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Sample records for cicatrix

  1. STIMULATION OF CICATRIX AND EPITHELIUM MAKING PROCESES, BY USE OF SOME AROMATIC PLANT EXTRACTS

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    O. NEGREA; O. LIVIU; Mihalca, A; V. MICLĂUS

    2013-01-01

    This experiment has as purpose an evaluation of cicatrix stimulation and healing capacity of some accidental wounds produced by different body regions to a livestock of 20 horses, young stock and adult animals, during the year 2007, by local treatment with hydrogel ointment prepared from 8 medicinal plants, namely Echinaceea palida, Calendula officinalis, Populus nigra, Symphytum officinalis, Arnica montana, Thuja occidentalis, Veronica officinalis and Salvia officinalis. To the end of experi...

  2. STIMULATION OF CICATRIX AND EPITHELIUM MAKING PROCESES, BY USE OF SOME AROMATIC PLANT EXTRACTS

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    O. NEGREA

    2013-12-01

    Full Text Available This experiment has as purpose an evaluation of cicatrix stimulation and healing capacity of some accidental wounds produced by different body regions to a livestock of 20 horses, young stock and adult animals, during the year 2007, by local treatment with hydrogel ointment prepared from 8 medicinal plants, namely Echinaceea palida, Calendula officinalis, Populus nigra, Symphytum officinalis, Arnica montana, Thuja occidentalis, Veronica officinalis and Salvia officinalis. To the end of experiment, the best results, in epithelium making and wound contraction, were obtained with Calendule officinalis ointment, which has shortened this stage with 6 days, comparatively to witness wounds and those treated with Veronica officinalis, with 5 days facing to Thuja occidentalis and Salvia officinalis, with 4 days facing to Symphytum officinalis and Arnica montana , with 2 days facing Populus nigra and one day facing to Echinaceea palida.

  3. 疤痕止痒软化膏对烧伤创面致痒介质影响的动物实验研究%Experimental study on effect of cicatrix antipruritic ointment on burn wounds itch mediators

    Institute of Scientific and Technical Information of China (English)

    易先锋; 卢根香; 宋春红; 钟伟湘; 童钟

    2012-01-01

    Objective To observe the effects of cicatrix antipruritic ointment on burn wounds itch mediators of the rabbit. Methods The contents of nerve endings, substance P, mast cell, histamine and serotonin of the rabbits burn wounds treated by cicatrix antipruritic ointment in different time were determined by using Cajal Pyridine silver staining, immunohistochemical techniques and the computer image processing technique, we finished the study. Detecting the. Results The differences of nerve endings and SP content between two groups at the different time periods of the bum wounds were insignificant(P > 0.01). The differences between two groups were significant (P <0.01). Conclusion There is a certain impact of Antipruritic ointment for cicatrix preparation on the rabbit burn wounds itch mediators. Early intervention of bum wounds early period for bum itching is a method can be considered.%目的 研究疤痕止痒软化中药膏剂对家兔烧伤创面致痒介质的影响.方法 通过Cajal吡啶银染法,免疫组织化学技术,计算机辅助图像分析技术检测使用疤痕止痒软化膏后家兔烧伤创面及创面愈合后不同时间组织神经末梢数量,(substanceP,SP)P物质,肥大细胞数目,组胺及5-羟色胺的多少.结果 家兔使用疤痕止痒膏在烧伤创面及烧伤愈合后的创面不同时间点上部分毁损皮肤的神经末梢整体结构及数量实验组与对照组比较差异性不大.用药后家兔深Ⅱ°烧伤创面及烧伤愈合后创面组织不同时间点中组织SP含量与对照组比较差异性不大大(P>0.01).用药后实验组脱颗粒的肥大细胞数目明显少于对照组(P<0.01).实验组的组织胺及5-色胺量与对照组比较有明显差异(P<0.01).结论 疤痕止痒软化膏对家兔烧伤创面致痒介质有一定的影响,从烧伤创面早期就开始用药物进行烧伤瘙痒的干预是一条可以考虑的方法.

  4. [Cutaneous cicatrix: natural course, anomalies and prevention].

    Science.gov (United States)

    Bardot, J

    1994-09-01

    Improving scar quality has become a major concern for surgeons. Although good skin suturing is of primordial important, the healing process varies greatly from one patient to another and the risk of hypertrophic or keloid scar evolution is currently unpredictable. Local massage and above all post-operative compression using compressive garments and sheets of silicon are an efficient methods of counteracting the proliferative phase which occurs during the first few months. In severe cases, particularly in burn patients, high-pressure springwater hydrotherapy to reduce scar contracture has proved to be effective. The current trend is to decrease the risk of bad scars in the immediate post-traumatic, post-operative stage in order to obtain the best possible scar initially and thus avoid revision surgery.

