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Sample records for chris tanner leigh

  1. Adult onset Leigh syndrome

    Directory of Open Access Journals (Sweden)

    Pandit Lekha

    2007-01-01

    Full Text Available Leigh syndrome is a rare progressive mitochondrial disorder of oxidative metabolism. Though it has been reported in infancy and childhood, it is rarely described in adults. The authors describe a patient who had clinical and magnetic resonance imaging features diagnostic of Leigh syndrome, with supportive biochemical and muscle histochemistry evidence.

  2. Tony Tanner. The American Mystery.

    Directory of Open Access Journals (Sweden)

    Marc Chénetier

    2006-04-01

    Full Text Available Tony Tanner nous a quittés. Tony Tanner ne nous a pas quittés. Tony Tanner ne peut pas nous quitter. Parce qu’il est depuis peu décédé. Parce qu’il nous offre ces pages aujourd’hui. Parce qu’il faudra toujours se nourrir de ses grands livres et mesurer à leur aune propos et jugements sur la littérature américaine. 
Sans lui, naguère, qui eût osé s’aventurer dans les terres inexplorées de la fiction récente ? Pourtant, dans son splendide isolement, ce courageux maverick n’a jamais cédé à la te...

  3. On Decoding Irregular Tanner Codes

    CERN Document Server

    Even, Guy

    2011-01-01

    We present a new combinatorial characterization for local-optimality of a codeword in irregular Tanner codes. This characterization is a generalization of [Arora, Daskalakis, Steurer; 2009] and [Vontobel; 2010]. The main novelty in this characterization is that it is based on a conical combination of subtrees in the computation trees. These subtrees may have any degree in the local-code nodes and may have any height (even greater than the girth). We prove that local-optimality in this new characterization implies Maximum-Likelihood (ML) optimality and LP-optimality. We also show that it is possible to compute efficiently a certificate for the local-optimality of a codeword given the channel output. We apply this characterization to regular Tanner codes. We prove a lower bound on the noise threshold in channels such as BSC and AWGNC. When the noise is below this lower bound, the probability that LP decoding fails diminishes doubly exponentially in the girth of the Tanner graph. We use local optimality also to ...

  4. The "double panda" sign in Leigh disease.

    Science.gov (United States)

    Sonam, Kothari; Bindu, P S; Gayathri, Narayanappa; Khan, Nahid Akhtar; Govindaraju, C; Arvinda, Hanumanthapura R; Nagappa, Madhu; Sinha, Sanjib; Thangaraj, K; Taly, Arun B

    2014-07-01

    Although the "face of the giant panda" sign on magnetic resonance imaging (MRI) is traditionally considered to be characteristic of Wilson disease, it has also been reported in other metabolic disorders. This study describes the characteristic "giant panda" sign on MRI in a child with Leigh disease. The diagnosis was based on the history of neurological regression; examination findings of oculomotor abnormalities, hypotonia, and dystonia; raised serum lactate levels; and characteristic brain stem and basal ganglia signal changes on MRI. The midbrain and pontine tegmental signal changes were consistent with the "face of the giant panda and her cub" sign. In addition to Wilson disease, metabolic disorders such as Leigh disease should also be considered in the differential diagnosis of this rare imaging finding.

  5. Leigh syndrome: Clinical and paraclinical study

    Directory of Open Access Journals (Sweden)

    "Ashrafi MR

    2002-08-01

    Full Text Available During two years study about mitochondrial disease (Sep 1999-Agu 2001, 15 cases of Leigh syndrome (LS were diagnosed, that consisted of 11 boys and 4 girls aged between 6 to 156 (mean: 40.5 months. Most of the patients (46.7% became symptomatic between 1-5 years of age. Triggering factors were reported in 66.6% of the patients and 40% of them became symptomatic after infections. The most frequent presenting symptoms of the patients were somnolence and lethargy (40%, developmental regression (20% and seizure (13.3%. The most common neurologic findings were developmental regression or arrest (93.3%, seizure (93.3% abnormal tone (86.7% and abnormal movements (53.3%. Blood lactate increased in 93.3% and blood ammonia elevated in 26.7% of the cases. Symmetric striatal necrosis (100% and caudate nucleus involvement (73.3% were the most frequent neuroimaging findings of the patients.

  6. Post-Tanner spreading of nematic droplets

    Energy Technology Data Exchange (ETDEWEB)

    Mechkov, S; Oshanin, G [Laboratoire de Physique Theorique de la Matiere Condensee, Universite Pierre et Marie Curie, 4 place Jussieu, 75252 Paris Cedex 5 (France); Cazabat, A M, E-mail: mechkov@lptmc.jussieu.f, E-mail: anne-marie.cazabat@lps.ens.f, E-mail: oshanin@lptmc.jussieu.f [Laboratoire de Physique Statistique, Ecole Normale Superieure, 75252 Paris Cedex 5 (France)

    2009-11-18

    The quasistationary spreading of a circular liquid drop on a solid substrate typically obeys the so-called Tanner law, with the instantaneous base radius R(t) growing with time as Rapproxt{sup 1/10}-an effect of the dominant role of capillary forces for a small-sized droplet. However, for droplets of nematic liquid crystals, a faster spreading law sets in at long times, so that Rapproxt{sup a}lpha with alpha significantly larger than the Tanner exponent 1/10. In the framework of the thin film model (or lubrication approximation), we describe this 'acceleration' as a transition to a qualitatively different spreading regime driven by a strong substrate-liquid interaction specific to nematics (antagonistic anchoring at the interfaces). The numerical solution of the thin film equation agrees well with the available experimental data for nematics, even though the non-Newtonian rheology has yet to be taken into account. Thus we complement the theory of spreading with a post-Tanner stage, noting that the spreading process can be expected to cross over from the usual capillarity-dominated stage to a regime where the whole reservoir becomes a diffusive film in the sense of Derjaguin.

  7. Crossing Chris: Some Markerian Affinities

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    Adrian Martin

    2010-01-01

    -pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

    Abstract (E: This essay creatively explores a group of artists, writers, and other special individuals whose work or life story can be described as having an intriguing affinity with the protean career of Chris Marker. Avoiding the ‘usual suspects’ (such as Godard or Sebald, it discusses gossip columnist Milt Machlin, record collector Harry Smith, painter Gianfranco Baruchello, writer-filmmaker Edgardo Cozarinsky, and several others. From this constellation, a particular view of Markerian poetics emerges, touching upon the meanings of anonymity, storytelling, history and archiving.

     

    Abstract (F: Cet essai brosse de manière créative le portrait d’un groupe d'artistes, d'écrivains et d'autres personnes particulières dont le travail ou la biographie peuvent être décrits comme montrant une étrange mais certaine connivence avec la carrière protéiforme de Chris Marker. Evitant les lieux communs (comme Godard ou Sebald, cet article trace des références moins attendues :

  8. OBITUARY Chris Beling, 1955-2010

    Science.gov (United States)

    Coleman, P. G.

    2011-01-01

    This short tribute to Chris Beling, who died in July 2010 at the age of 54, is written on behalf of all members of the positron research community, by whom he was much loved and admired. Obituary Picture 1 Chris Beling, a much respected and admired member of the positron research community who was a familiar face at SLOPOS and other positron conferences over the past three decades, suffered heart failure as he swam out to rescue his younger brother Jeremy while holidaying in his home town of Paignton, in the southwest of England, on June 18 2010. Chris gained a first-class honours degree in physics at Keble College, Oxford, in 1977, and his PhD in Radiation Physics from the University of London in 1981. His postdoctoral research, performed with Alan Smith at St Bart's Medical College in London, focussed on positron studies of liquids [1]. His appointment as a lecturer at University College London in 1983 marked the beginning of his research involving positron beams [2] which was to continue for the rest of his life. In 1987 he moved to the University of Hong Kong (HKU), where he became professor of physics in 2007, working with Professor Steve Fung (with whom he studied at Oxford) and later with Francis Ling. During his 23 years in Hong Kong Chris developed his research interests, concentrating principally on positron beam studies of semiconductors [3]. His brother Jeremy commented that 'moving to Hong Kong was the making of Chris; he found love and happiness'. Chris's research interests reflected the deep intellectual interest he had in his work. He maintained a strong interest in developing the capabilities of positron beam systems - initially by proposing models for field-assisted moderators to increase slow positron yields [4] and later by constructing a hybrid magnetic/electrostatic beam [5] and scanning annihilation spectroscopy [6], among other imaginative advances. His interests in semiconductor physics led him to develop a positron technique analogous to

  9. 76 FR 48898 - Robert Leigh Kale, M.D., Decision and Order

    Science.gov (United States)

    2011-08-09

    ... Enforcement Administration Robert Leigh Kale, M.D., Decision and Order On September 9, 2010, the Deputy... Show Cause to Robert Leigh Kale, M.D. (Registrant), of Fort Smith, Arkansas. ] The Show Cause Order....100(b) and 0.104, I order that DEA Certificate of Registration, BK9514375, issued to Robert Leigh...

  10. A rare mitochondrial disorder: Leigh sydrome - a case report

    Directory of Open Access Journals (Sweden)

    Shrikhande Dhananjay Y

    2010-09-01

    Full Text Available Abstract Leigh syndrome is a rare progressive neurodegenerative, mitochondrial disorder of childhood with only a few cases documented from India. The clinical presentation of Leigh syndrome is highly variable. However, in most cases it presents as a progressive neurological disease with motor and intellectual developmental delay and signs and symptoms of brain stem and/or basal ganglia involvement. Raised lactate levels in blood and/or cerebrospinal fluid is noted. It is the neuroimaging, mainly the Magnetic Resonance Imaging showing characteristic symmetrical necrotic lesions in the basal ganglia and/or brain stem that leads to the diagnosis. Here, we report a case of 7 months old female child presenting to us with status epilepticus, delayed developmental milestones and regression of the achieved milestones suspected to be a case of neurodegenerative disorder, which on MRI was diagnosed as Leigh syndrome.

  11. Anesthetic considerations in Leigh disease: Case report and literature review

    Directory of Open Access Journals (Sweden)

    Abdullah Sulieman Terkawi

    2012-01-01

    Full Text Available Leigh disease is an extremely rare disorder, characterized by a progressive neurodegenerative course, with subacute necrotizing encephalomyelopathy. It usually presents in infancy with developmental delay, seizures, dysarthria, and ataxia. These patients may also develop episodes of lactic acidosis that usually lead to respiratory failure and death. Due to the rarity of the condition, the most appropriate anesthetic plan remains unclear. We present a patient with Leigh disease, who required general anesthesia. The pathogenesis of the disease is discussed and previous reports of perioperative care from the literature are reviewed.

  12. Chris Patten: peame Venemaa suhtes silmad lahti hoidma / Chris Patten ; interv. Kadri Liik

    Index Scriptorium Estoniae

    Patten, Chris

    2005-01-01

    Oxfordi ja Newcastle'i ülikooli kantsler, Euroopa Komisjoni endine välisvolinik vastab küsimustele, mis puudutavad uute Euroopa Liidu liikmesriikide toimetulekut ühenduses, ühenduse välispoliitikat ja suhteid Venemaaga ning Eesti-Vene piirilepingut. Lisa: Chris Patten

  13. The human biology of Jim Tanner.

    Science.gov (United States)

    Cameron, Noël

    2012-09-01

    In 1940, during his second year of medical training, Jim Tanner expressed the desire to work, 'where physiology, psychology and sociology meet'. His subsequent exposure to the breadth of an American medical education and to the social and economic environment of post-war Europe distilled his belief in the importance of viewing the human in a broad context. Following his visits to the American longitudinal growth studies in 1948. Jim's dreams of a broad scientific discipline that incorporated both the biology and ecology of the human were strengthened by an inspirational group of embryonic human biologists with whom he developed '… the new Human Biology …' from the '… Physical Anthropology of old…'. With Jo Weiner, Derek Roberts, Geoffrey Harrison, Arthur Mourant, Nigel Barnicot and Kenneth Oakley, Jim was to form the Society for the Study of Human Biology in 1958. The development of human biology over the next 50 years was shaped by the expertise and diversity of that group of visionary scientists who conceived the scientific discipline of 'human biology' in which biology, behaviour and social context define the human species.

  14. Optimal codes as Tanner codes with cyclic component codes

    DEFF Research Database (Denmark)

    Høholdt, Tom; Pinero, Fernando; Zeng, Peng

    2014-01-01

    In this article we study a class of graph codes with cyclic code component codes as affine variety codes. Within this class of Tanner codes we find some optimal binary codes. We use a particular subgraph of the point-line incidence plane of A(2,q) as the Tanner graph, and we are able to describe...... the codes succinctly using Gröbner bases....

  15. Conventional Tanner Graph for Recursive onvolutional Codes and Associated Decoding

    Institute of Scientific and Technical Information of China (English)

    SUN Hong

    2001-01-01

    A different representation of recur-sive systematic convolutional (RSC) codes is pro-posed. This representation can be realized by a con-ventional Tanner graph. The graph becomes a treeby introducing hidden edge. It is shown that thesum-product algorithm applied to this graph modelis equivalent to the BCJR algorithm for turbo de-coding with lower computational complexity. Themessage-passing chain of the BCJR algorithm is pre-sented more exactly in the graph. In addition, theproposed representation of RSC codes provides an ef-ficient method to set up the trellis and the conven-tional Tanner graph for RSC codes provides directlythe architecture for decoding.

  16. Siim Nestor soovitab : Goldie. Chris Simmonds / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2002-01-01

    Drum'n'bassi esimese superstaari Goldie esinemisest 16. nov. Circulation-sarja peol Lillepaviljonis Tallinnas. Londoni diskori Chris Simmondsi esinemistest 15. nov. Tartu klubis Tallinn ja 16. nov. Tallinnas kohvikus Moskva

  17. Siim Nestor soovitab : Goldie. Chris Simmonds / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2002-01-01

    Drum'n'bassi esimese superstaari Goldie esinemisest 16. nov. Circulation-sarja peol Lillepaviljonis Tallinnas. Londoni diskori Chris Simmondsi esinemistest 15. nov. Tartu klubis Tallinn ja 16. nov. Tallinnas kohvikus Moskva

  18. Calibratio performance evaluation of the spaceborne hyperspectral CHRIS imager

    Institute of Scientific and Technical Information of China (English)

    ZHANG; Xia; ZHANG; Bing; HU; Fangchao; TONG; Qingxi

    2006-01-01

    The CHRIS (Compact High Resolution Imaging Spectrometer) is a new imaging spectrometer, carried on board a new space platform called PROBA (Project for On Board Autonomy). The satellite was successfully launched in October 2001 by the European Space Agency (ESA). CHRIS operates over the visible/near infrared band (400-1050 nm). It has five work modes and can reach a maximum of 62 spectral bands. In this research, atmospheric correction based on hyperspectral images was performed on CHRIS images by using the popular radiance transfer code ACORN (Atmospheric Correction Now) and empirical algorithms. ACORN was also used to evaluate the calibration performance of CHRIS by the retrieved spectra of typical vegetation and soil. As a result,the maize reflectance spectrum corrected by ACORN could characterize vegetation reflectance in the range of 498-750 nm, but gave a fairly large deviation beyond 750 nm,showing the deficiency of spectral calibration beyond 750 nm. The ACORN-derived soil reflectance decreased beyond 800 nm, which was quite inconsistent with field-spectrummeasurement and showed that the calibration accuracy couldn't meet the requirements of ACORN for spectral and radiometric calibration within a certain spectral range. In addition,the stripes on the retrieved water-vapor content map indicated that the radiance-calibration performance of CHRIS is not perfect. As the first spaceborne hyperspectral imager of ESA, the calibration performance of CHRIS needs to be improved.

  19. Patrick Leigh Fermor’s “Hellen-Romaic Dilemma”

    Directory of Open Access Journals (Sweden)

    Przemysław Kordos

    2015-07-01

    The article discusses one of the guises of the dichotomy between Hellene and Romios, a trope popular among researchers of modern Greek identity. It discusses the provenance and usage of both notions, drawing on the material presented by the English traveller and writer Patrick Leigh Fermor in his monograph Roumeli Travels in Northern Greece (1966. Fermor identified 64 opposing pairs of concepts and situations, and demonstrated the characteristics of Hellene and Romios in relation to each pair. This comparison produces the images of the logical, westernised Hellene, who reveres the accomplishments of ancient Greeks, and the spontaneous, oriental, somewhat backwards Romios, who longs for Byzantium. Although the picture Fermor paints is exaggerated (and slightly whimsical, it nevertheless helps to understand that the image of Hellene, and not that of Romios, is one in which modern Greeks believe and for which they strive. Patricka Leigh Fermora rozterki helleńsko-romejskie Autor omawia jedno z ujęć dychotomii między Hellenem a Romiosem, popularnej w badaniach nad nowogrecką tożsamością. Ukazuje proweniencję i sposób użycia obu pojęć, posługując się materiałem zaprezentowanym przez angielskiego pisarza i podróżnika, Patricka Leigh Fermora, w jego monografii Roumeli Travels in Northern Greece (wyd. 1966. Fermor wyróżnił 64 pary koncepcji i sytuacji, pokazując jak w obrębie każdej z nich funkcjonuje Hellen oraz Romios. Z porównania wyłania się obraz logicznego, zwesternizowanego Hellena, zapatrzonego w dokonania starożytnych Greków oraz spontanicznego, orientalnego, nieco zacofanego Romiosa, który tęskni za Bizancjum. Choć obraz naszkicowany przez Fermora jest przejaskrawiony (oraz nieco żartobliwy, to jednak pomaga zrozumieć, że to obraz Hellena, a nie Romiosa, jest tym, w który wierzą i do którego dążą współcześni Grecy.

  20. [The Durkheim Test. Remarks on Susan Leigh Star's Boundary Objects].

    Science.gov (United States)

    Gießmann, Sebastian

    2015-09-01

    The article reconstructs Susan Leigh Star's conceptual work on the notion of 'boundary objects'. It traces the emergence of the concept, beginning with her PhD thesis and its publication as Regions of the Mind in 1989. 'Boundary objects' attempt to represent the distributed, multifold nature of scientific work and its mediations between different 'social worlds'. Being addressed to several 'communities of practice', the term responded to questions from Distributed Artificial Intelligence in Computer Science, Workplace Studies and Computer Supported Cooperative Work (CSCW), and microhistorical approaches inside the growing Science and Technology Studies. Yet the interdisciplinary character and interpretive flexibility of Star’s invention has rarely been noticed as a conceptual tool for media theory. I therefore propose to reconsider Star's 'Durkheim test' for sociotechnical media practices.

  1. Long survival in leigh syndrome: new cases and review of literature

    NARCIS (Netherlands)

    Aulbert, W.; Weigt-Usinger, K.; Thiels, C.; Kohler, C.; Vorgerd, M.; Schreiner, A.; Hoffjan, S.; Rothoeft, T.; Wortmann, S.B.; Heyer, C.M.; Podskarbi, T.; Lucke, T.

    2014-01-01

    Leigh syndrome (MIM 25600), also known as infantile subacute necrotizing encephalomyelopathy, is a neurodegenerative disorder with characteristic bilateral symmetric lesions in basal ganglia and subcortical brain regions. It is commonly associated with systemic cytochrome c oxidase (COX) deficiency

  2. Spectrodirectional Minnaert-k retrieval using CHRIS-PROBA data

    NARCIS (Netherlands)

    Verrelst, J.; Schaepman, M.E.; Clevers, J.G.P.W.

    2010-01-01

    We report on a detailed analysis of hyperspectral and multidirectional remote sensing data acquired using the Compact High Resolution Imaging Spectrometer (CHRIS) mounted onboard the Project for On-Board Autonomy (PROBA) spacecraft. This instrument is capable of sampling reflected radiation over the

  3. Emerging Perspectives on Editorial Ethics: An Interview with Chris Higgins

    Science.gov (United States)

    Jackson, Liz

    2017-01-01

    Chris Higgins took on the roles of Editor of "Educational Theory," and Editor-in-Chief of the "Philosophy of Education Yearbook" published by the Philosophy of Education Society, in 2013, after having been an Associate Editor and Book Review Editor for "Educational Theory" for six years. Higgins worked closely with…

  4. Chris Woodhead: A New Champion of Eugenic Theories

    Science.gov (United States)

    Chitty, Clyde

    2009-01-01

    Eugenic Theories are clearly alive and well in present-day society--or this is at least true of those theories relating to the passing on of abilities and talents from one generation to the next. This depressing thought was prompted by a reading of Chris Woodhead's latest book "A Desolation of Learning."

  5. Spectrodirectional Minnaert-k retrieval using CHRIS-PROBA data

    NARCIS (Netherlands)

    Verrelst, J.; Schaepman, M.E.; Clevers, J.G.P.W.

    2010-01-01

    We report on a detailed analysis of hyperspectral and multidirectional remote sensing data acquired using the Compact High Resolution Imaging Spectrometer (CHRIS) mounted onboard the Project for On-Board Autonomy (PROBA) spacecraft. This instrument is capable of sampling reflected radiation over the

  6. Leigh syndrome. A comparison of CT scanning and pathological findings

    Energy Technology Data Exchange (ETDEWEB)

    Hirata, Y.; Okamoto, K.; Somiya, K. (Hamamatsu Medical Center, Shizuoka (Japan)); Hokazono, Y.; Tozuka, S.

    1981-11-01

    A male infant developed hypotonia at 5 months, vomiting, diarrhea, fever, generalized clonic convulsion, tonic spasm and periodical opisthotonus at 8 months, swallowing difficulty at 10 months, pes equinovarus and optic atrophy at 11 months, and then tachypnea, and died at 14 months of age. Parents were consanguinous. Laboratory studies revealed elevated serum LDH, CPK, lactate and Pyruvate. TPP-ATP phosphoryl transferase inhibitor was negative in urine. EEG showed irregular and diffuse slow waves and periodic diffuse spike and waves. CT scan at 9 months of age showed slightly low attenuation areas in the putamen bilaterally. At 11 months, a diffuse cerebral atrophy was found, and the low attenuation of the basal ganglia became more definite. No enhanced lesion was seen at 13 months of age. Thiamine tetra-hydrofurfuryl disulfide and lipoic acid were tried without success. The pathological findings of the brain were astrogliosis and proliferation of capillaries in putamen, thalamus, caudate nucleus, substantia nigra, pontine brachium and cerebral cortex, which were symmetrically involved. The symmetrical cavitation was found in putamen. Optic nerve and mamillary body were spared. CT scan findings corresponded well with the pathology of the necrotic lesions of the brain. It was concluded that these CT scan pictures described above may be diagnostic of Leigh syndrome.

  7. Leigh-Like Syndrome Due to Homoplasmic m.8993T>G Variant with Hypocitrullinemia and Unusual Biochemical Features Suggestive of Multiple Carboxylase Deficiency (MCD)

    NARCIS (Netherlands)

    Balasubramaniam, S.; Lewis, B.; Mock, D.M.; Said, H.M.; Tarailo-Graovac, M.; Mattman, A.; Karnebeek, C.D; Thorburn, D.R.; Rodenburg, R.J.T.; Christodoulou, J.

    2017-01-01

    Leigh syndrome (LS), or subacute necrotizing encephalomyelopathy, is a genetically heterogeneous, relentlessly progressive, devastating neurodegenerative disorder that usually presents in infancy or early childhood. A diagnosis of Leigh-like syndrome may be considered in individuals who do not

  8. The neuroimaging of Leigh syndrome: case series and review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Bonfante, Eliana; Riascos, Roy F. [The University of Texas Medical School at Houston, Department of Diagnostic and Interventional Imaging, Houston, TX (United States); Koenig, Mary Kay [The University of Texas Medical School at Houston, Department of Pediatrics, Division of Child and Adolescent Neurology, Mitochondrial Center of Excellence Leigh Clinic, Houston, TX (United States); Adejumo, Rahmat B.; Perinjelil, Vinu [The University of Texas Medical School at Houston, Department of Pediatrics, Division of Child and Adolescent Neurology, Houston, TX (United States)

    2016-04-15

    Leigh syndrome by definition is (1) a neurodegenerative disease with variable symptoms, (2) caused by mitochondrial dysfunction from a hereditary genetic defect and (3) accompanied by bilateral central nervous system lesions. A genetic etiology is confirmed in approximately 50% of patients, with more than 60 identified mutations in the nuclear and mitochondrial genomes. Here we review the clinical features and imaging studies of Leigh syndrome and describe the neuroimaging findings in a cohort of 17 children with genetically confirmed Leigh syndrome. MR findings include lesions in the brainstem in 9 children (53%), basal ganglia in 13 (76%), thalami in 4 (24%) and dentate nuclei in 2 (12%), and global atrophy in 2 (12%). The brainstem lesions were most frequent in the midbrain and medulla oblongata. With follow-up an increased number of lesions from baseline was observed in 7 of 13 children, evolution of the initial lesion was seen in 6, and complete regression of the lesions was seen in 3. No cerebral white matter lesions were found in any of the 17 children. In concordance with the literature, we found that Leigh syndrome follows a similar pattern of bilateral, symmetrical basal ganglia or brainstem changes. Lesions in Leigh syndrome evolve over time and a lack of visible lesions does not exclude the diagnosis. Reversibility of lesions is seen in some patients, making the continued search for treatment and prevention a priority for clinicians and researchers. (orig.)

  9. MS Noriega and Tanner check out STS-97 payload

    Science.gov (United States)

    2000-01-01

    In the Space Station Processing Facility, STS-97 Mission Specialists Carlos Noriega (left) and Joe Tanner check out the mission payload, the P6 integrated truss segment. Mission STS-97 is the sixth construction flight to the International Space Station. The P6 comprises Solar Array Wing-3 and the Integrated Electronic Assembly, to be installed on the International Space Station. The Station's electrical power system will use eight photovoltaic solar arrays, each 112 feet long by 39 feet wide, to convert sunlight to electricity. The solar arrays are mounted on a '''blanket''' that can be folded like an accordion for delivery. Once in orbit, astronauts will deploy the blankets to their full size. Gimbals will be used to rotate the arrays so that they will face the Sun to provide maximum power to the Space Station. The mission includes two spacewalks by Noriega and Tanner to complete the solar array connections. STS-97 is scheduled to launch Nov. 30 at about 10:06 p.m. EST.

  10. Come to Daddy? Claiming Chris Cunningham for British Art Cinema

    OpenAIRE

    Leggott, James

    2016-01-01

    Twenty years after he came to prominence via a series of provocative, ground-breaking music videos, Chris Cunningham remains a troubling, elusive figure within British visual culture. His output – which includes short films, advertisements, art gallery commissions, installations, music production and a touring multi-screen live performance – is relatively slim, and his seemingly slow work rate (and tendency to leave projects uncompleted or unreleased) has been a frustration for fans and comme...

  11. Gait analysis in a mouse model resembling Leigh disease.

    Science.gov (United States)

    de Haas, Ria; Russel, Frans G; Smeitink, Jan A

    2016-01-01

    Leigh disease (LD) is one of the clinical phenotypes of mitochondrial OXPHOS disorders and also known as sub-acute necrotizing encephalomyelopathy. The disease has an incidence of 1 in 77,000 live births. Symptoms typically begin early in life and prognosis for LD patients is poor. Currently, no clinically effective treatments are available. Suitable animal and cellular models are necessary for the understanding of the neuropathology and the development of successful new therapeutic strategies. In this study we used the Ndufs4 knockout (Ndufs4(-/-)) mouse, a model of mitochondrial complex I deficiency. Ndusf4(-/-) mice exhibit progressive neurodegeneration, which closely resemble the human LD phenotype. When dissecting behavioral abnormalities in animal models it is of great importance to apply translational tools that are clinically relevant. To distinguish gait abnormalities in patients, simple walking tests can be assessed, but in animals this is not easy. This study is the first to demonstrate automated CatWalk gait analysis in the Ndufs4(-/-) mouse model. Marked differences were noted between Ndufs4(-/-) and control mice in dynamic, static, coordination and support parameters. Variation of walking speed was significantly increased in Ndufs4(-/-) mice, suggesting hampered and uncoordinated gait. Furthermore, decreased regularity index, increased base of support and changes in support were noted in the Ndufs4(-/-) mice. Here, we report the ability of the CatWalk system to sensitively assess gait abnormalities in Ndufs4(-/-) mice. This objective gait analysis can be of great value for intervention and drug efficacy studies in animal models for mitochondrial disease.

  12. Mutated ND2 impairs mitochondrial complex I assembly and leads to Leigh syndrome.

    NARCIS (Netherlands)

    Ugalde, C.; Hinttala, R.; Timal, S.; Smeets, R.; Rodenburg, R.J.T.; Uusimaa, J.; Heuvel, L.P.W.J. van den; Nijtmans, L.G.J.; Majamaa, K.; Smeitink, J.A.M.

    2007-01-01

    We describe a novel mitochondrial ND2 mutation (T4681C) in a patient presenting with Leigh Syndrome. Biochemical analyses revealed a low isolated complex I activity in patient's fibroblasts, blood and skeletal muscle. Mutant transmitochondrial cybrid clones retained the specific complex I defect,

  13. Clinical and laboratory survey of 65 Chinese patients with Leigh syndrome

    Institute of Scientific and Technical Information of China (English)

    YANG Yan-ling; QI Zhao-yue; ZHANG Yue-hua; JIANG Yu-wu; BAO Xin-hua; QIN Jiong; WU Xi-ru; SUN Fang; ZHANG Yao; QIAN Ning; YUAN Yun; WANG Zhao-xia; QI Yu; XIAO Jiang-xi; WANG Xiao-ying

    2006-01-01

    Background Leigh syndrome is an inherited neurodegenerative disease that emerges in infancy and childhood and presents with a clinically heterogeneous variety of neuromuscular and non-neuromuscular disorders. It can result from the inheritance of mutations in either nuclear or mitochondrial DNA. In the current study, we performed a retrospective study in 65 patients in order to investigate the clinical and genetic characteristics of Leigh syndrome in Chinese patients.Methods Sixty-five unrelated cases (35 men and 30 women) who were hospitalized in the past 12 years were reviewed. Diagnosis was based on both the clinical presentation and the characteristic neuropathologic findings of bilateral symmetric necrotizing lesions in the basal ganglia and brain stem as detected using cranial computed tomography (CT) scan or magnetic resonance imaging (MRI). The differential diagnosis of organic acidurias and fatty acid β-oxidation defects were performed. Specific point mutations and deletions in mitochondrial DNA (T8993G, T8993C, T9176C, A8344G, A3243G) were screened by PCR-restriction analysis and Southern blot.The SURF1 gene was sequenced. Skeletal muscle biopsies were performed in 17 (26.2%) of the patients. The diagnosis was confirmed by autopsy in 6 (9.2%) patients.Results The patients had various forms of metabolic encephalomyopathy. Fifty-nine (90.8%) of the patients had the typical neuroradiological features of Leigh syndrome, including symmetrical necrotizing lesions scattered within the basal ganglia, thalamus and brain stem. Twenty (30.8%) patients were confirmed by genetic,biochemical analysis and autopsy. Specific point mutations in mitochondrial DNA were found in 5 cases (7.7%).Of these, the A8344G mutation was detected in 2 patients. The T8993G, T8993C, and A3243G point mutations were identified in 3 other patients, respectively. SURF1 mutations associated with cytochrome c oxidase deficiency were identified in 8 (12.3%) families by DNA sequencing. A G604C

  14. AFSC/RACE/SAP/Munk: Life history studies of Tanner crab, Chionoecetes bairdi, near Kodiak, Alaska.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — From 1994 through 2012 Tanner crab were identified as premolt, held through a molt, and then measured to determine growth per molt.

  15. AFSC/RACE/SAP/Foy: Effects of ocean acidification on larval Tanner crab: Kodiak Island, Alaska.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — To study the effects of ocean acidification we examined the effects of ocean acidification on the larval stages of the economically important southern Tanner crab,...

  16. AFSC/RACE/SAP/Jensen: Bitter crab disease mortality in SE Alaska Tanner crab

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These are data from a laboratory experiment in which wild caught male Tanner crab (Chionoecetes bairdi) from Stephens Passage, SE Alaska were held to evaluate crab...

  17. [A case of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episode/Leigh overlap syndrome].

    Science.gov (United States)

    Matsui, Jun; Takano, Tomoyuki; Ryujin, Fukiko; Anzai, Yuko; Yoshioka, Seiichiro; Takeuchi, Yoshihiro; Goto, Yuichi

    2014-09-01

    We experienced a case in which mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) was identified as complications following the onset of Leigh syndrome along with a 10191 T>C mutation of the mitochondrial gene. The case pertains to a 26-year-old woman. The disease appeared when she was 11 years old due to divergent strabismus, at which point a diagnosis of juvenile Leigh syndrome was made. Many infraction images not conforming to the vessel region were observed upon a brain MRI which was performed at 26 years of age, thus leading to her being diagnosed with MELAS as a complication. Upoon bibliographical consideration, it was speculated that the clinical features of MELAS/Leigh overlap syndrome clearly differ from Leigh syndrome in terms of age of onset, symptoms, and prognosis. Pleiotropic genetic factors including heteroplasmy were presumed to be involved in the diverse phenotype of overlap syndrome.

  18. Chris Hughes的第三次行动

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Facebook创始人之一Chris Hughes目前已经加入了一家位于波斯顿的名叫General Catalyst的风险投资公司。这家公司管理着18亿美元的资产,已经投资了65家公司,其中包括Kayak及Brightcove等公司。“我们在一年前曾关闭了一家价值7亿1500万美元的基金公司,”这家公司的常务董事Neil Sequeira说,“我们的投资非常活跃。现在非常高兴Chris加盟我们。”

  19. Fundamentals of Seismic Wave Propagation by Chris Chapman

    Science.gov (United States)

    Aster, Richard

    2005-03-01

    The analytic characterization and modeling of seismic wave propagation using ray theory based formulations is a core aspect of seismology with a distinguished and very important history. Fundamentals of Seismic Wave Propagation, by Chris Chapman, provides a mathematically rigorous and substantially complete summary of theory and techniques, with exercises, written at an accessible level for intermediate-to-advanced seismology graduate students and for the general research community. I was particularly pleased to see that much relevant mathematics is well summarized in a valuable ``preliminaries'' section containing mathematical and physics background material, coupled with four focused mathematical Appendices covering relevant integrals, Fourier transforms, ordinary differential equations, and saddle-point methods. This bodes well for the text as a teaching resource.

  20. Chris Lamb: a visionary leader in plant science.

    Science.gov (United States)

    Dixon, Richard A

    2011-01-01

    Christopher John Lamb (1950-2009) made major contributions to the field of plant defense gene activation, particularly through his studies on signal transduction mechanisms. Between 1994 and 2004, he published a series of seminal papers that outlined the involvement of hydrogen peroxide, nitric oxide, lipid transfer proteins, and aspartic proteases as critical components of local and/or systemic resistance during plant-microbe interactions. Prior to this, he had been one of the first to establish the fact that induced defense responses resulted from transcriptional activation of sets of coordinately regulated genes. Chris obtained his B.S and PhD degrees in biochemistry from the University of Cambridge, United Kingdom, moving to the Botany School at the University of Oxford as a postdoctoral fellow in 1975 and to the Biochemistry Department in Oxford as a Departmental Demonstrator in 1978. He was appointed founding director of the Plant Biology Laboratory at the Salk Institute for Biological Studies in La Jolla, California in 1982, and occupied the last ten years of his life as Director of the John Innes Center, Norwich, United Kingdom. In spite of spending most of his career as a director at two of the world's most prestigious institutes, formal recognition of his achievements came late in life, with election to the Royal Society of London in 2008 and endowment of the honor of Commander of the British Empire (CBE) for his contributions to British plant science by Queen Elizabeth II in 2009. Sadly, Chris did not live to attend the official ceremony at which he would receive his CBE.

  1. Mike Leigh' abordi-draama võitis Veneetsias Kuldlõvi / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2004-01-01

    Veneetsia 61. filmifestivali võitjad : Kuldlõvi sai inglase Mike Leigh "Vera Drake" (nimiosa eest ka parima naisnäitleja Coppa Volpi Imelda Stauntonile), Hõbelõvi läks hispaanlase Alejandro Amenabari filmile "Merele" (siit ka parima meesnäitleja au Javier Bardemile), režii eriauhinna sai Kim Ki-duk Lõuna-Koreast filmiga "Tühi maja" ("Bin jip")

  2. Mike Leigh' abordi-draama võitis Veneetsias Kuldlõvi / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2004-01-01

    Veneetsia 61. filmifestivali võitjad : Kuldlõvi sai inglase Mike Leigh "Vera Drake" (nimiosa eest ka parima naisnäitleja Coppa Volpi Imelda Stauntonile), Hõbelõvi läks hispaanlase Alejandro Amenabari filmile "Merele" (siit ka parima meesnäitleja au Javier Bardemile), režii eriauhinna sai Kim Ki-duk Lõuna-Koreast filmiga "Tühi maja" ("Bin jip")

  3. Leigh Wilson, Modernism and Magic. Experiments with Spiritualism, Theosophy and the Occult

    OpenAIRE

    Marie, Florence

    2015-01-01

    In her 167-page book entitled Modernism and Magic. Experiments with Spiritualism, Theosophy and the Occult, Leigh Wilson tries to understand in what respect a certain number of modernist writers’ and avant-garde artists’ interest in theosophy, spiritualism and occult practices influenced their creations. She argues that in many cases their interest enabled them to define a new approach to mimesis without rejecting the latter altogether. She contends that magic was at the heart of the occult d...

  4. ECHS1 mutations in Leigh disease: a new inborn error of metabolism affecting valine metabolism.

    Science.gov (United States)

    Peters, Heidi; Buck, Nicole; Wanders, Ronald; Ruiter, Jos; Waterham, Hans; Koster, Janet; Yaplito-Lee, Joy; Ferdinandusse, Sacha; Pitt, James

    2014-11-01

    Two siblings with fatal Leigh disease had increased excretion of S-(2-carboxypropyl)cysteine and several other metabolites that are features of 3-hydroxyisobutyryl-CoA hydrolase (HIBCH) deficiency, a rare defect in the valine catabolic pathway associated with Leigh-like disease. However, this diagnosis was excluded by HIBCH sequencing and normal enzyme activity. In contrast to HIBCH deficiency, the excretion of 3-hydroxyisobutyryl-carnitine was normal in the children, suggesting deficiency of short-chain enoyl-CoA hydratase (ECHS1 gene). This mitochondrial enzyme is active in several metabolic pathways involving fatty acids and amino acids, including valine, and is immediately upstream of HIBCH in the valine pathway. Both children were compound heterozygous for a c.473C > A (p.A158D) missense mutation and a c.414+3G>C splicing mutation in ECHS1. ECHS1 activity was markedly decreased in cultured fibroblasts from both siblings, ECHS1 protein was undetectable by immunoblot analysis and transfection of patient cells with wild-type ECHS1 rescued ECHS1 activity. The highly reactive metabolites methacrylyl-CoA and acryloyl-CoA accumulate in deficiencies of both ECHS1 and HIBCH and are probably responsible for the brain pathology in both disorders. Deficiency of ECHS1 or HIBCH should be considered in children with Leigh disease. Urine metabolite testing can detect and distinguish between these two disorders.

  5. LRPPRC mutations cause a phenotypically distinct form of Leigh syndrome with cytochrome c oxidase deficiency.

    Science.gov (United States)

    Debray, François-Guillaume; Morin, Charles; Janvier, Annie; Villeneuve, Josée; Maranda, Bruno; Laframboise, Rachel; Lacroix, Jacques; Decarie, Jean-Claude; Robitaille, Yves; Lambert, Marie; Robinson, Brian H; Mitchell, Grant A

    2011-03-01

    The natural history of all known patients with French-Canadian Leigh disease (Saguenay-Lac-St-Jean cytochrome c oxidase deficiency, MIM220111, SLSJ-COX), the largest known cohort of patients with a genetically homogeneous, nuclear encoded congenital lactic acidosis, was studied. 55 of 56 patients were homozygous for the A354V mutation in LRPPRC. One was a genetic compound (A354V/C1277Xdel8). Clinical features included developmental delay, failure to thrive, characteristic facial appearance and, in 90% of patients, acute crises that have not previously been detailed, either metabolic (fulminant lactic acidosis) and/or neurological (Leigh syndrome and/or stroke-like episodes). Survival ranged from 5 days to >30 years. 46/56 patients (82%) died, at a median age of 1.6 years. Of 73 crises, 38 (52%) were fatal. The immediate causes of death were multiple organ failure and/or Leigh disease. Major predictors of mortality during crises (pgenetic and/or environmental factors can influence outcome.

  6. On 20 November CERN hosted a symposium to mark the 70th birthday of Chris Llewellyn Smith

    CERN Multimedia

    Maximilien Brice

    2012-01-01

    Left to right: (back) Rolf Heuer, Peter Jenni, Lyn Evans, Chris Llewellyn Smith, Steve Cowley, Zehra Sayers, David Gross, Chris Allsopp, Robert Jaffe, Bikash Sinha; (front) Geoffrey West, Álvaro de Rújula, John Ellis.

  7. Accuracy improvement of geometric correction for CHRIS data

    Institute of Scientific and Technical Information of China (English)

    WANG Dian-zhong; PANG Yong; GUO Zhi-feng

    2008-01-01

    This paper deals with a new type of multi-angle remotely sensed data---CHRIS (the Compact High Resolution Imaging Spectrometer), by using rational function models (RFM) and rigorous sensor models (RSM). For ortho-rectifying an image set, a rigorous sensor model-Toutin's model was employed and a set of reported parameters including across track angle, along track angle, IFOV, altitude, period, eccentricity and orbit inclination were input, then, the orbit calculation was started and the track information was given to the raw data. The images were ortho-rectified with geocoded ASTER images and digital elevation (DEM) data. Results showed that with 16 ground control points (GCPs), the correction accuracy decreased with view zenith angle, and the RMSE value increased to be over one pixel at 36 degree off-nadir. When the GCPs were approximately chosen as in Toutin's model, a RFM with three coefficients produced the same accuracy trend versus view zenith angle while the RMSEs for all angles were improved and within about one pixel.

  8. A single cell complementation class is common to several cases of cytochrome c oxidase-defective Leigh's syndrome.

    Science.gov (United States)

    Munaro, M; Tiranti, V; Sandonà, D; Lamantea, E; Uziel, G; Bisson, R; Zeviani, M

    1997-02-01

    A generalized defect of complex IV (cytochrome C oxidase, COX) is frequently found in subacute necrotizing encephalomyelopathy (Leigh's syndrome), the most common mitochondrial disorder in infancy. We previously demonstrated the nuclear origin of the COX defect in one case, by fusing nuclear DNA-less cytoplasts derived from normal fibroblasts with mitochondrial DNA (mtDNA)-less transformant fibroblasts derived from a patient with COX-defective [COX(-)] Leigh's syndrome. The resulting cybrid line showed a specific and serve COX(-) phenotype. Conversely, in the present study, we demonstrated that a COX(+) phenotype could be restored in hybrids obtained by fusing COX(-) transformant fibroblasts of seven additional Leigh's syndrome patients with mtDNA-less, COX(-) tumor-derived rho degree cells. Both these results are explained by the presence of a mutation in a nuclear gene. In a second set of experiments, in order to demonstrate whether COX(-) Leigh's syndrome is due to a defect in the same gene, or in different genes, we tested several hybrids derived by fusing our original COX(-) cell line with each of the remaining seven cell lines. COX activity was evaluated in situ by histochemical techniques and in cell extracts by a spectrophotometric assay. No COX complementers were found among the resulting hybrid lines. This result demonstrates that all our cases were genetically homogeneous, and suggests that a major nuclear disease locus is associated with several, perhaps most, of the cases of infantile COX(-) Leigh's syndrome. This information should make it easier to identify the gene responsible.

  9. Mental health problems during puberty: Tanner stage-related differences in specific symptoms. The TRAILS study

    OpenAIRE

    Albertine J Oldehinkel; Verhulst, Frank C.; Ormel, Johan

    2011-01-01

    The aim of this study was to investigate associations between specific mental health problems and pubertal stage in (pre)adolescents participating in the Dutch prospective cohort study TRAILS (first assessment: N = 2230, age 11.09 +/- 0.56, 50.8% girls; second assessment: N = 2149, age 13.56 +/- 0.53, 51.0% girls). Mental health was assessed by the Youth Self-Report, pubertal (Tanner) stage by parent-rated drawings of secondary sex characteristics. Overall, higher Tanner stages were related t...

  10. Accurate LAI retrieval method based on PROBA/CHRIS data

    Directory of Open Access Journals (Sweden)

    W. Fan

    2009-11-01

    Full Text Available Leaf area index (LAI is one of the key structural variables in terrestrial vegetation ecosystems. Remote sensing offers a chance to derive LAI in regional scales accurately. Variations of background, atmospheric conditions and the anisotropy of canopy reflectance are three factors that can strongly restrain the accuracy of retrieved LAI. Based on the hybrid canopy reflectance model, a new hyperspectral directional second derivative method (DSD is proposed in this paper. This method can estimate LAI accurately through analyzing the canopy anisotropy. The effect of the background can also be effectively removed. So the inversion precision and the dynamic range can be improved remarkably, which has been proved by numerical simulations. As the derivative method is very sensitive to the random noise, we put forward an innovative filtering approach, by which the data can be de-noised in spectral and spatial dimensions synchronously. It shows that the filtering method can remove the random noise effectively; therefore, the method can be performed to the remotely sensed hyperspectral image. The study region is situated in Zhangye, Gansu Province, China; the hyperspectral and multi-angular image of the study region has been acquired from Compact High-Resolution Imaging Spectrometer/Project for On-Board Autonomy (CHRIS/PROBA, on 4 and 14 June 2008. After the pre-processing procedures, the DSD method was applied, and the retrieve LAI was validated by the ground truth of 11 sites. It shows that by applying innovative filtering method, the new LAI inversion method is accurate and effective.

  11. Mutations of SURF-1 in Leigh disease associated with cytochrome c oxidase deficiency.

    OpenAIRE

    1998-01-01

    Leigh disease associated with cytochrome c oxidase deficiency (LD[COX-]) is one of the most common disorders of the mitochondrial respiratory chain, in infancy and childhood. No mutations in any of the genes encoding the COX-protein subunits have been identified in LD(COX-) patients. Using complementation assays based on the fusion of LD(COX-) cell lines with several rodent/human rho0 hybrids, we demonstrated that the COX phenotype was rescued by the presence of a normal human chromosome 9. L...

