WorldWideScience

Sample records for chipping headrig

  1. Chip, Chip, Hooray!

    Science.gov (United States)

    Kelly, Susan

    2001-01-01

    Presents a science laboratory using different brands of potato chips in which students test their oiliness, size, thickness, saltiness, quality, and cost, then analyze the results to determine the best chip. Gives a brief history of potato chips. (YDS)

  2. Atom chips

    CERN Document Server

    Reichel, Jakob

    2010-01-01

    This book provides a stimulating and multifaceted picture of a rapidly developing field. The first part reviews fundamentals of atom chip research in tutorial style, while subsequent parts focus on the topics of atom-surface interaction, coherence on atom chips, and possible future directions of atom chip research. The articles are written by leading researchers in the field in their characteristic and individual styles.

  3. Chips 2020

    CERN Document Server

    2016-01-01

    The release of this second volume of CHIPS 2020 coincides with the 50th anniversary of Moore’s Law, a critical year marked by the end of the nanometer roadmap and by a significantly reduced annual rise in chip performance. At the same time, we are witnessing a data explosion in the Internet, which is consuming 40% more electrical power every year, leading to fears of a major blackout of the Internet by 2020. The messages of the first CHIPS 2020, published in 2012, concerned the realization of quantum steps for improving the energy efficiency of all chip functions. With this second volume, we review these messages and amplify upon the most promising directions: ultra-low-voltage electronics, nanoscale monolithic 3D integration, relevant-data, brain- and human-vision-inspired processing, and energy harvesting for chip autonomy. The team of authors, enlarged by more world leaders in low-power, monolithic 3D, video, and Silicon brains, presents new vistas in nanoelectronics, promising  Moore-like exponential g...

  4. Atom Chips

    CERN Document Server

    Folman, R; Cassettari, D; Hessmo, B; Maier, T; Schmiedmayer, J; Folman, Ron; Krüger, Peter; Cassettari, Donatella; Hessmo, Björn; Maier, Thomas

    1999-01-01

    Atoms can be trapped and guided using nano-fabricated wires on surfaces, achieving the scales required by quantum information proposals. These Atom Chips form the basis for robust and widespread applications of cold atoms ranging from atom optics to fundamental questions in mesoscopic physics, and possibly quantum information systems.

  5. Pixel detector readout chip

    CERN Multimedia

    1991-01-01

    Close-up of a pixel detector readout chip. The photograph shows an aera of 1 mm x 2 mm containing 12 separate readout channels. The entire chip contains 1000 readout channels (around 80 000 transistors) covering a sensitive area of 8 mm x 5 mm. The chip has been mounted on a silicon detector to detect high energy particles.

  6. Chip Multithreaded Consistency Model

    Institute of Scientific and Technical Information of China (English)

    Zu-Song Li; Dan-Dan Huan; Wei-Wu Hu; Zhi-Min Tang

    2008-01-01

    Multithreaded technique is the developing trend of high performance processor. Memory consistency model is essential to the correctness, performance and complexity of multithreaded processor. The chip multithreaded consistency model adapting to multithreaded processor is proposed in this paper. The restriction imposed on memory event ordering by chip multithreaded consistency is presented and formalized. With the idea of critical cycle built by Wei-Wu Hu, we prove that the proposed chip multithreaded consistency model satisfies the criterion of correct execution of sequential consistency model. Chip multithreaded consistency model provides a way of achieving high performance compared with sequential consistency model and ensures the compatibility of software that the execution result in multithreaded processor is the same as the execution result in uniprocessor. The implementation strategy of chip multithreaded consistency model in Godson-2 SMT processor is also proposed. Godson-2 SMT processor supports chip multithreaded consistency model correctly by exception scheme based on the sequential memory access queue of each thread.

  7. Causes of stem end chip defect in chipping potatoes

    Science.gov (United States)

    Stem-end chip defect (SECD) is a serious tuber quality concern that affects chipping potatoes. This defect is characterized by dark-colored vascular tissues and adjacent cortical tissues at the tuber stem-end of potato chips after frying. Chips with SECD are unappealing to consumers and raw product ...

  8. ALICE chip processor

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    This tiny chip provides data processing for the time projection chamber on ALICE. Known as the ALICE TPC Read Out (ALTRO), this device was designed to minimize the size and power consumption of the TPC front end electronics. This single chip contains 16 low-power analogue-to-digital converters with six million transistors of digital processing and 8 kbits of data storage.

  9. CHIP, CHIP, ARRAY! THREE CHIPS FOR POST-GENOMIC RESEARCH

    Science.gov (United States)

    Cambridge Healthtech Institute recently held the 4th installment of their popular "Lab-on-a-Chip" series in Zurich, Switzerland. As usual, it was enthusiastically received and over 225 people attended the 2-1/2 day meeting to see and hear about some of the latest developments an...

  10. Advanced flip chip packaging

    CERN Document Server

    Lai, Yi-Shao; Wong, CP

    2013-01-01

    Advanced Flip Chip Packaging presents past, present and future advances and trends in areas such as substrate technology, material development, and assembly processes. Flip chip packaging is now in widespread use in computing, communications, consumer and automotive electronics, and the demand for flip chip technology is continuing to grow in order to meet the need for products that offer better performance, are smaller, and are environmentally sustainable. This book also: Offers broad-ranging chapters with a focus on IC-package-system integration Provides viewpoints from leading industry executives and experts Details state-of-the-art achievements in process technologies and scientific research Presents a clear development history and touches on trends in the industry while also discussing up-to-date technology information Advanced Flip Chip Packaging is an ideal book for engineers, researchers, and graduate students interested in the field of flip chip packaging.

  11. China's first WLAN chips

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ The wireless local area network (WLAN) chips independently developed by CAS researchers were in the limelight of the recent Electronic Manufacture Exposition held in Suzhou, east China's Jiangsu Province.

  12. CHIP Enrollment Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — CHIP quarterly and annual statistical enrollment reports. The quarterly reports contain point-in-time and ever enrolled data and the annual reports contain ever...

  13. Medicaid CHIP ESPC Database

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Environmental Scanning and Program Characteristic (ESPC) Database is in a Microsoft (MS) Access format and contains Medicaid and CHIP data, for the 50 states...

  14. SU-8 cantilever chip interconnection

    DEFF Research Database (Denmark)

    Johansson, Alicia Charlotte; Janting, Jakob; Schultz, Peter;

    2006-01-01

    the electrodes on the SU-8 chip to a printed circuit board. Here, we present two different methods of electrically connecting an SU-8 chip, which contains a microfluidic network and free-hanging mechanical parts. The tested electrical interconnection techniques are flip chip bonding using underfill or flip chip...... bonding using an anisotropic conductive film (ACF). These are both widely used in the Si industry and might also be used for the large scale interconnection of SU-8 chips. The SU-8 chip, to which the interconnections are made, has a microfluidic channel with integrated micrometer-sized cantilevers...... that can be used for label-free biochemical detection. All the bonding tests are compared with results obtained using similar Si chips. It is found that it is significantly more complicated to interconnect SU-8 than Si cantilever chips primarily due to the softness of SU-8....

  15. Fuzzy Logic Control ASIC Chip

    Institute of Scientific and Technical Information of China (English)

    沈理

    1997-01-01

    A fuzzy logic control VLSI chip,F100,for industry process real-time control has been designed and fabricated with 0.8μm CMOS technology.The chip has the features of simplicity,felexibility and generality.This paper presents the Fuzzy control inrerence method of the chip,its VLSI implementation,and testing esign consideration.

  16. World with Chips

    Science.gov (United States)

    Hoefflinger, Bernd

    Although we are well advised to look at the future 1 day at a time, we have seen in the chapters of this book, and they necessarily could cover only a selection on the features and applications of those tiny chips, that their potential continues to grow at the exceptional rates of the past. However, the new commitment has to be towards Sustainable Nanoelectronics, guided by creating sensing, computing, memory, and communication functions, which move just a few electrons per operation, each operation consuming energy less than one or a few femtojoule, less than any of the 1014 synapses in our brains. At these energy levels, chips can serve everywhere, making them ubiquitous, pervasive, certainly wireless, and often energy-autonomous. The expected six Billion users of these chips in 2020, through their mobile, intelligent companions, will benefit from global and largely equal access to information, education, knowledge, skills, and care.

  17. Trapping molecules on chips

    CERN Document Server

    Santambrogio, Gabriele

    2015-01-01

    In the last years, it was demonstrated that neutral molecules can be loaded on a microchip directly from a supersonic beam. The molecules are confined in microscopic traps that can be moved smoothly over the surface of the chip. Once the molecules are trapped, they can be decelerated to a standstill, for instance, or pumped into selected quantum states by laser light or microwaves. Molecules are detected on the chip by time-resolved spatial imaging, which allows for the study of the distribution in the phase space of the molecular ensemble.

  18. Flock on a chip

    Science.gov (United States)

    Bartolo, Denis; Desreumaux, Nicolas

    2015-11-01

    We will show how to motorize colloidal particles capable of sensing the orientation of their neighbors and how to handle them in microfluidic chips. These populations of colloidal rollers display non-equilibrium transitions toward swarming or swirling motion depending on the system geometry . After characterizing these emergent patterns we will quantitatively describe them by means of an hydrodynamic theory of polar active liquids.

  19. Mikrofluidik-Chips

    NARCIS (Netherlands)

    Verpoorte, E.; Lichtenberg, J.

    2000-01-01

    Microfluidic chips are becoming the new paradigm for chemical processing and analysis in the laboratory. Hair-fine channels made in planar substrates using silicon processing technologies replace beakers and tubing for automated liquid transport and handling on a sub-μ L scale. Reduced conduit diame

  20. Praktijkonderzoek naar chip's

    NARCIS (Netherlands)

    Huiskes, J.H.

    1989-01-01

    Momenteel wordt door onderzoek en bedrijfsleven hard gewerkt aan de ontwikkeling van een injecteerbaar electronische transponder voor varkens. Deze transponder, in de wandeling chip genoemd bevat het levensnummer van het varken. Het levensnummer gaat het hele leven van het varken mee.

  1. Fish and chips

    OpenAIRE

    Delvenne, Philippe; Deprez, Manuel; Bisig, Bettina; JAMAR, Mauricette; Boniver, Jacques; Bours, Vincent; Herens, Christian

    2010-01-01

    Academic hospital laboratories should offer patients the possibility to have the most accurate diagnosis by the development of new analyses, such as molecular biology tests including FISH (Fluorescent In Situ Hybridization) and chips (microarrays,...). The purpose of this article is to describe the principles and the potential applications of these techniques.

  2. Preservation of forest wood chips

    Energy Technology Data Exchange (ETDEWEB)

    Kofman, P.D.; Thomsen, I.M.; Ohlsson, C.; Leer, E.; Ravn Schmidt, E.; Soerensen, M.; Knudsen, P.

    1999-01-01

    As part of the Danish Energy Research Programme on biomass utilisation for energy production (EFP), this project concerns problems connected to the handling and storing of wood chips. In this project, the possibility of preserving wood chips of the Norway Spruce (Picea Abies) is addressed, and the potential improvements by anaerobic storage are tested. Preservation of wood chips aims at reducing dry matter losses from extensive heating during storage and to reduce production of fungal spores. Fungal spores pose a health hazards to workers handling the chips. Further the producers of wood chips are interested in such a method since it would enable them to give a guarantee for the delivery of homogeneous wood chips also during the winter period. Three different types of wood chips were stored airtight and further one of these was stored in accordance with normal practise and use as reference. The results showed that airtight storage had a beneficial impact on the quality of the chips: no redistribution of moisture, low dry matter losses, unfavourable conditions for microbial activity of most fungi, and the promotion of yeasts instead of fungi with airborne spores. Likewise the firing tests showed that no combustion problems, and no increased risk to the environment or to the health of staff is caused by anaerobic storage of wood chips. In all, the tests of the anaerobic storage method of forest wood chips were a success and a large-scale test of the method will be carried out in 1999. (au)

  3. Dental Care for Medicaid and CHIP Enrollees

    Science.gov (United States)

    ... Amendments Dental Care Dental Care for Medicaid and CHIP Enrollees Dental health is an important part of ... for dental services. Dental Benefits for Children in CHIP States that provide CHIP coverage to children through ...

  4. Ultra-thin chip technology and applications

    CERN Document Server

    2010-01-01

    Ultra-thin chips are the "smart skin" of a conventional silicon chip. This book shows how very thin and flexible chips can be fabricated and used in many new applications in microelectronics, microsystems, biomedical and other fields. It provides a comprehensive reference to the fabrication technology, post processing, characterization and the applications of ultra-thin chips.

  5. Repairable chip bonding/interconnect process

    Science.gov (United States)

    Bernhardt, Anthony F.; Contolini, Robert J.; Malba, Vincent; Riddle, Robert A.

    1997-01-01

    A repairable, chip-to-board interconnect process which addresses cost and testability issues in the multi-chip modules. This process can be carried out using a chip-on-sacrificial-substrate technique, involving laser processing. This process avoids the curing/solvent evolution problems encountered in prior approaches, as well is resolving prior plating problems and the requirements for fillets. For repairable high speed chip-to-board connection, transmission lines can be formed on the sides of the chip from chip bond pads, ending in a gull wing at the bottom of the chip for subsequent solder.

  6. Chips with everything

    CERN Document Server

    CERN. Geneva

    2007-01-01

    In March 1972, Sir Robin Saxby gave a talk to the Royal Television Society called 'TV and Chips' about a 'state of the art' integrated circuit, containing 50 resistors and 50 transistors. Today's 'state of the art' chips contain up to a billion transistors. This enormous leap forward illustrates how dramatically the semiconductor industry has evolved in the past 34 years. The next 10 years are predicted to bring times of turbulent change for the industry, as more and more digital devices are used around the world. In this talk, Sir Robin will discuss the history of the Microchip Industry in parallel with ARM's history, demonstrating how a small European start-up can become a world player in the IT sector. He will also present his vision of important applications and developments in the next 20 years that are likely to become even more pervasive than the mobile phone is today, and will provide anecdotes and learning points from his own experience at ARM. About ARM: Sir Robin and a group of designers from Acorn...

  7. S-Chip Technical Assistance

    Data.gov (United States)

    U.S. Department of Health & Human Services — The page will provide access to reports and other published products designed to assist states with complicated S-Chip technical issues. The reports and products...

  8. Sampling Ocsilloscope On-Chip

    OpenAIRE

    Forsgren, Niklas

    2003-01-01

    Signal-integrity degradation from such factors as supply and substrate noise and cross talk between interconnects restricts the performance advances in Very Large Scale Integration (VLSI). To avoid this and to keep the signal-integrity, accurate measurements of the on-chip signal must be performed to get an insight in how the physical phenomenon affects the signals. High-speed digital signals can be taken off chip, through buffers that add delay. Propagating a signal through buffers restores...

  9. Whole-Teflon microfluidic chips

    OpenAIRE

    Ren, Kangning; Dai, Wen; Zhou, Jianhua; Su, Jing; Wu, Hongkai

    2011-01-01

    Although microfluidics has shown exciting potential, its broad applications are significantly limited by drawbacks of the materials used to make them. In this work, we present a convenient strategy for fabricating whole-Teflon microfluidic chips with integrated valves that show outstanding inertness to various chemicals and extreme resistance against all solvents. Compared with other microfluidic materials [e.g., poly(dimethylsiloxane) (PDMS)] the whole-Teflon chip has a few more advantages, ...

  10. Stem end chip defect in tubers used for potato chip production

    Science.gov (United States)

    Stem-end chip defect (SECD) is a serious tuber quality concern that affects chipping potatoes (Solanum tuberosum). SECD defect is characterized by dark-colored vascular tissues and adjacent cortical tissues at the tuber stem-end portion of potato chips after frying. Chips with SECD are unattractive ...

  11. Process for 3D chip stacking

    Science.gov (United States)

    Malba, Vincent

    1998-01-01

    A manufacturable process for fabricating electrical interconnects which extend from a top surface of an integrated circuit chip to a sidewall of the chip using laser pantography to pattern three dimensional interconnects. The electrical interconnects may be of an L-connect or L-shaped type. The process implements three dimensional (3D) stacking by moving the conventional bond or interface pads on a chip to the sidewall of the chip. Implementation of the process includes: 1) holding individual chips for batch processing, 2) depositing a dielectric passivation layer on the top and sidewalls of the chips, 3) opening vias in the dielectric, 4) forming the interconnects by laser pantography, and 5) removing the chips from the holding means. The process enables low cost manufacturing of chips with bond pads on the sidewalls, which enables stacking for increased performance, reduced space, and higher functional per unit volume.

  12. Development, Fabrication and Characterisation of Atom Chips

    OpenAIRE

    Groth, Sönke

    2006-01-01

    Atom chips are robust and extremely powerful toolboxes for quantum optical experiments, since they make it possible to create exceedingly precise magnetic traps for neutral atoms with minimal field modulations. Accurate manipulation of trapped atoms is feasible with magnetic and electric fields created on the atom chip. Therefore atom chips with high quality surfaces and extremely well defined wires were build (roughness < 20nm). Furthermore new generations of atom chips were developed, like ...

  13. Near Field On Chip RFID Antenna Design

    OpenAIRE

    Vargas, Alberto; Vojtech, Lukas

    2010-01-01

    The process of fabricating the antenna on the top of the RFID chip eliminates the need for a separated and costly expensive process for antenna printing and assemblage, compulsory for a separated "off-chip" antenna which is much more times larger than the chip itself. This

  14. Chip Advancer For GPS Receiver

    Science.gov (United States)

    Meehan, Thomas K.; Srinivasan, Jeffrey M.; Thomas, J. Brooks

    1989-01-01

    Instrument errors made negligible. For each integration interval, both delay and rate of change of delay initialized to small fraction of chip - for example, to order of 10 to the negative 7th power - thereby making feedback control and extraction of delay highly accurate and flexible. With appropriate selection of sampling rate relative to chip rate, commensurability errors reduced to extremely small levels. In Global Positioning System (GPS) receiver, pseudorandom code sequence generated by simple digital logic incorporating effects of time, delay, and rate of change of delay. Flexibility in starting time and sum interval very useful in aligning correlation interval with beginnings and endings of data bits.

  15. Programmable Multi-Chip Module

    Science.gov (United States)

    Kautz, David; Morgenstern, Howard; Blazek, Roy J.

    2004-11-16

    A multi-chip module comprising a low-temperature co-fired ceramic substrate having a first side on which are mounted active components and a second side on which are mounted passive components, wherein this segregation of components allows for hermetically sealing the active components with a cover while leaving accessible the passive components, and wherein the passive components are secured using a reflow soldering technique and are removable and replaceable so as to make the multi-chip module substantially programmable with regard to the passive components.

  16. Atom chip gravimeter

    Science.gov (United States)

    Schubert, Christian; Abend, Sven; Gebbe, Martina; Gersemann, Matthias; Ahlers, Holger; Müntinga, Hauke; Matthias, Jonas; Sahelgozin, Maral; Herr, Waldemar; Lämmerzahl, Claus; Ertmer, Wolfgang; Rasel, Ernst

    2016-04-01

    Atom interferometry has developed into a tool for measuring rotations [1], accelerations [2], and testing fundamental physics [3]. Gravimeters based on laser cooled atoms demonstrated residual uncertainties of few microgal [2,4] and were simplified for field applications [5]. Atomic gravimeters rely on the interference of matter waves which are coherently manipulated by laser light fields. The latter can be interpreted as rulers to which the position of the atoms is compared. At three points in time separated by a free evolution, the light fields are pulsed onto the atoms. First, a coherent superposition of two momentum states is produced, then the momentum is inverted, and finally the two trajectories are recombined. Depending on the acceleration the atoms experienced, the number of atoms detected in the output ports will change. Consequently, the acceleration can be determined from the output signal. The laser cooled atoms with microkelvin temperatures used in state-of-the-art gravimeters impose limits on the accuracy [4]. Therefore, ultra-cold atoms generated by Bose-Einstein condensation and delta-kick collimation [6,7] are expected to be the key for further improvements. These sources suffered from a low flux implying an incompatible noise floor, but a competitive performance was demonstrated recently with atom chips [8]. In the compact and robust setup constructed for operation in the drop tower [6] we demonstrated all steps necessary for an atom chip gravimeter with Bose-Einstein condensates in a ground based operation. We will discuss the principle of operation, the current performance, and the perspectives to supersede the state of the art. The authors thank the QUANTUS cooperation for contributions to the drop tower project in the earlier stages. This work is supported by the German Space Agency (DLR) with funds provided by the Federal Ministry for Economic Affairs and Energy (BMWi) due to an enactment of the German Bundestag under grant numbers DLR 50WM

  17. Programmable synaptic chip for electronic neural networks

    Science.gov (United States)

    Moopenn, A.; Langenbacher, H.; Thakoor, A. P.; Khanna, S. K.

    1988-01-01

    A binary synaptic matrix chip has been developed for electronic neural networks. The matrix chip contains a programmable 32X32 array of 'long channel' NMOSFET binary connection elements implemented in a 3-micron bulk CMOS process. Since the neurons are kept off-chip, the synaptic chip serves as a 'cascadable' building block for a multi-chip synaptic network as large as 512X512 in size. As an alternative to the programmable NMOSFET (long channel) connection elements, tailored thin film resistors are deposited, in series with FET switches, on some CMOS test chips, to obtain the weak synaptic connections. Although deposition and patterning of the resistors require additional processing steps, they promise substantial savings in silicon area. The performance of synaptic chip in a 32-neuron breadboard system in an associative memory test application is discussed.

  18. Solid state silicon based condenser microphone for hearing aid, has transducer chip and IC chip between intermediate chip and openings on both sides of intermediate chip, to allow sound towards diaphragm

    DEFF Research Database (Denmark)

    2000-01-01

    NOVELTY - A silicon transducer chip (1) has parallel backplate and movable diaphragm (12) and forms an electrical capacitor. The chip and electronic circuit chip (3) are provided on either sides of intermediate chip (2). The chip (2) has openings (4,10) between two sides of the chip, to allow sound...... towards diaphragm. Surface of the chip (2) has electrical conductors (14) to connect chip with IC chip (3). USE - For use in miniature electroacoustic devices such as hearing aid. ADVANTAGE - Since sound inlet is covered by filter, dust, moisture and other impurities do not obstruct interior and sound...

  19. Reconfigurable Networks-on-Chip

    CERN Document Server

    Chen, Sao-Jie; Tsai, Wen-Chung; Hu, Yu-Hen

    2012-01-01

    This book provides a comprehensive survey of recent progress in the design and implementation of Networks-on-Chip. It addresses a wide spectrum of on-chip communication problems, ranging from physical, network, to application layers. Specific topics that are explored in detail include packet routing, resource arbitration, error control/correction, application mapping, and communication scheduling. Additionally, a novel bi-directional communication channel NoC (BiNoC) architecture is described, with detailed explanation.   Written for practicing engineers in need of practical knowledge about the design and implementation of networks-on-chip; Includes tutorial-like details to introduce readers to a diverse range of NoC designs, as well as in-depth analysis for designers with NoC experience to explore advanced issues; Describes a variety of on-chip communication architectures, including a novel bi-directional communication channel NoC.     From the Foreword: Overall this book shows important advances over the...

  20. Kinerja Pengeringan Chip Ubi Kayu

    Directory of Open Access Journals (Sweden)

    Sandi Asmara

    2010-10-01

    Full Text Available Lampung Province is the largest producer of cassava in Indonesia. Cassava has a weakness that is easily damaged and could not be stored longer. To overcome this, there is a need of an effective drying process so that cassava can be processed into other materials of lower power use as well as its economic value. A hybrid drying system is one solution to resolve the issue. The purpose of this research is to study the performance of drying cassava chips by using a hybrid type of dryer rack. The process of drying cassava chips made using a three-stage treatments with three replicates with the input load of 30 kg of cassava chips. The results showed that the pattern of decline in water levels in each treatment is uneven. The time needed to dry cassava chips to reach the water content of 10% - 12% in the drying of materials using sunlight for 18 hours, using electrical energy for 16 hours and use the energy of sunlight and electricity for 12 hours. The higher temperatures produced the shorter the time required in the drying process. Electrical energy required for the drying process using electric energy was 91 440 kJ and drying using electrical energy and sunlight was 68600 kJ.

  1. Fiber cavities for atom chips

    OpenAIRE

    Klappauf, B.G.; Horak, P.; Kazansky, P. G.

    2003-01-01

    We present experimental realizations of several micro-cavities, constructed from standard fiber optic components, which meet the theoretical criteria for single atom detection from laser-cooled samples. We discuss integration of these cavities into state-of-the-art 'atom chips'.

  2. FERMI multi-chip module

    CERN Multimedia

    This FERMI multi-chip module contains five million transistors. 25 000 of these modules will handle the flood of information through parts of the ATLAS and CMS detectors at the LHC. To select interesting events for recording, crucial decisions are taken before the data leaves the detector. FERMI modules are being developed at CERN in partnership with European industry.

  3. Tunable on chip optofluidic laser

    DEFF Research Database (Denmark)

    Bakal, Avraham; Vannahme, Christoph; Kristensen, Anders;

    2015-01-01

    A chip scale tunable laser in the visible spectral band is realized by generating a periodic droplet array inside a microfluidic channel. Combined with a gain medium within the droplets, the periodic structure provides the optical feedback of the laser. By controlling the pressure applied to two...

  4. Single cell electroporation on chip

    NARCIS (Netherlands)

    Valero, Ana

    2006-01-01

    In this thesis the results of the development of microfluidic cell trap devices for single cell electroporation are described, which are to be used for gene transfection. The performance of two types of Lab-on-a-Chip trapping devices was tested using beads and cells, whereas the functionality for si

  5. Silicon ball grid array chip carrier

    Science.gov (United States)

    Palmer, David W.; Gassman, Richard A.; Chu, Dahwey

    2000-01-01

    A ball-grid-array integrated circuit (IC) chip carrier formed from a silicon substrate is disclosed. The silicon ball-grid-array chip carrier is of particular use with ICs having peripheral bond pads which can be reconfigured to a ball-grid-array. The use of a semiconductor substrate such as silicon for forming the ball-grid-array chip carrier allows the chip carrier to be fabricated on an IC process line with, at least in part, standard IC processes. Additionally, the silicon chip carrier can include components such as transistors, resistors, capacitors, inductors and sensors to form a "smart" chip carrier which can provide added functionality and testability to one or more ICs mounted on the chip carrier. Types of functionality that can be provided on the "smart" chip carrier include boundary-scan cells, built-in test structures, signal conditioning circuitry, power conditioning circuitry, and a reconfiguration capability. The "smart" chip carrier can also be used to form specialized or application-specific ICs (ASICs) from conventional ICs. Types of sensors that can be included on the silicon ball-grid-array chip carrier include temperature sensors, pressure sensors, stress sensors, inertia or acceleration sensors, and/or chemical sensors. These sensors can be fabricated by IC processes and can include microelectromechanical (MEM) devices.

  6. Infrared vertically-illuminated photodiode for chip alignment feedback

    Science.gov (United States)

    Alloatti, L.; Ram, R. J.

    2016-08-01

    We report on vertically-illuminated photodiodes fabricated in the GlobalFoundries 45nm 12SOI node and on a packaging concept for optically-interconnected chips. The photodiodes are responsive at 1180 nm -a wavelength currently used in chip-to-chip communications. They have further a wide field-of-view which enables chip-to-board positional feedback in chip-board assemblies. Monolithic integration enables on-chip processing of the positional data.

  7. Infrared vertically-illuminated photodiode for chip alignment feedback

    CERN Document Server

    Alloatti, Luca

    2016-01-01

    We report on vertically-illuminated photodiodes fabricated in the GlobalFoundries 45nm 12SOI node and on a packaging concept for optically-interconnected chips. The photodiodes are responsive at 1180 nm, a wavelength currently used in chip-to-chip communications. They have further a wide field-of-view which enables chip-to-board positional feedback in chip-board assemblies. Monolithic integration enables on-chip processing of the positional data.

  8. Photonic network-on-chip design

    CERN Document Server

    Bergman, Keren; Biberman, Aleksandr; Chan, Johnnie; Hendry, Gilbert

    2013-01-01

    This book provides a comprehensive synthesis of the theory and practice of photonic devices for networks-on-chip. It outlines the issues in designing photonic network-on-chip architectures for future many-core high performance chip multiprocessors. The discussion is built from the bottom up: starting with the design and implementation of key photonic devices and building blocks, reviewing networking and network-on-chip theory and existing research, and finishing with describing various architectures, their characteristics, and the impact they will have on a computing system. After acquainting

  9. Wax-bonding 3D microfluidic chips

    KAUST Repository

    Gong, Xiuqing

    2013-10-10

    We report a simple, low-cost and detachable microfluidic chip incorporating easily accessible paper, glass slides or other polymer films as the chip materials along with adhesive wax as the recycling bonding material. We use a laser to cut through the paper or film to form patterns and then sandwich the paper and film between glass sheets or polymer membranes . The hot-melt adhesive wax can realize bridge bonding between various materials, for example, paper, polymethylmethacrylate (PMMA) film, glass sheets, or metal plate. The bonding process is reversible and the wax is reusable through a melting and cooling process. With this process, a three-dimensional (3D) microfluidic chip is achievable by vacuating and venting the chip in a hot-water bath. To study the biocompatibility and applicability of the wax-based microfluidic chip, we tested the PCR compatibility with the chip materials first. Then we applied the wax-paper based microfluidic chip to HeLa cell electroporation (EP ). Subsequently, a prototype of a 5-layer 3D chip was fabricated by multilayer wax bonding. To check the sealing ability and the durability of the chip, green fluorescence protein (GFP) recombinant Escherichia coli (E. coli) bacteria were cultured, with which the chemotaxis of E. coli was studied in order to determine the influence of antibiotic ciprofloxacin concentration on the E. coli migration.

  10. On-chip plasmonic spectrometer.

    Science.gov (United States)

    Tsur, Yuval; Arie, Ady

    2016-08-01

    We report a numerical and experimental study of an on-chip optical spectrometer, utilizing propagating surface plasmon polaritons in the telecom spectral range. The device is based on two holographic gratings, one for coupling, and the other for decoupling free-space radiation with the surface plasmons. This 800 μm×100 μm on-chip spectrometer resolves 17 channels spectrally separated by 3.1 nm, spanning a freely tunable spectral window, and is based on standard lithography fabrication technology. We propose two potential applications for this new device; the first employs the holographic control over the amplitude and phase of the input spectrum, for intrinsically filtering unwanted frequencies, like pump radiation in Raman spectroscopy. The second prospect utilizes the unique plasmonic field enhancement at the metal-dielectric boundary for the spectral analysis of very small samples (e.g., Mie scatterers) placed between the two gratings.

  11. Mimosa 32-ter Chip Characterisation

    CERN Document Server

    Behera, Arabinda

    2013-01-01

    The Inner Tracking System (ITS) is a very important part of the ALICE detector. Present ITS is made up of 6 coaxial layers of silicon detectors (2 SPD, 2 SDD and 2 SSD). This system has a lot of limitations. Its tracking efficiency and resolution is low. Its readout rate is also very slow. Its not possible to study charm and beauty baryons and mesons with this system. So the upcoming ITS Upgrade plan will try to overcome these shortcomings. A very crucial part in this plan is to replace the existing hybrid sensors by new and advanced Monolithic Active Pixel Sensors(MAPS). In MAPS the sensor and the electronics are embedded in the same chip. The MAPS will reduce the material budget, increase the readout rate and enhance the tracking efficiency and momentum resolution. In this report I will present the results for the Characterisation of MIMOSA 32-ter chip, which is a MAPS. My main aim is to calculate the Charge Collection Efficiency of different sectors of the chip and compare between them. And most importa...

  12. Radiation Behavior of Analog Neural Network Chip

    Science.gov (United States)

    Langenbacher, H.; Zee, F.; Daud, T.; Thakoor, A.

    1996-01-01

    A neural network experiment conducted for the Space Technology Research Vehicle (STRV-1) 1-b launched in June 1994. Identical sets of analog feed-forward neural network chips was used to study and compare the effects of space and ground radiation on the chips. Three failure mechanisms are noted.

  13. Microluminometer chip and method to measure bioluminescence

    Science.gov (United States)

    Simpson, Michael L [Knoxville, TN; Paulus, Michael J [Knoxville, TN; Sayler, Gary S [Blaine, TN; Applegate, Bruce M [West Lafayette, IN; Ripp, Steven A [Knoxville, TN

    2008-05-13

    An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on the chip for processing the photocurrent. A distributed electrode configuration including a plurality of spaced apart electrodes disposed on an active region of the photodetector is preferably used to raise efficiency.

  14. Superconducting chip receivers for imaging application

    NARCIS (Netherlands)

    Shitov, SV; Koshelets, VP; Ermakov, AB; Filippenko, LV; Baryshev, AM; Luinge, W; Gao, [No Value

    1999-01-01

    Experimental details of a unique superconducting imaging array receiver are discussed. Each pixel contains an internally pumped receiver chip mounted on the back of the elliptical microwave lens. Each chip comprises a quasi-optical SIS mixer integrated with a superconducting flux-flow oscillator (FF

  15. Simple photolithographic rapid prototyping of microfluidic chips

    DEFF Research Database (Denmark)

    Kunstmann-Olsen, Casper; Hoyland, James; Rubahn, Horst-Günter

    2012-01-01

    Vi præsenterer en simpel metode til at producere støbeforme til støbning af PDMS mikrofluide chips vha. fotolitografi, med 35mm fotonegativer som masker. Vi demonstrer metodens muligheder og begrænsninger. Vi har optimeret processen til at fremstille planare lab-on-a-chip strukturer med meget høj...

  16. Least cost supply strategies for wood chips

    DEFF Research Database (Denmark)

    Möller, Bernd

    The abstract presents a study based on a geographical information system, which produce  cost-supply curves by location for forest woods chips in Denmark.......The abstract presents a study based on a geographical information system, which produce  cost-supply curves by location for forest woods chips in Denmark....

  17. Assembly, chip and method of operating

    NARCIS (Netherlands)

    Reefman, D.; Roozeboom, F.; Klootwijk, J.H.

    2012-01-01

    The chip comprises a network of trench capacitors and an inductor, wherein the trench capacitors are coupled in parallel with a pattern of interconnects that is designed so as to limit generation of eddy current induced by the inductor in the interconnects. This allows the use of the chip as a porti

  18. Teaching Quality Control with Chocolate Chip Cookies

    Science.gov (United States)

    Baker, Ardith

    2014-01-01

    Chocolate chip cookies are used to illustrate the importance and effectiveness of control charts in Statistical Process Control. By counting the number of chocolate chips, creating the spreadsheet, calculating the control limits and graphing the control charts, the student becomes actively engaged in the learning process. In addition, examining…

  19. Carbon Nanotube Amperometric Chips with Pneumatic Micropumps

    Science.gov (United States)

    Tsujita, Yuichi; Maehashi, Kenzo; Matsumoto, Kazuhiko; Chikae, Miyuki; Torai, Soichiro; Takamura, Yuzuru; Tamiya, Eiichi

    2008-04-01

    We fabricated carbon nanotube (CNT) amperometric chips with pneumatic micropumps by the combination of amperometric biosensors based on CNT-arrayed electrodes and microchannels with pneumatic micropumps made of poly(dimethylsiloxane). On the chip, phosphate buffer solution and potassium ferricyanide, K3[Fe(CN)6], were introduced into the CNT electrodes using each pneumatic micropump and electrochemically measured by differential pulse voltammetry. The results indicate that our chip can automatically exchange reagents on the CNT electrodes and clearly detect molecules. Moreover, by modifying the CNT electrodes with enzyme glucose oxidase, glucose molecules could be detected using our chips by cyclic voltammetry and chronoamperometry. We conclude that microfluidic chips with CNT-arrayed electrodes are a promising candidate for the development of hand-held electrochemical biosensors.

  20. Ex Vacuo Atom Chip Bose-Einstein Condensate (BEC)

    CERN Document Server

    Squires, Matthew B; Kasch, Brian; Stickney, James A; Erickson, Christopher J; Crow, Jonathan A R; Carlson, Evan J; Burke, John H

    2016-01-01

    Ex vacuo atom chips, used in conjunction with a custom thin walled vacuum chamber, have enabled the rapid replacement of atom chips for magnetically trapped cold atom experiments. Atoms were trapped in $>2$ kHz magnetic traps created using high power atom chips. The thin walled vacuum chamber allowed the atoms to be trapped $\\lesssim1$ mm from the atom chip conductors which were located outside of the vacuum system. Placing the atom chip outside of the vacuum simplified the electrical connections and improved thermal management. Using a multi-lead Z-wire chip design, a Bose-Einstein condensate was produced with an external atom chip. Vacuum and optical conditions were maintained while replacing the Z-wire chip with a newly designed cross-wire chip. The atom chips were exchanged and an initial magnetic trap was achieved in less than three hours.

  1. 75 FR 30046 - Medicaid and CHIP Programs; Meeting of the CHIP Working Group-June 14, 2010

    Science.gov (United States)

    2010-05-28

    ... published on May 1, 2009 (74 FR 20323). The CHIP Working Group will meet two times to develop a model... Administration Medicaid and CHIP Programs; Meeting of the CHIP Working Group-- June 14, 2010 AGENCY: Centers for... the second meeting of the Medicaid, Children's Health Insurance Program (``CHIP''), and...

  2. A multi-year survey of stem-end chip defect in chipping potatoes (Solanum tuberosum L.)

    Science.gov (United States)

    One of the most serious tuber quality concerns of US chip potato growers is stem-end chip defect, which is defined as a localized post-fry discoloration in and adjacent to the vasculature on the stem end portion of potato chips. The incidence and severity of stem-end chip defect vary with growing lo...

  3. Self-powered integrated systems-on-chip (energy chip)

    KAUST Repository

    Hussain, Muhammad Mustafa

    2010-04-23

    In today\\'s world, consumer driven technology wants more portable electronic gadgets to be developed, and the next big thing in line is self-powered handheld devices. Therefore to reduce the power consumption as well as to supply sufficient power to run those devices, several critical technical challenges need to be overcome: a. Nanofabrication of macro/micro systems which incorporates the direct benefit of light weight (thus portability), low power consumption, faster response, higher sensitivity and batch production (low cost). b. Integration of advanced nano-materials to meet the performance/cost benefit trend. Nano-materials may offer new functionalities that were previously underutilized in the macro/micro dimension. c. Energy efficiency to reduce power consumption and to supply enough power to meet that low power demand. We present a pragmatic perspective on a self-powered integrated System on Chip (SoC). We envision the integrated device will have two objectives: low power consumption/dissipation and on-chip power generation for implementation into handheld or remote technologies for defense, space, harsh environments and medical applications. This paper provides insight on materials choices, intelligent circuit design, and CMOS compatible integration.