  5. The genus Codium (Chlorophyta, Codiales) from Kenya, Tanzania (Zanzibar) and the Seychelles

    OpenAIRE

    Van den heede, C.; Coppejans, E.

    1996-01-01

    Descriptions and illustrations are provided of 14 species. Codium, collected in Kenya, Zanzibar and the Seychelles Archipelago from 1985 to 1994 of C. arabicum, C. cicatrix, C. duthieae, C. dwarkense, C. extricatum, C. geppiorum, C. lucasii, C. ovale, C. pocockiae, C. prostratum, C. repens, C. taylorii, C. vaughanii and C. sp. Codium cicatrix and C. repens are new records for Kenya; C. extricatum, C. lucasii and C. pocockiae are new for Tanzania; C. arabicum, C. cicatrix, C. extricatum, C. va...

  6. Systematics of Australian Thrasorinae (Hymenoptera: Cynipoidea: Figitidae) with a description of Mikeiinae, new subfamily, and two new genera and three new species

    Science.gov (United States)

    A new systematics of Australian Thrasorinae is proposed herein. The genus Mikeius is transferred from Thrasorinae to Mikeiinae Paretas-Martínez & Pujade-Villar n. subf and M. clavata Pujade-Villar & Restrepo-Ortiz n. sp. is described. Two new genera of Thrasorinae are erected: Cicatrix Paretas-Martí...

  7. Surgical Removal of lipoma from an area with tattooed skin

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    Francesco Inchingolo, Marco Tatullo, Fabio M. Abenavoli, Massimo Marrelli, Alessio D. Inchingolo, Roberto Corelli, Andrea Servili, Angelo M. Inchingolo, Gianna Dipalma

    2010-01-01

    Full Text Available The presence of tattoos on the skin of people of all ages is on the rise. On occasion, the tattoo is in close proximity to an area which has to undergo a surgical operation, therefore why not using the tattoo itself to cover the cicatrix?The case we treated was that of a 39 year old female who, for a couple of years, had a large lipoma on her right shoulder which she never treated because it was beneath a large tattoo. During the surgical treatment of the lipoma, we followed the exact lines of the tattoo itself thus obtaining precise access for lipoma removal which minimized visible post operative cicatrix while maintaining the original tattoo design.No similar case was found in literature.

  8. Scar prevention and remodeling: a review of the medical, surgical, topical and light treatment approaches.

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    Kerwin, Leonard Y; El Tal, Abdel Kader; Stiff, Mark A; Fakhouri, Tarek M

    2014-08-01

    Cosmetic, functional, and structural sequelae of scarring are innumerable, and measures exist to optimize and ultimately minimize these sequelae. To evaluate the innumerable methods available to decrease the cosmetic, functional, and structural repercussions of scarring, pubMed search of the English literature with key words scar, scar revision, scar prevention, scar treatment, scar remodeling, cicatrix, cicatrix treatment, and cicatrix remodeling was done. Original articles and reviews were examined and included. Seventy-nine manuscripts were reviewed. Techniques, comparisons, and results were reviewed and tabulated. Overall, though topical modalities are easier to use and are usually more attractive to the patient, the surgical approaches still prove to be superior and more reliable. However, advances in topical medications for scar modification are on the rise and a change towards medical treatment of scars may emerge as the next best approach. Comparison studies of the innumerable specific modalities for scar revision and prevention are impossible. Standardization of techniques is lacking. Scarring, the body's natural response to a wound, can create many adverse effects. At this point, the practice of sound, surgical fundamentals still trump the most advanced preventative methods and revision techniques. Advances in medical approaches are available, however, to assist the scarring process, which even the most advanced surgical fundamentals will ultimately lead to. Whether through newer topical therapies, light treatment, or classical surgical intervention, our treatment armamentarium of scars has expanded and will allow us to maximize scar prevention and to minimize scar morbidity.

