WorldWideScience

Sample records for chiiki consortium kenkyu

  1. Research and development project of regional consortiums in fiscal 1998. Research and development of regional consortium energy (development of measuring technology to aid energy conservation in electronic device manufacturing processes (design and trial production of IMI) (Report on the result in the first year)); 1998 nendo chiiki consortium energy kenkyu kaihatsu. Denshi kikirui seizo process no sho energy shien keisoku seigyo gijutsu no kaihatsu (IMI no sekkei to shisaku) (dai 1 nendo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This paper summarizes the development of intelligent micro instruments (IMI) inaugurated in fiscal 1998 as the wide-area consortium project for the Tama area. Research and development will be carried out on the following items: IMI substrate elements utilizing micro machining technology, applicable to micro sensors and micro probes, semiconductor process sensors, electronic device measuring probes, signal processing and communication circuits for wireless sensing. This paper describes the achievements during fiscal 1998. Technologies were transferred from the Mechanical Engineering Laboratory of the Agency of Industrial Science and Technology on silicon micro machining and PZT piezoelectric thin film formation. An IMI research laboratory was installed at the Tokyo Metropolitan University. In developing the IMI substrate elements, different beams applicable to sensors and probes were fabricated on a trial basis, and their mechanical properties were measured. For the semiconductor process sensors, discussions were given on micronization on a chlorine ion analyzer. In developing the electronic device measuring probes, the target was placed on measurement of in-situ characteristics of IC chips on a wafer. A prototype transmitting and receiving circuit board was fabricated for developing the wireless sensing. (NEDO)

  2. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium energy field / research and development of a reverse engineering system for local industrial articles (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium bun`ya / chiiki kogeihin muke reverse engineering system no kenkyu kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper described the fiscal 1997 result of the research on the application of local industrial article use reverse engineering (RE, it had been regarded as imitation and reproduction technology, but has recently been as a part of the production information integration). With the actual local industrial article as standard, which has features in design and was added with local traditionality, such as glass having 3D free-form surface, 3D shape information modeling technology RE is developed, and a system for direct automatic metal mold processing is established, aiming at shortening of delivery date, cost reduction and higher grade. The target of the research is Okinawa prefecture. In fiscal 1997, study was made of the speeding-up of the non-contact 3D shape information inputting (multi-point simultaneous inputting by CCD of the laser reflected light of the actual model) and the data storage technology. Cast iron was selected as molding materials, judging from reactivity/machinability with heat resistant glass. Also studied was the blend of glass materials suitable for press forming. Further, studies were proceeded with of development of intellectual cutting tools into which sensor function is integrated and of virtual reality for facilitating/accelerating the design up to metal mold manufacturing. 39 refs., 88 figs., 21 tabs.

  3. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium field/ R and D on the technology to create new organic electroluminescence devices (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium bun`ya / shin`yuki electroluminescence device no sosei gijutsu ni kansuru kenkyu kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper develops the R and D having as core creative technical seeds on the design principle of organic electroluminescence (EL) devices, aims at producing as products a polychrome display and a new energy saving type light source, develops new high efficient luminescent materials which support the production of products with high liability, and develops protective coats universally applicable to optical and electronic devices and sealing technology. In fiscal 1997, the following are commenced: 1) development of luminescent devices, 2) development of new luminescent agents, and 3) development of the mounting technology. In 1), the following are conducted: R and D for improvement of durability of EL devices, development of the process technology for polychroism, multi-coloring, and development of the large picture thin film formation technology. For the development of energy saving type high efficiency light source devices, a method is established for producing organic layers by a new wet coating method. In 3), the R and D are carried out of a method to form inorganic protective coats at low temperature and a method to highly evaluate structural defects in the protective coat. For the sealing of devices, low melting point glass and the forming technology are developed. 41 refs., 112 figs., 19 tabs.

  4. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium field / R and D on the formation of UHQ transparent conductive films (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium bun`ya / UHQ tomei dodenmaku keisei ni kansuru kenkyu kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    For the formation of low temperature process UHQ transparent conductive films, the development is made of new production process technology exceeding the limit of the conventional technology. The transparent conductive film to be used is ITO. To achieve this purpose, the following were conducted: 1) development of multi-beam UHQ thin film forming equipment, 2) fabrication of low resistance rate transparent conductive film of 10{sup -5}ohm{center_dot}cm order, 3) formation of transparent conductive film around 100degC, 4) evaluation of UHQ transparent conductive film, 5) comprehensive research/survey, etc. In 1), thin film forming equipment is developed which uses characteristics of each excitation beam such as cluster ion beam, radiation and laser. In 2), low resistance rate of 10{sup -5}ohm{center_dot}cm order is realized by ultraprecisely controlling structures of elements composing the film, using the practical equipment developed by Osaka National Research Institute. In 3), low temperature film formation around 100degC is realized by precisely controlling atomic/molecular energy in the reaction. In 4), film evaluation is conducted from a practical aspect by measuring resistance rate, transparency, hole constant, etc. of the film developed. 13 refs., 47 figs., 29 tabs.

  5. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium energy field / R and D of a task adaptation type group architecture transfer robot system, TRIPTERS (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium energy bun`ya / task tekigogata gun kosei hanso robot system TRIPTERS no kaihatsu kenkyu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper stated the fiscal 1997 result of the development of a task adaptation type group architecture transfer robot system (TRIPTERS) which can cope with changes in carrying task rapidly and flexibly. R and D were conducted mainly of various functional modules, the operation management technology which enables group architecture, and the basic design of a standardized transfer robot. As to the positioning, studied were the construction of the basic hardware of laser position measuring device, and the application method. Concerning the cooperative carrying, conducted were securing of positioning accuracy of matters to be carried, high speed heavy transfer control, and design of dead reckoning system. Relating to the operation management, passable areas were divided into more than one zones, and the effective path reservation method was constructed so that one and the same zone is not occupied. As to the environmental recognition/obstacle avoidance, developed were actual hour/distance acquisition equipment, and autonomous cars running according to the directions of the color sign recognition system by stereo CCD camera. Also conducted were the development of methods to recognize the distance to obstacles and to discriminate areas, the development of mobile sensor, and the basic experiment on running of the demonstration machine. 44 refs., 153 figs., 15 tabs.

