específico, verificar entre os professores de ensino religioso os conflitos e dilemas presentes ...

  4. Ciclo de desarrollo de Trigona (Tetragonisca angustula, Latreille 1811 (Hymenoptera, Trigonini

    Directory of Open Access Journals (Sweden)

    Villa Lopera Antonio

    1989-06-01

    Full Text Available

    Se estudió el ciclo de desarrollo de una abeja sin aguijón: Trigona (Tetragonisca angustula. Latreille 1811 (Hymenoptera. Trigonini. Los resultados fueron los siguientes: El periodo comprendido entre la postura del huevo y la emergencia del imago, es, en las obreras, de 36.5 días en promedio. La duración del ciclo se hace mayor a medida que las celdas se alejan del centro del panal. Se determinaron 3 instares larvales y 5 fases pupales para obreras.

  5. Análisis del ciclo de vida de la ventana de madera.

    OpenAIRE

    2011-01-01

    Analizar en todos los procesos que forman el ciclo de vida de la ventana de madera “modelo”, todas las entradas y salidas tanto de materiales como de energía, desde el proceso de extracción de materia prima, hasta su llegada a vertedero o reciclaje para formar parte de un nuevo producto, con el fin de obtener las emisiones de CO2 que se generan en todo el ciclo. Y a su vez, analizar el efecto ambiental del producto en cada uno de sus procesos de fabricación y a lo largo de toda su vida, a tra...

  6. Diagnóstico da fase do ciclo de vida organizacional

    OpenAIRE

    Lezana, Álvaro Guillermo Rojas; Grapeggia, Mariana

    2006-01-01

    O presente artigo tem como objetivo desenvolver e testar um instrumento de coleta de dados que permita ao empreendedor identificar a fase do ciclo de vida que a sua empresa atravessa, para poder planejar o futuro e superar as etapas passadas e presente.  Para tal, se faz uma revisão dos modelos de ciclo de vida das organizações (CVO) e, dentre estes, se escolhe o desenvolvido por Larry Greiner por apresentar dois parâmetros de avaliação: o estilo gerencial e o tipo de crise que a organização ...

  7. [Oral contraceptive pill and thrombotic risk: epidemiological studies].

    Science.gov (United States)

    Fruzzetti, F; Perini, D; Spirito, N; Manca, R

    2012-12-01

    The venous thromboembolism (VTE) is a rare event during childbearing age and during the assumption of combined oral contraceptive. The absolute risk of VTE in users of combined oral contraceptives is 20-30 per 100000 women years. A number of case-control studies published in recent years have shown an apparent increase in the risk of VTE among users of oral contraceptives (OCs) containing desogestrel, gestodene, drospirenone and cyproterone, relative to the use of levonorgestrel. The data derived from these recent studies is of borderline statistical significance because any important factors are not considered to evaluate the real correlation between the assumption of OCs and risk of venous thromboembolism. Among the factors that should be considered, there are: EE dose, duration of use, coexistance of other risk factors of venous thromboembolism (age, BMI, familiarity, surgical interventions) and other prescription bias. The lack of these factors is likely to contribute to the increased risk of venous thromboembolism observed in users of third-generation OCs when compared to that in users of second-generation OCs. To date, because of the inadequacy of epidemiological studies, the data about the correlation between OCs and TVE, are not conclusive and it will be necessary to carry out other studies to clarify this debating point, definitively.

  8. Risk factors for oligodendroglial tumors: a pooled international study

    DEFF Research Database (Denmark)

    McCarthy, Bridget J; Rankin, Kristin M; Aldape, Ken

    2011-01-01

    (CIs), adjusted for age group, gender, and study site. Data on 617 cases and 1260 controls were available for analyses. Using data from all 7 studies, history of allergies and/or asthma was associated with a decreased risk of anaplastic oligodendroglioma (OR = 0.6; 95% CI: 0.4-0.9), and history...

  9. Diabetes mellitus and the risk of dementia - The Rotterdam Study

    NARCIS (Netherlands)

    Ott, A; Stolk, RP; van Harskamp, F; Pols, HAP; Hofman, A; Breteler, MMB

    1999-01-01

    Objective: To determine the influence of type 2 diabetes mellitus on the risk of dementia and AD. Background: Both dementia and diabetes are frequent disorders in elderly people. Methods: Prospective population-based cohort study among 6,370 elderly subjects. At baseline study participants were exam

  10. Computational Study of Scenarios Regarding Explosion Risk Mitigation

    Science.gov (United States)

    Vlasin, Nicolae-Ioan; Mihai Pasculescu, Vlad; Florea, Gheorghe-Daniel; Cornel Suvar, Marius

    2016-10-01

    Exploration in order to discover new deposits of natural gas, upgrading techniques to exploit these resources and new ways to convert the heat capacity of these gases into industrial usable energy is the research areas of great interest around the globe. But all activities involving the handling of natural gas (exploitation, transport, combustion) are subjected to the same type of risk: the risk to explosion. Experiments carried out physical scenarios to determine ways to reduce this risk can be extremely costly, requiring suitable premises, equipment and apparatus, manpower, time and, not least, presenting the risk of personnel injury. Taking in account the above mentioned, the present paper deals with the possibility of studying the scenarios of gas explosion type events in virtual domain, exemplifying by performing a computer simulation of a stoichiometric air - methane explosion (methane is the main component of natural gas). The advantages of computer-assisted imply are the possibility of using complex virtual geometries of any form as the area of deployment phenomenon, the use of the same geometry for an infinite number of settings of initial parameters as input, total elimination the risk of personnel injury, decrease the execution time etc. Although computer simulations are hardware resources consuming and require specialized personnel to use the CFD (Computational Fluid Dynamics) techniques, the costs and risks associated with these methods are greatly diminished, presenting, in the same time, a major benefit in terms of execution time.

  11. Offshore risk assessment principles, modelling and applications of QRA studies

    CERN Document Server

    Vinnem, Jan-Erik

    2007-01-01

    attempt has been made to capture the new trends in the regulations, to the extent they are known. There have over the last 10-15 years been published a few textbooks on risk assessment, most of them are devoted to relatively generic topics. Some are also focused on the risk management aspects, in general and with offshore applicability. None are known to address the needs and topics of the use of QRA studies by the offshore industry in particular. The present work is trying to bridge this gap. The use of QRA studies is somewhat special in Northern Europe, and par- cularly in Norway. The use of

  12. Multiple Sclerosis Associated Risk Factors: A Case-Control Study

    Directory of Open Access Journals (Sweden)

    Jalal POOROLAJAL

    2015-11-01

    Full Text Available Background: Hamadan Province is one of the high-risk regions in Iran for Multiple sclerosis (MS. A majority of the epidemiological studies conducted in Iran addressing MS are descriptive. This study was conducted to assess MS and its associated risk factors in Hamadan Province, the west of Iran.Methods: This case-control study compared 100 patients with MS (case group and 100 patients with acute infectious diseases (control group from September 2013 to March 2014. A checklist was used to assess the demographic, medical, and family history of the patients. The Friedman-Rosenman questionnaire was also used to assess personality type. Statistical analysis was performed using logistic regression model with Stata 11 software program.Results: The adjusted odds ratio (OR estimate of MS was 4.37 (95% CI: 2.33, 8.20 for females compared to males; 0.15 (95% CI: 0.06, 0.43 for people aged above 50 years compared to aged 14 to 29 years; 0.44 (95% CI: 0.21, 0.91 for overweight or obese people compared to normal weights. Crude OR indicated a significant association between the occurrence of MS and exclusive breast feeding, season of birth, and smoking. However, the association was not statistically significant after adjustment for other covariates.Conclusion: The risk of MS is significantly lower in male gender, obese/overweight, and old people. Furthermore, non-smoking, non-exclusive breast-feeding, and born in autumn may increase the risk of MS but need further investigation. However, long-term large prospective cohort studies are needed to investigate the true effect of the potential risk factors on MS. Keywords: Multiple sclerosis, Risk factors, Case-control study, Iran

  13. Gasification integrated to combined cycles; Gasificacion integrada a ciclos combinados

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez M, Manuel F; Alcaraz C, Agustin M [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2001-07-01

    de metales. Finalmente, en los nuevos esquemas de refinacion del petroleo se preve utilizar la coquizacion para aprovechar mejor el ondo de barril. El residuo producto de este proceso, conocido como coque de refineria, tiene un bajo valor comercial, un poder calorifico elevado y un alto contenido de azufre y metales. La gasificacion ha sido desarrollada en las ultimas dos decadas, en los paises altamente industrializados, como una alternativa para la generacion eficiente y limpia de electricidad a partir de combustibles sucios, asi como para la obtencion de ciertos combustibles en lugares donde no se tiene acceso al petroleo, pero si al carbon. Esta tecnologia cumple los reglamentos mas estrictos del mundo en lo que a emisiones contaminantes se refiere y es la unica solucion, junto a los lechos fluidizados, para los problemas que presentan algunos combustibles que son dificiles de quemar con tecnologias convencionales, como el carbon mineral, el coque de petroleo e incluso los residuos liquidos de la refinacion. Con base en los anterior, es posible pensar en la integracion de esta tecnologia a una planta de ciclo combinado para la generacion de electricidad o a una refineria generando vapor, energia electrica, hidrogeno y otros insumos a un costo competitivo, de manera tal que se resuelven los problemas de manejo y almacenamiento de los residuos; por otro lado se maximiza el aprovechamiento de los recursos energeticos primarios en el pais.

  14. Trauma & the reproductive lifecycle in women Trauma e o ciclo reprodutivo feminino

    Directory of Open Access Journals (Sweden)

    Leslie Born

    2005-10-01

    Full Text Available Women are at significantly higher risk for developing post-traumatic stress disorder (PTSD than men, resulting in increased psychosocial burden and healthcare related costs. Recent research has shown complex interactions between the impact of traumatic experiences, and the reproductive lifecycle in women. For example, women suffering from premenstrual dysphoric disorder (PMDD who also report a history of sexual or physical abuse are more likely to present with different neuroendocrine reactivity to stressors, when compared to premenstrual dysphoric disorder subjects without prior history of trauma or abuse or non-premenstrual dysphoric disorder subjects. In addition, women with a history of abuse or trauma may experience re-emergence of symptoms during pregnancy. Lastly, females who experience miscarriage may present with even higher prevalence rates of post-traumatic stress disorder symptoms. In this manuscript we examine the existing data on gender differences in post-traumatic stress disorder, with particular focus on psychological and physiological factors that might be relevant to the development of symptoms after exposure to traumatic events associated with the reproductive life cycle. Current options available for the treatment of such symptoms, including group and counselling therapies and debriefing are critically reviewed.Mulheres estão sujeitas a um maior risco para o desenvolvimento de transtorno de estresse pós-traumático (TEPT do que os homens, o que acarreta prejuízos e custos significativos do ponto de vista psicossocial e de saúde pública. Estudos recentes mostram interações complexas entre o impacto de experiências traumáticas e o ciclo reprodutivo feminino. Por exemplo, mulheres com transtorno disfórico pré-menstrual (TDPM, que também relatam histórico de trauma ou abuso físico, estão mais sujeitas a apresentar uma resposta neuroendócrina diferenciada após exposição a um fator ou evento estressante, quando

  15. Environmental risk assessment of ivermectin: A case study.

    Science.gov (United States)

    Liebig, Markus; Fernandez, Alvaro Alonso; Blübaum-Gronau, Elke; Boxall, Alistair; Brinke, Marvin; Carbonell, Gregoria; Egeler, Philipp; Fenner, Kathrin; Fernandez, Carlos; Fink, Guido; Garric, Jeanne; Halling-Sørensen, Bent; Knacker, Thomas; Krogh, Kristine A; Küster, Anette; Löffler, Dirk; Cots, Miguel Angel Porcel; Pope, Louise; Prasse, Carsten; Römbke, Jörg; Rönnefahrt, Ines; Schneider, Manuel K; Schweitzer, Natascha; Tarazona, José V; Ternes, Thomas A; Traunspurger, Walter; Wehrhan, Anne; Duis, Karen

    2010-07-01

    The veterinary parasiticide ivermectin was selected as a case study compound within the project ERAPharm (Environmental Risk Assessment of Pharmaceuticals). Based on experimental data generated within ERAPharm and additional literature data, an environmental risk assessment (ERA) was performed mainly according to international and European guidelines. For the environmental compartments surface water, sediment, and dung, a risk was indicated at all levels of the tiered assessment approach. Only for soil was no risk indicated after the lower tier assessment. However, the use of effects data from additional 2-species and multispecies studies resulted in a risk indication for collembolans. Although previously performed ERAs for ivermectin revealed no concern for the aquatic compartment, and transient effects on dung-insect populations were not considered as relevant, the present ERA clearly demonstrates unacceptable risks for all investigated environmental compartments and hence suggests the necessity of reassessing ivermectin-containing products. Based on this case study, several gaps in the existing guidelines for ERA of pharmaceuticals were shown and improvements have been suggested. The action limit at the start of the ERA, for example, is not protective for substances such as ivermectin when used on intensively reared animals. Furthermore, initial predicted environmental concentrations (PECs) of ivermectin in soil were estimated to be lower than refined PECs, indicating that the currently used tiered approach for exposure assessment is not appropriate for substances with potential for accumulation in soil. In addition, guidance is lacking for the assessment of effects at higher tiers of the ERA, e.g., for field studies or a tiered effects assessment in the dung compartment.

  16. Risk Factors For Ectopic Pregnancy : A Case Control Study

    Directory of Open Access Journals (Sweden)

    Deshmukh J.S

    1999-01-01

    Full Text Available Research question: Which are the risk factors for ectopic pregnancy . Objective: To study the strength of association between hypothesised risk factors and ectopic pregnancy. Study design: Unmatched case- control study. Setting: Government Medical College, Hospital, Nagpur. Participants: 133 cases of ectopic pregnancy and equal number of controls (non pregnant women admitted to study hospital. Study variables : Pelvic inflammatory diseases, sexually transmitted diseases, IUD use at conception , past use of IUD, prior ectopic pregnancy, OC pills use at the time of conception, past use of OC pills, induced abortion, spontaneous abortion, infertility and pelvic and abdominal surgery. Statistical analysis: Odds ratios & their 95% CI, Pearson’s chi square test, unconditional logistic regression analysis and population attributable risk proportion. Results : Use of IUD at conception, prior ectopic pregnancy , pelvic inflammatory disease, sexually transmitted diseases, infertility, OC pills use at the time of conception, past use of IUD and induced abortion were found to be significantly associated with ectopic pregnancy. Conclusion: Identification of these risk factors for etopic pregnancy shall help in early detection and appropriate management in an individual case and it may help in devising a comprehensive preventive strategy for ectopic pregnancy

  17. Study on Risk of Enterprise' Technology Innovation Based on ISM

    Science.gov (United States)

    Li, Hongyan

    The risk in the process of enterprise' technology innovation is concluted five subsystems: environmental risk, market risk, enterprise capacity risk, project risk and project management risk, 16 risk factors under each subsystem are identified. A Interpretative Structural Modeling(ISM) of of risk factors is established, the relationship and influence levels of them is confirmed, the purpose is to help enterprise assessing risks and taking countermeasure to minimize the potential loss and increase the innovation income.

  18. Risk factors of knee osteoarthritis, WHO-ILAR-COPCORD study

    Directory of Open Access Journals (Sweden)

    Barghamdi M

    2009-01-01

    Full Text Available "nBackground: To evaluate the association between age, sex, BMI, waist/hip ratio, smoking, religion, ethnicity, education and knee osteoarthritis. "nMethods: Eligible subjects were randomly included from participants of Tehran COPCORD study, of whom 480 subjects with knee osteoarthritis were compared to 490 subjects without (case-control study. Using a questionnaire developed by COPCORD group (Asia & Oceania, we enquired about the risk factors of knee osteoarthritis i.e. age, sex, BMI, Waist/Hip ratio, religion, ethnicity, education and smoking. Knee osteoarthritis was defined using ACR criteria. Each knee was unit of analysis using GEE technique to evaluate these associations. "nResults: Age (OR; 1.096; CI95%: 1.091-1.1; P: 0.00 and sex (OR; 2.85; CI95%: 2.49-3.28; P: 0.00 showed significant association with knee osteoarthritis. Overweight (OR; 1.81; CI95%: 1.28-2.55; P: 0.00 and obesity (OR; 3.3; CI95%: 2.34-4.66; P: 0.00 both showed higher risk for knee osteoarthritis. The association between waist/hip ratio and knee osteoarthritis showed an OR of 5.28, CI95%: 0.89-31.44; P: 0.07. However, this association was only borderline significant. People with different religion or ethnicity and smokers had no extra risks for knee osteoarthritis. Higher education is a protective factor for knee osteoarthritis as people who had university education compared to people with no/primary education showed a lower risk for knee osteoarthritis (OR; 0.54; CI95%: 0.38-0.78; P: 0.00. "nConclusions: Our study confirmed that elderly, females, overweight and obese people are at higher risk to develop knee osteoarthritis as found in western societies. Higher education is a protective factor against knee osteoarthritis. Ethnicity, religion and smoking showed no extra risk of knee osteoarthritis.

  19. Severe acute maternal morbidity: study of epidemiology and risk factors

    Directory of Open Access Journals (Sweden)

    Mridu Sinha

    2016-07-01

    Conclusions: Study of risk factors associated with SAMM can provide important contributions to improve quality of available health care system in order to achieve reduction in maternal mortality. [Int J Reprod Contracept Obstet Gynecol 2016; 5(7.000: 2141-2145

  20. Evaluating Risk Awareness in Undergraduate Students Studying Mechanical Engineering

    Science.gov (United States)

    Langdon, G. S.; Balchin, K.; Mufamadi, P.

    2010-01-01

    This paper examines the development of risk awareness among undergraduate students studying mechanical engineering at a South African university. A questionnaire developed at the University of Liverpool was modified and used on students from the first, second and third year cohorts to assess their awareness in the areas of professional…

  1. Premium auctions and risk preferences: an experimental study

    NARCIS (Netherlands)

    Brunner, C.; Hu, A.; Oechssler, J.

    2014-01-01

    In premium auctions, the highest losing bidder receives a reward from the seller. This paper studies the private value English premium auction (EPA) for different risk attitudes of bidders. We explicitly derive the symmetric equilibrium for bidders with CARA utilities and conduct an experimental stu

  2. Studies on the risk assessment of Listeria monocytogenes

    NARCIS (Netherlands)

    Notermans, S.; Dufrenne, J.; Teunis, P.; Chackraborty, T.

    1998-01-01

    Humans are frequently exposed to Listeria monocytogenes, and high numbers may be ingested during consumption of certain types of food. However, epidemiological investigations show that listeriosis is a rare disease. Risk assessment studies using an animal mouse model indicate that almost all L. mono

  3. Teaching Middle School Social Studies: Who is at Risk?

    Science.gov (United States)

    Field, Sherry L.; Wilhelm, Ron; Nickell, Pat; Culligan, John; Sparks, Jan

    2001-01-01

    Focuses on the problem in labeling children "at risk" because it may be detrimental to their futures. Provides examples of two middle school social studies teachers who have adapted their teaching to meet the needs of all classroom learners by getting to know each student personally. (CMK)

  4. Criminal Victimization and Crime Risk Perception: A Multilevel Longitudinal Study

    Science.gov (United States)

    Russo, Silvia; Roccato, Michele; Vieno, Alessio

    2013-01-01

    In a national sample of the Italian population, surveyed four times between October 2002 and January 2007 (N = 2,008), we performed a multilevel longitudinal study aimed at predicting the increase in crime risk perception as a function of three families of independent variables, respectively lying at the within individual level (direct…

  5. Familial risk of venous thromboembolism: a nationwide cohort study

    DEFF Research Database (Denmark)

    Sørensen, H T; Riis, A H; Diaz, L J

    2011-01-01

    Background: Venous thromboembolism has genetic determinants, but population-based data on familial risks are limited. Objectives: To examine the familial risk of venous thromboembolism. Methods: We undertook a nationwide study of a cohort of patients with deep venous thrombosis or pulmonary...... and expected number of venous thromboembolism cases among siblings, using population-specific, gender-specific and age-specific incidence rates. Results: We identified 30 179 siblings of 19 599 cases of venous thromboembolism. The incidence among siblings was 2.2 cases per 1000 person-years, representing...... with pulmonary embolism. Conclusion: Venous thromboembolism has a strong familial component....

  6. Risk for unemployment of cancer survivors: A Danish cohort study

    DEFF Research Database (Denmark)

    Carlsen, Kathrine; Dalton, Susanne Oksbjerg; Diderichsen, Finn;

    2008-01-01

    AIM: To investigate whether cancer survivors are at an increased risk for unemployment after cancer. MATERIALS AND METHODS: A cohort of 65,510 patients who were part of the workforce in the year before diagnosis and a random sample of 316,925 age and gender-matched controls were followed for up...... to 20 years in a longitudinal register-based cohort study. Demographic, socioeconomic and health-related information were obtained through Danish administrative registers. RESULTS: Cancer survivors had a small but significantly increased risk for unemployment following cancer. Stratified analyses showed...

  7. Análisis del ciclo de vida de la ventana de madera

    OpenAIRE

    Vignote Peña, Santiago; Llorente Díaz, Isabel Mª; Martin Rojas, I.; Moro Coco, O.

    2013-01-01

    Se analiza el ciclo de vida de una ventana de madera y se calcula su huella ecológica. Se compara con la bibliografía existente la huella ecológica de la ventana de madera con la de PVC y la de alumnio

  8. Back work ratio of Brayton cycle; La relacion de trabajo de retroceso de un ciclo Brayton

    Energy Technology Data Exchange (ETDEWEB)

    Malaver de la Fuente, M. [Universidad Maritima del Caribe (Venezuela)]. E-mail: mmf_umc@hotmail.com

    2010-07-15

    This paper analyzes the existing relation between temperatures, back work ratio and net work of Brayton cycle, a cycle that describes gas turbine engines performance. The application of computational software helps to show the influence of back work ratio or coupling ratio, compressor and turbine inlet temperatures in an ideal thermodynamical cycle. The results lead to deduce that the maximum value reached in back work ratio will depend on the ranges of maximum and minimal temperatures of Brayton cycle. [Spanish] En este articulo se estudia la relacion que existe entre las temperaturas, la relacion de trabajo de retroceso y el trabajo neto en el ciclo Brayton, que es el ciclo ideal que describe el comportamiento de los motores de turbina de gas. La aplicacion de programas computarizados ayuda a mostrar la influencia de la relacion de trabajo de retroceso o relacion de acoplamiento, la temperatura de entrada al compresor y la temperatura de entrada a la turbina en este ciclo termodinamico ideal. Los resultados obtenidos permiten deducir que el valor maximo que alcanza la relacion de trabajo de retroceso dependera de los limites de temperatura maxima y minima impuestos en el ciclo Brayton.

  9. Study of Systemic Risk Involved in Mutual Funds

    Science.gov (United States)

    Dash, Kishore C.; Dash, Monika

    Systemic risk, may be defined as the risk that contaminates to the whole system, consisting of many interacting agents that fail one after another. These agents, in an economic context, could be firms, banks, funds, or other financial institutions. Systemic risk is a macroscopic property of a system which emerges due to the nonlinear interaction of agents on a microscopic level. A stock market itself is a system in which there are many sub-systems, like Dowjones, Nifty, Sensex, Nasdaq, Nikkei and other market indices in global perspective. In Indian market, subsystems may be like Sensex, Nifty, BSE200, Bankex, smallcap index, midcap index, S&P CNX 500 and many others. Similarly there are many mutual funds, which have their own portfolio of different stocks, bonds etc. We have attempted to study the systemic risk involved in a fund as a macroscopic object with regard to its microscopic components as different stocks in its portfolio. It is observed that fund managers do manage to reduce the systemic risk just like we take precautions to control the spread of an epidemic.

  10. Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies

    DEFF Research Database (Denmark)

    Johnston, Helinor; Pojana, Giulio; Zuin, Stefano

    2013-01-01

    that exist within the assessment of NM risk. We have retrospectively reflected on the findings of completed nanotoxicology studies to consider what progress and advances have been made within the risk assessment of NMs, as well as discussing the direction that nanotoxicology research is taking...... and identifying the limitations and failings of existing research. We have reflected on what commonly encountered challenges exist and explored how these issues may be resolved. In particular, the following is discussed (i) NM selection (ii) NM physico-chemical characterisation; (iii) NM dispersion; (iv......) selection of relevant doses and concentrations; (v) identification of relevant models, target sites and endpoints; (vi) development of alternatives to animal testing; and (vii) NM risk assessment. These knowledge gaps are relatively well recognised by the scientific community and recommendations as to how...

  11. A prospective study of occupation and prostate cancer risk.

    Science.gov (United States)

    Zeegers, Maurice P A; Friesema, Ingrid H M; Goldbohm, R Alexandra; van den Brandt, Piet A

    2004-03-01

    A wide variety of occupations has been associated with prostate cancer in previous retrospective studies. Most attention has been paid to farming, metal working, and the rubber industry. Today, these results cannot be affirmed with confidence, because many associations could be influenced by recall bias, have been inconsistent, or have not been confirmed satisfactory in subsequent studies. This study was conducted to investigate and confirm these important associations in a large prospective cohort study. The authors conducted a prospective cohort study among 58,279 men. In September 1986, the cohort members (55-69 years) completed a self-administered questionnaire on potential cancer risk factors, including job history. Related job codes were clustered in professional groups. These predefined clusters were investigated in 3 time windows: 1) profession ever performed, 2) longest profession ever held, and 3) last profession held at baseline. Follow up for incident prostate cancer was established by linkage to cancer registries until December 1993. A case-cohort approach was used based on 830 cases and 1525 subcohort members. To minimize false-positive results, 99% confidence intervals (99% CI) were calculated. Although moderately decreased prostate cancer risks were found for electricians, farmers, firefighters, woodworkers, textile workers, butchers, salesmen, teachers, and clerical workers, none of the relative risks (RR) were found to be statistically significant. For road transporters, metal workers, and managers, no association with prostate cancer risk was found. Although the RR for railway workers, mechanics, welders, chemists, painters, and cooks was moderately increased, these estimates were not statistically significant. For men who reported to have ever worked in the rubber industry, we found a substantially increased prostate cancer risk, but not statistically significant (RR, 4.18; 99% CI = 0.22-80.45). For policemen, we found a substantial and

  12. Risk perception and choice of place of birth in women with high risk pregnancies: A qualitative study.

    Science.gov (United States)

    Lee, Suzanne; Ayers, Susan; Holden, Des

    2016-07-01

    Objective To examine the perception of risk among a group of women with high risk pregnancies who were either planning to give birth in hospital, or at home despite medical advice to the contrary. The intention was to consider differences and similarities between the groups to examine how perception of risk relates to choice of place of birth. Design Qualitative study using semi-structured interviews. Setting Maternity department in a hospital in South East England. Participants Twenty-six women with high risk pregnancies, at least 32 weeks pregnant. Half were planning hospital births and half homebirths. Measurements and findings Semi-structured interviews to investigate women's understanding and assessment of risk. Results were analysed using thematic analysis. Five themes emerged: understanding of situation; judgement of risk; reassuring factors; impact of risk; and coping with risk. Women from both groups had some understanding of the implications of their medical/obstetric conditions. They displayed concerns about their babies' wellbeing. Women planning homebirths assessed their risks as lower and expressed less concerns than women planning hospital births. Women planning hospital births more frequently described following professional advice. Key conclusions Risk perception is individual and subjective. Women with high risk pregnancies who plan to give birth at home perceive risk differently to women who plan hospital births. Implications for practice Healthcare professionals working with women with high risk pregnancies should be aware of the potential for differences in definitions and perceptions of risk within this group.

  13. The Risk-Stratified Osteoporosis Strategy Evaluation study (ROSE)

    DEFF Research Database (Denmark)

    Rubin, Katrine Hass; Holmberg, Teresa; Rothmann, Mette Juel

    2015-01-01

    The risk-stratified osteoporosis strategy evaluation study (ROSE) is a randomized prospective population-based study investigating the effectiveness of a two-step screening program for osteoporosis in women. This paper reports the study design and baseline characteristics of the study population....... 35,000 women aged 65-80 years were selected at random from the population in the Region of Southern Denmark and-before inclusion-randomized to either a screening group or a control group. As first step, a self-administered questionnaire regarding risk factors for osteoporosis based on FRAX......(®) was issued to both groups. As second step, subjects in the screening group with a 10-year probability of major osteoporotic fractures ≥15 % were offered a DXA scan. Patients diagnosed with osteoporosis from the DXA scan were advised to see their GP and discuss pharmaceutical treatment according to Danish...

  14. Social Amplification of Risk and Crisis Communication Planing - Case Study

    Science.gov (United States)

    Stanciugelu, I.; Frunzaru, V.; Armas, I.; Duntzer, A.; Stan, S.

    2012-04-01

    Risk management has become a dominant concern of public policy and the ability of government to anticipate the strength and focus of public concerns remains weak. The Social Amplification of Risk Framework (SARF) was designed to assist in this endeavor. It aims to facilitate a greater understanding of the social processes that can mediate between a hazard event and its consequences. SARF identifies categories of mediator/moderator that intervene between risk event and its consequences and suggests a causal and temporal sequence in which they act. Information flows first through various sources and then channels, triggering social stations of amplification, initiating individual station of amplification and precipitating behavioral reactions. The International Risk Governance Council Framework is an interdisciplinary and multilevel approach, linking risk management and risk assessment sphere through communication. This study aims to identify categories of mediator/moderator that intervene between the risk event and its consequences, using a survey on earthquake risk perception addressing population of Bucharest city. Romania has a unique seismic profile in Europe, being the country with the biggest surface affected in case of a serious earthquake. Considering the development of the urban area that took place in the last two decades and the growing number of inhabitants, Bucharest is the largest city in Romania and is exposed to extensive damages in case of an earthquake. The sociological survey has been conducted in December 2009 on a representative sample of the Bucharest population aged 18 and over (N=1376) using one stage sampling design. We used a stratified sample method shearing the investigated populations in six layers according to the six sectors of Bucharest. The respondents were selected using random digit dialling method (RDD) and the questionnaires were administered by research staff with computer assisted telephone interviewing method (CATI). The

  15. A influência do ciclo menstrual na flexibilidade em praticantes de ginástica de academia La influencia del ciclo menstrual sobre la flexibilidad en practicantes de gimnasia de academia The influence of the menstrual cycle on the flexibility in practitioners of gymnastics at fitness centers

    Directory of Open Access Journals (Sweden)

    Solange Mattos Melegario

    2006-06-01

    Full Text Available Este estudo teve por objetivo investigar se existem diferenças no grau de flexibilidade nas fases do ciclo menstrual de mulheres adultas jovens praticantes de ginástica de academia. A amostra intencional foi composta de 20 mulheres, com idade de 18 a 35 anos (25,8 ± 6,06, com o ciclo menstrual regular (28 até 32 dias e que não faziam uso de anticoncepcional oral. Dados referentes ao ciclo menstrual e atividade física habitual foram obtidos através da aplicação de um questionário. A flexibilidade foi aferida através da goniometria, utilizando-se oito movimentos, em três fases do ciclo menstrual. Os sujeitos foram submetidos a um teste hormonal, em que foram verificadas as taxas de estrona, estradiol e progesterona. O tratamento estatístico foi feito através de análise descritiva e inferencial (teste de Kolmogorov-Smirnov e ANOVA. Os resultados encontrados demonstraram que não houve diferença significativa (p Este estudio ha tenido por objetivo investigar si existen diferencias en el grado de flexibilidad en las fases del ciclo menstrual de mujeres adultas jóvenes practicantes de gimnasia de academia. La muestra intencional fue compuesta de 20 mujeres, con edades entre 18 a 35 años (25,8 ± 6,06, con ciclo menstrual regular (28 a 32 días y que no hacían uso de anticonceptivo oral. Datos referentes al ciclo menstrual y actividad física habitual fueron obtenidos a través de una encuesta. La flexibilidad fue medida a través de la goniometría, utilizándose ocho movimientos, en tres fases del ciclo menstrual. Los individuos fueron sometidos a un test hormonal, en donde se verificaron la tasa de estrona, estradiol y progesterona. El tratamiento estadístico fue hecho a través del análisis descriptivo y de inferencia (test de Kolmogorov-Smirnov y ANOVA. Los resultados encontrados mostraron que no hubo diferencia significativa (p This study aims to verify if there are differences in the degree of flexibility in the phases of

  16. Influência das diferentes fases do ciclo menstrual na flexibilidade de mulheres jovens

    Directory of Open Access Journals (Sweden)

    André Luiz da Silva Teixeira

    2012-12-01

    Full Text Available INTRODUÇÃO: O ciclo menstrual é o principal responsável por modificações da fisiologia feminina, que pode afetar algumas respostas morfofuncionais. OBJETIVO: Verificar a influência das diferentes fases do ciclo menstrual na flexibilidade de mulheres jovens. MÉTODO: 44 voluntárias divididas em um grupo controle (n = 24, que fazia uso regular de contraceptivos hormonais, e um grupo experimental (n = 20, que não utilizava anticoncepcionais, foram submetidas a três dias de avaliações, uma em cada fase do ciclo menstrual (folicular, ovulatória e lútea. Foram avaliados dados antropométricos (massa corporal, índice de massa corporal, circunferência de cintura e abdômen e de composição corporal (percentual de gordura e massa magra. A flexibilidade foi mensurada através do teste de sentar e alcançar no banco de Wells. Aplicou-se, então, o teste não paramétrico de Mann-Whitney para as comparações intergrupos e o teste de Friedman para a comparação entre as diferentes fases menstruais. Resultados: Não foram encontradas diferenças significativas intra e intergrupos entre as diferentes fases do ciclo (p > 0,05. Foi observada maior variabilidade no grupo controle em comparação ao experimental. CONCLUSÃO: As diferentes fases do ciclo menstrual não interferem na flexibilidade de mulheres jovens, independente do uso de anticoncepcionais hormonais.

  17. Auto-organização e complexidade: o problema do desenvolvimento do ciclo vigília-sono

    Directory of Open Access Journals (Sweden)

    José Roberto Castilho Piqueira

    1998-08-01

    Full Text Available NESTE ARTIGO tenta-se estabelecer algumas interpretações teóricas para os conceitos de auto-organização e complexidade em sistemas biológicos, utilizando-se idéias originárias da Teoria da Informação e da Teoria dos Sistemas Dinâmicos. Além disso, apresenta-se um exemplo de aplicação dos métodos propostos ao problema da caracterização do grau de organização do ciclo vigília-sono em bebês.THIS ARTICLE is a trial on stablishing some theoretical formalisms for the concepts of self-organizing and complex biological systems, using ideas from Information Theory and Dynamical Systems Theory. As an example the organization of the sleep-wake cycle in babies is studied, applying the methods proposed.

  18. Cannabis use and risk of schizophrenia: a Mendelian randomization study.

    Science.gov (United States)

    Vaucher, J; Keating, B J; Lasserre, A M; Gan, W; Lyall, D M; Ward, J; Smith, D J; Pell, J P; Sattar, N; Paré, G; Holmes, M V

    2017-01-24

    Cannabis use is observationally associated with an increased risk of schizophrenia, but whether the relationship is causal is not known. Using a genetic approach, we took 10 independent genetic variants previously identified to associate with cannabis use in 32 330 individuals to determine the nature of the association between cannabis use and risk of schizophrenia. Genetic variants were employed as instruments to recapitulate a randomized controlled trial involving two groups (cannabis users vs nonusers) to estimate the causal effect of cannabis use on risk of schizophrenia in 34 241 cases and 45 604 controls from predominantly European descent. Genetically-derived estimates were compared with a meta-analysis of observational studies reporting ever use of cannabis and risk of schizophrenia or related disorders. Based on the genetic approach, use of cannabis was associated with increased risk of schizophrenia (odds ratio (OR) of schizophrenia for users vs nonusers of cannabis: 1.37; 95% confidence interval (CI), 1.09-1.67; P-value=0.007). The corresponding estimate from observational analysis was 1.43 (95% CI, 1.19-1.67; P-value for heterogeneity =0.76). The genetic markers did not show evidence of pleiotropic effects and accounting for tobacco exposure did not alter the association (OR of schizophrenia for users vs nonusers of cannabis, adjusted for ever vs never smoker: 1.41; 95% CI, 1.09-1.83). This adds to the substantial evidence base that has previously identified cannabis use to associate with increased risk of schizophrenia, by suggesting that the relationship is causal. Such robust evidence may inform public health messages about cannabis use, especially regarding its potential mental health consequences.Molecular Psychiatry advance online publication, 24 January 2017; doi:10.1038/mp.2016.252.

  19. Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe - The EURIKA Study

    Directory of Open Access Journals (Sweden)

    Borghi Claudio

    2011-09-01

    Full Text Available Abstract Background Physicians involved in primary prevention are key players in CVD risk control strategies, but the expected reduction in CVD risk that would be obtained if all patients attending primary care had their risk factors controlled according to current guidelines is unknown. The objective of this study was to estimate the excess risk attributable, firstly, to the presence of CVD risk factors and, secondly, to the lack of control of these risk factors in primary prevention care across Europe. Methods Cross-sectional study using data from the European Study on Cardiovascular Risk Prevention and Management in Daily Practice (EURIKA, which involved primary care and outpatient clinics involved in primary prevention from 12 European countries between May 2009 and January 2010. We enrolled 7,434 patients over 50 years old with at least one cardiovascular risk factor but without CVD and calculated their 10-year risk of CVD death according to the SCORE equation, modified to take diabetes risk into account. Results The average 10-year risk of CVD death in study participants (N = 7,434 was 8.2%. Hypertension, hyperlipidemia, smoking, and diabetes were responsible for 32.7 (95% confidence interval 32.0-33.4, 15.1 (14.8-15.4, 10.4 (9.9-11.0, and 16.4% (15.6-17.2 of CVD risk, respectively. The four risk factors accounted for 57.7% (57.0-58.4 of CVD risk, representing a 10-year excess risk of CVD death of 5.66% (5.47-5.85. Lack of control of hypertension, hyperlipidemia, smoking, and diabetes were responsible for 8.8 (8.3-9.3, 10.6 (10.3-10.9, 10.4 (9.9-11.0, and 3.1% (2.8-3.4 of CVD risk, respectively. Lack of control of the four risk factors accounted for 29.2% (28.5-29.8 of CVD risk, representing a 10-year excess risk of CVD death of 3.12% (2.97-3.27. Conclusions Lack of control of CVD risk factors was responsible for almost 30% of the risk of CVD death among patients participating in the EURIKA Study.

  20. Risk management :A probe and study on forest fires

    Institute of Scientific and Technical Information of China (English)

    YUE Jinzhu; FENG Zhongke; JIANG Wei; YANG Xiaoqin

    2007-01-01

    The subject of risk management is attracting more and more attention around the world.The risk of forest fire disasters should be faced and dealt with for forest fires cannot be avoided.Treating forest fire disasters as a risk management issue promotes important measures and methods for fire fighters to prevent,reduce and control the risks of forest fires.In this paper,the risk concept andrisk connotation as well as the management risks for forest fire suppression are discussed clearly.Issues such as risk judgments,risk analysis,risk control and the assessment of risk,including their contents and corresponding methods are clarified.

  1. Núcleo central e periferia das representações sociais de ciclos de aprendizagem entre professores Centro y periferia de las representaciones sociales de ciclos de aprendizaje entre maestros Core and periphery of social representation cycles between learning teachers

    Directory of Open Access Journals (Sweden)

    Laêda Bezerra Machado

    2010-06-01

    Full Text Available Este artigo identifica as representações sociais de ciclos de aprendizagem entre professores de Recife e suas implicações práticas, demarcando a saliência e estrutura dessas representações. Participaram do estudo 103 professores. O procedimento de coleta utilizado foi a associação livre de palavras. Os dados foram processados pelo software EVOC, que oferece um gráfico com quatro quadrantes onde localizamos o provável núcleo central e sistema periférico da representação social. Os resultados apontam um discurso racionalizado, ou seja, a saliência dessa representação permite afirmar que os docentes, embora na prática critiquem e rechacem os ciclos de aprendizagem, nas suas representações revelam sintonia com a proposta da rede municipal. Sugerimos, portanto, estudos mais densos das práticas cotidianas desses docentes, para depreender aspectos das representações sociais que nos pareceram pouco revelados.El artículo identifica las representaciones sociales de los ciclos de aprendizaje entre los profesores de Recife y sus implicaciones prácticas, señalando la importancia y la estructura de estas representaciones. Los participantes fueron 103 docentes. El procedimiento de recolección utilizado fue la asociación libre de palabras. Los datos fueron procesados por software EVOC, que ofrece un gráfico con cuatro cuadrantes donde localizamos el probable núcleo central y sistema periférico de la representación social. Los resultados muestran un discurso racional, es decir, la importancia de esta representación permite afirmar que los profesores, aunque en la práctica critican y niegan los ciclos de aprendizaje, en sus representaciones muestran de acuerdo con la propuesta de la red municipal. Sugerimos, por lo tanto, los estudios más densos de las prácticas cotidianas de los profesores, para inferir aspectos de las representaciones sociales que nos parezcan poco revelados.This article identifies the social

  2. Risk factors of Cancer Prostate A case control study.

    Science.gov (United States)

    Kamel, Nahed M; Tayel, Eiman S; El Abbady, Ahmed A; Khashab, Sahar S

    2006-01-01

    The purpose of this study is to reveal the different risk factors related to this cancer particularly that there is no agreement about which factors affect the risk. A fishing expedition hospital based case control study was carried out. Cases and controls were identified from the Urology Department of Alexandria Main University Hospital, 2004. All cases diagnosed as having the tumor were included in the case series. For each case the second subject proved to have a negative pathological examination was included in the control group (50).Data collection was carried out blindly using a structured interview schedule. Analysis was applied using Chi-square test, Fisher exact and Student's t-test. Odds Ratios and 95% Confidence Intervals were calculated. Results indicated that regular consumption of sausages was greater among cases than controls (X(2)= 10.19, p= 0.001 and an odds ratio of 5.92 (CI: 1.69-25.99). Also more cases claimed consuming regularly butter and natural ghee than controls (X(2)= 5.47, p= 0.019). The estimate risk was as high as 2.79 (Cl: 1.07-7.33). However regular consumption of vegetables was more encountered among controls than cases (X(2) = 5.005, p= 0.025 where the odds ratio was 0.19 (Cl: 0.02-1.01). Moreover the multiple regression analysis confirmed the results obtained from univariate analysis. The consistency of results of current work as regards sausages and butter with several other research works can support the identification of these specific possible risk factors. Also other research workers pointed out to the protective effect of vegetables. However further research is needed to address other risk factors.

  3. Serum calcium concentration and prostate cancer risk: a multicenter study.

    Science.gov (United States)

    Salem, Sepehr; Hosseini, Mostafa; Allameh, Farzad; Babakoohi, Shahab; Mehrsai, Abdolrasoul; Pourmand, Gholamreza

    2013-01-01

    This study sought to further evaluate the possible effects of serum calcium level on prostate cancer (PC) risk, with considering the age, body mass index (BMI), and sex steroid hormones. Using data from a prospective multicenter study, serum calcium concentration, as well as thorough demographic and medical characteristics, were determined in 194 cases with newly diagnosed, clinicopathologically confirmed PC and 317 controls, without any malignant disease, admitted to the same network of hospitals. Serum total and ionized calcium levels were categorized into tertiles. Multivariate logistic regression model was used to estimate odds ratios (OR) and corresponding 95% confidence intervals (CI) after adjustment for major potential confounders, including age, BMI, smoking, alcohol, education, occupation, marital status, family history of PC, and sex hormones level. The mean serum calcium level (±SD) in case and control groups was 9.22 (±0.46) mg/dl and 9.48 (±0.51) mg/dl, respectively (P < 0.001). After adjustment for mentioned confounders, a significant trend of decreasing risk was found for serum total calcium concentration (OR = 0.27, 95% CI = 0.12-0.59, comparing the highest with the lowest tertile) and ionized calcium (OR = 0.25, 95% CI = 0.10-0.58). An increase of 1 mg/dl in serum calcium level was associated with a significant decrease in PC risk (OR = 0.52; 95% CI = 0.34-0.76). Our findings reveal the inverse association between serum total and ionized concentrations and PC risk, which supports the hypothesis that calcium may protect against PC. Furthermore, no evidence was found regarding age, BMI, and sex steroid hormones to modify the association between serum calcium and PC risk.

  4. Propranolol Reduces Cancer Risk: A Population-Based Cohort Study.

    Science.gov (United States)

    Chang, Ping-Ying; Huang, Wen-Yen; Lin, Cheng-Li; Huang, Tzu-Chuan; Wu, Yi-Ying; Chen, Jia-Hong; Kao, Chia-Hung

    2015-07-01

    β-Blockers have been reported to exhibit potential anticancer effects in cancer cell lines and animal models. However, clinical studies have yielded inconsistent results regarding cancer outcomes and cancer risk when β-blockers were used. This study investigated the association between propranolol and cancer risk.Between January 1, 2000 and December 31, 2011, a patient cohort was extracted from the Longitudinal Health Insurance Database 2000, a subset of the Taiwan National Health Insurance Research Database. A propranolol cohort (propranolol usage >6 months) and nonpropranolol cohort were matched using a propensity score. Cox proportional hazard models were used to estimate the hazard ratio (HR) and 95% confidence intervals (CIs) of cancer associated with propranolol treatment.The study sample comprised 24,238 patients. After a 12-year follow-up period, the cumulative incidence for developing cancer was low in the propranolol cohort (HR: 0.75; 95% CI: 0.67-0.85; P propranolol treatment exhibited significantly lower risks of cancers in head and neck (HR: 0.58; 95% CI: 0.35-0.95), esophagus (HR: 0.35; 95% CI: 0.13-0.96), stomach (HR: 0.54; 95% CI: 0.30-0.98), colon (HR: 0.68; 95% CI: 0.49-0.93), and prostate cancers (HR: 0.52; 95% CI: 0.33-0.83). The protective effect of propranolol for head and neck, stomach, colon, and prostate cancers was most substantial when exposure duration exceeded 1000 days.This study supports the proposition that propranolol can reduce the risk of head and neck, esophagus, stomach, colon, and prostate cancers. Further prospective study is necessary to confirm these findings.

  5. STUDY OF RISK FACTORS AND CLINICAL PROFILE OF ACUTE STROKE

    Directory of Open Access Journals (Sweden)

    Tomar

    2014-05-01

    Full Text Available `INTRODUCTION: Stroke is the third leading cause of death in developed countries after cardiovascular disease and cancer. In India Community Surveys have shown a crude prevalence rate for hemiplegia 200 per 1, 00, 000 population. It accounts for nearly 1.5% of all urban admissions, 4.5 % of all medical and about 20% of neurological cases. AIMS AND OBJECTIVE: Identification of risk factors and evaluation of clinical profile of acute stroke. MATERIAL AND METHOD: INCLUSION CRITERIA: Cases of acute stoke admitted in SGMH hospital were selected for the study. EXCLUSION CRITERIA: Brain injury cases, infective, neoplastic cases producing stroke were excluded. RESULTS: Stroke was more common in male, 58 % patients were male and 42% patients were female. It was more common in 5th and 6th decade. Most common etiology was infarction. Most common risk factor was hypertension followed by smoking. In addition to limb weakness, headache and vomiting were most common presenting symptoms followed by convulsion. These symptoms were more common in hemorrhagic stroke. Right sided hemiplegia was more common than left sided. Middle cerebral artery was involved in majority of cases in atherothrombotic stroke whereas basal ganglion was most common site of bleed in hemorrhagic stroke. Coma and mortality were more in hemorrhagic stroke. CONCLUSION: The risk factors and clinical profile of acute stroke in India are similar to that of Western countries. Common risk factors are hypertension, smoking, diabetes mellitus and hyperlipidemia

  6. Molecular mechanisms underlying noncoding risk variations in psychiatric genetic studies.

    Science.gov (United States)

    Xiao, X; Chang, H; Li, M

    2017-01-03

    Recent large-scale genetic approaches such as genome-wide association studies have allowed the identification of common genetic variations that contribute to risk architectures of psychiatric disorders. However, most of these susceptibility variants are located in noncoding genomic regions that usually span multiple genes. As a result, pinpointing the precise variant(s) and biological mechanisms accounting for the risk remains challenging. By reviewing recent progresses in genetics, functional genomics and neurobiology of psychiatric disorders, as well as gene expression analyses of brain tissues, here we propose a roadmap to characterize the roles of noncoding risk loci in the pathogenesis of psychiatric illnesses (that is, identifying the underlying molecular mechanisms explaining the genetic risk conferred by those genomic loci, and recognizing putative functional causative variants). This roadmap involves integration of transcriptomic data, epidemiological and bioinformatic methods, as well as in vitro and in vivo experimental approaches. These tools will promote the translation of genetic discoveries to physiological mechanisms, and ultimately guide the development of preventive, therapeutic and prognostic measures for psychiatric disorders.Molecular Psychiatry advance online publication, 3 January 2017; doi:10.1038/mp.2016.241.

  7. O ciclo econômico em Kalecki, Schumpeter e seus intérpretes : Possas e Minsky

    OpenAIRE

    Diogo Daniel Bandeira de Albuquerque

    2015-01-01

    Resumo: A presente dissertação tem como objetivo apresentar as teorias do ciclo econômico elaboradas por Kalecki e Schumpeter, expor as suas diferenças e destacar seus pontos de convergência. Por meio de uma análise sistemática das obras destes autores, se averiguou que eles se distinguiram no enfoque sobre o tema. Kalecki apresentou uma teoria do ciclo baseada em um estudo sobre a demanda, enquanto Schumpeter demonstrou o ciclo por meio da sua análise sobre a oferta. Esses autores serviram d...

  8. Inducción de ciclos estrales en la perra: actualización bibliográfica

    OpenAIRE

    2006-01-01

    La inducción de ciclos estrales puede implementarse en aquellas perras con diagnóstico de intervalos interestrales prolongados no relacionados con enfermedad subyacente. Así mismo la inducción de ciclos estrales puede también utilizarse para lograr nacimientos en épocas del año en que aumenta notablemente la demanda de cachorros en el mercado. Por otra parte la inducción y sincronización de ciclos son prerrequisitos para los programas de transferencia embrionaria. Los métodos comunicados para...

  9. Risk policies and risk perceptions: a comparative study of environmental health risk policy and perception in six European countries

    NARCIS (Netherlands)

    Bröer, C.; Moerman, G.; Spruijt, P.; van Poll, R.

    2014-01-01

    This paper explores the influence that health risk policies have on the citizens’ perceptions of those health risks. Previously, detailed mixed methods research revealed that noise annoyance policies shaped noise perception. This idea is now applied to nine different environmental health risks in si

  10. Anybody can do Value at Risk: A Nonparametric Teaching Study

    Directory of Open Access Journals (Sweden)

    Robert J Powell

    2012-03-01

    Full Text Available Value at Risk (VaR has become a benchmark methodology among investors and banks for measuring market risk. Commercially available modelling packages can be both expensive and inflexible, thereby restricting their use by academic researchers and teachers. Usingnonparametric methodology, this paper provides a step-by-step teaching study on how to use Excel to construct a VaR spreadsheet for an individual asset as well as for a portfolio. This can benefit financial modelling teachers by providing them with a readily useable teaching study on how to model VaR, as well as benefit researchers by showing them how to construct an inexpensive and flexible VaR model.

  11. Infections as risk factor for autoimmune diseases - A nationwide study

    DEFF Research Database (Denmark)

    Nielsen, Philip Rising; Kragstrup, Tue Wenzel; Deleuran, Bent Winding;

    2016-01-01

    Viruses, bacteria and other infectious pathogens are the major postulated environmental triggers of autoimmunity. In the present nation-wide study we describe the association between infections and 29 autoimmune diseases. We used the Danish Civil Registration System to identify 4.5 million persons...... born between 1945 and 2000. Information on infections and autoimmune diseases was obtained from the Danish Hospital Register. The cohort was followed from 1977 to 2012. Incidence rate ratios for developing an autoimmune disease were estimated using poisson regression. We found an association between...... hospital admission for an infection and 29 autoimmune diseases. This study shows that infections are risk factors for a broad spectrum of autoimmune diseases in a dose-response and temporal manner, in agreement with the hypothesis that infections are an environmental risk factor contributing...

  12. RELAÇÕES HÍDRICAS EM DOIS HÍBRIDOS DE MILHO SOB DOIS CICLOS DE DEFICIÊNCIA HÍDRICA WATER RELATIONS IN TWO HYBRIDS OF CORN UNDER TWO CYCLES OF WATER STRESS

    Directory of Open Access Journals (Sweden)

    CARLOS PIMENTEL

    1999-11-01

    Full Text Available Neste trabalho foram estudadas as relações hídricas de dois híbridos de milho (Zea mays L., em casa de vegetação: o IAC 8222 (híbrido com tolerância ambiental e o DINA 10 (híbrido comum; submetidos a um ou a dois ciclos de estresse, aos 30 e 46 DAP. O IAC 8222 manteve o potencial hídrico de folha (psihf superior ao do DINA no primeiro ciclo de estresse e no segundo ciclo, em plantas que sofreram os dois ciclos (com endurecimento, no sexto e último dia de deficiência hídrica, não havendo diferenças em relação ao conteúdo hídrico relativo (CHR entre os híbridos. Houve um aumento da concentração de açúcares solúveis e de aminoácidos com a deficiência hídrica, sem diferenças entre os híbridos no primeiro ciclo de déficit hídrico, e com aumento significativo somente na concentração de aminoácidos no DINA 10 submetido aos dois ciclos, no último dia do segundo ciclo. A concentração de K+ não variou nem com os ciclos nem entre híbridos. Portanto, só houve diferenças na acumulação de solutos osmóticos entre os híbridos, quanto ao teor de aminoácidos no DINA 10 submetido aos dois ciclos, no segundo ciclo. Contudo, o IAC 8222 manteve o seu psihf alto, podendo ter promovido um ajuste do coeficiente de extensibilidade de parede, que foi acentuado com o endurecimento.A study was conducted to evaluate the water relations of two corn (Zea mays L. hybrids in a greenhouse experiment: IAC 8222 (hybrid adapted to environmental stress and DINA 10 (common hybrid, under one or two cycles of water stress applied at 30 and 46 days after sowing. During the first water deficit cycle, and at the second cycle for plants submitted to both cycles, the leaf water potential (psihf of IAC 8222 was higher than the psihf of DINA 10, at the 6th and last day of water stress, with no difference for the relative water content (CHR between the hybrids. The soluble sugars and amino acids accumulated during the water stress, but no

  13. Measuring adolescents’ exposure to victimization: The Environmental Risk (E-Risk) Longitudinal Twin Study

    Science.gov (United States)

    Fisher, Helen L.; Caspi, Avshalom; Moffitt, Terrie E.; Wertz, Jasmin; Gray, Rebecca; Newbury, Joanne; Ambler, Antony; Zavos, Helena; Danese, Andrea; Mill, Jonathan; Odgers, Candice L.; Pariante, Carmine; Wong, Chloe C.; Arseneault, Louise

    2016-01-01

    This paper presents mutlilevel findings on adolescents’ victimization exposure from a large longitudinal cohort of twins. Data were obtained from the Environmental Risk (E-Risk) Longitudinal Twin Study, an epidemiological study of 2,232 children (1,116 twin pairs) followed to 18 years of age (with 93% retention). To assess adolescent victimization we combined best practices in survey research on victimization with optimal approaches to measuring life stress and traumatic experiences, and introduce a reliable system for coding severe victimization. One in three children experienced at least one type of severe victimization during adolescence (crime victimization, peer/sibling victimization, internet/mobile phone victimization, sexual victimization, family violence, maltreatment, or neglect), and most types of victimization were more prevalent amongst children from low socioeconomic backgrounds. Exposure to multiple victimization types was common, as was re-victimization; over half of those physically maltreated in childhood were also exposed to severe physical violence in adolescence. Biometric twin analyses revealed that environmental factors had the greatest influence on most types of victimization, while severe physical maltreatment from caregivers during adolescence was predominantly influenced by heritable factors. The findings from this study showcase how distinct levels of victimization measurement can be harmonized in large-scale studies of health and development. PMID:26535933

  14. Assessing fluvial flood risk in urban environments: a case study

    Directory of Open Access Journals (Sweden)

    Longo Elisa

    2016-01-01

    Full Text Available Nowadays, floods are among the most impactful calamities regarding costs. Looking at the natural hazards damage data collected in the International Disaster Database (EM-DAT, it is observable a significant increase over the past four decades of both frequency of floods and associated costs. Similarly, dramatic trends are also found by analyzing other types of flood losses, such as the number of people affected by floods, homeless, injured or killed.To deal with the aforementioned rise of flood risk, more and more efforts are being made to promote integrated flood risk management, for example, the Flood Directive 2007/60/EC. The main goals of this research are the estimation of flood damages using the KULTURisk methodology and the comparing of the projected costs with the observed one. The case study is the 2002 flood in Eilenburg. According to KULTURisk methodology, two major classes of data are considered to evaluate flood risk damage: hydraulic data as regards Hazard and economic information to assess Exposure and Vulnerability This study shows the possibility to extend the lesson learned with the Eilenburg case study in other similar contexts.

  15. Risk factors in pediatric asthmatic patients. Cases and control studies.

    Directory of Open Access Journals (Sweden)

    Rafael Alejandro Gómez Baute

    2003-04-01

    Full Text Available Background: Asthma constitutes the first disease among chronic diseases in children. The morbid-mortality promoted to continue being elevated in spite of the new therapies. For this reason it is a disease with high priority for investigation in pediatric ages. Method: A control and case group study was carried out. The samples was composed by 72 asthmatic children from three General Comprehensive doctor offices from Palmira health area located in Cienfuegos Province, Cuba; and a control group of 72 children apparently healthy from the same population. A questionnaire with the different risk variables was elaborated. Odds ratio technique was used to estimate the risk. Results: low weight at birth, family history of asthma, brochiolitis antecedent and the excessive usage of antibiotics in children under 1 year old were the main risks found. Conclusions: It is conclusive that the exposure to home allergen plus a genetic favorable factor, the prematurity, and brochiolitis constituted the most outstanding elements to suffer from asthma in the population studied.

  16. Abrasive blasting agents: designing studies to evaluate relative risk.

    Science.gov (United States)

    Hubbs, Ann; Greskevitch, Mark; Kuempel, Eileen; Suarez, Fernando; Toraason, Mark

    Workers exposed to respirable crystalline silica used in abrasive blasting are at increased risk of developing a debilitating and often fatal fibrotic lung disease called silicosis. The National Institute for Occupational Safety and Health (NIOSH) recommends that silica sand be prohibited as abrasive blasting material and that less hazardous materials be used in blasting operations. However, data are needed on the relative risks associated with exposure to abrasive blasting materials other than silica. NIOSH has completed acute studies in rats (Hubbs et al., 2001; Porter et al., 2002). To provide dose-response data applicable to making recommendation for occupational exposure limits, NIOSH has collaborated with the National Toxicology Program (NTP) to design longer term studies with silica substitutes. For risk assessment purposes, selected doses will include concentrations that are relevant to human exposures. Rat lung burdens achieved should be comparable to those estimated in humans with working lifetime exposures, even if this results in "overloading" doses in rats. To quantify both dose and response, retained particle burdens in the lungs and lung-associated lymph nodes will be measured, as well as biochemical and pathological indices of pulmonary response. This design will facilitate assessment of the pulmonary fibrogenic potential of inhaled abrasive blasting agents at occupationally relevant concentrations.

