WorldWideScience

Sample records for chobiryo kagaku busshitsu

  1. Fiscal 1997 report on the results of the international standardization R and D. Measurement of ultra-micro chemical substances and measuring methods of hormone effects; 1997 nendo seika hokokusho kokusai hyojun soseigata kenkyu kaihatsu. Chobiryo kagaku busshitsu no keisoku horumon eikyo sayo sokuteiho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Concerning the measurement system of ultra-micro hazardous chemical substances in the global environment, the paper examined the present situation of chemical substances such as dioxins, made an experimental study on the method to analyze dioxins in exhaust gas from an aspect of international consistency, and worked out a JIS draft. As to the standard measuring method of hormone effects of chemical substances, the paper developed the competitive bonding experiment system to measure bonding ability of chemical substances to homo sapiens estrogen receptor (ER). By measuring ER bonding ability of 78 kinds of chemical substances, the measuring method was developed. In the development of the assay system for detection of hormone-like compounds, the assay system with transfer activity via estrogen receptor as an index was established using cultured cells and yeast. Further, the development was made of a measuring method of receptor bonding activity of hormone-like substances. 33 refs., 151 figs., 66 tabs.

  2. Indoor air pollution by chemical substances; Kagaku busshitsu ni yoru shitsunai kuki osen

    Energy Technology Data Exchange (ETDEWEB)

    Matsumura, T. [National Institute of Hygienic Sciences, Tokyo (Japan)

    1995-07-31

    The economy in our country entered the high growth period in the 1960,s, and specially the chemical industry based on fossil fuel brought about raped development. This was accompanied by widespread amicability of construction materials and household articles made from chemical substances in offices and households. As a results of the first oil crisis in 1973, energy conservation has since been intended, particularly the amount of ventilation in the office was reduced to about 1/3-1/4 of that in Europe and America. Accordingly, many working people in office have complained of various symptoms such as headache and dizziness. It subsequently became clear that the causes were hazardous pollutants in the room. From the above point of view, we focused on air pollution in terms of chemical substances in the room(office and living environment) in this paper. We introduce the present state of air pollution in the room with reference to the results of our studies and literature inside and outside the country. 35 refs., 10 tabs.

  3. Local sensing of biological substances by scanning electrochemical microscopy; Sosagata denki kagaku kenbikyo ni yoru seitai busshitsu no kyokusho sensing

    Energy Technology Data Exchange (ETDEWEB)

    Saito, T. [Tokyo College of Pharmacy, Tokyo (Japan)

    1999-01-01

    This paper describes a method for local detection of biological substances by using a scanning electrochemical microscope (SECM). The electrochemical detection method is a multipurpose analysis method that can quantify substances in aqueous solution on a real time basis. A micro electrode has made a debut recently and become applied to local zones in biological structures and cells. Capturing surface structures and compositions of substances have become possible with the SECM using the micro electrode as a probe, as does the probe of a scanning tunnel electron microscope (STM). While the STM can recognize microfine structures of smaller than 1 nm, the SECM does it only on {mu} level, but can measure a variety of living organisms as the recognition is possible in aqueous solutions. Antigens are reacted with antibodies on spots of several ten {mu} m oriented on a glass substrate, where oxidizing and reducing reactions by peroxidaze modified on the antibodies are read on the SECM, making quantification of the antibodies possible. Chemical treatment of enzymes and antibodies can also be performed onto the glass substrate by using this micro electrode. Expectation is placed on providing living organism information in multi items and multi dimensions. (NEDO)

  4. Recent situation related to drinking water quality management; Suidosuishitsu kanri wo meguru saikin no doko (Kagaku busshitsu, byogensei biseibutsu taisaku wo chushin to shite)

    Energy Technology Data Exchange (ETDEWEB)

    Arai, S. [Ministry of health and Welfare, Tokyo (Japan)

    2000-06-05

    Recent situation related to drinking water quality management, including designation of dioxins as Monitoring Items of waterworks, measures against drinking water pollution by Cryptosporidium, research of endocrine disrupters in drinking water such as phthalates, maintenance of reserve tanks, and decentralization and deregulation of administrative systems, is introduced. Discussions on the future regulation and/or management measure of drinking water at the Living Environment Council is also introduced. (author)

  5. Fiscal 2000 research and development of technologies for intelligent infrastructure creation and utilization. Research and development of reference materials relating to endocrine disrupting chemicals (Studies of storage stability, methods of implantation, etc., for pure substance standard, mixed substance standard, and composition type standard); 2000 nendo chiteki kiban sose riyo gijutsu kenkyu kaihatsu. Naibunpi kakuran kagaku busshitsu kanren hyojun busshitsu no kenkyu kaihatsu (Jun busshitsu hyojun, kongo hyojun oyobi soseigata hyojun busshitsu ni kakawaru hozon anteisei, netsuke hoho nado)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Environmental pollution by endocrine disrupters is a formidable threat to environmental safety because it involves the basic living circumstances of organisms and will stay dangerous through the generations. Disrupting chemicals found firstly in polymeric materials are also detected in aqueous beings' living environments such as water and river bottom. In this fiscal year, out of reference materials deemed to be necessary for the measurement of endocrine disrupters, butylbenzyl phthalate, 4-t-butylphenol, 4-n-heptylphenol, and 4-t-octylphenol were taken up for the determination of reference material purity, establishment of methods for preparing standard solutions, establishment of methods for determining standard solution concentration, and the evaluation of standard solution storage stability. Moreover, a method for determining concentration was established and storage stability was evaluated for a mixed standard liquid which was a mixture of the 4 phtalate esters. As the result, a standard solution accurate in concentration and excellent in storage stability was developed. (NEDO)

  6. Risk communication about chemical substance. Case studies in communication under guidelines established by local autonomies and trend of information sources; Kagaku busshitsu ni kansuru risuku komyunikeshon. Jichitai seitei no shishin ni motozuku komyunikeshon jirei to johogen no doko

    Energy Technology Data Exchange (ETDEWEB)

    Yoshimi, H. [Kanagawa Environmental Research Center, Kanagawa (Japan)

    1995-01-10

    Actions and measures is left to local autonomies, to chemical substances that are in commercial markets and are out of national regulations for their emission and disposal, even though they have public concerns for environmental effects. Thus, a trend to establish guidelines to prevent pollution by those chemicals has been spreading among autonomies facing actions and measures to them. Present status and problems are explained, of the guideline establishment and communication between autonomies and citizens or business owners to promote their self-management according to guidelines. Further, recent trends are introduced, of information sources on chemical substances that serve as a base of the communication. Guidelines of some prefectures ask business owners to collect information on substances that they deal with and needs environmental attention, by a format mimicking to MSDS (Material Safety Data Sheet). On the other hands, other guidelines stipulate that prefectures should provide business owners with information in forms of data-book, off-line or on-line data-base to aid them to collect information. Some guidelines stipulate to settle agreements or to organize councils on environmental safety. 6 refs., 2 figs., 1 tab.

  7. Report on achievements in fiscal 1999 on the project for research and development of an intellectual base creating and utilizing technology. Research and development operation on developing a standard substance for surface chemical analysis; 1999 nendo hyomen kagaku bunseki hyojun busshitsu kaihatsu ni kansuru kenkyu kaihatsu gyomu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A silicon standard substance using boron as an impurity whose quantity has been controlled was prepared as a standard substance for secondary ion-mass spectrography (SIMS), and given an evaluation test. Boron used for addition was prepared in three levels in the concentration range from 10{sup 16} atoms/cm{sup 3} to 10{sup 18} atoms/cm{sup 3}. On both of epitaxial silicon and bulk silicon crystals, the concentration variation in the added boron was suppressed to {+-} 5% or less of the targeted value in the area of wafer center {+-} 30 mm, and verified of the uniformity satisfying the specifications as the standard substance. Standard methods were established on the concentration measurement by using the SIMS and the concentration calibration on boron added uniformly into silicon. Concentrations were determined with variance of about {+-} 10% on boron with medium concentration (10{sup 17} atoms/cm{sup 3}) and high concentration (10{sup 18} atoms/cm{sup 3}) through a round-robin test. Thus, it was made possible to provide boron to the standard substance, and the target for sample preparation was achieved. The silicon standard substance requested by ISO14237 can now be provided, opening the way for registration in the future in Japan as the certified standard substance. (NEDO)

  8. Micro-chemistry. New current in chemistry; Maikuro kagaku. Kagaku no atarashii choryu

    Energy Technology Data Exchange (ETDEWEB)

    Masuhara, H. [Osaka University, Osaka (Japan). Faculty of Engineering

    1994-06-01

    In achieving artificial reaction in micrometer orders as in reactions in cells of living organisms, several results have been obtained in its specific methods. These results lead to an expectation on search and elucidation of new chemical phenomena, and development to structuring micro-chemical systems. This paper illustrates the basic conception thereof, and a large number of examples of the methods. Researches on the methods may be represented by a large number of results as follows: a position with as high reactivity as 3 {mu} meters in resolution has been utilized by utilizing the fact that such reaction intermediates as radicals and ions are produced with long life during laser explosion and erosion of polymers, for example; micro selective growth of CVD thin films was realized by using a lithographic method; developing an electrochemical reaction only beneath a chip under an scanning electrochemical microscope has produced successfully a space distribution of 0.5 {mu} meter in a reaction product; and optic-chemical processing of microfine particles and micro time analysis were performed successfully. 1 ref., 5 figs.

  9. Marine resources chemistry of magnesium. Magnesium no kaiyo shigen kagaku

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-18

    Marine water body covers 71% of the earth surface, and has an average depth of about 3700 m. This huge marine water body contains magnesium of 1300 ppm on average in its water. This paper describes research and development related to high-purity sea water magnesium oxide that could be produced from these marine resources. Effects of impurities in sea water, particularly removal of calcium and boron are the important subject for studying high-purity sea water magnesium oxide. This paper describes results of developing a decarbonation pretreatment method for reducing calcium impurities and an alkaline method to reduce boron impurities. Most methods of manufacturing magnesium from sea water in an industrial scale change magnesium hydroxide precipitated from sea water into MgCl2, and electrolyze it to obtain metallic magnesium. The paper shows results of the development of a method to recover magnesium hydroxide and basic magnesium carbonate using the lime-ammonium circulation process that uses salt making bittern as a raw material. 6 refs., 7 figs.

  10. Space environment utilization and chemical engineering; Uchu kankyo riyo to kagaku kogaku

    Energy Technology Data Exchange (ETDEWEB)

    Imaishi, N.; Shiraishi, F. [Kyushu Univ., Fukuoka (Japan)] Suzuki, M. [Tohoku Univ., Sendai (Japan)

    1997-10-05

    Construction of a giant international space station on an orbit of 460 km distant from the earth will be begun since 1998, JEM (Japanese Experimental Module) will also be launched on 2001, and various experiments using the space environment under a condition of staying 2 to 4 members in the JEM will be planned after the end of that year. Characteristics of the space environment are microgravity, super high vacuum at surrounding apace, superior vision and so forth. In order to utilize the space environment different from the earth environment, it is necessary to consider extremely many things. The chemical engineers who have conducted a lot of complex systems on the earth hitherto shares some large roles in the fields of planning and executing scientific and engineering researches conducted in JEM, utilization of lunar surface and space for materials and energy production base in future, and so forth. In this paper, the Closed Ecological Life Support system (CELSS) essential to specific phenomena and long-term manned space flight under microgravity environment were introduced. 29 refs., 7 figs.

  11. Process improvement technology for petrochemical plant; Sekiyu kagaku puranto ni okesu purosesu kaizen gijutsu

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, Shin

    1999-05-05

    Before, GTC technology Co. was a manufacturer of the tray as a Greenwich technology. It is the subsidiary, which undertakes technology and licence of the engineering firm in U.S.A. at present. It carries out besides the technology licence support in the startup for the prolonged driving of technical service, operating condition of the plant of improvement and optimization and, etc. Has made separation and purification technology, which made extractive distillation to be a beginning good and has the process improvement technology to the PTA (high-pure terephthalic acid) from BTX (benzene toluene xylene) of petrochemical plant. (NEDO)

  12. Microalgal biotechnologies for recycling of pollutants; Tayona sorui kino wo kiban to suru seibutsuken busshitsu junkangata sogo saishigenka gijutsu

    Energy Technology Data Exchange (ETDEWEB)

    Miyamoto, K.; Nasu, M.; Hashimoto, C.; Tanaka, K.; Hirata, M. [Osaka University, Osaka (Japan). Faculty of Pharmaceutial Science; Fujita, M.; Takagi, M. [Osaka University, Osaka (Japan). Faculty of Engineering; Hirata, Y.; Taya, M. [Osaka University, Osaka (Japan). Faculty of Engineering Science; Yamanishi, H. [Osaka University, Osaka (Japan). Faculty of Medicine

    1997-02-01

    This paper describes the technology development by which biomass is produced by treatment of pollutants using microalgae, and is recycled. A bioreactor system has been developed, in which microalgal biomass can be obtained through the effective treatment of CO2 and NOx using microalgae having ability of increase under the severe condition with simultaneous flow of CO2 and NOx. A new method has been also developed for separating and recovering the microalgae. Materials, such as glucose, glycerol, acetic acid, and lactic acid, were produced from the obtained biomass through physico-chemical and biological treatments. These materials can be converted into ethanol and hydrogen. For this treatment and recycling system, functions as a part of natural material recycling were considered to be most significant. Development of an analysis and evaluation method of an impact of this system on the natural environment is also tried. 1 fig.

  13. Coal Liquefaction characteristics and chemical structure of product oil; Sekitan ekika hanno tokusei to seiseibutsu no kagaku kozo

    Energy Technology Data Exchange (ETDEWEB)

    Endo, H.; Sato, M.; Chiba, T.; Hattori, H. [Hokkaido University, Sapporo (Japan). Center for Advanced Research of Energy Technology; Sasaki, M. [Hokkaido National Industrial Research Institute, Sapporo (Japan)

    1996-10-28

    Through the hydrogenolysis of Wandoan coal and Tanito Harum coal which are used for the NEDOL process, differences of liquefaction characteristics between them were found. The purpose of this study is to grasp these differences as differences of chemical structures of oil fractions. The compound type analysis was conducted for oil fractions obtained at varied reaction temperature for varied reaction time. Coal liquefaction characteristics of these coals were discussed by relating oil yields and chemical structures. For Tanito Harum coal, yields of gas and oil were considered to be lower than those for Wandoan coal, which reflected that the contents of partially hydrogenated hydroaromatics in oil fraction from the former were lower than those from the latter, and that the remarkable change of composition did not occur with the progress of the reaction. For both the coals, the remarkable changes in the average molecular weight of oil fraction were not observed with the progress of the reaction. While, the content of methane gradually increased with the progress of the reaction, which suggested that oil was gradually dealkylated. 5 figs.

  14. Survey on bio-chemical complex harmonized with global environment. 3; Kankyo chowagata seibutsu kagaku konbinato ni kansuru chosa. 3

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    A survey was conducted of bio-chemical complex harmonized with the global environment for the purpose of constructing the material production process harmonized with the environment by the process fusion between biological conversion and chemical reaction. Palm oil was taken up as renewable raw material plant resource. The process utilizing bio-chemical reaction advances at normal temperature and pressure and is high in reaction specificity and selectivity. This is a recycling, circulation and environmental harmony type production technology which brings high yield, energy conservation, resource conservation, and low environmental loads. Waste water treatment and production of useful substances from sludge were thought as elementary technology. A possibility was studied of enzyme production by culturing solid waste, and the enzyme was applied to the hydrolysis process. The paper indicated trace components in the palm oil and the extraction method and proposed the production process of new derivatives for adding value to hydrolysate. A study was also made of the overall process flow which integrated these new processes and the material balance. The comprehensive evaluation of this new process was made from the aspect of the product structure, the market, construction cost, economical efficiency, and the environment. 133 refs., 65 figs., 56 tabs.

