WorldWideScience

Sample records for chloride efecto inhibidor

  1. Ensayos de laboratorio sobre el efecto inhibidor de los NO2- sobre la corrosión de las armaduras

    Directory of Open Access Journals (Sweden)

    Alonso, C.

    1984-09-01

    Full Text Available We present the summary of several years of research about the inhibitor effect of NO2- on the corrosion of reinforcements. We have studied their inhibitor effect using galvanostatic and potentiodynamic polarization curves and we have measured the corrosion rates using the Polarization Resistance method (linear polarization. We have verified by this last technique, Rp, that the NO2- in concrete, if they are used in sufficient proportion, are a complete inhibitor when the Cl are added during the mixing (e.g. mixing whith sea water, CaCl2 as an accelerator in inbitor. Inssufficient amounts of NO2- have never provoked more corrosion in our experiments in concrete. The presence of NO2- always have produced a beneficial effect. The NO2- are also beneficial in carbonated concrete, suppressing or, at least, reducing the attacked area and the corrosion rate of the reinforcements.Se presenta el resumen de varios años de investigación sobre el efecto inhibidor de los NO2- en la corrosión de las armaduras. Se ha estudiado su efecto inhibidor mediante el trazado de curvas potenciodinámicas y galvanostáticas y se han medido velocidades de corrosión instantánea usando el método de Resistencia de Polarización. Se ha podido comprobar mediante esta última técnica que, cuando hay Cl presentes desde el momento del amasado, los NO2- inhiben completamente el ataque si se añaden en cantidad suficiente. Cantidades insuficientes de NO2- nunca han provocado mayores ataques en nuestros ensayos, sino que siempre han reducido el área corroída o la intensidad del ataque. Los NO2- son también efectivos en hormigón carbonatado donde, al menos, siempre reducen el ataque cuando no lo inhiben por completo.

  2. EFECTO DE LOS BRASINOESTEROIDES Y UN INHIBIDOR DE SU BIOSÍNTESIS EN PLÁNTULAS DE DOS VARIEDADES DE TOMATE SOMETIDAS A ESTRÉS SALINO

    Directory of Open Access Journals (Sweden)

    Yanelis Reyes Guerrero

    2014-01-01

    Full Text Available Los brasinoesteroides (BRs están considerados actualmente la sexta clase de hormonas vegetales. En los últimos años, varios autores han estudiado la protección que los BR le confieren a las plantas ante determinados tipos de estrés tanto bióticos como abióticos. En este trabajo se evaluó la germinación, el crecimiento inicial, los niveles de prolina y malondialdehído (MDA y la actividad peroxidasa de dos variedades de tomate (INCA 9(1 y Amalia sometidas a estrés salino y tratadas con un brasinoesteroide natural (24-epibrasinólida, EBL, un análogo espirostánico de brasinoesteroide (Biobras-16 y un inhibidor de la biosíntesis de los brasinoesteroides (Brz2001. Para ello semillas de estas dos variedades se trataron durante cuatro horas con EBL (0,1μmol.L -1 , Biobras-16 (0,1μmol.L -1 , Brz2001 (10 μmol.L -1 , y la combinación de los brasinoesteroides con el inhibidor. Posteriormente se colocaron, en placas Petri durante siete días, en presencia o no NaCl (75 mmol.L -1 . Se evidenció que ambos brasinoesteroides lograron recuperar la germinación de las semillas estresadas con NaCl, mientras que el Brz2001 con NaCl inhibió la germinación. En el caso del crecimiento se evidenció un efecto protector de la EBL en la longitud del tallo y la masa seca de las plántulas estresadas, mientras que en la longitud de la raíz tuvo un efecto negativo. Los niveles de prolina y la actividad peroxidasa aumentaron en todos los tratamientos excepto el control, mientras que los niveles de MDA se mantuvieron inalterables en todos los tratamientos. En el caso de la prolina la EBL logró reducir estos niveles en las plántulas estresadas.

  3. Efecto de dos inhibidores de la nitrificación sobre la concentración de nitratos en pasto elefante (Pennisetum purpureum Schum.)

    OpenAIRE

    Sánchez G. Hugo; Muñoz Q. César A.; Grajales L. Henry A.

    1986-01-01

    Se compararon dos inhibidores de la nitrificación (Sulfatiazol, N- Serve) y las tendencias de la conversión de amonio a nitrato en el suelo y la concentración de este ión en el pasto según la fuente (Urea, Nitrón 26) y las dosis de nitrógeno (100, 200 kg/ha). Las concentraciones de nitratos en los suelos y en el tejido vegetal tendieron a incrementarse a medida que aumentaban los niveles de fertilización. La efectividad de los inhibidores se encuentra determinada por los niveles de fertilizac...

  4. Efecto de dos inhibidores de la nitrificación sobre la concentración de nitratos en pasto elefante (Pennisetum purpureum Schum.

    Directory of Open Access Journals (Sweden)

    Sánchez G. Hugo

    1986-09-01

    Full Text Available Se compararon dos inhibidores de la nitrificación (Sulfatiazol, N- Serve y las tendencias de la conversión de amonio a nitrato en el suelo y la concentración de este ión en el pasto según la fuente (Urea, Nitrón 26 y las dosis de nitrógeno (100, 200 kg/ha. Las concentraciones de nitratos en los suelos y en el tejido vegetal tendieron a incrementarse a medida que aumentaban los niveles de fertilización. La efectividad de los inhibidores se encuentra determinada por los niveles de fertilización y, en algunos casos, por las condiciones medio ambientales presentes.It was compared the grade of inhibition of two inhibitors products of the nitrification (Sulfatiazol, N - Serve and the tendencies on the conversion of ammonium into nitrate in the ground and the concentration of this ion on Pennisetum purpureum Schum. Depending on the source (urea, Nitrón 26 and the quantity of nitrogen (100, 200 kq/ha. The concentrations of nitrates on the grounds and the vegetal tissue stretched to intensity at the same time as were increase the levels of nitrogenous. The effectiveness of the inhibitors is determined for the employed levels and in some cases for the present environment conditions.

  5. Effect of Ethylene Inhibitors on Quality Attributes of Apricot cv. Modesto and Patterson during Storage Efecto de los Inhibidores de Etileno sobre Atributos de Calidad de Damascos, Variedades Modesto y Patterson durante Almacenamiento

    Directory of Open Access Journals (Sweden)

    Héctor Valdés

    2009-06-01

    tras 20 y 30 días de almacenamiento a 0 ºC con su respectiva evaluación tras 3 a 4 días a 20 °C. En ambas variedades, los inhibidores de etileno aplicados tienen efecto en disminuir la tasa de producción de etileno respecto al testigo, especialmente para Patterson. También se observó un efecto en la firmeza y retención de color de los frutos, presentando los tratamientos con inhibidores de etileno valores superiores respecto al testigo, por lo que estos parámetros serían dependientes de la producción de etileno. Para contenido de sólidos solubles y acidez titulable, no se obtuvieron resultados que puedan establecer diferencias entre frutos tratados y no tratados, por lo tanto se consideran etileno independientes. Los volátiles que presentaron una dependencia de la producción de etileno fueron los pertenecientes a los grupos de ésteres y aldehídos, no siendo el caso de los alcoholes y terpenos que no presentaron variaciones, lo que sugiere que el etileno no estaría involucrado en su síntesis.

  6. Effect of Nitrogen Inhibitors on Nitrous Oxide Emissions and Pasture Growth After an Autumn Application in Volcanic Soil Efecto de Inhibidores de Nitrógeno en las Emisiones de Óxido Nitroso y Crecimiento de la Pradera después de la Aplicación Otoñal en un Suelo Volcánico

    Directory of Open Access Journals (Sweden)

    Erika Vistoso

    2012-03-01

    Full Text Available A range of technologies is available to reduce greenhouse gas emissions from agricultural systems. Among these, applying N transformation inhibitors is promising in reducing nitrous oxide (N2O emissions in both arable and pastoral soils. A randomized complete block design with six replicates was used to quantify the effect of urease (UI and nitrification (NI inhibitors on N2O emissions and pasture production from permanent pasture in an Andisol after autumn-applied urea. The N2O emissions were measured periodically for 8 wk with PVC stationary chambers. Mineral N, DM yield, N concentration, and N uptake were analyzed. Our results show that adding fertilizer (40 kg N ha-1 significantly increased N2O emissions by 281% over the control treatment (P Una gama de tecnologías están disponibles para reducir las emisiones de gases de efecto invernadero desde sistemas agrícolas. Entre éstas, la aplicación de inhibidores de transformación del N es considerada prometedora para reducir emisiones de oxido nitroso (N2O en suelos de cultivo y praderas. Un diseño de bloques completos al azar con seis repeticiones se utilizó para cuantificar el efecto de inhibidores de ureasa (UI y nitrificación (NI sobre emisiones de N2O y producción de pradera permanente sobre un Andisol después de la aplicación otoñal de urea. Las emisiones de N2O se midieron periódicamente durante 8 semanas en cámara estacionaria de PVC. Se analizaron N mineral, rendimiento de MS, concentración de N, y absorción de N. Los resultados muestran que la aplicación de fertilizante (40 kg N ha-1 aumentó significativamente las emisiones de N2O en 281% sobre el tratamiento control (P < 0,05 y generó 10-29% de reducción de emisiones. Ambos inhibidores redujeron la producción de N-nitrato en el Andisol serie Osorno por detener la hidrólisis de urea o el proceso de nitrificación. Se midieron aumentos en producción (8-13%, concentración N (7-9% y absorción N (46-56% con la adici

  7. Análisis de los efectos de las interrupciones en el tratamiento con inhibidores de Tirosina Quinasa en cuanto a logro y mantenimiento de la respuesta molecular en pacientes con Leucemia Mieloide Crónica

    OpenAIRE

    Martínez Cordero, Humberto

    2015-01-01

    Introducción: La Leucemia Mieloide Crónica (LMC) es una enfermedad que puede mostrar un comportamiento benigno durando en fase crónica una gran cantidad de tiempo, gracias al tratamiento con inhibidores de tirosina quinasa (ITK). Para alcanzar los resultados mostrados en los estudios se requiere que se cumplan unas condiciones rigurosas de adherencia con mínimas interrupciones del tratamiento. Objetivos: Demostrar que las interrupciones del tratamiento con ITK en los paci...

  8. Inhibidores de glucosidasas en alimentos

    OpenAIRE

    Garrido de Castro, Leticia

    2014-01-01

    Los inhibidores de glucosidasas son elementos clave para la regulación de los niveles plasmáticos post-prandiales de glucosa. Esta regulación permite la prevención y regulación de diferentes patologías siendo la principal la diabetes mellitus (DM), pero también el exceso de peso y el cáncer colorrectal, e indirectamente las patologías cardiovasculares. Hoy en día se pueden encontrar inhibidores de glucosidasas obtenidos de forma sintética, pero no se debe olvidar que también pueden encontr...

  9. Inhibidores de proteasas en leguminosas

    OpenAIRE

    García Esteban, Cristina

    2014-01-01

    Desde hace varios años se ha hecho hincapié en el estudio de los inhibidores de proteasas de las legumbres, en especial de la soja, y sus posibles funciones biológicas sobre el organismo humano. Las proteasas son importantes para digerir las proteínas, degradándolas a aminoácidos para su posterior absorción en intestino. El procesado por calor de las legumbres es imprescindible ya que al contener inhibidores de proteasas, los cuales no permiten una digestión adecuada de las proteasas, dificul...

  10. Los inhibidores de corrosión

    Directory of Open Access Journals (Sweden)

    Godínez, L. A.

    2003-04-01

    Full Text Available In this paper, we briefly describe the characteristics, cost and electrochemical nature of the corrosion phenomena as well as some of the technologies that are currently employed to minimize its effect. The main subject of the paper however, deals with the description, classification and mechanism of protection of the so-called corrosion inhibitors. Examples of the use of these substances in different aggressive environments are also presented as means to show that these compounds, or their combination, can in fact be used as excellent and relatively cheap technologies to control the corrosion of some metals. In the last part of the paper, the most commonly used techniques to evaluate the efficiency and performance of corrosion inhibitors are presented as well as some criteria to make a careful and proper selection of a corrosion inhibitor technology in a given situation.

    En este trabajo, se describe el fenómeno de la degradación por corrosión electroquímica de los metales, sus efectos y costos, así como algunas de las técnicas empleadas para minimizar su impacto. Se hace énfasis en la descripción y mecanismo de acción de los inhibidores de corrosión y, con base en lo anterior, se plantea que el uso de estas substancias puede constituir un enfoque efectivo y relativamente barato para controlar la corrosión de algunos metales. En la última parte del artículo, se discuten brevemente algunas de las técnicas comúnmente empleadas para evaluar la actuación de los inhibidores de corrosión y algunos criterios generales para hacer una selección apropiada de los mismos.

  11. Inhibidores de escaso impacto medioambiental. Sistemas basados en tierras raras

    Directory of Open Access Journals (Sweden)

    Aballe, A.

    1997-12-01

    Full Text Available Lanthanum, Cerium and Samarium chlorides have been investigated as uniform and pitting corrosion inhibitors of AISI 434 and AISI 304 stainless steels and AA 5083 Al-Mg alloy in 3.5 % NaCl aerated aqueous solutions. Their inhibitor power was evaluated by using electrochemical techniques such as Linear and Cyclic Polarisation. In each case, the highest protection degree was found in the solution dopped with 500 ppm of CeCl3. Similar results were obtained for additions of 500 ppm of LaCl3. Scanning Electron Microscopy and Energy Dispersive Spectroscopy allowed us to confirm the cathodic nature of the inhibition process.

    Se estudia el comportamiento de los cloruros de lantano, cerio y samario como inhibidores de los procesos de corrosión uniforme y por picaduras de los aceros inoxidables AISI 434 y AISI 304 y de la aleación de aluminio AA 5083 en disoluciones aireadas de NaCl al 3,5 %. Utilizando técnicas electroquímicas como polarización lineal y cíclica, se ha podido evaluar el poder inhibidor de estas sustancias. El mejor comportamiento inhibidor se ha obtenido para una concentración de 500 ppm de CeCl3, si bien para los aceros se obtienen resultados del mismo orden para 500 ppm de LaCl3. Con la ayuda de microscopía electrónica de barrido y espectroscopia de dispersión de energía se ha podido confirmar el carácter catódico del mecanismo de inhibición que tiene lugar en el proceso.

  12. The effect of prostaglandin synthase inhibitor, aspirin on the rat intestinal membrane structure and function El efecto del inhibidor de la sintasa de prostaglandina, aspirina, sobre la estructura y función de la membrana intestinal de la rata

    Directory of Open Access Journals (Sweden)

    G. Kaur

    2010-04-01

    and biological functions of the intestinal membrane.Se encontró que la aspirina a una dosis de 50 mg/kg de peso corporal disminuye la actividad de las enzimas asociadas a la membrana con borde en cepillo (MBC del intestino de la rata como la sucrasa, lactasa, maltasa y fosfata alcalina. El tratamiento con aspirina también produjo una disminución de la microviscosidad en la membrana nativa así como en la membrana tratada con alcohol bencílico, lo que podría deberse a la lesión de peroxidación lipídica de la membrana. La correlación física de la lesión oxidativa de la membrana fue evidente como mostró el estudio Fourier Transformation Infra Red (FTIR de la membrana tratada con aspirina, que incluía un aumento en la proporción de la conformación levo a trans, un cambio en las frecuencias de estiramiento metileno C-H asimétrico y simétrico, el estiramiento de los dobles enlaces C = O, la curvatura NH, la curvatura anti-simétrica (N-CH3, el estiramiento C-N y el estiramiento anti-simétrico CNC, mientras que no hubo cambios en el movimiento y retorcimiento CH2 ni en la curvatura NH del enlace amida I y II. El tratamiento con aspirina también produjo una alteración en el transporte de glucosa e histidina, como se evidenció por una disminución del valor de la Vmax mientras que la Km aparente permaneció inalterada en los animales control y tratados con aspirina, lo que confirma que no hubo cambios en la constante de afinidad por el sustrato de las proteínas transportadoras de membrana para la glucosa y el aminoácido básico, si bien la tasa de transporte disminuyó considerablemente. Se apreció un descenso en la energía de activación del transporte de glucosa e histidina cuando se estudiaron a temperaturas distintas, pero no hubo cambios en la temperatura de la fase de transición de la MBC con el tratamiento con aspirina, lo que implica que quizás la fase de transición termotrópica en la membrana pudiera tener un efecto relativamente peque

  13. La enfermedad de Alzheimer y los inhibidores de la colinesterasa

    Directory of Open Access Journals (Sweden)

    Carlos Luis Alpízar-Quesada

    2003-06-01

    Full Text Available La enfermedad de alzheimer (EA, es muy frecuente en la vejez donde se pierden, en forma lenta y progresiva, capacidades cognoscitivas y motoras. Esta enfermedad ha ido en aumento conforme se incrementa la expectativa de vida de la población. En los últimos años, descubrir un tratamiento efectivo para esta enfermedad ha sido un verdadero reto científico. A pesar de que su patología fue descrita hace algunos años, no hubo tratamiento disponible hasta hace poco tiempo. Desde principios de los noventa se inició el estudio de los inhibidores de la colinesterasa. Se presentó así, por primera vez, una probable solución sintomática a esta enfermedad. En 1993 salió al mercado la tacrina, primer medicamento de esta clase. En la actualidad hay más variedad de tratamientos, algunos han dado excelentes resultados, como es el caso de la rivastigmina. A pesar de que todos pertenecen a la misma clase farmacológica, hay grandes diferencias en cuanto a su especificidad, su selectividad y efectos secundarios. A continuación se describen y analizan los tratamientos disponibles para esta enfermedad.Alzheimer’s disease has a higher incidence in elderly than in middle-aged persons. As the expectancy of life increases, this disease becomes more frequent. It is characterized by a progressive loss of cognitive and motor abilities. Finding an adequate treatment has become a scientific challenge in recent years, because even though the physiopathology of this disease was described many years ago, no treatment was available for a long time. The studies on colinesterase inhibitors began since the early 90's representing these drugs a first possible cure. In 1993, tacrine, the first colinesterase inhibitor, was approved for use in patients with Alzheimer ’s disease. Nowadays we have multiple drugs of this type, some with excellent results such as rivastigmine. Even though they are of the same pharmacological class, these drugs are very different in their

  14. Inhibidores de transferencia de colorante durante el lavado desde tejidos de algodón teñidos con colorantes directos

    OpenAIRE

    Carrión Fité, Francisco Javier; Espinosa, Eva

    2003-01-01

    El objetivo de este trabajo fue el estudio del efecto de tres polímeros de polivilvinilpirrolidona (PVP), de diferente peso molecular y un copolímero de vinilpirrolidona/vinilmidazol (PVP/VI) para su aplicación como DTI (inhibidores de transferencia de colorante). Tales productos fueron utilizados en varias formulaciones de detergente en el lavado repetido de tejido de algodón que fue teñido con diferentes colorantes directos y se aplicó un tratamiento posterior con objeto de mejorar la solid...

  15. Effect of etoricoxib, a cyclooxygenase-2 selective inhibitor on aberrant crypt formation and apoptosis in 1,2 dimethyl hydrazine induced colon carcinogenesis in rat model Efecto del etoricoxib, un inhibidor selectivo de la ciclooxigenasa-2, sobre la formación de criptas aberrantes y la apoptosis en un modelo murino de carcinogénesis de colon inducidad por 1,2-dimetilhidracina

    Directory of Open Access Journals (Sweden)

    P. Sharma

    2010-02-01

    reverted back with the etoricoxib treatment. The cytoplasmic expression of COX-2 protein was studied in paraffin sections of the colon by immunohistochemistry with COX-2 specific antibody which showed a very high presence of this inducible enzyme with the DMH group while in all other groups of animals it was not visible or weekly expressed. The anti-inflammatory effect of the drug, etoricoxib was also validated by a carrageenan-induced inflammation in rat model which showed an extremely high anti-inflammatory response within the dose range used in the present study. Also the growth profile of all the animals remained the same throughout the six week period of the investigation as there was no change in the body weight. It appears that apoptosis remains the dominant anti-proliferative end effect of this drug, mediated by an inhibition of the proinflammatory COX-2 isoform although further molecular probings are needed to arrive at a conclusive agreement in favor of the chemoprotective use of such drugs in colon cancers.El Etoricoxib, un inhibidor selectivo de la ciclooxigenasa-2 (COX-2 de segunda generación, se ha estudiado por la respuesta quimiopreventiva a su dosis terapéutica antiinflamatoria en un modelo murino de carcinogénesis colónica inducida por 1,2-dimetilhidracina (DMH. Se dividió en cuatro grupos a ratas de la cepa Sprague-Dawley de ocho a diez semanas de vida. El grupo 1 sirvió de control y recibió el vehículo de los fármacos, y a los grupos 2 y 3 se les administró DMH recién preparada en EDTA-salino al 1 mM (pH 7,0 (30 mg/kg peso corporal/semana, subcutáneamente. El grupo 3 también recibió a diario tratamiento con etoricoxib (0,6 mg/kg peso corporal, por vía oral, mientras que el grupo 4 solamente recibió la misma cantidad de etoricoxib, preparado en 0,5% carboximetil celulosa. Se sacrificó a los animales al final de la sexta semana, se registró el peso corporal y se realizaron estudios macroscópicos e histopatológicos del colon. El n

  16. Derivados Sp2 imnoazúcar como inhibidores de las a-glicosidasas

    OpenAIRE

    García Fernández, José Manuel; Sánchez, Elena; Ortiz-Mellet, Carmen; Rísquez-Cuadro, Rocio

    2010-01-01

    Derivados glicosilados de fórmula 1, donde los significados para los distintos sustituyentes son los indicados en la descripción. Estos compuestos son útiles como inhibidores de las a-glicosidasas.

  17. Efecto de fertilizantes orgánicos y minerales y dos sistemas de riego en las emisiones de Gases de Efecto Invernadero en un cultivo de maíz

    OpenAIRE

    Cangani, Max T.; Guardia Vázquez, Guillermo; Sanz Cobeña, Alberto; Andreu, Gemma; Téllez Del Río, Ángela; García Marco, Sonia; Vallejo Garcia, Antonio

    2015-01-01

    La aplicación de fertilizantes orgánicos junto con inhibidores de la nitrificación, y su interacción con sistemas de riego localizado pueden conducir a un incremento en la eficiencia en el uso de nitrógeno (N), reduciendo las pérdidas por volatilización de NH3 y las emisiones de gases de efecto invernadero (GEI).

  18. Reducción de sodio en lomo y jamón curados. Efecto sobre la proteolisis y las características sensoriales

    OpenAIRE

    ARMENTEROS CUESTA, MÓNICA

    2010-01-01

    [Español]: En esta tesis se abordó en primer lugar el estudio “in vitro” del efecto del NaCl, KCl, MgCl2 y CaCl2 sobre la actividad de las enzimas proteolíticas musculares (catepsinas, dipeptidilpeptidasas y aminopeptidasas). Se comprobó que el KCl no ejercía ningún efecto significativamente diferente al del NaCl sobre la actividad de dichas enzimas, mientras que se necesitaron concentraciones mucho más bajas de sales divalentes (CaCl2 y MgCl2) para conseguir el mismo efecto inhibidor. ...

  19. Inhibidores de dipeptidil dipeptidasa-IV: de la teoría a la práctica

    Directory of Open Access Journals (Sweden)

    Yessica Agudelo-Zapata

    2015-04-01

    Full Text Available Esta revisión de los inhibidores de dipeptidil peptidasa-IV busca motivar el uso racional de tal grupo farmacológico en la práctica diaria. Este grupo es una nueva opción terapéutica en monoterapia o terapia combinada para el tratamiento de los pacientes con diabetes mellitus tipo 2. En Colombia, se encuentran disponibles: sitagliptina, vildagliptina, saxagliptina y linagliptina. Si bien todas las gliptinas tienen el mismo mecanismo de acción-aumentan la vida media del péptido similar al glucagón-, esta revisión presenta las diferencias entre sus propiedades farmacológicas, eventos adversos y perfil de seguridad. Estos medicamentos son de segunda o tercera línea para el tratamiento oral de los pacientes con diabetes mellitus tipo 2, o primera línea en los pacientes intolerantes a la metformina. Además, algunas de las ventajas que tienen son que: generan menor riesgo de hipoglucemia, tienen efecto neutro sobre el peso, son seguros en adultos mayores, disminuyen la variabilidad de la glucemia y, adicionalmente, se pueden utilizar en la enfermedad renal crónica avanzada, con o sin terapia de reemplazo renal, y en la insuficiencia hepática.

  20. Incretinas, Incretinomiméticos, Inhibidores de DPP IV: 1er parte Incretins, Incretinmimetics, Inhibitors

    Directory of Open Access Journals (Sweden)

    Claudia Bayón

    2010-04-01

    Full Text Available En los últimos años se reconoce un nuevo mecanismo involucrado en la fisiopatología de la Diabetes Mellitus tipo 2: el déficit de producción y/o acción de las incretinas. Las incretinas son enterohormonas que estimulan la secreción de insulina en respuesta a la ingesta de nutrientes. Glucagon like péptido-1 (GLP1 y Polipéptido insulinotrópico glucosa dependiente (GIP son las principales incretinas descubiertas hasta hoy. Ambas presentan también efecto trófico sobre las células beta de los islotes pancreáticos. GLP-1 presenta otras acciones como son la inhibición de la secreción de glucagón, enlentecimiento del vaciamiento gástrico e inhibición del apetito. Ambas incretinas son rápidamente clivadas por la enzima dipeptidil peptidasa 4 (DPP-4. Nuevas drogas como los incretinomiméticos, análogos y los inhibidores de DPP-4 se presentan como una terapéutica prometedora para los pacientes con diabetes tipo 2.Two main patophysiological mechanisms are currently involved in Type 2 Diabetes (T2DM, insulin resistance and impairment of beta cell function. However in the last years a new mechanism was reported: a significant decrease in incretins production and or action. Incretins are gut hormones whose main action is stimulating insulin secretion in response to nutrients. The more known incretins are glucagon like peptide-1 (GLP-1 and Gastric insulinothropic peptide (GIP. GLP-1 and GIP not only increase insulin secretion, nor decrease glucagon secretion, slow gastric emptying and reduce apetite generating weight lose. Both incretins are rapidly clived by the enzyme dipeptidil peptidase 4 (DPP4. In order to emulate incretins action, several drugs where developed: agonists of GLP-1 receptors, GLP-1 mimetics, and inhibitors of the DPP4. All of them seems to became a very promise tool for the treatment of T2DM.

  1. Inhibidor de la enzima uracilo ADN glicosilasa y usos del mismo

    OpenAIRE

    Serrano-Heras, Gemma; Bravo García, Alicia; Salas, Margarita

    2005-01-01

    Inhibidor de la enzima uracilo adn glicosilasa y usos del mismo Esta invención se refiere a una proteína que inhibe la enzima uracilo ADN glicosilasa (UDG) vírica, para su uso como un agente terapéutico, en particular como un agente antiví

  2. Efectos del óxido nítrico inhalado en un modelo experimental de ventilación unipulmonar

    OpenAIRE

    López Gutiérrez, Ana María

    2005-01-01

    [spa] Introducción Durante la ventilación unipulmonar puede aparecer hipoxemia severa. La modulación farmacológica del flujo pulmonar es una atractiva estrategia de manejo. El óxido nítrico inhalado (iNO) es un vasodilatador pulmonar selectivo de las zonas ventiladas que produce redistribución del flujo pulmonar hacia éstas mejorando la relación ventilación/perfusión y el intercambio de gases. Estos efectos pueden verse potenciados por los inhibidores de la síntesis de las prostaglandinas y d...

  3. EFECTO DEL ESTRÉS HÍDRICO Y SALINO SOBRE LA GERMINACIÓN DE Atriplex nummularia (CHENOPODIACEAE) Effect of Water and Saline Stress on Germination of Atriplex nummularia (Chenopodiaceae)

    OpenAIRE

    MÓNICA B. RUIZ; CARLOS A. PARERA

    2013-01-01

    Los suelos salinos, característicos de zonas áridas, pueden afectar la germinación de las especies por presentar bajos potenciales hídricos o por toxicidad iónica. En este trabajo se determinó el efecto del estrés hídrico y salino sobre la germinación de Atriplex nummularia, una alternativa forrajera para zonas áridas. Las semillas fueron escarificadas para minimizar el efecto inhibidor de las brácteas y germinadas a 23 ºC sobre papel de germinación en soluciones con diferente potencial hídri...

  4. Inhibidores de la MEK 1/2 para el tratamiento de la fibrosis peritoneal

    OpenAIRE

    Strippoli, Raffaele; Pozo Barriuso, Miguel Ángel del; López Cabrera, Manuel

    2008-01-01

    Inhibidores de la MEK 1/2 para el tratamiento de la fibrosis peritoneal. Fármacos útiles en la prevención y tratamiento de la fibrosis de la membrana peritoneal (opacificación peritoneal, síndrome del peritoneo bronceado, fibrosis mural y síndrome de peritonitis esclerosante) que se produce como consecuencia de una diálisis peritoneal a largo plazo, método de selección de estos fármacos, y método para la recolección de datos útiles en el diagnóstico de dicha enferme...

  5. Farmacocinética de los inhibidores de la calcineurina en trasplante pulmonar de adultos

    OpenAIRE

    Méndez Garrido, Alejandra

    2015-01-01

    Los inhibidores de la calcineurina son los fármacos fundamentales para el tratamiento inmunosupresor del trasplante pulmonar (TP). El manejo de estos fármacos se basa en la monitorización farmacocinética de los mismos, generalmente mediante estrategias de muestreo limitado. El impacto que tienen las variaciones farmacocinéticas en los resultados y cuál es la bioequivalencia entre distintas formas farmacéuticas de algunos de ellos son las preguntas de la presente tesis doctoral. Pacientes y...

  6. Betalactámicos con inhibidores de betalactamasas: Amoxicilina-sulbactam Betalactam antibiotics combined with bectalactamases inhibitors: Amoxicillin-sulbactam

    OpenAIRE

    Laura Barcelona; Marcelo Marin; Daniel Stamboulian

    2008-01-01

    La producción de betalactamasas constituye uno de los principales mecanismos de resistencia bacteriana a los antibióticos betalactámicos. La utilización de inhibidores de betalactamasas en combinación con antibióticos betalactámicos permite la inactivación de determinadas betalactamasas producidas por gérmenes Gram positivos, Gram negativos, anaerobios, y aun por micobacterias. Los inhibidores de betalactamasas representan una alternativa terapéutica mejorada respecto del resto de los betalac...

  7. Diseño, selección y síntesis de nuevos inhibidores de entrada del VIH

    OpenAIRE

    Pettersson Salom, Sofia Henriette

    2009-01-01

    La sida és una malaltia causada pel VIH, que ataca a les cèl·lules del sistema immunitari. Actualment s'estima que viuen uns 33 milions de persones infectades per aquest virus. La teràpia antiretroviral actual consisteix en combinacions de dues famílies de compostos: inhibidors de la transcriptasa inversa i inhibidors de la proteasa, ambdós dirigits a enzims específics produïts pel VIH. Una de les principals dificultats en el tractament antiretroviral és la ràpida evolució del virus, que li p...

  8. Falla cardiaca, tratamiento: diuréticos, inhibidores de la ECA y nitratos

    Directory of Open Access Journals (Sweden)

    Guillermo Trout Guardiola

    2013-10-01

    Full Text Available En los pasados 15 años grandes ensayos clínicos randomizados, controlados, han revolucionado el manejo de pacientes con falla cardiaca. Aunque es claro que algunas drogas mejoran los síntomas, otras presentan beneficios pronósticos y sintomáticos, el manejo de falla cardiaca se debe centralizar en mejorar la calidad de vida y la sobrevida. Los diuréticos y los inhibidores de la enzima convertidora de la angiotensina, combinados con medidas no farmacologicas, permanecen como el tratamiento convencional para pacientes con falla cardiaca congestiva. La digoxina tiene una posible función en algunos de estos pacientes, sin embargo, el potencial beneficio de los betabloquedores y la espironolactona en falla cardiaca crónica han aumentado su reconocimiento.

  9. Incretinas, incretinomiméticos, inhibidores de DPP IV: (2ª parte Incretins, Incretinmimetics, Inhibitors (2nd part

    Directory of Open Access Journals (Sweden)

    Claudia Bayón

    2010-09-01

    Full Text Available En los últimos años se reconoce un nuevo mecanismo involucrado en la fisiopatología de la Diabetes Mellitus tipo 2: el déficit de producción y/o acción de las incretinas. Las incretinas son enterohormonas que estimulan la secreción de insulina en respuesta a la ingesta de nutrientes. Glucagon like peptide-1 (GLP1 y Polipéptido insulinotrópico glucosa dependiente (GIP son las principales incretinas descubiertas hasta hoy. Ambas presentan también efecto trófico sobre las células beta de los islotes pancreáticos. GLP-1 presenta otras acciones como son la inhibición de la secreción de glucagón, enlentecimiento del vaciamiento gástrico e inhibición del apetito. Ambas incretinas son rápidamente clivadas por la enzima dipeptidil peptidasa 4 (DPP-4. Nuevas drogas como los incretinomiméticos, análogos y los inhibidores de DPP-4 se presentan como una terapéutica prometedora para los pacientes con diabetes tipo 2. Conflicto de intereses: Dr. León Litwak - Miembro del Board Latinoamericano de Eli Lilly y Sanofi Aventis - Miembro del Board Nacional de los laboratorios Novo Nordisk, Novartis, GlaxoSmithKline, Sanofi Aventis, Boheringer Ingelheim, Bristol Myers, Astra Zeneca - Investigador principal de protocolos pertenecientes a Eli Lilly, Novo Nordisk, Novartis, GlaxoSmithKline, Takeda, PPDF, Pfizer, Merck Sharp and Dôhme, Amger, Roche, Minimed, Quintiles - Conferencista de los laboratorios mencionados.Two main pathophysiological mechanisms are currently involved in Type 2 Diabetes (T2DM, insulin resistance and impairment of beta cell function. However, in recent years a new mechanism was reported: a significant decrease in incretins production and/or action. Incretins are gastrointestinal hormones whose main action is stimulating insulin secretion in response to nutrients. The best known incretins are glucagon like peptide-1 (GLP-1 and Gastric insulinotropic peptide (GIP. GLP-1 and GIP not only increase insulin secretion, but also

  10. Mecanismo de la apoptosis inducida por el inhibidor de quinasas sorafenib en células de mieloma humano

    OpenAIRE

    Ramírez Labrada, Ariel Gaspar; Naval Iraberri, Javier; Marzo Rubio, María Isabel

    2013-01-01

    El mieloma múltiple (MM) es la segunda neoplasia hematológica más frecuente, después del linfoma no Hodgkin y constituye, aproximadamente, el 10% de todas las neoplasias hematológicas, y el 1% de todos los cánceres y causa el 2% de las muertes por cáncer. El sorafenib es un inhibidor de múltiples quinasas diseñado originalmente como inhibidor de la vía de las MAPK. Debido que la actividad de ERK es esencial para la proliferación de las células de mieloma múltiple mediada por la IL-6, se anal...

  11. Péptidos derivados del GB virus C como potenciales inhibidores del virus de la inmunodeficiencia humana tipo 1

    OpenAIRE

    Galatola, Ramona

    2014-01-01

    Tesi realitzada a l'Institut de Química Avançada de Catalunya (IQAC-CSIC) En los últimos años, se han dedicado numerosos esfuerzos al desarrollo de nuevos fármacos inhibidores de la entrada del virus de la inmunodeficiencia humana tipo 1 (HIV-1) en la célula huésped. La principal ventaja de este tipo de inhibidores es que actúan como profilácticos, es decir pueden evitar la infección primaria y la integración del genoma viral en el genoma de la célula huésped. Esto implica una reducción de...

  12. Effects of chlorocholine chloride and paclobutrazol on cassava (Manihot esculenta Crantz cv. Rocha plant growth and tuberous root quality Efectos del cloruro de cloro colina y el paclobutrazol sobre el crecimiento de plantas y la calidad de raíces tuberosas de mandioca (Manihot esculenta Crantz cv. Rocha

    Directory of Open Access Journals (Sweden)

    R. Medina

    2012-06-01

    Full Text Available The effects of chlorocholine chloride (CCC and paclobutrazol (PBZ foliar application on shoot and root parameters of cassava field-grown plants were studied (0, 45 and 90 mg active ingredient per plant. CCC and PBZ reduced total plant and first branch height, aerial fresh mass and tuberous root number. PBZ delayed branching and significantly decreased tuberous root fresh mass, while CCC caused no modifications in these parameters. In addition, CCC and PBZ treatments did not modify tuberous root diameter, while PBZ reduced tuberous root length significantly. Starch content was increased by both growth regulators at the lower dose, whereas dry matter content was increased only by CCC. In conclusion, CCC suppresses excessive vegetative growth, favours quality attributes and does not alter yield, hence improving harvest index. Although PBZ at a low dose increases the starch content and harvest index, its effects on other parameters are undesirable.Se estudiaron los efectos de la aplicación foliar del cloruro de cloro colina (CCC y del paclobutrazol (PBZ sobre parámetros de crecimiento aéreo y radical de plantas de mandioca cultivadas a campo (0,45 y 90 mg de principio activo por planta. El CCC y el PBZ redujeron la altura total de las plantas y la altura de la primera ramificación, el peso fresco de los órganos aéreos y el número de raíces tuberosas por planta. El PBZ retrasó la ocurrencia de la ramificación y causó reducciones significativas del peso fresco de las raíces tuberosas, mientras que el CCC no afectó dichos parámetros. Los tratamientos con CCC y PBZ no modificaron el diámetro de las raíces tuberosas, aunque el PBZ redujo significativamente su longitud. El contenido de almidón de raíces tuberosas se incrementó por la aplicación de ambos reguladores del crecimiento en su dosis mínima; sin embargo, el contenido de materia seca de estas sólo fue aumentado por el tratamiento con CCC. En conclusión, el CCC evita el

  13. Effect of the chloride ions on the hydrolysis of praseodymium in a 2M ion force media; Efecto de los iones cloruro sobre la hidrolisis del praseodimio en medio de fuerza ionica 2M

    Energy Technology Data Exchange (ETDEWEB)

    Lopez G, H.; Jimenez R, M.; Solache R, M.; Rojas H, A. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    2004-07-01

    The constants of the product of solubility and the first of hydrolysis were determined of the Praseodymium in media 2M of NaClO{sub 4} and 2M of NaCl, to 303 K and under conditions free of CO{sub 2}. The diagram of solubility was obtained (pPr{sub (ac)} - pC{sub H}), by means of a radiochemical method and with it was established the pC{sub H} that limit the saturation and non saturation areas; that diagram allowed, also, to calculate the constant of the product of solubility. Also, it was adjusted with the polynomial of solubility equation, that it allowed to determine and to check the values of the constants of the product of solubility and the first of hydrolysis. Independently, it was determined the first constant of hydrolysis of the element, by means of potentiometric titrations whose data were treated with the computer program named SUPERQUAD and with the adjustment of the equation of the average number of bonds. It was also calculates the log constant {beta}{sub Pr,Cl} of the specie PrCI{sup 2+} starting from the hydrolysis constants obtained in the perchlorate and chloride media. (Author)

  14. EFECTO DEL ESTRÉS HÍDRICO Y SALINO SOBRE LA GERMINACIÓN DE Atriplex nummularia (CHENOPODIACEAE Effect of Water and Saline Stress on Germination of Atriplex nummularia (Chenopodiaceae

    Directory of Open Access Journals (Sweden)

    MÓNICA B. RUIZ

    2013-04-01

    Full Text Available Los suelos salinos, característicos de zonas áridas, pueden afectar la germinación de las especies por presentar bajos potenciales hídricos o por toxicidad iónica. En este trabajo se determinó el efecto del estrés hídrico y salino sobre la germinación de Atriplex nummularia, una alternativa forrajera para zonas áridas. Las semillas fueron escarificadas para minimizar el efecto inhibidor de las brácteas y germinadas a 23 ºC sobre papel de germinación en soluciones con diferente potencial hídrico (-0,5, -1,0 y -1,5 MPa de cloruro de sodio (NaCl y polietilenglicol (PEG, utilizando agua destilada como control. El porcentaje de germinación y la velocidad de germinación fueron significativamente afectados por la concentración de la solución y el soluto utilizado. A valores de potencial osmótico más negativos el porcentaje de germinación y velocidad de germinación fueron significativamente menores. En los tres potenciales hídricos ensayados la velocidad y el porcentaje de semillas germinadas en NaCl fue significativamente menor que en PEG, siendo especialmente notoria esta diferencia a -1,0 MPa. Los datos sugieren que las semillas de A. nummularia presentan sensibilidad a la presencia de los iones Na+ y Cl- que afectan el proceso de germinación.Saline soils, characteristic of arid zones, can affect the germination of the species due to low water potential or ion toxicity. The effect of water and saline stress on germination was evaluated in Atriplex nummularia a potential source of forage for arid zones. The seeds were scarified to reduce the inhibitory effect on germination and incubated in at 23 ºC on germination paper imbibed with solutions of sodium chloride (NaCl and polyethylen glycol (PEG at three water potentials: -0,5; -1,0 and -1,5 MPa. The percentage germination and germination speed were significantly affected by the concentration of the solution and the solute used. While more negative osmotic potentials, the

  15. Efecto del estrés hídrico y salino sobre la germinación de atriplex nummularia (chenopodiaceae)

    OpenAIRE

    Ruiz, Mónica Beatriz; Parera, Carlos Alberto

    2013-01-01

    Los suelos salinos, característicos de zonas áridas, pueden afectar la germinación de las especies por presentar bajos potenciales hídricos o por toxicidad iónica. En este trabajo se determinó el efecto del estrés hídrico y salino sobre la germinación de Atriplex nummularia, una alternativa forrajera para zonas áridas. Las semillas fueron escarificadas para minimizar el efecto inhibidor de las brácteas y germinadas a 23 ºC sobre papel de germinación en soluciones con diferente potencial hídri...

  16. Evaluación de un inhibidor utilizado en soluciones acidas bajo condiciones hidrodinámicas controladas

    Directory of Open Access Journals (Sweden)

    Salinas-Bravo, V. M.

    1997-06-01

    Full Text Available The cylindrical rotating electrode and electrochemical techniques were used to investigate the protection against corrosion of a commercial inhibitor used in hydrochloric acid solutions with and without additions of thiourea and ammonium bifluoride. The corrosion phenomenon was investigated under controlled hydrodynamic conditions. These were chosen to simulate those found in a pipe at different flow velocities. It was found that corrosion of mild steel in hydrochloric acid solutions with inhibitor is mainly controlled by activation, whereas in acid solutions with inhibitor added with thiourea and ammonium bifluoride it is mainly controlled by mass transfer. On the other hand, flow velocity of the acidic solutions affects negatively the efficiency of the inhibitor in the concentration range of 0.2 to 1.0 %.

    Utilizando el electrodo cilíndrico rotatorio y técnicas electroquímicas, se estudió la eficiencia de la protección contra la corrosión de un inhibidor comercial utilizado en soluciones de ácido clorhídrico con y sin adiciones de tiourea y bifluoruro de amonio. El fenómeno de la corrosión se investigó en condiciones hidrodinámicas controladas, seleccionadas para simular las que se establecen en una tubería a distintas velocidades de flujo. Se encontró que la corrosión del acero al carbono en soluciones de ácido clorhídrico con inhibidor de corrosión está controlada principalmente por activación, mientras que en soluciones acidas con inhibidor y adiciones de tiourea y bifluoruro de amonio está controlada principalmente por transferencia de masa. Por otra parte, la velocidad del flujo de las soluciones acidas afecta de -manera negativa a la eficiencia de protección del inhibidor estudiado en el intervalo de concentración de 0,2 a 1,0 %.

  17. Impacto del uso de inhibidores de la bomba de protones sobre el perfil fermentativo intestinal: Un estudio de tipo caso-control

    OpenAIRE

    Melisa Senderovky; Juan Lasa; Guillermo Dima; Daniel Peralta; Mariano Argüello; Luis Soifer

    2014-01-01

    Introducción. Los inhibidores de la bomba de protones po - drían influir en los resultados de estudios de hidrógeno en aire espirado realizados en sujetos con síndrome de intestino irritable. Esto se debería al favorecimiento de sobrecrecimien - to bacteriano intestinal. Objetivos. Comparar la prevalencia de alteraciones en el perfil fermentativo en sujetos con sín - drome de intestino irritable expuestos y no expuestos al trata - miento con inhibidores de la bomba de protones. Materiales y m...

  18. Efectos alelopáticos de Rumex Crispus L. sobre Pissum Sativum L

    Directory of Open Access Journals (Sweden)

    Moreno B. Luis Francisco

    1989-06-01

    Full Text Available

    Se investigaron los efectos alelopáticos de R. Crispus sobre P. sativum mediante 3 ensayos: el primero consistió en incorporar residuos de diferentes partes de la maleza a un cultivo de arveja: los otros dos, en aplicar extractos acuosos y etéricos, en diferentes concentraciones, a semillas de arveja puestas a germinar. El estudio se realizó bajo un diseño completamente al azar en parcelas divididas. El efecto se evaluó mediante la varianza y pruebas de Desviación Standard Media (DSM. Se halló que la maleza inhibe la germinación,  afecta el crecimiento y aspecto de la radicula e incrementa el crecimiento y acumulación de biomasa. Se concluye que la planta presenta alelopatía, mediante inhibidores presentes en las hojas. Esta investigación es de utilidad práctica en manejo de agroecosisternas. Por su carácter preliminar, plantea nuevas investigaciones que deberán hacerse para completar la información adquirida.

  19. Estudio de heparinas y heparinoide de bajo peso molecular, pentasacárido y heparina no fraccionada en un modelo de trombosis "in vitro". Efecto sobre el depósito de plaquetas y la formación de fibrina

    OpenAIRE

    Lozano Molero, Miguel

    1992-01-01

    [spa] La heparina es una familia de cadenas de glicosaminoglicanos (GAGs) formados por residuos de glucosamina y ácido urónico, cuya eficacia y seguridad en la profilaxis y tratamiento de las enfermedades trombóticas están bien establecidas.El descubrimiento de que parecía posible desdoblar el efecto inhibidor del factor Xa de la inhibición de la trombina, con las fracciones de bajo peso molecular de la heparina despertó grandes expectativas y condujo a la introducción en terapéutica de las h...

  20. Derivados de cromano y sus usos como inhibidores de la actividad de las proteínas desacoplantes

    OpenAIRE

    Rial, Eduardo; Viso, Alma; Fernández de la Pradilla, Roberto; Castellanos Santamaría, Esther

    2011-01-01

    Derivados de cromano y sus usos como inhibidores de la actividad de las proteínas desacoplantes. Compuestos derivados del cromano, que presentan la fórmula general (I), donde R1 y R2, son iguales o diferentes entre sí, y están representados por un átomo de hidrógeno (H) o un grupo alquilo (C1-C8); R3 está representado por un átomo de H, un halógeno, un grupo arilo o un grupo –COOR5; donde R5 es alquilo (C1-C4) o un alquilarilo; y R4 está representado por un átomo de hi...

  1. Betalactámicos con inhibidores de betalactamasas: Amoxicilina-sulbactam Betalactam antibiotics combined with bectalactamases inhibitors: Amoxicillin-sulbactam

    Directory of Open Access Journals (Sweden)

    Laura Barcelona

    2008-02-01

    Full Text Available La producción de betalactamasas constituye uno de los principales mecanismos de resistencia bacteriana a los antibióticos betalactámicos. La utilización de inhibidores de betalactamasas en combinación con antibióticos betalactámicos permite la inactivación de determinadas betalactamasas producidas por gérmenes Gram positivos, Gram negativos, anaerobios, y aun por micobacterias. Los inhibidores de betalactamasas representan una alternativa terapéutica mejorada respecto del resto de los betalactámicos al asegurar, en la mayoría de los casos, un mayor espectro antimicrobiano comparado con el de sus análogos. La actividad enzimática de las betalactamasas está dirigida específicamente a la hidrólisis del anillo betalactámico, con producción de un compuesto sin actividad antibacteriana. De acuerdo con su posición genómica dentro de los microorganismos, las betalactamasas pueden ser cromosómicas o plasmídicas. Actualmente existen tres inhibidores de betalactamasas localmente disponibles: ácido clavulánico, sulbactam y tazobactam. De ellos, sólo el sulbactam posee actividad antimicrobiana intrínseca sobre las proteínas ligadoras de penicilina. La experiencia clínica acumulada durante más de 20 años confirma que las combinaciones de betalactámicos-inhibidores de betalactamasas son efectivas en el tratamiento empírico inicial de infecciones respiratorias, intraabdominales, urinarias y ginecológicas, incluidas las de origen polimicrobiano. En el caso particular de amoxicilina-sulbactam, la evidencia citada indica que esta combinación es efectiva para el tratamiento de absceso periamigdalino, otitis media, sinusitis, neumonía extrahospitalaria, exacerbación aguda de enfermedad pulmonar obstructiva crónica (EPOC, infección del tracto urinario e infecciones ginecoobstétricas. Por su espectro y propiedades farmacológicas, la combinación amoxicilina-sulbactam constituye una excelente opción también para el tratamiento

  2. EFECTO DE LOS BRASINOESTEROIDES Y UN INHIBIDOR DE SU BIOSÍNTESIS EN PLÁNTULAS DE DOS VARIEDADES DE TOMATE SOMETIDAS A ESTRÉS SALINO

    OpenAIRE

    Yanelis Reyes Guerrero; Lissy Rosabal Ayan; Lisbel Martínez González; Luis M. Mazorra Morale; Miriam Núñez Vázquez

    2014-01-01

    Los brasinoesteroides (BRs) están considerados actualmente la sexta clase de hormonas vegetales. En los últimos años, varios autores han estudiado la protección que los BR le confieren a las plantas ante determinados tipos de estrés tanto bióticos como abióticos. En este trabajo se evaluó la germinación, el crecimiento inicial, los niveles de prolina y malondialdehído (MDA) y la actividad peroxidasa de dos variedades de tomate (INCA 9(1) y Amalia) sometidas a estrés salino y tratadas con un b...

  3. Aplicación terapéutica de agentes inhibidores de CD44 frente a la leucemia linfoblástica aguda (ALL) humana

    OpenAIRE

    Toribio, María Luisa; García-Peydró, Marina; Sánchez Madrid, Francisco

    2012-01-01

    [ES] La presente invención describe la aplicación terapéutica de agentes inhibidores de CD44 frente a la leucemia linfoblástica aguda (ALL) humana. En concreto, la presente invención hace referencia a un agente inhibidor de la función de CD44 para su uso en medicina, preferentemente para la prevención y/o tratamiento de la T-ALL humana, así como a una composición farmacéutica y un kit. La presente invención también hace referencia aun método de prevención y/o tratamiento de la T-ALL humana, a...

  4. Aplicación terapéutica de agentes inhibidores de CD44 frente a la leucemia linfoblástica aguda (ALL) humana

    OpenAIRE

    Toribio, María Luisa; García-Peydró, Marina; Sánchez Madrid, Francisco

    2012-01-01

    La presente invención describe la aplicación terapéutica de agentes inhibidores de CD44 frente a la leucemia linfoblástica aguda (ALL) humana. En concreto, la presente invención hace referencia a un agente inhibidor de la función de CD44 para su uso en medicina, preferentemente para la prevención y/o tratamiento de la T-ALL humana, así como a una composición farmacéutica y un kit. La presente invención también hace referencia a un método de prevención y/o tratamient...

  5. Derivados de 2-amino-3,5-dicianopiridina y 2-cloro-3,5-dicianopiridina como inhibidores de las enzinas colinesterasas y con capacidad neuroprotectora

    OpenAIRE

    Samadi, Abdelouahid; Álvarez-Pérez, Mónica; Soriano, Elena; Valderas, Carolina; García García, Antonio

    2010-01-01

    Compuestos heterocíclicos derivados de 2-amino-3,5-dicianopiridina y 2-cloro-3,5-dicianopiridina como inhibidores de las enzimas colinesterasas con capacidad neuroprotectora, y por lo tanto, con posible utilidad en el tratamiento de procesos neurodegenerativos, preferiblemente los compuestos de la presente invención se pueden utilizar para el tratamiento o la prevención de la enfermedad de Alzheimer, la enfermedad de Parkinson o la enfermedad de Huntington.

  6. Efectos colaterales del voto preferente

    Directory of Open Access Journals (Sweden)

    Luis Diego Brenes Villalobos

    2012-07-01

    Full Text Available El artículo describe la multiplicidad de potenciales efectos que la implementación del voto preferente podría acarrear en el ordenamiento jurídico y el sistema de partidos. La primera parte del análisis se dirige a caracterizar y definir el voto preferencial. En segunda instancia, el estudio comprenderá la revista de los efectos colaterales del voto preferente como modalidad de votación.

  7. ¿Qué debemos conocer de los inhibidores de bomba protones, para su uso en las unidades de dolor?

    Directory of Open Access Journals (Sweden)

    J. A. García-García

    2007-10-01

    Full Text Available Los inhibidores de la bomba de protones (IBP son fármacos útiles para el control de la patología asociada con la acidez gástrica, patología con una alta prevalencia dentro de la población general. En las Unidades de dolor tratamos pacientes con pluripatología y polimedicados, entre ellas patologías asociadas con la acidez gástrica. Así como también utilizamos fármacos como AINES, glucocorticoides, bifosfonatos... que pueden reactivar, empeorar la patología ligada a la acidez. El conocimiento de los aspectos farmacológicos de los IBP, tanto farmacocinéticos como farmacodinámicos, es necesario y preciso para poder elegir el más adecuado para nuestros pacientes con pluripatologia y polimedicados evitando las posibles interacciones farmacológicas que podrían afectar al estado de salud de nuestros pacientes.

  8. Efecto Fotoeléctrico

    OpenAIRE

    González Marhuenda, Pedro

    2015-01-01

    Este vídeo tiene como objetivo el análisis del efecto fotoeléctrico, es decir de la emisión de electrones por un metal cuando sobre él incide luz (radiación electromagnética) de frecuencia superior a la denominada frecuencia umbral de ese metal. El efecto se presenta primero mediante un electroscopio casero, que permite observar la descarga de una placa de zinc, previamente cargada, con una lámpara de luz ultravioleta. Después, mediante un montaje experimental más elaborado, se analiza la cor...

  9. Chloride ingress prediction

    DEFF Research Database (Denmark)

    Frederiksen, Jens Mejer; Geiker, Mette Rica

    Prediction of chloride ingress into concrete is an important part of durability design of reinforced concrete structures exposed to chloride containing environment. This paper presents the state-of-the art: an analytical model which describes chloride profiles in concrete as function of depth and...... makes physical sense for the design engineer, i.e. the achieved chloride diffusion coefficients at 1 year and 100 years, D1 and D100 respectively, and the corresponding achieved chloride concentrations at the exposed concrete surface, C1 and C100. Data from field exposure supports the assumption of time...... dependent surface chloride concentrations and the diffusion coefficients. Model parameters for Portland cement concretes with and without silica fume and fly ash in marine atmospheric and submerged South Scandinavian environment are suggested in a companion paper based on 10 years field exposure data....

  10. Evolución de la fibrosis hepática en reclusos coinfectados por VIH y VHC que inician tratamiento con inhibidores de la proteasa potenciados

    OpenAIRE

    P. Saiz de la Hoya Zamácola; C. Alía Alía; Marco, A.; A. López Burgos; J. de Juan Ramírez; A. Herrero Matías; J. Portilla Sogorb

    2013-01-01

    Objetivos: Analizar la evolución de la fibrosis hepática medida por elastografía y pruebas bioquímicas en reclusos coinfectados por VIH y VHC que han iniciado tratamiento antirretroviral con lopinavir/ritonavir u otros inhibidores de la proteasa potenciados con ritonavir. Métodos: Estudio prospectivo, observacional y multicéntrico. Se comprobó durante 48 semanas la evolución de la fibrosis hepática medida mediante elastografía de transición (FibroScan) y pruebas bioquímicas en población penit...

  11. Inhibidores de α- amilasas de la broca del cafe Hypothenemus hampei en diferentes especies de vegetales α-Amylase inhibitors of the cofee berry borer Hypothenemus hampei in different plant species

    OpenAIRE

    Beatriz Elena Padilla; José Ricardo Acuña Z; Claudia S Velásquez; José David Rubio G

    2006-01-01

    La antibiosis es uno de los mecanismos de resistencia de las plantas al ataque de insectos, en el cual están involucradas proteínas de defensa como los inhibidores de α- amilasas. Estas se encuentran principalmente en especies vegetales como gramíneas y leguminosas. En Phaseolus vulgaris L. var radical se ha registrado un inhibidor de α- amilasas de la broca del café Hypothenemus hampei, con más de 80% de inhibición, el cuál también inhibe las α- amilasas de mamíferos. Siend...

  12. Chloride ingress prediction

    DEFF Research Database (Denmark)

    Frederiksen, Jens Mejer; Geiker, Mette Rica

    Prediction of chloride ingress into concrete is an important part of durability design of reinforced concrete structures exposed to chloride containing environment. This paper presents experimentally based design parameters for Portland cement concretes with and without silica fume and fly ash in...... marine atmospheric and submersed South Scandinavian environment. The design parameters are based on sequential measurements of 86 chloride profiles taken over ten years from 13 different types of concrete. The design parameters provide the input for an analytical model for chloride profiles as function...

  13. Chloride ingress prediction

    DEFF Research Database (Denmark)

    Frederiksen, Jens Mejer; Geiker, Mette Rica

    2008-01-01

    Prediction of chloride ingress into concrete is an important part of durability design of reinforced concrete structures exposed to chloride containing environment. This paper presents experimentally based design parameters for Portland cement concretes with and without silica fume and fly ash in...

  14. Ocurrencia de tóxicos naturales en frijol colorado (Phaseolus vulgaris y arveja (Pisum sativum. Efecto del tiempo de almacenamiento y los tratamientos caseros.

    Directory of Open Access Journals (Sweden)

    Bilbao Reboredo Tania

    2000-06-01

    Full Text Available Las leguminosas, consideradas como una de los principales alimentos para el hombre pueden contener diferentes sustancias conocidas como antinutrientes las cuales tienen cierto efecto en la nutrición humana y animal si no son removidos o inactivados adecuadamente. En Cuba existe muy poca información sobre cuales son los antinutrientes y en qué concentraciones se encuentran en dos de las leguminosas de importación de mayor consumo por nuestra población: el frijol común (Phaseolus vulgaris y la arveja (Pisum sativum y tampoco se han estudiado los cambios que pueden sufrir durante su almacenamiento, así como la efectividad de los tratamientos caseros. Muestras de estos granos fueron analizadas durante un año de almacenamiento comercial a una temperatura promedio de 27 °C y 79 % de humedad relativa. Se evaluó la presencia de taninos, ácido cianhídrico, ácido fítico, inhibidores de proteasas y lectinas, en los granos crudos y después de dos tratamientos: remojo y cocción y cocción directamente, en olla de presión. Todos los antinutientes disminuyeron con el tiempo de almacenamiento (p<0,05. Los tratamientos aplicados eliminaron el ácido cianhídrico, los inhibidores de tripsina y las lectinas en los dos tipos de granos, comprobándose la efectividad de la combinación remojo-cocción sobre la aplicación únicamente del tratamiento térmico, sobre el resto de los antinutrientes.