  17. Risk

    Science.gov (United States)

    Barshi, Immanuel

    2016-01-01

    Speaking up, i.e. expressing ones concerns, is a critical piece of effective communication. Yet, we see many situations in which crew members have concerns and still remain silent. Why would that be the case? And how can we assess the risks of speaking up vs. the risks of keeping silent? And once we do make up our minds to speak up, how should we go about it? Our workshop aims to answer these questions, and to provide us all with practical tools for effective risk assessment and effective speaking-up strategies..

  18. Study on risk measurement about ammunition-rocket system

    Institute of Scientific and Technical Information of China (English)

    Gu Xiaohui; Zhao Youshou

    2005-01-01

    Modern ammunition-rocket system is a complicated multidisciplinary system. During its development,undetermined factors will bring many risks. This paper elaborates the importance of risk analysis approach to ammunition-rocket system development and analyses various methods of risk analysis and estimation. Combined with practical situation of weapon system development, the risk measurement function with characteristics of risk preference is given provided that the risk preference characteristic of behavior maker is risk neutral of fixed constant. The development risk analysis based on risk measurement function enables effective risk decision to be made on the basis of quantified risk.Taking anti-helicopter intelligent mine warhead as an example, the paper verifies the efficiency of the method and shows that it has a scientific and practical value.

  19. El campamento @PlzaResistencia en el ciclo de protestas en Venezuela 2014

    Directory of Open Access Journals (Sweden)

    Iria Puyosa

    2016-02-01

    Full Text Available El artículo analiza el caso del campamento estudiantil de protesta Plaza de la Resistencia, instalado en Caracas durante los meses de abril y mayo de 2014, en el contexto del ciclo de protestas registrado en Venezuela. Se revisan los factores contextuales antecedentes del ciclo de protestas y se explora la aplicabilidad en este caso de diez dinámicas identificadas como fundamentales en los movimientos sociales en red. Asimismo, se hace un análisis de redes del usuario Twitter @PlzaResistencia que sirvió para la comunicación política autónoma y para la propagación de las consignas de los campistas.

  20. Estudio termoeconómico de diferentes configuraciones de ciclo combinado integrado con una planta solar

    Directory of Open Access Journals (Sweden)

    María Dolores Durán García

    2014-01-01

    Full Text Available Se presenta el análisis termoeconómico de una planta de ciclo combinado integrada con una planta solar de canal parabólico, considerada como una sección de la caldera de recuperación de calor, con el objetivo de conseguir un diseño óptimo al determinar los parámetros de diseño optimizados para ambos sistemas. Se aplica una metodología empleada en trabajos previos para la optimización de ciclos combinados, pero ahora con una planta solar. Como resultado, a partir de un análisis de sensibilidad, se obtiene el desempeño de varias configuraciones bajo diferentes condiciones de radiación solar.

  1. O trabalho de projeto como metodologia no 1º Ciclo do Ensino Básico

    OpenAIRE

    Fernandes, Sónia

    2014-01-01

    O presente relatório pretende contribuir para uma reflexão em torno do trabalho de projeto como metodologia no 1° ciclo do ensino básico. O trabalho teve como suporte metodológico uma abordagem qualitativa e interpretativa, tendo como registo de dados as notas de campo e fotografias recolhidas no período de estágio na Escola Básica do 1° Ciclo António Rebelo de Andrade, na valência do 1° ano do ensino básico. A investigação ação foi a linha orientadora, através da qual foi possível desenvolve...

  2. Ingeniería del conocimiento: Análisis de ciclos de gas

    OpenAIRE

    Gago, Luis Alberto; Beraudo, Vanina; Stark, Natalia

    2008-01-01

    En el marco de la investigación que se centra en estudiar los roles asignados al trabajo práctico, al trabajo de laboratorio, y a los experimentos en la cátedra de Termodinámica, materia de formación básica en ingeniería, se pretende aplicar y extender la funcionalidad de un sistema experto capaz de determinar la factibilidad de funcionamiento de una máquina térmica desde el punto de vista termodinámico, mediante el análisis del diseño de un ciclo de potencia, el ciclo Joule Brayton; y ofrece...

  3. Strategic risk assessment: A case study of climate change

    Energy Technology Data Exchange (ETDEWEB)

    Beer, T. [CSIRO, Mordialloc, Victoria (Australia). Div. of Atmospheric Research

    1996-12-31

    The philosophical basis for the on-going international and Australian action on climate change is the precautionary principle. The version of this relevant to Australia is that agreed to by the Australian States and by the Commonwealth of Australia as expressed in the Inter-Governmental Agreement on the Environment (IGAE). This study addresses the following questions: 1. What form of assessment of the risk-weighted consequences of climate change has been undertaken, as required under the precautionary principle? This paper claims that the IPCC process constitutes the risk-weighted assessment that is needed to justify the use of the precautionary principle. 2. Reducing the risk due to climate change requires actions on the basis of some combination of environmental integrity, equity, and economic efficiency as measured by cost-benefit analysis. Is the concept of intergenerational equity consistent with cost-benefit analysis? This paper claims that the problems of valuation over future time-scales, which may range from decades to centuries, make it difficult to apply cost-benefit analysis to the problem.

  4. Risk factor for phlebitis: a questionnaire study of nurses' perception

    Directory of Open Access Journals (Sweden)

    Dragana Milutinović

    2015-08-01

    Full Text Available AbstractObjectives: to assess nurses' perceptions of risk factors for the development of phlebitis, with a special focus on the perception of phlebitic potentials of some infusion medications and solutions.Method: a cross-sectional questionnaire study, which included a sample of 102 nurses.Results: Nurses recognized some factors that may reduce the incidence of phlebitis; however, more than half of the nurses were unaware that the material and diameter of the cannula can affect the incidence rate of phlebitis. Furthermore,underlying disease and high pH of medications or solutions were identified as potential risk factors, whereas low pH and low osmolality were not. Nurses identified Vancomycin and Benzylpenicillin antibiotics with the strongest phlebitic potential. Among other medications and intravenous fluids, Aminophylline, Amiodaronehydrochloride and Potassium chloride 7.4% were identified as potentially causing phlebitis.Conclusion: predisposing factors for phlebitis relating to patients and administered therapy were identified by nurses, while some cannula related risk factors, in particular its physicochemical properties and the time for cannula replacement, were not fully perceived.

  5. Risk factors for hip fracture in European women: the MEDOS Study. Mediterranean Osteoporosis Study.

    Science.gov (United States)

    Johnell, O; Gullberg, B; Kanis, J A; Allander, E; Elffors, L; Dequeker, J; Dilsen, G; Gennari, C; Lopes Vaz, A; Lyritis, G

    1995-11-01

    The aims of this study were to determine common international risk factors for hip fracture in women aged 50 years or more. We studied women aged 50 years or more who sustained a hip fracture in 14 centers from Portugal, Spain, France, Italy, Greece, and Turkey over a 1-year period. Women aged 50 years or more selected from the neighborhood or population registers served as controls. Cases and controls were interviewed using a structured questionnaire on work, physical activity, exposure to sunlight, reproductive, history and gynecologic status, height, weight, mental score, and consumption of tobacco, alcohol, calcium, coffee, and tea. Significant risk factors identified by univariate analysis included low body mass index (BMI), short fertile period, low physical activity. lack of sunlight exposure, low milk consumption, no consumption of tea, and a poor mental score. No significant adverse effects of coffee or smoking were observed. Moderate intake of spirits was a protective factor in young adulthood, but otherwise no significant effect of alcohol intake was observed. For some risks, a threshold effect was observed. A low BMI and milk consumption were significant risks only in the lowest 50% and 10% of the population, respectively. A late menarche, poor mental score, low BMI and physical activity, low exposure to sunlight, and a low consumption of calcium and tea remained independent risk factors after multivariate analysis, accounting for 70% of hip fractures. Excluding mental score and age at menarche (not potentially reversible), the attributable risk was 56%. Thus, about half of the hip fractures could be explained on the basis of the potentially reversible risk factors sought. In contrast, the use of risk factors to "predict" hip fractures had moderate sensitivity and specificity. We conclude that variations in lifestyle factors are associated with significant differences in the risk of hip fracture, account for a large component of the total risk, and may

  6. Una teoría del ciclo económico

    Directory of Open Access Journals (Sweden)

    Tolosa B. José

    1984-06-01

    Full Text Available El objetivo central de este articulo es plantear un modelo de carácter explicativo referente a las fluctuaciones económicas que sea aplicable a un país con las características de la economía colombiana. Se parte de las formulaciones expuestas por Michal Kalecki en sus diversos estudios sobre el ciclo, superando sus limitantes y elaborando un modelo coherente que cumpla con los objetivos propuestos.

  7. A organização do ensino fundamental em ciclos: algumas questões

    Directory of Open Access Journals (Sweden)

    Ocimar Munhoz Alavarse

    2009-01-01

    Full Text Available En el artículo son problematizados algunos de los aspectos relacionados a la organización de la educación básica en ciclos, partiéndose de iniciativas en materia de educación de redes públicas y de la literatura sobre el tema. La implantación de los ciclos, con diferencias de diversos órdenes, se ha intensificado con la Ley de Directrices y Bases de 1996 y se presenta como una alternativa a la organización de la enseñanza por grados y al fracaso escolar, especialmente por cuenta de las altas tasas de reprobación (repetición y del bajo rendimiento académico de los estudiantes brasileños, y también es acompañada por una fuerte resistencia y controversia. Desde la perspectiva de la democratización de la escuela, se enfoca los retos de la igualdad de resultados, como la profundización de la igualdad de oportunidades, lo que incluye la tensión sobre los años de estudio y la repetición de grado como expediente pedagógico, con énfasis en las metas educativas y las implicaciones pedagógicas que los ciclos impondrían. Sin embargo, si los ciclos no pueden ser asociados a la disminución de la calidad de la educación, se considera que, a pesar de su enorme potencial democrático, todavía no fueron alcanzados los objetivos propuestos con su adopción.

  8. Enhancers and Inhibitors of Teacher Risk Taking: A Case Study.

    Science.gov (United States)

    Ponticell, Judith A.

    2003-01-01

    Examined teacher risk taking during the development of a school-within-a-school program in a Professional Development School, targeting sophomores at high risk for dropping out. Findings indicated that a psychology of risk-taking behavior provided a useful lens for understanding teacher risk-taking in this context and that the three essential…

  9. Credit risk management: a study on risk integration in the bank lending process

    NARCIS (Netherlands)

    Sleddens, Linda Elsa Wilhelmina

    2011-01-01

    Credit risk management has been a topic much written about in the last decade. Substantial credit risk losses can undermine the stability of the bank. Both banks and national bank supervisors have realized the need to invest in credit risk management. Partly driven by regulations such as the Basel I

  10. A Study Of Risk Factors For Low Birth Weight

    Directory of Open Access Journals (Sweden)

    Deswal B S

    1999-01-01

    Full Text Available Research question: What is the extent of low weight babies born in hospitals and its association with some maternal factors? Objectives: 1. To find an overall prevalence of low birth weight babies amongst hospital births in Meerut city. 2. To identify and quantify the effects of some risk factors for low birth weight. Setting: District women Hospital of Meerut city of western U.P. Study Design: Hospital based matched case-control study. Sample size: 491 low birth weight babies as ‘cases’ and an equal number of babies of normal birth weight in ‘control’ group matched for maternal age, sex of baby, birth order and institution of delivery. Study variables: Socio-economic Status: maternal biological factors including obstetric history: antenatal factors: nutritional factors: history of abortion: toxaemia of pregnancy etc. Results: Overall proportion of low birth weight babies was found to be 21.8% amongst hospital live births and 30.9% born to mothers aged below 30 years of age. Low maternal weight, under nutrition, lack of antenatal care, short inter-pregnancy interval, toxacmia of pregnancy were independent factors increasing the risk of low birth weight significantly. Conclusions: The study suggested that a substantial proportion of low birth weight babies can be averted by improving maternal nutritional status including anemic condition, birth spacing and proper antenatal care.

  11. Retinopathy of prematurity and risk factors: a prospective cohort study

    Directory of Open Access Journals (Sweden)

    Angell Linda

    2005-06-01

    Full Text Available Abstract Background Increased survival of extremely low birth infants due to advances in antenatal and neonatal care has resulted in a population of infants at high risk of developing retinopathy of prematurity (ROP. Therapeutic interventions include the use of antenatal and postnatal steroids however, their effects on the severity of ROP is in dispute. In addition, it has not been investigated whether severe ROP is due to therapeutic interventions or due to the severity of illness. The aim of the present study was to assess the association between the incidence of severe retinopathy of prematurity (greater than stage 2 – International classification of ROP and mechanical ventilation, oxygen therapy, gestational age, antenatal and postnatal steroids in extremely low birth weight infants. Methods Neonates admitted to the neonatal intensive care unit in Lansing, Michigan, during 1993–2000 were followed to determine factors influencing the development of severe retinopathy of prematurity. Ophthalmologic examinations were started at 6 weeks and followed until resolution. We used logistic regression to estimate the relative risk (odds ratio associated with risk factors of ROP. Results Of the neonates with ≤ 1500 g birth weight, admitted to the neonatal intensive care unit, 85% (616/725 survived. Severe retinopathy of prematurity was detected in 7.8% of 576 neonates who had eye examinations. Neonates of lower gestational age (≤ 25 weeks and 26–28 weeks had an increased odds ratio of 8.49 and 3.19 for the development of severe retinopathy of prematurity, respectively, compared to those 29 weeks and older. Late postnatal steroid treatment starting after 3 weeks of life showed 2.9-fold increased odds ratio, in particular administration for two weeks and more (OR: 4.09, 95% CI: 1.52–11.03. With increasing antenatal steroids courses the risk of severe retinopathy of prematurity decreased, however, it was not significant. Lower gestational age

  12. Tecnología, ingeniería y ciclos de formación

    Directory of Open Access Journals (Sweden)

    Mirna Jirón Popova

    2014-04-01

    Full Text Available Este artículo presenta parte de los resultados de la investigación La formación tecnológica en Colombia en el ámbito de la universidad pública, particularmente en la Universidad Distrital Francisco José de Caldas, que fue una de las instituciones observadas. En este artículo se exponen los acontecimientos que se suceden desde la ins-titucionalización de la Facultad Tecnológica, con miras a ofrecer Educación Superior Tecnológica a sectores desfavorecidos de la población del Distrito Capital. Se hace especial énfasis en aspectos relacionados con las tensiones entre resistir o adaptarse a lo establecido en los dispositivos de control; coyuntura que finalmente determina que la facultad trasforme su propuesta original de Educación Tecnológica por Ciclos, hacia una de Formación de Ingenieros por Ciclos y, posteriormente, por la Formación de Ingenieros por Ciclos Propedéuticos.

  13. A contribuição das teorias do ciclo de vida organizacional para a pesquisa em contabilidade gerencial

    Directory of Open Access Journals (Sweden)

    Karine Lima de Carvalho

    2010-08-01

    Full Text Available Este trabalho objetiva caracterizar, em uma perspectiva teórica, as contribuições das teorias do ciclo de vida organizacional sobre a pesquisa em contabilidade gerencial. Além disso, levanta os principais autores, as instituições e os países vinculados à pesquisa sobre ciclo de vida organizacional. É desenvolvida uma análise bibliométrica por meio da base de dados ProQuest®. De um total de 22 trabalhos sobre ciclo de vida, seis utilizam como base teórica o ciclo de vida organizacional e apresentam contribuição para a pesquisa em contabilidade gerencial. Conclui-se que o sistema de contabilidade gerencial sofre variações à medida que fatores configuracionais internos e externos da empresa se modificam ao longo das diferentes fases do ciclo de vida organizacional. É evidenciada a existência de uma concentração de trabalhos sobre as principais teorias de ciclo de vida organizacional em universidades do Canadá. Principalmente, em razão do elevado número de citações dos trabalhos desenvolvidos por Danny Miller (École des Hautes Etudes Commerciales e Peter Friesen (Faculty of Management, MacGill University.

  14. Bankruptcy Risk in IFRS Era. Case Study on BSE Companies

    Directory of Open Access Journals (Sweden)

    Valentin BURCA

    2013-12-01

    Full Text Available The path of international accounting convergence is, unanimously accepted by all decision makers of the international financial reporting environment, as being the best solution towards reducing differences in international accounting. The idea of core standards is embraced by our country, too, the proof being the last legislative changes in Romanian accounting framework. This study aims to highlight a small part of the economic consequences of the decision to extend the mandatory use of IFRS standards to the statutory financial statements, also. More exactly we will underline the changes registered at the level of bankruptcy risk measureson a samples of companies listed on BSE.

  15. Indian studies on genetic polymorphisms and cancer risk

    Directory of Open Access Journals (Sweden)

    A Bag

    2012-01-01

    Full Text Available Genetic influences on cancer development have been extensively investigated during the last decade following publication of human genome sequence. The present review summarizes case-control studies on genetic polymorphisms and cancer risk in Indians. It is observed that the most commonly studied genes in the Indian population included members of phase I and phase II metabolic enzymes. Other than these genes, genetic polymorphisms for cell cycle and apoptosis-related factors, DNA repair enzymes, immune response elements, growth factors, folate metabolizing enzymes, vitamin/hormone receptors, etc., were investigated. Several studies also evidenced a stronger risk for combined genotypes rather than a single polymorphism. Gene-environment interaction was also found to be a determining factor for cancer development in some experiments. Data for single polymorphism and single cancer type, however, was insufficient to validate an association. It appears that much more experiments involving larger sample size, cross-tabulating genetic polymorphisms and environmental factors are required in order to identify genetic markers for different cancers in Indian populations.

  16. Variabilidad del intervalo de ciclo de las taquicardias ventriculares con igual morfología inducidas en estudio electrofisiológico

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    Abdel J. Fuenmayor

    2004-01-01

    Full Text Available Introducción: La determinación de la variabilidad espontánea del intervalo de ciclo de las taquicardias ventriculares es fundamental para interpretar los efectos de tratamientos y para programar dispositivos anti-taquicardia. Objetivo: Estudiar la variabilidad espontánea del intervalo de ciclo de las taquicardias ventriculares producidas por re-entrada. Métodos: Incluimos 22 pacientes (12 varones de 52 + 18 años de edad, en quienes se indujeron 121 taquicardias ventriculares monomórficas sostenidas. Las taquicardias inducidas en un mismo paciente tenían la misma morfología y eran producidas por re-entrada. Resultados: En promedio, las taquicardias ventriculares tenían un intervalo de ciclo de 318 + 39 milisegundos (mseg. La desviación típica del promedio de los intervalos de ciclo de las taquicardias ventriculares de igual morfología inducidas en cada paciente (variación inter-taquicardia fue 10,91 + 9,63 mseg. La diferencia promedio entre el R-R máximo y el R-R mínimo (variación inter-taquicardia fue de 26,15 mseg. La variación intra-taquicardia (desviación típica de los 10 ciclos que fueron promediados fue de 5,78 + 2,40 mseg (2,58 - 15,05. El sexo, la etiología y la edad no determinaron diferencias en la frecuencia cardíaca durante e la taquicardia. Conclusión: En este grupo de pacientes, las taquicardias ventriculares de re-entrada originadas en un mismo circuito y en un mismo paciente muestran poca variación del intervalo de ciclo. Esta estabilidad relativa debe tenerse presente al considerar efectos terapéuticos, programar dispositivos anti-taquicardia y estudiar los factores relacionados con la variabilidad misma.Introduction: Th e spontaneous variability in ventricular tachycardia cycle length should be known for the proper assessment of pharmacological treatment and anti-tachycardia devices programming. Objective: To assess the ventricular tachycardia (VT rate variability of patients with re-entrant VTs induced

  17. An empirical study for ranking risk factors using linear assignment: A case study of road construction

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    Amin Foroughi

    2012-04-01

    Full Text Available Road construction projects are considered as the most important governmental issues since there are normally heavy investments required in such projects. There is also shortage of financial resources in governmental budget, which makes the asset allocation more challenging. One primary step in reducing the cost is to determine different risks associated with execution of such project activities. In this study, we present some important risk factors associated with road construction in two levels for a real-world case study of rail-road industry located between two cities of Esfahan and Deligan. The first group of risk factors includes the probability and the effects for various attributes including cost, time, quality and performance. The second group of risk factors includes socio-economical factors as well as political and managerial aspects. The study finds 21 main risk factors as well as 193 sub risk factors. The factors are ranked using groups decision-making method called linear assignment. The preliminary results indicate that the road construction projects could finish faster with better outcome should we carefully consider risk factors and attempt to reduce their impacts.

  18. Cardiometabolic Risk among African-American Women: A Pilot Study

    Science.gov (United States)

    Appel, Susan J.; Oster, Robert A.; Floyd, Natalie A.; Ovalle, Fernando

    2010-01-01

    Objective To determine the associations of the Homeostatic Model of Assessment-insulin resistance (HOMA-ir), acanthosis nigricans, high sensitivity C-reactive protein (hs-CRP), and plasminogen activator inhibitor-1 (PAI-1) with two of the commonly used definitions of the metabolic syndrome (Adult Treatment Panel III {ATP III} and International Diabetes Federation {IDF}) among reproductive age healthy free living African-American women. Methods A pilot study with a cross-sectional design examined 33 African-American women aged 20 to 46 (mean 31.24, +/- 7.25), for the presence of metabolic syndrome determined by ATP III and IDF criteria, insulin resistance (HOMA-ir and/or acanthosis nigricans), degree of inflammation (hs-CRP) and presence of dysfibrinolysis (PAI-1). Results HOMA-ir identified insulin resistance in 27 (81.8%) of the women, whereas the presence of acanthosis nigricans indicated that 16 (48 %) of these women manifested insulin resistance. Metabolic syndrome was found in 7 women (21.2 %) by ATP III or 9 (27.3 %) by IDF criteria. Bivariate correlations showed associations between HOMA-ir and waist circumference, body mass index (BMI), acanthosis nigricans, the ATP III and IDF definitions for metabolic syndrome. PAI-1 was significantly correlated with waist circumference, BMI, fasting glucose, HOMA-ir, and ATP III. Both HOMA-ir and PAI-1 were significantly and negatively correlated with HDL-C. hs-CRP was significantly correlated with BMI and 2-hour post glucose. Conclusion Both dysfibrinolysis (PAI-1 levels) and insulin resistance (HOMA-ir) when individually regressed on the ATP III definition of metabolic syndrome explained 32 % and 29% of the respective variance. The addition of HOMA-ir measurement may significantly improve early recognition of cardiometabolic risk among reproductive age African-American women who have not yet met the criteria for the ATP III or IDF definitions of the metabolic syndrome. Likewise, acanthosis nigricans is potentially a

  19. Risk factors for hip fracture in men from southern Europe: the MEDOS study. Mediterranean Osteoporosis Study.

    Science.gov (United States)

    Kanis, J; Johnell, O; Gullberg, B; Allander, E; Elffors, L; Ranstam, J; Dequeker, J; Dilsen, G; Gennari, C; Vaz, A L; Lyritis, G; Mazzuoli, G; Miravet, L; Passeri, M; Perez Cano, R; Rapado, A; Ribot, C

    1999-01-01

    The aims of this study were to identify risk factors for hip fracture in men aged 50 years or more. We identified 730 men with hip fracture from 14 centers from Portugal, Spain, France, Italy, Greece and Turkey during the course of a prospective study of hip fracture incidence and 1132 age-stratified controls selected from the neighborhood or population registers. The questionnaire examined aspects of work, physical activity past and present, diseases and drugs, height, weight, indices of co-morbidity and consumption of tobacco, alcohol, calcium, coffee and tea. Significant risk factors identified by univariate analysis included low body mass index (BMI), low sunlight exposure, a low degree of recreational physical activity, low consumption of milk and cheese, and a poor mental score. Co-morbidity including sleep disturbances, loss of weight, impaired mental status and poor appetite were also significant risk factors. Previous stroke with hemiplegia, prior fragility fractures, senile dementia, alcoholism and gastrectomy were associated with significant risk, whereas osteoarthrosis, nephrolithiasis and myocardial infarction were associated with lower risks. Taking medications was not associated with a difference in risk apart from a protective effect with the use of analgesics independent of co-existing osteoarthrosis and an increased risk with the use of anti-epileptic agents. Of the potentially 'reversible' risk factors, BMI, leisure exercise, exposure to sunlight and consumption of tea and alcohol and tobacco remained independent risk factors after multivariate analysis, accounting for 54% of hip fractures. Excluding BMI, 46% of fractures could be explained on the basis of the risk factors sought. Of the remaining factors low exposure to sunlight and decreased physical activity accounted for the highest attributable risks (14% and 9% respectively). The use of risk factors to predict hip fractures had relatively low sensitivity and specificity (59.6% and 61

  20. Risk factors for gastroenteritis: a nested case-control study.

    Science.gov (United States)

    Rodrigo, S; Sinclair, M; Wolfe, R; Leder, K

    2011-04-01

    This nested case-control study investigated the risk factors for gastroenteritis in a cohort using rainwater as their primary domestic water source. Consumption of beef [odds ratio (OR) 2·74, 95% confidence interval (CI) 1·56-4·80], handling of raw fresh chicken in the household (OR 1·52, 95% CI 1·02-2·29) and animal contact (OR 1·83, 95% CI 1·20-2·83) were found to be significant risk factors (P>0·05). Significant protective effects were observed with raw salad prepared at home (OR 0·33, 95% CI 0·18-0·58), consumption of salami (OR 0·60, 95% CI 0·36-0·98), and shellfish (OR 0·31, 95% CI 0·14-0·67). This study provides novel insight into community-based endemic gastroenteritis showing that consumption of beef was associated with increased odds of illness and with a population attributable fraction (PAF) of 57·6%. Detecting such a high PAF for beef in a non-outbreak setting was unexpected.

  1. A Study of Chinese Commercial Banks’ Credit Risk Assessment

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    Xiaosong Zheng

    2016-01-01

    Full Text Available It has been a long time that Chinese small and medium-sized enterprises (SMEs have difficulties in dealing with financial problems. As a result of the imperfect financial environment in China, SMEs cannot find the effective way to obtain the funding, especially from Chinese commercial banks. In practice, the existing credit risk assessment and management policies cannot adapt to the requirements of SMEs, which means that developing new mechanisms and management policies is necessary. Based on the previous studies and the economic realities, this paper analyzes the credit status of commercial banks and sorts out the complex background to make a valuable conclusion. In the section of credit risk assessment mechanisms for SMEs, the author compares three classical models and introduces a parameter selection method which measures the financial and non-financial factors together. Besides the theoretical section, a case of Agricultural Bank of China will be studied and the paper will focus on the credit rating system and explore the innovative service for SMEs.

  2. Studies on nursing risks and measures of clinical medication.

    Science.gov (United States)

    Li, Min; Bai, Jie; Huang, Jie

    2015-09-01

    To investigate the cause analysis of clinical medication nursing risks and propose relevant nursing measures, so as to control and reduce the clinical nursing risks and reach the physical and mental safety of patients and nurses. Clinical nursing risk events with 30 cases in TCM Hospital of Zhengzhou City from June 2010 to April 2012 were underwent statistical analyses. The risk of medication error ranked the first in the direct reasons of nursing risks, accounting for a higher ratio. Moreover, the reasons of nursing risks were also involved in nonstandard operation, disease observation and other relative factors. Nurses must fully understand the relative factors of medication nursing risks, regarding the patients as their own family and always permeating the consciousness of nursing risks into the working process.

  3. Flood risk changes over centuries in Rome: an empirical study

    Science.gov (United States)

    Di Baldassarre, Giuliano; Saccà, Smeralda; Tito Aronica, Giuseppe; Grimaldi, Salvatore; Crisci, Massimiliano

    2015-04-01

    Over centuries, the development of the historical city of Rome -close to one of the largest Italian rivers, the Tiber- has been intertwined with the magnitude and frequency of flooding events. The ancient Rome mostly developed on the (seven) hills, while the Tiber's floodplain was mainly exploited for agricultural purposes. A few small communities did settle in the riparian areas of the Tiber, but they had a relatively peaceful relationships with the frequent occurrence of flooding events. Nowadays, numerous people live in modern districts in the Tiber's floodplain, unaware of their exposure to potentially catastrophic flooding. The main goal of this research is to explore the dynamics of changing flood risk over the centuries between these two extreme pictures of the ancient and contemporary Rome. To this end, we carried out a socio-hydrological study by exploiting long time series of physical (flooding, river morphology) and social (urbanization, population dynamics) processes together with information about human interactions with the environment (flood defense structures). This empirical analysis showed how human and physical systems have been co-evolving over time, while being abruptly altered by the occurrence of extreme events. For instance, a large flooding event occurred in 1870 and contributed to the constructions of levees, which in turn facilitated the development of new urban areas in the Tiber's floodplain, while changed the societal memory of floods as well as the communities' perception of risk. This research work was also used to test the hypotheses of recent-developed models conceptualizing the interplay between floods and societies and simulating the long-term behavior of coupled human-water systems. The outcomes of this test provided interesting insights about the dynamics of flood risk, which are expected to support a better anticipation of future changes.

  4. Study of Hip Fracture Risk using Tree Structured Survival Analysis

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    Lu Y

    2003-01-01

    Full Text Available In dieser Studie wird das Hüftfraktur-Risiko bei postmenopausalen Frauen untersucht, indem die Frauen in verschiedene Subgruppen hinsichtlich dieses Risikos klassifiziert werden. Frauen in einer gemeinsamen Subgruppe haben ein ähnliches Risiko, hingegen in verschiedenen Subgruppen ein unterschiedliches Hüftfraktur-Risiko. Die Subgruppen wurden mittels der Tree Structured Survival Analysis (TSSA aus den Daten von 7.665 Frauen der SOF (Study of Osteoporosis Fracture ermittelt. Bei allen Studienteilnehmerinnen wurde die Knochenmineraldichte (BMD von Unterarm, Oberschenkelhals, Hüfte und Wirbelsäule gemessen. Die Zeit von der BMD-Messung bis zur Hüftfraktur wurde als Endpunkt notiert. Eine Stichprobe von 75% der Teilnehmerinnen wurde verwendet, um die prognostischen Subgruppen zu bilden (Trainings-Datensatz, während die anderen 25% als Bestätigung der Ergebnisse diente (Validierungs-Datensatz. Aufgrund des Trainings-Datensatzes konnten mittels TSSA 4 Subgruppen identifiziert werden, deren Hüftfraktur-Risiko bei einem Follow-up von im Mittel 6,5 Jahren bei 19%, 9%, 4% und 1% lag. Die Einteilung in die Subgruppen erfolgte aufgrund der Bewertung der BMD des Ward'schen Dreiecks sowie des Oberschenkelhalses und nach dem Alter. Diese Ergebnisse konnten mittels des Validierungs-Datensatzes reproduziert werden, was die Sinnhaftigkeit der Klassifizierungregeln in einem klinischen Setting bestätigte. Mittels TSSA war eine sinnvolle, aussagekräftige und reproduzierbare Identifikation von prognostischen Subgruppen, die auf dem Alter und den BMD-Werten beruhen, möglich. In this paper we studied the risk of hip fracture for post-menopausal women by classifying women into different subgroups based on their risk of hip fracture. The subgroups were generated such that all the women in a particular subgroup had relatively similar risk while women belonging to two different subgroups had rather different risks of hip fracture. We used the Tree Structured

  5. Risk Management from Corporate and FM Perspectives: Two case studies

    DEFF Research Database (Denmark)

    2012-01-01

    Purpose: To investigate how Risk Management (RM) is perceived and practiced in Facilities Management (FM) and corporate management and to evaluate the potential benefits of an increased application. Theory: RM is a generic management discipline, but apparently it has not achieved the attention...... it deserves in FM. Application of RM in FM could help to increase the strategic importance and awareness of FM among corporate managers. Approach: A preliminary study with expert interviews was initially conducted followed by a main study with an interview survey in two Danish case companies - a real estate...... company and a consulting engineering company. Findings: The research showed that RM was applied in both companies to a higher degree than initially expected, but often using other terminology. The real estate company had a much stronger focus on RM in relation to the technical aspects of real estate...

  6. Study on risk analysis of supply chain enterprises

    Institute of Scientific and Technical Information of China (English)

    Wu Xiaohui; Zhong Xiaobing; Song Shiji; Wu Cheng

    2006-01-01

    The sources of supply chain enterprise risk from different aspects including material flow, information flow, cash flow and partner relationship is analyzed. Measures for risk reduction have also been summarized from the aspects of risk sharing, information sharing, change of inventory control mode, and supply chain flexibility. Finally, problems in current research on supply chain risk management are pointed out and a discussion on future research trend is presented.

  7. THE IMPACT OF SEVERITY OF DIABETIC RETINOPATHY IN CARDIOVASCULAR DISEASE RISK ASSESSMENT USING FRAMINGHAM RISK SCORE - A PILOT STUDY

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    Nidhi

    2015-08-01

    Full Text Available Diabetic retinopathy (DR is the most common micro vascular complications of diabetes, estimated to affect approximately 100 million people worldwide, while cardiovascular disease (CVD is the leading cause of death in individuals with type II diabetes. There is limited Indian data reporting the association of Diabetic retinopathy and its severity with CVD. AIM : To study the relation between the severity of DR and risk of CVD in cen tral Indian subjects. MATERIALS AND METHODS : The subjects consisted of 50 patients with Diabetes mellitus type II having varying grades of diabetic retinopathy attending eye OPD of a tertiary care hospital in central India. 10 year risk of developing CVD was estimated using the Framingham Risk Score. RESULTS : The number of subjects with an increased risk of developing CVD increased with advancing age (28.57% in 40 - 49 years to 61 .53% in > 60 years age group. The risk of CVD was slightly more in males (55. 55% compared to females (43.47%. Out of the 30 patients having sight threatening diabetic retinopathy, 13 had low risk of developing CVD while 17 had high risk of developing CVD. The prevalence of sight threatening retinopathy was more in the high risk group (56.67% when compared to the low - risk group (40%. DISCUSSION : We found that more subjects having high risk of developing CVD had sight - threatening DR compared to those having low risk. CONCLUSION : Diabetic retinopathy may contribute to CVD risk in Indian population too. A careful cardiovascular assessment and follow - up may be required in individuals with diabetic retinopathy, using a larger sample size

  8. Retinopathy of prematurity: A study of prevalence and risk factors

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    Abdel H. A. A. Hakeem

    2012-01-01

    Full Text Available Background: Retinopathy of prematurity (ROP is a serious complication of prematurity treatment and can lead to blindness unless recognized and treated early. Objective: The objective was to estimate the prevalence of ROP in preterm infants in the Neonatal Intensive Care Unit (NICU, to identify the risk factors which predispose to ROP, and to assess the outcome of these cases. Materials and Methods: A ROP prospective screening survey was performed enrolling all prematures admitted to the NICU from January 2009 to December 2010, with a gestational age of 32 weeks or less at birth and a birth weight of 1500 g or less. Infants whose gestational age was >32 weeks or birth weight was >1500 g were included if they were exposed to oxygen therapy for more than 7 days. A total of 172 infants (84 males and 88 females had retinal evaluation by indirect ophthalmoscopy from the fourth postnatal week and followed up periodically. Perinatal risk factors for ROP were assessed using univariate and multivariate analysis. Infants who progressed to stage 3 ROP were given laser therapy. Results: Out of the studied 172 infants, 33 infants (19.2% developed ROP in one or both eyes; 18 (54.5% cases stage 1, 9 (27.3% cases stage 2, and 6 (18.2% cases stage 3. None of the studied neonates presented ROP at stages 4 or 5. The six cases diagnosed as ROP stage 3 underwent laser ablative therapy. Univariate analysis showed that there was a significant relationship between the occurrence of ROP and gestational age (P = 0.000, sepsis (P = 0.004, oxygen therapy (P = 0.018, and frequency of blood transfusions (P = 0.030. However, an insignificant relationship was found between the occurrence of ROP and sex, mode of delivery, birth weight, respiratory distress syndrome, patent ductus arteriosus, intraventricular hemorrhage, hypotension, phototherapy, duration of oxygen therapy, mechanical ventilation, and CPAP (all P > 0.05. Gestational age, sepsis, oxygen therapy, and frequency of

  9. Variáveis reprodutivas e risco para doenças benignas de mama: estudo caso-controle Reproductive variables and risk of benign breast diseases: a case-control study

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    Ellen E. Hardy

    1990-10-01

    Full Text Available Foram estudadas 257 mulheres com diagnóstico de doença benigna de mama (DBM, atestado por anatomopatológico ou citologia, e um controle para cada uma delas. Foram apresentados resultados das possíveis relações entre variáveis reprodutivas e o risco para DBM. Os casos e controles foram comparados levando em conta a idade na menarca e na menopausa, o número de gravidezes, de meses em que amamentaram e de ciclos menstruais ovulatórios, e os antecedentes familiares de câncer de mama. Mostraram influência significativa, em relação às DBM, a nuliparidade, aumentando o risco enquanto a idade de 30 ou mais anos no primeiro parto o reduziu; o número de ciclos ovulatórios, que foi significativamente maior para os casos, e a média de meses de uso de pílula, menor entre as mulheres com DBM. O uso de contraceptivos orais apresentou um efeito protetor apenas quando a duração total do uso foi maior que dois anos. Os resultados não se revelaram novos ou diferentes se comparados com outros estudos, mas confirmam a relativa concordância entre os fatores de risco para DBM e para câncer de mama, ainda que as relações entre esses fatores e as DBM não sejam tão claras como o são para o câncer, e existam também algumas discrepâncias.The purpose of the study was the identification of risk factors for benign breast diseases (BBD; 257 women with BBD diagnosed through pathological anatomy or citology and a matched control for each were studied. Subjects were selected at The State University of Campinas Hospital and at a private clinic. To enter the study cases had to have a first diagnosis of BBD between October 1979 and August 1984. The following BBD were considered: dysplasia, fibroadenoma, cystic disease, papilloma and ductal ectasia. Reproductive variables were studied as risk factors, including menstrual ovulatory cycles. The date on which the BBD was diagnosed was defined as the index date. For controls, data were considered up to when

  10. Risk perception and the economic crisis: a longitudinal study of the trajectory of perceived risk.

    Science.gov (United States)

    Burns, William J; Peters, Ellen; Slovic, Paul

    2012-04-01

    We conducted a longitudinal survey of public response to the economic crisis to understand the trajectory of risk perception amidst an ongoing crisis. A nation-wide panel responded to seven surveys beginning in late September 2008 at the peak of the crisis and concluded in October 2009. At least 600 respondents participated in each survey, with 413 completing all seven surveys. Our online survey focused on perceptions of risk (savings, investments, retirement, job), negative emotions toward the financial crisis (sadness, anxiety, fear, anger, worry, stress), confidence in national leaders to manage the crisis (President Obama, Congress, Treasury Secretary, business leaders), and belief in one's ability to realize personal objectives despite the crisis. We employed latent growth curve modeling to analyze change in risk perception throughout the crisis. Our results suggest that, in general, people's perceptions of risk appear to decrease most rapidly during the initial phase of a crisis and then begin to level off. Negative emotion about the crisis was the most predictive of increased risk perception, supporting the notion of risk as feelings. Belief in one's ability to realize personal objectives was also predictive. Confidence in national leaders, however, was not predictive of perceived risk. Finally, our results demonstrate that groups may experience a crisis differently depending on a combination of personal characteristics such as gender, income, numeracy, and political attitude. Risk management and communication should work in sync with these mechanisms and differences across groups.

  11. Risk factors for episiotomy: a case-control study

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    Giordana Campos Braga

    2014-10-01

    Full Text Available Objective: obtaining information on the factors associated with episiotomy will be useful in sensitizing professionals to the need to minimize its incidence. Therefore, the objective of this study was to evaluate risk factors for episiotomy in pregnant women who had undergone vaginal delivery at a university maternity hospital in northeastern Brazil. Methods: a case-control study was conducted with pregnant women submitted to episiotomy (cases and pregnant women not submitted to episiotomy (controls between March 2009 and July 2010 at the Professor Fernando Figueira Integral Medicine Institute (IMIP in Recife, Brazil, in a ratio of 1 case to 2 controls. The study variables consisted of: whether episiotomy was performed, demographic, obstetric and fetal characteristics (primiparity, analgesia, instrumental delivery, fetal distress, etc., external factors (day and time of delivery, professional attending delivery and factors directly related to delivery. Odds ratios (OR and 95% confidence intervals (95%CI were calculated. Multivariate analysis was performed to determine the adjusted risk of episiotomy. Results: a total of 522 women (173 cases and 349 controls were included. It was found that deliveries with episiotomy were more likely to have been attended by staff physicians (OR = 1.88; 95%CI: 1.01 - 3.48, to have required forceps (OR = 12.31; 95%CI: 4.9 - 30.1 and to have occurred in primiparas (OR = 4.24; 95%CI: 2.61 - 6.89. The likelihood of a nurse having attended the delivery with episiotomy was significantly lower (OR = 0.29; 95%CI: 0.16 - 0.55. Conclusion: episiotomy was found to be strongly associated with deliveries attended by staff physicians, with primiparity, and with instrumental delivery, and was less common in deliveries attended by nurses.

  12. Ciclos económicos y retórica administrativa. Dualidad ideológica en Colombia Ciclos económicos y retórica administrativa. Dualidad ideológica en Colombia

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    César Alexander Toro Suárez

    2007-06-01

    Full Text Available En 1992, Stephen R. Barley y Gideon Kunda, profesores de la universidad deStanford y de la universidad de Tel Aviv respectivamente, publicaron un estudiotitulado: “Desing and devotion: surges of rational and normative ideologies ofcontrol in managerial discourse”* en el que encontraron que en Estados Unidos,las teorías administrativas se presentan en oleadas de retórica en correspondenciadirecta con los ciclos económicos. De esta manera, las teorías de contenido racional(dirigidas al control del trabajo sobresalen en períodos de crecimiento, y las decontenido normativo (dirigidas al control del trabajador prevalecen en contraccióneconómica. Partiendo de estos resultados, y retomando la esquematizaciónhistórica del surgimiento de las oleadas de ideología administrativa en Colombiaplanteada por el profesor Francisco López G. (1998, aquí se realizó un estudiosimilar y se encontró que el desarrollo del pensamiento administrativo en Colombiatiene igualmente relación con el ciclo económico, emerge en oleadas y presentacaracterísticas particulares.Professors Stephen R. Barley and Gideon Kunda (1992 conducted a study titled: “Design and Devotion: Surges of Rational and Normative Ideologies of Control in Managerial Discourse” in which they found that in the United States management theories are presented in waves of rhetoric which corresponded directly with economic cycles. In this way, theories with rational content (those directed at controlling work stand out in periods of growth, while those with normative content (those directed at controlling the worker prevail in times of economic shrinking. Based on these results, and returning to the historical scheme of the appearance of waves of management ideology in Colombia proposed by professor Francisco López G. (1998, a similar study was conducted in which the development of management thinking in Colombia was found to also have a relation to the economic cycle, to

  13. COMPARATIVE STUDY BETWEEN TRADITIONAL AND ENTERPRISE RISK MANAGEMENT -A THEORETICAL APPROACH

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    Cican Simona-Iulia

    2014-07-01

    Full Text Available The complexity, volatility and unpredictability of the current economic environment are a daily reminder that organizations face many risks. The traditional approach, according to which risk is a necessary evil which must be removed, is no longer sufficient and that is why companies nowadays are forced to spend significant resources to manage risks. Risk transparency is what one looks for; therefore, identification and management of risks within an organization become increasingly necessary for success and longevity. Risk approach has a major role in a company’s ability to avoid, reduce and turn risks into opportunities. Enterprise risk management is a new concept that revolutionizes the traditional approach and summarizes risk management in an integrated, comprehensive and strategic system. Studies use several synonyms for enterprise risk management such as integrated risk management, holistic risk management, global risk management and strategic risk management. Enterprise risk management implements at the end of the last century a new way to deal with risks: the holistic approach. This risks approach – i.e. interaction of several types of risks which become increasingly threatening and varied and may cause more damage than individual risk – brings forward the need of risk management and raises issues at the highest level of company management. For a proper view on company risks, each individual risk and the possibility of risk interaction must be understood. This is essential to establish a risk classification according to their impact on the company. Traditional approach on risk management, as a management function, is limited to only threats and losses, so relatively few organizations see risks as potential earning-generated opportunities. However, risk management process is not radically changed. Enterprise risk management is an improved version of the traditional risk management, created by expanding its scope. The new risk

  14. Towards a Typology of At-Risk Students: A Case Study in Singapore

    Science.gov (United States)

    Dobele, Angela R.; Kopanidis, Foula; Gangemi, Michael; Thomas, Stuart; Janssen, Rabea; Blasche, Rose E.

    2012-01-01

    The purpose of this study is to examine at-risk students and the reasons they give to explain their poor academic performance, with a view to developing a typology of at-risk students. A case study methodology was used to investigate the total population of at-risk students for Semester 2, 2008 studying at the Singapore campus of an…

  15. A competing-risk-based score for predicting twenty-year risk of incident diabetes: the Beijing Longitudinal Study of Ageing study

    Science.gov (United States)

    Liu, Xiangtong; Chen, Zhenghong; Fine, Jason Peter; Liu, Long; Wang, Anxin; Guo, Jin; Tao, Lixin; Mahara, Gehendra; Yang, Kun; Zhang, Jie; Tian, Sijia; Li, Haibin; Liu, Kuo; Luo, Yanxia; Zhang, Feng; Tang, Zhe; Guo, Xiuhua

    2016-01-01

    Few risk tools have been proposed to quantify the long-term risk of diabetes among middle-aged and elderly individuals in China. The present study aimed to develop a risk tool to estimate the 20-year risk of developing diabetes while incorporating competing risks. A three-stage stratification random-clustering sampling procedure was conducted to ensure the representativeness of the Beijing elderly. We prospectively followed 1857 community residents aged 55 years and above who were free of diabetes at baseline examination. Sub-distribution hazards models were used to adjust for the competing risks of non-diabetes death. The cumulative incidence function of twenty-year diabetes event rates was 11.60% after adjusting for the competing risks of non-diabetes death. Age, body mass index, fasting plasma glucose, health status, and physical activity were selected to form the score. The area under the ROC curve (AUC) was 0.76 (95% Confidence Interval: 0.72–0.80), and the optimism-corrected AUC was 0.78 (95% Confidence Interval: 0.69–0.87) after internal validation by bootstrapping. The calibration plot showed that the actual diabetes risk was similar to the predicted risk. The cut-off value of the risk score was 19 points, marking mark the difference between low-risk and high-risk patients, which exhibited a sensitivity of 0.74 and specificity of 0.65. PMID:27849048

  16. Risk of recurrent venous thrombosis related to past provoking risk situations: follow-up of a cohort study.

    Science.gov (United States)

    Ribeiro, Daniel D; Lijfering, Willem M; Barreto, Sandhi M; Lopes, Fabiane Dias; Pires, Giselli de Souza; Rosendaal, Frits R; Rezende, Suely M

    2013-07-01

    Strategies targeting at classifying the risk for recurrent venous thrombosis are needed. We previously hypothesized, by studying a cohort of patients, that those who had 'survived' risk situations for venous thrombosis without developing it would, after a first venous thrombosis, have a low recurrence risk. Therefore, we re-evaluated the same cohort, now with a longer follow-up. Patients, after a first confirmed venous thrombosis event, were followed for an average of 43 months after suspension of anticoagulation. Patients with indication for indefinite anticoagulation were not included. The primary endpoint was objective recurrent venous thrombosis. Recurrent venous thrombosis was recorded in 9% of 378 eligible patients. Patients with a provoked first event and positive past risk situations for venous thrombosis had an incidence rate of recurrence of 1.26 (95% CI, 0.60-2.31) per 100 patient-years. The incidence rate ratio (IRR) of this subgroup compared with patients with a provoked event without other past risk situations for venous thrombosis was 0.8 (95% CI 0.2-2.9). This IRR was 2.8 (95% CI, 1.2-6.5) in patients with an unprovoked event and positive past risk situations and 7.1 (95% CI, 3.0-17.1) in patients with an unprovoked event and no past risk situations. When only idiopathic first events were evaluated the IRR was 2.5 (95% CI, 1.1-5.9) for patients without past risk situation compared with those with these history. In this study, asking a patient about past exposure to risk factors for venous thrombosis long before the occurrence of a first venous thrombosis occurred, could be used to classify patients with a first unprovoked venous thrombosis at higher risk for recurrence of venous thrombosis.

  17. Assessing Landscape Ecological Risk in a Mining City: A Case Study in Liaoyuan City, China

    OpenAIRE

    2015-01-01

    Landscape ecological risk assessment can effectively identify key elements for landscape sustainability, which directly improves human wellbeing. However, previous research has tended to apply risk probability, measured by overlaying landscape metrics to evaluate risk, generally lacking a quantitative assessment of loss and uncertainty of risk. This study, taking Liaoyuan City as a case area, explores landscape ecological risk assessment associated with mining cities, based on probability of ...

  18. Plantar pitted keratolysis: a study from non-risk groups

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    Asli Feride Kaptanoglu

    2012-02-01

    Full Text Available Pitted keratolysis is an acquired, superficial bacterial infection of the skin which is characterized by typical malodor and pits in the hyperkeratotic areas of the soles. It is more common in barefooted people in tropical areas, or those who have to wear occlusive shoes, such as soldiers, sailors and athletes. In this study, we evaluated 41 patients who had been diagnosed with plantar pitted keratolysis. The patients were of high socioeconomic status, were office-workers, and most had a university degree. Malodor and plantar hyperhydrosis were the most frequently reported symptoms. The weight-bearing metatarsal parts of the feet were those most affected. Almost half the women in the study gave a history of regular pedicure and foot care in a spa salon. Mean treatment duration was 19 days. All patients were informed about the etiology of the disease, predisposing factors and preventive methods. Recurrences were observed in only 17% of patients during the one year follow-up period. This study emphasizes that even malodorous feet among non-risk city dwellers may be a sign of plantar pitted keratolysis. A study of the real incidence of the disease in a large population-based series is needed.

  19. Meta-analysis of studies using statins as a reducer for primary liver cancer risk

    Science.gov (United States)

    Zhong, Guo-Chao; Liu, Yan; Ye, Yuan-Yuan; Hao, Fa-Bao; Wang, Kang; Gong, Jian-Ping

    2016-01-01

    A protective effect of statins on primary liver cancer (PLC) risk has been suggested. However, issues about the dose–response relationship, the protective effect of individual statins, and PLC risk reduction among at-risk populations remain unsolved. Therefore, a meta-analysis was conducted. PubMed and EMBASE were searched for studies providing the risk ratio (RR) on statins and PLC risk. Summary RRs were calculated using a random-effects model. Twenty-five studies were identified. Stain use was significantly associated with a reduced risk of PLC (RR = 0.60, 95% confidence interval (CI) = 0.53–0.69). The summary RR for every additional 50 cumulative defined daily doses per year was 0.87 (95% CI = 0.83–0.91). Evidence of a non-linear dose–response relationship between statins and PLC risk was found (Pnon-linearity < 0.01). All individual statins significantly reduced PLC risk, and the risk reduction was more evident with rosuvastatin. The inverse association between statins and PLC risk remained among populations with common risk factors. Subgroup analyses revealed more significant reduction in PLC risk by statins in high- versus non-high-risk populations (Pinteraction = 0.02). Overall, these findings add to our understanding of the association between statins and PLC risk. Whether statin use is causally associated with a reduced risk of PLC should be further studied. PMID:27198922

  20. Risk assessment study on bridge foundation in deep overlying stratum

    Institute of Scientific and Technical Information of China (English)

    Zhang Xiangqun; Wang Jingguo; Liu Manhong

    2012-01-01

    Based on the analysis about the hydrogeological conditions and engineering geological conditions, this paper makes analysis on the possible risks of the deep overlying stratum foundation and establishes the risk evaluation index system during the foundation operating period. Such methods as analytic hierarchy process (AHP) , Delphi method and fuzzy comprehensive evaluation method are adopted to make the quantitative analysis on the risk factors and establish the risk judgment model. According to the actual engineering of Taizhou Bridge, the paper evaluates the risk of the foundation during the operating period at the condition of deep overlying stratum. The evaluation results can provide the reference for the risk management of the bridge foundation durin~ the ooerating period.

  1. Revisitando a teoria do ciclo do produto Revisiting the product cycle theory

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    Eneuton Pessoa

    2007-08-01

    Full Text Available Este artigo busca refletir sobre uma questão-chave que perpassa grande parte da literatura crítica à teoria do ciclo do produto: o que foi superado e o que permanece vivo nessa teoria. Após sistematizar o mecanismo básico do ciclo do produto, discutem-se algumas principais insuficiências apontadas e/ou sugeridas pela literatura. Argumenta-se que, se não mais se sustenta a hipótese de que a dinâmica das inovações e dos investimentos diretos externos responde à cronologia do ciclo de vida do produto, por outro lado, a hipótese de que as vantagens comparativas possuem um caráter dinâmico, cuja natureza e importância relativa se modificam ao longo do tempo, em resposta a mudanças nos condicionantes da produção, e conforme o estágio de desenvolvimento e complexidade do produto, permanece viva e mais atual do que nunca.This article aims to think about a key-question that involves the majority of the critic literature in respect to the product-cycle theory. What is over and what remains alive in this theory? After systematizing the basic mechanism of the product-cycle theory, it discusses some of its main insufficiencies, how it is appointed or suggested by the literature. Summarily, we argue that, if it is over the hypothesis which argues that the dynamics of innovations, and the foreign direct investments depends on the product life cycle chronology, on the other side, it remains alive and does up-to-date the hypothesis which argues that the comparative advantages have a dynamic character, which nature and relative account is modified along time in response to changes in the production conditions, in accordance to the product evolution and its complexity.

  2. Comunidades virtuales de profesionales, trayectorias y ciclos de vida: aportes a la discusión

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    Agustín Zanotti

    2015-05-01

    Full Text Available Los estudios sobre comunidades virtuales se han ampliado en las dos últimas décadas, de la mano del desarrollo de las Tecnologías de la Información y la Comunicación y su difusión sobre numerosos dominios. El presente artículo problematiza algunas de las categorías conceptuales utilizadas frecuentemente en este campo, a partir de los resultados obtenidos en dos casos de estudio sobre comunidades virtuales: profesionales de la comunicación y programadores de software libre. A lo largo del artículo, comenzamos por definir a las comunidades virtuales y algunas de sus tipologías posibles. Nos referimos específicamente a comunidades de profesionales o comunidades de práctica, relacionadas con especialistas de diferentes ámbitos, dedicadas a compartir recursos, experticia y conocimiento. Junto con ello, discutimos tres nociones de ciclo de vida asociada a estos espacios, centradas en las plataformas de interacción, los participantes y los objetivos grupales. Los casos considerados nos permiten reconocer ciclos de vida con similitudes y diferencias. Estas incluyen procesos de migración y reconversión. Junto a ello observamos mudanzas en los objetivos grupales, liderazgos y recambios generacionales. Las comunidades analizadas nos permitirán así problematizar, desde un abordaje socio-técnico, la noción de ciclo de vida con vistas a reconstruir la complejidad de las trayectorias posibles.

  3. ARQUITECTURA DE LA RED VIRTUAL DE APRENDIZAJE PARA EL CICLO BÁSICO (FACES-UC

    Directory of Open Access Journals (Sweden)

    Neyda Ibañez

    2011-11-01

    Full Text Available La sociedad del siglo XXI demanda una universidad adaptada a la nueva realidad que ofrece el desarrollo de la comunicación basada en la tecnología digital computarizada. En virtud de ello, la investigación tuvo como objetivo el diseñar la red virtual de aprendizaje para facilitadores y estudiantes del Ciclo Básico de la Facultad de Ciencias Económicas y Sociales de la Universidad de Carabobo (FaCES-UC, siendo este uno de los objetivos del proyecto LOCTI titulado Formación, capacitación y fortalecimiento a facilitadores del Ciclo Básico y de las Escuelas de FaCES-UC, en el manejo de entornos virtuales como herramientas de aprendizaje. Metodológicamente, el estudio se ubicó en el paradigma positivista de tipo descriptivo, con una población de 72 profesores, calculándose una muestra de 237 estudiantes, con muestreo aleatorio simple, utilizando la técnica de observación directa y aplicando como instrumento el cuestionario simple con 27 preguntas cerradas y dicotómicas. Los resultados arrojaron que más del 95 por ciento de los estudiantes y más del 37 por ciento de los profesores aportaron al diseño de la red virtual de aprendizaje. Se concluye la arquitectura del sitio Web a través de la clasificación de tres criterios que persiguen brindar a la comunidad tanto interna como externa a la Universidad de Carabobo, un portal que ofrezca y difunda información y servicios del Ciclo Básico de FaCES-UC y de sus diversas Cátedras que lo conforman.

  4. Potential risk factors for diabetic neuropathy: a case control study

    Directory of Open Access Journals (Sweden)

    Nooraei Mahdi

    2005-12-01

    Full Text Available Abstract Background Diabetes mellitus type II afflicts at least 2 million people in Iran. Neuropathy is one of the most common complications of diabetes and lowers the patient's quality of life. Since neuropathy often leads to ulceration and amputation, we have tried to elucidate the factors that can affect its progression. Methods In this case-control study, 110 diabetic patients were selected from the Shariati Hospital diabetes clinic. Michigan Neuropathic Diabetic Scoring (MNDS was used to differentiate cases from controls. The diagnosis of neuropathy was confirmed by nerve conduction studies (nerve conduction velocity and electromyography. The multiple factors compared between the two groups included consumption of angiotensin converting enzyme inhibitors (ACEI, blood pressure, serum lipid level, sex, smoking, method of diabetes control and its quality. Results Statistically significant relationships were found between neuropathy and age, gender, quality of diabetes control and duration of disease (P values in the order: 0.04, 0.04, Conclusion In this study, hyperglycemia was the only modifiable risk factor for diabetic neuropathy. Glycemic control reduces the incidence of neuropathy, slows its progression and improves the diabetic patient's quality of life. More attention must be paid to elderly male diabetic patients with poor diabetes control with regard to regular foot examinations and more practical education.

  5. [Health risks study in a pottery environment in Morocco].

    Science.gov (United States)

    Laraqui, C H; Caubet, A; Laraqui, O; Rahhali, A E; Curtes, J P; Verger, C

    2000-01-01

    Morocco is famous for its potteries, the largest of which are located at Rabat, Safi, Marrakech and Fes. This cross-sectional, descriptive epidemiological survey was carried out over an eight-month period, from January to August 1997. The study population consisted of 290 male workers from 36 workshops. The study involved a social and medical survey (a questionnaire and medical examination for all workers, with biological assessment for a representative sample of 95 craftsmen) and an analysis of the working conditions in which atmospheric pollution at the pottery was evaluated. Atmospheric concentrations of zinc, copper, iron, chrome and lead were determined. Only lead levels were found to be significantly high and were analyzed on three occasions. This study demonstrates poor working conditions and a lack of respect for the regulations concerning specific prevention measures and the health rules applicable to establishments where personnel are routinely exposed to the risk of lead poisoning. Various pathological conditions were observed, with the following prevalences: skeletal muscle 67.6%, dermatological 8.3%, digestive 58%, respiratory 28% and neurological 35.5%. Several nonspecific, often minor, clinical signs were recorded for most of the potters but the toxicological analysis confirmed lead contamination in 74% of the exposed subjects (plasma lead concentration, CPU, ALAU). The potteries of Morocco are not subject to any protection. Special technical and medical surveillance should be introduced and the laws concerning exposure to lead should be applied.