  15. Estimation for origin of coals on biomaker analysis; Jinko sekitan oyobi tennen sekitan no biomaker bunseki ni yoru sekitan kigen busshitsu no suitei

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Y. [Geological Survey of Japan, Tsukuba (Japan); Sugimoto, Y. [National Institute of Materials and Chemical Research, Tsukuba (Japan); Okada, K. [Coal Mining Research Center, Tokyo (Japan)

    1996-10-28

    In order to study coal production processes, an estimation study was carried out on coal originating materials by using biomaker analysis. Test samples are original coals collected directly from a mine in Hokkaido (not having been subjected cleaning). Mixing and solvent extraction were performed after pulverization, and then tests were given on saturated hydrocarbon components divided by using a silicagel column chromatograph for the present study. It can be known from n-alkane distribution in the coal that low molecular alkane increases with increasing degree of coalification. Artificial coal made by wet-heating Metasequoia leaves contains only little n-alkane. Diterpenoid compound exists in the Taiheiyo and Akabira coals. Tetra-cyclic diterpernoid is contained abundantly in subtropical coniferous trees, serving as a parameter for warm environment. The compound is contained also in the Fushun coal, but not in Indonesian coals. Hopanoid constitution shows very high similarity, but H/C atomic ratio may vary largely even if the coalification is at the same degree. This is likely to be caused from difference in originating materials. Hopanoids are bacteria attributed substances, whose activities are not affected by the originating materials. 2 figs., 1 tab.

  16. Synthesis of materials under magnetic field and magnetic control of gas flow and combustion; Jibachu no busshitsu gosei oyobi jiba wo riyoshita kitairyu nensho seigyo

    Energy Technology Data Exchange (ETDEWEB)

    Wakayama, N. [National Institute of Materials and Chemical Research, Tsukuba (Japan)

    1997-12-20

    This paper presents recent research results on a magnetic field effect caused by another kind of magnetic force excluding an MHD effect. All of these researches have been conducted by using electromagnets or strong permanent magnets (Fe-Nd-B system). Even diamagnetic material which was considered to be poor in magnetic field effect because of its small magnetic force shows a large magnetic field effect at 0-1.5T. Some researches are as follows: transport of bubbles by magnetic buoyancy, virtual microgravity environment by magnetic force, and magnetic field orientation of protein crystals. Since recently a helium free superconducting magnet was developed, the environment in which not only experts but also anyone can easily use a strong magnetic field has been prepared. Use of a strong magnetic field for synthesis of functional materials is expected in the future. In addition, a permanent magnet requiring no energy source is effective for easy use of a strong magnetic field. 25 refs., 8 figs., 2 tabs.

  17. Overview of EPA`s proposal revision of the particulate matter standard; Beikoku kankyo hogocho ga teianshita ryushijo busshitsu kankyo kijun ni kansuru kaiteian no gaiyo

    Energy Technology Data Exchange (ETDEWEB)

    Maejima, K. [Japan Automobile Research Institute Inc., Tsukuba (Japan)

    1997-11-01

    U.S. Environmental Protection Agency in 1997 announced the new environmental standards covering the particulate matter (PM) smaller than 2.5{mu}m or less in diameter. As a document that explains how the standards came to be released, the original of the essay (made public in 1997) of R.O. McClellan and F.T. Miller is introduced. The themes discussed in the essay include: U.S. Clean Air Act and National Ambient Air Quality Standards; concept of PM; PM in the air (airborne PM): PM 10{mu}m or less in diameter and PM 2.5{mu}m or less in diameter; respiratory tract as PM`s target organ (respiratory system from nose and mouth to the remotest pulmonary alveolus); vital reaction (response of organism to PM); PM-related environmental standards, past and present; recent reviews concerning PM (various subjects that are attributed to exposure to PM, including: untimely death, changing for the worse of diseases relating to the respiratory system and cardio-vascular system, changes in pulmonary function, increase in the number of symptoms relating to the respiratory system, changes in pulmonary tissues and structures, changes in the defense mechanism of the respiratory system, etc.). 70 refs., 14 figs., 5 tabs.

  18. International symposium on environmental impacts of advanced alternative to CFC; CFC shinki daitai busshitsu no kankyo eikyo ni kansuru kokusai symposium hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-02-07

    The international symposium on environmental effects of new CFC substitutes was held in Tsukuba City, Ibaraki Pref. on February 7-9, 1996, and 19 papers were made public. In Session 1 (Plenary lecture), reports were made on Global warming and climate change: a review of recent studies; Stratospheric ozone, CFCs, and CFC-substitutes: an update, etc. In Session 2, Measurements of OH rate constants for advanced refrigerants as well as HCFCs and HFCs; The reaction rate of CFC alternatives with OH radical; Experimental and estimated rate constants: reactions of hydroxyl radicals with several halocarbons, etc. In Session 3, Measurement of uptake coefficients of some acetyl halides and fluorinated ethers into water; Mass transfer at the air/water interface: removal processes of halocarbonyl compounds; Heterogeneous reactions of fluorinated ethers on allophane or titanium dioxide, etc. In Session 4, papers were reported on model calculations relating to the global warming.

  19. Survey of pollution-resistant plants and their cultivating techniques; Osen busshitsu taisei shokubutsu to sono shokusai gijutsu ni kansuru chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The reduction of forests due to environmental pollution has been surveyed, to investigate the pollution-resistant plants and solid microorganisms. In Japan, the blight of needle-leaf trees (pine and momi fir) and of Japanese oak has occurred, and blight of some other trees, such as wild cherry trees, Japanese apricot trees, birch, Japanese cedar, cypress and bamboo, has been reported from various regions. In this article, plants reported to be resistant to pollutants are listed, and the physiological features of these plants are described. Furthermore, to develop pollution-resistant plants, reports relating to clarification of the mechanism of resistance development and the genes involved are reviewed. Microorganisms which symbioses for roots support these root functions. They also suppress the activity of pathogenic microorganisms and improve the environment around the roots, thus helping plants to grow normally. The roles played by symbiotic microorganisms and how to utilize these organisms are discussed. Their functions in coping with acid rain and heavy metal pollution, and how to utilize such functions are also discussed. 707 refs., 13 figs., 13 tabs.

  20. Proceedings of the papers of the 33rd Coal Science Conference (1996); Dai 33 kai sekitan kagaku kaigi happyo ronbunshu (1996)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-10-28

    This is a proceedings of the papers made public in the 33rd (fiscal 1996) Coal Science Conference held by the Japan Institute of Energy. The number of the papers included is 82. The processes such as coal liquefaction, coal gasification and pyrolysis are largely influenced by reaction of the carbon compound in coal. However, coal, which is different in reaction characteristics depending on its producing area, is a comprehensive compound. Therefore, the trial has been made for clarifying the molecular structure and skeleton. In the sense, the following papers are taken notice of: Suzuki and others` Estimation for origin of coals by biomaker analysis; Sugimoto and others` Change of unit skeletons during the artificial coalification; Hirado and others` Study on the correlation between chemical and mineral composition of coal ashes; Okawa and others` Coal structure construction system with construction knowledge and partial energy evaluation; Kanbayashi and others` Analysis of the relationship between coal properties and liquefaction characteristics by using the coal database.

  1. Expansion of colloid and surface chemistry to an interdisciplinary field. Biosimulation by liposome; Koroido kaimen kagaku wa gakusai ryoiki ni hirogaru. Liposome wo mochiite saibo kino ni semaru

    Energy Technology Data Exchange (ETDEWEB)

    Akiyoshi, K. [Kyoto University, Kyoto (Japan)

    1998-07-01

    This paper presents the usefulness of an approach using liposome as cell surface model system (biosimulation by liposome) for clarifying the cell control function of glycolipid. The author and others systematically studied the influence of the aggregation state of ganglioside glycochains on a liposome surface on adhesion and stimulus to cells. Study was also made on the interaction between DPPC liposome including ganglioside and immunocyte, in particular, T cell including an acceptor for glycochains. The interaction was evaluated by laser fluorescence microscope, and an increase in Ca concentration in cells was detected and evaluated by fluorescence probe. An activating rate was also evaluated by counting the number of stimulated cells among nearly 200 cells. As the study result on a degree of adsorption of liposome as fluorescence marker to cells, active systems were strongly adsorbed on cell surfaces, suggesting that signals are transmitted in cells after coupling of active systems with acceptors on cell surfaces. 10 refs., 5 figs.

  2. Investigations on an environment friendly chemical reaction process (eco-chemistry). 2; Kankyo ni yasashii kagaku hanno process (eko chemistry) ni kansuru chosa. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    In order to structure a chemical reaction process that does not discharge a large amount of waste by-products or harmful chemical substances, or so-called environment friendly process, investigations and discussions were given based on the results derived in the previous fiscal year. A proposal was made to reduce environmental load on development of oxidized and dehydrogenated catalysts that can produce selectively ethylene, propylene and isobutylene in an oxidation process. In liquid phase oxidation, redox-based oxidation and solid catalyzation of automatic oxidation reaction were enumerated. In acid base catalyst reaction, development of ultra strong solid acid was described to structure no pollution discharging process. In the fine chemical and pharmaceutical fields, the optical active substance method and the position-selective aromatics displacement reaction were evaluated to reduce environmental load. A questionnaire survey performed on major chemical corporations inside and outside the country revealed the following processes as the ones that can cause hidden environmental problems: processes discharging large amount of wastes, processes treating dangerous materials, and processes consuming large amount of energy. Development of catalysts is important that can realize high yield, high selectivity and reactions under mild conditions as a future environment harmonizing chemical process. 117 refs., 23 figs., 22 tabs.

  3. Trend of the strategy of European and American chemical industry in the restructuring; Obei kagaku sangyo no saihen ni miru senryaku no doko

    Energy Technology Data Exchange (ETDEWEB)

    Niimi, M.; Yamabe, T.

    1999-12-01

    The business of life science is the cover products which connect directly with life such as medical supplies, functional food, nutriments, agricultural chemicals or seeds. The wave of the reorganization of enterprises in the life science field also spread to the integration of the medicine specialty enterprises, and new association trees mainly on medical supplies such as Novartis in Switzerland, Zeneca, Astra Zeneca and Glaxo Wellcome in England were born. Many major chemistry manufacturers are also agricultural chemical manufacturers. Though agricultural chemicals were being shifted to one which being effective at the low use owing to the environmental problems, with the advance of the popularization of gene recombination crops, sales decreased on the agricultural chemical business more, and participation and restructuring to the seed business were accelerated. In this paper, the outline of business restructuring and strengthening the basic strategy in the main chemistry enterprises in Europe and the U.S.A. are described. As a trend of the restructuring, some examples on Du Pont, Dow chemical, Monsanto, ICI, Akzo Nobel, Novartis, Shell Chemicals, BASF, Hoechst and Bayer are introduced. (NEDO)

  4. Survey report on an environmental harmony type production system of chemical products; Kankyo chowagata kagaku seihin seizo system ni kansuru chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    As part of establishing an environmental harmony type production system of chemical products, study and survey were made on PET bottles. Using the life cycle analysis method (LCA), a study was made for proposing a material recycle (MR) method which is environmentally and economically excellent in the stage of recycling waste PET bottles. The total cost of recycling can be reduced by 34% supported by a decrease in equipment cost and improvement in yield if there is no mixture of foreign substances such as aluminum caps and PVC bottles. However, the ratio of the amount obtained from the reduction to the total production cost is small, and it is necessary to take measures from a viewpoint of the cost in a total production process and environmental loads. In a survey in Kawaguchi city, PET bottles discharged from the business sector occupied 41% of all the discharge amount. In a survey in Yokohama city, very important data were obtained on PET bottles appointed as the second type under the recycle law. The quality of PET bottles to be brought to the recycling plant is important for effectively processing PET bottles in MR method. For achievement of MR which is low in cost and small in environmental load, needed were cooperation by citizens, the shipping management system in autonomous government, and changes in design and material quality to be made by the industrial circle. 8 refs., 64 figs., 68 tabs.

  5. Report of the 8th International Symposium on the Observation of the Continental Crust Through Drilling; Dai 8 kai tairiku kagaku kussaku kokusai symposium ni sankashite

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, K. [Super Deep Core Drilling Study Group, Japan, Tokyo (Japan)

    1996-11-29

    This report relates to the 8th International Symposium on the Observation of the Continental Crust Through Drilling, convened at Agency of Industrial Science and Technology, Tsukuba City, on February 26, 1996. The symposium was represented by approximately 200 people from the U.S., Canada, Britain, Germany, France, Russia, China, and some others, who discussed active faults, drilling and logging, transfer of fluids and heat in the crust, history of the earth and climate, ICDP (International Continental Scientific Drilling Program) and international cooperation under this program in the future, etc. In reference to ultradeep drilling in the world, drillings by Germany`s KTB (Kontinentales Tiefbohrprogramm)(9,101m deep) and Russia at Kola Peninsula (l2,261m) were reviewed. Concerning the efforts of U.S. Continental Scientific Drilling Program during the previous 11-year period, it was reported that it had cost a total of $84,000,000; that investigations had been made into volcanos and geotherm, fault tectonics, sedimentary basins, holes due to meteorites, and metal ore deposits; and that 61 holes (total length: 31,310m and maximum depth: 3,510m) had been drilled and investigated. 6 figs., 3 tabs.

  6. Production of activated carbon from acrylonitrile and methyl acrylate copolymers. Akurironitoriru/akuriru san mechiru kyojugotai wo mochiita kagaku shoriho ni yoru tansokei kyuchakuzai no seizoho

    Energy Technology Data Exchange (ETDEWEB)

    Noda, Y.; Yamada, K.; Ishibashi, K. (Government Industrial Development Lab. Hokkaido, Sapporo (Japan)); Kumamoto, S.; Takahashi, Y. (Environmental Research Inst. of Sanyu Plant Co. Ltd., Kanagawa (Japan)); Kobashi, T.; Takagi, J. (Japan Exlan Co. Ltd., Okayama (Japan))

    1993-06-20

    Carbonization of carbonaceous adsorbents, in which acrylonitrile (AN) and methyl acrylate copolymers(PANA) are used as raw materials, in order to discover high functionability, manufacture condition of the activated coal by chemical activation method using phosphate and zinc chloride as an activation promoters, and the performance of each formed products, are reported. The maximum value of methylene blue absorption quantity(MB) and the inner surface area(S) was shown by both the samples within the activation temperature range of 600[degree]C to 900[degree]C. The values of MB and S has increased linearly with the increase of activation temperature for both PANACHZ and PANACHP which are obtained by adding ZnCl2 and H3PO4 respectively in thermal condensation product(PANACH). Adsorbability of PANACHZ and PANACHP increased with the increase of activation temperature. The amounts of adsorption by activation products and organic gases of PANACHZ and PANACHP were pursued. As a result, it was revealed that the amounts of adsorption for both chars increased with the increase of activation temperature. Furthermore, adsorption quantity of butyl mercaptan gas was more than twice of comparative activated carbon on the market, and highly efficient adsorbent was obtained. 19 refs., 11 figs., 2 tabs.

  7. Food and chemical industry. Concentration and drying in the manufacture of instant coffee; Shokuhinn to kagaku kogaku. Insutanto coffee no seizo ni okeru noshuku to kanso

    Energy Technology Data Exchange (ETDEWEB)

    Imura, N. [Tokyo Univ. (Japan)

    1997-05-05

    In this paper, the history and manufacturing method of instant coffee are introduced emphasizing the concentration and drying technology in the manufacturing process of instant coffee. Instant coffee can be roughly classified into three kinds as those respectively made from freeze drying, spray drying and the agglomeration after drying, which are different in shapes and properties from each other. For obtaining quality instant coffee remaining more aroma of coffee extract, it is extremely effective and important to increase the concentration of solid component of coffee in extract simultaneously with the setting of conditions of drying process. Thermal concentration, freeze concentration and membrane concentration are used in the concentration of coffee. Spray drying and freeze drying are executed to remove water from concentrated coffee liquid as the finishing step of the manufacture of instant coffee. 3 refs., 4 figs.

