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Sample records for chinese medicinal plants

  1. The taste sensory evaluation of medicinal plants and Chinese medicines.

    Science.gov (United States)

    Kataoka, Masumi; Tokuyama, Emi; Miyanaga, Yohko; Uchida, Takahiro

    2008-03-01

    The purpose of this study was to investigate the use of the artificial taste sensor in the evaluation of 11 medicinal plants and 10 Chinese medicines with bitter and/or astringent tastes, and to assess the possible application of the sensor in the evaluation of taste and quality control of medicinal products. Aqueous extracts of the six bitter medicinal plants could be classified into three types, and those of the five astringent medicinal plants into two types, on the basis of sensor output pattern profiles. These differences seem to derive from the different structures of the main components. In the principal component analysis of the taste sensor output of 10 Chinese medicines, a new measure developed, the 'Euclidean distance', defined as the distance between a control and the targeted substance on the principal component map. This measure offers a possibility for indicating the different tastes of Chinese medicines. Lastly, we confirmed that berberine adsorption on the surface of the artificial membrane of the taste sensor was of the Langmuir type. The berberine content in extracts of medicinal plants could be evaluated by the taste sensor, and it was shown to be possible to use the taste sensor for the quality control of medicinal plants.

  2. Computational network pharmacological research of Chinese medicinal plants for chronic kidney disease

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    The interaction between drug molecules and target proteins is the basis of pharmacological action.The pharmacodynamic mechanism of Chinese medicinal plants for chronic kidney disease(CKD) was studied by molecular docking and complex network analysis.It was found that the interaction network of components-proteins of Chinese medicinal plants is different from the interaction network of components-proteins of drugs.The action mechanism of Chinese medicinal plants is different from that of drugs.We also found the interaction network of components-proteins of tonifying herbs is different from the interaction network of components-proteins of evil expelling herbs using complex network research approach.It illuminates the ancient classification theory of Chinese medicinal plants.This computational approach could identify the pivotal components of Chinese medicinal plants and their key target proteins rapidly.The results provide data for development of multi-component Chinese medicine.

  3. Book Review on the Illustrated Seeds of Chinese Medicinal Plants

    Institute of Scientific and Technical Information of China (English)

    Guo QS; Wang QY; Liu L; HE Shan-an

    2010-01-01

    @@ Medicinal plants are important source for Oriental and Western medicines. There are more than 500 herbs commonly used today in China, in which near 30% of them are seed medicines and over 65% are propagated from seed.

  4. The carbon isotope ratios and contents of mineral elements in leaves of Chinese medicinal plants

    International Nuclear Information System (INIS)

    Leaf carbon isotope ratios and 13 kinds of mineral elements were measured on 36 species of common Chinese medicinal plants in a subtropical monsoon forest of Ding Hu Shan in Guangdong Province. The .delta.13C value were from -26.4 to -32.6%, indicating that all of the species belonged the photosynthetic C3 types. The relative lower value of δ13C was observed in the life form of shrubs. The contents of 7 elements (N, P, K, Ca, Na Mg, Si) were dependent upon the species, life form, medicinal function and medicinal part. Herb type medicine and the used medicinal part of leaves or whole plant showed higher levels of above elements than the others. Among the nine groups with different medicinal functions, it was found that more nitrogen was in the leaves of medicinal plants for hemophthisis, hypertension and stomachic troubles, more phosphorus and potassium were in the leaves for cancer and snake bite medicines, but more calcium and magnesium were in the leaves for curing rheumatics. Ferric, aluminium and manganese were the main composition of microelements in leaves. There were higher content of ferric in leaves for hemophthisis medicine, higher zinc in leaves for cold and hypertension medicine, and higher Cup in leaves of stomachic medicine. It was suggested that the pattern of mineral elements in leaves of Chinese medicinal plants reflected the different properties of absorption and accumulation. Some additional effect due to the high content of certain element might be associated with the main function of that medicine

  5. Integrated Development of Chinese Herbal Medicine Planting and Tourist Commodities: A Case Study of Green Handmade Soap Development in Shandong Province

    Institute of Scientific and Technical Information of China (English)

    Xiu; LI; Mengxuan; CHEN; Xiaoli; SONG

    2015-01-01

    Combining current situations of Chinese herbal medicine planting industry in Shandong,in line with existing problems of Chinese herbal medicine planting industry,this paper analyzed development prospect of tourist commodity industry in Shandong Province,and came up with actual selection and recommendations for integrated development of Chinese herbal medicine planting and tourist commodities.

  6. TRADITIONAL CHINESE HERBAL MEDICINE

    NARCIS (Netherlands)

    ZHU, YP; WOERDENBAG, HJ

    1995-01-01

    Herbal medicine, acupuncture and moxibustion, and massage and the three major constituent parts of traditional Chinese medicine. Although acupuncture is well known in many Western countries, Chinese herbal medicine, the mos important part of traditional Chinese medicine, is less well known in the We

  7. In silico identification of anti-cancer compounds and plants from traditional Chinese medicine database

    OpenAIRE

    Shao-Xing Dai; Wen-Xing Li; Fei-Fei Han; Yi-Cheng Guo; Jun-Juan Zheng; Jia-Qian Liu; Qian Wang; Yue-Dong Gao; Gong-Hua Li; Jing-Fei Huang

    2016-01-01

    There is a constant demand to develop new, effective, and affordable anti-cancer drugs. The traditional Chinese medicine (TCM) is a valuable and alternative resource for identifying novel anti-cancer agents. In this study, we aim to identify the anti-cancer compounds and plants from the TCM database by using cheminformatics. We first predicted 5278 anti-cancer compounds from TCM database. The top 346 compounds were highly potent active in the 60 cell lines test. Similarity analysis revealed t...

  8. A DNA microarray for the authentication of toxic traditional Chinese medicinal plants.

    Science.gov (United States)

    Carles, Maria; Cheung, Matthew Kin; Moganti, Shanti; Dong, Tina T; Tsim, Karl W; Ip, Nancy Y; Sucher, Nikolaus J

    2005-06-01

    A silicon-based DNA microarray was designed and fabricated for the identification of toxic traditional Chinese medicinal plants. Species-specific oligonucleotide probes were derived from the 5S ribosomal RNA gene of Aconitum carmichaeli, A. kusnezoffi, Alocasia macrorrhiza, Croton tiglium, Datura inoxia, D. metel, D. tatula, Dysosma pleiantha, Dy. versipellis, Euphorbia kansui, Hyoscyamus niger, Pinellia cordata, P. pedatisecta, P. ternata, Rhododendron molle, Strychnos nux-vomica, Typhonium divaricatum and T. giganteum and the leucine transfer RNA gene of Aconitum pendulum and Stellera chamaejasme. The probes were immobilized via dithiol linkage on a silicon chip. Genomic target sequences were amplified and fluorescently labeled by asymmetric polymerase chain reaction. Multiple toxic plant species were identified by parallel genotyping. Chip-based authentication of medicinal plants may be useful as inexpensive and rapid tool for quality control and safety monitoring of herbal pharmaceuticals and neutraceuticals. PMID:15971136

  9. Differentiation of the Chinese minority medicinal plant genus Berchemia spp. by evaluating three candidate barcodes.

    Science.gov (United States)

    Guo, Li-Cheng; Zhao, Ming-Ming; Sun, Wei; Teng, Hong-Li; Huang, Bi-Sheng; Zhao, Xiang-Pei

    2016-01-01

    The genus Berchemia comprises important Chinese plants with considerable medicinal value; however, these plants are often misidentified in the herbal medicinal market. To differentiate the various morphotypes of Berchemia species, a proficient method employing the screening of universal DNA barcodes was used in this work. Three candidate barcoding loci, namely, psbA-trnH, rbcL, and the second internal transcribed spacer (ITS2), were used to identify an effective DNA barcode that can differentiate the various Berchemia species. Additionally, PCR amplification, efficient sequencing, intra- and inter-specific divergences, and DNA barcoding gaps were employed to assess the ability of each barcode to identify these diverse Berchemia plants authentically; the species were differentiated using the Kimura two-parameter and maximum composite likelihood methods. Sequence data analysis showed that the ITS2 region was the most suitable candidate barcode and exhibited the highest interspecific divergence among the three DNA-barcoding sequences. A clear differentiation was observed at the species level, in which a maximum distance of 0.264 was exhibited between dissimilar species. Clustal analysis also demonstrated that ITS2 clearly differentiated the test species in a more effective manner than that with the two other barcodes at both the hybrid and variety levels. Results indicate that DNA barcoding is ideal for species-level identification of Berchemia and provides a foundation for further identification at the molecular level of other Rhamnaceae medicinal plants. PMID:27347459

  10. Instruction to Authors of Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    @@ Chinese Herbal Medicines, an international journal sponsored by the Tianjin Institute of Pharmaceutical Research and Institute of Medicinal Plant Develop-ment. The Journal s purpose is to provide a forum for the studies on Chinese herbal medicines, traditional medicines, and natural products.

  11. Medicinal Plants.

    Science.gov (United States)

    Phillipson, J. David

    1997-01-01

    Highlights the demand for medicinal plants as pharmaceuticals and the demand for health care treatments worldwide and the issues that arise from this. Discusses new drugs from plants, anticancer drugs, antiviral drugs, antimalarial drugs, herbal remedies, quality, safety, efficacy, and conservation of plants. Contains 30 references. (JRH)

  12. In silico identification of anti-cancer compounds and plants from traditional Chinese medicine database

    Science.gov (United States)

    Dai, Shao-Xing; Li, Wen-Xing; Han, Fei-Fei; Guo, Yi-Cheng; Zheng, Jun-Juan; Liu, Jia-Qian; Wang, Qian; Gao, Yue-Dong; Li, Gong-Hua; Huang, Jing-Fei

    2016-05-01

    There is a constant demand to develop new, effective, and affordable anti-cancer drugs. The traditional Chinese medicine (TCM) is a valuable and alternative resource for identifying novel anti-cancer agents. In this study, we aim to identify the anti-cancer compounds and plants from the TCM database by using cheminformatics. We first predicted 5278 anti-cancer compounds from TCM database. The top 346 compounds were highly potent active in the 60 cell lines test. Similarity analysis revealed that 75% of the 5278 compounds are highly similar to the approved anti-cancer drugs. Based on the predicted anti-cancer compounds, we identified 57 anti-cancer plants by activity enrichment. The identified plants are widely distributed in 46 genera and 28 families, which broadens the scope of the anti-cancer drug screening. Finally, we constructed a network of predicted anti-cancer plants and approved drugs based on the above results. The network highlighted the supportive role of the predicted plant in the development of anti-cancer drug and suggested different molecular anti-cancer mechanisms of the plants. Our study suggests that the predicted compounds and plants from TCM database offer an attractive starting point and a broader scope to mine for potential anti-cancer agents.

  13. Ionic liquid-based microwave-assisted extraction of rutin from Chinese medicinal plants.

    Science.gov (United States)

    Zeng, Huan; Wang, Yuzhi; Kong, Jinhuan; Nie, Chan; Yuan, Ya

    2010-12-15

    An ionic liquid-based microwave-assisted extraction (ILMAE) method has been developed for the effective extraction of rutin from Chinese medicinal plants including Saururus chinensis (Lour.) Bail. (S. chinensis) and Flos Sophorae. A series of 1-butyl-3-methylimidazolium ionic liquids with different anions were investigated. The results indicated that the characteristics of anions have remarkable effects on the extraction efficiency of rutin and among the investigated ionic liquids, 1-butyl-3-methylimidazolium bromide ([bmim]Br) aqueous solution was the best. In addition, the ILMAE procedures for the two kinds of medicinal herbs were also optimized by means of a series of single factor experiments and an L(9) (3(4)) orthogonal design. Compared with the optimal ionic liquid-based heating extraction (ILHE), marinated extraction (ILME), ultrasonic-assisted extraction (ILUAE), the optimized approach of ILMAE gained higher extraction efficiency which is 4.879 mg/g in S. chinensis with RSD 1.33% and 171.82 mg/g in Flos Sophorae with RSD 1.47% within the shortest extraction time. Reversed phase high performance liquid chromatography (RP-HPLC) with ultraviolet detection was employed for the analysis of rutin in Chinese medicinal plants. Under the optimum conditions, the average recoveries of rutin from S. chinensis and Flos Sophorae were 101.23% and 99.62% with RSD lower than 3%, respectively. The developed approach is linear at concentrations from 42 to 252 mg L(-1) of rutin solution, with the regression coefficient (r) at 0.99917. Moreover, the extraction mechanism of ILMAE and the microstructures and chemical structures of the two researched samples before and after extraction were also investigated. With the help of LC-MS, it was future demonstrated that the two researched herbs do contain active ingredient of rutin and ionic liquids would not influence the structure of rutin.

  14. Evaluation of four commonly used DNA barcoding Loci for chinese medicinal plants of the family schisandraceae.

    Directory of Open Access Journals (Sweden)

    Jian Zhang

    Full Text Available Many species of Schisandraceae are used in traditional Chinese medicine and are faced with contamination and substitution risks due to inaccurate identification. Here, we investigated the discriminatory power of four commonly used DNA barcoding loci (ITS, trnH-psbA, matK, and rbcL and corresponding multi-locus combinations for 135 individuals from 33 species of Schisandraceae, using distance-, tree-, similarity-, and character-based methods, at both the family level and the genus level. Our results showed that the two spacer regions (ITS and trnH-psbA possess higher species-resolving power than the two coding regions (matK and rbcL. The degree of species resolution increased with most of the multi-locus combinations. Furthermore, our results implied that the best DNA barcode for the species discrimination at the family level might not always be the most suitable one at the genus level. Here we propose the combination of ITS+trnH-psbA+matK+rbcL as the most ideal DNA barcode for discriminating the medicinal plants of Schisandra and Kadsura, and the combination of ITS+trnH-psbA as the most suitable barcode for Illicium species. In addition, the closely related species Schisandra rubriflora Rehder & E. H. Wilson and Schisandra grandiflora Hook.f. & Thomson, were paraphyletic with each other on phylogenetic trees, suggesting that they should not be distinct species. Furthermore, the samples of these two species from the southern Hengduan Mountains region formed a distinct cluster that was separated from the samples of other regions, implying the presence of cryptic diversity. The feasibility of DNA barcodes for identification of geographical authenticity was also verified here. The database and paradigm that we provide in this study could be used as reference for the authentication of traditional Chinese medicinal plants utilizing DNA barcoding.

  15. Screening of Epstein—Barr Virus Early Antigen Expression Inducers from Chinese Medicinal Herbs and Plants

    Institute of Scientific and Technical Information of China (English)

    ZENGY; ZHONGJian-Ming; 等

    1994-01-01

    Ethern extracts of 1693 Chinese medicinal herbs and plants from 268 families were studied for the induction of Epstein-Barr viral(EVB)early antigen(EA)expression in the Raji cell line.Fifty-two from 18 families were found to have inducing activity.Twenty-five and seven of them were from Euphorbiaceae and Thymelaeaceae,respactively.Some of them,such as Croton tiglium,Euphorbia kansui,Daphne genkwa,Wikstroemia chamaedaphen,Wikstroemia indica,Prunus mandshurica Koehne and Achyranthes bidentata are commonly used drugs.The significance of these herbs in the activation of EBV in vivo and their relation to the development of nasopharyngeal carcinoma were discussed.

  16. Determination of glucosinolates in 19 Chinese medicinal plants with spectrophotometry and high-pressure liquid chromatography.

    Science.gov (United States)

    Hu, Ye; Liang, Hao; Yuan, Qipeng; Hong, Yuancheng

    2010-08-01

    Glucosinolates were evaluated in 19 traditional Chinese medicinal plants involved in seven different families: Brassicaceae, Capparaceae, Euphorbiaceae, Phytolaccaceae, Tropaeolaceae, Caricaceae and Rubiaceae. The total glucosinolate contents were determined by spectrophotometry. Results showed that the high contents of total glucosinolates were found in some herbs of Brassicaceae, Capparaceae and Euphorbiaceae families, while low total glucosinolate contents were observed in two Rubiaceae herbs. In addition, eight glucosinolates (glucoraphanin, glucoraphenin, sinalbin, sinigrin, progoitrin, 4-hydroglucobrassicin, glucoiberin and glucoibervirin) in these herbs were measured using HPLC, and the data showed that individual glucosinolates and their contents varied at different degrees among the distinct species. The highest contents of cancer-protective compounds were found in the seeds of Raphanus sativus L. (glucoraphenin), Sinapis alba (sinalbin) and Phyllanthus emblica L. (sinigrin). PMID:20645206

  17. Deep Sequencing of Plant and Animal DNA Contained within Traditional Chinese Medicines Reveals Legality Issues and Health Safety Concerns

    OpenAIRE

    Megan L Coghlan; James Haile; Jayne Houston; Dáithí C. Murray; White, Nicole E.; Paula Moolhuijzen; Bellgard, Matthew I.; Michael Bunce

    2012-01-01

    Traditional Chinese medicine (TCM) has been practiced for thousands of years, but only within the last few decades has its use become more widespread outside of Asia. Concerns continue to be raised about the efficacy, legality, and safety of many popular complementary alternative medicines, including TCMs. Ingredients of some TCMs are known to include derivatives of endangered, trade-restricted species of plants and animals, and therefore contravene the Convention on International Trade in En...

  18. Species identification of Chinese medicinal plant Fallopia multiflora (Thunb.) Haraldson by suppression subtraction hybridization.

    Science.gov (United States)

    Zheng, Chuan-Jin; Zhao, Shu-Jin; Shao, Li

    2014-01-01

    Fallopia multiflora (Thunb.) Haraldson, a traditional Chinese medicinal plant, has been extensively used in preparations of herbal medicine, health products and personal hygiene products. However, the clinical safety and efficiency of F. multiflora (Thunb.) Haraldson is impaired because of the existence of various adulterants. In this study, genomic DNA (gDNA) suppression subtraction hybridization (SSH) was used to authenticate F. multiflora (Thunb.) Haraldson from its adulterants. First, differential gDNA fragments between F. multiflora (Thunb.) Haraldson and its most closely related species F. multiflora var. ciliinervis (Nakai) Yonek. & H. Ohashi by SSH were identified. The differential fragments were then hybridized with arrays constructed from multiple whole genomes of several species (adulterants and/or closely related plants) to screen for the unique gDNA fragments representing F. multiflora (Thunb.) Haraldson. The unique gDNA fragments could be used to design species-specific primers for the identification of F. multiflora (Thunb.) Haraldson. Using SSH, we obtained four differential gDNA fragments, and four pairs of primers were designed. The designed primers could differentiate F. multiflora (Thunb.) Haraldson from its adulterants and/or closely related species via PCR. The results confirmed that the SSH is an efficient method for screening and designing species-specific primers. PMID:23633031

  19. [Application prospect and expectation of fungistatic agents of plants in preservation of Chinese herbal medicines].

    Science.gov (United States)

    Li, Yan-jun; Kong, Wei-jun; Hu, Yi-chen; Zhao, Lian-hua; Yang, Shi-hai; Yang, Mei-hua

    2015-10-01

    During the process of growth, harvesting, transportation, processing and storage, Chinese herbal medicines (CHMs) can be easily contaminated by fungi and their metabolites like mycotoxins, which not only express negative effects on the quality and safety of CHMs and their processed products, but also pose great threats to human health. Now, some chemical synthetic fungicides have been frequently used to control the growth of fungi and accumulation of mycotoxins in the preservation of CHMs. However, the concentration and type of chemical fungicides allowed for postharvest application are restricted due to the disadvantages of their high residual toxicity, long degradation period and pollution to the environment and so on. Therefore, it is critical to research and develop some highly effective, safe and non-toxic, natural, environment-friendly fungistatic agents from plants to prevent CHMs from being contaminated by fungi and mycotoxins. The paper reviews mycotoxins and their harmfulness, the effective compounds of fungistatic plants as well as the antifungal mechanism to provide scientific evidences for developing novel and effective fungistatic agents plants. Then, the application prospect of fungistatic agents from plants in the preservation of CHMs was discussed.

  20. Diversity of Pharmacological Properties in Chinese and European Medicinal Plants: Cytotoxicity, Antiviral and Antitrypanosomal Screening of 82 Herbal Drugs

    OpenAIRE

    Thomas Efferth; Marin, Jose J. G.; Stefan Kahl; Dorothea Kaufmann; Ashour, Mohamed L; Blazquez, Alba G; Romero, Marta R.; Michael Wink; Florian Herrmann

    2011-01-01

    In an extensive screening, the antiviral, antitrypanosomal and anticancer properties of extracts from 82 plants used in traditional Chinese medicine and European phytomedicine were determined. Several promising plants that were highly effective against hepatitis B virus (HBV), bovine viral diarrhoea virus (BVDV)—a flavivirus used here as a surrogate in vitro model of hepatitis C virus, trypanosomes (Trypanosoma brucei brucei) and several cancer cell lines were identified. Six aqueous extracts...

  1. History of Chinese medicinal wine.

    Science.gov (United States)

    Xia, Xun-Li

    2013-07-01

    Chinese medicinal wine is one type of a favorable food-drug product invented by Chinese ancestors for treating and preventing diseases, promoting people's health and corporeity, and enriching people's restorative culture. In the course of development of the millenary-old Chinese civilization, Chinese medicinal wine has made incessant progress and evolution. In different historical periods, Chinese medicinal wine presented different characteristics in basic wine medical applications, prescriptions, etc. There are many medical and Materia Medica monographs which have systemically and specifically reported on Chinese medicinal wine in past Chinese dynasties. By studying leading medical documents, this article made an outline review on the invention, development, and characteristics of Chinese medicinal wine.

  2. Molecular screening of Chinese medicinal plants for progestogenic and anti-progestogenic activity

    Indian Academy of Sciences (India)

    H M Manir Ahmed; Jan-Ying Yeh; Yi-Chia Tang; Winston Teng-Kuei Cheng; Bor-Rung Ou

    2014-06-01

    Estrogen and progestins have adverse effects, and many of these adverse effects are caused by progestins. Due to this, many women choose to use botanical alternatives for hormone replacement therapy, which does not trigger steroidogenic properties. Therefore, it is necessary to screen these herbs for progestogenic and anti-progestogenic properties. Extract of 13 Chinese medicinal plants were analysed for progestogenic and anti-progestogenic activities by using progesterone response element-driven luciferase reporter gene bioassay. MTT assay was carried out to investigate the cytotoxic effect of herb extract on PAE cells. Among the 13 herbs, Dipsacus asperoides extract exhibited progestogenic activity, and 10 species – Cortex eucommiae, Folium artemisiae argyi, Glycyrrhiza uralensis, Angelica sinensis, Atractylodes macrocephala koidz, Scutellaria baicalensis, Cuscuta chinensis, Euscaphis japonica, Ailanthus altissima, and Dioscorea opposita – were recognized to have anti-progestogenic like activities. Extract of Dipsacus asperoides demonstrated dose-dependent progestogenic activity, and the progestogenic activity of 100 g/mL extracts was equivalent to 31.45 ng/mL progesterone activity. Herbs extracts that exhibited anti-progestogenic-like activity also inhibited the 314.46 ng/mL progesterone activity in a dose-response manner. None of the herb extracts shown significant toxic effect on PAE cells at 40–100 g/mL compared to control. This discovery will aid selection of suitable herbs for hormone replacement therapy.

  3. Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    2009013 Clinical observation on treatment of active rheumatoid arthritis with Chinese herbal medicine. SHENG Zhenghe(盛正和), et al.Dept TCM, 5th Affili Hosp, Guangxi Med Univ, Guangxi 545001. Chin J Integr Tradit West Med 2008;28(11):990-993. Objective To study the efficacy and safety of Chinese drugs for expelling evil-wind, removing dampness, promoting blood circulation and invigorating yin in treating active rheumatoid arthritis (RA).

  4. Transmitting Chinese Medicine

    Science.gov (United States)

    Scheid, Volker

    2015-01-01

    Historians of Chinese medicine acknowledge the plurality of Chinese medicine along both synchronic and diachronic dimensions. Yet, there remains a tendency to think of tradition as being defined by some unchanging features. The Chinese medical body is a case in point. This is assumed to have been formalised by the late Han dynasty around a system of internal organs, conduits, collaterals, and associated body structures. Although criticism was voiced from time to time, this body and the micro/macrocosmic cosmological resonances that underpin it are seen to persist until the present day. I challenge this view by attending to attempts by physicians in China and Japan in the period from the mid 16th to the late 18th century to reimagine this body. Working within the domain of cold damage therapeutics and combining philological scholarship, empirical observations, and new hermeneutic strategies these physicians worked their way towards a new territorial understanding of the body and of medicine as warfare that required an intimate familiarity with the body’s topography. In late imperial China this new view of the body and medicine was gradually re-absorbed into the mainstream. In Japan, however, it led to a break with this orthodoxy that in the Republican era became influential in China once more. I argue that attending further to the innovations of this period from a transnational perspective - commonly portrayed as one of decline - may help to go beyond the modern insistence to frame East Asian medicines as traditional. PMID:26869864

  5. History of Chinese medicinal wine.

    Science.gov (United States)

    Xia, Xun-Li

    2013-07-01

    Chinese medicinal wine is one type of a favorable food-drug product invented by Chinese ancestors for treating and preventing diseases, promoting people's health and corporeity, and enriching people's restorative culture. In the course of development of the millenary-old Chinese civilization, Chinese medicinal wine has made incessant progress and evolution. In different historical periods, Chinese medicinal wine presented different characteristics in basic wine medical applications, prescriptions, etc. There are many medical and Materia Medica monographs which have systemically and specifically reported on Chinese medicinal wine in past Chinese dynasties. By studying leading medical documents, this article made an outline review on the invention, development, and characteristics of Chinese medicinal wine. PMID:21853349

  6. Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns.

    Directory of Open Access Journals (Sweden)

    Megan L Coghlan

    Full Text Available Traditional Chinese medicine (TCM has been practiced for thousands of years, but only within the last few decades has its use become more widespread outside of Asia. Concerns continue to be raised about the efficacy, legality, and safety of many popular complementary alternative medicines, including TCMs. Ingredients of some TCMs are known to include derivatives of endangered, trade-restricted species of plants and animals, and therefore contravene the Convention on International Trade in Endangered Species (CITES legislation. Chromatographic studies have detected the presence of heavy metals and plant toxins within some TCMs, and there are numerous cases of adverse reactions. It is in the interests of both biodiversity conservation and public safety that techniques are developed to screen medicinals like TCMs. Targeting both the p-loop region of the plastid trnL gene and the mitochondrial 16S ribosomal RNA gene, over 49,000 amplicon sequence reads were generated from 15 TCM samples presented in the form of powders, tablets, capsules, bile flakes, and herbal teas. Here we show that second-generation, high-throughput sequencing (HTS of DNA represents an effective means to genetically audit organic ingredients within complex TCMs. Comparison of DNA sequence data to reference databases revealed the presence of 68 different plant families and included genera, such as Ephedra and Asarum, that are potentially toxic. Similarly, animal families were identified that include genera that are classified as vulnerable, endangered, or critically endangered, including Asiatic black bear (Ursus thibetanus and Saiga antelope (Saiga tatarica. Bovidae, Cervidae, and Bufonidae DNA were also detected in many of the TCM samples and were rarely declared on the product packaging. This study demonstrates that deep sequencing via HTS is an efficient and cost-effective way to audit highly processed TCM products and will assist in monitoring their legality and safety

  7. TRADITIONAL CHINESE MEDICINE

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930433 A study on relationship between hy-pothyroidism and deficiency of kidney YANG.ZHA Lianglun(查良伦),et al.lnstit Integr TCM& West Med,Shanghai Med Univ,Shanghai,200040.Chin J Integr Tradit & West Med 1993;13(4):202—204.Thirty—two cases of hypothyroidism causedby various factors were treated for one year withChinese medicinal herbs preparation“Shen Lutablet”(SLT)to warm and reinforce the KidneyYang.34 normal persons were studied as a con-trol group.After treatment with SLT,the clini-cal symptoms of hypothyroidism were markedlyimproved.Average serum concentration of totalT3,T4 increased significantly from 67.06±4.81

  8. Diversity of Pharmacological Properties in Chinese and European Medicinal Plants: Cytotoxicity, Antiviral and Antitrypanosomal Screening of 82 Herbal Drugs

    Directory of Open Access Journals (Sweden)

    Thomas Efferth

    2011-09-01

    Full Text Available In an extensive screening, the antiviral, antitrypanosomal and anticancer properties of extracts from 82 plants used in traditional Chinese medicine and European phytomedicine were determined. Several promising plants that were highly effective against hepatitis B virus (HBV, bovine viral diarrhoea virus (BVDV—a flavivirus used here as a surrogate in vitro model of hepatitis C virus, trypanosomes (Trypanosoma brucei brucei and several cancer cell lines were identified. Six aqueous extracts from Celosia cristata, Ophioglossum vulgatum, Houttuynia cordata, Selaginella tamariscina, Alpinia galanga and Alpinia oxyphylla showed significant antiviral effects against BVDV without toxic effects on host embryonic bovine trachea (EBTr cells, while Evodia lepta, Hedyotis diffusa and Glycyrrhiza spp. demonstrated promising activities against the HBV without toxic effects on host human hepatoblastoma cells transfected with HBV-DNA (HepG2 2.2.15 cells. Seven organic extracts from Alpinia oxyphylla, Coptis chinensis, Kadsura longipedunculata, Arctium lappa, Panax ginseng, Panax notoginseng and Saposhnikovia divaricata inhibited T. b. brucei. Moreover, among fifteen water extracts that combined high antiproliferative activity (IC50 0.5–20 µg/mL and low acute in vitro toxicity (0–10% reduction in cell viability at IC50, Coptis chinensis presented the best beneficial characteristics. In conclusion, traditional herbal medicine from Europe and China still has a potential for new therapeutic targets and therapeutic applications.

  9. Extracts from Traditional Chinese Medicinal Plants Inhibit Acetylcholinesterase, a Known Alzheimer’s Disease Target

    Directory of Open Access Journals (Sweden)

    Dorothea Kaufmann

    2016-08-01

    Full Text Available Inhibition of acetylcholinesterase (AChE is a common treatment for early stages of the most general form of dementia, Alzheimer’s Disease (AD. In this study, methanol, dichloromethane and aqueous crude extracts from 80 Traditional Chinese Medical (TCM plants were tested for their in vitro anti-acetylcholinesterase activity based on Ellman’s colorimetric assay. All three extracts of Berberis bealei (formerly Mahonia bealei, Coptis chinensis and Phellodendron chinense, which contain numerous isoquinoline alkaloids, substantially inhibited AChE. The methanol and aqueous extracts of Coptis chinensis showed IC50 values of 0.031 µg/mL and 2.5 µg/mL, therefore having an up to 100-fold stronger AChE inhibitory activity than the already known AChE inhibitor galantamine (IC50 = 4.33 µg/mL. Combinations of individual alkaloids berberine, coptisine and palmatine resulted in a synergistic enhancement of ACh inhibition. Therefore, the mode of AChE inhibition of crude extracts of Coptis chinensis, Berberis bealei and Phellodendron chinense is probably due to of this synergism of isoquinoline alkaloids. All extracts were also tested for their cytotoxicity in COS7 cells and none of the most active extracts was cytotoxic at the concentrations which inhibit AChE. Based on these results it can be stated that some TCM plants inhibit AChE via synergistic interaction of their secondary metabolites. The possibility to isolate pure lead compounds from the crude extracts or to administer these as nutraceuticals or as cheap alternative to drugs in third world countries make TCM plants a versatile source of natural inhibitors of AChE.

  10. Problems and Countermeasures on Chinese Herbal Medicine Planting%我国中药材种植存在的问题及对策

    Institute of Scientific and Technical Information of China (English)

    蔡宏伟

    2016-01-01

    中药材种植业处于中医药产业链的最前端,对我国中药材的品质有着直接影响,进而有可能影响到中医疗效和中医药的继承与发展。在我国中药材的种植中,存在着监管效率不高,盲目仓促引种驯化,缺乏全面规划和市场预测,种子种苗问题突出,种植过程缺乏科学化、规范化管理等问题。应当做好监管工作,科学合理引种驯化,做好全面规划,做好种子种苗相关工作以及加强中药材种植过程监管。%The Chinese herbal medicine planting is the first part of the industry chain of the traditional Chinese medical science and Chinese herbal medicines, which has a direct influence on the quality of Chinese herbal medicines and may have an influence on curative effects of tradi-tional Chinese medicine and the inheriting and development.In Chinese herbal medicine planting, there are many problems, such as inefficient supervision, a lack of scientific planning, outstanding problems on seeds and planting stock, a lack of scientific and standardized supervision.We suggest that supervision subjects should be definite and supervision should be professional to enhance the efficiency, overall planning should be made, introduction and domestication should be scientific and reasonable, work of seeds and stock should be improved and supervision of the whole planting procedure should be strengthened.

  11. Antioxidant and anti-inflammatory activities of selected Chinese medicinal plants and their relation with antioxidant content

    Directory of Open Access Journals (Sweden)

    Ravipati Anjaneya S

    2012-10-01

    Full Text Available Abstract Background The main aim of this study is to evaluate the antioxidant and anti-inflammatory properties of forty four traditional Chinese medicinal herbal extracts and to examine these activities in relation to their antioxidant content. Methods The antioxidant activities were investigated using DPPH radical scavenging method and yeast model. The anti-inflammatory properties of the herbal extracts were evaluated by measuring their ability to inhibit the production of nitric oxide and TNF-α in RAW 264.7 macrophages activated by LPS and IFN- γ, respectively. The cytotoxic effects of the herbal extracts were determined by Alomar Blue assay by measuring cell viability. In order to understand the variation of antioxidant activities of herbal extracts with their antioxidant contents, the total phenolics, total flavonoids and trace metal (Mg, Mn, Cu, Zn, Se and Mo quantities were estimated and a correlation analysis was carried out. Results Results of this study show that significant levels of phenolics, flavonoids and trace metal contents were found in Ligustrum lucidum, Paeonia suffuticosa, Salvia miltiorrhiza, Sanguisorba officinalis, Spatholobus suberectus, Tussilago farfara and Uncaria rhyncophylla, which correlated well with their antioxidant and anti-inflammatory activities. Some of the plants displayed high antioxidant and anti-inflammatory activities but contained low levels of phenolics and flavonoids. Interestingly, these plants contained significant levels of trace metals (such as Zn, Mg and Se which are likely to be responsible for their activities. Conclusions The results indicate that the phenolics, flavonoids and trace metals play an important role in the antioxidant activities of medicinal plants. Many of the plants studied here have been identified as potential sources of new antioxidant compounds.

  12. Development and Characterization of EST-SSR Markers in the Chinese Medicinal Plant Callerya speciosa (Fabaceae

    Directory of Open Access Journals (Sweden)

    Li Li

    2013-06-01

    Full Text Available Premise of the study: The first microsatellite primers were developed for Callerya speciosa, an important traditional medicinal plant with island-mainland distributions in China, to further investigate its genetic variability and population structure. Methods and Results: The microsatellite-containing sequences were selected from a cDNA library of C. speciosa. In total, 58 primer pairs were designed, and 25 of the corresponding loci showed clear amplification. Polymorphisms were assessed in two different natural populations. The mean number of alleles per locus ranged from two to nine. Observed and expected heterozygosity per loci ranged from 0.067 to 0.938 and 0.064 to 0.836, respectively. One out of 25 loci showed departure from Hardy–Weinberg equilibrium expectations in both populations, and three pairs of loci showed significant linkage disequilibrium after Bonferroni correction. Conclusions: These microsatellite markers will be useful tools for genetic and conservation studies and to understand the evolutionary processes in Callerya species.

  13. [Application of magnetic materials in analysis on Chinese herb medicines].

    Science.gov (United States)

    Xu, Li-Wei; Wang, Jiu-Rong; Han, Xue-Feng

    2012-12-01

    China is the cradle of Chinese herb medicines,with rich plant resources. However, traditional processing methods have many disadvantages, such as high comsumption of organic solvent, long extraction time and high loss of effective constituents. For the purpose of rational use of Chinese herb medicines and accurate analysis on their constituents,the sample pre-treatment method with magnetic nanoparticles as the carrier brought new opportunities in recent years. after consulting literatures,the essay summarizes traditional extraction methods of Chinese herb medicines, characteristics of magnetic materials and their application in the analysis on Chinese herb medicines. PMID:23477130

  14. Traditional Chinese medicine for primary liver cancer

    Institute of Scientific and Technical Information of China (English)

    1998-01-01

    @@ Further progress has been made in the traditional Chinese medicine for primary liver cancer over the past few years, especially in the research of traditional Chinese medicine (TCM) treatment principle, improvement of therapeutic results and prolonging the survival.

  15. Clinical Service of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ The clinical practice of traditional Chinese medicine (TCM) faces three major challenges:(1)How to enhance its contribution on overall medical service quality? (2) How to best address the unmet medical needs in the contemporary society? (3)How to guarantee that the traditional perspective for disease diagnosis and treatment not be neglected in clinical practice?

  16. Selection for high oridonin yield in the Chinese medicinal plant Isodon (Lamiaceae using a combined phylogenetics and population genetics approach.

    Directory of Open Access Journals (Sweden)

    Eric S J Harris

    Full Text Available Oridonin is a diterpenoid with anti-cancer activity that occurs in the Chinese medicinal plant Isodon rubescens and some related species. While the bioactivity of oridonin has been well studied, the extent of natural variation in the production of this compound is poorly known. This study characterizes natural variation in oridonin production in order to guide selection of populations of Isodon with highest oridonin yield. Different populations of I. rubescens and related species were collected in China, and their offspring were grown in a greenhouse. Samples were examined for oridonin content, genotyped using 11 microsatellites, and representatives were sequenced for three phylogenetic markers (ITS, rps16, trnL-trnF. Oridonin production was mapped on a molecular phylogeny of the genus Isodon using samples from each population as well as previously published Genbank sequences. Oridonin has been reported in 12 out of 74 species of Isodon examined for diterpenoids, and the phylogeny indicates that oridonin production has arisen at least three times in the genus. Oridonin production was surprisingly consistent between wild-collected parents and greenhouse-grown offspring, despite evidence of gene flow between oridonin-producing and non-producing populations of Isodon. Additionally, microsatellite genetic distance between individuals was significantly correlated with chemical distance in both parents and offspring. Neither heritability nor correlation with genetic distance were significant when the comparison was restricted to only populations of I. rubescens, but this result should be corroborated using additional samples. Based on these results, future screening of Isodon populations for oridonin yield should initially prioritize a broad survey of all species known to produce oridonin, rather than focusing on multiple populations of one species, such as I. rubescens. Of the samples examined here, I. rubescens or I. japonicus from Henan province

  17. TRIBAL MEDICINAL PLANTS OF CHITTOOR

    OpenAIRE

    Vedavathy, S.; Sudhakar, A; Mrdula, V.

    1997-01-01

    Medicinal plants used in tribal medicine from chittoor district have been surveyed and documented systematically. The paper deals with 202 medicinal plants, indexed along with important tribal applications for the cure of various ailments.

  18. Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    2007134 Clinical study on "Jin′s three-needling" in the treatment of generalized anxiety disorder. LUO Wenzheng(罗文政), et al. Coll Acupunct & Massage, Guangzhou TCM Univ, Guangzhou 510405. Chin J Integr Trad & West Med 2007;27(3):201-203. Objective To study the clinical effect of "Jin′s three-needling" in the treatment of generalized anxiety disorder. Methods Fifty-eight patients with generalized anxiety were randomly assigned to two groups equally. the medication group treated with anti-anxiety drugs and the acupuncture group with "Jin′s three-needling". The treatment course was 6 weeks. The clinical effects were evaluated with Hamilton anxiety scale (HAMA), clinical global impression (CGI), and treatment emergent symptom scale (TESS) before treatment and at the end of 2nd, 4th, 6th week of the treatment course. The concentration of 5-hydroxytryptamine (5-HT) in platelet, and plasma levels of corticosterone (CS) and adrenocorticotropic hormone (ACTH) were measured with high performance liquid chromatography-electrochemical detection (HPLC-ED) method before and after treatment. Results The clinical effects in the two groups were equivalent, while the adverse reaction found in the acupuncture group was less than that in the medication group (P<0.05). The platelet concentration of 5-HT and plasma ACTH level decreased significantly in both groups after treatment with insignificant difference between the group (P<0.05). The plasma CS level had no obvious change in the two groups after treatment as compared with that before treatment.Conclusion "Jin′s three-needling" shows similar curative effect on generalized anxiety to routine Western medicine but with less adverse reaction, which may be realized through regulating the platelet 5-HT concentration and plasma ACTH level.

  19. AN UPDATED REVIEW ON ANTHELMINTIC MEDICINAL PLANTS

    Directory of Open Access Journals (Sweden)

    Raj Kumar

    2012-02-01

    Full Text Available Medicinal plants are part and parcel of human society to combat diseases, from the dawn of civilization. There exists a plethora of knowledge, information and benefits of herbal drugs in our ancient literature of Ayurvedic (Traditional Indian Medicine, Siddha, Unani and Chinese medicine. According to the World Health Organization, 2003 about 80 % of the population of developing countries being unable to afford pharmaceutical drugs rely on traditional medicines, mainly plant based, to sustain their primary health care needs. Herbal medicines are in great demand in the developed as well as developing countries for primary healthcare because of their wide biological and medicinal activities, higher safety margins and lesser costs. In this review we have enlisted the updated anthelmintic medicinal plants which are used as good alternatives for the traditional allopathic anthelmintic agents.

  20. Medicinal plants of Kermanshah province

    OpenAIRE

    Mostafa Nemati Paykani; Nastaran Jalilian

    2012-01-01

    In order to collect and determine medicinal plants of Kermanshah province, at first a list of medicinal plants and their localities was prepared based on the floristic list of the Kermanshah province mentioned as medicinal plants in the related references. Then, stands of the mentioned medicinal plants were referred according to the topographic maps and the extracted localities and after collecting medicinal plant specimens, herbarium specimens were prepared based on the traditional taxonomic...

  1. Chinese integrative medicine:inclusion of a Chinese medicine programme in a conventional medical institute

    Institute of Scientific and Technical Information of China (English)

    Hai-Yong Chen; Yibin Feng; Lixing Lao

    2014-01-01

    To meet community demands with optimal Chinese and conventional medical treatment, the University of Hong Kong is promoting integrative medicine by developing Chinese medicine programmes that train students of both Western and Chinese medicine. The programmes emphasize multi-disciplinary training and interaction between the two therapeutic approaches, enabling students to establish reliable, consistent, and respectful mutual cooperation in their future careers.

  2. Chinese traditional medicine for induction of ovulation

    Institute of Scientific and Technical Information of China (English)

    肖碧莲

    2003-01-01

    This is a review paper of some effective recipes of Chinese traditional medicine usedin ovulation induction and treatment of gynecological diseases. Some clinical results bygynecologists using Chinese traditional medicine in combination with western medicineand results from research on traditional medicine with modern technology are presented.A list of frequently used traditional medicine for ovulation induction are selected from the famous Compendium of Materica Medica(本草纲目)by Li Shi-zhen(李时珍).

  3. Plants and Medicinal Chemistry

    Science.gov (United States)

    Bailey, D.

    1977-01-01

    This is the first of two articles showing how plants that have been used in folk medicine for many centuries are guiding scientists in the design and preparation of new and potent drugs. Opium and its chemical derivatives are examined at length in this article. (Author/MA)

  4. Chinese medicinal herbs for chronic hepatitis B

    DEFF Research Database (Denmark)

    Liu, J; McIntosh, H; Lin, Haili

    2001-01-01

    Chronic hepatitis B is a serious health problem worldwide. Chinese medicinal herbs are widely used for treatment of chronic hepatitis B in China and many clinical trials have been conducted. This systematic review is to assess the efficacy and safety of Chinese medicinal herbs for chronic hepatitis...

  5. Approaches in Treating AIDS with Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    吕维柏

    2002-01-01

    @@ Editorial: AIDS is the archenemy of mankind, it also threatened Chinese people seriously. Although anti-retroviral drugs are effective, yet too expensive, the majority of 600 000 Chinese patients can't afford to purchase and use them. Decades ago, some scientists were trying to use Chinese Medicine in treating AIDS, experienc e gained but problems also exposed concerning strategy of research, methodol ogy, racial difference, Chinese drugs screening, integrative Chinese and western medicine, HIV and immunity, etc., sustained and integrative effort would bring safe, effective, and affordable drugs for the fatal pandemic all over the world

  6. An ethnopharmacological investigation of medicinal Salvia plants (Lamiaceae) in China

    OpenAIRE

    Minhui Li; Qianquan Li; Chunhong Zhang; Na Zhang; Zhanhu Cui; Luqi Huang; Peigen Xiao

    2013-01-01

    In China, over 40 species of the genus Salvia have been used as medicinal plants for various diseases, some for thousands of years. Recently, research has focused on the biological activities of Salvia medicinal plants used in traditional chinese medicine (TCM). However, to date a scientific survey of the genus Salvia in China has not been carried out. In this paper, we report the results of 10 field surveys of Salvia medicinal plants collected in 17 provinces including detailed information o...

  7. Introduction of Institute of Medicinal Plant Development

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Institute of Medicinal Plant Development (IMPLAD), affiliated with the Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), was established in August 1983. IMPLAD, headquartered in the Zhongguancun Scientific and Technical Zone, Beijing, China, owns three branch institutes with total over 333 hectares of land in the subtropical regions of southern China, located in

  8. Traditional Chinese medicine in treatment of opiate addiction

    Institute of Scientific and Technical Information of China (English)

    Jie SHI; Yan-li LIU; Yu-xia FANG; Guo-zhu XU; Hai-fen ZHAI; Lin LU

    2006-01-01

    Traditional Chinese medicine (TCM) includes Chinese medicine and acupuncture. Chinese medicine consists of natural products including plants, animals and minerals. TCM has been practiced in China for more than 2000 years, and for the past 200 years has been used in treatment of drug addiction. Ten Chinese medicines for the treatment of opiate addiction have been approved by the Chinese State Food and Drug Administration (SFDA), and at least 6 are in clinical trials. The general therapeutic principle of Chinese medicine developed was based on its unique theory of "reinforcing healthy Qi and resolving and removing effects of toxicity". Acupuncture, another essential part of TCM, which was developed based on the principle that "functions of the human body are controlled by the 'Jing-Luo' and 'Qi-Xue' system", has been used not only in China, but also in Europe, the USA and other countries, for controlling opiate addiction. There are some advantages in using TCM for opiate detoxification, including less harmful side effects, high safety and ideal effects in the inhibition of protracted withdrawal symptoms and relapse. Co-administration of TCM with modern medicine shows some synergistic effects in detoxification. Many TCM for detoxification also have efficacy in the rehabilitation of abnormal body functions induced by chronic drug use, including improving immune function, increasing working memory and preventing neurological disorder. Given that TCM is effective in the prevention of relapse and causes fewer side effects, it may be used widely in the treatment of opiate addiction.

  9. Developing a library of authenticated Traditional Chinese Medicinal (TCM) plants for systematic biological evaluation — Rationale, methods and preliminary results from a Sino-American collaboration☆

    Science.gov (United States)

    Eisenberg, David M.; Harris, Eric S.J.; Littlefield, Bruce A.; Cao, Shugeng; Craycroft, Jane A.; Scholten, Robert; Bayliss, Peter; Fu, Yanling; Wang, Wenquan; Qiao, Yanjiang; Zhao, Zhongzhen; Chen, Hubiao; Liu, Yong; Kaptchuk, Ted; Hahn, William C.; Wang, Xiaoxing; Roberts, Thomas; Shamu, Caroline E.; Clardy, Jon

    2011-01-01

    While the popularity of and expenditures for herbal therapies (aka “ethnomedicines”) have increased globally in recent years, their efficacy, safety, mechanisms of action, potential as novel therapeutic agents, cost-effectiveness, or lack thereof, remain poorly defined and controversial. Moreover, published clinical trials evaluating the efficacy of herbal therapies have rightfully been criticized, post hoc, for their lack of quality assurance and reproducibility of study materials, as well as a lack of demonstration of plausible mechanisms and dosing effects. In short, clinical botanical investigations have suffered from the lack of a cohesive research strategy which draws on the expertise of all relevant specialties. With this as background, US and Chinese co-investigators with expertise in Traditional Chinese Medicine (TCM), botany, chemistry and drug discovery, have jointly established a prototype library consisting of 202 authenticated medicinal plant and fungal species that collectively represent the therapeutic content of the majority of all commonly prescribed TCM herbal prescriptions. Currently housed at Harvard University, the library consists of duplicate or triplicate kilogram quantities of each authenticated and processed species, as well as “detanninized” extracts and sub-fractions of each mother extract. Each species has been collected at 2–3 sites, each separated geographically by hundreds of miles, with precise GPS documentation, and authenticated visually and chemically prior to testing for heavy metals and/or pesticides contamination. An explicit decision process has been developed whereby samples with the least contamination were selected to undergo ethanol extraction and HPLC sub-fractionation in preparation for high throughput screening across a broad array of biological targets including cancer biology targets. As envisioned, the subfractions in this artisan collection of authenticated medicinal plants will be tested for biological

  10. Resources of medicinal plants in China

    OpenAIRE

    Guan-Fu He

    1991-01-01

    Four aspect dealts with in this paper are as follows: 1. environment of medicinal plants; 2. brief history on studies of medicinal plants; 3. species of medicinal plants; 4. studies on development and utilization of medicinal plant resources.

  11. Role of Traditional Chinese Medicine in Integrative Medicine

    Institute of Scientific and Technical Information of China (English)

    吕爱平; 吕维柏; 吕青平

    2004-01-01

    @@ Complementary & alternative medicine (CAM) is getting more and more important in improving human health. Traditional Chinese medicine (TCM), with her thousands of years history and contributions to the health of Chinese people, definitely is vital in CAM in China. Medical sciences including CAM and mainstream medicine, with unified specific aim, could be integrated and become integrative medicine. During the integration, TCM would contribute much more in the progress with her cultural background and clinical efficacy. This paper will discuss how TCM takes part in the inte gration via her function in clinical practice.

  12. MEDICINAL PLANTS AGAINST LIVER DISEASES

    OpenAIRE

    Pandey Govind

    2011-01-01

    India is the largest producer of medicinal plants and is rightly called the “Botanical Garden of the World”. The medicinal plants have very important place in the health and vitality of human beings as well as animals. As per the WHO estimates, about three quarters of the world’s population currently use herbs and other traditional medicines to cure various diseases, including liver disorders. Hence, several phytomedicines (medicinal plants or herbal drugs) are now used for the prevention and...

  13. Artemisinin, a miracle of traditional Chinese medicine.

    Science.gov (United States)

    Kong, Ling Yi; Tan, Ren Xiang

    2015-12-19

    The 2015 Nobel Prize in Physiology or Medicine, shared by Professor Youyou Tu, focused worldwide attention on artemisinin, a natural product antimalarial drug inspired by traditional Chinese medicine (TCM). This is the first Nobel Prize in natural sciences presented to a Chinese scientist for her impactful research work in China in collaboration with other Chinese scientists. We are delighted to provide the background and implications of the discovery of artemisinin, along with our personal viewpoints toward the affordability of modern medicines from natural products. PMID:26561737

  14. DNA based identification of medicinal materials in Chinese patent medicines

    OpenAIRE

    Rong Chen; Juan Dong; Xin Cui; Wei Wang; Afshan Yasmeen; Yun Deng; Xiaomao Zeng; Zhuo Tang

    2012-01-01

    Chinese patent medicines (CPM) are highly processed and easy to use Traditional Chinese Medicine (TCM). The market for CPM in China alone is tens of billions US dollars annually and some of the CPM are also used as dietary supplements for health augmentation in the western countries. But concerns continue to be raised about the legality, safety and efficacy of many popular CPM. Here we report a pioneer work of applying molecular biotechnology to the identification of CPM, particularly well re...

  15. Shanghai University of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The 2006 reception conference of the International Education College of the Shanghai University of Traditional Chinese Medicine was held April 28 in Beijing, unveiling its overseas students recruitment program this year.

  16. Chinese Medicine: A Cognitive and Epistemological Review

    OpenAIRE

    Ben Kavoussi

    2007-01-01

    In spite of the common belief that Chinese natural philosophy and medicine have a unique frame of reference completely foreign to the West, this article argues that they in fact have significant cognitive and epistemic similarities with certain esoteric health beliefs of pre-Christian Europe. From the standpoint of Cognitive Science, Chinese Medicine appears as a proto-scientific system of health observances and practices based on a symptomological classification of disease using two elementa...

  17. Chinese medicinal herbs for chronic hepatitis B

    DEFF Research Database (Denmark)

    Liu, J P; McIntosh, H; Lin, Haili

    2001-01-01

    Hepatitis B virus infection is a serious health problem worldwide. Traditional Chinese medicinal herbs have been widely used to treat chronic liver diseases, and many controlled trials have been done to investigate their efficacy.......Hepatitis B virus infection is a serious health problem worldwide. Traditional Chinese medicinal herbs have been widely used to treat chronic liver diseases, and many controlled trials have been done to investigate their efficacy....

  18. From the traditional Chinese medicine plant Schisandra chinensis new scaffolds effective on HIV-1 reverse transcriptase resistant to non-nucleoside inhibitors.

    Science.gov (United States)

    Xu, Lijia; Grandi, Nicole; Del Vecchio, Claudia; Mandas, Daniela; Corona, Angela; Piano, Dario; Esposito, Francesca; Parolin, Cristina; Tramontano, Enzo

    2015-04-01

    HIV-1 reverse transcriptase (RT) is still an extremely attractive pharmaceutical target for the identification of new inhibitors possibly active on drug resistant strains. Medicinal plants are a rich source of chemical diversity and can be used to identify novel scaffolds to be further developed by chemical modifications. We investigated the ability of the main lignans from Schisandra chinensis (Turcz.) Baill. fruits, commonly used in Traditional Chinese Medicine, to affect HIV-1 RT functions. We purified 6 lignans from Schisandra chinensis fruits and assayed their effects on HIV-1 RT and viral replication. Among the S. chinensis fruit lignans, Schisandrin B and Deoxyschizandrin selectively inhibited the HIV-1 RT-associated DNA polymerase activity. Structure activity relationship revealed the importance of cyclooctadiene ring substituents for efficacy. In addition, Schisandrin B was also able to impair HIV-1 RT drug resistant mutants and the early phases of viral replication. We identified Schisandrin B and Deoxyschizandrin as new scaffold for the further development of novel HIV-1 RT inhibitors.

  19. Review of a new book——Chemical Components of Source Plants in Traditional Chinese Medicine(中药原植物化学成分集)%《中药原植物化学成分集》简介

    Institute of Scientific and Technical Information of China (English)

    翁维良

    2009-01-01

    @@ The book Chemical Components of Source Plants in Traditional Chinese Medicine (three-volumes, compiled by Jia-Ju Zhou, et al., scientists of the Chinese Academy of Sciences, and published by the Science Press, Beijing, 2009) is a large-scale handbook derived from the authors' long-term studies on chemical and pharmacological characteristics of traditional Chinese medicine (TCM). This book of 9.6 million words includes 23 033 chemical components isolated from 6700 medicinal plants, collected from 5507 articles published before 2005 in both Chinese and international journals. It introduces and integrates a great number of recently worldwide research accomplishments into the information system of TCM.

  20. Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal plants.

    Science.gov (United States)

    Zhang, Yaofang; Yu, Bo; Sui, Yujie; Gao, Xin; Yang, Hong; Ma, Tonghui

    2014-01-01

    Inhibitors of cystic fibrosis transmembrane conductance regulator (CFTR) have been widely used for characterizing CFTR function in epithelial fluid transport and in diseases such as secretory diarrhea, polycystic kidney disease and cystic fibrosis. Few small molecule CFTR inhibitors have been discovered so far from combinatorial compound library. In the present study, we used a high throughput screening (HTS)-based natural product discovery strategy to identify new CFTR inhibitors from Chinese medicinal herbs. By screening 40,000 small molecule fractions from 500 herbal plants, we identified 42 positive fractions from 5 herbs and isolated two compounds that inhibited CFTR conductance from Chinese wild grapevine (Vitis amurensis Rupr). Mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies determined the two active compounds as trans-ε-viniferin (TV) and r-2-viniferin (RV), respectively. Both compounds dose-dependently blocked CFTR-mediated iodide influx with IC50 around 20 μM. Further analysis by excised inside-out patch-clamp indicated strong inhibition of protein kinase A (PKA)-activated CFTR chloride currents by TV and RV. In ex vivo studies, TV and RV inhibited CFTR-mediated short-circuit Cl- currents in isolated rat colonic mucosa in a dose-dependent manner. In a closed-loop mouse model, intraluminal applications of TV (2.5 μg) and RV (4.5 μg) significantly reduced cholera toxin-induced intestinal fluid secretion. The present study identified two resveratrol oligomers as new CFTR inhibitors and validates our high-throughput screening method for discovery of bioactive compounds from natural products with complex chemical ingredients such as herbal plants.

  1. Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal plants.

    Directory of Open Access Journals (Sweden)

    Yaofang Zhang

    Full Text Available Inhibitors of cystic fibrosis transmembrane conductance regulator (CFTR have been widely used for characterizing CFTR function in epithelial fluid transport and in diseases such as secretory diarrhea, polycystic kidney disease and cystic fibrosis. Few small molecule CFTR inhibitors have been discovered so far from combinatorial compound library. In the present study, we used a high throughput screening (HTS-based natural product discovery strategy to identify new CFTR inhibitors from Chinese medicinal herbs. By screening 40,000 small molecule fractions from 500 herbal plants, we identified 42 positive fractions from 5 herbs and isolated two compounds that inhibited CFTR conductance from Chinese wild grapevine (Vitis amurensis Rupr. Mass spectrometry (MS and nuclear magnetic resonance (NMR studies determined the two active compounds as trans-ε-viniferin (TV and r-2-viniferin (RV, respectively. Both compounds dose-dependently blocked CFTR-mediated iodide influx with IC50 around 20 μM. Further analysis by excised inside-out patch-clamp indicated strong inhibition of protein kinase A (PKA-activated CFTR chloride currents by TV and RV. In ex vivo studies, TV and RV inhibited CFTR-mediated short-circuit Cl- currents in isolated rat colonic mucosa in a dose-dependent manner. In a closed-loop mouse model, intraluminal applications of TV (2.5 μg and RV (4.5 μg significantly reduced cholera toxin-induced intestinal fluid secretion. The present study identified two resveratrol oligomers as new CFTR inhibitors and validates our high-throughput screening method for discovery of bioactive compounds from natural products with complex chemical ingredients such as herbal plants.

  2. Identification of resveratrol oligomers as inhibitors of cystic fibrosis transmembrane conductance regulator by high-throughput screening of natural products from chinese medicinal plants.

    Science.gov (United States)

    Zhang, Yaofang; Yu, Bo; Sui, Yujie; Gao, Xin; Yang, Hong; Ma, Tonghui

    2014-01-01

    Inhibitors of cystic fibrosis transmembrane conductance regulator (CFTR) have been widely used for characterizing CFTR function in epithelial fluid transport and in diseases such as secretory diarrhea, polycystic kidney disease and cystic fibrosis. Few small molecule CFTR inhibitors have been discovered so far from combinatorial compound library. In the present study, we used a high throughput screening (HTS)-based natural product discovery strategy to identify new CFTR inhibitors from Chinese medicinal herbs. By screening 40,000 small molecule fractions from 500 herbal plants, we identified 42 positive fractions from 5 herbs and isolated two compounds that inhibited CFTR conductance from Chinese wild grapevine (Vitis amurensis Rupr). Mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies determined the two active compounds as trans-ε-viniferin (TV) and r-2-viniferin (RV), respectively. Both compounds dose-dependently blocked CFTR-mediated iodide influx with IC50 around 20 μM. Further analysis by excised inside-out patch-clamp indicated strong inhibition of protein kinase A (PKA)-activated CFTR chloride currents by TV and RV. In ex vivo studies, TV and RV inhibited CFTR-mediated short-circuit Cl- currents in isolated rat colonic mucosa in a dose-dependent manner. In a closed-loop mouse model, intraluminal applications of TV (2.5 μg) and RV (4.5 μg) significantly reduced cholera toxin-induced intestinal fluid secretion. The present study identified two resveratrol oligomers as new CFTR inhibitors and validates our high-throughput screening method for discovery of bioactive compounds from natural products with complex chemical ingredients such as herbal plants. PMID:24714160

  3. [Interaction between medicines and medicinal plants].

    Science.gov (United States)

    Tres, J C

    2006-01-01

    In recent years there has been a notable increase in the consumption of medicinal plants in Spanish society. This might be due to the fact that in some cases they have shown themselves to be efficient in treating certain pathologies and to the erroneous perception that these products are innocuous. Medicinal plants behave as authentic medicines since the chemical substances of which they are formed can have a biological activity in humans. For this reason, their joint administration with "conventional medicines" can produce variations in the magnitude of the effect. This type of interaction, just like those produced between two or more medicines, can produce pharmacokinetic mechanisms if they affect the processes of absorption, distribution, metabolism and excretion, or pharmacodynamic mechanisms if they affect the result of the pharmacological action. In the medical literature there are few articles and notifications of cases concerning the adverse effects and interactions that affect medicinal plants, which probably reflects an under-notification of these phenomena. If we add to this the lack of experimental data and controlled studies, perception of their prevalence is difficult or nearly impossible. This article sets out, in an order that will be explained later, the findings of an exhaustive review of the medical literature with the aim of making its existence known to the reader, without going into other considerations, such as the degree of evidence for example, which will be the subject of forthcoming articles.

