Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes.

Science.gov (United States)

Hopkins, Jessica; Hwang, Grace; Jacob, Justin; Sapp, Nicklas; Bedigian, Rick; Oka, Kazuhiro; Overbeek, Paul; Murray, Steve; Jordan, Philip W

2014-07-01

Cohesins are important for chromosome structure and chromosome segregation during mitosis and meiosis. Cohesins are composed of two structural maintenance of chromosomes (SMC1-SMC3) proteins that form a V-shaped heterodimer structure, which is bridged by a α-kleisin protein and a stromal antigen (STAG) protein. Previous studies in mouse have shown that there is one SMC1 protein (SMC1β), two α-kleisins (RAD21L and REC8) and one STAG protein (STAG3) that are meiosis-specific. During meiosis, homologous chromosomes must recombine with one another in the context of a tripartite structure known as the synaptonemal complex (SC). From interaction studies, it has been shown that there are at least four meiosis-specific forms of cohesin, which together with the mitotic cohesin complex, are lateral components of the SC. STAG3 is the only meiosis-specific subunit that is represented within all four meiosis-specific cohesin complexes. In Stag3 mutant germ cells, the protein level of other meiosis-specific cohesin subunits (SMC1β, RAD21L and REC8) is reduced, and their localization to chromosome axes is disrupted. In contrast, the mitotic cohesin complex remains intact and localizes robustly to the meiotic chromosome axes. The instability of meiosis-specific cohesins observed in Stag3 mutants results in aberrant DNA repair processes, and disruption of synapsis between homologous chromosomes. Furthermore, mutation of Stag3 results in perturbation of pericentromeric heterochromatin clustering, and disruption of centromere cohesion between sister chromatids during meiotic prophase. These defects result in early prophase I arrest and apoptosis in both male and female germ cells. The meiotic defects observed in Stag3 mutants are more severe when compared to single mutants for Smc1β, Rec8 and Rad21l, however they are not as severe as the Rec8, Rad21l double mutants. Taken together, our study demonstrates that STAG3 is required for the stability of all meiosis-specific cohesin

Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes.

Directory of Open Access Journals (Sweden)

Jessica Hopkins

2014-07-01

Full Text Available Cohesins are important for chromosome structure and chromosome segregation during mitosis and meiosis. Cohesins are composed of two structural maintenance of chromosomes (SMC1-SMC3 proteins that form a V-shaped heterodimer structure, which is bridged by a α-kleisin protein and a stromal antigen (STAG protein. Previous studies in mouse have shown that there is one SMC1 protein (SMC1β, two α-kleisins (RAD21L and REC8 and one STAG protein (STAG3 that are meiosis-specific. During meiosis, homologous chromosomes must recombine with one another in the context of a tripartite structure known as the synaptonemal complex (SC. From interaction studies, it has been shown that there are at least four meiosis-specific forms of cohesin, which together with the mitotic cohesin complex, are lateral components of the SC. STAG3 is the only meiosis-specific subunit that is represented within all four meiosis-specific cohesin complexes. In Stag3 mutant germ cells, the protein level of other meiosis-specific cohesin subunits (SMC1β, RAD21L and REC8 is reduced, and their localization to chromosome axes is disrupted. In contrast, the mitotic cohesin complex remains intact and localizes robustly to the meiotic chromosome axes. The instability of meiosis-specific cohesins observed in Stag3 mutants results in aberrant DNA repair processes, and disruption of synapsis between homologous chromosomes. Furthermore, mutation of Stag3 results in perturbation of pericentromeric heterochromatin clustering, and disruption of centromere cohesion between sister chromatids during meiotic prophase. These defects result in early prophase I arrest and apoptosis in both male and female germ cells. The meiotic defects observed in Stag3 mutants are more severe when compared to single mutants for Smc1β, Rec8 and Rad21l, however they are not as severe as the Rec8, Rad21l double mutants. Taken together, our study demonstrates that STAG3 is required for the stability of all meiosis

Sister chromatid segregation in meiosis II

Science.gov (United States)

Wassmann, Katja

2013-01-01

Meiotic divisions (meiosis I and II) are specialized cell divisions to generate haploid gametes. The first meiotic division with the separation of chromosomes is named reductional division. The second division, which takes place immediately after meiosis I without intervening S-phase, is equational, with the separation of sister chromatids, similar to mitosis. This meiotic segregation pattern requires the two-step removal of the cohesin complex holding sister chromatids together: cohesin is removed from chromosome arms that have been subjected to homologous recombination in meiosis I and from the centromere region in meiosis II. Cohesin in the centromere region is protected from removal in meiosis I, but this protection has to be removed—deprotected”—for sister chromatid segregation in meiosis II. Whereas the mechanisms of cohesin protection are quite well understood, the mechanisms of deprotection have been largely unknown until recently. In this review I summarize our current knowledge on cohesin deprotection. PMID:23574717

X-ray sensitization of chromatids with unifilarly and bifilarly substituted DNA

International Nuclear Information System (INIS)

Wolff, S.

1981-01-01

When cells are grown for two rounds of DNA replication in the presence of the thymidine analogue 5-bromodeoxyuridine, chromosomes containing one chromatid with unifilarly substituted DNA and one with bifilarly substituted DNA are found. These can be distinguished by harlequin staining techniques that stain one chromatid dark and one light. When the degree of substitution is 60% or greater, 3 times as many X-ray-induced chromatid breaks are produced as in unsubstituted chromatids. This represents maximal sensitization. The unifilarly substituted (dark) chromatid is as sensitive as its bifilarly substituted (light) sister chromatid. If cells are grown in low concentrations of 5-bromodeoxyuridine (BrdUrd), then the amount of substitution is less and the bifilarly substituted chromatic is more sensitive than the unifilarly substituted one. When large numbers of cells are grown in very low concentrations of BrdUrd, the analogue is almost completely depleted during the first round of replication leading to harlequin chromosomes containing one unsubstituted (dark) and one unifilarly substituted (light) chromatid. Under these conditions a maximal sensitization between light-staining and dark-staining chromatids can occur. This can be confused with the differential sensitivity between unifilarly and bifilarly substituted chromatids. The apparent discrepant results obtained by different investigators are most likely caused by the use of very low levels of BrdUrd in some of the experiments. (orig.)

Modelling and testing the molecular mechanism of radiation-induced chromatid breaks

International Nuclear Information System (INIS)

Bryant, P. E.

2001-01-01

Chromatid breaks induced by ionizing radiation in the G2 phase of the cell cycle are considered as markers of individual human radiosensitivity and may indicate the presence of low-penetrance genes regulating susceptibility to breast and other cancers). Together with our own study of Scottish (Tayside) breast cancer patients and a group of normal controls these studies show an overall 10-fold variation in chromatid break frequency (the parameter defining individual chromosomal 'radiosensitivity'). Thus, an understanding of the mechanisms and genes involved in determining these widely different responses should help to clarify the reasons for individual radiosensitivity and may lead us to identify key genes involved in cancer susceptibility. The presence of colour-switches at around 16% of chromatid break points (detected in harlequin-stained chromosomes) indicates that this type of chromatid break is formed by a chromatin rearrangement involving one or more large chromatin domains of the order of 3 - 5 Mbp, possibly representing transcription 'factories'. The signal model of chromatid breaks assumes that all chromatid breaks are the result of chromatin rearrangements, and that the initiating DNA double-strand break (dsb) is itself not involved in the rearrangement but signals its presence (possibly via ATM protein or DNAPK) leading to the initiation of the chromatin rearrangement. Experimental evidence from radiosensitive cell lines (e.g. human AT and hamster irs2) and with the nucleoside analogue araA (9-β-D-arabinofuranosyladenine) demonstrates the lack of correspondence between the rejoining kinetics of dsb and that of disappearance of chromatid breaks, thus supporting the signal model. Coupled with the linear induction of chromatid breaks with dose in both human and rodent cell lines of various types, and the production of chromatid breaks by single dsb in genetically engineered cell lines the classical 'breakage-first' model of chromatid breaks is no longer

G2-chromatid breaks and rejoining in HO8910 cells induced by γ-rays

International Nuclear Information System (INIS)

Wang Zhuanzi; Liu Bing; Duan Xin

2006-01-01

The premature chromosome condensation technique was used to estimate the dosage effect on the G2-chromosome breaks in HO8910 after exposure to γ-rays, and to investigate the time effect on the rejoining of the G2-chromosome breaks. The results show that the number of G2 chromatid-type breaks linearly increased with doses and the number of G2 iso-chromatid breaks increased with dose in a linear-square manner. With the prolongation of culture time, G2 chromatid-type breaks obviously got repaired, and almost 65% chromatid-type breaks got repaired in the early 24 hour post-irradiation, whereas only about 20% iso-chromatid breaks got repaired during the same time. Furthermore, the rejoining of the two types of chromatid breaks occurred mostly in 2 hours after irradiation and from 12 to 24 hours after irradiation, the number of chromatid breaks was found to get stabilized basically, which indicates that the repairing process is over in the early 24 hours of post-irradiation. (authors)

Epigenetic differences between sister chromatids?

NARCIS (Netherlands)

Lansdorp, Peter M.; Falconer, Ester; Tao, Jiang; Brind'Amour, Julie; Naumann, Ulrike; Kanz, L; Fibbe, WE; Lengerke, C; Dick, JE

2012-01-01

Semi-conservative replication ensures that the DNA sequence of sister chromatids is identical except for replication errors and variation in the length of telomere repeats resulting from replicative losses and variable end processing. What happens with the various epigenetic marks during DNA

Phospho-H1 Decorates the Inter-chromatid Axis and Is Evicted along with Shugoshin by SET during Mitosis.

Science.gov (United States)

Krishnan, Swathi; Smits, Arne H; Vermeulen, Michiel; Reinberg, Danny

2017-08-17

Precise control of sister chromatid separation during mitosis is pivotal to maintaining genomic integrity. Yet, the regulatory mechanisms involved are not well understood. Remarkably, we discovered that linker histone H1 phosphorylated at S/T18 decorated the inter-chromatid axial DNA on mitotic chromosomes. Sister chromatid resolution during mitosis required the eviction of such H1S/T18ph by the chaperone SET, with this process being independent of and most likely downstream of arm-cohesin dissociation. SET also directed the disassembly of Shugoshins in a polo-like kinase 1-augmented manner, aiding centromere resolution. SET ablation compromised mitotic fidelity as evidenced by unresolved sister chromatids with marked accumulation of H1S/T18ph and centromeric Shugoshin. Thus, chaperone-assisted eviction of linker histones and Shugoshins is a fundamental step in mammalian mitotic progression. Our findings also elucidate the functional implications of the decades-old observation of mitotic linker histone phosphorylation, serving as a paradigm to explore the role of linker histones in bio-signaling processes. Copyright © 2017 Elsevier Inc. All rights reserved.

Towards a Cohesive Theory of Cohesion

Directory of Open Access Journals (Sweden)

Janet McLeod

2013-12-01

Full Text Available Conventional wisdom suggests that group cohesion is strongly related to performance. This may be based on the notion that better cohesion leads to the sharing of group goals. However, empirical and meta-analytic studies have been unable to consistently demonstrate a relationship between cohesion and performance. Partially, this problem could be attributed to the disagreement on the precise definition of cohesion and its components. Further, when the cohesion construct is evaluated under Cohen’s Cumulative Research Program (CRP, it is surprisingly found to belong to the category of early-to-intermediate stage of theory development. Therefore, a thorough re-examination of the cohesion construct is essential to advance our understanding of the cohesion-productivity relationship. We propose a qualitative approach because it will help establish the definitions, enable us to better test our theories about cohesion and its moderators, and provide insights into how best to enlist cohesion to improve team performance.

Chl1 DNA helicase regulates Scc2 deposition specifically during DNA-replication in Saccharomyces cerevisiae.

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Soumya Rudra

Full Text Available The conserved family of cohesin proteins that mediate sister chromatid cohesion requires Scc2, Scc4 for chromatin-association and Eco1/Ctf7 for conversion to a tethering competent state. A popular model, based on the notion that cohesins form huge ring-like structures, is that Scc2, Scc4 function is essential only during G1 such that sister chromatid cohesion results simply from DNA replisome passage through pre-loaded cohesin rings. In such a scenario, cohesin deposition during G1 is temporally uncoupled from Eco1-dependent establishment reactions that occur during S-phase. Chl1 DNA helicase (homolog of human ChlR1/DDX11 and BACH1/BRIP1/FANCJ helicases implicated in Fanconi anemia, breast and ovarian cancer and Warsaw Breakage Syndrome plays a critical role in sister chromatid cohesion, however, the mechanism through which Chl1 promotes cohesion remains poorly understood. Here, we report that Chl1 promotes Scc2 loading unto DNA such that both Scc2 and cohesin enrichment to chromatin are defective in chl1 mutant cells. The results further show that both Chl1 expression and chromatin-recruitment are tightly regulated through the cell cycle, peaking during S-phase. Importantly, kinetic ChIP studies reveals that Chl1 is required for Scc2 chromatin-association specifically during S-phase, but not during G1. Despite normal chromatin enrichment of both Scc2 and cohesin during G1, chl1 mutant cells exhibit severe chromosome segregation and cohesion defects--revealing that G1-loaded cohesins is insufficient to promote cohesion. Based on these findings, we propose a new model wherein S-phase cohesin loading occurs during DNA replication and in concert with both cohesion establishment and chromatin assembly reactions--challenging the notion that DNA replication fork navigates through or around pre-loaded cohesin rings.

Cell elongation is an adaptive response for clearing long chromatid arms from the cleavage plane

Science.gov (United States)

Kotadia, Shaila; Montembault, Emilie; Sullivan, William

2012-01-01

Chromosome segregation must be coordinated with cell cleavage to ensure correct transmission of the genome to daughter cells. Here we identify a novel mechanism by which Drosophila melanogaster neuronal stem cells coordinate sister chromatid segregation with cleavage furrow ingression. Cells adapted to a dramatic increase in chromatid arm length by transiently elongating during anaphase/telophase. The degree of cell elongation correlated with the length of the trailing chromatid arms and was concomitant with a slight increase in spindle length and an enlargement of the zone of cortical myosin distribution. Rho guanine-nucleotide exchange factor (Pebble)–depleted cells failed to elongate during segregation of long chromatids. As a result, Pebble-depleted adult flies exhibited morphological defects likely caused by cell death during development. These studies reveal a novel pathway linking trailing chromatid arms and cortical myosin that ensures the clearance of chromatids from the cleavage plane at the appropriate time during cytokinesis, thus preserving genome integrity. PMID:23185030

Regulation of the Drosophila Enhancer of split and invected-engrailed gene complexes by sister chromatid cohesion proteins.

Directory of Open Access Journals (Sweden)

Cheri A Schaaf

2009-07-01

Full Text Available The cohesin protein complex was first recognized for holding sister chromatids together and ensuring proper chromosome segregation. Cohesin also regulates gene expression, but the mechanisms are unknown. Cohesin associates preferentially with active genes, and is generally absent from regions in which histone H3 is methylated by the Enhancer of zeste [E(z] Polycomb group silencing protein. Here we show that transcription is hypersensitive to cohesin levels in two exceptional cases where cohesin and the E(z-mediated histone methylation simultaneously coat the entire Enhancer of split and invected-engrailed gene complexes in cells derived from Drosophila central nervous system. These gene complexes are modestly transcribed, and produce seven of the twelve transcripts that increase the most with cohesin knockdown genome-wide. Cohesin mutations alter eye development in the same manner as increased Enhancer of split activity, suggesting that similar regulation occurs in vivo. We propose that cohesin helps restrain transcription of these gene complexes, and that deregulation of similarly cohesin-hypersensitive genes may underlie developmental deficits in Cornelia de Lange syndrome.

Psychological characteristics of group cohesion athletes.

OpenAIRE

Sheriff Sarhan

2011-01-01

The basic components of group cohesion in sport teams. An analysis of publications on cohesion within the groups where an interconnection of individual goals of each participant group with common goals and the end result of teamwork. The concept of harmony in the team sports, where the rate of group cohesion is dependent on such integrative index as psychological climate. It is established that a number of athletes to achieve high results require high cohesion, unity, value-normative orientat...

Psychological characteristics of group cohesion athletes.

Directory of Open Access Journals (Sweden)

Sheriff Sarhan

2011-07-01

Full Text Available The basic components of group cohesion in sport teams. An analysis of publications on cohesion within the groups where an interconnection of individual goals of each participant group with common goals and the end result of teamwork. The concept of harmony in the team sports, where the rate of group cohesion is dependent on such integrative index as psychological climate. It is established that a number of athletes to achieve high results require high cohesion, unity, value-normative orientation, deep identification and responsibility for the results of the joint group activities.

Effect of chloramphenicol on sister chromatid exchange in bovine fibroblasts.

Science.gov (United States)

Arruga, M V; Catalan, J; Moreno, C

1992-03-01

The genotoxic potential of different chloramphenicol concentrations (5, 20, 40 and 60 micrograms ml-1) was investigated in bovine fibroblast primary lines by sister chromatid exchange assay. Chloramphenicol acted for long enough to ensure similar effects to persistent storage in the kidney. In this experiment 10 micrograms ml-1 of 5-bromodeoxyuridine was added for 60 hours for all doses of chloramphenicol and to the control. When the tissue culture cells were exposed to increasing doses, increased numbers of sister chromatid exchanges developed. Differences were significantly different to the control.

Similar kinetics of chromatid aberrations in X-irradiated xrs 5 and wild-type Chinese hamster ovary cells

International Nuclear Information System (INIS)

MacLeod, R.A.F.; Bryant, P.E.

1990-01-01

We have studied the kinetics of chromatid aberrations in cells of the Chinese hamster ovary (CHO-K1) derived, X-ray sensitive cell line xrs 5 irradiated in the G 2 phase at 37 0 C, as well as during a cell cycle extended by transient hypothermia at 33 0 C. While a given X-ray dose was estimated to produce about 4 times as many chromatid break and twice the frequency of exchanges in xrs 5 cells as in the parent line, there was no difference between the lines in the rates of disappearance of chromatid breaks during G 2 at either temperature; and similar patterns of chromatid exchange kinetics were observed in the two lines. Both the frequencies and distributions of chromatid breaks at different times after irradiation are consistent with the view that the disappearance of these during incubation represents a repair process. These results imply that the G 2 chromosomal radiosensitivity of the xrs 5 mutant resides at the level of initial chromatid damage. (author)

Network cohesion

OpenAIRE

Cavalcanti, Tiago Vanderlei; Giannitsarou, Chrysi; Johnson, CR

2017-01-01

We define a measure of network cohesion and show how it arises naturally in a broad class of dynamic models of endogenous perpetual growth with network externalities. Via a standard growth model, we show why network cohesion is crucial for conditional convergence and explain that as cohesion increases, convergence is faster. We prove properties of network cohesion and define a network aggregator that preserves network cohesion.

Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq

NARCIS (Netherlands)

Claussin, Clemence; Porubsky, David; Spierings, Diana C. J.; Halsema, Nancy; Rentas, Stefan; Guryev, Victor; Lansdorp, Peter M.; Chang, Michael

2017-01-01

Homologous recombination involving sister chromatids is the most accurate, and thus most frequently used, form of recombination-mediated DNA repair. Despite its importance, sister chromatid recombination is not easily studied because it does not result in a change in DNA sequence, making

Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes.

Science.gov (United States)

Pongsavee, Malinee

2009-10-30

Borax is used as a food additive. It becomes toxic when accumulated in the body. It causes vomiting, fatigue and renal failure. The heparinized blood samples from 40 healthy men were studied for the impact of borax toxicity on immune cell proliferation (lymphocyte proliferation) and sister chromatid exchange in human chromosomes. The MTT assay and Sister Chromatid Exchange (SCE) technic were used in this experiment with the borax concentrations of 0.1, 0.15, 0.2, 0.3 and 0.6 mg/ml. It showed that the immune cell proliferation (lymphocyte proliferation) was decreased when the concentrations of borax increased. The borax concentration of 0.6 mg/ml had the most effectiveness to the lymphocyte proliferation and had the highest cytotoxicity index (CI). The borax concentrations of 0.15, 0.2, 0.3 and 0.6 mg/ml significantly induced sister chromatid exchange in human chromosomes (P Borax had effects on immune cell proliferation (lymphocyte proliferation) and induced sister chromatid exchange in human chromosomes. Toxicity of borax may lead to cellular toxicity and genetic defect in human.

A comparison of G2 phase radiation-induced chromatid break kinetics using calyculin-PCC with those obtained using colcemid block.

Science.gov (United States)

Bryant, Peter E; Mozdarani, Hossein

2007-09-01

To study the possible influence of cell-cycle delay on cells reaching mitosis during conventional radiation-induced chromatid break experiments using colcemid as a blocking agent, we have compared the chromatid break kinetics following a single dose of gamma rays (0.75 Gy) in metaphase CHO cells using calyculin-induced premature chromosome condensation (PCC), with those using colcemid block. Calyculin-induced PCC causes very rapid condensation of G2 cell chromosomes without the need for a cell to progress to mitosis, hence eliminating any effect of cell-cycle checkpoint on chromatid break frequency. We found that the kinetics of the exponential first-order decrease in chromatid breaks with time after irradiation was similar (not significantly different) between the two methods of chromosome condensation. However, use of the calyculin-PCC technique resulted in a slightly increased rate of disappearance of chromatid breaks and thus higher frequencies of breaks at 1.5 and 2.5 h following irradiation. We also report on the effect of the nucleoside analogue ara A on chromatid break kinetics using the two chromosome condensation techniques. Ara A treatment of cells abrogated the decrease in chromatid breaks with time, both using the calyculin-PCC and colcemid methods. We conclude that cell-cycle delay may be a factor determining the absolute frequency of chromatid breaks at various times following irradiation of cells in G2 phase but that the first-order disappearance of chromatid breaks with time and its abrogation by ara A are not significantly influenced by the G2 checkpoint.

Immigration, social cohesion, and naturalization

DEFF Research Database (Denmark)

Lægaard, Sune

2010-01-01

social trust do not connect with issues of naturalization at all. Other conceptions of social cohesion are either politically controversial, problematic as part of the justification of stricter naturalization requirements, or in fact justify less demanding naturalization requirements....

Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes

Directory of Open Access Journals (Sweden)

Pongsavee Malinee

2009-10-01

Full Text Available Abstract Background Borax is used as a food additive. It becomes toxic when accumulated in the body. It causes vomiting, fatigue and renal failure. Methods The heparinized blood samples from 40 healthy men were studied for the impact of borax toxicity on immune cell proliferation (lymphocyte proliferation and sister chromatid exchange in human chromosomes. The MTT assay and Sister Chromatid Exchange (SCE technic were used in this experiment with the borax concentrations of 0.1, 0.15, 0.2, 0.3 and 0.6 mg/ml. Results It showed that the immune cell proliferation (lymphocyte proliferation was decreased when the concentrations of borax increased. The borax concentration of 0.6 mg/ml had the most effectiveness to the lymphocyte proliferation and had the highest cytotoxicity index (CI. The borax concentrations of 0.15, 0.2, 0.3 and 0.6 mg/ml significantly induced sister chromatid exchange in human chromosomes (P Conclusion Borax had effects on immune cell proliferation (lymphocyte proliferation and induced sister chromatid exchange in human chromosomes. Toxicity of borax may lead to cellular toxicity and genetic defect in human.

Network cohesion

OpenAIRE

Cavalcanti, Tiago V. V.; Giannitsarou, Chryssi; Johnson, Charles R.

2016-01-01

This is the final version of the article. It first appeared from Springer via http://dx.doi.org/10.1007/s00199-016-0992-1 We define a measure of network cohesion and show how it arises naturally in a broad class of dynamic models of endogenous perpetual growth with network externalities. Via a standard growth model, we show why network cohesion is crucial for conditional convergence and explain that as cohesion increases, convergence is faster. We prove properties of network cohesion and d...

Investigations into the molecular mechanism of chromatid breakage in the G2-phase of mammalian cells

International Nuclear Information System (INIS)

Bryant, P.E.; Armstrong, G.N.; Gray, L.; Frankenberg, D.; Mozdarani, H.

2003-01-01

Chromatid breakage following irradiation of cells in the G2-phase of the cell cycle results from the induction of DNA double-strand breaks (dsb). The conversion of dsb into chromatid breaks (cb) has a genetic basis, seemingly different from that of dsb rejoining. The variation in extent of this conversion is exemplified by the stiking variation in frequency of cb in irradiated cycling T-lymphocytes between different normal individuals. Elevated cb frequency in lymphocytes of around 40% of breast cancer patients and their first-degree relatives suggests the presence of mutations in low penetrance cancer predisposing genes that also affect conversion of dsb to cb. Investigation of the mechanism of chromatid radiosensitivity using genetically engineered rodent cell lines containing unique dsb break sites indicate that a single isolated dsb is sufficient to cause a cb. The single-event nature of chromatid breakage is confirmed by the fact that cb are induced as a linear function of radiation dose. Moreover, we have recently shown that ultrasoft carbon-K X-rays also induce chromatid breakage. In this case the energy of the secondary electrons produced by carbon-K X-rays is too low to span more than one DNA double helix, thus further supporting our conclusion that a single dsb is responsible for the formation of a cb. Chromatid breakage is thought to involve a rearrangement between DNA strands at the crossover points of chromatin loop(s) triggered by the presence of a dsb within the loop structure. The occasional observation of 'looped-out' sections of chromatin at cb sites supports this hypothesis. The occurrence of 'colour-switches' between FPG stained chromatids at a proportion of break sites (e.g. about 16% in CHO cells) shows that a significant proportion of cb definitely result from chromatin rearrangements. Measurements of altered colour-switch ratio (csr) in mutant rodent and human cells (irs1 and AT cells respectively) also indicate a genetic basis for the

Relating Cohesive Zone Model to Linear Elastic Fracture Mechanics

Science.gov (United States)

Wang, John T.

2010-01-01

The conditions required for a cohesive zone model (CZM) to predict a failure load of a cracked structure similar to that obtained by a linear elastic fracture mechanics (LEFM) analysis are investigated in this paper. This study clarifies why many different phenomenological cohesive laws can produce similar fracture predictions. Analytical results for five cohesive zone models are obtained, using five different cohesive laws that have the same cohesive work rate (CWR-area under the traction-separation curve) but different maximum tractions. The effect of the maximum traction on the predicted cohesive zone length and the remote applied load at fracture is presented. Similar to the small scale yielding condition for an LEFM analysis to be valid. the cohesive zone length also needs to be much smaller than the crack length. This is a necessary condition for a CZM to obtain a fracture prediction equivalent to an LEFM result.

A schedule to demonstrate radiation-induced sister chromatid exchanges in human lymphocytes

International Nuclear Information System (INIS)

Chaudhuri, J.P.

1982-01-01

The reciprocal interchange between the chromatids of a chromosome, termed sister chromatid exchange (SCE), is considered to be one of the most sensitive and accurate cytogenetic parameters and respond to toxic chemicals at very low doses. But the response of SCE to ionizing radiation is very poor. Human lymphocytes fail to give SCE response when irradiated at G 0 . Probably the primary lesions induced at G 0 do not remain available long enough to find expression as SCEs. Based on this assumption a schedule was developed using caffeine to demonstrate radiation induced SCEs. Following this schedule a dose-dependent increase in the frequency of radiation induced SCEs has been observed. (orig.)

Sister chromatid exchange in peripheral blood lymphocytes as a ...

African Journals Online (AJOL)

Introduction: Sister chromatid exchanges (SCEs) can be induced by various genotoxic treatments, suggesting that SCEs refl ect a DNA repair process and it may be a good index for assessment of genomic instability. However, the occurrence of genetic instability and in particular, of spontaneous SCEs has been strongly ...

Investigating Some Technical Issues on Cohesive Zone Modeling of Fracture

Science.gov (United States)

Wang, John T.

2011-01-01

This study investigates some technical issues related to the use of cohesive zone models (CZMs) in modeling fracture processes. These issues include: why cohesive laws of different shapes can produce similar fracture predictions; under what conditions CZM predictions have a high degree of agreement with linear elastic fracture mechanics (LEFM) analysis results; when the shape of cohesive laws becomes important in the fracture predictions; and why the opening profile along the cohesive zone length needs to be accurately predicted. Two cohesive models were used in this study to address these technical issues. They are the linear softening cohesive model and the Dugdale perfectly plastic cohesive model. Each cohesive model constitutes five cohesive laws of different maximum tractions. All cohesive laws have the same cohesive work rate (CWR) which is defined by the area under the traction-separation curve. The effects of the maximum traction on the cohesive zone length and the critical remote applied stress are investigated for both models. For a CZM to predict a fracture load similar to that obtained by an LEFM analysis, the cohesive zone length needs to be much smaller than the crack length, which reflects the small scale yielding condition requirement for LEFM analysis to be valid. For large-scale cohesive zone cases, the predicted critical remote applied stresses depend on the shape of cohesive models used and can significantly deviate from LEFM results. Furthermore, this study also reveals the importance of accurately predicting the cohesive zone profile in determining the critical remote applied load.

Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes

OpenAIRE

Pongsavee Malinee

2009-01-01

Abstract Background Borax is used as a food additive. It becomes toxic when accumulated in the body. It causes vomiting, fatigue and renal failure. Methods The heparinized blood samples from 40 healthy men were studied for the impact of borax toxicity on immune cell proliferation (lymphocyte proliferation) and sister chromatid exchange in human chromosomes. The MTT assay and Sister Chromatid Exchange (SCE) technic were used in this experiment with the borax concentrations of 0.1, 0.15, 0.2, 0...

Post-irradiation treatment of human lymphocytes with spermidine reduced frequency of chromatid breaks

International Nuclear Information System (INIS)

Bocian, E.; Rosiek, O.; Ziemba-Zoltowska, B.

1978-01-01

Human lymphocyte cultures were X-irradiated with a single dose of 100 or 200 rad 46 h after phytohemagglutinin stimulation. In dose-fractionation experiments, 2h later the second dose was applied. All the cultures were harvested at 54 h after their initiation. In lymphocytes irradiated with a single dose of 200 rad, 2h post-irradiation contact with 10 -5 M exogeneous spermidine resulted in reduction of chromatid breaks by 34 %. Introduction of spermidine into culture medium for fractionation interval between the 2 doses of 100 rad reduced the frequency of chromatid breaks by 42 %. (author)

LRRC45 Is a Centrosome Linker Component Required for Centrosome Cohesion

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Runsheng He

2013-09-01

Full Text Available During interphase, centrosomes are connected by a proteinaceous linker between the proximal ends of the centrioles, which is important for the centrosomes to function as a single microtubule-organizing center. However, the composition and regulation of centrosomal linker remain largely unknown. Here, we show that LRRC45 is a centrosome linker that localizes at the proximal ends of the centrioles and forms fiber-like structures between them. Depletion of LRRC45 results in centrosome splitting during interphase. Moreover, LRRC45 interacts with both C-Nap1 and rootletin and is phosphorylated by Nek2A at S661 during mitosis. After phosphorylation, both LRRC45 centrosomal localization and fiber-like structures are significantly reduced, which subsequently leads to centrosome separation. Thus, LRRC45 is a critical component of the proteinaceous linker between two centrioles and is required for centrosome cohesion.

Chromatid interchanges at intrachromosomal telomeric DNA sequences

International Nuclear Information System (INIS)

Fernandez, J.L.; Vazquez-Gundin, F.; Bilbao, A.; Gosalvez, J.; Goyanes, V.

1997-01-01

Chinese hamster Don cells were exposed to X-rays, mitomycin C and teniposide (VM-26) to induce chromatid exchanges (quadriradials and triradials). After fluorescence in situ hybridization (FISH) of telomere sequences it was found that interstitial telomere-like DNA sequence arrays presented around five times more breakage-rearrangements than the genome overall. This high recombinogenic capacity was independent of the clastogen, suggesting that this susceptibility is not related to the initial mechanisms of DNA damage. (author)

Abnormal centromere-chromatid apposition (ACCA) and Peters' anomaly.

Science.gov (United States)

Wertelecki, W; Dev, V G; Superneau, D W

1985-08-01

Abnormal centromere-chromatid apposition (ACCA) was noted in a patient with Peters' anomaly. Previous reports of ACCA emphasized its association with tetraphocomelia and other congenital malformations (Roberts, SC Phocomelia, Pseudothalidomide Syndromes). This report expands the array of congenital malformations associated with ACCA and emphasizes the diagnostic importance of ocular defects for the ascertainment of additional cases of ACCA and its possible relationship with abnormal cell division.

Mechanisms of sister chromatid recombination

International Nuclear Information System (INIS)

Nakai, Sayaka; Machida, Isamu; Tsuji, Satsuki

1985-01-01

Studies using T948 as a model system have been carried out aimed at elucidating the mechanism of sister chromatid recombination (SCR). Characterization of U.V. light- and x-ray-induced SCR, the relationiship between SCR induction and DNA repair using rad mutations, and the relationship between SCR induction and the time of cell division using cdc mutations are presented. It has been supposed that SCR is induced at the phase of S-G 2 following DNA replication, that postreplication break of DNA strands is strongly involved in the induction of SCR, and that induction type of SCR, i.e., conversion type or recombination type, is dependent upon the type of molecular damage of DNA. (Namekawa, K.)

Interchromosomal distribution of gamma ray-induced chromatid aberrations in Chinese hamster ovary cells

International Nuclear Information System (INIS)

Martinez-Lopez, Wilner; Porro, Valentina; Folle, Gustavo A.; Mendez-Acuna, Leticia; Obe, Guenter; Savage, John R.K.

2000-01-01

Inter chromosomal distributions of breakpoints from chromatid-type aberrations induced by gamma rays in Chinese hamster ovary cells were analyzed. In most chromosomes the distribution was as expected from chromosome lengths for simple breaks or the respective relative corrected length in case of exchanges. There were deviations from expectation in a few chromosomes for chromatid breaks, interchanges, intra-arm intra changes and inter-arm intra changes. Especially interesting are the results concerning chromosomes 2 and 8, which were more often involved in exchanges than expected. An 'exchange phenotype' for these chromosomes is proposed and possible explanations for the nonrandom distribution of chromosome breakpoints are presented. (author)

Structure of the Pds5-Scc1 Complex and Implications for Cohesin Function

Directory of Open Access Journals (Sweden)

Kyle W. Muir

2016-03-01

Full Text Available Sister chromatid cohesion is a fundamental prerequisite to faithful genome segregation. Cohesion is precisely regulated by accessory factors that modulate the stability with which the cohesin complex embraces chromosomes. One of these factors, Pds5, engages cohesin through Scc1 and is both a facilitator of cohesion, and, conversely also mediates the release of cohesin from chromatin. We present here the crystal structure of a complex between budding yeast Pds5 and Scc1, thus elucidating the molecular basis of Pds5 function. Pds5 forms an elongated HEAT repeat that binds to Scc1 via a conserved surface patch. We demonstrate that the integrity of the Pds5-Scc1 interface is indispensable for the recruitment of Pds5 to cohesin, and that its abrogation results in loss of sister chromatid cohesion and cell viability.

Sequential loading of cohesin subunits during the first meiotic prophase of grasshoppers.

Directory of Open Access Journals (Sweden)

Ana M Valdeolmillos

2007-02-01

Full Text Available The cohesin complexes play a key role in chromosome segregation during both mitosis and meiosis. They establish sister chromatid cohesion between duplicating DNA molecules during S-phase, but they also have an important role during postreplicative double-strand break repair in mitosis, as well as during recombination between homologous chromosomes in meiosis. An additional function in meiosis is related to the sister kinetochore cohesion, so they can be pulled by microtubules to the same pole at anaphase I. Data about the dynamics of cohesin subunits during meiosis are scarce; therefore, it is of great interest to characterize how the formation of the cohesin complexes is achieved in order to understand the roles of the different subunits within them. We have investigated the spatio-temporal distribution of three different cohesin subunits in prophase I grasshopper spermatocytes. We found that structural maintenance of chromosome protein 3 (SMC3 appears as early as preleptotene, and its localization resembles the location of the unsynapsed axial elements, whereas radiation-sensitive mutant 21 (RAD21 (sister chromatid cohesion protein 1, SCC1 and stromal antigen protein 1 (SA1 (sister chromatid cohesion protein 3, SCC3 are not visualized until zygotene, since they are located in the synapsed regions of the bivalents. During pachytene, the distribution of the three cohesin subunits is very similar and all appear along the trajectories of the lateral elements of the autosomal synaptonemal complexes. However, whereas SMC3 also appears over the single and unsynapsed X chromosome, RAD21 and SA1 do not. We conclude that the loading of SMC3 and the non-SMC subunits, RAD21 and SA1, occurs in different steps throughout prophase I grasshopper meiosis. These results strongly suggest the participation of SMC3 in the initial cohesin axis formation as early as preleptotene, thus contributing to sister chromatid cohesion, with a later association of both RAD21

Possible mechanisms of chromosomal aberrations: VII. Comparative dynamics of sister chromatid disjunction and realization of radiation-induced chromosomal aberrations during mitosis

International Nuclear Information System (INIS)

Lebedeva, L.I.; Akhmamet'eva, E.M.

1994-01-01

An increase in radiation-induced chromosomal aberrations during c-metaphase sister chromatid disjunction was demonstrated in murine bone marrow cells exposed to a total γ-irradiation at 0.5 Gy. Caffeine (Cf) treatment during mitosis partially suppressed the chromatid disjunction rate and increased the number of radiation-induced aberrations in this mitosis. Nalidixic acid (NA) treatment of c-metaphase cells completely suppressed chromatid disjunction and the realization of induced aberrations. Topoisomerase 2 was assumed to be involved during mitosis in both processes

Sister-chromatid exchanges in nuclear fuel workers

International Nuclear Information System (INIS)

Prabhavathi, P. Aruna; Fatima, Shehla K.; Padmavathi, P.; Kumari, C. Kusuma; Reddy, P.P.

1995-01-01

Peripheral blood lymphocyte cultures of 116 smokers and 80 non-smokers who were occupationally exposed to uranyl compounds were analysed for sister-chromatid exchanges (SCEs). Blood samples were collected from 59 non-smokers (control group I) and 47 smokers (control group II) who were not exposed to uranium for control data. A significant increase in SCEs was observed among both smokers and non-smokers exposed to uranyl compounds when compared to their respective controls. In controls, a significant increase in the frequency of SCEs was observed in smokers when compared to non-smokers

The Structure of Group Cohesion.

Science.gov (United States)

Cota, Albert A.; And Others

1995-01-01

Reviews the literature on unidimensional and multidimensional models of cohesion and describes cohesion as a multidimensional construct with primary and secondary dimensions. Found that primary dimensions described the cohesiveness of all or most types of groups, whereas secondary dimensions only described the cohesiveness of specific types of…

Induction and disappearance of G2 chromatid breaks in lymphocytes after low doses of low LET γ - rays and high LET fast neutrons

International Nuclear Information System (INIS)

Vral, Anne; Thierens, Hubert; Baeyens, Ans; De Ridder, Leo

2001-01-01

In view of the potential importance of the G2 assay for detecting chromosomal radiosensitivity and possible predisposition to cancer the need to elucidate the mechanism underlying the formation of chromatid breaks, observed with the G2 assay after low dose irradiation, has been recognised. In this study we irradiated blood samples of 4 healthy donors with low LET γ-rays and high LET neutrons, which initially produce the same number of dsb but of a different quality. By means of the G2 assay, we determined the number of chromatid breaks induced by γ-rays and neutrons and compared the kinetics of chromatid break rejoining for radiations of different quality. In a first set of experiments a dose-response curve for the formation of chromatid breaks was carried out for γ-rays and neutrons with doses ranging between 0.1 and 0.5 Gy. In a second set of experiments the kinetics of chromatid break formation and disappearance was investigated after a dose of 0.5 Gy using post-irradiation times ranging between 0.5 h and 3.5 h. For the highest dose of 0.5 Gy the number of isochromatid breaks were also scored. No significant differences in the number of chromatid breaks were observed between low LET γ-rays and high LET neutrons for the 4 donors at any of the doses given. The dose response curves for the formation of chromatid breaks are linear for both radiation qualities and RBE values equal to one were obtained. Scoring of isochromatid breaks at the highest dose of 0.5 Gy revealed that high LET neutrons are however more effective at inducing isochromatid breaks (RBE of 6.2). The rejoining experiments further showed that the kinetics of disappearance of chromatid breaks following irradiation with low LET γ-rays or high-LET neutrons are not significantly different. T 1/2 0.92 h for γ-rays and t 1/2 = 0.84 h for neutrons were obtained. In conclusion, our results show that at low doses of radiation the induction as well as the disappearance of G2 chromatid breaks is LET

What are sister chromatid exchanges

International Nuclear Information System (INIS)

Evans, H.J.

1977-01-01

The development of new staining techniques to visualise sister chromatid exchange (SCE) in cells exposed to mutagens has led to a better understanding of the mechanisms involved in the formation of such exchanges. SCE are induced by a wide variety of different physical and chemical agents and their incidence provides a sensitive indicator of DNA damage in proliferating mammalian cells. It is shown that lesions which affect one or both strands of the DNA can result in the development of SCE, but only when damaged DNA undergoes replication. The nature of the lesions, the frequency and distribution of SEC in mammalian cells; the sensitivity of the cells to their induction by X-radiation, ultraviolet radiation and chemical mutagens, are discussed and possible mechanisms involved in the formation of SCE during replication considered. (Auth.)

Forms of cohesion in confinement institutions

Directory of Open Access Journals (Sweden)

Ekaterina D. Slobodenyuk

2015-12-01

Full Text Available Objective to identify the diversity of cohesion forms in confinement institutions. Methods qualitative analyses based on indepth semistructured interviews. Results the study included adaptation of Western methodologies of the cohesion phenomenon analysis to the Russian reality and operationalization of the moral bases of group cohesion. This served as the bases for designing a guide for indepth semistructured interviews 10 interviews were conducted with people recently released from general and strict regime colonies. Content analysis of the interviews revealed a number of structural sections that demonstrate the diversity of cohesion forms alongside with one that is most meaningful to the prisoners and therefore the most well perceived and articulated by respondents. Analysis of the latter allowed to identify a set of groups showing different degree and nature of cohesion. By the degree of cohesion one can identify the poorly cohesive groups quotloutsquot moderately cohesive quotredsquot quotthievesquot and highly cohesive quotfightersquot. By the nature of cohesion in the prisonersrsquo community there are both groups united on the basis of social morality quotredsquot quotthievesquot and groups demonstrating a high degree of cohesion based on the social justice morality quotfightersquot. A detailed analysis of the latter group also showed that the cohesion can have both traits of morality social justice and features of social order moral. Scientific novelty using the sociopsychological theory of the moral motives in determining the bases of cohesion. Practical significance the research results can be applied for the development of sociopsychological techniques for the penal system reform.

Cohesion Policy Contributing to Territorial Cohesion – Future Scenarios

Directory of Open Access Journals (Sweden)

Andreas Faludi

2011-09-01

Full Text Available The Barca Report advocates for developmental policies to be ‘place-based’: integrated as far as they affect ‘places’. The debate on territorial cohesion is equally concerned with integrating relevant policies and actions. This requires well-established democratic institutions and adequate responses to the demands of technical systems and of markets. Following Lisbeth Hooghe and Gary Marks, the respective arrangements are described as Governance Type I and Type II. All levels of government, including that of the EU, partake in both types, but relations between them are problematic, particularly in the context of Europe 2020: Will this EU strategy be mainly a matter for Directorate-Generals and their various clients pursuing their policies (Governance Type II, or will Cohesion policy, with its more integrated and decentralised approach, involving many levels of government and stakeholders (Governance Type I form platforms for integrating them? This paper presents four scenarios; each based on a combination of strong/weak Governance Type I and Type II, which are labelled as the ‘Anglo-Saxon’, ‘Saint-Simonian’, ‘Rhineland’ and the ‘European’ Scenarios. The authors prefer the latter, but the best one can hope for in the short term is for this option not to fall by the wayside.

Non-random intrachromosomal distribution of radiation-induced chromatid aberrations in Vicia faba. [Aberration clustering

Energy Technology Data Exchange (ETDEWEB)

Schubert, I; Rieger, R [Akademie der Wissenschaften der DDR, Gatersleben. Zentralinst. fuer Genetik und Kulturpflanzenforschung

1976-04-01

A reconstructed karyotype of Vicia faba, with all chromosomes individually distinguishable, was treated with X-rays, fast neutrons, (/sup 3/H) uridine (/sup 3/HU). The distribution within metaphase chromosomes of induced chromatid aberrations was non-random for all agents used. Aberration clustering, in part agent specific, occurred in chromosome segments containing heterochromatin as defined by the presence of G bands. The pattern of aberration clustering found after treatment with /sup 3/HU did not allow the recognition of chromosome regions active in transcription during treatment. Furthermore, it was impossible to obtain unambiguous indications of the presence of AT- and GC-base clusters from the patterns of /sup 3/HT- and /sup 3/HC-induced chromatid aberrations, respectively. Possible reasons underlying these observations are discussed.

A Study on the Effect of Cohesive Laws on Finite Element Analysis of Crack Propagation Using Cohesive Elements

Energy Technology Data Exchange (ETDEWEB)

Seo, Hyeongseok; Baek, Hyungchan; Kim, Hyungyu [Seoul Nat' l Univ. of Sci. and Tech., Seoul (Korea, Republic of)

2014-04-15

In this paper, the effect of cohesive laws on the finite element analysis of crack propagation using cohesive elements is investigated through three-point bending and double cantilever beam problems. The cohesive elements are implemented into ABAQUS/Standard user subroutines(UEL), and the shape of cohesive law is varied by changing parameters in polynomial functions of cohesive traction-separation relations. In particular, crack propagation behaviors are studied by comparing load-displacement curves of the analysis models which have different shapes of cohesive laws with the same values of fracture energy and cohesive strength. Furthermore, the influence of the element size on crack propagation is discussed in this study.

Design of Normal Concrete Mixtures Using Workability-Dispersion-Cohesion Method

OpenAIRE

Qasrawi, Hisham

2016-01-01

The workability-dispersion-cohesion method is a new proposed method for the design of normal concrete mixes. The method uses special coefficients called workability-dispersion and workability-cohesion factors. These coefficients relate workability to mobility and stability of the concrete mix. The coefficients are obtained from special charts depending on mix requirements and aggregate properties. The method is practical because it covers various types of aggregates that may not be within sta...

Biomonitoring of genotoxic risk in radar facility workers: comparison of the comet assay with micronucleus assay and chromatid breakage assay

International Nuclear Information System (INIS)

Garaj-Vrhovac, V.; Kopjar, N.

2003-01-01

Genotoxic risks of occupational exposure in a radar facility were evaluated by using alkaline comet assay, micronucleus assay and chromatid breakage assay on peripheral blood leukocytes in exposed subjects and corresponding controls. Results show that occupational exposure to microwave radiation correlates with an increase of genome damage in somatic cells. The levels of DNA damage in exposed subjects determined by using alkaline comet assay were increased compared to control and showed interindividual variations. Incidence of micronuclei was also significantly increased compared to baseline control values. After short exposure of cultured lymphocytes to bleomycin, cells of occupationally exposed subjects responded with high numbers of chromatid breaks. Although the level of chromosome damage generated by bleomycin varied greatly between individuals, in exposed subjects a significantly elevated number of chromatid breaks was observed. Our results support data reported in literature indicating that microwave radiation represents a potential DNA-damaging hazard. Alkaline comet assay is confirmed as a sensitive and highly reproducible technique for detection of primary DNA damage inflicted in somatic cells. Micronucleus assay was confirmed as reliable bio-markers of effect and chromatid breakage assay as sensitive bio-marker of individual cancer susceptibility. The results obtained also confirm the necessity to improve measures and to perform accurate health surveillance of individuals occupationally exposed to microwave radiation

Assessing Software Quality Through Visualised Cohesion Metrics

Directory of Open Access Journals (Sweden)

Timothy Shih

2001-05-01

Full Text Available Cohesion is one of the most important factors for software quality as well as maintainability, reliability and reusability. Module cohesion is defined as a quality attribute that seeks for measuring the singleness of the purpose of a module. The module of poor quality can be a serious obstacle to the system quality. In order to design a good software quality, software managers and engineers need to introduce cohesion metrics to measure and produce desirable software. A highly cohesion software is thought to be a desirable constructing. In this paper, we propose a function-oriented cohesion metrics based on the analysis of live variables, live span and the visualization of processing element dependency graph. We give six typical cohesion examples to be measured as our experiments and justification. Therefore, a well-defined, well-normalized, well-visualized and well-experimented cohesion metrics is proposed to indicate and thus enhance software cohesion strength. Furthermore, this cohesion metrics can be easily incorporated with software CASE tool to help software engineers to improve software quality.

Scour in cohesive soils

Science.gov (United States)

2015-05-01

This study of scour in cohesive soils had two objectives. The first was to introduce and demonstrate a new ex situ erosion testing device (ESTD) that can mimic the near-bed flow of open channels to erode cohesive soils within a specified range of she...

Dynamics of Cohesive Sediments

DEFF Research Database (Denmark)

Johansen, Claus

The present thesis considers the transport processes of cohesive sediments. The cohesive sediment used in the laboratory experiments was kaolinite, a clay mineral, in order to be able to reproduce the individual experiments. In the first part of the thesis, the theoretical considerations regarding...

Force Transmission Modes of Non-Cohesive and Cohesive Materials at the Critical State.

Science.gov (United States)

Wang, Ji-Peng

2017-08-31

This paper investigates the force transmission modes, mainly described by probability density distributions, in non-cohesive dry and cohesive wet granular materials by discrete element modeling. The critical state force transmission patterns are focused on with the contact model effect being analyzed. By shearing relatively dense and loose dry specimens to the critical state in the conventional triaxial loading path, it is observed that there is a unique critical state force transmission mode. There is a universe critical state force distribution pattern for both the normal contact forces and tangential contact forces. Furthermore, it is found that using either the linear Hooke or the non-linear Hertz model does not affect the universe force transmission mode, and it is only related to the grain size distribution. Wet granular materials are also simulated by incorporating a water bridge model. Dense and loose wet granular materials are tested, and the critical state behavior for the wet material is also observed. The critical state strength and void ratio of wet granular materials are higher than those of a non-cohesive material. The critical state inter-particle distribution is altered from that of a non-cohesive material with higher probability in relatively weak forces. Grains in non-cohesive materials are under compressive stresses, and their principal directions are mainly in the axial loading direction. However, for cohesive wet granular materials, some particles are in tension, and the tensile stresses are in the horizontal direction on which the confinement is applied. The additional confinement by the tensile stress explains the macro strength and dilatancy increase in wet samples.

A CO-FISH assay to assess sister chromatid segregation patterns in mitosis of mouse embryonic stem cells.

Science.gov (United States)

Sauer, Stephan; Burkett, Sandra S; Lewandoski, Mark; Klar, Amar J S

2013-05-01

Sister chromatids contain identical DNA sequence but are chiral with respect to both their helical handedness and their replication history. Emerging evidence from various model organisms suggests that certain stem cells segregate sister chromatids nonrandomly to either maintain genome integrity or to bias cellular differentiation in asymmetric cell divisions. Conventional methods for tracing of old vs. newly synthesized DNA strands generally lack resolution for individual chromosomes and employ halogenated thymidine analogs with profound cytotoxic effects on rapidly dividing cells. Here, we present a modified chromosome orientation fluorescence in situ hybridization (CO-FISH) assay, where identification of individual chromosomes and their replication history is achieved in subsequent hybridization steps with chromosome-specific DNA probes and PNA telomere probes. Importantly, we tackle the issue of BrdU cytotoxicity and show that our method is compatible with normal mouse ES cell biology, unlike a recently published related protocol. Results from our CO-FISH assay show that mitotic segregation of mouse chromosome 7 is random in ES cells, which contrasts previously published results from our laboratory and settles a controversy. Our straightforward protocol represents a useful resource for future studies on chromatid segregation patterns of in vitro-cultured cells from distinct model organisms.

Team cohesion and team success in sport.

Science.gov (United States)

Carron, Albert V; Bray, Steven R; Eys, Mark A

2002-02-01

The main aim of this study was to examine the relationship between task cohesiveness and team success in elite teams using composite team estimates of cohesion. A secondary aim was to determine statistically the consistency (i.e. 'groupness') present in team members' perceptions of cohesion. Elite university basketball teams (n = 18) and club soccer teams (n = 9) were assessed for cohesiveness and winning percentages. Measures were recorded towards the end of each team's competitive season. Our results indicate that cohesiveness is a shared perception, thereby providing statistical support for the use of composite team scores. Further analyses indicated a strong relationship between cohesion and success (r = 0.55-0.67). Further research using multi-level statistical techniques is recommended.

Frequency of sister chromatid exchanges in lymphocyte cultures of human peripheral blood after the combined effect of γ-radiation and caffeine

International Nuclear Information System (INIS)

Nugis, V.Yu.; Pyatkin, E.K.

1986-01-01

Keeping of human peripheral blood lymphocytes, irradiated in vitro with 60 Co-γ-quanta at a dose of 3 Gy at G 0 phase, with caffeine of 16 and 160 μg/ml during cultivation with PHA had no appreciable influence on the fraquency of sister chromatid exchanges. A minor increase in the number of sister chromatid exchanges was only noted when nonirradiated and irradiated lymphocytes were cultured with 160 μg/ml caffeine

Cleavage of cohesin rings coordinates the separation of centrioles and chromatids.

Science.gov (United States)

Schöckel, Laura; Möckel, Martin; Mayer, Bernd; Boos, Dominik; Stemmann, Olaf

2011-07-10

Cohesin pairs sister chromatids by forming a tripartite Scc1-Smc1-Smc3 ring around them. In mitosis, cohesin is removed from chromosome arms by the phosphorylation-dependent prophase pathway. Centromeric cohesin is protected by shugoshin 1 and protein phosphatase 2A (Sgo1-PP2A) and opened only in anaphase by separase-dependent cleavage of Scc1 (refs 4-6). Following chromosome segregation, centrioles loosen their tight orthogonal arrangement, which licenses later centrosome duplication in S phase. Although a role of separase in centriole disengagement has been reported, the molecular details of this process remain enigmatic. Here, we identify cohesin as a centriole-engagement factor. Both premature sister-chromatid separation and centriole disengagement are induced by ectopic activation of separase or depletion of Sgo1. These unscheduled events are suppressed by expression of non-cleavable Scc1 or inhibition of the prophase pathway. When endogenous Scc1 is replaced by artificially cleavable Scc1, the corresponding site-specific protease triggers centriole disengagement. Separation of centrioles can alternatively be induced by ectopic cleavage of an engineered Smc3. Thus, the chromosome and centrosome cycles exhibit extensive parallels and are coordinated with each other by dual use of the cohesin ring complex.

Developing Indicators of Territorial Cohesion

DEFF Research Database (Denmark)

Gallina, Andrea; Farrugia, Nadia

setting. The concept of territorial cohesion attaches importance to the diversity of the European territory which is seen as a key competitive advantage, the preservation of the European social model, and the ability of the citizens of Europe's nations and regions to be able to continue to live within...... (EU). The objective of territorial cohesion, which builds on the European Spatial Development Perspective (ESDP), is to help achieve a more balanced development by reducing existing disparities, avoiding territorial imbalances and by making sectoral policies, which have a spatial impact and regional...... policy more coherent. It also aims to improve territorial integration and encourage cooperation between regions. Territorial cohesion complements the notions of economic and social cohesion by translating the fundamental EU goal of a balanced competitiveness and sustainable development into a territorial...

SeLeCT: a lexical cohesion based news story segmentation system

OpenAIRE

Stokes, Nicola; Carthy, Joe; Smeaton, Alan F.

2004-01-01

In this paper we compare the performance of three distinct approaches to lexical cohesion based text segmentation. Most work in this area has focused on the discovery of textual units that discuss subtopic structure within documents. In contrast our segmentation task requires the discovery of topical units of text i.e., distinct news stories from broadcast news programmes. Our approach to news story segmentation (the SeLeCT system) is based on an analysis of lexical cohesive strength between ...

Cohesion, Cracking, Dilation, and Flow -- Rheological Behavior of Cohesive Pharmaceutical Powders

Science.gov (United States)

Muzzio, Fernando

2007-03-01

Cohesive powders can be loosely defined as systems where the attractive forced between particles exceed the average particle weight. Cohesive powder flow is interesting from a wide range of reasons. Their main characteristic, intermittence, is evidenced both in the interruption of flow out of hoppers (a mundane issue causing great annoyance to industrial practitioners) and in the sudden avalanching of snow and dirt that has terrified and terrified mankind since the dawn of time. At the present time, our ability to predict either of these phenomena (and many more involving cohesive powders) is very limited, primarily due to an incomplete understanding of their constitutive behavior. To wit, consider just a simple fact: a flowing powder never has constant density. Equations describing the relationship between velocity, shear, stress, and density are rudimentary at best. Computational and experimental approaches for characterizing flow behavior are in their infancy. In this talk, I will describe some recent progress achieved at Rutgers by our group. New instruments have been developed to determine simultaneously powder density and cohesive flow effects. Extensive measurements have been carried out focusing on pharmaceutical blends. These results have been used to fine-tune computational models that accurately predict dilation, flow in drums, and flow in hoppers. Impact of these observations for pharmaceutical manufacturing applications will be discussed in some detail.

Transfer and Cohesion in Interdisciplinary Education

Directory of Open Access Journals (Sweden)

Søren Harnow Klausen

2014-06-01

Full Text Available One of the great challenges of interdisciplinary education is to create sufficient cohesion between disciplines. It is suggested that cohesion depends on the transfer of knowledge (in a broad sense, which includes skill and competences among the disciplines involved. Some of the most characteristic types of such transfer are identified and analyzed: Transfer of factual knowledge, theories, methods, models, skills, modes of collaboration and organization, meta-competences, disciplinary self-consciousness, problem selection, framework construction and motivation. Though some of these types of transfer may have a greater or smaller potential for creating cohesion, different kinds of cohesion may serve different interests, and there is no reason to assume that e.g. joint problem solving or theoretical integration should be more conducive to cohesion than e.g. contributions to motivation or disciplinary self-consciousness.

Influence of irradiation at different stages of mitotic cycle upon production of sister chromatid exchanges in cultured Chinese hamster cells

International Nuclear Information System (INIS)

Antoshina, M.M.; Poryadkova, N.A.; Luchnik, N.V.

1982-01-01

Frequency of sister chromatid exchanges (SCE) and microexchanges in Chinese hamster cells has been studied by means of the method of differential staining of chromatids on irradiation at different stages of the mitotic cycle. It is shown that the irradiation enhances frequency of SCE and microexchanges if it is carried out before the end of DNA replication synthesis. Comparison of frequency depenedence of radiation-induced microexchanges and SCE at different stages of the mitotic cycle results in the conclusion that the microexchanges are none other than small SCE

Sustaining exercise participation through group cohesion.