  15. Chloride ingress prediction

    DEFF Research Database (Denmark)

    Frederiksen, Jens Mejer; Geiker, Mette Rica

    2008-01-01

    makes physical sense for the design engineer, i.e. the achieved chloride diffusion coefficients at 1 year and 100 years, D1 and D100 respectively, and the corresponding achieved chloride concentrations at the exposed concrete surface, C1 and C100. Data from field exposure supports the assumption of time...... dependent surface chloride concentrations and the diffusion coefficients. Model parameters for Portland cement concretes with and without silica fume and fly ash in marine atmospheric and submerged South Scandinavian environment are suggested in a companion paper based on 10 years field exposure data....

  16. Antiinflamatórios não esteróides inibidores da ciclooxigenase-2 (COX-2: aspectos atuais Antiinflamatorios no esteróides inhibidores de la ciclooxigenasa-2 (COX-2: aspectos actuales Cycloxygenase-2 inhibitors nonsteroid anti-inflammatory drugs: current issues

    Directory of Open Access Journals (Sweden)

    Carmen Luize Kummer

    2002-07-01

    o constitutiva y COX-2 o inductiva, formuló el paradigma que las propiedades antiinflamatorias de los AINES serian mediadas a través de la inhibición de la enzima COX-2; y los efectos colaterales, del bloqueo de la COX-1. Entre tanto la isoforma COX-2 ha sido detectada constitutivamente en tejidos normales, levantando la duda sobre lo cuanto realmente son seguros los inhibidores específicos de esta enzima. El objetivo de esta revisión es relatar las más recientes evidencias clínicas y experimentales envolviendo la COX-2 y los compuestos inhibidores de esta isoforma. CONTENIDO: Son mostrados los nuevos conceptos sobre las diferencias estructurales entre COX-1 y COX-2, la existencia de estas isoformas en los diversos tejidos, los resultados de experimentos en animales y humanos, además de la observación clínica de los compuestos inhibidores específicos COX-2 (coxibs. Se enfatizan las posibles nuevas indicaciones de antiinflamatorios en los esteróides, principalmente coxibs, en la demencia de Alzheimer y en neoplasias. CONCLUSIONES: Los coxibs representan importante avanzo farmacológico en el tratamiento antiinflamatorio, reduciendo la incidencia de graves lesiones gastrointestinales y presentando posible indicación en la prevención de neoplasias y enfermedades neurológicas. Sin embargo, persisten efectos colaterales indistinguibles de los AINES convencionales y son drogas de alto costeo. Como toda medicación de reciente lanzamiento en el arsenal médico, mayores evaluaciones son necesarias para el establecimiento de la real seguridad de estos compuestos.BACKGROUND AND OBJECTIVES: Due to the high incidence of NSAID-related side-effects, the discovery of two cycloxygenase isoforms, classified as: COX-1 or constitutive and COX-2 or inductive, has formulated the paradigm that NSAIDs anti-inflammatory properties would be mediated by COX-2 inhibition, and side-effects, by COX-1 blockade. However, COX-2 has been constitutively detected in normal tissues

  17. sujetos a Efectos de Red

    Directory of Open Access Journals (Sweden)

    José Luis Arroyo Barrigüete

    2005-01-01

    Full Text Available El objetivo del presente artículo es analizar una de las principales características de la Economía Digital: las Externalidades de Red. Dichas Externalidades inducen en los mercados una realimentación positiva que lleva en muchos casos a situaciones prácticamente monopolísticas. Se identificarán aquellas capacidades internas de las empresas que resultan críticas para lograr el éxito en presencia de Efectos de Red así como las principales estrategias que es posible desarrollar en este contexto.

  18. Mass transport in aqueous zinc chloride-potassium chloride electrolytes

    Energy Technology Data Exchange (ETDEWEB)

    Leaist, D.G.

    1986-09-01

    Conductimetric and diaphragm cell techniques have been used to measure ternary diffusion coefficients for aqueous zinc chloride-potassium chloride solutions at 25/sup 0/C. At low concentrations where Zn/sup 2 +/ is the major zinc-transporting species, the diffusion-induced electric field along zinc chloride concentration gradients drives large co-current flows of potassium chloride. In concentrated solutions where a large proportion of zinc diffusses as anionic ZnCl/sub 3//sup -/ and ZnCl/sub 4//sup 2 -/ complexes, flow of zinc chloride generates counterflow of potassium chloride. If a sharp zinc chloride is formed in an otherwise uniform solution of potassium chloride, coupled diffusion can concentrate potassium ions within the diffusion boundary. Equations are developed to predict multicomponent transport coefficients for zinc chloride in supporting electrolytes.

  19. Evaluación del uso de los inhibidores de la bomba de protones en un servicio de medicina interna Assessing the use of proton pump inhibitors in an internal medicine department

    Directory of Open Access Journals (Sweden)

    E. Martín-Echevarría

    2008-02-01

    Full Text Available Introducción: los inhibidores de la bomba de protones (IBP bloquean la enzima H+/K+ ATPasa en las células parietales gástricas, logrando la inhibición de la secreción de ácido clorhídrico de forma basal como tras estimulación. Las indicaciones apropiadas para su uso son: enfermedad por reflujo gastroesofágico, hemorragia digestiva aguda, úlceras activas, gastritis o esofagitis erosiva, dispepsia, gastropatía por AINE, profilaxis de úlcera de estrés en pacientes de riesgo. El objetivo del estudio fue la revisión de las indicaciones de los IBP en nuestro medio y la evaluación de su utilización en el Hospital Universitario de Guadalajara. Material y métodos: se realizó un estudio de corte transversal analítico con selección aleatoria de los pacientes atendidos en el Servicio de Medicina Interna durante todo el año 2003. Se revisaron un total de 208 historias de 832 pacientes (un 25% a los que se administraron IBP. La edad media fue de 67 años (rango 16-92, el 46,2% fueron mujeres y las enfermedades subyacentes más frecuentes fueron: HTA, EPOC y DM. Resultados: un 34,6% de los pacientes tomaban IBP antes del ingreso. De estos, el 68,1% no tenía indicación. Durante el ingreso se prescribió de forma inadecuada el IBP al 73,07% y al alta, se mantenía el IBP sin indicación correcta. Conclusiones: los resultados están en concordancia con los anteriormente publicados, manteniéndose una alta frecuencia de uso incorrecto de los IBP y siendo recomendable una utilización más racional para evitar los efectos secundarios, las interacciones con otros fármacos y aportar una atención médica más eficiente.Introduction: proton pump inhibitors (PPIs block the H+/K+ ATPase enzyme in gastric wall cells, leading to an inhibition of both baseline and stimulated acid secretion. Appropriate indications include: Gastroesophageal reflux, acute upper gastrointestinal bleeding, erosive gastritis or esophagitis, dyspepsia, NSAID

  20. Participación de las hormonas gonadales en el efecto de los fármacos antidepresivos en la rata macho

    Directory of Open Access Journals (Sweden)

    Lucía Martínez-Mota

    2012-01-01

    Full Text Available Se ha propuesto que las hormonas gonadales participan en la regulación del estado de ánimo en los varones, y en el efecto de los fármacos psicoactivos, tales como los antidepresivos. Sin embargo, la evaluación de este tipo de interacciones ha sido estudiada escasamente. El objetivo del presente trabajo fue determinar el papel que cumplen las hormonas testosterona (T y 17β-estradiol (E2, uno de sus principales metabolitos, en el efecto de dos fármacos antidepresivos utilizados en la práctica clínica, desipramina y fluoxetina. El primero es un tricíclico con acciones sobre el sistema noradrenérgico, mientras que la fluoxetina es un inhibidor selectivo de la recaptura de serotonina. Las evaluaciones se llevaron a cabo utilizando ratas macho adultas jóvenes, gonadalmente intactas u orquidectomizadas (Orx, bajo tratamiento con T (0-1 mg/rata, E2 (0-40 μg/rata, desipramina (0-20 mg/kg, fluoxetina (0-20 mg/kg y sus respectivas combinaciones. Se utilizó la prueba de nado forzado (PNF para detectar las acciones antidepresivas de los tratamientos. Encontramos que desipramina y fluoxetina redujeron la conducta de depresión en los machos gonadalmente intactos; sin embargo, el efecto de ambos tratamientos fue abolido por la orquidectomía. El tratamiento de restitución hormonal con E2, pero no con T, indujo acciones antidepresivas en los machos Orx. A su vez, cuando los animales Orx recibieron la restitución con T se produjo la recuperación del efecto antidepresivo de la desipramina, mientras que el E2 restableció las acciones antidepresivas de ambos fármacos. En conclusión, el principal andrógeno de origen testicular, la T, participa en la expresión del efecto de los fármacos antidepresivos explorados en el presente estudio, principalmente a través de su metabolito estrogénico, el E2. Estos resultados apoyan la idea de que una terapia adjunta de tratamientos hormonales y antidepresivos sería de beneficio para varones hipogonadales

  1. Chloride removal from vitrification offgas

    International Nuclear Information System (INIS)

    This study identified and investigated techniques of selectively purging chlorides from the low-level waste (LLW) vitrification process with the purge stream acceptable for burial on the Hanford Site. Chlorides will be present in high concentration in several individual feeds to the LLW Vitrification Plant. The chlorides are highly volatile in combustion type melters and are readily absorbed by wet scrubbing of the melter offgas. The Tank Waste Remediation System (TWRS) process flow sheets show that the resulting chloride rich scrub solution is recycled back to the melter. The chlorides must be purged from the recycle loop to prevent the buildup of excessively high chloride concentrations

  2. [Degradation of succinylcholine chloride].

    Science.gov (United States)

    Németh, G; Török, I; Paál, T

    1993-05-01

    Quantitative thin-layer chormatographic method has been developed for the investigation of the degradation of injection formulations containing succinylcholinium chloride. The method is based on the denistometric determination of the main degradation product, choline at 430 nm after visualization with iodine vapour. The stability of the injection was investigated under various storage conditions and it has been stated that considerable decomposition takes place during as short a period as one week. PMID:8362654

  3. Efectos adversos metabólicos y nutricionales asociados a la terapia biológica del cáncer

    Directory of Open Access Journals (Sweden)

    Sara Alonso Castellanos

    2014-02-01

    Full Text Available Introducción: Los diferentes tipos de cáncer constituyen una de las principales causas de morbi-mortalidad en el mundo. La terapia clásica antitumoral (cirugía, quimioterapia, radioterapia ha incrementado notoriamente la supervivencia. Las terapias biológicas, con mecanismos de acción selectivos y frecuentemente específicos, constituyen una incorporación relativamente reciente al tratamiento oncológico; entre las más utilizadas se incluyen: citoquinas, anticuerpos monoclonales e inhibidores de tirosin kinasa y de mTOR. Si bien están adecuadamente documentados los efectos adversos nutricionales y metabólicos asociados a la terapia clásica, tanto en literatura como en guías clínicas, no ocurre igual con la terapia biológica. Objetivo: Revisar la literatura al respecto y detallar de modo organizado los resultados obtenidos. Métodos: Se revisó la literatura indizada así como todas las fichas técnicas de los fármacos incluidos en las distintas familias mediante la Agencia Española del Medicamento y Productos Sanitarios a Julio de 2013. Se registran los síntomas y signos clínicos con teórica acción sobre el estado nutricional o metabólico. Resultados: Se describe la acción específica de cada familia. Se agrupan los posibles efectos adversos de cada una sobre el estado nutricional y metabolismo, detallando y diferenciándolos en tablas para una más fácil y cómoda revisión y consulta. Se observan como posibles efectos secundarios más prevalentes los relacionados con el apetito, aparato digestivo y alteraciones electrolíticas. Conclusiones: Los posibles efectos secundarios asociados a terapias biológicas son múltiples y aparecen con diferente frecuencia y gravedad. Es importante al utilizarlas conocer el impacto nutricional y metabólico que pueden presentar, para su prevención y tratamiento.

  4. El efecto fotoeléctrico

    Directory of Open Access Journals (Sweden)

    M. A. Rodríguez-Meza

    2006-01-01

    Full Text Available Se presenta una revisión del trabajo de Albert Einstein de 1905 que popularmente se conoce como del efecto fotoeléctrico, y por el cual se le otorgó el premio Nobel en 1921. Mostramos que para Einstein el efecto en sí no era importante, sino que estaba interesado en entender los procesos de emisión y absorción de radiación por la materia. Veremos también que al entender la termodinámica de la radiación electromagnética en una cavidad en equilibrio térmico a una temperatura dada, Einstein pudo plantear su hipótesis de los quanta que aplicó a tres fenómenos de interés en esos años, entre ellos el efecto fotoeléctrico.

  5. Efectos digitales de audio con Web Audio API

    OpenAIRE

    GARCÍA CHAPARRO, SAMUEL

    2015-01-01

    El presente trabajo consiste en un estudio de la capacidad de Web Audio API para el procesado de efectos de audio en tiempo real. De todos los efectos de audio posibles se han elegido el wah-wah, el flanger y el choris, efectos ampliamente empleados con guitarra eléctrica. Se crean funciones de lenguaje JavaScript que modelan el comportamiento de los efectos de audio elegidos, haciéndolas funcionar sobre una plataforma web HTML5. García Chaparro, S. (2015). Efectos digitales de audio con W...

  6. Valyl benzyl ester chloride

    Directory of Open Access Journals (Sweden)

    Grzegorz Dutkiewicz

    2010-02-01

    Full Text Available In the title compound (systematic name: 1-benzyloxy-3-methyl-1-oxobutan-2-aminium chloride, C12H18NO2+·Cl−, the ester group is approximately planar, with a maximum deviation of 0.040 (2 Å from the least-squares plane, and makes a dihedral angle of 28.92 (16° with the phenyl ring. The crystal structure is organized by N—H...Cl hydrogen bonds which join the two components into a chain along the b axis. Pairs of chains arranged antiparallel are interconnected by further N—H...Cl hydrogen bonds, forming eight-membered rings. Similar packing modes have been observed in a number of amino acid ester halides with a short unit-cell parameter of ca 5.5 Å along the direction in which the chains run.

  7. Estudio de los efectos de agentes anticolinérgicos y de inhibidores de fosfodiesterasa-5 sobre la estructura pulmonar en un modelo experimental de enfermedad pulmonar obstructiva crónica inducido por humo de tabaco en el cobayo

    OpenAIRE

    Domínguez Fandos, David

    2015-01-01

    Tesi realitzada a l'Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) / Fundació Clinic per la Recerca Biomèdica La enfermedad pulmonar obstructiva crónica (EPOC) es una patología prevenible caracterizada por una limitación al flujo aéreo progresiva y no completamente reversible, disnea, producción de esputo y tos crónica. La obstrucción al flujo aéreo se asocia a un proceso inflamatorio crónico en la vía aérea y el parénquima pulmonar en respuesta a partículas nocivas...

  8. Efectos de la administración de un inhibidor de la recaptación de serotonina, Sertralina, sobre los cambios inducidos por el estrés prenatal

    OpenAIRE

    Figueiredo Pereira de, Inês

    2016-01-01

    [ES] En las postrimerías del siglo pasado, se constató una vez más que las alteraciones causadas por estrés y ansiedad en la sociedad moderna, se encuentran entre los problemas de salud más comunes. Según la Organización Mundial de Salud (OMS), al menos el 25% de los adultos sufrirá alguna forma de trastornos por ansiedad en algún momento de su vida (Gordon y Hen, 2004; Anacker y cols., 2010), siendo las mujeres más susceptibles a este tipo de trastornos (Olff y cols., 2007). ...

  9. Efecto neuroprotector de factores de crecimiento, inhibidores de caspasas y calaínas ante la acción tóxica de la ceramica en un modelo neuronal mesencefálico dopaminérgico

    Directory of Open Access Journals (Sweden)

    Humberto Arboleda

    2005-03-01

    Full Text Available La cemida es un producto del metabolismo de los esfingolípidos, que induce diversas respuestas celulares incluyendo la apoptosis.  Debido a que diversas señales de estrés celular consideradas mediadores de la muerte neuronal dopaminérgica (citoquinas, citotóxicos y estrés ambiental, incrementan el nivel de ceramidas.

  10. Efecto inhibidor de metabolitos y compuestos fenólicos de extractos de arándano rojo frente a la adherencia de E. coli uropatógena

    OpenAIRE

    Esteban-Fernández, Adelaida; Martín-Álvarez, Pedro J.; Bartolomé, Begoña; Moreno-Arribas, M. Victoria; González de Llano, Dolores

    2014-01-01

    Trabajo presentado al XIX Congreso Nacional de Mirobiología de los alimentos: "Avances en Microbiología de los alimentos" celebrado en Zaragoza del 24 al 26 de septiembre de 2014.-- Premio a la mejor comunicación de interés médico.

  11. Los primeros minutos del efecto invernadero

    OpenAIRE

    Corominas, Josep

    2013-01-01

    Esta actividad práctica muestra cómo determinados gases absorben la radiación infrarroja (de longitud de onda larga), lo cual permite explicar lo que ocurre a gran escala en la atmósfera de la Tierra en el llamado «efecto invernadero».

  12. Diagnosis and treatment of congenital hemophilia with inhibitors: A Latin American perspective Diagnóstico y tratamiento de la hemofilia congénita con inhibidores: Una perspectiva latinomericana

    Directory of Open Access Journals (Sweden)

    Raúl Pérez Bianco

    2008-06-01

    Full Text Available The Committee of Latin America on the Therapeutics of Inhibitor Groups (CLOTTING is composed of a number of hemophilia specialists from Latin America. The group aims to encourage the adoption of a good standard of care for Latin American patients with hemophilia. The occurrence of inhibitors in patients with hemophilia poses clinical challenges, and it is estimated that between 1000 and 3 000 patients in Latin America are affected by hemophilia with inhibitors. There is an urgent need to establish a regional consensus and clinical guidelines for the diagnosis and treatment of these patients. We present an extensive review based on best current clinical practice and published literature, as seen from a Latin American perspective, taking into account the variable nature of hemophilia care available in the various countries in this Region.El Comité Latinoamericano sobre la Terapéutica de Personas con Inhibidores (CLOTTING está compuesto por un grupo de especialistas en hemofilia de Latinoamérica. El objetivo del grupo es promover la adopción de un estándar de tratamiento óptimo para los pacientes con hemofilia en Latinoamérica. La prevalencia de inhibidores en pacientes con hemofilia en Latinoamérica determina desafíos clínicos y se estima que de 1000 a 3000 pacientes en esta región están afectados con hemofilia e inhibidores. Existe una necesidad urgente de establecer un consenso regional y guías clínicas para el diagnóstico y tratamiento de estos pacientes. Nosotros presentamos una revisión exhaustiva basada en las mejores prácticas clínicas vigentes y en los datos publicados en la literatura, con una perspectiva latinoamericana, tomando en cuenta la variabilidad existente de los tratamientos de la hemofilia disponibles en los diferentes países de esta Región.

  13. Uso de glicolípidos sulfatados como promotores del crecimiento neurítico, la mielinización e inhibidores de la proliferación de astroglia y microglia

    OpenAIRE

    Nieto-Sampedro, Manuel; Fernández-Mayoralas, Alfonso; Doncel-Pérez, Ernesto; García-Álvarez, Isabel

    2012-01-01

    Uso de glicolípidos sulfatados como promotores del crecimiento neurítico, la mielinización e inhibidores de la proliferación de astroglia y microglia. Uso de un compuesto de fórmula I, donde R1 es un resto alquenilo C5- C25 que contiene uno o más enlaces carbono-carbono dobles, R2 se selecciona independientemente del grupo que consiste en metilo y metilo fluorado, al menos uno de R 3 y R4 es un grupo SO3M, donde M se selecciona del grupo que...

  14. Evaluación del uso de los inhibidores de la bomba de protones en un servicio de medicina interna Assessing the use of proton pump inhibitors in an internal medicine department

    OpenAIRE

    E. Martín-Echevarría; Pereira Juliá, A.; Torralba, M; G. Arriola Pereda; P. Martín Dávila; Mateos, J.; M. Rodríguez Zapata

    2008-01-01

    Introducción: los inhibidores de la bomba de protones (IBP) bloquean la enzima H+/K+ ATPasa en las células parietales gástricas, logrando la inhibición de la secreción de ácido clorhídrico de forma basal como tras estimulación. Las indicaciones apropiadas para su uso son: enfermedad por reflujo gastroesofágico, hemorragia digestiva aguda, úlceras activas, gastritis o esofagitis erosiva, dispepsia, gastropatía por AINE, profilaxis de úlcera de estrés en pacientes de riesgo. El objetivo del est...

  15. Mejoramiento de las propiedades de biomateriales dentales metálicos mediante el uso de inhibidores orgánicos : Análisis de biocompatibilidad de los biomateriales tratados

    OpenAIRE

    Morales, María Laura

    2014-01-01

    Objetivos: a) General: mejorar las propiedades, biocompatibilidad y durabilidad de biomateriales dentales metálicos (BMDM) de modo que una vez instalados en la cavidad oral, beneficien la calidad de vida del ser humano. b) Específicos: estudiar la estabilidad y citotoxicidad de BMDM en medios biológicos simulados, en presencia de nuevos inhibidores orgánicos de la corrosión y comparar los resultados con los obtenidos en su ausencia. Enfoque y planificación del trabajo: Evaluar el ...

  16. Uso de glicolípidos sulfatados como promotores del crecimiento neurítico, la mielinización e inhibidores de la proliferación de astroglia y microglia

    OpenAIRE

    Nieto-Sampedro, Manuel; Fernández-Mayoralas, Alfonso; Doncel-Pérez, Ernesto; García-Álvarez, Isabel

    2012-01-01

    Uso de glicolípidos sulfatados como promotores del crecimiento neurítico, la mielinización e inhibidores de la proliferación de astroglia y microglia. Uso de un compuesto de fórmula I, donde R1 es un resto alquenilo C5- C25 que contiene uno o más enlaces carbono-carbono dobles, R2 se selecciona independientemente del grupo que consiste en metilo y metilo fluorado, al menos uno de R 3 y R4 es un grupo SO3M, donde M se selecciona del grupo que consiste en...

  17. Tendencia de la tensión arterial en mujeres con hipertensión arterial esencial-estadio ii tratadas con un inhibidor de la enzima convertidora de angiotensina

    OpenAIRE

    Garcés Ferrer, Mario E.; López P., Luis A.; Holguín, Esperanza

    2013-01-01

    Objetivo: Valorar el comportamiento de la tensión arterial en un grupo de mujeres con hipertensión arterial esencial- estadio II tratadas con guinapril, un inhibidor de la enzima convertidora de angiotensina. Métodos: se realizó un estudio epidemiológico experimental del subgrupo de pruebas clínicas con autocontroles en 16 mujeres aquejadas por hipertensión arterial - estadio II. La observación de los datos de tensión arterial se realizó con esfigmomanómetro de mercurio en cuatro oportunidade...

  18. Incidencia de la adición de fibras metálicas y poliméricas sobre el proceso corrosivo del acero en el concreto reforzado con la inclusión de aditivos inhibidores de corrosión ante ambiente salino

    OpenAIRE

    Rodríguez Quiroga, José Luis

    2014-01-01

    El principal objetivo de la investigación es determinar el impacto de la adición de fibras metálicas y poliméricas sobre la corrosión del acero en el concreto reforzado ante un ambiente salino, al usar aditivos inhibidores de corrosión. Sobre vigas de concreto con refuerzo de acero, se compararon concretos con y sin macrofibras (metálicas y poliméricas). Se evaluaron cuatro tipos de aditivos inhibidores de corrosión: nitratos, nitritos, aminoalcoholes y un impermeabilizante bloqueador de p...

  19. Efficacy of triple therapy with a proton pump inhibitor, levofloxacin, and amoxicillin as first-line treatment to eradicate Helicobacter pylori Eficacia de una triple terapia con un inhibidor de la bomba de protones, levofloxacino y amoxicilina, como primer tratamiento, en la erradicación de Helicobacter pylori

    Directory of Open Access Journals (Sweden)

    M. Castro-Fernández

    2009-06-01

    PPI, clarithromycin and amoxicillin.Introducción: la triple terapia con un inhibidor de la bomba de protones, claritromicina y amoxicilina (IBP-CA es el tratamiento de primera elección más utilizado en la erradicación de H. pylori. La eficacia de este tratamiento está disminuyendo en los últimos años y se están valorando otras alternativas terapéuticas. Objetivos:valorar la eficacia, cumplimiento y seguridad de una triple terapia con un IBP, amoxicilina y levofloxacino, sustituyendo a la claritromicina, en la erradicación de H. pylori. Métodos: periodo de estudio: 2007-2008. Se incluyen 135 pacientes (65% mujeres, edad media de 53 años, con síntomas dispépticos e infección por H. pylori, constatada por positividad del test rápido de la ureasa, histología o prueba del aliento con urea-C13. Diagnósticos: dispepsia no investigada: 48,9%, dispepsia funcional: 36,3% y dispepsia ulcerosa: 14,8%. Se indica tratamiento con un inhibidor de la bomba de protones, a dosis habitual, amoxicilina 1 g y levofloxacino 500 mg (IBP-LA, administrados de forma conjunta en desayuno y cena, durante 10 días. Se valora el cumplimiento de la triple terapia y sus efectos adversos mediante interrogatorio y su eficacia mediante la negatividad de la prueba del aliento con urea-C13 practicada a las 6-8 semanas del término del tratamiento. Se compara la eficacia, por protocolo, del tratamiento con IBP-LA con la observada en un grupo control de 270 pacientes tratados con IBP-CA durante 10 días en los años 2006-2007. Resultados: 130/135 pacientes (96,2 del grupo de estudio completaron el tratamiento y el protocolo del seguimiento. La eficacia por intención de tratar fue del 71,8% (97/135 y por protocolo del 74,6% (97/130. Dieciséis pacientes (11,8% presentaron efectos adversos bien tolerados, excepto en 5 pacientes (3.7% que motivan el abandono del tratamiento. El tratamiento con IBP-CA resultó eficaz, por protocolo, en 204/270 (75,5% pacientes del grupo control. Conclusiones

  20. Sodium chloride, potassium chloride, and virulence in Listeria monocytogenes.

    OpenAIRE

    MYERS, E. R.; Dallmier, A W; Martin, S E

    1993-01-01

    Virulence, as determined in a mouse model, and the virulence factor activities of catalase, superoxide dismutase, and listeriolysin O were examined in a parental strain (10403S) and in a nonhemolytic mutant strain (DP-L224) of Listeria monocytogenes. The cells were propagated in media containing various concentrations of sodium chloride or potassium chloride. Strains 10403S and DP-L224 exhibited significant increases in catalase activity and listeriolysin O activity when grown in medium conta...

  1. Efecto de la atorvastatina en el tratamiento de la periodontitis crónica moderada

    Directory of Open Access Journals (Sweden)

    Miriam Rocha Navarro

    2008-01-01

    Full Text Available Introducción: Las estatinas son inhibidores de la hidroximetil-glutaril Coenzima A reductasa que han sido empleadas para el tratamiento de la hipercolesterolemia. Se ha reportado que tienen efectos favorables sobre el metabolismo óseo disminuyendo el riesgo de fracturas y en algunos estudios un aumento de la densidad mineral ósea. Por lo anterior, el objetivo de este estudio fue comparar el tratamiento periodontal más atorvastatina (ATV sobre los parámetros periodontales y hueso alveolar versus tratamiento periodontal más placebo en pacientes con periodontitis crónica moderada (PCM. Materiales y Métodos: Estudio controlado, doble ciego, aleatorizado, en el que participaron 38 pacientes con PCM de 35 a 65 años, a los cuales se les administró por tres meses un tratamiento con ATV (20 mg/día, n=19 o complejo B (grupo control n=19. Todos los pacientes recibieron el mismo tratamiento periodontal al inicio del estudio. Se tomaron muestras de sangre en ayuno para cuantificar glucosa, perfil de lípidos, fosfatasa alcalina, N-telopéptidos y 17-estradiol. Se evaluaron los siguientes parámetros periodontales: Profundidad de las bolsas periodontales, sangrado gingival, recesión gingival, pérdida de inserción, movilidad dental, y placa dentobacteriana, además de la distancia de la cresta ósea alveolar a la unión cemento esmalte (COA-UCE. Todas las mediciones se realizaron al inicio y al final del estudio. Para el análisis de los datos se utilizó la prueba t para muestras dependientes y su alternativa no paramétrica para observar diferencias entre los dos grupos. La corrección de Bonferroni para comparaciones múltiples fue calculada en base a los valores de P. Para observar diferencias entre los grupos por género y estado menopáusico se utilizó la prueba t para muestras independientes o su alternativa no paramétrica U de Mann-Whitney. Se consideró una p< 0.05 como significativa. Resultados: Los parámetros periodontales mejoraron

  2. Chloride channels in stroke

    Institute of Scientific and Technical Information of China (English)

    Ya-ping ZHANG; Hao ZHANG; Dayue Darrel DUAN

    2013-01-01

    Vascular remodeling of cerebral arterioles,including proliferation,migration,and apoptosis of vascular smooth muscle cells (VSMCs),is the major cause of changes in the cross-sectional area and diameter of the arteries and sudden interruption of blood flow or hemorrhage in the brain,ie,stroke.Accumulating evidence strongly supports an important role for chloride (Clˉ) channels in vascular remodeling and stroke.At least three Clˉ channel genes are expressed in VSMCs:1) the TMEM16A (or Ano1),which may encode the calcium-activated Clˉ channels (CACCs); 2) the CLC-3 Clˉ channel and Clˉ/H+ antiporter,which is closely related to the volume-regulated Clˉ channels (VRCCs); and 3) the cystic fibrosis transmembrane conductance regulator (CFTR),which encodes the PKA-and PKC-activated Clˉ channels.Activation of the CACCs by agonist-induced increase in intracellular Ca2+ causes membrane depolarization,vasoconstriction,and inhibition of VSMC proliferation.Activation of VRCCs by cell volume increase or membrane stretch promotes the production of reactive oxygen species,induces proliferation and inhibits apoptosis of VSMCs.Activation of CFTR inhibits oxidative stress and may prevent the development of hypertension.In addition,Clˉ current mediated by gammaaminobutyric acid (GABA) receptor has also been implicated a role in ischemic neuron death.This review focuses on the functional roles of Clˉ channels in the development of stroke and provides a perspective on the future directions for research and the potential to develop Clˉ channels as new targets for the prevention and treatment of stroke.

  3. Evolución de la fibrosis hepática en reclusos coinfectados por VIH y VHC que inician tratamiento con inhibidores de la proteasa potenciados

    Directory of Open Access Journals (Sweden)

    P. Saiz de la Hoya Zamácola

    2013-10-01

    Full Text Available Objetivos: Analizar la evolución de la fibrosis hepática medida por elastografía y pruebas bioquímicas en reclusos coinfectados por VIH y VHC que han iniciado tratamiento antirretroviral con lopinavir/ritonavir u otros inhibidores de la proteasa potenciados con ritonavir. Métodos: Estudio prospectivo, observacional y multicéntrico. Se comprobó durante 48 semanas la evolución de la fibrosis hepática medida mediante elastografía de transición (FibroScan y pruebas bioquímicas en población penitenciaria española coinfectada por VIH y VHC. Resultados: De los 94 pacientes incluidos, 54 (57,4% fueron seguidos durante 48 semanas. En la semana 48, no hubo cambios significativos en el grado de fibrosis medida mediante FibroScan (8,1 Kpa vs 8,3; p=0.20 o índice de FORNS (5,6 vs 5,1; p=0,50, aunque sí con el índice APRI (0.7 vs 0.6; p=0.05 y el índice FIB-4 (p=0,02. Cuando la medición se realizó en función del grado de fibrosis basal, se observó que el tratamiento redujo el porcentaje de pacientes con fibrosis basal de grado 3/4 (50% vs 15%; p=0,001, pero no hubo cambios en los que ya tenían basalmente grado 4 (20,4% vs 20,4%. Conclusión: Los reclusos coinfectados por VIH y VHC que inician tratamiento antirretroviral con lopinavir/ritonavir muestran una estabilización de la fibrosis hepática medida con FibroScan® tras un año de seguimiento. En conjunto, el tratamiento mejoró la fibrosis cuando la referencia de medición fue el índice APRI y el FIB-4, pero no con el índice FORNS o la elastografía.

  4. Chloride in vesicular trafficking and function.

    Science.gov (United States)

    Stauber, Tobias; Jentsch, Thomas J

    2013-01-01

    Luminal acidification is of pivotal importance for the physiology of the secretory and endocytic pathways and its diverse trafficking events. Acidification by the proton-pumping V-ATPase requires charge compensation by counterion currents that are commonly attributed to chloride. The molecular identification of intracellular chloride transporters and the improvement of methodologies for measuring intraorganellar pH and chloride have facilitated the investigation of the physiology of vesicular chloride transport. New data question the requirement of chloride for pH regulation of various organelles and furthermore ascribe functions to chloride that are beyond merely electrically shunting the proton pump. This review surveys the currently established and proposed intracellular chloride transporters and gives an overview of membrane-trafficking steps that are affected by the perturbation of chloride transport. Finally, potential mechanisms of membrane-trafficking modulation by chloride are discussed and put into the context of organellar ion homeostasis in general. PMID:23092411

  5. Stability of succinylcholine chloride injection.

    Science.gov (United States)

    Schmutz, C W; Mühlebach, S F

    1991-03-01

    The stability of succinylcholine chloride injection prepared by a hospital pharmacy was studied under a wide variety of conditions. Batches of succinylcholine chloride injection 10 mg/mL containing sodium chloride, methyl-4-hydroxybenzoate, hydrochloric acid, and water were prepared. Samples were tested for the effect of initial pH (3.0 and 4.2) and sterilization (steam treatment at 100 degrees C for 30 minutes and 121 degrees C for 20 minutes) on stability after three weeks; long-term stability under refrigeration (12, 17, and 23 months of storage at 4 degrees C); and the effect of storage temperature (4-6 degrees C, 20-26 degrees C, 35 degrees C, and 70 degrees C) and light exposure at various intervals up to 12 months. Samples were analyzed by thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC). Unlike heating at 121 degrees C, heating at 100 degrees C produced no significant loss of succinylcholine chloride, independent of the initial pH. Succinylcholine chloride was hydrolyzed only minimally over 23 months if the solution was stored at 4-6 degrees C. A 10% loss of drug content occurred if solutions were kept at 20-26 degrees C for five months, at 35 degrees C for one month, or at 70 degrees C for one day. Initial degradation was slowed if the solution was protected from light. The assessments by TLC proved to be more sensitive than the HPLC measurements. Succinylcholine chloride injection sterilized at 100 degrees C for 30 minutes can be stored for up to five months at room temperature if protected from light. The preparation is stable for at least two years under refrigeration. PMID:2028996

  6. EDITORIAL EFECTOS ADVERSOS DE MEDICAMENTOS: UNA PATOLOGÍA MULTIFORME RESPONSABILIDAD

    Directory of Open Access Journals (Sweden)

    Joan-Ramon Laporte

    2009-09-01

    Full Text Available Quizá todavía haya profesionales que, cuando oyen hablar de efectos adversos de medicamentos, piensen en erupciones cutáneas, discrasias hemáticas, shock anafiláctico o incluso malformaciones congénitas. Los citados son efectos adversos reales, pero relativamente raros. Además, son inesperados, no relacionados con la acción farmacológica, imprevisibles e independientes de la dosis. Son como una lotería terapéutica, que dependería de «la suerte».No obstante, cuando se examina la patología farmacológica que da lugar a atención médica, el panorama es muy diferente. Lo que predomina, por ejemplo en servicios hospitalarios de urgencias, son efectos adversos relacionados con la acción farmacológica de los medicamentos implicados: hemorragias graves por anticoagulantes y antiagregantes plaquetarios, insuficiencia renal e hiperpotasemia por inhibidores del eje renina-angiotensina, hiponatremia, caídas y fracturas por antidepresivos ISRS, intoxicación digitálica... Se trata de patologías relativamente frecuentes, esperables, relacionadas con la dosis y favorecidas por la comorbididad del paciente, en gran parte evitables si la dosis del fármaco hubiera sido cuidadosamente individualizada, si el paciente hubiera seguido mejor las instrucciones (en caso de que las comprendiera bien o si el seguimiento clínico hubiera sido más cuidadoso.Una ojeada a la bibliografía reciente nos recuerda otras patologías, atendidas en otros niveles asistenciales. Por ejemplo: - Cáncer de mama atribuïble al tratamiento hormonal sustitutivo (THS: entre 3 y 4 casos adicionales por cada 1.000 tratadas durante 5 años, lo que aplicado a las cifras de ventas de estos productos en los años 1993 a 2003 se traduce en miles de casos adicionales de cáncer de mama inducidos por este tratamiento. Que por cierto fue promovido de manera irresponsable para la prevención cardiovascular, de la demencia y como fuente de juventud eterna, sin que hubiera (ni

  7. Chloride binding of cement-based materials subjected to external chloride environment - A review

    OpenAIRE

    Yuan, Q.; Shi, C; Schutter, G. de; Audenaert, K.; Deng, D.

    2009-01-01

    This paper reviews the chloride binding of cement-based materials subjected to external chloride environments. Chloride ion exist either in the pore solution, chemically bound to the hydration products, or physically held to the surface of the hydration products. Chloride binding of cement-based material is very complicated and influenced by many factors, such as chloride concentration, cement composition, hydroxyl concentration, cation of chloride salt, temperature, supplementary cementing m...

  8. Análisis de la sensibilidad de biotipos de Lolium multiflorum a herbicidas inhibidores de la enzima ALS, ACCasa y Glifosato Sensitivity analysis of Lolium multiflorum biotypes to Glyphosate, ACCase and ALS-inhibiting herbicides

    Directory of Open Access Journals (Sweden)

    P. Diez De Ulzurrun

    2012-09-01

    Full Text Available A pesar de los avances logrados en el control de las malezas con el uso de herbicidas, el manejo de las mismas no se simplificó, sino que, al contrario, surgieron nuevos desafíos, como la aparición de resistencia a herbicidas. En 2007, se reportó en Lolium multiflorum el segundo caso de resistencia a glifosato detectado en Argentina. En el sudeste de la provincia de Buenos Aires se registraron fallas de control a campo en poblaciones de Lolium multiflorum debido a su resistencia a distintos herbicidas de las familias de los inhibidores de ALS y de ACCasa y al herbicida glifosato. El objetivo de este estudio fue caracterizar el nivel de resistencia a ciertos herbicidas inhibidores de la ALS y de la ACCasa y al glifosato en una población de L. multiflorum de Lobería (Bs As, Argentina supuestamente resistente (LmR. Se realizaron bioensayos en cajas de Petri y se determinó la GR50 mediante la variación en la longitud de coleoptile. Las curvas de dosis-respuesta se obtuvieron por medio de la ecuación log-logística. El biotipo LmR presentó resistencia múltiple a herbicidas con tres modos de acción diferentes: glifosato, inhibidores de ALS y de ACCasa. Dicho ensayo demostró la aparición de un biotipo de L. multiflorum con resistencia a múltiples principios activos.Despite progress in weed control using herbicides, management has not been simplified, but new challenges such as herbicides resistance have arisen. In 2007, a Lolium multiflorum population resistant to glyphosate was reported, as the second case of glyphosate resistant weeds in Argentina. In the southeast of Buenos Aires province, control failures in populations of L. multiflorum to different families of herbicide such as ALS and ACCase inhibitors and to glyphosate at field level have been registered. The aim of this study was to characterize the level of resistance to certain herbicides inhibitors of ALS, ACCase and glyphosate in a putatively resistant (LmR population of L

  9. Los inhibidores de las fosfodiesterasas en el tratamiento de la disfunción sexual eréctil The inhibitors of the phosphodiesterases in treatment of erectile sexual dysfunction

    Directory of Open Access Journals (Sweden)

    Manuel Correa Jáuregui

    2010-12-01

    Full Text Available La disfunción sexual masculina impone una carga significativamente negativa en la salud, en las relaciones interpersonales, en la autoestima y en la calidad de vida de los que la padecen. Hasta finales de la década de los 80, el tratamiento se limitaba a la terapia psicosexual y a los implantes peneanos, y la causa se atribuía principalmente a factores psicológicos. El surgimiento de los inhibidores orales de fosfodiesterasa 5 con el lanzamiento del sildenafil (viagra en 1998, constituyó desde sus inicios una verdadera revolución y son ahora la primera elección del tratamiento en la disfunción eréctil, por ser bien tolerados, eficaces, no invasivos y con buenas tasas de respuesta.En el siguiente artículo se realizó una revisión del uso de los inhibidores de las fosfodiesterasas en el tratamiento de la disfunción sexual eréctil, así como las características relevantes de los medicamentos más usados en la actualidad, lo que contribuirá al conocimiento y a su mejor prescripción. Con este objetivo se consultaron los trabajos más actuales publicados en Pubmed y Medline. Los inhibidores de las fosfodiesterasa (sildenafil, vardenafil y tadalafil constituyen los medicamentos de elección en el tratamiento de la disfunción eréctil por su probada eficacia, seguridad y tolerancia.The male sexual dysfunction imposes a significantly negative burden in health, in the interpersonal relations, in self-esteem, and the quality of life of those suffering it. Up to at the end of the 80 decade, treatment was limited to psychosexual therapy and to penile implants and the cause was due to mainly to psychological factors. The appearance of oral inhibitors of phosphodiesterase-5 like the Sildenafil citrate (Viagra in1998, was from its onsets a real revolution and now are the first choice for treatment of erectile dysfunction because it is well tolerated, effective, non-invasive and with a good response rate. In present paper authors made a review

  10. Efectos garrapaticidas de algunos aceites esenciales

    OpenAIRE

    Juan F. Gil; Burillo Alquézar, Jesús; Pastor, Ana; Ringuelet, Jorge; Elder, Heriberto; Echeverri, Fernando

    2013-01-01

    Soluciones acuo-etanólicas de aceites esenciales de Lippia (3 quimiotipos), Schinus molle, Tagetes, Lavandina (dos quimiotipos), Hisopo, Romero y Ciprés, fueron sometidas a ensayos in Vitro para evaluar sus efectos sobre le supervivencia y reproducción de las garrapata Rhipicephalus (Boophilus) microplus. Los aceites de Lippia, Tagetes e Hisopo mostraron buenos niveles de inhibición de la oviposición y de mortalidad superiores al 50%, a una concentración del 1%; no obstante, a concentracio...

  11. Efecto de masticar chicle sobre la halitosis

    OpenAIRE

    De Luca Monasterios, Fiorella; Chimenos Küstner, Eduardo; López López, José

    2014-01-01

    Fundamento y objetivo: Este estudio pretende estimar la prevalencia de halitosis oral en una población joven y mostrar el efecto del chicle sobre el aliento. Pacientes y método: Estudio prospectivo de campo descriptivo correlacional, de corte transversal. Se seleccionaron a conveniencia 121 jóvenes, de los que 98 concluyeron el estudio, el cual se realizó en el Hospital Odontológico Universitario-Universidad de Barcelona. El protocolo consistió en: cuestionario, evaluación clínica oral, prueb...

  12. 1,5-Diaminotetrazolium chloride

    Directory of Open Access Journals (Sweden)

    Ling-Qiao Meng

    2010-04-01

    Full Text Available The title compound, CH5N6+·Cl−, crystallized with two indepedent 1,5-diaminotetrazolium cations and two independent chloride anions in the asymmetric unit. In the crystal, there are a number of N—H...Cl hydrogen-bonding interactions, which generate a three-dimensional network.

  13. Anti-inflamatórios não esteroides: Efeitos cardiovasculares, cérebro-vasculares e renais Antiinflamatorios no esteroides: efectos cardiovasculares, cerebrovasculares y renales Nonsteroidal anti-inflammatory drugs: cardiovascular, cerebrovascular and renal effects

    Directory of Open Access Journals (Sweden)

    Michel Batlouni

    2010-04-01

    inhibidores de la ciclo-oxigenase (COX, selectivos o no. Los AINEs no selectivos son los más antiguos, y designados como tradicionales o convencionales. Los AINEs selectivos para la COX-2 se designan COXIBEs. En los últimos años, ha sido cuestionada la seguridad del uso de los AINEs en la práctica clínica, particularmente de los inhibidores selectivos de la COX-2. Las evidencias sobre el aumento del riesgo cardiovascular con el uso de AINEs son todavía incompletas, debido a la ausencia de ensayos randomizados y controlados con poder para evaluar desenlaces cardiovasculares relevantes. Sin embargo, los resultados de estudios clínicos prospectivos y de metaanálisis indican que los inhibidores selectivos de la COX-2 ejercen importantes efectos cardiovasculares adversos, que incluyen aumento del riesgo de infarto del miocardio, accidente cerebrovascular, insuficiencia cardiaca, insuficiencia renal y hipertensión arterial. El riesgo de estos efectos adversos es mayor en pacientes con historia previa de enfermedad cardiovascular o con alto riesgo para desarrollarla. En estos pacientes, el uso de inhibidores de la COX-2 debe ser limitado a aquellos para los que no hay alternativa apropiada y, aun así, solamente en dosis bajas y por el menor tiempo necesario. Aunque los efectos adversos más frecuentes se relacionen a la inhibición selectiva de la COX-2, la ausencia de selectividad para esta isoenzima no elimina completamente el riesgo de eventos cardiovasculares, de modo que todos los fármacos del largo espectro de los AINEs se deben prescribir solamente tras consideración del balance riesgo/beneficio.The nonsteroidal anti-inflammatory drugs (NSAIDs are among the most often prescribed drugs in the world. This heterogeneous class of drugs includes aspirin and several other selective or non-selective cyclooxygenase (COX inhibitors. The non-selective NSAIDs are the oldest ones and are called traditional or conventional NSAIDs. The selective NSAIDs are called COX-2

  14. Estudio Teórico Preliminar de Fármacos Anti-VIH, Inhibidores No Nucleosídicos de la Transcriptasa Reversa Preliminary Theoretical Study on HIV-1, Non-Nucleoside Reverse Transcriptase Inhibitors

    Directory of Open Access Journals (Sweden)

    Martín A Dragonetti

    2008-01-01

    Full Text Available Una serie de compuestos derivados de quinoxalina, benzoxazina y benzodiazepina fue utilizada para realizar un estudio teórico preliminar que permita plantear un potencial grupo farmacóforo que conduzca a la síntesis de posibles inhibidores no-nucleosídicos de la transcriptasa reversa del virus del SIDA. El estudio teórico se llevó a cabo utilizando modelado molecular asistido por computadora. Se analizaron las conformaciones obtenidas para los compuestos en estudio (densidad atómica de carga y del arreglo espacial de los grupos atómicos. Los resultados se compararon con la información aportada por los complejos cristalográficos (fármaco-transcriptasa reversa extraídos de una base de datos de proteínas. Este estudio permitió establecer los requerimientos esenciales para que un compuesto se comporte como inhibidor de la transcriptasa reversa del VIH-1 y encontrar el potencial farmacóforo común a este tipo de fármacos.A series of quinoxaline, benzooxazine and benzodiazepine derivatives was selected to perform a preliminary theoretical study tending to find a potential pharmacophoric group that could lead to the synthesis of non nucleoside inhibitors of the HIV-1 reverse transcriptase. The theoretical study was performed using computer-assisted molecular modeling. The achieved final conformations of the selected compounds were compared and analyzed in terms of the atomic charge density and the atomic groups arrangements. The results were compared with information extracted from the crystallographic complexes (drug-reverse transcriptase reported in a protein data bank. This analysis enables to establish the essential requirements for a compound inhibition behavior of the HIV-1 reverse transcriptase and to find a potential pharmacophore common to this type of compounds.

  15. Estudio comparativo del comportamiento electroquímico del hierro en medio alcalino en presencia de lodos rojos y lodos grises. Efecto del Al3+

    Directory of Open Access Journals (Sweden)

    Abreu, C. M.

    2009-02-01

    Full Text Available Red mud (RM is the main by-product of the Bayer process for alumina extraction from bauxite, and grey slurries (GS are generated during the granite rocks transformation processes. The huge volume of those wastes generated every year suppose a serious environmental problem. Recent works by our group demonstrate the efficiency of both types of muds as corrosion inhibitors for iron and steel in alkaline media containing chlorides. The elemental analysis of these slurries shows that Al3+ is the main common element. Therefore, the aim of this paper is to study the effect of the soluble Al3+ in the electrochemical behaviour of iron in alkaline media, in presence and absence of chlorides. The electrochemical study using Cyclic Voltammetry (CV and Electrochemical Impedance Spectroscopy (EIS together with surface analysis techniques allowed to conclude that Al3+ blocks the surface of steel in alkaline media chloride increasing the steel resistance to chloride attack.

    Los elevados volúmenes de residuos generados por los lodos rojos (LR, procedentes del proceso de obtención de la alúmina a partir de la bauxita y los lodos grises (LG, originados durante el proceso de la transformación del granito, suponen un grave problema medioambiental. Trabajos recientes de este grupo demuestran la eficacia de ambos tipos de lodos como inhibidores de la corrosión del hierro y acero en medio alcalino clorurado. Esta característica ha llevado al estudio individualizado de sus componentes mayoritarios y, dentro de éstos, el Al3+, elemento común presente en mayor proporción. El estudio mediante técnicas electroquímicas como la Voltametría Cíclica (VC y la Espectroscopía de Impedancia Electroquímica (EIE, apoyadas en técnicas de análisis químico y superficial, ha permitido visualizar cómo el Al3+ es capaz de bloquear la superficie del acero en medio alcalino aumentando su resistencia al ataque

  16. Progress of Carbonation in Chloride Contaminated Concretes

    OpenAIRE

    Wang, Yaocheng; Basheer, P.A.M.; Nanukuttan, S; Bai, Y.

    2016-01-01

    Concretes used in marine environment are generally under the cyclic effect of CO2 and chloride ions (Cl-). To date, the influence of carbonation on ingress of chloride ions in concretes has been widely studied; in comparison, study on the influence of Cl- on the progress of carbonation is limited. During the study, concretes were exposed to independent and combined mechanisms of carbonation and chloride ingress regimes. Profiles of apparent pH and chloride concentration were used to indicate ...

  17. Chloride sublimation of gold-arsenic concentrates

    International Nuclear Information System (INIS)

    Present article is devoted to chloride sublimation of gold-arsenic concentrates. The results of studies of chloride sublimation of gold-arsenic comprising concentrates of Chore deposit of Tajikistan are considered. It is found that by application sodium chloride for gold-arsenic comprising concentrates it is possible to extract gold and silver from flotation concentrates.

  18. 21 CFR 582.5446 - Manganese chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Manganese chloride. 582.5446 Section 582.5446 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5446 Manganese chloride. (a) Product. Manganese chloride. (b) Conditions of use....

  19. El efecto abanico y la paradoja del experto

    OpenAIRE

    Gómez-Ariza, Carlos J.

    2010-01-01

    La investigación sobre la memoria ha demostrado que conocer más hechos sobre algo conlleva un incremento en el tiempo de reconocimiento de información al respecto (el efecto abanico). Aunque explicable por teorías de amplio espectro sobre la cognición humana, este efecto de interferencia plantea una paradoja: ¿cómo es posible entonces que un experto en un tema no sucumba ante los efectos de la interferencia durante la recuperación? La respuesta parece estar relacionada con la capacidad para i...

  20. El efecto coagulante de la digital

    OpenAIRE

    Naranjo Villegas, Alfredo

    2011-01-01

    Se lleva a cabo un trabajo para determinar el efecto coagulante de las dosis terapéuticas de digital, empleando las técnicas de Howell, de Lee y White, y de Quick. No se encontró modificación de la protrombina en los casos observados con el método de Howell. Se encontró aceleración del tiempo de protrombina -método de Quick - en 5 de 6 casos. Hubo aceleración de la coagulabilidad sanguínea - técnica de Lee y White - en 13 de 24 cardíacos digitalizados. Las dosis que más favorecieron el ...

  1. EFECTO DEL PARATHION SOBRE EL ÍNDICE DE APOPTOSIS EN HEPATOCITOS DE RATONES CF1 EFFECT OF PARATHION ON THE APOPTOSIS OF CF1 MOUSE HEPATOCYTES

    Directory of Open Access Journals (Sweden)

    Omar Espinoza

    2002-01-01

    Full Text Available En las últimas décadas el uso masivo de agropesticidas órganofosforados, como Parathion y Malathion, ha permitido el control de plagas en la producción hortofrutícola, mejorando la productividad e incrementando la oferta de alimentos de mayor calidad. Sin embargo, pese a su efectividad, estos compuestos químicos son potenciales causantes de daños morfológicos y genéticos, de alto riesgo para la Salud Humana y animal (Draper, 1985; Rodríguez y Bustos-Obregón, 2000. El parathion" (PT, inhibidor de la acetilcolinesterasa, se metaboliza en hígado, pulmón y cerebro. El efecto tóxico se debe a un proceso de desulfuración oxidativa hepática, que transforma el PT en paraoxon (PO, siendo éste su metabolito activo (Chambers y Chambers, 1990; Siller et al., 1997. El objetivo del presente trabajo es evaluar los efectos de una dosis única de PT sobre los índices de apoptosis en hepatocitos de ratón CF1. Se usaron ratones macho CF1 de 8 a 10 semanas, con un peso promedio de 30 g, a los cuales se les aplicó una dosis intraperitoneal única de PT de 20 mg/Kg de peso (Sobarzo y Bustos-Obregón, 2000. Posteriormente fueron sacrificados a 1, 8, 16, 28 y 50 días postratamiento. El análisis histológico del hígado se realizó mediante microscopía óptica sobre cortes teñidos con hematoxilina/eosina en que se analizó la presencia y frecuencia de hepatocitos apoptóticos. Los resultados obtenidos permiten demostrar el efecto del PT sobre el hepatocito con un aumento estadísticamente significativo de apoptosis. Se postula que el PT es carcinogénico, que bloquea o modifica la capacidad de replicación de los hepatocitos, alterando la susceptibilidad del tejido hepático (Fausto, 2000; Metcalfe y Streuli, 1997. Se concluye que el PT tiene un efecto tóxico, aún en dosis consideradas bajas, aumentando significativamente los índices de eventos apoptóticos, alterando el ciclo celular y afectando la histofisiología del tejido hep

  2. Determination of the constants of the solubility product of Ln(OH){sub 3} and the effect of the chloride ions on the lanthanum hydrolysis, praseodymium and lutetium in aqueous solutions of ion force 2 Molar; Determinacion de las constantes del producto de solubilidad de Ln(OH){sub 3} y el efecto de los iones cloruro sobre la hidrolisis de lantano, praseodimio y lutecio en soluciones acuosas de fuerza ionica 2 Molar

    Energy Technology Data Exchange (ETDEWEB)

    Lopez G, H.D

    2005-07-01

    The behavior of lanthanum (III), praseodymium (III), and lutetium (III) was studied in 2 M NaClO{sub 4} (aq) and 2 M NaCl (aq) at 303 K and free -CO{sub 2} conditions. Solubility diagrams (p Ln(aq)-pC{sub H}) were obtained by means of a radiochemical method. The pC{sub H} borderlines of saturation and unsaturation zones of the solutions and solubility product constants for Ln(OH){sub 3} were determined from these diagrams. The fitting of the solubility equation to the experimental values of p Ln(aq)-pC{sub H} diagrams allowed the calculation of the first hydrolysis and solubility product constants. Independently, the stability constants for the first species of hydrolysis were determined by means of pH titrations, the data were treated with the program SUPERQUAD and fitted to the mean ligand number equation. The stability constants for the species LnCl{sup 2+} were as well calculated in 2M ionic strength and 303 K from the hydrolysis constant values obtained in both perchlorate and chloride media. The values obtained for La, Pr and Lu were: logK{sub ps}: 21.11 {+-} 0.09, 19.81 {+-} 0.11 and 18.10 {+-} 0.13 in 2M NaClO{sub 4}; logK{sub ps}: 22.22 {+-} 0.09, 21.45 {+-} 0.14 and 18.52 {+-} 0.29 in 2M NaCl; log {beta}{sub 1}: - 8.64 {+-} 0.02, - 8.37 {+-} 0.01 and - 7.95 {+-} 0.11 in 2M NaClO{sub 4}; log {beta}{sub 1}{sup /} : - 9.02 {+-} 0.11, - 8.75 {+-} 0.01 and - 8.12 {+-} 0.03 in 2M NaCl and the values for log {beta}{sub 1,Cl} were - 0.0255, - 0.155 and - 0.758, respectively. (Author)

  3. Neutron diffraction study of aluminum chloride imidazolium chloride molten salts

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, S. [Nisshin Steel Co. Ltd., Tokyo (Japan); Saboungi, M.L.; Suzuya, K. [Argonne National Lab., IL (United States); Koura, N. [Tokyo University of Science, Tokyo (Japan). Faculty of Science and Technology

    1994-02-01

    The structure of molten mixtures of (AlCl{sub 3}){sub x}(1-ethyl-3-methylimidazolium chloride){sub 1-x} was investigated by neutron diffraction techniques for x=0.46, 0.50, 0.60 and 0.67. Results derived from earlier ab initio molecular orbital (6-31G* basis set) computations for AlCl{sub 4}{sup {minus}}, Al{sub 2}Cl{sub 7}{sup {minus}}, and EMI{sup +} were used to calculate the diffraction patterns; the calculated contributions of each species are thus obtained and overall results are in good agreement with measurements.