  6. Fiscal 1998 regional consortium R and D project (Regional consortium field). Report on R and D of production technology of hybrid-type biocompatible hard tissue replacing materials (1st fiscal year); 1998 nendo chiiki konsoshiamu kenkyu kaihatsu jigyo. Chiiki konsoshiamu bun'ya (hybrid gata seitai yugo kinosei kososhiki daitai sozai seizo gijutsu no kenkyu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This project aims at development of high-strength high- biocompatible {beta}-type Ti alloy with lower modulli of elasticity composed of non-toxic elements, phosphate calcium ceramics for improving the biocompatibility and coating technology, and establishment of production technology of hybrid-type biocompatible hard tissue replacing materials. In fiscal 1998, the project promoted the following: Design of high-biocompatible {beta}-type Ti alloy materials, development of thermomechanical treatment for improving dynamic characteristics of such alloy, survey on practical melting and casting technologies and dental precision casting process, evaluation of the biocompatibility of the alloy by cytotoxicity, selection of tools for precision machining and surface finishing, control of contents, orientation and precipitation of biocompatible crystals such as {beta}- Ca(PO{sub 3}){sub 2} fibers for further improvement of the biocompatibility. This paper also outlines the survey results on the market needs, market size and market share for the feasibility of these materials. (NEDO)

  7. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium field / Development of medical equipment use super devices using micro-3D processing technology (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium bun`ya / micro sanjigen kako gijutsu ni yoru iryo kikiyo super device no kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The R and D are conducted of medical equipment use super devices using technical seeds of Mechanical Engineering Laboratory and micro-3D processing technology which was developed from precision processing technology, etc. which is integrated in the Suwa area, Nagano prefecture. For it, the following R and D are carried out: 1) development of micromechanism: DC3V driven micromotor, chemical use microtube with diameter of 0.1mm, micro-delivery mechanism of chemicals, misting mechanism of chemicals, microjoint, microconnector and cable, and microfilter. 2) development of microsensor: small size/non-contact, microflow of chemicals, and sensor to detect emission of bubble. 3) development of control system. In fiscal 1997, in 1), each element was trially made to clarify subjects. In 2), it was made clear that as flow sensor, ultrasonic type, electromagnetic type and thermal mass flow type are viable, and as bubble sensor, optical sensor is viable. In 3), the following were conducted: information collection of contactless charging circuit, and trial fabrication of liquid crystal polymer ultra thin casing. 9 refs., 84 figs., 30 tabs.

  8. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium field / R and D on process adaptive type flexible robot technology (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium bun`ya / kotei tekiogata flexible robot gijutsu ni kansuru kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    For the purpose of establishing robot technology required for the construction of a highly functional automation line with flexibility, the R and D were conducted. At Kumamoto University, a model following type power control system was studied into which polynominal trajectory formation algorithm was integrated. Also studied was damping control of robot arms in a disturbance environment. The following were further carried out: experimental verification (HIRATA Corporation) of the application of power control and intelligent control to transportation equipment production line, experimental verification (SAKURAI SEIGI Co. Ltd.) of the application of power control and intelligent control to semiconductor testing equipment, R and D (OMRON Corporation) of high accuracy force sensing and positioning system, research (Kumamoto Technopolis Foundation) on flexible arms/hands suitable for cooperative control, sensor-based skill (Electrotechnical Laboratory), research (Kyushu National Industrial Research Institute) on tactual system and tactual sensing, etc. 20 refs., 86 figs., 14 tabs.

  9. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium energy field / R and D mesoscopic organ control heat-resistant / wear-resistant metal group composite materials (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium energy bun`ya / mesoscopic fukuso soshiki seigyo tainetsu taimamosei kinzokuki fukugo zairyo no kenkyu kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Out of the R and D of mesoscopic metal group composite materials, the paper described the fiscal 1997 results. In the in-situ method as a composite material making method, elucidated to some degree were chemical composition of Fe-C-Cr-V-Nb-Mo-W-Ni base multi-dimensional alloys, and wear resistance and oxidation resistance of MC type carbide dispersion multi-phase texture crystallizing as primary crystal and eutectic. In the composite material making with ceramic fiber and alloy by the pressure infiltration method, the paper clarified the texture formation mechanism in solidification/heat treatment by a combination of Al alloys and alumina long fiber, and the relation between fiber configuration and wear resistance. By MA and MG methods as the powder metallurgy composite material making method, a composed body of {alpha}-stainless steel of Fe-12%Cr composition and M23C6 of 40-90vol% are designed for alloy composition, and powder of amorphous or hyperfine texture was fabricated. By hot pressing this, fine texture mixed with M23C6 of 1{mu}m and ferrite was obtained. Further, by mechanically alloying the powder composed of high speed steel, TiN powder and TiC powder, hyperfine texture mixed powder was fabricated. Conditions of HIP treatment of large members were also discussed. 58 refs., 124 figs., 35 tabs.

  10. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium energy field/R and D of new technology using low temperature energy for storage of agricultural products (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium energy bun`ya / teion energy wo riyoshita nosanbutsu no shinki chozo gijutsu no kenkyu kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The development was conducted of a new technology using low temperature energy in Hokkaido for storage of agricultural products. In this fiscal year, the R and D were conducted of 1) elucidation of behavior of water droplets in the air at below-freezing temperatures and technology to preserve agricultural products, 2) low temperature region high efficiency energy conversion application technology, and 3) latent heat cold storage technology. In 1), it was clarified that the electrostatic capacity system is appropriate as non-contact simple measuring device of moisture distribution in cold air. Freezing temperatures were measured of potatoes, onions and carrots produced in Hokkaido. Equipment to generate moist air at below-freezing temperatures was trially manufactured which is composed of humidifier and freezer. A relation was studied between the humidifying method and the size of particulate water droplet. In 2), an experimental device was trially fabricated of BiTe thermoelectric conversion device. An experimental device for Stirling engine power generation was assembled which was incorporated into the waste incinerator. A basic experimental device of pulse pipe refrigerator was trially fabricated. Single crystals of BiSb semiconductors were made. In 3), it was clarified that gas hydrates of CO2 and C3H8 are promising as refrigerant. 60 refs., 120 figs., 19 tabs.