  4. Antioxidant Potential of Different Medicinal Plants

    OpenAIRE

    Vasanthi P; Parameswari CS

    2015-01-01

    Medicinal plants are the resource of new drug. Most of the modern medicines are produced indirectly from medicinal plants. Plants are directly used as medicines by a majority of cultures around the world. Studying medicinal plants helps to understand plant toxicity and protect human and animals from natural poisons. Medicinal plants are the important sources for pharmaceutical manufacturing. In developing countries, herbal medicines are considered to be readily available, accessible, affordab...

  5. The Transmission of Chinese Medicine in Australia

    Directory of Open Access Journals (Sweden)

    Mary Garvey

    2011-12-01

    Full Text Available The paper explores some of the issues concerning the transmission of Chinese medicine in Australia, its practitioner training and the future of Chinese medicine as a distinct medical discipline in the Australian context. In China over the last century Chinese medicine was overhauled in order to align it with the biomedical perspective prevalent in the West. These changes, in turn, had important consequences for the transmission of CM in Australia and the West. But while the biomedicalisation of CM has offered the path of least resistance, it has also lead to unworkable simplifications and methodological failures. The paper thus argues for a renewed access to the tradition’s primary sources in order to ally the distinctive features and methods of traditional practice with biomedicine, as an alternative to an outright integration into biomedical practice.

  6. Chinese herbal medicine research in eczema treatment

    Directory of Open Access Journals (Sweden)

    Leung Ping

    2011-04-01

    Full Text Available Abstract Eczema is a chronic relapsing atopic dermatitis (AD associated with pruritus, sleep disturbance and poor quality of life of the patient. Treatment of eczema includes use of emollient, topical and systemic antimicrobial agents, corticosteroid or immunomodulating agents. Many patients also seek alternative treatments such as dietary avoidance, supplementation or both. This article reviews the basic pathophysiology of eczema and clinical trials involving Chinese medicine in the treatment of eczema. Research reports on Chinese herbal medicine for eczema were retrieved from PubMed and the Cochrane Database for Systematic Reviews for this review. Only a few RCTs demonstrated the efficacy (or lack of efficacy of Chinese medicinal herbs in treating atopic eczema. Further larger scale trials are warranted.

  7. Comparison of Sasang Constitutional Medicine, Traditional Chinese Medicine and Ayurveda

    Directory of Open Access Journals (Sweden)

    Jong Yeol Kim

    2011-01-01

    Full Text Available Sasang constitutional medicine (SCM, traditional Chinese medicine (TCM and Ayurveda are three different forms of Asian traditional medicine. Although these traditions share a lot in common as holistic medicines, the different philosophical foundations found in each confer distinguishing attributes and unique qualities. SCM is based on a constitution-based approach, and is in this way relatively more similar to the Ayurvedic tradition than to the TCM, although many of the basic SCM theories were originally derived from TCM, a syndrome-based medicine. SCM and TCM use the same botanical materials that are distributed mainly in the East Asian region, but the basic principles of usage and the underlying rationale are completely different from each other. Meanwhile, the principles of the Ayurvedic use of botanical resources are very similar to those seen in SCM, but the medicinal herbs used in Ayurveda generally originate from the West Asian region which displays a different spectrum of flora.

  8. MEDICINAL PLANTS OF RAJASTHAN IN INDIAN SYSTEM OF MEDICINE

    OpenAIRE

    Tripathi, Y.C.; Prabhu, V V; R S Pal; R N Mishra

    1996-01-01

    Medicinal plants used in Indian system of medicine from Rajasthan state have been surveyed and catagorised systematically. The paper deals with 205 medicinal plants, thoroughly indexed along with their important traditional application for the cure of various ailments.

  9. Chinese herbal medicine for treatment of dislipidemia

    Institute of Scientific and Technical Information of China (English)

    Haiyun Wu; Jianwei Bei; Jiao Guo

    2009-01-01

    Prevalence of dislipidemia is increasing rapidly in China and there has been a growing interest in Chinese herbal medicine for the treatment of hyperlipidemia both inside and outside China. In this article, lipids regulating effects of 9 herbs or their extracts and 5 herbal formulae which have been published in English-language literature are reviewed. Although evidence from animals and humans consistently supports the therapeutic activities of these Chinese herbal medicines, few multi-center large-scale clinical trials have been conducted to confirm the efficacy and evaluate their safety.

  10. [Scientific Positioning of Traditional Chinese Medicine].

    Science.gov (United States)

    Li, Yong-ming

    2016-03-01

    Whether traditional Chinese medicine (TCM) could be categorized as a kind of science or not has been a controversial issue over last century. Part of the confusion is caused by the indistinguishable usage of Chinese words "science" and "scientific" during discussion. According to western academic standards, TCM cannot be considered as pure or conventional science. However, in author's view, the foundation of a majority part of TCM practice is probably scientific, while many TCM theories remain unproved. In this article, medical theories and practices are classified based on scientific content into eight levels: medical science, scientific medicine, medical system, medical theory, medical opinion, medical belief, medical cultism, and medical fraud. Both Western medicine and TCM are positioned in this system accordingly. Currently, the scientific level of TCM is much lower than that of Western medicine, and more research is needed for its improvement.

  11. [Chinese Medicine in Overall Modern Scientific Technologies].

    Science.gov (United States)

    Tan, Yuan-sheng; Zeng Yong

    2015-10-01

    Chinese medicine (CM) develops with the survival, reproduction, growth, and progressing of the Chinese nation. Scientific technologies not only promote continual progressing of human societies, but also provide new ideas and methods for the development of CM. In recent years, great changes have taken place in CM complying with developing modern scientific technologies, mainly manifested in the depth of CM theories at molecular levels, the combination of syndrome differentiation and disease identification, continuous innovation and development of clinical diagnosis and treatment techniques, diversified dosages of Chinese materia medica, the academic tendency of education patterns, occupational refinement, diversified medical practice modes, and so on. PMID:26677664

  12. A R2R3-MYB Transcription Factor Regulates the Flavonol Biosynthetic Pathway in a Traditional Chinese Medicinal Plant, Epimedium sagittatum

    Science.gov (United States)

    Huang, Wenjun; Khaldun, A. B. M.; Chen, Jianjun; Zhang, Chanjuan; Lv, Haiyan; Yuan, Ling; Wang, Ying

    2016-01-01

    Flavonols as plant secondary metabolites with vital roles in plant development and defense against UV light, have been demonstrated to be the main bioactive components (BCs) in the genus Epimedium plants, several species of which are used as materials for Herba Epimedii, an important traditional Chinese medicine. The flavonol biosynthetic pathway genes had been already isolated from Epimedium sagittatum, but a R2R3-MYB transcription factor regulating the flavonol synthesis has not been functionally characterized so far in Epimedium plants. In this study, we isolated and characterized the R2R3-MYB transcription factor EsMYBF1 involved in regulation of the flavonol biosynthetic pathway from E. sagittatum. Sequence analysis indicated that EsMYBF1 belongs to the subgroup 7 of R2R3-MYB family which contains the flavonol-specific MYB regulators identified to date. Transient reporter assay showed that EsMYBF1 strongly activated the promoters of EsF3H (flavanone 3-hydroxylase) and EsFLS (flavonol synthase), but not the promoters of EsDFRs (dihydroflavonol 4-reductase) and EsANS (anthocyanidin synthase) in transiently transformed Nicotiana benthamiana leaves. Both yeast two-hybrid assay and transient reporter assay validated EsMYBF1 to be independent of EsTT8, or AtTT8 bHLH regulators of the flavonoid pathway as cofactors. Ectopic expression of EsMYBF1 in transgenic tobacco resulted in the increased flavonol content and the decreased anthocyanin content in flowers. Correspondingly, the structural genes involved in flavonol synthesis were upregulated in the EsMYBF1 overexpression lines, including NtCHS (chalcone synthase), NtCHI (chalcone isomerase), NtF3H and NtFLS, whereas the late biosynthetic genes of the anthocyanin pathway (NtDFR and NtANS) were remarkably downregulated, compared to the controls. These results suggest that EsMYBF1 is a flavonol-specific R2R3-MYB regulator, and involved in regulation of the biosynthesis of the flavonol-derived BCs in E. sagittatum. Thus

  13. A R2R3-MYB Transcription Factor Regulates the Flavonol Biosynthetic Pathway in a Traditional Chinese Medicinal Plant, Epimedium sagittatum.

    Science.gov (United States)

    Huang, Wenjun; Khaldun, A B M; Chen, Jianjun; Zhang, Chanjuan; Lv, Haiyan; Yuan, Ling; Wang, Ying

    2016-01-01

    Flavonols as plant secondary metabolites with vital roles in plant development and defense against UV light, have been demonstrated to be the main bioactive components (BCs) in the genus Epimedium plants, several species of which are used as materials for Herba Epimedii, an important traditional Chinese medicine. The flavonol biosynthetic pathway genes had been already isolated from Epimedium sagittatum, but a R2R3-MYB transcription factor regulating the flavonol synthesis has not been functionally characterized so far in Epimedium plants. In this study, we isolated and characterized the R2R3-MYB transcription factor EsMYBF1 involved in regulation of the flavonol biosynthetic pathway from E. sagittatum. Sequence analysis indicated that EsMYBF1 belongs to the subgroup 7 of R2R3-MYB family which contains the flavonol-specific MYB regulators identified to date. Transient reporter assay showed that EsMYBF1 strongly activated the promoters of EsF3H (flavanone 3-hydroxylase) and EsFLS (flavonol synthase), but not the promoters of EsDFRs (dihydroflavonol 4-reductase) and EsANS (anthocyanidin synthase) in transiently transformed Nicotiana benthamiana leaves. Both yeast two-hybrid assay and transient reporter assay validated EsMYBF1 to be independent of EsTT8, or AtTT8 bHLH regulators of the flavonoid pathway as cofactors. Ectopic expression of EsMYBF1 in transgenic tobacco resulted in the increased flavonol content and the decreased anthocyanin content in flowers. Correspondingly, the structural genes involved in flavonol synthesis were upregulated in the EsMYBF1 overexpression lines, including NtCHS (chalcone synthase), NtCHI (chalcone isomerase), NtF3H and NtFLS, whereas the late biosynthetic genes of the anthocyanin pathway (NtDFR and NtANS) were remarkably downregulated, compared to the controls. These results suggest that EsMYBF1 is a flavonol-specific R2R3-MYB regulator, and involved in regulation of the biosynthesis of the flavonol-derived BCs in E. sagittatum. Thus

  14. A R2R3-MYB transcription factor regulates the flavonol biosynthetic pathway in a traditional Chinese medicinal plant, Epimedium sagittatum

    Directory of Open Access Journals (Sweden)

    Wenjun Huang

    2016-07-01

    Full Text Available Flavonols as plant secondary metabolites with vital roles in plant development and defense against UV light, have been demonstrated to be the main bioactive components in the genus Epimedium plants, several species of which are used as materials for Herba Epimedii, an important traditional Chinese medicine. The flavonol biosynthetic pathway genes had been already isolated from E. sagittatum, but a R2R3-MYB transcription factor regulating the flavonol synthesis has not been functionally characterized so far in Epimedium plants. In this study, we isolated and characterized the R2R3-MYB transcription factor EsMYBF1 involved in regulation of the flavonol biosynthetic pathway from E. sagittatum. Sequence analysis indicated that EsMYBF1 belongs to the subgroup 7 of R2R3-MYB family which contains the flavonol-specific MYB regulators identified to date. Transient reporter assay showed that EsMYBF1 strongly activated the promoters of EsF3H (flavanone 3-hydroxylase and EsFLS (flavonol synthase, but not the promoters of EsDFRs (dihydroflavonol 4-reductase and EsANS (anthocyanidin synthase in transiently transformed Nicotiana benthamiana leaves. Both yeast two-hybrid assay and transient reporter assay validated EsMYBF1 to be independent of EsTT8, or AtTT8 bHLH regulators of the flavonoid pathway as cofactors. Ectopic expression of EsMYBF1 in transgenic tobacco resulted in the increased flavonol content and the decreased anthocyanin content in flowers. Correspondingly, the structural genes involved in flavonol synthesis were upregulated in the EsMYBF1 overexpression lines, including NtCHS (chalcone synthase, NtCHI (chalcone isomerase, NtF3H and NtFLS, whereas the late biosynthetic genes of the anthocyanin pathway (NtDFR and NtANS were remarkably downregulated, compared to the controls. These results suggest that EsMYBF1 is a flavonol-specific R2R3-MYB regulator, and involved in regulation of the biosynthesis of the flavonol-derived bioactive components in E

  15. DNA based identification of medicinal materials in Chinese patent medicines

    Science.gov (United States)

    Chen, Rong; Dong, Juan; Cui, Xin; Wang, Wei; Yasmeen, Afshan; Deng, Yun; Zeng, Xiaomao; Tang, Zhuo

    2012-12-01

    Chinese patent medicines (CPM) are highly processed and easy to use Traditional Chinese Medicine (TCM). The market for CPM in China alone is tens of billions US dollars annually and some of the CPM are also used as dietary supplements for health augmentation in the western countries. But concerns continue to be raised about the legality, safety and efficacy of many popular CPM. Here we report a pioneer work of applying molecular biotechnology to the identification of CPM, particularly well refined oral liquids and injections. What's more, this PCR based method can also be developed to an easy to use and cost-effective visual chip by taking advantage of G-quadruplex based Hybridization Chain Reaction. This study demonstrates that DNA identification of specific Medicinal materials is an efficient and cost-effective way to audit highly processed CPM and will assist in monitoring their quality and legality.

  16. MEDICINAL PLANTS AGAINST LIVER DISEASES

    Directory of Open Access Journals (Sweden)

    Pandey Govind

    2011-05-01

    Full Text Available India is the largest producer of medicinal plants and is rightly called the “Botanical Garden of the World”. The medicinal plants have very important place in the health and vitality of human beings as well as animals. As per the WHO estimates, about three quarters of the world’s population currently use herbs and other traditional medicines to cure various diseases, including liver disorders. Hence, several phytomedicines (medicinal plants or herbal drugs are now used for the prevention and treatment of various liver disorders. Although experimental studies have been conducted on a number of these plants and their formulations, however, only some plants have clearly shown the hepatogenic / hepatoprotective effects against liver diseases or hepatotoxicity caused by variety of hepatotoxic agents such as chemicals, drugs, pollutants, and infections from parasites, bacteria or viruses (e.g., hepatitis A, B and C, etc. Indeed, to obtain satisfactory herbal drugs for treating severe liver diseases, the medicinal plants must be evaluated systematically for properties like antiviral activity (Hepatitis B, Hepatitis C, etc., antihepatotoxicity activity (antioxidants and others, stimulation of liver regeneration and choleretic activity. A combination of different herbal extracts / fractions is likely to provide desired activities to cure severe liver diseases. The medicinal plants contain several phytochemicals which possess strong antioxidant property, leading to antihepatotoxic activity.

  17. Latest Progress on Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    Tianjin Press of Chinese Herbal Medicines

    2010-01-01

    @@ Chinese Herbal Medicines (CHM) has been recently included in the Wanfang Database-Digital Periodical Group, China Academic Journals Integrated Online Database, Index of Copernicus (IC) in Poland, Chemical Abstracts Service (CAS) in USA, and Ulrich's Periodicals Directory domestically and abroad.

  18. Plants and Medicinal Chemistry--2

    Science.gov (United States)

    Bailey, D.

    1977-01-01

    Second of a two part article on the influence of plants on medicinal chemistry. This part considers how drugs work, the attempts to develop anaesthetics safer than cocaine, and useful poisons. (Author/SL)

  19. Introducing Considerations in the Translation of Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Sonya E.Pritzker; Ka-Kit Hui

    2014-01-01

    This article introduces the document,Considerations in the Translation of Chinese Medicine, published in PDF form online in both Chinese and English. This 20-page document includes several sections describing why theConsiderations is necessary, the speciifcity of texts in Chinese medicine; the history of translation in Chinese medicine; who constitutes an ideal translator of Chinese medicine; what types of language exist in Chinese medicine; and speciifc issues in the translation of Chinese medicine, such as domestication versus foreignization, technical terminology, period-speciifc language, style, polysemy, and etymological translation. The final section offers a brief advisory for consumers, and concludes with a call to further discussion, and action, specifically in the development of international collaborative efforts towards the creation of more rigorous guidelines for the translation of Chinese medicine. The current article provides an overview of several of these sections, and includes links to the original document.

  20. Antifertility activity of medicinal plants.

    Science.gov (United States)

    Daniyal, Muhammad; Akram, Muhammad

    2015-07-01

    The aim of this review was to provide a comprehensive summary of medicinal plants used as antifertility agents in females throughout the world by various tribes and ethnic groups. We undertook an extensive bibliographic review by analyzing classical text books and peer reviewed papers, and further consulting well accepted worldwide scientific databases. We performed CENTRAL, Embase, and PubMed searches using terms such as "antifertility", "anti-implantation", "antiovulation", and "antispermatogenic" activity of plants. Plants, including their parts and extracts, that have traditionally been used to facilitate antifertility have been considered as antifertility agents. In this paper, various medicinal plants have been reviewed for thorough studies such as Polygonum hydropiper Linn, Citrus limonum, Piper nigrum Linn, Juniperis communis, Achyanthes aspera, Azadirachta indica, Tinospora cordifolia, and Barleria prionitis. Many of these medicinal plants appear to act through an antizygotic mechanism. This review clearly demonstrates that it is time to expand upon experimental studies to source new potential chemical constituents from medicinal plants; plant extracts and their active constituents should be further investigated for their mechanisms. This review creates a solid foundation upon which to further study the efficacy of plants that are both currently used by women as traditional antifertility medicines, but also could be efficacious as an antifertility agent with additional research and study.

  1. Antifertility activity of medicinal plants.

    Science.gov (United States)

    Daniyal, Muhammad; Akram, Muhammad

    2015-07-01

    The aim of this review was to provide a comprehensive summary of medicinal plants used as antifertility agents in females throughout the world by various tribes and ethnic groups. We undertook an extensive bibliographic review by analyzing classical text books and peer reviewed papers, and further consulting well accepted worldwide scientific databases. We performed CENTRAL, Embase, and PubMed searches using terms such as "antifertility", "anti-implantation", "antiovulation", and "antispermatogenic" activity of plants. Plants, including their parts and extracts, that have traditionally been used to facilitate antifertility have been considered as antifertility agents. In this paper, various medicinal plants have been reviewed for thorough studies such as Polygonum hydropiper Linn, Citrus limonum, Piper nigrum Linn, Juniperis communis, Achyanthes aspera, Azadirachta indica, Tinospora cordifolia, and Barleria prionitis. Many of these medicinal plants appear to act through an antizygotic mechanism. This review clearly demonstrates that it is time to expand upon experimental studies to source new potential chemical constituents from medicinal plants; plant extracts and their active constituents should be further investigated for their mechanisms. This review creates a solid foundation upon which to further study the efficacy of plants that are both currently used by women as traditional antifertility medicines, but also could be efficacious as an antifertility agent with additional research and study. PMID:25921562

  2. National semantic infrastructure for traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    Hua-jun CHEN

    2012-01-01

    1 Introduction Traditional Chinese medicine (TCM) is "the traditional medicine that originated in China,and is characterized by holism and treatment based on pattern identification/syndrome differentiation" (WHO,2007).In China,traditional medicine accounts for around 40% of all healthcare delivered;in the West,TCM is increasingly adopted by medical practitioners as a form of complementary and altemative medicine (CAM) (WHO,2002).Both in China and in the West,scientists are attempting to bring the ancient heritage of TCM into line with modem standards,through the scientific development of TCM in the direction of evidence-based medicine (Qiu,2007).There is a pressing need for the digital preservation and global access of TCM knowledge assets.

  3. Safety concerns of herbal products and traditional Chinese herbal medicines: Dehydropyrrolizidine alkaloids and aristolochic acid

    Science.gov (United States)

    In many countries, including the United States, herbal supplements, tisanes and vegetable products, including traditional Chinese medicines, are largely unregulated and their content is not registered, monitored or verified. Consequently, potent plant toxins including dehydropyrrolizidine alkaloids ...

  4. Study on international standard multilingual nomenclature of Chinese medicine.

    Science.gov (United States)

    Wang, Kui; Liu, Lu; Li, Wei; Shi, Da-zhuo; Zeng, Wen-ying; Zhu, Mian-sheng; Angles, Michel; Attali, Jean-Raymond; Choy, Pedro; Choy, Joao; Wu, Chi-haur; Zhai, Fu-han; Ramon, Maria Calduch; Chung, Ching

    2010-04-01

    The International Standard Chinese-English Basic Nomenclature of Chinese medicine (ISN) was released in 2007, a nomenclature list consisting of 6 500 Chinese medical terms. ISN was the culmination of several years of collaborative diligent work of over 200 specialists who represent Chinese medicine in 68 countries. The overall goal for devising standard English nomenclature for Chinese medicine is to develop a practical international standard nomenclature for Chinese medical basic terms, to make it compatible with contemporary research and educational standards in the globalized health care service. In this article, provided is an overview of principles and methods for the multilingual translations, the processes behind the particular content of the Chinese-English ISN and an introduction to the ongoing new projects, i.e. the multilingual versions of ISN (International Standards of Chinese-Spanish, Chinese-French and Chinese-Portuguese Basic Nomenclature of Chinese Medicine).

  5. [Study on determination of Chinese medicine flavor and its regularity].

    Science.gov (United States)

    Zhang, Zhuo; Zhang, Wei

    2014-02-01

    Five flavors are basic nature of Chinese medicine. But the labeling of Chinese medicine flavors was in a chaos. Song Jin and Yuan dynasty is a transconformation stage of labeling Chinese medicine flavors. In this article the author put forward that the determination of Chinese medicine flavor shifted from tasting of early and middle age of Northern Song dynasty to categorical analogizing and functional analogizing in the late age of Northern Song dynasty. The latter method had a flourished development in Southern Song, Jin and Yuan dynasty. This regularity conclusion has provided a reference for the standardizing Chinese medicine flavors. PMID:24946566

  6. Sasang Constitutional Medicine and Traditional Chinese Medicine: A Comparative Overview

    Directory of Open Access Journals (Sweden)

    Junghee Yoo

    2012-01-01

    Full Text Available Sasang constitutional medicine (SCM is a holistic typological constitution medicine which balances psychological, social, and physical aspects of an individual to achieve wellness and increase longevity. SCM has the qualities of preventative medicine, as it emphasizes daily health management based on constitutionally differentiated regimens and self-cultivation of the mind and body. This review's goal is to establish a fundamental understanding of SCM and to provide a foundation for further study. It compares the similarities and differences of philosophical origins, perspectives on the mind (heart, typological systems, pathology, and therapeutics between SCM and traditional Chinese medicine (TCM. TCM is based on the Taoist view of the universe and humanity. The health and longevity of an individual depends on a harmonious relationship with the universe. On the other hand, SCM is based on the Confucian view of the universe and humanity. SCM focuses on the influence of human affairs on the psyche, physiology, and pathology.

  7. [Inheritance and innovation of traditional Chinese medicinal authentication].

    Science.gov (United States)

    Zhao, Zhong-zhen; Chen, Hu-biao; Xiao, Pei-gen; Guo, Ping; Liang, Zhi-tao; Hung, Fanny; Wong, Lai-lai; Brand, Eric; Liu, Jing

    2015-09-01

    Chinese medicinal authentication is fundamental for the standardization and globalization of Chinese medicine. The discipline of authentication addresses difficult issues that have remained unresolved for thousands of years, and is essential for preserving safety. Chinese medicinal authentication has both scientific and traditional cultural connotations; the use of scientific methods to elucidate traditional experience-based differentiation carries the legacy of Chinese medicine forward, and offers immediate practical significance and long-term scientific value. In this paper, a path of inheritance and innovation is explored through the scientific exposition of Chinese medicinal authentication, featuring a review of specialized publications, the establishment of a Chinese medicine specimen center and Chinese medicinal image databases, the expansion of authentication technologies, and the formation of a cultural project dedicated to the Compedium of Materia Medica. PMID:26978977

  8. Integration of Traditional Chinese Medicine and modern medicine promotes the unification of human medicine

    Directory of Open Access Journals (Sweden)

    Peng Zhang

    2010-10-01

    Full Text Available "nThere are two mutually supportive systems in medical profession: modern medicines and traditional medicine. The current status is that although the modern medicine occupies the major position in healthcare system, the therapeutic effect of traditional medicines should not be omitted. If all of them merged and unified as one, it will be beneficial to the development of human medicine. In this paper, the integration of Traditional Chinese Medicine (TCM and modern medicine was exemplified to elucidate the mutual complements, mutual benefits of traditional medicines and modern medicine to maintain the unification of human medicine via the development of molecular biology, cytology etc. We believed that TCM theory may share the same mechanism with western medicine at some extent which need to be explored in the future research. In our point of view, although the road may twist and turn, the results are promising.

  9. Theory of traditional Chinese medicine and therapeutic method of diseases

    Institute of Scientific and Technical Information of China (English)

    Ai-Ping Lu; Hong-Wei Jia; Cheng Xiao; Qing-Ping Lu

    2004-01-01

    Traditional Chinese medicine, including herbal medicine and acupuncture, as one of the most important parts in complementary and alternative medicine (CAM), plays the key role in the formation of integrative medicine. Why do not the modern drugs targeting the specificity of diseases produce theoretical effects in clinical observation? Why does not the traditional Chinese medicine targeting the Zheng (syndrome) produce theoretical effects in clinic?There should have some reasons to combine Western medicine with Chinese herbal medicine so as to form the integrative medicine. During the integration, how to clarify the impact of CAM theory on Western medicine has become an emergent topic. This paper focuses on the exploration of the impact of theory of traditional Chinese medicine on the therapy of diseases in Western medicine.

  10. Antimicrobial and antitumor activity and diversity of endophytic fungi from traditional Chinese medicinal plant Cephalotaxus hainanensis Li.

    Science.gov (United States)

    Liu, Y-H; Hu, X-P; Li, W; Cao, X-Y; Yang, H-R; Lin, S-T; Xu, C-B; Liu, S-X; Li, C-F

    2016-01-01

    Endophytes from Cephalotaxus hainanensis Li, an important source of anti-leukemia drugs, have not been widely explored. In this study, 265 endophytic fungal isolates from C. hainanensis Li were screened for antimicrobial activities against tilapia, banana, rice, and rape and for antitumor activities against human leukemia cell lines (K562, NB4, and HL-60). Diversity was also analyzed. The results showed that 17.7% of the endophytic fungi had antimicrobial activities against at least three different test microbes, and activity against Fusarium oxysporum RKY102 was the highest at 15.8%. Cytotoxicity against at least one tumor cell line tested was observed in 18.5% of the endophytic fungi; with the highest value of 10.6% against K562. The endophytic fungal strains also showed relatively high activities against K562, NB4, and HL-60 while relatively fewer strains were cytotoxic against the human hepatic Hep-G2 and colon LoVo cancer cell lines. Thirty endophytic fungal strains showed both high antimicrobial and antitumor activities. Moreover, the analyses of the diversity of the 30 highly active strains showed they belonged to 20 species from 14 genera, and this is the first report of endophytic fungi Albonectria rigidiuscula, Colletotrichum magnisporum, and Nemania diffusa being isolated from Cephalotaxus plants. These findings suggest that natural antibacterial products for humans and tilapia; antifungal compounds for rice, rape, and banana; and antitumor compounds for leukemia therapy could be isolated from fungal strains derived from C. hainanensis Li. PMID:27323030

  11. [Cultural anthropology of traditional Chinese medicine].

    Science.gov (United States)

    Wan, Xia; Liu, Jian-ping; Ai, Yan-ke; Li, Liu-ji

    2008-07-01

    Biological, psychological and sociological model of medicine substantializes the old model lacking the social humane attributes. The new medical model makes people take medical anthropology into research and highly evaluate traditional medical system. Cultural anthropology of traditional Chinese medicine (TCM) is part of medical anthropology with three major characteristics: wide research scope, specificity, and integration. It has developed its own research methods, such as field investigation, comprehensive inspection and comparison study. Cultural anthropology provides an efficient research method for TCM, and its application would further develop TCM theory and form comprehensive evaluation on TCM effects.

  12. Comparison of Traditional Chinese Medicine with Western Medicine Cancer Therapy

    Institute of Scientific and Technical Information of China (English)

    Linlin Gao; Xiongzhi Wu

    2008-01-01

    The interactions among drugs, tumor and host are critical for a response to therapy and for outcome. Anticancer herbs used in Chinese medicine are classified into 4 groups based on their target (tumor, patient and drug) as follows: eliminating pathogenic factors, strengthening the body resistance, enhancing effects of chemotherapy and detoxication of chemotherapy. Correspondingly, anticancer drugs used in Western medicine can be classified into 4 groups as follows: cytotoxic drugs, biological response modifiers, chemosensitizers and chemoprotectants.Based on the theory 0f Chinese medicinal formulas, prescriptions are composed of four constituents,namely,primary constituent(main component of the formula prescription),minister constituent(second component of formula prescription),adjuvant constituent(adjuvant component of the formula prescription)and messenger constituent(component making the formula prescription targeting pathological tissues).To control the interaction among drugs and to modulate the interaction among the tumor,patient and drugs,we suggest that combined therapy for Western medicine might include 4 constituent,i.e.,primary,cooperative,adjuvant and modulatory constituent.Cytotoxic dru gs frequently are used as primary and cooperative constituents.Whereas biological response modifiers and biochemical modu lators are usu ally regarded respectively as adjuvant drugs and modulatory constituents.We believe these new concepts may be helpful for the aim of appropriately designing.evaluating or providing combination therapy.

  13. The use of orchids in Chinese medicine

    OpenAIRE

    Bulpitt, Christopher J.; Li, Yan; Bulpitt, Pauline F; Wang, Jiguang

    2007-01-01

    In this article, the therapeutic uses of five Chinese medicines that contain orchids are discussed, together with a brief report of some of the animal experimentation undertaken. The impression that these preparations have no therapeutic use may be incorrect. However, herbal preparations have not usually been subject to the rigorous characterization and standardization necessary for clinical study, and persuading practitioners that substances in use for many centuries still need to be tested ...

  14. Proteomics and syndrome of Chinese medicine

    OpenAIRE

    Lu, Chuan-li; Qv, Xiao-Ying; Jiang, Jian-Guo

    2010-01-01

    Abstract Syndrome of Chinese medicine is an understanding of the regularity of disease occurrence and development and its performance of symptoms. Syndrome is the key to recognize diseases and the foundation to treat them. However, because of the complexity of the concept and the limitation of present investigations, the research of syndrome is hard to go further. Proteomics has been received extensive attention in the area of medical diagnosis and drug development. In the holistic and system...

  15. Traditional Chinese Medicine Induced Liver Injury

    OpenAIRE

    Teschke, Rolf

    2014-01-01

    Traditional Chinese Medicine (TCM) is popular around the world and encompasses many different practices with particular emphasis on herbal TCM. Using the PubMed database, a literature search was undertaken to assess the extent herbal TCM products exert rare hepatotoxicity. Analysis of reported cases revealed numerous specified herbal TCM products with potential hepatotoxicity. Among these were An Shu Ling, Bai Fang, Bai Xian Pi, Ban Tu Wan, Bo He, Bo Ye Qing Niu Dan, Bofu Tsu Sho San, Boh Gol...

  16. Cardiovascular Disease, Mitochondria, and Traditional Chinese Medicine

    OpenAIRE

    Jie Wang; Fei Lin; Li-li Guo; Xing-jiang Xiong; Xun Fan

    2015-01-01

    Recent studies demonstrated that mitochondria play an important role in the cardiovascular system and mutations of mitochondrial DNA affect coronary artery disease, resulting in hypertension, atherosclerosis, and cardiomyopathy. Traditional Chinese medicine (TCM) has been used for thousands of years to treat cardiovascular disease, but it is not yet clear how TCM affects mitochondrial function. By reviewing the interactions between the cardiovascular system, mitochondrial DNA, and TCM, we sho...

  17. Evidence-Based Chinese Medicine for Hypertension

    Directory of Open Access Journals (Sweden)

    Jie Wang

    2013-01-01

    Full Text Available Hypertension is an important worldwide public -health challenge with high mortality and disability. Due to the limitations and concerns with current available hypertension treatments, many hypertensive patients, especially in Asia, have turned to Chinese medicine (CM. Although hypertension is not a CM term, physicians who practice CM in China attempt to treat the disease using CM principles. A variety of approaches for treating hypertension have been taken in CM. For seeking the best evidence of CM in making decisions for hypertensive patients, a number of clinical studies have been conducted in China, which has paved the evidence-based way. After literature searching and analyzing, it appeared that CM was effective for hypertension in clinical use, such as Chinese herbal medicine, acupuncture, moxibustion, cupping, qigong, and Tai Chi. However, due to the poor quality of primary studies, clinical evidence is still weak. The potential benefits and safety of CM for hypertension still need to be confirmed in the future with well-designed RCTs of more persuasive primary endpoints and high-quality SRs. Evidence-based Chinese medicine for hypertension still has a long way to go.

  18. Patterns and Environmental Determinants of Medicinal Plant : Vascular Plant Ratios in Xinjiang, Northwest China

    Science.gov (United States)

    Zhang, Bengang; Xiao, Peigen; Qi, Yaodong; Zhang, Zhao; Liu, Haitao; Li, Xiaojin; Wang, Guoping; Terwei, André

    2016-01-01

    With both a full collection of native vascular plant distributions and a full checklist of source plants of the Chinese Materia Medica (CMM), the Uygur Medicine (UM), and the Kazak Medicine (KM) for the Xinjiang region, we defined medicinal plant: vascular plant ratios (simplified as medicinal plant ratios hereafter) as the value of medicinal plant richness divided by vascular plant richness. We aimed to find whether the ratios are constant or change in different environments, which environmental variables determine medicinal plant ratios, and whether the ratios are more influenced by human or by natural environments. Finally, suggestions for medicinal plant conservation were addressed. We found that (1) medicinal plant ratios were not constant, and they were high in the Tarim Basin which was largely covered by desert, while they were relatively low in mountainous areas, especially in the Tianshan Mountains where the general species richness was high; (2) medicinal plant ratios were not significantly influenced by human activities, indicated by human population density distributions, but they were highly correlated with plant species richness and climate, i.e. ratios decreased with plant species richness and MAP, and were related quadratically with MAT; (3) CMM ratio and UM ratio were more influenced by plant richness than by climate, while KM ratio was more influenced by climate. We concluded that the percentages of plants used as medicines were not influenced by distances from human settlements, but were determined by species richness or climate. We suggest that (1), in general, the medicinal plant ratio could be a complementary indicator for medicinal plant conservation planning and (2), for the region of Xinjiang, not only high diversity areas, but also some extreme environments should be considered as compensation for a better protection of medicinal plants. PMID:27391239

  19. Patterns and Environmental Determinants of Medicinal Plant : Vascular Plant Ratios in Xinjiang, Northwest China.

    Directory of Open Access Journals (Sweden)

    Liping Li

    Full Text Available With both a full collection of native vascular plant distributions and a full checklist of source plants of the Chinese Materia Medica (CMM, the Uygur Medicine (UM, and the Kazak Medicine (KM for the Xinjiang region, we defined medicinal plant: vascular plant ratios (simplified as medicinal plant ratios hereafter as the value of medicinal plant richness divided by vascular plant richness. We aimed to find whether the ratios are constant or change in different environments, which environmental variables determine medicinal plant ratios, and whether the ratios are more influenced by human or by natural environments. Finally, suggestions for medicinal plant conservation were addressed. We found that (1 medicinal plant ratios were not constant, and they were high in the Tarim Basin which was largely covered by desert, while they were relatively low in mountainous areas, especially in the Tianshan Mountains where the general species richness was high; (2 medicinal plant ratios were not significantly influenced by human activities, indicated by human population density distributions, but they were highly correlated with plant species richness and climate, i.e. ratios decreased with plant species richness and MAP, and were related quadratically with MAT; (3 CMM ratio and UM ratio were more influenced by plant richness than by climate, while KM ratio was more influenced by climate. We concluded that the percentages of plants used as medicines were not influenced by distances from human settlements, but were determined by species richness or climate. We suggest that (1, in general, the medicinal plant ratio could be a complementary indicator for medicinal plant conservation planning and (2, for the region of Xinjiang, not only high diversity areas, but also some extreme environments should be considered as compensation for a better protection of medicinal plants.

  20. Opening up a Way of Evaluating Evidence-based Medicine in Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Evidence-based medicine is an authoritative way of evaluating the clinical efficacy of drugs, which provides the direct evidence for clinical medication. The rise of evidence-based medical research brought about the changes in Chinese medicine from the empirical medical era into the era of evidence-based medicine. Chinese medicine, as the experience

  1. Medicinal Plants with Antiplatelet Activity.

    Science.gov (United States)

    El Haouari, Mohammed; Rosado, Juan A

    2016-07-01

    Blood platelets play an essential role in the hemostasis and wound-healing processes. However, platelet hyperactivity is associated to the development and the complications of several cardiovascular diseases. In this sense, the search for potent and safer antiplatelet agents is of great interest. This article provides an overview of experimental studies performed on medicinal plants with antiplatelet activity available through literature with particular emphasis on the bioactive constituents, the parts used, and the various platelet signaling pathways modulated by medicinal plants. From this review, it was suggested that medicinal plants with antiplatelet activity mainly belong to the family of Asteraceae, Rutaceae, Fabaceae, Lamiaceae, Zygophyllaceae, Rhamnaceae, Liliaceae, and Zingiberaceae. The antiplatelet effect is attributed to the presence of bioactive compounds such as polyphenols, flavonoids, coumarins, terpenoids, and other substances which correct platelet abnormalities by interfering with different platelet signalization pathways including inhibition of the ADP pathway, suppression of TXA2 formation, reduction of intracellular Ca(2+) mobilization, and phosphoinositide breakdown, among others. The identification and/or structure modification of the plant constituents and the understanding of their action mechanisms will be helpful in the development of new antiplatelet agents based on medicinal plants which could contribute to the prevention of thromboembolic-related disorders by inhibiting platelet aggregation. Copyright © 2016 John Wiley & Sons, Ltd. PMID:27062716

  2. [Establishment of traceability system of Chinese medicinal materials' quality].

    Science.gov (United States)

    Qi, Yao-dong; Gao, Shi-man; Liu, Hai-tao; Li, Xi-wen; Wei, Jian-he; Zhang, Ben-gang; Sun, Xiao-bo; Xiao, Pei-gen

    2015-12-01

    The quality of Chinese medicinal materials relates greatly to the clinical curative effect and security. In order to ensure the quality and safety of Chinese medicinal materials, a systematic and operable traceability system needs to be established. It can realize the whole process of quality and safety management of Chinese medicinal materials "from production to consumption" through recording and inquiring information and recalling defective products, which is an important direction for the future development of traditional Chinese medicine. But it is still at the exploration and trial stage. In this paper, a framework of Chinese medicinal materials' quality and safety traceability system was established on the basis of the domestic and international experience about the construction of food and agricultural products traceability systems. The relationship between traceability system of Chinese medicinal materials' quality and GAP, GMP, GSP was analyzed, and the possible problems and the corresponding solutions were discussed. PMID:27141688

  3. Study on the irradiation decontamination of traditional Chinese medicines

    International Nuclear Information System (INIS)

    Traditional Chinese Medicines (TCMs) are natural products prepared from plants, minerals and animals, it is easy for contamination by microorganisms to occur; thus causing problems in complying with the requirements laid down for passing microbial limit tests. We selected some kinds of TCMs, including unprocessed materia medica, traditional Chinese patent medicine (TCPMs) and chemical constituents for irradiation by 60Co gamma ray and investigating the results in terms of microbiology, chemistry, pharmacology and toxicology. We found no evidence of changes in most of the tested items, which indicates that the irradiation method could be employed for decontamination of TCMs. However, some chemical constituents of unprocessed materia medica, such as gentiopicrin in Radix Gentianae Macrophyllae and 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in Radix Polygoni Multiflori, decomposed when these crude materials were irradiated with dose of 5kGy. Further study revealed that although the medicinal were altered by irradiation, the monomers of some of these chemical constituents were not affected. In addition to investigation of the items described above, the doses of irradiation were selected experimentally to ensure that, after irradiation, the TCMs passed the microbial limit tests described in the Chinese Pharmacopoeia. The lowest possible doses were used in order to avoid any impairment of the quality and clinical efficacy of the effective ingredients of the TCMs. (author)

  4. Progress of Research in Antitumor Mechanisms with Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    韩淑燕; 李萍萍

    2009-01-01

    The anti-tumor effects of Chinese herbal medicines and their prescription preparations attracted more and more attention at home and abroad.Thus,it is becoming a hot research topic to exploit the anti-tumor mechanisms of Chinese medicine,and some of them have been partly clarified with the improved research ability to date.In brief,the Chinese herbal medicines possess unique advantages on the treatment of tumors through their multiple actions on multiple targets.

  5. Latest Progress in Tianjin Press of Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    <正>Four journals including Chinese Traditional and Herbal Drugs (CTHD), Chinese Herbal Medicines (CHM), Drugs & Clinic (DC), and Drug Evaluation Research (DER) are edited and published by Tianjin Press of Chinese Herbal Medicines. CTHD was first published in 1970 and has been playing a great role for Chinese materia medica (CMM), especially in its present modernization. CTHD has successively won several honors in recent years, such as the 2nd State

  6. Thinking and practice of accelerating transformation of traditional Chinese medicine from experience medicine to evidence-based medicine.

    Science.gov (United States)

    Liu, Baoyan; Zhang, Yanhong; Hu, Jingqing; He, Liyun; Zhou, Xuezhong

    2011-06-01

    The gradual development of Chinese medicine is based on constant accumulation and summary of experience in clinical practice, but without the benefit of undergoing the experimental medicine stage. Although Chinese medicine has formed a systematic and unique theory system through thousands of years, with the development of evidence-based medicine, the bondage of the research methods of experience medicine to Chinese medicine is appearing. The rapid transition and transformation from experience medicine to evidence-based medicine have become important content in the development of Chinese medicine. According to the features of Chinese medicine, we propose the research idea of "taking two ways simultaneously," which is the study both in the ideal condition and in the real world. Analyzing and constructing the theoretical basis and methodology of clinical research in the real world, and building the stage for research technique is key to the effective clinical research of Chinese medicine. Only by gradually maturing and completing the clinical research methods of the real world could we realize "taking two ways simultaneously" and complementing each other, continuously produce scientific and reliable evidence of Chinese medicine, as well as transform and develop Chinese medicine from experience medicine to evidence-based medicine. PMID:21695621

  7. [Technical standards of traditional Chinese medicine industry].

    Science.gov (United States)

    Wang, Guangping; Song, Jinqi

    2010-06-01

    Basing on the basic theory of traditional Chinese medicine (TCM), the technical standards of TCM industry is such a Link that it is to clarify the internal relations between the basic theory of TCM and developing of TCM industry. This article analyzed several problems of technical standards of TCM industry, such as basic theory of TCM and standardization problem of TCM industry. Technical standards of TCM industry must receive the guidance of basic theory of TCM, so that it will promote the process of modernization and internationalization of TCM industry.

  8. [Treatment of senile diseases should prescribe Chinese patent medicine scientifically].

    Science.gov (United States)

    Zhao, Xin-Xiang

    2014-04-01

    Treatment of senile diseases by Chinese patent medicine should prescribe according to physiological and pathological specialty of the aged. It's necessary for treatment according to syndrome differentiation associating with the disease,reasonable combination of drugs avoiding adverse reactions,gentle medicine character but not fierce,small medicine quantity but not great, the use of Chinese patent medicine mild and tonic used properly but not excessively. PMID:24812911

  9. Chemometrics and modernization of traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Development of chromatographic fingerprinting and its related chemometric methods in the research of quality control of traditional Chinese medicines(TCMs) are discussed. The quality control methods for guarantying the authentication and stability of products and semi-products of TCMs are firstly assessed. The technique based on chromatographic fingerprinting is essentially a kind of high-through put and integral tools to explore the complexity of herbal medicines. In order to further control the comprehensive quality of TCMs,confirmation and identification of their important chemical components are necessary. Some new strategies are proposed to trace the chemical changes of chromatographic fingerprints both in product processing and/or after their administration by modern chromatographic techniques and chemometrics. Combined with systems biology and bioinformatics,it seems possible for one to reveal the working mechanism of TCMs and to further control their intrinsic quality comprehensively.

  10. [Where will Chinese medicine disease names go?].

    Science.gov (United States)

    Su, Zhan-Qing

    2013-06-01

    The statistical survey of "Clinical Articles", one column of Journal of Traditional Chinese Medicine (24 volumes in total) showed that, of the 151 academic exploration on diseases, Western disease (WM) names were used in 145 articles, constituting 96.03% of the entire column. Obviously, Chinese medicine (CM) disease names were not basically used by CM physicians. Taking Chinese Internal Medicine (2nd edition), a national textbook for students in CM universities, as an example, we could find that the use of disease names was in a chaos logically, disease, syndrome, and symptom were not used clearly. In the general knowledge part, when mentioning a disease, the book sometimes used "disease", sometimes "disease-syndrome". In the classified parts, some diseases were simply named as "A or B syndrome", and when talking about a specific disease, it referred to the symptom-based disease as a kind of "disease-syndrome". Throughout the whole book, the disease names named after symptoms or heavily colored by symptoms amounted to 31, accounting for 59.6% of the listed 52 common diseases. In clinical practices, using CM disease names ran the risk of making wrong diagnosis or failing to diagnose patients in time, and therefore, leading to improper treatment or loss of treatment time. For critical diseases, these names can't reveal the serious situations and help to get rid of possible dangers. For chronic diseases, using these names can't lead to early recognition and prevention of diseases. Considering that CM disease names can't go with clinical practices, and lag behind the development of integrative medicine, the author suggested that we should borrow as many WM disease names as possible in CM, because when compared with CM, WM has a much clearer and more objective knowledge of the location, cause, mechanisms, diagnosis, treatment, and prevention of diseases. The classification and naming of diseases in WM is the result of negotiation of WHO and its member countries

  11. [Where will Chinese medicine disease names go?].

    Science.gov (United States)

    Su, Zhan-Qing

    2013-06-01

    The statistical survey of "Clinical Articles", one column of Journal of Traditional Chinese Medicine (24 volumes in total) showed that, of the 151 academic exploration on diseases, Western disease (WM) names were used in 145 articles, constituting 96.03% of the entire column. Obviously, Chinese medicine (CM) disease names were not basically used by CM physicians. Taking Chinese Internal Medicine (2nd edition), a national textbook for students in CM universities, as an example, we could find that the use of disease names was in a chaos logically, disease, syndrome, and symptom were not used clearly. In the general knowledge part, when mentioning a disease, the book sometimes used "disease", sometimes "disease-syndrome". In the classified parts, some diseases were simply named as "A or B syndrome", and when talking about a specific disease, it referred to the symptom-based disease as a kind of "disease-syndrome". Throughout the whole book, the disease names named after symptoms or heavily colored by symptoms amounted to 31, accounting for 59.6% of the listed 52 common diseases. In clinical practices, using CM disease names ran the risk of making wrong diagnosis or failing to diagnose patients in time, and therefore, leading to improper treatment or loss of treatment time. For critical diseases, these names can't reveal the serious situations and help to get rid of possible dangers. For chronic diseases, using these names can't lead to early recognition and prevention of diseases. Considering that CM disease names can't go with clinical practices, and lag behind the development of integrative medicine, the author suggested that we should borrow as many WM disease names as possible in CM, because when compared with CM, WM has a much clearer and more objective knowledge of the location, cause, mechanisms, diagnosis, treatment, and prevention of diseases. The classification and naming of diseases in WM is the result of negotiation of WHO and its member countries

  12. Protecting traditional knowledge of Chinese medicine: concepts and proposals.

    Science.gov (United States)

    Liu, Changhua; Gu, Man

    2011-06-01

    With the development of the knowledge economy, knowledge has become one of the most important resources for social progress and economic development. Some countries have proposed measures for the protection of their own traditional knowledge. Traditional Chinese medicine belongs to the category of intangible cultural heritage because it is an important part of Chinese cultural heritage. Today the value of traditional knowledge of Chinese medicine has been widely recognized by the domestic and international public. This paper discusses the definition of traditional knowledge of Chinese medicine and its protection, and evaluates research on its classification. We review the present status of the protection of traditional knowledge of Chinese medicine and tentatively put forward some possible ideas and methods for the protection of traditional knowledge of Chinese medicine. Our goal is to find a way to strengthen the vitality of traditional Chinese medicine and consolidate its foundation. We believe that if we could establish a suitable sui generis(sui generis is a Latin term meaning "of its own kind" and is often used in discussions about protecting the rights of indigenous peoples. Here we use it to emphasize the fact that protection of traditional knowledge of Chinese medicine cannot be achieved through existing legal means of protection alone due to its unique characteristics) system for traditional knowledge, a more favorable environment for the preservation and development of traditional Chinese medicine will ultimately be created. PMID:21695628

  13. Protecting traditional knowledge of Chinese medicine: concepts and proposals.

    Science.gov (United States)

    Liu, Changhua; Gu, Man

    2011-06-01

    With the development of the knowledge economy, knowledge has become one of the most important resources for social progress and economic development. Some countries have proposed measures for the protection of their own traditional knowledge. Traditional Chinese medicine belongs to the category of intangible cultural heritage because it is an important part of Chinese cultural heritage. Today the value of traditional knowledge of Chinese medicine has been widely recognized by the domestic and international public. This paper discusses the definition of traditional knowledge of Chinese medicine and its protection, and evaluates research on its classification. We review the present status of the protection of traditional knowledge of Chinese medicine and tentatively put forward some possible ideas and methods for the protection of traditional knowledge of Chinese medicine. Our goal is to find a way to strengthen the vitality of traditional Chinese medicine and consolidate its foundation. We believe that if we could establish a suitable sui generis(sui generis is a Latin term meaning "of its own kind" and is often used in discussions about protecting the rights of indigenous peoples. Here we use it to emphasize the fact that protection of traditional knowledge of Chinese medicine cannot be achieved through existing legal means of protection alone due to its unique characteristics) system for traditional knowledge, a more favorable environment for the preservation and development of traditional Chinese medicine will ultimately be created.

  14. Phytochemical constituents of some Indian medicinal plants

    OpenAIRE

    Dhandapani, R.; Sabna, B.

    2008-01-01

    Alkaloids, tannins, saponins, steroid, terpenoid, flavonoids, phlobatannin and cardie glycoside distribution in seven medicinal plants belonging to different families were assessed and compared. The medicinal plants investigated were Aegle marmelos, Cynodon dactylon, Eclipta prostrata, Moringa pterygosperma, Pongamia pinnata, Sida acuta and Tridax procumbens. The significance of the plants in traditional medicine and the importance of the distribution of these chemical constituents were discu...

  15. Chinese herbal medicine for severe acute respiratory syndrome

    DEFF Research Database (Denmark)

    Liu, Jianping; Manheimer, Eric; Shi, Yi;

    2004-01-01

    To review randomized controlled trials (RCTs) evaluating the effects of Chinese herbal medicine for treating severe acute respiratory syndrome (SARS) systematically.......To review randomized controlled trials (RCTs) evaluating the effects of Chinese herbal medicine for treating severe acute respiratory syndrome (SARS) systematically....

  16. Chinese Medicine: A Cognitive and Epistemological Review

    Directory of Open Access Journals (Sweden)

    Ben Kavoussi

    2007-01-01

    Full Text Available In spite of the common belief that Chinese natural philosophy and medicine have a unique frame of reference completely foreign to the West, this article argues that they in fact have significant cognitive and epistemic similarities with certain esoteric health beliefs of pre-Christian Europe. From the standpoint of Cognitive Science, Chinese Medicine appears as a proto-scientific system of health observances and practices based on a symptomological classification of disease using two elementary dynamical-processes pattern categorization schemas: a hierarchical and combinatorial inhibiting–activating model (Yin-Yang, and a non-hierarchical and associative five-parameter semantic network (5-Elements/Agents. The concept-map of the five-parameter model amounts to a pentagram, a commonly found geomantic and spell casting sigil in a number of pre-Christian health and safety beliefs in Europe, to include the Pythagorean cult of Hygieia, and the Old Religion of Northern Europe. This non-hierarchical pattern-recognition archetype/prototype was hypothetically added to the pre-existing hierarchical one to form a hybrid nosology that can accommodate for a change in disease perceptions. The selection of five parameters rather than another number might be due to a numerological association between the integer five, the golden ratio, the geometry of the pentagram and the belief in health and wholeness arising from cosmic or divine harmony. In any case, this body of purely empirical knowledge is nowadays widely flourishing in the US and in Europe as an alternative to Western Medicine and with the claim of being a unique, independent and comprehensive medical system, when in reality it is structurally—and perhaps historically—related to the health and safety beliefs of pre-Christian Europe; and without the prospect for an epistemological rupture, it will remain built upon rudimentary cognitive modalities, ancient metaphysics, and a symptomological view of

  17. Challenges in Research and Development of Traditional Chinese Medicines

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    This review is briefly to recall the history of research and development (R&D) of Chinese materia medica (CMM) and to discuss the challenges of Chinese traditional and herbal medicines (CTHM) facing the modern science and technology. The R&D of CTHM is thought to be an important pathway for new drug discovery. Since1949, about 140 approved new drugs have been developed, among which about 80 originated directly or indirectly from medicinal plants. CTHM has gained interest from the international medical, biomedical, and pharmaceutical institutions as a valuable source of potential medicines. For the modernization of CMM and innovative research of CTHM, there are following challenges to be faced: (1) to evaluate the efficacy, pharmacological properties, action mechanism, and active chemical constituents; (2) to develop new methodologies for the quality and safety of CTHM; (3) to apply new "-omics" techniques to accelerate drug discoveries developed from CTHM; and (4) to apply international practices including good agricultural practice, good manufacturing practice, good laboratory practice, and good clinical practice in the R&D of CTHM.

  18. The quest for modernisation of traditional Chinese medicine

    OpenAIRE

    Xu, Qihe; Bauer, Rudolf; Hendry, Bruce M.; Fan, Tai-Ping; Zhao, Zhongzhen; Duez, Pierre; Simmonds, Monique SJ; Witt, Claudia M.; Lu, Aiping; Robinson, Nicola; Guo, De-an; Hylands, Peter J.

    2013-01-01

    Abstract Traditional Chinese medicine (TCM) is an integral part of mainstream medicine in China. Due to its worldwide use, potential impact on healthcare and opportunities for new drug development, TCM is also of great international interest. Recently, a new era for modernisation of TCM was launched with the successful completion of the Good Practice in Traditional Chinese Medicine Research in the Post-genomic Era (GP-TCM) project, the European Union’s Seventh Framework Programme (FP7) ...

  19. The compatibility of patent law and traditional Chinese medicine

    OpenAIRE

    Chen, Yifu; 陈一孚

    2013-01-01

    Traditional Chinese Medicine (TCM) is a medical system with a unique medical philosophy that continues to guide the contemporary turning out of new pharmaceutical formulae. The clinically-proved effective components of these formulae are being extracted by means of modern technology. Natural Chinese medicines account for approximately 30% of the global sales volume of all medicines, and the international market-size of the TCM industry is increasing rapidly. The TCM industry depends on the p...

  20. [Theoretical model for compatibility of medicinal property combination of traditional Chinese medicines].

    Science.gov (United States)

    Sun, Jing; Zhang, Yan-ling; Gu, Hao; Wang, Yun

    2015-08-01

    Medicinal properties are specific attributes of traditional Chinese medicines(TCM). The medicinal property theory is an important principle for the compatibility of traditional Chinese medicines. In this paper, medicinal properties, flavors and meridian tropism were combined to represent TCM medicinal properties; and multiple medicinal properties were further combined into medicinal property combination modes. TCMs and medicinal property combination modes were divided according to their efficacies, which were regarded as the concept of inductive logic programming and finally got medicinal property combination and compatibility rules with different efficacies. These medicinal property combination and compatibility rules were used to form the theoretical model through the entity grammar system, realize the automatic reasoning process from the medicinal property combination and compatibility to the efficacies, verify the reasoning result and analyze their rationality and limitations, in order to provide new ideas for revealing the relations between the TCM compatibility rules and efficacies. PMID:26790316

  1. Phytochemical constituents of some Indian medicinal plants.

    Science.gov (United States)

    Dhandapani, R; Sabna, B

    2008-04-01

    Alkaloids, tannins, saponins, steroid, terpenoid, flavonoids, phlobatannin and cardie glycoside distribution in seven medicinal plants belonging to different families were assessed and compared. The medicinal plants investigated were Aegle marmelos, Cynodon dactylon, Eclipta prostrata, Moringa pterygosperma, Pongamia pinnata, Sida acuta and Tridax procumbens. The significance of the plants in traditional medicine and the importance of the distribution of these chemical constituents were discussed with respect to the role of these plants in ethnomedicine in India. PMID:22557280

  2. Cardiovascular Disease, Mitochondria, and Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Jie Wang

    2015-01-01

    Full Text Available Recent studies demonstrated that mitochondria play an important role in the cardiovascular system and mutations of mitochondrial DNA affect coronary artery disease, resulting in hypertension, atherosclerosis, and cardiomyopathy. Traditional Chinese medicine (TCM has been used for thousands of years to treat cardiovascular disease, but it is not yet clear how TCM affects mitochondrial function. By reviewing the interactions between the cardiovascular system, mitochondrial DNA, and TCM, we show that cardiovascular disease is negatively affected by mutations in mitochondrial DNA and that TCM can be used to treat cardiovascular disease by regulating the structure and function of mitochondria via increases in mitochondrial electron transport and oxidative phosphorylation, modulation of mitochondrial-mediated apoptosis, and decreases in mitochondrial ROS. However further research is still required to identify the mechanism by which TCM affects CVD and modifies mitochondrial DNA.

  3. [A brief history of traditional Chinese medicinal pills].

    Science.gov (United States)

    Xu, X; Lu, X; Zhu, J P

    2016-05-01

    Traditional Chinese medicine pill, an archaic medicinal preparation form, is a kind of spherical or spherical-like preparation form produced by medicinal powders or extracts mixed with appropriate excipient or other accessories. It was originated in the Pre-Qin Dynasty, developed and enriched from the Han Dynasty to the Ming and Qing Dynasties. With the improvement of preparing process, honeyed pill, waxed pill, coating pill and wax-coating pill etc. appeared in succession. In modern times, with the progress of pharmaceutical machine, the medicinal pill is innovated constantly, and at present, it becomes the main form of Chinese patent medicine with batch production. PMID:27485865

  4. Radiation protection by medicinal plants

    International Nuclear Information System (INIS)

    The development of effective non-toxic radioprotective agents is of considerable interest in the improvement of radiotherapy of cancer and protection against unplanned exposures. The synthetic drugs developed in post-world war II have had serious constrains in clinical applicable due to their toxicity at the optimal protective dose. Search for non-toxic protectors from natural sources have indicated that some of the commonly used medicinal plants and the poly herbal formulation could prove to be valuable sources of clinically useful radioprotectors as their ratio of effective dose to toxic dose is very high

  5. The effect of Morinda officinalis How, a Chinese traditional medicinal plant, on the DRL 72-s schedule in rats and the forced swimming test in mice.

    Science.gov (United States)

    Zhang, Zhong-Qi; Yuan, Li; Yang, Ming; Luo, Zhi-Pu; Zhao, Yi-Min

    2002-05-01

    The present study observed the antidepressant-like action of the medicinal plant Morinda officinalis in the differential reinforcement of low rate 72-s (DRL 72-s) schedule, a behavioral screen selective and sensitive to antidepressant drugs, and the forced swimming test, a well-known animal model of depression. In the DRL 72-s schedule in rats, the plant extract (25-50 mg/kg), similar to clinically effective antidepressant drug desipramine (5-10 mg/kg), significantly reduced response rate and efficiency ratio while at the same time increasing reinforcement rate. In the forced swimming test in mice, the plant extract (50 mg/kg), like the effect of desipramine (20 mg/kg), also elicited a significant reduction in the duration of immobility. A tendency to this phenomenon could be seen at the dose of 100 mg/kg. Meanwhile, the plant extract, in the effective doses for the forced swimming test, had no effects on spontaneous motor activity in mice. These findings provide further support for the conclusion that M. officinalis extract possesses the antidepressant effect. PMID:11900767

  6. Pharmacokinetics Applications of Traditional Chinese Medicines

    Institute of Scientific and Technical Information of China (English)

    Qiu-Ju Li; Ai-Hua Zhang; Hui Sun; Xi-Jun Wang

    2016-01-01

    Traditional Chinese medicine (TCM) has been widely used in many oriental countries for thousands of years and played an indispensable role in the prevention and treatment of diseases, especially the complicated and chronic ones. It is a very complex mixture containing hundreds or thousands of different components. Pharmacokinetic study on active constituents in TCM preparations is a good way for us to explain and predict a variety of events related to the efficacy and toxicity of TCM. In the drug discovery phases, pharmacokinetics is a key to guide medicinal chemists in the optimization process of a chemical series and to assist pharmacologists to design in vivo studies. To explore the potentially bioactive components in TCM, it is necessary to further study the in vivo pharmacokinetic characteristics of multiple absorbed components and find out the optical time-course behavior to providing more substantial research for new leads in drug discovery. Pharmacokinetics screening method could provide a reliable means of prospecting natural products in the search for new leads in drug discovery. This review summarizes the research progress of PK on TCM in the search for suitable lead compounds in recent years.