Science.gov (United States)

Estabrooks, P A

2000-04-01

The general hypothesis to be examined by this article is that increased group cohesion leads to an increase in adherence to an exercise program over time. Although preliminary research is promising, there is a need for further research aimed at examining the model of group development in exercise classes, the impact of group cohesion on both group and individual exercise behavior, and the measurement of group cohesion.

Photoreactivation of ultraviolet light-induced sister chromatid exchanges in potorous cells

International Nuclear Information System (INIS)

Ishizaki, K.; Nikaido, O.; Takebe, H.

1980-01-01

Exposure to visible light after UV-irradiation showed a remarkable effect on UV-induced sister chromatid exchanges (SCEs). After 6-h exposure to visible light (3 x 10 5 J/m 2 ), two-thirds of the UV-induced SCEs were prevented, confirming Kato's findings. (Nature 249, 552-3, 1974) Exposure to visible light before UV irradiation had no effect. This effect of visible light on UV-induced CSEs was temperature dependent, suggesting the presence of enzymatic photoreactivation. (author)

Effects of radiation on frequency of chromosomal aberrations and sister chromatid exchange in the benthic worm Neanthes arenaceodentata

International Nuclear Information System (INIS)

Harrison, F.L.; Rice, D.W. Jr.; Moore, D.H.; Varela, M.

1983-04-01

Traditional bioassays are unsuitable for assessing sublethal effects of low levels of radioactivity because mortality and phenotypic responses are not anticipated. We compared the usefulness of chromosomal aberration (CA) and sister chromatid exchange (SCE) induction as measures of low-level radiation effects in a sediment-dwelling marine worm, Neanthes arenaceodentata. Newly hatched larvae were exposed to two radiation exposure regimes. Groups of 100 larvae were exposed to either x rays delivered at high dose rates (0.7 Gy min -1 ) or to 60 Co gamma rays delivered at low dose rates (4.8 X 10 -5 to 1.2 X 10 -1 Gy h -1 ). After irradiation, the larvae were exposed to 3 X 10 -5 M bromodeoxyuridine (BrdUrd) for 28 h (x-ray-irradiated larvae) or for 54 h ( 60 Co-irradiated larvae). Slides of larval cells were prepared for observation of CAs and SCEs. Frequencies of CAs were determined in first division cells; frequencies of SCEs were determined in second division cells. Results from x-ray irradiation indicated that dose-related increases occur in chromosome and chromatid deletions, but an x-ray dose greater than or equal to 2 Gy was required to observe a significant increase. Worm larvae receiving 60 Co irradiation showed elevated SCE frequencies; a significant increase in SCE frequency was observed at 0.6 Gy. 49 references, 2 figures

The frequency of chromatide aberrations as a function of radiation dose estimated by the number of dicentrics found by the cytogenetic analysis of lymphocytes in subjects affected by the Chernobyl accident

International Nuclear Information System (INIS)

Nugis, V.Yu.; Chirkov, A.A.

1990-01-01

A study was made of the frequency of chromatide aberrations in lymphocyte culture of subjects affected by the Chernobyl accident as a function of dose estimated by the incidence of dicentrics. The average number of chromatide aberrations was nearly the same within the dose range from 0 to 5 Gy exhibiting a tendency towards growth with dose. A high individual variability of the chromatide aberration frequency was observed

Biochemical evidence for deficient DNA repair leading to enhanced G2 chromatid radiosensitivity and susceptibility to cancer

International Nuclear Information System (INIS)

Gantt, R.; Parshad, R.; Price, F.M.; Sanford, K.K.

1986-01-01

Human tumor cells and cells from cancer-prone individuals, compared with those from normal individuals, show a significantly higher incidence of chromatid breaks and gaps seen in metaphase cells immediately after G2 X irradiation. Previous studies with DNA repair-deficient mutants and DNA repair inhibitors strongly indicate that the enhancement results from a G2 deficiency(ies) in DNA repair. We report here biochemical evidence for a DNA repair deficiency that correlates with the cytogenetic studies. In the alkaline elution technique, after a pulse label with radioactive thymidine in the presence of 3-acetylaminobenzamide (a G2-phase blocker) and X irradiation, DNA from tumor or cancer-prone cells elutes more rapidly during the postirradiation period than that from normal cells. These results indicate that the DNA of tumor and cancer-prone cells either repairs more slowly or acquires more breaks than that of normal cells; breaks can accumulate during incomplete or deficient repair processes. The kinetic difference between normal and tumor or cancer-prone cells in DNA strand-break repair reaches a maximum within 2 h, and this maximum corresponds to the kinetic difference in chromatid aberration incidence following X irradiation reported previously. These findings support the concept that cells showing enhanced G2 chromatid radiosensitivity are deficient in DNA repair. The findings could also lead to a biochemical assay for cancer susceptibility

Separase Is Required for Homolog and Sister Disjunction during Drosophila melanogaster Male Meiosis, but Not for Biorientation of Sister Centromeres.

Science.gov (United States)

Blattner, Ariane C; Chaurasia, Soumya; McKee, Bruce D; Lehner, Christian F

2016-04-01

Spatially controlled release of sister chromatid cohesion during progression through the meiotic divisions is of paramount importance for error-free chromosome segregation during meiosis. Cohesion is mediated by the cohesin protein complex and cleavage of one of its subunits by the endoprotease separase removes cohesin first from chromosome arms during exit from meiosis I and later from the pericentromeric region during exit from meiosis II. At the onset of the meiotic divisions, cohesin has also been proposed to be present within the centromeric region for the unification of sister centromeres into a single functional entity, allowing bipolar orientation of paired homologs within the meiosis I spindle. Separase-mediated removal of centromeric cohesin during exit from meiosis I might explain sister centromere individualization which is essential for subsequent biorientation of sister centromeres during meiosis II. To characterize a potential involvement of separase in sister centromere individualization before meiosis II, we have studied meiosis in Drosophila melanogaster males where homologs are not paired in the canonical manner. Meiosis does not include meiotic recombination and synaptonemal complex formation in these males. Instead, an alternative homolog conjunction system keeps homologous chromosomes in pairs. Using independent strategies for spermatocyte-specific depletion of separase complex subunits in combination with time-lapse imaging, we demonstrate that separase is required for the inactivation of this alternative conjunction at anaphase I onset. Mutations that abolish alternative homolog conjunction therefore result in random segregation of univalents during meiosis I also after separase depletion. Interestingly, these univalents become bioriented during meiosis II, suggesting that sister centromere individualization before meiosis II does not require separase.

Induction of sister chromatid exchange in the presence of gadolinium-DTPA and its reduction by dimethyl sulfoxide

International Nuclear Information System (INIS)

Yamazaki, Etsuo; Fukuda, Hozumi; Shibuya, Hitoshi; Matsubara, Sho

1996-01-01

The authors investigate the frequency of sister chromatid exchange (SCE) after the addition of gadolinium (Gd)-DTPA to venous blood samples. Venous blood was obtained from nonsmokers. Samples were incubated with Gd-DTPA alone or in combination with mitomycin C, cytarabine, and dimethyl sulfoxide (DMSO), and then evaluated for SCEs. The frequency of SCE increased with the concentration of Gd-DTPA and as each chemotherapeutic agent was added. Sister chromatid exchange frequencies were lower when the blood was treated with a combination of Gd-DTPA and DMSO compared with Gd-DTPA alone. The increase in frequency of SCE seen after the addition of Gd-DTPA was decreased by the addition of DMSO, indicating the production of hydroxyl radicals. The effect likely is dissociation-related. 14 refs., 6 tabs

Auto consolidated cohesive sediments erosion

International Nuclear Information System (INIS)

Ternat, F.

2007-02-01

Pollutants and suspended matters of a river can accumulate into the sedimentary column. Once deposited, they are submitted to self-weight consolidation processes, ageing and burying, leading to an increase of their erosion resistance. Pollutant fluxes can be related to sedimentary fluxes, determined by threshold laws. In this work, an erosion threshold model is suggested by introducing a cohesion force into the usual force balance. A model of cohesion is developed on the basis of interactions between argillaceous cohesive particles (clays), particularly the Van der Waals force, whose parameterization is ensured by means of granulometry and porosity. Artificial erosion experiments were performed in a recirculating erosion flume with natural cored sediments where critical shear stress measurements were performed. Other analyses provided granulometry and porosity. The results obtained constitute a good database for the literature. The model is then applied to the experimental conditions and gives good agreement with measurements. An example of the accounting for self-weight consolidation processes is finally suggested, before finishing on a Mohr like diagram dedicated to soft cohesive sediment erosion. (author)

Winnowing and Flocculation in Bio-physical Cohesive Substrate: A Flume Experimental and Estuarine Study

Science.gov (United States)

Ye, L.; Parsons, D. R.; Manning, A. J.

2016-12-01

Cohesive sediment, or mud, is ubiquitously found in most aqueous environments, such as coasts and estuaries. The study of cohesive sediment behaviors requires the synchronous description of mutual interactions of grains (e.g., winnowing and flocculation), their physical properties (e.g., grain size) and also the ambient water. Herein, a series of flume experiments (14 runs) with different substrate mixtures of sand-clay-EPS (Extracellular Polymeric Substrates: secreted by aquatic microorganisms) are combined with an estuarine field survey (Dee estuary, NW England) to investigate the behavior of suspensions over bio-physical cohesive substrates. The experimental results indicate that winnowing and flocculation occur pervasively in bio-physical cohesive flow systems. Importantly however, the evolution of the bed and bedform dynamics and hence turbulence production can be lower when cohesivity is high. The estuarine survey also revealed that the bio-physical cohesion provided by both the clay and microorganism fractions in the bed, that pervasively exists in many natural estuarine systems, plays a significant role in controlling the interactions between bed substrate and sediment suspension and deposition, including controlling processes such as sediment winnowing, flocculation and re-deposition. Full understanding of these processes are essential in advancing sediment transport modelling and prediction studies across natural estuarine systems and the work will report on an improved conceptual model for sediment sorting deposition in bio-physical cohesive substrates.

Group cohesion, task performance, and the experimenter expectancy effect.

NARCIS (Netherlands)

Hoogstraten, J.; Vorst, H.C.M.

1978-01-01

Studied the effects of cohesion on task fulfillment and explored the influence of task fulfillment on the initial level of cohesion. Within 4-person groups of undergraduates, cohesion was manipulated successfully by a triple procedure. The level of cohesion was ascertained directly after the

Coaches' Perceptions of Team Cohesion in Paralympic Sports.

Science.gov (United States)

Falcão, William R; Bloom, Gordon A; Loughead, Todd M

2015-07-01

The purpose of this study was to investigate Paralympic coaches' perceptions of team cohesion. Seven head coaches of summer and winter Canadian Paralympic sport teams participated in the study. Four participants coached individual sports and 3 coached team sports. Data were collected using semistructured interviews and analyzed using thematic analysis. The results addressed the coaches' perceptions of cohesion in the Paralympic sport setting and strategies used to foster cohesion with their teams. Participants described using techniques and strategies for enhancing cohesion that were similar to those in nondisability sport, such as task-related activities, goal setting, and regularly communicating with their athletes. They also listed how cohesion was distinct to the Paralympic setting, such as the importance of interpersonal activities to build social cohesion. The implications of these results for coaching athletes with a disability are also presented.

The Effects Of Physical And Biological Cohesion On Bedforms

Science.gov (United States)

Parsons, D. R.; Schindler, R.; Baas, J.; Hope, J. A.; Malarkey, J.; Paterson, D. M.; Peakall, J.; Manning, A. J.; Ye, L.; Aspden, R.; Alan, D.; Bass, S. J.

2014-12-01

Most coastal sediments consist of complex mixtures of cohesionless sands, physically-cohesive clays and extra cellular polymeric substances (EPS) that impart biological cohesion. Yet, our ability to predict bedform dimensions in these substrates is reliant on predictions based exclusively on cohesionless sand. We present findings from the COHBED project - which explicitly examines how bedform dynamics are modified by natural cohesion. Our experimental results show that for ripples, height and length are inversely proportional to initial clay content and bedforms take longer to appear, with no ripples when clay content exceeds 18%. When clay is replaced by EPS the development time and time of first appearance of ripples both increase by two orders of magnitude, with no bedforms above 0.125% EPS. For dunes, height and length are also inversely proportional to initial substrate clay content, resulting in a transition from dunes to ripples normally associated with velocity decreases. Addition of low EPS concentrations into the substrate results in yet smaller bedforms at the same clay contents and at high EPS concentrations, biological cohesion supersedes all electrostatic bonding, and bedform size is no longer related to mud content. The contrast in physical and biological cohesion effects on bedform development result from the disparity between inter-particle electrostatic bonding of clay particles and EPS grain coating and strands that physically link sediments together, which effects winnowing rates as bedforms evolve. These findings have wide ranging implications for bedform predictions in both modern and ancient environments. Coupling of biological and morphological processes not only requires an understanding of how bedform dimensions influence biota and habitat, but also how benthic species can modify bedform dimensions. Consideration of both aspects provides a means in which fluid dynamics, sediment transport and ecosystem energetics can be linked to yield

Micromechanical modeling and inverse identification of damage using cohesive approaches

International Nuclear Information System (INIS)

Blal, Nawfal

2013-01-01

In this study a micromechanical model is proposed for a collection of cohesive zone models embedded between two each elements of a standard cohesive-volumetric finite element method. An equivalent 'matrix-inclusions' composite is proposed as a representation of the cohesive-volumetric discretization. The overall behaviour is obtained using homogenization approaches (Hashin Shtrikman scheme and the P. Ponte Castaneda approach). The derived model deals with elastic, brittle and ductile materials. It is available whatever the triaxiality loading rate and the shape of the cohesive law, and leads to direct relationships between the overall material properties and the local cohesive parameters and the mesh density. First, rigorous bounds on the normal and tangential cohesive stiffnesses are obtained leading to a suitable control of the inherent artificial elastic loss induced by intrinsic cohesive models. Second, theoretical criteria on damageable and ductile cohesive parameters are established (cohesive peak stress, critical separation, cohesive failure energy,... ). These criteria allow a practical calibration of the cohesive zone parameters as function of the overall material properties and the mesh length. The main interest of such calibration is its promising capacity to lead to a mesh-insensitive overall response in surface damage. (author) [fr

The Impact of Cooperative Video Games on Team Cohesion

Science.gov (United States)

Anderson, Greg

2010-01-01

In today's economy, productivity and efficiency require collaboration between employees. In order to improve collaboration the factors affecting teamwork must be examined to identify where changes can be made in order to increase performance. One factor contributing to teamwork is team cohesion and represents a process whereby members are joined…

Relationship between group cohesion and anxiety in soccer.

Science.gov (United States)

Borrego, Carla Chicau; Cid, Luis; Silva, Carlos

2012-10-01

Group cohesion in sport is a widely spread theme today. Research has found cohesion to be influenced by several individual and group components. Among the cognitive variables that relate to cohesion we found competitive anxiety. The purpose of this study was to examine the relation between task cohesion (ATG-T, and GI-T) and competitive state anxiety (A-state), and also if there would be a relation between cohesion and self-confidence. Participants were 366 football players of both genders male and female, aged between 15 to 23 years old, from Portugal's championships. Cohesion was measured using the Portuguese version of the Group Environment Questionnaire, and to assess competitive anxiety, we used the Portuguese version of the Competition State Anxiety Inventory 2. Our results show that female athletes report experiencing more cognitive anxiety and less self-confidence than male athletes. Only cognitive anxiety relates in a significantly negative way with the perception of cohesion (GI-T e ATG-T) in the total number of participants and in male athletes. Relatively to the somatic anxiety, it only relates negatively with the perception of the integration of the group in the total number of participants and in the male gender.

Environmental cohesion across the Hungarian-Croatian border

OpenAIRE

Varjú Viktor

2016-01-01

Environmental cohesion (as a new EU paradigm for a place-based interpretation of environmental justice) has a clear connection to territorial cohesion. Based on this idea, advantages for people can include an equitable distribution of environmental protection and access to environmental services. In non-EU countries regional environmental cohesion is used as an instrument to accelerate accession to the EU and it may be manifested as a declaration of environ...

Groupthink: one peril of group cohesiveness.

Science.gov (United States)

Rosenblum, E H

1982-04-01

A group's aim is to make well-conceived, well-understood, well-accepted and realistic decisions to reach their agreed-upon goals. This aim applies equally to their own goals and those occasionally imposed by outsiders such as hospital administration, accreditation committees and the federal government. Effective groupwork requires group cohesion with its components of trust, risk taking, mutual support, and group esteem. With constant vigilance the group can maintain its positive dynamics, so that the unhealthy state of groupthink does not undermine its existence.

Cohesive zone model for direct silicon wafer bonding

Science.gov (United States)

Kubair, D. V.; Spearing, S. M.

2007-05-01

Direct silicon wafer bonding and decohesion are simulated using a spectral scheme in conjunction with a rate-dependent cohesive model. The cohesive model is derived assuming the presence of a thin continuum liquid layer at the interface. Cohesive tractions due to the presence of a liquid meniscus always tend to reduce the separation distance between the wafers, thereby opposing debonding, while assisting the bonding process. In the absence of the rate-dependence effects the energy needed to bond a pair of wafers is equal to that needed to separate them. When rate-dependence is considered in the cohesive law, the experimentally observed asymmetry in the energetics can be explained. The derived cohesive model has the potential to form a bridge between experiments and a multiscale-modelling approach to understand the mechanics of wafer bonding.

INTANGIBLE ASSETS THROUGH THE COHESION POLICY

Directory of Open Access Journals (Sweden)

Popescu (Stingaciu Ana-Maria

2012-07-01

Full Text Available INTANGIBLE ASSETS THROUGH THE COHESION POLICY Roth Anne-Marie-Monika West University of Timisoara Faculty of Economics and Business Administration Popescu (Stingaciu Ana-Maria West University of Timisoara Faculty of Economics and Business Administration Intangible assets in general and intellectual capital in particular are important to both society and organizations. It can be a source of competitive advantage for business and stimulate innovation that leads to wealth generation. Technological revolutions, the rise of the knowledge-based economy and the networked society have all led to the same conclusion that intangibles and how they contribute to value creation have to be appreciated so that the appropriate decisions can be made to protect and enhance them. The Cohesion Policy represents the main EU measure to ensure a balanced and sustainable growth in Europe by promoting harmonious development and reducing the regional disparities. The general objective of the paper is to highlight the important role of the Cohesion Policy in the development of intangible assets. The objectives and the instruments of the Cohesion Policy are designed to support programs on regional development, economic change, enhanced competitiveness and territorial cooperation through the European Union, to develop human resources and employability. Keywords: intangible assets, intellectual capital, Cohesion policy, development; JEL Classification: O43, G32, D24, O34

The roles of cohesins in mitosis, meiosis, and human health and disease

Science.gov (United States)

Brooker, Amanda S.; Berkowitz, Karen M.

2015-01-01

Summary Mitosis and meiosis are essential processes that occur during development. Throughout these processes, cohesion is required to keep the sister chromatids together until their separation at anaphase. Cohesion is created by multi-protein subunit complexes called cohesins. Although the subunits differ slightly in mitosis and meiosis, the canonical cohesin complex is composed of four subunits that are quite diverse. The cohesin complexes are also important for DNA repair, gene expression, development, and genome integrity. Here we provide an overview of the roles of cohesins during these different events, as well as their roles in human health and disease, including the cohesinopathies. Although the exact roles and mechanisms of these proteins are still being elucidated, this review will serve as a guide for the current knowledge of cohesins. PMID:24906316

Education and Social Cohesion: Higher Education

Science.gov (United States)

Moiseyenko, Olena

2005-01-01

Social cohesion is understood as the social networks and the norms of reciprocity and trustworthiness that arise from connections among individuals. When students attend higher education institutions, they go through a process of socialization, and it is vital to ensure that they acquire the core values that underpin the social cohesion. This…

Sequence Classification: 890748 [

Lifescience Database Archive (English)

Full Text Available in, involved in maintaining sister chromatid cohesion during meiosis I as well as promoting proper attachmen...t of kinetochores to the spindle during meiosis I and meiosis II; Spo13p || http://www.ncbi.nlm.nih.gov/protein/6321802 ...

Kinetics of chromatid aberrations in G2 ataxia-telangiectasia cells exposed to X-rays and ara A

International Nuclear Information System (INIS)

Mozdarani, Hossein; Bryant, P.E.

1989-01-01

The cytogenetic effects of X-rays alone or in combination with 9-β-D-arabinofuranosyladenine (ara A) were studied in an immortalized fibroblastic line of ataxia-telangiectasia (A-T) cells. It is postulated that the kinetics of disappearance (rejoining) of chromatid deletions with postirradiation incubation time reflects the underlying repair of dsb, and is inhibited by ara A. The rejoining kinetics for deletions in A-T was similar to that found in a previous study of normal human fibroblasts (Mozdarani and Bryant 1987). The number of deletions in X-irradiated A-T cells at 1.5 h before fixation was found to be higher by a factor of approximately 2 than that found previously in normals, indicating that in A-T a higher rate of conversion of dsb into chromatid deletions occurs. The frequency of exchanges induced in G2 A-T cells was similarly enhanced but, unlike the situation in normal cells, ara A was found to cause only a slight increase in this frequency. (author)

Psychobiological Assessment and Enhancement of Team Cohesion and Psychological Resilience in ROTC Cadets Using a Virtual-Reality Team Cohesion Test

Science.gov (United States)

2016-06-01

Using a Virtual - Reality Team Cohesion Test PRINCIPAL INVESTIGATOR: Josh Woolley MD/PhD CONTRACTING ORGANIZATION: NORTHERN CALIFORNIA INSTITUTE SAN...Team Cohesion and Psychological Resilience in ROTC Cadets Using a Virtual - Reality Team Cohesion Test 5b. GRANT NUMBER W81XWH-15-1-0042 5c. PROGRAM...targets while flying a virtual air vehicle. No individual has access to all the necessary information or controls, so operating as a team is crucial

A proposal of a standardised nomenclature for terminal minute sister chromatid exchanges

Directory of Open Access Journals (Sweden)

Máximo E. Drets

2006-01-01

Full Text Available We described spontaneous minute sister chromatid exchanges (SCE in telomeric regions of human and Chinese hamster ovary (CHO chromosomes more than 10 years ago. These structures, which we called t-SCE, were detected by means of highly precise quantitative microphotometrical scanning and computer graphic image analysis. Recently, several authors using the CO-FISH method also found small SCEs in telomeric regions and called them T-SCE. The use of different terms for designating the same phenomenon should be avoided. We propose ter SCE as a uniform nomenclature for minute telomeric SCEs.

Natural disasters and indicators of social cohesion.

Science.gov (United States)

Calo-Blanco, Aitor; Kovářík, Jaromír; Mengel, Friederike; Romero, José Gabriel

2017-01-01

Do adversarial environmental conditions create social cohesion? We provide new answers to this question by exploiting spatial and temporal variation in exposure to earthquakes across Chile. Using a variety of methods and controlling for a number of socio-economic variables, we find that exposure to earthquakes has a positive effect on several indicators of social cohesion. Social cohesion increases after a big earthquake and slowly erodes in periods where environmental conditions are less adverse. Our results contribute to the current debate on whether and how environmental conditions shape formal and informal institutions.

Cohesion energetics of carbon allotropes: Quantum Monte Carlo study

Energy Technology Data Exchange (ETDEWEB)

Shin, Hyeondeok; Kang, Sinabro; Koo, Jahyun; Lee, Hoonkyung; Kwon, Yongkyung, E-mail: ykwon@konkuk.ac.kr [Division of Quantum Phases and Devices, School of Physics, Konkuk University, Seoul 143-701 (Korea, Republic of); Kim, Jeongnim, E-mail: jnkim@ornl.gov [Materials Science and Technology Division and Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831 (United States)

2014-03-21

We have performed quantum Monte Carlo calculations to study the cohesion energetics of carbon allotropes, including sp{sup 3}-bonded diamond, sp{sup 2}-bonded graphene, sp–sp{sup 2} hybridized graphynes, and sp-bonded carbyne. The computed cohesive energies of diamond and graphene are found to be in excellent agreement with the corresponding values determined experimentally for diamond and graphite, respectively, when the zero-point energies, along with the interlayer binding in the case of graphite, are included. We have also found that the cohesive energy of graphyne decreases systematically as the ratio of sp-bonded carbon atoms increases. The cohesive energy of γ-graphyne, the most energetically stable graphyne, turns out to be 6.766(6) eV/atom, which is smaller than that of graphene by 0.698(12) eV/atom. Experimental difficulty in synthesizing graphynes could be explained by their significantly smaller cohesive energies. Finally, we conclude that the cohesive energy of a newly proposed graphyne can be accurately estimated with the carbon–carbon bond energies determined from the cohesive energies of graphene and three different graphynes considered here.

Cohesion Energetics of Carbon Allotropes: Quantum Monte Carlo Study

Energy Technology Data Exchange (ETDEWEB)

Shin, Hyeondeok [Konkuk University, South Korea; Kang, Sinabro [Konkuk University, South Korea; Koo, Jahyun [Konkuk University, South Korea; Lee, Hoonkyung [Konkuk University, South Korea; Kim, Jeongnim [ORNL; Kwon, Yongkyung [Konkuk University, South Korea

2014-01-01

We have performed quantum Monte Carlo calculations to study the cohesion energetics of carbon allotropes, including sp3-bonded diamond, sp2-bonded graphene, sp-sp2 hybridized graphynes, and sp-bonded carbyne. The comput- ed cohesive energies of diamond and graphene are found to be in excellent agreement with the corresponding values de- termined experimentally for diamond and graphite, respectively, when the zero-point energies, along with the interlayer binding in the case of graphite, are included. We have also found that the cohesive energy of graphyne decreases system- atically as the ratio of sp-bonded carbon atoms increases. The cohesive energy of -graphyne, the most energetically- stable graphyne, turns out to be 6.766(6) eV/atom, which is smaller than that of graphene by 0.698(12) eV/atom. Experi- mental difficulty in synthesizing graphynes could be explained by their significantly smaller cohesive energies. Finally we conclude that the cohesive energy of a newly-proposed two-dimensional carbon network can be accurately estimated with the carbon-carbon bond energies determined from the cohesive energies of graphene and three different graphynes.

RPA Mediates Recruitment of MRX to Forks and Double-Strand Breaks to Hold Sister Chromatids Together.

Science.gov (United States)

Seeber, Andrew; Hegnauer, Anna Maria; Hustedt, Nicole; Deshpande, Ishan; Poli, Jérôme; Eglinger, Jan; Pasero, Philippe; Gut, Heinz; Shinohara, Miki; Hopfner, Karl-Peter; Shimada, Kenji; Gasser, Susan M

2016-12-01

The Mre11-Rad50-Xrs2 (MRX) complex is related to SMC complexes that form rings capable of holding two distinct DNA strands together. MRX functions at stalled replication forks and double-strand breaks (DSBs). A mutation in the N-terminal OB fold of the 70 kDa subunit of yeast replication protein A, rfa1-t11, abrogates MRX recruitment to both types of DNA damage. The rfa1 mutation is functionally epistatic with loss of any of the MRX subunits for survival of replication fork stress or DSB recovery, although it does not compromise end-resection. High-resolution imaging shows that either the rfa1-t11 or the rad50Δ mutation lets stalled replication forks collapse and allows the separation not only of opposing ends but of sister chromatids at breaks. Given that cohesin loss does not provoke visible sister separation as long as the RPA-MRX contacts are intact, we conclude that MRX also serves as a structural linchpin holding sister chromatids together at breaks. Copyright © 2016 Elsevier Inc. All rights reserved.

Territorial cohesion post - 2013 : To whomsoever it may concern

NARCIS (Netherlands)

Faludi, A.K.F.

2010-01-01

Conceived as a motion for resolution, the paper considers territorial cohesion now being on the statute book, the Green Paper on Territorial Cohesion, Barca making the case for integrated, place-based strategies, the EU Strategy for the Baltic Sea Region and the future of Cohesion policy. The

Written cohesion in children with and without language learning disabilities.

Science.gov (United States)

Koutsoftas, Anthony D; Petersen, Victoria

2017-09-01

Cohesion refers to the linguistic elements of discourse that contribute to its continuity and is an important element to consider as part of written language intervention, especially in children with language learning disabilities (LLD). There is substantial evidence that children with LLD perform more poorly than typically developing (TD) peers on measures of cohesion in spoken language and on written transcription measures; however, there is far less research comparing groups on cohesion as a measure of written language across genres. The current study addresses this gap through the following two aims. First, to describe and compare cohesion in narrative and expository writing samples of children with and without language learning disabilities. Second, to relate measures of cohesion to written transcription and translation measures, oral language, and writing quality. Fifty intermediate-grade children produced one narrative and one expository writing sample from which measures of written cohesion were obtained. These included the frequency, adequacy and complexity of referential and conjunctive ties. Expository samples resulted in more complex cohesive ties and children with TD used more complex ties than peers with LLD. Different relationships among cohesion measures and writing were observed for narrative verse expository samples. Findings from this study demonstrate cohesion as a discourse-level measure of written transcription and how the use of cohesion can vary by genre and group (LLD, TD). Clinical implications for assessment, intervention, and future research are provided. © 2016 Royal College of Speech and Language Therapists.

The association between status and cohesion in sport teams.

Science.gov (United States)

Jacob, C S; Carron, A V

1998-02-01

The main objective of this study was to establish the relationship between perceptions of status attributes and cohesion and status ranking and cohesion. A secondary aim was to determine whether age (operationalized by scholastic levels) or culture serves as a moderator in the relationship between either status attributes or status ranking and cohesion. Another secondary aim was to determine if differences are present in the importance attached by athletes to status attributes. Canadian and Indian athletes were tested. Although perceptions of the importance of status attributes and cohesiveness were related, the effect size was small (Green, 1991); perceptions of status ranking and cohesiveness were not related. Neither scholastic level nor culture served as a moderator in the association between either status attributes or status rank and cohesion. The importance that athletes attach to status attributes is similar between scholastic levels and across cultures. The results are discussed in terms of the role of status in sport teams.

Development of an evaluation method for fracture mechanical tests on small samples based on a cohesive zone model

International Nuclear Information System (INIS)

Mahler, Michael

2016-01-01

The safety and reliability of nuclear power plants of the fourth generation is an important issue. It is based on a reliable interpretation of the components for which, among other fracture mechanical material properties are required. The existing irradiation in the power plants significantly affects the material properties which therefore need to be determined on irradiated material. Often only small amounts of irradiated material are available for characterization. In that case it is not possible to manufacture sufficiently large specimens, which are necessary for fracture mechanical testing in agreement with the standard. Small specimens must be used. From this follows the idea of this study, in which the fracture toughness can be predicted with the developed method based on tests of small specimens. For this purpose, the fracture process including the crack growth is described with a continuum mechanical approach using the finite element method and the cohesive zone model. The experiments on small specimens are used for parameter identification of the cohesive zone model. The two parameters of the cohesive zone model are determined by tensile tests on notched specimens (cohesive stress) and by parameter fitting to the fracture behavior of smalls specimens (cohesive energy). To account the different triaxialities of the specimens, the cohesive stress is used depending on the triaxiality. After parameter identification a large specimen can be simulated with the cohesive zone parameters derived from small specimens. The predicted fracture toughness of this big specimen fulfills the size requirements in the standard (ASTM E1820 or ASTM E399) in contrast to the small specimen. This method can be used for ductile and brittle material behavior and was validated in this work. In summary, this method offers the possibility to determine the fracture toughness indirectly based on small specimen testing. Main advantage is the low required specimen volume. Thereby massively

Ultraviolet-induced formation of micronuclei and sister chromatid exchange in cultured fibroblasts of patients with cutaneous malignant melanoma

International Nuclear Information System (INIS)

Roser, M.; Boehm, A.O.; Oldigs, M.; Weichenthal, M.; Reimers, U.; Schmidt-Preuss, U.; Breitbart, E.W.; Ruediger, H.W.

1989-01-01

Genetically enhanced sensitivity to ultraviolet (UV) radiation may play an important role in the development of cutaneous malignant melanoma (CMM). This was studied in cultured fibroblasts of 26 CMM patients and controls by micronucleus (MN) test and sister chromatid exchange (SCE) after UV irradiation (375 J/m2). Sister chromatid exchange and MN formation were used as parameters to detect the UV-induced genotoxic damage in the individual cell strains. We found that the UV-induced level of MN was significantly increased in CMM patients (p = 0.0005), being most pronounced in the familial cases (p = 0.0001). Ultraviolet-induced SCE was also elevated in CMM patients (p = 0.001), but there was no difference between familial and nonfamilial cases. The present findings indicate that genetic predisposition contributes to the development of CMM in a subset of CMM patients and may be due to an enhanced susceptibility to UV light

Why are Rich Countries more Politically Cohesive?

DEFF Research Database (Denmark)

Dalgaard, Carl-Johan Lars; Olsson, Ola

of other groups in society. If the gains from specialization become sufficiently large, however, a market economy will emerge. From being essentially non-cohesive under self-sufficiency, the political decision making process becomes cohesive in the market economy, as the welfare of individuals...

Justice and Social Cohesion: Some conservative perspectives

DEFF Research Database (Denmark)

Pedersen, Søren Hviid

2011-01-01

In the wake of recent debates on multiculturalism and value-pluralism, the pressing questions now focuses on whether social cohesion and the notion of justice are sustainable and can be upheld, at least from a European perspective. There are many theoretical and academic responses, mainly from...... liberals, on how to accommodate the different demands of various ethnic and religious groups and at the same time sustain a minimum of social cohesion and justice. One voice is missing and that is a conservative perspective. The purpose of this paper is to formulate a modern conservative analysis...... of this problem. The argument presented in this paper will, first, take its point of departure from David Hume’s notion of sympathy and how this makes social cohesion possible. Second, it will be argued that social cohesion is a prerequisite for the existence of justice, and therefore justice is a derivative...

Chiasmata promote monopolar attachment of sister chromatids and their co-segregation toward the proper pole during meiosis I.

Directory of Open Access Journals (Sweden)

Yukinobu Hirose

2011-03-01

Full Text Available The chiasma is a structure that forms between a pair of homologous chromosomes by crossover recombination and physically links the homologous chromosomes during meiosis. Chiasmata are essential for the attachment of the homologous chromosomes to opposite spindle poles (bipolar attachment and their subsequent segregation to the opposite poles during meiosis I. However, the overall function of chiasmata during meiosis is not fully understood. Here, we show that chiasmata also play a crucial role in the attachment of sister chromatids to the same spindle pole and in their co-segregation during meiosis I in fission yeast. Analysis of cells lacking chiasmata and the cohesin protector Sgo1 showed that loss of chiasmata causes frequent bipolar attachment of sister chromatids during anaphase. Furthermore, high time-resolution analysis of centromere dynamics in various types of chiasmate and achiasmate cells, including those lacking the DNA replication checkpoint factor Mrc1 or the meiotic centromere protein Moa1, showed the following three outcomes: (i during the pre-anaphase stage, the bipolar attachment of sister chromatids occurs irrespective of chiasma formation; (ii the chiasma contributes to the elimination of the pre-anaphase bipolar attachment; and (iii when the bipolar attachment remains during anaphase, the chiasmata generate a bias toward the proper pole during poleward chromosome pulling that results in appropriate chromosome segregation. Based on these results, we propose that chiasmata play a pivotal role in the selection of proper attachments and provide a backup mechanism that promotes correct chromosome segregation when improper attachments remain during anaphase I.

Molecular Intercalation and Cohesion of Organic Bulk Heterojunction Photovoltaic Devices

KAUST Repository

Bruner, Christopher; Miller, Nichole C.; McGehee, Michael D.; Dauskardt, Reinhold H.

2013-01-01

The phase separated bulk heterojunction (BHJ) layer in BHJ polymer:fullerene organic photovoltaic devices (OPV) are mechanically weak with low values of cohesion. Improved cohesion is important for OPV device thermomechanical reliability. BHJ devices are investigated and how fullerene intercalation within the active layer affects cohesive properties in the BHJ is shown. The intercalation of fullerenes between the side chains of the polymers poly(3,3″′-didocecyl quaterthiophene) (PQT-12) and poly(2,5-bis(3-hexadecylthiophen-2-yl)thieno[3,2-b]thiophene (pBTTT) is shown to enhance BHJ layer cohesion. Cohesion values range from ≈1 to 5 J m -2, depending on the polymer:fullerene blend, processing conditions, and composition. Devices with non-intercalated BHJ layers are found to have significantly reduced values of cohesion. The resulting device power conversion efficiencies (PCE) are also investigated and correlated with the device cohesion. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Molecular Intercalation and Cohesion of Organic Bulk Heterojunction Photovoltaic Devices

KAUST Repository

Bruner, Christopher

2013-01-17

The phase separated bulk heterojunction (BHJ) layer in BHJ polymer:fullerene organic photovoltaic devices (OPV) are mechanically weak with low values of cohesion. Improved cohesion is important for OPV device thermomechanical reliability. BHJ devices are investigated and how fullerene intercalation within the active layer affects cohesive properties in the BHJ is shown. The intercalation of fullerenes between the side chains of the polymers poly(3,3″′-didocecyl quaterthiophene) (PQT-12) and poly(2,5-bis(3-hexadecylthiophen-2-yl)thieno[3,2-b]thiophene (pBTTT) is shown to enhance BHJ layer cohesion. Cohesion values range from ≈1 to 5 J m -2, depending on the polymer:fullerene blend, processing conditions, and composition. Devices with non-intercalated BHJ layers are found to have significantly reduced values of cohesion. The resulting device power conversion efficiencies (PCE) are also investigated and correlated with the device cohesion. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

The ATPases of cohesin interface with regulators to modulate cohesin-mediated DNA tethering

Science.gov (United States)

Çamdere, Gamze; Guacci, Vincent; Stricklin, Jeremiah; Koshland, Douglas

2015-01-01

Cohesin tethers together regions of DNA, thereby mediating higher order chromatin organization that is critical for sister chromatid cohesion, DNA repair and transcriptional regulation. Cohesin contains a heterodimeric ATP-binding Cassette (ABC) ATPase comprised of Smc1 and Smc3 ATPase active sites. These ATPases are required for cohesin to bind DNA. Cohesin’s DNA binding activity is also promoted by the Eco1 acetyltransferase and inhibited by Wpl1. Recently we showed that after cohesin stably binds DNA, a second step is required for DNA tethering. This second step is also controlled by Eco1 acetylation. Here, we use genetic and biochemical analyses to show that this second DNA tethering step is regulated by cohesin ATPase. Furthermore, our results also suggest that Eco1 promotes cohesion by modulating the ATPase cycle of DNA-bound cohesin in a state that is permissive for DNA tethering and refractory to Wpl1 inhibition. DOI: http://dx.doi.org/10.7554/eLife.11315.001 PMID:26583750

Cohesion as interaction in ELF spoken discourse

Directory of Open Access Journals (Sweden)

T. Christiansen

2013-10-01

Full Text Available Hitherto, most research into cohesion has concentrated on texts (usually written only in standard Native Speaker English – e.g. Halliday and Hasan (1976. By contrast, following on the work in anaphora of such scholars as Reinhart (1983 and Cornish (1999, Christiansen (2011 describes cohesion as an interac­tive process focusing on the link between text cohesion and discourse coherence. Such a consideration of cohesion from the perspective of discourse (i.e. the process of which text is the product -- Widdowson 1984, p. 100 is especially relevant within a lingua franca context as the issue of different variations of ELF and inter-cultural concerns (Guido 2008 add extra dimensions to the complex multi-code interaction. In this case study, six extracts of transcripts (approximately 1000 words each, taken from the VOICE corpus (2011 of conference question and answer sessions (spoken interaction set in multicultural university con­texts are analysed in depth by means of a qualitative method.

Cell-stage-specific enhancement by caffeine of the frequency of chromatid aberrations induced by X-rays in neutral ganglia of Drosophila melanogaster

International Nuclear Information System (INIS)

De Marco, A.; Polani, S.

1981-01-01

Caffeine (10 -2 M) induced a high level of chromatid aberrations in neural ganglia of third-instar larvae of Drosophila melanogaster only when it was added to cells in late G 2 and mitotic prophase. No aberrations were observed after treatment in late S-middle G 2 or C-mitosis. We observed that, in these stages, caffeine strongly increased X-ray-induced damage (500 R). This potentiation was quantitatively similar. But it involved all types of aberration after treatment in C-mitosis, and essentially isochromatid deletions and chromatid exhanges after treatment in S-G 2 . Some hypotheses are put forth to explain the possible mechanism of action of caffeine in the potentiation of X-ray-induced damage. (orig.)

Neighborhood cohesion, neighborhood disorder, and cardiometabolic risk.

Science.gov (United States)

Robinette, Jennifer W; Charles, Susan T; Gruenewald, Tara L

2018-02-01

Perceptions of neighborhood disorder (trash, vandalism) and cohesion (neighbors trust one another) are related to residents' health. Affective and behavioral factors have been identified, but often in studies using geographically select samples. We use a nationally representative sample (n = 9032) of United States older adults from the Health and Retirement Study to examine cardiometabolic risk in relation to perceptions of neighborhood cohesion and disorder. Lower cohesion is significantly related to greater cardiometabolic risk in 2006/2008 and predicts greater risk four years later (2010/2012). The longitudinal relation is partially accounted for by anxiety and physical activity. Copyright © 2017 Elsevier Ltd. All rights reserved.

Phenotypic variability in 49 cases of ESCO2 mutations, including novel missense and codon deletion in the acetyltransferase domain, correlates with ESCO2 expression and establishes the clinical criteria for Roberts syndrome

DEFF Research Database (Denmark)

Vega, H; Trainer, A H; Gordillo, M

2010-01-01

Roberts syndrome (RBS) and SC phocomelia are caused by mutations in ESCO2, which codes for an acetyltransferase involved in the regulation of sister chromatid cohesion. Of 26 mutations described to date, only one missense mutation has been reported and all others are predicted to be truncating...

Phenotypic variability in 49 cases of ESCO2 mutations, including novel missense and codon deletion in the acetyltransferase domain, correlates with ESCO2 expression and establishes the clinical criteria for Roberts syndrome

NARCIS (Netherlands)

Vega, H.; Trainer, A.H.; Gordillo, M.; Crosier, M.; Kayserili, H.; Skovby, F.; Uzielli, M.L.G.; Schnur, R.E.; Manouvrier, S.; Blair, E.; Hurst, J.A.; Forzano, F.; Meins, M.; Simola, K.O.J.; Raas-Rothschild, A; Hennekam, R.C.M.; Jabs, E.W.

2010-01-01

Background Roberts syndrome (RBS) and SC phocomelia are caused by mutations in ESCO2, which codes for an acetyltransferase involved in the regulation of sister chromatid cohesion. Of 26 mutations described to date, only one missense mutation has been reported and all others are predicted to be

DNA Catenation Maintains Structure of Human Metaphase Chromosomes

DEFF Research Database (Denmark)

L. V. Bauer, David; Marie, Rodolphe; Rasmussen, Kristian Hagsted

2012-01-01

Mitotic chromosome structure is pivotal to cell division but difficult to observe in fine detail using conventional methods. DNA catenation has been implicated in both sister chromatid cohesion and chromosome condensation, but has never been observed directly. We have used a lab-on-a-chip microfl...

Estimating cohesion in small groups using audio-visual nonverbal behavior

NARCIS (Netherlands)

Hung, H.; Gatica-Perez, D.

2010-01-01

Cohesiveness in teams is an essential part of ensuring the smooth running of task-oriented groups. Research in social psychology and management has shown that good cohesion in groups can be correlated with team effectiveness or productivity, so automatically estimating group cohesion for team

[Family cohesion associated with oral health, socioeconomic factors and health behavior].

Science.gov (United States)

Ferreira, Luale Leão; Brandão, Gustavo Antônio Martins; Garcia, Gustavo; Batista, Marília Jesus; Costa, Ludmila da Silva Tavares; Ambrosano, Gláucia Maria Bovi; Possobon, Rosana de Fátima

2013-08-01

Overall health surveys have related family cohesion to socio-economic status and behavioral factors. The scope of this study was to investigate the association between family cohesion and socio-economic, behavioral and oral health factors. This was a, cross-sectional study with two-stage cluster sampling. The random sample consisted of 524 adolescents attending public schools in the city of Piracicaba-SP. Variables were evaluated by self-applied questionnaires and caries and periodontal disease were assessed by DMF-T and CPI indices. The adolescent's perception of family cohesion was assessed using the family adaptability and cohesion scale. Univariate and multinomial logistic regression shows that adolescents with low family cohesion were more likely than those with medium family cohesion to have low income (OR 2,28 95% CI 1,14- 4,55), presence of caries (OR 2,23 95% CI 1,21-4,09), less than two daily brushings (OR 1,91 95% CI 1,03-3,54). Adolescents with high family cohesion were more likely than those with medium family cohesion to have high income and protective behavior against the habit of smoking. Thus, the data shows that adolescent perception of family cohesion was associated with behavioral, socio-economic and oral health variables, indicating the importance of an integral approach to patient health.

An examination of the cohesion-performance relationship in university hockey teams.

Science.gov (United States)

Slater, M R; Sewell, D F

1994-10-01

The objective of this study was to assess, using the Group Environment Questionnaire, whether team cohesion in university-level field hockey was a cause for, or an effect of, successful performance. A quasi-experimental longitudinal design with cross-lagged correlational analysis was adopted and measures of cohesion and performance were taken midway and later in the season. The results of the synchronous correlations showed a positive relationship (with good stationarity) between team cohesion and performance outcome. Although non-significant cross-lagged differentials indicated a circular relationship, the magnitudes of both the cross-lagged correlations and the partial correlations, together with multiple-regression analyses, revealed that the stronger flow was from cohesion to performance. The socially oriented aspects of cohesion, in particular, had significant associations with performance. The results imply that cohesion-performance relationships should be examined within a circular model, in which cohesion and performance are interdependent.

Mutagen-induced sister chromatid exchanges in xeroderma pigmentosum and normal lymphocytes

International Nuclear Information System (INIS)

Perry, P.E.; Jager, M.; Evans, H.J.

1978-01-01

The induction of sister chromatid exchanges (SCE), by ultra-violet irradiation and by three chemical mutagens that differ in the type of repair response that they elicit, has been compared in lymphocytes from a control and from an individual suffering from the DNA excision repair deficiency syndrome, xeroderma pigmentosum (XP). The XP lymphocytes were found to be more sensitive in terms of SCE response, not only to UV irradiation, but also to all of the chemicals studied. The results indicate that the abnormality of DNA repair in this XP patient is expressed not only in the defective excision of thymine dimers, or other UV photoproducts, but also in a reduced ability to repair other types of DNA lesion. (author)

Cohesion and Hierarchy in Physically Abusive Families

Directory of Open Access Journals (Sweden)

Clarissa De Antoni

2009-06-01

Full Text Available This paper investigates cohesion (emotional bonding and hierarchy (powerstructure in families with abuse against their children. Twenty low-incomefamilies participated. Father, mother and child’s perspective of family relations(cohesion and hierarchy were evaluated by the Family System Test(FAST. The relationship between father-child, mother-child, couple, andamong siblings were evaluated at typical and conflictive situations. Resultsshow a significance regarding to cohesion in typical and conflictive situationfor father-child and mother-child dyads in all perspectives (by father, mother,and child. There is no significant differences regarding to hierarchy. Theseresults suggest that the families see the intrafamilial violence as a constant,since they cannot differentiate between both situations.

The effect of biological cohesion on current ripple development

Science.gov (United States)

Malarkey, Jonathan; Baas, Jaco H.; Hope, Julie

2014-05-01

Results are presented from laboratory experiments examining the role of biological cohesion, associated with Extra Polymeric Substances, on the development of current ripples. The results demonstrate the importance of biological cohesion compared to the effect of physical cohesion associated with clays in an otherwise sandy bed. FURTHER INFORMATION In fluvial and marine environments sediment transport is mainly dependent on the nature of the bed surface (rippled or flat) and the nature of cohesion in the bed. Cohesion can be either physical, as a result of the presence of clays, or biological as a result of the presence of organisms. In the case of the latter, biological cohesion occurs as a result of the presence of Extra Polymeric Substances (EPS) secreted by microorganisms. While it is known that EPS can dramatically increase the threshold of motion (Grant and Gust, 1987), comparatively little is known about the effect of EPS on ripple formation and development. The experiments described here seek to fill this gap. They also allow the effect of biological cohesion to be compared with that of physical cohesion from previous experiments (Baas et al., 2013). The experiments, which were conducted in a 10m flume at Bangor University, involved a current over a bed made of fine sand, with a median diameter of 0.148mm, and various amounts of xanthan gum, a proxy for naturally occurring EPS (Vardy et al., 2007). The hydrodynamic experimental conditions were matched very closely to those of Baas et al. (2013). The ripple dimensions were recorded through the glass side wall of the tank using time lapse photography. In the physical cohesion experiments of Baas et al. (2013) for clay contents up to 12%, the clay was very quickly winnowed out of the bed, leaving essentially clay-free ripples that developed at more or less the same rate as clean sand ripples. The resulting equilibrium ripples were essentially the same length as the clean sand ripples but reduced in height. By

Determination of mode-I cohesive strength for interfaces

DEFF Research Database (Denmark)

Jørgensen, J. B.; Thouless, M. D.; Sørensen, Bent F.

2016-01-01

The cohesive strength is one of the governing parameters controlling crack deflection at interfaces, but measuring its magnitude is challenging. In this paper, we demonstrate a novel approach to determine the mode-I cohesive strength of an interface by using a 4-point single-edge-notch beam...... in response to this stress, before the main crack starts to grow. Observations using 2D digital-image correlation showed that an ''apparent" strain across the interface initially increases linearly with the applied load, but becomes nonlinear upon the initiation of the interface crack. The cohesive strength...

Barossa Night: cohesion in the British Army officer corps.

Science.gov (United States)

Bury, Patrick

2017-06-01

Contrasting the classical explanation of military group cohesion as sustained by interpersonal bonds, recent scholars have highlighted the importance of ritualized communication, training and drills in explaining effective military performance in professional armies. While this has offered a welcome addition to the cohesion literature and a novel micro-sociological method of examining cohesion, its primary evidential base has been combat groups. Indeed, despite their prominent role in directing operations over the past decade, the British Army's officer corps has received relatively little attention from sociologists during this period. No attempt has been made to explain cohesion in the officer corps. Using a similar method to recent cohesion scholars, this paper seeks to address this imbalance by undertaking a micro-sociology of one ritual in particular: 'Barossa Night' in the Royal Irish Regiment. Firstly, it draws on the work of Durkheim to examine how cohesion amongst the officer corps is created and sustained through a dense array of practises during formal social rituals. It provides evidence that the use of rituals highlights that social solidarity is central to understanding officer cohesion. Secondly, following Hockey's work on how private soldiers negotiate order, the paper shows how this solidarity in the officer corps is based on a degree of negotiated order and the need to release organizational tensions inherent in a strictly hierarchical rank structure. It highlights how the awarding of gallantry medals can threaten this negotiated order and fuel deviancy. In examining this behaviour, the paper shows that even amongst an officer class traditionally viewed as the elite upholders of organizational discipline, the negotiation of rank and hierarchy can be fluid. How deviant behaviour is later accepted and normalized by senior officers indicates that negotiated order is as important to understanding cohesion in the British Army's officer corps as it is

Frequencies of chromosomal aberrations and sister chromatid exchanges in the benthic worm Neanthes arenaceodentata exposed to ionizing radiation

International Nuclear Information System (INIS)

Harrison, F.L.; Rice, D.W. Jr.; Moore, D.H.

1984-07-01

Traditional bioassays are unsuitable for assessing sublethal effects from ocean disposal of low-level radioactive waste because mortality and phenotypic responses are not anticipated. We compared the usefulness of chromosomal aberration and sister chromatid exchange (SCE) induction as measures of low-level radiation effects in a sediment-dwelling marine worm, Neanthes arenaceodentata. The SCEs, in contrast to chromosomal aberrations, do not alter the overall chromosome morphology and in mammalian cells appear to be a more sensitive indicator of DNA alterations caused by environmental mutagens. Newly hatched larvae were exposed to two radiation-exposure regimes of either x rays at a high dose rate of 0.7 Gy (70 rad)/min for as long as 5.5 min or to 60 Co gamma rays at a low dose rate of from 4.8 x 10 -5 to 1.2 x 10 -1 Gy (0.0048 to 12 rad)/h for 24 h. After irradiation, the larvae were exposed to 3 x 10 -5 M bromodeoxyuridine (BrdUrd) for 28 h (x-ray-irradiated larvae) or for 54 h ( 60 Co-irradiated larvae). Larval cells were examined for the proportion of cells in first, second, and third or greater division. Frequencies of chromosomal aberrations and SCEs were determined in first and second division cells, respectively. Results from x-ray irradiation indicated that dose-related increases occur in chromosome and chromatid deletions, but a dose of equal or greater 2 Gy (equal to or greater than 200 rad) was required to observe a significant increase. Worm larvae receiving 60 Co irradiation showed elevated SCE frequencies with a significant increase of 0.6 Gy (60 rad). We suggest that both SCEs and chromosomal aberrations may be useful for measuring effects on genetic material induced by radiation. 56 references, 7 figures, 9 tables

INTERACTIVE EFFECTS OF TEAM COHESION ON PERCEIVED EFFICACY IN SEMI-PROFESSIONAL SPORT

Directory of Open Access Journals (Sweden)

Francisco Miguel Leo Marcos

2010-06-01

Full Text Available The present study examined the relationships among cohesion, self-efficacy, coaches' perceptions of their players' efficacy at the individual level and athletes' perceptions of their teammates' efficacy. Participants (n = 76 recruited from four semi- professional soccer and basketball teams completed cohesiveness and efficacy questionnaires who. Data were analyzed through a correlational methodology. Results indicated significant correlations between self-efficacy and task cohesion and social cohesion. Regression analysis results suggest task cohesion positively related to coaches and teammate´s perception of efficacy. These results have implications for practitioners in terms of the importance of team building to enhance team cohesion and feelings of efficacy

Grain-resolving simulations of settling cohesive sediment

Science.gov (United States)

Vowinckel, Bernhard; Whithers, Jade; Meiburg, Eckart; Luzzatto-Fegiz, Paolo

2017-11-01

Cohesive sediment is ubiquitous in natural environments such as rivers, lakes and coastal ecosystems. For this type of sediment, we can no longer ignore the short-range attractive forces that result in flocculation of aggregates much larger than the individual grain size. Hence, understanding the complex dynamics of the interplay between flocculated sediment and the ambient fluid is of prime interest for managing aquatic environments, although a comprehensive understanding of these phenomena is still lacking. In the present study, we address this issue by carrying out grain-resolved simulations of cohesive particles settling under gravity using the Immersed Boundary Method. We present a computational model formulation to accurately resolve the process of flocculation. The cohesive model is then applied to a complex test case. A randomly distributed ensemble of 1261 polydisperse particles is released in a tank of quiescent fluid. Subsequently, particles start to settle, thereby replacing fluid at the bottom of the tank, which induces a counter flow opposing the settling direction. This mechanism will be compared to experimental studies from the literature, as well as to the non-cohesive counterpart to assessthe impact of flocculation on sedimentation.

Smc1β is required for activation of SAC during mouse oocyte meiosis.

Science.gov (United States)

Miao, Yilong; Zhou, Changyin; Cui, Zhaokang; Dai, Xiaoxin; Zhang, Mianqun; Lu, Yajuan; Xiong, Bo

2017-03-19

Smc1β is a meiosis-specific cohesin subunit that is essential for sister chromatid cohesion and DNA recombination. Previous studies have shown that Smc1β-deficient mice in both sexes are sterile. Ablation of Smc1β during male meiosis leads to the blockage of spermatogenesis in pachytene stage, and ablation of Smc1β during female meiosis generates a highly error-prone oocyte although it could develop to metaphase II stage. However, the underlying mechanisms regarding how Smc1β maintains the correct meiotic progression in mouse oocytes have not been clearly defined. Here, we find that GFP-fused Smc1β is expressed and localized to the chromosomes from GV to MII stages during mouse oocyte meiotic maturation. Knockdown of Smc1β by microinjection of gene-specific morpholino causes the impaired spindle apparatus and chromosome alignment which are highly correlated with the defective kinetochore-microtubule attachments, consequently resulting in a prominently higher incidence of aneuploid eggs. In addition, the premature extrusion of polar bodies and escape of metaphase I arrest induced by low dose of nocodazole treatment in Smc1β-depleted oocytes indicates that Smc1β is essential for activation of spindle assembly checkpoint (SAC) activity. Collectively, we identify a novel function of Smc1β as a SAC participant beyond its role in chromosome cohesion during mouse oocyte meiosis.

Relationship of DNA repair to chromosome aberrations, sister-chromatid exchanges and survival during liquid-holding recovery in X-irradiated mammalian cells

International Nuclear Information System (INIS)

Fornace, A.J. Jr.; Nagasawa, H.; Little, J.B.

1980-01-01

The repair of X-ray-induced DNA single strand breaks and DNA-protein cross-links was investigated in stationary phase, contact-inhibited mouse cells by the alkaline-elution technique. Approx. 90% of X-ray-induced single strand breaks were rejoined during the first hour of repair, whereas most of the remaining breaks were rejoined more slowly during the next 5 h. At early repair times, the number of residual non-rejoined sungle strand breaks was approx. proportional to the X-ray dose. DNA-protein cross-links were removed at a slower rate (Tsub(1/2) approx. 10-12 h). Cells were held in stationary growth for various periods of time after irradiation before subculture at low density to score for colony survival (potentially lethal damage repair), chromosome aberrations in the first mitosis, and sister-chromatid exchanges in the second mitosis. Both cell killing and the frequency of chromosome aberrations decreased during the first several hours of recovery, reaching a minimum level by 6 h; this decrease correlated temporally with the repair of the slowly rejoining DNA-strand breaks. Relatively few sister-chromatid exchanges were observed when the cells were subcultured immediately after X-ray. The exchange frequency rose to maximum levels after a 4-h recovery interval, and returned to control levels after 12 h of recovery. The possible relationship of DNA repair to these changes in survival, chromosome aberrations, and sister-chromatid exchanges during liquid-holding recovery is discussed. (orig.)

Chromosome variant 1qh− and its influence on the 3D organization ...

Indian Academy of Sciences (India)

2014-04-21

Apr 21, 2014 ... protein for sister chromatid cohesion during S phase, is char- ... tansky in 1860, the mechanisms responsible for the disease ... the Ethics Review Committee on Human Research of the ... somes 1 with equal size of heterochromatic segments in a healthy control subject (A1) .... But, literature reports about the.