  11. Achievement report for fiscal 1998 on area consortium research and development business. Area consortium for venture business development by building base for small business (abuse double protected next generation card system based on steganography); 1998 nendo venture kigyo ikuseigata chiiki consortium kenkyu kaihatsu (chusho kigyo sozo kibangata). Steganography gijutsu wo riyoshita jisedaigata fusei shiyo taju boshi guard system no kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A card system is developed using BPCS (Business Planning and Control System) steganography, with electronic data imbedded in the card. Under the system, the visual recognition of the user and the mechanical verification of the card are carried out simultaneously, with the card rejecting any abuse. In fiscal 1998, a system was built by way of trial, constituted of technologies of encoding, decoding, and packaging data into an IC (integrated circuit) card. A photograph of the user's face is attached to the card, the card carries an 8KB IC memory device, and the device stores data of the photograph of the user's face etc. A password has to be inputted before any data may be taken out. A customized key is required to display the imbedded personal data and, for the restoration of the key data, the personal key known only to the owner and the company key that is kept by the card managing company need to be collated with each other. Multiple checking is available for the prevention of abuse, which include the collation of face photographs, collation with display by inputting the password, and request for the customized key to confirm the presence of authority to read the imbedded personal data. (NEDO)

  12. Achievement report for fiscal 1998 on area consortium research and development business, 1st year. Area consortium energy research and development (molding material processing eco-system using powder lubricant); 1998 nendo chiiki consortium energy kenkyu kaihatsu bun'ya. Funtai rikei junkatsuzai wo mochiita sokeizai kako eko system no kenkyu kaihatsu (dai 1 nendo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A material processing technology demanding but low energy and cost and causing low environmental impact was developed using a powder lubricant in a closed metal die system. An inorganic powder excellent in adhesiveness as lubricant was discovered. Powder lubricants for die casting and new carbon lubricants for metal die forging were also developed. In a test in an eco-die casting system, it was found that power was better than water solution in terms of finish and energy efficiency. In the development of a metal forging system using a powder lubricant, existing graphite lubricants and new powder lubricants containing fullerene were subjected to evaluation (ring tests). Two types of graphite solutions now in use and two powder lubricants were evaluated by the ring tests, and this enabled the comprehension of powder lubricant characteristics. For the development of a die casting system requiring no lubricant, a metal die surface treatment method was found that produces a surface excellent in resisting erosion by the application of the aluminizing ion nitriding composite treatment method. In addition, wettability was compared between a PVD (physical vapor deposition)-formed nitride film and the powder lubricant constituents. The report also refers to surveys conducted for commercialization. (NEDO)

  13. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium energy field / Development of an environmentally friendly industrial cleaning system using near-critical and supercritical carbon dioxide (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium energy bun`ya / chorinkai ryutai wo mochiita kankyo chowagata kogyo senjo sochi no kaihatsu (daiichi nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    In the manufacturing process of semiconductors and in the high tech industry, cleaning is indispensable. At present, when regulation of the use of CFC which used to be much used has been decided on, the conversion to the use of substitutes for CFC cleaning is urgently needed. Transfer to cleaning by water/alcohol/hydrocarbon has been proceeded with, but there are a lot of problems. Out of the development of the cleaning method using supercritical fluid, the paper described the fiscal 1997 result. As to enhancement of efficiency and decrease in size of equipment, a cleaning experiment by high pressure CO2 around the critical point was conducted by integrating nozzle, ultrasonic generator and cavitation generator and adding solvent circulating system. Multi-purpose and energy saving of the equipment were also studied. To establish an analysis method for the cleaning degree, the contaminated component film of trace organic matter with a specified thickness was formed on the silicon wafer, and using the Fourier transform ultrared spectroscopy, a method to determine the film thickness was studied. For the function evaluation for precision machine parts and determination of optimum cleaning conditions, the cleaning/degreasing process of valves were compared with the conventional method. For the product manufacturing, the paper investigated and prepared the data in Japan and from abroad. 55 refs., 79 figs., 18 tabs.

  14. FY 2000 report on the results of the regional consortium R and D project - Regional consortium energy field. First year report. Development of the process for creation of new functional materials using electron beam excited plasma; 2000 nendo chiiki consortium kenkyu kaihatsu jigyo - chiiki consortium energy bun'ya. Denshi beam reiki plasma wo mochiita shinkino zairyo sosei process no kaihatsu (dai 1 nendo) seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The development of manufacturing technology was proceeded with for a high speed nitriding system using electron beam excited plasma device which realizes high dissociation for nitrogen molecules and controls the plasma state. By the device, the following are aimed at: high quality/high speed nitriding, formation of super-hard cubic system boron nitride (c-BN) and carbon nitride (CN) films on the surface of tools, and formation of TiO{sub 2} thin films with high infrared reflectance and environmental purification photocatalyst function. TiO{sub 2} thin films are assumed to be applied to window glass by making use of the high performance heat mirror function as well as the environmental purification function. Studies were made in the following 6 fields: 1)development of small electron beam excitation plasma source; 2) development of high speed nitrided container; 3) establishment of technology for real-time monitoring of radicals and ions; 4) design/trial manufacture of a device to form super-hard nitrided thin films; 5) development of heat mirror film formation device; 6) establishment of a method to evaluate effects of photocatalyst. (NEDO)

  15. Report of the results of the fiscal 1997 regional consortium R and D project. Regional consortium field / Development of technology to treat aquatic environment by using microorganisms fixed on carbon fabrics (abbreviation: carbon/aquatic environment project) (first fiscal year); 1997 nendo chiiki consortium kenkyu kaihatsu jigyo. Chiiki consortium bun`ya / tanso sen`i nansoshiki eno biseibutsu kochaku gensho wo riyoshita mizukankyo seibi gijutsu no kaihatsu (ryakusho: tanso mizu kankyo project) daiichi nendo seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Out of the development of technology to arrange the aquatic environment using phenomena of microorganism fixation on carbon fiber soft textures, the paper stated the fiscal 1997 result. On carbon fibers in a state of swaying in water, microorganisms in water fix in an amazingly large quantity. A catalog was compiled of 58 kinds of carbon fabrics trially woven and knitted. When carbon fiber is used as activated sludge carrier, activity of microorganism lasts more than one year. Only a little amount of surplus sludge is generated. The fixed microorganisms are more active in case of carbon fiber than in case of nylon and polyester fibers. Fiber texture models of carbon fiber fixing activated sludge groups were proposed. By pump operation, the water flow inside/outside microorganism groups is being accelerated. Several new strains of bacillus carboniphilus were isolated/identified from soil and marsh. To grasp relationships of characteristics among three elements such as the state of aquatic environment, fiber, and microorganism group, the experiment was prepared. Preliminary work is conducted to derive a simple equation for facility design, and experimental directions to obtain design conditions were proposed. 6 refs., 166 figs., 47 tabs.