  4. Attachment method for stacked integrated circuit (IC) chips

    Energy Technology Data Exchange (ETDEWEB)

    Bernhardt, Anthony F. (Berkeley, CA); Malba, Vincent (Livermore, CA)

    1999-01-01

    An attachment method for stacked integrated circuit (IC) chips. The method involves connecting stacked chips, such as DRAM memory chips, to each other and/or to a circuit board. Pads on the individual chips are rerouted to form pads on the side of the chip, after which the chips are stacked on top of each other whereby desired interconnections to other chips or a circuit board can be accomplished via the side-located pads. The pads on the side of a chip are connected to metal lines on a flexible plastic tape (flex) by anisotropically conductive adhesive (ACA). Metal lines on the flex are likewise connected to other pads on chips and/or to pads on a circuit board. In the case of a stack of DRAM chips, pads to corresponding address lines on the various chips may be connected to the same metal line on the flex to form an address bus. This method has the advantage of reducing the number of connections required to be made to the circuit board due to bussing; the flex can accommodate dimensional variation in the alignment of chips in the stack; bonding of the ACA is accomplished at low temperature and is otherwise simpler and less expensive than solder bonding; chips can be bonded to the ACA all at once if the sides of the chips are substantially coplanar, as in the case for stacks of identical chips, such as DRAM.

  5. Attachment method for stacked integrated circuit (IC) chips

    Energy Technology Data Exchange (ETDEWEB)

    Bernhardt, A.F.; Malba, V.

    1999-08-03

    An attachment method for stacked integrated circuit (IC) chips is disclosed. The method involves connecting stacked chips, such as DRAM memory chips, to each other and/or to a circuit board. Pads on the individual chips are rerouted to form pads on the side of the chip, after which the chips are stacked on top of each other whereby desired interconnections to other chips or a circuit board can be accomplished via the side-located pads. The pads on the side of a chip are connected to metal lines on a flexible plastic tape (flex) by anisotropically conductive adhesive (ACA). Metal lines on the flex are likewise connected to other pads on chips and/or to pads on a circuit board. In the case of a stack of DRAM chips, pads to corresponding address lines on the various chips may be connected to the same metal line on the flex to form an address bus. This method has the advantage of reducing the number of connections required to be made to the circuit board due to bussing; the flex can accommodate dimensional variation in the alignment of chips in the stack; bonding of the ACA is accomplished at low temperature and is otherwise simpler and less expensive than solder bonding; chips can be bonded to the ACA all at once if the sides of the chips are substantially coplanar, as in the case for stacks of identical chips, such as DRAM. 12 figs.

  6. Microchannel cooling of face down bonded chips

    Science.gov (United States)

    Bernhardt, Anthony F.

    1993-01-01

    Microchannel cooling is applied to flip-chip bonded integrated circuits, in a manner which maintains the advantages of flip-chip bonds, while overcoming the difficulties encountered in cooling the chips. The technique is suited to either multichip integrated circuit boards in a plane, or to stacks of circuit boards in a three dimensional interconnect structure. Integrated circuit chips are mounted on a circuit board using flip-chip or control collapse bonds. A microchannel structure is essentially permanently coupled with the back of the chip. A coolant delivery manifold delivers coolant to the microchannel structure, and a seal consisting of a compressible elastomer is provided between the coolant delivery manifold and the microchannel structure. The integrated circuit chip and microchannel structure are connected together to form a replaceable integrated circuit module which can be easily decoupled from the coolant delivery manifold and the circuit board. The coolant supply manifolds may be disposed between the circuit boards in a stack and coupled to supplies of coolant through a side of the stack.

  7. Three dimensional, multi-chip module

    Science.gov (United States)

    Bernhardt, Anthony F.; Petersen, Robert W.

    1993-01-01

    A plurality of multi-chip modules are stacked and bonded around the perimeter by sold-bump bonds to adjacent modules on, for instance, three sides of the perimeter. The fourth side can be used for coolant distribution, for more interconnect structures, or other features, depending on particular design considerations of the chip set. The multi-chip modules comprise a circuit board, having a planarized interconnect structure formed on a first major surface, and integrated circuit chips bonded to the planarized interconnect surface. Around the periphery of each circuit board, long, narrow "dummy chips" are bonded to the finished circuit board to form a perimeter wall. The wall is higher than any of the chips on the circuit board, so that the flat back surface of the board above will only touch the perimeter wall. Module-to-module interconnect is laser-patterned o the sides of the boards and over the perimeter wall in the same way and at the same time that chip to board interconnect may be laser-patterned.

  8. Physiologically relevant organs on chips.

    Science.gov (United States)

    Yum, Kyungsuk; Hong, Soon Gweon; Healy, Kevin E; Lee, Luke P

    2014-01-01

    Recent advances in integrating microengineering and tissue engineering have generated promising microengineered physiological models for experimental medicine and pharmaceutical research. Here we review the recent development of microengineered physiological systems, or also known as "ogans-on-chips", that reconstitute the physiologically critical features of specific human tissues and organs and their interactions. This technology uses microengineering approaches to construct organ-specific microenvironments, reconstituting tissue structures, tissue-tissue interactions and interfaces, and dynamic mechanical and biochemical stimuli found in specific organs, to direct cells to assemble into functional tissues. We first discuss microengineering approaches to reproduce the key elements of physiologically important, dynamic mechanical microenvironments, biochemical microenvironments, and microarchitectures of specific tissues and organs in microfluidic cell culture systems. This is followed by examples of microengineered individual organ models that incorporate the key elements of physiological microenvironments into single microfluidic cell culture systems to reproduce organ-level functions. Finally, microengineered multiple organ systems that simulate multiple organ interactions to better represent human physiology, including human responses to drugs, is covered in this review. This emerging organs-on-chips technology has the potential to become an alternative to 2D and 3D cell culture and animal models for experimental medicine, human disease modeling, drug development, and toxicology.

  9. Imaging Cold Molecules on a Chip

    CERN Document Server

    Marx, S; Abel, M J; Zehentbauer, T; Meijer, G; Santambrogio, G

    2013-01-01

    We present the integrated imaging of cold molecules in a microchip environment. The on-chip de- tection is based on REMPI, which is quantum-state-selective and generally applicable. We demon- strate and characterize time-resolved spatial imaging and subsequently use it to analyze the effect of a phase-space manipulation sequence aimed at compressing the velocity distribution of a molec- ular ensemble with a view to future high-resolution spectroscopic studies. The realization of such on-chip measurements adds the final fundamental component to the molecule chip, offering a new and promising route for investigating cold molecules.

  10. Flit Synchronous Aelite Network on Chip

    OpenAIRE

    Subburaman, Mahesh Balaji

    2008-01-01

      The deep sub micron process technology and application convergence increases the design challenges in System-on-Chip (SoC). The traditional bus based on chip communication are not scalable and fails to deliver the performance requirements of the complex SoC. The Network on Chip (NoC) has been emerged as a solution to address these complexities of a efficient, high performance, scalable SoC design. The Aethereal NoC provides the latency and throughput bounds by pipelined timedivision multipl...

  11. METAL CHIP HEATING PROCESS INVESTIGATION (Part 3

    Directory of Open Access Journals (Sweden)

    O. M. Dyakonov

    2008-01-01

    Full Text Available The numerical solution algorithm of mathematical model of metal chip heating process in continuous muffle furnace and computer calculation program that allow to determine the heat- and mass transfer parameters have been worked out. The numerical modeling has been performed for three different lubricant-coolant compositions and six different furnace heights (all together 18 variants at the furnace productivity2000 kgof chip per hour. The main characteristics of chip heating process have been calculated. There was determined that the optimum furnace height at the point of its highest energy efficiency equals4,5 m. 

  12. ToxChip and its applications

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@\tToxChip is the molecular biological technology which has been developed based on genome and DNA microarray technologies. It will be able to make the sci-entists evaluate the toxicity of extraneous toxicants at the molecular level. ToxChip was successfully developed by a group of the National Institute of Environmental Health Sciences (NIEHS) researchers in the United States in 1999[1]. The technology bears revolutionary significance on the traditional toxicology. It foretells the epoch in which DNA effects of environmental dangers and toxi-cants can be made certain rapidly and efficiently to fall. ToxChip will pioneer novel approaches for medicine, environmental and ecological toxicologies.

  13. An analog CMOS chip set for neural networks with arbitrary topologies

    OpenAIRE

    Lansner, John; Lehmann, Torsten

    1993-01-01

    An analog CMOS chip set for implementations of artificial neural networks (ANNs) has been fabricated and tested. The chip set consists of two cascadable chips: a neuron chip and a synapse chip. Neurons on the neuron chips can be interconnected at random via synapses on the synapse chips thus implementing an ANN with arbitrary topology. The neuron test chip contains an array of 4 neurons with well defined hyperbolic tangent activation functions which is implemented by using parasitic lateral b...

  14. Assessment of Deformation of Shear Localized Chip in High Speed Machining

    Institute of Scientific and Technical Information of China (English)

    T; C; LEE; W; S; LAU; S; K; CHAN

    2002-01-01

    As the cutting speed goes higher, the mechanism of chip deformation will be changed significantly, i.e., continuous chip in low cutting speed will shift to serrated chip with shear localization. For the shear localized chip, the parameters used to assess the chip deformation for continuous chip, such as shorten coefficient ξ, shear angle φ and shear strain ε, can not describe the chip deformation correctly or comprehensively. This paper deals with the assessment of chip deformation of shear localization. Th...

  15. On-chip power delivery and management

    CERN Document Server

    Vaisband, Inna P; Popovich, Mikhail; Mezhiba, Andrey V; Köse, Selçuk; Friedman, Eby G

    2016-01-01

    This book describes methods for distributing power in high speed, high complexity integrated circuits with power levels exceeding many tens of watts and power supplies below a volt. It provides a broad and cohesive treatment of power delivery and management systems and related design problems, including both circuit network models and design techniques for on-chip decoupling capacitors, providing insight and intuition into the behavior and design of on-chip power distribution systems. Organized into subareas to provide a more intuitive flow to the reader, this fourth edition adds more than a hundred pages of new content, including inductance models for interdigitated structures, design strategies for multi-layer power grids, advanced methods for efficient power grid design and analysis, and methodologies for simultaneously placing on-chip multiple power supplies and decoupling capacitors. The emphasis of this additional material is on managing the complexity of on-chip power distribution networks.

  16. Medicaid CHIP Environmental Scanning and Program Char...

    Data.gov (United States)

    U.S. Department of Health & Human Services — ESPC development is sponsored by the CMS Center for Medicare and Medicaid Innovation in partnership with the Center for Medicaid and CHIP Services (CMCS) under the...

  17. Spacecraft on a Chip Development Project

    Data.gov (United States)

    National Aeronautics and Space Administration — System on a chip is a method to increase engineering efficiency. State of the art components are increasing in gate count as expected according to Moore’s...

  18. A Chip for an Implantable Neural Stimulator

    DEFF Research Database (Denmark)

    Gudnason, Gunnar; Bruun, Erik; Haugland, Morten

    2000-01-01

    This paper describes a chip for a multichannel neural stimulator for functional electrical stimulation (FES). The purpose of FES is to restore muscular control in disabled patients. The chip performs all the signal processing required in an implanted neural stimulator. The power and digital data...... transmission to the stimulator passes through a 5 MHz inductive link. From the signals transmitted to the stimulator, the chip is able to generate charge-balanced current pulses with a controllable length up to 256 µs and an amplitude up to 2 mA, for stimulation of nerve fibers. The quiescent current...... consumption of the chip is approx. 650 µA at supply voltages of 6–12 V, and its size is 3.9×3.5 mm2. It has 4 output channels for use in a multipolar cuff electrode....

  19. Open Tiled Manycore System-on-Chip

    OpenAIRE

    Wallentowitz, Stefan; Wagner, Philipp; Tempelmeier, Michael; Wild, Thomas; Herkersdorf, Andreas

    2013-01-01

    Manycore System-on-Chip include an increasing amount of processing elements and have become an important research topic for improvements of both hardware and software. While research can be conducted using system simulators, prototyping requires a variety of components and is very time consuming. With the Open Tiled Manycore System-on-Chip (OpTiMSoC) we aim at building such an environment for use in our and other research projects as prototyping platform. This paper describes the project goal...

  20. Surface enhanced raman spectroscopy on chip

    DEFF Research Database (Denmark)

    Hübner, Jörg; Anhøj, Thomas Aarøe; Zauner, Dan;

    2007-01-01

    In this paper we report low resolution surface enhanced Raman spectra (SERS) conducted with a chip based spectrometer. The flat field spectrometer presented here is fabricated in SU-8 on silicon, showing a resolution of around 3 nm and a free spectral range of around 100 nm. The output facet...... fiber. The obtained spectra show that chip based spectrometer together with the SERS active surface can be used as Raman sensor....

  1. Link between chips and cutting moments evolution

    CERN Document Server

    Cahuc, Olivier; Gérard, Alain; 10.4028/WWW.scientific.net/AMR.423.89

    2012-01-01

    The better understanding of the material cutting process has been shown with the benefit of the forces and moments measurement since some years ago. In paper, simultaneous six mechanical components and chip orientation measurements were realized during turning tests. During these tests, the influence of the depth of cut or feed rate has been observed and a link between the chip orientation and the moment vector orientation or the central axis characteristics has been shown.

  2. On-chip spiral spectrometer

    CERN Document Server

    Redding, Brandon; Bromberg, Yaron; Sarma, Raktim; Cao, Hui

    2016-01-01

    We designed an on-chip spectrometer based on an evanescently-coupled multimode spiral waveguide. Interference between the modes in the waveguide forms a wavelength-dependent speckle pattern which can be used as a fingerprint to identify the input wavelength after calibration. Evanescent coupling between neighboring arms of the spiral enhances the temporal spread of light propagating through the spiral, leading to a dramatic increase in the spectral resolution. Experimentally, we demonstrated that a 250 {\\mu}m radius spiral spectrometer provides a resolution of 0.01 nm at a wavelength of 1520 nm. Spectra containing 40 independent spectral channels can be recovered simultaneously and the operation bandwidth can be increased further when measuring sparse spectra.

  3. Chip integrated fuel cell accumulator

    Science.gov (United States)

    Frank, M.; Erdler, G.; Frerichs, H.-P.; Müller, C.; Reinecke, H.

    A unique new design of a chip integrated fuel cell accumulator is presented. The system combines an electrolyser and a self-breathing polymer electrolyte membrane (PEM) fuel cell with integrated palladium hydrogen storage on a silicon substrate. Outstanding advantages of this assembly are the fuel cell with integrated hydrogen storage, the possibility of refuelling it by electrolysis and the opportunity of simply refilling the electrolyte by adding water. By applying an electrical current, wiring the palladium hydrogen storage as cathode and the counter-electrode as anode, the electrolyser produces hydrogen at the palladium surface and oxygen at the electrolyser cell anode. The generated hydrogen is absorbed by the palladium electrode and the hydrogen storage is refilled consequently enabling the fuel cell to function.

  4. Fabrication technology of integrated fiber microfluidic electrophoresis chip

    Institute of Scientific and Technical Information of China (English)

    LI MengChun

    2007-01-01

    The technology of PCB was used to fabricate the chip mould, and the microfluidic electrophoresis chip was fabricated with PDMS material. The fiber integrated on the chip was used as the transmission medium, so the light spot size was near the depth of microchannel. The detection sensitivity was improved, and the optical focusing system was spared. The fabrication process, sealing methods and structure characteristic of PDMS microfluidic electrophoresis chips were discussed. The experiment was achieved by using the fabricated chip to separate FITC fluorescein and FITC-labeled amino acid mixture reagent, and the feasibility of the chip was validated.

  5. On-chip positionable photonic waveguides for chip-to-chip optical interconnects

    Science.gov (United States)

    Peters, Tjitte-Jelte; Tichem, Marcel

    2016-05-01

    This paper reports on the progress related to a multichannel photonic alignment concept, aiming for sub-micrometer precision in the alignment of the waveguides of two photonic integrated circuits (PICs). The concept consists of two steps: chip-to-chip positioning and chip bonding provide a coarse alignment after which waveguide-to-waveguide positioning and fixing result in a fine alignment. For the waveguide-to-waveguide alignment, an alignment functionality is developed and integrated in one of the PICs, consisting of mechanically flexible waveguides and MEMS actuators. This paper reports on the fabrication and characterization of a mechanically flexible waveguide array that can be positioned by two out-of-plane actuators. Thermal actuators are integrated with mechanically flexible waveguide beams to enable positioning them with high precision. By adding a poly-Si pattern on top of SiO2 beams, an out-of-plane bimorph actuator can be realized. An analytical model enables estimating the curvature and the deflection of a single bimorph beam. Acquiring a small initial deflection while having a large motion range of the actuator proves to have conflicting demands on the poly-Si/SiO2 thickness ratio. In this paper, we show that suspended waveguide arrays with integrated alignment functionality have an initial deflection- they curl up- due to residual stress in the materials. The actuators can be operated using a driving voltage between 0V to 45V, corresponding to ~50mW. Using higher voltages brings the risk of permanently changing the material properties of the heaters. The actuators can accomplish an out-of-plane crossbar translation up to 6.5 μm at ~50mW as well as a rotation around the propagation direction of the light ranging from -0:1° to 0.1°. At a constant actuation power of ~50mW, the crossbar shows a drift in vertical deflection of 0.16 μm over a time of 30 min.

  6. On-chip liquid storage and dispensing for lab-on-a-chip applications

    International Nuclear Information System (INIS)

    This work presents novel components for on-chip storage and dispensing inside a lab-on-a-chip (LOC) for applications in immunoassay point-of-care testing (POCT), where incubation and washing steps are essential. It involves easy-to-use on-chip solutions for the sequential thermo-hydraulic actuation of liquids. The novel concept of combining the use of a rubber plug, both as a non-return valve cap and as a liquid injection interface of a sealed reservoir, allows simple filling of a sterilized cavity, as well as the storage and dispensing of reagent and washing buffer liquids. Segmenting the flow with air spacers enables effective rinsing and the use of small volumes of on-chip stored liquids. The chip uses low-resistance resistors as heaters in the paraffin actuator, providing the low-voltage actuation that is preferred for handheld battery driven instruments

  7. Advanced Flip Chips in Extreme Temperature Environments

    Science.gov (United States)

    Ramesham, Rajeshuni

    2010-01-01

    The use of underfill materials is necessary with flip-chip interconnect technology to redistribute stresses due to mismatching coefficients of thermal expansion (CTEs) between dissimilar materials in the overall assembly. Underfills are formulated using organic polymers and possibly inorganic filler materials. There are a few ways to apply the underfills with flip-chip technology. Traditional capillary-flow underfill materials now possess high flow speed and reduced time to cure, but they still require additional processing steps beyond the typical surface-mount technology (SMT) assembly process. Studies were conducted using underfills in a temperature range of -190 to 85 C, which resulted in an increase of reliability by one to two orders of magnitude. Thermal shock of the flip-chip test articles was designed to induce failures at the interconnect sites (-40 to 100 C). The study on the reliability of flip chips using underfills in the extreme temperature region is of significant value for space applications. This technology is considered as an enabling technology for future space missions. Flip-chip interconnect technology is an advanced electrical interconnection approach where the silicon die or chip is electrically connected, face down, to the substrate by reflowing solder bumps on area-array metallized terminals on the die to matching footprints of solder-wettable pads on the chosen substrate. This advanced flip-chip interconnect technology will significantly improve the performance of high-speed systems, productivity enhancement over manual wire bonding, self-alignment during die joining, low lead inductances, and reduced need for attachment of precious metals. The use of commercially developed no-flow fluxing underfills provides a means of reducing the processing steps employed in the traditional capillary flow methods to enhance SMT compatibility. Reliability of flip chips may be significantly increased by matching/tailoring the CTEs of the substrate

  8. Experiment list: SRX821806 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnolog...ies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/each

  9. Experiment list: SRX821818 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available =PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnolo...gies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/eac

  10. Experiment list: SRX180159 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available sd || cell type=hemogenic endothelium || chip antibody=CEBPb || chip antibody vendor=santa cruz biotechnol...ogy http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/eachData/bw/SRX180159.bw http://

  11. Novel High Pressure Pump-on-a-Chip Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — HJ Science & Technology, Inc proposes to develop a novel high pressure "pump-on-a-chip" and "valve-on-a-chip" microfluidic technology for NASA planetary science...

  12. Experiment list: SRX367328 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nology) || sirna transfection=siCTL http://dbarchive.bio...=HEK293T cell || cell line=Human Embryonic Kidney 293 cells || chip antibody=CDK9 || chip antibody details=2316S (Cell Signaling Tech

  13. Experiment list: SRX367330 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nology) || sirna transfection=siBrd4 http://dbarchive.bi...=HEK293T cell || cell line=Human Embryonic Kidney 293 cells || chip antibody=CDK9 || chip antibody details=2316S (Cell Signaling Tech

  14. Experiment list: SRX367329 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available hnology) || sirna transfection=siJMJD6 http://dbarchive....e=HEK293T cell || cell line=Human Embryonic Kidney 293 cells || chip antibody=CDK9 || chip antibody details=2316S (Cell Signaling Tec

  15. Experiment list: SRX821809 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnolog...ies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/each

  16. Experiment list: SRX821821 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnolog...ies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/each

  17. Experiment list: SRX821815 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnolog...ies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/each

  18. Experiment list: SRX821812 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available =PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnolo...gies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/eac

  19. Experiment list: SRX821820 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnolog...ies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/each

  20. Experiment list: SRX112178 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available line=OS25 ES cells || chip antibody=8WG16 (MMS-126R, Covance) || chip antibody manufacturer=Covance || chromatin=Fixed || beads=Magn...etic beads http://dbarchive.biosciencedbc.jp/kyushu-u/mm

  1. Materials for microfluidic chip fabrication.

    Science.gov (United States)

    Ren, Kangning; Zhou, Jianhua; Wu, Hongkai

    2013-11-19

    Through manipulating fluids using microfabricated channel and chamber structures, microfluidics is a powerful tool to realize high sensitive, high speed, high throughput, and low cost analysis. In addition, the method can establish a well-controlled microenivroment for manipulating fluids and particles. It also has rapid growing implementations in both sophisticated chemical/biological analysis and low-cost point-of-care assays. Some unique phenomena emerge at the micrometer scale. For example, reactions are completed in a shorter amount of time as the travel distances of mass and heat are relatively small; the flows are usually laminar; and the capillary effect becomes dominant owing to large surface-to-volume ratios. In the meantime, the surface properties of the device material are greatly amplified, which can lead to either unique functions or problems that we would not encounter at the macroscale. Also, each material inherently corresponds with specific microfabrication strategies and certain native properties of the device. Therefore, the material for making the device plays a dominating role in microfluidic technologies. In this Account, we address the evolution of materials used for fabricating microfluidic chips, and discuss the application-oriented pros and cons of different materials. This Account generally follows the order of the materials introduced to microfluidics. Glass and silicon, the first generation microfluidic device materials, are perfect for capillary electrophoresis and solvent-involved applications but expensive for microfabriaction. Elastomers enable low-cost rapid prototyping and high density integration of valves on chip, allowing complicated and parallel fluid manipulation and in-channel cell culture. Plastics, as competitive alternatives to elastomers, are also rapid and inexpensive to microfabricate. Their broad variety provides flexible choices for different needs. For example, some thermosets support in-situ fabrication of

  2. Performance and Energy Efficient Network-on-Chip Architectures

    OpenAIRE

    Vangal, Sriram

    2007-01-01

    The scaling of MOS transistors into the nanometer regime opens the possibility for creating large Network-on-Chip (NoC) architectures containing hundreds of integrated processing elements with on-chip communication. NoC architectures, with structured on-chip networks are emerging as a scalable and modular solution to global communications within large systems-on-chip. NoCs mitigate the emerging wire-delay problem and addresses the need for substantial interconnect bandwidth by replacing today...

  3. Expression and significance of CHIP in canine mammary gland tumors.

    Science.gov (United States)

    Wang, Huanan; Yang, Xu; Jin, Yipeng; Pei, Shimin; Zhang, Di; Ma, Wen; Huang, Jian; Qiu, Hengbin; Zhang, Xinke; Jiang, Qiuyue; Sun, Weidong; Zhang, Hong; Lin, Degui

    2015-11-01

    CHIP (Carboxy terminus of Hsc70 Interacting Protein) is an E3 ubiquitin ligase that can induce ubiquitination and degradation of several oncogenic proteins. The expression of CHIP is frequently lower in human breast cancer than in normal breast tissue. However, the expression and role of CHIP in the canine mammary gland tumor (CMGT) remain unclear. We investigated the potential correlation between CHIP expression and mammary gland tumor prognosis in female dogs. CHIP expression was measured in 54 dogs by immunohistochemistry and real-time RT-PCR. CHIP protein expression was significantly correlated with the histopathological diagnosis, outcome of disease and tumor classification. The transcriptional level of CHIP was significantly higher in normal tissues (P=0.001) and benign tumors (P=0.009) than it in malignant tumors. CHIP protein expression was significantly correlated with the transcriptional level of CHIP (P=0.0102). The log-rank test survival curves indicated that patients with low expression of CHIP had shorter overall periods of survival than those with higher CHIP protein expression (P=0.050). Our data suggest that CHIP may play an important role in the formation and development of CMGTs and serve as a valuable prognostic marker and potential target for genetic therapy.

  4. A Neuron- and a Synapse Chip for Artificial Neural Networks

    DEFF Research Database (Denmark)

    Lansner, John; Lehmann, Torsten

    1992-01-01

    A cascadable, analog, CMOS chip set has been developed for hardware implementations of artificial neural networks (ANN's):I) a neuron chip containing an array of neurons with hyperbolic tangent activation functions and adjustable gains, and II) a synapse chip (or a matrix-vector multiplier) where...

  5. Packetizing OCP Transactions in the MANGO Network-on-Chip

    DEFF Research Database (Denmark)

    Bjerregaard, Tobias; Sparsø, Jens

    2006-01-01

    The scaling of CMOS technology causes a widening gap between the performance of on-chip communication and computation. This calls for a communication-centric design flow. The MANGO network-on-chip architecture enables globally asynchronous locally synchronous (GALS) system-on-chip design, while...

  6. Discovery Mondays: Chips with everything!

    CERN Multimedia

    2003-01-01

    Electronics to hear the sound of matter From the TV to the fridge, the wristwatch to the washing machine, hardly any consumer product in this day and age can escape the influence of electronics, and the ever more powerful microchip. So it's hardly surprising to learn that such sophisticated devices as particle detectors are bristling with the best and most powerful microchips technology has to offer! Particle detectors known as trackers are like 3-D digital cameras. They are used to detect the tracks of particles created in the accelerator and to pin down their momentum and thus their identity. A chip seen with a microscope.Come to Microcosm and see with your own eyes a silicon detector, packed full of electronic microchips. Get up closer with a microscope and admire the way in which the fine details of the etchings break down light. Further on, watch a TV as you've never done before - from the inside! Then try out our special simulation game that helps you understand the purpose of a particle detector. Bu...

  7. Modeling of chip bed packing in a continuous kraft cooking digester

    OpenAIRE

    Laakso, Sampsa

    2008-01-01

    This work focused on modeling of the chip bed packing phenomena in a continuous kraft cooking digester. A better understanding of chip bed packing would make it possible to optimize chip flow conditions in the digester, thereby ensuring uniform fiber quality and production efficiency. Chips are fed continuously into the digester, with the chip flow forming a solid bed. As the solid chip bed moves slowly downwards, cooking reactions proceed, which leads to softening of the chips. The soft...

  8. 75 FR 16149 - Medicaid and CHIP Programs; Meeting of the CHIP Working Group-April 26, 2010

    Science.gov (United States)

    2010-03-31

    ... nominations submitted in response to a Federal Register solicitation notice published on May 1, 2009 (74 FR... Administration Medicaid and CHIP Programs; Meeting of the CHIP Working Group-- April 26, 2010 AGENCIES: Centers... announces the first meeting of the Medicaid, Children's Health Insurance Program (``CHIP''), and...

  9. A simple clockless Network-on-Chip for a commercial audio DSP chip

    DEFF Research Database (Denmark)

    Stensgaard, Mikkel Bystrup; Bjerregaard, Tobias; Sparsø, Jens;

    2006-01-01

    We design a very small, packet-switched, clockless Network-on-Chip (NoC) as a replacement for the existing crossbar-based communication infrastructure in a commercial audio DSP chip. Both solutions are laid out in a 0.18 um process, and compared in terms of area, power consumption and routing...... complexity. Even though the NoC turns out to be larger and more power consuming than the existing crossbar implementation, it still accounts for less than 1% of the total chip area and power consumption, and is justified by a long list of advantages: The NoC is modular, scalable, and in contrast...

  10. CHIPS Neutrino Detector Research and Development

    Science.gov (United States)

    Salazar, Ramon; Vahle, Patricia; Chips Collaboration

    2015-04-01

    The CHIPS R&D project is an effort to develop affordable megaton-scale neutrino detectors. The CHIPS strategy calls for submerging water Cherenkov detectors deep under water. The surrounding water acts as structural support, minimizing large initial investments in costly infrastructure, and serves as an overburden, shielding the detector from cosmic rays and eliminating the need for expensive underground construction. Additional cost savings will be achieved through photodetector development and optimization of readout geometry. In summer 2014 a small prototype of the CHIPS detector was deployed in the flooded Wentworth Mine Pit in Northern Minnesota. The detector has been recording data underwater throughout the fall and winter. In this talk, we will discuss lessons learned from the prototyping experience and the plans for submerging much larger detectors in future years.

  11. A compact PE memory for vision chips

    Science.gov (United States)

    Cong, Shi; Zhe, Chen; Jie, Yang; Nanjian, Wu; Zhihua, Wang

    2014-09-01

    This paper presents a novel compact memory in the processing element (PE) for single-instruction multiple-data (SIMD) vision chips. The PE memory is constructed with 8 × 8 register cells, where one latch in the slave stage is shared by eight latches in the master stage. The memory supports simultaneous read and write on the same address in one clock cycle. Its compact area of 14.33 μm2/bit promises a higher integration level of the processor. A prototype chip with a 64 × 64 PE array is fabricated in a UMC 0.18 μm CMOS technology. Five types of the PE memory cell structure are designed and compared. The testing results demonstrate that the proposed PE memory architecture well satisfies the requirement of the vision chip in high-speed real-time vision applications, such as 1000 fps edge extraction.

  12. CHIPS: The Cosmological HI Power Spectrum Estimator

    CERN Document Server

    Trott, Cathryn M; Procopio, Pietro; Wayth, Randall B; Mitchell, Daniel A; McKinley, Benjamin; Tingay, Steven J; Barry, N; Beardsley, A P; Bernardi, G; Bowman, Judd D; Briggs, F; Cappallo, R J; Carroll, P; de Oliveira-Costa, A; Dillon, Joshua S; Ewall-Wice, A; Feng, L; Greenhill, L J; Hazelton, B J; Hewitt, J N; Hurley-Walker, N; Johnston-Hollitt, M; Jacobs, Daniel C; Kaplan, D L; Kim, HS; Lenc, E; Line, J; Loeb, A; Lonsdale, C J; Morales, M F; Morgan, E; Neben, A R; Thyagarajan, Nithyanandan; Oberoi, D; Offringa, A R; Ord, S M; Paul, S; Pober, J C; Prabu, T; Riding, J; Shankar, N Udaya; Sethi, Shiv K; Srivani, K S; Subrahmanyan, R; Sullivan, I S; Tegmark, M; Webster, R L; Williams, A; Williams, C L; Wu, C; Wyithe, J S B

    2016-01-01

    Detection of the cosmological neutral hydrogen signal from the Epoch of Reionization, and estimation of its basic physical parameters, is the principal scientific aim of many current low-frequency radio telescopes. Here we describe the Cosmological HI Power Spectrum Estimator (CHIPS), an algorithm developed and implemented with data from the Murchison Widefield Array (MWA), to compute the two-dimensional and spherically-averaged power spectrum of brightness temperature fluctuations. The principal motivations for CHIPS are the application of realistic instrumental and foreground models to form the optimal estimator, thereby maximising the likelihood of unbiased signal estimation, and allowing a full covariant understanding of the outputs. CHIPS employs an inverse-covariance weighting of the data through the maximum likelihood estimator, thereby allowing use of the full parameter space for signal estimation ("foreground suppression"). We describe the motivation for the algorithm, implementation, application to ...

  13. Variation Tolerant On-Chip Interconnects

    CERN Document Server

    Nigussie, Ethiopia Enideg

    2012-01-01

    This book presents design techniques, analysis and implementation of high performance and power efficient, variation tolerant on-chip interconnects.  Given the design paradigm shift to multi-core, interconnect-centric designs and the increase in sources of variability and their impact in sub-100nm technologies, this book will be an invaluable reference for anyone concerned with the design of next generation, high-performance electronics systems. Provides comprehensive, circuit-level explanation of high-performance, energy-efficient, variation-tolerant on-chip interconnect; Describes design techniques to mitigate problems caused by variation; Includes techniques for design and implementation of self-timed on-chip interconnect, delay variation insensitive communication protocols, high speed signaling techniques and circuits, bit-width independent completion detection and process, voltage and temperature variation tolerance.                          

  14. Rehydration characteristics and modeling of cassava chips

    Directory of Open Access Journals (Sweden)

    Ajala, A.S

    2015-05-01

    Full Text Available Cassava chips with dimension 4x2x0.2cm were re-hydrated in distilled water at 200C, 300C and 400C in a laboratory water bath. Kinetics of re-hydration was investigated using three different re-hydration models namely Peleg, exponential and Weibull. The pattern of water absorption was observed to be faster at the initial period of soaking. Higher temperature induces faster moisture absorption in the chips. Non linear regression analysis was used to fit in the experimental data and the coefficient of determination was found to be greater than 0.72 for all the models. The values of R2 , RMSE, MBE and reduced chi square showed that Weibull model best described the re-hydrating behaviour of the cassava chips.

  15. Performance Analysis and Comparison of Full Chip and Half Chip Rate DC and NC Code Acquisition in MIMO DSCDMA over Uncorrelated Rayleigh Wireless Channel

    OpenAIRE

    Kumar, N. Sathish; K.R. Shankar Kumar

    2011-01-01

    This paper presents the performance analysis and comparison of full chip and half chip rate of noncoherent (NC) and differentially coherent (DC) code acquisition scheme in (multiple input-multiple output) MIMO assisted by direct sequence spread spectrum (DS-CDMA) wireless system when communicated over uncorrelated Rayleigh channel. Four schemes are investigated, namely, SISO with full chip rate, SISO with Half chip rate, MIMO with full chip rate, and MIMO with half chip rate by varying the co...

  16. Lab-on a-Chip

    Science.gov (United States)

    1999-01-01

    Labs on chips are manufactured in many shapes and sizes and can be used for numerous applications, from medical tests to water quality monitoring to detecting the signatures of life on other planets. The eight holes on this chip are actually ports that can be filled with fluids or chemicals. Tiny valves control the chemical processes by mixing fluids that move in the tiny channels that look like lines, connecting the ports. Scientists at NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama designed this chip to grow biological crystals on the International Space Station (ISS). Through this research, they discovered that this technology is ideally suited for solving the challenges of the Vision for Space Exploration. For example, thousands of chips the size of dimes could be loaded on a Martian rover looking for biosignatures of past or present life. Other types of chips could be placed in handheld devices used to monitor microbes in water or to quickly conduct medical tests on astronauts. The portable, handheld Lab-on-a Chip Application Development Portable Test System (LOCAD-PTS) made its debut flight aboard Discovery during the STS-116 mission launched December 9, 2006. The system allowed crew members to monitor their environment for problematic contaminants such as yeast, mold, and even E.coli, and salmonella. Once LOCAD-PTS reached the ISS, the Marshall team continued to manage the experiment, monitoring the study from a console in the Payload Operations Center at MSFC. The results of these studies will help NASA researchers refine the technology for future Moon and Mars missions. (NASA/MSFC/D.Stoffer)

  17. Biostability of an implantable glucose sensor chip

    Science.gov (United States)

    Fröhlich, M.; Birkholz, M.; Ehwald, K. E.; Kulse, P.; Fursenko, O.; Katzer, J.

    2012-12-01

    Surface materials of an implantable microelectronic chip intended for medical applications were evaluated with respect to their long-term stability in bio-environments. The sensor chip shall apply in a glucose monitor by operating as a microviscosimeter according to the principle of affinity viscosimetry. A monolithic integration of a microelectromechanical system (MEMS) into the sensor chip was successfully performed in a combined 0.25 μm CMOS/BiCMOS technology. In order to study material durability and biostability of the surfaces, sensor chips were exposed to various in vitro and in vivo tests. Corrosional damage of SiON, SiO2 and TiN surfaces was investigated by optical microscopy, ellipsometry and AFM. The results served for optimizing the Back-end-of-Line (BEoL) stack, from which the MEMS was prepared. Corrosion of metal lines could significantly be reduced by improving the topmost passivation layer. The experiments revealed no visible damage of the actuator or other functionally important MEMS elements. Sensor chips were also exposed to human body fluid for three month by implantation into the abdomen of a volunteer. Only small effects were observed for layer thickness and Ra roughness after explantation. In particular, TiN as used for the actuator beam showed no degradation by biocorrosion. The highest degradation rate of about 50 nm per month was revealed for the SiON passivation layer. These results suggest that the sensor chip may safely operate in subcutaneous tissue for a period of several months.

  18. Integrated magneto-optical traps on a chip

    OpenAIRE

    Pollock, S.; Cotter, J. P.; Laliotis, A.; Hinds, E. A.

    2009-01-01

    We have integrated magneto-optical traps (MOTs) into an atom chip by etching pyramids into a silicon wafer. These have been used to trap atoms on the chip, directly from a room temperature vapor of rubidium. This new atom trapping method provides a simple way to integrate several atom sources on the same chip. It represents a substantial advance in atom chip technology and offers new possibilities for atom chip applications such as integrated single atom or photon sources and molecules on a c...

  19. A Neuron- and a Synapse Chip for Artificial Neural Networks

    OpenAIRE

    Lansner, John; Lehmann, Torsten

    1992-01-01

    A cascadable, analog, CMOS chip set has been developed for hardware implementations of artificial neural networks (ANN's):I) a neuron chip containing an array of neurons with hyperbolic tangent activation functions and adjustable gains, and II) a synapse chip (or a matrix-vector multiplier) where the matrix is stored on-chip as differential voltages on capacitors. In principal any ANN configuration can be made using these chips. A neuron array of 4 neurons and a 4 × 4 matrix-vector multiplie...

  20. CHIP: A new modulator of human malignant disorders

    Science.gov (United States)

    Shao, Qianqian; Yang, Gang; Zheng, Lianfang; Zhang, Taiping; Zhao, Yupei

    2016-01-01

    Carboxyl terminus of Hsc70-interacting protein (CHIP) is known as a chaperone-associated E3 for a variety of protein substrates. It acts as a link between molecular chaperones and ubiquitin–proteasome system. Involved in the process of protein clearance, CHIP plays a critical role in maintaining protein homeostasis in diverse conditions. Here, we provide a comprehensive review of our current understanding of CHIP and summarize recent advances in CHIP biology, with a focus on CHIP in the setting of malignancies. PMID:27007160

  1. An automatic system for elaboration of chip breaking diagrams

    DEFF Research Database (Denmark)

    Andreasen, Jan Lasson; De Chiffre, Leonardo

    1998-01-01

    A laboratory system for fully automatic elaboration of chip breaking diagrams has been developed and tested. The system is based on automatic chip breaking detection by frequency analysis of cutting forces in connection with programming of a CNC-lathe to scan different feeds, speeds and cutting...... depths. An evaluation of the system based on a total of 1671 experiments has shown that unfavourable snarled chips can be detected with 98% certainty which indeed makes the system a valuable tool in chip breakability tests. Using the system, chip breaking diagrams can be elaborated with a previously...