  9. Mechanical oscillopsia after lower eyelid blepharoplasty with fat repositioning.

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    Thinda, Sumeer; Vaphiades, Michael S; Mawn, Louise A

    2013-03-01

    Blepharoplasty with fat repositioning is a technique used to fill the tear trough in the aging lower eyelid. We describe a patient who underwent transcutaneous lower eyelid blepharoplasty with fat repositioning who subsequently developed mechanical oscillopsia in the right eye exacerbated by facial movement. Surgical exploration revealed cicatrix between the inferior oblique muscle and the anterior superficial musculoaponeurotic system. Excision of the scar bands led to immediate amelioration of symptoms. When performing blepharoplasty with fat repositioning, it is essential to be aware of the anatomic location of the inferior oblique in the anterior inferomedial orbit to avoid incarceration of this muscle. PMID:23222371

  10. Radiation therapy for the prevention of postoperative and traumatic complications

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    Kishkovskij, A.N.; DudareV, A.L. (Voenno-Meditsinskaya Akademiya, Leningrad (USSR))

    1983-05-01

    An analysis of the results of radiation therapy of 587 patients with postoperative and traumatic complications has shown that special ..gamma..-therapy used at early time following trauma or surgical intervention, with the first clinical signs of an incipient inflammatory process (the so-called ''anticipating'' irradiation), makes it possible to avoid the development of serious postoperative, post-traumatic complications: wound suppuration, fistulas, secondary parotitis, postamputation pain syndrome, ''needle'' osteomyelitis, keloid cicatrix, skin graft rejection, etc. In the author opinion, this promising trend in radiotherapy of nontumorous diseases is worth a wider using in clinical practice.

  11. 浅表脂肪瘤样痣1例%A Case of Nevus Lipomatosus Superficialis

    Institute of Scientific and Technical Information of China (English)

    李俊峰; 徐佳; 李鑫; 姜秋霞; 刘杰; 马俊平

    2012-01-01

    A 10-year-old girl had presented with papulae and plaque on the sacrococcygeal region for 9 years. Physical examination showed clustered soft papulae on die aacrococcygeal region with amber color,and anastomosis inequality of size. Two cicatrix were appearanced on center of erylhra with 1.0cm × 1.5cm. Histopathological examination showed hyperkeratinizalion, stratum spinosum hyperplasia, abnormal position adipocytes distributed in lamina superficialis and intercellular layer of dermis. A diagnosis of nevus lipomatosus superfi-cialis was established.%患者女,10岁.骶尾部丘疹、融合性斑块9年余.皮肤科情况:骶尾部可见簇集分布的米粒大淡黄色丘疹,质地柔软,融合成多处大小不等斑块或斑片,皮疹中央可见2处1.0cm×1.5cm大瘢痕增生.皮损组织病理示:表皮轻度角化过度,棘细胞层增生,真皮浅中层胶原束间可见成群分布异位脂肪细胞.诊断:浅表脂肪瘤样痣.

  12. [Rectal stenosis due to Schnitzler metastasis following surgery for gastric cancer--a case successfully treated with TS-1 and CDDP combination chemotherapy].

    Science.gov (United States)

    Niinobu, Takahiro; Nakagawa, Sumiko; Itani, Yutaka; Nishikawa, Yasuaki; Amano, Masahiro; Higaki, Naozumi; Hayashida, Hiroto; Sakon, Masato

    2005-10-01

    The patient, a 40-year-old woman, underwent total gastrectomy and excision of the pancreatic tail, spleen and gallbladder for gastric cancer in September 2000. The lesion was judged to be P1, SE, H0, N2 and Stage IV and the patient was managed on a regular schedule as an outpatient. In September 2004, she passed blood-stained feces and rectal palpation detected a hard nodule at the anterior rectal wall. A fiber optic examination of the sigmoid colon detected an ulcerous lesion with a hemorrhage at the anterior rectal wall. A biopsy revealed the lesion to be Group V poorly differentiated adenocarcinoma. Starting in October 2004, 100 mg/day of TS-1 was administered for 3 weeks; intravenous drip infusion of 100 mg/body of CDDP was conducted in the second week for a period of 24 hours. After 3 courses of this regimen, a fiber optic examination of the colon conducted in February 2005 no longer detected the rectal tumor, leaving only a cicatrix. Upon a CT examination, the para-aortic lymph nodes that had been enlarged were notably reduced in size and an improvement was eminent in the hypertrophic rectal wall. The patient no longer experienced constipation or melena. Her clinical course is being observed while an oral administration of 100 mg/day of TS-1 continues. PMID:16315933

  13. Radiation to the breast. Complications amenable to surgical treatment

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    Bostwick, J.; Stevenson, T.R.; Nahai, F.; Hester, T.R.; Coleman, J.J.; Jurkiewicz, M.J.