  6. Gabinetes presidenciais, ciclos eleitorais e disciplina legislativa no Brasil

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    Amorim Neto Octavio

    2000-01-01

    Full Text Available All presidential cabinets formed in Brazil between 1985 and 1998 included politicians from more than one party and could, in principle, be defined as coalition cabinets. The article evaluates to what extent this is a valid statement as far as the legislative behavior of the cabinet parties is concerned. An indicator is proposed for measuring the rate of cabinet coalescence, based on the ratio between the percentage of ministerial posts held by each party represented in the cabinet and the percentage of legislative seats held by each of these parties. Regression analysis is used to ascertain what impact the rate of cabinet coalescence has on the legislative discipline of cabinet parties. In addition to this coalescence index, the study also tests the effect of electoral cycles and the ideological range of cabinets on legislative discipline. Results indicate that the legislative discipline of cabinet parties is only consistent with what would be expected of coalition governments in parliamentary regimes when the cabinet displays a relatively high rate of coalescence. Findings also show that the party support to president tends to decrease over the course of the president's term and that the greater the ideological distance between the president and a given party, the lower the support rate this party will display for the head of government.

  7. Il cammino interiore nel ciclo Palimpsesty di Vasyl’ Stus

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    Alessandro Achilli

    2009-12-01

    Full Text Available Alessandro Achilli The Quest for the Self in Vasyl’ Stus’s Poetry The Author translates and discusses some poems from Vasyl’ Stus’s collection Palimpsesty. The work of this major Ukrainian poet, who died in a Soviet prison in 1985, is almost unknown in Italy, while his fame in other countries is linked mainly to his dissident activity, which has been the cause of his somewhat narrow reception as a fi ghter-poet. Stus’s literary achievements are rooted in the wide tradition of European poetry and thought. The Author presents those poems, in which the lyrical subject focuses on himself and on the exploration of his inner world, condensing it in spatial and geometrical forms. The peculiar imagery of this poetic world, which is reduced to a small number of obsessively recurring motifs, is also examined. The Author hopes to arouse curiosity and interest in this little studied chapter of the Ukrainian-Slavic-European poetic history of the Twentieth century.

  8. Diabetes Risk Factors, Diabetes Risk Algorithms, and the Prediction of Future Frailty: The Whitehall II Prospective Cohort Study

    Science.gov (United States)

    Bouillon, Kim; Kivimäki, Mika; Hamer, Mark; Shipley, Martin J.; Akbaraly, Tasnime N.; Tabak, Adam; Singh-Manoux, Archana; Batty, G. David

    2013-01-01

    Objective To examine whether established diabetes risk factors and diabetes risk algorithms are associated with future frailty. Design Prospective cohort study. Risk algorithms at baseline (1997–1999) were the Framingham Offspring, Cambridge, and Finnish diabetes risk scores. Setting Civil service departments in London, United Kingdom. Participants There were 2707 participants (72% men) aged 45 to 69 years at baseline assessment and free of diabetes. Measurements Risk factors (age, sex, family history of diabetes, body mass index, waist circumference, systolic and diastolic blood pressure, antihypertensive and corticosteroid treatments, history of high blood glucose, smoking status, physical activity, consumption of fruits and vegetables, fasting glucose, HDL-cholesterol, and triglycerides) were used to construct the risk algorithms. Frailty, assessed during a resurvey in 2007–2009, was denoted by the presence of 3 or more of the following indicators: self-reported exhaustion, low physical activity, slow walking speed, low grip strength, and weight loss; “prefrailty” was defined as having 2 or fewer of these indicators. Results After a mean follow-up of 10.5 years, 2.8% of the sample was classified as frail and 37.5% as prefrail. Increased age, being female, stopping smoking, low physical activity, and not having a daily consumption of fruits and vegetables were each associated with frailty or prefrailty. The Cambridge and Finnish diabetes risk scores were associated with frailty/prefrailty with odds ratios per 1 SD increase (disadvantage) in score of 1.18 (95% confidence interval: 1.09–1.27) and 1.27 (1.17–1.37), respectively. Conclusion Selected diabetes risk factors and risk scores are associated with subsequent frailty. Risk scores may have utility for frailty prediction in clinical practice. PMID:24103860

  9. Incidencia de los Movimientos Oculares en el proceso lector de alumnos de Primer ciclo de Primaria.

    OpenAIRE

    Alejo-Ramos, Cristina

    2013-01-01

    Los movimientos oculares en la lectura son importantes para el proceso de aprendizaje de los niños. Este trabajo de investigación tiene como objetivo, conocer la influencia de los movimientos oculares en la lectura. Para ello se llevó a cabo un estudio, con una muestra de 30 alumnos del Primer ciclo de Primaria, es decir, Primero y Segundo, del mismo centro educativo. Una vez que se realizaron las pruebas oportunas, se pudo comprobar cómo estaban relacionadas motricidad ocular y lectura...

  10. Los terrores nocturnos: implicaciones educativas en el 2º ciclo de Educación Infantil

    OpenAIRE

    Parra-Peñafiel, Clara

    2014-01-01

    El presente trabajo trata el tema de los terrores nocturnos desde el ámbito educativo. Para ello, se ha planteado conocer estrategias relacionadas con los terrores nocturnos infantiles en el 2º ciclo de Educación Infantil. La metodología utilizada ha sido el análisis teórico de estudios relacionados con los terrores nocturnos para conocer el estado de la cuestión. Como conclusiones más relevantes, el docente debería conocer las principales características de este trastorno del sueño para pode...

  11. EL CICLO ECONÓMICO EN COSTA RICA: 1980-1999

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    José Francisco Pacheco Jiménez

    2002-12-01

    Full Text Available Prácticamente todas las escuelas del pensamiento económico reconocen que las economías no se mueven de forma lineal sino que siguen un patrón cíclico recurrente que alterna periodos de altos con bajos niveles de actividad. El análisis de la naturaleza, causas y consecuencias de tales expansiones y contracciones es el principal objetivo de la Teoría de los Ciclos de Negocios (CN.A pesar que la comprensión de la naturaleza, causas y dinámica de un ciclo es vital tanto para los formuladores de política como para el sector privado, son pocos los intentos por brindar una interpretación económica de tales fluctuaciones en países pequeños y abiertos como Costa Rica. Así, queda aun una importante brecha teórica y empírica que explique las regularidades cíclicas presenten a estas naciones.El presente artículo es un intento en ese sentido. El trabajo busca evaluar si el patrón observado en la economía costarricense pertenece a un CN, y si así fuese, explorar en la causa y origen de los impulsos que dan lugar a esos movimientos. Con ello se amplía y complementa algunas investigaciones hechas anteriormente por autores como Azofeifa y otros (1995 y Gaba y otros (1993, de corte más estadístico.La principal conclusión del artículo es que, efectivamente, el patrón cíclico de Costa Rica puede ser considerado como un CN cuya causa se encuentra en las variaciones de la inversión. Los cambios experimentados en ella están alta, pero no exclusivamente, condicionados por el ciclo de los Estados Unidos, el cual canaliza sus fluctuaciones por medio de cambios en exportaciones y tasas de interés. Para tal efecto, el trabajo La investigación se apoya en un modelo kaleckiano/keynesiano que describe la secuencia impulso, causa y ciclo. Empíricamente, se utilizan herramientas econométricas varias tales como Modelos ARIMA y Vectores Autorregresivos para extraer el componente cíclico y probar la relación entre EEUU y Costa Rica.

  12. Los ciclos económicos departamentales en Colombia, 1960-2011

    OpenAIRE

    Vásquez Bedoya, Fredy; Restrepo Ochoa, Sergio Iván; Lopera Castaño, Mauricio; Restrepo Estrada, María Isabel

    2014-01-01

    En este trabajo se estima el ciclo del PIB nacional y de algunos departamentos entre 1960 y 2011 usando el modelo de tendencia lineal local de Nelson y Plosser, así como el coeficiente de correlación entre el componente cíclico de las series del PIB departamental y nacional para clasificar sus co-movimientos. El estudio revela una diversidad de comportamientos de las fluctuaciones económicas departamentales con respecto a la nacional y, además, que las economías departamentales fuertemente pr...

  13. Creciendo emocionalmente. Desarrollo de las competencias socioemocionales en el 1r Ciclo de Primaria

    OpenAIRE

    Olmedo-Fernández, Eva

    2013-01-01

    Este trabajo propone una propuesta de intervención para mejorar las competencias socioemocionales de los alumnos de Primer Ciclo de Educación Primaria. Su objetivo es aportar una visión general de los beneficios de la educación emocional en el desarrollo de la personalidad del alumnado. Se inicia con un breve repaso de aspectos teóricos clave en esta materia, definiendo conceptos tales como emoción, inteligencia emocional, educación emocional y habilidades sociales. A continuación, se inci...

  14. UN CICLO CERRADO: EL PATRIMONIO NOBILIARIO CONSTRUIDO EN LA CIUDAD DE MURCIA

    Directory of Open Access Journals (Sweden)

    Francisco Calvo García-Tornel

    2011-01-01

    Full Text Available La presencia en el tejido urbano de la ciudad de Murcia de las viviendas o palacios de la nobleza, está directamente relacionado con la evolución patrimonial de este grupo social. Cerrado el ciclo en el que el poder social nobiliario fue decisivo en la vida regional, su memoria se conserva básicamente a través de sus casas-palacio, un patrimonio histórico y, en buena medida, también artístico que ha sufrido una suerte muy desigual hasta el presente.

  15. El estudio de las rocas y minerales en el ciclo medio de la EGB

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    Juan GONZÁLEZ CRESPO

    2009-11-01

    Full Text Available El estudio de las rocas y minerales ha sido generalmente escaso en estos niveles de EGB. La mayoría de las veces se limita a conceptos teóricos elementales y en no pocas ocasiones a contenidos ajenos a la experiencia del alumnado. Quizá esto se deba a la indudable complejidad en algunos aspectos de estas materias, dificultad terminológica que presenta en no pocas ocasiones, escasez de recursos en los centros ... Todo lo cual ha llevado a que estas materias se consideren más propias de niveles superiores y, por tanto, algo ajeno para los alumnos de este ciclo.

  16. Estructura del hogar y ahorro durante el ciclo de vida: Evidencia de las cohortes peruanas

    OpenAIRE

    Valdivia, Martín; Saavedra, Jaime

    2003-01-01

    Los cambios demográficos que ocurren en el Perú y en el resto de países en desarrollo tienen implicancias potenciales sobre un conjunto de sectores, en particular sobre el sistema de seguridad social para la vejez. La naturaleza de los efectos, sin embargo, depende del comportamiento de los individuos, y sus hogares, a lo largo del ciclo de vida; por ejemplo, en lo concerniente a sus decisiones laborales (momento de retiro) y de ahorro, las que a su vez están relacionadas con los arreglos int...

  17. Alimentación y actividad física en el ciclo superior de primaria

    OpenAIRE

    Garrido, Alfred

    2012-01-01

    El presente Trabajo Final de Grado pretende explorar los hábitos de salud de los niños y niñas del ciclo superior de primaria de la escuela Madres Concepcionistas de Barcelona. Para ello se ha elaborado un cuestionario propio, destinado a conocer las conductas y hábitos de alimentación, actividad física y estilo de vida. A partir de las conclusiones del estudio realizado, se ha diseñado un plan de intervención útil para corregir los hábitos poco saludables y afianzar las conductas saludabl...

  18. Ciclos Económicos y accidentes laborales en España

    OpenAIRE

    Ayon Auhing, Hector Eduardo

    2016-01-01

    El presente estudio analiza la influencia que tienen los ciclos económicos sobre la accidentabilidad laboral, y la comprobación de la vigencia en conjunto, de los enfoques teóricos dominantes,que buscan explicar esta relación mediante la perspectiva de la intensificación (Kossoris, 1940) y la vulnerabilidad de los trabajadores (Nichols, 1986).Además este trabajo se apoya en la investigación de los estudios de otros autores sobre temática similar es y su...

  19. Repertorios y ciclos de movilización juvenil en Chile (2000-2012

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    Oscar Aguilera Ruiz

    2012-01-01

    Full Text Available Los procesos de movilización y protesta social realizados por los movimientos juveniles y estudiantiles en Chile en la actualidad deben ser entendidos en el marco de un cambio en los repertorios de movilización así como en el contexto de un ciclo de movilización más amplio. De allí que la caracterización sincrónica debe ser complementada con una mirada diacrónica de las prácticas movilizadoras de los jóvenes

  20. Projecto Rodentia : etologia aplicada na sala de aula do 1º Ciclo

    OpenAIRE

    2008-01-01

    p. 275-279 O Projecto Rodentia, implementado no ano 2006/2007, visa promover a cultura científica em alunos do 1º ciclo do Ensino Básico, familiarizando-os com o Método Científico e desenvolvendo competências conceptuais, processuais e atitudinais, com base na Etologia Aplicada e na reflexão ética sobre o bem-estar animal. Foram instalados em três salas de aula habitats especialmente desenhados, contendo cada um dois ratos de laboratório. Inicialmente orien...

  1. El ciclo evolutivo experimental de Diphyllobothrium erinaceieuropei en Paracyclops fimbriatus, larvas de Bufo arenarum y caninos

    OpenAIRE

    Venturini,Lucila

    1989-01-01

    El objetivo del trabajo fue lograr la reproducción experimental del ciclo evolutivo de Diphyllobothrium erinaceieuropei Rudolphi 1819 (Cestoda, Pseudophyllidea) con la intervención de Paracyclops fimbriatus y larvas de Bufo arenarum como hospedadores intermediarios y caninos como hospedadores definitivos. Los huevos del parásito se obtuvieron de heces de caninos infectados naturalmente y se conservaron refrigerados en agua. Se incubaron 7 días a 25°C para que desarrollaran los coracidios y se...

  2. Calidad total en un modelo integrado de proceso software y ciclo de vida

    OpenAIRE

    2009-01-01

    La modelización del Proceso Software constituye un marco de referencia para la organización de las actividades que involucran todas las etapas del desarrollo. La representación del ciclo de vida define los estados por los que pasa un producto software y la representación del proceso software define el conjunto de actividades esenciales no ordenadas en el tiempo que requiere el desarrollo de software. En el presente artículo se exponen los avances de una investigación que propone una modeli...

  3. Síndrome de Angelman:inclusão no ensino regular (1º ciclo)

    OpenAIRE

    Matos, Maria Alice Basto Alves de

    2013-01-01

    A inclusão de alunos com necessidades educativas especiais em escolas do ensino regular tem revelado ser um grande desafio. A escola deve constituir uma gestão inclusiva adequada às suas diversas necessidades. Este estudo tem como objetivo percecionar se os alunos portadores com síndrome de Angelman estão incluídos nas turmas do ensino regular do 1º ciclo e analisar como os profissionais de educação e respetivos pais enfrentam a sua inclusão. Para tal, produzimos um inquérito destinado ...

  4. La teoría del consumo y de los ciclos en Thorstein Veblen

    Directory of Open Access Journals (Sweden)

    Hernán Alejandro Morero

    2013-06-01

    Full Text Available Thorstein Veblen (1857-1929 fue uno de los fundadores de la economía institucional norteamericana. Este artículo presenta su teoría del consumo basada en los hábitos expuesta en la Teoría de la clase ociosa, y su teoría de los ciclos económicos y las crisis expuesta en la Teoría de la empresa de negocios. Para situarlas en contexto se esboza una síntesis de su pensamiento y de sus críticas a la economía ortodoxa.

  5. El ciclo de las rocas. Alteración biológica a nivel superficial

    OpenAIRE

    2012-01-01

    En la actualidad, el objetivo de la Didáctica de las Ciencias en Secundaria y Bachillerato es el conseguir que sus alumnos adquieran una competencia científica, para lo cual, ha de acercarles a su entorno. El trabajo que nos ocupa trata del Ciclo de las rocas, centrándose en las alteraciones que sufren las mismas al ascender a la superficie, ya que dicha superficie compone el entorno natural más inmediato del alumnado. Entre las distintas alteraciones que suceden tras ese ascen...

  6. Important risk factors and attributable risk of vertebral fractures in the population-based Tromsø study

    Directory of Open Access Journals (Sweden)

    Waterloo Svanhild

    2012-08-01

    Full Text Available Abstract Background Vertebral fractures, the most common type of osteoporotic fractures, are associated with increased risk of subsequent fracture, morbidity, and mortality. The aim of this study was to examine the contribution of important risk factors to the variability in vertebral fracture risk. Methods Vertebral fracture was ascertained by VFA method (DXA, GE Lunar Prodigy in 2887 men and women, aged between 38 and 87 years, in the population-based Tromsø Study 2007/2008. Bone mineral density (BMD; g/cm2 at the hip was measured by DXA. Lifestyle information was collected by questionnaires. Multivariable logistic regression model, with anthropometric and lifestyle factors included, was used to assess the association between each or combined risk factors and vertebral fracture risk. Population attributable risk was estimated for combined risk factors in the final multivariable model. Results In both sexes, age (odds ratio [OR] per 5 year increase: 1.32; 95% CI 1.19-1.45 in women and 1.21; 95% CI 1.10-1.33 in men and BMD (OR per SD decrease: 1.60; 95% CI 1.34-1.90 in women and1.40; 95% CI 1.18-1.67 in men were independent risk factors for vertebral fracture. At BMD levels higher than 0.85 g/cm2, men had a greater risk of fracture than women (OR 1.52; 95% CI 1.14-2.04, after adjusting for age. In women and men, respectively, approximately 46% and 33% of vertebral fracture risk was attributable to advancing age (more than 70 years and low BMD (less than 0.85 g/cm2, with the latter having a greater effect than the former. Conclusions These data confirm that age and BMD are major risk factors for vertebral fracture risk. However, in both sexes the two factors accounted for less than half of fracture risk. The identification of individuals with vertebral fracture is still a challenge.

  7. Improving interMediAte Risk management. MARK study

    Directory of Open Access Journals (Sweden)

    Garcia-Gil Maria

    2011-10-01

    Full Text Available Abstract Background Cardiovascular risk functions fail to identify more than 50% of patients who develop cardiovascular disease. This is especially evident in the intermediate-risk patients in which clinical management becomes difficult. Our purpose is to analyze if ankle-brachial index (ABI, measures of arterial stiffness, postprandial glucose, glycosylated hemoglobin, self-measured blood pressure and presence of comorbidity are independently associated to incidence of vascular events and whether they can improve the predictive capacity of current risk equations in the intermediate-risk population. Methods/Design This project involves 3 groups belonging to REDIAPP (RETICS RD06/0018 from 3 Spanish regions. We will recruit a multicenter cohort of 2688 patients at intermediate risk (coronary risk between 5 and 15% or vascular death risk between 3-5% over 10 years and no history of atherosclerotic disease, selected at random. We will record socio-demographic data, information on diet, physical activity, comorbidity and intermittent claudication. We will measure ABI, pulse wave velocity and cardio ankle vascular index at rest and after a light intensity exercise. Blood pressure and anthropometric data will be also recorded. We will also quantify lipids, glucose and glycosylated hemoglobin in a fasting blood sample and postprandial capillary glucose. Eighteen months after the recruitment, patients will be followed up to determine the incidence of vascular events (later follow-ups are planned at 5 and 10 years. We will analyze whether the new proposed risk factors contribute to improve the risk functions based on classic risk factors. Discussion Primary prevention of cardiovascular diseases is a priority in public health policy of developed and developing countries. The fundamental strategy consists in identifying people in a high risk situation in which preventive measures are effective and efficient. Improvement of these predictions in our country

  8. Study of occupation health risk assessment on Chinese coal mine

    Institute of Scientific and Technical Information of China (English)

    XIAO Guo-qing; YAN Xiang-nong

    2007-01-01

    Factors of occupation health hazard were identified and analyzed, and indexes system of occupation health risk assessment were established by applying fuzzy theory and system safety technique, the weights of index system were obtained by AHP, finally a reasonable mathematics model of occupation health risk assessment was accomplished by an example.

  9. Kidney Measures with Diabetes and Hypertension on Cardiovascular Disease : The Atherosclerosis Risk in Communities Study

    NARCIS (Netherlands)

    Alexander, Nadine; Matsushita, Kunihiro; Sang, Yingying; Ballew, Shoshana; Mahmoodi, Bakhtawar K.; Astor, Brad C.; Coresh, Josef

    2015-01-01

    Background: Whether the association of chronic kidney disease (CKD) with cardiovascular risk differs based on diabetes mellitus (DM) and hypertension (HTN) status remains unanswered. Methods: We investigated 11,050 participants from the Atherosclerosis Risk in Communities Study (fourth examination (

  10. NATO Advanced Study Institute on Insurance and Risk Theory

    CERN Document Server

    Vylder, F; Haezendonck, J

    1986-01-01

    Canadian financial institutions have been in rapid change in the past five years. In response to these changes, the Department of Finance issued a discussion paper: The Regulation of Canadian Financial Institutions, in April 1985, and the government intends to introduce legislation in the fall. This paper studi.es the combinantion of financial institutions from the viewpoint of ruin probability. In risk theory developed to describe insurance companies [1,2,3,4,5J, the ruin probability of a company with initial reserve (capital) u is 6 1 -:;-7;;f3 u 1jJ(u) = H6 e H6 (1) Here,we assume that claims arrive as a Poisson process, and the claim amount is distributed as exponential distribution with expectation liS. 6 is the loading, i.e., premium charged is (1+6) times expected claims. Financial institutions are treated as "insurance companies": the difference between interest charged and interest paid is regarded as premiums, loan defaults are treated as claims.

  11. Cognition and Vascular Risk Factors: An Epidemiological Study

    Directory of Open Access Journals (Sweden)

    Augusto Vicario

    2012-01-01

    Full Text Available We conducted an epidemiological approach to identify the negative impact of the vascular risk factors (such as hypertension, diabetes and hypercholesterolemia over cognition. The interesting aspect of this study was that the survey was conducted in all age groups through a voluntary call (n=1365; ≥18 years old, both sexes; age 49 ± 15 y, female 75.7%. Thus, we demonstrated that the use of a Minimum Cognitive Examination (MCE, a brief, simple, and easy managed neuropsychological evaluation, detected a greater number of people with cognitive decline surpassing to the Minimal Mental Statement Examination alone (14.5% of the participants showed MMSE ≤24, 34,6% showed dys-executive function, and 45,8% memory impairment. Out of the 4 studied RF, the only one that was not related to cognitive impairment was dyslipemia. Finally, we noted the importance of cognitive state early detection in all age groups, even in the youngest group. Acting in the middle of the life stages, we can prevent or delay the onset of a disease in adults, nowadays incurable: dementia.

  12. Green tea consumption and lung cancer risk: the Ohsaki study.

    Science.gov (United States)

    Li, Q; Kakizaki, M; Kuriyama, S; Sone, T; Yan, H; Nakaya, N; Mastuda-Ohmori, K; Tsuji, I

    2008-10-07

    We examined the risk of lung cancer in relation to green tea consumption in a population-based cohort study in Japan among 41,440 men and women, aged 40-79 years, who completed a questionnaire in 1994 regarding green tea consumption and other health-related lifestyle factors. During the follow-up period of 7 years (from 1995 to 2001), 302 cases of lung cancer were identified, and the Cox proportional hazards regression model was used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs). The multivariable-adjusted HRs of lung cancer incidence for green tea consumption of 1 or 2, 3 or 4, and 5 or more cups/day as compared to less than 1 cup/day were 1.14 (95% CI: 0.80-1.62), 1.18 (95% CI: 0.83-1.66), and 1.17 (95% CI: 0.85-1.61), respectively (P for trend=0.48). This cohort study has found no evidence that green tea consumption is associated with lung cancer.

  13. Study on Risk Approaches in Software Development Projects

    Directory of Open Access Journals (Sweden)

    Claudiu BRANDAS

    2012-01-01

    Full Text Available Risk approaches in project development led to the integration in the IT project management methodologies and software development of activities and processes of risk management. The diversity and the advanced level of the used technologies in IT projects with increasing com-plexity leads to an exponential diversification of risk factors.The purpose of this research is to identify the level of the risk approach in IT projects both at the IT project management and software development methodologies level and the level of the perception of IT project man-agers, IT managers and IT analysts in Romanian IT companies. Thus, we want to determine the correlation between the use of a project management or software development methodology and the overall level of risk perceived by the project managers using these methodologies.

  14. The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study

    DEFF Research Database (Denmark)

    Akerblom, H K; Krischer, J; Virtanen, Virpi Susanna;

    2011-01-01

    The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study was designed to establish whether weaning to a highly hydrolysed formula in infancy subsequently reduces the risk of type 1 diabetes.......The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study was designed to establish whether weaning to a highly hydrolysed formula in infancy subsequently reduces the risk of type 1 diabetes....

  15. Dança nos ciclos de escolarização: aproximações teóricas Dance in the School Cycles: Theoretical Approaches Danza en los Ciclos de Escolarización: Aproximaciones Teóricas

    Directory of Open Access Journals (Sweden)

    2006-11-01

    Full Text Available A proposta do texto é iniciar uma análise sobre o conteúdo Dança e os ciclos de escolarização, à luz de uma revisão bibliográfica. Buscaremos refletir acerca da sistematização do conhecimento a partir da referência teórica que mais bem organiza, no nosso entendimento, o trato pedagógico da Educação Física Escolar, uma proposta de Soares et al. (1992. Analisaremos, também, as propostas da dança na escola sugeridas por Marques (1999, Gehres (1996 e Xarez et al. (1992. Nosso objetivo é traçar uma reflexão acerca deste conteúdo numa abordagem que mais se aproxime da sistematização em ciclos de conhecimento, além de ampliá-la. Serão destacadas as possibilidades de conquistas e dificuldades. PALAVRAS-CHAVE: Escola - Dança - Ciclos de sistematização do conhecimento. This study aims at starting an analysis about Dance and School Cycles, through a biblographical review. We will try to reflect upon this systematization from the theoretical reference that best organizes this body of knowledge, which is, in our view, the pedagocial approach of School Physical Education, which is proposed by Soares et all (1992. We also intend to analyze school dance projects suggested by Marques (1999, Gehres (1996 and Xarez et all (1992, and try to establish a reflection upon this content through an amplified approach that comes closer to the systematization in learning cycles, highlighting possibilites of achievements and overcoming of difficulties. KEY WORDS: School - Dance - Systematization of knowledge. La propuesta del texto es iniciar un análisis, sobre el contenido Danza y los ciclos de escolarización la luz de una revisión bibliográfica. Buscaremos reflexionar sobre esta sistematización a partir de la referencia teórica que mejor organice, desde nuestro punto de vista, el trato pedagógico de la Educación Física Escolar, que es la propuesta de Soares met all (1992, como también analizar propuestas de la danza en la

  16. Influencia do sexo, do ciclo estral e do estrese agudo nas respostas hormonais e metobolicas em ratos

    OpenAIRE

    Fabio Jose Bianchi

    2004-01-01

    Resumo: O objetivo deste trabalho foi analisar a influência do sexo e do ciclo estral nas respostas metabólicas e hormonais em ratos submetidos a estresse agudo. Ratos com 3 meses de idade, machos e fêmeas ovariectomizadas, ou com ciclo estral regular, foram usados (n = 7-11/grupo). Após a identificação da fase do ciclo estral, manipulação (machos) ou 21 dias após a castração, os animais foram submetidos a uma sessão de natação. Imediatamente após a aplicação do estresse, os animais foram ...

  17. Psicología del ciclo vital: hacia una visión comprehensiva de la vida humana

    Directory of Open Access Journals (Sweden)

    Elisa Dulcey Ruiz

    2002-01-01

    Full Text Available Se propone que la psicología del ciclo vital es más amplia que la psicología del desarrollo. Coherente con una visión integral del curso del ciclo vital esta psicología enfatiza la irrelevancia de la edad, los cambios permanentes, la multidimensionalidad, y la plasticidad, también como la importancia del contexto y la historia. Se refiere al proceso de envejecimiento, a la adultez, la vejez y la muerte en el marco del ciclo vital; enfatiza posibilidades relacionadas con el envejecimiento exitoso, el bienestar subjetivo y la sabiduría, acordes con el punto de vista de la psicología positiva y posibles de lograr mediante el aprendizaje durante toda la vida o la educación vitalicia.

  18. Psicología del ciclo vital: hacia una visión comprehensiva de la vida humana

    Directory of Open Access Journals (Sweden)

    Elisa Dulcey Ruiz

    2002-01-01

    Full Text Available Se propone que la psicología del ciclo vital es más amplia que la psicología del desarrollo. Coherente con una visión integral del curso del ciclo vital esta psicología enfatiza la irrelevancia de la edad, los cambios permanentes, la multidimensionalidad, y la plasticidad, también como la importancia del contexto y la historia. Se refiere al proceso de envejecimiento, a la adultez, la vejez y la muerte en el marco del ciclo vital; enfatiza posibilidades relacionadas con el envejecimiento exitoso, el bienestar subjetivo y la sabiduría, acordes con el punto de vista de la psicología positiva y posibles de lograr mediante el aprendizaje durante toda la vida o la educación vitalicia.

  19. The case study of climate change : the nature of risk and the risk of nature

    Energy Technology Data Exchange (ETDEWEB)

    Good, J. [Cornell Univ., Ithaca, NY (United States). Dept. of Communication

    2000-06-01

    The science of climate change is complex, large-scale and uncertain. The challenges of communicating the risks of climate change were described with particular emphasis on working with communities to explain climate change with its complex, scientific and social realities. The greenhouse effect is a feature of the earth in which a carbon dioxide blanket absorbs the sun's heat as it radiates off the earth. The paper stated that the greenhouse effect is arguably the best accepted theory in climatology, but the question is whether the huge increase in carbon dioxide that the industrial revolution has brought forth has increased the efficiency of this blanket and set the earth on a warming trend. The ultimate question is whether the earth is warming in response to human activity. It could be claimed that apart from the risk of nuclear war, the risk of climate change is the largest scale risk facing today's society. Climate change pits the burning of fossil fuels against the climate and as a modern day risk, climate change is far removed from the historic roots of environmental risks. The paper argued, that in a world based on burning fossil fuels and where those who are involved with the supply of fossil fuels hold tremendous influence, it is difficult to accept that the burning might have to stop. This paper explored how and what people currently learn about the environment and climate change through the media. A three-step communication strategy based in the United States was then proposed. The first step is aimed at journalists with focus on improved accuracy of climate change information. The second step focuses on urban centres and has as its guiding concepts self-efficacy, reasoned action and the importance of reaching people in diverse communities. The final step is aimed at political leaders, beginning with municipalities, and relies on campaigns for alternative energy.

  20. Combination of diabetes risk factors and hepatic steatosis in Chinese: the Cardiometabolic Risk in Chinese (CRC Study.

    Directory of Open Access Journals (Sweden)

    Jun Liang

    Full Text Available AIMS: Hepatic steatosis has been related to insulin resistance and increased diabetes risk. We assessed whether combination of diabetes risk factors, evaluated by the Finnish Diabetes Risk Score, was associated with risk of hepatic steatosis in an apparently healthy Chinese population. RESEARCH DESIGN AND METHODS: The study samples were from a community-based health examination survey in central China. In total 1,780 men and women (18-64 y were included in the final analyses. Hepatic steatosis was diagnosed by ultrasonography. We created combination of diabetes risk factors score on basis of age, Body Mass Index, waist circumference, physical activity at least 4 h a week, daily consumption of fruits, berries or vegetables, history of antihypertensive drug treatment, history of high blood glucose. The total risk score is a simple sum of the individual weights, and values range from 0 to 20. RESULTS: Hepatic steatosis was present 18% in the total population. In multivariate models, the odds ratios of hepatic steatosis were 1.20 (95%CI 1.15-1.25 in men and 1.25 (95%CI 1.14-1.37 in women by each unit increase in the combination of diabetes risk factors score, after adjustment for blood pressure, liver enzymes, plasma lipids, and fasting glucose. The area under the receiver operating characteristic curve for hepatic steatosis was 0.78 (95%CI 0.76-0.80, 0.76 in men (95%CI 0.74-0.78 and 0.83 (95%CI 0.79-0.87 in women. CONCLUSIONS: Our data suggest that combination of major diabetes risk factors was significantly related to risk of hepatic steatosis in Chinese adults.

  1. Fotólise do ácido salicílico na presença de ciclo dextrina = Photolisys of the salicylic acid in the presence of â-cyclodextrin

    Directory of Open Access Journals (Sweden)

    Reinaldo Aparecido Bariccatti

    2005-01-01

    Full Text Available Neste trabalho, utilizou-se a espectroscopia de UV/VIS para estudar afotodegradacao por luz UV do acido salicilico em cavidade de ƒÀ-ciclo dextrina. Verificou-se uma reducao na velocidade de fotodegradacao do acido salicilico de 34,5% em pH 7 e de 17,5% em pH 4 quando se adiciona a ƒÀ-ciclo dextrina na solucao. O valor obtido para aconstante de dissociacao do complexo acido salicilico e ƒÀ-ciclo dextrina foi de 4,3}0,5 L10-3 mol/L.In this work the UV/VIS spectroscopy was used to study the photo degradation by UV light of the salicylic acid in cavity of ƒÀ-cyclodextrin. A reduction in the speed of degradation of thesalicylic acid of 34.5% in pH 7 and of 17.5% in pH 4 was observed when ƒÀ-cyclodextrin is added to the solution. The obtained value to the constant of dissociation of the salicylic acid complex and of the ƒÀ-cyclodextrin was of 4.3}0.5x10-3 mol/L.

  2. LA CALCULADORA CIENTIFICA Y LA OBTENCIÓN DE LA RESPUESTA CORRECTA EN EL CICLO DIVERSIFICADO

    Directory of Open Access Journals (Sweden)

    José Ángel García Retana

    2009-01-01

    Full Text Available Al comparar la Política Educativa costarricense con los Planes y Programas en Matemáticas, desarrollados en el ciclo diversificado, se muestra una discrepancia en torno a los objetivos de éstos. La Política Educativa propone un aprendizaje con comprensión sobre la base del paradigma constructivista, en tanto los Planes y Programas pretenden dotar al educando de recursos para la obtención de respuestas correctas, incluyendo para ello el uso de la calculadora científica. Esta discrepancia muestra una diferencia significativa en el éxito en la prueba de Bachillerato (conclusión del ciclo diversificado entre los ítemes "algorítmicos" (los cuales pueden ser resueltos con el apoyo de la calculadora científica, y los "conceptuales". Esta diferencia se incrementa en la Prueba de Diagnóstico que muchos estudiantes aplican antes de ingresar a la Universidad de Costa Rica, dado que en la misma no pueden utilizar la calculadora científica. El presente ensayo cuestiona un posible papel de la calculadora científica en esta situación.

  3. Moeda, crédito e ciclos econômicos em Marshall

    Directory of Open Access Journals (Sweden)

    Sérgio Fornazier Meyrelles Filho

    2016-03-01

    Full Text Available Resumo Este artigo tem por objetivo examinar os elementos centrais da análise de Alfred Marshall sobre as flutuações cíclicas, contemplando o papel da especulação e do crédito nesse contexto. A primeira seção contém breve introdução ao assunto. A seguir, tratam-se das contribuições de Marshall sobre os determinantes das taxas de juros normal e de mercado, bem como a sua reformulação da Teoria Quantitativa da Moeda. Após, apresenta-se a sua explicação dos ciclos econômicos, na qual se articulam em uma mesma estrutura os elementos teóricos expostos nas seções anteriores. Ao final, uma comparação da teoria monetária de Marshall com as contribuições de Irving Fisher e Knut Wicksell é realizada, destacando-se os pontos de contato, bem como de distanciamento, entre esses proeminentes teóricos neoclássicos dos fenômenos monetários. Elabora-se ainda uma versão dinâmica formal do modelo marshalliano dos ciclos, incluída em apêndice.

  4. Ciclo de vida de Pellaea ternifolia (Cav. Link subsp. ternifolia (Pteridaceae-Polypodiidae

    Directory of Open Access Journals (Sweden)

    Jorge Huerta-Zavala

    2015-08-01

    Full Text Available Se describe el ciclo de vida dePellaea ternifolia(Cav. Link subsp.ternifolia. Los especímenes fueron recolectados en un bosque dePinusperturbado en San Miguel de los Alcanfores, municipio de Tlaxco, Tlaxcala, México. Las esporas fueron sembradas en vasos de unicel de 262 ml con cerámica (barro molido, piedra de río, tela de mosquitero y tres soportes de cultivo (tierra, maquique y musgo, todo previamente esterilizado y cerrado con plástico y alambre de cobre. El ciclo fue isospórico con desarrollo del protalo tipoAdiantum. En la fase cordada se apreciaron gametófitos con anteridios y arquegonio en una proporción cercana al 70% y el otro 30% fueron gametófitos apogámicos. Los esporófitos jóvenes se obtuvieron a partir de los 63 días.

  5. Estudo comparativo do ciclo evolutivo de Rhodnius neglectus alimentados em pombos ou camundongos

    Directory of Open Access Journals (Sweden)

    Liléia Diotaiuti

    1987-06-01

    Full Text Available Baseados no encontro de 77,2% de reação de precipitina positiva para soro antiave de R. neglectus capturados em palmeiras da periferia de Belo Horizonte, estudamos o ciclo evolutivo de uma colonia recém-estabelecida no laboratório alimentada com sangue de pombo ou camundongo, na expectativa de demonstrarmos maior adaptação deste triatomíneo ao sangue da ave. Para comparação, estudamos o ciclo evolutivo destes insetos numa colônia há muito mantida em insetário. Nossos resultados mostram um desenvolvimento mais rápido da colônia recém- estabelecida, assim como do lote de triatomíneos alimentado em camundongo. Esses achados sugerem menor potencial biológico para triatomíneos criados por longo tempo em insetário em comparação a novas colônias. Sendo as aves os principais habitantes das palmeiras, a aparente preferência alimentar por sangue de aves demonstrada pela reação de precipitina parece ser circunstancial e não seletiva na busca do sangue com o qual o triatomíneo obteria melhor desenvolvimento.

  6. Mixture risk assessment: a case study of Monsanto experiences.

    Science.gov (United States)

    Nair, R S; Dudek, B R; Grothe, D R; Johannsen, F R; Lamb, I C; Martens, M A; Sherman, J H; Stevens, M W

    1996-01-01

    Monsanto employs several pragmatic approaches for evaluating the toxicity of mixtures. These approaches are similar to those recommended by many national and international agencies. When conducting hazard and risk assessments, priority is always given to using data collected directly on the mixture of concern. To provide an example of the first tier of evaluation, actual data on acute respiratory irritation studies on mixtures were evaluated to determine whether the principle of additivity was applicable to the mixture evaluated. If actual data on the mixture are unavailable, extrapolation across similar mixtures is considered. Because many formulations are quite similar in composition, the toxicity data from one mixture can be extended to a closely related mixture in a scientifically justifiable manner. An example of a family of products where such extrapolations have been made is presented to exemplify this second approach. Lastly, if data on similar mixtures are unavailable, data on component fractions are used to predict the toxicity of the mixture. In this third approach, process knowledge and scientific judgement are used to determine how the known toxicological properties of the individual fractions affect toxicity of the mixture. Three examples of plant effluents where toxicological data on fractions were used to predict the toxicity of the mixture are discussed. The results of the analysis are used to discuss the predictive value of each of the above mentioned toxicological approaches for evaluating chemical mixtures.

  7. Ciclo de vida de Anasa litigiosa (Hemiptera: Heteroptera: Coreidae Life cycle of Anasa litigiosa (Hemiptera: Heteroptera: Coreidae

    Directory of Open Access Journals (Sweden)

    Adriana Chacón-López

    2012-06-01

    Full Text Available El objetivo de este trabajo es el estudio del ciclo de vida de Anasa litigiosa Stål. Se recolectaron ejemplares adultos de esta especie que se encontraban sobre plantas de chayote y fueron cultivados en el laboratorio utilizando hojas, tallos y frutos de la misma planta. Se describen e ilustran en detalle todos los estadios de vida, incluyendo notas sobre su biología. Anasa litigiosa se ha recolectado sobre bromeliáceas y cucurbitáceas y es una plaga importante de estas últimas.The aim of this work was the study of the life cycle of Anasa litigiosa Stål. Adults were collected on chayote and they were reared in laboratory using leaves, stems and fruits of chayote. Descriptions and illustrations of all instars of, and notes on its biology are included. This species has been collected in bromeliads and on cucurbits, it is an important pest of cucurbits in Mexico.

  8. Leprosy among patient contacts: a multilevel study of risk factors.

    Directory of Open Access Journals (Sweden)

    Anna M Sales

    Full Text Available BACKGROUND: This study aimed to evaluate the risk factors associated with developing leprosy among the contacts of newly-diagnosed leprosy patients. METHODOLOGY/PRINCIPAL FINDINGS: A total of 6,158 contacts and 1,201 leprosy patients of the cohort who were diagnosed and treated at the Leprosy Laboratory of Fiocruz from 1987 to 2007 were included. The contact variables analyzed were sex; age; educational and income levels; blood relationship, if any, to the index case; household or non-household relationship; length of time of close association with the index case; receipt of bacillus Calmette-Guérin (BGG vaccine and presence of BCG scar. Index cases variables included sex, age, educational level, family size, bacillary load, and disability grade. Multilevel logistic regression with random intercept was applied. Among the co-prevalent cases, the leprosy-related variables that remained associated with leprosy included type of household contact, [odds ratio (OR = 1.33, 95% confidence interval (CI: 1.02, 1.73] and consanguinity with the index case, (OR = 1.89, 95% CI: 1.42-2.51. With respect to the index case variables, the factors associated with leprosy among contacts included up to 4 years of schooling and 4 to 10 years of schooling (OR = 2.72, 95% CI: 1.54-4.79 and 2.40, 95% CI: 1.30-4.42, respectively and bacillary load, which increased the chance of leprosy among multibacillary contacts for those with a bacillary index of one to three and greater than three (OR = 1.79, 95% CI: 1.19-2.17 and OR: 4.07-95% CI: 2.73, 6.09, respectively. Among incident cases, household exposure was associated with leprosy (OR = 1.96, 95% CI: 1.29-2.98, compared with non-household exposure. Among the index case risk factors, an elevated bacillary load was the only variable associated with leprosy in the contacts. CONCLUSIONS/SIGNIFICANCE: Biological and social factors appear to be associated with leprosy among co-prevalent cases, whereas the factors related to the

  9. [Risk factor calculator for medical underwriting of life insurers based on the PROCAM study].

    Science.gov (United States)

    Geritse, A; Müller, G; Trompetter, T; Schulte, H; Assmann, G

    2008-06-01

    For its electronic manual GEM, used to perform medical risk assessment in life insurance, SCOR Global Life Germany has developed an innovative and evidence-based calculator of the mortality risk depending on cardiovascular risk factors. The calculator contains several new findings regarding medical underwriting, which were gained from the analysis of the PROCAM (Prospective Cardiovascular Münster) study. For instance, in the overall consideration of all risk factors of a medically examined applicant, BMI is not an independent risk factor. Further, given sufficient information, the total extra mortality of a person no longer results from adding up the ratings for the single risk factors. In fact, this new approach of risk assessment considers the interdependencies between the different risk factors. The new calculator is expected to improve risk selection and standard acceptances will probably increase.

  10. NOS3 polymorphisms, cigarette smoking, and cardiovascular disease risk: The Atherosclerosis Risk in Communities study

    Science.gov (United States)

    Endothelial nitric oxide synthase (NOS3) activity and cigarette smoking significantly influence endothelial function. We sought to determine whether cigarette smoking modified the association between NOS3 polymorphisms and risk of coronary heart disease or stroke. All 1085 incident coronary heart di...

  11. A prospective study of risk factors for foot ulceration: The West of Ireland Diabetes Foot Study.

    LENUS (Irish Health Repository)

    Hurley, L

    2013-09-25

    BackgroundThis is the first study to examine risk factors for diabetic foot ulceration in Irish general practice.AimTo determine the prevalence of established risk factors for foot ulceration in a community-based cohort, and to explore the potential for estimated glomerular filtration rate (eGFR) to act as a novel risk factor.DesignA prospective observational study.MethodsPatients with diabetes attending 12 (of 17) invited general practices were invited for foot screening. Validated clinical tests were carried out at baseline to assess for vascular and sensory impairment and foot deformity. Ulcer incidence was ascertained by patient self-report and medical record. Patients were re-assessed 18 months later. ResultsOf 828 invitees, 563 (68%) attended screening. On examination 23-25% had sensory dysfunction and 18-39% had evidence of vascular impairment. Using the Scottish Intercollegiate Guidelines Network risk stratification system we found the proportion at moderate and high risk of future ulceration to be 25% and 11% respectively. At follow-up 16\\/383 patients (4.2%) developed a new foot ulcer (annual incidence rate of 2.6%). We observed an increasing probability of abnormal vascular and sensory test results (pedal pulse palpation, doppler waveform assessment, 10g monofilament, vibration perception and neuropathy disability score) with declining eGFR levels. We were unable to show an independent association between new ulceration and reduced eGFR [Odds ratio 1.01; p=0.64].ConclusionsOur data show the extent of foot complications in a representative sample of diabetes patients in Ireland. Use of eGFR did not improve identification of patients at risk of foot ulceration.

  12. La crisis del ciclo neoliberal en los países de la región andina

    OpenAIRE

    Eudis F. Fermín T.

    2010-01-01

    En el artículo se estudia la crisis del ciclo neoliberal en los países de la Región Andina en el contexto delos cambios políticos latinoamericanos. Es una investigación documental-analítica, fundamentada en una revisión bibliográfica y en la clasificación del material para el procesamiento de los datos recolectados, la interpretación de esos datos parte de la categoría crisis del ciclo neoliberal. El neoliberalismo reduce las funciones de los Estados andinos a las áreas medulares: educación, ...

  13. Auditoría de la gestión del ciclo de vida del software como servicio tercerizado (outsourcing)

    OpenAIRE

    Rosales Alpízar, Carmen Lisset

    2015-01-01

    Tesis de maestría -- Universidad de Costa Rica. Posgrado en Administración y Dirección de Empresas. Maestría Profesional en Auditoría de Tecnologías de Información, 2015 El presente documento es una recopilación del trabajo realizado a lo largo de las fases del ciclo de auditoría de la gestión del ciclo de vida del software como servicio tercerizado (outsourcing). El objetivo del mismo busca responder a la necesidad de obtener un programa de auditoría aplicable a los procesos de gestión de...

  14. Sensibilidade as catecolaminas dos atrios direitos das ratas : influencia das fases do ciclo estral e do "stress"

    OpenAIRE

    Monica Luiza Viegas Rodrigues

    1993-01-01

    Resumo: Os objetivos deste trabalho foram: analisar a sensibilidade ao efeito cronotrópico da isoprenalina, noradrenalina e adrenalina de átrios direitos isolados de ratas normais, em cada uma das fases do ciclo estral, ou após 50 minutos de natação, durante o estro ou o diestro; correlacionar as alterações de sensibilidade com as fases do ciclo estral e/ou com os níveis plasmáticos de corticosterona. Utilizamos ratas adultas, Wistar, normais, sedentárias, ou imediatamente após 50 min de nata...

  15. EFEITO DE INTERMEDIÁRIOS DO CICLO DE KREBS SOBRE ALTERAÇÕES OXIDATIVAS INDUZIDAS POR DIFERENTES AGENTES OXIDANTES

    OpenAIRE

    2006-01-01

    Dados recentes na literatura têm relatado que alguns intermediários do ciclo de Krebs podem agir como potentes antioxidantes, tanto in vitro, quanto in vivo, em diversos sistemas pró-oxidantes. Porém, o(s) mecanismo(s) através dos qual(is) os intermediários do ciclo de Krebs exercem suas atividades antioxidantes não são completamente entendidas. Considerando a escassez de dados in vitro na literatura a respeito do efeito desses intermediários durante situações de estresse oxidativo, o present...

  16. Modelo estocástico para planificar cadenas de suministro con productos de ciclos de vida cortos

    Directory of Open Access Journals (Sweden)

    Jairo Coronado-Hernandez

    2010-07-01

    Full Text Available En este trabajo se presenta un modelo de optimización estocástica para la planificación de cadenas de suministros para productos con ciclo de vida corto, a través de la decisión de reservar la capacidad a contratar en los recursos de los proveedores antes de tener certeza del comportamiento de la demanda. Se consideran recursos alternativos, múltiples productos con lista de materiales complejas, demanda distribuida a lo largo de periodos consecutivos, ciclos de vida cortos, lead time largos y altos niveles de incertidumbre representados en forma de escenarios.

  17. Niveles plasmáticos de beta-endorfina en el ciclo menstrual y en la dismenorrea

    OpenAIRE

    2015-01-01

    Se realiza la valoración de las concentraciones plasmáticas de beta-endorfina en el ciclo menstrual y en la mujer dismenorreica, para lo que se estudian un grupo de jóvenes fértiles, todas ellas voluntarias, no estando ninguna sometida a tratamiento hormonal ni a anticoncepción. La sangre obtenida en días concretos del ciclo por punción venosa es analizada por RIA para obtener las concentraciones del opiáceo, determinándose las gonadotropinas y los esteroides ováricos por ELISA. La beta-endor...

  18. Sistemas neurales de retroalimentación durante el ciclo reproductivo anual de la oveja: una revisión

    OpenAIRE

    Jaime Arroyo Ledezma; Jaime Gallegos-Sánchez; Alejandro Villa Godoy; Javier Valencia Méndez

    2006-01-01

    El ciclo reproductivo anual de la oveja es regulado por la amplitud del fotoperiodo. La señal luminosa se traduce en una señal hormonal a través de la síntesis de melatonina. La disminución en la duración del fotoperiodo induce la actividad reproductiva y el aumento en las horas luz, inhibe la actividad ovulatoria estral, la conducta de estro y la ovulación (anestro estacional). Durante la época reproductiva, la progesterona (P4) regula los ciclos estrales de la oveja inhibiendo la secreción ...

  19. Implicaciones del estudio de inestabilidad del ciclo celular en la biología del cáncer.

    OpenAIRE

    Luis Tume-Farfán

    2014-01-01

    Todas las células poseen mecanismos para mantener la integridad genómica que es vital para la supervivencia celular y la proliferación. Las células se dividen a tasas normale s durante su tiempo de vida, cuando esta tasa sobrepasa los límites normales ocurren alteraciones a nivel genético que afectan el control del ciclo celular por lo tanto estas células crecen y se dividen sin control y ya no responden a señalización extrace lular que indica la detención del ciclo y la apoptosis, estos meca...

  20. RISK COMMUNICATION IN ACTION: CASE STUDIES IN FISH ADVISORIES

    Science.gov (United States)

    This Handbook provides both general and specific information on how to enhance mercury risk communication activities and their associated outreach efforts. Additionally, it provides information on how to facilitate communication in areas where information is not available. Chapte...

  1. Empirical Study of the Risks in Shenzhen Stock Market

    Institute of Scientific and Technical Information of China (English)

    ZUO Xiao-de; GAO Wei-cun

    2001-01-01

    This paper conducts an empirical research on the system risks of the Shenzhen Stock Market using Capital Asset Pricing Model. The typical composition stocks on Shenzhen Stock Market in 1998 are taken as samples.

  2. Disabled Kids At Higher Risk of Abuse, Study Finds

    Science.gov (United States)

    ... Certain conditions linked to greater odds for neglect, bullying To use the sharing features on this page, ... also suggest those risks vary depending on the type of disorder a child has. "We've known ...

  3. Analysing truck position data to study roundabout accident risk

    OpenAIRE

    Kamla, Jwan Jameel Shekh Mohammed

    2016-01-01

    In order to reduce accident risk, highway authorities prioritise maintenance budgets partly based upon previous accident history. However, as accident rates have continued to fall in most contexts, this approach has become problematic as accident ‘black spots’ have been treated and the number of accidents at any individual site has fallen. Another way of identifying sites of higher accident risk might be to identify near-miss accidents (where an accident nearly happened, but was avoided), whi...

  4. Putative Risk Factors in Developmental Dyslexia: A Case-Control Study of Italian Children

    Science.gov (United States)

    Mascheretti, Sara; Marino, Cecilia; Simone, Daniela; Quadrelli, Ermanno; Riva, Valentina; Cellino, Maria Rosaria; Maziade, Michel; Brombin, Chiara; Battaglia, Marco

    2015-01-01

    Although dyslexia runs in families, several putative risk factors that cannot be immediately identified as genetic predict reading disability. Published studies analyzed one or a few risk factors at a time, with relatively inconsistent results. To assess the contribution of several putative risk factors to the development of dyslexia, we conducted…

  5. Risk Management for Study Abroad Programs: Issues and Resources to Inform Program Development, Administration, and Training

    Science.gov (United States)

    Rhodes, Gary

    2014-01-01

    This chapter provides a practical background to the health and safety risks and challenges for U.S. colleges and universities and other program providers. Potential risks, field-based guidelines, good practices, and resources to support the management of risks by study abroad offices will be covered.

  6. Prevalence and risk indicators of depression in elderly nursing home patients : the AGED study

    NARCIS (Netherlands)

    Jongenelis, K; Eisses, AMH; Beekman, ATF; Kluiter, H; Ribbe, MW

    2004-01-01

    Background: Depression is a common and disabling psychiatric disorder in later life. Particular frail nursing home patients seem to be at increased risk. Nursing home-based studies on risk indicators of depression are scarce. Methods: Prevalence and risk indicators of depression were assessed in 333

  7. Behavioral Inhibition and Risk for Developing Social Anxiety Disorder: A Meta-Analytic Study

    Science.gov (United States)

    Clauss, Jacqueline A.; Blackford, Jennifer Urbano

    2012-01-01

    Objective: Behavioral inhibition (BI) has been associated with increased risk for developing social anxiety disorder (SAD); however, the degree of risk associated with BI has yet to be systematically examined and quantified. The goal of the present study was to quantify the association between childhood BI and risk for developing SAD. Method: A…

  8. Suicide and mental illness in parents and risk of suicide in offspring: a birth cohort study

    DEFF Research Database (Denmark)

    Sørensen, Holger J; Mortensen, Erik L; Wang, August G

    2009-01-01

    BACKGROUND: A family history of completed suicide and psychiatric illness has been identified as risk factors for suicide. AIMS: To examine the risk of offspring suicide in relation to parental history of suicide and other parental risk factors. METHOD: The study population consisted of 7,177 adu...

  9. Work-site musculoskeletal pain risk estimates by trained observers--a prospective cohort study.

    Science.gov (United States)

    Coenen, Pieter; Kingma, Idsart; Boot, Cécile R L; Douwes, Marjolein; Bongers, Paulien M; van Dieën, Jaap H

    2012-01-01

    Work-related musculoskeletal pain (MSP) risk assessments by trained observers are often used in ergonomic practice; however, the validity may be questionable. We investigated the predictive value of work-site MSP risk estimates in a prospective cohort study of 1745 workers. Trained observers estimated the risk of MSP (neck, shoulder or low-back pain) using a three-point scale (high, moderate and low risk) after observing a video of randomly selected workers representing a task group. Associations of the estimated risk of pain and reported pain during a three-year follow-up were assessed using logistic regression. Estimated risk of neck and shoulder pain did (odds ratio, OR: 1.45 (95% confidence interval, CI: 1.01-2.08); 1.64 (95% CI: 1.05-2.55)), however, estimated risk of low-back pain did not significantly predict pain (OR: 1.27 (95% CI: 0.91-1.79)). The results show that observers were able to estimate the risk of shoulder and neck pain, whereas they found it difficult to estimate the risk of low-back pain. Practitioner Summary: Work-related musculoskeletal pain risk assessments by observers are often used in ergonomic practice. We showed that observers were able to estimate shoulder and neck pain risk, but had difficulties to estimate the risk of low-back pain. Therefore, observers' risk estimates might provide a useful method for musculoskeletal pain risk assessments.

  10. Study of the associated factors risks in specialist library in Lara state, Venezuela

    Directory of Open Access Journals (Sweden)

    Leomar Montilla Peña

    2016-11-01

    Full Text Available Presented are the results of a study on the risk factors associated to a specialized library in Lara State, Venezuela. The objective of this research was to analyze the risk factors that may represent sources of hazards in all elements of the organization of information. The research is descriptive, field and quasi-experimental. Was performed identification the of risk factors and risk quantification was performed by the probability (frequency and intensity (severity that can produce the harmful effects. The results indicate that 25 of the 32 analyzed risk factors may be related to the element of information sources, also in the same way 12 of the 32 may be associated risk factors with human talent element, 12 of the 32 risk factors with user element, 12 of the 32 risk factors with the building element and 10 of the 32 risk factors with the equipments element. The study conclusions show that the risk factors that require further attention and priority, are: relative humidity (risk value 45, dust (risk value 45 and technical cleaning preventive (risk value 15.

  11. Breast cancer risk perceptions of Turkish women attending primary care: a cross-sectional study

    OpenAIRE

    Kartal, Mehtap; Ozcakar, Nilgun; Hatipoglu, Sehnaz; Tan, Makbule Neslisah; Guldal, Azize Dilek

    2014-01-01

    Background As the risks and benefits of early detection and primary prevention strategies for breast cancer are beginning to be quantified, the risk perception of women has become increasingly important as may affect their screening behaviors. This study evaluated the women’s breast cancer risk perception and their accuracy, and determined the factors that can affect their risk perception accuracy. Methods Data was collected in a cross-sectional survey design. Questionnaire, including breast ...

  12. Liquidity Risk on Banking Industry: Comparative Study Between Islamic Bank and Conventional Bank in Indonesia

    OpenAIRE

    Harjum Muharam; Hasna Penta Kurnia

    2015-01-01

    Conventional and Islamic banks approximately are similar in risk summary. Therefore it needs further observations to control their liquidity risk. This study investigates the influence of CAR, profitability rasios, NIM, liquidity gaps, and RLA belongs to liquidity risk on banking industry. The statistical analysis concluded that there are negative and significant influence of CAR and ROE to liquidity risk on conventional banks, while ROA and RLA have positive and significant effect. In Islami...

  13. Guidelines for contingency planning NASA (National Aeronautics and Space Administration) ADP security risk reduction decision studies

    Science.gov (United States)

    Tompkins, F. G.

    1984-01-01

    Guidance is presented to NASA Computer Security Officials for determining the acceptability or unacceptability of ADP security risks based on the technical, operational and economic feasibility of potential safeguards. The risk management process is reviewed as a specialized application of the systems approach to problem solving and information systems analysis and design. Reporting the results of the risk reduction analysis to management is considered. Report formats for the risk reduction study are provided.