  2. CHIP: A new modulator of human malignant disorders.

    Science.gov (United States)

    Cao, Zhe; Li, Guanqiao; Shao, Qianqian; Yang, Gang; Zheng, Lianfang; Zhang, Taiping; Zhao, Yupei

    2016-05-17

    Carboxyl terminus of Hsc70-interacting protein (CHIP) is known as a chaperone-associated E3 for a variety of protein substrates. It acts as a link between molecular chaperones and ubiquitin-proteasome system. Involved in the process of protein clearance, CHIP plays a critical role in maintaining protein homeostasis in diverse conditions. Here, we provide a comprehensive review of our current understanding of CHIP and summarize recent advances in CHIP biology, with a focus on CHIP in the setting of malignancies.

  3. On-chip antenna: Practical design and characterization considerations

    KAUST Repository

    Shamim, Atif

    2012-07-28

    This paper highlights the challenges of an emergent field, namely, on-chip antenna design. Consistent with the RF System-on-Chip (SoC) concept, co-design strategy for circuits and on-chip antennas is described. A number of design and layout issues, arising from the highly integrated nature of this kind of systems, are discussed. The characterization difficulties related to on-chip antennas radiation properties are also highlighted. Finally, a novel on-wafer test fixture is proposed to measure the gain and radiation pattern of the on-chip antennas in the anechoic chamber.

  4. Microfluidic chip-capillary electrophoresis devices

    CERN Document Server

    Fung, Ying Sing; Du, Fuying; Guo, Wenpeng; Ma, Tongmei; Nie, Zhou; Sun, Hui; Wu, Ruige; Zhao, Wenfeng

    2015-01-01

    Capillary electrophoresis (CE) and microfluidic chip (MC) devices are relatively mature technologies, but this book demonstrates how they can be integrated into a single, revolutionary device that can provide on-site analysis of samples when laboratory services are unavailable. By introducing the combination of CE and MC technology, Microfluidic Chip-Capillary Electrophoresis Devices broadens the scope of chemical analysis, particularly in the biomedical, food, and environmental sciences.The book gives an overview of the development of MC and CE technology as well as technology that now allows

  5. Asynchronous design of Networks-on-Chip

    DEFF Research Database (Denmark)

    Sparsø, Jens

    2007-01-01

    The Network-on-chip concept has evolved as a solution to a broad range of problems related to the design of complex systems-on-chip (SoC) with tenths or hundreds of (heterogeneous) IP-cores. The paper introduces the NoC concept, identifies a range of possible timing organizations (globally......-synchronous, mesochronous, globally-asynchronous locally-synchronous and fully asynchronous), discusses the circuitry needed to implement these timing methodologies, and provides some implementation details for a couple of asynchronous NoCs designed at the Technical University of Denmark (DTU). The paper is written...

  6. Wireless Interconnect for Board and Chip Level

    OpenAIRE

    Fettweis, Gerhard P.; ul Hassan, Najeeb; Landau, Lukas; Fischer, Erik

    2013-01-01

    Electronic systems of the future require a very high bandwidth communications infrastructure within the system. This way the massive amount of compute power which will be available can be inter-connected to realize future powerful advanced electronic systems. Today, electronic inter-connects between 3D chip-stacks, as well as intra-connects within 3D chip-stacks are approaching data rates of 100 Gbit/s soon. Hence, the question to be answered is how to efficiently design the communications in...

  7. On-chip mode division multiplexing technologies

    DEFF Research Database (Denmark)

    Ding, Yunhong; Frellsen, Louise Floor; Guan, Xiaowei;

    2016-01-01

    Space division multiplexing (SDM) is currently widely investigated in order to provide enhanced capacity thanks to the utilization of space as a new degree of multiplexing freedom in both optical fiber communication and on-chip interconnects. Basic components allowing the processing of spatial...... using one-dimensional (1D) photonic crystal silicon waveguides. We furthermore use the fabricated devices to demonstrate on-chip point-to-point mode division multiplexing transmission, and all-optical signal processing by mode-selective wavelength conversion. Finally, we report an efficient silicon...

  8. Novel PbS detector chip pattern with extinction function

    Science.gov (United States)

    Chen, Fengjin; Si, Junjie; Su, Xianjun; Lv, Yanqiu; Shi, Zhengfeng

    2015-10-01

    A novel chip pattern with extinction function in Lead salt detectors is specified. Lead Sulfide (PbS) polycrystalline film is prepared by Chemical Bath Deposition (CMD) on a transparent substrate, then a special figure and structure is saved by lithography techonology on the substrate. As a quaternion detector chip that made by PbS thin film for example in this paper, whose performance including signal, noise, weak-peaks and the uniformity of the chip are too poor to meet the detecting system at the initial stage of research, and the qualified ratio of chips is only 3% .This paper explains the reason why the performance and qualified ratio of chips were so poor, focuses on a novel chip pattern with extinction which avoided the disadvantages of traditional one. the novel chip pattern has been applied in detectors. The novel chip pattern is prepared with PbS thin film which both "extinction slice" and detector chip are based on a same substrate , which not only had absorbed the jumbled light , improved the uniformity and other performance of photosensitive elements, but also had left out the assembly diffculty and precision demand when a extinction slice assembly in the restricted space of inswept detector chip, omitted the production process of extinction slice and shorten the assembly process of the detectors, and the qualified ratio of chips had been improved from 3% to 98%.

  9. Investigation of formation mechanisms of chips in orthogonal cutting process

    Science.gov (United States)

    Ma, W.

    2012-08-01

    This work investigates the formation mechanisms of chips in orthogonal cutting of mild steel and the transformation conditions between various morphology chips. It is supposed that the modeling material follows the Johnson-Cook constitutive model. In orthogonal cutting process, both the plastic flow and the instability behaviors of chip materials are caused by the plane strain loadings. Therefore, the general instability behaviors of materials in plane strain state are first analyzed with linear perturbation method and a universal instability criterion is established. Based on the analytical results, the formation mechanisms of chips and the transformation conditions between continuous and serrated chips are further studied by instability phase diagram method. The results show that the chip formation strongly depends on the intensity ratios between shear and normal stresses. The ratios of dissipative rates of plastic work done by compression and shear stresses govern the transformation from continuous to serrated chips. These results are verified by the numerical simulations on the orthogonal cutting process.

  10. The Distributed Network Processor: a novel off-chip and on-chip interconnection network architecture

    CERN Document Server

    Biagioni, Andrea; Lonardo, Alessandro; Paolucci, Pier Stanislao; Perra, Mersia; Rossetti, Davide; Sidore, Carlo; Simula, Francesco; Tosoratto, Laura; Vicini, Piero

    2012-01-01

    One of the most demanding challenges for the designers of parallel computing architectures is to deliver an efficient network infrastructure providing low latency, high bandwidth communications while preserving scalability. Besides off-chip communications between processors, recent multi-tile (i.e. multi-core) architectures face the challenge for an efficient on-chip interconnection network between processor's tiles. In this paper, we present a configurable and scalable architecture, based on our Distributed Network Processor (DNP) IP Library, targeting systems ranging from single MPSoCs to massive HPC platforms. The DNP provides inter-tile services for both on-chip and off-chip communications with a uniform RDMA style API, over a multi-dimensional direct network with a (possibly) hybrid topology.

  11. Cool down computer chips with liquid metal device driven by the heat of chips

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ With the soaring advances in computational speed, thermal management becomes a major concern in computer systems. To remove heat generated by computer chips or very large scale integrated circuits, a research team headed by Prof.

  12. An analog CMOS chip set for neural networks with arbitrary topologies

    DEFF Research Database (Denmark)

    Lansner, John; Lehmann, Torsten

    1993-01-01

    An analog CMOS chip set for implementations of artificial neural networks (ANNs) has been fabricated and tested. The chip set consists of two cascadable chips: a neuron chip and a synapse chip. Neurons on the neuron chips can be interconnected at random via synapses on the synapse chips thus...... implementing an ANN with arbitrary topology. The neuron test chip contains an array of 4 neurons with well defined hyperbolic tangent activation functions which is implemented by using parasitic lateral bipolar transistors. The synapse test chip is a cascadable 4×4 matrix-vector multiplier with variable, 10-b...

  13. The Distributed Network Processor: a novel off-chip and on-chip interconnection network architecture

    OpenAIRE

    Biagioni, Andrea; Cicero, Francesca Lo; Lonardo, Alessandro; Paolucci, Pier Stanislao; Perra, Mersia; Rossetti, Davide; Sidore, Carlo; Simula, Francesco; Tosoratto, Laura; Vicini, Piero

    2012-01-01

    One of the most demanding challenges for the designers of parallel computing architectures is to deliver an efficient network infrastructure providing low latency, high bandwidth communications while preserving scalability. Besides off-chip communications between processors, recent multi-tile (i.e. multi-core) architectures face the challenge for an efficient on-chip interconnection network between processor's tiles. In this paper, we present a configurable and scalable architecture, based on...

  14. "Hook"-calibration of GeneChip-microarrays: Chip characteristics and expression measures

    Directory of Open Access Journals (Sweden)

    Krohn Knut

    2008-08-01

    Full Text Available Abstract Background Microarray experiments rely on several critical steps that may introduce biases and uncertainty in downstream analyses. These steps include mRNA sample extraction, amplification and labelling, hybridization, and scanning causing chip-specific systematic variations on the raw intensity level. Also the chosen array-type and the up-to-dateness of the genomic information probed on the chip affect the quality of the expression measures. In the accompanying publication we presented theory and algorithm of the so-called hook method which aims at correcting expression data for systematic biases using a series of new chip characteristics. Results In this publication we summarize the essential chip characteristics provided by this method, analyze special benchmark experiments to estimate transcript related expression measures and illustrate the potency of the method to detect and to quantify the quality of a particular hybridization. It is shown that our single-chip approach provides expression measures responding linearly on changes of the transcript concentration over three orders of magnitude. In addition, the method calculates a detection call judging the relation between the signal and the detection limit of the particular measurement. The performance of the method in the context of different chip generations and probe set assignments is illustrated. The hook method characterizes the RNA-quality in terms of the 3'/5'-amplification bias and the sample-specific calling rate. We show that the proper judgement of these effects requires the disentanglement of non-specific and specific hybridization which, otherwise, can lead to misinterpretations of expression changes. The consequences of modifying probe/target interactions by either changing the labelling protocol or by substituting RNA by DNA targets are demonstrated. Conclusion The single-chip based hook-method provides accurate expression estimates and chip-summary characteristics

  15. Quality requirements for forest chips; Kaeyttaejien laatuvaatimukset metsaehakkeelle

    Energy Technology Data Exchange (ETDEWEB)

    Impola, R. [VTT Energy, Jyvaeskylae (Finland)

    1999-07-01

    Forest chips have been used decades in Finland for energy purposes. Increment of oil prices has periodically increased the construction of municipal district heating plants. The utilization of forest chips in 1998 for energy was 0.5 million m{sup 3} (1.2 million bulk-m{sup 3}). The objective of the National Wood Energy Research Program is to increase the annual consumption of forest chips up to 2.5 million m{sup 3} (about 5 TWh) within 5 years. The largest additional potential for forest chips is in mixed combustion of forest chips in large energy production plants (e.g. power plants of forest industry). In smaller target (district heating plants and heating of large real estates) the regional significance of the utilization of forest chips is often significant. Logging residues from final fellings of spruce predominant felling areas form the largest and most profitable potential source of forest chips. Other interesting targets for the future are harvesting of energy wood from silvicultural plantations and first thinnings of lots. In present power plants there are not such technical solutions in use, which would prevent the enhancement of the utilization of forest chip, especially if chips to be combusted are mixed e.g. with peat. Even though the fuel processing systems are designed for processing of peat, bark and wood residues, the utilization of pure forest chip might cause problems, e.g. freezing of moist forest chips and arching in the reception, conveyors and storage. Problems might occur also in sieving and crushing of chips. The quality of forest chips plays an important role. The moisture content has to be in control also in winter. The homogeneity of chips, including the particle size, has to be suitable for the plants. Oversized particles, long branches and impurities cause problems in processing and feeding devices. Secure purchase and reliable delivery of the fuel under all circumstances are the main factors effecting on the increment of the

  16. On-chip concentration of bacteria using a 3D dielectrophoretic chip and subsequent laser-based DNA extraction in the same chip

    International Nuclear Information System (INIS)

    We report the on-chip concentration of bacteria using a dielectrophoretic (DEP) chip with 3D electrodes and subsequent laser-based DNA extraction in the same chip. The DEP chip has a set of interdigitated Au post electrodes with 50 µm height to generate a network of non-uniform electric fields for the efficient trapping by DEP. The metal post array was fabricated by photolithography and subsequent Ni and Au electroplating. Three model bacteria samples (Escherichia coli, Staphylococcus epidermidis, Streptococcus mutans) were tested and over 80-fold concentrations were achieved within 2 min. Subsequently, on-chip DNA extraction from the concentrated bacteria in the 3D DEP chip was performed by laser irradiation using the laser-irradiated magnetic bead system (LIMBS) in the same chip. The extracted DNA was analyzed with silicon chip-based real-time polymerase chain reaction (PCR). The total process of on-chip bacteria concentration and the subsequent DNA extraction can be completed within 10 min including the manual operation time.

  17. Sensing systems using chip-based spectrometers

    Science.gov (United States)

    Nitkowski, Arthur; Preston, Kyle J.; Sherwood-Droz, Nicolás.; Behr, Bradford B.; Bismilla, Yusuf; Cenko, Andrew T.; DesRoches, Brandon; Meade, Jeffrey T.; Munro, Elizabeth A.; Slaa, Jared; Schmidt, Bradley S.; Hajian, Arsen R.

    2014-06-01

    Tornado Spectral Systems has developed a new chip-based spectrometer called OCTANE, the Optical Coherence Tomography Advanced Nanophotonic Engine, built using a planar lightwave circuit with integrated waveguides fabricated on a silicon wafer. While designed for spectral domain optical coherence tomography (SD-OCT) systems, the same miniaturized technology can be applied to many other spectroscopic applications. The field of integrated optics enables the design of complex optical systems which are monolithically integrated on silicon chips. The form factors of these systems can be significantly smaller, more robust and less expensive than their equivalent free-space counterparts. Fabrication techniques and material systems developed for microelectronics have previously been adapted for integrated optics in the telecom industry, where millions of chip-based components are used to power the optical backbone of the internet. We have further adapted the photonic technology platform for spectroscopy applications, allowing unheard-of economies of scale for these types of optical devices. Instead of changing lenses and aligning systems, these devices are accurately designed programmatically and are easily customized for specific applications. Spectrometers using integrated optics have large advantages in systems where size, robustness and cost matter: field-deployable devices, UAVs, UUVs, satellites, handheld scanning and more. We will discuss the performance characteristics of our chip-based spectrometers and the type of spectral sensing applications enabled by this technology.

  18. Smart Chips for Smart Surroundings - 4S

    NARCIS (Netherlands)

    Schuler, Eberhard; König, Ralf; Becker, Jürgen; Rauwerda, Gerard; Burgwal, van de Marcel; Smit, Gerard J.M.; Cardoso, João M.P.; Hübner, Michael

    2011-01-01

    The overall mission of the 4S project (Smart Chips for Smart Surroundings) was to define and develop efficient flexible, reconfigurable core building blocks, including the supporting tools, for future Ambient System Devices. Reconfigurability offers the needed flexibility and adaptability, it provid

  19. Hybrid photonic chip interferometer for embedded metrology

    Science.gov (United States)

    Kumar, P.; Martin, H.; Maxwell, G.; Jiang, X.

    2014-03-01

    Embedded metrology is the provision of metrology on the manufacturing platform, enabling measurement without the removal of the work piece. Providing closer integration of metrology upon the manufacturing platform can lead to the better control and increased throughput. In this work we present the development of a high precision hybrid optical chip interferometer metrology device. The complete metrology sensor system is structured into two parts; optical chip and optical probe. The hybrid optical chip interferometer is based on a silica-on-silicon etched integrated-optic motherboard containing waveguide structures and evanescent couplers. Upon the motherboard, electro-optic components such as photodiodes and a semiconductor gain block are mounted and bonded to provide the required functionality. The key structure in the device is a tunable laser module based upon an external-cavity diode laser (ECDL). Within the cavity is a multi-layer thin film filter which is rotated to select the longitudinal mode at which the laser operates. An optical probe, which uses a blazed diffracting grating and collimating objective lens, focuses light of different wavelengths laterally over the measurand. Incident laser light is then tuned in wavelength time to effectively sweep an `optical stylus' over the surface. Wavelength scanning and rapid phase shifting can then retrieve the path length change and thus the surface height. We give an overview of the overall design of the final hybrid photonic chip interferometer, constituent components, device integration and packaging as well as experimental test results from the current version now under evaluation.

  20. DEHYDRATION AND DEOILING OF METAL CHIP

    Directory of Open Access Journals (Sweden)

    O. M. Djakonov

    2011-01-01

    Full Text Available Influence of technology factors on efficiency of processes of dehydration and deoiling of metal chips is investigated. The new universal simple method of definition of coefficients of filtration and free infiltration of liquid in porous medium is offered.

  1. Microprocessors: From basic chips to complete systems

    International Nuclear Information System (INIS)

    These lectures aim to present and explain in general terms some of the characteristics of microprocessor chips and associated components. They show how systems are synthesized from the basic integrated circuit building blocks which are currently available; processor, memory, input-output (I/0) devices, etc. (orig./HSI)

  2. A multipurpose programmable read-out chip

    International Nuclear Information System (INIS)

    A mixed-signal integrated chip in IBM 130nm technology suitable to a variety of detectors with different requirements is under development. The CBM experiment at FAIR could be a good candidate for the use of this chip. The chip can read out 128 channels, which can be masked in groups of 16, 32 or 64. The multichannel ASIC includes a low noise PreAmplifier and Shaping Amplifier (PASA), a Peak Detector (PD), a Time-to-Amplitude Converter (TAC) and fast arbitration and sequencing logic to concentrate the data before it is sent to a pipelined Analog-to-Digital Converter (ADC). The chip is self-triggered, which is essential for applications where the detector pulses arrive randomly in time. The PASA is programmable for different detector capacitances (from 1 pF to 50 pF), input pulse polarity, preamplifier gain, peaking time (from 20 to 200 ns) and conversion gain in order to suit a wide range of application requirements. The ADC is programmable to support either 8, 10 or 12 bit resolution with a conversion rate from 1 MHz to 100 MHz; the switched-capacitor bias network provides bias currents proportional to the operating frequency. Simulations of the ADC will be shown together with plots of the expected performance

  3. Drying characteristics of willow chips and stems

    NARCIS (Netherlands)

    Gigler, J.K.; Loon, van W.K.P.; Seres, I.; Meerdink, G.; Coumans, W.J.

    2000-01-01

    In supply chains of willow (Salix viminalis) biomass to energy plants, drying is advisable in order to enable safe long-term storage, increase boiler efficiency and reduce gaseous emissions. To gain insight into the drying process, drying characteristics of willow chips and stems were investigated e

  4. Writing for a Change, Writing for Chip

    Science.gov (United States)

    Berry, Patrick W.

    2014-01-01

    What does it mean to write for change? How do we negotiate the space between hope and critique? Drawing on Dewey's notion of a common faith, this article contemplates what the author learned from Chip Bruce. It suggests that when we compartmentalize the ideal and the everyday, the hopeful and the critical, we reduce the complexity of human…

  5. Production Quality Control Of Microfluidic Chip Designs

    DEFF Research Database (Denmark)

    Calaon, Matteo; Hansen, Hans Nørgaard; Tosello, Guido;

    2012-01-01

    environment the precision of measuring results and the accuracy of measurement relocation are very relevant. In this paper, the possibility of producing with high volume Lab-on-chip devices through injection molding are presented. Preparation of master geometries was made by etching a Si wafer by e...

  6. Increasing security in inter-chip communication

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, Nathan J; Hamlet, Jason; Bauer, Todd; Helinski, Ryan

    2014-10-28

    An apparatus for increasing security in inter-chip communication includes a sending control module, a communication bus, and a receiving control module. The communication bus is coupled between the sending control module and the receiving control module. The sending control module operates to send data on the communication bus, disable the communication bus when threats are detected, or both.

  7. What's A Pixel Particle Sensor Chip?

    CERN Multimedia

    2008-01-01

    ATLAS particle physics experiment aided with collaboration ON Semiconductor was recently honored by the European Council for Nuclear Research (CERN), with an Industrial Award recognizing the company's contribution in supplying complex "Pixel Particle Sensor" chips for use in CERN's ATLAS particle physics experiment.

  8. PLC Multi-Chip Integration Technologies

    Institute of Scientific and Technical Information of China (English)

    Motohaya; Ishii

    2003-01-01

    This paper reviews recent progress on integrated multi-chip modules composed of silica-based planar lightwave circuits (PLCs) with a relatively high core-to-cladding index contrast A. These compact and highly functional modules were fabricated by using the PLC-PLC direct attachment technique.

  9. PLC Multi-Chip Integration Technologies

    Institute of Scientific and Technical Information of China (English)

    Motohaya Ishii

    2003-01-01

    This paper reviews recent progress on integrated multi-chip modules composed of silica-based planarlightwave circuits (PLCs) with a relatively high core-to-cladding index contrast △. These compact and highlyfunctional modules were fabricated by using the PLC-PLC direct attachment technique.

  10. The Kindness in a Bag of Chips

    Institute of Scientific and Technical Information of China (English)

    韩小庆

    2011-01-01

    Last Sunday, my son and I were in line at the Dollar store buying an assortment of products. In a line next to ours, a woman was waiting to make her 1 . She had a few necessities and one bag of chips.

  11. The Kindness in a Bag of Chips

    Institute of Scientific and Technical Information of China (English)

    韩小庆

    2011-01-01

    难度:★★★☆☆词数:406建议阅读时间:10分钟Last Sunday, my son and I were in line at the Dollar store buying an assortment of products. In a line next to ours, a woman was waiting to make her 1 . She had a few necessities and one bag of chips.

  12. Light-colored, Low Acrylamide Potato Chips

    Science.gov (United States)

    Potato tubers are stored at cold temperatures to prevent sprouting, minimize disease losses and increase the marketing window. Cold storage also causes an accumulation of reducing sugars, a phenomenon referred to as cold-induced sweetening. Unacceptable, dark colored chips and fries are formed durin...

  13. The V-Chip--Victory or Vendetta?

    Science.gov (United States)

    Payne, Ron

    1997-01-01

    Parents can install the v-chip microchip in their televisions to block out programs high in violence, sex, or other objectional material. Examines the views of supporters, who see it as a coping tool for the information age and of detractors who see it as an affront to the First Amendment guarantee of free speech. (SM)

  14. 76 FR 79215 - Certain Semiconductor Chips With Dram Circuitry, and Modules and Products Containing Same...

    Science.gov (United States)

    2011-12-21

    ... COMMISSION Certain Semiconductor Chips With Dram Circuitry, and Modules and Products Containing Same... importation of certain semiconductor chips with DRAM circuitry, and modules and products containing same by... after importation of certain semiconductor chips with DRAM circuitry, and modules and...

  15. Neural network chips for trigger purposes in high energy physics

    International Nuclear Information System (INIS)

    Two novel neural chips SAND (Simple Applicable Neural Device) and SIOP (Serial Input - Operating Parallel) are described. Both are highly usable for hardware triggers in particle physics. The chips are optimized for a high input data rate at a very low cost basis. The performance of a single SAND chip is 200 MOPS due to four parallel 16 bit multipliers and 40 bit adders working in one clock cycle. The chip is able to implement feedforward neural networks, Kohonen feature maps and radial basis function networks. Four chips will be implemented on a PCI-board for simulation and on a VUE board for trigger and on- and off-line analysis. For small sized feedforward neural networks the bit-serial neuro-chip SIOP may lead to even smaller latencies because each synaptic connection is implemented by its own bit serial multiplier and adder

  16. Atom chip based generation of entanglement for quantum metrology

    CERN Document Server

    Riedel, Max F; Li, Yun; Hänsch, Theodor W; Sinatra, Alice; Treutlein, Philipp

    2010-01-01

    Atom chips provide a versatile `quantum laboratory on a microchip' for experiments with ultracold atomic gases. They have been used in experiments on diverse topics such as low-dimensional quantum gases, cavity quantum electrodynamics, atom-surface interactions, and chip-based atomic clocks and interferometers. A severe limitation of atom chips, however, is that techniques to control atomic interactions and to generate entanglement have not been experimentally available so far. Such techniques enable chip-based studies of entangled many-body systems and are a key prerequisite for atom chip applications in quantum simulations, quantum information processing, and quantum metrology. Here we report experiments where we generate multi-particle entanglement on an atom chip by controlling elastic collisional interactions with a state-dependent potential. We employ this technique to generate spin-squeezed states of a two-component Bose-Einstein condensate and show that they are useful for quantum metrology. The obser...

  17. A fast template matching method for LED chip Localization

    Directory of Open Access Journals (Sweden)

    Zhong Fuqiang

    2015-01-01

    Full Text Available Efficiency determines the profits of the semiconductor producers. So the producers spare no effort to enhance the efficiency of every procedure. The purpose of the paper is to present a method to shorten the time to locate the LED chips on wafer. The method consists of 3 steps. Firstly, image segmentation and blob analyzation are used to predict the positions of potential chips. Then predict the orientations of potential chips based on their dominant orientations. Finally, according to the positions and orientations predicted above, locate the chips precisely based on gradient orientation features. Experiments show that the algorithm is faster than the traditional method we choose to locate the LED chips. Besides, even the orientations of the chips on wafer are of big deviation to the orientation of the template, the efficiency of this method won't be affected.

  18. Neural network chips for trigger purposes in high energy physics

    Energy Technology Data Exchange (ETDEWEB)

    Gemmeke, H.; Eppler, W.; Fischer, T. [Research Center Karlsruhe (Germany)] [and others

    1996-12-31

    Two novel neural chips SAND (Simple Applicable Neural Device) and SIOP (Serial Input - Operating Parallel) are described. Both are highly usable for hardware triggers in particle physics. The chips are optimized for a high input data rate at a very low cost basis. The performance of a single SAND chip is 200 MOPS due to four parallel 16 bit multipliers and 40 bit adders working in one clock cycle. The chip is able to implement feedforward neural networks, Kohonen feature maps and radial basis function networks. Four chips will be implemented on a PCI-board for simulation and on a VUE board for trigger and on- and off-line analysis. For small sized feedforward neural networks the bit-serial neuro-chip SIOP may lead to even smaller latencies because each synaptic connection is implemented by its own bit serial multiplier and adder.

  19. A primary battery-on-a-chip using monolayer graphene

    Science.gov (United States)

    Iost, Rodrigo M.; Crespilho, Frank N.; Kern, Klaus; Balasubramanian, Kannan

    2016-07-01

    We present here a bottom-up approach for realizing on-chip on-demand batteries starting out with chemical vapor deposition-grown graphene. Single graphene monolayers contacted by electrode lines on a silicon chip serve as electrodes. The anode and cathode are realized by electrodeposition of zinc and copper respectively onto graphene, leading to the realization of a miniature graphene-based Daniell cell on a chip. The electrolyte is housed partly in a gel and partly in liquid form in an on-chip enclosure molded using a 3d printer or made out of poly(dimethylsiloxane). The realized batteries provide a stable voltage (∼1.1 V) for many hours and exhibit capacities as high as 15 μAh, providing enough power to operate a pocket calculator. The realized batteries show promise for deployment as on-chip power sources for autonomous systems in lab-on-a-chip or biomedical applications.

  20. Application of Ferrite Nanomaterial in RF On-Chip Inductors

    Directory of Open Access Journals (Sweden)

    Hua-Lin Cai

    2013-01-01

    Full Text Available Several kinds of ferrite-integrated on-chip inductors are presented. Ferrite nanomaterial applied in RF on-chip inductors is prepared and analyzed to show the properties of high permeability, high ferromagnetic resonance frequency, high resistivity, and low loss, which has the potential that will improve the performance of RF on-chip inductors. Simulations of different coil and ferrite nanomaterial parameters, inductor structures, and surrounding structures are also conducted to achieve the trend of gains of inductance and quality factor of on-chip inductors. By integrating the prepared ferrite magnetic nanomaterial to the on-chip inductors with different structures, the measurement performances show an obvious improvement even in GHz frequency range. In addition, the studies of CMOS compatible process to integrate the nanomaterial promote the widespread application of magnetic nanomaterial in RF on-chip inductors.

  1. Flip-chip light emitting diode with resonant optical microcavity

    Science.gov (United States)

    Gee, James M.; Bogart, Katherine H.A.; Fischer, Arthur J.

    2005-11-29

    A flip-chip light emitting diode with enhanced efficiency. The device structure employs a microcavity structure in a flip-chip configuration. The microcavity enhances the light emission in vertical modes, which are readily extracted from the device. Most of the rest of the light is emitted into waveguided lateral modes. Flip-chip configuration is advantageous for light emitting diodes (LEDs) grown on dielectric substrates (e.g., gallium nitride LEDs grown on sapphire substrates) in general due to better thermal dissipation and lower series resistance. Flip-chip configuration is advantageous for microcavity LEDs in particular because (a) one of the reflectors is a high-reflectivity metal ohmic contact that is already part of the flip-chip configuration, and (b) current conduction is only required through a single distributed Bragg reflector. Some of the waveguided lateral modes can also be extracted with angled sidewalls used for the interdigitated contacts in the flip-chip configuration.

  2. Liquid-phase microextraction in a microfluidic-chip

    DEFF Research Database (Denmark)

    Payán, María D. Ramos; Jensen, Henrik; Petersen, Nickolaj J.;

    2012-01-01

    In this work, a microfluidic-chip based system for liquid-phase microextraction (LPME-chip) was developed. Sample solutions were pumped into the LPME-chip with a micro-syringe pump at a flow rate of 3-4µLmin(-1). Inside the LPME chip, the sample was in direct contact with a supported liquid...... electrophoresis for exact quantification, or on-line by UV detection or electrospray ionization mass spectrometry for time profiling of concentrations. The LPME-chip was found to be highly effective, and extraction efficiencies were in the range of 52-91%. When the flow of acceptor phase was turned off during...... that the LPME-chip has great potentials for very efficient analyte enrichments from limited sample volumes in the future....

  3. Photonic Wire Bonds for Terabit/s Chip-to-Chip Interconnects

    CERN Document Server

    Lindenmann, Nicole; Hillerkuss, David; Schmogrow, Rene; Jordan, Meinert; Leuthold, Juerg; Freude, Wolfgang; Koos, Christian

    2011-01-01

    Photonic integration has witnessed tremendous progress over the last years, and chip-scale transceiver systems with Terabit/s data rates have come into reach. However, as on-chip integration density increases, efficient off-chip interfaces are becoming more and more crucial. A technological breakthrough is considered indispensable to cope with the challenges arising from large-scale photonic integration, and this particularly applies to short-distance optical interconnects. In this letter we introduce the concept of photonic wire bonding, where transparent waveguide wire bonds are used to bridge the gap between nanophotonic circuits located on different chips. We demonstrate for the first time the fabrication of three-dimensional freeform photonic wire bonds (PWB), and we confirm their viability in a multi-Terabit/s data transmission experiment. First-generation prototypes allow for efficient broadband coupling with overall losses of only 1.6 dB. Photonic wire bonding will enable flexible optical multi-chip a...

  4. Exploring Alternative Topologies for Network-on-Chip Architectures

    OpenAIRE

    Shafi Patel; Parag Parandkar; Sumant Katiyal; Ankit Agrawal

    2011-01-01

    With increase in integration density and complexity of the system-on-Chip (SOC), the conventional interconnects are not suitable to fulfill the demands. The application of traditional network technologies in the form of Network-on-Chip is a potential solution. NoC design space has many variables. Selection of a better topology results in lesser complexities and better power-efficiency. In the proposed work, key research area in Network-on-chip design targeting communication infrastructure spe...

  5. Polystyrene Based SPR Biosensor Chip for Use in Immunoassay

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    Biosensors are widely used in immunoassay.The biosensor chip carries a receptor which is used in immunoassay and the chip properties have an important influence on the detecting sensitivity of the biosensor.This paper describes a polystyrene-based biosensor chip developed and used as part of a surface plasmon resonance (SPR) biosensor.The SPR biosensor has a much higher detecting sensitivity than enzyme-linked immunoserbent assay (ELISA).

  6. Wood chips procurement and research project at the Mikkeli region

    International Nuclear Information System (INIS)

    In 1993-94, a large-scale energywood production chain started as a co-operation project by the Mikkeli city forest office and local forestry societies. In 1995 over 115 000 m3 (about 85 000 MWh of energy) of wood chips were delivered to Pursiala heat and power plant in Mikkeli. About 75 % of these chips was forest processed chips. About 70 % of the forest processed chips was whole tree chips from improvement cuttings of young forest stands and the rest was logging waste chips from regeneration cutting areas. The average total delivery costs of forest processed chips after reduction of energywood and other subsidies were approximately 45 FIM/m3 (60 FIM/MWh) for the whole tree chips and 38 FIM/m3 (50 FIM/MWh) for logging waste chips. The delivery costs of forest processed chips could meet the target of Bioenergy Research Programme (45 FIM/MWh) only in the most favourable cases. In an average the delivery costs were about 9 FIM/MWh more than the price obtained when sold to the heat and power plant. However the wood chip production created 27 new jobs and the increase of income to the local economy was about 2.2 milj. FIM /year. The local communities got new tax revenue about 3 FIM/MWh. The gain for the forestry was approximated to be 5 - 6 FIM/MWh. The resources of forest processed chips were studied on the basis of stand measurements. According to the study the most remarkable energywood resources were in young thinning stands on Oxalis-Myrtillus and Myrtillus forest site types. On Oxalis-Myrtillus type almost every and on Myrtillus type every second stand included energywood more than 40 m3/ha

  7. Technology for melting amber chips to produce a solid block

    Science.gov (United States)

    Vikhareva, A. S.; Melnikov, A. G.; Utyev, O. M.

    2016-04-01

    This research is relevant, because the bulk of the mined amber comes in amber chips. Therefore, we have decided to review the current ways of melting amber chips to develop the most technologically efficient algorithm and to use it further for producing decorative items. The purpose of the work is to perfect the technology of obtaining whole-piece amber from amber chips and to explore the usability of the obtained material in decorative items and jewelry.

  8. CMOS Image Sensors: Electronic Camera On A Chip

    Science.gov (United States)

    Fossum, E. R.

    1995-01-01

    Recent advancements in CMOS image sensor technology are reviewed, including both passive pixel sensors and active pixel sensors. On- chip analog to digital converters and on-chip timing and control circuits permit realization of an electronic camera-on-a-chip. Highly miniaturized imaging systems based on CMOS image sensor technology are emerging as a competitor to charge-coupled devices for low cost uses.

  9. DFT Techniques in DSP Chip Core NDSP25

    Institute of Scientific and Technical Information of China (English)

    XUE Jing; BAI Yong-qiang; DENG Zheng-hong; ZHENG Wei

    2004-01-01

    Design for Testability(DFT) is critical in chip design.DFT techniques insert hardware logic to an original design,in order to improve testability of the chip,and thus reduce test cost significantly.In this paper,we introduces the most frequently used DFT techniques,then put emphasis on the DFT policy and the DFT realization of the NDSP25 chip core,and analyses the result at last.

  10. Large Chip Production Mechanism under the Extreme Load Cutting Conditions

    Institute of Scientific and Technical Information of China (English)

    LIU Xianli; HE Genghuang; YAN Fugang; CHENG Yaonan; LIU Li

    2015-01-01

    There has existed a great deal of theory researches in term of chip production and chip breaking characteristics under conventional cutting and high speed cutting conditions, however, there isn’t sufficient research on chip formation mechanism as well as its influence on cutting state regarding large workpieces under extreme load cutting. This paper presents a model of large saw-tooth chip through applying finite element simulation method, which gives a profound analysis about the characteristics of the extreme load cutting as well as morphology and removal of the large chip. In the meantime, a calculation formula that gives a quantitative description of the saw-tooth level regarding the large chip is established on the basis of cutting experiments on high temperature and high strength steel 2.25Cr-1Mo-0.25V. The cutting experiments are carried out by using the scanning electron microscope and super depth of field electron microscope to measure and calculate the large chip produced under different cutting parameters, which can verify the validity of the established model. The calculating results show that the large saw-toothed chip is produced under the squeezing action between workpiece and cutting tools. In the meanwhile, the chip develops a hardened layer where contacts the cutting tool and the saw-tooth of the chip tend to form in transverse direction. This research creates the theoretical model for large chip and performs the cutting experiments under the extreme load cutting condition, as well as analyzes the production mechanism of the large chip in the macro and micro conditions. Therefore, the proposed research could provide theoretical guidance and technical support in improving productivity and cutting technology research.

  11. Low-power chip-level optical interconnects based on bulk-silicon single-chip photonic transceivers

    Science.gov (United States)

    Kim, Gyungock; Park, Hyundai; Joo, Jiho; Jang, Ki-Seok; Kwack, Myung-Joon; Kim, Sanghoon; Kim, In Gyoo; Kim, Sun Ae; Oh, Jin Hyuk; Park, Jaegyu; Kim, Sanggi

    2016-03-01

    We present new scheme for chip-level photonic I/Os, based on monolithically integrated vertical photonic devices on bulk silicon, which increases the integration level of PICs to a complete photonic transceiver (TRx) including chip-level light source. A prototype of the single-chip photonic TRx based on a bulk silicon substrate demonstrated 20 Gb/s low power chip-level optical interconnects between fabricated chips, proving that this scheme can offer compact low-cost chip-level I/O solutions and have a significant impact on practical electronic-photonic integration in high performance computers (HPC), cpu-memory interface, 3D-IC, and LAN/SAN/data-center and network applications.

  12. Alignment of microcircuit chips using optically smeared images.

    Science.gov (United States)

    Lewis, R W

    1979-02-01

    An optical method for determining the position of microcircuit chips for wirebonding or electrical testing stations was evaluated. Optically smearing the chip image in one direction with a cylindrical lens produces a convenient means for determining both chip angular orientation and position. Digitized images from a linear photodiode array camera were analyzed. The results show that a class of microcircuit chips with medium scale integration can be aligned in angle and position to a higher accuracy than required for wirebonding and electrical testing stations. PMID:20208714

  13. Integrated lasers for polymer Lab-on-a-Chip systems

    DEFF Research Database (Denmark)

    Mappes, Timo; Vannahme, Christoph; Grosmann, Tobias;

    2012-01-01

    We develop optical Lab-on-a-Chips on different platforms for marker-based and label-free biophotonic sensor applications. Our chips are based on polymers and fabricated by mass production technologies to integrate microfluidic channels, optical waveguides and miniaturized lasers.......We develop optical Lab-on-a-Chips on different platforms for marker-based and label-free biophotonic sensor applications. Our chips are based on polymers and fabricated by mass production technologies to integrate microfluidic channels, optical waveguides and miniaturized lasers....