    1984-10-01

    Major complications of radiation directed to the breast, axilla, and mediastinum were treated in 54 patients from 1974 to 1983. A classification of these complications facilitates both an understanding of the pattern of injury and the development of a treatment plan. Classification: I. Breast necrosis; II. Radionecrosis and Chest Wall Ulceration; III. Accelerated Coronary Atherosclerosis with Median Sternotomy Wound Failure After Coronary Revascularization; IV. Brachial Plexus Pain and Paresis; V. Lymphedema and Axillary Cicatrix; VI. Radiation-induced Neoplasia. The treatment has evolved during the 10-year study period to excision of the necrotic wound, including any tumor, and closure with a transposed muscle or musculocutaneous flap of latissimus dorsi (II, III, V) or rectus abdominis (I, II, VI). This strategy reflects a change from primary use of the omentum during the first years of the study. The vascularity, oxygen and antibiotic delivery of these muscle and musculocutaneous flaps promote wound healing, usually with one operation. The transfer of these muscles has not caused significant functional deficits.

  14. Applying the laser beam for reconstruction of the upper airway

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    Kukwa, Andrzej; Tulibacki, Marek P.; Wojtowicz, Piotr; Dudziec, Katarzyna; Oledzka, Iwona

    2000-11-01

    The authors present their own experience in restoration of the upper airway using a different source of high power laser. There are many patients with a stricture of the upper airway. One of the most common cause insufficiency of this is nosal polyps. Surgical treatment of polyps till now is not sufficiently effective. For this reason we work out a Nd:YAG laser applying technique that let us to reduce a hospitalization time with elongation of an asymptotic period of our patients. Nd:YAG energy we apply for conchoplasty benefiting of its profound coagulation as a distinctive role. This type of laser is very useful in removing of granulation tissue from different areas of the upper airway. Other applications of Nd:YAG laser in our hands is very useful for: coagulation of vessels in Kisselbach area, especially in Rendou-Osler's diseases, resection of the nosal Septo-turbinate adhesions, treatment of hemangiomas and small papillomas in nasal cavity, diminishing of the hypertrophied mucosa in the nasopharyngeal space as well as, reduction of the uvula and soft palate in OSAS patients. In our department we use a Nd:YAG for treatment of precancerous and early stages of cancer and for a palliation procedures in an advanced cancer infiltration in mouth, pharynx and laryngeal region. For treatment removing of cicatrix tissue in a larynx and trachea we use to use a Holm: YAG laser their very superficial penetration of tissues is used for a coagulation of small vessels too let us to resect it without bleeding from a bony and mucosa tissue, as a fragments maxillary sinus wall, nosal septum crest or spine with resection of the posterior pole of a turbinate. Both laser are conveyed by fiberoptic, to reach a pathological changes in many plans, places for this reason we are able to continuously work on a new its applications.

  15. Region-oriented and staged treatment strategy in reconstruction of severe cervical contracture.

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    Xusong Luo

    Full Text Available Severe cervical contracture after burns causes obvious impairment of neck movement and the aesthetic silhouette. Although various surgical techniques for treatment have been described, there is not a definitive strategy to guide treatment. Over the past 6 years, we have been utilizing a region-oriented and staged treatment strategy to guide reconstruction of severe cervical contracture. Satisfactory results have been achieved with this strategy.The first stage of treatment focuses on the anterior cervical region and submental region. Procedures include cicatrix resection, contracture release, division and elevation of the platysma to form two platysma flaps, and skin grafting. Three to six months later, the second stage treatment is performed, which localize to the mental region. This includes scar resection, correction of the lower lip eversion, and reconstruction with free (parascapular skin flap. Three subtypes of cervicomental angle that we proposed were measured as quantitative tool for evaluation of the reconstruction.24 patients who completed the treatment were reviewed. By the 3rd postoperative month, their CM angles changed significantly: the soft tissue CM angle was reduced from 135.0° ± 17.3° to 111.1° ± 11.3°, the osseous CM angle increased from 67.1° ± 9.0° to 90.5° ± 11.6° and the dynamic CM angle increased from 21.9° ± 8.7° to 67.4° ± 13.1°. 22 in 24 (91.7% of these patients gained notable improvement of cervical motion and aesthetic contour.Our results suggest that the region-oriented and staged treatment strategy can achieve satisfactory functional and aesthetic results, combining usage of both skin graft and skin flap while minimizing the donor site morbidity.