  12. Atypical presentation of Leigh syndrome associated with a Leber hereditary optic neuropathy primary mitochondrial DNA mutation.

    Science.gov (United States)

    Fruhman, Gary; Landsverk, Megan L; Lotze, Timothy E; Hunter, Jill V; Wangler, Michael F; Adesina, Adekunle M; Wong, Lee-Jun C; Scaglia, Fernando

    2011-06-01

    Leber hereditary optic neuropathy (LHON) is caused by point mutations in mitochondrial DNA (mtDNA), and is characterized by bilateral, painless sub-acute visual loss that develops during the second decade of life. Here we report the case of a five year old girl who presented with clinical and neuroradiological findings reminiscent of Leigh syndrome but carried a mtDNA mutation m.11778G>A (p.R340H) in the MTND4 gene usually observed in patients with LHON. This case is unusual for age of onset, gender, associated neurological findings and evolution, further expanding the clinical spectrum associated with primary LHON mtDNA mutations.

  13. Second-degree burns caused by exposure to sunbed with displaced filter in the facial tanner

    DEFF Research Database (Denmark)

    Faurschou, Annesofie; Heydenreich, Jakob; Wulf, Hans Christian

    2013-01-01

    Sunbed exposure frequently leads to erythema of the skin but second-degree burns are unusual. We report two patients who experienced second-degree burns due to partial displacement of the filter in the facial tanner of a sunbed. This is a severe fault and calls for increased safety regulations....

  14. Post-Tanner stages of droplet spreading: the energy balance approach revisited

    Energy Technology Data Exchange (ETDEWEB)

    Mechkov, S; Oshanin, G [Laboratoire de Physique Theorique de la Matiere Condensee, Universite Pierre et Marie Curie, 4 place Jussieu, 75252 Paris Cedex 5 (France); Cazabat, A M, E-mail: mechkov@lptmc.jussieu.f, E-mail: anne-marie.cazabat@lps.ens.f, E-mail: oshanin@lptmc.jussieu.f [Laboratoire de Physique Statistique, Ecole Normale Superieure, 75252 Paris Cedex 5 (France)

    2009-11-18

    The spreading of a circular liquid drop on a solid substrate can be described in terms of the time evolution of its base radius R(t). In complete wetting, the quasistationary regime (far away from initial and final transients) typically obeys the so-called Tanner law, with Rapproxt{sup alpha}{sub T}, alpha{sub T} = 1/10. Late-time spreading may differ significantly from the Tanner law: in some cases the drop does not thin down to a molecular film and instead reaches an equilibrium pancake-like shape; in other situations, as revealed by recent experiments with spontaneously spreading nematic crystals, the growth of the base radius accelerates after the Tanner stage. Here we demonstrate that these two seemingly conflicting trends can be reconciled within a suitably revisited energy balance approach, by taking into account the line tension contribution to the driving force of spreading: a positive line tension is responsible for the formation of pancake-like structures, whereas a negative line tension tends to lengthen the contact line and induces an accelerated spreading (a transition to a faster power law for R(t) than in the Tanner stage).

  15. Post-Tanner stages of droplet spreading: the energy balance approach revisited.

    Science.gov (United States)

    Mechkov, S; Cazabat, A M; Oshanin, G

    2009-11-18

    The spreading of a circular liquid drop on a solid substrate can be described in terms of the time evolution of its base radius R(t). In complete wetting, the quasistationary regime (far away from initial and final transients) typically obeys the so-called Tanner law, with R∼t(α(T)), α(T) = 1/10. Late-time spreading may differ significantly from the Tanner law: in some cases the drop does not thin down to a molecular film and instead reaches an equilibrium pancake-like shape; in other situations, as revealed by recent experiments with spontaneously spreading nematic crystals, the growth of the base radius accelerates after the Tanner stage. Here we demonstrate that these two seemingly conflicting trends can be reconciled within a suitably revisited energy balance approach, by taking into account the line tension contribution to the driving force of spreading: a positive line tension is responsible for the formation of pancake-like structures, whereas a negative line tension tends to lengthen the contact line and induces an accelerated spreading (a transition to a faster power law for R(t) than in the Tanner stage).

  16. Spatial patterns and movements of red king and Tanner crabs: Implications for the design of marine protected areas

    Science.gov (United States)

    Taggart, S.J.; Mondragon, J.; Andrews, A.G.; Nielsen, J.K.

    2008-01-01

    Most examples of positive population responses to marine protected areas (MPAs) have been documented for tropical reef species with very small home ranges; the utility of MPAs for commercially harvested temperate species that have large movement patterns remains poorly tested. We measured the distribution and abundance of red king Paralithodes camtschaticus and Tanner Chionoecetes bairdi crabs inside and outside of MPAs in Glacier Bay National Park, Alaska, USA. By tagging a sub-sample of crabs with sonic tags, we estimated the movement of adult crabs from one of the MPAs (Muir Inlet) into the central portion of Glacier Bay where fishing still occurs. Tanner crabs and red king crabs moved similar average distances per day, although Tanner crabs had a higher transfer out of the Muir Inlet MPA into the central bay. Tanner crab movements were characterized by large variation among individual crabs, both in distance and direction traveled, while red king crabs migrated seasonally between 2 specific areas. Although Tanner crabs exhibited relatively large movements, distribution and abundance data suggest that they may be restricted at large spatial scales by habitat barriers. MPAs that are effective at protecting king and especially Tanner crab brood stock from fishing mortality will likely need to be larger than is typical of MPAs worldwide. However, by incorporating information on the seasonal movements of red king crabs and the location of habitat barriers for Tanner crabs, MPAs could likely be designed that would effectively protect adults from fishing mortality. ?? Inter-Research 2008.

  17. Montage, Militancy, Metaphysics: Chris Marker and André Bazin

    Directory of Open Access Journals (Sweden)

    Sarah Cooper

    2010-01-01

    Full Text Available

     

    Abstract (E: This article focuses on the relationship between the work of André Bazin and Chris Marker from the late 1940s through to the late 1950s and beyond. The division between Bazin's ŘRight Bankř affiliation with Les Cahiers du Cinéma on the one hand, and Markerřs ŘLeft Bankř allegiances on the other, is called into question here as my argument seeks to muddy the waters of their conventional ideological separation across the river Seine. Working alliteratively through Markerřs well-known talent for deft montage along with his militancy, I consider Bazinřs praise for Markerřs editing technique Ŕ in spite of famously expressing a preference elsewhere for the long take, and deep focus cinematography Ŕ and I address their political differences and convergences. Yet I also explore the rather more unexpected question of metaphysics in order to further emphasize a closer relationship between these two figures. I chart the emergence of an enduring spiritual bond between critic and filmmaker that surfaces first in Markerřs writings for the left-wing Catholic journal L’EspritLoss-of-function mutations of SURF-1 are specifically associated with Leigh syndrome with cytochrome c oxidase deficiency.

    Science.gov (United States)

    Tiranti, V; Jaksch, M; Hofmann, S; Galimberti, C; Hoertnagel, K; Lulli, L; Freisinger, P; Bindoff, L; Gerbitz, K D; Comi, G P; Uziel, G; Zeviani, M; Meitinger, T

    1999-08-01

    Mutations of SURF-1, a gene located on chromosome 9q34, have recently been identified in patients affected by Leigh syndrome (LS), associated with deficiency of cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain. To investigate to what extent SURF-1 is responsible for human disorders because of COX deficiency, we undertook sequence analysis of the SURF-1 gene in 46 unrelated patients. We analyzed 24 COX-defective patients classified as having typical Leigh syndrome (LS(COX)), 6 patients classified as Leigh-like (LL(COX)) cases, and 16 patients classified as non-LS(COX) cases. Frameshift, stop, and splice mutations of SURF-1 were detected in 18 of 24 (75%) of the LS(COX) cases. No mutations were found in the LL(COX) and non-LS(COX) group of patients. Rescue of the COX phenotype was observed in transfected cells from patients harboring SURF-1 mutations, but not in transfected cell lines from 2 patients in whom no mutations were detected by sequence analysis. Loss of function of SURF-1 protein is specifically associated with LS(COX), although a proportion of LS(COX) cases must be the result of abnormalities in genes other than SURF-1. SURF-1 is the first nuclear gene to be consistently mutated in a major category of respiratory chain defects. DNA analysis can now be used to accurately diagnose LS(COX), a common subtype of Leigh syndrome.

  18. Respiratory chain complex I deficiency due to NDUFA12 mutations as a new cause of Leigh syndrome

    DEFF Research Database (Denmark)

    Ostergaard, Elsebet; Rodenburg, Richard J; van den Brand, Mariël;

    2011-01-01

    This study investigated a girl with Leigh syndrome born to first-cousin parents of Pakistani descent with an isolated respiratory chain complex I deficiency in muscle and fibroblasts. Her early development was delayed, and from age 2 years she started losing motor abilities. Cerebral MRI showed...

  19. Mutations of human NARS2, encoding the mitochondrial asparaginyl-tRNA synthetase, cause nonsyndromic deafness and Leigh syndrome.

    Directory of Open Access Journals (Sweden)

    Mariella Simon

    2015-03-01

    Full Text Available Here we demonstrate association of variants in the mitochondrial asparaginyl-tRNA synthetase NARS2 with human hearing loss and Leigh syndrome. A homozygous missense mutation ([c.637G>T; p.Val213Phe] is the underlying cause of nonsyndromic hearing loss (DFNB94 and compound heterozygous mutations ([c.969T>A; p.Tyr323*] + [c.1142A>G; p.Asn381Ser] result in mitochondrial respiratory chain deficiency and Leigh syndrome, which is a neurodegenerative disease characterized by symmetric, bilateral lesions in the basal ganglia, thalamus, and brain stem. The severity of the genetic lesions and their effects on NARS2 protein structure cosegregate with the phenotype. A hypothetical truncated NARS2 protein, secondary to the Leigh syndrome mutation p.Tyr323* is not detectable and p.Asn381Ser further decreases NARS2 protein levels in patient fibroblasts. p.Asn381Ser also disrupts dimerization of NARS2, while the hearing loss p.Val213Phe variant has no effect on NARS2 oligomerization. Additionally we demonstrate decreased steady-state levels of mt-tRNAAsn in fibroblasts from the Leigh syndrome patients. In these cells we show that a decrease in oxygen consumption rates (OCR and electron transport chain (ETC activity can be rescued by overexpression of wild type NARS2. However, overexpression of the hearing loss associated p.Val213Phe mutant protein in these fibroblasts cannot complement the OCR and ETC defects. Our findings establish lesions in NARS2 as a new cause for nonsyndromic hearing loss and Leigh syndrome.

  1. 施耐德电气任命Chris Leong为首席营销官

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    2015年3月18日,Chris Leong被任命为首席营销官和施耐德电气的执行委员会成员。她取代了即将离开公司寻求自己职业生涯的Chris Hummel。作为首席营销官,Chris Leong将负责公司的品牌和营销战略,使施耐德电气成为客户心中最佳的一流公司。她将通过数字化客户体验的外部和内部沟通到内容与现场营销负责全球营销团队。

  2. Leigh's Disease

    Science.gov (United States)

    ... Related Dementias Bioengineering Epilepsy Health Disparities Neural Interfaces Parkinson's Disease Spinal Cord Injury Stem Cells Traumatic Brain Injury Trans-Agency Activities Interagency Research ...

  3. AFSC/RACE/SAP/Foy: Effects of ocean acidification on embryo stages of Tanner crab: Kodiak Island, Alaska.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — To study the effects of ocean acidification we examined the effects of ocean acidification on the embryo stages of the economically important southern Tanner crab,...

  4. Spatial distribution of juvenile and adult female Tanner crabs (Chionoecetes bairdi) in a glacial fjord ecosystem: Implications for recruitment processes

    Science.gov (United States)

    Nielsen, J.K.; Taggart, S.J.; Shirley, T.C.; Mondragon, J.

    2007-01-01

    A systematic pot survey in Glacier Bay, Alaska, was conducted to characterize the spatial distribution of juvenile and adult female Tanner crabs, and their association with depth and temperature. The information was used to infer important recruitment processes for Tanner crabs in glaciated ecosystems. High-catch areas for juvenile and adult female Tanner crabs were identified using local autocorrelation statistics. Spatial segregation by size class corresponded to features in the glacial landscape: high-catch areas for juveniles were located at the distal ends of two narrow glacial fjords, and high-catch areas for adults were located in the open waters of the central Bay. Juvenile female Tanner crabs were found at nearly all sampled depths (15-439 m) and temperatures (4-8??C), but the biggest catches were at depths crabs. ?? 2007 International Council for the Exploration of the Sea. Published by Oxford Journals. All rights reserved.

  5. Chiral primaries in the Leigh-Strassler deformed N=4 SYM -- a perturbative study

    CERN Document Server

    Madhu, K; Madhu, Kallingalthodi; Govindarajan, Suresh

    2007-01-01

    We look for chiral primaries in the general Leigh-Strassler deformed N=4 super Yang-Mills theory by systematically computing the planar one-loop anomalous dimension for single trace operators up to dimension six. The operators are organised into representations of the trihedral group, \\Delta(27), which is a symmetry of the Lagrangian. We find an interesting relationship between the U(1)_R-charge of chiral primaries and the representation of \\Delta(27) to which the operator belongs. Up to scaling dimension \\Delta_0=6 (and conjecturally to all dimensions) the following holds: The planar one-loop anomalous dimension vanishes only for operators that are in the singlet or three dimensional representations of \\Delta(27). For other operators, the vanishing of the one-loop anomalous dimension occurs only in a sub-locus in the space of couplings.

  6. The genetics of Leigh syndrome and its implications for clinical practice and risk management.

    Science.gov (United States)

    Ruhoy, Ilene S; Saneto, Russell P

    2014-01-01

    Leigh syndrome, also referred to as subacute necrotizing encephalomyelopathy, is a severe, early-onset neurodegenerative disorder that is relentlessly progressive and devastating to both the patient and the patient's family. Attributed to the ultimate failure of the mitochondrial respiratory chain, once it starts, the disease often results in the regression of both mental and motor skills, leading to disability and rapid progression to death. It is a mitochondrial disorder with both phenotypic and genetic heterogeneity. The cause of death is most often respiratory failure, but there are a whole host of complications, including refractory seizures, that may further complicate morbidity and mortality. The symptoms may develop slowly or with rapid progression, usually associated with age of onset. Although the disease is usually diagnosed within the first year of life, it is important to note that recent studies reveal phenotypic heterogeneity, with some patients having evidence of in utero presentation and others having adult-onset symptoms.

  7. A rapid screening with direct sequencing from blood samples for the diagnosis of Leigh syndrome

    Directory of Open Access Journals (Sweden)

    Hiroko Shimbo

    2014-01-01

    Full Text Available Large numbers of genes are responsible for Leigh syndrome (LS, making genetic confirmation of LS difficult. We screened our patients with LS using a limited set of 21 primers encompassing the frequently reported gene for the respiratory chain complexes I (ND1–ND6, and ND4L, IV(SURF1, and V(ATP6 and the pyruvate dehydrogenase E1α-subunit. Of 18 LS patients, we identified mutations in 11 patients, including 7 in mDNA (two with ATP6, 4 in nuclear (three with SURF1. Overall, we identified mutations in 61% of LS patients (11/18 individuals in this cohort. Sanger sequencing with our limited set of primers allowed us a rapid genetic confirmation of more than half of the LS patients and it appears to be efficient as a primary genetic screening in this cohort.

  8. The Coulomb branch of the Leigh-Strassler deformation and matrix models

    CERN Document Server

    Benini, F

    2004-01-01

    The Dijkgraaf-Vafa approach is used in order to study the Coulomb branch of the Leigh-Strassler massive deformation of N=4 SYM with gauge group U(N). The theory has N=1 SUSY and an N-dimensional Coulomb branch of vacua, which can be described by a family of ``generalized'' Seiberg-Witten curves. The matrix model analysis is performed by adding a tree level potential that selects particular vacua. The family of curves is found: it consists of order N branched coverings of a base torus, and it is described by multi-valued functions on the latter. The relation between the potential and the vacuum is made explicit. The gauge group SU(N) is also considered. Finally the resolvents from which expectation values of chiral operators can be extracted are presented.

  9. A note on perturbative aspects of Leigh-Strassler deformed N=4 SYM theory

    CERN Document Server

    Madhu, Kallingalthodi

    2007-01-01

    We carry out a perturbative study of the Leigh-Strassler deformed N=4 SYM theory in order to verify that the trihedral Delta(27) symmetry holds in the quantum theory. We show that the Delta(27) symmetry is preserved to two loops (at finite N) by explicitly computing the superpotential. The perturbative superpotential is not holomorphic in the couplings due to finite contributions. However, there exist coupling constant redefinitions that restore holomorphy. Interestingly, the same redefinitions appear (in the work of Jack, Jones and North[hep-ph/9603386]) if one requires the three-loop anomalous dimension to vanish in a theory where the one-loop anomalous dimension vanishes. However, the two field redefinitions seem to differ by a factor of two.

  10. ERGO Jazz Session võõrustab Chris Gall Triot. Vennad Urbid ajakohaste lauludega

    Index Scriptorium Estoniae

    2008-01-01

    14. septembril alustab Jazzkaar koostöös ERGO Kindlustusega uut sarja ERGO Jazz Session, mille avaesinejaks on Chris Gall Trio (kontserdid 14. sept.Kumu auditooriumis ja 15. sept. Tartus Athena keskuses). Vendade Urbide kontserdist "Aeg" 13. sept. Vanemuise kontserdimajas

  11. ERGO Jazz Session võõrustab Chris Gall Triot. Vennad Urbid ajakohaste lauludega

    Index Scriptorium Estoniae

    2008-01-01

    14. septembril alustab Jazzkaar koostöös ERGO Kindlustusega uut sarja ERGO Jazz Session, mille avaesinejaks on Chris Gall Trio (kontserdid 14. sept.Kumu auditooriumis ja 15. sept. Tartus Athena keskuses). Vendade Urbide kontserdist "Aeg" 13. sept. Vanemuise kontserdimajas

  12. Mutation of Mitochondrial DNA G13513A Presenting with Leigh Syndrome, Wolff-Parkinson-White Syndrome and Cardiomyopathy

    Directory of Open Access Journals (Sweden)

    Shi-Bing Wang

    2008-08-01

    Full Text Available Mutation of mitochondrial DNA (mtDNA G13513A, encoding the ND5 subunit of respiratory chain complex I, can cause mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS and Leigh syndrome. Wolff-Parkinson-White (WPW syndrome and optic atrophy were reported in a high proportion of patients with this mutation. We report an 18-month-old girl, with an 11-month history of psychomotor regression who was diagnosed with WPW syndrome and hypertrophic cardiomyopathy, in association with Leigh syndrome. Supplementation with coenzyme Q10, thiamine and carnitine prevented further regression in gross motor function but the patient's heart function deteriorated and dilated cardiomyopathy developed 11 months later. She was found to have a mutation of mtDNA G13513A. We suggest that mtDNA G13513A mutation is an important factor in patients with Leigh syndrome associated with WPW syndrome and/or optic atrophy, and serial heart function monitoring by echocardiography is recommended in this group of patients.

  13. Ocean Acidification Affects Hemocyte Physiology in the Tanner Crab (Chionoecetes bairdi)

    Science.gov (United States)

    Meseck, Shannon L.; Alix, Jennifer H.; Swiney, Katherine M.; Long, W. Christopher; Wikfors, Gary H.; Foy, Robert J.

    2016-01-01

    We used flow cytometry to determine if there would be a difference in hematology, selected immune functions, and hemocyte pH (pHi), under two different, future ocean acidification scenarios (pH = 7.50, 7.80) compared to current conditions (pH = 8.09) for Chionoecetes bairdi, Tanner crab. Hemocytes were analyzed after adult Tanner crabs were held for two years under continuous exposure to acidified ocean water. Total counts of hemocytes did not vary among control and experimental treatments; however, there were significantly greater number of dead, circulating hemocytes in crabs held at the lowest pH treatment. Phagocytosis of fluorescent microbeads by hemocytes was greatest at the lowest pH treatment. These results suggest that hemocytes were dying, likely by apoptosis, at a rate faster than upregulated phagocytosis was able to remove moribund cells from circulation at the lowest pH. Crab hemolymph pH (pHe) averaged 8.09 and did not vary among pH treatments. There was no significant difference in internal pH (pHi) within hyalinocytes among pH treatments and the mean pHi (7.26) was lower than the mean pHe. In contrast, there were significant differences among treatments in pHi of the semi-granular+granular cells. Control crabs had the highest mean semi-granular+granular pHi compared to the lowest pH treatment. As physiological hemocyte functions changed from ambient conditions, interactions with the number of eggs in the second clutch, percentage of viable eggs, and calcium concentration in the adult crab shell was observed. This suggested that the energetic costs of responding to ocean acidification and maintaining defense mechanisms in Tanner crab may divert energy from other physiological processes, such as reproduction. PMID:26859148

  14. The genetics of Leigh syndrome and its implications for clinical practice and risk management

    Directory of Open Access Journals (Sweden)

    Ruhoy IS

    2014-11-01

    Full Text Available Ilene S Ruhoy, Russell P Saneto Division of Pediatric Neurology, Seattle Children's Hospital/University of Washington, Seattle, WA, USAAbstract: Leigh syndrome, also referred to as subacute necrotizing encephalomyelopathy, is a severe, early-onset neurodegenerative disorder that is relentlessly progressive and devastating to both the patient and the patient's family. Attributed to the ultimate failure of the mitochondrial respiratory chain, once it starts, the disease often results in the regression of both mental and motor skills, leading to disability and rapid progression to death. It is a mitochondrial disorder with both phenotypic and genetic heterogeneity. The cause of death is most often respiratory failure, but there are a whole host of complications, including refractory seizures, that may further complicate morbidity and mortality. The symptoms may develop slowly or with rapid progression, usually associated with age of onset. Although the disease is usually diagnosed within the first year of life, it is important to note that recent studies reveal phenotypic heterogeneity, with some patients having evidence of in utero presentation and others having adult-onset symptoms.Keywords: mitochondrial disorder, neurodegeneration, multisystemic disease, oxidative phosphorylation, mitochondrial DNA, neuroimaging, seizures

  15. Mutations of SURF-1 in Leigh disease associated with cytochrome c oxidase deficiency.

    Science.gov (United States)

    Tiranti, V; Hoertnagel, K; Carrozzo, R; Galimberti, C; Munaro, M; Granatiero, M; Zelante, L; Gasparini, P; Marzella, R; Rocchi, M; Bayona-Bafaluy, M P; Enriquez, J A; Uziel, G; Bertini, E; Dionisi-Vici, C; Franco, B; Meitinger, T; Zeviani, M

    1998-12-01

    Leigh disease associated with cytochrome c oxidase deficiency (LD[COX-]) is one of the most common disorders of the mitochondrial respiratory chain, in infancy and childhood. No mutations in any of the genes encoding the COX-protein subunits have been identified in LD(COX-) patients. Using complementation assays based on the fusion of LD(COX-) cell lines with several rodent/human rho0 hybrids, we demonstrated that the COX phenotype was rescued by the presence of a normal human chromosome 9. Linkage analysis restricted the disease locus to the subtelomeric region of chromosome 9q, within the 7-cM interval between markers D9S1847 and D9S1826. Candidate genes within this region include SURF-1, the yeast homologue (SHY-1) of which encodes a mitochondrial protein necessary for the maintenance of COX activity and respiration. Sequence analysis of SURF-1 revealed mutations in numerous DNA samples from LD(COX-) patients, indicating that this gene is responsible for the major complementation group in this important mitochondrial disorder.

  16. Mutations in the SURF1 gene associated with Leigh syndrome and cytochrome C oxidase deficiency.

    Science.gov (United States)

    Péquignot, M O; Dey, R; Zeviani, M; Tiranti, V; Godinot, C; Poyau, A; Sue, C; Di Mauro, S; Abitbol, M; Marsac, C

    2001-05-01

    Cytochrome c oxidase (COX) deficiency is one of the major causes of Leigh Syndrome (LS), a fatal encephalopathy of infancy or childhood, characterized by symmetrical lesions in the basal ganglia and brainstem. Mutations in the nuclear genes encoding COX subunits have not been found in patients with LS and COX deficiency, but mutations have been identified in SURF1. SURF1 encodes a factor involved in COX biogenesis. To date, 30 different mutations have been reported in 40 unrelated patients. We aim to provide an overview of all known mutations in SURF1, and to propose a common nomenclature. Twelve of the mutations were insertion/deletion mutations in exons 1, 4, 6, 8, and 9; 10 were missense/nonsense mutations in exons 2, 4, 5, 7, and 8; and eight were detected at splicing sites in introns 3 to 7. The most frequent mutation was 312_321del 311_312insAT which was found in 12 patients out of 40. Twenty mutations have been described only once. We also list all polymorphisms discovered to date.

  17. Mitochondrial DNA deletion in a patient with combined features of Leigh and Pearson syndromes

    Energy Technology Data Exchange (ETDEWEB)

    Blok, R.B.; Thorburn, D.R.; Danks, D.M. [Royal Children`s Hospital, Melbourne (Australia)] [and others

    1994-09-01

    We describe a heteroplasmic 4237 bp mitochondrial DNA (mtDNA) deletion in an 11 year old girl who has suffered from progressive illness since birth. She has some features of Leigh syndrome (global developmental delay with regression, brainstem dysfunction and lactic acidosis), together with other features suggestive of Pearson syndrome (history of pancytopenia and failure to thrive). The deletion was present at a level greater than 50% in skeletal muscle, but barely detectable in skin fibroblasts following Southern blot analysis, and only observed in blood following PCR analysis. The deletion spanned nt 9498 to nt 13734, and was flanked by a 12 bp direct repeat. Genes for cytochrome c oxidase subunit III, NADH dehydrogenase subunits 3, 4L, 4 and 5, and tRNAs for glycine, arginine, histidine, serine({sup AGY}) and leucine({sup CUN}) were deleted. Southern blotting also revealed an altered Apa I restriction site which was shown by sequence analysis to be caused by G{r_arrow}A nucleotide substitution at nt 1462 in the 12S rRNA gene. This was presumed to be a polymorphism. No abnormalities of mitochondrial ultrastructure, distribution or of respiratory chain enzyme complexes I-IV in skeletal muscle were observed. Mitochondrial disorders with clinical features overlapping more than one syndrome have been reported previously. This case further demonstrates the difficulty in correlating observed clinical features with a specific mitochondrial DNA mutation.

  18. Fine Resolution Air Quality Monitoring from a Small Satellite: CHRIS/PROBA

    Directory of Open Access Journals (Sweden)

    Man Sing Wong

    2008-11-01

    Full Text Available Current remote sensing techniques fail to address the task of air quality monitoring over complex regions where multiple pollution sources produce high spatial variability. This is due to a lack of suitable satellite-sensor combinations and appropriate aerosol optical thickness (AOT retrieval algorithms. The new generation of small satellites, with their lower costs and greater flexibility has the potential to address this problem, with customised platform-sensor combinations dedicated to monitoring single complex regions or mega-cities. This paper demonstrates the ability of the European Space Agency’s small satellite sensor CHRIS/PROBA to provide reliable AOT estimates at a spatially detailed level over Hong Kong, using a modified version of the dense dark vegetation (DDV algorithm devised for MODIS. Since CHRIS has no middle-IR band such as the MODIS 2,100 nm band which is transparent to fine aerosols, the longest waveband of CHRIS, the 1,019 nm band was used to approximate surface reflectance, by the subtraction of an offset derived from synchronous field reflectance spectra. Aerosol reflectance in the blue and red bands was then obtained from the strong empirical relationship observed between the CHRIS 1,019 nm, and the blue and red bands respectively. AOT retrievals for three different dates were shown to be reliable, when compared with AERONET and Microtops II sunphotometers, and a Lidar, as well as air quality data at ground stations. The AOT images exhibited considerable spatial variability over the 11 x 11km image area and were able to indicate both local and long distance sources.

  19. Eliminating Trapping Sets in Low-Density Parity Check Codes by using Tanner Graph Covers

    CERN Document Server

    Vasic, Milos Ivkovic Shashi Kiran Chilappagari Bane

    2008-01-01

    We discuss error floor asympotics and present a method for improving the performance of low-density parity check (LDPC) codes in the high SNR (error floor) region. The method is based on Tanner graph covers that do not have trapping sets from the original code. The advantages of the method are that it is universal, as it can be applied to any LDPC code/channel/decoding algorithm and it improves performance at the expense of increasing the code length, without losing the code regularity, without changing the decoding algorithm, and, under certain conditions, without lowering the code rate. The proposed method can be modified to construct convolutional LDPC codes also. The method is illustrated by modifying Tanner, MacKay and Margulis codes to improve performance on the binary symmetric channel (BSC) under the Gallager B decoding algorithm. Decoding results on AWGN channel are also presented to illustrate that optimizing codes for one channel/decoding algorithm can lead to performance improvement on other chann...

  20. Skeletal age estimation in a contemporary Western Australian population using the Tanner-Whitehouse method.

    Science.gov (United States)

    Maggio, Ariane; Flavel, Ambika; Hart, Rob; Franklin, Daniel

    2016-06-01

    Various age estimation techniques have been utilised in Australia to evaluate the age of individuals who do not have documentation to determine legal majority/culpability. These age estimation techniques rely on the assessment of skeletal development as visualised in radiographs, CT scans, MRI or ultrasound modalities, and subsequent comparison to reference standards. These standards are not always population specific and are thus known to be less accurate when applied outside of the original reference sample, leading to potential ethical implications. Therefore, the present study aims to: (i) explore the variation in developmental trajectories between the established Tanner-Whitehouse (TW) age estimation standards and a Western Australian population; and (ii) develop specific hand-wrist age estimation standards for the latter population. The present study examines digital anterior-posterior hand-wrist radiographs of 360 individuals 0 to 24.9 years of age, equally represented by sex. Each radiograph was assessed using the RUS, Carpal and 20-bone methods of Tanner et al. The standard error of the estimate (SEE) was calculated for each method (range: ♀ SEE ±0.4-11.5 years; ♂ SEE ±0.9-10.1 years). The most accurate method was TW3 RUS for females and the TW2 Carpal system for males. The 50th centile skeletal maturity scores for each year age group were plotted against average chronological age to produce polynomial regression standards with a demonstrated accuracy of (♀ SEE ±0.09-3.46 years; ♂ SEE ±0.02-3.42 years) for females and males, respectively. The standards presented here can be used in future forensic investigations that require age estimation of hand-wrist bones in a Western Australian population, however, they are not appropriate for establishing age of majority (18 years), as skeletal maturity was attained on average earlier than 15 years of age in both sexes for all three systems examined. Copyright © 2016 Elsevier Ireland Ltd. All rights

  1. Abordagem anestésica em paciente pediátrico com síndrome de Leigh Abordaje anestésico en paciente Pediátrico con el síndrome de Leigh Anesthetic management of a pediatric patient with Leigh syndrome

    OpenAIRE

    Ismail Serhat Kocamanoglu; Esra Sarihasan

    2013-01-01

    JUSTIFICATIVA E OBJETIVOS: A síndrome de Leigh (SL) é uma doença rara causada por anomalias na produção de energia mitocondrial. O sistema nervoso central é afetado com mais frequência, com retardo psicomotor, convulsões, nistagmo, oftalmoparesia, atrofia óptica, ataxia, distonia ou insuficiência respiratória. Os procedimentos cirúrgicos e anestésicos provocam irritabilidade traqueal e podem exacerbar os riscos de aspiração, sibilação, dificuldade respiratória, respiração ofegante, hipoventil...

  2. Chris Maoca:耐力持久才能让你挨过终点

    Institute of Scientific and Technical Information of China (English)

    荀尚香

    2012-01-01

    日前,世界铁人三项比赛多冠王、世界纪录保持者Chris Maoca来到中国上海.参加其代言的Under Armour品牌的、商业活动。在与本刊对话中,被美国爱好者程以爱称Macca的铁三体能王,坦诚道出耐力训练的“三驾马车”。

  3. Effect of the aerosol type uncertainty on the surface reflectance retrieval using CHRIS/PROBA hyperspectral images over land.

    Science.gov (United States)

    Tirelli, C.; Manzo, C.; Curci, G.; Bassani, C.

    2014-12-01

    The surface reflectance is crucial for the quantitative analysis of land surface properties in geological, agricultural and urban studies. The first requirement for a reliable surface reflectance estimation is an accurate atmospheric correction obtained by an appropriate selection of aerosol loading and type. The aerosol optical thickness at 550nm is widely used to describe the aerosol loading. Recent works have highlighted the relevant role of the aerosol types on the atmospheric correction process defined by their micro-physical properties. The aim of this work is to evaluate the radiative impact of the aerosol type on the surface reflectance obtained from CHRIS (Compact High Resolution Imaging Spectrometer) hyperspectral data over land. CHRIS on PROBA satellite is an high resolution multi-angular imaging spectrometer, operating in the visible near-infrared spectral domain (400 to 1000 nm). As test case the urban site of Brussels has been selected. The physically-based algorithm CHRIS@CRI (CHRIS Atmospherically Corrected Reflectance Imagery) has been developed specifically for CHRIS data by using the vector version of 6S (6SV) radiative transfer model. The atmospheric data needed for the atmospheric correction were obtained from CIMEL CE-318 of the Brussels AERONET station. CHRIS images were selected if simultaneous AERONET data were available. Other specific requirements for imagery acquisition were high aerosol loading and high solar irradiation. The aerosol radiative impact has been investigated comparing the reflectance obtained by applying the CHRIS@CRI algorithm with different aerosol types: the three aerosol standard of 6SV and two characterized by specific microphysical properties provided by the AERONET station and calculated with FlexAOD code (a post-processing tool of the chemical transport model GEOS-Chem), respectively. The results show a clear dependence of the atmospheric correction results on the aerosol absorption properties.

  4. The mitochondrial DNA 10197 G > A mutation causes MELAS/Leigh overlap syndrome presenting with acute auditory agnosia.

    Science.gov (United States)

    Leng, Yinglin; Liu, Yuhe; Fang, Xiaojing; Li, Yao; Yu, Lei; Yuan, Yun; Wang, Zhaoxia

    2015-04-01

    Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes/Leigh (MELAS/LS) overlap syndrome is a mitochondrial disorder subtype with clinical and magnetic resonance imaging (MRI) features that are characteristic of both MELAS and Leigh syndrome (LS). Here, we report an MELAS/LS case presenting with cortical deafness and seizures. Cranial MRI revealed multiple lesions involving bilateral temporal lobes, the basal ganglia and the brainstem, which conformed to neuroimaging features of both MELAS and LS. Whole mitochondrial DNA (mtDNA) sequencing and PCR-RFLP revealed a de novo heteroplasmic m.10197 G > A mutation in the NADH dehydrogenase subunit 3 gene (ND3), which was predicted to cause an alanine to threonine substitution at amino acid 47. Although the mtDNA m.10197 G > A mutation has been reported in association with LS, Leber hereditary optic neuropathy and dystonia, it has never been linked with MELAS/LS overlap syndrome. Our patient therefore expands the phenotypic spectrum of the mtDNA m.10197 G > A mutation.

  5. Free-thiamine is a potential biomarker of thiamine transporter-2 deficiency: a treatable cause of Leigh syndrome.

    Science.gov (United States)

    Ortigoza-Escobar, Juan Darío; Molero-Luis, Marta; Arias, Angela; Oyarzabal, Alfonso; Darín, Niklas; Serrano, Mercedes; Garcia-Cazorla, Angels; Tondo, Mireia; Hernández, María; Garcia-Villoria, Judit; Casado, Mercedes; Gort, Laura; Mayr, Johannes A; Rodríguez-Pombo, Pilar; Ribes, Antonia; Artuch, Rafael; Pérez-Dueñas, Belén

    2016-01-01

    Thiamine transporter-2 deficiency is caused by mutations in the SLC19A3 gene. As opposed to other causes of Leigh syndrome, early administration of thiamine and biotin has a dramatic and immediate clinical effect. New biochemical markers are needed to aid in early diagnosis and timely therapeutic intervention. Thiamine derivatives were analysed by high performance liquid chromatography in 106 whole blood and 38 cerebrospinal fluid samples from paediatric controls, 16 cerebrospinal fluid samples from patients with Leigh syndrome, six of whom harboured mutations in the SLC19A3 gene, and 49 patients with other neurological disorders. Free-thiamine was remarkably reduced in the cerebrospinal fluid of five SLC19A3 patients before treatment. In contrast, free-thiamine was slightly decreased in 15.2% of patients with other neurological conditions, and above the reference range in one SLC19A3 patient on thiamine supplementation. We also observed a severe deficiency of free-thiamine and low levels of thiamine diphosphate in fibroblasts from SLC19A3 patients. Surprisingly, pyruvate dehydrogenase activity and mitochondrial substrate oxidation rates were within the control range. Thiamine derivatives normalized after the addition of thiamine to the culture medium. In conclusion, we found a profound deficiency of free-thiamine in the CSF and fibroblasts of patients with thiamine transporter-2 deficiency. Thiamine supplementation led to clinical improvement in patients early treated and restored thiamine values in fibroblasts and cerebrospinal fluid.

  6. L’oeuvre au miroir. Une journée d’Andrei Arsenevitch, Chris Marker

    Directory of Open Access Journals (Sweden)

    Luc Vancheri

    2009-10-01

    Full Text Available Abstract (E: Chris Marker films the last moments of Andrei Tarkovski’s life for the collection
    Cinéma, de notre temps. Une jounée d’Andrei Arsenevitch is neither a portrait nor a visual study, but
    rather a work of mirroring and reflection. The film is profoundly amicable. It shows, through a series
    of poetic figures, the strange bonds between man and his images. They do not look like him, but
    instead are implicit resemblances, correlating fiction and life, forms of idleness that feed all genuine
    inspiration.
    Abstract (F: C’est pour la collection Cinéma, de notre temps, que Chris Marker filme les derniers
    moments de la vie d’Andrei Tarkovski. Ni portrait ni étude visuelle, Une journée d’Andrei Arsenevitch
    est plus sûrement une oeuvre en miroir, profondément amicale, qui compose selon une série de figures
    poétiques l’étrange relation qui relie un homme à ses images. Elles ne lui ressemblent pas, elles font
    de l’implicite ressemblance qui met en contact la fiction et la vie, la forme d’un désoeuvrement qui
    nourrit toute inspiration véritable.

  7. The mitochondrial 13513G > A mutation is most frequent in Leigh syndrome combined with reduced complex I activity, optic atrophy and/or Wolff-Parkinson-White.

    NARCIS (Netherlands)

    Ruiter, E.M.; Siers, M.H.; Elzen, C. van der; Engelen, B.G.M. van; Smeitink, J.A.M.; Rodenburg, R.J.T.; Hol, F.A.

    2007-01-01

    The m.13513G > A transition in the mitochondrial gene encoding the ND5 subunit of respiratory chain complex I, can cause mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) and has been reported to be a frequent cause of Leigh syndrome (LS). We determined the fre

  8. The mitochondrial 13513G > A mutation is most frequent in Leigh syndrome combined with reduced complex I activity, optic atrophy and/or Wolff-Parkinson-White.

    NARCIS (Netherlands)

    Ruiter, E.M.; Siers, M.H.; Elzen, C. van der; Engelen, B.G.M. van; Smeitink, J.A.M.; Rodenburg, R.J.T.; Hol, F.A.

    2007-01-01

    The m.13513G > A transition in the mitochondrial gene encoding the ND5 subunit of respiratory chain complex I, can cause mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) and has been reported to be a frequent cause of Leigh syndrome (LS). We determined the fre

  9. Chris Kraus: "Polli päevikud" on minu väga isiklik lugu mu esivanematest / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2010-01-01

    Chris Kraus filmi "Polli päevikud" (Saksamaa-Austria-Eesti) saamisloost. Näitlejatest, Tambet Tuisu osatäitmisest. Film üheks peategelaseks on režissööri vanatädi, luuletaja Oda Saefer. Tegevus toimub Eestis 1914. a. Polli (Põlula) mõis ehitati filmi jaoks üles Matsiranda Varbla lähedal. PÖFF-i EurAsia programmi žürii tunnistas Chris Krausi parimaks režissööriks

  10. Chris Kraus: "Polli päevikud" on minu väga isiklik lugu mu esivanematest / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2010-01-01

    Chris Kraus filmi "Polli päevikud" (Saksamaa-Austria-Eesti) saamisloost. Näitlejatest, Tambet Tuisu osatäitmisest. Film üheks peategelaseks on režissööri vanatädi, luuletaja Oda Saefer. Tegevus toimub Eestis 1914. a. Polli (Põlula) mõis ehitati filmi jaoks üles Matsiranda Varbla lähedal. PÖFF-i EurAsia programmi žürii tunnistas Chris Krausi parimaks režissööriks

  11. Peristaltic Flow of Phan-Thien-Tanner Fluid in an Asymmetric Channel with Porous Medium

    Directory of Open Access Journals (Sweden)

    Kuppalapalle Vajravelu

    2016-01-01

    Full Text Available This paper deals with peristaltic transport of Phan-Thien-Tanner fluid in an asymmetric channel induced by sinusoidal peristaltic waves traveling down the flexible walls of the channel. The flow is investigated in a wave frame of reference moving with the velocity of the waveby using the long wavelength and low Reynolds number approximations.The nonlinear governing equations are solved employing a perturbation method by choosing as the perturbation parameter. The expressions for velocity, stream function and pressure gradient are obtained. The features of the flow characteristics are analyzed through graphs and the obtained results are discussed in detail. It is noticed that the peristaltic pumping gets reduced due to an increase in the phase difference of the traveling waves. It is also observed that the size of the trapping bolus is a decreasing function of the permeability parameter and the Weissenberg number. Furthermore, the results obtained for the flow characteristics reveal many interesting behaviors that warrant further study on the non-Newtonian fluid phenomena, especially the Peristaltic flow phenomena.

  12. Stability and Hopf Bifurcation in a Modified Holling-Tanner Predator-Prey System with Multiple Delays

    Directory of Open Access Journals (Sweden)

    Zizhen Zhang

    2012-01-01

    Full Text Available A modified Holling-Tanner predator-prey system with multiple delays is investigated. By analyzing the associated characteristic equation, the local stability and the existence of periodic solutions via Hopf bifurcation with respect to both delays are established. Direction and stability of the periodic solutions are obtained by using normal form and center manifold theory. Finally, numerical simulations are carried out to substantiate the analytical results.

  13. AFSC/RACE/SAP/Long: Data from: Effects of Ocean Acidification on Juvenile Red King Crab (Paralithodes camtschaticus) and Tanner Crab (Chionoecetes bairdi) Growth, Condition, Calcification, and Survival

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is the results of a laboratory experiment. Juvenile red king crab and Tanner crab were reared in individual containers for nearly 200 days in flowing...

  14. AFSC/RACE/SAP/Foy: The effects of ocean acidification on ovigerous Tanner crab size, calcium, and magnesium content. : Kodiak Island, Alaska.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — To study the effects of ocean acidification we conducted laboratory experiments with adult ovigerous females of the economically important southern Tanner crab,...

  15. AFSC/RACE/FBEP/Ryer: Depth distribution, habitat associations, and differential growth of newly settled southern Tanner crab (Chionoecetes bairdi) in embayments around Kodiak Island, Alaska

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This dataset is from field surveys that examined depth distribution, habitat association, and growth of newly settled Tanner crab at 4 sites around the eastern end...

  16. Maturity and activity-related differences in bone mineral density: Tanner I vs. II and gymnasts vs. non-gymnasts.

    Science.gov (United States)

    Dowthwaite, Jodi N; DiStefano, James G; Ploutz-Snyder, Robert J; Kanaley, Jill A; Scerpella, Tamara A

    2006-10-01

    This study tests the hypotheses that (1) Tanner I and Tanner II girls comprise distinct maturational cohorts, exhibiting BMD differences that are not explained by age and body size alone; and (2) within these distinct maturational cohorts, BMD is higher in gymnasts than non-gymnasts, independent of age and body size. Premenarcheal artistic gymnasts (n=28) and non-gymnasts (n=28) were evaluated. Fan-beam DXA measured areal BMD (aBMD) at the forearm, femoral neck, and lumbar spine; fat free mass (FFM) was derived from whole-body scans. Height, weight, physical activity and calcium intake were assessed. Group means were compared using ANOVA; ANCOVA was used to adjust for age, height and FFM. For all 3 sites and both maturity levels, gymnasts had higher aBMD than non-gymnasts, independent of age and body size (7.2-20.8%, pactivity is evident at all three sites. Trends in Tanner group differences in aBMD were specific to gymnast and non-gymnast activity groups and therefore were not generalizable to all subjects. Overall, aBMD correlations and ANCOVA results differ by activity group, maturity level and site. These results highlight the need to consider both maturity and activity status in studies assessing bone accrual.

  17. Chris Tudda, Cold War Summits: A History, from Potsdam to Malta

    OpenAIRE

    Andı, Ahmed Fatih

    2016-01-01

    Amerikalı tarihçi Chris Tudda’nın 2015’te çıkan “Cold War Summits: A History, From Potsdam to Malta” başlıklı kitabı uluslararası tarih literatürüne yeni ve nispeten farklı bir bakış sunuyor. Kitap, özellikle alışılagelmiş uluslararası tarih anlatısını farklı analiz düzeyleri arasında gidip gelen bir yaklaşımla ele almasıyla dikkat çekiyor.

  18. Information Management Systems for Monitoring and Documenting World Heritage - the Silk Roads Chris

    Science.gov (United States)

    Vileikis, O.; Serruys, E.; Dumont, B.; van Balen, K.; Santana Quinterod, M.; de Maeyer, P.; Tigny, V.

    2012-07-01

    This paper discusses the application of Information Management Systems (IMS) for documenting and monitoring World Heritage (WH) properties. The application of IMS in WH can support all stakeholders involved in conservation, and management of cultural heritage by more easily inventorying, mining and exchanging information from multiple sources based on international standards. Moreover, IMS could assist in detecting damages and preparing management strategies to mitigate risks, and slowing down the deterioration of the integrity of WH properties. The case study of the Silk Roads Cultural Heritage Resource Information System (CHRIS), a Belgian Federal Science Policy Office funded project, illustrates the capabilities of IMS in the context of the nomination of the Central Asian Silk Roads on the WH List. This multi-lingual, web-based IMS will act as a collaborative platform allowing for the completion of improved transnational nomination dossiers and subsequent monitoring activities with all necessary baseline information to easily verify consistency and quality of the proposal. The Silk Roads CHRIS Geospatial Content Management System uses open source technologies and allows to georeference data from different scales and sources including data from field recording methods and combine it with historical and heritage features documented through various means such as textual descriptions, documents, photographs, 3D models or videos. Moreover, tailored maps can also be generated by overlaying a selection of available layers and then be exported to support the nomination dossier. Finally, by using this innovative information and decision support system, the State Parties and other interested stakeholders will have access to a complete nomination dossier and could therefore respond more effectively to hazards and disaster phenomena.