  4. Inorganic inhibitor study in the steel corrosion in the mixture of LiBr+Etilenglicol+H{sub 2}O; Estudio de inhibidores inorganicos en la corrosion de aceros en la mezcla de LiBr+Etilenglicol+H{sub 2}O

    Energy Technology Data Exchange (ETDEWEB)

    Sarmiento Bustos, Estela

    2008-07-15

    develop this work. Fourth chapter is the results presentation and discussion divided in four sections: each one for material electrochemically tested in the LiBr+ etilene glycol+ H{sub 2}O solution. Also presents the results obtained for the extended study made to carbon steel under different temperature and electrochemical test conditions. This includes the EIS and electrochemical noise Hurst results analysis and simulations. Finally, the fifth chapter presents the conclusions and recommendations of this work. An appendix with the solution preparation is included. [Spanish] En esta tesis doctoral se presentan los resultados obtenidos de cinetica electroquimica de la corrosion de 4 aceros: acero al carbon, 304, 316 y 316L, en una solucion de LiBr+ etilenglicol+H{sub 2}O. Estos sistemas son utilizados en bombas de calor por absorcion para la recuperacion de calor de desecho a la salida de procesos industriales. Sin embargo, la solucion absorbente es altamente corrosiva en este tipo de equipos. Por lo anterior se evaluaron tres diferentes inhibidores inorganicos: nitrato de litio, molibdato de litio y cromato de litio los cuales son fuertes oxidantes y promueven la formacion de la capa pasiva de los aceros y se aplicaron a diferentes temperaturas: 25, 50 y 80 grados dentigrados. A traves de tecnicas electroquimicas como curvas de polarizacion, ruido electroquimico, impedancia electroquimica, resistencia a la polarizacion lineal y mediciones de potencial de corrosion a circuito abierto en el tiempo. Se determino el compuesto inhibidor mas adecuado obteniendo su eficiencia bajo las diferentes condiciones, de los tres inhibidores considerados el que presento el mejor comportamiento y eficiencia para el acero al carbon fue el nitrato de litio a 50 ppm; para el 304 el cromato de litio a 5 ppm; para el acero 316 molibdato de litio a 5 ppm y para el 316L el cromato de litio a 5 ppm. Debido a que el acero al carbon es el material mas economico y presento una mejor respuesta por

  5. Synthesis of Zirconium Lower Chlorides

    International Nuclear Information System (INIS)

    This research is accurately related to the Halox concept of research reactor spent fuel element treatment.The aim of this project is to work the conditioning through selected chlorination of the element that make the spent fuel element. This research studied the physical chemistry conditions which produce formation of the lower zirconium chlorides through the reaction between metallic Zr and gaseous ZrCl4 in a silica reactor.This work focused special attention in the analysis and confrontation of the published results among the different authors in order to reveal coincidences and contradictions.Experimental section consisted in a set of synthesis with different reaction conditions and reactor design. After reaction were analyzed the products on Zr shavings and the deposit growth on wall reactor.The products were strongly dependent of reactor design. It was observed that as the distance between Zr and wall reactor increased greater was tendency to lower chlorides formation.In reactors with small distance the reaction follows other way without formation of lower chlorides.Analysis on deposit growth on reactor showed that may be formed to a mixture of SixZry intermetallics and zirconium oxides.Presence of oxygen in Zr and Zr-Si compounds on wall reactor reveals that there is an interaction between quartz and reactants.This interaction is in gaseous phase because contamination is observed in experiences where Zr was not in contact with reactor.Finally, it was made a global analysis of all experiences and a possible mechanism that interprets reaction ways is proposed

  6. Separación de la Mezcla Azeotrópica Acetona-Metanol con Cloruro de Litio Separation of an Azeotropic Acetone - Methanol Mixture Using Lithium Chloride

    Directory of Open Access Journals (Sweden)

    F. Anguebes-Franseschi

    2004-01-01

    Full Text Available Se ha determinado el efecto que tiene el cloruro de litio usado como agente extractivo para separar la mezcla azeotrópica acetona-metanol. La metodología establece la preparación de dos mezclas con diferentes concentraciones másicas de acetona-metanol, por debajo del punto azeotrópico: 85-15% y 75- 25%. En cada destilación realizada, se dosificó cloruro de litio a diferentes concentraciones para determinar el efecto de éste sobre la concentración de las mezclas y el punto azeotrópico. Los resultados determinan que a una concentración de 2.3 moles de cloruro de litio por kilogramo de solución, se obtiene el mayor efecto sobre el punto azeotrópico, considerando la manipulación del reflujo y la concentración de la sal. Se concluyó que es posible separar esta mezcla azeotrópica usando cloruro de litio como agente extractivoThe effect of lithium chloride when used as an extractive agent for separating the azeotropic mixture composed of acetone and methanol, was determined. The methodology included the preparation of two mixtures with different acetone-methanol mass concentrations, below the azeotropic point: 85-15% and 75-25%. For each distillation carried out, lithium chloride was added in different measured dosages to determine its effect on the composition of the mixtures and the azeotropic point. The results suggested that a concentration of 2.3 moles of lithium chloride per kg of solution produced the greatest effect on the azeotropic point, considering the reflux manipulation and salt concentration. It was concluded that it is possible to separate this azeotropic mixture using lithium chloride as an extractive agent

  7. Cooper hydrometallurgy and extraction from chloride media

    International Nuclear Information System (INIS)

    The development of copper hydrometallurgy is presented and various processes proposed for copper recovery from sulphide concentrates are discussed. Leaching, extraction and stripping are considered, including reagents and processes. The extraction of copper from chloride solutions is discussed. Various extractants are presented and their use for copper transfer from chloride solutions to the organic phase and back to chloride and to sulphate solutions is discussed. (author) 4 refs

  8. Dechlorinating reaction of organic chlorides

    International Nuclear Information System (INIS)

    Dechlorination has been examined by the reaction between iron, aluminum powder or CaO and organic chlorides such as C2HCl3 and CH2Cl2. Progress of the reaction was analyzed with mass spectrometer. The reaction between iron and organic chloride was rapidly occurred at the temperature between 350 and 440degC in an atmosphere of argon. Above 380degC, more than 99.5% of C2HCl3 was decomposed within approximately 100 minutes. At 440degC, approximately 60% of C2HCl3 was decomposed by the reaction with aluminium powder within approximately 100 minutes. At 440degC, reaction between C2HCl3 and CaO powder were occurred rapidly in an atmosphere of argon to form CaCl2 and free carbon. Also in an atmosphere of air, nearly the same result was obtained. In this reaction, CaCl2, CO and CO2 were formed. CH2Cl2 was also decomposed by the reaction with iron at the temperature between 380 and 440degC. In the reaction, FeCl2, carbon and hydrogen were formed. CH3+ and CH4 were observed during the dechlorinating reaction of CH2Cl2. Variation in particle size of iron powder such as 100, 150 and 250 mesh did not affect the reaction rate. (author)

  9. Method of processing chloride waste

    International Nuclear Information System (INIS)

    In a method of applying molten salt electrolysis to chloride wastes discharged from a electrolytic refining step of a dry reprocessing step for spent fuels, and removed with transuranium elements of long half-decaying time, metals capable of alloying with alkali and alkaline earth metals under melting by electrolysis are used as a cathode material, and an electrolytic temperature is made higher than the melting point of salts in a molten salt electrolysis bath, to recover Li, Ca and Na as alloys with the cathode material in a first electrolysis step. Then, the electrolytic temperature is made higher than the melting point of the chloride salts remained in the bath after the electrolysis step described above by using the cathode material, to recover Ba, Rb, Sr and Cs of nuclear fission products also as alloys with the cathode material in a second electrolysis step. Accordingly, the amount of wastes formed can be reduced, and the wastes contain no heat generating nuclear fission elements. (T.M.)

  10. Atmósferas modificadas, frigo conservación e inhibidores de oscurecimiento en poscosecha de Pleurotus ostreatus Modified atmospheres, cold storage and darkening inhibitors in postharvest Pleurotus ostreatus

    Directory of Open Access Journals (Sweden)

    Rosa Ventura-Aguilar

    2011-04-01

    Full Text Available Las setas presentan oscurecimiento y pérdidas de peso durante su vida poscosecha, afectando la calidad sensorial del producto; por ello el objetivo de este trabajo fue incrementar la vida útil de hongos mínimamente procesados del género Pleurotus ostreatus (Jacq. Quélet, mediante el uso de una película plástica (CP9250 CRYOVAC® y un testigo, tres diferentes temperaturas de almacenamiento (2 ±1 ºC, 5 ±1 ºC y 17 ±1 ºC e inhibidores de oscurecimiento: a 3% eritorbato de sodio + 1% ácido cítrico; b 1% eritorbato de sodio + 1% ácido cítrico; y c un testigo. Los resultados indican que mediante el uso de la película plástica se produjo una reducción en la respiración, comparado con el testigo, mermas en peso de 1%, reducción en la pérdida de luminosidad y menor actividad de la enzima polifenoloxidasa (EC1.10.3.1. El mejor tratamiento para prolongar la vida útil de Pleurotus fue la película plástica, con inhibidores de oscurecimiento (3% eritorbato de sodio + 1% ácido cítrico y almacenamiento a 2 ó 5 ºC.Mushrooms present darkening and weight losses during their post-harvest life, which affects sensorial quality for the product; this is the reason why aim of this work was to increase useful life of minimumly processed mushrooms from genus Pleurotus ostreatus (Jacq. Quélet, by means of plastic film (CP9250 CRYOVAC® and a control, three different storage temperatures (2 ±1 ºC, 5 ±1 ºC and 17 ±1 ºC and darkening inhibitors: a 3% sodium erythorbate + 1% citric acid; b 1% sodium erythorbate + 1% citric acid; and c control. The results indicate that by means of plastic film a reduction in breathing took place, compared with control, reduction in weight of 1%, reduction in loss of brightness and smaller activity of enzyme polyphenol oxidase (EC1.10.3.1. The best treatment to extend useful life of Pleurotus was plastic flm, with darkening inhibitors (3% sodium erythorbate + 1% citric acid and storage at 2 or 5 ºC.

  11. Green process to recover magnesium chloride from residue solution of potassium chloride production plant

    Institute of Scientific and Technical Information of China (English)

    Lin WANG; Yunliang HE; Yanfei WANG; Ying BAO; Jingkang WANG

    2008-01-01

    The green process to recover magnesium chlor-ide from the residue solution of a potassium chloride pro-duction plant, which comes from the leach solution of a potash mine in Laos, is designed and optimized. The res-idue solution contains magnesium chloride above 25 wt-%, potassium chloride and sodium chloride together below 5 wt-% and a few other ions such as Br-, SO2-4and Ca2+. The recovery process contains two steps: the previous impurity removal operation and the two-stage evapora-tion-cooling crystallization procedure to produce magnes-ium chloride. The crystallized impurity carnallite obtained from the first step is recycled to the potassium chloride plant to recover the potassium salt. The developed process is a zero discharge one and thus fulfills the requirements for green chemical industrial production. The produced magnesium chloride is up to industrial criteria.

  12. Efectos de la “mentalidad” conquistadora

    Directory of Open Access Journals (Sweden)

    Edison Viveros

    2011-01-01

    Full Text Available El autor hace un análisis del proceso de conquista y colonia de América. Utiliza una técnica de rastreo documental para examinar lo que denomina “mentalidad conquistadora” a través de sus expresiones históricas. Evalúa las particularidades políticas y económicas tanto de Europa como de América en esa época, con el fin de demostrar que el choque de dos cosmovisiones, una de corte bélico y conquistador, otra con una ética de hermandad y cuidado por la tierra y los ancestros, impidió un proceso que podría haber sido sincrético. Finalmente, concluye que, pese a los efectos de esta mentalidad, y de su permanencia en los rasgos culturales americanos, este continente es un espacio de mixturas y un mundo plural, con toda la potencialidad para ser auténtico.

  13. Sitagliptina, un inhibidor de la enzima DPP-IV, aumenta el colesterol plasmático total, altera el perfil de colesterol lipoproteico y disminuye el transporte reverso de colesterol en ratones Sitagliptine, an DPP-IV enzyme inhibitor, raises total cholesterol and decreases reversal cholesterol transport in mice

    Directory of Open Access Journals (Sweden)

    Andrea Leiva

    2010-01-01

    Full Text Available Antecedentes: Las hormonas insulina y glucagón regulan la expresión de proteínas claves en el metabolismo lipfdico. En pacientes diabéticos, la enfermedad cardiovascular ateroesclerótica es la principal causa de muerte, siendo la dislipidemia un importante factor de riesgo patogénico. La sitagliptina, un inhibidor de la enzima dipeptidilpeptidasa tipo IV (DPP-IV que controla el metabolismo de las incretinas, es una nueva droga hipogli-cemiante utilizada para el tratamiento de la diabetes tipo 2, aunque sus implicancias en el metabolismo lipfdico no han sido establecidas claramente. Objetivo: Estudiar el efecto de la sitagliptina sobre algunos parámetros relacionados con el metabolismo del colesterol en el ratón. Material y Métodos: Se utilizaron ratones C57BL6/J silvestres, siendo un grupo alimentado con dieta estándar y el otro con dieta estándar suplementada con sitagliptina (0,6% P/Pde dieta por 8 semanas. La actividad plasmática de DPP-IV y el colesterol plasmático total y lipoproteico fueron medidos por métodos enzima-ticos. La expresión hepática de SR-BI y LDLR se cuanti-ficó por western blot. El transporte reverso de colesterol (TRC fue evaluado inyectando intraperitonealmente ma-crófagos cargados con colesterol-14C y midiendo posteriormente los niveles de 14C en plasma y deposiciones en los ratones controles o tratados con sitagliptina. Resultados: La sitagliptina inhibió en un 38% la actividad de DPP-IV medida en plasma de los ratones. El colesterol plasmático aumentó significativamente (+60% con una elevación preferente del colesterol HDL en los ratones tratados con sitagliptina versus los animales controles. Con respecto al TRC, la sitagliptina indujo una mayor recuperación (+20% en el plasma y una menor excresión (-30% en las deposiciones del 14C-colesterol inyectado versus el grupo control. Finalmente, la sitagliptina disminuyó la expresión hepática de los receptores lipoproteicos LDLR y SR-BI. Conclusi

  14. Factors influencing chloride deposition in a coastal hilly area and application to chloride deposition mapping

    OpenAIRE

    H. Guan; Love, A. J.; C. T. Simmons; Makhnin, O.; A. S. Kayaalp

    2010-01-01

    Chloride is commonly used as an environmental tracer for studying water flow and solute transport in the environment. It is especially useful for estimating groundwater recharge based on the commonly used chloride mass balance (CMB) method. Strong spatial variability in chloride deposition in coastal areas is one difficulty encountered in appropriately applying the method. A high-resolution bulk chloride deposition map in the coastal region is thus needed. The aim of this study is to construc...

  15. Factors influencing chloride deposition in a coastal hilly area and application to chloride deposition mapping

    OpenAIRE

    H. Guan; Love, A. J.; C. T. Simmons; Makhnin, O.; A. S. Kayaalp

    2010-01-01

    Chloride is commonly used as an environmental tracer for studying water flow and solute transport in the environment. It is especially useful for estimating groundwater recharge based on the commonly used chloride mass balance (CMB) method. Strong spatial variability in chloride deposition in coastal areas is one difficulty encountered in appropriately applying the method. A high-resolution bulk chloride deposition map in the coastal region is thus needed. The aim of this st...

  16. Efecto neuroprotector del trasplante de Glía envolvente sobre la lesión del plexo braquial

    OpenAIRE

    Manuel Nieto Sampedro; C. Muñetón Gómez; Taylor, J. S.; V. Muñetón Gómez

    2005-01-01

    La disfunción irreversible ocasionada por las lesiones del SNC se debe en gran parte a la inducción de cambios celulares y moleculares, como la gliosis reactiva y la expresión de inhibidores de la neuritogénesis.

  17. Efecto neuroprotector del trasplante de Glía envolvente sobre la lesión del plexo braquial

    Directory of Open Access Journals (Sweden)

    Manuel Nieto Sampedro

    2005-03-01

    Full Text Available La disfunción irreversible ocasionada por las lesiones del SNC se debe en gran parte a la inducción de cambios celulares y moleculares, como la gliosis reactiva y la expresión de inhibidores de la neuritogénesis.

  18. Concrete Durability. Influence of chloride ions concentrations in mixing water and dissolution

    Directory of Open Access Journals (Sweden)

    López Villarino, Begoña

    1995-03-01

    Full Text Available The most aggressive situation which is responsible for most of the cases of steel reinforcement corrosion in concrete, takes place when chlorides are present in the environment. These chlorides destroy the passivating film of steel and promote the denominated pitting corrosion. In order to study the demonstrated corrosive action of chloride ions on concrete structures, a number of experiments have been designed, to quantify the effect of different amounts of this ion in concrete. Several mixes have been prepared with portland cement type II-C-35 to which it has been added, as an additive in mixing water, NaCl in increasing concentrations. The samples obtained were submerged in different dissolutions of NaCl. From the results obtained it is clear that the chloride content in mixing water does not affect the flux of calcium ions; however, its influence on the flux of chloride ions is significant. Likewise, it is confirmed that the existence of chloride ions in dissolution influences the migration of calcium and chloride ions.

    La situación más agresiva, y la responsable del mayor número de casos de corrosión de armaduras en el hormigón, se da cuando en el ambiente hay presencia de cloruros, pues éstos destruyen de forma puntual la capa pasivante del acero, lo que provoca la denominada corrosión por picaduras. Con objeto de estudiar la demostrada acción perniciosa de los cloruros sobre las estructuras de hormigón, se ha diseñado un conjunto de ensayos con el fin de cuantificar el efecto de las distintas cantidades de este ion en la masa de hormigón. Se han realizado diversas amasadas con cemento tipo II-C-35 a las que se añadió, como aditivo en el agua de amasado, NaCl en concentraciones crecientes. Las probetas obtenidas se sumergieron en disoluciones de NaCl de distintas concentraciones. De los resultados obtenidos se deduce que la presencia de cloruros en el agua de amasado no afecta al flujo de iones cálcicos, mientras

  19. Efecto de diferentes dosis de aspirina sobre el precondicionamiento contra el atontamiento en ovejas Effect of different doses of aspirin on preconditioning against stunning in conscious sheep

    Directory of Open Access Journals (Sweden)

    Elena C. Lascano

    2004-02-01

    Full Text Available Se ha postulado que los antiinflamatorios no esteroides que actuan inhibiendo la ciclooxigenasa (COX podrían tener efectos nocivos sobre el corazón. Recientemente se ha demostrado que los inhibidores de la COX-2 bloquean la protección por precondicionamiento tardío (PT. Se desconoce sin embargo, el efecto que pudiera tener la aspirina, el antiinflamatorio no esteroide más ampliamente utilizado en la clínica, sobre el PT en mamíferos grandes. La aspirina actúa inhibiendo las dos isoenzimas de la ciclooxigenasa (COX-1 y COX-2, siendo empleada en dosis altas como droga antiinflamatoria y en dosis bajas como agente antitrombótico. El propósito de este estudio fue analizar qué efecto tienen distintas dosis de aspirina sobre la protección del PT contra el atontamiento y las arritmias en ovejas conscientes. Se consideraron 5 grupos; control (C: 12 min de isquemia (I y 2 hr de reperfusión (R; PT: 6 períodos de 5 min I-5 min R, 24 hr antes de la I de 12 min, y tres grupos igual que PT, pero con 1.5 (PTA1.5, 8 (PTA8 y 20 (PTA20 mg/kg de aspirina respectivamente, administrados 10 min antes de la primera I de precondicionamiento. Los resultados demostraron que la dosis antiinflamatoria de aspirina (20 mg/kg fue capaz de inhibir el PT contra el atontamiento (C vs PTA20, NS, mientras que las dosis bajas (1.5 mg/kg e intermedia (8 mg/kg no afectaron la protección (C vs PT, PT1.5 y PT8, pNon-steroid antiinflammatory drugs, inhibitors of cyclooxigenase (COX, have been postulated to have deletereous effects on the heart. Recently, COX-2 inhibitors have also been found to block late preconditioning (LP protection. Aspirin is the most widely clinically used non-steroid antiinflammatory drug; yet its effect on LP in big mammals has not been determined. It inhibits the two cyclooxigenase isoenzymes (COX-1 and COX-2, at high doses being used as an antiinflammatory drug and at low doses as an antithrombotic agent. The goal of this study was thus, to

  20. Electrochemical Chloride extraction using external electrodes?

    DEFF Research Database (Denmark)

    Ottosen, Lisbeth M.; Pedersen, Anne Juul

    cathode. However, some unwanted side effects can occur, including alkali-silica reaction and in some cases hydrogen embrittlement. It is also suggested also to use electrochemical chloride extraction in a preventive way in constructions where chloride induced corrosion is likely to be a problem after a...

  1. Chloride binding site of neurotransmitter sodium symporters

    DEFF Research Database (Denmark)

    Kantcheva, Adriana Krassimirova; Quick, Matthias; Shi, Lei;

    2013-01-01

    Neurotransmitter:sodium symporters (NSSs) play a critical role in signaling by reuptake of neurotransmitters. Eukaryotic NSSs are chloride-dependent, whereas prokaryotic NSS homologs like LeuT are chloride-independent but contain an acidic residue (Glu290 in LeuT) at a site where eukaryotic NSSs...

  2. Chloride ingress in cement paste and mortar

    DEFF Research Database (Denmark)

    Jensen, Ole Mejlhede; Hansen, Per Freiesleben; Coats, Alison M.; Glasser, Fred P.

    1999-01-01

    In this paper chloride ingress in cement paste and mortar is followed by electron probe microanalysis. The influence of several paste and exposure parameters on chloride ingress are examined (e.g., water-cement ratio, silica fume addition, exposure time, and temperature), The measurements are...

  3. Chloride ingress in cement paste and mortar

    DEFF Research Database (Denmark)

    Jensen, Ole Mejlhede; Hansen, Per Freiesleben; Coats, Alison M.;

    1999-01-01

    modelled on Fick's law modified by a term for chloride binding. Inclusion of chloride binding significantly improves the profile shape of the modelled ingress profiles. The presence of fine aggregate and formation of interfacial transition zones at paste-aggregate boundaries does not significantly affect...

  4. Reliability-Based Planning of Chloride Measurements

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Engelund, S.

    1996-01-01

    on measurements of the chloride content obtained from the given structure. In the present paper optimal planning of measurements of the chloride content in reinforced concrete structures is considered. It is shown how optimal experimental plans can be obtained using FORM-analysis. Bayesian statistics...

  5. Properties of silver chloride track detectors

    International Nuclear Information System (INIS)

    The experiments on preparation of silver chloride track detectors and their properties are described. The results of X-ray structural analysis and data on sensitivity to charged particles and actinic light of silver chloride crystals, doped with several elements, are presented. (orig.)

  6. Diffusion behavior of chloride ions in concrete

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, T.; Gjoerv, O.E. [Norwegian Univ. of Science and Technology, Trondheim (Norway). Div. of Building Materials

    1996-06-01

    In the present paper, an analysis of the diffusion behavior of chloride ions in concrete is presented. In concentrated electrolytic aqueous solutions such as seawater or that typically used in laboratory experiments, the effect of ionic interaction may significantly reduce the chemical potential and thus the driving force of the diffusing species. Because of different drift velocities of the cations and chloride ions in the solution, the lagging motion of the cations will also retard the drift velocity of the chlorides. In addition, both the electrical double layer forming on the solid surface and the chemical binding may significantly interfere with the transport of the chloride ions. As a result, the diffusion behavior of the chloride ions in concrete is a more complex and complicated transport process than what can be described by Fick`s law of diffusion.

  7. Simple chloride sensors for continuous groundwater monitoring

    DEFF Research Database (Denmark)

    Thorn, Paul; Mortensen, John

    2012-01-01

    The development of chloride sensors which can be used for continuous, on-line monitoring of groundwater could be very valuable in the management of our coastal water resources. However, sensor stability, drift, and durability all need to be addressed in order for the sensors to be used in continu......The development of chloride sensors which can be used for continuous, on-line monitoring of groundwater could be very valuable in the management of our coastal water resources. However, sensor stability, drift, and durability all need to be addressed in order for the sensors to be used...... sensor remained responsive even at low chloride concentrations, where the conductivity electrode was no longer responding to changing chloride levels. With the results, it is believed that the simple chloride sensor could be used for continuous monitoring of groundwater quality....

  8. El efecto abanico y la paradoja del experto

    Directory of Open Access Journals (Sweden)

    Carlos J. Gómez-Ariza

    2010-09-01

    Full Text Available La investigación sobre la memoria ha demostrado que conocer más hechos sobre algo conlleva un incremento en el tiempo de reconocimiento de información al respecto (el efecto abanico. Aunque explicable por teorías de amplio espectro sobre la cognición humana, este efecto de interferencia plantea una paradoja: ¿cómo es posible entonces que un experto en un tema no sucumba ante los efectos de la interferencia durante la recuperación? La respuesta parece estar relacionada con la capacidad para integrar la información en estructuras complejas de información.

  9. Membrane chloride transport measured using a chloride-sensitive fluorescent probe

    International Nuclear Information System (INIS)

    Transport of chloride across cell membranes through exchange, cotransport, or conductive pathways is a subject of great biological importance. Current methods of measurement are restricted in their sensitivity, time resolution, and applicability. A new transport measurement technique has been developed on the basis of the fluorescence quenching by chloride of the dye 6-methoxy-N-(3-sulfopropyl)quinolinium (SPQ). SPQ fluorescence quenching by chloride is rapid and sensitive, with a greater than 50% decrease in fluorescence at 10 mM chloride. SPQ fluorescence is not altered by other physiological anions or by pH and can be used to measure both neutral and conductive transport processes. The high water solubility and membrane permeability properties of SPQ make it ideal for use in both membrane vesicles and cells. Chloride transport determined with SPQ was validated by measurement of erythrocyte chloride/anion exchange and membrane vesicle chloride conductance using 35SO4 uptake

  10. Efecto neuroprotector de los cannabinoides en las enfermedades neurodegenerativas

    OpenAIRE

    Carlos Suero-García; Lucia Martín-Banderas; Mª Ángeles Holgado

    2015-01-01

    Objetivos: Se analiza la situación actual de las investigaciones relacionadas con las sustancias cannabinoides, así como su interacción con el organismo, clasificación, efectos terapéuticos y su uso en las enfermedades neurodegenerativas. Métodos: Se realiza una exhaustiva revisión bibliográfica relacionada con las sustancias cannabinoides y sus derivados sintéticos, haciendo especial hincapié en la forma de interactuar con el organismo y los efectos que provocan dichas interacciones. Concret...

  11. Chloride Transport in Undersea Concrete Tunnel

    Directory of Open Access Journals (Sweden)

    Yuanzhu Zhang

    2016-01-01

    Full Text Available Based on water penetration in unsaturated concrete of underwater tunnel, a diffusion-advection theoretical model of chloride in undersea concrete tunnel was proposed. The basic parameters including porosity, saturated hydraulic conductivity, chloride diffusion coefficient, initial water saturation, and moisture retention function of concrete specimens with two water-binder ratios were determined through lab-scale experiments. The variation of chloride concentration with pressuring time, location, solution concentration, initial saturation, hydraulic pressure, and water-binder ratio was investigated through chloride transport tests under external water pressure. In addition, the change and distribution of chloride concentration of isothermal horizontal flow were numerically analyzed using TOUGH2 software. The results show that chloride transport in unsaturated concrete under external water pressure is a combined effect of diffusion and advection instead of diffusion. Chloride concentration increased with increasing solution concentration for diffusion and increased with an increase in water pressure and a decrease in initial saturation for advection. The dominant driving force converted with time and saturation. When predicting the service life of undersea concrete tunnel, it is suggested that advection is taken into consideration; otherwise the durability tends to be unsafe.

  12. Shelf life of unrefrigerated succinylcholine chloride injection.

    Science.gov (United States)

    Boehm, J J; Dutton, D M; Poust, R I

    1984-02-01

    The shelf life of succinylcholine chloride injection at several pH values when stored at room temperature was evaluated. Solutions containing 20 mg/ml of succinylcholine chloride were stored at 25 and 40 degrees C. The reaction was studied at pH values ranging from 3.0 to 4.5. At two-week intervals, the solutions were assayed by high-pressure liquid chromatography. The initial amount of succinylcholine chloride in all samples was 100.1 +/- 2.37% of label claim. Hydrolysis of succinylcholine chloride in unbuffered solutions followed apparent zero-order kinetics. The pH range of maximum stability was found to be from 3.75 to 4.50. Succinylcholine chloride decomposed at a considerably higher rate at 40 degrees C. Allowing for the effects of pH adjustment during manufacture and degradation during shipping, losses of 7.0% and 9.0% potency can be expected after storage at 25 degrees C for four and six weeks, respectively. Succinylcholine Chloride Injection, USP, should be stored in the refrigerator; if unbuffered succinylcholine chloride injection complying with USP pH limits must be stored at room temperature, it should not be kept for longer than four weeks. PMID:6702837

  13. Factors influencing chloride deposition in a coastal hilly area and application to chloride deposition mapping

    Directory of Open Access Journals (Sweden)

    H. Guan

    2010-05-01

    Full Text Available Chloride is commonly used as an environmental tracer for studying water flow and solute transport in the environment. It is especially useful for estimating groundwater recharge based on the commonly used chloride mass balance (CMB method. Strong spatial variability in chloride deposition in coastal areas is one difficulty encountered in appropriately applying the method. A high-resolution bulk chloride deposition map in the coastal region is thus needed. The aim of this study is to construct a chloride deposition map in the Mount Lofty Ranges (MLR, a coastal hilly area of approximately 9000 km2 spatial extent in South Australia. We examined geographic (related to coastal distance, orographic, and atmospheric factors that may influence chloride deposition, using partial correlation and regression analyses. The results indicate that coastal distance, elevation, as well as terrain aspect and slope, appear to be significant factors controlling chloride deposition in the study area. Coastal distance accounts for 70% of spatial variability in bulk chloride deposition, with elevation, terrain aspect and slope an additional 15%. The results are incorporated into a de-trended residual kriging model (ASOADeK to produce a 1 km×1 km resolution bulk chloride deposition and concentration maps. The average uncertainty of the deposition map is about 20–30% in the western MLR, and 40–50% in the eastern MLR. The maps will form a useful basis for examining catchment chloride balance for the CMB application in the study area.

  14. Chloride substitution in sodium borohydride

    Science.gov (United States)

    Ravnsbæk, Dorthe B.; Rude, Line H.; Jensen, Torben R.

    2011-07-01

    The dissolution of sodium chloride and sodium borohydride into each other resulting in formation of solid solutions of composition Na(BH 4) 1- xCl x is studied. The dissolution reaction is facilitated by two methods: ball milling or combination of ball milling and annealing at 300 °C for three days of NaBH 4-NaCl samples in molar ratios of 0.5:0.5 and 0.75:0.25. The degree of dissolution is studied by Rietveld refinement of synchrotron radiation powder X-ray diffraction (SR-PXD) data. The results show that dissolution of 10 mol% NaCl into NaBH 4, forming Na(BH 4) 0.9Cl 0.1, takes place during ball milling. A higher degree of dissolution of NaCl in NaBH 4 is obtained by annealing resulting in solid solutions containing up to 57 mol% NaCl, i.e. Na(BH 4) 0.43Cl 0.57. In addition, annealing results in dissolution of 10-20 mol% NaBH 4 into NaCl. The mechanism of the dissolution during annealing and the decomposition pathway of the solid solutions are studied by in situ SR-PXD. Furthermore, the stability upon hydrogen release and uptake were studied by Sieverts measurements.

  15. Amperometric Sensor for Detection of Chloride Ions

    OpenAIRE

    Rene Kizek; Petr Babula; Jaromir Hubalek; Vojtech Adam; Libuse Trnkova

    2008-01-01

    Chloride ion sensing is important in many fields such as clinical diagnosis, environmental monitoring and industrial applications. We have measured chloride ions at a carbon paste electrode (CPE) and at a CPE modified with solid AgNO3, a solution of AgNO3 and/or solid silver particles. Detection limits (3 S/N) for chloride ions were 100 μM, 100 μM and 10 μM for solid AgNO3, solution of AgNO3 and/or solid silver particles, respectively. The CPE modified with silver particles is the mo...

  16. Binary Nucleation of Water and Sodium Chloride

    Energy Technology Data Exchange (ETDEWEB)

    Nemec, Thomas [Institute of Thermomechanics ASCR, Prague, Czech Republic; Marsik, Frantisek [Institute of Thermomechanics ASCR, Prague, Czech Republic; Palmer, Donald [ORNL

    2005-01-01

    Nucleation processes in the binary water-sodium chloride system are investigated in the sense of the classical nucleation theory (CNT). The CNT is modified to be able to handle the electrolytic nature of the system and is employed to investigate the acceleration of the nucleation process due to the presence of sodium chloride in the steam. This phenomenon, frequently observed in the Wilson zone of steam turbines, is called early condensation. Therefore, the nucleation rates of the water-sodium chloride mixture are of key importance in the power cycle industry.

  17. Efectos del D-003 sobre patrones conductuales de roedores

    Directory of Open Access Journals (Sweden)

    Lilia Fernández Dorta

    2005-01-01

    Full Text Available El D-003 es una mezcla de ácidos alifáticos de muy alto peso molecular purificada de la cera de la caña de azúcar con efectos hipocolesterolemizante y antiagregante plaquetario demostrados experimentalmente y en estudios clínicos Fase I y II. Los estudios experimentales y clínicos culminados han mostrado que el D-003 es seguro y bien tolerado. Sin embargo, la farmacología de la seguridad de nuevos medicamentos investiga sus efectos sobre diversos sistemas que pudieran ser blancos potenciales de toxicidad. Teniendo en cuenta que los efectos adversos relacionados con el Sistema Nervioso (SN están entre los más frecuentes para diversas áreas terapéuticas, estos estudios suelen investigar los efectos de las sustancias sobre la función y estructura del SN. La investigación de los efectos sobre patrones conductuales de roedores comúnmente representa la primera etapa de estos estudios. De acuerdo con ello, el presente estudio tuvo como objetivo investigar los efectos del tratamiento oral con D-003 (dosis únicas y repetidas sobre la actividad exploratoria, la respuesta al plato caliente, la sujeción y ejecución en varilla rotatoria y la evitación pasiva de una sola prueba de aprendizaje en ratones. Los animales se distribuyeron aleatoriamente en cinco grupos experimentales (10 animales/grupo: uno control que recibió el vehículo goma acacia-H20 y cuatro tratados con D-003 (5, 25, 100 y 400 mg/kg, respectivamente. El tratamiento oral con dosis únicas y repetidas de D-003 (400 mg/kg aumentó de forma modesta, pero significativa, la actividad exploratoria con respecto al grupo control. Sin embargo, el D-003 no modificó la respuesta en el ensayo de plato caliente, la capacidad de sujeción y ejecución motora en varilla rotatoria ni la retención del aprendizaje en el ensayo de evitación pasiva. Se necesitan estudios ulteriores que diluciden las causas por las cuales el D-003 aumenta la actividad exploratoria en ratones y que

  18. Efecto del D-004 sobre patrones conductuales en roedores

    Directory of Open Access Journals (Sweden)

    Daisy Carbajal Quintana

    2007-01-01

    Full Text Available El D-004 es un extracto lipídico de los frutos de la palma real cubana (Roystonea regia que ha mostrado efectos protectores sobre la hyperplasia prostática (HP inducida en roedores con testosterona, pero no con dihidrotestosterona y que además, antagoniza respuestas mediadas por los ¿1-adrenoreceptores prostáticos. El D-004 mostró una modesta acción antiinflamatoria en el modelo de granuloma por algodón, modelo que se acerca más a la condición de inflamación crónica aparejada a la hiperplasia prostatica benigna (HPB en el hombre, lo que podría contribuir, en alguna medida, a su efecto en los modelos de HP. Teniendo en cuenta que los efectos adversos relacionados con el sistema nervioso (SN están entre los más frecuentes para diversas áreas terapéuticas, es obligado investigar los efectos de las sustancias sobre la función y estructura del SN. La investigación de los efectos sobre patrones conductuales de roedores comúnmente representa la primera etapa de estos estudios. El presente estudio investigó los efectos del tratamiento oral con D-004 (dosis únicas y repetidas sobre la actividad exploratoria, la respuesta al plato caliente y a las contracciones inducidas con ácido acético (200, 400 y 800 mg/kg, así como sobre la sujeción en varilla rotatoria y la fuerza de agarre en ratones (250, 500 y 1 000 mg/kg. El tratamiento oral con D-004 no modificó la actividad exploratoria, la respuesta al plato caliente y a las contracciones inducidas con ácido acético, así como la sujeción en varilla y la fuerza de agarre . El tratamiento oral con D-004 en el intervalo de dosis indicado no indujo efectos neurotóxicos, ya que no modificó ninguna de las conductas estudiadas.

  19. Catastrophic event modeling. [lithium thionyl chloride batteries

    Science.gov (United States)

    Frank, H. A.

    1981-01-01

    A mathematical model for the catastrophic failures (venting or explosion of the cell) in lithium thionyl chloride batteries is presented. The phenomenology of the various processes leading to cell failure is reviewed.

  20. Monoclonal antibodies to the apical chloride channel in Necturus gallbladder inhibit the chloride conductance.

    OpenAIRE

    Finn, A L; Tsai, L M; Falk, R J

    1989-01-01

    Monoclonal antibodies raised by injecting Necturus gallbladder cells into mice were tested for their ability to inhibit the apical chloride conductance induced by elevation of cellular cAMP. Five of these monoclonal antibodies bound to the apical cells, as shown by indirect immunofluorescence microscopy, and inhibited the chloride conductance; one antibody that bound only to subepithelial smooth muscle, by indirect immunofluorescence microscopy, showed no inhibition of chloride transport. The...

  1. Factors influencing chloride deposition in a coastal hilly area and application to chloride deposition mapping

    OpenAIRE

    H. Guan; Love, A. J.; C. T. Simmons; A. S. Kayaalp

    2009-01-01

    Chloride is commonly used as an environmental tracer for studying water flow and solute transport in the environment. It is especially useful for estimating groundwater recharge based on the commonly used chloride mass balance (CMB) method. Strong spatial variability in chloride deposition in coastal areas is one difficulty encountered in appropriately applying the CMB approach. Furthermore, intensive vegetation clearance for agriculture, for example during the European settlement in many...

  2. Telomerization of Vinyl Chloride with Chloroform Initiated by Ferrous Chloride-Dimethylacetamide under Ultrasonic Conditions

    Directory of Open Access Journals (Sweden)

    Hua Qian

    2015-01-01

    Full Text Available Telomerization of vinyl chloride with chloroform was investigated using ferrous chloride-dimethylacetamide system, and 42.1% yield, more than four times the one reported before, was achieved. The addition of ultrasound further improved the reaction and yield was raised to 51.9% with trace byproducts at highly reduced reaction time and temperature. Ferrous chloride-dimethylacetamide under ultrasonic irradiation acts as a very efficient catalyst system for the 1 : 1 telomerization.

  3. The kinetics of the hydrogen chloride oxidation

    Directory of Open Access Journals (Sweden)

    Gonzalez Martinez Isai

    2013-01-01

    Full Text Available Hydrogen chloride (HCl oxidation has been investigated on technical membrane electrode assemblies in a cyclone flow cell. Influence of Nafion loading, temperature and hydrogen chloride mole fraction in the gas phase has been studied. The apparent kinetic parameters like reaction order with respect to HCl, Tafel slope and activation energy have been determined from polarization data. The apparent kinetic parameters suggest that the recombination of adsorbed Cl intermediate is the rate determining step.

  4. Estimating the chloride transport in cement paste

    OpenAIRE

    Princigallo, A.

    2012-01-01

    A method was developed to measure the diffusion coefficient of chloride ions in cement paste based on an analytical solution to Fick’s 2nd law in a cylindrical coordinate system. This natural method yielded diffusivity results within as little as a month. Testing time was reduced by exploiting the three-dimensional inward flux in the specimen. In an attempt to determine the saturation concentration, dense portland cement pastes were exposed to a concentrated chloride solution. The method prov...

  5. The humic matter as natural inhibitor of CaCO{sub 3} in cooling water system; Las sustancias humicas como inhibidores naturales del CaCO{sub 3}, en sistemas de enfriamiento

    Energy Technology Data Exchange (ETDEWEB)

    Celada Murillo, Ana Teresa [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico)

    2000-07-01

    precipitacion se adicionan al agua de circulacion H{sub 2}SO{sub 4} e inhibidores de precipitacion que contienen polifosfatos (entre los mas utilizados). Estos quimicos traen consigo un impacto ambiental al estar asociados con problemas de eutroficacion de cuerpos de agua. Con el fin de contribuir a la disminucion del uso de aditivos contaminantes, esta investigacion propone la utilizacion de sustancias humicas (SH) como inhibidores naturales de la precipitacion del CaCO{sub 3}. Las SH son moleculas organicas de estructura quimica compleja, presentes en el agua y suelos por la degradacion de plantas y animales muertos, participan en reacciones de complejacion, intercambio ionico y adsorcion con iones metalicos. La inhibicion del CaCO{sub 3} por SH, se observo en soluciones sinteticas y de agua natural (pozo, rio y agua residual tratada), las cuales tenian concentraciones de calcio y alcalinidad tipicas del agua de repuesto y circulacion de sistemas de enfriamiento de centrales termoelectricas. En estas soluciones se indujo la precipitacion del CaCO{sub 3} por la adicion de NaOH 0.1 N en forma continua (metodo del pH critico), en ausencia y presencia de SH. En cada experimento, se registro el tiempo y volumen de hidroxido de sodio agregado para que la precipitacion de CaCO{sub 3} se presentara. La inhibicion de la precipitacion del CaCO{sub 3} por SH, fue evidente por el aumento en el tiempo de inicio de la precipitacion de esta sal. En las soluciones sinteticas este tiempo se incremento entre 30 y 40% y en las de agua natural (pozo) las SH inhibieron la precipitacion del CaCO{sub 3} durante 120 minutos.

  6. Effect of Chloride Type on Penetration of Chloride Ions in Concrete

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The influence of chloride type on the diffusivity of chloride ions in concrete was studied by experiment. The result shows that the glectric resistance of concrete and the chloride diffusion coefficient are influenced by chloride type. For the same water/cement ratio (W/C), the diffusion coefficient D in KCl solution is larger than that in NaCl solution; however, the concrete resistance in KCl solution is smaller than that in NaCl solution. The experimental result is analyzed with theory of diffusion.

  7. Uso de inhibidores de quinasas para la elaboración de composiciones farmacéuticas para el tratamiento de la enfermedad de Parkinson, composiciones farmacéuticas y procedimiento de diagnóstico de enfermedad de Parkinson

    OpenAIRE

    Navarro Hilfiker, Sabine; Rubio de la Torre, Elena

    2008-01-01

    [ES] La presente invención describe la relación directa entre la fosforilación de a proteína parkina y la formación de agregados intracelulares en neuronas. Así, inhibidores de la caseína quinasa I y Cdk5 pueden ser útiles compuestos farmacéuticos para el tratamiento de enfermedades asociadas a cuerpos de Lewy, como son la enfermedad de Parkinson y la demencia de cuerpos de Lewy. Por otro lado, la identificación de parking fosforilada en muestras biológicas del sistema nervioso central, prefe...

  8. ¿Qué debemos conocer de los inhibidores de bomba protones, para su uso en las unidades de dolor? What need to know the Proton Pump Inhibitors to use in the chronic pain clinic?

    Directory of Open Access Journals (Sweden)

    J. A. García-García

    2007-10-01

    Full Text Available Los inhibidores de la bomba de protones (IBP son fármacos útiles para el control de la patología asociada con la acidez gástrica, patología con una alta prevalencia dentro de la población general. En las Unidades de dolor tratamos pacientes con pluripatología y polimedicados, entre ellas patologías asociadas con la acidez gástrica. Así como también utilizamos fármacos como AINES, glucocorticoides, bifosfonatos... que pueden reactivar, empeorar la patología ligada a la acidez. El conocimiento de los aspectos farmacológicos de los IBP, tanto farmacocinéticos como farmacodinámicos, es necesario y preciso para poder elegir el más adecuado para nuestros pacientes con pluripatologia y polimedicados evitando las posibles interacciones farmacológicas que podrían afectar al estado de salud de nuestros pacientes.Protón Pump Inhibitors (PPIs have shown their usefulness in the treatment of acid-related disorders, highly prevalent in normal population. Pain units are used to treating patients with a wide range of diseases, including acid related-disorders, who are also being prescribed many different drugs, like NSAIDs, corticosteroids or biphosponates, which may reactívate or even worsen acid-related disorders. Knowledge of the pharmacological aspects of PPIs, both their pharmacokinetics and pharmacodynamics, is needed to properly choose the one which fits most to our multi-pathologic, multi-treated patients, in order to avoid possible pharmacological interactions than could endanger their health condition.

  9. Inhibidores de bomba de protones y clopidogrel: Evidencia de interacción farmacológica de gran impacto clínico Proton pump inhibitors and clopidogrel: Evidence of a Pharmacological interaction of great clinical impact

    Directory of Open Access Journals (Sweden)

    Ingrid Martínez

    Full Text Available Clopidogrel, una tienopiridina, es un antiagregante plaquetario que en la actualidad constituye la piedra angular del tratamiento médico en pacientes que presentan eventos coronarios agudos. Es una prodroga que debe ser convertida en la forma activa a nivel hepático, por la isoenzima CYP2C19. Recientemente, se ha llamado ampliamente la atención sobre la probable interacción entre los inhibidores de la bomba de protones y el clopidogrel por la inhibición competitiva que estos hacen sobre el sistema enzimático hepático activador de clopidogrel, que causa disminución de la eficacia del mismo como antitrombótico. Sin embargo, la evidencia sobre esta interacción es contradictoria y hasta el momento no se han realizado ensayos clínicos para resolver esta duda. Si se necesita utilizar un IBP en pacientes que utilizan clopidogrel, se recomienda el pantoprazol o el esomeprazol por la mínima inhibición que ejercen sobre el CYP2C19.Clopidogrel, a thienopyridine, is an antiplatelet drug which currently represents the cornerstone for the treatment of acute coronary events. It is a pro-drug that must be converted at hepatic level into its active form by the CYP2C19 isoenzyme. Recently the interaction between proton pump inhibitors and clopidogrel has been widely brought to attention. The competitive inhibition that these generate on the hepatic enzymatic system probably activates clopidogrel, thus causing a decrease in its effectiveness as an antithrombotic. Nevertheless, evidence is contradictory, and until now no clinical trials have been performed to clear up doubts. If a PPI is to be used on patients who take clopidogrel, the use of Pantoprazole or Esomeprazole is recommended because they exert minimal inhibition on CYP2C19.

  10. Antifungal activity of essential oils when associated with sodium chloride or fatty acids

    Directory of Open Access Journals (Sweden)

    Tantatoui-Elaraki, Abdelthafour

    1994-12-01

    Full Text Available The inhibition of mycelium growth in a Zygorhynchus sp. and an Aspergillus niger isolates was studied. The inhibition rates (IR caused by 4 essential oils (EO, 5 fatty acids and sodium chloride at various concentrations were determined in Sabouraud Dextrose Agar.
    A synergy of action was observed between sodium chloride at 7.5% and the EO of thyme (0.04%, camomile (0.4% and mugwort (0.2 and 0.1% on A. niger and between sodium chloride (5% and the EO of camomile (0.1% and mugwort (0.1 and 0.01% and sodium chloride (7.5% and eucalyptus EO (0.4 and 0.2% on Zygorhynchus sp.
    Camomile EO (0.13% associated with propionic acid (0.075%, lauric acid (0.05% or oleic acid (0.15% led to synergetic effect on Zygorhynchus sp. as well as thyme EO (0.04 and 0.05%, respectively with propionic acid (0.1% and linolenic acid (0.075% on A. niger. Other combinations exerted no higher effects than each of the substances used alone.
    Practical applications of the results observed were discussed

    Se ha estudiado la inhibición del crecimiento miceliar en un aislamiento de Zygorhynchus sp. y otro de Aspergillus niger. Se determinaron las tasas (o índices de inhibición (IR en Agar Sabouraud Dextrosa provocados por varias concentraciones de 4 aceites esenciales (EG, 5 ácidos grasos y cloruro sódico.
    Se observó un efecto sinérgico entre cloruro sódico al 7.5% y los aceites esenciales de tomillo (0.04%, manzanilla (0.4% y artemisa (0.2 y 0.1% sobre A. niger, y entre cloruro sódico (5% y los aceites esenciales de manzanilla (0.1% y de artemisa (0.1 y 0.01%, así como cloruro sódico (7.5% y aceite esencial de eucalipto (0.4 y 0.2%, sobre Zygorhynchus sp.
    El aceite esencial de manzanilla (0.13% en asociación con ácido propiónico (0.075%, ácido láurico (0.05% o ácido oleico (0.15% provocó un efecto sinérgico sobre Zygorhynchus sp., de la misma forma

  11. 49 CFR 179.102-17 - Hydrogen chloride, refrigerated liquid.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Hydrogen chloride, refrigerated liquid. 179.102-17...) § 179.102-17 Hydrogen chloride, refrigerated liquid. Each tank car used to transport hydrogen chloride... on or after March 16, 2009 used for the transportation of hydrogen chloride, refrigerated...

  12. 21 CFR 178.3290 - Chromic chloride complexes.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Chromic chloride complexes. 178.3290 Section 178... SANITIZERS Certain Adjuvants and Production Aids § 178.3290 Chromic chloride complexes. Myristo chromic chloride complex and stearato chromic chloride complex may be safely used as release agents in the...

  13. Efecto in vitro de olomoucina en el ciclo celular de linfocitos humanos

    OpenAIRE

    Camargo M.; López C.

    2001-01-01

    La olomoucina, un derivado de purina relacionado con el ATP, ha sido reportado como uneficiente inhibidor del ciclo celular de células animales y vegetales, debido a su alta especificidadpor las ciclinas dependientes de kinasa (CDK) CDK1 y CDK2, su capacidad radica en inhibir elciclo celular en las transiciones G2/M y G1/S respectivamente. Con el objetivo de explorar lapotencial aplicación de la olomoucina en el análisis citogenético de alta resolución y estudiosde proliferación celular en cu...

  14. Factors influencing chloride deposition in a coastal hilly area and application to chloride deposition mapping

    Directory of Open Access Journals (Sweden)

    H. Guan

    2009-09-01

    Full Text Available Chloride is commonly used as an environmental tracer for studying water flow and solute transport in the environment. It is especially useful for estimating groundwater recharge based on the commonly used chloride mass balance (CMB method. Strong spatial variability in chloride deposition in coastal areas is one difficulty encountered in appropriately applying the CMB approach. Furthermore, intensive vegetation clearance for agriculture, for example during the European settlement in many coastal areas of Australia, may have perturbed catchment chloride balance conditions for appropriate use in CMB applications. In order to deal with these issues, a high resolution chloride deposition map in the coastal region is needed. In this study, we examined geographic, orographic, and atmospheric factors influencing chloride deposition in the Mount Lofty Ranges (MLR, a coastal hilly area of approximately 9000 km2 spatial extent in South Australia, using partial correlation and regression analyses. The results indicate that coastal distance, and terrain aspect and slope are two most significant factors controlling chloride deposition. Coastal distance accounts for 65% spatial variability in chloride deposition, with terrain aspect and slope for 8%. The deposition gradient is about 0.08 gm-2 year-1 km-1 as one progresses inland. The results are incorporated into a published de-trended residual kriging approach (ASOADeK to produce a 1 km×1 km resolution annual chloride deposition map and a bulk precipitation chloride concentration map. The average uncertainty of the deposition map is about 30% in the western MLR, and over 50% in the eastern MLR. The maps will form a very useful basis for examining catchment chloride balances for use in the CMB application in the study area.

  15. Efecto diferencial de fluoxetina en psicopatología de personalidad límite Differential effect of fluoxetine on psychopathology of borderline personality disorders

    Directory of Open Access Journals (Sweden)

    Hernán Silva

    2003-10-01

    Full Text Available Introducción. Tanto la depresión como la impulsividad han sido asociadas a disfunciones del sistema serotoninérgico y ambas responden al tratamiento con inhibidores selectivos de la recaptura de serotonina. En este trabajo se estudia el efecto diferencial de fluoxetina sobre la impulsividad y los síntomas depresivos en pacientes con trastorno límite de personalidad. Sujetos y método. A 38 pacientes con trastorno límite de personalidad y sin patología del Eje I, se les administró fluoxetina en dosis flexibles por siete semanas. Fueron evaluados semanalmente mediante BPRS, GAF, escala de depresión de Hamilton y una escala de impulsividad. Se estudió la variación temporal del puntaje de estas escalas en dos grupos de pacientes: uno con elevada impulsividad y otro con baja impulsividad. Resultados. Hubo una mejoría de la sintomatología global y de los síntomas depresivos y la impulsividad en el grupo total de pacientes. En el grupo de sujetos más impulsivo hubo una mayor reducción de la impulsividad en las dos primeras semanas de tratamiento. En cambio, en los pacientes menos impulsivos hubo una mayor reducción de los síntomas depresivos a partir de la tercera semana de tratamiento. Ambas diferencias fueron estadísticamente significativas. Conclusiones. La fluoxetina tuvo un efecto diferencial sobre los síntomas depresivos y la impulsividad en los pacientes con trastorno límite de personalidad estudiados. Estos resultados concuerdan con los de otros autores y sugieren que los ISRS actúan por diferentes mecanismos neurobiológicos en ambos tipos de síntomas.Introduction. Depression and impulsivity has been associated to a dysfunction of serotonergic system and are treated with serotonin reuptake inhibitors (SSRI. In this work we study differential effects of fluoxetine on impulsivity and depressive symptoms in borderline personality disorders patients. Subjects and method. 38 borderline personality disorders patients without

  16. Inhibition of nitrite-induced toxicity in channel catfish by calcium chloride and sodium chloride

    Science.gov (United States)

    Tommasso J.R., Wright, M. I.; Simco, B.A.; Davis, K.B.

    1980-01-01

    Environmental chloride has been shown to inhibit methemoglobin formation in fish, thereby offering a protective effect against nitrite toxicity. Channel catfish (Ictalurus punctatus) were simultaneously exposed to various environmental nitrite and chloride levels (as either CaCl2 or NaCl) in dechlorinated tap water (40 mg/L total hardness, 47 mg/L alkalinity, 4 mg/L chloride, pH = 6.9-7.1, and temperature 21-24°C). Methemoglobin levels in fish simultaneously exposed to 2.5 mg/L nitrite and up to 30 mg/L chloride as either CaCl2 or NaCl were similar but significantly lower than in unprotected fish. Exposure to 10 mg/L nitrite and 60 mg/L chloride resulted in methemoglobin levels similar to those of the controls; most unprotected fish died. Fish exposed to 10 mg/L nitrite had significantly lower methemoglobin levels when protected with 15.0 mg/L chloride as CaCl2 than with NaCl. Fish exposed to nitrite in the presence of 60 mg/L chloride (as either CaCl2 or NaCl) had similar 24-h LC50 values that were significantly elevated above those obtained in the absence of chloride. Calcium had little effect on tolerance to nitrite toxicity in channel catfish in contrast to its large effect reported in steelhead trout (Salmo gairdneri).

  17. Amine and Titanium (IV Chloride, Boron (III Chloride or Zirconium (IV Chloride-Promoted Baylis-Hillman Reactions

    Directory of Open Access Journals (Sweden)

    Shi-Cong Cui

    2001-10-01

    Full Text Available The Baylis-Hillman reactions of various aryl aldehydes with methyl vinyl ketone at temperatures below -20oC using Lewis acids such as titanium (IV chloride, boron (III chloride or zirconium (IV chloride in the presence of a catalytic amount of selected amines used as a Lewis bases afford the chlorinated compounds 1 as the major product in very high yields. Acrylonitrile can also undergo the same reaction to give the corresponding chlorinated product in moderate yield. A plausible reaction mechanism is proposed. However, if the reaction was carried out at room temperature (ca. 20oC, then the Z-configuration of the elimination product 3, derived from 1, was formed as the major product.

  18. Hydrolysis of ferric chloride in solution

    International Nuclear Information System (INIS)

    The Detox trademark process uses concentrated ferric chloride and small amounts of catalysts to oxidize organic compounds. It is under consideration for oxidizing transuranic organic wastes. Although the solution is reused extensively, at some point it will reach the acceptable limit of radioactivity or maximum solubility of the radioisotopes. This solution could be cemented, but the volume would be increased substantially because of the poor compatibility of chlorides and cement. A process has been developed that recovers the chloride ions as HCl and either minimizes the volume of radioactive waste or permits recycling of the radioactive chlorides. The process involves a two-step hydrolysis at atmospheric pressure, or preferably under a slight vacuum, and relatively low temperature, about 200 degrees C. During the first step of the process, hydrolysis occurs according to the reaction below: FeCl3liquid + H2O → FeOClsolid + 2 HClgas During the second step, the hot, solid, iron oxychloride is sprayed with water or placed in contact with steam, and hydrolysis proceeds to the iron oxide according to the following reaction: 2 FeOClsolid + H2O → Fe2O3solid + 2 HClgas. The iron oxide, which contains radioisotopes, can then be disposed of by cementation or encapsulation. Alternately, these chlorides can be washed off of the solids and can then either be recycled or disposed of in some other way

  19. Chloride equilibrium potential in salamander cones

    Directory of Open Access Journals (Sweden)

    Bryson Eric J

    2004-12-01

    Full Text Available Abstract Background GABAergic inhibition and effects of intracellular chloride ions on calcium channel activity have been proposed to regulate neurotransmission from photoreceptors. To assess the impact of these and other chloride-dependent mechanisms on release from cones, the chloride equilibrium potential (ECl was determined in red-sensitive, large single cones from the tiger salamander retinal slice. Results Whole cell recordings were done using gramicidin perforated patch techniques to maintain endogenous Cl- levels. Membrane potentials were corrected for liquid junction potentials. Cone resting potentials were found to average -46 mV. To measure ECl, we applied long depolarizing steps to activate the calcium-activated chloride current (ICl(Ca and then determined the reversal potential for the current component that was inhibited by the Cl- channel blocker, niflumic acid. With this method, ECl was found to average -46 mV. In a complementary approach, we used a Cl-sensitive dye, MEQ, to measure the Cl- flux produced by depolarization with elevated concentrations of K+. The membrane potentials produced by the various high K+ solutions were measured in separate current clamp experiments. Consistent with electrophysiological experiments, MEQ fluorescence measurements indicated that ECl was below -36 mV. Conclusions The results of this study indicate that ECl is close to the dark resting potential. This will minimize the impact of chloride-dependent presynaptic mechanisms in cone terminals involving GABAa receptors, glutamate transporters and ICl(Ca.

  20. Efecto de la Escolaridad sobre la Fecundidad en Nicaragua

    Directory of Open Access Journals (Sweden)

    Bonilla, Roger

    2006-07-01

    Full Text Available Son muchos los estudios que han mostrado la asociación inversa existente entre la escolaridad y la fecundidad. El objetivo de este estudio fue cuantificar el efecto de la escolaridad sobre la fecundidad, en una muestra de 11246 mujeres de Nicaragua. Se ajustaron modelos de regresión de Poisson en donde la variable respuesta Y fue el número de hijos nacidos vivos de la mujer y la variable independiente fue la escolaridad, controlando por otros efectos como zona de residencia, tenencia de empleo, uso actual de métodos anticonceptivos, edad y una medida del nivel informativo de la mujer. Los modelos propuestos son significativos (p < 0.05 el hecho de tener escolaridad primaria hace que el riesgo de tener hijos adicionales sea 13% menor con respecto a las mujeres que no tienen escolaridad alguna. El riesgo para las mujeres con escolaridad secundaria es 40% menor (Modelo 1. El efecto interactivo de la escolaridad secundaria y más y la edad es significativo ( <0.05 (Modelo 2. El estudio suministra información útil para el apropiado diseño de políticas públicas y programas educativos.

  1. Combining sulfate electrowinning with chloride leaching

    Science.gov (United States)

    Fletcher, A. W.; Sudderth, R. B.; Olafson, S. M.

    1991-08-01

    Although the chloride leaching of copper sulfide concentrates has proved highly efficient, electrowinning from chloride solutions presents many difficulties, notably in cell design and the handling of the powder product. Sulfate electrowinning,on the other hand, continues to improve and has played a significant part in the widespread adoption of the solvent extraction-electrowinning process for copper recovery from low-grade ores. It has been found that the two steps can be combined by introducing a novel solvent extraction process after chloride leaching. This article presents the results of laboratory tests to prove the feasibility of this approach and discusses how it can be integrated into a commercially viable flow sheet.