  14. Risk of caries and oral health: preliminary study

    Directory of Open Access Journals (Sweden)

    Marcello Gatti

    2009-12-01

    Full Text Available Introduction. The incidence of injury cariosa remains high, despite the improvements achieved in the last years. Recent national epidemiological surveys, 4 years old children have healthy teeth in 80% of cases at 12 years the percentage is reduced to 50%. In Italy, the almost total absence on the territory of “dental services to the Community”, makes even more difficult to achieve a solution to the problem “caries.” To address this problem, the Ministry of Labor, Health and Social Policy in October 2008 adopted the national guidelines in order to make suggestions to the various professionals (pediatricians, dentists, microbiologists, dental hygienists, etc., making them interact to maintain and restore oral health. It was the first time that the Ministry of Health has addressed the problem by inserting the figure of the microbiologist in dentistry. Aims. The present study aim was to identify subjects at risk of caries by clinical microbiological testing of saliva and the index DMFT/dmft (Decayed, Missing and Filling Permanent Teeth in both adults and particularly children in order to take preventive measures early as reported in “National guidelines for the promotion of oral health and prevention of oral diseases in age of development”. The study began in June 2009 and will last one year with as goal to have, in 2010, 90% of children between 5 and 6 years caries free and 18 years with any lost tooth decay. Materials and methods. Recruited 164 patients were divided into three age groups: 124 adults aged between 20 and 40 years, 40 children which 21 till 5 years old and 19 till 12 years old. Microbiological testing was aimed by finding CFU / ml of saliva of Streptococcus mutans and Lactobacillus spp., Slide CRT bacteria (Ivoclar. Clinically, intraoral examination was performed to evaluate the DMFT (Decayed teeth, Missing or Filling calculated over 28 permanent teeth and the dmft (decayed teeth, missing or filling calculated on 20

  15. Radiation, Atherosclerotic Risk Factors, and Stroke Risk in Survivors of Pediatric Cancer: A Report From the Childhood Cancer Survivor Study

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Sabine, E-mail: muellers@neuropeds.ucsf.edu [Department of Neurology, Pediatrics and Neurosurgery, University of California, San Francisco, San Francisco, California (United States); Fullerton, Heather J. [Department of Neurology and Pediatrics, University of California, San Francisco, San Francisco, California (United States); Stratton, Kayla; Leisenring, Wendy [Fred Hutchinson Cancer Research Center, Seattle, Washington (United States); Weathers, Rita E.; Stovall, Marilyn [Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Armstrong, Gregory T. [St. Jude Children' s Research Hospital, Memphis, Tennessee (United States); Goldsby, Robert E. [Department of Pediatrics, University of California, San Francisco, San Francisco, California (United States); Packer, Roger J. [Children' s National Medical Center, Washington, District of Columbia (United States); Sklar, Charles A. [Memorial Sloan-Kettering Cancer Center, New York, New York (United States); Bowers, Daniel C. [University of Texas Southwestern Medical School, Dallas, Texas (United States); Robison, Leslie L.; Krull, Kevin R. [St. Jude Children' s Research Hospital, Memphis, Tennessee (United States)

    2013-07-15

    Purpose: To test the hypotheses that (1) the increased risk of stroke conferred by childhood cranial radiation therapy (CRT) persists into adulthood; and (2) atherosclerotic risk factors further increase the stroke risk in cancer survivors. Methods and Materials: The Childhood Cancer Survivor Study is a multi-institutional retrospective cohort study of 14,358 5-year survivors of childhood cancer and 4023 randomly selected sibling controls with longitudinal follow-up. Age-adjusted incidence rates of self-reported late-occurring (≥5 years after diagnosis) first stroke were calculated. Multivariable Cox proportional hazards models were used to identify independent stroke predictors. Results: During a mean follow-up of 23.3 years, 292 survivors reported a late-occurring stroke. The age-adjusted stroke rate per 100,000 person-years was 77 (95% confidence interval [CI] 62-96), compared with 9.3 (95% CI 4-23) for siblings. Treatment with CRT increased stroke risk in a dose-dependent manner: hazard ratio 5.9 (95% CI 3.5-9.9) for 30-49 Gy CRT and 11.0 (7.4-17.0) for 50+ Gy CRT. The cumulative stroke incidence in survivors treated with 50+ Gy CRT was 1.1% (95% CI 0.4-1.8%) at 10 years after diagnosis and 12% (95% CI 8.9-15.0%) at 30 years. Hypertension increased stroke hazard by 4-fold (95% CI 2.8-5.5) and in black survivors by 16-fold (95% CI 6.9-36.6). Conclusion: Young adult pediatric cancer survivors have an increased stroke risk that is associated with CRT in a dose-dependent manner. Atherosclerotic risk factors enhanced this risk and should be treated aggressively.

  16. Design of a family study among high-risk Caribbean Hispanics: the Northern Manhattan Family Study.

    Science.gov (United States)

    Sacco, Ralph L; Sabala, Edison A; Rundek, Tanja; Juo, Suh-Hang Hank; Huang, Jinaping Sam; DiTullio, Marco; Homma, Shunichi; Almonte, Katihurka; Lithgow, Carlos García; Boden-Albala, Bernadette

    2007-01-01

    Stroke continues to kill disproportionately more Blacks and Hispanics than Whites in the United States. Racial/ethnic variations in the incidence of stroke and prevalence of stroke risk factors are probably explained by both genetic and environmental influences. Family studies can help identify genetic predisposition to stroke and potential stroke precursors. Few studies have evaluated the heritability of these stroke risk factors among non-White populations, and none have focused on Caribbean Hispanic populations. The aim of the Northern Manhattan Family Study (NOMAFS) is to investigate the gene-environment interaction of stroke risk factors among Caribbean Hispanics. The unique recruitment and methodologic approaches used in this study are relevant to the design and conduct of genetic aggregation studies to investigate complex genetic disorders in non-White populations. The aim of this paper is to describe the NOMAFS and report enrollment and characteristics of the participants. The NOMAFS will provide a data resource for the exploration of the genetic determinants of highly heritable stroke precursor phenotypes that are less complex than the stroke phenotype. Understanding the gene environment interaction is the critical next step toward the development of new and unique approaches to disease prevention and interventions.

  17. Reducing the Risk of Spreadsheet Usage - a Case Study

    CERN Document Server

    Glass, Mel; Dewhurst, Sebastian

    2009-01-01

    The frequency with which spreadsheets are used and the associated risk is well known. Many tools and techniques have been developed which help reduce risks associate with creating and maintaining spreadsheet. However, little consideration has been given to reducing the risks of routine usage by the "consumers" - for example when entering and editing data. EASA's solution, available commercially, ensures that any routine process involving spreadsheets can be executed rapidly and without errors by the end-users, often with a significant reduction in manual effort. Specifically, the technology enables the rapid creation and deployment of web-based applications, connected to one or more centralized spreadsheets; this ensures version control, easy and error free usage, and security of intellectual property contained in spreadsheets.

  18. Risk Assessment of Vertical Breakwaters -- A Case Study in Turkey

    Institute of Scientific and Technical Information of China (English)

    Can Elmar BALAS; Levent KOC

    2002-01-01

    In the reliability-risk assessment, the second order reliability index (βⅡ) method and the Conditional ExpectationMonte Carlo (CEMC) simulation are interrelated as a new Level Ⅲ approach for the analysis of the safety level of theDalaman yacht harbor vertical wall breakwater in Turkey. The missing wave data of the Dalaman measurement station arehindcasted by use of muhi-layer feed-forward neural networks with the steepest descent and conjugate gradient algorithms.The structural failure probabilities of sliding and overturning failure modes are forecasted by approximation of the failure sur-face with a second-degree polynomial of an equal curvature at the design point. In the new approach, for each randomlygenerated load and tide combination, the joint failure probability reflects both the occurrence probability of loading conditionand the structural failure risk at the limit state. The approach can be applied to risk assessment of vertical breakwaters inshort CPU durations of portable computers.

  19. Risk perception among women receiving genetic counseling: a population-based follow-up study

    DEFF Research Database (Denmark)

    Mikkelsen, Ellen M; Sunde, Lone; Johansen, Christoffer;

    2007-01-01

    counseling, compared to a reduction of 5% (p=0.03) and 2% (p=0.01) in Reference Groups I and II, respectively. Risk communicated only in words, inaccurate risk perception at baseline, and presence of a familial mutation appeared to be predictors of inaccurate risk perception 12 months after counseling....... CONCLUSION: This population-based study of women with a family history of breast or ovarian cancer indicates that genetic counseling can help them both to reduce their perceived risk and to achieve a more realistic view of their risk of developing breast cancer. Udgivelsesdato: 2007-null......BACKGROUND: We aimed to explore the impact of genetic counseling on perceived personal lifetime risk of breast cancer, the accuracy of risk perception, and possible predictors of inaccurate risk perception 1 year following counseling. METHODS: We conducted a population-based prospective follow...

  20. Farmers' Perceived Risks of Climate Change and Influencing Factors: A Study in the Mekong Delta, Vietnam

    Science.gov (United States)

    Le Dang, Hoa; Li, Elton; Nuberg, Ian; Bruwer, Johan

    2014-08-01

    Many countries are confronting climate change that threatens agricultural production and farmers' lives. Farmers' perceived risks of climate change and factors influencing those perceived risks are critical to their adaptive behavior and well-planned adaptation strategies. However, there is limited understanding of these issues. In this paper, we attempt to quantitatively measure farmers' perceived risks of climate change and explore the influences of risk experience, information, belief in climate change, and trust in public adaptation to those perceived risks. Data are from structured interviews with 598 farmers in the Mekong Delta. The study shows that perceived risks to production, physical health, and income dimensions receive greater priority while farmers pay less attention to risks to happiness and social relationships. Experiences of the events that can be attributed to climate change increase farmers' perceived risks. Information variables can increase or decrease perceived risks, depending on the sources of information. Farmers who believe that climate change is actually happening and influencing their family's lives, perceive higher risks in most dimensions. Farmers who think that climate change is not their concern but the government's, perceive lower risks to physical health, finance, and production. As to trust in public adaptation, farmers who believe that public adaptive measures are well co-ordinated, perceive lower risks to production and psychology. Interestingly, those who believe that the disaster warning system is working well, perceive higher risks to finance, production, and social relationships. Further attention is suggested for the quality, timing, and channels of information about climate change and adaptation.

  1. Import risk analysis: A case study of white shrimp in Thailand

    Directory of Open Access Journals (Sweden)

    Supamattaya, K.

    2005-02-01

    Full Text Available As the culture industry of black tiger shrimp in Thailand has encountered several problems causing unsuccessful shrimp culture over decades, a new non-indigenous marine species, i.e. Pacific white shrimp (Penaeus vannamei was imported into Thailand as an alternation. However, imported white shrimp may carry some infectious agents which pose serious threats on aquatic species native to Thailand. Therefore, in the present study the import risk analysis (IRA was conducted to identify any hazard and estimate the risk presented by importation of white shrimp. The process involves the risk analysis steps of hazard identification and characterization, risk assessment and risk management. The risks associated with individual diseases and disease agents of white shrimp have been evaluated. Risk assessment conducted using risk evaluation matrix indicated high risk of Taura syndrome virus (TSV, White spot syndrome virus (WSSV and Infectious hypodermal and haematopoietic necrosis virus (IHHNV in imported white shrimp. The iterative process of risk management leads to a set of acceptable measures or strategies for each identified hazard for which the unrestricted risk is considered higher than appropriate level of protection. These measures or strategies will reduce risk to a level that is considered acceptable. Where measures or strategies that reduce the risk associated with a particular hazard to an acceptable level cannot be identified, permission to import the relevant commodity will be denied. The measures implemented in the control of white shrimp imports constitute quarantine and health certificate issued by exporting countries.

  2. Young Adult Exposure to Cardiovascular Risk Factors and Risk of Events Later in Life: The Framingham Offspring Study.

    Directory of Open Access Journals (Sweden)

    Mark J Pletcher

    Full Text Available It is unclear whether coronary heart disease (CHD risk factor exposure during early adulthood contributes to CHD risk later in life. Our objective was to analyze whether extent of early adult exposures to systolic and diastolic blood pressure (SBP, DBP and low-and high-density lipoprotein cholesterol (LDL, HDL are independent predictors of CHD events later in life.We used all available measurements of SBP, DBP, LDL, and HDL collected over 40 years in the Framingham Offspring Study to estimate risk factor trajectories, starting at age 20 years, for all participants. Average early adult (age 20-39 exposure to each risk factor was then estimated, and used to predict CHD events (myocardial infarction or CHD death after age 40, with adjustment for risk factor exposures later in life (age 40+. 4860 participants contributed an average of 6.3 risk factor measurements from in-person examinations and 24.5 years of follow-up after age 40, and 510 had a first CHD event. Early adult exposures to high SBP, DBP, LDL or low HDL were associated with 8- to 30-fold increases in later life CHD event rates, but were also strongly correlated with risk factor levels later in life. After adjustment for later life levels and other risk factors, early adult DBP and LDL remained strongly associated with later life risk. Compared with DBP≤70 mmHg, adjusted hazard ratios (HRs were 2.1 (95% confidence interval: 0.8-5.7 for DBP = 71-80, 2.6 (0.9-7.2 for DBP = 81-90, and 3.6 (1.2-11 for DBP>90 (p-trend = 0.019. Compared with LDL≤100 mg/dl, adjusted HRs were 1.5 (0.9-2.6 for LDL = 101-130, 2.2 (1.2-4.0 for LDL = 131-160, and 2.4 (1.2-4.7 for LDL>160 (p-trend = 0.009. While current levels of SBP and HDL were also associated with CHD events, we did not detect an independent association with early adult exposure to either of these risk factors.Using a mixed modeling approach to estimation of young adult exposures with trajectory analysis, we detected independent associations

  3. Mecanismos do ciclo sono-vigília Sleep-wake cycle mechanisms

    Directory of Open Access Journals (Sweden)

    Flávio Alóe

    2005-05-01

    Full Text Available Três sub-divisões hipotalâmicas são importantes no ciclo sono-vigília: o hipotálamo anterior (núcleos gabaérgicos e núcleos supraquiasmáticos, o hipotálamo posterior (núcleo túbero-mamilar histaminérgico e o hipotálamo lateral (sistema hipocretinas. O sistema gabaérgico inibitório do núcleo pré-óptico ventro-lateral (VLPO do hipotálamo anterior é responsável pelo início e manutenção do sono NREM. Os neurônios supraquiasmáticos (NSQs do hipotálamo anterior são responsáveis pelo ritmo circadiano do ciclo sono-vigília. Os núcleos aminérgicos, histaminérgicos, as hipocretinas e núcleos colinérgicos do prosencéfalo basal apresentam-se ativos durante a vigília, inibindo o núcleo pré-óptico ventro-lateral, promovendo a vigília. O processo de inibição-estimulação é a base do modelo da interação recíproca entre os grupos de células wake-off-sleep-on e células wake-off-sleep-on reguladores do ciclo sono-vigília. O modelo da interação recíproca também se aplica aos núcleos colinérgicos (células REM-on e aminérgicos (células REM-off do tronco cerebral no controle temporal do sono REM-NREM.Neurochemically distinct systems interact regulating sleep and wakefulness. Wakefulness is promoted by aminergic, acetylcholinergic brainstem and hypothalamic systems. Each of these arousal systems supports wakefulness and coordinated activity is required for alertness and EEG activation. Neurons in the pons and preoptic area control rapid eye movement and non-rapid eye movement sleep. Mutual inhibition between these wake- and sleep-regulating systems generate behavioral states. An up-to-date understanding of these systems should allow clinicians and researchers to better understand the effects of drugs, lesions, and neurologic disease on sleep and wakefulness.

  4. Ciclo do Marketing Digital: tática e estratégia Blended

    Directory of Open Access Journals (Sweden)

    Felipe Chibás Ortiz

    2013-07-01

    Full Text Available Este artigo discute sob o prisma relacional e processual a utilização da metodologia do Decálogo Digital, também conhecida como Ciclo do Marketing Digital elaborada pelo autor. No presente trabalho se justifica a necessidade de um sistema metodológico de trabalho prático e eficaz para a realização das campanhas de marketing que utilizam fundamentalmente os veículos disponíveis na Internet. Se fala das origens da pressente proposta fazendo um breve comparativo com os sistemas dos 4 Ps e os 8 Ps, Se apresentam algumas das diferenças das campanhas de marketing utilizando veículos presenciais e as que focam mais a utilização de mídias digitais,  se relacionam estes conteúdos com conceitos essenciais como os de estratégia, comunicação integrada, teoria dos inputs, throughputs e outputs, integração das mídias, marketing digital e responsável e gestão de redes virtuais. A seguir se define o Ciclo ou Decálogo do Marketing Digital e se explicam as etapas de trabalho com o sistema do Decálogo Digital responsável e se faz uma avaliação de suas possibilidades de aplicação na atualidade. Utilizou-se o método qualitativo, a revisão bibliográfica e o analise de documentos impressos e web, assim como as entrevistas em profundidade. O objetivo principal do presente trabalho é apresentar a proposta metodológica do Decálogo do Marketing Digital, também conhecida como Ciclo do Marketing Digital, mostrando as vantagens da utilização deste sistema de trabalho de caráter estratégico-operacional, para o profissional da comunicação.

  5. Relação entre Ciclo de Vida do Produto Turístico e Estratégias de Cooperação na Faixa Litorânea Urbana do Município de Natal

    Directory of Open Access Journals (Sweden)

    Anette Santiago Pereira

    2010-07-01

    Full Text Available Resumo Com a concretização das ações estruturantes para o turismo em Natal, se expandem as ações baseadas na cooperação e a formalização de instâncias de governança. Este estudo teve como objetivo analisar a relação entre o ciclo de vida do produto turístico ‘Litoral Urbano de Natal’ e as estratégias de cooperação em uma perspectiva histórica. A teoria está constituída de uma revisão sobre ciclo de vida, ecologia populacional, sistema de turismo, estratégias de cooperação e novas formas de gestão. Os resultados apontaram que o gráfico do ciclo de vida do produto ‘Litoral Urbano de Natal’, encontra-se migrando de uma fase de crescimento para uma fase de maturidade. As estratégias de cooperação identificadas foram o consórcio, estratégia coletiva e aglomerados, que se relacionam ao ciclo de vida do Produto Turístico através do alcance da eficiência coletiva. Palavras-chave: turismo; ciclo de vida do produto; cooperação. Abstract With the completion of tourism structuring actions, it was spread actions based on cooperation and formalization of governance institutions. This study aimed to examine the relationship between the tourism product life cycle 'Coastal Range of Natal” and the cooperation strategies in a historical perspective. The theoretical support is a revision about Resort Life Cycle, Theory of Population Ecology, System of Tourism, Co-operation Strategies and Management New Forms. Results showed that the life cycle graph of product 'Coastal Range of Natal’ is moving from one stage of growth to a stage of maturity. The co-operation strategies identified were consortium, collective strategy and clusters, which are related to the life cycle of the tourism product ‘Coastal Range of Natal’ when the efficiency of collective actions is achieved. Keywords: tourism; product life cycle; co-operation.

  6. [Risk of cancer among Danish electricity workers. A cohort study].

    Science.gov (United States)

    Johansen, C; Olsen, J H

    1999-04-05

    We report the incidence of cancer in a large cohort of employees identified from all 99 Danish utility companies. Personal data, and information on employment and exposure to magnetic fields and asbestos were obtained from manual files at the companies, the Danish Supplementary Pension Fund and the public payroll administration. A total of 32,006 individuals with more than three months of employment were linked with the files of the Danish Cancer Registry. Overall, 3008 cancers were observed, with 2825 expected, yielding a small but significantly increased risk of 1.06 (95% CI, 1.03-1.10). No excess was observed for all leukemias or for cancers of the brain or breast among men or women. There was no association of electromagnetic field exposure with risk of these cancers even when the level and length of exposure to magnetic fields were taken into account. Increased risks for cancers of the lung and pleural cavity were seen mainly for workers whose jobs involve exposure to asbestos. Our results do not support the hypothesis of an association between occupational exposures to magnetic fields in the electric utility industry and the risk for cancer.

  7. Risk indicators of anxiety throughout adolescence : The trails study

    NARCIS (Netherlands)

    van Oort, F. V. A.; Greaves-Lord, K.; Ormel, J.; Verhulst, F. C.; Huizink, A. C.

    2011-01-01

    Background: The aim was to identify risk indicators from preadolescence (age period 10-12) that significantly predict unfavorable deviations from normal anxiety development throughout adolescence (age period 10-17 years). Methods: Anxiety symptoms were assessed in a community sample of 2,220 boys an

  8. Risk indicators of anxiety throughout adolescence: the TRAILS study

    NARCIS (Netherlands)

    van Oort, F.V.A.; Greaves-Lord, K.; Ormel, J.; Verhulst, F.C.; Huizink, A.C.

    2011-01-01

    Background: The aim was to identify risk indicators from preadolescence (age period 10-12) that significantly predict unfavorable deviations from normal anxiety development throughout adolescence (age period 10-17 years). Methods: Anxiety symptoms were assessed in a community sample of 2,220 boys an

  9. Dietary mineral intake and lung cancer risk: the Rotterdam Study

    NARCIS (Netherlands)

    T. Muka (Taulant); B. Kraja (Bledar); R. Ruiter (Rikje); L. Lahousse (Lies); C.E. de Keyser (Catherina Elisabeth); A. Hofman (Albert); O.H. Franco (Oscar); G.G. Brusselle (Guy); B.H.Ch. Stricker (Bruno); J.C. Kiefte-de Jong (Jessica)

    2016-01-01

    textabstractObjective: Limited data are available on the role of mineral intake in the development of lung cancer (LC). We investigated whether dietary calcium, copper, iron, magnesium, selenium and zinc intake were associated with LC risk. Methods: We analyzed data from 5435 participants of the Rot

  10. Risk assessment for scented products: a pre-study

    NARCIS (Netherlands)

    Park MVDZ; Janssen PJCM; Raaij MTM van; SIR

    2007-01-01

    Little is known about the possible risks when consumers are exposed to fragrances. Fragrances are added to many consumer products, from detergents to toys. Passive room perfumes and spray perfumes represent two groups of products that are popular in use and may lead to high and long-lasting exposure

  11. Risk factors for Alzheimer's disease : a genetic-epidemiologic study

    NARCIS (Netherlands)

    C.M. van Duijn (Cock)

    1992-01-01

    textabstractThe work presented in this thesis has been motivated by the Jack of knowledge of risk factors for Alzheimer's disease. It has been long recognised that genetic factors are implicated, in particular in early-onset Alzheimer's disease.4 But to what extent are genetic factors involved? Are

  12. Economic evaluation studies of obstetric interventions in high risk pregnancies

    NARCIS (Netherlands)

    Vijgen, S.M.C.

    2013-01-01

    In this thesis we performed comparative costs and cost-effectiveness analyses for several clinical dilemmas in high risk pregnancies or deliveries, and explored practical and methodological issues in such research and to discuss the context of evidence-based policy making in relation to complex dile

  13. Ciclo político de los negocios y tamaño municipal: Colombia 1989-2008

    Directory of Open Access Journals (Sweden)

    Néstor Rubiano Páez

    2011-12-01

    Full Text Available Este ensayo realiza una prueba empírica de la hipótesis del "ciclo político de los negocios" en 547 municipios colombianos en el período 1989-2008. El trabajo econométrico indica que en los municipios de categoría 6 (los más pequeños y categoría 4, el gasto de inversión y el déficit fiscal exhiben tal ciclo: los gobernantes los amplían en época preelectoral y luego los contraen. Los resultados se sitúan en el contexto social colombiano para entender por qué el ciclo se presenta en esos municipios y coincide con baja eficiencia del gasto público en la lucha contra la pobreza medida según NBI. Recomienda algunas acciones de política para atenuar los efectos adversos del ciclo político y mejorar tal eficiencia.

  14. Obesity and Risk of Thyroid Cancer: Evidence from a Meta-Analysis of 21 Observational Studies

    Science.gov (United States)

    Ma, Jie; Huang, Min; Wang, Li; Ye, Wei; Tong, Yan; Wang, Hanmin

    2015-01-01

    Background Several studies have evaluated the association between obesity and thyroid cancer risk. However, the results remain uncertain. In this study, we conducted a meta-analysis to assess the association between obesity and thyroid cancer risk. Material/Methods Published literature from PubMed, EMBASE, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure (CNKI), and Chinese Biology Medicine (CBM) were retrieved before 10 August 2014. We included all studies that reported adjusted risk ratios (RRs), hazard ratios (HRs) or odds ratios (ORs), and 95% confidence intervals (CIs) of thyroid cancer risk. Results Thirty-two studies (n=12 620 676) were included in this meta-analysis. Obesity was associated with a significantly increased risk of thyroid cancer (adjusted RR=1.33; 95% CI, 1.24–1.42; I2=25%). In the subgroup analysis by study type, increased risk of thyroid cancer was found in cohort studies and case-control studies. In subgroup analysis by sex, both obese men and women were at significantly greater risk of thyroid cancer than non-obese subjects. When stratified by ethnicity, significantly elevated risk was observed in Caucasians and in Asians. In the age subgroup analysis, both young and old populations showed increased thyroid cancer risk. Subgroup analysis on smoking status showed that increased thyroid cancer risks were found in smokers and in non-smokers. In the histology subgroup analyses, increased risks of papillary thyroid cancer, follicular thyroid cancer, and anaplastic thyroid cancer were observed. However, obesity was associated with decreased risk of medullary thyroid cancer. Conclusions Our results indicate that obesity is associated with an increased thyroid cancer risk, except medullary thyroid cancer. PMID:25612155

  15. Alcohol and ovarian cancer risk: Results from the Netherlands Cohort Study

    NARCIS (Netherlands)

    Schouten, L.J.; Zeegers, M.P.A.; Goldbohm, R.A.; Brandt, P.A. van den

    2004-01-01

    Objective: To study alcohol consumption in relation to ovarian cancer risk in a prospective cohort study. Methods: The Netherlands Cohort Study on diet and cancer was initiated in 1986. A self-administered questionnaire on dietary habits and other risk factors for cancer was completed by 62,573 post

  16. ¿Sincronizaron México y Estados Unidos sus ciclos económicos con el TLCAN?

    Directory of Open Access Journals (Sweden)

    Domingo Rodríguez Benavides

    2015-01-01

    Full Text Available En este trabajo investigamos, a través de un modelo estructural de series de tiempo múltiple, con una especificación generalizada de ciclo estocástico, si los ciclos económicos del PIB de México muestran una mayor sincronización con los ciclos del PIB de Estados Unidos a partir de la entrada en vigor del Tratado de Libre Comercio de América del Norte (TLCAN, con respecto al periodo previo. Con tal fin, probamos la hipótesis nula de un ci - clo común, como es definida en los modelos estructurales como el empleado por Carvalho, Harvey y Trimbur (2007, contra la hipótesis de un ciclo similar entre ambas economías. La existencia de un ciclo económico común entre dos economías implica que uno de ellos es proporcional al otro (Harvey 2002. Los resultados muestran que antes de la entrada en vigor del TLCAN (1960:1-1994:4 ninguna de las dos economías posee un ciclo econó - mico común. Al contrario, a partir de la firma del TLCAN (1995:1-2012:4, no es posible rechazar la hipótesis de la existencia de un ciclo económico común entre ambas economías, lo cual interpretamos como una mayor sincronización de sus productos. Observamos, sin embargo que, con respecto al periodo previo, la sincronización cíclica ocurre en un periodo de lento crecimiento donde los flujos comerciales del TLCAN con Estados Unidos decli - nan relativamente desde el año 2000. Ello cuestiona el fundamento de la sincronización, explicada en México por la apertura comercial del TLCAN. Derechos Reservados©2015 Universidad Nacional Autónoma de México, Facultad de Contaduría y Administración. Este es un artículo de acceso abierto distribuido bajo los términos de la Licencia Creative Commons CC BY-NC-ND 4.0.

  17. Dairy Supply Chain Risk Management in Bangladesh: Field studies of Factors and Variables

    Directory of Open Access Journals (Sweden)

    Tasnuba Nasir

    2014-01-01

    Full Text Available Supply chain risk management (SCRM has gained wide attention among the academia and the business community in the present competitive business world. This paper aims to investigate the main risk factors associated with the dairy industry along with focuses on possible mitigation strategy to mitigate those risks. Qualitative field study has been undertaken in this research. The results of the interviews identify the different risk issues along with the possible mitigation strategies, embedded at storage, processing and distribution level in dairy industry of Bangladesh. The practical implication will contribute significantly to the dairy sector in terms of mitigating risks.

  18. The credibility of risk information about licit substances: An exploratory study of attitudes among Swedish adults

    Directory of Open Access Journals (Sweden)

    Ekendahl Mats

    2015-09-01

    Full Text Available AIMS – Providing risk information on licit substances is a central health promotion strategy. There is, however, very little knowledge about public attitudes on this information. In this exploratory study we analyse the extent to which Swedish adults: 1 trust risk information regarding alcohol, cigarettes and wet snuff (“snus” provided by public authorities, 2 perceive risk information regarding alcohol, cigarettes and snus as consistent, and 3 have received an adequate amount of risk information from public authorities regarding these substances. The aim is also to investigate if certain characteristics among participants are related to their perceptions of such risk information.

  19. Multimodal evoked potentials and the ovarian cycle in young ovulating women Potenciais evocados nas diferentes fases do ciclo menstrual da mulher

    Directory of Open Access Journals (Sweden)

    LUIZ ANTONIO DE LIMA RESENDE

    2000-06-01

    Full Text Available There is controversy over how hormonal conditions influence cerebral physiology. We studied pattern-shift visual evoked potentials (PS-VEP, brain stem auditory evoked potentials (BAEP and short-latency somatosensory evoked potentials (SSEV in 20 female volunteers at different phases of the menstrual cycle (estrogen phase, ovulatory day and progesterone phase. Statistical analysis showed decreased latencies for P100 (PS-VEP, N19 and P22 (SSEV waves in the progesterone phase compared with the estrogen phase. There was no significant difference between the estrogen and the ovulation day values. Comparing the three above stages, there were no significant differences in the brainstem auditory evoked potentials. The reduction of the latencies of the potentials generated in multisynaptic circuits provides the first consistent neurophysiological basis for a tentative comprehension of human pre-menstrual syndrome.Há controvérsias sobre como variações hormonais do ciclo menstrual da mulher influenciam a neurofisiologia cerebral. Estudamos potenciais evocados de curta latência, visuais, auditivos e sômato-sensoriais, em 20 mulheres voluntárias normais, nas diferentes fases do ciclo menstrual (fase estrogênica, fase ovulatória, fase progestacional. Comparação entre fase estrogênica e ovulatória mostrou resultados similares. Ondas I, III, V dos potenciais evocados auditivos não apresentaram diferenças estatisticamente significativas entre as três fases do ciclo. Análise estatística dos resultados mostrou diminuição significativa das latências das ondas P100, N19 e P22 obtidas na fase progestacional, comparadas com aquelas obtidas na fase estrogênica. Como estas ondas são geradas em circuitos multissinápticos, tal redução de latências, na fase progestacional, fornece a primeira base neurofisiológica consistente para tentativa de compreensão da síndrome pré-menstrual da mulher.

  20. Custo de ciclo econômico no Brasil em um modelo com restrição a crédito

    Directory of Open Access Journals (Sweden)

    Bárbara Vasconcelos Boa Vista da Cunha

    2004-06-01

    Full Text Available O estudo do impacto de ciclo econômico no bem-estar dos indivíduos de uma economia é um assunto de grande importância teórica. Ao considerarmos a economia brasileira, em que grande maioria dos indivíduos não dispõe de mecanismos de crédito, ele torna-se ainda mais relevante. Se os agentes não são capazes de suavizar consumo segundo a hipótese da renda permanente de Friedman, é de se esperar que estes sofram impactos ainda maiores diante de flutuações na renda. Utilizamos o modelo proposto por Imrohoroglu (1989 para os dados da economia brasileira a fim de mensurar a perda de bem-estar causada por um ciclo econômico. A partir de resultados que mostram o significativo custo dos ciclos econômicos, propomos a introdução do governo no modelo. Agindo no sentido de completar mercados, o governo se mostrou eficiente. Apesar de simples, nosso experimento mostrou a importância de investigarmos a ação governamental como opção para a elevação do bem-estar em economias restritas ao crédito ao longo de flutuações econômicas.This article studies the welfare cost of business cycles fluctuation in Brazil. We use a model, due to Imrohoroglu (1989, in which agents are ex-post heterogeneous with respect to employment and cannot smooth perfectly consumption as they are credit restricted. This is highly relevant as the evidence is that at least 75% of Brazilian population has no access to credit markets so that their consumption path tend to be highly sensitive to economic variability. Our simulations show that in fact welfare losses due to output fluctuations are significant in Brazil and much higher than the losses found for the US economy. We introduce in the model public policies that tend to complete markets and act as an (imperfect insurance. With a very simple tax and transfer mechanism we show that the government can increase considerably welfare.

  1. Beverage preference and risk of alcohol-use disorders: a Danish prospective cohort study

    DEFF Research Database (Denmark)

    Flensborg-Madsen, Trine; Knop, Joachim; Mortensen, Erik Lykke;

    2008-01-01

    OBJECTIVE: The purpose of this study was to examine whether preferred type of alcoholic beverage influences the later risk of alcohol-use disorders (AUD). METHOD: A prospective cohort study was used, comprising three updated measures of alcohol intake and covariates, and 26 years of follow-up data...... had a risk of 3.1 (CI: 1.8-5.4), whereas those whose total alcohol intake comprised more than 35% wine had a risk of 0.8 (CI: 0.3-2.1). Consuming more than 35% beer increased the risk of AUD for women, whereas the percentage of distilled spirits intake did not influence the risk of AUD for either...... on 18,146 individuals from the Copenhagen City Heart Study, Denmark. The study population was linked to three different registers to detect AUD registrations. RESULTS: For both genders, wine drinking was associated with lower risk of AUD irrespective of the weekly amount of alcohol consumed. Women...

  2. Los ciclos económicos departamentales en Colombia, 1960-2011

    Directory of Open Access Journals (Sweden)

    Fredy Vásquez Bedoya

    2014-06-01

    Full Text Available En este trabajo se estima el ciclo del PIB nacional y de algunos departamentos entre 1960 y 2011 usando el modelo de tendencia lineal local de Nelson y Plosser, así como el coeficiente de correlación entre el componente cíclico de las series del PIB departamental y nacional para clasificar sus co-movimientos. El estudio revela una diversidad de comportamientos de las fluctuaciones económicas departamentales con respecto a la nacional y, además, que las economías departamentales fuertemente procíclicas son las más diversificadas y más ricas.

  3. Efecto in vitro de olomoucina en el ciclo celular de linfocitos humanos

    Directory of Open Access Journals (Sweden)

    Camargo M.

    2001-06-01

    Full Text Available La olomoucina, un derivado de purina relacionado con el ATP, ha sido reportado como uneficiente inhibidor del ciclo celular de células animales y vegetales, debido a su alta especificidadpor las ciclinas dependientes de kinasa (CDK CDK1 y CDK2, su capacidad radica en inhibir elciclo celular en las transiciones G2/M y G1/S respectivamente. Con el objetivo de explorar lapotencial aplicación de la olomoucina en el análisis citogenético de alta resolución y estudiosde proliferación celular en cultivos primarios, linfocitos humanos fueron cultivados en RPMI1640 suplementado con suero bovino fetal al 5%, estimuladas durante 72 horas con PHA yposteriormente tratadas con concentraciones de 50, 100 y 200 mM durante 12 y 24 horas.

  4. Ciclo vigília/sono em portadores de diabetes mellitus tipo 1.

    OpenAIRE

    Mark Thomaz Ugliara Barone

    2011-01-01

    O objetivo do presente estudo foi avaliar possíveis relações entre o diabetes mellitus tipo 1 (DM1) e controle glicêmico, e o ciclo vigília/sono. Participaram 18 voluntários com DM1 (idade: 26,3±5,1), sem complicações, não obesos, sem alterações no sono; e 9 no grupo controle (idade: 28,8±5,3). Os dados foram coletados através de: diário de sono e de glicemia, actímetria (Tempatilumi), polissonografia, 6-sulfatoximelatonina, questionário de Epworth, e sensor de glicose durante a polissonograf...

  5. Un panorama sobre la fase recesiva del ciclo económico

    Directory of Open Access Journals (Sweden)

    Alejandro D. Jacobo

    2012-04-01

    Full Text Available Resumen:Este trabajo proporciona una introducción a las recesiones económicas. Con fines didácticos, se revisa y ensambla una serie de conceptos, realizando todo el esfuerzo para presentar el trabajo de manera amigable hacia quienes poseen un disgusto natural hacia esta fase poco placentera del ciclo económico.  Abstract:This paper provides an introduction for understanding the economic recessions. With didactical purposes, a bunch of concepts are revised and linked, and every effort is made to write the paper amiable for those one who have a natural dislike for this unpleasant phase of the business cycle. 

  6. La sostenibilidad en la arquitectura industrializada: cerrando el ciclo de los materiales

    Directory of Open Access Journals (Sweden)

    Wadel, G.

    2010-03-01

    Full Text Available The condition of sustainability, from a physical point of view, can be defined as the closure of the material cycle. This is reached in determined systems, in the absence of residual flows, and in which resources are constantly recycled. Such systems can encounter serious obstacles in the productive model that characterises the majority of contemporary industry. The productive model, born during the Industrial Revolution, can be summarised by the following lineal sequence: extraction > manufacture > use > residue. In contrast, this research focuses on a productive model from the ecological industry, based on the example of the biosphere as a recycling machine. Requiring the elimination of the concept of residues, the system can be summarised by the following continuous cycle: recycling-manufacturing-use-recycling. The hypothesis posed is as follows: using technology presently available, represented by the lightweight modular construction that is commercialised by renting (making it possible to return the modules to the factory once their useful life is over, therefore recuperating resources, a management system capable to close the material cycle at least to 90% can be developed. (conventional building construction currently manages a recycling value of 10% of used resources.

    La condición de sostenibilidad, desde el punto de vista físico, puede ser definida como el cierre de los ciclos materiales, alcanzándose éste en un sistema determinado cuando no existen flujos de residuos sino que los recursos se reciclan constantemente. Tal condición encuentra un fuerte obstáculo en el modelo productivo que caracteriza a la mayor parte de la industria contemporánea, nacido en la revolución industrial, que puede sintetizarse en la secuencia lineal extracción > fabricación > uso > residuo. En oposición a ello, el modelo productivo en el que se centra la investigación que aquí se presenta es la ecología industrial y se basa en el

  7. Perfil dos Professores Municipais do Ensino Fundamental de Presidente Prudente (Ciclo I

    Directory of Open Access Journals (Sweden)

    Yoshie Ussami Ferrari Leite

    2009-12-01

    Full Text Available Neste artigo, apresentamos o resultado de levantamento, realizado junto aos professores do Ciclo I do Ensino Fundamental do Sistema Municipal de Presidente Prudente, Estado de São Paulo. O estudo teve por finalidade identificar o perfil dos docentes que atuam nas séries iniciais do Ensino Fundamental, suas representações, dificuldades e expectativas, tendo em vista, posteriormente, a propositura de uma política de desenvolvimento profissional desses professores. Cuidar do desenvolvimento profissional dos professores, mediante formação continuada centrada na unidade escolar, é condição imprescindível para que, hoje em dia, o professor possa desempenhar a docência de forma mais qualificada, atendendo às exigências do mundo contemporâneo.

  8. EFECTOS DEL CICLO ECONOMICO EN EL CREDITO COMERCIAL: EL CASO DE LA PYME ESPANOLA

    Directory of Open Access Journals (Sweden)

    Canto-Cuevas, Francisco-Javier

    2016-05-01

    Full Text Available Este trabajo estudia los efectos de la situacion economica sobre el credito comercial en las pequenas y medianas empresas. Para lograr este objetivo, se analiza una muestra de pymes espanolas durante los anos 2004 a 2011, periodo que incluye una etapa de expansion y otra de recesion, utilizando la metodologia de datos de panel. Los resultados muestran que el ciclo economico afecta de manera significativa al credito comercial recibido y concedido, produciendose un aumento en la etapa de bonanza economica y una contraccion durante la crisis. Ademas son las empresas mas vulnerables financieramente las que durante la crisis, por un lado, tienen mas dificultades para conseguir financiacion via credito comercial, pero al mismo tiempo mas incrementan su credto a clientes. Por ultimo, aquellas firmas con mayor capacidad de generar recursos conceden mas credito a sus clientes.

  9. El movimiento estudiantil catalán en el nuevo ciclo de luchas

    OpenAIRE

    González García, Robert; Benítez Romero, Isabel

    2014-01-01

    Objetivo: analizar la evolución del movimiento estudiantil catalán en los últimos 20 años (1993-2013) para comprender los contextos de implantación de modelos neoliberales de gestión de la universidad y de ciclos de movilización a los que responden las diversas etapas del movimiento.Metodología: a partir de la hermenéutica de procesos sociales y a través del análisis de documentación emitida por el movimiento estudiantil catalán y de un ejercicio de reflexión conjunta de los autores con base ...

  10. Ciclo biológico de Triatoma rubrovaria (Blanchard (Reduviidae, Triatominae en laboratorio

    Directory of Open Access Journals (Sweden)

    Nilda V. de Argüello

    1988-01-01

    Full Text Available Fez-se uma avaliação estatística do ciclo de vida de Triatoma rubrovaria, com base em experimentos de laboratório. Foram computados a eclosão do ovo, o tempo de desenvolvimento da ninfa e sua mortalidade, e a longevidade dos adultos, machos e fêmeas; os resultados foram comparados com os da literatura existente.A statistical evaluation of the life cycle of Triatoma rubrovaria is based on cohort experiments conducted under controlled laboratory conditions. Egg hatching, nymphal development time and mortality, adult male and femals longevity were computed, and the results compared with information in the existing literature.

  11. Assessing Landscape Ecological Risk in a Mining City: A Case Study in Liaoyuan City, China

    Directory of Open Access Journals (Sweden)

    Jian Peng

    2015-06-01

    Full Text Available Landscape ecological risk assessment can effectively identify key elements for landscape sustainability, which directly improves human wellbeing. However, previous research has tended to apply risk probability, measured by overlaying landscape metrics to evaluate risk, generally lacking a quantitative assessment of loss and uncertainty of risk. This study, taking Liaoyuan City as a case area, explores landscape ecological risk assessment associated with mining cities, based on probability of risk and potential ecological loss. The assessment results show landscape ecological risk is lower in highly urbanized areas than those rural areas, suggesting that not only cities but also natural and semi-natural areas contribute to overall landscape-scale ecological risk. Our comparison of potential ecological risk in 58 watersheds in the region shows that ecological loss are moderate or high in the 10 high-risk watersheds. The 35 moderate-risk watersheds contain a large proportion of farmland, and the 13 low-risk watersheds are mainly distributed in flat terrain areas. Our uncertainty analyses result in a close range between simulated and calculated values, suggesting that our model is generally applicable. Our analysis has good potential in the fields of resource development, landscape planning and ecological restoration, and provides a quantitative method for achieving landscape sustainability in a mining city.

  12. A Study of Risk Factors and T- Score Variability in Romanian Women with Postmenopausal Osteoporosis.

    Directory of Open Access Journals (Sweden)

    Rodica TöRöK-Oance

    2013-12-01

    Full Text Available The purpose of this study was to analyse the prevalence of postmenopausal osteoporosis risk factors and to analyse the T-score variability in spine and hip according to the associated risk factors.This is a retrospective study (2003-2007 including 177 female patients with postmenopausal osteoporosis. The patients were separated in seven groups according to the number of risk factors per case. The T-score was compared between this groups using unpaired t-Student test.The most frequent risk factor was early menopause (44.63%, followed by low consumption of dairy products (37.29%, coffee consumption (25.99%, sedentary lifestyle (20.9%, smoking (19.21%, delayed menarche (15.25%, low body mass index (10.71%, nulliparity (7.91%, alcohol consumption (0.56%. The maximum number of risk factors per case was six. The T-score decreased with increasing number of risk factors. T-score differences are statistically significant when comparing cases with 6 risk factors to cases with 5 risk factors (P=0.0315 in spine; P=0.0088 in hip, 4 risk factors (P=0.0076 in spine; P=0.043 in hip, 3 risk factors (P<0.0001 in spine; P=0.0205 in hip, 2 risk factors (P=0.0012 in spine; P<0.0001 in hip, a single risk factor (P<0.001 in spine and hip and no risk factor (P=0.0075 in spine; P=0.0006 in hip.Association of several risk factors leads to decrease of T-score so being able to avoid any such factors may contribute to a better bone mineral density. This could be achieved by the education of female population regarding postmenopausal osteoporosis risk factors, followed by adopting an appropriate lifestyle and diet.

  13. Ciclos y determinantes del crecimiento económico: Perú 1950-1996

    Directory of Open Access Journals (Sweden)

    Félix Jiménez

    1997-12-01

    Full Text Available En este ensayo se analiza el crecimiento económico y sus fluctuacionesdurante el período 1950-1995, así como el estancamiento prolongado queempieza en los años 1975-1978, apoyados en la hipótesis de que la dinámicade este crecimiento obedece al carácter desequilibrado del proceso de industrializacióny a un comportamiento de la inversión que no estuvo sujeta alproceso sustitutivo. Con un vector de inversiones que no estimula el mercadodoméstico, el crecimiento y los ciclos son determinados por impulsos dedemanda que provienen del sector público y/o de aquellos mercados externosdonde la producción manufacturera doméstica resulta competitiva. Como elaumento de la demanda repercute en un mayor déficit externo, ei crecimientosostenido a largo plazo resulta imposible si no se resuelven los problemasestructurales del sector manufacturero. Una vez corroborada la importancia deeste sector y dadas sus correlaciones significativas con los otros sectoresdeterminados por demanda, se construye una serie de producción no primaria,para luego explicar su comportamiento en el largo plazo, sometiendo a pruebala importancia del gasto del Estado en la generación de los ciclos y tendenciadel producto, utilizando la metodología de la cointegración. Por último, seestima el valor del producto potencial no-primario que permite corroborar lahipótesis del largo estancamiento en el período de agotamiento del procesosustitutivo.

  14. AMONIO-OXIDASAS BACTERIANAS Y ARQUEALES INVOLUCRADAS EN EL CICLO DEL NITRÓGENO

    Directory of Open Access Journals (Sweden)

    Sergio Andrade Ochoa

    2015-09-01

    Full Text Available La nitrificación, la oxidación microbiana de amoníaco a nitrato, juega un papel crítico en el ciclo global del nitrógeno. Se ha considerado a dos grupos distintos de bacterias capaces de oxidar el amoníaco (AOB como las responsables de llevar a cabo el primer paso de la nitrificación; en esos dos grupos se encuentran las Beta-proteobacterias, que incluyen a los géneros Nitrosomonas y Nitrosospira, y las Gamma-proteobacterias, que engloban al género Nitrosococcus. Sin embargo, se ha demostrado la existencia de arqueas oxidantes de amoníaco (AOA y su contribución al ciclo del nitrógeno, siendo Nitrosopumilus maritimus la más estudiada en este proceso. La dinámica entre estos dos sistemas de oxidantes de amoníaco es compleja y los estudios se han enfocado a distintos hábitats, se ha propuesto que las contribuciones relativas de las comunidades AOA y AOB dependen de propiedades fisicoquímicas del ambiente, que afectan su abundancia y diversidad; esto dificulta establecer con exactitud el nicho ecológico en el que se desempeña cada comunidad. El objetivo de esta revisión es discutir la evidencia científica que facilite el entendimiento del papel que desempeñan los microorganismos oxidantes del amoníaco.

  15. Tipos de hogar, ciclo de vida familiar y pobreza en Costa Rica 1987-2002

    Directory of Open Access Journals (Sweden)

    Barquero, Jorge

    2004-07-01

    Full Text Available El propósito de este estudio fue el de explorar las condiciones vulnerabilidad sociodemográfica en Costa Rica, a partir del análisis de los cambios en los tipos de hogar y el ciclo de vida de las familias en condiciones de pobreza, utilizando información de las Encuestas de Hogares de 1987, 1994 y 2002. Los principales hallazgos revelan modificaciones importantes en la estructura y composición de los hogares y familias en el periodo de estudio, asociado a cambios en la dinámica sociodemográfica de la sociedad costarricense. La evolución en la incidencia de la pobreza por tipo de hogar muestra que ésta es mayor entre los hogares nucleares que cuentan con hijos y al convertirse en monoparentales. La incidencia es más alta en 1987, se reduce para 1994 y prácticamente se mantiene para el 2002. No obstante que en todas las fases del ciclo de vida familiar la incidencia de la pobreza disminuyó en el periodo 1987-1994, en el periodo más reciente al 2002 la incidencia es mayor en las etapas en que las familias poseen más hijos dependientes menores de 18 años, lo que expone a estas familias a una mayor vulnerabilidad a situaciones de pobreza. Los hogares y familias con mayor riesgo de vulnerabilidad ante la pobreza, se hallaron entre aquellos con mayor cantidad de miembros dependientes menores de edad y jefeados por mujeres. No se encontraron evidencias significativas para afirmar que el estancamiento observado en los niveles de pobreza en el país hasta el 2002, fuese producto de los cambios encontrados en los patrones familiares, aunque ciertamente se hace necesario profundizar el análisis de las interrelaciones entre pobreza y cambios demográficos.

  16. Os ciclos escolares: elementos de uma trajetória School cycles: elements of a trajectory

    Directory of Open Access Journals (Sweden)

    Elba Siqueira de Sá Barretto

    1999-11-01

    Full Text Available Este artigo se propõe a evidenciar algumas características presentes em muitos dos ensaios de implantação dos ciclos escolares no país, bem como as justificativas para a sua adoção. Assim o faz por entender que o domínio das representações e da cultura, bem como o das fundamentações teóricas e das razões políticas que compõem as justificativas é um dos mais significativos na constituição das múltiplas determinações das reformas educacionais. São revisitados alguns textos antológicos da História da Educação Brasileira que situam a discussão em décadas passadas, bem como registradas iniciativas de adoção dos ciclos em diferentes períodos e em espaços diversos, recuperando-se inclusive dados de pesquisa sobre as propostas curriculares dos estados e de alguns municípios, vigentes entre 1985 e 1995.This article proposes to show some of the characteristics present in many of the attempts to implant school cycles in the country, as well as the justification for their adoption. It states that dominion of representation of culture, as well as of the theoretical fundamentals and political logic that comprise the justifications are the most significant points among the multiple determinants of educational reform. Some basic texts in the history of Brazilian education, which locate the discussion in the past decades, are reviewed along with recorded initiatives in adopting the cycles during different periods and in diverse locations. Data from research on curriculum proposals in some of the states and cities, in effect between 1985 and 1995 is reviewed and recovered.

  17. Study on institutionalization of risk-informed performance-based regulation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, M. G.; Hong, S. Y.; Seo, M. R. [Korea Electric Power Research Institute, Taejon (Korea, Republic of)

    2003-02-15

    In this study, for the institutionalization of risk informed and performance based regulation in Korea, the latest technical movements of overseas countries are examined and reviewed. And the issues that was found when license change petition using risk information was submitted in Korean regulatory body are reviewed. Based on these review, the applicable areas to domestic situation will be found and proposed. This study can contribute to setting up the proper direction for the institutionalization of risk informed and performance based regulation.

  18. Risk Determination, Prioritization, and Classifying in Construction Project Case Study: Gharb Tehran Commercial-Administrative Complex

    Directory of Open Access Journals (Sweden)

    Azadeh Sohrabinejad

    2015-01-01

    Full Text Available Construction projects play an important role in infrastructure projects in developing countries. According to type, size, and complexity of the project, the number and importance of each risk could be different and many projects cannot reach the project goals due to exposure to multiple risks. Many papers have been published on the subject of risk management in construction projects; unfortunately most of them have not been implemented in practical conditions. The aim of this study is to identify and prioritize risks in construction projects. The classical approach used probability and impact for risk assessment, but these criteria do not sufficiently address all aspects of projects risks and there might be a relationship between different criteria. This study proposes the hierarchical dependencies between criteria. A case study of construction project is presented to illustrate performance and usage of the proposed model. Utilizing library studies and interview with experts, managers, and specialists, decision criteria were identified through brain storming. Risks were categorized by the experts into eleven risks. Important risks were evaluated based on the fuzzy ANP, fuzzy DEMATEL, and fuzzy TOPSIS methods. The proposed model is more suitable than the traditional decision-making methods in prioritizing risk concerning cost, time, and quality.

  19. [Serological studies of early summer meningoencephalitis risk in the Saarland].

    Science.gov (United States)

    Müller, K D; Ansorg, R

    1987-04-01

    To evaluate the risk of acquiring TBE in the Saarland, tick-borne encephalitis (TBE) antibodies were investigated in the sera of 408 persons working in forestry, 44 patients with suspected viral infection of the central nervous system, and of 439 animals which had been particularly exposed to ticks. A complement fixation test was used for all sera. The human sera were additionally tested with an enzyme-linked immunosorbent assay. TBE antibodies were found in eight forestry employees who had been vaccinated against TBE. All other persons as well as the animals did not show TBE antibodies. The very low antibody rate in the risk groups indicates that the Saarland is free of natural foci of TBE. At present, there is no argument for a general TBE immunprophylaxis in that area.

  20. Ciclo diário e semidiário de precipitação na costa norte do Brasil Diurnal and semidiurnal rainfall cycle over north coastland of Brazil

    Directory of Open Access Journals (Sweden)

    Cláudio Moisés Santos Silva

    2013-03-01

    Full Text Available Estudou-se o ciclo diário e o ciclo semidiário da precipitação na região costeira do Norte do Brasil. Usou-se 13 anos de dados ininterruptos de precipitação estimados através do algoritmo 3B42_V6 do projeto TRMM. Os ciclos foram analisados por quadrimestres. Para obter informações sobre amplitude, fase e fração de variância de cada ciclo, utilizou-se a análise harmônica do ciclo composto no período de 24 horas para cada quadrimestre. Regiões mais próximas da costa apresentaram ciclos modulados por mecanismos oceânicos e, portanto, tendem a apresentar o máximo de precipitação no início da manhã e a noite. Regiões mais afastadas da costa apresentaram máximos às 2100 UTC (17:00 HL em função dos mecanismos de convecção local. A região Nordeste do Pará apresentou as maiores amplitudes de precipitação. Durante o quadrimestre de janeiro a abril observou-se as maiores taxas de precipitação. Não há variações sazonais significativas na fase dos ciclos. Os dois harmônicos correspondem a cerca de 80% do total da variância diária dos dados. No final, algumas sugestões de trabalhos futuros e aplicabilidade dos dados do 3B42_V6 são discutidas.The diurnal and semidiurnal rainfall cycles observed over the Brazilian North coastland were studied. A 13 years rainfall dataset derived by the 3B42_V6 algorithm was used. To obtain the amplitude, phase, and variance of each cycle the harmonic analysis was applied to the mean rainfall of 24 hours. Coastlands areas showed cycles modulated by oceanic mechanisms, thus the maximum rainfall was observed at early-morning and nighttime. Inland regions exhibited maximum rainfall at 2100 UTC (17:00 LST due the local convection mechanism. The highest amplitude of precipitation was observed over the Northeast of the Pará State. The highest rainfall rates were observed during January to April period. The phase of each cycle do not presented significant seasonal variation. The diurnal

  1. A study of risk factors for preterm labour

    Directory of Open Access Journals (Sweden)

    Shannon F. Fernandes

    2015-10-01

    Conclusions: If we take into account the increase in multiple pregnancies and induced preterm birth, spontaneous preterm birth in singleton pregnancies has probably decreased. This decrease in preterm birth is undoubtedly related to better prenatal care for all pregnant women. The recognition of risk factors for preterm labour constitutes a part of basic prenatal care. Most etiological factors are modifiable, and preconception counselling should emphasize and address these issues. [Int J Reprod Contracept Obstet Gynecol 2015; 4(5.000: 1306-1312

  2. La fortuna del ciclo de "Daniel en el foso de los leones" en los programas escultóricos románicos de Galicia

    Directory of Open Access Journals (Sweden)

    Moure Pena, Teresa C.

    2006-09-01

    Full Text Available This study is focused on the iconographic cycle of Daniel in the Lions Den within the sculptural programs of the Galician Romanesque. Analysis of the representations allows for the proposal of a series of theories concerning the connection between figuration and context, and particularly the value and signification acquired by the theme in the monastic milieu.

    El objetivo de este artículo se centra en el estudio del ciclo iconográfico de Daniel en el foso de los leones en los programas figurativos del románico gallego. El análisis de las representaciones nos permitirá proponer una serie de teorías sobre la conexión entre figuración y el contexto en el que se dispone y, especialmente el valor y significado que el tema adquiere en el ámbito monástico.

  3. Ciclo evolutivo do Hepatozoon triatomae (Sporozoa, Haemogregarinidae parasita de triatomíneos Evolution cycle of the Hepatozoon triatomae (Sporozoa, Haemogregarinidae, parasite of triatominea

    Directory of Open Access Journals (Sweden)

    Eduardo Olavo da Rocha e Silva

    1975-09-01

    Full Text Available Relata-se o encontro no Estado de São Paulo, Brasil, de triatomíneos e lagartos, respectivamente o Triatoma arthurneivai e Tropidurus torquatus, parasitados por uma hemogregarina semelhante a Hepatozoon triatomae (Osimani, 1942 Reichenow, 1953. São apresentados aspectos da sua morfologia e estudadas as diversas fases do seu ciclo evolutivo, este inteiramente reproduzido em laboratório.The author relates the discovery of Triatoma arthurneivai and Tropidurus torquatus, in the localities of Lavras de Cima and Santo Antonio, State of São Paulo, Brazil, infected by a hemogregarine similar to Hepatozoon triatomae (Osimani, 1942 Reichenow 1953. He presents certain aspects of its morphology and also studies the several phases of its evolution cycle, which were completed in the laboratory.

  4. Risk factors for venous thromboembolism in women under combined oral contraceptive. The PILl Genetic RIsk Monitoring (PILGRIM) Study.

    Science.gov (United States)

    Suchon, Pierre; Al Frouh, Fadi; Henneuse, Agathe; Ibrahim, Manal; Brunet, Dominique; Barthet, Marie-Christine; Aillaud, Marie-Françoise; Venton, Geoffroy; Alessi, Marie-Christine; Trégouët, David-Alexandre; Morange, Pierre-Emmanuel

    2016-01-01

    Identifying women at risk of venous thromboembolism (VTE) is a major public health issue. The objective of this study was to identify environmental and genetic determinants of VTE risk in a large sample of women under combined oral contraceptives (COC). A total of 968 women who had had one event of VTE during COC use were compared to 874 women under COC but with no personal history of VTE. Clinical data were collected and a systematic thrombophilia screening was performed together with ABO blood group assessment. After adjusting for age, family history, and type and duration of COC use, main environmental determinants of VTE were smoking (odds ratio [OR] =1.65, 95% confidence interval [1.30-2.10]) and a body mass index higher than 35 kg.m⁻² (OR=3.46 [1.81-7.03]). In addition, severe inherited thrombophilia (OR=2.13 [1.32-3.51]) and non-O blood groups (OR=1.98 [1.57-2.49]) were strong genetic risk factors for VTE. Family history poorly predicted thrombophilia as its prevalence was similar in patients with or without first degree family history of VTE (29.3% vs 23.9%, p=0.09). In conclusion, this study confirms the influence of smoking and obesity and shows for the first time the impact of ABO blood group on the risk of VTE in women under COC. It also confirms the inaccuracy of the family history of VTE to detect inherited thrombophilia.

  5. Fluvastatin and the Breast Cancer Risk:A Meta-analysis of Observational Studies

    Institute of Scientific and Technical Information of China (English)

    Dong-Mei Liu; Jian Zhang; Wei Zhang; James Lu; Jian-Lun Han; Guang-Jun Hao; Sheng-Ming Ye

    2016-01-01

    Multiple studies have investigated the associations between fluvatatin and the risk of breast cancer (BC), but their results were conflicting. A meta-analysis of observational studies published regarding this subject was conducted in the present study. It aims to estimate the associations between fluvastatin use and the risk of BC. Pubmed and chinese national knowledge infrastructure (CNKI) database was searched up to January, 2015 to identify eligible observational studies, and the Newcastle-Ottawa Scale (NOS) was used to assess quality of the studies. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated (fixed effect model: Mantel-Haenszel). Heterogeneities were evaluated before the calculation. A sensitivity analysis was also conducted. In total, four studies contributed to the analysis. Overall, fluvastatin use negatively correlated with BC risk (RR=0.74, 95%CI=0.58, 0.95). In conclusion, fluvastatin use may reduce the risk of BC, but more research is needed to confirm this finding.