Sister chromatid exchange analysis and chromosoma aberration studies in interventional cardiology laboratory workers. One year follow up study

International Nuclear Information System (INIS)

Erol, M.K.; Oztas, S.; Bozkurt, E.; Karakelleoglu, S.

2002-01-01

Invasive cardiology laboratory workers are occupationally exposed to chronic ionizing radiation. It is known that ionizing radiation has a damaging effect on chromosomes. In present study, we investigated the frequency of sister chromatid exchange (SCE) and chromosomal aberrations in 11 invasive cardiology laboratory workers and 11 healthy controls. After a vacation period, we took blood samples for chromosome analysis in months 0, 4, 8 and 12 (last two month period was the nonradiation time). The SCE frequencies did not change significantly after exposure to ionizing radiation in any worker. Our study has revealed that non-specific structural chromosome aberrations such as gaps, isogaps, acentric chromosomes, chromatids and chromosome breakage could be in the 4th and 8th months after ionizing radiation exposure in the metaphase plaques. All abnormal chromosomal effects had disappeared by the end of the two month non-exposure period in each worker. In conclusion, the results suggest that SCE frequencies are not significantly affected in invasive cardiology laboratory workers who are exposed occupationally to ionizing radiation, although some degree of reversible chromosomal aberrations did appear. (author)

Pier and contraction scour prediction in cohesive soils at selected bridges in Illinois

Science.gov (United States)

Straub, Timothy D.; Over, Thomas M.

2010-01-01

This report presents the results of testing the Scour Rate In Cohesive Soils-Erosion Function Apparatus (SRICOS-EFA) method for estimating scour depth of cohesive soils at 15 bridges in Illinois. The SRICOS-EFA method for complex pier and contraction scour in cohesive soils has two primary components. The first component includes the calculation of the maximum contraction and pier scour (Zmax). The second component is an integrated approach that considers a time factor, soil properties, and continued interaction between the contraction and pier scour (SRICOS runs). The SRICOS-EFA results were compared to scour prediction results for non-cohesive soils based on Hydraulic Engineering Circular No. 18 (HEC-18). On average, the HEC-18 method predicted higher scour depths than the SRICOS-EFA method. A reduction factor was determined for each HEC-18 result to make it match the maximum of three types of SRICOS run results. The unconfined compressive strength (Qu) for the soil was then matched with the reduction factor and the results were ranked in order of increasing Qu. Reduction factors were then grouped by Qu and applied to each bridge site and soil. These results, and comparison with the SRICOS Zmax calculation, show that less than half of the reduction-factor method values were the lowest estimate of scour; whereas, the Zmax method values were the lowest estimate for over half. A tiered approach to predicting pier and contraction scour was developed. There are four levels to this approach numbered in order of complexity, with the fourth level being a full SRICOS-EFA analysis. Levels 1 and 2 involve the reduction factors and Zmax calculation, and can be completed without EFA data. Level 3 requires some surrogate EFA data. Levels 3 and 4 require streamflow for input into SRICOS. Estimation techniques for both EFA surrogate data and streamflow data were developed.

Cohesion in Online Student Teams versus Traditional Teams

Science.gov (United States)

Hansen, David E.

2016-01-01

Researchers have found that the electronic methods in use for online team communication today increase communication quality in project-based work situations. Because communication quality is known to influence group cohesion, the present research examined whether online student project teams are more cohesive than traditional teams. We tested…

Investigating the settling dynamics of cohesive silt particles with particle-resolving simulations

Science.gov (United States)

Sun, Rui; Xiao, Heng; Sun, Honglei

2018-01-01

The settling of cohesive sediment is ubiquitous in aquatic environments, and the study of the settling process is important for both engineering and environmental reasons. In the settling process, the silt particles show behaviors that are different from non-cohesive particles due to the influence of inter-particle cohesive force. For instance, the flocs formed in the settling process of cohesive silt can loosen the packing, and thus the structural densities of cohesive silt beds are much smaller than that of non-cohesive sand beds. While there is a consensus that cohesive behaviors depend on the characteristics of sediment particles (e.g., Bond number, particle size distribution), little is known about the exact influence of these characteristics on the cohesive behaviors. In addition, since the cohesive behaviors of the silt are caused by the inter-particle cohesive forces, the motions of and the contacts among silt particles should be resolved to study these cohesive behaviors in the settling process. However, studies of the cohesive behaviors of silt particles in the settling process based on particle-resolving approach are still lacking. In the present work, three-dimensional settling process is investigated numerically by using CFD-DEM (Computational Fluid Dynamics-Discrete Element Method). The inter-particle collision force, the van der Waals force, and the fluid-particle interaction forces are considered. The numerical model is used to simulate the hindered settling process of silt based on the experimental setup in the literature. The results obtained in the simulations, including the structural densities of the beds, the characteristic lines, and the particle terminal velocity, are in good agreement with the experimental observations in the literature. To the authors' knowledge, this is the first time that the influences of non-dimensional Bond number and particle polydispersity on the structural densities of silt beds have been investigated separately

A Reappraisal of Lexical Cohesion in Conversational Discourse

Science.gov (United States)

Gomez Gonzalez, Maria De Los Angeles

2013-01-01

Cohesion, or the connectedness of discourse, has been recognized as playing a crucial role in both language production and comprehension processes. Researchers have debated about the "right" number and classification of cohesive devices, as well as about their interaction with coherence and/or genre. The present study proposes an integrative model…

Anisotropy in cohesive, frictional granular media

International Nuclear Information System (INIS)

Luding, Stefan

2005-01-01

The modelling of cohesive, frictional granular materials with a discrete particle molecular dynamics is reviewed. From the structure of the quasi-static granular solid, the fabric, stress, and stiffness tensors are determined, including both normal and tangential forces. The influence of the material properties on the flow behaviour is also reported, including relations between the microscopic attractive force and the macroscopic cohesion as well as the dependence of the macroscopic friction on the microscopic contact friction coefficient. Related to the dynamics, the anisotropy of both structure and stress are exponentially approaching the maximum

Emerging technologies, innovative teachers and moral cohesion

CSIR Research Space (South Africa)

Batchelor, J

2012-05-01

Full Text Available efficacy when they engage with emerging technologies. The concept of moral cohesion is further expanded and forms the main focus of this article. Keywords: emerging technologies, innovative teachers, moral cohesion, pedagogies, ethics, teacher.... African Renaissance and teacher disposition is identified as the strongest drivers. Teacher training forms the link between the strong drivers and the outcomes manifest as Stewardship and ethical considerations. 3.2 Professional Burden The theme...

Britishness and Community Cohesion in Muslim News Online

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Hassen ZRIBA

2013-12-01

Full Text Available The issues of British national identity and social cohesion have become pressing concerns within the multicultural fabric of contemporary British society. The increasing number of immigrants and their offspring, along with the maintenance of their cultural roots, seem to represent a serious defiance to social cohesion and the alleged “purity” of Britishness. A number of race related reports were produced by the official authorities to churn out the necessary steps to be followed by the British (immigrants and host community in order to keep social stability and community cohesion. Thus, the politics of community cohesion came to the fore as the neologism of contemporary British political discourse. Such new discourse of governance has been digested and processed differently by different mass media. It has been decoded, for instance, preferably by mainstream news agencies like BBC News Online. However, arguably, it is read appositionally or at best negotiatedly by ethnicity-related news agencies such as Muslim News Online. In this article, attempt has been made to adopt media discourse analysis tools to decipher the ways Muslim News Online decoded and then encoded the hegemonic official discourses of Britishness and community cohesion. A critical and interpretative approach is used to accomplish such study. The corpus of this study is primarily extracted from the website of the Muslim News Online.

Effect of clay type on the velocity and run-out distance of cohesive sediment gravity flows

Science.gov (United States)

Baker, Megan; Baas, Jaco H.; Malarkey, Jonathan; Kane, Ian

2016-04-01

to produce similar run-out distances and maximum head velocities. Strongly cohesive bentonite flows were able to create a stronger network of particle bonds than weakly cohesive kaolinite flows of a similar concentration, thus producing the lower maximum head velocities and run-out distances observed. The lack of cohesion in the silica-flour laden flows meant that extremely high suspended sediment concentrations, i.e. close to the cubic packing density, were required to produce a high enough frictional strength to reduce the forward momentum of these flows. These experimental results can be used to improve our understanding of the deposit geometry and run-out distance of fine-grained SGFs in the natural environment. We suggest that natural SGFs that carry weakly cohesive clays (e.g. kaolinite) reach a greater distance from their origin than flows that contain strongly cohesive clays (e.g. bentonite) at similar suspended sediment concentrations, whilst equivalent fine-grained, non-cohesive SGFs travel the furthest. In addition, weakly cohesive SGFs may cover a larger surface area and have thinner deposits, with important ramifications for the architecture of stacked event beds.

Design of Normal Concrete Mixtures Using Workability-Dispersion-Cohesion Method

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Hisham Qasrawi

2016-01-01

Full Text Available The workability-dispersion-cohesion method is a new proposed method for the design of normal concrete mixes. The method uses special coefficients called workability-dispersion and workability-cohesion factors. These coefficients relate workability to mobility and stability of the concrete mix. The coefficients are obtained from special charts depending on mix requirements and aggregate properties. The method is practical because it covers various types of aggregates that may not be within standard specifications, different water to cement ratios, and various degrees of workability. Simple linear relationships were developed for variables encountered in the mix design and were presented in graphical forms. The method can be used in countries where the grading or fineness of the available materials is different from the common international specifications (such as ASTM or BS. Results were compared to the ACI and British methods of mix design. The method can be extended to cover all types of concrete.

Microzonation Analysis of Cohesionless and Cohesive Soil

Directory of Open Access Journals (Sweden)

Tan Choy Soon

2017-01-01

Full Text Available Urban seismic risk is a continuous worldwide issue, numerous researchers are putting great effort in dealing with how to minimise the level of the threat. The only way to minimise the social and economic consequences caused but the seismic risk is through comprehensive earthquake scenario analysis such as ground response analysis. This paper intends to examine the characteristic of shear wave velocity and peak ground acceleration on cohesionless and cohesiveness soil. In order to examine the characteristic of shear wave velocity and peak ground acceleration on cohesionless and cohesiveness soil, ground response analysis was performed using Nonlinear Earthquake Site Response Analysis (NERA and Equivalent-linear Earthquake Site Response Analysis (EERA. The value of ground acceleration was initially high at bedrock and vanishes during the propagation process. It is thus, the measured acceleration at surface is therefore much lower as compare to at bedrock. Result shows that seismic waves can travel faster in harder soil as compared to softer soil. Cohesive soil contributes more to the shaking amplification than cohesionless soil such as sand and harder soil. This is known as local site effect. The typical example is the Mexico Earthquake that happened in 1985. As conclusion, peak ground acceleration for cohesive soil is higher than in cohesionless soil.

Determining mode I cohesive law of Pinus pinaster by coupling double cantilever beam test with digital image correlation

Directory of Open Access Journals (Sweden)

J. Xavier

2015-01-01

Full Text Available The direct identification of the cohesive law in pure mode I of Pinus pinaster is addressed. The approach couples the double cantilever beam (DCB test with digital image correlation (DIC. Wooden beam specimens loaded in the radial-longitudinal (RL fracture propagation system are used. The strain energy release rate in mode I ( is uniquely determined from the load-displacement ( curve by means of the compliance-based beam method (CBBM. This method relies on the concept of equivalent elastic crack length ( and therefore does not require the monitoring of crack propagation during test. The crack tip opening displacement in mode I is determined from the displacement field at the initial crack tip. The cohesive law in mode I is then identified by numerical differentiation of the relationship. Moreover, the proposed procedure is validated by finite element analyses including cohesive zone modelling. It is concluded that the proposed data reduction scheme is adequate for assessing the cohesive law in pure mode I of P. pinaster

Rotational Failure of Rubble-pile Bodies: Influences of Shear and Cohesive Strengths

Science.gov (United States)

Zhang, Yun; Richardson, Derek C.; Barnouin, Olivier S.; Michel, Patrick; Schwartz, Stephen R.; Ballouz, Ronald-Louis

2018-04-01

The shear and cohesive strengths of a rubble-pile asteroid could influence the critical spin at which the body fails and its subsequent evolution. We present results using a soft-sphere discrete element method to explore the mechanical properties and dynamical behaviors of self-gravitating rubble piles experiencing increasing rotational centrifugal forces. A comprehensive contact model incorporating translational and rotational friction and van der Waals cohesive interactions is developed to simulate rubble-pile asteroids. It is observed that the critical spin depends strongly on both the frictional and cohesive forces between particles in contact; however, the failure behaviors only show dependence on the cohesive force. As cohesion increases, the deformation of the simulated body prior to disruption is diminished, the disruption process is more abrupt, and the component size of the fissioned material is increased. When the cohesive strength is high enough, the body can disaggregate into similar-size fragments, which could be a plausible mechanism to form asteroid pairs or active asteroids. The size distribution and velocity dispersion of the fragments in high-cohesion simulations show similarities to the disintegrating asteroid P/2013 R3, indicating that this asteroid may possess comparable cohesion in its structure and experience rotational fission in a similar manner. Additionally, we propose a method for estimating a rubble pile’s friction angle and bulk cohesion from spin-up numerical experiments, which provides the opportunity for making quantitative comparisons with continuum theory. The results show that the present technique has great potential for predicting the behaviors and estimating the material strengths of cohesive rubble-pile asteroids.

Long Fibre Composite Modelling Using Cohesive User's Element

International Nuclear Information System (INIS)

Kozak, Vladislav; Chlup, Zdenek

2010-01-01

The development glass matrix composites reinforced by unidirectional long ceramic fibre has resulted in a family of very perspective structural materials. The only disadvantage of such materials is relatively high brittleness at room temperature. The main micromechanisms acting as toughening mechanism are the pull out, crack bridging, matrix cracking. There are other mechanisms as crack deflection etc. but the primer mechanism is mentioned pull out which is governed by interface between fibre and matrix. The contribution shows a way how to predict and/or optimise mechanical behaviour of composite by application of cohesive zone method and write user's cohesive element into the FEM numerical package Abaqus. The presented results from numerical calculations are compared with experimental data. Crack extension is simulated by means of element extinction algorithms. The principal effort is concentrated on the application of the cohesive zone model with the special traction separation (bridging) law and on the cohesive zone modelling. Determination of micro-mechanical parameters is based on the combination of static tests, microscopic observations and numerical calibration procedures.

Interactive effects of team cohesion on perceived efficacy in semi-professional sport.

Science.gov (United States)

Marcos, Francisco Miguel Leo; Miguel, Pedro Antonio Sánchez; Oliva, David Sánchez; Calvo, Tomás García

2010-01-01

The present study examined the relationships among cohesion, self-efficacy, coaches' perceptions of their players' efficacy at the individual level and athletes' perceptions of their teammates' efficacy. Participants (n = 76) recruited from four semi- professional soccer and basketball teams completed cohesiveness and efficacy questionnaires who. Data were analyzed through a correlational methodology. Results indicated significant correlations between self-efficacy and task cohesion and social cohesion. Regression analysis results suggest task cohesion positively related to coaches and teammate's perception of efficacy. These results have implications for practitioners in terms of the importance of team building to enhance team cohesion and feelings of efficacy. Key pointsThis paper increases the knowledge about soccer and basketball match analysis.Give normative values to establish practice and match objectives.Give applications ideas to connect research with coaches' practice.

Understanding Social Cohesion Differences in Common Interest Housing Developments

NARCIS (Netherlands)

Dam, van R.I.; Eshuis, J.; Twist, van M.J.W.; Anquetil, V.

2014-01-01

The worldwide upsurge of common interest housing developments (CIDs) has stirred up debates regarding community development and social cohesion. Critics have argued that CIDs lack social cohesion because people regulate the community via rules and contracts rather than through social relationships

Anaphoric Referencing: A Cohesive Device in Written and Spoken ...

African Journals Online (AJOL)

unique firstlady

cohesive function "if and when they can be interpreted through their relation to some other (explicit) encoding device in the same passage". ... is Anaphoric but when the implicit term precedes its linguistic referent, the cohesive tie is known as ...

Substitution as a Device of Grammatical Cohesion in English Contexts

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Mohammad Reza Hasannejad

2012-05-01

Full Text Available The present study set out to investigate the effect of teaching substitution as a kind of grammatical cohesion on the true identification of confusing substitution elements with cohesive or non-cohesive roles in different contexts and also the production of modal, reporting and conditional contexts through clausal substitution acquaintance. To this end, the following procedures were taken. First 120 male and female EFL students were selected from Iranshahr Azad University. Having administered the language proficiency test, researchers selected 80 students as intermediate subjects according to their TOEFL band scores. First, pretests of cohesion identification (substitution and production of modal, reporting and conditional environments were administered to both control and experimental groups. Then, the experimental group was exposed to the teaching of the above-said above-mentioned cohesive device. Finally, post-tests of substitution elements’ identification and modal, reporting and conditional contexts’ production through clausal substitution familiarity were administered. The results showed that cohesive device treatment helped students on the true identification of substitution elements. Another finding proved that EFL students might have no difficulty in learning certain rules or classification of rules and application of their clausal substitution knowledge in creating modal, reporting and conditional contexts. Our findings can have implications for the field of language learning and teaching.

Group cohesion in sports teams of different professional level

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Vazha M. Devishvili

2017-12-01

Full Text Available Background. Team sports are not only the most exciting sporting events. but also complex activities that make serious demands on players. The effectiveness of the team depends not only on the high level of gaming interaction. but also on the relationship between the players. The work is based on the material of sports teams and is devoted to the study of the phenomenon of group cohesion. As a basic model. the authors choose a 4-factor model that describes cohesion in sports teams. The paper also considered the phenomenon of the emergence of the aggregate subject in the process of joint activity. when the participants feel themselves as a whole and experience feelings of satisfaction and a surge of energy. Objective. The main objective of the work is to investigate the relationship between the level of team cohesion and subjective feelings of unity of its players. As additional variables in the study there is a sport (football and volleyball and team level (amateur and professional. To test the assumptions. two methods were used (the Sport Team Cohesion Questionnaire and the Subject Unity Index. which allow not only to determine the overall level of cohesion and unity. but also to reveal the structure of both phenomena. The study involved two men’s volleyball and two men’s football teams of different ages: 8-9 years (39 athletes; 12-14 years (24 athletes and 18-25 years (41 athletes. Design. For amateur groups represented by children’s and teenage sports teams. significant correlations between unity and unity were obtained (r = 0.618. p <0.01; r = 0.477. p <0.05. For professional teams. no significant correlations were found. Influence of the sport on cohesion is also different for amateur and professional teams. In the first case. the cohesion is higher for football players (U = 118. p <0.05. and in the second case for volleyball players (U = 124. p <0.05. Results. The findings indicate that the professional level of players affects group

Adsorption induced losses in interfacial cohesion

International Nuclear Information System (INIS)

Asaro, R.J.

1977-07-01

A model for interfacial cohesion is developed which describes the loss in the strength of an interface due to the segregation and adsorption of impurities on it. Distinctions are made between interface separations that occur too rapidly for any significant redistribution of adsorbing matter to take place and separations that are slow enough to allow full adsorption equilibrium. Expressions for the total work of complete decohesion are presented for both cases. The results are applied to well-known model adsorption isotherms and some experimental data for grain boundary adsorption of phosphorus in iron is analyzed with respect to the losses in intergranular cohesion

Are diverse societies less cohesive? Testing contact and mediated contact theories.

Science.gov (United States)

McKenna, Sarah; Lee, Eunro; Klik, Kathleen A; Markus, Andrew; Hewstone, Miles; Reynolds, Katherine J

2018-01-01

Previous research has demonstrated that there is a negative relationship between ethnic diversity in a local community and social cohesion. Often the way social cohesion is assessed, though, varies across studies and only some aspects of the construct are included (e.g., trust). The current research explores the relationship between diversity and social cohesion across a number of indicators of social cohesion including neighbourhood social capital, safety, belonging, generalized trust, and volunteering. Furthermore, social psychological theories concerning the role of positive contact and its impact on feelings of threat are investigated. Using a sample of 1070 third generation 'majority' Australians and structural equation modelling (SEM), findings suggest ethnic diversity is related to positive intergroup contact, and that contact showed beneficial impacts for some indicators of social cohesion both directly and indirectly through reducing perceived threat. When interethnic contact and perceived threat are included in the model there is no direct negative effect between diversity and social cohesion. The theoretical implications of these findings are outlined including the importance of facilitating opportunities for positive contact in diverse communities.

Sister-chromatid exchange induced by X-ray of human lymphocytes and the effect of L-crysteine

International Nuclear Information System (INIS)

Abramovski, I.; Vorsanger, G.; Hirschhorn, K.

1978-01-01

A staining technique that detects sister-chromatid exchanges (SCEs) has been used to examine the response of human lymphocyte chromosomes to various dosages of X-irradiation. The SCE frequency was markedly increased following irradiation. However, the increase was of a significantly smaller magnitude when irradiation occurred in the presence of an antimutagenic agent. Scoring SCEs may provide a useful technique for assaying the mutagenic effects of environmental carcinogens as well as the protective effects of antimutagenic agents. (Auth.)

Cohesive cracked-hinge model for simulation of fracture in one-way slabs on grade

DEFF Research Database (Denmark)

Skar, Asmus; Poulsen, Peter Noe; Olesen, John Forbes

2017-01-01

Numerical analysis of slab on grade structures subjected to mechanical loads is a complex matter often requiring computationally expensive models. In order to develop a simplified and general concept for non-linear analysis of slab on grade structures, this paper presents a cohesive cracked-hinge...

Personality in teams: its relationship to social cohesion, task cohesion, and team performance

NARCIS (Netherlands)

van Vianen, A.E.M.; de Dreu, C.K.W.

2001-01-01

This study continued past research on the relationship between personality composition in teams and social cohesion and team performance (Barrick, Stewart, Neubert, & Mount, 1998). Results from the Barrick et al. sample (N = 50) were compared with data from two new samples, one comprising drilling

Derivation of Path Independent Coupled Mix Mode Cohesive Laws from Fracture Resistance Curves

DEFF Research Database (Denmark)

Goutianos, Stergios

2016-01-01

A generalised approach is presented to derive coupled mixed mode cohesive laws described with physical parameters such as peak traction, critical opening, fracture energy and cohesive shape. The approach is based on deriving mix mode fracture resistance curves from an effective mix mode cohesive...... law at different mode mixities. From the fracture resistance curves, the normal and shear stresses of the cohesive laws can be obtained by differentiation. Since, the mixed mode cohesive laws are obtained from a fracture resistance curve (potential function), path independence is automatically...

Packing and Cohesive Properties of Some Locally Extracted Starches

African Journals Online (AJOL)

... properties of the particles affect the packing and cohesive properties of the starches, and are important in predicting the behaviour of the starches during handling and use in pharmaceutical preparations. These properties need to be closely controlled in pre-formulation studies. Keywords: Packing and cohesive properties, ...

Brownfield regeneration: Towards strengthening social cohesion?

Directory of Open Access Journals (Sweden)

Minić Marta

2016-01-01

Full Text Available In broader terms, the paper refers to the topic of brownfield regeneration, as one of the most complex mechanisms for sustainable spatial development. In addition to the fact that brownfield regeneration demands a variety of instruments, such as: tax subsidies, the change of land use ownership, soil remediation, planning regulative amendments, etc., the complexity of brownfield regeneration is primarily seen in a number of stakeholders participating in such a process. Thus, the paper focuses on the social aspect of brownfield regeneration - precisely, on researching the community role and reviewing the possibilities for achieving the 'local' interests in complex developmental processes. The main research hypothesis is that brownfield regeneration positively affects the creation of and strengthening the social cohesion in the areas close to the brownfield site. More precisley, the paper presents the ways towards strenghtening social cohesion in the initial phase of the brownfield regeneration process, as well as the effects of such a process in its operationalisation phase on social cohesion. The thesis is examined by two main parameters: 1 participation of local community, and 2 social costs and benefits of brownfield regeneration versus greenfield investment. The research results are presented in the form of argumentative essay. In fact, the critical overview of arguments for and against the main research hypothesis is provided based on the review of interdisciplinary literature in the domain of brownfield regeneration. Such research organisation ensures the identification and description of the measures needed for strengthening social cohesion, as an utmost goal of this research. The final research contribution is about offering the guidelines for similar methodological approach in urban research.

Frequent and efficient use of the sister chromatid for DNA double-strand break repair during budding yeast meiosis.

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Tamara Goldfarb

2010-10-01

Full Text Available Recombination between homologous chromosomes of different parental origin (homologs is necessary for their accurate segregation during meiosis. It has been suggested that meiotic inter-homolog recombination is promoted by a barrier to inter-sister-chromatid recombination, imposed by meiosis-specific components of the chromosome axis. Consistent with this, measures of Holliday junction-containing recombination intermediates (joint molecules [JMs] show a strong bias towards inter-homolog and against inter-sister JMs. However, recombination between sister chromatids also has an important role in meiosis. The genomes of diploid organisms in natural populations are highly polymorphic for insertions and deletions, and meiotic double-strand breaks (DSBs that form within such polymorphic regions must be repaired by inter-sister recombination. Efforts to study inter-sister recombination during meiosis, in particular to determine recombination frequencies and mechanisms, have been constrained by the inability to monitor the products of inter-sister recombination. We present here molecular-level studies of inter-sister recombination during budding yeast meiosis. We examined events initiated by DSBs in regions that lack corresponding sequences on the homolog, and show that these DSBs are efficiently repaired by inter-sister recombination. This occurs with the same timing as inter-homolog recombination, but with reduced (2- to 3-fold yields of JMs. Loss of the meiotic-chromosome-axis-associated kinase Mek1 accelerates inter-sister DSB repair and markedly increases inter-sister JM frequencies. Furthermore, inter-sister JMs formed in mek1Δ mutants are preferentially lost, while inter-homolog JMs are maintained. These findings indicate that inter-sister recombination occurs frequently during budding yeast meiosis, with the possibility that up to one-third of all recombination events occur between sister chromatids. We suggest that a Mek1-dependent reduction in

[Effects of family cohesion and adaptability on behavioral problems in preschool children].

Science.gov (United States)

Wang, Yan-Ni; Xue, Hong-Li; Chen, Qian

2016-05-01

To investigate the effects of family cohesion and adaptability on behavioral problems in preschool children. The stratified cluster multistage sampling method was used to perform a questionnaire survey in the parents of 1 284 children aged 3-6 years in the urban area of Lanzhou, China. The general status questionnaire, Conners Child Behavior Checklist (Parent Symptom Question), and Family Adaptability and Cohesion Scale, Second edition, Chinese version (FACESII-CV) were used to investigate behavioral problems and family cohesion and adaptability. The overall detection rate of behavioral problems in preschool children was 17.13%. The children with different types of family cohesion had different detection rates of behavioral problems, and those with free-type family cohesion showed the highest detection rate of behavioral problems (40.2%). The children with different types of family adaptability also had different detection rates of behavioral problems, and those with stiffness type showed the highest detection rate of behavioral problems (25.1%). The behavioral problems in preschool children were negatively correlated with family cohesion and adaptability. During the growth of preschool children, family cohesion and adaptability have certain effects on the mental development of preschool children.

Sister chromatid exchange in children of Seventh-Day Adventists and matched controls.

Science.gov (United States)

Hermansen, R; Waksvik, H; Fønnebø, V

1991-03-01

The low risk of cancer in Seventh-Day Adventists (SDAs) has been suggested to be due to genetic selection. To investigate this claim we examined the sister chromatid exchange (SCE) frequency in peripheral blood lymphocytes in 16 SDA children in Tromsø, all aged 0.5-8 years and 16 controls matched for sex and age. In 12 of 16 pairs, the SDA children had a lower SCE frequency than the controls. The mean difference was 4.06 (95% confidence interval -17.02-8.89, P = 0.51). There was no sex difference, and no correlation between age and SCE frequency. The genetic starting point with regard to SCE frequency seems to be the same for SDA children and controls.

Cohesion: An Overview for the Teacher of Reading. Revised.

Science.gov (United States)

Chapman, L. John

Pronouns, substitutes, elipses, conjunctions, synonyms, antonyms, superordinates and subordinates, and part-whole relations all provide cohesive ties that help a reader understand text. A study at Britain's Open University (England) has revealed the way in which the perception of cohesive ties is achieved as children's reading ability grows.…

Left-right symmetry breaking in mice by left-right dynein may occur via a biased chromatid segregation mechanism, without directly involving the Nodal gene

Energy Technology Data Exchange (ETDEWEB)

Sauer, Stephan; Klar, Amar J. S., E-mail: sauers@mail.nih.gov, E-mail: klara@mail.nih.gov [Gene Regulation and Chromosome Biology Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD (United States)

2012-11-16

Ever since cloning the classic iv (inversedviscerum) mutation identified the “left-right dynein” (lrd) gene in mice, most research on body laterality determination has focused on its function in motile cilia at the node embryonic organizer. This model is attractive, as it links chirality of cilia architecture to asymmetry development. However, lrd is also expressed in blastocysts and embryonic stem cells, where it was shown to bias the segregation of recombined sister chromatids away from each other in mitosis. These data suggested that lrd is part of a cellular mechanism that recognizes and selectively segregates sister chromatids based on their replication history: old “Watson” versus old “Crick” strands. We previously proposed that the mouse left-right axis is established via an asymmetric cell division prior to/or during gastrulation. In this model, left-right dynein selectively segregates epigenetically differentiated sister chromatids harboring a hypothetical “left-right axis development 1” (“lra1”) gene during the left-right axis establishing cell division. Here, asymmetry development would be ultimately governed by the chirality of the cytoskeleton and the DNA molecule. Our model predicts that randomization of chromatid segregation in lrd mutants should produce embryos with 25% situs solitus, 25% situs inversus, and 50% embryonic death due to heterotaxia and isomerism. Here we confirmed this prediction by using two distinct lrd mutant alleles. Other than lrd, thus far Nodal gene is the most upstream function implicated in visceral organs laterality determination. We next tested whether the Nodal gene constitutes the lra1 gene hypothesized in the model by testing mutant’s effect on 50% embryonic lethality observed in lrd mutants. Since Nodal mutation did not suppress lethality, we conclude that Nodal is not equivalent to the lra1 gene. In summary, we describe the origin of 50% lethality in lrd mutant mice not yet explained by any other

Left-right symmetry breaking in mice by left-right dynein may occur via a biased chromatid segregation mechanism, without directly involving the Nodal gene

International Nuclear Information System (INIS)

Sauer, Stephan; Klar, Amar J. S.

2012-01-01

Ever since cloning the classic iv (inversedviscerum) mutation identified the “left-right dynein” (lrd) gene in mice, most research on body laterality determination has focused on its function in motile cilia at the node embryonic organizer. This model is attractive, as it links chirality of cilia architecture to asymmetry development. However, lrd is also expressed in blastocysts and embryonic stem cells, where it was shown to bias the segregation of recombined sister chromatids away from each other in mitosis. These data suggested that lrd is part of a cellular mechanism that recognizes and selectively segregates sister chromatids based on their replication history: old “Watson” versus old “Crick” strands. We previously proposed that the mouse left-right axis is established via an asymmetric cell division prior to/or during gastrulation. In this model, left-right dynein selectively segregates epigenetically differentiated sister chromatids harboring a hypothetical “left-right axis development 1” (“lra1”) gene during the left-right axis establishing cell division. Here, asymmetry development would be ultimately governed by the chirality of the cytoskeleton and the DNA molecule. Our model predicts that randomization of chromatid segregation in lrd mutants should produce embryos with 25% situs solitus, 25% situs inversus, and 50% embryonic death due to heterotaxia and isomerism. Here we confirmed this prediction by using two distinct lrd mutant alleles. Other than lrd, thus far Nodal gene is the most upstream function implicated in visceral organs laterality determination. We next tested whether the Nodal gene constitutes the lra1 gene hypothesized in the model by testing mutant’s effect on 50% embryonic lethality observed in lrd mutants. Since Nodal mutation did not suppress lethality, we conclude that Nodal is not equivalent to the lra1 gene. In summary, we describe the origin of 50% lethality in lrd mutant mice not yet explained by any other

Left-right symmetry breaking in mice by left-right dynein may occur via a biased chromatid segregation mechanism, without directly involving the Nodal gene

Directory of Open Access Journals (Sweden)

Stephan eSauer

2012-11-01

Full Text Available Ever since cloning the classic iv mutation identified the ‘left-right dynein’ (lrd gene in mice, most research on body laterality determination has focused on its function in motile cilia at the node embryonic organizer. This model is attractive, as it links chirality of cilia architecture to asymmetry development. However, lrd is also expressed in blastocysts and embryonic stem cells, where it was shown to bias the segregation of recombined sister chromatids away from each other in mitosis. These data suggested that lrd is part of a cellular mechanism that recognizes and selectively segregates sister chromatids based on their replication history: old ‘Watson’ vs. old ‘Crick’ strands. We previously proposed that the mouse left-right axis is established via an asymmetric cell division prior to/or during gastrulation. In this model, left-right dynein selectively segregates epigenetically differentiated sister chromatids harboring a hypothetical ‘left-right axis development 1’ (‘lra1’ gene during the left-right axis establishing cell division. Here, asymmetry development would be ultimately governed by the chirality of the cytoskeleton and the DNA molecule. Our model predicts that randomization of chromatid segregation in lrd mutants should produce embryos with 25% situs solitus, 25% situs inversus, and 50% embryonic death due to heterotaxia and isomerism. Here we confirmed this prediction by using two distinct lrd mutant alleles. Other than lrd, thus far Nodal gene is the most upstream function implicated in visceral organs laterality determination. We next tested whether the Nodal gene constitutes the lra1 gene hypothesized in the model by testing mutant’s effect on 50% embryonic lethality observed in lrd mutants. Since Nodal mutation did not suppress lethality, we conclude that Nodal is not equivalent to the lra1 gene. In summary, we describe the origin of 50% lethality in lrd mutant mice not yet explained by any other

Effect of cohesion on local compaction and granulation of sheared soft granular materials

Directory of Open Access Journals (Sweden)

Roy Sudeshna

2017-01-01

Full Text Available This paper results from an ongoing investigation of the effect of cohesion on the compaction of sheared soft wet granular materials. We compare dry non-cohesive and wet moderately-to-strongly cohesive soft almost frictionless granular materials and report the effect of cohesion between the grains on the local volume fraction. We study this in a three dimensional, unconfined, slowly sheared split-bottom ring shear cell, where materials while sheared are subject to compression under the confining weight of the material above. Our results show that inter-particle cohesion has a considerable impact on the compaction of soft materials. Cohesion causes additional stresses, due to capillary forces between particles, leading to an increase in volume fraction due to higher compaction. This effect is not visible in a system of infinitely stiff particles. In addition, acting oppositely, we observe a general decrease in volume fraction due to increased cohesion for frictional particle, which we attribute to the role of contact friction that enhances dilation.

Sister chromatid exchange induced by X-irradiation of retinoblastoma lymphocytes

International Nuclear Information System (INIS)

Abramovsky-Kaplan, I.; Jones, I.S.

1984-01-01

Lymphocyte cultures were employed to assess the degree of spontaneous and induced chromosomal fragility in retinoblastoma. Sister chromatid exchange (SCEs) were scored in metaphases. Three unilateral, three bilateral, eleven family members and controls were studied. Retinoblastoma (RB) lymphocytes did not exhibit increased spontaneous fragility. X-irradiation (25-200 rad) did not significantly increase SCE in unilateral retinoblastoma lymphocytes when compared with controls (P greater than 0.50). However, bilaterally affected subjects and three unaffected relatives demonstrated a statistically significant increase in SCE (P less than 0.01). In conclusion, hereditary retinoblastoma lymphocytes appear more radiosensitive than sporadic retinoblastoma, perhaps, reflecting the increased second malignancies in germinal mutation retinoblastoma. In addition, the analysis of radiation-induced SCE in peripheral blood lymphocytes of RB patients and family members may provide a valuable tool increasing the accuracy of genetic counseling for this disorder. Additional studies of RB patients and families are needed to assess the relevance of this approach to genetic counseling

An examination of the relationship between athlete leadership and cohesion using social network analysis.

Science.gov (United States)

Loughead, Todd M; Fransen, Katrien; Van Puyenbroeck, Stef; Hoffmann, Matt D; De Cuyper, Bert; Vanbeselaere, Norbert; Boen, Filip

2016-11-01

Two studies investigated the structure of different athlete leadership networks and its relationship to cohesion using social network analysis. In Study 1, we examined the relationship between a general leadership quality network and task and social cohesion as measured by the Group Environment Questionnaire (GEQ). In Study 2, we investigated the leadership networks for four different athlete leadership roles (task, motivational, social and external) and their association with task and social cohesion networks. In Study 1, the results demonstrated that the general leadership quality network was positively related to task and social cohesion. The results from Study 2 indicated positive correlations between the four leadership networks and task and social cohesion networks. Further, the motivational leadership network emerged as the strongest predictor of the task cohesion network, while the social leadership network was the strongest predictor of the social cohesion network. The results complement a growing body of research indicating that athlete leadership has a positive association with cohesion.

Cohesinopathies of a feather flock together.

Directory of Open Access Journals (Sweden)

Robert V Skibbens

Full Text Available Roberts Syndrome (RBS and Cornelia de Lange Syndrome (CdLS are severe developmental maladies that present with nearly an identical suite of multi-spectrum birth defects. Not surprisingly, RBS and CdLS arise from mutations within a single pathway--here involving cohesion. Sister chromatid tethering reactions that comprise cohesion are required for high fidelity chromosome segregation, but cohesin tethers also regulate gene transcription, promote DNA repair, and impact DNA replication. Currently, RBS is thought to arise from elevated levels of apoptosis, mitotic failure, and limited progenitor cell proliferation, while CdLS is thought to arise, instead, from transcription dysregulation. Here, we review new information that implicates RBS gene mutations in altered transcription profiles. We propose that cohesin-dependent transcription dysregulation may extend to other developmental maladies; the diagnoses of which are complicated through multi-functional proteins that manifest a sliding scale of diverse and severe phenotypes. We further review evidence that cohesinopathies are more common than currently posited.

Transport and deposition of cohesive pharmaceutical powders in human airway

Directory of Open Access Journals (Sweden)

Wang Yuan

2017-01-01

Full Text Available Pharmaceutical powders used in inhalation therapy are in the size range of 1-5 microns and are usually cohesive. Understanding the cohesive behaviour of pharmaceutical powders during their transportation in human airway is significant in optimising aerosol drug delivery and targeting. In this study, the transport and deposition of cohesive pharmaceutical powders in a human airway model is simulated by a well-established numerical model which combines computational fluid dynamics (CFD and discrete element method (DEM. The van der Waals force, as the dominant cohesive force, is simulated and its influence on particle transport and deposition behaviour is discussed. It is observed that even for dilute particle flow, the local particle concentration in the oral to trachea region can be high and particle aggregation happens due to the van der Waals force of attraction. It is concluded that the deposition mechanism for cohesive pharmaceutical powders, on one hand, is dominated by particle inertial impaction, as proven by previous studies; on the other hand, is significantly affected by particle aggregation induced by van der Waals force. To maximum respiratory drug delivery efficiency, efforts should be made to avoid pharmaceutical powder aggregation in human oral-to-trachea airway.

Transport and deposition of cohesive pharmaceutical powders in human airway

Science.gov (United States)

Wang, Yuan; Chu, Kaiwei; Yu, Aibing

2017-06-01

Pharmaceutical powders used in inhalation therapy are in the size range of 1-5 microns and are usually cohesive. Understanding the cohesive behaviour of pharmaceutical powders during their transportation in human airway is significant in optimising aerosol drug delivery and targeting. In this study, the transport and deposition of cohesive pharmaceutical powders in a human airway model is simulated by a well-established numerical model which combines computational fluid dynamics (CFD) and discrete element method (DEM). The van der Waals force, as the dominant cohesive force, is simulated and its influence on particle transport and deposition behaviour is discussed. It is observed that even for dilute particle flow, the local particle concentration in the oral to trachea region can be high and particle aggregation happens due to the van der Waals force of attraction. It is concluded that the deposition mechanism for cohesive pharmaceutical powders, on one hand, is dominated by particle inertial impaction, as proven by previous studies; on the other hand, is significantly affected by particle aggregation induced by van der Waals force. To maximum respiratory drug delivery efficiency, efforts should be made to avoid pharmaceutical powder aggregation in human oral-to-trachea airway.

Relationship Among Team Collective Efficacy, Cohesion, and Coaching Competency in Sports

OpenAIRE

Manning, Clayton T.

2007-01-01

A team's performance in any sport can be predicted by many factors. Some of these factors include team collective efficacy, team cohesiveness, and coaching competency. Currently, there is little research investigating the relationships among teams' beliefs about their capabilities, their level of cohesion, and their perceptions of coaching competency on overall sport performance. The purpose of this study was to document the relationship among collective efficacy, cohesion, and coaching on sp...

Mixed Mode cohesive law with interface dilatation

DEFF Research Database (Denmark)

Sørensen, Bent F.; Goutianos, Stergios

2014-01-01

displacements. As the crack faces displace relatively to each other, the roughness asperities ride on top of each other and result in an opening (dilatation) in the normal direction. Furthermore, the interaction of the crack surfaces in the contact zone gives rise to compressive normal stresses and frictional...... shear stresses opposing the crack face displacements. A phenomenological Mixed Mode cohesive zone law, derived from a potential function, is developed to describe the above mentioned fracture behaviour under monotonic opening. The interface dilatation introduces two new lengths. The cohesive law...

Elongational rheology and cohesive fracture of photo-oxidated LDPE

Energy Technology Data Exchange (ETDEWEB)

Rolón-Garrido, Víctor H., E-mail: victor.h.rolongarrido@tu-berlin.de; Wagner, Manfred H. [Chair of Polymer Engineering/Polymer Physics, Berlin Institute of Technology (TU Berlin), Fasanenstrasse 90, D-10623 Berlin (Germany)

2014-01-15

It was found recently that low-density polyethylene (LDPE) samples with different degrees of photo-oxidation represent an interesting system to study the transition from ductile to cohesive fracture and the aspects of the cohesive rupture in elongational flow. Sheets of LDPE were subjected to photo-oxidation in the presence of air using a xenon lamp to irradiate the samples for times between 1 day and 6 weeks. Characterisation methods included Fourier transform infrared spectroscopy, solvent extraction method, and rheology in shear and uniaxial extensional flows. Linear viscoelasticity was increasingly affected by increasing photo-oxidation due to crosslinking of LDPE, as corroborated by the carbonyl index, acid and aldehydes groups, and gel fraction. The molecular stress function model was used to quantify the experimental data, and the nonlinear model parameter β was found to be correlated with the gel content. The uniaxial data showed that the transition from ductile to cohesive fracture was shifted to lower elongational rates, the higher the gel content was. From 2 weeks photo-oxidation onwards, cohesive rupture occurred at every strain rate investigated. The true strain and true stress at cohesive fracture as well as the energy density applied to the sample up to fracture were analyzed. At low gel content, rupture was mainly determined by the melt fraction while at high gel content, rupture occurred predominantly in the gel structure. The strain at break was found to be independent of strain rate, contrary to the stress at break and the energy density. Thus, the true strain and not the stress at break or the energy density was found to be the relevant physical quantity to describe cohesive fracture behavior of photo-oxidated LDPE. The equilibrium modulus of the gel structures was correlated with the true strain at rupture. The stiffer the gel structure, the lower was the deformation tolerated before the sample breaks.

Evaluating Lexical Cohesion in Nigerian Newspaper Genres: Focus on the Editorials

Directory of Open Access Journals (Sweden)

Zubairu Malah

2016-11-01

Full Text Available Applied linguists paying scholarly attention to newspaper genres have often argued that findings emerging from such studies would be of pedagogical significance because most of the newspaper genres share certain conventional features with school genres. Similarly, this study explored lexical cohesion in newspaper editorials, and it is understood that the findings could help learners in handling persuasive writings. The study sought to identify the dominant sources of lexical cohesion in the editorials, and also to examine how lexical cohesion is utilized to achieve coherence in the editorials. Drawing on Systemic Functional Linguistics (SFL, the study applied Eggins’ (2004 model of lexical cohesion and analyzed 30 editorial texts of 20, 354 words drawn from three major Nigerian newspapers: The Guardian, The Nation, and Vanguard. The analysis revealed 2, 685 ties across 849 sentences. The data demonstrated that the major types of lexical cohesion in the editorials include: repetition (49.5%, expectancy relations (15. 8%, class/sub-class (11%, and synonymy (10.8%. It was further revealed that lexical cohesion devices, which formed into chains (586 and isolated ties (837, were utilized in building coherence in the editorial texts. It was finally shown how findings of the study could be beneficial in ESP, EAP, and EGP learning, especially in persuasive writings.

Cohesion and device reliability in organic bulk heterojunction photovoltaic cells

KAUST Repository

Brand, Vitali; Bruner, Christopher; Dauskardt, Reinhold H.

2012-01-01

that the phase separated bulk heterojunction layer is the weakest layer and report quantitative cohesion values which ranged from ∼1 to 20 J m -2. The effects of layer thickness, composition, and annealing treatments on layer cohesion are investigated. Using

Differences by Sexual Orientation in Perceptions of Neighborhood Cohesion: Implications for Health.

Science.gov (United States)

Henning-Smith, Carrie; Gonzales, Gilbert

2018-06-01

A large body of research documents the relationship between health and place, including the positive association between neighborhood cohesion and health. However, very little research has examined neighborhood cohesion by sexual orientation. This paper addresses that gap by examining differences in perceived neighborhood cohesion by sexual orientation. We use data from the 2016 National Health Interview Survey (n = 28,164 respondents aged 18 years and older) to examine bivariate differences by sexual orientation in four measures of neighborhood cohesion. We then use ordered logistic regression models to assess the relationship between sexual orientation and a scaled measure of neighborhood cohesion, adjusting for socio-demographic characteristics, living arrangements, health status, region, and neighborhood tenure. We find that lesbian, gay, and bisexual (LGB) adults are less likely to say that they live in a close-knit neighborhood (54.6 vs. 65.6%, p < 0.001), they can count on their neighbors (74.7 vs. 83.1%, p < 0.001), they trust their neighbors (75.5 vs. 83.7%, p < 0.001), or people in their neighborhood help each other out (72.9 vs. 83.1%, p < 0.001), compared to heterosexual adults. Even after controlling for socio-demographic factors, neighborhood cohesion scores are lower for LGB adults compared to heterosexual adults (odds ratio of better perceived neighborhood cohesion for sexual minorities: 0.70, p < 0.001). Overall, LGB adults report worse neighborhood cohesion across multiple measures, even after adjusting for individual characteristics and neighborhood tenure. Because living in a cohesive neighborhood is associated with better health outcomes, future research, community-level initiatives, and public policy efforts should focus on creating welcoming neighborhood environments for sexual minorities.

Differences in neighborhood social cohesion and aerobic physical activity by Latino subgroup

Directory of Open Access Journals (Sweden)

Rosenda Murillo

2016-12-01

Full Text Available Previous research has examined the role of neighborhood social cohesion in physical activity outcomes; however, less is known about this relationship across Latino subgroups. The purpose of our study was to examine the association between neighborhood social cohesion and aerobic leisure-time physical activity (LTPA among Latino adults and to determine whether these associations differ by Latino subgroup. We used cross-sectional 2013–2014 National Health Interview Survey (NHIS data on Latinos originating from 5 countries/regions (i.e., Latinos of Puerto Rican, Mexican/Mexican-American, Cuban/Cuban-American, Dominican and Central or South American origin aged ≥18 years (n=11,126. Multivariable logistic regression models were used to estimate associations between self-reported neighborhood social cohesion and meeting aerobic LTPA guidelines. Models were adjusted for age, sex, education, and acculturation. We also investigated whether associations varied by Latino subgroup. In adjusted models for all Latino adults, compared with those reporting low social cohesion, individuals who reported high social cohesion (Odds Ratio [OR]: 1.33; 95% Confidence Interval [CI]: 1.17–1.52 were significantly more likely to meet the aerobic physical activity guideline. When stratified by Latino subgroups, among Mexican/Mexicans-Americans (OR: 1.39; 95% CI: 1.16, 1.66 and Cuban/Cuban Americans (OR: 1.73; 95% CI: 1.00, 2.97 high social cohesion was associated with meeting the aerobic activity guideline. Among Dominicans, those who reported medium social cohesion (OR: 0.52, 95% CI: 0.29, 0.93 were less likely to meet the aerobic activity guideline. When examining aerobic physical activity outcomes in the Latino population, the role of neighborhood social cohesion and the variability among Latino subgroups should be considered. Keywords: Neighborhood social cohesion, Physical activity, Latinos, subgroups

The role of SEA in integrating and balancing high policy objectives in European cohesion funding programmes

International Nuclear Information System (INIS)

Jiricka, Alexandra; Pröbstl, Ulrike

2013-01-01

Funding programmes for European cohesion policy are a crucial tool to support the sustainability goals of the European Union and national policies of its member states. All these funding programmes require a Strategic Environmental Assessment (SEA) to enhance sustainable development. This article compares five first SEA applications at cohesion policy level to discuss challenges, limitations and benefits of this instrument. In order to support the SEA-process a “Handbook on SEA for Cohesion Policy 2007–13” (GRDP 2006) was developed. The paper examines the special requirements and challenges at the programme level given the special conditions for stakeholder involvement, integration of SEA in the programme development process and strategies to cope with uncertainties to ensure real compatibility with policy goals. Using action research and in-depth interviews with SEA planners and programme managers enabled us to analyse the suitability of the methodology proposed by the handbook. The results show that some recommendations of the handbook should be changed in order to increase the transparency and to enhance the standard and comparability of the SEA-documents. Overall the SEA proved to be a rather successful tool for the integration of sustainability goals at the EU and national policy levels. Its particular strengths emerged as the process makes uncertainties visible and leads to possible redefinitions while maintaining actual policy goals. - Highlights: ► Comparing five case studies of first applications of SEA at cohesion policy level. ► Overall the SEA proved to be a rather successful tool for the integration of sustainability goals. ► The study makes uncertainties visible and shows how SEA could lead to possible redefinitions.

Authentic leadership, group cohesion and group identification in security and emergency teams.

Science.gov (United States)

García-Guiu López, Carlos; Molero Alonso, Fernando; Moya Morales, Miguel; Moriano León, Juan Antonio

2015-01-01

Authentic leadership (AL) is a kind of leadership that inspires and promotes positive psychological capacities, underlining the moral and ethical component of behavior. The proposed investigation studies the relations among AL, cohesion, and group identification in security and emergency teams. A cross-sectional research design was conducted in which participated 221 members from 26 fire departments and operative teams from the local police of three Spanish provinces. The following questionnaires were administered: Authentic Leadership (ALQ), Group Cohesion (GEQ), and Mael and Ashford's Group Identification Questionnaire. A direct and positive relation was found between AL, cohesion, and group identification. An indirect relation was also found between AL and group cohesion through group identification, indicating the existence of partial mediation. The utility of the proposed model based on AL is considered; this model can be employed by those in charge of the fire departments and operative groups in organizations to improve workteams' cohesion. Both AL and group identification help to explain group cohesion in organizations committed to security and emergencies.

Elevated sister chromatid exchange frequencies in New Zealand Vietnam War veterans.

Science.gov (United States)

Rowland, R E; Edwards, L A; Podd, J V

2007-01-01

From July 1965 until November 1971, New Zealand Defence Force Personnel fought in the Vietnam War. During this time more than 76,500,000 litres of phenoxylic herbicides were sprayed over parts of Southern Vietnam and Laos, the most common being known as 'Agent Orange'. The current study aimed to ascertain whether or not New Zealand Vietnam War veterans show evidence of genetic disturbance arising as a consequence of their now confirmed exposure to these defoliants. A sample group of 24 New Zealand Vietnam War veterans and 23 control volunteers were compared using an SCE (sister chromatid exchange) analysis. The results from the SCE study show a highly significant difference (P Vietnam War veterans studied here were exposed to a clastogenic substance(s) which continues to exert an observable genetic effect today, and suggest that this is attributable to their service in Vietnam. Copyright 2007 S. Karger AG, Basel.

Cohesion and device reliability in organic bulk heterojunction photovoltaic cells

KAUST Repository

Brand, Vitali

2012-04-01

The fracture resistance of P3HT:PC 60BM-based photovoltaic devices are characterized using quantitative adhesion and cohesion metrologies that allow identification of the weakest layer or interface in the device structure. We demonstrate that the phase separated bulk heterojunction layer is the weakest layer and report quantitative cohesion values which ranged from ∼1 to 20 J m -2. The effects of layer thickness, composition, and annealing treatments on layer cohesion are investigated. Using depth profiling and X-ray photoelectron spectroscopy on the resulting fracture surfaces, we examine the gradient of molecular components through the thickness of the bulk heterojunction layer. Finally, using atomic force microscopy we show how the topography of the failure path is related to buckling of the metal electrode and how it develops with annealing. The research provides new insights on how the molecular design, structure and composition affect the cohesive properties of organic photovoltaics. © 2011 Elsevier B.V. All rights reserved.

The territorial approach to EU cohesion policy: Current issues and evidence from Greece

Directory of Open Access Journals (Sweden)

Thoidou Elisavet

2011-01-01

Full Text Available The importance attributed to the territorial dimension of the European Union cohesion policy steadily influences its successive reforms and adaptations, while in recent years there has been an evolution in the way this particular dimension of cohesion policy is perceived. Important evidence for this is the way in which the Community Strategic Guidelines on cohesion 2007-13 take account of the territorial dimension of cohesion policy. This paper discusses the territorial approach to cohesion policy in relation to both policy and practice. Specifically, it examines the territorial dimension of regional development planning in Greece as it has emerged in the relevant official documents, namely the successive three Community Support Frameworks since 1989 and the National Strategic Reference Framework for the current 2007-13 period. The territorial dimension of the organization of the planning system is also considered in an effort to understand limitations and prospects, in light of the importance of the territorial approach to cohesion policy post-2013.

Group cohesion and starting status in successful and less successful elite volleyball teams.

Science.gov (United States)

Spink, K S

1992-08-01

The main purpose of this study was to examine the relationship between members' perceptions of group cohesion and starting status in elite volleyball teams. The results of the study revealed that the form of the cohesion-starting status relationship was moderated by the variable of success. The results for less successful teams revealed that differences did emerge between specific measures of cohesion endorsed by starters and non-starters. No such differences in cohesion emerged when the starters and non-starters on successful teams were compared. These results provide initial support for the suggestion that the most successful teams are the ones where the perceptions of cohesiveness by starters and non-starters are similar. A secondary purpose of the study was to determine whether those teams that were the most successful and similar in their members' perceptions of cohesiveness, were also the teams whose members have the most positive outcome expectancy. The results supported this prediction.

Effects of interface roughness on cohesive strength of self-assembled monolayers

Energy Technology Data Exchange (ETDEWEB)

Zhang, Chen [Department of Aerospace Engineering, University of Illinois at Urbana-Champaign, IL 61801 (United States); Awasthi, Amnaya P. [Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, 32611 (United States); Geubelle, Philippe H., E-mail: geubelle@illinois.edu [Department of Aerospace Engineering, University of Illinois at Urbana-Champaign, IL 61801 (United States); Grady, Martha E.; Sottos, Nancy R. [Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, IL 61801 (United States)

2017-03-01

Highlights: • Self-assembled monolayer/transfer-printed gold interface modeled using continuum-level simulation. • Initial deformed film profile analyzed and instability assessed. • Effective cohesive response of SAM-enhanced interface extracted from spallation model. • Reduction of up to 70% cohesive strength of the interface from incorporation of roughness demonstrated. - Abstract: Self-assembled monolayers (SAMs) are aggregates of small molecular chains that have the property to form highly ordered assemblies. The choice of terminal groups on the chains makes them excellent contenders of molecular-level tailoring. Molecular dynamics (MD) simulations and experimental observations of spallation of two SAM-enhanced gold-film/silicon-substrate interfaces have shown that the cohesive strength of SAM-enriched transfer-printed interfaces is strongly dependent on the choice of terminal groups. Though the MD results of perfectly ordered atomistic surfaces show the same qualitative trend as the experiments, they over-predict the interfacial cohesive strengths by a factor of about 50. Results from AFM studies have revealed that the roughness of these interfaces is of the same order (∼1 nm) as the range of atomistic interactions. Hence, surface roughness is a key contributor in significantly reducing interfacial cohesive strength in these systems. In this manuscript, a continuum-level study is performed to investigate the influence of surface roughness on the cohesive strength of the interface between a Si/SAM substrate and a transfer-printed gold film. We approximate the film as a deformable continuum interacting with a rough substrate of SAMs represented by a harmonic function. Using a cohesive law derived from MD, spallation is simulated to evaluate the effective traction-separation characteristics for the rough SAM–gold interface. Our analysis shows that incorporating roughness may reduce the interfacial cohesive strength by an order of magnitude depending

Flocculation Dynamics of cohesive sediment

NARCIS (Netherlands)

Maggi, F.

2005-01-01

Cohesive sediment suspended in natural waters is subject not only to transport and deposition processes but also to reactions of flocculation, \\textit{i.e.} aggregation of fine particles, and breakup of aggregates. Although aggregation and breakup occur at small and very small length scales compared

Interactive Effects of Team Cohesion on Perceived Efficacy in Semi-Professional Sport

OpenAIRE

Marcos, Francisco Miguel Leo; Miguel, Pedro Antonio Sánchez; Oliva, David Sánchez; Calvo, Tomás García

2010-01-01

The present study examined the relationships among cohesion, self-efficacy, coaches’ perceptions of their players’ efficacy at the individual level and athletes’ perceptions of their teammates’ efficacy. Participants (n = 76) recruited from four semi- professional soccer and basketball teams completed cohesiveness and efficacy questionnaires who. Data were analyzed through a correlational methodology. Results indicated significant correlations between self-efficacy and task cohesion and socia...

Characterizing delamination of fibre composites by mixed mode cohesive laws

DEFF Research Database (Denmark)

Sørensen, Bent F.; Jacobsen, Torben K.

2009-01-01

A novel method is used for the determination of mixed mode cohesive laws and bridging laws for the characterisation of crack bridging in composites. The approach is based on an application of the J integral. The obtained cohesive laws were found to possess high peak stress values. Mixed mode...

Use of a ring chromosome and pulsed-field gels to study interhomolog recombination, double-strand DNA breaks and sister-chromatid exchange in yeast

International Nuclear Information System (INIS)

Game, J.C.; Sitney, K.C.; Cook, V.E.; Mortimer, R.K.