  7. Traditional Chinese Medicine for Chronic Fatigue Syndrome

    Directory of Open Access Journals (Sweden)

    Rui Chen

    2010-01-01

    Full Text Available More and more patients have been diagnosed as having chronic fatigue syndrome (CFS in recent years. Western drug use for this syndrome is often associated with many side-effects and little clinical benefit. As an alternative medicine, traditional Chinese medicine (TCM has provided some evidences based upon ancient texts and recent studies, not only to offer clinical benefit but also offer insights into their mechanisms of action. It has perceived advantages such as being natural, effective and safe to ameliorate symptoms of CFS such as fatigue, disordered sleep, cognitive handicaps and other complex complaints, although there are some limitations regarding the diagnostic standards and methodology in related clinical or experimental studies. Modern mechanisms of TCM on CFS mainly focus on adjusting immune dysfunction, regulating abnormal activity in the hypothalamic-pituitary-adrenal (HPA axis and serving as an antioxidant. It is vitally important for the further development to establish standards for ‘zheng’ of CFS, i.e. the different types of CFS pathogenesis in TCM, to perform randomized and controlled trials of TCM on CFS and to make full use of the latest biological, biochemical, molecular and immunological approaches in the experimental design.

  8. The Origin of Traditional Chinese Medicine and Thinking on Chinese Medicine Development

    Institute of Scientific and Technical Information of China (English)

    Wang Wenkui; Wang Feng; Wang Ling

    2006-01-01

    Although the traditional Chinese medicine (TCM) has developed a profound theory system and a fame of outstanding advantage in curative effect, it seems that the TCM is not quite adaptable to the deveiopment and requirement of the modern society. A principle of "Adopting the advanced part of Western medicine to serve the TCM" should be adhered to for the traditional Chinese medicine. First, TCM should strive for a consensus of TCM theory which focuses on the guiding principles of "diagnosis and treatment based on an overall analysis of the illness and the patient's condition" and "the opposite principle of five internal organs". Among these principles, "keeping relative balance of three internal systems"is a valuable guidance of the diagnosis and treatment theory. Secondly, macroscopic should be integrated with microscopic, totality with parts, phenomenology with materialism. A dialectical law should be applied to guide analysis. In treatment,adjustment and balance are basic principles. It is necessary not only prepare the medicine in advance accoding to the predicted disease of the year, but also adopt methods to restrict disease in advance. Basides, TCM dose type should be ameliorated in order to meet the needs of society.

  9. Some medicinal plants as natural anticancer agents

    Directory of Open Access Journals (Sweden)

    Govind Pandey

    2009-01-01

    Full Text Available India is the largest producer of medicinal plants and is rightly called the "Botanical garden of the World". The medicinal plants, besides having natural therapeutic values against various diseases, also provide high quality of food and raw materials for livelihood. Considerable works have been done on these plants to treat cancer, and some plant products have been marketed as anticancer drugs, based on the traditional uses and scientific reports. These plants may promote host resistance against infection by re-stabilizing body equilibrium and conditioning the body tissues. Several reports describe that the anticancer activity of medicinal plants is due to the presence of antioxidants in them. In fact, the medicinal plants are easily available, cheaper and possess no toxicity as compared to the modern (allopathic drugs. Hence, this review article contains 66 medicinal plants, which are the natural sources of anticancer agents.

  10. [The plant origins of herbal medicines and their quality evaluation].

    Science.gov (United States)

    Nishibe, Sansei

    2002-06-01

    The caulis (stem and leaf) of Trachelospermum jasminoides (Lindl.) Lem. (Apocynaceae) is listed as the plant origin of Luoshiteng in the Chinese Pharmacopeia. However, preparations from the caulis of Ficus pumila L. (Moraceae) or Psychotria serpens L. (Rubiaceae) are distributed on the Chinese market. The fruit of Forsythia suspensa Vahl (Oleaceae) is listed as the plant origin of Forsythia Fruit in the Chinese Pharmacopeia, although the fruits of two Forsythia species, F. suspensa and F. viridissima Lindley, are listed as the plant origins in the Japanese Pharmacopeia, and fruits of three Forsythia species, F. viridissima, F. koreana Nakai, and F. suspensa, are listed in the Korean Pharmacopeia. The whole plant of Plantago asiatica L. (Plantaginaceae) is listed as the plant origin of Plantago Herb in the Japanese Phamacopeia, but the whole plants of two Plantago species, P. asiatica and P. depressa Wild, are listed as the plant origins in the Chinese Pharmacopeia. The leaves of two Plantago species, P. lanceolata L. and P. major L., are distributed as Plantain on the European market. Each of these herbal medicines is reviewed based on the differences in plant origins and their quality evaluation from the viewpoints of the morphological properties, chemical components, and biological activities, respectively.

  11. Some medicinal plants as natural anticancer agents

    OpenAIRE

    Govind Pandey; S Madhuri

    2009-01-01

    India is the largest producer of medicinal plants and is rightly called the "Botanical garden of the World". The medicinal plants, besides having natural therapeutic values against various diseases, also provide high quality of food and raw materials for livelihood. Considerable works have been done on these plants to treat cancer, and some plant products have been marketed as anticancer drugs, based on the traditional uses and scientific reports. These plants may promote host resistance agai...

  12. Summary of the 2008 Evidence-based Chinese Medicine(EBCM) Workshop

    Institute of Scientific and Technical Information of China (English)

    吴大嵘; 赖世隆; 杨显荣

    2009-01-01

    The 2008 Evidence-based Chinese Medicine (EBCM) Workshop,jointly organized by the International Society for Chinese Medicine/Editorial Board of Chinese Medicine(Macao) and the Guangdong Provincial Hospital of Chinese Medicine/ Second Affiliated Hospital of Guangzhou University of

  13. Medicinal plants with hepatoprotective activity in Iranian folk medicine

    Directory of Open Access Journals (Sweden)

    Majid Asadi-Samani

    2015-02-01

    Full Text Available There are a number of medicinal combinations in the Iranian traditional medicine which are commonly used as tonic for liver. In this review, we have introduced some medicinal plants that are used mainly for the treatment of liver disorders in Iranian folk medicine, with focus on their hepatoprotective effects particularly against CC14 agent. In this study, online databases including Web of Science, PubMed, Scopus, and Science Direct were searched for papers published from January 1970 to December 2013. Search terms consisted of medicinal plants, traditional medicine, folk medicine, hepatoprotective, Iran, liver, therapeutic uses, compounds, antioxidant, CC14, anti-inflammatory, and antihepatotoxic, hepatitis, alone or in combination. Allium hirtifolium Boiss., Apium graveolens L., Cynara scolymus, Berberis vulgaris L., Calendula officinalis, Nigella sativa L., Taraxacum officinale, Tragopogon porrifolius, Prangos ferulacea L., Allium sativum, Marrubium vulgare, Ammi majus L., Citrullus lanatus Thunb, Agrimonia eupatoria L. and Prunus armeniaca L. are some of the medicinal plants that have been used for the treatment of liver disorders in Iranian folk medicine. Out of several leads obtained from plants containing potential hepatoprotective agents, silymarin, β-sitosterol, betalain, neoandrographolide, phyllanthin, andrographolide, curcumin, picroside, hypophyllanthin, kutkoside, and glycyrrhizin have been demonstrated to have potent hepatoprotective properties. Despite encouraging data on possibility of new discoveries in the near future, the evidence on treating viral hepatitis or other chronic liver diseases by herbal medications is not adequate.

  14. [Study on dosage form design for improving oral bioavailability of traditional Chinese medicines].

    Science.gov (United States)

    Xia, Hai-Jian; Zhang, Zhen-Hai; Yao, Dong-Dong; Jia, Xiao-Bin

    2013-09-01

    Both chemical drugs and traditional Chinese medicines have the problem of low bioavailability. However, as traditional Chinese medicines are a multi-component complex, their dosage forms are required to be designed in line with their characteristics, in order to improve the bioavailability of traditional Chinese medicines. Traditional Chinese medicines are mostly prepared into pill, powder, paste, elixir and decoction, but with such drawbacks as high administration dose and poor efficacy. With the process of modernization of traditional Chinese medicines, new-type preparations have be developed and made outstanding achievements. However, they fail to make an organic integration between traditional Chinese medicine theories and modern preparation theories. Characteristics of traditional Chinese medicines are required to be taken into account during the development of traditional Chinese medicines. In the article, multi-component preparation technology was adopted to establish a multi-component drug release system of traditional Chinese medicines on the basis of multiple components of traditional Chinese medicines.

  15. Traditional Chinese Medicine in the Prevention of Disease

    Directory of Open Access Journals (Sweden)

    Claudia Patricia Ardila Jaimes

    2015-05-01

    Full Text Available Introduction: Traditional Chinese medicine is based on the oriental philosophy developed thousands of years ago, their understanding involves a deep understanding and knowledge of it. Materials and methods: This article seeks to reflect on the philosophy behind Chinese medicine and the role it has played in preventing the disease. Results: Three perspectives related to the philosophical foundations of traditional Chinese medicine and prevention analysis, the rise and popularity of its use in the prevention and the role of science in strengthening the evidence in the therapeutic of Traditional Chinese Medicine addresses. Conclusion: The contribution of TCM to the prevention of diseases can be magnified to the extent that their study will expand and further substantiate its effectiveness.

  16. How does Chinese medicine target cytokine imbalance in rheumatoid arthritis?

    Science.gov (United States)

    Liu, Jian; Sun, Yue

    2013-11-01

    Rheumatoid arthritis (RA) manifests as an imbalance between pro- and anti-inflammatory cytokines. Cytokine imbalance is suggested to play critical roles in the development of RA. Currently, various treatments for RA, including biological agents such as antibodies against inflammation mediators, or Chinese herbal medicines, intervene the disease by restoring the balance of cytokines. Chinese medicine (CM) can not only suppress the expression of pro-inflammatory cytokines, but also induce the expression of cytokines with anti-inflammatory and immunomodulatory effects. Thus, Chinese medicine can effectively reduce inflammatory cell infiltration into synovial tissue, pannus formation, and degradation of the extracellular matrix surrounding cartilage cells, thereby reducing subchondral bone damage. This paper reviews the changes of cytokine profiling during development of RA and discuss the mechanisms by which Chinese medicine restores the cytokine balance.

  17. How does Chinese medicine target cytokine imbalance in rheumatoid arthritis?

    Science.gov (United States)

    Liu, Jian; Sun, Yue

    2013-11-01

    Rheumatoid arthritis (RA) manifests as an imbalance between pro- and anti-inflammatory cytokines. Cytokine imbalance is suggested to play critical roles in the development of RA. Currently, various treatments for RA, including biological agents such as antibodies against inflammation mediators, or Chinese herbal medicines, intervene the disease by restoring the balance of cytokines. Chinese medicine (CM) can not only suppress the expression of pro-inflammatory cytokines, but also induce the expression of cytokines with anti-inflammatory and immunomodulatory effects. Thus, Chinese medicine can effectively reduce inflammatory cell infiltration into synovial tissue, pannus formation, and degradation of the extracellular matrix surrounding cartilage cells, thereby reducing subchondral bone damage. This paper reviews the changes of cytokine profiling during development of RA and discuss the mechanisms by which Chinese medicine restores the cytokine balance. PMID:24170633

  18. Application of microdialysis technique in the traditional chinese medicine

    DEFF Research Database (Denmark)

    Zhang, Shaomin; Zeng, Xianghui; Xu, Xiaohong;

    2005-01-01

    The concentration of extracellular neurotransmitters can be dynamically measured by in vivo microdialysis. This technique can apply to quantitatively evaluating the beneficial effects of Traditional Chinese Medicine (TCM). In the present study, the protective effects of Puerarin (Pur) on cerebral...

  19. Sustainable Utilization of Traditional Chinese Medicine Resources: Systematic Evaluation on Different Production Modes

    Directory of Open Access Journals (Sweden)

    Xiwen Li

    2015-01-01

    Full Text Available The usage amount of medicinal plant rapidly increased along with the development of traditional Chinese medicine industry. The higher market demand and the shortage of wild herbal resources enforce us to carry out large-scale introduction and cultivation. Herbal cultivation can ease current contradiction between medicinal resources supply and demand while they bring new problems such as pesticide residues and plant disease and pests. Researchers have recently placed high hopes on the application of natural fostering, a new method incorporated herbal production and diversity protecting practically, which can solve the problems brought by artificial cultivation. However no modes can solve all problems existing in current herbal production. This study evaluated different production modes including cultivation, natural fostering, and wild collection to guide the traditional Chinese medicine production for sustainable utilization of herbal resources.

  20. Phytochemical Analysis of Some Traditional Medicinal Plants

    Directory of Open Access Journals (Sweden)

    V. Nandagoapalan

    2016-01-01

    Full Text Available Screening of phytochemicals is a precious stair in the detection of bioactive principles present in particular medicinal plant and may lead to novel drug discovery. In the present study, principal phytoconstituents of 25 traditional medicinal plants were identified in order to relate their presence with bioactivities of the plants. Screening of the plants was performed using standard methods and resulted in the detection of the presence of tannins, flavonoids, phenolics, saponins, steroids, cardiac glycosides and alkaloids. Flavonoids were present in 19 of 25 plants while alkaloids were present in sixteen plants. The presence of these phytochemicals can be correlated with medicinal potential of these plants. Further studies are needed with these plants to evaluate their pharmacological potentials, isolate, characterize and elucidate the structures of the bioactive compounds responsible for their activities and other medicinal values.

  1. Conservation of medicinal and aromatic plants

    Directory of Open Access Journals (Sweden)

    Šveistytė, Laima

    2016-07-01

    Full Text Available The conservation of medicinal and aromatic plants includes ex situ and in situ methods. The genetic recourses of medicinal and aromatic plants are stored, studied and constantly maintained in the field collections of the Institute of Botany of Nature Research Centre, Kaunas Botanical Garden of Vytautas Magnus University and Aleksandras Stulginskis University of Agriculture. Presently seeds of 214 accessions representing 38 species of medicinal and aromatic plants are stored in a long-term storage in the Plant Gene Bank. The data about national genetic resources are collected and stored in the Central Database of the Plant Gene Bank.

  2. Medicinal plant markets and trade in Maputo, Mozambique

    DEFF Research Database (Denmark)

    Krog, Mogens Pedersen; Falcâo, Mario P.; Olsen, Carsten Smith

    Medicinal plants and traditional medicine are important to urban and rural livelihoods in Mozambique. This study presents a preliminary investigation of the structure and conduct of medicinal plant markets in Maputo.......Medicinal plants and traditional medicine are important to urban and rural livelihoods in Mozambique. This study presents a preliminary investigation of the structure and conduct of medicinal plant markets in Maputo....

  3. Traditional Chinese Medicine for Senile Dementia

    Directory of Open Access Journals (Sweden)

    Zhihong Lin

    2012-01-01

    Full Text Available Traditional Chinese Medicine (TCM has a 3000 years' history of human use. A literature survey addressing traditional evidence from human studies was done, with key result that top 10 TCM herb ingredients including Poria cocos, Radix polygalae, Radix glycyrrhizae, Radix angelica sinensis, and Radix rehmanniae were prioritized for highest potential benefit to dementia intervention, related to the highest frequency of use in 236 formulae collected from 29 ancient Pharmacopoeias, ancient formula books, or historical archives on ancient renowned TCM doctors, over the past 10 centuries. Based on the history of use, there was strong clinical support that Radix polygalae is memory improving. Pharmacological investigation also indicated that all the five ingredients mentioned above can elicit memory-improving effects in vivo and in vitro via multiple mechanisms of action, covering estrogen-like, cholinergic, antioxidant, anti-inflammatory, antiapoptotic, neurogenetic, and anti-Aβ activities. Furthermore, 11 active principles were identified, including sinapic acid, tenuifolin, isoliquiritigenin, liquiritigenin, glabridin, ferulic acid, Z-ligustilide, N-methyl-beta-carboline-3-carboxamide, coniferyl ferulate and 11-angeloylsenkyunolide F, and catalpol. It can be concluded that TCM has a potential for complementary and alternative role in treating senile dementia. The scientific evidence is being continuously mined to back up the traditional medical wisdom.

  4. [HRM identification of Chinese medicinal materials Mutong].

    Science.gov (United States)

    Hu, Jun; Zhan, Zhi-lai; Yuan, Yuan; Huang, Lu-qi; Liu, Yong

    2015-06-01

    High resolution melting (HRM), an important technology for genotyping and mutation scanning, has broad prospects in the authentification of traditional Chinese medicine. This paper selected universal trnH-psbA primers and used HRM to establish a new methods for identification of Akebia herbs. PCR was conduct at the annealing temperature of 58 degrees C and 35 cycles. The range of the DNA template concentration, the primer concentration and the Mg2+ ion concentration were further analyzed. The results showed the Tm values of Caulis Akebiae was (81.84 ± 0.16), (85.28 ± 0.16) degrees C and Caulis Clematidis Armandii was (83.22 ± 0.19) degrees C and Caulis Aristolochiae manshuriensis was (81.67 ± 0.14) degrees C, (84.24 ± 0.10) degrees C with 5-125 mg - L-' DNA template, 0.4 μmol x L(-1) primer, 2.0 mmol x L(-1) Mg2+. This method can achieve the authentification of Akebia herbs and is simple, fast, high-throughput, visual. PMID:26591514

  5. THE NEW YEAR MESSAGE FROM CHINESE JOURNAL OF INTEGRATIVE MEDICINE

    Institute of Scientific and Technical Information of China (English)

    陈可冀

    2003-01-01

    @@ Two months into the year 2003 and one month into the Chinese lunar New Year of goat, on behalf of the editorial board of the Chinese Journal of Integrative Medicine, I wish our readers, contributors and board members around the world a prosperous and successful new year.

  6. Opening up a Way of Evaluating Evidence-based Medicine in Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    JIA Zhen-hua

    2009-01-01

    @@ dence-based medicine is an authoritative way of evaluating the clinical efficacy of drugs,which provides the direct evidence for clinical medication.The rise of evidence-based medical research brought about the changes in Chinese medicine from the empirical medical era into the era of evidence-based medicine.

  7. From Curanderas to Gas Chromatography: Medicinal Plants

    Science.gov (United States)

    O'Connell, Mary; Lara, Antonio

    2005-01-01

    The Medicinal Plants of the Southwest summer workshop is an inquiry-based learning approach to increase interest and skills in biomedical research. Working in teams, Hispanic and Native American students discover the chemical and biological basis for the medicinal activity of regional plants used by healers. (Contains 4 tables and 1 figure.)

  8. Analysis on the Factors Influencing the Curative Effect of Chinese Patent Medicine%剖析影响中成药疗效的因素

    Institute of Scientific and Technical Information of China (English)

    陈昌钢

    2015-01-01

    The factors influencing the curative ef ect of Chinese traditional medicines are medicines variety and quality,Chinese herbal medicine quality of germplasm resources,Chinese herbal medicine planting cultivation and recovery processing,Chinese herbal medicine recovery processing,Chinese herbal medicine standardized cultivation,preparation technique,form,materials and making preparation, Chinese medicine compatibility between preparations.%影响中成药疗效的因素主要有中药材品种及质量、中药材种质资源质量、中药材种植栽培与采收加工、中药材采收加工、中药材规范化种植、炮制技术、剂型、辅料及制备工艺、中药成方制剂之间的配伍。

  9. [Plant hydroponics and its application prospect in medicinal plants study].

    Science.gov (United States)

    Zeng, Yan; Guo, Lan-Ping; Huang, Lu-Qi; Sun, Yu-Zhang

    2007-03-01

    This article introduced the theorem and method of hydroponics. Some examples of studies in agriculture and forestry were presented, the effects of elements, environmental stress and hormones on physiology of medicinal plants by using hydroponics were analyzed. It also introduced the feasibility and advantage of hydroponics in intermediate propagation and allelopathy of medicinal plant. And finally it made the conclusion that the way of hydroponics would be widely used in medicinal plant study.

  10. Structure analysis of active components of traditional Chinese medicines

    DEFF Research Database (Denmark)

    Zhang, Wei; Sun, Qinglei; Liu, Jianhua

    2013-01-01

    Traditional Chinese Medicines (TCMs) have been widely used for healing of different health problems for thousands of years. They have been used as therapeutic, complementary and alternative medicines. TCMs usually consist of dozens to hundreds of various compounds, which are extracted from raw...

  11. [Research progress of Chinese herbal medicine raw materials in cosmetics].

    Science.gov (United States)

    Xie, Yan-jun; Kong, Wei-jun; Yang, Mei-hua; Yang, Shi-hai

    2015-10-01

    Advocating green, nature, environmental protection, safety and the pursuit of efficacy are the trends of cosmetics in the world. In recent years, more and more Chinese herbal extracts with mild, high safety and small irritation are applied to cosmetics as the natural additives. This has become a new hot spot. The recent application advances of Chinese medicine raw materials in cosmetics are overviewed according to their main functions. This review will provide useful references for the future development and application of Chinese medicinal herbs cosmetics. PMID:27062803

  12. [Research progress of Chinese herbal medicine raw materials in cosmetics].

    Science.gov (United States)

    Xie, Yan-jun; Kong, Wei-jun; Yang, Mei-hua; Yang, Shi-hai

    2015-10-01

    Advocating green, nature, environmental protection, safety and the pursuit of efficacy are the trends of cosmetics in the world. In recent years, more and more Chinese herbal extracts with mild, high safety and small irritation are applied to cosmetics as the natural additives. This has become a new hot spot. The recent application advances of Chinese medicine raw materials in cosmetics are overviewed according to their main functions. This review will provide useful references for the future development and application of Chinese medicinal herbs cosmetics.

  13. Traditional Chinese Medicine Induced Liver Injury.

    Science.gov (United States)

    Teschke, Rolf

    2014-06-01

    Traditional Chinese Medicine (TCM) is popular around the world and encompasses many different practices with particular emphasis on herbal TCM. Using the PubMed database, a literature search was undertaken to assess the extent herbal TCM products exert rare hepatotoxicity. Analysis of reported cases revealed numerous specified herbal TCM products with potential hepatotoxicity. Among these were An Shu Ling, Bai Fang, Bai Xian Pi, Ban Tu Wan, Bo He, Bo Ye Qing Niu Dan, Bofu Tsu Sho San, Boh Gol Zhee, Cang Er Zi, Chai Hu, Chaso, Chi R Yun, Chuan Lian Zi, Ci Wu Jia, Da Chai Hu Tang, Da Huang, Du Huo, Gan Cao, Ge Gen, Ho Shou Wu, Hu Bohe You, Hu Zhang, Huang Qin, Huang Yao Zi, Hwang Geun Cho, Ji Gu Cao, Ji Ji, Ji Xue Cao, Jiguja, Jin Bu Huan, Jue Ming Zi, Kamishoyosan, Kudzu, Lei Gong Teng, Long Dan Xie Gan Tang, Lu Cha, Ma Huang, Mao Guo Tian Jie Cai, Onshido, Polygonum multiflorum, Qian Li Guang, Ren Shen, Sairei To, Shan Chi, Shen Min, Shi Can, Shi Liu Pi, Shou Wu Pian, Tian Hua Fen, White flood, Wu Bei Zi, Xi Shu, Xiao Chai Hu Tang, Yin Chen Hao, Zexie, Zhen Chu Cao, and various unclassified Chinese herbal mixtures. Causality was firmly established for a number of herbal TCM products by a positive reexposure test result, the liver specific scale of CIOMS (Council for International Organizations of Medical Sciences), or both. Otherwise, the quality of case data was mixed, especially regarding analysis of the herb ingredients because of adulteration with synthetic drugs, contamination with heavy metals, and misidentification. In addition, non-herbal TCM elements derived from Agaricus blazei, Agkistrodon, Antelope, Bombyx, Carp, Fish gallbladder, Phellinus, Scolopendra, Scorpio, and Zaocys are also known or potential hepatotoxins. For some patients, the clinical course was severe, with risks for acute liver failure, liver transplantation requirement, and lethality. In conclusion, the use of few herbal TCM products may rarely be associated with hepatotoxicity in some

  14. MYCOPOPULATION OF MEDICINAL PLANTS IN CROATIA

    Directory of Open Access Journals (Sweden)

    Karolina Vrandečić

    2011-12-01

    Full Text Available There has not been a systematic research of medicinal plants mycoflora in Croatia. This paper aims to present the results of preliminary research of mycopopulation of 14 species of medicinal plants. Total of 393 plant parts has been examined and 10 genera of fungi were isolated: Penicillium, Aspergillus, Sordaria, Phoma, Cladosporium, Rhizopus, Stemphillium, Fusarium, Phomopsis and one unidentified genus. Penicillium sp. (from 11 of 14 plant species was isolated from the majority of samples. The plants fungi were isolated from did not show any macroscopically visible symptoms of infection, except plant parts of Lavandula x intermedia and Foeniculum vulgare, from which Phomopsis sp. and Fusarium sp. were isolated

  15. Medicinal plants: production and biochemical characterization

    International Nuclear Information System (INIS)

    Recent advances in the area of biotechnology offer some possibility for the development of new technologies for the conservation, characterization and mass production of medicinal plant species, (i.e. in vitro cell culture techniques for the mass production of sterile, consistent, standardized medicinal plant materials). This paper discussed the following subjects - plant tissue culture, de novo shoot organogenesis, de novo root organogenesis, somatic embryogenesis, large scale propagation in bioreactors and discovery of unique biomolecules

  16. Intercellular communication, NO and the biology of Chinese medicine

    Directory of Open Access Journals (Sweden)

    Ralt Dina

    2005-05-01

    Full Text Available Abstract New multiple categories of health disciplines have become popular in the west and integration between the medicinal approaches has become essential. The hypothesis presented here suggests a novel integrative view that combines Western biochemistry with the Chinese medicinal concept of qi. The core for this hypothesis is that transmission of qi along the meridians is based on informational molecules that travel via an intercellular communication system. Acupuncture at specific points enhances the flow of the signaling molecules through this communication system. Nitric oxide is suggested as a prime candidate for such a signaling molecule in the meridian system. The biochemistry of nitric oxide can shed light on the biology underlying Chinese medicine while Chinese medicinal data can provide a clue to the sought after framework for nitric oxide.

  17. Traditional Chinese and Thai medicine in a comparative perspective.

    Science.gov (United States)

    He, Ke

    2015-12-01

    The work presented in this paper compares traditional Chinese medicine and traditional Thai medicine, expounding on origins, academic thinking, theoretical system, diagnostic method and modern development. Based on a secondary analysis of available literature, the paper concentrates on two crucial historical developments: (1) the response to, and consequences of, the impact of the Western medicine; and (2) the revival of traditional medicine in these two countries and its prospects. From a comparative perspective, the analysis has led to the conclusion that the rise and fall of traditional medicine is an issue closely related with social and political issues; and the development of traditional medicines requires national policy and financial support from governments, human resource development, the improvement of service quality, and the dissemination of traditional medicine knowledge to the public. In addition, this paper also suggests deepening exchanges and cooperation between China and Thailand, strengthening cooperation between traditional medicine and medical tourism. PMID:26645523

  18. Study designs of randomized controlled trials not based on Chinese medicine theory are improper

    Directory of Open Access Journals (Sweden)

    Jiao Yan

    2009-02-01

    Full Text Available Abstract Current biomedical research methods to evaluate the efficacy of Chinese medicine interventions are often conceptually incompatible with the theory and clinical practice of Chinese medicine. In this commentary, we (1 highlight the theory and principles underlying Chinese medicine clinical practice; (2 use ginseng as an example to describe clinical indications in Chinese medicine; (3 propose a framework guided by Chinese medicine theory for the evaluation of study designs in Chinese medicine research; and (4 evaluate 19 randomized, double-blind, placebo-controlled trials of ginseng. Our analysis indicates that all 19 trials with both positive and negative results confirm the specific effects of ginseng indicated by Chinese medicine theory. Study designs guided by Chinese medicine theory are necessary to validate and improve future randomized controlled clinical trials in Chinese medicine.

  19. Contrast between Western Medicine and Traditonal Chinese Medicine on their application

    Institute of Scientific and Technical Information of China (English)

    管隽

    2011-01-01

    It appears that integrating traditional Chinese medicine with western medicine could be of benefit to solve medical problems or improve therapeutic effects.It is concluded that western medicine is more appropriate in treating some diseases which are acute,with a explicit cause,and single-system diseases while traditional Chinese medicine treatment can provide better results in treating some diseases especially which are chronic,without clear cause,and multi-system diseases.It seems possible that this discussion will highlight some diseases which need to be considered seriously to select more effective and reasonable treatments.

  20. Medicinal plants with hepatoprotective activity in Iranian folk medicine

    Institute of Scientific and Technical Information of China (English)

    Majid; Asadi-Samani; Najme; Kafash-Farkhad; Nafiseh; Azimi; Ali; Fasihi; Ebrahim; Alinia-Ahandani; Mahmoud; Rafieian-Kopaei

    2015-01-01

    There are a number of medicinal combinations in the Iranian traditional medicine which are commonly used as tonic for liver.In this review,we have introduced some medicinal plants that are used mainly for the treatment of liver disorders in Iranian folk medicine,with focus on their hepatoprotective effects particularly against CCI4 agent.In this study,online databases including Web of Science.PubMed.Scopus,and Science Direct were searched for papers published from January 1970 to December 2013.Search terms consisted of medicinal plants,traditional medicine,folk medicine,hepatoprotective.Iran,liver,therapeutic uses,compounds,antioxidant.CCI4.anti-inflammatory,and antihepatotoxic,hepatitis,alone or in combination.Allium hirtifolium Boiss..Apium graveolens L..Cynara scolyinus.Berberis vulgaris L..,Calendula officinalis,Nigella sativa L..Taraxacum officinale.Tragopogon porrifolius.Prangos ferulacea L..Allium sativum,Marribium vulgare,Ammi majus L..Citrullus lanatus Thunb.Agrimonia eupatoria L.and Primus armeniaca L.are some of the medicinal plants that have been used for the treatment of liver disorders in Iranian folk medicine.Out of several leads obtained from plants containing potential hepatoprotective agents,silymarin,P-sitosterol,betalain,neoandrographolide.phyllanthin.andrographolide.curcumin.picroside.hypophyllanlhin.kutkoside,and glycyrrhizin have been demonstrated to have potent hepatoprotective properties.Despite encouraging data on possibility of new discoveries in the near future,the evidence on treating viral hepatitis or other chronic liver diseases by herbal medications is not adequate.

  1. Multi-disciplinary Research in Traditional Chinese Medicine--An Exploration

    Institute of Scientific and Technical Information of China (English)

    Mo Feizhi

    2005-01-01

    This paper discusses the present state of Traditional Chinese Medicine being divided into three leading lines of thought, namely, the Clinical line,the Integration of Western and Chinese Medicine line and the Development of Traditional Chinese Medicine line. It also describes the position of Traditional Chinese Medicine being a medical science rich in philosophy and wisdom and a culture centred upon medical science and technology. It outlines the basic characteristic of Traditional Chinese pointed out various flaws in methodology in Integration of Western and Chinese Medicine research. It also stresses that in order to make fruitful progress in the development of Traditional Chinese Medicine,multi-discipline research in Traditional Chinese Medicine should be made on a thoroughly understanding of the basic methodology of Traditional Chinese Medicine and follow its established principles.

  2. Globalization of Traditional Chinese Medicinal products And New Regulatory Structures in the European Union

    Institute of Scientific and Technical Information of China (English)

    Emiel Van Galen; Burt Kroes

    2009-01-01

    @@ Traditional Chinese Medicine (TCM) , Registration, EU pharmaceutical legislation, Traditional Herbal Medicinal Products, tHMP, quality, safety, efficacy, traditional use, EMEA, European Medicines Agency, European Pharmacopoeia, Herbal Medicinal Products Committee, HMPC, Community Monographs, Commu-nity List.

  3. Ayurveda and Traditional Chinese Medicine: A Comparative Overview

    Directory of Open Access Journals (Sweden)

    Bhushan Patwardhan

    2005-01-01

    Full Text Available Ayurveda, the traditional Indian medicine (TIM and traditional Chinese medicine (TCM remain the most ancient yet living traditions. There has been increased global interest in traditional medicine. Efforts to monitor and regulate herbal drugs and traditional medicine are underway. China has been successful in promoting its therapies with more research and science-based approach, while Ayurveda still needs more extensive scientific research and evidence base. This review gives an overview of basic principles and commonalities of TIM and TCM and discusses key determinants of success, which these great traditions need to address to compete in global markets.

  4. Incorporating pattern identification of Chinese medicine into precision medicine: An integrative model for individualized medicine.

    Science.gov (United States)

    Li, Jin-gen; Xu, Hao

    2015-11-01

    On 20 January, 2015, U.S. President Obama announced an ambitious plan called "Precision Medicine (PM) Initiative", aiming to deliver genetics-based medical treatments. PM has shown a promising prospect by tailoring disease treatments and preventions to individuals. However, a predominantly genetics-based method restricts its benefit and applicability in most chronic and complex diseases. Pattern identification (PI) is one of the representative characteristics of Chinese medicine implying the concept of holism and individualized treatment. It is another classification method taking environmental, psychosocial and other individual factors into account. Integrating PI with disease diagnosis of Western medicine will provide a strong complement to genetics-based PM, thus establish an integrative model for individualized medicine. PI provides new perspectives for PM, not only in clinical practice, but also in new drug development and clinical trial design. It is for sure that the integrative approach will ultimately lead to a safer, more convenient and effective patient-centered healthcare and most patients will benefit in the era of PM.

  5. Study on Analgesic Effect of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    YU Shan; XU Ling; WEI Pin-kang; QIN Zhi-feng; LI Jun; PENG Hai-dong

    2008-01-01

    Chinese medicine has been used in treating pain for a long time.Much progress has been made in studies on the mechanism of the analgesic effect of Chinese medicine in animal experiments.It is found that the analgesic action may be related to the following actions:(1)Reducing the secretion of peripheral algogenic substances and inducing the secretion of pain-sensitive substances;(2)Alleviating the accumulation of local algogenic substances;(3)Increasing the release of endogenous analgesic substances;(4)Regulating c-fos gene and increasing the secretion of such substances in the central newous system,etc.In this paper,the experimental methods and analgesic effect of Chinese medicines are reviewed.

  6. Progress of Research on Organic Fibrosis with Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    Qing-Lan Wang; Xiao-Ning Wang; Ping Liu

    2016-01-01

    Fibrosis is the remodeling and repair processes of chronic injuries. There are few effective therapies. Chinese medicine formula, the main pattern of traditional Chinese medicine (TCM) in clinic, applies a multi-component, multi-target and complicated approach in the treatment of diseases, and certainly shows good comprehensive therapeutic effects on fibrosis. In this review, the clinical study, effects and mechanism of action of Fuzheng Huayu recipe in the treatment of liver, pulmonary, and renal fibrosis was analyzed and evaluated. Meanwhile, based on the understanding of TCM pathogenesis for liver cirrhosis, this review will also briefly introduce the research of different classical Chinese medicine formulae with various functions in the treatment of experimental liver fibrosis induced by different methods, including comparing the efficacy, analyzing the action characteristics and mechanism of effective formulae, exploring pathological and biological basis of TCM diagnostic and therapeutic pattern, which will contribute to the research of TCM in the treatment of organ fibrosis.

  7. Antimicrobial activity of amazonian medicinal plants

    OpenAIRE

    Oliveira, Amanda A; Segovia, Jorge FO; Sousa, Vespasiano YK; Mata, Elida CG; Gonçalves, Magda CA; Bezerra, Roberto M; Junior, Paulo OM; Kanzaki, Luís IB

    2013-01-01

    Objectives The aqueous extracts of currently utilized Amazonian medicinal plants were assayed in vitro searching for antimicrobial activity against human and animal pathogenic microorganisms. Methods Medium resuspended lyophilized aqueous extracts of different organs of Amazonian medicinal plants were assayed by in vitro screening for antimicrobial activity. ATCC and standardized microorganisms obtained from Oswaldo Cruz Foundation/Brazil were individually and homogeneously grown in agar plat...

  8. Medicinal Plants Database and Three Dimensional Structure of the Chemical Compounds from Medicinal Plants in Indonesia

    OpenAIRE

    Arry Yanuar; Abdul Mun'im; Akma Bertha Aprima Lagho; Rezi Riadhi Syahdi; Marjuqi Rahmat; Heru Suhartanto

    2011-01-01

    During this era of new drug designing, medicinal plants had become a very interesting object of further research. Pharmacology screening of active compound of medicinal plants would be time consuming and costly. Molecular docking is one of the in silico method which is more efficient compare to in vitro or in vivo method for its capability of finding the active compound in medicinal plants. In this method, three-dimensional structure becomes very important in the molecular docking methods, so...

  9. [Study on Chinese Acup-Mox Medicine by YAO Tianmin].

    Science.gov (United States)

    Li, Jianrong; Huang, Longxiang; Du, Guangzhong; Gang, Weijuan

    2015-06-01

    The characteristics and academic thoughts of Chinese Acup-Mox Medicine written by YAO Tianmin during the Republic of China was studied and analyzed in this paper. The academic thoughts of this book were confluence of Chinese and western knowledge, respecting for classics culture but not stubborn, using western science and medicine without worshiping it. The main characteristics were the scientific meridian-acupoint theory, extensive acupoint selection, "qie" method of acupuncture, high recommendation on medicated thread and ironing moxibustion, reinforcing and reducing based on the meridian direction in infantile massage, using acupuncture and cream formula for surgical treatment, and creating his own acupuncture codes.

  10. GAP - A Milestone in Traditional Chinese Medicine Production

    Institute of Scientific and Technical Information of China (English)

    MENGJIE; YUJIE

    2004-01-01

    IT is clear that in order for TCM (Traditional Chinese Medicine) production to meet world standards and enter the international market, herb plantation in China must be standardized. In late September 2003, the US FDA(Food and Drug Administration)held a seminar on the standardization of TCM development and quality control. It reached the conclusion that as long as the Chinese medicine production process meets GAP (Good Agricultural Practice,meaning standardized herbal material plantation), GLP (Good Laboratory Practice, meaning standardized experimental research)and GMP (Good Manufacturing Practice, meaning standardized extraction and preparation technology) standards, TCM products merit certification.

  11. Spectral Analysis of Chinese Medicinal Herbs Based on Delayed Luminescence

    Directory of Open Access Journals (Sweden)

    Jingxiang Pang

    2016-01-01

    Full Text Available Traditional Chinese medicine (TCM plays a critical role in healthcare; however, it lacks scientific evidence to support the multidimensional therapeutic effects. These effects are based on experience, and, to date, there is no advanced tool to evaluate these experience based effects. In the current study, Chinese herbal materials classified with different cold and heat therapeutic properties, based on Chinese medicine principles, were investigated using spectral distribution, as well as the decay probability distribution based on delayed luminescence (DL. A detection system based on ultraweak biophoton emission was developed to determine the DL decay kinetics of the cold and heat properties of Chinese herbal materials. We constructed a mathematical model to fit the experimental data and characterize the properties of Chinese medicinal herbs with different parameters. The results demonstrated that this method has good reproducibility. Moreover, there is a significant difference (p<0.05 in the spectral distribution and the decay probability distribution of Chinese herbal materials with cold and heat properties. This approach takes advantage of the comprehensive nature of DL compared with more reductionist approaches and is more consistent with TCM principles, in which the core comprises holistic views.

  12. Tianjin Press of Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    <正>Chinese Traditional and Herbal Drugs The journal started publication monthly since January 1970, is an academic and technical journal sponsored by Chinese Pharmaceutical Association and Tianjin Institute of Pharmaceutical Research. The journal which has a long history over 40 years offers the columns of research papers, brief reports, reviews, dissertation, and special treatises to report the recent achievements of the basic study, production, quality

  13. Medicinal plants with anti-inflammatory activities.

    Science.gov (United States)

    Maione, Francesco; Russo, Rosa; Khan, Haroon; Mascolo, Nicola

    2016-06-01

    Medicinal plants have been the main remedy to treat various ailments for a long time and nowadays, many drugs have been developed from traditional medicine. This paper reviews some medicinal plants and their main constituents which possess anti-inflammatory activities useful for curing joint inflammation, inflammatory skin disorders, cardiovascular inflammation and other inflammatory diseases. Here, we provide a brief overview of quick and easy reading on the role of medicinal plants and their main constituents in these inflammatory diseases. We hope that this overview will shed some light on the function of these natural anti-inflammatory compounds and attract the interest of investigators aiming at the design of novel therapeutic approaches for the treatment of various inflammatory conditions.

  14. 半仿生技术在中药黄酮类成分提取中的应用进展%Progress in Semi-Bionic Extraction of Flavonoids from Traditional Chinese Medicinal Plants

    Institute of Scientific and Technical Information of China (English)

    杨姜德; 刘可越; 何明; 裘佳龄

    2015-01-01

    综述了黄酮类化合物的半仿生提取法。中草药有关半仿生提取方法包括半仿生提取法,半仿生提法醇提取法、微波辅助半仿生提取法、超声波辅助半仿生提取法、酶辅助半仿生提取法等。黄酮类化合物是一类重要活性物质,具有特殊的保健功能。本文旨在为黄酮类化合物的提取研究、开发、应用提供一定的参考。%ABSTRACT:This paper reviews the semi-bionic extraction of flavonoids.The semi-bionic extrac-tion methods related to traditional Chinese medicinal plants include semi-bionic extraction,semi-bionic alcohol extraction,microwave-assisted semi-bionic extraction,ultrasonic-assisted semi-bion-ic extraction,enzyme-assisted semi-bionic extraction,etc.Flavonoids are a class of important ac-tive substances with special health functions.This paper aims to provide a reference for the ex-traction,development and application of flavonoids.

  15. [Innovation guidelines and strategies for pharmaceutical engineering of Chinese medicine and their industrial translation].

    Science.gov (United States)

    Cheng, Yi-Yu; Qu, Hai-Bin; Zhang, Bo-Li

    2013-01-01

    This paper briefly analyzes the bottlenecks and major technical requirements for pharmaceutical industry of Chinese medicine, providing current status of pharmaceutical engineering of Chinese medicine. The innovation directions and strategies of the pharmaceutical engineering for manufacturing Chinese medicine are proposed along with the framework of their core technology. As a consequence, the development of the third-generation pharmaceutical technology for Chinese medicine, featured as "precision, digital and intelligent", is recommended. The prospects of the pharmaceutical technology are also forecasted.

  16. [Industry of traditional Chinese patent medicine science and technology development and review].

    Science.gov (United States)

    Lu, Jianwei; Wang, Fang; Yan, Dongmei; Luo, Yun; Yang, Ming

    2012-01-01

    "Fifteen" since, our country Chinese traditional medicine industry science and technology has made remarkable achievements. In this paper, the development of science and technology policy, Chinese medicine industry, platform construction and other aspects were analyzed, showing 10 years of Chinese traditional medicine industry development of science and technology innovation achievement and development, and on the current development of traditional Chinese medicine industry facing the main tasks and guarantee measures are analyzed. PMID:22741452

  17. [Microscopic and polariscopic characteristics of 30 medicinal plants of Polygonum].

    Science.gov (United States)

    Wang, Ying-Yu; Zhang, Chao-Feng; Zhang, Mian

    2012-09-01

    Polygonum L. s. str., belonging to Polygonaceae family, is a big genus with abundant medicinal plants. More than 10 plants are specified in Chinese Pharmacopoeia and many local medicinal standards and over 50 species are used as folk medicines. Owing to the similar morphologies and very small flowers and fruits, they are uneasily identified and often confused with each other and misused clinically. In order to provide a basis for identification of Polygonum s. str. plants, a histological study on stems and leaves of 30 species from Polygonum was undertaken by a routine/polarized light microscopy for the first time. The results showed that: (1) the transverse sections of stems of Polygonum are relatively similar, sclerenchyma such as xylem and fibres with strong polarization effects; (2) the surface views of leaves of Polygonum are distinguishable on distributions and types of stomata, with or without attachments (such as glandular hairs/scales or non-glandular hairs) and the polariscopic features of epidermal cell walls, stomata and cell contents. Observed under polarized light, it was found for the first time that stomata on leaf surface of some plants have a Maltese-cross effect with the arms of the cross intersecting at the stomatal opening. As a result, a key combining the microscopic and polariscopic characteristics of the stems as well as leaves was provided for identifying the 30 medicinal plants of Polygonum. The polarized light microscopic method was proven to be one of the quick, simple and effective techniques for the identification of medicinal plants and botanic crude materials.

  18. 茜草等25种中药材对5种植物病原真菌的抑制活性%Antifungal activities of the extracts from 25 traditional Chinese medicines against 5 plant pathogenic fungi

    Institute of Scientific and Technical Information of China (English)

    牛赡光; 杜丰玉

    2015-01-01

    The antifungal activities of the extracts from 25 traditional Chinese medicines against 5 plant pathogenic fungi,Valsa mali ,Botryosphaeria dothidea ,Fusarium oxysporum f.sp.vasinfectum ,Colletotrichum gloeospori-oides ,and Alternaria brassicae ,were studied using the growth rate method.The methanol extracts of most of 25 traditional Chinese medicines showed antifungal activities against at least one plant pathogenic fungi.The inhibi-tion rates of extracts from Anemarrhena asphodeloides ,Artemisia annua ,Asarum heterotropoides var.mandshu-ricum ,and Dictamnus dasycarpus were more than 75% against 3 plant pathogenic fungi.The extracts from Rubia cordifolia and Curcuma longa also showed the significant inhibition rates of more than 80% against 4 plant patho-genic fungi at the concentration of 5 mg/mL.The methanol extract of R .cordifolia was further isolated to obtain four subfractions using different polar solvents.The bioactive screening exhibited that the subfraction of water-saturated n-butanol showed a better antifungal activity than those of petroleum ether and ethyl acetate,which in-dicated that the bioactive compounds of R .cordifolia should have the medium and large polarities.%以苹果腐烂病菌、苹果轮纹病菌、棉花枯萎病菌、柑橘炭疽病菌与白菜黑斑病菌为供试菌,采用生长速率法测定25种中药材甲醇粗提物的抑菌活性。结果表明,在浓度为5.0 mg/mL 时,大部分中药材的甲醇粗提物对至少一种植物病原真菌都表现出不同程度的抑制活性,其中知母、青蒿、细辛与白鲜皮对3种供试植物病原菌的抑制率大于75%,而茜草与姜黄对4种供试植物病原菌的抑制率均在80%以上,具有广泛的抑菌谱。进一步采用系统溶剂法得到的茜草不同溶剂萃取物中,水饱和正丁醇相抑菌活性明显优于石油醚及乙酸乙酯相,表明茜草抑菌活性成分主要为中等及大极性化合物。

  19. Traditional use of medicinal plants by elderly

    Directory of Open Access Journals (Sweden)

    Alexandre Rocha Alves Pereira

    2016-01-01

    Full Text Available Objective: identify the traditional use of medicinal plants by the elderly. Methods: exploratory and descriptive study conducted in the Intermunicipal Consortium on Health. Three hundred and fifty-one questionnaires were applied to the elderly to survey socio-demographic information and issues related to plants. Results: the use of plants was reported by 78.4% of the elderly, and these were collected in backyards. The most often cited plants were mint, boldo, fennel, lemongrass and chamomile. Regarding the reason for use, 33.3% participants said that “it’s not harmful to health”, 61.8% usually indicate the use to other people. Most elderly make use of plants in a safe manner, and these are present in the daily lives of these people as a therapeutic method. Conclusion: the elderly make use of medicinal plants as an important therapeutic resource.

  20. Traditional use of medicinal plants by elderly

    Directory of Open Access Journals (Sweden)

    Alexandre Rocha Alves Pereira

    2016-06-01

    Full Text Available Objective: identify the traditional use of medicinal plants by the elderly. Methods: exploratory and descriptive study conducted in the Intermunicipal Consortium on Health. Three hundred and fifty-one questionnaires were applied to the elderly to survey socio-demographic information and issues related to plants. Results: the use of plants was reported by 78.4% of the elderly, and these were collected in backyards. The most often cited plants were mint, boldo, fennel, lemongrass and chamomile. Regarding the reason for use, 33.3% participants said that “it’s not harmful to health”, 61.8% usually indicate the use to other people. Most elderly make use of plants in a safe manner, and these are present in the daily lives of these people as a therapeutic method. Conclusion: the elderly make use of medicinal plants as an important therapeutic resource.

  1. Spectral Analysis of Chinese Medicinal Herbs Based on Delayed Luminescence.

    Science.gov (United States)

    Pang, Jingxiang; Zhu, Xiaoyan; Liu, Yanli; Fu, Jialei; Zhao, Xiaolei; Yang, Meina; van Wijk, Eduard; Wang, Mei; Nie, Xiaoyan; Han, Jinxiang

    2016-01-01

    Traditional Chinese medicine (TCM) plays a critical role in healthcare; however, it lacks scientific evidence to support the multidimensional therapeutic effects. These effects are based on experience, and, to date, there is no advanced tool to evaluate these experience based effects. In the current study, Chinese herbal materials classified with different cold and heat therapeutic properties, based on Chinese medicine principles, were investigated using spectral distribution, as well as the decay probability distribution based on delayed luminescence (DL). A detection system based on ultraweak biophoton emission was developed to determine the DL decay kinetics of the cold and heat properties of Chinese herbal materials. We constructed a mathematical model to fit the experimental data and characterize the properties of Chinese medicinal herbs with different parameters. The results demonstrated that this method has good reproducibility. Moreover, there is a significant difference (p cold and heat properties. This approach takes advantage of the comprehensive nature of DL compared with more reductionist approaches and is more consistent with TCM principles, in which the core comprises holistic views. PMID:27478482

  2. The biosynthetic products of chinese insect medicine, Aspongopus chinensis

    Science.gov (United States)

    Luo, Xiao-Hong; Wang, Xiao-Zheng; Jiang, Hai-Long; Yang, Jun-Li; Crews, Phillip; Valeriote, Frederick A.; Wu, Quan-Xiang

    2012-01-01

    A new oxazole (1) was obtained from chinese insect medicine Aspongopus chinensis, along with three known N-acetyldopamine derivatives (2–4). Their structures were determined on the basis of NMR and ESI-MS analyses. The possible biosynthetic pathways of the isolated compounds are discussed. Cytotoxicities of those compounds against 10 selected cancer cells were measured in vitro. PMID:22430116

  3. Effects of Traditional Chinese Medicine on Congestive Heart Failure

    Institute of Scientific and Technical Information of China (English)

    任海玲; 李海芸; 江时森

    2002-01-01

    Congestive heart failure (CHF) belongs to the category of "palpitation", "chest pain", "retention of phlegm and fluid" etc. in traditional Chinese medicine (TCM). The medical books of past generations recorded a lot of important prescriptions to treat above-mentioned symptoms. This article briefly summarized certain TCM prescriptions on pharmacological actions and therapeutic effects of CHF.

  4. Strategies for the Development of Chinese Medicine Experience of Hong Kong Special Administrative Region

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    @@While practitioners of western medicine are the main health care providers in Hong Kong, Chinese medicine plays a significant role in the health care system in Hong Kong. Its popularity of use and its strength in contributing to the health of the community provides the drive for its development. The following summarises the role played by Chinese medicine in the health care system and our strategies in developing Chinese medicine in a western medicine dominant health care system.

  5. Cinnamon: A Multifaceted Medicinal Plant

    OpenAIRE

    Pasupuleti Visweswara Rao; Siew Hua Gan

    2014-01-01

    Cinnamon (Cinnamomum zeylanicum, and Cinnamon cassia), the eternal tree of tropical medicine, belongs to the Lauraceae family. Cinnamon is one of the most important spices used daily by people all over the world. Cinnamon primarily contains vital oils and other derivatives, such as cinnamaldehyde, cinnamic acid, and cinnamate. In addition to being an antioxidant, anti-inflammatory, antidiabetic, antimicrobial, anticancer, lipid-lowering, and cardiovascular-disease-lowering compound, cinnamon...

  6. [Study of changes in Chinese herbal medicine distribution channel].

    Science.gov (United States)

    Lv, Hua; Yang, Guang; Huang, Lu-Qi

    2014-07-01

    Distribution channel of Chinese herbal medicines has been changing. From Han to Ming Dynasty, Chinese herbal medicine were mainly trafficked to urban by dealers or farmers; From the Ming Dynasty to the foundation of new China, distribution channels are primarily intermediated with township "bazaar" and national distribution center with fixed place and regularly trading hours. In the planned economy period, the state-owned herbal medicine company was the sole medium with monopoly nature. From the mid1980s to the end of last century, planned economy and market economy have been co-existing. Stepping into 21st century, producing area highlighted in the distribution channels. Presence or absence and rise or fall of different types of distribution market went throughout the changing process of distribution channels, which became an important clue. Changes were motivated by economical consideration of channel subject, which originated from commodity characteristic and social environment changes. PMID:25272514

  7. Chemical composition of selected Saudi medicinal plants

    Directory of Open Access Journals (Sweden)

    Ihsanullah Daur

    2015-05-01

    Full Text Available Medicinal plants are important in traditional medicine and modern pharmaceutical drugs; therefore, the interest in the analysis of their chemical composition is increasing. In this study, selected medicinal plants including Achillea fragrantissima (Forssk Sch., Amaranthus viridis L., Asteriscus graveolens (Forssk. Less., Chenopodium album L., and Conyza bonariensis (L. Cronquist were collected from the rangeland of western regions (Bahra and Hada areas of Saudi Arabia to study their chemical composition. Eight minerals (Mg, Ca, Cr, Mn, Fe, Co, Cu, and Zn, total phenolic contents, antioxidant activity, and free-radical scavenging ability were examined in order to evaluate the medicinal potential of these plants. All the plants were found to be rich sources of minerals and antioxidants, although there were significant differences (p < 0.05 in their chemical composition, which may provide a rationale for generating custom extracts from specific plants depending on the application. The findings of this study will thus facilitate herbalists in their efforts to incorporate these plants into various formulations based on their chemical composition.

  8. ANTIVIRAL POTENTIAL OF MEDICINAL PLANTS: AN OVERVIEW

    Directory of Open Access Journals (Sweden)

    Ruwali Pushpa

    2013-06-01

    Full Text Available The term ‘Antiviral agents’ has been defined in very broad terms as substances other than a virus or virus containing vaccine or specific antibody which can produce either a protective or therapeutic effect to the clear detectable advantage of the virus infected host. The herbal medicine has a long traditional use and the major advantage over other medicines is their wide therapeutic window with rare side effects. There are some disadvantages of synthetic drugs like narrow therapeutic window and more importantly the various adverse side effects which occur quite frequently. Due to these disadvantages and other limitations, there is an increasing trend in the field of research for discovering new and noble drugs based on various herbal formulations. This review attempts to address the importance of developing therapeutic herbal formulations from various medicinal plants using the knowledge based on traditional system of medicines, the Ayurveda. Although natural products have been used by civilization since ancient times, only in recent decades has there been growing research into alternative therapies and the therapeutics use of natural products, especially those derived from plants. Plants synthesize and preserve a variety of biochemical products, many of which are extractable and used for various scientific investigations. Therefore, medicinal plants proved to be a major resort for the treatment of diseases and sicknesses by traditional healers in many societies.

  9. [Changes and establishment of the principle of "Unity of traditional Chinese medicine and western medicine"].

    Science.gov (United States)

    Li, Jian

    2014-11-01

    "Unity of traditional Chinese and western medicine" was one of the three major health work principles at the early founding of the People's Republic of China. It was not only a choice of political strategy in line with the lack of contemporary health-care resources, but also a part of the revolutionary heritage for more than 20 years in the process of the Chinese Communist Party from the preliminary "application of both traditional and western medicine" to the making of the principles of both "cooperation of traditional Chinese and western medicine" and "unity of traditional Chinese and western medicine". All this was closely related to the concrete environment of the Chinese health work of various stages of Yan'an period with strong revolutionary atmosphere and was not the professional demand of the health workers, rather, this principle set up in 1950 was the result of the careful consideration of Mao Zedong and an adjustment guided under the revolutionary framework of Neo-democracy set up under the guidance of the Common Principle which was a bettered adaptation to the contemporary national condition.

  10. The use of Chinese herbal drugs in Islamic medicine

    Institute of Scientific and Technical Information of China (English)

    Mojtaba Heyadri; Mohammad Hashem Hashempur; Mohammad Hosein Ayati; Detlev Quintern; Majid Nimrouzi; Seyed Hamdollah Mosavat

    2015-01-01

    This paper investigates some of the ways that Chinese medicine has been transferred to the Western world and to Islamic territories. During the Golden Age of Islam (8th to 13th century CE), the herbal drug trade promoted significant commercial and scientific exchange between China and the Muslim world. Chinese herbal drugs have been described by medieval Muslim medical scholars such as Tabari (870 CE), Rhazes (925 CE), Haly Abbas (982 CE), Avicenna (1037 CE) and Jurjani (1137 CE). The term al-sin (the Arabic word for China) is used 46 times in Avicenna’s Canon of Medicine in reference to herbal drugs imported from China. Cinnamon (dar sini; “Chinese herb”), wild ginger (asaron), rhubarb (rivand-e sini), nutmeg (basbasa), incense tree wood (ood), cubeb (kababe) and sandalwood (sandal) were the most frequently mentioned Chinese herbs in Islamic medical books. There are also multiple similarities between the clinical uses of these herbs in both medical systems. It appears that Chinese herbal drugs were a major component of the exchange of goods and knowledge between China and the Islamic and later to the Western world amid this era.

  11. The use of Chinese herbal drugs in Islamic medicine.

    Science.gov (United States)

    Heyadri, Mojtaba; Hashempur, Mohammad Hashem; Ayati, Mohammad Hosein; Quintern, Detlev; Nimrouzi, Majid; Heyadri, Mojtaba

    2015-11-01

    This paper investigates some of the ways that Chinese medicine has been transferred to the Western world and to Islamic territories. During the Golden Age of Islam (8th to 13th century CE), the herbal drug trade promoted significant commercial and scientific exchange between China and the Muslim world. Chinese herbal drugs have been described by medieval Muslim medical scholars such as Tabari (870 CE), Rhazes (925 CE), Haly Abbas (982 CE), Avicenna (1037 CE) and Jurjani (1137 CE). The term al-sin (the Arabic word for China) is used 46 times in Avicenna's Canon of Medicine in reference to herbal drugs imported from China. Cinnamon (dar sini; "Chinese herb"), wild ginger (asaron), rhubarb (rivand-e sini), nutmeg (basbasa), incense tree wood (ood), cubeb (kababe) and sandalwood (sandal) were the most frequently mentioned Chinese herbs in Islamic medical books. There are also multiple similarities between the clinical uses of these herbs in both medical systems. It appears that Chinese herbal drugs were a major component of the exchange of goods and knowledge between China and the Islamic and later to the Western world amid this era. PMID:26559361

  12. [The motive characteristics and pattern of manifestation of Chinese medicinal herb during the period of "Cultural Revolution"].

    Science.gov (United States)

    Zhang, Wei; Zhang, Rui-xian

    2009-01-01

    During the period of "Cultural Revolution", there started a movement of Chinese medicinal herb throughout the whole country. As a national movement meeting the needs of the time, not only had the guarantee of national policy, but also had the support of finance and the propaganda of People's Daily, PLA Daily and Red Flag Magazine. The movement had all kinds of different manifestations such as cooperative medical care, mobile medical team, research team, three tu (folk recipe, folk healer, folk medicine), four selves (self-planting, self-collection, self-making, self-use), exhibition of Chinese medicinal herb, compiling the handbook of Chinese medicinal herb etc. It had reference values to the current medical care system. PMID:19824359

  13. New exploration and understanding of traditional Chinese medicine.

    Science.gov (United States)

    Xutian, Stevenson; Zhang, Jun; Louise, Wozniak

    2009-01-01

    Traditional Chinese Medicine (TCM), originating from oriental philosophy and culture, has been developing through a series of special research and experiments with meditation, accumulation of experiences, and a complete comprehension of ancient theories and methods. However, compared with Conventional Western Medicine (CWM), the theory of TCM is complicated and not easily accepted by Westerners. It is important to explore TCM by using modern scientific techniques and theories. Utilizing his frontier experience and up-to-date scientific knowledge, Dr. Qian Xuesen has been trying to incorporate some key principles with the comprehensive understanding of TCM and clarify difficult but important concepts and principles. Some examples are the existence of invisible matter; 'Qi' and 'Qi monism'; the Heart representing the 'whole will' of human beings; the water environment functioning as a fundamental condition of life; the human body being united with nature and universe as one; the spirit and physical body always being considered unified and connected with the five viscera, especially with the Heart; and the Chinese herbal formula working with different principles than CWM drugs. These works are important for understanding the essence of TCM, the promoting of the modernization of TCM theories by means of the latest of achievements in scientific developments, establishing the direction for future medicines with TCM characteristics, uniting Chinese and Western medicines, and exploiting a bright future for the health of mankind. PMID:19606504

  14. Advances of Chinese and Western Medicine on Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    Na-na HE

    2015-03-01

    Full Text Available Rheumatoid arthritis (RA is a kind of chronic general immunological disease with primary clinical characteristic being joint synovitis, and no specific treatment has been found at present. In China, its morbidity is in an increasing trend, and also shows a trend of getting younger. RA is complicated in symptoms and chronic disease course, leading to joint ankylosis, deformity and even disability, which seriously threaten patients' psychological and physical health as well as the quality of life (QOL. RA, which belongs to “ Bi” symdrome, is termed as “arthroncus of knee” or “severe and migratory arthralgia” in traditional Chinese medicine (TCM, for which TCM focuses on expelling wind to remove cold, tonifying qi to activate blood and dispelling dampness to smooth collaterals while the western medicines mainly based on the principles of anti-inflammation, analgesia and inhibiting autoimmune response. However, both Chinese and western medicines have certain advantages in treating RA. Therefore, this study primarily reviewed the advances of Chinese and western medicines in RA treatment in the hope of providing theoretical basis for the clinical treatment of RA.