  6. Simulación de Plantas de Cogeneración de Ciclo Combinado usando ASPEN® Simulation of Combined Cycle Cogeneration Plants using ASPEN®

    Directory of Open Access Journals (Sweden)

    S.G. Guerra

    2005-01-01

    Full Text Available El objetivo de este trabajo fue generar una estrategia para el diseño de plantas de cogeneración de ciclo combinado, basada en el uso del simulador ASPEN®. La estrategia comprende la simulación, así como la definición de todas las variables clave del proceso. Como caso de estudio, se consideró satisfacer la demanda real de vapor y electricidad en una refinería usando un esquema de cogeneración de ciclo combinado. Aspectos relevantes de la situación actual de esta tecnología tal como el cálculo del punto de rocío ácido, para restringir la temperatura de los gases de salida, fueron considerados en el modelo. Se revisaron tres esquemas para determinar la mejor opción para el caso de estudio. Se concluye que la estrategia aplicada en este análisis puede generalizarse a otros casos y podría ser aplicada en el diseño futuro de plantas de cogeneración en MéxicoThe objective of this work was to generate a strategy for combined cycle cogeneration plant design based on the ASPEN® process simulator. The approach included process simulation as well as definition of all key variables. Satisfaction of real vapor and electricity demands in a refinery was considered as a case study, using a scheme of combined cycle cogeneration. Considered in the model were the outstanding aspects of the state of the art for this technology, such as the calculation of the dew acid point to restrict the temperature of exhaust gases. Three schemes were analyzed to determine the best option for the case under study. It was concluded that this approach could be extended to other cases and could be applied to the future design of cogeneration plants in Mexico.

  7. Análisis del ciclo de vida y las políticas de desarrollo de los clusters de empresas

    Directory of Open Access Journals (Sweden)

    Josep Capó-Vicedo

    2011-04-01

    Full Text Available En el presente trabajo se analizan dos aspectos muy concretos de las teorías que estudian las aglomeraciones territoriales de empresas o clusters; por una parte los factores que propician su desarrollo, estudiando de manera especial su origen y ciclo de vida y, por otra, aquellas políticas y acciones que pueden llevarse a cabo para potenciarlos. El trabajo busca obtener una visión de conjunto de los aspectos mencionados, a partir de estudios significativos realizados tanto desde el mundo académico como desde el mundo profesional. Entre las principales conclusiones del artículo destaca el hecho de que los clusters tienen siempre un ciclo de vida, sobre el cual tienen influencia tanto factores internos como externos al propio cluster. En este sentido se indican aquellos factores que pueden contribuir a que un cluster se mantenga en sus etapas de crecimiento y madurez el mayor tiempo posible, sin entrar en su fase de decadencia.In this piece, two very concrete aspects of the theories that deal with territorial agglomerations of companies (or clusters are analyzed. These are, on the one hand, the factors that cause the development of such clusters, studying their origins and life cycles in a particular way. On the other hand, we look at those policies and actions that can be carried out in order to harness these territorial agglomerations. The work aims to obtain a holistic vision of the aforementioned aspects, drawing from significant studies from both academia and the private sector. Among the main conclusions of the article, we highlight the fact that clusters always have a stressed life cycle, in which both internal and external factors influence the formation of clusters. In this sense, the factors that cause a cluster to remain in its stages of growth and maturity for as long as possible, without entering into a phase of decay, are indicated.

  8. Recepción televisiva en la adolescencia: ciclo de vida y gramáticas de reconocimiento

    Directory of Open Access Journals (Sweden)

    Lapuente, Mariano

    2010-01-01

    Full Text Available [es] Este trabajo, producto de una investigación realizada en el Instituto de Comunicación y Diseño (INCOD de la Universidad Argentina de la Empresa (UADE, se dirige a describir algunos de los procesos de producción de sentido que guían la selección y preferencia de programas en el telespectador adolescente1. Es intención avanzar aquí sobre los modos en que un ciclo de vida ejerce su influencia modalizando y condicionando el encuentro que mantiene con la televisión. Nos interesa describir especialmente el modo en que la adolescencia se convierte en una vía de aproximación al actor que se encuentra en la recepción de medios. Para ello hacemos explícito primero nuestro enfoque, circunscribimos una programación que constituye «la pantalla adolescente de la televisión de aire local de 2008» y nos detenemos en las reglas que la adolescencia activa en la recepción de sus programas. [en] This work is part of a study being conducted at the Institute of Design and Communication (INCOD at the Universidad Argentina de la Empresa (UADE. Its main objective is to describe the processes by which the adolescent selects and consumes TV programs. In this study, it is our goal to provide an understanding of how the cycle of life influences, modulates and conditions the relation that the consumer has with the television. We are particularly interested in the way the adolescent functions, as a way of approaching the consumer in the act of media reception. Our work is focused on the “adolescent screen in local television in 2008” from which we analyze the rules that teenagers activate upon the reception of some of its programs.

  9. Cereal fiber intake may reduce risk of gastric adenocarcinomas : The EPIC-EURGAST study

    NARCIS (Netherlands)

    Mendez, M. A.; Pera, Guillem; Aguclo, Antonio; Bueno-de-Mesquita, H. Bas; Palli, Domenico; Boeing, Heiner; Carneiro, Ftima; Berrino, Franco; Sacerdote, Carlotta; Tumino, Rosario; Panico, Salvatore; Berglund, Goeran; Manjer, Jonas; Johansson, Ingegerd; Stenling, Roger; Martinez, Carmen; Dorronsoro, Miren; Barricarte, Aurelio; Tormo, Maria J.; Quiros, Jose R.; Allen, Naomi; Key, Timothy J.; Bingham, Sheila; Linseisen, Jakob; Kaaks, Rudolf; Overvad, Kim; Jensen, Majken; Olsen, Anja; Tjonneland, Anne; Peeters, Petra H. M.; Numans, Mattijs E.; Ocke, Marga C.; Clavel-Chapelon, Francoise; Boutron-Ruault, Marie-Christine; Trichopoulou, Antonia; Lund, Eiliv; Slimani, Nadia; Jenab, Mazda; Ferrari, Pietro; Riboli, Elio; Gonzalez, Carlos A.

    2007-01-01

    Numerous case-control studies suggest dietary fiber may reduce risk of gastric cancer, but this has not been confirmed prospectively. A previous case-control study reported reduced risk of gastric cardia adenocarcinomas associated with cereal fiber, but not with fruit or vegetable fiber. To date, di

  10. Is diabetes mellitus a risk factor for open-angle glaucoma? The Rotterdam Study

    NARCIS (Netherlands)

    de Voogd, Simone; Ikram, M. Kamran; Wolfs, Roger C. W.; Jansonius, Nomdo M.; Witteman, Jacqueline C. M.; Hofman, Albert; de Jong, Paulus T. V. M.

    2006-01-01

    Purpose: To investigate whether diabetes mellitus is a risk factor for open-angle glaucoma (OAG). Design: Prospective population-based cohort study. Participants: Participants ages >= 55 years from the Rotterdam Study, The Netherlands. Methods: Participants at risk for incident OAG (iOAG) underwent

  11. Screening for gestational diabetes mellitus by a model based on risk indicators: a prospective study

    DEFF Research Database (Denmark)

    Jensen, Dorte; Mølsted-Pedersen, Lars; Beck-Nielsen, Henning;

    2003-01-01

    This study was performed to prospectively evaluate a screening model for gestational diabetes mellitus on the basis of clinical risk indicators.......This study was performed to prospectively evaluate a screening model for gestational diabetes mellitus on the basis of clinical risk indicators....

  12. Dietary folate and folate vitamers and the risk of prostate cancer in the Netherlands Cohort Study

    NARCIS (Netherlands)

    Verhage, B.A.J.; Cremers, P.; Schouten, L.J.; Goldbohm, R.A.; Brandt, P.A. van den

    2012-01-01

    Purpose: The aim of the present study was to examine the association between intake of folate, and specific folate vitamers, and the risk of advanced and total prostate cancer. Methods: The association between dietary folate and prostate cancer risk was evaluated in The Netherlands Cohort Study (NLC

  13. Is Diabetes Mellitus a Risk Factor for Open-Angle Glaucoma? The Rotterdam Study

    NARCIS (Netherlands)

    Voogd, S. de; Ikram, M.K.; Wolfs. R.C.W., [No Value; Jansonius, N.M.; Witteman, J.C.M.; Hofman, A.; de Jong, P.T.V.M.

    2006-01-01

    Purpose: To investigate whether diabetes mellitus is a risk factor for open-angle glaucoma (OAG). Design: Prospective population-based cohort study. Participants: Participants ages =55 years from the Rotterdam Study, The Netherlands. Methods: Participants at risk for incident OAG (iOAG) underwent at

  14. Longitudinal patterns and predictors of multiple health risk behaviors among adolescents : The TRAILS study

    NARCIS (Netherlands)

    de Winter, Andrea F; Visser, Leenke; Verhulst, Frank C; Vollebergh, Wilma A M; Reijneveld, Sijmen A

    2016-01-01

    BACKGROUND: Most studies on multiple health risk behaviors among adolescents have cross-sectionally studied a limited number of health behaviors or determinants. PURPOSE: To examine the prevalence, longitudinal patterns and predictors of individual and multiple health risk behaviors among adolescent

  15. Longitudinal patterns and predictors of multiple health risk behaviors among adolescents : The TRAILS study

    NARCIS (Netherlands)

    de Winter, Andrea F.; Visser, Leenke; Verhulst, Frank C.; Vollebergh, Wilma A M; Reijneveld, Sijmen A.

    2016-01-01

    BackgroundMost studies on multiple health risk behaviors among adolescents have cross-sectionally studied a limited number of health behaviors or determinants. PurposeTo examine the prevalence, longitudinal patterns and predictors of individual and multiple health risk behaviors among adolescents. M

  16. 78 FR 77138 - Proposed Collection; 60-day Comment Request: The Atherosclerosis Risk in Communities Study (ARIC)

    Science.gov (United States)

    2013-12-20

    ... Atherosclerosis Risk in Communities Study (ARIC) Summary: In compliance with the requirement of Section 3506(c) (2... days of the date of this publication. Proposed Collection: The Atherosclerosis Risk in Communities... primary objectives of the study are to: (1) investigate factors associated with both atherosclerosis...

  17. Association between Knee Osteoarthritis, Cardiovascular Risk Factors, and the Framingham Risk Score in South Koreans: A Cross-Sectional Study

    Science.gov (United States)

    Kim, Ho Sun; Shin, Joon-Shik; Lee, Jinho; Lee, Yoon Jae; Kim, Me-riong; Bae, Young-Hyeon; Park, Ki Byung; Lee, Eun-Jung; Kim, Joo-Hee

    2016-01-01

    Background Osteoarthritis is a significant burden on personal health and for social cost, and its prevalence is rising. Recent research has revealed an association between osteoarthritis and cardiovascular disease, and this study uses the Framingham risk score (FRS), which is widely used as a composite index of cardiovascular risk factors, to investigate the association between osteoarthritis and various cardiovascular risk factors. Methods A total 9,514 participants aged 50 years or older who received knee X-ray diagnosis of the 5th Korean National Health and Nutrition Examination Survey (total surveyees = 24,173) released by the Korean Centers for Disease Control and Prevention was included for analysis. Knee osteoarthritis patients were defined as participants with K-L grade ≥2 on knee X-ray regardless of knee pain. The association between major cardiovascular risk factors (blood pressure, diabetes, cholesterol, and smoking habits), FRS, and knee osteoarthritis was analyzed, adjusting for various covariates. Results Prevalence of knee osteoarthritis in Koreans aged ≥50 years was 36.6%, and higher in women (men: 24.9%, women: 45.4%). Prevalence of knee osteoarthritis in participants with hypertension was significantly higher than those without hypertension (fully adjusted odds ratio (OR) 1.26; 95% confidence interval (CI) 1.08–1.48). Knee osteoarthritis prevalence was also higher in participants with impaired fasting glucose or diabetes than those without (age, sex adjusted OR 1.19; 95% CI 1.00–1.41). Also, OR values increased statistically significantly with FRS as a continuous variable (fully adjusted OR 1.007; 95% CI 1.00–1.01). Conclusions Prevalence of knee osteoarthritis was associated with hypertension and diabetes, which are major cardiovascular risk factors, and the FRS. Further studies on FRS pertaining to its relationship with osteoarthritis are warranted. PMID:27764239

  18. Cancer and the risk for taking early retirement pension: a Danish cohort study

    DEFF Research Database (Denmark)

    Carlsen, Kathrine; Oksbjerg Dalton, Susanne; Frederiksen, Kirsten

    2008-01-01

    AIMS: The purpose of this study was to determine the risk for taking early retirement pension (ERP) in cancer survivors who were working at the time of diagnosis. METHODS: We conducted a nationwide and population based cohort study including 44,905 persons aged 30-60 years diagnosed with selected...... and the risk remained increased with up to 8 years of follow-up. CONCLUSIONS: We observed a significantly increased risk for taking early retirement up to 8 years after the cancer diagnosis and that the magnitude of the risk was dependent of cancer sites....

  19. Site-Specific ecological risk assessment. Case-study 2

    DEFF Research Database (Denmark)

    Jensen, John

    “Development of a decision support system for sustainable management of contaminated land by linking bioavailability, ecological risk and ground water pollution of organic pollutants”or in short “LIBERATION”. The presentation includes examples on how to scale and integrate the results from various scientific......The decision supporting and integrating assessment tool, TRIAD, is used site-specific on PAH- and heavy metal contaminated sites in Denmark. The various aspects of the TRIAD approach are used on a set of chemistry-, ecotoxicology- and ecology related data collected among others in the EU project...

  20. Lung cancer risk in never-smokers: a population-based case-control study of epidemiologic risk factors

    Directory of Open Access Journals (Sweden)

    Shepherd Frances A

    2010-06-01

    Full Text Available Abstract Background We conducted a case-control study in the greater Toronto area to evaluate potential lung cancer risk factors including environmental tobacco smoke (ETS exposure, family history of cancer, indoor air pollution, workplace exposures and history of previous respiratory diseases with special consideration given to never smokers. Methods 445 cases (35% of which were never smokers oversampled by design between the ages of 20-84 were identified through four major tertiary care hospitals in metropolitan Toronto between 1997 and 2002 and were frequency matched on sex and ethnicity with 425 population controls and 523 hospital controls. Unconditional logistic regression models were used to estimate adjusted odds ratios (OR and 95% confidence intervals (CI for the associations between exposures and lung cancer risk. Results Any previous exposure to occupational exposures (OR total population 1.6, 95% CI 1.4-2.1, OR never smokers 2.1, 95% CI 1.3-3.3, a previous diagnosis of emphysema in the total population (OR 4.8, 95% CI 2.0-11.1 or a first degree family member with a previous cancer diagnosis before age 50 among never smokers (OR 1.8, 95% CI 1.0-3.2 were associated with increased lung cancer risk. Conclusions Occupational exposures and family history of cancer with young onset were important risk factors among never smokers.

  1. A Cohort Study on Risk Factors of Lung Cancer in Yunnan Tin Miners

    Directory of Open Access Journals (Sweden)

    Yong JIANG

    2013-04-01

    Full Text Available Background and objective Smoking is a major cause of lung cancer. Studies of lung cancer among miners have shown that occupational exposure also played an important role. The aim of this study is to investigate radon, cigarette use and other risk factors of lung cancer in Yunnan tin miners and to provide a scientific basis for the prevention and control of occupational lung cancer. Methods A prospective cohort study was conducted among Yunnan tin miners, the associations between potential risk factors for lung cancer were analyzed by multivariate Cox regression model. Effects of age at first radon exposure and radon exposure rate on lung cancer risk were analyzed. The relationship between cumulative working level month and lung cancer was analyzed according to smoking status. The joint effect of tobacco use and cumulative radon exposure was analyzed based on additive and multiplicative models. Results Increased risk of lung cancer was associated with age at enrollment, tobacco use, prior bronchitis, and cumulative arsenic and radon exposure, while higher education level was associated with decreased lung cancer risk. An inverse effect of radon exposure rate was observed. There was no significant association between lung cancer risk and first radon exposure age. There was a significant additive interaction between tobacco use and radon exposure on lung cancer risk. Conclusion Several risk factors may contribute to the high incidence of lung cancer in Yunnan tin miners. Further studies are warranted to evaluate joint effect of different risk factors.

  2. Social ties and risk for cancer--a prospective cohort study

    DEFF Research Database (Denmark)

    Bergelt, Corinna; Prescott, Eva; Grønbaek, Morten;

    2009-01-01

    (breast, lung, prostate and colon and rectum) were conducted with the Cox proportional hazards model, with adjustment for a number of well-known risk factors for cancer. RESULTS: While we found no significant association between social ties and risk for cancer in men, women with high social network scores......BACKGROUND: Poor social support and small social networks have been associated with increased risks for conditions such as coronary heart disease as well as with overall mortality. We investigated the association between social ties and risk for cancer. MATERIAL AND METHODS: The study sample...... had an increased risk for lung cancer of borderline significance (HR, 2.16; 95% CI, 1.02-4.60). The risks for breast cancer and colorectal cancers were not significantly increased in the same group of women. DISCUSSION: The results of this study do not support the hypothesis that social network size...

  3. El análisis del ciclo de vida en la cuantificación de desechos de dos productos elaborados a partir de langosta

    OpenAIRE

    Cruz Núñez, G.

    2010-01-01

    El Análisis del Ciclo de Vida (ACV) es un método para analizar y evaluar los efectos y cargas ambientales causados por un producto, proceso o actividad durante su ciclo de vida completo “de la cuna a la tumba”, constituye una herramienta integral orientada hacia el producto y analiza las consecuencias potenciales que el mismo pueda causar para el medio ambiente a lo largo de su ciclo de vida. En el trabajo se realiza, de manera preliminar, el ACV a dos productos elaborados a parti...

  4. La evolución tecnológica del disco artificial según la Teoría del ciclo de vida del producto

    OpenAIRE

    2010-01-01

    La Teoría del Ciclo de Vida del Producto (en adelante, TCVP) caracteriza el cambio tecnológico que experimenta un producto a lo largo de su ciclo de vida como una secuencia de variación-selección. Las fases iniciales del ciclo de vida de un producto están caracterizadas por una gran variedad tecnológica, debido a que existe una alta incertidumbre respecto a las prestaciones de las diferentes soluciones tecnológicas propuestas. Sin embargo, esta incertidumbre se reduce con el tiempo, y esta re...

  5. Transferências voluntárias e ciclo político-orçamentário no federalismo fiscal brasileiro

    Directory of Open Access Journals (Sweden)

    Ivan F. S. Ferreira

    2007-09-01

    Full Text Available RESUMO Este artigo apresenta um estudo econométrico sugerindo que as transferências inter-governamentais no Brasil são significantemente influenciadas por motivações político-partidárias. Diante desse fato estilizado, desenvolve-se uma extensão do modelo de Rogoff (1990 para analisar o efeito dessas transferências politicamente motivadas sobre os equilíbrios eleitoral e fiscal subnacionais. Mostra-se que as transferências politicamente motivadas podem anular o principal aspecto positivo do ciclo político-orçamentário. De fato, essas transferências podem, por um lado, eliminar o ciclo políticoorçamentário, resolvendo o problema de risco moral, mas, por outro lado, elas podem colocar no poder um titular incompetente, gerando um problema de seleção adversa.This article presents an econometric study suggesting that intergovernmental transfers to Brazilian municipalities are strongly partisan motivated. In light of that stylized fact, it develops an extension to Rogoff (1990's model to analyze the effect of partisan motivated transfers into sub-national electoral and fiscal equilibria. The main finding is that important partisan transfers may undo the positive selection aspect of political budget cycles. Indeed, partisan transfers may, on one hand, eliminate the political budget cycle, solving a moral hazard problem, but, on the other hand, they may retain an incompetent incumbent in office, bringing about an adverse selection problem.

  6. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015 : a systematic analysis for the Global Burden of Disease Study 2015

    OpenAIRE

    Forouzanfar, Mohammad H; Afshin, Ashkan; Alexander, Lily T; Anderson, H. Ross; Bhutta, Zulficiar A.; Biryukov, Stan; Brauer, Michael; Burnett, Richard; Cercy, Kelly; Charlson, Fiona J.; Cohen, Aaron J; Dandona, Lalit; Estep, Kara; Ferrari, Alize J.; Frostad, Joseph J.

    2016-01-01

    Background The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate att...

  7. High lifetime risk of cardiovascular disease vs low 10-year Framingham risk score in HIV-infected subjects under ART in Spain: the Coronator study

    Directory of Open Access Journals (Sweden)

    C Miralles

    2012-11-01

    Full Text Available Purpose: Due to the relative low age of HIV-infected patients, Framingham risk score (FRS usually estimates a low CVD risk. Lifetime risk estimations use the risk of developing CVD over the course of an individual's remaining lifetime and may be useful in communicating the risk of CVD to young patients. Our aim is to estimate the lifetime risk of CVD in a representative sample of HIV patients under antiretroviral therapy in Spain. Methods: Cross-sectional analysis in 10 HIV units across Spain, including information on demographics, HIV disease status, treatment history and cardiovascular risk factors of subject under ART. Lifetime CVD risk was calculated with the method of Berry et al, which classifies the lifetime risk in five mutually exclusive categories: 1. All risk factors are optimal; 2. At least one risk factor is not optimal; 3. At least one risk factor is elevated; 4. One major risk factor is present; and 5. Two or more major risk factors are present. Risk factors included are cholesterol level, blood pressure, diabetes and tobacco smoking. We grouped these five categories in two major groups, low-risk (groups 1+2+3 and high-risk category (groups 4+5. We calculated the prevalence of having a high lifetime risk, and its crude and aOR (adjusted by age, sex, place of origin, education level, transmission category, time since HIV diagnosis, CDC stage, current and nadir CD4 count, HCV coinfection, time on current and total ART, being on the first ART regimen, and PI vs. NNRTI regimen. Results: We included 839 subjects free of previous CVD disease: 72% men, median age 45.6y, median CD4 count 598 cells, median time since HIV diagnosis 11y, median time on ART 6.3y, 87% had undetectable VL. Estimated 10-year CVD risk was low (<5% in 78% of the patients, and intermediate (5–10% in 20%. Lifetime risk estimation shows a high risk profile for 71.4% of the population studied (≥1 major risk factors. Factors significantly and independently

  8. Risk Management Practices in Islamic Bank: A Case Study of Islami Bank Bangladesh Limited

    OpenAIRE

    Uddin, Md Akther

    2015-01-01

    Islamic banking industry has been growing rapidly for last three decades. As risk is inherent in banking business it is necessary to develop a comprehensive risk management framework and process. In this paper, a humble attempt has been made to study and analyze risk management practices of Islami Bank Bangladesh Limited (IBBL), one of the leading Islamic banks in Bangaladesh. Annual reports of IBBL and 7 other full-fledged Islamic banks, Bangladesh Bank, the central bank of Bangladesh, publi...

  9. Technical and environmental aspects of combined cycle power stations with integrated gasification (CCGI); Aspectos tecnicos y medioambientales de las centrales de ciclo combinado con gasificacion integrada (CCGI)

    Energy Technology Data Exchange (ETDEWEB)

    Beltran Mora, Hector Alejandro; Urias Romero, Francisco [Facultad de Ingenieria, Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)

    2004-06-15

    A description is presented of the operation of the Combined Cycle Power Stations with Integrated Gasification (CCGI) where the use of solid fuels (coal, vacuum residues, petroleum coke, and biomass) or liquids is possible in a thermal power station with the efficiency and many of the own environmental benefits of the combined cycles. The gasification process is analyzed, that is a thermo-chemical process by means of which a fuel that is in solid state or liquid becomes to the gaseous state by means of a partial oxidation and the obtained gas of this process is called synthesis gas (syngas, by its abbreviations in English) that is used in Combined Cycle Power Stations as a substitute for the natural gas. Also the other components of this type of power stations are shown, such as the air separating unit, and some of the modifications that are due to make to adapt a gas turbine so that it uses syngas, and the considerations of their integration with the air separating unit to optimize the operation of the plant are detailed. A comparison of efficiency values of power stations CCGI with the conventional carbon-electric and the power stations of combined cycle that use natural gas is also shown. Finally the emissions of pollutants of SO{sub 2}, NO{sub x} and CO{sub 2} are analyzed. The possibility of using fuels like petroleum coke and vacuum tower residues that are produced in the Cadereyta refinery is studied for the possible construction of a CCGI power station in Mexico. [Spanish] Se presenta la descripcion del funcionamiento de las centrales ciclo combinado con gasificacion integrada (CCGI) donde es posible el uso de combustibles solidos (carbon, residuos de vacio, coque de petroleo, biomasa) o liquidos en una central termica con la eficiencia y muchos de los beneficios ambientales propios de los ciclos combinados. Se analiza el proceso de gasificacion, que es un proceso termoquimico mediante el cual se convierte un combustible que se encuentra en estado solido o

  10. Sincronização do ciclo celular em meristema radicular de baru (Dipteryx alata Vog. Sinchronization of cell cycle in root meristem of baru (Dipteryx alata Vog.

    Directory of Open Access Journals (Sweden)

    Giovana Augusta Torres

    2003-04-01

    Full Text Available Uma das dificuldades de se conduzir estudos citogenéticos em espécies vegetais nativas do cerrado é a ocorrência de baixos índices metafásicos no meristema radicular. O incremento dos índices mitótico e metafásico em células de pontas de raiz tem sido obtido em várias espécies com a sincronização do ciclo celular por meio de hidroxiuréia (HU. Neste trabalho foram determinadas as condições ótimas para a sincronização eficiente do ciclo em células meristemáticas de raízes de baru (Dipteryx alata Vog.. Foram testadas quatro concentrações de HU (0,00; 1,25; 2,50; 5,00 e 10,00 mM, três tempos de exposição das raízes (10, 15 e 20 h e dois tempos de recuperação do ciclo (5 e 10 h. As melhores respostas foram obtidas com exposição das raízes, de cerca de 1 cm, à solução de HU 3,5 mM, por 20 horas, com posterior recuperação do ciclo em água destilada por 5 horas. O índice de 45% de células em divisão representou um incremento de cerca de 5 vezes em relação à testemunha, ao passo que para células em metáfases, o índice de 22,6% foi cerca de 10 vezes superior. Portanto, o uso dessa estratégia mostrou-se bastante eficiente para a obtenção de grande quantidade de cromossomos para análise citogenética do baru.A major difficulty in cytogenetic studies of plant species from "cerrado" is the low metaphasic index in root tip cells. Cell cycle synchronization, by using hydroxyurea (HU, has been successfully used in order to obtain high mitotic and metaphasic index in several species. The goal of this work was to optimize conditions for efficient synchronization of Dipteryx alata root tip meristematic cells. Different levels of hydroxyurea (0, 1.25, 2.50, 5.00, and 10.00 mM, periods of treatment (10, 15, and 20 h and periods of cell cycle recovery (5 and 10 h were tested. Best results were achieved by treating 10-mm long roots with 3.5 mM hydroxyurea, for 20 h and incubating for 5 h in distilled water. The

  11. A study of the perception of health risks among college students in China.

    Science.gov (United States)

    Zhang, Chenggang; Fan, Jingbo

    2013-05-27

    The present survey was designed to investigate the perception of health risks among college students in China. The data are the responses of a sample of 3,069 college students at one university to surveys that include measures of several dimensions of public judgments about fifteen specific hazards. Chinese college students conveyed their concerns as falling into three broad categories: Environmental (e.g., global warming, natural catastrophes, the ozone hole, air pollution, chemical pollution, pesticides in food), Technological (e.g., nuclear power stations, thermal power, genetically modified food, medical X-rays), and Social (cigarette smoking, drinking alcohol, overtime study or work, mental stress, motor vehicle accidents). The data were collected with a self-report questionnaire. Descriptive statistics were used to illustrate the levels of perceived risk according to the percent of "high risk" responses as well as the mean response values. Generally, the hazards that were perceived as posing the greatest health risk were those belonging to the social health risks; items related to technology risks received the lowest percentage of "high health risk" rankings. Traditional environmental risks such as natural catastrophes, pollution issues (chemical pollution, air pollution), and pesticides in food were ranked as being relatively high risks. The respondents were less concerned about new emerging issues and long-term environmental risks (global warming). In this survey, motor vehicle accidents were considered to be a "high health risk" by the greatest percentage of respondents. Generally speaking, the female respondents' degree of recognition of health risks is higher than that of male respondents. Only for the item of smoking was the male respondents' degree higher than that of females. There is also a geographic imbalance in the health risk perceptions. The degree of recognition of health risks from respondents in municipalities is generally lower than that of

  12. A cohort study on the relationship between cerebrovascular hemodynamic changing and risk of strok

    Institute of Scientific and Technical Information of China (English)

    郭吉平

    2013-01-01

    Objective To study the role of cerebrovascular hemodynamic indexes(CVHI)changing in stroke and to provide reference for stroke prevention and risk factor study.Methods From 2003 to 2004,participants aged 40 years

  13. Men at risk; a qualitative study on HIV risk, gender identity and violence among men who have sex with men who report high risk behavior in Kampala, Uganda.

    Directory of Open Access Journals (Sweden)

    Rachel King

    Full Text Available In Uganda, men who have sex with men (MSM are at high risk for HIV. Between May 2008 and February 2009 in Kampala, Uganda, we used respondent driven sampling (RDS to recruit 295 MSM≥18 years who reported having had sex with another man in the preceding three months. The parent study conducted HIV and STI testing and collected demographic and HIV-related behavioral data through audio computer-assisted self-administered interviews. We conducted a nested qualitative sub-study with 16 men purposively sampled from among the survey participants based on responses to behavioral variables indicating higher risk for HIV infection. Sub-study participants were interviewed face-to-face. Domains of inquiry included sexual orientation, gender identity, condom use, stigma, discrimination, violence and health seeking behavior. Emergent themes included a description of sexual orientation/gender identity categories. All groups of men described conflicting feelings related to their sexual orientation and contextual issues that do not accept same-sex identities or behaviors and non-normative gender presentation. The emerging domains for facilitating condom use included: lack of trust in partner and fear of HIV infection. We discuss themes in the context of social and policy issues surrounding homosexuality and HIV prevention in Uganda that directly affect men's lives, risk and health-promoting behaviors.

  14. Men at risk; a qualitative study on HIV risk, gender identity and violence among men who have sex with men who report high risk behavior in Kampala, Uganda.

    Science.gov (United States)

    King, Rachel; Barker, Joseph; Nakayiwa, Sylvia; Katuntu, David; Lubwama, George; Bagenda, Danstan; Lane, Tim; Opio, Alex; Hladik, Wolfgang

    2013-01-01

    In Uganda, men who have sex with men (MSM) are at high risk for HIV. Between May 2008 and February 2009 in Kampala, Uganda, we used respondent driven sampling (RDS) to recruit 295 MSM≥18 years who reported having had sex with another man in the preceding three months. The parent study conducted HIV and STI testing and collected demographic and HIV-related behavioral data through audio computer-assisted self-administered interviews. We conducted a nested qualitative sub-study with 16 men purposively sampled from among the survey participants based on responses to behavioral variables indicating higher risk for HIV infection. Sub-study participants were interviewed face-to-face. Domains of inquiry included sexual orientation, gender identity, condom use, stigma, discrimination, violence and health seeking behavior. Emergent themes included a description of sexual orientation/gender identity categories. All groups of men described conflicting feelings related to their sexual orientation and contextual issues that do not accept same-sex identities or behaviors and non-normative gender presentation. The emerging domains for facilitating condom use included: lack of trust in partner and fear of HIV infection. We discuss themes in the context of social and policy issues surrounding homosexuality and HIV prevention in Uganda that directly affect men's lives, risk and health-promoting behaviors.

  15. A Pilot Study on Developing a Standardized and Sensitive School Violence Risk Assessment with Manual Annotation.

    Science.gov (United States)

    Barzman, Drew H; Ni, Yizhao; Griffey, Marcus; Patel, Bianca; Warren, Ashaki; Latessa, Edward; Sorter, Michael

    2016-08-16

    School violence has increased over the past decade and innovative, sensitive, and standardized approaches to assess school violence risk are needed. In our current feasibility study, we initialized a standardized, sensitive, and rapid school violence risk approach with manual annotation. Manual annotation is the process of analyzing a student's transcribed interview to extract relevant information (e.g., key words) to school violence risk levels that are associated with students' behaviors, attitudes, feelings, use of technology (social media and video games), and other activities. In this feasibility study, we first implemented school violence risk assessments to evaluate risk levels by interviewing the student and parent separately at the school or the hospital to complete our novel school safety scales. We completed 25 risk assessments, resulting in 25 transcribed interviews of 12-18 year olds from 15 schools in Ohio and Kentucky. We then analyzed structured professional judgments, language, and patterns associated with school violence risk levels by using manual annotation and statistical methodology. To analyze the student interviews, we initiated the development of an annotation guideline to extract key information that is associated with students' behaviors, attitudes, feelings, use of technology and other activities. Statistical analysis was applied to associate the significant categories with students' risk levels to identify key factors which will help with developing action steps to reduce risk. In a future study, we plan to recruit more subjects in order to fully develop the manual annotation which will result in a more standardized and sensitive approach to school violence assessments.

  16. Combining Climate Scenarios and Risk Management Approach—A Finnish Case Study

    Directory of Open Access Journals (Sweden)

    Riitta Molarius

    2015-11-01

    Full Text Available Climate change impacts on nature and the environment have been widely discussed and studied. Traditionally, a company’s continuity management is based on risk analysis. There are also attempts to implement scenario-based methods in the risk management procedures of companies. For industrial decision makers, it is vital to acknowledge the impacts of climate change with regards to their adaptation strategies. However, a scenario-based approach is not always the most effective way to analyze these risks. This paper investigates the integration of scenario and risk-based methods for a company’s adaptation planning. It considers the uncertainties of the climate change scenarios and the recognized risks as well as suitable adaptation strategies. The paper presents the results of climate risk analysis prepared for two Finnish hydropower plants. The introduced method was first piloted in 2008 and then again in 2015. The update of the analysis pointed out that at the company level, the climate risks and other risks originating from governmental or political decisions form an intertwined wholeness where the origin of the risk is difficult to outline. It seems that, from the business point of view, the main adaptation strategies suggested by the integrated risk and scenarios approach are those that support buying “safety margins” in new investments and reducing decision time horizons. Both of these adaptation strategies provide an advantage in the circumstances where also political decisions and societal changes have a great effect on decision making.

  17. Identifying patient preferences for communicating risk estimates: A descriptive pilot study

    Directory of Open Access Journals (Sweden)

    O'Connor Annette M

    2001-08-01

    Full Text Available Abstract Background Patients increasingly seek more active involvement in health care decisions, but little is known about how to communicate complex risk information to patients. The objective of this study was to elicit patient preferences for the presentation and framing of complex risk information. Method To accomplish this, eight focus group discussions and 15 one-on-one interviews were conducted, where women were presented with risk data in a variety of different graphical formats, metrics, and time horizons. Risk data were based on a hypothetical woman's risk for coronary heart disease, hip fracture, and breast cancer, with and without hormone replacement therapy. Participants' preferences were assessed using likert scales, ranking, and abstractions of focus group discussions. Results Forty peri- and postmenopausal women were recruited through hospital fliers (n = 25 and a community health fair (n = 15. Mean age was 51 years, 50% were non-Caucasian, and all had completed high school. Bar graphs were preferred by 83% of participants over line graphs, thermometer graphs, 100 representative faces, and survival curves. Lifetime risk estimates were preferred over 10 or 20-year horizons, and absolute risks were preferred over relative risks and number needed to treat. Conclusion Although there are many different formats for presenting and framing risk information, simple bar charts depicting absolute lifetime risk were rated and ranked highest overall for patient preferences for format.

  18. Enhancing local action planning through quantitative flood risk analysis: a case study in Spain

    Science.gov (United States)

    Castillo-Rodríguez, Jesica Tamara; Escuder-Bueno, Ignacio; Perales-Momparler, Sara; Ramón Porta-Sancho, Juan

    2016-07-01

    This article presents a method to incorporate and promote quantitative risk analysis to support local action planning against flooding. The proposed approach aims to provide a framework for local flood risk analysis, combining hazard mapping with vulnerability data to quantify risk in terms of expected annual affected population, potential injuries, number of fatalities, and economic damages. Flood risk is estimated combining GIS data of loads, system response, and consequences and using event tree modelling for risk calculation. The study area is the city of Oliva, located on the eastern coast of Spain. Results from risk modelling have been used to inform local action planning and to assess the benefits of structural and non-structural risk reduction measures. Results show the potential impact on risk reduction of flood defences and improved warning communication schemes through local action planning: societal flood risk (in terms of annual expected affected population) would be reduced up to 51 % by combining both structural and non-structural measures. In addition, the effect of seasonal population variability is analysed (annual expected affected population ranges from 82 to 107 %, compared with the current situation, depending on occupancy rates in hotels and campsites). Results highlight the need for robust and standardized methods for urban flood risk analysis replicability at regional and national scale.

  19. General practitioners’ use of absolute risk versus individual risk factors in cardiovascular disease prevention: an experimental study

    OpenAIRE

    Jansen, Jesse; Bonner, Carissa; McKinn, Shannon; Irwig, Les; Glasziou, Paul ,; Doust, Jenny; Teixeira-Pinto, Armando; Hayen, Andrew; Turner, Robin; McCaffery, Kirsten

    2014-01-01

    Objective To understand general practitioners’ (GPs) use of individual risk factors (blood pressure and cholesterol levels) versus absolute risk in cardiovascular disease (CVD) risk management decision-making. Design Randomised experiment. Absolute risk, systolic blood pressure (SBP), cholesterol ratio (total cholesterol/high-density lipoprotein (TC/HDL)) and age were systematically varied in hypothetical cases. High absolute risk was defined as 5-year risk of a cardiovascular event >15%, hig...

  20. Liquidity Risk on Banking Industry: Comparative Study Between Islamic Bank and Conventional Bank in Indonesia

    Directory of Open Access Journals (Sweden)

    Harjum Muharam

    2015-11-01

    Full Text Available Conventional and Islamic banks approximately are similar in risk summary. Therefore it needs further observations to control their liquidity risk. This study investigates the influence of CAR, profitability rasios, NIM, liquidity gaps, and RLA belongs to liquidity risk on banking industry. The statistical analysis concluded that there are negative and significant influence of CAR and ROE to liquidity risk on conventional banks, while ROA and RLA have positive and significant effect. In Islamic banks, a positive and significant impact of NIM and ROE to dependent variable, whereas liquidity gaps and RLA have significat effect.DOI: 10.15408/aiq.v5i2.2118

  1. Traffic risk behavior and perceptions of Thai motorcyclists: A case study

    Directory of Open Access Journals (Sweden)

    Prathurng Hongsranagon

    2011-07-01

    Full Text Available This study aimed to investigate Thai motorcyclists' traffic risk behavior and their perceptions of it, information of value in the design and implementation of public health policies and campaigns for the reduction of road injuries. Data was collected by a self-administered questionnaire completed by 399 motorcyclists in Muang Krabi district, Krabi province, Thailand. The questionnaire focused on the respondents' perceptions of general traffic risks and the specific risks at 3 identified hazardous sites. The results of the survey indicated that the correct fastening of helmet straps had a relationship with responsible traffic risk perceptions.

  2. Suicide risk in relation to level of urbanicity - a population-based linkage study

    DEFF Research Database (Denmark)

    Qin, Ping

    2005-01-01

    from various Danish longitudinal registers. Data were analysed with conditional logistic regression. RESULTS: This study confirms that people living in more urbanized areas are at a higher risk of suicide than their counterparts in less urbanized areas. However, this excess risk is largely eliminated...... when adjusted for personal marital, income, and ethnic differences; it is even reversed when further adjusted for psychiatric status. Moreover, the impact of urbanicity on suicide risk differs significantly by sex and across age. Urban living reduces suicide risk significantly among men, especially...

  3. Study on the evaluation system for the coal safety management based on risk pre-control

    Institute of Scientific and Technical Information of China (English)

    LI Xin-chun; XU Hai-xia; WANG Pei; SONG Xue-feng

    2009-01-01

    The new type of risk management is process management.First,the hazard sources are identified before coal mine accidents occur,and then the pre-control measure and information monitoring method based on classifying the hidden hazard sources are given.Lastly,the risk pre-alarm and risk control method are confirmed,the management standard and management measure are used to eliminate the hidden hazard sources.In this study,an evaluation system is built to evaluate the result of risk management.

  4. Incidence of cardiovascular events after kidney transplantation and cardiovascular risk scores: study protocol

    Directory of Open Access Journals (Sweden)

    Lorenzo-Aguiar Dolores

    2011-01-01

    Full Text Available Abstract Background Cardiovascular disease (CVD is the major cause of death after renal transplantation. Not only conventional CVD risk factors, but also transplant-specific risk factors can influence the development of CVD in kidney transplant recipients. The main objective of this study will be to determine the incidence of post-transplant CVD after renal transplantation and related factors. A secondary objective will be to examine the ability of standard cardiovascular risk scores (Framingham, Regicor, SCORE, and DORICA to predict post-transplantation cardiovascular events in renal transplant recipients, and to develop a new score for predicting the risk of CVD after kidney transplantation. Methods/Design Observational prospective cohort study of all kidney transplant recipients in the A Coruña Hospital (Spain in the period 1981-2008 (2059 transplants corresponding to 1794 patients. The variables included will be: donor and recipient characteristics, chronic kidney disease-related risk factors, pre-transplant and post-transplant cardiovascular risk factors, routine biochemistry, and immunosuppressive, antihypertensive and lipid-lowering treatment. The events studied in the follow-up will be: patient and graft survival, acute rejection episodes and cardiovascular events (myocardial infarction, invasive coronary artery therapy, cerebral vascular events, new-onset angina, congestive heart failure, rhythm disturbances and peripheral vascular disease. Four cardiovascular risk scores were calculated at the time of transplantation: the Framingham score, the European Systematic Coronary Risk Evaluation (SCORE equation, and the REGICOR (Registre Gironí del COR (Gerona Heart Registry, and DORICA (Dyslipidemia, Obesity, and Cardiovascular Risk functions. The cumulative incidence of cardiovascular events will be analyzed by competing risk survival methods. The clinical relevance of different variables will be calculated using the ARR (Absolute Risk

  5. Oral contraceptives and breast cancer risk in the international BRCA1/2 carrier cohort study

    DEFF Research Database (Denmark)

    Brohet, Richard M; Goldgar, David E; Easton, Douglas F

    2007-01-01

    oral contraceptive use and risk of breast cancer among BRCA1/2 carriers. PATIENTS AND METHODS In the International BRCA1/2 Carrier Cohort study (IBCCS), a retrospective cohort of 1,593 BRCA1/2 mutation carriers was analyzed with a weighted Cox regression analysis. Results We found an increased risk...... was found among BRCA1/2 mutation carriers that current use of oral contraceptives is associated with risk of breast cancer more strongly than is past use, as is found in the general population. However, duration of use, especially before first full-term pregnancy, may be associated with an increasing risk...

  6. Risk of Cerebral Infarction in Japanese Hemodialysis Patients: Miyazaki Dialysis Cohort Study (MID study

    Directory of Open Access Journals (Sweden)

    Tatsunori Toida

    2016-07-01

    Full Text Available Background/Aims: Predictors including the preventive effects of antiplatelet and anticoagulant drugs on cerebral infarction (CI events have not yet been clarified in dialysis patients. The aim of the present study was to examine the risk of CI and preventive effects of these drugs in Japanese hemodialysis patients. Methods: Patients receiving maintenance hemodialysis (n=1,551, median age (interquartile range, 69.0 (59.0-78.0 years; 41.5% female were enrolled in the Miyazaki Dialysis Cohort Study and prospectively followed-up for 3 years. Kaplan-Meier and Cox's regression analyses were used to clarify the risk of CI. Results: Eighty-four patients developed CI at an incidence of 21.5/1000 patients per year. The presence of a previous history of CI, atrial fibrillation (AF, and diabetes mellitus in addition to age were also identified as predictive factors for new CI, whereas no relationship was observed between antiplatelet and/or anticoagulant usage and CI. Furthermore, no significant difference was noted in the frequency of CI events between patients with AF who received warfarin and those who did not. Conclusions: The incidence of CI was higher in dialysis patients with a previous history of CI and AF; however, the preventive effects of antiplatelet/anticoagulant drugs on the development of CI were not evident.

  7. Dairy consumption and ovarian cancer risk in the Netherlands Cohort Study on diet and cancer

    NARCIS (Netherlands)

    Mommers, M.; Schouten, L.J.; Goldbohm, R.A.; Brandt, P.A. van den

    2006-01-01

    Ovary cancer risk in relation to consumption of dairy products was investigated using a self-administered questionnaire on dietary habits and other risk factors for cancer, which was completed in 1986 by 62 573 postmenopausal women participating in the Netherlands Cohort Study. Follow-up for cancer

  8. Use of methimazole and risk of acute pancreatitis: A case–control study in Taiwan

    Directory of Open Access Journals (Sweden)

    Shih-Wei Lai

    2016-01-01

    Conclusions: Our study does not detect a substantial association between the use of methimazole and risk of acute pancreatitis on the basis of systematic analysis. There appears to be a discrepancy between case reports and our systematic analysis about the association between the use of methimazole and risk of acute pancreatitis.

  9. Treatment with rivastigmine or galantamine and risk of urinary incontinence : results from a Dutch database study

    NARCIS (Netherlands)

    Kroger, Edeltraut; Van Marum, Rob; Souverein, Patrick; Carmichael, Pierre Hugues; Egberts, Toine

    2015-01-01

    Treatment of Alzheimer disease (AD) with cholinesterase inhibitors (ChEIs) may increase the risk of urinary incontinence (UI). Objective: To assess whether ChEI use was associated with the risk of UI among older patients with AD. Methods: A crossover cohort study using the PHARMO Record Linkage Syst

  10. Magnesium intake and colorectal cancer risk in the Netherlands Cohort Study

    NARCIS (Netherlands)

    Brandt, P.A. van den; Smits, K.M.; Goldbohm, R.A.; Weijenberg, M.P.

    2007-01-01

    Energy-adjusted magnesium intake was nonsignificantly inversely related to risk of colorectal cancer (n=2328) in the Netherlands Cohort Study on Diet and Cancer that started in 1986 (n=58 279 men and 62 573 women). Statistically significant inverse trends in risk were observed in overweight subjects

  11. Work-site musculoskeletal pain risk estimates by trained observers - a prospective cohort study

    NARCIS (Netherlands)

    Coenen, P.; Kingma, I.; Boot, C.R.L.; Douwes, M.; Bongers, P.M.; Dieën, J.H. van

    2012-01-01

    Work-related musculoskeletal pain (MSP) risk assessments by trained observers are often used in ergonomic practice; however, the validity may be questionable. We investigated the predictive value of work-site MSP risk estimates in a prospective cohort study of 1745 workers. Trained observers estimat

  12. The potential of large studies for building genetic risk prediction models

    Science.gov (United States)

    NCI scientists have developed a new paradigm to assess hereditary risk prediction in common diseases, such as prostate cancer. This genetic risk prediction concept is based on polygenic analysis—the study of a group of common DNA sequences, known as singl

  13. H15-42: CFD analysis for risk analysis in urban environments - Tilburg city case study

    NARCIS (Netherlands)

    Hulsbosch-Dam, C.; Mack, A.; Ratingen, S. van; Rosmuller, N.; Trijssenaar, I.

    2013-01-01

    For risk analysis studies, relatively simple dispersion models are generally applied, such as Gaussian dispersion and dense gas dispersion models. For rail transport risk analyses in the Netherlands, fixed consequence distances are applied for various standard scenarios of hazardous materials releas

  14. Risk of atrial fibrillation among bisphosphonate users: a multicenter, population-based, Italian study

    NARCIS (Netherlands)

    L. Herrera (Lizbeth); I. Leal (Ingrid); F. Lapi (Francesco); M.J. Schuemie (Martijn); V. Arcoraci (Vincenzo); F. Cipriani (Francesco); E. Sessa (E.); A. Vaccheri (Alberto); C. Piccinni (C.); T. Staniscia (Tommaso); A. Vestri (Annarita); M. Di Bari (M.); G. Corrao (Giovanni); A. Zambon (A.); D Gregori (Dario); F. Carle (F.); M.C.J.M. Sturkenboom (Miriam); G. Mazzaglia (Giampiero); G. Trifirò (Gianluca)

    2015-01-01

    textabstractSummary: Bisphosphonate treatment is used to prevent bone fractures. A controversial association of bisphosphonate use and risk of atrial fibrillation has been reported. In our study, current alendronate users were associated with a higher risk of atrial fibrillation as compared with tho

  15. Youth Perspectives on Risk and Resiliency: A Case Study from Juiz De Fora, Brazil

    Science.gov (United States)

    Morrison, Penelope; Nikolajski, Cara; Borrero, Sonya; Zickmund, Susan

    2014-01-01

    The present work seeks to contribute to studies of cross-cultural risk and resiliency by presenting results from qualitative research with adolescents attending programs for at-risk youth in Juiz de Fora, Brazil. In 1990, Brazil introduced the Child and Adolescent Act (ECA), a significant piece of legislation that has had a direct impact on how…

  16. Phase 2 study of adjuvant intravesical instillations of apaziquone for high risk nonmuscle invasive bladder cancer.

    NARCIS (Netherlands)

    Hendricksen, K.; Cornel, E.B.; Reijke, T.M. de; Arentsen, H.C.; Chawla, S.; Witjes, J.A.

    2012-01-01

    PURPOSE: We studied the safety and efficacy of multiple adjuvant apaziquone instillations in patients with high risk nonmuscle invasive bladder cancer. MATERIALS AND METHODS: Patients with high risk nonmuscle invasive urothelial carcinoma of the bladder underwent transurethral resection of all bladd

  17. Risk factors for patellar tendinopathy in basketball and volleyball players : A cross-sectional study

    NARCIS (Netherlands)

    Van der Worp, H.; Van Ark, M.; Zwerver, J.; Van den Akker-Scheek, I.

    2012-01-01

    Patellar tendinopathy (PT) has a multifactorial etiology, and many possible risk factors have been described in the literature. The findings are conflicting, though, and most research has been conducted on elite athletes. The aim of the current study is to determine the risk factors for PT in a larg

  18. A Case-Control Study of Risk Factors for Prostate Cancer in Iran

    Directory of Open Access Journals (Sweden)

    Mahmoud Mahmoudi

    2010-02-01

    Full Text Available Prostate cancer is a major cause of morbidity and mortality in Iran, yet there are few studies examining risk factors specific to the Iranian context. We conducted a case-control study to explore risk factors for prostate cancer in Mazandaran, Iran from 2005 to 2008. The cases were 137 men with clinicopathologically confirmed prostate cancer. Controls were 137 neighborhood and age match men without prostate cancer by PSA and digit examination. Analysis comprised an exploratory stage to identify potential risk factors, defined as variables associated with case status at the P < 0.20 level in conditional logistic regression. A second stage included all potential risk factors in multiple conditional logistic regression analysis, retaining those associated with prostate cancer at the P < 0.05 level. Potential risk factors for prostate cancer in exploratory analysis included family history of prostate cancer, history of other cancer, prostatitis, alcohol consumption, pipe or hookah smoking, walking to work, duration of occupational physical activity, intensity of occupational physical activity, body mass index, and older age. Multivariate analysis found intensity of occupational physical activity, prostatitis, and older age as independent predictors of increased risk for prostate cancer in this Iranian population. Our study confirms several recognized risk factors for prostate cancer, contributes evidence to the discussions of other hypothesized risk factors, and points to potentially new factors. Findings, along with confirmatory studies, can help guide efforts for early detection, treatment, and prevention for this common malignancy that is set to increase in Iran in future decades.

  19. Fracture risk in Danish men with prostate cancer: a nationwide register study

    DEFF Research Database (Denmark)

    Abrahamsen, Bo; Nielsen, Morten F; Eskildsen, Peter;

    2007-01-01

    OBJECTIVE: To assess the risk of fracture attributable to prostate cancer, and the impact of exposure to prescribed gonadotrophin-releasing hormone agonists and antiandrogens on this risk in a nationwide, population-based case-control study. PATIENTS AND METHODS: Data from the Danish National...

  20. Incidence, Risk Factors, and Outcomes for Enterococcus spp. Blood Stream Infections: A Population-Based Study

    Directory of Open Access Journals (Sweden)

    E.O. Billington

    2014-09-01

    Conclusions: This is the second population-based study to assess the risk factors for enterococcal BSI and compare the characteristics of infection with E. faecalis and E. faecium. Results suggest that BSI with E. faecalis and E. faecium should be regarded as two clinically different entities with unique sets of risk factors and microbiologic characteristics.

  1. A Cardiovascular Risk Reduction Program for American Indians with Metabolic Syndrome: The Balance Study

    Science.gov (United States)

    Lee, Elisa T.; Jobe, Jared B.; Yeh, Jeunliang; Ali, Tauqeer; Rhoades, Everett R.; Knehans, Allen W.; Willis, Diane J.; Johnson, Melanie R.; Zhang, Ying; Poolaw, Bryce; Rogers, Billy

    2012-01-01

    The Balance Study is a randomized controlled trial designed to reduce cardiovascular disease (CVD) risk in 200 American Indian (AI) participants with metabolic syndrome who reside in southwestern Oklahoma. Major risk factors targeted include weight, diet, and physical activity. Participants are assigned randomly to one of two groups, a guided or a…

  2. Longitudinal HIV Risk Behavior among the Drug Abuse Treatment Outcome Studies (DATOS) Adult Sample

    Science.gov (United States)

    Murphy, Debra A.; Brecht, Mary-Lynn; Herbeck, Diane; Evans, Elizabeth; Huang, David; Hser, Yih-Ing

    2008-01-01

    Longitudinal trajectories for HIV risk were examined over 5 years following treatment among 1,393 patients who participated in the nationwide Drug Abuse Treatment Outcome Studies. Both injection drug use and sexual risk behavior declined over time, with most of the decline occurring between intake and the first-year follow-up. However, results of…

  3. Ankylosing spondylitis confers substantially increased risk of clinical spine fractures : a nationwide case-control study

    NARCIS (Netherlands)

    Prieto-Alhambra, D; Muñoz-Ortego, J; De Vries, F; Vosse, D; Arden, N K; Bowness, P; Cooper, C; Diez-Perez, A; Vestergaard, P

    2015-01-01

    UNLABELLED: Ankylosing spondylitis (AS) leads to osteopenia/osteoporosis and spine rigidity. We conducted a case-control study and found that AS-affected patients have a 5-fold and 50 % increased risk of clinical spine and all clinical fractures, respectively. Excess risk of both is highest in the f

  4. Risk factors for Creutzfeldt-Jakob disease: a reanalysis of case-control studies.

    NARCIS (Netherlands)

    D.P.W.M. Wientjens (Dorothee); Z. Davanipour; K. Kondo; W.B. Matthews; R.G. Will (Robert); C.M. van Duijn (Cock); A. Hofman (Albert)

    1996-01-01

    textabstractTo review the evidence for risk factors of Creutzfeldt-Jakob disease (CJD), we pooled and reanalyzed the raw data of three case-control studies. The pooled data set comprised 178 patients and 333 control subjects. The strength of association between CJD and putative risk factors was asse

  5. Prospective study of falls and risk factors for falls in adults with advanced cancer.

    LENUS (Irish Health Repository)

    Stone, Carol A

    2012-06-10

    Retrospective studies of inpatients with cancer suggest that a cancer diagnosis confers a high risk of falls. In adults with advanced cancer, we aimed to prospectively document the incidence of falls, identify the risk factors, and determine if falls in this population occur predominantly in older patients.

  6. Positive Affect Processing and Joint Attention in Infants at High Risk for Autism: An Exploratory Study

    Science.gov (United States)

    Key, Alexandra P.; Ibanez, Lisa V.; Henderson, Heather A.; Warren, Zachary; Messinger, Daniel S.; Stone, Wendy L.

    2015-01-01

    Few behavioral indices of risk for autism spectrum disorders (ASD) are present before 12 months, and potential biomarkers remain largely unexamined. This prospective study of infant siblings of children with ASD (n = 16) and low-risk comparison infants (n = 15) examined group differences in event-related potentials (ERPs) indexing processing of…

  7. Individual and occupational risk factors for knee osteoarthritis – Study protocol of a case control study

    Directory of Open Access Journals (Sweden)

    Bouillon Bertil

    2008-02-01

    Full Text Available Abstract Background Knee osteoarthritis (OA is one of the frequent and functionally impairing disorders of the musculoskeletal system. In the literature, a number of occupational risk factors are discussed as being related to the development and progress of knee joint diseases, e.g. working in kneeling or squatting posture, lifting and carrying of heavy weights. The importance of the single risk factors and the possibility of prevention are currently under discussion. Besides the occupational factors, a number of individual risk factors are important, too. The distinction between work-related factors and individual factors is crucial in assessing the risk and in deriving preventive measures in occupational health. In existing studies, the occupational stress is determined mainly by surveys in employees and/or by making assumptions about individual occupations. Direct evaluation of occupational exposure has been performed only exceptionally. The aim of the research project ArGon is the assessment of different occupational factors in relation to individual factors (e.g. constitutional factors, leisure time activities, sports, which might influence the development and/or progression of knee (OA. The project is designed as a case control study. Methods/Design To raise valid data about the physical stress associated with occupational and leisure time activities, patients with and without knee OA are questioned by means of a standardised questionnaire and an interview. The required sample size was estimated to 800 cases and an equal number of controls. The degree and localisation of the knee cartilage or joint damages in the cases are documented on the basis of radiological, arthroscopic and/or operative findings in a patient record. Furthermore, occupational exposure is analysed at selected workplaces. To evaluate the answers provided in the questionnaire, work analysis is performed. Discussion In this research project, specific information on the

  8. Estudo comparativo do ciclo evolutivo de Rhodnius neglectus alimentados em pombos ou camundongos

    Directory of Open Access Journals (Sweden)

    Liléia Diotaiuti

    1987-06-01

    Full Text Available Baseados no encontro de 77,2% de reação de precipitina positiva para soro antiave de R. neglectus capturados em palmeiras da periferia de Belo Horizonte, estudamos o ciclo evolutivo de uma colonia recém-estabelecida no laboratório alimentada com sangue de pombo ou camundongo, na expectativa de demonstrarmos maior adaptação deste triatomíneo ao sangue da ave. Para comparação, estudamos o ciclo evolutivo destes insetos numa colônia há muito mantida em insetário. Nossos resultados mostram um desenvolvimento mais rápido da colônia recém- estabelecida, assim como do lote de triatomíneos alimentado em camundongo. Esses achados sugerem menor potencial biológico para triatomíneos criados por longo tempo em insetário em comparação a novas colônias. Sendo as aves os principais habitantes das palmeiras, a aparente preferência alimentar por sangue de aves demonstrada pela reação de precipitina parece ser circunstancial e não seletiva na busca do sangue com o qual o triatomíneo obteria melhor desenvolvimento.Feeding pattems of R. neglectus collected in palm trees around Belo Horizonte (Minas Gerais, Brazil were investigated. Precipitin tests showed 77.2% of avian blood. In view of these results, a new colony of R. neglectus established in the laboratory was fed regularly on pigeons or mice, in order to verify a possible better adaptation of this insect to the avian blood. As a control group a colony of R neglectus which has been maintained for several years in the laboratory was also observed. The results show a better development of the “new" colony in comparison with the old one, and of those bugs nourished with mice blood. Such findings suggest a poorer biological potential for triatomines maintained for long time in artificial conditions, in comparison with those living in the natural environment. As birds are the main vertebrate inhabitants of palm trees (the natural ecotope of R neglectus, the apparent feeding preference of

  9. Tipos de hogar, ciclo de vida familiar y pobreza en Costa Rica 1987-2002

    Directory of Open Access Journals (Sweden)

    Jorge A. Barquero B.