1989-01-01

The authors describe a system that uses pulsed-field gels for the physical detection of recombinant DNA molecules, double-strand DNA breaks (DSB) and sister-chromatid exchange in the yeast Saccharomyces cerevisiae. The system makes use of a circular variant of chromosome II (Chr. III). Meiotic recombination between this ring chromosome and a linear homolog produces new molecules of sizes distinguishable on gels from either parental molecule. They demonstrate that these recombinant molecules are not present either in strains with two linear Chr. III molecules or in rad50 mutants, which are defective in meiotic recombination. In conjunction with the molecular endpoints. They present data on the timing of commitment to meiotic recombination scored genetically. They have used x-rays to linearize circular Chr. III, both to develop a sensitive method for measuring frequency of DSB and as a means of detecting double-size circles originating in part from sister-chromatid exchange, which they find to be frequent during meiosis

Cohesion in a Multinational Coalition Center

National Research Council Canada - National Science Library

Schaab, Brooke

2007-01-01

.... All of the remaining nine items fell within the agree-to-strongly agree area. On interpersonal cohesion, highest agreement was found on items addressing the importance of liking and socializing with team members...

Mind the gap! Automated concept map feedback supports students in writing cohesive explanations.

Science.gov (United States)

Lachner, Andreas; Burkhart, Christian; Nückles, Matthias

2017-03-01

Many students are challenged with the demand of writing cohesive explanations. To support students in writing cohesive explanations, we developed a computer-based feedback tool that visualizes cohesion deficits of students' explanations in a concept map. We conducted three studies to investigate the effectiveness of such feedback as well as the underlying cognitive processes. In Study 1, we found that the concept map helped students identify potential cohesion gaps in their drafts and plan remedial revisions. In Study 2, students with concept map feedback conducted revisions that resulted in more locally and globally cohesive, and also more comprehensible, explanations than the explanations of students who revised without concept map feedback. In Study 3, we replicated the findings of Study 2 by and large. More importantly, students who had received concept map feedback on a training explanation 1 week later wrote a transfer explanation without feedback that was more cohesive than the explanation of students who had received no feedback on their training explanation. The automated concept map feedback appears to particularly support the evaluation phase of the revision process. Furthermore, the feedback enabled novice writers to acquire sustainable skills in writing cohesive explanations. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Relationship between the cohesion of guest particles on the flow behaviour of interactive mixtures.

Science.gov (United States)

Mangal, Sharad; Gengenbach, Thomas; Millington-Smith, Doug; Armstrong, Brian; Morton, David A V; Larson, Ian

2016-05-01

In this study, we aimed to investigate the effects cohesion of small surface-engineered guest binder particles on the flow behaviour of interactive mixtures. Polyvinylpyrrolidone (PVP) - a model pharmaceutical binder - was spray-dried with varying l-leucine feed concentrations to create small surface-engineered binder particles with varying cohesion. These spray-dried formulations were characterised by their particle size distribution, morphology and cohesion. Interactive mixtures were produced by blending these spray-dried formulations with paracetamol. The resultant blends were visualised under scanning electron microscope to confirm formation of interactive mixtures. Surface coverage of paracetamol by guest particles as well as the flow behaviour of these mixtures were examined. The flow performance of interactive mixtures was evaluated using measurements of conditioned bulk density, basic flowability energy, aeration energy and compressibility. With higher feed l-leucine concentrations, the surface roughness of small binder particles increased, while their cohesion decreased. Visual inspection of the SEM images of the blends indicated that the guest particles adhered to the surface of paracetamol resulting in effective formation of interactive mixtures. These images also showed that the low-cohesion guest particles were better de-agglomerated that consequently formed a more homogeneous interactive mixture with paracetamol compared with high-cohesion formulations. The flow performance of interactive mixtures changed as a function of the cohesion of the guest particles. Interactive mixtures with low-cohesion guest binder particles showed notably improved bulk flow performance compared with those containing high-cohesion guest binder particles. Thus, our study suggests that the cohesion of guest particles dictates the flow performance of interactive mixtures. Crown Copyright © 2016. Published by Elsevier B.V. All rights reserved.

Social cohesion and social capital: Possible implications for the common good

Directory of Open Access Journals (Sweden)

Anita Cloete

2014-08-01

Full Text Available The main objective of the article is to identify the possible implications of social cohesion and social capital for the common good. In order to reach this overarching aim the following structure will be utilised. The first part explores the conceptual understanding of socialcohesion and social capital in order to establish how these concepts are related and how they could possibly inform each other. The contextual nature of social cohesion and social capital is briefly reflected upon, with specific reference to the South African context. The contribution of religious capital in the formation of social capital is explored in the last section of the article. The article could be viewed as mainly conceptual and explorative in nature in order to draw some conclusions about the common good of social capital and social cohesion.Intradisciplinary and/or interdisciplinary implications: This article contributes to the interdisciplinary discourse on social cohesion with specific reference to the role of congregations. It provides a critical reflection on the role of congregations with regard to bonding and bridging social capital. The contextual nature of social cohesion is also addressed with specific reference to South Africa.

The Role of Cohesive Particle Interactions on Solids Uniformity and Mobilization During Jet Mixing: Testing Recommendations

Energy Technology Data Exchange (ETDEWEB)

Gauglitz, Phillip A.; Wells, Beric E.; Bamberger, Judith A.; Fort, James A.; Chun, Jaehun; Jenks, Jeromy WJ

2010-04-01

Radioactive waste that is currently stored in large underground tanks at the Hanford Site will be staged in selected double-shell tanks (DSTs) and then transferred to the Waste Treatment and Immobilization Plant (WTP). Before being transferred, the waste will be mixed, sampled, and characterized to determine if the waste composition and meets the waste feed specifications. Washington River Protection Solutions is conducting a Tank Mixing and Sampling Demonstration Program to determine the mixing effectiveness of the current baseline mixing system that uses two jet mixer pumps and the adequacy of the planned sampling method. The overall purpose of the demonstration program is to mitigate the technical risk associated with the mixing and sampling systems meeting the feed certification requirements for transferring waste to the WTP.The purpose of this report is to analyze existing data and evaluate whether scaled mixing tests with cohesive simulants are needed to meet the overall objectives of the small-scale mixing demonstration program. This evaluation will focus on estimating the role of cohesive particle interactions on various physical phenomena that occur in parts of the mixing process. A specific focus of the evaluation will be on the uniformity of suspended solids in the mixed region. Based on the evaluation presented in this report and the absence of definitive studies, the recommendation is to conduct scaled mixing tests with cohesive particles and augment the initial testing with non-cohesive particles. In addition, planning for the quantitative tests would benefit from having test results from some scoping experiments that would provide results on the general behavior when cohesive inter-particle forces are important.

In vitro and occupational induction of sister-chromatid exchanges in human lymphocytes with furfuryl alcohol and furfural

Energy Technology Data Exchange (ETDEWEB)

Gomez-Arroyo, S.; Souza, V.

1985-06-01

Sister-chromatid exchanges (SCEs) in human lymphocytes were studied using the FPG technique in order to determine the cytogenetic effect of furfural and furfuryl alcohol. The induction of SCEs was also investigated in workers occupationally exposed to these solvents that are commonly used in the manufacture of furoic resins. The results obtained from the in vitro treatments show that furfural increased the number of SCEs, while furfuryl alcohol did not. In exposed workers, neither of these solvents increased the spontaneous frequency of SCEs per metaphase.

Homologous recombination, sister chromatid cohesion, and chromosome condensation in mammalian meiosis

NARCIS (Netherlands)

Eijpe, M.

2002-01-01

In the life cycle of sexually reproducing eukaryotes, haploid and diploid generations of cells alternate. Two types of cell division occur in such a life cycle: mitosis and meiosis. They are compared in chapter 1 . Haploid and

Perceived Social Cohesion, Frequency of Going Out, and Depressive Symptoms in Older Adults

Directory of Open Access Journals (Sweden)

Namkee G. Choi PhD

2015-11-01

Full Text Available Objective: To examine both cross-sectional and longitudinal relationships between older adults’ perceptions of social cohesion in their community and depressive symptoms and the potential mediating effect of the frequency of going outside one’s home/building. Method: Using two waves (T1 and T2 of the National Health and Aging Trend Study ( n = 5,326, gender-stratified structural equation models were estimated to determine direct and indirect effects of perceived social cohesion on depressive symptoms. Results: At T1, both perceived cohesion and frequency of going out were directly associated with depressive symptoms; however, perceived cohesion predicted frequency of going out only for women. At T2, only frequency of going out was directly associated with depressive symptoms, although perceived cohesion predicted frequency of going out for both genders. T1 perceived cohesion did not predict T2 depressive symptoms. T1 depressive symptoms were the strongest predictor of T2 depressive symptoms. Conclusion: The findings underscore the importance of enhancing the social environment in promoting mental health in late life through active aging.

Structural quality of polyacrylamide-treated cohesive soils in the coastal tablelands of Pernambuco

Directory of Open Access Journals (Sweden)

Diego Vandeval Maranhão de Melo

2014-04-01

Full Text Available Water-soluble polymers are characterized as effective flocculating agents due to their molecular features. Their application to soils with horizons with structural problems, e.g, a cohesive character, contributes to improvements in the physical quality and thus to the agricultural suitability of such soils. The purpose of this study was to evaluate the structural quality of soils with cohesive horizons of coastal tablelands in the State of Pernambuco treated with polyacrylamide (PAM as chemical soil conditioner. To this end, three horizons (one cohesive and two non-cohesive of a Yellow Argisol (Ultisol were evaluated and to compare cohesive horizons, the horizon of a Yellow Latosol (Oxisol was selected. The treatments consisted of aqueous PAM solutions (12.5; 50.0; 100.0 mg kg-1 and distilled water (control. The structural aspects of the horizons were evaluated by the stability (soil mass retained in five diameter classes, aggregate distribution per size class (mean weight diameter- MWD, geometric mean diameter - GMD and the magnitude of the changes introduced by PAM by measuring the sensitivity index (Si. Aqueous PAM solutions increased aggregate stability in the largest evaluated diameter class of the cohesive and non-cohesive horizons, resulting in higher MWD and GMD, with highest efficiency of the 100 mg kg-1 solution. The cohesive horizon Bt1 in the Ultisol was most sensitive to the action of PAM, where highest Si values were found, but the structural quality of the BA horizon of the Oxisol was better in terms of stability and aggregate size distribution.

Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres.

Science.gov (United States)

Ahonen, Leena J; Kukkonen, Anu M; Pouwels, Jeroen; Bolton, Margaret A; Jingle, Christopher D; Stukenberg, P Todd; Kallio, Marko J

2009-02-01

Incenp is an essential mitotic protein that, together with Aurora B, Survivin, and Borealin, forms the core of the chromosomal passenger protein complex (CPC). The CPC regulates various mitotic processes and functions to maintain genomic stability. The proper subcellular localization of the CPC and its full catalytic activity require the presence of each core subunit in the complex. We have investigated the mitotic tasks of the CPC using a function blocking antibody against Incenp microinjected into cells at different mitotic phases. This method allowed temporal analysis of CPC functions without perturbation of complex assembly or activity prior to injection. We have also studied the dynamic properties of Incenp and Aurora B using fusion protein photobleaching. We found that in early mitotic cells, Incenp and Aurora B exhibit dynamic turnover at centromeres, which is prevented by the anti-Incenp antibody. In these cells, the loss of centromeric CPC turnover is accompanied by forced mitotic exit without the execution of cytokinesis. Introduction of anti-Incenp antibody into early anaphase cells causes abnormalities in sister chromatid separation through defects in anaphase spindle functions. In summary, our data uncovers new mitotic roles for the CPC in anaphase and proposes that CPC turnover at centromeres modulates spindle assembly checkpoint signaling.

Proteomic analysis of human metaphase chromosomes reveals Topoisomerase II alpha as an Aurora B substrate

DEFF Research Database (Denmark)

Morrison, Ciaran; Henzing, Alexander J; Jensen, Ole Nørregaard

2002-01-01

B in the presence of radioactive ATP. Immunoblot analysis confirmed the HeLa scaffold fraction to be enriched for known chromosomal proteins including CENP-A, CENP-B, CENP-C, ScII and INCENP. Mass spectrometry of bands excised from one-dimensional polyacrylamide gels further defined the protein......The essential Aurora B kinase is a chromosomal passenger protein that is required for mitotic chromosome alignment and segregation. Aurora B function is dependent on the chromosome passenger, INCENP. INCENP, in turn, requires sister chromatid cohesion for its appropriate behaviour. Relatively few...... composition of the extracted chromosome fraction. Cloning, fluorescent tagging and expression in HeLa cells of the putative GTP-binding protein NGB/CRFG demonstrated it to be a novel mitotic chromosome protein, with a perichromosomal localisation. Identi fication of the protein bands corresponding to those...

Evaluation of the persistence in the induction of Sister Chromatid Exchanges (SCE) by alkylating agents

International Nuclear Information System (INIS)

Rodriguez R, R.; Huerta V, C.; MOrales R, P.R.

2006-01-01

The persistence in the induction of sister chromatid exchanges (SCE) by the alkylating agents methyl and ethyl-methanesulfonates (MMS and EMS) was evaluated. For it, to groups of mice its were administered a dose of these agents and later its were analyzed the induced SCE's in two periods: early and late. Both agents caused high increments of SCE in the early period and small in the late one; however, the caused lately by EMS was significantly bigger. This late induction of SCE by EMS possibly is associated with an epigenetic change or with the presence of etiladucts in the phosphodiester bonds of the DNA. (Author)

Influence of Sport Education on Group Cohesion in University Physical Education

Science.gov (United States)

Jenkins, Jayne M.; Alderman, Brandon L.

2011-01-01

The Sport Education ("SE") curricular model incorporated within university physical education Basic Instruction Program (BIP) may increase group cohesion. This study's purpose was to identify student perceptions of a BIP course taught within "SE," and investigate group cohesion in differing activity content. Participants…

Family cohesion, acculturation, maternal cortisol, and preterm birth in Mexican-American women

Directory of Open Access Journals (Sweden)

Ruiz RJ

2013-05-01

Full Text Available R Jeanne Ruiz,1 Rita H Pickler,2 C Nathan Marti,3 Nancy Jallo41College of Nursing, The Ohio State University, Columbus, OH, USA; 2Department of Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; 3Abacist Analytics, Austin, TX, USA; 4School of Nursing, Virginia Commonwealth University, Richmond, VA, USAObjective: To examine the potential moderating effects of family cohesion and acculturation on the physiological stress response (cortisol as a predictor of preterm birth (PTB in pregnant Mexican-American women.Methods: The sample included 470 participants; 33 had preterm births. All participants were self-identified as Mexican-American. In this cross-sectional study, family cohesion was measured by a self-report questionnaire. Acculturation was measured by self-report questionnaire as well as by years in the United States and country of birth. Stress was measured by serum cortisol. All measures were obtained at 22—24 weeks gestation. Additional data including history of PTB were obtained from the health record. Data analysis was primarily conducted using logistic regression.Results: The relationship between stress and PTB was predicted by family cohesion (estimate/standard error [E/SE] = —2.46, P = 0.014 and acculturation (E/SE = 2.56, P = 0.011. In addition, there was an interaction between family cohesion and history of previous PTB (E/SE = —2.12, P = 0.035.Conclusion: Results indicate that the impact of cortisol on PTB is predicted by acculturation and family cohesion such that higher levels of cortisol in conjunction with higher levels of acculturation and lower levels of family cohesion are associated with increased risk of PTB. In addition, low family cohesion in combination with a history of PTB was associated with higher levels of PTB. Assessment of family cohesion, including problem solving, adherence to family decisions, family shared space, and activity, should be included as part of prenatal

Development of low energy electron beam irradiation technology. Application to cohesive and adhesive agents

International Nuclear Information System (INIS)

Ito, Hisashi; Enomoto, Ichiro; Tsuchiya, Mitsuaki

1996-01-01

The hightening of the cohesive and adhesive performances of rubber cohesive and adhesive agents, of which the main component is electron beam-cross-linked styrene-isoprene block copolymer (SIS), was tried. Cohesive and adhesive agents are cohesive agents at the time of use, but change to adhesive property by the lapse of time or the means using heat, light or radiation, and further, partially to separating property. This time, as a cohesion-giving agent, ARKON P-100 system was examined, and the heightening of adhesive performance including the improvement of the heat resistance and solvent endurance, which are the demerits of rubber, was investigated. Also the difference of the cohesive and adhesive performances due to the kinds of cohesion-giving agents was examined. The samples were prepared by irradiating the films on which the SIS was applied. The measurement of gel proportion, the holding force test at elevated temperature, the measurement of DSC and 180deg separation test were carried out. Respective testing methods and the results are reported. By electron beam irradiation, the heat resistance and solvent endurance were improved without affecting the separation force. (K.I.)

Sister chromatid exchanges and micronuclei analysis in lymphocytes of men exposed to simazine through drinking water.

Science.gov (United States)

Suárez, Susanna; Rubio, Arantxa; Sueiro, Rosa Ana; Garrido, Joaquín

2003-06-06

In some cities of the autonomous community of Extremadura (south-west of Spain), levels of simazine from 10 to 30 ppm were detected in tap water. To analyse the possible effect of this herbicide, two biomarkers, sister chromatid exchanges (SCE) and micronuclei (MN), were used in peripheral blood lymphocytes from males exposed to simazine through drinking water. SCE and MN analysis failed to detect any statistically significant increase in the people exposed to simazine when compared with the controls. With respect to high frequency cells (HFC), a statistically significant difference was detected between exposed and control groups.

Group cohesion in foraging meerkats: follow the moving 'vocal hot spot'.

Science.gov (United States)

Gall, Gabriella E C; Manser, Marta B

2017-04-01

Group coordination, when 'on the move' or when visibility is low, is a challenge faced by many social living animals. While some animals manage to maintain cohesion solely through visual contact, the mechanism of group cohesion through other modes of communication, a necessity when visual contact is reduced, is not yet understood. Meerkats ( Suricata suricatta ), a small, social carnivore, forage as a cohesive group while moving continuously. While foraging, they frequently emit 'close calls', soft close-range contact calls. Variations in their call rates based on their local environment, coupled with individual movement, produce a dynamic acoustic landscape with a moving 'vocal hotspot' of the highest calling activity. We investigated whether meerkats follow such a vocal hotspot by playing back close calls of multiple individuals to foraging meerkats from the front and back edge of the group simultaneously. These two artificially induced vocal hotspots caused the group to spatially elongate and split into two subgroups. We conclude that meerkats use the emergent dynamic call pattern of the group to adjust their movement direction and maintain cohesion. Our study describes a highly flexible mechanism for the maintenance of group cohesion through vocal communication, for mobile species in habitats with low visibility and where movement decisions need to be adjusted continuously to changing environmental conditions.

Analysis of cohesion and collective efficacy profiles for the performance of soccer players.

Science.gov (United States)

Leo, Francisco M; Sánchez-Miguel, Pedro A; Sánchez-Oliva, David; Amado, Diana; García-Calvo, Tomás

2013-12-18

The principal aims of the study were to define different profiles of cohesion and perceived efficacy in soccer players and to measure their differences in performance. The subjects were 235 soccer players in the under-18 category who played in the National League in Spain and 15 coaches whose ages ranged from 29 to 45 years. Diverse instruments to assess cohesion, perceived efficacy, and expectations of success were used in the study. Moreover, we measured playing time and performance. The results of the study proved the existence of four cohesion and efficacy profiles that presented significant differences in expectations of success, playing time, and performance. Furthermore, significant differences were found in the distribution of players in the teams as a function of performance. The main conclusion of this study is that soccer players with higher cohesion and collective efficacy levels belonged to teams that completed the season at the top-level classification. In contrast, athletes with low cohesion and collective efficacy usually played in unsuccessful teams. Coaches and sports psychologists are encouraged to promote both social and task cohesion and collective efficacy to enhance team performance.

Mode I Cohesive Law Characterization of Through-Crack Propagation in a Multidirectional Laminate

Science.gov (United States)

Bergan, Andrew C.; Davila, Carlos G.; Leone, Frank A.; Awerbuch, Jonathan; Tan, Tein-Min

2014-01-01

A method is proposed and assessed for the experimental characterization of through-the-thickness crack propagation in multidirectional composite laminates with a cohesive law. The fracture toughness and crack opening displacement are measured and used to determine a cohesive law. Two methods of computing fracture toughness are assessed and compared. While previously proposed cohesive characterizations based on the R-curve exhibit size effects, the proposed approach results in a cohesive law that is a material property. The compact tension specimen configuration is used to propagate damage while load and full-field displacements are recorded. These measurements are used to compute the fracture toughness and crack opening displacement from which the cohesive law is characterized. The experimental results show that a steady-state fracture toughness is not reached. However, the proposed method extrapolates to steady-state and is demonstrated capable of predicting the structural behavior of geometrically-scaled specimens.

Cohesive zone modeling of intergranular cracking in polycrystalline aggregates

International Nuclear Information System (INIS)

Simonovski, Igor; Cizelj, Leon

2015-01-01

Highlights: • Alternative approach to cohesive elements is proposed: cohesive-zone contact. • Applicability to measured and simulated grain structures is demonstrated. • Normal and normal/shear separation as a damage initialization is explored. • Normal/shear damage initialization significantly reduces ductility. • Little difference in Voronoi aggregate size on macroscopic response. - Abstract: Understanding and controlling early damage initiation and evolution are amongst the most important challenges in nuclear power plants, occurring in ferritic, austenitic steels and nickel based alloys. In this work a meso-scale approach to modeling initiation and evolution of early intergranular cracking is presented. This damage mechanism is present in a number of nuclear power plant components and depends on the material (e.g. composition, heat treatment, microstructure), environment and load. Finite element modeling is used to explicitly model the microstructure – both the grains and the grain boundaries. Spatial Voronoi tessellation is used to obtain the grain topology. In addition, measured topology of a 0.4 mm stainless steel wire is used. Anisotropic elasticity and crystal plasticity are used as constitutive laws for the grains. Grain boundaries are modeled using the cohesive zone approach. Different modeling assumptions/parameters are evaluated against the numerical stability criteria. The biggest positive contribution to numerical stability is the use of cohesive-type contact instead of cohesive elements. A small amount of viscous regularization should be also used along with the addition of a small amount of viscous forces to the global equilibrium equations. Two cases of grain boundary damage initiation are explored: (1) initiation due to normal separation and (2) initiation due to a combination of normal and shear separation. The second criterion significantly decreases the ductility of an aggregate and slightly improves the numerical stability

Interrelations between Energy Security Economics and Social Cohesion: Analysis of a Lithuanian Case

Directory of Open Access Journals (Sweden)

Dainius Genys

2015-12-01

Full Text Available Growing attention to sustainable development in academic discourse fosters discussions on how energy security affects society. In most cases the discussions consider the political and economic consequences, which affect or may affect the society. The aim of the article is to assess the impact of energy security economics on social cohesion in Lithuania. To achieve this aim the interrelations between energy security, energy economics and social cohesion are discussed. The theoretical framework of social cohesion (introduced by J. Jenson and P. Bernard is presented and applied in empirical analysis. The operationalization of empirical variables is based on economic, political and socio-cultural - activity areas, which are analyzed to verify the dichotomies between public attitudes and the actual behavior of society. These dichotomies help to distinguish six analytical dimensions, on the basis of which we created 17 empirical indicators, which analysis allows for describing the impact of Lithuanian energy security economics on social cohesion in quantitative data. The statistical analyses showed that the impact of attitudinal dimensions of energy security economics on social cohesion in Lithuania has an almost neutral effect: 3.05 (1-very negative; 3-neutral, 5-very positive. Whereas, the impact of behavioural dimensions of energy security economics on social cohesion has a negative effect: 2.47. The aggregated average of the overall impact of energy security economics on social cohesion in Lithuania has a negative effect: 2.76.

Validating Experimental Bedform Dynamics on Cohesive Sand-Mud Beds in the Dee Estuary

Science.gov (United States)

Baas, Jaco H.; Baker, Megan; Hope, Julie; Malarkey, Jonathan; Rocha, Renata

2014-05-01

Recent laboratory experiments and field measurements have shown that small quantities of cohesive clay, and in particular 'sticky' biological polymers, within a sandy substrate dramatically reduce the development rate of sedimentary bedforms, with major implications for sediment transport rate calculations and process interpretations from the sedimentary record. FURTHER INFORMATION Flow and sediment transport predictions from sedimentary structures found in modern estuaries and within estuarine geological systems are impeded by an almost complete lack of process-based knowledge of the behaviour of natural sediments that consist of mixtures of cohesionless sand and biologically-active cohesive mud. Indeed, existing predictive models are largely based on non-organic cohesionless sands, despite the fact that mud, in pure form or mixed with sand, is the most common sediment on Earth and also the most biologically active interface across a range of Earth-surface environments, including rivers and shallow seas. The multidisciplinary COHBED project uses state-of-the-art laboratory and field technologies to measure the erosional properties of mixed cohesive sediment beds and the formation and stability of sedimentary bedforms on these beds, integrating the key physical and biological processes that govern bed evolution. The development of current ripples on cohesive mixed sediment beds was investigated as a function of physical control on bed cohesion versus biological control on bed cohesion. These investigations included laboratory flume experiments in the Hydrodynamics Laboratory (Bangor University) and field experiments in the Dee estuary (at West Kirby near Liverpool). The flume experiments showed that winnowing of fine-grained cohesive sediment, including biological stabilisers, is an important process affecting the development rate, size and shape of the cohesive bedforms. The ripples developed progressively slower as the kaolin clay fraction in the sandy substrate

Cohesion Features in ESL Reading: Comparing Beginning, Intermediate and Advanced Textbooks

Science.gov (United States)

Plakans, Lia; Bilki, Zeynep

2016-01-01

This study of English as a second language (ESL) reading textbooks investigates cohesion in reading passages from 27 textbooks. The guiding research questions were whether and how cohesion differs across textbooks written for beginning, intermediate, and advanced second language readers. Using a computational tool called Coh-Metrix, textual…

Fatigue damage modeling in solder interconnects using a cohesive zone approach

NARCIS (Netherlands)

Abdul-Baqi, A.J.J.; Schreurs, P.J.G.; Geers, M.G.D.

2005-01-01

The objective of this work is to model the fatigue damage process in a solder bump subjected to cyclic loading conditions. Fatigue damage is simulated using the cohesive zone methodology. Damage is assumed to occur at interfaces modeled through cohesive zones in the material, while the bulk material

Cohesion, leadership, mental health stigmatisation and perceived barriers to care in UK military personnel.

Science.gov (United States)

Jones, Norman; Campion, Ben; Keeling, Mary; Greenberg, Neil

2018-02-01

Military research suggests a significant association between leadership, cohesion, mental health stigmatisation and perceived barriers to care (stigma/BTC). Most studies are cross sectional, therefore longitudinal data were used to examine the association of leadership and cohesion with stigma/BTC. Military personnel provided measures of leadership, cohesion, stigma/BTC, mental health awareness and willingness to discuss mental health following deployment (n = 2510) and 4-6 months later (n = 1636). At follow-up, baseline leadership and cohesion were significantly associated with stigma/BTC; baseline cohesion alone was significantly associated with awareness of and willingness to discuss mental health at follow-up. Over time, changes in perceived leadership and cohesion were significantly associated with corresponding changes in stigma/BTC levels. Stigma/BTC content was similar in both surveys; fear of being viewed as weak and being treated differently by leaders was most frequently endorsed while thinking less of a help-seeking team member and unawareness of potential help sources were least common. Effective leadership and cohesion building may help to reduce stigma/BTC in military personnel. Mental health awareness and promoting the discussion of mental health matters may represent core elements of supportive leader behaviour. Perceptions of weakness and fears of being treated differently represent a focus for stigma/BTC reduction.

Social cohesion and the smoking behaviors of adults living with children.

Science.gov (United States)

Alcalá, Héctor E; Sharif, Mienah Z; Albert, Stephanie L

2016-02-01

The smoking behavior of adults can negatively impact children through exposure to environmental tobacco smoke and by modeling this unhealthy behavior. Little research has examined the role of the social environment in smoking behaviors of adults living with children. The present study specifically analyzed the relationship between social cohesion and smoking behaviors of adults living with children. Data from the 2009 California Health Interview Survey, a random-digit dial cross-sectional survey of California Adults, were used. Adults living with children reported their levels of social cohesion and smoking behaviors (N=13,978). Logistic regression models were used to predict odds of being a current smoker or living in a household in which smoking was allowed, from social cohesion. Overall, 13% of the sample was current smokers and 3.74% lived in households in which smoking was allowed. Logistic regression models showed that each one-unit increase in social cohesion is associated with reduced odds of being a current smoker (AOR=0.92; 95% CI=0.85-0.99) and reduced odds of living in a household in which smoking is allowed (AOR=0.84; 95% CI=0.75-0.93), after controlling for sociodemographic characteristics. Among adults living with children, higher social cohesion is associated with a lower likelihood of both being and smoker and living in a home where smoking is allowed. Thus, future research is needed to better understand mechanisms that explain the relationship between social cohesion and smoking-related behavior in order to prevent smoking-related health consequences and smoking initiation among children and adults. Copyright © 2015 Elsevier Ltd. All rights reserved.

Place-based innovation in Cohesion Policy: meeting and measuring the challenges

Directory of Open Access Journals (Sweden)

Alys Solly

2016-01-01

Full Text Available This paper, prepared in conjunction with the European Union’s Open Days 2015, examines current Cohesion Policy in terms of its place-based logic, a key aspect of the new Smart Specialisation strategy platform. After discussing changing notions of urbanization and governance, which seem to be shifting Cohesion Policy towards a more performance-oriented analysis of its outcomes, the paper focuses on the question of identifying an appropriate set of indicators and measuring framework. It suggests that measurements of Cohesion Policy performance should analyse the outcomes and indicators, as well as the European and national data sources and statistics, through the lens of effectiveness and well-being.

Inhibition of protein synthesis does not antagonize induction of UV-induced sister-chromatid exchange in xeroderma pigmentosum cells

International Nuclear Information System (INIS)

Sono, Akira; Sakaguchi, Kengo.

1988-01-01

Cycloheximide strongly antagonizes the induction of sisterchromatid exchanges by ethyl methanesulfonate or mitomycin C in human skin fibroblast and xeroderma pigmentosum cells (group A). Analogous behavior has been observed in several other species including Chinese hamster and plant cells. This report documents an exception to that pattern: cycloheximide fails to antagonize UV-induced sister chromatid exchange in xeroderma pigmentosum cells, whereas it does in normal human skin fibroblast cells. A genetic defect in these cells is postulated to alter the UV-mediated DNA recombination process. (author)

Cohesion and Trauma: An Examination of a Collegiate Women's Volleyball Team

Science.gov (United States)

Fletcher, Teresa B.; Meyer, Barbara B.

2009-01-01

This study examined the effects of Adventure Based Counseling (i.e., a low-element challenge program) on the cohesion of a collegiate women's volleyball team. Results suggest postintervention improvements in team cohesion. The support created in the challenge experience also transferred to the players helping one another to grieve the untimely…

Development of a cohesion questionnaire for youth: the Youth Sport Environment Questionnaire.

Science.gov (United States)

Eys, Mark; Loughead, Todd; Bray, Steven R; Carron, Albert V

2009-06-01

The purpose of the current study was to initiate the development of a psychometrically sound measure of cohesion for youth sport groups. A series of projects were undertaken in a four-phase research program. The initial phase was designed to garner an understanding of how youth sport group members perceived the concept of cohesion through focus groups (n = 56), open-ended questionnaires (n = 280), and a literature review. In Phase 2, information from the initial projects was used in the development of 142 potential items and content validity was assessed. In Phase 3, 227 participants completed a revised 87-item questionnaire. Principal components analyses further reduced the number of items to 17 and suggested a two-factor structure (i.e., task and social cohesion dimensions). Finally, support for the factorial validity of the resultant questionnaire was provided through confirmatory factor analyses with an independent sample (n = 352) in Phase 4. The final version of the questionnaire contains 16 items that assess task and social cohesion in addition to 2 negatively worded spurious items. Specific issues related to assessing youth perceptions of cohesion are discussed and future research directions are suggested.

High frequencies of chromatid aberrations produced during G/sub 2/ in human lymphocytes by very low doses (0. 025-0. 4 Gy) of X-rays in combination with inhibitors of DNA synthesis

Energy Technology Data Exchange (ETDEWEB)

Andersson, H.C.; Kihlman, B.A. (Uppsala Univ. (Sweden). Dept. of Genetics)

1984-09-01

Whole-blood cultures of human lymphocytes were exposed in the G/sub 2/-phase (3.5 h before harvesting) to various doses of X-rays and post-treated for 3 h with inhibitors of DNA synthesis. The inhibitors used were 2'-deoxyadenosine (dAdo), hydroxyurea (HU) and 1-..beta..-D-arabinofuranosylcytosine (ara-C). To prevent deamination of dAdo by adenosine deaminase (ADA), the dAdo treatments were carried out in the presence of the ADA inhibitor coformycin. HU and ara-C were used either alone or in combination. After the 3-h inhibitor treatments, the cultures were harvested and slides prepared and analyzed for chromatid aberrations in metaphase. When the inhibitors were used at concentrations high enough to cause marked chromosome damage by themselves, very low doses of X-rays (0.025-0.2 Gy) were sufficient to produce a dramatic increase in the frequency of chromatid aberrations. High frequencies of chromatid aberrations were also obtained when cultures that had received moderate doses of X-rays (0.4-0.8 Gy) were post-treated with low inhibitor concentrations that produce no or only a few aberrations by themselves.

Investigating the relationship between leader behaviours and group cohesion within women's walking groups.

Science.gov (United States)

Caperchione, Cristina; Mummery, W Kerry; Duncan, Mitch

2011-07-01

Early research has shown that leadership behaviour is viewed as a crucial factor in successfully developing team cohesion, effectively resulting in greater team satisfaction and more positive team outcomes. However, little is understood if these same factors have an impact on physical activity groups. The purpose of this study was to investigate the relationship between leader behaviours and group cohesiveness within women's physical activity groups. Participants (N = 95) included a sub-sample of adult women who were previously involved in a women's physical activity/walking program. Participants assessed their groups' leader behaviour using items pertaining to enthusiasm, motivation, instruction and availability, and their groups' cohesiveness using the Physical Activity Group Environment Questionnaire (PAGEQ). Canonical correlation analysis was used to determine the strength of association between the four concepts of group cohesion (ATG-T, ATG-S, GI-T and GI-S) and the four items pertaining to leadership behaviour. A significant multivariate relationship was revealed between group cohesion and leadership behaviour, Wilks' lambda = 0.43, F(16,170) = 5.16, p cohesion. Although a cause-effect relationship cannot be determined, the current study can serve as a valuable template in guiding future research in examining potential mechanisms that may assist with physical activity sustainability. Crown Copyright © 2011. Published by Elsevier Ltd. All rights reserved.

Group cohesion in sports teams of different professional level

OpenAIRE

Vazha M. Devishvili; Marina O. Mdivani; Daria S. Elgina

2017-01-01

Background. Team sports are not only the most exciting sporting events. but also complex activities that make serious demands on players. The effectiveness of the team depends not only on the high level of gaming interaction. but also on the relationship between the players. The work is based on the material of sports teams and is devoted to the study of the phenomenon of group cohesion. As a basic model. the authors choose a 4-factor model that describes cohesion in sports teams. The pape...

Flow Function of Pharmaceutical Powders Is Predominantly Governed by Cohesion, Not by Friction Coefficients.

Science.gov (United States)

Leung, Lap Yin; Mao, Chen; Srivastava, Ishan; Du, Ping; Yang, Chia-Yi

2017-07-01

The purpose of this study was to demonstrate that the flow function (FFc) of pharmaceutical powders, as measured by rotational shear cell, is predominantly governed by cohesion but not friction coefficients. Driven by an earlier report showing an inverse correlation between FFc and the cohesion divided by the corresponding pre-consolidation stress (Wang et al. 2016. Powder Tech. 294:105-112), we performed analysis on a large data set containing 1130 measurements from a ring shear tester and identified a near-perfect inverse correlation between the FFc and cohesion. Conversely, no correlation was found between FFc and friction angles. We also conducted theoretical analysis and estimated such correlations based on Mohr-Coulomb failure model. We discovered that the correlation between FFc and cohesion can sustain as long as the angle of internal friction at incipient flow is not significantly larger than the angle of internal friction at steady-state flow, a condition covering almost all pharmaceutical powders. The outcome of this study bears significance in pharmaceutical development. Because the cohesion value is strongly influenced by the interparticle cohesive forces, this study effectively shows that it is more efficient to improve the pharmaceutical powder flow by lowering the interparticle cohesive forces than by lowering the interparticle frictions. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

Sister chromatid exchanges induced in CHO cells by X-rays or 5.5 MeV neutrons

International Nuclear Information System (INIS)

Bocian, E.; Rosiek, O.; Sablinski, J.; Ziemba-Zoltowska, B.

1986-01-01

The induction of sister chromatid exchanges (SCEs) by X-rays (1-9 Gy) and 5.5 MeV neutrons (0.5-4 Gy) was studied in CHO cells. A dose-dependent increase of the frequency of SCE was found for both radiations when cells with BrdUrd substituted DNA were irradiated. The similar doubling dose, approx. 4 Gy, was found for X-rays and neutrons. The increase of the SCE frequency was not clearly dependent on the dose when cells with BrdUrd unsubstituted DNA were irradiated. In this case a dose of 4 Gy enhanced the SCE frequency only by the factor of 1.3. (author)

Auto consolidated cohesive sediments erosion; Erosion des sediments cohesifs en autoconsolidation

Energy Technology Data Exchange (ETDEWEB)

Ternat, F

2007-02-15

Pollutants and suspended matters of a river can accumulate into the sedimentary column. Once deposited, they are submitted to self-weight consolidation processes, ageing and burying, leading to an increase of their erosion resistance. Pollutant fluxes can be related to sedimentary fluxes, determined by threshold laws. In this work, an erosion threshold model is suggested by introducing a cohesion force into the usual force balance. A model of cohesion is developed on the basis of interactions between argillaceous cohesive particles (clays), particularly the Van der Waals force, whose parameterization is ensured by means of granulometry and porosity. Artificial erosion experiments were performed in a recirculating erosion flume with natural cored sediments where critical shear stress measurements were performed. Other analyses provided granulometry and porosity. The results obtained constitute a good database for the literature. The model is then applied to the experimental conditions and gives good agreement with measurements. An example of the accounting for self-weight consolidation processes is finally suggested, before finishing on a Mohr like diagram dedicated to soft cohesive sediment erosion. (author)

Transformational leadership and task cohesion in sport: the mediating role of inside sacrifice.

Science.gov (United States)

Cronin, Lorcan Donal; Arthur, Calum Alexander; Hardy, James; Callow, Nichola

2015-02-01

In this cross-sectional study, we examined a mediational model whereby transformational leadership is related to task cohesion via sacrifice. Participants were 381 American (Mage = 19.87 years, SD = 1.41) Division I university athletes (188 males, 193 females) who competed in a variety of sports. Participants completed measures of coach transformational leadership, personal and teammate inside sacrifice, and task cohesion. After conducting multilevel mediation analysis, we found that both personal and teammate inside sacrifice significantly mediated the relationships between transformational leadership behaviors and task cohesion. However, there were differential patterns of these relationships for male and female athletes. Interpretation of the results highlights that coaches should endeavor to display transformational leadership behaviors as they are related to personal and teammate inside sacrifices and task cohesion.

Bedform development in mixed sand-mud: The contrasting role of cohesive forces in flow and bed

Science.gov (United States)

Baas, Jaco H.; Davies, Alan G.; Malarkey, Jonathan

2013-01-01

The majority of subaqueous sediment on Earth consists of mixtures of cohesive clay and cohesionless sand and silt, but the role of cohesion on the development and stability of sedimentary bedforms is poorly understood. The results of new laboratory flume experiments on bedform development in cohesive, mixed sand-mud beds are compared with the results of previous experiments in which cohesive forces in high concentration clay flows dominated bedform development. Even though both series of mixed sand-mud experiments were conducted at similar flow velocities, the textural and structural properties of the bedforms were sufficiently different to permit the designation of key criteria for identifying bedform generation under cohesive flows against bedform generation on cohesive substrates. These criteria are essential for improving bedform size predictions in sediment transport modelling in modern sedimentary environments and for the reconstruction of depositional processes in the geological record. The current ripples developing on the cohesive, mixed sand-mud beds, with bed mud fractions of up to 18%, were significantly smaller than equivalent bedforms in noncohesive sand. Moreover, the bedform height showed a stronger inversely proportional relationship with initial bed mud fraction than the bedform wavelength. This is in contrast with the bedforms developing under the cohesive clay flows, which tend to increase in size with increasing suspended clay concentration until the flow turbulence is fully suppressed. Selective removal of clay from the mixed beds, i.e., clay winnowing, was found to be an important process, with 82-100% clay entrained into suspension after 2 h of bedform development. This winnowing process led to the development of a sand-rich armouring layer. This armouring layer is inferred to have protected the underlying mixed sand-mud from prolonged erosion, and in conjunction with strong cohesive forces in the bed may have caused the smaller size of the

Cohesion and coordination effects on transition metal surface energies

Science.gov (United States)

Ruvireta, Judit; Vega, Lorena; Viñes, Francesc

2017-10-01

Here we explore the accuracy of Stefan equation and broken-bond model semiempirical approaches to obtain surface energies on transition metals. Cohesive factors are accounted for either via the vaporization enthalpies, as proposed in Stefan equation, or via cohesive energies, as employed in the broken-bond model. Coordination effects are considered including the saturation degree, as suggested in Stefan equation, employing Coordination Numbers (CN), or as the ratio of broken bonds, according to the bond-cutting model, considering as well the square root dependency of the bond strength on CN. Further, generalized coordination numbers CN bar are contemplated as well, exploring a total number of 12 semiempirical formulations on the three most densely packed surfaces of 3d, 4d, and 5d Transition Metals (TMs) displaying face-centered cubic (fcc), body-centered cubic (bcc), or hexagonal close-packed (hcp) crystallographic structures. Estimates are compared to available experimental surface energies obtained extrapolated to zero temperature. Results reveal that Stefan formula cohesive and coordination dependencies are only qualitative suited, but unadvised for quantitative discussion, as surface energies are highly overestimated, favoring in addition the stability of under-coordinated surfaces. Broken-bond cohesion and coordination dependencies are a suited basis for quantitative comparison, where square-root dependencies on CN to account for bond weakening are sensibly worse. An analysis using Wulff shaped averaged surface energies suggests the employment of broken-bond model using CN to gain surface energies for TMs, likely applicable to other metals.

Relationship between Family Adaptability, Cohesion and Adolescent Problem Behaviors: Curvilinearity of Circumplex Model

Science.gov (United States)

Joh, Ju Youn; Kim, Sun; Park, Jun Li

2013-01-01

Background The Family Adaptability and Cohesion Evaluation Scale (FACES) III using the circumplex model has been widely used in investigating family function. However, the criticism of the curvilinear hypothesis of the circumplex model has always been from an empirical point of view. This study examined the relationship between adolescent adaptability, cohesion, and adolescent problem behaviors, and especially testing the consistency of the curvilinear hypotheses with FACES III. Methods We used the data from 398 adolescent participants who were in middle school. A self-reported questionnaire was used to evaluate the FACES III and Youth Self Report. Results According to the level of family adaptability, significant differences were evident in internalizing problems (P = 0.014). But, in externalizing problems, the results were not significant (P = 0.305). Also, according to the level of family cohesion, significant differences were in internalizing problems (P = 0.002) and externalizing problems (P = 0.004). Conclusion The relationship between the dimensions of adaptability, cohesion and adolescent problem behaviors was not curvilinear. In other words, adolescents with high adaptability and high cohesion showed low problem behaviors. PMID:23730484

Relationship between Family Adaptability, Cohesion and Adolescent Problem Behaviors: Curvilinearity of Circumplex Model.

Science.gov (United States)

Joh, Ju Youn; Kim, Sun; Park, Jun Li; Kim, Yeon Pyo

2013-05-01

The Family Adaptability and Cohesion Evaluation Scale (FACES) III using the circumplex model has been widely used in investigating family function. However, the criticism of the curvilinear hypothesis of the circumplex model has always been from an empirical point of view. This study examined the relationship between adolescent adaptability, cohesion, and adolescent problem behaviors, and especially testing the consistency of the curvilinear hypotheses with FACES III. We used the data from 398 adolescent participants who were in middle school. A self-reported questionnaire was used to evaluate the FACES III and Youth Self Report. According to the level of family adaptability, significant differences were evident in internalizing problems (P = 0.014). But, in externalizing problems, the results were not significant (P = 0.305). Also, according to the level of family cohesion, significant differences were in internalizing problems (P = 0.002) and externalizing problems (P = 0.004). The relationship between the dimensions of adaptability, cohesion and adolescent problem behaviors was not curvilinear. In other words, adolescents with high adaptability and high cohesion showed low problem behaviors.

Corporal Punishment and Child Aggression: Ethnic-Level Family Cohesion as a Moderator.

Science.gov (United States)

Lee, Yoona; Watson, Malcolm W

2017-04-01

Ethnicity has been examined as a putative moderator between parents' use of corporal punishment and children's externalizing behaviors. Yet, the reasons for this potential ethnic-level moderator have not been fully examined. The primary objective of this study was to examine whether the effect of corporal punishment on aggression is ethnic-specific using major racial groups inside and outside the U.S. samples and how the mean levels of cohesion in family relationships as found in different ethnic groups moderate the association between mothers' use of corporal punishment and children's aggression. A total of 729 mothers who had children aged 7 to 13 years were sampled from five ethnic groups (i.e., European American, African American, Hispanic American, Korean, and Chinese). Several hypotheses were tested to examine the moderating effect of ethnic-level, family cohesion on the relation of corporal punishment to children's aggression. As expected, the mean level of family cohesion was significantly different across ethnicities. Consistent results across parallel multilevel and fixed effect models showed that high corporal punishment was associated with more aggression in all ethnicities, but there was a significant variation in the association across ethnicities, and the variation was explained by ethnic-level family cohesion. There were weaker associations between corporal punishment and child aggression among ethnic groups with high family cohesion and stronger associations among ethnic groups with low family cohesion. Ethnic/cultural variation in this study emphasizes the importance of understanding family environment of diverse ethnic groups when evaluating the influence of corporal punishment on child behavior in different ethnic/cultural contexts.

Social Capital or Social Cohesion: What Matters for Subjective Well-Being?

Science.gov (United States)

Klein, Carlo

2013-01-01

The theoretical analysis of the concepts of social capital and of social cohesion shows that social capital should be considered as a micro concept whereas social cohesion, being a broader concept than social capital, is a more appropriate concept for macro analysis. Therefore, we suggest that data on the individual level should only be used to…

Symptom fluctuations, self-esteem, and cohesion during group cognitive behaviour therapy for early psychosis.

Science.gov (United States)

Lecomte, Tania; Leclerc, Claude; Wykes, Til

2018-03-01

Group cohesion has been linked to positive changes in self-esteem and in symptoms during group psychotherapy in people with psychosis. These changes may be linked to changes in symptoms as fluctuations in self-esteem have been linked to symptom fluctuations. We aimed to determine the relationship between these three factors - group cohesion, self-esteem, and symptoms - during group cognitive behaviour therapy for psychosis (GCBTp). We hypothesized that group cohesion would precede changes in symptoms and self-esteem and that improvements in self-esteem would precede improvements in symptoms. This is an uncontrolled longitudinal study recruiting from a convenience sample within two early psychosis clinics. Sixty-six individuals from first episode of psychosis treatment programmes participated in this study and received 24 sessions of a validated GCBTp protocol. Participants answered a brief questionnaire at the end of each session, measuring their group cohesion, self-esteem, and perception of their symptoms as worse, same, or better than usual. Orthogonal polynomial contrasts for time effects were estimated with a mixed model for repeated measures with a random cluster effect and revealed a quartic trend regarding changes in symptoms over the 24 sessions. Self-esteem, symptoms, and group cohesion were strongly linked during a given session. Also, self-esteem changes predicted changes in symptoms up to two sessions later, and symptoms changes predicted self-esteem changes at the next session. Group cohesion preceded improvements in both self-esteem and symptoms; self-esteem also predicted improvements in group cohesion. These results suggest that self-esteem and symptoms influence each other during therapy, with improvements in one leading to improvements in the other. Group cohesion also appears to be an essential prerequisite to positive changes in self-esteem and symptoms during GCBTp. This study emphasizes the interrelation between self-esteem improvements and

Sex differences in the development of perceived family cohesion and depressive symptoms in Taiwanese adolescents.

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Sze, Tat-Ming; Hsieh, Pei-Jung; Lin, Sieh-Hwa; Chen, I-Jung

2013-08-01

This study investigates the progression of family cohesion perceptions and depressive symptoms during the character development stage in adolescents. Data were used from the Taiwan Youth Project. The final sample comprised 2,690 adolescents with 1,312 girls (48.8%; M age = 13.0 yr., SD = 0.5). Latent curve growth analysis was employed to explore these developments. Seventh-grade girls reported greater family cohesion and more depressive symptoms than boys, and boys reported greater growth in family cohesion than girls. However, progression of depressive symptoms was not associated with the child's sex. Higher perceived family cohesion in Grade 7 correlated with less increase of depressive symptoms from Grades 9 to 11. The long-term positive influence of family cohesion on depressive symptoms is discussed.

Cohesiveness in financial news and its relation to market volatility.

Science.gov (United States)

Piškorec, Matija; Antulov-Fantulin, Nino; Novak, Petra Kralj; Mozetič, Igor; Grčar, Miha; Vodenska, Irena; Smuc, Tomislav

2014-05-22

Motivated by recent financial crises, significant research efforts have been put into studying contagion effects and herding behaviour in financial markets. Much less has been said regarding the influence of financial news on financial markets. We propose a novel measure of collective behaviour based on financial news on the Web, the News Cohesiveness Index (NCI), and we demonstrate that the index can be used as a financial market volatility indicator. We evaluate the NCI using financial documents from large Web news sources on a daily basis from October 2011 to July 2013 and analyse the interplay between financial markets and finance-related news. We hypothesise that strong cohesion in financial news reflects movements in the financial markets. Our results indicate that cohesiveness in financial news is highly correlated with and driven by volatility in financial markets.

Cohesiveness in Financial News and its Relation to Market Volatility

Science.gov (United States)

Piškorec, Matija; Antulov-Fantulin, Nino; Novak, Petra Kralj; Mozetič, Igor; Grčar, Miha; Vodenska, Irena; Šmuc, Tomislav

2014-01-01

Motivated by recent financial crises, significant research efforts have been put into studying contagion effects and herding behaviour in financial markets. Much less has been said regarding the influence of financial news on financial markets. We propose a novel measure of collective behaviour based on financial news on the Web, the News Cohesiveness Index (NCI), and we demonstrate that the index can be used as a financial market volatility indicator. We evaluate the NCI using financial documents from large Web news sources on a daily basis from October 2011 to July 2013 and analyse the interplay between financial markets and finance-related news. We hypothesise that strong cohesion in financial news reflects movements in the financial markets. Our results indicate that cohesiveness in financial news is highly correlated with and driven by volatility in financial markets. PMID:24849598

The role of bio-physical cohesive substrates on sediment winnowing and bedform development

Science.gov (United States)

Ye, Leiping; Parsons, Daniel; Manning, Andrew

2017-04-01

Existing sediment transport and bedform size predictions for natural open-channel flows in many environments are seriously impeded by a lack of process-based knowledge concerning the dynamics of complex bed sediment mixtures comprising cohesionless sand and biologically-active cohesive muds. A series of flume experiments (14 experimental runs) with different substrate mixtures of sand-clay-EPS (Extracellular Polymeric Substance) are combined with a detailed estuarine field survey (Dee estuary, NW England) to investigate the development of bedform morphologies and characteristics of suspended sediment over bio-physical cohesive substrates. The experimental results indicate that winnowing and sediment sorting can occur pervasively in bio-physical cohesive sediment - flow systems. Importantly however, the evolution of the bed and bedform dynamics, and hence turbulence production, is significantly reduced as bed substrate cohesivity increases. The estuarine subtidal zone survey also revealed that the bio-physical cohesion provided by both the clay and microorganism fractions in the bed plays a significant role in controlling the interactions between bed substrate and sediment suspension, deposition and bedform generation. The work will be presented here concludes by outlining the need to extend and revisit the effects of cohesivity in morphodynamic systems and the sets of parameters presently used in numerical modelling, particularly in the context of the impact of climate change on estuarine and coastal systems.

The Corporate Stake in Social Cohesion

Science.gov (United States)

Oketch, Moses O.

2005-01-01

Corporate Social Responsibility (CSR) is a function that transcends, but includes, making profits, creating jobs, and producing goods and services. The effectiveness with which corporations perform this function determines their contribution (or lack of contribution) to social cohesion. This article therefore presents a discussion of some of the…

Numerical insight into the micromechanics of jet erosion of a cohesive granular material

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Cuéllar Pablo

2017-01-01

Full Text Available Here we investigate the physical mechanisms behind the surface erosion of a cohesive granular soil induced by an impinging jet by means of numerical simulations coupling fluid and grains at the microscale. The 2D numerical model combines the Discrete Element and Lattice Boltzmann methods (DEM-LBM and accounts for the granular cohesion with a contact model featuring a paraboloidal yield surface. Here we review first the hydrodynamical conditions imposed by the fluid jet on a solid granular packing, turning then the attention to the impact of cohesion on the erosion kinetics. Finally, the use of an additional subcritical debonding damage model based on the work of Silvani and co-workers provides a novel insight into the internal solicitation of the cohesive granular sample by the impinging jet.

Numerical insight into the micromechanics of jet erosion of a cohesive granular material

Science.gov (United States)

Cuéllar, Pablo; Benseghier, Zeyd; Luu, Li-Hua; Bonelli, Stéphane; Delenne, Jean-Yves; Radjaï, Farhang; Philippe, Pierre

2017-06-01

Here we investigate the physical mechanisms behind the surface erosion of a cohesive granular soil induced by an impinging jet by means of numerical simulations coupling fluid and grains at the microscale. The 2D numerical model combines the Discrete Element and Lattice Boltzmann methods (DEM-LBM) and accounts for the granular cohesion with a contact model featuring a paraboloidal yield surface. Here we review first the hydrodynamical conditions imposed by the fluid jet on a solid granular packing, turning then the attention to the impact of cohesion on the erosion kinetics. Finally, the use of an additional subcritical debonding damage model based on the work of Silvani and co-workers provides a novel insight into the internal solicitation of the cohesive granular sample by the impinging jet.

Family Cohesion in the Lives of Mexican American and European American Parents

Science.gov (United States)

Behnke, Andrew O.; MacDermid, Shelley M.; Coltrane, Scott L.; Parke, Ross D.; Duffy, Sharon; Widaman, Keith F.

2008-01-01

This study investigated similarities and differences in relations between stress and parenting behaviors for 509 Mexican American and European American fathers and mothers in Southern California. Our model posited that family cohesion mediates the relation between stressors and parenting behavior, and we found that family cohesion strongly…

Social cohesion through football: a quasi-experimental mixed methods design to evaluate a complex health promotion program.

Science.gov (United States)

Nathan, Sally; Bunde-Birouste, Anne; Evers, Clifton; Kemp, Lynn; MacKenzie, Julie; Henley, Robert

2010-10-05

Football United program poses challenges for measurement, and requires the study design to be responsive to the dynamic nature of the program and context. Assessment of change is needed at multiple levels, drawing on mixed methods and multidisciplinary approaches in implementation and evaluation. Attention to these challenges has underpinned the design and methods in the Social Cohesion through Football study, which will use a unique and innovative combination of measures that have not been applied together previously in social inclusion/cohesion and sport and social inclusion/cohesion program research.

Social cohesion through football: a quasi-experimental mixed methods design to evaluate a complex health promotion program

Directory of Open Access Journals (Sweden)

Kemp Lynn

2010-10-01

also be solicited. Discussion The complexity of the Football United program poses challenges for measurement, and requires the study design to be responsive to the dynamic nature of the program and context. Assessment of change is needed at multiple levels, drawing on mixed methods and multidisciplinary approaches in implementation and evaluation. Attention to these challenges has underpinned the design and methods in the Social Cohesion through Football study, which will use a unique and innovative combination of measures that have not been applied together previously in social inclusion/cohesion and sport and social inclusion/cohesion program research.

Bedform development and morphodynamics in mixed cohesive sediment substrates: the importance of winnowing and flocculation

Science.gov (United States)

Ye, Leiping; Parsons, Daniel; Manning, Andrew

2016-04-01

There remains a lack of process-based knowledge of sediment dynamics within flows over bedforms generated in complex mixtures of cohesionless sand and biologically-active cohesive muds in natural estuarine flow systems. The work to be presented forms a part of the UK NERC "COHesive BEDforms (COHBED)" project which aims to fill this gap in knowledge. Herein results from a field survey in sub-tidal zone of Dee estuary (NW, England) and a set of large-scale laboratory experiments, conducted using mixtures of non-cohesive sands, cohesive muds and Xanthan gum (as a proxy for the biological stickiness of Extracellular Polymeric Substances (EPS)) will be presented. The results indicate the significance of biological-active cohesive sediments in controlling winnowing rates and flocculation dynamics, which contributes significantly to rates of bedform evolution.

An Investigation into the Use of Cohesive Devises in Iranian High School EFL Textbooks

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Mansour Shabani

2015-07-01

Full Text Available The present study aimed at probing into the use of grammatical and lexical cohesive subdevices in Iranian high school EFL textbooks. To this end, the reading sections of three high school EFL textbooks and one pre-university EFL textbook were analyzed in terms of the distribution of grammatical and lexical cohesive subdevices. The results of One-way ANOVA illustrated that: athere are no significant differences among the frequencies of grammatical cohesive subdevices across grade 1 high school EFL textbook and the pre-university EFL textbook, bthere are significant differences among the frequencies of grammatical cohesive subdevices across grades 2 and 3 high school EFL textbooks. Moreover, the results of Chi-Square test showed that the significant values of all of the lexical cohesive subdevices were higher than .05 across each of the Iranian EFL high school textbooks. These findings can be beneficial for textbook writers, materials developers and EFL teachers.