  2. EVALUATION OF GENERICINHIBITORS BEHAVIOR FORMULTIPHASE SYSTEMS (STEEL-BRINE-CO2/H2S BYUSING ELECTROCHEMICAL TECHNIQUES Evaluación del compotamiento de inhibidores genéricos para sistemas multifásicos (acero-salmuera-CO2/H2S por medio de técnicas electroquímicas

    Directory of Open Access Journals (Sweden)

    Darío-Yesid Peña B

    2007-12-01

    Full Text Available One of the main ways to inhibit the corrosion is the adsorption of organic compounds on the surface of a metal. This study reports the behavior of six different organic inhibitors in a system carbon steel AISI-SAE1020/brine 3%w of NaCl/ gas mixture of 6% volume of CO2/10 ppm of H2S/ hydrocarbon. Two primary amines with sixteen and eighteen atoms of carbon were used, a secondary amine with twenty atoms and three carboxylic acids of sixteen, eighteen and twenty carbon atoms. Linear polarization resistance measurements were used, along with Tafel extrapolation and electrochemical impedances to assess the influence of temperature, velocity of fluid, inhibitor concentration and concentration of oleic phase on the inhibition efficiency in the Electrode of Rotational Cylinder, ECR. Activation and adsorption energies were calculated for the processes of corrosion in the system; according to the values derived, it was possible to define the system brine/CO2/H2S/ inhibitor, as a process with mixed control, where the phenomenon of mass transfer and that of charge transfer are in competition and the values obtained for the energy of adsorption of Gibbs, allowed checking that these compounds showed a chemical adsorption on the metallic surface. Under critical testing conditions (4 m/s, 59ºC or 332,15K the amines present a better efficiency than carboxylic acids, thus complying with the electro-negativity theory applied to inhibitors. It was then possible to establish by the results obtained for the with hydrocarbon cuts tests, that this parameter adversely affects the percentage efficiency of the inhibitor.Uno de los principales caminos para la inhibición de la corrosión lo constituye la adsorción de compuestos orgánicos sobre la superficie de un metal. En este estudio se reporta el comportamiento de seis diferentes inhibidores orgánicos en un sistema acero al carbono AISI-SAE 1020/Salmuera al 3%w de NaCl/ mezcla gaseosa de 6% volumen de CO2/10 ppm de

  3. El lado oscuro de las organizaciones: efectos negativos en el factor humano

    OpenAIRE

    Juana Patlán Pérez; Dolores Margarita Navarrete Zorrilla; María del Rosario García Velázquez

    2010-01-01

    El presente trabajo tiene como propósito determinar qué es el lado oscuro de las organizaciones y analizar cuáles son los efectos negativos que producen las organizaciones en el factor humano. Para tal propósito se efectuó una revisión a la literatura. El análisis de los efectos negativos que producen las organizaciones se realiza desde una perspectiva sistémica que sustenta que dichos efectos van desde provocar efectos derivados del trabajo tales como accidentes, enfermedades del trabajo, ha...

  4. Effect of distance from sea on chloride aggressiveness in concrete structures in brazilian coastal site

    Directory of Open Access Journals (Sweden)

    Meira, G. R.

    2003-12-01

    Full Text Available The distance of concrete structures from the sea is an important aspect when studying the deleterious effect of airborne salinity in marine environment zone. It permits to know how the durability of structures is affected by increasing the distance from the sea. This paper presents results of an experimental work on assessing the effect of the distance from sea on chloride aggressiveness, considering both the airborne salinity and chloride content in concrete specimens located at different distances from sea. This study has been carried out at Joao Pessoa, capital of the State of Paraiba, located in the northeast part of Brazil. The results indicated a drastic reduction of chloride deposition from marine aerosol, especially along the first 200 meters from the sea. Similar behavior was observed in the concrete specimens, even though the reduction has been less pronounced. Although more research is necessary, the differences in the rates of chloride decrease may be explained by different reasons, including the different chloride concentration in air and on concrete surface, the phenomena related to the skin effect and surface washing by rain.

    La influencia de la distancia al mar es un tema clave en el estudio de la agresividad salina en zona de atmósfera marina, ya que permite conocer cómo afecta a la durabilidad de las construcciones cuando aumenta la distancia al mar. Este trabajo presenta resultados de un estudio experimental que valora la situación a través de la medida del depósito de cloruros de la niebla salina y en probetas de hormigón expuestas a distintas distancias desde el mar en la ciudad de Joâo Pessoa, ubicada en la costa noreste de Brasil. Los resultados indican una importante disminución del depósito de cloruros de la niebla salina a medida que se aumenta la distancia al mar, especialmente en los primeros doscientos metros. La concentración de cloruros en el hormigón indica un comportamiento semejante. Sin

  5. Efecto neuroprotector de los cannabinoides en las enfermedades neurodegenerativas

    Directory of Open Access Journals (Sweden)

    Carlos Suero-García

    2015-01-01

    Full Text Available Objetivos: Se analiza la situación actual de las investigaciones relacionadas con las sustancias cannabinoides, así como su interacción con el organismo, clasificación, efectos terapéuticos y su uso en las enfermedades neurodegenerativas. Métodos: Se realiza una exhaustiva revisión bibliográfica relacionada con las sustancias cannabinoides y sus derivados sintéticos, haciendo especial hincapié en la forma de interactuar con el organismo y los efectos que provocan dichas interacciones. Concretamente, se estudiarán sus efectos neuroantiinflamatorio y analgésico lo que conlleva al efecto neuroprotector en enfermedades neurodegenerativas tales como Alzheimer, Parkinson, Huntington, esclerosis múltiple y esclerosis lateral amiotrófica. Resultados: Desde hace miles de años la planta Cannabis Sativa ha sido utilizada por muchas culturas con distintos fines, de ocio, textiles, analgésicos, pero no es hasta finales del siglo XX cuando se empieza a incentivar los estudios científicos relacionados con ésta. La planta posee una mezcla de unos 400 componentes, de los cuales 60 pertenecen al grupo de los cannabinoides siendo los principales el cannabinol, cannabidiol y tetrahidrocannabinol. Con el descubrimiento de las sustancias cannabinoides, sus derivados, y los receptores que interactúan, se amplían las posibilidades terapéuticas teniendo un especial interés el efecto neuroprotector que estas sustancias contienen. Conclusiones. Se ha demostrado el gran potencial de los cannabinoides como sustancias terapéuticas más allá de su uso analgésico o antiemético, esto es, en enfermedades neurodegenerativas en las que pueden no solo disminuir los síntomas, sino frenar el proceso de la enfermedad. Otra posible aplicación puede ser en el campo oncológico, siendo particularmente intensa la actividad investigadora realizada en los últimos 15 años.

  6. Alkali metal and ammonium chlorides in water and heavy water (binary systems)

    CERN Document Server

    Cohen-Adad, R

    1991-01-01

    This volume surveys the data available in the literature for solid-fluid solubility equilibria plus selected solid-liquid-vapour equilibria, for binary systems containing alkali and ammonium chlorides in water or heavy water. Solubilities covered are lithium chloride, sodium chloride, potassium chloride, rubidium chloride, caesium chloride and ammonium chloride in water and heavy water.

  7. Hydrogenation of Tasmanian alginite in the presence of tin (II) chloride and zinc chloride

    Energy Technology Data Exchange (ETDEWEB)

    Russell, N.J.

    1981-10-01

    A Mersey River (Tasmanian) algnite concentrate was heated (3 Cmin$SUP$-$SUP$1 to temperatures of 200-480 C in a small capacity, high-pressure, single-cell differential thermal analysis, batch autoclave under nitrogen or hydrogen (initial pressure 9.8 MPa) with or without 10 wt% zinc chloride or tin (II) chloride. An organic solvent (vehicle) was not used in these experiments. Although there is an almost complete conversion of alginite to gaseous and liquid products between 425 and 450 C, the compositions of the autoclave gas samples, the yields and compositions of the hexane-soluble material derived from the autoclave products, and the optical properties of the hexane-soluble residues, reflect the experimental conditions, in particular the influence of the metal chlorides. Principal phases of hydrogen uptake by alginite occur at different temperatures in a hydrogen atmosphere depending on the presence and nature of the metal chloride. The autoclave gas compositions reveal a clear distinction between the uncatalysed and catalysed experiments. The hydrocarbon gas ratios permit a distinction to be made between catalytic (carbonium ion mechanism) reactions and thermal (free radical mechanism) reactions; at higher temperatures the latter are dominant, even in the catalysed experiments. The metal chlorides lower the organic sulphur and nitrogen contents of the hexane-soluble material; zinc chloride being more effective than tin (II) chloride. Incident light fluorescence microscopy suggests that zinc chloride and tin (II) chloride give rise to different hydrogenation reactions between 300 and 425 C. Incident light fluorescence microscopy is a most useful method of studying the petrography of alignite in the hexane-insoluble residues. (28 refs.)

  8. Glucogeno sintasa en helmintos parasitos: inhibicion por benzimidazoles

    OpenAIRE

    H. Gomez-Banqueri; M. A. Garcia Ruiz; M. Monteoliva; Sanchez-Moreno, M.

    1987-01-01

    Se ha determinado el effecto inhibidor sobre la actividad Glucogeno sintetasa (E.C.2.41.11) por parte de cuatro antihelminticos: Albendazol, Mebendazol, Parbendazol y Tiabendazol. Observandose que en todos los casos, es el Parbendazol quien ha demostrado un mayor poder inhibidor sobre la glucógeno sintetasa de Ascaris suum, Fasciola hepatica y Moniezia expansa. El Tiabendazol es el anti-helmintico que menor efecto inhibidor ha presentado sobre la enzima en los tres parasitos objeto de nuestro...

  9. Combinación de metformina frente a inhibidores de la dipeptidilpeptidasa y sulfonilureas en el tratamiento de la diabetes tipo 2: impacto clínico y económico

    Directory of Open Access Journals (Sweden)

    Antoni Sicras-Mainar

    2014-12-01

    Full Text Available Objetivos. Determinar las repercusiones clínicas: adherencia, control metabólico, hipoglucemias y eventos cardiovasculares (ECV y económicas (recursos y costes de la combinación de metformina frente a IDPP4 (inhibidores dipeptidil-peptidasa-4 y sulfonilureas en pacientes con diabetes tipo 2. Materiales y métodos. Diseño observacional-multicéntrico de carácter retrospectivo. Se evaluaron pacientes ≥ 30 años, en tratamiento con metformina y que iniciaron un segundo tratamiento antidiabético oral durante 2008-2009. Se establecieron 2 grupos de estudio: a metformina+IDPP4 y b metformina+sulfonilureas. Principales medidas: comorbilidad, control metabólico (HbA1c<7%, cumplimiento y complicaciones (hipoglucemias, ECV. El seguimiento se realizó durante 2 años. El modelo de costes diferenció los costes sanitarios directos (atención primaria/especializada e indirectos (productividad laboral. Análisis estadístico: modelos de regresión logística y ANCOVA. Resultados. Se reclutaron 1405 pacientes (edad-media: 67,1 años; varones: 56,2%. Un 37,0% iniciaron un segundo tratamiento con IDPP4 y un 63,0% con sulfonilureas. A los dos años de seguimiento, los pacientes tratados con IDPP4 mostraron un mayor cumplimiento terapéutico (70,3% vs. 60,6%; p<0,001; mejor control-metabólico (64,3% vs. 60,6%; p<0,001 y menor proporción de hipoglucemias (13,9% vs. 40,4%; p<0,001, respectivamente. El promedio/unitario de los costes totales corregidos fue de 2341 € vs. 2512 €; p=0,038. Las tasas de ECV e insuficiencia renal fueron del 3,7% vs. 6,4%; p=0,027. La vildagliptina fue el fármaco más utilizado entre los IDPP4. Conclusiones. Las sulfonilureas fueron los fármacos más utilizados para el tratamiento de la diabetes. Los pacientes en tratamiento con IDPP4 presentaron mayor cumplimiento y control de la diabetes, con menores tasas de hipoglucemias y ECV, ocasionando menores costes sanitarios.

  10. Method for preparation of melts of alkali metal chlorides with highly volatile polyvalent metal chlorides

    International Nuclear Information System (INIS)

    A method for production of alkali metal (Cs, Rb, K) chloride melts with highly volatile polyvalent metal chlorides is suggested. The method consists, in saturation of alkali metal chlorides, preheated to the melting point, by volatile component vapours (titanium tetrachloride, molybdenum or tantalum pentachloride) in proportion, corresponding to the composition reguired. The saturation is realized in an evacuated vessel with two heating areas for 1-1.5 h. After gradual levelling of temperature in both areas the product is rapidly cooled. 1 fig.; 1 tab

  11. Inibidor da ECA e concentrações do peptídeo natriurético do tipo B, em idosos com insuficiência cardíaca Inhibidor de la enzima conversora de la angiotensina y concentraciones del péptido natriurético de tipo B, en personas adultas mayores con insuficiencia cardiaca ACE inhibitors and plasma B-type natriuretic peptide levels in elderly patients with heart failure

    Directory of Open Access Journals (Sweden)

    Felicio Savioli Neto

    2009-05-01

    Full Text Available FUNDAMENTO: Ensaios clínicos demonstraram os benefícios dos inibidores da ECA (IECA na atividade neuro-hormonal e na capacidade funcional de pacientes com insuficiência cardíaca (IC, com a magnitude desses efeitos sendo proporcional à dose desses agentes. Entretanto, a sistemática exclusão dos idosos, observada na maioria desses estudos, tem questionado a validação e incorporação de tais resultados na população geriátrica. OBJETIVO: Avaliar os efeitos de diferentes doses de quinapril, um IECA com meia vida biológica >24 horas, nas concentrações plasmáticas do PNB, nas distâncias percorridas no teste da caminhada de 6 minutos (TC-6 min e na incidência de reações adversas, em idosos com IC sistólica. MÉTODOS: Foram avaliados 30 pacientes (76,1 ± 5,3 anos; 15 mulheres, IC II-III (NYHA, FE ventricular esquerda FUNDAMENTO: Ensayos clínicos revelaron los beneficios de los inhibidores de la enzima conversora de la angiotensina (IECA en la actividad neurohormonal y en la capacidad funcional de pacientes con insuficiencia cardiaca (IC. La magnitud de esos efectos fue proporcional a la dosificación de esos agentes. Sin embargo, la sistemática exclusión de las personas adultas mayores, observada en la mayoría de esos estudios, ha conllevado al cuestionamiento de la validación e incorporación de dichos resultados en la población geriátrica. OBJETIVO: Evaluar los efectos de diferentes dosis de quinapril, un IECA con vida media biológica >24 horas, en las concentraciones plasmáticas del péptido natriurético de tipo B (PNB, en las distancias recorridas en el test de marcha de 6 minutos (TM6m y en la incidencia de reacciones adversas, en personas adultas mayores con IC sistólica. MÉTODOS: Se evaluaron a 30 pacientes (76,1 ± 5,3 años; 15 mujeres, IC II-III (NYHA, fracción de eyección (FE ventricular izquierda BACKGROUND: Clinical trials have demonstrated the benefits of ACE inhibitors (ACEI in the neurohormonal

  12. Oral cadmium chloride intoxication in mice

    DEFF Research Database (Denmark)

    Andersen, O; Nielsen, J B; Svendsen, P

    1988-01-01

    Diethyldithiocarbamate (DDC) is known to alleviate acute toxicity due to injection of cadmium salts. However, when cadmium chloride was administered by the oral route, DDC enhanced rather than alleviated the acute toxicity; both oral and intraperitoneal (i.p.) administration of DDC had this effec...

  13. Liquid crystalline critical dynamics in decylammonium chloride

    CERN Document Server

    Lee, K W; Lee, C E; Kang, K H; Rhee, C; Kang, J K

    1999-01-01

    Collective chain dynamics and phase transitions in a model biomembrane, decylammonium chloride (C sub 1 sub 0 H sub 2 sub 1 NH sub 3 Cl), were studied by means of proton nuclear magnetic resonance. Our measurements sensitively reflect the critical dynamics associated with the smectic C to smectic A transition of the lipid bilayer.

  14. Liquid crystalline critical dynamics in decylammonium chloride

    International Nuclear Information System (INIS)

    Collective chain dynamics and phase transitions in a model biomembrane, decylammonium chloride (C10H21NH3Cl), were studied by means of proton nuclear magnetic resonance. Our measurements sensitively reflect the critical dynamics associated with the smectic C to smectic A transition of the lipid bilayer

  15. Chloride diffusion in partially saturated cementitious material

    DEFF Research Database (Denmark)

    Nielsen, Erik Pram; Geiker, Mette Rica

    2003-01-01

    The paper proposes a combined application of composite theory and Powers' model for microstructural development for the estimation of the diffusion coefficient as a function of the moisture content of a defect-free cementitious material. Measurements of chloride diffusion in mortar samples (440 kg...

  16. 75 FR 19657 - Barium Chloride From China

    Science.gov (United States)

    2010-04-15

    ... Commission found that the domestic interested party group response to its notice of institution (74 FR 31757... COMMISSION Barium Chloride From China AGENCY: United States International Trade Commission. ACTION: Notice of Commission determination to conduct a full five-year review concerning the antidumping duty order on...

  17. 75 FR 20625 - Barium Chloride From China

    Science.gov (United States)

    2010-04-20

    ... established a schedule for the conduct of this review (74 FR 62587, November 30, 2010). Subsequently, counsel... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Barium Chloride From China AGENCY: United States International Trade Commission. ACTION:...

  18. Chloride concentration affects soil microbial community

    Czech Academy of Sciences Publication Activity Database

    Gryndler, Milan; Rohlenová, Jana; Kopecký, Jan; Matucha, Miroslav

    2008-01-01

    Roč. 71, č. 7 (2008), s. 1401-1408. ISSN 0045-6535 R&D Projects: GA ČR GA526/05/0636 Institutional research plan: CEZ:AV0Z50200510; CEZ:AV0Z50380511 Keywords : soil chloride * terminal restriction fragments * soil microorganisms Subject RIV: EE - Microbiology, Virology Impact factor: 3.054, year: 2008

  19. Determination of chloride in uranium solutions

    Energy Technology Data Exchange (ETDEWEB)

    Danse, A.; Stoch, H.; Steele, T.W.

    1967-05-15

    Thiocyanate is first removed by precipitation with a small excess of a copper solution, and the cations are removed by passing the filtrate through a cation-exchange resin. The chloride is determined in the eluate by a potentiometric titration in which silver nitrate solution is used.

  20. Amperometric Sensor for Detection of Chloride Ions

    Directory of Open Access Journals (Sweden)

    Rene Kizek

    2008-09-01

    Full Text Available Chloride ion sensing is important in many fields such as clinical diagnosis, environmental monitoring and industrial applications. We have measured chloride ions at a carbon paste electrode (CPE and at a CPE modified with solid AgNO3, a solution of AgNO3 and/or solid silver particles. Detection limits (3 S/N for chloride ions were 100 μM, 100 μM and 10 μM for solid AgNO3, solution of AgNO3 and/or solid silver particles, respectively. The CPE modified with silver particles is the most sensitive to the presence chloride ions. After that we approached to the miniaturization of the whole electrochemical instrument. Measurements were carried out on miniaturized instrument consisting of a potentiostat with dimensions 35 × 166 × 125 mm, screen printed electrodes, a peristaltic pump and a PC with control software. Under the most suitable experimental conditions (Britton-Robinson buffer, pH 1.8 and working electrode potential 550 mV we estimated the limit of detection (3 S/N as 500 nM.

  1. Polyvinyl chloride filled with bismuth oxychloride powder

    Czech Academy of Sciences Publication Activity Database

    Polášková, M.; Sedláček, T.; Kharlamov, Alexander; Pivokonský, Radek; Saha, P.

    Larnaca : Polymer Processing Society, 2009, s. 242. [Polymer Processing Society Europe/Africa Regional Meeting. Larnaca (GR), 18.10.2009-21.10.2009] Institutional research plan: CEZ:AV0Z20600510 Keywords : olyvinyl chloride * bismuth oxychloride * radiopaque agents Subject RIV: BK - Fluid Dynamics

  2. Regulated trafficking of the CFTR chloride channel

    NARCIS (Netherlands)

    Braakman, L.J.; Kleizen, B.; Jonge, H.R. de

    2000-01-01

    The cystic fibrosis transmembrane conductance regulator (CFTR), the ABC transporter encoded by the cystic fibrosis gene, is localized in the apical membrane of epithelial cells where it functions as a cyclic AMP-regulated chloride channel and as a regulator of other ion channels and transporters. Wh

  3. Binary nucleation of water and sodium chloride

    Czech Academy of Sciences Publication Activity Database

    Němec, Tomáš; Maršík, František; Palmer, A.

    2006-01-01

    Roč. 124, č. 4 (2006), 0445091-0445096. ISSN 0021-9606 R&D Projects: GA ČR(CZ) GA101/05/2536 Institutional research plan: CEZ:AV0Z20760514 Keywords : binary nucleation * sodium chloride * water Subject RIV: BJ - Thermodynamics Impact factor: 3.166, year: 2006

  4. 21 CFR 184.1446 - Manganese chloride.

    Science.gov (United States)

    2010-04-01

    ..., and crystallized. (b) The ingredient meets the specifications of the Food Chemicals Codex, 3d Ed... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Manganese chloride. 184.1446 Section 184.1446 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD...

  5. Hydrolysis of ferric chloride in solution

    Energy Technology Data Exchange (ETDEWEB)

    Lussiez, G.; Beckstead, L.

    1996-11-01

    The Detox{trademark} process uses concentrated ferric chloride and small amounts of catalysts to oxidize organic compounds. It is under consideration for oxidizing transuranic organic wastes. Although the solution is reused extensively, at some point it will reach the acceptable limit of radioactivity or maximum solubility of the radioisotopes. This solution could be cemented, but the volume would be increased substantially because of the poor compatibility of chlorides and cement. A process has been developed that recovers the chloride ions as HCl and either minimizes the volume of radioactive waste or permits recycling of the radioactive chlorides. The process involves a two-step hydrolysis at atmospheric pressure, or preferably under a slight vacuum, and relatively low temperature, about 200{degrees}C. During the first step of the process, hydrolysis occurs according to the reaction below: FeCl{sub 3 liquid} + H{sub 2}O {r_arrow} FeOCl{sub solid} + 2 HCl{sub gas} During the second step, the hot, solid, iron oxychloride is sprayed with water or placed in contact with steam, and hydrolysis proceeds to the iron oxide according to the following reaction: 2 FeOCl{sub solid} + H{sub 2}O {r_arrow} Fe{sub 2}O{sub 3 solid} + 2 HCl{sub gas}. The iron oxide, which contains radioisotopes, can then be disposed of by cementation or encapsulation. Alternately, these chlorides can be washed off of the solids and can then either be recycled or disposed of in some other way.

  6. Viscosity and density tables of sodium chloride solutions

    Energy Technology Data Exchange (ETDEWEB)

    Fair, J.A.; Ozbek, H. (comps.)

    1977-04-01

    A file is presented containing tabulated data extracted from the scientific literature on the density and viscosity of aqueous sodium chloride solutions. Also included is a bibliography of the properties of aqueous sodium chloride solutions. (MHR)

  7. Relación del efecto analgésico de fentanilo agudo con la regulación a la alta de los receptores 5-HT1A cerebrales en la rata Relationship between the analgesic effect of acute fentanyl and upregulation of brain 5-HT1A receptors in the rat

    Directory of Open Access Journals (Sweden)

    I. Bellido

    2004-07-01

    Full Text Available Los agonistas 5-HT1A presentan efecto analgésico. El efecto analgésico de los agonistas µ puede ser bloqueado por antagonistas selectivos 5-HT1A. Para determinar el mecanismo de producción del sinergismo observado entre los receptores µ y serotoninérgico 5-HT1A en relación con su efecto antinociceptivo, determinamos el efecto analgésico de fentanilo tras estímulo nociceptivo de tipo térmico y mecánico en la rata relacionándolo con la afinidad y la densidad máxima de los receptores 5-HT1A de trece áreas cerebrales mediante técnicas de autorradiografía. Fentanilo presentó un efecto analgésico dosis y tiempo dependiente ante los dos estímulos nociceptivos. Paralelamente a la aparición del efecto analgésico, fentanilo originó una regulación a la alta de los receptores 5-HT1A al incrementar de forma dosis-dependiente su densidad sin modificar su afinidad. La dosis mayor de fentanilo (12,8 µg.kg-1 originó un incremento de la densidad de los receptores 5-HT1A estadísticamente significativo y que se correlacionó de forma positiva con su efecto analgésico en las áreas terminales corticales fronto-parietal externa (+64%, interna (+69% y piriforme (+113%, las regiones del hipocampo CA1 (+111% y DGm (+60%, los núcleos amigdalinos PMCo (+101% y AHiAL (+91% y el hipotálamo (+127%. El efecto analgésico de fentanilo en tratamiento agudo se explicaría, al menos, por dos mecanismos. Su capacidad de estimular la neurotransmisión opiácea actuando directamente sobre los receptores opiáceos µ. Y porque, al incrementar los niveles de 5-HT a nivel central y al regular a la alta los receptores 5-HT1A de zonas cerebrales terminales, se facilitaría la estimulación de estos receptores. Dado que los receptores 5-HT1A postsinápticos actúan como heteroreceptores de efecto inhibidor sobre neuronas no serotoninérgicas originando una hiperpolarización neuronal, fentanilo, al facilitar el estímulo de estos receptores originaría una

  8. Removal of iron contaminant from zirconium chloride solution

    International Nuclear Information System (INIS)

    This patent describes a process for eliminating iron contaminant from an aqueous zirconium chloride solution that has been contaminated with FeCl3 in a plant in which zirconium and hafnium chloride solutions are separated by a main MINK solvent extraction system and the FeCl3 is normally removed from the zirconium chloride solution by a secondary MINK solvent extraction system

  9. Kinetics of Vinyl Chloride Polymerization with Mixture of Initiators

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Kinetic models for the rate constants of vinyl chloride polymerization in the presence of initiator mixtures were proposed. They may be used to design the initiator recipes for the vinyl chloride polymerization with uniform rate at different temperatures at which various grades of poly(vinyl chloride) will be prepared.

  10. Efecto de la quercetina sobre la nefrotoxicidad producida por cadmio

    OpenAIRE

    A. I. Morales Martín; Vicente Sánchez; C. Santiago Sandoval; J Mª Fernández Tagarro; J.M. López Novoa; F. Pérez Barriocanal

    2004-01-01

    El incremento en la producción anual de cadmio ha favorecido que la incidencia de la intoxicación crónica por este elemento haya aumentado en los últimos años. El estrés oxidativo es uno de los mecanismos implicados en la generación del efecto tóxico, manifestándose, entre otras patologías, por una disfunción y lesión renal. La quercetina, un flavonoide muy abundante en la dieta mediterránea, es un potente antioxidante y un buen quelante de metales. Nuestro objetivo fue estudia...

  11. Efectos beneficiosos del chocolate en la salud cardiovascular

    OpenAIRE

    Gómez Juaristi, Miren; L. González-Torres; Bravo, Laura; Bastida, Sara; F. J. Sánchez-Muniz

    2011-01-01

    Desde la antigüedad se ha atribuido al chocolate propiedades saludables que lo han aproximado más hacia un uso terapéutico que alimentario. El presente trabajo revisa algunos estudios relevantes de los efectos del chocolate (y sus componentes activos) sobre diferentes factores de riesgo cardiovascular y señala la necesidad de futuros estudios. El consumo de cacao/chocolate (i) incrementa la actividad antioxidante, (ii) modula la función plaquetaria e inflamación y (iii...

  12. Efecto protector de oleuropeina en inflamación intestinal

    OpenAIRE

    Giner Ventura, Elisa

    2015-01-01

    La colitis ulcerosa (CU) es un desorden inflamatorio intestinal crónico que se caracteriza por la inflamación recurrente del colon. Debido a su desconocida etiología, la búsqueda de nuevos tratamientos farmacológicos está enfocada a mejorar la calidad de vida de los pacientes y reducir la inflamación. Sin embargo, aún con un amplio espectro de medicamentos, un cierto porcentaje de pacientes son resistentes a estas terapias, y además, los efectos secundarios asociados son elevados y, algunos d...

  13. El efecto spillover de la M-30 de Madrid

    OpenAIRE

    López García de Leániz, Cristina; Pérez Prada, Fiamma

    2014-01-01

    Este artículo propone una metodología para medir el efecto desbordamiento o spillover que produce una infraestructura de transporte, en este caso viaria de carácter urbano (M-30), sobre los municipios limítrofes, y su impacto en la movilidad urbana y metropolitana de Madrid. Se utiliza un modelo de demanda de vehículo privado de la región de Madrid para cuantificar el número de viajes de la M-30 con origen o destino en estos municipios.

  14. Los efectos contraproducentes de los Planes de Mano Dura

    OpenAIRE

    Aguilar Villamariona, Jeannette

    2006-01-01

    El presente artículo se ocupa de analizar y mostrar a la luz de las propias estadísticas oficiales el fracaso de las políticas de Mano Dura y Super Mano Dura implementadas en El Salvador en los últimos tres años, en su tarea de combatir la criminalidad y controlar el fenómeno de las pandillas. A su vez, se centra en analizar dos de los principales efectos adversos que la implementación de políticas represivas ha tenido en la inseguridad y en la violencia experimentada en ...

  15. Efectos del entrenamiento en memoria en personas mayores

    OpenAIRE

    Sánchez Caro, Yolanda

    2014-01-01

    El proceso de envejecimiento lleva consigo diferentes cambios a nivel físico y cognitivo. Durante este proceso tienen lugar ciertos déficits de memoria asociados a la edad, pudiéndose mejorar el rendimiento en tareas de memoria, así como la autopercepción de la misma gracias a entrenamientos centrados en este proceso cognitivo. El objetivo de este trabajo es estudiar el efecto de un entrenamiento en memoria sobre el rendimiento objetivo de la misma y quejas subjetivas de los participantes;...

  16. MEMORIA EMOCIONAL: EFECTOS DE LA CORTICOSTERONA SOBRE LOS RECUERDOS

    OpenAIRE

    ELIANA RUETTI; ALBA MUSTACA; MARIANA BENTOSELA

    2008-01-01

    Las hormonas adrenales, administradas inmediatamente antes o después de una tarea de aprendizaje, modulan la memoria. Este efecto varía de acuerdo al tiempo y a la intensidad con que se incrementan las hormonas. La liberación o administración de glucocorticoides inmediatamente antes o después de una tarea, facilitan la memoria. Por el contrario, la elevación o administración de glucocorticoides antes de una prueba de aprendizaje, deteriora la evocación de la información previamente adquirida....

  17. LOS EFECTOS QUE PRODUCE LA CREATINA EN LA PERFORMANCE DEPORTIVA

    OpenAIRE

    Paula Carrillo; María Victoria Gilli

    2011-01-01

    Se ha propuesto realizar una investigación sobre los efectos de la suplementación con creatina como ayuda ergogénica para mejorar la performance deportiva. La investigación consistió en una evaluación del consumo de creatina, en una muestra representativa de deportistas recreacionales y amateurs que concurren a gimnasios habilitados de la ciudad de Pergamino, provincia de Buenos Aires. Las investigaciones disponibles indican que la creatina puede incrementar el contenido muscular de fosfocrea...

  18. Revised Model of Chloride Diffusion in Concrete Bridge by Considering Complex Action of Load and Chloride Binding Capacity

    OpenAIRE

    Xiang, Yiqiang; Guo, DongMei

    2014-01-01

    Coastal concrete bridges will suffer from deterioration of RC structural performance and resistance attenuation because of the chloride penetration and other environment factors. This article discusses current different chloride diffusion models and puts forward the revised model of chloride diffusion in concrete bridge by considering the complex action of load influence and chloride-binding capacity. Comparison of numerical predicted values and relative experimental tests show the presented ...

  19. STABILISATION OF SILTY CLAY SOIL USING CHLORIDE

    Directory of Open Access Journals (Sweden)

    TAMADHER T. ABOOD

    2007-04-01

    Full Text Available The object of this paper is to investigate the effect of adding different chloride compounds including (NaCl, MgCl2, CaCl2 on the engineering properties of silty clay soil. Various amounts of salts (2%, 4%, and 8% were added to the soil to study the effect of salts on the compaction characteristics, consistency limits and compressive strength. The main findings of this study were that the increase in the percentage of each of the chloride compounds increased the maximum dry density and decrease the optimum moisture content. The liquid limit, plastic limit and plasticity index decreased with the increase in salt content. The unconfinedcompressive strength increased as the salt content increased.

  20. BARRIER PROPERTIES OF VINYLIDENE CHLORIDE COPOLYMERS

    Institute of Scientific and Technical Information of China (English)

    LI Yuesheng; WENG Zhixue; HUANG Zhiming; PAN Zuren

    1996-01-01

    The permeability coefficients of a series of copolymers of vinylidene chloride (VDC)with methyl acrylate (MA), butyl acrylate (BA) or vinyl chloride (VC) (as comonomer)to oxygen and carbon dioxide have been measured at 1.0 MPa and 30℃, while those to water vapor have been measured at 30℃ and 100% relative humidity. All the copolymers are semicrystalline. VDC/MA copolymers have lower melting temperature compared with VDC/BA copolymers, while that melting temperature of VDC/VC copolymer is higher than that of VDC/acrylate copolymers with the same VDC content. The barrier property of the copolymers is predominantly controlled by crystallite, free volume fraction, and cohesive energy. The permeability coefficients of VDC/MA copolymers to oxygen, carbon dioxide, and water vapor were successfully correlated with the ratio of free volume to cohesive energy.

  1. Chloride migration in concrete with superabsorbent polymers

    DEFF Research Database (Denmark)

    Hasholt, Marianne Tange; Jensen, Ole Mejlhede

    2015-01-01

    Superabsorbent polymers (SAP) can be used as a means for internal curing of concrete. In the present study, the development of transport properties of concrete with SAP is investigated. The chloride migration coefficient according to NT BUILD 492 is used as a measure of this. Twenty concrete...... mixtures are tested 7, 14, and 28 days after casting. The development of degree of hydration is followed for 20 corresponding paste mixtures. Both when SAP is added with extra water to compensate the SAP water absorption in fresh concrete and without extra water, the internal curing water held by SAP may...... contribute to increase the degree of hydration. No matter if SAP is added with or without extra water, it appears that the so-called gel space ratio can be used as a key parameter to link age and mixture proportions (water-to-cement ratio and SAP dosage) to the resulting chloride migration coefficient; the...

  2. Influence of chloride admixtures on cement matrix durability

    International Nuclear Information System (INIS)

    The influence of various inorganic salts, as chloride admixtures to Portland cement, on the mechanical properties and the durability of the matrix has been studied. The salts used in this study are chromium, nickel and cadmium chlorides. Improved compressive strength values are obtained which have been correlated to the stable metal hydroxide formation in high pH environment. Under static water conditions at 500C, hydrolyzed chloride ions exhibit adverse effects on the matrix durability through rapid release of calcium as calcium chloride in the initial period of leaching. On the contrary, enhanced matrix durability is obtained on long term leaching in the case of cement containing chromium chloride

  3. Acylation of Toluene with Isobutyryl Chloride

    Czech Academy of Sciences Publication Activity Database

    Čejka, Jiří; Klisáková, Jana; Žilková, Naděžda; Červený, L.

    Cape Town, 2004 - ( Steen van, E.), s. 2717-2723 ISBN 0-958-46636-X. [International Zeolite Conference /14./. Cape Town (ZA), 25.04.2004-30.04.2004] R&D Projects: GA ČR GA203/03/0804 Institutional research plan: CEZ:AV0Z4040901 Keywords : acylation of toluene * isobutyryl chloride * zeolites Subject RIV: CF - Physical ; Theoretical Chemistry

  4. Chloride migration in concrete with superabsorbent polymers

    OpenAIRE

    Hasholt, Marianne Tange; Jensen, Ole Mejlhede

    2015-01-01

    Superabsorbent polymers (SAP) can be used as a means for internal curing of concrete. In the present study, the development of transport properties of concrete with SAP is investigated. The chloride migration coefficient according to NT BUILD 492 is used as a measure of this. Twenty concrete mixtures aretested 7, 14, and 28 days after casting. The development of degree of hydration is followed for 20 corresponding paste mixtures.Both when SAP is added with extra water to compensate the SAP wa...

  5. Gasometric titration for dimethylaluminum chloride analysis.

    Science.gov (United States)

    Wang, Lin; Maligres, Peter; Eckenroad, Kyle; Simmons, Bryon

    2016-06-01

    A gasometric titration method was developed to quantitate active alkylaluminum content in dimethylaluminum chloride solution to perform the stoichiometry calculation for the reaction charge. The procedure was reproducible with good precision, and the results showed good correlation with ICP-MS method. The gasometric titration is a simple, inexpensive alternative to analysis via ICP-MS which provides more selective analysis of methylaluminum species without the need for inertion. PMID:27017569

  6. A Duplex Stainless Steel for Chloride Environments

    Science.gov (United States)

    Sridhar, N.; Kolts, J.; Flasche, L. H.

    1985-03-01

    This paper examines the effects of microstructural changes on the corrosion, stress corrosion cracking and corrosion fatigue resistance of a duplex stainless steel to chloride environments. The microstructural changes can be precipitation of phases such as sigma and carbides, or changes in the distribution of austenite and ferrite. The former can be important in hot forming operations while the latter is important in welding. The methods of minimizing these deleterious effects can sometimes be different from those used for austenitic stainless steel.

  7. Electrodeposition of Zinc from Chloride Solution

    OpenAIRE

    NAIK, Yanjerappa Arthoba; VENKATESHA, Thimmappa Venkatarangaiah

    2002-01-01

    The electroplating of zinc is carried out in the presence of 3,4,5-Trimethoxy benzaldehyde from a chloride bath. The bath constituents are optimized through Hull cell experiments. Operating parameters such as pH, temperature, and current density are also optimized. The current efficiency and throwing power are measured at different current densities. Polarization study is carried out under galvanostatic conditions. Corrosion resistance test indicated good protection of steel by the ...

  8. Electrochemical behaviours of scandium in chloride melts

    International Nuclear Information System (INIS)

    Electrochemical behaviour of scandium(3) ions in an eutectic melt of NaCl-KCl-CsCl at 810-850 K is studied by cyclic voltammetry and chronoamperometry. The process of cathodic reduction of scandium complex ions in chloride melts is found to proceed according to the scheme: Sc(3) → Sc(0) and to be controlled by the rate of ScCl63- complex dissociation

  9. (tert-Butyl(2-hydroxyethylammonium chloride

    Directory of Open Access Journals (Sweden)

    Cintya Valerio-Cárdenas

    2014-07-01

    Full Text Available In the cation of the title molecular salt, C6H16NO+·Cl−, the N—C—C—O torsion angle is 176.5 (2°. In the crystal, the cations and chloride ions are linked by N—H...O and O—H...O hydrogen bonds, generating a two-dimensional network parallel to (100.

  10. Manganese laser using manganese chloride as lasant

    Science.gov (United States)

    Chen, C. J.

    1974-01-01

    A manganese vapor laser utilizing manganese chloride as a lasant has been observed and investigated. Lasing is attained by means of two consecutive electrical discharges. The maximum laser output is obtained at a vapor pressure of about 3 torr, a temperature of 680 C, and a time delay between electrical discharges of 150 microsec. The maximum energy density is 1.3 microjoule per cu cm.

  11. Chloride Channel Myotonia: Study of Five Cases

    Directory of Open Access Journals (Sweden)

    M Ghofrani

    2002-09-01

    Full Text Available Chloride channel Myotonia is a form of channelopathy, and Myotonia is its manifestation. Myotonia may be defined as delayed relaxation of skeletal muscle after its contraction. Decreased chloride conductance across the transverse tubular system, renders the muscle membrane hyper-excitable and leads to repetitive firing, creating Myotonia. Myotonia congenital is another name for chloride channel Myotonia. Myotonia congenital appears in autosomal dominant type called Thomson disease, autosomal recessive type called Becker disease, and a type with sporadic occurrence. Symptoms appear in the first or second decade of life. Repeated muscle contraction, the so called warm up, result in resolution of the Myotonia stiffness. Muscle stiffness and hypertrophy is another finding at physical examination. In this study we report on 5 patients, which had clinical and electrical signs of Myotonia. Muscle hypertrophy and warm up phenomena were present in all cases. CPK measurement of all cases were normal. 2 patients underwent muscle biopsy that showed only atrophy and increased central nuclei. In three cases autosomal recessive inheritance (Becker, in one case autosomal dominant inheritance (Thomsen and in one case sporadic occurrence was suggested. With respect to successful results of carbamazepine therapy in 4 patients, and being excellent in one of them, we suggest carbamazepine for the first choice of Myotonia treatment.

  12. An autopsy case of zinc chloride poisoning.

    Science.gov (United States)

    Kondo, Takeshi; Takahashi, Motonori; Watanabe, Seiya; Ebina, Masatomo; Mizu, Daisuke; Ariyoshi, Koichi; Asano, Migiwa; Nagasaki, Yasushi; Ueno, Yasuhiro

    2016-07-01

    Ingestion of large amounts of zinc chloride causes corrosive gastroenteritis with vomiting, abdominal pain, and diarrhea. Some individuals experience shock after ingesting large amounts of zinc chloride, resulting in fatality. Here, we present the results of an administrative autopsy performed on a 70-year-old man who ingested zinc chloride solution and died. After drinking the solution, he developed vomiting, abdominal pain, and diarrhea, and called for an ambulance. Except for tachycardia, his vital signs were stable at presentation. However, he developed hypotension and severe metabolic acidosis and died. The patient's blood zinc concentration on arrival was high at 3030μg/dL. Liver cirrhosis with cloudy yellow ascites was observed, however, there were no clear findings of gastrointestinal perforation. The gastric mucosa was gray-brown, with sclerosis present in all gastric wall layers. Zinc staining was strongly positive in all layers. There was almost no postmortem degeneration of the gastric mucosal epithelium, and hypercontracture of the smooth muscle layer was observed. Measurement of the zinc concentration in the organs revealed the highest concentration in the gastric mucosa, followed by the pancreas and spleen. Clinically, corrosive gastroenteritis was the cause of death. However, although autopsy revealed solidification in the esophagus and gastric mucosa, there were no findings in the small or large intestine. Therefore, metabolic acidosis resulting from organ damage was the direct cause of death. PMID:27497327

  13. Potassium chloride production by microcline chlorination

    International Nuclear Information System (INIS)

    Highlights: • Use of chlorination for the KCl production. • The reagents used were microcline, hydromagnesite and chlorine. • Isothermal and non-isothermal assays were performed in Cl2–N2 mixture. • The chlorination generated KCl at 700 °C. • The chlorination products promote KCl formation. - Abstract: The potassium chloride is one of the most important fertilizers used in agriculture. The current demand of this salt makes interesting the study of potassium chloride production from unconventional potassium resources. In this work the potassium chloride production by chlorination of microcline was investigated. The starting reagents were microcline, hydromagnesite and chlorine. Non-isothermal and isothermal chlorination assays were carried out in a thermogravimetric device adapted to work in corrosive atmospheres. The temperature effect on potassium extraction and the phase transformations produced during chlorination of microcline were studied. The reagents and reaction products were analyzed by X-ray fluorescence (XRF) and X-ray diffraction (XRD). The experimental results indicated that by chlorination of microcline an important extraction of potassium in the temperature range from 800 to 900 °C was produced. Moreover, at 800 °C the forsterite, enstatite and magnesium aluminate spinel phases were generated

  14. Microwave spectrum and structure of nitrosyl chloride

    International Nuclear Information System (INIS)

    The microwave spectra of 15N isotopic species of nitrosyl chloride, 15NO35Cl and 15NO37Cl, have been assigned between 8 and 26 GHz, and the following rotational constants have been obtained: A = 81600 MHz, B = 5693.80 MHz, and C = 5322.44 MHz for 15NO35Cl, A = 81520 MHz, B = 5556.07 MHz, and C = 5201.56 MHz for 15NO37Cl. The microwave spectra of the normal species of nitrosyl chloride as well as the 37Cl species and the 18O species have already been measured by Millen et al. (1961). An analysis of both the rotational constants obtained in this study and the constants by Millen et al. has given the following bond lengths and angle as the complete r sub(s) structural parameters of nitrosyl chloride. r(N-O) = 1.143 +- 0.006 A, r(N-Cl) = 1.973 +- 0.003 A, and 0 +- 0.50. The nuclear quadrupole coupling constants in the N-Cl bond axis system of 15NO35Cl are X sub(zz) = -57.8 MHz and eta = -0.311. (author)

  15. Boldine action against the stannous chloride effect.

    Science.gov (United States)

    Reiniger, I W; Ribeiro da Silva, C; Felzenszwalb, I; de Mattos, J C; de Oliveira, J F; da Silva Dantas, F J; Bezerra, R J; Caldeira-de-Araújo, A; Bernardo-Filho, M

    1999-12-15

    Peumus boldus extract has been used in popular medicine in the treatment of biliar litiase, hepatic insufficiency and liver congestion. Its effects are associated to the substance boldine that is present in its extract. In the present work, we evaluated the influence of boldine both in: (i) the structural conformation of a plasmid pUC 9.1 through gel electrophoresis analysis; and in (ii) the survival of the strain of Escherichia coli AB1157 submitted to reactive oxygen species (ROS), generated by a Fenton like reaction, induced by stannous chloride. Our results show a reduction of the lethal effect induced by stannous chloride on the survival of the E. coli culture in the presence of boldine. The supercoiled form of the plasmid is not modified by stannous chloride in the presence of boldine. We suggest that the protection induced by boldine could be explained by its anti-oxidant mechanism. In this way, the boldine could be reacting with stannous ions, protecting them against the oxidation and, consequently, avoiding the generation of ROS. PMID:10624900

  16. Potassium chloride production by microcline chlorination

    Energy Technology Data Exchange (ETDEWEB)

    Orosco, Pablo, E-mail: porosco@unsl.edu.ar [Instituto de Investigaciones en Tecnología Química (INTEQUI), Chacabuco y Pedernera, San Luis (Argentina); Facultad de Química, Bioquímica y Farmacia, Universidad Nacional de San Luis, Chacabuco y Pedernera, San Luis (Argentina); Ruiz, María del Carmen [Instituto de Investigaciones en Tecnología Química (INTEQUI), Chacabuco y Pedernera, San Luis (Argentina)

    2015-08-10

    Highlights: • Use of chlorination for the KCl production. • The reagents used were microcline, hydromagnesite and chlorine. • Isothermal and non-isothermal assays were performed in Cl{sub 2}–N{sub 2} mixture. • The chlorination generated KCl at 700 °C. • The chlorination products promote KCl formation. - Abstract: The potassium chloride is one of the most important fertilizers used in agriculture. The current demand of this salt makes interesting the study of potassium chloride production from unconventional potassium resources. In this work the potassium chloride production by chlorination of microcline was investigated. The starting reagents were microcline, hydromagnesite and chlorine. Non-isothermal and isothermal chlorination assays were carried out in a thermogravimetric device adapted to work in corrosive atmospheres. The temperature effect on potassium extraction and the phase transformations produced during chlorination of microcline were studied. The reagents and reaction products were analyzed by X-ray fluorescence (XRF) and X-ray diffraction (XRD). The experimental results indicated that by chlorination of microcline an important extraction of potassium in the temperature range from 800 to 900 °C was produced. Moreover, at 800 °C the forsterite, enstatite and magnesium aluminate spinel phases were generated.

  17. Solubility of sodium chloride in superheated steam

    International Nuclear Information System (INIS)

    The solubility of sodium chloride in superheated steam was investigated in laboratory-scale experiments up to 20 MPa and 475 C. These experiments were carried out using a dynamic method where deionized steam was passed through a packed bed of salt crystals in a 500 mL Hastelloy autoclave. The residence time of the steam in the salt bed was sufficient to saturate the steam with the salt. The steam samples were cooled and analyzed by ion chromatography. Correlations based on temperature and density were selected to describe the solubility of sodium chloride in superheated steam. The density dependence is much stronger than the temperature dependence. By using these correlations, it is possible to estimate the solubility of salt in steam at lower densities than those used in the experiments. Enthalpy-entropy diagrams are given that show the steam expansion line in turbines, including curves for constant concentration of sodium chloride solubility in steam. These can be used to analyze where in the steam cycle this salt may deposit. (orig.)

  18. Efecto de la edad y el entrenamiento sobre la memoria

    Directory of Open Access Journals (Sweden)

    Angel M. Elgier

    2010-10-01

    Full Text Available Numerosos antecedentes muestran que el envejecimiento está asociado con el deterioro de algunas capacidades cognitivas, entre ellas la memoria. Hay evidencias que indican que las deficiencias de memoria asociadas con la edad pueden mejorarse con entrenamiento, tanto en adultos jóvenes como maduros. El objetivo de la investigación fue evaluar el efecto de la edad y el entrenamiento sobre una tarea de recuerdo de palabras, comparando un grupo de adultos jóvenes con un grupo de adultos mayores, que recibían o no entrenamiento. Los adultos jóvenes recordaron más palabras que los maduros. Asimismo, el entrenamiento produjo un incremento en la cantidad de palabras recordadas en ambos grupos etareos. Los grupos Jóvenes sin entrenamiento y Maduros con entrenamiento obtuvieron un rendimiento similar. Se discuten las implicancias clínicas del efecto del entrenamiento en adultos jóvenes y maduros.

  19. The Accelerated Test of Chloride Permeability of Concrete

    Institute of Scientific and Technical Information of China (English)

    TAN Ke-feng; ODD E Gjφrv

    2003-01-01

    The availability of accelerated chloride permeability test and the effect of w/c ratio, incorporation of silica fume, maximum aggregate size and aggregate type on the chloride permeability were studied. The mathematic analysis certifies that there is a linear relationship between accelerated test and natural diffusion. Test results show that the chloride permeability of concrete increases as w/c ratio increases whilst a limited amount of replacement of cement with silica fume, the chloride permeability decreases dramatically. The maximum aggregate size in the range of 8 to 25 mm seems also affect chloride permeability but with a much less significant level. The chloride permeability of silica fume lightweight aggregate concrete is very low, especially the concrete made with dry lightweight concrete. The chloride permeability can be evaluated by this accelerated test method.

  20. GSK-3 como posible diana terapéutica en la Enfermedad de Alzheimer : Un nuevo inhibidor de GSK-3 aumenta la densidad y rescata la pérdida de espinas dendríticas causada por Aβ en neuronas corticales primarias.

    OpenAIRE

    Barroeta Espar, Isabel

    2012-01-01

    Un nou inhibidor del glicogen-sintetasa-cinasa-3 (GSK-3) tipus tiadiazolidona (TDZD) va demostrar recentment incrementar la supervivència neuronal i prevenir el dèficit de memòria en un ratolí doble-transgènic (APP-tau). Aquest benefici podria produirse per la prevenció de pèrdua d'espines dendrítiques associada a l'exposició a formes solubles oligomèrics del péptidoβ amiloide (Aβo). Estudiem l'efecte de Aβo i TDZD-8 en la densitat d'espines dendrítiques en neurones primàries corticals de rat...

  1. Efecto acaricida de una mezcla química

    Directory of Open Access Journals (Sweden)

    E. Egea

    2000-02-01

    Full Text Available

    Introducción: Se investiga el efecto de una nueva mezcla química (ATLASAC para el control de ácaros del polvo doméstico, microorganismos cosmopolitas que conviven con el hombre, reconocidos como importante fuente de alergenos y la principal causa de exacerbación de las enfermedades alérgicas. En el medio ambiente de los hogares colombianos se conoce por reportes científicos la prevalencia de varias especies comunes en otros países: Dermatophagoides pteronyssinus, D. Farinae, Blomia tropicales, etc, asociados con asma y/o rinitis. Por todo ello, en el medio ambiente residencial del paciente es importante establecer medidas locativas tendientes a evitar la exposición y el control químico para reducir o eliminar la fuente de alergenos, en especial, los ácaros. Un recurso fácil de aplicar son los acaricidas, los cuales varían en el grado de efectividad y tiempo de protección. En nuestro medio no se tienen productos aprobados como acaricidas. Por tal motivo, esta investigación pretende llenar un vacío en el medio colombiano con una mezcla química con efecto acaricida, en especial sobre aquellos implicados con las enfermedades alérgicas.

    Metodología: Se seleccionaron 25 pacientes definidos por historia clínica como alérgicos y 50 voluntarios que por pruebas cutáneas se descartó sensibilización a ácaros. Inmediatamente después del ingreso se hicieron muestreos para determinar la presencia de ácaros del polvo doméstico y fundamentalmente para obtener cultivos puros.

    Resultados preliminares: 100 ácaros de

  2. Proton pump inhibitors in gastroesophageal reflux disease: a custom-tailored therapeutic regimen Diseñando un traje a la medida: los inhibidores de la bomba de protones en la enfermedad por reflujo gastroesofágico

    Directory of Open Access Journals (Sweden)

    Sergio Sobrino-Cossío

    2012-07-01

    Full Text Available The Montreal Definition and Classification divides Gastroesophageal Reflux Disease (GERD into esophageal symptomatic syndromes (and with mucosal damage and extraesophageal syndromes (with acid established association and proposed association. In typical GERD symptoms, an 8-week treatment with PPIs is satisfactory in most cases (> 90%. Response rates to PPIs in GERD are highly variable, as they also rely on an appropriate clinical diagnosis of the disease; endoscopy differentiates the macroscopic GERD phenotype. The non-erosive variety (50-70% prevalence has a different symptomatic response rate, as gastric acid is not the sole etiology of symptoms. The possible explanations of treatment failure include treatment adherence, PPI metabolism alterations and characteristics, and inadequate diagnosis. Refractory symptoms are related to gastric content neutralization by the chronic use of PPIs. Extraesophageal manifestations are associated with other pathophysiological mechanisms where an autonomic nervous system disturbance gives rise to symptoms. In these clinical entities, the relationship between symptoms and acid needs to be established in order to determine the use of PPIs, or consider other drugs. In other words, so as to "custom-tailor the best-fitting therapy" we need to answer the questions for whom, for what, how and for how long. Finally, PPI safety and tolerability are factors to be considered in elderly patients requiring chronic PPI use, who usually have chronic concomitant illnesses.La Clasificación de Montreal divide la enfermedad por reflujo gastro-esofágico (ERGE en síndromes esofágicos sintomáticos y con daño a la mucosa y en síndromes extraesofágicos con asociación establecida al ácido y asociación propuesta. En síntomas ERGE típicos el tratamiento con inhibidores de la bomba de protones (IBP es satisfactorio (> 90% a 8 semanas en la mayoría de los casos. Las tasas de respuesta a los IBP en la ERGE son muy variables

  3. Relation between chloride exchange diffusion and a conductive chloride pathway across the isolated skin of the toad (Bufo bufo)

    DEFF Research Database (Denmark)

    Kristensen, P; Larsen, Erik Hviid

    1978-01-01

    Substitution of chloride in the outside bathing medium of the toad skin with bromide, iodide, nitrate and sulphate leads to a reduction in the apparent exchange diffusion of chloride across this tissue, and also to a reduction of the chloride current recorded during hyperpolarization. A series of...... systems could be explained as secondary effects due to a primary interaction with the sodium transport mechanisms. A correlation was found between the clamping current recorded during hyperpolarization and the efflux of chloride under short circuit conditions with chloride Ringer's on both sides. On the...

  4. Estudo histopatológico do efeito do tenoxicam com água bidestilada ou com cloreto de sódio a 0,9% no endotélio venoso de coelhos Estudio histopatológico del efecto del tenoxican con agua bidestilada o con cloreto de sodio a 0,9% en el endotélio venoso de conejos Histopathologic study on the effects of tenoxicam with bidistilled water or with 0.9% sodium chloride in rabbits venous endothelium

    Directory of Open Access Journals (Sweden)

    Taylor Brandão Schnaider

    2002-04-01

    increased procoagulant activity. Thrombosis in rabbit auricular veins has been observed after injection of tenoxicam with its diluent or of the diluent alone ². Human studies evaluating venous endothelium after tenoxican injection were not found in the literature. This study aimed at evaluating whether tenoxicam with 0.9% sodium chloride changes the venous endothelium of rabbits as it is observed when associated to its diluent (bidistilled water. METHODS: The study involved 90 rabbits (2000 and 3500 grams divided in two groups: Control group, which received 0.9% NaCl; Experimental group, which received tenoxicam (20 mg with bidistilled water or with 0.9% NaCl. A constant volume of 2 ml was administered to both groups. Anesthesia was induced with acepromazine maleate, ketamine hydrochloride and xylazine hydrochloride, and the puncture of right and left caudal auricular veins was performed with a 27G butterfly needle. Animals were confined for 6 hrs, 12 hrs, and 24 hrs, when they were once more anesthetized and sacrificed, with extraction of the auriculae at their base, followed by microscopic venous study. RESULTS: Thrombosis was observed in 19.4% of the Experimental Group after the administration of tenoxicam with bidistilled water and in 22.2% after the administration of tenoxicam with 0.9% sodium chloride. In the Control group, which has only received 0.9% sodium chloride, no thrombosis was observed. CONCLUSIONS: It was possible to conclude that tenoxicam, either with bidistilled water or 0.9% sodium chloride, has induced thrombosis in the veins it was injected.

  5. Effects of INH, DNP, 2, 4-D and CMU on the sugar content of the barley and maize leaves; Efecto de cuatro inhibidores metabolicos (INH, DNP, 2, 3-D y CMU) sobre el contenido en azucares de hohas de cebada (Hordeum vulgare L.) y Maiz (Zea mais L.)

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, J.; Sancho, P.

    1979-07-01

    1 ppm of the chemicals in nutritive solution was absorbed by barley and maize roots during 24 and 48 hours in dark or light conditioners in order to determine the best conditions. for the obtention of labelled sugars with high specific activity. Results show that the highest specific activity was obtained In maize plants treated with DNP for 24 hours in dark conditions. (Author) 51 refs.

  6. Effects of INH, DNP, 2,4-D and CMU on the photosynthetic activity of barley and maize plants; Efecto de cuatro inhibidores metabolicos (INH, DNP, 2, 4-D y CMU) sobre la actividad fotosintetica de plantular de cebada (Hordeum vulgare L.) y Maiz (Zea mais L.)

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, J.; Prieto, M. P.

    1979-07-01

    Determinations of the rate of photosynthesis were made in barley and maize leaves treated with INH, DNP, 2,4-D or CMU. 1 ppm of the chemicals in nutritive solutions was absorbed by roots during 24 or 48 hours in both dark and light conditions. After this period, photosynthetic activity, compensation point and 14{sup C}O{sub 2} assimilation were determined. Results show that INH increases the rate of photosynthesis, DNP and 2,4-D do not alter it sensibly and CMU acts as a strong inhibitor of photosynthesis. Some possible applications for ths obtention of labelled compounds by biosynthesis are discussed. (Author) 87 refs.

  7. Efecto in vitro de olomoucina en el ciclo celular de linfocitos humanos

    Directory of Open Access Journals (Sweden)

    Camargo M.

    2001-06-01

    Full Text Available La olomoucina, un derivado de purina relacionado con el ATP, ha sido reportado como uneficiente inhibidor del ciclo celular de células animales y vegetales, debido a su alta especificidadpor las ciclinas dependientes de kinasa (CDK CDK1 y CDK2, su capacidad radica en inhibir elciclo celular en las transiciones G2/M y G1/S respectivamente. Con el objetivo de explorar lapotencial aplicación de la olomoucina en el análisis citogenético de alta resolución y estudiosde proliferación celular en cultivos primarios, linfocitos humanos fueron cultivados en RPMI1640 suplementado con suero bovino fetal al 5%, estimuladas durante 72 horas con PHA yposteriormente tratadas con concentraciones de 50, 100 y 200 mM durante 12 y 24 horas.

  8. El efecto de la estancia postdoctoral en la productividad científica

    OpenAIRE

    García-Romero, Antonio

    2000-01-01

    En este trabajo se estudia el efecto que tiene sobre la productividad científica, la realización de una estancia postdoctoral. En primer lugar, se presenta una revisión de la literatura sobre formación de investigadores. En segundo lugar, se estima un modelo basado en la Teoría de Capital Humano para explicar dicho efecto. Los resultados muestran que la productividad es debida tanto a la habilidad de los doctores como a la estancia realizada, si bien el primer efecto es del orden de siete vec...

  9. Efectos reales de la política fiscal en Colombia: 1990-2007

    Directory of Open Access Journals (Sweden)

    Henry Laverde

    2015-12-01

    Full Text Available La evidencia internacional muestra que la actividad económica se veafectada por los choques de la política fiscal. En este trabajo se caracterizan los efectos dinámicos del gasto y los ingresos del Gobierno nacional colombiano sobre el producto interno bruto (PIB y la demanda agregada para el periodo 1990-2007. Para ello se utiliza un modelo estructural de vectores autorregresivos (SVAR con información trimestral. Los resultados evidencian los efectos keynesianos tanto de la tributación como del gasto gubernamental y de sus componentes (consumo e inversión, aunque sus efectos son de bajapersistencia.