    2004-01-01

    Full Text Available El propósito de este estudio fue el de explorar las condiciones de vulnerabilidad sociodemográfica en Costa Rica, a partir del análisis de los cambios en los tipos de hogar y el ciclo de vida de las familias en condiciones de pobreza, mediante la utilización de información de las encuestas de hogares de 1987, 1994 y 2002. Los principales hallazgos revelan modificaciones importantes en la estructura y composición de los hogares y familias en el periodo de estudio, asociado a cambios en la dinámica sociodemográfica de la sociedad costarricense. La evolución en la incidencia de la pobreza por tipo de hogar, muestra que ésta es mayor entre los hogares nucleares que cuentan con hijos y al convertirse en monoparentales. La incidencia es más alta en 1987, se reduce para 1994 y prácticamente se mantiene para el 2002. No obstante que en todas las fases del ciclo de vida familiar la incidencia de la pobreza disminuyó en el periodo 1987-1994, en el periodo más reciente al 2002 la incidencia es mayor en las etapas en que las familias poseen más hijos dependientes menores de 18 años, lo que expone a estas familias a una mayor vulnerabilidad a situaciones de pobreza. Los hogares y familias con mayor riesgo de vulnerabilidad ante la pobreza, se hallaron entre aquellos con mayor cantidad de miembros dependientes menores de edad y jefeados por mujeres. No se encontraron evidencias significativas para afirmar que el estancamiento observado en los niveles de pobreza en el país hasta el 2002, fuese producto de los cambios encontrados en los patrones familiares, aunque ciertamente se hace necesario profundizar el análisis de las interrelaciones entre pobreza y cambios demográficos.

  10. The burden of cancer risk in Canada's indigenous population: a comparative study of known risks in a Canadian region

    Directory of Open Access Journals (Sweden)

    Elias B

    2011-10-01

    Full Text Available Brenda Elias1, Erich V Kliewer1–3, Madelyn Hall1, Alain A Demers1,2, Donna Turner1,2, Patricia Martens1, Say P Hong1, Lyna Hart4, Caroline Chartrand5, Garry Munro41Faculty of Medicine, Department of Community Health Sciences, University of Manitoba, Winnipeg, MB, Canada; 2CancerCare Manitoba, Winnipeg, MB, Canada; 3British Columbia Cancer Agency, Vancouver, BC, Canada; 4Assembly of Manitoba Chiefs Health Information Research Governance Committee, Winnipeg, MB, Canada; 5Manitoba First Nations Diabetes Integration Project, Winnipeg, MB, CanadaBackground: Canadian First Nations, the largest of the Aboriginal groups in Canada, have had lower cancer incidence and mortality rates than non-Aboriginal populations in the past. This pattern is changing with increased life expectancy, a growing population, and a poor social environment that influences risk behaviors, metabolic conditions, and disparities in screening uptake. These factors alone do not fully explain differences in cancer risk between populations, as genetic susceptibility and environmental factors also have significant influence. However, genetics and environment are difficult to modify. This study compared modifiable behavioral risk factors and metabolic-associated conditions for men and women, and cancer screening practices of women, between First Nations living on-reserve and a non-First Nations Manitoba rural population (Canada.Methods: The study used data from the Canadian Community Health Survey and the Manitoba First Nations Regional Longitudinal Health Survey to examine smoking, binge drinking, metabolic conditions, physical activity, fruit/vegetable consumption, and cancer-screening practices.Results: First Nations on-reserve had significantly higher rates of smoking (P < 0.001, binge drinking (P < 0.001, obesity (P < 0.001 and diabetes (P < 0.001, and less leisure-time physical activity (P = 0.029, and consumption of fruits and vegetables (P < 0.001. Sex differences were also

  11. Determinants of resilience to cigarette smoking among young Australians at risk: an exploratory study

    OpenAIRE

    Mikocka-Walus Antonina A; Turnbull Deborah A; Colgan Yola; Delfabbro Paul

    2010-01-01

    Abstract Background Numerous researchers studied risk factors associated with smoking uptake, however, few examined protective factors associated with smoking resilience. This study therefore aims to explore determinants of smoking resilience among young people from lower socioeconomic backgrounds who are at risk of smoking. Methods Overall, 92 out of 92 vocational education students accepted invitation to participate in this exploratory study. The Adelaide Technical and Further Education (TA...

  12. Risk factors for dementia in the epidemiological study of Munguialde County (Basque Country-Spain

    Directory of Open Access Journals (Sweden)

    Gordejuela Menocal María

    2008-10-01

    Full Text Available Abstract Background Prevalence of degenerative dementias and dementias associated with cerebrovascular disease is increasing. Dementia is one of the most significant public health problem. In recent years, the role of vascular risk factors (hypertension, diabetes mellitus and hypercholesterolemia and depression has been evaluated. The incidence of dementia and risk factors has not been fully investigated in Spain. The aim of this study was to identify the risk factors for dementia, Alzheimer's disease (AD and vascular dementia (VD in elderly people in Munguialde County (Spain. Methods A two phase, door-to-door populational study was performed. Demographic variables and the presence of vascular risk factors and depression were recorded. The MMSE, the DSM-IV and the conventional criteria for AD and VD were used in the evaluation. The odds ratio for each risk factor was calculated by logistic regression analysis. Results 1756 healthy subjects and 175 patients with dementia participated in the study. Of these, 133 had AD, 15 VD and the remainder other dementias. The risk factors for dementia and AD were female sex (OR = 1.67 and 1.97, respectively; age (OR = 1.14 and 1.15; stroke (OR = 7.84 and 3; and depression (OR = 53.08 and 3.19. Stroke was the only risk factor for VD (OR = 119. Conclusion Greater age, female sex, stroke and depression increase the risk of suffering dementia, AD and VD. The relationship between depression, vascular risk factors and dementia has clear public health implications. Prevention and early treatment of vascular risk factors and depression may have an important impact in lowering the risk of dementia and could modify the natural history of the disease.

  13. Por uma Didáctica de Línguas Estrangeiras no 1º Ciclo do Ensino Básico

    Directory of Open Access Journals (Sweden)

    Mário Cruz

    2009-11-01

    Full Text Available Desde da introdução no ano de 2005 das Línguas Estrangeiras no 1º Ciclo do Ensino Básico, muito se temvindo a trabalhar, no sentido de criar mais materiais didácticos e essencialmente em formar cada vez maisos nossos professores de Língua Estrangeira. No entanto, há ainda um longo caminho a percorrer no quese refere à criação duma didáctica de línguas estrangeiras no 1º Ciclo do Ensino Básico.Neste artigo, procuraremos discutir métodos e estratégias de ensino mais ligados à aprendizagem precocede línguas estrangeiras, tendo em atenção que “when learning is active, students do most of thework” (Silberman, 1996.

  14. ETAPAS DEL CICLO DE VIDA EN EL DESARROLLO DEL TURISMO RELIGIOSO: UNA COMPARACIÓN DE ESTUDIOS DE CASO

    Directory of Open Access Journals (Sweden)

    Genoveva Millán Vázquez de la Torre

    2012-01-01

    Full Text Available El turismo religioso es una opción estratégica de desarrollo para muchos destinos. Requiere orientación al turismo, importante inversión de capital privado y público, y predisposición de las autoridades eclesiásticas para adaptarse a las necesidades del visitante. Este artículo examina el turismo religioso de carácter católico en distintos lugares de México y Europa y valora implicaciones relacionadas con el ciclo de vida. Finalmente, se hacen recomendaciones para desarrollar el potencial de los lugares analizados, y para el avance del concepto de ciclo de vida de destinos turísticos religiosos.

  15. [Growing up under adversity in Germany : Design and methods of a developmental study on risk and protective mechanisms in families with diverse psychosocial risk].

    Science.gov (United States)

    Zimmermann, Peter; Vierhaus, Marc; Eickhorst, Andreas; Sann, Alexandra; Egger, Carine; Förthner, Judith; Gerlach, Jennifer; Iwanski, Alexandra; Liel, Christoph; Podewski, Fritz; Wyrwich, Sandra; Spangler, Gottfried

    2016-10-01

    Family adversity comprises many risk factors for parents and children. The German early intervention approach Frühe Hilfen aims at providing enduring, effective, and scientifically validated prevention and intervention for effective child protection against those risks. The study on risk and protective mechanisms in the development of families with diverse psychosocial risks aims at identifying those mechanisms that cause and stabilize or moderate and diminish maltreatment and neglect, as well as cognitive, social, and emotional developmental deviations in risk families, specifically in the current German social and child protection system. The study examines the development of competence and early behavior problems in a sample of infants and toddlers and the interaction quality with their caregivers by applying a longitudinal sequential-cohort design. The assessments include developmental tests, systematic observations, and questionnaire data. First results suggest stable risk group membership and moderate stability of single risk factors.

  16. Coffee Consumption and Risk of Gastric Cancer: A Large Updated Meta-Analysis of Prospective Studies

    Directory of Open Access Journals (Sweden)

    Feiyue Xie

    2014-09-01

    Full Text Available The potential role of coffee consumption in the development of various types of cancer has been extensively investigated in epidemiologic studies. How coffee consumption may modulate risk of gastric cancer, however, remains a subject open for investigation. To better quantify this relation, we quantitatively summarized evidence from prospective studies. Eligible studies were identified on PubMed and Embase databases. The summary risk estimates were obtained using the random-effects model. Subgroup, sensitivity and dose-response analyses were conducted. The present meta-analysis included 12 prospective cohort studies. A pooled analysis of these studies suggested that coffee consumption (highest vs. lowest consumption was not associated with risk of gastric cancer (RR = 1.12, 95% CI = 0.93–1.36. In the subgroup analysis, significant increased risk was detected in the U.S. studies (RR = 1.36, 95% CI = 1.06–1.74 and in the studies with <10 years of follow-up (RR = 1.24, 95% CI = 1.00–1.54, and the greatest increase in risk was observed in those studies without adjustment for smoking (RR = 1.48, 95% CI = 1.13–1.93. There was some evidence of publication bias (P for Egger’s test = 0.03. Cumulative evidence from prospective studies suggests that coffee consumption is not associated with risk of gastric cancer. The observed positive results may be confounded by smoking and need further investigation.

  17. High body mass index and cancer risk-a Mendelian randomisation study

    DEFF Research Database (Denmark)

    Benn, Marianne; Tybjærg-Hansen, Anne; Smith, George Davey;

    2016-01-01

    108,812 individuals from the general population, we found that observationally high BMI was associated with lower risk of lung and skin cancer overall and with higher risk of breast cancer in postmenopausal women, but not with other types of cancer. BMI increasing alleles were not associated with risk...... of follow-up (range 0-37), 8002 developed non-skin cancer, 3347 non-melanoma skin cancer, 1396 lung cancer, 637 other smoking related cancers, 1203 colon cancer, 159 kidney cancer, 1402 breast cancer, 1062 prostate cancer, and 2804 other cancers. Participants were genotyped for five genetic variants...... associated with BMI. Two Danish general population studies, the Copenhagen General Population and the Copenhagen City Heart Study. In observational analyses, overall risk of non-melanoma skin cancer was 35 % (95 % confidence interval 28-42 %) lower and risk of lung cancer 32 % (19-43 %) lower in individuals...

  18. La evolución del Ciclo Superior de Administración y finanzas, y su adaptación a la actualidad empresarial

    OpenAIRE

    Moro-Guijarro, Marta María

    2012-01-01

    En este trabajo se realiza el análisis del cambio curricular del Ciclo Superior LOGSE de Administración y Finanzas a Ciclo LOE, partiendo de su evolución previa y de su situación actual, con el fin de valorar si las modificaciones que presenta son más adecuadas a las necesidades actuales de la empresa y pueden favorecer la introducción de sus titulados en el mercado laboral.

  19. Configuración de los ciclos femenino-masculino, diurnonocturno y vida-memoria en La muerte de Artemio Cruz, de Carlos Fuentes

    OpenAIRE

    Edith González-Estrada

    2014-01-01

    El presente artículo pretende dar cuenta de la configuración de algunos ciclos de la vidamemoria del personaje central de la novela La muerte de Artemio Cruz, de Carlos Fuentes, y con ello analizar la configuración de las figuras femeninas-masculinas, así como los ciclos diurnos y nocturnos que se entrelazan para formar parte de su vida-memoria.

  20. Niveles de progesterona durante el ciclo normal y silencioso en bovinos en el trópico colombiano

    Directory of Open Access Journals (Sweden)

    Henry Grajales L

    2010-08-01

    Full Text Available Objetivo. Determinar la secuencia de cambios en los niveles de progesterona (NP durante el Ciclo Normal (CN y Ciclo Silencioso (CS. Materiales y métodos. 94 Hembras de los grupos raciales Holstein x Cebú (HC, Simmental x Cebú (SC, Romosinuano (R y Cebú (C se estudiaron desde la pubertad y durante los tres primeros ciclos estrales. Se tomaron muestras de sangre para determinar las concentraciones de progesterona mediante Radioinmunoanálisis, se determinaron 184 perfiles de progesterona para CN y 153 para CS. Para el análisis de la información se utilizó el programa estadístico SAS. Resultados. El grupo R presenta un patrón de variaciones de los NP a través de las fases del CN que tienediferencias significativas con el comportamiento de los NP en las fases del CN de los grupos SC, HC y C. Los niveles de progesterona en cada fase del CS coinciden con una fase luteal con bajos niveles de progesterona. Solo se encontraron diferencias significativas en la fase luteal tardía al comparar el CN con el CS, sin embargo se presentan diferencias numéricas en todas las fases entre estos dos tipos de ciclos. Conclusiones. Las concentraciones de progesterona tienen un marcado efecto sobre la presentación del CS, no obstante es difícil definir una concentración de progesterona que caracterice cada evento (CN o CS, sin embargo, es evidente que la progesterona influye sobre las probabilidades para que se de una respuesta reproductiva favorable o desfavorable.

  1. Risk factors for patellar tendinopathy in basketball and volleyball players: a cross-sectional study.

    Science.gov (United States)

    van der Worp, H; van Ark, M; Zwerver, J; van den Akker-Scheek, I

    2012-12-01

    Patellar tendinopathy (PT) has a multifactorial etiology, and many possible risk factors have been described in the literature. The findings are conflicting, though, and most research has been conducted on elite athletes. The aim of the current study is to determine the risk factors for PT in a large representative sample of basketball and volleyball players. Separate risk factors for men and women, basketball and volleyball players, and athletes with unilateral and bilateral PT were identified. All basketball and volleyball players between ages 18 and 35 from the Dutch Basketball Association and the Dutch Volleyball Association were invited to complete an online questionnaire on knee complaints and risk factors for PT. The logistic regression analyses included 2224 subjects. The risk factors for PT were age, playing at the national level, being male and playing volleyball (compared with playing basketball). The risk factors for men and women were comparable. Among volleyball players, outside hitters and middle blockers/hitters had an increased risk compared with setters. For basketball players, no risk factors could be identified. No differences in the risk factors were found between athletes with unilateral and bilateral PT. These findings should be taken into account for prevention and rehabilitation purposes.

  2. Serum Lipids and the Risk of Gastrointestinal Malignancies in the Swedish AMORIS Study

    Directory of Open Access Journals (Sweden)

    Wahyu Wulaningsih

    2012-01-01

    Full Text Available Background. Metabolic syndrome has been linked to an increased cancer risk, but the role of dyslipidaemia in gastrointestinal malignancies is unclear. We aimed to assess the risk of oesophageal, stomach, colon, and rectal cancers using serum levels of lipid components. Methods. From the Swedish Apolipoprotein Mortality Risk (AMORIS study, we selected 540,309 participants (> 20 years old with baseline measurements of total cholesterol (TC, triglycerides (TG, and glucose of whom 84,774 had baseline LDL cholesterol (LDL, HDL cholesterol (HDL, apolipoprotein B (apoB, and apolipoprotein A-I (apoA-I. Multivariate Cox proportional hazards regression was used to assess glucose and lipid components in relation to oesophageal, stomach, colon, and rectal cancer risk. Results. An increased risk of oesophageal cancer was observed in persons with high TG (e.g. HR: 2.29 (95% CI: 1.42–3.68 for the 4th quartile compared to the 1st and low LDL, LDL/HDL ratio, TC/HDL ratio, log (TG/HDL, and apoB/apoA-I ratio. High glucose and TG were linked with an increased colon cancer risk, while high TC levels were associated with an increased rectal cancer risk. Conclusion. The persistent link between TC and rectal cancer risk as well as between TG and oesophageal and colon cancer risk in normoglycaemic individuals may imply their substantiality in gastrointestinal carcinogenesis.

  3. Prevention of suicide and attempted suicide in Denmark. Epidemiological studies of suicide and intervention studies in selected risk groups

    DEFF Research Database (Denmark)

    Nordentoft, Merete

    2007-01-01

    percent as previously accepted, but lower. Risk factors for suicide among patients with schizophrenia were evaluated in case control studies, in nested case control studies, and in prospective studies. The following risk factors were the most important and frequently observed predictors: male gender...... patients in the integrated treatment. There were four suicides and one probable suicide (drowning) in standard treatment and one suicide in integrated treatment at two-year follow-up, but the study did not have sufficient power to detect these differences in proportion to who committed suicide; more than......-up of persons who attempted suicide. It was concluded that the risk of repetition in short- and medium-term follow-up studies was approximately 16 percent, with lower risk among "first-evers" compared to repeaters. There was a large variation in repetition rate. The proportion who committed suicide in medium...

  4. Information security risk management for computerized health information systems in hospitals: a case study of Iran

    Directory of Open Access Journals (Sweden)

    Zarei J

    2016-05-01

    Full Text Available Javad Zarei,1 Farahnaz Sadoughi2 1Health Information Management, Health Management and Economics Research Center, School of Health Management and Information Science, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran, 2Health Information Management Department, School of Health Management and Information Science, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran Background: In recent years, hospitals in Iran – similar to those in other countries – have experienced growing use of computerized health information systems (CHISs, which play a significant role in the operations of hospitals. But, the major challenge of CHIS use is information security. This study attempts to evaluate CHIS information security risk management at hospitals of Iran.Materials and methods: This applied study is a descriptive and cross-sectional research that has been conducted in 2015. The data were collected from 551 hospitals of Iran. Based on literature review, experts’ opinion, and observations at five hospitals, our intensive questionnaire was designed to assess security risk management for CHISs at the concerned hospitals, which was then sent to all hospitals in Iran by the Ministry of Health.Results: Sixty-nine percent of the studied hospitals pursue information security policies and procedures in conformity with Iran Hospitals Accreditation Standards. At some hospitals, risk identification, risk evaluation, and risk estimation, as well as risk treatment, are unstructured without any specified approach or methodology. There is no significant structured approach to risk management at the studied hospitals.Conclusion: Information security risk management is not followed by Iran’s hospitals and their information security policies. This problem can cause a large number of challenges for their CHIS security in future. Therefore, Iran’s Ministry of Health should develop practical policies to improve information security

  5. Life cycle analysis as a tool for assessing new waste water treatment systems. A case study of textile industry effluent; Analisis del ciclo de vida como herramienta de evaluacion de nuevos sistemas de depuracion de aguas residulaes. Caso practico: efluentes de la industria textil

    Energy Technology Data Exchange (ETDEWEB)

    Hospido, A.; Novo, E.; Moreira, M. T.; Feijoo, G.

    2001-07-01

    Life cycle analysis (LCA) is a technique that analyses the life cycle of a product process or activity in an attempt to identify its overall environmental impact. This approach can be of great help in strategic or operational decision-making in industry or business. This article takes as an example a comparative study of systems for treating strongly coloured industrial effluent. To this end, two well established technologies for dealing with industrial waste were examined: a) the physico-chemical treatment of effluents by coagulation-flocculation: b) a process combining physico-chemical treatment and biological aerobic activated sludge treatment. In addition, the viability of an emerging technology based on the decolouring of effluents with ligninolytic fungi was considered, although this process is still at the study stage. (Author) 13 refs.

  6. Variações do ciclo anual da temperatura da superfície do mar no pacífico tropical Annual cycle variations of sea surface temperature in the tropical pacific

    Directory of Open Access Journals (Sweden)

    Renato Orrú Pedroso Gerólamo

    2010-06-01

    Full Text Available Variações do ciclo anual da Temperatura da Superfície do Mar (TSM do Pacífico Tropical entre 20ºN e 20ºS, para o período de 1854 a 2006, foram estudadas usando análises de ondaletas. O estudo mostrou que o ciclo anual, considerando-se a variância para em torno de 1 ano, de TSM possui variabilidade interanual e interdecenal. Existem indicações de que a maior parte das variações interanuais no ciclo anual de TSM das áreas do hemisfério Norte (HN e do hemisfério Sul (HS, está relacionada ao ciclo do El Niño-Oscilação Sul (ENOS. A maioria dos picos da Média por Escalas da Potência localizada da ondaleta (MEPO para a escala entre 0,7 e 1,2 anos, para as áreas de ambos os hemisférios, coincide com extremos do ENOS. Os Espectros da Potência Global (EPGs mostraram variância máxima do ciclo anual de TSM entre 120ºE e 140ºE na faixa do HN (entre equador e 20ºN, e variância crescente da linha da data para leste com o máximo entre 100ºW e 80ºW na faixa do HS (entre equador e 20ºS. Portanto, o ciclo anual de TSM apresenta variações entre os HN e HS com a máxima variância localizando-se no hemisfério leste para o HN e no hemisfério oeste para o HS.Annual cycle variations of the sea surface temperature (SST in the Tropical Pacific Ocean between 20ºN and 20ºS for the period from 1854 to 2006 were studied using wavelet analysis. The study showed that the SST annual cycle, considered the variance around 1 year, contains interannual and interdecadal variabilities. There are indications that most of the SST annual cycle variations at Northern Hemisphere (NH and at Southern Hemisphere (SH areas is related to the El Niño-Southern Oscillation (ENSO cycle. Most peaks of the localized Scale Average Power (SAP for the 0.7-1.2 year scale for the areas on both hemispheres coincides with ENSO extremes. The Wavelet Power Spectra (WPS shows maximum variance of the SST annual cycle between 120ºE and 140ºE for the northern

  7. Monitoramento do ciclo estral de cutias (Dasyprocta leporina Lichtenstein, 1823 através de citologia esfoliativa vaginal e ultrassonografia

    Directory of Open Access Journals (Sweden)

    Lívia B. Campos

    2015-02-01

    Full Text Available O objetivo deste estudo foi monitorar o ciclo estral em cutias (Dasyprocta leporina criadas em cativeiro no semiárido brasileiro. Durante 70 dias, cinco cutias foram diariamente submetidas a citologia esfoliativa vaginal, e o monitoramento ultrassonográfico ovariano foi realizado a cada três dias. Um total de 8 ciclos estrais foi completamente monitorado, com duração de 28,2±0,7 dias, variando de 24 a 31 dias. Pela citologia esfoliativa vaginal, houve uma predominância de células superficiais nas fases de proestro e estro (P0,05. Os folículos foram identificados durante as fases estrogênicas (proestro e estro, com diâmetro médio de 1±0,5mm. Em apenas 12,5% das fases luteais, corpos lúteos medindo 1,4±0,9mm foram identificados. Conclui-se que a associação da citologia vaginal e da ultrassonografia ovariana constitui uma alternativa viável para o monitoramento de ciclos estrais e identificação das fases estrogênicas em cutias da espécie Dasyprocta leporina

  8. ESTUDO DO PRIMEIRO CICLO PRODUTIVO DA BANANEIRA `NANICÃO' (Musa sp. DESENVOLVIDA A PARTIR DE DIFERENTES TIPOS DE MUDA

    Directory of Open Access Journals (Sweden)

    SCARPARE FILHO J.A.

    1998-01-01

    Full Text Available Para avaliar o primeiro ciclo produtivo de bananeira `Nanicão' foram utilizados 5 tipos de muda: "chifrinho" e "chifrão" (brotações laterais com folhas lanceoladas, "guarda-chuva" (brotações separadas da planta mãe, com folhas normais, pedaços de rizoma e mudas micropropagadas. Foram avaliados o peso dos cachos, o número de pencas, o número de frutos por cacho e número de dias decorridos do plantio até a colheita. Os melhores desempenhos foram obtidos com as mudas "chifrinho" e "chifrão", que apresentaram maior equilíbrio das variáveis estudadas. As mudas constituidas de pedaços de rizoma, embora com uma produção alta, mostraram-se tardias no primeiro ciclo. O pior desempenho foi verificado nas mudas micropropagadas, com produções inferiores aos demais tratamentos, apresentando primeiro ciclo tardio e alta taxa de variação somaclonal.

  9. Processed food consumption and risk of esophageal squamous cell carcinoma: A case-control study in a high risk area.

    Science.gov (United States)

    Song, Qingkun; Wang, Xiaorong; Yu, Ignatius Tak-sun; Huang, Chengyu; Zhou, Xiaoqiao; Li, Jun; Wang, Dong

    2012-11-01

    This study was conducted to investigate the association between consumption of processed foods and esophageal cancer risk. A population-based case-control study was designed. For the present study, 254 patients with esophageal squamous cell carcinoma with pathological diagnoses were selected from Yanting during 2008 and 2010 and 254 community-based controls were selected from the same area, individually matched with cases by age and sex. Data on demographic, lifestyle and dietary factors were collected using food frequency questionnaires. A conditional logistic regression model was used to estimate the odds ratio (OR) with adjustments for potential confounders. Compared to the frequency of 3 times/week of preserved vegetables had a significant association with esophageal cancer (OR = 5.01, 95% confidence interval [CI] 2.07, 12.17). In stratified analyses, the OR of increasing intake of preserved vegetables for esophageal cancer were 2.02 in men (95% CI 1.18, 3.48), 3.15 in women (95% CI 1.28, 7.75), 2.41 (95% CI 1.45 4.01) in the persons <65 years old and 1.28 (95% CI 0.35, 4.65) in persons ≥65 years old. Consumption of pickled vegetables was not associated significantly with esophageal cancer risk. Intake of salted meat with a frequency of ≥1 time/week meant that the OR increased to 2.57 (95%CI 1.02, 6.43), but no significant trend or association in subgroup analysis was observed. Preserved vegetable consumption was associated with increased risk of esophageal cancer, while no association was found with pickled vegetables.

  10. Maternal autoantibody profiles at risk for autoimmune congenital heart block: a prospective study in high-risk patients

    Science.gov (United States)

    Tonello, Marta; Ruffatti, Amelia; Favaro, Maria; Tison, Tiziana; del Ross, Teresa; Calligaro, Antonia; Hoxha, Ariela; Mattia, Elena; Punzi, Leonardo

    2016-01-01

    Objective This prospective study aimed to identify antibody profiles characterising mothers with fetuses developing congenital heart block (CHB) by comparing their antibody frequencies and levels with those in unaffected mothers. Methods Eighty-one consecutive pregnant patients positive to anti-Ro±anti-La antibodies, at high risk of developing fetal CHB were prospectively studied. The 16 patients with fetal CHB outcome were considered the study population and the 65 patients with normal pregnancy outcomes were considered the control cohort. Anti-Ro52, anti-Ro60, anti-p200 and anti-La antibodies were assayed using home-made ELISA assays. Results The prevalence of anti-p200 antibodies was significantly higher in the fetal CHB affected patients than in the controls (p=0.03). Combinations of anti-p200 with anti-Ro52 and anti-Ro60 antibodies were significantly more frequent in the women with fetuses developing CHB than in the controls (p=0.03 for all combinations). The women with fetal CHB had significantly higher mean anti-Ro52, anti-Ro60 and anti-p200 levels than the controls (p=0.003, p=0.0001 and p=0.04, respectively); mean anti-La/SSB level was not significantly different in the two cohorts (p=0.25). Conclusions Since anti-p200, anti-Ro52 and anti-Ro60 antibodies, especially at high level, seem to identify patients at increased risk of developing fetal CHB, their detection could recognise anti-Ro/La positive women at risk for having an infant with this rare, potentially dangerous disorder. PMID:27026811

  11. Seroepidemiological Study of Brucellosis in High Risk Groups in Boyerahmad 1384

    Directory of Open Access Journals (Sweden)

    AM Khosravani

    2007-01-01

    Full Text Available ABSTRACT: Introduction & Objective: Brucellosis is a zoonotic disease that may have a major public health and economic impact in most countries. The disease appears as a Malt fever in humans and abortion in animals. This study was designed to determine the serologic titer of Brucella in high risk and non high risk people in Boyerahmad. Materials & Methods: A retrospective seroepidemiological study was performed on samples collected from 604 high risk and non high risk people using Rose Bengol test, tube standard test as a rapid test and 2 mercaptoethanol (2ME and comb's wright as a confirmatory test. The data collected were analyzed by X2 test via SPSS. Results: Seroprevalence of Brucellosis in high risk people appeared to be high in the Rose Bengal and tube standard test (TST 6.62 at titer ≥1/40 whereas for non high risk it was 0%. Confirmation test in high risk people was shown with 2ME in four people. Conclusion: Brucellosis is a major cause of disease in high risk people which can be due to direct or indirect contact with diary products of the related animals.

  12. Systematic Review of Studies of Workplace Exposure to Environmental Tobacco Smoke and Lung Cancer Risk

    Directory of Open Access Journals (Sweden)

    Xinzhuo WANG

    2011-04-01

    Full Text Available Background and objective It has been reported that there was a close relationship between lung cancer risk and environmental tobacco smoke at workplace. The aim of this study is to explore the relationship between workplace environmental tobacco smoke exposure and lung cancer risk among non-smoking subjects. Methods By searching Medline, CENTRAL (the Cochrane central register of controlledtrials, EMBASE, CBM, CNKI and VIP et al, we collected both domestic and overseas published documents on workplace environmental tobacco smoke exposure and lung cancer risk. Random or fixed effect models were applied to conduct systematic review on the study results, the combined odds ratio (OR and the 95% confidence interval (CI were calculated as well. Results 22 reports were included into the combined analysis, which indicated that 25% lung cancer risk was increased by exposing to workplace environment tobacco smoke (OR=1.25, 95%CI: 1.13-1.39, P < 0.001. For female the increased risk was 22% (OR=1.22, 95%CI: 1.05-1.42, P=0.011. For male the increased risk was 54%, but it does not reach the statistical significance (OR=1.54, 95%CI: 0.74-3.18, P=0.247. Conclusion Workplace environmental tobacco smoke exposure is an important risk factor of lung cancer risk among non-smoking subjects. Especially for non-smoking women who expose to workplace environment tobacco smoke have a close relationship with lung cancer.

  13. Bolivia: De la crisis económica al ciclo rebelde, 2000-2005

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    Darío I. Restrepo Botero

    2016-01-01

    Full Text Available El año de 1998 se recuerda por una crisis económica mundial que golpeó muy fuerte a Bolivia y socavó las bases económicas de la estabilidad política sobre la que se apoyó el neoliberalismo desde el año de 1986. El gobierno pretendió hacer pagar la crisis a los sectores populares, lo que desencadenó “el ciclo rebelde”, que derrotó primero en el 2000 la privatización trasnacional del agua, cercó las grandes ciudades varias veces en defensa de los sembrados de coca durante el primer lustro del siglo y reapropió para el Estado el servicio de gas en el año 2003. Al fragor de las luchas se construyó “la agenda de octubre”, que participó del conjunto de condiciones políticas necesarias para que las revueltas sociales se convirtieran en alternativa de poder, programa que llevaría a la victoria electoral de la presidencia de la república al indígena Evo Morales a finales del 2005.

  14. Ciclo de estudios de Ginebra. La industrialización de la construcción

    Directory of Open Access Journals (Sweden)

    Aguirre de Yraola, Fernando

    1965-05-01

    Full Text Available This article gives information about the program of research developed by the Working Group of the United Nations Economic Committee for Europe (Housing Committee for Building and Planning. It includes a summary of the documents collected by the Secretariat of the above Committee. The matters that are discussed can be included under the above headings: comparison of buildings costs; effects of repetition of operations at the working site; economy and technology of building upkeep; statistics of building mechanization, and modular standardization of building units.El presente artículo es una información referente al Ciclo de Estudios realizado por el Grupo de Trabajo de la Comisión Económica para Europa, de las Naciones Unidas (Comité de la Vivienda, de la Edificación y de la Planificación, y contiene una recopilación de las ideas tomadas de los documentos del Secretariado de dicha Comisión. Los problemas tratados pueden incluirse en la siguiente temática general: Comparación de los costos de la construcción; Efectos de la repetición sobre las operaciones de construcción en obra; Economía y técnica de la conservación de edificios; Estadística de la mecanización de la industria de la edificación, y Coordinación dimensional de elementos constructivos.

  15. El ambiente en un aula del ciclo de transición

    Directory of Open Access Journals (Sweden)

    Ana Polanco Hernández

    2004-01-01

    Full Text Available El artículo en su inicio expone la conceptualización que distintos pedagogos han asignado a través de la historia al ambiente físico en el jardín infantil. Luego se plantean características de tamaño, iluminación, decoración de paredes, mobiliario y la división por áreas de trabajo que puede poseer un aula del ciclo de transición, Se hace una descripción de cada área y el material didáctico que es recomendable que posean. cada una de ellas. Se propone las características del mobiliario, el cual debe adaptarse a no solo a las necesidades e intereses de los niños y niñas, si no también debe ser acorde con la metodología que se trabaje. Por último se comenta el papel de los materiales

  16. Envejecimiento saludable: perspectiva de género y de ciclo vital

    Directory of Open Access Journals (Sweden)

    Mª Pilar Montero-López

    2015-04-01

    Full Text Available Objetivo: Identificar factores bioculturales y sociales que actúan en diferentes etapas del ciclo vital, implicados en la forma de envejecer de mujeres y hombres mayores de 65 años. Material y Método: 213 personas; edad media 73.9 (std=5.8 en mujeres y 74.8 (std=6.6 en hombres. Datos recogidos en Centros Culturales y de Ocio de la Comunidad de Madrid. El envejecimiento saludable (a partir del número de enfermedades diagnosticadas, percepción de la salud, satisfacción con la vida y estado auditivo y bucal,fue considerado como variable dependiente. La edad, sexo, nivel de estudios, talla sentado, envergadura, edad de primera maternidad y número total de hijos fueron consideradas como variables independientes. Se utilizaron modelos de regresión lineal múltiple para analizar la relación de estas variables con la calidad del envejecimiento. Resultados: El envejecimiento saludable se asocia negativamente con edad y directamente con talla sentado en hombres. En mujeres el envejecimiento saludable se asocia positivamente con años de educación, cuando se incluye la edad de primera maternidad,ésta es la única variable con efecto significativo. Conclusiones: Existen diferentes factores que actúan a lo largo de la vida de los hombres y de las mujeres y que afectan de manera distinta a su forma de envejecer.

  17. Necessidades e preocupações dos pais em diferentes etapas do ciclo vital

    Directory of Open Access Journals (Sweden)

    Bárbara Tarouco da Silva

    2014-12-01

    Full Text Available Objetivo: identificar as necessidades e as preocupações prioritárias, manifestadas pelos pais no desempenho do seu papel, em três etapas do ciclo vital: adolescência, idade produtiva e idade madura. Metodologia: estudo exploratório com abordagem qualitativa, desenvolvido com quatorze pais residentes em um município no extremo sul do Brasil. Os dados foram coletados entre maio e agosto de 2011, por meio de entrevista em profundidade. Através da técnica da análise textual discursiva e da matriz construída com base na teoria bioecológica de Bronfenbrenner, foram construídas três categorias: Necessidades/preocupações do pai, geradas em sua relação com o mundo do trabalho; Necessidades/preocupações que emergem da relação de cuidado com os filhos e Preocupações dos pais com relação ao futuro dos filhos. Conclusão: identificou-se que a preocupação com o futuro dos filhos foi apontada por pais de todas as faixas-etárias investigadas.

  18. Revisión teórica del modelo de ciclo de vida organizacional

    Directory of Open Access Journals (Sweden)

    Laura Angélica Décaro Santiago

    2014-06-01

    Full Text Available Los Modelos de Ciclo de Vida Organizacional (OLC, por sus siglas en inglés tienen por objetivo representar el nivel de desarrollo de la empresa a través de una serie de etapas consecutivas; diferenciadas por características propias y retos por resolver. Los autores que se han dedicado al estudio del tema consideran que un buen entendimiento sobre el nivel de desarrollo de la empresa, permite tener un visión más amplia de las características y necesidades de la misma para con ello, auxiliar a la toma de decisiones y por ende, prepararse para los retos presentes y futuros. Desde su aparición, en los años 50´s, OLC ha sido abordado por un gran número de académicos, investigadores, consultores y asesores de empresas. En la literatura se muestran tres periodos de estudio; la conceptualización, la evidencia empírica y la aplicación de nuevas metodologías de investigación; así como el estudio de sujetos y subsistemas más específicos. Así bien, este documento describe los modelos más representativos, sus adaptaciones y aplicaciones a lo largo de estos tres periodos; generando así una investigación de alcance descriptivo.

  19. Evidencias del ciclo Pampeano en el basamento del sector noroccidental de la sierra de San Luis

    Directory of Open Access Journals (Sweden)

    GI Vujovich

    2003-12-01

    Full Text Available Se presenta una edad preliminar U-Pb sobre circones de un gneis biotítico feldespático perteneciente al Complejo Nogolí aflorante en las cercanías de San Francisco del Monte de Oro, sierra de San Luis. Los resultados indican una edad de cristalización para el mismo de 554 ± 4,8 Ma, representando un interesante hallazgo del ciclo Pampeano en el marco geológico considerado. Se postula además la existencia de un proceso de pérdida episódica de Pb durante el Cretácico inferior (112 ± 23 Ma, reflejado en la intersección inferior de la recta de discordia. Esta edad inferior podría asociarse con gradientes térmicos anómalos relacionados con los procesos distensivos generalizados que afectaron al Gondwana durante la apertura del océano Atlántico Sur.

  20. VTE Risk assessment – a prognostic Model: BATER Cohort Study of young women

    Directory of Open Access Journals (Sweden)

    Schürmann Rolf

    2005-04-01

    Full Text Available Abstract Background Community-based cohort studies are not available that evaluated the predictive power of both clinical and genetic risk factors for venous thromboembolism (VTE. There is, however, clinical need to forecast the likelihood of future occurrence of VTE, at least qualitatively, to support decisions about intensity of diagnostic or preventive measures. Materials and methods A 10-year observation period of the Bavarian Thromboembolic Risk (BATER study, a cohort study of 4337 women (18–55 years, was used to develop a predictive model of VTE based on clinical and genetic variables at baseline (1993. The objective was to prepare a probabilistic scheme that discriminates women with virtually no VTE risk from those at higher levels of absolute VTE risk in the foreseeable future. A multivariate analysis determined which variables at baseline were the best predictors of a future VTE event, provided a ranking according to the predictive power, and permitted to design a simple graphic scheme to assess the individual VTE risk using five predictor variables. Results Thirty-four new confirmed VTEs occurred during the observation period of over 32,000 women-years (WYs. A model was developed mainly based on clinical information (personal history of previous VTE and family history of VTE, age, BMI and one composite genetic risk markers (combining Factor V Leiden and Prothrombin G20210A Mutation. Four levels of increasing VTE risk were arbitrarily defined to map the prevalence in the study population: No/low risk of VTE (61.3%, moderate risk (21.1%, high risk (6.0%, very high risk of future VTE (0.9%. In 10.6% of the population the risk assessment was not possible due to lacking VTE cases. The average incidence rates for VTE in these four levels were: 4.1, 12.3, 47.2, and 170.5 per 104 WYs for no, moderate, high, and very high risk, respectively. Conclusion Our prognostic tool – containing clinical information (and if available also genetic data

  1. Alzheimer's Disease is an Important Risk Factor of Fractures: a Meta-analysis of Cohort Studies.

    Science.gov (United States)

    Liang, Ying; Wang, Lei

    2016-04-12

    The risk of fracture in individuals with Alzheimer's disease had not been fully quantified. A systematic review and meta-analysis of cohort studies was performed to estimate the impact of Alzheimer's disease on risk of fractures. Pubmed and Embase were searched for eligible cohort studies assessing the association between Alzheimer's disease and risk of fractures. The overall relative risks (RRs) with 95% CIs were calculated using a random-effects model to evaluate the association. Six cohort studies with a total of 137,986 participants were included into the meta-analysis. Meta-analysis of a total of six studies showed that Alzheimer's disease was significantly associated with two-fold increased risk of fractures (RR = 2.18, 95 % CI 1.64-2.90, P Alzheimer's disease was significantly associated with 2.5-fold increased risk of hip fracture (RR = 2.52, 95 % CI 2.26-2.81, P Alzheimer's disease is a risk factor of hip fracture.

  2. Allergic conditions and risk of hematological malignancies in adults: a cohort study

    Directory of Open Access Journals (Sweden)

    Schwartzbaum Judith

    2004-11-01

    Full Text Available Abstract Background Two contradictory hypotheses have been proposed to explain the relationship between allergic conditions and malignancies, the immune surveillance hypothesis and the antigenic stimulation hypothesis. The former advocates that allergic conditions may be protective against development of cancer, whereas the latter proposes an increased risk. This relationship has been studied in several case-control studies, but only in a few cohort studies. Methods The association between allergic conditions and risk of developing leukemia, Hodgkin's disease, non-Hodgkin's lymphoma and myeloma was investigated in a cohort of 16,539 Swedish twins born 1886–1925. Prospectively collected, self-reported information about allergic conditions such as asthma, hay fever or eczema was obtained through questionnaires administered in 1967. The cohort was followed 1969–99 and cancer incidence was ascertained from the Swedish Cancer Registry. Results Hives and asthma tended to increase the risk of leukemia (relative risk [RR] = 2.1, 95% Confidence Interval [CI] 1.0–4.5 and RR = 1.6, 95% CI 0.8–3.5, respectively. There was also an indication of an increased risk of non-Hodgkin's lymphoma associated with eczema during childhood (RR = 2.3, 95% CI 1.0–5.3. Conclusion In contrast to most previous studies, our results do not indicate a protective effect of allergic conditions on the risk of developing hematological malignancies. Rather, they suggest that allergic conditions might increase the risk of some hematological malignancies.

  3. NIH study finds that coffee drinkers have lower risk of death

    Science.gov (United States)

    Older adults who drank coffee -- caffeinated or decaffeinated -- had a lower risk of death overall than others who did not drink coffee, according a study by researchers from the National Cancer Institute (NCI), part of the National Institutes of Health,

  4. Autoimmune diseases and severe infections as risk factors for mood disorders a nationwide study

    DEFF Research Database (Denmark)

    Benros, Michael E.; Waltoft, Berit L.; Nordentoft, Merete;

    2013-01-01

    Mood disorders frequently co-occur with medical diseases that involve inflammatory pathophysiologic mechanisms. Immune responses can affect the brain and might increase the risk of mood disorders, but longitudinal studies of comorbidity are lacking....

  5. Association of energy and fat intake with prostate carcinoma risk: Results from the Netherlands Cohort Study

    NARCIS (Netherlands)

    Schuurman, A.G.; Brandt, P.A. van den; Dorant, E.; Brants, H.A.M.; Goldbohm, R.A.

    1999-01-01

    BACKGROUND. The roles of energy and fat intake as risk factors for prostate carcinoma are still questionable. Therefore, these factors were evaluated in the Netherlands Cohort Study described in this article.

  6. A risk assessment study on work-related musculoskeletal disorders among dentists in Bhopal, India

    Directory of Open Access Journals (Sweden)

    Chetna Batham

    2016-01-01

    Conclusion: This risk assessment study found that there is a high prevalence of MSDs and WMSDs among dentists. Ergonomic awareness and health promotion need to be integrated with the professional practice for dentists.

  7. Plasma Enterolignan Concentrations and Colorectal Cancer Risk in a Nested Case-Control Study

    NARCIS (Netherlands)

    Kuijsten, A.; Hollman, P.C.H.; Boshuizen, H.C.; Buijsman, M.N.C.P.; Veer, van 't P.; Kok, F.J.; Arts, I.C.W.; Bueno-de-Mesquita, H.B.

    2008-01-01

    Enterolignans are biphenolic compounds that possess several biologic activities whereby they may influence carcinogenesis. The authors investigated the association between plasma enterolactone and enterodiol and colorectal cancer risk in a Dutch prospective study. Among more than 35,000 participants

  8. Study Ties Some Migraines to Artery Tears in Neck, Raising Stroke Risk

    Science.gov (United States)

    ... Some Migraines to Artery Tears in Neck, Raising Stroke Risk Problem also more likely in men and ... arteries, which can increase the chances of a stroke, a new study suggests. Exactly what triggers these ...

  9. NIH study shows increased risk for two types of myotonic muscular dystrophy

    Science.gov (United States)

    Adults with a form of muscular dystrophy called myotonic muscular dystrophy (MMD) may be at increased risk of developing cancer, according to a study by investigators at the National Cancer Institute (NCI), part of the National Institutes of Health.

  10. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013

    NARCIS (Netherlands)

    Forouzanfar, Mohammad H; Alexander, Lily; Anderson, H Ross; Bachman, Victoria F; Biryukov, Stan; Brauer, Michael; Burnett, Richard; Casey, Daniel; Coates, Matthew M; Cohen, Aaron; Delwiche, Kristen; Estep, Kara; Frostad, Joseph J; Kc, Astha; Kyu, Hmwe H; Moradi-Lakeh, Maziar; Ng, Marie; Slepak, Erica Leigh; Thomas, Bernadette A; Wagner, Joseph; Aasvang, Gunn Marit; Abbafati, Cristiana; Ozgoren, Ayse Abbasoglu; Abd-Allah, Foad; Abera, Semaw F; Aboyans, Victor; Abraham, Biju; Abraham, Jerry Puthenpurakal; Abubakar, Ibrahim; Abu-Rmeileh, Niveen M E; Aburto, Tania C; Achoki, Tom; Adelekan, Ademola; Adofo, Koranteng; Adou, Arsène K; Adsuar, José C; Afshin, Ashkan; Agardh, Emilie E; Al Khabouri, Mazin J; Al Lami, Faris H; Alam, Sayed Saidul; Alasfoor, Deena; Albittar, Mohammed I; Alegretti, Miguel A; Aleman, Alicia V; Alemu, Zewdie A; Alfonso-Cristancho, Rafael; Alhabib, Samia; Ali, Raghib; Ali, Mohammed K; Alla, François; Allebeck, Peter; Allen, Peter J; Alsharif, Ubai; Alvarez, Elena; Alvis-Guzman, Nelson; Amankwaa, Adansi A; Amare, Azmeraw T; Ameh, Emmanuel A; Ameli, Omid; Amini, Heresh; Ammar, Walid; Anderson, Benjamin O; Antonio, Carl Abelardo T; Anwari, Palwasha; Cunningham, Solveig Argeseanu; Arnlöv, Johan; Arsenijevic, Valentina S Arsic; Artaman, Al; Asghar, Rana J; Assadi, Reza; Atkins, Lydia S; Atkinson, Charles; Avila, Marco A; Awuah, Baffour; Badawi, Alaa; Bahit, Maria C; Bakfalouni, Talal; Balakrishnan, Kalpana; Balalla, Shivanthi; Balu, Ravi Kumar; Banerjee, Amitava; Barber, Ryan M; Barker-Collo, Suzanne L; Barquera, Simon; Barregard, Lars; Barrero, Lope H; Barrientos-Gutierrez, Tonatiuh; Basto-Abreu, Ana C; Basu, Arindam; Basu, Sanjay; Basulaiman, Mohammed O; Ruvalcaba, Carolina Batis; Beardsley, Justin; Bedi, Neeraj; Bekele, Tolesa; Bell, Michelle L; Benjet, Corina; Bennett, Derrick A; Benzian, Habib; Bernabé, Eduardo; Beyene, Tariku J; Bhala, Neeraj; Bhalla, Ashish; Bhutta, Zulfiqar A; Bikbov, Boris; Abdulhak, Aref A Bin; Blore, Jed D; Blyth, Fiona M; Bohensky, Megan A; Başara, Berrak Bora; Borges, Guilherme; Bornstein, Natan M; Bose, Dipan; Boufous, Soufiane; Bourne, Rupert R; Brainin, Michael; Brazinova, Alexandra; Breitborde, Nicholas J; Brenner, Hermann; Briggs, Adam D M; Broday, David M; Brooks, Peter M; Bruce, Nigel G; Brugha, Traolach S; Brunekreef, Bert; Buchbinder, Rachelle; Bui, Linh N; Bukhman, Gene; Bulloch, Andrew G; Burch, Michael; Burney, Peter G J; Campos-Nonato, Ismael R; Campuzano, Julio C; Cantoral, Alejandra J; Caravanos, Jack; Cárdenas, Rosario; Cardis, Elisabeth; Carpenter, David O; Caso, Valeria; Castañeda-Orjuela, Carlos A; Castro, Ruben E; Catalá-López, Ferrán; Cavalleri, Fiorella; Çavlin, Alanur; Chadha, Vineet K; Chang, Jung-Chen; Charlson, Fiona J; Chen, Honglei; Chen, Wanqing; Chen, Zhengming; Chiang, Peggy P; Chimed-Ochir, Odgerel; Chowdhury, Rajiv; Christophi, Costas A; Chuang, Ting-Wu; Chugh, Sumeet S; Cirillo, Massimo; Claßen, Thomas Kd; Colistro, Valentina; Colomar, Mercedes; Colquhoun, Samantha M; Contreras, Alejandra G; Cooper, Cyrus; Cooperrider, Kimberly; Cooper, Leslie T; Coresh, Josef; Courville, Karen J; Criqui, Michael H; Cuevas-Nasu, Lucia; Damsere-Derry, James; Danawi, Hadi; Dandona, Lalit; Dandona, Rakhi; Dargan, Paul I; Davis, Adrian; Davitoiu, Dragos V; Dayama, Anand; de Castro, E Filipa; De la Cruz-Góngora, Vanessa; De Leo, Diego; de Lima, Graça; Degenhardt, Louisa; Del Pozo-Cruz, Borja; Dellavalle, Robert P; Deribe, Kebede; Derrett, Sarah; Jarlais, Don C Des; Dessalegn, Muluken; deVeber, Gabrielle A; Devries, Karen M; Dharmaratne, Samath D; Dherani, Mukesh K; Dicker, Daniel; Ding, Eric L; Dokova, Klara; Dorsey, E Ray; Driscoll, Tim R; Duan, Leilei; Durrani, Adnan M; Ebel, Beth E; Ellenbogen, Richard G; Elshrek, Yousef M; Endres, Matthias; Ermakov, Sergey P; Erskine, Holly E; Eshrati, Babak; Esteghamati, Alireza; Fahimi, Saman; Faraon, Emerito Jose A; Farzadfar, Farshad; Fay, Derek F J; Feigin, Valery L; Feigl, Andrea B; Fereshtehnejad, Seyed-Mohammad; Ferrari, Alize J; Ferri, Cleusa P; Flaxman, Abraham D; Fleming, Thomas D; Foigt, Nataliya; Foreman, Kyle J; Paleo, Urbano Fra; Franklin, Richard C; Gabbe, Belinda; Gaffikin, Lynne; Gakidou, Emmanuela; Gamkrelidze, Amiran; Gankpé, Fortuné G; Gansevoort, Ron T; García-Guerra, Francisco A; Gasana, Evariste; Geleijnse, Johanna M; Gessner, Bradford D; Gething, Pete; Gibney, Katherine B; Gillum, Richard F; Ginawi, Ibrahim A M; Giroud, Maurice; Giussani, Giorgia; Goenka, Shifalika; Goginashvili, Ketevan; Dantes, Hector Gomez; Gona, Philimon; de Cosio, Teresita Gonzalez; González-Castell, Dinorah; Gotay, Carolyn C; Goto, Atsushi; Gouda, Hebe N; Guerrant, Richard L; Gugnani, Harish C; Guillemin, Francis; Gunnell, David; Gupta, Rahul; Gupta, Rajeev; Gutiérrez, Reyna A; Hafezi-Nejad, Nima; Hagan, Holly; Hagstromer, Maria; Halasa, Yara A; Hamadeh, Randah R; Hammami, Mouhanad; Hankey, Graeme J; Hao, Yuantao; Harb, Hilda L; Haregu, Tilahun Nigatu; Haro, Josep Maria; Havmoeller, Rasmus; Hay, Simon I; Hedayati, Mohammad T; Heredia-Pi, Ileana B; Hernandez, Lucia; Heuton, Kyle R; Heydarpour, Pouria; Hijar, Martha; Hoek, Hans W; Hoffman, Howard J; Hornberger, John C; Hosgood, H Dean; Hoy, Damian G; Hsairi, Mohamed; Hu, Guoqing; Hu, Howard; Huang, Cheng; Huang, John J; Hubbell, Bryan J; Huiart, Laetitia; Husseini, Abdullatif; Iannarone, Marissa L; Iburg, Kim M; Idrisov, Bulat T; Ikeda, Nayu; Innos, Kaire; Inoue, Manami; Islami, Farhad; Ismayilova, Samaya; Jacobsen, Kathryn H; Jansen, Henrica A; Jarvis, Deborah L; Jassal, Simerjot K; Jauregui, Alejandra; Jayaraman, Sudha; Jeemon, Panniyammakal; Jensen, Paul N; Jha, Vivekanand; Jiang, Fan; Jiang, Guohong; Jiang, Ying; Jonas, Jost B; Juel, Knud; Kan, Haidong; Roseline, Sidibe S Kany; Karam, Nadim E; Karch, André; Karema, Corine K; Karthikeyan, Ganesan; Kaul, Anil; Kawakami, Norito; Kazi, Dhruv S; Kemp, Andrew H; Kengne, Andre P; Keren, Andre; Khader, Yousef S; Khalifa, Shams Eldin Ali Hassan; Khan, Ejaz A; Khang, Young-Ho; Khatibzadeh, Shahab; Khonelidze, Irma; Kieling, Christian; Kim, Daniel; Kim, Sungroul; Kim, Yunjin; Kimokoti, Ruth W; Kinfu, Yohannes; Kinge, Jonas M; Kissela, Brett M; Kivipelto, Miia; Knibbs, Luke D; Knudsen, Ann Kristin; Kokubo, Yoshihiro; Kose, M Rifat; Kosen, Soewarta; Kraemer, Alexander; Kravchenko, Michael; Krishnaswami, Sanjay; Kromhout, Hans; Ku, Tiffany; Defo, Barthelemy Kuate; Bicer, Burcu Kucuk; Kuipers, Ernst J; Kulkarni, Chanda; Kulkarni, Veena S; Kumar, G Anil; Kwan, Gene F; Lai, Taavi; Balaji, Arjun Lakshmana; Lalloo, Ratilal; Lallukka, Tea; Lam, Hilton; Lan, Qing; Lansingh, Van C; Larson, Heidi J; Larsson, Anders; Laryea, Dennis O; Lavados, Pablo M; Lawrynowicz, Alicia E; Leasher, Janet L; Lee, Jong-Tae; Leigh, James; Leung, Ricky; Levi, Miriam; Li, Yichong; Li, Yongmei; Liang, Juan; Liang, Xiaofeng; Lim, Stephen S; Lindsay, M Patrice; Lipshultz, Steven E; Liu, Shiwei; Liu, Yang; Lloyd, Belinda K; Logroscino, Giancarlo; London, Stephanie J; Lopez, Nancy; Lortet-Tieulent, Joannie; Lotufo, Paulo A; Lozano, Rafael; Lunevicius, Raimundas; Ma, Jixiang; Ma, Stefan; Machado, Vasco M P; MacIntyre, Michael F; Magis-Rodriguez, Carlos; Mahdi, Abbas A; Majdan, Marek; Malekzadeh, Reza; Mangalam, Srikanth; Mapoma, Christopher C; Marape, Marape; Marcenes, Wagner; Margolis, David J; Margono, Christopher; Marks, Guy B; Martin, Randall V; Marzan, Melvin B; Mashal, Mohammad T; Masiye, Felix; Mason-Jones, Amanda J; Matsushita, Kunihiro; Matzopoulos, Richard; Mayosi, Bongani M; Mazorodze, Tasara T; McKay, Abigail C; McKee, Martin; McLain, Abigail; Meaney, Peter A; Medina, Catalina; Mehndiratta, Man Mohan; Mejia-Rodriguez, Fabiola; Mekonnen, Wubegzier; Melaku, Yohannes A; Meltzer, Michele; Memish, Ziad A; Mendoza, Walter; Mensah, George A; Meretoja, Atte; Mhimbira, Francis Apolinary; Micha, Renata; Miller, Ted R; Mills, Edward J; Misganaw, Awoke; Mishra, Santosh; Ibrahim, Norlinah Mohamed; Mohammad, Karzan A; Mokdad, Ali H; Mola, Glen L; Monasta, Lorenzo; Hernandez, Julio C Montañez; Montico, Marcella; Moore, Ami R; Morawska, Lidia; Mori, Rintaro; Moschandreas, Joanna; Moturi, Wilkister N; Mozaffarian, Dariush; Mueller, Ulrich O; Mukaigawara, Mitsuru; Mullany, Erin C; Murthy, Kinnari S; Naghavi, Mohsen; Nahas, Ziad; Naheed, Aliya; Naidoo, Kovin S; Naldi, Luigi; Nand, Devina; Nangia, Vinay; Narayan, Km Venkat; Nash, Denis; Neal, Bruce; Nejjari, Chakib; Neupane, Sudan P; Newton, Charles R; Ngalesoni, Frida N; de Dieu Ngirabega, Jean; Nguyen, Grant; Nguyen, Nhung T; Nieuwenhuijsen, Mark J; Nisar, Muhammad I; Nogueira, José R; Nolla, Joan M; Nolte, Sandra; Norheim, Ole F; Norman, Rosana E; Norrving, Bo; Nyakarahuka, Luke; Oh, In-Hwan; Ohkubo, Takayoshi; Olusanya, Bolajoko O; Omer, Saad B; Opio, John Nelson; Orozco, Ricardo; Pagcatipunan, Rodolfo S; Pain, Amanda W; Pandian, Jeyaraj D; Panelo, Carlo Irwin A; Papachristou, Christina; Park, Eun-Kee; Parry, Charles D; Caicedo, Angel J Paternina; Patten, Scott B; Paul, Vinod K; Pavlin, Boris I; Pearce, Neil; Pedraza, Lilia S; Pedroza, Andrea; Stokic, Ljiljana Pejin; Pekericli, Ayfer; Pereira, David M; Perez-Padilla, Rogelio; Perez-Ruiz, Fernando; Perico, Norberto; Perry, Samuel A L; Pervaiz, Aslam; Pesudovs, Konrad; Peterson, Carrie B; Petzold, Max; Phillips, Michael R; Phua, Hwee Pin; Plass, Dietrich; Poenaru, Dan; Polanczyk, Guilherme V; Polinder, Suzanne; Pond, Constance D; Pope, C Arden; Pope, Daniel; Popova, Svetlana; Pourmalek, Farshad; Powles, John; Prabhakaran, Dorairaj; Prasad, Noela M; Qato, Dima M; Quezada, Amado D; Quistberg, D Alex A; Racapé, Lionel; Rafay, Anwar; Rahimi, Kazem; Rahimi-Movaghar, Vafa; Rahman, Sajjad Ur; Raju, Murugesan; Rakovac, Ivo; Rana, Saleem M; Rao, Mayuree; Razavi, Homie; Reddy, K Srinath; Refaat, Amany H; Rehm, Jürgen; Remuzzi, Giuseppe; Ribeiro, Antonio L; Riccio, Patricia M; Richardson, Lee; Riederer, Anne; Robinson, Margaret; Roca, Anna; Rodriguez, Alina; Rojas-Rueda, David; Romieu, Isabelle; Ronfani, Luca; Room, Robin; Roy, Nobhojit; Ruhago, George M; Rushton, Lesley; Sabin, Nsanzimana; Sacco, Ralph L; Saha, Sukanta; Sahathevan, Ramesh; Sahraian, Mohammad Ali; Salomon, Joshua A; Salvo, Deborah; Sampson, Uchechukwu K; Sanabria, Juan R; Sanchez, Luz Maria; Sánchez-Pimienta, Tania G; Sanchez-Riera, Lidia; Sandar, Logan; Santos, Itamar S; Sapkota, Amir; Satpathy, Maheswar; Saunders, James E; Sawhney, Monika; Saylan, Mete I; Scarborough, Peter; Schmidt, Jürgen C; Schneider, Ione J C; Schöttker, Ben; Schwebel, David C; Scott, James G; Seedat, Soraya; Sepanlou, Sadaf G; Serdar, Berrin; Servan-Mori, Edson E; Shaddick, Gavin; Shahraz, Saeid; Levy, Teresa Shamah; Shangguan, Siyi; She, Jun; Sheikhbahaei, Sara; Shibuya, Kenji; Shin, Hwashin H; Shinohara, Yukito; Shiri, Rahman; Shishani, Kawkab; Shiue, Ivy; Sigfusdottir, Inga D; Silberberg, Donald H; Simard, Edgar P; Sindi, Shireen; Singh, Abhishek; Singh, Gitanjali M; Singh, Jasvinder A; Skirbekk, Vegard; Sliwa, Karen; Soljak, Michael; Soneji, Samir; Søreide, Kjetil; Soshnikov, Sergey; Sposato, Luciano A; Sreeramareddy, Chandrashekhar T; Stapelberg, Nicolas J C; Stathopoulou, Vasiliki; Steckling, Nadine; Stein, Dan J; Stein, Murray B; Stephens, Natalie; Stöckl, Heidi; Straif, Kurt; Stroumpoulis, Konstantinos; Sturua, Lela; Sunguya, Bruno F; Swaminathan, Soumya; Swaroop, Mamta; Sykes, Bryan L; Tabb, Karen M; Takahashi, Ken; Talongwa, Roberto T; Tandon, Nikhil; Tanne, David; Tanner, Marcel; Tavakkoli, Mohammad; Te Ao, Braden J; Teixeira, Carolina M; Téllez Rojo, Martha M; Terkawi, Abdullah S; Texcalac-Sangrador, José Luis; Thackway, Sarah V; Thomson, Blake; Thorne-Lyman, Andrew L; Thrift, Amanda G; Thurston, George D; Tillmann, Taavi; Tobollik, Myriam; Tonelli, Marcello; Topouzis, Fotis; Towbin, Jeffrey A; Toyoshima, Hideaki; Traebert, Jefferson; Tran, Bach X; Trasande, Leonardo; Trillini, Matias; Trujillo, Ulises; Dimbuene, Zacharie Tsala; Tsilimbaris, Miltiadis; Tuzcu, Emin Murat; Uchendu, Uche S; Ukwaja, Kingsley N; Uzun, Selen B; van de Vijver, Steven; Van Dingenen, Rita; van Gool, Coen H; van Os, Jim; Varakin, Yuri Y; Vasankari, Tommi J; Vasconcelos, Ana Maria N; Vavilala, Monica S; Veerman, Lennert J; Velasquez-Melendez, Gustavo; Venketasubramanian, N; Vijayakumar, Lakshmi; Villalpando, Salvador; Violante, Francesco S; Vlassov, Vasiliy Victorovich; Vollset, Stein Emil; Wagner, Gregory R; Waller, Stephen G; Wallin, Mitchell T; Wan, Xia; Wang, Haidong; Wang, JianLi; Wang, Linhong; Wang, Wenzhi; Wang, Yanping; Warouw, Tati S; Watts, Charlotte H; Weichenthal, Scott; Weiderpass, Elisabete; Weintraub, Robert G; Werdecker, Andrea; Wessells, K Ryan; Westerman, Ronny; Whiteford, Harvey A; Wilkinson, James D; Williams, Hywel C; Williams, Thomas N; Woldeyohannes, Solomon M; Wolfe, Charles D A; Wong, John Q; Woolf, Anthony D; Wright, Jonathan L; Wurtz, Brittany; Xu, Gelin; Yan, Lijing L; Yang, Gonghuan; Yano, Yuichiro; Ye, Pengpeng; Yenesew, Muluken; Yentür, Gökalp K; Yip, Paul; Yonemoto, Naohiro; Yoon, Seok-Jun; Younis, Mustafa Z; Younoussi, Zourkaleini; Yu, Chuanhua; Zaki, Maysaa E; Zhao, Yong; Zheng, Yingfeng; Zhou, Maigeng; Zhu, Jun; Zhu, Shankuan; Zou, Xiaonong; Zunt, Joseph R; Lopez, Alan D; Vos, Theo; Murray, Christopher J