  16. 颈阔肌瓣双向翻转在颈部严重瘢痕增生挛缩整复中的应用%Application of Two Directions Folding of Platysma Flap in Reconstruction for Contracture Deformity of Severe Cervical Scar

    Institute of Scientific and Technical Information of China (English)

    纪赓; 王守宝; 罗旭松; 李罗珠; 杨军

    2012-01-01

    Objective To introduce a surgical technique of two directions folding of platysma flap in reconstruction for cervical cicatrix contracture. Methods Fifteen patients with cervical scar contracture were treated with split to full thickness skin grafts, combined with platysma flap double directions folding that deepen cervico-mandibular angle and cover scar section. Results AH skin grafts survived and natural cervical appearance with smooth transition and improved activity were achieved. Conclusion The new technique of two directions folding of platysma flap was proved to be effective in the treatment of cervical scar contracture.%目的 介绍颈阔肌瓣双向翻转技术在修复颈部瘢痕挛缩中的应用.方法 针对15例烧伤后颈部瘢痕挛缩患者,利用颈阔肌瓣双向翻转技术加深颏颈角并形成缓和自然的颈胸部过渡,颈部创面移植厚中厚皮片或全厚皮片.结果 15例患者皮片均成活良好,颏颈角明显,颈部自然曲线和活动度基本恢复,效果满意.结论 颈阔肌瓣双向翻转技术能有效解决颈部瘢痕挛缩,具有进一步深入探讨和推广应用的价值.

  17. Dacryocystorhinostomy ostium: parameters to evaluate and DCR ostium scoring

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    Ali MJ

    2014-12-01

    Full Text Available Mohammad Javed Ali,1 Alkis James Psaltis,2 Peter John Wormald2 1Dacryology Service, L V Prasad Eye Institute, Hyderabad, Telangana, India; 2Department of Surgery–Otorhinolaryngology, Head and Neck Surgery, The University of Adelaide, Adelaide, SA, Australia Aim: This study aims to provide a systematic protocol for the evaluation of a dacryocystorhinostomy (DCR ostium and to propose a scoring system to standardize the assessment.Methods: Retrospective evaluation of 125 consecutive lacrimal ostia post-DCR was performed. Medical records were screened, and photographs and videos were assessed to note the details of various ostial parameters. The major time points in evaluation were 4 weeks, 6 weeks, 3 months, and 6 months post-DCR. The ostia were defined and parameters like shape, size, location, and evolution of ostium were noted. Evaluation parameters were defined for internal common opening (ICO, ostium stents, and ostium granulomas. Ostium cicatrix and synechiae were graded based on their significance. Surgical success rates were computed and ostium characteristics in failed cases were studied.Results: A total of 125 ostia were evaluated on the aforementioned ostium parameters. Because five ostia showed a complete cicatricial closure with no recognizable features, the remaining 120 ostia were studied. The ostium location was anterior to the axilla of middle turbinate in 85.8% (103/120 of the cases. Moreover, 76.6% (92/120 of the ostia were circular to oval in shape, with a shallow base. The ostium size was >8×5 mm in 78.3% (94/120 of the cases. The ICO was found to be located in the central or paracentral basal area in 75.8% (91/120. The anatomical and functional success rates achieved were 96% and 93.6%, respectively. All the five cases with anatomical failures showed a complete cicatrization and the ICO movements were poor in all the three cases of functional failure.Conclusion: The article attempts to standardize the postoperative

  18. Development of a Best Evidence Statement for the Use of Pressure Therapy for Management of Hypertrophic Scarring.

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    Sharp, Patricia A; Pan, Brian; Yakuboff, Kevin P; Rothchild, Dawn

    2016-01-01

    Pressure therapy has been considered standard, first-line intervention for the treatment of hypertrophic scars since its introduction in the 1960s. Although widely used, this scar management technique has historically been based on a wide array of anecdotal evidence as opposed to strong scientific support. Evidence has become more prevalent in recent years, necessitating a synthesis to develop an evidence-based clinical guideline. The clinical question was asked, "Among individuals with or at risk to develop active hypertrophic scars, does treatment with pressure therapy improve aesthetic and functional outcomes?" An evidence-based practice project was completed with aims to synthesize relevant literature to determine recommendations for the use of pressure therapy in individuals at risk for hypertrophic scars. A systematic search of the literature was conducted for the dates January 1950 to February 2014 of the following databases: MEDLINE, CINAHL, Cochrane Database for Systematic Reviews, Burntherapist.com, Cochrane Libraries, Ebsco, Google Scholar, OT Seeker, Ovid, MedLine, PEDro.org, Pubmed.gov, Pubmed Clinical Queries, and hand search of relevant articles through use of reference lists. Search terms included scar, hypertroph*, pressure therapy, compression therapy, pressure garment, burn, scald, trauma as well as MeSH terms cicatrix and hypertrophic. Articles were reviewed in terms of ability to answer the clinical question as well as strength of conclusions. A total of 45 articles were found and critiqued, 28 of which were relevant to the clinical question. Evidence strength ranged from level 1 to level 5. Results from the studies were synthesized to create clinical recommendations to guide treatment. Based on best available evidence, it is recommended that pressure therapy is utilized to decrease scar height and erythema that it is used for grafts and wounds requiring 14 to 21 days to heal, for 23 hours/day for 12 months, fit to achieve 20 to 30 mm Hg of