  16. Achievement report for fiscal 1998 on area consortium research and development business, 1st year. Area consortium energy research and development (biofuel production by advanced function bioreactor); 1998 nendo chiiki consortium energy bun'ya. Kokino bio reactor ni yoru bio nenryo seisan ni kansuru kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Studies were made to produce ethanol directly from starch and cellulose and to collect biodiesel fuels from waste oil by an enzymatic method. For an increase in the yield of biodiesel fuel production, lipase enzymes were explored and optimum reaction conditions were sought for. Starch decomposition was quick for conversion into the target material in a system with the co-expression of amylase and glucoamylase present on the yeast cell surface layer. There was dramatically rapid progress in the increase of enzymatic activity in the cell, although dependent on cell membrane surface treatment conditions. In the generation of acetaminophen by recombinant cohesive yeasts, highly active and expressive yeasts were automatically fixed in the porous support (intelligent bioreactor) while those deactivated or dead were automatically removed. For the construction of a fuzzy control system for this reaction, basic models were investigated, built on the basis of the enzymatic model of reaction and substance balance. A high-precision structural analysis was conducted for the exploration of secondary structure stabilizing factors in protein and peptide and for the elucidation of correlations between structure and function. (NEDO)

  17. Achievement report for fiscal 1998 on area consortium research and development business. Area consortium for venture business development by building base for small business (high-efficiency superhigh-accuracy grinding technology by nano-scale in-process measurement and control using novel grinding wheel); 1998 nendo venture kigyo ikuseigata chiiki consortium kenkyu kaihatsu (chusho kigyo sozo kibangata). Shingata kensaku toishi wo mochiita nano in-process keisoku seigyo ni yoru konoritsu choseimitsu kensaku kako gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The aim is to develop a superflat grinding system for functional devices such as hard disks and magnetic heads. Cast iron powder is used as bonding material high in reacting with diamond for an increase in the anchoring power. A chemical reaction occurs to realize a strong bond between the two, producing a precision grinding wheel long in life and high in efficiency. A wheel with some hollows is also developed in which the grits have to bear more load because of the hollows, this achieving grinding efficiency five times higher than that of other types of the same grit size. A system is developed, provided with a constant pressure mechanism for the grinding direction and constant travel mechanism normal to the work surface. Using the constant pressure system, the grinding speed depends on the wheel grinding capability, and then the wheel is allowed to exhibits its best. The system suffers less clogging than the conventional ones. The specific grinding energy which is the index of the match between the wheel and the work may be determined, and this enables prompt condition optimization. It is proved that the wheel with hollows is remarkably higher in grinding capability than wheels of the same grit size on the market. The two are found to be alike in achieving top-class finish in terms of surface coarseness and flatness. (NEDO)

  18. International Lymphoma Epidemiology Consortium

    Science.gov (United States)

    The InterLymph Consortium, or formally the International Consortium of Investigators Working on Non-Hodgkin's Lymphoma Epidemiologic Studies, is an open scientific forum for epidemiologic research in non-Hodgkin's lymphoma.

  19. Report on a feasibility study of making an international joint research on energy in the Asia region; Asia chiiki kokusai kyodo kenkyu kanosei chosa hokokusho. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    A survey was conducted on the energy situation in Thailand, Indonesia, Malaysia, the Philippines and India, and a possibility of making an international joint research. Thailand has sharply increased investments from Europe and the U.S. since 1985, and has been making a rapid industrialization. As to the energy policy, it is important to secure the stable supply and stabilize the price. Indonesia has been rapidly increasing energy consumption in accordance with the recent economic growth, and is fear of becoming a net oil importing country in the near future. They are taking a policy for securing as much domestic oil and gas as possible. Malaysia has been keeping a high growth of over 8% per year for the past 8 years and rapidly increased energy demand. It is expected that they will maintain a high level of the development of energy resources. In the Philippines, the industrial energy is mostly coal, but electricity expected in future is from the oil-fueled power generation. The stable import of oil is a problem. 45 figs., 51 tabs.

  20. Fiscal 1997 report on a feasibility study of international joint researches in the Asian region; 1997 nendo chosa hokokusho (Asia chiiki kokusai kyodo kenkyu kanosei chosa (4)hokokusho)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    It is thought that the energy consumption in Asian countries with ASEAN and China as center will a marked growth also in future together with a rapid economic growth, but harmony with environmental problems and economic growth is being taken as a serious problem. This is an important issue also to Japan from viewpoints of secure energy supply and regional response to the environmental issue. Accordingly, strongly desired is positive response to global environmental issues and promotion in development/spread of new energy/energy conservation in these countries. For the spread of the technologies, actual construction/operation of plants by joint researches with Japan are effective from aspects of personnel raising, technical improvement, PR effects, etc. This is also helpful for Japan in terms of technological development because Japan can also get the unobtainable data from the operation under appropriate conditions. This is a report on the studies of the trends of global environmental problems in Thailand, Indonesia, Malaysia, the Philippines, India and China. 3 figs., 72 tabs.

  1. Radiogenomics Consortium (RGC)

    Science.gov (United States)

    The Radiogenomics Consortium's hypothesis is that a cancer patient's likelihood of developing toxicity to radiation therapy is influenced by common genetic variations, such as single nucleotide polymorphisms (SNPs).

  2. NCI Cohort Consortium Membership

    Science.gov (United States)

    The NCI Cohort Consortium membership is international and includes investigators responsible for more than 40 high-quality cohorts who are studying large and diverse populations in more than 15 different countries.

  3. NCI Cohort Consortium

    Science.gov (United States)

    The NCI Cohort Consortium is an extramural-intramural partnership formed by the National Cancer Institute to address the need for large-scale collaborations to pool the large quantity of data and biospecimens necessary to conduct a wide range of cancer studies.

  4. The Genomic Standards Consortium

    DEFF Research Database (Denmark)

    Field, Dawn; Amaral-Zettler, Linda; Cochrane, Guy;

    2011-01-01

    Standards Consortium (GSC), an open-membership organization that drives community-based standardization activities, Here we provide a short history of the GSC, provide an overview of its range of current activities, and make a call for the scientific community to join forces to improve the quality...