  8. Coliquefaction of coal, tar sand bitumen and plastic (interaction among coal, bitumen and plastic); Sekitan/tar sand bitumen/plastic no kyoekika ni okeru kyozon busshitsu no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, H.; Okuyama, Y.; Matsubara, K. [NKK Corp., Tokyo (Japan); Kamo, T.; Sato, Y. [National Institute for Resources and Environment, Tsukuba (Japan)

    1996-10-28

    For the improvement of economy, coliquefaction of coal, tar sand bitumen and plastic was performed under low hydrogen pressure, to investigate the influence of interaction among these on the liquefaction characteristics. For comparison, coliquefaction was also performed under the hydrogen pressure same as the NEDOL process. In addition, for clarifying its reaction mechanism, coliquefaction of dibenzyl and plastic was performed as a model experiment, to illustrate the distribution of products and composition of oil, and to discuss the interaction between dibenzyl and various plastics, and between various plastics. Under direct coal liquefaction conditions, coprocessing of Tanito Harum coal, Athabasca tar sand and plastic was carried out under low hydrogen pressure with an autoclave. The observed value of oil yield was higher than the calculated value based on the values from separate liquefaction of coal and plastic, which suggested the interaction between coal and the mixed plastic. The results of coliquefaction of coal, tar sand bitumen and plastic could be explained from the obtained oil yield and its composition by the coliquefaction of dibenzyl and plastic. 2 refs., 3 tabs.

  9. Report on the FY 1999 research survey on the industrial utilization/development of the biofilm formation mechanism and antifouling substances; 1999 nendo bio film keisei kiko oyobi sogai busshitsu no sangyoteki riyo kaihatsu chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The paper described the results of the FY 1999 research on the fouling by marine aufwuchs. The survey is aimed at searching the nature world for active substances for biological antifouling. The fouling mechanism in the ocean is as follows. The adsorption of organisms called the conditioning film first occurs on the surface, and next, bacteria and diatom around the surface form biofilm and cover. After that, biological fouling by large aufwuchs occurs. Therefore, the control of biofilm formation was regarded as most important, and with this as a guidepost, the search was conducted. Using biofilm anti-formation activity and periphytic bacteria anti-growth activity as guideposts, some compounds were searched for. Being aimed at Porifera, in particular, new compounds were isolated from it. Since few of other organisms attaches on the surface of sponge, there is a great possibility of Porifera's producing any anti-fouling substances. Further, it is thought that symbiotic microorganisms of sponge (40% of the total weight) produce various biologically active substances. Synthetic phenethyl amine derivatives were also studied. (NEDO)

  10. Fiscal 1998 research report. Study on the feasibility of microorganism biotechnology for effective use of environmental pollutants. Pt. 2; 1998 nendochosa hokokusho. Kankyo osen busshitsu no shigenka no tame no biseibutsu bio technology riyo kanosei ni kansuru chosa. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Study was made on the feasibility of microorganism biotechnology for effective use of environmental pollutants and unused resources. Microorganisms and microorganism enzymes for decomposing lignocellulose were viewed, and uses of hydrolysis products were summarized. Production of microorganisms applicable to fodder, composting, and production of energy sources (methane, hydrogen, ethanol) were studied. Use of vegetable fiber residues such as beer lees as fungus cultivation medium and conversion to valuable substances were also studied. Microorganisms treatment (MT) of wastes in fats and oils industry was summarized. Effective use of MT of protein waste from marine products was studied. MT of manures with the greatest impact on environment as livestock waste was summarized. The necessity of separate collection of domestic wastes, and composting and methane fermentation of kitchen garbage were reported. The feasibility of MT of plastic wastes, and decomposition of halogenated methane with high toxicity were also studied. (NEDO)

  11. Survey report of FY 1997 on the feasibility of microbial biotechnology for reuse of environmental pollutants; 1997 nendo chosa hokokusho (kankyo osen busshitsu no shigenka no tame no biseibutsu bio technology no riyo kanosei chi kansuru chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    An investigation was conducted with the aim of elucidating the foundations for effective utilization of environmental pollutants or unused resources which are likely to be causal substances of environmental pollutants, as resources, using biotechnology. Composting of agricultural waste, production of microbial mycelium proteins and microbial fermentation materials were suggested as main examples of effective utilization of unused resources by microorganisms. Selection of active microorganisms in the livestock waste, clarification of the mechanism of action and the establishment of treatment conditions are essential to new developments in this field. In the field of marine products industry, it was pointed out that the recycling of waste using microorganisms and enzyme treatment is the most promising approach to the effective utilization of resources. In the field of food industry, applications as the culture media for mushrooms, for enzyme production and for the production of physiologically active materials as well as fuel were clarified. Was also pointed out the significance of studies on the microorganisms and enzymes in resources containing cellulose, hemicellulose and lignin, and the waste from these resources, lignocellulose. Were also proposed the composting of household waste, methane fermentation, and fermentative production of organic acid and hydrogen from waste. Possibility and significance of fermentative production of organic acid from sewage sludge were suggested. 314 refs., 46 figs., 33 tabs.

  12. Synthesis of (E)-9-Oxo-2-decenoic acid (the queen substance of honeybee) from methyl 3-formylpropionate; 3-horumiruporopion san mechiru wo mochiita (E)-9-okiso-2-desen san (Mitsubachi joo busshitsu) no gosei

    Energy Technology Data Exchange (ETDEWEB)

    Tsukasa, H. [Toyotama Koryo Co. Ltd., Tokyo (Japan)

    1997-05-20

    The queen substance, (E)-9-oxo-2-decenoic acid (1) is a pheromone secreted by queen honeybee (Apis mellifera) and inhibits reproductive ability of worker bees. Several synthesese have been reported. It was synthesized starting from methyl-3-formylpropionate this time. Methyl 7,7-ethylenedioxy-4-oxooctanoate was prepared by radical addition reaction from (2) and 2-methyl-2-vinyl-1,3-dioxolane and reduced to an ethyelenedioxy carboxylic acid with hydrazine and KOH. This compound was converted to an alcohol by reduction with sodium bis(2-methoxyethoxy)aluminum hydride, followed by oxidation with pyridinium chlorochromate to an acetal aldehyde, which was condensed with malonic acid and (1) was obtained after the hydrolysis with hydrochloric acid. 7 refs., 1 tab.

  13. Bioremediation of recalcitrant chemical pollutant-contaminated soil. Applying edible mushroom cultivation waste to bioremediation; Kinoko kinsho ni yoru nanbunkaisei busshitsu osendo no bioremidiation. Kinoko kinsho no rigunin bunkai koso kassei to takan hokozoku tanka suiso no bunkaino

    Energy Technology Data Exchange (ETDEWEB)

    Okada, S.; Oide, E.; Oshima, Y.; Tsuji, H. [Obayashi Corp., Tokyo (Japan)

    2000-01-10

    Bioremediation is a viable and cost effective method for soil contaminated with a variety of chemical pollutants. White-rot fungi, with emitted extracellular free radicals, are known to be able to decompose lignin, which is usually nonbiodegradable by most bacteria. The decomposition mechanism has been shown to be attributed, at least in part, to lignolytic peroxidases. We examined a method that utilizes edible mushroom cultivation waste as the microbial source, and found that these waste materials have high lignolytic peroxidase activity and degradated polyaromatic hydrocarbons in sands. (author)

  14. Development of stereoselective analytical methods of chiral drugs and biological substances and application of hepatic local drug disposition; Yakubutsu oyobi biryo seiri kassei busshitsu no rittai sentakuteki bunri bunsekiho no kaihatsu to kanzo kyokusho dotai kaiseki eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Nakagawa, T. [Kyoto University, Kyoto (Japan). Faculty of Engineering

    1994-12-15

    With an objective to elucidate the structure recognizing ability possessed by living organisms, discussions were given on methods to analyze the bonds between optically active drugs and polymers, and methods to analyze drug disposition fluid-dynamically. Studies have been advanced on the following themes, and the results were obtained therefrom: development of an on-line system to quantify non-protein bonding type concentrations in drugs utilizing the high-performance fraction analysis (HPFA, using a restricted movement type HPLC column) that had been already developed, establishment of a method to analyze hepatic local drug disposition by using the MULTI (drug disposition analyzing) program, and studies on stereoselectivity by using NMR generated by interactions of local anesthetics and lipids. The following findings were obtained: using the above on-line system, a discussion was given on protein bonds between BOF-4272 (xanthine oxidase inhibitor) and serum albumins, and the discussion was found effective in analyzing the stereoselectivity in drugs with strong protein bond; and with the above analytic method, optical behavior of ketoprofen (KP) in rat liver perfusion was discussed, wherein the transfer of KP into liver tissues was estimated to have been caused by involvement of active transportation rather than physical diffusion. 7 refs., 6 figs., 4 tabs.

  15. Concurrently inhibitory and allelopathic effects of allelochemicals secreted by Myriophyllum spicatum on growth of blue-green algae; Hozakinofusamo ga hoshutsushita areropashi busshitsu no aisorui ni taisuru fukugo sayo oyobi areropashi koka no hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Nakai, S.; Inoue, Y.; Hosomi, M.; Murakami, A. [Tokyo Univ. of Agriculture and Technology, Tokyo (Japan)

    1998-10-10

    This paper describes effects of allelochemicals secreted by Myriophyllum spicatum on growth of blue-green algae. In order to propose an effective growth inhibitory method of blue-green algae with less impact on the ecosystem, biological interaction (allelopathy) between large aquatic plants and algae was investigated. Pyrogallic acid, gallic acid, catechin and ellagic acid secreted by M. spicatum provided growth inhibitory effects of blue-green algae (Microcyctis aeruginosa), individually. Complex interaction and allelopathic contribution of these four polyphenols were evaluated. By comparing the actual effects with the expected values, synergetic growth inhibitory effects were recognized by adding four polyphenols at the same time. Furthermore, growth inhibitory effects were evaluated for actual culture solution of M. spicatum and simulated culture solution made by four polyphenols. As a result, it was found that these four polyphenols relate to allelopathy of M. spicatum. 25 refs., 6 figs., 4 tabs.

  16. Application of resin lining system for countermeasures for preventing leakage from openings in low temperature materials storage; Teion busshitsu chozoji no ekimore oyobi reiki more taisaku toshite no kobunshikei zairyo no tekiyosei

    Energy Technology Data Exchange (ETDEWEB)

    Inada, Y. [Ehime Univ., Ehime (Japan). Faculty of Engineering; Seki, S.

    1996-12-21

    Recently, many of the low temperature materials such as LNG and LPG used as an energy substitution for petroleum were stored in the reclaimed land of the sea side district, however, it is necessary for those storage methods to enlarge sites. Therefore, it was considered to directly store the low temperature materials in openings excavated in the rock mountains. However, countermeasures for leakage of liquid and cold gas from cracks in openings would be an important subject. In this study, as a countermeasure for leakage of liquid and cold gas in the case in which low temperature materials were stored in openings in the rock mountains, the lining of resin materials on the surface of openings was proposed. Characteristics of strength and deformation and values of the thermal physical properties for the resin materials at the low temperature were obtained by experiments. This material was compared with granite supposed as a parent rock, and the thermal property of the resin materials was understood. Next, an analysis was conducted in the case of using the resin materials as a lining, the behavior of the surrounding rocks of the openings and the stability of the lining were investigated. 17 refs., 25 figs., 2 tabs.

  17. Characteristics of the fluorescent substances in the Yodo River system by three-dimensional excitation emission matrix spectroscopy; Sanjigen reiki/keiko kodoho ni yoru yodogawa suikeichu no keiko busshitsu no tokucho

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, Y.; Nakaguchi, Y.; Hiraki, K.; Kudo, M.; Kimura, M.; Nagao, S. [Japan Atomic Energy Research Inst., Tokyo (Japan)

    1998-08-01

    Organic substances in the river water in Yodo River system were analyzed by three-dimensional excitation emission matrix spectroscopy. Fluorescent substances were taken as an index of organic substances. The amount of fluorescent substances varied widely depending on the environment of river basin. It is suggested that the fluorescent substances are composed of organic substances which is not directly originated from biological activity. It is suggested that the fluorescent substances were produced by leaching of river bottom sediment. The fluorescent substances in Yodo River system consists of fulvic acid-like substances and protein. The analysis of fluorescent substances in river water by three-dimensional excitation emission matrix spectroscopy can be useful means for estimation of variation and origin of fluorescent substances. For better understanding of features of fluorescent substances in the surface water into which various kinds of substances enter, it is necessary to determine the exact sampling points based on the consideration of different sources and to make a database of peak positions for identification of fluorescent substances from fluorescence intensity peak. 29 refs., 3 figs., 2 tabs.

  18. Proceedings of the Joint Meeting of The Fuel Society of Japan (1991). 28th Coal Science Conference/91st Coke Meeting; (Sha) nenryo kyokai godo taikai happyo ronbunshu (1991). Dai 28 kai sekitan kagaku kaigi dai 91 kai cokes tokubetsukai

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-07

    Relating to coke, studies are made on the rapid coke production method, oven investigation during carbonization, and operational management/control. As to coal science, studies are mainly on the brown coal two-stage liquefaction (BCL) method, and data on the pilot plant and PSU are reported. Concerning bituminous coal liquefaction, PSU data mostly including the NEDOL process, and characteristics of liquefaction residue and its effective utilization by thermal decomposition are reported. Regarding the liquefaction mechanism, an experimentally extensive study on catalyst, solvent and reaction conditions is made using model materials and coal itself on the bench scale and also in the pilot plant. Engineering subjects on residue, solvent deashing, scale attachment and coprocessing are also reported. Relations of decomposition process to coal chemical structure changes and reaction conditions are investigated. As to coal gasification, studies, which are not many, are conducted on material balance, heat balance, and image characteristics of char for gasification and factors controlling reactivity.

  19. Research on energy conservation in petrochemical and steelmaking industries in a developing country (India); Hatten tojokoku (Indo) ni okeru sekiyu kagaku kogyo tekkogyo no energy shohi koritsuka ni kansuru chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Current state of energy conservation in petrochemical and steelmaking industries in India was surveyed to estimate energy consumption and demand, and discuss possible international cooperation. Recently India has grown rapidly, and its growth rate of energy consumption is higher than a rise in GDP. In order to examine the current state of energy conservation in India, major energy consumption levels in India was surveyed together with production outputs of steelmaking, oil refining and petrochemical industries. Energy consumption and the potential of current energy-saving programs were also surveyed in modern factories. As a result, for energy conservation in petrochemical and steelmaking industries in India, the following were pointed out: improvement of operation conditions in current facilities, improvement of management systems in current facilities such as introduction of computers, and modification of production processes. Improvement of energy efficiency by introducing advanced technologies from developed countries such as Japan was essential. 37 figs., 45 tabs.

  20. Overview of FY1997 human media technology R and D; 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu seido Shin energy Sangyo Gijutsu sogo Kaihatsu Kiko itaku jigyo. Human media no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper reports a summary of results in fiscal 1997 of research and development of human media technology. Fiscal 1997 launched design and trial fabrication of the following items: interface to improve efficiency and safety of plant operators, accommodation of multimedia contents to aid Kansei design, city development design aiding technologies using contents retrieval and presentation technologies and virtual reality, and empirical evaluation technologies for safety, comfort and convenience. Specific study assignments were extracted on a virtual media technology, a Kansei media technology and a knowledge media technology being three elementary technologies for human media to make clear the research and development approaches to be taken in the coming fiscal years. In addition, a human media technology committee, a research and development working group, and an investigation working group were established. Also launched were investigations on research trends in the human media technology, and investigative researches on contacts of information needs in industries with human media. 59 refs., 114 figs., 24 tabs.