  19. The Cooperative Health Research in South Tyrol (CHRIS) study: rationale, objectives, and preliminary results.

    Science.gov (United States)

    Pattaro, Cristian; Gögele, Martin; Mascalzoni, Deborah; Melotti, Roberto; Schwienbacher, Christine; De Grandi, Alessandro; Foco, Luisa; D'Elia, Yuri; Linder, Barbara; Fuchsberger, Christian; Minelli, Cosetta; Egger, Clemens; Kofink, Lisa S; Zanigni, Stefano; Schäfer, Torsten; Facheris, Maurizio F; Smárason, Sigurður V; Rossini, Alessandra; Hicks, Andrew A; Weiss, Helmuth; Pramstaller, Peter P

    2015-11-05

    The Cooperative Health Research In South Tyrol (CHRIS) study is a population-based study with a longitudinal lookout to investigate the genetic and molecular basis of age-related common chronic conditions and their interaction with life style and environment in the general population. All adults of the middle and upper Vinschgau/Val Venosta are invited, while 10,000 participants are anticipated by mid-2017. Family participation is encouraged for complete pedigree reconstruction and disease inheritance mapping. After a pilot study on the compliance with a paperless assessment mode, computer-assisted interviews have been implemented to screen for conditions of the cardiovascular, endocrine, metabolic, genitourinary, nervous, behavioral, and cognitive system. Fat intake, cardiac health, and tremor are assessed instrumentally. Nutrient intake, physical activity, and life-course smoking are measured semi-quantitatively. Participants are phenotyped for 73 blood and urine parameters and 60 aliquots per participant are biobanked (cryo-preserved urine, DNA, and whole and fractionated blood). Through liquid-chromatography mass-spectrometry analysis, metabolite profiling of the mitochondrial function is assessed. Samples are genotyped on 1 million variants with the Illumina HumanOmniExpressExome array and the first data release including 4570 fully phenotyped and genotyped samples is now available for analysis. Participants' follow-up is foreseen 6 years after the first visit. The target population is characterized by long-term social stability and homogeneous environment which should both favor the identification of enriched genetic variants. The CHRIS cohort is a valuable resource to assess the contribution of genomics, metabolomics, and environmental factors to human health and disease. It is awaited that this will result in the identification of novel molecular targets for disease prevention and treatment.

  20. Estimating forest species abundance through linear unmixing of CHRIS/PROBA imagery

    Science.gov (United States)

    Stagakis, Stavros; Vanikiotis, Theofilos; Sykioti, Olga

    2016-09-01

    The advancing technology of hyperspectral remote sensing offers the opportunity of accurate land cover characterization of complex natural environments. In this study, a linear spectral unmixing algorithm that incorporates a novel hierarchical Bayesian approach (BI-ICE) was applied on two spatially and temporally adjacent CHRIS/PROBA images over a forest in North Pindos National Park (Epirus, Greece). The scope is to investigate the potential of this algorithm to discriminate two different forest species (i.e. beech - Fagus sylvatica, pine - Pinus nigra) and produce accurate species-specific abundance maps. The unmixing results were evaluated in uniformly distributed plots across the test site using measured fractions of each species derived by very high resolution aerial orthophotos. Landsat-8 images were also used to produce a conventional discrete-type classification map of the test site. This map was used to define the exact borders of the test site and compare the thematic information of the two mapping approaches (discrete vs abundance mapping). The required ground truth information, regarding training and validation of the applied mapping methodologies, was collected during a field campaign across the study site. Abundance estimates reached very good overall accuracy (R2 = 0.98, RMSE = 0.06). The most significant source of error in our results was due to the shadowing effects that were very intense in some areas of the test site due to the low solar elevation during CHRIS acquisitions. It is also demonstrated that the two mapping approaches are in accordance across pure and dense forest areas, but the conventional classification map fails to describe the natural spatial gradients of each species and the actual species mixture across the test site. Overall, the BI-ICE algorithm presented increased potential to unmix challenging objects with high spectral similarity, such as different vegetation species, under real and not optimum acquisition conditions. Its

  1. INFORMATION MANAGEMENT SYSTEMS FOR MONITORING AND DOCUMENTING WORLD HERITAGE - THE SILK ROADS CHRIS

    Directory of Open Access Journals (Sweden)

    O. Vileikis

    2012-07-01

    Full Text Available This paper discusses the application of Information Management Systems (IMS for documenting and monitoring World Heritage (WH properties. The application of IMS in WH can support all stakeholders involved in conservation, and management of cultural heritage by more easily inventorying, mining and exchanging information from multiple sources based on international standards. Moreover, IMS could assist in detecting damages and preparing management strategies to mitigate risks, and slowing down the deterioration of the integrity of WH properties. The case study of the Silk Roads Cultural Heritage Resource Information System (CHRIS, a Belgian Federal Science Policy Office funded project, illustrates the capabilities of IMS in the context of the nomination of the Central Asian Silk Roads on the WH List. This multi-lingual, web-based IMS will act as a collaborative platform allowing for the completion of improved transnational nomination dossiers and subsequent monitoring activities with all necessary baseline information to easily verify consistency and quality of the proposal. The Silk Roads CHRIS Geospatial Content Management System uses open source technologies and allows to georeference data from different scales and sources including data from field recording methods and combine it with historical and heritage features documented through various means such as textual descriptions, documents, photographs, 3D models or videos. Moreover, tailored maps can also be generated by overlaying a selection of available layers and then be exported to support the nomination dossier. Finally, by using this innovative information and decision support system, the State Parties and other interested stakeholders will have access to a complete nomination dossier and could therefore respond more effectively to hazards and disaster phenomena.

  2. Statistical versus Musical Significance: Commentary on Leigh VanHandel's 'National Metrical Types in Nineteenth Century Art Song'

    Directory of Open Access Journals (Sweden)

    Justin London

    2010-01-01

    Full Text Available In “National Metrical Types in Nineteenth Century Art Song” Leigh Van Handel gives a sympathetic critique of William Rothstein’s claim that in western classical music of the late 18th and 19th centuries there are discernable differences in the phrasing and metrical practice of German versus French and Italian composers. This commentary (a examines just what Rothstein means in terms of his proposed metrical typology, (b questions Van Handel on how she has applied it to a purely melodic framework, (c amplifies Van Handel’s critique of Rothstein, and then (d concludes with a rumination on the reach of quantitative (i.e., statistically-driven versus qualitative claims regarding such things as “national metrical types.”

  3. Disturbed mitochondrial and peroxisomal dynamics due to loss of MFF causes Leigh-like encephalopathy, optic atrophy and peripheral neuropathy.

    Science.gov (United States)

    Koch, Johannes; Feichtinger, René G; Freisinger, Peter; Pies, Mechthild; Schrödl, Falk; Iuso, Arcangela; Sperl, Wolfgang; Mayr, Johannes A; Prokisch, Holger; Haack, Tobias B

    2016-04-01

    Mitochondria are dynamic organelles which undergo continuous fission and fusion to maintain their diverse cellular functions. Components of the fission machinery are partly shared between mitochondria and peroxisomes, and inherited defects in two such components (dynamin-related protein (DRP1) and ganglioside-induced differentiation-associated protein 1 (GDAP1)) have been associated with human disease. Deficiency of a third component (mitochondrial fission factor, MFF) was recently reported in one index patient, rendering MFF another candidate disease gene within the expanding field of mitochondrial and peroxisomal dynamics. Here we investigated three new patients from two families with pathogenic mutations in MFF. The patients underwent clinical examination, brain MRI, and biochemical, cytological and molecular analyses, including exome sequencing. The patients became symptomatic within the first year of life, exhibiting seizures, developmental delay and acquired microcephaly. Dysphagia, spasticity and optic and peripheral neuropathy developed subsequently. Brain MRI showed Leigh-like patterns with bilateral changes of the basal ganglia and subthalamic nucleus, suggestive of impaired mitochondrial energy metabolism. However, activities of mitochondrial respiratory chain complexes were found to be normal in skeletal muscle. Exome sequencing revealed three different biallelic loss-of-function variants in MFF in both index cases. Western blot studies of patient-derived fibroblasts indicated normal content of mitochondria and peroxisomes, whereas immunofluorescence staining revealed elongated mitochondria and peroxisomes. Furthermore, increased mitochondrial branching and an abnormal distribution of fission-mediating DRP1 were observed. Our findings establish MFF loss of function as a cause of disturbed mitochondrial and peroxisomal dynamics associated with early-onset Leigh-like basal ganglia disease. We suggest that, even if laboratory findings are not indicative of

  4. Daily surface water temperature data collected from bucket casts from pier at Leigh Marine Laboratory, Auckland, New Zealand from 1967-01-01 to 2011-04-30 (NCEI Accession 0127323)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Collected seawater temperatures at the Leigh Marine Laboratory. Dataset contains an archive of material to 2011. The location of the laboratory is lat: -36.26929,...

  5. A Study Of Ips Typographus Pest Infestation With The Use Of Multi-Angular CHRIS-Proba Data

    Science.gov (United States)

    Filchev, Lachezar; Panayotov, Momchil; Ling, Feilong

    2013-12-01

    Insects' infestations of coniferous forests have been in the focus of the forestry community for decades. Research that is dealing with the assessment of the impacts on forests and assessment of the area affected by the infestations has been assisted by remotely sensed data after the onset of civilian remote sensing era and making the large archives of satellite data centres of NASA, ESA, and JAXA available to the researcher's community. The present study assesses the impact from European Bark beetle (Ips typhographus L.) outbreak on Norway Spruce (Picea abies L.) forests in the UNESCO MAB reserve Bistrishko Branishte in Bulgaria using the ESA's third-party mission multiangular satellite CHRIS/PROBA Mode 1 spectroradiometer data. The study aims at assessing the impact of the infestation by comparing the pre- and post-fire CHRIS/PROBA Mode 1 narrow-band vegetation indices (VIs). In order to achieve the study objective the ‘dead spruce forest' areas were extracted using eight target detection algorithms. Statistics from the CHRIS/PROBA Mode 1 VIs was drawn and compared with one another for the two dates of acquisition. It was found that the areas affected by pest infestation can be well differentiated on CHRIS/PROBA data but the results vary due to the date of acquisition, illumination conditions, and season changes. The results from the study suggest that continuous space monitoring of insect infested coniferous forests can be successfully carried out by employing present-day available hyperspectral satellite data.

  6. Merging the Minnaert- k parameter with spectral unmixing to map forest heterogeneity with CHRIS/PROBA data

    NARCIS (Netherlands)

    Verrelst, J.; Schaepman, M.E.; Clevers, J.G.P.W.

    2010-01-01

    The Compact High Resolution Imaging Spectrometer (CHRIS) mounted onboard the Project for Onboard Autonomy (PROBA) spacecraft is capable of sampling reflected radiation at five viewing angles over the visible and near-infrared regions of the solar spectrum with high spatial resolution. We combined th

  7. A comparison of three infant skinfold reference standards: Tanner-Whitehouse, Cambridge Infant Growth Study, and WHO Child Growth Standards.

    Science.gov (United States)

    Miller, Elizabeth M

    2015-10-01

    As researchers increasingly focus on early infancy as a critical period of development, there is a greater need for methodological tools that can address all aspects of infant growth. Infant skinfold measures, in particular, are measurements in need of reliable reference standards that encompass all ages of infants and provide an accurate assessment of the relative fatness of a population. This report evaluates three published reference standards for infant skinfold measurements: Tanner-Whitehouse, Cambridge Infant Growth Study, and the World Health Organization (WHO) Child Growth Standards. To assess these standards, triceps skinfolds from a population of rural Kenyan infants (n = 250) and triceps skinfolds and subscapular skinfolds from infants in the National Health and Nutrition Examination Survey 1999-2002 (NHANES; n = 1197) were calculated as z-scores from the lambda-mu-sigma curves provided by each reference population. The Tanner-Whitehouse standards represented both the Kenyan and US populations as lean, while the Cambridge standards represented both populations as overfat. The distribution of z-scores based on the WHO standards fell in the middle, but excluded infants from both populations who were below the age of 3 months. Based on these results, the WHO reference standard is the best skinfold reference standard for infants over the age of 3 months. For populations with infants of all ages, the Tanner-Whitehouse standards are recommended, despite representing both study populations as underfat. Ideally, the WHO will extend their reference standard to include infants between the ages of 0 and 3 months.

  8. U.S. tabloid magazine coverage of a celebrity dating abuse incident: Rihanna and Chris Brown.

    Science.gov (United States)

    Rothman, Emily F; Nagaswaran, Anita; Johnson, Renee M; Adams, Kelley M; Scrivens, Juliane; Baughman, Allyson

    2012-01-01

    Dating abuse is a prevalent adolescent health problem with substantial public health consequences. As many as 1 in 10 high school students in the United States reports being "hit, slapped, or physically hurt on purpose" by his or her boyfriend or girlfriend in the past year. The authors used the Rihanna-Chris Brown dating abuse incident of 2009 as a case study to conduct what is, to our knowledge, the first assessment of media framing of dating abuse. The authors reviewed the 20 leading U.S. single-copy sales magazines published from February to April 2009 and identified 48 relevant articles, which were all printed in 7 tabloid magazines. The authors conducted a content analysis of the media frames of the articles using 5 frame categories: (a) abuse is objectionable, (b) victim-blaming, (c) abuse is sexualized/romanticized, (d) myths about abuse perpetration, and (e) abuse is normalized. Abuse is objectionable was the dominant frame of 40% of articles, victim-blaming in 36%. Although the majority of articles reviewed (83%) made at least passing reference to the idea that abuse is wrong, a minority (40%) used a dominant frame that condemned abuse. Instead, the majority of articles communicated mixed messages about dating abuse, and many minimized the seriousness of partner abuse perpetration. Advocacy is needed to improve future tabloid media framing of dating abuse incidents.

  9. The Compact High Resolution Imaging Spectrometer (CHRIS): the future of hyperspectral satellite sensors. Imagery of Oostende coastal and inland waters

    OpenAIRE

    B. De Mol; Ruddick, K

    2004-01-01

    The gap between airborne imaging spectroscopy and traditional multi spectral satellite sensors is decreasing thanks to a new generation of satellite sensors of which CHRIS mounted on the small and low-cost PROBA satellite is the prototype. Although image acquisition and analysis are still in a test phase, the high spatial and spectral resolution and pointability have proved their potential. Because of the high resolution small features, which were before only visible on airborne images, becom...

  10. SQL by Example. 2. PHP and MySQL Web Application based on Tanner-Whitehouse Standard

    Directory of Open Access Journals (Sweden)

    Sorana Daniela BOLBOACĂ

    2003-03-01

    Full Text Available In pediatrics, skeletal maturity, also called “bone age”, an expression of biological maturity of a child, is an important quantitative measure for the clinical diagnosis of endocrinological problems and growth disorders. Bone age is also used in monitoring children with hormone therapy. Skeletal maturity may be assessed by analysis of the ossification centers of the hand, foot, knee, elbow or pelvis but most often used is the hand. Skeletal maturity diagnosis is usually based on a visual comparison of a left-hand wrist radiograph with atlas patterns and the most common method used is the Tanner-Whitehouse method. With the help of PHP and MySQL a computer-assisted software we developed, based on Tanner-Whitehouse method, for bone age assessment of children and young people. The program is a client-server one and all data are saved into a database server. The program (1 display control radiographies, schematic drawings and specifications for every stage of hand bones until maturity stage, (2 allow user to select a maturity stage for every bone, (3 save and query personal data of patients, (4 save and query consultations and (5 make consultation reports. URL address: http://vl.academicdirect.ro/medical_informatics/bone_age/v1.2/

  11. Loss of the smallest subunit of cytochrome c oxidase, COX8A, causes Leigh-like syndrome and epilepsy.

    Science.gov (United States)

    Hallmann, Kerstin; Kudin, Alexei P; Zsurka, Gábor; Kornblum, Cornelia; Reimann, Jens; Stüve, Burkhard; Waltz, Stephan; Hattingen, Elke; Thiele, Holger; Nürnberg, Peter; Rüb, Cornelia; Voos, Wolfgang; Kopatz, Jens; Neumann, Harald; Kunz, Wolfram S

    2016-02-01

    Isolated cytochrome c oxidase (complex IV) deficiency is one of the most frequent respiratory chain defects in humans and is usually caused by mutations in proteins required for assembly of the complex. Mutations in nuclear-encoded structural subunits are very rare. In a patient with Leigh-like syndrome presenting with leukodystrophy and severe epilepsy, we identified a homozygous splice site mutation in COX8A, which codes for the ubiquitously expressed isoform of subunit VIII, the smallest nuclear-encoded subunit of complex IV. The mutation, affecting the last nucleotide of intron 1, leads to aberrant splicing, a frame-shift in the highly conserved exon 2, and decreased amount of the COX8A transcript. The loss of the wild-type COX8A protein severely impairs the stability of the entire cytochrome c oxidase enzyme complex and manifests in isolated complex IV deficiency in skeletal muscle and fibroblasts, similar to the frequent c.845_846delCT mutation in the assembly factor SURF1 gene. Stability and activity of complex IV could be rescued in the patient's fibroblasts by lentiviral expression of wild-type COX8A. Our findings demonstrate that COX8A is indispensable for function of human complex IV and its mutation causes human disease.

  12. Chipman Leigh, The World of Pharmacy and Pharmacists in Mamlūk Cairo, Leyde, Brill, 2009, 318 p.

    Directory of Open Access Journals (Sweden)

    Sylvie Denoix

    2011-05-01

    Full Text Available Le livre de Leigh Chipman est l’analyse d’un ouvrage de pharmacologie, le Minhâǧ al-dukkân wa dustûr al-a‘yân fî’l-a‘mâl wa’l-tarâkib al-adwiya al-nâfi‘a  li’l-insân , soit « Le protocole de l’officine et  la convention de ce qu’il y a de meilleur en ce qui concerne les préparations et les compositions des médicaments bénéfiques aux êtres humains », composé en 658h/1260 au Caire par un pharmacien juif égyptien nommé Abû-l-Munâ Dâwud b. Abî Naṣr al-Kûhîn al-‘Aṭṭâr al-Hârûnî al-Isrâ’ilî. Cet ou...

  13. Abordagem anestésica em paciente pediátrico com síndrome de Leigh

    Directory of Open Access Journals (Sweden)

    Ismail Serhat Kocamanoglu

    2013-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A síndrome de Leigh (SL é uma doença rara causada por anomalias na produção de energia mitocondrial. O sistema nervoso central é afetado com mais frequência, com retardo psicomotor, convulsões, nistagmo, oftalmoparesia, atrofia óptica, ataxia, distonia ou insuficiência respiratória. Os procedimentos cirúrgicos e anestésicos provocam irritabilidade traqueal e podem exacerbar os riscos de aspiração, sibilação, dificuldade respiratória, respiração ofegante, hipoventilação e apneia. RELATO DE CASO: Apresentamos uma abordagem anestésica usada em um menino de seis anos com a forma grave de SL que envolve reparação de uma fratura de fêmur. Propofol e remifentanil foram infundidos para anestesia geral. O paciente foi atentamente monitorado durante a anestesia e sua permanência na unidade de terapia intensiva no período pós-operatório inicial. CONCLUSÕES: Uma atenta monitoração intraoperatória dos pacientes, que inclui pressão arterial invasiva e mensurações frequentes da gasometria, glicose e lactato, faz esse procedimento transcorrer sem problemas. A terapia intensiva e a assistência respiratória ao paciente com SL sob sedação, com uma combinação de analgésicos durante o período pós-operatório inicial, minimizaram a resposta ao estresse causado pela dor pós-cirúrgica.

  14. Mitochondrial vulnerability and increased susceptibility to nutrient-induced cytotoxicity in fibroblasts from leigh syndrome French canadian patients.

    Directory of Open Access Journals (Sweden)

    Yan Burelle

    Full Text Available Mutations in LRPPRC are responsible for the French Canadian variant of Leigh Syndrome (LSFC, a severe disorder characterized biochemically by a tissue-specific deficiency of cytochrome c oxidase (COX and clinically by the occurrence of severe and deadly acidotic crises. Factors that precipitate these crises remain unclear. To better understand the physiopathology and identify potential treatments, we performed a comprehensive analysis of mitochondrial function in LSFC and control fibroblasts. Furthermore, we have used this cell-based model to screen for conditions that promote premature cell death in LSFC cells and test the protective effect of ten interventions targeting well-defined aspects of mitochondrial function. We show that, despite maintaining normal ATP levels, LSFC fibroblasts present several mitochondrial functional abnormalities under normal baseline conditions, which likely impair their capacity to respond to stress. This includes mitochondrial network fragmentation, impaired oxidative phosphorylation capacity, lower membrane potential, increased sensitivity to Ca2+-induced permeability transition, but no changes in reactive oxygen species production. We also show that LSFC fibroblasts display enhanced susceptibility to cell death when exposed to palmitate, an effect that is potentiated by high lactate, while high glucose or acidosis alone or in combination were neutral. Furthermore, we demonstrate that compounds that are known to promote flux through the electron transport chain independent of phosphorylation (methylene blue, dinitrophenol, or modulate fatty acid (L-carnitine or Krebs cycle metabolism (propionate are protective, while antioxidants (idebenone, N-acetyl cysteine, resveratrol exacerbate palmitate plus lactate-induced cell death. Collectively, beyond highlighting multiple alterations in mitochondrial function and increased susceptibility to nutrient-induced cytotoxicity in LSFC fibroblasts, these results raise

  15. Mitochondrial Vulnerability and Increased Susceptibility to Nutrient-Induced Cytotoxicity in Fibroblasts from Leigh Syndrome French Canadian Patients

    Science.gov (United States)

    Burelle, Yan; Thompson Legault, Julie; Boucher, Gabrielle; Morin, Charles; Coderre, Lise; Des Rosiers, Christine

    2015-01-01

    Mutations in LRPPRC are responsible for the French Canadian variant of Leigh Syndrome (LSFC), a severe disorder characterized biochemically by a tissue-specific deficiency of cytochrome c oxidase (COX) and clinically by the occurrence of severe and deadly acidotic crises. Factors that precipitate these crises remain unclear. To better understand the physiopathology and identify potential treatments, we performed a comprehensive analysis of mitochondrial function in LSFC and control fibroblasts. Furthermore, we have used this cell-based model to screen for conditions that promote premature cell death in LSFC cells and test the protective effect of ten interventions targeting well-defined aspects of mitochondrial function. We show that, despite maintaining normal ATP levels, LSFC fibroblasts present several mitochondrial functional abnormalities under normal baseline conditions, which likely impair their capacity to respond to stress. This includes mitochondrial network fragmentation, impaired oxidative phosphorylation capacity, lower membrane potential, increased sensitivity to Ca2+-induced permeability transition, but no changes in reactive oxygen species production. We also show that LSFC fibroblasts display enhanced susceptibility to cell death when exposed to palmitate, an effect that is potentiated by high lactate, while high glucose or acidosis alone or in combination were neutral. Furthermore, we demonstrate that compounds that are known to promote flux through the electron transport chain independent of phosphorylation (methylene blue, dinitrophenol), or modulate fatty acid (L-carnitine) or Krebs cycle metabolism (propionate) are protective, while antioxidants (idebenone, N-acetyl cysteine, resveratrol) exacerbate palmitate plus lactate-induced cell death. Collectively, beyond highlighting multiple alterations in mitochondrial function and increased susceptibility to nutrient-induced cytotoxicity in LSFC fibroblasts, these results raise questions about the

  16. TRABAJO SEXUAL Y FEMINISMO, UNA FILIACIÓN BORRADA: TRADUCCIÓN DE "INVENTING SEX WORK" DE CAROL LEIGH (ALIAS SCARLOT HARLOT

    Directory of Open Access Journals (Sweden)

    Santiago Morcillo

    2016-01-01

    Full Text Available En esta introducción a la traducción del texto de Carol Leigh, reponemos brevemente el contexto de los debates feministas presentes en el surgimiento de la idea de trabajo sexual. Además brindamos una clave de lectura que permite comprender la importancia actual de esta traducción en el marco de una fuerte polarización del debate feminista sobre la prostitución y la transnacionalización de la campaña contra la trata de personas.

  17. Review of Shipwreck at Cape Flora: the expeditions of Benjamin Leigh Smith, England’s forgotten Arctic explorer, by P. J. Capelotti

    OpenAIRE

    Barr, Susan

    2013-01-01

    Research for this biography has taken the author from the United States to various parts of the United Kingdom and to Franz Josef Land, as well as drawing on his field experiences from Svalbard. His thoroughness in digging up material has produced a detailed account of the rather amazing life of the British eccentric Benjamin Leigh Smith.(Published: 12 September 2013)Citation: Polar Research 2013, 32, 22576, http://dx.doi.org/10.3402/polar.v32i0.22576

  18. Cartography of memory in Chris Marker and W.G. Sebald: Notes about History, memory and maps

    Directory of Open Access Journals (Sweden)

    Álvaro Brito

    2017-01-01

    Full Text Available This paper aims to approach the artists Chris Marker and W.G. Sebald, trying to determine and develop pervasive questions in their works: the construction of a historiographic discourse, the ambiguities of memory, the erratic movement of their characters and essayistic thinking. We have tried to draft some starting points to make possible the writing of a memory as a cartography, created through walking on the world and also through the collection of images and of stories that tell about lives that went astray in the mis-paths of History.

  19. Abordagem anestésica em paciente pediátrico com síndrome de Leigh Abordaje anestésico en paciente Pediátrico con el síndrome de Leigh Anesthetic management of a pediatric patient with Leigh syndrome

    Directory of Open Access Journals (Sweden)

    Ismail Serhat Kocamanoglu

    2013-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: A síndrome de Leigh (SL é uma doença rara causada por anomalias na produção de energia mitocondrial. O sistema nervoso central é afetado com mais frequência, com retardo psicomotor, convulsões, nistagmo, oftalmoparesia, atrofia óptica, ataxia, distonia ou insuficiência respiratória. Os procedimentos cirúrgicos e anestésicos provocam irritabilidade traqueal e podem exacerbar os riscos de aspiração, sibilação, dificuldade respiratória, respiração ofegante, hipoventilação e apneia. RELATO DE CASO: Apresentamos uma abordagem anestésica usada em um menino de seis anos com a forma grave de SL que envolve reparação de uma fratura de fêmur. Propofol e remifentanil foram infundidos para anestesia geral. O paciente foi atentamente monitorado durante a anestesia e sua permanência na unidade de terapia intensiva no período pós-operatório inicial. CONCLUSÕES: Uma atenta monitoração intraoperatória dos pacientes, que inclui pressão arterial invasiva e mensurações frequentes da gasometria, glicose e lactato, faz esse procedimento transcorrer sem problemas. A terapia intensiva e a assistência respiratória ao paciente com SL sob sedação, com uma combinação de analgésicos durante o período pós-operatório inicial, minimizaram a resposta ao estresse causado pela dor pós-cirúrgica.JUSTIFICATIVA Y OBJETIVOS: El síndrome de Leigh (SL es una enfermedad rara causada por anomalías en la producción de energía mitocondrial. El sistema nervioso central está afectado más a menudo, con el retardo psicomotor, convulsiones, nistagmo, oftalmoparesia, atrofia óptica, ataxia, distonía o insuficiencia respiratoria. Los procedimientos quirúrgicos y anestésicos provocan irritabilidad traqueal y pueden exacerbar los riesgos de aspiración, sibilancias, dificultad respiratoria, respiración extenuante, hipoventilación y apnea. RELATO DE CASO: Presentamos un abordaje anestésico usado en un niño de 6

  20. Synergistic angular and spectral estimation of aerosol properties using CHRIS/PROBA-1 and simulated Sentinel-3 data

    Directory of Open Access Journals (Sweden)

    W. H. Davies

    2014-06-01

    Full Text Available A method has been developed to estimate Aerosol Optical Depth (AOD, Fine Mode Fraction (FMF and Single Scattering Albedo (SSA over land surfaces using simulated Sentinel-3 data. The method uses inversion of a coupled surface/atmosphere radiative transfer model, and includes a general physical model of angular surface reflectance. An iterative process is used to determine the optimum value of the aerosol properties providing the best fit of the corrected reflectance values for a number of view angles and wavelengths with those provided by the physical model. A method of estimating AOD using only angular retrieval has previously been demonstrated on data from the ENVISAT and PROBA-1 satellite instruments, and is extended here to the synergistic spectral and angular sampling of Sentinel-3 and the additional aerosol properties. The method is tested using hyperspectral, multi-angle Compact High Resolution Imaging Spectrometer (CHRIS images. The values obtained from these CHRIS observations are validated using ground based sun-photometer measurements. Results from 22 image sets using the synergistic retrieval and improved aerosol models show an RMSE of 0.06 in AOD, reduced to 0.03 over vegetated targets.

  1. Mitochondrial respiratory chain enzyme assay and DNA analysis in peripheral blood leukocytes for the etiological study of Chinese children with Leigh syndrome due to complex I deficiency.

    Science.gov (United States)

    Ma, Yan Yan; Wu, Tong Fei; Liu, Yu Peng; Wang, Qiao; Li, Xi Yuan; Zhang, Yao; Song, Jin Qing; Wang, Yu Jie; Yang, Yan Ling

    2013-02-01

    Mitochondrial respiratory chain complex I enzyme deficiency is the most commonly seen mitochondrial respiratory chain disorder. Although screening and diagnostic methods are available overseas, clinically feasible diagnostic methods have not yet been established in China. In this study, four Chinese boys with Leigh syndrome due to complex I deficiency were diagnosed by mitochondrial respiratory chain enzyme assay and DNA analysis using peripheral blood leukocytes. Four patients were admitted at the age of 5-14 years because of unexplained progressive neuromuscular symptoms, including motor developmental delay or regression, weakness, and seizures. Their cranial magnetic resonance imaging revealed typical finding as Leigh syndrome. Peripheral leukocyte mitochondrial respiratory chain complex I activities were found decreased to 9.6-33.1 nmol/min/mg mitochondrial protein(control 44.0 ± 5.4 nmol/min/mg). The ratios of complex I to citrate synthase activity were also decreased (8.9-19.8% in patients vs. control 48 ± 11%). Three mtDNA mutations were identified from three out of four patients, supporting the diagnosis of complex I deficiency. Point mutations m.10191T>C in mitochondrial ND3 gene, m.13513G>A in ND5 gene and m.14,453G>A in ND6 gene were detected in three patients.

  2. 条带消除对于高光谱图像分类效果的影响--以CHRIS/PROBA图像为例%Effect of destriping on hyperspectral image classification, take CHRIS/PROBA as an example

    Institute of Scientific and Technical Information of China (English)

    梁建; 张杰; 马毅

    2015-01-01

    This paper takes CHRIS/PROBA hyperspectral images as an example. Image classifications are carried out on these original and destriped images by both unsupervised algorithm (ISODATA)and supervised algorithm (Maximum Likelihood, ML and Support Vector Machine, SVM ), and the results are analyzed. The results show that, destriping can well improve the visual effect of the classification by eliminating the burr between patches of different classes. This is very important for some researches that focus on the shape, geometry and distribution, such as landscape ecology. However, destriping cannot significantly improve the precision of classification;the maximum value of accuracy improvment is less than 2%.%以CHRIS/PROBA高光谱图像数据为例,使用非监督分类的ISODATA和监督分类的最大似然法、支持向量机等3种经典的图像分类算法,对消条带前后的图像分别开展分类实验,并对分类结果做了分析。实验结果表明,消条带处理可以较好地改善高光谱图像分类结果的目视效果,能够消除不同类别斑块边缘因条带而产生的“毛刺”现象,这对地物斑块的形状及几何分布敏感的研究(如景观生态学)至关重要;但消条带处理对于提高分类精度的效果并不显著,精度提高最大值不到2%。

  3. Petit Cinéma of the World or the Mysteries of Chris Marker

    Directory of Open Access Journals (Sweden)

    Susana S. Martins

    2010-01-01

    -pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

    Abstract (E: From 1954 to 1958, Chris Marker edited the travel books series Petite Planète, providing an alternative to more conventional guidebooks. The aim of this article is to pay special attention to the photographic dimension of these books, particularly in their essayistic composition. Starting from the concrete analysis of a short photo-sequence included in the book on Portugal, I propose here to investigate the central role of the ‘essay’ in the work of Chris Marker, not only as an aesthetical choice but fundamentally as a privileged form of political commitment.

     

    Abstract (F: De 1954 à 1958, Chris Marker fut rédacteur de la collection de livres de voyage Petite Planète, qui offrait une alternative aux guides de voyage plus classiques. Cet article vise à accorder une attention toute particulière à l'aspect photographique de ces livres, et plus spécialement à leur composition essayistique. À partir de l

  4. Short-term secular change in height, body mass and Tanner-Whitehouse 3 skeletal maturity of Madeira youth, Portugal.

    Science.gov (United States)

    Freitas, Duarte; Malina, Robert M; Maia, José; Lefevre, Johan; Stasinopoulos, Mikis; Gouveia, Élvio; Claessens, Albrecht; Thomis, Martine; Lausen, Berthold

    2012-05-01

    Secular trends in height and weight are reasonably well documented in Europe. Corresponding observations for skeletal maturation are lacking. To assess secular trends in height, body mass and skeletal maturity of Portuguese children and adolescents and to provide updated reference values for skeletal maturity scores (SMSs). Data for 2856 children and adolescents of 4-17 years, 1412 boys and 1444 girls, from The 'Madeira Growth Study' (MGS; 1996-1998) and from the'Healthy Growth of Madeira Children Study' (CRES; 2006) were used. Height and body mass were measured. Skeletal maturity was assessed with the Tanner-Whitehouse 2 and 3 methods. Children from CRES were taller and heavier than peers from MGS. Differences in height reached 5.8 cm in boys and 5.5 cm in girls. RUS SMSs did not differ consistently between surveys boys, while higher RUS scores were observed in CRES girls. Adult RUS SMSs for MGS and CRES combined were attained at 15.8 years in boys and 14.8 years in girls. Corresponding ages for adult Carpal SMSs were 14.4 and 14.0, respectively. The short-term trends for height and mass were not entirely consistent with the trends in RUS and Carpal SMSs and SAs.

  5. Evolution of skin grafting for treatment of burns: Reverdin pinch grafting to Tanner mesh grafting and beyond.

    Science.gov (United States)

    Singh, Mansher; Nuutila, Kristo; Collins, K C; Huang, Anne

    2017-09-01

    Skin grafting is the current standard care in the treatment of full thickness burns. It was first described around 1500 BC but the vast majority of advancements have been achieved over the past 200 years. An extensive literature review was conducted on Pubmed, Medline and Google Scholar researching the evolution of skin grafting techniques. The authors concentrated on the major landmarks of skin grafting and also provide an overview of ongoing research efforts in this field. The major innovations of skin grafting include Reverdin pinch grafting, Ollier grafting, Thiersch grafting, Wolfe grafting, Padgett dermatome and modifications, Meek-wall microdermatome and Tanner mesh grafting. A brief description of the usage, advantages and limitations of each technique is included in the manuscript. Skin grafting technique have evolved significantly over past 200 years from Reverdin pinch grafting to modern day meshed skin grafts using powered dermatome. Increasing the expansion ratio and improving the cosmetic and functional outcome are the main focus of ongoing skin grafting research and emerging techniques (such as Integra(®), Recell(®), Xpansion(®)) are showing promise. Copyright © 2017 Elsevier Ltd and ISBI. All rights reserved.

  6. Moral e direito nas "Tanner Lectures" de Habermas: um modelo processual de moralização do direito

    Directory of Open Access Journals (Sweden)

    Delamar Volpato Dutra

    2012-03-01

    Full Text Available http://dx.doi.org/10.5007/1677-2954.2011v10n3p13Pode-se defender que o positivismo se caracteriza, principalmente, pela tese da separação entre direito e moral. Com tal tese, o direito passa a ser explicado seja de forma completamente independente de qualquer teoria moral seja, em sua quintessência, por algum tipo de positivismo moral, como aquele defendido por Kelsen. Habermas, um dos críticos do positivismo, restabelece a conexão entre direito e moral, operando desse modo o que se poderia chamar de moralização ou remoralização do direito. Pretende-se apresentar, neste estudo, o modelo das Tanner Lectures [1986]. Neste texto, Habermas defende uma relação de subordinação do direito à moral; não obstante, uma subordinação processual, e não de conteúdos.

  7. Bender Visual-Motor Gestalt Test in adolescents: relationship between visual-motor development and the Tanner Stages.

    Science.gov (United States)

    Keppeke, Lívia de Freitas; Cintra, Isa de Pádua; Schoen, Teresa Helena

    2013-08-01

    Visual-motor skill is fundamental to human development and is an important component of psychological evaluations. The goal of the present study was to determine whether there is a correlation between visual-motor development, as measured by the Bender Visual-Motor Gestalt Test (Bender test), and sexual maturity in adolescents, based on the Tanner Stages in Adolescents. 134 adolescents from 10 to 15 years of age participated in the study. The Bender test and the Raven's Progressive Matrices Test were employed. The measures were administered individually and information on sexual maturity and the presence of developmental disorders was collected from medical charts. The results of the Bender test were not affected by gender, age, schooling, or changes stemming from puberty, but were significantly affected by having repeated a school year and by developmental disorders. An association was found with Raven's scores. The Bender test proved sensitive to developmental disorders in adolescence. No association was found between visual-motor development and sexual maturity in adolescents.

  8. Physical profile data from CTD casts from the RV Medeia in the coastal waters of Southeast Alaska in support of the SE Alaska Shrimp and Tanner Surveys from 06 September 2010 to 21 October 2010 (NODC Accession 0069122)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Alaska Department of Fish and Game conducts annual shellfish surveys that include Red King Crab, Tanner Crab, and Shrimp which is used to manage the personal...

  9. Estimation of leaf area index using an angular vegetation index based on in situ measurements and CHRIS/PROBA data

    Science.gov (United States)

    Wang, Lijuan; Zhang, Guimin; Lin, Hui; Liang, Liang; Niu, Zheng

    2016-06-01

    The Normalized Difference Vegetation Index (NDVI) is widely used for Leaf Area Index (LAI) estimation. It is well documented that the NDVI is extremely subject to the saturation problem when LAI reaches a high value. A new multi-angular vegetation index, the Hotspot-darkspot Difference Vegetation Index (HDVI) is proposed to estimate the high density LAI. The HDVI, defined as the difference between the hot and dark spot NDVI, relative to the dark spot NDVI, was proposed based on the Analytical two-layer Canopy Reflectance Model (ACRM) model outputs. This index is validated using both in situ experimental data in wheat and data from the multi-angular optical Compact High-Resolution Imaging Spectrometer (CHRIS) satellite. Both indices, the Hotspot-Darkspot Index (HDS) and the NDVI were also selected to analyze the relationship with LAI, and were compared with new index HDVI. The results show that HDVI is an appropriate proxy of LAI with higher determination coefficients (R2) for both the data from the in situ experiment (R2=0.7342, RMSE=0.0205) and the CHRIS data (R2=0.7749, RMSE=0.1013). Our results demonstrate that HDVI can make better the occurrence of saturation limits with the information of multi-angular observation, and is more appropriate for estimating LAI than either HDS or NDVI at high LAI values. Although the new index needs further evaluation, it also has the potential under the condition of dense canopies. It provides the effective improvement to the NDVI and other vegetation indices that are based on the red and NIR spectral bands.

  10. Comparison of observed rheological properties of hard wheat flour dough with predictions of the Giesekus-Leonov, White-Metzner and Phan-Thien Tanner models

    Science.gov (United States)

    Dhanasekharan, M.; Huang, H.; Kokini, J. L.; Janes, H. W. (Principal Investigator)

    1999-01-01

    The measured rheological behavior of hard wheat flour dough was predicted using three nonlinear differential viscoelastic models. The Phan-Thien Tanner model gave good zero shear viscosity prediction, but overpredicted the shear viscosity at higher shear rates and the transient and extensional properties. The Giesekus-Leonov model gave similar predictions to the Phan-Thien Tanner model, but the extensional viscosity prediction showed extension thickening. Using high values of the mobility factor, extension thinning behavior was observed but the predictions were not satisfactory. The White-Metzner model gave good predictions of the steady shear viscosity and the first normal stress coefficient but it was unable to predict the uniaxial extensional viscosity as it exhibited asymptotic behavior in the tested extensional rates. It also predicted the transient shear properties with moderate accuracy in the transient phase, but very well at higher times, compared to the Phan-Thien Tanner model and the Giesekus-Leonov model. None of the models predicted all observed data consistently well. Overall the White-Metzner model appeared to make the best predictions of all the observed data.

  11. Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells.

    Science.gov (United States)

    Iyer, Shilpa; Bergquist, Kristen; Young, Kisha; Gnaiger, Erich; Rao, Raj R; Bennett, James P

    2012-06-01

    Many incurable mitochondrial disorders result from mutant mitochondrial DNA (mtDNA) and impaired respiration. Leigh's syndrome (LS) is a fatal neurodegenerative disorder of infants, and Leber's hereditary optic neuropathy (LHON) causes blindness in young adults. Treatment of LHON and LS cells harboring G11778A and T8993G mutant mtDNA, respectively, by >90%, with healthy donor mtDNA complexed with recombinant human mitochondrial transcription factor A (rhTFAM), improved mitochondrial respiration by ∼1.2-fold in LHON cells and restored >50% ATP synthase function in LS cells. Mitochondrial replication, transcription, and translation of key respiratory genes and proteins were increased in the short term. Increased NRF1, TFAMB1, and TFAMA expression alluded to the activation of mitochondrial biogenesis as a mechanism for improving mitochondrial respiration. These results represent the development of a therapeutic approach for LHON and LS patients in the near future.

  12. Thiamine pyrophosphokinase deficiency causes a Leigh Disease like phenotype in a sibling pair: identification through whole exome sequencing and management strategies

    Directory of Open Access Journals (Sweden)

    Jamie L. Fraser

    2014-01-01

    Full Text Available We present a sibling pair with Leigh-like disease, progressive hypotonia, regression, and chronic encephalopathy. Whole exome sequencing in the younger sibling demonstrated a homozygous thiamine pyrophosphokinase (TPK mutation. Initiation of high dose thiamine, niacin, biotin, α-lipoic acid and ketogenic diet in this child demonstrated improvement in neurologic function and re-attainment of previously lost milestones. The diagnosis of TPK deficiency was difficult due to inconsistent biochemical and diagnostic parameters, rapidity of clinical demise and would not have been made in a timely manner without the use of whole exome sequencing. Molecular diagnosis allowed for attempt at dietary modification with cofactor supplementation which resulted in an improved clinical course.

  13. Política de los recuerdos y los olvidos. Zapping Zone una instalación de Chris Marker

    Directory of Open Access Journals (Sweden)

    Mikel Otxoteko

    2017-07-01

    Full Text Available Chris Marker es autor de una extensa obra audiovisual, a través de la cual trata de hallar una política de la forma capaz de constituir las imágenes como memoria colectiva. Su trayectoria artística está marcada por una intensa experimentación técnica y estilística en torno a la imagen audiovisual. Esta experimentación le conducirá a romper constantemente los moldes, llevando su propia expresión más allá de la inflexibilidad de las tradiciones y las disciplinas. Este ensayo regresa concretamente sobre un proyecto tardío, su instalación interactiva Zapping Zone, para analizar las técnicas de ensamblaje y las tácticas empleadas respecto al visitante de la instalación. La obra es un buen ejemplo de un personalísimo trabajo centrado en la escritura de la historia y en los procesos de la memoria colectiva. En ella, Marker no trata de imitar o reproducir los mecanismos individuales y sociales, sino justamente de crear las condiciones técnicas y estéticas para la producción de nuevas formas de recuerdo y olvido.

  14. Raamatututvustus / Oskar Tanner

    Index Scriptorium Estoniae

    Tanner, Oskar, pseud., 1939-

    1996-01-01

    Eliade, Mircea. Jaaniöö; Kippel, Enn. Kui Raudpea tuli; Beecher Stowe, Harriet. Onu Tomi onnike; Wallace, Edgar. Valge mask; Buchan, John. Kolm pantvangi; Rendell, Ruth. Hunditapp; Jurin, Artur. Näpsu

  15. Muusika / Kaie Tanner

    Index Scriptorium Estoniae

    Tanner, Kaie

    2004-01-01

    Kitarrimuusika päevad "Fiesta de la guitarra". Tallinna Tehnikaülikooli Kammerkoor ja Eesti Koolinoorte Segakoor edukad Veldhovenis toimunud VII rahvusvahelisel noortekooride konkursil. ETV tütarlastekoor edukas Tolosa 36. rahvusvahelisel koorikonkursil. Rahvusooperis kohtusid teatrihuvilised lavastaja Tiit Härmiga. Esmakordselt on Euroopa mainekates saalides kontsertreisil peadirigent Paavo Järvi koos Cincinnati Sümfooniaorkestriga. Eesti Teaduste Akadeemia Naiskoori tähtpäevakontserdil tuleb ettekandele Luis Bacalovi "Misa Tango". Oma debüüdi Jaapanis tegi pianistina Vardo Rumessen.

  16. Muusika / Kaie Tanner

    Index Scriptorium Estoniae

    Tanner, Kaie

    2004-01-01

    Kitarrimuusika päevad "Fiesta de la guitarra". Tallinna Tehnikaülikooli Kammerkoor ja Eesti Koolinoorte Segakoor edukad Veldhovenis toimunud VII rahvusvahelisel noortekooride konkursil. ETV tütarlastekoor edukas Tolosa 36. rahvusvahelisel koorikonkursil. Rahvusooperis kohtusid teatrihuvilised lavastaja Tiit Härmiga. Esmakordselt on Euroopa mainekates saalides kontsertreisil peadirigent Paavo Järvi koos Cincinnati Sümfooniaorkestriga. Eesti Teaduste Akadeemia Naiskoori tähtpäevakontserdil tuleb ettekandele Luis Bacalovi "Misa Tango". Oma debüüdi Jaapanis tegi pianistina Vardo Rumessen.