  5. IPD-Work consortium

    DEFF Research Database (Denmark)

    Kivimäki, Mika; Singh-Manoux, Archana; Virtanen, Marianna;

    2015-01-01

    of countries. The aim of the consortium is to estimate reliably the associations of work-related psychosocial factors with chronic diseases, disability, and mortality. Our findings are highly cited by the occupational health, epidemiology, and clinical medicine research community. However, some of......Established in 2008 and comprising over 60 researchers, the IPD-Work (individual-participant data meta-analysis in working populations) consortium is a collaborative research project that uses pre-defined meta-analyses of individual-participant data from multiple cohort studies representing a range...... the IPD-Work's findings have also generated disagreement as they challenge the importance of job strain as a major target for coronary heart disease (CHD) prevention, this is reflected in the critical discussion paper by Choi et al (1). In this invited reply to Choi et al, we aim to (i) describe how...

  6. Kansas Wind Energy Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Gruenbacher, Don [Kansas State Univ., Manhattan, KS (United States)

    2015-12-31

    This project addresses both fundamental and applied research problems that will help with problems defined by the DOE “20% Wind by 2030 Report”. In particular, this work focuses on increasing the capacity of small or community wind generation capabilities that would be operated in a distributed generation approach. A consortium (KWEC – Kansas Wind Energy Consortium) of researchers from Kansas State University and Wichita State University aims to dramatically increase the penetration of wind energy via distributed wind power generation. We believe distributed generation through wind power will play a critical role in the ability to reach and extend the renewable energy production targets set by the Department of Energy. KWEC aims to find technical and economic solutions to enable widespread implementation of distributed renewable energy resources that would apply to wind.

  7. Nuclear Technology Education Consortium

    International Nuclear Information System (INIS)

    To reinforce the government efforts toward the restoration of nuclear education health, a new concept in post-graduate level training for the nuclear sector has been developed by a strong consortium of UK universities and HE institutions under the title Nuclear Technology Education Consortium (NTEC). The basis of this consortium were designed to meet the UK projected nuclear skills requirements in decommissioning and cleanup, reactor technology, fusion and nuclear medicine. The structure and content of the programme, which leads to qualifications up to master's level in nuclear science and technology, was established following extensive consultations with the UK nuclear sector, including industry, regulators, MoD, NDA, Government Departments and the Cogent Sector Skills Council. The programme is coordinated by the Dalton Nuclear Institute at The University of Manchester. This programme has been approved by the Institution of Mechanical Engineers. Following are the key features of this consortium: - It was only designed to fulfil the needs nuclear sector; - It offers subjects in broad spectrum, from reactor theory through decommissioning to waste disposal and storage, the subject matter being presented by leading specialists in their field; - Each topic is presented in short course format which is ideal for employees within the industry; - It offers part-time basis over a period of three years as well as full-time in one year post-graduate courses in nuclear science and technology; - This programme also covers the Post-graduate Diploma or Post-graduate Certificate opportunity for students; - Individual subjects are presented in 'short course' modular format, providing excellent access to the programme for engineers and managers in full-time employment who wish to advance their skill and knowledge base; - The core of each module is one week of direct teaching at the relevant institution, minimizing the time away from the workplace for an employee whilst maximizing

  8. The Neuroscience Peer Review Consortium

    Directory of Open Access Journals (Sweden)

    Maunsell John HR

    2009-03-01

    Full Text Available Abstract As the Neuroscience Peer Review Consortium (NPRC ends its first year, it is worth looking back to see how the experiment has worked. In order to encourage dissemination of the details outlined in this Editorial, it will also be published in other journals in the Neuroscience Peer Review Consortium.

  9. Hawaii Space Grant Consortium

    Science.gov (United States)

    Flynn, Luke P.

    2005-01-01

    The Hawai'i Space Grant Consortium is composed of ten institutions of higher learning including the University of Hawai'i at Manoa, the University of Hawai'i at Hilo, the University of Guam, and seven Community Colleges spread over the 4 main Hawaiian islands. Geographic separation is not the only obstacle that we face as a Consortium. Hawai'i has been mired in an economic downturn due to a lack of tourism for almost all of the period (2001 - 2004) covered by this report, although hotel occupancy rates and real estate sales have sky-rocketed in the last year. Our challenges have been many including providing quality educational opportunities in the face of shrinking State and Federal budgets, encouraging science and technology course instruction at the K-12 level in a public school system that is becoming less focused on high technology and more focused on developing basic reading and math skills, and assembling community college programs with instructors who are expected to teach more classes for the same salary. Motivated people can overcome these problems. Fortunately, the Hawai'i Space Grant Consortium (HSGC) consists of a group of highly motivated and talented individuals who have not only overcome these obstacles, but have excelled with the Program. We fill a critical need within the State of Hawai'i to provide our children with opportunities to pursue their dreams of becoming the next generation of NASA astronauts, engineers, and explorers. Our strength lies not only in our diligent and creative HSGC advisory board, but also with Hawai'i's teachers, students, parents, and industry executives who are willing to invest their time, effort, and resources into Hawai'i's future. Our operational philosophy is to FACE the Future, meaning that we will facilitate, administer, catalyze, and educate in order to achieve our objective of creating a highly technically capable workforce both here in Hawai'i and for NASA. In addition to administering to programs and

  10. Advanced Lab Consortium ``Conspiracy''

    Science.gov (United States)

    Reichert, Jonathan F.

    2006-03-01

    Advanced Laboratory instruction is a time-honored and essential element of an undergraduate physics education. But, from my vantage point, it has been neglected by the two major professional societies, APS and AAPT. At some schools, it has been replaced by ``research experiences,'' but I contend that very few of these experiences in the research lab, particularly in the junior year, deliver what they promise. It is time to focus the attention of APS, AAPT, and the NSF on the advanced lab. We need to create an Advanced Lab Consortium (ALC) of faculty and staff to share experiments, suppliers, materials, pedagogy, ideas, in short to build a professional network for those committed to advanced lab instruction. The AAPT is currently in serious discussions on this topic and my company stands ready with both financial and personnel resources to support the effort. This talk is a plea for co-conspirators.

  11. Gas Storage Technology Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison; Sharon L. Elder

    2007-06-30

    Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feet over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is crucial in meeting the needs of these new markets. To address the gas storage needs of the natural gas industry, an industry-driven consortium was created--the Gas Storage Technology Consortium (GSTC). The objective of the GSTC is to provide a means to accomplish industry-driven research and development designed to enhance the operational flexibility and deliverability of the nation's gas storage system, and provide a cost-effective, safe, and reliable supply of natural gas to meet domestic demand. This report addresses the activities for the quarterly period of April 1, 2007 through June 30, 2007. Key activities during this time period included: (1) Organizing and hosting the 2007 GSTC Spring Meeting; (2) Identifying the 2007 GSTC projects, issuing award or declination letters, and begin drafting subcontracts; (3) 2007 project mentoring teams identified; (4) New NETL Project Manager; (5) Preliminary planning for the 2007 GSTC Fall Meeting; (6) Collecting and compiling the 2005 GSTC project final reports; and (7) Outreach and communications.