    2015-01-01

    BACKGROUND: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for preve

  11. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013 : a systematic analysis for the Global Burden of Disease Study 2013

    NARCIS (Netherlands)

    Forouzanfar, Mohammad H.; Alexander, Lily; Anderson, H. Ross; Bachman, Victoria F.; Biryukov, Stan; Brauer, Michael; Burnett, Richard; Casey, Daniel; Coates, Matthew M.; Cohen, Aaron; Delwiche, Kristen; Estep, Kara; Frostad, Joseph J.; Astha, K. C.; Kyu, Hmwe H.; Moradi-Lakeh, Maziar; Ng, Marie; Slepak, Erica Leigh; Thomas, Bernadette A.; Wagner, Joseph; Aasvang, Gunn Marit; Abbafati, Cristiana; Ozgoren, Ayse Abbasoglu; Abd-Allah, Foad; Abera, Semaw F.; Aboyans, Victor; Abraham, Biju; Abraham, Jerry Puthenpurakal; Abubakar, Ibrahim; Abu-Rmeileh, Niveen M. E.; Aburto, Tania C.; Achoki, Tom; Adelekan, Ademola; Adofo, Koranteng; Adou, Arsene K.; Adsuar, Jose C.; Afshin, Ashkan; Agardh, Emilie E.; Al Khabouri, Mazin J.; Al Lami, Faris H.; Alam, Sayed Saidul; Alasfoor, Deena; Albittar, Mohammed I.; Alegretti, Miguel A.; Aleman, Alicia V.; Alemu, Zewdie A.; Alfonso-Cristancho, Rafael; Alhabib, Samia; Ali, Raghib; Ali, Mohammed K.; Alla, Francois; Allebeck, Peter; Allen, Peter J.; Alsharif, Ubai; Alvarez, Elena; Alvis-Guzman, Nelson; Amankwaa, Adansi A.; Amare, Azmeraw T.; Ameh, Emmanuel A.; Ameli, Omid; Amini, Heresh; Ammar, Walid; Anderson, Benjamin O.; Antonio, Carl Abelardo T.; Anwari, Palwasha; Cunningham, Solveig Argeseanu; Arnlov, Johan; Arsenijevic, Valentina S. Arsic; Artaman, Al; Asghar, Rana J.; Assadi, Reza; Atkins, Lydia S.; Atkinson, Charles; Avila, Marco A.; Awuah, Baffour; Badawi, Alaa; Bahit, Maria C.; Bakfalouni, Talal; Balakrishnan, Kalpana; Balalla, Shivanthi; Balu, Ravi Kumar; Banerjee, Amitava; Barber, Ryan M.; Barker-Collo, Suzanne L.; Barquera, Simon; Barregard, Lars; Barrero, Lope H.; Barrientos-Gutierrez, Tonatiuh; Basto-Abreu, Ana C.; Basu, Arindam; Basu, Sanjay; Basulaiman, Mohammed O.; Ruvalcaba, Carolina Batis; Beardsley, Justin; Bedi, Neeraj; Bekele, Tolesa; Bell, Michelle L.; Benjet, Corina; Bennett, Derrick A.; Benzian, Habib; Bernabe, Eduardo; Beyene, Tariku J.; Bhala, Neeraj; Bhalla, Ashish; Bhutta, Zulfi Qar A.; Bikbov, Boris; Bin Abdulhak, Aref A.; Blore, Jed D.; Blyth, Fiona M.; Bohensky, Megan A.; Basara, Berrak Bora; Borges, Guilherme; Bornstein, Natan M.; Bose, Dipan; Boufous, Soufiane; Bourne, Rupert R.; Brainin, Michael; Brazinova, Alexandra; Breitborde, Nicholas J.; Brenner, Hermann; Briggs, Adam D. M.; Broday, David M.; Brooks, Peter M.; Bruce, Nigel G.; Brugha, Traolach S.; Brunekreef, Bert; Buchbinder, Rachelle; Bui, Linh N.; Bukhman, Gene; Bulloch, Andrew G.; Burch, Michael; Burney, Peter G. J.; Campos-Nonato, Ismael R.; Campuzano, Julio C.; Cantoral, Alejandra J.; Caravanos, Jack; Cardenas, Rosario; Cardis, Elisabeth; Carpenter, David O.; Caso, Valeria; Castaneda-Orjuela, Carlos A.; Castro, Ruben E.; Catala-Lopez, Ferran; Cavalleri, Fiorella; Cavlin, Alanur; Chadha, Vineet K.; Chang, Jung-chen; Charlson, Fiona J.; Chen, Honglei; Chen, Wanqing; Chen, Zhengming; Chiang, Peggy P.; Chimed-Ochir, Odgerel; Chowdhury, Rajiv; Christophi, Costas A.; Chuang, Ting-Wu; Chugh, Sumeet S.; Cirillo, Massimo; Classen, Thomas K. D.; Colistro, Valentina; Colomar, Mercedes; Colquhoun, Samantha M.; Contreras, Alejandra G.; Cooper, Cyrus; Cooperrider, Kimberly; Cooper, Leslie T.; Coresh, Josef; Courville, Karen J.; Criqui, Michael H.; Cuevas-Nasu, Lucia; Damsere-Derry, James; Danawi, Hadi; Dandona, Lalit; Dandona, Rakhi; Dargan, Paul I.; Davis, Adrian; Davitoiu, Dragos V.; Dayama, Anand; de Castro, E. Filipa; De la Cruz-Gongora, Vanessa; De Leo, Diego; de Lima, Graca; Degenhardt, Louisa; del Pozo-Cruz, Borja; Dellavalle, Robert P.; Deribe, Kebede; Derrett, Sarah; Jarlais, Don C. Des; Dessalegn, Muluken; deVeber, Gabrielle A.; Devries, Karen M.; Dharmaratne, Samath D.; Dherani, Mukesh K.; Dicker, Daniel; Ding, Eric L.; Dokova, Klara; Dorsey, E. Ray; Driscoll, Tim R.; Duan, Leilei; Durrani, Adnan M.; Ebel, Beth E.; Ellenbogen, Richard G.; Elshrek, Yousef M.; Endres, Matthias; Ermakov, Sergey P.; Erskine, Holly E.; Eshrati, Babak; Esteghamati, Alireza; Fahimi, Saman; Faraon, Emerito Jose A.; Farzadfar, Farshad; Fay, Derek F. J.; Feigin, Valery L.; Feigl, Andrea B.; Fereshtehnejad, Seyed-Mohammad; Ferrari, Alize J.; Ferri, Cleusa P.; Flaxman, Abraham D.; Fleming, Thomas D.; Foigt, Nataliya; Foreman, Kyle J.; Paleo, Urbano Fra; Franklin, Richard C.; Gabbe, Belinda; Gaffikin, Lynne; Gakidou, Emmanuela; Gamkrelidze, Amiran; Gankpe, Fortune G.; Gansevoort, Ron T.; Garcia-Guerra, Francisco A.; Gasana, Evariste; Geleijnse, Johanna M.; Gessner, Bradford D.; Gething, Pete; Gibney, Katherine B.; Gillum, Richard F.; Ginawi, Ibrahim A. M.; Giroud, Maurice; Giussani, Giorgia; Goenka, Shifalika; Goginashvili, Ketevan; Dantes, Hector Gomez; Gona, Philimon; de Cosio, Teresita Gonzalez; Gonzalez-Castell, Dinorah; Gotay, Carolyn C.; Goto, Atsushi; Gouda, Hebe N.; Guerrant, Richard L.; Gugnani, Harish C.; Guillemin, Francis; Gunnell, David; Gupta, Rahul; Gupta, Rajeev; Gutierrez, Reyna A.; Hafezi-Nejad, Nima; Hagan, Holly; Hagstromer, Maria; Halasa, Yara A.; Hamadeh, Randah R.; Hammami, Mouhanad; Hankey, Graeme J.; Hao, Yuantao; Harb, Hilda L.; Haregu, Tilahun Nigatu; Haro, Josep Maria; Havmoeller, Rasmus; Hay, Simon I.; Hedayati, Mohammad T.; Heredia-Pi, Ileana B.; Hernandez, Lucia; Heuton, Kyle R.; Heydarpour, Pouria; Hijar, Martha; Hoek, Hans W.; Man, Howard J. Hoff; Hornberger, John C.; Hosgood, H. Dean; Hoy, Damian G.; Hsairi, Mohamed; Hu, Guoqing; Hu, Howard; Huang, Cheng; Huang, John J.; Hubbell, Bryan J.; Huiart, Laetitia; Husseini, Abdullatif; Iannarone, Marissa L.; Iburg, Kim M.; Idrisov, Bulat T.; Ikeda, Nayu; Innos, Kaire; Inoue, Manami; Islami, Farhad; Ismayilova, Samaya; Jacobsen, Kathryn H.; Jansen, Henrica A.; Jarvis, Deborah L.; Jassal, Simerjot K.; Jauregui, Alejandra; Jayaraman, Sudha; Jeemon, Panniyammakal; Jensen, Paul N.; Jha, Vivekanand; Jiang, Fan; Jiang, Guohong; Jiang, Ying; Jonas, Jost B.; Juel, Knud; Kan, Haidong; Roseline, Sidibe S. Kany; Karam, Nadim E.; Karch, Andre; Karema, Corine K.; Karthikeyan, Ganesan; Kaul, Anil; Kawakami, Norito; Kazi, Dhruv S.; Kemp, Andrew H.; Kengne, Andre P.; Keren, Andre; Khader, Yousef S.; Khalifa, Shams Eldin Ali Hassan; Khan, Ejaz A.; Khang, Young-Ho; Khatibzadeh, Shahab; Khonelidze, Irma; Kieling, Christian; Kim, Daniel; Kim, Sungroul; Kim, Yunjin; Kimokoti, Ruth W.; Kinfu, Yohannes; Kinge, Jonas M.; Kissela, Brett M.; Kivipelto, Miia; Knibbs, Luke D.; Knudsen, Ann Kristin; Kokubo, Yoshihiro; Kose, M. Rifat; Kosen, Soewarta; Kraemer, Alexander; Kravchenko, Michael; Krishnaswami, Sanjay; Kromhout, Hans; Ku, Tiffany; Defo, Barthelemy Kuate; Bicer, Burcu Kucuk; Kuipers, Ernst J.; Kulkarni, Chanda; Kulkarni, Veena S.; Kumar, G. Anil; Kwan, Gene F.; Lai, Taavi; Balaji, Arjun Lakshmana; Lalloo, Ratilal; Lallukka, Tea; Lam, Hilton; Lan, Qing; Lansingh, Van C.; Larson, Heidi J.; Larsson, Anders; Laryea, Dennis O.; Lavados, Pablo M.; Lawrynowicz, Alicia E.; Leasher, Janet L.; Lee, Jong-Tae; Leigh, James; Leung, Ricky; Levi, Miriam; Li, Yichong; Li, Yongmei; Liang, Juan; Liang, Xiaofeng; Lim, Stephen S.; Lindsay, M. Patrice; Lipshultz, Steven E.; Liu, Shiwei; Liu, Yang; Lloyd, Belinda K.; Logroscino, Giancarlo; London, Stephanie J.; Lopez, Nancy; Lortet-Tieulent, Joannie; Lotufo, Paulo A.; Lozano, Rafael; Lunevicius, Raimundas; Ma, Jixiang; Ma, Stefan; Machado, Vasco M. P.; MacIntyre, Michael F.; Magis-Rodriguez, Carlos; Mahdi, Abbas A.; Majdan, Marek; Malekzadeh, Reza; Mangalam, Srikanth; Mapoma, Christopher C.; Marape, Marape; Marcenes, Wagner; Margolis, David J.; Margono, Christopher; Marks, Guy B.; Martin, Randall V.; Marzan, Melvin B.; Mashal, Mohammad T.; Masiye, Felix; Mason-Jones, Amanda J.; Matsushita, Kunihiro; Matzopoulos, Richard; Mayosi, Bongani M.; Mazorodze, Tasara T.; Mckay, Abigail C.; Mckee, Martin; McLain, Abigail; Meaney, Peter A.; Medina, Catalina; Mehndiratta, Man Mohan; Mejia-Rodriguez, Fabiola; Mekonnen, Wubegzier; Melaku, Yohannes A.; Meltzer, Michele; Memish, Ziad A.; Mendoza, Walter; Mensah, George A.; Meretoja, Atte; Mhimbira, Francis Apolinary; Micha, Renata; Miller, Ted R.; Mills, Edward J.; Misganaw, Awoke; Mishra, Santosh; Ibrahim, Norlinah Mohamed; Mohammad, Karzan A.; Mokdad, Ali H.; Mola, Glen L.; Monasta, Lorenzo; Hernandez, Julio C. Montaez; Montico, Marcella; Moore, Ami R.; Morawska, Lidia; Mori, Rintaro; Moschandreas, Joanna; Moturi, Wilkister N.; Arian, Dariush Mozaff; Mueller, Ulrich O.; Mukaigawara, Mitsuru; Mullany, Erin C.; Murthy, Kinnari S.; Naghavi, Mohsen; Nahas, Ziad; Naheed, Aliya; Naidoo, Kovin S.; Naldi, Luigi; Nand, Devina; Nangia, Vinay; Narayan, K. M. Venkat; Nash, Denis; Neal, Bruce; Nejjari, Chakib; Neupane, Sudan P.; Newton, Charles R.; Ngalesoni, Frida N.; Ngirabega, Jean de Dieu; Nguyen, Grant; Nguyen, Nhung T.; Nieuwenhuijsen, Mark J.; Nisar, Muhammad I.; Nogueira, Jose R.; Nolla, Joan M.; Nolte, Sandra; Norheim, Ole F.; Norman, Rosana E.; Norrving, Bo; Nyakarahuka, Luke; Oh, In-Hwan; Ohkubo, Takayoshi; Olusanya, Bolajoko O.; Omer, Saad B.; Opio, John Nelson; Orozco, Ricardo; Pagcatipunan, Rodolfo S.; Pain, Amanda W.; Pandian, Jeyaraj D.; Panelo, Carlo Irwin A.; Papachristou, Christina; Park, Eun-Kee; Parry, Charles D.; Caicedo, Angel J. Paternina; Patten, Scott B.; Paul, Vinod K.; Pavlin, Boris I.; Pearce, Neil; Pedraza, Lilia S.; Pedroza, Andrea; Stokic, Ljiljana Pejin; Pekericli, Ayfer; Pereira, David M.; Perez-Padilla, Rogelio; Perez-Ruiz, Fernando; Perico, Norberto; Perry, Samuel A. L.; Pervaiz, Aslam; Pesudovs, Konrad; Peterson, Carrie B.; Petzold, Max; Phillips, Michael R.; Phua, Hwee Pin; Plass, Dietrich; Poenaru, Dan; Polanczyk, Guilherme V.; Polinder, Suzanne; Pond, Constance D.; Pope, C. Arden; Pope, Daniel; Popova, Svetlana; Pourmalek, Farshad; Powles, John; Prabhakaran, Dorairaj; Prasad, Noela M.; Qato, Dima M.; Quezada, Amado D.; Quistberg, D. Alex A.; Racape, Lionel; Rafay, Anwar; Rahimi, Kazem; Rahimi-Movaghar, Vafa; Rahman, Sajjad Ur; Raju, Murugesan; Rakovac, Ivo; Rana, Saleem M.; Rao, Mayuree; Razavi, Homie; Reddy, K. Srinath; Refaat, Amany H.; Rehm, Juergen; Remuzzi, Giuseppe; Ribeiro, Antonio L.; Riccio, Patricia M.; Richardson, Lee; Riederer, Anne; Robinson, Margaret; Roca, Anna; Rodriguez, Alina; Rojas-Rueda, David; Romieu, Isabelle; Ronfani, Luca; Room, Robin; Roy, Nobhojit; Ruhago, George M.; Rushton, Lesley; Sabin, Nsanzimana; Sacco, Ralph L.; Saha, Sukanta; Sahathevan, Ramesh; Sahraian, Mohammad Ali; Salomon, Joshua A.; Salvo, Deborah; Sampson, Uchechukwu K.; Sanabria, Juan R.; Sanchez, Luz Maria; Sanchez-Pimienta, Tania G.; Sanchez-Riera, Lidia; Sandar, Logan; Santos, Itamar S.; Sapkota, Amir; Satpathy, Maheswar; Saunders, James E.; Sawhney, Monika; Saylan, Mete I.; Scarborough, Peter; Schmidt, Juergen C.; Schneider, Ione J. C.; Schoettker, Ben; Schwebel, David C.; Scott, James G.; Seedat, Soraya; Sepanlou, Sadaf G.; Serdar, Berrin; Servan-Mori, Edson E.; Shaddick, Gavin; Shahraz, Saeid; Levy, Teresa Shamah; Shangguan, Siyi; She, Jun; Sheikhbahaei, Sara; Shibuya, Kenji; Shin, Hwashin H.; Shinohara, Yukito; Shiri, Rahman; Shishani, Kawkab; Shiue, Ivy; Sigfusdottir, Inga D.; Silberberg, Donald H.; Simard, Edgar P.; Sindi, Shireen; Singh, Abhishek; Singh, Gitanjali M.; Singh, Jasvinder A.; Skirbekk, Vegard; Sliwa, Karen; Soljak, Michael; Soneji, Samir; Soreide, Kjetil; Soshnikov, Sergey; Sposato, Luciano A.; Sreeramareddy, Chandrashekhar T.; Stapelberg, Nicolas J. C.; Stathopoulou, Vasiliki; Steckling, Nadine; Stein, Dan J.; Stein, Murray B.; Stephens, Natalie; Stoeckl, Heidi; Straif, Kurt; Stroumpoulis, Konstantinos; Sturua, Lela; Sunguya, Bruno F.; Swaminathan, Soumya; Swaroop, Mamta; Sykes, Bryan L.; Tabb, Karen M.; Takahashi, Ken; Talongwa, Roberto T.; Tandon, Nikhil; Tanne, David; Tanner, Marcel; Tavakkoli, Mohammad; Ao, Braden J. Te; Teixeira, Carolina M.; Rojo, Martha M. Tellez; Terkawi, Abdullah S.; Texcalac-Sangrador, Jose Luis; Thackway, Sarah V.; Thomson, Blake; Thorne-Lyman, Andrew L.; Thrift, Amanda G.; Thurston, George D.; Tillmann, Taavi; Tobollik, Myriam; Tonelli, Marcello; Topouzis, Fotis; Towbin, Jeff Rey A.; Toyoshima, Hideaki; Traebert, Jeff Erson; Tran, Bach X.; Trasande, Leonardo; Trillini, Matias; Trujillo, Ulises; Dimbuene, Zacharie Tsala; Tsilimbaris, Miltiadis; Tuzcu, Emin Murat; Uchendu, Uche S.; Ukwaja, Kingsley N.; Uzun, Selen B.; van de Vijver, Steven; Van Dingenen, Rita; Van Gool, Coen H.; Van Os, Jim; Varakin, Yuri Y.; Vasankari, Tommi J.; Vasconcelos, Ana Maria N.; Vavilala, Monica S.; Veerman, Lennert J.; Velasquez-Melendez, Gustavo; Venketasubramanian, N.; Vijayakumar, Lakshmi; Villalpando, Salvador; Violante, Francesco S.; Vlassov, Vasiliy Victorovich; Vollset, Stein Emil; Wagner, Gregory R.; Waller, Stephen G.; Wallin, Mitchell T.; Wan, Xia; Wang, Haidong; Wang, JianLi; Wang, Linhong; Wang, Wenzhi; Wang, Yanping; Warouw, Tati S.; Watts, Charlotte H.; Weichenthal, Scott; Weiderpass, Elisabete; Weintraub, Robert G.; Werdecker, Andrea; Wessells, K. Ryan; Westerman, Ronny; Whiteford, Harvey A.; Wilkinson, James D.; Williams, Hywel C.; Williams, Thomas N.; Woldeyohannes, Solomon M.; Wolfe, Charles D. A.; Wong, John Q.; Woolf, Anthony D.; Wright, Jonathan L.; Wurtz, Brittany; Xu, Gelin; Yan, Lijing L.; Yang, Gonghuan; Yano, Yuichiro; Ye, Pengpeng; Yenesew, Muluken; Yentuer, Goekalp K.; Yip, Paul; Yonemoto, Naohiro; Yoon, Seok-Jun; Younis, Mustafa Z.; Younoussi, Zourkaleini; Yu, Chuanhua; Zaki, Maysaa E.; Zhao, Yong; Zheng, Yingfeng; Zhou, Maigeng; Zhu, Jun; Zhu, Shankuan; Zou, Xiaonong; Zunt, Joseph R.; Lopez, Alan D.; Vos, Theo; Murray, Christopher J.

    2015-01-01

    Background The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for preven

  12. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013 : a systematic analysis for the Global Burden of Disease Study 2013

    NARCIS (Netherlands)

    Forouzanfar, Mohammad H; Alexander, Lily; Anderson, H Ross; Bachman, Victoria F; Biryukov, Stan; Brauer, Michael; Burnett, Richard; Casey, Daniel; Coates, Matthew M; Cohen, Aaron; Delwiche, Kristen; Estep, Kara; Frostad, Joseph J; Kc, Astha; Kyu, Hmwe H; Moradi-Lakeh, Maziar; Ng, Marie; Slepak, Erica Leigh; Thomas, Bernadette A; Wagner, Joseph; Aasvang, Gunn Marit; Abbafati, Cristiana; Ozgoren, Ayse Abbasoglu; Abd-Allah, Foad; Abera, Semaw F; Aboyans, Victor; Abraham, Biju; Abraham, Jerry Puthenpurakal; Abubakar, Ibrahim; Abu-Rmeileh, Niveen M E; Aburto, Tania C; Achoki, Tom; Adelekan, Ademola; Adofo, Koranteng; Adou, Arsène K; Adsuar, José C; Afshin, Ashkan; Agardh, Emilie E; Al Khabouri, Mazin J; Al Lami, Faris H; Alam, Sayed Saidul; Alasfoor, Deena; Albittar, Mohammed I; Alegretti, Miguel A; Aleman, Alicia V; Alemu, Zewdie A; Alfonso-Cristancho, Rafael; Alhabib, Samia; Ali, Raghib; Ali, Mohammed K; Alla, François; Allebeck, Peter; Allen, Peter J; Alsharif, Ubai; Alvarez, Elena; Alvis-Guzman, Nelson; Amankwaa, Adansi A; Amare, Azmeraw T; Ameh, Emmanuel A; Ameli, Omid; Amini, Heresh; Ammar, Walid; Anderson, Benjamin O; Antonio, Carl Abelardo T; Anwari, Palwasha; Cunningham, Solveig Argeseanu; Arnlöv, Johan; Arsenijevic, Valentina S Arsic; Artaman, Al; Asghar, Rana J; Assadi, Reza; Atkins, Lydia S; Atkinson, Charles; Avila, Marco A; Awuah, Baffour; Badawi, Alaa; Bahit, Maria C; Bakfalouni, Talal; Balakrishnan, Kalpana; Balalla, Shivanthi; Balu, Ravi Kumar; Banerjee, Amitava; Barber, Ryan M; Barker-Collo, Suzanne L; Barquera, Simon; Barregard, Lars; Barrero, Lope H; Barrientos-Gutierrez, Tonatiuh; Basto-Abreu, Ana C; Basu, Arindam; Basu, Sanjay; Basulaiman, Mohammed O; Ruvalcaba, Carolina Batis; Beardsley, Justin; Bedi, Neeraj; Bekele, Tolesa; Bell, Michelle L; Benjet, Corina; Bennett, Derrick A; Benzian, Habib; Bernabé, Eduardo; Beyene, Tariku J; Bhala, Neeraj; Bhalla, Ashish; Bhutta, Zulfiqar A; Bikbov, Boris; Abdulhak, Aref A Bin; Blore, Jed D; Blyth, Fiona M; Bohensky, Megan A; Başara, Berrak Bora; Borges, Guilherme; Bornstein, Natan M; Bose, Dipan; Boufous, Soufiane; Bourne, Rupert R; Brainin, Michael; Brazinova, Alexandra; Breitborde, Nicholas J; Brenner, Hermann; Briggs, Adam D M; Broday, David M; Brooks, Peter M; Bruce, Nigel G; Brugha, Traolach S; Brunekreef, Bert; Buchbinder, Rachelle; Bui, Linh N; Bukhman, Gene; Bulloch, Andrew G; Burch, Michael; Burney, Peter G J; Campos-Nonato, Ismael R; Campuzano, Julio C; Cantoral, Alejandra J; Caravanos, Jack; Cárdenas, Rosario; Cardis, Elisabeth; Carpenter, David O; Caso, Valeria; Castañeda-Orjuela, Carlos A; Castro, Ruben E; Catalá-López, Ferrán; Cavalleri, Fiorella; Çavlin, Alanur; Chadha, Vineet K; Chang, Jung-Chen; Charlson, Fiona J; Chen, Honglei; Chen, Wanqing; Chen, Zhengming; Chiang, Peggy P; Chimed-Ochir, Odgerel; Chowdhury, Rajiv; Christophi, Costas A; Chuang, Ting-Wu; Chugh, Sumeet S; Cirillo, Massimo; Claßen, Thomas Kd; Colistro, Valentina; Colomar, Mercedes; Colquhoun, Samantha M; Contreras, Alejandra G; Cooper, Cyrus; Cooperrider, Kimberly; Cooper, Leslie T; Coresh, Josef; Courville, Karen J; Criqui, Michael H; Cuevas-Nasu, Lucia; Damsere-Derry, James; Danawi, Hadi; Dandona, Lalit; Dandona, Rakhi; Dargan, Paul I; Davis, Adrian; Davitoiu, Dragos V; Dayama, Anand; de Castro, E Filipa; De la Cruz-Góngora, Vanessa; De Leo, Diego; de Lima, Graça; Degenhardt, Louisa; Del Pozo-Cruz, Borja; Dellavalle, Robert P; Deribe, Kebede; Derrett, Sarah; Jarlais, Don C Des; Dessalegn, Muluken; deVeber, Gabrielle A; Devries, Karen M; Dharmaratne, Samath D; Dherani, Mukesh K; Dicker, Daniel; Ding, Eric L; Dokova, Klara; Dorsey, E Ray; Driscoll, Tim R; Duan, Leilei; Durrani, Adnan M; Ebel, Beth E; Ellenbogen, Richard G; Elshrek, Yousef M; Endres, Matthias; Ermakov, Sergey P; Erskine, Holly E; Eshrati, Babak; Esteghamati, Alireza; Fahimi, Saman; Faraon, Emerito Jose A; Farzadfar, Farshad; Fay, Derek F J; Feigin, Valery L; Feigl, Andrea B; Fereshtehnejad, Seyed-Mohammad; Ferrari, Alize J; Ferri, Cleusa P; Flaxman, Abraham D; Fleming, Thomas D; Foigt, Nataliya; Foreman, Kyle J; Paleo, Urbano Fra; Franklin, Richard C; Gabbe, Belinda; Gaffikin, Lynne; Gakidou, Emmanuela; Gamkrelidze, Amiran; Gankpé, Fortuné G; Gansevoort, Ron T; García-Guerra, Francisco A; Gasana, Evariste; Geleijnse, Johanna M; Gessner, Bradford D; Gething, Pete; Gibney, Katherine B; Gillum, Richard F; Ginawi, Ibrahim A M; Giroud, Maurice; Giussani, Giorgia; Goenka, Shifalika; Goginashvili, Ketevan; Dantes, Hector Gomez; Gona, Philimon; de Cosio, Teresita Gonzalez; González-Castell, Dinorah; Gotay, Carolyn C; Goto, Atsushi; Gouda, Hebe N; Guerrant, Richard L; Gugnani, Harish C; Guillemin, Francis; Gunnell, David; Gupta, Rahul; Gupta, Rajeev; Gutiérrez, Reyna A; Hafezi-Nejad, Nima; Hagan, Holly; Hagstromer, Maria; Halasa, Yara A; Hamadeh, Randah R; Hammami, Mouhanad; Hankey, Graeme J; Hao, Yuantao; Harb, Hilda L; Haregu, Tilahun Nigatu; Haro, Josep Maria; Havmoeller, Rasmus; Hay, Simon I; Hedayati, Mohammad T; Heredia-Pi, Ileana B; Hernandez, Lucia; Heuton, Kyle R; Heydarpour, Pouria; Hijar, Martha; Hoek, Hans W; Hoffman, Howard J; Hornberger, John C; Hosgood, H Dean; Hoy, Damian G; Hsairi, Mohamed; Hu, Guoqing; Hu, Howard; Huang, Cheng; Huang, John J; Hubbell, Bryan J; Huiart, Laetitia; Husseini, Abdullatif; Iannarone, Marissa L; Iburg, Kim M; Idrisov, Bulat T; Ikeda, Nayu; Innos, Kaire; Inoue, Manami; Islami, Farhad; Ismayilova, Samaya; Jacobsen, Kathryn H; Jansen, Henrica A; Jarvis, Deborah L; Jassal, Simerjot K; Jauregui, Alejandra; Jayaraman, Sudha; Jeemon, Panniyammakal; Jensen, Paul N; Jha, Vivekanand; Jiang, Fan; Jiang, Guohong; Jiang, Ying; Jonas, Jost B; Juel, Knud; Kan, Haidong; Roseline, Sidibe S Kany; Karam, Nadim E; Karch, André; Karema, Corine K; Karthikeyan, Ganesan; Kaul, Anil; Kawakami, Norito; Kazi, Dhruv S; Kemp, Andrew H; Kengne, Andre P; Keren, Andre; Khader, Yousef S; Khalifa, Shams Eldin Ali Hassan; Khan, Ejaz A; Khang, Young-Ho; Khatibzadeh, Shahab; Khonelidze, Irma; Kieling, Christian; Kim, Daniel; Kim, Sungroul; Kim, Yunjin; Kimokoti, Ruth W; Kinfu, Yohannes; Kinge, Jonas M; Kissela, Brett M; Kivipelto, Miia; Knibbs, Luke D; Knudsen, Ann Kristin; Kokubo, Yoshihiro; Kose, M Rifat; Kosen, Soewarta; Kraemer, Alexander; Kravchenko, Michael; Krishnaswami, Sanjay; Kromhout, Hans; Ku, Tiffany; Defo, Barthelemy Kuate; Bicer, Burcu Kucuk; Kuipers, Ernst J; Kulkarni, Chanda; Kulkarni, Veena S; Kumar, G Anil; Kwan, Gene F; Lai, Taavi; Balaji, Arjun Lakshmana; Lalloo, Ratilal; Lallukka, Tea; Lam, Hilton; Lan, Qing; Lansingh, Van C; Larson, Heidi J; Larsson, Anders; Laryea, Dennis O; Lavados, Pablo M; Lawrynowicz, Alicia E; Leasher, Janet L; Lee, Jong-Tae; Leigh, James; Leung, Ricky; Levi, Miriam; Li, Yichong; Li, Yongmei; Liang, Juan; Liang, Xiaofeng; Lim, Stephen S; Lindsay, M Patrice; Lipshultz, Steven E; Liu, Shiwei; Liu, Yang; Lloyd, Belinda K; Logroscino, Giancarlo; London, Stephanie J; Lopez, Nancy; Lortet-Tieulent, Joannie; Lotufo, Paulo A; Lozano, Rafael; Lunevicius, Raimundas; Ma, Jixiang; Ma, Stefan; Machado, Vasco M P; MacIntyre, Michael F; Magis-Rodriguez, Carlos; Mahdi, Abbas A; Majdan, Marek; Malekzadeh, Reza; Mangalam, Srikanth; Mapoma, Christopher C; Marape, Marape; Marcenes, Wagner; Margolis, David J; Margono, Christopher; Marks, Guy B; Martin, Randall V; Marzan, Melvin B; Mashal, Mohammad T; Masiye, Felix; Mason-Jones, Amanda J; Matsushita, Kunihiro; Matzopoulos, Richard; Mayosi, Bongani M; Mazorodze, Tasara T; McKay, Abigail C; McKee, Martin; McLain, Abigail; Meaney, Peter A; Medina, Catalina; Mehndiratta, Man Mohan; Mejia-Rodriguez, Fabiola; Mekonnen, Wubegzier; Melaku, Yohannes A; Meltzer, Michele; Memish, Ziad A; Mendoza, Walter; Mensah, George A; Meretoja, Atte; Mhimbira, Francis Apolinary; Micha, Renata; Miller, Ted R; Mills, Edward J; Misganaw, Awoke; Mishra, Santosh; Ibrahim, Norlinah Mohamed; Mohammad, Karzan A; Mokdad, Ali H; Mola, Glen L; Monasta, Lorenzo; Hernandez, Julio C Montañez; Montico, Marcella; Moore, Ami R; Morawska, Lidia; Mori, Rintaro; Moschandreas, Joanna; Moturi, Wilkister N; Mozaffarian, Dariush; Mueller, Ulrich O; Mukaigawara, Mitsuru; Mullany, Erin C; Murthy, Kinnari S; Naghavi, Mohsen; Nahas, Ziad; Naheed, Aliya; Naidoo, Kovin S; Naldi, Luigi; Nand, Devina; Nangia, Vinay; Narayan, Km Venkat; Nash, Denis; Neal, Bruce; Nejjari, Chakib; Neupane, Sudan P; Newton, Charles R; Ngalesoni, Frida N; de Dieu Ngirabega, Jean; Nguyen, Grant; Nguyen, Nhung T; Nieuwenhuijsen, Mark J; Nisar, Muhammad I; Nogueira, José R; Nolla, Joan M; Nolte, Sandra; Norheim, Ole F; Norman, Rosana E; Norrving, Bo; Nyakarahuka, Luke; Oh, In-Hwan; Ohkubo, Takayoshi; Olusanya, Bolajoko O; Omer, Saad B; Opio, John Nelson; Orozco, Ricardo; Pagcatipunan, Rodolfo S; Pain, Amanda W; Pandian, Jeyaraj D; Panelo, Carlo Irwin A; Papachristou, Christina; Park, Eun-Kee; Parry, Charles D; Caicedo, Angel J Paternina; Patten, Scott B; Paul, Vinod K; Pavlin, Boris I; Pearce, Neil; Pedraza, Lilia S; Pedroza, Andrea; Stokic, Ljiljana Pejin; Pekericli, Ayfer; Pereira, David M; Perez-Padilla, Rogelio; Perez-Ruiz, Fernando; Perico, Norberto; Perry, Samuel A L; Pervaiz, Aslam; Pesudovs, Konrad; Peterson, Carrie B; Petzold, Max; Phillips, Michael R; Phua, Hwee Pin; Plass, Dietrich; Poenaru, Dan; Polanczyk, Guilherme V; Polinder, Suzanne; Pond, Constance D; Pope, C Arden; Pope, Daniel; Popova, Svetlana; Pourmalek, Farshad; Powles, John; Prabhakaran, Dorairaj; Prasad, Noela M; Qato, Dima M; Quezada, Amado D; Quistberg, D Alex A; Racapé, Lionel; Rafay, Anwar; Rahimi, Kazem; Rahimi-Movaghar, Vafa; Rahman, Sajjad Ur; Raju, Murugesan; Rakovac, Ivo; Rana, Saleem M; Rao, Mayuree; Razavi, Homie; Reddy, K Srinath; Refaat, Amany H; Rehm, Jürgen; Remuzzi, Giuseppe; Ribeiro, Antonio L; Riccio, Patricia M; Richardson, Lee; Riederer, Anne; Robinson, Margaret; Roca, Anna; Rodriguez, Alina; Rojas-Rueda, David; Romieu, Isabelle; Ronfani, Luca; Room, Robin; Roy, Nobhojit; Ruhago, George M; Rushton, Lesley; Sabin, Nsanzimana; Sacco, Ralph L; Saha, Sukanta; Sahathevan, Ramesh; Sahraian, Mohammad Ali; Salomon, Joshua A; Salvo, Deborah; Sampson, Uchechukwu K; Sanabria, Juan R; Sanchez, Luz Maria; Sánchez-Pimienta, Tania G; Sanchez-Riera, Lidia; Sandar, Logan; Santos, Itamar S; Sapkota, Amir; Satpathy, Maheswar; Saunders, James E; Sawhney, Monika; Saylan, Mete I; Scarborough, Peter; Schmidt, Jürgen C; Schneider, Ione J C; Schöttker, Ben; Schwebel, David C; Scott, James G; Seedat, Soraya; Sepanlou, Sadaf G; Serdar, Berrin; Servan-Mori, Edson E; Shaddick, Gavin; Shahraz, Saeid; Levy, Teresa Shamah; Shangguan, Siyi; She, Jun; Sheikhbahaei, Sara; Shibuya, Kenji; Shin, Hwashin H; Shinohara, Yukito; Shiri, Rahman; Shishani, Kawkab; Shiue, Ivy; Sigfusdottir, Inga D; Silberberg, Donald H; Simard, Edgar P; Sindi, Shireen; Singh, Abhishek; Singh, Gitanjali M; Singh, Jasvinder A; Skirbekk, Vegard; Sliwa, Karen; Soljak, Michael; Soneji, Samir; Søreide, Kjetil; Soshnikov, Sergey; Sposato, Luciano A; Sreeramareddy, Chandrashekhar T; Stapelberg, Nicolas J C; Stathopoulou, Vasiliki; Steckling, Nadine; Stein, Dan J; Stein, Murray B; Stephens, Natalie; Stöckl, Heidi; Straif, Kurt; Stroumpoulis, Konstantinos; Sturua, Lela; Sunguya, Bruno F; Swaminathan, Soumya; Swaroop, Mamta; Sykes, Bryan L; Tabb, Karen M; Takahashi, Ken; Talongwa, Roberto T; Tandon, Nikhil; Tanne, David; Tanner, Marcel; Tavakkoli, Mohammad; Te Ao, Braden J; Teixeira, Carolina M; Téllez Rojo, Martha M; Terkawi, Abdullah S; Texcalac-Sangrador, José Luis; Thackway, Sarah V; Thomson, Blake; Thorne-Lyman, Andrew L; Thrift, Amanda G; Thurston, George D; Tillmann, Taavi; Tobollik, Myriam; Tonelli, Marcello; Topouzis, Fotis; Towbin, Jeffrey A; Toyoshima, Hideaki; Traebert, Jefferson; Tran, Bach X; Trasande, Leonardo; Trillini, Matias; Trujillo, Ulises; Dimbuene, Zacharie Tsala; Tsilimbaris, Miltiadis; Tuzcu, Emin Murat; Uchendu, Uche S; Ukwaja, Kingsley N; Uzun, Selen B; van de Vijver, Steven; Van Dingenen, Rita; van Gool, Coen H; van Os, Jim; Varakin, Yuri Y; Vasankari, Tommi J; Vasconcelos, Ana Maria N; Vavilala, Monica S; Veerman, Lennert J; Velasquez-Melendez, Gustavo; Venketasubramanian, N; Vijayakumar, Lakshmi; Villalpando, Salvador; Violante, Francesco S; Vlassov, Vasiliy Victorovich; Vollset, Stein Emil; Wagner, Gregory R; Waller, Stephen G; Wallin, Mitchell T; Wan, Xia; Wang, Haidong; Wang, JianLi; Wang, Linhong; Wang, Wenzhi; Wang, Yanping; Warouw, Tati S; Watts, Charlotte H; Weichenthal, Scott; Weiderpass, Elisabete; Weintraub, Robert G; Werdecker, Andrea; Wessells, K Ryan; Westerman, Ronny; Whiteford, Harvey A; Wilkinson, James D; Williams, Hywel C; Williams, Thomas N; Woldeyohannes, Solomon M; Wolfe, Charles D A; Wong, John Q; Woolf, Anthony D; Wright, Jonathan L; Wurtz, Brittany; Xu, Gelin; Yan, Lijing L; Yang, Gonghuan; Yano, Yuichiro; Ye, Pengpeng; Yenesew, Muluken; Yentür, Gökalp K; Yip, Paul; Yonemoto, Naohiro; Yoon, Seok-Jun; Younis, Mustafa Z; Younoussi, Zourkaleini; Yu, Chuanhua; Zaki, Maysaa E; Zhao, Yong; Zheng, Yingfeng; Zhou, Maigeng; Zhu, Jun; Zhu, Shankuan; Zou, Xiaonong; Zunt, Joseph R; Lopez, Alan D; Vos, Theo; Murray, Christopher J

    2015-01-01

    BACKGROUND: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for preve

  13. Work and Risk: Perceptions of Nuclear-Power Personnel. a Study in Grounded Theory.

    Science.gov (United States)

    Fields, Claire Dewitt

    1992-01-01

    The utility industry has devoted time and money to assure personnel within nuclear power plants are informed about occupational risks. Radiation-protection training programs are designed to present information to employees about occupational radiation and protective procedures. Work -related concerns are known to create stress, affect the morale of the workforce, influence collective bargaining, and increase compensation claims. This study was designed to determine perceptions of risk among employees of nuclear power plants and identify variables that influence these perceptions. Four power plants were included in the study, one in Canada and three in the United States. Data were generated through participant observations and interviews of 350 participants during a period of 3 weeks at each plant. Data were gathered and analyzed following procedures advanced by Grounded Theory, a naturalistic methodology used in this study. Training content, information, and communication materials were additional sources of data. Findings indicated employees believed health and safety risks existed within the work environment. Perceptions of risk were influenced by training quality, the work environment, nuclear myths and images of the general public, and fears of family members. Among the three groups of workers, administration personnel, security personnel, and radiation workers, the latter identified a larger number of risks. Workers perceived radiation risks, shift work, and steam pipe ruptures as high-level concerns. Experiencing stress, making mistakes, and fear of sabotage were concerns shared among all employee groups at various levels of concern. Strategies developed by employees were used to control risk. Strategies included teamwork, humor, monitoring, avoidance, reframing, and activism. When risks were perceived as uncontrollable, the employee left the plant. A coping strategy of transferring concerns about radiological risks to nonradiological risks were uncovered in

  14. Drinking, Drug Abuse Doubles Veterans' Suicide Risk: Study

    Science.gov (United States)

    ... are also dealing with depression, schizophrenia, bipolar disorder, post-traumatic stress disorder or anxiety, according to the researchers. Two-thirds of the suicides in the study involved firearms, so gun safety ...

  15. Estrogen Metabolism and Prostate Cancer Risk: A Prospective Study

    Science.gov (United States)

    2007-05-01

    hormone therapy, nonprescription hormones (e.g., melatonin and dehydroepiandrosterone), black cohosh, tamoxifen, raloxifene, diabetes medication...The follow-up was conducted in collaboration with another NIH-funded study, the “Epidemiology of Type-2 Diabetes ” study, which is a prospective cohort...The re-call included participants without history of cancer, cardiovascular diseases, and clinically defined type-2 diabetes at baseline interviewed

  16. Typology of Perceived Risk in Foreign Traveling (Case Study: Inbound Tourists who Visited Isfahan)

    OpenAIRE

    Amin Tslimi; Bahram Ranjbarian; Mohammad Ghafari

    2013-01-01

    The successful of a tourism destination is depended on reinforcement of tourist’s encouraging factors and elimination of discouraging factors. Tourist’s perception of risk is a disincentive factor that influences tourist’s intention for traveling to that tourism destination. That is why this study has focused to identify and typology the perceived risks by inbound tourists who visited Isfahan. The statistical population of the study is inbound tourists who visited Isfahan during April and Mar...

  17. An approach for integrating toxicogenomic data in risk assessment: The dibutyl phthalate case study

    Energy Technology Data Exchange (ETDEWEB)

    Euling, Susan Y., E-mail: euling.susan@epa.gov [National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC (United States); Thompson, Chad M. [ToxStrategies, Inc., 23501 Cinco Ranch Blvd., Suite G265, Katy, TX 77494 (United States); Chiu, Weihsueh A. [National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC (United States); Benson, Robert [U.S. Environmental Protection Agency, Region 8, Mail code 8P-W, 1595 Wynkoop Street, Denver, CO 80202 (United States)

    2013-09-15

    An approach for evaluating and integrating genomic data in chemical risk assessment was developed based on the lessons learned from performing a case study for the chemical dibutyl phthalate. A case study prototype approach was first developed in accordance with EPA guidance and recommendations of the scientific community. Dibutyl phthalate (DBP) was selected for the case study exercise. The scoping phase of the dibutyl phthalate case study was conducted by considering the available DBP genomic data, taken together with the entire data set, for whether they could inform various risk assessment aspects, such as toxicodynamics, toxicokinetics, and dose–response. A description of weighing the available dibutyl phthalate data set for utility in risk assessment provides an example for considering genomic data for future chemical assessments. As a result of conducting the scoping process, two questions—Do the DBP toxicogenomic data inform 1) the mechanisms or modes of action?, and 2) the interspecies differences in toxicodynamics?—were selected to focus the case study exercise. Principles of the general approach include considering the genomics data in conjunction with all other data to determine their ability to inform the various qualitative and/or quantitative aspects of risk assessment, and evaluating the relationship between the available genomic and toxicity outcome data with respect to study comparability and phenotypic anchoring. Based on experience from the DBP case study, recommendations and a general approach for integrating genomic data in chemical assessment were developed to advance the broader effort to utilize 21st century data in risk assessment. - Highlights: • Performed DBP case study for integrating genomic data in risk assessment • Present approach for considering genomic data in chemical risk assessment • Present recommendations for use of genomic data in chemical risk assessment.

  18. Increased risk of hip fractures in patients with dementia: a nationwide population-based study

    OpenAIRE

    Wang, Hao-Kuang; Hung, Chao-Ming; Lin, Sheng-Hsiang; Tai, Yi-Cheng; Lu, Kang; Liliang, Po-Chou; Lin, Chi-Wei; Lee, Yi-Che; Fang, Pei-Hsuan; Chang, Li-Ching; Li, Ying-Chun

    2014-01-01

    Background Dementia has been associated with an increased risk of hip fracture. However, little research has been conducted on the impact of dementia on wrist or vertebral fracture development. The aim of this study was to investigate whether dementia is a risk factor for different types of fracture in Taiwan. Methods The study sample was drawn from Taiwan’s National Health Insurance Research Database of reimbursement claims, and comprised 1408 patients who visited ambulatory care centers or ...

  19. 'Prediction models for risk of developing type 2 diabetes: systematic literature search and independent external validation study'

    NARCIS (Netherlands)

    Beulens, Joline W J; Abbasi, Ali; Peelen, Linda M; Spijkerman, Annemieke M W; van der A, Daphne L; Corpeleijn, Eva; Bakker, Stephan J L; van der Schouw, Yvonne T

    2013-01-01

    OBJECTIVE: To validate risk scores to predict occurrence of type 2 diabetes in the Dutch population. DESIGN: Prospective cohort study. METHODS: Twelve basic risk scores and 13 extensive risk scores with biomarkers were used to predict the risk of developing type 2 diabetes during 7.5 years in a pros

  20. A Study of the Perception of Health Risks among College Students in China

    Directory of Open Access Journals (Sweden)

    Chenggang Zhang

    2013-05-01

    Full Text Available The present survey was designed to investigate the perception of health risks among college students in China. The data are the responses of a sample of 3,069 college students at one university to surveys that include measures of several dimensions of public judgments about fifteen specific hazards. Chinese college students conveyed their concerns as falling into three broad categories: Environmental (e.g., global warming, natural catastrophes, the ozone hole, air pollution, chemical pollution, pesticides in food, Technological (e.g., nuclear power stations, thermal power, genetically modified food, medical X-rays, and Social (cigarette smoking, drinking alcohol, overtime study or work, mental stress, motor vehicle accidents. The data were collected with a self-report questionnaire. Descriptive statistics were used to illustrate the levels of perceived risk according to the percent of “high risk” responses as well as the mean response values. Generally, the hazards that were perceived as posing the greatest health risk were those belonging to the social health risks; items related to technology risks received the lowest percentage of “high health risk” rankings. Traditional environmental risks such as natural catastrophes, pollution issues (chemical pollution, air pollution, and pesticides in food were ranked as being relatively high risks. The respondents were less concerned about new emerging issues and long-term environmental risks (global warming. In this survey, motor vehicle accidents were considered to be a “high health risk” by the greatest percentage of respondents. Generally speaking, the female respondents’ degree of recognition of health risks is higher than that of male respondents. Only for the item of smoking was the male respondents’ degree higher than that of females. There is also a geographic imbalance in the health risk perceptions. The degree of recognition of health risks from respondents in municipalities

  1. Risk Assessment for Natural Gas Hydrate Carriers: A Hazard Identification (HAZID Study

    Directory of Open Access Journals (Sweden)

    Kipyoung Kim

    2015-04-01

    Full Text Available Sea transport of natural gas in the form of hydrate pellets is a new technological approach. Introducing new technologies bears raises the possibility of introducing unknown risks or—in case of alternatives for already existing technical solutions—higher risk, either human-, environmental-, or property-related. The option of gas transport by natural gas hydrate pellets has been introduced within the Korean joint research project. One key task was the safety evaluation of the novel natural gas hydrate carrier (NGH carrier developed in the project. The aim of this work was to support and assess the risk aspects of the development to ensure that the risk level for the newly developed concept is as low as for existing competing concepts, especially LNG carriers. The NGH carrier is based on the concept of the self-preservation effect and thereby preserves NGH in the form of pellets at atmospheric pressure and temperatures lower than −20 °C. In order to identify all the possible hazards in the system and then enhance the system safety, a Hazard Identification (HAZID study was conducted. As a result of the HAZID, 80 identified hazards in total were explored and ranked in terms of risk index for the semi-quantitative risk evaluation. Among the hazards identified, three hazards were found to have unacceptable risk level and twenty eight to have acceptable but ALARP risk level. Regarding the hazards with unacceptable risk or ALARP risk, additional safety actions and recommendations for risk control were discussed and proposed in a SAFETY ACTION REGISTER, which would be considered and utilized by designers when developing the detailed system design in the future. In conclusion, the overall safety level of the NGH carrier is considered acceptable. However, it was found that a few external hazards associated with extremely harsh weather could be critical threats to the system. Relevant safety actions against them, therefore, must be provided in the

  2. Perception of risk for Domoic Acid related health problems: A Cross-cultural study.

    Science.gov (United States)

    Roberts, Sparkle M; Grattan, Lynn M; Toben, Alexandra C; Ausherman, Christina; Trainer, Vera; Tracy, Kate; Morris, J Glenn

    2016-07-01

    Risk perception is a complex process that refers to the way people approach, think about and interpret risks in their environment. An important element of risk perception is that it is culturally situated. Since HAB's can present a health risk in many places around the world, looking at cultural parameters for understanding and interpreting risks are important. This study examined how two different groups of people perceive the potential health risks of low level exposure to domoic acid (DA) through razor clam consumption. The risk perceptions of Washington State, USA coastal dwelling Native American nations (NA) were compared to that of a community sample of recreational razor clam harvesters (CRH). Overall, the findings support the hypothesis that cultural and community specific contexts impact the perception of risk of a DA related illness. Specifically, the NA sample was distinguished by worrying more about ocean pollution, attributing DA risks to climate change, expressing concerns about the potential impact of DA on future generations, and feeling better informed than the CRH group. The CRH group were more likely to attribute the DA problem to anthropogenic or industrial causes; and view the risk of health problems as lower than that associated with smoking, high cholesterol, anxiety or depression, alcoholism, high blood pressure or obesity. The CRH group was also more likely to turn to the media for DA related information. Both groups trust the decisions of state and tribe health and natural resources officials and demonstrated a complex pattern of findings that involved gender. It was recommended that risk communication and outreach activities are designed to take into consideration factors that specifically apply to each cultural community.

  3. Allocating Risks in Public-Private Partnerships Using a Transaction Cost Economic Approach: A Case Study

    Directory of Open Access Journals (Sweden)

    Xioa-Hua Jin

    2012-11-01

    Full Text Available Public-private partnership (PPP projects are often characterisedby increased complexity and uncertainty due to their idiosyncrasyin the management and delivery processes such as long-termlifecycle, incomplete contracting, and the multitude of stakeholders.An appropriate risk allocation is particularly crucial to achievingproject success. This paper focuses on the risk allocation in PPPprojects and argues that the transaction cost economics (TCEtheory can integrate the economics part, which is currently missing,into the risk management research. A TCE-based approach isproposed as a logical framework for allocating risks between publicand private sectors in PPP projects. A case study of the SouthernCross Station redevelopment project in Australia is presented toillustrate the approach. The allocation of important risks is putunder scrutiny. Lessons learnt are discussed and alternativemanagement approaches drawing on TCE theory are proposed.

  4. DVT prophylaxis after TKA: routine anticoagulation vs risk screening approach - a randomized study.

    Science.gov (United States)

    Kulshrestha, Vikas; Kumar, Santhosh

    2013-12-01

    The American College of Chest Physicians (ACCP) recommended routine anticoagulation for thromboprophylaxis in patients undergoing lower limb arthroplasty. We compared results of routine anticoagulation Vs risk stratified approach for Deep Venous Thrombosis (DVT) prophylaxis after TKA in terms of symptomatic DVT and wound complications. Nine hundred TKAs done in 673 patients were randomized after DVT risk screening to routine anticoagulation (n = 450) or to risk stratification (n = 450) and selective anticoagulation. 194 patients in the risk screening group received only Aspirin. Primary outcome was symptomatic DVT and wound complication. This randomized study showed that the symptomatic DVT rates after TKA were similar whether patients were routinely anticoagulated or selectively anticoagulated after risk screening. However there was a significantly higher incidence of wound complications (P < 0.014) after routine anticoagulation.

  5. Study of Enterprises Marketing Risk Early Warning System Based on BP Neural Network Model

    Institute of Scientific and Technical Information of China (English)

    ZHOU Mei-hua; WANG Fu-dong; ZHANG Hong-hong

    2006-01-01

    For effectively early warning the marketing risk caused along with the varied environment, a BP neural network method was introduced on the basis of analyzing the shortcomings of the risk early warning method, and combined with the practical conditions of dairy enterprises, the index system caused by the marketing risk was also studied. The principal component method was used for screening the indexes, the grades and critical values of the marketing risk were determined. Through the configuration of BP network, node processing and error analysis, the early warning results of the marketing risk were obtained. The results indicate that BP neural network method can be effectively applied through the function approach in the marketing early warning with incomplete information and complex varied conditions.

  6. Risk assessment of oil and gas well drilling activities in Iran - a case study: human factors.

    Science.gov (United States)

    Amir-Heidari, Payam; Farahani, Hadi; Ebrahemzadih, Mehrzad

    2015-01-01

    Oil and gas well drilling activities are associated with numerous hazards which have the potential to cause injury or harm for people, property and the environment. These hazards are also a threat for the reputation of drilling companies. To prevent accidents and undesired events in drilling operations it is essential to identify, evaluate, assess and control the attendant risks. In this work, a structured methodology is proposed for risk assessment of drilling activities. A case study is performed to identify, analyze and assess the risks arising from human factors in one of the on shore drilling sites in southern Iran. A total of 17 major hazards were identified and analyzed using the proposed methodology. The results showed that the residual risks of 100% of these hazards were in the acceptable or transitional zone, and their levels were expected to be lowered further by proper controls. This structured methodology may also be used in other drilling sites and companies for assessing the risks.