  14. HPV 9G DNA Chip: 100% Clinical Sensitivity and Specificity

    OpenAIRE

    An, Heejung; Song, Keum-Soo; Nimse, Satish Balasaheb; Kim, Junghoon; Nguyen, Van-Thuan; Ta, Van-Thao; Sayyed, Danishmalik Rafiq; Kim, Taisun

    2012-01-01

    We describe a novel HPV 9G DNA chip test for the accurate and reliable genotyping of human papillomavirus (HPV). The HPV 9G DNA chip test established its efficiency in terms of a signal-to-background ratio (SBR) of 200, which is 50 times superior to commercial HPV DNA chips, and 100% target-specific hybridization at 25°C. We compared the genotyping results for the 439 clinical samples by the HPV 9G DNA chip test with the sequencing results for the MY11/GP6+ (M2) primer set-mediated PCR produc...

  15. Numerical Simulation of Chip Formation in Metal Cutting Process

    Directory of Open Access Journals (Sweden)

    HUANG Meixia

    2012-07-01

    Full Text Available In order to study the chip formation mechanism in metal cutting process, based on finite element software ABAQUS, establish finite element model, and carry out numerical simulation on serrated chip formation of Ni-base superalloy GH4169 and ribbon chip formation of 45# steel respectively.In addition, analyze the influence law of three factors (cutting speed, feed rate, back cutting depth on cutting force and the distribution rule of cutting heat in serrated chip formation of GH4169.  

  16. Mechanically Flexible Active Silicon Chips and Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Using innovative chip thinning technology married with recently available packaging technology, this effort will produce Mechanically Flexible Multifunctional...

  17. Viral diagnosis in Indian livestock using customized microarray chips.

    Science.gov (United States)

    Yadav, Brijesh S; Pokhriyal, Mayank; Ratta, Barkha; Kumar, Ajay; Saxena, Meeta; Sharma, Bhaskar

    2015-01-01

    Viral diagnosis in Indian livestock using customized microarray chips is gaining momentum in recent years. Hence, it is possible to design customized microarray chip for viruses infecting livestock in India. Customized microarray chips identified Bovine herpes virus-1 (BHV-1), Canine Adeno Virus-1 (CAV-1), and Canine Parvo Virus-2 (CPV-2) in clinical samples. Microarray identified specific probes were further confirmed using RT-PCR in all clinical and known samples. Therefore, the application of microarray chips during viral disease outbreaks in Indian livestock is possible where conventional methods are unsuitable. It should be noted that customized application requires a detailed cost efficiency calculation.

  18. Router Architecture for Network on Chip Using FPGA

    Directory of Open Access Journals (Sweden)

    P. B. Domkondwar D. S. Chaudhari

    2012-04-01

    Full Text Available On Single chip integration of storage and computational block has becoming feasible due to continuous shrinkage of CMOS technology [1]. Field programmable gate arrays (FPGA’s are power efficient devices [3] support more complex design with good performance and low cost [6]. For effective global on-chip communication, on-chip routers provide essential routing functionality with low complexity and relatively high performance [1]. Routers implemented within FPGA can give better performance with reduced area and hence reduced power consumption [4]. This paper will provide an overview of related work for on-chip router architectures.

  19. The drying of wood chips with surplus heat in Norway

    Energy Technology Data Exchange (ETDEWEB)

    Nordhagen, E. [Norwegian Forest and Landscape Inst., As (Norway). Dept. of Forest Resources, Forest Operations and Economics

    2010-07-01

    The study evaluated a wood chip drying procedure that used surplus heat from 2 hydroelectric power plants in western Norway. The wood was chipped and then loaded into the dryer using a tractor-trailer and a container. Warm air from the plants was funnelled into the dryer from perforated floors in the plants and an electric fan. Trials of the procedure were conducted to determine the drying capacity of the trailer and container. The study showed that the temperature and the moisture content of the wood chips varied over the course of the drying period. The chips located at the bottom dried first. The moisture content in the chip ranged between 66.1 to 52.1 before drying and between 9.6 and 6.9 per cent after drying. No substantial difference in moisture content between wood chips located at the top and bottom of the piles was noted. The net calorific values of the wood chips ranged from 1340 to 2170 kWh per tonne before drying, and between 4710 to 4860 after drying. The study showed that the cheapest option for the production of wood chips is natural drying and chipping at the roadside.

  20. ANALYTICAL CHIP FORMATION MODEL OF MICRO-END-MILLING

    Institute of Scientific and Technical Information of China (English)

    LI Chengfeng; LAI Xinmin; LI Hongtao; PENG Linfa; NI Jun

    2008-01-01

    A new analytical chip formation model is proposed for micro-end-milling operations. The model calculates an instantaneous uncut chip thickness by considering the combination of exact trochoidal trajectory of the tool tip and tool run-out, while the simplified circular trajectory and the neglected run-out create negligible change in conventional-scale chip formation models. Newton-Raphson iterative method is employed during the calculation to obtain quadratic convergence. The proposed approach allows the calculation of instantaneous uncut chip thickness to be done accurately and rapidly, and the prediction accuracy of this model is also verified by comparing the simulation results to experimental cutting forces.

  1. Fabrication of Microfluidic Fiber Chip Detection System

    Institute of Scientific and Technical Information of China (English)

    Bo Su; Da-fu Cui; Chang-chun Liu; Xing Chen

    2006-01-01

    The diameter of the excitation beam was decreased greatly by integrating the fiber on the microfluidic chip as light propagation medium. The coupling efficiency of the fiber was improved with optical fiber collimation device coupling beam.The chip was placed in the darkroom to avoid the interference of the external light. The cost of the instrument was decreased with a high brightness blue LED as excitation source; the performance of the system was valuated by the determination of FITC fluorescein with a minimum detectable concentration of 2.2×10-8 mol/L, the Signal-to-Noise Ratio (SNR) S/N=5. The correlation coefficient of the detection system within the range of 1.8 × 10-7 mol/L~ 4 × 10-5mol/L was 0.9972.

  2. Design considerations for pixel readout chips

    CERN Document Server

    Fischer, P

    2003-01-01

    Pixel detectors are becoming a standard tracking component in modern particle physics experiment and find first applications in X-ray diffraction, medical imaging and astronomy. The amplification and the readout of the small signal charges from the pixel sensor require highly integrated ASICs in which several thousand low-noise charge-sensitive amplifiers are densely interspersed with fast data-processing logic. The reduction of crosstalk from the digital to the analog section is therefore crucial. The frequent demand for radiation tolerance requires special chip technologies or the use of deep sub-micron processes with suited design rules. This paper summarizes a few designs aspects particularly important for pixel readout chips.

  3. Invisibility Cloak Printed on a Photonic Chip.

    Science.gov (United States)

    Feng, Zhen; Wu, Bing-Hong; Zhao, Yu-Xi; Gao, Jun; Qiao, Lu-Feng; Yang, Ai-Lin; Lin, Xiao-Feng; Jin, Xian-Min

    2016-01-01

    Invisibility cloak capable of hiding an object can be achieved by properly manipulating electromagnetic field. Such a remarkable ability has been shown in transformation and ray optics. Alternatively, it may be realistic to create a spatial cloak by means of confining electromagnetic field in three-dimensional arrayed waveguides and introducing appropriate collective curvature surrounding an object. We realize the artificial structure in borosilicate by femtosecond laser direct writing, where we prototype up to 5,000 waveguides to conceal millimeter-scale volume. We characterize the performance of the cloak by normalized cross correlation, tomography analysis and continuous three-dimensional viewing angle scan. Our results show invisibility cloak can be achieved in waveguide optics. Furthermore, directly printed invisibility cloak on a photonic chip may enable controllable study and novel applications in classical and quantum integrated photonics, such as invisualising a coupling or swapping operation with on-chip circuits of their own. PMID:27329510

  4. On-chip plasmonic waveguide optical waveplate

    Science.gov (United States)

    Gao, Linfei; Huo, Yijie; Zang, Kai; Paik, Seonghyun; Chen, Yusi; Harris, James S.; Zhou, Zhiping

    2015-10-01

    Polarization manipulation is essential in almost every photonic system ranging from telecommunications to bio-sensing to quantum information. This is traditionally achieved using bulk waveplates. With the developing trend of photonic systems towards integration and miniaturization, the need for an on-chip waveguide type waveplate becomes extremely urgent. However, this is very challenging using conventional dielectric waveguides, which usually require complex 3D geometries to alter the waveguide symmetry and are also difficult to create an arbitrary optical axis. Recently, a waveguide waveplate was realized using femtosecond laser writing, but the device length is in millimeter range. Here, for the first time we propose and experimentally demonstrate an ultracompact, on-chip waveplate using an asymmetric hybrid plasmonic waveguide to create an arbitrary optical axis. The device is only in several microns length and produced in a flexible integratable IC compatible format, thus opening up the potential for integration into a broad range of systems.

  5. Ion trap in a semiconductor chip

    Science.gov (United States)

    Stick, D.; Hensinger, W. K.; Olmschenk, S.; Madsen, M. J.; Schwab, K.; Monroe, C.

    2006-01-01

    The electromagnetic manipulation of isolated atoms has led to many advances in physics, from laser cooling and Bose-Einstein condensation of cold gases to the precise quantum control of individual atomic ions. Work on miniaturizing electromagnetic traps to the micrometre scale promises even higher levels of control and reliability. Compared with `chip traps' for confining neutral atoms, ion traps with similar dimensions and power dissipation offer much higher confinement forces and allow unparalleled control at the single-atom level. Moreover, ion microtraps are of great interest in the development of miniature mass-spectrometer arrays, compact atomic clocks and, most notably, large-scale quantum information processors. Here we report the operation of a micrometre-scale ion trap, fabricated on a monolithic chip using semiconductor micro-electromechanical systems (MEMS) technology. We confine, laser cool and measure heating of a single 111Cd+ ion in an integrated radiofrequency trap etched from a doped gallium-arsenide heterostructure.

  6. Ion Trap in a Semiconductor Chip

    CERN Document Server

    Stick, D; Olmschenk, S; Madsen, M J; Schwab, K; Monroe, C

    2006-01-01

    The electromagnetic manipulation of isolated atoms has led to many advances in physics, from laser cooling and Bose-Einstein condensation of cold gases to the precise quantum control of individual atomic ion. Work on miniaturizing electromagnetic traps to the micrometer scale promises even higher levels of control and reliability. Compared with 'chip traps' for confining neutral atoms, ion traps with similar dimensions and power dissipation offer much higher confinement forces and allow unparalleled control at the single-atom level. Moreover, ion microtraps are of great interest in the development of miniature mass spectrometer arrays, compact atomic clocks, and most notably, large scale quantum information processors. Here we report the operation of a micrometer-scale ion trap, fabricated on a monolithic chip using semiconductor micro-electromechanical systems (MEMS) technology. We confine, laser cool, and measure heating of a single 111Cd+ ion in an integrated radiofrequency trap etched from a doped gallium...

  7. Invisibility Cloak Printed on a Photonic Chip

    Science.gov (United States)

    Feng, Zhen; Wu, Bing-Hong; Zhao, Yu-Xi; Gao, Jun; Qiao, Lu-Feng; Yang, Ai-Lin; Lin, Xiao-Feng; Jin, Xian-Min

    2016-01-01

    Invisibility cloak capable of hiding an object can be achieved by properly manipulating electromagnetic field. Such a remarkable ability has been shown in transformation and ray optics. Alternatively, it may be realistic to create a spatial cloak by means of confining electromagnetic field in three-dimensional arrayed waveguides and introducing appropriate collective curvature surrounding an object. We realize the artificial structure in borosilicate by femtosecond laser direct writing, where we prototype up to 5,000 waveguides to conceal millimeter-scale volume. We characterize the performance of the cloak by normalized cross correlation, tomography analysis and continuous three-dimensional viewing angle scan. Our results show invisibility cloak can be achieved in waveguide optics. Furthermore, directly printed invisibility cloak on a photonic chip may enable controllable study and novel applications in classical and quantum integrated photonics, such as invisualising a coupling or swapping operation with on-chip circuits of their own. PMID:27329510

  8. Redsharc: A Programming Model and On-Chip Network for Multi-Core Systems on a Programmable Chip

    OpenAIRE

    Kritikos, William V.; Andrew G. Schmidt; Ron Sass; Anderson, Erik K.; Matthew French

    2012-01-01

    The reconfigurable data-stream hardware software architecture (Redsharc) is a programming model and network-on-a-chip solution designed to scale to meet the performance needs of multi-core Systems on a programmable chip (MCSoPC). Redsharc uses an abstract API that allows programmers to develop systems of simultaneously executing kernels, in software and/or hardware, that communicate over a seamless interface. Redsharc incorporates two on-chip networks that directly implement the API to suppor...

  9. On-chip Ultrasonic Sample Preparation

    OpenAIRE

    Iranmanesh, Ida Sadat

    2015-01-01

    Acoustofluidics has become a well-established technology in the lab-on-a-chip scientific community. The technology involves primarily the manipulation of fluids and/or particles in microfluidic systems. It is used today for variety of applications such as handling, sorting, washing and separation of cells or micro-particles, and for mixing and pumping of fluids. When such manipulation functions are integrated in micro-devices, the technology has been used for clinical sample preparation as we...

  10. Imaging Cold Molecules on a Chip

    OpenAIRE

    Marx, S.; Adu Smith, D.; Abel, M.; Zehentbauer, T.; Meijer, G.J.M.; Santambrogio, G.

    2013-01-01

    We present the integrated imaging of cold molecules in a microchip environment. The on-chip detection is based on resonance-enhanced multiphoton ionization, which is quantum state selective and generally applicable. We demonstrate and characterize time-resolved spatial imaging and subsequently use it to analyze the effect of a phase-space manipulation sequence aimed at compressing the velocity distribution of a molecular ensemble with a view to future high-resolution spectroscopic studies. Th...

  11. Cold molecular ions on a chip

    OpenAIRE

    Mokhberi, A.; Willitsch, S.

    2014-01-01

    We report the sympathetic cooling and Coulomb crystallization of molecular ions above the surface of an ion-trap chip. N$_2^+$ and CaH$^+$ ions were confined in a surface-electrode radiofrequency ion trap and cooled by the interaction with laser-cooled Ca$^{+}$ ions to secular translational temperatures in the millikelvin range. The configuration of trapping potentials generated by the surface electrodes enabled the formation of planar bicomponent Coulomb crystals and the spatial separation o...

  12. On-Chip Single Plasmon Detection

    OpenAIRE

    Heeres, Reinier W.; Dorenbos, Sander N.; Koene, Benny; Solomon, Glenn S.; Kouwenhoven, Leo P.; Zwiller, Valery

    2010-01-01

    Surface plasmon polaritons (plasmons) have the potential to interface electronic and optical devices. They could prove extremely useful for integrated quantum information processing. Here we demonstrate on-chip electrical detection of single plasmons propagating along gold waveguides. The plasmons are excited using the single-photon emission of an optically emitting quantum dot. After propagating for several micrometers, the plasmons are coupled to a superconducting detector in the near-field...

  13. Pyramidal micromirrors for microsystems and atom chips

    Science.gov (United States)

    Trupke, M.; Ramirez-Martinez, F.; Curtis, E. A.; Ashmore, J. P.; Eriksson, S.; Hinds, E. A.; Moktadir, Z.; Gollasch, C.; Kraft, M.; Vijaya Prakash, G.; Baumberg, J. J.

    2006-02-01

    Concave pyramids are created in the (100) surface of a silicon wafer by anisotropic etching in potassium hydroxide. High quality micromirrors are then formed by sputtering gold onto the smooth silicon (111) faces of the pyramids. These mirrors show great promise as high quality optical devices suitable for integration into micro-optoelectromechanical systems and atom chips. We have shown that structures of this shape can be used to laser-cool and hold atoms in a magneto-optical trap.

  14. Dynamically Reconfigurable Systems-on-Chip

    OpenAIRE

    Stechele, Walter

    2006-01-01

    The design space for dynamically reconfigurable SoCs can be seen in three dimensions: 1) the system architecture for computation and communication, ranging from dataflow-oriented dedicated logic blocks to instruction flow-oriented microprocessor cores, from dedicated point-to-point connections to Networks-on-Chip. 2) the granularity of reconfigurable elements, ranging from simple logic Look-Up-Tables to complex hardware accelerator engines and reconfigurable interconnect structures. 3) the co...

  15. Integration of optoelectronic technologies for chip-to- chip interconnections and parallel pipeline processing

    Science.gov (United States)

    Wu, Jenming

    Digital information services such as multimedia systems and data communications require the processing and transfer of tremendous amount of data. These data need to be stored, accessed and delivered efficiently and reliably at high speed for various user applications. This represents a great challenge for current electronic systems. Electronics is effective in providing high performance processing and computation, but its input/outputs (I/Os) bandwidth is unable to scale with its processing power. The signal I/Os or interconnections are needed between processors and input devices, between processors for multiprocessor systems, and between processors and storage devices. Novel chip-to-chip interconnect technologies are needed to meet this challenge. This work integrates optoelectronic technologies for chip-to-chip interconnects and parallel pipeline processing. Photonic and electronic technologies are complementary to each other in the sense that electronics is more suitable for high-speed, low cost computation, and photonics is more suitable for high-bandwidth information transmission. Smart pixel technology uses electronics for logic switching and optics for chip-to- chip interconnects, thus combining the abilities of photonics and electronics nicely. This work describes both vertical and horizontal integration of smart pixel technologies for chip-to-chip optical interconnects and its applications. We present smart pixel VLSI designs in both hybrid CMOS/MQW smart pixel and monolithic GaAs smart pixel technologies. We use the CMOS/MQW technology for smart pixel array cellular logic (SPARCL) processors for SIMD parallel pipeline processing. We have tested the chip and constructed a prototype system for device characterization and system demonstration. We have verified the functionality of the system and characterized the electrical functions of the chip and the optoelectronic properties of the MQW devices. We have developed algorithms that utilize SPARCL for various

  16. An all-solid-state, WDM silicon photonic digital link for chip-to-chip communications.

    Science.gov (United States)

    Thacker, Hiren D; Zheng, Xuezhe; Lexau, Jon; Shafiiha, Roshanak; Shubin, Ivan; Lin, Shiyun; Djordjevic, Stevan; Amberg, Philip; Chang, Eric; Liu, Frankie; Simons, John; Lee, Jin-Hyoung; Abed, Arin; Liang, Hong; Luo, Ying; Yao, Jin; Feng, Dazeng; Asghari, Mehdi; Ho, Ron; Raj, Kannan; Cunningham, John E; Krishnamoorthy, Ashok V

    2015-05-18

    We describe a multiwavelength hybrid-integrated solid-state link on a 3 µm silicon-on-insulator (SOI) nanophotonic platform. The link spans three chips and employs germanium-silicon electroabsorption waveguide modulators, silicon transport waveguides, echelle gratings for multiplexing and demultiplexing, and pure germanium waveguide photo-detectors. The 8λ WDM Tx and Rx components are interconnected via a routing "bridge" chip using edge-coupled optical proximity communication. The packaged, retimed digital WDM link is demonstrated at 10 Gb/s and 10(-12) BER, with three wavelength channels consuming an on-chip power below 1.5 pJ/bit, excluding the external laser power.

  17. Routing algorithms in networks-on-chip

    CERN Document Server

    Daneshtalab, Masoud

    2014-01-01

    This book provides a single-source reference to routing algorithms for Networks-on-Chip (NoCs), as well as in-depth discussions of advanced solutions applied to current and next generation, many core NoC-based Systems-on-Chip (SoCs). After a basic introduction to the NoC design paradigm and architectures, routing algorithms for NoC architectures are presented and discussed at all abstraction levels, from the algorithmic level to actual implementation.  Coverage emphasizes the role played by the routing algorithm and is organized around key problems affecting current and next generation, many-core SoCs. A selection of routing algorithms is included, specifically designed to address key issues faced by designers in the ultra-deep sub-micron (UDSM) era, including performance improvement, power, energy, and thermal issues, fault tolerance and reliability.   ·         Provides a comprehensive overview of routing algorithms for Networks-on-Chip and NoC-based, manycore systems; ·         Describe...

  18. A single chip with multiple talents

    CERN Multimedia

    Francesco Poppi

    2010-01-01

    The Medipix chips developed at CERN are being used in a variety of fields: from medicine to education and back to high-tech engineering. The scene is set for a bright future for this versatile technology.   The Medipix chip. It didn’t take long for a brilliant team of physicists and engineers who were working on pixel detectors for the LHC to realize that the technology had great potential in medical imaging. This was the birth of the Medipix project. Fifteen years later, with the collaboration of 18 research institutes, the team has produced an advanced version of the initial ideas: Medipix3 is a device that can measure very accurately the position and energy of the photons (one by one) that hit the associated detector. Radiography and computed tomography (CT) use X-ray photons to study the human body. The different energies of the photons in the beam can be thought of as the colours of the X-ray spectrum. This is why the use of Medipix3 chips in such diagnostic techniques is referred...

  19. Chip breaking system for automated machine tool

    Science.gov (United States)

    Arehart, Theodore A.; Carey, Donald O.

    1987-01-01

    The invention is a rotary selectively directional valve assembly for use in an automated turret lathe for directing a stream of high pressure liquid machining coolant to the interface of a machine tool and workpiece for breaking up ribbon-shaped chips during the formation thereof so as to inhibit scratching or other marring of the machined surfaces by these ribbon-shaped chips. The valve assembly is provided by a manifold arrangement having a plurality of circumferentially spaced apart ports each coupled to a machine tool. The manifold is rotatable with the turret when the turret is positioned for alignment of a machine tool in a machining relationship with the workpiece. The manifold is connected to a non-rotational header having a single passageway therethrough which conveys the high pressure coolant to only the port in the manifold which is in registry with the tool disposed in a working relationship with the workpiece. To position the machine tools the turret is rotated and one of the tools is placed in a material-removing relationship of the workpiece. The passageway in the header and one of the ports in the manifold arrangement are then automatically aligned to supply the machining coolant to the machine tool workpiece interface for breaking up of the chips as well as cooling the tool and workpiece during the machining operation.

  20. Evaluation of Pressure Stable Chip-to-Tube Fittings Enabling High-Speed Chip-HPLC with Mass Spectrometric Detection.

    Science.gov (United States)

    Lotter, Carsten; Heiland, Josef J; Stein, Volkmar; Klimkait, Michael; Queisser, Marco; Belder, Detlev

    2016-08-01

    Appropriate chip-to-tube interfacing is an enabling technology for high-pressure and high-speed liquid chromatography on chip. For this purpose, various approaches, to connect pressure resistant glass chips with HPLC pumps working at pressures of up to 500 bar, were examined. Three side-port and one top-port connection approach were evaluated with regard to pressure stability and extra column band broadening. A clamp-based top-port approach enabled chip-HPLC-MS analysis of herbicides at the highest pressure and speed. PMID:27397738

  1. Evaluation of Pressure Stable Chip-to-Tube Fittings Enabling High-Speed Chip-HPLC with Mass Spectrometric Detection.

    Science.gov (United States)

    Lotter, Carsten; Heiland, Josef J; Stein, Volkmar; Klimkait, Michael; Queisser, Marco; Belder, Detlev

    2016-08-01

    Appropriate chip-to-tube interfacing is an enabling technology for high-pressure and high-speed liquid chromatography on chip. For this purpose, various approaches, to connect pressure resistant glass chips with HPLC pumps working at pressures of up to 500 bar, were examined. Three side-port and one top-port connection approach were evaluated with regard to pressure stability and extra column band broadening. A clamp-based top-port approach enabled chip-HPLC-MS analysis of herbicides at the highest pressure and speed.

  2. DVFS using clock scheduling for Multicore Systems-on-Chip and Networks-on-Chip

    OpenAIRE

    Yadav, Manoj Kumar

    2014-01-01

    A modern System-on-Chip (SoC) contains processor cores, application-specific process- ing elements, memory, peripherals, all connected with a high-bandwidth and low-latency Network-on-Chip (NoC). The downside of such very high level of integration and con- nectivity is the high power consumption. In CMOS technology this is made of a dynamic and a static component. To reduce the dynamic component, Dynamic voltage and Fre- quency Scaling (DVFS) has been adopted. Although DVFS is very effective ...

  3. Experiment list: SRX220827 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available n fetal lung fibroblast cells, growing, H3K4me3 ChIP || cell line=IMR90 || cell type=human fetal lung fibrob...last cell line || growth state=growing || chip antibody=anti-H3K4me3 http://dbarc

  4. Experiment list: SRX143798 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 50.2,45.7,17688 GSM918706: LICR ChipSeq WholeBrain Pol2 E14.5 source_name=WholeBrain || biomaterial_provider...pe=ChipSeq || datatype description=Chromatin IP Sequencing || cell=WholeBrain || ...cell organism=mouse || cell description=Whole Brain || cell sex=U || antibody=Pol2 || antibody antibodydescr

  5. Multiplex polymerase chain reaction (PCR) on a SU-8 chip

    DEFF Research Database (Denmark)

    Christensen, Troels Balmer; Bang, Dang Duong; Wolff, Anders

    2008-01-01

    We present the detection of Campylobacter at species level using multiplex PCR in a micro fabricated PCR chip. The chip is based on the polymer SU-8 that allows integration with different microfluidic components, e.g., sample pre-treatment before PCR, and DNA detection simultaneously with or afte...... surface modification by adding BSA to the PCR mix was utilized....

  6. Experiment list: SRX170376 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Diagnosis=Normal 9474255,92.7,4.5,398 GSM971949: HEK293 HP1a ChIPSeq; Homo sapiens; ChIP-Seq source_name=HEK293..., HP1a ChIP || cell line=HEK293 || chip antibody=anti-FLAG M2 affinity gel || antibody vendor=Sigma-Aldri

  7. Experiment list: SRX170377 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Diagnosis=Normal 11861200,76.8,8.0,229 GSM971950: HEK293 HP1b ChIPSeq; Homo sapiens; ChIP-Seq source_name=HEK293..., HP1b ChIP || cell line=HEK293 || chip antibody=anti-FLAG M2 affinity gel || antibody vendor=Sigma-Aldr

  8. Experiment list: SRX170373 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Diagnosis=Normal 12749066,94.0,7.9,19829 GSM971946: HEK293 Brd2 ChIPSeq; Homo sapiens; ChIP-Seq source_name=HEK293..., Brd2 ChIP || cell line=HEK293 || chip antibody=anti-FLAG M2 affinity gel || antibody vendor=Sigma-Al

  9. Experiment list: SRX170374 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Diagnosis=Normal 12901656,89.7,3.2,445 GSM971947: HEK293 Brd3 ChIPSeq; Homo sapiens; ChIP-Seq source_name=HEK293..., Brd3 ChIP || cell line=HEK293 || chip antibody=anti-FLAG M2 affinity gel || antibody vendor=Sigma-Aldr

  10. Experiment list: SRX170375 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Diagnosis=Normal 13813513,90.4,3.3,191 GSM971948: HEK293 Brd4 ChIPSeq; Homo sapiens; ChIP-Seq source_name=HEK293..., Brd4 ChIP || cell line=HEK293 || chip antibody=anti-FLAG M2 affinity gel || antibody vendor=Sigma-Aldr

  11. Experiment list: SRX262781 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available _name=NIH3T3_SRF_15 || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=SRF || chip antibody vendor=Santa Cruz Biotec...hnology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/e

  12. Experiment list: SRX262790 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available IH3T3_MRTFB_15 || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-B || chip antibody vendor=Santa Cruz Biotechn...ology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/eac

  13. Experiment list: SRX262785 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available H3T3_MRTFA_03 || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-A || chip antibody vendor=Santa Cruz Biotechno...logy http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/each

  14. Experiment list: SRX262787 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available IH3T3_MRTFA_LAT || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-A || chip antibody vendor=Santa Cruz Biotech...nology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/ea

  15. Experiment list: SRX262798 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 3T3_SAP1_15 || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=SAP-1a || chip antibody vendor=Santa Cruz Biotechnolo...gy http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/eachDa

  16. WAVELET BASED SPECTRAL CORRELATION METHOD FOR DPSK CHIP RATE ESTIMATION

    Institute of Scientific and Technical Information of China (English)

    Li Yingxiang; Xiao Xianci; Tai Hengming

    2004-01-01

    A wavelet-based spectral correlation algorithm to detect and estimate BPSK signal chip rate is proposed. Simulation results show that the proposed method can correctly estimate the BPSK signal chip rate, which may be corrupted by the quadratic characteristics of the spectral correlation function, in a low SNR environment.

  17. Experiment list: SRX119684 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 2,13603 GSM874990: ES.H3K79me2; Homo sapiens; ChIP-Seq source_name=H1 human Embryonic stem cell || cell line=H1 || treatment=diagnost...ic sample (pre-treatment) || chip antibody=H3K79me2 || chip antibody manufacturer=A

  18. Experiment list: SRX119679 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 8,18360 GSM874985: ES.H3K27me3; Homo sapiens; ChIP-Seq source_name=H1 human Embryonic stem cells || cell line=H1 || treatment=diagnos...tic sample (pre-treatment) || chip antibody=H3K27me3 || chip antibody manufacturer=

  19. Experiment list: SRX150585 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available -Barr Virus 32926476,94.0,12.0,2668 GSM935506: Harvard ChipSeq GM12878 NF-YA IgG-mus source_name=GM12878 || ...PgId=165&q=GM12878 || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq || data

  20. Experiment list: SRX150495 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available is=Adenocarcinoma 62508352,67.6,8.4,1556 GSM935416: Harvard ChipSeq HeLa-S3 ZZZ3 std source_name=HeLa-S3 || ...biomaterial_provider=ATCC || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq

  1. Experiment list: SRX150496 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ein-Barr Virus 63040797,85.0,19.7,1435 GSM935417: Harvard ChipSeq GM12878 SPT20 std source_name=GM12878 || b...gId=165&q=GM12878 || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq || datat

  2. Experiment list: SRX150568 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available is=Adenocarcinoma 59265240,72.4,16.4,4779 GSM935489: Harvard ChipSeq HeLa-S3 RPC155 std source_name=HeLa-S3 ...|| biomaterial_provider=ATCC || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipS

  3. Experiment list: SRX150661 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available is=Adenocarcinoma 59396606,71.7,11.1,1200 GSM935582: Harvard ChipSeq HeLa-S3 BRF1 std source_name=HeLa-S3 ||... biomaterial_provider=ATCC || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq

  4. Experiment list: SRX150514 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available is=Adenocarcinoma 50607581,77.1,8.7,1126 GSM935435: Harvard ChipSeq HeLa-S3 BRF2 std source_name=HeLa-S3 || ...biomaterial_provider=ATCC || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq

  5. Experiment list: SRX150565 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available =Adenocarcinoma 54953593,74.3,12.2,1703 GSM935486: Harvard ChipSeq HeLa-S3 BDP1 std source_name=HeLa-S3 || b...iomaterial_provider=ATCC || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq |

  6. Experiment list: SRX150586 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available -Barr Virus 33195472,90.4,25.9,15633 GSM935507: Harvard ChipSeq GM12878 NF-YB IgG-mus source_name=GM12878 ||...?PgId=165&q=GM12878 || lab=Harvard || lab description=Struhl - Harvard University || datatype=ChipSeq || dat

  7. Experiment list: SRX183788 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available idin ChIP || chip antibody=Strepdavidin http://dbarchive.biosciencedbc.jp/kyushu-u/...us musculus; ChIP-Seq source_name=nTreg cells, Foxo1tagBirA mice || cell type=nTreg, Foxo1tagBirA strepdav

  8. Experiment list: SRX682274 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available IPseq; Mus musculus; ChIP-Seq source_name=CD4+ cells, Foxo1tagBirA mice || strain=C57BL/6 || cell type=CD4+, Foxo1tagBirA strepdavid...in ChIP || chip antibody=Strepdavidin http://dbarchive.bi

  9. Experiment list: SRX262792 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available H3T3_MRTFB_UO || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-B || chip antibody vendor=Santa Cruz Biotechno...logy http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/each

  10. Experiment list: SRX262789 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available H3T3_MRTFB_03 || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-B || chip antibody vendor=Santa Cruz Biotechno...logy http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/each

  11. Experiment list: SRX957683 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available GSM1635075: lens H3K4me1 ChIPseq; Mus musculus; ChIP-Seq source_name=newborn lens, H3K4me1 ChIP || strain/b...ackground=CD-1 || developmental stage=newborn || age=P1 || tissue=lens || chip an

  12. Experiment list: SRX957685 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 329 GSM1635077: lens H3K4me3 ChIPseq; Mus musculus; ChIP-Seq source_name=newborn lens, H3K4me3 ChIP || strai...n/background=CD-1 || developmental stage=newborn || age=P1 || tissue=lens || chip

  13. Experiment list: SRX957687 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 82 GSM1635079: lens H3K27ac ChIPseq; Mus musculus; ChIP-Seq source_name=newborn lens, H3K27ac ChIP || strain.../background=CD-1 || developmental stage=newborn || age=P1 || tissue=lens || chip

  14. Experiment list: SRX957680 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 5,1951 GSM1635072: lens Pax6 ChIPseq; Mus musculus; ChIP-Seq source_name=newborn lens, Pax6 ChIP || strain/b...ackground=CD-1 || developmental stage=newborn || age=P1 || tissue=lens || chip an

  15. Experiment list: SRX957695 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 6 GSM1635087: lens H3K27me3 ChIPseq; Mus musculus; ChIP-Seq source_name=newborn lens, H3K27me3 ChIP || strai...n/background=CD-1 || developmental stage=newborn || age=P1 || tissue=lens || chip

  16. Experiment list: SRX791596 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available idered part of the BASAL GANGLIA. 172081391,94.4,6.9,1090 GSM1556658: C Input; Mus musculus; ChIP-Seq source_name=mouse cocai...ne NAc ChIP input || tissue=nucleus accumbens || chip antibody=input || strategy=ChIP-seq || treatment=Cocai

  17. Experiment list: SRX860883 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 98020: Fetal brain H3K27me3 rep1; Homo sapiens; ChIP-Seq source_name=Fetal_brain_H3K27me3 || developmental stage=12 weeks after gesta...tion || tissue=fetal brain || chip antibody=H3K27me3 || chip antibody vendor=CST ht

  18. Experiment list: SRX860903 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 040: Fetal liver H3K27me3 rep1; Homo sapiens; ChIP-Seq source_name=Fetal_liver_H3K27me3 || developmental stage=12 weeks after gestati...on || tissue=fetal liver || chip antibody=H3K27me3 || chip antibody vendor=CST http

  19. The Cutting Process, Chips and Cutting Forces in Machining CFRP

    DEFF Research Database (Denmark)

    Koplev, A.; Lystrup, Aage; Vorm, T.

    1983-01-01

    The cutting of unidirectional CFRP, perpendicular as well as parallel to the fibre orientation, is examined. Shaping experiments, ‘quick-stop’ experiments, and a new chip preparation technique are used for the investigation. The formation of the chips, and the quality of the machined surface...