  12. Gas Storage Technology Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison; Sharon L. Elder

    2006-05-10

    Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services, and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feet (TCF) over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is critical in meeting the needs of these new markets. In order to address the gas storage needs of the natural gas industry, an industry-driven consortium was created--the Gas Storage Technology Consortium (GSTC). The objective of the GSTC is to provide a means to accomplish industry-driven research and development designed to enhance operational flexibility and deliverability of the Nation's gas storage system, and provide a cost effective, safe, and reliable supply of natural gas to meet domestic demand. This report addresses the activities for the quarterly period of January 1, 2006 through March 31, 2006. Activities during this time period were: (1) Organize and host the 2006 Spring Meeting in San Diego, CA on February 21-22, 2006; (2) Award 8 projects for co-funding by GSTC for 2006; (3) New members recruitment; and (4) Improving communications.

  13. Nuclear Fabrication Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Levesque, Stephen [EWI, Columbus, OH (United States)

    2013-04-05

    This report summarizes the activities undertaken by EWI while under contract from the Department of Energy (DOE) Office of Nuclear Energy (NE) for the management and operation of the Nuclear Fabrication Consortium (NFC). The NFC was established by EWI to independently develop, evaluate, and deploy fabrication approaches and data that support the re-establishment of the U.S. nuclear industry: ensuring that the supply chain will be competitive on a global stage, enabling more cost-effective and reliable nuclear power in a carbon constrained environment. The NFC provided a forum for member original equipment manufactures (OEM), fabricators, manufacturers, and materials suppliers to effectively engage with each other and rebuild the capacity of this supply chain by : Identifying and removing impediments to the implementation of new construction and fabrication techniques and approaches for nuclear equipment, including system components and nuclear plants. Providing and facilitating detailed scientific-based studies on new approaches and technologies that will have positive impacts on the cost of building of nuclear plants. Analyzing and disseminating information about future nuclear fabrication technologies and how they could impact the North American and the International Nuclear Marketplace. Facilitating dialog and initiate alignment among fabricators, owners, trade associations, and government agencies. Supporting industry in helping to create a larger qualified nuclear supplier network. Acting as an unbiased technology resource to evaluate, develop, and demonstrate new manufacturing technologies. Creating welder and inspector training programs to help enable the necessary workforce for the upcoming construction work. Serving as a focal point for technology, policy, and politically interested parties to share ideas and concepts associated with fabrication across the nuclear industry. The report the objectives and summaries of the Nuclear Fabrication Consortium

  14. Gas Storage Technology Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison; Sharon L. Elder

    2006-09-30

    Gas storage is a critical element in the natural gas industry. Producers, transmission and distribution companies, marketers, and end users all benefit directly from the load balancing function of storage. The unbundling process has fundamentally changed the way storage is used and valued. As an unbundled service, the value of storage is being recovered at rates that reflect its value. Moreover, the marketplace has differentiated between various types of storage services, and has increasingly rewarded flexibility, safety, and reliability. The size of the natural gas market has increased and is projected to continue to increase towards 30 trillion cubic feet (TCF) over the next 10 to 15 years. Much of this increase is projected to come from electric generation, particularly peaking units. Gas storage, particularly the flexible services that are most suited to electric loads, is critical in meeting the needs of these new markets. In order to address the gas storage needs of the natural gas industry, an industry-driven consortium was created-the Gas Storage Technology Consortium (GSTC). The objective of the GSTC is to provide a means to accomplish industry-driven research and development designed to enhance operational flexibility and deliverability of the Nation's gas storage system, and provide a cost effective, safe, and reliable supply of natural gas to meet domestic demand. This report addresses the activities for the quarterly period of July 1, 2006 to September 30, 2006. Key activities during this time period include: {lg_bullet} Subaward contracts for all 2006 GSTC projects completed; {lg_bullet} Implement a formal project mentoring process by a mentor team; {lg_bullet} Upcoming Technology Transfer meetings: {sm_bullet} Finalize agenda for the American Gas Association Fall Underground Storage Committee/GSTC Technology Transfer Meeting in San Francisco, CA. on October 4, 2006; {sm_bullet} Identify projects and finalize agenda for the Fall GSTC Technology

  15. Gas Storage Technology Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Joel Morrison; Elizabeth Wood; Barbara Robuck

    2010-09-30

    The EMS Energy Institute at The Pennsylvania State University (Penn State) has managed the Gas Storage Technology Consortium (GSTC) since its inception in 2003. The GSTC infrastructure provided a means to accomplish industry-driven research and development designed to enhance the operational flexibility and deliverability of the nation's gas storage system, and provide a cost-effective, safe, and reliable supply of natural gas to meet domestic demand. The GSTC received base funding from the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL) Oil & Natural Gas Supply Program. The GSTC base funds were highly leveraged with industry funding for individual projects. Since its inception, the GSTC has engaged 67 members. The GSTC membership base was diverse, coming from 19 states, the District of Columbia, and Canada. The membership was comprised of natural gas storage field operators, service companies, industry consultants, industry trade organizations, and academia. The GSTC organized and hosted a total of 18 meetings since 2003. Of these, 8 meetings were held to review, discuss, and select proposals submitted for funding consideration. The GSTC reviewed a total of 75 proposals and committed co-funding to support 31 industry-driven projects. The GSTC committed co-funding to 41.3% of the proposals that it received and reviewed. The 31 projects had a total project value of $6,203,071 of which the GSTC committed $3,205,978 in co-funding. The committed GSTC project funding represented an average program cost share of 51.7%. Project applicants provided an average program cost share of 48.3%. In addition to the GSTC co-funding, the consortium provided the domestic natural gas storage industry with a technology transfer and outreach infrastructure. The technology transfer and outreach were conducted by having project mentoring teams and a GSTC website, and by working closely with the Pipeline Research Council International (PRCI) to

  16. COnsortium of METabolomics Studies (COMETS)

    Science.gov (United States)

    The COnsortium of METabolomics Studies (COMETS) is an extramural-intramural partnership that promotes collaboration among prospective cohort studies that follow participants for a range of outcomes and perform metabolomic profiling of individuals.