A Molecular-Scale Understanding of Cohesion and Fracture in P3HT:Fullerene Blends

KAUST Repository

Tummala, Naga Rajesh

2015-04-21

Quantifying cohesion and understanding fracture phenomena in thin-film electronic devices are necessary for improved materials design and processing criteria. For organic photovoltaics (OPVs), the cohesion of the photoactive layer portends its mechanical flexibility, reliability, and lifetime. Here, the molecular mechanism for the initiation of cohesive failure in bulk heterojunction (BHJ) OPV active layers derived from the semiconducting polymer poly-(3-hexylthiophene) [P3HT] and two mono-substituted fullerenes is examined experimentally and through molecular-dynamics simulations. The results detail how, under identical conditions, cohesion significantly changes due to minor variations in the fullerene adduct functionality, an important materials consideration that needs to be taken into account across fields where soluble fullerene derivatives are used.

Can consumption of raw vegetables decrease the count of sister chromatid exchange? Results from a cross-sectional study in Krakow, Poland

OpenAIRE

Galas, Aleksander; Cebulska-Wasilewska, Antonina

2014-01-01

Background Sister chromatid exchange (SCE) is a widely used sensitive cytogenetic biomarker of exposure to genotoxic and cancerogenic agents. Results of human monitoring studies and cytogenetic damage have revealed that biological effects of genotoxic exposures are influenced by confounding factors related to life-style. Vegetable and fruit consumption may play a role, but available results are not consistent. The purpose of the study was to investigate the effect of consumption of raw and co...

Multiculturalism and Community Cohesion in Britain: The Case of Arab Minority

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Mohamed Benitto

2015-11-01

Full Text Available This article falls within the scope of debate about 'Community Cohesion' in Britain. Community cohesion is at the centre of public policy initiated in response to the urban disturbances in northern towns. Many official reports pointed out that lack of community cohesion is an element jeopardizing security and safe coexistence. In this sense, this article explores hindrances to intergroup coexistence, given that this issue is the main concern in this pluralist society since the attacks in London in July, 7, 2005, through the study of intercultural relations between Arab minority of London and mainstream society in Britain. This research adopts an approach which aims to contribute to the understanding of the reasons hampering community cohesion through juxtaposition of viewpoints of both the minority and majority group. The originality of this approach lies in the fact that it tackles the issue of integration from two sided points of view: the point of the majority group and the point of view of the minority group; unlike most literature on intergroup relations which basically focus on the integration of the minority and its daptation to the dominant culture.

Social cohesion and integration: Learning active citizenship

NARCIS (Netherlands)

Jansen, T.J.M.; Chioncel, N.E.; Dekkers, H.P.J.M.

2006-01-01

This article starts from a conceptual clarification of the notions social integration and social cohesion as a prerequisite for the reorientation of citizenship education. Turning away from uncritically reproduced assumptions represented in mainstream `deficiency discourse', the article first

Alcohol Use Severity Among Adult Hispanic Immigrants: Examining the Roles of Family Cohesion, Social Support, and Gender.

Science.gov (United States)

Cano, Miguel Ángel; Sánchez, Mariana; Rojas, Patria; Ramírez-Ortiz, Daisy; Polo, Katherine L; Romano, Eduardo; De La Rosa, Mario

2018-03-21

This study examined (a) the direct association of family cohesion on alcohol use severity among adult Hispanic immigrants; (b) the indirect association of family cohesion on alcohol use severity via social support; and (c) if gender moderates the direct and indirect associations between family cohesion and alcohol use severity. Mediation and moderation analyses were conducted on a cross-sectional sample of 411 (men = 222, women = 189) participants from Miami-Dade, Florida. Findings indicate that higher family cohesion was directly associated with higher social support and lower alcohol use severity. Higher social support was also directly associated with lower alcohol use severity. Additionally, family cohesion had an indirect association with alcohol use severity via social support. Moderation analyses indicated that gender moderated the direct association between family cohesion and alcohol use severity, but did not moderate the indirect association. Some potential clinical implications may be that strengthening family cohesion may enhance levels of social support, and in turn, lower alcohol use severity among adult Hispanic immigrants. Furthermore, strengthening family cohesion may be especially beneficial to men in efforts to lower levels of alcohol use severity.

An acoustic method for predicting relative strengths of cohesive sediment deposits

Science.gov (United States)

Reed, A. H.; Sanders, W. M.

2017-12-01

Cohesive sediment dynamics are fundamentally determined by sediment mineralogy, organic matter composition, ionic strength of water, and currents. These factors work to bind the cohesive sediments and to determine depositional rates. Once deposited the sediments exhibit a nonlinear response to stress and they develop increases in shear strength. Shear strength is critically important in resuspension, transport, creep, and failure predictions. Typically, shear strength is determined by point measurements, both indirectly from free-fall penetrometers or directly on cores with a shear vane. These values are then used to interpolate over larger areas. However, the remote determination of these properties would provide continuos coverage, yet it has proven difficult with sonar systems. Recently, findings from an acoustic study on cohesive sediments in a laboratory setting suggests that cohesive sediments may be differentiated using parametric acoustics; this method pulses two primary frequencies into the sediment and the resultant difference frequency is used to determine the degree of acoustic nonlinearity within the sediment. In this study, two marine clay species, kaolinite and montmorillonite, and two biopolymers, guar gum and xanthan gum were mixed to make nine different samples. The samples were evaluated in a parametric acoustic measurement tank. From the parametric acoustic measurements, the quadratic nonlinearity coefficient (beta) was determined. beta was correlated with the cation exchange capacity (CEC), an indicator of shear strength. The results indicate that increased acoustic nonlinearity correlates with increased CEC. From this work, laboratory measurements indicate that this correlation may be used evaluate geotechnical properties of cohesive sediments and may provide a means to predict sediment weakness in subaqueous environments.

Topographic Signatures of Meandering Rivers with Differences in Outer Bank Cohesion

Science.gov (United States)

Kelly, S. A.; Belmont, P.

2014-12-01

Within a given valley setting, interactions between river hydraulics, sediment, topography, and vegetation determine attributes of channel morphology, including planform, width and depth, slope, and bed and bank properties. These feedbacks also govern river behavior, including migration and avulsion. Bank cohesion, from the addition of fine sediment and/or vegetation has been recognized in flume experiments as a necessary component to create and maintain a meandering channel planform. Greater bank cohesion slows bank erosion, limiting the rate at which a river can adjust laterally and preventing so-called "runaway widening" to a braided state. Feedbacks of bank cohesion on channel hydraulics and sediment transport may thus produce distinct topographic signatures, or patterns in channel width, depth, and point bar transverse slope. We expect that in bends of greater outer bank cohesion the channel will be narrower, deeper, and bars will have greater transverse slopes. Only recently have we recognized that biotic processes may imprint distinct topographic signatures on the landscape. This study explores topographic signatures of three US rivers: the lower Minnesota River, near Mankato, MN, the Le Sueur River, south central MN, and the Fall River, Rocky Mountain National Park, CO. Each of these rivers has variability in outer bank cohesion, quantified based on geotechnical and vegetation properties, and in-channel topography, which was derived from rtkGPS and acoustic bathymetry surveys. We present methods for incorporating biophysical feedbacks into geomorphic transport laws so that models can better simulate the spatial patterns and variability of topographic signatures.

Automated Behavior and Cohesion Assessment Tools, Phase II

Data.gov (United States)

National Aeronautics and Space Administration — An important consideration of long duration space flight operations is interpersonal dynamics that effect crew cohesion and performance. Flight surgeons have stated...

Leader Behaviors, Group Cohesion, and Participation in a Walking Group Program.

Science.gov (United States)

Izumi, Betty T; Schulz, Amy J; Mentz, Graciela; Israel, Barbara A; Sand, Sharon L; Reyes, Angela G; Hoston, Bernadine; Richardson, Dawn; Gamboa, Cindy; Rowe, Zachary; Diaz, Goya

2015-07-01

Less than half of all U.S. adults meet the 2008 Physical Activity Guidelines. Leader behaviors and group cohesion have been associated with increased participation or adherence in sports team and exercise class settings. Physical activity interventions in community settings that encompass these factors may enhance intervention adherence. The purpose of this study is to examine the impact of Community Health Promoter leader behaviors and group cohesion on participation in a walking group intervention among racially/ethnically diverse adults in low to moderate-income communities in Detroit, Michigan. Data for the current study were drawn from the Walk Your Heart to Health (WYHH) data set. WYHH was a multisite cluster RCT with a lagged intervention and outcome measurements at baseline and 4, 8, and 32 weeks. Pooled survey data from both intervention arms were used for the current study. Data were analyzed between August 2013 and October 2014. A total of 603 non-Hispanic black, non-Hispanic white, and Hispanic adults across five cohorts that began the 32-week WYHH intervention between March 2009 and October 2011. The intervention was a 32-week walking group program hosted by community- and faith-based organizations and facilitated by Community Health Promoters. Walking groups met three times per week for 90 minutes per session. To promote participation in or adherence to WYHH, Community Health Promoters used evidence-based strategies to facilitate group cohesion. Group members assumed increasing leadership responsibility for facilitating sessions over time. Participation in WYHH as measured by consistency of attendance. Community Health Promoter leader behaviors were positively associated with participation in WYHH. Social but not task cohesion was significantly associated with consistent participation. Social cohesion may mediate the relationship between leader behaviors and walking group participation. Providing leaders with training to build socially cohesive groups

Family cohesion and posttraumatic intrusion and avoidance among war veterans: a 20-year longitudinal study.

Science.gov (United States)

Zerach, Gadi; Solomon, Zahava; Horesh, Danny; Ein-Dor, Tsachi

2013-02-01

The bi-directional relationships between combat-induced posttraumatic symptoms and family relations are yet to be understood. The present study assesses the longitudinal interrelationship of posttraumatic intrusion and avoidance and family cohesion among 208 Israeli combat veterans from the 1982 Lebanon War. Two groups of veterans were assessed with self-report questionnaires 1, 3 and 20 years after the war: a combat stress reaction (CSR) group and a matched non-CSR control group. Latent Trajectories Modeling showed that veterans of the CSR group reported higher intrusion and avoidance than non-CSR veterans at all three points of time. With time, there was a decline in these symptoms in both groups, but the decline was more salient among the CSR group. The latter also reported lower levels of family cohesion. Furthermore, an incline in family cohesion levels was found in both groups over the years. Most importantly, Autoregressive Cross-Lagged Modeling among CSR and non-CSR veterans revealed that CSR veterans' posttraumatic symptoms in 1983 predicted lower family cohesion in 1985, and lower family cohesion, in turn, predicted posttraumatic symptoms in 2002. The findings suggest that psychological breakdown on the battlefield is a marker for future family cohesion difficulties. Our results lend further support for the bi-directional mutual effects of posttraumatic symptoms and family cohesion over time.

Amount of sister chromatid exchanges and survival of Chinese hamster V79-4 cells after irradiation with 0,7 MeV neutrons

International Nuclear Information System (INIS)

Lapidus, I.L.; Nasonova, E.A.

1987-01-01

The dependence of the survival and induction of sister chromatid exchanges (SCEs) in Chinese hamster V79-4 cells on the dose of γ-rays and neutrons with average energy 0.7 MeV has been analysed. The value of RBE for neutrons was 5.5. It has been shown that the number of SCE increased with the dose of γ-irradiation and no induction could be detected after neutron irradiation

Leadership, cohesion and groupthink

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Iurchevici Iulia

2016-09-01

Full Text Available The Groupthink Phenomenon refers to the tendency of the members of a group to reach solidarity and cohesion, the trend that makes to bypass any questions which would lead to disputes. In such cases, if the members expect counter-arguments regarding a certain issue, they avoid to raise the matter. If it is believed that a question cannot be answered – it isn’t asked. Originally, Janis the author of the term, explains this process through the environment that has been established within groups that are in the leading position, but later, puts a strong emphasis towards the tendency to maintain the unanimity of the decision of the group. As preceding conditions of this decision-making process are listed the following: the high cohesion of the group, its isolation from other external sources of information, the lack of an impartial leadership, lack of appropriate legal framework and procedures in the decision - making process, and also “homogeneity of members, background and their ideology”. The Groupthink is manifested by: Illusion of Invulnerability, Collective Rationalization, Illusion of morality, Out – Group Stereotypes, Strong pressures towards conformism, Self – Censorship, Illusions of unanimity, and the presence of “Mind Guards”. In order to understand the decisions of a group, it is important that some analysis of Groupthink to be done, because in this way, can be controlled or eliminated the communicational distortion that occurs at a time among members forming these groups.

Noncontact Cohesive Swimming of Bacteria in Two-Dimensional Liquid Films.

Science.gov (United States)

Li, Ye; Zhai, He; Sanchez, Sandra; Kearns, Daniel B; Wu, Yilin

2017-07-07

Bacterial swimming in confined two-dimensional environments is ubiquitous in nature and in clinical settings. Characterizing individual interactions between swimming bacteria in 2D confinement will help to understand diverse microbial processes, such as bacterial swarming and biofilm formation. Here we report a novel motion pattern displayed by flagellated bacteria in 2D confinement: When two nearby cells align their moving directions, they tend to engage in cohesive swimming without direct cell body contact, as a result of hydrodynamic interaction but not flagellar intertwining. We further found that cells in cohesive swimming move with higher directional persistence, which can increase the effective diffusivity of cells by ∼3 times as predicted by computational modeling. As a conserved behavior for peritrichously flagellated bacteria, cohesive swimming in 2D confinement may be key to collective motion and self-organization in bacterial swarms; it may also promote bacterial dispersal in unsaturated soils and in interstitial space during infections.

In vivo persistence of sister chromatid exchanges (SCE) induced by gamma rays in mouse bone marrow cells

International Nuclear Information System (INIS)

Morales-Ramirez, P.; Vallarino-Kelly, T.; Rodriguez-Reyes, R.

1984-01-01

The sister chromatid exchange (SCE) frequencies induced in bone marrow cells by in vivo irradiation with gamma rays before or after bromodeoxyuridine (BrdUrd) incorporation were compared. The frequency of SCE at different postirradiation times was also measured in bone marrow cells in vivo, irradiated before BrdUrd incorporation. Increased sensitivity to SCE induction by radiation was found in cells after BrdUrd incorporation for one cycle when compared with cells irradiated before BrdUrd incorporation. The increased SCE frequency persisted for at least 72 hr after the initial irradiation, implying that the gamma ray-induced lesion(s) capable of eliciting an SCE are persistent and cannot be easily repaired

Competition and social cohesion

Directory of Open Access Journals (Sweden)

Mario Libertini

2014-03-01

Full Text Available "Competition" and "social cohesion" are both protected by E.U. and Italian laws. The author moves from the analysis of the meaning of these two concepts, in order to reflect on their compatibility and the way to conciliate them. The central problem - in the opinion of the Author - is to abandon the myth of spontaneous markets' order and to rebuild a political order able to maintain and support, as far as possible, the competitive market economy, but also to govern economic processes in critical moments and situations.

Simulation of debonding in Al/epoxy T-peel joints using a potential-based cohesive zone model

KAUST Repository

Alfano, Marco

2011-06-10

In this work, a cohesive zone model of fracture is employed to study debonding in plastically deforming Al/epoxy T-peel joints. In order to model the adhesion between the bonded metal strips, the Park-Paulino-Roesler (PPR) potential based cohesive model (J Mech Phys Solids, 2009;57:891-908) is employed, and interface elements are implemented in a finite element com-mercial code. A study on the influence of the cohesive properties (i.e. cohesive strength, fracture energy, shape parameter and slope indicator) on the predicted peel-force versus displacement plots reveals that the numerical results are mostly sensitive to cohesive strength and fracture energy. In turn, these parameters are tuned until a match between experimental and simulated load displacement curves is achieved.

Simulation of debonding in Al/epoxy T-peel joints using a potential-based cohesive zone model

KAUST Repository

Alfano, Marco; Furgiuele, Franco; Lubineau, Gilles; Paulino, Glaucio H.

2011-01-01

In this work, a cohesive zone model of fracture is employed to study debonding in plastically deforming Al/epoxy T-peel joints. In order to model the adhesion between the bonded metal strips, the Park-Paulino-Roesler (PPR) potential based cohesive model (J Mech Phys Solids, 2009;57:891-908) is employed, and interface elements are implemented in a finite element com-mercial code. A study on the influence of the cohesive properties (i.e. cohesive strength, fracture energy, shape parameter and slope indicator) on the predicted peel-force versus displacement plots reveals that the numerical results are mostly sensitive to cohesive strength and fracture energy. In turn, these parameters are tuned until a match between experimental and simulated load displacement curves is achieved.

The effect of coarse gravel on cohesive sediment entrapment in an annular flume

Directory of Open Access Journals (Sweden)

K. Glasbergen

2015-03-01

Full Text Available While cohesive sediment generally represents a small fraction (16 Pa, cohesive materials trapped within the gravel bed will be entrained and transported into the Glenmore Reservoir, where sediment-associated nutrients may pose treatment challenges to the drinking water supply.

Numerical model of glulam beam delamination in dependence on cohesive strength

Science.gov (United States)

Kawecki, Bartosz; Podgórski, Jerzy

2018-01-01

This paper presents an attempt of using a finite element method for predicting delamination of a glue laminated timber beam through a cohesive layer. There were used cohesive finite elements, quadratic stress damage initiation criterion and mixed mode energy release rate failure model. Finite element damage was equal to its complete stiffness degradation. Timber material was considered to be an orthotropic with plastic behaviour after reaching bending limit.

A cohesive zone framework for environmentally assisted fatigue

DEFF Research Database (Denmark)

del Busto, Susana; Betegón, Covadonga; Martínez Pañeda, Emilio

2017-01-01

We present a compelling finite element framework to model hydrogen assisted fatigue by means of a hydrogen- and cycle-dependent cohesive zone formulation. The model builds upon: (i) appropriate environmental boundary conditions, (ii) a coupled mechanical and hydrogen diffusion response, driven...... by chemical potential gradients, (iii) a mechanical behavior characterized by finite deformation J2 plasticity, (iv) a phenomenological trapping model, (v) an irreversible cohesive zone formulation for fatigue, grounded on continuum damage mechanics, and (vi) a traction-separation law dependent on hydrogen...... coverage calculated from first principles. The computations show that the present scheme appropriately captures the main experimental trends; namely, the sensitivity of fatigue crack growth rates to the loading frequency and the environment. The role of yield strength, work hardening, and constraint...

Regions and the Territorial Cohesion

Directory of Open Access Journals (Sweden)

Ioan Ianos

2013-08-01

Full Text Available Territorial cohesion is an important target of European Union, constantly promoted by its institutions and their representatives. In the context of the Europe 2020 strategy, one of the most important support documents, the region represents a very important issue, being considered to be the key to its successfulness. The region is seen as a support for the smart growth and all the operational policy concepts try to make use of the spatial potential, by taking better account of the territorial specificities. Two main questions play attention: the need to transform the present-day developmental regions into administrative ones is a priority? What kind of regionalization it must to be promoted? Correlating these issues with already defined territorial cohesion, the administrative region is a real tool for the future territorial development. The experience of the last 14 years asks urgently the building of a new territorial administrative reform, giving competences to regions. For instant, each development region is a construction resulted from a free association of the counties. Their role in the regional development is much reduced one, because their regional councils are not elected; decisions taken at this level are consultative for the social, economical, cultural or political actors.

Team cohesion and ethnic-cultural identity in adolescent migrant athletes

DEFF Research Database (Denmark)

Morela, Eleftheria; Hatzigeorgiadis, Antonis; Kouli, Olga

2013-01-01

The purpose of this study was to examine the role of sport participation in the social integration of adolescents with non-dominant ethnic and cultural backgrounds. In particular, this study investigated the relationship between team cohesion and ethnic-cultural identity. Participants were 83 young...... migrant athletes (mean age 15.60 years). Participants completed the Ethnic/Cultural Identity Salience Questionnaire and the Youth Sport Environment Questionnaire. Regression analyses showed that cohesion negatively predicted feelings of fringe and lack of interaction. Our findings suggest that sport...

Spilling over: Partner parenting stress as a predictor of family cohesion in parents of adolescents with developmental disabilities.

Science.gov (United States)

Mitchell, Darcy B; Szczerepa, Alexandra; Hauser-Cram, Penny

2016-01-01

Family cohesion relates to positive outcomes for both parents and children. Maintaining cohesion may be especially challenging for families of adolescents with developmental disabilities, yet this has been studied infrequently in this group. We investigated cohesion in these families, particularly with respect to partner stress, using the notion of the 'spillover effect' as a model. Adolescents with disabilities and their parents participated. Parents reported on teen adaptive and problem behaviours and on marital satisfaction, parenting stress, and family cohesion. The stress of one partner was tested as a predictor of the quality of family cohesion reported by the other. Adolescent behaviour problems were negative predictors of family cohesion in mothers, and marital satisfaction positively predicted cohesion for both parents. Above other factors, greater partner stress predicted poorer family cohesion for both fathers and mothers. Marital satisfaction acted as a suppressor of this relation. To improve the overall climate of families, care providers should take into consideration individual relationships, including the marital relationship. In addition, the possibility of spillover from one individual to another should be recognized as a factor in family functioning. Family-centred practices are likely to lead to greater feelings of cohesion and overall better individual and family well-being. Copyright © 2015 Elsevier Ltd. All rights reserved.

Outdoor activities and depressive symptoms in displaced older adults following natural disaster: community cohesion as mediator and moderator.

Science.gov (United States)

Chao, Shiau-Fang

2016-09-01

This investigation examined whether community cohesion mediates or moderates the relationship between outdoor activities and depressive symptoms in older adults displaced by Typhoon Morakot in Taiwan. This cross-sectional study included 292 adults aged 65 years or older who were relocated to permanent houses after Typhoon Morakot damaged their homes on 8th August 2009. Multiple regression analysis was applied to test the role of community cohesion on the association between outdoor activities and depressive symptoms. The sample of displaced older adults displayed higher prevalence of depressive symptoms than the average for community dwelling older people in Taiwan. Community cohesion fully mediated the relationship between outdoor activities and depressive symptoms. Community cohesion also moderated the relationship between outdoor activities and depressive symptoms. Community cohesion occupies a key role on the link between outdoor activities and depressive symptoms. Participation in outdoor activities was associated positively with community cohesion, while high community cohesion was related negatively to depressive symptoms. Additionally, the benefit of outdoor activities to fewer depressive symptoms only manifested in older adults with high community cohesion. Programs and services should be designed to enhance community cohesion in order to maximize the benefit of outdoor activities to the mental health of displaced older adults after natural disasters.

The effect of coarse gravel on cohesive sediment entrapment in an annular flume

Science.gov (United States)

Glasbergen, K.; Stone, M.; Krishnappan, B.; Dixon, J.; Silins, U.

2015-03-01

While cohesive sediment generally represents a small fraction (armour layer of the gravel bed (>16 Pa), cohesive materials trapped within the gravel bed will be entrained and transported into the Glenmore Reservoir, where sediment-associated nutrients may pose treatment challenges to the drinking water supply.

How to deal with legal uncertainty: Managing and Audit Authorities in Cohesion Policy

NARCIS (Netherlands)

Meuleman, Lysette; Brenninkmeijer, A.F.M.

2017-01-01

Cohesion policy (ERDF, ESF and CF) is implemented in a system of shared management. Signals received from some EU countries indicate that legal uncertainty is created for beneficiaries of cohesion policy funds due to differences in interpretation of, mostly national, regulation. This is a problem

Group Cohesion in Experiential Growth Groups

Science.gov (United States)

Steen, Sam; Vasserman-Stokes, Elaina; Vannatta, Rachel

2014-01-01

This article explores the effect of web-based journaling on changes in group cohesion within experiential growth groups. Master's students were divided into 2 groups. Both used a web-based platform to journal after each session; however, only 1 of the groups was able to read each other's journals. Quantitative data collected before and…

[Team cohesiveness: opinions of a group of primary health care professionals from Salamanca].

Science.gov (United States)

González, F J; de Cabo, A; Morán, M J; Manzano, J M

1993-04-01

To assess the view of a group of Primary care professionals on their level of perception of group cohesiveness in their teams' work dynamic. A descriptive and sectional study. Four urban health centres in Salamanca with a recognised teaching activity. Both health professionals and those outside the Health Service, working in Primary Care, who had been members of their teams for more than a year (N = 90). Descriptive statistics and "Chi squared" tests were employed. 72%. A high level of agreement on the need for team work (95.23%). They perceived their group cohesiveness as being very low (84.21% affirmed that they encounter problems of cohesiveness). The main statements concerning this lack of cohesiveness were: "lack of common objectives" (25.5%), "intolerance between workers" (20.13%), "work not shared" (19.46%) and "the taking of decisions individually" (19.44%). The main causes given were: lack of support from Management (23.74%) and too little training for team work (21.58%). There is a high degree of conviction that the team work model is the most efficacious way of developing Primary Care. However in three of the four teams questioned, there were serious problems preventing the teams' reaching an adequate level of group cohesiveness.

Acute wood or coal exposure with carbon monoxide intoxication induces sister chromatid exchange

Energy Technology Data Exchange (ETDEWEB)

Ozturk, S.; Vatansever, S.; Cefle, K.; Palanduz, S.; Guler, K.; Erten, N.; Erk, O.; Karan, M.A.; Tascioglu, C. [University of Istanbul, Istanbul (Turkey). Istanbul Faculty of Medicine

2002-07-01

The object of this study was to investigate the genotoxic effect of acute overexposure to combustion products originating from coal or wood stoves in patients presenting with acute carbon monoxide intoxication. The authors analyzed the frequency of sister chromatid exchange and the carboxyhemoglobin concentration in 20 consecutive patients without a history of smoking or drug use who had been treated in the Emergency Care Unit of Istanbul Medical Faculty due to acute carbon monoxide intoxication. All of these cases were domestic accidents due to dysfunctioning coal or wood stoves. The results were compared with a control group of 20 nonsmoking, nondrug-using healthy individuals matched for age, sex, and absence of other chemical exposure. It was concluded that acute exposure to combustion products of wood or coal is genotoxic to DNA. Potential causes of genotoxicity include known mutagenic compounds present in coal or wood smoke and ash, oxygen radicals formed during combustion, as well as hypoxic and reperfusion injury mechanisms initiated by carbon monoxide intoxication.

Development of an evaluation method for fracture mechanical tests on small samples based on a cohesive zone model; Entwicklung einer Auswertemethode fuer bruchmechanische Versuche an kleinen Proben auf der Basis eines Kohaesivzonenmodells

Energy Technology Data Exchange (ETDEWEB)

Mahler, Michael

2016-07-01

The safety and reliability of nuclear power plants of the fourth generation is an important issue. It is based on a reliable interpretation of the components for which, among other fracture mechanical material properties are required. The existing irradiation in the power plants significantly affects the material properties which therefore need to be determined on irradiated material. Often only small amounts of irradiated material are available for characterization. In that case it is not possible to manufacture sufficiently large specimens, which are necessary for fracture mechanical testing in agreement with the standard. Small specimens must be used. From this follows the idea of this study, in which the fracture toughness can be predicted with the developed method based on tests of small specimens. For this purpose, the fracture process including the crack growth is described with a continuum mechanical approach using the finite element method and the cohesive zone model. The experiments on small specimens are used for parameter identification of the cohesive zone model. The two parameters of the cohesive zone model are determined by tensile tests on notched specimens (cohesive stress) and by parameter fitting to the fracture behavior of smalls specimens (cohesive energy). To account the different triaxialities of the specimens, the cohesive stress is used depending on the triaxiality. After parameter identification a large specimen can be simulated with the cohesive zone parameters derived from small specimens. The predicted fracture toughness of this big specimen fulfills the size requirements in the standard (ASTM E1820 or ASTM E399) in contrast to the small specimen. This method can be used for ductile and brittle material behavior and was validated in this work. In summary, this method offers the possibility to determine the fracture toughness indirectly based on small specimen testing. Main advantage is the low required specimen volume. Thereby massively

The Process Architecture of EU Territorial Cohesion Policy

Directory of Open Access Journals (Sweden)

Andreas Faludi

2010-08-01

Full Text Available When preparing the European Spatial Development Perspective (ESDP, Member States were supported by the European Commission but denied the EU a competence in the matter. Currently, the Treaty of Lisbon identifies territorial cohesion as a competence shared between the Union and the Member States. This paper is about the process architecture of territorial cohesion policy. In the past, this architecture resembled the Open Method of Coordination (OMC which the White Paper on European Governance praised, but only in areas where there was no EU competence. This reflected zero-sum thinking which may continue even under the Lisbon Treaty. After all, for as long as territorial cohesion was not a competence, voluntary cooperation as practiced in the ESDP process was pursued in this way. However, the practice of EU policies, even in areas where there is an EU competence, often exhibits features of the OMC. Surprisingly effective innovations hold the promise of rendering institutions of decision making comprehensible and democratically accountable. In the EU as a functioning polity decision making is thus at least part deliberative so that actors’ preferences are transformed by the force of the better argument. This brings into focus the socialisation of the deliberators into epistemic communities. Largely an informal process, this is reminiscent of European spatial planning having been characterised as a learning process.

The Role of Lexical Cohesion in Writing Quality

Directory of Open Access Journals (Sweden)

Hmoud Alotaibi

2015-01-01

Full Text Available The idea of whether repetition has any relation with the writing quality of the text has remained an issue that intrigues a number of scholars in linguistics and in writing studies. Michael Hoey (1991, Halliday and Hasan (1976 are two prominent works in presenting detailed and thoughtful analysis of repetition occurrences in the text. This study uses a model of lexical cohesion proposed by Witte and Faigley (1981 which itself is based on the taxonomies of cohesive ties presented by Halliday and Hasan (1976.  The model deals with lexical cohesion and its subclasses, namely, repetition (same type, synonym, near-synonym, super-ordinate item, and general item and collocation. The corpus includes five argumentative essays written by students in the field of English language literature. Five teaching assistants were asked to rank the papers on a five-point scale based on their perception of the papers’ writing quality. The results showed that the paper that received the lowest rating in terms of the writing quality was the one that included the largest number of repetition occurrences of the same type. The study concludes by arguing that repetition may not be considered as monolithic, and suggests that every type of repetition needs to be examined individually in order to determine what enhances and what deteriorates the writing quality.

Slow stress relaxation behavior of cohesive powders

NARCIS (Netherlands)

Imole, Olukayode Isaiah; Paulick, Maria; Magnanimo, Vanessa; Morgenmeyer, Martin; Ramaioli, Marco; Chavez Montes, Bruno E.; Kwade, Arno; Luding, Stefan

2016-01-01

We present uniaxial (oedometric) compression tests on two cohesive industrially relevant granular materials (cocoa and limestone powder). A comprehensive set of experiments is performed using two devices – the FT4 Powder Rheometer and the custom made lambdameter – in order to investigate the

TERRITORIAL COHESION AND LOCAL DEVELOPMENT USING EUROPEAN STRUCTURAL AND COHESION FUNDS AT THE LEVEL OF GROWTH POLES – CASE STUDY GROWTH POLE BRASOV

Directory of Open Access Journals (Sweden)

Aida Petronela CATANA

2015-08-01

Full Text Available The growth poles were established in Romania in 2008 as centers for urban development in compliance with European and national policies and they include an urban nucleus and its rural surroundings.  According to the legal framework, for each of the growth poles an Integrated Development Plan should be adopted as basis for European Structural and Cohesion Funds investments. This is a new document in addition to local development plans/strategies of the local communities or counties and regional development plans. From another point of view, the growth poles are representing teritorial units which have to assure territorial cohesion for its urban and rural administrative units. Into this respect, there are different spatial planning documents which have to be followed by the territorial and administrative units, according to the Romanian legislation. Beyond these, there are rules and compulsory criterias for accessing European Structural and Cohesion funds the problems being faced by the associations established by local communities in order to manage the growth poles’s areas. Taking into account all these, we may say that growth poles are the crossing points for different policies translated into plans and operational programmes’s criterias for getting ESC Funds.

Determination of diffusion coefficients in cohesive and sandy sediment from the area of Gorleben

International Nuclear Information System (INIS)

Klotz, D.

1989-01-01

The cohesive and sandy sediments stem from shaft driving at the Gorleben salt done. For the cohesive materials, HTD was used as a tracer substance, while I-131 - was used for the sandy materials. Diffusion coefficients of HTD in cohesive materials in their natural texture are in the range of 2x10 -6 to 5x10 -6 cm 2 /s, those of I-131 - in the investigated uniform fine and middle sands are approximately 3x10 -6 cm 2 /s. (DG) [de

Neighborhood Social Cohesion and Sleep Outcomes in the Native Hawaiian and Pacific Islander National Health Interview Survey.

Science.gov (United States)

Young, Marielle C; Gerber, Monica W; Ash, Tayla; Horan, Christine M; Taveras, Elsie M

2018-05-16

Native Hawaiians and Pacific Islanders (NHPIs) have the lowest attainment of healthy sleep duration among all racial and ethnic groups in the United States. We examined associations of neighborhood social cohesion with sleep duration and quality. Cross-sectional analysis of 2,464 adults in the NHPI National Health Interview Survey (2014). Neighborhood social cohesion was categorized as a continuous and categorical variable into low (15) according to tertiles of the distribution of responses. We used multinomial logistic regression to examine the adjusted odds ratio of short and long sleep duration relative to intermediate sleep duration. We used binary logistic regression for dichotomous sleep quality outcomes. Sleep outcomes were modeled as categorical variables. 40% of the cohort reported short (9 hours) duration. Mean (SE, range) social cohesion score was 12.4 units (0.11, 4-16) and 23% reported low social cohesion. In multivariable models, each 1 SD decrease in neighborhood social cohesion score was associated with higher odds of short sleep duration (OR: 1.14, 95% CI: 1.02, 1.29). Additionally, low social cohesion was associated with increased odds of short sleep duration (OR: 1.53, 95% CI: 1.10, 2.13). No associations between neighborhood social cohesion and having trouble falling or staying asleep and feeling well rested were found. Low neighborhood social cohesion is associated with short sleep duration in NHPIs.

Social cohesion: solution or driver of urban violence?

International Development Research Centre (IDRC) Digital Library (Canada)

to the state intervention, eroding existing civil society organization. The presence of the police ... creating its own parallel structures to existing representative bodies, ... When designing interventions take into account that social cohesion may ...

Solidarity and Social Cohesion in Late Modernity

DEFF Research Database (Denmark)

Juul, Søren

2010-01-01

social cohesion. The central theme is that contemporary solidarity is about recognition and a fair distribution of chances for recognition. This ideal may function as a normative standard for critical research and as a guideline for people in their moral struggles. What ultimately needs to be done...

Cohesion, Flexibility, and the Mediating Effects of Shared Visionand Compassionon Engagement Army Acquisition Teams

Science.gov (United States)

2015-04-01

issues such as social desirability, negative affect, and acquiescence (Spector, 2006) in the analysis of final model. To test for multicollinearity ...emotional cohesion, cognitive cohesion, and flexibility) are independent with no multicollinearity issues. Development and test of structural

Influence of magnetic cohesion on the stability of granular slopes.

Science.gov (United States)

Taylor, K; King, P J; Swift, Michael R

2008-09-01

We use a molecular dynamics model to simulate the formation and evolution of a granular pile in two dimensions in order to gain a better understanding of the role of magnetic interactions in avalanche dynamics. We find that the angle of repose increases only slowly with magnetic field; the increase in angle is small even for intergrain cohesive forces many times stronger than gravity. The magnetic forces within the bulk of the pile partially cancel as a result of the anisotropic nature of the dipole-dipole interaction between grains. However, we show that this cancellation effect is not sufficiently strong to explain the discrepancy between the angle of repose in wet systems and magnetically cohesive systems. In our simulations we observe shearing deep within the pile, and we argue that it is this motion that prevents the angle of repose from increasing dramatically. We also investigate different implementations of friction with the front and back walls of the container, and conclude that the nature of the friction dramatically affects the influence of magnetic cohesion on the angle of repose.

A cohesive plastic/damage-zone model for ductile crack analysis

International Nuclear Information System (INIS)

Zhang, C.; Gross, D.

1995-01-01

A cohesive plastic/damage-zone model of the Dugdale-Barenblatt type (G.I. Barenblatt, Adv. Appl. Mech. 7 (1962) 55-129; D.S. Dugdale, J. Mech. Phys. Solids 8 (1960) 100-104) is presented for analyzing crack growth in ductile materials with damage evolution. A semi-infinite Mode I crack in plane stress or plane stress is considered. The damage is assumed to be present in form of dispersed microvoids which are localized into a narrow strip ahead of the crack-tip. A simple damage model of the Gurson model type (A.L. Gurson, J. Eng. Mater. Technol. 99 (1977) 2-15; V. Tvergaard, Advances in Applied Mechanics, Vol. 27, Academic Press, 1990, pp. 83-151) is developed for uniaxial tension to describe the macroscopic properties of the cohesive plastic/damage-zone. Under small-scale yielding and small-scale damage conditions, a system of nonlinear integral equations for the plastic strain and the length of the cohesive plastic/damage-zone is derived. Numerical results are presented and discussed to reveal the effect of damage evolution on the ductile crack growth. (orig.)

Bridge pier scour in cohesive soil: a review

Indian Academy of Sciences (India)

Y Sonia Devi

process and mechanism at bridge pier in cohesive and noncohesive soil are presented. The effects ... examples: one under laboratory condition and another under field condition. ..... not take part in scouring as these sediments are swept over.

Development and Application of a Cohesive Sediment Transport Model in Coastal Louisiana

Science.gov (United States)

Sorourian, S.; Nistor, I.

2017-12-01

The Louisiana coast has suffered from rapid land loss due to the combined effects of increasing the rate of eustatic sea level rise, insufficient riverine sediment input and subsidence. The sediment in this region is dominated by cohesive sediments (up to 80% of clay). This study presents a new model for calculating suspended sediment concentration (SSC) of cohesive sediments. Several new concepts are incorporated into the proposed model, which is capable of estimating the spatial and temporal variation in the concentration of cohesive sediment. First, the model incorporates the effect of electrochemical forces between cohesive sediment particles. Second, the wave friction factor is expressed in terms of the median particle size diameter in order to enhance the accuracy of the estimation of bed shear stress. Third, the erosion rate of cohesive sediments is also expressed in time-dependent form. Simulated SSC profiles are compared with field data collected from Vermilion Bay, Louisiana. The results of the proposed model agree well with the experimental data, as soon as steady state condition is achieved. The results of the new numerical models provide a better estimation of the suspended sediment concentration profile compared to the initial model developed by Mehta and Li, 2003. Among the proposed developments, the formulation of a time-dependent erosion rate shows the most accurate results. Coupling of present model with the Finite-Volume, primitive equation Community Ocean Model (FVCOM) would shed light on the fate of fine-grained sediments in order to increase overall retention and restoration of the Louisiana coastal plain.

Very low dose and dose-rate X-ray induced adaptive response in human lymphocytes at various cell cycle stages against bleomycin induced chromatid aberrations

International Nuclear Information System (INIS)

Hossein Mozdarani; Moghadam, R.N.

2007-01-01

Complete text of publication follows. Objective: To study the adaptive response induced by very low doses of X-rays at very low dose rate in human lymphocytes at different cell cycle stages followed by a challenge dose of bleomycin sulphate at G2 phase. Materials and Methods: Human peripheral blood lymphocytes before (G0) and after PHA stimulation (G1 and G2) were exposed to 1 and 5 cGy X-rays generated by a fluoroscopy unit with a dose rate of 5.56 mGy/min and challenged with 5 μg/ml bleomycin sulphate (BLM) 48 hours after culture initiation. Mitotic cells were arrested at metaphase by addition of colcemid in cultures 1.5 h before harvesting. Harvesting and slide preparation was performed using standard method. 100 well spread metaphases were analyzed for the presence of chromatid type aberrations for each sample. Results: Results obtained indicate that there is a linear relationship between the dose of BLM and chromatid aberrations below 5 μg/ml (R=0.93, p<0.0001). The results also show that pretreatment of lymphocytes with low dose X-rays at G0, G1 and G2 phases of the cell cycle significantly reduced the sensitivity of lymphocytes to the clastogenic effects of BLM in G2. Much lower frequencies of chromatid aberrations were observed in X-ray irradiated lymphocytes following BLM treatment (p<0.05). The magnitudes of adaptation induced at different phases of the cell cycle were not significantly different. Furthermore, there was no a significant difference in the magnitude of adaptive response induced by either 1 or 5 cGy X-rays. Conclusion: These observations might indicate that resistance of pre-exposure of lymphocytes to very low doses of X-rays protects them from clastogenic effects of BLM. This effect might be due to initial DNA damage induced in these cells leading to provocation of an active DNA repair mechanism independent of cell cycle stage.

EU COHESION POLICY NEEDS DIFFERENTIATED POLICY MIX ADEQUATE TO SPECIFICS OF ECONOMIC REGIONS

Directory of Open Access Journals (Sweden)

Gheorghe ZAMAN

2008-06-01

Full Text Available The 2007-2013 programming period of the EU focuses on economic and social cohesion via three fundamental objectives: convergence – competitiveness and employment – European territorial co-operation. The horizontal dimension of cohesion policy refers to diminishing the regional disparities and solidarity with the lagging regions’ population. Considering the big regional disparities in the New Member States (NMS as well as the gap between their GDP per capita at national level and the EU average, these countries are the main beneficiary of the EU financial allocations, especially via convergence objective. However, two interrelated questions are entailed by this issue. One of them refers to the capacity of these countries to absorb effectively the EU funds. The other one concentrates on the impact of the absorbed EU funds, in other words to the qualitative aspects of the absorption capacity. Our paper discusses these aspects mainly from the viewpoint of regional disparities in the NMS, proposing a typology of their regions based on the main regional growth characteristics. The implications of the structural assistance on regional disparities are also addressed, taking into consideration economic and social criteria and requirements at EU, national, regional and local levels.

Finite element analysis of an atomistically derived cohesive model for brittle fracture

International Nuclear Information System (INIS)

Lloyd, J T; McDowell, D L; Zimmerman, J A; Jones, R E; Zhou, X W

2011-01-01

In order to apply information from molecular dynamics (MD) simulations in problems governed by engineering length and time scales, a coarse graining methodology must be used. In previous work by Zhou et al (2009 Acta Mater. 57 4671–86), a traction-separation cohesive model was developed using results from MD simulations with atomistic-to-continuum measures of stress and displacement. Here, we implement this cohesive model within a combined finite element/cohesive surface element framework (referred to as a finite element approach or FEA), and examine the ability for the atomistically informed FEA to directly reproduce results from MD. We find that FEA shows close agreement of both stress and crack opening displacement profiles at the cohesive interface, although some differences do exist that can be attributed to the stochastic nature of finite temperature MD. The FEA methodology is then used to study slower loading rates that are computationally expensive for MD. We find that the crack growth process initially exhibits a rate-independent relationship between crack length and boundary displacement, followed by a rate-dependent regime where, at a given amount of boundary displacement, a lower applied strain rate produces a longer crack length. Our method is also extended to larger length scales by simulating a compact tension fracture-mechanics specimen with sub-micrometer dimensions. Such a simulation shows a computational speedup of approximately four orders of magnitude over conventional atomistic simulation, while exhibiting the expected fracture-mechanics response. Finally, differences between FEA and MD are explored with respect to ensemble and temperature effects in MD, and their impact on the cohesive model and crack growth behavior. These results enable us to make several recommendations to improve the methodology used to derive cohesive laws from MD simulations. In light of this work, which has critical implications for efforts to derive continuum laws

[Effects of Korean proficiency and parent-child cohesion on self-esteem and acculturation among children from multicultural families].

Science.gov (United States)

Kim, Mi Ye; Lim, Ji Young; Chung, Grace H

2012-12-01

There is evidence that parent-child cohesion is a potentially influential factor in children's self-esteem and acculturation. However, no research to date has examined cohesion with parents as a potential pathway between Korean proficiency and self-esteem or acculturation among children from multicultural families. This study was done to address these limitations by examining whether and to what extent cohesion with parents mediated the effect of Korean proficiency on self-esteem and acculturation among children from multicultural families. Data were collected from a sample of 138 mothers and their children living in Seoul, Daegu, Kyungi province, and Kyungpook province. Multiple regression analysis was used to examine the relationships between the variables of interest. Mediation effects of cohesion with parents were tested by following the procedure recommended by Baron and Kenny (1986). Cohesion with parents partially mediated the relationship between Korean proficiency and self-esteem. For children's acculturation, the effect of Korean proficiency was partially mediated through father-child cohesion. Mother-child cohesion completely mediated the relationship between Korean proficiency and acculturation. These findings suggest that to help children from multicultural families experiencing difficulties with self-esteem or acculturation, it might be useful to develop programs that are aimed at strengthen cohesion with parents.

Influence of dry cohesion on the micro- and macro-mechanical properties of dense polydisperse powders & grains

Science.gov (United States)

Kievitsbosch, Robert; Smit, Hendrik; Magnanimo, Vanessa; Luding, Stefan; Taghizadeh, Kianoosh

2017-06-01

Understanding how cohesive granular materials behave is of interest for many industrial applications, such as pharmaceutical or food and civil engineering. Models of the behaviour of granular materials on the microscopic scale can be used to obtain macroscopic continuum relations by a micro-macro transition approach. The Discrete Element Method (DEM) is used to inspect the influence of cohesion on the micro and macro behaviour of granular assemblies by using an elasto-plastic cohesive contact model. Interestingly, we observe that frictional samples prepared with different cohesion values show a significant difference in pressure and coordination number in the jammed regime; the differences become more pronounced when packings are closer to the jamming density, i.e. the lowest density where the system is mechanically stable. Furthermore, we observe that cohesion has an influence on the jamming density for frictional samples, but there is no influence on the jamming density for frictionless samples.

A season-long team-building intervention: examining the effect of team goal setting on cohesion.

Science.gov (United States)

Senécal, Julie; Loughead, Todd M; Bloom, Gordon A

2008-04-01

The purpose of the current study was to determine whether the implementation of a season-long team-building intervention program using team goal setting increased perceptions of cohesion. The participants were 86 female high school basketball players from 8 teams. The teams were randomly assigned to either an experimental team goal-setting or control condition. Each participant completed the Group Environment Questionnaire (GEQ; Carron, Brawley, & Widmeyer, 2002; Carron, Widmeyer, & Brawley, 1985), which assessed cohesion at both the beginning and end of the season. Overall, the results revealed a significant multivariate effect, Pillai's trace F(12, 438) = 2.68, p = .002. Post hoc analyses showed that at the beginning of the season, athletes from both conditions did not differ in their perceptions of cohesion. However, at the end of the season, athletes in the team goal-setting condition held higher perceptions of cohesion than athletes in the control condition. Overall, the results indicated that team goal setting was an effective team-building tool for influencing cohesiveness in sport teams.

Social cohesiveness and absenteeism: The relationship between characteristics of employees and short-term absenteeism

NARCIS (Netherlands)

Sanders, Karin; Nauta, Aukje

2004-01-01

This study tries to explain the relationship between characteristics of the employees (e.g., gender and working hours) and short-term absenteeism by examining the social cohesiveness of a team. Hypotheses are formulated concerning gender and working hours of employees, social cohesiveness, and

Great Expectations: How Role Expectations and Role Experiences Relate to Perceptions of Group Cohesion.

Science.gov (United States)

Benson, Alex J; Eys, Mark A; Irving, P Gregory

2016-04-01

Many athletes experience a discrepancy between the roles they expect to fulfill and the roles they eventually occupy. Drawing from met expectations theory, we applied response surface methodology to examine how role expectations, in relation to role experiences, influence perceptions of group cohesion among Canadian Interuniversity Sport athletes (N = 153). On the basis of data from two time points, as athletes approached and exceeded their role contribution expectations, they reported higher perceptions of task cohesion. Furthermore, as athletes approached and exceeded their social involvement expectations, they reported higher perceptions of social cohesion. These response surface patterns-pertaining to task and social cohesion-were driven by the positive influence of role experiences. On the basis of the interplay between athletes' role experiences and their perception of the group environment, efforts to improve team dynamics may benefit from focusing on improving the quality of role experiences, in conjunction with developing realistic role expectations.

On the application of cohesive crack modeling in cementitious materials

DEFF Research Database (Denmark)

Stang, Henrik; Olesen, John Forbes; Poulsen, Peter Noe

2007-01-01

typically for multi scale problems such as crack propagation in fiber reinforced composites. Mortar and concrete, however, are multi-scale materials and the question naturally arises, if bridged crack models in fact are more suitable for concrete and mortar as well? In trying to answer this question a model......Cohesive crack models-in particular the Fictitious Crack Model - are applied routinely in the analysis of crack propagation in concrete and mortar. Bridged crack models-where cohesive stresses are assumed to exist together with a stress singularity at the crack tip-on the other hand, are used...

ReaderBench: An Integrated Cohesion-Centered Framework

NARCIS (Netherlands)

Dascalu, Mihai; Stavarache, Lucia Larise; Dessus, Philippe; Trausan-Matu, Stefan; McNamara, Danielle S.; Bianco, Maryse

2015-01-01

Dascalu, M., Stavarache, L.L., Dessus, P., Trausan-Matu, S., McNamara, D.S., & Bianco, M. (2015). ReaderBench: An Integrated Cohesion-Centered Framework. In G. Conole, T. Klobucar, C. Rensing, J. Konert & É. Lavoué (Eds.), 10th European Conf. on Technology Enhanced Learning (pp. 505–508). Toledo,

Group Cohesiveness in the Black Panther Party

Science.gov (United States)

Calloway, Carolyn R.

1977-01-01

This study selects for study the following propositions: 1) similarity among members increased the degree of cohesiveness within the party, 2) group devotion heightened interest in accomplishing group goals and 3) the threat of an external enemy led to interdependence among members and affected both activities and leadership styles. (Author/AM)

Altruistic behavior in cohesive social groups: The role of target identifiability.

Science.gov (United States)

Ritov, Ilana; Kogut, Tehila

2017-01-01

People's tendency to be more generous toward identifiable victims than toward unidentifiable or statistical victims is known as the Identifiable Victim Effect. Recent research has called the generality of this effect into question, showing that in cross-national contexts, identifiability mostly affects willingness to help victims of one's own "in-group." Furthermore, in inter-group conflict situations, identifiability increased generosity toward a member of the adversary group, but decreased generosity toward a member of one's own group. In the present research we examine the role of group-cohesiveness as an underlying factor accounting for these divergent findings. In particular, we examined novel groups generated in the lab, using the minimal group paradigm, as well as natural groups of students in regular exercise sections. Allocation decisions in dictator games revealed that a group's cohesiveness affects generosity toward in-group and out-group recipients differently, depending on their identifiability. In particular, in cohesive groups the identification of an in-group recipient decreased, rather than increased generosity.

Altruistic behavior in cohesive social groups: The role of target identifiability.

Directory of Open Access Journals (Sweden)

Ilana Ritov

Full Text Available People's tendency to be more generous toward identifiable victims than toward unidentifiable or statistical victims is known as the Identifiable Victim Effect. Recent research has called the generality of this effect into question, showing that in cross-national contexts, identifiability mostly affects willingness to help victims of one's own "in-group." Furthermore, in inter-group conflict situations, identifiability increased generosity toward a member of the adversary group, but decreased generosity toward a member of one's own group. In the present research we examine the role of group-cohesiveness as an underlying factor accounting for these divergent findings. In particular, we examined novel groups generated in the lab, using the minimal group paradigm, as well as natural groups of students in regular exercise sections. Allocation decisions in dictator games revealed that a group's cohesiveness affects generosity toward in-group and out-group recipients differently, depending on their identifiability. In particular, in cohesive groups the identification of an in-group recipient decreased, rather than increased generosity.

Cohesive granular media modelization with non-convex particles shape: Application to UO2 powder compaction

International Nuclear Information System (INIS)

Saint-Cyr, B.

2011-01-01

We model in this work granular materials composed of non-convex and cohesive aggregates, in view of application to the rheology of UO 2 powders. The effect of non convexity is analyzed in terms of bulk quantities (Coulomb internal friction and cohesion) and micromechanical parameters such as texture anisotropy and force transmission. In particular, we find that the packing fraction evolves in a complex manner with the shape non convexity and the shear strength increases but saturates due to interlocking between the aggregates. We introduce simple models to describe these features in terms of micro-mechanical parameters. Furthermore, a systematic investigation of shearing, uniaxial compaction and simple compression of cohesive packings show that bulk cohesion increases with non-convexity but is strongly influenced by the boundary conditions and shear bands or stress concentration. (author) [fr

New Territorial Development Tools in the Cohesion Policy 2014-2020

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Györgyi Nyikos

2014-12-01

Full Text Available Nowadays an important question is how to use the limited resources available in the most efficient and sustainable way. The assessment of development policy interventions and the question of successful absorption of development funds shifted clearly towards stronger enforcement of the aspects efficiency and effectiveness. There is clearly a need for an integrated approach to deliver an effective and sustainable response. The question is how the new territorial development tools – established by the new cohesion policy regulation for the coming programming period - can fit in these conditions, how can they help to achieve the common goals and response to the integrated approach. Cooperation and in-depth knowledge is required for stakeholders to make use of the new tools in an integrated manner.

Validation of the Child Sport Cohesion Questionnaire

Science.gov (United States)

Martin, Luc J.; Carron, Albert V.; Eys, Mark A.; Loughead, Todd

2013-01-01

The purpose of the present study was to test the validity evidence of the Child Sport Cohesion Questionnaire (CSCQ). To accomplish this task, convergent, discriminant, and known-group difference validity were examined, along with factorial validity via confirmatory factor analysis (CFA). Child athletes (N = 290, M[subscript age] = 10.73 plus or…

Parent-child cohesion, friend companionship and left-behind children's emotional adaptation in rural China.

Science.gov (United States)

Zhao, Jingxin; Liu, Xia; Wang, Meifang

2015-10-01

Using cross-sectional data from rural left-behind children aged 10-17 years in the Henan Province of China, the present study examined the roles of father-child cohesion, mother-child cohesion, and friend companionship in emotional adaptation (loneliness, depression, and life satisfaction) among children left behind by both of their rural-to-urban migrant parents compared to those with only a migrating father. The results indicated that the children with two migrating parents were disadvantaged according to their demonstration of depression but not in loneliness or life satisfaction. Both parent-child cohesion and friend companionship were directly associated with, to varying extents, the left-behind children's emotional outcomes. Moreover, friend companionship moderated the association between father-child cohesion and emotional outcomes among children with two migrating parents, but the moderating effects of friend companionship did not exist among children with only a migrating father. The implications of these findings for interventions directed at left-behind children are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

DEVELOPMENT OF REGIONS AND MUNICIPALITIES OF THE SLOVAK REPUBLIC BY APPLICATION OF EUROPEAN COHESION POLICY

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Katarina Rentkova

2017-03-01

Full Text Available The Slovak republic, entering the European Union on the 1st May 2004, got the impulse on the improvement and growth also via the application of the Cohesion policy. For the programming period 2007-2013, the amount of 11.3 milliards Euros for the application of the Cohesion policy have been provided to the Slovak republic. In the present time, the programming period is finished and the Slovak republic meets the critical reviews in the area of the effective use and maintenance of projects and application of the Cohesion policy on its territory. Many specialists, economists and analysts try to reveal the errors, identify the subjects that enter into the project cycle wrongly or to identify the bodies that have the most important influence on the low level of the financial instruments use and they also try to deal with the criticism of the European Commission as to the project realization. From this point of view, the theme of the research is very actual and imperative because the research tries to enlighten and to analyze the application of the cohesion policy within the territory of the Slovak republic and so, to state recommendations for more effective application for the following programming period. The article is created by analyzing the application of the European cohesion policy in the programming period 2007 - 2013 in the Slovak Republic. The main objective of the article is to analyze and define the cohesion policy of the European Union and one of the partial objectives is to execute the analysis on the implementation state of the Cohesion policy on the level of the chosen regions in the Slovak republic and then, to propose and to create recommendations and techniques for its effective functioning.

Moralized Health-Related Persuasion Undermines Social Cohesion

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Susanne Täuber

2018-06-01

Full Text Available Integrating theory and research on persuasion, moralization, and intergroup relations, the present research aims to highlight the far-reaching impact of health-related persuasion on society. I propose that governments’ health-related persuasion leads to the emergence of new social norms, and in particular moral norms. Importantly, moral norms provide strong behavioral imperatives and are seen as binding for group members. This suggests that moralized persuasion has a strong potential to divide society along the lines of citizens who conform to and citizens who deviate from health-related moral norms. Thus, departing from the traditional focus on targets of persuasion, the present research focuses on those holding a moralized view on health and lifestyle. Key aspects of social cohesion as defined by the OECD (2011 have been tested across four studies. The main hypothesis tested is that those conforming to the norm (e.g., non-smokers, normal weight people, people with healthy lifestyles will stigmatize those deviating from the norm (e.g., smokers, overweight people, people with unhealthy lifestyles. Flowing from stigmatization, less inclusion, lower solidarity with and greater endorsement of unequal treatment of those deviating from the moral norm are predicted. Four survey studies (total N = 1568 examining the proposed associations among non-smokers, normal weight people, and employees with healthy lifestyles are presented. The studies provide unanimous support for the hypothesis, with meta-analysis providing further support for the reliability of the findings. Consistent across studies, social cohesion indicators were negatively affected by health moralization through stigmatization of those deviating from health-related moral norms. Findings highlight an under-acknowledged potential of moralized health-related persuasion to divide society, thereby undermining cohesion and the achievement of important societal goals. In the discussion

Working with Group-Tasks and Group Cohesiveness

Science.gov (United States)

Anwar, Khoirul

2016-01-01

This study aimed at exploring the connection between the use of group task and group cohesiveness. This study is very important because the nature of the learner's success is largely determined by the values of cooperation, interaction, and understanding of the learning objectives together. Subjects of this study are 28 students on the course…

FUNDING COHESION POLICY IN THE EUROPEAN UNION AND ROMANIA DURING 2014 – 2020

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MARIA VASILESCU

2016-08-01

Full Text Available Cohesion policy is one of the most important and complex policy of the European Union, a position clearly derived from the assumed objective of "harmonious development by reducing disparities between the levels of development of the various regions and the backwardness of the least favoured regions or islands". Its unique role in shaping and implementing integrated development strategies, which involve activities in various fields such as education, research and innovation, employment, business environment, infrastructure, environmental protection, climate change and energy efficiency is undeniable. To accomplish these goals cohesion policy is benefiting from its own budget for each Member State in relation to the national objectives of economic and social development and to integration into the Single Internal Market and achieving territorial cohesion

Grain boundary embrittlement and cohesion enhancement in copper

Energy Technology Data Exchange (ETDEWEB)

Paxton, Anthony; Lozovoi, Alexander [Atomistic Simulation Centre, Queen' s University Belfast, BT7 1NN (United Kingdom); Schweinfest, Rainer [Science+Computing ag, Hagellocher Weg 71-5, 720270 T ubingen (Germany); Finnis, Michael [Imperial College London, Exhibition Road, London SW7 2AZ (United Kingdom)

2008-07-01

There has been a long standing debate surrounding the mechanism of grain boundary embrittlement and cohesion enhancement in metals. Embrittlement can lead to catastrophic failure such as happened in the Hinkley Point disaster, or indeed in the case of the Titanic. This kind of embrittlement is caused by segregation of low solubility impurities to grain boundaries. While the accepted wisdom is that this is a phenomenon driven by electronic or chemical factors, using language such as charge transfer and electronegativity difference; we believe that in copper, at least, both cohesion enhancement and reduction are caused by a simple size effect. We have developed a theory that allows us to separate unambiguously, if not uniquely, chemical and structural factors. We have studied a large number of solutes in copper using first principles atomistic simulation to support this argument, and the results of these calculations are presented here.