  20. Experiment list: SRX213410 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available GSM1058733: MS OVX K27me3 ChIPSeq; Mus musculus; ChIP-Seq GEO Accession=GSM1058733 || cell type=Mammary stem cells || state=ovariecto...mized || chip antibody=Histone H3 trimethyl Lys27 || strain=FVB/N || chip antibody

  1. Experiment list: SRX213419 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 058742: Luminal OVX K27me3 ChIPSeq; Mus musculus; ChIP-Seq source_name=mammary gland || cell type=Luminal cells || state=ovariectomiz...ed || chip antibody=Histone H3 trimethyl Lys27 || strain=FVB/N || chip antibody man

  2. Experiment list: SRX213409 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1058732: MS OVX K4me3 ChIPSeq; Mus musculus; ChIP-Seq source_name=mammary gland || cell type=Mammary stem cells || state=ovariectomiz...ed || chip antibody=Histone H3 trimethyl Lys4 || strain=FVB/N || chip antibody manu

  3. Experiment list: SRX080157 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX080157 hg19 TFs and others MYC Blood K-562 Primary Tissue=Blood|Tissue Diagnosis=Leukemia Chronic...l line=K562 || cell type=chronic myeloid leukemia || chip_antibody_provider=Santa Cruz || chip_antibody_cata

  4. Experiment list: SRX080155 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX080155 hg19 TFs and others MYC Blood K-562 Primary Tissue=Blood|Tissue Diagnosis=Leukemia Chronic...l line=K562 || cell type=chronic myeloid leukemia || chip_antibody_provider=Santa Cruz || chip_antibody_cata

  5. Experiment list: SRX080158 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ssue Diagnosis=Leukemia Chronic Myelogenous 15653948,90.2,10.7,16821 GSM748554: K562 PolII REP1 source_name=...K562_PolII || cell line=K562 || cell type=chronic myeloid leukemia || chip_antibody_provider=Covance || chip

  6. Experiment list: SRX080156 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX080156 hg19 TFs and others MYC Blood K-562 Primary Tissue=Blood|Tissue Diagnosis=Leukemia Chronic...l line=K562 || cell type=chronic myeloid leukemia || chip_antibody_provider=Santa Cruz || chip_antibody_cata

  7. Experiment list: SRX080159 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ssue Diagnosis=Leukemia Chronic Myelogenous 28835681,89.7,37.5,23402 GSM748555: K562 PolII REP2 source_name=...K562_PolII || cell line=K562 || cell type=chronic myeloid leukemia || chip_antibody_provider=Covance || chip

  8. Experiment list: SRX037430 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available =peripheral blood mononuclear cells 14488927,12.8,2.8,1378 GSM648492: Treg-H3K4me1 source_name=Treg cells fr...om PBMC, normal || gender=male || cell type=Treg cells || chip antibody=H3K4me1 || chip antibody vendor=Abca

  9. Experiment list: SRX037431 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available =peripheral blood mononuclear cells 20224353,15.6,11.0,26171 GSM648493: Treg-H3K4me3 source_name=Treg cells ...from PBMC, normal || gender=male || cell type=Treg cells || chip antibody=H3K4me3 || chip antibody vendor=Ab

  10. Experiment list: SRX262791 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nology http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/ea...IH3T3_MRTFB_LAT || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=MRTF-B || chip antibody vendor=Santa Cruz Biotech

  11. Experiment list: SRX262797 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 3T3_SAP1_03 || cell line=NIH3T3 fibroblasts || genotype=normal || chip antibody=SAP-1a || chip antibody vendor=Santa Cruz Biotechnolo...gy http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/eachDa

  12. Experiment list: SRX031215 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available clonal anti-FLAG (clone M2), Sigma, Catalog A2220 (lot N/A) || chip antibody details=HA: mouse monoclonal...ource_name=mouse ES cells || strain=129J || cell type=mESCs || genotype/variation=FH-Prdm14 || chip antibody details=FLAG: mouse mono

  13. Experiment list: SRX031216 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nal anti-FLAG (clone M2), Sigma, Catalog A2220 (lot N/A) || chip antibody details=HA: mouse monoclonal...rce_name=mouse ES cells || strain=129J || cell type=mESCs || genotype/variation=wildtype || chip antibody details=FLAG: mouse monoclo

  14. Experiment list: SRX821807 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e=PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnol...ogies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/ea

  15. Experiment list: SRX1038538 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 695731: H7660 Red1 ChIP in rec8 delta biological replicate 2; Saccharomyces cerevisiae; ChIP-Seq source_name...=Red1 ChIP in rec8 delta biological replicate 2 || strain=sk1 || meiotic timepoint=3 hour || genotype=rec8 d

  16. Experiment list: SRX1038542 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1695735: H8083 Red1 ChIP in pREC8-SCC1 biological replicate 2; Saccharomyces cerevisiae; ChIP-Seq source_nam...e=Red1 ChIP in pREC8-SCC1 biological replicate 2 || strain=sk1 || meiotic timepoint=3 hour || genotype=pREC8

  17. Experiment list: SRX1038526 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 695719: H119 Red1 ChIP biological replicate 2; Saccharomyces cerevisiae; ChIP-Seq source_name=Red1 ChIP of H119 biological...SRX1038526 sacCer3 TFs and others RED1 Yeast strain SK1 NA 6440074,94.5,38.5,0 GSM1

  18. Experiment list: SRX1038541 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1695734: H8083 Red1 ChIP in pREC8-SCC1 biological replicate 1; Saccharomyces cerevisiae; ChIP-Seq source_nam...e=Red1 ChIP in pREC8-SCC1 biological replicate 1 || strain=sk1 || meiotic timepoint=3 hour || genotype=pREC8

  19. Experiment list: SRX1038525 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1695718: H119 Red1 ChIP biological replicate 1; Saccharomyces cerevisiae; ChIP-Seq source_name=Red1 ChIP of H119 biological...SRX1038525 sacCer3 TFs and others RED1 Yeast strain SK1 NA 22907545,92.4,48.3,0 GSM

  20. Experiment list: SRX1038534 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 95727: H6309 Smc3 ChIP biological replicate 1; Saccharomyces cerevisiae; ChIP-Seq source_name=Smc3 ChIP of H6309 biological...SRX1038534 sacCer3 TFs and others SMC3 Yeast strain SK1 NA 1594898,87.7,9.1,0 GSM16

  1. Experiment list: SRX1038532 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 695725: H4471 Rec8 ChIP biological replicate 2; Saccharomyces cerevisiae; ChIP-Seq source_name=Red1 ChIP of H4471 biological...SRX1038532 sacCer3 TFs and others RED1 Yeast strain SK1 NA 1426016,92.6,26.8,0 GSM1

  2. Experiment list: SRX1038537 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1695730: H6200 Red1 ChIP in rec8 delta biological replicate 1; Saccharomyces cerevisiae; ChIP-Seq source_nam...e=Red1 ChIP in rec8 delta biological replicate 1 || strain=sk1 || meiotic timepoint=3 hour || genotype=rec8

  3. Exploration within the Network-on-Chip Paradigm

    NARCIS (Netherlands)

    Wolkotte, Pascal Theodoor

    2009-01-01

    A general purpose processor used to consist of a single processing core, which performed and controlled all tasks on the chip. Its functionality and maximum clock frequency grew steadily over the years. Due to the continuous increase of the number of transistors available on-chip and the operational

  4. The three-dimensional structure of human erythrocyte aquaporin CHIP.

    Science.gov (United States)

    Walz, T; Smith, B L; Agre, P; Engel, A

    1994-07-01

    Water-permeable membranes of several plant and mammalian tissues contain specific water channel proteins, the 'aquaporins'. The best characterized aquaporin is CHIP, a 28 kDa red blood cell channel-forming integral protein. Isolated CHIP and Escherichia coli lipids may be assembled into 2-D crystals for structural analyses. Here we present (i) a structural characterization of the solubilized CHIP oligomers, (ii) projections of CHIP arrays after negative staining or metal-shadowing, and (iii) the 3-D structure at 1.6 nm resolution. Negatively stained CHIP oligomers exhibited a side length of 6.9 nm with four-fold symmetry, and a mass of 202 +/- 3 kDa determined by scanning transmission electron microscopy. Reconstituted into lipid bilayers, CHIP formed 2-D square lattices with unit cell dimensions a = b = 9.6 nm and a p422(1) symmetry. The 3-D map revealed that CHIP tetramers contain central stain-filled depressions about the fourfold axis. These cavities extend from both sides into the transbilayer domain of the molecule leaving only a thin barrier to be penetrated by the water pores. Although CHIP monomers behave as independent pores, we propose that their particular structure requires tetramerization for stable integration into the bilayer. PMID:7518771

  5. Experiment list: SRX200052 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 4 GSM1023626: LaminA ChIP, HGPS, p16, rep2; Homo sapiens; ChIP-Seq source_name=patient forearm skin biopsy, ...lamin ChIP || disease status=Hutchinson-Gilford progeria syndrome || tissue=forearm skin biopsy || cell type

  6. Experiment list: SRX200048 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 7 GSM1023622: LaminA ChIP, Father, p16, rep2; Homo sapiens; ChIP-Seq source_name=normal forearm skin biopsy,... lamin ChIP || disease status=normal || tissue=forearm skin biopsy || cell type=fibroblasts || gender=male |

  7. Experiment list: SRX200038 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available M1023612: H3K27me3 ChIP, Father, p19; Homo sapiens; ChIP-Seq source_name=normal forearm skin biopsy, H3K27me...3 ChIP || disease status=normal || tissue=forearm skin biopsy || cell type=fibroblasts || gender=male || cel

  8. Experiment list: SRX200046 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available GSM1023620: LaminA ChIP, Father, p16, rep1; Homo sapiens; ChIP-Seq source_name=normal forearm skin biopsy, ...lamin ChIP || disease status=normal || tissue=forearm skin biopsy || cell type=fibroblasts || gender=male ||

  9. Experiment list: SRX200042 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 1023616: H3K27me3 ChIP, HGPS, p14; Homo sapiens; ChIP-Seq source_name=patient forearm skin biopsy, H3K27me3 ...ChIP || disease status=Hutchinson-Gilford progeria syndrome || tissue=forearm skin biopsy || cell type=fibro

  10. Experiment list: SRX200044 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available M1023618: H3K27me3 ChIP, HGPS, p17; Homo sapiens; ChIP-Seq source_name=patient forearm skin biopsy, H3K27me3... ChIP || disease status=Hutchinson-Gilford progeria syndrome || tissue=forearm skin biopsy || cell type=fibr

  11. Experiment list: SRX200050 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available GSM1023624: LaminA ChIP, HGPS, p16, rep1; Homo sapiens; ChIP-Seq source_name=patient forearm skin biopsy, l...amin ChIP || disease status=Hutchinson-Gilford progeria syndrome || tissue=forearm skin biopsy || cell type=

  12. Experiment list: SRX200040 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 14: H3K27me3 ChIP, Age Control, p17; Homo sapiens; ChIP-Seq source_name=normal skin biopsy, H3K27me3 ChIP ||... disease status=normal || tissue=skin biopsy || cell type=fibroblasts || gender=female || cell line=AG08470

  13. Experiment list: SRX1338947 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ription=Progenitor cells from which all blood cells derive. 38987751,98.2,6.0,267 GSM1909031: Resistant line ChIP input...tion=Resistant || strain=C57BL/6 || chip antibody=none (input) http://dbarchive.b

  14. Experiment list: SRX365696 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e_name=Kc167_CP190_ChIP-seq || cell line=Kc167 || chip antibody=CP190 rabbit || chip antibody reference=PMID:21852534 || input... used=input-b http://dbarchive.biosciencedbc.jp/kyushu-u/dm3/ea

  15. Experiment list: SRX671992 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ; Mus musculus; ChIP-Seq source_name=embryonic stem cells, TC11, empty vector, input || strain/background=12...9/Ola || transchromosomic=hsa11 || plasmid=empty vector || chip_or_input=input DNA || chip antibody=none ||

  16. Experiment list: SRX081812 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available 751461: F1i ChIP Seq H3K27ac (GAII) source_name=Frontal cortex || strain=129X1/SvJ x Cast/EiJ || chip-antibody=H3K27ac || vendor=Acti...ve Motif, AM39133 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/eachData/bw/SRX081

  17. Experiment list: SRX063290 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ype/variation=t(4;14)-associated NSD2 allele knocked-out || gender=Female || chip antibody=anti-H3K36me2 || chip antibody vendor=Acti...ve Motif http://dbarchive.biosciencedbc.jp/kyushu-u/hg19

  18. Hardware support for CSP on a Java chip multiprocessor

    DEFF Research Database (Denmark)

    Gruian, Flavius; Schoeberl, Martin

    2013-01-01

    Due to memory bandwidth limitations, chip multiprocessors (CMPs) adopting the convenient shared memory model for their main memory architecture scale poorly. On-chip core-to-core communication is a solution to this problem, that can lead to further performance increase for a number of multithread...

  19. Experiment list: SRX507382 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available + (wildtype) || age of animals=1-5 day old || tissue=Ovaries || chip antibody=Anti-H3K9me3 || chip antibody ... Anti-H3K9me3- replicate#2; Drosophila melanogaster; ChIP-Seq source_name=WT_WT_Anti-H3K9me3 || strain=piwi/

  20. Experiment list: SRX507381 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available + (wildtype) || age of animals=1-5 day old || tissue=Ovaries || chip antibody=Anti-H3K9me3 || chip antibody ...Anti-H3K9me3 - replicate#1; Drosophila melanogaster; ChIP-Seq source_name=WT_WT_Anti-H3K9me3 || strain=piwi/

  1. Experiment list: SRX507380 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available + (wildtype) || age of animals=1-5 day old || tissue=Ovaries || chip antibody=anti-HP1 || chip antibody vend...1770: WT anti-HP1- replicate#2; Drosophila melanogaster; ChIP-Seq source_name=WT_WT_anti-HP1 || strain=piwi/

  2. Experiment list: SRX507383 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available + (wildtype) || age of animals=1-5 day old || tissue=Ovaries || chip antibody=Anti-H3K4me2 || chip antibody ... Anti-H3K4me2- replicate#1; Drosophila melanogaster; ChIP-Seq source_name=WT_WT_Anti-H3K4me2 || strain=piwi/

  3. Experiment list: SRX149660 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available sue Diagnosis=Carcinoma 164134451,96.9,12.9,25737 GSM937562: CDK8-ChIP enriched DNA, hypoxia, replicate1; Ho...mo sapiens; ChIP-Seq source_name=colorectal cancer cells, hypoxia, CDK8 ChIP || cell line=HCT116 || treatment=24hrs hypoxia

  4. Experiment list: SRX149661 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available sue Diagnosis=Carcinoma 60114830,96.8,20.7,14454 GSM937563: CDK8-ChIP enriched DNA, hypoxia, replicate2; Hom...o sapiens; ChIP-Seq source_name=colorectal cancer cells, hypoxia, CDK8 ChIP || cell line=HCT116 || treatment=24hrs hypoxia

  5. Experiment list: SRX176067 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available sis=Carcinoma 6619400,91.7,7.2,13648 GSM984399: LNCAP H3K4ME3 vehicle; Homo sapiens; ChIP-Seq source_name=pr...ostate cancer cells || cell line=LNCaP || chip antibody=H3K4Me3 || chip antibody manufacturer=Millipore || treatment=EtOH vehicle

  6. Experiment list: SRX144524 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available neage=mesoderm|Description=parental cell type to lymphoblastoid cell lines 4766716,6.2,89.4,0 GSM922969: NRF2 ChIP vehicle... treated pilot; Homo sapiens; ChIP-Seq source_name=NRF2 ChIP vehicle treated || biomaterial_pr

  7. Experiment list: SRX176054 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nosis=Carcinoma 13338805,91.2,4.9,792 GSM984386: LNCAP AR vehicle; Homo sapiens; ChIP-Seq source_name=prosta...te cancer cells || cell line=LNCaP || chip antibody=AR || chip antibody manufacturer=Abcam || treatment=EtOH vehicle

  8. Experiment list: SRX176057 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nosis=Carcinoma 21582823,90.1,7.3,1074 GSM984389: 22RV1 AR vehicle; Homo sapiens; ChIP-Seq source_name=prost...ate cancer cells || cell line=22RV1 || chip antibody=AR || chip antibody manufacturer=Abcam || treatment=EtOH vehicle

  9. Experiment list: SRX176063 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available =Carcinoma 11279321,95.5,3.6,13985 GSM984395: LNCAP ACH3 vehicle; Homo sapiens; ChIP-Seq source_name=prostat...e cancer cells || cell line=LNCaP || chip antibody=AcH3 || chip antibody manufacturer=Millipore || treatment=EtOH vehicle

  10. Experiment list: SRX821811 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e=PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnol...ogies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/ea

  11. Experiment list: SRX821808 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available pe=PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechno...logies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/e

  12. Experiment list: SRX821814 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available pe=PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechno...logies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/e

  13. Experiment list: SRX821798 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nologies http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/...riment type=PPARG ChIP-seq || strain=N/A || tissue=NA || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotech

  14. Experiment list: SRX821810 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e=PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnol...ogies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/ea

  15. Experiment list: SRX821817 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e=PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnol...ogies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/ea

  16. Experiment list: SRX821816 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e=PPARG ChIP-seq || tissue=SQ White Adipose Tissue || chip antibody=anti-PPAR? antibody || chip antibody vendor=Santa Cruz Biotechnol...ogies http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/ea

  17. Flow control in microfluidic chips : Material choice and smart design

    NARCIS (Netherlands)

    Debrauwer, P.; Emmelkamp, J.; Bolt, P.J.

    2009-01-01

    This paper describes a model and experiments to validate it for the design of bubble free chambers and channels in microfluidic chips. When handling liquids in a microfluidic chip problems may arise with entrapping air or liquid. These air and liquid bubbles deteriorate the efficiency of the process

  18. Design of an Enterobacteriaceae Pan-genome Microarray Chip

    DEFF Research Database (Denmark)

    Lukjancenko, Oksana; Ussery, David

    2010-01-01

    -density microarray chip has been designed, using 116 Enterobacteriaceae genome sequences, taking into account the enteric pan-genome. Probes for the microarray were checked in silico and performance of the chip, based on experimental strains from four different genera, demonstrate a relatively high ability...

  19. An addressable cell array for a platform of biosensor chips

    Science.gov (United States)

    Yang, Seungkyoung; Choi, Soo-hee; Jung, Moon Youn; Song, Kibong; Park, Jeong Won

    2013-05-01

    In order to detect interested matters in fields, various lab-on-a-chips where chemical, physical, or biological sensors are loaded have been developed. eNOSE can be a representative example among them. Because animals can sense 300~1000 different chemicals by olfactory system - smell -, the olfactory system has been spotlighted as new materials in the field of sensing. Those investigations, however, are usually focused on how to detect signals from the olfactory neurons or receptors loaded on chips and enhance sensing efficacy of chips. Therefore, almost of those chips are designed for only one material sensing. Multi-sensing using multi-channels will be needed when the olfactory systems are adopted well on chips. For multiple sensing, we developed an addressable cell array. The chip has 38 cell-chambers arranged in a circle shape and different cell types of thirty eight can be allocated with specific addresses on the chip without any complex valve system. In order to confirm the cell addressing, we loaded EGFP-transfected and empty vector-transfected HEK293a cells into inlets of the cell array in a planned address and those cells were positioned into each chamber by brief aspiration. The arrayed cells were confirmed as a specific pattern through EGFP and nuclei staining. This cell array which can generate address of sensor materials like cells with their own specification is expected to be applied to a platform for a biosensor chip at various sensing fields.

  20. Advanced Micro Narrows Gap in Race for New Chip

    Institute of Scientific and Technical Information of China (English)

    John Markoff; 张宁

    2004-01-01

    @@ Hoping to catch up with Intel and I. B. M. in an advanced chip-making technology, the semiconductor maker Advanced Micro Devices plans to announce Tuesday that it has begun to ship chips based on an advanced manufacturing process that is being used to build the next generation of processors.

  1. Experiment list: SRX245508 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available cell CTCF; Mus musculus; ChIP-Seq source_name=splenic B cells || chip antibody=CT...CF || chip antibody manufacturer=Millipore || cell type=splenic B cells || strain=C57BL/6 || cell surface ma

  2. Experiment list: SRX316310 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available cell type=mouse embryonic stem cells || genotype/variation=expressing Prdm4-EGFP || chip antibody=GFP (clone 3E6) Mouse IgG2a, Monoc...lonal Antibody || chip antibody vendor=Invitrogen http:/

  3. Experiment list: SRX309665 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available WT; Mus musculus; ChIP-Seq source_name=CD43 negative mouse resting B cells || str...issue of origin=spleen || cell type=CD43 negative mouse resting B cells || chip antibody=H3S28ph || chip ant

  4. Experiment list: SRX327768 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Site of Extraction=Effusion, Pleural|Tissue Diagnosis=Carcinoma Small Cell 49325280,95.0,26.6,19188 GSM11955...68: H2171 DMSO POL2 ChipSeq; Homo sapiens; ChIP-Seq source_name=Small Cell Lung Carcinoma || chip antibody=R

  5. Experiment list: SRX204900 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ction=Effusion, Pleural|Tissue Diagnosis=Carcinoma Small Cell 46274812,93.4,19.9,50407 GSM1038270: H2171 BRD...4; Homo sapiens; ChIP-Seq source_name=Small Cell Lung Carcinoma || chip antibody=Brd4 || chip antibody detai

  6. Brain-on-a-chip integrated neuronal networks

    NARCIS (Netherlands)

    Xie, Sijia

    2016-01-01

    The brain-on-a-chip technology aims to provide an efficient and economic in vitro platform for brain disease study. In the well-known literature on brain-on-a-chip systems, nonstructured surfaces were conventionally used for the cell attachment in a culture chamber, therefore the neuronal networks g

  7. Improving chip-to-chip precision in disposable microchip capillary electrophoresis devices with internal standards

    NARCIS (Netherlands)

    Bidulock, Allison C.E.; Berg, van den Albert; Eijkel, Jan C.T.

    2015-01-01

    To realize portable systems for routine measurements in point-of-care settings, MCE methods are required to be robust across many single-use chips. While it is well-known internal standards (ISTDs) improve run-to-run precision, a systematic investigation is necessary to determine the significance of

  8. A Single-Chip CMOS Pulse Oximeter with On-Chip Lock-In Detection

    Directory of Open Access Journals (Sweden)

    Diwei He

    2015-07-01

    Full Text Available Pulse oximetry is a noninvasive and continuous method for monitoring the blood oxygen saturation level. This paper presents the design and testing of a single-chip pulse oximeter fabricated in a 0.35 µm CMOS process. The chip includes photodiode, transimpedance amplifier, analogue band-pass filters, analogue-to-digital converters, digital signal processor and LED timing control. The experimentally measured AC and DC characteristics of individual circuits including the DC output voltage of the transimpedance amplifier, transimpedance gain of the transimpedance amplifier, and the central frequency and bandwidth of the analogue band-pass filters, show a good match (within 1% with the circuit simulations. With modulated light source and integrated lock-in detection the sensor effectively suppresses the interference from ambient light and 1/f noise. In a breath hold and release experiment the single chip sensor demonstrates consistent and comparable performance to commercial pulse oximetry devices with a mean of 1.2% difference. The single-chip sensor enables a compact and robust design solution that offers a route towards wearable devices for health monitoring.

  9. High curvature bending characterization of ultra-thin chips and chip-on-foil assemblies

    NARCIS (Netherlands)

    Ende, D. van den; Verhoeven, F.; Eijnden, P. van der; Kusters, R.; Sridhar, A.; Cauwe, M.; Brand, J. van den

    2013-01-01

    Ultra-thin chips of less than 20μm become flexible, allowing integration of silicon IC technology with highly flexible electronics. This combination allows for highly intelligent products of unprecedented thinness, flexibility and cost. Examples include sensor systems integrated into food packaging

  10. "Chips with Everything": A Laboratory Exercise for Comparing Subjective and Objective Measurements of Potato Chips

    Science.gov (United States)

    Davies, Cathy

    2005-01-01

    The following laboratory exercise was designed to aid student understanding of the differences between subjective and objective measurements. Students assess the color and texture of different varieties of potato chip (crisps) by means of an intensity rating scale and a rank test and objectively with a colorimeter and texture analyzer. For data…

  11. Isotachophoretic analysis using injection-moulded polystyrene chip devices

    International Nuclear Information System (INIS)

    A new type of miniaturized separation chip for performing isotachophoresis has been produced. The design uses polystyrene as a substrate material and incorporates carbon fibre loaded polystyrene drive and conductivity detection electrodes. This fully polymeric composition allows for the devices to be produced using injection moulding. Ultrasonic welding is used for sealing to give robust chips that can potentially be easily transported and used outside of a laboratory environment. A batch of devices was produced and tested with a number of inorganic cationic species as samples. The entire batch of 22 devices were successfully used for isotachophoretic separations. Good reproducibility was observed in the qualitative behaviour of the devices. For example, with lithium a relative step height ± standard deviation of 1.49 ± 0.01 was observed on a run-to-run basis with a single chip and of 1.47 ± 0.03 on a chip-to-chip basis over the entire batch of devices

  12. Modelling, Synthesis, and Configuration of Networks-on-Chips

    DEFF Research Database (Denmark)

    Stuart, Matthias Bo

    is an analytical method for deriving the worst-case traffic pattern caused by an application and the cache-coherence protocol in a cache-coherent shared-memory system. The contributions related to network-on-chip optimization problems consist of two parts: The development and evaluation of six heuristics......This thesis presents three contributions in two different areas of network-on-chip and system-on-chip research: Application modelling and identifying and solving different optimization problems related to two specific network-on-chip architectures. The contribution related to application modelling...... for solving the network synthesis problem in the MANGO network-on-chip, and the identification and formalization of the ReNoC configuration problem together with three heuristics for solving it....

  13. Progress in Atom Chips and the Integration of Optical Microcavities

    Science.gov (United States)

    Hinds, E. A.; Trupke, M.; Darquie, B.; Goldwin, J.; Dutier, G.

    2008-04-01

    We review recent progress at the Centre for Cold Matter in developing atom chips. An important advantage of miniaturizing atom traps on a chip is the possibility of obtaining very tight trapping structures with the capability of manipulating atoms on the micron length scale. We recall some of the pros and cons of bringing atoms close to the chip surface, as is required in order to make small static structures, and we discuss the relative merits of metallic, dielectric and superconducting chip surfaces. We point out that the addition of integrated optical devices on the chip can enhance its capability through single atom detection and controlled photon production. Finally, we review the status of integrated microcavities that have recently been demonstrated at our Centre and discuss their prospects for future development.

  14. Stem-end defect in chipping potatoes (Solanum tuberosum L.) as influenced by mild environmental stresses

    Science.gov (United States)

    Global consumption of potato (Solanum tuberosum, L.) continues to shift from fresh potatoes to value-added processed food products such as potato chips. One serious tuber quality defect of chipping potatoes is stem-end chip defect, which results in chips with dark vasculature and adjacent tissues at...

  15. An energy-efficient Network-on-Chip for a heterogeneous tiled reconfigurable System-on-Chip

    OpenAIRE

    Kavaldjiev, Nikolay; Smit, Gerard J.M.

    2004-01-01

    This paper proposes a Network-on-Chip architecture that offers high flexibility and performance. It is used in a System-on-Chip platform for future multimedia mobile devices. The network is packet switching wormhole network with virtual-channel flow control and source routing. The initial implementation results for a network router show its feasibility and size comparable with other available solutions.

  16. Design of Networks-on-Chip for Real-Time Multi-Processor Systems-on-Chip

    DEFF Research Database (Denmark)

    Sparsø, Jens

    2012-01-01

    This paper addresses the design of networks-on-chips for use in multi-processor systems-on-chips - the hardware platforms used in embedded systems. These platforms typically have to guarantee real-time properties, and as the network is a shared resource, it has to provide service guarantees...

  17. 75 FR 447 - In the Matter of Certain Semiconductor Chips With Minimized Chip Package Size and Products...

    Science.gov (United States)

    2010-01-05

    ..., 2007. 73 FR 2276 (Jan. 14, 2008). The complaint alleged violations of section 337 of the Tariff Act of... it determined to review, and on remedy, the public interest and bonding. 74 FR 57192 (Nov. 4, 2009... COMMISSION In the Matter of Certain Semiconductor Chips With Minimized Chip Package Size and...

  18. Energy Harvesting Chip and the Chip Based Power Supply Development for a Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Dasheng Lee

    2008-12-01

    Full Text Available In this study, an energy harvesting chip was developed to scavenge energy from artificial light to charge a wireless sensor node. The chip core is a miniature transformer with a nano-ferrofluid magnetic core. The chip embedded transformer can convert harvested energy from its solar cell to variable voltage output for driving multiple loads. This chip system yields a simple, small, and more importantly, a battery-less power supply solution. The sensor node is equipped with multiple sensors that can be enabled by the energy harvesting power supply to collect information about the human body comfort degree. Compared with lab instruments, the nodes with temperature, humidity and photosensors driven by harvested energy had variation coefficient measurement precision of less than 6% deviation under low environmental light of 240 lux. The thermal comfort was affected by the air speed. A flow sensor equipped on the sensor node was used to detect airflow speed. Due to its high power consumption, this sensor node provided 15% less accuracy than the instruments, but it still can meet the requirement of analysis for predicted mean votes (PMV measurement. The energy harvesting wireless sensor network (WSN was deployed in a 24-hour convenience store to detect thermal comfort degree from the air conditioning control. During one year operation, the sensor network powered by the energy harvesting chip retained normal functions to collect the PMV index of the store. According to the one month statistics of communication status, the packet loss rate (PLR is 2.3%, which is as good as the presented results of those WSNs powered by battery. Referring to the electric power records, almost 54% energy can be saved by the feedback control of an energy harvesting sensor network. These results illustrate that, scavenging energy not only creates a reliable power source for electronic devices, such as wireless sensor nodes, but can also be an energy source by building an

  19. Wood harvesting as chunkwood chips and multi-stage chipping; Puun korjuu palahakkeena ja monivaiheinen lastuaminen

    Energy Technology Data Exchange (ETDEWEB)

    Kaipainen, H.; Seppaenen, V.

    1996-12-31

    The task for the year 1995 was to define the preliminary results of the previous years, to measure the productivity of a harvester, designed for production of chunkwood, and the properties of the chunks. The costs of the PALAPUU method from the felling site to pulpwood chips were to be examined on this basis. Because the prototype of the harvester was not yet available for field tests, the costs were partially calculated on the basis of previous measurements, completed by productivity data obtained from the time-consumption measurements of a multi-tree harvester, applied with minor alteration for this purpose. According to the calculations the PALAPUU method cannot compete with partial-tree or shortwood methods. The profitability of the method could be improved by adding the transportation density and the productivity of the harvester. It is also possible to procure timber to the mill as partial-trees and to chunk it while feeding it into the drum. Chipping tests were made using the steel-frame-chipper owned by VTT Construction Technology. The blade construction of the chipper was changed so, that it was possible to adjust the cutting thickness of the chips to 4 mm, while in the previous mill-tests it had been 6 mm. The chips were used for cooking tests in the Department of Chemistry of the University of Jyvaeskylae. The results showed that the thinner chips were cooked further under the same cooking conditions. By using the chunkwood method it is possible to harvest 10-70 more biomass for the mills, than it is possible in the pulpwood harvesting

  20. Heat toxicant contaminant mitigation in potato chips

    DEFF Research Database (Denmark)

    Mariotti, Maria; Cortes, Pablo; Fromberg, Arvid;

    2015-01-01

    Heating foods immersed in oil during frying provides many attractive sensorial attributes including taste, flavor and color. However, some toxic compounds formed during frying of potatoes such as furan and acrylamide may constitute an increased cancer risk for consumers. The objective of this work...... was to mitigate the furan and acrylamide formation in potato chips without increasing their oil uptake by optimizing the blanching treatment before final frying. Potato slices were blanched in order to simultaneously leach out ascorbic acid and reducing sugars, the most important precursors of furan...

  1. Heterogeneously integrated microsystem-on-a-chip

    Science.gov (United States)

    Chanchani, Rajen

    2008-02-26

    A microsystem-on-a-chip comprises a bottom wafer of normal thickness and a series of thinned wafers can be stacked on the bottom wafer, glued and electrically interconnected. The interconnection layer comprises a compliant dielectric material, an interconnect structure, and can include embedded passives. The stacked wafer technology provides a heterogeneously integrated, ultra-miniaturized, higher performing, robust and cost-effective microsystem package. The highly integrated microsystem package, comprising electronics, sensors, optics, and MEMS, can be miniaturized both in volume and footprint to the size of a bottle-cap or less.

  2. Computer System Design System-on-Chip

    CERN Document Server

    Flynn, Michael J

    2011-01-01

    The next generation of computer system designers will be less concerned about details of processors and memories, and more concerned about the elements of a system tailored to particular applications. These designers will have a fundamental knowledge of processors and other elements in the system, but the success of their design will depend on the skills in making system-level tradeoffs that optimize the cost, performance and other attributes to meet application requirements. This book provides a new treatment of computer system design, particularly for System-on-Chip (SOC), which addresses th

  3. Cooperative phenomena in superconducting atom-chips

    Energy Technology Data Exchange (ETDEWEB)

    Fuchs, Sebastian; Kubala, Bjoern; Ankerhold, Joachim [Institut fuer Theoretische Physik, Universitaet Ulm, Albert-Einstein-Allee 11, 89069 Ulm (Germany)

    2013-07-01

    We theoretically investigate the physics of hybrid quantum systems, where a cloud of cold atoms is coupled to superconducting microstructures, so called superconducting atom-chips. Coherent enhancement, due to the large number of atoms in the cloud, opens a path to the study of strong coupling effects, like superradiance/Dicke-physics in a decohering environment. A structured environment can be designed by embedding a Cooper pair box within the cavity. Moreover, in such a system the transfer of quantum information between the atomic cloud and the superconducting solid state system can be studied.

  4. Cooperative phenomena in superconducting atom-chips

    International Nuclear Information System (INIS)

    We theoretically investigate the physics of hybrid quantum systems, where a cloud of cold atoms is coupled to superconducting microstructures, so called superconducting atom-chips. Coherent enhancement, due to the large number of atoms in the cloud, opens a path to the study of strong coupling effects, like superradiance/Dicke-physics in a decohering environment. A structured environment can be designed by embedding a Cooper pair box within the cavity. Moreover, in such a system the transfer of quantum information between the atomic cloud and the superconducting solid state system can be studied.

  5. An Optical Inspection System Development for Defects on Multi-surfaces of Chips

    OpenAIRE

    Chen Ming-Fu; Chen Chih-Wen; Chou Chih-Chung; Chen Chih-Yen; Chiu Yen-Chi

    2016-01-01

    We proposed a new architecture with multiple pick and place heads to suck inspected chips and to be moved synchronously for acquiring the images of different surfaces on different chips at their corresponding acquisition stations. The computation loading of defect inspection for each chip also can be distributed because of sequential image acquisition. Considering the different computing loading of 6 surfaces of a chip, image acquisition for the front and back sides of chips is allocated at t...

  6. Investigation of formation mechanisms of chips in orthogonal cutting process

    Directory of Open Access Journals (Sweden)

    Ma W.

    2012-08-01

    Full Text Available This work investigates the formation mechanisms of chips in orthogonal cutting of mild steel and the transformation conditions between various morphology chips. It is supposed that the modeling material follows the Johnson-Cook constitutive model. In orthogonal cutting process, both the plastic flow and the instability behaviors of chip materials are caused by the plane strain loadings. Therefore, the general instability behaviors of materials in plane strain state are first analyzed with linear perturbation method and a universal instability criterion is established. Based on the analytical results, the formation mechanisms of chips and the transformation conditions between continuous and serrated chips are further studied by instability phase diagram method. The results show that the chip formation strongly depends on the intensity ratios between shear and normal stresses. The ratios of dissipative rates of plastic work done by compression and shear stresses govern the transformation from continuous to serrated chips. These results are verified by the numerical simulations on the orthogonal cutting process.

  7. Thermal-Aware Scheduling for Future Chip Multiprocessors

    Directory of Open Access Journals (Sweden)

    Pedro Trancoso

    2007-04-01

    Full Text Available The increased complexity and operating frequency in current single chip microprocessors is resulting in a decrease in the performance improvements. Consequently, major manufacturers offer chip multiprocessor (CMP architectures in order to keep up with the expected performance gains. This architecture is successfully being introduced in many markets including that of the embedded systems. Nevertheless, the integration of several cores onto the same chip may lead to increased heat dissipation and consequently additional costs for cooling, higher power consumption, decrease of the reliability, and thermal-induced performance loss, among others. In this paper, we analyze the evolution of the thermal issues for the future chip multiprocessor architectures and show that as the number of on-chip cores increases, the thermal-induced problems will worsen. In addition, we present several scenarios that result in excessive thermal stress to the CMP chip or significant performance loss. In order to minimize or even eliminate these problems, we propose thermal-aware scheduler (TAS algorithms. When assigning processes to cores, TAS takes their temperature and cooling ability into account in order to avoid thermal stress and at the same time improve the performance. Experimental results have shown that a TAS algorithm that considers also the temperatures of neighboring cores is able to significantly reduce the temperature-induced performance loss while at the same time, decrease the chip's temperature across many different operation and configuration scenarios.

  8. Reviewing ChIPS, The Chandra Imaging and Plotting System

    Science.gov (United States)

    Miller, J.; Burke, D. J.; Evans, I. N.; Evans, J. D.; McLaughlin, W.

    2015-09-01

    The Chandra Imaging and Plotting System (ChIPS) is a 2D plotting system designed to allow users to easily create, manipulate, and produce publication quality visualizations. ChIPS has a simple but very powerful interactive interface that allows users to dynamically modify the contents and layout of their plots quickly and efficiently, with the results of any changes being immediately visible. ChIPS allows users to construct their plots fully interactively, and then save the final plot commands as a Python script. This bypasses the need to iteratively edit and rerun the script when developing the plot. Features such as undo and redo commands allow users to easily step backwards and forwards through previous commands, while the ability so save ChIPS sessions in a platform-independent state file allows the session to be restored at any time, even on another machine. Because ChIPS offers a Python interface, users can analyze their data using the broad array of modules offered in Python, and visualize the information in ChIPS at the same time. In this paper we explore the design decisions behind the development of ChIPS and some of the lessons learned along the way.

  9. Applications of artificial neural network chips

    International Nuclear Information System (INIS)

    In a collaboration between CERN and Royal Institute of Technology Stockholm a so called Asynchronous Transfer Mode (ATM) test setup was developed. The main goal of the task was the experimental verification of the harware design principles and methods, partly the application of the test setup for testing the neural network controlled self-routing, asynchronous event-building ATM networks. We took part in the first implementation of the IBM Zero Instruction Set Computer (ZISC036)[2] on a PC-486 ISA-bus card. This chip has been designed for cost-effective recognition and classification in real time. After building the PC interface card and testing the main functions of the built-in logic a code for character recognition was developed for comparing its performance to other RBF-type methods. The results show that the ZISC036 is performing quite well. The most attractive feature of the chip is the speed: if it is operated at 20 MHz, 64 component the evaluation is ready in 0.5 μ sec. (K.A.) 2 refs.; 1 fig

  10. Readout Architecture for Hybrid Pixel Readout Chips

    CERN Document Server

    AUTHOR|(SzGeCERN)694170; Westerlund, Tomi; Wyllie, Ken

    The original contribution of this thesis to knowledge are novel digital readout architectures for hybrid pixel readout chips. The thesis presents asynchronous bus-based architecture, a data-node based column architecture and a network-based pixel matrix architecture for data transportation. It is shown that the data-node architecture achieves readout efficiency 99 % with half the output rate as a bus-based system. The network-based solution avoids ``broken'' columns due to some manufacturing errors, and it distributes internal data traffic more evenly across the pixel matrix than column-based architectures. An improvement of $>$ 10 % to the efficiency is achieved with uniform and non-uniform hit occupancies. Architectural design has been done using transaction level modeling ($TLM$) and sequential high-level design techniques for reducing the design and simulation time. It has been possible to simulate tens of column and full chip architectures using the high-level techniques. A decrease of $>$ 10 in run-time...

  11. Optical continuum generation on a silicon chip

    Science.gov (United States)

    Jalali, Bahram; Boyraz, Ozdal; Koonath, Prakash; Raghunathan, Varun; Indukuri, Tejaswi; Dimitropoulos, Dimitri

    2005-08-01

    Although the Raman effect is nearly two orders of magnitude stronger than the electronic Kerr nonlinearity in silicon, under pulsed operation regime where the pulse width is shorter than the phonon response time, Raman effect is suppressed and Kerr nonlinearity dominates. Continuum generation, made possible by the non-resonant Kerr nonlinearity, offers a technologically and economically appealing path to WDM communication at the inter-chip or intra-chip levels. We have studied this phenomenon experimentally and theoretically. Experimentally, a 2 fold spectral broadening is obtained by launching ~4ps optical pulses with 2.2GW/cm2 peak power into a conventional silicon waveguide. Theoretical calculations, that include the effect of two-photon-absorption, free carrier absorption and refractive index change indicate that up to >30 times spectral broadening is achievable in an optimized device. The broadening is due to self phase modulation and saturates due to two photon absorption. Additionally, we find that free carrier dynamics also contributes to the spectral broadening and cause the overall spectrum to be asymmetric with respect to the pump wavelength.

  12. On-chip p-MOSFET dosimetry

    International Nuclear Information System (INIS)

    In this work, a p-FET dosimeter is developed under the constraint that the dosimeter be useful in predicting the radiation dose of an IC fabricated with a non-radiation hardened 1.2-μm CMOS process. On-chip p-FETs were developed to monitor the radiation dose of n-well CMOS ICs by monitoring threshold voltage shifts due to radiation induced oxide and interface charge. The design employs closed geometry FETs and a zero-biased n-well to eliminate leakage currents. The FETs are operated using a constant current chosen to greatly reduce the FET's temperature sensitivity. The dose sensitivity of these p-FETs is about -2.6 mV/krad(Si) and the off-chip instrumentation resolves about 400 rad(Si)/bit. When operated with a current at the temperature-independent point, it was discovered that the pre-irradiation output voltage is about -1.5 V which depends only on design-independent silicon material parameters. The temperature sensitivity is less than 63 μV/C over a 70 C temperature range centered about the temperature insensitive point

  13. Long-Range Dependence and On-chip Processor traffic

    OpenAIRE

    Scherrer, Antoine; Fraboulet, Antoine; Risset, Tanguy

    2009-01-01

    Long-range dependence is a property of stochastic processes that has an important impact on network performance, especially on the buffer usage in routers. We analyze the presence of long-range dependence in on-chip processor traffic and we study the impact of long-range dependence on networks-on-chip. long-range dependence in communication traces of processor ips at the cycle-accurate level. We also study the impact of long-range dependence on a real network-on-chip using the SocLib simulati...

  14. On-chip solar battery structure for CMOS LSI

    OpenAIRE

    Arima, Yutaka; Ehara, Masaya

    2006-01-01

    A built-in method of on-chip solar battery in a CMOS LSI is proposed. The proposed solar battery can be formed using conventional CMOS process technology. It can generate a high voltage of 0.6-0.83 V by a series connection structure of two types of p-n junction diodes formed with the CMOS circuit simultaneously on the LSI chip. The generated voltage is sufficient to drive the conventional CMOS circuit without modi. cation. The test chip was produced experimentally using conventional 0.35 mu m...