  17. The Cambridge Infectious Diseases Consortium

    OpenAIRE

    Wood, James

    2010-01-01

    The Cambridge Infectious Diseases Consortium (CIDC) was established to provide a multi-institutional, world class quality environment for infectious disease research addressing important questions and for the recruitment and training of high quality veterinarians into careers in infectious disease research. The programme has been a demonstrable success in achieving these overall aims. The institutions that have played a key role in the consortium include the Department of Veterinary Medic...

  18. REALIZATION OF CONSORTIUM PROJECTS

    OpenAIRE

    Łukasik, Jolanta

    2010-01-01

    В статье описаны институционные проблемы и взаимоотношения внутри консорциум во время реализации проектов. Представлены избранные конфликтные ситуации, которые могут появиться в проектных коллективах, также описан фактор риска, который может появляться во время работы с проектом.The article describes the institutional problems and relationships within the consortium during the realization of projects. Selected conflict situations that may arise in project teams and risk factor that may appear...

  19. FY 1997 report on the research for construction of NEDO`s vision. Regional environment and international collaboration; 1997 nendo chosa hokokusho (NEDO vision sakutei ni muketa chosa kenkyu). Chiiki kankyo to kokusai kyoryoku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    It is necessary for NEDO to transfer the energy technology to developing countries and conduct collaborations with them efficiently. First of all, environments of the community were analyzed from a viewpoint of natural environment, social and cultural environment, and industrial and economic environment. Then, this report outlines the organizations of domestic and international aid agencies which have potentials to conduct alliance and collaboration with NEDO, and also illustrates their activities including financing and technology exchange, regional activities, and progress of activities. Alliances and collaborations with NGOs of each international organization were analyzed on the aspect of the fields and know-how of alliance with NGOs, selection standards of NGOs and necessary systems and organizations to make effective alliance and collaboration with NGOs, and some case studies were taken. Organization, purposes and activities of NGOs in Asian countries are introduced, and their current situations are illustrated. Finally, some proposals were offered to make alliances and collaborations with aid agencies and NGOs. They are concerned about the fields and know-how of alliance with NGOs, selection standards of NGOs and necessary systems and organizations to make effective alliance and collaboration with NGOs. 44 figs., 8 tabs.

  20. Study on the characteristics of earthquake ground motion in the Hanshin area based on microtremor measurements; Bido kansoku ni motozuku Hanshin chiiki no jiban shindo tokusei ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, H.; Seo, K.; Yamanaka, H. [Tokyo Institute of Technology, Tokyo (Japan)

    1997-05-27

    The Hyogoken-nanbu earthquake in 1995 was a local earthquake that has hit directly a large urban area, having caused damages the greatest since the War mainly in the city of Kobe. The present study has noticed the areas of Sumiyoshi, Nada Ward, Kobe City and Nanbu, Nishinomiya City where damages show different distribution; elucidated the characteristics of earthquake ground motion based on microtremor measurements; and discussed the relation thereof with the earthquake damage distribution. It was verified that microtremors and seismic motions are in rough agreement in the Sumiyoshi area, by comparing and discussing the spectrum ratio between the microtremors and the seismic motions. No correspondence was recognized in the Sumiyoshi area between distribution of the average microtremor spectrum ratio with cycles of 0.2 to 0.8 second and distribution of damages caused by the Hyogoken-nanbu earthquake. The ground characteristics evaluation alone is insufficient to explain distribution of the damages in a relatively wide range in the city of Nishinomiya, for which effects of distance decay should be taken into consideration. 6 refs., 7 figs.

  1. Combustion Byproducts Recycling Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Paul Ziemkiewicz; Tamara Vandivort; Debra Pflughoeft-Hassett; Y. Paul Chugh; James Hower

    2008-08-31

    The Combustion Byproducts Recycling Consortium (CBRC) program was developed as a focused program to remove and/or minimize the barriers for effective management of over 123 million tons of coal combustion byproducts (CCBs) annually generated in the USA. At the time of launching the CBRC in 1998, about 25% of CCBs were beneficially utilized while the remaining was disposed in on-site or off-site landfills. During the ten (10) year tenure of CBRC (1998-2008), after a critical review, 52 projects were funded nationwide. By region, the East, Midwest, and West had 21, 18, and 13 projects funded, respectively. Almost all projects were cooperative projects involving industry, government, and academia. The CBRC projects, to a large extent, successfully addressed the problems of large-scale utilization of CCBs. A few projects, such as the two Eastern Region projects that addressed the use of fly ash in foundry applications, might be thought of as a somewhat smaller application in comparison to construction and agricultural uses, but as a novel niche use, they set the stage to draw interest that fly ash substitution for Portland cement might not attract. With consideration of the large increase in flue gas desulfurization (FGD) gypsum in response to EPA regulations, agricultural uses of FGD gypsum hold promise for large-scale uses of a product currently directed to the (currently stagnant) home construction market. Outstanding achievements of the program are: (1) The CBRC successfully enhanced professional expertise in the area of CCBs throughout the nation. The enhanced capacity continues to provide technology and information transfer expertise to industry and regulatory agencies. (2) Several technologies were developed that can be used immediately. These include: (a) Use of CCBs for road base and sub-base applications; (b) full-depth, in situ stabilization of gravel roads or highway/pavement construction recycled materials; and (c) fired bricks containing up to 30%-40% F

  2. The ocean sampling day consortium

    DEFF Research Database (Denmark)

    Kopf, Anna; Bicak, Mesude; Kottmann, Renzo;

    2015-01-01

    Ocean Sampling Day was initiated by the EU-funded Micro B3 (Marine Microbial Biodiversity, Bioinformatics, Biotechnology) project to obtain a snapshot of the marine microbial biodiversity and function of the world’s oceans. It is a simultaneous global mega-sequencing campaign aiming to generate...... the largest standardized microbial data set in a single day. This will be achievable only through the coordinated efforts of an Ocean Sampling Day Consortium, supportive partnerships and networks between sites. This commentary outlines the establishment, function and aims of the Consortium and describes our...

  3. Brain Tumor Epidemiology Consortium (BTEC)

    Science.gov (United States)

    The Brain Tumor Epidemiology Consortium is an open scientific forum organized to foster the development of multi-center, international and inter-disciplinary collaborations that will lead to a better understanding of the etiology, outcomes, and prevention of brain tumors.