"Sticking Together": The Adolescent Experience of the Cohesion Process in Rural School Counseling Groups

Science.gov (United States)

Gray, Tara M.; Rubel, Deborah

2018-01-01

The purpose of this study was to develop a grounded theory of how adolescents experience the cohesion process in rural school counseling groups. A total of 20 individual interviews with 7 participants were conducted. Data analysis generated the central category of the cohesion process as "sticking together," which describes a "tight…

Sense of belonging and social cohesion in a desegregated former House of Delegates school

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Ramodungoane Tabane

2010-01-01

Full Text Available The ideal of creating a non-racial and equitable school environment is embedded in the South African Constitution. This ideal is informed by a desire to overcome the divisions of the apartheid past by pursuing policies and strategies that will promote the achievement of social cohesion, without denying space for various identities. Schools are seen as important vehicles for driving social cohesion amongst learners and it is therefore important that all learners, irrespective of their race, experience a sense of belonging in the school. Using a case study and an interactive qualitative analysis research methodology, we explored the experiences of black and Indian learners in a desegregated former House of Delegates school to determine the successes and possible challenges of ensuring racial integration at the school level and therefore its contribution to social cohesion. The study demonstrates the importance of eight concepts (namely, the school as a welcoming space; belonging; respect; security; equality in the way we socialise; tender loving care; motivation; and freedom to the study of racial integration and social cohesion. This article focuses on the contribution that sense of belonging has on creating a school environment that is enabling, contributing to learner achievement and concludes that sense of belonging, integration, and social cohesion are intertwined and important in creating an environment that is welcoming and a "home" to diverse learners and educators.

Natural disasters and indicators of social cohesion

Czech Academy of Sciences Publication Activity Database

Calo-Blanco, A.; Kovářík, Jaromír; Mengel, F.; Romero, J. G.

2017-01-01

Roč. 12, č. 6 (2017), s. 1-13, č. článku e0176885. E-ISSN 1932-6203 R&D Projects: GA ČR(CZ) GA14-22044S Institutional support: RVO:67985998 Keywords : social cohesion * trust * climate Subject RIV: AH - Economic s OBOR OECD: Applied Economic s, Econometrics Impact factor: 2.806, year: 2016

Toward a Cohesive Theory of Visual Literacy

Science.gov (United States)

Avgerinou, Maria D.; Pettersson, Rune

2011-01-01

Despite the fact that to date Visual Literacy (VL) scholars have not arrived at a general consensus for a theoretical organization of the VL field, important conceptual investigations have emerged over the past four decades. In this paper we discuss and synthesize those studies. We then present a first attempt toward a cohesive theory of VL. The…

Effect of softening function on the cohesive crack fracture ...

Indian Academy of Sciences (India)

The cohesive crack model with linear softening yields the fracture process zones lower by ..... ignored during numerical simulation. In the crack band ..... performed with developed computer program using MATLAB for the following numerical.

Group cohesion and social support of the nurses in a special unit and a general unit in Korea.

Science.gov (United States)

Ko, Yu Kyung

2011-07-01

To identify the degree of group cohesion and social support of nurses in special and general units in hospitals in Korea, and to compare group cohesion and social support between the two groups. The level of commitment nurses have to their organizations has been shown to correlate with work group cohesion and social support. The participants were 1751 nurses who were working in Korean hospitals. Data were collected using a structured questionnaire and were analysed using SAS. The statistical methods included: descriptive statistics, t-test, anova and Pearson's correlation coefficients. Group cohesion of nurses on special wards was significantly higher than for nurses on general wards. No significant difference was found between types of units in terms of social support. The degree of group cohesion was significantly different in terms of the respondents' clinical experience, position, religion, job satisfaction, number of supportive superiors and number of supportive peers. A statistically significant correlation was found between group cohesion scores and degree of social support. Hospital management can accomplish their goals more effectively through knowledge of the level of group cohesion, superior support and peer support for nursing staff in accordance with unit specialty. © 2011 The Author. Journal compilation © 2011 Blackwell Publishing Ltd.

Molecular-dynamics Simulation-based Cohesive Zone Representation of Intergranular Fracture Processes in Aluminum

Science.gov (United States)

Yamakov, Vesselin I.; Saether, Erik; Phillips, Dawn R.; Glaessgen, Edward H.

2006-01-01

A traction-displacement relationship that may be embedded into a cohesive zone model for microscale problems of intergranular fracture is extracted from atomistic molecular-dynamics simulations. A molecular-dynamics model for crack propagation under steady-state conditions is developed to analyze intergranular fracture along a flat 99 [1 1 0] symmetric tilt grain boundary in aluminum. Under hydrostatic tensile load, the simulation reveals asymmetric crack propagation in the two opposite directions along the grain boundary. In one direction, the crack propagates in a brittle manner by cleavage with very little or no dislocation emission, and in the other direction, the propagation is ductile through the mechanism of deformation twinning. This behavior is consistent with the Rice criterion for cleavage vs. dislocation blunting transition at the crack tip. The preference for twinning to dislocation slip is in agreement with the predictions of the Tadmor and Hai criterion. A comparison with finite element calculations shows that while the stress field around the brittle crack tip follows the expected elastic solution for the given boundary conditions of the model, the stress field around the twinning crack tip has a strong plastic contribution. Through the definition of a Cohesive-Zone-Volume-Element an atomistic analog to a continuum cohesive zone model element - the results from the molecular-dynamics simulation are recast to obtain an average continuum traction-displacement relationship to represent cohesive zone interaction along a characteristic length of the grain boundary interface for the cases of ductile and brittle decohesion. Keywords: Crack-tip plasticity; Cohesive zone model; Grain boundary decohesion; Intergranular fracture; Molecular-dynamics simulation

Measuring the impact of spatial network layout on community social cohesion: a cross-sectional study.

Science.gov (United States)

Cooper, Crispin H V; Fone, David L; Chiaradia, Alain J F

2014-04-11

There is now a substantial body of research suggesting that social cohesion, a collective characteristic measured by the levels of trust, reciprocity and formation of strong social bonds within communities, is an important factor in determining health. Of particular interest is the extent to which factors in the built environment facilitate, or impede, the development of social bonds. Severance is a characteristic of physical environments which is hypothesized to inhibit cohesion. In the current study we test a number of characteristics of spatial networks which could be hypothesized to relate either to severance, or directly to community cohesion. Particular focus is given to our most promising variable for further analysis (Convex Hull Maximum Radius 600 m). In the current study we analysed social cohesion as measured at Enumeration District level, aggregated from a survey of 10,892 individuals aged 18 to 74 years in the Caerphilly Health and Social Needs Cohort Study, 2001. In a data mining process we test 16 network variables on multiple scales. The variable showing the most promise is validated in a test on an independent data set. We then conduct a multivariate regression also including Townsend deprivation scores and urban/rural status as predictor variables for social cohesion. We find convex hull maximum radius at a 600 m scale to have a small but highly significant correlation with social cohesion on both data sets. Deprivation has a stronger effect. Splitting the analysis by tertile of deprivation, we find that the effect of severance as measured by this variable is strongest in the most deprived areas. A range of spatial scales are tested, with the strongest effects being observed at scales that match typical walking distances. We conclude that physical connectivity as measured in this paper has a significant effect on social cohesion, and that our measure is unlikely to proxy either deprivation or the urban/rural status of communities. Possible

Appraisal in a Team Context: Perceptions of Cohesion Predict Competition Importance and Prospects for Coping.

Science.gov (United States)

Wolf, Svenja A; Eys, Mark A; Sadler, Pamela; Kleinert, Jens

2015-10-01

Athletes' precompetitive appraisal is important because it determines emotions, which may impact performance. When part of a team, athletes make their appraisal within a social context, and in this study we examined whether perceived team cohesion, as a characteristic of this context, related to appraisal. We asked 386 male and female intercollegiate team-sport athletes to respond to measures of cohesion and precompetitive appraisal before an in-season game. For males and females, across all teams, (a) an appraisal of increased competition importance was predicted by perceptions of higher task cohesion (individual level), better previous team performance, and a weaker opponent (team level) and (b) an appraisal of more positive prospects for coping with competitive demands was predicted by higher individual attractions to the group (individual level). Consequently, athletes who perceive their team as more cohesive likely appraise the pending competition as a challenge, which would benefit both emotions and performance.

The variability of root cohesion as an influence on shallow landslide susceptibility in the Oregon Coast Range

Science.gov (United States)

Schmidt, K.M.; Roering, J.J.; Stock, J.D.; Dietrich, W.E.; Montgomery, D.R.; Schaub, T.

2001-01-01

Decades of quantitative measurement indicate that roots can mechanically reinforce shallow soils in forested landscapes. Forests, however, have variations in vegetation species and age which can dominate the local stability of landslide-initiation sites. To assess the influence of this variability on root cohesion we examined scarps of landslides triggered during large storms in February and November of 1996 in the Oregon Coast Range and hand-dug soil pits on stable ground. At 41 sites we estimated the cohesive reinforcement to soil due to roots by determining the tensile strength, species, depth, orientation, relative health, and the density of roots ???1 mm in diameter within a measured soil area. We found that median lateral root cohesion ranges from 6.8-23.2 kPa in industrial forests with significant understory and deciduous vegetation to 25.6-94.3 kPa in natural forests dominated by coniferous vegetation. Lateral root cohesion in clearcuts is uniformly ???10 kPa. Some 100-year-old industrial forests have species compositions, lateral root cohesion, and root diameters that more closely resemble 10-year-old clearcuts than natural forests. As such, the influence of root cohesion variability on landslide susceptibility cannot be determined solely from broad age classifications or extrapolated from the presence of one species of vegetation. Furthermore, the anthropogenic disturbance legacy modifies root cohesion for at least a century and should be considered when comparing contemporary landslide rates from industrial forests with geologic background rates.

A prospective study of group cohesiveness in therapeutic horticulture for clinical depression.

Science.gov (United States)

Gonzalez, Marianne Thorsen; Hartig, Terry; Patil, Grete Grindal; Martinsen, Egil W; Kirkevold, Marit

2011-04-01

This study aimed to assess changes in psychological distress and social participation in adults diagnosed with clinical depression during and after participating in a therapeutic horticulture programme, and to investigate if the changes covaried with levels of group cohesiveness during the intervention. An intervention with a single-group design was repeated with different samples in successive years (pooled n = 46). In each year, five groups of 3-7 participants went through the intervention. Data were collected before, twice during, and immediately after a 12-week therapeutic horticulture programme, as well as at 3-months' follow up. Mental health assessments included the Beck Depression Inventory, the State Subscale of Spielberger State-Trait Anxiety Inventory, the Positive Affect Scale from the Positive and Negative Affect Scale, the Perceived Stress Scale, and the Therapeutic Factors Inventory-Cohesiveness Scale. The analysis of the pooled data confirmed significant beneficial change in all mental health variables during the intervention. Change from baseline in depression severity persisted at 3-months' follow up. Increased social activity after the intervention was reported for 38% of the participants. The groups quickly established strong cohesiveness, and this continued to increase during the intervention. The average level of group cohesiveness correlated positively, but not significantly, with change in all mental health outcome variables. © 2011 The Authors. International Journal of Mental Health Nursing © 2011 Australian College of Mental Health Nurses Inc.

Investigation on the cohesive silt/clay-particle sediment via the coupled CFD-DEM simulations

Science.gov (United States)

Xu, S.; Sun, H.; Sun, R.

2017-12-01

Sedimentation of silt/clay particles happens ubiquitously in nature and engineering field. There have been abundant studies focusing on the settling velocity of the cohesive particles, while studies on the sediment deposited from silt/clay irregular particles, including the vertical concentration profile of sediment and the various forces among the deposited particles are still lacking. This paper aims to investigate the above topics by employing the CFD-DEM (Computational Fluid Dynamics-Discrete Element Method) simulations. In this work, we simulate the settling of the mono- and poly- dispersed silt/clay particles and mainly study the characteristics of the deposited cohesive sediment. We use the bonded particles to simulate the irregular silt/clay aggregates at the initial state and utilize the van der Waals force for all micro-particles to consider the cohesive force among silt/clay particles. The interparticle collision force and the fluid-particle interaction forces are also considered in our numerical model. The value of the mean structural density of cohesive sediment obtained from simulations is in good agreement with the previous research, and it is obviously smaller than no-cohesive sediment because of the existence of the silt/clay flocs. Moreover, the solid concentration of sediment increases with the growth of the depth. It is because the silt/clay flocs are more easily to break up due to the gradually increased submerged gravity of the deposited particles along the depth. We also obtain the noncontacted cohesive force and contact force profiles during the sedimentation and the self-weight consolidation process. The study of the concentration profile and the forces among silt/clay sediment will help to give an accurate initial condition for calculating the speed of the reconsolidation process by employing the artificial loads, which is necessary for practical designs of the land reclamation projects.

Family Change and Implications for Family Solidarity and Social Cohesion

Directory of Open Access Journals (Sweden)

Ravanera, Zenaida

2008-01-01

Full Text Available EnglishSocial cohesion can be viewed in terms of common projects and networks of social relations that characterize families, communities and society. In the past decades, the basis for family cohesion has shifted from organic to mechanical or from breadwinner to collaborative model. As in many Western countries, data on family change in Canada point to a greater flexibility in the entry and exit from relationships, a delay in the timing of family events, and a diversity of family forms. After looking at changes in families and in the family setting of individuals, the paper considers both intra-family cohesion and families as basis for social cohesion. Implications are raised for adults, children and publicp olicy.FrenchLa cohésion sociale peut se voir à travers les projets communs et les réseaux desrelations sociales qui caractérisent les familles, les communautés et les sociétés.La base de cohésion familiale est passée d’organique à mécanique, pour utiliserles termes de Durkheim, ou vers un modèle de collaboration plutôt qu’unepartage asymétrique de tâches. Comme dans d’autres sociétés orientales, lafamille au Canada est devenue plus flexible par rapport aux entrées et sortiesd’unions, il y a un délais dans les événements familiaux, et une variété deformes de familles. Après un regard sur les changements dans les familles etdans la situation familiale des individus, nous considérons la cohésion intrafamilialeet la famille comme base de cohésion sociale. Nous discutons desimpacts sur les adultes, les enfants et la politique publique.

Factors associated with low neighborhood cohesion among women living with HIV impacted by social-structural inequities in British Columbia.

Science.gov (United States)

Closson, Kalysha; Palmer, Alexis K; Collins, Alexandra B; Salters, Kate; Zhang, Wendy; Montaner, Julio S G; Hogg, Robert S; Parashar, Surita

2018-03-01

Built and social environments, including one's perception of their environment, are important determinants of health. The intersection of gender and HIV status may complicate the role of neighborhood cohesion in safety, personal well-being, and health outcomes for populations impacted by social and structural inequities. Among women in particular, social cohesion within the neighborhood they reside in may have a greater influence on health outcomes compared to their male counterparts. We sought to examine perception of neighborhood cohesion (validated scale with a range 0-100, with higher scores indicating higher perceived neighborhood cohesion) among women living with HIV, impacted by social-structural inequities, receiving combination antiretroviral therapy, and enrolled in the Longitudinal Investigations into Supportive Ancillary health services (LISA) study in British Columbia, Canada. Cross-sectional data on neighborhood cohesion and socio-demographic data were collected in an interviewer-administered survey. Of the 1,000 LISA participants interviewed, 908 (including 249 women and 659 men) had complete data for the variables of interest. At the bivariate level, women had worse perceived neighborhood cohesion scores compared to men (median: 56 [95% CI: 44-66] vs. 60 [95% CI: 47-71]). Multivariable model results indicated that for women living with HIV in our sample, greater neighborhood cohesion scores were positively associated with stable housing (β coefficient = 7.85; 95% CI: 3.61, 12.10, p perceptions of neighborhood cohesion.

Very low sister-chromatid exchange rate in Seventh-Day Adventists.

Science.gov (United States)

Wulf, H C; Iversen, A S; Husum, B; Niebuhr, E

1986-08-01

42 Seventh-Day Adventists (SDAs) and 42 controls matched for sex, age and occupation had their sister-chromatid exchange (SCE) examined in peripheral blood lymphocytes. This was done to examine if the SCE frequency was lower in this group of people, who are known to have a decreased cancer risk compared to the general population. The average SCE/cell in 30 cells from each person was 5.54 +/- 0.07 (mean +/- standard error of the mean) for the SDAs and 8.00 +/- 0.15 for the controls, the difference being statistically significant (p less than 0.00001). No difference in SCE frequency was found between SDAs eating only an ovo-lacto-vegetarian diet and those eating some fish or meat. The mitotic index (MI) was significantly higher and the replication index (RI) was significantly lower in SDAs than in controls. No correlation was found between gamma (a statistical transformation of SCEs/cell) and MI or RI within the groups of SDAs or controls. In the pooled data there was a negative correlation of gamma and MI and a positive correlation of gamma and RI. Of the interpersonal variation in gamma 8% and 14% could be explained by MI and RI. The finding of a lower SCE frequency in a group of SDAs who have a low risk of cancer might indirectly indicate a relation between SCE and cancer and encourages further studies of SCE and diet.

The Role of Preceptorship and Group Cohesion on Newly Licensed Registered Nurses' Satisfaction and Intent to Stay.

Science.gov (United States)

Bontrager, Sarah; Hart, Patricia L; Mareno, Nicole

2016-03-01

Thirteen percent of newly licensed registered nurses (NLRNs) vacate their first job after 1 year, and 37% report that they feel ready to change jobs. Turnover can lead to consistent and detrimental nursing shortages in nursing units, as well as increased costs for health care systems. A descriptive, prospective, cross-sectional design was used to understand how preceptor role effectiveness and group cohesion affect NLRNs' satisfaction and intent to stay. NLRNs reported high levels of perceived preceptor role effectiveness, group cohesion, and job satisfaction, with only moderate levels of intent to stay. Statistically significant relationships were found among preceptor role effectiveness, job satisfaction, and intent to stay, as well as among group cohesion, job satisfaction, and intent to stay. Preceptor role effectiveness and group cohesion are predictors of NLRNs' level of job satisfaction. Job satisfaction is a predictor of NLRNs' intent to stay. Effective preceptors and positive group cohesion are factors that are important to NLRNs' job satisfaction and intent to stay. Copyright 2016, SLACK Incorporated.

Team cohesion in intensive care nursing: at the interface of nurse self-concept and unit structure

DEFF Research Database (Denmark)

Paunova, Minna; Li-Ying, Jason

2017-01-01

Team cohesion is a critical factor in the provision of high-quality care, yet its antecedents remain understudied, particularly in the context of some healthcare professional groups where structural and individual constraints coexist, and demand for high quality performance is prevailing. In this......Team cohesion is a critical factor in the provision of high-quality care, yet its antecedents remain understudied, particularly in the context of some healthcare professional groups where structural and individual constraints coexist, and demand for high quality performance is prevailing...... their teams as cohesive. A multi-source and multi-level study of approximately 140 nurses employed in 20 ICUs across Denmark demonstrates the critical role of self-concept in easing and enhancing the constraints workplaces impose on team cohesion. Furthermore, the study confirms the positive relationship...

Perceptions of communication, family adaptability and cohesion: a comparison of adolescents newly diagnosed with cancer and their parents.

Science.gov (United States)

Phillips-Salimi, Celeste R; Robb, Sheri L; Monahan, Patrick O; Dossey, Amy; Haase, Joan E

2014-01-01

To describe and compare adolescent and parent perspectives on communication, family adaptability and cohesion, as well as relationships among these variables, during the first month of an adolescent's cancer diagnosis. Seventy adolescent-parent dyads were enrolled as part of a larger multi-site study. The adolescents ranged in age from 11 to 19, and 61% were males. Parents were predominately mothers (83%). Dyads were predominately non-Hispanic Caucasian (63%). Measures included the Parent-Adolescent Communication Scale and the Family Adaptability and Cohesion Evaluation Scale (FACES II). Paired t-tests, Pearson correlations, intra-class correlation coefficients and multiple linear regression analyses were completed. Adolescent scores on communication, family adaptability and cohesion were significantly lower than parent scores. The inter-dyadic agreement between adolescents and parents was low. Communication, family adaptability and cohesion were examined separately for adolescents and for parents, and significant relationships were found. Both adolescent- and parent-perceived communication was significantly associated with family adaptability and cohesion outcomes. Differences were found in adolescent and parent perceptions of communication, family adaptability and cohesion. When both adolescents and parents had better perceived communication, this was associated with better perceived family adaptability and cohesion. Results suggest that the development of interventions to enhance adolescent-parent communication could help foster better family adaptability and cohesion, which may ultimately impact their psychological adjustment. In addition, understanding the degree to which adolescents and parents disagree on their perceptions, including the results that parents generally have more favorable perceptions, may be a useful starting point when developing interventions.

Interdependence and organizational citizenship behavior: exploring the mediating effect of group cohesion in multilevel analysis.

Science.gov (United States)

Chen, Chun-Hsi Vivian; Tang, Ya-Yun; Wang, Shih-Jon

2009-12-01

The authors investigated the mechanism of group cohesion in the relationship between (a) task interdependence and goal interdependence and (b) individuals' organizational citizenship behavior (OCB). The authors adopted a multilevel perspective to facilitate understanding of the complex relations among variables. They collected data from 53 supervisors and 270 employees from R&D departments in Taiwan. The authors found that group cohesion fully mediated the effects of task interdependence and goal interdependence on employees' OCB. In addition, task interdependence had a greater effect on group cohesion than did goal interdependence. The authors discuss implications and suggestions for future research.

Social cohesion: solution or driver of urban violence? | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

2016-09-28

Sep 28, 2016 ... Social cohesion can play an important role in building and maintaining ... Analysis of Violence demonstrates how social bonds and stark inequalities can also play ... Conflict and development in the hill settlements of Guwahati.

Cohesive traction-separation relations for plate tearing under mixed mode loading

DEFF Research Database (Denmark)

Andersen, R. G.; Woelke, P. B.; Nielsen, K. L.

2018-01-01

The present study investigates a sequence of failure events related to steady-state tearing of large-scale ductile plates by employing the micro-mechanics based Gurson-Tvergaard-Needleman (GTN) model. The fracture process in front of an advancing crack is approximated by a series of 2D plane strain...... finite element models to facilitate a comprehensive study of mixed mode fracture behavior as well as a parameter study of the cohesive energy and tractions involved in the process. The results from the conducted GTN model simulations are used to define cohesive zone models suitable for plate tearing...

Relationship between Family Adaptability, Cohesion and Adolescent Problem Behaviors: Curvilinearity of Circumplex Model

OpenAIRE

Joh, Ju Youn; Kim, Sun; Park, Jun Li; Kim, Yeon Pyo

2013-01-01

Background The Family Adaptability and Cohesion Evaluation Scale (FACES) III using the circumplex model has been widely used in investigating family function. However, the criticism of the curvilinear hypothesis of the circumplex model has always been from an empirical point of view. This study examined the relationship between adolescent adaptability, cohesion, and adolescent problem behaviors, and especially testing the consistency of the curvilinear hypotheses with FACES III. Methods We us...

Examining the relationship between family meal frequency and individual dietary intake: does family cohesion play a role?

Science.gov (United States)

Welsh, Ericka M; French, Simone A; Wall, Melanie

2011-01-01

To confirm previously reported associations between family meal frequency and dietary intake, and to examine family cohesion as a potential mediator of this relationship. Cross-sectional observational study. Data collected at baseline via questionnaire. Randomized, controlled household weight gain prevention trial. Participants were 152 adults and 75 adolescents from 90 community households. Family meal frequency assessed with a single question. Perceived family cohesion measured by the Family Adaptability and Cohesion Evaluation Scale-III. Usual intake of targeted food items assessed with modified food frequency questionnaire. Hierarchical linear regression with mediation analysis. Statistical significance set at α-level .05. Family meal frequency was associated with intake of fruits and vegetables in adults, and sweets and sugar-sweetened beverages in adolescents. Family meal frequency was positively correlated with perceived family cohesion (r = 0.41, P family cohesion was observed for family meal frequency and sweets intake in adolescents. Results suggest that family cohesion is not a consistent mediator of relationship between family meal frequency and individual dietary intake. Future studies should assess additional plausible mediators of this relationship in order to better understand the effect of family meals on dietary intake. Copyright © 2011 Society for Nutrition Education. Published by Elsevier Inc. All rights reserved.

Cohesive subgroup formation : enabling and constraining effects of social capital in strategic technology alliance networks

NARCIS (Netherlands)

Duysters, G.M.; Lemmens, C.E.A.V.

2002-01-01

In this paper we will examine the role of embeddedness and social capital in the process of cohesive subgroup formation in strategic technology alliance networks. More in particular, we will investigate the social mechanisms that enable and enforce cohesive subgroup formation. We will argue that the

Absence of SUN-domain protein Slp1 blocks karyogamy and switches meiotic recombination and synapsis from homologs to sister chromatids

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Vasnier, Christelle; de Muyt, Arnaud; Zhang, Liangran; Tessé, Sophie; Kleckner, Nancy E.; Zickler, Denise; Espagne, Eric

2014-01-01

Karyogamy, the process of nuclear fusion is required for two haploid gamete nuclei to form a zygote. Also, in haplobiontic organisms, karyogamy is required to produce the diploid nucleus/cell that then enters meiosis. We identify sun like protein 1 (Slp1), member of the mid–Sad1p, UNC-84–domain ubiquitous family, as essential for karyogamy in the filamentous fungus Sordaria macrospora, thus uncovering a new function for this protein family. Slp1 is required at the last step, nuclear fusion, not for earlier events including nuclear movements, recognition, and juxtaposition. Correspondingly, like other family members, Slp1 localizes to the endoplasmic reticulum and also to its extensions comprising the nuclear envelope. Remarkably, despite the absence of nuclear fusion in the slp1 null mutant, meiosis proceeds efficiently in the two haploid “twin” nuclei, by the same program and timing as in diploid nuclei with a single dramatic exception: the normal prophase program of recombination and synapsis between homologous chromosomes, including loading of recombination and synaptonemal complex proteins, occurs instead between sister chromatids. Moreover, the numbers of recombination-initiating double-strand breaks (DSBs) and ensuing recombinational interactions, including foci of the essential crossover factor Homo sapiens enhancer of invasion 10 (Hei10), occur at half the diploid level in each haploid nucleus, implying per-chromosome specification of DSB formation. Further, the distribution of Hei10 foci shows interference like in diploid meiosis. Centromere and spindle dynamics, however, still occur in the diploid mode during the two meiotic divisions. These observations imply that the prophase program senses absence of karyogamy and/or absence of a homolog partner and adjusts the interchromosomal interaction program accordingly. PMID:25210014

Utilization of Large Cohesive Interface Elements for Delamination Simulation

DEFF Research Database (Denmark)

Bak, Brian Lau Verndal; Lund, Erik

2012-01-01

This paper describes the difficulties of utilizing large interface elements in delamination simulation. Solutions to increase the size of applicable interface elements are described and cover numerical integration of the element and modifications of the cohesive law....

Social cohesion: The missing link in overcoming violence and ...

International Development Research Centre (IDRC) Digital Library (Canada)

Researchers will test the hypothesis that social cohesion is a critical factor in ... to community members, and ethnographic social network analysis, to help map ... to identify the most effective strategies for addressing these challenges in Latin ...

Drinking water biofilm cohesiveness changes under chlorination or hydrodynamic stress.

Science.gov (United States)

Mathieu, L; Bertrand, I; Abe, Y; Angel, E; Block, J C; Skali-Lami, S; Francius, G

2014-05-15

Attempts at removal of drinking water biofilms rely on various preventive and curative strategies such as nutrient reduction in drinking water, disinfection or water flushing, which have demonstrated limited efficiency. The main reason for these failures is the cohesiveness of the biofilm driven by the physico-chemical properties of its exopolymeric matrix (EPS). Effective cleaning procedures should break up the matrix and/or change the elastic properties of bacterial biofilms. The aim of this study was to evaluate the change in the cohesive strength of two-month-old drinking water biofilms under increasing hydrodynamic shear stress τw (from ∼0.2 to ∼10 Pa) and shock chlorination (applied concentration at T0: 10 mg Cl2/L; 60 min contact time). Biofilm erosion (cell loss per unit surface area) and cohesiveness (changes in the detachment shear stress and cluster volumes measured by atomic force microscopy (AFM)) were studied. When rapidly increasing the hydrodynamic constraint, biofilm removal was found to be dependent on a dual process of erosion and coalescence of the biofilm clusters. Indeed, 56% of the biofilm cells were removed with, concomitantly, a decrease in the number of the 50-300 μm(3) clusters and an increase in the number of the smaller (i.e., 600 μm(3)) ones. Moreover, AFM evidenced the strengthening of the biofilm structure along with the doubling of the number of contact points, NC, per cluster volume unit following the hydrodynamic disturbance. This suggests that the compactness of the biofilm exopolymers increases with hydrodynamic stress. Shock chlorination removed cells (-75%) from the biofilm while reducing the volume of biofilm clusters. Oxidation stress resulted in a decrease in the cohesive strength profile of the remaining drinking water biofilms linked to a reduction in the number of contact points within the biofilm network structure in particular for the largest biofilm cluster volumes (>200 μm(3)). Changes in the cohesive

Isotropic compression of cohesive-frictional particles with rolling resistance

NARCIS (Netherlands)

Luding, Stefan; Benz, Thomas; Nordal, Steinar

2010-01-01

Cohesive-frictional and rough powders are the subject of this study. The behavior under isotropic compression is examined for different material properties involving Coulomb friction, rolling-resistance and contact-adhesion. Under isotropic compression, the density continuously increases according

Performance auditing in EU cohesion policy: what do we know and what should we know?

NARCIS (Netherlands)

Damen, M.; Groenendijk, Nico

2012-01-01

Recently, the European Commission has put forward proposals for the next program period of EU Cohesion Policy (EUCP). Part of these proposals is an increased emphasis on performance management. This paper analyses what we know so far on performance management of EU cohesion funds. It will be argued

Writing Cohesion Using Content Lexical Ties in ESOL.

Science.gov (United States)

Liu, Dilin

2000-01-01

Describes a series of exercises that have proved useful in helping students learning English to enhance their writing skills, particularly cohesion in their writing. Exercises enabled students to learn words in context or in relation to one another as synonyms, antonyms, superordinates, or hyponyms, and a better understanding of these words…

Parenthetical Cohesive Explicitness: A Linguistic Approach for a Modified Translation of the Quranic Text

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Mohammad Amin Hawamdeh

2015-09-01

Full Text Available Motivated by the severe criticism the Hilali and Khan (HK Translation of the Holy Quran has received for its too many parenthetical insertions, this study aimed at linguistically realizing how such added pieces of information could be for necessary cohesive explicitness or worthless redundant interpolation. Methodically, the HK translation of the first 8 verses of Chapter 18 (The Cave, Surah Al Kahf of the Holy Quran was selected to be a subject material. A number of 15 instances of explicitation put in parentheses were encountered; they were found to be based upon 23 cohesive (grammatical/lexical relationships and, hence, to be considered as ones of cohesive explicitness. Eventually, such an analysis could be of use for modifying the available translations of the Holy Quran.

Modeling grain boundaries in polycrystals using cohesive elements: Qualitative and quantitative analysis

Energy Technology Data Exchange (ETDEWEB)

El Shawish, Samir, E-mail: Samir.ElShawish@ijs.si [Jožef Stefan Institute, Jamova cesta 39, SI-1000 Ljubljana (Slovenia); Cizelj, Leon [Jožef Stefan Institute, Jamova cesta 39, SI-1000 Ljubljana (Slovenia); Simonovski, Igor [European Commission, DG-JRC, Institute for Energy and Transport, P.O. Box 2, NL-1755 ZG Petten (Netherlands)

2013-08-15

Highlights: ► We estimate the performance of cohesive elements for modeling grain boundaries. ► We compare the computed stresses in ABAQUS finite element solver. ► Tests are performed in analytical and realistic models of polycrystals. ► Most severe issue is found within the plastic grain response. ► Other identified issues are related to topological constraints in modeling space. -- Abstract: We propose and demonstrate several tests to estimate the performance of the cohesive elements in ABAQUS for modeling grain boundaries in complex spatial structures such as polycrystalline aggregates. The performance of the cohesive elements is checked by comparing the computed stresses with the theoretically predicted values for a homogeneous material under uniaxial tensile loading. Statistical analyses are performed under different loading conditions for two elasto-plastic models of the grains: isotropic elasticity with isotropic hardening plasticity and anisotropic elasticity with crystal plasticity. Tests are conducted on an analytical finite element model generated from Voronoi tessellation as well as on a realistic finite element model of a stainless steel wire. The results of the analyses highlight several issues related to the computation of normal and shear stresses. The most severe issue is found within the plastic grain response where the computed normal stresses on a particularly oriented cohesive elements are significantly underestimated. Other issues are found to be related to topological constraints in the modeling space and result in the increased scatter of the computed stresses.

Role of oxygen free radicals in the induction of sister chromatid exchanges by cigarette smoke

International Nuclear Information System (INIS)

Lee, C.K.; Brown, B.G.; Rice, W.Y. Jr.; Doolittle, D.J.

1989-01-01

Cigarette smoke has been reported to contain free radicals and free radical generators in both the gas and particulate phases. Studies in our laboratory have shown that both cigarette smoke condensate (CSC) and smoke bubbled through phosphate buffered saline solution (smoke-PBS) increased sister chromatid exchanges (SCE) in Chinese hamster ovary cells in a dose-dependent manner. Since oxygen free radicals have been shown to cause SCEs and other chromosomal damage, we investigated the role of these radicals in the induction of SCEs by CSC and smoke-PBS. Addition of the antioxidant enzymes catalase and superoxide dismutase or the oxygen-radical scavenger ascorbic acid failed to reduce the SCE frequency in the presence of either CSC or smoke-PBS. Additional studies indicated that the quantity of hydrogen peroxide produced in CSC or smoke-PBS is too small to account for the observed SCE induction. It appears, therefore, that SCE induction by CSC or smoke-PBS does not involve the participation of oxygen free radicals

Whither Elite Cohesion in Mexico: A Comment

Science.gov (United States)

1988-11-01

the problem of elite cohesion, including the mechanisms-- especially the camarilla system--whereby balance and equilibrium, control and cooptation...Generacicnes: Los Protagonistas de Ia Reforma y la Revoluci(n Mexicana, Secretaria de Educacion Pblica, Consejo Nacional de Fomento Educat ivo, Mexico City...loyalty and discipline toward the system as a whole, and especially its apex, the president, and its key institution, the PRI. All this looks different

APC/C-Cdc20 mediates deprotection of centromeric cohesin at meiosis II in yeast.

Science.gov (United States)

Jonak, Katarzyna; Zagoriy, Ievgeniia; Oz, Tugce; Graf, Peter; Rojas, Julie; Mengoli, Valentina; Zachariae, Wolfgang

2017-06-18

Cells undergoing meiosis produce haploid gametes through one round of DNA replication followed by 2 rounds of chromosome segregation. This requires that cohesin complexes, which establish sister chromatid cohesion during S phase, are removed in a stepwise manner. At meiosis I, the separase protease triggers the segregation of homologous chromosomes by cleaving cohesin's Rec8 subunit on chromosome arms. Cohesin persists at centromeres because the PP2A phosphatase, recruited by the shugoshin protein, dephosphorylates Rec8 and thereby protects it from cleavage. While chromatids disjoin upon cleavage of centromeric Rec8 at meiosis II, it was unclear how and when centromeric Rec8 is liberated from its protector PP2A. One proposal is that bipolar spindle forces separate PP2A from Rec8 as cells enter metaphase II. We show here that sister centromere biorientation is not sufficient to "deprotect" Rec8 at meiosis II in yeast. Instead, our data suggest that the ubiquitin-ligase APC/C Cdc20 removes PP2A from centromeres by targeting for degradation the shugoshin Sgo1 and the kinase Mps1. This implies that Rec8 remains protected until entry into anaphase II when it is phosphorylated concurrently with the activation of separase. Here, we provide further support for this model and speculate on its relevance to mammalian oocytes.

The mitosis-regulating and protein-protein interaction activities of astrin are controlled by aurora-A-induced phosphorylation.

Science.gov (United States)

Chiu, Shao-Chih; Chen, Jo-Mei Maureen; Wei, Tong-You Wade; Cheng, Tai-Shan; Wang, Ya-Hui Candice; Ku, Chia-Feng; Lian, Chiao-Hsuan; Liu, Chun-Chih Jared; Kuo, Yi-Chun; Yu, Chang-Tze Ricky

2014-09-01

Cells display dramatic morphological changes in mitosis, where numerous factors form regulatory networks to orchestrate the complicated process, resulting in extreme fidelity of the segregation of duplicated chromosomes into two daughter cells. Astrin regulates several aspects of mitosis, such as maintaining the cohesion of sister chromatids by inactivating Separase and stabilizing spindle, aligning and segregating chromosomes, and silencing spindle assembly checkpoint by interacting with Src kinase-associated phosphoprotein (SKAP) and cytoplasmic linker-associated protein-1α (CLASP-1α). To understand how Astrin is regulated in mitosis, we report here that Astrin acts as a mitotic phosphoprotein, and Aurora-A phosphorylates Astrin at Ser(115). The phosphorylation-deficient mutant Astrin S115A abnormally activates spindle assembly checkpoint and delays mitosis progression, decreases spindle stability, and induces chromosome misalignment. Mechanistic analyses reveal that Astrin phosphorylation mimicking mutant S115D, instead of S115A, binds and induces ubiquitination and degradation of securin, which sequentially activates Separase, an enzyme required for the separation of sister chromatids. Moreover, S115A fails to bind mitosis regulators, including SKAP and CLASP-1α, which results in the mitotic defects observed in Astrin S115A-transfected cells. In conclusion, Aurora-A phosphorylates Astrin and guides the binding of Astrin to its cellular partners, which ensures proper progression of mitosis. Copyright © 2014 the American Physiological Society.

Visibility and anonymity effects on attraction and group cohesiveness

NARCIS (Netherlands)

Lea, Martin; Spears, Russell; Watt, Susan E.

2007-01-01

This study investigated attraction and group cohesiveness under different visibility and anonymity conditions for social categories that differed in their capacity to be visually cued. Using computer-mediated communication in 36 mixed gender (visually cued category) and nationality (non-visually

Social cohesion, sexuality, homophobia and women's sport in South ...

African Journals Online (AJOL)

... secondly, that the success of national teams and athletes promotes national pride and unity. ... We explore these issues by drawing on media reports of cases in which ... To realise the potential of sport as a tool for building social cohesion, ...

Student leadership and advocacy for social cohesion: A South ...

African Journals Online (AJOL)

at how social cohesion could benefit economic development, hoped thereby ... institutions pledged to reverse 'outsourcing' to 'insourcing' of cleaning services, there is .... It is not so much the scale of these ills as it is the perceived failure of the.

The limits of social capital: Durkheim, suicide, and social cohesion.

Science.gov (United States)

Kushner, Howard I; Sterk, Claire E

2005-07-01

Recent applications of social capital theories to population health often draw on classic sociological theories for validation of the protective features of social cohesion and social integration. Durkheim's work on suicide has been cited as evidence that modern life disrupts social cohesion and results in a greater risk of morbidity and mortality-including self-destructive behaviors and suicide. We argue that a close reading of Durkheim's evidence supports the opposite conclusion and that the incidence of self-destructive behaviors such as suicide is often greatest among those with high levels of social integration. A reexamination of Durkheim's data on female suicide and suicide in the military suggests that we should be skeptical about recent studies connecting improved population health to social capital.

Exploring Advertising Texts in Nigeria within the Framework of Cohesive Influence

Directory of Open Access Journals (Sweden)

Taofeek DALAMU

2018-06-01

Full Text Available The thrust of the study explicates the utilization of grammatical and lexical devices in the texts of advertisements in Nigeria. This exploration aimed at demonstrating the way that advertising professionals wisely move from disjunctive organic elements to clause complexes as a convincing strategy. The advertisements of UBA®, Toyota®, Wema®, etisalat®, Standard Chartered® and Stanbic IBTC® were chosen as analyzable data to explain the behavior of the clause and its complexes in advertising. The conceptual framework is cohesion. Cohesive facilities have been applied as sub-concepts to interpret the constituents of the texts. The study demonstrates that reference, repetition, synonym, fragmented structure are deployed as inciting devices in the discursive strategy. In that sense, the study has the capacity to assist scholars to understand the nature of linguistic elements in clause complexes of advertisements. The analysis also reveals to advertising experts the cohesive resources that can help communicators to achieve intended goals of excitement. The study illuminates the extent at which advertisers take advantage of and associate with events in society to campaign their goods and services to consumers.

The Impact of African American Parents’ Racial Discrimination Experiences and Perceived Neighborhood Cohesion on their Racial Socialization Practices

Science.gov (United States)

English, Devin; Busby, Danielle R.; Lambert, Sharon F.; Harrison, Aubrey; Stock, Michelle L.; Gibbons, Frederick X.

2016-01-01

Parental racial socialization is a parenting tool used to prepare African American adolescents for managing racial stressors. While it is known that parents’ racial discrimination experiences affect the racial socialization messages they provide, little is known about the influence of factors that promote supportive and communal parenting, such as perceived neighborhood cohesion. In cohesive neighborhoods, neighbors may help parents address racial discrimination by monitoring youth and conveying racial socialization messages; additionally, the effect of neighborhood cohesion on parents’ racial socialization may differ for boys and girls because parents socialize adolescents about race differently based on expected encounters with racial discrimination. Therefore, the current study examines how parents’ perception of neighborhood cohesion and adolescents’ gender moderate associations between parents’ racial discrimination experiences and the racial socialization messages they deliver to their adolescents. Participants were a community sample of 608 African American adolescents (54 % girls; mean age = 15.5) and their primary caregivers (86 % biological mothers; mean age = 42.0). Structural equation modeling indicated that parental racial discrimination was associated with more promotion of mistrust messages for boys and girls in communities with low neighborhood cohesion. In addition, parental racial discrimination was associated with more cultural socialization messages about racial pride and history for boys in neighborhoods with low neighborhood cohesion. The findings suggest that parents’ racial socialization messages are influenced by their own racial discrimination experiences and the cohesiveness of the neighborhood; furthermore, the content of parental messages delivered varies based on adolescents’ gender. PMID:27189721

Comprehension challenges in the fourth grade: The roles of text cohesion, text genre, and readers’ prior knowledge

Directory of Open Access Journals (Sweden)

Danielle S. McNamara

2011-07-01

Full Text Available We examined young readers’ comprehension as a function of text genre (narrative, science, text cohesion (high, low, and readers’ abilities (reading decoding skills and world knowledge. The overarching purpose of this study was to contribute to our understanding of the fourth grade slump. Children in grade 4 read four texts, including one high and one low cohesion text from each genre. Comprehension of each text was assessed with 12 multiple-choice questions and free and cued recall. Comprehension was enhanced by increased knowledge: high knowledge readers showed better comprehension than low knowledge readers and narratives were comprehended better than science texts. Interactions between readers’ knowledge levels and text characteristics indicated that the children showed larger effects of knowledge for science than for narrative texts, and those with more knowledge better understood the low cohesion, narrative texts, showing a reverse cohesion effect. Decoding skill benefited comprehension, but effects of text genre and cohesion depended less on decoding skill than prior knowledge. Overall, the study indicates that the fourth grade slump is at least partially attributable to the emergence of complex dependencies between the nature of the text and the reader’s prior knowledge. The results also suggested that simply adding cohesion cues, and not explanatory information, is not likely to be sufficient for young readers as an approach to improving comprehension of challenging texts.

Comprehension challenges in the fourth grade: The roles of text cohesion, text genre, and readers’ prior knowledge

Directory of Open Access Journals (Sweden)

Danielle S. McNAMARA

2011-11-01

Full Text Available We examined young readers’ comprehension as a function of text genre (narrative, science, text cohesion (high, low, and readers’ abilities (reading decoding skills and world knowledge. The overarching purpose of this study was to contribute to our understanding of the fourth grade slump. Children in grade 4 read four texts, including one high and one low cohesion text from each genre. Comprehension of each text was assessed with 12 multiple-choice questions and free and cued recall. Comprehension was enhanced by increased knowledge: high knowledge readers showed bettercomprehension than low knowledge readers and narratives were comprehended better than science texts. Interactions between readers’ knowledge levels and text characteristics indicated that thechildren showed larger effects of knowledge for science than for narrative texts, and those with more knowledge better understood the low cohesion, narrative texts, showing a reverse cohesion effect.Decoding skill benefited comprehension, but effects of text genre and cohesion depended less on decoding skill than prior knowledge. Overall, the study indicates that the fourth grade slump is at leastpartially attributable to the emergence of complex dependencies between the nature of the text and the reader’s prior knowledge. The results also suggested that simply adding cohesion cues, and notexplanatory information, is not likely to be sufficient for young readers as an approach to improving comprehension of challenging texts.

Diversity and social cohesion : the case of Jane-Finch, a highly diverse lower-income Toronto neighbourhood

NARCIS (Netherlands)

Ahmadi, D.

2017-01-01

Diversity has increasingly emerged as the core focus of many studies concerning factors impacting on social cohesion. Various scholars have concluded that diversity is detrimental to cohesion. Most of this research, however, draws generalisations based upon quantitative data and fails to account

THE ROLE OF SOCIAL COHESION AS STRATEGY FOR REDUCING TOURISM SPATIAL CONFLICT

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SARI Suzanna Ratih

2016-12-01

Full Text Available Borobudur as one of the international tourist’s destination in Indonesia which having compromised their sense of identity before, tourists have their own set of images about tourism destinations. In that destination tourists usually create some tourism activities which needed space to facilitate. Many times such condition caused many problems that lead conflict among the local people. People tried to provide some supporting tourist facilities in order to fulfil the needs of tourist’s activities. People will further utilize some spaces of their village to build tourist facilities. Rich people usually dominated this kind of business. This becomes the fact that many of the fears surrounding tourism are closely associated with a wide range of social problems, especially in terms of determining tourism spatial. Each people tried to collect dollar from tourist as much as possible to provide tourism spatial by ignoring “guyub” and “gotong royong” as traditional principle of their live. This may create disharmony among the society and some people will not get the benefit from tourism activities. Therefore, to learn more detail about the role of “guyub and gotong royong” as social cohesion among people in Borobudur, there is a need to do this research in order to give some recommended strategy to solve thr problem regarding social cohesion and tourism spatial. By using descriptive method, researcher would like to present a case study about that matter in one of tourism village in Borobudur. The output of this research is to give an overview how tourism activities give significant influence towards the power of social cohesion in reducing the appeared conflict. The developed strategy will be used to tighten the relationship among the people, through re-empowering the traditional social cohesion so called ”guyub” and “gotong-royong”. By doing so, it is expected that integrity and cohesiveness in a social structure could always be

Cohesion and Coalition Formation in the European Parliament: Roll-Call Votes and Twitter Activities.

Science.gov (United States)

Cherepnalkoski, Darko; Karpf, Andreas; Mozetič, Igor; Grčar, Miha

2016-01-01

We study the cohesion within and the coalitions between political groups in the Eighth European Parliament (2014-2019) by analyzing two entirely different aspects of the behavior of the Members of the European Parliament (MEPs) in the policy-making processes. On one hand, we analyze their co-voting patterns and, on the other, their retweeting behavior. We make use of two diverse datasets in the analysis. The first one is the roll-call vote dataset, where cohesion is regarded as the tendency to co-vote within a group, and a coalition is formed when the members of several groups exhibit a high degree of co-voting agreement on a subject. The second dataset comes from Twitter; it captures the retweeting (i.e., endorsing) behavior of the MEPs and implies cohesion (retweets within the same group) and coalitions (retweets between groups) from a completely different perspective. We employ two different methodologies to analyze the cohesion and coalitions. The first one is based on Krippendorff's Alpha reliability, used to measure the agreement between raters in data-analysis scenarios, and the second one is based on Exponential Random Graph Models, often used in social-network analysis. We give general insights into the cohesion of political groups in the European Parliament, explore whether coalitions are formed in the same way for different policy areas, and examine to what degree the retweeting behavior of MEPs corresponds to their co-voting patterns. A novel and interesting aspect of our work is the relationship between the co-voting and retweeting patterns.

Linking Anger Trait with Somatization in Low-Grade College Students: Moderating Roles of Family Cohesion and Adaptability.

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Liu, Liang; Liu, Cuilian; Zhao, Xudong

2017-02-25

Between 22% and 58% of patients in primary care settings complain of somatic symptoms. Previous research has found that somatization was associated with anger traits and family functions. However, studies that specifically assess the moderating effect of family function in how anger traits become somatic complaints are lacking. This study was designed to examine whether the variances in family cohesion and family adaptability moderated the strength of the relationship between anger traits and somatization. A cross-section design was conducted and 2008 college students were recruited from a comprehensive university in Shanghai. All participants finished questionnaires including Symptom Check List- 90 (SCL-90), State-Trait Anger Expression Inventory 2 (STAXI-2, Chinese version) and Family Adaptability and Cohesion Scale, second edition (FACES II, Chinese Version) to assess their degree of current somatization, anger trait and family function. Hierarchical linear regression analysis (Enter) was conducted respectively for men and women to examine the moderation effect of family cohesion and family adaptability in the association between anger and somatization. Somatic symptoms were significantly linked in the expected directions with depression and anger trait for both genders. Family cohesion and family adaptability were negatively associated with somatic symptoms. For female college students family cohesion was found to moderate the link between anger trait and somatization, but for male college students the moderation effect of family cohesion was marginally significant. The moderating role of family adaptability was significant for neither male nor female after current depressive symptoms were accounted for. Proneness to anger is an independent predictor of somatization. For women, a high level of family cohesion was a protective factor which could reduce the influence of anger trait on somatic symptoms. Without comorbidity of current depression, family

The impact of neighborhood violence and social cohesion on smoking behaviors among a cohort of smokers in Mexico

Science.gov (United States)

Fleischer, Nancy L.; Lozano, Paula; Santillán, Edna Arillo; Shigematsu, Luz Myriam Reynales; Thrasher, James F.

2016-01-01

Background Recent increases in violent crime may impact a variety of health outcomes in Mexico. We examined relationships between neighborhood-level violence and smoking behaviors in a cohort of Mexican smokers from 2011–2012, and whether neighborhood-level social cohesion modified these relationships. Methods Data were analyzed from adult smokers and recent ex-smokers who participated in Waves 5–6 of the International Tobacco Control Mexico Survey. Self-reported neighborhood violence and social cohesion were asked of Wave 6 survey participants (n=2129 current and former smokers, n=150 neighborhoods). Neighborhood-level averages for violence and social cohesion (range 4–14 and 10–25, respectively) were assigned to individuals. We used generalized estimating equations to determine associations between neighborhood indicators and individual-level smoking intensity, quit behaviors, and relapse. Results Higher neighborhood violence was associated with higher smoking intensity (Risk Ratio (RR)=1.17, 95% Confidence Interval (CI) 1.02–1.33), and fewer quit attempts (RR=0.72, 95% CI 0.61–0.85). Neighborhood violence was not associated with successful quitting or relapse. Higher neighborhood social cohesion was associated with more quit attempts and more successful quitting. Neighborhood social cohesion modified the association between neighborhood violence and smoking intensity: in neighborhoods with higher social cohesion, as violence increased, smoking intensity decreased and in neighborhoods with lower social cohesion, as violence increased, so did smoking intensity. Conclusion In the context of recent increased violence in Mexico, smokers living in neighborhoods with more violence may smoke more cigarettes per day and make fewer quit attempts than their counterparts in less violent neighborhoods. Neighborhood social cohesion may buffer the impact of violence on smoking intensity. PMID:26043898

Sensitivity and spin-up times of cohesive sediment transport models used to simulate bathymetric change: Chapter 31

Science.gov (United States)

Schoellhamer, D.H.; Ganju, N.K.; Mineart, P.R.; Lionberger, M.A.; Kusuda, T.; Yamanishi, H.; Spearman, J.; Gailani, J. Z.

2008-01-01

Bathymetric change in tidal environments is modulated by watershed sediment yield, hydrodynamic processes, benthic composition, and anthropogenic activities. These multiple forcings combine to complicate simple prediction of bathymetric change; therefore, numerical models are necessary to simulate sediment transport. Errors arise from these simulations, due to inaccurate initial conditions and model parameters. We investigated the response of bathymetric change to initial conditions and model parameters with a simplified zero-dimensional cohesive sediment transport model, a two-dimensional hydrodynamic/sediment transport model, and a tidally averaged box model. The zero-dimensional model consists of a well-mixed control volume subjected to a semidiurnal tide, with a cohesive sediment bed. Typical cohesive sediment parameters were utilized for both the bed and suspended sediment. The model was run until equilibrium in terms of bathymetric change was reached, where equilibrium is defined as less than the rate of sea level rise in San Francisco Bay (2.17 mm/year). Using this state as the initial condition, model parameters were perturbed 10% to favor deposition, and the model was resumed. Perturbed parameters included, but were not limited to, maximum tidal current, erosion rate constant, and critical shear stress for erosion. Bathymetric change was most sensitive to maximum tidal current, with a 10% perturbation resulting in an additional 1.4 m of deposition over 10 years. Re-establishing equilibrium in this model required 14 years. The next most sensitive parameter was the critical shear stress for erosion; when increased 10%, an additional 0.56 m of sediment was deposited and 13 years were required to re-establish equilibrium. The two-dimensional hydrodynamic/sediment transport model was calibrated to suspended-sediment concentration, and despite robust solution of hydrodynamic conditions it was unable to accurately hindcast bathymetric change. The tidally averaged

Improving decision speed, accuracy and group cohesion through early information gathering in house-hunting ants.

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Stroeymeyt, Nathalie; Giurfa, Martin; Franks, Nigel R

2010-09-29

Successful collective decision-making depends on groups of animals being able to make accurate choices while maintaining group cohesion. However, increasing accuracy and/or cohesion usually decreases decision speed and vice-versa. Such trade-offs are widespread in animal decision-making and result in various decision-making strategies that emphasize either speed or accuracy, depending on the context. Speed-accuracy trade-offs have been the object of many theoretical investigations, but these studies did not consider the possible effects of previous experience and/or knowledge of individuals on such trade-offs. In this study, we investigated how previous knowledge of their environment may affect emigration speed, nest choice and colony cohesion in emigrations of the house-hunting ant Temnothorax albipennis, a collective decision-making process subject to a classical speed-accuracy trade-off. Colonies allowed to explore a high quality nest site for one week before they were forced to emigrate found that nest and accepted it faster than emigrating naïve colonies. This resulted in increased speed in single choice emigrations and higher colony cohesion in binary choice emigrations. Additionally, colonies allowed to explore both high and low quality nest sites for one week prior to emigration remained more cohesive, made more accurate decisions and emigrated faster than emigrating naïve colonies. These results show that colonies gather and store information about available nest sites while their nest is still intact, and later retrieve and use this information when they need to emigrate. This improves colony performance. Early gathering of information for later use is therefore an effective strategy allowing T. albipennis colonies to improve simultaneously all aspects of the decision-making process--i.e. speed, accuracy and cohesion--and partly circumvent the speed-accuracy trade-off classically observed during emigrations. These findings should be taken into account

Mek1/Mre4 is a master regulator of meiotic recombination in budding yeast

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Nancy M. Hollingsworth

2016-02-01

Full Text Available Sexually reproducing organisms create gametes with half the somatic cell chromosome number so that fusion of gametes at fertilization does not change the ploidy of the cell. This reduction in chromosome number occurs by the specialized cell division of meiosis in which two rounds of chromosome segregation follow a single round of chromosome duplication. Meiotic crossovers formed between the non-sister chromatids of homologous chromosomes, combined with sister chromatid cohesion, physically connect homologs, thereby allowing proper segregation at the first meiotic division. Meiotic recombination is initiated by programmed double strand breaks (DSBs whose repair is highly regulated such that (1 there is a bias for recombination with homologs rather than sister chromatids, (2 crossovers are distributed throughout the genome by a process called interference, (3 crossover homeostasis regulates the balance between crossover and non-crossover repair to maintain a critical number of crossovers and (4 each pair of homologs receives at least one crossover. It was previously known that the imposition of interhomolog bias in budding yeast requires meiosis-specific modifications to the DNA damage response and the local activation of the meiosis-specific Mek1/Mre4 (hereafter Mek1 kinase at DSBs. However, because inactivation of Mek1 results in intersister, rather than interhomolog DSB repair, whether Mek1 had a role in interhomolog pathway choice was unknown. A recent study by Chen et al. (2015 reveals that Mek1 indirectly regulates the crossover/non-crossover decision between homologs as well as genetic interference. It does this by enabling phosphorylation of Zip1, the meiosis-specific transverse filament protein of the synaptonemal complex (SC, by the conserved cell cycle kinase, Cdc7-Dbf4 (DDK. These results suggest that Mek1 is a “master regulator” of meiotic recombination in budding yeast.

Self-Esteem among Vietnamese American Adolescents: The Role of Self-Construal, Family Cohesion, and Social Support

Science.gov (United States)

Lam, Brian Trung

2005-01-01

This prospective study examined whether interdependent self-construal (collectivism), independent self-construal (individualism), family cohesion, and social support would predict levels of self-esteem among Vietnamese American adolescents. Standardized self-report measures of family cohesion, social support, and self-esteem, as well as a measure…

Cohesive fracture model for functionally graded fiber reinforced concrete

International Nuclear Information System (INIS)

Park, Kyoungsoo; Paulino, Glaucio H.; Roesler, Jeffery

2010-01-01

A simple, effective, and practical constitutive model for cohesive fracture of fiber reinforced concrete is proposed by differentiating the aggregate bridging zone and the fiber bridging zone. The aggregate bridging zone is related to the total fracture energy of plain concrete, while the fiber bridging zone is associated with the difference between the total fracture energy of fiber reinforced concrete and the total fracture energy of plain concrete. The cohesive fracture model is defined by experimental fracture parameters, which are obtained through three-point bending and split tensile tests. As expected, the model describes fracture behavior of plain concrete beams. In addition, it predicts the fracture behavior of either fiber reinforced concrete beams or a combination of plain and fiber reinforced concrete functionally layered in a single beam specimen. The validated model is also applied to investigate continuously, functionally graded fiber reinforced concrete composites.