  15. Advances of Chinese and Western Medicine on Rheumatoid Arthritis

    Institute of Scientific and Technical Information of China (English)

    HE Na-na; WU Zhi-sen; XING Zhen-long; ZHANG Zhi-gang; SUN Shi-xuan; LIN Fa-cai

    2015-01-01

    Rheumatoid arthritis (RA) is a kind of chronic general immunological disease with primary clinical characteristic being joint synovitis, and no speciifc treatment has been found at present. In China, its morbidity is in an increasing trend, and also shows a trend of getting younger. RA is complicated in symptoms and chronic disease course, leading to joint ankylosis, deformity and even disability, which seriously threaten patients’ psychological and physical health as well as the quality of life (QOL). RA, which belongs to“Bi”symdrome, is termed as“arthroncus of knee”or“severe and migratory arthralgia”in traditional Chinese medicine (TCM), for which TCM focuses on expelling wind to remove cold, tonifying qi to activate blood and dispelling dampness to smooth collaterals while the western medicines mainly based on the principles of anti-inflammation, analgesia and inhibiting autoimmune response. However, both Chinese and western medicines have certain advantages in treating RA. Therefore, this study primarily reviewed the advances of Chinese and western medicines in RA treatment in the hope of providing theoretical basis for the clinical treatment of RA.

  16. 淫羊藿药用植物种质资源%Study on Germplasm Resources of the Medicinal Plant of Epimedium in Chinese

    Institute of Scientific and Technical Information of China (English)

    何顺志; 徐文芬; 王悦云; 杨相波; 周宁; 贺勇

    2012-01-01

    By field investigation and taxonomy study, germplasm resources of 19 species of Epimedium have been found in Guizhou Province. Of which E. pubescens, E. brevieornu, E. koreanum, E. wushanense and E. sagitta- turn are species of Chinese Pharmacopoeia. E. acuminutum, E. myrianthum, E. coactum and E. leptorrhizum are species of local standards in Guizhou Province. E. borealiguizhouense, E. eoactum and E. dewuense are the unique germplasm resources of Guizhou Province. E. davidii, E. elongatum, E. ecalearatum, E. fangii and E. pauciflo- rum are species of local standards in Siehuan Province.%通过资源调查及分类学研究,我国有淫羊藿药用植物种质资源19种,其中柔毛淫羊藿Epimediumpubescens、淫羊藿Ebrevicornu、朝鲜淫羊藿E.koreanum、巫山淫羊藿Ewushanense、箭叶淫羊藿Esagittatum为中国药典收栽种;粗毛淫羊藿Eacuminutum、天平山淫羊藿Emyrianthum、毡毛淫羊藿Ecoactum、黔岭淫羊藿E.1eptorrhizum为贵州省地方标准收栽种。黔北淫羊藿E.borealiguizhouense、毡毛淫羊藿Ecoactuln、德务淫羊藿Edewuenze为贵州特有种质资源;宝兴淫羊藿Edavidii、川西淫羊藿Eelongatum、无距淫羊藿Eecalcaratum、方氏淫羊藿E.fangii、少花淫羊藿E.pauciflorum为四川特有种质资源。

  17. The efficacy of Chinese medicine for SARS: a review of Chinese publications after the crisis.

    Science.gov (United States)

    Leung, Ping-Chung

    2007-01-01

    During the SARS crisis in China, 40-60% infected patients, at some stages of their treatment, received Chinese medicine treatment on top of the standard modern medicine treatment. This practice was endorsed and encouraged by the Chinese Center for Disease Control and Prevention, and some details of the herbal treatment were recommended. A review of the publications during and after the SARS crisis enabled us to get an objective view of the true value of the adjuvant therapy using Chinese medicinal herbs. Of the 130 articles searched, 90 were of reasonable quality and contained sufficient information for the enlightenment of the situation. These were reviewed. The results revealed positive but inconclusive indications about the efficacy of the combined treatments using Chinese medicine as an adjuvant. Positive effects using adjuvant herbal therapy included better control of fever, quicker clearance of chest infection, lesser consumption of steroids and other symptoms relief. In a few reports, some evidences of immunological boosterings were also found. More caution is required on the allegation about the efficacy of herbal medicine for the treatment or prevention of viral infection affecting the respiratory tract, while more clinical studies are indicated.

  18. TRADITIONAL MEDICINAL PLANTS: ANCIENT AND MODERN APPROACH

    OpenAIRE

    Sharma, S C; Ahmad, S. Aziz

    1992-01-01

    History of medicine and plants dates back to remote past when herbal treatment was the only answer to all kind of ailments. Nowadays, greater emphasis is again being laid to phytotherapy all over the world. Besides, cultivation-cum-setting up herbal gardens are also mooted on hills and plain areas as management of all kinds of diseases is possible through plant drugs sans toxicity.

  19. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    OpenAIRE

    Ming Hong; Ning Wang; Hor Yue Tan; Sai-Wah Tsao; Yibin Feng

    2015-01-01

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of ne...

  20. A Brief on Pain and Its Patterns in Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    MOJTABAVI; Seyed; Javad; 郭长青; 陈幼楠

    2009-01-01

    Pain is the most common symptom in clinics.Therefore,the quality,time course and location of pain are important for the diagnosis and treatment.However,pain is very difficult to define,and it is one of the conditions poorly understood by the medical sciences.In Western medicine pain is often described in terms of a penetrating or tissue-destructive process and/or emotional reactions,but in Chinese medicine the pathogenesis and description of pain are different.It is described based on the theories and pa...

  1. To Set Up a Logistic Regression Prediction Model for Hepatotoxicity of Chinese Herbal Medicines Based on Traditional Chinese Medicine Theory.

    Science.gov (United States)

    Liu, Hongjie; Li, Tianhao; Chen, Lingxiu; Zhan, Sha; Pan, Meilan; Ma, Zhiguo; Li, Chenghua; Zhang, Zhe

    2016-01-01

    Aims. To establish a logistic regression (LR) prediction model for hepatotoxicity of Chinese herbal medicines (HMs) based on traditional Chinese medicine (TCM) theory and to provide a statistical basis for predicting hepatotoxicity of HMs. Methods. The correlations of hepatotoxic and nonhepatotoxic Chinese HMs with four properties, five flavors, and channel tropism were analyzed with chi-square test for two-way unordered categorical data. LR prediction model was established and the accuracy of the prediction by this model was evaluated. Results. The hepatotoxic and nonhepatotoxic Chinese HMs were related with four properties (p 0.05). There were totally 12 variables from four properties and five flavors for the LR. Four variables, warm and neutral of the four properties and pungent and salty of five flavors, were selected to establish the LR prediction model, with the cutoff value being 0.204. Conclusions. Warm and neutral of the four properties and pungent and salty of five flavors were the variables to affect the hepatotoxicity. Based on such results, the established LR prediction model had some predictive power for hepatotoxicity of Chinese HMs.

  2. Reason Analysis and Risk Prevention of Soaring Price of Traditional Chinese Medicinal Materials

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    In recent years,the price of traditional Chinese medicinal materials soars continuously,and the resulting price risk increasingly looms large,which has critically affected midstream and downstream industries and peoples’ demand for drug,and imperiled healthy and orderly development of traditional Chinese medicinal industries.Based on the status quo of continuous skyrocketing price of traditional Chinese medicinal materials at present,we winkle out the root cause of soaring price as follows:the supply and demand lose balance;the production costs hike up;there are other factors responsible for soaring price.This paper further analyses the impact of sharp increase in price of traditional Chinese medicinal materials on all links of industry chain as follows:the medicinal herb growers never benefit from soaring price;the counterfeiters and forgers in midstream industry increase;the gross profit rate of Chinese medicine enterprises declines.In accordance with the risk arising from abnormal fluctuation in price of traditional Chinese medicinal materials,corresponding precautionary measures are put forward as follows:promote the quality of traditional Chinese medicinal materials through management of value chain;curtail the production and management cost of traditional Chinese medicinal materials through management of organization chain;stabilize price of traditional Chinese medicinal materials through management of information chain;reduce transaction cost of traditional Chinese medicinal materials through management of logistics chain.

  3. Promoting the Development of Traditional Chinese Medicine in the New Century

    Institute of Scientific and Technical Information of China (English)

    佘静

    2001-01-01

    @@Reviewing the past, traditional Chinese medicine (TCM) in the 20th century experienced vicissitude. Since the founding the People's Republic of China, especially for the past twenty years, traditional Chinese medicine undertaking, full of vigor and vitality, has made an unprecedented development in China. The legal status and scientific status of traditional Chinese medicine and pharmacology have already been established. The medical system of traditional Chinese medicine, which is composed of traditional Chinese medicine hospitals, ethnic minority medicine hospitals, integration of traditional and western medicine hospitals and comprehensive hospitals, is playing an important role in preventing, treating diseases and enhancing people's health level. The system of production and circulation for traditional Chinese medicine has basically guaranteed the people's demand for Chinese medicine, with the principles of producing medicinal materials as basis, taking Chinese medicine industry as pillar and Chinese medicine as link. Remarkable achievements have been scored in the research of TCM development as well as research of TCM basic theory and clinical treatment. A number of scientific and technological results have been transformed into productive forces. TCM education has formed a rational pattern based on inheriting traditional way of transmission from master to disciple as well as taking the university and college education as the main part. Minority medical science has been further explored and sorted out; the level of medical treatment, teaching and scientific research for ethnic minority medicines has been improved. As the contingent of integrated traditional and western medicine is growing steadily, medical treatment system, scientific research system and teaching system for integrated traditional and western medicine takes shape progressively. International exchange and cooperation on traditional Chinese medicine has been greatly promoted. Various forms of

  4. Commentary: "A systems view on the future of medicine: Inspiration from Chinese medicine?"

    NARCIS (Netherlands)

    Verpoorte, R.; Crommelin, D.; Danhof, M.; Gilissen, L.J.W.J.; Schuitmaker, H.; Greef, de J.; Witkamp, R.F.

    2009-01-01

    Chinese medicine could serve as a source of inspiration for drug development. Using systems biology in combination with reverse pharmacology is a novel way for the discovery of novel biological active compounds and targets as well as for proving the occurrence of synergy and prodrugs. A key factor f

  5. Treatment of Chinese Traditional Medicine Wastewater by Photosynthetic Bacteria

    Institute of Scientific and Technical Information of China (English)

    WANG You-zhi; WANG Feng-jun; BAO Li

    2005-01-01

    The influence factors treating wastewater of Chinese traditional medicine extraction by photosynthetic bacteria are tested and discussed. The results indicate that the method of photosynthetic bacteria can eliminate COD and BCD from wastewater in high efficiency. And it also has high load shock resistance. On the conditions of slight aerobic and semi-darkness, treating wastewater of Chinese traditional medicine extraction, the method has better efficiency to eliminate COD and BOD from the wastewater than those by anaerobic illumination and aerobic darkness treatments. After pretreatment of hydrolytic acidization, the removal rate of COD in the wastewater reached more than 85 %, and that rate of BOD reached more than 90% in the treating system of photosynthetic bacteria. It may be more feasible and advantageous than traditional anaerobic biological process to treat organic wastewater using PSB system.

  6. Molecular Imaging in Traditional Chinese Medicine Therapy for Neurological Diseases

    OpenAIRE

    Zefeng Wang; Haitong Wan; Jinhui Li; Hong Zhang(Department of Physics and Center for Quantum Spacetime (CQUeST), Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul, 121-742 Korea); Mei Tian

    2013-01-01

    With the speeding tendency of aging society, human neurological disorders have posed an ever increasing threat to public health care. Human neurological diseases include ischemic brain injury, Alzheimer's disease, Parkinson's disease, and spinal cord injury, which are induced by impairment or specific degeneration of different types of neurons in central nervous system. Currently, there are no more effective treatments against these diseases. Traditional Chinese medicine (TCM) is focused on, ...

  7. Effects of Traditional Chinese Patent Medicine on Essential Hypertension

    OpenAIRE

    Xiong, Xingjiang; WANG, PENGQIAN; Zhang, Yuqing; Li, Xiaoke

    2015-01-01

    Abstract Traditional Chinese patent medicine (TCPM) is widely used for essential hypertension (EH) in China. However, there is no critically appraised evidence, such as systematic reviews or meta-analyses, regarding the potential benefits and disadvantages of TCPM to justify their clinical use and recommendation. The aim of this review was to systematically evaluate and meta-analyze the effects of TCPM for EH. Seven databases, the Cochrane Library, PubMed, EMBASE, the China National Knowledge...

  8. Antimicrobial properties of Honduran medicinal plants.

    Science.gov (United States)

    Lentz, D L; Clark, A M; Hufford, C D; Meurer-Grimes, B; Passreiter, C M; Cordero, J; Ibrahimi, O; Okunade, A L

    1998-12-01

    Ninety-two plants used in the traditional pharmacopoeia of the Pech and neighboring Mestizo peoples of central Honduras are reported. The results of in vitro antimicrobial screens showed that 19 of the extracts from medicinal plants revealed signs of antifungal activity while 22 demonstrated a measurable inhibitory effect on one or more bacterial cultures. Bioassay-guided fractionation of extracts from Mikania micrantha, Neurolaena lobata and Piper aduncum produced weak to moderately active isolates. The broad spectrum of activity of the extracts helps to explain the widespread use of these plants for wound healing and other applications. PMID:10030730

  9. Biological screening of Brazilian medicinal plants

    Directory of Open Access Journals (Sweden)

    Alves Tânia Maria de Almeida

    2000-01-01

    Full Text Available In this study, we screened sixty medicinal plant species from the Brazilian savanna ("cerrado" that could contain useful compounds for the control of tropical diseases. The plant selection was based on existing ethnobotanic information and interviews with local healers. Plant extracts were screened for: (a molluscicidal activity against Biomphalaria glabrata, (b toxicity to brine shrimp (Artemia salina L., (c antifungal activity in the bioautographic assay with Cladosporium sphaerospermum and (d antibacterial activity in the agar diffusion assay against Staphylococcus aureus, Escherichia coli, Bacillus cereus and Pseudomonas aeruginosa. Forty-two species afforded extracts that showed some degree of activity in one or more of these bioassays.

  10. Chinese Medicinal Leech: Ethnopharmacology, Phytochemistry, and Pharmacological Activities

    Science.gov (United States)

    Dong, Han; Ren, Ji-Xiang; Wang, Jing-Jing; Ding, Li-Shuai; Zhao, Jian-Jun; Liu, Song-Yan; Gao, Hui-Min

    2016-01-01

    Hirudo (Shuizhi in Chinese) is an important Chinese medicine, which possesses many therapeutic properties for the treatment of the cerebral hemorrhage and other thrombosis-related diseases. The phytochemical investigation gave more than 51 compounds including pteridines, phosphatidylcholines, glycosphingolipids, and sterols, as well as some bioactive peptides from the Shuizhi derived from three animal species recorded in the current Chinese Pharmacopoeia. The pharmacological studies on the Shuizhi have revealed various activities such as anticoagulation, antithrombosis, antiatherosclerosis, antiplatelet aggregation, antitumor and anti-inflammatory as well as hemorheology improvement, and protective effects against cerebral ischemia-reperfusion injury. However, some important issues based on the traditional uses of Shuizhi are still not clear. The aim of the present review is to provide comprehensive knowledge on the ethnopharmacology, phytochemistry, and pharmacological activities of Shuizhi. It will provide a potential guidance in exploring main active compounds of Shuizhi and interpreting the action mechanism for the further research. PMID:27274755

  11. Chinese Medicinal Leech: Ethnopharmacology, Phytochemistry, and Pharmacological Activities

    Directory of Open Access Journals (Sweden)

    Han Dong

    2016-01-01

    Full Text Available Hirudo (Shuizhi in Chinese is an important Chinese medicine, which possesses many therapeutic properties for the treatment of the cerebral hemorrhage and other thrombosis-related diseases. The phytochemical investigation gave more than 51 compounds including pteridines, phosphatidylcholines, glycosphingolipids, and sterols, as well as some bioactive peptides from the Shuizhi derived from three animal species recorded in the current Chinese Pharmacopoeia. The pharmacological studies on the Shuizhi have revealed various activities such as anticoagulation, antithrombosis, antiatherosclerosis, antiplatelet aggregation, antitumor and anti-inflammatory as well as hemorheology improvement, and protective effects against cerebral ischemia-reperfusion injury. However, some important issues based on the traditional uses of Shuizhi are still not clear. The aim of the present review is to provide comprehensive knowledge on the ethnopharmacology, phytochemistry, and pharmacological activities of Shuizhi. It will provide a potential guidance in exploring main active compounds of Shuizhi and interpreting the action mechanism for the further research.

  12. 浅论中医与道教%Analysis on Traditional Chinese Medicine and Taoism

    Institute of Scientific and Technical Information of China (English)

    吕宣新; 吕迪阳

    2014-01-01

    道教是中国的本土宗教,中医是中华民族的特色医药学。中医从起源到发展和道教一直密不可分。做一个真正的中医医生,需要了解道教对中医的影响。%Taoism was China's indigenous religion .Traditional Chinese medicine was the Chinese nation's characteristic medicine .From its origins to the development of traditional Chinese medicine and Taoism had been inseparable .Traditional Chinese physician did a real need to understand the impact of Taoism on Chinese medicine .

  13. [Preliminary study on main impacting factors on brand equity of listed traditional Chinese medicine companies].

    Science.gov (United States)

    Tan, Wei; Geng, Dong-Mei; Rong, Xue; Li, Zi; Liu, Wei; Yang, Li; Xu, Si-Qun; Jie, Xiao-Qian

    2013-05-01

    The brand equity is valuable intangible assets of traditional Chinese medicine companies, who are excellent representatives of traditional Chinese medicine enterprises and the most promising ones to good international medicine brands. However, there is still no systematic study on how to correctly evaluate the brand equity of listed traditional Chinese medicine companies at present. To make it clear, the main impacting factors on brand equity of listed traditional Chinese medicine companies, both structured open outline pre-research and closed questionnaire research were adopted for the field survey, and some suggestions for how to protect and enhance the brand equity were also presented on the basis of survey and analysis, in the hope of improving the brand management level of listed traditional Chinese medicine companies, and making a beneficial exploration for the development of brand theory of the traditional Chinese medicine industry. PMID:23944085

  14. Knowledge sharing in Chinese hospitals identifying sharing barriers in traditional Chinese and Western medicine collaboration

    CERN Document Server

    Zhou, Lihong

    2015-01-01

    This book aims to identify, understand and qualify barriers to the patient-centred knowledge sharing (KS) in interprofessional practice of Traditional Chinese Medicine (TCM) and Western Medicine (WM) healthcare professionals in Chinese hospitals.  This collaboration is particularly crucial and unique to China since, contrary to Western practice, these two types of professionals actually work together complimentary in the same hospital. This study adopted a Grounded Theory approach as the overarching methodology to guide the analysis of the data collected in a single case-study design.  A public hospital in central China was selected as the case-study site, at which 49 informants were interviewed by using semi-structured and evolving interview scripts.  The research findings point to five categories of KS barriers: contextual influences, hospital management, philosophical divergence, Chinese healthcare education and interprofessional training.  Further conceptualising the research findings, it is identifie...

  15. [Present situation and development strategies of Chinese medicine preparation in medical institutions].

    Science.gov (United States)

    Wang, Jie; Qiao, Xi-Yao; Lin, Fei

    2015-11-01

    As the actual clinical reflecting of transform Chinese medicine special curative effect, Chinese medicine preparation not only satisfies the need of hospital clinic, scientific research and teaching, but also plays an important role in deepening medical and health system reform, improving people's health level and contributing to the economic growth. However, some problems about administration and approval (tending to western medicine), contraction of the scale, lack of synchronization for clinic and scientific research, and the imbalance of regional development make Chinese medicine preparation move forwards slowly in contradiction. It has not only reduced the effectiveness of the Chinese medicine preparation in hospital clinic, but also brought bad effect on modernized development of Chinese medicine preparation. Research shows that main influencing factors of status quo of Chinese medicine preparation in medical institution include imperfect laws and regulations, high cost than income, and shortage of talents in preparation research. The analysis indicated that the necessary measures to break the contradiction, improve clinical effect of Chinese medicine, and promote the modernization development of Chinese drugs preparation were as follows: government and related departments should strengthen the supporting force in policy by adjusting the examination and approval policy, speeding up dispensing use, reforming pricing system, including into medicare reimbursement, integrating advantage resources and so on; medical institution should actively carry out research and development of traditional Chinese Medicine through drawing the traditional and modern essence, reserving professional talents, and developing characteristic preparation; companies cooperate with hospitals for complementary advantages, which can rapidly transform Chinese medicine preparation into clinical practice.

  16. Genetic authentication of ginsengand other traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    CCHON; YCCHOW; FYZENG; FCCLEUNG

    2003-01-01

    The main objective of this paper is to review the chemical and genetic methods used in authentication ofginseng, especially the recent advances in microsatellite genotyping and its application to the authentication of othertraditional Chinese medicines (TCM). The standardization and modernization of TCM hinge on the authenticationof their botanical identities. Analysis of well-characterized marker compounds is now the most popular method foridentifying the herbal materials and quality control of TCM, eg, ginsenoside profiling for authentication of Panaxspecies. However, in many herbal species the chemical composition of the plant changes with the external environment and processing conditions, which lowers the reliability of these authentication methods. In the light of theadvances in molecular biotechnology in the past few decades, genetic tools are now considered to provide morestandardized and reliable methods for authentication of herbal materials at the DNA level. These genetic toolsinclude random amplified polymorphic DNA (RAPD), DNA fingerprinting using multi-loci probes, restriction fragment length polymorphism (RFLP), amplified fragment length polymorphism (AFLP), and microsatellite markertechnology. The practicality of these methods varies in terms of their sensitivity, reliability, reproducibility, andrunning cost. Using ginseng as an example, we reviewed the advantages and limitations of these molecular tech-niques in TCM authentication. We have developed a set of microsatellite markers from American ginseng that areable to differentiate Panax ginseng and Panax quinquetolius with the resolution down to farm level, ie, confirmationof its botanical identity and origin. Compared with other molecular techniques, microsatellite marker technology ismore robust, accurate, reproducible, reliable, and sensitive. This is essential for large-scale TCM authenticationcenters.

  17. Tragic result of traditional Chinese medicine manipulation: an unusual case report of bilateral anterior shoulder dislocations

    OpenAIRE

    Chen, Chiu-Liang; Chiu, Shin-Lin; Chu, Chiao-Lee; Lan, Shou-Jen

    2015-01-01

    Background In Taiwan, there is a good universal healthcare system to the patients; however, the majority of Taiwanese seek the complementary and alternative medicine when they are injured or ill. The traditional Chinese medicine, which is a branch of complementary alternative medicine, is prevalent in Taiwan. Without proper sequence of maneuvers, either traditional Chinese medicine or conventional medicine might cause unexpected complications. We report a case of 76-year-old woman who was man...

  18. Model Organisms and Traditional Chinese Medicine Syndrome Models

    Directory of Open Access Journals (Sweden)

    Shuang Ling

    2013-01-01

    Full Text Available Traditional Chinese medicine (TCM is an ancient medical system with a unique cultural background. Nowadays, more and more Western countries due to its therapeutic efficacy are accepting it. However, safety and clear pharmacological action mechanisms of TCM are still uncertain. Due to the potential application of TCM in healthcare, it is necessary to construct a scientific evaluation system with TCM characteristics and benchmark the difference from the standard of Western medicine. Model organisms have played an important role in the understanding of basic biological processes. It is easier to be studied in certain research aspects and to obtain the information of other species. Despite the controversy over suitable syndrome animal model under TCM theoretical guide, it is unquestionable that many model organisms should be used in the studies of TCM modernization, which will bring modern scientific standards into mysterious ancient Chinese medicine. In this review, we aim to summarize the utilization of model organisms in the construction of TCM syndrome model and highlight the relevance of modern medicine with TCM syndrome animal model. It will serve as the foundation for further research of model organisms and for its application in TCM syndrome model.

  19. Hybrid de novo genome assembly of the Chinese herbal plant danshen (Salvia miltiorrhiza Bunge)

    OpenAIRE

    Zhang, Guanghui; Tian, Yang; Zhang, Jing; Shu, Liping; Yang, Shengchao; Wang, Wen; Sheng, Jun; Dong, Yang; Chen, Wei

    2015-01-01

    Background Danshen (Salvia miltiorrhiza Bunge), also known as Chinese red sage, is a member of Lamiaceae family. It is valued in traditional Chinese medicine, primarily for the treatment of cardiovascular and cerebrovascular diseases. Because of its pharmacological potential, ongoing research aims to identify novel bioactive compounds in danshen, and their biosynthetic pathways. To date, only expressed sequence tag (EST) and RNA-seq data for this herbal plant are available to the public. We t...

  20. [Research about re-evaluation of screening of traditonal Chinese medicine symptoms item of post-marketing medicine Xuezhikang].

    Science.gov (United States)

    He, Wei; Xie, Yanming; Wang, Yongyan

    2011-10-01

    The purpose of post-marketing Chinese medicine re-evaluation is to identify Chinese medicine clinical indications, while designing scientific and rational of Chinese medicine symptoms items are important to the result of symptoms re-evaluation. This study give screening of traditional Chinese medicine(TCM) symptoms item of post-marketing medicine Xuezhikang re-evaluation as example that reference to principle dyslipidemia clinical research, academic dissertations, Xuezhikang directions, clinical expert practice experience etc. while standardization those symptom names and screening 41 dyslipidemia common symptoms. Furthermore, this paper discuss about the accoerdance and announcements when screening symptoms item, so as to providing a research thread to manufacture PRO chart for post-marketing medicine re-evaluation. PMID:22292395

  1. Accumulation of heavy metals in selected medicinal plants.

    Science.gov (United States)

    Sarma, Hemen; Deka, Suresh; Deka, Hemen; Saikia, Rashmi Rekha

    2011-01-01

    In this review, we evaluate the reports published between 1993 and 2011 that address the heavy metal accumulation in 88 medicinal plant species. We compare the safe limits for heavy metals set by governmental agencies vs. the levels at which such metals actually exist in selected medicinal plants. We also evaluate the uses and effectiveness of medicinal plants in health care, and assess the hazards of medicinal plant uses, in view of the growing worldwide use of medicinal plants. From our extensive review of the literature, we discovered that a maximum permissible level (MPL) of Pb is exceeded in 21 plant medicine species, Cd in 44 species, and Hg in 10 species. Vetiveria zizanioides a potential candidate species for the treatment of cardiovascular diseases absorb a wide range of heavy metals from metal-contaminated soils. We believe that this species is the single most impressive example of a potentially hazardous medicinal plant. Based on our review, we endorse the hypothesis that heavy metal accumulation by medicinal plants is mainly caused by extraction of soluble metals from contaminated soil, sediments and air. One continuing problem in protecting consumers of plant-based medicines is that permissible levels of all heavy metals in herbal medicine have not yet been standardized by regulating governmental entities. Moreover, there are few limit tests that exist for heavy metal content of medicinal plants, or permissible limits for essential dietary minerals, in most medicinal plants. The dearth of such limits hamstrings development of medicinal plant research and delays the release of either new or improved versions of medicinal plants or their components. In the present review, we emphasize that medicinal plants are often subjected to heavy metal contamination and that the levels at which these heavy metals sometimes occur exceeds permissible levels for some species. Therefore, collecting medicinal plants from areas that are, or may be, contaminated should be

  2. Evaluating Medicinal Plants for Anticancer Activity

    Directory of Open Access Journals (Sweden)

    Elisha Solowey

    2014-01-01

    Full Text Available Plants have been used for medical purposes since the beginning of human history and are the basis of modern medicine. Most chemotherapeutic drugs for cancer treatment are molecules identified and isolated from plants or their synthetic derivatives. Our hypothesis was that whole plant extracts selected according to ethnobotanical sources of historical use might contain multiple molecules with antitumor activities that could be very effective in killing human cancer cells. This study examined the effects of three whole plant extracts (ethanol extraction on human tumor cells. The extracts were from Urtica membranacea (Urticaceae, Artemesia monosperma (Asteraceae, and Origanum dayi post (Labiatae. All three plant extracts exhibited dose- and time-dependent killing capabilities in various human derived tumor cell lines and primary cultures established from patients’ biopsies. The killing activity was specific toward tumor cells, as the plant extracts had no effect on primary cultures of healthy human cells. Cell death caused by the whole plant extracts is via apoptosis. Plant extract 5 (Urtica membranacea showed particularly strong anticancer capabilities since it inhibited actual tumor progression in a breast adenocarcinoma mouse model. Our results suggest that whole plant extracts are promising anticancer reagents.

  3. [Analysis of varieties and standards of Leguminosae plants used in Tibetan medicine].

    Science.gov (United States)

    Cao, Lan; Du, Xiao-lang; Zhong, Wei-hong; Zhong, Wei-jin; He, Jun-wei; Mu, Ze-jing; Zhong, Guo-yue

    2015-12-01

    In this paper, the domestic varieties and quality standard of Leguminosae medicinal plants used in Tibetan medicine were analyzed. The results showed that there were 36 genera and 142 species (including varieties), as well as 64 medicinal materials varieties of Leguminosae plants were recorded in relevant literatures. In relevant Tibetan standards and literatures, there are great differences in varieties, sources, used parts, and efficacy of medicinal plants. Among them, about 38.0% (including 54 species) of the endemic plants, about 25.4% (including 36 species) of the original plants have medicinal standard legal records, except 9 kinds of traditional Chinese medicine general quality standard more fairly completed, the most varieties have only description about characters, identification, etc. Therefore it is necessary to reinforce study for the herbal textual, resources and the use present situation, chemical components and biological activity, quality standard, medicinal terms specification, to promote establishment of quality standard system for variety-terminologies-sources of Tibetan medicinal plants. PMID:27245043

  4. [Analysis of varieties and standards of Scrophulariaceae plants used in Tibetan medicine].

    Science.gov (United States)

    Cao, Lan; Mu, Ze-jing; Zhong, Wei-hong; Zhong, Wei-jin; He, Jun-wei; Du, Xiao-lang; Zhong, Guo-yue

    2015-12-01

    In this paper, the popular domestic varieties and quality standard of Scrophulariaceae plants used in Tibetan medicine were analyzed. The results showed that there were 11 genera and 99 species (including varieties), as well as 28 medicinal materials varieties of Scrophulariaceae plants were recorded in the relevant literatures. In relevant Tibetan standards arid literatures, there are great differences in varieties, sources, parts, and efficacies of medicinal plant. Among them, about 41.4% (including 41 species) of endemic plants, about 15.2% (including 15 species) of the original plants have medicinal standard legal records, except the medicinal materials of Scrophalaria ningpoensis, Lagotis brevituba, Picrorhiza scrophulariiflora, Veronica eriogyne general, most varieties have not completed quality standard. Consequently it is necessary to reinforce the herbal textual, resources and the use present situation investigation, the effects of the species resources material foundation and biological activity, quality standard, specification the medical terms of the plants, and promote Tibetan medicinal vareties-terminologies-sources such as the criterion and quality standard system for enriching the varieties of Tibetan medicinal materials and Chinese medicinal resources. PMID:27141684

  5. Cytotoxicity Potentials of Eleven Bangladeshi Medicinal Plants

    OpenAIRE

    Amina Khatun; Mahmudur Rahman; Tania Haque; Md. Mahfizur Rahman; Mahfuja Akter; Subarna Akter; Afrin Jhumur

    2014-01-01

    Various forms of cancer are rising all over the world, requiring newer therapy. The quest of anticancer drugs both from natural and synthetic sources is the demand of time. In this study, fourteen extracts of different parts of eleven Bangladeshi medicinal plants which have been traditionally used for the treatment of different types of carcinoma, tumor, leprosy, and diseases associated with cancer were evaluated for their cytotoxicity for the first time. Extraction was conceded using methano...

  6. [Enlightenment of adverse reaction monitoring on safety evaluation of traditional Chinese medicines].

    Science.gov (United States)

    Song, Hai-bo; Du, Xiao-xi; Ren, Jing-tian; Yang, Le; Guo, Xiao-xin; Pang, Yu

    2015-04-01

    The adverse reaction monitoring is important in warning the risks of traditional Chinese medicines at an early stage, finding potential quality problems and ensuring the safe clinical medication. In the study, efforts were made to investigate the risk signal mining techniques in line with the characteristics of traditional Chinese medicines, particularly the complexity in component, processing, compatibility, preparation and clinical medication, find early risk signals of traditional Chinese medicines and establish a traditional Chinese medicine safety evaluation system based on adverse reaction risk signals, in order to improve the target studies on traditional Chinese medicine safety, effective and timely control risks and solve the existing frequent safety issue in traditional Chinese medicines. PMID:26281610

  7. The Main Anticancer Bullets of the Chinese Medicinal Herb, Thunder God Vine

    Directory of Open Access Journals (Sweden)

    Zi Liu

    2011-06-01

    Full Text Available The thunder god vine or Tripterygium wilfordii Hook. F. is a representative Chinese medicinal herb which has been used widely and successfully for centuries in treating inflammatory diseases. More than 100 components have been isolated from this plant, and most of them have potent therapeutic efficacy for a variety of autoimmune and inflammatory diseases. In the past four decades, the anticancer activities of the extracts from this medicinal herb have attracted intensive attention by researchers worldwide. The diterpenoid epoxide triptolide and the quinone triterpene celastrol are two important bioactive ingredients that show a divergent therapeutic profile and can perturb multiple signal pathways. Both compounds promise to turn traditional medicines into modern drugs. In this review, we will mainly address the anticancer activities and mechanisms of action of these two agents and briefly describe some other antitumor components of the thunder god vine.

  8. Antimicrobial activity of some Iranian medicinal plants

    Directory of Open Access Journals (Sweden)

    Ghasemi Pirbalouti Abdollah

    2010-01-01

    Full Text Available The major aim of this study was to determine the antimicrobial activity of the extracts of eight plant species which are endemic in Iran. The antimicrobial activities of the extracts of eight Iranian traditional plants, including Hypericum scabrum, Myrtus communis, Pistachia atlantica, Arnebia euchroma, Salvia hydrangea, Satureja bachtiarica, Thymus daenensis and Kelussia odoratissima, were investigated against Escherichia coli O157:H7, Bacillus cereus, Listeria monocytogenes and Candida albicans by agar disc diffusion and serial dilution assays. Most of the extracts showed a relatively high antimicrobial activity against all the tested bacteria and fungi. Of the plants studied, the most active extracts were those obtained from the essential oils of M. communis and T. daenensis. The MIC values for active extract and essential oil ranged between 0.039 and 10 mg/ml. It can be said that the extract and essential oil of some medicinal plants could be used as natural antimicrobial agents in food preservation. .

  9. Burn healing plants in Iranian Traditional Medicine

    Directory of Open Access Journals (Sweden)

    Sh. Fahimi

    2015-11-01

    Full Text Available Burns are known as one of the most common forms of injury with devastating consequences. Despite the discovery of several antiseptics, burn wound healing has still remained a challenge to modern medicine. Herbal products seem to possess moderate efficacy with no or less toxicity and are less expensive compared to synthetic drugs. Burn is a well-known disorder in Iranian Traditional Medicine (ITM. Iranian physicians have divided burns into various types based on the cause and recommended treatment for each type. According to ITM references, herbal therapy was the major treatment prescribed by Iranian physicians for burns. In the present study, seven ancient Iranian medical texts were screened for the herbs with burn healing effects along with their applied dosage forms. The medicinal herbs were listed and scored based on the frequency of their repetition. Moreover, the best scientific name that was suitable for each plant as well as surveying modern studies about their biological effects has been carried out. In our investigation eighteen plants with seven topical application categories have been obtained as the most frequent herbs for burn healing in ITM. Modern studies have revealed that these plants have shown some biological activities such as anti-inflammatory, antimicrobial and antioxidant effects which might establish the relationship between the mentioned activities and burn wound healing property. This list can provide a suitable resource for future researches in the field of burn treatment.

  10. Determination of Amino Acids in Edible Fungi planted with Chinese Medicine Residue%中药渣栽培食用菌中氨基酸含量的测定与分析

    Institute of Scientific and Technical Information of China (English)

    金茜; 曾启华; 李华刚; 文光均; 张素英

    2015-01-01

    研究了中药渣栽种的食用菌中氨基酸的成分及含量。食用菌样品经酸水解蛋白质技术预处理后,采用氨基酸自动分析仪进行检测分析,结果表明:中药渣栽种的食用菌中氨基酸种类齐全,氨基酸总量达21.34 g/100g,其中必需氨基酸的含量为9.01g/100g,含量最高的是亮氨酸(1.77g/100g),以后依次是缬氨酸(1.43 g/100g)、赖氨酸(1.21g/100g)、苯丙氨酸(1.18g/100g);用药渣栽种的食用菌中游离氨基酸的含量高达20.70g/100g,谷氨酸含量高达3.33g/100g,天冬氨酸达2.17g/100g,丰富多样的氨基酸的检出可为深入探讨食用菌独特的风味提供重要参考。%Components and contents of Amino Acids in edible fungi planted with Chinese medicine residue were researched in this ar-ticle. Detection and analysis were achieved by Automatic amino acid analyzer, after pretreatment of edible fungi samples, using Tech-nology of acid-hydrolysis amino acid. According to the results, the amino acids in edible fungi are very rich, totaled 21.34 g/100g, in which the content of essential amino acids were 9.01 g/100 g, such as leucine has the maximum content with 1.77g/100g;the second is valine with 1.43 g/100g;then lysine and phenylalanine with 1.21and 1.18 g/100g respectively. Free amino acids Totaled 20.70g/100g, glutamate and aspartic acid were 3.33 and2.17g/100g.It could provide very useful conference for studying the special fla-vor from the edible fungi.

  11. Barriers and countermeasures in developing traditional Chinese medicine in Europe.

    Science.gov (United States)

    Liu, Yunfang; Yang, Zhiping; Cheng, Jing; Fan, Daiming

    2016-09-01

    Traditional Chinese medicine (TCM) is one of the unique cultural treasures of Chinese; it represents a significant feature and prominent advantage of the healthcare cause in China. Data in this paper were fromWorld Health Organization, Chinese Bureau of Statistics, China National Knowledge Infrastructure, and PubMed. In recent years, TCM has established a solid foundation in Europe, which made great strides in legislation, education, research, and international exchange, and has enjoyed a vast development space in the continent. Now, TCM is embracing unprecedented development opportunities in Europe. At the same time, the stiff international competition poses a grave threat to China's TCM industry. With multiple cultural, legal, and institutional challenges, as well as talent shortages in the way, TCM is now facing many difficulties in Europe. To fully prepare and enact active and vigorous steps to seize opportunities, we should have a clear picture about the serious challenges hampering TCM development in Europe. The TCM development at overseas markets has shifted from a spontaneous trade activity into a national strategy spearheaded by the government and participated in by multiple stakeholders. We should make a systematic, comprehensive, and sustainable push in fields such as TCM therapy, healthcare, education, research, culture, and industry development. The ultimate goal is to bring TCMs to the global market and allow them to play a role in safeguarding public health along with modern medicines. PMID:27465827

  12. An overview on adverse drug reactions to traditional Chinese medicines.

    Science.gov (United States)

    Chan, Kelvin; Zhang, Hongwei; Lin, Zhi-Xiu

    2015-10-01

    The safe use of Chinese materia medica (CMM) and products in traditional Chinese medicine (TCM) practice conventionally relies on correct pharmacognostic identification, good agricultural and manufacturing practices based on pharmacopoeia standards and rational/correct CMM combinations with TCM-guided clinical prescribing. These experience-based principles may not absolutely ensure safety without careful toxicological investigations when compared with development of new pharmaceutical drugs. Clinically observed toxicity reports remain as guidance for gathering toxicological evidence, though essential as pharmacovigilance, but are considered as late events for ensuring safety. The overview focuses on the following factors: global development of TCM that has affected conventional healthcare; examples of key toxic substances in CMM; reported adverse drug reactions (ADRs) consequential to taking CMM and TCM products; and proposals on rational approaches to integrate the knowledge of biomedical science and the principles of TCM practice for detecting early ADRs if both TCM products and orthodox drugs are involved. It is envisaged that good control of the quality and standards of CMM and proprietary Chinese medicines can certainly reduce the incidence of ADRs in TCM practice when these medications are used. PMID:25619530

  13. Experimental research of integrative Chinese medicine in multiple sclerosis

    Institute of Scientific and Technical Information of China (English)

    Ke-Ying Zhu; Zheng Kang; Yan Chen; Gen-Cheng Wu; Jun Wang

    2016-01-01

    多发性硬化症是一种严重的神经退行性疾病,会给患者及其家属带来难以估量的痛苦及负担,且目前没有可以根治的办法。因此,有必要从不同的医学体系中寻找能够治疗多发性硬化的治疗方法。中医是最为主要的一类传统与替代医学疗法,且在世界范围内长期被广泛用于治疗包括多发性硬化在内的神经系统疾病。本文主要总结了不同中医疗法在多发性硬化动物模型——实验性变态反应性脑脊髓炎模型中的研究现状,包括中药复方,中药提取物如石杉碱甲、毛萼乙素、姜黄素等,以及针灸。这些研究为多发性硬化证的治疗提供了新的思路,同时也有利于进一步阐明中医中医治疗多发性硬化症的疗效机制。%Multiple sclerosis (MS) is a severe neurodegenerative disease which brings overwhelming sufferings to patients and their families with no radical cure heretofore. Thus, studies of different medicine field and diverse treating methods aiming at the cure for MS should be promoted. Traditional Chinese medicine (TCM) as one of the most important complementary and alternative medicine (CAM), has long been applied to treat MS in China and other nervous system diseases worldwide. Our review aims to summarize the findings of Chinese herbal medicine and acupuncture in the prevention and treatment on animal model of MS, mainly based on experimental autoimmune encephalomyelitis (EAE) model. In this review, experimental research advances of Traditional Chinese medicine in the studies of MS are involved, including Chinese herb decoctions, herb extracts like huperzine A, Eriocalyxin B, Curcumin and also, acupuncture. All of this researches hew out new thoughts towards the treatment of MS and concomitantly, the understanding of the effective mechanism of TCM on MS.

  14. [Evolution, characteristics and enlightenment of self-innovation of traditional Chinese medicine industry].

    Science.gov (United States)

    Feng, Zhi-pei; Tao, Qun-shan; Peng, Dai-yin; Wei, Hua

    2015-06-01

    Traditional Chinese medicine industry is China's strategic emerging industry with great potential for self-innovation. Traditional Chinese medicine industry has successively experienced four stages which are the foundation (laying stage), the core status (establishing stage), the modern system (exploring stage), and the modernization system (constructing stage). Throughout the evolution of the self-innovation in traditional Chinese medicine industry, it presents distinct characteristics which we can explore the beneficial enlightenment. PMID:26552191

  15. Reason Analysis and Risk Prevention of Soaring Price of Traditional Chinese Medicinal Materials

    OpenAIRE

    Zhao, Huan; Liu, Jian-qiu; Qu, Kai-yue; Feng, Li; He, Yi

    2011-01-01

    In recent years, the price of traditional Chinese medicinal materials soars continuously, and the resulting price risk increasingly looms large, which has critically affected midstream and downstream industries and peoples' demand for drug, and imperiled healthy and orderly development of traditional Chinese medicinal industries. Based on the status quo of continuous skyrocketing price of traditional Chinese medicinal materials at present, we winkle out the root cause of soaring price as foll...

  16. Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy

    OpenAIRE

    Xuanbin Wang; Yibin Feng; Ning Wang; Fan Cheung; Hor Yue Tan; Sen Zhong; Charlie Li; Seiichi Kobayashi

    2014-01-01

    Chinese medicines have long history in treating cancer. With the growing scientific evidence of biomedical researches and clinical trials in cancer therapy, they are increasingly accepted as a complementary and alternative treatment. One of the mechanisms is to induce cancer cell death. Aim. To comprehensively review the publications concerning cancer cell death induced by Chinese medicines in recent years and provide insights on anticancer drug discovery from Chinese medicines. Materials and...

  17. A new dawn for the use of traditional Chinese medicine in cancer therapy

    OpenAIRE

    Wei Ming Q; Liu Gang; Parekh Harendra S

    2009-01-01

    Abstract Although traditional Chinese medicine has benefitted one fifth of the world's population in treating a plethora of diseases, its acceptance as a real therapeutic option by the West is only now emerging. In light of a new wave of recognition being given to traditional Chinese medicine by health professionals and regulatory bodies in the West, an understanding of their molecular basis and highlighting potential future applications of a proven group of traditional Chinese medicine in th...

  18. [Process on researching methods of ecology of Chinese traditional medicine resources].

    Science.gov (United States)

    Zhou, Yingqun; Cao, Hailu; Zhao, Runhuai; Chen, Shilin

    2011-02-01

    Though the study on ecology of Chinese traditional medicinal resources methods has achieved great progress in recent years, it is not able to catch the pace of the development of ecology science. Based on the analysis of recent literatures about ecology development trend and Chinese traditional medicinal ecology methods, the progress of Chinese traditional medicinal ecology methods was reviewed, and future study trend was discussed.

  19. Analysis on the influencing factors of the farmers’ willingness to plant Chinese herbal medicine and its hierarchical configuration:A case study in Longxi%农户中药材种植意愿影响因素及递阶结构分析--以陇西县为例

    Institute of Scientific and Technical Information of China (English)

    王彩红; 段小红; 姜燕飞

    2016-01-01

    基于陇西县150份中药材种植户调查数据,从户主特征、家庭特征、中药材种植特征及外部环境等方面选取变量,运用 logistic-ISM 模型分析农户中药材种植意愿的影响因素及其层级关系。结果显示:文化程度、中药材收入占比、种植年数、中药材销售情况、价格满意程度、政府资金支持对农户中药材种植意愿有显著正向影响,年龄、外出务工劳动力占比、种植成本有显著负向影响。其中,中药材收入占比是表层直接因素,外出务工劳动力占比、种植年数、种植成本、中药材销售情况、价格满意程度、政府资金支持为中层间接因素,年龄和文化程度为深层根源因素。%Based on survey data of 150 households in Longxi and applying the logistic-ISM model, selecting the variable from the dimensions of the features of the household head, family characteristics, Chinese herbal medicine planting characteristics and the external environment, this paper explored the influencing factors that affect farmers’ willingness to plant Chinese herbal medicine, and analyzed the hierarchical relationship among various influencing factors. The results showed that culture degree, proportion of Chinese herbal medicine income, planting years, sales situation, price satisfaction and government funding support positively affect the willingness of households, age, proportion of migrant labour and cost negatively affect the willingness of households. Among them, proportion of Chinese herbal medicine income is surface factors, proportion of migrant labour, cost, planting years, sales situation, price satisfaction and government funding support are middle-level indirect factors, age and culture degree as deep root of factors.

  20. Safety concerns of herbal products and traditional Chinese herbal medicines: dehydropyrrolizidine alkaloids and aristolochic acid.

    Science.gov (United States)

    Stegelmeier, Bryan L; Brown, Ammon W; Welch, Kevin D

    2015-12-01

    In many countries, including the United States, herbal supplements, tisanes and vegetable products, including traditional Chinese medicines, are largely unregulated and their content is not registered, monitored or verified. Consequently, potent plant toxins including dehydropyrrolizidine alkaloids and other potential carcinogens can contaminate these products. As herbal and food supplement producers are left to their own means to determine the safety and purity of their products prior to marketing, disturbingly often good marketing practices currently in place are ignored and content is largely undocumented. Historical examples of poisoning and health issues relating to plant material containing dehydopyrrolizidine alkaloids and aristolochic acids were used as examples to demonstrate the risk and potential toxicity of herbal products, food supplements, or traditional medicines. More work is needed to educate consumers of the potential risk and require the industry to be more responsible to verify the content and insure the safety of their products. PMID:26152912

  1. [Analysis of toxicity of traditional Chinese herbal medicine and its connotation].

    Science.gov (United States)

    Liang, Qi; Xie, Ming

    2009-02-01

    Based on traditional Chinese medicine theory and clinical experience, traditional Chinese herbal drug toxicity has its own special connotation. From the perspective of history and logic, the different comprehension of toxicity between Western medicine and traditional Chinese medicine was discussed after retracing the meaning of "drug toxicity" in traditional Chinese medicine. The authors suggest that it's not feasible to study the Chinese medicine coping mechanically and applying indiscriminately the concept and the research idea about modern drug toxicity since there is different understanding of "drug toxicity" between traditional Chinese medicine and Western medicine. Many control elements are involved in the use of traditional Chinese herbal drugs, and Chinese drug components and actions are complex as compared with Western drugs. More and more drugs with toxicity will be found due to the relativity of drug toxicity. Currently, the study of Chinese drug toxicity should pay more attention to the relation between the toxicity and Chinese drug nature, compatibility and the corresponding disease or syndrome pattern after making definition of Chinese drug toxicity and its connotation. PMID:19216849

  2. [Problems in quality standard research of new traditional Chinese medicine compound].

    Science.gov (United States)

    Zhou, Gang; He, Yan-Ping

    2014-09-01

    The new traditional Chinese medicine compound is the main part of the research of new drug of traditional Chinese medicine (TCM), and the new Chinese herbal compound reflects the characteristics of TCM theory. The new traditional Chinese medicine compound quality standard research is one of the main content of pharmaceutical research, and is also the focus of the new medicine pharmaceutical evaluation content. Although in recent years the research level of new traditional Chinese medicine compound has been greatly improved, but the author during the review found still some common problems existing in new traditional Chinese medicine compound quality standard research data, this paper analyzed the current quality standards for new traditional Chinese medicine compound and the problems existing in the research data, respectively from measurement of the content of index selection, determine the scope of the content, and the quality standard design concept, the paper expounds developers need to concern. The quality of new traditional Chinese medicine compound quality standard is not only itself can be solved, but quality standards is to ensure the key and important content of product quality, improving the quality of products cannot do without quality standards. With the development of science and technology, on the basis of quality by design under the guidance of the concept, new traditional Chinese medicine compound quality standard system will be more scientific, systematic and perfect.

  3. [The technological innovation strategy for quality control of Chinese medicine based on Big Data].

    Science.gov (United States)

    Li, Zhen-hao; Qian, Zhong-zhi; Cheng, Yi-yu

    2015-09-01

    The evolution of the quality control concepts of medical products within the global context and the development of the quality control technology of Chinese medicine are briefly described. Aimed at the bottlenecks in the regulation and quality control of Chinese medicine, using Big Data technology to address the significant challenges in Chinese medicine industry is proposed. For quality standard refinements and internationalization of Chinese medicine, a technological innovation strategy encompassing its methodology, and the R&D direction of the subsequent core technology are also presented. PMID:26978975

  4. Anti-cancer natural products isolated from chinese medicinal herbs

    Directory of Open Access Journals (Sweden)

    Wu Guosheng

    2011-07-01

    Full Text Available Abstract In recent years, a number of natural products isolated from Chinese herbs have been found to inhibit proliferation, induce apoptosis, suppress angiogenesis, retard metastasis and enhance chemotherapy, exhibiting anti-cancer potential both in vitro and in vivo. This article summarizes recent advances in in vitro and in vivo research on the anti-cancer effects and related mechanisms of some promising natural products. These natural products are also reviewed for their therapeutic potentials, including flavonoids (gambogic acid, curcumin, wogonin and silibinin, alkaloids (berberine, terpenes (artemisinin, β-elemene, oridonin, triptolide, and ursolic acid, quinones (shikonin and emodin and saponins (ginsenoside Rg3, which are isolated from Chinese medicinal herbs. In particular, the discovery of the new use of artemisinin derivatives as excellent anti-cancer drugs is also reviewed.

  5. Cultural Connotation of Plant Words in English and Chinese

    Institute of Scientific and Technical Information of China (English)

    张博明

    2007-01-01

    Cultural connotation and denotative meaning of plant terms in English and Chinese are of great signification in research.It is advisable to do the research from the following four aspects: a.plant terms with similar cultural connotation in English and Chinese; b.plant terms with different cultural connotation in English and Chinese; c.gaps of lexical plant terms in English and Chinese; d.peculiarity of plant termsin English and Chinese. It can be see clearly through the contrast and analysis of plant terms in these two languages that plant terms in any language are not only the symbol of that plant.Cultural differences have left a deep cultural marking on plant terms,maki ng these words very rich in cultural connotation.So we should make great effort in understanding their cultural connotation in order to have a good command of these words.

  6. 纳米中药制剂的研究介绍%Introduction of nano chinese medicine

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ Traditional Chinese medicine has been used for thousands of years, and has been contributing to human health. It is considered as a great treasure of mankind. However, nowadays, Traditional Chinese medicine falls behind of modern medicine. It has not been accepted extensively in the worldwide. How can we change this situation? Modernizing traditional Chinese medicine is an effective way. We must improve traditional Chinese medicine with modern science and technology.

  7. Discrimination of Chinese Herbal Medicine by Machine Olfaction

    Directory of Open Access Journals (Sweden)

    Yawen Shao

    2013-02-01

    Full Text Available “Small Sample Size” (SSS problem would occur while using linear discriminant analysis (LDA algorithm with traditional Fisher criterion if the within-class scatter matrix is singular. The combination of maximum scatter difference (MSD criterion and LDA algorithm for solve SSS problem is described. It is employed to detect three kinds of Chinese herbal medicines from different growing areas by machine olfaction. Compared with PCA or PCA + LDA algorithm, the classification result was enhanced. It works out that only a few samples of Anhui Atractylodes are classified incorrectly, however, the classification rate reaches 97.8%.

  8. [Origin and development of umbilical therapy in traditional Chinese medicine].

    Science.gov (United States)

    Zhang, Xue-Wei; Jia, Hong-Ling

    2014-06-01

    The origin and development of umbilical therapy in traditional Chinese medicine is explored from related literature in the history. As a result, the Shang period is regarded as initial period of umbilical therapy, while periods from Han Dynasty, Jin Dynasty and Southern-Northern Dynasties to Sui Dynasty and Tang Dynasty could be taken as stage of primary development. Time from Song Dynasty, Jin Dynasty and Yuan Dynasty to Ming and Qing Dynasties is believed as mature stage. Also the manipulation, application principle, indications and contraindications of umbilical therapy are explained. A brief overview of modern development of umbilical therapy is also described. PMID:25112106

  9. [Summary and analysis of safety warning on clinical application of anti-cold Chinese patent medicine preparations].

    Science.gov (United States)

    Lai, Xiao-xiao; Lin, Hua; Luo, Yi-ni; Wang, Ying-yan; Duan, Xiao-hong; Wang, Lin; Luo, Rui; Chen, Yan-hong

    2015-04-01

    In China, many surveys have shown that most people do not have a correct understanding about cold and administration of anti-cold Chinese patent medicine preparations. The author conducted a systematic summary and analysis on the actual application of anti-cold Chinese patent medicine preparations as well as the warning on safe application of anti-cold Chinese patent medicine preparations in Clinical Medication Information of China Pharmacopoeia, in the expectation of reducing the blind application of anti-cold Chinese patent medicine preparations and providing traditional Chinese medicine pharmacists new ideas in monitoring the safe application of exterior syndrome-relieving Chinese patent medicine preparations. PMID:26281605

  10. Touriam Health Care Center of Xiyuan Hospital China Academy of Traditioal Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Brief Introduction to Xiyuan Hospital Xiyuan Hospital of China Academy of Traditional Chinese Medicine (TCM) was founded in 1955.It is a large comprehensive hospital directly attached to the Chinese Ministry of Health and State Administration of TOM. This hospital governs First Clinical Medical Institute, Gerontology Institute and Clinical Pharmacological Institute of China Academy of TOM, and Clinical Pharmacological Base of the Health Ministry. It is a component of WHO Collaborating Center for Traditional Medicine. It also administers the Agency of Chinese Journal of Integrated Traditional Chinese and Western Medicine, the Society of Clinical Pharmacology of Chinese Drugs of China TOM Association, the Professional Committee of Hematology and Activating Blood-circulation and Removing Blood Stasis of Chinese Society of Integrated Traditional Chinese and Western Medicine.

  11. Use of Chinese medicine by cancer patients: a review of surveys

    Directory of Open Access Journals (Sweden)

    Smith Caroline A

    2011-06-01

    Full Text Available Abstract Chinese medicine has been used to treat a variety of cancer-related conditions. This study aims to examine the prevalence and patterns of Chinese medicine usage by cancer patients. We reviewed articles written in English and found only the Chinese medicine usage from the studies on complementary and alternative medicine (CAM. Seventy four (74 out of 81 articles reported rates of CAM usage ranging from 2.6 to 100%. Acupuncture was reported in 71 out of 81 studies. Other less commonly reported modalities included Qigong (n = 17, Chinese herbal medicine (n = 11, Taichi (n = 10, acupressure (n = 6, moxibustion (n = 2, Chinese dietary therapy (n = 1, Chinese massage (n = 1, cupping (n = 1 and other Chinese medicine modalities (n = 19. This review also found important limitations of the English language articles on CAM usage in cancer patients. Our results show that Chinese medicine, in particular Chinese herbal medicine, is commonly used by cancer patients. Further research is warranted to include studies not written in English.

  12. Drug metabolism and pharmacokinetics of nanodrugs from Chinese medicines and natural products.

    Science.gov (United States)

    Liu, Chang-Xiao; Si, Duan-Yun; Xiao, Xue-Feng; He, Xin; Li, Ya-Zhuo

    2012-06-01

    Over the past few years, nanoscale Chinese medicine has become one of focuses in modern Chinese medicine research. There is an increasing need for a more systematic study on the basic issues involved in traditional Chinese medicine and a more active participation of researchers in the application area of nanoscale traditional Chinese drugs. In this review, author analyzed the current applications of nanotechnology in research and development of drugs from natural products and herbal medicines involving traditional Chinese medicines, and also discussed the bio-medicinal evaluation issues on ADME including bio-distribution and metabolism of nanodrugs. Author noted that great challenges faced in nanodrugs from herb drugs and natural products are the follows: (1) the first challenge is to prepare nanodrug delivery system and quantitatively evaluate the therapeutic effects and safety; (2) the second challenge is to clarify the concrete metabolism course; and (3) the third challenge is to study the pharmacokinetics of nanodrugs. PMID:22475334

  13. A Computer Aided System for Tropical Leaf Medicinal Plant Identification

    Directory of Open Access Journals (Sweden)

    Yeni Herdiyeni

    2013-01-01

    Full Text Available The objective of this paper is to develop a computer aided system for leaf medicinal plant identification using ProbabilisticNeural Network. In Indonesia only 20-22% of medicinal plants have been cultivated. Generally, identification process of medicinalplants has been done manually by a herbarium taxonomist using guidebook of taxonomy/dendrology. This system is designed to helptaxonomist to identify leaf medicinal plant automatically using acomputer-aided system. This system uses three features of leaf toidentify the medicinal plant, i.e., morphology, shape, and texture. Leaf is used in this system for identification because easily to find.To classify medicinal plant we used Probabilistic Neural Network. The features will be combined using Product Decision Rule (PDR.The system was tested on 30 species medicinal plant from Garden of Biopharmaca Research Center and Greenhouse Center of Exsitu Conservation of Medicinal Indonesian Tropical Forest Plants, Faculty of Forestry, Bogor Agriculture University, Indonesia.Experiment results showed that the accuracy of medicinal plant identification using combination of leaf features increase until74,67%.The comparative analysis of leaf features has been performed statistically. It showed that shape is a dominant features for plant identification. This system is very promising to help people identify medicinal plant automatically and for conservation and utilization of medicinal plants.

  14. Therapeutic Effects of Integrated Traditional Chinese Medicine and Western Medicine in Treating Severe Acute Respiratory Syndrome

    Institute of Scientific and Technical Information of China (English)

    王融冰; 刘军民; 江宇泳; 吴云忠; 王晓静; 池频频; 孙凤霞; 高连印

    2003-01-01

    Objective: To improve the effects of treatment of severe acute respiratory syndrome (SARS) and to explore the clinical significance of integrated traditional Chinese medicine and western medicine (ICWM) in the treatment of SARS and its influence on the chief indexes in the process of the disease. Methods: The clinical study involving observation of 135 patients of SARS was conducted in the randomized, synchronously controlled and open way. The patients were divided into two groups, 68 in the ICWM group and 67 in the control group, all of whom were treated with the same basic treatment of western medicine, but to the ICWM group, Chinese drugs for clearing Heat, detoxifying and removing Dampness were given additionally. The comprehensive effect on relieving fever, cell-mediated immunity, pulmonary inflammation and secondary infection was compared between the two groups. Results: The therapeutic effect in the ICWM group was better than that in the control group in such aspects as steadily lowering body temperature, alleviating general symptoms, accelerating the absorption of pulmonary infiltration and easing cellular immunity suppression. Conclusion: The therapeutic effect of ICWM is better in treating SARS than that of western medicine alone.

  15. Cytotoxic Effects of Bangladeshi Medicinal Plant Extracts

    Directory of Open Access Journals (Sweden)

    Shaikh J. Uddin

    2011-01-01

    Full Text Available To investigate the cytotoxic effect of some Bangladeshi medicinal plant extracts, 16 Bangladeshi medicinal plants were successively extracted with n-hexane, dichloromethane, methanol and water. The methanolic and aqueous extracts were screened for cytotoxic activity against healthy mouse fibroblasts (NIH3T3 and three human cancer-cell lines (gastric: AGS; colon: HT-29; and breast: MDA-MB-435S using the MTT assay. Two methanolic extracts (Hygrophila auriculata and Hibiscus tiliaceous and one aqueous extract (Limnophila indica showed no toxicity against healthy mouse fibroblasts, but selective cytotoxicity against breast cancer cells (IC50 1.1–1.6 mg mL−1. Seven methanolic extracts from L. indica, Clerodendron inerme, Cynometra ramiflora, Xylocarpus moluccensis, Argemone mexicana, Ammannia baccifera and Acrostichum aureum and four aqueous extracts from Hygrophila auriculata, Bruguiera gymnorrhiza, X. moluccensis and Aegiceras corniculatum showed low toxicity (IC50 > 2.5 mg mL−1 against mouse fibroblasts but selective cytotoxicity (IC50 0.2–2.3 mg mL−1 against different cancer cell lines. The methanolic extract of Blumea lacera showed the highest cytotoxicity (IC50 0.01–0.08 mg mL−1 against all tested cell lines among all extracts tested in this study. For some of the plants their traditional use as anticancer treatments correlates with the cytotoxic results, whereas for others so far unknown cytotoxic activities were identified.