  15. MOISTURE HUMIDITY EQUILIBRIUM OF WOOD CHIPS FROM ENERGETIC CROPS

    Directory of Open Access Journals (Sweden)

    Jan Barwicki

    2008-09-01

    Full Text Available Processes occurring during storage of wood chips for energetic or furniture industry purposes were presented. As a result of carried out investigations, dependences of temperature and relative humidity changes of surrounding air were shown. Modified Henderson equation can be utilized for computer simulation of storing and drying processes concerning wood chips for energetic and furniture industry purposes. It reflects also obtained results from experiments carried out with above mentioned material. Using computer simulation program we can examine different wood chips storing conditions to avoid overheating and loss problems.

  16. Energy model of network-on-chip and a bus

    OpenAIRE

    Wolkotte, Pascal T.; Smit, Gerard J.M.; Kavaldjiev, Nikolay; Becker, Jens E.; Becker, Jurgen

    2005-01-01

    A Network-on-Chip (NoC) is an energy-efficient onchip communication architecture for Multi-Processor Systemon- Chip (MPSoC) architectures. In earlier papers we proposed two Network-on-Chip architectures based on packet-switching and circuit-switching. In this paper we derive an energy model for both NoC architectures to predict their energy consumption per transported bit. Both architectures are also compared with a traditional bus architecture. The energy model is primarily needed to find a ...

  17. Energy Model of Networks-on-Chip and a Bus

    OpenAIRE

    Wolkotte, Pascal T.; Smit, Gerard J.M.; Kavaldjiev, Nikolay; Becker, Jens E.; Becker, Jürgen

    2005-01-01

    A Network-on-Chip (NoC) is an energy-efficient onchip communication architecture for Multi-Processor Systemon-Chip (MPSoC) architectures. In earlier papers we proposed two Network-on-Chip architectures based on packet-switching and circuit-switching. In this paper we derive an energy model for both NoC architectures to predict their energy consumption per transported bit. Both architectures are also compared with a traditional bus architecture. The energy model is primarily needed to find a n...

  18. Test of an ME Chip Based on FPGAs

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The characteristic of FPGA, motion estimation(ME) and the full search block matching arithmetic were introduced, it analyses the collectivity configuration of basic working flow in ME.Based on FPGA, the study concentrates on the control, computing and test part of ME chip implementation.In the end PCB of ME chip is designed and completed.ME is an important link of MPEG standard on picture compression, whose characteristics is its huge amount of data and computing task.So people often use special chip to meet the requirement, but there is still not such production in China at present.

  19. Lab-on-a-chip techniques, circuits, and biomedical applications

    CERN Document Server

    Ghallab, Yehya H

    2010-01-01

    Here's a groundbreaking book that introduces and discusses the important aspects of lab-on-a-chip, including the practical techniques, circuits, microsystems, and key applications in the biomedical, biology, and life science fields. Moreover, this volume covers ongoing research in lab-on-a-chip integration and electric field imaging. Presented in a clear and logical manner, the book provides you with the fundamental underpinnings of lab-on-a-chip, presents practical results, and brings you up to date with state-of-the-art research in the field. This unique resource is supported with over 160 i

  20. Electrochemical Migration on Electronic Chip Resistors in Chloride Environments

    DEFF Research Database (Denmark)

    Minzari, Daniel; Jellesen, Morten Stendahl; Møller, Per;

    2009-01-01

    Electrochemical migration behavior of end terminals on ceramic chip resistors (CCRs) was studied using a novel experimental setup in varying sodium chloride concentrations from 0 to 1000 ppm. The chip resistor used for the investigation was 10-kΩ CCR size 0805 with end terminals made of 97Sn3Pb...... alloy. Anodic polarization behavior of the electrode materials was investigated using a microelectrochemical setup. Material makeup of the chip resistor was investigated using scanning electron microscopy (SEM)/energy dispersive spectroscopy and focused-ion-beam SEM. Results showed that the dissolution...

  1. On-chip integrated lasers for biophotonic applications

    DEFF Research Database (Denmark)

    Mappes, Timo; Wienhold, Tobias; Bog, Uwe;

    Meeting the need of biomedical users, we develop disposable Lab-on-a-Chip systems based on commercially available polymers. We are combining passive microfluidics with active optical elements on-chip by integrating multiple solid-state and liquid-core lasers. While covering a wide range of laser...... emission wavelengths, the chips have the size of microscope cover slips and use optical and fluidic interconnects only. Here, we present our latest realizations of integrated optofluidic lasers using whispering gallery mode or distributed feedback laser cavities....

  2. Organ-on-a-Chip: New Platform for Biological Analysis.

    Science.gov (United States)

    An, Fan; Qu, Yueyang; Liu, Xianming; Zhong, Runtao; Luo, Yong

    2015-01-01

    Direct detection and analysis of biomolecules and cells in physiological microenvironment is urgently needed for fast evaluation of biology and pharmacy. The past several years have witnessed remarkable development opportunities in vitro organs and tissues models with multiple functions based on microfluidic devices, termed as "organ-on-a-chip". Briefly speaking, it is a promising technology in rebuilding physiological functions of tissues and organs, featuring mammalian cell co-culture and artificial microenvironment created by microchannel networks. In this review, we summarized the advances in studies of heart-, vessel-, liver-, neuron-, kidney- and Multi-organs-on-a-chip, and discussed some noteworthy potential on-chip detection schemes. PMID:26640364

  3. Memory conserving speech synthesis DSP chip; Sho memory onsei gosei DSP chip

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    which can be incorporated into a system having large restriction in terms of hardware. The system was incorporated successfully into a digital signal processor (DSP) chip for an answering phone. Reduction in speech elements, compression of an element dictionary, and simplification of synthesis processing have made the speech synthesizing part including the element dictionary as very compact as about 40 K bytes. The speech call-out function automatically gives accents on names registered in an address book with Katakana characters, converts them into synthesized sound and reads them out. The DSP chip is mounted on answering phone sets with number display, and has been put on sale since August 1998. (translated by NEDO)

  4. On-Chip Bondwire Magnetics with Ferrite-Epoxy Glob Coating for Power Systems on Chip

    Directory of Open Access Journals (Sweden)

    Jian Lu

    2008-01-01

    Full Text Available A novel concept of on-chip bondwire inductors and transformers with ferrite epoxy glob coating is proposed to offer a cost effective approach realizing power systems on chip (SOC. We have investigated the concept both experimentally and with finite element modeling. A Q factor of 30–40 is experimentally demonstrated for the bondwire inductors which represents an improvement by a factor of 3–30 over the state-of-the-art MEMS micromachined inductors. Transformer parameters including self- and mutual inductance and coupling factors are extracted from both modeled and measured S-parameters. More importantly, the bondwire magnetic components can be easily integrated into SOC manufacturing processes with minimal changes and open enormous possibilities for realizing cost-effective, high-current, high-efficiency power SOCs.

  5. On-Chip Test Infrastructure Design for Optimal Multi-Site Testing of System Chips

    CERN Document Server

    Goel, Sandeep Kumar

    2011-01-01

    Multi-site testing is a popular and effective way to increase test throughput and reduce test costs. We present a test throughput model, in which we focus on wafer testing, and consider parameters like test time, index time, abort-on-fail, and contact yield. Conventional multi-site testing requires sufficient ATE resources, such as ATE channels, to allow to test multiple SOCs in parallel. In this paper, we design and optimize on-chip DfT, in order to maximize the test throughput for a given SOC and ATE. The on-chip DfT consists of an E-RPCT wrapper, and, for modular SOCs, module wrappers and TAMs. We present experimental results for a Philips SOC and several ITC'02 SOC Test Benchmarks.

  6. FY1995 trial production of brain functional chip; 1995 nendo no kino shuseki chip no shisaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The present computer system will run on a program which is prepared in advance. On the other hand, the human brain can acquire some processes from learning with experiments. It would be very useful us human nature, if these learning process should be build up artificially. Our aim is to reveal basic self-acquiring mechanism of information and its processes of the brain, and preliminary research, including theoretical problems, for building up specialized processor chip. Many research on the brain have been held at the views of scientifically and medically. However; we focused on the principle brain learning process itself. The results of the research was directly realized on a specialized processor chip tuned for high-speed simulation of neural network. We could pointed out some problems on the present brain type processor, and discussed about basic technique for implementation of the next age brain type processor and theories. (NEDO)

  7. Design and characterization of an image acquisition system and its optomechanical module for chip defects inspection on chip sorters

    Science.gov (United States)

    Chen, Ming-Fu; Huang, Po-Hsuan; Chen, Yung-Hsiang; Cheng, Yu-Cheng

    2011-08-01

    Chip sorter is one of packaging facilities in chip manufactory. Defects will occur for a few of chips during manufacturing processes. If the size of chip defects is larger than a criterion of impacting chip quality, these flawed chips have to be detected and removed. Defects inspection system is usually developed with frame CCD imagers. There're some drawbacks for this system, such as mechanism of pause type for image acquisition, complicated acquisition control, easy damage for moving components, etc. And acquired images per chip have to be processed in radiometry and geometry and then pieced together before inspection. These processes impact the accuracy and efficiency of defects inspection. So approaches of image acquisition system and its opto-mechanical module will be critical for inspection system. In this article, design and characterization of a new image acquisition system and its opto-mechanical module are presented. Defects with size of greater than 15μm have to be inspected. Inspection performance shall be greater than 0.6 m/sec. Thus image acquisition system shall have the characteristics of having (1) the resolution of 5μm and 10μm for optical lens and linear CCD imager respectively; (2) the lens magnification of 2; (3) the line rate of greater than 120 kHz for imager output. The design of structure and outlines for new system and module are also described in this work. Proposed system has advantages of such as transporting chips in constant speed to acquire images, using one image only per chip for inspection, no image-mosaic process, simplifying the control of image acquisition. And the inspection efficiency and accuracy will be substantially improved.

  8. A novel optical network on chip design for future generation of multiprocessors system on chip

    OpenAIRE

    M. Channoufi; P. Lecoy; S. Le Beux; Attia, R; Delacressonniere, B

    2013-01-01

    The paper presents a novel Optical Network on Chip (ONoC) relying on the multi-level optical layer design paradigm and called “OMNoC”. The proposed ONoC relies on multi-level microring resonator allowing efficient light coupling between superposed waveguides. Such microring resonator avoids using waveguide crossing, which contribute to reduce propagation losses. Preliminary experimental results demonstrate the potential of multi-level optical layer for reducing power consumption and increasin...

  9. An Evaluation of an Integrated On-Chip/Off-Chip Network for High-Performance Reconfigurable Computing

    OpenAIRE

    Kritikos, William V.; Shanyuan Gao; Andrew G. Schmidt; Ron Sass

    2012-01-01

    As the number of cores per discrete integrated circuit (IC) device grows, the importance of the network on chip (NoC) increases. However, the body of research in this area has focused on discrete IC devices alone which may or may not serve the high-performance computing community which needs to assemble many of these devices into very large scale, parallel computing machines. This paper describes an integrated on-chip/off-chip network that has been implemented on an all-FPGA computing cluster...

  10. An Optical Inspection System Development for Defects on Multi-surfaces of Chips

    Directory of Open Access Journals (Sweden)

    Chen Ming-Fu

    2016-01-01

    Full Text Available We proposed a new architecture with multiple pick and place heads to suck inspected chips and to be moved synchronously for acquiring the images of different surfaces on different chips at their corresponding acquisition stations. The computation loading of defect inspection for each chip also can be distributed because of sequential image acquisition. Considering the different computing loading of 6 surfaces of a chip, image acquisition for the front and back sides of chips is allocated at the first and second stations, and then 4 edge sides of chips. The modification and calibration of position and orientation for each opto-mechanical device will be simpler and easier when the characteristics of inspected chips changed. Thus system can accomplish the inspection for 6 surfaces of each chip and determine its quality in real-time before that chip is put onto target wafer. Developed inspection system has advantages and contributions of real-time inspection with high throughput during chip sorting process, and easily adjustment and calibration for all opto-mechanical devices to inspectdifferent types of chips. The first phase of development was accomplished for an AOI system to inspect defects on 5 surfaces of chips. System has been integrated in customer’s chip sorter for testing. The inspecting accuracy for chip backside is better than 95%.

  11. Novel High Pressure Pump-on-a-Chip Technology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — HJ Science & Technology, Inc. proposes to develop a novel high pressure "pump-on-a-chip" (HPPOC) technology capable of generating high pressure and flow rate on...

  12. Experiment list: SRX386203 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available body=TAL1 - Santa Cruz Biotechnology sc-12984 http://dbarchive.biosciencedbc.jp/k...ell type=CD34+ HSPC-derived proerythroblasts || tissue=bone marrow || developmental stage=adult || chip anti

  13. Chip-level three-dimensional assembling of microsystems

    Science.gov (United States)

    Toshiyoshi, Hiroshi; Mita, Yoshio; Ogawa, Minoru; Fujita, Hiroyuki

    1999-03-01

    We propose a new method of assembling 3D microsystems by means of chip level electrical interconnection. Silicon dies are flip-chipped out of a silicon wafer by using ICP-RIE instead of a dicing saw. Fringes of the chips are patterned into pin-shapes so that they can be vertically inserted into the micro motherboard for electrical and physical connection. The pins are coated with Cr-Au, and the contact pads are electroplated with Cu for low contact resistance. the pins are tapered in width, and assembling was easily done by manual positing under the optical binocular microscope. This technique is a break through to the hybrid integration of various kinds of micro chips independent of materials or fabrication compatibility.

  14. Power and Thermal Management of System-on-Chip

    DEFF Research Database (Denmark)

    Liu, Wei

    , are necessary at the chip design level. In this work, we investigate the power and thermal management of System-on- Chips (SoCs). Thermal analysis is performed in a SPICE simulation approach based on the electrical-thermal analogy. We investigate the impact of inter- connects on heat distribution......With greater integration of VLSI circuits, power consumption and power density have increased dramatically resulting in high chip temperatures and presenting a heat removal challenge. To effectively limit the high temperature inside a chip, thermal specific approaches, besides low power techniques...... of temperature reduction, timing and area overhead to the general method, which enlarges the circuit area uniformly. A case study analyzes the design of Floating Point Units (FPU) from an energy and a thermal perspective. For the division operation, we compare different implementations and illustrate the impact...

  15. Experiment list: SRX271847 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ell type=Tonsillar naive B cells || treatment=NA || chip antibody=none || purification=Cells purified from normal fresh human tonsill...ectomy specimens by magnetic bead cell separation based on the expression the pheno

  16. Experiment list: SRX271845 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ll type=Tonsillar naive B cells || treatment=NA || chip antibody=none || purification=Cells purified from normal fresh human tonsille...ctomy specimens by magnetic bead cell separation based on the expression the phenot

  17. Experiment list: SRX1091820 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available -Seq source_name=Human myeloma cell line || cell line=Delta47 || chip antibody=First, IP with custom mouse monoclonal... BORIS Ab, next IP with custom mouse monoclonal CTCF http://dbarchive.bi

  18. Experiment list: SRX150262 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available alance, and learn motor skills. 26472027,92.7,6.9,186 GSM939576: ChIP of MNase mononucleosome selected cereb... cerebellar nuclei. Its function is to coordinate voluntary movements, maintain b

  19. Experiment list: SRX143851 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available lance, and learn motor skills. 57796523,71.5,23.1,31516 GSM918759: LICR ChipSeq Cerebellum CTCF adult-8wks s...cerebellar nuclei. Its function is to coordinate voluntary movements, maintain ba

  20. Experiment list: SRX143608 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Califonia Institute of Technology || datatype=ChipSeq || datatype description=Ch...t 60hr source_name=C2C12 || biomaterial_provider=Barbara Wold lab || lab=Caltech-m || lab description=Wold -

  1. Experiment list: SRX142531 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available r source_name=C2C12 || biomaterial_provider=Barbara Wold lab || lab=Caltech-m || lab description=Wold - Califonia Institute of Techno...logy || datatype=ChipSeq || datatype description=Chromat

  2. Experiment list: SRX142522 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Califonia Institute of Technology || datatype=ChipSeq || datatype description=Ch...t 60hr source_name=C2C12 || biomaterial_provider=Barbara Wold lab || lab=Caltech-m || lab description=Wold -

  3. On-Chip Network Design Automation with Source Routing Switches

    Institute of Scientific and Technical Information of China (English)

    MA Liwei; SUN Yihe

    2007-01-01

    Network-on-chip (NoC) is a new design paradigm for system-on-chip intraconnections in the billion-transistor era. Application specific on-chip network design is essential for NoC success in this new era.This paper presents a class of source routing switch that can be used to efficiently form arbitrary network topologies and that can be optimized for various applications. Hardware description language versions of the networks can be generated automatically for simulations and for syntheses. A series of switches and networks has been configured with their performances including latency, delay, area, and power, and analyzed theoretically and experimentally. The results show that this NoC architecture provides a large design space for application specific on-chip network designs.

  4. ANALYSIS OF CHIP FORMATION DURING HARD TURNING THROUGH ACOUSTIC EMISSION

    Directory of Open Access Journals (Sweden)

    Miroslav Neslušan

    2012-01-01

    Full Text Available The paper deals with analysis of chip formation and related aspects of the chip formation during turning hardened steel 100Cr6. The paper draws a comparison of some aspects of the chip formation between turning annealed and hardened roll bearing steel. The results of the analysis show that there is the formation of a segmented chip in the case of hard turning. Frequency of segmentation is very high. A conventional piezoelectric dynamometer limits the frequency response to about 3.5 kHz. On the other hand, the frequency of process fluctuation may by obtained by using accelerometers or acoustic emission. This paper reports about the dynamic character of cutting process when hard turning and correlation among the calculated segmentation frequencies and the experimental analysis.

  5. Experiment list: SRX067387 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ription=epidermal keratinocytes 35409658,46.4,13.0,46459 GSM733636: Bernstein NHEK CTCF source_name=NHEK || ...biomaterial_provider=Lonza || lab=Broad || lab description=Bernstein - Broad Institute || datatype=ChipSeq |

  6. Can Increases in CHIP Copayments Reduce Program Exp..

    Data.gov (United States)

    U.S. Department of Health & Human Services — According to the article, Can increases in CHIP copayments reduce program expenditures on prescription drugs in Volume 4, Issue 2, of Medicare and Medicaid Research...

  7. Experiment list: SRX333571 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available duction || genotype/variation=MBD3flox/- mouse Embryonic Fibroblast Cells (MEF) transgenic for DOX inducible OSKM reprogramming... || stage in reprogramming=4 days after DOX induction || chip

  8. Experiment list: SRX333580 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e/variation=MBD3flox/- mouse Embryonic Fibroblast Cells (MEF) transgenic for DOX inducible OSKM reprogramming || stage in reprogrammi...ng=iPSC || chip antibody=none http://dbarchive.bioscienc

  9. Experiment list: SRX500852 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available cell type=Embryonic Fibroblast Cells (MEF) || genotype/variation=MBD3+/+ transgenic for DOX inducible OSKM reprogramming... || stage in reprogramming=8 days after DOX induction || chip antibod

  10. Experiment list: SRX333554 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available genotype/variation=MBD3+/+ mouse Embryonic Fibroblast Cells (MEF) transgenic for DOX inducible OSKM reprogramming || stage in reprogr...amming=8 days after DOX induction || chip antibody=none

  11. Experiment list: SRX950703 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available type/variation=MBD3+/+ mouse Embryonic Fibroblast Cells (MEF) transgenic for DOX inducible OSKM reprogramming || stage in reprogrammi...ng=4 days after DOX induction || chip antibody=Oct4 (sc5

  12. Benchmarking the True Random Number Generator of TPM Chips

    CERN Document Server

    Suciu, Alin

    2010-01-01

    A TPM (trusted platform module) is a chip present mostly on newer motherboards, and its primary function is to create, store and work with cryptographic keys. This dedicated chip can serve to authenticate other devices or to protect encryption keys used by various software applications. Among other features, it comes with a True Random Number Generator (TRNG) that can be used for cryptographic purposes. This random number generator consists of a state machine that mixes unpredictable data with the output of a one way hash function. According the specification it can be a good source of unpredictable random numbers even without having to require a genuine source of hardware entropy. However the specification recommends collecting entropy from any internal sources available such as clock jitter or thermal noise in the chip itself, a feature that was implemented by most manufacturers. This paper will benchmark the random number generator of several TPM chips from two perspectives: the quality of the random bit s...

  13. Cascaded VLSI Chips Help Neural Network To Learn

    Science.gov (United States)

    Duong, Tuan A.; Daud, Taher; Thakoor, Anilkumar P.

    1993-01-01

    Cascading provides 12-bit resolution needed for learning. Using conventional silicon chip fabrication technology of VLSI, fully connected architecture consisting of 32 wide-range, variable gain, sigmoidal neurons along one diagonal and 7-bit resolution, electrically programmable, synaptic 32 x 31 weight matrix implemented on neuron-synapse chip. To increase weight nominally from 7 to 13 bits, synapses on chip individually cascaded with respective synapses on another 32 x 32 matrix chip with 7-bit resolution synapses only (without neurons). Cascade correlation algorithm varies number of layers effectively connected into network; adds hidden layers one at a time during learning process in such way as to optimize overall number of neurons and complexity and configuration of network.

  14. Crosstalk in modern on-chip interconnects a FDTD approach

    CERN Document Server

    Kaushik, B K; Patnaik, Amalendu

    2016-01-01

    The book provides accurate FDTD models for on-chip interconnects, covering most recent advancements in materials and design. Furthermore, depending on the geometry and physical configurations, different electrical equivalent models for CNT and GNR based interconnects are presented. Based on the electrical equivalent models the performance comparison among the Cu, CNT and GNR-based interconnects are also discussed in the book. The proposed models are validated with the HSPICE simulations. The book introduces the current research scenario in the modeling of on-chip interconnects. It presents the structure, properties, and characteristics of graphene based on-chip interconnects and the FDTD modeling of Cu based on-chip interconnects. The model considers the non-linear effects of CMOS driver as well as the transmission line effects of interconnect line that includes coupling capacitance and mutual inductance effects. In a more realistic manner, the proposed model includes the effect of width-dependent MFP of the ...

  15. Polymer Flip Chips with Extreme Temperature Stability in Space Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the proposed SBIR Phase I program is to develop highly thermally and electrically conductive nanocomposites for space-based flip chips for...

  16. Experiment list: SRX998283 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nucleus tissue || tissue=Caudate nucleus || gender=female || age=68 || Cause of death=Myocardial decompens...ation with sepsis || postmortem delay=4.2 hrs || experiment type=ChIP-Seq || chip a

  17. Experiment list: SRX1521230 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available H3K27ac polyclonal Ref: Active motif 39133 http://dbarchive.biosciencedbc.jp/kyus...HeLa cells || cell line=HeLa cells || treatment=Paraformaldehyde fixation (1%, 30 minutes) || chip antibody=

  18. Experiment list: SRX1521238 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available La cells || cell line=HeLa cells || treatment=Paraformaldehyde fixation (1%, 30 minutes) || chip antibody=H3K4me3 polyclonal Ref: Act...ive motif 39159 http://dbarchive.biosciencedbc.jp/kyushu

  19. Experiment list: SRX1521232 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available H3K4me3 monoclonal Ref: Active motif 61379 http://dbarchive.biosciencedbc.jp/kyus...HeLa cells || cell line=HeLa cells || treatment=Paraformaldehyde fixation (1%, 30 minutes) || chip antibody=

  20. Thermal properties of AlN-based atom chips

    CERN Document Server

    Armijo, Julien; Bouchoule, Isabelle

    2009-01-01

    We have studied the thermal properties of atom chips consisting o high thermal conductivity Aluminum Nitride (AlN) substrates on which gold microwires are directly deposited. We have measured the heating of wires of several widths and with different thermal couplings to the copper mount holding the chip. The results are in good agreement with a theoretical model where the copper mount is treated as a heat sink and the thermal interface resistance between the wire and the substrate is vanishing. We give analytical formulas describing the different transient heating regimes and the steady state. We identify criteria to optimize the design of a chip as well as the maximal currents $I_c$ that can be fed in the wires. For a 600$\\mu$m thick-chip glued on a copper block with Epotek H77, we find $I_c=16$A for a 3$\\mu$m high, 200$\\mu$m wide-wire.

  1. Experiment list: SRX425486 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ologies, Inc.) http://dbarchive.biosciencedbc.jp/kyushu-...28 || cell type=mineralizing osteoblast || passages=28-31 || strain=C57BL/6 || chip antibody=Runx2 antibody (M70, Santa Cruz Biotechn

  2. Experiment list: SRX020951 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ologies, 06-942) http://dbarchive.biosciencedbc.jp/kyush... lysine 9 || cell line=3T3-L1 || developmental stage=10 days after inducing differentiation || chip antibody=H3K9ac (Upstate Biotechn

  3. Experiment list: SRX503337 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ame=Human Burkitt lymphoma || cell type=Human Burkitt lymphoma B cells || cell line=BJAB || chip antibody=LANA (Advanced Biotechnolog...ies, 13-210-100) http://dbarchive.biosciencedbc.jp/kyush

  4. Gain spectroscopy of a type-II VECSEL chip

    CERN Document Server

    Lammers, Christian; Berger, Christian; Möller, Christoph; Fuchs, Christian; Perez, Antje Ruiz; Rahimi-Iman, Arash; Hader, Jörg; Moloney, Jerome; Stolz, Wolfgang; Koch, Stephan W; Koch, Martin

    2016-01-01

    Using optical pump-white light probe spectroscopy the gain dynamics is investigated for a VECSEL chip which is based on a type-II heterostructure. The active region the chip consists of a GaAs/(GaIn)As/Ga(AsSb)/(GaIn)As/GaAs multiple quantum well. For this structure, a fully microscopic theory predicts a modal room temperature gain at a wavelength of 1170 nm, which is confirmed by experimental spectra. The results show a gain buildup on the type-II chip which is delayed relative to that of a type-I chip. This slower gain dynamics is attributed to a diminished cooling rate arising from reduced electron-hole scattering.

  5. Development of gold based solder candidates for flip chip assembly

    DEFF Research Database (Denmark)

    Chidambaram, Vivek; Hald, John; Hattel, Jesper Henri

    2009-01-01

    Flip chip technology is now rapidly replacing the traditional wire bonding interconnection technology in the first level packaging applications due to the miniaturization drive in the microelectronics industry. Flip chip assembly currently involves the use of high lead containing solders...... for interconnecting the chip to a carrier in certain applications due to the unique properties of lead. Despite of all the beneficial attributes of lead, its potential environmental impact when the products are discarded to land fills has resulted in various legislatives to eliminate lead from the electronic products...... based on its notorious legacy as a major health hazard across the spectrum of human generations and cultures. Flip chip assembly is also now increasingly being used for the high-performance (H-P) systems. These H-P systems perform mission-critical operations and are expected to experience virtually...

  6. Method for forming consumable electrodes from metallic chip scraps

    Science.gov (United States)

    Girshov, Vladimir Leonidovich; Podpalkin, Arcady Munjyvich; Treschevskiy, Arnold Nikolayevich; Abramov, Alexey Alexandrovich

    2005-10-11

    The method relates to metallurgical recycling of waste products, preferably titanium alloys chips scrap. Accordingly after crushing and cleaning, the chip scrap is subjected to vacuum-thermal degassing (VTD); the chip scrap is pressed into briquettes; the briquettes are placed into a mould allowing sufficient remaining space for the addition of molten metal alloy; the mould is pre-heated before filling with the molten metal alloy; the mould remaining space is filled with molten metal alloy. After cooling, the electrode is removed from the mould. The method provides a means for 100% use of chip scrap in producing consumable electrodes having increased mechanical strength and reduced interstitial impurities content leading to improved secondary cast alloys.

  7. Fault Tolerance Mechanism in Chip Many-Core Processors

    Institute of Scientific and Technical Information of China (English)

    ZHANG Lei; HAN Yinhe; LI Huawei; LI Xiaowei

    2007-01-01

    As semiconductor technology advances, there will be billions of transistors on a single chip. Chip many-core processors are emerging to take advantage of these greater transistor densities to deliver greater performance. Effective fault tolerance techniques are essential to improve the yield of such complex chips. In this paper, a core-level redundancy scheme called N+M is proposed to improve N-core processors'yield by providing M spare cores. In such architecture, topology is an important factor because it greatly affects the processors'performance. The concept of logical topology and a topology reconfiguration problem are introduced, which is able to transparently provide target topology with lowest performance degradation as the presence of faulty cores on-chip. A row rippling and column stealing (RRCS) algorithm is also proposed. Results show that PRCS can give solutions with average 13.8% degradation with negligible computing time.

  8. Experiment list: SRX395531 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available III antibody (gift from Jason Lieb) || strain=N2 http://dbarchive.biosciencedbc.j...ce_name=staged young adults (N2) || developmental stage=YA || tissue=whole animal || chip antibody=anti-Pol

  9. Experiment list: SRX245510 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available lation=Plasmablasts were induced by injecting 6-week old...| chip antibody manufacturer=Millipore || cell type=splenic Plasmablasts || strain=C57BL/6 || cell surface markers=CD138+ || cell iso

  10. Droplets actuating chip based on electrowetting-on-dielectric

    Institute of Scientific and Technical Information of China (English)

    WU Jiangang; YUE Ruifeng; ZENG Xuefeng; LIU Litian

    2007-01-01

    A droplet-based actuating chip by using the method of electrowetting-on-dielectric (EWOD)was developed to manipulate the microfluidics.Here,the actuation mechanism of the sandwiched-configuration EWOD chips was carefully studied,and the movement of droplets was numerically analyzed by using the computational fluidic software,CFD-ACE+.The fabrication of the chip,including a heavily phosphorus-doped poly-silicon micro-electrode array and a thermally grown SiO2 dielectric layer,was exploited to improve the chip stability and decrease the actuation voltage.In experiments,the transportation of a deionized droplet of about 0.5 μL is successfully achieved in air by applying the low voltage of 45 V.

  11. Experiment list: SRX306574 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available mesoderm|Description=lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epst...astoid cell line || population=YRI || ethnicity=Yoruba || country of origin=Nigeria || chip antibody=PolII (

  12. Experiment list: SRX306581 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available mesoderm|Description=B-lymphocyte, lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, t...l type=lymphoblastoid cell line || population=YRI || ethnicity=Yoruba || country of origin=Nigeria || chip a

  13. Experiment list: SRX306579 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available mesoderm|Description=lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, treatment: Epst...lastoid cell line || population=YRI || ethnicity=Yoruba || country of origin=Nigeria || chip antibody=PolII

  14. Experiment list: SRX306582 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available mesoderm|Description=B-lymphocyte, lymphoblastoid, International HapMap Project, Yoruba in Ibadan, Nigera, t...l type=lymphoblastoid cell line || population=YRI || ethnicity=Yoruba || country of origin=Nigeria || chip a

  15. Bier and Pastis, a pixel readout prototype chip for LHC

    CERN Document Server

    Berg, C; Bonzom, V; Delpierre, P A; Desch, Klaus; Fischer, P; Keil, M; Meuser, S; Raith, B A; Wermes, N

    2000-01-01

    The 12*63 pixel readout prototype chip Bieu&Pastis, designed to cope with the environment imposed on a pixel detector by high-energy proton-proton collisions as expected at the Large Hadron Collider (LHC), is described. The chip contains the full pixel cell functionality, but not yet the full peripheral architecture for data transfer and readout with LHC speed. Design considerations and lab tests to characterize the performance as well as some test beam results are described. (7 refs).

  16. Bier&Pastis, a pixel readout prototype chip for LHC

    Science.gov (United States)

    Berg, C.; Blanquart, L.; Bonzom, V.; Delpierre, P.; Desch, K.; Fischer, P.; Keil, M.; Meuser, S.; Raith, B.; Wermes, N.

    2000-01-01

    The 12×63 pixel readout prototype chip Bier&Pastis, designed to cope with the environment imposed on a pixel detector by high-energy proton-proton collisions as expected at the Large Hadron Collider (LHC), is described. The chip contains the full pixel cell functionality, but not yet the full peripheral architecture for data transfer and readout with LHC speed. Design considerations and lab tests to characterize the performance as well as some test beam results are described.

  17. Experiment list: SRX398296 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Colon|Tissue Diagnosis=Carcinoma 24543313,77.7,11.3,1072 GSM1296639: Colo741 WCE ChipSeq; Homo sapiens; ChIP...-Seq source_name=Colon Carcinoma || chip antibody=None || antibody catalog number=None WCE || cell line=Colo...741 || cell type=Colon Carcinoma http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/...SRX398296 hg19 Input control Input control Digestive tract COLO 741 Primary Tissue=

  18. Experiment list: SRX398298 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e Diagnosis=Adenocarcinoma 60079752,94.0,37.2,13687 GSM1296641: HT29 CDK8 ChipSeq; Homo sapiens; ChIP-Seq source_name=Colon Carcinoma...T29 || cell type=Colon Carcinoma http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/... || chip antibody=CDK8 || antibody catalog number=Santa Cruz SC-1521 || cell line=H

  19. Single-chip microprocessor that communicates directly using light

    Science.gov (United States)

    Sun, Chen; Wade, Mark T.; Lee, Yunsup; Orcutt, Jason S.; Alloatti, Luca; Georgas, Michael S.; Waterman, Andrew S.; Shainline, Jeffrey M.; Avizienis, Rimas R.; Lin, Sen; Moss, Benjamin R.; Kumar, Rajesh; Pavanello, Fabio; Atabaki, Amir H.; Cook, Henry M.; Ou, Albert J.; Leu, Jonathan C.; Chen, Yu-Hsin; Asanović, Krste; Ram, Rajeev J.; Popović, Miloš A.; Stojanović, Vladimir M.

    2015-12-01

    Data transport across short electrical wires is limited by both bandwidth and power density, which creates a performance bottleneck for semiconductor microchips in modern computer systems—from mobile phones to large-scale data centres. These limitations can be overcome by using optical communications based on chip-scale electronic-photonic systems enabled by silicon-based nanophotonic devices8. However, combining electronics and photonics on the same chip has proved challenging, owing to microchip manufacturing conflicts between electronics and photonics. Consequently, current electronic-photonic chips are limited to niche manufacturing processes and include only a few optical devices alongside simple circuits. Here we report an electronic-photonic system on a single chip integrating over 70 million transistors and 850 photonic components that work together to provide logic, memory, and interconnect functions. This system is a realization of a microprocessor that uses on-chip photonic devices to directly communicate with other chips using light. To integrate electronics and photonics at the scale of a microprocessor chip, we adopt a ‘zero-change’ approach to the integration of photonics. Instead of developing a custom process to enable the fabrication of photonics, which would complicate or eliminate the possibility of integration with state-of-the-art transistors at large scale and at high yield, we design optical devices using a standard microelectronics foundry process that is used for modern microprocessors. This demonstration could represent the beginning of an era of chip-scale electronic-photonic systems with the potential to transform computing system architectures, enabling more powerful computers, from network infrastructure to data centres and supercomputers.

  20. Experiment list: SRX796321 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available last|Lineage=primaryCells|Description=Mouse Embryonic Fibroblast 31665544,97.7,15.6,275 GSM1558591: HMGA2 Chip seq in MEF Hmga...L/6 || genotype/variation=Hmga2 Ko || chip antibody=HMGA2 (Santa cruz, cat. sc-30223, lot: F1407 ) http://db...SRX796321 mm9 TFs and others Hmga2 Embryonic fibroblast MEF Tissue=Embryonic Fibrob

  1. Experiment list: SRX190193 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available rce_name=HL-60 || biomaterial_provider=ATCC || datatype=ChipSeq || datatype description=Chromatin IP Sequencing || antibody antibody...description=Mouse monoclonal to RNA polymerase II CTD repeat YSPTSPS antibody... (4H8) - ChIP Grade. Antibody Target: POL2 || antibody targetdescription=This gene encod...es the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes || antibody... vendorname=abcam || antibody vendorid=ab5408 || controlid=SL

  2. Experiment list: SRX100529 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available aterial_provider=WiCell Research Institute || datatype=ChipSeq || datatype description=Chromatin IP Sequencing || antibody antibody...description=Mouse monoclonal to RNA polymerase II CTD repeat YSPTSPS antibody... (4H8) - ChIP Grade. Antibody Target: POL2 || antibody targetdescription=This gene encode...s the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes || antibody... vendorname=abcam || antibody vendorid=ab5408 || controlid=SL9

  3. Experiment list: SRX190259 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available e_name=H1-neurons || biomaterial_provider=CDI || datatype=ChipSeq || datatype description=Chromatin IP Sequencing || antibody antibod...ydescription=Mouse monoclonal to RNA polymerase II CTD repeat YSPTSPS antibody... (4H8) - ChIP Grade. Antibody Target: POL2 || antibody targetdescription=This gene enc...odes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes || antibody... vendorname=abcam || antibody vendorid=ab5408 || controlid=

  4. Experiment list: SRX100504 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available .1 source_name=U87 || biomaterial_provider=ATCC || datatype=ChipSeq || datatype description=Chromatin IP Sequencing || antibody antib...odydescription=Mouse monoclonal to RNA polymerase II CTD repeat YSPTSPS antibody... (4H8) - ChIP Grade. Antibody Target: POL2 || antibody targetdescription=This gene e...ncodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes || antibody... vendorname=abcam || antibody vendorid=ab5408 || controli

  5. Experiment list: SRX150535 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available t|Tissue Diagnosis=Fibrocystic Disease 69171580,86.8,43.7,20874 GSM935456: Harvard ChipSeq MCF10A-Er-Src 4OH...TAM 1uM 36hr Pol2 std source_name=MCF10A-Er-Src || biomaterial_provider=Struhl laboratory || lab=Harvard || ...lab description=Struhl - Harvard University || datatype=ChipSeq || datatype descr

  6. Experiment list: SRX150562 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available -Barr Virus 57294082,73.4,6.6,1909 GSM935483: Harvard ChipSeq GM12878 ZZZ3 std source_name=GM12878 || biomat...rd || lab description=Struhl - Harvard University || datatype=ChipSeq || datatype d...erial_provider=Coriell; http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM12878 || lab=Harva

  7. Experiment list: SRX150629 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available sue Diagnosis=Fibrocystic Disease 27949151,89.1,5.9,589 GSM935550: Harvard ChipSeq MCF10A-Er-Src EtOH 0.01pc...t 12hr Input std source_name=MCF10A-Er-Src || biomaterial_provider=Struhl laboratory || lab=Harvard || lab description=Struhl - Harva...rd University || datatype=ChipSeq || datatype descriptio

  8. Experiment list: SRX150494 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available n-Barr Virus 44912180,85.6,7.7,1806 GSM935415: Harvard ChipSeq GM12878 GCN5 std source_name=GM12878 || bioma...ard || lab description=Struhl - Harvard University || datatype=ChipSeq || datatype ...terial_provider=Coriell; http://ccr.coriell.org/Sections/Search/Search.aspx?PgId=165&q=GM12878 || lab=Harv

  9. Experiment list: SRX150667 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available t|Tissue Diagnosis=Fibrocystic Disease 69172664,86.5,35.3,28780 GSM935588: Harvard ChipSeq MCF10A-Er-Src EtO...H 0.01pct Pol2 std source_name=MCF10A-Er-Src || biomaterial_provider=Struhl laboratory || lab=Harvard || lab description=Struhl - Har...vard University || datatype=ChipSeq || datatype descript

  10. The GenoChip: a new tool for genetic anthropology.

    Science.gov (United States)

    Elhaik, Eran; Greenspan, Elliott; Staats, Sean; Krahn, Thomas; Tyler-Smith, Chris; Xue, Yali; Tofanelli, Sergio; Francalacci, Paolo; Cucca, Francesco; Pagani, Luca; Jin, Li; Li, Hui; Schurr, Theodore G; Greenspan, Bennett; Spencer Wells, R

    2013-01-01

    The Genographic Project is an international effort aimed at charting human migratory history. The project is nonprofit and nonmedical, and, through its Legacy Fund, supports locally led efforts to preserve indigenous and traditional cultures. Although the first phase of the project was focused on uniparentally inherited markers on the Y-chromosome and mitochondrial DNA (mtDNA), the current phase focuses on markers from across the entire genome to obtain a more complete understanding of human genetic variation. Although many commercial arrays exist for genome-wide single-nucleotide polymorphism (SNP) genotyping, they were designed for medical genetic studies and contain medically related markers that are inappropriate for global population genetic studies. GenoChip, the Genographic Project's new genotyping array, was designed to resolve these issues and enable higher resolution research into outstanding questions in genetic anthropology. The GenoChip includes ancestry informative markers obtained for over 450 human populations, an ancient human (Saqqaq), and two archaic hominins (Neanderthal and Denisovan) and was designed to identify all known Y-chromosome and mtDNA haplogroups. The chip was carefully vetted to avoid inclusion of medically relevant markers. To demonstrate its capabilities, we compared the FST distributions of GenoChip SNPs to those of two commercial arrays. Although all arrays yielded similarly shaped (inverse J) FST distributions, the GenoChip autosomal and X-chromosomal distributions had the highest mean FST, attesting to its ability to discern subpopulations. The chip performances are illustrated in a principal component analysis for 14 worldwide populations. In summary, the GenoChip is a dedicated genotyping platform for genetic anthropology. With an unprecedented number of approximately 12,000 Y-chromosomal and approximately 3,300 mtDNA SNPs and over 130,000 autosomal and X-chromosomal SNPs without any known health, medical, or phenotypic

  11. Signal processing for on-chip space division multiplexing

    DEFF Research Database (Denmark)

    Peucheret, Christophe; Ding, Yunhong; Xu, Jing;

    2015-01-01

    Our recent results on the demonstration of on-chip mode-division multiplexing are reviewed, with special emphasis on nonlinear all-optical signal processing. Mode-selective parametric processes are demonstrated in a silicon-on-insulator waveguide.......Our recent results on the demonstration of on-chip mode-division multiplexing are reviewed, with special emphasis on nonlinear all-optical signal processing. Mode-selective parametric processes are demonstrated in a silicon-on-insulator waveguide....