Group cohesion and social support in exercise classes: results from a danish intervention study

DEFF Research Database (Denmark)

Christensen, Ulla; Schmidt, Lone; Budtz-Jørgensen, Esben

2006-01-01

This study examines the formation of group cohesion and social support in exercise classes among former sedentary adults, participating in a Danish community-based intervention. Furthermore, the aim is to analyze the impact of this process on exercise activity among the participants. A multimethod...... approach was used, analyzing both survey data and 18 personal interviews collected among 87 participants who completed the intervention project. Analysis was performed according to the grounded theory method. The formation of group cohesion was conditioned by the social composition of the group......, the teaching ability by the instructors, and the activity by itself. The cohesive group was characterized by an attitude of mutual support toward exercise activities. This mutual support facilitated development of self-efficacy beliefs among the participants improving their mastery expectation regarding...

Stress of home life and gender role socializations, family cohesion, and symptoms of anxiety and depression.

Science.gov (United States)

Anyan, Frederick; Hjemdal, Odin

2017-04-05

This cross-sectional study investigated the relation of sociocultural prescriptions of gender role socializations to differences in stress at home and to anxiety and depressive symptoms for adolescent girls and boys, with family cohesion as a mediator. A total of 244 boys and 285 girls aged 13-17 years recruited from Accra, Ghana completed the Short Mood Feeling Questionnaire, Spielberger State Anxiety Inventory, Stress of Home Life and Family Cohesion self-report scales in April 2015. In each sample, two mediation analyses were conducted using Structural Equation Modelling. Exposure to stress at home that was perceived to result from sociocultural prescriptions of gender role norms largely accounted for anxiety and depressive symptoms among girls, whereas this relation was non-significant among boys. Significant indirect relations through low family cohesion to anxiety symptoms were observed for girls and boys but not to depressive symptoms for boys. These findings suggest that differences in gender role socializations at home may account for individual differences in associations between exposure to stress at home and anxiety and depressive symptoms as well as explain the differential indirect relations through low family cohesion. Improving family cohesion while reducing stress at home may contribute to reducing stress and thus anxiety and depressive symptoms.

Cohesion, team mental models, and collective efficacy: towards an integrated framework of team dynamics in sport.

Science.gov (United States)

Filho, Edson; Tenenbaum, Gershon; Yang, Yanyun

2015-01-01

A nomological network on team dynamics in sports consisting of a multiframework perspective is introduced and tested. The aim was to explore the interrelationship among cohesion, team mental models (TMMs), collective efficacy (CE) and perceived performance potential (PPP). Three hundred and forty college-aged soccer players representing 17 different teams (8 female and 9 male) participated in the study. They responded to surveys on team cohesion, TMMs, CE and PPP. Results are congruent with the theoretical conceptualisation of a parsimonious view of team dynamics in sports. Specifically, cohesion was found to be an exogenous variable predicting both TMMs and CE beliefs. TMMs and CE were correlated and predicted PPP, which in turn accounted for 59% of the variance of objective performance scores as measured by teams' season record. From a theoretical standpoint, findings resulted in a parsimonious view of team dynamics, which may represent an initial step towards clarifying the epistemological roots and nomological network of various team-level properties. From an applied standpoint, results suggest that team expertise starts with the establishment of team cohesion. Following the establishment of cohesiveness, teammates are able to advance team-related schemas and a collective sense of confidence. Limitations and key directions for future research are outlined.

A social network analysis of social cohesion in a constructed pride: implications for ex situ reintroduction of the African lion (Panthera leo.

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Jackie Abell

Full Text Available Animal conservation practices include the grouping of captive related and unrelated individuals to form a social structure which is characteristic of that species in the wild. In response to the rapid decline of wild African lion (Panthera leo populations, an array of conservational strategies have been adopted. Ex situ reintroduction of the African lion requires the construction of socially cohesive pride structures prior to wild release. This pilot study adopted a social network theory approach to quantitatively assess a captive pride's social structure and the relationships between individuals within them. Group composition (who is present in a group and social interaction data (social licking, greeting, play was observed and recorded to assess social cohesion within a released semi-wild pride. UCINET and SOCPROG software was utilised to represent and analyse these social networks. Results indicate that the pride is socially cohesive, does not exhibit random associations, and the role of socially influential keystone individuals is important for maintaining social bondedness within a lion pride. These results are potentially informative for the structure of lion prides, in captivity and in the wild, and could have implications for captive and wild-founder reintroductions.

A social network analysis of social cohesion in a constructed pride: implications for ex situ reintroduction of the African lion (Panthera leo).

Science.gov (United States)

Abell, Jackie; Kirzinger, Morgan W B; Gordon, Yvonne; Kirk, Jacqui; Kokeŝ, Rae; Lynas, Kirsty; Mandinyenya, Bob; Youldon, David

2013-01-01

Animal conservation practices include the grouping of captive related and unrelated individuals to form a social structure which is characteristic of that species in the wild. In response to the rapid decline of wild African lion (Panthera leo) populations, an array of conservational strategies have been adopted. Ex situ reintroduction of the African lion requires the construction of socially cohesive pride structures prior to wild release. This pilot study adopted a social network theory approach to quantitatively assess a captive pride's social structure and the relationships between individuals within them. Group composition (who is present in a group) and social interaction data (social licking, greeting, play) was observed and recorded to assess social cohesion within a released semi-wild pride. UCINET and SOCPROG software was utilised to represent and analyse these social networks. Results indicate that the pride is socially cohesive, does not exhibit random associations, and the role of socially influential keystone individuals is important for maintaining social bondedness within a lion pride. These results are potentially informative for the structure of lion prides, in captivity and in the wild, and could have implications for captive and wild-founder reintroductions.

The Importance of Structural and Cohesion Funds on Regional Development in Romania

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Manuela Panaitescu

2013-05-01

Full Text Available Objectives: the financing of regional policy and, in general terms, of the economic and social cohesion from structural and cohesion funds is important due to its results, with regard to costs and net benefits on the development of Romania; Prior Work: this work continues prior research carried out for the “European Programs and Projects Management” MA thesis; Approach: the primary methods used were the analysis of the legal framework and other official European documents and the observation of their influence on Romania; Results: While during the pre-accession period the financial instruments created by the EU for Romania had been made after the model of structural and cohesion funds, precisely in order to get the national authorities ready for the reality implied by its membership, the EU common position on regional policy and coordination of structural instruments and documents further stated that the Romanian authorities do not yet have the adequate capacity to manage the structural instruments, which obviously has implications in terms of costs.

Balancing act: the influence of adaptability and cohesion on satisfaction and communication in families facing TBI in Mexico.

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Lehan, Tara J; Stevens, Lillian Flores; Arango-Lasprilla, Juan Carlos; Díaz Sosa, Dulce María; Espinosa Jove, Irma Guadalupe

2012-01-01

Much of what is known about family functioning in the face of traumatic brain injury (TBI) is based on research conducted in the United States. The purpose of this study was to (1) describe the levels of family adaptability, cohesion, communication, and satisfaction as reported by Mexican TBI survivors and their family caregivers, (2) test the hypothesis of the Circumplex Model that balanced families would exhibit better communication and greater satisfaction, and (3) explore how TBI survivors' and their family caregivers' perceptions of family adaptability and cohesion influenced their own and the other's perceptions of family communication and satisfaction. In the majority of dyads, both the TBI survivor and the family caregiver endorsed balanced family adaptability and cohesion. Both TBI survivors and their family caregivers reported a relatively high level of family communication and satisfaction. TBI survivors and family caregivers who reported greater levels of family adaptability and cohesion also endorsed better family communication and greater family satisfaction. In addition, individuals with TBI whose family caregiver endorsed balanced family adaptability and cohesion reported better family communication. Further, family caregivers of TBI survivors who reported balanced family adaptability and cohesion reported better family communication. Implications for research and practice are discussed.

A cohesive finite element formulation for modelling fracture and ...

Indian Academy of Sciences (India)

cohesive elements experience material softening and lose their stress carrying capacity. A few simple ..... In the present work, a Lagrangian finite element procedure is employed. In this formu clation ...... o, is related to 'c o by,. 't o='c o ¼ 1 ہ. 1.

The Impact of African American Parents' Racial Discrimination Experiences and Perceived Neighborhood Cohesion on their Racial Socialization Practices.

Science.gov (United States)

Saleem, Farzana T; English, Devin; Busby, Danielle R; Lambert, Sharon F; Harrison, Aubrey; Stock, Michelle L; Gibbons, Frederick X

2016-07-01

Parental racial socialization is a parenting tool used to prepare African American adolescents for managing racial stressors. While it is known that parents' racial discrimination experiences affect the racial socialization messages they provide, little is known about the influence of factors that promote supportive and communal parenting, such as perceived neighborhood cohesion. In cohesive neighborhoods, neighbors may help parents address racial discrimination by monitoring youth and conveying racial socialization messages; additionally, the effect of neighborhood cohesion on parents' racial socialization may differ for boys and girls because parents socialize adolescents about race differently based on expected encounters with racial discrimination. Therefore, the current study examines how parents' perception of neighborhood cohesion and adolescents' gender moderate associations between parents' racial discrimination experiences and the racial socialization messages they deliver to their adolescents. Participants were a community sample of 608 African American adolescents (54 % girls; mean age = 15.5) and their primary caregivers (86 % biological mothers; mean age = 42.0). Structural equation modeling indicated that parental racial discrimination was associated with more promotion of mistrust messages for boys and girls in communities with low neighborhood cohesion. In addition, parental racial discrimination was associated with more cultural socialization messages about racial pride and history for boys in neighborhoods with low neighborhood cohesion. The findings suggest that parents' racial socialization messages are influenced by their own racial discrimination experiences and the cohesiveness of the neighborhood; furthermore, the content of parental messages delivered varies based on adolescents' gender.

NON-COHESIVE SOIL DIRECT SHEAR STRENGTH AFFECTED WITH HYDROSTATIC PRESSURE

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Tadas Tamošiūnas

2017-12-01

Full Text Available This paper presents first results of non­cohesive soil direct shear tests with hydrostatic pressure. To reach this aim, it was chosen the Baltic Sea Klaipėda sand, due to granulometry composition and particles shape. According to this, investigated Baltic Sea sand can be called Lithuanian standard sand for scientific testing. Analysis of results revealed, that when it is increased hydrostatic pressure, the shearing strength is also increasing. Comparing air­ dry sand results with fully saturated sand and affected with 100 kPa of hydrostatic pressure, the angle of internal friction increased for 21,24%. Meanwhile, the cohesion was not changing so dramatically according to hydrostatic pressure change. Obtained results allows to proceed this research work more detailed with different loading types, testing procedures and hydrostatic pressures.

The Types of Cohesion Used in the ‘Issues of the Day’ Strip in the Jakarta Post

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Wulan Agustina

2015-06-01

Full Text Available This study is aimed at describing discourse studies especially at cohesion from reader’s opinion strip. This is literary research, so the writer uses descriptive qualitative approach. In this research, documentation and note taking technique are used to collect the data. There are two objectives of the research: 1 to carry out the types of grammatical cohesion used in the “Issues of the Day” strip in The Jakarta Post on March 2012 edition and 2 to find out the types of lexical cohesion used in the “Issues of The Day” strip in The Jakarta Post on March 2012 edition. After investigating the English sentences used in the “Issues of the Day” strip in The Jakarta Post on March 2012 edition, the writer found several findings as follows: 1 based on the analysis of grammatical cohesion, the writer found there are references, substitutions, ellipsis, and conjunctions; 2 based on the analysis of lexical cohesion, the writer found repetitions, synonyms, hyponyms, meronyms, antonyms, and collocations. The writer expects that it is able to contribute the science of linguistic and able to be guidance for all readers.

Implementation Of Management Strategic To Team Learning Cohesion In Study Program Of Nursing

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Dr. Susila Sumartiningsih

2015-06-01

Full Text Available ABSTRACT The purpose of this research is to analyze the empiric of management strategic Driving Factor DF and Pull Factor PF to team learning cohesion among nursing program in Banten Provinsion. The study was designed in the quantitative descriptive correlational study and the method was a cross sectional. The total sampling n192 were manager n3 lecturers n45 and students n144 at nursing program study among Banten provice in Indonesia. The data were analyzed by using the Chi-Square.Theresults were showngood category 83.33 in DF and PF of Management Stratgict Implementataion and high category 59.72 in Team Learning Cohesion. There was not a statistically significant relationship p 0.543 p amp8805 0.05 between the DF and PF of team learning cohesion in implementation of Management Stratgic. In view of this it can be concluded that the nursing lecturer should be able to be a good motivator in order to encourage the student academic achievement.

Arabidopsis thaliana WAPL is essential for the prophase removal of cohesin during meiosis.

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Kuntal De

2014-07-01

Full Text Available Sister chromatid cohesion, which is mediated by the cohesin complex, is essential for the proper segregation of chromosomes in mitosis and meiosis. The establishment of stable sister chromatid cohesion occurs during DNA replication and involves acetylation of the complex by the acetyltransferase CTF7. In higher eukaryotes, the majority of cohesin complexes are removed from chromosomes during prophase. Studies in fly and human have shown that this process involves the WAPL mediated opening of the cohesin ring at the junction between the SMC3 ATPase domain and the N-terminal domain of cohesin's α-kleisin subunit. We report here the isolation and detailed characterization of WAPL in Arabidopsis thaliana. We show that Arabidopsis contains two WAPL genes, which share overlapping functions. Plants in which both WAPL genes contain T-DNA insertions show relatively normal growth and development but exhibit a significant reduction in male and female fertility. The removal of cohesin from chromosomes during meiotic prophase is blocked in Atwapl mutants resulting in chromosome bridges, broken chromosomes and uneven chromosome segregation. In contrast, while subtle mitotic alterations are observed in some somatic cells, cohesin complexes appear to be removed normally. Finally, we show that mutations in AtWAPL suppress the lethality associated with inactivation of AtCTF7. Taken together our results demonstrate that WAPL plays a critical role in meiosis and raises the possibility that mechanisms involved in the prophase removal of cohesin may vary between mitosis and meiosis in plants.

EXAMINATION OF HANDBALL PLAYERS’ TEAM COHESION

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İlyas Görgüt

2017-04-01

Full Text Available The aim of this study was to determine team cohesion of handballplayers who were actively engaged in sport in various categories. The study group consisted of a total of 607 handball players, 317 female and 290 male, selected by random method and from 11 provinces of Turkey according to the some factors. When we examine the age distributions of the participants, 121 athletes appear to be 13 years and under, 309 athletes 14-18 years, 94 athletes 19-23 years, 54 athletes 24-28 years and 29 athletes 29 years and over. In addition, 186 of them expressed their education situation as middle school, 253 of them expressed their education situation as high school and 168 of them expressed their education situation as university. Personal information form and team cohesion scale, developed by Widmeyer et al. (1985 and adapted to Turkish by Moralı (1994, were used as a data collecting tools. The Kolmogorov Smirnov test was used to measure whether the obtained data showed normal distribution or not and nonparametric tests were used to determine the subscale scores because they didn’t show normal disturbance. For binary comparisons Mann Whitney U test, for multiple comparisons Kruskal Wallis variance and for the difference between significant groups Bonferroni Mann Whitney U test were used. As a result of the research, there were significant differences in scale subscale scores in terms of gender, age, educational status, sports experience, income and province variables of handball players.

A community based intervention program to enhance neighborhood cohesion: The Learning Families Project in Hong Kong.

Science.gov (United States)

Shen, Chen; Wan, Alice; Kwok, Lit Tung; Pang, Sally; Wang, Xin; Stewart, Sunita M; Lam, Tai Hing; Chan, Sophia S

2017-01-01

Neighborhood cohesion, which refers to the extent of the connectedness and solidarity among residents in a community or neighborhood, is an important determinant of human health. To enhance neighborhood cohesion, the "Learning Families Project" was developed with a series of intervention programs in Kwun Tong in Hong Kong, a district with low neighborhood cohesion. This project, based on the social ecological model, provided a platform for neighbors to learn, communicate and interact with each other. This quasi-experimental study included two nearby government subsidized low rent housing estates separated by busy main roads. One served as the intervention (Tsui Ping (South) Estate) and one as the control (Shun Tin Estate) estate. The intervention included promotion, resident training and learning programs, embodied by a series of community activities such as talks, day camp, thematic activities and horticulture class. Baseline (before the programs) and follow-up (one year after the programs) surveys were conducted both in the intervention and control estate to assess the impact of the programs on neighborhood cohesion. The number of residents who completed both the baseline and follow-up surveys was 502 in the intervention estate and 476 in the control estate. Neighborhood cohesion significantly improved in the intervention group after the programs (Cohen effect size d: 0.15). Compared with the control group, the improvements in closeness of the neighborhood and trust in neighbors were significantly greater in the intervention group (Cohen effect size d: 0.13 and 0.14, respectively). This brief intervention program using a quasi-experimental study design increased neighborhood cohesion in a low rent housing estate. ClinicalTrials.gov NCT02851667.

Cohesive Zone Model Based Numerical Analysis of Steel-Concrete Composite Structure Push-Out Tests

Directory of Open Access Journals (Sweden)

J. P. Lin

2014-01-01

Full Text Available Push-out tests were widely used to determine the shear bearing capacity and shear stiffness of shear connectors in steel-concrete composite structures. The finite element method was one efficient alternative to push-out testing. This paper focused on a simulation analysis of the interface between concrete slabs and steel girder flanges as well as the interface of the shear connectors and the surrounding concrete. A cohesive zone model was used to simulate the tangential sliding and normal separation of the interfaces. Then, a zero-thickness cohesive element was implemented via the user-defined element subroutine UEL in the software ABAQUS, and a multiple broken line mode was used to define the constitutive relations of the cohesive zone. A three-dimensional numerical analysis model was established for push-out testing to analyze the load-displacement curves of the push-out test process, interface relative displacement, and interface stress distribution. This method was found to accurately calculate the shear capacity and shear stiffness of shear connectors. The numerical results showed that the multiple broken lines mode cohesive zone model could describe the nonlinear mechanical behavior of the interface between steel and concrete and that a discontinuous deformation numerical simulation could be implemented.

Examining the Relationship between Emotional Intelligence and Group Cohesion

Science.gov (United States)

Moore, Amanda; Mamiseishvili, Ketevan

2012-01-01

Collaborative learning experiences increase student learning, but what happens when students fail to collaborate? The authors investigated the relationship between emotional intelligence and group cohesion by studying 44 undergraduate teams who were completing semester-long projects in their business classes at a small private university in the…

Interfacial stresses in strengthened beam with shear cohesive zone ...

Indian Academy of Sciences (India)

The results of parametric study are compared with those of Smith and Teng. They confirm the accuracy of the proposed approach in predicting both interfacial shear and normal stresses. Keywords. Strengthened beam; interfacial stresses; cohesive zone; shear deformation. 1. Introduction. The FRP plates can be either ...

Leadership, Cohesion, and Team Norms Regarding Cheating and Aggression.

Science.gov (United States)

Shields, David Lyle Light; And Others

1995-01-01

Study explored leadership, cohesion, and demographic variables in relation to team norms about cheating and aggression. Surveys of high school and college ball players indicated that older age, higher year in school, and more years playing ball correlated positively with expectations of peer cheating and aggression. (SM)

Family Cohesion and Level of Communication Between Parents and ...

African Journals Online (AJOL)

This study investigated the level of communication between parents and their adolescent children and how such communication affects family cohesion. A sample of 200 subjects made up of adolescents and parents were selected through cluster, stratified and random sampling techniques from ten Local Government Areas ...

Numerical simulation of particle settling and cohesion in liquid

Energy Technology Data Exchange (ETDEWEB)

Johno, Y; Nakashima, K; Shigematsu, T; Ono, B [SASEBO National College of Technology, 1-1 Okishin, Sasebo, Nagasaki, 857-1193 (Japan); Satomi, M, E-mail: yjohno@post.cc.sasebo.ac.j [Sony Semiconductor Kyushu Corporation, Kikuchigun, Kumamoto (Japan)

2009-02-01

In this study, the motions of particles and particle clusters in liquid were numerically simulated. The particles of two sizes (Dp=40mum and 20mum) settle while repeating cohesion and dispersion, and finally the sediment of particles are formed at the bottom of a hexahedron container which is filled up with pure water. The flow field was solved with the Navier-Stokes equations and the particle motions were solved with the Lagrangian-type motion equations, where the interaction between fluid and particles due to drag forces were taken into account. The collision among particles was calculated using Distinct Element Method (DEM), and the effects of cohesive forces by van der Waals force acting on particle contact points were taken into account. Numerical simulations were performed under conditions in still flow and in shear flow. It was found that the simulation results enable us to know the state of the particle settling and the particle condensation.

Can consumption of raw vegetables decrease the count of sister chromatid exchange? Results from a cross-sectional study in Krakow, Poland.

Science.gov (United States)

Galas, Aleksander; Cebulska-Wasilewska, Antonina

2015-03-01

Sister chromatid exchange (SCE) is a widely used sensitive cytogenetic biomarker of exposure to genotoxic and cancerogenic agents. Results of human monitoring studies and cytogenetic damage have revealed that biological effects of genotoxic exposures are influenced by confounding factors related to life-style. Vegetable and fruit consumption may play a role, but available results are not consistent. The purpose of the study was to investigate the effect of consumption of raw and cooked vegetables and fruits on SCE frequency. A total of 62 participants included colorectal cancer (CRC) patients, hospital-based controls and healthy laboratory workers. SCE frequency was assessed in blood lymphocytes. Frequency of vegetable and fruit consumption was gathered by structured semi-quantitative food frequency questionnaire. SCE frequency was lowest among hospital-based controls (4.4 ± 1.1), a bit higher in CRC patients (4.5 ± 1.0) and highest among laboratory workers (7.4 ± 1.2) (p consumption, but not so for intake of cooked vegetables and fruits. The results of the study have shown the beneficial effect of consumption of raw vegetables on disrupted replication of DNA measured by SCE frequency, implying protection against genotoxic agents. Further effort is required to verify the role of cooked vegetables and fruits.

Experiences of street harassment and associations with perceptions of social cohesion among women in Mexico City

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Paola A Campos

2017-01-01

Full Text Available Objective. To document the frequency and forms of street harassment and examine the association between street harassment experiences and perceptions of social cohesion. Materials and methods. Baseline survey data collected among women seeking care in public health clinics in Mexico City were used for analysis. Results. Nearly two-thirds (62.8% of women reported experiencing some form of street harassment in the prior month; women with street harassment experiences reported significantly lower perceived social cohesion (b=-0.46; 95%CI:0.69,-0.22. Conclusions. Findings indicate reducing street harassment may have important implications for improving women’s perceived social cohesion and their safety in Mexico City.

Social cohesion and interpersonal conflicts in projects

OpenAIRE

Ojiako, Udechukwu; Manville, Graham; Zouk, Nadine; Chipulu, Maxwell

2016-01-01

One particular area of project management literature that has continued to gain momentum in literature is its social dimension; with a number of scholars emphasising the fact that there is a considerable social dimension to every project activity. Within this context, the authors examine parameters that drive social facets of projects with a particular focus on social cohesion, interpersonal conflicts and national culture. Data from 167 project managers working in Kuwait were collected utilis...

Interparental Conflict and Family Cohesion: Predictors of Loneliness, Social Anxiety, and Social Avoidance in Late Adolescence.

Science.gov (United States)

Johnson, H. Durell; LaVoie, Joseph C.; Mahoney, Molly

2001-01-01

Examined relationship of family cohesion and interparental conflict with loneliness in 124 late adolescents. Found that feelings of loneliness were related to perceived levels of interparental conflict for males and females, and to decreased family cohesion for females. Feelings of social anxiety and social avoidance were related to feelings of…

Social cohesiveness and absenteeism - The relationship between characteristics of employees and short-term absenteeism within an organization

NARCIS (Netherlands)

Sanders, K; Nauta, A

2004-01-01

This study tries to explain the relationship between characteristics of the employees (e.g., gender and working hours) and short-term absenteeism by examining the social cohesiveness of a team. Hypotheses are formulated concerning gender and working hours of employees, social cohesiveness, and

Social cohesiveness and absenteeism : the relationship between characteristics of employees and short-term absenteeism within an organization

NARCIS (Netherlands)

Sanders, K.; Nauta, A.

2004-01-01

This article tries to explain the relationship between characteristics of the employees as gender and working hours, and short-term absenteeism by examining the social cohesiveness of a team. Hypotheses are formulated concerning gender and working hours of employees, social cohesiveness, and

Teacher Governance Factors and Social Cohesion: Insights from Pakistan

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Halai, Anjum; Durrani, Naureen

2016-01-01

This paper explores teacher governance factors, particularly recruitment and deployment of teachers, in relation to inequalities and social cohesion. Pakistan introduced major reforms in education in the post 9/11 context of escalating conflict. These include a merit and needs-based policy on teacher recruitment to eliminate corruption in…

Explaining Couple Cohesion in Different Types of Gay Families

Science.gov (United States)

van Eeden-Moorefield, Brad; Pasley, Kay; Crosbie-Burnett, Margaret; King, Erin

2012-01-01

This Internet-based study used data from a convenience sample of 176 gay men in current partnerships to examine differences in outness, cohesion, and relationship quality between three types of gay male couples: first cohabiting partnerships, repartnerships, and gay stepfamilies. Also, we tested whether relationship quality mediated the link…

Botswana team sport players' perception of cohesion and imagery ...

African Journals Online (AJOL)

Perception of cohesion and imagery use among 45 elite team sport players in Botswana were assessed with the Group Environment Questionnaire (Carron et al., 1985) and the Sport Imagery Questionnaire (Hall et al., 1998) to determine whether a relationship exists between the variables, and whether imagery use will ...

STAG2 and Rad21 mammalian mitotic cohesins are implicated in meiosis

OpenAIRE

Prieto, Ignacio; Pezzi, Nieves; Buesa, José M.; Kremer, Leonor; Barthelemy, Isabel; Carreiro, Candelas; Roncal, Fernando; Martínez, Alicia; Gómez, Lucio; Fernández, Raúl; Martínez-A, Carlos; Barbero, José L.

2002-01-01

STAG/SA proteins are specific cohesin complex subunits that maintain sister chromatid cohesion in mitosis and meiosis. Two members of this family, STAG1/SA1 and STAG2/SA2,‡ are classified as mitotic cohesins, as they are found in human somatic cells and in Xenopus laevis as components of the cohesinSA1 and cohesinSA2 complexes, in which the shared subunits are Rad21/SCC1, SMC1 and SMC3 proteins. A recently reported third family member, STAG3, is germinal cell-specific and is a subunit of the ...

Coordinates of the Absorption Capacity of Structural and Cohesion Funds at EU Level

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Anca Simina POPESCU

2015-09-01

Full Text Available The structural and cohesion funds are considered an attractive instrument for the funding of investments opportunities especially in times of crisis when the private investments are reduced. Nevertheless, they have not been factually highlighted in order to empirically document the role of European funds in supporting the short-term economic growth, at macroeconomic level. The target of absorbing as much European financial non-refundable aid requires constant efforts made by the member states and administration authorities, the involvement of regional and local public administrations in each stage of the process, as well as an appropriate capacity of institutional structures and management and control systems, they being basic premises of this objective achievement.

Marital conflict typology and children's appraisals: the moderating role of family cohesion.

Science.gov (United States)

Lindahl, Kristin M; Malik, Neena M

2011-04-01

Intense and frequent marital conflict is associated with greater appraisals of threat and self-blame in children, but little else is known about contextual factors that might affect appraisals. Systemic family theories propose that to understand child adaptation, it is necessary to understand the interconnected nature of family subsystem relationships. In a sample of 257 families with 8- to 12-year-old children, this study examined whether a four-level typology of marital conflict management was related to children's perceptions of marital conflict and their appraisals of perceived threat and self-blame. In addition, family cohesion was tested as a moderator of the relationship between marital conflict style and children's appraisals. Observational coding was used to group couples into Harmonious, Disengaged, Conflictual-Expressive, and Conflictual-Hostile groups. Children's report of the intensity, frequency, and degree of resolution of interparental discord corresponded well with observers' ratings. The relationship between marital conflict style and appraisals of threat and self-blame was moderated by family cohesiveness. At high levels of family cohesiveness, no group differences were found for either perceived threat or self-blame, whereas when family cohesiveness was low, threat was higher for the Harmonious and Conflictual-Hostile groups, as compared to the Conflictual-Expressive group, and self-blame was higher for both conflict groups (expressive and hostile), as compared to the Disengaged group. The results provide further evidence of interconnected nature of family subsystem relationships and the importance of distinguishing among different approaches to marital conflict management for understanding the complex and perhaps subtle but meaningful effects different family system factors have on child adaptation.

Improving decision speed, accuracy and group cohesion through early information gathering in house-hunting ants.

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Nathalie Stroeymeyt

Full Text Available BACKGROUND: Successful collective decision-making depends on groups of animals being able to make accurate choices while maintaining group cohesion. However, increasing accuracy and/or cohesion usually decreases decision speed and vice-versa. Such trade-offs are widespread in animal decision-making and result in various decision-making strategies that emphasize either speed or accuracy, depending on the context. Speed-accuracy trade-offs have been the object of many theoretical investigations, but these studies did not consider the possible effects of previous experience and/or knowledge of individuals on such trade-offs. In this study, we investigated how previous knowledge of their environment may affect emigration speed, nest choice and colony cohesion in emigrations of the house-hunting ant Temnothorax albipennis, a collective decision-making process subject to a classical speed-accuracy trade-off. METHODOLOGY/PRINCIPAL FINDINGS: Colonies allowed to explore a high quality nest site for one week before they were forced to emigrate found that nest and accepted it faster than emigrating naïve colonies. This resulted in increased speed in single choice emigrations and higher colony cohesion in binary choice emigrations. Additionally, colonies allowed to explore both high and low quality nest sites for one week prior to emigration remained more cohesive, made more accurate decisions and emigrated faster than emigrating naïve colonies. CONCLUSIONS/SIGNIFICANCE: These results show that colonies gather and store information about available nest sites while their nest is still intact, and later retrieve and use this information when they need to emigrate. This improves colony performance. Early gathering of information for later use is therefore an effective strategy allowing T. albipennis colonies to improve simultaneously all aspects of the decision-making process--i.e. speed, accuracy and cohesion--and partly circumvent the speed-accuracy trade

Does decentralisation enhance a school's role of promoting social cohesion? Bosnian school leaders' perceptions of school governance

Science.gov (United States)

Komatsu, Taro

2014-05-01

This study seeks to understand whether and how decentralised school governance in Bosnia and Herzegovina (BiH) enhances the schools' role of promoting social cohesion. This includes increasing "horizontal" trust among different ethnic groups and "vertical" trust between civilians and public institutes. The study examined secondary school leaders' perceptions regarding school board influence on social cohesion policies and practices, their interactions with school board members, and their accountability to the school-based governing body. The results show that school leaders and school boards, supposedly representing the interests of local stakeholders, did not appear to be actively engaged in the deliberate process of promoting social cohesion. While school directors tended to view themselves as being independent from the school boards, ethnically diverse school boards provided important support to proactive school leaders for their inter-group activities. Given that the central level is not providing initiatives to promote social cohesion and that BiH citizens appear to generally support social cohesion, decentralised school governance has the potential to improve social trust from the bottom up. To promote participatory school governance, the study recommends that BiH school leaders should be provided with opportunities to re-examine and redefine their professional accountability and to assist local stakeholders to improve their involvement in school governance.

Spatializing Open Data for the Assessment and the Improvement of Territorial and Social Cohesion

Science.gov (United States)

Scorza, F.; Las Casas, G. B.; Murgante, B.

2016-09-01

An integrated place-based approach for the improvement of territorial and social cohesion is the new instance for planning disciplines, coming from EU New Cohesion Policies. This paper considers the territorial impact assessment of regional development policies as a precondition in order to develop balanced and effective operative programs at national and regional levels. The contribution of `open data' appears to be mature in order to support this application and in this paper we present a spatial analysis technique for the evaluation of EU funds effects at territorial level, starting from open data by Open Cohesion. The application is focused on internal areas of Basilicata Region: Agri river Valley. A complex contest, where environmental and agricultural traditional vocations conflict with a recent development of oil extraction industries. Conclusions concern further applications and perspectives to improve and support regional development planning considering the exploitation of open data sources and spatial analysis.

Numerical simulation of cracks and interfaces with cohesive zone models in the extended finite element method, with EDF R and D software Code Aster

International Nuclear Information System (INIS)

Ferte, Guilhem

2014-01-01

In order to assess the harmfulness of detected defects in some nuclear power plants, EDF Group is led to develop advanced simulation tools. Among the targeted mechanisms are 3D non-planar quasi-static crack propagation, but also dynamic transients during unstable phases. In the present thesis, quasi-brittle crack growth is simulated based on the combination of the XFEM and cohesive zone models. These are inserted over large potential crack surfaces, so that the cohesive law will naturally separate adherent and de-bonding zones, resulting in an implicit update of the crack front, which makes the originality of the approach. This requires a robust insertion of non-smooth interface laws in the XFEM, which is achieved in quasi-statics with the use of XFEM-suited multiplier spaces in a consistent formulation, block-wise diagonal interface operators and an augmented Lagrangian formalism to write the cohesive law. Based on this concept and a novel directional criterion appealing to cohesive integrals, a propagation procedure over non-planar crack paths is proposed and compared with literature benchmarks. As for dynamics, an initially perfectly adherent cohesive law is implicitly treated within an explicit time-stepping scheme, resulting in an analytical determination of interface tractions if appropriate discrete spaces are used. Implementation is validated on a tapered DCB test. Extension to quadratic elements is then investigated. For stress-free cracks, it was found that a subdivision into quadratic sub-cells is needed for optimality. Theory expects enriched quadrature to be necessary for distorted sub-cells, but this could not be observed in practice. For adherent interfaces, a novel discrete multiplier space was proposed which has both numerical stability and produces quadratic convergence if used along with quadratic sub-cells. (author)

Neighborhoods and Mental Health: Exploring Ethnic Density, Poverty, and Social Cohesion among Asian Americans and Latinos

Science.gov (United States)

Hong, Seunghye; Zhang, Wei; Walton, Emily

2014-01-01

This study examines the associations of neighborhood ethnic density and poverty with social cohesion and self-rated mental health among Asian Americans and Latinos. Path analysis is employed to analyze data from the 2002–2003 National Latino and Asian American Study (NLAAS) and the 2000 U.S. Census (N=2095 Asian Americans living in N=259 neighborhoods; N=2554 Latinos living in N=317 neighborhoods). Findings reveal that neighborhood ethnic density relates to poor mental health in both groups. Social cohesion partially mediates that structural relationship, but is positively related to ethnic density among Latinos and negatively related to ethnic density among Asian Americans. Although higher neighborhood poverty is negatively associated with mental health for both groups, the relationship does not hold in the path models after accounting for social cohesion and covariates. Furthermore, social cohesion fully mediates the association between neighborhood poverty and mental health among Latinos. This study highlights the necessity of reconceptualizing existing theories of social relationships to reflect complex and nuanced mechanisms linking neighborhood structure and mental health for diverse racial and ethnic groups. PMID:24769491

Simulation study of the discharge characteristics of silos with cohesive particles

Science.gov (United States)

Hund, David; Weis, Dominik; Hesse, Robert; Antonyuk, Sergiy

2017-06-01

In many industrial applications the silo for bulk materials is an important part of an overall process. Silos are used for instance to buffer intermediate products to ensure a continuous supply for the next process step. This study deals with the discharging behaviour of silos containing cohesive bulk solids with particle sizes in the range of 100-500 μm. In this contribution the TOMAS [1,2] model developed for stationary and non-stationary discharging of a convergent hopper is verified with experiments and simulations using the Discrete Element Method. Moreover the influence of the cohesion of the bulk solids on the discharge behaviour is analysed by the simulation. The simulation results showed a qualitative agreement with the analytical model of TOMAS.

The Relationship between Task Cohesion and Competitive State Anxiety.

Science.gov (United States)

Eys, Mark A.; Hardy, James; Carron, Albert V.; Beauchamp, Mark R.

2003-01-01

Examined the association between athlete perceptions of task cohesiveness (Individual Attractions to the Group-Task and Group Integration-Task) and the degree to which they viewed their perceptions of the presence of pre-competition anxiety symptoms as facilitative or debilitative. Survey data indicated that the more positive their perceptions of…

Active cell-matrix coupling regulates cellular force landscapes of cohesive epithelial monolayers

Science.gov (United States)

Zhao, Tiankai; Zhang, Yao; Wei, Qiong; Shi, Xuechen; Zhao, Peng; Chen, Long-Qing; Zhang, Sulin

2018-03-01

Epithelial cells can assemble into cohesive monolayers with rich morphologies on substrates due to competition between elastic, edge, and interfacial effects. Here we present a molecularly based thermodynamic model, integrating monolayer and substrate elasticity, and force-mediated focal adhesion formation, to elucidate the active biochemical regulation over the cellular force landscapes in cohesive epithelial monolayers, corroborated by microscopy and immunofluorescence studies. The predicted extracellular traction and intercellular tension are both monolayer size and substrate stiffness dependent, suggestive of cross-talks between intercellular and extracellular activities. Our model sets a firm ground toward a versatile computational framework to uncover the molecular origins of morphogenesis and disease in multicellular epithelia.

Psychobiological Assessment and Enhancement of Team Cohesion and Psychological Resilience in ROTC Cadets Using a Virtual-Reality Team Cohesion Test

Science.gov (United States)

2017-06-01

processing and transcribing of audio recordings. This audio data will provide measures of group cohesion, group roles , communication efficiency, etc. 4...or other products from the project made an impact or are likely to make an impact on the base of knowledge, theory , and research in the principal...Recruitment and Retention: Thus far, recruitment has consisted of civilians. We are recruiting both male and female same- sex triads. Recruitment

Cohesion-Induced Stabilization in Stick-Slip Dynamics of Weakly Wet, Sheared Granular Fault Gouge

Science.gov (United States)

Dorostkar, Omid; Guyer, Robert A.; Johnson, Paul A.; Marone, Chris; Carmeliet, Jan

2018-03-01

We use three-dimensional discrete element calculations to study stick-slip dynamics in a weakly wet granular layer designed to simulate fault gouge. The granular gouge is constituted by 8,000 spherical particles with a polydisperse size distribution. At very low liquid content, liquids impose cohesive and viscous forces on particles. Our simulations show that by increasing the liquid content, friction increases and granular layer shows higher recurrence time between slip events. We also observe that slip events exhibit larger friction drop and layer compaction in wet system compared to dry. We demonstrate that a small volume of liquid induces cohesive forces between wet particles that are responsible for an increase in coordination number leading to a more stable arrangement of particles. This stabilization is evidenced with 2 orders of magnitude lower particle kinetic energy in wet system during stick phase. Similar to previous experimental studies, we observe enhanced frictional strength for wet granular layers. In experiments, the physicochemical processes are believed to be the main reason for such behavior; we show, however, that at low confining stresses, the hydromechanical effects of induced cohesion are sufficient for observed behavior. Our simulations illuminate the role of particle interactions and demonstrate the conditions under which induced cohesion plays a significant role in fault zone processes, including slip initiation, weakening, and failure.

Alkaline DNA fragmentation, DNA disentanglement evaluated viscosimetrically and sister chromatid exchanges, after treatment in vivo with nitrofurantoin.

Science.gov (United States)

Parodi, S; Pala, M; Russo, P; Balbi, C; Abelmoschi, M L; Taningher, M; Zunino, A; Ottaggio, L; de Ferrari, M; Carbone, A; Santi, L

1983-07-01

Nitrofurantoin was not positive as a carcinogen in long term assays. In vitro it was positive in some short term tests and negative in others. We have examined Nitrofurantoin for its capability of inducing DNA damage in vivo. With the alkaline elution technique, Nitrofurantoin appeared clearly positive in all the tissues examined (liver, kidney, lung, spleen and bone marrow). In the liver we also observed some cross-linking effect. In bone marrow cells Nitrofurantoin was also clearly positive in terms of sister chromatid exchanges (SCEs) induction. DNA damage in vivo was also examined with a viscosimetric method, more sensitive than alkaline elution. With this method the results were essentially negative, suggesting that the two methods detect different types of damage. In view of its positivity in many organs and in two short term tests in vivo, the carcinogenic potential of Nitrofurantoin should be reconsidered.

DNA Packaging Specificity of Bacteriophage N15 with an Excursion into the Genetics of a Cohesive End Mismatch.

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Michael Feiss

Full Text Available During DNA replication by the λ-like bacteriophages, immature concatemeric DNA is produced by rolling circle replication. The concatemers are processed into mature chromosomes with cohesive ends, and packaged into prohead shells, during virion assembly. Cohesive ends are generated by the viral enzyme terminase, which introduces staggered nicks at cos, an approx. 200 bp-long sequence containing subsites cosQ, cosN and cosB. Interactions of cos subsites of immature concatemeric DNA with terminase orchestrate DNA processing and packaging. To initiate DNA packaging, terminase interacts with cosB and nicks cosN. The cohesive ends of N15 DNA differ from those of λ at 2/12 positions. Genetic experiments show that phages with chromosomes containing mismatched cohesive ends are functional. In at least some infections, the cohesive end mismatch persists through cyclization and replication, so that progeny phages of both allelic types are produced in the infected cell. N15 possesses an asymmetric packaging specificity: N15 DNA is not packaged by phages λ or 21, but surprisingly, N15-specific terminase packages λ DNA. Implications for genetic interactions among λ-like bacteriophages are discussed.

Evidence for contact calls in fish: conspecific vocalisations and ambient soundscape influence group cohesion in a nocturnal species

Science.gov (United States)

van Oosterom, L.; Montgomery, J. C.; Jeffs, A. G.; Radford, C. A.

2016-01-01

Soundscapes provide a new tool for the study of fish communities. Bigeyes (Pempheris adspersa) are nocturnal planktivorous reef fish, feed in loose shoals and are soniferous. These vocalisations have been suggested to be contact calls to maintain group cohesion, however direct evidence for this is absent, despite the fact that contact calls are well documented for many other vertebrates, including marine mammals. For fish, direct evidence for group cohesion signals is restricted to the use of visual and hydrodynamic cues. In support of adding vocalisation as a contributing cue, our laboratory experiments show that bigeyes significantly increased group cohesion when exposed to recordings of ambient reef sound at higher sound levels while also decreasing vocalisations. These patterns of behaviour are consistent with acoustic masking. When exposed to playback of conspecific vocalisations, the group cohesion and vocalisation rates of bigeyes both significantly increased. These results provide the first direct experimental support for the hypotheses that vocalisations are used as contact calls to maintain group cohesion in fishes, making fish the evolutionarily oldest vertebrate group in which this phenomenon has been observed, and adding a new dimension to the interpretation of nocturnal reef soundscapes.

Sister chromatid exchanges and structural chromosome aberrations in lymphocytes in operating room personnel

Energy Technology Data Exchange (ETDEWEB)

Husum, B; Niebuhr, E; Wulf, H C; Norgaard, I

1983-06-01

Information on possible chromosomal damage in humans after long-term exposure to trace concentrations of waste anaesthetic gases is scarce. We examined peripheral lymphocytes in operating room personnel for both chromosome aberrations and sister chromatid exchanges (SCE). Following a standardized procedure of cultivation and staining, 30 cells from each person were scored for SCE and 100 cells from each person were examined for chromosome aberrations. A total of 45 persons were examined, representing anaesthetists (n . 15), operating room nurses assisting the surgeon (n . 10), nurses circulating in the operating room (n . 8) and healthy, unexposed controls (n . 12). The median duration of working in the operating room was 102 months, respectively. Time-weighted concentration levels of 2.5-4.3 p.p.m. of halothane and 25-400 p.p.m. of nitrous oxide were measured in the breathing zones of the anaesthetists during mask anaesthesia. Examination of SCE and chromosome aberrations yielded corresponding qualitative results. With both tests, no statistically significant difference was observed between the four groups of persons. It was concluded that by examination of both SCE and chromosome aberrations in peripheral lymphocytes in operating room personnel, no indication was found of a mutagenic effect of long-term exposure to trace concentrations of waste anaesthetic gases.

Bothered by abstractness or engaged by cohesion? Experts' explanations enhance novices' deep-learning.

Science.gov (United States)

Lachner, Andreas; Nückles, Matthias

2015-03-01

Experts' explanations have been shown to better enhance novices' transfer as compared with advanced students' explanations. Based on research on expertise and text comprehension, we investigated whether the abstractness or the cohesion of experts' and intermediates' explanations accounted for novices' learning. In Study 1, we showed that the superior cohesion of experts' explanations accounted for most of novices' transfer, whereas the degree of abstractness did not impact novices' transfer performance. In Study 2, we investigated novices' processing while learning with experts' and intermediates' explanations. We found that novices studying experts' explanations actively self-regulated their processing of the explanations, as they showed mainly deep-processing activities, whereas novices learning with intermediates' explanations were mainly engaged in shallow-processing activities by paraphrasing the explanations. Thus, we concluded that subject-matter expertise is a crucial prerequisite for instructors. Despite the abstract character of experts' explanations, their subject-matter expertise enables them to generate highly cohesive explanations that serve as a valuable scaffold for students' construction of flexible knowledge by engaging them in deep-level processing. PsycINFO Database Record (c) 2015 APA, all rights reserved.

Resolving RAD51C function in late stages of homologous recombination

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Kuznetsov Sergey G

2007-06-01

Full Text Available Abstract DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange between homologous DNA. Although various resolvases with Holliday junctions processing activity have been identified in bacteriophages, bacteria and archaebacteria, eukaryotic resolvases have been elusive. Recent biochemical evidence has revealed that RAD51C and XRCC3, members of the RAD51-like protein family, are involved in Holliday junction resolution in mammalian cells. However, purified recombinant RAD51C and XRCC3 proteins have not shown any Holliday junction resolution activity. In addition, these proteins did not reveal the presence of a nuclease domain, which raises doubts about their ability to function as a resolvase. Furthermore, oocytes from infertile Rad51C mutant mice exhibit precocious separation of sister chromatids at metaphase II, a phenotype that reflects a defect in sister chromatid cohesion, not a lack of Holliday junction resolution. Here we discuss a model to explain how a Holliday junction resolution defect can lead to sister chromatid separation in mouse oocytes. We also describe other recent in vitro and in vivo evidence supporting a late role for RAD51C in homologous recombination in mammalian cells, which is likely to be resolution of the Holliday junction.

Meikin-associated polo-like kinase specifies Bub1 distribution in meiosis I.

Science.gov (United States)

Miyazaki, Seira; Kim, Jihye; Yamagishi, Yuya; Ishiguro, Tadashi; Okada, Yuki; Tanno, Yuji; Sakuno, Takeshi; Watanabe, Yoshinori

2017-06-01

In meiosis I, sister chromatids are captured by microtubules emanating from the same pole (mono-orientation), and centromeric cohesion is protected throughout anaphase. Shugoshin, which is localized to centromeres depending on the phosphorylation of histone H2A by Bub1 kinase, plays a central role in protecting meiotic cohesin Rec8 from separase cleavage. Another key meiotic kinetochore factor, meikin, may regulate cohesion protection, although the underlying molecular mechanisms remain elusive. Here, we show that fission yeast Moa1 (meikin), which associates stably with CENP-C during meiosis I, recruits Plo1 (polo-like kinase) to the kinetochores and phosphorylates Spc7 (KNL1) to accumulate Bub1. Consequently, in contrast to the transient kinetochore localization of mitotic Bub1, meiotic Bub1 persists at kinetochores until anaphase I. The meiotic Bub1 pool ensures robust Sgo1 (shugoshin) localization and cohesion protection at centromeres by cooperating with heterochromatin protein Swi6, which binds and stabilizes Sgo1. Furthermore, molecular genetic analyses show a hierarchical regulation of centromeric cohesion protection by meikin and shugoshin that is important for establishing meiosis-specific chromosome segregation. We provide evidence that the meiosis-specific Bub1 regulation is conserved in mouse. © 2017 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Coach-Initiated Motivational Climate and Cohesion in Youth Sport

Science.gov (United States)

Eys, Mark A.; Jewitt, Eryn; Evans, M. Blair; Wolf, Svenja; Bruner, Mark W.; Loughead, Todd M.

2013-01-01

Purpose: The general purpose of the present study was to examine the link between cohesion and motivational climate in youth sport. The first specific objective was to determine if relationships demonstrated in previous research with adult basketball and handball participants would be replicated in a younger sample and with a more heterogeneous…

Cohesive Errors in Writing among ESL Pre-Service Teachers

Science.gov (United States)

Kwan, Lisa S. L.; Yunus, Melor Md

2014-01-01

Writing is a complex skill and one of the most difficult to master. A teacher's weak writing skills may negatively influence their students. Therefore, reinforcing teacher education by first determining pre-service teachers' writing weaknesses is imperative. This mixed-methods error analysis study aims to examine the cohesive errors in the writing…

Investigation into process-induced de-aggregation of cohesive micronised API particles.

Science.gov (United States)

Hoffmann, Magnus; Wray, Patrick S; Gamble, John F; Tobyn, Mike

2015-09-30

The aim of this study was to assess the impact of unit processes on the de-aggregation of a cohesive micronised API within a pharmaceutical formulation using near-infrared chemical imaging. The impact on the primary API particles was also investigated using an image-based particle characterization system with integrated Raman analysis. The blended material was shown to contain large, API rich domains which were distributed in-homogeneously across the sample, suggesting that the blending process was not aggressive enough to disperse aggregates of micronised drug particles. Cone milling, routinely used to improve the homogeneity of such cohesive formulations, was observed to substantially reduce the number and size of API rich domains; however, several smaller API domains survived the milling process. Conveyance of the cone milled formulation through the Alexanderwerk WP120 powder feed system completely dispersed all remaining aggregates. Importantly, powder feed transmission of the un-milled formulation was observed to produce an equally homogeneous API distribution. The size of the micronised primary drug particles remained unchanged during powder feed transmission. These findings provide further evidence that this powder feed system does induce shear, and is in fact better able to disperse aggregates of a cohesive micronised API within a blend than the blend-mill-blend step. Crown Copyright © 2015. Published by Elsevier B.V. All rights reserved.

A consistent partly cracked XFEM element for cohesive crack growth

DEFF Research Database (Denmark)

Asferg, Jesper L.; Poulsen, Peter Noe; Nielsen, Leif Otto

2007-01-01

Present extended finite element method (XFEM) elements for cohesive crack growth may often not be able to model equal stresses on both sides of the discontinuity when acting as a crack-tip element. The authors have developed a new partly cracked XFEM element for cohesive crack growth with extra...... enrichments to the cracked elements. The extra enrichments are element side local and were developed by superposition of the standard nodal shape functions for the element and standard nodal shape functions for a sub-triangle of the cracked element. With the extra enrichments, the crack-tip element becomes...... capable of modelling variations in the discontinuous displacement field on both sides of the crack and hence also capable of modelling the case where equal stresses are present on each side of the crack. The enrichment was implemented for the 3-node constant strain triangle (CST) and a standard algorithm...

Social cohesion, social support, and health among Latinos in the United States.

Science.gov (United States)

Mulvaney-Day, Norah E; Alegría, Margarita; Sribney, William

2007-01-01

The role of individual versus community level social connections in promoting health is an important factor to consider when addressing Latino health. This analysis examines the relationships between social support, social cohesion, and health in a sample of Latinos in the United States. Using data from the National Latino and Asian American Study, the analysis uses ordered logistic regression to explore the relationships of family support, friend support, family cultural conflict, and neighborhood social cohesion with self-rated physical and mental health, taking into account language proficiency and use, nativity, and sociodemographic variables. Family support, friend support, and neighborhood social cohesion were positively related to self-rated physical and mental health, and family cultural conflict was negatively related when controlled only for sex and age. After controlling for education, income, and other demographic measures, only family support was found to have a weak association with self-rated physical health; however, the relationship seemed to be mediated by language. In contrast, family support and family cultural conflict were strongly associated with self-rated mental health, after controlling for language, education, income, and other demographic measures. The study did not find neighborhood social cohesion to be significantly related to either self-rated physical or mental health, after accounting for the effects of the other social connection variables. Language of interview did not explain the highly significant effects of language proficiency and use. Social connections are important for health and mental health, but language and other sociodemographic factors seem to be related to how Latinos establish these social linkages. Further investigation into the role of language in the development and maintenance of social connections may help unravel the mechanisms by which they promote or decrease health.

Towards an integrated approach to cohesion and coherence in ...

African Journals Online (AJOL)

The notions of cohesion and coherence have a long tradition in the linguistic literature. They date back to ancient .... syntax, and operates in short-term or working memory. Coherence is related to the ..... account of all the elements that occur in the film, namely, words, gestures, images, music and sound effects. In other ...

The application of J integral to measure cohesive laws in materials undergoing large scale yielding

DEFF Research Database (Denmark)

Sørensen, Bent F.; Goutianos, Stergios

2015-01-01

We explore the possibility of determining cohesive laws by the J-integral approach for materials having non-linear stress-strain behaviour (e.g. polymers and composites) by the use of a DCB sandwich specimen, consisting of stiff elastic beams bonded to the non-linear test material, loaded with pure...... bending moments. For a wide range of parameters of the non-linear material, the plastic unloading during crack extension is small, resulting in J integral values (fracture resistance) that deviate maximum 15% from the work of the cohesive traction. Thus the method can be used to extract the cohesive laws...... directly from experiments without any presumption about their shape. Finally, the DCB sandwich specimen was also analysed using the I integral to quantify the overestimation of the steady-state fracture resistance obtained using the J integral based method....

Moisture Content Impact on Mechanical Properties of Selected Cohesive Soils from the Wielkopolskie Voivodeship Southern Part

Directory of Open Access Journals (Sweden)

Pezowicz Piotr

2015-12-01

Full Text Available Results of investigations of shearing resistance and compressibility of fine-grained cohesive soil from the southern part of the wielkopolskie voivodeship in relation to the increasing moisture content are presented. The analysis of two series of samples, using soil paste for the consistency index of 0.9 and 0.4–0.3 was carried out. The results imply that the increasing moisture content causes a decrease in the angle of shearing resistance and cohesion and is also reflected in the higher compressibility of the soil. It was observed that regardless of the soil consistency, the angle of shearing resistance decreases and the cohesion value and the oedometric modulus of primary (consolidation and secondary compressibility grows with the increase in the clay fraction.

NON-COHESIVE SOILS’ COMPRESSIBILITY AND UNEVEN GRAIN-SIZE DISTRIBUTION RELATION

Directory of Open Access Journals (Sweden)

Anatoliy Mirnyy

2016-03-01

Full Text Available This paper presents the results of laboratory investigation of soil compression phases with consideration of various granulometric composition. Materials and Methods Experimental soil box with microscale video recording for compression phases studies is described. Photo and video materials showing the differences of microscale particle movements were obtained for non-cohesive soils with different grain-size distribution. Results The analysis of the compression tests results and elastic and plastic deformations separation allows identifying each compression phase. It is shown, that soil density is correlating with deformability parameters only for the same grain-size distribution. Basing on the test results the authors suggest that compaction ratio is not sufficient for deformability estimating without grain-size distribution taken into account. Discussion and Conclusions Considering grain-size distribution allows refining technological requirements for artificial soil structures, backfills, and sand beds. Further studies could be used for developing standard documents, SP45.13330.2012 in particular.

Improving the geotechnical behavior of sand through cohesive admixtures

Directory of Open Access Journals (Sweden)

Mohie eldin Mohamed Afify Elmashad

2018-04-01

Full Text Available Irrigation projects in Egypt have been facing tremendous challenges, mostly is the scarcity of irrigation water. The current research presents the effect of different cohesive admixture on the conductivity of siliceous sand in general and its other geotechnical properties. Two different types of conventional swelling clay from (Toshka, 6th of October as well as bentonite were used to construct the irrigation canals and embankment. The results indicated that increase in the plasticity properties of the treated soil also decrease the permeability and infiltration. Moreover, the dry density of 2.08 t/m3 was obtained from sand and 20% 6th of October mixture, also the CBR of 31.20% were obtained from sand and 8% 6th of October mixture. Increasing the bentonite ratio increases the cohesion and decreasing the permeability. The swelling ratios of sand 6th of October Clay mixture is equal to 0.28%, and the fictitious stress at which the swelling ratio is nil, is equal to 16 kPa. Keywords: Sand, Swelling clay, Bentonite, Compaction test, Consolidation test, Triaxial test

An enriched cohesive zone model for delamination in brittle interfaces

NARCIS (Netherlands)

Samimi, M.; Dommelen, van J.A.W.; Geers, M.G.D.

2009-01-01

Application of standard cohesive zone models in a finite element framework to simulate delamination in brittle interfaces may trigger non-smooth load-displacement responses that lead to the failure of iterative solution procedures. This non-smoothness is an artifact of the discretization; and hence

Team cohesion and ethnic-cultural identity in adolescent migrant athletes

NARCIS (Netherlands)

Morela, Eleftheria; Hatzigeorgiadis, Antonis; Kouli, Olga; Elbe, Anne-Marie; Sanchez, Xavier

The purpose of this study was to examine the role of sport participation in the social integration of adolescents with non-dominant ethnic and cultural backgrounds. In particular, this study investigated the relationship between team cohesion and ethnic-cultural identity. Participants were 83 young

Evolution of Perceived Cohesion and Efficacy over the Season and their Relation to Success Expectations in Soccer Teams.

Science.gov (United States)

Marcos, Francisco Miguel Leo; Sánchez-Miguel, Pedro Antonio; Sánchez-Oliva, David; Alonso, Diana Amado; García-Calvo, Tomás

2012-10-01

The main goal of the study is to examine the evolution of players' perception of cohesion and efficacy over the season and their relation with success expectations. The research sample comprised 146 male soccer players, aged between 15 and 19 years (M = 16.96, SD = .76). Diverse instruments were used to measure cohesion, perceived efficacy, and success expectations. The most noteworthy results show that players whose expectations do not match the team's final performance will experience a negative evolution of their levels of perceived cohesion and efficacy, whereas players whose expectations at the start of the season match the team's final performance in the classification will maintain their degree of perceived cohesion and efficacy. The main conclusion of the study is that coaches and sport psychologists should attempt to clarify the players' basic goals of the season to create expectations that match what is expected from the team.