  19. Development of a Best Evidence Statement for the Use of Pressure Therapy for Management of Hypertrophic Scarring.

    Science.gov (United States)

    Sharp, Patricia A; Pan, Brian; Yakuboff, Kevin P; Rothchild, Dawn

    2016-01-01

    Pressure therapy has been considered standard, first-line intervention for the treatment of hypertrophic scars since its introduction in the 1960s. Although widely used, this scar management technique has historically been based on a wide array of anecdotal evidence as opposed to strong scientific support. Evidence has become more prevalent in recent years, necessitating a synthesis to develop an evidence-based clinical guideline. The clinical question was asked, "Among individuals with or at risk to develop active hypertrophic scars, does treatment with pressure therapy improve aesthetic and functional outcomes?" An evidence-based practice project was completed with aims to synthesize relevant literature to determine recommendations for the use of pressure therapy in individuals at risk for hypertrophic scars. A systematic search of the literature was conducted for the dates January 1950 to February 2014 of the following databases: MEDLINE, CINAHL, Cochrane Database for Systematic Reviews, Burntherapist.com, Cochrane Libraries, Ebsco, Google Scholar, OT Seeker, Ovid, MedLine, PEDro.org, Pubmed.gov, Pubmed Clinical Queries, and hand search of relevant articles through use of reference lists. Search terms included scar, hypertroph*, pressure therapy, compression therapy, pressure garment, burn, scald, trauma as well as MeSH terms cicatrix and hypertrophic. Articles were reviewed in terms of ability to answer the clinical question as well as strength of conclusions. A total of 45 articles were found and critiqued, 28 of which were relevant to the clinical question. Evidence strength ranged from level 1 to level 5. Results from the studies were synthesized to create clinical recommendations to guide treatment. Based on best available evidence, it is recommended that pressure therapy is utilized to decrease scar height and erythema that it is used for grafts and wounds requiring 14 to 21 days to heal, for 23 hours/day for 12 months, fit to achieve 20 to 30 mm Hg of

  20. 犬咬伤的急诊处理与美容修复%Emergency treatment and cosmetic repair of bite wound by dog

    Institute of Scientific and Technical Information of China (English)

    刘毅; 刘萍; 宋玫; 肖斌; 陈黎明; 姜疆; 徐承新; 孙晓晨

    2012-01-01

    Objective To summarize the experience of emergency treatment and cosmetic repair of bite wound by dog. Methods The curative effects of 119 wounds from 51 cases of bite wound by dog, to be treated from January 2010 to August 2012, were analyzed retrospectively. The principles of medical aesthetics and plastic and cosmetic surgery were followed. A wound without skin and soft tissue defect was sutured accurately according to tissue zonation with a new suture technique, and the needle distance or side distance was limited in 0.2cm to 0.3cm. Otherwise, the wound was repaired by full-thickness skin graft or various flaps according to the principle of "rather near than further, rather simple than complicated". Delayed repair was emphasized. It was pay attention to rehabilitation care. Results After debridement, 37 wounds were sutured directly, 23 wounds were repaired by full-thickness skin grafting and 29 wounds by various flaps. 111wounds healed on the first stage, and the healing rate reached 93.3%. The wounds were in satisfactory apposition and without obvious cicatrix. Any organs didn't appear in malposition and deformity. Eight wounds which were repaired on the first stage didn't heal, and they were repaired by changing dressings or second operations. 84 wounds from 37 cases were followed up. The results showed good appearance and slight cicatrix hyperplasia, a pigmentation in different degree appeared in five wounds covered by skin grafting. In addition, partial excalation of eyebrow or auricle appeared in 3 cases, and facial neuralgia in one case. Conclusion During treating emergency cases of bite wound by dog, if an idea " cosmetic repair of trauma" is followed, the theory of aesthetics and the techniques of plastic and cosmetic surgery are fully used, and a prompt and accurate treatment is put into practice, the aim of cosmetic repair could be come true. In addition, with those wounds, which couldn't be repaired on the first stage, delayed repair would be