  12. Chip-Level Design for Digital Microfluidic Biochips

    Directory of Open Access Journals (Sweden)

    Shang Tsung Yu

    2014-11-01

    Full Text Available Recently, electrowetting-on-dielectric (EWOD chips have become the most popular actuator for droplet-based digital microfluidic biochips (DMFBs due to its high throughput, automatic control, and low cost. As the complexity of biochemical assays increases, powerful computer-aided-design (CAD tools are needed. This paper provides an overview of DMFBs and describes some important issues and problems in the chip-level design of DMFBs.

  13. Single-chip microprocessor that communicates directly using light.

    Science.gov (United States)

    Sun, Chen; Wade, Mark T; Lee, Yunsup; Orcutt, Jason S; Alloatti, Luca; Georgas, Michael S; Waterman, Andrew S; Shainline, Jeffrey M; Avizienis, Rimas R; Lin, Sen; Moss, Benjamin R; Kumar, Rajesh; Pavanello, Fabio; Atabaki, Amir H; Cook, Henry M; Ou, Albert J; Leu, Jonathan C; Chen, Yu-Hsin; Asanović, Krste; Ram, Rajeev J; Popović, Miloš A; Stojanović, Vladimir M

    2015-12-24

    Data transport across short electrical wires is limited by both bandwidth and power density, which creates a performance bottleneck for semiconductor microchips in modern computer systems--from mobile phones to large-scale data centres. These limitations can be overcome by using optical communications based on chip-scale electronic-photonic systems enabled by silicon-based nanophotonic devices. However, combining electronics and photonics on the same chip has proved challenging, owing to microchip manufacturing conflicts between electronics and photonics. Consequently, current electronic-photonic chips are limited to niche manufacturing processes and include only a few optical devices alongside simple circuits. Here we report an electronic-photonic system on a single chip integrating over 70 million transistors and 850 photonic components that work together to provide logic, memory, and interconnect functions. This system is a realization of a microprocessor that uses on-chip photonic devices to directly communicate with other chips using light. To integrate electronics and photonics at the scale of a microprocessor chip, we adopt a 'zero-change' approach to the integration of photonics. Instead of developing a custom process to enable the fabrication of photonics, which would complicate or eliminate the possibility of integration with state-of-the-art transistors at large scale and at high yield, we design optical devices using a standard microelectronics foundry process that is used for modern microprocessors. This demonstration could represent the beginning of an era of chip-scale electronic-photonic systems with the potential to transform computing system architectures, enabling more powerful computers, from network infrastructure to data centres and supercomputers. PMID:26701054

  14. Perancangan Dan Implementasi Pengendali PID DIgital Pada Komputer Chip Tunggal

    OpenAIRE

    Adnan, Adnan; Intan, Sari Areni

    2006-01-01

    Penelitian ini bertujuan untuk merancang sistem kendali PID digital yang diimplementaasikan pada sistem komputer chip tunggal. Sistem komputer chip tunggal yang diiigunakan adalah sistem DT51 low cost micro yang berbasis CPU Atmel AT89S51. Perangkat lunak dirancang berdasarkan analisis dan penurunan model matematis yang kemudian diimplementasikan dalam bahasa C. Simulasi dilakukan untuk memverifikasi bahwa rancangan pengendali memenuhi spesifikasi yang telah ditentukan untuk menstabilk...

  15. Reliability, Availability and Serviceability of Networks-on-Chip

    CERN Document Server

    Cota, Érika; Soares Lubaszewski, Marcelo

    2012-01-01

    This book presents an overview of the issues related to the test, diagnosis and fault-tolerance of Network on Chip-based systems. It is the first book dedicated to the quality aspects of NoC-based systems and will serve as an invaluable reference to the problems, challenges, solutions, and trade-offs related to designing and implementing state-of-the-art, on-chip communication architectures.

  16. Experiment list: SRX478588 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available nonTG sperm H3K4me2; Mus musculus; ChIP-Seq source_name=Sperm, non-transgenic, H3K4me2 ChIP || strain/backgr...ound=C57BL/6 || genotype/variation=non-transgenic offspring of C57BL/6; EF-1alpha (promoter)-KDM1A (transgen...e) sire (sire from 2nd generation of transgenic line 1) || tissue=sperm || chip a

  17. Experiment list: SRX760611 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available sue=Lung || cell type=Spleen red pulp macrophages with CD45.1 mark || chip antibody=anti-H3K4me2 || chip ant... and Dow, 3rd ed.) 10685327,94.7,12.3,21158 GSM1546026: MC h5 Chimera Spleen2 K4Me2; Mus musculus; ChIP-Seq ...source_name=Spleen red pulp macrophages with CD45.1 mark || strain=C57BL/6 || tis

  18. Experiment list: SRX760596 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ssue=Spleen || cell type=Spleen red pulp macrophages with CD45.1 mark || chip antibody=anti-H3K4me2 || chip ... source_name=Spleen red pulp macrophages with CD45.1 mark || strain=C57BL/6 || ti... and Dow, 3rd ed.) 14456016,93.2,21.5,28285 GSM1546011: MC f05 Chimera Spleen1 K4Me2; Mus musculus; ChIP-Seq

  19. Experiment list: SRX760597 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available sue=Spleen || cell type=Spleen red pulp macrophages with CD45.1 mark || chip antibody=anti-H3K27ac || chip a... and Dow, 3rd ed.) 12890847,97.8,11.3,4235 GSM1546012: MC f06 Chimera Spleen1 K27Ac; Mus musculus; ChIP-Seq ...source_name=Spleen red pulp macrophages with CD45.1 mark || strain=C57BL/6 || tis

  20. Experiment list: SRX760612 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available and Dow, 3rd ed.) 10245893,97.8,12.0,2412 GSM1546027: MC h6 Chimera Spleen2 K27Ac; Mus musculus; ChIP-Seq source_name=Spleen red pul...ue=Lung || cell type=Spleen red pulp macrophages with CD45.1 mark || chip antibody=anti-H3K27ac || chip anti

  1. A Novel Chip-based Spectrophotometer for Online Detection

    Institute of Scientific and Technical Information of China (English)

    Haoyuan Cai; Min-Hsien Wu; Zheng Cui

    2006-01-01

    A chip-based spectrophotometer integrated with optical fiber is successfully demonstrated. Grade concentration of lactate solution flowed through the chip to perform an online detection. The response time (100s) and Limit of Detection (LOD,50mg/L) of the device were measured. This device shows comparable performance with traditional commercial instrument,while greatly decreases the sample requirement per detection and reduces the size of total system, introducing a novel method for real-time detection.

  2. Experiment list: SRX736201 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SRX736201 hg19 TFs and others BRD4 Neural 90-8TL NA 21809477,90.2,33.6,30233 GSM1527926: DMSO... BRD4 ChIPseq; Homo sapiens; ChIP-Seq source_name=MPNST cells 90-8TL_DMSO || cell line=MPNST cell ...line 90-8TL || treated with=DMSO for 24hrs || chip antibody=BRD4 || chip antibody vendor=Bethyl http://dbarc

  3. Experiment list: SRX203388 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available cular Immunology, 2d ed, p20) 47665471,89.3,52.3,11244 GSM1033753: MM.1S Brd4 DMSO JL ChipSeq; Homo sapiens;... ChIP-Seq source_name=Chromatin IP against Brd4 in MM.1S (DMSO) || diagnosis=Multiple myeloma || chip antibo...reatment duration=24 hr || treatment drug=DMSO http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/eachData/bw/S

  4. Single-chip microprocessor that communicates directly using light.

    Science.gov (United States)

    Sun, Chen; Wade, Mark T; Lee, Yunsup; Orcutt, Jason S; Alloatti, Luca; Georgas, Michael S; Waterman, Andrew S; Shainline, Jeffrey M; Avizienis, Rimas R; Lin, Sen; Moss, Benjamin R; Kumar, Rajesh; Pavanello, Fabio; Atabaki, Amir H; Cook, Henry M; Ou, Albert J; Leu, Jonathan C; Chen, Yu-Hsin; Asanović, Krste; Ram, Rajeev J; Popović, Miloš A; Stojanović, Vladimir M

    2015-12-24

    Data transport across short electrical wires is limited by both bandwidth and power density, which creates a performance bottleneck for semiconductor microchips in modern computer systems--from mobile phones to large-scale data centres. These limitations can be overcome by using optical communications based on chip-scale electronic-photonic systems enabled by silicon-based nanophotonic devices. However, combining electronics and photonics on the same chip has proved challenging, owing to microchip manufacturing conflicts between electronics and photonics. Consequently, current electronic-photonic chips are limited to niche manufacturing processes and include only a few optical devices alongside simple circuits. Here we report an electronic-photonic system on a single chip integrating over 70 million transistors and 850 photonic components that work together to provide logic, memory, and interconnect functions. This system is a realization of a microprocessor that uses on-chip photonic devices to directly communicate with other chips using light. To integrate electronics and photonics at the scale of a microprocessor chip, we adopt a 'zero-change' approach to the integration of photonics. Instead of developing a custom process to enable the fabrication of photonics, which would complicate or eliminate the possibility of integration with state-of-the-art transistors at large scale and at high yield, we design optical devices using a standard microelectronics foundry process that is used for modern microprocessors. This demonstration could represent the beginning of an era of chip-scale electronic-photonic systems with the potential to transform computing system architectures, enabling more powerful computers, from network infrastructure to data centres and supercomputers.

  5. Power Cycle Testing of Press-Pack IGBT Chips

    OpenAIRE

    Frank, Øyvind Bjerke

    2014-01-01

    In this thesis the power cycling capability of individual press-pack IGBT chips is investigated. Press-pack is a packaging technology used for power semiconductors. For press-packs, both thermal and electrical contact to the semiconductor chip is obtained by the application of force on the package. Press-pack IGBTs is claimed by the manufacturers to be especially suitable for high-power applications with large variations in power output. Power cycle testing is an accelerated lifetime stress t...

  6. Experiment list: SRX688848 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available d prostate cancer cell line || treatment=vehicle || chip antibody=rabbit anti-ASH... prostate cancer cells, vehicle, ASH2 ChIP || cell line=VCaP || cell type=vertebral metastatic lesion-derive...agnosis=Carcinoma 25750434,89.3,6.2,7152 GSM1489926: vcap ash2l veh; Homo sapiens; ChIP-Seq source_name=VCaP

  7. Readout chip for the CMS pixel detector upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Rossini, Marco, E-mail: marco.rossini@phys.ethz.ch

    2014-11-21

    For the CMS experiment a new pixel detector is planned for installation during the extended shutdown in winter 2016/2017. Among the changes of the detector modified front end electronics will be used for higher efficiency at peak luminosity of the LHC and faster readout. The first prototype versions of the new readout chip have been designed and produced. The results of qualification and calibration for the new chip are presented in this paper.

  8. Test probe for surface mounted leadless chip carrier

    Science.gov (United States)

    Meyer, Kerry L.; Topolewski, John

    1989-05-23

    A test probe for a surface mounted leadless chip carrier is disclosed. The probed includes specially designed connector pins which allow size reductions in the probe. A thermoplastic housing provides spring action to ensure good mechanical and electrical contact between the pins and the contact strips of a leadless chip carrier. Other features include flexible wires molded into the housing and two different types of pins alternately placed in the housing. These features allow fabrication of a smaller and simpler test probe.

  9. Reconstitution of CHIP E3 Ubiquitin Ligase Activity

    OpenAIRE

    Ren, Hong Yu; Patterson, Cam; Cyr, Douglas M.; Rosser, Meredith F. N.

    2011-01-01

    CHIP, the carboxyl-terminus of Hsp70 interacting protein, is both an E3 ubiquitin ligase and an Hsp70 co-chaperone and is implicated in the degradation of cytosolic quality control and numerous disease substrates. CHIP has been shown to monitor the folding status of the CFTR protein, and we have successfully reconstituted this activity using a recombinant CFTR fragment consisting of the cytosolic NBD1 and R domains. We have found that efficient ubiquitination of substrates requires chaperone ...

  10. Analysis and Implementation of Traffic Buffering in EOS Chip Design

    Institute of Scientific and Technical Information of China (English)

    FENG Bo; LIU Hao; YIN Yan-fen

    2005-01-01

    The traffic buffering problems in the ethernet over synchronous digital hierarchy(EOS) are introduced and analyzed. Different solutionsare also presented in detail. Synchronous DRAM(SDRAM) is used as off-chip buffer to store-and-retransmission ethernet frames. A new and easy control design is introduced here. The buffer area size on chip is greatly reduced and the power dissipation is lowed at the same time.

  11. Experiment list: SRX398299 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available cinoma || chip antibody=None || antibody catalog number=None WCE || cell line=HT29 || cell type=Colon Carcin...on|Tissue Diagnosis=Adenocarcinoma 18380673,54.8,14.3,4635 GSM1296642: HT29 WCE ChipSeq; Homo sapiens; ChIP-Seq source_name=Colon Car...oma http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/each

  12. MAROC, a generic photomultiplier readout chip

    Energy Technology Data Exchange (ETDEWEB)

    Blin, S; Barrillon, P; La Taille, C de, E-mail: blin@lal.in2p3.f [CNRS/IN2p3/LAL-OMEGA, Universite Paris Sud, Bat.200, 91898 Orsay (France)

    2010-12-15

    The MAROC ASICs family is dedicated to the readout of 64-channel Multi Anode PMT and similar detectors. Its main roles are to correct the gain spread of MAPMT channels thanks to an individual variable gain preamplifier and to discriminate the input signals (from 50fC i.e 1/3 photo-electron) in order to produce 64 trigger outputs. A multiplexed analog charge output is also available with a dynamic range around 10 pe ( {approx} 1.6 pC) and a 12 bit Wilkinson ADC is embedded. Three versions of this chip have been submitted. MAROC 2 is the production version for the ATLAS luminometer and MAROC3 is a version with lower dissipation and significant improvements concerning the charge (30 pe: {approx} 5 pC) and trigger (discrimination from 10fC). This third version showed very good characteristics that are presented here.

  13. MAROC, a generic photomultiplier readout chip

    Science.gov (United States)

    Blin, S.; Barrillon, P.; de La Taille, C.

    2010-12-01

    The MAROC ASICs family is dedicated to the readout of 64-channel Multi Anode PMT and similar detectors. Its main roles are to correct the gain spread of MAPMT channels thanks to an individual variable gain preamplifier and to discriminate the input signals (from 50fC i.e 1/3 photo-electron) in order to produce 64 trigger outputs. A multiplexed analog charge output is also available with a dynamic range around 10 pe ( ~ 1.6 pC) and a 12 bit Wilkinson ADC is embedded. Three versions of this chip have been submitted. MAROC 2 is the production version for the ATLAS luminometer and MAROC3 is a version with lower dissipation and significant improvements concerning the charge (30 pe: ~ 5 pC) and trigger (discrimination from 10fC). This third version showed very good characteristics that are presented here.

  14. The principal and application of gene chips

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@Today we are living in an information era. Everyone can see what a tremendously change has been brought by the using of the computers. The advent of the computer chip let us embed our smarts in everything from satellite to greeting cards to internet.   People said that the human genome project is the second "Apollo". Human Genome Project, the international effort that is expected to unravel the structures of all 30 000 to 35 000 or so human genes by 2003. But deconstructing the genome is only the first step-like learning to pick out words in a foreign language before grappling with their meanings. Realizing the gene revolution's potential will require understanding how genes collaborate to cement memories in our brains, say, or how they malfunction to change a healthy adult into one dying of cancer. That's the goal of the second phase of the revolution, functional genomics.

  15. Droplet Microfluidics for Chip-Based Diagnostics

    Directory of Open Access Journals (Sweden)

    Karan V. I. S. Kaler

    2014-12-01

    Full Text Available Droplet microfluidics (DMF is a fluidic handling technology that enables precision control over dispensing and subsequent manipulation of droplets in the volume range of microliters to picoliters, on a micro-fabricated device. There are several different droplet actuation methods, all of which can generate external stimuli, to either actively or passively control the shape and positioning of fluidic droplets over patterned substrates. In this review article, we focus on the operation and utility of electro-actuation-based DMF devices, which utilize one or more micro-/nano-patterned substrates to facilitate electric field-based handling of chemical and/or biological samples. The underlying theory of DMF actuations, device fabrication methods and integration of optical and opto-electronic detectors is discussed in this review. Example applications of such electro-actuation-based DMF devices have also been included, illustrating the various actuation methods and their utility in conducting chip-based laboratory and clinical diagnostic assays.

  16. Octave Spanning Frequency Comb on a Chip

    CERN Document Server

    Del'Haye, P; Gavartin, E; Holzwarth, R; Kippenberg, T J

    2009-01-01

    Optical frequency combs have revolutionized the field of frequency metrology within the last decade and have become enabling tools for atomic clocks, gas sensing and astrophysical spectrometer calibration. The rapidly increasing number of applications has heightened interest in more compact comb generators. Optical microresonator based comb generators bear promise in this regard. Critical to their future use as 'frequency markers', is however the absolute frequency stabilization of the optical comb spectrum. A powerful technique for this stabilization is self-referencing, which requires a spectrum that spans a full octave, i.e. a factor of two in frequency. In the case of mode locked lasers, overcoming the limited bandwidth has become possible only with the advent of photonic crystal fibres for supercontinuum generation. Here, we report for the first time the generation of an octave-spanning frequency comb directly from a toroidal microresonator on a silicon chip. The comb spectrum covers the wavelength range...

  17. CERN_DxCTA counting mode chip

    CERN Document Server

    Moraes, D; Nygård, E

    2008-01-01

    This ASIC is a counting mode front-end electronic optimized for the readout of CdZnTe/CdTe and silicon sensors, for possible use in applications where the flux of ionizing radiation is high. The chip is implemented in 0.25 μm CMOS technology. The circuit comprises 128 channels equipped with a transimpedance amplifier followed by a gain shaper stage with 21 ns peaking time, two discriminators and two 18-bit counters. The channel architecture is optimized for the detector characteristics in order to achieve the best energy resolution at counting rates of up to 5 M counts/second. The amplifier shows a linear sensitivity of 118 mV/fC and an equivalent noise charge of about 711 e−, for a detector capacitance of 5 pF. Complete evaluation of the circuit is presented using electronic pulses and pixel detectors.

  18. Wideband pulse amplifiers for the NECTAr chip

    Energy Technology Data Exchange (ETDEWEB)

    Sanuy, A., E-mail: asanuy@ecm.ub.es [Dept. AM i Dept. ECM, Institut de Ciencies del Cosmos (ICC), Universitat de Barcelona. Marti i Franques 1, E08028, Barcelona (Spain); Delagnes, E. [IRFU/DSM/CEA, CE-Saclay, Bat. 141 SEN Saclay, F-91191, Gif-sur-Yvette (France); Gascon, D. [Dept. AM i Dept. ECM, Institut de Ciencies del Cosmos (ICC), Universitat de Barcelona. Marti i Franques 1, E08028, Barcelona (Spain); Sieiro, X. [Departament d' Electronica, Universitat de Barcelona. Marti i Franques 1, E08028, Barcelona (Spain); Bolmont, J.; Corona, P. [LPNHE, Universite Paris VI and Universite Paris VII and IN2P3/CNRS, Barre 12-22, 1er etage, 4 place Jussieu, 75252 Paris (France); Feinstein, F. [LUPM, Universite Montpellier II and IN2P3/CNRS, CC072, bat. 13, place Eugene Bataillon, 34095 Montpellier (France); Glicenstein, J-F. [IRFU/DSM/CEA, CE-Saclay, Bat. 141 SEN Saclay, F-91191, Gif-sur-Yvette (France); Naumann, C.L.; Nayman, P. [LPNHE, Universite Paris VI and Universite Paris VII and IN2P3/CNRS, Barre 12-22, 1er etage, 4 place Jussieu, 75252 Paris (France); Ribo, M. [Dept. AM i Dept. ECM, Institut de Ciencies del Cosmos (ICC), Universitat de Barcelona. Marti i Franques 1, E08028, Barcelona (Spain); and others

    2012-12-11

    The NECTAr collaboration's FE option for the camera of the CTA is a 16 bits and 1-3 GS/s sampling chip based on analog memories including most of the readout functions. This works describes the input amplifiers of the NECTAr ASIC. A fully differential wideband amplifier, with voltage gain up to 20 V/V and a BW of 400 MHz. As it is impossible to design a fully differential OpAmp with an 8 GHz GBW product in a 0.35 CMOS technology, an alternative implementation based on HF linearized transconductors is explored. The output buffer is a class AB miller operational amplifier, with special non-linear current boost.

  19. Synchronization of Integrated Systems on a Chip

    Directory of Open Access Journals (Sweden)

    González-Díaz O.

    2012-04-01

    Full Text Available In the present paper, the non-conventional interconnected and coupled ring oscillators approach working as clock distribution networks to synchronize electronic systems on a chip (SoC is proposed. Typical CMOS (Complementary Metal-Oxide Semiconductor N-well 0.35 µm Austria Micro Systems process parameters were used for conventional and non-conventional clock distribution nets design and simulation. Experimental results from local and global clock distribution networks fabricated using a CMOS 0.35 µm process show that the use of interconnected rings arrays, as globally asynchronous locally synchronous (GALS clock distribution networks, represent an appropriate approach due to good performance regarding scalability, low clock-skew, high-speed, faults tolerant and robust under process variations, regularity, and modularity.

  20. Invisibility Cloak Printed on a Photonic Chip

    CERN Document Server

    Feng, Zhen; Zhao, Yu-Xi; Gao, Jun; Qiao, Lu-Feng; Yang, Ai-Lin; Lin, Xiao-Feng; Jin, Xian-Min

    2016-01-01

    Invisibility cloak capable of hiding an object can be achieved by properly manipulating electromagnetic field. Such a remarkable ability has been shown in transformation and ray optics. Alternatively, it may be realistic to create a spatial cloak by means of confining electromagnetic field in three-dimensional arrayed waveguides and introducing appropriate collective curvature surrounding an object. We realize the artificial structure in borosilicate by femtosecond laser direct writing, where we prototype up to 5000 waveguides to conceal millimeter-scale volume. We characterize the performance of the cloak by normalized cross correlation, tomography analysis and continuous three-dimensional viewing angle scan. Our results show invisibility cloak can be achieved in waveguide optics. Furthermore, directly printed invisibility cloak on a photonic chip may enable controllable study and novel applications in classical and quantum integrated photonics, such as invisualising a coupling or swapping operation with on-...

  1. A contact-lens-shaped IC chip technology

    International Nuclear Information System (INIS)

    We report on novel contact-lens-shaped silicon integrated circuit chip technology for applications such as forming a conforming retinal prosthesis. This is achieved by means of patterning thin films of high residual stress on top of a shaped thin silicon substrate. Several strategies are employed to achieve curvatures of various amounts. Firstly, high residual stress on a thin film makes a thin chip deform into a designed three-dimensional shape. Also, a series of patterned stress films and ‘petal-shaped’ chips were fabricated and analyzed. Large curvatures can also be formed and maintained by the packaging process of bonding the chips to constraining elements such as thin-film polymer ring structures. As a demonstration, a complementary metal oxide semiconductor transistor (CMOS) image-sensing retina chip is made into a contact-lens shape conforming to a human eyeball 12.5 mm in radius. This non-planar and flexible chip technology provides a desirable device surface interface to soft tissues or non-planar bio surfaces and opens up many other possibilities for biomedical applications. (paper)

  2. Chipping operations and efficiency in different operational environments

    Energy Technology Data Exchange (ETDEWEB)

    Roeser, D.; Mola-Yudego, B.; Prinz, R.; Emer, B.; Sikanen, L., e-mail: dominik.roser@metla.fi

    2012-11-01

    This research analyses the productivity of energy wood chipping operations at several sites in Austria and Finland. The aim of the work is to examine the differences in productivity and the effects of the operational environment for the chipping of bioenergy at the roadside. Furthermore, the study quantifies the effects of different variables such as forest energy assortments, tree species, sieve size and machines on the overall productivity of chipping. The results revealed that there are significant differences in the chipping productivity in Austria and Finland which are largely based on the use of different sieve sizes. Furthermore, the different operational environments in both countries, as well as the characteristics of the raw material also seem to have an effect on productivity. In order to improve the chipping productivity, particularly in Central European conditions, all relevant stakeholders need to work jointly to find solutions that will allow a greater variation of chip size. Furthermore, in the future more consideration has to be given to the close interlinkage between the chipper, crane and grapple. As a result, investments costs can be optimized and operational costs and stress on the machines reduced. (orig.)

  3. Dynamic On-Chip micro Temperature and Flow Sensor for miniaturized lab-on-a-chip instruments Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The purpose of this project is to design, fabricate, and characterize a Dynamic On-Chip Flow and Temperature Sensor (DOCFlaTS) to mature and enable miniaturized...

  4. An investigation of cutting mechanics in 2 dimensional ultrasonic vibration assisted milling toward chip thickness and chip formation

    Science.gov (United States)

    Rasidi, I. I.; Rafai, N. H.; Rahim, E. A.; Kamaruddin, S. A.; Ding, H.; Cheng, K.

    2015-12-01

    The purpose of this paper is to investigate the effects of 2 dimensional Ultrasonic Vibration Assisted Milling (UVAM) cutting mechanics, considering tool path trajectory and the effect on the chip thickness. The theoretical modelling of cutting mechanics is focused by considering the trajectory of the tool locus into the workpiece during the machining. The studies found the major advantages of VAM are come from the intermittent tool tip interaction phenomena between cutting tool and workpiece. The reduction of thinning chip thickness formations can be identifying advantages from vibration assisted milling in 2 dimensional. The finding will be discussing the comparison between conventional machining the potential of the advantages toward the chip thickness and chip formation in conclusion.

  5. FISH & CHIPS: Four Electrode Conductivity / Salinity Sensor on a Silicon Multi-sensor chip for Fisheries Research

    DEFF Research Database (Denmark)

    Hyldgård, Anders; Olafsdottir, Iris; Olesen, M.;

    2005-01-01

    The design and fabrication of a single chip silicon salinity, temperature, pressure and light multisensor is presented. The behavior 2- and 4-electrode conductivity microsensors are described and methods for precise determination of water conductivity are given......The design and fabrication of a single chip silicon salinity, temperature, pressure and light multisensor is presented. The behavior 2- and 4-electrode conductivity microsensors are described and methods for precise determination of water conductivity are given...

  6. Cost and profitability of biofuel chipping in Alnus incana stands in Lithuania

    Energy Technology Data Exchange (ETDEWEB)

    Mizaras, Stasys; Sadauskiene, Liana; Mizaraite, Diana (Department of Forest Resources, Economics and Policy, Lithuanian Research Centre for Agriculture and Forestry, Inst. of Forestry, Girionys, (Lithuania)), e-mail: l.sadauskiene@mi.lt

    2011-07-01

    The demand for forest fuels is increasing in Lithuania. One biofuel source could be grey alder stands, which are currently underused. This study examines the economic feasibility of producing chips from grey alder stands. The research was performed on three grey alder stands. Three chip production technologies were analysed: chips from logging residues, stemwood chips and whole-tree chips. Work time expenditures and costs were assessed for each mode of chip production. When raw material for chips are sold at the roadside, their production from logging residues is usually not profitable. Profitability of whole-tree raw material for chips depends on forwarding distance. Production of raw material for chips from stemwood is profitable. When chips are sold at the heating plant, production is profitable if the chips are made from stemwood and whole trees. Production of chips from logging residues can be profitable if forwarding distances are short. If it is desired to promote the use of grey alder stands for fuel, the problem of the competing profitability of this raw material for chip production should be solved by instituting subsidies or increasing its price

  7. Characterizing Rat PNS Electrophysiological Response to Electrical Stimulation Using in vitro Chip-Based Human Investigational Platform (iCHIP)

    Energy Technology Data Exchange (ETDEWEB)

    Khani, Joshua [Georgetown Univ., Washington, DC (United States); Prescod, Lindsay [Georgetown Univ., Washington, DC (United States); Enright, Heather [Georgetown Univ., Washington, DC (United States); Felix, Sarah [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Osburn, Joanne [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Wheeler, Elizabeth [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kulp, Kris [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2015-08-18

    Ex vivo systems and organ-on-a-chip technology offer an unprecedented approach to modeling the inner workings of the human body. The ultimate goal of LLNL’s in vitro Chip-based Human Investigational Platform (iCHIP) is to integrate multiple organ tissue cultures using microfluidic channels, multi-electrode arrays (MEA), and other biosensors in order to effectively simulate and study the responses and interactions of the major organs to chemical and physical stimulation. In this study, we focused on the peripheral nervous system (PNS) component of the iCHIP system. Specifically we sought to expound on prior research investigating the electrophysiological response of rat dorsal root ganglion cells (rDRGs) to chemical exposures, such as capsaicin. Our aim was to establish a protocol for electrical stimulation using the iCHIP device that would reliably elicit a characteristic response in rDRGs. By varying the parameters for both the stimulation properties – amplitude, phase width, phase shape, and stimulation/ return configuration – and the culture conditions – day in vitro and neural cell types - we were able to make several key observations and uncover a potential convention with a minimal number of devices tested. Future work will seek to establish a standard protocol for human DRGs in the iCHIP which will afford a portable, rapid method for determining the effects of toxins and novel therapeutics on the PNS.

  8. Fully Automated On-Chip Imaging Flow Cytometry System with Disposable Contamination-Free Plastic Re-Cultivation Chip

    Directory of Open Access Journals (Sweden)

    Tomoyuki Kaneko

    2011-06-01

    Full Text Available We have developed a novel imaging cytometry system using a poly(methyl methacrylate (PMMA based microfluidic chip. The system was contamination-free, because sample suspensions contacted only with a flammable PMMA chip and no other component of the system. The transparency and low-fluorescence of PMMA was suitable for microscopic imaging of cells flowing through microchannels on the chip. Sample particles flowing through microchannels on the chip were discriminated by an image-recognition unit with a high-speed camera in real time at the rate of 200 event/s, e.g., microparticles 2.5 μm and 3.0 μm in diameter were differentiated with an error rate of less than 2%. Desired cells were separated automatically from other cells by electrophoretic or dielectrophoretic force one by one with a separation efficiency of 90%. Cells in suspension with fluorescent dye were separated using the same kind of microfluidic chip. Sample of 5 μL with 1 × 106 particle/mL was processed within 40 min. Separated cells could be cultured on the microfluidic chip without contamination. The whole operation of sample handling was automated using 3D micropipetting system. These results showed that the novel imaging flow cytometry system is practically applicable for biological research and clinical diagnostics.

  9. Avaliação da aceitação de "chips" de mandioca Acceptance evaluation of cassava chips

    Directory of Open Access Journals (Sweden)

    Regina Kitagawa Grizotto

    2003-12-01

    Full Text Available Pré-tratamentos como o cozimento, a fermentação natural e a secagem parcial foram aplicados em raízes de mandioca, visando a obtenção de "chips" comestíveis. A avaliação sensorial foi feita com base na aceitação e aparência dos "chips" das variedades IAC Mantiqueira e IAC 576.70. Trinta consumidores potenciais do produto foram selecionados em função da disponibilidade e interesse em participar dos testes. Foi utilizada escala hedônica de 7 pontos, onde os provadores avaliaram as amostras delineadas em blocos casualizados. Os resultados obtidos mostraram que os "chips" controle e pré-cozidos foram aceitos sensorialmente, apresentado médias de 5,1 (gostei ligeiramente para IAC Mantiqueira e 6,0 (gostei moderadamente para IAC 576.70. Os "chips" pré-fermentados de ambas variedades foram rejeitados. Os termos de agrado mais comentados pelos provadores foram "sabor de mandioca", "crocância" e "textura". Os termos de desagrado mais citados incluem "textura dura", "falta sabor de mandioca" e "gosto de óleo". Os provadores consideraram adequada a aparência dos "chips" de ambas variedades, sendo ligeiramente preferida a aparência dos "chips" da IAC 576.70, com exceção dos "chips" cozidos por 8 minutos e os fermentados, rejeitados pelos consumidores. A cor amarela da polpa pode ter influenciado a aceitação da variedade IAC 576.70. A composição centesimal e o teor de fibras na mandioca in natura e, o teor de lipídeos em "chips" de mandioca, também foram apresentados.Pre-treatments such as cooking, natural fermentation and partial drying were applied to cassava roots, aimed at obtaining edible cassava chips. The sensory evaluation was based on the acceptance and appearance of the chips, using the varieties IAC Mantiqueira and IAC 576.70. Thirty potential consumers of the product were selected based on their availability and interest. A 7-point hedonic scale was used, all the judges evaluating all the samples using a randomised

  10. INVESTIGATION OF PHYSICOCHEMICAL AND MECHANICAL CHARACTERISTICS OF STEEL AND CAST IRON CHIPS

    Directory of Open Access Journals (Sweden)

    O. M. Dyakonov

    2009-01-01

    Full Text Available The chemical and phase composition of steel and cast iron chips is studied, quantitative content of phases, including ferric oxides and other chemical elements chips, is determined.

  11. Development of Microreactor Array Chip-Based Measurement System for Massively Parallel Analysis of Enzymatic Activity

    Science.gov (United States)

    Hosoi, Yosuke; Akagi, Takanori; Ichiki, Takanori

    Microarray chip technology such as DNA chips, peptide chips and protein chips is one of the promising approaches for achieving high-throughput screening (HTS) of biomolecule function since it has great advantages in feasibility of automated information processing due to one-to-one indexing between array position and molecular function as well as massively parallel sample analysis as a benefit of down-sizing and large-scale integration. Mostly, however, the function that can be evaluated by such microarray chips is limited to affinity of target molecules. In this paper, we propose a new HTS system of enzymatic activity based on microreactor array chip technology. A prototype of the automated and massively parallel measurement system for fluorometric assay of enzymatic reactions was developed by the combination of microreactor array chips and a highly-sensitive fluorescence microscope. Design strategy of microreactor array chips and an optical measurement platform for the high-throughput enzyme assay are discussed.

  12. Recycling of AlMgSi1 aluminium chips by cold compression

    Directory of Open Access Journals (Sweden)

    T. Pepelnjak

    2012-10-01

    Full Text Available Current work elaborates possibilities for direct conversion of AlMgSi1 aluminium chips into solid billets by solid state recycling. Milling chips from an aluminium alloy were cold compressed in a closed cylindrical die by means of a 2,5 MN hydraulic press. Due to low initial relative density of the chips, several pre-compressions were needed. In order to establish the infl uence of chip geometry on the final density of billets different types of chips were cut by using various milling regimes. The infl uence of a compression regime due to various chip types were followed by load–stroke diagrams. Up to 97 % of density measured at extruded aluminium was attained for one type of chips. Results show that the shapes of the chips and their size (especially thickness have a considerable infl uence on the final integrity of billets.

  13. Brain Chips Help Paralyzed Man Regain Sense of Touch Using Robotic Arm

    Science.gov (United States)

    ... https://medlineplus.gov/news/fullstory_161466.html Brain Chips Help Paralyzed Man Regain Sense of Touch Using ... to overcome. A set of four brain implants -- chips half the size of a dress shirt button -- ...

  14. 77 FR 14424 - Certain Semiconductor Chips and Products Containing Same; Request for Statements On the Public...

    Science.gov (United States)

    2012-03-09

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Certain Semiconductor Chips and Products Containing Same; Request for Statements On the Public... supplier respondents' accused semiconductor chips; and cease and desist orders against five...

  15. 78 FR 24234 - Certain Semiconductor Chips With DRAM Circuitry, and Modules and Products Containing Same; Notice...

    Science.gov (United States)

    2013-04-24

    ... From the Federal Register Online via the Government Publishing Office ] INTERNATIONAL TRADE COMMISSION Certain Semiconductor Chips With DRAM Circuitry, and Modules and Products Containing Same; Notice..., which is a limited exclusion order barring the entry of unlicensed DRAM semiconductor chips...

  16. Network-on-chip the next generation of system-on-chip integration

    CERN Document Server

    Kundu, Santanu

    2014-01-01

    ""What makes this book special as compared to the current literature in the field is that it provides a complete picture of NoC architectures. In fact, current books in the context of NoCs are usually specific and presuppose a basic knowledge of NoC architectures. Conversely, this book provides a complete guide for both unskilled readers and researchers working in the area, to acquire not only the basic concepts but also the advanced techniques for improving power, cost and performance metrics of the on-chip communication system.""-Maurizio Palesi, Kore University, Italy.