  17. Raamatututvustus / Oskar Tanner

    Index Scriptorium Estoniae

    Tanner, Oskar, pseud., 1939-

    1996-01-01

    Eliade, Mircea. Jaaniöö; Kippel, Enn. Kui Raudpea tuli; Beecher Stowe, Harriet. Onu Tomi onnike; Wallace, Edgar. Valge mask; Buchan, John. Kolm pantvangi; Rendell, Ruth. Hunditapp; Jurin, Artur. Näpsu

  18. Comparison Between Fractional Vegetation Cover Retrievals from Vegetation Indices and Spectral Mixture Analysis: Case Study of PROBA/CHRIS Data Over an Agricultural Area

    OpenAIRE

    Pablo Martinez; José Moreno; Luis Guanter; Antonio Plaza; José A Sobrino; Jiménez-Muñoz, Juan C.

    2009-01-01

    Abstract: In this paper we compare two different methodologies for Fractional Vegetation Cover (FVC) retrieval from Compact High Resolution Imaging Spectrometer (CHRIS) data onboard the European Space Agency (ESA) Project for On-Board Autonomy (PROBA) platform. The first methodology is based on empirical approaches using Vegetation Indices (VIs), in particular the Normalized Difference Vegetation Index (NDVI) and the Variable Atmospherically Resistant Index (VARI). The second methodology is b...

  19. SolidWorkS,在创新中发展--访SolidWorks公司Chris Garcia和Suchit Jain先生

    Institute of Scientific and Technical Information of China (English)

    杨芳

    2005-01-01

      在2005年SolidWorks全球用户大会举办期间,SolidWorks公司主管研发的副总裁Chris Garcia和分析软件事业部的副总裁Suchit Jain先生接受了我刊主编杨芳女士和e-works总经理黄培先生的专访.……

  20. SolidWorkS,在创新中发展--访SolidWorks公司Chris Garcia和Suchit Jain先生

    Institute of Scientific and Technical Information of China (English)

    杨芳

    2005-01-01

    @@ 在2005年SolidWorks全球用户大会举办期间,SolidWorks公司主管研发的副总裁Chris Garcia和分析软件事业部的副总裁Suchit Jain先生接受了我刊主编杨芳女士和e-works总经理黄培先生的专访.

  1. 阿拉伯船舶修造厂 方阿拉伯船舶修造厂首席执行官Chris Potter

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    美国《Maritime Reporter&Engineering News》杂志记者Greg Trauthwein,年初在巴林采访了阿拉伯船舶修造厂首席执行官Chris Potter,请他就船厂的发展方向以及业务多元化情况做—下介绍.以下为采访的具体内容。

  2. The Potential of Forest Biomass Inversion Based on Vegetation Indices Using Multi-Angle CHRIS/PROBA Data

    Directory of Open Access Journals (Sweden)

    Qiang Wang

    2016-10-01

    Full Text Available Multi-angle remote sensing can either be regarded as an added source of uncertainty for variable retrieval, or as a source of additional information, which enhances variable retrieval compared to traditional single-angle observation. However, the magnitude of these angular and band effects for forest structure parameters is difficult to quantify. We used the Discrete Anisotropic Radiative Transfer (DART model and the Zelig model to simulate the forest canopy Bidirectional Reflectance Distribution Factor (BRDF in order to build a look-up table, and eight vegetation indices were used to assess the relationship between BRDF and forest biomass in order to find the sensitive angles and bands. Further, the European Space Agency (ESA mission, Compact High Resolution Imaging Spectrometer onboard the Project for On-board Autonomy (CHRIS-PROBA and field sample measurements, were selected to test the angular and band effects on forest biomass retrieval. The results showed that the off-nadir vegetation indices could predict the forest biomass more accurately than the nadir. Additionally, we found that the viewing angle effect is more important, but the band effect could not be ignored, and the sensitive angles for extracting forest biomass are greater viewing angles, especially around the hot and dark spot directions. This work highlighted the combination of angles and bands, and found a new index based on the traditional vegetation index, Atmospherically Resistant Vegetation Index (ARVI, which is calculated by combining sensitive angles and sensitive bands, such as blue band 490 nm/−55°, green band 530 nm/55°, and the red band 697 nm/55°, and the new index was tested to improve the accuracy of forest biomass retrieval. This is a step forward in multi-angle remote sensing applications for mining the hidden relationship between BRDF and forest structure information, in order to increase the utilization efficiency of remote sensing data.

  3. Clinical and molecular features of an infant patient affected by Leigh Disease associated to m.14459G > A mitochondrial DNA mutation: a case report

    Directory of Open Access Journals (Sweden)

    Moggio Maurizio

    2011-07-01

    Full Text Available Abstract Background Leigh Syndrome (LS is a severe neurodegenerative disorder characterized by bilateral symmetrical necrotic lesions in the basal ganglia and brainstem. Onset is in early infancy and prognosis is poor. Causative mutations have been disclosed in mitochondrial DNA and nuclear genes affecting respiratory chain subunits and assembly factors. Case presentation Here we report the clinical and molecular features of a 15-month-old female LS patient. Direct sequencing of her muscle-derived mtDNA revealed the presence of two apparently homoplasmic variants: the novel m.14792C > G and the already known m.14459G > A resulting in p.His16Asp change in cytochrome b (MT-CYB and p.Ala72Val substitution in ND6 subunit, respectively. The m.14459G > A was heteroplasmic in the mother's blood-derived DNA. Conclusions The m.14459G > A might lead to LS, complicated LS or Leber Optic Hereditary Neuropathy. A comprehensive re-evaluation of previously described 14459G > A-mutated patients does not explain this large clinical heterogeneity.

  4. CHRIS: Hazardous Chemical Data

    Science.gov (United States)

    1978-10-01

    Syrrinis: 41% tipos ond PhryicalStte (e hipped): 12 llSaadaNrgnukaee 17Seitcedt 74aS lpl - Onlhlpopaontrio.42 Col I,,(lcoro Teaneporwtaan Not 1,mxd 138 liud...No o beUsd- 4Id. 64~ Food Cha.n Co,, contrato , Pot .nfi.f &£!I SpecialIHtads ofConmbiorti Plodwcts 66 Blotn po. ,, 68a EJeoteCit Huard. %.1~ 69 Bruening...I. .Wbf- hq - rif 0 e uospI. ,d n. cna 134ollutioPint C EPICALT DSIAION 4. OBERABEL HARACTERISTICSN COD 13.HSC N C HEMI~ tiPO ICAL ?ROPERTI J , . . l.d

  5. CHRIS. Response Methods Handbook.

    Science.gov (United States)

    1978-12-01

    impossible, however, to establish hard and fast rules for response actions since the terrain, water conditions, and even blend - ing of one or more chemical...IV IOUSIl\\ trcLAteL.’I. luecaiie Ia) thle Nilif)’N \\ak Antjii propeler at loll can brak up t ie slick andL pcrliaps ilik Noni11 Oif (lie bnrnIin agent

  6. CHRIS: Hazard Assessment Handbook

    Science.gov (United States)

    1977-12-12

    CODE AIJ 91 HAZARD ASSESSMENT CODE-ABC KLMN 95 A. VENTING GAS FIRE -CODE AB 97 B. LIOUID FIRE-CODE AKL 97 C. WATER POLLUTION HAZARDS - CODE AK 99 D...The Hazard Calculation Codes for liquefied natural gas are: AB — venting gas fire . AC - gas dispersion, ADE — liquid fire, and ADFG...5.4). Spill Amount Wind Velocity Wind Direction Weather ppm tons knots Primary Code ABCKLMN Code AB - Venting Gas Fire Assessment

  7. Status of referral to physiotherapy among hiv positive patients at Chris Hani Baragwaneth hospital johannesburg South Africa 2005

    Directory of Open Access Journals (Sweden)

    H. Myezwa

    2007-02-01

    Full Text Available HIV continues to be a major health problem in South Africa.The multiple diagnoses that the disease presents with, needs a holistic and comprehensive management approach. Physiotherapy and rehabilitation play a role in this management approach. Understanding the full scope of conditions that are present and those that are suitable for physiotherapy intervention is an essential prerequisite to developing appropriate curricula, intervention models or systems. It is accepted that HIV rehabilitation interventions are based largely on functional deficits ( O’Dell  1996, however  in South Africa functional deficits have not been fully explored. A common starting point, with the medical model of management was considered to be at the diagnosis level as this information would be more readily available than functional deficits.Purpose: This study aimed to establish how much and in which aeitiology is physiotherapy involved in the management of HIV within an inpatient hospital setting at Chris Hani Baragwaneth Hospital. This minor study forms part of a larger study establishing physiotherapy curricula needs.Method: Aretrospective review of patient records was carried out in order to identify conditions suitable for physiotherapy and to determine the referral patterns to physiotherapy.Findings: Of the 732 records reviewed and used in the study, 47% (n=344 of the patients were HIV positive. From theserecords, 19% (n=139 had diagnoses considered suitable for physiotherapy and only 2% (n=3 of these 139 patientswere referred to physiotherapy.Conclusion: Almost half of the patients in the medical units were HIV positive. Although the referral rate was verylow, some of these patients presented with diagnosis that are traditionally seen by physiotherapists.  None of the patients’records indicated examination of the patients’ physical status such as exercise tolerance, mobility, muscle strength,lung function or pain. This study is by no means fully

  8. Peristaltic Flow and Heat Transfer of a Conducting Phan-Thien-Tanner Fluid in an Asymmetric Channel - Application to Chyme Movement in Small Intestine

    Science.gov (United States)

    Vajravelu, K.; Sreenadh, S.; Dhananjaya, S.; Lakshminarayana, P.

    2016-08-01

    In this paper, the influence of heat transfer on the peristaltic flow of a conducting Phan-Thien-Tanner fluid in an asymmetric channel with porous medium is studied. The coupled nonlinear governing differential equations are solved by a perturbation technique. The expressions for the temperature field, the stream function, the axial velocity, and the pressure gradient are obtained. The effects of the various physical parameters such as the magnetic parameter M, the permeability parameter σ, the Brinkman number Br and the Weissenberg number We on the pumping phenomenon are analyzed through graphs and the results are discussed in detail. It is observed that the velocity and the pressure are decreased with increasing the magnetic parameter M whereas the effect of the parameter M on the temperature field is quite the opposite.

  9. Effects of ocean acidification on juvenile red king crab (Paralithodes camtschaticus) and Tanner crab (Chionoecetes bairdi) growth, condition, calcification, and survival.

    Science.gov (United States)

    Long, William Christopher; Swiney, Katherine M; Harris, Caitlin; Page, Heather N; Foy, Robert J

    2013-01-01

    Ocean acidification, a decrease in the pH in marine waters associated with rising atmospheric CO2 levels, is a serious threat to marine ecosystems. In this paper, we determine the effects of long-term exposure to near-future levels of ocean acidification on the growth, condition, calcification, and survival of juvenile red king crabs, Paralithodes camtschaticus, and Tanner crabs, Chionoecetes bairdi. Juveniles were reared in individual containers for nearly 200 days in flowing control (pH 8.0), pH 7.8, and pH 7.5 seawater at ambient temperatures (range 4.4-11.9 °C). In both species, survival decreased with pH, with 100% mortality of red king crabs occurring after 95 days in pH 7.5 water. Though the morphology of neither species was affected by acidification, both species grew slower in acidified water. At the end of the experiment, calcium concentration was measured in each crab and the dry mass and condition index of each crab were determined. Ocean acidification did not affect the calcium content of red king crab but did decrease the condition index, while it had the opposite effect on Tanner crabs, decreasing calcium content but leaving the condition index unchanged. This suggests that red king crab may be able to maintain calcification rates, but at a high energetic cost. The decrease in survival and growth of each species is likely to have a serious negative effect on their populations in the absence of evolutionary adaptation or acclimatization over the coming decades.

  10. Effects of ocean acidification on juvenile red king crab (Paralithodes camtschaticus and Tanner crab (Chionoecetes bairdi growth, condition, calcification, and survival.

    Directory of Open Access Journals (Sweden)

    William Christopher Long

    Full Text Available Ocean acidification, a decrease in the pH in marine waters associated with rising atmospheric CO2 levels, is a serious threat to marine ecosystems. In this paper, we determine the effects of long-term exposure to near-future levels of ocean acidification on the growth, condition, calcification, and survival of juvenile red king crabs, Paralithodes camtschaticus, and Tanner crabs, Chionoecetes bairdi. Juveniles were reared in individual containers for nearly 200 days in flowing control (pH 8.0, pH 7.8, and pH 7.5 seawater at ambient temperatures (range 4.4-11.9 °C. In both species, survival decreased with pH, with 100% mortality of red king crabs occurring after 95 days in pH 7.5 water. Though the morphology of neither species was affected by acidification, both species grew slower in acidified water. At the end of the experiment, calcium concentration was measured in each crab and the dry mass and condition index of each crab were determined. Ocean acidification did not affect the calcium content of red king crab but did decrease the condition index, while it had the opposite effect on Tanner crabs, decreasing calcium content but leaving the condition index unchanged. This suggests that red king crab may be able to maintain calcification rates, but at a high energetic cost. The decrease in survival and growth of each species is likely to have a serious negative effect on their populations in the absence of evolutionary adaptation or acclimatization over the coming decades.

  11. 访美国SolidWorks 公司研发副总裁Chris Garcia专注三维CAD创业界领先

    Institute of Scientific and Technical Information of China (English)

    江彦

    2005-01-01

    @@ Chris Garcia,是美国SolidWorks公司研发副总裁.每年,他将两次到中国进行工作访问,一方面了解中国用户的最新市场需求,另一方面,他还要到杭州与叶修梓博士带领的团队--事实上的SolidWorks公司在全球的第五个研发中心进行工作研讨和检查.

  12. A novel frameshift mutation of the mtDNA COIII gene leads to impaired assembly of cytochrome c oxidase in a patient affected by Leigh-like syndrome.

    Science.gov (United States)

    Tiranti, V; Corona, P; Greco, M; Taanman, J W; Carrara, F; Lamantea, E; Nijtmans, L; Uziel, G; Zeviani, M

    2000-11-01

    We report on a novel frameshift mutation in the mtDNA gene encoding cytochrome c oxidase (COX) subunit III. The proband is an 11-year-old girl with a negative family history and an apparently healthy younger brother. Since 4 years of age, she has developed a progressive spastic paraparesis associated with ophthalmoparesis and moderate mental retardation. The presence of severe lactic acidosis and Leigh-like lesions of putamina prompted us to perform muscle and skin biopsies. In both, a profound, isolated defect of COX was found by histochemical and biochemical assays. Sequence analysis of muscle mtDNA resulted in the identification of a virtually homoplasmic frameshift mutation in the COIII gene, due to the insertion of an extra C at nucleotide position 9537 of mtDNA. Although the 9537C(ins) does not impair transcription of COIII, no full-length COX III protein was detected in mtDNA translation assays in vivo. Western blot analysis of two-dimensional blue-native electrophoresis showed a reduction of specific crossreacting material and the accumulation of early-assembly intermediates of COX, whereas the fully assembled complex was absent. One of these intermediates had an electrophoretic mobility different from those seen in controls, suggesting the presence of a qualitative abnormality of COX assembly. Immunostaining with specific antibodies failed to detect the presence of several smaller subunits in the complex lacking COX III, in spite of the demonstration that these subunits were present in the crude mitochondrial fraction of patient's cultured fibroblasts. Taken together, the data indicate a role for COX III in the incorporation and maintenance of smaller COX subunits within the complex.

  13. Clinical and biochemical characterization of 3-hydroxyisobutyryl-CoA hydrolase (HIBCH deficiency that causes Leigh-like disease and ketoacidosis

    Directory of Open Access Journals (Sweden)

    Kenichiro Yamada

    2014-01-01

    Full Text Available 3-Hydroxyisobutyryl-CoA hydrolase (HIBCH deficiency is an autosomal recessive disorder characterized by episodes of ketoacidosis and a Leigh-like basal ganglia disease, without high concentrations of pyruvate and lactate in the cerebrospinal fluid. Only 4 cases of HIBCH deficiency have been reported. However, clinical–biochemical correlation in HIBCH deficiency by determining the detailed residual enzyme activities has not yet been elucidated. Here, we report a case of two Japanese siblings with HIBCH deficiency carrying a new homozygous missense mutation (c.287C > A, [p.A96D] at the substrate-binding site. A transfection study using HIBCH expression vectors harboring wild type or 4 reported mutations, including the newly identified mutation (p.A96D, p.Y122C, p.G317E, and p.K74Lfs*13, revealed a correlation between residual HIBCH activities and the severity of the disease. All HIBCH mutants, except p.K74Lfs*13, showed residual enzyme activity and only the patient with p.K74Lfs*13 had congenital anomalies. p.G317E showed only low enzyme activity (~3% of that of wild-type HIBCH. Although p.A96D had approximately 7 times higher enzyme activity than p.G317E, patients with p.A96D died during childhood. These findings are essential for clinical management, genetic counseling, and specific meal and concomitant drug considerations as part of the treatment for patients with HIBCH deficiency.

  14. 一类扩散Holling-Tanner模型行波解的存在性%THE EXISTENCE OF TRAVELLING WAVE SOLUTIONS OF THE DIFFUSION HOLLING-TANNER MODEL

    Institute of Scientific and Technical Information of China (English)

    蒋松; 罗勇

    2012-01-01

    In ecology, the variation of population's density as time evolves and space changes can be described by nonlinear reaction diffusion equations. By considering the asymptotic behavior of the differential equation models, the survival or extinction of the species can be obtained. In the study of nonlinear reaction diffusion equations, it is convenient to study travelling wave solution for its simple form. And it provides some ways for the study of dynamic behavior of the partial differential equations. In this paper, we study qualitative analysis on the diffusion Holling-Tanner system, find the sufficient condition of system local asymptotic stability. By constructing a Liapunov function, we obtain the condition of local asymptotic stability for the diffusion Holling-Tanner system, and then get the sufficient condition for the existence of traveling wave solutions. At last, we give some examples of numerical simulation as well.%在生态学中,可以用非线性反应扩散方程来描述种群在时间上的变化和在空间中的分布及扩散情况.对于扩散的生物种群模型,通过研究模型中方程的渐近性态,可以知道该种群是持续生存还是趋向灭绝.在非线性反应扩散方程的研究中,行波解由于其形式简单,研究比较方便,为研究偏微分方程的动力学行为提供了一些途径.文章对一类添加扩散项的扩散Holling-Tanner系统进行了定性分析,得到了系统平衡点局部渐近稳定的充分条件.再通过构造Liapunov函数的方法,得到扩散Holling-Tanner系统平衡点全局渐近稳定的条件,以及该系统行波解存在的充分条件,并进行了数值模拟.

  15. L’adresse du lointain. La mémoire au travail chez Michaux, Burroughs, K. Dick, Chris Marker et Ricardo Piglia

    Directory of Open Access Journals (Sweden)

    Anne Bourse

    2009-07-01

    Full Text Available Cet article analyse quelques variations de la formule épistolaire de Michaux : « Je vous écris d’un pays lointain… » Le dépliement d’autres figures de voyageurs tels que Burroughs (The Yage Letters, Philip K. Dick (Ubik, Chris Marker (Sans Soleil, Le Dépays et Ricardo Piglia (Respiración artificial révèle que le « lointain » se loge parfois au plus intime (du corps propre, d’une grammaire familière et qu’il ne cesse de brouiller les frontières séparant habituellement les morts des vivants. Adressé depuis divers ailleurs, ce travail de la mémoire cherche autant à suturer qu’à creuser l’inquiétante disjointure des temps.In this article we will analyze a number of variations of Michaux’s epistolary formula: “I am writing to you from a faraway country…” By unfolding other travelers’ figures such as Burroughs’ (The Yage Letters, Philip K. Dick’s (Ubik, Chris Marker’s (Sunless, Le Dépays and Ricardo Piglia’s (Respiración artificial, we will examine how “remoteness” is sometimes lodged within the deepest intimacy (the body itself, a familiar grammar and we will take a closer look at the way it constantly blurs, moves and disquiets the lines existing between the living and the dead. Enunciated and sent out from different elsewheres, this work on memory seeks as much to stitch up as to deepen time’s unsettling spinning out of joint.Este artículo analiza algunas variaciones de la fórmula epistolar de Michaux : “Le escribo de un país lejano…”. La similitud con otros viajeros presentes en la obra de Burroughs (The Yage Letters, de Philip K. Dick (Ubik, de Chris Marker (Sans soleil, Le Dépays y de Ricardo Piglia (Respiración artificial revela que lo "lejano" habita a veces en lo más íntimo (del propio cuerpo, de una gramática familiar y que no deja de desdibujar las fronteras que habitualmente separan a los muertos de los vivos. Dirigido desde sitios muy diversos, este trabajo de

  16. Steady flow and heat transfer analysis of Phan-Thein-Tanner fluid in double-layer optical fiber coating analysis with Slip Conditions

    Science.gov (United States)

    Khan, Zeeshan; Shah, Rehan Ali; Islam, Saeed; Jan, Bilal; Imran, Muhammad; Tahir, Farisa

    2016-10-01

    Modern optical fibers require double-layer coating on the glass fiber to provide protection from signal attenuation and mechanical damage. The most important plastic resins used in wires and optical fibers are plastic polyvinyl chloride (PVC) and low-high density polyethylene (LDPE/HDPE), nylon and Polysulfone. In this paper, double-layer optical fiber coating is performed using melt polymer satisfying PTT fluid model in a pressure type die using wet-on-wet coating process. The assumption of fully developed flow of Phan-Thien-Tanner (PTT) fluid model, two-layer liquid flows of an immiscible fluid is modeled in an annular die, where the fiber is dragged at a higher speed. The equations characterizing the flow and heat transfer phenomena are solved exactly and the effects of emerging parameters (Deborah and slip parameters, characteristic velocity, radii ratio and Brinkman numbers on the axial velocity, flow rate, thickness of coated fiber optics, and temperature distribution) are reported in graphs. It is shown that an increase in the non-Newtonian parameters increase the velocity in the absence or presence of slip parameters which coincides with related work. The comparison is done with experimental work by taking λ → 0 (non-Newtonian parameter).

  17. The relationship between circulating ecdysteroids and chela allometry in male tanner crabs: Evidence for a terminal molt in the genus Chionoecetes

    Science.gov (United States)

    Tamone, S.L.; Taggart, S.J.; Andrews, A.G.; Mondragon, J.; Nielsen, J.K.

    2007-01-01

    Whether male Tanner crabs, Chionoecetes bairdi, undergo a terminal molt associated with a change in claw allometry has long been debated. We measured molting hormone levels in captured male C. bairdi to assess the potential for molting. We plotted a frequency histogram of chela height to carapace width ratios and found a bimodal distribution of crabs with a ratio of approximately 0.18 separating the two modes. Male crabs with a ratio less than 0.18 were classified as "small-clawed" (SC) while crabs with a ratio greater than 0.18 were classified as "large-clawed" (LC). Circulating molting hormones between SC and LC crabs were compared. Significantly lower ecdysteroid levels were found in LC crabs, indicating that this morphotype had negligible potential for molting. Circulating ecdysteroids were measured in SC males of different shell conditions (soft, new, old, and very old) and no significant differences were found. This research suggests that the molt to LC morphology is a terminal molt. The results from this study have important implications for fisheries management because sub-legal LC males will not recruit into the fishery and removal of larger males may have long term effects on population size structure.

  18. Steady flow and heat transfer analysis of Phan-Thein-Tanner fluid in double-layer optical fiber coating analysis with Slip Conditions

    Science.gov (United States)

    Khan, Zeeshan; Shah, Rehan Ali; Islam, Saeed; Jan, Bilal; Imran, Muhammad; Tahir, Farisa

    2016-01-01

    Modern optical fibers require double-layer coating on the glass fiber to provide protection from signal attenuation and mechanical damage. The most important plastic resins used in wires and optical fibers are plastic polyvinyl chloride (PVC) and low-high density polyethylene (LDPE/HDPE), nylon and Polysulfone. In this paper, double-layer optical fiber coating is performed using melt polymer satisfying PTT fluid model in a pressure type die using wet-on-wet coating process. The assumption of fully developed flow of Phan-Thien-Tanner (PTT) fluid model, two-layer liquid flows of an immiscible fluid is modeled in an annular die, where the fiber is dragged at a higher speed. The equations characterizing the flow and heat transfer phenomena are solved exactly and the effects of emerging parameters (Deborah and slip parameters, characteristic velocity, radii ratio and Brinkman numbers on the axial velocity, flow rate, thickness of coated fiber optics, and temperature distribution) are reported in graphs. It is shown that an increase in the non-Newtonian parameters increase the velocity in the absence or presence of slip parameters which coincides with related work. The comparison is done with experimental work by taking λ → 0 (non-Newtonian parameter). PMID:27708412

  19. Comparison Between Fractional Vegetation Cover Retrievals from Vegetation Indices and Spectral Mixture Analysis: Case Study of PROBA/CHRIS Data Over an Agricultural Area

    Directory of Open Access Journals (Sweden)

    Pablo Martinez

    2009-02-01

    Full Text Available In this paper we compare two different methodologies for Fractional Vegetation Cover (FVC retrieval from Compact High Resolution Imaging Spectrometer (CHRIS data onboard the European Space Agency (ESA Project for On-Board Autonomy (PROBA platform. The first methodology is based on empirical approaches using Vegetation Indices (VIs, in particular the Normalized Difference Vegetation Index (NDVI and the Variable Atmospherically Resistant Index (VARI. The second methodology is based on the Spectral Mixture Analysis (SMA technique, in which a Linear Spectral Unmixing model has been considered in order to retrieve the abundance of the different constituent materials within pixel elements, called Endmembers (EMs. These EMs were extracted from the image using three different methods: i manual extraction using a land cover map, ii Pixel Purity Index (PPI and iii Automated Morphological Endmember Extraction (AMEE. The different methodologies for FVC retrieval were applied to one PROBA/CHRIS image acquired over an agricultural area in Spain, and they were calibrated and tested against in situ measurements of FVC estimated with hemispherical photographs. The results obtained from VIs show that VARI correlates better with FVC than NDVI does, with standard errors of estimation of less than 8% in the case of VARI and less than 13% in the case of NDVI when calibrated using the in situ measurements. The results obtained from the SMA-LSU technique show Root Mean Square Errors (RMSE below 12% when EMs are extracted from the AMEE method and around 9% when extracted from the PPI method. A RMSE value below 9% was obtained for manual extraction of EMs using a land cover use map.

  20. PeoplePersonality: Chris Clarke - a physicist who studies ice cream Teaching Anecdotes: Annie Jump Cannon Obituary: György Marx 1927-2002 Starting Out: What Katie did next: part 3 Opinions: What is really important?

    Science.gov (United States)

    2003-03-01

    Featuring relationships, personalities, interactions, environments and reputations involved in physics and education PERSONALITY (156) Chris Clarke - a physicist who studies ice cream TEACHING ANECDOTES (157) Annie Jump Cannon OBITUARY (158) György Marx 1927-2002 Steven Chapman STARTING OUT (159) What Katie did next: part 3 Katie Pennicott OPINIONS (160) What is really important? Kerry Parker

  1. Review: Chris Alden, Sergio Chichava (eds, China and Mozambique: From Comrades to Capitalists (2014 / Giles Mohan et al., Chinese Migrants and Africa’s Development: New Imperialists or Agents of Change? (2014

    Directory of Open Access Journals (Sweden)

    Laurence Marfaing

    2015-01-01

    Full Text Available Review of: Chris Alden and Sergio Chichava (eds, China and Mozambique: From Comrades to Capitalists, Johannesburg: Jacana Media, 2014, ISBN 9781920196943, 240 pp.andGiles Mohan, Ben Lampert, May Tan-Mullins and Daphne Chang, Chinese Migrants and Africa’s Development: New Imperialists or Agents of Change?, London: Zed Books, 2014, ISBN 9781780329178, 192 pp.

  2. Stanley Kubrik. Chantal Akerman, Críticas: Beto Gómez, Ignacio Siro Medrano, Juan José Campanella, Abbas Kiarostami, Luis Eduardo Aute, Chris Columbus, J. K. Rowling

    OpenAIRE

    La madriguera

    2002-01-01

    La madriguera (2002). Stanley Kubrik. Chantal Akerman, Críticas: Beto Gómez, Ignacio Siro Medrano, Juan José Campanella, Abbas Kiarostami, Luis Eduardo Aute, Chris Columbus, J. K. Rowling. Ediciones de intervención cultural S.L. http://hdl.handle.net/10251/42047. 62 62 46

  3. Genetics Home Reference: Leigh syndrome

    Science.gov (United States)

    ... found in DNA in specialized structures in the cell called mitochondria . This type of DNA is known as mitochondrial ... MT-ATP6 . Because egg cells, but not sperm cells, contribute mitochondria to the developing embryo, children can inherit disorders ...

  4. Truth Created by Improvisation——An Analysis of Mike Leigh's Theatre/Film Rehearsals%即兴创造真实——麦克·李的戏剧/电影前期排练解析

    Institute of Scientific and Technical Information of China (English)

    刘阳

    2009-01-01

    @@ 谁是麦克·李(Mike Leigh) 第58届柏林电影节于北京时间2008年2月17日落下帷幕,之前广受好评的影片《无忧无虑》(Happy-Go-Lucky)只获得最佳女演员奖,使这次金熊奖的评选备受争议.但是这部影片的导演--伦敦电影学院的主席,被誉为英国电影教父之一的麦克·李--已经不需靠再次获奖来增加头上的光环.

  5. Determination of seasonal changes in wetlands using CHRIS/Proba Hyperspectral satellite images: A case study from Acigöl (Denizli), Turkey.

    Science.gov (United States)

    Karaman, Muhittin; Budakoglu, Murat; Avci, Damla Uca; Ozelkan, Emre; Bulbul, Ali; Civas, Melda; Tasdelen, Suat

    2015-01-01

    The changes in wetlands that occur through natural processes, as well as through industrialization and agricultural activities, are decreasing and even annihilating the living spaces of endemic species. Acigöl (Denizli, Turkey), which is a suitable habitat for flamingos (Phoenicopterus ruber), is a lake that is affected by seasonal anomalies as a result of being shallow. Acigöl, which is fed by precipitation, groundwater and the springs that occur along tectonic faults, has no water output other than evaporation and industrial activities. In addition to natural factors, it is important to determine the changes in the wetlands of Acig6l, where industrial salt is produced, in order to reveal the micro-ecological equilibrium, the relationship between climate and natural life, and regulation of industrial activities. Remote sensing tools are frequently used in determination of changes in wetlands. Changes in coastlines, water level and area covered by water are parameters that can be examined by remote sensing while investigating wetlands. In this study, the water-covered area was examined using remote sensing. Within the scope of this study, CHRIS/Proba Mode 2 (water bandset) hyperspectral satellite images, acquired on 9/17/2011 for the season and on 6/18/2012 - 6/19/2012 forwet season, were used in orderto present the seasonal changes in Acigöl, during one hydrogeological period. The processes of noise reduction, cloud screening, atmospheric correction, geometric correction, and identification of wetlands have been implemented on the CHRIS/Proba images. In determining the water-covered areas, the Normalized Difference Water Index (NDWI) was used. It was determined that W6 (560 nm) and W18 (1015 nm) and W2 (447 nm) and W18 (1015 nm) band combinations were most appropriate to be used in NDWI to demonstrate the water-land separation. Using Proba-NDWI image, it was established that an area of 27.4 km2 was covered with water during dry season, and 61.2 km2 was covered

  6. Variabilidad de la presión arterial en 24 horas en adolescentes obesas y no-obesas con desarrollo mamario 4 y 5 de los criterios de Tanner Blood pressure variability in 24 hours in obese and non-obese adolescents with breast development 4 and 5 of Tanner's criteria

    Directory of Open Access Journals (Sweden)

    I. C. Bonilla Rosales

    2011-10-01

    Full Text Available Objetivo: Investigar el comportamiento de la presión arterial (PA mediante monitoreo ambulatorio de la presión arterial (MAPA en 24 h en un grupo de adolescentes obesas y no-obesas con estadios mamarios de Tanner 4 y 5. Métodos: Estudio transversal realizado en el Instituto de Investigación Cardiovascular en México, incluyendo 64 adolescentes entre 13 a 16 años de edad con estadios mamarios 4 o 5 de la clasificación de Tanner. Se midió PA en la oficina, frecuencia cardiaca (FC, índice de masa corporal (IMC, índice cintura-cadera, circunferencia de brazo, pliegues cutáneos tricipital, subescapular, abdominal y supraespinal. Se analizaron PA con MAPA en 24 h en obesas y no-obesas. Resultados: Cincuenta y nueve adolescentes, 29 obesas (IMC 31,2 ± 4,0 y 30 no-obesas (IMC 21,2 ± 2,2. Obesas vs no-obesas PAs en la oficina 116,9 vs 105,9 ± 9,3 mmHg (p Objective: The aim of the study was to investigate the blood pressure variability during 24 h by using ambulatory blood pressure monitoring (ABPM in a group of obese and non-obese female adolescents with breast development status 4 and 5 of Tanner´s criteria. Methods: A cross-sectional study was conducted at the Cardiovascular Research Institute, Mexico. All subjects underwent 24 h non-invasive ABPM recording device. Pubertal status was determined by breast development. Measurements: office systolic blood pressure (SBP, diastolic blood pressure (DBP, and heart rate (HR. Height, weight, body mass index (BMI, waist and hip circumferences, arm circumference, waist to hip ratio (W/H, and skinfold thickness measurements: triceps, subscapular, abdominal and supraspinal. Results: Fifty-nine adolescents 13-16 years old; 29 obese (BMI 31.2 ± 4.0, and 30 non- obese (BMI 21.2 ± 2.2. Obese vs. non-obese: Office SBP 116.9 vs. 105.9 ± 9.3 mmHg (p < 0.001; ABPM in 24 h: SBP 113.8 ± 6.3 vs. 107.6 ± 5.7 mmHg (p < 0.001; diurnal SBP 117.3 mmHg vs. 111.2 mmHg (p < 0.001; nocturnal SBP 105.5 ± 8 vs. 99

  7. Occurrence of Vibrio Pathotypes in the Final Effluents of Five Wastewater Treatment Plants in Amathole and Chris Hani District Municipalities in South Africa

    Directory of Open Access Journals (Sweden)

    Vuyokazi Nongogo

    2014-08-01

    Full Text Available We assessed the occurrence of Vibrio pathogens in the final effluents of five wastewater treatment plants (WWTPs located in Amathole and Chris Hani District Municipalities in South Africa over a 12 months period between September 2012 and August 2013 using standard membrane filtration technique followed by cultivation on thiosulphate citrate-bile salts-sucrose (TCBS agar. The identities of the presumptive Vibrio isolates were confirmed using polymerase chain reaction (PCR including delineation into V. parahaemolyticus, V. vulnificus and V. fluvialis pathotypes. The counts of Vibrio spp. varied with months in all the study sites and ranged in the order of 101 and 104 CFU/100mL. Vibrio distribution also showed seasonality with high counts being obtained in autumn and spring (p < 0.05. Prevalence of Vibrio spp. among the five WWTPs also differed significantly (p < 0.05. Of the 300 isolates that were confirmed as belonging to the Vibrio genus, 29% (86 were V. fluvialis, 28% (84 were V. vulnificus and 12% (35 were V. parahaemolyticus. The isolation of Vibrio pathogens from the final effluent suggests that this pathogen is in circulation in some pockets of the population and that the WWTPs under study do not efficiently remove bacterial pathogens from the wastewater and consequently are threats to public health.

  8. O arquivo e o sonho: a montagem como processo de mediação em “Sem Sol”, de Chris Marker

    Directory of Open Access Journals (Sweden)

    Julia Gonçalves Declie Fagioli

    2015-07-01

    Full Text Available O que propomos, no presente artigo, é pensar a montagem – e, mais especificamente, a montagem de imagens de arquivo – como processo de mediação entre as imagens e o espectador. Para isso, recorremos às ideias de Georges Didi-Huberman para refletir sobre as imagens do sonho e as imagens de arquivo. Ambas – cada uma à sua maneira – carregam vestígios da memória e possuem caráter lacunar. Apenas quando são articuladas no sonho, ou na montagem – no caso do cinema documentário – que se configura um novo sentido. Analisaremos “Sem sol” de Chris Marker, em que as imagens de arquivo são montadas de forma a proporcionar uma reflexão sobre a memória e a história. O filme é construído com imagens de arquivo e leituras de cartas de um cinegrafista viajante, o que confere à narrativa um caráter imaginativo, característica essencial da lembrança e da memória.

  9. Comparison between preoperative biopsy and post-excision histology results in sarcoma: experience at Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa.

    Science.gov (United States)

    Panda, Kitela Ghislain; Hale, Martin J; Kruger, Deirdre; Luvhengo, Thifhelimbilu Emmanuel

    2014-06-06

    Tumour size, grade and subtype are the main prognostic factors in adult patients presenting with soft-tissue sarcoma. Planning for appropriate management, including the need for additional staging investigations and neoadjuvant therapy, is dependent on reliable preoperative histopathological results. To determine whether there is agreement between preoperative and post-excision histological findings in patients presenting with soft-tissue sarcoma, and whether the agreement is influenced by the subtypes of sarcomas. Records of adult patients who had soft-tissue sarcomas excised were reviewed. Kaposi's sarcoma and gastrointestinal stromal tumours were excluded. Data were retrieved from the Department of Anatomical Pathology of the National Health Laboratory Service and theatre records at Chris Hani Baragwanath Academic Hospital, and included patient demography, tumour sites and size, HIV status, biopsy types and post-excision histological findings. Records of 153 patients were found (median age 44 years). The majority of the sarcomas were >5 cm in diameter, deep seated and localised in extremities. The commonest subtype, irrespective of HIV status, was dermatofibrosarcoma protuberans. Fine-needle aspiration biopsy (FNAB) results were inaccurate in determining the malignant nature, grade and subtype of sarcoma. Rates of accurate tumour subtype classification following core needle and incision biopsies when compared with post-excision histological findings were 73.1% and 78.3%, respectively. FNAB should not be used in the primary evaluation of soft-tissue tumours. A report of spindle cells on the FNAB smear should be followed by core needle or incision biopsy. Incision biopsy is superior to core needle biopsy in the classification of sarcomas by subtype.

  10. Meediaterrorist Chris Morris / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2010-01-01

    Briti raadio- ja telesatiirik Christopher Morris ja tema (tele)tegemised seoses kinos Sõprus linastuva islamiäärmuslastest kõneleva komöödiafilmiga "Neli lõvi" (Suurbritannia 2010). Lisaks M. T. "Napid detailid eraelust"

  11. Meediaterrorist Chris Morris / Margit Tõnson

    Index Scriptorium Estoniae

    Tõnson, Margit, 1978-

    2010-01-01

    Briti raadio- ja telesatiirik Christopher Morris ja tema (tele)tegemised seoses kinos Sõprus linastuva islamiäärmuslastest kõneleva komöödiafilmiga "Neli lõvi" (Suurbritannia 2010). Lisaks M. T. "Napid detailid eraelust"

  12. Infantile mitochondrial hepatopathy is a cardinal feature of MEGDEL syndrome (3-methylglutaconic aciduria type IV with sensorineural deafness, encephalopathy and Leigh-like syndrome) caused by novel mutations in SERAC1.

    Science.gov (United States)

    Sarig, Ofer; Goldsher, Dorit; Nousbeck, Janna; Fuchs-Telem, Dana; Cohen-Katsenelson, Ksenya; Iancu, Theodore C; Manov, Irena; Saada, Ann; Sprecher, Eli; Mandel, Hanna

    2013-09-01

    3-Methylglutaconic aciduria (3-MGCA) type IV is defined as a heterogeneous group of inborn errors featuring in common 3-MGCA and associated with primary mitochondrial dysfunction leading to a spectrum of multisystem conditions. We studied four patients who presented at birth with a clinical picture simulating a primary mitochondrial hepatic disorder consistent with the MEGDEL syndrome including 3-MGCA, sensorineural deafness, encephalopathy and a brain magnetic resonance imaging with signs of Leigh disease. All affected children displayed biochemical features consistent with mitochondrial OXPHOS dysfunction including hepatic mitochondrial DNA depletion in one patient. Homozygosity mapping identified a candidate locus on 6q25.2-6q26. Using whole exome sequencing, we identified two novel homozygous mutations in SERAC1 recently reported to harbor mutations in MEGDEL syndrome. Both mutations were found to lead to decreased or absent expression of SERAC1. The present findings indicate that infantile hepatopathy is a cardinal feature of MEGDEL syndrome. We thus propose to rename the disease MEGDHEL syndrome. Copyright © 2013 Wiley Periodicals, Inc.

  13. 深切怀念虫媒病研究专家、《寄生虫与医学昆虫学报》外籍编委Chris Curtis教授

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    国际上久赋盛名的虫媒病研究专家、《寄生虫与医学昆虫学报》外籍编委Chris Curtis教授于2008年5月13时与世长辞。我们痛失一位虫媒病研究大师,追思他在虫媒病遗传防治中首开先河,创造性地灭除蚊虫、力扼疟疾病魔的突出贡献。

  14. 给用户想要的访SolidWorks公司研发副总裁Chris Garcia先生和首席科学家叶修梓博士

    Institute of Scientific and Technical Information of China (English)

    崔晓楠

    2004-01-01

    @@ 从1995年Jon Hirschtck先生领导的团队发布SolidWorks以来,olidWorks在短短不到十年的时间里,从汲汲无名发展成为了国内外市场上用户数最多、用户满意度最高的主流三维CAD系统,这其中有什么秘诀呢?本刊记者就此采房了SolidWorks公司研发副总裁Chris Garcia先生和首席科学家叶修梓博士……

  15. Um estudo observacional do filme Denise está Chamando à luz da teoria de ação de Chris Argyris e Donald Schön Study of the motion picture "Denise Calls Up" focusing on the action theory by Chris Argyris and Donald Schön

    Directory of Open Access Journals (Sweden)

    Nildes R. Pitombo Leite

    2007-01-01

    Full Text Available Este trabalho apresenta uma análise do mundo comportamental retratado no filme Denise está Chamando (Denise Calls Up, de Hal Salwen (1995, cujas características (omissão, distanciamento, manipulação subreptícia, mentiras piedosas, controle e proteção unilaterais são típicas do Oposto ao Modelo I e delicadas para serem identificadas, analisadas e discutidas facilmente nas interações humanas. Esse modelo é oriundo da Teoria de Ação proposta por Chris Argyris e Donald Schön (1977, 1996, aqui utilizados como base de argumentação. Buscou-se, neste trabalho, responder à pergunta de como pesquisadores e consultores podem tornar conhecidos modelos mentais e seus modos de ação. Apresentou-se, ainda, uma perspectiva de análise fílmica, com vistas a contribuir para o incremento de um trabalho científico no Brasil que possa auxiliar grupos e organizações na análise de suas ações. O estudo caracteriza-se como qualitativo, observacional, com base em observação indireta e não-participante. Escolheu-se o método da análise de discurso, baseado em cenas elucidativas da proposição teórica estudada. A fundamentação teórica tentou contextualizar, de modo sucinto, os elementos da Teoria de Ação, identificando, com base no filme, o mundo comportamental que permeia as relações humanas.Behavioral dynamics portrayed in the motion picture, "Denise Calls Up" by Hal Salwen (1955, were analyzed in relation to omission, indifference, surreptitious manipulation, merciful lies and unilateral control and protection. These attitudes are typical of the Opposite of Model I by Chris Argyris and Donald Schön (1995 and are difficult to identify, analyze and discuss in human interactions. Arguments were based on the Model, which was part of their Theory of Action (1977, 1996, and questioned how researchers and consultants could make mental models and modi operandi better known to others. An analysis of the film was also presented thereby

  16. Numerical simulation of a viscoelastic flow through a concentric annular with BSD scheme, influence of the Deborah number; Simulacao numerica do escoamento laminar de fluido viscoelastico PTT (Phan-Thien-Tanner) em tubo anular concentrico - influencia do numero de Deborah

    Energy Technology Data Exchange (ETDEWEB)

    D' Ambros, Alder C.; Vitorassi, Pedro H.; Franco, Admilson T.; Morales, Rigoberto E.M. [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil); Matins, Andre Leibsohn [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES). Tecnologia de Engenharia de Perfuracao

    2008-07-01

    The success of oil well drilling process depends on the correct prediction of the velocities and stresses fields inside the gap between the drill string and the rock formation. Using CFD is possible to predict the behavior of the drilling fluid flow along the annular space, from the bottom to the top of the well. Commonly the drilling fluid is modeled as a Herschel-Bulkley fluid. An alternative is to employ a non-linear viscoelastic model, like the one developed by Phan-Thien-Tanner (PTT). In the present work the PTT constitutive equation is used to model the drilling fluid flow along the annular space. Thus, this work investigates the influence of the Deborah number on the laminar flow pattern through the numerical solution of the equations formed by the coupled velocity-pressure-stress fields. The results are analyzed and validated against the analytical solution for the fully developed annular pipe flow. The relation between the Deborah number (De) and the entry length is investigated, along with the influence of high values of Deborah number on the friction factor, stress and velocity fields. (author)

  17. Muusika ja sotsiaalsed muutused / Kaie Tanner

    Index Scriptorium Estoniae

    Tanner, Kaie, 1975-

    2011-01-01

    26. septembrist 1. novembrini Tallinnas toimunud Rahvusvahelise Muusikanõukogu ülemaailmsel muusikafoorumil räägitust. EMTA prorektor Marje Lohuaru muljetest. Lühiintervjuu Euroopa Muusikanõukogu esimees Timo Klemettineniga

  18. Ideed ja inimesed 2009 / Kaie Tanner

    Index Scriptorium Estoniae

    Tanner, Kaie, 1975-

    2010-01-01

    31. jaanuaril 2009 Estonia kontserdisaalis toimunud aastakontserdil üle antud koorimuusikapreemiatest, koorifestivalist "Tallinn 2009", Hollandis Utrechtis toimunud Euroopa Noortekooride Föderatsiooni Europa Cantat poolt korraldatavast samanimelisest festivalist, Vigalas toimunud muusika seminarlaagrist, Soomes Helsingis toimunud III rahvusvahelisest Harald Anderseni nimelisest kammerkooride konkursist ja üle-eestilisest noorte koorijuhtide konkursist

  19. Ideed ja inimesed 2009 / Kaie Tanner

    Index Scriptorium Estoniae

    Tanner, Kaie, 1975-

    2010-01-01

    31. jaanuaril 2009 Estonia kontserdisaalis toimunud aastakontserdil üle antud koorimuusikapreemiatest, koorifestivalist "Tallinn 2009", Hollandis Utrechtis toimunud Euroopa Noortekooride Föderatsiooni Europa Cantat poolt korraldatavast samanimelisest festivalist, Vigalas toimunud muusika seminarlaagrist, Soomes Helsingis toimunud III rahvusvahelisest Harald Anderseni nimelisest kammerkooride konkursist ja üle-eestilisest noorte koorijuhtide konkursist

  20. Kosovo : kannatlikkusele lootmine pole plaan / Chris Patten

    Index Scriptorium Estoniae

    Patten, Chris

    2007-01-01

    Autor leiab, et arvestades Kosovo elanike ülekaalukat soovi olla vaba Serbiast, riigist, mis üritas nad kõrvaldada, ning alternatiivi täielikku puudumist Belgradi poolt, pole rahvusvahelisel kogukonnal muud võimalust kui anda Kosovole iseseisvus

  1. Kosovo : kannatlikkusele lootmine pole plaan / Chris Patten

    Index Scriptorium Estoniae

    Patten, Chris

    2007-01-01

    Autor leiab, et arvestades Kosovo elanike ülekaalukat soovi olla vaba Serbiast, riigist, mis üritas nad kõrvaldada, ning alternatiivi täielikku puudumist Belgradi poolt, pole rahvusvahelisel kogukonnal muud võimalust kui anda Kosovole iseseisvus

  2. 线粒体DNA G13513A突变所致线粒体脑肌病伴高乳酸血症和脑卒中样发作/Leigh重叠综合征%Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes/Leigh overlap syndrome caused by mutation of mitochondrial DNA G13513A

    Institute of Scientific and Technical Information of China (English)

    韩漫夫; 白润涛; 冯宏业; 陶唯宜; 王朝霞; 袁云

    2009-01-01

    Objective To describe the chnical, neuroimagine, pathological and genetic features in a case with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS)/Leigh overlap syndrome.Methods The ease was a 22-year-old woman with recurrent headache, loss of visual acuity and general seizures over 11 years.MRI demonstrated symmetrical high T2-weighted signals in occipital and parietal lobes, in the late stage of the disease, the above imagine changes on MRJ were also shown in the bilateral basal ganglion and brainstem.She died of status epilepticus at age of 22.Brain autopsy and mitochondrial DNA (mtDNA) analysis were performed in the patient.Results The main neuropathological findings were muhifocal and lamilar spongiform in the cortex of the whole brain, the basal ganglion and middle brain.Gliosis, macrophagie reaction and capillary endothelial proliferation were observed in these areas.All 6 layers of the cortex and subcortical white matter in occipital and parietal lobes were severely affected.GI3513A mutation was found in the gene of mitochondria encoded NADH dehydrogenase subunit 5 (MTNDS).Conclusions MELAS/Leigh overlap syndrome presents the symptoms predominantly affecting the cerebral cortex.Neuroimagines suggested that the lesion initially involves the cerebral cortex and in the late stage implicates the basal ganglion and the brainstem, possibly caused by pathological changes of spongiform with capillary proliferation in these areas.%目的 报道1例线粒体DNA G13513A点突变所致线粒体脑肌病伴高乳酸血症和脑卒中样发作(MELAS)/Leigh重叠综合征的临床、影像学、神经病理学改变特点.方法 患者为22岁女性,反复出现头痛、视力下降和肢体抽动11年,因癫疴持续状态而死亡.之前多次MRI检查发现大脑皮质大片长T1长T2异常信号,病灶从枕叶开始,逐渐波及顶叶,疾病后期累及双侧基底节区及脑干灰质核团.对患者进行脑局部尸体解

  3. “If they don’t see happiness in the picture at least they’ll see the black”: Chris Marker’s Sans Soleil and the Lyotardian Sublime

    Directory of Open Access Journals (Sweden)

    Sarah French

    2010-01-01

    -pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

    Abstract (E: This paper examines Chris Marker’s film Sans Soleil in relation to Jean-François Lyotard’s theory of the sublime. Through an analysis of the film’s representation of memory, time and temporality it will argue that Marker’s film effectively “invokes the unpresentable in presentation itself” (Lyotard, 1992: 15.