  10. Efecto de los tratamientos antirretrovirales en las manifestaciones orales de los pacientes VIH+ Effects of antiretrovial treatments on oral manifestations in HIV+patients

    Directory of Open Access Journals (Sweden)

    E. Jané-Salas

    2006-12-01

    Full Text Available El presente trabajo es un estudio para valorar el efecto de los tratamientos antirretrovirales en pacientes seropositivos al VIH, visitados en el dispensario de enfermedades infecciosas del Hospital Vall D´Hebron de Barcelona. Se visitaron 90 pacientes, 51 varones (56,7% y 39 mujeres (43,3%, siendo la edad media de los pacientes de 36,2 años con una desviación de ±17,8 años y una moda de 35 años. Las visitas fueron realizadas desde enero a diciembre del año 1999. Estos pacientes recibían tratamiento antirretroviral de uno o más fármacos y algunos de ellos (32,2% estaban sometidos a tratamiento antirretroviral de alta actividad (TAAA. Asimismo, en estos pacientes se valoró el recuento de CD4 y carga viral de forma bimodal, al inicio del proceso y en el momento de la visita. La exploración de la cavidad oral se realizó en este momento, buscando las lesiones asociadas al Sida según la clasificación de Pindborg y cols., de 1989. La patología más prevalente encontrada en este estudio fue la sensación de boca seca o xerostomía en un 47,8%, seguida por orden de frecuencia de policaries (34,4% y candidiasis eritematosa (31,1%. Otras manifestaciones orales son muy poco frecuentes, en comparación con los resultados de otros autores en la etapa previa a la utilización de los inhibidores de la proteasa (IP. Así, por ejemplo, se observó un solo caso de leucoplasia vellosa, tan característica antes del año 1996.We evaluate the effects of antiretroviral treatments in HIV seropositive patients, who were seen in the Clinic for Infectious Diseases in the Vall D´Hebron Hospital, Barcelona. 90 patients were seen, 51 males (56.7% and 39 females (43.3%, the mean age of the patients was 36.2 years with a deviation of ±17.8, and a mode of 35 years. The visits were carried out between January and December 1999. These patients were receiving antiretroviral treatment with one or more drugs and some of them (32.2% were subjected to high activity

  11. Molecular mechanisms of carcinogenesis by vinyl chloride.

    Science.gov (United States)

    Dogliotti, Eugenia

    2006-01-01

    In 1974 vinyl chloride (VC), a gas used in the plastics industry, was shown to be a human carcinogen, inducing a very rare type of tumor, angiosarcoma of the liver. The same type of tumor was induced in rodents exposed to VC thus providing an excellent model for mechanistic studies. Here, we review the numerous studies on the mechanism of action of VC with particular emphasis on the DNA products induced by this strong alkylating agent. In particular, the genotoxicity, repair mechanisms, in vivo formation and tumor mutation spectra by etheno-adducts will be analysed and possible approaches for future research suggested. PMID:17033136

  12. Solidification of supercooled molten zinc chloride

    Czech Academy of Sciences Publication Activity Database

    Rodová, Miroslava; Cihlář, Antonín; Nitsch, Karel

    Bratislava: x, 2005 - (Koman, M.; Mikloš, D.), s. 5-9 ISBN 80-89088-42-2. [Development of Materials Science in Research and Education - DMS -RE 2005 /15./. Kežmarské Žĺaby (SK), 05.09.2005-09.09.2005] R&D Projects: GA ČR(CZ) GA202/03/0428 Institutional research plan: CEZ:AV0Z10100521 Keywords : molten zinc chloride * thermal analysis * crystallization * glass formation Subject RIV: BM - Solid Matter Physics ; Magnetism

  13. Benzalkonium Chloride Intoxication Mimicking Herpes Zoster Encephalitis

    Directory of Open Access Journals (Sweden)

    Ekrem Güler

    2011-06-01

    Full Text Available Benzalkonium chloride (BAC is a frequently used disinfectant and its most well-known side effect is contact dermatitis. In this report, two children who had vesicular dermatitis, headache, lethargy, fever and encephalopathy mimicking Herpes zoster encephalitis were presented. Their consciousness level improved on the second day. From the medical history it was understood that the mother had applied 20% BAC solution to the scalps of two children. The aim of the presentation of this report is to draw attention to the fact that BAC application to the scalp for treating pediculosis capitis may resemble the herpes encephalitis clinical picture.

  14. Efecto invernadero o el acto de poseer un cuerpo

    Directory of Open Access Journals (Sweden)

    Daniela Renjel Encinas

    2014-11-01

    Full Text Available Este trabajo aborda la construcción discursiva de la enfermedad terminal como antesala de la muerte y momento culminante de creación y belleza siniestra. El mal es el camino hacia la posesión del cuerpo; el deterioro, la vía de conocimiento y revelación que se opone a la nada, la antagonista de la belleza. Con Efecto invernadero, Bellatin abre la posibilidad de concebir la enfermedad como un imperativo de creación de la obra más importante, el momento final de la propia vida, mediante una escritura que se pule con los años, a manera de un juego cuyas reglas incluyen lo intocable de la vida.

  15. Chloride regulates afferent arteriolar contraction in response to depolarization

    DEFF Research Database (Denmark)

    Hansen, P B; Jensen, B L; Skott, O

    1998-01-01

    afferent arterioles. In 70% of vessels examined, K+-induced contraction was abolished by acute substitution of bath chloride. Consecutive addition of Cl- (30, 60, 80, 100, 110, and 117 mmol/L) restored the sensitivity to K+, and half-maximal response was observed at 82 mmol/L chloride. The calcium channel...... results show that K+-induced contraction of smooth muscle cells in the afferent arteriole is highly sensitive to chloride, whereas neurotransmitter release and ensuing contraction is not dependent on chloride. Thus, there are different activation pathways for depolarizing vasoconstrictors and for the......-Renal vascular reactivity is influenced by the level of dietary salt intake. Recent in vitro data suggest that afferent arteriolar contractility is modulated by extracellular chloride. In the present study, we assessed the influence of chloride on K+-induced contraction in isolated perfused rabbit...

  16. Chloride Ingress in Concrete Cracks under Cyclic Loading

    DEFF Research Database (Denmark)

    Küter, André; Geiker, Mette Rica; Olesen, John Forbes;

    2005-01-01

    increasing focus on the need for modeling the ingress of chloride into cracked concrete. Present models quantify chloride ingress in static cracks only, although several structural applications display dynamic loading conditions in an environment containing chlorides, e.g. marine structures and car parks....... Preliminary investigations have been undertaken to quantify the effect of dynamic load application on the chloride ingress into concrete cracks. Specimens were designed allowing ingress of a chloride solution into a single crack of a saturated unreinforced mortar beam. One set of specimens was subjected to a...... load frequency of ten applications per minute and a second set to one application per hour simulating static cracks, however limiting the ingress hampering effects of autogenous healing and a possible dense precipitation on the crack faces. The averaged chloride exposure interval of the crack faces was...

  17. Anodic Behavior of Alloy 22 in Calcium Chloride and in Calcium Chloride Plus Calcium Nitrate Brines

    Energy Technology Data Exchange (ETDEWEB)

    Evans, K J; Day, S D; Ilevbare, G O; Whalen, M T; King, K J; Hust, G A; Wong, L L; Estill, J C; Rebak, R B

    2003-05-13

    Alloy 22 (UNS N60622) is a nickel-based alloy, which is extensively used in aggressive industrial applications, especially due to its resistance to localized corrosion and stress corrosion cracking in high chloride environments. The purpose of this work was to characterize the anodic behavior of Alloy 22 in concentrated calcium chloride (CaCl{sub 2}) brines and to evaluate the inhibitive effect of nitrate, especially to localized corrosion. Standard electrochemical tests such as polarization resistance and cyclic polarization were used. Results show that the corrosion potential of Alloy 22 was approximately -360 mV in the silver-silver chloride (SSC) scale and independent of the tested temperature. Cyclic polarization tests showed that Alloy 22 was mainly susceptible to localized attack in 5 M CaCl{sub 2} at 75 C and higher temperatures. The addition of nitrate in a molar ratio of chloride to nitrate equal to 10 increased the onset of localized corrosion to approximately 105 C. The addition of nitrate to the solution also decreased the uniform corrosion rate and the passive current of the alloy.

  18. Efectos de los antioxidantes y la fagocitosis bacteriana sobre la apoptosis de los neutrófilos

    OpenAIRE

    Bonilla del Río, Zuriñe

    2013-01-01

    La fagocitosis bacteriana por los neutrófilos retrasa la apoptosis de los mismos cuando la relación bacteria/neutrófilo es baja, y la acelera cuando dicha relación es alta. Las bacterias también inducen en los neutrófilos la producción de sustancias reactivas de oxígeno que incrementarían su apoptosis, y de citoquinas que podrían retrasarla. El antioxidante DPI (difenileniodonio), inhibidor específico de la NADPH oxidasa de los neutrófilos, podría modificar la apoptosis de...

  19. Efecto antiproliferativo y proapoptotico de las estaninas en tumores subcutaneos de A549 implantados en ratones nude

    OpenAIRE

    García de Bravo, Margarita María; Gonzalez, Pedro H.; Salas, Margarita; Galle, Marianela

    2011-01-01

    La familia de las estatinas está constituida por drogas naturales (de origen fúngico), semisintéticas (obtenidas por modificaciones de las anteriores) y sintéticas. Estos compuestos son estructuralmente similares a la mevalonolactona, característica que les posibilita actuar como inhibidores competitivos de la 3-hidroxi-3-metil glutaril CoA reductasa. Esta enzima cataliza la conversión de HMG-CoA en mevalonato y constituye el punto clave en la regulación de la velocidad de la llamada vía del ...

  20. Interactions between chloride ingress and carbonation in cementitious materials

    OpenAIRE

    SAILLIO, Mickael; BARBERON, Fabien; BAROGHEL BOUNY, Véronique; GEGOUT, Philippe; PLATRET, Gérard; D'ESPINOSE DE LA CAILLERIE, JB

    2011-01-01

    Carbonation and chloride attacks are the major causes of reinforced concrete (RC) structure deterioration by initiation of steel rebar corrosion. These attacks are usually studied separately in the literature. Chloride-induced corrosion takes place mainly in marine environment or in the case of contact with deicing salts, while carbonation is systematically present in all RC structures at a variable degree. Since carbonation leads to significant microstructure changes, the effect of chloride ...

  1. Surface Chloride Concentration of Concrete under Shallow Immersion Conditions

    OpenAIRE

    Jun Liu; Kaifeng Tang; Dong Pan; Zongru Lei; Weilun Wang; Feng Xing

    2014-01-01

    Deposition of chloride ions in the surface layer of concrete is investigated in this study. In real concrete structure, chloride ions from the service environment can penetrate into concrete and deposit in the surface layer, to form the boundary condition for further diffusion towards the interior. The deposit amount of chloride ions in the surface layer is normally a function of time, rather than a constant. In the experimental investigation, concrete specimens with different mix proportions...

  2. N,N-Dimethyldehydroabietylammonium chloride ethanol monosolvate

    Directory of Open Access Journals (Sweden)

    Xiu-Zhi Huang

    2013-06-01

    Full Text Available The title compound {systematic name: 1-[(1R,4aS,10aR-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl]-N,N-dimethylmethanaminium chloride ethanol monosolvate}, C22H36N+·Cl−·C2H6O, was synthesized from dehydroabietylamine by N-methylation with formaldehyde/formic acid and transformation into the hydrochloride. The dehydroabietyl moiety exhibits the usual conformation with the two cyclohexane rings in chair and half-chair conformations and a trans-ring junction. The crystal structure is built up from columns of the dehydroabietyl moieties stacked along the a axis. These columns are held together by the chloride ions via N—H...Cl and C—H...Cl interactions, which establish a two-dimensional network parallel to (010. The ethanol solvent molecules are located between the columns and anchored via O—H...Cl hydrogen bonds.

  3. Radiolytic preparation of anhydrous tin (2) chloride

    Science.gov (United States)

    Philipp, W. H.; Marsik, S. J.

    1973-01-01

    Anhydrous tin (2) chloride (SnCl2) is prepared by radiolysis with high energy electrons of a tin (4) chloride (SnCl4) solution in heptane. The SnCl4 is reduced to insoluble SNCl2. The energy yield, G(SnCl2), molecules of SnCl2, produced per 100 eV, increases with SnCl4 concentration from 1.6 at 0.15 M SnCl4 to 3.1 at 3.0 M SnCl4. Other parameters such as temperature total dose and beam current have little influence on G(SnCl2). The method may be used to prepare other metal halides if the higher valence, more covalent metal halide is soluble in aliphatic hydrocarbons and the lower more ionic metal halide is insoluble. The reaction mechanism is discussed; the radiolysis of both heptane and SnCl4 is involved. At high SnCl4 concentration G(SnCl2) appears to be limited by the yield of SnC13 radicals.

  4. Synthesis and structure characterization of diethyldiallylammonium chloride

    Institute of Scientific and Technical Information of China (English)

    刘立华; 龚竹青; 郑雅杰

    2003-01-01

    The unsaturated quaternary ammonium salt diethyldiallylammonium chloride(DEDAAC) was synthesized in a two-step synthetic method. The influences of the adding method of raw materials and temperature on the yields of diethylallylamine (DEAA), and drying and temperature on the synthesis of DEDAAC were investigated. The content of in-process product DEAA was determined by non-aqueous titration. The structure of product DEDAAC was identified with IR, 1 H NMR and elemental analysis. The results show that adding allyl chloride and sodium hydroxide alternately can increase the yield of DEAA and decrease by-products. In further synthesizing of DEDAAC from DEAA, the step of drying DEAA is very necessary. When DEAA is dried by solid sodium hydroxide, good columnar crystals with a high purity(mp 199.5-201.0 ℃) are obtained; when DEAA is undried or the content of water in DEAA is above 20%, only platelets with bad quality are obtained even without crystals. The suitable synthesis conditions for DEAA and DEDAAC are 35 ℃, 6 h and 40 ℃, 36 h, respectively, and their yields are 69.7% and 67.3%, respectively.

  5. Cobalt electrodeposition using urea and choline chloride

    International Nuclear Information System (INIS)

    The electrochemical behavior of Co(II) in urea-choline chloride-CoCl2 melt was investigated by cyclic voltammetry at 373 K. The results show that the reaction of Co(II) to Co is irreversible and it proceeds via a one-step two electrons transfer process. The diffusion coefficient of Co(II) was estimated to be 1.7 × 10−6 cm2 s−1 at 373 K. Electrodeposition of cobalt was studied at different cathodic potentials (-0.80 to -0.95 V) and at different temperatures (353 to 383 K) in eutectic mixture of choline chloride and urea (1:2 molar ratio). The deposits were characterized using scanning electron microscope (SEM), energy-dispersive spectroscopy (EDS), and X-ray diffraction (XRD). SEM images show that uniform, dense, and compact deposits were obtained at -0.80 V within a temperature range of 353 K to 373 K. EDS and XRD analysis confirm that high-purity metallic Co deposits were obtained

  6. The electrodeposition of lead from chloride electrolytes

    Energy Technology Data Exchange (ETDEWEB)

    Wright, A.

    1986-11-28

    At low current densities, lead was deposited onto a lead substrate as a fine powder that did not adhere well to the substrate. At higher current densities dendritic growth occurred. Lead does not adhere to a graphite substrate and, since copper and titanium substrates require higher cell voltages than lead substrates, these three substrates were rejected. The temperature of the electrolyte must be maintained above 69/sup 0/C to avoid the precipitation of lead chloride in the cell. Optimum current efficiencies at the anode and cathode were obtained at 80/sup 0/C, and no improvement in the morphology of the deposit was observed at higher temperatures. A combination of Quebracho extract and cuprous ions achieved the greatest improvement in the morphology of the deposit, while maintaining high current efficiencies at the anode and cathode. However, when the deposition time was increased, dendritic growth was much in evidence. A compact, adherent deposit of lead could not be obtained from chloride electrolytes. 22 refs., 21 figs., 11 tabs.

  7. Open cycle lithium chloride cooling system

    Science.gov (United States)

    Lenz, T. G.; Loef, G. O. G.; Iyer, R.; Wenger, J.

    1983-05-01

    A lithium chloride open cycle absorption chiller has been designed, built and tested. Solution reconcentration takes place in a small counter current packed column supplied with solar heated air. Removal of noncondensable gases that enter the chiller dissolved in the strong solution and the make-up refrigerant streams is accomplished by a liquid-jet ejector and a small vacuum pump. Cooling capacities approaching 1.4 tons and COP levels of 0.58 have been achieved at non-optimum operating conditions. Test results from preliminary system operation suggest that mass transfer processes in both the packed column reconcentrator and the absorber are controlled by concentration gradients in the lithium chloride solution. Liquid phase controlled mass transfer dictates an operating strategy different from the previously assumed gas phase controlled process to obtain maximum rates of evaporation in the packed column. Determination of optimal operating conditions leading to decreased electrical power consumption and improved cooling capacity and coefficient of performance will require further analysis and testing.

  8. Fault locator of an allyl chloride plant

    Directory of Open Access Journals (Sweden)

    Savković-Stevanović Jelenka B.

    2004-01-01

    Full Text Available Process safety analysis, which includes qualitative fault event identification, the relative frequency and event probability functions, as well as consequence analysis, was performed on an allye chloride plant. An event tree for fault diagnosis and cognitive reliability analysis, as well as a troubleshooting system, were developed. Fuzzy inductive reasoning illustrated the advantages compared to crisp inductive reasoning. A qualitative model forecast the future behavior of the system in the case of accident detection and then compared it with the actual measured data. A cognitive model including qualitative and quantitative information by fuzzy logic of the incident scenario was derived as a fault locator for an ally! chloride plant. The obtained results showed the successful application of cognitive dispersion modeling to process safety analysis. A fuzzy inductive reasoner illustrated good performance to discriminate between different types of malfunctions. This fault locator allowed risk analysis and the construction of a fault tolerant system. This study is the first report in the literature showing the cognitive reliability analysis method.

  9. Efectos derrame interestatales y transfronterizos de la red de carreteras: Un estudio para México

    Directory of Open Access Journals (Sweden)

    Inmaculada C. Álvarez Ayuso

    2011-01-01

    Full Text Available El objetivo de esta investigación es identificar la existencia de efectos derrame de la infraestructura carretera nacional y transfronteriza de Estados Unidos sobre la producción en México, a través de la implementación de un modelo de fronteras estocásticas. Para ello, se han elaborado indicadores espaciales que capturan estos efectos y que recogen la influencia de las entidades federativas contiguas a cada una de ellas. Los resultados muestran que tanto las carreteras nacionales como las transfronterizas generan un efecto favorable para la producción, reduciendo la ineficiencia técnica estatal, generando efectos derrame entre las entidades federativas contiguas.

  10. Efectos del entrenamiento de carrera en el rendimiento en ciclismo. Un modelo de entrenamiento del duathlon

    OpenAIRE

    Chavarren Cabrero, Javier

    1996-01-01

    [ES] El duathlon es una disciplina deportiva que combina carrera y ciclismo. Se analiza aquí una de las posibles alternativas de entrenamiento, describiendo sus efectos sobre el rendimiento en competición.

  11. Estimation of trace chloride in nuclear grade sodium

    International Nuclear Information System (INIS)

    The author represents a method to determinate trace levels of chloride in sodium coolant in a fast neutron reactor. Vacuum distillation is used for separating chloride from sodium matrix. After separation, matrix interference from sodium salts is eliminated and a large sample amount can be taken for analysing chloride. In contrast with other similar mercuric thiocyanate colorimetric method in China, this method minimizes a glaring blank of colorimetric solution and determining influence of temperature. Therefore, it increases the precision in analysing chloride. The results of the research demonstrate that when a level of chloride in sodium is less than 1 μg/g, the precision is 37% (n = 10). The recoveries of chloride in high pure sodium demonstrate that when 15-30 μg/g of chloride is added in sodium, the recovery is 97.8%-98.6% and when 4μg/g of chloride is added, then the average recovery is 99.2%. And the relative standard deviation is 16.2% (n =7). It is demonstrated that a monitoring requirement of chloride can be satisfied with this method in coolant of sodium in a fast neutron reactor

  12. Interpretation of postmortem vitreous concentrations of sodium and chloride.

    Science.gov (United States)

    Zilg, B; Alkass, K; Berg, S; Druid, H

    2016-06-01

    Vitreous fluid can be used to analyze sodium and chloride levels in deceased persons, but it remains unclear to what extent such results can be used to diagnose antemortem sodium or chloride imbalances. In this study we present vitreous sodium and chloride levels from more than 3000 cases. We show that vitreous sodium and chloride levels both decrease with approximately 2.2mmol/L per day after death. Since potassium is a well-established marker for postmortem interval (PMI) and easily can be analyzed along with sodium and chloride, we have correlated sodium and chloride levels with the potassium levels and present postmortem reference ranges relative the potassium levels. We found that virtually all cases outside the reference range show signs of antemortem hypo- or hypernatremia. Vitreous sodium or chloride levels can be the only means to diagnose cases of water or salt intoxication, beer potomania or dehydration. We further show that postmortem vitreous sodium and chloride strongly correlate and in practice can be used interchangeably if analysis of one of the ions fails. It has been suggested that vitreous sodium and chloride levels can be used to diagnose drowning or to distinguish saltwater from freshwater drowning. Our results show that in cases of freshwater drowning, vitreous sodium levels are decreased, but that this mainly is an effect of postmortem diffusion between the eye and surrounding water rather than due to the drowning process, since the decrease in sodium levels correlates with immersion time. PMID:27105154

  13. Durability of cracked fibre reinforced concrete structures exposed to chlorides

    DEFF Research Database (Denmark)

    Hansen, Ernst Jan De Place; Ekman, Tom; Hansen, Kurt Kielsgaard

    Durability studies are carried out by subjecting FRC-beams to combined mechanical and environmental load. Mechanical load is obtained by exposing beams to 4-point bending until a predefined crack width is reached, using a newly developed test setup. Exposure to a concentrated chloride solution is...... used as environmental load. The chloride penetration is characterized both qualitatively (UV-test) and quantitatively (chloride profile) and by microscopy. The test programme involves three different concrete qualities. Both steel fibres and polypropylene fibres are used in the concrete beams as well...... as main reinforcement. The effect of the cracks, the fibres and the concrete quality on the chloride penetration is studied....

  14. Catalytic Conversion of Cellulose to Levulinic Acid by Metal Chlorides

    Directory of Open Access Journals (Sweden)

    Beixiao Zhang

    2010-08-01

    Full Text Available The catalytic performance of various metal chlorides in the conversion of cellulose to levulinic acid in liquid water at high temperatures was investigated. The effects of reaction parameters on the yield of levulinic acid were also explored. The results showed that alkali and alkaline earth metal chlorides were not effective in conversion of cellulose, while transition metal chlorides, especially CrCl3, FeCl3 and CuCl2 and a group IIIA metal chloride (AlCl3, exhibited high catalytic activity. The catalytic performance was correlated with the acidity of the reaction system due to the addition of the metal chlorides, but more dependent on the type of metal chloride. Among those metal chlorides, chromium chloride was found to be exceptionally effective for the conversion of cellulose to levulinic acid, affording an optimum yield of 67 mol % after a reaction time of 180 min, at 200 °C, with a catalyst dosage of 0.02 M and substrate concentration of 50 wt %. Chromium metal, most of which was present in its oxide form in the solid sample and only a small part in solution as Cr3+ ion, can be easily separated from the resulting product mixture and recycled. Finally, a plausible reaction scheme for the chromium chloride catalyzed conversion of cellulose in water was proposed.

  15. Efecto de los antipsicóticos sobre la homeostasis intracelular del colesterol

    OpenAIRE

    Canfrán Duque, Alberto

    2013-01-01

    Los antipsicóticos son aminas anfipáticas que se utilizan ampliamente para el tratamiento de ciertos trastornos psiquiátricos por su capacidad de inhibir los receptores D2. Desafortunadamente, algunos de los más utilizados, particularmente los de segunda generación (SGA), producen efectos metabólicos indeseados como ganancia de peso, hipertrigliceridemia e hiperglucemia, con incremento del riesgo cardiovascular. Para explorar los mecanismos potencialmente implicados en estos efectos secundari...

  16. ??Qu?? experimentamos al tomar t??? Estudio cualitativo y efecto farmacol??gico de sus componentes

    OpenAIRE

    Ramos Mart??nez, T.; Campo y Matilla, M.M. del; Slowing Barillas, K.

    2010-01-01

    RESUMEN: Al igual que otras plantas, la Camellia sinensis posee efectos sobre nuestro organismo. La costumbre actual del ???afternoon tea??? en Inglaterra, y el consumo de t?? como bebida placentera (Nestea, Trina t?????) ha hecho que sus efectos farmacol??gicos pasen a un segundo plano sin percatarnos del beneficio que nos aporta. Este estudio pretende mostrar lo que ???desconocemos??? sobre ??l. OBJETIVO: Conocer los principales componentes del t??, su control de calidad y su...

  17. Efectos visuales: desarrollo y evolución a lo largo de la historia del cine

    OpenAIRE

    HERNANDEZ GIRBÉS, GABRIEL

    2015-01-01

    A lo largo de la historia del cine se han utilizado multitud de efectos visuales con el objetivo de asombrar, reducir la peligrosidad o disminuir los costes de representación de algunas escenas. Ante el crecimiento exponencial de los efectos visuales digitales (VFX), este trabajo pretende indagar respecto a las transformaciones tecnológicas que han ido convirtiendo estas formas de trabajo puramente analógicas, al entorno computarizado. De igual forma, comprender la fase prim...

  18. Causas, efectos y políticas para prevenir el efecto rebote de la modernización de regadíos

    OpenAIRE

    Gutiérrez-Martín, Carlos; Berbel, Julio

    2013-01-01

    La existencia de un posible efecto rebote de las medidas de ahorro de agua que lleve a un mayor consumo tiene un cierto carácter novedoso en la política de aguas, y la Unión Europea quiere apostar por la herramienta del precio del agua como solución al posible problema. En nuestra opinión, el conocimiento sobre el efecto rebote no es suficiente en este momento para apostar por un único instrumento hasta que no se conozca con la debida profundidad el fenómeno. Este documento trata de revisar l...

  19. Effect of application of ammonium chloride and calcium chloride on alfalfa cation-anion content and yield.

    Science.gov (United States)

    Goff, J P; Brummer, E C; Henning, S J; Doorenbos, R K; Horst, R L

    2007-11-01

    A major factor predisposing the cow to periparturient hypocalcemia, or milk fever, is being fed a prepartum ration with a high dietary cation-anion difference (DCAD). The DCAD can be favorably altered to prevent milk fever by decreasing K and Na or increasing Cl and S in forages for cows in late gestation. The objective of this study was to test the hypothesis that application of Cl to alfalfa could increase Cl in forage, thereby lowering DCAD. We conducted a field experiment at 2 Iowa locations in which established plots of alfalfa were treated in April 2001 with 0, 56, 112, or 168 kg of Cl/ha using ammonium chloride, calcium chloride, or a mix of the 2 sources with equal amounts of chloride coming from each source. Plots were harvested 4 times in 2001 and once in 2002 and plant tissue analyzed for mineral composition. Applying chloride from either source once in the spring resulted in increased plant chloride content over all 4 cuttings for that year. Averaged across both locations, chloride levels were elevated from 0.52% in control plots to 0.77, 0.87, and 0.89% Cl in plots treated with 56, 112, and 168 kg of Cl/ha, respectively. Chloride application had no effect on plant potassium, sodium, calcium, magnesium, or phosphorus. These results suggest chloride application can elevate chloride content and lower DCAD values of alfalfa, and also maintain crop yield. PMID:17954756

  20. THE COMPATIBILITY OF BLENDS OF POLY(VINYL CHLORIDE) OR CHLORINATED POLY(VINYL CHLORIDE) WITH POLY(METHYL METHACRYLATE)

    Institute of Scientific and Technical Information of China (English)

    WANG Qingguo; CHENG Rongshi

    1988-01-01

    IR spectral shifts of carbonyl vibrational absorption for ethyl acetate, which acts analogically as the structural unit of poly(methyl methacrylate), in cyclohexane, chloroform, chlorinated paraffins, poly(vinyl chloride) and chlorinated poly(vinyl chloride) were measured. The results suggest that there are specific interactions between the carbonyl groups and the chlorinated hydrocarbons which could be responsible for the apparent compatibility of poly(vinyl chloride) -poly(methyl methacrylate) and chlorinated poly(vinyl chloride) -poly(methyl methacrylate) blends. Additionally, the effects of the preparation mode of blend films on phase separation and observed compatibility are discussed.

  1. Aspects of the magnetism of ferrous chloride

    International Nuclear Information System (INIS)

    This work is a critical review of the existing work on ferrous chloride and presents, as well, a number of new experimental results. First, a careful analysis of the level structure of ferrous ions in the crystalline field shows that the crystalline anisotropy is of the same order of magnitude as the exchange interactions, a feature which gives rise to some particular effects, such as an upward curvature of the magnetization curve at 0 K in a perpendicular magnetic field. Further, the very low temperature (T > 0.4 K) thermal variation of both the specific heat and magnetic susceptibility evidences a magnetic component in elementary excitations. This result suggests the presence of a large magneto-elastic coupling. Finally, an experimental study of the H-T phase diagram near TN and of the critical behaviour of the specific heat and parallel susceptibility was performed. (author)

  2. Phosphates behaviours in conversion of FP chlorides

    International Nuclear Information System (INIS)

    The spent electrolyte of the pyroprocessing by metal electrorefining method should be considered for recycling after removal of fission products (FP) such as, alkali metals (AL), alkaline earth metals (ALE), and/or rare earth elements (REE), to reduce the volume of high-level radioactive waste. Among the various methods suggested for this purpose is precipitation by converting FP from chlorides to phosphates. Authors have been carrying out the theoretical analysis and experiment showing the behaviours of phosphate precipitates so as to estimate the feasibility of this method. From acquired results, it was found that AL except lithium and ALE are unlikely to form phosphate precipitates. However their conversion behaviours including REE were compatible with the theoretical analysis; in the case of LaPO4 as one of the REE precipitates, submicron-size particles could be observed while that of Li3PO4 was larger; the precipitates were apt to grow larger at higher temperature; etc.

  3. Estimating the chloride transport in cement paste

    Directory of Open Access Journals (Sweden)

    Princigallo, A.

    2012-06-01

    Full Text Available A method was developed to measure the diffusion coefficient of chloride ions in cement paste based on an analytical solution to Fick’s 2nd law in a cylindrical coordinate system. This natural method yielded diffusivity results within as little as a month. Testing time was reduced by exploiting the three-dimensional inward flux in the specimen. In an attempt to determine the saturation concentration, dense portland cement pastes were exposed to a concentrated chloride solution. The method proved to be useful for exploring cement hydration-induced changes in the diffusion coefficient of cement paste.

    Se ha desarrollado un método para medir el coeficiente de difusión de los iones cloruro en la pasta de cemento, partiendo de una aplicación analítica de la segunda ley de Fick en un sistema de coordinadas cilíndrico. Este método, que es natural, demostró ser capaz de producir resultados de difusividad en tan solo un mes. Se consiguió reducir el tiempo de ensayo mediante el aprovechamiento de la tridimensionalidad del flujo desde el exterior al interior de la probeta. A fin de determinar la concentración de saturación, se sometieron las pastas de cemento Portland a una disolución de cloruros concentrada. Este método resultó ser útil en el estudio de los cambios del coeficiente de difusión de la pasta de cemento provocados por las reacciones de hidratación que tienen lugar en esta.

  4. Coordination compounds of transition metal chlorides with tetrazoles

    International Nuclear Information System (INIS)

    Coordination compounds (CC) of Co(2), Ni(2), Cu(2), Cd(2) chlorides with tetrazole and Ni(2) and Cd(2) chloride CC with tetrazolylhydrazone benzaldehyde are synthesized. The compounds are characterized by electron- and IR-spectroscopy, magnetic measurements (78-300 K), radiography. Conclusions are made on polynuclear structure of coordination compounds and Msup((2)) octahedron coordination

  5. Microwave Mapping Demonstration Using the Thermochromic Cobalt Chloride Equilibrium

    Science.gov (United States)

    Nguyen, Vu D.; Birdwhistell, Kurt R.

    2014-01-01

    An update to the thermochromic cobalt(II) chloride equilibrium demonstration is described. Filter paper that has been saturated with aqueous cobalt(II) chloride is heated for seconds in a microwave oven, producing a color change. The resulting pink and blue map is used to colorfully demonstrate Le Châtelier's principle and to illuminate the…

  6. Probabilistic Models and Computational Methods for Chloride Ingress in Concrete

    DEFF Research Database (Denmark)

    Engelund, S.

    Within the last decades it has been recognized that reinforced concrete structures are subject to a number of destructive mechanisms which might affect the structure in such a way that it is not able to fulfil its purpose efficiently. The present report focuses on chloride ingress and chloride-in...

  7. Prostaglandin synthetase inhibitor in an infant with congenital chloride diarrhoea.

    OpenAIRE

    Minford, A M; Barr, D G

    1980-01-01

    Hyper-reninaemia, hypokaluria, and hypokalaemia in an infant with congenital chloride diarrhoea improved during treatment with a prostaglandin synthetase inhibitor, ketoprofen. There was evidence of increased activity of therenin-aldosterone system when ketoprofen was stopped. It is suggested that prostaglandins may be involved in stimulating the renin-aldosterone system in congenital chloride diarrhoea.

  8. Chlorides behavior in raw fly ash washing experiments

    International Nuclear Information System (INIS)

    Chloride in fly ash from municipal solid waste incinerators (MSWIs) is one of the obstructive substances in recycling fly ash as building materials. As a result, we have to understand the behavior of chlorides in recycling process, such as washing. In this study, we used X-ray absorption near edge structure (XANES) and X-ray diffraction (XRD) to study the chloride behavior in washed residue of raw fly ash (RFA). We found that a combination of XRD and XANES, which is to use XRD to identify the situation of some compounds first and then process XANES data, was an effective way to explain the chlorides behavior in washing process. Approximately 15% of the chlorine in RFA was in the form of NaCl, 10% was in the form of KCl, 51% was CaCl2, and the remainder was in the form of Friedel's salt. In washing experiments not only the mole percentage but also the amount of soluble chlorides including NaCl, KCl and CaCl2 decreases quickly with the increase of liquid to solid (L/S) ratio or washing frequency. However, those of insoluble chlorides decrease slower. Moreover, Friedel's salt and its related compound (11CaO.7Al2O3.CaCl2) were reliable standards for the insoluble chlorides in RFA, which are strongly related to CaCl2. Washing of RFA promoted the release of insoluble chlorides, most of which were in the form of CaCl2.

  9. Stability constants of the Europium complexes with the chloride ions

    International Nuclear Information System (INIS)

    The stability constants of lanthanides complexes with chloride ions which were determined at the same ionic force but in different media, are significantly different. It does not exist a systematic study over these stability constants. The purpose of this work is to determine the stability constants of the europium complexes with chloride ions at 303 K, by the solvents extraction method. (Author)

  10. Monte Carlo calculation of chloride diffusion in concrete

    International Nuclear Information System (INIS)

    Coefficient of chloride diffusion is calculated by applying the Fick's second law of diffusion to a chloride concentration profile. Then from the signal strength for various chlorine gamma-ray energies was then calculated at the detector of the portable D-D neutron generator based PGNAA setup. (author)

  11. Phosphatase inhibitors activate normal and defective CFTR chloride channels.

    OpenAIRE

    Becq, F; Jensen, T J; Chang, X B; Savoia, A.; Rommens, J M; Tsui, L C; Buchwald, M; Riordan, J R; Hanrahan, J W

    1994-01-01

    The cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel is regulated by phosphorylation and dephosphorylation at multiple sites. Although activation by protein kinases has been studied in some detail, the dephosphorylation step has received little attention. This report examines the mechanisms responsible for the dephosphorylation and spontaneous deactivation ("rundown") of CFTR chloride channels excised from transfected Chinese hamster ovary (CHO) and human airway epi...

  12. Contribution on creep polygonization study in crystals. Creep of single crystalline silver chloride and sodium chloride

    International Nuclear Information System (INIS)

    Subgrain formation and their influence on plastic behavior of materials has been studied in the case of single crystals of silver chloride and sodium chloride crept at high temperature (T > 0.5 Tmelting). It is shown that the creep rate ε is a function of the mean subgrain diameter d. For secondary creep ε ∝ dk with k = 2 for NaCl and AgCl. During secondary creep, the substructure changes continuously: sub-boundaries migrate and sub-grains rotate. We find that sub-boundaries migration accounts for 35 pc of the total strain and that subgrain misorientation θ increases linearly with strain ε: θ ∝ 0.14 ε. The stability of permanent creep seems related to the power that the substructure is able to dissipate. The possible subgrain formation mechanisms are examined. It is shown that subgrain formation is closely related to the geometrical conditions of deformation and to the heterogeneities of this later. (author)

  13. EL EFECTO DE LA DESHIDRATACION EN EL RENDIMIENTO ANAEROBICO

    Directory of Open Access Journals (Sweden)

    Fernando Ubiratan Da Silveira

    2006-12-01

    Full Text Available El aumento de la temperatura corporal y la aparición de la sudoración son dos respuestas normales a la actividad física. Sin embargo, la deshidratación y la hipertermia que frecuentemente acompañan el entrenamiento deportivo y a la competición, son las causas más comunes y al mismo tiempo evitables de la fatiga prematura entre los atletas (Murray, 1996. La deshidratación contribuye a la hipertermia reduciendo la capacidad del organismo de perder calor, y aún bajos niveles de deshidratación de tan sólo un 2% del peso corporal perdido, pueden perjudicar el rendimiento físico (Maughan, 2003; Murray, 1996. Los efectos de la deshidratación sobre variables anaeróbicas no son muy claros, debido a los diferentes porcentuales y métodos de deshidratación utilizados en las investigaciones. Por eso, la presente revisión de literatura propone un análisis de los efectos de la deshidratación sobre el rendimiento y metabolismo anaeróbico bajo la organización según tres distintos modelos experimentales: 1. métodos de deshidratación pasiva; 2. métodos de deshidratación activa; 3. método de deshidratación mixto. Así como ocurre en el rendimiento aeróbico, las diferencias en los resultados del rendimiento anaeróbico parecen estar relacionados con algunos factores como: la magnitud de cambio en el peso corporal, el tiempo en que los sujetos estuvieran bajo proceso de deshidratación, las pruebas utilizadas para medir las variables anaeróbicas, los métodos de deshidratación y principalmente si hubo combinación de estos métodos.

  14. EFECTO ABORTIVO DE LOS ANTICONCEPTIVOS HORMONALES: UNA REVISIÓN

    Directory of Open Access Journals (Sweden)

    PAU AGULLES SIMÓ

    2015-01-01

    Full Text Available En gran parte de la comunidad científica, así como del ámbito jurídico, al tratar del embrión no nacido, está vigente el criterio según el cual hay que definir el embarazo como el período que comprende sólo desde la implantación hasta el nacimiento natural. Esto lleva consigo otras novedades; por ejemplo, la redefinición de aborto como la eliminación del embrión sólo en ese período, o la extensión de la anticoncepción a cualquier medio que impida la unión entre los gametos como consecuencia de una relación íntima, o también que elimine el producto de la concepción antes de su implantación. De modo que la industria farmacéutica está lanzando al mercado, bajo el nombre de anticonceptivos, productos que actúan también mediante un mecanismo antiimplantatorio. Este hecho tiene grandes repercusiones éticas con relación al respeto del embrión, que obligan a reflexionar acerca de la valoración moral de la prescripción, dispensación y uso de estos medios. Ahora bien, ¿cuáles de los medios contraceptivos actualmente presentes en el mercado incluyen un efecto antiimplantatorio?, ¿qué mecanismos contribuyen a su acción farmacológica y en qué medida lo hacen? Esto es lo que hemos estudiado en este artículo, basándonos en la bibliografía científica disponible. Aunque no ha sido una tarea sencilla, puesto que los resultados aportados por la literatura varían mucho, se ha tratado de ofrecer una conclusión bastante precisa. Básicamente hemos cumplido un doble objetivo: actualizar y completar los estudios —pocos, parciales o lejanos en el tiempo— que tenían este mismo objeto; y ofrecer una valoración ética respecto al respeto de la vida naciente del uso de los anticonceptivos hormonales que pueden tener efecto antiimplantatorio.

  15. Monoclonal Antibodies to the Apical Chloride Channel in Necturus Gallbladder Inhibit the Chloride Conductance

    Science.gov (United States)

    Finn, Arthur L.; Tsai, Lih-Min; Falk, Ronald J.

    1989-10-01

    Monoclonal antibodies raised by injecting Necturus gallbladder cells into mice were tested for their ability to inhibit the apical chloride conductance induced by elevation of cellular cAMP. Five of these monoclonal antibodies bound to the apical cells, as shown by indirect immunofluorescence microscopy, and inhibited the chloride conductance; one antibody that bound only to subepithelial smooth muscle, by indirect immunofluorescence microscopy, showed no inhibition of chloride transport. The channel or a closely related molecule is present in the membrane whether or not the pathway is open, since, in addition to inhibiting the conductance of the open channel, the antibody also bound to the membrane in the resting state and prevented subsequent opening of the channel. The antibody was shown to recognize, by ELISA, epitopes from the Necturus gallbladder and small intestine. Finally, by Western blot analysis of Necturus gallbladder homogenates, the antibody was shown to recognize two protein bands of Mr 219,000 and Mr 69,000. This antibody should permit isolation and characterization of this important ion channel.

  16. Corrosión electroquímica de medios de molienda y efecto de aniones presentes en aguas industriales

    Directory of Open Access Journals (Sweden)

    Magne, Luis

    2001-02-01

    Full Text Available The steel used in the minerals processing as grinding media (balls or bars, is an important input in terms of cost of the process. Considering the importance of the steel consumption in these processes, this work is guided to evaluate to laboratory scale the effect of the anions present in the industrial waters on the electrochemical corrosion of grinding media. Tests in electrochemical cell, were accomplished measuring potential and corrosion current to four electrodes that were manufactured using sufficiently pure samples of chalcopirite, bornite, enargite and steel ball. The ions used in the tests were chlorides, sulfates, nitrates and carbonates in concentrations from 1 to 180 ppm in individual form or in mixtures, according to the levels measurement of these in industrial waters.

    El acero utilizado como medios de molienda (bolas o barras en el procesamiento de minerales, es una materia prima importante desde el punto de vista de costo del proceso. Considerando la importancia del consumo de acero en estos procesos, este trabajo está orientado a evaluar, a escala de laboratorio, el efecto de los aniones presentes en las aguas industriales sobre la corrosión electroquímica de medios de molienda. Para ello se realizaron ensayos en celda electroquímica, midiendo potenciales y corrientes de corrosión a cuatro electrodos que se fabricaron utilizando muestras suficientemente puras de calcopirita, bornita, enargita y. un trozo de bola de acero. Los iones utilizados en los ensayos fueron cloruros, sulfatos, nitratos y carbonaros en concentraciones desde 1 a 180 ppm, en forma individual o en mezclas de ellos, de acuerdo a la medición de niveles de éstos en aguas industriales de proceso.

  17. Neurociencia y bilingüismo: efecto del primer idioma

    Directory of Open Access Journals (Sweden)

    Germary Díaz-Sánchez

    2013-08-01

    Full Text Available Desde la perspectiva neurobiológica, en este trabajo abordamos los efectos del idioma materno sobre el aprendizaje de una segunda lengua. Aunque existen investigaciones en diferentes países sobre este problema, pocas tratan el enfoque de la neurobiología y, menos aún, cuando se trata del español como idioma materno. Para la investigación se recopiló literatura descriptiva y experimental, con el fin de obtener los datos necesarios para alcanzar los objetivos; se realizó un metaanálisis cualitativo de los datos obtenidos, utilizando tablas de correlación. Los datos reflejaron que la adquisición de un segundo idioma siempre va a estar mediatizada por los esquemas ya establecidos del primer idioma y que existen aspectos neurobiológicos que subyacen a algunos mecanismos de interferencia y a la adquisición de un segundo lenguaje. Además, encontramos que, mientras más similares sean los idiomas, los mecanismos neurales subyacentes facilitan la transferencia del uno al otro.

  18. Efecto del bioestimulante fitomas E en cultivos seleccionados

    Directory of Open Access Journals (Sweden)

    José Villar

    2005-01-01

    Full Text Available FitoMas E es un bioestimulante derivado de la industria azucarera obtenido y desarrollado en el ICIDCA, que ejerce una gran influencia en el desarrollo de las plantas de cultivo. El efecto antiestrés de este producto se manifiesta en una mejora fisiológica global del estado de la planta. En este trabajo se presentan los resultados sobre la floración y el rendimiento en los cultivos de tomate (Licopersicum sculentus variedad Amalia y pepino (Cucumis sativus variedad SS-5 bajo manejo agroecológico. El pepino se plantó en un suelo con indicadores de fertilidad aceptables, pero saturado con valores cercanos a la salinidad. Por su parte, el tomate fue plantado en un suelo con contenido satisfactorio de fósforo y potasio para este cultivo pero bajo en materia orgánica (2.09 %. Se reportan incrementos de 118 % en el número de flores en tomate con 0.7 l/ha de FitoMas E y en el pepino de 147 % y 156 %, respectivamente, para las flores masculinas y femeninas con dosis de 0.2 l/ha del producto. Por otra parte, los incrementos de rendimientos fueron de 333 % en tomate y de 145 % en pepino.

  19. Caesium-137 Chloride Retention following Accidental Ingestion

    International Nuclear Information System (INIS)

    Four men became contaminated with caesium-137 chloride due to leaks in a 100 c source. The source was believed to be completely leak proof, since the caesium chloride was contained in a welded stainless-steel capsule which was covered with an outer steel jacket of standard Oak Ridge design. Most of the contamination occurred while the men were cleaning the components of a pneumatic device used to move the source. The most heavily- contaminated individual placed his mouth over the end of a transport tube and attempted to blow some ''dust'' out of the tube. The other men handled various parts of the transport mechanism and wiped ''dust'' out of holes with their fingers. None of the men washed their hands before eating lunch. When radioactive contamination was discovered on the following day, immediate efforts were made to decontaminate the men. Arrangements for whole-body counts were also made and, on the fifth day following contamination, the men reported to the Radiation Exposure Evaluation laboratory. The body burdens on the fifth day ranged from 35 - 970 nc of caesium-137. During the next five to six days the burdens dropped rapidly and on the eleventh day ranged from 28- 780 nc. After the eleventh day the body burdens of caesium-137 changed much more slowly. Whole-body counts made between the 11th and 160th day yielded biological half-lives of 76, 95 and 126 d for the three most heavily-contaminated individuals. During the period of rapid excretion all urine and faeces were collected and counted. These counts indicated a considerable superficial contamination prior to the eleventh day since only a portion of the removed caesium-137 was found in the urine and stool specimens. The body burdens of the four men are compared with normals of the same size, build, age and diet habits. A short discussion of normal burdens is included. A brief description of the counting system, data handling techniques and calibration procedures is also included. (author)

  20. Study of an aqueous lithium chloride desiccant system Part II: Desiccant regeneration

    Energy Technology Data Exchange (ETDEWEB)

    Fumo, Nelson [Universidad Nacional Experimental del Tachira, San Cristobal (Venezuela); Goswami, Yogi [University of Florida, Gainesville (United States)

    2000-07-01

    Desiccant systems have been proposed as alternative to handle the latent load in vapor compression air conditioning for energy saving. The air dehumidification occurs because of the difference in vapor pressure which let the moisture diffuse from the air to the liquid desiccant. The diffused moisture cause a dilution of the desiccant which must be regenerated to return it to the original conditions. This paper presents the results from a study of the performance of a packed tower regenerator for an aqueous lithium chloride desiccant dehumidification system. The rate of water evaporation, as well as the effectiveness of the regeneration process were assessed under the effects of variables such as air and desiccant flow rates, air temperature and humidity, and desiccant temperature and concentration. A variation of the oeberg and Goswami mathematical model was used to predict the experimental findings given satisfactory results. [Spanish] Se han propuesto sistemas desecantes para hacerse cargo de la carga latente en acondicionamiento de aire por compresion de vapor para el ahorro de energia. La deshumidificacion del aire ocurre en razon de la diferencia de presion de vapor que deja la humedad difusa del aire en el desecante liquido. La humedad difusa del aire origina una dilucion del desecante el cual debe de ser regenerado para regresarlo a sus condiciones originales. Este documento presenta los resultados de un estudio sobre el comportamiento de un regenerador de torre empacada para un sistema de deshumidificacion de solucion desecante de cloruro de litio. El regimen de evaporacion de agua, asi como tambien la efectividad del proceso de regeneracion que se evaluo bajo los efectos de variables tales como los regimenes de flujo de aire y de desecante, temperatura del aire y humedad, y temperatura y concentracion del desecante. Una variacion del modelo matematico de Oberg y Goswami se uso para predecir los resultados experimentales que dieron resultados satisfactorios.

  1. Study of an aqueous lithium chloride desiccant system Part I: Air dehumidification

    Energy Technology Data Exchange (ETDEWEB)

    Fumo, Nelson [Universidad Nacional Experimental del Tachira, San Cristobal (Venezuela); Goswami, Yogi [University of Florida, Gainesville (United States)

    2000-07-01

    Desiccant systems have been proposed as energy saving alternative to vapor compression air conditioning for handling the latent load. Use of liquid desiccants offers several design and performance advantages over solid desiccants, especially when solar energy is used for regeneration. For liquid-gas contact, packed towers with low pressure drop have offered good heat and mass transfer characteristics for compact designs. This paper presents the results from a study of the performance of a packed tower absorber for an aqueous lithium chloride desiccant dehumidification system. The rate of dehumidification, as well as the effectiveness of the dehumidification process were assessed under the effects of variables such as air and desiccant flow rates, air temperature and humidity, and desiccant temperature and concentration. A variation of the oeberg and Goswami mathematical model was used to predict the experimental findings given satisfactory results. [Spanish] Se han propuesto sistemas de desecacion como una alternativa de ahorro de energia para el acondicionamiento de aire mediante la compresion de vapor para manejar la carga latente. El uso de desecantes liquidos ofrece varias ventajas de diseno y de rendimiento sobre los desecantes solidos, especialmente cuando la energia solar se usa para la regeneracion. Para el contacto liquido-gas han dado buenas caracteristicas de transferencia de masa para disenos compactos las torres empacadas con baja caida de presion. Este documento presenta los resultados de un estudio del comportamiento de un absorbedor de torre empacada para una solucion acuosa de desecante de cloruro de litio como sistema de deshumidificacion. El regimen de deshumidificacion asi como tambien la eficiencia del proceso de deshumidificacion se evaluo bajo los efectos de variables tales como regimenes de flujo de aire y de desecante, temperatura del aire y humedad, y concentracion y temperatura del desecante. Se uso una variante de modelo matematico de

  2. NEXAFS and XPS studies of nitrosyl chloride.

    Science.gov (United States)

    Schio, Luca; Li, Cui; Monti, Susanna; Salén, Peter; Yatsyna, Vasyl; Feifel, Raimund; Alagia, Michele; Richter, Robert; Falcinelli, Stefano; Stranges, Stefano; Zhaunerchyk, Vitali; Carravetta, Vincenzo

    2015-04-14

    The electronic structure of nitrosyl chloride (ClNO) has been investigated in the gas phase by X-ray Photoelectron (XPS) and Near Edge X-ray Absorption Fine Structure (NEXAFS) spectroscopy at the Cl 2p, Cl 2s, N 1s and O 1s edges in a combined experimental and theoretical study. The theoretical calculations at different levels of approximation predict ionization potential values in good agreement with the experimental data and allow us to assign the main features of the absorption spectra. An unexpected failure of the density functional model is, however, observed in the calculation of the Cl 2s binding energy, which is related to a large self-interaction error. Largely different photoabsorption cross-section patterns are experimentally observed in core excitations from the investigated quantum shells (n = 1, 2). This finding is confirmed by the oscillator strength distributions calculated at different absorption edges; in the case of the n = 2 shell the bands below the threshold are extremely weak and most of the absorption intensity is due to excitations in the continuum. PMID:25754872

  3. Regulation of neuronal chloride homeostasis by neuromodulators.

    Science.gov (United States)

    Mahadevan, Vivek; Woodin, Melanie A

    2016-05-15

    KCC2 is the central regulator of neuronal Cl(-) homeostasis, and is critical for enabling strong hyperpolarizing synaptic inhibition in the mature brain. KCC2 hypofunction results in decreased inhibition and increased network hyperexcitability that underlies numerous disease states including epilepsy, neuropathic pain and neuropsychiatric disorders. The current holy grail of KCC2 biology is to identify how we can rescue KCC2 hypofunction in order to restore physiological levels of synaptic inhibition and neuronal network activity. It is becoming increasingly clear that diverse cellular signals regulate KCC2 surface expression and function including neurotransmitters and neuromodulators. In the present review we explore the existing evidence that G-protein-coupled receptor (GPCR) signalling can regulate KCC2 activity in numerous regions of the nervous system including the hypothalamus, hippocampus and spinal cord. We present key evidence from the literature suggesting that GPCR signalling is a conserved mechanism for regulating chloride homeostasis. This evidence includes: (1) the activation of group 1 metabotropic glutamate receptors and metabotropic Zn(2+) receptors strengthens GABAergic inhibition in CA3 pyramidal neurons through a regulation of KCC2; (2) activation of the 5-hydroxytryptamine type 2A serotonin receptors upregulates KCC2 cell surface expression and function, restores endogenous inhibition in motoneurons, and reduces spasticity in rats; and (3) activation of A3A-type adenosine receptors rescues KCC2 dysfunction and reverses allodynia in a model of neuropathic pain. We propose that GPCR-signals are novel endogenous Cl(-) extrusion enhancers that may regulate KCC2 function. PMID:26876607

  4. Design of zirconium tetra chloride purification apparatus

    International Nuclear Information System (INIS)

    Design of zirconium tetrachloride purification apparatus was done. The purification was done by sublimation and desublimation of zirconium tetrachloride compound. Zirconium tetrachloride,which was produced by the chlorination processes, was sublimated at 600oC then was desublimated at 331oC. The impurities could be separated. Zirconium tetra chloride was put at the tray in the column heated by the furnace, so that it sublimated. Ferri and Chromi salt was reduced to be ferro and chromo which could not be sublimated. Desublimation, was done in the cooler from pipe which was flowed by water. Cooler mode from 6 pieces of pipe, 1/4 inch in diameter and 30 cm in length. The water flow was 2.8 l/minute. Air was entered in the annulus surrounding the column. From the 80 cm length of the column, 50 cm was used for sublimation, and 30 cm for desublimation. Heat requirement was supplied by a furnace outside of the column. Heat flux could be arranged by the controller. (author)

  5. Redetermination of 1-carboxycyclohexan-1-aminium chloride

    Directory of Open Access Journals (Sweden)

    Teresa González

    2009-02-01

    Full Text Available The crystal structure of the title compound, C7H14NO2+·Cl−, was reported previously [Chacko, Srinivasan & Zand (1975. J. Cryst. Mol. Struct. 5, 353–357] from Weissenberg photographic data with R = 0.113. It has now been redetermined, providing a significant increase in the precision of the derived geometric parameters, viz. mean σ(C—C = 0.003 Å in the present work compared with 0.021 Å for the previous work. The complete cation is generated by crystallographic mirrror symmetry, with three C atoms, two O atoms and the N atom lying on the reflecting plane; the chloride anion also has m site symmetry. The crystal structure is established by a two-dimensional network of O—H...Cl and N—H...Cl hydrogen bonds, generating C12(4 and C12(7 chains, and R24(8 and R24(14 rings.

  6. NQR in tert-butyl chloride

    Science.gov (United States)

    Brunetti, Aldo H.

    2004-03-01

    Tert-butyl chloride has been broadly studied experimentally through various techniques such as X-ray crystallography, DTA, and NMR. It was also studied experimentally through nuclear quadrupole resonance (NQR), but this study was limited and incomplete. In this paper, we present a more detailed study of TBC through the NQR of 35Cl. Our results show that near 120 K, the onset of the CH 3 groups semirotations around symmetry axis C3 takes place with an activation energy U=16.1 kJ mol -1. This intramolecular movement produces a T1 minimum near 148 K and is the dominant mechanism of the nuclear spin-lattice relaxation in phase III of this compound. In phase II of TBC, we show that there are not only methyl groups semirotations, but also semirotations of the whole molecule around a different axis from the symmetry axis C' 3 (C-Cl bond) with an activation energy of E=10.4 kJ mol -1.

  7. Formation of plutonium phosphates in chloride melts

    Energy Technology Data Exchange (ETDEWEB)

    Burnaeva, A.A.; Kryukova, A.I.; Kazanstev, G' N.; Skiba, O.V.; Korshunov, I.A.

    1984-01-01

    Introduction of sodium- and potassium phosphates Na/sub 3/PO/sub 4/ and K/sub 3/PO/sub 4/ in the PuCl/sub 3/-NaCl, PuCl/sub 3/-KCl melts results in reduction of plutonium amount in the liquid phase. Low-soluble plutonium (3) phosphates, of assumed Na/sub 3/Pu/sub 2/ composition (PO/sub 4/)/sub 3/ are transported into the solid phase. Using the methods of radiographical and radiometric analyses the phases of plutonium phosphates separated by precipitation from chloride melt and also prepared from PuO/sub 2/ and NaH/sub 2/PO/sub 4/ at 1200 deg C are investigated. Their solubility in the NaCl-KCl melt and stability to these melts during a long-term contact, and also under the effect of CCl/sub 4/ are evaluated. The data are compared with similar data for thorium-, uranium-, americium-, curium-, zirconium-, rare earth phosphates.

  8. Durability Analysis of Subway Station in Chloride Environment

    Directory of Open Access Journals (Sweden)

    Yang LuFeng

    2013-02-01

    Full Text Available In this study, a finite element model for chloride ions transport in saturated concrete was proposed based on the Fick’s second law of diffusion. The governing partial differential equation was solved numerically in space as a boundary-value problem and in time as an initial-value problem by means of the finite element formulations. The maximum allowable value of chloride diffusion coefficient within different locations of subway station with service life of 100a was achieved and suggestions for durability analysis of subway station in chloride environment were also proposed.

  9. Stochastic Modeling of Reinforced Concrete Structures Exposed to Chloride Attack

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Frier, Christian

    2003-01-01

    For many reinforced concrete structures corrosion of reinforcement is an important problem since it can result in expensive maintenance and repair actions. Further, a significant reduction of the load-bearing capacity can occur. One mode of corrosion initiation is that the chloride content around...... the reinforcement exceeds a critical threshold value. In the present paper a stochastic model is described by which the chloride content in a reinforced concrete structure can be estimated. The chloride ingress is modeled by a 2-dimensional diffusion process and the diffusion coefficient, surface...

  10. Stochastic modeling of reinforced concrete structures exposed to chloride attack

    DEFF Research Database (Denmark)

    Sørensen, John Dalsgaard; Frier, Christian

    2004-01-01

    For many reinforced concrete structures corrosion of reinforcement is an important problem since it can result in expensive maintenance and repair actions. Further, a significant reduction of the load-bearing capacity can occur. One mode of corrosion initiation is that the chloride content around...... the reinforcement exceeds a critical threshold value. In the present paper a stochastic model is described by which the chloride content in a reinforced concrete structure can be estimated. The chloride ingress is modeled by a 2-dimensional diffusion process and the diffusion coefficient, surface...