  1. 面部创伤的急诊处理与美容修复%Emergency treatment and cosmetic repair of facial trauma

    Institute of Scientific and Technical Information of China (English)

    刘毅; 刘萍; 宋玫; 肖斌; 张鲜英; 陈黎明; 张绪生; 张诚

    2012-01-01

    Objective To summarize the experience of emergency treatment and cosmetic repair of facial trauma.Methods The clinical materials of 584 wounds from 291 cases of facial trauma,recruited in hospital from January 2010 to August 2012,were summed up retrospectively.The principles of medical aesthetics and plastic and cosmetic surgery were followed.A high pressure douching technique was employed to carry out thorough debridement,but occasion of the debridement did not emphasize with intensive attention.A wound without skin and soft tissue defect was sutured accurately according to tissue zonation with a new suture technique,and the needle distance or side distance was limited in 0.2 cm to 0.3 cm.Otherwise,the wound was repaired by full-thickness skin graft or various flaps according to the repair principle of " rather near than further,rather simple than complicated".Attention was paid to rehabilitation care.Results After debridement,328 wounds were sutured directly,147 wounds were repaired by full-thickness skin grafting and 109 wounds by various flaps.A total of 571 wounds healed on the first stage,and the healing rate reached 97.8%.The wounds were in satisfactory apposition and without obvious cicatrix.Five senses did not appear in malposition and deformity.The other 13 wounds did not heal because of bad taking of skin grafts and flaps or wound splitting.Among them,4 wounds were repaired by second operation,and 9 wounds healed by changing dressings.By means of rehabilitation care,scar hyperplasia and pigmentation appeared slightly in those 13 wounds.A total of 454 wounds from 217 cases were followed up.The results showed good appearance and slight cicatrix hyperplasia,a pigmentation in different degree appeared in 11 wounds covered by skin grafting.In addition,eyebrow excalation,auricle excalation or total lose appeared in 12 cases.Conclusion During treating emergency cases of facial injuries,if an idea "cosmetic repair of trauma"is followed,the theory of aesthetics

  2. 瘢痕疙瘩下埋置扩张器治疗胸前瘢痕疙瘩的临床应用%The Therapy for Chest Keloid Based on Skin Soft Tissue Expansion under Keloid

    Institute of Scientific and Technical Information of China (English)

    高雁; 郑惊雷; 刘玉生; 牛占国; 刘小容; 陈可琼; 黄伟龙

    2015-01-01

    Objective:To study the therapy effect on chest keloid based on skin soft tissue expansion under keloid. Method:29 chest keloid patients were randomly divided into two groups, the skin expander was buried under the keloid in group A, while under the normal skin around the keloid in group B.Then both of the groups received regular water injection treatment to expansion.After reoperation to remove the dilator and to resect the keloid, radiotherapy continued for 5 days.The total length of the operation scar was measured, and the cases of complication and recurrence followed up for 6 months -2 years were counted, and the difference between the both groups was compared.Result:The total length of operation scar was (7.68±1.30)cm in group A while the length was (10.25±2.05)cm in group B, which had significant difference (P0.05). Conclusion:Tissue expansion under the cicatrix has the advantages of safer,less trauma and less operation scar for chest keloid.%目的:探讨在瘢痕疙瘩下埋置扩张器治疗胸前瘢痕疙瘩的临床效果。方法:将29例胸前瘢痕疙瘩患者随机分成两组:A组于瘢痕疙瘩下方埋置皮肤扩张器,B组于瘢痕疙瘩旁埋置皮肤扩张器,两组定期扩张注水治疗,二期手术取出扩张器切除瘢痕,配合电子线连续照射5 d,分别测量二期手术后瘢痕的总长度,随访6个月~2年,统计并发症例数及复发病例数,比较两组差异。结果:A组患者术后瘢痕总长度(7.68±1.30)cm,B组患者术后瘢痕长度(10.25±2.05)cm,两组比较差异有统计学意义(P0.05)。结论:在瘢痕疙瘩下埋置扩张器治疗对于中小面积胸前瘢痕疙瘩是较好的手术方法,提高手术效果。

  3. The experimental study of anti-inflammatory cytokine TSG-6 inhibits hypertrophic scar formation in rabbit ears model%抗炎因子TSG-6抑制兔耳瘢痕增生的实验研究

    Institute of Scientific and Technical Information of China (English)