  7. Alcohol consumption and later risk of hospitalization with psychiatric disorders: prospective cohort study

    DEFF Research Database (Denmark)

    Flensborg-Madsen, Trine; Becker, Ulrik; Grønbæk, Morten

    2011-01-01

    measured through registers. For women, the overall pattern showed that drinking above the sensible limits increased the risk of psychiatric disorders in general, especially for anxiety disorders where women drinking above the sensible drinking limits had a risk of 2.00 (confidence interval: 1.......31-3.04) compared to women drinking below the sensible drinking limits. For men, the risk functions were slightly U-shaped; thus, a weekly low or moderate alcohol intake seemed to have a protective effect towards developing psychiatric disorders. The findings suggest sex differences in the association between......The potential effects of alcohol intake upon the risk of psychiatric disorders have not often been investigated. The purpose of this study was to investigate, in a population sample, the association between self-reported amount of alcohol intake and the later risk of being registered in a Danish...

  8. Identification of the Risk Related to a Process on Hospital Emergency Service: a Case Study

    CERN Document Server

    Santos, Carlos; Ferreira, Carla; Tribolet, José

    2011-01-01

    This paper, framed in a vast investigation, describes the application of techniques and methodologies in Organizational Engineering connected to the associated risk to the processes developed in an Emergency Service of an important Portuguese Hospital. The transactions performed in an emergency service and the consequent risk identification (negative behaviour associated to those transactions) is done based on static and dynamic models, developed during the business modelling. Any non-trivial system is better portrayed trough a small number of reasonably independent models. From this point of view it is important to look at the systems from a "micro" perspective, which allows us to analyse the system at the transaction level. All processes have some associated risk (inherent risk). Its identification will be decisive for future analysis and for the consequent decision over the need, or not, to study internal control mechanisms. This decision will depend on the risk level that the organization considers accept...

  9. Subsite-Specific Dietary Risk Factors for Colorectal Cancer: A Review of Cohort Studies

    Directory of Open Access Journals (Sweden)

    Anette Hjartåker

    2013-01-01

    Full Text Available Objective. A shift in the total incidence from left- to right-sided colon cancer has been reported and raises the question as to whether lifestyle risk factors are responsible for the changing subsite distribution of colon cancer. The present study provides a review of the subsite-specific risk estimates for the dietary components presently regarded as convincing or probable risk factors for colorectal cancer: red meat, processed meat, fiber, garlic, milk, calcium, and alcohol. Methods. Studies were identified by searching PubMed through October 8, 2012 and by reviewing reference lists. Thirty-two prospective cohort studies are included, and the estimates are compared by sex for each risk factor. Results. For alcohol, there seems to be a stronger association with rectal cancer than with colon cancer, and for meat a somewhat stronger association with distal colon and rectal cancer, relative to proximal colon cancer. For fiber, milk, and calcium, there were only minor differences in relative risk across subsites. No statement could be given regarding garlic. Overall, many of the subsite-specific risk estimates were nonsignificant, irrespective of exposure. Conclusion. For some dietary components the associations with risk of cancer of the rectum and distal colon appear stronger than for proximal colon, but not for all.

  10. Plant sterol intakes and colorectal cancer risk in the Netherlands : cohort study on diet and cancer

    NARCIS (Netherlands)

    Normén, A.L.; Brants, H.A.M.; Voorrips, L.E.; Andersson, H.A.; Brandt, P.A. van den

    2001-01-01

    Background: Plant sterols in vegetable foods might prevent colorectal cancer. Objective: The objective was to study plant sterol intakes in relation to colorectal cancer risk in an epidemiologic study. Design: The study was performed within the framework of the Netherlands Cohort Study on Diet and C

  11. Study warns of radiation risk in medical imaging

    Science.gov (United States)

    Gwynne, Peter

    2009-10-01

    A study of a million US patients suggests that some who undergo medical imaging could be exposed to more ionizing radiation than those who work with radioactive materials in nuclear power plants. The study, reported in The New England Journal of Medicine (361 849), implies that current exposure to radiation from conventional X-ray equipment as well as computed tomography (CT) and positron-emission tomography (PET) scanners could lead to tens of thousands of extra cases of cancer in the US alone.

  12. Natural hazard risk perception of Italian population: case studies along national territory.

    Science.gov (United States)

    Gravina, Teresita; Tupputi Schinosa, Francesca De Luca; Zuddas, Isabella; Preto, Mattia; Marengo, Angelo; Esposito, Alessandro; Figliozzi, Emanuele; Rapinatore, Matteo

    2015-04-01

    Risk perception is judgment that people make about the characteristics and severity of risks, in last few years risk perception studies focused on provide cognitive elements to communication experts responsible in order to design citizenship information and awareness appropriate strategies. Several authors in order to determine natural hazards risk (Seismic, landslides, cyclones, flood, Volcanic) perception used questionnaires as tool for providing reliable quantitative data and permitting comparison the results with those of similar surveys. In Italy, risk perception studies based on surveys, were also carried out in order to investigate on national importance Natural risk, in particular on Somma-Vesuvio and Phlegrean Fields volcanic Risks, but lacked risk perception studies on local situation distributed on whole national territory. National importance natural hazard were frequently reported by national mass media and there were debate about emergencies civil protection plans, otherwise could be difficult to obtain information on bonded and regional nature natural hazard which were diffuses along National territory. In fact, Italian peninsula was a younger geological area subjected to endogenous phenomena (volcanoes, earthquake) and exogenous phenomena which determine land evolution and natural hazard (landslide, coastal erosion, hydrogeological instability, sinkhole) for population. For this reason we decided to investigate on natural risks perception in different Italian place were natural hazard were taken place but not reported from mass media, as were only local relevant or historical event. We carried out surveys in different Italian place interested by different types of natural Hazard (landslide, coastal erosion, hydrogeological instability, sinkhole, volcanic phenomena and earthquake) and compared results, in order to understand population perception level, awareness and civil protection exercises preparation. Our findings support that risks

  13. Exposure to diagnostic radiation and risk of breast cancer among carriers of BRCA1/2 mutations : retrospective cohort study (GENE-RAD-RISK)

    NARCIS (Netherlands)

    Pijpe, Anouk; Andrieu, Nadine; Easton, Douglas F.; Kesminiene, Ausrele; Cardis, Elisabeth; Nogues, Catherine; Gauthier-Villars, Marion; Lasset, Christine; Fricker, Jean-Pierre; Peock, Susan; Frost, Debra; Evans, D. Gareth; Eeles, Rosalind A.; Paterson, Joan; Manders, Peggy; van Asperen, Christi J.; Ausems, Margreet G. E. M.; Meijers-Heijboer, Hanne; Thierry-Chef, Isabelle; Hauptmann, Michael; Goldgar, David; Rookus, Matti A.; van Leeuwen, Flora E.

    2012-01-01

    Objective To estimate the risk of breast cancer associated with diagnostic radiation in carriers of BRCA1/2 mutations. Design Retrospective cohort study (GENE-RAD-RISK). Setting Three nationwide studies (GENEPSO, EMBRACE, HEBON) in France, United Kingdom, and the Netherlands, Participants 1993 femal

  14. Evaluation of a controlled, national collaboration study on a clinical pharmacy service of screening for risk medications

    DEFF Research Database (Denmark)

    Kjeldsen, Lene Juel; Clemmensen, Marianne Hald; Kronborg, Christian

    2014-01-01

    Background Risk medications are frequently associated with adverse events and hospitalisations. Objective To evaluate a risk medication screening service for in-patients at Danish hospitals. Setting Danish hospitals. Methods The study was designed as a controlled, prospective intervention study. ...

  15. Replicating the violence risk appraisal guide: a total forensic cohort study.

    Directory of Open Access Journals (Sweden)

    Astrid Rossegger

    Full Text Available INTRODUCTION: The performance of violence risk assessment instruments can be primarily investigated by analysing two psychometric properties: discrimination and calibration. Although many studies have examined the discrimination capacity of the Violence Risk Appraisal Guide (VRAG and other actuarial risk assessment tools, few have evaluated how well calibrated these instruments are. The aim of the present investigation was to replicate the development study of the VRAG in Europe including measurements of discrimination and calibration. METHOD: Using a prospective study design, we assessed a total cohort of violent offenders in the Zurich Canton of Switzerland using the VRAG prior to discharge from prisons, secure facilities, and outpatient clinics. Assessors adhered strictly to the assessment protocol set out in the instrument's manual. After controlling for attrition, 206 offenders were followed in the community for a fixed period of 7 years. We used charges and convictions for subsequent violent offenses as the outcomes. Receiver operating characteristic analysis was conducted to measure discrimination, and Sanders' decomposition of the Brier score as well as Bayesian credible intervals were calculated to measure calibration. RESULTS: The discrimination of the VRAG's risk bins was modest (area under the curve = 0.72, 95% CI = 0.63-0.81, p<0.05. However, the calibration of the tool was poor, with Sanders' calibration score suggesting an average assessment error of 21% in the probabilistic estimates associated with each bin. The Bayesian credible intervals revealed that in five out of nine risk bins the intervals did not contain the expected risk rates. DISCUSSION: Measurement of the calibration validity of risk assessment instruments needs to be improved, as has been done with respect to discrimination. Additional replication studies that focus on the calibration of actuarial risk assessment instruments are needed. Meanwhile, we recommend

  16. Mendelian randomization study of body mass index and colorectal cancer risk

    Science.gov (United States)

    Thrift, Aaron P.; Gong, Jian; Peters, Ulrike; Chang-Claude, Jenny; Rudolph, Anja; Slattery, Martha L.; Chan, Andrew T.; Locke, Adam E.; Kahali, Bratati; Justice, Anne E.; Pers, Tune H.; Gallinger, Steven; Hayes, Richard B; Baron, John A.; Caan, Bette J.; Ogino, Shuji; Berndt, Sonja I.; Chanock, Stephen J.; Casey, Graham; Haile, Robert W.; Du, Mengmeng; Harrison, Tabitha A.; Thornquist, Mark; Duggan, David J.; Le Marchand, Loïc; Lindor, Noralane M.; Seminara, Daniela; Song, Mingyang; Wu, Kana; Thibodeau, Stephen N.; Cotterchio, Michelle; Win, Aung Ko; Jenkins, Mark A.; Hopper, John L.; Ulrich, Cornelia M.; Potter, John D.; Newcomb, Polly A.; Hoffmeister, Michael; Brenner, Hermann; White, Emily; Hsu, Li; Campbell, Peter T.

    2015-01-01

    Background High body mass index (BMI) is consistently linked to increased risk of colorectal cancer (CRC) for men, whereas the association is less clear for women. As risk estimates from observational studies may be biased and/or confounded, we conducted a Mendelian randomization study to estimate the causal association between BMI and CRC. Methods We used data from 10,226 CRC cases and 10,286 controls of European ancestry. The Mendelian randomization analysis used a weighted genetic risk score, derived from 77 genome-wide association study identified variants associated with higher BMI, as an instrumental variable (IV). We compared the IV odds ratio (IV-OR) with the OR obtained using a conventional covariate-adjusted analysis. Results Individuals carrying greater numbers of BMI-increasing alleles had higher CRC risk (per weighted allele OR, 1.31; 95% confidence interval [CI], 1.10–1.57). Our IV estimation results support the hypothesis that genetically influenced BMI is directly associated with risk for CRC (IV-OR per 5 kg/m2, 1.50; 95% CI, 1.13–2.01). In the sex-specific IV analyses higher BMI was associated with higher risk of CRC among women (IV-OR per 5 kg/m2, 1.82; 95% CI, 1.26–2.61). For men, genetically influenced BMI was not associated with CRC (IV-OR per 5 kg/m2, 1.18; 95% CI, 0.73–1.92). Conclusions High BMI was associated with increased CRC risk for women. Whether abdominal obesity, rather than overall obesity, is a more important risk factor for men requires further investigation. Impact Overall, conventional epidemiologic and Mendelian randomization studies suggest a strong association between obesity and the risk of CRC. PMID:25976416

  17. A Prospective Study of Occupation and Prostate Cancer Risk

    NARCIS (Netherlands)

    Zeegers, M.P.A.; Friesema, I.H.M.; Goldbohm, R.A.; Brandt, P.A. van den

    2004-01-01

    A wide variety of occupations has been associated with prostate cancer in previous retrospective studies. Most attention has been paid to farming, metal working, and the rubber industry. Today, these results cannot be affirmed with confidence, because many associations could be influenced by recall

  18. Dietary acid load and risk of hypertension : the Rotterdam Study

    NARCIS (Netherlands)

    Engberink, Marielle F.; Bakker, Stephan J. L.; Brink, Elizabeth J.; van Baak, Marleen A.; van Rooij, Frank J. A.; Hofman, Albert; Witteman, Jacqueline C. M.; Geleijnse, Johanna M.

    2012-01-01

    Background: Mild metabolic acidosis, which can be caused by diet, may result in elevated blood pressure (BP). Objective: The objective was to examine whether dietary acid load was associated with incident hypertension in a cohort of older Dutch adults from the Rotterdam Study. Design: The analyses i

  19. Dietary acid load and risk of hypertension: The Rotterdam study

    NARCIS (Netherlands)

    M.F. Engberink (Marielle); S.J.L. Bakker (Stephan); E.J. Brink (Elizabeth); M.A. van Baak (Marleen); F.J.A. van Rooij (Frank); A. Hofman (Albert); J.C.M. Witteman (Jacqueline); J.M. Geleijnse (Marianne)

    2012-01-01

    textabstractBackground: Mild metabolic acidosis, which can be caused by diet, may result in elevated blood pressure (BP). Objective: The objective was to examine whether dietary acid load was associated with incident hypertension in a cohort of older Dutch adults from the Rotterdam Study. Design: Th

  20. Dietary acid load and risk of hypertension: The Rotterdam study

    NARCIS (Netherlands)

    Engberink, M.F.; Bakker, S.J.L.; Brink, E.J.; Baak, M.A. van; Rooij, F.J.A. van; Hofman, A.; Witteman, J.C.M.; Geleijnse, J.M.

    2012-01-01

    Background: Mild metabolic acidosis, which can be caused by diet, may result in elevated blood pressure (BP). Objective: The objective was to examine whether dietary acid load was associated with incident hypertension in a cohort of older Dutch adults from the Rotterdam Study. Design: The analyses i

  1. Polyphenols and disease risk in epidemiologic studies 1-4

    NARCIS (Netherlands)

    Arts, I.C.W.; Hollman, P.C.H.

    2005-01-01

    Plant polyphenols, a large group of natural antioxidants, are serious candidates in explanations of the protective effects of vegetables and fruits against cancer and cardiovascular diseases. Epidemiologic studies are useful for evaluation of the human health effects of long-term exposure to physiol

  2. Risk Factors Associated with Outcome in Liver Retransplantation : Multicentric Study

    NARCIS (Netherlands)

    Mattos, Rogerio O.; Linhares, Marcelo M.; Matos, Delcio; Adam, Rene; Bismuth, Henri; Castaing, Denis; Konietzko, Achim; Lerut, Jan; Porte, Robert J.; Neville, Jamieson; Azoulay, Daniel

    2015-01-01

    Background/Aims: To externally validate the predictive mathematical model of survival designed by Linhares et al. (2006). Methodology: This retrospective study was conducted on 217 individuals submitted to liver retransplantation from January 2000 to December 2008 in four European centers. The follo

  3. Ghana Fiasco Shows Risks of Faculty-Led Study Trips

    Science.gov (United States)

    Fischer, Karin

    2007-01-01

    This article illustrates the importance of preparation for professors who take students overseas. A University of Washington study-abroad program in Ghana that was cut short last summer after the medical evacuation of half of its participants highlights the potential hazards associated with programs led by individual faculty members who may lack…

  4. A new stratified risk assessment tool for whiplash injuries developed from a prospective observational study

    DEFF Research Database (Denmark)

    Kasch, Helge; Kongsted, Alice; Qerama, Erisela;

    2013-01-01

    OBJECTIVES: An initial stratification of acute whiplash patients into seven risk-strata in relation to 1-year work disability as primary outcome is presented. DESIGN: The design was an observational prospective study of risk factors embedded in a randomised controlled study. SETTING: Acute whiplash...... patients from units, general practitioners in four Danish counties were referred to two research centres. PARTICIPANTS: During a 2-year inclusion period, acute consecutive whiplash-injured (age 18-70 years, rear-end or frontal-end car accident and WAD (whiplash-associated disorders) grades I-III, symptoms...... and examined by a study nurse after 5 days; 605 were completed after 1 year. A risk score which included items of initial neck pain/headache intensity, a number of non-painful complaints and active neck mobility was applied. The primary outcome parameter was 1-year work disability. RESULTS: The risk score...

  5. A Study on the Thermomechanical Reliability Risks of Through-Silicon-Vias in Sensor Applications

    Directory of Open Access Journals (Sweden)

    Shuai Shao

    2017-02-01

    Full Text Available Reliability risks for two different types of through-silicon-vias (TSVs are discussed in this paper. The first is a partially-filled copper TSV, if which the copper layer covers the side walls and bottom. A polymer is used to fill the rest of the cavity. Stresses in risk sites are studied and ranked for this TSV structure by FEA modeling. Parametric studies for material properties (modulus and thermal expansion of TSV polymer are performed. The second type is a high aspect ratio TSV filled by polycrystalline silicon (poly Si. Potential risks of the voids in the poly Si due to filling defects are studied. Fracture mechanics methods are utilized to evaluate the risk for two different assembly conditions: package assembled to printed circuit board (PCB and package assembled to flexible substrate. The effect of board/substrate/die thickness and the size and location of the void are discussed.

  6. Risk factors for wheezing during infancy. A study of 5,953 infants

    DEFF Research Database (Denmark)

    Bisgaard, H; Dalgaard, P; Nyboe, J

    1987-01-01

    observed at least once during the first year of life, not in conjunction with pneumonia, epiglottitis or acute laryngitis. Logit analysis was used for the purpose of assessing the causal effect of environmental and other factors on the risk of wheezing among infants. The assessment of a risk factor......Risk factors for the development of wheezing during infancy were studied in 5,953 children. The data for the study were collected from a large prospective investigation of children born in 1959-61, who had attended a one-year follow-up examination. Wheezing was diagnosed when the symptom had been...... by means of regression technique, requires certain other variables to be included in the regression model. A general rule concerning inclusion of other variables has been formulated and applied to the above data. The study demonstrated that the risk of wheezing was affected by a number of factors...

  7. Recurrent wheezing in relation to environmental risk factors in infancy. A prospective study of 276 infants

    DEFF Research Database (Denmark)

    Halken, S; Høst, A; Husby, S

    1991-01-01

    to 3 months. Linear logistic regression analysis was used for the purpose of assessing the causal effect of environmental risk factors on the risk of recurrent episodes of wheezing before the age of 18 months. The study demonstrated that male sex and daily exposure to passive tobacco smoking were......Clinical course and environmental factors were recorded in a prospective study of 276 unselected infants followed from birth to the age of 18 months. The study was performed with a questionnaire at the age of 6 and 12 months and a physical examination at 18 months. Fifty-nine (21%) of the children...... significant risk factors with estimated odds ratios 1.9 and 2.4, respectively. Maternal tobacco smoking seemed to be associated with the highest risk. There was a tendency--though not significant--indicating that breastfeeding greater than or equal to 3 months had a protective effect.(ABSTRACT TRUNCATED...

  8. Handgrip strength cutoff for cardiometabolic risk index among Colombian children and adolescents: The FUPRECOL Study

    Science.gov (United States)

    Ramírez-Vélez, Robinson; Peña-Ibagon, Jhonatan Camilo; Martínez-Torres, Javier; Tordecilla-Sanders, Alejandra; Correa-Bautista, Jorge Enrique; Lobelo, Felipe; García-Hermoso, Antonio

    2017-01-01

    Evidence shows an association between muscular strength (MS) and health among young people, however low muscular strength cut points for the detection of high metabolic risk in Latin-American populations are scarce. The aim of this study was twofold: to explore potential age- and sex-specific thresholds of MS, for optimal cardiometabolic risk categorization among Colombian children and adolescents; and to investigate whether cardiometabolic risk differed by MS group by applying the receiver operating characteristic curve (ROC) cut point. MS was estimated by using a handle dynamometer on 1,950 children and adolescents from Colombia, using MS relative to weight (handgrip strength/body mass). A metabolic risk score was computed from the following components: waist circumference, triglycerides, HDL-c, glucose, and systolic and diastolic blood pressure. ROC analysis showed a significant discriminatory accuracy of MS in identifying the low/high metabolic risk in children and adolescents and in both genders. In children, the handgrip strength/body mass levels for a low metabolic risk were 0.359 and 0.376 in girls and boys, respectively. In adolescents, these points were 0.440 and 0.447 in girls and boys, respectively. In conclusion, the results suggest an MS level relative to weight for having a low metabolic risk, which could be used to identify youths at risk. PMID:28195167

  9. Estudos sobre estrutura, ciclo de vida e comportamento de Sardinella brasiliensis (Steindachner, 1879, na área entre 22ºS e 28ºS, Brasil: 3. morfologia e histologia de ovários e escala de maturidade Studies on the structure, life cycle and behaviour of Sardinella brasiliensis (Steindachner, 1879, in the region between 22ºS and 28ºS, Brazil: 3. Morphology and histology of ovaries and maturity scale

    Directory of Open Access Journals (Sweden)

    Victoria Judith Isaac-Nahum

    1983-01-01

    Full Text Available Uma melhor compreensão da dinâmica do processo reprodutivo de Sardinella brasiliensis e obtida através da associação de aspectos micro e macroscópicos das gonadas durante o ciclo sexual. O presente trabalho apresenta uma descrição das fases de desenvolvimento ovocitarias e dos estadios de maturidade dos ovarios de 119 fêmeas de S. brasiliensis, coletados na costa brasileira entre 22ºS e 28ºS. São descritas seis fases ovocitarias e duas estruturas derivadas, analisando-se as características citologicas das células germinativas durante o processo de maturação. Foram estabelecidos sete estadios: A (virgem, Bi (em início de maturação, Bf (em maturação avançada, Cf (maduro inicial, Cf (maduro desovado, D (es vaziado e R (em repouso, sendo discutida sua correspondência com outras es calas aplicadas as espécies.A better understanding of the reproductive process is obtained when histologic analysis of gonades is associated with macroscopic observations during the sexual cycles. This paper describes the developmental stages of the oocytes of the ovaries in 119 females of S. brasiliensis sampled along the Brazilian coast, between 22ºS and 28ºS. The cytologic characteristics of the germinative cells during the maturation process are given and six oocyte phases are described. Seven maturity stages are established: A (virgin, Bi (incipient maturation, Bf (advanced maturation, Ci (mature, Cf (ripe, D (spent and R (repose. These stages are compared to those presently used with respect to S. brasiliensis.

  10. A emenda da reeleição e a Lei de Responsabilidade Fiscal: impactos sobre ciclos políticos e performance fiscal dos Estados (1986-2002

    Directory of Open Access Journals (Sweden)

    Marcos Yamada Nakaguma

    2006-09-01

    Full Text Available O presente trabalho estuda o comportamento fiscal dos Estados brasileiros no período 1986-2002, analisando, em particular, o impacto de duas mudanças institucionais recentes, a Emenda da Reeleição e a Lei de Res-ponsabilidade Fiscal, sobre os ciclos políticos orçamentários e sobre a performance fiscal dos Estados. Os resultados obtidos apontam que a Emenda da Reeleição implicou a intensificação dos ciclos políticos, estimulando manipulações oportunistas durante o período eleitoral; a Lei de Responsabilidade Fiscal, por sua vez, constituiu um instrumento efetivo para o controle do endividamento e para a redução das despesas de custeio dos Estados. Constatou-se também que a amplitude dos ciclos políticos tem diminuído ao longo do tempo, fato que poderia ser atribuído ao aprendizado do eleitorado e à experiência adquirida com eleições sucessivas, que contribuem para elevar o nível de controle político, reduzindo, assim, a intensidade dos ciclos.This paper studies the fiscal behavior of Brazilian Federal States in the period 1986-2002, focusing, in particular, on the effects of two recent institutional changes, the "Reelection Amendment" and the "Fiscal Responsibility Law", on political budget cycles and on fiscal performance. The results provide evidence that the Reelection Amendment caused intensification in political cycles, stimulating opportunistic manipulations during the electoral period; and the Fiscal Responsibility Law constituted an effective instrument to control indebtedness and to reduce functionalism spending in States. The evidence also shows that the magnitude of the political cycles has been decreasing in time, a fact that could be attributed to the electorate’s learning and experience in successive elections, which contribute to increase the level of political control, so reducing the intensity of the cycles.

  11. Tea consumption and risk of stroke: a dose-response meta-analysis of prospective studies

    Institute of Scientific and Technical Information of China (English)

    Li SHEN; Liu-guang SONG; Hong MA; Chun-na JIN; Jian-an WANG; Mei-xiang XIANG

    2012-01-01

    Objective:To determine the association between tea consumption and the risk of stroke.Methods:We searched the PubMed database from January 1966 to March 2012 and reviewed reference lists of retrieved articles to identify relevant studies.Studies were included if they reported relative risks (RRs) and corresponding 95% confidence intervals (CIs) of stroke with respect to three or more categories of tea consumption.A random-effects model was used to combine the study-specific risk estimates.Results:Fourteen studies,consisting of 513 804 participants with a median follow-up of 11.5 years,were included in this meta-analysis.We observed a modest but statistically significant inverse association between tea consumption and risk of stroke.An increase of three cups/d in tea consumption was associated with a 13% decreased risk of stroke (RR 0.87; 95% CI,0.81-0.94).The decreased risk of stroke with tea consumption was consistent among most subgroups.Based on the three studies that provided results for stroke subtypes,tea consumption was also inversely associated with the risk of ischemic stroke (RR 0.76; 95% CI,0.69-0.84),but not cerebral hemorrhage (RR 0.96; 95% CI,0.82-1.11 ) or subarachnoid hemorrhage (RR 0.81 ; 95% CI,0.57-1.16).Conclusions:Tea consumption is associated with a decreased risk of stroke,particularly ischemic stroke.More well-designed,rigorously conducted studies are needed in order to make confident conclusions about the association between tea consumption and stroke subtypes.

  12. Underage drinking on saturday nights, sociodemographic and environmental risk factors: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Galasso Laura

    2011-07-01

    Full Text Available Abstract Background Excessive alcohol consumption in underage people is a rising phenomenon. A major proportion of the disease burden and deaths of young people in developed nations is attributable to alcohol abuse. The aim of this study was to investigate social, demographic and environmental factors that may raise the risk of Saturday night drinking and binge drinking among Italian school students. Methods The study was conducted on a sample of 845 Italian underage school students, by means of an anonymous, self-test questionnaire. Multivariate logistic regression was applied to identify independent risk factors for alcohol drinking and binge drinking. Ordered logistic regression was used to identify independent risk factors for harmful drinking patterns. Results The independent variables that confer a higher risk of drinking in underage students are older age classes, male sex, returning home after midnight, belonging to a group with little respect for the rules, or to a group where young people are not seen as leaders. The higher the perception of alcohol consumption by the group, the higher the risk. Spending time in bars or discos coincides with a two-fold or four-fold increase, respectively, in the risk of alcohol consumption. Conclusion Our findings show that certain environmental and social risk factors are associated with underage drinking. The most important role for preventing young people's exposure to these factors lies with the family, because only parents can exert the necessary control and provide a barrier against potentially harmful situations.

  13. 30. Cardiovascular risk factors burden in Saudi Arabia: The africa middle east cardiovascular epidemiological (ace study

    Directory of Open Access Journals (Sweden)

    A. Ahmed

    2016-07-01

    Full Text Available Limited data exit on the epidemiology of cardiovascular risk factors in Saudi Arabia particularly in relation to the differences between local citizens and expatriates. The aim of this analysis is to describe the current prevalence of cardiovascular risk factors among patients attending general practice clinics in Saudi Arabia. In a cross- sectional epidemiological study, the presence of cardiovascular risk factors (hypertension, diabetes, dyslipidaemia, obesity, smoking, and abdominal obesity was evaluated in stable adult outpatients attending primary care clinics in Saudi Arabia. Groups comparison were made between local Saudi patients and expatriates. A total of 550 participant were enrolled form different clinics in Saudi Arabia (71% were male, mean age was 43 ± 10 years. Nearly half of the study cohort had more than two cardiovascular risk factors (49.6%. Dyslipidemia had the highest prevalence (68.4%. Furthermore, prevalence of hypertension (47.5% vs. 31.4%, dyslipidaemia (75.2% vs. 55.1% and abdominal obesity (63.9% vs. 52.2% were higher among expatriates compare to Saudis (p-value < 0.001. This analysis clearly shows that there is a high prevalence of cardiovascular risk factors prevalence in Saudi population. In addition, a significant proportion of patients with risk factors have poor overall control. Programmed community based screening is needed for all cardiovascular risk factors in Saudi Arabia. Increased awareness and improved primary care services may decrease incidence of coronary artery disease and improve overall quality of life.

  14. A study on development of methodology and guidelines of risk based regulation for optimization of regulation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Hoon; Chang, Soon Hong; Kang, Kee Sik; Paek, Won Phil; Kim, Han Gon; Chang, Hyeon Seop [Korea Association for Nuclear Technology, Taejon (Korea, Republic of)

    1995-12-15

    This project consists of the three phase as follow : define the RBR(Risk Based Regulation) concept and analysis of state of art to RBR to NRC, EPRI etc., develop the application area and guideline of RBR to the selected area, develop the regulatory guideline with considering the plant specific conditions in detail. For the first year of this study elementary work for risk based regulation concept was analysed and performed as follows : state of the art of RBR research status, methodology establishment for usage of PSA(Probabilistic Safety Assessment), establishment of the methodology of risk based regulation, and application area for RBR.

  15. [Importance of the definition of urban zones in the study of cancer risk factors].

    Science.gov (United States)

    Pottier, D; Launoy, G; Le Coutour, X; Dugleux, G; Gignoux, M

    1989-01-01

    1446 cases of colorectal cancer have been collected in the Registry of digestive tract tumours in the "Department" of Calvados with the aim of studying the effect of residential location on cancer incidence. The risk-ratio was different in males and in females and between different types of urban areas. Using the urban category of "Zone de Peuplement Industriel ou Urbain" (ZPIU) increased the observed risk-ratio (1.6 for males, 1.2 for females), and enabled definition of homogeneous populations. This improved classification, thus allowed a more discriminating analysis of the effect of residential location on risk of cancer in both sexes.

  16. Folic Acid Supplementation in Pregnancy and the Risk of Pre-Eclampsia-A Cohort Study.

    Science.gov (United States)

    Wen, Shi Wu; Guo, Yanfang; Rodger, Marc; White, Ruth Rennicks; Yang, Qiuying; Smith, Graeme N; Perkins, Sherry L; Walker, Mark C

    2016-01-01

    This prospective cohort study designed to assess the effect of folic acid supplementation in pregnancy on the risk of preeclampsia (PE) took place in Ottawa, ON and Kingston, ON, Canada, from September 1, 2002 to August 31, 2008. Pregnant women, less than 20 weeks gestational age were recruited and delivered in the Ottawa region and the Kingston General Hospital. Demographic characteristics of the study participants and the patterns of supplementation of folic acid were described and occurrence of PE between women with folic acid supplementation during pregnancy and women without were compared. Multiple logistic regression was used in the estimation of the independent effect of supplementation of folic acid. Additional analyses assessing the effect of low RBC and serum folate and dose-response relationship were performed. Analyses were performed in all study participants, and then in high risk and low risk sub-groups, respectively. A total of 7,669 participants were included in the final analysis. Ninety five percent of the study participants were taking folic acid supplementation in early second trimester. The rate of PE was lower in the supplementation group than in the no supplementation group, and the difference was statistically significant in high risk women. Similar patterns of associations were observed in analysis by RBC and serum folate levels and in dose-response analysis. Folic acid supplementation in pregnancy may reduce PE risk in pregnant women, especially in those women with increased risk of developing PE.

  17. Certain modifiable risk factors in essential hypertension: a case-control study

    Directory of Open Access Journals (Sweden)

    Sunil M. Sagare, S. S. Rajderkar B. S. Girigosavi

    2011-01-01

    Full Text Available Essential hypertension accounts for 90% of all cases of hypertension. Though it is a one of major risk factors for cardiovascular diseases, it is a condition with its own risk factors. Overall prevalence of hypertension is increasing over the years in India (from 3.57% in 1977 to 20-30% after 1995. Considering the public health importance of ‘Essential Hypertension’ the present study was conducted. The objective was to study role of certain risk factors in essential hypertension. A case control study was conducted in rural township of Tasgaon; in Sangli district of Maharashtra during 2001-2002, to study role of certain modifiable risk factors in essential hypertension in 21-60 years age group. 165 cases of essential hypertension were selected by systematic random sampling from two private hospitals & O.P.D. of RHTC, Tasgaon and 330, age & sex matched controls were selected in the ratio of 1:2. A significant association was found between essential hypertension and various risk factors including smoking, its frequency and duration, alcoholic status, leisure time physical inactivity, restless sleep, BMI, mental stress, mixed diet and salt intake. Smoking of more than 10 cigarettes or bidi had 3.23 times risk of developing hypertension than smoking up to 10 cigarettes or bidi.

  18. Clustering of cardiovascular risk factors and carotid intima-media thickness: The USE-IMT study

    Science.gov (United States)

    Wang, Xin; den Ruijter, Hester M.; Anderson, Todd J.; Britton, Annie R.; Dekker, Jacqueline; Engström, Gunnar; Evans, Greg W.; de Graaf, Jacqueline; Grobbee, Diederick E.; Hedblad, Bo; Holewijn, Suzanne; Ikeda, Ai; Kauhanen, Jussi; Kitagawa, Kazuo; Kitamura, Akihiko; Kurl, Sudhir; Lonn, Eva M.; Lorenz, Matthias W.; Mathiesen, Ellisiv B.; Nijpels, Giel; Okazaki, Shuhei; Polak, Joseph F.; Price, Jacqueline F.; Rembold, Christopher M.; Rosvall, Maria; Rundek, Tatjana; Salonen, Jukka T.; Sitzer, Matthias; Stehouwer, Coen D. A.; Tuomainen, Tomi-Pekka; Peters, Sanne A. E.; Bots, Michiel L.

    2017-01-01

    Background The relation of a single risk factor with atherosclerosis is established. Clinically we know of risk factor clustering within individuals. Yet, studies into the magnitude of the relation of risk factor clusters with atherosclerosis are limited. Here, we assessed that relation. Methods Individual participant data from 14 cohorts, involving 59,025 individuals were used in this cross-sectional analysis. We made 15 clusters of four risk factors (current smoking, overweight, elevated blood pressure, elevated total cholesterol). Multilevel age and sex adjusted linear regression models were applied to estimate mean differences in common carotid intima-media thickness (CIMT) between clusters using those without any of the four risk factors as reference group. Results Compared to the reference, those with 1, 2, 3 or 4 risk factors had a significantly higher common CIMT: mean difference of 0.026 mm, 0.052 mm, 0.074 mm and 0.114 mm, respectively. These findings were the same in men and in women, and across ethnic groups. Within each risk factor cluster (1, 2, 3 risk factors), groups with elevated blood pressure had the largest CIMT and those with elevated cholesterol the lowest CIMT, a pattern similar for men and women. Conclusion Clusters of risk factors relate to increased common CIMT in a graded manner, similar in men, women and across race-ethnic groups. Some clusters seemed more atherogenic than others. Our findings support the notion that cardiovascular prevention should focus on sets of risk factors rather than individual levels alone, but may prioritize within clusters. PMID:28323823

  19. FDA-iRISK--a comparative risk assessment system for evaluating and ranking food-hazard pairs: case studies on microbial hazards.

    Science.gov (United States)

    Chen, Yuhuan; Dennis, Sherri B; Hartnett, Emma; Paoli, Greg; Pouillot, Régis; Ruthman, Todd; Wilson, Margaret

    2013-03-01

    Stakeholders in the system of food safety, in particular federal agencies, need evidence-based, transparent, and rigorous approaches to estimate and compare the risk of foodborne illness from microbial and chemical hazards and the public health impact of interventions. FDA-iRISK (referred to here as iRISK), a Web-based quantitative risk assessment system, was developed to meet this need. The modeling tool enables users to assess, compare, and rank the risks posed by multiple food-hazard pairs at all stages of the food supply system, from primary production, through manufacturing and processing, to retail distribution and, ultimately, to the consumer. Using standard data entry templates, built-in mathematical functions, and Monte Carlo simulation techniques, iRISK integrates data and assumptions from seven components: the food, the hazard, the population of consumers, process models describing the introduction and fate of the hazard up to the point of consumption, consumption patterns, dose-response curves, and health effects. Beyond risk ranking, iRISK enables users to estimate and compare the impact of interventions and control measures on public health risk. iRISK provides estimates of the impact of proposed interventions in various ways, including changes in the mean risk of illness and burden of disease metrics, such as losses in disability-adjusted life years. Case studies for Listeria monocytogenes and Salmonella were developed to demonstrate the application of iRISK for the estimation of risks and the impact of interventions for microbial hazards. iRISK was made available to the public at http://irisk.foodrisk.org in October 2012.

  20. Prevalence of myopia and its risk factors in urban school children in Delhi: the North India Myopia Study (NIM Study.

    Directory of Open Access Journals (Sweden)

    Rohit Saxena

    Full Text Available Assess prevalence of myopia and identify associated risk factors in urban school children.This was a cross-sectional study screening children for sub-normal vision and refractive errors in Delhi. Vision was tested by trained health workers using ETDRS charts. Risk factor questionnaire was filled for children with vision 11 years children (p 5 hours per day (p 2 hours / day (p 2 hours in a day.Myopia is a major health problem in Indian school children. It is important to identify modifiable risk factors associated with its development and try to develop cost effective intervention strategies.

  1. Typology of Perceived Risk in Foreign Traveling (Case Study: Inbound Tourists who Visited Isfahan

    Directory of Open Access Journals (Sweden)

    Amin Tslimi

    2013-01-01

    Full Text Available The successful of a tourism destination is depended on reinforcement of tourist’s encouraging factors and elimination of discouraging factors. Tourist’s perception of risk is a disincentive factor that influences tourist’s intention for traveling to that tourism destination. That is why this study has focused to identify and typology the perceived risks by inbound tourists who visited Isfahan. The statistical population of the study is inbound tourists who visited Isfahan during April and March of 2012. A sample of 300 tourists has been selected by convenience sampling method. A self-administrated questionnaire with 29 items has been used to gathering data. The results of exploratory factor analysis identified four types of risks which have been perceived by tourists who visited Isfahan. These include health, socio-cultural, life, and economic risks. Finally some of empirical suggestions have been offered.

  2. Multi-wave cohort study of sedentary work and risk of ischemic heart disease

    DEFF Research Database (Denmark)

    Møller, Simone Visbjerg; Hannerz, Harald; Hansen, Aase Marie

    2016-01-01

    OBJECTIVES: This study aimed to investigate whether sedentary work is a distinct risk factor for ischemic heart disease (IHD) when the effect of occupational sitting is disentangled from that of occupational physical activity. METHODS: Data on occupational sitting time and several covariates were...... status, no difference in risk of IHD was observed between sedentary and non-sedentary employees [hazard ratio (HR) 0.95, 95% confidence interval (95% CI) 0.78-1.16]. During 44 949 and 42 456 person-years of follow-up among men and and women, respectively, 1263 men and 1364 women purchased IHD......-related medication. No differences in risk were observed between sedentary and non-sedentary participants, either for men or women. A dose-response relationship between occupational sitting time and the risk of IHD was also not detected. CONCLUSIONS: This study could not confirm the hypothesis that sedentary work...

  3. Short-Term Effects of Screening for Cardiovascular Risk in the Deaf Community: A Pilot Study

    Directory of Open Access Journals (Sweden)

    J. V. Patel

    2011-01-01

    Full Text Available There is limited information on the risk of cardiovascular disease amongst the Deaf community. Given that the access of Deaf people to mainstream health promotion is likely to be hindered by language barriers, we were interested to assess the short-term impact of cardiovascular health promotion within this group. Using a pilot study we investigated changes in cardiovascular risk factors amongst Deaf people identified to be at high cardiovascular risk, who received standard health promotion by a medical team specializing in cardiovascular health promotion. The short-term impact of cardiovascular health promotion in this group did not reduce estimates of cardiovascular risk. The reasons for this are likely to relate to the design and delivery of health promotion to Deaf people, which deserves further study.

  4. Epidemiology of cardiovascular risk factors in Greece: aims, design and baseline characteristics of the ATTICA study

    Directory of Open Access Journals (Sweden)

    Chrysohoou Christina

    2003-10-01

    Full Text Available Abstract Background In an attempt to evaluate the levels of several cardiovascular risk factors in Greece we conducted a population-based health and nutrition survey, the "ATTICA study". In this work we present the design and the methodology of the study, as well as the status of various baseline characteristics of the participants. Methods From May 2001 to December 2002 we randomly enrolled 1514 adult men and 1528 adult women, stratified by age – gender (census 2000, from the greater area of Athens. More than 300 demographic, lifestyle, behavioral, dietary, clinical and biochemical variables have been recorded. Results Regarding the frequency of the classical cardiovascular risk factors we observed that 51% of men and 39% of women reported smokers (p Conclusions The prevalence of the common cardiovascular risk factors in our population seems high. As a consequence a considerable proportion of Greek adults are at "high-risk" for future cardiovascular events.

  5. Obesity and risk of colorectal cancer: a systematic review of prospective studies.

    Directory of Open Access Journals (Sweden)

    Yanlei Ma

    Full Text Available BACKGROUND: Mounting evidence indicates that obesity may be associated with the risk of colorectal cancer (CRC. To conduct a systematic review of prospective studies assessing the association of obesity with the risk of CRC using meta-analysis. METHODOLOGY/PRINCIPAL FINDINGS: Relevant studies were identified by a search of MEDLINE and EMBASE databases before January 2012, with no restrictions. We also reviewed reference lists from retrieved articles. We included prospective studies that reported relative risk (RR estimates with 95% confidence intervals (CIs for the association between general obesity [measured using body mass index (BMI] or central obesity [measured using waist circumference (WC] and the risk of colorectal, colon, or rectal cancer. Approximately 9, 000, 000 participants from several countries were included in this analysis. 41 studies on general obesity and 13 studies on central obesity were included in the meta-analysis. The pooled RRs of CRC for the obese vs. normal category of BMI were 1.334 (95% CI, 1.253-1.420, and the highest vs. lowest category of WC were 1.455 (95% CI, 1.327-1.596. There was heterogeneity among studies of BMI (P<0.001 but not among studies of WC (P=0.323. CONCLUSIONS: Both of general and central obesity were positively associated with the risk of CRC in this meta-analysis.

  6. Risk factors for prostate cancer: An hospital-based case-control study from Mumbai, India

    Directory of Open Access Journals (Sweden)

    B Ganesh

    2011-01-01

    Full Text Available Background : In India, prostate cancer is one of the five leading sites of cancers among males in all the registries. Very little is known about risk factors for prostate cancer among the Indian population. Objectives : The present study aims to study the association of lifestyle factors like chewing (betel leaf with or without tobacco, pan masala, gutka, smoking (bidi, cigarette, comorbid conditions, diet, body mass index (BMI, family history, vasectomy with prostate cancer. Materials and Methods : This an unmatched hospital-based case-control study, comprised of 123 histologically proven prostate ′cancer cases′ and 167 ′normal controls. Univariate and regression analysis were applied for obtaining the odds ratio for risk factors. Results : The study revealed that there was no significant excess risk for chewers, alcohol drinkers, tea and coffee drinkers, family history of cancer, diabetes, vasectomy and dietary factors. However, patients with BMI >25 (OR = 2.1, those with hypertension history (OR = 2.5 and age >55 years (OR = 19.3 had enhanced risk for prostate cancer. Conclusions : In the present study age, BMI and hypertension emerged as risk factors for prostate cancer. The findings of this study could be useful to conduct larger studies in a more detailed manner which in turn can be useful for public interest domain.

  7. How do women at increased, but unexplained, familial risk of breast cancer perceive and manage their risk? A qualitative interview study

    Directory of Open Access Journals (Sweden)

    Keogh Louise A

    2011-09-01

    Full Text Available Abstract Background The perception of breast cancer risk held by women who have not had breast cancer, and who are at increased, but unexplained, familial risk of breast cancer is poorly described. This study aims to describe risk perception and how it is related to screening behaviour for these women. Methods Participants were recruited from a population-based sample (the Australian Breast Cancer Family Study - ABCFS. The ABCFS includes women diagnosed with breast cancer and their relatives. For this study, women without breast cancer with at least one first- or second-degree relative diagnosed with breast cancer before age 50 were eligible unless a BRCA1 or BRCA2 mutation had been identified in their family. Data collection consisted of an audio recorded, semi-structured interview on the topic of breast cancer risk and screening decision-making. Data was analysed thematically. Results A total of 24 interviews were conducted, and saturation of the main themes was achieved. Women were classified into one of five groups: don't worry about cancer risk, but do screening; concerned about cancer risk, so do something; concerned about cancer risk, so why don't I do anything?; cancer inevitable; cancer unlikely. Conclusions The language and framework women use to describe their risk of breast cancer must be the starting point in attempts to enhance women's understanding of risk and their prevention behaviour.

  8. Feasibility of a cohort study on health risks caused by occupational exposure to radiofrequency electromagnetic fields

    DEFF Research Database (Denmark)

    Breckenkamp, Jürgen; Berg-Beckhoff, Gabriele; Münster, Eva

    2009-01-01

    BACKGROUND: The aim of this study was to examine the feasibility of performing a cohort study on health risks from occupational exposure to radiofrequency electromagnetic fields (RF-EMF) in Germany. METHODS: A set of criteria was developed to evaluate the feasibility of such a cohort study...

  9. Association Between the Mediterranean Diet and Cancer Risk: A Review of Observational Studies

    NARCIS (Netherlands)

    Verberne, L.D.M.; Bach-Faig, A.; Buckland, G.; Serra-Majem, L.

    2010-01-01

    The aim of this article was to summarize the evidence concerning the association between Mediterranean dietary pattern and cancer risk in observational epidemiological studies. All the studies that met the following criteria were reviewed: human cohort and case-control studies that examined the effe

  10. A prospective cohort study on antioxidant and folate intake and male lung cancer risk

    NARCIS (Netherlands)

    Voorrips, L.E.; Goldbohm, R.A.; Brants, H.A.M.; Poppel, G.A.F.C. van; Sturmans, F.; Hermus, R.J.J.; Brandt, P.A. van den

    2000-01-01

    Many studies have reported inverse associations between vegetable and fruit consumption and lung cancer risk. The aim of the present study was to elucidate the role of several antioxidants and folate in this relationship. In the Netherlands Cohort Study on Diet and Cancer, 58,279 men of ages 55-69 y

  11. Cardiovascular risk factors in women who had hypertensive disorders late in pregnancy : a cohort study

    NARCIS (Netherlands)

    Hermes, Wietske; Franx, Arie; van Pampus, Maria G.; Bloemenkamp, Kitty W. M.; Bots, Michiel L.; van der Post, Joris A.; Porath, Martina; Ponjee, Gabrielle A. E.; Tamsma, Jouke T.; Mol, Ben Willem J.; de Groot, Christianne J. M.

    2013-01-01

    OBJECTIVE: The purpose of this study was to determine cardiovascular risk factors in women with a history of hypertensive pregnancy disorders at term (HTP) 2.5 years after pregnancy. STUDY DESIGN: In a multicenter cohort study in The Netherlands from June 2008 through November 2010, cardiovascular r

  12. Ciclos orbitales jurásicos registrados en rocas sedimentarias aflorantes en la garganta de Breggia (Ticino-Suiza a partir de la suceptibilidad magnética

    Directory of Open Access Journals (Sweden)

    María Andrea Van Zele

    2012-06-01

    Full Text Available Algunas sucesiones estratigráficas sedimentarias se desarrollan en plataformas estables epicontinentales. Durante el Jurásico se formaron tales plataformas en el mar abierto denominado Tethys, y actualmente sus secuencias sedimentarias se localizan en Europa. A través de diferentes métodos se han reconocido ciclos orbitales en los sedimentos organogénicos precipitados en las plataformas del Mar de Tethys. Algunas de estas sucesiones registran ciclos orbitales terrestres denominados de precesión (de aproximadamente 20 ka, de oblicuidad (de aproximadamente 40 ka y de excentricidad (de aproximadamente 100 ka. En la garganta de Breggia sobre la base de la repetición rítmica (margas, calizas y lutitas también se determinaron dichos ciclos orbitales. El objetivo del presente trabajo es analizar si la susceptibilidad magnética de campo bajo medida en rocas jurásicas aflorantes en dicha garganta, es también un indicador de los ciclos mencionados. Para ello se compilaron 153 datos de susceptibilidad de un estudio preexistente que corresponden a las biozonas Uptonia jamesoni y Tragophyloceras ibex (aprox. 189 Ma a 187 Ma. Estas determinaciones se corrigieron debido a un incremento lineal observado, luego se calcularon los coeficientes de Fourier, el espectro de potencia y la variación del error cuadrático. De estos resultados se infiere que pueden haberse registrado los ciclos que corresponden a la precesión y oblicuidad del eje de rotación terrestre y la excentricidad de la órbita del planeta. El incremento lineal observado en la susceptibilidad podría deberse a un aumento gradual de minerales paramagnéticos y/o ferromagnéticos en la secuencia de las rocas sedimentarias analizadas. Es de destacar que en secuencias sedimentarias estudiadas en Dorset y Yorkshire (Inglaterra se reconoció un decrecimiento lineal de la relación 87Sr/86Sr para el lapso que corresponde a las biozonas Uptonia jamesoni y Tragophyloceras ibex. Este

  13. Effect of medroxy-progesterone acetate on follicular growth and endometrial cycloxygenase-2 (COX-2 expression during the bovine estrous cycle Efeito do acetato de medroxi-progesterona sobre o crescimento filicular e expressão endometrial de ciclooxigenase-2 (COX-2 durante o ciclo estral de bovinos

    Directory of Open Access Journals (Sweden)

    Valério M. Portela

    2010-07-01

    Full Text Available The objective of this study was to evaluate the effect of medroxy-progesterone acetate (MAP with or without estradiol benzoate (EB on follicular growth during the estrous cycle in cattle. In the first experiment, Hereford cows were synchronized with a synthetic analogue of PGF2 alpha and were treated with two different doses of MAP (250 or 500 mg with or without EB for 7 days starting on day 8 of the estrous cycle. Follicular growth was inhibited (PEste estudo teve como objetivo avaliar o efeito do acetato de medroxi-progesterona (MAP com ou sem benzoato de estradiol (BE sobre o crescimento folicular durante o ciclo estral bovino. No primeiro experimento, vacas da raça Hereford foram sincronizadas com um análogo sintético de PGF2á e tratadas com duas doses diferentes de MAP (250 ou 500mg, com ou sem EB, durante 7 dias, iniciando-se no oitavo dia do ciclo estral. Observou-se uma inibição do crescimento folicular (P<0,05 em todas as vacas, exceto no grupo controle e no grupo que recebeu 250mg de MAP sem BE. Os 75% dos animais não exibiu estro no momento da remoção do MAP, mas sim nos dias 21 e 22 do ciclo, demonstrando que os tratamentos não induziram cio. Para se determinar se o tratamento com BE alterou a sensibilidade endometrial à ocitocina e, assim, a cascata luteolítica, vacas multíparas pré-sincronizadas receberam 5mg de BE, seguidos, após 6 horas, de 50 UI de ocitocina (OT; n=9. Oito horas após a administração de BE, colheram-se fragmentos endometriais das vacas, nos dias 4, 13 e 17 do ciclo estral, mensurando-se a expressão gênica de COX-2 através de PCR. O BE aumentou os níveis de RNAm de COX-2 apenas no dia 17 do ciclo estral (P<0,05. Em conclusão, o MAP isolado ou associado a BE é capaz de suprimir o crescimento folicular bovino. Entretanto, o BE, na presença de MAP é ineficaz na indução da luteólise bovina, quando injetado no oitavo dia do ciclo estral.

  14. Low muscle strength is associated with metabolic risk factors in Colombian children: the ACFIES study.

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    Daniel Dylan Cohen

    Full Text Available PURPOSE: In youth, poor cardiorespiratory and muscular strength are associated with elevated metabolic risk factors. However, studies examining associations between strength and risk factors have been done exclusively in high income countries, and largely in Caucasian cohorts. The aim of this study was to assess these interactions in schoolchildren in Colombia, a middle income Latin American country. METHODS: We measured body mass index, body composition, handgrip strength (HG, cardiorespiratory fitness (CRF and metabolic risk factors in 669 low-middle socioeconomic status Colombian schoolchildren (mean age 11.52±1.13, 47% female. Associations between HG, CRF and metabolic risk factors were evaluated. RESULTS: HG and CRF were inversely associated with blood pressure, HOMA index and a composite metabolic risk score (p = 0.001, HOMA (β = -0.164; p = 0.005, triglycerides (β = -0.583; p = 0.026 and CRP (β = -0.183; p = 0.037 but not glucose (p = 0.698 or HDL cholesterol (p = 0.132. The odds ratios for having clustered risk in the weakest quartile compared with the strongest quartile were 3.0 (95% confidence interval: 1.81-4.95. CONCLUSIONS: In Colombian schoolchildren both poorer handgrip strength/kg body mass and cardiorespiratory fitness were associated with a worse metabolic risk profile. Associations were stronger and more consistent between handgrip and risk factors than between cardiorespiratory fitness and these risk factors. Our findings indicate the addition of handgrip dynamometry to non-invasive youth health surveillance programs would improve the accuracy of the assessment of cardio-metabolic health.

  15. A study on risk perception toward nuclear power operation in Taiwan

    Energy Technology Data Exchange (ETDEWEB)

    Lee Ciao-tzu; Hu Shiang-ling; Chang, Wushou P. [National Yang-Ming University, Taiwan (China)

    2000-05-01

    Currently, more conflicts appear between the public and government over the establishment of the 4th nuclear power plant in Taiwan. In order to improve risk management by the Society, understanding the risk perception of the public will be essential. A pilot study on the risk perception toward nuclear power operation and other current risks was conducted in summer of 1999. In addition to perception towards nuclear power operation, the survey evaluated several dimensions of health-related risks including smoking, chemical wastes, nuclear wastes, air transportation, AIDS, and food intoxication. The questionnaire was designed to be proceeded under systemic instruction and followed with self-filling. 57 (85.1%) of 67 respondents worked at the Taipei Metropolitan Rapid Transportation, including 62 male subjects (92.5%). 44 (69.8%) respondents favored building the 4th nuclear power plant in Taiwan. The acceptable distance between their houses and the nuclear power plant was 145.13 km in average, as compared with 400 km that of North and South of Taiwan. The mean expenses they are willing to pay to reduce the risk of the NPP is about US $7.73, 0.56% of their average income. However, the levels of risks toward nuclear power operation is significant higher than these for air transportation, smoking, and food intoxication. Government's spending is assumed more effective to reduce the threats from risks of nuclear power operation, rather than professional's or experts' effects. Besides, other related factors include levels of involuntary exposure to NP operation (p<0.001) and number of people potentially in danger (p<0.001). These 2 altitudes are positively correlated with the respondents' perceived risks. Different attitudes toward NP operation within these engineers, and those evaluated by others, are of great interest. Further evaluation will be conducted to compare the mechanism involved. We gratefully acknowledge financial support from the National

  16. Body mass index and risk of Parkinson's disease: a prospective cohort study.

    Science.gov (United States)

    Logroscino, Giancarlo; Sesso, Howard D; Paffenbarger, Ralph S; Lee, I-Min

    2007-11-15

    High body mass index has been associated with increased risk of several chronic diseases, including cardiovascular disease, and, recently, Alzheimer's disease. There are few data on the association of body mass index with Parkinson's disease, and results have been inconsistent. The authors conducted a prospective study among 10,812 men in the Harvard Alumni Health Study, followed from 1988 to 1998 (mean age at baseline: 67.7 years), to test the hypothesis that body mass index is associated with Parkinson's disease risk. Among 106 incident cases of Parkinson's disease, body mass index at baseline was not associated with Parkinson's disease risk (for body mass index or =25.0 kg/m2: multivariate relative risks = 1.51 (95% confidence interval: 0.95, 2.40), 1.00 (referent), and 0.86 (95% confidence interval: 0.53, 1.41)). The authors had information on body mass index during late adolescence, when men entered college; this was unrelated to Parkinson's disease risk as well. Subjects who lost at least 0.5 units of body mass index per decade between college entry and 1988 had a significantly increased Parkinson's disease risk, compared with men having stable body mass index (multivariate relative risk = 2.60, 95% confidence interval: 1.10, 6.10). The authors conclude that body mass index is unrelated to Parkinson's disease risk and speculate that the observation of increased risk with body mass index loss since late adolescence may reflect weight loss due to Parkinson's disease that preceded clinical diagnosis.

  17. A Case-Control Study of Risk Factors for Bovine Brucellosis Seropositivity in Peninsular Malaysia

    OpenAIRE

    Mukhtar Salihu Anka; Latiffah Hassan; Siti Khairani-Bejo; Mohamed Abidin Zainal; Ramlan Bin Mohamad; Annas Salleh; Azri Adzhar

    2014-01-01

    Bovine brucellosis was first reported in Peninsular Malaysia in 1950. A subsequent survey conducted in the country revealed that the disease was widespread. Current knowledge on the potential risk factors for brucellosis occurrence on cattle farms in Malaysia is lacking. Therefore, we conducted a case-control study to identify the potential herd-level risk factors for bovine brucellosis occurrence in four states in the country, namely Kelantan, Pahang, Selangor and Negeri Sembilan. Thirty-fiv...

  18. COMPARATIVE STUDY OF RISK FACTORS OF TYPE-II DIABETES IN RURAL AND URBAN POPULATION

    OpenAIRE

    Ch. Kiranmai; Sukhes; Rama Krishna; Preethi; Aruna

    2014-01-01

    : A study of effect of various risk factors on Type–II diabetes in Urban and rural population. Generally Indians seems to have great tendency to develop diabetes mellitus. In addition to this, unhealthy food habits, lack of physical activity, diabetic family history, age, obesity, smoking & alcoholism are the other causes for diabetes mellitus. AIM: To analyze the impact of different risk factors on Type – II diabetes in urban and rural population. METHODS: Total 160 subjects ...

  19. Caffeinated Coffee, Decaffeinated Coffee and Endometrial Cancer Risk: A Prospective Cohort Study among US Postmenopausal Women

    OpenAIRE

    Reeves, Katherine W.; Elizabeth Bertone-Johnson; Nicole Luisi; Raji Balasubramanian; Ayush Giri; Sturgeon, Susan R.

    2011-01-01

    There is plausible biological evidence as well as epidemiologic evidence to suggest coffee consumption may lower endometrial cancer risk. We evaluated the associations between self-reported total coffee, caffeinated coffee and decaffeinated coffee, and endometrial cancer risk using the Women’s Health Initiative Observational Study Research Materials obtained from the National Heart, Lung, and Blood Institute Biological Specimen and Data Repository Coordinating Center. Our primary analyses inc...

  20. Risk of pre-eclampsia in first and subsequent pregnancies: prospective cohort study

    OpenAIRE

    2009-01-01

    Objective: To investigate whether pre-eclampsia is more common in first pregnancies solely because fewer affected women, who presumably have a higher risk of recurrence, go on to have subsequent pregnancies. Design: Prospective cohort study. Setting: Swedish Medical Birth Register. Participants: 763 795 primiparous mothers who had their first births in Sweden, 1987-2004. Main outcome measures: Pre-eclampsia. Results: The risk of pre-eclampsia was 4.1% in the first pregnancy and 1.7% in later ...