  16. Clinical research of traditional Chinese medicine in big data era.

    Science.gov (United States)

    Zhang, Junhua; Zhang, Boli

    2014-09-01

    With the advent of big data era, our thinking, technology and methodology are being transformed. Data-intensive scientific discovery based on big data, named "The Fourth Paradigm," has become a new paradigm of scientific research. Along with the development and application of the Internet information technology in the field of healthcare, individual health records, clinical data of diagnosis and treatment, and genomic data have been accumulated dramatically, which generates big data in medical field for clinical research and assessment. With the support of big data, the defects and weakness may be overcome in the methodology of the conventional clinical evaluation based on sampling. Our research target shifts from the "causality inference" to "correlativity analysis." This not only facilitates the evaluation of individualized treatment, disease prediction, prevention and prognosis, but also is suitable for the practice of preventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine (TCM), and for the post-marketing evaluation of Chinese patent medicines. To conduct clinical studies involved in big data in TCM domain, top level design is needed and should be performed orderly. The fundamental construction and innovation studies should be strengthened in the sections of data platform creation, data analysis technology and big-data professionals fostering and training.

  17. Clinical research of traditional Chinese medicine in big data era.

    Science.gov (United States)

    Zhang, Junhua; Zhang, Boli

    2014-09-01

    With the advent of big data era, our thinking, technology and methodology are being transformed. Data-intensive scientific discovery based on big data, named "The Fourth Paradigm," has become a new paradigm of scientific research. Along with the development and application of the Internet information technology in the field of healthcare, individual health records, clinical data of diagnosis and treatment, and genomic data have been accumulated dramatically, which generates big data in medical field for clinical research and assessment. With the support of big data, the defects and weakness may be overcome in the methodology of the conventional clinical evaluation based on sampling. Our research target shifts from the "causality inference" to "correlativity analysis." This not only facilitates the evaluation of individualized treatment, disease prediction, prevention and prognosis, but also is suitable for the practice of preventive healthcare and symptom pattern differentiation for treatment in terms of traditional Chinese medicine (TCM), and for the post-marketing evaluation of Chinese patent medicines. To conduct clinical studies involved in big data in TCM domain, top level design is needed and should be performed orderly. The fundamental construction and innovation studies should be strengthened in the sections of data platform creation, data analysis technology and big-data professionals fostering and training. PMID:25217972

  18. In vitro anticancer activity of twelve Chinese medicinal herbs.

    Science.gov (United States)

    Shoemaker, Mark; Hamilton, Bobbi; Dairkee, Schanaz H; Cohen, Isaac; Campbell, Michael J

    2005-07-01

    Aqueous extracts of 12 Chinese medicinal herbs, Anemarrhena asphodeloides, Artemisia argyi, Commiphora myrrha, Duchesnea indica, Gleditsia sinensis, Ligustrum lucidum, Rheum palmatum, Rubia cordifolia, Salvia chinensis, Scutellaria barbata, Uncaria rhychophylla and Vaccaria segetalis were evaluated for their antiproliferative activity on eight cancer cell lines as well as on normal human mammary epithelial cells. Five human and three murine cancer cell lines representing different tissues (breast, lung, pancreas and prostate) were used. All the crude aqueous extracts demonstrated growth inhibitory activity on some or all of the cancer cell lines, but only two showed activity against the normal mammary epithelial cells. Overall, the murine cell lines tended to be more sensitive to most of the extracts compared with the human cell lines. Among the human cell lines, cell type specificity was observed for two extracts. These results indicate the potential use of traditional Chinese medicinal herbs as antineoplastic agents and suggest that further studies evaluating their mechanism(s) of action and the isolation of active antitumor compounds are warranted.

  19. SOME RARE HOMOEOPATHIC MEDICINAL PLANTS OF SOUTH INDIA

    OpenAIRE

    S.rajan

    1993-01-01

    This present study describes 11 species under 11 generate and 10 families of rare Homoeopathic Medicinal Plants introduced and cultivated in the Nilgiri district, Tamil Nadu, South India. The original citation, description, distribution and their medicinal uses are given.

  20. Antibacterial activity of five Peruvian medicinal plants against Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Gabriela Ulloa-Urizar

    2015-11-01

    Conclusions: The results of the present study scientifically validate the inhibitory capacity of the five medicinal plants attributed by their common use in folk medicine and contribute towards the development of new treatment options based on natural products.

  1. Volume, value and floristic diversity of Gabon's medicinal plant markets

    NARCIS (Netherlands)

    Towns, A.M.; Quiroz Villarreal, D.K.; Guinee, L.; Boer, H.; Andel, van T.

    2014-01-01

    Ethnopharmacological relevance - African medicinal plant markets offer insight into commercially important species, salient health concerns in the region, and possible conservation priorities. Still, little quantitative data is available on the trade in herbal medicine in Central Africa. The aim of

  2. Pharmacokinetic profile of phytoconstituent(s) isolated from medicinal plants-A comprehensive review.

    Science.gov (United States)

    Mehta, Piyush; Shah, Rishi; Lohidasan, Sathiyanarayanan; Mahadik, K R

    2015-10-01

    Herbal medicine, the backbone of traditional medicine, has played an important role in human health and welfare for a long period. Traditional therapeutic approaches of regional significance are found in Africa, South and Central America, China, India, Tibet, Indonesia, and the Pacific Islands. The considerable scientific significance and commercial potential of traditional medicines have resulted in increased international attention and global market demands for herbal medicines, especially Chinese herbal medicines. Herbal medicines currently are the primary form of health care for the poor in the developing countries, and also are widely used as a supplement or substitute for conventional drugs in developed countries. These traditional medicines have a pivotal role in the treatment of various ailments and more than 50% of drugs used in Western pharmacopoeia are isolated from herbs or derived from modifications of chemicals found in plants. Herbal medicines usually contain a complex mixture of various bioactive molecules, which make its standardization complicated, and there is little information about all compounds responsible for pharmacological activity. Several research papers have been published that claim pharmacological activity of herbal medicines but few are discussing the role of the exact phytoconstituent. Understanding the pharmacokinetic profile of such phytoconstituents is essential. Although there are research papers that deal with pharmacokinetic properties of phytoconstituents, there are a number of phytoconstituents yet to be explored for their kinetic properties. This article reviews the pharmacokinetic profile of 50 different therapeutically effective traditional medicinal plants from the year 2003 onward.

  3. [Fungi isolated from diseased medicinal plants].

    Science.gov (United States)

    Sato, T; Matsuhashi, M; Iida, O

    1992-01-01

    One hundred and forty-four fungal isolates were obtained from diseased Paeonia albiflora Pall. var. trichocarpa Bung., Astragalus membranaceus Bung., Lithospermum erythrorhizon Sieb. et Zucc., Ledebouriella seseloides Wolff and Bupleurum falcatum L. which were collected in the test field of Tsukuba Medicinal Plant Research Station, National Institute of Hygienic Sciences. Most of them were identified into 15 genera containing 8 species. Fungal species presumed to be pathogens of the host plants were as follows: Cladosporium paeoniae, Pestalotia paeoniicola, Glomerella cingulata, Hainesia lythri, Guignardia sp. and Alternaria sp. from P. albiflora, Fusarium spp., Rhizoctonia spp. and Neocosmospora vasinfecta from A. membranaceus, Colletotrichum gloeosporioides from L. erythrorhizon, Rhizoctonia sp., Fusarium spp., Phoma sp. and Pyrenochaeta sp. from L. seseloides, and Fusarium sp., Alternaria alternata, Phyllosticta sp., Phoma sp., Phomopsis sp. and C. gloeosporioides from B. falcatum. Roots of B. falcatum were found to be parasitized by Meloidogyne sp. PMID:1364438

  4. Multimedia-based Medicinal Plants Sustainability Management System

    CERN Document Server

    Omogbadegun, Zacchaeus; Ayo, Charles; Mbarika, Victor; Omoregbe, Nicholas; Otofia, Efe; Chieze, Frank

    2011-01-01

    Medicinal plants are increasingly recognized worldwide as an alternative source of efficacious and inexpensive medications to synthetic chemo-therapeutic compound. Rapid declining wild stocks of medicinal plants accompanied by adulteration and species substitutions reduce their efficacy, quality and safety. Consequently, the low accessibility to and non-affordability of orthodox medicine costs by rural dwellers to be healthy and economically productive further threaten their life expectancy. Finding comprehensive information on medicinal plants of conservation concern at a global level has been difficult. This has created a gap between computing technologies' promises and expectations in the healing process under complementary and alternative medicine. This paper presents the design and implementation of a Multimedia-based Medicinal Plants Sustainability Management System addressing these concerns. Medicinal plants' details for designing the system were collected through semi-structured interviews and databas...

  5. Radio protective effects of some medicinal plants

    International Nuclear Information System (INIS)

    Many plants are known to have beneficial therapeutic effects as noted in the traditional Indian system of medicine, Ayurveda and used since time immemorial for curing diseases. Even today, nearly 70% of the world's population is dependent on plants for handling their health related problems and plants have been utilized successfully for the treatment of free radical-mediated diseases in human such as Rheumatoid arthritis, Atherosclerosis, Cancer, Alzheimer's disease, Parkinson's disease, aging and several other conditions including inflammatory diseases. Plant extracts eliciting radio protective efficacy contain a plethora of compounds including antioxidants, immunostimulants, cell proliferation stimulators, anti-inflammatory and antimicrobial agent, some of which may act in isolation as well as in combination with other constituents from the same plants. Glycyrrhiza glabra, Allium sepa, Allium sativum, Aloe arborescens, Amaranthus paniculatus, Curcuma longa, Moringa olefera and Syzygium cumini are some important radio protective plants. Alium sativum has been reported to possess antioxidant antimicrobial, antitumor, antimutagenic and anti-inflammatory properties. Aloe arborescens acts as a cell proliferate, healer and allergy reducer. Amaranthus paniculatus is used for purifying blood and treating scrofulous sores. Curcuma longa is widely used in antitumor and antibacterial activities. Leaf extract of Moringa oleifera is significantly used in nervous debility and healing of wound. Chlorella is well known nutrient dense superfood that contains 60% protein, 18 amino acids (including all the essential amino acids), more than 20 vitamins and minerals. Chlorell has been used to treat cancer and also protect the body from the effects of cancer radiation treatment due to its chlorophyll in abundance level. However they have little attention for their radio protective as well as antioxidant. There is an urgent need to develop newer, more efficient and reliable bioassays

  6. Terminology Standardization in Chinese Medicine:The Perspective from UCLA Center for East-West Medicine(Ⅰ)

    Institute of Scientific and Technical Information of China (English)

    Ka-Kit Hui; Sonya Pritzker

    2007-01-01

    @@ INTRODUCTlON by Ka-kit Hui,M.D. Because we recognize the clinical,educational,and cultural importance of translation and terminology in Chinese medicine,we feel that it is imperative to understand the perspectives of all concerned parties.This article thus addresses the issue of terminology standardization in English language Chinese medical Publications from the Point of View of multiple stakeholders in this field at the UCLA Center for East-West Medicine.

  7. Preliminary phytochemical screening of some Indian Medicinal Plants

    OpenAIRE

    Doss, A.

    2009-01-01

    Alkaloids, tannins, saponins, steroid, terpenoid, flavonoids, phenolic compounds and cardie glycoside distribution in five medicinal plants belonging to different families were assessed and compared. The medicinal plants investigated were Asteracantha longifolia (L.) Nees, Psassiflora edulis Sims, Berberis tinctoria Lesch, Sphaeranthus indicus Linn, and Solanum trilobatum Linn. All the plants were found to contain Phenols, Cardiac glycosides, Steroids, Saponins and Tannin except for the absen...

  8. Cardiac protection of new compounds from scientific Chinese medicine (SCM)

    Institute of Scientific and Technical Information of China (English)

    ZHU Yi-zhun

    2008-01-01

    Objective Purification and Standardization of Chinese herbal extracts became a hot topic since last decade. Though traditional Chinese medicine (TCM) has been used as a mixture from several herbs for centuries, it has been drawn much attention for studying the standardized Chinese herbs using modern technology. Methods Recently, we compared purified Salvia miltiorrhiza extract (PSME) with angiotensin-converting enzyme inhibitor, Rarnipril, in in vitro experiments and also in vivo using animal model of myocardial infarction. Results PSME was found to have a significantly higher trolox equivalent antioxidant capacity which indicated a great capacity for scavenging free radicals. PSME could also prevent pyrogalto red bleaching and DNA damage. After 2 weeks treatment with PSME or Ramipril, survival rates of rats with experimental myocardial infarction were marginally increased (68.2% and 71.4%) compared with saline (61.5%). In another recent study, we evaluated the cardioprotective effects of PSME on myocardial ischemia/reperfusion injury in isolated rat hearts and in hypoxic vascular smooth muscle calls. We found that PSME treated hearts showed significant postischemic contractile function recovery (develop pressure recovered to 44.2±4.9 % versus 17.1±5.7 %, P<0.05; maximum contraction recovered to 57.2±5.9 % versus 15.1±6.3%, P<0. 001; maximum relaxation restored to 69.3±7.3% versus 15.4±6.3%, P<0.001 in PSME and control group respectively). Conclusions Significant elevated in end-diastolic pressure, which indicated LV stiffening in PSME hearts might be resulted by exceed dose of PSME used. Purified and standardized Chinese herb could provide an alternative regimen for the prevention of ischemic heart disease.

  9. Determining method and conditional factors of electrochemical fingerprint of Chinese traditional medicine

    Institute of Scientific and Technical Information of China (English)

    ZHANG TaiMing; LIANG YiZeng; YUAN Bin; DING Feng; ZHANG YaPeng; WEI ManQiong; CHEN Xu

    2007-01-01

    The thermodynamic systems and kinetic model suitable for the electrochemical token of the component throng in Chinese traditional medicines have been analyzed.It has been indicated that the damp oscillatory reactions in the non-equilibrium close system and open system without the supplement of dissipative substance have important significance for the throng token and analysis of chemical components in Chinese traditional medicines.Various factors influencing the electrochemical fingerprint, such as reactant species and their concentrations, electrode types, temperature, stir rate, the kind, dosage and granularity of Chinese traditional medicines, have amply been researched by the B-Z oscillatory reaction which used malonic acid as a main dissipative substance.In addition, the quantitative information about the chemical components in Chinese traditional medicines has been discussed in detail.The method and its conditions for determining the electrochemical fingerprint used in scientifically distinguishing and evaluating Chinese traditional medicines have successfully been put forward.

  10. [Construction and implementation of quality control index for clinical safety of Chinese medicine injection].

    Science.gov (United States)

    Jiang, Jun-jie; Xie, Yan-ming

    2015-12-01

    In order to ensure the authenticity and accuracy of traditional Chinese medicine injection safety monitoring data, Chinese medicine injection safety monitoring quality control indicators, including the monitoring center, monitoring personnel, hardware conditions, monitoring progress and the number of patients into the group, original documents and archives management, electronic data, adverse events, quality management were constructed. Its application in the creation of major new drugs technology major projects, 10 kinds of traditional Chinese medicine injections clinical safety monitoring quality control work, found the missing case surveillance, not reported adverse events, only reported adverse reactions, electronic data reporting lag, lack of level of efforts to control the problem, and corrected, the traditional Chinese medicine injection safety monitoring of quality control and quality assurance, and subsequent Chinese medicine safety monitoring quality control to provide the reference. PMID:27245020

  11. Cytotoxicity Potentials of Eleven Bangladeshi Medicinal Plants

    Directory of Open Access Journals (Sweden)

    Amina Khatun

    2014-01-01

    Full Text Available Various forms of cancer are rising all over the world, requiring newer therapy. The quest of anticancer drugs both from natural and synthetic sources is the demand of time. In this study, fourteen extracts of different parts of eleven Bangladeshi medicinal plants which have been traditionally used for the treatment of different types of carcinoma, tumor, leprosy, and diseases associated with cancer were evaluated for their cytotoxicity for the first time. Extraction was conceded using methanol. Phytochemical groups like reducing sugars, tannins, saponins, steroids, gums, flavonoids, and alkaloids were tested using standard chromogenic reagents. Plants were evaluated for cytotoxicity by brine shrimp lethality bioassay using Artemia salina comparing with standard anticancer drug vincristine sulphate. All the extracts showed potent to moderate cytotoxicity ranging from LC50 2 to 115 µg/mL. The highest toxicity was shown by Hygrophila spinosa seeds (LC50=2.93 µg/mL and the lowest by Litsea glutinosa leaves (LC50=114.71 µg/mL in comparison with standard vincristine sulphate (LC50=2.04 µg/mL. Among the plants, the plants traditionally used in different cancer and microbial treatments showed highest cytotoxicity. The results support their ethnomedicinal uses and require advanced investigation to elucidate responsible compounds as well as their mode of action.

  12. Cytotoxicity potentials of eleven Bangladeshi medicinal plants.

    Science.gov (United States)

    Khatun, Amina; Rahman, Mahmudur; Haque, Tania; Rahman, Md Mahfizur; Akter, Mahfuja; Akter, Subarna; Jhumur, Afrin

    2014-01-01

    Various forms of cancer are rising all over the world, requiring newer therapy. The quest of anticancer drugs both from natural and synthetic sources is the demand of time. In this study, fourteen extracts of different parts of eleven Bangladeshi medicinal plants which have been traditionally used for the treatment of different types of carcinoma, tumor, leprosy, and diseases associated with cancer were evaluated for their cytotoxicity for the first time. Extraction was conceded using methanol. Phytochemical groups like reducing sugars, tannins, saponins, steroids, gums, flavonoids, and alkaloids were tested using standard chromogenic reagents. Plants were evaluated for cytotoxicity by brine shrimp lethality bioassay using Artemia salina comparing with standard anticancer drug vincristine sulphate. All the extracts showed potent to moderate cytotoxicity ranging from LC50 2 to 115 µg/mL. The highest toxicity was shown by Hygrophila spinosa seeds (LC50 = 2.93 µg/mL) and the lowest by Litsea glutinosa leaves (LC50 = 114.71 µg/mL) in comparison with standard vincristine sulphate (LC50 = 2.04 µg/mL). Among the plants, the plants traditionally used in different cancer and microbial treatments showed highest cytotoxicity. The results support their ethnomedicinal uses and require advanced investigation to elucidate responsible compounds as well as their mode of action. PMID:25431796

  13. Some Plants used in Ayurvedic and Homoeopathic Medicine

    Directory of Open Access Journals (Sweden)

    R.P.Joshi

    2013-05-01

    Full Text Available Traditional medicines are used by about 60% of the world’s population. These are used for primary health care, not only in rural areas of developing nations but they are also used in the developed countries where modern medicine are pre dominantly used. In the western world the use of medicinal herbs is continuously growing, approximately 40% of the population is using herbs for medical illness due to increased incidences of adverse effects of allopathic medicine. There are about 45000 plant species in India, Eastern Himalayas, Western Ghats and Andman and Nicobar Islands are the hot spot for medicinal plants. Officially documented plants with medicinal potential are 3000 but traditional practitioner use more than 6000. Seventy percent of the population in the rural India is dependent on the ayurvedic system of medicine. Most of the drugs used in modern medicine and ancient Indian medicinal system are of plant origin. Beside plants many minerals, salts and animal products are used in Ayurvedic medicines. Homoeopathy originated in west, German physician Samuel Hanemann was the father of homoeopathy (1796, the homeopathic remedies are prepared by successive dilution followed by shaking forcefully. Homoeopathy uses animal, plant, mineral, and synthetic substances in its remedies. Arsenicum album (arsenic oxide, Natrum muriaticum (sodium chloride, opium (plant, and thyroidinum (thyroid hormone are some of the homoeopathic medicines extracted from different sources.

  14. Medicinal plants, traditional medicine, markets and management in far-west Nepal

    OpenAIRE

    Kunwar, Ripu M; Mahat, Laxmi; Acharya, Ram P; Bussmann, Rainer W

    2013-01-01

    Background Modern therapeutic medicine is historically based on indigenous therapies and ethnopharmacological uses, which have become recognized tools in the search for new sources of pharmaceuticals. Globalization of herbal medicine along with uncontrolled exploitative practices and lack of concerted conservation efforts, have pushed many of Nepal's medicinal plants to the verge of extinction. Sustainable utilization and management of medicinal plants, based on traditional knowledge, is ther...

  15. Harmonization of monographic standards is needed to ensure the quality of Chinese medicinal materials

    Directory of Open Access Journals (Sweden)

    Zhao Sandy

    2009-09-01

    Full Text Available Abstract This article provides an overview on the regulations of Chinese medicinal materials (CMMs in various countries and regions. Harmonization of CMM monographs would provide standards for the quality control of CMM products and play an important role in the modernization and globalization of Chinese medicine. A harmonized regulatory system would improve the quality of CMMs thereby ensuring the safety of the products and assisting Chinese medicine practitioners in their practice. The fast growing demand worldwide for traditional medicines calls for harmonized monographic standards to safeguard the safety and quality of CMM products.

  16. Natural Products from Chinese Medicines with Potential Benefits to Bone Health.

    Science.gov (United States)

    Che, Chun-Tao; Wong, Man Sau; Lam, Christopher Wai Kei

    2016-01-01

    Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass and microstructure, leading to reduced bone strength and increased risk of fracture. It is often associated with reduced quality of life and other medical complications. The disease is common in the aging population, particularly among postmenopausal women and patients who receive long-term steroidal therapy. Given the rapid growth of the aging population, increasing life expectancy, the prevalence of bone loss, and financial burden to the healthcare system and individuals, demand for new therapeutic agents and nutritional supplements for the management and promotion of bone health is pressing. With the advent of global interest in complementary and alternative medicine and natural products, Chinese medicine serves as a viable source to offer benefits for the improvement and maintenance of bone health. This review summarizes the scientific information obtained from recent literatures on the chemical ingredients of Chinese medicinal plants that have been reported to possess osteoprotective and related properties in cell-based and/or animal models. Some of these natural products (or their derivatives) may become promising leads for development into dietary supplements or therapeutic drugs. PMID:26927052

  17. Natural Products from Chinese Medicines with Potential Benefits to Bone Health

    Directory of Open Access Journals (Sweden)

    Chun-Tao Che

    2016-02-01

    Full Text Available Osteoporosis is a progressive, systemic bone disorder characterized by loss of bone mass and microstructure, leading to reduced bone strength and increased risk of fracture. It is often associated with reduced quality of life and other medical complications. The disease is common in the aging population, particularly among postmenopausal women and patients who receive long-term steroidal therapy. Given the rapid growth of the aging population, increasing life expectancy, the prevalence of bone loss, and financial burden to the healthcare system and individuals, demand for new therapeutic agents and nutritional supplements for the management and promotion of bone health is pressing. With the advent of global interest in complementary and alternative medicine and natural products, Chinese medicine serves as a viable source to offer benefits for the improvement and maintenance of bone health. This review summarizes the scientific information obtained from recent literatures on the chemical ingredients of Chinese medicinal plants that have been reported to possess osteoprotective and related properties in cell-based and/or animal models. Some of these natural products (or their derivatives may become promising leads for development into dietary supplements or therapeutic drugs.

  18. Initial Studies on Alkaloids from Lombok Medicinal Plants

    OpenAIRE

    John B. Bremner; Surya Hadi

    2001-01-01

    Initial investigation of medicinal plants from Lombok has resulted in the collection of 100 plant species predicted to have antimicrobial, including antimalarial, properties according to local medicinal uses. These plants represent 49 families and 80 genera; 23% of the plants tested positively for alkaloids. Among the plants testing positive, five have been selected for further investigation involving structure elucidation and antimicrobial testing on the extracted alkaloids. Initial work on ...

  19. Initial Studies on Alkaloids from Lombok Medicinal Plants

    Directory of Open Access Journals (Sweden)

    John B. Bremner

    2001-01-01

    Full Text Available Initial investigation of medicinal plants from Lombok has resulted in the collection of 100 plant species predicted to have antimicrobial, including antimalarial, properties according to local medicinal uses. These plants represent 49 families and 80 genera; 23% of the plants tested positively for alkaloids. Among the plants testing positive, five have been selected for further investigation involving structure elucidation and antimicrobial testing on the extracted alkaloids. Initial work on structural elucidation of some of the alkaloids is reported briefly.

  20. Rare Disease Drug Policy and Inheritance and Innovation of Traditional Chinese Medicine

    OpenAIRE

    Baxian Yi; Guangping Wang; Xiaoming Wu

    2014-01-01

    Traditional Chinese medicine is an important component of the health care system in Chinese medical treatment and public health. Rare disease drugs in difficult miscellaneous diseases in traditional Chinese medicine have similar characteristics with the rare disease drugs (orphan drugs) in European and American countries, which both are characterized by individualized medical treatment. The two are different in the development thought. Treatment of difficult miscellaneous diseases in the trad...

  1. Traditional home gardens: A preserve of medicinal plants

    OpenAIRE

    Sangeeta Bajpai; Sharma, A K; V.K. Kanungo

    2013-01-01

    Traditional home gardens have been described as man-managed ecosystems with high energy subsidy, complex structure, and multiple functions. These have been reported as treasure trove of a rich biodiversity of plant species including medicinal plants used for traditional home remedies of various ailments. A review of research work on the status of medicinal plants in traditional rural home gardens is presented with the objective to explore them as potential preservation site for medicinal plan...

  2. Comments on Nigel Wiseman's A Practical Dictionary of Chinese Medicine ( Ⅱ )-- On the Use of Western Medical Terms to Express the Concepts of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Mr. Wiseman believes that Western medical terms chosen as equivalents of Chinese medical terms should be the words known to all speakers and not requiring any specialist knowledge or instrumentation to understand or identify, and strictly technical Western medical terms should be avoided regardless of their conceptual conformity to the Chinese terms. Accordingly, many inappropriate Western medical terms are selected as English equivalents by the authors of the Dictionary, and on the other hand, many ready-made appropriate Western medical terms are replaced by loan English terms with the Chinese style of word formation.The experience gained in solving the problems of translating Western medical terms into Chinese when Western medicine was first introduced to China is helpful for translating Chinese medical terms into English. How-ever, the authors of the Dictionary adhere to their own opinions, ignoring others experience. The English terms thus created do not reflect the genuine meaning of the Chinese terms, but make the English glossary in chaos. The so-called true face of traditional Chinese revealed by such terms is merely the Chinese custom of word formation and metaphoric rhetoric. In other words, traditional Chinese medicine is not regarded as a system of medicine but merely some Oriental folklore.

  3. [Present situation and development strategies of Chinese medicine preparation in medical institutions].

    Science.gov (United States)

    Wang, Jie; Qiao, Xi-Yao; Lin, Fei

    2015-11-01

    As the actual clinical reflecting of transform Chinese medicine special curative effect, Chinese medicine preparation not only satisfies the need of hospital clinic, scientific research and teaching, but also plays an important role in deepening medical and health system reform, improving people's health level and contributing to the economic growth. However, some problems about administration and approval (tending to western medicine), contraction of the scale, lack of synchronization for clinic and scientific research, and the imbalance of regional development make Chinese medicine preparation move forwards slowly in contradiction. It has not only reduced the effectiveness of the Chinese medicine preparation in hospital clinic, but also brought bad effect on modernized development of Chinese medicine preparation. Research shows that main influencing factors of status quo of Chinese medicine preparation in medical institution include imperfect laws and regulations, high cost than income, and shortage of talents in preparation research. The analysis indicated that the necessary measures to break the contradiction, improve clinical effect of Chinese medicine, and promote the modernization development of Chinese drugs preparation were as follows: government and related departments should strengthen the supporting force in policy by adjusting the examination and approval policy, speeding up dispensing use, reforming pricing system, including into medicare reimbursement, integrating advantage resources and so on; medical institution should actively carry out research and development of traditional Chinese Medicine through drawing the traditional and modern essence, reserving professional talents, and developing characteristic preparation; companies cooperate with hospitals for complementary advantages, which can rapidly transform Chinese medicine preparation into clinical practice. PMID:27071242

  4. [Identification of ancient Chinese medicinal specimens preserved at Natural History Museum in London].

    Science.gov (United States)

    Zhao, Zhong-zhen; Zhao, Kai-cun; Brand, Eric

    2015-12-01

    On-site field investigation was conducted to authenticate a batch of ancient Chinese medicinal decoction pieces that have been preserved in a rare collection at the Natural History Museum in London. These treasured artifacts comprise a portion of the Sloane Collection, and the nearly one hundred Chinese medicinal specimens examined within provide an objective record of the real situation regarding the Chinese medicinal materials in commercial circulation three hundred years ago. The precious data from this collection pro-vides an extremely valuable reference for the research into the history of medicinal exchange between China and the West during the Age of Exploration, shedding light on the evolution and historical changes in the species used in Chinese medicine, as well as the history of medicinal processing and decoction pieces.

  5. [Analysis on prescription rules of treating senile dementia based on traditional Chinese medicine inheritance auxiliary systems].

    Science.gov (United States)

    Zong, Xin; Ji, Xu-Ming; Wei, Feng-Qin; Shi, Zuo-Rong

    2014-02-01

    This is designed to analyze and summarize medication rules for treating senile dementia with Chinese medicine in CNKI according to the traditional Chinese medicine (TCM) inheritance auxiliary system. Collect documents in CNKI that account treating senile dementia with Chinese formula; filter and establish a formula database, and then to search for medication rules on the TCM inheritance auxiliary system. It is filtered that 104 formulas are used for treating senile dementia screening treat senile dementia, involving 147 kinds of Chinese medicine. Tonic medicine are most frequently used, followed by the medicine of activating blood circulation and resuscitating; medicine pair most used is Ligusticum chuanxiong Hort-Acorus tatarinowii, accounting for 27.9% of all formula. And then 8 core pairs and 4 new formulas are evolved. Analysis on formulas for treating senile dementia filtered form CNKI by TCM inheritance auxiliary system shows prescription is mainly tonifying, activating blood circulation and resuscitating, that reveals prescription rules, to provide a reference for clinical treatment.

  6. Progresses in Applications of Stable Isotope Technology to Determining Geographical Origins of Traditional Chinese Medicines

    Directory of Open Access Journals (Sweden)

    WANG Li-ming

    2015-11-01

    Full Text Available Identification of proper geographical origin of traditional Chinese medicine is critical for guaranteeing the quality and efficacy of the medicine, safeguarding the market order, and reducing the medical negligence rate due to fake products. Stable isotope technology, as one of the most efficient methods to determine agricultural products authenticity and traceability, have great advantages and theoretical basis for determining geo-origin of traditional Chinese medicine, and it has been applied to many expensive herbs. In this review, the basic principles of isotopic traceability were firstly introduced. We then elaborate in details the frequently-used isotopic indicators in the geo origin studies of traditional Chinese medicine. We also provide a summary of current research progresses and point out some directions for future research. The purpose of this paper is to promote the applications of stable isotopes to traditional Chinese medicine traceability studies and the establishment of the isotopic database and the improvement of the medicine traceability.

  7. Using the Theory of Planned Behaviour to Explain Use of Traditional Chinese Medicine among Hong Kong Chinese in Britain

    OpenAIRE

    Tina L. Rochelle; Shardlow, Steven M.; Sik Hung Ng

    2015-01-01

    The UK Chinese are known for their underutilisation of western healthcare services. Reasons for this underutilisation are complex. The Theory of Planned Behaviour (TPB) is a widely used model of social cognition, which in the present study is being applied to traditional Chinese medicine (TCM) utilisation and satisfaction with TCM services. Two hundred and seventy-two UK Chinese aged between 15 and 91 years (M = 46.55; SD = 18.53) enrolled in the study. TCM utilisation was associated with gen...

  8. Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Xuanbin Wang

    2014-01-01

    Full Text Available Chinese medicines have long history in treating cancer. With the growing scientific evidence of biomedical researches and clinical trials in cancer therapy, they are increasingly accepted as a complementary and alternative treatment. One of the mechanisms is to induce cancer cell death. Aim. To comprehensively review the publications concerning cancer cell death induced by Chinese medicines in recent years and provide insights on anticancer drug discovery from Chinese medicines. Materials and Methods. Chinese medicines (including Chinese medicinal herbs, animal parts, and minerals were used in the study. The key words including “cancer”, “cell death”, “apoptosis”, “autophagy,” “necrosis,” and “Chinese medicine” were used in retrieval of related information from PubMed and other databases. Results. The cell death induced by Chinese medicines is described as apoptotic, autophagic, or necrotic cell death and other types with an emphasis on their mechanisms of anticancer action. The relationship among different types of cell death induced by Chinese medicines is critically reviewed and discussed. Conclusions. This review summarizes that CMs treatment could induce multiple pathways leading to cancer cell death, in which apoptosis is the dominant type. To apply these preclinical researches to clinic application will be a key issue in the future.

  9. Research progress of traditional Chinese medicine treatment of diabeticnephropathy

    Institute of Scientific and Technical Information of China (English)

    Xiaoming Wu; Na Zhang; Yanbin Gao

    2014-01-01

    Diabetic nephropathy is the main reason of the end-stage renal failure and endanger human health seriously.Ef-fective treatment of diabetic nephropathy is in an urgent demand.In recent years,we confirmed the good effect of TCM on dia-betic nephropathy by evidence based medicine method.We also explored the treatment mechanism of TCM on diabetic ne-phropathy from overall level,cellular level and molecular level and found that both single herb and Chinese herbal compound can treat diabetic nephropathy by multiple targets control.TCM may become one of the effective methods for treating diabetic ne-phropathy.This paper will review the advances in this research field of recent years and provide references for future researches.

  10. Medicinal protection with Chinese herb-compound against radiation damage

    International Nuclear Information System (INIS)

    Experiments were carried out on mice and the subjects irradiated for cancer therapy to evaluate the protective efficacy of a Chinese medicinal herb-compound (CMHC). The lethality and the degree of leucopenia caused by radiation in mice medicated with CMHC were significantly less in comparison with control mice (p less than 0.01 and p less than 0.001, respectively). CMHC significantly improved the WBC and the thrombocytes in irradiated workers (p less than 0.01 and p less than 0.001, respectively). The WBC count of 40 patients under radiotherapy while treated with CMHC recovered from 3450 +/- 77/c.mm to 5425 +/- 264/c.mm (p less than 0.001); whereas, in the control group, without any medication, the WBC count dropped significantly (p less than 0.001). Our results revealed the applicabilities of CMHC in protection against radiation damage in spaceflight and in other fields

  11. Medicinal protection with Chinese herb-compound against radiation damage

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, R.J.; Qian, J.K.; Yang, G.H.; Wang, B.Z.; Wen, X.L. (Institute of Space Medico-Engineering, Beijing (China))

    1990-08-01

    Experiments were carried out on mice and the subjects irradiated for cancer therapy to evaluate the protective efficacy of a Chinese medicinal herb-compound (CMHC). The lethality and the degree of leucopenia caused by radiation in mice medicated with CMHC were significantly less in comparison with control mice (p less than 0.01 and p less than 0.001, respectively). CMHC significantly improved the WBC and the thrombocytes in irradiated workers (p less than 0.01 and p less than 0.001, respectively). The WBC count of 40 patients under radiotherapy while treated with CMHC recovered from 3450 +/- 77/c.mm to 5425 +/- 264/c.mm (p less than 0.001); whereas, in the control group, without any medication, the WBC count dropped significantly (p less than 0.001). Our results revealed the applicabilities of CMHC in protection against radiation damage in spaceflight and in other fields.

  12. Novel PDE4 inhibitors derived from Chinese medicine forsythia.

    Directory of Open Access Journals (Sweden)

    Tiffany A Coon

    Full Text Available Cyclic adenosine monophosphate (cAMP is a crucial intracellular second messenger molecule that converts extracellular molecules to intracellular signal transduction pathways generating cell- and stimulus-specific effects. Importantly, specific phosphodiesterase (PDE subtypes control the amplitude and duration of cAMP-induced physiological processes and are therefore a prominent pharmacological target currently used in a variety of fields. Here we tested the extracts from traditional Chinese medicine, Forsythia suspense seeds, which have been used for more than 2000 years to relieve respiratory symptoms. Using structural-functional analysis we found its major lignin, Forsynthin, acted as an immunosuppressant by inhibiting PDE4 in inflammatory and immune cell. Moreover, several novel, selective small molecule derivatives of Forsythin were tested in vitro and in murine models of viral and bacterial pneumonia, sepsis and cytokine-driven systemic inflammation. Thus, pharmacological targeting of PDE4 may be a promising strategy for immune-related disorders characterized by amplified host inflammatory response.

  13. Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

    Science.gov (United States)

    Coon, Tiffany A.; McKelvey, Alison C.; Weathington, Nate M.; Birru, Rahel L.; Lear, Travis; Leikauf, George D.; Chen, Bill B.

    2014-01-01

    Cyclic adenosine monophosphate (cAMP) is a crucial intracellular second messenger molecule that converts extracellular molecules to intracellular signal transduction pathways generating cell- and stimulus-specific effects. Importantly, specific phosphodiesterase (PDE) subtypes control the amplitude and duration of cAMP-induced physiological processes and are therefore a prominent pharmacological target currently used in a variety of fields. Here we tested the extracts from traditional Chinese medicine, Forsythia suspense seeds, which have been used for more than 2000 years to relieve respiratory symptoms. Using structural-functional analysis we found its major lignin, Forsynthin, acted as an immunosuppressant by inhibiting PDE4 in inflammatory and immune cell. Moreover, several novel, selective small molecule derivatives of Forsythin were tested in vitro and in murine models of viral and bacterial pneumonia, sepsis and cytokine-driven systemic inflammation. Thus, pharmacological targeting of PDE4 may be a promising strategy for immune-related disorders characterized by amplified host inflammatory response. PMID:25549252

  14. Prevention and Treatment of Osteoporosis with Chinese Herbal Medicines

    Institute of Scientific and Technical Information of China (English)

    ZHAO Xiao-ling; FENG Yu-xiong; PENG Yong

    2012-01-01

    In this paper,laboratory reports,medication rules,formulating principles,and research methods are summarized and analyzed,including single herb,compound herbs,and the problems in the prevention and treatment of osteoporosis(OP)within the past decade.With widely recognized efficacy,satisfying achievements have been achieved in preventing and treating OP with Chinese herbal medicines(CHM).However,due to the complex constituents,the pharmacological activities and mechanism of CHM are not clear yet,and there is no unified standard on the diagnosis and syndrome differentiation of OP and the efficacy evaluation of CHM in the treatment.Accordingly,the research in the future should focus on the pharmacology and standardization of CHM in treating OP.

  15. Research advances in traditional Chinese medicine syndromes in cancer patients.

    Science.gov (United States)

    Ji, Qing; Luo, Yun-quan; Wang, Wen-hai; Liu, Xuan; Li, Qi; Su, Shi-bing

    2016-01-01

    Traditional Chinese medicine (TCM) syndrome, also known as TCM ZHENG or TCM pattern, is an integral and essential part of TCM theory that helps to guide the design of individualized treatments. A TCM syndrome, in essence, is a characteristic profile of all clinical manifestations in one patient that can be readily identified by a TCM practitioner. In this article, the authors reviewed the presentations of TCM syndromes in seven common malignancies (liver, lung, gastric, breast, colorectal, pancreatic and esophageal cancers), the objectivity and the standardization of TCM syndrome differentiation, the evaluation of TCM syndrome modeling in cancer research, and syndrome differentiation-guided TCM treatment of cancers. A better understanding of TCM syndrome theory, as well as its potential biological basis, may contribute greatly to the clinical TCM diagnosis and the treatment of cancer.

  16. Functional Somatic Syndromes: Emerging Biomedical Models and Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Steven Tan

    2004-01-01

    Full Text Available The so-called functional somatic syndromes comprise a group of disorders that are primarily symptom-based, multisystemic in presentation and probably involve alterations in mind-brain-body interactions. The emerging neurobiological models of allostasis/allostatic load and of the emotional motor system show striking similarities with concepts used by Traditional Chinese Medicine (TCM to understand the functional somatic disorders and their underlying pathogenesis. These models incorporate a macroscopic perspective, accounting for the toll of acute and chronic traumas, physical and emotional stressors and the complex interactions between the mind, brain and body. The convergence of these biomedical models with the ancient paradigm of TCM may provide a new insight into scientifically verifiable diagnostic and therapeutic approaches for these common disorders.

  17. Systems biology-based diagnostic principles as pillars of the bridge between Chinese and Western medicine

    NARCIS (Netherlands)

    Greef, J. van der; Wietmarschen, H. van; Schroën, J.; Wang, M.; Hankemeier, T.; Xu, G.

    2010-01-01

    Innovative systems approaches to develop medicine and health care are emerging from the integration of Chinese and Western medicine strategies, philosophies and practices. The two medical systems are highly complementary as the reductionist aspects of Western medicine are favourable in acute disease

  18. Chinese herbal medicine and acupuncture for the treatment of cardiovascular disease

    Institute of Scientific and Technical Information of China (English)

    Jun Xu; Haiyun Wu

    2009-01-01

    @@ Traditional Chinese medicine (TCM) is one of the world's oldest healing systems. TCM includes herbal medicine, acupuncture, moxibustion, massage, food therapy, and physical exercise, such as shadow boxing. In modern China, TCM is a fully institutionalised part of health care and widely used with Western medicine.

  19. Color and Edge Histograms Based Medicinal Plants' Image Retrieval

    Directory of Open Access Journals (Sweden)

    Basavaraj S. Anami

    2012-08-01

    Full Text Available In this paper, we propose a methodology for color and edge histogram based medicinal plants image retrieval. The medicinal plants are divided into herbs, shrubs and trees. The medicinal plants are used in ayurvedic medicines. Manual identification of medicinal plants requires a priori knowledge. Automatic recognition of medicinal plants is useful. We have considered medicinal plant species, such as Papaya, Neem, Tulasi and Aloevera are considered for identification and retrieval. The color histograms are obtained in RGB, HSV and YCbCr color spaces. The number of valleys and peaks in the color histograms are used as features. But, these features alone are not helpful in discriminating plant images, since majority plant images are green in color. We have used edge and edge direction histograms in the work to get edges in the stem and leafy parts. Finally, these features are used in retrieval of medicinal plant images. Absolute distance, Euclidean distance and mean square error, similarity distance measures are deployed in the work. The results show an average retrieval efficiency of 94% and 98% for edge and edge direction features respectively.

  20. 中药名与中医药文化%Traditional Chinese Medicine Name and Chinese Medical Culture

    Institute of Scientific and Technical Information of China (English)

    何明举

    2014-01-01

    Traditional Chinese medicine name is the carrier of culture of Chinese medicine,the crystallization of marriage of Chinese medicine and cultural art,which contains rich thoughts of humanities and philosophy. Since ancient times,it has spread more,and is a unique cultural landscape in the history of Chinese,it is precious wealth conceived of the development of Chinese medicine business by people,which has shown the cultural characteristics of traditional Chinese medicine incisively and vividly.%中药名是中医药文化的载体,是中医药与文化艺术联姻的结晶,蕴含着丰富的人文科学和哲学思想。自古多有流传,可谓华夏史上一道奇特的文化景观,是人民在千百年的中医药事业奋斗发展中孕育出来的宝贵财富,把中医学的文化特色彰显得淋漓尽致。

  1. [Data integration, data mining and visualization analysis of traditional Chinese medicine manufacturing process].

    Science.gov (United States)

    Li, Zheng; Kang, Li-Yuan; Fan, Xiao-Hui

    2014-08-01

    Huge amount of data becomes available from the pharmaceutical manufacturing process with wide application of in- dustrial automatic control technology in traditional Chinese medicine (TCM) industry. The industrial big data thus provides golden op- portunities to better understand the manufacturing process and improve the process performance. Therefore it is important to implement data integration and management systems in TCM plants to easily collect, integrate, store, analyze, communicate and visulize the data with high efficiency. It could break the data island and discover useful information and knowledge to improve the manufacturing process performance. The key supporting technologies for TCM manufacturing and industrial big data management were introduced in this paper, with a specific focus on data mining and visualization technologies. Using historic data collected from a manufacturing plant of Shengmai injection of SZYY group, we illustrated the usefulness and discussed future prospects of data mining and visualization technologies. PMID:25507568

  2. STUDY OF DRUG LIKENESS ACTIVITY OF PHYTOCHEMICALS IN MEDICINAL PLANTS

    OpenAIRE

    V. Sathya; Gopalakrishnan, V. K.

    2012-01-01

    Phytochemicals in medicinal plants can deliver potential therapeutic drugs such as anticancer, antiviral, antioxidant etc. The plant kingdom is a treasure house of potential drugs and each phytochemical cannot be tested in the wetlab preparations. Hence the main aim of the study is the drug likeness activity of phytochemicals in medicinal plants such as Anethum graveolens, Apium graveolens against hepatocellular carcinoma. These plants have anticancer, antilivercancer, hepatoprotective, antiv...

  3. 2种中药植物提取物抑菌活性初步研究%Preliminary Studies on Antifungal Activity of Two Chinese Herbal Medicinal Plant Extracts

    Institute of Scientific and Technical Information of China (English)

    钟慧; 钟勇; 卿朕; 周秋艳; 邓业成

    2015-01-01

    采用生长速率法测定苍术和乌药2种中药植物甲醇提取物对10种植物病原真菌的抑菌活性,为其在农药领域的开发利用提供依据。结果表明,苍术甲醇提取物对玉米大斑病菌、金橘砂皮病菌、甘蔗凤梨病菌、茶轮斑病菌、烟草黑胫病菌有很高的抑菌活性,质量浓度为10 g/L时,抑菌率在85.17%~100%,其对玉米大斑病菌、甘蔗凤梨病菌、茶轮斑病菌、水稻胡麻叶斑病菌、辣椒炭疽病菌、烟草黑胫病菌菌丝的有效中浓度( EC50值)为0.1316~0.9802 g/L。乌药甲醇提取物对10种植物病原真菌均有很高的抑菌活性,质量浓度为10 g/L时,抑菌率均在80%以上,其中对除贡柑链格孢菌外9种植物病原真菌菌丝的EC50值为0.1020~0.6329 g/L。采用液-液萃取法和固-液萃取法分别对苍术和乌药的抑菌活性成分进行初步分离,结合活性跟踪,发现苍术抑菌活性成分主要存在于乙酸乙酯萃取层和石油醚萃取层中,乌药抑菌活性成分主要存在于乙酸乙酯萃取层中。%A growth rate method was used for determining the antifungal activity of methanol extracts from two species of Chinese herbal medicine against ten species of plant pathogenic fungi.The results showed that the methanol extract from Atractylodes lancea ( Thunb.) DC.had a high inhibitory activity against Exserohilum turcicum ( Pass ) Leonard et Suggs, Diaporthe citri ( Fawcett ) Wolf, Ceratocystis paradoxa (Dode)Moreau,Pestalotiopsis theae(Sawada)Steyaert,Phytophthora parasitica var.Nicotianae(Breda de Hean)Tucker,with the inhibition rates of 85.17%—100%at 10 g/L.EC50 values of the methanol extract from Atractylodes lancea(Thunb.)DC.against Exserohilum turcicum(Pass)Leonard et Suggs,Ceratocystis paradoxa(Dode)Moreau,Pestalotiopsis theae(Sawada)Steyaert,Cochliobolus miyabeanus(Ito et Kubibay) Drechsler et Dastur,Colletotrichum capsici( syd.) Butl

  4. [Sample size calculation in clinical post-marketing evaluation of traditional Chinese medicine].

    Science.gov (United States)

    Fu, Yingkun; Xie, Yanming

    2011-10-01

    In recent years, as the Chinese government and people pay more attention on the post-marketing research of Chinese Medicine, part of traditional Chinese medicine breed has or is about to begin after the listing of post-marketing evaluation study. In the post-marketing evaluation design, sample size calculation plays a decisive role. It not only ensures the accuracy and reliability of post-marketing evaluation. but also assures that the intended trials will have a desired power for correctly detecting a clinically meaningful difference of different medicine under study if such a difference truly exists. Up to now, there is no systemic method of sample size calculation in view of the traditional Chinese medicine. In this paper, according to the basic method of sample size calculation and the characteristic of the traditional Chinese medicine clinical evaluation, the sample size calculation methods of the Chinese medicine efficacy and safety are discussed respectively. We hope the paper would be beneficial to medical researchers, and pharmaceutical scientists who are engaged in the areas of Chinese medicine research. PMID:22292397

  5. Natural occurrence of mycotoxins in medicinal plants: a review.

    Science.gov (United States)

    Ashiq, Samina; Hussain, Mubbashir; Ahmad, Bashir

    2014-05-01

    Medicinal plants are widely used as home remedies and raw materials for the pharmaceutical industries. Herbal remedies are used in the prevention, treatment and cure of disorders and diseases since ancient times. However, use of medicinal herbs may not meet the requirements of quality, safety and efficacy. During harvesting, handling, storage and distribution, medicinal plants are subjected to contamination by various fungi, which may be responsible for spoilage and production of mycotoxins. The increasing consumption of medicinal plants has made their use a public health problem due to the lack of effective surveillance of the use, efficacy, toxicity and quality of these natural products. The increase in use of medicinal plants may lead to an increase in the intake of mycotoxins therefore contamination of medicinal plants with mycotoxins can contribute to adverse human health problems and therefore represents a special hazard. Numerous natural occurrences of mycotoxins in medicinal plants and traditional herbal medicines have been reported from various countries including Spain, China, Germany, India, Turkey and from Middle East as well. This review discusses the important mycotoxins and their natural occurrences in medicinal plants and their products. PMID:24594211

  6. Natural occurrence of mycotoxins in medicinal plants: a review.

    Science.gov (United States)

    Ashiq, Samina; Hussain, Mubbashir; Ahmad, Bashir

    2014-05-01

    Medicinal plants are widely used as home remedies and raw materials for the pharmaceutical industries. Herbal remedies are used in the prevention, treatment and cure of disorders and diseases since ancient times. However, use of medicinal herbs may not meet the requirements of quality, safety and efficacy. During harvesting, handling, storage and distribution, medicinal plants are subjected to contamination by various fungi, which may be responsible for spoilage and production of mycotoxins. The increasing consumption of medicinal plants has made their use a public health problem due to the lack of effective surveillance of the use, efficacy, toxicity and quality of these natural products. The increase in use of medicinal plants may lead to an increase in the intake of mycotoxins therefore contamination of medicinal plants with mycotoxins can contribute to adverse human health problems and therefore represents a special hazard. Numerous natural occurrences of mycotoxins in medicinal plants and traditional herbal medicines have been reported from various countries including Spain, China, Germany, India, Turkey and from Middle East as well. This review discusses the important mycotoxins and their natural occurrences in medicinal plants and their products.

  7. Anti-fibro-hepatocarcinogenic Chinese herbal medicines: A mechanistic overview.

    Science.gov (United States)

    Boye, Alex; Yang, Yan; Asenso, James; Wei, Wei

    2016-01-01

    Chinese herbal medicine (CHM) is an integral component of complementary/alternative medicine and it is increasingly becoming the preferred therapeutic modality for the treatment of liver fibrosis and hepatocellular carcinoma (HCC) worldwide. Accordingly, the World Health Organization (WHO) has attested to the popularity and efficacy of indigenous herbal therapies including CHM as a first line of treatment for some diseases including liver disorders. However, the WHO and drug discovery experts have always recommended that use of indigenous herbal remedies must go hand-in-hand with the requisite mechanistic elucidation so as to constitute a system of verification of efficacy within the ethnobotanical context of use. Although many CHM experts have advanced knowledge on CHM, nonetheless, more enlightenment is needed, particularly mechanisms of action of CHMs on fibro-hepato-carcinogenesis. We, herein, provide in-depth mechanisms of the action of CHMs which have demonstrated anti-fibro-hepatocarcinogenic effects, in pre-clinical and clinical studies as published in PubMed and other major scientific databases. Specifically, the review brings out the important signaling pathways, and their downstream targets which are modulated at multi-level by various anti-fibro-hepatocarcinogenic CHMs. PMID:27366355

  8. Publishing Chinese medicine knowledge as Linked Data on the Web

    Directory of Open Access Journals (Sweden)

    Zhao Jun

    2010-07-01

    Full Text Available Abstract Background Chinese medicine (CM draws growing attention from Western healthcare practitioners and patients. However, the integration of CM knowledge and Western medicine (WM has been hindered by a barrier of languages and cultures as well as a lack of scientific evidence for CM's efficacy and safety. In addition, most of CM knowledge published with relational database technology makes the integration of databases even more challenging. Methods Linked Data approach was used in publishing CM knowledge. This approach was applied to publishing a CM linked dataset, namely RDF-TCM http://www.open-biomed.org.uk/rdf-tcm/ based on TCMGeneDIT, which provided association information about CM in English. Results The Linked Data approach made CM knowledge accessible through standards-compliant interfaces to facilitate the bridging of CM and WM. The open and programmatically-accessible RDF-TCM facilitated the creation of new data mash-up and novel federated query applications. Conclusion Publishing CM knowledge in Linked Data provides a point of departure for integration of CM databases.

  9. Anti-fibro-hepatocarcinogenic Chinese herbal medicines: A mechanistic overview

    Science.gov (United States)

    Boye, Alex; Yang, Yan; Asenso, James; Wei, Wei

    2016-01-01

    Chinese herbal medicine (CHM) is an integral component of complementary/alternative medicine and it is increasingly becoming the preferred therapeutic modality for the treatment of liver fibrosis and hepatocellular carcinoma (HCC) worldwide. Accordingly, the World Health Organization (WHO) has attested to the popularity and efficacy of indigenous herbal therapies including CHM as a first line of treatment for some diseases including liver disorders. However, the WHO and drug discovery experts have always recommended that use of indigenous herbal remedies must go hand-in-hand with the requisite mechanistic elucidation so as to constitute a system of verification of efficacy within the ethnobotanical context of use. Although many CHM experts have advanced knowledge on CHM, nonetheless, more enlightenment is needed, particularly mechanisms of action of CHMs on fibro-hepato-carcinogenesis. We, herein, provide in-depth mechanisms of the action of CHMs which have demonstrated anti-fibro-hepatocarcinogenic effects, in pre-clinical and clinical studies as published in PubMed and other major scientific databases. Specifically, the review brings out the important signaling pathways, and their downstream targets which are modulated at multi-level by various anti-fibro-hepatocarcinogenic CHMs. PMID:27366355

  10. Management of SAH with traditional Chinese medicine in China.

    Science.gov (United States)

    Wang, Chunxue; Zhao, Xingquan; Mao, Shujing; Wang, Yongjun; Cui, Xiangning; Pu, Yuehua

    2006-06-01

    China lacks large scale authorized epidemiological study results in allusion to subarachnoid hemorrhage (SAH) within recent 15 years since MONICA (multinational monitoring of trends and determinants in cardiovascular disease) study revealed SAH situation in China in 2000. The main cause of SAH in China is aneurysm which takes up 30-50%, while over 90% aneurysm locates at Willis circle. Early surgery for SAH after aneurysm rupture is the dominant procedure to deal with SAH in China. Moreover, calcium antagonists rank the absolute leading position for cerebral vascular spasm (CVS) among medication-based treatment options. However, traditional Chinese medicine such as Salvia miltiorrhiza, Acanthopanax senticosus, Ginkgo biloba, Pueraria lobata, Liguisticum chuanxiong, cow bezoar, Diospyros kaki and Gynostemma pentaphyllum have been proven beneficial in CVS prevention and treatment, while Salvia miltiorrhiza and TCM soup have unique effects on bleeding absorption. In addition, aescine and some TCM soup might relieve strong headache after SAH. In general, TCM integrated with western medicine have shown unique advantages in the current treatment of SAH in China. However, it is a pity that China still lacks larger scale randomized controlled trials and research on SAH treatment focusing on TCM and the related mechanism of TCM on SAH still need to be investigated further.

  11. Anticancer effects of Chinese herbal medicine, science or myth?

    Institute of Scientific and Technical Information of China (English)

    RUAN Wen-jing; LAI Mao-de; ZHOU Jian-guang

    2006-01-01

    Currently there is considerable interest among oncologists to find anticancer drugs in Chinese herbal medicine (CHM).In the past, clinical data showed that some herbs possessed anticancer properties, but western scientists have doubted the scientific validity of CHM due to the lack of scientific evidence from their perspective. Recently there have been encouraging results, from a western perspective, in the cancer research field regarding the anticancer effects of CHM. Experiments showed that CHM played its anticancer role by inducing apoptosis and differentiation, enhancing the immune system, inhibiting angiogenesis, reversing multidrug resistance (MDR), etc. Clinical trials demonstrated that CHM could improve survival, increase tumor response, improve quality of life, or reduce chemotherapy toxicity, although much remained to be determined regarding the objective effects of CHM in human in the context of clinical trials. Interestingly, both laboratory experiments and clinical trials have demonstrated that when combined with chemotherapy, CHM could raise the efficacy level and lower toxic reactions. These facts raised the feasibility of the combination of herbal medicines and chemotherapy, although much remained to be investigated in this area.

  12. Inhibition of Urogenital Chlamydia Trachomatis in Vitro by 12 Diuretic Traditional Chinese Medicines

    Institute of Scientific and Technical Information of China (English)

    LI Jianjun(李建军); TU Yuying(涂裕英); TONG Juzhen(佟菊贞); WANG Peitu(汪培土)

    2002-01-01

    Objective:To detect the inhibition of urogenital chlamydia trachomatis (CT) by 12 traditional Chinese medicines in vitro.Methods: The inhibition of CT isolates by these medicines was detected by micro-culture technique with McCoy cells in vitro.Results: All the diuretic traditional Chinese medicines inhibited urogenital CT. The minimum inhibitory concentrations (MICs) ranged from 0.122 mg ml-1 to 62.5 mg ml-1. Diathus superbus L., Poria cocos (Shcw.) Woft,Polyporus umbellatus (Pets.) Fries, and Artemisia capillaries Thunb showed stronger inhibition than the other eight traditional Chinese medicines. The numbers and sizes of inclusions bodies reduced gradually and disappeared finally with the increase of the concentrations.Conclusion: All the 12 diuretic traditional Chinese medicines inhibited urogenital CT.

  13. Effect of Chinese Herbal Medicine on Immunohistochemistry of Harder's Glands of Chickens

    Institute of Scientific and Technical Information of China (English)

    SHEN Ping; GAO Guisheng; SHI Qiumei; LI Min

    2009-01-01

    To investigate the mechanism of action of Chinese herbal medicine, the immunocells of Harder's glands were observed.The healthy Hy-Line Brown chickens of 12-day-old were divided into three groups randomly. The chickens in group 1 and 2 drank the water with 0.5% and 1% Chinese herbal medicine immunopromoter every day. The chickens in group 3 as control drank pure water. The Harder's glands of the chickens from 0.5% group, 1% group and control group at 24, 36 and 48 d after drinking medicine respectively were made into histological section. And then the histological sections were observed histologically. The results showed that Chinese herbal medicine could increase the quantity of the immunocells in glandular organs conspicuously. Immunopotentiator of Chinese herbal medicine could promote the amount and growth of secreted immunoglobuline and elevate the immune level of the organism, and the effect of 1% group was higher than that of 0.5% group.

  14. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital.

    Science.gov (United States)

    Lao, Lixing; Ning, Zhipeng

    2015-11-01

    The European Congress for Integrative Medicine 2015 Global Summit on Integrative Medicine and Healthcare in Greater Copenhagen has successfully promoted integrative medicine to the public once again. Integrative medicine, which is called the art and science of healthcare by Nordic Integrative Medicine, has been widely used in the world. In Hong Kong, integrated traditional Chinese and Western medicine, which is also known as the Chinese version of integrative medicine, provides a valuable reference for the development of integrative medicine in the world. In this article, we introduce the development of traditional Chinese medicine in Hong Kong and an integrated traditional Chinese and Western medicine model in the University of Hong Kong-Shenzhen Hospital.

  15. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital.

    Science.gov (United States)

    Lao, Lixing; Ning, Zhipeng

    2015-11-01

    The European Congress for Integrative Medicine 2015 Global Summit on Integrative Medicine and Healthcare in Greater Copenhagen has successfully promoted integrative medicine to the public once again. Integrative medicine, which is called the art and science of healthcare by Nordic Integrative Medicine, has been widely used in the world. In Hong Kong, integrated traditional Chinese and Western medicine, which is also known as the Chinese version of integrative medicine, provides a valuable reference for the development of integrative medicine in the world. In this article, we introduce the development of traditional Chinese medicine in Hong Kong and an integrated traditional Chinese and Western medicine model in the University of Hong Kong-Shenzhen Hospital. PMID:26559359

  16. Integrating traditional Chinese medicine into mainstream healthcare system in Hong Kong, China-A model of integrative medicine in the HKU-SZ Hospital

    Institute of Scientific and Technical Information of China (English)

    Lixing Lao; Zhipeng Ning

    2015-01-01

    The European Congress for Integrative Medicine 2015 Global Summit on Integrative Medicine and Healthcare in Greater Copenhagen has successfully promoted integrative medicine to the public once again. Integrative medicine, which is called the art and science of healthcare by Nordic Integrative Medicine, has been widely used in the world. In Hong Kong, integrated traditional Chinese and Western medicine, which is also known as the Chinese version of integrative medicine, provides a valuable reference for the development of integrative medicine in the world. In this article, we introduce the development of traditional Chinese medicine in Hong Kong and an integrated traditional Chinese and Western medicine model in the University of Hong Kong-Shenzhen Hospital.