Contribution of the EU Budget to the Implementation of the Social Cohesion Policy of the European Union

Directory of Open Access Journals (Sweden)

Katarzyna Stabryła-Chudzio

2016-04-01

Full Text Available Objective: The aim of the present study is to examine whether the European Union budget comprises significant resources for financing measures relating to social cohesion. The analysis is based on the contents of the Europe 2020 Strategy. Given the constraints of space and for the sake of clarity of the argument, the author focuses on the role of the EU budget rather than all measures aimed at social cohesion undertaken by EU institutions or targeted by policies of individual Member States.Methodology: Documents, studies and reports published by the European Commission constitute the main source of information. In addition, the author has taken into account macroeconomic data demonstrating the deterioration of the social situation since 2009, as well as the instruments that the European Commission has deployed since 2013 in order to respond to post-crisis challenges.Conclusions: It can be roughly estimated that more than 40 percent of total resources within the Multiannual Financial Framework 2014–2020 shall be allocated to the social cohesion policy. Opportunities afforded by the implementation of the Europe 2020 Strategy include primarily the definition of objectives whose priority is indisputable and the introduction of the hitherto neglected analysis of certain socio-economic indicators, classified by country or region and, in certain cases, examined in more detail than required by the European Commission. The monitoring of objectives is conducive to the introduction of new solutions and implementation tools, as exemplified by the new instruments within the Multiannual Financial Framework 2014–2020, as well as the adjustment of available funds in light of the most pressing challenges. The European Semester has facilitated the task of comparing progress in strategy implementation by individual Member States, as well as the provision of recommendations for each of them and an individualized approach.Research implications: This article

Facilitating or hindering social cohesion? The impact of the ...

African Journals Online (AJOL)

However, we show in this article that that the impact of the CWP is not always positive and that the CWP may in some cases result in tensions and contradictions that hinder social cohesion and even cause violence. If not implemented in a consultative participatory manner, the CWP may be a source of conflict rather than of ...

Guidelines for Applying Cohesive Models to the Damage Behaviour of Engineering Materials and Structures

CERN Document Server

Schwalbe, Karl-Heinz; Cornec, Alfred

2013-01-01

This brief provides guidance for the application of cohesive models to determine damage and fracture in materials and structural components. This can be done for configurations with or without a pre-existing crack. Although the brief addresses structural behaviour, the methods described herein may also be applied to any deformation induced material damage and failure, e.g. those occurring during manufacturing processes. The methods described are applicable to the behaviour of ductile metallic materials and structural components made thereof. Hints are also given for applying the cohesive model to other materials.

Method and apparatus for blending fine and cohesive powders in a fluidized bed with gas injection through ball valves

International Nuclear Information System (INIS)

1981-01-01

A fluidized bed blender is described, suitable for blending powders including a mixture of fine and cohesive powders and in particular for converting a heterogeneous mixture of fine and cohesive UO 2 into a homogeneous mixture. (U.K.)

Increased alcohol use after Hurricane Ike: The roles of perceived social cohesion and social control.

Science.gov (United States)

Ma, Chenyi; Smith, Tony E

2017-10-01

Hurricane Ike, the third costliest hurricane in US history, made landfall in the Galveston Bay Area in September, 2008. Existing literature postulates that maladaptive behavior such as increased alcohol use is often exhibited by disaster survivors in coping with both disaster-related traumatic events and post-disaster stressful events. In addition, it has also been postulated that survivors' perceptions of social cohesion and social control can potentially serve to moderate such behavior. The purpose of this paper is to study such hypotheses for Hurricane Ike. In particular, we investigate the following four hypotheses: (H1) There is an increase of alcohol use by survivors of Hurricane Ike in the Galveston Bay Area; (H2) There are positive associations between both Ike-related trauma and post-Ike stress events and the increase in alcohol use; (H3) There are negative associations between both perceived social cohesion and social control and the increase in alcohol use following Ike; and finally that (H4) perceived social cohesion and social control serve to moderate the associations between both Ike-related trauma and post-Ike stress events and increased alcohol use after Ike. Using public use survey-weighted data from the Galveston Bay Recovery Study (GBRS) of Ike survivors (N = 658), we tested these hypotheses using logistic regressions controlling for other key socioeconomic variables. Our results confirm H1 and H2. Hypotheses H3 and H4 are partially confirmed with respect to social control, but show that (i) there is a positive association between perceived social cohesion and the increase in alcohol use following Ike, and that (ii) while perceived social cohesion and social control do moderate the association between post-Ike stress events and increased alcohol use, they have no effect on the association between Ike-related trauma and increased alcohol use. Copyright © 2017 Elsevier Ltd. All rights reserved.

Optimisation Of Process Parameters In High Energy Mixing As A Method Of Cohesive Powder Flowability Improvement

Directory of Open Access Journals (Sweden)

Leś Karolina

2015-12-01

Full Text Available Flowability of fine, highly cohesive calcium carbonate powder was improved using high energy mixing (dry coating method consisting in coating of CaCO3 particles with a small amount of Aerosil nanoparticles in a planetary ball mill. As measures of flowability the angle of repose and compressibility index were used. As process variables the mixing speed, mixing time, and the amount of Aerosil and amount of isopropanol were chosen. To obtain optimal values of the process variables, a Response Surface Methodology (RSM based on Central Composite Rotatable Design (CCRD was applied. To match the RSM requirements it was necessary to perform a total of 31 experimental tests needed to complete mathematical model equations. The equations that are second-order response functions representing the angle of repose and compressibility index were expressed as functions of all the process variables. Predicted values of the responses were found to be in a good agreement with experimental values. The models were presented as 3-D response surface plots from which the optimal values of the process variables could be correctly assigned. The proposed, mechanochemical method of powder treatment coupled with response surface methodology is a new, effective approach to flowability of cohesive powder improvement and powder processing optimisation.

Effect of crystal habits on the surface energy and cohesion of crystalline powders.

Science.gov (United States)

Shah, Umang V; Olusanmi, Dolapo; Narang, Ajit S; Hussain, Munir A; Gamble, John F; Tobyn, Michael J; Heng, Jerry Y Y

2014-09-10

The role of surface properties, influenced by particle processing, in particle-particle interactions (powder cohesion) is investigated in this study. Wetting behaviour of mefenamic acid was found to be anisotropic by sessile drop contact angle measurements on macroscopic (>1cm) single crystals, with variations in contact angle of water from 56.3° to 92.0°. This is attributed to variations in surface chemical functionality at specific facets, and confirmed using X-ray photoelectron spectroscopy (XPS). Using a finite dilution inverse gas chromatography (FD-IGC) approach, the surface energy heterogeneity of powders was determined. The surface energy profile of different mefenamic acid crystal habits was directly related to the relative exposure of different crystal facets. Cohesion, determined by a uniaxial compression test, was also found to relate to surface energy of the powders. By employing a surface modification (silanisation) approach, the contribution from crystal shape from surface area and surface energy was decoupled. By "normalising" contribution from surface energy and surface area, needle shaped crystals were found to be ∼2.5× more cohesive compared to elongated plates or hexagonal cuboid shapes crystals. Copyright © 2014. Published by Elsevier B.V.

Cohesive motion in one-dimensional flocking

International Nuclear Information System (INIS)

Dossetti, V

2012-01-01

A one-dimensional rule-based model for flocking, which combines velocity alignment and long-range centering interactions, is presented and studied. The induced cohesion in the collective motion of the self-propelled agents leads to unique group behavior that contrasts with previous studies. Our results show that the largest cluster of particles, in the condensed states, develops a mean velocity slower than the preferred one in the absence of noise. For strong noise, the system also develops a non-vanishing mean velocity, alternating its direction of motion stochastically. This allows us to address the directional switching phenomenon. The effects of different sources of stochasticity on the system are also discussed. (paper)

Cohesive zone modelling and the fracture process of structural tape

DEFF Research Database (Denmark)

Stigh, Ulf; Biel, Anders; Svensson, Daniel

2016-01-01

and the separation is measured experimentally using methods based on the path independence of the J-integral. Repeated experiments are performed at quasi-static loading. A mixed mode cohesive law is adapted to the experimental data. The law is implemented as a UMAT in Abaqus. Simulations show minor thermal...

Fear, crime, and social cohesion in urban South Africa | IDRC ...

International Development Research Centre (IDRC) Digital Library (Canada)

2016-12-13

Dec 13, 2016 ... Social cohesion” broadly refers to the factors that hold a society ... published in March 2016, explores the role of social cohesion and ... Learn more about IDRC's research support to make cities safer through the Safe and Inclusive Cities partnership with the UK's Department for International Development.

Family Rituals and Quality of Life in Children With Cancer and Their Parents: The Role of Family Cohesion and Hope

Science.gov (United States)

Crespo, Carla; Canavarro, M. Cristina; Kazak, Anne E.

2015-01-01

Objective Family rituals are associated with adaptive functioning in pediatric illness, including quality of life (QoL). This article explores the role of family cohesion and hope as mediators of this association in children with cancer and their parents. Methods Portuguese children with cancer (N = 389), on- and off-treatment, and one of their parents completed self-report measures. Structural equation modeling was used to examine direct and indirect links between family rituals and QoL. Results When children and parents reported higher levels of family rituals, they also reported more family cohesion and hope, which were linked to better QoL. At the dyadic level, children’s QoL was related to parents’ family rituals through the child’s family cohesion. This model was valid across child’s age-group, treatment status, and socioeconomic status. Conclusions Family rituals are important in promoting QoL in pediatric cancer via family cohesion and hope individually and via family cohesion in terms of parent–child interactions. PMID:25775914

Calculation of passive earth pressure of cohesive soil based on Culmann's method

Directory of Open Access Journals (Sweden)

Hai-feng Lu

2011-03-01

Full Text Available Based on the sliding plane hypothesis of Coulumb earth pressure theory, a new method for calculation of the passive earth pressure of cohesive soil was constructed with Culmann's graphical construction. The influences of the cohesive force, adhesive force, and the fill surface form were considered in this method. In order to obtain the passive earth pressure and sliding plane angle, a program based on the sliding surface assumption was developed with the VB.NET programming language. The calculated results from this method were basically the same as those from the Rankine theory and Coulumb theory formulas. This method is conceptually clear, and the corresponding formulas given in this paper are simple and convenient for application when the fill surface form is complex.

Advantages and controversy of common agricultural and cohesion policy in the EU

Directory of Open Access Journals (Sweden)

Kostić Vladimir

2016-01-01

Full Text Available The authors explore deals and payments that have a positive effect on the development of Common agricultural and cohesion policy. They particularly emphasize the ways of protecting the European Union from cheap imported products from non-EU countries. They also deal with the mechanisms that are built into the process, with the structural policy regarding 'Agenda 2000', as well as the reforms of Common agricultural and cohesion policy from its beginnings until now. The paper presents problems of guaranteed prices, ecology, quotas, agricultural levies and customs duties. The authors also investigated the Common Agricultural and Rural Policy of the European Union 2014-2020, the ways to accelerate the transfer of technology and strengthen the cooperation between agriculture and research sectors in the future.

Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation.

Science.gov (United States)

Asghar, Adeel; Lajeunesse, Audrey; Dulla, Kalyan; Combes, Guillaume; Thebault, Philippe; Nigg, Erich A; Elowe, Sabine

2015-09-24

During mitosis, Bub1 kinase phosphorylates histone H2A-T120 to promote centromere sister chromatid cohesion through recruitment of shugoshin (Sgo) proteins. The regulation and dynamics of H2A-T120 phosphorylation are poorly understood. Using quantitative phosphoproteomics we show that Bub1 is autophosphorylated at numerous sites. We confirm mitosis-specific autophosphorylation of a several residues and show that Bub1 activation is primed in interphase but fully achieved only in mitosis. Mutation of a single autophosphorylation site T589 alters kinetochore turnover of Bub1 and results in uniform H2A-T120 phosphorylation and Sgo recruitment along chromosome arms. Consequently, improper sister chromatid resolution and chromosome segregation errors are observed. Kinetochore tethering of Bub1-T589A refocuses H2A-T120 phosphorylation and Sgo1 to centromeres. Recruitment of the Bub1-Bub3-BubR1 axis to kinetochores has recently been extensively studied. Our data provide novel insight into the regulation and kinetochore residency of Bub1 and indicate that its localization is dynamic and tightly controlled through feedback autophosphorylation.

Genre-dependent interaction of coherence and lexical cohesion in written discourse

NARCIS (Netherlands)

Berzlánovich, I.; Redeker, G.

2012-01-01

We investigate the interaction between coherence and lexical cohesion in expository and persuasive texts using seven encyclopedia texts and seven fundraising letters. We describe genre structure in terms of genre-specific moves and coherence structure with Rhetorical Structure Theory. For lexical

Family Cohesion, Adaptability and Composition in Adolescents from Callao, Peru

Science.gov (United States)

Villarreal-Zegarra, David; Paz-Jesús, Angel

2017-01-01

The objective of the study was to analyze if there are significant differences between family cohesion and adaptability according to the type of family composition (nuclear, extended, single parent and non-nuclear). This is a non-experimental and empirical research, in which a non-probabilistic, cross-sectional, selective and associative strategy…

Sense of Cohesion among Community Activists Engaging in Volunteer Activity

Science.gov (United States)

Levy, Drorit; Itzhaky, Haya; Zanbar, Lea; Schwartz, Chaya

2012-01-01

The present article attempts to shed light on the direct and indirect contribution of personal resources and community indices to Sense of Cohesion among activists engaging in community volunteer work. The sample comprised 481 activists. Based on social systems theory, three levels of variables were examined: (1) inputs, which included personal…

Impacts on the Social Cohesion of Mainland Spain’s Future Motorway and High-Speed Rail Networks

Directory of Open Access Journals (Sweden)

José Manuel Naranjo Gómez

2016-07-01

Full Text Available A great expansion of the road and rail network is contemplated in the Infrastructure, Transport and Housing Plan (PITVI in Spanish, in order to achieve greater social cohesion in 2024 in Spain. For this reason, the aim of this study is to classify and to identify those municipalities that are going to improve or worsen their social cohesion. To achieve this goal, the municipalities were classified according to the degree of socioeconomic development, and their accessibility levels were determined before and after the construction of these infrastructures. Firstly, the socioeconomic classification demonstrates that there is predominance in the northern half of the peninsula in the most developed municipalities. Secondly, the accessibility levels show that the same center-peripheral models are going to be kept in the future. Finally, poorly-defined territorial patterns are obtained with respect to the positive or negative effects of new infrastructures on social cohesion. Therefore, it is possible to state that the construction plan is going to partially fulfill its aim, since a quarter of the population is going to be affected by a negative impact on socioeconomic development. As a consequence, people who live here are going to have major problems in achieving social cohesion.

Teammate Prosocial and Antisocial Behaviors Predict Task Cohesion and Burnout: The Mediating Role of Affect.

Science.gov (United States)

Al-Yaaribi, Ali; Kavussanu, Maria

2017-06-01

The manner in which teammates behave toward each other when playing sport could have important achievement-related consequences. However, this issue has received very little research attention. In this study, we investigated whether (a) prosocial and antisocial teammate behaviors predict task cohesion and burnout, and (b) positive and negative affect mediates these relationships. In total, 272 (M age  = 21.86, SD = 4.36) team-sport players completed a multisection questionnaire assessing the aforementioned variables. Structural equation modeling indicated that prosocial teammate behavior positively predicted task cohesion and negatively predicted burnout, and these relationships were mediated by positive affect. The reverse pattern of relationships was observed for antisocial teammate behavior which negatively predicted task cohesion and positively predicted burnout, and these relationships were mediated by negative affect. Our findings underscore the importance of promoting prosocial and reducing antisocial behaviors in sport and highlight the role of affect in explaining the identified relationships.

Unit Cohesion and the Military's "Don't Ask, Don't Tell" Policy

National Research Council Canada - National Science Library

Rea, Theresa

1997-01-01

The Department of Defense policy of excluding known homosexuals from military service is partially based on the assumption that homosexual service members pose a threat to the cohesion of a military unit...

Global sensitivity analysis in the identification of cohesive models using full-field kinematic data

KAUST Repository

Alfano, Marco; Lubineau, Gilles; Paulino, Glá ucio Hermogenes

2015-01-01

Failure of adhesive bonded structures often occurs concurrent with the formation of a non-negligible fracture process zone in front of a macroscopic crack. For this reason, the analysis of damage and fracture is effectively carried out using the cohesive zone model (CZM). The crucial aspect of the CZM approach is the precise determination of the traction-separation relation. Yet it is usually determined empirically, by using calibration procedures combining experimental data, such as load-displacement or crack length data, with finite element simulation of fracture. Thanks to the recent progress in image processing, and the availability of low-cost CCD cameras, it is nowadays relatively easy to access surface displacements across the fracture process zone using for instance Digital Image Correlation (DIC). The rich information provided by correlation techniques prompted the development of versatile inverse parameter identification procedures combining finite element (FE) simulations and full field kinematic data. The focus of the present paper is to assess the effectiveness of these methods in the identification of cohesive zone models. In particular, the analysis is developed in the framework of the variance based global sensitivity analysis. The sensitivity of kinematic data to the sought cohesive properties is explored through the computation of the so-called Sobol sensitivity indexes. The results show that the global sensitivity analysis can help to ascertain the most influential cohesive parameters which need to be incorporated in the identification process. In addition, it is shown that suitable displacement sampling in time and space can lead to optimized measurements for identification purposes.

The preparation, physicochemical properties, and the cohesive energy of liquid sodium containing titanium nanoparticles

International Nuclear Information System (INIS)

Saito, Jun-ichi; Itami, Toshio; Ara, Kuniaki

2012-01-01

Liquid sodium containing titanium nanoparticles (LSnanop) of 10-nm diameter was prepared by dispersing titanium nanoparticles (2 at.% Ti) into liquid sodium with the addition of stirring and ultrasonic sound wave. The titanium nanoparticles themselves were prepared by the vapor deposition method. This new liquid metal, LSnanop, shows a remarkable stability due to the Brownian motion of nanoparticles in liquid sodium medium. In addition, the difference of measured heat of reaction to water between this LSnanop and liquid sodium indicates the existence of cohesive energy between the liquid sodium medium and dispersed titanium nanoparticles. The origin of the cohesive energy, which serves to stabilize this new liquid metal, was explained by the model of screened nanoparticles in liquid sodium. In this model, negatively charged nanoparticles with transferred electrons from liquid sodium are surrounded by the positively charged screening shell, which may inhibit the gathering of nanoparticles by the “Coulombic repulsion coating.” The atomic volume of LSnanop shows the shrinkage from the linear law, which also suggests the existence of cohesive energy. The viscosity of LSnanop is almost the same as that of liquid sodium. This behavior was explained by the Einstein equation. The surface tension of LSnanop is 17 % larger than that of liquid sodium. The cohesive energy and the negative adsorption may be responsible to this increase. Titanium nanoparticles in liquid sodium seem to be free from the Coulomb fission. This new liquid metal containing nanoparticles suggests the possibility to prepare various stable suspensions with new properties.

Global sensitivity analysis in the identification of cohesive models using full-field kinematic data

KAUST Repository

Alfano, Marco

2015-03-01

Failure of adhesive bonded structures often occurs concurrent with the formation of a non-negligible fracture process zone in front of a macroscopic crack. For this reason, the analysis of damage and fracture is effectively carried out using the cohesive zone model (CZM). The crucial aspect of the CZM approach is the precise determination of the traction-separation relation. Yet it is usually determined empirically, by using calibration procedures combining experimental data, such as load-displacement or crack length data, with finite element simulation of fracture. Thanks to the recent progress in image processing, and the availability of low-cost CCD cameras, it is nowadays relatively easy to access surface displacements across the fracture process zone using for instance Digital Image Correlation (DIC). The rich information provided by correlation techniques prompted the development of versatile inverse parameter identification procedures combining finite element (FE) simulations and full field kinematic data. The focus of the present paper is to assess the effectiveness of these methods in the identification of cohesive zone models. In particular, the analysis is developed in the framework of the variance based global sensitivity analysis. The sensitivity of kinematic data to the sought cohesive properties is explored through the computation of the so-called Sobol sensitivity indexes. The results show that the global sensitivity analysis can help to ascertain the most influential cohesive parameters which need to be incorporated in the identification process. In addition, it is shown that suitable displacement sampling in time and space can lead to optimized measurements for identification purposes.

A boundary integral method for a dynamic, transient mode I crack problem with viscoelastic cohesive zone

KAUST Repository

Leise, Tanya L.

2009-08-19

We consider the problem of the dynamic, transient propagation of a semi-infinite, mode I crack in an infinite elastic body with a nonlinear, viscoelastic cohesize zone. Our problem formulation includes boundary conditions that preclude crack face interpenetration, in contrast to the usual mode I boundary conditions that assume all unloaded crack faces are stress-free. The nonlinear viscoelastic cohesive zone behavior is motivated by dynamic fracture in brittle polymers in which crack propagation is preceeded by significant crazing in a thin region surrounding the crack tip. We present a combined analytical/numerical solution method that involves reducing the problem to a Dirichlet-to-Neumann map along the crack face plane, resulting in a differo-integral equation relating the displacement and stress along the crack faces and within the cohesive zone. © 2009 Springer Science+Business Media B.V.

The Dyadic Effects of Family Cohesion and Communication on Health-Related Quality of Life: The Moderating Role of Sex.

Science.gov (United States)

Lim, Jung-Won; Shon, En-Jung

Spouses' ability to care for survivors can be particularly challenging because patients and spouses are interdependent and mutually influence one another. Family functioning such as family cohesion and communication may play a primary role in improving the health-related quality of life (HRQOL) of couples, given that cancer can influence family dynamics. The aims of this study were to investigate the mediating effect of family communication on the relationship between family cohesion and HRQOL and examine the moderating effect of sex on this relationship among cancer survivor-spouse dyads. A total of 91 cancer survivors with a diagnosis of breast, colorectal, or prostate cancer and their spouses were recruited from the University Hospital Registry in Cleveland, Ohio. The dyadic data were analyzed using structural equation modeling with the actor-partner interdependence mediation model. Findings demonstrated that the spouses' own perceived family communication mediated the associations between their own family cohesion and physical HRQOL and between the survivors' family cohesion and physical HRQOL. The spouse actor effects between family communication and HRQOL significantly differed by sex. Enhancing family cohesion and communication within the family can improve the spouses' HRQOL. Findings regarding sex differences serve as a rationale for gender-based approaches to improving HRQOL in survivorship care in the family context. Couple- and/or family-based interventions should be designed to enhance family cohesion and improve family communication skills for effective adjustments within couples and families. Supportive care within the family context can be promoted to address the diverse challenges of survivorship care.

So to Speak: A Computational and Empirical Investigation of Lexical Cohesion of Non-Literal and Literal Expressions in Text

Directory of Open Access Journals (Sweden)

Alexis Palmer

2012-12-01

Full Text Available Lexical cohesion is an important device for signaling text organization. In this paper, we investigate to what extent a particular class of expressions which can have a non-literal interpretation participates in the cohesive structure of a text. Specifically, we look at five expressions headed by a verb which – depending on the context – can have either a literal or a non-literal meaning: bounce off the wall (“to be excited and full of nervous energy”, get one’s feet wet (“to start a new activity or job”, rock the boat (“to disturb the balance or routine of a situation”, break the ice (“to start to get to know people, to overcome initial shyness”, and play with fire (“to take part in a dangerous or risky undertaking”. We look at the problem both from an empirical and a computational perspective. The results from our empirical study suggest that both literal and non-literal expressions exhibit cohesion with their textual context, but that the latter appear to do so to a lesser extent. We also show that an automatically computable semantic relatedness measure based on search engine page counts correlates well with human intuitions about the cohesive structure of a text and can therefore be used to determine the cohesive structure of a text automatically with a reasonable degree of accuracy. This investigation is undertaken from the perspective of computational linguistics. We aim both to model this cohesion computationally and to support our approach to computational modeling with empirical data.

Merotelic kinetochore attachment in oocyte meiosis II causes sister chromatids segregation errors in aged mice.

Science.gov (United States)

Cheng, Jin-Mei; Li, Jian; Tang, Ji-Xin; Hao, Xiao-Xia; Wang, Zhi-Peng; Sun, Tie-Cheng; Wang, Xiu-Xia; Zhang, Yan; Chen, Su-Ren; Liu, Yi-Xun

2017-08-03

Mammalian oocyte chromosomes undergo 2 meiotic divisions to generate haploid gametes. The frequency of chromosome segregation errors during meiosis I increase with age. However, little attention has been paid to the question of how aging affects sister chromatid segregation during oocyte meiosis II. More importantly, how aneuploid metaphase II (MII) oocytes from aged mice evade the spindle assembly checkpoint (SAC) mechanism to complete later meiosis II to form aneuploid embryos remains unknown. Here, we report that MII oocytes from naturally aged mice exhibited substantial errors in chromosome arrangement and configuration compared with young MII oocytes. Interestingly, these errors in aged oocytes had no impact on anaphase II onset and completion as well as 2-cell formation after parthenogenetic activation. Further study found that merotelic kinetochore attachment occurred more frequently and could stabilize the kinetochore-microtubule interaction to ensure SAC inactivation and anaphase II onset in aged MII oocytes. This orientation could persist largely during anaphase II in aged oocytes, leading to severe chromosome lagging and trailing as well as delay of anaphase II completion. Therefore, merotelic kinetochore attachment in oocyte meiosis II exacerbates age-related genetic instability and is a key source of age-dependent embryo aneuploidy and dysplasia.

Evidence that cyclophosphamide can to induce exchanges in the sister chromatids (ICH) through secondary injuries

International Nuclear Information System (INIS)

Morales R, P.; Rodriguez R, R.

1997-01-01

By means of the use of destination protocol of ICH inductive injuries (DLI-ICH), it was studied if interchanges in the sister chromatids (ICH) induced by cyclophosphamide (CP), in the second post-treatment division (ICH-2) are produced by secondary injuries or by fresh injuries. For discard between these possibilities it was administered CP at different periods before of the first post-treatment division, taking as reference the administered time for high dose of bromodeoxyuridine (BrdU ) which was approximately at the beginning of this division. The ICH frequencies that occur in the first, the second and the third synthesis stages (S) were determined. It was observed that when the administered CP was four hours before BrdU , the ICH frequencies of the second and the third S were reduced. The frequency of the first ICH increased lightly in relation to those of the normal protocol (0.5 h before BrdU ) and that the supplying of CP six hours before caused almost a total reduction of ICH of second and third S and an important increment of ICH of first S.This was interpreted as evidence that the ICH-2 are product of secondary injuries. (Author)

Is Territorial Cohesion Necessary for the Sustainable Development of the European Regions?

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RADU C. BARNA

2011-01-01

Full Text Available The Regional policy of the EU is pursuing the harmonious development of the European territory; this is a necessary condition for the creation of an environment that is favourable to the convergence of the Union’s policies. But, for these policies to converge, it is necessary that there are common objectives and these can arise only from the existence of common needs. It is obvious that a very different level of development leads to different needs for people and territories and therefore, to the pursuit of different objectives. The introduction of the territorial cohesion as an objective of the European Union through the Treaty of Lisbon has concluded many years of debate over the essence and future of the EU. But is this a prerequisite for the sustainable development of the EU regions? To answer this question, in this paper we will try to show the importance of the territorial cohesion in the EU. In order to do this, we will place the evolution of this concept in parallel with that of development and also with the process of enlargement and of deepening of the EU. We will thus try to determine the influence that territorial cohesion has on regions and on the European construction so that in the end we should be able to explain the effects that it has on their sustainable development.

Validation of French and German versions of a Perceived Neighborhood Social Cohesion Questionnaire among young Swiss males, and its relationship with substance use.

Science.gov (United States)

Dupuis, Marc; Studer, Joseph; Henchoz, Yves; Deline, Stéphane; Baggio, Stéphanie; N'Goran, Alexandra; Mohler-Kuo, Meichun; Gmel, Gerhard

2016-02-01

This study main purpose was the validation of both French and German versions of a Perceived Neighborhood Social Cohesion Questionnaire. The sample group comprised 5065 Swiss men from the "Cohort Study on Substance Use Risk Factors." Multigroup Confirmatory factor analysis showed that a three-factor model fits the data well, which substantiates the generalizability of Perceived Neighborhood Social Cohesion Questionnaire factor structure, regardless of the language. The Perceived Neighborhood Social Cohesion Questionnaire demonstrated excellent homogeneity (α = 95) and split-half reliability (r = .96). The Perceived Neighborhood Social Cohesion Questionnaire was sensitive to community size and participants' financial situation, confirming that it also measures real social conditions. Finally, weak but frequent correlations between Perceived Neighborhood Social Cohesion Questionnaire and alcohol, cigarette, and cannabis dependence were measured. © The Author(s) 2014.

Erosion of cohesive soil layers above underground conduits

Science.gov (United States)

Luu, Li-Hua; Philippe, Pierre; Noury, Gildas; Perrin, Jérôme; Brivois, Olivier

2017-06-01

Using a recently developed 2D numerical modelling that combines Discrete Element (DEM) and Lattice Boltzmann methods (LBM), we simulate the destabilisation by an hydraulic gradient of a cohesive granular soil clogging the top of an underground conduit. We aim to perform a multi-scale study that relates the grain scale behavior to the macroscopic erosion process. In particular, we study the influence of the flow conditions and the inter-particle contact forces intensity on the erosion kinetic.

Perceived Family Cohesion Moderates Environmental Influences on Prosocial Behavior in Nigerian Adolescent Twins.

Science.gov (United States)

Hur, Yoon-Mi; Taylor, Jeanette; Jeong, Hoe-Uk; Park, Min-Seo; Haberstick, Brett C

2017-06-01

Research shows that perceived family cohesion is positively related to prosocial behavior in adolescents. In this study, we investigated heritability of prosocial behavior (PB) and perceived family cohesion (FC) among Nigerian twins attending public schools in Lagos State, Nigeria (mean age = 14.7 years, SD = 1.7 years), and explored the issue of whether children's perception of cohesive family environment moderated genetic and environmental influences on (PB). The PB scale of the Strengths and Difficulties Questionnaire and the FC scale of the Family Adaptability and Cohesion Evaluation Scale III were completed by 2,376 twins (241 monozygotic (MZ) male, 354 MZ female, 440 dizygotic (DZ) male, 553 DZ female, and 788 opposite-sex DZ twins). A general sex-limitation and the bivariate genotype by environment interaction (G×E) models were applied to the data. The general sex-limitation model showed no significant sex differences, indicating that additive genetic and non-shared environmental influences were, 38% (95% CI = 31, 46) and 62% (95% CI = 54, 69) for PB and 33% (95% CI = 24, 40) and 67% (95% CI = 60, 76) for FC in both sexes. These estimates were similar to those found in Western and Asian twin studies to date. The correlation between PB and FC was 0.36. The best-fitting bivariate G×E model indicated that FC significantly moderated non-shared environmental influence unique to PB (E×E interaction). Specifically, non-shared environmental contributions to PB were highest when FC was lowest, and decreased as the levels of FC increased. However, genetic variances in PB were stable across all levels of FC. These findings suggest that FC reduces individual differences in PB by changing non-shared environmental experiences rather than genetic factors in PB.

Enhanced stimulation of chromosomal translocations and sister chromatid exchanges by either HO-induced double-strand breaks or ionizing radiation in Saccharomyces cerevisiae yku70 mutants

International Nuclear Information System (INIS)

Fasullo, Michael; St Amour, Courtney; Zeng Li

2005-01-01

DNA double-strand break (DSB) repair occurs by homologous recombination (HR) or non-homologous endjoining (NHEJ). In Saccharomyces cerevisiae, expression of both MAT a and MATα inhibits NHEJ and facilitates DSB-initiated HR. We previously observed that DSB-initiated recombination between two his3 fragments, his3-Δ5' and his3-Δ3'::HOcs is enhanced in haploids and diploids expressing both MAT a and MATα genes, regardless of the position or orientation of the his3 fragments. Herein, we measured frequencies of DNA damage-associated translocations and sister chromatid exchanges (SCEs) in yku70 haploid mutants, defective in NHEJ. Translocation and SCE frequencies were measured in strains containing the same his3 fragments after DSBs were made directly at trp1::his3-Δ3'::HOcs. Wild type and yku70 cells were also exposed to ionizing radiation and radiomimetic agents methyl methanesulfonate (MMS), phleomycin, and 4-nitroquinolone-1-oxide (4-NQO). Frequencies of X-ray-associated and DSB-initiated translocations were five-fold higher in yku70 mutants compared to wild type; however, frequencies of phleomycin-associated translocations were lower in the yku70 haploid mutant. Frequencies of DSB-initiated SCEs were 1.8-fold higher in the yku70 mutant, compared to wild type. Thus, DSB-initiated HR between repeated sequences on non-homologous chromosomes and sister chromatids occurs at higher frequencies in yku70 haploid mutants; however, higher frequencies of DNA damage-associated HR in yku70 mutants depend on the DNA damaging agent

Multiple intersecting cohesive discontinuities in 3D reservoir geomechanics

OpenAIRE

Das, K. C.; Sandha, S.S.; Carol, Ignacio; Vargas, P.E.; Gonzalez, Nubia Aurora; Rodrigues, E.; Segura Segarra, José María; Lakshmikantha, Ramasesha Mookanahallipatna; Mello,, U.

2013-01-01

Reservoir Geomechanics is playing an increasingly important role in developing and producing hydrocarbon reserves. One of the main challenges in reservoir modeling is accurate and efficient simulation of arbitrary intersecting faults. In this paper, we propose a new formulation to model multiple intersecting cohesive discontinuities (faults) in reservoirs using the XFEM framework. This formulation involves construction of enrichment functions and computation of stiffness sub-matrices for bulk...

Family Rituals and Quality of Life in Children With Cancer and Their Parents: The Role of Family Cohesion and Hope.

Science.gov (United States)

Santos, Susana; Crespo, Carla; Canavarro, M Cristina; Kazak, Anne E

2015-08-01

Family rituals are associated with adaptive functioning in pediatric illness, including quality of life (QoL). This article explores the role of family cohesion and hope as mediators of this association in children with cancer and their parents. Portuguese children with cancer (N = 389), on- and off-treatment, and one of their parents completed self-report measures. Structural equation modeling was used to examine direct and indirect links between family rituals and QoL. When children and parents reported higher levels of family rituals, they also reported more family cohesion and hope, which were linked to better QoL. At the dyadic level, children's QoL was related to parents' family rituals through the child's family cohesion. This model was valid across child's age-group, treatment status, and socioeconomic status. Family rituals are important in promoting QoL in pediatric cancer via family cohesion and hope individually and via family cohesion in terms of parent-child interactions. © The Author 2015. Published by Oxford University Press on behalf of the Society of Pediatric Psychology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Family cohesion and the loneliness of adolescents from temporarily disconnected families due to economic migration

Directory of Open Access Journals (Sweden)

Dołęga Zofia

2015-03-01

Full Text Available The paper reports the results of a comparative analysis of the two groups students coming from temporarily disconnected families due to foreign work parents (TDF, n = 68; male = 30, female = 38 and teenagers with the same social environment (NDF, n = 179, male = 89, female = 90, but without the experience of separation time (N= 247. The subject of the analysis was: the cohesion of a family from the perspective of the evaluated adolescent and three factors of psychological loneliness: social loneliness (sense of social marginalization and isolation, emotional loneliness (solitude and existential loneliness (sense of self-alienation. The Loneliness Scale (SBS was used based on an original concept of multidimensional sense of loneliness. The questionnaire for the survey of family cohesion (KSR were used too. The age (12-14 and 15-17, gender, family structure and the family lifestyle were controlled. Obtained results revealed significantly lower cohesion and significantly higher existential loneliness in group of teenagers from temporarily disconnected families (TDF. Not confirmed the supposition that made in earlier studies of temporarily disconnected families due to economic migration, that these teenagers suffer from a sense of emotional loneliness There has also confirmed the belief that the level of family cohesion and a sense of loneliness in adolescents is associated with atypical organization of family life associated with the duration of migration of parent/parents, frequency of contact with family members working abroad: mothers, fathers or broth parents, the duration of stays at home

Time dependent fracture and cohesive zones

Science.gov (United States)

Knauss, W. G.

1993-01-01

This presentation is concerned with the fracture response of materials which develop cohesive or bridging zones at crack tips. Of special interest are concerns regarding crack stability as a function of the law which governs the interrelation between the displacement(s) or strain across these zones and the corresponding holding tractions. It is found that for some materials unstable crack growth can occur, even before the crack tip has experienced a critical COD or strain across the crack, while for others a critical COD will guarantee the onset of fracture. Also shown are results for a rate dependent nonlinear material model for the region inside of a craze for exploring time dependent crack propagation of rate sensitive materials.

Methicillin-Resistant Staphylococcus aureus Biofilms and Their Influence on Bacterial Adhesion and Cohesion

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Khulood Hamid Dakheel

2016-01-01

Full Text Available Twenty-five methicillin-resistant Staphylococcus aureus (MRSA isolates were characterized by staphylococcal protein A gene typing and the ability to form biofilms. The presence of exopolysaccharides, proteins, and extracellular DNA and RNA in biofilms was assessed by a dispersal assay. In addition, cell adhesion to surfaces and cell cohesion were evaluated using the packed-bead method and mechanical disruption, respectively. The predominant genotype was spa type t127 (22 out of 25 isolates; the majority of isolates were categorized as moderate biofilm producers. Twelve isolates displayed PIA-independent biofilm formation, while the remaining 13 isolates were PIA-dependent. Both groups showed strong dispersal in response to RNase and DNase digestion followed by proteinase K treatment. PIA-dependent biofilms showed variable dispersal after sodium metaperiodate treatment, whereas PIA-independent biofilms showed enhanced biofilm formation. There was no correlation between the extent of biofilm formation or biofilm components and the adhesion or cohesion abilities of the bacteria, but the efficiency of adherence to glass beads increased after biofilm depletion. In conclusion, nucleic acids and proteins formed the main components of the MRSA clone t127 biofilm matrix, and there seems to be an association between adhesion and cohesion in the biofilms tested.

Liquid distribution and cohesion in wet granular assemblies beyond the capillary bridge regime

International Nuclear Information System (INIS)

Scheel, M; Seemann, R; Brinkmann, M; Herminghaus, S; Di Michiel, M; Sheppard, A

2008-01-01

Dry sand turns into a stiff and moldable material as soon as it is mixed with some liquid. This is a direct consequence of the internal liquid-air interfaces spanning between the grains which causes capillary cohesion by virtue of the surface tension of the liquid. As a model for wet granulates we investigated random packings of submillimeter spherical beads mixed with water. Measurements of the tensile strength and the fluidization threshold demonstrate that the mechanical stiffness is rather insensitive to the liquid content over a wide range. Only for a high liquid content, when more than half of the available pore space is filled with liquid, does the capillary cohesion weaken. In order to understand the interplay between the mechanical properties and the liquid content, we investigated the liquid distribution in random packings of glass spheres by means of x-ray microtomography. The three-dimensional images reveal that the liquid forms a network of capillary bridges fused at local triangular bead configurations. The spontaneous organization of the liquid into these ramified structures, which exhibit a large liquid-air interface, is responsible for the constancy of the cohesive forces in a wide range of liquid contents beyond the onset of capillary bridge coalescence.

Is social cohesion relevant to a city in the global South?

International Development Research Centre (IDRC) Digital Library (Canada)

This article investigates the relevance of international framings of social cohesion and collective efficacy, which have largely ... an ethnographic study conducted in Khayelitsha township in the Western Cape, where a major internationally funded and conceptualised ... the global South? A case study of Khayelitsha township ...

Formation of a cohesive floodplain in a dynamic experimental meandering river

NARCIS (Netherlands)

Dijk, W.M. van; Lageweg, W.I. van de; Kleinhans, M.G.

2013-01-01

Field studies suggest that a cohesive floodplain is a necessary condition for meandering in contrast to braided rivers. However, it is only partly understood how the balance between floodplain construction by overbank deposition and removal by bank erosion and chutes leads to meandering. This is

Responses to Forces Influencing Cohesion as a Function of Player Status and Level of Male Varsity Basketball Competition.

Science.gov (United States)

Gruber, Joseph J.; Gray, Gary R.

1982-01-01

A study analyzed team cohesion perceptions of 515 male varsity basketball players (10 to 22 years of age) to determine if factors influencing team cohesion were a function of competitive intensity or of the importance of individual players to their team. Players with the most game playing time were more satisfied than those with less playing time.…

Discrimination and adjustment among Chinese American adolescents: family conflict and family cohesion as vulnerability and protective factors.

Science.gov (United States)

Juang, Linda P; Alvarez, Alvin A

2010-12-01

We examined racial/ethnic discrimination experiences of Chinese American adolescents to determine how discrimination is linked to poor adjustment (i.e., loneliness, anxiety, and somatization) and how the context of the family can buffer or exacerbate these links. We collected survey data from 181 Chinese American adolescents and their parents in Northern California. We conducted hierarchical regression analyses to examine main effects and 2-way interactions of perceived discrimination with family conflict and family cohesion. Discrimination was related to poorer adjustment in terms of loneliness, anxiety, and somatization, but family conflict and cohesion modified these relations. Greater family conflict exacerbated the negative effects of discrimination, and greater family cohesion buffered the negative effects of discrimination. Our findings highlight the importance of identifying family-level moderators to help adolescents and their families handle experiences of discrimination.

Cohesion assessment of student groups from the faculty of dentistry at Burdenko Voronezh State Medical University

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Pashkov A. N.

2017-10-01

Full Text Available the article presents data on the study of the cohesion of 115 students from the faculty of dentistry at Burdenko Voronezh State Medical University. The study revealed that students have high and medium favorable psychological climate. 99 of them have the average level of group cohesion, and 16 revealed a low level of this indicator. To improve the educational process and interpersonal relations, these results must be taken into account when forming groups.

Disaggregation of small, cohesive rubble pile asteroids due to YORP

Science.gov (United States)

Scheeres, D. J.

2018-04-01

The implication of small amounts of cohesion within relatively small rubble pile asteroids is investigated with regard to their evolution under the persistent presence of the YORP effect. We find that below a characteristic size, which is a function of cohesive strength, density and other properties, rubble pile asteroids can enter a "disaggregation phase" in which they are subject to repeated fissions after which the formation of a stabilizing binary system is not possible. Once this threshold is passed rubble pile asteroids may be disaggregated into their constituent components within a finite time span. These constituent components will have their own spin limits - albeit potentially at a much higher spin rate due to the greater strength of a monolithic body. The implications of this prediction are discussed and include modification of size distributions, prevalence of monolithic bodies among meteoroids and the lifetime of small rubble pile bodies in the solar system. The theory is then used to place constraints on the strength of binary asteroids characterized as a function of their type.

Modelling the double cantilever beam test with bending moments by using bilinear discontinuous cohesive laws

DEFF Research Database (Denmark)

Valvo, Paolo S.; Sørensen, Bent F.; Toftegaard, Helmuth Langmaack

2015-01-01

A theoretical model of the double cantilever beam tests with bending moments (DCB-UBM) is presented. The specimen is modelled as the assemblage of two laminated beams connected by a cohesive interface. It is assumed that the traction-separation laws – i.e. the relationships between the interfacial...... the cohesive law parameters from experiments. Experimental tests have been conducted on glass fibre reinforced specimens under pure mode I and II loading conditions. The predictions of the theoretical model turn out to be in very good agreement with the experimental results....

Texture, Textuality and Political Discourse: A Study of Lexical Cohesion in Nigeria's President Goodluck Jonathan's Inaugural Address, May, 2011

Science.gov (United States)

Enyi, Amaechi Uneke; Chitulu, Mark Ononiwu

2015-01-01

This study, entitled, "Texture and textuality in Political Discourse: A Study of Cohesive Devices in President Goodluck Jonathan's Inaugural Address-May, 2011" was an analysis of the lexical cohesive devices employed by Nigeria's President Goodluck Jonathan in crafting his May, 2011's Presidential Inaugural Address (PIA). Guided by the…

Sister chromatid exchanges in X-ray irradiated blood lymphocytes from patients with hereditary diseases with radioresistant DNA synthesis

International Nuclear Information System (INIS)

Pleskach, N.M.; Andriadze, M.I.; Mikhel'son, V.M.; Zhestyanikov, V.D.

1988-01-01

X-ray irradiation induced sister chromatid exchanges (SCE) in blood lymphocytes from patient with Down's syndrome and adult progeria (in both the cases radioresistant DNA synthesis takes place). In normal lymphocytes (in which ionizing radiation inhibits the replicative synthesis of DNA) the rate of SCE rises with the rise of radiation dose. Thus, the rate of SCE in X-ray irradiated lymphocytes is in reverse dependence with radioresistance of replicative synthesis of DNA. The data obtained are explained in accordance with the replicative hypothesis of the SCE nature (Painter, 1980a): in cells of patients with Down's syndrome, xeroderma pigmentosum from 2 and progeria of adults the time of existence of partly replicated clusters of replicons is decreased due to radioresistant replicative synthesis of DNA, but the presence of partly replicated clusters of replicons in necessary for SCE formation. Therefore the rate of SCF in X-irradiated cells of these patients decreases

Erosion of cohesive soil layers above underground conduits

Directory of Open Access Journals (Sweden)

Luu Li-Hua

2017-01-01

Full Text Available Using a recently developed 2D numerical modelling that combines Discrete Element (DEM and Lattice Boltzmann methods (LBM, we simulate the destabilisation by an hydraulic gradient of a cohesive granular soil clogging the top of an underground conduit. We aim to perform a multi-scale study that relates the grain scale behavior to the macroscopic erosion process. In particular, we study the influence of the flow conditions and the inter-particle contact forces intensity on the erosion kinetic.

Relationships of family conflict, cohesion, and chaos in the home environment on maternal and child food-related behaviours.

Science.gov (United States)

Martin-Biggers, Jennifer; Quick, Virginia; Zhang, Man; Jin, Yanhong; Byrd-Bredbenner, Carol

2018-04-01

This study examined how food-related behaviours differed in mothers and their preschool children by levels of family functioning (cohesion and conflict) and household disorganization (chaos). A nationally representative sample of mothers of preschoolers completed an online survey assessing food-related behaviours of themselves and their children. Maternal and child diet, eating behaviours, and health status; household availability of fruits/vegetables, salty/fatty snacks, and sugar-sweetened beverages; family mealtime atmosphere; and family conflict, cohesion, and household chaos were assessed with valid, reliable scales. Cluster analyses assigned families into low, middle, and high conflict, cohesion, and chaos groups. Participants (n = 550) were 72% White, and 82% had some post-secondary education. Regression analysis examining the association of cluster grouping levels on diet-related behaviour measures revealed that positive home environments (i.e., low family conflict, high family cohesion, and low household chaos) were associated with healthier food-related behaviours (e.g., increased fruits/vegetables intake), whereas negative home environments (i.e., high family conflict, low family cohesion, and high household chaos) were associated with unhealthy food-related behaviours (e.g., greater % total calories from fat) even after controlling for sociodemographic and related behavioural factors. Findings suggest family functioning and household chaos are associated with food-related behaviours. This frequently overlooked component of family interaction may affect intervention outcomes and objectives of educational and interventional initiatives. © 2017 John Wiley & Sons Ltd.

Relationships between cohesion, collective efficacy and performance in professional basketball teams: an examination of mediating effects.

Science.gov (United States)

Heuzé, Jean-Philippe; Raimbault, Nicolas; Fontayne, Paul

2006-01-01

The main aim of this study was to examine mediating effects in the relationships between cohesion, collective efficacy and performance in professional basketball teams. A secondary aim was to examine the correlates of collective efficacy in a professional sport. A total of 154 French and foreign professional players completed French or English versions of questionnaires about cohesion and collective efficacy. Two composite measures of individual performance were used (pre- and post-performance). Individual-level analyses were performed. Regression analyses supported two mediating relationships with collective efficacy as a mediator of the pre-performance - Group integration-task relationship, and Group integration-task as a mediator of the pre-performance - collective efficacy relationship. Statistical analyses indicated that neither Group integration-task nor collective efficacy was a better mediator in the relationship between pre-performance and the other group variables. Results also revealed positive relationships between three dimensions of cohesion (i.e. Individual attractions to the group-task, Group integration-task, Group integration-social) and collective efficacy. These findings suggest that in professional basketball teams, staff members should look after athletes who perform at a lower or below their usual level because their performances might lead them into a downward cohesion - collective efficacy spiral. Staff members should also develop a high quality of group functioning, both on and off the basketball court, given its relationship with collective efficacy.

A comparative investigation of DNA strand breaks, sister chromatid exchanges and K-ras gene mutations induced by cadmium salts in cultured human cells

International Nuclear Information System (INIS)

Mouron, Silvana Andrea; Grillo, Claudia Alejandra; Dulout, Fernando Noel; Golijow, Carlos Daniel

2004-01-01

Cadmium (Cd) is a toxic heavy metal of continuing occupational and environmental concern with a wide variety of adverse effects. Several studies have shown that cadmium produces DNA strand breaks, DNA-protein cross-links, oxidative DNA damage, chromosomal aberrations, dysregulation of gene expression resulting in enhanced proliferation, depressed apoptosis and/or altered DNA repair. This study was undertaken to investigate the ability of cadmium chloride (CdCl 2 ) and cadmium sulphate (CdSO 4 ) to induce point mutations in codon 12 of the K-ras protooncogene assessed by polymerase chain reaction-single strand conformation polymorphisms (PCR-SSCP) and RFLP-enriched PCR methods. Also their genotoxic effects were analyzed by the comet assay and sister chromatid exchanges test. The human lung fibroblast cell line MRC-5 was used for the experiments. Sister chromatid exchanges assay (SCEs) frequencies were significantly increased in cells exposed to cadmium salts in relation to controls (p < 0.001). Despite the slow increment observed in the three comet parameters considered when cells were treated with cadmium chloride, significant differences between groups were only found in the variable comet moment (CM) (p < 0.005). On the other hand, when cells were exposed to cadmium sulphate, the Kruskal-Wallis test showed highly significant differences between groups for migration, tail moment and comet moment parameters (p < 0.001). Nevertheless, a null or weak point mutation induction in K-ras protooncogene was detected using polymerase chain reaction-low ionic strength-single strand conformation polymorphisms (PCR-LIS-SSCP) and RFLP-enriched PCR methods when cells were treated with cadmium salts. Thus, inorganic cadmium produces genotoxicity in human lung fibroblast MRC-5 cells, in the absence of significant point mutation of the K-ras gene

[Adaptation of the MSCI for the measurement of cohesion in Spanish young soccer players].

Science.gov (United States)

García Quinteiro, Eva María; Rodríguez Casal, Mauro; Andrade, Elena M; Arce, Constantino

2006-08-01

This work describes the Spanish adaptation and studies the psychometric properties of Yukelson, Weinberg, and Jackson's Multidimensional Sport Cohesion Instrument (MSCI) with a sample of 173 soccer players. The Spanish version is composed of 22 items grouped in four factors: quality of teamwork (performance aspects), attraction to the group, valued roles and quality of teamwork (interpersonal relationships), that accounted for 53.30% of the total variance. Reliability coefficients (Cronbach's Alphas) for the factors ranged from .84 (factor 1) to .56 (factor 4). Suggestions are made for future research on the validity of the scale, mainly in terms of convergence with other multidimensional measures of sport cohesion.

[A measure of team cohesion in sport. Spanish adaptation of Group Environment Questionnaire (GEQ)].

Science.gov (United States)

Iturbide, Luis María; Elosua, Paula; Yanes, Félix

2010-08-01

The aim of this work was to adapt the Group Environment Questionnaire (GEQ) to Spanish. Judgmental procedures were used to assess the linguistic and cultural equivalence of the versions. Psychometric procedures were used in the operational phase of the study. The normative sample comprised 924 sportsmen/sportswomen from 75 teams. The GEQ scale showed suitable indexes of internal consistency and a bidimensional structure based on two factors of the cohesion model, the Task component and the Social component. In addition, a positive relation between team-performance and the Task component of team cohesion was observed. Overall, the results supported the Spanish version of the GEQ.

Simulating Dynamic Fracture in Oxide Fuel Pellets Using Cohesive Zone Models

Energy Technology Data Exchange (ETDEWEB)

R. L. Williamson

2009-08-01

It is well known that oxide fuels crack during the first rise to power, with continued fracture occurring during steady operation and especially during power ramps or accidental transients. Fractures have a very strong influence on the stress state in the fuel which, in turn, drives critical phenomena such as fission gas release, fuel creep, and eventual fuel/clad mechanical interaction. Recently, interest has been expressed in discrete fracture methods, such as the cohesive zone approach. Such models are attractive from a mechanistic and physical standpoint, since they reflect the localized nature of cracking. The precise locations where fractures initiate, as well as the crack evolution characteristics, are determined as part of the solution. This paper explores the use of finite element cohesive zone concepts to predict dynamic crack behavior in oxide fuel pellets during power-up, steady operation, and power ramping. The aim of this work is first to provide an assessment of cohesive zone models for application to fuel cracking and explore important numerical issues associated with this fracture approach. A further objective is to provide basic insight into where and when cracks form, how they interact, and how cracking effects the stress field in a fuel pellet. The ABAQUS commercial finite element code, which includes powerful cohesive zone capabilities, was used for this study. Fully-coupled thermo-mechanical behavior is employed, including the effects of thermal expansion, swelling due to solid and gaseous fission products, and thermal creep. Crack initiation is determined by a temperature-dependent maximum stress criterion, based on measured fracture strengths for UO2. Damage evolution is governed by a traction-separation relation, calibrated to data from temperature and burn-up dependent fracture toughness measurements. Numerical models are first developed in 2D based on both axisymmetric (to explore axial cracking) and plane strain (to explore radial

Effects of spatial variation in cohesion over the concrete-rock interface on dam sliding stability

Directory of Open Access Journals (Sweden)

Alexandra Krounis

2015-12-01

Full Text Available The limit equilibrium method (LEM is widely used for sliding stability evaluation of concrete gravity dams. Failure is then commonly assumed to occur along the entire sliding surface simultaneously. However, the brittle behaviour of bonded concrete-rock contacts, in combination with the varying stress over the interface, implies that the failure of bonded dam-foundation interfaces occurs progressively. In addition, the spatial variation in cohesion may introduce weak spots where failure can be initiated. Nonetheless, the combined effect of brittle failure and spatial variation in cohesion on the overall shear strength of the interface has not been studied previously. In this paper, numerical analyses are used to investigate the effect of brittle failure in combination with spatial variation in cohesion that is taken into account by random fields with different correlation lengths. The study concludes that a possible existence of weak spots along the interface has to be considered since it significantly reduces the overall shear strength of the interface, and implications for doing so are discussed.

Numerical simulation of fatigue crack growth rate and crack retardation due to an overload using a cohesive zone model

NARCIS (Netherlands)

Silitonga, S.; Maljaars, J.; Soetens, F.; Snijder, H.H.

2014-01-01

In this work, a numerical method is pursued based on a cohesive zone model (CZM). The method is aimed at simulating fatigue crack growth as well as crack growth retardation due to an overload. In this cohesive zone model, the degradation of the material strength is represented by a variation of the

Aspects of cohesion, tense and pronoun usage in the discourse of the older language-impaired child

Directory of Open Access Journals (Sweden)

Hilary Berger

1978-11-01

Full Text Available Aspects of the discourse of 5 language-impaired children and 5 children with no language impairment, aged approximately 9 years, were compared. A film and a story sequence were utilised to elicit narratives on which, measures of cohesion, tense and pronouns were appraised. Measures of cohesion refer  to the ability to indicate appropriately the relations of meaning with regard to situational context. Measures of tense include aspects of tense range and tense continuity. Measures of  pronouns refer  to the anaphoric use of  pronouns with non-ambiguous referents.  The group of language-impaired children was found  to be significantly poorer on measures of  cohesion and pronominal usage than the normal children, whereas a significant difference between the two groups was not revealed on measures of tense. Possible factors  accounting for  these findings  were discussed and implications for the diagnosis and therapy of the older language-impaired child were considered.

[Optimism, family cohesion and treatment as predictors of quality of life in blood cancer diseases].

Science.gov (United States)

Lavielle-Sotomayor, Pilar; Rozen-Fuller, Etta; Bustamante-Rojano, Juan; Martínez-Murillo, Carlos

2017-01-01

Quality of life must be a part of the goals of care given to blood cancer patients and it must be used to assess the effectiveness of their treatment. The objective was to evaluate the quality of life of patients with leukemia and its relationship with psychological, familial and disease-related aspects. An analytic cross-sectional study was carried out in patients with acute leukemia at different stages of treatment. We used SF-36, Optimism and Family Cohesion scales. Quality of life was affected physically and mentally in the treatment phases aimed to mitigate the active, and the advanced stage of this disease (50.6 ± 25.6, 62 ± 14.3; 46 ± 23.2, 53.8 ± 23.4, respectively), regardless of gender, age, level of optimism and family cohesion. Patients could carry out basic functions of self-care (bathing, feeding, etcetera), but not activities of daily living (shopping, household chores, etcetera), which require a greater effort. Although the patients perceived having been affected in the emotional health area-by the presence of anxiety and depression-they did not consider that these alterations limited their ability to carry out work and everyday activities. Quality of life was most affected at mental dimension and physical dimension, mainly in patients at induction and palliative treatment. The results showed that the objectives of care aimed to reduce symptoms and maintain patient comfort are not achieved.

Questioning territorial cohesion: (Un)equal access to services of general interest

Czech Academy of Sciences Publication Activity Database

Malý, Jiří

-, August 2016 (2016), s. 1-21 ISSN 1056-8190 Institutional support: RVO:68145535 Keywords : territorial cohesion * services of general interest * accessibility * spatial justice * Czech Republic Subject RIV: DE - Earth Magnetism, Geodesy, Geography Impact factor: 1.272, year: 2016 http://onlinelibrary.wiley.com/doi/10.1111/pirs.12250/full

Too Many Friends: Social Integration, Network Cohesion and Adolescent Depressive Symptoms

Science.gov (United States)

Falci, Christina; McNeely, Clea

2009-01-01

Using a nationally representative sample of adolescents, we examine associations among social integration (network size), network cohesion (alter-density), perceptions of social relationships (e.g., social support) and adolescent depressive symptoms. We find that adolescents with either too large or too small a network have higher levels of…

Emotional Intelligence, Communication Competence, and Student Perceptions of Team Social Cohesion

Science.gov (United States)

Troth, Ashlea C.; Jordan, Peter J.; Lawrence, Sandra A.

2012-01-01

Students generally report poor experiences of group work in university settings. This study examines whether individual student perceptions of team social cohesion are determined by their level of emotional intelligence (EI) and whether this relationship is mediated by their communication skills. Business students (N = 273) completed the 16-item…