  1. Chitosan hydrolysis using chitosan decomposition enzyme chemically modified by polyalkylene oxide - maleic anhydride copolymers; Poriarukirenoshido, musui marein kankyojugotai ni yotte kagaku shushoku shita kitosan bunkai koso wo mochiita kitosan kasui bunkai

    Energy Technology Data Exchange (ETDEWEB)

    Araya, Yoshitsune; Kajiuchi, Toshio; Hinode, Hirofumi; Haku, Tatsuto

    1999-01-05

    Pectinase on the market, which has chitosan hydrolysis activation, was chemically modified using two polyalkylene oxides - maleic anhydride copolymers of different hydrophilicity; the effect of the chemical modification of enzymes on the chitosan hydrolysis characteristics was experimentally investigated. As the characteristics, the initial activation of enzymes, the dynamics constant based on the Michaelis-Menten mechanism, thermal stability, and the variation of generating, reduced sugar quantities with time by the hydrolysis reaction were investigated. The result clarified that the hydrophilicity of modifiers and the modification rate of enzymes affected greatly the above enzymes characteristics. The initial activation of highly chemically modified enzymes was low regardless of the hydrophilicity of modifiers. It was confirmed that the Michaelis-Menten constant decreased, i.e. the affinity of modified enzymes and substrate increased, and that the thermal stability rose at 40 degrees C. It was also known that the chitosan hydrolysis reaction continued for a longer time when the modified enzyme was used. The above enzyme characteristics improved greatly when the modification rate raised using the hydrophilic modifier AKM-1510, polyalkylene oxide chain of which consists of only ethylene oxide. (translated by NEDO)

  2. FY 2000 Industrial science and technology research and development themes - cooperative project with academic circles. Report on the results of research and development for creating new bioaffinity molecules using submicron beads (Research and development for creating new bioaffinity molecules using submicron beads); 2000 nendo biryushi riyogata seitai ketsugo busshitsu nado sosei gijutsu no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Described herein are the FY 2000 results of the research and development of technologies for creating new bioaffinity molecules using submicron beads, including those for organic receptor analysis and refining. The program for development and research of fixation technology develops immobilizing reaction and latex particle having cleavable linker, and synthesize small molecules for the identification of target receptors. The program for development of organic receptor refining technology directly refines cisplatin-telomere binding proteins from crude nuclear extracts of HeLa, and analyzes them; analyzes the functions of Ref-1 purified from Jurkat cell nuclear extracts as the binding protein for drug E3330 which specifically controls the transcriptive factor NF-{kappa}B; and studies LK6A having an MLR inhibiting activity, promoters for production of Alendronate, Taxol and leptin, D91-6092 as a promising anti-cancer agent, and antirheumatic, antiallergic, antitumor agents and FK506 as immunosuppressant agent. (NEDO)

  3. FY 1998 results of the intellectual basement project using functions of private companies (venture promotion type basement creation R and D project). Development of endocrine disrupter testing method and development of environmental assessment method; 1998 nendo naibunpi kakuran busshitsu ni taisuru shiken hoho kaihatsu oyobi eikyo hyoka shuho kaihatsu hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of assessing the risk in relation to endocrine disrupting chemicals, the following were conducted: development of testing/assessment method for endocrine disrupting chemicals, survey of the actual exposure assessment, development of measuring method for the concentration in the environment. In the development of the testing method, the following were carried out: development of a high-throughput screening method for evaluating endocrine disrupting chemicals; as screening testing method using mammals, uterotrophic assay, Hershberger assay using castrated male rats, thyroid hormone assay in pubertal rats, enhanced OECD 407 test guideline for 28-day toxicity test; study on yeast two-hybrid assay for endocrine disrupter; sex-reversal assay for suspected endocrine disrupting chemicals using S-rR strain medaka. In the development of exposure assessment method, estrogenic potency of individual nonylphenol congeners isolated from technical mixtures; determination of endocrine disrupters and related chemicals from industry and nature origin in river water and sediment; research for the flow of industrial origin chemicals; reconstruction of pollution history of chemicals using sediment cores. (NEDO)

  4. Fiscal 1998 achievement report on regional consortium research and development project. Regional consortium of venture business fostering type--Creation of key industries (Development of technologies for manufacturing and utilizing various biological regulatory substances using Hokkaido-produced biomasses as materials); 1998 nendo Dosan biomass wo genryo to shita kakushu seitai chosetsu kino busshitsu no seisan riyo gijutsu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The efforts aim to meet consumers' needs for products that will prevent lifestyle diseases or the like. For this purpose, substances answering the purpose are extracted from Hokkaido-produced agricultural and aquatic biomasses, and prepared for testing. Researches are conducted on how they behave in the enzyme, cell, and biological systems, and active substances are isolated and identified. In relation to the aquatic biomass, a technology is established of extracting and separating DHA (docosahexaenoic acid), EPA (eicosapentaenoic acid), taurine, etc., which are multivalent unsaturated fatty acids effective in preventing lifestyle diseases, from the unused parts of the squid. In relation to the agricultural biomass, antimicrobial active substances are extracted and separated from small fruit plants such as the chicory. Long-keeping foods are tentatively produced by the addition of dried powder of the chicory root tuber. In the elucidation of various biological regulatory substances contained in the Hokkaido-produced biomasses, they are tested for their abilities to resist microbes and active oxygen. Furthermore, verification tests are conducted by administering the substances to the senescence-accelerated mouse (SAM). (NEDO)

  5. International seminar in fiscal 1998 on the development and promotion of global environment-related industrial technologies. Report on International Workshops on CO{sub 2} Cycling and Metabolism in Coral Reef; 1998 nendo chikyu sangyo gijutsu kaihatsu suishin jigyo. 'Sangosho ni okeru busshitsu ido to tanso junkan' kokusai workshop hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    For the study of CO{sub 2} absorption and fixation in the marine ecosystem, studies of coral reefs by RITE (Research Institute of Innovative Technology for the Earth) were subjected to discussion at the above-named workshops. It is after the elapse of a long geological time on the earth that CO2 in the atmosphere has arrived at the current level of concentration thanks to fixation and calcification by living organisms and to dissolution into the seawater. In the formation of CaCO{sub 3} that constitutes the coral skeleton, 1 mol Ca combines with 2 mol bicarbonates for the production of 1 mol CaCO{sub 3} and 1 mol CO{sub 2}. The reaction may suggests a consequential increase of CO2 in the atmosphere but such CO{sub 2} is in reality consumed by being converted into organic substances in a photosynthetic process performed by symbiotic algae. Calculation was made for the whole of Bora Bay, Miyakojima Island, and the result was that 700kg-C/day comes to be stored in the form of organic matters in the community of coral reef organisms. In a coral reef, even when it emits CO2 into the atmosphere, there is organic matter production which exceeds the lost CO{sub 2}. Coral reefs fix carbon out of the seawater at the rate of 0.42Gt-C/year, which is the aggregate of 0.3Gt organic matters and 0.12Gt CaCO{sub 3}. (NEDO)

  6. FY 2000 report on the R and D of the particulate utilization type creation technology of biological connective substances. Survey of the technical trend overseas; 2000 nendo biryushi riyogata seitai ketsugo busshitsu nado sosei gijutsu no kenkyu kaihatsu seika hokokusho. Kaigai gijutsu doko chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The paper summarized the reports on the results of Japanese engineers' participating in the related scientific meetings held overseas as a survey report on the trend of the overseas technology. The scientific meetings they participated in were: 1) Impact of Genomics on Medicine and Pharmacogenomics Europe (Amsterdam; May 15-26, 2000), 2) Drug Discovery Technology 2000 (Boston; August 10-20, 2000), 3) Biotechnology 2000 (Berlin; September 3-12, 2000), 4) PacificChem 2000 (Hawaii; December 14-21, 2000), 5) 4th Winter Conference on Medicinal and Bioorganic Chemistry (Seattle; January 27 - February 4, 2001). Impact of Genomics on Medicine was composed of the following five fields: microarrays, proteomics, functional genomics and target validation, genetic variation technology, and applications of SNP analysis (joint session). Pharmacogenomics Europe was composed of the following four fields: applications of SNP analysis (joint session), SNP assays, targets and compounds, and clinical applications. (NEDO)

  7. FY 2000 report on the results of the regional consortium R and D project. First year report. Regional new technology creation R and D. Development of the technology to produce useful substances by biosynthesis engineering; 2000 nendo chiiki consortium kenkyu kaihatsu jigyo - chiiki shingijutsu soshutsu kenkyu kaihatsu. Seigosei kogaku ni yoru yuyo busshitsu seisan gijutsu no kaihatsu (shonendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    On the basis of the basement technology such as the cloning technology of biosynthesis enzyme gene groups of secondary metabolite of plant and the identification technology of the expression protein enzyme function in the heterologous expression system, the development was proceeded with of the technology to produce useful substances using the biosynthesis function of plant components. Studies were made in the following four fields: 1) cloning of genes of useful biosynthetic plants and functional elucidation/application of the related genes; 2) analytical technology of genes and proteome; 3) development of plant genome database; 4) comprehensive investigational study. In FY 2000, in 1), the cloning was conducted of biosynthetic enzyme genes of oxidation resistant polyphenol, bioactive triterpenoid saponin, etc., and the function of a part of the enzyme proteins was elucidated. In 2), as the basic technology for improving producibility of secondary electrophoresis, fabricated was the electrophoresis chip so structured that slide glasses on which micro-channels were two-dimensionally fabricated were joined. (NEDO)

  8. Fiscal 1996 report on the results of the R and D under a consignment from NEDO of the environment friendly type production technology. High-functional chemical synthesis bioreactor (for public); 1996 nendo chikyu kankyo sangyo gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Kankyo chowagata seisan gijutsu (kokino kagaku gosei bioreactor) kenkyu kaihatsu seika hokokusho (kokaiyo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    For the purpose of developing production technology of chemical substances which are resource conservative, energy saving and less in environmental loads, a R and D was conducted of a high-functional chemical synthesis bioreactor. The paper reported the results of fiscal 1996. As for proliferation control breeding technology, relating to the switch control technology of proliferation related genes by regulatory factors, the effectiveness on an incubator level was demonstrated, and at the same time improvement of reactor performance in using this technology was studied on paper. As to the manifestation control breeding technology, the actual design of the development of manifestation promotion technology by bent DNA, etc. was proceeded with, and at the same time the following were commenced: selection of bent DNA, confirmation of bent characteristics, and work of vector construction using candidate bent DNA. Further, the simple assessment system of manifestation vectors was constructed. In the development of bioreactor system technology, the actual design was started of the two-stage culture continuance system which separated proliferation and enzyme production. 48 refs., 41 figs., 6 tabs.

  9. Fiscal 1997 R and D project on industrial science and technology under a consignment from NEDO. R and D of the ultimate manipulation technology of atoms and molecules; 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo gijutsu Sogo Kaihatsu Kiko itaku. Genshi bunshi kyokugen sosa gijutsu no kenkyu kaihatsu seika hokokusho (genshi bunshi kyokugen sosa gijutsu no kenkyu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper describes R and D of the ultimate manipulation technology of atoms and molecules (atom technology). The R and D aims at establishment of observation/manipulation technology of atoms and molecules as common basic technology in various industrial fields such as new material, electronics, bio-technology and chemistry. The R and D thus aims at establishment of observation/manipulation of solid surfaces and DNA organic molecules, formation of fine structures of atomic surface arrangement, and calculation/ simulation for predicting a reaction theorem of atom and molecule surfaces. In fiscal 1997, research was made on improvement and development of computer simulation environment, and description of an excited state of electrons by Green function. Establishment of a construction method and computation code is under investigation for pseudo- potential dependent on excitation energy. Survey was made on research trends of the atom technology by visiting overseas academic societies and institutions. International Symposium on Atom Technology was also held in Tokyo in Nov. 1997

  10. Fiscal 1998 R and D project on global environmental industrial technology. R and D result report on environment- friendly production technology (advanced chemical synthesis reactor); 1998 nendo chikyu kankyo sangyo gijutsu kenkyu kaihatsu jigyo. Kankyo chowagata seisan gijutsu (kokino kagaku gosei bio reactor) kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    For high-efficiency production of substances by bioreactor, study was made on a bio-control mechanism as its elementary technology. On the study of breeding technology by expression control, the structure design of a control region and development of new expression vectors had been finished, and study was made on breeding of high-efficiency recombinant production cells by using candidate expression vectors. On the study of breeding technology by multi-stage enzyme reaction control, the enzyme gene of a system synthesizing cysteine from glycerol was searched, and hydroxypyruvaldehyde hydrogenase gene was isolated as substance production model. Cysteine production Escherichia coli combined with serineacetyl transferase gene was also prepared. In addition, study started on cloning of hydroxyacetone oxidase gene. On development of reactor system technology, for conversion of serine to cysteine, study was made on optimization of a reaction condition by theory of enzyme reaction rate. (NEDO)

  11. Industrial science and technology research and development business for fiscal 1998. Research and development achievement report on glycoconjugate production and utilization technologies (Development of technologies of glycoconjugate-aided CO{sub 2} fixation and utilization); 1998 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo. Fukugo toshitsu seisan riyo gijutsu no kenkyu kaihatsu seika hokokusho (fukugo toshitsu oyo nisanka tanso koteika yuko riyo gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Enzymatic and chemical methods were combined and methods were developed for synthesizing mucin type sugar chains and glycopeptides. The influence of sugar chain positions and structures on glycoconjugate stereo structures and physiological activities was analyzed, and glycopeptide structural activities and glycoconjugate remodelling were studied. To create an industrial advantage in a glycoprotein production system by use of zooblasts, sugar chain structure control through sugar transfase occurrence control was studied. For the production of man-adaptive sugar chains using yeast, new yeast variations were subjected to molecular breeding, and tested for the resultant improvement on productivity. Sugar chain marking and refining techniques and various responding mechanisms on the solid surface were elucidated, which enabled structure analyses using sugar chain recognition molecules such as lectins and antibodies. A database on interactions between sugar chains and sugar chain recognition molecules was constructed using the said findings. An analyzing program was also formulated tentatively. This paper also covers general surveys and studies on technologies of producing and utilizing glycoconjugates. (NEDO)

  12. Fiscal 1997 report on the results on the international standardization R and D. Development of chemical methods to analyze/evaluate metallic coatings of surface treated steel coating sheets; 1997 nendo seika hokokusho kokusai hyojun soseigata kenkyu kaihatsu. Hyomen shori koban mekkiso no kagaku bunseki hyoka hoho no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper studied the international standardization of the chemical analysis method and glow discharge optical emission spectrometry. Chemical composition and coating thickness (g/m{sup 2}) of 14 kinds of specimens including alloy coatings and organic coating with zinc and aluminum as base were analyzed by the above-mentioned methods to examine the relation between the both. As the chemical analysis method, used was inductively coupled plasma atomic emission spectrometry. To study the relation between the methods, it was found to be necessary to recognize morphology at the boundary between the coating and base steel using, for example, scanning electron microscope (SEM) and electro-probe micro-analysis (EPMA). To measure traceability of the analysis method, with the chemical analysis method as a judgement method, it is necessary to make reference materials by coating materials, to use the calibration graph confirmed by the materials and to adopt the glow discharge optical emission spectrometry. On the basis of such way of thinking, drafts were worked out for the international standardization of the chemical analysis method and glow discharge optical emission spectrometry. 7 refs., 117 figs., 33 tabs.

  13. Fiscal 1997 report of the R and D result of industrial science and technology. R and D on synergy ceramics (R and D on an ultrahigh-temperature gas turbine for power generation); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu seika hokokusho. Synergy ceramics no kenkyu kaihatsu (hatsuden`yo chokoon gas turbine no kenkyu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    For development of high-efficiency power generation gas turbines using petroleum substituting energy, the process technology which can highly harmonize conflicting characteristics and various functions was developed for new ceramic materials. This paper summarizes the result in fiscal 1997. On design technology of the characteristics harmonizing process, the design and synthesis of ceramic precursors were made by using chemical reaction of metal organics. On analysis of fracture behavior by controlling microscopic and macroscopic particle shapes, orientations were observed by convergent ion beam. On control technology of a structure formation process, study was made on continuous pore shape control to form porous material with uni-directionally arranged pores in ceramic matrix, interface control between particles to decrease a plastic deformation temperature and improve a heat insulation, interface control between phases of a rare-earth silicate/silicon-carbide-based composite, boundary control between layers of piezoelectric ceramics, and boundary control of the composite where inorganic-organic hybrids occupy the interface between ceramic particles. 79 refs., 193 figs., 15 tabs.

  14. Fiscal 1996 project on the R and D of industrial scientific technology under consignment from NEDO. Report on the results of the R and D of technologies to invent original high-functional materials; 1996 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Kaihatsu Kiko itaku. Dokusoteki kokino zairyo sosei gijutsu no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Technologies were described of creating original high-functional materials. The paper presented the following two as fields of technology on which importance is to be placed for the future R and D from technological and socioeconomic points of view. In the field of new materials of living organism imitation type, remarkably high-performance/high-functional new materials are invented by imitating the precise function manifestation mechanism of the ultimate living organism in which a great variety of matters are in harmony with each other and manifest complicated and high-level functions. In the field of structural control/synthesis process technology, the paper is aimed at manifestation of newer and higher functions/performance and innovation of the synthesis process, and also at developing technology to precisely control structure and process of materials including surface and interface in correspondence with atomic/molecular to macro levels. Up to the present, conducted were an examination of autonomous response materials (the subtheme is a R and D of polymer/composite multi-stimuli-responsive materials) and a R and D of precise polymerization (control) polymer materials. 239 refs., 129 figs., 49 tabs.