     

    Abstract (F: Cet article examine le film Sans Soleil de Chris Marker en relation avec la théorie du sublime de Jean-François Lyotard. À travers une analyse de la représentation de la mémoire, du temps et de la temporalité du film, il soutient que le film de Marker invoque d’une manière effective “l’irreprésentable dans la représentation même” (Lyotard, 1992: 15.

  4. An interesting case of Leigh-like syndrome

    Directory of Open Access Journals (Sweden)

    K Bharani

    2012-01-01

    Full Text Available A 12-year-old female child with motor developmental delay presented with persistent vomiting, recurrent falls and unsteadiness in dark since 2 years of age. There was decline in scholastic performance, bulbar symptoms and aggravation of symptoms during intercurrent illness. Clinically, she had frontal and parietal lobar dysfunction, dysarthria, optic atrophy and LMN VII, IX, X, XII cranial nerve involvement. There was generalized hypotonia, distal muscle wasting, weakness, cerebellar signs and impaired vibration/position sense in distal extremities. Biochemical investigations revealed elevated serum/cerebrospinal fluid (CSF lactate and CSF lactate pyruvate ratio. Neuroimaging demonstrated bilateral symmetrical T2 hyperintensities in basal ganglia, subcortical white matter, cerebellar hemispheres and posterior aspect of spinal cord. As certain atypical features like bilateral symmetrical T2 hyperintensities in subcortical white matter were also seen, metachromatic leukodystrophy was considered in differential diagnosis but ruled out by nerve biopsy. This case is reported for the presence of atypical neuroimaging features that are rarely found in Leigh′s disease.

  5. Alkali based slagging: a case study from Leigh Creek

    Energy Technology Data Exchange (ETDEWEB)

    R.A. Creelman; J. Bamberry; L.A. Juniper; C. Ward [University of Western Sydney, Penrith South, NSW (Australia)

    2003-07-01

    A systematic study was undertaken at NRG Port Augusta Power station in South Australia to determine the cause of ash deposition (slagging) in the boilers. Conventional wisdom suggests that iron in the ash is generally a major player in furnace ash deposition; however, mineralogical and chemical analyses of the deposits showed that the binding phase was plagioclase feldspar, dominated by the sodic feldspar albite. The study resulted in recognition that the cause of the formation of ash deposits in the North Flinders furnaces was the result of the ingestion of sodium and calcium into the melt that bound the deposits. This finding was a breakthrough in understanding the deposition process within these furnaces, and emphasises that not all slagging is iron related and that systematic studies of deposits, coal and ash make fundamental contributions to understanding the ash deposition mechanisms. 9 refs., 5 figs., 2 tabs.

  6. Shostakovich: The Orchestral Songs Vol. 2 / Michael Tanner

    Index Scriptorium Estoniae

    Tanner, Michael

    1996-01-01

    Uuest heliplaadist "Shostakovich: The Orchestral Songs Vol. 2: Six Romances on texts by Japanese poets, Op. 21. Six Poems on Marina Tsvetayeva, Op. 143. Suite on Verses of Michelangelo, Op. 145. Gothenburg Symphony Orchestra, Neeme Järvi". DG 447 085-2GH (71 minutes:DDD)

  7. Shostakovich: The Orchestral Songs Vol. 2 / Michael Tanner

    Index Scriptorium Estoniae

    Tanner, Michael

    1996-01-01

    Uuest heliplaadist "Shostakovich: The Orchestral Songs Vol. 2: Six Romances on texts by Japanese poets, Op. 21. Six Poems on Marina Tsvetayeva, Op. 143. Suite on Verses of Michelangelo, Op. 145. Gothenburg Symphony Orchestra, Neeme Järvi". DG 447 085-2GH (71 minutes:DDD)

  8. Self-Tanners, Tanning Pills, Tanning Booths, and Pregnancy

    Science.gov (United States)

    ... products do not provide protection from the harmful effects of the sun. You should still use sunscreen and protective clothing ... during pregnancy or breastfeeding. Be aware that harmful effects ... including eye damage, liver damage, nausea, cramping, diarrhea, severe itching, ...

  9. AFSC/RACE/SAP/Urban:Tanner Crab Handling Mortality

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Fish and invertebrates that are unintentionally captured during commercial fishing operations and then released back into the ocean suffer mortality at unknown...

  10. Predictors of Sun-Related Behaviors among Young Women: Comparisons between Outdoor Tanners, Fake Tanners, and Tan Avoiders

    Science.gov (United States)

    Day, Ashley K.; Oxlad, Melissa; Roberts, Rachel M.

    2013-01-01

    Objective: Skin cancer incidence continues to rise as a tanned appearance remains desirable, particularly among young women. Fake tanning provides a tanned appearance without exposure to ultraviolet radiation. In order to advance our understanding of the factors that contribute to long-term behavior change, this study explores determinants…

  11. The Baltic Way Out of the Economic Crisis / Chris Viberg

    Index Scriptorium Estoniae

    Viberg, Chris

    2008-01-01

    Majanduslik langus Lätis, Leedus ja Eestis on sarnane Euroopas toimuvaga ning väljendub SKP kasvu aeglustumises, kõrges inflatsioonis ja tööpuuduse kasvus. Vt. samas: Estonia - hope of balanced budget; Lithuania - export will help

  12. It's All about the Money: Chris and Pat Compare Salaries

    Science.gov (United States)

    Renard, Monika K.

    2008-01-01

    Can you name 20 influences on pay that could cause a difference in earnings between two ostensibly equal employees? This short, involving exercise can be used to illustrate the numerous influences that affect how employees' pay is determined, for example, education, experience required for the job, supply and demand, company size, seniority, and…

  13. Response Manual for Combating Spills of Floating Hazardous CHRIS chemicals

    Science.gov (United States)

    1989-01-01

    DISULFIDE ARD No ARSENIC PENTAOXIDE APO No ARSENIC TRICHLORIDE AST No ARSENIC TRIOXIDE ATO No ARSENIC TRISULFIDE ART No ASPHALT ASP Possibly ASPHALT ...BLENDINGS STOCKS: ROOFERS FLUX ARF No ASPHALT BLENDING STOCKS:STRT.RUN RESIDUE ASR No ATRAZINE ATZ No AZINPHOSMETHYL AZM No BARIUM CARBONATE BRC No BARIUM...POLYETHYLENE POLYAMINES PEB No data POLYMETHYLENE POLYPHENYL ISOCYANATE PPI No POLYPHOSPHORIC ACID PPA No POLYPROPYLENE PLP Yes POLYPROPYLENE GLYCOL PGC

  14. It's All about the Money: Chris and Pat Compare Salaries

    Science.gov (United States)

    Renard, Monika K.

    2008-01-01

    Can you name 20 influences on pay that could cause a difference in earnings between two ostensibly equal employees? This short, involving exercise can be used to illustrate the numerous influences that affect how employees' pay is determined, for example, education, experience required for the job, supply and demand, company size, seniority, and…

  15. An Interview with AIDS Vaccine Researcher Chris Parks

    Science.gov (United States)

    Sullivan, Megan

    2010-01-01

    The search for an AIDS (acquired immune deficiency syndrome) vaccine is truly a global effort, with university laboratories, biotech firms, pharmaceutical companies, nonprofit research organizations, hospitals, and clinics all working together to develop an effective vaccine as quickly as possible. The International AIDS Vaccine Initiative (IAVI)…

  16. debating igbo conversion to chris- tianity: a critical indigenous view ...

    African Journals Online (AJOL)

    ment to Christian doctrines accompanied this breadth of nominal change .... challenged Horton's theory as inoperable with regard to the Igbo during the years 1921-1966. ... failed to obtain the rewards promised by acceptance of these radical.

  17. The Baltic Way Out of the Economic Crisis / Chris Viberg

    Index Scriptorium Estoniae

    Viberg, Chris

    2008-01-01

    Majanduslik langus Lätis, Leedus ja Eestis on sarnane Euroopas toimuvaga ning väljendub SKP kasvu aeglustumises, kõrges inflatsioonis ja tööpuuduse kasvus. Vt. samas: Estonia - hope of balanced budget; Lithuania - export will help

  18. International Security. Volume 32, Number 4, Spring 2008. No Sign until the Burst of Fire. Understanding the Pakistan-Afghanistan Frontier

    Science.gov (United States)

    2008-03-01

    geography and typography of the International Security 32:4 42 telligence, The Terrorist Threat to the U.S. Homeland (Washington, D.C.: National...ed. (Oxford: Oxford University Press, 1980). 18. Quoted in Stephen Tanner, Afghanistan: A Military History from Alexander the Great to the Fall of...Olaf Caroe, The Pathans (Oxford: Oxford University , 1958). 21. See Thomas H. Johnson and M. Chris Mason, “Understanding the Taliban and Insurgency in

  19. Mitochondrial depletion causes neonatal-onset leigh syndrome, myopathy, and renal tubulopathy.

    Science.gov (United States)

    Lee, Inn-Chi; Lee, Ni-Chung; Lu, Jang-Jih; Su, Pen-Hua

    2013-03-01

    The authors describe a newborn with postnatal myopathy who subsequently developed feeding difficulties, ophthalmoplegia, ptosis, encephalopathy, and seizures. She became ventilator dependent after sudden apnea. The myopathy was without ragged red fibers in the muscle biopsy. An electron transport chain study showed a markedly generalized low level of enzyme activity, particularly in complexes I, I + III, and IV. An initial electroencephalogram finding was normal; subsequent electroencephalograms showed suppression bursts. The mitochondrial copy number in skeletal muscle was 2% of normal.

  20. AFSC/RACE/SAP/Swiney: Primiparous and multiparous Tanner crab egg extrusion, embryo development and hatching

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This study compares timing of egg extrusion, embryo development, timing and duration of eclosion, and incubation periods of Kodiak, Alaska primiparous and...

  1. Mental Health Problems during Puberty: Tanner Stage-Related Differences in Specific Symptoms. The TRAILS Study

    Science.gov (United States)

    Oldehinkel, Albertine J.; Verhulst, Frank C.; Ormel, Johan

    2011-01-01

    The aim of this study was to investigate associations between specific mental health problems and pubertal stage in (pre)adolescents participating in the Dutch prospective cohort study TRAILS (first assessment: N = 2230, age 11.09 [plus or minus] 0.56, 50.8% girls; second assessment: N = 2149, age 13.56 [plus or minus] 0.53, 51.0% girls). Mental…

  2. Mental health problems during puberty : Tanner stage-related differences in specific symptoms. The TRAILS study

    NARCIS (Netherlands)

    Oldehinkel, Albertine J.; Verhulst, Frank C.; Ormel, Johan

    2011-01-01

    The aim of this study was to investigate associations between specific mental health problems and pubertal stage in (pre)adolescents participating in the Dutch prospective cohort study TRAILS (first assessment: N = 2230, age 11.09 +/- 0.56, 50.8% girls; second assessment: N = 2149, age 13.56 +/- 0.5

  3. Classification of Floating Chris Chemicals for the Development of a Spill Response Manual

    Science.gov (United States)

    1989-01-01

    best sorbents to use on ammonia , concentrated sulfuric acid, sodium hydroxide, potassium cyanide, cadmium chloride, oxalic acid, ethylene diamine...SOVIS o Carbonized sawdust, zeolite F (1-Form), clinoptilolite , polyisobutylene fiber, Dovex XIO, amberlite IRA 402, DE S&L process resin, amberlite...Inoreanics - Silicon Tetrachloride ft E- A’ E- [_ E- C- - Sulfur Trioxide E- A’ E- E- E- E- Inorganics-Cryogens - Ammonia ft C’ A’ C’ C’ E- C’ - Chlorine

  4. Angular sensitivity of vegetation indices derived from CHRIS/PROBA data

    NARCIS (Netherlands)

    Verrelst, J.; Schaepman, M.E.; Kötz, B.; Kneubühler, M.

    2008-01-01

    View angle effects present in spectral vegetation indices can either be regarded as an added source of uncertainty for variable retrieval or as a source of additional information, enhancing the variable retrieval; however, the magnitude of these angular effects remains for most indices unknown or un

  5. Serving the Niche: Viewing Libraries through Chris Anderson's "Long Tail" Lens

    Science.gov (United States)

    Mossman, Katherine

    2006-01-01

    The increasingly famous "Long Tail" is essentially a modernized version of the 80/20 rule, something with which most have at least a passing familiarity. The rule (credited to Vilfredo Pareto, a 19th-century philosopher) hypothesized, for example, that 80 percent of the property in Italy was owned by 20 percent of its citizens. That rule is now…

  6. Computer systems and methods for visualizStolte; Chris ing data

    Science.gov (United States)

    Stolte, Chris; Hanrahan, Patrick

    2013-01-29

    A method for forming a visual plot using a hierarchical structure of a dataset. The dataset comprises a measure and a dimension. The dimension consists of a plurality of levels. The plurality of levels form a dimension hierarchy. The visual plot is constructed based on a specification. A first level from the plurality of levels is represented by a first component of the visual plot. A second level from the plurality of levels is represented by a second component of the visual plot. The dataset is queried to retrieve data in accordance with the specification. The data includes all or a portion of the dimension and all or a portion of the measure. The visual plot is populated with the retrieved data in accordance with the specification.

  7. Soilless culture symposium (special interest for the presentations of Chris Blok and Wim Voogt)

    NARCIS (Netherlands)

    Nichols, M.; Blok, C.; Voogt, W.

    2012-01-01

    The International Symposium on Growing Media and Soilless Cultivation brought together stakeholders from around the world to address the scientific and technological advances in growing media, analytical methods and composting for horticultural uses, focusing on the sustainability of the involved pr

  8. Chris Maker: dos o tres cosas que sé de él

    OpenAIRE

    Álvarez, Mercedes

    2009-01-01

    Retomando los hallazgos narrativos de las vanguardias soviéticas de los años 20, Marker piensa el cine en términos de montaje. Y, como Vertov, concibe este arte como una escritura donde caben el ensayo, el poema visual, el cine- retrato o el documento histórico. Estamos en los años 50, en Francia, cuando una serie de cineastas abren nuevas perspectivas al cine-ensayo, sobre todo a través de cortometrajes. Georges Franju (Le sang de bêtes, 1949) o Alain Resnais (Van Gogh, 1948) participan con ...

  9. Growers throw away money by fertilising on automatic pilot (interview with Chris Blok)

    NARCIS (Netherlands)

    Bezemer, J.; Blok, C.

    2013-01-01

    Growers can fertilise much more precisely and effectively. It’s been proven already that the plant uses fertiliser much more efficiently if the fertiliser system takes into account the measured requirements of the crop. Better utilisation has many benefits: lower emissions into the environment and s

  10. Avaliação qualitativa da pastagem de capim tanner-grass (Brachiaria arrecta, por três diferentes métodos de amostragem Quality evaluation of the tanner grass (Brachiaria arrecta pasture, by three different collection methods

    Directory of Open Access Journals (Sweden)

    Rafael Henrique de Tonissi e Buschinelli de Goes

    2003-02-01

    Full Text Available Objetivou-se avaliar a qualidade da pastagem de Brachiaria arrecta, classificada anteriormente como B. radicans utilizando-se as metodologias da extrusa, pastejo simulado e disponibilidade total. Para a coleta da extrusa, utilizaram-se três novilhos fistulados no esôfago. A disponibilidade total do pasto foi obtida pelo corte rente ao solo, com um quadrado metálico (0,5 x 0,5 m, e o pastejo simulado foi colhido manualmente. Para a digestibilidade in vitro da matéria seca, ocorreu efeito do mês de amostragem, mas não entre as metodologias de coleta utilizadas, em que a extrusa apresentou maiores valores (62,10%. Não ocorreu diferença para os teores de proteína bruta, entre os métodos do pastejo simulado e da extrusa. Os valores de PB para o método de disponibilidade total foram abaixo de 7% e os de FDN (72,3% e FDA (38,2%, encontrados para os três métodos, confirmaram que as forrageiras tropicais são ricas em parede celular. As amostras obtidas pela disponibilidade total não foram representativas da dieta ingerida pelos bovinos. O método de amostragem influiu na determinação da composição química da pastagem. O pastejo simulado pode servir para uma estimativa satisfatória da dieta selecionada por bovinos.The quality of B. radicans, former B. radicans pasture, was evaluated using extrusa collection, hand-plucked and total availability methods. Three esophageous fistulated steers were used for the extrusa collection. Samples for total availability of the pasture were collected cutting plant material close to the ground inside a metalic square (0.5 x 0.5m. hand-plucked method was performed manually. There was a significant effect for the months of collection for the in vitro dry matter disapperance, but not among the collection methods tested. The extrusa collection method showing the highest values (62.1%. There was no difference for crude protein among the simulated grazing and extrusa methods. The CP values for the total availability methods were under 7%. Mean values for the neutral detergent fiber (72.3% and acid detergent fiber (38.2% obtained by the collection methods tested confirmed that tropical forrages have high cell wall contents. The samples obtained by the total availability method did not represent the animals ingesta. The collection method influenced the pasture quality evaluation. The hand-plucked method can be a satisfactory estimated for the diet select by the cattle.

  11. Duncan Tanner Essay Prize 2016: Historical Pageants, Citizenship, and the Performance of Women's History before Second-Wave Feminism.

    Science.gov (United States)

    Thomas, Zoë

    2017-09-01

    This article argues that the early twentieth-century craze for historical pageants provided an opportunity for women's groups to bring a nascent, accessible form of women's history into the lives of local communities across Britain. Mainstream historical pageants were organized across the country, depicting selected episodes from the past usually relating to the local area. However, more than 200 inter-war pageants staged by women's organizations, church groups, and a number of university colleges have not yet been studied. In these pageants, women imaginatively portrayed professional, religious, political, noble, and 'ordinary' women from across history. Prior to second-wave feminism, when scholars advanced the study of women within the academy, thousands of people had been invested in re-enacting women's history since the inter-war years. Emphasizing the bravery and public duties of women in the past, historical pageants provided a non-controversial format through which women's groups could effectively project their beliefs about the role they felt women should play as newly enfranchised citizens. These popular performances capture the dispersed, yet committed, dedication to encouraging women's social citizenship in the inter-war years, and a more pluralistic understanding of women's engagement with 'feminist' ideas in everyday life across Britain. © The Author [2017]. Published by Oxford University Press.

  12. Serbia ja EL : kõigepealt Mladic, siis kõnelused / Chris Patten ; tõlk. Marek Laane

    Index Scriptorium Estoniae

    Patten, Chris

    2007-01-01

    1995. aastal Srebrenica veresauna korraldanud Ratko Mladici vahistamine on üks eeltingimusi Serbiale EL-i stabilisatsioonileppe allakirjutamiseks. Põhjuseks, miks Euroopa Liit püüab loobuda omaenda püstitatud standarditest, on ilmselt Kosovo iseseisvuse küsimus

  13. Duncan Tanner Essay Prize Winner 2014. Against the 'Sacred Cow': NHS Opposition and the Fellowship for Freedom in Medicine, 1948-72.

    Science.gov (United States)

    Seaton, Andrew

    2015-01-01

    This essay recovers organized opposition to the National Health Service (NHS) by considering the Fellowship for Freedom in Medicine (FFM), a conservative organization of doctors who challenged the 'Sacred Cow' of nationalized healthcare in the 1950s and 1960s. While there has been little interest in anti-NHS politics because of shortcomings in the institution's historiography, this study suggests ways a new history of the service can be written. Central to that project is taking the broader ideological and emotive quality of the NHS seriously, and appreciating the way, for all sides of the political spectrum, as well as the general public, the service has always been a contested symbol of post-war British identity. This essay argues that two NHS 'crises'--panics over costs, and disillusionment within general practice--were not merely disagreements over budgets and pay-packets but politically charged moments infused with conservative anxieties over Britain's post-war trajectory. The FFM imagined the NHS as an economically dangerous bureaucratic machine that crushed medical independence and risked pushing the country towards dictatorship. Allies within the Conservative Party, private health insurance industry, and free-market 'think-tanks' worked with the FFM to challenge defences of both the service's operation and meaning. To appreciate why the NHS remains 'the closest thing the English have to a religion', one must consider the apostates as well as the faithful.

  14. [The height target prediction by the Tanner method infra evaluates the final height in youths from the rural area of South East Spain].

    Science.gov (United States)

    Ríos, Rafael; Bosch, Vicente; Santonja, Fernando; López, José Manuel; Garaulet, Marta

    2014-10-16

    Introducción: Conocer la talla final de un individuo antes de finalizar el crecimiento presenta utilidad clínica para el seguimiento de la salud infantil. Objetivo: Calcular la talla diana de una población rural del sudeste de España y comparar con la talla final alcanzada. Métodos: Fueron incluidos 50 jóvenes de 18 a 22 años (44% hombres) y 100 progenitores. La selección de los jóvenes se realizó en 2 fases: 1. Estudio retrospectivo a partir de historias clínicas. 2. Estudio prospectivo: reclutamiento y determinaciones antropométricas. Se calculó talla diana y el desvío de talla. Resultados: La talla final de los chicos fue de 4,44 cm superior a la talla diana (p.

  15. Outcasts Searching for a Place To Fit: A Study of "Frankenstein" by Mary Shelley and "Staying Fat for Sarah Byrnes" by Chris Crutcher.

    Science.gov (United States)

    Martin, Amy

    All people have to deal with feelings of loneliness, isolation, fear, and lack of acceptance, especially in the teenage years. Both of the novels "Staying Fat for Sarah Byrnes" and "Frankenstein" deal with these issues. By 10th grade, students are really searching for who they are and what they want out of life. It is especially important to these…

  16. Growers forget the needs of the crop: More accurate feeding: lower runoff emissions and better use of fertilisers (interview a.o. with Chris Blok)

    NARCIS (Netherlands)

    Bezemer, J.; Blok, C.

    2012-01-01

    Fertilisers received a lot of attention when growers first started using substrates. Since then the nutritional requirements of the plant have been largely driven by the need to reduce runoff emissions. In addition, more efficient use of fertilisers is playing a role. Until now growers went along wi

  17. Free Energy Barrier for Molecular Motions in Bistable [2]Rotaxane Molecular Electronic Devices

    Science.gov (United States)

    2009-04-10

    Org. Chem. 2001, 66, 3559– 3563. (69) Leigh, D. A.; Murphy, A.; Smart, J. P.; Deleuze , M. S.; Zerbetto, F. J. Am. Chem. Soc. 1998, 120, 6458–6467. (70...Leigh, D. A.; Troisi, A.; Zerbetto, F. Chem. Eur. J. 2001, 7, 1450– 1454. (71) Deleuze , M. S.; Leigh, D. A.; Zerbetto, F. J. Am. Chem. Soc. 1999, 121

  18. 76 FR 55736 - Safety Advisory: Unauthorized Marking of Compressed Gas Cylinders

    Science.gov (United States)

    2011-09-08

    ... CONTACT: Chris Michalski, Senior Investigator, Eastern Region, Office of Hazardous Materials Safety Field...-mail: chris.michalski@dot.gov . SUPPLEMENTARY INFORMATION: The Hazardous Materials Regulations...

  19. μ-Oxalato-bis[bis(triphenylphosphinecopper(I] dichloromethane disolvateATR dedicates this paper to the honor of Professor S. Peter Tanner for rekindling a love of inorganic chemistry.

    Directory of Open Access Journals (Sweden)

    Andrew D. Royappa

    2013-02-01

    Full Text Available The dinuclear molecule of the title compound, [Cu2(C2O4(C18H15P4]·2CH2Cl2, lies across an inversion center with a strictly planar bridging oxalate ligand coordinating two CuI ions via two pairs of O atoms. Two triphenylphosphine ligands also coordinate each symmetry-related CuI ion, resulting in a distorted tetrahedral geometry [O—Cu—O = 80.57 (5° and P—Cu—P = 125.72 (2°]. In the crystal, there are two dichloromethane solvent molecules for each dinuclear complex.

  20. Análisis del problema conjugado de transferencia de calor en un microcanal para un flujo electro-ósmotico de un fluido con modelo reológico Phan-Thien Tanner /

    OpenAIRE

    Escandón Colin, Juan Pablo

    2011-01-01

     tesis que para obtener el grado de Doctor en Ingeniería Mecánica, presenta Juan Pablo Escandón Colin ; asesor Oscar Eladio Bautista Godínez. ii, 116 páginas : ilustraciones. Doctorado en Ingeniería Mecánica UNAM, Facultad de Ingeniería, 2011

  1. AFSC/RACE/SAP/Foy: Seawater chemistry of three pH treatments used to test the effect of pH on Tanner crab biology: Kodiak Island, Alaska.

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — To study the effects of ocean acidification we examined the effects of ocean acidification on the embryo and larval stages of the economically important southern...

  2. NPRB 1117 Cooperative research to develop new trawl footrope designs to reduce mortality of southern Tanner and snow crabs (Chionoecetes bairdi and C. opilio) incidental to Bering Sea bottom trawl fisheries

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Alaska’s Bering Sea is home to some of the world’s most productive groundfish and crab stocks and the fisheries that depend on them. Their spatial overlap creates...

  3. Helicopter Icing Spray System (HISS) Evaluation and Improvement

    Science.gov (United States)

    1986-04-01

    spectrometers (models FSSP-100 and OAP-200X), a Leigh MK 10 Ice detector, a Cloud Technology , Inc. LWC sensor, a Rosemount total air temperature probe, and a...dew point hygrometer and display, Leigh Mk 10 ice detector unit with digital display (1984 only), Cloud Technology Inc. model LWH-1 (Johnson Williams...with the probes in place, while photo 2 shows the interior instrumentation rack with displays. 3. The Leigh Mk 10 and Cloud Technology probes were not

  4. Reply to "Comment on 'Falsification Of The Atmospheric CO2 Greenhouse Effects Within The Frame Of Physics' by Joshua B. Halpern, Christopher M. Colose, Chris Ho-Stuart, Joel D. Shore, Arthur P. Smith, J\\"org Zimmermann"

    OpenAIRE

    Gerlich, Gerhard; Tscheuschner, Ralf D.

    2010-01-01

    It is shown that the notorious claim by Halpern et al. recently repeated in their comment that the method, logic, and conclusions of our "Falsification Of The CO2 Greenhouse Effects Within The Frame Of Physics" would be in error has no foundation. Since Halpern et al. communicate our arguments incorrectly, their comment is scientifcally vacuous. In particular, it is not true that we are "trying to apply the Clausius statement of the Second Law of Thermodynamics to only one side of a heat tran...

  5. Science Education and Teacher Effectiveness: Implications of the Next Generation Science Standards (NGSS): Q&A with Chris Wilson, Ph.D., and Jody Bintz, M.S. REL Mid-Atlantic Teacher Effectiveness Webinar Series

    Science.gov (United States)

    Regional Educational Laboratory Mid-Atlantic, 2014

    2014-01-01

    This webinar explored how the Next Generation Science Standards (NGSS) provide an instructional framework to support professional growth and inform teacher evaluation systems for science instruction. This Q&A addressed the questions participants had for Dr. Wilson and Jody Bintz following the webinar. The webinar recording and PowerPoint…

  6. Reply to "Comment on 'Falsification Of The Atmospheric CO2 Greenhouse Effects Within The Frame Of Physics' by Joshua B. Halpern, Christopher M. Colose, Chris Ho-Stuart, Joel D. Shore, Arthur P. Smith, J\\"org Zimmermann"

    CERN Document Server

    Gerlich, Gerhard; 10.1142/S0217979210055573

    2010-01-01

    It is shown that the notorious claim by Halpern et al. recently repeated in their comment that the method, logic, and conclusions of our "Falsification Of The CO2 Greenhouse Effects Within The Frame Of Physics" would be in error has no foundation. Since Halpern et al. communicate our arguments incorrectly, their comment is scientifcally vacuous. In particular, it is not true that we are "trying to apply the Clausius statement of the Second Law of Thermodynamics to only one side of a heat transfer process rather than the entire process" and that we are "systematically ignoring most non-radiative heat flows applicable to Earth's surface and atmosphere". Rather, our falsification paper discusses the violation of fundamental physical and mathematical principles in 14 examples of common pseudo-derivations of fictitious greenhouse effects that are all based on simplistic pictures of radiative transfer and their obscure relation to thermodynamics, including but not limited to those descriptions (a) that define a "Pe...

  7. Summary of Artificial and Natural Icing Tests Conducted on U.S. Army Aircraft from 1974 to 1985

    Science.gov (United States)

    1986-07-01

    and display, Leigh M.K-10 ice detector unit with digital display, Cloud Technology Ice Detector Unit, and a Small Intelligent Icing Data % Systems...display, Cambridge model 137 chilled mirror dew point hygrometer and display, Leigh Mk 10 ice detector unit with digital display, cloud technology ice

  8. Sperm characteristics in a sample of healthy adolescents in São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Marcos Mitsuyoshi Mori

    2002-04-01

    Full Text Available The article presents preliminary data from a prospective investigation in a sample of healthy 14-17-year-old students from a technical school in Sao Paulo, Brazil. Ninety-six Tanner stage 5 and thirty-one Tanner stage 4 adolescents were evaluated: testicular volume was measured using a Prader orchidometer, and semen analysis was performed according to standard procedures. Median testicular volume was 20.0ml among Tanner 5 students and 15.0ml in Tanner 4 students in both the right and left testes. No significant differences were found in sperm volume or motility. Median concentration was 66.0 million/ml for Tanner 5 and 47.0 million/ml for Tanner 4 subjects. Morphological patterns showed abnormal forms in 81.9% of Tanner 5 and 93.6% of Tanner 4 adolescents. Oligospermia (sperm concentration < 5 million/ml was observed in 7.3% of Tanner stage 5 and 12.9% of Tanner stage 4 individuals. Azoospermia was observed in 3 students (1.8%, with counts less than 1.0 in 8 students (4.8%. The authors discuss the observed results, analyzing the potential implications arising from biological development and potential environmental exposures.

  9. Plaadid / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2006-01-01

    Uutest heliplaatidest George Benson "The Essential George Benson", Roy Orbison "The Essential Roy Orbisson", K.D. Lang "Reintaration", Blondie "Greatest Hits", Chris Isaak "Best Of Chris Isaak", Barry Manilov "The Essential Barry Manilow", ABBA "Greatest Hits"

  10. Warpi pidu seekord KUMUs

    Index Scriptorium Estoniae

    2006-01-01

    Briti plaadifirma WarpP teemalisest peost 2. juunil KUMUs minifestivali KUMU ÖÖ raames (auditooriumisaalis linastuvad WarpFilmsi lühifilmid "Warp Vision", Chris Cunninghami "Rubber Johnny" ja Chris Morrise "Mu Wrongs")

  11. 75 FR 65667 - Lincoln Pharmacy; Revocation of Registration

    Science.gov (United States)

    2010-10-26

    ... $975. The prescriptions listed the patients as Chris DiMarco of Clark, NJ; Rudy Lore, also purportedly... and Hsia used three different patient names (Chris DeMarco, Rudy Lore and Paul Smith) on the...

  12. 87 år og stadig en nydelse at læse

    DEFF Research Database (Denmark)

    Bukh, Per Nikolaj

    2010-01-01

    Anmeldelse af Organizational Traps: Leadership, Culture and Organization Design, Chris Argyris, Oxford University Press......Anmeldelse af Organizational Traps: Leadership, Culture and Organization Design, Chris Argyris, Oxford University Press...

  13. Warpi pidu seekord KUMUs

    Index Scriptorium Estoniae

    2006-01-01

    Briti plaadifirma WarpP teemalisest peost 2. juunil KUMUs minifestivali KUMU ÖÖ raames (auditooriumisaalis linastuvad WarpFilmsi lühifilmid "Warp Vision", Chris Cunninghami "Rubber Johnny" ja Chris Morrise "Mu Wrongs")

  14. Plaadid / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2006-01-01

    Uutest heliplaatidest George Benson "The Essential George Benson", Roy Orbison "The Essential Roy Orbisson", K.D. Lang "Reintaration", Blondie "Greatest Hits", Chris Isaak "Best Of Chris Isaak", Barry Manilov "The Essential Barry Manilow", ABBA "Greatest Hits"

  15. To Observe the Clinical Effect of Combination of Leigh Bhave Lin Fever Xingnaojing Injection in the Treatment of Upper Respiratory Tract Infection in Children%利巴韦林结合醒脑静注射液治疗小儿上呼吸道感染伴发热的临床效果观察

    Institute of Scientific and Technical Information of China (English)

    董义文

    2015-01-01

    目的:探讨利巴韦林联合醒脑静治疗小儿上呼吸道感染伴发热的临床效果。方法将我院接受治疗的100例上呼吸道感染伴发热的患儿作为研究对象,将其分为对照组与观察组各50例,对比观察两组患者的临床治疗效果。结果观察组总有效率高达98.00%,明显优于对照组患者的82.00%,P<0.05。结论利巴韦林联合醒脑静注射液治疗方案效果更优。%Objective To investigate the clinical effect with fever ribavirin combined with Xingnaojing Injection in treatment of children with upper respiratory tract infection.MethodsOur hospital treatment of 100 cases with fever and upper respiratory tract infection of children as the research object, Be divided into control group and observation group with 50 cases in each group, the contrast observation of clinical curative effect of two groups of patients.Results The total efifciency was up to 98%, signiifcantly better than the control group of 82% patients,P<0.05.Conclusion Ribavirin combined with Xingnaojing injection treatment better effect.

  16. La influencia de la fotografía cinematográfica en el estilo visual. Análisis del estilo de Dick Pope en las obras cinematográficas del director Mike Leigh: Life is sweet, naked, secrets and lies, career girls, topsy-turvy, all or nothing, vera drake Y happy-go-lucky

    OpenAIRE

    Cortés Selva, Laura

    2012-01-01

    La investigación planteada en este trabajo está fundamentada en un conjunto de inquietudes entre las que se encuentra la necesidad de estrechar los vínculos entre la academia y la profesión. En el terreno de la investigación cinematográfica existe un salto cualitativo entre la teoría y la práctica, una escasa reflexión teórica en torno a una disciplina fundamentalmente basada en la praxis y una praxis en la que apenas existe un pensamiento reflexivo. Fruto de esta inquietud nace la necesidad ...

  17. 1st Baby Born with DNA from 3 Parents

    Science.gov (United States)

    ... women and a man. As reported Tuesday by New Scientist magazine, the technique is designed to help couples ... two children who later died of Leigh syndrome, New Scientist reported. So, the couple turned to a team ...

  18. Matriarhaalne edasikestmine / Jüri Laulik

    Index Scriptorium Estoniae

    Laulik, Jüri, 1959-

    2008-01-01

    12. PÖFFi filmidest: Bernd Böclichi "Kuu ja teised armukesed" ("Der Mond und andere Leibhaber", Saksamaa), Mike Leigh' "Happy-Go-Lucky" (Suurbritannia), Kirill Serebrennikovi "Jüripäev" ("Jurjev den", Venemaa)

  19. Naised mõrvarite jälil / Kaisa Karu

    Index Scriptorium Estoniae

    Karu, Kaisa

    2010-01-01

    Kanal 2 ekraanil kaks naispeaosalistega krimisarja : uurija Lilly Rush (Kathryn Morris) sarjas "Jahtunud jälg" (USA, 2003-... ) ja Brenda Leigh Johnson (Kyra Sedgwick) seriaalis "Vahelevõtja" (USA, 2005-... )

  20. Naised mõrvarite jälil / Kaisa Karu

    Index Scriptorium Estoniae

    Karu, Kaisa

    2010-01-01

    Kanal 2 ekraanil kaks naispeaosalistega krimisarja : uurija Lilly Rush (Kathryn Morris) sarjas "Jahtunud jälg" (USA, 2003-... ) ja Brenda Leigh Johnson (Kyra Sedgwick) seriaalis "Vahelevõtja" (USA, 2005-... )

  1. 75 FR 67697 - Membership of the Performance Review Board

    Science.gov (United States)

    2010-11-03

    ... Pennett Joseph Angello Ronald Pontius Leigh Bradley Susan Yarwood David Fisher Joseph Bonnet III Dennis...Michael Lydia Moschkin Linda Oliver Thomas Milks Matice Wright Alan Shaffer Mark Easton Craig...

  2. Matriarhaalne edasikestmine / Jüri Laulik

    Index Scriptorium Estoniae

    Laulik, Jüri, 1959-

    2008-01-01

    12. PÖFFi filmidest: Bernd Böclichi "Kuu ja teised armukesed" ("Der Mond und andere Leibhaber", Saksamaa), Mike Leigh' "Happy-Go-Lucky" (Suurbritannia), Kirill Serebrennikovi "Jüripäev" ("Jurjev den", Venemaa)

  3. Relationship between Computer Attitudes and Literacy of Science ...

    African Journals Online (AJOL)

    Nekky Umera

    alternative to traditional teaching methods (Leigh, 1996). Actually, computers have ... factors that are instrumental to promoting the use of computer aided learning,. Griffin (1998) found ..... Psychological Review, 84, 191 – 215. Busch, T. (1995).

  4. 75 FR 8923 - Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment...

    Science.gov (United States)

    2010-02-26

    ... industrial weldments. Apple Archery Products LLC 60 Leigh Drive, York, PA 2/17/2010 Apple Archery manufactures 17406. archery repair tools and equipment. Optimax Systems, Inc 6367 Dean Parkway, Ontario,...

  5. Disease: H01368 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 1354]; Kearns-Sayre Syndrome (KSS) [DS:H01355]; Leber Hereditary Optic Neuropathy (LHON) [DS:H00068] Cytochr...r of different clinical phenotypes, including Leigh syndrome, Fatal infantile cardioencephalomyopathy, and Leber

  6. Green Light! A Troop Carrier Squadron’s War from Normandy to the Rhine

    Science.gov (United States)

    1993-01-01

    Britain and the British people. Mother Goose nursery rhymes and unforgettable stories by Sir Walter Scott, Lewis Carroll, and Sir Arthur Conan Doyle were...BEE, one of the invasion training maneuvers back in late May, Arthur Swasey crashed his plane while landing; his ship exploded and burned on the...Marshals, Sir Arthur Tedder, Eisenhower’s Deputy Supreme Commander, and Sir Trafford Leigh-Mallory, also visited. Leigh-Mallory gave us a veddy, veddy

  7. Publications on Borneo from Universiti Malaysia Sarawak, 2001-2002

    OpenAIRE

    Sellato, Bernard

    2013-01-01

    The Institute of East Asian Studies (IEAS) was created at the Universiti Malaysia Sarawak (UNIMAS) in 1998 with Professor Michael Leigh as its inaugural Director. Michael Leigh is a long-time scholar of Sarawak. His earlier publications include: The Chinese Community of Sarawak: a Study of Communal Relations (1964), The Rising Moon: Political Change in Sarawak (1974), and Council Negri Sarawak, Malaysia’s Oldest Legislature (1992). It was after a long career in Australia (University of Sydney...

  8. Anthropometric Measurements, Serum Reproductive Hormonal Levels and Sexual Development among Boys in the Rural Western Cape, South Africa

    Directory of Open Access Journals (Sweden)

    Jun Mao

    2016-11-01

    Full Text Available Data on growth and sexual maturation among boys from the rural Western Cape in South Africa is limited. A cross-sectional study of 269 school boys was conducted testing for serum luteinizing hormone (LH, follicle stimulating hormone (FSH, testosterone, sex hormone binding globulin (SHBG and estradiol (E2; height, weight and body mass index (BMI; sexual maturity (using Tanner Stages and a questionnaire (demographic and medical history. The median age at pubertal onset (Tanner Stage 2 and Tanner Stage 5 was 11.6 and 14.7 years, respectively. The median testicular volume was 5.5 mL at Tanner Stage 2 increasing from 2.5 mL at Tanner Stage 1 to 14.7 mL at Tanner Stage 5. Height and weight measurements were <25th & 50th percentile references at Tanner Stages 1–3. Controlling for confounders, serum FSH and LH increased (p < 0.05 from Tanner Stage 1 to 4 (by 4.1 and 3 mL respectively, and serum testosterone and estradiol increased after Tanner Stage 2 (by 12.7 nmol/L and 59.5 pmol/L respectively. These results indicate some delays in pubertal development of boys in the rural Western Cape when compared to boys from other settings possibly due to nutritional, socio-economic and environmental exposures. Changes in serum hormone levels were consistent with other populations. Initiatives to improve nutrition amongst Western Cape rural communities are recommended.

  9. Andreas Harder, Laut- und Formenlehre der Mundart von Ripatransone, Dis­ sertation zur Erlangung des Doktorgrades der Philosophischen Fakultät der Chris­ tian-Aibrechts- Universität zu Kiel; Kiel 1988, pp. XII + 411 (policopiato.

    Directory of Open Access Journals (Sweden)

    Pavao Tekavčić

    1990-12-01

    Full Text Available La ricchezza dei dialetti italiani non cessa di offrire occasioni sia per scoperte di fatti nuovi che per rielaborazioni di quanto già noto. Fra le curiosità linguistiche davvero uniche non solo in ltalia rna addirittura nella Romània uno dei prirni posti spetta alia penetrazione della categoria del genere in tutto il sistema verbale, che si osserva net dialetto della cittadina di Ripatransone e in minore misura nella vicina Cossignano, al confine delle Marche con gli Abruzzi. La citata curiosità del ripano non è naturalmente passata inosservata finora: infatti, sene sono occupati H. Lüdt­ ke e F. Parrino. Il presente studio di A. Harder è tuttavia_ una trattazione sistemati­ ca, sincronica e diacronica, non soltanto della coniugazione ma, come dice il titolo, anche della fonetica e di tutta Ia morfologia del dialetto della città marchigiana.

  10. A Content Analysis of Google Scholar: Coverage Varies by Discipline and by Database. A review of: Neuhaus, Chris, Ellen Neuhaus, Alan Asher, and Clint Wrede. “The Depth and Breadth of Google Scholar: An Empirical Study.” portal: Libraries and the Academy 6.2 (Apr. 2006: 127‐41.