    王晖; 李小静; 陈钊

    2015-01-01

    Objective To observe the effect of tumor necrosis factorαstimulated gene-6 ( TSG-6 ) on hypertrophic scarring by using a rabbit ear model. Methods TSG-6 and PBS were injected intradermally in the right and left ear wounds, respectively. Collagen I and III expression detected by immunohistochemistry and scar elevation index ( SEI) was used to evaluate the extent of scarring. The expression of inflammatory factors interleukin-1β( IL-1β) , interleukin-6 ( IL-6 ) and tumor necrosis factor-α( TNF-α) was detected by immunohistochemistry and reverse tran-scription polymerase chain reaction. Transmission electron microscope ( TEM) and TUNEL analyses were used to detect fibroblast apoptosis. Results Compared with control scars, TSG-6-treated wounds exhibited decreased in-flammation significantly as evidenced by the lower levels of IL-1β, IL-6 , TNF-α. The apoptosis rate was higher and the SEI and the synthesis of collagens I and III were significantly decreased in the TSG-6-treated scars ( P<0. 05 ) . Conclusion Immediate topical injection of TSG-6 during the wound healing process can reduce the severity of hy-pertrophic scarring in a rabbit model. The anti-cicatrix effect of TSG-6 may result from controlling inflammation, in-ducing fibroblast apoptosis and promoting collagen degradation.%目的:通过建立兔耳增生性瘢痕模型,研究肿瘤坏死因子α刺激基因-6( TSG-6)在增生性瘢痕形成过程中的作用及机制。方法建立兔耳增生性瘢痕模型,右侧耳创面为实验组,注射TSG-6,左侧均注射等量PBS作为对照组,通过比较各组瘢痕指数( SEI)及Ⅰ、Ⅲ型胶原表达的不同来评价瘢痕增生程度的差异。采用免疫组化法及逆转录聚合酶链反应( RT-PCR)法检测炎症因子白细胞介素-1β( IL-1β)、白细胞介素-6(IL-6)及肿瘤坏死因子-α(TNF-α)在各组中的表达;以透射电镜观察及TUNEL法检测瘢痕组织成纤维细胞凋亡的变化。结果与PBS对照组比较,TSG-6

  4. Expression and significance of P57kip2 and Maspin in pathological scar%P57kip2和Maspin在病理性瘢痕组织中的表达

    Institute of Scientific and Technical Information of China (English)

    蔡玉梅; 朱世泽; 郑志芳; 杨维群; 吴文艺

    2011-01-01

    Objective To study the expression of P57kip2 and Maspin in the pathological scar and their possible role in the pathogenesis of abnormal scars.Methods Immunohistochemistry integrated image analysis and reverse transcriptionpolymerase chain reaction (RT-RCR) were performed to detect the expression of P57kip2 and Maspin in hypertrophic scar,keloid,mature scar and normal skin.Statistics was used to analyze the datas.Results The expression of P57kip2 protein was fixed to fibroblast intranuclear in abnormal scar,and the expression of P57kip2 protein and P57kip2 mRNA decreased ( P < 0.05 ).The expression of Maspin protein was fixed to fibroblast cytoplasm and intranuclear in abnormal scar,and the expression of Maspin protein and Maspin mRNA decrease,compared with that in normal group ( P <0.05).There was positive correlation between P57kip2 protein and Maspin protein expression( P < 0.01 ).Conclusions The decreased expression of P57kip2 and Maspin in abnormal scar shows that they are cicatrix-related genes.There is a positive relationship between the two genes.It may be one of the mechanisms of pathogenesis of abnormal scar.It makes effect through fibroblasts.%目的 研究P57kip2和Maspin在病理性瘢痕组织中的表达情况及相互关系,探讨它们在病理性瘢痕形成中的作用及机制.方法 应用免疫组化SP法结合计算机病理图像分析和逆转录聚合酶链反应( RT-PCR)检测正常皮肤、成熟瘢痕、增生性瘢痕和瘢痕疙瘩组织中P57kip2和Maspin的表达并对其表达进行统计学分析.结果 病理性瘢痕组织中P57kip2蛋白的表达定位于成纤维细胞的细胞核内,且P57kip2蛋白及mRNA的表达减少,与正常皮肤、成熟瘢痕对照组比较差异有统计学意义(P<0.05).病理性瘢痕组织中Maspin蛋白的表达定位于成纤维细胞的细胞质和细胞核内,且Maspin蛋白及mRNA的表达减少,与正常皮肤、成熟瘢痕对照组比较差异有统计学意义(P<0.05).P57kip2