  15. FY 1996 R/D project of industrial and scientific technologies contracted with NEDO. Report on R/D of organosilicon polymers; 1996 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Keisokei kobunshi zairyo no kenkyu kaihatsu (Keisokei kobunshi zairyo no kenkyu kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-12-01

    Organosilicon polymers are highly innovative materials having high performance and novel functions, and they can be widely applied. The purpose of this study is to establish fundamental techniques for molecular design, synthesis, material processing and evaluation of organosilicon polymers having excellent electro- and photo-functions, and advanced heat-proof, fire-proof and mechanical properties. This R/D includes (1) R/D of electrical conducting materials by organosilicon polymers, (2) R/D of novel organosilicon polymers applicable to direct lithography, (3) R/D of new silicon-based polymer materials with electro-luminous function, and (4) R/D of silicon-based polymers for new photoconductive materials. In (1), synthesis of highly conjugated polymers is investigated. In (2), novel organosilicon polymeric materials have been developed, which would be applicable to direct lithography of electronic circuits, and which could contribute to simplification of the circuit formation process. In (3), the research aims at development of new silicon-based polymer materials with luminescent function which can be applied to the large size electro-luminescent display devices. In (4), new materials with visible light absorption have been synthesized through the molecular design and synthesis. The photo-carrier generation was observed. 107 refs., 86 figs., 23 tabs.

  16. Research report of FY 1997 on the industrial science and technology development. Technology development of super-metal (technology development of nano-amorphous structural control materials); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku seika hokokusho. Super metal no gijutsu kaihatsu (nano-amorphous kozo seigyo zairyo no gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Research and development of the innovative metals have been conducted, by which the weight reduction of members can be done by drastically improving the strength compared with conventional metals. For the high-rate cluster deposition and super plastic forming technologies, research and development of aluminum-based light-weight materials have been conducted, which provides excellent strength, toughness, and super plastic formability at room temperature. For the high-density energy utilization and control technology (amorphous-A), super-metals have been investigated as high dew point and corrosion resistance materials used for waste incinerators operated under the very severe conditions. These are expected to be applied to the apparatuses and equipment due to their excellent properties. For the controlled cooling technology (amorphous-B), super-metals with excellent soft magnetic characteristics and degree of shape freedom have been investigated for high performance and high efficiency devices including electric/electronic/communication devices, power transmission devices, and various industrial devices and parts. These are expected to contribute to the creation of new markets and the improvement of international competitive force. 123 refs., 160 figs., 33 tabs.

  17. FY 1999 report on the industrial science technology R and D theme - university cooperation type. Technology of glycocluster control biomolecule synthesis (Technology of production of high efficiency oil gathering use sugar chain aggregating agent); 1999 nendo sangyo kagaku gijutsu kenkyu kaihatsu tema (Daigaku renkei gata). Gurikokurasuta seigyo seitai bunshi gosei gijutsu (Koseino sekiyu saishuyo tousa shugokazai seizo gijutsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of developing the synthesis process of new materials which cause no pollution and make the recycle system possible, 'the R and D of technology of synthesis of glycocluster control biomolecules' were carried out, and the FY 1999 results were reported. In 'the technology development of prediction of the functional sugar chain structure,' the stable complex model was deduced from various approaches, and it was made clear that for the leading R and D of new sugar chain medicines, etc., it was extremely important to systematically conduct the analysis of patterns of the interaction between sugar chain ligands and protein receptors and the stable conformation of sugar chain ligands. In 'the technology development of clustering/combination of sugar chains,' the multilateral study was made of a new methodology for designing/constructing purpose-answering cluster molecules essential in sugar chain's expressing high-grade function. Studies were also started of a method to manufacture new biodegradable fiber from not only one-component sugar chains but two-component polysaccharides and of the synthesis of oligosaccharide cluster molecules showing anti-HIV activity. (NEDO)

  18. Fiscal 1997 R and D project on industrial science technology under consignment from NEDO. Report on the R and D of nonlinear optoelectronic materials; 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Hisenkei hikari denshi zairyo no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    As to the development of organic base materials, the paper is going ahead with an evaluation, higher performance and further use as materials of basic optical properties of quirale nonlinear materials and organic conjugate base materials which are promising among organic low molecular materials. As the development of orientation control crystal growth technology, grooves for orientation control were formed on the surface of the lead glass substrate, from which thin film single crystals were obtained. The nonlinear response was studied of the glass where semiconducting fine particles dispersed in matrix glass. Glass scattering base prototype materials were selected by the sol-gel method and ultra-low melting-point glass method. The glass dispersion base materials by the very fast cooling method was also studied. For the purpose of realizing a high speed switching characteristic, a processing technology was developed of ultra fine particle dispersing polymer light waveguide. As to the technology for super lattice, the optimum nonlinear performance materials were selected mainly with the optimum complex super lattice base. Moreover, the three-dimensional super structuring technology was constructed to improve nonlinear optical characteristics. The comprehensive investigational study was conducted for effective promotion of the research development. 177 refs., 260 figs., 27 tabs.

  19. Fiscal 1998 research report on the R and D on industrial science and technology for creating new industries. R and D on intelligent material and structure systems (Development of practical technology for rational use of energy); 1998 nendo shinki sangyo soshutsugata sangyo kagaku gijutsu kenkyu kaihatsu seika hokokusho. Chiteki zairyo kozo system no kenkyu kaihatsu (energy shiyo gorika kankei gijutsu jitsuyoka kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    As a part of development of intelligent material/structure systems, study was made on practical technology for rational use of energy. For resource saving and energy saving (smartening) for large and complex machines and structure systems, light-weight long-life materials/structures are indispensable. Study was thus made on the basic technology of material/structure systems equipped with realtime defect detection function, structural integrity diagnosis function and control function of noise and vibration through information processing and control by integrating composite material/structure and fiber or film sensor material/device. For development of smartening technology, sensing technology was studied to detect the interior structure of composite material/structure compacts. The basic fabrication technology of ceramic actuator materials/devices, and shape memory alloy system actuators were put into development. Smooth connection and cooperation among groups were promoted through the technical committee and research on domestic and overseas trends for forming common knowledge. (NEDO)

  20. Test and survey on a next generation coal liquefying catalyst. Coal molecule scientific test and survey as the base for commercializing the coal liquefying technology; Jisedai sekitan ekika shokubai shiken chosa. Sekitan ekika gijutsu shogyoka kiban to shite no sekitan bunshi kagaku shiken chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The test and survey on a next generation coal liquefying catalyst present a new proposal to raise catalytic activity in coal liquefaction, and perform demonstration experiments in a laboratory scale to search for possibility of developing a new coal liquefying catalyst from various viewpoints. To explain, discussions were given on the catalyst to perform the followings: liquefaction under extremely mild conditions by using ultra strong acids not limited only to metals; ion exchange method and swell carrying method to raise catalyst dispersion very highly, enhance the catalytic activity, and reduce the amount of catalyst to be used; mechanism of producing catalyst activating species to further enhance the activity of iron catalysts; and pursuit of morphological change in the activating species. The coal molecule scientific test and survey as the base for commercializing the coal liquefying technology performed the studies on the following items: pretreatment of coal that can realize reduction of coal liquefaction cost; configuration of the liquefaction reaction, liquefying catalysts, hydrocarbon gas generating mechanism, status of catalysts after liquefaction reaction, and reduction in gas purification cost by using gas separating membranes. Future possibilities were further searched through frank and constructive opinion exchanges among the committee members. (NEDO)

  1. Fiscal 1997 report on the results of the R and D of industrial scientific technology. R and D of synergistic ceramics (R and D of corrosion prevention technology for the petroleum production system); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu seika hokokusho. Synergy ceramics no kenkyu kaihatsu (sekiyu seisan system fushoku boshi gijutsu kenkyu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    To heighten durability and safety of materials/parts for undersea oil drilling, the development of ceramic base materials was made by developing function harmony type process technology which harmonizes on a high grade contrary characteristics and various functions. The paper summed up the fiscal 1997 results. In the design of system formation, computational simulation technology was developed to the composite process and the diploid system. The development of multifunction simultaneous manifestation materials was trially made by the higher nano structure process. A study was made of control of microstructures of porous materials and matrix filling by the gas phase precipitation control. Proposed were selective control of grain growth from species crystals and the columnar particle orientation laminated structure of simultaneous manifestation of strength and toughness. By composite precipitation reaction control, studied were simultaneous dispersion of whisker and increase in density of matrixes, and harmonization with long fibers. Silicon nitride was trially made with low lubrication/friction coefficients and high strength. A simulation method for crack progress behavior evaluation was developed using a testing notched specimen heterogeneous microstructures. Analyses were made of brittle fracture mechanics and reliability evaluation. 273 refs., 344 figs., 29 tabs.

  2. Fiscal 1996 report on the R and D result of industrial science and technology. R and D synergy ceramics (R and D on synergy ceramics); 1996 nendo sangyo kagaku gijutsu kenkyu kaihatsu seika hokokusho. Synergy ceramics no kenkyu kaihatsu (synergy ceramics no kenkyu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper summarizes the general survey mainly conducted by FCRA (Fine Ceramics Research Association) in fiscal 1996, and the joint research results with some universities, from some R and D on synergy ceramics. Silicon nitride based ceramics expressed the same high thermal conductivity as metal by seed crystal addition, grain growth control and orientation control of sheet lamination. For its practical use, study was made on control factors of material, formation and sintering. Ca2Y2Si2O9 single crystal was prepared by float-zone method to determine its crystal structure. No volume change due to high-temperature phase transition as thermal expansion was found. In carbothermal reduction- nitridation of SiO2, addition of Si3N4 seed powder increased a reaction rate and formed uniform particles with an isotropic shape. An average particle size was dependent on the size and number of fine particles in seed powder. Addition of both Si3N4 and Fe compound could change a particle shape from a spherical grain to an elongated grain. A spherical Fe-Si metal grain was found on the tip of an elongated grain. 66 refs., 73 figs., 13 tabs.

  3. Fiscal 1997 R and D project on industrial science and technology under a consignment from NEDO. R and D of the ultimate manipulation technology of atoms and molecules (R and D of the formation of advanced materials for power generation environment); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Genshi bunshi kyokugen sosa gijutsu no kenkyu kaihatsu seika hokokusho (hatsuden kankyoyo kokino sozai keisei gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper describes R and D of the ultimate manipulation technology of atoms and molecules (atom technology). Ten nanoscale Ge islands were successfully formed in proper positions on an Si substrate surface by using mask technology of nanoscale atomic layers. Growth of less-defect ZnSe films on a GaAs(110) surface was possible under various conditions. The magnetic transfer mechanism of Mn oxide with huge reluctance was clarified. Through study on selective-area deposition of Si on plasma-oxidized ultrathin SiO2 mask layers patterned by direct electron-beam exposure and an idea of SiO2/SiNx bilayer mask, direct use of the ultrathin mask layer as insulating layer in device structure was achieved. The superior property as electron beam resist of methano- fullerene composed of fullerene C60 with side chains including oxygen was clarified. The initial oxidation process of an Si(100) surface was analyzed, and the observation result by SREM was theoretically explained. Development of a high-resolution spin polarization electron microscope was also mentioned. 48 refs., 145 figs., 20 tabs.

  4. Report on the results of research and development under a consignment from NEDO of glycoconjugate production utilizing technologies. Development of technologies to fix and effectively utilize carbon dioxide by applying glycoconjugates; 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Fukugo toshitsu seisan riyo gijutsu no kenkyu kaihatsu (fukugo toshitsu oyo nisanka tanso koteika yuko riyo gijutsu kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper reports research results in fiscal 1997 for the `research and development of glycoconjugate production utilizing technologies`. In synthesizing, utilizing and remodeling technologies for glycoconjugates by means of chemical synthesis, studies were performed on developing methods to synthesize Gal {beta}1-3Gal NA(c {alpha})1-0-Serine in preparative scale, synthesizing high mannose type sugars of natural type without protection groups, and linking GlcNA or GalNAc onto partial peptide of fibroblast growth factor (FGF). In synthesizing, utilizing and remodeling technologies for glycoconjugates by using biological methods, studies were carried out, with regard to glycoconjugate synthesizing, utilizing and remodeling technologies utilizing animal cells, on identifying sugar structures of IFN-{gamma} produced from CHO cell line, and isolating CHO cell lines introduced with genes of sugar transferred enzyme GnTIV and/or GnTV. Furthermore, studies were conducted on glycoconjugate synthesizing, utilizing and remodeling technologies utilizing microorganisms, and glycoconjugate structure analyzing technologies. In addition, overall investigation was made on glycoconjugate production utilizing technologies. 113 refs., 76 figs., 18 tabs.

  5. Fiscal 1997 project on the R and D of industrial scientific technology under consignment from NEDO. Report on the results of the R and D of technologies to invent original high-functional materials (technical development of materials to heighten efficiency of power generation facilities); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Dokusoteki kokino zairyo sosei gijutsu no kenkyu kaihatsu (hatsuden shisetsuyo koseinoka zairyo gijutsu kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper described the fiscal 1997 results of the study of the condensation base precise structure control conducted as a technical development of materials to heighten efficiency of power generation facilities. Condensation base polymer is an important material which occupies most of the engineering plastics. The study is aimed at developing basic technologies on the molecular weight and regularity by which a remarkable improvement can be expected in performance of condensation polymerization/ring-opening polymerization polymer materials, polymerization catalyst which arbitarily controls the primary structure such as branch and end group structures, and development of the precision polymerization process. In the synthesis of ordered polymer by direct polycondensation, synthesis of ordered polyamide from asymmetric monomers is studied. In the synthesis of chemically selective polyamide by direct polymerization, polyamide with functional group is synthesized by polymerizing without protecting functional group the monomer with such functional group as causes side reaction in polymerization. In the synthesis of polyamide having the limited distribution of molecular weight, the molecular weight/distribution of polyamide are controlled by connectedly conducting polycondensation which is itself to be done successively. 91 refs., 72 figs., 43 tabs.

  6. Fiscal 1997 R an D project on industrial science and technology under a consignment from NEDO. R and D of the ultimate manipulation technology of atoms and molecules (high-efficiency and analysis and manipulation technology for DNA); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo gijutsu Sogo Kaihatsu Kiko itaku. Genshi bunshi kyokugen sosa gijutsu no kenkyu kaihatsu seika hokokusho (DNA nado kokoritsu kaiseki sosa gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper describes R and D of the ultimate manipulation technology of atoms and molecules (atom technology). Through the observation of super spiral DNA fixed on a spermin or spermidine treated mica substrate by AFM (atomic force microscope), fixation of DNA without any deformation in solution was clarified, and visualization of the spiral structure of DNA were successfully achieved. Manipulation of Xe atoms adsorbed on an Si(111) surface was certainly possible by using STM (scanning tunneling microscope)/atom probe equipment. A nucleation mechanism in crystal growth was studied for various organic source-molecules/GaAs(001) surface systems, and formation of high-density nuclei on the GaAs surface was achieved by accelerating the translational energy of Ga material molecules up to 6eV or more. Ziegler- Natta catalysis important for industrial polymerization of olefin molecules was precisely analyzed by first-principle dynamic simulation. A large-scale simulation of zeolite catalyst is also in promotion for methanol to gasoline conversion. 51 refs., 87 figs., 7 tabs.

  7. Industrial and scientific technology research and development project in fiscal 1997 commissioned by the New Energy and Industrial Technology Development Organization. Research and development of superconducting materials and transistors (report on overall investigation of superconductive devices); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Chodendo zairyo chodendo soshi no kenkyu kaihatsu (chodendo soshika gijutsu kaihatsu seika hokokusho)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper describes development of superconducting new function transistors. Fiscal 1997 as the final year of the project advanced improvement in such transistor-using processes as formation and micro-processing of superconducting thin films to show enhancement in characteristics of high-temperature superconducting transistors and possibility of their application utilizing their high speed motions. Furthermore, fundamental technologies were studied with an aim on junction transistors to be applied as circuits. For field effect transistors, evaluation was performed on critical current distribution of step-type particle boundary junction to make it possible to evaluate characteristics of hundreds of transistors. At the same time, a magnetic flux quantum parametron gate with three-layer structure was fabricated to identify its operation. In superconducting-base transistors, strong reflection was recognized on temperature dependence of permittivity of an Nb-doped strontium titanate substrate used for collectors, by which barrier height was reduced. In the junction transistor and circuit technology, isotropic ramp-edge junctions were fabricated, and so was a frequency divider circuit with single magnetic flux quantum mode operation for evaluating high-speed response characteristics. High time resolution current was observed successfully by using a high-temperature superconducting sampler system. 148 refs., 127 figs., 4 tabs.