    Directory of Open Access Journals (Sweden)

    Virginia Wilson

    2007-03-01

    Full Text Available Objective – To ascertain the coverage by discipline, publication date, publication language, and upload frequency of the scholarly articles found in Google Scholar.Design – Comparative content analyses.Setting – Electronic information resources accessible via the internet (both freely accessible and for‐fee databases.Subjects – Forty‐seven online databases and Google Scholar.Methods – The study compared the content of 47 databases (21 Internet resources freely available to the general public; 26 restricted access databases covering a variety of subjects with the content of Google Scholar. Each database was assigned to one of the following discipline categories: business, education, humanities, science and medicine, social science, and multidisciplinary. From April through July 2005, researchers generated random samples of 50 article titles from each of the 47 databases and searched the titles on Google Scholar to determine inclusion. Related studies were conducted for publication date and publication language analysis, and for the Google Scholar upload frequency study. For the publication date study, random samples from one database (PsycINFO with a high degree of variability in Google Scholar coverage were searched for 1990, 2000, and 2004. For the publication language study, Google Scholar coverage of PsycINFO articles in English was compared to coverage of PsycINFO articles published in non‐English languages. For the upload frequency study, two databases chosen for their high degree of coverage (BioMedCentral and PubMed were monitored to determine how often the new content was uploaded to Google Scholar.Main Results – This study revealed that content covered by Google Scholar varies greatly from database to database and from discipline to discipline. Of the 47 databases studied, coverage ranged from 6% to 100%. Mean and median values of coverage for all databases were both 60%. The mean discipline category scores varied from the humanities databases at 10% coverage, to the social sciences and education at 39% and 41% respectively, to science and medicine databases at 76% coverage. Mean coverage was 77% for the multidisciplinary databases. Mean coverage of open access journal databases was 95%, freely accessible databases had 84% mean coverage, and single publisher databases had 83% mean coverage. The publication language study found a bias towards English language publications. As well, a publication date bias was found – coverage of earlier dates was not as thorough as coverage of more recent publications. In the upload frequency study, for BioMed Central and PubMed there appears to be an approximately 15‐week delay in the uploading of new material to Google Scholar.Conclusions – The results of this study serve to alert researchers and information professionals that Google Scholar (in beta test mode at the time of the study has poor coverage in certain areas. To those with access to commercial databases, this serves as a cautionary tale. To those with a dearth of commercial databases, Google Scholar is a welcome site and can provide at least some information. The researchers state that the search engine itself could make future content studies unnecessary if it decides to make its content collection methodology transparent to users. Upload frequency, Google Scholar’s linking services, the advanced search option, and the “cited by” feature could all be subjects of future studies. For its first year in operation, Google Scholar offers a broad range of discipline coverage with substantial depth in some areas. At the time of the study, Google Scholar was working with libraries and vendors to connect search results to library‐licensed fulltext.

  11. Florence Nightingale and the women's movement: friend or foe?

    Science.gov (United States)

    Hektor, L M

    1994-11-01

    The historical analysis of the complex and often contradictory views of Florence Nightingale regarding the rights of women is explored in this paper. Feminism and nursing are often viewed as contradictory and antithetical. The relationship between the two is examined through the link between Florence Nightingale and her contemporary, Barbara Leigh-Smith Bodichon. Leigh-Smith was founder and primary financier of The English Women's Journal that provided a public platform for the major feminist writings of the period. Its offices in Langham Place formed the administrative centre of the Society for Promoting the Employment of Women. Bodichon and her colleagues were often referred to as the 'Langham Place Group'. Unexplored prior to this study was the fact that Leigh-Smith and Nightingale were first cousins. Utilizing techniques of internal and external criticism, primary and secondary sources were surveyed relating to Nightingale and Leigh-Smith. The views of both women on the subjects of the rights of women, women's suffrage, the employment status of women, and the societal place of women are compared and contrasted. The legacy of both Leigh-Smith and Nightingale to twentieth century feminism, the status of women, and the profession of nursing is then elaborated. The exploration of the views of both Nightingale and Leigh-Smith is important to gain a clearer understanding of the existing relationship between nursing and feminism. In keeping with the aims of feminist inquiry, women's experiences, specifically those of Nightingale and Leigh-Smith, are the major 'objects' of investigation. The concluding interpretation provides a synthesis that is emancipatory as well as knowledge generative.

  12. Architectural Survey of Pence Elementary School, Fort Leonard Wood, Missouri

    Science.gov (United States)

    2011-09-01

    School, Cunningham, Tennessee (Sanders)............................ 16 Figure 15. Disney School site plan (Tanner 2006, 16...17 Figure 16. Disney School open classroom (Tanner 2006, 17...heat- ing, toilet facilities , and fire safety created much nicer environments for the students (Graves 1993, 25). Still, schools were basically stacks

  13. Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation

    NARCIS (Netherlands)

    Emons, Joyce; Dutilh, Bas E.; Decker, Eva; Pirzer, Heide; Sticht, Carsten; Gretz, Norbert; Rappold, Gudrun; Cameron, Ewan R.; Neil, James C.; Stein, Gary S.; Wijnen, van Andre J.; Wit, Jan Maarten; Post, Janine N.; Karperien, Marcel

    2011-01-01

    In late puberty, estrogen decelerates bone growth by stimulating growth plate maturation. In this study, we analyzed the mechanism of estrogen action using two pubertal growth plate specimens of one girl at Tanner stage B2 and Tanner stage B3. Histological analysis showed that progression of puberty

  14. Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation.

    NARCIS (Netherlands)

    Emons, J.; Dutilh, B.E.; Decker, E.; Pirzer, H.; Sticht, C.; Gretz, N.; Rappold, G.; Cameron, E.R.; Neil, J.C.; Stein, G.S.; Wijnen, A.J. van; Wit, J.M.; Post, J.N.; Karperien, M.

    2011-01-01

    In late puberty, estrogen decelerates bone growth by stimulating growth plate maturation. In this study, we analyzed the mechanism of estrogen action using two pubertal growth plate specimens of one girl at Tanner stage B2 and Tanner stage B3. Histological analysis showed that progression of puberty

  15. Modeling & Testing of Inflatable Structures for Rapidly Deployable Port Infrastructures

    Science.gov (United States)

    2010-07-01

    Rapidly Deployable Port Infrastructures By: Andrew Bloxom Abel Medellin Chris Vince Dr. Solomon Yim N SW C C D -C IS D -2 01...Andrew Bloxom, Abel Medellin , Chris Vince, Dr. Solomon Yim 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...Andrew Bloxom Abel Medellin Chris Vince Dr. Solomon Yim A special thanks to: • Ben Testerman and Dr. Pat

  16. Wat een biomechanisch model zo spannend maakt

    NARCIS (Netherlands)

    C.J. Snijders (Chris)

    2006-01-01

    textabstractAfscheidscollege Prof.dr.ir. Chris J. Snijders, Hoogleraar Medische Technologie Erasmus Universiteit Rotterdam en Afdelingshoofd Biomedische Natuurkunde en Technologie, Erasmus MC. Uitgesproken 3 november 2006

  17. Impact of pubertal development on endothelial function and arterial elasticity.

    Science.gov (United States)

    Marlatt, Kara L; Steinberger, Julia; Dengel, Donald R; Sinaiko, Alan; Moran, Antoinette; Chow, Lisa S; Steffen, Lyn M; Zhou, Xia; Kelly, Aaron S

    2013-11-01

    Little is known about the relation of pubertal development on endothelial function and arterial elasticity in children and adolescents; therefore, we compared brachial artery flow-mediated dilation and carotid artery elasticity across Tanner (pubertal) stages in children and adolescents. Blood pressure, fasting lipids, glucose and insulin, body fat, insulin sensitivity adjusted for lean body mass, brachial flow-mediated dilation (percent dilation and area under the curve), endothelium-independent dilation (peak dilation and area under the curve), and carotid artery elasticity were evaluated across pubertal stages (Tanner I vs Tanner II-IV vs Tanner V) in 344 children and adolescents (184 males, 160 females; ages 6 to 21 years). One hundred twenty-four subjects (mean age 8.23 ± 0.15 years; 52 females) were Tanner stage I; 105 subjects (mean age 13.19 ± 0.17 years; 47 females) were Tanner stages II-IV; and 115 subjects (mean age 17.19 ± 0.16 years; 61 females) were Tanner stage V. There were no significant differences for any of the measures of vascular structure and function across pubertal stages. Results of the current study indicate that smooth-muscle and endothelial function, as well as carotid artery elasticity, do not differ throughout pubertal development and that accounting for pubertal stage when reporting vascular data in children and adolescents may be unnecessary. Copyright © 2013 Mosby, Inc. All rights reserved.

  18. Metabolic rescue in pluripotent cells from patients with mtDNA disease.

    Science.gov (United States)

    Ma, Hong; Folmes, Clifford D L; Wu, Jun; Morey, Robert; Mora-Castilla, Sergio; Ocampo, Alejandro; Ma, Li; Poulton, Joanna; Wang, Xinjian; Ahmed, Riffat; Kang, Eunju; Lee, Yeonmi; Hayama, Tomonari; Li, Ying; Van Dyken, Crystal; Gutierrez, Nuria Marti; Tippner-Hedges, Rebecca; Koski, Amy; Mitalipov, Nargiz; Amato, Paula; Wolf, Don P; Huang, Taosheng; Terzic, Andre; Laurent, Louise C; Izpisua Belmonte, Juan Carlos; Mitalipov, Shoukhrat

    2015-08-13

    Mitochondria have a major role in energy production via oxidative phosphorylation, which is dependent on the expression of critical genes encoded by mitochondrial (mt)DNA. Mutations in mtDNA can cause fatal or severely debilitating disorders with limited treatment options. Clinical manifestations vary based on mutation type and heteroplasmy (that is, the relative levels of mutant and wild-type mtDNA within each cell). Here we generated genetically corrected pluripotent stem cells (PSCs) from patients with mtDNA disease. Multiple induced pluripotent stem (iPS) cell lines were derived from patients with common heteroplasmic mutations including 3243A>G, causing mitochondrial encephalomyopathy and stroke-like episodes (MELAS), and 8993T>G and 13513G>A, implicated in Leigh syndrome. Isogenic MELAS and Leigh syndrome iPS cell lines were generated containing exclusively wild-type or mutant mtDNA through spontaneous segregation of heteroplasmic mtDNA in proliferating fibroblasts. Furthermore, somatic cell nuclear transfer (SCNT) enabled replacement of mutant mtDNA from homoplasmic 8993T>G fibroblasts to generate corrected Leigh-NT1 PSCs. Although Leigh-NT1 PSCs contained donor oocyte wild-type mtDNA (human haplotype D4a) that differed from Leigh syndrome patient haplotype (F1a) at a total of 47 nucleotide sites, Leigh-NT1 cells displayed transcriptomic profiles similar to those in embryo-derived PSCs carrying wild-type mtDNA, indicative of normal nuclear-to-mitochondrial interactions. Moreover, genetically rescued patient PSCs displayed normal metabolic function compared to impaired oxygen consumption and ATP production observed in mutant cells. We conclude that both reprogramming approaches offer complementary strategies for derivation of PSCs containing exclusively wild-type mtDNA, through spontaneous segregation of heteroplasmic mtDNA in individual iPS cell lines or mitochondrial replacement by SCNT in homoplasmic mtDNA-based disease.

  19. Computational Modeling of Simulation Tests.

    Science.gov (United States)

    1980-06-01

    Mexico , March 1979. 14. Kinney, G. F.,.::. IeiN, .hoce 1h Ir, McMillan, p. 57, 1962. 15. Courant and Friedrichs, ,U: r. on moca an.: Jho...AD 79 275 NEW MEXICO UNIV ALBUGUERGUE ERIC H WANG CIVIL ENGINE-ETC F/6 18/3 COMPUTATIONAL MODELING OF SIMULATION TESTS.(U) JUN 80 6 LEIGH, W CHOWN, B...COMPUTATIONAL MODELING OF SIMULATION TESTS00 0G. Leigh W. Chown B. Harrison Eric H. Wang Civil Engineering Research Facility University of New Mexico

  20. USACE Extreme Sea Levels Advice on Guidance on Procedures to Evaluate and Adapt to Changes in Mean and Extreme Sea Levels.

    Science.gov (United States)

    2014-09-09

    and Natural Resources. ISBN 0 7347 5476 0 Haigh, Ivan D. E. M. S. Wijeratne, Leigh R. MacPherson, Charitha B. Pattiaratchi, Matthew S. Mason, Ryan P...tropical storm surges and mean sea level. Clim Dyn (2014) 42:121–138 DOI 10.1007/s00382-012-1652-1 Haigh, Ivan D., Leigh R. MacPherson, Matthew S...conference on hurricanes and tropical meteorology, 893–896 Harper BA, Stroud SA, McCormack M, West S (2008) A review of historical tropical cyclone

  1. Maailmarändur vaimustus eesti folkloorist / Rein Sikk

    Index Scriptorium Estoniae

    Sikk, Rein, 1961-

    2010-01-01

    Inglise tantsuõpetajast Chris Davisest, kes on käinud Viljandi pärimusmuusika festivalil, meeste rahvatantsupeol Rakveres ja mujal Eestis ning peab eestlasi maailma parimateks vaimuvara hoidjateks. Chris Davis õpetab inglise rahvatantse oma kodumaal ja nüüd ka Eestis ning liitus kaerajaani Euroopasse viimise kampaaniaga

  2. Nigeria: Government Corruption and Electoral Reform

    Science.gov (United States)

    2012-11-02

    charges of 26 Chris Albin -Lackey and Eric Guttschuss, “Corruption on Trial?” Human Rights Watch, August... Albin -Lackey, Chris and Eric Guttschuss. “Corruption on Trial?” Human Rights Watch, August 25, 2011. http://www.hrw.org/print/reports/2011/08/25

  3. Law, Policy and Nonproliferation Project Events and Workshops: Key Themes, Results and Related Materials 2008 - 2009

    Science.gov (United States)

    2010-04-01

    Coast Guard Deborah Berman Monterey Institute James Martin Center for Nonproliferation Studies Chris Bidwell Defense Threat Reduction Agency James...ATTENDEES NAME ORGANIZATION Thomas Appel Booz Allen Hamilton Deborah Berman Monterey Institute for International Studies Chris Bidwell Defense...not credible and that preemptive selfdefense was true ground for action). 108. See generally Harold D. Lasswell & Myres S. McDougal, Jurisprudence

  4. Maailmarändur vaimustus eesti folkloorist / Rein Sikk

    Index Scriptorium Estoniae

    Sikk, Rein, 1961-

    2010-01-01

    Inglise tantsuõpetajast Chris Davisest, kes on käinud Viljandi pärimusmuusika festivalil, meeste rahvatantsupeol Rakveres ja mujal Eestis ning peab eestlasi maailma parimateks vaimuvara hoidjateks. Chris Davis õpetab inglise rahvatantse oma kodumaal ja nüüd ka Eestis ning liitus kaerajaani Euroopasse viimise kampaaniaga

  5. Detection and Elimination of Oncogenic Signaling Networks in Premalignant and Malignant Cells with Magnetic Resonance Imaging

    Science.gov (United States)

    2015-10-01

    work on Projects 2 and 3, and minimized efforts of Drs. Neil Spector and Chris Lascola . We have also added more professional support for project...95-100 melting point NMR data LCMS data comment NMR datafile on Entire sample given to Chris Lascola LCMS datafile yes 162. HS-100143-01 N N N N S N

  6. Detection and Elimination of Oncogenic Signalling Networks in Premalignant and Malignant Cells with Magnetic Resonance Imaging

    Science.gov (United States)

    2015-10-01

    work on Projects 2 and 3, and minimized efforts of Drs. Neil Spector and Chris Lascola . We have also added more professional support for project...95-100 melting point NMR data LCMS data comment NMR datafile on Entire sample given to Chris Lascola LCMS datafile yes 162. HS-100143-01 N N N N S N

  7. Asking "Who Are You?" when Going "into the Wild": Moving beyond an Individualized Form of Outdoor Education

    Science.gov (United States)

    Zink, Robyn

    2010-01-01

    The story of Chris McCandless, as told by Jon Krakauer, and more recently by Sean Penn, tells a familiar tale of going alone into the wilderness in search of the truth of oneself. Chris's story provides a parable to explore some of the motifs that inform contemporary outdoor education. In this paper I draw on the work of Michel Foucault and Judith…

  8. Asking "Who Are You?" when Going "into the Wild": Moving beyond an Individualized Form of Outdoor Education

    Science.gov (United States)

    Zink, Robyn

    2010-01-01

    The story of Chris McCandless, as told by Jon Krakauer, and more recently by Sean Penn, tells a familiar tale of going alone into the wilderness in search of the truth of oneself. Chris's story provides a parable to explore some of the motifs that inform contemporary outdoor education. In this paper I draw on the work of Michel Foucault and Judith…

  9. Thirty-Five Years of School Inspection: Raising Educational Standards for Children with Additional Needs?

    Science.gov (United States)

    Marshall, Chris

    2008-01-01

    In this invited article, Chris Marshall, teacher, educational psychologist, university lecturer, and a former book reviews editor for "BJSE" who has been a leading figure in Her Majesty's Inspectorate, examines the inspection of schools over a period reflecting the 35 years during which "BJSE" has been published. Chris Marshall…

  10. Establishment of Maximum Voluntary Compressive Neck Tolerance Levels

    Science.gov (United States)

    2011-07-01

    Bridges Casey Pirnstill Chris Burneka John Plaga Grant Roush Biosciences and Performance Division Vulnerability Analysis Branch July 2011...S) Michael Cote, John Buhrman, Nathaniel Bridges, Casey Pirnstill, Chris Burneka, John Plaga , Grant Roush 5d. PROJECT NUMBER OSMS 5e. TASK

  11. Shaping the Security Environment Newport paper no. 29

    Science.gov (United States)

    2006-11-29

    cajoling, and writing. First and foremost, Joan Johnson-Freese and Tom Fedyszyn in the National Security Decision Making Department at the U.S. Naval War...Kathleen Mahoney-Norris, Judith Stiehm, Chris Costa , Chris Fettweis, Andy Stigler, Tom Fedyszyn, Mike Morris, and Gene Christy provided important

  12. 75 FR 56485 - Groundfish Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea/Aleutian Islands Crab...

    Science.gov (United States)

    2010-09-16

    ... for Bering Sea/Aleutian Islands King and Tanner Crabs (FMP). The FMP was prepared by the North Pacific... recordkeeping requirements. Dated: September 13, 2010. Eric C. Schwaab, Assistant Administrator for...

  13. 75 FR 48298 - Groundfish Fisheries of the Exclusive Economic Zone Off Alaska; Bering Sea/Aleutian Islands Crab...

    Science.gov (United States)

    2010-08-10

    ... fisheries under the Fishery Management Plan for Bering Sea/Aleutian Islands King and Tanner Crabs (FMP). The...: August 4, 2010. Eric C. Schwaab, Assistant Administrator for Fisheries, National Marine Fisheries...

  14. Physical profile data from CTD casts from the RV Medeia in the coastal waters of Southeast Alaska in support of the SE Alaska Red King Crab Survey from 09 June 2010 to 21 July 2010 (NCEI Accession 0066061)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Alaska Department of Fish and Game conducts annual shellfish surveys that include Red King Crab, Tanner Crab, and Shrimp which is used to manage the personal...

  15. 76 FR 30934 - Combined Notice of Filings #1

    Science.gov (United States)

    2011-05-27

    ...: Montgomery L'Energia Power Partners LP, Tanner Street Generation, LLC. Description: Joint Application for Authorization Under Section203 of the FPA of Montgomery L'Energia Power Partners LP, et. al. Filed Date:...

  16. A general algorithm for distributing information in a graph

    OpenAIRE

    Aji, Srinivas M.; McEliece, Robert J.

    1997-01-01

    We present a general “message-passing” algorithm for distributing information in a graph. This algorithm may help us to understand the approximate correctness of both the Gallager-Tanner-Wiberg algorithm, and the turbo-decoding algorithm.

  17. 78 FR 4142 - Combined Notice of Filings #1

    Science.gov (United States)

    2013-01-18

    ... Sellers Notice of Non-Material Change in Status re: Centennial Wind. Filed Date: 1/9/13. Accession Number..., Tanner Street Generation, LLC. Description: Notice of Non-Material Change in Status of EDF Trading North...

  18. Travelers' Health: International Adoption

    Science.gov (United States)

    ... and condition) Neck: thyroid (enlargement secondary to hypothyroidism, iodine deficiency), lymph nodes Heart: murmurs Chest: symmetry, Tanner stage ... on the child’s country of origin or specific risk factors. These screens may include Chagas disease serologic tests, ...

  19. Army Reserve Military Intelligence: Time for Change

    Science.gov (United States)

    2010-04-20

    Miramax Books, 2002. Goleman , Daniel . Emotional Intelligence. New York: Bantam Books, 1997. Goleman , Daniel , Richard Boyatzis, and Annie McKee...Lieutenant Colonel Neil Anderson, Colonel Marissa Tanner, Mr. Richard Allenbaugh, Colonel (Promotable) Rob Walter, Colonel Jody Daniels , Lieutenant

  20. Evaluation of sexual maturity among adolescent male sickle cell ...

    African Journals Online (AJOL)

    acceptance. Tanner staging assesses pubic hair growth and increase in genital size, the latter factor being best reflected by ..... Research Methodology with Statistics for Health and Social. Sciences. ... observation in one practice. Ann Trop ...

  1. Uut ja vana Tänapäevalt / Krista Kumberg

    Index Scriptorium Estoniae

    Kumberg, Krista

    2003-01-01

    Kirjastuselt "Tänapäev" 2002. a. ilmunud eesti lastekirjandust: Arder, Ott. Metsapoolne : [luuletused]; Tanner, Oskar, pseud. Kati, päkapikk ja Prominent : [jutustus]; Salu, Kristel. Verdi ja Fred, ehk, Sullerite juhtumised : [jutustus

  2. The effect ofethnicity on appendicular bone m.ass in white, coloured ...

    African Journals Online (AJOL)

    weight coloured girls had significantly greater. BMC and ... putatively influence bone mass, namely height, weight, body fat ... ren over the age of 10 years by the Tanner method. 16,17 .... Skinfold thickness does not have a Gaussian distribu-.

  3. Unanswered prayers: religiosity and the god-serving bias.

    Science.gov (United States)

    Riggio, Heidi R; Uhalt, Joshua; Matthies, Brigitte K

    2014-01-01

    Two self-report experiments examined how religiosity affects attributions made for a target person's death. Online adults (Study 1, N = 427) and undergraduate students (Study 2, N = 326) read about Chris who had a heart attack, used religious or health behaviors, and lived or died. Participants made attributions to Chris and God (both studies), and reported their emotions (Study 2). Participants made more attributions to Chris when he lived than when he died, but only when he used health behaviors. The highly religious made more attributions to God, but not when Chris used religious behaviors and died (the God-serving bias); they reported the most positive emotions when Chris lived after using religious behaviors (the Hallelujah effect). Directions for future research in terms of implicit religious beliefs and normative evaluations of religion are discussed.

  4. Changes of ghrelin following oral glucose tolerance test in obese children with insulin resistance

    Institute of Scientific and Technical Information of China (English)

    Xiu-Min Wang; You-Jun Jiang; Li Liang; Li-Zhong Du

    2008-01-01

    AIM: To characterize changes in ghrelin levels in response to oral glucose tolerance test (OGTT) and to correlate changes in ghrelin levels with changes in insulin and glucose following OGTT in Chinese obese children of Tanner I and Ⅱ stage with insulin resistance.METHODS: 22 obese children with insulin resistance state were divided into four groups according to their Tanner stage and gender: boys of Tanner I (BT-Ⅰ), boys of Tanner Ⅱ (BT- Ⅱ), girls of Tanner Ⅰ (GT-Ⅰ), girls of Tanner Ⅱ (GT-Ⅱ). Ghrelin, insulin and glucose were measured at 0, 30, 60 and 120 min following OGTT. The control children with normal BMI were divided into control boys of Tanner I (CBT-Ⅰ, n = 6), control boys of Tanner Ⅱ (CBT- Ⅱ, n = 5), control girls of Tanner I (CGT-1, n = 6), control girls of Tanner II (CGT- Ⅱ, n = 5). Fasting serum ghrelin levels were analyzed.RESULTS: Ghrelin levels were lower in obese groups. Ghrelin levels of control group decreased in Tanner Ⅱ stage (CGT-Ⅰ vs CGT-Ⅱ t = -4.703, P = 0.001; CBT-Ⅰ vs CBT-n t = -4.794, P = 0.001). Basal ghrelin levels in BT- Ⅱ decreased more significantly than that in BT-Ⅰ group (t = 2.547, P = 0.029). Ghrelin levels expressed a downward trend after OGTT among obese children. The decrease in ghrelin levels at 60 min with respect to basal values was 56.9% in BT-Ⅰ. Ghrelin concentrations at 0 min correlated directly with glucose level at 0 min in BT-Ⅰ (r = 0.898, P = 0.015). There wasn't a significant correlation of ghrelin changes with glucose changes and insulin changes during OGTT in obese children with insulin resistance.CONCLUSION: In conclusion, in obese children with insulin resistance, ghrelin levels decreased with advancing pubertal stage. Ghrelin secretion suppression following OGTT was influenced by gender and pubertal stage. Baseline ghrelin levels and ghrelin suppression after OGTT did not significantly correlate with the degree of insulin resistance and insulin sensitivity.

  5. Who are the Millennials?

    Science.gov (United States)

    2010-12-01

    interesting phenomenon associated with this. Once Millennials copy music off the Internet, they typically then go out and buy the CD. When Napster and...are the Millennials ? Leesa Tanner Maritime OR Team DRDC CORA TM 2010-284 December 2010 Who are the Millennials ? Leesa Tanner...chain of command, to the Millennial Generation who are now being recruited into the junior ranks. To better understand this latest generation to

  6. REGULAR LOW-DENSITY PARITY-CHECK CODES BASED ON SHIFTED IDENTITY MATRICES

    Institute of Scientific and Technical Information of China (English)

    He Shanbao; Zhao Chunming; Jiang Ming

    2006-01-01

    This paper extends the class of Low-Density Parity-Check (LDPC) codes that can be constructed from shifted identity matrices. To construct regular LDPC codes, a new method is proposed. Two simple inequations are adopted to avoid the short cycles in Tanner graph, which makes the girth of Tanner graphs at least 8. Because their parity-check matrices are made up of circulant matrices, the new codes are quasi-cyclic codes. They perform well with iterative decoding.

  7. Conventions and nomenclature for double diffusion encoding NMR and MRI

    DEFF Research Database (Denmark)

    Shemesh, Noam; Jespersen, Sune N; Alexander, Daniel C;

    2015-01-01

    Stejskal and Tanner's ingenious pulsed field gradient design from 1965 has made diffusion NMR and MRI the mainstay of most studies seeking to resolve microstructural information in porous systems in general and biological systems in particular. Methods extending beyond Stejskal and Tanner's desig...... to the standard, macroscopic, fractional anisotropy conventionally obtained by diffusion MR. Finally, we discuss future vistas and perspectives for DDE. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc....

  8. Armed Forces Institute of Regenerative Medicine Annual Report 2010

    Science.gov (United States)

    2011-01-01

    ensue. 174 AFIRM Annual Report 2010 our science for their healing Scar Mitigation via Matrix Metalloproteinase-1 Therapy Team Leader(s): Alan ...metric Cell-Laden Hydrogel Capsules. Biomaterials, 30:6896-6902, 2009, PMID: 19800116, NIHMSID147749. Dumas JE, Zienkiewicz K, Tanner SA, Prieto EM...Scaffolds) (PCT/US2009/062621). Filed on October 29, 2009. Dumas JE, Zienkiewicz K, Tanner SA, Prieto EM, Bhattacharyya S, and Guelcher SA (Vanderbilt

  9. Maintaining Wireless Connectivity Constraints for Robot Swarms in the Presence of Obstacles

    Science.gov (United States)

    2011-01-01

    IEEE Transactions on Automatic Control , vol. 51, no...8, pp. 1289–1298, 2006. [11] H. G. Tanner, A. Jadbabaie, and G. J. Pappas, “Flocking in fixed and switching networks,” IEEE Transactions on Automatic Control , vol...swarms,” IEEE Transactions on Automatic Control , vol. 48, no. 4, pp. 692–697, 2003. [20] H. G. Tanner, G. J. Pappas, and V. Kumar, “Leader-to-

  10. [Mitochondrial genome analysis in the probands of six Chinese families with MELAS].

    Science.gov (United States)

    Liu, Li; Yuquan, Shao; Baorong, Zhang; Pingping, Jiang; Ailian, Du; Minxin, Guan

    2014-11-01

    Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS) is a genetically heterogeneous disorder. The most prevalent mitochondrial DNA (mtDNA) mutation associated with MELAS is the m.3243A>G transition in the mitochondrial tRNA(Leu(UUR)) gene. Here, we report the clinical, genetic and molecular characterization of six probands from Han Chinese families with MELAS. Four of six probands carried the heteroplasmic m.3243A>G mutation. The levels of mutation load ranged from 29% to 59%, which were correlated with the severity of the clinical phenotypes. Two probands with MELAS/Leigh overlap were 3243 A>G negative, whose severity and relapse were greater than the other 4 probands. One proband with MELAS/Leigh harbored the known ND5 m.13094T>C mutation, which is related to MELAS/Leigh overlap and cerebella ataxia. Sequence analysis of entire mtDNA showed the distinct sets of variants including some variants that may be associated with diabetes, hearing loss, seizures, cardiomyopathy, and Leigh syndrome. Our data suggested that the phenotype and severity of MELAS mainly depend on the mutation load, and some variants may partially contribute to the phenotype and diversity. Our finding also highlighted the complexity of the relationship between genotype and phenotype in MELAS.

  11. Identity Development and Mentoring in Doctoral Education

    Science.gov (United States)

    Hall, Leigh A.; Burns, Leslie D.

    2009-01-01

    In this essay, Leigh Hall and Leslie Burns use theories of identity to understand mentoring relationships between faculty members and doctoral students who are being prepared as educational researchers. They suggest that becoming a professional researcher requires students to negotiate new identities and reconceptualize themselves both as people…

  12. Mutations in C12orf65 in patients with encephalomyopathy and a mitochondrial translation defect.

    NARCIS (Netherlands)

    Antonicka, H.; Ostergaard, E.; Sasarman, F.; Weraarpachai, W.; Wibrand, F.; Pedersen, A.M.; Rodenburg, R.J.T.; Knaap, M.S. van der; Smeitink, J.A.M.; Chrzanowska-Lightowlers, Z.M.; Shoubridge, E.A.

    2010-01-01

    We investigated the genetic basis for a global and uniform decrease in mitochondrial translation in fibroblasts from patients in two unrelated pedigrees who developed Leigh syndrome, optic atrophy, and ophthalmoplegia. Analysis of the assembly of the oxidative phosphorylation complexes showed severe

  13. Disease: H00155 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available s SE, Norbury G, Leigh S, Hadfield SG, Nair D What is the clinical utility of DNA testing in patients with f...wson AJ, Humphries SE Cascade testing in familial hypercholesterolaemia: how should family members be contac...ted? Eur J Hum Genet 13:401-8 (2005) PMID:15990592 Hadfield SG, Humphries SE Implementation of cascade testing

  14. Parenting a Precocious Preschooler: Breaking the Silence

    Science.gov (United States)

    Fish, Leigh Ann

    2016-01-01

    Precocity in the very young should be a valid topic of discussion in parental and educational circles, yet too frequently those conversations are slow to occur or are absent altogether. Many parents and educators remain silent about raising and nurturing precocious preschoolers, and author Leigh Ann Fish believe that the silence is due to a lack…

  15. Supermodellid läbi aegade / Kaarin Kivirähk

    Index Scriptorium Estoniae

    Kivirähk, Kaarin

    2014-01-01

    20. sajandi supermodellid: Anita Colby, Lisa Fonssagrives, Dorian Leigh, Suzy Parker, Dovima, Jean Shrimpton, Twiggy, Jerry Hall, Iman, Lauren Hutton, Marisa Berenson, Janice Dickinson, Cindy Crafword, Paulina Porizkova, Gia Carangi, Elle Macpherson, Linda Evangelista, Naomi Campbell, Gisele Bündchen, Kate Moss, Carmen Kass

  16. Skeletal muscle mitochondria of NDUFS4(-/-) mice display normal maximal pyruvate oxidation and ATP production

    NARCIS (Netherlands)

    Alam, M.T.; Manjeri, G.R.; Rodenburg, R.J.T.; Smeitink, J.A.M.; Notebaart, R.A.; Huijnen, M.A.; Willems, P.H.G.M.; Koopman, W.J.H.

    2015-01-01

    Mitochondrial ATP production is mediated by the oxidative phosphorylation (OXPHOS) system, which consists of four multi-subunit complexes (CI-CIV) and the FoF1-ATP synthase (CV). Mitochondrial disorders including Leigh Syndrome often involve CI dysfunction, the pathophysiological consequences of whi

  17. Kuu filmid / toimetanud Maria Ulfsak-Šeripova

    Index Scriptorium Estoniae

    2011-01-01

    Aki Kaurismäki film "Le Havre" (Soome-Prantsusmaa-Saksamaa 2011) kinos Sõprus, Julia Leigh debüütfilm "Uinuv kaunitar" Coca-Cola Plazas (Austraalia 2011) ja režissöör Cyril Tuschi dokumentaalfilm "Hodorkovski" (Saksamaa 2011) Artise kinos

  18. Exploring Gender Norms through the "Colour Blind" Initiative

    Science.gov (United States)

    Niblett, Blair; Potvin, Leigh

    2010-01-01

    Recently, the authors have been collecting data for a research project that explores secondary school boys' perceptions of masculinity. They spent a week in Leigh's grade 11 philosophy class discussing gender while observing and video recording students' perception for analysis. In their research, they used Colour Blind as a vehicle for unearthing…

  19. High Explosive Simulation of a Nuclear Surface Burst. A Feasibility Study

    Science.gov (United States)

    1979-06-30

    of Defense Deputy Chief of Staff for Ops. & Plans Atomic Energy Department of the Army ATTN: Executive Assistant ATTN: MOCA -ADL Defense Advanced Rsch...Newmark ATTN: K. Kreyenhagen ATTN: Library University . New Mexico ATTN: M. Rosenblatt ATTN: CERF, G. Leigh ATTN: S. Shuster ATTN: CERF, N. Daum

  20. Feasibility Investigation of a Permanent Fuel-Air Explosive Blast Simulator.

    Science.gov (United States)

    1978-08-09

    8440, G. O’Hara ATTN: Code 2627 Deputy Chief of Staff for Ops. & Plans Department of the Army Naval Sea Systems Command ATTN: MOCA -ADL ATTN: SEA...New Mexico ATTN: G. Abrahamson ATTN: CERF, G. Leigh ATTN: B. Gasten ATTN: CERF, N. Baum Systems, Science & Software, Inc. Pacifica Technology ATTN

  1. Supermodellid läbi aegade / Kaarin Kivirähk

    Index Scriptorium Estoniae

    Kivirähk, Kaarin

    2014-01-01

    20. sajandi supermodellid: Anita Colby, Lisa Fonssagrives, Dorian Leigh, Suzy Parker, Dovima, Jean Shrimpton, Twiggy, Jerry Hall, Iman, Lauren Hutton, Marisa Berenson, Janice Dickinson, Cindy Crafword, Paulina Porizkova, Gia Carangi, Elle Macpherson, Linda Evangelista, Naomi Campbell, Gisele Bündchen, Kate Moss, Carmen Kass

  2. Mutations in the phospholipid remodeling gene SERAC1 impair mitochondrial function and intracellular cholesterol trafficking and cause dystonia and deafness.

    NARCIS (Netherlands)

    Wortmann, S.B.; Vaz, F.M.; Gardeitchik, T.; Vissers, L.E.L.M.; Renkema, G.H.; Schuurs-Hoeijmakers, J.H.M.; Kulik, W.; Lammens, M.M.Y.; Christin, C.; Kluijtmans, L.A.J.; Rodenburg, R.J.T.; Nijtmans, L.G.J.; Grunewald, A.; Klein, C.; Gerhold, J.M.; Kozicz, T.L.; Hasselt, P.M. van; Harakalova, M.; Kloosterman, W.; Baric, I.; Pronicka, E.; Ucar, S.K.; Naess, K.; Singhal, K.K.; Krumina, Z.; Gilissen, C.F.H.A.; Bokhoven, J.H.L.M. van; Veltman, J.A.; Smeitink, J.A.M.; Lefeber, D.J.; Spelbrink, J.N.; Wevers, R.A.; Morava, E.; Brouwer, A.P.M. de

    2012-01-01

    Using exome sequencing, we identify SERAC1 mutations as the cause of MEGDEL syndrome, a recessive disorder of dystonia and deafness with Leigh-like syndrome, impaired oxidative phosphorylation and 3-methylglutaconic aciduria. We localized SERAC1 at the interface between the mitochondria and the endo

  3. Eyes on MEGDEL: Distinctive Basal Ganglia Involvement in Dystonia Deafness Syndrome

    NARCIS (Netherlands)

    Wortmann, S.B.; Hasselt, P.M. van; Baric, I.; Burlina, A.; Darin, N.; Horster, F.; Coker, M.; Ucar, S. Kalkan; Krumina, Z.; Naess, K.; Ngu, L.H.; Pronicka, E.; Riordan, G.; Santer, R.; Wassmer, E.; Zschocke, J.; Schiff, M.; Meirleir, L. de; Alowain, M.A.; Smeitink, J.A.M.; Morava, E.; Kozicz, L.T.; Wevers, R.A.; Wolf, N.I.; Willemsen, M.A.

    2015-01-01

    Pediatric movement disorders are still a diagnostic challenge, as many patients remain without a (genetic) diagnosis. Magnetic resonance imaging (MRI) pattern recognition can lead to the diagnosis. MEGDEL syndrome (3-MethylGlutaconic aciduria, Deafness, Encephalopathy, Leigh-like syndrome MIM #61473

  4. Biotin deficiency in the rat as a model for reduced pyruvate carboxylase activity

    NARCIS (Netherlands)

    Schrijver, Jacobus

    1978-01-01

    The investigations described in this thesis are a contribution to the study of Leigh's disease (Subacute Necrotizing Encephalomyelopathy, SNE). SNE resembles in neuropathology Wernicke's encephalopathy, which is caused by thiamine deficiency. The scope and the purpose of the present study is given i

  5. An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase

    NARCIS (Netherlands)

    Hinttala, R.; Sasarman, F.; Nishimura, T.; Antonicka, H.; Brunel-Guitton, C.; Schwartzentruber, J.; Fahiminiya, S.; Majewski, J.; Faubert, D.; Ostergaard, E.; Smeitink, J.; Shoubridge, E.A.

    2015-01-01

    Protein synthesis in mitochondria is initiated by formylmethionyl-tRNA(Met) (fMet-tRNA(Met)), which requires the activity of the enzyme MTFMT to formylate the methionyl group. We investigated the molecular consequences of mutations in MTFMT in patients with Leigh syndrome or cardiomyopathy. All

  6. Universal Physical Fitness Testing for United States Guardians Afloat

    Science.gov (United States)

    2016-06-10

    Coast Guard. v ACKNOWLEDGMENTS Although this may sound cliché to the reader, foremost I honestly must thank God. I thank Ginger, my spouse, for...2 Figure 2. NVivo Visual ...6 Paulo M. Alves, Robb Leigh, Ginger Bartos, Rita Mody, Linda Gholson, and Neil Nerwich

  7. An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase

    DEFF Research Database (Denmark)

    Hinttala, Reetta; Sasarman, Florin; Nishimura, Tamiko;

    2015-01-01

    Protein synthesis in mitochondria is initiated by formylmethionyl-tRNA(Met) (fMet-tRNA(Met)), which requires the activity of the enzyme MTFMT to formylate the methionyl group. We investigated the molecular consequences of mutations in MTFMT in patients with Leigh syndrome or cardiomyopathy. All p...

  8. 78 FR 5837 - Cancellation of Environmental Impact Statement/Environmental Impact Report on the Sacramento...

    Science.gov (United States)

    2013-01-28

    ... Bureau of Reclamation Cancellation of Environmental Impact Statement/Environmental Impact Report on the... plans to continue work on a joint environmental impact statement/environmental impact report (EIS/EIR... (68 FR 44811). Dated: December 11, 2012. Anastasia T. Leigh, Regional Environmental Officer,...

  9. Berlinale art-house'i killukesi / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2008-01-01

    Berliini 58. filmifestivali filmidest : USA režissööri Errol Morrise dokfilm "Tavaprotseduur" ("Standard Operating Procedure"), mehhiklase Fernando Eimbcke mängufilm "Tahoe järv" ("Lake Tahoe"), aserbaidžaani päritolu vene režissööri Anna Melikjani "Merineitsi" ("Russalka") ja inglase Mike Leigh' "Muretu" ("Happy-Go-Lucky")

  10. The Right Time: Building the Learning Community Movement

    Science.gov (United States)

    Mutnick, Deborah

    2015-01-01

    The author argues that the current conjuncture is a kairotic moment for their own learning community program as well as the national movement to support the development of learning communities in universities and colleges and the array of pedagogical approaches associated with them. With Barbara Leigh Smith (2013), they recognize a link between…

  11. Gender, the City and the Politics of Schooling: Towards a Collective Biography of Women "Doing Good" as Public Moralists in Victorian London

    Science.gov (United States)

    Martin, Jane

    2005-01-01

    This article tells the stories of four middle class, white, English women whose participation in educational policy making is little known: Annie Leigh Browne (1851-1936), Margaret MacDonald (1870-1911), Hilda Miall-Smith (born 1861) and Honnor Morten (1861-1913). In doing so, it provides a perspective on the circumstances that enabled or…

  12. The Impact of Maternal Deafness on Cradling Laterality with Deaf and Hearing Infants

    Science.gov (United States)

    Sieratzki, Jechil S.; Woll, Bencie

    2004-01-01

    A recent article in the "Journal of Deaf Studies and Deaf Education" (Leigh, Brice, & Meadow-Orlans, 2004) explored attachment between deaf mothers and their 18-month-old children and reported relationship patterns similar to those for hearing dyads. The study reported here explores a marker of early mother-child relationships: cradling…

  13. Mellow Mélange: Marge and Blanche

    DEFF Research Database (Denmark)

    Elias, Camelia

    2010-01-01

    , beautifully portrayed by Vivien Leigh, or is it a story about culture clashes embodied by a dashing Marlon Brando? But this was the question then. My paper will juxtapose the 50s melodrama with a pastiche of the Streetcar Named Desire and look at how The Simpsons version of the play, the episode A Streetcar...

  14. MMI (Michigan Molecular Institute) International Symposium on Polymer Melt Dynamics (18th) Held in Midland, Michigan on August 16-19, 1987

    Science.gov (United States)

    1987-08-19

    Molecular Institute Cornell University Midland, MI 48640 Ithaca, Nr 14853 Leigh G. Baxandall Chuck C. Crabb Cavendish Laboratory Rohm & Haas Research Lab...Macromolecules 20(1987) 679. --- 8 DYNAMICS OF REVERSIBLY CROSSLINKED CHAINS L.G. Baxandall , Cavendish Laboratory, Cambridge The dynamics and linear

  15. Kas Graali veri võtab võimu Euroopas? / Jaakko Hallas

    Index Scriptorium Estoniae

    Hallas, Jaakko

    2002-01-01

    Templirüütlite saladustest ja Jeesuse järglastest. Martin Baueri raamatust "Templirüütlid. Müüt ja tõde" : Tartu, 2001 ja Michael Baigenti, Richard Leigh', Henry Lincolni raamatust "Püha veri ja Püha Graal" : Tallinn, 2001

  16. Berlinale art-house'i killukesi / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2008-01-01

    Berliini 58. filmifestivali filmidest : USA režissööri Errol Morrise dokfilm "Tavaprotseduur" ("Standard Operating Procedure"), mehhiklase Fernando Eimbcke mängufilm "Tahoe järv" ("Lake Tahoe"), aserbaidžaani päritolu vene režissööri Anna Melikjani "Merineitsi" ("Russalka") ja inglase Mike Leigh' "Muretu" ("Happy-Go-Lucky")

  17. Med skuespilleren på arbejde

    DEFF Research Database (Denmark)

    Thygesen, Mads

    2010-01-01

    for Konstantin Stanislavskijs, Michael Chekhovs og Mike Leighs arbejde med skuespilleren. I anden del, ”Den dramaturgiske proces”, handler det om Bertolt Brecht, Sanford Meisner og Jacques Lecoq. I tredje del handler det om ”Den konceptuelle proces” hos Edward Gordon Craig, Vselovod Mejerhold og Eugenio Barba...

  18. Filmimaailma aplaus realismile : kolmas festivalikiri Cannes'ist, kus filmiprogramm on ületanud ekvaatori / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2002-01-01

    Kolmest seni huvitavamast filmist : inglase Mike Leigh' "Kõik või ei midagi", Michiganist pärit dokumentalisti Michael Moore'i ameeriklaste vägivaldsust uuriv "Keeglimäng enne Columbine'i", iraanlase Abbas Kiarostami "10" ja Kanada armeenlase Atom Egoyani "Ararat"

  19. Filmimaailma aplaus realismile : kolmas festivalikiri Cannes'ist, kus filmiprogramm on ületanud ekvaatori / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2002-01-01

    Kolmest seni huvitavamast filmist : inglase Mike Leigh' "Kõik või ei midagi", Michiganist pärit dokumentalisti Michael Moore'i ameeriklaste vägivaldsust uuriv "Keeglimäng enne Columbine'i", iraanlase Abbas Kiarostami "10" ja Kanada armeenlase Atom Egoyani "Ararat"

  20. An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase

    NARCIS (Netherlands)

    Hinttala, R.; Sasarman, F.; Nishimura, T.; Antonicka, H.; Brunel-Guitton, C.; Schwartzentruber, J.; Fahiminiya, S.; Majewski, J.; Faubert, D.; Ostergaard, E.; Smeitink, J.; Shoubridge, E.A.