  11. Molten Triazolium Chloride Systems as New Aluminum Battery Electrolytes

    DEFF Research Database (Denmark)

    Vestergaard, B.; Bjerrum, Niels; Petrushina, Irina;

    1993-01-01

    The possibility of using molten mixtures of 1,4-dimethyl-1,2,4-triazolium chloride (DMTC) and aluminum chloride (AlCl3) as secondary battery electrolytes was studied, in some cases extended by the copresence of sodium chloride. DMTC-AlCl, mixtures demonstrated high specific conductivity in a wide...... of milliamperes per square centimeter) was observed at 0.344 V on the acidic sodium tetrachloroaluminate background, involving a free triazolium radical mechanism. Molten DMTC-AlCl3 electrolytes are acceptable for battery performance and both the aluminum anode and the triazolium electrolyte can be...

  12. Denitrification of fertilizer wastewater at high chloride concentration

    DEFF Research Database (Denmark)

    Ucisik, Ahmed Süheyl; Henze, Mogens

    Wastewater from fertilizer industry is characterized by high contents of chloride concentration, which normally vary between 60 and 76 g/l. Experiments with bilogical denitrification were performed in lab-scale "fill and draw" reactors with synthetic wastewater with chloride concentrations up to 77.......4 g/l. The results of the experiments showed that biological denitrification was feasible at the extreme environmental conditions prevailing in fertilizer wastewater. Stable continuous biological denitrfication of the synthetic high chloride wastewater was performed up to 77.4 g Cl/l at 37 degree C...

  13. Applicability of boron-doped diamond electrode to the degradation of chloride-mediated and chloride-free wastewaters

    International Nuclear Information System (INIS)

    The electrochemical degradation of chloride-mediated and chloride-free dye wastewaters was investigated on a boron-doped diamond (BDD) electrode in comparison with that on a dimensionally stable anode (DSA), and the applicability of BDD electrode to the degradation of these two kinds of wastewaters was explored. In chloride-free wastewater, the electrochemical degradation efficiency of dye on BDD electrode was much higher than that on DSA, with a chemical oxygen demand (COD) removal of 100% and 26% for BDD and DSA, respectively. In chloride-mediated dye wastewater, COD removal was faster than that in chloride-free wastewater on both BDD and DSA electrodes with COD removal efficiencies higher than 95%, whereas the rate of COD removal on DSA was faster than that on BDD electrode. The investigation indicates that DSA is more suitable than BDD electrode in degradation of originally chloride contained dye wastewaters for the sake of energy and time saving. However, for chloride-free dye wastewaters, with the aim of environmental protection, BDD electrode is more appropriate to realize complete mineralization. At the same time, the secondary pollution can be avoided

  14. Efecto de la quercetina sobre la nefrotoxicidad producida por cadmio

    Directory of Open Access Journals (Sweden)

    A. I. Morales Martín

    2004-01-01

    Full Text Available El incremento en la producción anual de cadmio ha favorecido que la incidencia de la intoxicación crónica por este elemento haya aumentado en los últimos años. El estrés oxidativo es uno de los mecanismos implicados en la generación del efecto tóxico, manifestándose, entre otras patologías, por una disfunción y lesión renal. La quercetina, un flavonoide muy abundante en la dieta mediterránea, es un potente antioxidante y un buen quelante de metales. Nuestro objetivo fue estudiar si la administración de quercetina pudiera prevenir la aparición de los procesos nefrotóxicos asociados a la exposición crónica al cadmio. Los experimentos se realizaron con ratas Wistar (200g, incluidas en tres grupos experimentales: 1 ratas a las que se administró cadmio (1,2 mg/kg/día, s.c. cinco veces por semana, durante nueve semanas, 2 ratas a las cuales se les administró quercetina (50 mg/kg/día, i.p. cinco veces por semana, empezando en la cuarta semana y 3 ratas a las que se administró cadmio y quercetina. La lesión renal se evaluó midiendo proteinuria, microalbuminuria y glucosuria, así como la excreción de enzimas urinarias N-acetil-beta-D-glucosaminidasa, fosfatasa alcalina y gamma-glutamil-transpeptidasa. Las muestras de plasma se utilizaron para la determinación de creatinina y nitrógeno ureico plasmático, así como dialdehido malónico, como índice de peroxidación lipídica y antioxidantes totales en plasma. En riñón se midió la actividad enzimática de la superóxido dismutasa y de la glutation reductasa. Nuestros resultados mostraron que la administración de cadmio durante 9 semanas produjo un incremento en los valores de flujo urinario, proteinuria, microalbuminuria y glucosuria. El tratamiento con cadmio incluso incrementó la creatinina sérica y el nitrógeno uréico plasmático y elevó drásticamente la actividad de enzimas urinarias. Finalmente el aclaramiento de creatinina disminuyó como consecuencia de la

  15. Adsorption of Tetradecylpyridinium Chloride on Aqueous Surfaces of Sodium Chloride Solutions

    OpenAIRE

    Fujio, Katsuhiko; Hayashi, Koji; Suzuki, Maki

    2014-01-01

    Surface tension of aqueous NaCl solutions of tetradecylpyridinium chloride (TPC) has been measured by the drop weight method at different NaCl concentrations from 0 to 1.000 mol dm−3 at 25◦C. Surface excess densities of tetradecylpyridinium ion (TP+), Cl− and Na+ have been obtained as functions of TPC concentration at different NaCl concentrations by applying the Gibbs adsorption isotherm to the surface tension data below the critical micelle concentration (CMC) of TPC. Surface excess densiti...

  16. Adsorption of Dodecylpyridinium Chloride on Aqueous Surfaces of Sodium Chloride Solutions

    OpenAIRE

    Fujio, Katsuhiko; TAKEUCHI, Kumiko; Suzuki, Maki

    2012-01-01

    Surface tension of aqueous NaCl solutions of dodecylpyridinium chloride (DPC) has been measured by the drop weight method at different NaCl concentrations from 0 to 1.000 mol dm-3 at 25℃. Applying the Gibbs adsorption isotherm to the surface tension data at DPC concentrations below the critical micelle concentration (CMC), surface excess densities of dodecylpyridinium ion (DP+), Cl- and Na+ have been obtained as functions of DPC concentration at different NaCl concentrations. Surface excess d...

  17. A synthetic chloride channel restores chloride conductance in human cystic fibrosis epithelial cells.

    Directory of Open Access Journals (Sweden)

    Bing Shen

    Full Text Available Mutations in the gene-encoding cystic fibrosis transmembrane conductance regulator (CFTR cause defective transepithelial transport of chloride (Cl(- ions and fluid, thereby becoming responsible for the onset of cystic fibrosis (CF. One strategy to reduce the pathophysiology associated with CF is to increase Cl(- transport through alternative pathways. In this paper, we demonstrate that a small synthetic molecule which forms Cl(- channels to mediate Cl(- transport across lipid bilayer membranes is capable of restoring Cl(- permeability in human CF epithelial cells; as a result, it has the potential to become a lead compound for the treatment of human diseases associated with Cl(- channel dysfunction.

  18. Efecto de los componentes del agua de mar durante el fenómeno de corrosión por picaduras del cobre

    Directory of Open Access Journals (Sweden)

    García, E.

    1995-10-01

    Full Text Available Copper is the main component in Cu-Ni alloys recommended for sea water applications. This work presents the electrochemical behaviour of copper in presence of different sea water components and its influence on the corrosion attack. The combined action of chloride and sulphate ions are the main responsible factor for the localized corrosion attack in the form of pitting. A significant parabolic relation exists between the critical pitting potential (Ep and the weight ratio of chloride to sulphate (Cl-/SO42- ions. Therefore sulphate ions are an important component for pitting corrosion of copper.

    El cobre es el elemento principal de las aleaciones Cu-Ni recomendadas para aplicaciones marinas. En este trabajo se presenta el comportamiento electroquímico del cobre con los diferentes componentes del agua de mar y el efecto de estos sobre la forma de ataque del cobre. Se observó que los iones cloruro, en unión con los iones sulfato, son los principales causantes del fenómeno de corrosión por picaduras, existiendo, además, una relación significativa entre el potencial crítico de picado (Ep y la relación (Cl-/SO42- de tipo parabólico, lo cual pone de manifiesto la importancia del ion sulfato en el fenómeno de corrosión por picaduras como promotor de este tipo de mecanismo.

  19. Insulator contamination effects; Efectos de la contaminacion en aislamientos

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, Lucia [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1986-12-31

    centros de produccion (contaminacion industrial); asimismo, en algunos casos para transportar energia, es necesario atravesar grandes extensiones de territorio en las que no existe vegetacion alguna (contaminacion desertica). Es por ello que el efecto de la contaminacion sobre las instalaciones electricas debe considerarse para lograr un suministro de energia confiable y economico.

  20. EFECTOS PSICOLÓGICOS DE LA LESIÓN DEPORTIVA

    Directory of Open Access Journals (Sweden)

    A. Ramírez

    2010-09-01

    Full Text Available

     

    RESUMEN

    La práctica continuada de la actividad física y deportiva ha sido relacionada con la mejora objetiva del estado de ánimo y el nivel de autoeficacia del deportista. En este estudio, se analizan los efectos que produce la interrupción de la práctica deportiva como consecuencia de la lesión en dichas variables. Los resultados muestran la existencia de diferencias estadísticamente significativas en el estado de ánimo del deportista, pero no en su nivel de habilidad física percibida. Así mismo, se constata una relación positiva entre el nivel de hostilidad y la habilidad física percibida por el sujeto cuando ocurre la lesión.
    PALABRAS CLAVE: Deporte, Lesión, Estado de ánimo, Autoeficacia

    ABSTRACT

    The continued practice of physical activity and sport, has been related with better moods and self-efficiency. This study analyses the consequences on mood disturbance and perception of physical ability that result from an interruption in training as a result of an injury. Significant differences were found in these dependent variables between the injured and non-injured athletes. A significant correlation was also found between self-efficiency and anger at the onset of injury.
    KEY WORDS: Sport, Injury, Self Efficiency, Mood State

  1. Efecto del Cambio de Reglas en Pelota Vasca Escolar

    Directory of Open Access Journals (Sweden)

    Oidui Usabiaga Arruabarrena

    2014-01-01

    Full Text Available El objetivo del presente estudio fue analizar la influencia de las modificaciones de reglas en la acción de juego de los escolares que participaron en un programa de deporte escolar de pelota a mano. La muestra estuvo compuesta por 60 escolares de 8 a 12 años, 35 participaron en seis partidos celebrados durante el curso 2007-08 y los 25 restantes en otros seis enfrentamientos del 2008- 09. El registro se llevó a cabo mediante un instrumento observacional ad hoc y posteriormente se realizó un análisis de las variables: zona y tipo de golpe, ubicación espacial en situación de espera y dirección del saque, resto y juego de intercambio. La comparación (curso 2007-08 y 2008-09 de medias se llevó a cabo mediante el test no paramétrico de U de Mann-Whitney (p < 0,05, con corrección de Bonferroni. Los resultados muestran que, después de modificar las reglas, los jugadores de ambos cursos juegan de forma similar: golpean la pelota con la mano derecha en zonas próximas a la pared frontal e izquierda, se ubican a la derecha del jugador que golpea en los duelos por parejas y a la izquierda en los individuales, dirigen los saques a media distancia, cometen faltas en el resto y juego de intercambio y desarrollan un juego a corta distancia. La única diferencia se encontró en el resto a distancia corta y a la derecha. El análisis de indicadores de juego puede ser de gran ayuda para conocer los efectos de los cambios de reglas en el ámbito formativo.

  2. Efectos de la imagen corporativa en el comportamiento del consumidor. Un estudio aplicado a la banca comercial

    Directory of Open Access Journals (Sweden)

    Rafael Bravo

    2011-06-01

    Full Text Available En este trabajo se analiza el efecto de las dimensiones de imagen corporativa sobre la satisfacción, compromiso y lealtad del cliente hacia su entidad bancaria, así como el efecto moderador de las variables sexo, edad y tipo de entidad en estas relaciones. A través de un estudio empírico se muestra que la dimensión relacionada con el personal es la que tiene un mayor efecto directo sobre la satisfacción y la lealtad. Asimismo, la dimensión de justicia en precios es la que tiene un mayor efecto directo sobre el compromiso. El análisis comparativo por grupos de sexo y edad señala diferencias en los efectos de algunas de las dimensiones de imagen, si bien no se observan diferencias significativas entre los bancos y las cajas de ahorros.

  3. Nickel Chloride Promoted Glaser Coupling Reaction in Hot Water

    Institute of Scientific and Technical Information of China (English)

    Pin Hua LI; Lei WANG; Min WANG; Jin Can YAN

    2004-01-01

    A Glaser coupling reaction of terminal alkynes in the presence of nickel chloride without any organics and bases in hot water has been developed, which produces the corresponding homo-coupling products in good yields.

  4. Chloride supporting electrolytes for all-vanadium redox flow batteries.

    Science.gov (United States)

    Kim, Soowhan; Vijayakumar, M; Wang, Wei; Zhang, Jianlu; Chen, Baowei; Nie, Zimin; Chen, Feng; Hu, Jianzhi; Li, Liyu; Yang, Zhenguo

    2011-10-28

    This paper examines vanadium chloride solutions as electrolytes for an all-vanadium redox flow battery. The chloride solutions were capable of dissolving more than 2.3 M vanadium at varied valence states and remained stable at 0-50 °C. The improved stability appeared due to the formation of a vanadium dinuclear [V(2)O(3)·4H(2)O](4+) or a dinuclear-chloro complex [V(2)O(3)Cl·3H(2)O](3+) in the solutions over a wide temperature range. The all-vanadium redox flow batteries with the chloride electrolytes demonstrated excellent reversibility and fairly high efficiencies. Only negligible, if any, gas evolution was observed. The improved energy capacity and good performance, along with the ease in heat management, would lead to substantial reduction in capital cost and life-cycle cost, making the vanadium chloride redox flow battery a promising candidate for stationary applications. PMID:21922094

  5. Catalytic Decomposition of Methylene Chloride by Sulfated Titania Catalysts

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Catalytic decomposition of methylene chloride in air below 300℃ was studied.Sulfated titania was very effective in converting 959ppm methylene chloride selectively to CO,CO2 and HCl.Complete decomposition of methylene chloride was achieved at low temperature(275℃).It was found that the acidic property of catalyst was a determinant factor for the catalytic activity.The presence of water vapor in the feed stream remarkably reduced the catalytic activity,which could be due to the blockage of acidic sites on the surface of catalyst by water molecules.A bifunctional catalyst comprising copper oxide was developed to improve the selectivity of catalytic oxidation,which indicated that copper oxide can promote the deep oxidation of methylene chloride.The crystal form of TiO2 imposes an important influence upon the catalytic oxidation.

  6. Thermodynamic calculation of self-diffusion in sodium chloride

    Science.gov (United States)

    Zhang, Baohua; Li, Chengbo; Shan, Shuangming

    2016-05-01

    Using the available pressure-volume-temperature equation of state of sodium chloride, we show that the self-diffusion coefficients of sodium and chloride in sodium chloride as a function of temperature and pressure can be successfully reproduced in terms of bulk elastic and expansivity data. We use a thermodynamic model that interconnects point-defect parameters with bulk properties. Our calculated diffusion coefficients and point-defect parameters, including activation enthalpy, activation entropy, and activation volume, well agree with reported experimental results when uncertainties are considered. Furthermore, the ionic conductivity of sodium chloride inferred from our predicted diffusivities of sodium through the Nernst-Einstein equation is compared with previous experimental data.

  7. Laboratory stress corrosion cracking studies with sulfur acids and chlorides

    Energy Technology Data Exchange (ETDEWEB)

    Baylor, V.B.

    1985-10-01

    Stress corrosion cracking (SCC) caused by polythionic acid and/or chlorides has occurred in coal liquefaction pilot plants. This problem is also common in refineries and has been extensively researched. This study examines: (1) the relationship of the ASTM standard ferric sulfate-sulfuric acid test for determining sensitization to resistance to polythionic SCC; (2) the cracking resistance of higher-alloy. Fe-Ni-Cr materials and common austenitic stainless steels (SS); and (3) the effect of chloride concentrations up to 1% in polythionic acid solutions on cracking behavior. The ferric sulfatesulfuric acid test can be used as an acceptance test for materials resistant to polythionic acid SCC. More highly alloyed materials were more resistant to sensitization than most austenitic SS and were virtually unattacked in polythionic acid solutions containing up to 1% chloride. Chloride increased the corrosion rate and caused localized pitting but it did not significantly affect the number of failures or the failure mode.

  8. Use of saturated sodium chloride solution as a tissue fixative

    Directory of Open Access Journals (Sweden)

    A. Al-Saraj

    2010-01-01

    Full Text Available The present study was carried out to examine the capability of saturated sodium chloride solution as a fixative agent instead of formalin which is regarded as a carcinogenic material. For this purpose 3 rabbits were used and their livers, kidneys and spleens were exposed and removed. Neutral buffered formalin solution, saturated sodium chloride solution and distilled water were used as fixatives for specimens obtained from the first, second and third rabbits respectively. Routine histological technique was performed to prepare a stained histological sections for light microscopic examination. The result showed that the tissue sections which were obtained by using sodium chloride have the same histological features and without any artifacts when they compared with the results obtained using formalin fixation method. We conclude that the saturated sodium chloride solution can be used as a fixative agent in some circumstances when no any fixative agent is available.

  9. Solidification of spent TBP solvent with aluminium chloride compounds

    International Nuclear Information System (INIS)

    The new techniques for processing spent TBP was investigated. It was proved that treatment of TBP containing DBP with aluminium chloride resulted in the formation of aluminium phosphate suitable for long term storage and final disposal

  10. Methyltrioctylammonium chloride catalysed sonochemical synthesis of acridine diones

    Indian Academy of Sciences (India)

    Bhupinder Kaur; Harish Kumar

    2013-09-01

    The greener, clean and efficient protocol for the synthesis of acridine diones derivatives has been achieved by reacting aromatic aldehyde, dimedone and amines using methyltrioctylammonium chloride (Aliquate 336) as a catalyst under ultrasonic irradiations.

  11. Mechanisms of chloride decomposition in upgrading oil sands bitumen

    Energy Technology Data Exchange (ETDEWEB)

    Le, T.; Diaz, D.; Gray, M. [Alberta Univ., Edmonton, AB (Canada). Dept. of Chemical and Materials Engineering; Eaton, P. [Champion Technologies, Fresno, TX (United States); Wu, A. [Syncrude Canada Ltd., Edmonton, AB (Canada). Edmonton Research Centre

    2004-07-01

    In addition to clay minerals, bitumens from mining operations contain chloride salts because of the salinity of the extraction process water and the connate water in the ore. These chlorides form corrosive hydrochloric acid. High concentrations of organic acid components known as naphthenic acids are also found in bitumen from Alberta's oil sands. These also cause corrosion. Chloride salts, clays and organic acids may interact in the presence of steam to promote hydrochloric acid formation causing major corrosion problems in downstream facilities. This study examined the behaviour of these components under upgrading conditions. In particular, it examined the rate and the extent of the hydrolysis reactions for salts found in bitumen. Mixtures of bitumen, salts and organic acids were exposed to flowing steam at 100 to 400 degrees C under nitrogen purge. Ion chromatography was used to analyze the condensed vapours for chloride.

  12. Purification and reconstitution of chloride channels from kidney and trachea

    International Nuclear Information System (INIS)

    Chloride channels mediate absorption and secretion of fluid in epithelia, and the regulation of these channels is now known to be defective in cystic fibrosis. Indanyl-oxyacetic acid 94 (IAA-94) is a high-affinity ligand for the chloride channel, and an affinity resin based on that structure was developed. Solubilized proteins from kidney and trachea membranes were applied to the affinity matrix, and four proteins with apparent molecular masses of 97, 64, 40, and 27 kilodaltons were eluted from the column by excess IAA-94. A potential-dependent 36Cl- uptake was observed after reconstituting these proteins into liposomes. Three types of chloride channels with single-channel conductances of 26, 100, and 400 picosiemens were observed after fusion of these liposomes with planar lipid bilayers. Similar types of chloride channels have been observed in epithelia

  13. Reinforcement corrosion in alkaline chloride media with reduced oxygen concentrations

    International Nuclear Information System (INIS)

    It is commonly considered that the corrosion of steel in concrete is controlled by the oxygen content of the pore solution and there are service life models that relate the corrosion rate to the amount of oxygen. It is also commonly believed that in water saturated conditions the oxygen content in the pores is negligible and that underwater there is no risk of depassivation and the corrosion rate is very low. However, the available data on corrosion rates in immersed conditions do not indicate such performance; on the contrary corrosion develops when sufficient chloride reaches the reinforcement. In the present paper, results are presented for tests performed in alkaline chloride solutions that were purged with nitrogen to reduce the oxygen content. The results indicate that at very low oxygen concentrations, corrosion may develop in the presence of chlorides. The presence or absence of corrosion is influenced by the amount of chloride, the corrosion potential and the steel surface condition. (authors)

  14. Micellar solubilization in strongly interacting binary surfactant systems. [Binary surfactant systems of: dodecyltrimethylammonium chloride + sodium dodecyl sulfate; benzyldimethyltetradecylammonium chloride + tetradecyltrimethylammonium chloride

    Energy Technology Data Exchange (ETDEWEB)

    Treiner, C. (Universite Pierre et Marie Curie, Paris (France)); Nortz, M.; Vaution, C. (Faculte de Pharmacie de Paris-sud, Chatenay-Malabry (France))

    1990-07-01

    The apparent partition coefficient P of barbituric acids between micelles and water has been determined in mixed binary surfactant solutions from solubility measurements in the whole micellar composition range. The binary systems chosen ranged from the strongly interacting system dodecyltrimethylammonium chloride + sodium dodecyl sulfate to weakly interacting systems such as benzyldimethyltetradecylammonium chloride + tetradecyltrimethyammonium chloride. In all cases studied, mixed micelle formation is unfavorable to micellar solubilization. A correlation is found between the unlike surfactants interaction energy, as measured by the regular solution parameter {beta} and the solute partition coefficient change upon surfactant mixing. By use of literature data on micellar solubilization in binary surfactant solutions, it is shown that the change of P for solutes which are solubilized by surface adsorption is generally governed by the sign and amplitude of the interaction parameter {beta}.

  15. Electromagnetic-induction logging to monitor changing chloride concentrations

    Science.gov (United States)

    Metzger, Loren F.; Izbicki, John A.

    2013-01-01

    Water from the San Joaquin Delta, having chloride concentrations up to 3590 mg/L, has intruded fresh water aquifers underlying Stockton, California. Changes in chloride concentrations at depth within these aquifers were evaluated using sequential electromagnetic (EM) induction logs collected during 2004 through 2007 at seven multiple-well sites as deep as 268 m. Sequential EM logging is useful for identifying changes in groundwater quality through polyvinyl chloride-cased wells in intervals not screened by wells. These unscreened intervals represent more than 90% of the aquifer at the sites studied. Sequential EM logging suggested degrading groundwater quality in numerous thin intervals, typically between 1 and 7 m in thickness, especially in the northern part of the study area. Some of these intervals were unscreened by wells, and would not have been identified by traditional groundwater sample collection. Sequential logging also identified intervals with improving water quality—possibly due to groundwater management practices that have limited pumping and promoted artificial recharge. EM resistivity was correlated with chloride concentrations in sampled wells and in water from core material. Natural gamma log data were used to account for the effect of aquifer lithology on EM resistivity. Results of this study show that a sequential EM logging is useful for identifying and monitoring the movement of high-chloride water, having lower salinities and chloride concentrations than sea water, in aquifer intervals not screened by wells, and that increases in chloride in water from wells in the area are consistent with high-chloride water originating from the San Joaquin Delta rather than from the underlying saline aquifer.

  16. Local impermeant anions establish the neuronal chloride concentration

    DEFF Research Database (Denmark)

    Glykys, J; Dzhala, V; Egawa, K;

    2014-01-01

    Neuronal intracellular chloride concentration [Cl(-)](i) is an important determinant of γ-aminobutyric acid type A (GABA(A)) receptor (GABA(A)R)-mediated inhibition and cytoplasmic volume regulation. Equilibrative cation-chloride cotransporters (CCCs) move Cl(-) across the membrane, but accumulat...... anions determine the homeostatic set point for [Cl(-)], and hence, neuronal volume and the polarity of local GABA(A)R signaling....

  17. Influence of cracks on chloride penetration and corrosion initiation time

    OpenAIRE

    Audenaert, K.; De Schutter, G.; L. Marsavina

    2009-01-01

    Chloride initiated reinforcement corrosion is the main durability problem for concrete structures in a marine environment. If the chlorides reach the reinforcement steel, it will depassivate and start to corrode in presence of air and water. Since the corrosion products have a larger volume than the intial products, concrete stresses are induced, leading to spalling and degradation of the concrete structures. If cracks, caused by early drying, thermal effects, shrinkage or overstress, are pre...

  18. Optical Studies on Sol-Gel Derived Lead Chloride Crystals

    OpenAIRE

    Rejeena, I; Lillibai, B; Nithyaja, B; Nampoori, P.N V; P. Radhakrishnan

    2013-01-01

    Optical characterization of lead chloride crystals prepared by sol-gel method is reported. The relevant sol-gel technique is used for the preparation of PbCl2 samples with five different types. In this paper, we report the absorption and fluorescence behaviour of pure, UV& IR irradiated and electric & magnetic field applied lead chloride crystal samples in solution phase at two different concentrations. Optical bandgap and emission studies of these crystals are also done.

  19. Recovering germanium from coal ash by chlorination with ammonium chloride

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    A new process of enriching germanium from coal ash was developed. The process involves in mixing the coal ash and ammonium chloride and then roasting the mixture to produce germanium chloride that is then absorbed by dilute hydrochloric acid and hydrolyzed to germanium oxide. The germanium recovery reached to 80.2% at the optimum condition: mass ratio of NH4Cl/coal ash is 0.15, roasting temperature 400℃ and roasting time 90 min.

  20. Polarization and Charge Transfer in the Hydration of Chloride Ions

    OpenAIRE

    Zhao, Zhen; Rogers, David M.; Beck, Thomas L.

    2009-01-01

    A theoretical study of the structural and electronic properties of the chloride ion and water molecules in the first hydration shell is presented. The calculations are performed on an ensemble of configurations obtained from molecular dynamics simulations of a single chloride ion in bulk water. The simulations utilize the polarizable AMOEBA force field for trajectory generation, and MP2-level calculations are performed to examine the electronic structure properties of the ions and surrounding...

  1. Effect of kaolin treatment temperature on mortar chloride permeability

    OpenAIRE

    Puertas, F.; Mejía de Gutiérrez, R.; J. Torres

    2007-01-01

    The present paper discusses the results of chloride resistance tests conducted on ordinary Portland cement (OPC) mortars containing a Colombian kaolin pre-treated at temperatures of from 600 to 800 ºC. The resulting metakaolin (MK) was added to OPC mortar mixes in proportions of 10 and 20% by cement weight. The mortars were compared for physical and chemical properties, including capillary absorption, chloride permeability and pore microstructure as assessed by mercury porosimetry....

  2. Extraction and immobilization of simulated pyrometallurgical chloride waste in Zeolite

    International Nuclear Information System (INIS)

    Zeolites are effective media for the removal and immobilization of fission products waste from pyrometallurgical reprocessing of nuclear fuels. In the present study, equilibration experiments between zeolite 4A and a simulated: pyrometallurgical chloride waste were carried out. Several batches of equilibration were carried out by varying the zeolite to salt (Z/S) ratio. The effects of Z/S on the extraction behaviour of the waste chloride salts were explored. (author)

  3. Intracellular chloride concentration of the mouse vomeronasal neuron

    OpenAIRE

    Kim, Sangseong; Ma, Limei; Unruh, Jay; McKinney, Sean; Yu, C. Ron

    2015-01-01

    Background The vomeronasal organ (VNO) is specialized in detecting pheromone and heterospecific cues in the environment. Recent studies demonstrate the involvement of multiple ion channels in VNO signal transduction, including the calcium-activated chloride channels (CACCs). Opening of CACCs appears to result in activation of VNO neuron through outflow of Cl− ions. However, the intracellular Cl− concentration remains undetermined. Results We used the chloride ion quenching dye, MQAE, to measu...

  4. Computational modelling of chloride ion transport in reinforced concrete

    OpenAIRE

    Meijers, S.J.H.; Bijen, J.M.J.M.; De Borst, R.; Fraaij, A.L.A.

    2001-01-01

    Exposure to a saline environment is a major threat with respect to the durability of reinforced concrete structures. The chloride ions, which are present in seawater and de-icing salts, are able to penetrate the concrete up to the depth of the reinforcement. They can eventually trigger a pitting corrosion process. The assessment of a corrosion-free service life of concrete structures is of paramount economic interest. However, the modelling of the ingress of chloride ions is complicated due t...

  5. Large Scale Synthesis of Carbon Nanofibres on Sodium Chloride Support

    OpenAIRE

    Ravindra Rajarao; Badekai Ramachandra Bhat

    2012-01-01

    Large scale synthesis of carbon nanofibres (CNFs) on a sodium chloride support has been achieved. CNFs have been synthesized using metal oxalate (Ni, Co and Fe) as catalyst precursors at 680 C by chemical vapour deposition method. Upon pyrolysis, this catalyst precursors yield catalyst nanoparticles directly. The sodium chloride was used as a catalyst support, it was chosen because of its non‐toxic and water soluble nature. Problems, such as the detrimental effect of CNFs, the detrimental ef...

  6. Durability Analysis of Subway Station in Chloride Environment

    OpenAIRE

    Yang LuFeng; Yu Bo; Hong Bin

    2013-01-01

    In this study, a finite element model for chloride ions transport in saturated concrete was proposed based on the Fick’s second law of diffusion. The governing partial differential equation was solved numerically in space as a boundary-value problem and in time as an initial-value problem by means of the finite element formulations. The maximum allowable value of chloride diffusion coefficient within different locations of subway station with service life of 100a was achieved and suggestions ...

  7. Influence of cracks on chloride penetration in concrete

    OpenAIRE

    Audenaert, K.; Schutter, G. de; MARSAVINA, L

    2009-01-01

    Chloride initiated reinforcement corrosion is the main durability problem for concrete structures in a marine environment. If the chlorides reach the reinforcement steel, it will depassivate and start to corrode in presence of air and water. Since the corrosion products have a larger volume than the initial products, concrete stresses are induced, leading to spalling and degradation of the concrete structures. If cracks, caused by early drying, thermal effects, shrinkage movements or overstre...

  8. cis-Dichloridobis(1,10-phenanthrolinechromium(III chloride

    Directory of Open Access Journals (Sweden)

    Xiaoli Gao

    2011-02-01

    Full Text Available In the title complex, [CrCl2(C12H8N22]Cl, the CrIII ion is situated on a twofold rotation axis and displays a slightly distorted octahedral CrCl2N4 coordination geometry. The Cr environment is composed of a cis arrangement of two 1,10-phenanthroline and two chloride ligands. The chloride counter-anion exhibits half-occupation and is equally disordered over two positions.

  9. Density Functional Theory Study on Conformers of Benzoylcholine Chloride

    OpenAIRE

    Mustafa Karakaya; Fatih Ucun; Ahmet Tokatlı

    2013-01-01

    The optimized molecular structures and vibrational frequencies and also gauge including atomic orbital (GIAO) 1H and 13C NMR shift values of benzoylcholine chloride [(2-benzoyloxyethyl) trimethyl ammonium chloride] have been calculated using density functional theory (B3LYP) method with 6-31++G(d) basis set. The comparison of the experimental and calculated infrared (IR), Raman, and nuclear magnetic resonance (NMR) spectra has indicated that the experimental spectra are formed from the superp...

  10. Efecto de un extracto de Petiveria Alliacea Lin sobre el crecimiento de Giardia lamblia in vitro

    OpenAIRE

    Aimée Echevarría; Dinorah Torres Idavoy

    2001-01-01

    Se evaluó el efecto de un extracto fluido elaborado con un menstruo de Petiveria alliacea (anamú) sobre el crecimiento in vitro de Giardia lamblia. Para este ensayo se empleó una cepa aislada en el Instituto de Medicina Tropical "Pedro Kourí", procedente de un paciente infestado. Los cultivos fueron incubados a 37 °C durante 48 h y posteriormente ajustada su concentración a 2 ´105 parásitos por 0,5 mL. Los resultados obtenidos muestran un marcado efecto antigiardiásico, por los altos porcenta...

  11. EDITORIAL EFECTOS ADVERSOS DE MEDICAMENTOS: UNA PATOLOGÍA MULTIFORME RESPONSABILIDAD

    OpenAIRE

    Joan-Ramon Laporte

    2009-01-01

    Quizá todavía haya profesionales que, cuando oyen hablar de efectos adversos de medicamentos, piensen en erupciones cutáneas, discrasias hemáticas, shock anafiláctico o incluso malformaciones congénitas. Los citados son efectos adversos reales, pero relativamente raros. Además, son inesperados, no relacionados con la acción farmacológica, imprevisibles e independientes de la dosis. Son como una lotería terapéutica, que dependería de «la suerte».No obstante, cuando se examina la patología farm...

  12. Efecto del clorhidrato de tiaprida sobre el metabolismo oxidativo de cerebro de rata "in vitro"

    OpenAIRE

    Torrecilla García-Ripoll, Juan Ramón

    2012-01-01

    El clorhidrato de tiaprida es una benzamida u ortopramida con efecto neuroléptico atípico. En el presente trabajo se estudia el efecto del clorhidrato de tiaprida sobre el consumo de oxígeno, glucosa, fosforilación oxidativa mitocondrial, actividad ATPasa y la interacción con diversos neurotransmisores en preparaciones de cortes de corteza de rata "in vitro". En relación con el MATERIAL Y METODOS, se determinó el consumo de oxígeno en cortes, homogeneizados y mitocondrias de cerebro de r...

  13. Efecto de Bursera grandiflora sobre el peso corporal y lipemia en ratones obesos

    OpenAIRE

    Lucía AGUILAR SANTAMARÍA; Ofelia ROMERO CERECERO; Manasés GONZÁLEZ CORTAZAR; Tortoriello, Jaime

    2012-01-01

    El sobrepeso y la obesidad están claramente vinculados con la ingesta calórica que lleva a la instalación crónica de inflamación sistémica de bajo grado. La terapia farmacológica es altamente recomendable para este padecimiento. Dentro de la familia Burseraceae existen especies utilizadas para el tratamiento de la obesidad, de las cuales, Bursera grandiflora es referida también por su efecto anti-inflamatorio. Evaluar el efecto de B. grandiflora en un modelo de obesidad, su potencial toxicoló...

  14. EFECTO DEL USO DE Azolla EN LOS RENDIMIENTOS DE CULTIVOS EN CONDICIONES DE ORGANOPÓNICOS

    OpenAIRE

    Castro, R; Maribel Rodríguez; Gloria E. Álvarez; M. Gil; R. Novo; R. I. Castro; Sandra H. Díaz

    2006-01-01

    En el período comprendido entre 1996 y 2001, se realizó el trabajo integrado por dos experimentos, en el organopónico del INRE, Los Palacios, Pinar del Río, con el objetivo de evaluar la influencia de la dosis de Azolla y el efecto residual sobre el rendimiento y la evolución del sustrato de los canteros de los organopónicos con aplicaciones periódicas de este helecho; para ello, se emplearon los cultivos de lechuga y cebollino. En el cultivo de la lechuga se evaluó el efecto de seis dosis de...

  15. Efecto antiinflamatorio preclínico del polvo seco de Caléndula officinalis

    OpenAIRE

    Núñez Figueredo, Yanier; Montero Alarcón, Claudia; Agüero Fernández, Sara; Muñoz Cernuda, Adriana

    2007-01-01

    Para demostrar la actividad antiinflamatoria del polvo seco Caléndula officinalis secado por atomización se emplearon dosis de 50, 150 y 450 mg/Kg y se evaluó el efecto sobre la inflamación aguda provocada por carragenina, dextrán, histamina y serotonina y granuloma inducido por discos de algodón en ratas y edema auricular inducido por aceite de crotón en ratones. El polvo seco mostró efecto inhibitorio sobre los diferentes modelos empleados sin afectar el peso del timo y las glándulas suprar...

  16. Métodos para evaluar el efecto del pastoreo sobre las comunidades vegetales de bofedales

    OpenAIRE

    Mary Carolina Garcia; Rosa Isela Meneses; Kazuya Naoki; Fabien Anthelme

    2014-01-01

    Los bofedales son ecosistemas semi-acuáticos de la zona altoandina dominados por plantas en forma de cojín. Han sido y son usados para el pastoreo desde hace varias generaciones. Los herbívoros son conocidos por afectar la composición y riqueza de las especies en una comunidad vegetal. En bofedales el pastoreo, además de tener un efecto directo sobre la estructura de la comunidad, podría tener un efecto indirecto a través de cambios en las interacciones entre las especies dominantes (plantas ...

  17. Comportamiento geoquimico de las formaciones salinas bajo el efecto de la temperatura y la irradiacion

    OpenAIRE

    Cuevas Müller, Carles de las; Miralles, L; Teixidor, P.; García Veigas, Francisco Javier; Pueyo Mur, Juan José

    1993-01-01

    La generación de defectos cristalinos y la migración de las fases fluidas (salmueras y gases), son los efectos más relevantes de la irradiación y la temperatura sobre una formación salina, susceptible de albergar un almacenamiento de residuos radiactivos. Para determinar dichos efectos se ha puesto a punto la metodología necesaria y se ha verificado sobre muestras salinas de la mina de Sallent (Barcelona). El contenido en agua oscila entre 0,04 y 1 %. Sin embargo, la cantidad de salmuera susc...

  18. Efecto de la amitriptilina sobre la evitación inhibitoria en ratones machos y hembras

    OpenAIRE

    Everss Villalba, Estrella

    2003-01-01

    RESUMEN Los antidepresivos son uno de los posibles tratamientos para prevenir y tratar los síntomas depresivos. Sin embargo, estos fármacos también pueden tener otros efectos no terapéuticos derivados de su acción sobre determinados sistemas de neurotransmisión, por ejemplo, sobre el sistema colinérgico, de gran importancia en los procesos de aprendizaje y memoria. Para mejorar el conocimiento del perfil cognitivo del antidepresivo amitriptilina se investigaron los efectos derivados de su ...

  19. Efecto incretina en el tratamiento de la diabetes mellitus tipo 2

    OpenAIRE

    Manuel de Jesús Díaz Pérez; Jorge Luís Hernández Alfonso; Yareanna Del Rosario Vega

    2015-01-01

    El efecto incretina está dado por las funciones del polipéptido insulinotrópico dependiente de glucosa y un péptido similar a glucagón sobre la hiperglucemia en el organismo humano. Desde su descubrimiento ha cobrado un papel cada vez más significativo en la elaboración de nuevos fármacos normoglucemiantes, que logren el control metabólico de los pacientes con diabetes mellitus tipo 2. El objetivo de esta revisión es actualizar la información sobre el efecto incretina, su relación con la diab...

  20. Aportaciones de la psicología experimental al análisis del efecto placebo

    OpenAIRE

    Ramón Bayés; F. Xavier Borrás

    1993-01-01

    La psicología del aprendizaje ha propuesto un modelo del "efecto placebo" basado en los procesos de condicionamiento clásico. Esta concepción ha recibido soporte empírico del condicionamiento de las respuestas fisiológicas inducidas por drogas. Más recientemente, la psiconeuroinmunología ha demostrado el condicionarnento de las respuestas inmunológicas y su impacto en la salud. Estos datos han ampliado el análisis experimental del efecto placebo como una respuesta condicionada ...

  1. Aportaciones de la psicología experimental al análisis del efecto placebo

    Directory of Open Access Journals (Sweden)

    Ramón Bayés

    1993-01-01

    Full Text Available La psicología del aprendizaje ha propuesto un modelo del "efecto placebo" basado en los procesos de condicionamiento clásico. Esta concepción ha recibido soporte empírico del condicionamiento de las respuestas fisiológicas inducidas por drogas. Más recientemente, la psiconeuroinmunología ha demostrado el condicionarnento de las respuestas inmunológicas y su impacto en la salud. Estos datos han ampliado el análisis experimental del efecto placebo como una respuesta condicionada y sugieren la aplicación del condicionamiento a los tratamientos farmacoterapéuticos.

  2. Efectos del miedo en los trabajadores y la organización

    OpenAIRE

    Cristian Bedoya Dorado; Mónica García Solarte

    2016-01-01

    A partir de la propuesta de Deming sobre erradicar el miedo en el lugar de trabajo, diferentes investigaciones han encontrado que esta emoción es negativa para los trabajadores y las organizaciones. Este artículo tiene como objetivo identificar los efectos que el miedo genera en los trabajadores y en las organizaciones. Para ello, se realizó una revisión bibliográfica sobre los estudios del miedo en la organización y sus implicaciones en el trabajo. De este modo se agruparon los efectos del m...

  3. Efectos del TLCAN en México: una interpretación

    OpenAIRE

    James M. Cypher

    2005-01-01

    No sería posible, creo, ni en un libro extensivo, hacer un balance definitivo de los efectos del TLCAN (Tratado de Libre Comercio de América del Norte) en México. Falta a los economistas de una metodología para separar el resto de la economía mexicana y medir los efectos del TLCAN. No es cosa estática la relación entre los dos. Esto se funda en muchas razones, pero destaca el hecho de que en los últimos 11 años la sociedad mexicana ha sido alterada fundamentalmente por los cambios estructural...

  4. Efectos alelopáticos de rumex crispus l. sobre pissum sativum l

    OpenAIRE

    Moreno B., Luis Francisco

    2012-01-01

    Se investigaron los efectos alelopáticos de R. Crispus sobre P. sativwn mediante 3 ensayos: el primero consistió en incorporar residuos de diferentes partes de la maleza a un cultivo de arveja; los otros dos, en aplicar extractos acuosos y etéricos, en diferentes concentraciones, a semillas de arveja puestas a germinar. El estudio se realizó bajo un diseño completamente al azar en parcelas divididas. El efecto se evaluó mediante la varianza y pruebas de Desviación Standard Media (DSM). Se hal...

  5. Efectos alelopáticos de Rumex Crispus L. sobre Pissum Sativum L

    OpenAIRE

    Moreno B. Luis Francisco

    1989-01-01

    Se investigaron los efectos alelopáticos de R. Crispus sobre P. sativum mediante 3 ensayos: el primero consistió en incorporar residuos de diferentes partes de la maleza a un cultivo de arveja: los otros dos, en aplicar extractos acuosos y etéricos, en diferentes concentraciones, a semillas de arveja puestas a germinar. El estudio se realizó bajo un diseño completamente al azar en parcelas divididas. El efecto se evaluó mediante la varianza y pruebas de Desviación Standard Media (DSM...

  6. Efectos reales de la política fiscal en Colombia: 1990-2007

    OpenAIRE

    Henry Laverde

    2015-01-01

    La evidencia internacional muestra que la actividad económica se veafectada por los choques de la política fiscal. En este trabajo se caracterizan los efectos dinámicos del gasto y los ingresos del Gobierno nacional colombiano sobre el producto interno bruto (PIB) y la demanda agregada para el periodo 1990-2007. Para ello se utiliza un modelo estructural de vectores autorregresivos (SVAR) con información trimestral. Los resultados evidencian los efectos keynesianos tanto de la tributación com...

  7. Stabilizing Plutonium oxide material containing Chloride salts at PFP

    International Nuclear Information System (INIS)

    PFP had over 900 items, weighing more than 1100 kg consisting of impure plutonium oxides referred to as high chloride content plutonium oxides. Tests were conducted to examine items for physical characteristics. After 17 years of storage, the inner food-pack cans maintained integrity with very little evidence of corrosion. Items were washed with water to remove chloride salts. Chloride was readily soluble with plutonium concentrations less than 0.05 g/L in wash solution from all but one of seven items. Washed material was calcined at 1000 C. The calcined material passed the storage test for less than 0.5% water. Unopened items were examined using gamma energy analysis to determine if a prompt gamma (n, x) interaction could be used to screen out items with low chloride concentrations. The prompt gamma was not measurable. A 2168 keV gamma from the (α, x) interaction with chloride correlated within 10% of the chloride concentration measured from washing the item with water

  8. Congenital chloride diarrhea: a review of twelve Arabian children

    Directory of Open Access Journals (Sweden)

    Elrefae F

    2013-06-01

    Full Text Available Fawaz Elrefae,1 Ahmed Farag Elhassanien,2 Hesham Abdel-Aziz Alghiaty3 1Pediatric Gastroenterology, Al-Adan Hospital, Kuwait; 2Faculty of Medicine, Elmansoura University, El Mansoura, El Dakahleya, Egypt; 3Faculty of Medicine, Benha University, Egypt Background: Congenital chloride diarrhea (CCD, a rare autosomal recessive disorder, is characterized by sustained watery diarrhea (due to defect of active Chloride/HCO3 exchange in the ileum and colon with high fecal chloride. Objective: To spotlight the common presentation of CCD for early management and prevention of complications. Subjects and methods: This is a retrospective case series study of patients diagnosed as CCD who were followed up in the pediatric department of Al-Adan Hospital, Kuwait. Results: Twelve patients diagnosed with CCD were born to consanguineous parents; had antenatal history of intrauterine growth retardation (IUGR; polyhydramnios; and distended hypoechoic fetal bowel; and presented with abdominal distension, hypotonia and muscle wasting. 90% of patients had maternal hypertension and 75% of patients had absence of normal meconium at birth. Our patients showed a decrease in serum sodium, potassium, chloride and urine chloride. Conclusion: A high level of suspicion for an early diagnosis of CCD should be considered for any infant presenting with chronic diarrhea, especially in the presence of consanguineous marriage, and the characteristic features in antenatal ultrasound. Thus, allowing for early investigations and appropriate management. Keywords: congenital chloride diarrhea, children, chronic diarrhea, metabolic alkalosis, prenatal diagnosis

  9. Investigation of chloride-release of nuclear grade resin in PWR primary system coolant

    International Nuclear Information System (INIS)

    A new preparation technique is developed for making the low-chloride nuclear-grade resin by commercial resin. The chloride remained in nuclear grade resin may release to PWR primary coolant. The amount of released chloride is depended on the concentration of boron, lithium, other anion impurities, and remained chloride concentration in resin

  10. Ab initio Investigations of the Equilibria between Trichlorothioacetyl Chloride, Tetrachlorothiirane, and Trichloroethenesulfenyl Chloride, their Reactants and Decomposition Products

    DEFF Research Database (Denmark)

    Pedersen, Kim Vestergaard; Christensen, Henrik; Shim, Irene;

    2004-01-01

    Trichlorothioacetyl chloride 1, tetrachlorothiirane 2, and trichloroethenesulfenyl chloride 3 and the equilibria between them have been investigated by ab initio Hartree-Fock (HF), Møller-Plesset second order perturbation (MP2) calculations, and by Gaussian-3 theory, G3(MP2). The transition state...... of the isomerization reactions have been identified. Also investigated were possible reactions leading to the isomers and their possible decomposition products. The results show that the unobserved isomerization reactions are feasible....

  11. A small synthetic molecule functions as a chloride-bicarbonate dual-transporter and induces chloride secretion in cells.

    Science.gov (United States)

    Liu, Peng-Yun; Li, Shing-To; Shen, Fang-Fang; Ko, Wing-Hung; Yao, Xiao-Qiang; Yang, Dan

    2016-05-31

    A C2 symmetric small molecule composed of l-phenylalanine and isophthalamide was found to function as a Cl(-)/HCO3(-) dual transporter and self-assemble into chloride channels. In Ussing-chamber based short-circuit current measurements, this molecule elicited chloride-dependent short-circuit current (Isc) increase in both Calu-3 cell and CFBE41o-cell (with F508del mutant CFTR) monolayers. PMID:27188496

  12. Technical note: Could benzalkonium chloride be a suitable alternative to mercuric chloride for preservation of seawater samples?

    OpenAIRE

    Gloël, J.; Robinson, C.; Tilstone, G. H.; Tarran, G.; J. Kaiser

    2015-01-01

    Instrumental equipment unsuitable or unavailable for fieldwork as well as lack of ship space can necessitate the preservation of seawater samples prior to analysis in a shore-based laboratory. Mercuric chloride (HgCl2) is routinely used for such preservation, but its handling and subsequent disposal incur environmental risks and significant expense. There is therefore a strong motivation to find less hazardous alternatives. Benzalkonium chloride (BAC) has been used previousl...

  13. Technical Note: Could benzalkonium chloride be a suitable alternative to mercuric chloride for preservation of seawater samples?

    OpenAIRE

    Gloël, J.; Robinson, C.; Tilstone, G. H.; Tarran, G.; J. Kaiser

    2015-01-01

    Instrumental equipment unsuitable or unavailable for fieldwork as well as lack of ship space can necessitate the preservation of seawater samples prior to analysis in a shore-based laboratory. Mercuric chloride (HgCl2) is routinely used for such preservation, but its handling and subsequent disposal incur significant risks and expense. Benzalkonium chloride (BAC) has been used previously for freshwater samples. Here, we assess BAC as a less hazardous alterna...

  14. Efectos de la deficiencia de hierro en el funcionamiento intelectual

    Directory of Open Access Journals (Sweden)

    Ernesto Pollitt

    2013-09-01

    Full Text Available El propósito de este trabajo es el de presentar un análisis comparativo de los resultados de seis investigaciones en las cuales ha participado el autor sobre la relación entre la deficiencia de hierro y el funcionamiento intelectual. Las investigaciones fueron realizadas en Egipto, Estados Unidos, Guatemala, Indonesia y Tailandia entre niños de edad pre-escolar. La deficiencia de hierro con anemia está entre las dos deficiencias nutricionales más prevalentes en el mundo y es de esperar que su prevalencia sea alta en el Perú, particularmente entre los infantes y niños y entre las madres gestantes y lactantes. Una de las causas importantes es el limitado consumo de alimentos ricos en hierro hemínico que generalmente son muy costosos para los grupos más pobres de la sociedad. El análisis comparativo muestra que los resultados son consistentes a través de los seis estudios y que la deficiencia de hierro con anemia afecta el rendimiento en las pruebas de procesos cognoscitivos específicos y en las pruebas de rendimiento escolar. Los resultados también muestran que dichos efectos son reversibles con el tratamiento apropiado. A su vez, el análisis muestra que no hay evidencia suficiente para inferir que la deficiencia de hierro sin anemia afecta el cociente intelectual.   The purpose of this paper is to present a comparative analysis of the results of six researches in which the author has participated, about the relation between iron deficiency and intellectual performance. The researches were carried out in Egypt, U.S.A., Guatemala, Indonesia and Thailand, with pre-school and school children. Iron deficiency with anemia are among the two nutritional deficiencies of major prevalence in the word and it must be expected that the same goes for Peru. One of the causes of the low consuming of food rich in iron is that these are too expensive for groups of low socioeconomic level. The comparative analysis shows consistent results in the six

  15. Efecto del calor aportado en recargues nanoestructurados base hierro

    Directory of Open Access Journals (Sweden)

    Agustín Gualco

    2013-12-01

    Full Text Available En los últimos años se han desarrollado consumibles de soldadura que depositan recubrimientos duros de aleaciones base hierro nanoestructuradas de gran resistencia al desgaste abrasivo. Las resistencias al desgaste erosivo y abrasivo están controladas principalmente por la composición química y la microestructura. A su vez, la microestructura del metal depositado puede presentar variaciones con el procedimiento de soldadura empleado, especialmente en relación al aporte térmico. Los parámetros operativos que definen el aporte térmico (tensión, corriente y velocidad de soldadura afectan aspectos como la geometría del cordón (ancho, penetración y sobremonta y la dilución con el material base. El propósito de este trabajo fue estudiar el efecto del calor aportado sobre las características geométricas del cordón, la dilución y la evolución microestructural de una aleación nanoestructurada base hierro, depositada por FCAW. Se soldaron muestras con aportes térmicos de entre 0,5 y 3,5 kJ/mm. Sobre cada cupón soldado se realizó un relevamiento dimensional, se analizó la composición química y se caracterizó la microestructura usando microscopías óptica y electrónica de barrido y difracción de rayos X. También se midieron la microdureza del depósito, el tamaño de cristalita y el grado de dilución. Se observó una gran influencia de las condiciones de proceso sobre la geometría del cordón. La dilución varió entre un 30 y un 40%, la microdureza del depósito se encontró entre 800 y 870 HV1 y el tamaño de cristalita osciló entre 105 y 130 nm, en función de las variables de proceso empleadas. Las mayores durezas y los menores tamaños de cristalita se obtuvieron con el menor aporte térmico, asociado a una menor dilución.

  16. Characterization of the lanthanum chloride scintillation detector

    International Nuclear Information System (INIS)

    This paper reports about the investigations on the performance of the new earth-rare halide Scintillator, the LaCl3:10%Ce, which has been discovered with attractive scintillation properties: fast, efficient, and high-energy resolution. The combination of good brightness and linear response has naturally resulted in a very good energy resolution, whereas the fast decay time promoted counting applications at very high rate and very fast timing resolution. Energy resolutions of (2.99±0.02) %, (8.66±0.02) %, and (2.05±0.01) % have been achieved by exciting the detector with 662 keV 137Cs, 122 keV 152Eu, and 1332.5 keV 60Co sources respectively, at room temperature. The variations of the resolution as a function of both shaping time and high voltage have been studied and found to be relatively linear. The timing resolution was also studied. The value of 1.07 ns FWHM has been recorded with LaCl3:10%Ce and BaF2 detectors operating in coincidence mode, using 1333.5 keV γ-ray 60Co peak. Compared to similar studies, this timing resolution was worse than expected even if the exciting radioactive sources used in the two experiments were different. The efficiency values of (0.24±0.01)%, (0.01±0.01)% and (0.09±0.01)% were obtained with laboratory 137Cs, 152Eu, 60Co isotopes respectively. These detector efficiency values were very low, due to the smaller detector sizes used in these earlier crystals and to the large detector-source-distance used in this experiment. The Lanthanum Chloride Scintillator detector is hygroscopic and relatively expensive compared to established scintillators. In addition, it carries internal contamination in 138La and 227Ac for larger thicknesses. Nevertheless, the energy resolution figures achieved, twice as good as that of NaI(Tl), are in good agreement with those reported elsewhere. They credit the scintillation detectors as good challengers of semiconductor-based detectors, allowing their application fields to be extended. (author)

  17. Effects of Cations on Corrosion of Inconel 625 in Molten Chloride Salts

    Science.gov (United States)

    Zhu, Ming; Ma, Hongfang; Wang, Mingjing; Wang, Zhihua; Sharif, Adel

    2016-04-01

    Hot corrosion of Inconel 625 in sodium chloride, potassium chloride, magnesium chloride, calcium chloride and their mixtures with different compositions is conducted at 900°C to investigate the effects of cations in chloride salts on corrosion behavior of the alloy. XRD, SEM/EDS were used to analyze the compositions, phases, and morphologies of the corrosion products. The results showed that Inconel 625 suffers more severe corrosion in alkaline earth metal chloride molten salts than alkaline metal chloride molten salts. For corrosion in mixture salts, the corrosion rate increased with increasing alkaline earth metal chloride salt content in the mixture. Cations in the chloride molten salts mainly affect the thermal and chemical properties of the salts such as vapor pressure and hydroscopicities, which can affect the basicity of the molten salt. Corrosion of Inconel 625 in alkaline earth metal chloride salts is accelerated with increasing basicity.

  18. Henry’s constant of carbon dioxide-aqueous deep eutectic solvent (choline chloride/ethylene glycol, choline chloride/glycerol, choline chloride/malonic acid) systems

    International Nuclear Information System (INIS)

    Highlights: • A new set of Henry’s constant for the system carbon dioxide-aqueous deep eutectic solvents were measured. • The DESs used were: ethaline, glyceline, and maline. • The measured data were reported as functions of temperature and composition. • The measured data were represented satisfactorily by the applied correlations. -- Abstract: In this study, we present a new set of Henry’s constant data for the system carbon dioxide-aqueous deep eutectic solvent (DES) (20 to 80 wt% DES) at T = (303.15, 308.15, and 313.15) K. The DESs used were choline chloride-based: ethaline (choline chloride/ethylene glycol), glyceline (choline chloride/glycerol), and maline (choline chloride/malonic acid). A differential Henry’s coefficient model was used to describe the behaviour of Henry’s constant, and correlate it with temperature and concentration of DES in the aqueous DES solution. The correlation was found satisfactory such that the proposed model can be used in engineering calculations with reasonable accuracy

  19. Resistance of Alkali-Activated Slag Concrete to Chloride-Induced Corrosion

    OpenAIRE

    Joon Woo Park; Ki Yong Ann; Chang-Geun Cho

    2015-01-01

    The corrosion resistance of steel in alkali-activated slag (AAS) mortar was evaluated by a monitoring of the galvanic current and half-cell potential with time against a chloride-contaminated environment. For chloride transport, rapid chloride penetration test was performed, and chloride binding capacity of AAS was evaluated at a given chloride. The mortar/paste specimens were manufactured with ground granulated blast-furnace slag, instead of Portland cement, and alkali activators were added ...

  20. Simulation of Chloride Diffusion in Cracked Concrete with Different Crack Patterns

    OpenAIRE

    Xiao-Yong Wang; Li-Na Zhang

    2016-01-01

    Chloride-induced corrosion of steel rebar is one of the primary durability problems for reinforced concrete structures in marine environment. Furthermore, if the surfaces of concrete structures have cracks, additional chloride can penetrate into concrete through cracked zone. For chloride ingression into cracked concrete, former researches mainly focus on influence of crack width on chloride diffusion coefficients. Other crack characteristics, such as chloride depth, crack shape (equal-width ...

  1. Efectos del tipo de diabetes, estrategias de afrontamiento, sexo y optimismo en el apoyo social

    OpenAIRE

    Rondón, José E.; Lugli, Zoraide

    2013-01-01

    Se desea conocer el efecto del tipo de diabetes, las estrategias de afrontamiento, el sexo, y el optimismo sobre las redes sociales y el apoyo social percibido por sujetos con diabetes. Participaron 103 hombres y 197 mujeres divididos en diabéticos tipo

  2. Efectos de la drogadicción, el alcoholismo y el tabaquisrno sobre el embarazo

    OpenAIRE

    Chiani de Murad, Margarita E.

    1986-01-01

    Se consideran los posibles efectos nocivos que la adicción a las drogas de uso más frecuente-anialgésicos narcóticos, marihuana, alcohol y tabaco- pueden causar sobre el producto de la concepción.

  3. El cambio climático y sus efectos en el Perú

    OpenAIRE

    Barco, Daniel; Vargas, Paola

    2010-01-01

    Luego de una presentación del impacto esperado del cambio climático en el crecimiento global, analizan las consecuencias del calentamiento y la acumulación de gases de efecto invernadero sobre el crecimiento del país.

  4. Efectos de la Crisis Financiera sobre los Sistemas de pensiones en América Latina

    OpenAIRE

    Mario Marcel; Waldo Tapia Troncoso

    2010-01-01

    Los efectos de la reciente crisis financiera internacional en los fondos de pensiones de América Latina muestran que ésta no solo ha afectado su rentabilidad sino que también la densidad de las cotizaciones como producto del mayor desempleo, informalidad y evasión de aportes a que ha dado lugar la recesión.

  5. Degradation by synergistic effect in synthetic insulators; Degradacion por efecto sinergico en aisladores sinteticos

    Energy Technology Data Exchange (ETDEWEB)

    Garza M, Anibal; Montesinos S, Jose I. [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1991-12-31

    A study is presented of the main degradation phenomena experimented by synthetic insulators and the simultaneous participation of such phenomena to propitiate a synergistic effect. [Espanol] Se presenta un estudio de los principales fenomenos de degradacion que sufren los aisladores sinteticos y la participacion simultanea de dichos fenomenos para propiciar un efecto sinergico.