  8. Fiscal 1997 project on the R and D of industrial scientific technology under consignment from NEDO. Report on the results of the R and D of silicon-based polymeric materials (development of liquid methane fueled aircraft engine); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo / Shin energy Sangyo gijutsu Sogo Kaihatsu Kiko itaku. Keisokei kobunshi zairyo no kenkyu kaihatsu (methane nenryo kokukiyo engine kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This R and D aims at establishing the basic technology on the molecular design, synthesis, use as materials, and evaluation of silicon-based polymers, of which excellent electronic/optical functions, high heat-resistance/combustion-resistance/dynamic characteristic are expected. The paper introduced the results of the fiscal 1997 R and D of them. The themes are as follows: technology of synthesis of silicon-based polymeric materials with sea-island microstructures, interstitial type structure forming technology, composite materials with organometallic complexes and silicon-based polymers, silicon-based polymer structural materials with ring structures, optimization of the Wurtz`s synthesis method of silicon-based polymers, unsaturated and hypercoordinate organosilicic compounds, function of silicon-based polymers, synthesis and polymerization of new silicon-based monomers, development of a new synthesis method of polysilane and the function, development of new application of silicon-based polymers in imaging devices for recording/memory/display of information, molecular design of {pi}-conjugate and {sigma}-conjugate compounds including silicon, and conformation and electronic state of silicon-based polymeric materials. 186 refs., 141 figs., 68 tabs.

  9. Fiscal 1997 R and D project on industrial science and technology under a consignment from NEDO. R and D of the technology of accelerated formation of bio-functions (R and D of the technology of creation of novel advanced enzymes); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Kasokugata seibutsu kino kochiku gijutsu no kenkyu kaihatsu (shingata kokino koso sosei gijutsu kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper describes R and D on creation technique of novel advanced enzymes. In fiscal 1997, a novel mutagenesis technique was developed to obtain more kinds of mutational genes by shuffling between clonal genes as compared with the previous homogeneous recombination. A genotype- and phenotype-linking technology was developed by expressing random motifs (peptide as components of the active site of protein) on bacteria, and by developing a single-motif protein library. Study was made on a selection system for functional molecules of catalytic activities in a gene level, and a selection system for function of signal transduction. Analysis and evaluation study on vitro experimental technology can be efficiently promoted by recognizing the fitness landscape of target protein molecules. As a result, instead of the conventional method which needs several cycles of mutation and screening of 3-4 week/cycle, an efficient method possible to obtain multiple mutants was established. Research work was also promoted by various organizations to develop an accelerated formation technology of bio-functions. 68 refs., 51 figs., 14 tabs.

  10. Fiscal 1997 project on the R and D of industrial scientific technology under consignment from NEDO. Report on the results of the R and D of technologies to invent original high-functional materials (development of precise structure control materials for enhancement of oil refining); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Dokusoteki kokino zairyo sosei gijutsu no kenkyu kaihatsu (sekiyu seisei kodoka seimitsu kozo seigyo zairyo kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper described the R and D of technologies for creating original high-functional materials under the R and D system of industrial scientific technology. Japan chemical Innovation Institute (JCII) is conducting intensive joint researches under consignment from NEDO with private companies, universities and national research institutes. Among those, the paper reported the fiscal 1997 results of the following two researches conducted as development of precise structure control materials for enhancement of oil refining: precision catalytic polymerization and multi-dimensional space polymer. As to the precision catalytic polymerization, the paper is aimed at developing base technologies for the molecular weight and stereoregularity by which remarkable improvement in performance of addition polymerization type polymer can be expected, and on the development of a polymerization catalyst which arbitarily controls the primary structure such as end group structure and of a precision addition polymerization process. Subthemes are addition polymerization with limit and oriented catalytic polymerization. In relation to multi-dimensional space polymer, the paper is aimed at developing highly selective polymerization technology of aromatic compounds using enzyme related catalysts and synthesis technology of regular structure polymer, and synthesis technology of new polymer group having a new chain pattern except covalent bond/new polymer group having characteristics in three-dimensional space geometric structure. 244 refs,, 160 figs., 94 tabs.

  11. Fiscal 1997 project on the R and D of industrial scientific technology under consignment from NEDO. Report on the results of the R and D of new software structuring models (R and D of micromachine cooperative control use software); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Shin software kozoka model no kenkyu kaihatsu (bisho kikai kyocho seigyoyo software no kenkyu kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A R and D was conducted of software structuring models which ease the development and maintenance of software systems and meet diversification of needs. As for the study of the cooperative control use programming language, a R and D of agent oriented language Flage was carried out for expansion of language function, arrangement of network function, development of exercises, etc. As to the formulation of agent knowledge, proposed were processes to make a program from the specifications, and EVA, a mechanism in response to changes in the specifications of existing programs. In relation to the basic theory of cooperation system, a study was made mainly of object oriented attribute grammar OOAG as a model representing cooperative computation in software process as a rule group. Concerning the study of the situation recognition mechanism, researched were models of communication and reasoning among agents in cooperation. 187 refs., 107 figs., 23 tabs.

  12. FY 1999 report on the results of the project supplementary to the New Sunshine Project - Feasibility of coal hydrogasification technology in China. Investigational study of the social adaptability (Feasibility study of the international cooperation - Report of Beijing Research Institute of Coal Chemistry); 1999 nendo New Sunshine keikaku hojo jigyo (Bessatsu, Kokusai kyoryoku kanosei chosa Pekin Bai kagaku kenkyujo) hokokusho. Sekitan suiso tenka gaska gijutsu kaihatsu - Shakai tekigo sei ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of establishing the coal hydrogasification technology which has a possibility of producing high-quality substitute natural gas in quantity and at low cost, an investigational study of the social adaptability was made. In this fiscal year, the following were carried out: outlook of energy supply/demand in China and the problems, natural gas resource and the plan for the use, actual state of the town gas business and the future plan, etc. As a part of the study, Beijing Research Institute of Coal Chemistry, China Coal Research Institute, made a survey under the research contract. As to the general situation of natural gas in China, report was made on the following: present situation of the development of natural gas resource in China, present situation of town gas in large cities of China, present situation and outlook of coal development and utilization in China, assessment of the coal mine area adaptable to coal hydrogasification, etc. In the survey of the area suitable for coal hydrogasification, report was made on the present situation and future of energy supply/demand in Shanghai, Shanxi, Shenfua and Xinjiang, present situation and future of town gas supply, etc. Survey/report were also made on the coal hydrogasification technology and the applicability. (NEDO)

  13. FY 2000 report on the results of the project supplementary to the New Sunshine Project - Feasibility of coal hydrogasification technology in China. II - Final report. Investigational study of the social adaptability (Feasibility study of the international cooperation - Report of Beijing Research Institute of Coal Chemistry); 2000 nendo New Sunshine keikaku hojo jigyo (Bessatsu kokusai kyoryoku kanosei chosa Pekin Bai kagaku kenkyujo) hokokusho. Sekitan suiso tenka gaska gijutsu kaihatsu - Shakai tekigo sei ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of establishing the coal hydrogasification technology which has a possibility of producing high-quality substitute natural gas in quantity and at low cost, an investigational study of the social adaptability was made. In this fiscal year, the following were carried out: natural gas resource and the plan for the use in China, actual state of the town gas business and the future plan, etc. As a part of the study, Beijing Research Institute of Coal Chemistry, China Coal Research Institute, made a survey under the research contract. As a result of the survey, the following was found out: In Xinjiang and Urumchi, Uigur Autonomous Region, there is an abundant coal resource that is suitable for coal hydrogasification, the transportation pipeline of natural gas had been constructed, and public facilities are prepared, and therefore, both cities are suitable for the construction of coal hydrogasification plant. Datong, Shanxi Province, is a largest city of coal production, enables the long-term coal supply for coal hydrogasification, and has a plan for remodeling of old facilities and construction of new facilities for the introduction of natural gas, and therefore, the city is suitable for the construction of coal hydrogasification plant. (NEDO)

  14. Fiscal 1997 R and D project on industrial science and technology under a consignment from NEDO. R and D of the application technology of functional protein complex (R and D of the high-functional maintenance technology for power plants); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo gijutsu Sogo Kaihatsu Kiko itaku. Kinosei tanpakushitsu shugotai oyo gijutsu no kenkyu kaihatsu (hatsuden shisetsuyo kokino maintenance gijutsu kaihatsu) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    In order to develop advanced maintenance technology for power generation facilities, application technology of functional protein complexes is under investigation. On a light controllable enzymatic reaction system, construction of a light controllable bio-reactor by physico-chemical and bio- chemical techniques, and structure and functions of a photosynthetic protein complex using thermophilic cyanobacteria as material are under investigation. On a molecular mechanism for recognition and reaction of receptor proteins, structure analysis and engineering application of glutamate receptor channels of a synaptic transmission system, and basic study and material proteins for artificial structures using endocytic micromachinery, and a multi-enzyme system for synthesis of glycosphingolipids are under investigation. On a complex oxidation/reduction system by genetic engineering technique, construction of a high- efficiency stable system with functionally arranged oxidoreductase and electron transmission systems in biomembranes is in promotion. Research work was also made on molecular assemblies for a functional protein system. 166 refs., 91 figs., 9 tabs.

  15. スポーツ科学論序説(II) : イメージの生成 : 我が国におけるスポーツ科学の誕生

    OpenAIRE

    Higuchi, Satoshi

    1996-01-01

    (1) The discourse concerning sport science makes the images and/or myths of sport and science begin to work. (2) The term supōtsu-kagaku or sport science publicly appeared in 1960s in Japan. We can find, however, the scientific attention to sports or physical movements already around 1900. A remarkable organization of the knowledge of sport science was realized in 1930s at the National Institute of Physical Education. The main research of the science was sports medicine, so the sport scie...

  16. Fiscal 1997 project on the R and D of industrial scientific technology under consignment form NEDO. Report on the results of the R and D of technologies to invent original high-functional materials (technical development of structure control materials / R and D of molecular harmonized materials); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Dokusoteki kokino zairyo sosei gijutsu no kenkyu kaihatsu (kozo seigyo zairyo gijutsu kaihatsu) bunshi kyocho zairyo no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    By establishing microtechnology using molecular-level bottoming-up (molecular harmonization) by imitating the system of living organism, the paper described the R and D of molecular harmonized materials aiming at developing high-functional/high-performance materials such as high-performance catalyst, photo-information functional materials and sensing materials. Under consignment from NEDO, Japan Chemical innovation Institute started the 5-year plan in fiscal 1997. Self-assembled molecular films, in which organic molecules are orderly arranged by self-assembly, aim at developing new memory/optical/sensing materials. Mesophase materials which are such materials as liquid crystal showing the intermediate state between solid and liquid, develop optical/photoconductive materials using precise molecular orientation controllability. Macroporous materials are such substances as zeolite having molecular size micro pores. The paper aims at establishment of synthesis techniques of them and development of high-performance catalyst, etc. using them. In the comprehensive investigational research, conducted was a survey of the trend overseas in addition to a study of subjects in question. Further, the supporting basic study was reconsigned to universities, etc. 57 refs., 62 figs., 17 tabs.

  17. Fiscal 1997 project on the R and D of industrial scientific technology under consignment from NEDO. Report on the results of the R and D of technologies to invent original high-functional materials (technical development of structure control materials / R and D of multi-stimuli-responsive materials); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Dokusoteki kokino zairyo sosei gijutsu no kenkyu kaihatsu (kozo seigyo zairyo gijutsu kaihatsu) kodo shigeki oto zairyo no kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper described multi-stimuli-responsive materials out of the technology developments for creating original high-functional materials under the system of R and D of industrial scientific technologies. These are materials which repeatedly reproduce functions such as separation, penetration and movement in response to stimuli by imitating living organisms. In relation to polymer multi-stimuli-responsive materials, various copolymers were synthesized using N-acetyl (meta) acrylamide, of which the synthesis method was established in the previous fiscal year, as a main component, and thermal responsive polymer with upper critical solution temperature which becomes a base of separation functional materials was searched for. By immobilizing it with molecular recognition ligand, measured was thermal dependence of affinity of the immobilized matter to albumin. Also studied were molecular recognition cell adhesion/separation functional materials. Concerning composite multi-stimuli-responsive materials, with the use of silica microcapsule surface-immobilized with silane coupling agent, studied were the optimum conditions for immobilizing thermo-responsive polymer to the surface of the capsule. Using motion functional materials by ion exchange resin, obtained was motion functionality which is satisfactory at the state of practical use. 94 refs., 82 figs., 16 tabs.

  18. Industrial and scientific technology research and development project fiscal 1997 commissioned by the New Energy and Industrial Technology Development Organization. Report on research and development of a brain type computer architecture `trial fabrication and high-level evaluation on chips for a large-scale artificial neural system` and on results of evaluation studies on the chips; 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Nogata computer architecture no kenkyu kaihatsu `daikibo jinko shinkei kairo system yo chip no shisaku to kodo hyoka` chip hyoka kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    In order to develop a brain type computer architecture, a brain mimic processor (BMP) has been developed (which was made in LSI in fiscal 1997), and studies are being made on developing its applications. Development has been made on an element in which linkage of one million cells with one thousand neural cells can be realized. Evaluation substrates mounted with the BMP, control software, and compilers were provided to 15 organizations including the National Research Institutes, universities, corporations, and other societies (for 19 themes) to evaluate capability of the LSI and its application development. All of the research organizations are using these items utilizing features of the LSI or the network for such purposes as learning, storage, recognition and control. The applicable theme may include infrared spectrum pattern recognition and domain division of document images using neural network functions. It can also include structural analysis of mass spectrum molecules, time series pattern recognition, location of corresponding points in images, estimation of moving images, satellite control, character recognition, short time storage, long-term association memory models, and invention process studies, all utilizing the functions of the BMP. 71 refs., 89 figs., 9 tabs.

  19. Chimpanzee pinworm, Enterobius anthropopitheci (Nematoda: Oxyuridae), maintained for more than twenty years in captive chimpanzees in Japan.

    Science.gov (United States)

    Hasegawa, Hideo; Udono, Toshifumi

    2007-08-01

    The chimpanzee pinworm, Enterobius anthropopitheci (Gedoelst, 1916), was found in chimpanzees, Pan troglodytes, reared in Kumamoto Primate Research Park, Sanwa Kagaku Kenkyusho Co., Ltd., Kumamoto, Japan, in 2006. Because the chimpanzees in this institution originated from chimpanzees imported from Africa before 1984, it is considered that E. anthropopitheci infection has persisted for more than 20 yr in the chimpanzees. Analysis of pinworm specimens preserved in the institution revealed that transition of predominant pinworm species occurred, responding to the change of anthelmintics used for pinworm treatment. Present dominance of E. anthropopitheci is surmised to be caused by fenbendazole, which has been adopted from 2002. Scarcity of mixed infection with E. anthropopitheci and Enterobius vermicularis suggests interspecific competition between the pinworms. PMID:17918364

  20. [Phantom Study on Dose Reduction Using Iterative Reconstruction in Low-dose Computed Tomography for Lung Cancer Screening].