    2015-01-01

    Protein synthesis in mitochondria is initiated by formylmethionyl-tRNA(Met) (fMet-tRNA(Met)), which requires the activity of the enzyme MTFMT to formylate the methionyl group. We investigated the molecular consequences of mutations in MTFMT in patients with Leigh syndrome or cardiomyopathy. All pati

  1. Effects of Bright Light Therapy on Sleep, Cognition, Brain Function, and Neurochemistry in Mild Traumatic Brain Injury

    Science.gov (United States)

    2015-01-01

    experienced after head injury and its reliability Journal of Neurology, 242, 587-592. Potter , S., Leigh, E., Wade, D., Fleminger, S. (2006). The...Marshall NS, Harris RB, Reid P (2005) Sleep, sleepiness and motor vehicle accidents: a national survey. Aust N Z J Public Health 29: 16-21. 6. Penetar D

  2. Evaluation of Innate Immune Biomarkers in Saliva for Diagnostic Potential of Bacterial and Viral Respiratory Infection

    Science.gov (United States)

    2014-02-03

    newly cloned DNA probe. Digestive diseases and sciences 43:1211-1218. 20. Leigh JE, Steele C, Wormley FL, Jr., Luo W, Clark RA, Gallaher W, Fidel...Zhou M, Chen Q. 2008. NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population

  3. Anthropometric Measurements, Serum Reproductive Hormonal Levels and Sexual Development among Boys in the Rural Western Cape, South Africa.

    Science.gov (United States)

    Mao, Jun; Dalvie, Mohamed Aqiel

    2016-11-29

    Data on growth and sexual maturation among boys from the rural Western Cape in South Africa is limited. A cross-sectional study of 269 school boys was conducted testing for serum luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone, sex hormone binding globulin (SHBG) and estradiol (E2); height, weight and body mass index (BMI); sexual maturity (using Tanner Stages) and a questionnaire (demographic and medical history). The median age at pubertal onset (Tanner Stage 2) and Tanner Stage 5 was 11.6 and 14.7 years, respectively. The median testicular volume was 5.5 mL at Tanner Stage 2 increasing from 2.5 mL at Tanner Stage 1 to 14.7 mL at Tanner Stage 5. Height and weight measurements were development of boys in the rural Western Cape when compared to boys from other settings possibly due to nutritional, socio-economic and environmental exposures. Changes in serum hormone levels were consistent with other populations. Initiatives to improve nutrition amongst Western Cape rural communities are recommended.

  4. Puitpilvelõhkuja on valmis!

    Index Scriptorium Estoniae

    2008-01-01

    Üheksakorruseline ristkihtpuitpaneelidest korterelamu Londonis. Arhitektid: Sophie Goldhill, Chris Gray, Kristen Haggart, Andrew Waugh arhitektuuribüroost Waugh Thistleton. Konstruktorid: Megan Yates, Matthew Linegar, Bruno Dujič. Ristlamineeritud puitpaneelid valmistas Austria firma KLH

  5. 77 FR 66084 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2012-11-01

    ... CAMPBELL JESSICA ANNE CHANG WAYNE WEN TIEN CHAN-PALAY VICTORIA LYE-HUA CHEN HOPE MI CHENG ANTHONY ENRIQUE... KARIN LUCIENNE WALKER JANICE LOUISE THEDA WALLEY JOHN FRANKLIN WARREN DANIEL THOMAS WATLER CHRIS- WESLEY...

  6. Väike tõlkeraamatu-rehnut / Kalev Kesküla, Ilvi Liive

    Index Scriptorium Estoniae

    Kesküla, Kalev, 1959-2010

    2005-01-01

    18.-22. mail toimus Käsmu loomemajas eesti kirjanduse muudesse keeltesse tõlkijate seminar. Sisaldab nimekirja "Eesti kirjandus inglise keeles" [2003-2006]. Tõlkijad Eric Dickens, Fiona Sampson, Chris Moseley, Christopher Maclehose, Vera Ruber, Vishnu Khare

  7. Harry Potteri seiklused jõuavad kinolinale / Neeme Korv, Neeme Raud

    Index Scriptorium Estoniae

    Korv, Neeme, 1974-

    2001-01-01

    Homme on Londonis Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseeringu esilinastus. Selle 125 miljonit dollarit maksnud USA filmi režissöör on Chris Columbus ja peaosas 12-aastane Daniel Radcliff

  8. Harry, kes vallutab maailma / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2001-01-01

    Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseeringu esilinastus Eestis on 21. detsembril Coca-Cola Plazas. Selle USA filmi režissöör on Chris Columbus ja peaosas 12-aastane Daniel Radcliffe

  9. Garri Potter i filosofski kamen

    Index Scriptorium Estoniae

    2001-01-01

    4. novembril oli Londonis Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseeringu esilinastus. Selle 125 miljonit dollarit maksnud USA filmi režissöör on Chris Columbus ja peaosas 12-aastane Daniel Radcliff

  10. Praktitsheskoje proizvodstvo Sveta i Magii / Olga Marsheva

    Index Scriptorium Estoniae

    Marsheva, Olga

    2002-01-01

    Veel fakte režissöör Chris Columbuse Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ("Harry Potter and the Sorcerer's Stone") järgi tehtud ekraniseeringust : Ameerika Ühendriigid 2001

  11. Euro-Atlandi telg püsib / Ilmar Mikiver

    Index Scriptorium Estoniae

    Mikiver, Ilmar, 1920-2010

    2004-01-01

    Euroopa Liidu ja NATO koostöö USA-ga terrorivastases võitluses on paremaks muutunud, sellest annab tunnistust Euroopa Komitee esimehe Romano Prodi ja Euroliidu välisasjade peavoliniku Chris Patteni ühisdeklaratsioon Euroopa kaasvastutusest

  12. Biopolitik, Hybridität und Fremdartigkeit im US-amerikanischen Superheldenfilm

    Directory of Open Access Journals (Sweden)

    Chris Boge

    2012-06-01

    Full Text Available Chris Boge analysiert in seinem Beitrag, wie biopolitische Diskurse die Narrationen in Blockbustern strukturieren, in denen Superhelden juristische oder biotechnologische Konstellationen aushandeln und dabei Problemlagen sichtbar werden, die auch in unserem Alltag wiederkehren.

  13. Podcast: The Electronic Crimes Division

    Science.gov (United States)

    Sept 26, 2016. Chris Lukas, the Special Agent in Charge of the Electronic Crimes Division within the OIG's Office of Investigations talks about computer forensics, cybercrime in the EPA and his division's role in criminal investigations.

  14. Sticking with One Doctor May Help Keep Seniors Out of the Hospital

    Science.gov (United States)

    ... a senior research associate, and Chris Salisbury, a professor of primary health care. Not only would it benefit patients, it would improve doctors' job satisfaction and likely reduce pressure on hospitals, they ...

  15. Plaadid / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2002-01-01

    Uutest plaatidest David Guetta "Just A Little More Love", Bond "Shine", Chris de Burgh "Timing Is Everything...", Diana Krall "Live In Paris", Richard Ascroft "Human Conditions", Rein Laaneorg "Teine elu", Leaves "Breathe", Derek Trucks Band "Jouful Noise"

  16. Plaadid / Mari Peegel

    Index Scriptorium Estoniae

    Peegel, Mari, 1978-

    2005-01-01

    Uutest heliplaatidest Neil Tennant/Chris Lowe "Battleship Potemkin", Institute "Distort Yourself", Bob Dylan "No Direction Home", Jem "Finally Woken", Machine Men "Elegies", Jamie Cullum "Catching Tales", Bloodhound Gang "Hefty Fine"

  17. Stemcell Information: SKIP000846 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available tt A. Noggle ... Scott A. Noggle ... The New York Stem Cell Foundation Research Institute...dard ... Chris M. Woodard ... The New York Stem Cell Foundation Research Institute The New York Stem Cell Foundation Research Institute Sco

  18. Stemcell Information: SKIP000849 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Chris M. Woodard ... The New York Stem Cell Foundation Research Institute The New York Stem Cell Foundation Research Institute Scott... A. Noggle ... Scott A. Noggle ... The New York Stem Cell Foundation Research Institute The N

  19. Stemcell Information: SKIP000848 [SKIP Stemcell Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Chris M. Woodard ... The New York Stem Cell Foundation Research Institute The New York Stem Cell Foundation Research Institute Scott... A. Noggle ... Scott A. Noggle ... The New York Stem Cell Foundation Research Institute The N

  20. OPTIMAL PARTITIONS OF DATA IN HIGHER DIMENSIONS

    Data.gov (United States)

    National Aeronautics and Space Administration — OPTIMAL PARTITIONS OF DATA IN HIGHER DIMENSIONS BRADLEY W. JACKSON*, JEFFREY D. SCARGLE, AND CHRIS CUSANZA, DAVID BARNES, DENNIS KANYGIN, RUSSELL SARMIENTO, SOWMYA...

  1. Uued plaadid / Koit Raudsepp

    Index Scriptorium Estoniae

    Raudsepp, Koit

    1999-01-01

    Uutest plaatidest Chris De Burgh "Quiet Revolution", Travis "The MAn Who", Helloween "Metal Jukebox", Barbara Streisand "A Love Like Ours", Air "Premiers Symptomes", "Love Parade 1999 Music Is Tehe Key"

  2. 77 FR 12844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Development...

    Science.gov (United States)

    2012-03-02

    ... Intervention for Changing Behaviors Related to Cytomegalovirus Transmission in Pregnant Women, FOA DD12-005... Women, FOA DD12-005, initial review.'' For Further Information Contact: M. Chris Langub,...

  3. Is new technology good or bad for jobs?

    OpenAIRE

    2005-01-01

    "If men have the talent to invent new machines that put men out of work, they have the talent to put those men back to work." Chris Pissarides investigates whether President Kennedy's claim is still true.

  4. Eestlased on animatsiooni rockstaarid / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2003-01-01

    Chris Robinsoni raamat eesti animafilmidest "Between genius & utter illiteracy : a story of Estonian animation", mille andis välja kirjastus Varrak. Ka Janno Põldma ja Jaan Ruusi arvamused raamatu kohta

  5. Eesti joonisfilmi austaja esitles oma raamatut / A. R.

    Index Scriptorium Estoniae

    A. R.

    2005-01-01

    Kanadalane Chris J. Robinson esitles Viru keskuses Rahva Raamatu poes oma Varraku kirjastuse vahendusel 2003.a. ilmunud raamatut "Between Genius & Utter Illiteracy : A Story of Estonian Animation", mis on eesti animatsiooni ajalugu, mille kirjutamiseni eestlased pole veel jõudnud

  6. Pöff toob Animatsiooni Kupeldaja Eestisse

    Index Scriptorium Estoniae

    2005-01-01

    PÖFFi alafestivalist "Animated Dreams", mille raames toimub Ottawa animafilmide festivali kunstilise juhi Chris J. Robinsoni raamatu "Between Genius and Utter Illiteracy : a Story of Estonian Animation" esitlus

  7. 75 FR 70752 - Reliability Monitoring, Enforcement and Compliance Issues; Announcement of Panelists for...

    Science.gov (United States)

    2010-11-18

    ... no registration list or registration fee to attend this technical conference. For further information... Coordinating Council Douglas Curry, General Counsel, Lincoln Electric System Chris Hajovsky, Director... auditing methods also demonstrate compliance and improve reliability? Possible improvements or...

  8. Writing Programs Worldwide:

    OpenAIRE

    Restrepo Franco, María Alejandra; Pontificia Universidad Javeriana

    2013-01-01

    Chris Thaiss, Gerd Bräuer, Paula Carlino, Lisa Ganobcsik-Williams y Aparna Sinha (editores) United States of America: WAC Clearinghouse y Parlor Press, 2012, 530 p. isbn 978-1-60235-346-6 (online pub)

  9. Traditional medicine use in surgical patients in a South African ...

    African Journals Online (AJOL)

    aFaculty of Health Sciences, Chris Hani Baragwanath Academic Hospital, University of ... cDepartment of Anesthesia and Perioperative Medicine, University of Manitoba, Canada ..... Acknowledgement – K Kamndaya, School of Public Health,.

  10. The obesity pandemic, the diabetes 'tsunami', and the lack of adequate sports grounds for children in Auckland, New Zealand

    National Research Council Canada - National Science Library

    Derraik, José G B; de Bock, Martin; Ruffell, Chris; Ahlsson, Fredrik; Cutfield, Wayne S

    2011-01-01

    ...@gmail.com Dr Martin de Bock Clinical and Research Fellow, Paediatric Endocrinology, Liggins Institute, University of Auckland Auckland, New Zealand Chris Ruffell Chairman Eastern Suburbs Association Football Club (ESAFC...

  11. Näitleja Tommy Lee Jonesi meditatsioon režissööritoolis / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2007-01-01

    Vestern "Melquiades Estrada kolm matust" ("The Three Burials of Melquiades Estrada") : stsenarist Guillermo Arriaga : režissöör ja osatäitja Tommy Lee Jones : operaator Chris Menges : Ameerika Ühendriigid, 2005

  12. Animatsioon ei hammusta

    Index Scriptorium Estoniae

    2005-01-01

    IX Pimedate Ööde Filmifestivali alafestival "Animated Dreams" ja seal esinevad külalised : tšehhi animaator Michaela Pavlatova, Chris J. Robinson Kanadast, Anna Doyle Suurbritanniast. Lisatud animafestivali ajakava

  13. Euro-Atlandi telg püsib / Ilmar Mikiver

    Index Scriptorium Estoniae

    Mikiver, Ilmar, 1920-2010

    2004-01-01

    Euroopa Liidu ja NATO koostöö USA-ga terrorivastases võitluses on paremaks muutunud, sellest annab tunnistust Euroopa Komitee esimehe Romano Prodi ja Euroliidu välisasjade peavoliniku Chris Patteni ühisdeklaratsioon Euroopa kaasvastutusest

  14. Inspiring Reflections

    DEFF Research Database (Denmark)

    Muchie, Mammo

    2011-01-01

    contributions have been put together. There are a number of ways to continue Chris Freeman's legacy on innovation research. The first is to build in a critical tradition in the economics of innovation research by introducing fearlessly emancipatory epistemology. Second the economic system that dominates social......A numberof Chris Freeman's colleagues were asked to reflect on what they thought describes his life and work in a few words. Some of the colleagues replied including former SPRU students that were taught or supervised by Chris Freeman. Their views on what they thought were Chris Freeman's defining...... life is not free from fluctuations, cycles, disruptions, crises and destructions both human and ecological. Innovation research ought to position itself to address environmental, financial and economic crises. The third is innovation research for development by addressing not only poverty erdaication...

  15. Pöff toob Animatsiooni Kupeldaja Eestisse

    Index Scriptorium Estoniae

    2005-01-01

    PÖFFi alafestivalist "Animated Dreams", mille raames toimub Ottawa animafilmide festivali kunstilise juhi Chris J. Robinsoni raamatu "Between Genius and Utter Illiteracy : a Story of Estonian Animation" esitlus

  16. Eesti joonisfilmi austaja esitles oma raamatut / A. R.

    Index Scriptorium Estoniae

    A. R.

    2005-01-01

    Kanadalane Chris J. Robinson esitles Viru keskuses Rahva Raamatu poes oma Varraku kirjastuse vahendusel 2003.a. ilmunud raamatut "Between Genius & Utter Illiteracy : A Story of Estonian Animation", mis on eesti animatsiooni ajalugu, mille kirjutamiseni eestlased pole veel jõudnud

  17. Eestlased on animatsiooni rockstaarid / Tiit Tuumalu

    Index Scriptorium Estoniae

    Tuumalu, Tiit, 1971-

    2003-01-01

    Chris Robinsoni raamat eesti animafilmidest "Between genius & utter illiteracy : a story of Estonian animation", mille andis välja kirjastus Varrak. Ka Janno Põldma ja Jaan Ruusi arvamused raamatu kohta

  18. Popeye in de Kaukasus : zoektocht naar wilde spinazie (interview met C. Kik)

    NARCIS (Netherlands)

    Nijland, R.; Kik, C.

    2011-01-01

    Chris Kik van de Wageningse genenbank reisde door de zuidelijke Kaukasus om het zaad van wilde spinazie te verzamelen. Veredelingsbedrijven wachtten gretig op zijn terugkeer; zij zitten te springen om vers bloed voor de spinazieteelt.

  19. Popmuusika / Margus Haav

    Index Scriptorium Estoniae

    Haav, Margus, 1969-

    2006-01-01

    Uutest heliplaatidest Def Räädu "Succiety", Sepeltura "The BEst Of", "Reich Remixed", Chris Rea "The Road To Hell & Back", Solveig Slettahjell "Good Rain", The Fratellis "Costello Music", Siouxsie And The Banshees "VoicesOn The Air"

  20. Quick lessons on environmental nanotech

    Science.gov (United States)

    Toumey, Chris

    2015-07-01

    The use of silver nanoparticles to clean clothes and the use of magnetite nanoparticles to clean water provide contrasting illustrations of the potential environmental consequences of nanotechnology, as Chris Toumey explains.

  1. THE DEADLY DOZEN OF CHEST TRAUMA

    African Journals Online (AJOL)

    Enrique

    Severe chest injuries are responsible for 25% of all trauma deaths, and in a ... mechanical compression of the trachea, laryngeal trauma such as thyroid or cricoid ... Unit Head at Chris Hani .... mechanical ventilation to 'internally splint' the ...

  2. Tagaotsitav "Auto" / Kristiina Vaarik

    Index Scriptorium Estoniae

    Vaarik, Kristiina

    2001-01-01

    Chris O'Connelli "Auto" Vanemuises, lavastaja Mark Babych. Etendusele tegid muusika ansamblist Bizarre tuntud muusikud Tristan Priimägi ja Lauri Liivak, kes artiklis sellest räägivad. Esietendus 2. detsembril 2000

  3. Väike tõlkeraamatu-rehnut / Kalev Kesküla, Ilvi Liive

    Index Scriptorium Estoniae

    Kesküla, Kalev, 1959-2010

    2005-01-01

    18.-22. mail toimus Käsmu loomemajas eesti kirjanduse muudesse keeltesse tõlkijate seminar. Sisaldab nimekirja "Eesti kirjandus inglise keeles" [2003-2006]. Tõlkijad Eric Dickens, Fiona Sampson, Chris Moseley, Christopher Maclehose, Vera Ruber, Vishnu Khare

  4. TBT recommends : Courtney Pine. Hansa disco night

    Index Scriptorium Estoniae

    2005-01-01

    Inglise jazzsaksofonisti Courtney Pine heliplaadi "Resistance" esitluskontserdist 15. dets. Rock Cafés Tallinnas. Inglise laulja Chris Norman läti ansamblitega üritusel "Hansa disco night Nr.4" 9. dets. Kipsala Hallis Riias

  5. Puitpilvelõhkuja on valmis!

    Index Scriptorium Estoniae

    2008-01-01

    Üheksakorruseline ristkihtpuitpaneelidest korterelamu Londonis. Arhitektid: Sophie Goldhill, Chris Gray, Kristen Haggart, Andrew Waugh arhitektuuribüroost Waugh Thistleton. Konstruktorid: Megan Yates, Matthew Linegar, Bruno Dujič. Ristlamineeritud puitpaneelid valmistas Austria firma KLH

  6. Harry, kes vallutab maailma / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2001-01-01

    Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseeringu esilinastus Eestis on 21. detsembril Coca-Cola Plazas. Selle USA filmi režissöör on Chris Columbus ja peaosas 12-aastane Daniel Radcliffe

  7. A COMPARATIVE STUDY OF ALGORITHMS FOR LAND COVER CHANGE

    Data.gov (United States)

    National Aeronautics and Space Administration — A COMPARATIVE STUDY OF ALGORITHMS FOR LAND COVER CHANGE SHYAM BORIAH*, VARUN MITHAL, ASHISH GARG, VIPIN KUMAR, MICHAEL STEINBACH, CHRIS POTTER, AND STEVE KLOOSTER*...

  8. A Bioassay Experiment to Determine Water Quality Impacts Related to Trout Mortality at a Hatchery Downstream of Lake Sidney Lanier, Georgia.

    Science.gov (United States)

    1982-03-01

    Erikson, Chemistry Jim Rosenbauer, Biology Project Technicians Ray Lewis, Aquaculture Chris Newman, Biological Technician Lisa Grant, Biological Technician...temperature destratifying turbulence is created. Air is less expensive than oxygen, but hypolimnetic aeration produces nitrogen supersaturation which can be

  9. Unistus saab reaalsuseks / Kadri Kaldam

    Index Scriptorium Estoniae

    Kaldam, Kadri

    2008-01-01

    Arhitektuuri ja disaini veebiportaali Architonic salong Kölni mööblimessil. Projekteerija: LAVA (Laboratory for Visionary Architecture, Stuttgart, Sydney). Arhitektid: Tobias Wallisser, Chris Bosse. Loov meeskond: Kadri Kaldam, Stephan M. Albrecht, Kristof Gavrielides

  10. Ameerika närvilised geeniused / Karlo Funk

    Index Scriptorium Estoniae

    Funk, Karlo, 1971-

    2000-01-01

    IV Pimedate Ööde Filmifestivali filmidest : "Olles John Malkovich" ("Being John Malkovich") : režissöör Spike Jonze ja dokumentaalfilm "Ameerika film" ("American Movie") : režissöör Chris Smith

  11. Animatsioon ei hammusta

    Index Scriptorium Estoniae

    2005-01-01

    IX Pimedate Ööde Filmifestivali alafestival "Animated Dreams" ja seal esinevad külalised : tšehhi animaator Michaela Pavlatova, Chris J. Robinson Kanadast, Anna Doyle Suurbritanniast. Lisatud animafestivali ajakava

  12. NIGERIA AND DEVELOPMENT IN THE 21ST CENTURY ...

    African Journals Online (AJOL)

    Precious

    feelings, aspirations and the sensibilities to arouse and galvanize the public who unfortunately .... It is stimulation of communities to change their own affairs ... as hospitals, electricity, pipe-borne water, airports and express roads. Again, Chris ...

  13. Pjat smertnõhh grehhov Garri Pottera (s posledujushtshim razoblatshenijem) / Nikolai Karajev

    Index Scriptorium Estoniae

    Karajev, Nikolai, 1978-

    2003-01-01

    Vastukajasid J.K. Rowling'u Harry Potteri lugudele, kuna ekraanile jõuab teine nende ekraniseering "Harry Potter ja saladuste kamber" ("Harry Potter and the Chamber of Secrets") : režissöör Chris Columbus

  14. Heroin Epidemic Expands Its Grip on America

    Science.gov (United States)

    ... The issue is so pressing that President Donald Trump plans to announce the formation of a commission ... Gov. Chris Christie will chair the commission. The Trump administration also named Richard Baum to serve as ...

  15. Näitleja Tommy Lee Jonesi meditatsioon režissööritoolis / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2007-01-01

    Vestern "Melquiades Estrada kolm matust" ("The Three Burials of Melquiades Estrada") : stsenarist Guillermo Arriaga : režissöör ja osatäitja Tommy Lee Jones : operaator Chris Menges : Ameerika Ühendriigid, 2005

  16. A two round debate

    Directory of Open Access Journals (Sweden)

    Donatella Persico

    1993-01-01

    Full Text Available Intervento “a piu’ voci” sulla definizione del concetto delle Tecnologie Didattiche. Contribuiscono Chris Bell (Inghilterra, Vittorio Midoro (Italia, Alistair Thomson (Scozia, Lydia Tornatore (Italia.

  17. [Breeding bird survey authorization : Audubon National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This letter authorizes Larry Igl and Chris Johnson to conduct population estimates of breeding birds on Audubon National Wildlife Refuge. This study is in...

  18. Puitpilvelõhkuja!

    Index Scriptorium Estoniae

    2007-01-01

    Londonisse ehitatava 9-korruselise korterelamu projektist. Hoone ehitatakse ristlamineeritud puitpaneelidest (jumbo plywood), fassaadidel olevad pikseldatud mustrid on inspireeritud Gerhard Richteri maalikunstist. Arhitektid: Sophie Goldhill, Chris Gray, Kristen Haggart, Andrew Waugh. Projekteerija: Waugh Thistleton

  19. Plenty of gloom and doom at the bottom?

    Science.gov (United States)

    Toumey, Chris

    2009-07-01

    The relationship between humans and technology is often viewed as a debate between technophobes who oppose technology, irrespective of its benefits, and technophiles who think that all technology is good. Chris Toumey prefers the cyborg point of view.

  20. fireforce - one man's war in the rhodesian light infantry

    African Journals Online (AJOL)

    The history of the Rhodesian Light Infantry is an illustrious one. The. RLI produced many of the senior brass who led the Rhodesian Army including Gen ... contains three sections of colour photographs, mainly taken from Chris. Cocks' private ...

  1. Nanobots today

    Science.gov (United States)

    Toumey, Chris

    2013-07-01

    Nanobots have in the past been a fixture of science fiction writing and illustration, and such ideas are now also appearing in scientific research. But, as Chris Toumey explains, practical nanobots are different from their science fiction counterparts.

  2. Argipäev pärast karjääri / Madli Zobel, Tiina Laanem

    Index Scriptorium Estoniae

    Zobel, Madli, 1976-

    2005-01-01

    Ettevõtluses ja poliitikas juhtivatel positsioonidel olnud Monika Salu läbipõlemisest ning tööst tagasitõmbumisest. Kommenteerivad siseministri abi Zanna Tamberg ja Fontese konsultant Chris-Helin Loik

  3. Willow Flycatcher Habitat Model Results [ds278

    Data.gov (United States)

    California Department of Resources — This dataset was developed by Chris Stermer (CDFG - RAP Program). No original metadata were located, but the following is an abstract from a document describing the...

  4. Climate Governance is Failing Us: We All Need to Respond

    Directory of Open Access Journals (Sweden)

    Chris Riedy

    2011-12-01

    Full Text Available Peer reviewed introduction to the Special Issue on Global Climate Change Policy: Post-Copenhagen Discord, guest edited by Chris Riedy and Ian M. McGregor, University of Technology, Sydney.

  5. Plaadid / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2002-01-01

    Uutest plaatidest David Guetta "Just A Little More Love", Bond "Shine", Chris de Burgh "Timing Is Everything...", Diana Krall "Live In Paris", Richard Ascroft "Human Conditions", Rein Laaneorg "Teine elu", Leaves "Breathe", Derek Trucks Band "Jouful Noise"

  6. TBT recommends : Courtney Pine. Hansa disco night

    Index Scriptorium Estoniae

    2005-01-01

    Inglise jazzsaksofonisti Courtney Pine heliplaadi "Resistance" esitluskontserdist 15. dets. Rock Cafés Tallinnas. Inglise laulja Chris Norman läti ansamblitega üritusel "Hansa disco night Nr.4" 9. dets. Kipsala Hallis Riias

  7. Viis talvist kinomüsteeriumi / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2009-01-01

    Aastalõpus Eestis linastuvatest põnevusfilmidest tutvustavalt: Euroopa filmide valik Tallinnfilmi kinodes, James Cameroni "Avatar", Chris Weitz'i "Videviku saaga: Noorkuu", Terry Gilliami "Doktor Parnassuse Imaginaarium" ja Guy Ritchie "Sherlock Holmes"

  8. Harry Potter jõudis ekraanile / Ilona Martson

    Index Scriptorium Estoniae

    Martson, Ilona, 1970-

    2001-01-01

    Eile oli Londonis Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseeringu esilinastus. Selle 125 miljonit dollarit maksnud USA filmi režissöör on Chris Columbus ja peaosas 12-aastane Daniel Radcliff

  9. Mis saab maast, kui päike kustub? / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2007-01-01

    Ulmefilm "Päikesepaiste" ("Sunshine") : režissöör Danny Boyle : Suurbritannia 2007. Lisaks Oxfordi ülikooli teadlase, dr. Chris Lintotti kommentaar "Tunnustatud teadlane : "Jabur idee, aga realistlik teostus"

  10. Harry Potter jõudis ekraanile / Ilona Martson

    Index Scriptorium Estoniae

    Martson, Ilona, 1970-

    2001-01-01

    Eile oli Londonis Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseeringu esilinastus. Selle 125 miljonit dollarit maksnud USA filmi režissöör on Chris Columbus ja peaosas 12-aastane Daniel Radcliff

  11. Ameerika närvilised geeniused / Karlo Funk

    Index Scriptorium Estoniae

    Funk, Karlo, 1971-

    2000-01-01

    IV Pimedate Ööde Filmifestivali filmidest : "Olles John Malkovich" ("Being John Malkovich") : režissöör Spike Jonze ja dokumentaalfilm "Ameerika film" ("American Movie") : režissöör Chris Smith

  12. Lessons from before and after nanotech

    Science.gov (United States)

    Toumey, Chris

    2012-10-01

    Ethical questions arising from biotechnology first, then nanotechnology, and synthetic biology now, present common features, but as Chris Toumey explains, the scientific and ethical issues arising in each case should be treated individually.

  13. 76 FR 6604 - Certain Pasta From Italy: Extension of Time Limit for the Preliminary Results of the...

    Science.gov (United States)

    2011-02-07

    ...: Scott Holland or Chris Siepmann, AD/ CVD Operations, Office 1, Import Administration, U.S. Department of... Secretary for Antidumping and Countervailing Duty Operations. BILLING CODE 3510-DS-P ...

  14. Uued plaadid / Koit Raudsepp

    Index Scriptorium Estoniae

    Raudsepp, Koit

    1999-01-01

    Uutest plaatidest Chris De Burgh "Quiet Revolution", Travis "The MAn Who", Helloween "Metal Jukebox", Barbara Streisand "A Love Like Ours", Air "Premiers Symptomes", "Love Parade 1999 Music Is Tehe Key"

  15. Viis talvist kinomüsteeriumi / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2009-01-01

    Aastalõpus Eestis linastuvatest põnevusfilmidest tutvustavalt: Euroopa filmide valik Tallinnfilmi kinodes, James Cameroni "Avatar", Chris Weitz'i "Videviku saaga: Noorkuu", Terry Gilliami "Doktor Parnassuse Imaginaarium" ja Guy Ritchie "Sherlock Holmes"

  16. A Smarter Intelink: Intelligence Information Management to Support the Operational Commander

    Science.gov (United States)

    2005-02-14

    visible” to webcrawlers; this same phenomenon plagues the internet as well, and such data is said to reside in the “ Invisible Web ,” which has been...2005. 12 Sherman, Chris. “Search for the Invisible Web ,” The Guardian Unlimited Online, 06 September 2001, <http://www.guardian.co.uk/online/story...0,3605,547140,00.html>. [01 February 2005] 13Johns, E-mail. 14 Chris Sherman and Gary Price, The Invisible Web . (Medford, NJ:Information Today

  17. Fuel Reduction for the Mobility Air Forces

    Science.gov (United States)

    2015-01-01

    20 Michael Kennedy, Laura H. Baldwin , Michael Boito, Katherine M. Calef, James Chow, Joan Cornuet, Mel Eisman, Chris Fitzmartin, J.R. Gebman, Elham...Michael, Laura H. Baldwin , Michael Boito, Katherine M. Calef, James Chow, Joan Cornuet, Mel Eisman, Chris Fitzmartin, J. R. Gebman, Elham Ghashghai...C O R P O R A T I O N Research Report Fuel Reduction for the Mobility Air Forces Christopher A. Mouton, James D. Powers, Daniel M. Romano

  18. Interaktiivse filmi näitus ja seminar Tartus

    Index Scriptorium Estoniae

    2004-01-01

    12. II viidi TÜ raamatukogus läbi Chris Halesi (Inglismaa) ja Teijo Pellineni (Soome) juhtimisel show "Cause and Effect". 13. II Tartu Kunstimajas seminar "Interaktiivne narratiiv ja digitaalne film", kus esinevad Chris Hales, Morten Schjudt (Taani) ja Klaas Kuitenbrouwer (Holland). Korraldaja: Tartu Kõrgema Kunstikooli meedia- ja reklaamikunsti osakond. Avatakse kõrgema kunstikooli üliõpilaste interaktiivse filmi projektide näitus "In-Cinema"

  19. Retention of Digital Skills: Command Post of the Future

    Science.gov (United States)

    2011-01-01

    Chris Curl, Paul Welsch, Shirley DeGroot, Timothy Livesy, Ed Smith, Dave Wardlow, and Barry Wilson. Chris Strauss, David James, and Paul ...Catrambone, 1998; Ericsson, Krampe, & Tesch- Romer , 1993). As a result, there will likely be more forgetting for the higher-level CPOF skills than for...Performance, 12, 31-57. Ericsson, K. A., Krampe, R. T., & Tesch- Romer , C. (1993). The role of deliberate practice in the acquisition of expert

  20. Biodynamic Assessment of Pilot Knee-Board Configurations During Simulated T-38 Catapult Acceleration

    Science.gov (United States)

    2015-04-01

    0041 Biodynamic Assessment of Pilot Knee -Board Configurations During Simulated T-38 Catapult Acceleration Mr. Chris Perry Mr. Chris...to April 2015 4. TITLE AND SUBTITLE Biodynamic Assessment of Pilot Knee -Board Configurations During Simulated T-38 Catapult Acceleration 5a...and converted to AVI format, and stored in the RH Collaborative Biomechanics Data Bank. Photographs were taken of the test set-up prior to each test

  1. Interaktiivse filmi näitus ja seminar Tartus

    Index Scriptorium Estoniae

    2004-01-01

    12. II viidi TÜ raamatukogus läbi Chris Halesi (Inglismaa) ja Teijo Pellineni (Soome) juhtimisel show "Cause and Effect". 13. II Tartu Kunstimajas seminar "Interaktiivne narratiiv ja digitaalne film", kus esinevad Chris Hales, Morten Schjudt (Taani) ja Klaas Kuitenbrouwer (Holland). Korraldaja: Tartu Kõrgema Kunstikooli meedia- ja reklaamikunsti osakond. Avatakse kõrgema kunstikooli üliõpilaste interaktiivse filmi projektide näitus "In-Cinema"

  2. Incorporation Kinetics in Mixed Anion Compound Semiconductor Alloys

    Science.gov (United States)

    2013-01-01

    PROGRAM ELEMENT NUMBER 611102 6. AUTHORS Sd. PROJECT NUMBER Joanna M. Milhmchick, Evan M . Anderson, Chris Pearson, Wendy L. Samey, Stefan P. Svensson...Chris Pearson, Department of Computer Science, Engineering, and Physics, University of Michigan–Flint, Flint, MI 48502 Wendy L. Sarney and Stefan P...M.H. Francombe, and C.E.C. Wood , J Appl Phys 52, 7416 (1981). 27 B.W. Liang and C.W. Tu, J Cryst Growth 128, 538 (1993). 14 12 Table 1

  3. Semi Automated Ferrous Material Scouring System (SAFMSS)

    Science.gov (United States)

    2016-03-14

    FINAL REPORT Semi-Automated Ferrous Material Scouring System (SAFMSS) ESTCP Project MR-201102 MARCH 2016 Dr. Herman Herman Mr. Chris Fromme...Include area code) 03/14/2016 Final Report July 2011 - March 2016 Semi-Automated Ferrous Material Scouring System (SAFMSS) Chris Fromme Herman Herman... Ferrous Material Scouring System (SAFMSS) March 14, 2016 ii Approved for public release; distribution is unlimited TABLE OF CONTENTS TABLE OF

  4. Alcoholism and memory: broadening the scope of alcohol-expectancy research.

    Science.gov (United States)

    Goldman, M S; Brown, S A; Christiansen, B A; Smith, G T

    1991-07-01

    Current biopsychosocial research on the etiology of alcoholism has begun to focus on memory processes as a possible common pathway for drinking decisions. The alcohol-expectancy construct is rooted both in cognitive psychology and alcohol research and can serve as a vehicle for this study. Reexamination of one recent review of issues in alcohol-expectancy research provides an opportunity to broaden the scope of this research with theoretical and methodological alternatives to those suggested in that review. Most importantly, this article shows that expectancy findings, discussed by Leigh (1989a) as reflecting "psychometric" limitations, are instead quite consistent with recent network models of memory structure. Such models can provide an informative guide to future research activities. It is also recommended that alcohol-expectancy research remain open to inputs from expectancy theories already developed in several psychological domains, as well as to theories of social cognition and attitude structure in addition to those advanced by Leigh.

  5. Efficient Decoding of Turbo Codes with Nonbinary Belief Propagation

    Directory of Open Access Journals (Sweden)

    Thierry Lestable

    2008-05-01

    Full Text Available This paper presents a new approach to decode turbo codes using a nonbinary belief propagation decoder. The proposed approach can be decomposed into two main steps. First, a nonbinary Tanner graph representation of the turbo code is derived by clustering the binary parity-check matrix of the turbo code. Then, a group belief propagation decoder runs several iterations on the obtained nonbinary Tanner graph. We show in particular that it is necessary to add a preprocessing step on the parity-check matrix of the turbo code in order to ensure good topological properties of the Tanner graph and then good iterative decoding performance. Finally, by capitalizing on the diversity which comes from the existence of distinct efficient preprocessings, we propose a new decoding strategy, called decoder diversity, that intends to take benefits from the diversity through collaborative decoding schemes.

  6. Sex differences in time to task failure during early pubertal development.

    Science.gov (United States)

    Rudroff, Thorsten; Holmes, Matthew R; Melanson, Edward L; Kelsey, Megan M

    2014-06-01

    We compared fatigability and activation of elbow flexor muscles in children at 3 pubertal stages during a sustained submaximal contraction. In 72 healthy children (39 boys) aged 11 ± 3 years (range, 8-14 years), differences in fatigability (time to task failure) and muscle activation were compared at 3 Tanner stages (T1-T3). Time to task failure and muscle activation were similar between boys and girls at prepubertal Tanner stage 1. Time to task failure was briefer for girls than boys at Tanner stages 2 and 3 and was predicted by the coactivation indices and percent body fat in girls. Muscle torque was the only predictor for the time to task failure in boys. Differences in fatigability and muscle coactivation were evident during the initial pubertal stages (T2 and T3), but not before the onset of puberty (T1). Copyright © 2013 Wiley Periodicals, Inc.

  7. RF Plasma Annealing on MOS Structures.

    Science.gov (United States)

    1981-12-01

    with =012 -1I LE = 0.03 eV and va - 1 sec , the calculated EM is 1.1 eV. As reported by many previous workers ( Fanet and Poirier 1974, DiMaria 1978...Butler, "Charge Trapping and Associated Luminescence in MOS Oxide Layers." Leigh University (1980). J. M. Fanet and R. Poirier, "Charge Storage in 5i02

  8. NATO Planning Guide for the Estimation of Chemical, Biological, Radiological, and Nuclear (CBRN) Casualties (AMedP-8(C)) - Parameters for Estimation of Casualties from Exposure to Specified Biological Agents. Addenda to Allied Medical Publication 8

    Science.gov (United States)

    2011-01-01

    headache, chest pain, myalgia, elevated temperature, vomiting , nausea, and anorexia. Non-productive cough. S/S Severity 3 (Severe) 1 (Mild...Symptoms (S/S) Cough, headache, chest pain, myalgia, elevated temperature, vomiting , nausea, and anorexia. S/S Severity 3 (Severe) Outlook...Anno, George H., Michael Lockhart, Larry Karns, Gene E. McClellan, Gillian L. Rickmeier, Ronald M. Bloom, and Leigh N. Matheson. Biological

  9. Veneetsia festivali võitis Briti film aborditegijast / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2004-01-01

    Veneetsia 61. filmifestivali võitjad : Kuldlõvi sai inglase Mike Leigh "Vera Drake" (nimiosa eest ka parima naisnäitleja Coppa Volpi Imelda Stauntonile), Hõbelõvi läks hispaanlase Alejandro Amenabari filmile "Sisemeri" (siit ka parima meesnäitleja au Javier Bardemile), režii eriauhinna sai Kim Ki-duk Lõuna-Koreast filmiga "Tühi maja"

  10. Objavlenõ pobediteli Venetsianskogo kinofestivalja

    Index Scriptorium Estoniae

    2004-01-01

    Veneetsia 61. filmifestivali võitjad : Kuldlõvi sai inglase Mike Leigh "Vera Drake" (nimiosa eest ka parima naisnäitleja Coppa Volpi Imelda Stauntonile), Hõbelõvi läks hispaanlase Alejandro Amenabari filmile "Merele" (siit ka parima meesnäitleja au Javier Bardemile), režii eriauhinna sai Kim Ki-duk Lõuna-Koreast filmiga "Tühi maja" ("Binjip")

  11. Artificial and Natural Icing Tests of AH-64. Phase 2

    Science.gov (United States)

    1987-03-01

    Cambridge model 137 chilled mirror dew point hygrometer and display, Leigh Mk 12 ice detector unit. Cloud Technology Inc., model LWH-1 (Johnson...probes (gm/m^) 10. The Cloud Technology Ice detector has a calibrated resistance wire which Is mounted In the alrstream and connected as one branch...Cambridge model 137 chilled mirror dew point hygrometer and display, Cloud Technology ice detector unit, and a Small Intelligent Icing Data System (SUDS

  12. Guide to Canadian Aerospace Related Industries,

    Science.gov (United States)

    1984-03-01

    Remote Sensing 5. 7, 9, 17, 18 STI SAR 1, 15, 18 MDA Remote Sensing 9 ULI Satellite Communications 5. 18 MCS Removable Media Mass Satellite Communications...rnltary maKets ments of National Defense and Transport Leigh was founded in 1961 and is a pubhicly held Canadia-’ owned company Approximately 50K. of sales...and value of data is of paramount importance. social services management systems, health care, videotex Their equipment is ideally suited to handle

  13. Disease: H00644 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available lity syndrome is a very rare genodermatosis that develops skin fragility with tearing and blisters and conge.... Developmental disorder; Skin and connective tissue disease PKP1 [HSA:5317] [KO:K10387] MeSH: C536183 OMIM:...n 28:125-9 (2010) PMID:9326952 (gene) McGrath JA, McMillan JR, Shemanko CS, Runswick SK, Leigh IM, Lane EB, Garrod DR, Ea

  14. Status Report on Speech Research: A Report on the Status and Progress of Studies on the Nature of Speech, Instrumentation for its Investigation, and Practical Application.

    Science.gov (United States)

    1986-03-01

    Chagnon Donald Hailey Nancy O’Brien Alice Dadourian Raymond C. Huey* William P. Scully Michael D’Angelo Sabina D. Koroluk Richard S. Sharkany Betty J...Franklin S. Cooper* Isabelle Y. Liberman* Donald Shankweiler* Stephen Crain* Leigh Lisker* Michael Studdert-Kennedy* Robert Crowder* Virginia Mann* Betty ...secondary cue . -. .. value. The "ideal" contours found in earlier work (Abramson, 1962; Erickson , %. 1974; Gandour, 1975) are still quite acceptable

  15. Reactive oxygen species act remotely to cause synapse loss in a Drosophila model of developmental mitochondrial encephalopathy

    OpenAIRE

    2008-01-01

    Mitochondrial dysfunction is a hallmark of many neurodegenerative diseases, yet its precise role in disease pathology remains unclear. To examine this link directly, we subtly perturbed electron transport chain function in the Drosophila retina, creating a model of Leigh Syndrome, an early-onset neurodegenerative disorder. Using mutations that affect mitochondrial complex II, we demonstrate that mild disruptions of mitochondrial function have no effect on the initial stages of photoreceptor d...

  16. Perfektse käsitöö poeetiline realism / Aare Ermel

    Index Scriptorium Estoniae

    Ermel, Aare, 1957-2013

    1999-01-01

    Rootsi filmiklassik Jan Troell (1931) ja tema filmid ning mängufilmid "Läbisegi" ("Topsy-Turvy") : režissöör Mike Leigh, "Rotipüüdja" ("Ratcatcher") : režissöör Lynne Ramsay ja "Püssirohutünn" ("Pure baruta") : režissöör Goran Paskaljevic Tallinnas III Pimedate Ööde Filmifestivalil

  17. SiLK: A Tool Suite for Unsampled Network Flow Analysis at Scale

    Science.gov (United States)

    2014-06-01

    SiLK : A Tool Suite for Unsampled Network Flow Analysis at Scale Mark Thomas, Leigh Metcalf, Jonathan Spring, Paul Krystosek, Katherine Prevost netsa...make the problem manageable, but sampling unacceptably reduces the fidelity of ana- lytic conclusions. In this paper we discuss SiLK , a tool suite...created to analyze this high-volume data source without sampling. SiLK implementation and archi- tectural design are optimized to manage this Big Data

  18. Catalysts for Lightweight Solar Fuels Generation

    Science.gov (United States)

    2017-03-10

    Conference on Proton-Coupled Electron Transfer; Skokloster Wärdshus, Sweden ; 18 June 2014. 73. ICPP-8; Istanbul, Turkey; 26 June 2014. 74. Materials... Sweden ; 28 April 2015. 107. Public Lecture; Uppsala, Sweden ; 29 April 2015. 108. Anthony J. and Heand Johns Silvestri Lectureship in Chemistry...Academy Lecture, Royal Swedish Academy of Sciences; Stockholm, Sweden ; 8 March 2017. 8. Honors 8.1 Awards 1. Leigh Ann Conn Prize in Renewable Energy

  19. Efficacy of the low FODMAP diet for treating irritable bowel syndrome: the evidence to date

    OpenAIRE

    Nanayakkara WS; Skidmore PML; O’Brien L; Wilkinson TJ; Gearry RB

    2016-01-01

    Wathsala S Nanayakkara,1 Paula ML Skidmore,1 Leigh O'Brien,2 Tim J Wilkinson,3 Richard B Gearry,31Department of Human Nutrition, University of Otago, Dunedin, New Zealand; 2Dietary Specialists, Christchurch, New Zealand; 3Department of Medicine, University of Otago, Christchurch, New Zealand Abstract: This review summarizes the published clinical studies concerning the management of irritable bowel syndrome (IBS) using restriction of Fermentable Oligosaccharide, Disaccharide, Monosac...

  20. Assessing Performance Outcomes of New Graduates Utilizing Simulation in a Military Transition Program

    Science.gov (United States)

    2013-01-01

    reproduction of this article is prohibited. Jeffries, P. R. (2007). Simulation in nursing education . New York, NY: National League for Nursing. Kardong...Application of Benner’s theory in an interactive patient care simulation. Nursing Education Perspectives, 27(1), 16Y22. Leigh, G. (2011). The simulation...Applying theoretical frameworks to simulation in nursing education . International Journal of Nursing Education Scholarship, 4(1), 1Y14. 148

  1. Estrogen Receptor Mutants/Variants in Human Breast Cancer.

    Science.gov (United States)

    1996-12-01

    Bethesda, MD, USA). detection sensitivity and increases the Human immunodeficiency virus type 2 Tamara Hiller, Linda Snell yield of the amplified products...was McBride- Putman 2 , S. Fuqua2, R. Luput. ’Georgetown University, Washington, D.C. observed for the estrogen receptor, cyclin DI, and CerbB-2. (3) A...Leygue, Linda Snell, Leigh C. Murphy and Peter H. Watson * *Affiliations of authors: A. Huang, L. Snell, and P.H. Watson (Department of Pathology), E

  2. Veneetsia festivali võitis Briti film aborditegijast / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2004-01-01

    Veneetsia 61. filmifestivali võitjad : Kuldlõvi sai inglase Mike Leigh "Vera Drake" (nimiosa eest ka parima naisnäitleja Coppa Volpi Imelda Stauntonile), Hõbelõvi läks hispaanlase Alejandro Amenabari filmile "Sisemeri" (siit ka parima meesnäitleja au Javier Bardemile), režii eriauhinna sai Kim Ki-duk Lõuna-Koreast filmiga "Tühi maja"

  3. Adult-onset Leigh′s disease: A rare entity

    Directory of Open Access Journals (Sweden)

    Shaik Afshan Jabeen

    2016-01-01

    Full Text Available Leigh syndrome (LS is a heterogeneous familial or sporadic neurodegenerative disorder. It is typically seen in infancy or childhood, although rare cases of adult onset have been described. The authors describe a 37-year-old woman who presented with protracted gastrointestinal symptoms followed by acute brain stem syndrome with severe metabolic acidosis and who subsequently showed dramatic clinical and neuroradiological improvement.