  17. Stability in Effects of gamma-Irradiated Chinese Medicinal Prescriptions on Protection of Mice from Radiation

    International Nuclear Information System (INIS)

    The radioprotective effects of irradiated medicinal plants on biological system were studied to apply the irradiation technology for hygienic purpose that is usually performed by chemical preservatives. We previously reported that the three Chinese medicinal prescriptions, Si-Wu-Tang, Bu-Zhong-Yi-Qi-Tang and San-Ling-Bai-Shu-San, showed radioprotective effects in mice. In these experiments, to investigate the difference in radioprotective effects between irradiated (10 kGy) and non-irradiated medicinal plants, mice were administered with the irradiated or non-irradiated prescriptions and then the mice were exposed to gamma-rays with low and high dosage. Non-exposed mice were also prepared as a control. The effects of prescriptions on the jejunal crypt survival, endogenous spleen colony formation, and apoptosis of jejunal crypt cells in mice were investigated after exposure. All of the prescriptions showed the protective effects of the jejunal crypt (p0.05) and the adminstration of the prescriptions increased the formation of endogenous spleen colony (p0.05) and reduced the frequency of radiation-induced apoptosis (p0.05). No significant difference in effects between irradiated and non-irradiated prescreption on the parameters was found in mice administered with each prescription before exposure to gamma-rays. In non-exposed mice, there were no different findings in the parameters between irradiated and non-irradiated prescription

  18. ANTI-INFLAMATORY ACTIVITY OF SOME INDIAN MEDICINAL PLANTS

    OpenAIRE

    Thenmozhi, V.; Elango, V.; Sadique, J.

    1989-01-01

    The anti-inflamatory activity of some of the medicinal plants were assayed at a dose of 1000 mg/kg b.wt. in male albino rats using Carrageenin induced rat raw edema. Among the fifteen medicinal plants were found to be highly effective which are discussed in this paper.

  19. Anti-inflamatory activity of some Indian medicinal plants.

    Science.gov (United States)

    Thenmozhi, V; Elango, V; Sadique, J

    1989-01-01

    The anti-inflamatory activity of some of the medicinal plants were assayed at a dose of 1000 mg/kg b.wt. in male albino rats using Carrageenin induced rat raw edema. Among the fifteen medicinal plants were found to be highly effective which are discussed in this paper.

  20. Medicinal plants sold at the El Rio Market, Camaguey, Cuba

    NARCIS (Netherlands)

    Godinez-Caraballo, D.; Volpato, G.

    2008-01-01

    Information regarding medicinal plants sold in the El Rio Market, Camaguey, Cuba, revealed 184 species belonging to 69 vascular plant families. The most important family was Fabaceae s.l. with 13 species, followed by Lamiaceae with 12, and Asteraceae with 8. More than 90 general medicinal indication

  1. Traditional medicinal plants in Ben En National Park, Vietnam

    NARCIS (Netherlands)

    Van Sam, Hoang; Baas, P.; Keßler, P.J.A.

    2008-01-01

    This paper surveys the medicinal plants and their traditional use by local people in Ben En National Park, Vietnam. A total of 230 medicinal plant species (belonging to 200 genera and 84 families) is used by local people for treatment of 68 different diseases. These include species that are collecte

  2. Antioxidant activity of some Turkish medicinal plants.

    Science.gov (United States)

    Karadeniz, A; Çinbilgel, I; Gün, S Ş; Çetin, A

    2015-01-01

    DPPH, superoxide and nitric oxide radical scavenging activities and total phenolic content (TPC) of some less known plants, distributed in Burdur-Antalya provinces and consumed both as food and for the medicine, Asplenium ceterach L. (golden herb), Valeriana dioscoridis Sm. (valerian), Doronicum orientale Hoffm. (tiger herb), Cota pestalozzae (Boiss.) Boiss. (camomile), Eremurus spectabilis M. Bieb. (foxtail lily), Asphodeline lutea (L.) Rchb. (asphodel) and Smyrnium connatum Boiss. and Kotschy (hemlock) were investigated. As a result, the highest 2,2-diphenyl-1-picril hydrazyl (DPPH) radical scavenging activity was determined in C. pestalozzae extract (IC50 = 18.66 μg mL(-1)), the highest superoxide and nitric oxide radical scavenging activity was determined in A. ceterach extract (IC50 = 145.17 and 372.03 μg mL(-1)). The highest TPC was determined in A. ceterach extract (59,26 μg mL(-1)) as gallic acid equivalent. Further bioactivity and phytochemistry studies on these plants may enlighten new drug discovery researches. PMID:25649168

  3. Some Plants used in Ayurvedic and Homoeopathic Medicine

    OpenAIRE

    Joshi, R. P.; Veena Joshi

    2013-01-01

    Traditional medicines are used by about 60% of the world’s population. These are used for primary health care, not only in rural areas of developing nations but they are also used in the developed countries where modern medicine are pre dominantly used. In the western world the use of medicinal herbs is continuously growing, approximately 40% of the population is using herbs for medical illness due to increased incidences of adverse effects of allopathic medicine. There are about 45000 plant ...

  4. Regulating Traditional Chinese Medicine Practitioners and Acupuncturists in Ontario, Canada

    Directory of Open Access Journals (Sweden)

    Glen E. Randall

    2015-12-01

    Full Text Available In 2006, the Ontario government passed the Traditional Chinese Medicine Act, which granted Traditional Chinese Medicine practitioners and Acupuncturists (TCM/A practitioners self-regulatory status under the Regulated Health Professions Act, 1991. The goal of the legislation was to create a new regulatory college that would set and enforce high standards of care and safety in order to enhance public protection and access to a range of traditional and alternative therapies. In April 2013, the College of Traditional Chinese Medicine Practitioners and Acupuncturists of Ontario was officially launched. Several factors account for the government’s decision to delegate self-regulatory authority to TCM/A practitioners through the creation of a regulatory college. In particular, the government’s decision seems to have been influenced by lobbying of some practitioners, greater public acceptance of alternative medicines, patient safety concerns related to acupuncture cases in the media, and the precedence of self-regulatory status being granted to these practitioners in other provinces. The degree to which the legislation has achieved its goals is difficult to determine given the short period of time the regulatory college has existed. However, the fact that the college has developed standards of practice to guide TCM/A practitioners and has a process in place to address public complaints is an early indication of movement toward achieving the policy’s goals. Le gouvernement de l'Ontario a fait voter en 2006 la Loi sur les praticiens en médecine traditionnelle chinoise, qui accorde aux praticiens en médecine traditionnelle chinoise et aux acupuncteurs (praticiens en MTC/A le statut de profession autonome dans le cadre la Loi sur les professions de la santé réglementées de 1991. Le but de la Loi était de créer un ordre professionnel capable d'établir et appliquer des normes de qualité et de sécurité des soins, ceci dans le but d

  5. Hypertension knowledge in urban elderly patients: comparison between adherents to traditional Chinese medicine and Western medicine

    Institute of Scientific and Technical Information of China (English)

    Jiangping Lin; Huining Lei; Fang Liu

    2008-01-01

    Objective To compare knowledge about hypertension between elderly Chinese urban patients with preferences for either traditional Chinese medicine (TCM) or Western medicine (WM).Methods Elderly (≥ 65 years old) patients with hypertension who prefer TCM treatment (n=112) or WM (n=126) were questioned about hypertension.Their answers were compared.Results Only 32.6% of participants correctly identified hypertension as a main risk factor of coronary heart disease and stroke,22.3% of patients answered that the main purpose of hypertension control was preventing cardiovascular disease.Other major reasons for these patients to seek medical treatment for their hypertension included:persuasion by physicians or their family members (21.6%),alleviating symptoms such as headache and dizziness (16.8%),lowering blood pressure without knowing specific reason (12.4%).The predictors for poor knowledge of hypertension were similar irrespective of preference for WM or TCM treatment,and included those with lower levels of education and older age.Television and newspaper (46.8%) were the most frequent sources of hypertension information for both groups.Among those who preferred TCM treatment,"TCM has fewer side effects than WM" and "TCM cures disease while WM only alleviates symptoms" were common beliefs held.Conclusion This study shows that knowledge of hypertension is similar among Chinese urban patients with preferences for either WM or TCM treatment and that misunderstandings about hypertension are common among the elderly patients.In order to control hypertension effectively,public health education is necessary.This should target those with a lower level of education and older age.

  6. Multimedia-based Medicinal Plants Sustainability Management System

    OpenAIRE

    Zacchaeus Omogbadegun; Charles Uwadia; Charles Ayo; Victor Mbarika; Nicholas Omoregbe; Efe Otofia; Frank Chieze

    2011-01-01

    Medicinal plants are increasingly recognized worldwide as an alternative source of efficacious and inexpensive medications to synthetic chemo-therapeutic compound. Rapid declining wild stocks of medicinal plants accompanied by adulteration and species substitutions reduce their efficacy, quality and safety. Consequently, the low accessibility to and non-affordability of orthodox medicine costs by rural dwellers to be healthy and economically productive further threaten their life expectancy. ...

  7. An ethnobotanical survey of medicinal plants in Trinidad

    OpenAIRE

    Clement, Y. N.; Baksh-Comeau, Y. S.; Seaforth, C. E.

    2015-01-01

    Background An ethnobotanical survey was conducted on the Caribbean island of Trinidad to identify medicinal plants commonly used in traditional medicine to treat a variety of medical conditions. Methods A pilot survey was conducted to identify the top ten most common ailments where medicinal plants were used. The results of the foregoing study guided a wider national survey conducted between October 2007 and July 2008. A total of 450 households from 50 rural communities were interviewed using...

  8. Progress in Traditional Chinese and Western Medicine Treatments and Nursing Care of Knee Osteoarthritis

    Institute of Scientific and Technical Information of China (English)

    Xiao-Hua Shen; Yi Cui

    2015-01-01

    This paper reviews the causes of knee osteoarthritis, traditional Chinese and Western medicine therapies and nursing research progress and indicates that traditional Chinese and Western medicine have gradually recognized the cause of knee osteoarthritis. Knee osteoarthritis has been treated with various treatments and nursing care planning, and the combination of traditional Chinese and Western medicine has constantly been improved. Nurses should instruct the discharged patient to correctly treat their disease, adopt the health education, and, via the establishment of a healthy lif-estyle, insist on a functional exercise to relieve the pain, delay disease progression, and improve quality of life.

  9. Screening test for anti-Helicobacter pylori activity of traditional Chinese herbal medicines

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    AIM:To evaluate the anti-Helicobacter pylori (H.pylori) activity of 50 traditional Chinese herbal medicines in order to provide the primary evidence for their use in clinical practice.METHODS:A susceptibility test of water extract from 50 selected traditional Chinese herbal medicines for in vitro H.pylori Sydney strain 1 was performed with broth dilution method.Anti-H.pylori activity of the selected Chinese herbal medicines was evaluated according to their minimum inhibitory concentration (MIC).RESULTS:The ...

  10. Speech at the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instruction on Western Medicine Doctors Learning Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhu

    2009-01-01

    @@ Respected leaders, distinguished guests, venerable seniors and comrades, Today, the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instructions on Western Medicine Doctors Learning Traditional Chinese Medicine was inaugurated by the Chinese Association of Integrative Medicine, and it is also an important occasion to review the past and look forward to the future.

  11. 用的理论开发新型中药%DEVELOPMENT OF NEW CHINESE MEDICINE WITH

    Institute of Scientific and Technical Information of China (English)

    吴凤锷; 吴蔚

    2002-01-01

    我们以现代科技理论为出发点,提出了新理论体系,试图使中外学者对中药的认识趋于一致.中药的本质就是"组合".无论是单方或复方都是一个庞大的分子库.具有相同或相似功能的分子组合成一个群体.这些群体表现出特定的药效."组合"有三层意思:生药的组合、活性分子群的组合与特定疗效的组合.分子群是特定药效功能的物质基础.就是从水平上研究中药及其药效的物质基础,阐明中药活性部位的相互作用与药效的相互关系及其作用机制.的三个新概念:中药功效分子族:具有相似药效作用的一类分子的组合,其骨架及功能团相同或相似.单味中药表征性组合分子:单味中药药效的代表性功效分子族,即主要药效分子组合.单味中药非表性组合分子:单味中药表征性分子以外的其它功效分子族,即辅助药效分子的组合.的主要研究范围:中药药效的组合分子学基础(植物化学,天然产物);组合分子的药理学基础(分子生物学,细胞生物学,药理学).本文提出了应用研究新型中药的新方法.%In order to expound "Chinese Medicine" with modern sciences and technology,we have suggested atween the west and east,it is difficult to study "Chinese Medicine" for the scholars in the west.activities. The "combination" means:The group of molecules is substantial base of the special activities.Some concepts have been given definitions. is chiefly concerned with the group of combinatorial molecules and thefunctions for "Chinese medicine", and its title reflects the prime importance of the insights that have come thecombinatorial molecules approach. A few important concepts have been included:molecules possessed same or similar activity.the"function unit"for efficeacy therapy of a sort of Chinese medicine(exp.A drug plant or other materials).Other "function units" except "Symbol combinatorial molecule".The research area of "combinatorial

  12. Prof. CHEN Ke-ji Winning the Prize of "Ren Ji Cup" for International Contribution to Chinese Medicine by WFCMS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ In order to promote the exchange and cooperation of Chinese medicine among the states and regions globally and fasten the step of Chinese medicine to the world, the World Federation of Chinese Medicine Societies (WFCMS) has set up an award for those who have greatly contributed to medical treatment, education, scientific research of Chinese medicine, and the establishment of the statutory registration of Chinese medicine. The First International Contribution to Chinese Medicine Award Ceremony was held on April 10 at the Great Hall of the People in China. Prof. CHEN Ke-ji (China), Lin Tzi Chang (Australia) and David Molony (U.S.A) were awarded "Ren Ji Cup", the Prize for International Contribution to Chinese Medicine.

  13. Gitksan medicinal plants-cultural choice and efficacy

    Directory of Open Access Journals (Sweden)

    Johnson Leslie

    2006-06-01

    Full Text Available Abstract Background The use of plants for healing by any cultural group is integrally related to local concepts of the nature of disease, the nature of plants, and the world view of the culture. The physical and chemical properties of the plants themselves also bear on their selection by people for medicines, as does the array of plants available for people to choose from. I examine use of medicinal plants from a "biobehavioral" perspective to illuminate cultural selection of plants used for medicine by the Gitksan of northwestern British Columbia, Canada. Methods Consultant consensus, "intercultural consensus", independent use of the same plants by other cultural groups, and phytochemistry and bioassay results from the literature, were employed in analysis of probable empirical efficacy of plant uses. Results 70% of 37 Gitksan medicinal plants were used similarly by other cultures where direct diffusion is not known to have occurred; eleven plants, including the eight most frequently mentioned medicinal plants, also show active phytochemicals or bioassays indicating probable physiologically based therapeutic effects. Conclusion Analysis of intercultural consensus revealed that the majority of cultures in the British Columbia region within the plant ranges use the same plants, or closely related species, in similar ways. The rigor of this analysis is effected by the lack of consistent data on all taxa of interest for all cultures within the region.

  14. Prospects and Challenges of Medicinal Plants Conservation and Traditional Medicine in Tanzania

    OpenAIRE

    Kayombo, Edmund J; Mahunnah, Rogasian L A; Uiso, Febronia C

    2013-01-01

    A qualitative study was carried to assess prospects and challenges of medicinal plants conservation and traditional medicine in Tanzania. The study shows that TRM and medicinal have great prospects in healthcare delivery worldwide. These prospects have more impact in developing countries where 70%-80% of population used TRM for Primary Healthcare (PHC). It is reported that 25% of prescribed drugs in conventional healthcare were derived from their ethnomedicinal use in TRM. Medicin...

  15. Establishing Chinese medicine characteristic tumor response evaluation system is the key to promote internationalization of Chinese medicine oncology.

    Science.gov (United States)

    Li, Jie; Li, Lei; Liu, Rui; Lin, Hong-sheng

    2012-10-01

    The features and advantages of Chinese medicine (CM) in cancer comprehensive treatment have been in the spotlight of experts both at home and abroad. However, how to evaluate the effect of CM more objectively, scientifically and systematically is still the key problem of clinical trial, and also a limitation to the development and internationalization of CM oncology. The change of tumor response evaluation system in conventional medicine is gradually consistent with the features of CM clinical effect, such as they both focus on a combination of soft endpoints (i.e. quality of life, clinical benefit, etc.) and hard endpoints (i.e. tumor remission rate, time to progress, etc.). Although experts have proposed protocols of CM tumor response evaluation criteria and come to an agreement in general, divergences still exist in the importance, quantification and CM feature of the potential endpoints. Thus, establishing a CM characteristic and wildly accepted tumor response evaluation system is the key to promote internationalization of CM oncology, and also provides a more convenient and scientific platform for CM international cooperation and communication.

  16. Commercially Important Medicinal Plants of South Africa: A Review

    Directory of Open Access Journals (Sweden)

    R. A. Street

    2013-01-01

    Full Text Available There is a growing interest in natural plant-based remedies as a source for commercial products. Around 80% of the South African population use traditional medicines to meet their primary health care needs; however, only a few South African medicinal plants have been exploited to their full potential in terms of commercialization. The opportunity for bioprospecting of plant compounds for novel pharmaceuticals remains largely untapped. Certain renowned medicinal plants of international acclaim including buchu and rooibos are currently contributing to local enterprise; however, other exciting opportunities exist for commonly used plants which have not yet reached the international arena. This paper focuses on the key research and development contributions of 10 commercially important medicinal plants of South Africa. Traditional uses, scientific validation, commercialisation developments, as well as both potential opportunities and setbacks are discussed.

  17. [A new strategy for Chinese medicine processing technologies: coupled with individuation processed and cybernetics].

    Science.gov (United States)

    Zhang, Ding-kun; Yang, Ming; Han, Xue; Lin, Jun-zhi; Wang, Jia-bo; Xiao, Xiao-he

    2015-08-01

    The stable and controllable quality of decoction pieces is an important factor to ensure the efficacy of clinical medicine. Considering the dilemma that the existing standardization of processing mode cannot effectively eliminate the variability of quality raw ingredients, and ensure the stability between different batches, we first propose a new strategy for Chinese medicine processing technologies that coupled with individuation processed and cybernetics. In order to explain this thinking, an individual study case about different grades aconite is provided. We hope this strategy could better serve for clinical medicine, and promote the inheritance and innovation of Chinese medicine processing skills and theories. PMID:26790315

  18. Systematic organization of medicinal plant information: a monograph template proposal

    Directory of Open Access Journals (Sweden)

    Ana C.B. Carvalho

    2014-01-01

    Full Text Available The use of medicinal plants in Brazil is widespread and is supported by public policies; it has the objective of providing the population with safe and effective herbal medicines of adequate quality. An action in these policies is to develop medicinal plant monographs to gather published information and decide which medicinal plants should be financed by the Brazilian government and distributed by the public health system. Currently, the monographs published worldwide do not present unified information regarding medicinal plants, and generally, they do not cover enough requirements for herbal medicine registration. The aim of this study is to develop a monograph model with standardized information not only about botany, agronomy, quality control, safety, and efficacy but also about relating regulatory aspects that support herbal medicine regulation. The development of standardized monographs favors the fast authorization and distribution of herbal medicines in the public system. The model also points out the lacking studies that should be carried out to supplement the necessary regulatory information of medicinal plants.

  19. The microbiome of medicinal plants: diversity and importance for plant growth, quality and health.

    Science.gov (United States)

    Köberl, Martina; Schmidt, Ruth; Ramadan, Elshahat M; Bauer, Rudolf; Berg, Gabriele

    2013-01-01

    Past medicinal plant research primarily focused on bioactive phytochemicals, however, the focus is currently shifting due to the recognition that a significant number of phytotherapeutic compounds are actually produced by associated microbes or through interaction with their host. Medicinal plants provide an enormous bioresource of potential use in modern medicine and agriculture, yet their microbiome is largely unknown. The objective of this review is (i) to introduce novel insights into the plant microbiome with a focus on medicinal plants, (ii) to provide details about plant- and microbe-derived ingredients of medicinal plants, and (iii) to discuss possibilities for plant growth promotion and plant protection for commercial cultivation of medicinal plants. In addition, we also present a case study performed both to analyse the microbiome of three medicinal plants (Matricaria chamomilla L., Calendula officinalis L., and Solanum distichum Schumach. and Thonn.) cultivated on organically managed Egyptian desert farm and to develop biological control strategies. The soil microbiome of the desert ecosystem was comprised of a high abundance of Gram-positive bacteria of prime importance for pathogen suppression under arid soil conditions. For all three plants, we observed a clearly plant-specific selection of the microbes as well as highly specific diazotrophic communities that overall identify plant species as important drivers in structural and functional diversity. Lastly, native Bacillus spec. div. strains were able to promote plant growth and elevate the plants' flavonoid production. These results underline the numerous links between the plant-associated microbiome and the plant metabolome. PMID:24391634

  20. Effects of gamma irradiation on antioxidants of medicinal plants

    International Nuclear Information System (INIS)

    The antioxidant effect of water extracts from irradiated medicinal plants on inhibition of lipid peroxidation in human plasma was examined. The results presented herein indicate that crude extracts from 29 kinds, 31 extracts, of medicinal plants, irradiated at 10 and 25 kilo gray. showed no significant change in inhibition of lipid peroxidation in plasma induced by gamma irradiation (p<0.05). It also found that extraction yields in some irradiated plants were increased

  1. Application of Bioinformatics and Systems Biology in Medicinal Plant Studies

    Institute of Scientific and Technical Information of China (English)

    DENG You-ping; AI Jun-mei; XIAO Pei-gen

    2010-01-01

    One important purpose to investigate medicinal plants is to understand genes and enzymes that govern the biological metabolic process to produce bioactive compounds.Genome wide high throughput technologies such as genomics,transcriptomics,proteomics and metabolomics can help reach that goal.Such technologies can produce a vast amount of data which desperately need bioinformatics and systems biology to process,manage,distribute and understand these data.By dealing with the"omics"data,bioinformatics and systems biology can also help improve the quality of traditional medicinal materials,develop new approaches for the classification and authentication of medicinal plants,identify new active compounds,and cultivate medicinal plant species that tolerate harsh environmental conditions.In this review,the application of bioinformatics and systems biology in medicinal plants is briefly introduced.

  2. Principle, traits and functions of electrochemical fingerprint of Chinese traditional medicine

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    In regard to such challenging analysis problems as scientific identification and quality evaluation of Chinese traditional medicine, the electrochemical fingerprint technique of Chinese traditional medicine has been researched. The principle, traits, functions, etc., of the electrochemical fingerprint have detailedly been analyzed and discussed by the B-Z oscillatory system using malonic acid as main dissipation substance, characterized by the fact that different influences of different Chinese traditional medicines on the mechanism of the oscillatory reaction cause different changes of the shape of the potential-time curve of the oscillatory system under the conditions of constant temperature and pressure. An economical, simple and convenient, easy pushing and effective scientific method for distinguishing and evaluating multifarious Chinese traditional medicines has successfully been put forward.

  3. Effects and Mechanisms of Chinese Herbal Medicine in Ameliorating Myocardial Ischemia-Reperfusion Injury

    Directory of Open Access Journals (Sweden)

    Qing Liu

    2013-01-01

    Full Text Available Myocardial ischemia-reperfusion (MIR injury is a major contributor to the morbidity and mortality associated with coronary artery disease, which accounts for approximately 450,000 deaths a year in the United States alone. Chinese herbal medicine, especially combined herbal formulations, has been widely used in traditional Chinese medicine for the treatment of myocardial infarction for hundreds of years. While the efficacy of Chinese herbal medicine is well documented, the underlying molecular mechanisms remain elusive. In this review, we highlight recent studies which are focused on elucidating the cellular and molecular mechanisms using extracted compounds, single herbs, or herbal formulations in experimental settings. These studies represent recent efforts to bridge the gap between the enigma of ancient Chinese herbal medicine and the concepts of modern cell and molecular biology in the treatment of myocardial infarction.

  4. Thirty-five Infantile Purpura Nephritis Patients Treated with Integrated Traditional Chinese and Western Medicine

    Institute of Scientific and Technical Information of China (English)

    ZHENG; Tian-wen

    2001-01-01

    Thirty-five patients of infantile purpura nephritis (IPN) were treated with integrated traditional Chinese and western medicine (TCM-WM) from January 1994 to December 1998, with good efficacy obtained, and following is the report.

  5. Screening for hemostatic activities of popular Chinese medicinal herbs in vitro

    Directory of Open Access Journals (Sweden)

    Naoki Ohkura

    2015-03-01

    Conclusion Some popular Chinese medicinal herbs have potential as hemostatic agents and could thus be developed as new strategies for the treatment and prevention of bleeding. [J Intercult Ethnopharmacol 2015; 4(1.000: 19-23

  6. [Opportunity and challenge of post-marketing evaluation of traditional Chinese medicine].

    Science.gov (United States)

    Du, Xiao-Xi; Song, Hai-Bo; Ren, Jing-Tian; Yang, Le; Guo, Xiao-Xin; Pang, Yu

    2014-09-01

    Post-marketing evaluation is a process which evaluate the risks and benefits of drug clinical application comprehensively and systematically, scientific and systematic results of post-marketing evaluation not only can provide data support for clinical application of traditional Chinese medicine, but also can be a reliable basis for the supervision department to develop risk control measures. With the increasing demands for treatment and prevention of disease, traditional Chinese medicine has been widely used, and security issues are also exposed. How to find risk signal of traditional Chinese medicine in the early stages, carry out targeted evaluation work and control risk timely have become challenges in the development of traditional Chinese medicine industry. PMID:25532372

  7. Effects of Traditional Chinese Patent Medicine on Essential Hypertension

    Science.gov (United States)

    Xiong, Xingjiang; Wang, Pengqian; Zhang, Yuqing; Li, Xiaoke

    2015-01-01

    Abstract Traditional Chinese patent medicine (TCPM) is widely used for essential hypertension (EH) in China. However, there is no critically appraised evidence, such as systematic reviews or meta-analyses, regarding the potential benefits and disadvantages of TCPM to justify their clinical use and recommendation. The aim of this review was to systematically evaluate and meta-analyze the effects of TCPM for EH. Seven databases, the Cochrane Library, PubMed, EMBASE, the China National Knowledge Infrastructure, the Chinese Scientific Journal Database, the Chinese Biomedical Literature Database, and the Wanfang Database, were searched from their inception to August 2014 for relevant studies that compared one TCPM plus antihypertensive drugs versus antihypertensive drugs alone. The methodological quality of the included trials was assessed using the Cochrane risk-of-bias tool. The primary outcome measures were mortality or progression to severe complications and adverse events. The secondary outcome measures were blood pressure (BP) and quality of life (QOL). Seventy-three trials, which included 8138 patients, on 17 TCPMs were included. In general, the methodological quality was low. Two trials evaluated the effects of TCPMs on mortality and the progression to severe complications after treatment, and no significant difference was identified compared with antihypertensive drugs alone. No severe adverse events were reported. Thirteen TCPMs used in complementary therapy significantly decreased systolic BP by 3.94 to 13.50 mmHg and diastolic BP by 2.28 to 11.25 mmHg. QOL was significantly improved by TCPM plus antihypertensive drugs compared with antihypertensive drugs alone. This systematic review provided the first classification of clinical evidence for the effectiveness of TCPM for EH. The usage of TCPMs for EH was supported by evidence of class level III. As a result of the methodological drawbacks of the included studies, more rigorously designed randomized

  8. Are medicinal plants polluted with phthalates?

    Science.gov (United States)

    Saeidnia, Soodabeh; Abdollahi, Mohammad

    2013-05-29

    Phthalic acid esters (PAEs) have been employed in polymer materials as a plasticizer to form them more flexible, adhesive, and soluble. These compounds are mainly used in paints, varnishes, personal cares, cosmetics, paper coatings, and adhesives even in bottled waters, shampoo, body deodorant, hairspray, and gels. Phthalates are able to possess remarkable toxic variations depending on their structures. So far, Di-(2-EthylHexyl) Phthalate DEHP and Di-n- Butyl Phthalate DBP have been found to cause reproductive and developmental toxicities. The U.S. Environmental Protection Agency (EPA) classified DEHP as probable human carcinogen. To the best of our knowledge, phthalates showed diverse toxicity profiles according to their structures in the liver, kidneys, thyroid, and testes, which are involved in general toxicity. Furthermore, they are introduced as hormonally-active agents, because they can interfere with the endocrine system in human. Incidence of developmental abnormalities (like skeletal malformations and cleft palate, and undescended testes, lowering testes weight and anogenital distance) seems increasing via high exposure to phthalate metabolites. Although, increasing the capacity for phthalate free plasticizer productions is the first step to restrict the distribution of these toxic manmade compounds, finding the new ways for phthalate absorption from the soil in agricultural fields may have benefits. Also, evaluation and examination of diverse sources of medicinal and food plants to determine the level of phthalate accumulation in their organs are extremely recommended to avoid creating toxicity particularly in reproductive systems.

  9. Are Medicinal Plants Polluted with Phthalates?

    Directory of Open Access Journals (Sweden)

    Soodabeh Saeidnia

    2013-05-01

    Full Text Available Phthalic acid esters (PAEs have been employed in polymer materials as a plasticizer to form them more flexible, adhesive, and soluble. These compounds are mainly used in paints, varnishes, personal cares, cosmetics, paper coatings, and adhesives even in bottled waters, shampoo, body deodorant, hairspray, and gels. Phthalates are able to possess remarkable toxic variations depending on their structures. So far, Di-(2-EthylHexyl Phthalate DEHP and Di-n- Butyl Phthalate DBP have been found to cause reproductive and developmental toxicities. The U.S. Environmental Protection Agency (EPA classified DEHP as probable human carcinogen. To the best of our knowledge, phthalates showed diverse toxicity profiles according to their structures in the liver, kidneys, thyroid, and testes, which are involved in general toxicity. Furthermore, they are introduced as hormonally-active agents, because they can interfere with the endocrine system in human. Incidence of developmental abnormalities (like skeletal malformations and cleft palate, and undescended testes, lowering testes weight and anogenital distance seems increasing via high exposure to phthalate metabolites. Although, increasing the capacity for phthalate free plasticizer productions is the first step to restrict the distribution of these toxic manmade compounds, finding the new ways for phthalate absorption from the soil in agricultural fields may have benefits. Also, evaluation and examination of diverse sources of medicinal and food plants to determine the level of phthalate accumulation in their organs are extremely recommended to avoid creating toxicity particularly in reproductive systems.

  10. The microbiome of medicinal plants: diversity and importance for plant growth, quality and health

    Science.gov (United States)

    Köberl, Martina; Schmidt, Ruth; Ramadan, Elshahat M.; Bauer, Rudolf; Berg, Gabriele

    2013-01-01

    Past medicinal plant research primarily focused on bioactive phytochemicals, however, the focus is currently shifting due to the recognition that a significant number of phytotherapeutic compounds are actually produced by associated microbes or through interaction with their host. Medicinal plants provide an enormous bioresource of potential use in modern medicine and agriculture, yet their microbiome is largely unknown. The objective of this review is (i) to introduce novel insights into the plant microbiome with a focus on medicinal plants, (ii) to provide details about plant- and microbe-derived ingredients of medicinal plants, and (iii) to discuss possibilities for plant growth promotion and plant protection for commercial cultivation of medicinal plants. In addition, we also present a case study performed both to analyse the microbiome of three medicinal plants (Matricaria chamomilla L., Calendula officinalis L., and Solanum distichum Schumach. and Thonn.) cultivated on organically managed Egyptian desert farm and to develop biological control strategies. The soil microbiome of the desert ecosystem was comprised of a high abundance of Gram-positive bacteria of prime importance for pathogen suppression under arid soil conditions. For all three plants, we observed a clearly plant-specific selection of the microbes as well as highly specific diazotrophic communities that overall identify plant species as important drivers in structural and functional diversity. Lastly, native Bacillus spec. div. strains were able to promote plant growth and elevate the plants’ flavonoid production. These results underline the numerous links between the plant-associated microbiome and the plant metabolome. PMID:24391634

  11. Phylogenetic exploration of commonly used medicinal plants in South Africa.

    Science.gov (United States)

    Yessoufou, Kowiyou; Daru, Barnabas H; Muasya, Abraham Muthama

    2015-03-01

    The rapid growth rate of human population, along with the public health crisis encountered in many regions, particularly in developing world, creates an urgent need for the discovery of alternative drugs. Because medicinal plants are not distributed randomly across lineages, it has been suggested that phylogeny along with traditional knowledge of plant uses can guide the identification of new medicinally useful plants. In this study, we combined different statistical approaches to test for phylogenetic signal in 33 categories of plant uses in South Africa. Depending on the null models considered, we found evidence for signal in up to 45% of plant use categories, indicating the need for multiple tests combination to maximize the chance of discovering new medicinal plants when applying a phylogenetic comparative approach. Furthermore, although there was no signal in the diversity of medicinal uses-that is, total number of medicinal uses recorded for each plant-our results indicate that taxa that are evolutionarily closely related have significantly more uses than those that are evolutionarily isolated. Our study therefore provides additional support to the body of the literature that advocates for the inclusion of phylogeny in bioscreening medicinal flora for the discovery of alternative medicines.

  12. Prescriptions of Chinese Herbal Medicines for Insomnia in Taiwan during 2002

    OpenAIRE

    Fang-Pey Chen; Maw-Shiou Jong; Yu-Chun Chen; Yen-Ying Kung; Tzeng-Ji Chen; Fun-Jou Chen; Shinn-Jang Hwang

    2011-01-01

    Chinese herbal medicine (CHM) has been commonly used for treating insomnia in Asian countries for centuries. The aim of this study was to conduct a large-scale pharmaco-epidemiologic study and evaluate the frequency and patterns of CHM use in treating insomnia. We obtained the traditional Chinese medicine (TCM) outpatient claims from the National Health Insurance in Taiwan for the year 2002. Patients with insomnia were identified from the diagnostic code of International Classification of Dis...

  13. Evaluation of Antioxidant and Antimicrobial Activities from 28 Chinese Herbal Medicines

    OpenAIRE

    Ho-Yang Lin; Li-Yeh Chuang; Hsueh-Wei Chang; Cheng-Hong Yang

    2013-01-01

    Background: Many Chinese medicines have been reported to exhibit high antimicrobial and antioxidantactivities. In this study, 28 traditional Chinese herbal medicines were tested for their antioxidant and antibacterial activities.Materials and Methods: Total flavonoid content of the ethanol extracts were determined by a colorimetric method. Total phenol content was estimated as gallic acid equivalents. The antioxidant activities of the extracts were evaluated by various antioxidant assays, inc...

  14. [Research on our hospital inventory management status quo of traditional Chinese medicine drugs and treatment method].

    Science.gov (United States)

    Zhang, Ying-Nan; Xu, Wen

    2014-03-01

    Under the background of the new medical reform, a large variety of traditional Chinese medicine from complicated sources, Chinese traditional medicine of actor of true and false of the quality directly affect the drug safety and clinical efficacy, but also relate to the social and economic benefits of hospital. Along with the development of the modern management of medical institutions and drug circulation circulation system reform in our country, the hospital drug inventory, supply and management work is an important topic for the pharmaceutical trading. However, there is always contradiction, dispensary need to supple pharmacy, in order to satisfy the demands of hospital patients with normal diagnosis and treatment work. However, if the drug inventory is too much, not only increases the drug monitoring problem, at the same time, but also causes storage costs rise. Therefore, completing scientific and reasonable storage and management becomes urgent problems at present. Wherefore, our country administration of traditional Chinese medicine in 2007 promulgated the "Chinese traditional medicine yinpian management norms in hospital", aims to standardize management of Chinese traditional medicine quality and improve the safety of drugs. The author through looking up information and visiting survey, to understand the currently existing problems, and summarizes the literature inland and abroad in recent years Chinese medicine drug inventory management work experience, in view of status quo of Chinese medicine inventory management in China, put forward the solution. To guarantee TCM pharmacy management more standardized, more standard, to adapt to the new reform of Chinese traditional medicine industry, improve the management level of hospital, defend the hospital's reputation and the patient's interests.

  15. CLINICAL OBSERVATION ON TREATMENT OF CHRONIC PHARYNGITIS WITH ACUPUNCTURE PLUS CHINESE HERBAL MEDICINES

    Institute of Scientific and Technical Information of China (English)

    聂荣华

    2003-01-01

    @@ Chronic pharyngitis is the diffuse inflammation of the pharyngeal mucus, submucosal and lymph tissues. Traditional Chinese medicine (TCM) considers it to be the category of "Meiheqi" (梅核气,globus hystericus), "Shiyin" (失音,aphonia) and "Houbi" (喉痹,inflammation of the throat). According to the theory of TCM, the author of the present paper adopted acupuncture plus Chinese herbal medicines to treat it from 1990 to 2002, and achieved a satisfactory result. It is reported as follows.

  16. Antiviral Activities of Several Oral Traditional Chinese Medicines against Influenza Viruses

    OpenAIRE

    Lin-Lin Ma; Miao Ge; Hui-Qiang Wang; Jin-Qiu Yin; Jian-Dong Jiang; Yu-Huan Li

    2015-01-01

    Influenza is still a serious threat to human health with significant morbidity and mortality. The emergence of drug-resistant influenza viruses poses a great challenge to existing antiviral drugs. Traditional Chinese medicines (TCMs) may be an alternative to overcome the challenge. Here, 10 oral proprietary Chinese medicines were selected to evaluate their anti-influenza activities. These drugs exhibit potent inhibitory effects against influenza A H1N1, influenza A H3N2, and influenza B virus...

  17. [Analyses on positive influence of harmonous development of traditional Chinese medicine compounds' researchs and patent protection].

    Science.gov (United States)

    Yang, Xujie; Xiao, Shiying; Guo, Zan; Wang, Zhimin; You, Yun

    2012-01-01

    Current patent protection of traditional Chinese medicine (TCM) compounds is far from being satisfactory with increasing research and development achievements. As patent protection of traditional Chinese medicine compounds is closely related with many fields such as research and development of new TCM drugs, industrial development and TCM internationalization, the development of research and harmonious development of TCM compounds and their patent protection is bound to have a far-reaching influence on domestic and even international societies. PMID:22741453

  18. Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan.

    Science.gov (United States)

    Al-Qura'n, S

    2009-05-01

    Two main research questions are framing this investigation: (1) the main taxa of the medicinal importance value altered the Showbak forest stand and species composition? (2) The most safe species and what are the toxic ones (unsafe). These two research questions are the vital ones to draw a clear image about the wild medicinal plants of this investigated area of Showbak region in Jordan. 79 wild medicinal plant species were investigated in this study which are used in traditional medication for the treatment of various diseases. Most of the locals interviewed dealt with well-known safe medicinal plants such as Aaronsohnia factorovskyi Warb. et Eig., Achillea santolina L., Adiantum capillus-veneris L., Artemisia herba-alba L., Ceratonia siliqua L., Clematis recta L., Herniaria hirsuta L., Malva neglecta Wallr., Rosmarinus officinalis L., Ruta chalepensis L., Salvia triloba L., Sarcopoterium spinosa (L.) Spach., Thymbra capitata (L.) Hof, and Urginea maritima Barker. Many of the wild medicinal plants investigated were toxic and needed to be practiced by practitioners and herbalists rather than the local healers. These plants include Calotropis procera Willd R.Br., Citrullus colocynthis (L.) Sch., Datura stramonium L., Digitalis purpurea L., Ecballium elaterium (L.) A.Rich., Euphorbia helioscopia L., Euphorbia tinctoria Boiss., Glaucium corniculatum (L.) Curt., Hyoscyamus aureus L., Mandragora officinarum L., Nerium oleander L., Ricinus communis L., Solanum nigrum L., Withania somnifera (L.) Dunel. The conservation of medicinal plants and natural resources is becoming increasingly important, so this research is trying to collect information from local population concerning the use of medicinal plants in Showbak; identify the most important specie; determine the relative importance value of the species and calculate the informant consensus factor (ICF) for the medicinal plants. Obtaining results is relied on the interviewee's personal information and the medicinal use

  19. Ethnopharmacological survey of wild medicinal plants in Showbak, Jordan.

    Science.gov (United States)

    Al-Qura'n, S

    2009-05-01

    Two main research questions are framing this investigation: (1) the main taxa of the medicinal importance value altered the Showbak forest stand and species composition? (2) The most safe species and what are the toxic ones (unsafe). These two research questions are the vital ones to draw a clear image about the wild medicinal plants of this investigated area of Showbak region in Jordan. 79 wild medicinal plant species were investigated in this study which are used in traditional medication for the treatment of various diseases. Most of the locals interviewed dealt with well-known safe medicinal plants such as Aaronsohnia factorovskyi Warb. et Eig., Achillea santolina L., Adiantum capillus-veneris L., Artemisia herba-alba L., Ceratonia siliqua L., Clematis recta L., Herniaria hirsuta L., Malva neglecta Wallr., Rosmarinus officinalis L., Ruta chalepensis L., Salvia triloba L., Sarcopoterium spinosa (L.) Spach., Thymbra capitata (L.) Hof, and Urginea maritima Barker. Many of the wild medicinal plants investigated were toxic and needed to be practiced by practitioners and herbalists rather than the local healers. These plants include Calotropis procera Willd R.Br., Citrullus colocynthis (L.) Sch., Datura stramonium L., Digitalis purpurea L., Ecballium elaterium (L.) A.Rich., Euphorbia helioscopia L., Euphorbia tinctoria Boiss., Glaucium corniculatum (L.) Curt., Hyoscyamus aureus L., Mandragora officinarum L., Nerium oleander L., Ricinus communis L., Solanum nigrum L., Withania somnifera (L.) Dunel. The conservation of medicinal plants and natural resources is becoming increasingly important, so this research is trying to collect information from local population concerning the use of medicinal plants in Showbak; identify the most important specie; determine the relative importance value of the species and calculate the informant consensus factor (ICF) for the medicinal plants. Obtaining results is relied on the interviewee's personal information and the medicinal use

  20. Historical versus contemporary medicinal plant uses in Ghana

    DEFF Research Database (Denmark)

    Soelberg, Jens; Asase, A; Akwetey, G;

    2015-01-01

    ETHNOPHARMACOLOGICAL RELEVANCE: Three extraordinary, historical documents stemming from observations made in 1697, 1803 and 1817 quote medicinal plant uses among the Fante, Ga and Ashanti people of present-day Ghana, and can be linked to original botanical specimens in European herbaria....... This provides a unique opportunity to gain insight to the historical materia medica of Ghana and compare this to contemporary medicinal plant uses. By critical literary and taxonomic review, the present study (re-)establishes the earliest known history of many important Ghanaian medicinal plants, and assesses...... the scale of change and loss of medicinal plant knowledge in Ghana over time. The study provides the foundation to reconstruct lost or discontinued Ghanaian plant uses in local or ethnopharmacological contexts. MATERIALS AND METHODS: Historical botanical specimens were located in the herbaria of University...

  1. A meta-analysis of Chinese herbal medicines for vascular dementia

    Institute of Scientific and Technical Information of China (English)

    Xiude Qin; Yu Liu; Yanqing Wu; Shuo Wang; Dandan Wang; Jinqiang Zhu; Qiaofeng Ye; Wei Mou; Liyuan Kang

    2013-01-01

    OBJECTIVE: To investigate the efficacy and safety of Chinese herbal medicines in the treatment of patients with vascular dementia.DATA RETRIEVAL: We retrieved publications from Cochrane Library (2004 to July 2011), PubMed (1966 to July 2011), the Chinese Science and Technique Journals Database (1977 to July 2011), the China National Knowledge Infrastructure (1979 to July 2011), Google Scholar (July 2011), and the Chinese Biomedical Database (1977 to July 2011) using the key words "Chinese medicine OR Chinese herbal medicine" and "vascular dementia OR mild cognition impair OR multi-infarct dementia OR small-vessel dementia OR strategic infarct dementia OR hypoperfusion dementia OR hemorrhagic dementia OR hereditary vascular dementia".MAIN OUTCOME MEASURES: Effective rate, Mini-Mental State Examination scores, Hasegawa Dementia Scale scores, and incidence of adverse reactions.CONCLUSION: Chinese herbal medicine appears to be safer and more effective than control measures in the treatment of vascular dementia. However, the included trials were generally low in quality. More well-designed, high-quality trials are needed to provide better evidence for the assessment of the efficacy and safety of Chinese medicines for vascular dementia.

  2. Medicinal plants used as excipients in the history in Ghanaian herbal medicine

    DEFF Research Database (Denmark)

    Freiesleben, Sara Holm; Soelberg, Jens; Jäger, Anna

    2015-01-01

    Ethnopharmacological relevance The present study was carried out to investigate the traditional use, pharmacology and active compounds of four plants commonly used as excipients in herbal medicine in Ghana. Materials and methods A comprehensive literature search was conducted to gain knowledge...... as excipients could rely on their taste properties. Conclusion The present study suggests that there may be more than one simple explanation for the use of these four plants as excipients. Plausible explanations have been proven to be: (1) a way to increase the effect of the medicine, (2) a way to make...... the medicine more palatable or (3) a way to preserve the activity of the medicinal preparation over time....

  3. Traditional Chinese medicine in diagnosis and treatment of fibromyalgia syndrome.

    Science.gov (United States)

    Aliyev, R; Vieth, T; Geiger, G

    2010-11-01

    Fibromyalgia Syndrome (FS) is known for the difficulties arising from classification. The accompanying pain in skeletal muscles, myofascial peri-articular structures and a number of polymorphic symptoms cannot be separated into complexes of symptoms. The application of principles of Traditional Chinese Medicine (TCM) helps in analyzing the symptoms of FS to detect a leading syndrome and thereby establish an individual therapy. Medical histories and objective examinations of 25 patients with FS and 22 patients with vertebrogenic pain syndromes were analyzed according to TCM. A questionnaire was used to determine the leading constitutional type according to the 5-elements-theory. Analyses of the results showed that 83% of patients with FS were of constitutional type of the element earth. The following syndromes were found to be important in FS: 1) liver-Qi-stagnation, 2) Yin and blood deficiency of the liver, 3) Yang-weakness of the spleen and kidney, 4) Yin-weakness of the kidney. Applying TCM for FS allows for separating a group of symptoms and thus individual therapy. The determination of the constitutional type according to the 5-elements-theory may be used for a better understanding of the disharmony pattern.

  4. The Progress of Metabolomics Study in Traditional Chinese Medicine Research.

    Science.gov (United States)

    Wang, Pengcheng; Wang, Qiuhong; Yang, Bingyou; Zhao, Shan; Kuang, Haixue

    2015-01-01

    Traditional Chinese medicine (TCM) has played important roles in health protection and disease treatment for thousands of years in China and has gained the gradual acceptance of the international community. However, many intricate issues, which cannot be explained by traditional methods, still remain, thus, new ideas and technologies are needed. As an emerging system biology technology, the holistic view adopted by metabolomics is similar to that of TCM, which allows us to investigate TCM with complicated conditions and multiple factors in depth. In this paper, we tried to give a timely and comprehensive update about the methodology progression of metabolomics, as well as its applications, in different fields of TCM studies including quality control, processing, safety and efficacy evaluation. The herbs investigated by metabolomics were selected for detailed examination, including Anemarrhena asphodeloides Bunge, Atractylodes macrocephala Kidd, Pinellia ternate, etc.; furthermore, some valuable results have been obtained and summarized. In conclusion, although the study of metabolomics is at the early phase and requires further scrutiny and validation, it still provides bright prospects to dissect the synergistic action of multiple components from TCM. Overall, with the further development of analytical techniques, especially multi-analysis techniques, we expect that metabolomics will greatly promote TCM research and the establishment of international standards, which is beneficial to TCM modernization. PMID:26477800

  5. Treatment of Acute Lymphoblastic Leukemia from Traditional Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Ya-Li Hsiao

    2014-01-01

    Full Text Available Acute lymphoblastic leukemia (ALL is a cancer that immature white blood cells continuously overproduce in the bone marrow. These cells crowd out normal cells in the bone marrow bringing damage and death. Methotrexate (MTX is a drug used in the treatment of various cancer and autoimmune diseases. In particular, for the treatment of childhood acute lymphoblastic leukemia, it had significant effect. MTX competitively inhibits dihydrofolate reductase (DHFR, an enzyme that participates in the tetrahydrofolate synthesis so as to inhibit purine synthesis. In addition, its downstream metabolite methotrexate polyglutamates (MTX-PGs inhibit the thymidylate synthase (TS. Therefore, MTX can inhibit the synthesis of DNA. However, MTX has cytotoxicity and neurotoxin may cause multiple organ injury and is potentially lethal. Thus, the lower toxicity drugs are necessary to be developed. Recently, diseases treatments with Traditional Chinese Medicine (TCM as complements are getting more and more attention. In this study, we attempted to discover the compounds with drug-like potential for ALL treatment from the components in TCM. We applied virtual screen and QSAR models based on structure-based and ligand-based studies to identify the potential TCM component compounds. Our results show that the TCM compounds adenosine triphosphate, manninotriose, raffinose, and stachyose could have potential to improve the side effects of MTX for ALL treatment.

  6. New Effective Treatment of Liver Fibrosis by Chinese Herbal Medicine

    Institute of Scientific and Technical Information of China (English)

    张国梁

    2002-01-01

    @@ Liver fibrosis is an abnormal proliferation pathologic process of intrahepatic fibrous connective tissue that occurs after liver cells have been necrotized and stimulated by inflammatory factors. It is called fibrosis when the pathological change is mild, and liver cirrhosis when the change becomes so severe as to reconstruct the liver lobuli to form pseudolobuli and nodule(1). Liver fibrosis is an important pathological characteristic of chronic hepatopathy and the chief intermediate link to further develop of liver cirrhosis. No ideal remedy for treatment of chronic hepatitic cirrhosis has been found so far. Although some drugs, such as colchicine and penicillamine, had been reported to have the effect of fibrosis inhibition, their clinical application is still limited for the rather severe toxic-side effects. Certain progress have been made from the clinical and experimental studies on anti-fibrosis treatment by traditional Chinese medicine (TCM) carried out widely in China in recent ten years. And here is a general review of the drugs used.

  7. Insomnia in Chinese Medicine: The Heart of the Matter.

    Science.gov (United States)

    O'Brien, Kylie; Weber, Daniel

    2016-09-01

    Chronic insomnia affects a significant proportion of the general population worldwide, and is associated with several serious medical conditions. From the Western scientific literature, hyper-arousal (on the cognitive-emotional, behavioral, autonomic, or central nervous system level) is a final common pathway involved in its pathogenesis. However, from a Chinese medicine (CM) perspective, it is the Heart, capitalized to denote the functional system as described in CM theory, that is the key organ involved in insomnia due to its role as the "seat of consciousness." This article explores how insomnia is understood from the CM perspective, in particular the role of the Heart, and some of the neurophysiological evidence that supports these ancient theoretical understandings. The potential role of the vagus nerve and its relationship with the (biomedical) heart and CM Heart is also examined. Finally, some of the evidence in association with mechanisms of action of acupuncture in insomnia, in particular its impact on cardiovascular variables associated with insomnia, is presented, along with findings of systematic reviews. PMID:27526331

  8. The remote supervisory and controlling experiment system of traditional Chinese medicine production based on Fieldbus

    Science.gov (United States)

    Zhan, Jinliang; Lu, Pei

    2006-11-01

    Since the quality of traditional Chinese medicine products are affected by raw material, machining and many other factors, it is difficult for traditional Chinese medicine production process especially the extracting process to ensure the steady and homogeneous quality. At the same time, there exist some quality control blind spots due to lacking on-line quality detection means. But if infrared spectrum analysis technology was used in traditional Chinese medicine production process on the basis of off-line analysis to real-time detect the quality of semi-manufactured goods and to be assisted by advanced automatic control technique, the steady and homogeneous quality can be obtained. It can be seen that the on-line detection of extracting process plays an important role in the development of Chinese patent medicines industry. In this paper, the design and implement of a traditional Chinese medicine extracting process monitoring experiment system which is based on PROFIBUS-DP field bus, OPC, and Internet technology is introduced. The system integrates intelligence node which gathering data, superior sub-system which achieving figure configuration and remote supervisory, during the process of traditional Chinese medicine production, monitors the temperature parameter, pressure parameter, quality parameter etc. And it can be controlled by the remote nodes in the VPN (Visual Private Network). Experiment and application do have proved that the system can reach the anticipation effect fully, and with the merits of operational stability, real-time, reliable, convenient and simple manipulation and so on.

  9. The mechanisms in treatment of acute pancreatitis by traditional Chinese medicine

    Institute of Scientific and Technical Information of China (English)

    Xiping Zhang; Ying Wang; Yan Shi

    2006-01-01

    As common acute abdomen, most of acute pancreatitis(AP) are self-restricted. Only a few patients may develop into worse state with local complications or organ failures, and finally neastic acute pancreatitis (NAP). With the change of people's dietaries, cholelithiasis morbidity and popularization of wine in recent years, the number of AP patients has increased.Although people conducted enormous studies on pathogenesis of AP and brought forward many be valuable theories, yet the exact mechanism is still unclear by far. There are many therapies of AP which should be unexceptionally classified as operative therapy and non-operative therapy. With the increasing understanding of the disease in recent years, we found many defects of operation and good therapeutic effects of traditional Chinese medicine in AP. Traditional Chinese medicine as an auxiliary therapy has been generally paid close attention in clinical practices. Traditional Chinese medicine is a treasure-house of China. This article summarizes the main mechanisms of AP treatment by traditional Chinese medicine and the progress of laboratory studies. It aims to help people recognize the multiple-target treatment effects and conspicuous efficacy of traditional Chinese medicine and promote the popularization of traditional Chinese medicine in AP treatment.

  10. Gamma amino butyric acid accumulation in medicinal plants without stress

    Directory of Open Access Journals (Sweden)

    P Anju

    2014-01-01

    Results and Conclusion: Among the screened medicinal plants, Zingiber officinale and Solanum torvum were found to have GABA. The percentage of GABA present in Z. officinale and S. torvum were found to be 0.0114% and 0.0119%, respectively. The present work confirmed that among the selected CNS active medicinal plants, only two plants contain GABA. We found a negative correlation with plant having CNS activity and accumulation of GABA. The GABA shunt is a conserved pathway in eukaryotes and prokaryotes but, although the role of GABA as a neurotransmitter in mammals is clearly established, its role in plants is still vague.

  11. Quality and safety of Chinese herbal medicines guided by a systems biology perspective

    NARCIS (Netherlands)

    Wang, J.; Heijden, R. van der; Spruit, S.; Hankermeier, T.; Chan, K.; Greef, J. van der; Xu, G.; Wang, M.

    2009-01-01

    Chinese herbal medicines, often referred as Chinese materia medica (CMM), are comprised of a complex multicomponent nature. The activities are aimed at the system level via interactions with a multitude of targets in the human body. This review aims at the toxicity aspects of CMM and its preparation

  12. Meeting Minutes of International Conference on Prevention and Treatment of Acquired Immune Deficiency Syndrome with Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    LI Yong; WANG Jie; LIN Hong-sheng; WU Xin-fang; LIU Jie; TANG Yan-li; NAN Ji-hong

    2011-01-01

    @@ The International Conference on Prevention and Treatment of Acquired Immune Deficiency Syndrome (AIDS) with Chinese Medicine (CM) was held in Beijing International Hotel from October 16to 17,2010.It was cosponsored by Guang'anmen Hospital,China Academy of Chinese Medical Sciences (CACMS),and the First Affiliated Hospital of Henan University of Traditional Chinese Medicine.

  13. [Safety and risk factor analysis on Polygoni Multiflori Radix base on ancient traditional Chinese medicine literatures].

    Science.gov (United States)

    Song, Hai-bo; Du, Xiao-xi; Guo, Xiao-xin; Ren, Jing-tian; Yang, Le; Pang, Yu

    2015-03-01

    Traditional Chinese medicine Polygoni Multiflori Radix is dried roots of Polygonaceae Polygortum multiflorum Thunb. Its clinical application records were first discovered in literatures of the Tang dynasty. The origins, efficacy, toxicity, processing and taboos of Polygoni Multiflori Radix have been discussed in many ancient herb literatures. In recent years, with the increase in the public awareness in health, Polygoni Multiflori Radix admits preparations have been more widely applied in the treatment and prevention of diseases. However, there have been more and more reports about Polygoni Multiflori Radix induced liver injury, the safety of Polygoni Multiflori Radix has increasingly attracted attention of the society. In this paper, the authors summarized and analyzed the toxicity and medication risk factors of Polygoni Multiflori Radix recorded in ancient herb literatures, and proposed that more attention shall be given to the effect of the planting and processing methods on the components and toxicity of Polygoni Multiflori Radix in safety studies, which provides clues for the further studies.

  14. Typical Microstructures of Chinese Medicines with X-Ray Microscopy in Phase Contrast

    Institute of Scientific and Technical Information of China (English)

    WEI Xun; XIAO Ti-Qiao; LIU Li-Xiang; DU Guo-Hao; CHEN Min; LUO Yu-Yu; XU Hong-Jie

    2005-01-01

    @@ Due to the low absorption contrast of plant tissues, traditional x-ray radiography has not been included in the microscopic techniques used in the identification of traditional Chinese medicines (TCMs). With the development of x-ray phase contrast imaging (XPCI) in recent years, weakly absorbing materials could also be imaged by xrays. Here we investigate microstructures of TCMs utilizing XPCI based on a nano-focus x-ray tube. The results demonstrated that XPCI is capable of revealing the microstructures of TCMs used as judging criteria in the identification of TCMs. The major advantages of the new method are nondestructivity, no special demand for sample preparation and suitability for thick samples.

  15. [Study on characteristics of pharmacological effects of traditional Chinese medicines distributing along stomach meridian based on medicinal property combination].

    Science.gov (United States)

    Zhang, Bai-Xia; Gu, Hao; Guo, Hong-Ling; Ma, Li; Wang, Yun; Qiao, Yan-Jiang

    2014-07-01

    At present, studies on traditional Chinese medicine (TCM) properties are mostly restricted to a single or two kinds of medicinal properties, but deviated from the holism of the theoretical system of TCMs. In this paper, the characteristics of pharmacological effects of different property combinations of TCMs distributing in the stomach meridian were take as the study objective. The data of properties of TCMs distributing in the stomach meridian was collected from the Pharmacopoeia of the People's Republic of China (2005). The data of pharmacological effects of TCMs distributing in the stomach meridian was collected from all of literatures recorded in Chinese Journal Full-text Database (CNKI) since 1980, Science of Chinese Materia Medica (Yan Zhenghua, People's Medical Publishing House, 2006) and Clinical Science of Chinese Materia Medica (Gao Xuemin, Zhong Gansheng, Hebei Science and Technology Publishing House, 2005). The corresponding pharmacological effects of property combinations of TCMs distributing in the stomach meridian was mined by the method of association rules. The results of the association rules were consistent with the empirical knowledge, and showed that different medicinal property combinations had respective pharmacological characteristics, including differences and similarities in pharmacological effects of different medicinal property combinations. Medicinal property combinations with identical four properties or five tastes showed similar pharmacological effects; whereas medicinal property combinations with different four properties or five tastes showed differentiated pharmacological effects. However, medicinal property combinations with different four properties or five tastes could also show similar pharmacological effects. In this study, the medicinal property theory and the pharmacological effects of TCMs were combined to reveal the main characteristics and regularity of pharmacological effects of TCMs distributing in the stomach meridian

  16. Screening and antibacterial activity analysis of some important medicinal plants

    OpenAIRE

    G. Senthilmurugan Viji; B. Vasanthe; Kuru Suresh

    2013-01-01

    The screening and study of five different plant specimens belonging to different families for phytochemical constituents was performed using generally accepted laboratory technique for qualitative determinations. The constituents screened were saponins, combined anthraquinones, terpenoids, flavonoids, carotenoids, steroids, xantho proteins, couramins, alkaloids, quinones, vitamin C. The distribution of these constituents in the plant specimens were assessed and compared. The medicinal plant s...

  17. [The apprentice education system of Chinese medicinal industry in modern Kunming].

    Science.gov (United States)

    Yang, Zhuqing

    2015-07-01

    In the late Qing Dynasty, following the appearance of the Chinese medicinal materials industry trade association of Kunming, the "master agreement" as a professional regulation, also implemented, marking the beginning of the contractualization and institutionalization of apprentice education in Yunnan. The contents and implementation of the "master agreement" was organized by the Chinese medicinal materials industry trade association of Kunming and its craft union. The apprentice education in Kunming traditional Chinese medicinal industry has the following characteristics: expanding the source of talent; adepting at agricultural production of the accorded apprentice; conforming to the conditions of human manipulation of Chinese traditional medicine; being in line with the characteristics and rules of Chinese medicine skills taught by oral narration and tacit understanding; unity of the medical and pharmaceutical professionals; and non-governmental organization. Apprentice training had trained a number of medical talents, and promoted the transformation of manual workshop to industrialization in Kunming. Apprentice education had catalyzed the establishment of specialized shops selling patent medicines exclusively to separated from those running both crude drugs and patent medicines, to form a set of effective teaching system, thus exerting profound influence on later generations. PMID:26815024

  18. Retinitis Pigmentosa Treatment with Western Medicine and Traditional Chinese Medicine Therapies.

    Science.gov (United States)

    Xu, Jian; Peng, Qinghua

    2015-01-01

    Current management of retinitis pigmentosa (RP) includes an attempt at slowing down the degenerative process through therapies that use either Western or traditional Chinese medicine (TCM). Novel therapies in Western medicine (WM) include use of tailor-made gene therapy, transplantation of stem cells, or neuroprotection treatment. TCM treatment includes two major approaches. These are orally applied herbal decoctions and acupuncture. In fact, all TCM treatments are based on the differentiation of a symptom-complex, which is the characteristic essence of TCM. Thus, diagnosed RP may be treated via the liver, the kidney, and the spleen. The principle behind these treatments is to invigorate the blood and brighten the eyes by toning up the liver and the kidney. Also treatments to cope with deficiencies in the two concepts that are unique and fundamental to TCM are considered: Qi or "vital energy" and Yin and Yang or the harmony of all the opposite elements and forces that make up existence. In particular, the Qi deficiency that results from blood stasis is addressed in these treatments. This paper also puts forward the existing problems and the prospect of the future development on integrating TCM with WM. PMID:26124961

  19. [Medicinal plants in cancer patients: current practices and evaluation data].