    Science.gov (United States)

    Minehiro, Kaori; Takata, Tadanori; Hayashi, Hiroyuki; Sakuda, Keita; Nunome, Haruka; Kawashima, Hiroko; Sanada, Shigeru

    2015-12-01

    We investigated dose reduction ability of an iterative reconstruction technology for low-dose computed tomography (CT) for lung cancer screening. The Sinogram Affirmed Iterative Reconstruction (SAFIRE) provided in a multi slice CT system, Somatom Definition Flash (Siemens Healthcare) was used. An anthropomorphic chest phantom (N-1, Kyoto Kagaku) was scanned at volume CT dose index (CTDIvol) of 0.50-11.86 mGy with 120 kV. For noise (standard deviation) and contrast-to-noise ratio (CNR) measurements, CTP486 and CTP515 modules in the Catphan (The Phantom Laboratory) were scanned. Radiological technologists were participated in the perceptual comparison. SAFIRE reduced the SD values by approximately 50% compared with filter back projection (FBP). The estimated dose reduction rates by SAFIRE determined from the perceptual comparison was approximately 23%, while 75% dose reduction rate was expected from the SD value reduction of 50%. PMID:26685831

  1. Increase of body surface temperature and blood flow by theanine

    International Nuclear Information System (INIS)

    Suntheanine (Taiyo Kagaku Co.: Theanine) is the trade name for L-theanine which is a unique amino acid found almost solely in tea plants, responsible for the exotictaste of green tea. We investigated the effects of relate to relaxation, improves the taste of processed foods, radiation sensitization, and increase of body surface temperature in vivo study. The results of the present study confirmed, (1) Suntheanine is incorporated into the brain and induces the emission of α -waves an induced of relaxation. (2) Body surface temperature and blood flow on skin were increased after administration of Suntheanine. (3) There was effects of radiation sensitization in whole body irradiation of X-rays after Suntheanine IP injection on C3H mice. (4) Acute toxicity, subacute toxicity and mutagen testconfirm the safety Suntheanine in this study

  2. Increase of body surface temperature and blood flow by theanine

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, Takeo; Noguchi, Kenichi; Ando, Satoshi [Suzuka, Univ. of Medical Science, Suzuka (Japan)] [and others

    2002-07-01

    Suntheanine (Taiyo Kagaku Co.: Theanine) is the trade name for L-theanine which is a unique amino acid found almost solely in tea plants, responsible for the exotictaste of green tea. We investigated the effects of relate to relaxation, improves the taste of processed foods, radiation sensitization, and increase of body surface temperature in vivo study. The results of the present study confirmed, (1) Suntheanine is incorporated into the brain and induces the emission of {alpha} -waves an induced of relaxation. (2) Body surface temperature and blood flow on skin were increased after administration of Suntheanine. (3) There was effects of radiation sensitization in whole body irradiation of X-rays after Suntheanine IP injection on C3H mice. (4) Acute toxicity, subacute toxicity and mutagen testconfirm the safety Suntheanine in this study.

  3. Entamoeba dispar, but not E. histolytica, detected in a colony of chimpanzees in Japan.

    Science.gov (United States)

    Tachibana, H; Cheng, X J; Kobayashi, S; Fujita, Y; Udono, T

    2000-07-01

    Chimpanzees (Pan troglodytes) residing in the Kumamoto Primate Research Park, Sanwa Kagaku Kenkyusho, were surveyed for the presence of intestinal parasites. Stool samples from 107 chimpanzees were examined by microscopy after formalin-ether sedimentation. Of these animals, 100 were infected with at least 1 species of ameba. The positivity rates recorded were as follows: Entamoeba coli, 88%; E. histolytica/E. dispar, 48%; E. hartmanni, 15%; Iodamoeba buetschlii, 8%; Endolimax nana, 4%; and Entamoeba chattoni, 2%. Polymerase chain reaction (PCR) analysis to distinguish between E. histolytica and E. dispar was performed on these samples. E. dispar DNA was detected in 60 of 107 samples (56%), including 9 that had been microscopically determined to be negative for E. histolytica/ E. dispar. In contrast, no E. histolytica DNA was detected in the 107 samples. Zymodeme analysis indicated that 10 isolates were E. dispar. When 104 chimpanzees were examined serologically for E. histolytica infection, 1 sample was scored as positive by indirect hemagglutination and another was found to be positive by an indirect fluorescent antibody test. However, both specimens were borderline-positive and were clearly negative in other tests, suggesting that they might be false-positives. These results demonstrate that the pathogenic E. histolytica was absent in this colony, regardless of the high degree of prevalence of other amebas. For an accurate diagnosis, PCR analysis is recommended in addition to microscopic examination. PMID:10935902

  4. Studies on the radiation exposure and protection at the X-ray radiography in the medical care at home

    International Nuclear Information System (INIS)

    Since there are scarce studies on the exposure and protection at the radiography in the medical care at home, authors performed such studies as comparison of doses from self-rectifying and inverter tubes, exposure and protection to patients and nursing persons and actual measurement (October, 1997) at home in Tohno city, Iwate prefecture, of scattering radiation dose at radiography. Apparatuses used were: Portable X-ray equipments; self-rectifying types (Toshiba TR-20 and Medisonacoma PX 30N) and an inverter type (Medisonacoma PX-15HF), Kyoto Kagaku WAC water phantom, X-ray analyzer Model 200 of Kasei Optonics, and Dosimeters (Victoreen Radocon ionization dosimeter and Aloka ICS-301 ionization chamber survey meters). Radiation qualities, surface doses and scattering doses of the equipments under various conditions were compared by the half value layer and effective energy measured with the analyzer. Actual measurement of scattering dose was done at home for 4 patients at chest radiography. Annual dose in monthly ordinary radiography at home, when the distance was >200 cm far from the flux center, was found about 1/100 of 1 mSv (the annual public dose limit), thus securing the safety of nurses. (K.H.)

  5. Development and comparison of projection and image space 3D nodule insertion techniques

    Science.gov (United States)

    Robins, Marthony; Solomon, Justin; Sahbaee, Pooyan; Samei, Ehsan

    2016-04-01

    This study aimed to develop and compare two methods of inserting computerized virtual lesions into CT datasets. 24 physical (synthetic) nodules of three sizes and four morphologies were inserted into an anthropomorphic chest phantom (LUNGMAN, KYOTO KAGAKU). The phantom was scanned (Somatom Definition Flash, Siemens Healthcare) with and without nodules present, and images were reconstructed with filtered back projection and iterative reconstruction (SAFIRE) at 0.6 mm slice thickness using a standard thoracic CT protocol at multiple dose settings. Virtual 3D CAD models based on the physical nodules were virtually inserted (accounting for the system MTF) into the nodule-free CT data using two techniques. These techniques include projection-based and image-based insertion. Nodule volumes were estimated using a commercial segmentation tool (iNtuition, TeraRecon, Inc.). Differences were tested using paired t-tests and R2 goodness of fit between the virtually and physically inserted nodules. Both insertion techniques resulted in nodule volumes very similar to the real nodules (<3% difference) and in most cases the differences were not statistically significant. Also, R2 values were all <0.97 for both insertion techniques. These data imply that these techniques can confidently be used as a means of inserting virtual nodules in CT datasets. These techniques can be instrumental in building hybrid CT datasets composed of patient images with virtually inserted nodules.

  6. History of T-cain: a local anesthetic developed and manufactured in Japan.

    Science.gov (United States)

    Tobe, Masaru; Saito, Shigeru

    2015-10-01

    In many anesthesia textbooks written in English, lidocaine, tetracaine, bupivacaine, ropivacaine, and chloroprocaine are listed as useful local anesthetics for spinal anesthesia. In contrast, T-cain is not included in these lists, even though it has been reported to be suitable for spinal anesthesia in Japan. T-cain was developed as a local anesthetic in the early 1940s by Teikoku Kagaku Sangyo Inc. in Itami, Japan, by replacing a methyl group on tetracaine (Pantocaine(®)) with an ethyl group. T-cain was clinically approved for topical use in Japan in November 1949, and a mixture of dibucaine and T-cain (Neo-Percamin S(®)) was approved for spinal use in May 1950. Simply because of a lack of foreign marketing strategy, T-cain has never attracted global attention as a local anesthetic. However, in Japan, T-cain has been used topically or intrathecally (as Neo-Percamin S(®)) for more than 60 years. Other than the side effects generally known for all local anesthetics, serious side effects have not been reported for T-cain. In fact, several articles have reported that T-cain decreases the neurotoxicity of dibucaine. In this historical review, the characteristics of T-cain and its rise to become a major spinal anesthetic in Japan are discussed. PMID:26302690

  7. Amla (Emblica officinalis Gaertn.) extracts reduce oxidative stress in streptozotocin-induced diabetic rats.

    Science.gov (United States)

    Rao, T P; Sakaguchi, N; Juneja, L R; Wada, E; Yokozawa, T

    2005-01-01

    The antioxidant properties of amla extracts and their effects on the oxidative stress in streptozotocin-induced diabetes were examined in rats. Amla in the form of either the commercial enzymatic extract SunAmla (Taiyo Kagaku Co. Ltd., Yokkaichi, Japan) (20 or 40 mg/kg of body weight/day) or a polyphenol-rich fraction of ethyl acetate extract (10 or 20 mg/kg of body weight/day) was given orally for 20 days to the streptozotocin-induced diabetic rats. Amla extracts showed strong free radical scavenging activity. Amla also showed strong inhibition of the production of advanced glycosylated end products. The oral administration of amla extracts to the diabetic rats slightly improved body weight gain and also significantly alleviated various oxidative stress indices of the serum of the diabetic rats. The elevated serum levels of 5-hydroxymethylfurfural, which is a glycosylated protein that is an indicator of oxidative stress, were significantly reduced dose-dependently in the diabetic rats fed amla. Similarly, the serum level of creatinine, yet another oxidative stress parameter, was also reduced. Furthermore, thiobarbituric acid-reactive substances levels were significantly reduced with amla, indicating a reduction in lipid peroxidation. In addition, the decreased albumin levels in the diabetic rats were significantly improved with amla. Amla also significantly improved the serum adiponectin levels. These results form the scientific basis supporting the efficacy of amla for relieving the oxidative stress and improving glucose metabolism in diabetes. PMID:16176148

  8. An automatic controlled field size of a γ-ray irradiation system

    International Nuclear Information System (INIS)

    We constructed a γ-ray irradiation system with a commercial irradiation instrument, Sangyo Kagaku Co. Ltd., Model SK-951. The system is composed of an irradiator mounted with 60Co (3.7 GBq) and 137Cs (11.1 GBq and 111 GBq), and a mobile exposure deck having a lead shield sandwiched with iron (1200 mm(W) x 1200 mm(H) x 50 mm(D)) at back side. This shield provides low exposure rate at wall, floor and ceiling in the present room. To limit irradiation field size within dimension of the shield, three kinds of square collimator (6.03deg, 9.27deg and 20.02deg) were equipped around the irradiator beam exit. The selection of collimators is automatically controlled. The abilities of shield and collimator were evaluated by calculation and measurement of exposure rate at points on the wall. By these improvements, exposure rate was lowered to the dose-equivalent limit in law. (author)

  9. A study of exposure dose reduction in cineless cardiac catheterization

    International Nuclear Information System (INIS)

    In cardiac catheterization, in what extent the cineless procedure reduces the radiation exposure dose to patients and room scattering was examined in comparison with the ordinary procedure (cine- and digital-procedure). Apparatuses were Siemens BICOR HS/HICOR, Polydoros and Toshiba Super G/DFP2000A, KXO-80C/D. For measuring the exposure dose to patients, TLD devices (Kasei Optonics Ltd.) were inserted in the regions of lens, thyroid, petrosa, liver, genital organ, chest wall and back of the phantom (Kyoto Kagaku Ltd.), which was exposed according to the cine- or digital-procedure for cardiac catheterization at the routine angulation. For the dose to the operator, the phantom, placed at the operation site, with the devices was exposed similarly. Scattering radiation was measured with an ionizing chamber-survey meter ICS-311 (ALOKA Ltd.) and dosemeter NOMEX (Toyo Medics Ltd.). Cineless procedure was found to reduce the exposure dose to patients to 30-50% and to the operator to 50%, and the scattering radiation dose to 25%. (K.H.)

  10. Contamination profiles of short-chain polychlorinated n-alkanes in foodstuff samples from Japan

    Energy Technology Data Exchange (ETDEWEB)

    Matsukami, Hidenori; Kurunthachalam, S.; Ohi, Etsumasa; Takasuga, Takumi [Shimadzu Techno Research, Inc., Kyoto (Japan); Iino, Fukuya; Nakanishi, Junko [National Inst. of Advanced Industrial Science and Technology, Tsukuba (Japan)

    2004-09-15

    Polychlorinated n-alkanes (PCAs) are group of chemicals manufactured by chlorination of liquid n-paraffin or paraffin wax that contain 30 to 70% chlorine by weight. Large amounts of PCAs are widely used as plasticizers for vinyl chloride, lubricants, paints, and flame retardants and number of other industrial applications. Annual global production of PCAs is approximately 300 kilo tones, with a majority having medium-carbon-chain (C14-C19) length. According to the investigation made by Kagaku Kogyo Nippon-Sha, the annual consumption of PCAs in Japan was about 83,000 tons in between 1986-2001. Short-carbon-chain (C10-C13) has been placed on the Priority Substance List under Canadian Environmental Protection Act and on the Environmental Protection Agency Toxic Release Inventory in the USA due to its potential to act as tumor promoters in mammals. Data on environment levels of PCAs is meager, nevertheless, PCAs have been measured at relatively high concentrations in biota from Sweden, biota, sediment from Canada and marine biota and human milk from the Canadian Arctic. In our earlier study, we reported concentrations of short-chain PCAs from sewage treatment plant (STP) collected from Tama River, Tokyo and river water and sediment from Tokyo and Osaka. STP influent water contained greater shortchain PCAs concentrations than STP effluent. In addition, some river water and sediment samples contained detectable concentrations of short-chain PCAs, which was similar to other industrial countries. However, there is no study conducted to explore the contamination profiles of short-chain PCAs in human foodstuff samples. In the present study, we analyzed eleven foodstuff samples that were purchased from various supermarkets in order to know the short-chain PCAs concentrations in the foodstuff and possible human total daily intake (TDI) amounts.

  11. Construction of the quantitative analysis environment using Monte Carlo simulation

    International Nuclear Information System (INIS)

    The thoracic phantom image was acquisitioned of the axial section to construct maps of the source and density with Monte Carlo (MC) simulation. The phantom was Heart/Liver Type HL (Kyoto Kagaku Co., Ltd.) single photon emission CT (SPECT)/CT machine was Symbia T6 (Siemence) with the collimator LMEGP (low-medium energy general purpose). Maps were constructed from CT images with an in-house software using Visual studio C Sharp (Microsoft). The code simulation of imaging nuclear detectors (SIMIND) was used for MC simulation, Prominence processor (Nihon Medi-Physics) for filter processing and image reconstruction, and the environment DELL Precision T7400 for all image processes. For the actual experiment, the phantom was given 15 MBq of 99mTc assuming the uptake 2% at the dose of 740 MBq in its myocardial portion and SPECT image was acquisitioned and reconstructed with Butter-worth filter and filter back projection method. CT images were similarly obtained in 0.3 mm thick slices, which were filed in one formatted with digital imaging and communication in medicine (DICOM), and then processed for application to SIMIND for mapping the source and density. Physical and mensuration factors were examined in ideal images by sequential exclusion and simulation of those factors as attenuation, scattering, spatial resolution deterioration and statistical fluctuation. Gamma energy spectrum, SPECT projection and reconstructed images given by the simulation were found to well agree with the actual data, and the precision of MC simulation was confirmed. Physical and mensuration factors were found to be evaluable individually, suggesting the usefulness of the simulation for assessing the precision of their correction. (T.T.)

  12. Estimation of exposed radiation dose in radiography of the chest. Mainly on the dose at health examination on automobiles

    International Nuclear Information System (INIS)

    The exposure doses in radiography and photofluorography of the chest at health examination on automobiles were estimated and compared with those using other hospital equipments. The tube voltage, effective energy and half value layer under ordinary conditions for radiography and fluorography were measured by KYOKKO model 100 X-ray analyzer and output pulse shape was confirmed by the fluorometer (TOREKEY-1001 C). The dose at the body surface was measured by the ionization chambers (VICTOREEN RADCON 500 and 30-330) which had been equipped in the WAC chest phantom (JIS Z 4915, Kyoto Kagaku). Nine automobiles of 3 facilities were used, of which X-ray generating apparatuses of either condenser or inverter type were manufactured by Hitachi (5 machines), Toshiba (1) and Shimadzu (3). The examined apparatuses not for the automobile were Toshiba-20 and Hitachi SIRIUS-100 portable ones and Hitachi DH-1520 TM high-voltage one. The effective energy was found dependent on the tube voltage (100-130 kV) and X-ray generating system (35.1-54.37 keV in the condenser type and 41.1-43.9 keV in the inverter type). Pulse shape analysis revealed that the pulse height and area under the pulse height-time curve were larger in the inverter system. The mean doses in photofluorography and radiography on automobiles were 0.525 and 0.297 mGy, respectively. The mean dose of 0.61 mGy in radiography at home with the portable apparatus was the highest even when compared with that of 0.525 mGy for fluorography on the automobile. Thus, the inverter system on the car can guarantee the level of 0.4 mGy defined by IAEA guideline (Safety series No. 115, 1996). (K.H.)