  17. Logistics of in-wood chipping and trucking of chips; Palstahaketuksen logistinen ketju

    Energy Technology Data Exchange (ETDEWEB)

    Nuuja, J. [Joensuu Univ. (Finland). Faculty of Forestry; Asikainen, A. [Metsaeosaamiskeskus, Joensuu (Finland). Joensuu Science Park

    1996-12-31

    In this study a in wood chipper and truck transport of chips were modelled and studied by discrete-event simulation. The input data, which included stand characteristics and information about transport distances was compiled by GRASS-program. This data based on the inventory done by Forestry Center TAPIO. With the model various transport alternatives were compared and the effect of work condition factors were studied. It was find out, that a long distance transport with interchangeable container truck gives better productivity than a truck with a trailer. This results from shorter loading time for the interchangeable container truck

  18. Temporal and Spatial Isolation and Protection of Program Modules for an Embedded System-on-Chip

    OpenAIRE

    Vermeer, Håvard

    2011-01-01

    Nordic Semiconductor ASA wishes to improve its product value by enabling Bluetooth Low Energy functionality on their new Cortex-M0 based radio microcontrollers.The new device will be single-chip, thereby evolving their current dual-chip solution.% using a single chip, thereby evolving their current dual-chip solution. This report handles the challenge of protecting the radio subsystem from the user applications since they now must reside on the same microcontroller.The Bluetooth Low Energy pr...

  19. HTS and PCT Reliability of Chips and Flex Substrates Assembled Using a Thermosonic Flip-Chip Bonding Process

    Science.gov (United States)

    Chuang, Cheng-Li; Kang, Min-Yi

    2012-09-01

    This study assesses the high-temperature storage (HTS) test and the pressure-cooker test (PCT) reliability of an assembly of chips and flexible substrates. After the chips were bonded onto the flexible substrates, specimens were utilized to assess the HTS test and PCT reliability. After the PCT and HTS tests, the die-shear test was applied to examine changes in die-shear forces. The microstructure of the test specimens was analyzed to evaluate reliability and to identify possible failure mechanisms. When the duration of the HTS test was increased, the percentage of gold bumps that peeled off from the surface of the copper pads on the chip side increased, and a crack was present at the bonding interface between the gold bumps and chip bond pads. This crack was due to thermal stress generated during the HTS test, and degraded the die-shear force of the assembly of chips and flexible substrates. After the PCT, the crack was present at the interface between deposited layers of copper electrodes after the specimens were subjected to the PCT for various durations. Moisture penetrated into the deposited layers of the copper electrodes, deposited layers lost their adhesion, and the crack progressed from the corner into the central bond area as the test duration increased. To improve the PCT reliability of assemblies of chips and flexible substrates using the thermosonic flip-chip bonding process, one must prevent moisture from penetrating into deposited layers of copper electrodes and prevent crack formation at the interface between nickel and copper layers. Underfill would be an effective approach to prevent moisture from penetrating into deposited layers during the PCT, thereby improving the reliability of the samples during the PCT.

  20. A system-level multiprocessor system-on-chip modeling framework

    DEFF Research Database (Denmark)

    Virk, Kashif Munir; Madsen, Jan

    2004-01-01

    We present a system-level modeling framework to model system-on-chips (SoC) consisting of heterogeneous multiprocessors and network-on-chip communication structures in order to enable the developers of today's SoC designs to take advantage of the flexibility and scalability of network-on-chip and...

  1. 21 CFR 102.41 - Potato chips made from dried potatoes.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Potato chips made from dried potatoes. 102.41... Specific Nonstandardized Foods § 102.41 Potato chips made from dried potatoes. (a) The common or usual name of the food product that resembles and is of the same composition as potato chips, except that it...

  2. Chlorhexidine Chip in the Treatment of Chronic Periodontitis – A Clinical Study

    OpenAIRE

    Medaiah, Sangeetha; Srinivas, M; Melath, Anil; Girish, Suragimath; Polepalle, Tejaswin; Dasari, Ankineedu Babu

    2014-01-01

    Aim: The aim of this study was to clinically evaluate the use of biodegradable chlorhexidine chip when used as an adjunct to scaling and root planing (SRP) in the treatment of moderate to severe periodontitis patients. The study also intended to compare the combined therapy (SRP and Chlorhexidine chip) with chlorhexidine chip alone in individuals with periodontitis.

  3. Roll-to-plate fabrication of microfluidic chips with thiol-ene resins

    DEFF Research Database (Denmark)

    Senkbeil, Silja; Yde, Leif; Lindvold, Lars R.;

    2015-01-01

    This paper demonstrates the fabrication and performance of a capillary electrophoresis (CE) chip with a UV-assisted roll-to-plate fabrication mechanism. Patterning and lamination of the chip can be performed with fabrication speeds of up to 19 m/min (ca. 20 chips/min), offering a rapid and simple...

  4. The behavior of Chip Firing Game and related model: A comprehensive survey

    Directory of Open Access Journals (Sweden)

    Le Manh Ha

    2015-11-01

    Full Text Available In this paper, we give a survey of known results concerning the presence of order structure and lattices in the context of discrete dynamical models derived from studies of Chip Firing Games. Index Terms—Chip Firing Game, Conflicting Chip Firing Game, Discrete dynamical system, order and lattice structure, Petri net, Rotor router.

  5. 42 CFR 431.974 - Basic elements of Medicaid and CHIP eligibility reviews.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Basic elements of Medicaid and CHIP eligibility... ADMINISTRATION Requirements for Estimating Improper Payments in Medicaid and CHIP § 431.974 Basic elements of Medicaid and CHIP eligibility reviews. (a) General requirements. (1) States selected in any given year...

  6. 42 CFR 457.216 - Treatment of uncashed or canceled (voided) CHIP checks.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Treatment of uncashed or canceled (voided) CHIP... canceled (voided) CHIP checks. (a) Purpose. This section provides rules to ensure that States refund the... section— Canceled (voided) check means an CHIP check issued by a State or fiscal agent that prior to...

  7. 78 FR 45208 - Children's Health Insurance Program (CHIP); Final Allotments to States, the District of Columbia...

    Science.gov (United States)

    2013-07-26

    ... September 16, 2009 Federal Register (74 FR 47517) which contained the FY 2009 CHIP allotments, the February 17, 2011 Federal Register (76 FR 9233) which contained the FY 2010 and FY 2011 CHIP allotments, and the July 24, 2012 Federal Register (77 FR 43290) which contained the FY 2012 CHIP allotments. ] 3....

  8. Identifying Professional Competencies of the Flip-Chip Packaging Engineer in Taiwan

    Science.gov (United States)

    Guu, Y. H.; Lin, Kuen-Yi; Lee, Lung-Sheng

    2014-01-01

    This study employed a literature review, expert interviews, and a questionnaire survey to construct a set of two-tier competencies for a flip-chip packaging engineer. The fuzzy Delphi questionnaire was sent to 12 flip-chip engineering experts to identify professional competencies that a flip-chip packaging engineer must have. Four competencies,…

  9. 75 FR 3904 - Appointments to the Medicaid and CHIP Payment and Access Commission (MACPAC)

    Science.gov (United States)

    2010-01-25

    ... OFFICE Appointments to the Medicaid and CHIP Payment and Access Commission (MACPAC) AGENCY: Government... Reauthorization Act of 2009 established MACPAC to review Medicaid and CHIP access and payment policies and to advise Congress on issues affecting Medicaid and CHIP. The Act directs the Comptroller General to...

  10. A polymer chip-integrable piezoelectric micropump with low backpressure dependence

    DEFF Research Database (Denmark)

    Conde, A. J.; Bianchetti, A.; Veiras, F. E.;

    2015-01-01

    We describe a piezoelectric micropump constructed in polymers with conventional machining methods. The micropump is self-contained and can be built as an independent device or as an on-chip module within laminated microfluidic chips. We demonstrate on-chip integrability by the fabrication and tes...

  11. 76 FR 72214 - Certain Semiconductor Chips with DRAM Circuitry, and Modules and Products Containing Same Receipt...

    Science.gov (United States)

    2011-11-22

    ... COMMISSION Certain Semiconductor Chips with DRAM Circuitry, and Modules and Products Containing Same Receipt... Commission has received a complaint entitled In Re Certain Semiconductor Chips with DRAM Circuitry, and... importation of certain semiconductor chips with dram circuitry, and modules and products containing same....

  12. 76 FR 384 - Certain Semiconductor Chips and Products Containing Same; Notice of Investigation

    Science.gov (United States)

    2011-01-04

    ... COMMISSION Certain Semiconductor Chips and Products Containing Same; Notice of Investigation AGENCY: U.S... importation of certain semiconductor chips and products containing same by reason of infringement of certain... after importation of certain semiconductor chips and products containing same that infringe one or...

  13. Silicon integrated nanophotonics for on-chip interconnects

    Science.gov (United States)

    Vlasov, Yurii

    2008-03-01

    Current trend in microelectronics industry is to increase the parallelism in computation by multi-threading, by building large scale multi-chip systems and, more recently, by increasing the number of cores on a single chip. With such increase of parallelization the interconnect bandwidth between the racks, chips or different cores is becoming a limiting factor for the design of high performance computer systems. The on-chip ultrahigh-bandwidth silicon-based photonic network might provide an attractive solution to this bandwidth bottleneck. We will review recent results on silicon nanophotonic circuits based on photonic wires and photonic crystals. Strong light confinement at the diffraction limit enables dramatic scaling of the device area and allows unprecedented control over optical signals. Silicon nanophotonic devices have immense capacity for low-loss, high-bandwidth data processing that might enable the design of ultra-compact on-chip optical networks. In particular we will show recent results on design and characterization of various ultra-compact (circuits as optical delay lines, electro-optic modulators, broadband optical switches, wavelength filters, etc.

  14. On-chip enucleation of an oocyte by untethered microrobots

    Science.gov (United States)

    Ichikawa, Akihiko; Sakuma, Shinya; Sugita, Masakuni; Shoda, Tatsuro; Tamakoshi, Takahiro; Akagi, Satoshi; Arai, Fumihito

    2014-09-01

    We propose a novel on-chip enucleation of an oocyte with zona pellucida by using a combination of untethered microrobots. To achieve enucleation within the closed space of a microfluidic chip, two microrobots, a microknife and a microgripper were integrated into the microfluidic chip. These microrobots were actuated by an external magnetic force produced by permanent magnets placed on the robotic stage. The tip of the microknife was designed by considering the biological geometric feature of an oocyte, i.e. the oocyte has a polar body in maturation stage II. Moreover, the microknife was fabricated by using grayscale lithography, which allows fabrication of three-dimensional microstructures. The microgripper has a gripping function that is independent of the driving mechanism. On-chip enucleation was demonstrated, and the enucleated oocytes are spherical, indicating that the cell membrane of the oocytes remained intact. To confirm successful enucleation using this method, we investigated the viability of oocytes after enucleation. The results show that the production rate, i.e. the ratio between the number of oocytes that reach the blastocyst stage and the number of bovine oocytes after nucleus transfer, is 100%. The technique will contribute to complex cell manipulation such as cell surgery in lab-on-a-chip devices.

  15. Nanoimprinted nanopillar array chip for procalcitonin detection (Conference Presentation)

    Science.gov (United States)

    Sun, Ling Ling; Zhou, Xiaodong

    2016-03-01

    Procalcitonin (PCT) is an early and highly specific biomarker in response to bacterial infection. The PCT-guided antibiotic therapy has demonstrated to be more efficient than standard therapy to reduce in antibiotic use without adverse outcome in mortality. The PCT detection in clinics is required to be highly sensitive with a sensitivity of 0.5 ng/ml. At present, the technologies for PCT detection are limited. This paper reported a highly sensitive nanoimprinted gold nanopillar array chip for PCT detection. To achieve high sensitivity for PCT detection, the gold nanopillar array sensing chip was designed by plasmonic simulation and fabricated by high fidelity nanoimprinting technology. The gold nanopillars of 140 nm were nanoimprinted on glass substrate. A robust sandwich bioassay of capture antibody /PCT / quantum dot (QD) conjugated detection antibody was established on the gold nanopillar array chip to detect PCT. The nanopillars serve as localized surface plasmon resonance (LSPR) generators to enhance the fluorescent emission from QD. A limit of detection (LOD) of 0.5 ng/ml was achieved for PCT detection. This is the first time that PCT is detected with such high sensitivity by LSPR enhanced QD emission. By considering the low-cost, high sensitivity of the bioassay, as well as the inexpensive mass fabrication of the high quality chips, this novel nanoimprinted gold nanopillar array chip is particularly useful for developing a point-of-care system for PCT detection.

  16. Using Ant Colony Optimization for Routing in VLSI Chips

    Science.gov (United States)

    Arora, Tamanna; Moses, Melanie

    2009-04-01

    Rapid advances in VLSI technology have increased the number of transistors that fit on a single chip to about two billion. A frequent problem in the design of such high performance and high density VLSI layouts is that of routing wires that connect such large numbers of components. Most wire-routing problems are computationally hard. The quality of any routing algorithm is judged by the extent to which it satisfies routing constraints and design objectives. Some of the broader design objectives include minimizing total routed wire length, and minimizing total capacitance induced in the chip, both of which serve to minimize power consumed by the chip. Ant Colony Optimization algorithms (ACO) provide a multi-agent framework for combinatorial optimization by combining memory, stochastic decision and strategies of collective and distributed learning by ant-like agents. This paper applies ACO to the NP-hard problem of finding optimal routes for interconnect routing on VLSI chips. The constraints on interconnect routing are used by ants as heuristics which guide their search process. We found that ACO algorithms were able to successfully incorporate multiple constraints and route interconnects on suite of benchmark chips. On an average, the algorithm routed with total wire length 5.5% less than other established routing algorithms.

  17. AC Zeeman potentials for atom chip-based ultracold atoms

    Science.gov (United States)

    Fancher, Charles; Pyle, Andrew; Ziltz, Austin; Aubin, Seth

    2015-05-01

    We present experimental and theoretical progress on using the AC Zeeman force produced by microwave magnetic near-fields from an atom chip to manipulate and eventually trap ultracold atoms. These AC Zeeman potentials are inherently spin-dependent and can be used to apply qualitatively different potentials to different spin states simultaneously. Furthermore, AC Zeeman traps are compatible with the large DC magnetic fields necessary for accessing Feshbach resonances. Applications include spin-dependent trapped atom interferometry and experiments in 1D many-body physics. Initial experiments and results are geared towards observing the bipolar detuning-dependent nature of the AC Zeeman force at 6.8 GHz with ultracold 87Rb atoms trapped in the vicinity of an atom chip. Experimental work is also underway towards working with potassium isotopes at frequencies of 1 GHz and below. Theoretical work is focused on atom chip designs for AC Zeeman traps produced by magnetic near-fields, while also incorporating the effect of the related electric near-fields. Electromagnetic simulations of atom chip circuits are used for mapping microwave propagation in on-chip transmission line structures, accounting for the skin effect, and guiding impedance matching.

  18. Adsorbate Electric Fields on a Cryogenic Atom Chip

    CERN Document Server

    Chan, K S; Hufnagel, C; Dumke, R

    2013-01-01

    We investigate the behaviour of electric fields originating from adsorbates deposited on a cryogenic atom chip as it is cooled from room temperature to cryogenic temperature. Using Rydberg electromagnetically induced transparency we measure the field strength versus distance from a 1 mm square of YBCO patterned onto a YSZ chip substrate. We find a localized and stable dipole field at room temperature and attribute it to a saturated layer of chemically adsorbed rubidium atoms on the YBCO. As the chip is cooled towards 83 K we observe a change in sign of the electric field as well as a transition from a localized to a delocalized dipole density. We relate these changes to the onset of physisorption on the chip surface when the van der Waals attraction overcomes the thermal desorption mechanisms. Our findings suggest that, through careful selection of substrate materials, it may be possible to reduce the electric fields caused by atomic adsorption on chips, opening up experiments to controlled Rydberg-surface co...

  19. CATCHprofiles: clustering and alignment tool for ChIP profiles.

    Directory of Open Access Journals (Sweden)

    Fiona G G Nielsen

    Full Text Available Chromatin Immuno Precipitation (ChIP profiling detects in vivo protein-DNA binding, and has revealed a large combinatorial complexity in the binding of chromatin associated proteins and their post-translational modifications. To fully explore the spatial and combinatorial patterns in ChIP-profiling data and detect potentially meaningful patterns, the areas of enrichment must be aligned and clustered, which is an algorithmically and computationally challenging task. We have developed CATCHprofiles, a novel tool for exhaustive pattern detection in ChIP profiling data. CATCHprofiles is built upon a computationally efficient implementation for the exhaustive alignment and hierarchical clustering of ChIP profiling data. The tool features a graphical interface for examination and browsing of the clustering results. CATCHprofiles requires no prior knowledge about functional sites, detects known binding patterns "ab initio", and enables the detection of new patterns from ChIP data at a high resolution, exemplified by the detection of asymmetric histone and histone modification patterns around H2A.Z-enriched sites. CATCHprofiles' capability for exhaustive analysis combined with its ease-of-use makes it an invaluable tool for explorative research based on ChIP profiling data. CATCHprofiles and the CATCH algorithm run on all platforms and is available for free through the CATCH website: http://catch.cmbi.ru.nl/. User support is available by subscribing to the mailing list catch-users@bioinformatics.org.

  20. HARDROC, Readout chip of the Digital Hadronic Calorimeter of ILC

    CERN Document Server

    Callier, S; de La Taille, C; Martin-Chassard, N; Seguin-Moreau, N

    2009-01-01

    HARDROC (HAdronic Rpc Detector ReadOut Chip) [1] is the very front end chip designed for the readout of the RPC or Micromegas foreseen for the Digital HAdronic CALorimeter (DHCAL) of the future International Linear Collider. The very fine granularity of the ILC hadronic calorimeters (1cm2 pads) implies a huge number of electronics channels (4 105 /m3) which is a new feature of “imaging” calorimetry. Moreover, for compactness, the chips must be embedded inside the detector making crucial the reduction of the power consumption to 10 μW per channel. This is achieved using power pulsing, made possible by the ILC bunch pattern (1 ms of data acquisition for 199 ms of dead time). HARDROC readout is a semi-digital readout with three thresholds which allows both good tracking and coarse energy measurement, and also integrates on chip data storage. The overall performance of HARDROC will be described with detailed measurements of all the characteristics. Hundreds of chips have indeed been produced and tested befor...

  1. A novel method for fabricating polydimethylsiloxane microfluidic chip master molds

    Institute of Scientific and Technical Information of China (English)

    GAN Ting-ting; XIA Zhi-ning; CHEN Hua; YU Yan-lin

    2009-01-01

    We proposed a novel method of fabricating polydimethylsiloxane (PDMS) microfluidic chip polymer master molds in this paper. The method mainly includes two steps. First, a stainless steel slice was laser etched to form a metal model. Then, the organic solution of poly(methyl methacrylate) (PMMA) was casted onto the metal model to fabricate the PMMA master which subsequently would be used to fabricate PDMS chips. We systematically researched different laser parameters influencing the surface status of microchannels and obtained optimized etching parameters. We investigated and optimized the organic solution composition of PMMA while casting chip masters, and developed a method to form fine polymer masters using two different viscosity solutions to cast the model in turn, and studied the repeatable replication. Then, we investigated physical performance of this chip and evaluated the practicability by analyzing Rhodamine B. Compared with present methods, the proposed method does not need photolithography on photoresistant and chemical etching. The entire fabricating progress is simple, fast, low-cost and can be controlled easily. Only several minutes are required to make a metal model, 3 hours for a PMMA master, and one day for PDMS chips.

  2. Circulating polymerase chain reaction chips utilizing multiple-membrane activation

    Science.gov (United States)

    Wang, Chih-Hao; Chen, Yi-Yu; Liao, Chia-Sheng; Hsieh, Tsung-Min; Luo, Ching-Hsing; Wu, Jiunn-Jong; Lee, Huei-Huang; Lee, Gwo-Bin

    2007-02-01

    This paper reports a new micromachined, circulating, polymerase chain reaction (PCR) chip for nucleic acid amplification. The PCR chip is comprised of a microthermal control module and a polydimethylsiloxane (PDMS)-based microfluidic control module. The microthermal control modules are formed with three individual heating and temperature-sensing sections, each modulating a specific set temperature for denaturation, annealing and extension processes, respectively. Micro-pneumatic valves and multiple-membrane activations are used to form the microfluidic control module to transport sample fluids through three reaction regions. Compared with other PCR chips, the new chip is more compact in size, requires less time for heating and cooling processes, and has the capability to randomly adjust time ratios and cycle numbers depending on the PCR process. Experimental results showed that detection genes for two pathogens, Streptococcus pyogenes (S. pyogenes, 777 bps) and Streptococcus pneumoniae (S. pneumoniae, 273 bps), can be successfully amplified using the new circulating PCR chip. The minimum number of thermal cycles to amplify the DNA-based S. pyogenes for slab gel electrophoresis is 20 cycles with an initial concentration of 42.5 pg µl-1. Experimental data also revealed that a high reproducibility up to 98% could be achieved if the initial template concentration of the S. pyogenes was higher than 4 pg µl-1. The preliminary results of the current paper were presented at the 19th IEEE International Conference on Micro Electro Mechanical Systems (IEEE MEMS 2006), Istanbul, Turkey, 22-26 January, 2006.

  3. PERFORMANCE ENHANCED ROUTER DESIGN FOR NETWORK ON CHIP

    Directory of Open Access Journals (Sweden)

    Anbu chozhan.P

    2013-04-01

    Full Text Available Network on chip is a new paradigm for on chip design that is able to sustain the communication provisions for the SoC with the desired performance. NOC applies networking methodology concepts to system on chip data transfer and it gives noticeable elevation over conventionalbus based communication. NOC router is the backbone of on chip communication which directs the flow of data. In NOC router the arbiter is used during number of inputs request for the similar out port. Arbiter generates the grant based on the priority and previous granted input. For NOC router we have design the efficient round robin arbiter and analyse the power and area. In this paper on chip router is designed with a buffering technique of FWFT based asynchronous FIFO which improves timing and reduce power consumption. The proposed design of router is simulated and synthesized in Xilinx ISE 13.2 and the source code is written in Verilog. Cadence soc encounter of technology ami035 is used to generate layout of router and RTL compiler is used to compute area, power and timing.

  4. KPIX a pixel detector imaging chip

    CERN Document Server

    Cadeddu, S; Caria, M

    2002-01-01

    We present a VLSI custom device, named KPIX, developed in a 0.6 mu m CMOS technology. The circuit is dedicated to readout solid-state detectors covering large areas (on the order of square centimetre) and featuring very small currents. KPIX integrates 1024 channels (current amplifiers) and 8 ADCs on a 15.5x4 mm sup 2 area. Both an analogue and digital readout are allowed, with a 10 bit amplitude resolution. Amplifiers are organized in 8 columns of 128 rows. When choosing the digital or the analogue readout, the complete set of channels can be read out in about 30 ms. The specific design of the amplification cells allows to measure very small input current levels, on the order of fractions of pico-ampere. Power consumption has also been kept at the level of 80 mu W per cell and 150 mW (peak value) in total. The specific chip architecture and geometry allow use of many KPIX circuits together in order to serve a large detector sensitive area. The KPIX structure is presented along with some measurements character...

  5. Scintillation Breakdowns in Chip Tantalum Capacitors

    Science.gov (United States)

    Teverovsky, Alexander

    2008-01-01

    Scintillations in solid tantalum capacitors are momentarily local breakdowns terminated by a self-healing or conversion to a high-resistive state of the manganese oxide cathode. This conversion effectively caps the defective area of the tantalum pentoxide dielectric and prevents short-circuit failures. Typically, this type of breakdown has no immediate catastrophic consequences and is often considered as nuisance rather than a failure. Scintillation breakdowns likely do not affect failures of parts under surge current conditions, and so-called "proofing" of tantalum chip capacitors, which is a controllable exposure of the part after soldering to voltages slightly higher than the operating voltage to verify that possible scintillations are self-healed, has been shown to improve the quality of the parts. However, no in-depth studies of the effect of scintillations on reliability of tantalum capacitors have been performed so far. KEMET is using scintillation breakdown testing as a tool for assessing process improvements and to compare quality of different manufacturing lots. Nevertheless, the relationship between failures and scintillation breakdowns is not clear, and this test is not considered as suitable for lot acceptance testing. In this work, scintillation breakdowns in different military-graded and commercial tantalum capacitors were characterized and related to the rated voltages and to life test failures. A model for assessment of times to failure, based on distributions of breakdown voltages, and accelerating factors of life testing are discussed.

  6. On-Chip Diamond Raman Laser

    CERN Document Server

    Latawiec, Pawel; Burek, Michael J; Hausmann, Birgit J M; Bulu, Irfan; Loncar, Marko

    2015-01-01

    Synthetic single-crystal diamond has recently emerged as a promising platform for Raman lasers at exotic wavelengths due to its giant Raman shift, large transparency window and excellent thermal properties yielding a greatly enhanced figure-of-merit compared to conventional materials. To date, diamond Raman lasers have been realized using bulk plates placed inside macroscopic cavities, requiring careful alignment and resulting in high threshold powers (~W-kW). Here we demonstrate an on-chip Raman laser based on fully-integrated, high quality-factor, diamond racetrack micro-resonators embedded in silica. Pumping at telecom wavelengths, we show Stokes output discretely tunable over a ~100nm bandwidth around 2-{\\mu}m with output powers >250 {\\mu}W, extending the functionality of diamond Raman lasers to an interesting wavelength range at the edge of the mid-infrared spectrum. Continuous-wave operation with only ~85 mW pump threshold power in the feeding waveguide is demonstrated along with continuous, mode-hop-fr...

  7. Congestion Prediction Algorithm for Network on Chip

    Directory of Open Access Journals (Sweden)

    Hua Cai

    2013-07-01

    Full Text Available Network on chip (NoC traffic congestion was one of the important reasons for the data transmission performance degradation. In this paper, we presented a congestion judgment algorithm, which was based on neural network. The congestion control algorithm firstly used the hamming network to compute the NoC’s link buffer congestion state, secondly used the competitive network to find the worst congestion node, and then adopted avoiding congested node  routing policy to improve the NoC’s transmission performance. In this paper, the congestion control algorithm can make the data stream as far as possible evenly distributed in the NoC’s nodes and links and reduce the transmission resource competition. The simulation results showed that the congestion control algorithm could achieve better network throughput and average transmission delay.

  8. Material Biocompatibility for PCR Microfluidic Chips

    KAUST Repository

    Kodzius, Rimantas

    2010-04-23

    As part of the current miniaturization trend, biological reactions and processes are being adapted to microfluidics devices. PCR is the primary method employed in DNA amplification, its miniaturization is central to efforts to develop portable devices for diagnostics and testing purposes. A problem is the PCR-inhibitory effect due to interaction between PCR reagents and the surrounding environment, which effect is increased in high-surface-are-to-volume ration microfluidics. In this study, we evaluated the biocompatibility of various common materials employed in the fabrication of microfluidic chips, including silicon, several kinds of silicon oxide, glasses, plastics, wax, and adhesives. Two-temperature PCR was performed with these materials to determine their PCR-inhibitory effect. In most of the cases, addition of bovine serum albumin effectively improved the reaction yield. We also studied the individual PCR components from the standpoint of adsorption. Most of the materials did not inhibit the DNA, whereas they did show noticeable interaction with the DNA polymerase. Our test, instead of using microfluidic devices, can be easily conducted in common PCR tubes using a standard bench thermocycler. Our data supports an overview of the means by which the materials most bio-friendly to microfluidics can be selected.

  9. Neuromorphic VLSI Models of Selective Attention: From Single Chip Vision Sensors to Multi-chip Systems

    Directory of Open Access Journals (Sweden)

    Giacomo Indiveri

    2008-09-01

    Full Text Available Biological organisms perform complex selective attention operations continuously and effortlessly. These operations allow them to quickly determine the motor actions to take in response to combinations of external stimuli and internal states, and to pay attention to subsets of sensory inputs suppressing non salient ones. Selective attention strategies are extremely effective in both natural and artificial systems which have to cope with large amounts of input data and have limited computational resources. One of the main computational primitives used to perform these selection operations is the Winner-Take-All (WTA network. These types of networks are formed by arrays of coupled computational nodes that selectively amplify the strongest input signals, and suppress the weaker ones. Neuromorphic circuits are an optimal medium for constructing WTA networks and for implementing efficient hardware models of selective attention systems. In this paper we present an overview of selective attention systems based on neuromorphic WTA circuits ranging from single-chip vision sensors for selecting and tracking the position of salient features, to multi-chip systems implement saliency-map based models of selective attention.

  10. Effects of Verticillium dahliae infection on stem-end chip defect development in potatoes (Solanum tuberosum L.)

    Science.gov (United States)

    Potato chips are America's favorite snack food with annual retail sales of over $6 billion. Stem-end chip defect, which is characterized by discoloration of the vasculature and surrounding tissues at the tuber stem end portion of chips, is an important tuber quality concern for US chip production. T...

  11. ChIP on SNP-chip for genome-wide analysis of human histone H4 hyperacetylation

    Directory of Open Access Journals (Sweden)

    Porter Christopher J

    2007-09-01

    Full Text Available Abstract Background SNP microarrays are designed to genotype Single Nucleotide Polymorphisms (SNPs. These microarrays report hybridization of DNA fragments and therefore can be used for the purpose of detecting genomic fragments. Results Here, we demonstrate that a SNP microarray can be effectively used in this way to perform chromatin immunoprecipitation (ChIP on chip as an alternative to tiling microarrays. We illustrate this novel application by mapping whole genome histone H4 hyperacetylation in human myoblasts and myotubes. We detect clusters of hyperacetylated histone H4, often spanning across up to 300 kilobases of genomic sequence. Using complementary genome-wide analyses of gene expression by DNA microarray we demonstrate that these clusters of hyperacetylated histone H4 tend to be associated with expressed genes. Conclusion The use of a SNP array for a ChIP-on-chip application (ChIP on SNP-chip will be of great value to laboratories whose interest is the determination of general rules regarding the relationship of specific chromatin modifications to transcriptional status throughout the genome and to examine the asymmetric modification of chromatin at heterozygous loci.

  12. Optimisation of an oak chips-grape mix maceration process. Influence of chip dose and maceration time.

    Science.gov (United States)

    Gordillo, Belén; Baca-Bocanegra, Berta; Rodriguez-Pulído, Francisco J; González-Miret, M Lourdes; García Estévez, Ignacio; Quijada-Morín, Natalia; Heredia, Francisco J; Escribano-Bailón, M Teresa

    2016-09-01

    Oak chips-related phenolics are able to modify the composition of red wine and modulate the colour stability. In this study, the effect of two maceration techniques, traditional and oak chips-grape mix process, on the phenolic composition and colour of Syrah red wines from warm climate was studied. Two doses of oak chips (3 and 6g/L) at two maceration times (5 and 10days) during fermentation was considered. Changes on phenolic composition (HPLC-DAD-MS), copigmentation/polymerisation (spectrophotometry), and colour (Tristimulus and Differential Colorimetry) were assessed by multivariate statistical techniques. The addition of oak chips at shorter maceration times enhanced phenolic extraction, colour and its stabilisation in comparison to the traditional maceration. On contrast, increasing chip dose in extended maceration time resulted in wines with lighter and less stable colour. Results open the possibility of optimise alternative technological applications to traditional grape maceration for avoiding the common loss of colour of wines from warm climate. PMID:27041323

  13. A functional on-chip pressure generator using solid chemical propellant for disposable lab-on-a-chip.

    Science.gov (United States)

    Hong, Chien-Chong; Murugesan, Suresh; Kim, Sanghyo; Beaucage, Gregory; Choi, Jin-Woo; Ahn, Chong H

    2003-11-01

    This paper presents a functional on-chip pressure generator that utilizes chemical energy from a solid chemical propellant to perform fluidic delivery in applications of plastic-based disposable biochips or lab-on-a-chip systems. In this functional on-chip pressure generator, azobis-isobutyronitrile (AIBN) as the solid chemical propellant is deposited on a microheater using a screen-printing technique, which can heat the AIBN at 70 degrees C to produce nitrogen gas. The output pressure of nitrogen gas, generated from the solid chemical propellant, is adjustable to a desired pressure by controlling the input power of the heater. Using this chemical energy source, the generated pressure depends on the deposited amount of the solid chemical propellant and the temperature of the microheater. Experimental measurements show that this functional on-chip pressure generator can achieve around 3 000 Pa pressure when 189 mJ of energy is applied to heat the 100 microg of AIBN. This pressure can drive 50 nl of water through a microfluidic channel of 70 mm and cross-sectional area of 100 microm x 50 microm. Due to its compact size, ease of fabrication and integration, high reliability (no moving parts), biologically inert gas output along with functionality of gas generation, this pressure generator will be an excellent pressure source for handling the fluids of disposable lab-on-a-chip, biochemical analysis systems or drug delivery systems.

  14. Dry-film polymer waveguide for silicon photonics chip packaging.

    Science.gov (United States)

    Hsu, Hsiang-Han; Nakagawa, Shigeru

    2014-09-22

    Polymer waveguide made by dry film process is demonstrated for silicon photonics chip packaging. With 8 μm × 11.5 μm core waveguide, little penalty is observed up to 25 Gbps before or after the light propagate through a 10-km long single-mode fiber (SMF). Coupling loss to SMF is 0.24 dB and 1.31 dB at the polymer waveguide input and output ends, respectively. Alignment tolerance for 0.5 dB loss increase is +/- 1.0 μm along both vertical and horizontal directions for the coupling from the polymer waveguide to SMF. The dry-film polymer waveguide demonstrates promising performance for silicon photonics chip packaging used in next generation optical multi-chip module.

  15. Readout of TPC Tracking Chambers with GEMs and Pixel Chip

    Energy Technology Data Exchange (ETDEWEB)

    Kadyk, John; Kim, T.; Freytsis, M.; Button-Shafer, J.; Kadyk, J.; Vahsen, S.E.; Wenzel, W.A.

    2007-12-21

    Two layers of GEMs and the ATLAS Pixel Chip, FEI3, have been combined and tested as a prototype for Time Projection Chamber (TPC) readout at the International Linear Collider (ILC). The double-layer GEM system amplifies charge with gain sufficient to detect all track ionization. The suitability of three gas mixtures for this application was investigated, and gain measurements are presented. A large sample of cosmic ray tracks was reconstructed in 3D by using the simultaneous timing and 2D spatial information from the pixel chip. The chip provides pixel charge measurement as well as timing. These results demonstrate that a double GEM and pixel combination, with a suitably modified pixel ASIC, could meet the stringent readout requirements of the ILC.

  16. SNP typing on the NanoChip electronic microarray

    DEFF Research Database (Denmark)

    Børsting, Claus; Sanchez Sanchez, Juan Jose; Morling, Niels

    2005-01-01

    We describe a single nucleotide polymorphism (SNP) typing protocol developed for the NanoChip electronic microarray. The NanoChip array consists of 100 electrodes covered by a thin hydrogel layer containing streptavidin. An electric currency can be applied to one, several, or all electrodes...... at the same time according to a loading protocol generated by the user. Biotinylated deoxyribonucleic acid (DNA) is directed to the pad(s) via the electronic field(s) and bound to streptavidin in the hydrogel layer. Subsequently, fluorescently labeled reporter oligos and a stabilizer oligo are hybridized...... to the bound DNA. Base stacking between the short reporter and the longer stabilizer oligo stabilizes the binding of a matching reporter, whereas the binding of a reporter carrying a mismatch in the SNP position will be relatively weak. Thermal stringency is applied to the NanoChip array according to a reader...

  17. Microfluidic-Based Sample Chips for Radioactive Solutions

    Energy Technology Data Exchange (ETDEWEB)

    Tripp, J. L.; Law, J. D.; Smith, T. E.; Rutledge, V. J.; Bauer, W. F.; Ball, R. D.; Hahn, P. A.

    2014-02-01

    Historical nuclear fuel cycle process sampling techniques required sample volumes ranging in the tens of milliliters. The radiation levels experienced by analytical personnel and equipment, in addition to the waste volumes generated from analysis of these samples, have been significant. These sample volumes also impacted accountability inventories of required analytes during process operations. To mitigate radiation dose and other issues associated with the historically larger sample volumes, a microcapillary sample chip was chosen for further investigation. The ability to obtain microliter volume samples coupled with a remote automated means of sample loading, tracking, and transporting to the analytical instrument would greatly improve analytical efficiency while reducing both personnel exposure and radioactive waste volumes. Sample chip testing was completed to determine the accuracy, repeatability, and issues associated with the use of microfluidic sample chips used to supply µL sample volumes of lanthanide analytes dissolved in nitric acid for introduction to an analytical instrument for elemental analysis.

  18. Researching and implementation of reconfigurable Hash chip based on FPGA

    Institute of Scientific and Technical Information of China (English)

    Yang Xiaohui; Dai Zibin; Liu Yuanfeng; Wang Ting

    2007-01-01

    The reconfigurable cryptographic chip is an integrated circuit that is designed by means of the method of reconfigurable architecture, and is used for encryption and decryption. Many different cipher algorithms can be flexibly implemented with the aid of a reconfigurable cryptographic chip and can be used in many fields. This article takes an example for the SHA-1/224/256 algorithms, and then designs a reconfigurable cryptographic chip based on the thought and method of the reconfigurable architecture. Finally, this paper gives the implementation result based on the FPGA of the family of Stratix II of Altera Corporation, and presents a good research trend for resolving the storage in hardware implementation using FPGAs.

  19. On-chip noninterference angular momentum multiplexing of broadband light.

    Science.gov (United States)

    Ren, Haoran; Li, Xiangping; Zhang, Qiming; Gu, Min

    2016-05-13

    Angular momentum division has emerged as a physically orthogonal multiplexing method in high-capacity optical information technologies. However, the typical bulky elements used for information retrieval from the overall diffracted field, based on the interference method, impose a fundamental limit toward realizing on-chip multiplexing. We demonstrate noninterference angular momentum multiplexing by using a mode-sorting nanoring aperture with a chip-scale footprint as small as 4.2 micrometers by 4.2 micrometers, where nanoring slits exhibit a distinctive outcoupling efficiency on tightly confined plasmonic modes. The nonresonant mode-sorting sensitivity and scalability of our approach enable on-chip parallel multiplexing over a bandwidth of 150 nanometers in the visible wavelength range. The results offer the possibility of ultrahigh-capacity and miniaturized nanophotonic devices harnessing angular momentum division.

  20. The development of taste transduction and taste chip technology

    Institute of Scientific and Technical Information of China (English)

    LI Yan; LIU Qingjun; XU Ying; CAI Hua; QIN Lifeng; WANG Lijiang; WANG Ping

    2005-01-01

    The intrinsic perception process of taste is obviously far less known than those of vision, audition, touch and olfaction. Despite that taste cells utilize a variety of sensory mechanisms to translate plenty of gustatory sensations such as sour, sweet, bitter, salty and umami into cellular signals, gustatory perception mechanisms are still under exploration due to the lack of effective methods on cellular and molecular level. Recently the development of molecular biological and electrophysiological studies has promoted exploration of olfactory and gustatory transduction and coding mechanisms dramatically. Based on the studies of artificial olfaction, artificial taste and cell-based biosensor in our laboratory, this paper reviews the current research on taste transduction mechanism. We introduce the recent advances in cell chip that combined biology with microelectronics, discuss taste cell chip as well as its potential of prospective application in taste transduction mechanism in detail and propose the research trends of taste chip in future.