  6. Efectos del entrenamiento con electroestimulación muscular en pacientes afectados de hemofilia A

    OpenAIRE

    Gomis Bataller, Manuel

    2007-01-01

    RESUMEN La propuesta de la presente investigación fue examinar los efectos producidos por un programa de electroestimulación muscular aplicado sobre el biceps brachii en pacientes afectados de hemofilia A. Treinta sujetos tomaron parte en el presente estudio, 15 pacientes con hemofilia A clínicamente graves (nivel de factor

  7. Cambio climático y efectos sobre la agricultura: la sequía

    OpenAIRE

    Garrido Colmenero, Alberto

    2008-01-01

    •Mitigación del CC: reducción de emisiones de GEI. –Ejemplos: energías renovables/ Agricultura ecológica •Adaptación: estrategias para combatir/atenuar los efectos del CC –Protección en zonas costeras/ Mercados de agua.

  8. Efectos de la aplicación de un plan de trabajo de resistencia y sobrecarga

    OpenAIRE

    Baronetto, Leopoldo Miguel.

    2015-01-01

    En el presente trabajo se propone investigar cuales son los efectos de la aplicación de un Plan de Trabajo de Resistencia y Sobrecarga en la calidad de vida de las personas, apuntando al desarrollo de dos variables fundamentales: la Composición Corporal y el Consumo Máximo de Oxígeno (VO2max).

  9. Efectos del ácido retinoico en el desarrollo temprano del pez cebra Danio rerio

    OpenAIRE

    Carreño Gutiérrez, Héctor

    2009-01-01

    [ES]Este trabajo trata sobre los efectos del ácido retinoico en el desarrollo temprano del pez cebra Danio rerio. [EN]This work deals with the effects of retinoic acid in the early development of zebrafish Danio rerio. Trabajo de Fin de Máster del Máster en Neurociencias, curso 2008-2009.

  10. El efecto knobe: asimetrías en la atribuición de intencionalidad y sus causas

    Directory of Open Access Journals (Sweden)

    Alejandro Rosas

    2013-12-01

    Full Text Available En este artículo proponemos una explicación novedosa del efecto Knobe. El efecto Knobe es una asimetría peculiar en la atribución de intencionalidad a un agente con relación a los efectos colaterales previstos de su acción, dependiendo sólo de la valoración moral del efecto y sin que nada más cambie en la situación juzgada: los efectos colaterales malos, pero no los buenos, se consideran intencionalmente producidos. Nos enfocamos aquí en la pregunta por la explicación de esa peculiar asimetría ¿basta la valencia moral del efecto colateral para explicarla? Hacemos un análisis sistemático de una gran variedad de viñetas presentes en los estudios experimentales y de sus resultados. Intentamos así aislar los factores explicativos. Proponemos que la asimetría se explica por concordancia o discordancia entre la valencia moral del efecto colateral y la actitud moral del agente, juzgada por los espectadores.

  11. Effect of n-tetradecanol on the extraction of iron(III), cobalt(II), and zinc(II) chlorides with tri-n-dodecylammonium chloride

    International Nuclear Information System (INIS)

    Equations are proposed to describe the reduction in the partition coefficients of metal chlorides in amine extractant systems following the addition of alcohols. The equations include two empirical factors: solvation parameters for amine chloride and the compound undergoing extraction. These parameters can be found from independent data. The equations have been used to describe the extraction of micro amounts of iron(III), cobalt(II), and zinc(II) chlorides by tridodecylammonium chloride in the presence of n-tetradecanol

  12. A spectroscopic study of uranium species formed in chloride melts

    International Nuclear Information System (INIS)

    The chlorination of uranium metal or uranium oxides in chloride melts offers an acceptable process for the head-end of pyrochemical reprocessing of spent nuclear fuels. The reactions of uranium metal and ceramic uranium dioxide with chlorine and with hydrogen chloride were studied in the alkali metal chloride melts, NaCl-KCl at 973K, NaCl-CsCl between 873 and 923K and LiCl-KCl at 873K. The uranium species formed therein were characterized from their electronic absorption spectra measured in situ. The kinetic parameters of the reactions depend on melt composition, temperature and chlorinating agent used. The reaction of uranium dioxide with oxygen in the presence of alkali metal chlorides results in the formation of alkali metal uranates. A spectroscopic study, between 723 and 973K, on their formation and their solutions was undertaken in LiCl, LiCl-KCl eutectic and NaCl-CsCl eutectic melts. The dissolution of uranium dioxide in LiCl-KCl eutectic at 923K containing added aluminium trichloride in the presence of oxygen has also been investigated. In this case, the reaction leads to the formation of uranyl chloride species. (author)

  13. VOCl as a Cathode for Rechargeable Chloride Ion Batteries.

    Science.gov (United States)

    Gao, Ping; Reddy, M Anji; Mu, Xiaoke; Diemant, Thomas; Zhang, Le; Zhao-Karger, Zhirong; Chakravadhanula, Venkata Sai Kiran; Clemens, Oliver; Behm, R Jürgen; Fichtner, Maximilian

    2016-03-18

    A novel room temperature rechargeable battery with VOCl cathode, lithium anode, and chloride ion transporting liquid electrolyte is described. The cell is based on the reversible transfer of chloride ions between the two electrodes. The VOCl cathode delivered an initial discharge capacity of 189 mAh g(-1) . A reversible capacity of 113 mAh g(-1) was retained even after 100 cycles when cycled at a high current density of 522 mA g(-1) . Such high cycling stability was achieved in chloride ion batteries for the first time, demonstrating the practicality of the system beyond a proof of concept model. The electrochemical reaction mechanism of the VOCl electrode in the chloride ion cell was investigated in detail by ex situ X-ray diffraction (XRD), infrared spectroscopy (FTIR), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). The results confirm reversible deintercalation-intercalation of chloride ions in the VOCl electrode. PMID:26924132

  14. Interactions between chloride and cement-paste materials.

    Science.gov (United States)

    Barberon, Fabien; Baroghel-Bouny, Véronique; Zanni, Hélène; Bresson, Bruno; d'Espinose de la Caillerie, Jean-Baptiste; Malosse, Lucie; Gan, Zehong

    2005-02-01

    The durability of cement-based materials with respect to exterior aggressions is one of the current priorities in civil engineering. Depending on their use, the cement-based materials can be exposed to different types of aggressive environments. For instance, damages to concrete structures in contact with a saline environment (sea water on bridges, deicing salts on roads, etc.) are of utmost importance. Upon exposure to saline water, Cl- ions penetrate into the structures and subsequently lead to reinforcement corrosion. Chloride attack is often combined with other aggressive influences such as temperature (e.g., freezing) or the ingress of other ions (e.g., sulfates in sea water). We therefore aim to explore the effect of sodium chloride (NaCl) on the structural chemistry of cement paste. Existing studies about reinforcement corrosion by chloride have focused on the penetration of Cl- ions and the comparison between "free" ions (water-soluble ions) and bound ones. However, little is known about the fixation mechanisms, the localization of Cl in the cement matrix and the structural interaction between Cl and the silicate and aluminate hydrate phases present in cement paste. We present here results of a multinuclear nuclear magnetic resonance study on the fixation of chloride in the hydration products and the characterization of new phases potentially appearing due to chloride ingress. PMID:15833625

  15. Bone marrow scintigraphy with 111In-chloride

    International Nuclear Information System (INIS)

    It is assumed that 111In-chloride is bound to serum transferrin and then transported into reticulocyte in erythropoietic marrow. However, several biochemical differences between radioiron and 111In have been reported since these years. In present study, clinical usefulness of 111In-chloride bone marrow scintigraphy was examined especially by comparing 111In-chloride image with sup(99m)Tc-colloid. Obtained results are as follows: 1) In most cases, both 111In-chloride and sup(99m)Tc-colloid images showed similar bone marrow distributions. 2) In three out of 7 cases with hypoplastic anemia and two patients with bone marrow irradiation (700-1,000 rad), the central marrow or irradiated marrow showed marked decreased uptake of 111In, and showed normal uptake of sup(99m)Tc. 3) In two out of 3 cases with chronic myelogenous leucemia, central marrow showed normal uptake of 111In, and showed decreased uptake of sup(99m)Tc. From the present study, the same dissociation findings as those between radioiron and radiocolloid could be obtained in hypoplastic anemia and bone marrow irradiation. 111In-chloride would appear to be a useful erythropoietic imaging agent, although further study of exact comparison with radioiron should be necessary. (auth.)

  16. Efectos de la suplementación con testosterona sobre el rendimiento en resistencia

    Directory of Open Access Journals (Sweden)

    P. Fernández-Díaz

    2016-09-01

    Full Text Available El dopaje en el deporte tiene su origen en la Grecia Clásica. Sin embargo, a lo largo del siglo pasado y hasta la actualidad, la utilización de este tipo de prácticas fraudulentas en el deporte ha ido en aumento. Entre las sustancias dopantes más utilizadas destacan la testosterona y sus derivados sintéticos, los anabolizantes sintéticos. A pesar de que estas sustancias prohibidas se han utilizado para la mejora del rendimiento en pruebas de fuerza y potencia, frecuentemente se detectan positivos en deportistas de resistencia. Los objetivos del presente estudio han sido informar acerca de los efectos ergogénicos de la suplementación con testosterona y anabolizantes sintéticos sobre el rendimiento en resistencia, a través de cambios sobre parámetros sanguíneos, así como los efectos secundarios que tienen sobre la salud. Para ello, se ha realizado una revisión en bases de datos como Elsevier, Medline, Pubmed y Web of Science incluyendo términos como testosterone, anemia, doping, endurance, erythropoietin, hepcidin e iron. La hepcidina se ha propuesto la principal reguladora de las reservas corporales de hierro y la suplementación con testosterona puede afectar a la síntesis de dicha hormona. Los efectos de la testosterona sobre la hepcidina podrían hacer mejorar tanto la capacidad de transporte como de difusión de oxígeno. De este modo, el dopaje con testosterona podría tener un potencial efecto ergogénico en modalidades de resistencia. Sin embargo, dichas mejoras pueden tener efectos negativos sobre el estado de salud del deportista, entre los que se encuentran trastornos metabólicos, orgánicos, psicológicos e inmunosupresión.

  17. Efectos toxicológicos y neuropsiquiátricos producidos por consumo de cocaína

    OpenAIRE

    Téllez Mosquera, Jairo; Cote Menéndez, Miguel

    2014-01-01

    Este artículo realiza una revisión sobre la historia,la cultura, los aspectos clínico toxicológicosy los efectos en el comportamiento producidospor el uso agudo y crónico de la cocaína. Lacocaína como sustancia psicoactiva sin importarsu forma de consumo, una vez dentro delorganismo sigue las mismas vías metabólicas,produciendo efecto sobre los diferentes órganos.La toxicidad de la cocaína es debida a sumetabolito el benzoilecgonina un potente agonistaadrenérgico directo. Los efectos sobre el...

  18. Reformas administrativas y cambio organizacional: hacia el "efecto neto" Administrative Reforms and Organizational Change: Towards the "Net effect"

    OpenAIRE

    David Arellano Gault

    2010-01-01

    En este artículo se discute la idea deque las reformas administrativas sean capaces de transformar y dirigir el comportamiento organizacional directa y linealmente. A partir de ideas clásicas de la sociología y de la sociología las organizaciones se construyen las bases para introducir el concepto del "efecto neto" organizacional. La idea del "efecto neto" es construir reformas administrativas capaces de abarcar y hacerse responsables de los efectos finales de las reformas.This article discus...

  19. Ecología de la conducta urbana y calidad de vida: el efecto ambiental del basural "La Aguada"

    OpenAIRE

    March, Juan Manuel

    2003-01-01

    El objetivo del presente trabajo es determinar e identificar patrones conductuales humanos y sus efectos materiales que conducen al deterioro ecosistémico del ambiente urbano periférico de la ciudad de San Fernando del Valle de Catamarca. Dentro de este plan, se focaliza en un efecto ambiental concreto: la formación de un basural en el Norte de la ciudad y sus efectos adversos sobre la salud humana. La metodología empleada corresponde a la antropología ambiental (aplicación de análisis de eco...

  20. Efectos neuroconductuales derivados de la exposicion a clorpirifos en un modelo animal de la enfermedad de Alzheimer

    OpenAIRE

    Salazar, José Gregorio

    2011-01-01

    El clorpirifos (CPF) es un insecticida organofosforados ampliamente utilizado. Sus efectos neurotóxicos derivan principalmente de la inhibición de colinesterasas. Diferentes investigaciones han indicado efectos conductuales y cognitivos por exposición a CPF. En el presente trabajo, hemos estudiado los efectos neuroconductuales derivados de la exposición a una dosis aguda y dosis repetidas de CPF, en un modelo de ratón transgénico (Tg2576) portador de la mutación Swedish, responsable de una fo...

  1. Evaluation of chemopreventive response of two cycloxygenase-2 inhibitors, etoricoxib and diclofenac in rat colon cancer using FTIR and NMR spectroscopic techniques Evaluación de la respuesta quimiopreventiva de dos inhibidores de la ciclooxigenasa 2, etoricoxib y diclofenaco en el cáncer de colon murino empleando las técnicas espectroscópicas FTIR Y NMR

    Directory of Open Access Journals (Sweden)

    M. Kaur Saini

    2010-08-01

    Full Text Available Non steroidal anti inflammatory drugs (NSAIDs are efficacious in chemoprevention of colorectal cancer. Therefore, the potential ability of Etoricoxib, a selective cycloxygenase-2(COX-2 inhibitor and Diclofenac, a preferential COX-2 inhibitor are considered in the chemoprevention of 1, 2-dimethylhydrazine (DMH induced colon carcinogenesis in rat model. DMH was injected s.c. for six weeks while Etoricoxib and Diclofenac were fed daily orally alone and also in combination with an weekly subcutaneous injection of 1,2-dimethylhydrazine dihydrochloride (DMH to the rats. After the treatment period of 6 weeks the animals were sacrificed by an overdose of ether anesthesia and the colonic tissues were removed and studied by the FTIR and NMR Spectroscopic techniques to evaluate the changes occurring in the lipid bilayer of colonic membrane lipids. The alterations in wave number of FTIR spectra as well as the chemical shifts of NMR spectra were recorded which signify the modulation of membrane lipids during colon carcinogenesis and possible cancer prevention by the oral administration of NSAIDs in an experimental model of chemical induced colon carcinogenesis.Los fármacos antiinflamatorios no esteroideos (AINE son eficaces en la prevención del cáncer colorrectal. Por lo tanto, la capacidad potencial de Etoricoxib, un inhibidor selectivo de la ciclooxigenasa-2(COX-2, y de Diclofenaco, un inhibidor preferencial de la COX-2, se considera en la quimioprevención de la carcinogénesis de colon inducida por 1, 2-dimetilhidracina (DMH en el modelo murino. Se inyectó s.c. DMH durante 6 semanas a la vez que se administraban diariamente por vía oral Etoricoxib y Diclofenaco solos y en combinación con una inyección s.c. semanal de dihidrocloruro de 1,2-dimetilhidracina (DMH a las ratas. Después del período de tratamiento de 6 semanas, se sacrificó a los animales mediante una sobredosis de anestesia con éter y se extirpó el tejido colónico para estudio con

  2. Cystic fibrosis with normal sweat chloride concentration: case report

    Directory of Open Access Journals (Sweden)

    Silva Filho Luiz Vicente Ferreira da

    2003-01-01

    Full Text Available Cystic fibrosis is a genetic disease usually diagnosed by abnormal sweat testing. We report a case of an 18-year-old female with bronchiectasis, chronic P. aeruginosa infection, and normal sweat chloride concentrations who experienced rapid decrease of lung function and clinical deterioration despite treatment. Given the high suspicion ofcystic fibrosis, broad genotyping testing was performed, showing a compound heterozygous with deltaF508 and 3849+10kb C->T mutations, therefore confirming cystic fibrosis diagnosis. Although the sweat chloride test remains the gold standard for the diagnosis of cystic fibrosis, alternative diagnostic tests such as genotyping and electrophysiologic measurements must be performed if there is suspicion of cystic fibrosis, despite normal or borderline sweat chloride levels.

  3. Aluminum chloride restoration of in-situ leached uranium ores

    Energy Technology Data Exchange (ETDEWEB)

    Grant, D.C.; Burgman, H.A.

    1984-01-01

    During in-situ uranium mining using ammonium bicarbonate lixiviant, the ammonium exchanges with cations on the ore's clay. After mining is complete, the ammonium may desorb into post-leach ground water. For the particular ore studied, other elements (uranium and selenium) that are mobilized during the leaching process, have also been found in post-leach ground water. Laboratory column tests, used to simulate the leaching process, have shown that aluminum chloride can rapidly remove ammonium from the ore and, thus, greatly reduce the subsequent ammonium leakage level into ground water. The aluminum chloride has also been found to reduce the leakage levels of uranium and selenium. In addition, the aluminum chloride treatment produces a rapid increase in permeability.

  4. Aluminum chloride restoration of in situ leached uranium ores

    International Nuclear Information System (INIS)

    During in situ uranium mining using ammonium bicarbonate lixiviant, the ammonium exchanges with cations on the ore's clay. After mining is complete, the ammonium may desorb into post-leach ground water. For the particular ore studied, other chemicals (i.e., uranium and selenium) which are mobilized during the leach process, have also been found in the post-leach ground water. Laboratory column tests, used to simulate the leaching process, have shown that aluminum chloride can rapidly remove ammonium from the ore and thus greatly reduce the subsequent ammonium leakage level into ground water. The aluminum chloride has also been found to reduce the leakage levels of uranium and selenium. In addition, the aluminum chloride treatment produces a rapid improvement in permeability

  5. Aluminum chloride restoration of in situ leached uranium ores

    Energy Technology Data Exchange (ETDEWEB)

    Grant, D.C.; Burgman, M.A.

    1982-09-01

    During in situ uranium mining using ammonium bicarbonate lixiviant, the ammonium exchanges with cations on the ore's clay. After mining is complete, the ammonium may desorb into post-leach ground water. For the particular ore studied, other chemicals (i.e., uranium and selenium) which are mobilized during the leach process, have also been found in the post-leach ground water. Laboratory column tests, used to simulate the leaching process, have shown that aluminum chloride can rapidly remove ammonium from the ore and thus greatly reduce the subsequent ammonium leakage level into ground water. The aluminum chloride has also been found to reduce the leakage levels of uranium and selenium. In addition, the aluminum chloride treatment produces a rapid improvement in permeability.

  6. Chloride channels of platelets%血小板氯通道

    Institute of Scientific and Technical Information of China (English)

    陈晓琳; 尹松梅

    2004-01-01

    Chloride channels distribute widely in the body, and participate in many physiological actions and regulatory processes. Based on their physiological roles and molecular structures, six kinds of chloride channels have been identified: (1) The chloride channels family; (2) Cystic fibrosis transmembrane conductance regulator; (3) Swelling-activated chloride channels; (4) Calcium-activated chloride channels; (5) The p64 (CLIC) gene family; (6) γ-aminobutyric acid and glycine receptors. The chloride channels do exist in platelets, and their appearances are dependent on the presence of intracellular calcium. Blocking agents of chloride channels inhibit the thrombin-activated platelet aggregation and the elevation of the intracellular calcium concentration in a dose-dependent manner. It is suggested that chloride channels play a role in the activation of platelets. In addition, chloride channels act on both the cell volume regulation and the intracellular pH regulation in platelets.

  7. Efecto, en un modelo murino, de dos polisacáridos sulfatados sobre la producción de citoquinas por células NK uterinas y de sangre periférica

    Directory of Open Access Journals (Sweden)

    Angela Patricia Cadavid Jaramillo

    2000-02-01

    presenta una estructura química similar a la de la heparina, con la ventaja de presentar efectos anticoagulantes mínimos.

    En este proyecto se trabajará con un modelo murino porque las características de la placentación son similares a las del humano, por la facilidad de su manipulación y, ante todo, por la dificultad para trabajar con muestras de pacientes con abortos electivos ya que en Colombia esta práctica es ilegal. Tampoco es posible trabajar con células procedentes de abortos espontáneos debido a que entran rápidamente en apoptosis, lo cual imposibilita cualquier estudio funcional.

    Este estudio pretende determinar el posible efecto de la heparina y el fucoidan sobre la producción de las citoquinas CSF-1, el factor inhibidor de la leucemia y el interferón gamma, por las células NK uterinas y de sangre periférica en el modelo murino C57BL/6. Se ha elegido trabajar con esta cepa por ser la más utilizada en el estudio de las células NK y por contar con un anticuerpo monoclonal, PK136, que permite identificar poblaciones celulares de alta pureza.

    En el protocolo experimental se utilizarán hembras C57BL/6 sacrificadas a los días 7 a 8 de la gestación, de las cuales se aislarán las células NK uterinas y esplénicas. Luego de un procedimiento de enriquecimiento y purificación se cultivarán con diferentes concentraciones de los polisacáridos sulfatados: heparina de bajo peso molecular y fucoidan; posteriormente se obtendrá el RNA mensajero de las células NK a las 24 horas de cultivo y se someterá a RT-PCR para identificar las citoquinas antes mencionadas. Los productos de la amplificación se correrán en una electroforesis en gel de agarosa y se visualizarán bajo luz ultravioleta después de teñirlas con bromuro de etidio

  8. Antitumor effect of oleic acid; mechanisms of action: A review Efecto antitumoral del ácido oleico; mecanismos de acción: revisión científica

    Directory of Open Access Journals (Sweden)

    C. Carrillo

    2012-12-01

    objetivo recopilar aquellos trabajos que centran su atención en los mecanismos intracelulares que podrían explicar los efectos clínicos atribuidos al ácido oleico. Métodos: Se ha realizado una búsqueda bibliográfica a través de bases de datos electrónicas y las referencias de los artículos de interés han sido utilizadas como fuente de búsquedas más avanzadas. Nuestra revisión se ha centrado en la descripción de dos de las transformaciones celulares que caracterizan el desarrollo de cáncer: proliferación y muerte celular. Resultados: Numerosos estudios atribuyen un papel inhibidor de la proliferación de células tumorales al ácido oleico. Entre los mecanismos de acción, se encuentran su capacidad para suprimir la expresión de HER2 (erbB-2, un oncogén bien conocido por su implicación en la etiología, progresión y metástasis de distintos tipos de cáncer. Además, el ácido oleico podría jugar un papel en la activación de la señalización de calcio intracelular, rutas igualmente ligadas a la proliferación celular. En cuanto a su papel en los fenómenos de muerte celular, el ácido oleico puede inducir apoptosis en células tumorales describiéndose como mecanismos implicados la producción de intracelular de especies reactivas o la activación de la actividad caspasa 3. Aunque muchos estudios relacionan la apoptosis inducida por los ácidos grasos insaturados con la liberación de calcio de los depósitos intracelulares, faltan estudios que aclaren el papel del ácido oleico a este respecto. Conclusión: El ácido oleico juega un papel en la activación de diferentes rutas intracelulares implicadas en el desarrollo de células tumorales. Estos mecanismos podrían ser la base de los efectos protectores que le atribuyen los estudios clínicos.

  9. SiC epitaxy growth using chloride-based CVD

    International Nuclear Information System (INIS)

    The growth of thick epitaxial SiC layers needed for high-voltage, high-power devices is investigated with the chloride-based chemical vapor deposition. High growth rates exceeding 100 μm/h can be obtained, however to obtain device quality epilayers adjustments of the process parameters should be carried out appropriately for the chemistry used. Two different chemistry approaches are compared: addition of hydrogen chloride to the standard precursors or using methyltrichlorosilane, a molecule that contains silicon, carbon and chlorine. Optical and electrical techniques are used to characterize the layers.

  10. Microreactor Technology for On-Site Production of Methyl Chloride

    OpenAIRE

    Schmidt, S A.; Vajglová, Z. (Zuzana); Eränen, K.; Murzin, D.Y.; Salmi, T

    2014-01-01

    A reactor setup consisting of two stainless steel microreactors [gas-phase microreactor (GPMR)-mix from the Institut für Mikrotechnik Mainz (IMM)] coupled in series was used for production of methyl chloride by hydrochlorination of methanol. The catalyst was γ-alumina on microreactor platelets. The influence of temperature on the methanol conversion and methyl chloride selectivity was investigated. A maximum conversion of 97.6% and a selectivity of 98.8% were reached at 340°C, which is c...

  11. Venous uptake of 201Tl as thallous chloride

    International Nuclear Information System (INIS)

    Thallium-201, injected as thallous chloride, has been found to adhere to or be taken up by the vein into which it is injected, permitting images to be obtained of human veins up to 4 h following injection. A digoxin-insensitive rat vein model also retained 201Tl but for shorter periods of time. 201Tl uptake is independent of the solution into which it is introduced, whether 5% dextrose or 0.9% sodium chloride. This technique permits multiple delayed views of normal veins to be obtained but is of uncertain value in the evaluation of thrombophlebitis of the calf because of rather poor resolution and high cost. (author)

  12. Steel corrosion in anoxic mediums with high chloride concentrations

    International Nuclear Information System (INIS)

    Carbon steels are widely used in contact with chloride containing mediums, however most of the literature reports corrosion problems in solutions in contact with air, for example, sea water. There are other applications where the steel is in contact with freshwater in the absence of oxygen as is the case with materials for nuclear repositories or in petroleum production. These mediums can have varied composition but their corrosivity is usually related to the concentration of chlorides. There are no systematic studies in the literature about the influence of high chloride concentrations on the speed of steel corrosion for carbon steels in the absence of oxygen. Some work has been done using Raman and XPS spectroscopy, but these techniques have been carried out ex situ in samples submitted to the action of high chloride concentrations. This results in the appearance of corrosion products on the metal surface due to the oxidation of the surface from exposure to air before and during the use of these techniques, generating confusing and uncertain data. The lack of reliable data is due to the difficulty of applying these techniques in situ under very low oxygen conditions (less than 10 ppb) without allowing any air into the system. Since there are no studies in the literature about the influence of high concentrations of chloride on the corrosion speed of carbon steels in the absence of oxygen, this work aims to generate experimental data to evaluate the influence of high concentrations of this anion on the corrosion speed of steel under anoxic conditions. The corrosivity of each solution was evaluated using electrochemical techniques such as corrosion potential, corrosion speed, anodic and cathodic polarization curves, cyclic voltammetries and electrochemical impedance spectroscopy to study the oxidation-reduction processes that occur with specific temperature, pH and chloride concentration conditions. Concentrated solutions of sodium chloride (50,000, 100,000 and 180

  13. Production and mitigation of acid chlorides in geothermal steam

    Energy Technology Data Exchange (ETDEWEB)

    Simonson, J.M.; Palmer, D.A.

    1995-06-01

    Measurements of the equilibrium distribution of relatively nonvolatile solutes between aqueous liquid and vapor phases have been made at temperatures to 350{degrees}C for HCl(aq) and chloride salts. These data are directly applicable to problems of corrosive-steam production in geothermal steam systems. Compositions of high-temperature brines which could produce steam having given concentrations of chlorides may be estimated at various boiling temperatures. Effects of mitigation methods (e.g., desuperheating) can be calculated based on liquid-vapor equilibrium constants and solute mass balances under vapor-saturation conditions.

  14. An experiment on multibubble sonoluminescence spectra in sodium chloride solution

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhan; XU JunFeng; HUANG Wei; CHEN WeiZhong; MIAO GuoQing

    2008-01-01

    We investigated experimentally the spectra of MBSL in sodium chloride water solution with krypton as dissolved gas. We observed and compared the spectra of hydroxyl ion at 310 nm and that of sodium atom at 589 nm. It has been found that under the same experimental condition, the intensity of sodium atom spectra is obviously higher than that of the hydroxyl ion spectra, and is more sensitive to the experimental condition. The krypton content, the concentration of sodium chloride solution, and the driving sound pressure obviously affect the spectra intensity in certain range.

  15. Stochastic Models for Chloride-Initiated Corrosion in Reinforced Concrete

    DEFF Research Database (Denmark)

    Engelund, S.; Sørensen, John Dalsgaard

    Corrosion of the reinforcement in concrete structures can lead to a substantial decrease of the load-bearing capacity. One mode of corrosion initiation is when the chloride content around the reinforcement exceeds a threshold value. In the present paper a statistical model is developed by which the...... chloride content in a reinforced concrete structure can be predicted. The model parameters are estimated on the basis of measurements. The distribution of the time to initiation of corrosion is estimated by FORM/SORM-analysis....

  16. Evaluación del prohexadione-Ca para el control del crecimiento en manzano: efectos agronómicos y fisiológicos

    OpenAIRE

    Medjdoub, Ratiba

    2003-01-01

    [ES] Existe un delicado balance entre el crecimiento vegetativo y la productividad de los árboles frutales. La alteración de este equilibrio induce a un excesivo crecimiento vegetativo, inversamente relacionado con la calidad del fruto, control de plagas y/ó enfermedades, y rendimiento comercial. Para hacer frente a esta problemática se introdujo el uso de los reguladores del crecimiento vegetativo. Las condiciones cada vez más restrictivas respecto al uso los inhibidores de cr...

  17. Efectos de la terapia combinada del D-004 y el Finasteride sobre la hiperplasia de próstata inducida por testosterona en ratas

    OpenAIRE

    Molina, Vivian; Arruzazabala, María de Lourdes; Carvajal, Daysi; Más, Rosa

    2007-01-01

    La hiperplasia prostática benigna (HPB) es la causa principal de los síntomas molestos del tracto bajo urinario en el hombre adulto. El finasteride, un inhibidor de la enzima 5α-reductasa prostática es un agente terapéutico ampliamente utilizado en la HPB. El D-004, un extracto lipídico obtenido del fruto de Roystonea regia, previene la hiperplasia de próstata inducida con testosterona (T) pero no con dihidrotestosterona (DHT) en roedores. Este estudio fue realizado con el objetivo de ev...

  18. Study of the effect of the NO{sub 2} in the atmospheric corrosion of copper; Estudio del efecto del NO{sub 2} en la corrosion atmosferica del cobre

    Energy Technology Data Exchange (ETDEWEB)

    Mariaca Rodriguez, Liboria

    1997-12-31

    simultanea de SO{sub 2}, a diferentes humedades relativas (HR) y temperaturas del aire atmosferico. Para ello se recurrio a la simulacion de las atmosferas de interes mediante camaras de laboratorio que permitiesen el control de la temperatura, HR y el nivel de contaminacion. En cada atmosfera se expusieron probetas de cobre completamente limpias, que se fueron retirando a los 7, 14, 21 y 28 dias. Se realizaron analisis gravimetricos de ganancia y perdida de masa y una completa caracterizacion de los productos de corrosion formados, principalmente mediante las tecnicas de difraccion de rayos X por angulo rasante (DRS), y espectroscopia fotoelectronica de rayos X (XPS o ESCA). Asimismo, se analizo la aplicabilidad en estas condiciones de las tecnicas electroquimicas de corriente continua (RP, CP y RE) y de corriente alterna (EIE). De los resultados obtenidos cabe senalar como mas importantes los siguientes: La corrosion del cobre en atmosferas contaminadas unicamente con NO{sub 2} depende fundamentalmente de la HR, no existiendo como en el caso de otros metales una HR critica (HRC), a partir de la cual aumenta la cinetica del proceso de corrosion; todo lo contrario, el cobre en este tipo de atmosferas se degrada mas a la menor de las HR ensayadas, 50%, siendo maxima la cinetica a la temperatura de 25 grados Celsius. La proporcion relativa de ambos gases en la mezcla se revela como otro factor de gran interes. Mientras en las atmosferas en que la concentracion de NO{sub 2} no supera la del SO{sub 2}, la mezcla provoca un efecto inhibidor en la corrosion del cobre, en aquellas otras en que la concentracion del NO{sub 2} supera notablemente y la del SO{sub 2} se observa un claro efecto sinergico, poniendose de nuevo de manifiesto los hechos apuntados en el apartado anterior. Las tecnicas instrumentales de ganancia y perdida de masa, complementadas con DRX (angulo rasante) y XPS, se han mostrado muy utiles para el seguimiento, en este tipo de atmosferas, del proceso de corrosion

  19. Uranium(VI) extraction from chloride solution with benzyloctadecyldimethyl ammonium chloride (BODMAC) in a liquid membrane process

    International Nuclear Information System (INIS)

    The recovery of uranium(VI) from chloride solution using a liquid emulsion membrane (LEM) technique was studied. The emulsion is constituted by the quaternary salt of benzyloctadecyldimethyl ammonium chloride (BODMAC, R4NCl) as a carrier, kerosene as organic diluent, Span 80 as emulsifying agent and 0.5 mol/l Na2CO3 as stripping phase. The important variables affecting the LEM permeation process such as the concentrations of extractant, internal strip phase, types of organic diluent, and the presence of magnesium chloride or magnesium sulfate were investigated. It was found that, at a given condition, the maximum extraction rate of uranium(VI) reached 80%. The emulsion was stable at low pH in the presence of certain amounts of electrolytes such as NaCl and MgCl2. (author)

  20. The compatibility of steel and aluminium with calcium chloride/ammonia, magnesium chloride/methylamine and magnesium chloride/methylamine/decane

    International Nuclear Information System (INIS)

    The use of pairs of substances such as calcium chloride/ammonia or magnesium chloride/methylamine for distant heating or heat storage requires compatibility between these substances and the structural materials of the reactor vessels, transport-containers, and/or heat exchangers. Readily weldable mild steel or aluminium are considered likely candidates for the structural materials for transport containers or heat exchangers. In these compatibility investigations the metal samples have been held in contact with the chemical substances under different conditions (temperature, pressure, time) and after the compatibility treatments, the samples were tested. When there is no detectable change in the properties of the samples after the compatibility treatments (in comparison with the as received status) the compatibility is deemed good. Weight changes, surface investigations, fatigue strength tests and metallographical investigations were performed for determining this compatibility. (Auth.)

  1. An electrochemical method for accelerated testing of chloride diffusivity in concrete

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, T.; Gjoerv, O.E. (Norwegian Inst. of Tech., Trondheim (Norway). Div. of Building Materials)

    1994-01-01

    In the present paper an electrochemical method for accelerated testing of chloride diffusivity in concrete is presented. The method is based on a theoretical relationship between chloride diffusivity and observed steady-state rate of chloride migration through the concrete. The concentration of the chloride source solution has a significant influence on the rate of chloride migration and, therefore, a correction factor for ionic interaction in the relationship is introduced. It is shown that the relationship can be used for calculation of chloride diffusivity under various testing conditions. Some experimental results are also presented.

  2. Chloride isolation for accelerator mass spectrometry of 36Cl produced by atomic bomb neutrons

    International Nuclear Information System (INIS)

    Accelerator mass spectrometry was performed at the Munich tandem laboratory to determine the ratio of 36Cl/Cl in silicate rock samples exposed to neutrons of the Hiroshima atomic bomb. Chloride was chemically separated from silicate rock for this purpose. Five grams of silicate rock was fused with 30 g of sodium hydroxide and dissolved in 900 ml of water. The chloride in the resulting solution was spectrophotometrically determined. Chloride was precipitated as silver chloride by addition of appropriate amounts of silver nitrate, and silver chloride was then collected on a membrane filter. The chloride in the rock samples was thus isolated quantitatively. (author)

  3. EFECTO DE BORDE SOBRE EL PROCESO DE DESCOMPOSICIÓN DE HOJARASCA EN BOSQUE NUBLADO

    Directory of Open Access Journals (Sweden)

    Romero-Torres Mauricio

    2011-08-01

    Full Text Available Los fragmentos de bosque son delimitados por bordes y rodeados de matriz circundante. La interacción entre estas comunidades disimiles en estructura y composición, se define como efecto de borde. Este fenómeno genera localmente cambios abióticos y bióticos alterando procesos ecosistémicos del suelo. Para determinar la existencia de este efecto sobre la descomposición de hojarasca y sus factores de control, se seleccionaron dos fragmentos de bosque nublado en la Sabana de Bogotá. Desde los bordes se trazaron transectos con longitud de 64 m y dirección oriente-interior y occidente-interior, donde se dispuso un experimento de descomposición de hojarasca con duración de 90 y 180 días. Allí se estimó el porcentaje de humedad y descomposición de hojarasca, densidad de vegetación, densidad de hongos anamorfos y relación Carbono:Nitrógeno. Se determinó la distancia máxima del efecto de borde y la interacción entre el tiempo de descomposición, orientación y distancia, y se establecieron los factores reguladores de la descomposición. Los resultados mostraron un efecto de la orientación cardinal del borde sobre la descomposición y sobre sus factores reguladores cómo humedad y calidad química. En las zonas de borde oriental se presentó un marcado efecto de borde sobre la humedad de hojarasca hasta los 7 m y sobre la densidad de vegetación hasta los 30 m. En los fragmentos de bosque la descomposición fue regulada por la humedad y relación C:N de la hojarasca. La poca penetración del borde sugiere efectos menores sobre el ciclaje de nutrientes, proporcionando un valor adicional a la conservación de fragmentos pequeños.

  4. The precipitation of radioactive radium-226 from acidic chloride leach liquors with barium chloride

    International Nuclear Information System (INIS)

    The conventional barium chloride (BaClsub(2)) precipitation has been effective in the 99+ percent removal of radium-226 as radium-barium sulphate [RaBa(SOsub(4))sub(2)] sludge, from HCl liquors produced by laboratory and pilot leaches of Canadian uranium ores. Radium-226, due to its low-level radiation characteristics, is removed as it has been identified as an environmental and long-term health problem. The formation of the RaBa(SOsub(4))sub(2) sludge was aided due to adequate sulphate (SOsub(4)) concentrations in the HCl pilot liquors produced. Recyclable Rasup(226) concentrations of about 66 pCi/L, in treated effluents, will cost about 1/10 that of effluents below federal environmental guidelines of 10 pCi Rasup(226)/L. Toxic barium (Ba) will potentially build up in effluents as recyclable Rasup(226) concentrations around 66 pCi/L. Barium, in addition to being added to liquors as BaClsub(2) precipitant, is present in the radioactive ore and HCl leach liquors

  5. El "Efecto Rashomon". Análisis filosófico para el centenario de Akira Kurosawa.

    OpenAIRE

    Mayos Solsona, Gonçal

    2010-01-01

    Antropólogos y epistemólogos llaman "efecto Rashomon" a la subjetividad detectable en la percepción y la memoria, cuando testimonios de un mismo acontecimiento pueden ofrecer relatos o descripciones de éste substancialmente distintos pero, sin embargo, igualmente plausibles. Analizaremos las consecuencias filosóficas del "efecto Rashomon" en la película de Kurosawa que le da nombre y que interpretaremos.

  6. Efecto de la pentoxifilina en la supervivencia, la función cardiaca y en la hemodinámica portal y sistémica de la cirrosis alcohólica avanzada: a randomized double-blind placebo-controlled trial Effect of pentoxiphylline on survival, cardiac function, and portal and systemic hemodynamics in advanced alcoholic cirrhosis

    Directory of Open Access Journals (Sweden)

    C. M. Fernández-Rodríguez

    2008-08-01

    Full Text Available Objetivo: valorar el efecto de la pentoxifilina (un potente inhibidor del factor de necrosis tumoral alfa en la supervivencia, en la hemodinámica sistémica y portal y en la función cardiaca en la cirrosis alcohólica avanzada. Diseño: estudio aleatorizado, doble-ciego, controlado con placebo. Contexto: estudio unicéntrico utilizando grupos de pacientes en paralelo para comparar pentoxifilina y placebo. Pacientes: se incluyeron 24 pacientes con cirrosis alcohólica (8 en estadio B de Child-Pugh y 16 en estadio C de Child-Pugh. Intervención: los pacientes fueron aleatorizados a recibir pentoxifilina (400 mg, 3 veces al día, n = 12 o placebo (n = 12 durante 4 semanas. Determinaciones: el objetivo principal fue la supervivencia a corto/largo plazo. Los objetivos secundarios fueron observar beneficios hemodinámicos (mejoría en la función cardiaca y/o en el índice de resistencias vasculares sistémicas o disminución de la presión portal. Resultados: la presión portal y la función cardiaca no se modificaron y no hubo diferencias en la supervivencia a corto y largo plazo entre los grupos tratados y placebo. Los índices de resistencia vascular sistémica y cardiaco cambiaron en el grupo de pentoxifilina (de 1.721 ± 567 a 2.082 ± 622 Din.seg ¹ cm-5 m-2 y de 4,17 ± 1,4 a 3,4 ± 0,9 lm-2, p = 0,05. Conclusiones: aunque la pentoxifilina parece producir algún beneficio hemodinámico a corto plazo en pacientes con cirrosis alcohólica avanzada, no tiene efecto sobre la tasa de supervivencia, la función cardiaca ni sobre la presión portal en estos pacientes.Objective: to assess the effect of pentoxiphylline (a potent inhibitor of tumor necrosis factor alpha on survival, on systemic and portal hemodynamics, and on cardiac function in patients with alcoholic cirrhosis. Design: a randomized double-blind placebo-controlled trial. Setting: a single center using parallel groups of patients to compare pentoxiphylline with placebo. Patients: we

  7. Effects of non steroidal anti-inflammatory drugs on the antioxidant defense system and the membrane functions in the rat intestine Efectos de los fármacos aniinflamatorios no esteroideos sobre el sistema de defensa antioxidante y las funciones de membrana en el intestino de rata

    Directory of Open Access Journals (Sweden)

    P. Nair

    2006-12-01

    lipids for the treatment groups. These results indicate that celecoxib may be accepted as a safer drug in terms of overall gastro-intestinal toxicity as compared to the aspirin and nimesulide.En el presente estudio se comparaban los efectos de dos inhibidores selectivos de la ciclo-oxigenasa-2 (COX-2, celecoxib y nimesulide, con los de un inhibidor no selectivo de la COX, la aspirina, en el intestino de la rata. Se escogieron ratas Wistar hembra, con un peso de 150-175 g, y se las dividió en 4 grupos, con 8 animales cada uno, como sigue: Grupo 1 (Control, Grupo 2 - Aspirina (40 mg/kg, Grupo 3 - Nimesulide (10 mg/kg, y Grupo 4 - Celecoxib (10 mg/kg. Tras 35 días de tratamiento, se sacrificó a los animales, se extirpó el intestino, y se estudiaron los efectos sobre el sistema de defensa antioxidante, la composición de la membrana y sus funciones, además de las enzimas de membrana específicas, en diferentes regiones del intestino. El estudio mostró un aumento significativo de las concentraciones de peróxido lipídico como sustancia TBA reactiva así como de dienos conjugados, excepto para el grupo tratado con celecoxib que mostró un descenso. También se observó un descenso significativo en las actividades de glutatión reducido (GSH, de superóxido dismutasa (SOD, de glutatión-s-transferasa y de catalasa en los grupos tratados con aspirina y con nimesulide, mientras que el grupo tratado con celecoxib tuvo un aumento de la glutatión reductasa (GR. La aspirina y el nimesulide mostraron un aumento de las actividades de las enzimas ligadas a la membrana de borde en cepillo (BBM como la sucrasa, lactasa, maltasa y fosfatasa alcalina. El contenido en fosfolípidos aumentó sólo en el grupo tratado con aspirina mientras que el colesterol disminuyó en todos los grupos de tratamiento. En el grupo de celecoxib también se objetivó un aumento en el contenido en glucolípidos. Se estudió la fluidez de la membrana mediante difusión rotacional del 1,6-difenil-1

  8. A mathematical model for electrochemical chloride removal from marine cast iron artifacts

    Institute of Scientific and Technical Information of China (English)

    Weizhen OUYANG; Xia CAO; Ning WANG

    2009-01-01

    The aim of this article was to theoretically study diffusion and migration of chlo-ride ions during electrochemical chloride removal. The proposed model would enable optimization of its application by predicting the optimal treatment time and current combination. A mathematical model for simulating the transport behavior of chloride ions was developed by consideration of diffusion and migration of chloride ions when a constant DC current density was applied through the marine cast iron artifacts. The corresponding tests were conducted to validate the mathematical model. This model predicted the data of the extraction ratio of the chloride ion that correlated satisfac-torily with the experimental values. An important issue in electrochemical chloride removal was to understand how chloride ions moved, taking account of diffusion and migration of chloride ions and the release of binding chloride ions. The effects of the treatment time, externally applied current density, chloride diffusion coefficient, and rate constant of release of binding chloride ion on chloride removal are studied. The specific quantitative details applied to one-dimensional model were discussed here. This article has proposed a mathematical model for the first time, which was showed to be a useful tool that can reveal the ionic transport mechanism and optimize the application during electrochemical chloride removal.

  9. Ion exchange in a zeolite-molten chloride system

    International Nuclear Information System (INIS)

    Electrometallurgical treatment of spent nuclear fuel results in a secondary waste stream of radioactive fission products dissolved in chloride salt. Disposal plans include a waste form that can incorporate chloride forms featuring one or more zeolites consolidated with sintered glass. A candidate method for incorporating fission products in the zeolites is passing the contaminated salt over a zeolite column for ion exchange. To date, the molten chloride ion-exchange properties of four zeolites have been investigated for this process: zeolite A, IE95 reg-sign, clinoptilolite, and mordenite. Of these, zeolite A has been the most promising. Treating zeolite 4A, the sodium form of zeolite A , with the solvent salt for the waste stream-lithium-potassium chloride of eutectic melting composition, is expected to provide a material with favorable ion-exchange properties for the treatment of the waste salt. The authors constructed a pilot-plant system for the ion-exchange column. Initial results indicate that there is a direct relationship between the two operating variable of interest, temperature, and initial sodium concentration. Also, the mass ratio has been about 3--5 to bring the sodium concentration of the effluent below 1 mol%

  10. 4-(1H-Tetrazol-5-ylpyridinium chloride

    Directory of Open Access Journals (Sweden)

    Yan-Wei Zhang

    2010-12-01

    Full Text Available In the cation of the title compound, C6H6N5+·Cl−, the tetrazole and pyridine rings are nearly coplanar, making a dihedral angle of 5.58 (11°. The organic cations are linked to the chloride anions via N—H...Cl hydrogen bonds, forming chains along [110].

  11. Reaction of uranium dioxide with copper-containing chloride melts

    International Nuclear Information System (INIS)

    Cermet composition materials consisting of metallic copper and uranium dioxide can be used for manufacturing fuel rods of nuclear power reactors. Reprocessing of such irradiated fuel of dispersive type can be done employing non-aqueous pyrochemical methods and developing such technology requires information on interaction of uranium dioxide with chloride melts containing copper ions

  12. REMOVAL OF CHLORIDE FROM ACIDIC SOLUTIONS USING NO2

    International Nuclear Information System (INIS)

    Chloride (Cl-) salt processing in strong acids is used to recycle plutonium (Pu) from pyrochemical residues. The Savannah River National Laboratory (SRNL) is studying the potential application of nitrogen dioxide (NO2) gas to effectively convert dissolved pyrochemical salt solutions to chloride-free solutions and improve recovery operations. An NO2 sparge has been shown to effectively remove Cl- from solutions containing 6-8 M acid (H+) and up to 5 M Cl-. Chloride removal occurs as a result of the competition of at least two reactions, one which is acid-dependent. Below 4 M H+, NO2 reacts with Cl- to produce nitrosyl chloride (ClNO). Between 6 M and 8 M H+, the reaction of hydrochloric acid (HCl) with nitric acid (HNO3), facilitated by the presence of NO2, strongly affects the rate of Cl- removal. The effect of heating the acidic Cl- salt solution without pre-heating the NO2 gas has minimal effect on Cl- removal rates when the contact times between NO2 and the salt solution are on the order of seconds

  13. Photonic crystal fiber based chloride chemical sensors for corrosion monitoring

    Science.gov (United States)

    Wei, Heming; Tao, Chuanyi; Krishnaswamy, Sridhar

    2016-04-01

    Corrosion of steel is one of the most important durability issues in reinforced concrete (RC) structures because aggressive ions such as chloride ions permeate concrete and corrode steel, consequently accelerating the destruction of structures, especially in marine environments. There are many practical methods for corrosion monitoring in RC structures, mostly focusing on electrochemical-based sensors for monitoring the chloride ion which is thought as one of the most important factors resulting in steel corrosion. In this work, we report a fiber-optic chloride chemical sensor based on long period gratings inscribed in a photonic crystal fiber (PCF) with a chloride sensitive thin film. Numerical simulation is performed to determine the characteristics and resonance spectral response versus the refractive indices of the analyte solution flowing through into the holes in the PCF. The effective refractive index of the cladding mode of the LPGs changes with variations of the analyte solution concentration, resulting in a shift of the resonance wavelength, hence providing the sensor signal. This fiber-optic chemical sensor has a fast response, is easy to prepare and is not susceptible to electromagnetic environment, and can therefore be of use for structural health monitoring of RC structures subjected to such aggressive environments.

  14. Sulfation of Condensed Potassium Chloride by SO2

    DEFF Research Database (Denmark)

    Sengeløv, Louise With; Hansen, Troels Bruun; Bartolomé, Carmen; Wu, Hao; Pedersen, Kim H.; Jappe Frandsen, Flemming; Jensen, Anker Degn; Glarborg, Peter

    2013-01-01

    The interaction between alkali chloride and sulfur oxides has important implications for deposition and corrosion in combustion of biomass. In the present study, the sulfation of particulate KCl (90–125 μm) by SO2 was studied in a fixed bed reactor in the temperature range 673–1023 K and with rea...

  15. Sodium Chloride Dihydrate - A Potential Cause of Slippery Accidents

    DEFF Research Database (Denmark)

    Mejlholm, Morten; Thomsen, Kaj; Rasmussen, Peter;

    From a thermodynamic point of view, it can be expected that sodium chloride dihydrate (hydrohalite, NaCl2H2O) will form on winter roads under certain conditions at temperatures below 0.1¢®C. In order to elucidate whether or not the formation of hydrohalite on the pavement can explain the phenomenon...

  16. Analysis of Yucca Mountain Pore-Water Chloride Data

    International Nuclear Information System (INIS)

    Distribution of chemical constituents in the unsaturated zone (UZ) system of Yucca Mountain, Nevada, depends on many factors, such as hydrological and geochemical processes of surface precipitation, evapotranspiration, the water-fracture-matrix interactions, large-scale mixing via lateral flow and transport, and the history of climate changes. This study analyzes pore-water chloride-concentration data and models the transport processes. The model results are then used to calibrate the UZ flow model with the aim of refining the infiltration distribution and percolation fluxes to the potential repository. The major chemical data used in this study were pore-water chloride (Cl) concentrations. The sensitivity of this conservative tracer to the UZ flow system is well known. This constituent was directly incorporated into a three-dimensional dual-permeability flow model. Chemical transport properties were taken into account. The surface flux of chloride was determined by the total amount of precipitation reaching the surface and chemical concentration in the precipitation. The entire flow system was divided into domains based on the distribution of pore-water chemical data, infiltration data, hydrogeological and hydrostructural features. Model calibration proceeded by adjusting the site-scale infiltration map and anisotropy permeabilities to reach a satisfying agreement between the simulated subsurface chloride distribution and measured data

  17. Electrodeposition of cerium from aqueous cerous chloride solutions

    International Nuclear Information System (INIS)

    Cerium was plated as a grey, metallic, adherent deposit from aqueous cerous chloride baths containing certain organic addition agents. The cathodic current efficiency was determined for each case. Chemical analysis indicates that the purity of the metal is better than 99.0 per cent. (author). 7 refs

  18. Synthesis and characterization of uranium(VI) chloride fluorides

    International Nuclear Information System (INIS)

    Uranium (VI) chloride fluorides were synthesized by the reaction of liquid HCl and solid UF6 between -80 and -114 deg C. These dark red compounds are unstable above -40 to -60 deg C. The simplest formulas derived from compositional analysis are UF5Cl and UF4Cl2. (author)

  19. 21 CFR 862.1170 - Chloride test system.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Chloride test system. 862.1170 Section 862.1170 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES CLINICAL CHEMISTRY AND CLINICAL TOXICOLOGY DEVICES Clinical Chemistry Test Systems §...

  20. Mass-spectrometric investigation of thermochemical properties of lanthanide chlorides

    Energy Technology Data Exchange (ETDEWEB)

    Sapegin, A.M.; Baluev, A.V.; Evdokimov, V.I. (AN SSSR, Chernogolovka. Inst. Novykh Khimicheskikh Problem)

    1984-12-01

    Ionization potentials are measured for ions formed during lanthanide chloride molecules ionization by an electron shock with the use of the improved technique of mass-spectral data processing. Energies of atomization and atomic bond scission in molecules of tri-, di-, and monochlorides are defined along with enthalpies of formation of these molecules in a gaseous state.

  1. Mass-spectrometric investigation of thermochemical properties of lanthanide chlorides

    International Nuclear Information System (INIS)

    Ionization potentials are measured for ions formed during lanthanide chloride molecules ionization by an electron shock with the use of the improved technique of mass-spectral data processing. Energies of atomization and atomic bond scission in molecules of tri-, di-, and monochlorides are defined along with enthalpies of formation of these molecules in a gaseous state

  2. Study on the Reaction Mechanism of Naphthalene with Oxalyl Chloride

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The reaction of naphthalene with oxalyl chloride in the presence of anhydrous AlCl3 was investigated. The homolog of dinaphthyl methanone can be obtained mainly from this reaction. Naphthalene conversion does not have evident correlation with the amount of AlCl3. The results show that the reaction proceeds via carbon cation electrophilic substitution reaction-free radical substitution reaction pathway.

  3. Involvement of chloride in renin secretion from isolated rat glomeruli

    DEFF Research Database (Denmark)

    Skøtt, O; Jensen, B L

    M) inhibited renin release reversibly. Substitution of Cl- with nitrate (101 mM) stimulated renin secretion. Substitution with iodide (15 or 101 mM) had no consistent effect. The stimulation induced by calcium-free solutions was high in May and low in September. In the absence of chloride, the response to...

  4. Polyvinyl chloride catheters with repressed migration of plasticizers

    Czech Academy of Sciences Publication Activity Database

    Sedláček, T.; Polášková, M.; Kašpárková, V.; Filip, Petr; Sáha, P.

    Larnaca : Polymer Processing Society, 2009, s. 243. [Polymer Processing Society Europe/Africa Regional Meeting. Larnaca (GR), 18.10.2009-21.10.2009] Institutional research plan: CEZ:AV0Z20600510 Keywords : Polyvinyl chloride * catheter * repressed migration of plasticizers Subject RIV: BK - Fluid Dynamics

  5. Disposable sensor for electrochemical determination of chloride ions.

    Science.gov (United States)

    Bujes-Garrido, Julia; Arcos-Martínez, M Julia

    2016-08-01

    This work describes the development of a new, simple and inexpensive method for the determination of chloride ions, by using voltammetric disposable sensors. The sensor includes three screen printed electrodes: a working, an auxiliary (both carbon based paste electrodes), and a pseudo-reference Ag/AgCl paste based electrode. Since the presence of chloride ions in the solution modifies the equilibrium potential of Ag/AgCl electrode, the concentration of this analyte has been determined through the systematic shift of the voltammetric peak potential of a control species such as potassium ferricyanide, potassium ferrocyanide or ferrocenemethanol. These control species can be used in solution or mixed into the carbon paste of the working screen printed electrode. In order to characterize the developed methods, reproducibility, repeatability and detection limit of the sensors were calculated in each case. Reproducibility values below 3% (n=5) were obtained. When ferrocenemethanol was used as control species, the lowest quantity of chloride ions detected was 10.0mM. A comprehensive study of interfering ions was also carried out. These sensors were successfully applied to determine the chloride content in sea water and in a commercial saline solution sample. PMID:27216668

  6. (tert-Butyl)(2-hydroxyethyl)ammonium chloride

    OpenAIRE

    Cintya Valerio-Cárdenas; Simón Hernández-Ortega; David Morales-Morales

    2014-01-01

    In the cation of the title molecular salt, C6H16NO+·Cl−, the N—C—C—O torsion angle is 176.5 (2)°. In the crystal, the cations and chloride ions are linked by N—H...O and O—H...O hydrogen bonds, generating a two-dimensional network parallel to (100).

  7. Factors other than chloride level influencing rate of reinforcement

    Energy Technology Data Exchange (ETDEWEB)

    Castel, A.; Arliguie, G. [Paul Sabatier Univ., Toulouse (France); Francois, R. [Institut National Des Sciences Appliques, Toulouse (France)

    2000-07-01

    To evaluate the degree of corrosion a 14 year-old concrete member was completely bared and three meter-long beams were stored in three-point flexion in an aggressive environment by sequences of drying and wetting by a salt fog. Total chloride content was measured at the level of all reinforcements. Despite the small concrete cover of 10 mm at the stirrups and 16 mm for the longitudinal reinforcement, no evidence was found to relate corrosion to chloride content, since a large part of the reinforcement was not affected by corrosion. It was concluded that the steel-concrete interface had a major influence on being able to predict the onset of corrosion in relation to chloride content. Indeed, corrosion damage was only present when the steel-concrete interface was damaged. These results call into question the validity of the chloride threshold as the single determining criterion to forecast corrosion development. It is suggested that the nature of the interface between steel and concrete, which may be randomly distributed along the reinforcements, should also be considered. Experimental evidence shows that steel-concrete interface damage is linked to non-elastic behaviour of bond that occurs at a given level of mechanical loading. Therefore, corrosion damage is best considered as a deterministic phenomenon linked to a bonding damage. 25 refs., 2 tabs., 10 figs.

  8. Aqueous Chloride Operations Overview: Plutonium and Americium Purification/Recovery

    Energy Technology Data Exchange (ETDEWEB)

    Kimball, David Bryan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Skidmore, Bradley Evan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-06-22

    Acqueous Chloride mission is to recover plutonium and americium from pyrochemical residues (undesirable form for utilization and storage) and generate plutonium oxide and americium oxide. Plutonium oxide is recycled into Pu metal production flowsheet. It is suitable for storage. Americium oxide is a valuable product, sold through the DOE-OS isotope sales program.

  9. A chronopotentiometric approach for measuring chloride ion concentration

    NARCIS (Netherlands)

    Abbas, Yawar; Olthuis, Wouter; Berg, van den Albert

    2013-01-01

    In this paper, a novel approach is reported for the electrochemical measurement of chloride ions in aqueous solution. This sensor is based on the stimulus/response principle of chronopotentiometry. A current pulse is applied at the Ag/AgCl working electrode and the potential change is measured with

  10. Preparation of pure uranyl chloride from crude yellow cake

    International Nuclear Information System (INIS)

    A process is described for the preparation of pure uranyl chloride solution from crude yellow cake. The process involves dissolution of the latter in hydrochloric acid followed by uranium extraction using TBP-kerosene mixture. A series of experiments were carried out in order to determine the optimum conditions for both the dissolution and the extraction steps

  11. 21 CFR 184.1845 - Stannous chloride (anhydrous and dihydrated).

    Science.gov (United States)

    2010-04-01

    .... (b) Both forms of the ingredient meet the specifications of the Food Chemicals Codex, 3d Ed. (1981... 21 Food and Drugs 3 2010-04-01 2009-04-01 true Stannous chloride (anhydrous and dihydrated). 184.1845 Section 184.1845 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND...