  13. CT x-ray tube voltage optimisation and image reconstruction evaluation using visual grading analysis

    Science.gov (United States)

    Zheng, Xiaoming; Kim, Ted M.; Davidson, Rob; Lee, Seongju; Shin, Cheongil; Yang, Sook

    2014-03-01

    The purposes of this work were to find an optimal x-ray voltage for CT imaging and to determine the diagnostic effectiveness of image reconstruction techniques by using the visual grading analysis (VGA). Images of the PH-5 CT abdomen phantom (Kagaku Co, Kyoto) were acquired by the Toshiba Aquillion One 320 slices CT system with various exposures (from 10 to 580 mAs) under different tube peak voltages (80, 100 and 120 kVp). The images were reconstructed by employing the FBP and the AIDR 3D iterative reconstructions with Mild, Standard and Strong FBP blending. Image quality was assessed by measuring noise, contrast to noise ratio and human observer's VGA scores. The CT dose index CTDIv was obtained from the values displayed on the images. The best fit for the curves of the image quality VGA vs dose CTDIv is a logistic function from the SPSS estimation. A threshold dose Dt is defined as the CTDIv at the just acceptable for diagnostic image quality and a figure of merit (FOM) is defined as the slope of the standardised logistic function. The Dt and FOM were found to be 5.4, 8.1 and 9.1 mGy and 0.47, 0.51 and 0.38 under the tube voltages of 80, 100 and 120 kVp, respectively, from images reconstructed by the FBP technique. The Dt and FOM values were lower from the images reconstructed by the AIDR 3D in comparison with the FBP technique. The optimal xray peak voltage for the imaging of the PH-5 abdomen phantom by the Aquillion One CT system was found to be at 100 kVp. The images reconstructed by the FBP are more diagnostically effective than that by the AIDR 3D but with a higher dose Dt to the patients.

  14. A field study to determine the prevalence, dairy herd management systems, and fresh cow clinical conditions associated with ketosis in western European dairy herds.

    Science.gov (United States)

    Berge, Anna C; Vertenten, Geert

    2014-01-01

    The aim of this study was to determine the prevalence, major management systems, and fresh cow clinical conditions associated with ketosis in western European dairy herds. A total of 131 dairies were enrolled in Germany, France, Italy, the Netherlands, and the United Kingdom during 2011 to 2012. A milk-based test for ketones (Keto-Test; Sanwa Kagaku Kenkyusho Co. Ltd., Nagoya, Japan; distributed by Elanco Animal Health, Antwerp, Belgium) was used for screening cows between d 7 and 21 after calving and ketosis was defined as a Keto-Test ≥100µmol/L. Study cows were observed for clinical disease up to 35d postcalving. Multivariate analysis (generalized estimating equation logistic regression) was performed to determine country, farm, management, feed, and cow factors associated with ketosis and to determine associations between ketosis and fresh cow diseases. Thirty-nine percent of the cows were classified as having ketosis. The herd average of ketosis was 43% in Germany, 53% in France, 31% in Italy, 46% in the Netherlands, and 31% in the United Kingdom. Of the 131 farms, 112 (85%) had 25% or more of their fresh cows resulting as positive for ketosis. Clinical ketosis was not reported in most farms and the highest level of clinical ketosis reported was 23%. The risks of ketosis were significantly lower in Italy and the United Kingdom compared with France, the Netherlands, and Germany. Larger herd size was associated with a decreased risk of ketosis. The farms that fed partially mixed rations had 1.5 times higher odds of ketosis than those that fed total mixed rations. Cows that calved in April to June had the highest odds of ketosis, with about twice as high odds compared with cows that calved in July to September. The cows that calved in January to March tended to have 1.5 times higher risk of ketosis compared with cows that calved in July to September. The odds of ketosis in parity 2 and parity 3 to 7 was significantly higher (1.5 and 2.8 times higher

  15. SU-E-I-22: Dependence On Calibration Phantom and Field Area of the Conversion Factor Used to Calculate Skin Dose During Neuro-Interventional Fluoroscopic Procedures

    Energy Technology Data Exchange (ETDEWEB)

    Rana, V K; Vijayan, S [Physiology and Biophysics, Toshiba Stroke and Vascular Research Center, University at Buffalo (State University of New York), Buffalo, NY (United States); Rudin, S R; Bednarek, D R [Department of Radiology, Physiology and Biophysics, Toshiba Stroke and Vascular Research Center, University at Buffalo (State University of New York), Buffalo, NY (United States)

    2014-06-01

    Purpose: To determine the appropriate calibration factor to use when calculating skin dose with our real-time dose-tracking system (DTS) during neuro-interventional fluoroscopic procedures by evaluating the difference in backscatter from different phantoms and as a function of entrance-skin field area. Methods: We developed a dose-tracking system to calculate and graphically display the cumulative skin-dose distribution in real time. To calibrate the DTS for neuro-interventional procedures, a phantom is needed that closely approximates the scattering properties of the head. We compared the x-ray backscatter from eight phantoms: 20-cm-thick solid water, 16-cm diameter water-filled container, 16-cm CTDI phantom, modified-ANSI head phantom, 20-cm-thick PMMA, Kyoto-Kagaku PBU- 50 head, Phantom-Labs SK-150 head, and RSD RS-240T head. The phantoms were placed on the patient table with the entrance surface at 15 cm tube-side from the isocenter of a Toshiba Infinix C-arm, and the entrance-skin exposure was measured with a calibrated 6-cc PTW ionization chamber. The measurement included primary radiation, backscatter from the phantom and forward scatter from the table and pad. The variation in entrance-skin exposure was also measured as a function of the skin-entrance area for a 30x30 cm by 20-cm-thick PMMA phantom and the SK-150 head phantom using four different added beam filters. Results: The entranceskin exposure values measured for eight different phantoms differed by up to 12%, while the ratio of entrance exposure of all phantoms relative to solid water showed less than 3% variation with kVp. The change in entrance-skin exposure with entrance-skin area was found to differ for the SK-150 head compared to the 20-cm PMMA phantom and the variation with field area was dependent on the added beam filtration. Conclusion: To accurately calculate skin dose for neuro-interventional procedures with the DTS, the phantom for calibration should be carefully chosen since different

  16. SU-E-I-22: Dependence On Calibration Phantom and Field Area of the Conversion Factor Used to Calculate Skin Dose During Neuro-Interventional Fluoroscopic Procedures

    International Nuclear Information System (INIS)

    Purpose: To determine the appropriate calibration factor to use when calculating skin dose with our real-time dose-tracking system (DTS) during neuro-interventional fluoroscopic procedures by evaluating the difference in backscatter from different phantoms and as a function of entrance-skin field area. Methods: We developed a dose-tracking system to calculate and graphically display the cumulative skin-dose distribution in real time. To calibrate the DTS for neuro-interventional procedures, a phantom is needed that closely approximates the scattering properties of the head. We compared the x-ray backscatter from eight phantoms: 20-cm-thick solid water, 16-cm diameter water-filled container, 16-cm CTDI phantom, modified-ANSI head phantom, 20-cm-thick PMMA, Kyoto-Kagaku PBU- 50 head, Phantom-Labs SK-150 head, and RSD RS-240T head. The phantoms were placed on the patient table with the entrance surface at 15 cm tube-side from the isocenter of a Toshiba Infinix C-arm, and the entrance-skin exposure was measured with a calibrated 6-cc PTW ionization chamber. The measurement included primary radiation, backscatter from the phantom and forward scatter from the table and pad. The variation in entrance-skin exposure was also measured as a function of the skin-entrance area for a 30x30 cm by 20-cm-thick PMMA phantom and the SK-150 head phantom using four different added beam filters. Results: The entranceskin exposure values measured for eight different phantoms differed by up to 12%, while the ratio of entrance exposure of all phantoms relative to solid water showed less than 3% variation with kVp. The change in entrance-skin exposure with entrance-skin area was found to differ for the SK-150 head compared to the 20-cm PMMA phantom and the variation with field area was dependent on the added beam filtration. Conclusion: To accurately calculate skin dose for neuro-interventional procedures with the DTS, the phantom for calibration should be carefully chosen since different

  17. Quantitative comparison of commercial and non-commercial metal artifact reduction techniques in computed tomography.

    Directory of Open Access Journals (Sweden)

    Dirk Wagenaar

    Full Text Available Typical streak artifacts known as metal artifacts occur in the presence of strongly attenuating materials in computed tomography (CT. Recently, vendors have started offering metal artifact reduction (MAR techniques. In addition, a MAR technique called the metal deletion technique (MDT is freely available and able to reduce metal artifacts using reconstructed images. Although a comparison of the MDT to other MAR techniques exists, a comparison of commercially available MAR techniques is lacking. The aim of this study was therefore to quantify the difference in effectiveness of the currently available MAR techniques of different scanners and the MDT technique.Three vendors were asked to use their preferential CT scanner for applying their MAR techniques. The scans were performed on a Philips Brilliance ICT 256 (S1, a GE Discovery CT 750 HD (S2 and a Siemens Somatom Definition AS Open (S3. The scans were made using an anthropomorphic head and neck phantom (Kyoto Kagaku, Japan. Three amalgam dental implants were constructed and inserted between the phantom's teeth. The average absolute error (AAE was calculated for all reconstructions in the proximity of the amalgam implants.The commercial techniques reduced the AAE by 22.0±1.6%, 16.2±2.6% and 3.3±0.7% for S1 to S3 respectively. After applying the MDT to uncorrected scans of each scanner the AAE was reduced by 26.1±2.3%, 27.9±1.0% and 28.8±0.5% respectively. The difference in efficiency between the commercial techniques and the MDT was statistically significant for S2 (p=0.004 and S3 (p<0.001, but not for S1 (p=0.63.The effectiveness of MAR differs between vendors. S1 performed slightly better than S2 and both performed better than S3. Furthermore, for our phantom and outcome measure the MDT was more effective than the commercial MAR technique on all scanners.

  18. Determination of trace amount of SDS surfactant by Oxtractionspectrophotometric method

    International Nuclear Information System (INIS)

    Complete text of publication follows. Sodium dodecylsulfate (SDS) is linear surfactant that widely used in detergent formulations such as dishwashing liquids, hair and body shampoos etc. Various analytical techniques have been reported for the determination of SDS including capillary electrophoresis/mass spectrometry (Y. Tanaka et al., Bunseki Kagaku Abstract, 1998, Vol. 47. No. 9.), turbidimetry (M. L. Fielden et al., Journal of Colloid and Interface Science, 198 (1998), 261-265.). and polarographic method. (S. Hiromiti, et al., Japan Analyst, 38(1989), 288-291.). A simple, sensitive extraction-spectrophotometric method for determination of trace amounts of sodium dodecyl sulfate (SDS) is reported.The (SDS--OTB+) ion-pair in buffered media is quantitatively extracted into di-chloromethane and its absorbance is measured at 625 nm in room temperature.The effect of different variables such as solvent, volume of extractant, volume of cationic reagent, pH, shaking time is investigated and optimum conditions for quantitative extraction of SDS is obtained. Linear calibration curve over the SDS concentration range of 0.14 μg mL-1 and regression coefficient of 0.9996 is obtained.The relative standard deviation (RSD) of seven replicate determinations of SDS concentrations of 0.2 μg mL-1 , 1 μg mL-1 and 4 μg mL-1 is 3.75%, 1.84% and 0.63% respectively. The detection limit of the method is 8.91 ng mL-1.The amount of SDS in Karoon river as real sample is determined by standard addition method which is 0.141 μg mL-1.The interference of 22 cationic and anionic species have also been evaluated and it was found that most species have no effect on the extraction selectivity. The method was applied to the Karoon river raw water contaminated with industrial and house savages. The results showed high potential of the recommended method for the determination of SDS in water samples. The authors gratefully acknowledge the financial support of this work by Ahwaz Petroleum Faculty

  19. Adequate cutoff frequency of the prefilter in quantification of regional cerebral blood flow using 123I-IMP

    International Nuclear Information System (INIS)

    The effect of cutoff frequency (CF) of the butterworth filter was studied in the quantification of regional cerebral blood flow (rCBF) by N-isopropyl-P-[123I]-iodoamphetamine (123I-IMP) auto-radiography (ARG) to determine the adequate cutoff value by comparison with XeCT/CBF. The single photon emission computed tomography (SPECT) machine was Toshiba 3-detector GCA-9300A/PI equipped with a low energy high resolution fanbeam collimator and data processor GMS-5500A/PI, on which the butterworth filter was loaded. SPECT data acquisition was performed 18-48 min after 123I-IMP injection, and the data and blood radioactivity at 10 min measured by Aloka auto-well counter ARC-300 were used for calculating rCBF (ARG/CBF) values. The CCP-II phantom for the cross calibration factor (CCF) was purchased from Sangyo Kagaku Co., Ltd. and was filled with 123I-IMP (10 kBq/mL). The CT machine was Toshiba X-vigor, and CT with Xenon gas (XeCT) was done with the products of Anzai Sogyo aspirator AZ-725 and data processor AZ-7000. XeCT data acquisition was performed by 4 min aspiration/4 min washout of the gas (Xe 30%, O2 70%) and XeCT/CBF values were calculated with the processor AZ-7000. Data were selected from 80 patients (M 46, average age 62.1 y) with chronic diseases of cerebral blood vessels, in whom ARG/CBF and XeCT/CBF tests had been conducted within a week. Examined were the relationships between CF (0.523-0.930 cycles/cm) vs CCF; CF vs ARG/CBF, where rCBF was defined to be at regions of the middle cerebral artery, thalamus and cerebral ventricle; ARG/CBF vs XeCT/CBF at CF of 0.581-0.930, where the correlation coefficient (r) and slope were evaluated for decision of the optimal CF value. Under conditions employed, CBF values varied with the CF and its optimal value was found to be 0.814 cycles/cm with a best fitted slope. (T.T.)

  20. Rapid fabrication of aluminum nitride with high thermal conductivity by millimeter-wave heating method

    International Nuclear Information System (INIS)

    Full text: Aluminum nitride has been interested for the usage of heat-sink substrate in the semiconductor device on account of its high thermal conductivity. But aluminum nitride is not so easily sintered similarly as other nitrides. Polycrystalline bulk aluminum nitride is generally sintered by adding some sintering aids. However, high sintering temperature around 2000 deg C is still required for attaining full densification with the conventional sintering method. In the present study, we show millimeter-wave heating method is the rapid and low temperature process for producing aluminum nitride with high thermal conductivity. Importance in the selection of sintering aid is indicated in the millimeter-wave sintering of aluminum nitride. The relation between thermal conductivity and microstructure is also discussed. AlN powder with the average size of 1μm (Mitsui Kagaku, MAN-2) was used as the starting raw material and Y2O3 or Yb2O3 (Shin-etsu Kagaku, average size; 0.25μm and 1.2μm, UU- and RU-grades, respectively) were used as sintering aids, respectively. After mixing AlN powder and sintering aid at a desired content, the mixed powder with 1-propanol and dispersant was milled for 20 hr with alumina balls in an alumina pot. The milled powder was shaped to the circular disk with 40 mm in diameter and 4-5 mm in thickness by slip-casting method. After drying enough, the slip-casted body was calcined at 600 deg C for 1 h in nitrogen atmosphere. The calcined body was sintered in nitrogen without hydrogen or with several % hydrogen by using millimeter-wave heating method. Millimeter-wave heating was performed in a multi-mode applicator (Fuji Denpa Kogyo, FGS-10-28) combined with a high power 28 GHz gyrotron generator. Density of sintered body was calculated from measured size and weight, and when the relative density was over 90%, the precise density was measured by Archimedean method using oleic acid as immersion liquid. Thermal conductivity of sintered body was