    Science.gov (United States)

    Huet, Matthieu

    2013-05-01

    Many complementary and alternatives medicines are offered to patients with cancer. Among them, herbal medicines have a substantial place. These plants are mainly used to reduce adverse effects of anticancer treatments and for specific anticancer properties. Our review shows that only few clinical data support medicinal plants effectiveness in cancer patients. Arguments rely mainly on usual indications and pharmacological data for minimization of treatments toxicity while for the anticancer properties, on epidemiological and preclinical data. To inform and counsel patients and people around, healthcare professionals need to evaluate benefit-risk balance on evidence-based information. Because the medical decision should be shared with the patient, his beliefs and preferences have to be considered. When no adverse effect or drug interaction is associated with herbal medicine, we state that their use is acceptable. This paper discuss of potential risk and benefit of the most used medicinal plants by cancer patients.

  20. Efforts on conservation and sustainable use of medicinal plants of Pakistan

    International Nuclear Information System (INIS)

    Since the beginning of civilization, and perhaps as early as Neanderthal man, people have used plants as medicine. Evidence indicates that people used plants to cure themselves, e.g. Chinese Emperor (2800 BC); Babylon (1770 BC); Ancient Egypt (1550 BC). Islamic and Indian physicians also wrote many works prior to 1100 AD and the Seals from the Harappan site in Pakistan (2000 BC) also indicate use of plants. New aspects of medicinal plants need to be studied. For example, we should address the question why plant diversity declines, when plants with weedy traits become more abundant. This is consequently followed by, species that have traits permitting their persistence in degraded and species-poor cosystems which are likely to carry high pathogen and vector burdens. Indigenous communities of Pakistan play a vital role in conservation of medicinal plants. Intentionally or unintentionally, people have evolved strategies for doing so in the form of rituals, beliefs and taboos. Various traditional harvesting methods described in one of the study suggest that they were efficient to utilize the natural resources. Our efforts are towards not only providing food security, nutrition and health care to the tribal people, but also to recover, record and diffuse local botanical knowledge and wisdom. (author)

  1. Medicinal plants for helminth parasite control: facts and fiction.

    Science.gov (United States)

    Athanasiadou, S; Githiori, J; Kyriazakis, I

    2007-10-01

    The use of medicinal plants for the prevention and treatment of gastro-intestinal parasitism has its origin in ethnoveterinary medicine. Although until recently the majority of the evidence on the antiparasitic activity of medicinal plants was anecdotal and lacked scientific validity, there is currently an increasing number of controlled experimental studies that aim to verify and quantify such plant activity. There are indeed a large number of plants whose anthelmintic activity has been demonstrated under controlled experimentation, either through feeding the whole plant or administering plant extracts to parasitised hosts. However, contrary to traditional expectation, there are also a great number of plants with purported antiparasitic properties, which have not been reproduced under experimental conditions. In this paper, we discuss the source of such inconsistencies between ethnoveterinary wisdom and scientific experimentation. We focus on the strengths and weaknesses of the existing methodologies used in the controlled studies to determine the activity of antiparasitic plants. We discuss issues like the seasonal and environmental variability of the plant composition, and how this can affect their antiparasitic properties and highlight the importance of identifying the mechanisms of action of such plants and the target parasite species. In addition to their antiparasitic properties, medicinal plants may also have anti-nutritional properties, which can affect animal performance and behaviour. For this reason, we emphasise the need for considering additional dimensions when evaluating medicinal plants. We also question whether using similar criteria as those used for the evaluation of anthelmintics is the way forward. We propose that a holistic approach is required to evaluate the potential of medicinal plants in parasite control and maximise their benefits on parasitised hosts. PMID:22444894

  2. Observations on plant usage in Xhosa and Zulu medicine

    Directory of Open Access Journals (Sweden)

    A. Hutchings

    1989-12-01

    Full Text Available The holistic concept of Xhosa and Zulu traditional medicine and some differences from Western orthodox practice are briefly outlined. The transmission of herbal knowledge within various social groups is outlined. The background, training and some procedures followed by five of the informants are discussed. Plant characteristics that may be seen, felt, smelled or tasted are considered as possible determinants of usage. The form of plant parts accounts for some usage in the more magically orientated medicines whereas colour, texture or the production of froth may signal the presence of medicinally active components such as tannin, mucilage and saponin. The role of plants producing a milky latex is discussed. Vesicant or irritant properties are utilized in septic or inflammatory conditions. Aromatic plants are used for respiratory or digestive disorders and pungent-smelling plants are used in the treatment of catarrh and some stress-related disorders. Bitter or sour- tasting plants may be used as an aid to digestion or serve a deterrent function. Parallel usage of some related plants in African and European herbal practice indicates that appropriate usage may be widely determined by easily discerned plant characteristics. Two herbal medicinal recipes recorded by the author and a list of medicinal plants collected in Transkei are presented.

  3. Using the Theory of Planned Behaviour to Explain Use of Traditional Chinese Medicine among Hong Kong Chinese in Britain

    Directory of Open Access Journals (Sweden)

    Tina L. Rochelle

    2015-01-01

    Full Text Available The UK Chinese are known for their underutilisation of western healthcare services. Reasons for this underutilisation are complex. The Theory of Planned Behaviour (TPB is a widely used model of social cognition, which in the present study is being applied to traditional Chinese medicine (TCM utilisation and satisfaction with TCM services. Two hundred and seventy-two UK Chinese aged between 15 and 91 years (M=46.55; SD = 18.53 enrolled in the study. TCM utilisation was associated with gender, age, cultural attachment, and subjective norms. TCM users were more likely to be female and older and have a strong attachment to Chinese culture, and be influenced by the views of important others. Findings highlight the potential of the TPB in exploring TCM utilisation, whilst also throwing light on other factors influential in the use of TCM and satisfaction with TCM service provision among Chinese in the UK.

  4. Using the Theory of Planned Behaviour to Explain Use of Traditional Chinese Medicine among Hong Kong Chinese in Britain.

    Science.gov (United States)

    Rochelle, Tina L; Shardlow, Steven M; Ng, Sik Hung

    2015-01-01

    The UK Chinese are known for their underutilisation of western healthcare services. Reasons for this underutilisation are complex. The Theory of Planned Behaviour (TPB) is a widely used model of social cognition, which in the present study is being applied to traditional Chinese medicine (TCM) utilisation and satisfaction with TCM services. Two hundred and seventy-two UK Chinese aged between 15 and 91 years (M = 46.55; SD = 18.53) enrolled in the study. TCM utilisation was associated with gender, age, cultural attachment, and subjective norms. TCM users were more likely to be female and older and have a strong attachment to Chinese culture, and be influenced by the views of important others. Findings highlight the potential of the TPB in exploring TCM utilisation, whilst also throwing light on other factors influential in the use of TCM and satisfaction with TCM service provision among Chinese in the UK. PMID:26504477

  5. Traditional home gardens: A preserve of medicinal plants

    Directory of Open Access Journals (Sweden)

    Sangeeta Bajpai

    2013-06-01

    Full Text Available Traditional home gardens have been described as man-managed ecosystems with high energy subsidy, complex structure, and multiple functions. These have been reported as treasure trove of a rich biodiversity of plant species including medicinal plants used for traditional home remedies of various ailments. A review of research work on the status of medicinal plants in traditional rural home gardens is presented with the objective to explore them as potential preservation site for medicinal plants. From the available literature it can be ascertained that these traditional rural home gardens can be a suitable site for conservation, propagation, and expansion of medicinal plants that form the backbone of the traditional medicine system and are fast dwindling due to over exploitation and development pattern. Widely reported presence in rural home gardens of medicinal plant species, such as, Adhatoda vasica, Nees., Aloe vera, Mill., Asparagus racemosus, Willd., Chlorophytum tuberosum, Baker., Curcuma angustifolia, Roxb., Dioscorea bulbifera, L., Dioscorea hispida, Dennst., Emblica officinalis, Gaertn., Gymnema sylvestre, Br., Rauwolfia serpentina, Benth., Terminalia arjuna, (Roxb. Wight. and Arn., Tinospora cordifolia, Miers., that are considered endangered is a further confirmation of this belief that traditional rural home gardens can be a good conservation site for domestication and conservation of these plant species.

  6. Comparison on Temperament Theory between Traditional Chinese Medicine and Modern Psychology

    Institute of Scientific and Technical Information of China (English)

    SHI Le

    2002-01-01

    This study has explained and compared temperament theory between traditional Chinese medicine and modernrn psychology on five aspects of concept, characteristics, classification, influential factors and practical significance. And we thought that this study had guiding effect on clinical practice under the new medicine model.

  7. Integrative Chinese and Western Medicine Approach In Treating 64 Patients with Anovular Infertility

    Institute of Scientific and Technical Information of China (English)

    严凤; 张继华; 李瑞芳; 宋兰萍

    2003-01-01

    @@ Sixty-four women with anovular infertility were treated with the integrative Chinese and western medicine (ICWM) approach in our hospital from December 1997 to December 1998. Compared them with 50 women who were treated with Western Medicine (WM) alone, the difference was significant, the report is as follows.

  8. [Treatment of type 2 diabetes mellitus oral Chinese patent medicine literature metrology analysis].

    Science.gov (United States)

    Cui, Tong-hua; Li, Yuan-yuan

    2012-09-01

    The CBM, CNKI database 1979-2012 included oral Chinese patent medicine treatment diabetes literature, and the literature published time, periodical distribution, sources of literature and statistical analysis, to explore the treatment of type 2 diabetes medicine clinical literature distribution law and development trend, as in diabetes research related to the clinical and scientific research personnel to provide reference. PMID:23236770

  9. MEDICINAL PLANTS WITH POTENTIAL ANTICANCER ACTIVITIES: A REVIEW

    Directory of Open Access Journals (Sweden)

    Narah Merina

    2012-06-01

    Full Text Available Plants have been the beacon of therapeutic sources for curing diseases from times immemorial. Medicinal plants with their isolated lead molecules are also used as an alternative medicine for treating neoplastic cells. Neoplastic cells are the anomalous proliferation of cells in the body which cause cancer. Diverse efficient compounds derived from natural products have been isolated as anticancer agents. These chemical compounds are formulated with a view to create effective drugs against cancer. Some of the lead molecules isolated from different medicinal plants are already in use to treat cancer and chemotherapeutic side effects. These potential and successful anticancer molecules include Vincristine, Vinblastin, Taxol, Camptothecin and Podophyllotoxin. This paper deals with the selective medicinal plants having anticancer properties which could be further designed to produce cancer curing drugs.

  10. Tonic Herbs and Herbal Mixtures in Chinese Medicine

    Directory of Open Access Journals (Sweden)

    Thomas Efferth

    2016-01-01

    Full Text Available This review results from a PubMed-based data-mining of scientific literature concerning typical tonic herbs and formulas of Chinese herbal medicine and their application principle under the theory of CM. We have focused on two aspects of tonic activity: body tonification against qi气-, blood血-, yin阴- and yang阳-deficiency, respectively, and organ (Zang 脏and Fu腑 tonification against heart-, liver-, spleen/stomach-, lung-, and kidney-deficiency, respectively. Body-tonifying herbs are: Astragalus Membranaceus Radix (Huang-qi黄芪 and Panax Ginseng Radix (Ren-shen人参 for qi-tonification; Angelicae Sinensis Radix (Dang-gui当归 and Rehmannia Glutinosa Radix Preparata (Shu-di熟地 for blood-tonification; Ophiopogon Japonicus Radix (Mai-dong麦冬 and Scrophularia Ningpoensis Radix (Xuan-shen玄参 for yin-deficiency; Myristica Fragrans Semen (Rou-dou-kou肉豆蔻 and Psoralea Corylifolia Fructus (Bu-gu-zhi补骨脂 for yang-deficiency. The corresponding CM formulas are: Bu-zhong-yi-qi decoction (补中益气汤 for qi-tonification; Si-wu decoction (四物汤 for blood-tonification; Zeng-ye decoction (增液汤 for yin-tonification; Si-shen pill (四神丸 for yang-tonification. Organ-tonifying herbs are: Glycyrrhizae Uralensis Radix Preparata (Zhi-gan-cao炙甘草 and Rehmannia Glutinosa Radix (Di-huang地黄 for heart-tonification; Lycium Barbarum Fructus (Gou-qi-zi枸杞子 and Angelicae Sinensis Radix (Dang-gui当归 for liver-tonification; Panax Ginseng Radix (Ren-shen人参 and Atractylodis Macrocephala Rhizoma (Bai-zhu白术 for spleen/stomach-tonification; Panax Ginseng Radix (Ren-shen人参 and Astragalus Membranaceus Radix (Huang-qi黄芪 for lung-tonification; Cornus Officinalis Fructus (Shan-zhu-yu山茱萸 and Dioscorea Opposite Rhizoma (Shan-yao山药 for kidney-tonification. The corresponding CM formulas are: Zhi-gan-cao decoction (炙甘草汤 for heart-tonification; Yi-guan decoction (一贯煎 for liver

  11. Multimedia-based Medicinal Plants Sustainability Management System

    Directory of Open Access Journals (Sweden)

    Zacchaeus Omogbadegun

    2011-09-01

    Full Text Available Medicinal plants are increasingly recognized worldwide as an alternative source of efficacious and inexpensive medications to synthetic chemo-therapeutic compound. Rapid declining wild stocks of medicinal plants accompanied by adulteration and species substitutions reduce their efficacy, quality and safety. Consequently, the low accessibility to and non-affordability of orthodox medicine costs by rural dwellers to be healthy and economically productive further threaten their life expectancy. Finding comprehensive information on medicinal plants of conservation concern at a global level has been difficult. This has created a gap between computing technologies' promises and expectations in the healing process under complementary and alternative medicine. This paper presents the design and implementation of a Multimedia-based Medicinal Plants Sustainability Management System addressing these concerns. Medicinal plants' details for designing the system were collected through semi-structured interviews and databases. Unified Modelling Language, Microsoft-Visual-Studio.Net, C#3.0, Microsoft-Jet-Engine4.0, MySQL, Loquendo Multilingual Text-to-Speech Software, YouTube, and VLC Media Player were used.

  12. Traditional medicines in Africa: an appraisal of ten potent african medicinal plants.

    Science.gov (United States)

    Mahomoodally, M Fawzi

    2013-01-01

    The use of medicinal plants as a fundamental component of the African traditional healthcare system is perhaps the oldest and the most assorted of all therapeutic systems. In many parts of rural Africa, traditional healers prescribing medicinal plants are the most easily accessible and affordable health resource available to the local community and at times the only therapy that subsists. Nonetheless, there is still a paucity of updated comprehensive compilation of promising medicinal plants from the African continent. The major focus of the present review is to provide an updated overview of 10 promising medicinal plants from the African biodiversity which have short- as well as long-term potential to be developed as future phytopharmaceuticals to treat and/or manage panoply of infectious and chronic conditions. In this endeavour, key scientific databases have been probed to investigate trends in the rapidly increasing number of scientific publications on African traditional medicinal plants. Within the framework of enhancing the significance of traditional African medicinal plants, aspects such as traditional use, phytochemical profile, in vitro, in vivo, and clinical studies and also future challenges pertaining to the use of these plants have been explored.

  13. Medicinal Plants Traditionally Used in Mali for Dysmenorrhea

    OpenAIRE

    Sanogo, Rokia

    2011-01-01

    Dysmenorrhea is painful menstrual cramps, which negatively impacts the quality of life of a large percentage of the world's female population in reproductive age. The paper reviews the plants used in the Malian traditional medicine for the treatment of dysmenorrhea. Some medicinal plants were effective for treatments of dysmenorrhea with minimal side effects. Conventional therapy for dysmenorrhea, which usually includes non-steroidal anti-inflammatory drugs (NSAIDs), provides symptomatic reli...

  14. Potential Anti-Arthritic Agents From Indian Medicinal Plants

    OpenAIRE

    Samrat Chauhan; Lalit Kishore; Navpreet Kaur; Randhir Singh

    2015-01-01

    Traditional medicines are used globally for management of rheumatoid arthritis since prehistoric times. This review emphasizes on the Indian medicinal flora and their traditional utilization in the management of rheumatoid arthritis. Peer reviewed articles from the last three decades and the classical textbooks were examined for bibliographic investigation. Plant extract traditionally used for ameliorating arthritic condition have been studied in the present review. 124 plants, traditionally ...

  15. MEDICINAL PLANTS WITH POTENTIAL ANTICANCER ACTIVITIES: A REVIEW

    OpenAIRE

    Narah Merina; Kalita Jogen Chandra; Kotoky Jibon

    2012-01-01

    Plants have been the beacon of therapeutic sources for curing diseases from times immemorial. Medicinal plants with their isolated lead molecules are also used as an alternative medicine for treating neoplastic cells. Neoplastic cells are the anomalous proliferation of cells in the body which cause cancer. Diverse efficient compounds derived from natural products have been isolated as anticancer agents. These chemical compounds are formulated with a view to create effective drugs against can...

  16. Database on pharmacophore analysis of active principles, from medicinal plants

    OpenAIRE

    Pitchai, Daisy; Manikkam, Rajalakshmi; Rajendran, Sasikala R; Pitchai, Gnanamani

    2010-01-01

    Plants continue to be a major source of medicines, as they have been throughout human history. In the present days, drug discovery from plants involves a multidisciplinary approach combining ethnobotanical, phytochemical and biological techniques to provide us new chemical compounds (lead molecules) for the development of drugs against various pharmacological targets, including cancer, diabetes and its secondary complications. In view of this need in current drug discovery from medicinal plan...

  17. Applications of HPLC/MS in the analysis of traditional Chinese medicines%Applications of HPLC/MS in the analysis of traditional Chinese medicines

    Institute of Scientific and Technical Information of China (English)

    Miao Li; Xiao- Fang Hou; Jie Zhang; Si-Cen Wang; Qiang Fu; Lang- Chong He

    2011-01-01

    In China, traditional Chinese medicines (TCMs) have been used in clinical applications for thousands of years. The successful hyphenation of high-performance liquid chromatography (HPLC) and mass spectrometry (MS) has been applied widely in TCMs and biolo

  18. Review of the use of botanicals for epilepsy in complementary medical systems--Traditional Chinese Medicine.

    Science.gov (United States)

    Xiao, Fenglai; Yan, Bo; Chen, Lei; Zhou, Dong

    2015-11-01

    In traditional Chinese medicine, botanical remedies have been used for centuries to treat seizures. This review aimed to summarize the botanicals that have been used in traditional Chinese medicine to treat epilepsy. We searched Chinese online databases to determine the botanicals used for epilepsy in traditional Chinese medicine and identified articles using a preset search syntax and inclusion criteria of each botanical in the PubMed database to explore their potential mechanisms. Twenty-three botanicals were identified to treat epilepsy in traditional Chinese medicine. The pharmacological mechanisms of each botanical related to antiepileptic activity, which were mainly examined in animal models, were reviewed. We discuss the use and current trends of botanical treatments in China and highlight the limitations of botanical epilepsy treatments. A substantial number of these types of botanicals would be good candidates for the development of novel AEDs. More rigorous clinical trials of botanicals in traditional Chinese medicine for epilepsy treatment are encouraged in the future. This article is part of a Special Issue entitled "Botanicals for Epilepsy".

  19. Turkish folk medicinal plants, VIII: Lalapaşa (Edirne)

    OpenAIRE

    Ertan Tuzlacı; Duygu Fatma Alparslan İşbilen; Gizem Bulut

    2014-01-01

    ABSTRACT: In this study, the folk medicinal plants of Lalapaşa (Edirne) were researched.During the field works, the information were obtained from local healers, experienced adultsand patients by personal interviews and the specimens of the plants were collected. Accordingto the results of the identifications of the specimens, 55 plant taxa are used in therapy inLalapaşa. These are presented in a table in the text. Among them 44 taxa are wild and 11 taxaare cultivated plants. The folk medicin...

  20. MEDICINAL PLANTS OF RAJASTHAN (INDIA WITH ANTIDIABETIC POTENTIAL

    Directory of Open Access Journals (Sweden)

    Batra Shikha

    2011-03-01

    Full Text Available Rajasthan has a rich heritage of traditional system of medicine and many medicinally useful plants are found growing wildly because of vast area and variety of agro-climatic conditions. These plants are being used for the treatment of many human ailments including diabetes. Plants that are specifically employed for the treatment of diabetes are Acacia nilotica, Acacia senegal, Aegle marmelos, Calotropis procera, Capparis deciduas, Cassia auriculata, Cassia sophera, Cayratia trifolia, Cyamopsis tetragonoloba, Dalbergia sisso, Gymnema sylvestre, Momordica charantia, Syzygium cumini, Withania somnifera. This article aims to provide a comprehensive review on the some plants of Rajasthan having antidiabetic potential.

  1. [Herbal textual research on origin and development of traditional Chinese medicine "duhuo" and "qianghuo"].

    Science.gov (United States)

    Shan, Feng; Yuan, Yuan; Hao, Jin-Da; Huang, Lu-Qi

    2014-09-01

    To clarify the origin and development of the traditional Chinese medicine "Duhuo" and "Qianghuo" with medicinal literatures. Medical literatures of past dynasties were analysed and combined with the modern material. The "Duhuo" in Herbal writing Shen Nong Ben Cao Jing include traditional Chinese medicine "Duhuo" and "Qianghuo", "Qianghuo" was separated from "Duhuo" due to the distinguish of clinical application. The origin of "Qianghuo" is Notopterygium incisum and N. forbesii, However, The origin of "Duhuo" is very complex, Angelica pubescens f. biserrata as authentic "Duhuo" was used from Song Dynasty. "Qianghuo" was originated from "Duhuo". PMID:25522638

  2. Marketing strategy for a traditional Chinese medicine (TCM) clinic in Vancouver

    OpenAIRE

    Janjua, Qaiser Rashid

    2006-01-01

    Complementary and Alternative Medicine (CAM) has gained worldwide acceptance in the recent past. Apart from all other modalities of CAM, Traditional Chinese Medicine (TCM) has gained enormous interest globally. TCM has become a mainstream medicine in several underdeveloped countries and is rapidly gaining recognition in developed countries such as in the U.S and especially Canada. British Columbia is the only jurisdiction in North America that officially recognizes TCM. Consequently, the loca...

  3. 中药退热机制研究进展%Research Progress of Antipyretic Mechanism of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    韩庆荣; 张永科; 刘明云

    2013-01-01

    Objective:Tò summarize the antipyretic mechanism of traditional Chinese medicine.Methods:Retrieve and analyze relevant literature about antifebrile by traditional Chinese medicine.Results:Single traditional Chinese medicine and Chinese medicine formula have certain superiority in the treatment of febrile disease.Chinese medicine for antipyretic is variety in resources.Conclusion:The antifebrile effect of traditional Chinese medicine is better.%目的:探讨中药的退热机制.方法:检索有关中医药退热方面的文献,并进行分析.结果:单味中药、中药组方对于发热疾病的治疗有一定的优越性,中药解热药种类繁多,资源丰富.结论:中医药退热效果较好.

  4. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Ming; Wang, Ning; Tan, Hor Yue [School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong (China); Tsao, Sai-Wah [Department of Anatomy, Li KaShing Faculty of Medicine, The University of Hong Kong, Hong Kong (China); Feng, Yibin, E-mail: yfeng@hku.hk [School of Chinese Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong (China)

    2015-08-24

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC). In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products.

  5. The Mechanism for the Effect of Chinese Medicine on Strait Episode of Complex Diseases.

    Science.gov (United States)

    Han, Jing-Yan

    2016-01-01

    Complex diseases always involve some strait episode, such as myocardial hypertrophy and fibrosis caused by hypertension, microcirculation dysfunction and injury in heart, brain, lever, and intestine following ischemia and reperfusion, endotoxin induced multiorgan injury, and recovery after intestinal mucosa damage, for which intervention by a single medicine remains unsatisfied in clinic.Chinese medicine has been applied in clinic for more than two thousand years, which presents as a healthcare system using compound formula preparation, treatment based on syndrome differentiation and individualization thus has advantage in dealing with strait episode of complex diseases. However, the mechanism underlying Chinese medicine is not fully understood up till now.This report will explain the mechanisms underlying the beneficial role of Chinese medicine in therapy of strait episode of complex diseases based on the resent outcomes in study of aforementioned complex diseases. The speaker, using the theory of blood stasis and activating blood to remove stasis in Chinese medicine, classified microcirculation dysfunction induced by different causes, such as ischemia and reperfusion, stress, LPS, common cold, investigated the pathogenesis and progressing of each of which. Furthermore, the report explored the material basis and mechanism for compound formula of Chinese medicine with potential of tonifying Qi and activating blood, removing heat to cool blood, identified the ingredient in the compound formula responsible for respective effect.(Presented at the 1920th Meeting, June 3, 2016). PMID:27349663

  6. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    Directory of Open Access Journals (Sweden)

    Ming Hong

    2015-08-01

    Full Text Available In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC. In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products.

  7. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy

    International Nuclear Information System (INIS)

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC). In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products

  8. MicroRNAs and Chinese Medicinal Herbs: New Possibilities in Cancer Therapy.

    Science.gov (United States)

    Hong, Ming; Wang, Ning; Tan, Hor Yue; Tsao, Sai-Wah; Feng, Yibin

    2015-01-01

    In recent decades Chinese medicine has been used worldwide as a complementary and alternative medicine to treat cancer. Plenty of studies have shown that microRNAs (miRNAs) play fundamental roles in many pathological processes, including cancer, while the anti-cancer mechanisms of Chinese medicinal herbs targeting miRNAs also have been extensively explored. Our previous studies and those of others on Chinese medicinal herbs and miRNAs in various cancer models have provided a possibility of new cancer therapies, for example, up-regulating the expression of miR-23a may activate the positive regulatory network of p53 and miR-23a involved in the mechanism underlying the anti-tumor effect of berberine in hepatocellular carcinoma (HCC). In this review, we survey the role of Chinese medicinal herbal products in regulating miRNAs in cancer and the use of mediating miRNAs for cancer treatment. In addition, the controversial roles of herb-derived exogenous miRNAs in cancer treatment are also discussed. It is expected that targeting miRNAs would provide a novel therapeutic approach in cancer therapy by improving overall response and survival outcomes in cancer treatment, especially when combined with conventional therapeutics and Chinese medicinal herbal products. PMID:26305257

  9. Traditional uses of medicinal plants of uzumlu district, erzincan, turkey

    International Nuclear Information System (INIS)

    A list of medicinal plants used by local people in uzumlu district and its villages is presented. This study included the first detailed ethnobotanical survey carried out in Erzincan. The study was conducted during spring and summer periods in 2010 and 2011 through face-to-face interview method to determine the local names, used parts, and medicinal usages of the determined plants. The plant samples collected from the study area were pressed, dried, and labeled according to the herbarium techniques, and identified. Totally 64 plant taxa belonging to 53 genera and 29 families were used by local people for different medicinal purposes in the area. The families including the highest number of taxa were Rosaceae (11 species), Asteraceae (6 species) and Lamiaceae (5 species). The species with the highest number of usage as herbal medicine were Urtica dioica, Anthemis cretica subsp. iberica, Petroselinum crispum,Allium cepa, Rheum ribes, Rosa dumalis subsp. boissieri var. boissieri and Vitis vinifera. Fruits and flowers were the most widely used parts of the plants. Decoction was the main method for using, and the primary therapeutic use of herbal remedies was for the respiratory system diseases such as cold, cough, asthma, and bronchitis.This study was the first carried out on 20 plant taxa used as traditional medicine, and the use of 28 taxa were recorded for the first time in Turkey. For maintaining the knowledge on traditional medicine, urgent studies should be carried out for recording before they have been completely lost. (author)

  10. Treatment of cholecystitis with Chinese herbal medicines: A systematic review of the literature

    Institute of Scientific and Technical Information of China (English)

    Zhi-Yong Dong; Guan-Liang Wang; Xing Liu; Jia Liu; De-Zeng Zhu; Chang-Quan Ling

    2012-01-01

    AIM:To analyze the literature on the use of Chinese herbal medicines for the treatment of cholecystitis.METHODS:The literature on treatment of cholecystitis with traditional Chinese medicines (TCM) was analyzed based on the principles and methods described by evidence-based medicine (EBM).Eight databases including MEDLINE,EMbase,Cochrane Central (CCTR),four Chinese databases (China Biological Medicine Database,Chinese National Knowledge Infrastructure Database,Database of Chinese Science and Technology Periodicals,Database of Chinese Ministry of Science and Technology) and Chinese Clinical Registry Center,were searched.Full text articles or abstracts concerning TCM treatment of cholecystitis were selected,categorized according to study design,the strength of evidence,the first author's hospital type,and analyzed statistically.RESULTS:A search of the literature published from 1977 through 2009 yielded 1468 articles in Chinese and 9 in other languages; and 93.92% of the articles focused on clinical studies.No article was of level I evidence,and 9.26% were of level Ⅱ evidence.The literature cited by Science Citation Index (SCI),MEDLINE and core Chinese medical journals accounted for 0.41%,0.68% and 7.29%,respectively.Typically,the articles featured in case reports of illness,examined from the perspective of EBM,were weak in both quality and evidence level,which inconsistently conflicted with the fact that most of the papers were by authors from Level-3 hospitals,the highest possible level evaluated based on their comprehensive quality and academic authenticity in China.CONCLUSION:The published literature on TCM treatment of cholecystitis is of low quality and based on low evidence,and cognitive medicine may functions as a useful supplementary framework for the evaluation.

  11. ANTIVIRAL POTENTIAL OF MEDICINAL PLANTS: AN OVERVIEW

    OpenAIRE

    Ruwali Pushpa; Rai Nishant; Kumar Navin; Gautam Pankaj

    2013-01-01

    The term ‘Antiviral agents’ has been defined in very broad terms as substances other than a virus or virus containing vaccine or specific antibody which can produce either a protective or therapeutic effect to the clear detectable advantage of the virus infected host. The herbal medicine has a long traditional use and the major advantage over other medicines is their wide therapeutic window with rare side effects. There are some disadvantages of synthetic drugs like narrow therapeutic window...

  12. Some medicinal plants with antiasthmatic potential:a current status

    Institute of Scientific and Technical Information of China (English)

    Dnyaneshwar J Taur; Ravindra Y Patil

    2011-01-01

    Asthma is a common disease that is rising in prevalence worldwide with the highest prevalence in industrialized countries. Asthma affect about 300 million people worldwide and it has been estimated that a further 100 million will be affected by 2025. Since the ancient times, plants have been exemplary sources of medicine. Current asthma therapy lack satisfactory success due to adverse effect, hence patients are seeking complementary and alternative medicine to treat their asthma. Ayurveda and other Indian literature mention the use of plants in various human ailments. India has about 45 000 plant species and among them several thousand are claimed to possess medicinal properties. Researches conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for asthma have shown antiasthmatic, antihistaminic and antiallergic activity. This review reveals that some plants and their extract have antiasthmatic, antihistaminic, anticholinergic and antiallergic activity.

  13. Therapeutic uses of animal biles in traditional Chinese medicine: an ethnopharmacological, biophysical chemical and medicinal review.

    Science.gov (United States)

    Wang, David Q-H; Carey, Martin C

    2014-08-01

    Forty-four different animal biles obtained from both invertebrates and vertebrates (including human bile) have been used for centuries for a host of maladies in traditional Chinese medicine (TCM) beginning with dog, ox and common carp biles approximately in the Zhou dynasty (c. 1046-256 BCE). Overall, different animal biles were prescribed principally for the treatment of liver, biliary, skin (including burns), gynecological and heart diseases, as well as diseases of the eyes, ears, nose, mouth and throat. We present an informed opinion of the clinical efficacy of the medicinal uses of the different animal biles based on their presently known principal chemical components which are mostly steroidal detergent-like molecules and the membrane lipids such as unesterified cholesterol and mixed phosphatidylcholines and sometimes sphingomyelin, as well as containing lipopigments derived from heme principally bilirubin glucuronides. All of the available information on the ethnopharmacological uses of biles in TCM were collated from the rich collection of ancient Chinese books on materia medica held in libraries in China and United States and the composition of various animal biles was based on rigorous separatory and advanced chemical identification techniques published since the mid-20(th) century collected via library (Harvard's Countway Library) and electronic searches (PubMed and Google Scholar). Our analysis of ethnomedical data and information on biliary chemistry shows that specific bile salts, as well as the common bile pigment bilirubin and its glucuronides plus the minor components of bile such as vitamins A, D, E, K, as well as melatonin (N-acetyl-5-methoxytryptamine) are salutary in improving liver function, dissolving gallstones, inhibiting bacterial and viral multiplication, promoting cardiac chronotropsim, as well as exhibiting anti-inflammatory, anti-pyretic, anti-oxidant, sedative, anti-convulsive, anti-allergic, anti-congestive, anti-diabetic and anti

  14. Plant Secondary Metabolites in some Medicinal Plants of Mongolia Used for Enhancing Animal Health and Production

    OpenAIRE

    Makkar, HPS; Norvsambuu, T.; Lkhagvatseren, S.; Becker, K.

    2009-01-01

    The levels and activities of a number of plant secondary metabolites (PSMs) are known to increase in response to increase in stress. The Mongolian plants considered to possess medicinal properties may contain novel compounds since they are exposed to severe conditions; such plants could become good candidates for modern drug discovery programmes. Information on distribution, palatability to livestock and opinion of local people on their nutritive and medicinal values was compiled for 15 plant...

  15. [Construction of Research-Oriented State Key Clinical Department by Highlighting the Characteris- tics and Advantages of Chinese Medicine].

    Science.gov (United States)

    Ma, Shi-yu; Guo, Li-heng; Han, Yun; Li, Jian; Zhang, Min-zhou

    2016-04-01

    As the largest research-oriented specialty department in national traditional Chinese medicine hospitals, the Department of Critical Care Medicine in Guangdong Provincial Hospital of Chinese Medicine insists on the development mode combined with clinical medicine and scientific research. By taking clinical and basic researches for integrative medicine preventing and treating acute myocardial in-farction and sepsis as a breakthrough, authors explored key problems of Chinese medicine in improving the prognosis related diseases and patients' quality of life. In recent 3 years our department has successively become the principal unit of the national key specialties cooperative group of critical care medicine (awarded by State Administration of Traditional Chinese Medicine), the key clinical specialties (awarded by National Health and Family Planning Commission), and Guangzhou key laboratory construction unit, and achieved overall lap in clinical medical treatment, personnel training, scientific research, and social service.

  16. Studies on Treating Eczema by Chinese Herbal Medicine with Anti-Type Ⅳ Allergic Activity

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Objective: To study Chinese herbal prescription for treatment of eczema on the basis of the suppressive effect of Chinese herbal medicine with type Ⅳ allergic reaction. Methods: Various formulae composed of Chinese herbal medicines possessing suppressive effect on murine allergic contact dermatitis were formed following the therapeutic principles of traditional Chinese medicine in treating eczema, and their effect on ear swelling, ear flake weight, dermal inflammatory infiltration cell count and plasma level of calcitonin gene related peptide ( CGRP) were examined in mice with dinitrofluorobenzene induced dermatitis. The prescription, Composite Poria Decoction was formulated and made into granule form, which was used to treat 63 cases of eczema (atopic dermatitis was excluded), and compared with 59 cases treated with antihistaminic that was aimed at the type I allergic reaction. Results: Experimental study showed that all the 4 Chinese prescriptions had the effect of anti-type Ⅳ allergic reaction, among them, the formula for cooling blood and removing Heat, Wind and Dampness evil possessed the most potent effect in suppressing murine dermatitis, and it was also able to up-regulate the plasma CGRP concentration. The clinical cure rate of Composite Poria Granule treatment was 47.6%, and that of the control was 22.0%. The difference was significant between the two groups (u=2.9555, P<0.01). Conclusions: Chinese herbal medicine has the effect of anti-type Ⅳ allergic reaction. Composite Poria Granule has good effect in treating eczema.

  17. Medicinal plants used to treat malaria in Southern Benin

    NARCIS (Netherlands)

    Maesen, van der L.J.G.

    2004-01-01

    People in Benin who cannot resort to allopathic medicines provided by the pharmaceutical industry use many species of plants to alleviate malaria symptoms. Complicated mixtures of different parts of several plant species are employed orally or as a bathing substance. The inventory of 85 species and

  18. Plantas medicinais: cura segura? Medicinal plants: safe cure?

    OpenAIRE

    Valdir F. Veiga Junior; Angelo C. Pinto; Maria Aparecida M. Maciel

    2005-01-01

    This paper reviews the recent literature on synergism, adulteration and risks of using medicinal plants. The use of copaiba and sacaca plants as well as their adulteration and side effects, are also described. In addition, the new regulations on phytotherapeutic registration in Brazil and Europe are discussed.

  19. TREATMENT OF PRIMARY PALPEBRAL RETRACTION WITH ACUPOINT—INJECTION AND CHINESE MEDICINAL HERBS

    Institute of Scientific and Technical Information of China (English)

    朱新民; LiPeifang

    2000-01-01

    In the present paper,the therapeutic effect of combined therapy of acupoint-injection and Chinese medicinal herbs was observed in 59cases of primary palpebral retraction patients.These 59patients were divided into treatment group(n=38,treated with acupoint-injection and Chinese medicinal herbs)and control group(n=21,treated with Chinese medicinal herbs alone).After3 courses of treatment.of the 38cases in treatment group,25(65.8%)were cured,8(21.1%)had marked improement and5(13.2%)had improement;of the 21cases in control group,8(38.1%)were cured,9(42.9%)had marked improement,2(9.5%)had improement6 and2(9.5%)were ineffective.Statistical analysis showed a si9gnificant difference between the two groups in the therapeu-tic effect.The cure rate of experimental group was apparently higher than athat of the control group,i.e.the therapeutic effect of the combined therapy of acupoint-injection and Chinese medicinal herbs was superior to that of Chinese medicinal herbs alone.

  20. Traditional Chinese medicine valuably augments therapeutic options in the treatment of climacteric syndrome.

    Science.gov (United States)

    Eisenhardt, Sarah; Fleckenstein, Johannes

    2016-07-01

    Climacteric syndrome refers to recurring symptoms such as hot flashes, chills, headache, irritability and depression. This is usually experienced by menopausal women and can be related to a hormonal reorganization in the hypothalamic-pituitary-gonadal axis. In Traditional Chinese Medicine, originating 1000s of years ago, above-mentioned symptoms can be interpreted on the basis of the philosophic diagnostic concepts, such as the imbalance of Yin and Yang, the Zang-Fu and Basic substances (e.g. Qi, Blood and Essence). These concepts postulate balance and harmonization as the principle aim of a treatment. In this context, it is not astounding that one of the most prominent ancient textbooks dating back to 500-200 BC, Huang di Neijing: The Yellow Emperor's Classic of Internal Medicine gives already first instructions for diagnosis and therapy of climacteric symptoms. For therapy, traditional Chinese medicine comprises five treatment principles: Chinese herbal medicine, TuiNa (a Chinese form of manual therapy), nutrition, activity (e.g. QiGong) and acupuncture (being the most widespread form of treatment used in Europe). This review provides an easy access to the concepts of traditional Chinese medicine particularly regarding to climacteric syndrome and also focuses on current scientific evidence. PMID:27040419

  1. Screening of Chinese Herbal Medicines Resistant to Chicken Escherichia coli and Infectious Laryngotracheitis Virus

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    [Objective] This study aimed to screen Chinese herbal medicines resistant to Chicken Escherichia coli and infectious laryngotracheitis virus. [Methed] Conven- tional punch method, test tube method and plate dilution method were adopted for in vitro susceptibility test of chicken E, coil strains O5 and O8 using 13 kinds of Chi- nese herbal medicines including Sanguisorba officinalis, Coptis chinensis, Anemar- rhena asphodeloides, Strobilanthes cusia, Agastache rugosa, etc.; chicken embryo inoculation experiment was adopted to screen Chinese herbal medicines resistant to chicken infectious laryngotracheitis virus. [Result] Sanguisorba officinalis, Fructus mume, Rheum officinale, Coptis chinensis, Herba Taraxaci, Anemarrhena asphode- Ioides, Scutellaria baicalensis and Rhizoma Fagopyri Cymosi had ideal antibacterial effect against chicken E. coil strain O5; Sanguisorba officinalis, Fructus mume, Rheum officinale, Coptis chinensis, Herba taraxaci and Rhizoma Fagopyri Cymosi had ideal antibacterial effect against chicken E. coil strain 08; other Chinese herbal medicines showed relatively poor or no antibacterial effect. Results of chicken embryo inoculation experiment showed that nine kinds of Chinese herbal medicines showed relatively strong anti-lLTV effect, including Forsythia suspensa, Radix Isatidis, Fofium isatidis, Flos Ionicerae, Radix codonopsis, Radix astragali, Atractylodes, Radix gly- cyrrhizae, and Pericarpium granati. [Conclusion] The study laid the foundation for fur- ther development of Chinese herbal compound preparations to treat chicken cofibacil- Iosis, infectious laryngotracheitis and other bacterial, viral diseases.

  2. [Application characteristics and situation analysis of volatile oils in database of Chinese patent medicine].

    Science.gov (United States)

    Wang, Sai-Jun; Wu, Zhen-Feng; Yang, Ming; Wang, Ya-Qi; Hu, Peng-Yi; Jie, Xiao-Lu; Han, Fei; Wang, Fang

    2014-09-01

    Aromatic traditional Chinese medicines have a long history in China, with wide varieties. Volatile oils are active ingredients extracted from aromatic herbal medicines, which usually contain tens or hundreds of ingredients, with many biological activities. Therefore, volatile oils are often used in combined prescriptions and made into various efficient preparations for oral administration or external use. Based on the sources from the database of Newly Edited National Chinese Traditional Patent Medicines (the second edition), the author selected 266 Chinese patent medicines containing volatile oils in this paper, and then established an information sheet covering such items as name, dosage, dosage form, specification and usage, and main functions. Subsequently, on the basis of the multidisciplinary knowledge of pharmaceutics, traditional Chinese pharmacology and basic theory of traditional Chinese medicine, efforts were also made in the statistics of the dosage form and usage, variety of volatile oils and main functions, as well as the status analysis on volatile oils in terms of the dosage form development, prescription development, drug instruction and quality control, in order to lay a foundation for the further exploration of the market development situations of volatile oils and the future development orientation. PMID:25522633

  3. Effect of Chinese Medicines on the Subretinal Fluid Absorption after Operation for Retinal Detachment

    Institute of Scientific and Technical Information of China (English)

    YeziLiu

    1995-01-01

    Purpose:To determine the effects of traditional Chinese medicines on subretinal fluld absorption after Operation for retinal detachment.Mehods:Among100eyes with operations fo retinal detachment without drainage of fluid,there were 50eyes in traditional Chinese medicine treatment group and 50eyes in the control group.and there were no significant difference between the two groups in age,myopia and retinal detachment area.We observed the time for the absorption of subretinal fluid and visual acuity improvement aftr the opera-tions for retinal detachment.Results;he result showed that the average time for the absorption of subretinal fluid was14.5days in the traditional Chinese medicine treatment group,21.7days in the control group and the visual acuity was better in the former than in the latter.Conclusions:The taditional Chinese medicine treatment could increase the ab-sorption of subretional fluid,the mechanisms of which may be that Chinese medicines regulated and impved the general blood circulation and local eye blood criculation and the function of blood-retinal barrier so that they increase the out-ward osmotic suction forces of the pigment epithelium.

  4. Plant Sources of Chinese Herbal Remedies: Laboratory Efficacy, Suppression of Meloidogyne javanica in Soil, and Phytotoxicity Assays

    OpenAIRE

    Zasada, I. A.; Ferris, H.; Zheng, L

    2002-01-01

    Extracts of Chinese herbal medicines from plants representing 13 families were tested for their ability to suppress plant-parasitic nematodes. Effective concentration (EC50 and EC90) levels for 18 of the extracts were determined in laboratory assays with Meloidogyne javanica juveniles and all stages of Pratylenchus vulnus. Efficacy of 17 extracts was tested against M. javanica in soil. Generally, EC50 and EC90 values determined in the laboratory were useful indicators for application rates in...

  5. Ontology Mapping of Indian Medicinal Plants with Standardized Medical Terms

    Directory of Open Access Journals (Sweden)

    S. Waheeta Hopper

    2012-01-01

    Full Text Available Problem statement: World Wide Web (WWW consisting large volume of information related with medicinal plants. However health care recommendation with Indian Medicinal Plants becomes complicated because valuable Information about medicinal resources as plants is scattered, in text form and unstructured. Search engines are not quite efficient and require excessive manual processing. Therefore search becomes difficult for the ordinary users to find the medicinal uses of herbal plants from the web. And another problem is that the domain experts could not able to map the medicinal uses of herbal plants with the existing standardized medical terms. Mapping the existing ontology introduces the problem of finding the similarity between the terms and relationships. Finding the solution to perform automatic mapping is another major challenge to be solved. Approach: To address these issues we developed a Knowledge framework for the Indian Medicinal Plants (KIMP. Knowledge framework includes the ontology creation, user interface for querying the system. Jena is used to build semantic web applications with the ontology representation of Resource Description Framework (RDF and Web Ontology Language (OWL. SPARQL Protocol and RDF Query Language (SPARQL is used to retrieve various query patterns. Automated mapping is achieved by considering lexical and edge based relatedness. Results: The user interface is demonstrated for five thousand concepts, which gives the related information from Wikipedia web page in three languages. Mapping recommendation by the lexical similarity Jaccard algorithm gives 27% and Jaro Winkler algorithm gives 60%. Edge based relationship using WuPalmer algorithm gives 93% mapping recommendation. These are analyzed and compared with our algorithm based on WuPalmer gives more specific mapping results than WuPalmer with 71%. Conclusion: Thus it possible to find the specific resultant web page based on the user requirement in three different

  6. Potential Anti-Arthritic Agents From Indian Medicinal Plants

    Directory of Open Access Journals (Sweden)

    Samrat Chauhan

    2015-09-01

    Full Text Available Traditional medicines are used globally for management of rheumatoid arthritis since prehistoric times. This review emphasizes on the Indian medicinal flora and their traditional utilization in the management of rheumatoid arthritis. Peer reviewed articles from the last three decades and the classical textbooks were examined for bibliographic investigation. Plant extract traditionally used for ameliorating arthritic condition have been studied in the present review. 124 plants, traditionally used in the management of arthritis have been recorded. This study reflects the need to explore potential chemical moieties from unexploited plants in arthritic management along with the mechanism of action through which they would act, remain to be studied.

  7. The Medicinal Plant of Mimusops Elengi (Sapodaceae in Antimicrobial Activities

    Directory of Open Access Journals (Sweden)

    Kannadhasan M.

    2016-07-01

    Full Text Available The selected study area for this study is Pachaimalai Hills, situated in Eastern ghats of Tamil Nadu. This study was focussed on the antimicrobial activity of Mimosopselengi, one of the medicinal plant belongs to the family sapotaceae. It is a tropically distributed the highly medicinal plant. Antimicrobial activities and extracts of petroleum ether, Ethyl acetate and methanol were also found to be better with respect to inhibitory function against the two fungal species, Fusarium oxysporum and Aspergillus flavus. The study scientifically validates the use of plant in traditional and ethno medicine. Three solvents such as Petroleum ether, Ethyl acetate and Ethanol were used to take plant extract. These extracts were studied for antimicrobial activity against two gram positive bacterial strains such as Bacillus substilis andBacillus thuriengensis and two gram negative bacterial strains such as Klebsiella pneumonia and Escherichia coli. This study also extended to find antifungal activity against four fungal strains.

  8. MEDICINAL PLANTS USED AS ANTIMICROBIAL AGENTS: A REVIEW

    Directory of Open Access Journals (Sweden)

    Parmar Namita

    2012-01-01

    Full Text Available Infectious diseases are caused by pathogenic microorganisms, such as bacteria, viruses, parasites or fungi. Diseases can spread, directly or indirectly, from one person to another. Infectious diseases are the second leading cause of death worldwide. About one-fourth of all the medicines we use, come from rainforest plants. However, scientific studies have been conducted only to a limited extent with few medicinal plants. The development of bacterial resistance to presently available antibiotics has necessitated the search of new antibacterial agents. In rural and backward area of India, several plants are commonly used as herbal medicine for the treatment of infectious diseases. Four such plants commonly used by the people of the area were screened for potential antibacterial activity.

  9. Radiomodulatory potential of hydroalcoholic extract of a medicinal plant Cynodon dactylon (Family: Poaceae), against radiation-induced cytogenetic damage

    International Nuclear Information System (INIS)

    The exposure of humans to ionizing radiations may be advertently by routine diagnostic and therapeutic purposes or inadvertently during natural, occupational and nuclear accident situations. Therefore, in order to overcome the deleterious biological effects of radiation several chemical agents have been studied for their radioprotective potential. The medicinal plants being one of the resources for such clinically important natural agents, used extensively in several drug discovery related research. Here the radiomodulatory potential of hydroalcoholic extract of a medicinal plant Cynodon dactylon (Family: Poaceae), against radiation-induced cytogenetic damage was analyzed using Chinese hamster fibroblast cells (V79) and human peripheral blood lymphocytes (HPBLs) growing in vitro is reported

  10. Identification of Ornamental Plant Functioned as Medicinal Plant Based on Redundant Discrete Wavelet Transformation

    Directory of Open Access Journals (Sweden)

    Kohei Arai

    2013-03-01

    Full Text Available Human has a duty to preserve the nature. One of the examples is preserving the ornamental plant. Huge economic value of plant trading, escalating esthetical value of one space and medicine efficacy that contained in a plant are some positive values from this plant. However, only few people know about its medicine efficacy. Considering the easiness to obtain and the medicine efficacy, this plant should be an initial treatment of a simple disease or option towards chemical based medicines. In order to let people get acquaint, we need a system that can proper identify this plant. Therefore, we propose to build a system based on Redundant Discrete Wavelet Transformation (RDWT through its leaf. Since its character is translation invariant that able to produce some robust features to identify ornamental plant. This system was successfully resulting 95.83% of correct classification rate.

  11. The microbiome of medicinal plants: diversity and importance for plant growth, quality and health

    OpenAIRE

    Martina eKöberl; Ruth eSchmidt; Elshahat M Ramadan; Rudolf eBauer; Gabriele eBerg

    2013-01-01

    Past medicinal plant research primarily focused on bioactive phytochemicals, however, the focus is currently shifting due to the recognition that a significant number of phytotherapeutic compounds are actually produced by associated microbes or through interaction with their host. Medicinal plants provide an enormous bioresource of potential use in modern medicine and agriculture, yet their microbiome is largely unknown. The objective of this review is (i) to introduce novel insights into the...

  12. People, plants and health: a conceptual framework for assessing changes in medicinal plant consumption

    Directory of Open Access Journals (Sweden)

    Smith-Hall Carsten

    2012-11-01

    Full Text Available Abstract Background A large number of people in both developing and developed countries rely on medicinal plant products to maintain their health or treat illnesses. Available evidence suggests that medicinal plant consumption will remain stable or increase in the short to medium term. Knowledge on what factors determine medicinal plant consumption is, however, scattered across many disciplines, impeding, for example, systematic consideration of plant-based traditional medicine in national health care systems. The aim of the paper is to develop a conceptual framework for understanding medicinal plant consumption dynamics. Consumption is employed in the economic sense: use of medicinal plants by consumers or in the production of other goods. Methods PubMed and Web of Knowledge (formerly Web of Science were searched using a set of medicinal plant key terms (folk/peasant/rural/traditional/ethno/indigenous/CAM/herbal/botanical/phytotherapy; each search terms was combined with terms related to medicinal plant consumption dynamics (medicinal plants/health care/preference/trade/treatment seeking behavior/domestication/sustainability/conservation/urban/migration/climate change/policy/production systems. To eliminate studies not directly focused on medicinal plant consumption, searches were limited by a number of terms (chemistry/clinical/in vitro/antibacterial/dose/molecular/trial/efficacy/antimicrobial/alkaloid/bioactive/inhibit/antibody/purification/antioxidant/DNA/rat/aqueous. A total of 1940 references were identified; manual screening for relevance reduced this to 645 relevant documents. As the conceptual framework emerged inductively, additional targeted literature searches were undertaken on specific factors and link, bringing the final number of references to 737. Results The paper first defines the four main groups of medicinal plant users (1. Hunter-gatherers, 2. Farmers and pastoralists, 3. Urban and peri-urban people, 4. Entrepreneurs and

  13. Use of traditional Chinese medicine in the management of urinary stone disease

    Directory of Open Access Journals (Sweden)

    Ricardo Miyaoka

    2009-08-01

    Full Text Available Objective: To assess the evidence-based literature supporting the use of traditional Chinese medicine Kampo herbal and Acupuncture in stone disease management. Materials and Methods: Four of the most commonly used herbal components of Kampo medicine in the treatment of stone disease are described according to their in vitro and in vivo effects. We also reviewed the role of Acupuncture in urologic clinical setting as well as its proposed mechanisms of action and results. Medline database was assessed using isolated and conjugated key words (Chinese Medicine, Kampo, Chinese Herbal, Calculi, Stone Disease, Kidney, Acupuncture, Herbal Medicine. Articles were reviewed and summarized. Results: Herbal medicine has been proven to be free from side-effects and therefore suitable for long term use therapy. Its antilithic beneficial effects include increased urinary volume, increased magnesium excretion (Takusya, inhibitory activity on calcium oxalate aggregation (Takusya, Wulingsan and Desmodyum styracyfolium, inhibition of calcium oxalate nucleation and hydroxyapatite internalization (Wulingsan. In contrast, acupuncture, has shown to be effective as a pre-treatment anxiolytic and analgesic during colic pain and extracorporeal shock wave lithotripsy treatment, reducing the need for complementary sedative drugs. Conclusion: Chinese traditional medicine is promising as regards its role in stone prevention. An effort must be made in order to standardize study protocols to better assess acupuncture results since each procedure differs in regards to selected acupoints, electrostimulation technique and adjunct anesthetics. Similarly, standardization of Kampo formulations and acceptable clinical endpoints (imaging vs. symptomatic events is needed.

  14. A cross-cultural study: anti-inflammatory activity of Australian and Chinese plants.

    Science.gov (United States)

    Li, Rachel W; Myers, Stephen P; Leach, David N; Lin, G David; Leach, Greg

    2003-03-01

    In this study, in vitro inhibitory effects of 33 ethanol extracts obtained from 24 plant species (representing 11 different families) on cyclooxygenase-1 (COX-1) were evaluated. The plant materials selected for this study have been used in aboriginal medicine in Australia and traditional medicine in China for the treatment of various diseases that are considered as inflammation in nature, e.g. asthma, arthritis, rheumatism, fever, edema, infections, snakebite and related inflammatory diseases. All of the selected plants, with one exception, showed inhibitory activity against COX-1, which supports their traditional uses. The most potent COX-1 inhibition were observed from the extracts of Acacia ancistrocarpa leaves (IC(50)=23 microg/ml). Ficus racemosa bark, Clematis pickeringii stem, Acacia adsurgens leaves, Tinospora smilacina stem and Morinda citrifolia fruit powder exhibited inhibition of COX-1 with the IC(50) of 100, 141, 144, 158 and 163 microg/ml, respectively. Aspirin and indomethacin used as the reference COX-1 inhibitors in this study inhibited COX-1 with IC(50) of 241 and 1.2 microg/ml, respectively. The findings of this study may explain at least in part why these plants have been traditionally used for the treatment of inflammatory conditions in Australian aboriginal medicine and traditional Chinese medicine. PMID:12576199

  15. ANTIMICROBIAL PROPERTIES OF ROOTS OF MEDICINAL PLANTS

    OpenAIRE

    S. Sini; N S Malathy

    2005-01-01

    Antibacterial properties of hexane, chloroform and aqueous extracts of roots of Acorus calamus, Aristolochia indica, Cyperus rotundus, Desmodium gangeticum, Holostemma ada– kodien and Kaempferia galanga, used in the traditional medicine were studied on Bacillus pumilis and Eschericia coli by disc diffusion method.

  16. Berberis lycium a Medicinal Plant with Immense Value

    Directory of Open Access Journals (Sweden)

    Monika Sood2

    2013-03-01

    Full Text Available Berberis lycium belong to family Berberidaceae is an evergreen shrub growing in Himalayan region. The various parts of the plant like root, bark, stem, leaves and fruits are used by the people as a medicine or food. This plant has also gained wide acceptance for its medicinal value in ayurvedic drugs. The plant is known to prevent liver disorders, abdominal disorders, skin diseases, cough, ophthalmic etc. Moreover the pharmacological studies have shown that plant is hypoglycemic, hyperlipidemic, hepatoprotective, anticarcinogenic and antipyretic properties. The fruits of the plant are also very nutritious and are rich source of vitamins, minerals, antioxidants, anthocyanin etc. These fruits are consumed in raw form or are utilized in the preparation of juices, jams, preserve etc. by the local inhabitants. In the present article an attempt has been made to summarize the various properties of Berberis lycium plant.

  17. Medicinal plants of the eastern region of Madagascar.

    Science.gov (United States)

    Novy, J W

    1997-01-01

    Sixty-eight plants used in the traditional medicinal practices of the Betsimisaraka and Tanala peoples of the eastern region of Madagascar are reported. Preparations and utilizations of these medicinal plants are as varied as the plants themselves. Some of the plants discussed are known to science, but because of the diversity of tribal groups in Madagascar, new preparations and utilizations of these plants were based on the ethnobotanical data collected from the Betsimisaraka and Tanala. Many of the plants discussed remain to be chemically tested. Ethnopharmacological information is in danger of being lost in Madagascar as slash and burn agriculture destroys much of the forest, and the elder traditional healers, often illiterate, pass away without handing down their knowledge. PMID:9032624

  18. Chinese medicine compound Changtong oral liquid on postoperative intestinal adhesions

    Institute of Scientific and Technical Information of China (English)

    Xi-Xiao Yang; Han-Ping Shi; Lian-Bing Hou

    2005-01-01

    AIM: The aim of this study was to observe the effect of a Chinese medicine compound Changtong oral liquid (CT) on tissue plasminogen activity (t-PA), plasminogen activator inhibitor (PAI), TGF-β1 and hydroxyproline (OHP).METHODS: Two sets of animal experiments were performed in the present study. Forty New Zealand rabbits and 48 Sprague-Dawley (SD) rats were assigned randomly to one of the five groups: sham adhesion, adhesion with saline, adhesion with low dosage of the CT, adhesion with middle dosage of the CT and adhesion with high dosage of the CT. t-PA and PAI activity in plasma, OHP and TGF-β1 expression in adhesion were investigated. Analysis of variance was used to test differences among groups.RESULTS: CT treatment increased plasma t-PA activity in rabbits but decreased TGF-β1 activity in rats. The data were expressed from low to high dose respectively as follows: t-PA, 46.1±8.6 μkat/L, 59.6±10.1 μkat/L, 64.0±11.5 μkat/L; TGF-β1 28±7.23%, 31±3.05%, 30±4.04%. There were significant differences compared with saline-treated animals (t-PA 26.4±5.1 μkat/L, TGF-β1 54±5.51%). OHP content in cecum of rabbits from middle and high but not low dose of CT lowered significantly as compared with saline-treated rabbits, 0.3641±0.1373, 0.3348±0.0321, 0.2757±0.0497 mg/g vs0.4183±0.0883 mg/g of protein, P>0.05, P<0.05, P<0.05 respectively. The rabbit plasma PAI activity and OHP content in abdominal wall had no difference in all groups.CONCLUSION: CT treatment significantly enhanced t-PA activity in rabbits, but decreased TGF-β1 content in rats, OHP content in cecum of rabbits, and failed to affect the activity of PAI and OHP content in abdominal wall in rabbits,compared with saline group. The result suggests that CT could effectively prevent adhesions without interfering wound healing.

  19. Promoting integrative medicine by computerization of traditional Chinese medicine for scientific research and clinical practice: The SuiteTCM Project

    Institute of Scientific and Technical Information of China (English)

    Arthur de Sá Ferreira

    2013-01-01

    BACKGROUND:Chinese and contemporary Western medical practices evolved on different cultures and historical contexts and,therefore,their medical knowledge represents this cultural divergence.Computerization of traditional Chinese medicine (TCM) is being used to promote the integrative medicine to manage,process and integrate the knowledge related to TCM anatomy,physiology,semiology,pathophysiology,and therapy.METHODS:We proposed the development of the SuiteTCM software,a collection of integrated computational models mainly derived from epidemiology and statistical sciences for computerization of Chinese medicine scientific research and clinical practice in all levels of prevention.The software includes components for data management (DataTCM),simulation of cases (SimTCM),analyses and validation of datasets (SciTCM),clinical examination and pattern differentiation (DiagTCM,Tongue TCM,and Pulse TCM),intervention selection (AcuTCM,HerbsTCM,and DietTCM),management of medical records (ProntTCM),epidemiologic investigation of sampled data (ResearchTCM),and medical education,training,and assessment (StudentTCM).DISCUSSION:The SuiteTCM project is expected to contribute to the ongoing development of integrative medicine and the applicability of TCM in worldwide scientific research and health care.The SuiteTCM 1.0 runs on Windows XP or later and is freely available for download as an executable application.