  12. Application and comparison of cocrystallization techniques on trospium chloride cocrystals

    Czech Academy of Sciences Publication Activity Database

    Sládková, V.; Cibulková, J.; Eigner, V.; Šturc, A.; Kratochvíl, B.; Rohlíček, Jan

    2014-01-01

    Roč. 14, č. 6 (2014), s. 2931-2936. ISSN 1528-7483 Institutional support: RVO:68378271 Keywords : cocrystal * cocrystallization methods * x-ray diffraction * x-ray powder diffraction * trospium chloride Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 4.891, year: 2014

  13. El efecto Harrod-Balassa-Samuelson. El caso de México

    Directory of Open Access Journals (Sweden)

    Mario Gómez Aguirre

    2013-01-01

    Full Text Available En este artículo se analiza el efecto Harrod-Balassa-Samuelson (HBS para el caso de México durante el periodo 1970-2009. Para ello se utiliza un modelo econométrico que incorpora la presencia de cambios estructurales. Los resultados alcanzados en esta investigación sugieren que no se cumple el efecto HBS entre México y Estados Unidos durante este periodo y, por lo tanto, no se corrobora estadísticamente que las diferentes tasas de crecimiento de la productividad de los bienes comerciables y no comerciables entre ambos países hayan afectado al tipo de cambio real.

  14. Efectos ecológicos del fenómeno ENOS en Colombia

    OpenAIRE

    Yesid Carvajal; Henry Jiménez; Hernán Materón

    2014-01-01

    El fenómeno ENOS, tiene un sustancial efecto sobre las variaciones del clima a nivel mundial; por lo tanto, no sorprende que sus efectos tengan un impacto ecológico y socioeconómico fuerte, alterando la seguridad alimentaria de los países a nivel mundial. Ante este panorama, es comprensible que haya despertado el mayor interés mundial, no sólo en los especialistas en meteorología y oceanografía sino también entre biólogos, ecólogos, físicos, matemáticos, agrónomos, hidrólogos, economistas, so...

  15. Barium borohydride chlorides: synthesis, crystal structures and thermal properties.

    Science.gov (United States)

    Grube, Elisabeth; Olesen, Cathrine H; Ravnsbæk, Dorthe B; Jensen, Torben R

    2016-05-10

    Here we report the synthesis, mechanism of formation, characterization and thermal decomposition of new barium borohydride chlorides prepared by mechanochemistry and thermal treatment of MBH4-BaCl2, M = Li, Na or K in ratios 1 : 1 and 1 : 2. Initially, orthorhombic barium chloride, o-BaCl2 transforms into o-Ba(BH4)xCl2-x, x ∼ 0.15. Excess LiBH4 leads to continued anion substitution and a phase transformation into hexagonal barium borohydride chloride h-Ba(BH4)xCl2-x, which accommodates higher amounts of borohydride, possibly x ∼ 0.85 and resembles h-BaCl2. Thus, two solid solutions are in equilibrium during mechano-chemical treatment of LiBH4-BaCl2 (1 : 1) whereas LiBH4-BaCl2 (2 : 1) converts to h-Ba(BH4)0.85Cl1.15. Upon thermal treatment at T > ∼200 °C, h-Ba(BH4)0.85Cl1.15 transforms into another orthorhombic barium borohydride chloride compound, o-Ba(BH4)0.85Cl1.15, which is structurally similar to o-BaBr2. The samples with M = Na and K have lower reactivity and form o-Ba(BH4)xCl2-x, x ∼ 0.1 and a solid solution of sodium chloride dissolved in solid sodium borohydride, Na(BH4)1-xClx, x = 0.07. The new compounds and reaction mechanisms are investigated by in situ synchrotron radiation powder X-ray diffraction (SR-PXD), Fourier transform infrared spectroscopy (FT-IR) and simultaneous thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), mass spectroscopy (MS) and temperature programmed photographic analysis (TPPA). PMID:27109871

  16. Chloride channels and the reactions of cells to topography

    Directory of Open Access Journals (Sweden)

    Tobasnick G.

    2001-12-01

    Full Text Available The reactions of rat epitenon cells to substratum topography on the micrometric and nanometric scale such as groove-ridge structures include cell extension, elongation and orientation reactions. In this paper we report that stretch-sensitive chloride channels may be involved in the earliest stages of these reactions in epitenon fibroblast-like cells. We report that rat epitenon-cells can develop appreciable lateral mechanical tension that could stretch both the force generating cells themselves and those nearby. We show that cells in medium in which more than 80% of the chloride has been replaced by nitrate show little reaction to topography. Spreading of the cells takes place but is much reduced along the direction of the groove-ridge topography but enhanced across the topography. The chloride channel inhibitors NPPB (5-Nitro-2- (3phenylpropylamino benzoicacid 4,4'-disothiocyanostilbene-2, 2' sulphonic acid (DIDS and Chlorotoxin produce similar results which are further accentuated when these inhibitors are presented in low chloride medium. An antibody against ClC3, which has close homology to ClC5/6 also, blocked reaction to topography. These treatments have no significant effect on cell spreading on planar surfaces nor do they lead to changes in internal pH in the cells. There is a slight inhibition of rates of cell movement . Experiments using antisense oligoribonucleotides to ClC-5 or ClC-6 channel m-RNA also inhibit topographic reactions, which provides further confirmation of the hypothesis. Since the ClC-3,4 and 5 share considerable sequence similarities in the genes and in their proteins it has not been possible to make an unambigous determination of which precise chloride channel(s is (are involved.

  17. Efecto antifúngico de un extracto de Petiveria alliacea L.

    OpenAIRE

    Illnait-Zaragozí, María T.; José Illnait-Ferrer; Armando Blanco-García

    2010-01-01

    La utilidad de Petiveria alliacea L. como agente antimicrobiano ha sido reportada por diferentes autores. Sin embargo, su actividad como antimicótico ha sido poco estudiada. El objetivo del presente estudio fue constatar el efecto antifúngico in vitro de un extracto hidroalcohólico de esta planta (EHAPAL) en 11 cepas de levaduras. (Candida albicans ATCC 64548 y ATCC 64550, C. krusei ATCC 6258, C. glabrata ATCC 90030, C. lusitaniae ATCC 200951, C. parapsilosis ATCC 22019, Saccharomyces cerevis...

  18. Emprendimiento por necesidad y por oportunidad: el efecto mediador de la cultura

    OpenAIRE

    Liñán Alcalde, Francisco; Fernández Serrano, José; Romero, Isidoro

    2013-01-01

    Este trabajo estudia el efecto mediador de los valores culturales sobre la actividad emprendedora total (TEA) y la motivación de los emprendedores -diferenciando el motivo oportunidad frente al motivo necesidad- en países con niveles diferentes de desarrollo. Los datos de 56 países del Global Entrepreneurship Monitor (GEM) sobre actividad emprendedora y de la Schwartz Value Survey (1994, 2006b) se analizan usando modelos de ecuaciones estructurales. Los resultados muestran q...

  19. Cognitive effects of antiepileptic drugs Efectos cognitivos de los medicamentos antiepilépticos

    Directory of Open Access Journals (Sweden)

    Jaime Carrizosa Moog

    2009-11-01

    Full Text Available

    Antiepileptic drugs have psychotropic and cognitive effects, either positive or negative, in some patients. The impact of these effects may be very important in epileptic subjects, especially during childhood and in the elderly. The diversity of methodological designs, of population samples, of doses and therapeutic levels makes it difficult to interpret these effects. In this article the effects of antiepileptic drugs, both traditional and novel, are reviewed on the basis of different studies in both animals and human beings.

    Los medicamentos antiepilépticos tienen efectos cognitivos y psicotrópicos, que en determinados pacientes pueden influir en el desempeño positivo o negativo. El impacto de estos efectos es muy importante en la población con epilepsia, fundamentalmente en edades de cuidado como la infancia y la ancianidad. La diversidad de diseños metodológicos, de muestras poblacionales, de dosificaciones y niveles terapéuticos hace que sea difícil la interpretación de estos efectos. Se revisan los efectos de los fármacos antiepilépticos corrientes y de los nuevos en diferentes estudios en animales y en seres humanos.

  20. Efecto de las enhancinas sobre las propiedades insecticidas de los baculovirus

    OpenAIRE

    Aguirre Sánchez, Eduardo

    2014-01-01

    El objetivo del presente trabajo fue caracterizar molecularmente una enhancina (VEF, virus enhancing factor) localizada en el genoma de un granulovirus de Agrotis segetum (AgseGV) aislado en Badajoz y determinar su efecto sobre la actividad insecticida del Alphabaculovirus de Autographa californica (AcMNPV) para distintas especies de insectos susceptibles. La enhancina de AgseGV presentó un 99% de identidad con la enhancina de otro aislado del AgseGV de China (AY522332) mientra...

  1. EFECTO DE LA ACUPUNTURA EN EL MANEJO INTEGRAL DE LA ADICCION AL TABACO

    OpenAIRE

    GOVANTES LORA, MARIA CRISTINA

    2010-01-01

    EL TABAQUISMO CONSTITUYE LA CAUSA NUMERO UNO DE ENFERMEDAD Y MUERTE PREMATURA, E INCREMENTA EL RIESGO A PRESENTAR CANCER PULMONAR EN UN 90 POR CIENTO. LAS METAS QUE PERSIGUE EL TRATAMIENTO DE LAS PERSONAS ADICTAS AL TABACO SE CENTRA EN TRES ASPECTOS: DESINTOXICACION, TRATAMIENTO DE LA ABSTINENCIA Y LA PREVENCION DE LA REINCIDENCIA DEL HABITO. EN EL PRESENTE ENSAYO CLINICO CONTROLADO, SE ESTUDIO EL EFECTO DE LA ACUPUNTURA ASOCIADO A UNA TERAPIA COGNITIVA CONDUCTUAL EN PACIENTES QUE ACUDIERON A...

  2. Efecto de la aplicación de mezclas de abono organomineral en el cultivo del maíz (Zea mays L. sobre un suelo pardo sialítico mullido no carbonatado.

    Directory of Open Access Journals (Sweden)

    Pável Chaveli Chávez

    2013-04-01

    Full Text Available RESUMEN Se realizó un estudio para comprobar el efecto de varias mezclas de abonos organominerales sobre el cultivo del maíz en un suelo Pardo sialítico mullido no carbonatado. Se utilizaron cinco diferentes mezclas utilizando como abonos orgánicos el estiércol vacuno composteado; cachaza y como portadores minerales urea, superfosfato triple y cloruro de potasio. Además se tomaron muestras de suelo con el objetivo de medir el efecto que produce la utilización de este abono sobre las principales propiedades del mismo. Se obtuvo que la fertilización organomineral favorece la producción de maíz, manteniendo el rendimiento y la calidad del fruto con respecto a la fertilización mineral tradicional; de igual forma no deteriora las condiciones del suelo para el mejor desarrollo del cultivo. EFFECT OF FERTILIZER APPLICATION OF MIXED ORGANOMINERAL GROWING CORN (Zea mays ON BROWN SIALYTIC FLUFFY NONCARBONATED SOIL. ABSTRACT. A study was conducted to test the effect of various mixtures of organo-fertilizers on maize in a fluffy Sialytic Brown noncarbonated soil. Five different mixtures were used as organic fertilizers using the composted cow manure, press mud as carrier minerals and urea, triple superphosphate and potassium chloride. In addition soil samples were taken in order to measure the effect of the use of this fertilizer on major properties. It was found that the organo-fertilization favors the production of corn, maintaining performance and fruit quality compared to traditional mineral fertilization, and likewise does not deteriorate the soil conditions for better crop development.

  3. Properties of a conductive cellular chloride pathway in the skin of the toad (Bufo bufo)

    DEFF Research Database (Denmark)

    Larsen, Erik Hviid; Kristensen, P

    1978-01-01

    -compartment model indicate that the strong steady-state chloride current rectification cannot be obtained if only the intracellular chloride concentration and the membrane potentials are allowed to vary ("Goldman-rectification"). It is suggested, therefore, that the premeability of the chloride pathway varies...... steady-state conductance and the steady-state chloride current reveal that the chloride pathway has maximum conductance for V approximately -80 mV (outside of the skin being negative) and approaches a non-conducting safe for V greater than 0 mV. This strong outward going rectification is a steady......-state phenomenon: In skins hyperpolarized for a few minutes, the "instantaneous" I-V curves show that the chloride pathway in the conducting state allows a large inward chloride current (outward chloride flux) to pass in the voltage range 40 mV greater than V greater than 0 mV. Calculations based on a three...

  4. The chloride channel inhibitor NS3736 [corrected] prevents bone resorption in ovariectomized rats without changing bone formation

    DEFF Research Database (Denmark)

    Schaller, Sophie; Henriksen, Kim; Sveigaard, Christina;

    2004-01-01

    Chloride channel activity is essential for osteoclast function. Consequently, inhibition of the osteoclastic chloride channel should prevent bone resorption. Accordingly, we tested a chloride channel inhibitor on bone turnover and found that it inhibits bone resorption without affecting bone form...

  5. Efectos de la competencia del terapeuta en el tratamiento de adolescentes con fobia social generalizada

    Directory of Open Access Journals (Sweden)

    Pablo J. Olivares-Olivares

    2015-01-01

    Full Text Available El propósito de este estudio es verificar la parte de los resultados del Programa para la Intervención en Adolescentes con Fobia Social que puede ser atribuida a la competencia del terapeuta. Se presentan los resultados obtenidos en tres condiciones experimentales (grupos experto, cuasi-experto e inexperto, integradas por 46 adolescentes españoles con una edad media de 15.37 años (DT = 1.04; rango = 14-18, siendo la mayoría chicas (67.40% que cursaban 4º de E.S.O (46.70%. Todos cumplieron los criterios requeridos para el diagnóstico de Fobia Social Generalizada. Los resultados muestran que (i el tamaño del efecto que se puede atribuir a los terapeutas es bajo, (ii que la magnitud del tamaño del efecto obtenido correlaciona con la magnitud de la competencia del terapeuta en las variables más sensibles al cambio terapéutico, (iii que tales resultados no alcanzan diferencias con significación estadística entre las tres condiciones experimentales. Los datos hallados nos permiten concluir que siendo relevante el impacto de la competencia del terapeuta en los resultados obtenidos la mayor parte de la varianza en los resultados se relaciona directamente con el efecto del programa de tratamiento manualizado que se ha aplicado.

  6. Innovaciones organizacionales y su efecto sobre el desempeño empresarial

    Directory of Open Access Journals (Sweden)

    Sergio M. Afcha Chávez

    2011-01-01

    Full Text Available A diferencia de las innovaciones tecnológicas la literatura que analiza la adopción y los efectos de las innovaciones organizacionales es relativamente escasa. Este hecho, obedece a las dificultades de conceptualización y medición de este concepto. Utilizando los datos del Panel de Innovación Tecnológica (PITEC se analizan los factores que influyen en la adopción de innovaciones organizacionales, así como su efecto sobre distintas variables del desempeño empresarial, para ello se estima un modelo probit trivariante, mediante la aplicación del método máxima verosimilitud simulado, el cual, incorpora la simulación de Geweke-Hajivassiliou-Keane (GHK. Los resultados ponen de manifiesto la interdependencia entre los distintos tipos de innovaciones organizacionales y la necesidad de controlar esta interacción. Por otra parte, el análisis del efecto de las innovaciones organizacionales, permite concluir que aquellas relacionadas con la organización del trabajo son las que generan un mayor impacto sobre el desempeño empresarial.

  7. El efecto de las remesas familiares en el bienestar de los hogares guatemaltecos

    Directory of Open Access Journals (Sweden)

    Sibyl Italia Pineda Salazar

    2008-08-01

    Full Text Available EL PRESENTE ESTUDIO TIENE COMO OBJETIVO MEDIR EL EFECTO QUE HAN tenido las remesas familiares en el bienestar de los hogares guatemaltecos. El análisis se realizó a través de los datos proporcionados por el Instituto Nacional de Estadística (INEen su Encuesta Nacional de Condiciones de Vida (ENCOVI del año 2006.Para determinar el efecto que tienen estos flujos, se aplicó un modelo econométrico1 planteado por Adams (2004 que utiliza el Agregado de Consumo como medida de bienestar.En base a las estimaciones derivadas, se logró determinar que las remesas familiares han generado una disminución en la incidencia, la brecha y severidad de la pobreza en el país. Asimismo, se estimó que estos flujos son fundamentales para financiar los servicios educativos y atención en salud de los hogares receptores. Por lo tanto, las remesas recibidas por los hogares guatemaltecos nosolamente tienen un efecto positivo en el bienestar desde la perspectiva del gasto, sino que también generan retornos sobre la inversión en capital humano.

  8. Efecto del burnout y la sobrecarga en la calidad de vida en el trabajo

    Directory of Open Access Journals (Sweden)

    Juana Patlán Pérez

    2013-01-01

    Full Text Available El síndrome de burnout se presenta con frecuencia en trabajadores que tienen contacto con usuarios o clientes. El artículo tiene como objetivo determinar el efecto del burnout y la sobrecarga en la calidad de vida en el trabajo en personal de un instituto de salud en México. La metodología de investigación fue expostfacto y descriptiva con una muestra estratificada de 673 trabajadores. Se utilizaron 4 escalas para medir sobrecarga de trabajo, burnout y 2 factores de calidad de vida en el trabajo: conflicto trabajo-familia y satisfacción laboral. Los resultados indican un efecto positivo y significativo de la sobrecarga en el burnout y el conflicto trabajo-familia, y un efecto negativo de la sobrecarga en la satisfacción laboral. Además, el burnout está asociado de forma positiva al conflicto trabajo-familia y negativa a la satisfacción laboral.

  9. SEPARATION OF MAGNESIUM CHLORIDE FROM SEA WATER BY PREFERENTIAL SALT SEPARATION (PSS)

    OpenAIRE

    Khaled Zohdy, Maha Abdel Kareem and Hussein Abdel-Aal*

    2013-01-01

    Magnesium chloride is typically extracted from sea water on an industrial scale by precipitating it as magnesium hydroxide, then converting it to the chloride by adding hydrochloric acid. This process is known as the Dow process which uses the chemical approach in producing magnesium chloride. Kettani and Abdel-Aal [1], proposed a physical separation procedure known as the Preferential Salt Separation (PSS) to obtain magnesium chloride directly from sea water. In principle, the PSS concept is...

  10. ENHANCEMENT OF CHLORIDE RESISTANCE OF PRE-STRESSED CONCRETE SHEET PILE BY BLAST FURNACE SLAG

    OpenAIRE

    Irmawaty, Rita

    2012-01-01

    Chloride-induced corrosion is one of the main mechanisms of deterioration affecting the long-term performance of concrete structures. In Japan, a large majority of structures are built either near the costal or indirect contact with seawater. The durability of reinforced or pre-stressed concrete structure depends on the resistance of concrete to chloride penetration. Naturally concrete provides physical and chemical protection to the reinforcing steel from chloride penetrating. The chloride ...

  11. Higher serum chloride concentrations are associated with acute kidney injury in unselected critically ill patients

    OpenAIRE

    Zhang, Zhongheng; Xu, Xiao; Fan, Haozhe; Li, Danyu; Deng, Hongsheng

    2013-01-01

    Background Chloride administration has been found to be harmful to the kidney in critically ill patients. However the association between plasma chloride concentration and renal function has never been investigated. Methods This was a retrospective study conducted in a tertiary 24-bed intensive care unit from September 2010 to November 2012. Data on serum chloride for each patient during their ICU stay were abstracted from electronic database. Cl0 referred to the initial chloride on ICU entry...

  12. Cytogenetic Effects of Copper Chloride on the Root Tip Cells of Helianthus annuus L.

    OpenAIRE

    İNCEER, Hüseyin; AYAZ, Sema; BEYAZOĞLU, Osman; ŞENTÜRK, Emine

    2003-01-01

    The cytogenetic effects of copper chloride on root tip cells of Helianthus annuus were investigated. Seeds were treated with 10, 25, 50 and 100 mg/L (ppm) of copper chloride for 24 h. It was found that copper chloride has a marked mitodepressive action on mitosis. Mitotic abnormalities were increased and the mitotic index was decreased depending on the concentration of the copper chloride applied.

  13. [Activity of Ca(2+)-dependent neutral proteinases in rat organs under cobalt and mercury chloride injection].

    Science.gov (United States)

    Kaliman, P A; Samokhin, A A; Samokhina, L M

    2003-01-01

    The activity of Ca(2+)-dependent neutral proteinases in rats under cobalt and mercury chloride injection was investigated. The calpains activity increase in the lungs, heart, liver and kidneys was revealed after 2 h cobalt chloride action. The mercury chloride gives a reliable increase of calcium-dependent neutral proteinases only in the kidneys. PMID:14574747

  14. 40 CFR 721.10154 - Quaternary ammonium compounds, dicoco alkyldimethyl, chlorides, reaction products with silica.

    Science.gov (United States)

    2010-07-01

    ... alkyldimethyl, chlorides, reaction products with silica. 721.10154 Section 721.10154 Protection of Environment..., dicoco alkyldimethyl, chlorides, reaction products with silica. (a) Chemical substance and significant..., dicoco alkyldimethyl, chlorides, reaction products with silica (PMN P-08-157; CAS No. 956147-76-5)...

  15. 46 CFR 154.1750 - Butadiene or vinyl chloride: Refrigeration system.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Butadiene or vinyl chloride: Refrigeration system. 154... and Operating Requirements § 154.1750 Butadiene or vinyl chloride: Refrigeration system. A refrigeration system for butadiene or vinyl chloride must not use vapor compression unless it: (a) Avoids...

  16. Enthalpic interactions of N-glycylglycine with xylitol in aqueous sodium chloride and potassium chloride solutions at T = 298.15 K

    International Nuclear Information System (INIS)

    The mixing enthalpies of N-glycylglycine with xylitol and their respective enthalpies of dilution in aqueous sodium chloride and potassium chloride solutions have been determined by using flow-mix isothermal microcalorimetry at the temperature of 298.15 K. These experimental results have been used to determine the heterotactic enthalpic interaction coefficients (hxy, hxxy, and hxyy) according to the McMillan-Mayer theory. It has been found that the heterotactic enthalpic pairwise interaction coefficients hxy between N-glycylglycine and xylitol in aqueous sodium chloride and potassium chloride solutions are negative and become less negative with an increase in the molality of sodium chloride or potassium chloride. The results are discussed in terms of solute-solute and solute-solvent interactions.

  17. Enthalpic interactions of N-glycylglycine with xylitol in aqueous sodium chloride and potassium chloride solutions at T = 298.15 K

    Energy Technology Data Exchange (ETDEWEB)

    Liu Min, E-mail: panpanliumin@163.co [College of Chemistry and Chemical Engineering, Liao Cheng University, Liaocheng, Shandong 252059 (China); Wang Lili [College of Chemistry and Chemical Engineering, Liao Cheng University, Liaocheng, Shandong 252059 (China); Zhu Lanying [College of Life Science and Bioengineering, Liao Cheng University, Liaocheng, Shandong 252059 (China); Li Hui; Sun Dezhi; Di Youying; Li Linwei [College of Chemistry and Chemical Engineering, Liao Cheng University, Liaocheng, Shandong 252059 (China)

    2010-07-15

    The mixing enthalpies of N-glycylglycine with xylitol and their respective enthalpies of dilution in aqueous sodium chloride and potassium chloride solutions have been determined by using flow-mix isothermal microcalorimetry at the temperature of 298.15 K. These experimental results have been used to determine the heterotactic enthalpic interaction coefficients (h{sub xy}, h{sub xxy}, and h{sub xyy}) according to the McMillan-Mayer theory. It has been found that the heterotactic enthalpic pairwise interaction coefficients h{sub xy} between N-glycylglycine and xylitol in aqueous sodium chloride and potassium chloride solutions are negative and become less negative with an increase in the molality of sodium chloride or potassium chloride. The results are discussed in terms of solute-solute and solute-solvent interactions.

  18. Effect of etoricoxib, a cyclooxygenase-2 selective inhibitor on aberrant crypt formation and apoptosis in 1,2 dimethyl hydrazine induced colon carcinogenesis in rat model Efecto del etoricoxib, un inhibidor selectivo de la ciclooxigenasa-2, sobre la formación de criptas aberrantes y la apoptosis en un modelo murino de carcinogénesis de colon inducidad por 1,2-dimetilhidracina

    OpenAIRE

    Sharma, P.; J Kaur; S. N. Sanyal

    2010-01-01

    Etoricoxib, a second generation selective cyclooxygenase-2 (COX-2) inhibitor had been studied for the chemopreventive response at its therapeutic anti-inflammatory dose in 1,2-dimethylhydrazine (DMH) induced colon carcinogenesis in rat model. Eight to ten weeks old male rats of Sprague-Dawley strain were divided into four groups. While group 1 served as control and received the vehicle of the drugs, group 2 and 3 were administered freshly prepared DMH in 1mM EDTA-saline (pH 7.0) (30 mg/kg bod...

  19. ACOPLAMIENTO MOLECULAR, 3DQSAR Y DISEÑO DE NOVO DE BENZIMIDAZOLES E IMIDAZOLINAS DERIVADOS DE (S-ISOTIAZOLIDINONAS COMO INHIBIDORES DE LA PROTEÍNA PTP 1B MOLECULAR DOCKING, 3D-QSAR AND DE NOVO DESIGN OF BENZIMIDAZOLES AND IMIDAZOLINES (S-ISOTHIAZOLIDINONES DERIVATIVES AS PTP 1B INHIBITORS

    Directory of Open Access Journals (Sweden)

    Judith C GRANADOS R

    2010-09-01

    Full Text Available Se realizó un estudio tridimensional cuantitativo de relación-estructura (3D-QSAR con 40 moléculas tipo benzimidazol e imidazolina derivadas de (s-isotiazolidinonas y su unión con el sitio activo de la proteína tirosina fosfatasa 1B (PTP 1B, utilizando el programa GOLD 3.0. La superposición molecular de los ligandos en la plantilla fue llevada a cabo por el método Database Alignment. El mejor modelo fue el constituido por la combinación de los campos estéricos y electrostáticos de CoMFA, los cuales arrojaron los siguientes parámetros: q² = 0,659 y r² = 0,997. Usando el módulo LeapFrog de SYBYL fue posible generar más de 10.000 moléculas nuevas, de las cuales 46 mostraron, teóricamente, un mejor valor de la actividad biológica que su precursora. Los datos obtenidos en el presente estudio podrían impulsar el diseño de nuevos y más potentes inhibidores de la PTP 1B, como agentes para el tratamiento de la diabetes.A study of the relationship-dimensional quantitative structure (3D-QSAR with 40 molecules derived from benzimidazole and imidazoline (s-isotiazolidinonas and their union with the active site of Protein Tyrosine Phosphatase 1B using the program GOLD 3.0 was carried out. The molecular supression of the ligands in the grid was performed by the Database Alignment method. The best model formed by combining the esteric field and electrostatic fields of CoMFA, yielded the following parameters: q² = 0.659 and r² = 0.997. Using LeapFrog module of Sybyl was possible to generate more than 10,000 new molecules of which 46 showed theoretically a better value of biological activity than their forerunner. The data generated by this study could promote the design of new and more potent PTP 1B inhibitors as agents for the treatment of diabetes.

  20. Density Functional Theory Study on Conformers of Benzoylcholine Chloride

    Directory of Open Access Journals (Sweden)

    Mustafa Karakaya

    2013-01-01

    Full Text Available The optimized molecular structures and vibrational frequencies and also gauge including atomic orbital (GIAO 1H and 13C NMR shift values of benzoylcholine chloride [(2-benzoyloxyethyl trimethyl ammonium chloride] have been calculated using density functional theory (B3LYP method with 6-31++G(d basis set. The comparison of the experimental and calculated infrared (IR, Raman, and nuclear magnetic resonance (NMR spectra has indicated that the experimental spectra are formed from the superposition of the spectra of two lowest energy conformers of the compound. So, it was concluded that the compound simultaneously exists in two optimized conformers in the ground state. Also the natural bond orbital (NBO analysis has supported the simultaneous exiting of two conformers in the ground state. The calculated optimized geometric parameters (bond lengths and bond angles and vibrational frequencies for both the lowest energy conformers were seen to be in a well agreement with the corresponding experimental data.

  1. Swell activated chloride channel function in human neutrophils

    Energy Technology Data Exchange (ETDEWEB)

    Salmon, Michael D. [Leukocyte and Ion Channel Research Laboratory, School of Health and Biosciences, University of East London, Stratford Campus, London E15 4LZ (United Kingdom); Ahluwalia, Jatinder, E-mail: j.ahluwalia@uel.ac.uk [Leukocyte and Ion Channel Research Laboratory, School of Health and Biosciences, University of East London, Stratford Campus, London E15 4LZ (United Kingdom)

    2009-04-17

    Non-excitable cells such as neutrophil granulocytes are the archetypal inflammatory immune cell involved in critical functions of the innate immune system. The electron current generated (I{sub e}) by the neutrophil NADPH oxidase is electrogenic and rapidly depolarises the membrane potential. For continuous function of the NADPH oxidase, I{sub e} has to be balanced to preserve electroneutrality, if not; sufficient depolarisation would prevent electrons from leaving the cell and neutrophil function would be abrogated. Subsequently, the depolarisation generated by the neutrophil NADPH oxidase I{sub e} must be counteracted by ion transport. The finding that depolarisation required counter-ions to compensate electron transport was followed by the observation that chloride channels activated by swell can counteract the NADPH oxidase membrane depolarisation. In this mini review, we discuss the research findings that revealed the essential role of swell activated chloride channels in human neutrophil function.

  2. CPP-603 Chloride Removal System Decontamination and Decommissioning

    International Nuclear Information System (INIS)

    The CPP-603 (annex) Chloride Removal System (CRS) Decontamination and Decommissioning (D ampersand D) Project is described in this report. The CRS was used for removing Chloride ions and other contaminants that were suspended in the waters of the underwater fuel storage basins in the CPP-603 Fuel Receiving and Storage Facility (FRSF) from 1975 to 1981. The Environmental Checklist and related documents, facility characterization, decision analysis', and D ampersand D plans' were prepared in 1991. Physical D ampersand D activities were begun in mid summer of 1992 and were completed by the end of November 1992. All process equipment and electrical equipment were removed from the annex following accepted asbestos and radiological contamination removal practices. The D ampersand D activities were performed in a manner such that no radiological health or safety hazard to the public or to personnel at the Idaho National Engineering Laboratory (INEL) occurred

  3. INNA for interelement correlations in rats after mercuric chloride exposure

    International Nuclear Information System (INIS)

    In an animal model study, we exposed rats to mercuric chloride through drinking water continuously for eight to ten months. A group of these rats were then taken off mercuric chloride water and fed distilled water. A control group of rats was given distilled water. Rat brain, spinal cord, and kidney were analyzed to determine Hg and nine other elements by INAA. Significant imbalances were detected among the groups. Most of the mercury (Hg) was found to be eliminated from the tissues studied within the first thirty days. Implications of the data are discussed in light of observed trace element imbalances in amyotrophic lateral sclerosis and Alzheimer's disease. (author) 25 refs.; 1 fig.; 3 tabs

  4. Evaluation of corrosion effect in reinforced concrete by chloride exposure

    Science.gov (United States)

    Loreto, G.; Di Benedetti, M.; Iovino, R.; Nanni, A.; Gonzalez, M. A.

    2011-04-01

    Durability is generally described as the ability of a material to maintain its physical and mechanical properties over time. In reinforced concrete (RC) structures, concrete is the ideal material to protect the steel reinforcement given its high alkalinity. In environments subjected to highly aggressive conditions, mostly due to the presence of chlorides, concrete may lose its protective characteristics and allow for accelerated ageing. Concrete degradation and steel reinforcement corrosion are phenomena closely connected. The aim of this research work is the characterization of the relationship between steel reinforcement corrosion and concrete degradation under accelerated ageing in a 3% sodium chloride solution. The method of linear polarization is used for identification of the corrosion rate of the steel bar. Additionally, the values of concrete residual strength are obtained, and correlated to both the corrosion rate and width of concrete cracks. Finally, the prediction of the concrete cover useful life is estimated.

  5. Prediction of chloride ingress and binding in cement paste

    DEFF Research Database (Denmark)

    Geiker, Mette Rica; Nielsen, Erik Pram; Herforth, Duncan

    2007-01-01

    Portland cement pastes at any content of chloride, alkalis, sulfates and carbonate was verified experimentally and found to be equally valid when applied to other data in the literature. The thermodynamic model for predicting the phase equilibria in hydrated Portland cement was introduced into an existing...... Finite Difference Model for the ingress of chlorides into concrete which takes into account its multi-component nature. The “composite theory” was then used to predict the diffusivity of each ion based on the phase assemblage present in the hydrated Portland cement paste. Agreement was found between...... steady state diffusion however. It simply implies that incremental increases in the concentration of diffusing ions in the pore solution will rapidly re-equilibrate with the hydrates present locally, where, the greater the ratio of bound to free ions, the greater the buffering effect which slows down the...

  6. CHLORIDE ION PERMEABILITY STUDIES OF METAKAOLIN BASED HIGH PERFORMANCE CONCRETE

    Directory of Open Access Journals (Sweden)

    Dr.Vaishali. G.Ghorpade,

    2011-02-01

    Full Text Available To increase the applications of HPC in India, greater under standing of HPC produced with locally available materials and indigenously produced mineral admixtures is essential. In the present investigation, HPC has been produced with locally available aggregates and metakaolin as the mineral admixture. Various metakaolin based HPC mixes were attained by absolute volume method. Cubes of 150X150X150 mm size were cast and cured for 28 days and then tested for compressive strength. Chloride ion permeability test as per ASTM C 1202 has been conducted on various HPC mixes to measure the permeability values of HPC produced with metakaolin. The experimental results indicate that metakaolin has the ability to considerably reduce the permeability of high performance concrete. The various details about the chloride ion permeability test have been presented in this paper.

  7. Sodium chloride's effect on self-assembly of diphenylalanine bilayer.

    Science.gov (United States)

    Kwon, Junpyo; Lee, Myeongsang; Na, Sungsoo

    2016-07-15

    Understanding self-assembling peptides becomes essential in nanotechnology, thereby providing a bottom-up method for fabrication of nanostructures. Diphenylalanine constitutes an outstanding building block that can be assembled into various nanostructures, including two-dimensional bilayers or nanotubes, exhibiting superb mechanical properties. It is known that the effect of the ions is critical in conformational and chemical interactions of bilayers or membranes. In this study, we analyzed the effect of sodium chloride on diphenylalanine bilayer using coarse-grained molecular dynamics simulations, and calculated the bending Young's modulus and the torsional modulus by applying normal modal analysis using an elastic network model. The results showed that sodium chloride dramatically increases the assembling efficiency and stability, thereby promising to allow the precise design and control of the fabrication process and properties of bio-inspired materials. © 2016 Wiley Periodicals, Inc. PMID:27241039

  8. Inhibition of intestinal chloride secretion by proanthocyanidins from Guazuma ulmifolia.

    Science.gov (United States)

    Hör, M; Rimpler, H; Heinrich, M

    1995-06-01

    The antisecretory activity of Guazuma ulmifolia bark was examined in rabbit distal colon mounted in an Ussing chamber. Chloride secretion was stimulated by cholera toxin and prostaglandin E2 (PGE2). Guazuma ulmifolia extract (GUE) completely inhibited cholera toxin-induced secretion if the extract was added to the mucosal bath prior to the toxin. Adding the extract after administration of the toxin had no effect on secretion. GUE did not inhibit PGE2-induced chloride secretion. These results indicate an indirect antisecretory mechanism. SDS-PAGE analysis of cholera toxin treated with GUE confirmed this presumption. GUE specifically interacted with the A subunit of the toxin. Preliminary phytochemical examinations showed that the most active fraction contains procyanidins with a degree of polymerisation higher than 8. PMID:7617760

  9. Electrochemical synthesis and characterization of chloride doped polyaniline

    Indian Academy of Sciences (India)

    A M Pharhad Hussain; A Kumar

    2003-04-01

    Chloride doped polyaniline conducting polymer films have been prepared in a protic acid medium (HCl) by potentiodynamic method in an electrochemical cell and studied by cyclic voltammetry and FTIR techniques. The FTIR spectra confirmed Cl– ion doping in the polymers. The polymerization rate was found to increase with increasing concentration of aniline monomer. But the films obtained at high monomer concentration were rough having a nonuniform flaky polyaniline distribution. Results showed that the polymerization rate did not increase beyond a critical HCl concentration. Cyclic voltammetry suggested that, the oxidation-reduction current increased with an increase in scan rate and that the undoped polyaniline films were not hygroscopic whereas chloride doped polyaniline films were found to be highly hygroscopic.

  10. Electrowinning of lead powder from chloride leach liquor

    Energy Technology Data Exchange (ETDEWEB)

    Owais, Ashour [Suez Canal Univ., Suez (Egypt). Metallurgical and Materials Engineering Dept.

    2012-11-15

    Electrowinning of lead powder from chloride leach liquor obtained from secondary lead slag leached in hydrochloric acid is the main aim of this work. The resulted lead chloride solution (leachate) containing 2.2 wt.-% Pb and 1.24 wt.-% HCl was electrowon in an electrolytic cell containing one graphite plate as inert anode and two lead sheets as starting permanent cathodes. Different electrolysis parameters such as current density, electrolyte temperature and electrolyte stirring rate were studied. As indicated by SEM, EDX and XRD analyses, fine and pure (100 % Pb) powders with a dispersed and needle-like shape were formed with cathodic current efficiency up to 67.9 % and electrical energy demand ranges from 0.809 to 4.998 kWh/kg Pb with productivity up to 2.63 g/Ah. (orig.)

  11. Does Infrared Multiphoton Dissociation of Vinyl Chloride Yield Cold Vinylidene?

    Science.gov (United States)

    Fernando, Ravin; Qu, Chen; Bowman, Joel M; Field, Robert W; Suits, Arthur G

    2015-07-01

    Velocity map imaging of the infrared multiphoton dissociation of vinyl chloride shows the formation of HCl in rotational levels below J = 10 that are associated with the three-center elimination pathway. The total translational energy release is observed to peak at 3-5 kcal/mol, which is consistent with the low reverse barrier predicted for the formation of HCl with vinylidene coproducts. Direct dynamics trajectory studies from the three-center transition state reproduce the observed distributions and show that the associated vinylidene is formed with only modest rotational excitation, precluding Coriolis-induced mixing among the excited vibrational levels of acetylene that would lead to distribution of vinylidene character into many vibrationally mixed acetylene vibrational levels. The results suggest that infrared multiphoton dissociation of vinyl chloride is an efficient route to synthesis of stable, cold vinylidene. PMID:26266719

  12. Enthalpy and entropy interaction parameters of sodium chloride with some monosaccharides in water

    Institute of Scientific and Technical Information of China (English)

    ZHUO; Kelei; WANG; Jianji; BAI; Guangyue; YAN; Haike; WANG

    2004-01-01

    Dilution enthalpies of sodium chloride and some monosaccharides (glucose, galactose, xylose, arabinose, and fructose) in water and mixing enthalpies of aqueous sodium chloride and these monosaccharide solutions were measured by using an improved precision semimicro-titration calorimeter. Transfer enthalpies of sodium chloride from water to aqueous saccharide solutions were evaluated as well as enthalpy interaction parameters of sodium chloride with these monosaccharides in water. Combined with Gibbs energy interaction parameters, entropy interaction parameters were also obtained. The results show that interactions of the saccharides with sodium chloride depend on the stereochemistry of saccharide molecules. These interaction parameters can identify stereochemical structure of saccharide molecules.

  13. Relationship between chloride diffusivity and pore structure of hardened cement paste

    Institute of Scientific and Technical Information of China (English)

    Guo-wen SUN; Wei SUN; Yun-sheng ZHANG; Zhi-yong LIU

    2011-01-01

    Based on effective media theory, a predictive model, relating chloride diffusivity to the capillary pores, gel pores,tortuosity factor, and pore size distribution of hardened cement, is proposed. To verify the proposed model, the diffusion coefficient of chloride ions, the degree of hydration, and peak radius of capillary pores of cement paste specimens were measured. The predicted results for chloride diffusivity were compared with published data. The results showed that the predicted chloride diffusivity of hardened cement paste was in good agreement with the experimental results. The effect of the evolution of pore structures in cement paste on chloride diffusivity could be deduced simultaneously using the proposed model.

  14. An insight into the passivation of cupronickel alloys in chloride environment

    Indian Academy of Sciences (India)

    J Mathiyarasu; N Palaniswamy; V S Muralidharan

    2001-02-01

    Cupronickels offer enhanced corrosion protection in marine environments by the formation of passive films on the surface. Cyclic voltammetric studies were carried on cupronickels in chloride solutions at H 6.3 to understand the role of chloride ions in passive film formation. Increase in nickel content of the alloy and of chloride ions in solution decreases film resistance. Chloride ions take part in reduction of the passive film to copper. A solid-state model for passive film formation involving chloride ions has been attempted.

  15. Processes of lithium chlorides purification from Salar de Atacama concentrated brines

    International Nuclear Information System (INIS)

    The results of research carried out to obtain lithium chloride, as a suitable electrolyte for the production of high purity lithium metal are presented. Concentrated lithium chloride brines from Salar de Atacama have been used as starting materials. The studied process requires the reduction of the boron content in the brines to levels below 5 ppm, followed by a crystallization process to obtain a crystallized lithium chloride. The elimination of the magnesium chloride co-crystallized with the lithium chloride, is achieved by a complementary washing step and the lixiviation of the impure LiCl crystals with ethanol. (author)

  16. Antidepressants and seizure-interactions at the GABA-receptor chloride-ionophore complex

    International Nuclear Information System (INIS)

    Convulsive seizures are a potential side effect of antidepressant drug treatment and can be produced by all classes of antidepressants. It is also know that some convulsant and anticonvulsant drug actions are mediated by the GABA-receptor chloride-ionophore complex. Drugs acting at this complex appear to induce convulsions by inhibiting chloride conductance through the associated chloride channel. Using the method of GABA-stimulated 36Cl-uptake by rat cerebral cortical vesicles, we show that some antidepressant drugs can inhibit the GABA-receptor chloride uptake, and that the degree of chloride channel inhibition by these drugs correlates with the frequency of convulsive seizures induced by them

  17. Chloride ingress in cement paste and mortar measured by Electron Probe Micro Analysis

    DEFF Research Database (Denmark)

    Jensen, Ole Mejlhede

    1998-01-01

    Chloride ingress is a common cause of deterioration of reinforced concrete structures. Concrete may be exposed to chloride by sea water or deicing salts. The chloride initiates corrosion of the reinforcement which through expansion disrupts the concrete. Modelling the chloride ingress is an.......Chloride ingress in modern concretes cannot be followed with conventional measuring techniques. This makes it difficult to develop and test new models. However, prefatory experiments have shown that electron probe micro analysis, EPMA, is applicable for this purpose. The geometric resolution for the EPMA method is...

  18. Structural and mechanistic studies of chloride induced activation of human pancreatic α-amylase

    OpenAIRE

    Maurus, Robert; Begum, Anjuman; Kuo, Hsin-Hen; Racaza, Andrew; Numao, Shin; Andersen, Carsten; Tams, Jeppe W.; Vind, Jesper; Overall, Christopher M.; Withers, Stephen G.; Brayer, Gary D

    2005-01-01

    The mechanism of allosteric activation of α-amylase by chloride has been studied through structural and kinetic experiments focusing on the chloride-dependent N298S variant of human pancreatic α-amylase (HPA) and a chloride-independent TAKA-amylase. Kinetic analysis of the HPA variant clearly demonstrates the pronounced activating effect of chloride ion binding on reaction rates and its effect on the pH-dependence of catalysis. Structural alterations observed in the N298S variant upon chlorid...

  19. Studies of Degradation of Plasticized Polyvinyl Chloride (PPVC)

    OpenAIRE

    Doina Elena Gavrilă

    2016-01-01

    Commercial plasticizers are introduced in Polyvinyl Chloride (PVC) to obtain flexibility, high elongation to break, durability, resistance to heat and chemicals. Very used plasticizers are phthalates, most commonly phthalate being di-2-ethyl hexyl phthalate (DEHP). The phthalates are not chemically bound to PVC and can migrate from different devices and objects due to the influence of temperature, or to other types of degradation. In article are presented the harm effects of phtha...

  20. Melt supercooling and growth of lead chloride single crystals

    Czech Academy of Sciences Publication Activity Database

    Nitsch, Karel; Cihlář, Antonín; Rodová, Miroslava

    Bratislava: NOI, 2003 - (Koman, M.; Miklos, D.), s. 49-50 ISBN 80-89088-16-3. [Joint Seminar DMS -RE 2003 /13./. Račkova dolina (SK), 15.09.2003-19.09.2003] R&D Projects: GA ČR GA202/03/0428 Institutional research plan: CEZ:AV0Z1010914 Keywords : crystal growth * lead chloride * Bridgman method * length of supercool region Subject RIV: BM - Solid Matter Physics ; Magnetism

  1. Bis[1,2-bis(dimethylphosphinoethane]dichloridonitrosyltungsten(0 chloride

    Directory of Open Access Journals (Sweden)

    Nataša Avramović

    2008-01-01

    Full Text Available In the crystal structure of the title compound, [WCl2(NO(C6H16P22]Cl, the seven-coordinated tungsten(II center displays a distorted pentagonal–bipyramidal geometry with trans nitrosyl and chloride ligands. The NO and Cl ligands are disordered over two positions; the site occupancy factors are 0.6 and 0.4.

  2. Influence of sodium chloride on wine yeast fermentation performance

    OpenAIRE

    Logothetis, Stelios

    2010-01-01

    Stilianos Logothetis1, Elias T Nerantzis2, Anna Gioulioti3, Tasos Kanelis2, Tataridis Panagiotis2, Graeme Walker11University of Abertay Dundee, School of Contemporary Sciences, Dundee, Scotland; 2TEI of Athens Department of Oenology and Spirit Technology, Biotechnology and Industrial Fermentations Lab Agiou Spiridonos, Athens, Greece; 3Ampeloiniki SA Industrial Park Thermi, Thessaloniki, GreeceAbstract: This paper concerns research into the influence of salt (sodium chloride) on growth, viabi...

  3. Sequential injection titration of chloride in milk with potentiometric detection

    OpenAIRE

    Lima, M.J. Reis; Fernandes, Sílvia M. V.; Rangel, António O.S.S.

    2004-01-01

    In this work, a sequential injection system for the pseudo-titration of chloride in milk is described. Milk was directly aspirated into the system and sandwiched between two silver nitrate plugs (titrant). The aspirated zones were then propelled to the detector (Ag2S/Ag tubular electrode), where the depletion in the titrant silver concentration (due to the formation of a AgCl precipitate) was monitored. The results obtained by the developed sequential injection titration method were ...

  4. Thionyl-chloride-induced lung injury and bronchiolitis obliterans

    Energy Technology Data Exchange (ETDEWEB)

    Konichezky, S.; Schattner, A.; Ezri, T.; Bokenboim, P.; Geva, D. (Kaplan Hospital, Rehovot (Israel))

    1993-09-01

    Thionyl-chloride (TCl) is used in the manufacture of lithium batteries, producing SO2 and HCl fumes on contact with water. We report two cases of accidental TCl exposure resulting in lung injury that may vary from a relatively mild and reversible interstitial lung disease to a severe form of bronchiolitis obliterans causing, after a latent period, an acute/chronic respiratory failure as well as other complications (spontaneous pneumothorax and bronchopleural fistula), previously unreported in TCl fume inhalation.

  5. Polarization and charge transfer in the hydration of chloride ions

    International Nuclear Information System (INIS)

    A theoretical study of the structural and electronic properties of the chloride ion and water molecules in the first hydration shell is presented. The calculations are performed on an ensemble of configurations obtained from molecular dynamics simulations of a single chloride ion in bulk water. The simulations utilize the polarizable AMOEBA force field for trajectory generation and MP2-level calculations are performed to examine the electronic structure properties of the ions and surrounding waters in the external field of more distant waters. The ChelpG method is employed to explore the effective charges and dipoles on the chloride ions and first-shell waters. The quantum theory of atoms in molecules (QTAIM) is further utilized to examine charge transfer from the anion to surrounding water molecules. The clusters extracted from the AMOEBA simulations exhibit high probabilities of anisotropic solvation for chloride ions in bulk water. From the QTAIM analysis, 0.2 elementary charges are transferred from the ion to the first-shell water molecules. The default AMOEBA model overestimates the average dipole moment magnitude of the ion compared to the quantum mechanical value. The average magnitude of the dipole moment of the water molecules in the first shell treated at the MP2-level, with the more distant waters handled with an AMOEBA effective charge model, is 2.67 D. This value is close to the AMOEBA result for first-shell waters (2.72 D) and is slightly reduced from the bulk AMOEBA value (2.78 D). The magnitude of the dipole moment of the water molecules in the first solvation shell is most strongly affected by the local water-water interactions and hydrogen bonds with the second solvation shell, rather than by interactions with the ion.

  6. Polarization and charge transfer in the hydration of chloride ions

    Science.gov (United States)

    Zhao, Zhen; Rogers, David M.; Beck, Thomas L.

    2010-01-01

    A theoretical study of the structural and electronic properties of the chloride ion and water molecules in the first hydration shell is presented. The calculations are performed on an ensemble of configurations obtained from molecular dynamics simulations of a single chloride ion in bulk water. The simulations utilize the polarizable AMOEBA force field for trajectory generation and MP2-level calculations are performed to examine the electronic structure properties of the ions and surrounding waters in the external field of more distant waters. The ChelpG method is employed to explore the effective charges and dipoles on the chloride ions and first-shell waters. The quantum theory of atoms in molecules (QTAIM) is further utilized to examine charge transfer from the anion to surrounding water molecules. The clusters extracted from the AMOEBA simulations exhibit high probabilities of anisotropic solvation for chloride ions in bulk water. From the QTAIM analysis, 0.2 elementary charges are transferred from the ion to the first-shell water molecules. The default AMOEBA model overestimates the average dipole moment magnitude of the ion compared to the quantum mechanical value. The average magnitude of the dipole moment of the water molecules in the first shell treated at the MP2-level, with the more distant waters handled with an AMOEBA effective charge model, is 2.67 D. This value is close to the AMOEBA result for first-shell waters (2.72 D) and is slightly reduced from the bulk AMOEBA value (2.78 D). The magnitude of the dipole moment of the water molecules in the first solvation shell is most strongly affected by the local water-water interactions and hydrogen bonds with the second solvation shell, rather than by interactions with the ion.

  7. Chloride transport through cementitious membranes using pulsed current

    OpenAIRE

    Diaz, B.; Novoa, X.Ramon; Puga, Beatriz; Vivier, Vincent

    2013-01-01

    International audience Microstructural changes and chloride transport in cement pastes are studied under DC current and pulsed electric fields. Impedance spectroscopy and ultrasonic pulse velocity measurements have been employed for quasi-real time monitoring of changes in the cement paste microstructure. The results show that the electric resistivity and ultrasound velocity (measured at 500 kHz) are modified during the migration experiments. At the end of test, mercury intrusion porosimet...

  8. Hibiscus sabdariffa Affects Ammonium Chloride-Induced Hyperammonemic Rats

    OpenAIRE

    Subramanian, P.; M. Mohamed Essa

    2007-01-01

    Hibiscus sabdariffa (HS) is an edible medicinal plant, indigenous to India, China and Thailand and is used in Ayurveda and traditional medicine. Alcoholic extract of HS leaves (HSEt) was studied for its anti-hyperammonemic and antioxidant effects in brain tissues of ammonium chloride-induced hyperammonemic rats. Oral administration of HSEt (250 mg kg−1 body weight) significantly normalizes the levels of ammonia, urea, uric acid, creatinine and non-protein nitrogen in the blood. HSEt significa...

  9. Intergranular Corrosion of 2024 Alloy in Chloride Solutions

    OpenAIRE

    Augustin, Christel; Andrieu, Eric; Blanc, Christine; Mankowski, Georges; Delfosse, Jérôme

    2007-01-01

    Experiments were performed to determine the propagation kinetics of intergranular corrosion on 2024 aluminum alloy immersed in 1 and 3 M chloride solutions. Tests consisting of immersion in a corrosive solution followed by optical observations on sectioned samples were carried out. This method was found to be time consuming and led to a lack of reproducibility due to the random nature of the corrosion attacks. Another method proved to be more efficient; it consisted of measuring the load to f...

  10. A spontaneous, tonic chloride conductance in solitary glutamatergic hippocampal neurons

    OpenAIRE

    Eisenman, Lawrence N.; Kress, Geraldine; Charles F. Zorumski; Mennerick, Steven

    2006-01-01

    GABA-A receptors mediate both phasic synaptic inhibition and more recently appreciated tonic currents in the vertebrate central nervous system. We addressed discrepancies in the literature regarding the pharmacology of tonic currents by examining tonic currents in a controlled environment of dissociated, solitary glutamatergic neurons. We describe a novel tonically active, bicuculline-sensitive chloride conductance that is insensitive to gabazine and to picrotoxin and thus not mediated by con...

  11. Binary Nucleation in Aqueous Electrolyte Systems. Sodium Chloride

    Czech Academy of Sciences Publication Activity Database

    Němec, Tomáš; Maršík, František

    Gdansk: IFFM Publishers, 2005 - (Mikielewicz, J.; Butrymowicz, D.; Trela, M.; Cieslinski, J.), s. 395-400 ISBN 83-88237-90-X. [HEAT 2005 : International Conference on Transport Phenomena in Multiphase Systems. Gdansk (PL), 26.06.2005-30.06.2005] R&D Projects: GA ČR(CZ) GA101/05/2536 Institutional research plan: CEZ:AV0Z20760514 Keywords : binary nucleation * sodium chloride * water Subject RIV: BJ - Thermodynamics

  12. Synthesis and thermal behavior of polyacrylonitrile/vinylidene chloride copolymer

    OpenAIRE

    Robson Fleming; Luiz Claudio Pardini; Nilton Alves; Elson Garcia; Carlos Brito Júnior

    2014-01-01

    Polyacrylonitrile fiber encompasses a broad range of products based on acrylonitrile (AN) which is readily copolymerized with a wide range of ethylenic unsaturated monomers giving rise to polymers with different characteristics and applications. Such products can be designed for cost-effective, flame and heat resistant solutions for the textile industry, aircraft and automotive markets. In the present work acrylonitrile was copolymerized with vinylidene chloride (VDC) by conventional suspensi...

  13. Modeling acid-gas generation from boiling chloride brines

    OpenAIRE

    Sonnenthal Eric; Spycher Nicolas; Zhang Guoxiang; Steefel Carl

    2009-01-01

    Abstract Background This study investigates the generation of HCl and other acid gases from boiling calcium chloride dominated waters at atmospheric pressure, primarily using numerical modeling. The main focus of this investigation relates to the long-term geologic disposal of nuclear waste at Yucca Mountain, Nevada, where pore waters around waste-emplacement tunnels are expected to undergo boiling and evaporative concentration as a result of the heat released by spent nuclear fuel. Processes...

  14. Synthesis and catalytic activity of tetraphenylporphyrinate chloride of uranium (4)

    International Nuclear Information System (INIS)

    A new complex, uranium (4), tetraphenyl porphyrinate chloride, that is an active catalyst of cholesterine oxidation is synthesized by tetraphenyl porphyrine interaction with UCl4 solution in pyridine, the yield being 20%. The composition melting point is above 400 deg, Rf 0.5 (silufol; chloroform-ethanol 1:1), UV spectrum in benzene (λmax, nm(εx103)):425(180), 540(8)

  15. Hematologic depression following therapy with strontium-89 chloride

    International Nuclear Information System (INIS)

    Initial clinical trials using strontium-89 (Sr-89) chloride for the treatment of painful skeletal metastases have observed minimal or no hematological depression secondary to the radiostrontium. A patient with marked bone marrow depression temporally related to the administration of the Sr-89 is reported, and the need for close hematological monitoring is emphasized. Bone marrow tumor replacement may predispose patients to marrow depression from radiostrontium, and such patients should be treated with caution

  16. Benzalkonium Chloride Induced Bronchoconstriction in Patients with Stable Bronchial Asthma

    OpenAIRE

    Lee, Byoung Hoon; Kim, Sang-Hoon

    2007-01-01

    Background Although benzalkonium chloride (BAC)-induced bronchoconstriction occurs in patients with bronchial asthma, BAC-containing nebulizer solutions are still being used in daily practice in Korea. The aim of this study was to evaluate the effects of inhaled aqueous solutions containing BAC. Methods Thirty subjects with bronchial asthma and 10 normal controls inhaled up to three 600 µg nebulized doses of BAC using a jet nebulizer. FEV1 (forced expiratory volume at one second) was measured...

  17. Discoloration of Synthetic Dyeing Wastewater Using Polyaluminium Chloride

    OpenAIRE

    Bogoeva-Gaceva, Gordana; BUŽAROVSKA, Aleksandra; DIMZOSKI, Bojan

    2010-01-01

    The efficiency of polyaluminium chloride (PAC) in discoloration of synthetic dyeing wastewater composed of reactive or direct dye has been investigated, taking into account the proven advantages of PAC in water purification processes (compared to the conventional coagulants such as Al2(SO4)3, FeSO4, etc.). The efficiency of PAC was determined by UV/VIS spectroscopy, controlling the UV/VIS absorbance changes of the wastewater samples after their treatment with the appropriate amount of PAC. Co...

  18. Preparation of polymeric aluminium ferric chloride from bauxite tailings

    OpenAIRE

    Ma D; Guo M; Zhang M

    2013-01-01

    Bauxite tailings are the main solid wastes in the ore dressing process. The Al2O3 and Fe2O3 contents in bauxite tailings can reach 50% and 13% respectively. The present study proposed a feasible method to use bauxite tailings to prepare polymeric aluminium ferric chloride (PAFC), a new composite inorganic polymer for water purification. Bauxite tailings roasted reacting with hydrochloric acid under air, pickle liquor which mainly contains Fe3+, Al3+ was generated, then calcium aluminate...

  19. Comment on "Local impermeant anions establish the neuronal chloride concentration".

    Science.gov (United States)

    Luhmann, Heiko J; Kirischuk, Sergei; Kilb, Werner

    2014-09-01

    Glykys et al. (Reports, 7 February 2014, p. 670) proposed that cytoplasmic impermeant anions and polyanionic extracellular matrix glycoproteins establish the local neuronal intracellular chloride concentration, [Cl(-)]i, and thereby the polarity of γ-aminobutyric acid type A (GABAA) receptor signaling. The experimental procedures and results in this study are insufficient to support these conclusions. Contradictory results previously published by these authors and other laboratories are not referred to. PMID:25190788

  20. PCDD/F catalysis by metal chlorides and oxides.

    Science.gov (United States)

    Zhang, Mengmei; Yang, Jie; Buekens, Alfons; Olie, Kees; Li, Xiaodong

    2016-09-01

    Model fly ash (MFA) samples were composed of silica, sodium chloride, and activated carbon, and doped with metal (0.1 wt% Cu, Cr, Ni, Zn and Cd) chloride or oxide. Each sample was de novo tested at 350 °C for 1 h, in a flow of gas (N2, N2 + 10% O2, +21% O2 or +10% H2) to investigate the effect of metal catalyst and gas composition on PCDD/F formation. Total PCDD/F yield rises rapidly with oxygen content, while the addition of hydrogen inhibits the formation and chlorination of PCDD/F. The amount of PCDD on average rises linearly with the oxygen concentration, while that of PCDF follows a reaction order of about 1/2; thus the PCDF to PCDD ratio drops when more oxygen becomes available. Some samples do not follow this trend. Chlorides are much more active than oxides, yet there are marked differences between individual metals. Principal component analysis (PCA) was applied to study the signatures from all samples, showing their unique specificity and diversity. Each catalyst shows a different signature within its individual homologue groups, demonstrating that these signatures are not thermodynamically controlled. Average congener patterns do not vary considerably with oxygen content changing from oxidising (air) to reducing (nitrogen, hydrogen). PMID:27341157