  4. Objavlenõ pobediteli Venetsianskogo kinofestivalja

    Index Scriptorium Estoniae

    2004-01-01

    Veneetsia 61. filmifestivali võitjad : Kuldlõvi sai inglase Mike Leigh "Vera Drake" (nimiosa eest ka parima naisnäitleja Coppa Volpi Imelda Stauntonile), Hõbelõvi läks hispaanlase Alejandro Amenabari filmile "Merele" (siit ka parima meesnäitleja au Javier Bardemile), režii eriauhinna sai Kim Ki-duk Lõuna-Koreast filmiga "Tühi maja" ("Binjip")

  5. Role of contact line evaporation on the spreading of viscous droplet

    Science.gov (United States)

    Bou-Zeid, Wassim; Brutin, David

    2014-11-01

    The effect of relative humidity and viscosity on the spreading dynamics of water-glycerol mixtures was analyzed for a range of relative humidities from 20% to 80%. Droplets of identical volume were deposited on ultra-clean microscope glass substrates. We demonstrated that, in addition to the competition between viscous forces, capillary forces and disjoining pressure, droplet spreading was also affected by the evaporation that occurred at the triple line. We provide an updated Tanner's law, which was modified to take into account the evaporative contribution. The same mechanism can be applied to adjust any fluid to Tanner's coefficient of 1/10.

  6. The need for revised standards for skinfold thickness in infancy

    OpenAIRE

    Paul, A; Cole, T; Ahmed, E.; WHITEHEAD, R.

    1998-01-01

    Skinfold standards provide a useful indication of subcutaneous fat. To evaluate skinfold thickness of 252 Cambridge infants over the first 2 years of age, SD scores relative to the Tanner standards were calculated, taking account of skewness in the standards. Cambridge SD scores were low, varying according to age from −1.2 to −1.8 for triceps and −0.6 to −1.2 for subscapular skinfolds. The Tanner skinfold standards were last revised 30 years ago, at a time of high prevale...

  7. Historical environmental pollution trend and ecological risk assessment of trace metals in marine sediments off Adyar estuary, Bay of Bengal, India.

    Digital Repository Service at National Institute of Oceanography (India)

    Veerasingam, S.; Venkatachalapathy, R.; Ramkumar, T.

    electroplating industries around the study area (Tanner and Leong 2000). The enhancement of Cr concentrations in the surface layers indicates that it is present as Cr(VI), which is relatively mobile and after release to the pore waters, it migrates downward... Microprobe Tech 17:209–217 Soylak M, Divrikli U, Saracoglu S, Elci L (2002) Monitoring trace metal levels in Yozgat-Turkey: copper, iron, nickel, cobalt, lead, cadmium, manganese and chromium levels stream sediments. Pol J Environ Stud 11:47–51 Tanner PA...

  8. Dynamic Decision Making in Complex Task Environments: Principles and Neural Mechanisms

    Science.gov (United States)

    2013-03-01

    theory (Tanner, & Swets, 1954) and the random walk model, providing the basis of the sequential probability ratio test ( Wald and Wolfowitz , 1948...perceptual choice: The leaky, competing accumulator model. Psychological Review, 108, 550–592. Wald , A. & Wolfowitz , J. (1948). Optimum Character of the

  9. Health Care. The State of the Industry. Spring 2008

    Science.gov (United States)

    2008-01-01

    07useconomics_emanuel.aspx ( accesed May 19, 2008). 89. Michael F. Cannon and Michael D. Tanner, Healthy Competition - What’s Holding Back Health Care and how to Free It...Comprehensive Cure: Universal Health Care Vouchers. The Bookings Institute. http://www.brookings.edu/papers/2007/ 07useconomics_emanuel.aspx ( accesed May 19

  10. The Effect of School Design on Student Performance

    Science.gov (United States)

    Ariani, Mohsen Ghasemi; Mirdad, Fatemeh

    2016-01-01

    The present study aims at exploring the influence of school design on student performance. The participants consisted of 150 students who studied at two Iranian public school and private school in Mashhad City. School Design and Planning Laboratory (SDPL) model of Georgia University (and Tanner (2009)) was used as an appraisal indicator of school…

  11. Mark Twain: A Collection of Critical Essays. Twentieth Century Views Series.

    Science.gov (United States)

    Smith, Henry Nash, Ed.

    One of a series of works aimed at presenting contemporary critical opinion on major authors, this collection includes essays by Henry Nash Smith, Van Wyck Brooks, Maurice Le Breton, Kenneth Lynn, Leo Marx, Walter Blair, Daniel G. Hoffman, W. H. Auden, James M. Cox, Leslie Fiedler, Bernard DeVoto, and Tony Tanner--all dealing with the biography and…

  12. Filmikunsti kolm palet / Andres Maimik

    Index Scriptorium Estoniae

    Maimik, Andres, 1970-

    1999-01-01

    Tallinna filmifestival linastunud mängufilmid "Reekviem" : režissöör Alain Tanner : Šveits - Prantsusmaa - Portugal 1998, "Õnnelikult koos" : režissöör Wong Kar-Wai : Hongkong 1997 ja "Tuntud vana laul" : režissöör Alain Resnais : Prantsusmaa - Šveits - Suurbritannia 1997

  13. Teenagers’ Shape

    Institute of Scientific and Technical Information of China (English)

    亚玲

    2007-01-01

    <正>Teenagers have been of a new shape these days. They are about 20 pounds heavier than teenagers were 60 years ago. They are about four inches taller, too. These facts come from J. M. Tanner, a professor in England.

  14. Predictors of weight loss in Mexican American adolescents

    Science.gov (United States)

    This study examined predictors of weight change in Mexican American adolescents. Eighty overweight Mexican American children were randomized to receive either the intensive intervention or self help program. Physiological (e.g. standardized BMI (zBMI), percent body fat, and tanner stage), psychologi...

  15. EXPLORING THE USE OF SUEDE DYE ON LEATHER

    African Journals Online (AJOL)

    User

    The indigenous leather tanners in Ghana lack access to variety in dyes and colourants, this lim- its the ability of their ... The popular, natural cream colour of leather is the basic colour ... the preparation of the dye from guinea-corn leaves and its ...

  16. Filmikunsti kolm palet / Andres Maimik

    Index Scriptorium Estoniae

    Maimik, Andres, 1970-

    1999-01-01

    Tallinna filmifestival linastunud mängufilmid "Reekviem" : režissöör Alain Tanner : Šveits - Prantsusmaa - Portugal 1998, "Õnnelikult koos" : režissöör Wong Kar-Wai : Hongkong 1997 ja "Tuntud vana laul" : režissöör Alain Resnais : Prantsusmaa - Šveits - Suurbritannia 1997

  17. LONGITUDINAL-STUDY OF BONE-AGE IN ACUTE LYMPHOBLASTIC-LEUKEMIA

    NARCIS (Netherlands)

    TAMMINGA, RYJ; ZWEENS, M; KAMPS, W; DRAYER, N

    1993-01-01

    Bone age was assessed in children with acute lymphoblastic leukaemia (ALL) using the Tanner-Whitehouse II method. X-rays of the left hand (wrist) were made at diagnosis and annually until 5 years after diagnosis. A total of 164 X-rays from 40 patients was available. During treatment bone age develop

  18. A seasonal variation of calcitropic hormones, bone turnover and bone mineral density in early and mid-puberty girls - a cross-sectional study

    DEFF Research Database (Denmark)

    Viljakainen, H.T.; Palssa, A.; Karkkainen, M.

    2006-01-01

    -six girls, mean age 11 center dot 4 (sd 0 center dot 4) years, in Tanner stage 2 (early puberty) and 3 (mid-puberty) were studied during September to March. The BMD was measured from the lumbar vertebrae and the left femur by dual-energy X-ray absoptiometry. Their serum 25-hydroxyvitamin D (S-25-OHD), serum...

  19. Pubertal development and prostate cancer risk

    DEFF Research Database (Denmark)

    Bonilla, Carolina; Lewis, Sarah J; Martin, Richard M

    2016-01-01

    associated with male Tanner stage. A higher score indicated a later puberty onset. We examined the association of this score with prostate cancer risk, stage and grade in the UK-based ProtecT case-control study (n = 2,927), and used the PRACTICAL consortium (n = 43,737) as a replication sample. RESULTS...

  20. Keys of Japanese Prosody and Didactical-Technical Analysis of OJAD (Online Japanese Accent Dictionary)

    Science.gov (United States)

    Delgado Algarra, Emilio José

    2016-01-01

    Most of the studies focus on the teaching of foreign languages indicate that little attention is paid to the prosodic features both didactic materials and teaching-learning processes (Martinsen, Avord and Tanner, 2014). In this context and throughout this article, an analysis of the didactical and technical dimensions of OJAD (Japanese Accent…

  1. Evaluation of the Coastal Features Mapping System for Shoreline Mapping

    Science.gov (United States)

    1991-09-01

    participating in the report preparation included: Ms. Karen Pitchford , Atlantic Research Corporation, who provided technical assistance and helped...40 Tanner, William F., 1978. "Standards for Measuring Shoreline Change", Proceedings of a Workshop, Florida State Univ., 85 pg. Wolf, Paul R., 1983

  2. Coexistence Steady States in a Predator-Prey Model

    CERN Document Server

    Walker, Christoph

    2010-01-01

    An age-structured predator-prey system with diffusion and Holling-Tanner-type nonlinearities is considered. Regarding the intensity of the fertility of the predator as bifurcation parameter, we prove that a branch of positive coexistence steady states bifurcates from the marginal steady state with no prey. A similar result is obtained when the fertility of the prey varies.

  3. Hemoglobinopathies in the Dogon Country: presence of beta S, beta C, and delta A' genes.

    Science.gov (United States)

    Ducrocq, R; Bennani, M; Bellis, G; Baby, M; Traore, K; Nagel, R L; Krishnamoorthy, R; Chaventre, A

    1994-07-01

    The population of the Dogon, located in Mali, is divided in an endogamic Noble class and two endogamic servant castes (Tanners and Blacksmiths). We find that the polymorphic frequencies of beta c, beta S, and, unexpectedly, a mutation of the delta-chain (delta A'), are geographically (valley vs. plateau) as well as social status dependent.

  4. Cooperative Manipulation on the Water Using a Swarm of Autonomous Tugboats

    Science.gov (United States)

    2008-05-01

    Lynch. Locally controllable manipulation by stable pushing. IEEE Transactions on Robotics and Automation, pages 318–327, 1999. [13] R. Murray, Z. Li, and...nipulators. IEEE Transactions on Robotics and Automation, 18(1):94 – 103, 2002. [25] H.G. Tanner, A. Jadbabaie, and G.J. Pappas. Stable flocking of mobile

  5. Suur rahvusvaheline välisbalti arhiivide konverents südasuvises Tartus / Mai Raud-Pähn ; fotod Madis Laas

    Index Scriptorium Estoniae

    Raud-Pähn, Mai, 1920-

    2006-01-01

    Ettekannetega esinesid: Tiiu Kravtsev, Riina Reinvelt, Juta Kivimäe, Piret Noorhani, Merike Kiipus, Anu Korb, Anne Valmas, Mihkel Volt, Mare Rand, Inga Kuljus, Enn Mainla, Roland Weiler, Teas Tanner, Tiina Kirss, Jüri Kivimäe, Enda-Mai Michelson-Holland, Andrae, Carl Göran, Katrin Meerits ja Maie Barrow

  6. 50 CFR 680.3 - Relation to other laws.

    Science.gov (United States)

    2010-10-01

    ....3 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC... governing the conservation and management of king crab and Tanner crab in the BSAI area are contained in 50... requirements using the ADF&G “Intent to Operate” registration form and “Fish Tickets.” (b) Sport, personal...

  7. LONGITUDINAL-STUDY OF BONE-AGE IN ACUTE LYMPHOBLASTIC-LEUKEMIA

    NARCIS (Netherlands)

    TAMMINGA, RYJ; ZWEENS, M; KAMPS, W; DRAYER, N

    1993-01-01

    Bone age was assessed in children with acute lymphoblastic leukaemia (ALL) using the Tanner-Whitehouse II method. X-rays of the left hand (wrist) were made at diagnosis and annually until 5 years after diagnosis. A total of 164 X-rays from 40 patients was available. During treatment bone age

  8. NMR-based metabolomic profiling of overweight adolescents – an elucidation of the effects of inter-/intra-individual differences, gender, pubertal development and physical activity

    DEFF Research Database (Denmark)

    Zheng, Hong; Yde, Christian Clement; Arnberg, Karina

    2014-01-01

    The plasma and urine metabolome of 192 overweight 12-15-year-old adolescents (BMI of 25.4 ± 2.3 kg/m(2)) were examined in order to elucidate gender, pubertal development measured as Tanner stage, physical activity measured as number of steps taken daily, and intra-/interindividual differences aff...

  9. Auditory Pattern Memory: Mechanisms of Tonal Sequence Discrimination by Human Observers

    Science.gov (United States)

    1988-10-30

    and Creelman (1977) in a study of categorical perception. Tanner’s model included a short-term decaying memory for the acoustic input to the system plus...auditory pattern components, J. &Coust. Soc. 91 Am., 76, 1037- 1044. Macmillan, N. A., Kaplan H. L., & Creelman , C. D. (1977). The psychophysics of

  10. Luteinizing Hormone Secretion during Gonadotropin-Releasing Hormone Stimulation Tests in Obese Girls with Central Precocious Puberty

    Science.gov (United States)

    Lee, Hae Sang; Yoon, Jong Seo; Hwang, Jin Soon

    2016-01-01

    Objective: Girls with precocious puberty have high luteinizing hormone (LH) levels and advanced bone age. Obese children enter puberty at earlier ages than do non-obese children. We analyzed the effects of obesity on LH secretion during gonadotropin-releasing hormone (GnRH) tests in girls with precocious puberty. Methods: A total of 981 subjects with idiopathic precocious puberty who had undergone a GnRH stimulation testing between 2008 and 2014 were included in the study. Subjects were divided into three groups based on body mass index (BMI). Auxological data and gonadotropin levels after the GnRH stimulation test were compared. Results: In Tanner stage 2 girls, peak stimulated LH levels on GnRH test were 11.9±7.5, 10.4±6.4, and 9.1±6.1 IU/L among normal-weight, overweight, and obese subjects, respectively (p=0.035 for all comparisons). In Tanner stage 3 girls, peak stimulated LH levels were 14.9±10.9, 12.8±7.9, and 9.6±6.0 IU/L, respectively (p=0.022 for all comparisons). However, in Tanner stage 4 girls, peak stimulated LH levels were not significantly different among normal, overweight, and obese children. On multivariate analysis, BMI standard deviation score was significantly and negatively associated with peak LH (β=-1.178, p=0.001). Conclusion: In girls with central precocious puberty, increased BMI was associated with slightly lower peak stimulated LH levels at early pubertal stages (Tanner stages 2 and 3). This association was not valid in Tanner stage 4 girls. PMID:27215137

  11. Recognition in Britain for CERN personalities

    CERN Multimedia

    2001-01-01

    Sir Chris Llewellyn Smith Lyn Evans British CERN personalities were rewarded for their contribution to physics in this year's prestigious New Year Honours. Chris Llewellyn Smith, Director General from 1994 to 1998, was knighted for services to particle physics. 'The citation, 'for services to particle physics', obviously includes my period at CERN. The honour therefore recognises the work of everyone at CERN, including particularly the contributions of those who worked with me in the Directorate and the Management Board', said Sir Chris. Lyn Evans, Director of the LHC project, was awarded the CBE, Commander of the British Empire, for services to accelerator physics. Erwin Gabathuler, Director of Research from 1981 to 1983 was awarded the OBE, Officer of the British Empire, for services to physics.

  12. CSIR eNews: Biosciences

    CSIR Research Space (South Africa)

    CSIR

    2007-12-01

    Full Text Available development in the world," says Dr Chris Parkinson who leads the CSIR Biosciences discovery chemistry research group of which Van der Westhuyzen and Moleele are members. "The interests of Liotta's research group are well-aligned with our own. Simon, Chris..., Malefa and Pamisha will be exposed to pharmaceutical companies to get an idea about the hard-core end of the research pipeline," says Parkinson, who developed an acquaintance with Liotta in 2003. Together, they have been investigating means to train...

  13. Summary how Google's social network changes everything

    CERN Document Server

    2014-01-01

    This work offers a summary of the book: « Google+ for business: How Google's Social Network Changes Everything » by Chris Brogan.Summary of the ideas in Chris Brogan's book « Google+ for business » highlights that the social network created by Google now has lore than 175 million users and is tied to the largest search engines in the world. Therefore, Google+ could end up being the best online business building tool ever developed. So if you can master using Google+ today, you will be well positioned for what happens in the future as Google, YouTube and others continue to bring new developmen

  14. Human Factors in Web-Authentication

    Science.gov (United States)

    2009-02-06

    69, 70]: Chris Karlof, Umesh Shankar, J.D. Tygar, and David Wagner. “Dynamic Pharming Attacks and Locked Same-origin Policies for Web Browsers.” In...especially grateful to my frequent co-authors, Naveen Sastry and Umesh Shankar. We learned many things together, and I was lucky to have the opportunity to...2009), February 2009. [70] Chris Karlof, Umesh Shankar, J.D. Tygar, and David Wagner. Dynamic Pharming Attacks and Locked Same-origin Policies for Web

  15. Singlid.File under : White American Rock : Sound / Märt Milter

    Index Scriptorium Estoniae

    Milter, Märt

    1998-01-01

    Uutest singlitest : Urban Species "Woman", Cesaria Evora "Sangue De Beirona (remix de Francois K)", Catatonia "Strange Glue", Chris Isaak "Please", Echobeatz "Mas Que Nada", Morcheeba "Blindfold", Chris Rea "Sweet Summer Day", 187 Lockdown "The Don", Bebe Winars "Stay/Thank You", Embrace "My Weakness Is None Of Your Business", Goo Goo Dolls "Iris" ja ameerika popi plaatidest Better Than Ezra "How Does Your Garden Grow?", Barenaked Ladies "Stunt", The Uninvited "The Uninvited, Lilys "Better Can't Make Your Life Better", CIV "Civ", Hootie & The Blowfish "Musical Chairs"

  16. Creating motion graphics with After Effects essential and advanced techniques

    CERN Document Server

    Meyer, Chris

    2010-01-01

    * 5th Edition of best-selling After Effects book by renowned authors Trish and Chris Meyer covers the important updates in After Effects CS4 and CS5 * Covers both essential and advanced techniques, from basic layer manipulation and animation through keying, motion tracking, and color management * Companion DVD is packed with project files for version CS5, source materials, and nearly 200 pages of bonus chapters Trish and Chris Meyer share over 17 years of hard-earned, real-world film and video production experience inside this critically acclaimed text. More than a step-by-step review of th

  17. How to Cheat in Adobe Flash CS5 The Art of Design and Animation

    CERN Document Server

    Georgenes, Chris

    2010-01-01

    Need to solve problems quickly to develop creative projects to time and to budget? Want to hone your Flash skills so you can concentrate on your animation? Then How to Cheat in Flash is for you! Chris Georgenes shows how to work from the problem to the solution - from the viewpoint of an animator who has been commissioned to create a job and is working to a deadline and to a budget. With his in-depth knowledge of the little-known secrets used by the pros to produce creative, professional animations, Chris is the go-to guru for designers and animators who want to create great animation,

  18. Singlid.File under : White American Rock : Sound / Märt Milter

    Index Scriptorium Estoniae

    Milter, Märt

    1998-01-01

    Uutest singlitest : Urban Species "Woman", Cesaria Evora "Sangue De Beirona (remix de Francois K)", Catatonia "Strange Glue", Chris Isaak "Please", Echobeatz "Mas Que Nada", Morcheeba "Blindfold", Chris Rea "Sweet Summer Day", 187 Lockdown "The Don", Bebe Winars "Stay/Thank You", Embrace "My Weakness Is None Of Your Business", Goo Goo Dolls "Iris" ja ameerika popi plaatidest Better Than Ezra "How Does Your Garden Grow?", Barenaked Ladies "Stunt", The Uninvited "The Uninvited, Lilys "Better Can't Make Your Life Better", CIV "Civ", Hootie & The Blowfish "Musical Chairs"

  19. Closed-loop neuromorphic benchmarks

    CSIR Research Space (South Africa)

    Stewart

    2015-11-01

    Full Text Available Benchmarks   Terrence C. Stewart 1* , Travis DeWolf 1 , Ashley Kleinhans 2 , Chris Eliasmith 1   1 University of Waterloo, Canada, 2 Council for Scientific and Industrial Research, South Africa   Submitted to Journal:   Frontiers in Neuroscience   Specialty... the study was exempt from ethical approval procedures.) Did the study presented in the manuscript involve human or animal subjects: No I v i w 1Closed-loop Neuromorphic Benchmarks Terrence C. Stewart 1,∗, Travis DeWolf 1, Ashley Kleinhans 2 and Chris...

  20. 四分钟

    Institute of Scientific and Technical Information of China (English)

    姜米粒

    2008-01-01

    片名:四分钟Vief Minuten(2006) 类别:剧情导演:克里斯·克劳斯Chris Kraus编剧:克里斯·克劳斯Chris Kraus主演:里奇·穆勒Richy Muller莫妮卡·布雷多Monika Bleibtreu汉娜·赫斯普朗Hannah Herzsprung安柏·本加德Amber Bongard获奖情况:2006年上海金爵奖2007年德国劳拉奖

  1. Mitochondrial mutant cells are hypersensitive to ionizing radiation, phleomycin and mitomycin C

    Energy Technology Data Exchange (ETDEWEB)

    Kulkarni, Rohan; Reither, Adrian; Thomas, Robert A. [Department of Biological Sciences, Wayne State University, 5047 Gullen Mall, Suite 1370, Detroit, MI 48202 (United States); Tucker, James D., E-mail: jtucker@biology.biosci.wayne.edu [Department of Biological Sciences, Wayne State University, 5047 Gullen Mall, Suite 1370, Detroit, MI 48202 (United States)

    2009-04-26

    Mitochondrial DNA (mtDNA) is an important contributor to the ATP-generating oxidative phosphorylation complex. Single nucleotide mutations in mitochondrial genes involved in ATP synthesis result in a broad range of diseases. Leber optic atrophy and Leigh's syndrome are two such diseases arising from point mutations in the mitochondrial genome. Here, ionizing radiation, phleomycin and mitomycin C (MMC) were used to induce structural chromosomal aberrations in Leber's and Leigh's cells to investigate how these mitochondrial mutations affect the cell's DNA repair processes. Because of the energy deprivation that results from mitochondrial mutations, we hypothesized that these mutant cells would demonstrate hypersensitivity when exposed to oxidative and genotoxic stress and we also expected that these cells would not be able to repair nuclear DNA damage as efficiently as normal cells. As a consequence, these mutant cells are expected to show increased levels of DNA damage, longer cell cycle delays and increased levels of cell death. Following acute radiation exposure these mutant cells showed an increase in the number of chromosomal aberrations and decreased mitotic indices when compared with normal human lymphoblastoid cells with wild-type mtDNA. When exposed to phleomycin or MMC, the mitochondrial mutant cells again showed hypersensitivity and decreased mitotic indices compared to normal cells. These results suggest that Leber's and Leigh's cells have an impaired ability to cope with oxidative and genotoxic stress. These observations may help explain the role of ATP generation in understanding the enhanced sensitivity of mitochondrial mutant cells to cancer therapeutic agents and to adverse environmental exposure, suggesting that individuals with mtDNA mutations may be at a greater risk for cancer and other diseases that result from an accumulation of nuclear DNA damage.

  2. {sup 1}H MR spectroscopy of the basal ganglia in childhood: a semiquantitative analysis

    Energy Technology Data Exchange (ETDEWEB)

    Lam, W.W.M. [Chinese Univ. of Hong Kong, Hong Kong (China). Dept. of Diagnostic Radiol. and Organ Imaging; Wang, Z.J.; Bilaniuk, L.T.; Hunter, J.V.; Haselgrove, J.C.; Zimmermann, R.A. [Department of Radiology, The Children`s Hospital of Philadelphia, 34th St. and Civic Center Blvd., Philadelphia, PA 19104 (United States); Zhao, H. [Division of Biostatistics and Epidemiology, The Children`s Hospital of Philadelphia, Philadelphia, Pennsylvania (United States); Berry, G.T.; Kaplan, P.; Gibson, J. [Division of Metabolism, The Children`s Hospital of Philadelphia, Philadelphia, Pennsylvania (United States); Kaplan, B.S. [Division of Nephrology, The Children`s Hospital of Philadelphia, Philadelphia, Pennsylvania (United States)

    1998-05-01

    Proton MR spectra of the basal ganglia were obtained from 28 patients, 24 male and 14 female, median age 16.3 months (5 weeks to 31 years). They included 17 patients with normal MRI of the basal ganglia without metabolic disturbance (control group) and 11 patients with various metabolic diseases: one case each of high serum sodium and high serum osmolarity, cobalamin C deficiency, Leigh disease, Galloway-Mowat syndrome, Pelizaeus-Merzbacher disease, hemolytic-uremic syndrome and Wilson disease and two cases of Alagille syndrome and methylmalonic acidemia with abnormal MRI of the basal ganglia or blood or urine analysis (abnormal group). The MR spectrum was measured by using STEAM. The MR-visible water content of the region of interest was obtained. Levels of myoinositol, choline, creatine and N -acetylaspartate were measured using a semiquantitative approach, with absolute reference calibration. In the control group, there was a gradual drop of water content over the first year of life; N -acetylaspartate, creatine and myoinositol levels showed no significant change with age, in contrast to the occipital, parietal and cerebellar regions. Choline showed a gradual decrease for the first 2 years of life and then remained fairly constant. In the abnormal group the water content was not significantly different. N -Acetylaspartate was decreased in patients with high serum sodium and high serum osmolarity, cobalamin C deficiency, Leigh disease and one case of methylmalonic acidemia. Decreased creatine was also found in Leigh disease, and decreased choline in Galloway-Mowat syndrome and Wilson disease. Myoinositol was elevated in the patient with abnormally high serum sodium, and decreased in the hemolytic-uremic syndrome. (orig.) With 3 figs., 4 tabs., 35 refs.

  3. Abréviations

    OpenAIRE

    2014-01-01

    AJJR Annales de la Société Jean-Jacques Rousseau, Genève, A. Jullien, puis Droz, 1905-. CC Correspondance complète, Ralph A. Leigh éd., Genève-Oxford, Institut et musée Voltaire - Voltaire Foundation, 1965-1991, 50 volumes. Confessions Les Confessions de Jean-Jacques Rousseau, Œuvres complètes, t. I, Raymond Trousson éd., Paris, Honoré Champion, 2012. DJJR Dictionnaire Jean-Jacques Rousseau, Raymond Trousson et Frédéric S. Eigeldinger dir., Paris, Honoré Champion, 1996. EJJR Études Jean-Jacqu...

  4. A novel mitochondrial mutation m.8989G>C associated with neuropathy, ataxia, retinitis pigmentosa - the NARP syndrome.

    Science.gov (United States)

    Duno, Morten; Wibrand, Flemming; Baggesen, Kirsten; Rosenberg, Thomas; Kjaer, Niels; Frederiksen, Anja L

    2013-02-25

    The archetypal NARP syndrome is almost exclusively associated with the m.8993T>C/G mutation in the sixth subunit of the mitochondrial ATP synthase, whereas other mutations in the MT-ATP6 gene primarily associate with Leigh syndrome or Leber's hereditary optic neuropathy (LHON). We report a novel mitochondrial point mutation, m.8989G>C, in a patient presenting with neuropathy, ataxia and retinitis pigmentosa constituting the classical NARP phenotype. This mutation alters the amino acid right next to canonical NARP mutation. We suggest that classic NARP syndrome relates to a defined dysfunction of p.MT-ATP6.

  5. Whole exome sequencing reveals compound heterozygous mutations in SLC19A3 causing biotin-thiamine responsive basal ganglia disease

    Directory of Open Access Journals (Sweden)

    L.J. Sremba

    2014-01-01

    Full Text Available Biotin-thiamine responsive basal ganglia disease (BTBGD is a rare metabolic condition caused by mutations in the SLC19A3 gene. BTBGD presents with encephalopathy and significant disease progression when not treated with biotin and/or thiamine. We present a patient of Mexican and European ancestry diagnosed with BTBGD found to have compound heterozygous frameshift mutations, one novel. Our report adds to the genotype-phenotype correlation, highlighting the clinical importance of considering SLC19A3 gene defects as part of the differential diagnosis for Leigh syndrome.

  6. Et in Arcadia Eco: Law & Masonic Literature

    OpenAIRE

    Chakmakjian, Pauline

    2013-01-01

    This paper explores how Umberto Eco’s novel Foucault’s Pendulum can be interpreted as a critical parody of The Holy Blood and The Holy Grail by the historians Baigent, Leigh and Lincoln respectively. We explore why two of these authors chose Dan Brown’s novel The Da Vinci Code as the object of their copyright grievance when Eco’s work was at least potentially an equal case. Especially since Eco’s work is frequently referred to as ‘the thinking man’s Da Vinci Code.’ First, we have analyzed the...

  7. "Et in Arcadia Eco: Law & Masonic Literature"

    OpenAIRE

    Pauline Chakmakjian

    2013-01-01

    Este trabajo explora como la novela de Umberto Ecco,El péndulo de Foucault, pudo haber sido interpretada como unaparodia deHoly Blood and Holy Grailpor sus autores, Baigent y Leigh. Exploramos porqué Baigent y Leigheligieron llevar a juicio la novela de Dan Brown “El Codigo Da Vinci” cuando la obra de Foucault era un casoparecido. Especialmente porque la obra de Eco es conocida como “El código Da Vinci del hombre que piensa”.Primero, hemos analizado la proximidad de las estructuras de la nove...

  8. "Et in Arcadia Eco: Law & Masonic Literature"

    OpenAIRE

    Pauline Chakmakjian

    2013-01-01

    Este trabajo explora como la novela de Umberto Ecco,El péndulo de Foucault, pudo haber sido interpretada como unaparodia deHoly Blood and Holy Grailpor sus autores, Baigent y Leigh. Exploramos porqué Baigent y Leigheligieron llevar a juicio la novela de Dan Brown “El Codigo Da Vinci” cuando la obra de Foucault era un casoparecido. Especialmente porque la obra de Eco es conocida como “El código Da Vinci del hombre que piensa”.Primero, hemos analizado la proximidad de las estructuras de la nove...

  9. Et in Arcadia Eco: Law & Masonic Literature

    OpenAIRE

    Chakmakjian, Pauline

    2013-01-01

    This paper explores how Umberto Eco’s novel Foucault’s Pendulum can be interpreted as a critical parody of The Holy Blood and The Holy Grail by the historians Baigent, Leigh and Lincoln respectively. We explore why two of these authors chose Dan Brown’s novel The Da Vinci Code as the object of their copyright grievance when Eco’s work was at least potentially an equal case. Especially since Eco’s work is frequently referred to as ‘the thinking man’s Da Vinci Code.’ First, we have analyzed the...

  10. Hamiltonian YM 2+1: note on point splitting regularization

    CERN Document Server

    Schulz, Hermann

    2016-01-01

    The Hamiltonian of 2+1 dimensional Yang Mills theory was derived by Karabali, Kim and Nair by using point splitting regularization. But in calculating e.g. the vacuum wave functional this scheme was left in favour of arguments. Here we follow up a conjecture of Leigh, Minic and Yelnikov of how this gap might be filled by including all positive powers of the regularization parameter ($\\ep \\to +0$). Admittedly, though we concentrate on the ground state in the large $N$ limit, only two such powers could be included due to the increasing complexity of the task.

  11. 商品真实性的社会建构

    Institute of Scientific and Technical Information of China (English)

    邓永成

    2010-01-01

    Brown(2001)指出,事实上,现代营销的核心主题之一就是真实(Authenticity)与不真实之间的运动(tension)。一些学者们则认为,真实性是现代营销的基石(Michael B.Beverland,Adam Lindgreen,Michiel W.Vink(2008)。“真实性”问题已成为营销文献中重要课题(Thomas W.Leigh Cara Peters Jeremy Shskon 2006)。

  12. Contrastes, paradojas y exclusiones en torno al aborto. Una lectura posible de Asunto de mujeres y El secreto de Vera Drake

    OpenAIRE

    Jiménez Lucena, Isabel

    2011-01-01

    En este trabajo se trata de poner de manifiesto las distintas maneras en que se ha planteado en el cine un tema socialmente polémico como el aborto, y cuáles son los efectos que esos diferentes abordajes pueden tener en el espectador. Para ello se analizan dos películas que fueron muy reconocidas por la crítica como son Asunto de Mujeres/ Une affaire de femmes (1988) de Claude Chabrol y El secreto de Vera Drake/ Vera Drake (2004) de Michael Leigh. Se ha analizado especialmente las...

  13. From Poet to Poet or Shelley’s Inconsistencies in Keats’s Panegyric: Adonais as an Autobiographical Work of Art

    Directory of Open Access Journals (Sweden)

    Caroline BERTONÈCHE

    2007-06-01

    Full Text Available Adonais, in short, is such an elegy as poet might be expected to write upon poet. The author has had before him his recollections of Lycidas, of Moschus and Bion, and of the doctrines of Plato; and in the stanza of the most poetical of poets, Spenser, has brought his own genius, in all its ethereal beauty, to lead a pomp of Loves, Graces, and Intelligences, in honour of the departed. (Leigh Hunt, “Unsigned Review of Adonais”, The Examiner, 7 juillet 1822I have engaged these last days in comp...

  14. Lifetime history of indoor tanning in young people: a retrospective assessment of initiation, persistence, and correlates

    Directory of Open Access Journals (Sweden)

    Lostritto Karen

    2012-02-01

    Full Text Available Abstract Background Despite educational and public health campaigns to convey the risks of indoor tanning, many individuals around the world continue to engage in this behavior. Few descriptive studies of indoor tanning have collected information pertaining to the lifetime history of indoor tanning, thereby limiting our ability to understand indoor tanning patterns and potentially target interventions for individuals who not only initiate, but continue to persistently engage in indoor tanning. Methods In-person interviews elicited detailed retrospective information on lifetime history of indoor tanning among white individuals (n = 401 under age 40 seen by a dermatologist for a minor benign skin condition. These individuals were controls in a case-control study of early-onset basal cell carcinoma. Outcomes of interest included ever indoor tanning in both males and females, as well as persistent indoor tanning in females - defined as females over age 31 who tanned indoors at least once in the last three or all four of four specified age periods (ages 11-15, 16-20, 21-30 and 31 or older. Multivariate logistic regression was used to identify sociodemographic and lifestyle correlates of ever and persistent indoor tanning in females. Results Approximately three-quarters (73.3% of females and 38.3% of males ever tanned indoors, with a median age of initiation of 17.0 and 21.5, respectively. Among indoor tanners, 39.3% of females and 21.7% of males reported being burned while indoor tanning. Female ever indoor tanners were younger, had darker color eyes, and sunbathed more frequently than females who never tanned indoors. Using unique lifetime exposure data, 24.7% of female indoor tanners 31 and older persistently tanned indoors starting as teenagers. Female persistent indoor tanners drank significantly more alcohol, were less educated, had skin that tanned with prolonged sun exposure, and sunbathed outdoors more frequently than non-persistent tanners

  15. "Sekretnõje materialõ" zhdite potseluja / Jekaterina Zhivova

    Index Scriptorium Estoniae

    Zhivova, Jekaterina

    2008-01-01

    USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

  16. Täiesti salatised toimikud nostalgiakastmes / Mart Niineste

    Index Scriptorium Estoniae

    Niineste, Mart, 1983-

    2008-01-01

    USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

  17. X-Files opjat v stroju

    Index Scriptorium Estoniae

    2008-01-01

    USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

  18. Uuesti avatud salatoimikud / Timo Diener

    Index Scriptorium Estoniae

    Diener, Timo

    2008-01-01

    USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

  19. Salatoimikud : ma tahan uskuda / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2008-01-01

    USA sarjale "The X-Files" põhinev teine järjefilm "Salatoimikud: Ma tahan uskuda" ("The X-Files: I Want to Believe") : režissöör Chris Carter : peaosades David Duchovny, Gillian Anderson : Ameerika Ühendriigid - Kanada 2008

  20. Earth Science: It's All about the Processes

    Science.gov (United States)

    King, Chris

    2013-01-01

    Readers of the draft new English primary science curriculum (DfE, 2012) might be concerned to see that there is much more detail on the Earth science content than previously in the United Kingdom. In this article, Chris King, a professor of Earth Science Education at Keele University and Director of the Earth Science Education Unit (ESEU),…

  1. Reclaiming Our Roots: The Influences of Media Curriculum on the Natural Hair Movement

    Science.gov (United States)

    Jeffries, Rhonda Baynes; Jeffries, Devair

    2014-01-01

    This article, theoretically constructed on Gramsci's notion of cultural hegemony, explores the use of Black female hair as a cultural signifier in two media texts, specifically Adrienne Kennedy's play, "Funnyhouse of a Negro," and Chris Rock's documentary, "Good Hair," in specific media texts. Analysis of the…

  2. Modularly Integrated MEMS Technology

    Science.gov (United States)

    2006-05-23

    underrepresented minorities students that I’ve befriended over the years. This includes: Sheila Humphrey , Megan Thomas, Chris Hildrum, Tiffany Grant...fabrication using photoresist-ashing technique,” IEEE Electron Device Letters, Vol.9, p.3248-3251, 1996. [4.11] B. Doris , M. Ieong, T. Kanarsky, Y

  3. A Healing Vision.

    Science.gov (United States)

    Davis, Terry

    1996-01-01

    Suggests that Chris Crutcher, therapist and author of novels for young adults, views the world as a place where God, if He exists, does not prevent or cause good or bad things to happen to people. Suggests that Crutcher sees the human spirit as the ultimate determinant along with human relationships. (TB)

  4. Püha sõda brittide koduhoovis / Laurence Boyce

    Index Scriptorium Estoniae

    Boyce, Laurence

    2010-01-01

    Artikli autor räägib oma mõtetest: 2005. aasta 8. juulil korraldasid Leedsist pärit terroristid Londoni metroos ja bussis terroriaktid. Ka briti raadio- ja telesatiiriku Chris Morrise terrorismikomöödiast "Neli lõvi" (Suurbritannia 2010)

  5. 'You get out what you put in'.

    Science.gov (United States)

    2017-03-01

    Chris O'Connor trained at the Nightingale School of Nursing at St Thomas' Hospital in London, qualifying as a mental health nurse in 1993. He worked in acute psychiatry, and learning disabilities and older people's services, before becoming head of nursing practice for a London mental health trust. His current role is nurse consultant for dementia and older people at East Surrey Hospital.

  6. Practices, Virtue Ethics, and Music Education

    Science.gov (United States)

    Bowman, Wayne

    2012-01-01

    Music education is generally equated with the act of teaching music. In "The Good Life of Teaching: An Ethics of Professional Practice," the remarkable book that orients the essays in this issue of "Action, Criticism, and Theory for Music Education," Chris Higgins argues, among other things, that the view of teaching as a helping profession--one…

  7. The Virtuous, Wise, and Knowledgeable Teacher: Living the Good Life as a Professional Practitioner

    Science.gov (United States)

    Campbell, Elizabeth

    2013-01-01

    In this essay, Elizabeth Campbell reviews three recent books that address the ethical nature of professional practice: "Knowledge and Virtue in Teaching and Learning: The Primacy of Dispositions," by Hugh Sockett; "The Good Life of Teaching: An Ethics of Professional Practice," by Chris Higgins; and "Towards Professional…

  8. Le LEP sera encore là en l'an 2000

    CERN Multimedia

    CERN Press Office. Geneva

    1998-01-01

    CERN's Large Electron-Positron collider got the green light today to achieve its full potential by running for an additional year in the year 2000. Delegates attending the 110th meeting of the Laboratory's governing body, Council, approved the move after a careful presentation of the proposal's scientific merits and financial aspects by CERN's Director General Chris Llewellyn Smith.

  9. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (77th, Atlanta, Georgia, August 10-13, 1994). Part IX: Magazines.

    Science.gov (United States)

    Association for Education in Journalism and Mass Communication.

    The Magazines section of this collection of conference presentations contains the following 15 papers: "'National Geographic Magazine' and the Vietnam War: Did We Just Get Pretty Pictures?" (John W. Williams); "Free Speech at All Costs: A Short History of 'The Masses'" (Chris Lamb); "Newspapers Locally Edited Magazines…

  10. Harry Potteri film jõudis Eestisse / Ilona Martson

    Index Scriptorium Estoniae

    Martson, Ilona, 1970-

    2001-01-01

    Joanne Rowling'u lasteraamatu "Harry Potter ja Tarkade kivi" ekraniseeringu esilinastus Eestis on 21. detsembril Coca Cola Plazas. Selle 125 miljonit dollarit maksnud USA filmi režissöör on Chris Columbus ja peaosas 12-aastane Daniel Radcliff

  11. Dynamics of Supercritical Flows

    Science.gov (United States)

    2012-08-26

    appreciated. I would like to recognize current and former lab colleagues including Juliett, Juan, Chris, Dan, Cory, Lord, Jeff, Kevin , Hann-Shin, Alec, Ian...long wooden planks treated with water-resistant paint and one 0.5m long acrylic hollow plate with a blunt trailing edge. The wood was placed upstream

  12. Ühest poisist : film ja raamat / Ene Vainik

    Index Scriptorium Estoniae

    Vainik, Ene

    2002-01-01

    Mängufilm "Suur poiss ja väike poiss" ("About a Boy") : režissöörid Paul ja Chris Weitz : Suurbritannia - Ameerika Ühendriigid - Prantsusmaa 2002. Võrdlus filmi ja selle aluseks olnud Nick Hornby romaani "Ühest poisist" vahel

  13. 78 FR 65163 - Airworthiness Directives; Sikorsky Aircraft Corporation-Manufactured (Sikorsky) Model Helicopters...

    Science.gov (United States)

    2013-10-31

    ... Corporation- Manufactured (Sikorsky) Model Helicopters (Type Certificate Currently Held by Erickson Air-Crane... helicopters (type certificate currently held by Erickson Air-Crane Incorporated (Erickson)). AD 97-19-10..., contact Erickson Air-Crane Incorporated, ATTN: Chris Erickson, Director of Regulatory Compliance, 3100...

  14. 78 FR 15599 - Airworthiness Directives; Sikorsky Aircraft-Manufactured Model S-64F Helicopters

    Science.gov (United States)

    2013-03-12

    ... Model S-64F helicopters, now under the Erickson Air-Crane Incorporated (Erickson) Model S-64F type... service information identified in this AD, contact Erickson Air-Crane Incorporated, ATTN: Chris Erickson... Model S-64F helicopters, now under the Erickson Air-Crane Incorporated Model S-64F type certificate...

  15. DVD-d. Shrek Kolmas; Ma olen legend / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2008-01-01

    Lühiarvustused USA 2007.a. filmidele : animafilm "Shrek Kolmas" ("Shrek the Third", režissöörid Chris Miller, Raman Hui) ja ulmefilm "Ma olen legend" ("I Am Legend"; režissöör Francis Lawrence)

  16. JeS zhdjot ot Rossii podtverzhdenija / Marko Saaret

    Index Scriptorium Estoniae

    Saaret, Marko

    2004-01-01

    Euroopa Komisjoni president Romano Prodi, välisasjade komissar Chris Patten ja kaubandusvolinik Pascal Lamy alustavad visiiti Moskvasse. Venemaalt oodatakse lõplikku kinnitust kirjutamaks alla partnerluse ja koostöö lepingu laienemisele uute EL-i riikidega enne 1. maid

  17. Plaadisoovitus

    Index Scriptorium Estoniae

    2006-01-01

    Uutest heliplaatidest dieter Bohlen "Dieter", Neil Young "Living With War", "Hip Hop IV", Chris Isaak "Best Of", Tom Jones "Graetest Hits", juanes "Mi Sangre", The Poison "Bullet For My Valentine", "Metal For Masses", Pet Shop Boys "Fundamental", Prince "3121", gnarls Barkley "St Elsewhere" Hoobastank "Every Man For Himself"

  18. Aesthetic Relationships and Ethics in "The Oh Fuck Moment"

    Science.gov (United States)

    Breel, Astrid

    2015-01-01

    This article explores the aesthetics and ethics of participatory performance through "The Oh Fuck Moment" by Hannah Jane Walker and Chris Thorpe, a performance that aesthetically explores ethically troubling material and manipulation. Ethical criticism of participatory art in recent years has focused on the way the audience member is…

  19. Witnessing the World: The Power of True Global Service

    Science.gov (United States)

    Piccone, Chris

    2013-01-01

    The school where Chris Piccone teaches eighth-grade English maintains a desire to pull its community from its comfort zones to experience first hand the crushing poverty in the Dominican Republic. Although he always thought of himself as a bleeding heart, who was proud that he pushed his students out of their academic comfort zones, he realized…

  20. Rotary jagas stipendiume

    Index Scriptorium Estoniae

    2009-01-01

    Pärnu Rotary klubi aastapäevapeol 11. mail Ammende villas anti stipendium viiele Pärnumaa noorele, teiste seas pälvis preemia Pärnu Ülejõe Gümnaasiumi muusikaõpetaja Fred Rõigas ja Pärnu Muusikakoolis trompetit õppiv Chris Sommer