  20. Criminaliteit en traditionele Chinese medicijnen

    NARCIS (Netherlands)

    van Uhm, Daan

    2014-01-01

    Traditional Chinese medicine (TCM) is deeply rooted in the Chinese culture. Although thousands of animal and plant species are used for medicines legally, some medications contain more sinister elements; illegal animal or plant ingredients of protected species. What is the origin of this demand for

  1. Building Data Mart for Traditional Efficacy of Chinese Herbal Medicine%中药功效数据集市的研制

    Institute of Scientific and Technical Information of China (English)

    曹宜; 佘侃侃

    2012-01-01

    中药功效数据集市以中药功效数据为主题,采用维度建模方法,组织与功效相关的植物分类学信息、化学成分、中药药理信息,采集中药事实型数据和部分文献型数据,根据中药相关学科概念体系,划分维度层次,支持与中药功效相关的多途径、多层次检索,可为中药功效多维分析、数据挖掘和文本挖掘提供基础.%Data mart for traditional efficacy of Chinese herbal medicine is built around traditional efficacy,and dimensional modeling is adopted in this process. Plant taxonomy information, chemical constituents and pharmacological information are collected in the data mart, including the factual data and literature - based data of Chinese herbal medicine. Dimension hierarchy is divided according the concept of traditional Chinese medicine related system disciplines. Data mart for traditional efficacy of Chinese herbal medicine can be searched by multiple ways and levels, and used for multidimensional data analysis, data mining and text mining to reveal the essence of efficacy of Chinese herbs.

  2. Antioxidant Potential of Indigenous Medicinal Plants of District Gujrat Pakistan

    OpenAIRE

    Mohammad Rafiq Khan; Syed Ali Raza; Mohammad Arshad; Ayoub Rashid Ch; Abdul Razzaq

    2014-01-01

    The work reported in this article was carried out to explore hidden antioxidant potential of some medicinal plants of District Gujrat, Pakistan. Crude methanolic extracts of Cichorium intybus L, Malva sylvestris L, and Euphorbia milii L were initially screened by DPPH on TLC assay for their antioxidant activity. Diphenylpicrylhydrayl (DPPH) free radical scavenging activity was also determined for all plants. To assess the role of plants in lipid oxidation, PV of refined bleached and deodorize...

  3. Medicinal plants in an urban environment: the medicinal flora of Banares Hindu University, Varanasi, Uttar Pradesh

    Directory of Open Access Journals (Sweden)

    Bussmann Rainer W

    2007-11-01

    Full Text Available Abstract Varanasi is one of the oldest continuously inhabited cities of the world, and one of the most important Hindu pilgrimage sites. Despite this importance, very little information exits on the cities flora in general, and medicinal species found within its limit in particular. Traditional medicine plays a large role in Indian society. The presented study attempted to investigate if traditional plant use and availability of important common medicinal plants are maintained in urban environments. The paper presents information on the traditional uses of seventy-two plant species collected form the campus of Banares Hindu University, Varanasi, Uttar Pradesh, and highlights the uses of these plants by the local inhabitants.

  4. Genomics and Evolution in Traditional Medicinal Plants: Road to a Healthier Life

    OpenAIRE

    Da-Cheng Hao; Pei-Gen Xiao

    2015-01-01

    Medicinal plants have long been utilized in traditional medicine and ethnomedicine worldwide. This review presents a glimpse of the current status of and future trends in medicinal plant genomics, evolution, and phylogeny. These dynamic fields are at the intersection of phytochemistry and plant biology and are concerned with the evolution mechanisms and systematics of medicinal plant genomes, origin and evolution of the plant genotype and metabolic phenotype, interaction between medicinal pla...

  5. The cultivation of of medicinal and aromatique plants in Romania

    Directory of Open Access Journals (Sweden)

    Leon Sorin MUNTEAN

    1985-08-01

    Full Text Available Scientific research regarding medicinal plants started first in Cluj, where the Research Station for Medicinal Plants was first organized in Europe (1904. Research in this field was continued after 1930 by the staff of the Agronomy Researh Institute of Romania (ICAR. Beginning with 1975 the national research programme regarding the medicinal plants is coordinated by the Research Station for Medicinal and Aromatic Plants -SCPMA - Fundulea. Studies are performed in the experimental fields and in the laboratories of this institute and different other research stations and universities in Romania. Beginning with 1979, a new specialized periodical - Herba Romanica - published the main results in the field. At present there are cultivated in Romania about 60 different medicinal and aromatic plant species. Recently a tendency emerged toward the concentration of the production to the most suitable regions and the specialization of different farms for the cultivation of a more restricted number of species. In the second part of the paper the species studied and/or cultivated in the experimental fields of the Agronomy Institute Cluj-Napoca are presented with a chronological list of papers published by the stuff in the period 1975-1984.

  6. Determination of Properties of Selected Fresh and Processed Medicinal Plants

    Directory of Open Access Journals (Sweden)

    Shirley G. Cabrera

    2015-11-01

    Full Text Available The study aimed to determine the chemical properties, bioactive compounds, antioxidant activity and toxicity level of fresh and processed medicinal plants such as corn (Zea mays silk, pancitpancitan (Peperomiapellucida leaves, pandan (Pandanus amaryllifolius leaves, and commercially available tea. The toxicity level of the samples was measured using the Brine Shrimp Lethality Assay (BSLA. Statistical analysis was done using Statistical Package for Social Sciences (SPSS. Results showed that in terms of chemical properties there is significant difference between fresh and processed corn silk except in crude fiber content was noted. Based on proximate analyses of fresh and processed medicinal plants specifically in terms of % moisture, %crude protein and % total carbohydrates were also observed. In addition, there is also significant difference on bioactive compound contents such as total flavonoids and total phenolics between fresh and processed corn silk except in total vitamin E (TVE content. Pandan and pancit-pancitan showed significant difference in all bioactive compounds except in total antioxidant content (TAC. Fresh pancit-pancitan has the highest total phenolics content (TPC and TAC, while the fresh and processed corn silk has the lowest TAC and TVE content, respectively. Furthermore, results of BSLA for the three medicinal plants and commercially available tea extract showed after 24 hours exposure significant difference in toxicity level was observed. The percentage mortality increased with an increase in exposure time of the three medicinal plants and tea extract. The results of the study can served as baseline data for further processing and commercialization of these medicinal plants.

  7. Effect of Traditional Chinese Herbal Medicine with Antiquorum Sensing Activity on Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Weihua Chu

    2013-01-01

    Full Text Available Traditional Chinese herbal medicines (TCHMs were tested for their ability of antiquorum sensing. Water extracts of Rhubarb, Fructus gardeniae, and Andrographis paniculata show antiquorumsensing activity when using Chromobacterium violaceum CV12472 as reporter; the sub-MIC concentrations of these TCHMs were tested against AHL-dependent phenotypic expressions of PAO1. Results showed significant reduction in pyocyanin pigment, protease, elastase production, and biofilm formation in PAO1 without inhibiting the bacterial growth, revealing that the QSI by the extracts is not related to static or killing effects on the bacteria. The results indicate a potential modulation of bacterial cell-cell communication, P. aeruginosa biofilm, and virulence factors by traditional Chinese herbal medicine. This study introduces not only a new mode of action for traditional Chinese herbal medicines, but also a potential new therapeutic direction for the treatment of bacterial infections, which have QSI activity and might be important in reducing virulence and pathogenicity of pathogenic bacteria.

  8. Progress of Research in Treatment of Hyperlipidemia by Monomer or Compound Recipe of Chinese Herbal Medicine

    Institute of Scientific and Technical Information of China (English)

    DOU Xiao-bing; WO Xing-de; FAN Chun-lei

    2008-01-01

    Hyperlipidemia (HLP) is the No.1 risk factor for patients with atherosclerosis (AS) and is directly related to the occurrence of coronary artery disease (CAD) and cerebrovascular disease. Therefore, prevention and treatment of AS is of great importance and of practical significance in controlling the incidence and mortality of CAD. With its peculiar syndrome-dependent therapy, traditional Chinese medicine (TCM) has accumulated abundant practical experiences in this field and good clinical effects have been achieved. Chinese herbal medicine, with its particularly unique advantages and high potentials yet to be tapped, displays its huge strength in HLP prevention and treatment. The progress of studies concerning prevention and treatment of HLP by Chinese herbal medicines, in the form of monomers or compound recipes, is reviewed in this paper.

  9. The Impact of a Cultural Immersion Study Abroad Experience in Traditional Chinese Medicine.

    Science.gov (United States)

    Conroy, Shelley F; Taggart, Helen M

    2016-09-01

    Study abroad programs have increased dramatically. Most programs are short-term and include a cultural immersion as well as classroom and/or service learning. In this article, the authors discuss a study abroad program to China that included cultural immersion and classroom learning specific to traditional Chinese medicine. Participants kept journals with specific writing assignments and reflections about their experiences during the trip. At the conclusion of the trip, a qualitative survey was administered to the participants. Outcomes included the benefits of cultural immersion and a greater appreciation of cultural diversity, complementary and alternative medicine and holistic health care. Participants were able to describe transformational experiences of living in and learning from the Chinese culture and peoples. They intended to incorporate their experiences and enhanced understanding of traditional Chinese medicine and complementary and alternative therapies to provide culturally competent holistic health care in their nursing practice. PMID:26351293

  10. Mining Compatibility Rules from Irregular Chinese Traditional Medicine Database by Apriori Agorithm

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    This paper aims to mine the knowledge and rules on compatibility of drugs from the prescriptions for curing arrhythmia in the Chinese traditional medicine database by Apriori algorithm. For data preparation, 1 113 prescriptions for arrhythmia, including 535herbs (totally 10884 counts of herbs) were collected into the database. The prescription data were preprocessed through redundancy reduction, normalized storage, and knowledge induction according to the pretreatment demands of data mining. Then the Apriori algorithm was used to analyze the data and form the related technical rules and treatment procedures. The experimental result of compatibility of drugs for curing arrhythmia from the Chinese traditional medicine database shows that the prescription compatibility obtained by Apriori algorithm generally accords with the basic law of traditional Chinese medicine for arrhythmia. Some special compatibilities unreported were also discovered in the experiment, which may be used as the basis for developing new prescriptions for arrhythmia.

  11. Acupuncture plus Chinese Medicinal Fumigation and Washing for Edema of the Stroke-affected Limb

    Institute of Scientific and Technical Information of China (English)

    Wu Bin

    2014-01-01

    Objective: To evaluate the therapeutic efficacy of acupuncture plus Chinese medicinal fumigation and washing in treating edema of the affected limb in post-stroke hemiplegia. Methods: Two hundred patients with edema of the stroke-affected limb from our hospital were randomized into two groups according to their visiting sequence. In the observation group, 100 subjects were intervened by acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics, while the other 100 subjects in the control group were only given diuretics. The therapeutic efficacy was evaluated after successive 2-week treatments. Results: The total effective rate was 90.0% in the observation group, significantly higher than 66.0% in the control group, indicating that there was a significant difference in comparing the overall therapeutic effect (P Conclusion: Acupuncture plus Chinese medicinal fumigation and washing in addition to oral administration of diuretics is effective in treating edema of the affected limb in post-stroke hemiplegia.

  12. Roles of Chinese herbal medicines in ischemic heart diseases (IHD) by regulating oxidative stress.

    Science.gov (United States)

    Wang, Dawei; Wang, Jin; Liu, Yuntao; Zhao, Zhen; Liu, Qing

    2016-10-01

    Ischemic heart disease (IHD) basing on atherosclerosis (AS) is known as a top killer for decades. Oxidative stress, representing excessive oxidation and insufficient elimination, has been proved to be a critical molecular mechanism of IHD and accompanying myocardium dysfunction. Therefore, anti-oxidation therapy may be efficient. Chinese herbal medicine, including extractive compounds, decoctions, patent drugs, and injections, has shown its enormous potential in prevention and treatment of IHD as an effective antioxidant in experimental studies. The aim of this review is to highlight recent studies of Chinese herbal medicine in regulating oxidative stress in IHD. These studies represent recent progress of IHD treatment and indicate the possible pathways and target spots of Chinese herbal medicine. PMID:27390948

  13. [Application of ultrasound counter currentextraction in patent of traditional Chinese medicine].

    Science.gov (United States)

    Miao, Yan-ni; Wu, Bin; Yue, Xue-lian

    2015-07-01

    The patent information of ultrasound countercurrent extraction used in traditional Chinese medicine was analyzed in this paper by the samples from Derwent World Patent Database (DWPI) and the Chinese Patent Abstracts Database (CNABS). The application of ultrasound countercurrent was discussed with the patent applicant,the amount of the annual distribution, and the pharmaceutical raw materials and other aspects. While the technical parameters published in the patent was deeply analyzed, such as material crushing, extraction solvent, extraction time and temperature, extraction equipment and ultrasonic frequency. Thought above research, various technical parameters of ultrasound countercurrent extraction used in traditional Chinese was summarize. The analysis conclusion of the paper can be used in discovering the technical advantages, optimizing extraction conditions, and providing a reference to extraction technological innovation of traditional Chinese medicine.

  14. [Application of ultrasound counter currentextraction in patent of traditional Chinese medicine].

    Science.gov (United States)

    Miao, Yan-ni; Wu, Bin; Yue, Xue-lian

    2015-07-01

    The patent information of ultrasound countercurrent extraction used in traditional Chinese medicine was analyzed in this paper by the samples from Derwent World Patent Database (DWPI) and the Chinese Patent Abstracts Database (CNABS). The application of ultrasound countercurrent was discussed with the patent applicant,the amount of the annual distribution, and the pharmaceutical raw materials and other aspects. While the technical parameters published in the patent was deeply analyzed, such as material crushing, extraction solvent, extraction time and temperature, extraction equipment and ultrasonic frequency. Thought above research, various technical parameters of ultrasound countercurrent extraction used in traditional Chinese was summarize. The analysis conclusion of the paper can be used in discovering the technical advantages, optimizing extraction conditions, and providing a reference to extraction technological innovation of traditional Chinese medicine. PMID:26666026

  15. The research on traditional Chinese medicine anti-falling shampoo%中药防脱洗发水的研究

    Institute of Scientific and Technical Information of China (English)

    李秋芳; 龙致科; 胡永志; 周传检

    2016-01-01

    概述了中药的作用机理和中药植物防脱洗发水的研究进展。研究了桑叶、侧柏叶、曼荆子、川芎、桑白皮、茶麸六味植物成分在洗发水中的防脱效果,通过人体试验证明其具有较好的防脱发功效,中药液副作用小,不易引起皮肤过敏等皮肤问题;解决了高浓度中药植物提取液在洗发水中容易分层,难以稳定的技术问题。%The paper ummarizes the mechanism of traditional Chinese medicine and the research progress of Chinese medicine plant anti-failing shampoo. The raditional Chinese medicine effect of Mulberry leaf, Oriental arborvitae, mann chastetree fruit, rhizoma ligustici walichii, white mulberry root-bark, ChaFu which the shampoo includes has been studied . Through the human trials ,it has been proved that these six raditional Chinese medicine plants have effect on anti-failing hairs and these are not easy to cause skin problems such as skin alergy because of the less side effect ; It has been solved the technical problems that the high concentration of traditional Chinese medicine plant extracts in shampoo are easy to cause the layering phenom and the stability of the shampoo.

  16. Plant Molecular Farming: Much More than Medicines.

    Science.gov (United States)

    Tschofen, Marc; Knopp, Dietmar; Hood, Elizabeth; Stöger, Eva

    2016-06-12

    Plants have emerged as commercially relevant production systems for pharmaceutical and nonpharmaceutical products. Currently, the commercially available nonpharmaceutical products outnumber the medical products of plant molecular farming, reflecting the shorter development times and lower regulatory burden of the former. Nonpharmaceutical products benefit more from the low costs and greater scalability of plant production systems without incurring the high costs associated with downstream processing and purification of pharmaceuticals. In this review, we explore the areas where plant-based manufacturing can make the greatest impact, focusing on commercialized products such as antibodies, enzymes, and growth factors that are used as research-grade or diagnostic reagents, cosmetic ingredients, and biosensors or biocatalysts. An outlook is provided on high-volume, low-margin proteins such as industrial enzymes that can be applied as crude extracts or unprocessed plant tissues in the feed, biofuel, and papermaking industries. PMID:27049632

  17. Plant Molecular Farming: Much More than Medicines

    Science.gov (United States)

    Tschofen, Marc; Knopp, Dietmar; Hood, Elizabeth; Stöger, Eva

    2016-06-01

    Plants have emerged as commercially relevant production systems for pharmaceutical and nonpharmaceutical products. Currently, the commercially available nonpharmaceutical products outnumber the medical products of plant molecular farming, reflecting the shorter development times and lower regulatory burden of the former. Nonpharmaceutical products benefit more from the low costs and greater scalability of plant production systems without incurring the high costs associated with downstream processing and purification of pharmaceuticals. In this review, we explore the areas where plant-based manufacturing can make the greatest impact, focusing on commercialized products such as antibodies, enzymes, and growth factors that are used as research-grade or diagnostic reagents, cosmetic ingredients, and biosensors or biocatalysts. An outlook is provided on high-volume, low-margin proteins such as industrial enzymes that can be applied as crude extracts or unprocessed plant tissues in the feed, biofuel, and papermaking industries.

  18. A probe into the medicinal potential of Viola canescens – A threatened medicinal plant from Himalaya

    OpenAIRE

    Sidra Sabir; Abida Akram; Naveed Iqbal Raja; Zia-ur-Rehman Mashwani; Sohail; Huma Mehreen Sadaf; Mubashir Hussain; Iqra Riaz; Nabeela Ahmad; Ejaz Ahmed

    2016-01-01

    Viola canescens Wall. ex Roxb. is a perennial herb belonging to family Violaceae, and it is almost cosmopolitan in distribution. This plant is widely used in Ayurveda and Unani medicinal systems for curing various ailments, most commonly for cough and cold. Phytochemical studies releaved that this plant is rich in secondary metabolites. This plant revealed significant antimicrobial, anti-inflamatory, antioxidant, hepatoprotective, laxative, analgesic as well as antitumor activi...

  19. [A brief history of Chinese royal court medicines].

    Science.gov (United States)

    Li, Chun-Sheng

    2010-09-01

    With the establishment of an emperor and a royal court, the court physician came into being and the royal court medicines gradually began to evolve. In the first year of Kai Huang of the Sui dynasty (581), King Wendi of the Sui dynasty established the imperial medical bureau. Since then the royal court medicines entered a period of development and prosperity. In the Yuan dynasty, the scope of official duty of the imperial hospital narrowed, the development of royal court medicines lacked new growth. To the Ming and Qing dynasties, the royal court medicine began to decline and eventually ended with the demise of the Qing dynasty. PMID:21163077

  20. PHARMACOGNOSTIC AND PHARMACOLOGICAL PROFILE OF TRADITIONAL MEDICINAL PLANT: MYRICA NAGI

    OpenAIRE

    Ashok Kumar; A C Rana

    2012-01-01

    Myrica nagi belongs to myricaceae family. It is commonly known as Bay berry (English) and Kathphal (Hindi). Myrica nagi has a long history of usage in traditional medicine against various ailments. In Ayurvedic and other traditional medicinal practices the plant has been used against diseases like, fever, Cardiac debility, typhoid, diarrhoea, dysentery. Phytochemicals like glycosides, saponins tannins, flavonoids, triterpenes and sterols have been isolated. Important pharmacological activitie...

  1. Medicinal Plants In Traditional Use At Arunachal Pradesh, India

    Directory of Open Access Journals (Sweden)

    Nungki Perme

    2016-10-01

    Full Text Available In rural world, the use of medicinal plants in healthcare system is an integral source of easily available remedy. This study was conducted on herbal preparations of different plant parts used by the tribal people of Arunachal Pradesh for controlling the diseases. The villages like Yekar, Dulom, Sippi, Soki, lamdik in Upper Subansiri District, Ngopok, Passighat, in East Siang Distrivt, East Kameng District, West Kameng District, Lower Subansiri District of Arunachal Pradesh, India were surveyed through personal interviews with the villagers and medicine men and assistance of local information.  We recorded the traditional use of 101 medicinal plants species belonging to 50 taxonomic plant families used for treating a total of 156 different diseases/ailments. The informant consensus factor (ICF values demonstrated that local people tend to agree more with each other in terms of the plants used to treat malaria (0.71, jaundice (0.62, urological problems (0.56, dermatological disorders (0.45, pain (0.30, and respiratory disorder (0.33, and while the general health (0.15 and gastro-intestinal disorders category (0.28 were found low ICF values. The highest number of medicinal plants (101 species was reported from the Adi of Lower Dibang Valley followed by the Nocte of the Tirap (25 species and the Nyishi ethnic groups of Papum Pare districts (13 species.

  2. Antifungal activity of traditional medicinal plants from Tamil Nadu, India

    Institute of Scientific and Technical Information of China (English)

    Duraipandiyan V; Ignacimuthu S

    2011-01-01

    Objective:To assess the antifungal activity of hexane, ethyl acetate and methanol extracts of 45 medicinal plants and to determine the minimum inhibitory concentration for each extract against human pathogenic fungi. Methods:A total of 45 medicinal plants were collected from different places of Tamil Nadu and identified. Hexane, ethyl acetate and methanol extracts of 45 medicinal plants were assessed for antifungal susceptibility using broth microdilution method. Two known antifungal agents were used as positive controls. Results: Most of the extracts inhibited more than four fungal strains. From the evaluation we found that ethyl acetate extracts inhibited large number of fungal growth. Hexane extracts also nearly showed the same level of inhibition against fungal growth. Methanol extracts showed the minimum antifungal activity. Among the 45 plants tested, broad spectrum antifungal activity was detected in Albizzia procera (A. procera), Atalantia monophylla, Asclepias curassavica, Azima tetracantha, Cassia fistula (C. fistula), Cinnomomum verum, Costus speciosus (C. speciosus), Nymphaea stellata, Osbeckia chinensis, Piper argyrophyllum, Punica granatum, Tinospora cordifolia and Toddalia asiatica (T. asiatica). Promising antifungal activity was seen in A. procera, C. speciosus, C. fistula and T. asiatica. Conclusions:It can be concluded that the plant species assayed possess antifungal properties. Further phytochemical research is needed to identify the active principles responsible for the antifungal effects of some of these medicinal plants.

  3. Cameroonian medicinal plants: Pharmacology and derived natural products

    Directory of Open Access Journals (Sweden)

    Thomas Efferth

    2010-10-01

    Full Text Available Many developing countries including Cameroon have mortality patterns that reflect high levels of infectious diseases and the risk of death during pregnancy and childbirth, in addition to cancers, cardiovascular diseases and chronic respiratory diseases that account for most deaths in the developed world. Several medicinal plants are used traditionally for their treatment. In this review, plants used in Cameroonian traditional medicine with evidence for the activities of their crude extracts and/or derived products have been discussed. A considerable number of plant extracts and isolated compounds possess significant antimicrobial, antiparasitic including anti-malarial, anti-proliferative, anti-inflammatory, anti-diabetes, and antioxidant effects. Most of the biologically active compounds belong to terpenoids, phenolics and alkaloids. Terpenoids from Cameroonian plants showed best activities as anti-parasitic, but rather poor antimicrobial effects. The best antimicrobial, anti-proliferative and antioxidant compounds were phenolics. In conclusion, many medicinal plants traditionally used in Cameroon to treat various ailments displayed good activities in vitro. This explains the endeavor of Cameroonian research institutes in drug discovery from indigenous medicinal plants. However, much work is still to be done to standardize methodologies and to study the mechanisms of action of isolated natural products.

  4. Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs

    Institute of Scientific and Technical Information of China (English)

    Lin; Zhang; Anjaneya; S.Ravipati; Sundar; R; Koyyalamudi; Sang; Chul; Jeong; Narsimha; Reddy; John; Bartlett; Paul; T.Smith; Mercedes; de; la; Cruz; Maria; Cndida; Monteiro; ngeles; Melguizo; Ester; Jimnez; Francisca; Vicente

    2013-01-01

    Objective:To evaluate in ritro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential.Methods:A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use.The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi(Aspergillus funigaius),yeast(Candida albicans),gram-negative(Acirelobacter haumannii and Pseudornnruis aeruginosa)and gram-positive bacteria(Staphglococcus aureus).The activities were tested at three different concentrations of 1.00,0.10 and 0.01 mg/mL.The data was analysed using Gene data Screener program.Results:The measured antimicrobial activities indicated that out of the 58 plant extracts,15 extracts showed anti-fungal activity and 23 extracts exhibited anti-bacterial activity.Eight plant extracts have exhibited both anti-bacterial and anti-fungal activities.For instance,Eucommia ulmoides,Pohgonum cuspidcrtum,Poria cocas and Uncaria rhineophylla showed activity against both bacterial and fungal strains,indicating their broad spectrum of activity.Conclusions:The results revealed that the ethanol extracts of 30 plants out of the selected 58 possess significant antimicrobial activities.It is interesting to note that the findings from the current study are consistent with the traditional use.A clear correlation has also been found between the antimicrobial activity and the flavonoid content of the plant extracts which is in agreement with the literature.Hence.the results presented here can be used to guide the selection of potential plant species for the isolation and structure elucidation of novel antimicrobial compounds in order to establish the structure-activity relationship.This in turn is expected to lead the way to the discovery of novel antimicrobial agents for therapeutic use.

  5. Anti-fungal and anti-bacterial activities of ethanol extracts of selected traditional Chinese medicinal herbs

    Institute of Scientific and Technical Information of China (English)

    Lin Zhang; ngeles Melguizo; Ester Jimnez; Francisca Vicente; Anjaneya S Ravipati; Sundar R Koyyalamudi; Sang Chul Jeong; Narsimha Reddy; John Bartlett; Paul T Smith; Mercedes de la Cruz; Maria Cndida Monteiro

    2013-01-01

    Objective:To evaluate in vitro antimicrobial activities of selected 58 ethno-medicinal plant extracts with a view to assess their therapeutic potential. Methods:A total of 58 traditional Chinese medicinal plants were carefully selected based on the literature review and their traditional use. The antimicrobial activities of ethanol extracts of these medicinal plants were tested against fungi (Aspergillus fumigatus), yeast (Candida albicans), gram-negative (Acinetobacter baumannii and Pseudomonas aeruginosa) and gram-positive bacteria (Staphylococcus aureus). The activities were tested at three different concentrations of 1.00, 0.10 and 0.01 mg/mL. The data was analysed using Gene data Screener program. Results: The measured antimicrobial activities indicated that out of the 58 plant extracts, 15 extracts showed anti-fungal activity and 23 extracts exhibited anti-bacterial activity. Eight plant extracts have exhibited both anti-bacterial and anti-fungal activities. For instance, Eucommia ulmoides, Polygonum cuspidatum, Poria cocos and Uncaria rhyncophylla showed activity against both bacterial and fungal strains, indicating their broad spectrum of activity. Conclusions: The results revealed that the ethanol extracts of 30 plants out of the selected 58 possess significant antimicrobial activities. It is interesting to note that the findings from the current study are consistent with the traditional use. A clear correlation has also been found between the antimicrobial activity and the flavonoid content of the plant extracts which is in agreement with the literature. Hence, the results presented here can be used to guide the selection of potential plant species for the isolation and structure elucidation of novel antimicrobial compounds in order to establish the structure-activity relationship. This in turn is expected to lead the way to the discovery of novel antimicrobial agents for therapeutic use.

  6. Some medicinal plants with aphrodisiac potential:A current status

    Institute of Scientific and Technical Information of China (English)

    Ramandeep Singh; Ashraf Ali; Gaurav Gupta; Alok Semwal; G Jeyabalan

    2013-01-01

    Aphrodisiac is the word derived fromAphrodite, theGreek goddess of sexual, love and beauty. An aphrodisiac is defined as an agent(food or drug) that arouses sexual desire.Current sexual dysfunction therapy lack satisfactory success due to adverse effect, hence patients are seeking complementary and alternative medicine to treat sexual dysfunction.Ayurveda and otherIndian literature mention the use of plants in various human ailments.India has about more than45000 plant species and among them several thousand are claimed to possess medicinal properties. Researchers conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for sexual dysfunction.This review reveals that some plants and their extract have aphrodisiac activity, which are helpful for researcher to develop new herbal aphrodisiac formulations.In the recent years, interest in drugs of plant origin has been progressively increased.

  7. Some medicinal plants with aphrodisiac potential: A current status

    Directory of Open Access Journals (Sweden)

    Ramandeep Singh

    2013-01-01

    Full Text Available Aphrodisiac is the word derived from Aphrodite, the Greek goddess of sexual, love and beauty. An aphrodisiac is defined as an agent (food or drug that arouses sexual desire. Current sexual dysfunction therapy lack satisfactory success due to adverse effect, hence patients are seeking complementary and alternative medicine to treat sexual dysfunction. Ayurveda and other Indian literature mention the use of plants in various human ailments. India has about more than 45 000 plant species and among them several thousand are claimed to possess medicinal properties. Researchers conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for sexual dysfunction. This review reveals that some plants and their extract have aphrodisiac activity, which are helpful for researcher to develop new herbal aphrodisiac formulations. In the recent years, interest in drugs of plant origin has been progressively increased.

  8. [Controllability pyramid: an integrated control system of quality for traditional Chinese medicines].

    Science.gov (United States)

    Xiao, Xiao-He; Zhang, Ding-Kun; Wang, Jia-Bo; Yang, Ming; Peng, Cheng

    2015-01-01

    Quality control is one of the key scientific tissues in the modernization of traditional Chinese medicines (TCM). In order to overcome the deficiencies of assessment indexes, including little systematization and quantification, as well as loose association with clinical efficacy and dosage, a new integrated method named controllability pyramid ( CP) is first proposed in this paper. In addition, some study cases are used to explain how this model is constructed. We hope the establishment of CP could promote the clinical-orien- ted integrated innovation research of TCM, and provide control strategy and technology examples for improving the quality of Chinese medicines and clinical efficacy.

  9. Clinical Study on Treatment of Hyperuricaemia by Retention Enema of Chinese Herbal Medicine Combined with Allopurinol

    Institute of Scientific and Technical Information of China (English)

    陈茜; 马丽; 阿克拜尔·乌普

    2009-01-01

    Objective:To study the effect of retention enema of Chinese herbal medicine combined with allopurinol in treating hyperuricaemia(HUE).Methods:Seventy-eight patients with HUE were assigned to two groups,the 40 patients in the treated group were treated with retention enema of Chinese herbal medicine combined with oral intake of allopurinol,and the 38 patients in the control group were treated with allopurinol alone. The therapeutic course for all was 6 weeks.The clinical efficacy,changes of symptoms,blood...

  10. [Changes of career of traditional Chinese medicine in Hong Kong Donghua Hospital in modern times].

    Science.gov (United States)

    Zheng, H

    2016-05-01

    Founded in 1872, the Hong Kong Donghua Hospital (Tung Wah Group of Hospitals later) was the earliest traditional Chinese hospital in modern times, which has made positive contributions in exploring the shape and structure of TCM hospital and promoting science of TCM in Hong Kong. Unfortunately, TCM didn't acquire a legal status in Hong Kong, the practice of TCM in Donghua Hospital was thus restricted by the government, and ultimately, it changed into a comprehensive hospital mainly use western medicine. The change of TCM business in Hong Kong Donghua Hospital reflected the problems and situation of traditional Chinese medicine encountered in modern times. PMID:27485869

  11. Application of Systems Biology Technology in Research of Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    LI Ping; YANG Li-ping; GONG Yue-wen

    2009-01-01

    Systems biology is an emerging science of the 21 st century and its method and design of study resemble those of traditional Chinese medicine (TCM). Adopting systems biology technology will help to understand TCM Syndromes and modernize Chinese herbal medicine. The technology platforms of systems biology,especially proteomics can provide useful tools for exploring essence of TCM syndromes and understanding principle of herbal formulation. Moreover, compared with methods of molecular biology, such as genomics and proteomics, metabolomics provide more direct, rapid, concise and effective methods for study of kidney disease especiallv in the case of prevention and treatment with TCM.

  12. Research advances on the anti-aging profile of Fructus lycii: An ancient Chinese herbal medicine

    OpenAIRE

    Sze, SCW; Chang, RCC; Zhang, KY; Tong, Y; Song, J.; Wong, RNS

    2008-01-01

    Fructus lycii is a common Chinese herbal medicine used in China for nearly 2000 years. It has beneficial effects on eyes, liver and kidneys; and it has long been considered to be an anti-aging herb in ancient Chinese medicine. Modern studies have partially probed the magic anti-aging property of F. lycii. The beneficial effects of F. lycii on aging are largely attributed to its bioactive components such as polysaccharides, carotenoids and flavonoids. This review focuses on the anti-aging aspe...

  13. Several considerations in using traditional Chinese patent medicine for cerebral infarction.

    Science.gov (United States)

    He, Jia; Kwon, Yihyun; Li, Chao; Zhang, Xue-Qi; Zhao, Jian-Guo

    2012-08-01

    Nowadays, a great number of traditional Chinese patent medicine (TCPM) are used more and more widely to treat cerebral infarction in China. When great attention is paid to using TCPM in the real world, several problems can be identified: ignoring the Chinese medicine (CM) therapeutic principle based on syndrome differentiation, a lack of appropriate dosage and usage based on individual patient conditions, and a shortage of evidence from randomized, double-blind, placebo-controlled clinical trials. Furthermore, in terms of evaluation of the TCPM effectiveness, few comprehensive criteria and evaluation methods recognized by the international community exist. This article addresses some opinions regarding the above mentioned problems. PMID:22855032

  14. [Strategy and core technologies for the secondary development of Chinese patent medicine].

    Science.gov (United States)

    Zhagn, Bo-Li; Fan, Xiao-Hui; Liu, Yang; Qu, Hai-Bin; Zhang, Jun-Hua; Chegn, Yi-Yu

    2013-11-01

    Secondary development of Chinese Patent Medicine (CPM) is an effective and innovation-driven way for the leaping development of Chinese medicine industry with less investment and faster return. Aim to improving the efficacy, safety and batch-to-batch consistency of CPMs, the theory and methodology for the secondary development of CPMs, mode for cultivating superior CPM, approaches to reforming the pharmaceutical technology and the corresponding core technologies were proposed in this paper, which is summarized as 'One objective, Three analyses, Five definitudes and Seven improvements'. PMID:24558853

  15. POTENTIAL OF MEDICINAL PLANTS IN KIDNEY, GALL AND URINARY STONES

    Directory of Open Access Journals (Sweden)

    Choubey Ankur

    2010-06-01

    Full Text Available Medicinal plants have been known for millennia and are highly esteemed all over the world as a rich source of therapeutic agents for the prevention of various ailments. Today large number of population suffers from kidney stone, gall stone and urinary calculi. Stone disease has gained increasing significance due to changes in living conditions i.e. industrialization and malnutrition. Changes in prevalence and incidence, the occurrence of stone types and stone location, and the manner of stone removal are explained. Medicinal plants are used from centuries due to its safety, efficacy, cultural acceptability and lesser side effects as compared to synthetic drugs. The present article deals with measures to be adopted for the potential of medicinal plants in stone dissolving activity.

  16. Antibacterial activity of five Peruvian medicinal plants against Pseudomonas aeruginosa

    Institute of Scientific and Technical Information of China (English)

    Gabriela; Ulloa-Urizar; Miguel; Angel; Aguilar-Luis; María; del; Carmen; De; Lama-Odría; José; Camarena-Lizarzaburu; Juana; del; Valle; Mendoza

    2015-01-01

    Objective: To evaluate the susceptibility of Pseudomonas aeruginosa(P. aeruginosa)in vitro to the ethanolic extracts obtained from five different Peruvian medicinal plants.Methods: The plants were chopped and soaked in absolute ethanol(1:2, w/v). The antibacterial activity of compounds against P. aeruginosa was evaluated using the cupplate agar diffusion method.Results: The extracts from Maytenus macrocarpa("Chuchuhuasi"), Dracontium loretense Krause("Jergon Sacha"), Tabebuia impetiginosa("Tahuari"), Eucalyptus camaldulensis Dehn(eucalyptus), Uncaria tomentosa("U?a de gato") exhibited favorable antibacterial activity against P. aeruginosa. The inhibitory effect of the extracts on the strains of P. aeruginosa tested demonstrated that Tabebuia impetiginosa and Maytenus macrocarpa possess higher antibacterial activity.Conclusions: The results of the present study scientifically validate the inhibitory capacity of the five medicinal plants attributed by their common use in folk medicine and contribute towards the development of new treatment options based on natural products.

  17. Antibacterial activity of ifve Peruvian medicinal plants against Pseudomonas aeruginosa

    Institute of Scientific and Technical Information of China (English)

    Gabriela Ulloa-Urizar; Miguel Angel Aguilar-Luis; Mara del Carmen De Lama-Odra; Jos Camarena-Lizarzaburu; Juana del Valle Mendoza

    2015-01-01

    Objective:To evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) in vitro to the ethanolic extracts obtained from five different Peruvian medicinal plants. Methods:The plants were chopped and soaked in absolute ethanol (1:2, w/v). The antibacterial activity of compounds against P. aeruginosa was evaluated using the cup-plate agar diffusion method. Results:The extracts from Maytenus macrocarpa (“Chuchuhuasi”), Dracontium loretense Krause (“Jergon Sacha”), Tabebuia impetiginosa (“Tahuari”), Eucalyptus camaldulensis Dehn (eucalyptus), Uncaria tomentosa (“Uña de gato”) exhibited favorable antibacterial activity against P. aeruginosa. The inhibitory effect of the extracts on the strains of P. aeruginosa tested demonstrated that Tabebuia impetiginosa and Maytenus macrocarpa possess higher antibacterial activity. Conclusions:The results of the present study scientifically validate the inhibitory capacity of the five medicinal plants attributed by their common use in folk medicine and contribute towards the development of new treatment options based on natural products.

  18. In vitro screening of traditionally used medicinal plants in China against Enteroviruses

    Institute of Scientific and Technical Information of China (English)

    Jin-Peng Guo; Ji Pang; Xin-Wei Wang; Zhi-Qiang Shen; Min Jin; Jun-Wen Li

    2006-01-01

    AIM: To search for new antiviral agents from traditional Chinese medicine, specifically anti-enterovirosuses agents.METHODS: The aqueous extracts (AE) of more than 100 traditionally used medicinal plants in China were evaluated for their in vitro anti-Coxsackie virus B3 activities with a NTT-based colorimetric assay.RESULTS: The test for AE of 16 plants exhibited antiCoxsackie virus B3 activities at different magnitudes of potency. They can inhibit three steps (inactivation,adsorption and replication) during the infection. Among the 16 plants, Sargentodoxa cuneata (Oliv.) Rehd. et Wils., Sophora tonkinensis Gapnep., Paeonia veitchii Lynch, Spatholobus suberectus Dunn. and Cyrtomium fortunei J. sm. also have activity against other enterovirus, including Coxsackie virus B5, Polio virus I, Echo virus 9 and Echo virus 29. Cell cytotoxic assay demonstrated that all tested AE had CC 50 values higher than their EC50 values.CONCLUSION: The sixteen traditionally used medicinal plants in China possessed antiviral activity, and some of them merit further investigations.

  19. Current status of Indian medicinal plants with aphrodisiac potential

    Institute of Scientific and Technical Information of China (English)

    Ramandeep Singh; Ashraf Ali; G Jeyabalan; Alok Semwal

    2013-01-01

    In India, indigenous remedies have been used in treatment of sexual dysfunction since the time of Charaka and Sushruta. Plants have been always an exemplary source of drugs and many of the currently available drugs have been derived directly or indirectly from them. An aphrodisiac is defined as an agent that arouses sexual desire. Erectile dysfunction or sexual dysfunction (ED or SD) or male impotence is defined as the inability of a man to achieve and maintain an erection sufficient for mutually satisfactory intercourse with his partner. Sexual health and function are important determinants of quality of life. To overcome the problem of male sexual (or) erectile dysfunction, various Indian natural aphrodisiac plants potentials were preferred. The ethnobotanical information reports that about 200 plants possess aphrodisiac potential. Out of several Indian medicinal plants, 33 plants were reviewed. In this review, studies on Indian medicinal plants were reviewed and their possible therapeutic applications were discussed. This review discusses about aphrodisiac potential of Indian medicinal plants, its botanical name, common name, family, extract, models used, part used and references, which are helpful for researchers to develop new herbal aphrodisiac formulations. In the recent years, interest in drugs of plant origin has been progressively increased.

  20. Treatment of 140 cerebral palsied children with a combined method based on traditional Chinese medicine (TCM) and western medicine

    Institute of Scientific and Technical Information of China (English)

    ZHOU Xue-juan; ZHENG Kun

    2005-01-01

    Objective: To observe and evaluate a method that is effective and practical for treatment of cerebral palsied (CP)children in China. Method: The patient's age and disease type and individual specific conditions were considered in choosing therapy methods accordingly: Chinese herbs, acupuncture, auricular seed pressure, point finger pressing, massage, orthopedic hand manipulation, physiotherapy, occupational therapy, language therapy, etc. Meanwhile we created a new CP treatment model that combines hospitalized treatment with family therapy. Results: The majority of CP patients improved greatly in motor and social adaptation capacities after treatment. Wilcoxon paired rank sum test analysis showed that there were significant differences between the data before and after treatment (P<0.01). Conclusion: This combined therapy method, based on traditional Chinese medicine and western medicine plus family supplemental therapy, is an effective and practical treatment strategy for CP children in China.

  1. Synergistic effects of Chinese herbal medicine: a comprehensive review of methodology and current research

    Directory of Open Access Journals (Sweden)

    Xian Zhou

    2016-07-01

    Full Text Available Traditional Chinese medicine is an important part of primary health care in Asian countries that has utilised complex herbal formulations (consisting 2 or more medicinal herbs for treating diseases over thousands of years. There seems to be a general assumption that the synergistic therapeutic effects of Chinese herbal medicine derive from the complex interactions between the multiple bioactive components within the herbs and/or herbal formulations. However, evidence to support these synergistic effects remains weak and controversial due to several reasons, including the very complex nature of Chinese herbal medicine, misconceptions about synergy, methodological challenges to study design. In this review, we clarify the definition of synergy, identify common errors in synergy research and describe current methodological approaches to test for synergistic interaction. We discuss the strengthen and weakness of these models in the context of Chinese herbal medicine and summarise the current status of synergy research in CHM. Despite the availability of some scientific data to support the synergistic effects of multi-herbal and/or herb-drug combinations, the level of evidence remains low and the clinical relevancy of most of these findings is undetermined. There remain significant challenges in the development of suitable methods for synergistic studies of complex herbal combinations.

  2. Current Status and Future Perspective in the Globalization of Traditional Chinese Medicines

    Directory of Open Access Journals (Sweden)

    Wan-Ying Wu

    2015-01-01

    Full Text Available Globalization of traditional Chinese medicines started around 1996, which was initiated by the Chinese government. However, substantial progress was only achieved in recent years including the adoption of TCM quality monographs in the western pharmacopoeias (United States Pharmacopoeia and European Pharmacopoeia and registration in main stream drug regulatory agencies such as US Food and Drug Administration (FDA and European Medicines Agency (EMA. So far, several TCM herbal quality monographs were adopted by the United States Pharmacopoeia including Chinese Salvia, Ganoderma lucidum and Panax notoginseng, etc. Over 45 TCM quality monographs were recorded in the European Pharmacopoeia with 20 more in progress. After the successful registration of the first TCM product named Diao Xin Xue Kang as traditional medicine via the Medicines Evaluation Board of the Netherlands, several other TCM herbal products are in the registration process in several European member states. So far, there has been still not any TCM product authorized as a drug by the FDA regardless of a few TCM products in phase III or phase II clinical trials. This review summarizes the progress made in the globalization of traditional Chinese medicines in recent years and future issues in this regard.

  3. Phytochemical importance of medicinal plants as potential sources of anticancer agents

    OpenAIRE

    RAINA, Himani; Soni, Garima; JAUHARI, Nupur; Sharma, Neelam; BHARADVAJA, Navneeta

    2014-01-01

    The diverse and magnificent plant kingdom of the world is widely known for its medicinal importance. The potential medicinal properties of plant species have contributed significantly in the development of various herbal therapies for a number of diseases across the globe. The benefits of herbal medicine over allopathic medicine have helped medicinal plants to regain their importance in the field of health and medicine. Cancer is one of the major health problems that have widely affected the ...

  4. Review on medicinal uses, pharmacological, phytochemistry and immunomodulatory activity of plants.

    Science.gov (United States)

    Akram, M; Hamid, A; Khalil, A; Ghaffar, A; Tayyaba, N; Saeed, A; Ali, M; Naveed, A

    2014-01-01

    Since ancient times, plants have been an exemplary source of medicine. Researchers have discovered some important compounds from plants. The present work constitutes a review of the medicinal plants whose immunomodulant activity has been proven. We performed PUBMED, EMBASE, Google scholar searches for research papers of medicinal plants having immunomodulant activity. Medicinal plants used by traditional physicians or reported as having immunomodulant activity include Acacia concocinna, Camellia sinensis, Lawsonia inermis Linn, Piper longum Linn, Gelidium amansii, Petroselinum crispum, Plantago major and Allium sativum. Immunomodulant activities of some of these medicinal plants have been investigated. The medicinal plants documented have immunomodulant activity and should be further investigated via clinical trial. PMID:25280022

  5. Herbal traditional Chinese medicine and its evidence base in gastrointestinal disorders

    OpenAIRE

    Teschke, Rolf; Wolff, Albrecht; Frenzel, Christian; Eickhoff, Axel; Schulze, Johannes

    2015-01-01

    Herbal traditional Chinese medicine (TCM) is used to treat several ailments, but its efficiency is poorly documented and hence debated, as opposed to modern medicine commonly providing effective therapies. The aim of this review article is to present a practical reference guide on the role of herbal TCM in managing gastrointestinal disorders, supported by systematic reviews and evidence based trials. A literature search using herbal TCM combined with terms for gastrointestinal disorders in Pu...

  6. Qualitative and Quantitative Analysis for Facial Complexion in Traditional Chinese Medicine

    OpenAIRE

    Changbo Zhao; Guo-zheng Li; Fufeng Li; Zhi Wang; Chang Liu

    2014-01-01

    Facial diagnosis is an important and very intuitive diagnostic method in Traditional Chinese Medicine (TCM). However, due to its qualitative and experience-based subjective property, traditional facial diagnosis has a certain limitation in clinical medicine. The computerized inspection method provides classification models to recognize facial complexion (including color and gloss). However, the previous works only study the classification problems of facial complexion, which is considered as ...

  7. Review on the course of Chinese medicine regulation in the UK of the last 10 years.

    OpenAIRE

    Cheng, Ming Zhao; Shen, Huijun

    2010-01-01

    This article reviews the course of work in the last ten years of developing a system of statutory regulation of practitioners of acupuncture, herbal medicine and Traditional Chinese Medicine. It tracks from the House of Lords Science Select Committee report on complementary medcine in 2000 till the recent 2nd Department of Health's consultation on the regulation of these professionals. It would be very interesting to see what decision of the DH is to make on regualtion of these pratitioners.

  8. Features and distribution patterns of Chinese endemic seed plant species

    Institute of Scientific and Technical Information of China (English)

    Ji-Hong HUANG; Jian-Hua CHEN; Jun-Sheng YING; Ke-Ping MA

    2011-01-01

    We compiled and identified a list of Chinese. endemic seed plant species based on a large number of published References and expert reviews. The characters of these seed plant species and their distribution patterns were described at length. China is rich in endemic seed plants, with a total of 14 939 species (accounting for 52.1%of its total seed plant species) belonging to 1584 genera and 191 families. Temperate families and genera have a significantly higher proportion of endemism than cosmopolitan and tropical ones. The most primitive and derived groups have significantly higher endemism than the other groups. The endemism of tree, shrub, and liana or vine is higher than that of total species; in contrast, the endemism of herb is lower than that of total species. Geographically,these Chinese endemic plants are mainly distributed in Yunnan and Sichuan provinces, southwest China. Species richness and proportion of these endemic plants decrease with increased latitude and have a unimodal response to altitude. The peak value of proportion of endemism is at higher altitudes than that of total species and endemic species richness. The proportions of endemic shrub, liana or vine, and herb increase with altitude and have a clear unimodal curve. In contrast, the proportion of tree increases with altitude, with a sudden increase at~4000 m and has a completely different model. To date, our study provides the most comprehensive list of Chinese endemic seed plant species and their basic composition and distribution features.

  9. Ethnomedicinal Evaluation of Medicinal Plants Used against Gastrointestinal Complaints

    Directory of Open Access Journals (Sweden)

    Akash Tariq

    2015-01-01

    Full Text Available Aim of the present study was to document ethnomedicinal plants used against gastrointestinal complaints in five selected remote regions of Pakistan and to select potential medicinal plants for further in vitro and in vivo investigation. Data on ethnomedicinal plants and ethnographic profile of respondents was documented using semistructured questionnaires. The present study revealed utilization of 52 medicinal plants for the treatment of different gastrointestinal infections in studied regions. Apiaceae was the most dominant family reported to be used for the treatment of these infections (4 plants. Among all the plant parts fruit (24%, whole plants and leaves (23% each were the most preferred plant parts used by the healers. Dosage of recipe was found to be related with the age of the patient. Highest degree of informant consensus was reported for vomiting, nausea (0.92 each, abdominal pain (0.9, and diarrhea (0.89. Withania coagulans scored highest FL value (86% followed by Mentha longifolia and Melia azadirachta ranked second with FL value (75% each. Young generation was found to possess little traditional knowledge about utilizing plant recipes against these infections. Plants with high Fic and FL values should be subjected for further phytochemical and pharmacological investigation for scientific validation.

  10. Rice-Traditional Medicinal Plant in India

    Directory of Open Access Journals (Sweden)

    M. Umadevi

    2012-05-01

    Full Text Available Rice is rich in genetic diversity, with thousands of varieties grown throughout the world. Rice cultivation is the principal activity and source of income for about 100 million households in Asia and Africa. Rice has potential in a wide range of food categories. Besides having nutritional and medicinal benefits, the by-products of rice are equally important and beneficial. By-products from growing rice create many valuable and worthwhile products. The unedible parts, that are discarded through the milling process, and the edible part could be transformed into some of the following suggested products. Rice can be used to treat skin conditions. The rice is boiled, drained and allowed to cool and mashed. The rice is made into a paste or moulded into balls and these can be applied to boils, sores, swellings and skin blemishes. Other herbs are sometimes added to the rice balls to increase their medicinal effects. Sticky glutinous rice is often taken to treat stomach upsets, heart-burn and indigestion. Extracts from brown rice have been used to treat breast and stomach cancer and warts. They have also been used to treat indigestion, nausea and diarrhoea.

  11. Medicinal Plants for the Treatment of Hypertrophic Scars

    Directory of Open Access Journals (Sweden)

    Qi Ye

    2015-01-01

    Full Text Available Hypertrophic scar is a complication of wound healing and has a high recurrence rate which can lead to significant abnormity in aesthetics and functions. To date, no ideal treatment method has been established. Meanwhile, the underlying mechanism of hypertrophic scarring has not been clearly defined. Although a large amount of scientific research has been reported on the use of medicinal plants as a natural source of treatment for hypertrophic scarring, it is currently scattered across a wide range of publications. Therefore, a systematic summary and knowledge for future prospects are necessary to facilitate further medicinal plant research for their potential use as antihypertrophic scar agents. A bibliographic investigation was accomplished by focusing on medicinal plants which have been scientifically tested in vitro and/or in vivo and proved as potential agents for the treatment of hypertrophic scars. Although the chemical components and mechanisms of action of medicinal plants with antihypertrophic scarring potential have been investigated, many others remain unknown. More investigations and clinical trials are necessary to make use of these medical plants reasonably and phytotherapy is a promising therapeutic approach against hypertrophic scars.

  12. Chinese Herbal Medicine in Folk Custom%民俗中的中草药略识

    Institute of Scientific and Technical Information of China (English)

    齐敏; 李春芳

    2009-01-01

    There are large amount of Chinese herbal medicine used in folk custom of our country. Most of these medicines are related with hygiene and health care. The usage of these medicine included avoiding dirty, preventing diseases, restoring convalescence, health protection, cosmetology, bathing, and daily effective medical prescription. Folk custom has the characteristics of regionality, consistency, and nationality,ete. Some of traditional Chinese medicine originates from folk custom. Therefore, the research of medicine used in folk custom may help to the development of traditional Chinese medicine.%在我国传统民俗中流传有大量中草药,其用途主要包括辟秽防病、康复保健、美容化妆、服饰佩物、洗浴、日常疗病等.民俗为群体性、倾向性的社会行为,并有地域性、传承性、历史性、民族性等特点,同时中草药中的一部分药物也来源于民俗,研究民俗中的药物可有助于研发中药新药.

  13. Medicinal plants of India with anti-diabetic potential.

    Science.gov (United States)

    Grover, J K; Yadav, S; Vats, V

    2002-06-01

    Since ancient times, plants have been an exemplary source of medicine. Ayurveda and other Indian literature mention the use of plants in treatment of various human ailments. India has about 45000 plant species and among them, several thousands have been claimed to possess medicinal properties. Research conducted in last few decades on plants mentioned in ancient literature or used traditionally for diabetes have shown anti-diabetic property. The present paper reviews 45 such plants and their products (active, natural principles and crude extracts) that have been mentioned/used in the Indian traditional system of medicine and have shown experimental or clinical anti-diabetic activity. Indian plants which are most effective and the most commonly studied in relation to diabetes and their complications are: Allium cepa, Allium sativum, Aloe vera, Cajanus cajan, Coccinia indica, Caesalpinia bonducella, Ficus bengalenesis, Gymnema sylvestre, Momordica charantia, Ocimum sanctum, Pterocarpus marsupium, Swertia chirayita, Syzigium cumini, Tinospora cordifolia and Trigonella foenum graecum. Among these we have evaluated M. charantia, Eugenia jambolana, Mucuna pruriens, T. cordifolia, T. foenum graecum, O. sanctum, P. marsupium, Murraya koeingii and Brassica juncea. All plants have shown varying degree of hypoglycemic and anti-hyperglycemic activity. PMID:12020931

  14. Antibacterial activity of selected Myanmar medicinal plants

    International Nuclear Information System (INIS)

    Thirteen plants which are traditionally used for the treatment of dysentery and diarrhoea in Myanmar were selected and tested for antibacterial activity by using agar disc diffusion technique. Polar and nonpolar solvents were employed for extraction of plants. The minimum inhibitory concentration (MIC) of the extracts with the most significant predominant activity were evaluated by plate dilution method. The plants Eugenia jambolana, Quisqualis indica, Leucaena glauca and Euphorbia splendens var. 1 were found to show significant antibacterial activity. It was also observed that extracts using nonpolar solvents did not show any antibacterial activity and extracts using polar solvents showed antibacterial activity on tested bacteria, indicating that the active chemical compound responsible for the antibacterial action must be a polar soluble compound. (author)

  15. [Method of traditional Chinese medicine formula design based on 3D-database pharmacophore search and patent retrieval].

    Science.gov (United States)

    He, Yu-su; Sun, Zhi-yi; Zhang, Yan-ling

    2014-11-01

    By using the pharmacophore model of mineralocorticoid receptor antagonists as a starting point, the experiment stud- ies the method of traditional Chinese medicine formula design for anti-hypertensive. Pharmacophore models were generated by 3D-QSAR pharmacophore (Hypogen) program of the DS3.5, based on the training set composed of 33 mineralocorticoid receptor antagonists. The best pharmacophore model consisted of two Hydrogen-bond acceptors, three Hydrophobic and four excluded volumes. Its correlation coefficient of training set and test set, N, and CAI value were 0.9534, 0.6748, 2.878, and 1.119. According to the database screening, 1700 active compounds from 86 source plant were obtained. Because of lacking of available anti-hypertensive medi cation strategy in traditional theory, this article takes advantage of patent retrieval in world traditional medicine patent database, in order to design drug formula. Finally, two formulae was obtained for antihypertensive. PMID:25850277

  16. Prospects and Challenges for Harnessing Opportunities in Medicinal Plants Sector in India

    OpenAIRE

    Harbir Singh

    2006-01-01

    The importance of the medicinal plants sector can be gauged from the fact that herbal medicines serve the healthcare needs of about 80 per cent of the world's population. India, with approximately eight percent of world's biodiversity including plant genetic diversity with medicinal properties, has the potential of becoming a major global player in market for medicinal plants-based herbal formulations and products. However, prior to establishment of Medicinal Plants Board, there was no nodal ...

  17. Utilization of and Attitudes towards Traditional Chinese Medicine Therapies in a Chinese Cancer Hospital: A Survey of Patients and Physicians

    OpenAIRE

    McQuade, Jennifer L.; ZhiQiang Meng; Zhen Chen; Qi Wei; Ying Zhang; WenYing Bei; J. Lynn Palmer; Lorenzo Cohen

    2012-01-01

    Background. In China, the use of traditional Chinese medicine (TCM) is very popular, but little is known about how it is integrated with conventional cancer care. We conducted parallel surveys of patients and physicians on TCM utilization. Methods. Two hundred forty-five patients and 72 allopathic physicians at the Fudan University Shanghai Cancer Center completed questions on their use of and attitude towards TCM. Results. Patient mean age was 51, with 60% female. Eighty-three percent of pa...

  18. Rare and endangered plant species of the Chinese Altai Mountains

    Institute of Scientific and Technical Information of China (English)

    Marina; V.OLONOVA

    2010-01-01

    Altai (also named Altay in China) Mountain Country (Mountain System) is a unique natural region,located on the border between different floristic regimes of the Boreal and ancient Mediterranean sub-kingdoms,where distribution of plant species is actually limited. It is known to have sufficient endemic floral biodiversity in the Northern Asia. Many plants of Altai Mountain System need effective care and proper conservation measures for their survival and longer-term protection. Important Plant Area identified as the IUCN (the International Union for Conservation of Nature),specified criteria attract global attention for protection of floral biodiversity across the world. The records of 71 plant species from the Chinese Altai Mountains attributed to the criterion A and the dark conifer forests of Chinese Altai Mountains satisfied the criterion C,which may help qualify to fulfill the national obligation of the Convention on Biological Diversity.

  19. Plant part substitution--a way to conserve endangered medicinal plants?

    Science.gov (United States)

    Zschocke, S; Rabe, T; Taylor, J L; Jäger, A K; van Staden, J

    2000-07-01

    Population growth, urbanization and the unrestricted collection of medicinal plants from the wild is resulting in an over-exploitation of natural resources in southern Africa. Therefore, the management of traditional medicinal plant resources has become a matter of urgency. In southern Africa the most frequently used medicinal plants are slow-growing forest trees, bulbous and tuberous plants, with bark and underground parts being the parts mainly utilized. A strategy which would satisfy the requirements of sustainable harvesting, yet simultaneously provide for primary health care needs, would be the substitution of bark or underground parts with leaves of the same plant. This paper outlines the concept of plant substitution, using preliminary results of our recent investigations into four of the most important and most threatened South African medicinal plants - Eucomis autumnalis (bulb), Siphonochilus aethiopicus (rhizome), Ocotea bullata (bark), and Warburgia salutaris (bark) - as a demonstration of the kind of research necessary. Extracts of various plant parts were compared chemically using TLC-analysis, and pharmacologically in terms of antibacterial activity and cyclooxygenase-1 inhibition in vitro. The importance of the concept of plant part substitution as a strategy for the conservation of medicinal plants in southern Africa is discussed in terms of the results obtained. PMID:10904175

  20. Data-mining of potential antitubercular activities from molecular ingredients of traditional Chinese medicines

    Directory of Open Access Journals (Sweden)

    Salma Jamal

    2014-07-01

    Full Text Available Background. Traditional Chinese medicine encompasses a well established alternate system of medicine based on a broad range of herbal formulations and is practiced extensively in the region for the treatment of a wide variety of diseases. In recent years, several reports describe in depth studies of the molecular ingredients of traditional Chinese medicines on the biological activities including anti-bacterial activities. The availability of a well-curated dataset of molecular ingredients of traditional Chinese medicines and accurate in-silico cheminformatics models for data mining for antitubercular agents and computational filters to prioritize molecules has prompted us to search for potential hits from these datasets. Results. We used a consensus approach to predict molecules with potential antitubercular activities from a large dataset of molecular ingredients of traditional Chinese medicines available in the public domain. We further prioritized 160 molecules based on five computational filters (SMARTSfilter so as to avoid potentially undesirable molecules. We further examined the molecules for permeability across Mycobacterial cell wall and for potential activities against non-replicating and drug tolerant Mycobacteria. Additional in-depth literature surveys for the reported antitubercular activities of the molecular ingredients and their sources were considered for drawing support to prioritization. Conclusions. Our analysis suggests that datasets of molecular ingredients of traditional Chinese medicines offer a new opportunity to mine for potential biological activities. In this report, we suggest a proof-of-concept methodology to prioritize molecules for further experimental assays using a variety of computational tools. We also additionally suggest that a subset of prioritized molecules could be used for evaluation for tuberculosis due to their additional effect against non-replicating tuberculosis as well as the additional hepato