  4. Corn in consortium with forages

    Directory of Open Access Journals (Sweden)

    Cássia Maria de Paula Garcia

    2013-12-01

    Full Text Available The basic premises for sustainable agricultural development with focus on rural producers are reducing the costs of production and aggregation of values through the use crop-livestock system (CLS throughout the year. The CLS is based on the consortium of grain crops, especially corn with tropical forages, mainly of the genus Panicum and Urochloa. The study aimed to evaluate the grain yield of irrigated corn crop intercropped with forage of the genus Panicum and Urochloa. The experiment was conducted at the Fazenda de Ensino, Pesquisa e Extensão – FEPE  of the Faculdade de Engenharia - UNESP, Ilha Solteira in an Oxisol in savannah conditions and in the autumn winter of 2009. The experimental area was irrigated by a center pivot and had a history of no-tillage system for 8 years. The corn hybrid used was simple DKB 390 YG at distances of 0.90 m. The seeds of grasses were sown in 0.34 m spacing in the amount of 5 kg ha-1, they were mixed with fertilizer minutes before sowing  and placed in a compartment fertilizer seeder and fertilizers were mechanically deposited in the soil at a depth of 0.03 m. The experimental design used was a randomized block with four replications and five treatments: Panicum maximum cv. Tanzania sown during the nitrogen fertilization (CTD of the corn; Panicum maximum cv. Mombaça sown during the nitrogen fertilization (CMD of the corn; Urochloa brizantha cv. Xaraés sown during the occasion of nitrogen fertilization (CBD of the corn; Urochloa ruziziensis cv. Comumsown during the nitrogen fertilization (CRD of the corn and single corn (control. The production components of corn: plant population per hectare (PlPo, number of ears per hectare (NE ha-1, number of rows per ear (NRE, number of kernels per row on the cob (NKR, number of grain in the ear (NGE and mass of 100 grains (M100G were not influenced by consortium with forage. Comparing grain yield (GY single corn and maize intercropped with forage of the genus Panicum

  5. John Glenn Biomedical Engineering Consortium

    Science.gov (United States)

    Nall, Marsha

    2004-01-01

    The John Glenn Biomedical Engineering Consortium is an inter-institutional research and technology development, beginning with ten projects in FY02 that are aimed at applying GRC expertise in fluid physics and sensor development with local biomedical expertise to mitigate the risks of space flight on the health, safety, and performance of astronauts. It is anticipated that several new technologies will be developed that are applicable to both medical needs in space and on earth.

  6. The AGTSR consortium: An update

    Energy Technology Data Exchange (ETDEWEB)

    Fant, D.B.; Golan, L.P. [Clemson Univ., SC (United States)

    1995-10-01

    The Advanced Gas Turbine Systems Research (AGTSR) program is a collaborative University-Industry R&D Consortium that is managed and administered by the South Carolina Energy R&D Center. AGTSR is a nationwide consortium dedicated to advancing land-based gas turbine systems for improving future power generation capability. It directly supports the technology-research arm of the ATS program and targets industry-defined research needs in the areas of combustion, heat transfer, materials, aerodynamics, controls, alternative fuels, and advanced cycles. The consortium is organized to enhance U.S. competitiveness through close collaboration with universities, government, and industry at the R&D level. AGTSR is just finishing its third year of operation and is sponsored by the U.S. DOE - Morgantown Energy Technology Center. The program is scheduled to continue past the year 2000. At present, there are 78 performing member universities representing 36 states, and six cost-sharing U.S. gas turbine corporations. Three RFP`s have been announced and the fourth RFP is expected to be released in December, 1995. There are 31 research subcontracts underway at performing member universities. AGTSR has also organized three workshops, two in combustion and one in heat transfer. A materials workshop is in planning and is scheduled for February, 1996. An industrial internship program was initiated this past summer, with one intern positioned at each of the sponsoring companies. The AGTSR consortium nurtures close industry-university-government collaboration to enhance synergism and the transition of research results, accelerate and promote evolutionary-revolutionary R&D, and strives to keep a prominent U.S. industry strong and on top well into the 21st century. This paper will present the objectives and benefits of the AGTSR program, progress achieved to date, and future planned activity in fiscal year 1996.

  7. Corn in consortium with forages

    OpenAIRE

    Cássia Maria de Paula Garcia; Marcelo Andreotti; Marcelo Carvalho Minhoto Teixeira Filho; Keny Samejima Mascarenha Lopes; Ciniro Costa; Erikelly Aline Ribeiro de Santana

    2013-01-01

    The basic premises for sustainable agricultural development with focus on rural producers are reducing the costs of production and aggregation of values through the use crop-livestock system (CLS) throughout the year. The CLS is based on the consortium of grain crops, especially corn with tropical forages, mainly of the genus Panicum and Urochloa. The study aimed to evaluate the grain yield of irrigated corn crop intercropped with forage of the genus Panicum and Urochloa. The experiment was c...

  8. Appalachian clean coal technology consortium

    Energy Technology Data Exchange (ETDEWEB)

    Kutz, K.; Yoon, Roe-Hoan [Virginia Polytechnic Institute and State Univ., Blacksburg, VA (United States)

    1995-11-01

    The Appalachian Clean Coal Technology Consortium (ACCTC) has been established to help U.S. coal producers, particularly those in the Appalachian region, increase the production of lower-sulfur coal. The cooperative research conducted as part of the consortium activities will help utilities meet the emissions standards established by the 1990 Clean Air Act Amendments, enhance the competitiveness of U.S. coals in the world market, create jobs in economically-depressed coal producing regions, and reduce U.S. dependence on foreign energy supplies. The research activities will be conducted in cooperation with coal companies, equipment manufacturers, and A&E firms working in the Appalachian coal fields. This approach is consistent with President Clinton`s initiative in establishing Regional Technology Alliances to meet regional needs through technology development in cooperation with industry. The consortium activities are complementary to the High-Efficiency Preparation program of the Pittsburgh Energy Technology Center, but are broader in scope as they are inclusive of technology developments for both near-term and long-term applications, technology transfer, and training a highly-skilled work force.

  9. PanScan, the Pancreatic Cancer Cohort Consortium, and the Pancreatic Cancer Case-Control Consortium

    Science.gov (United States)

    The Pancreatic Cancer Cohort Consortium consists of more than a dozen prospective epidemiologic cohort studies within the NCI Cohort Consortium, whose leaders work together to investigate the etiology and natural history of pancreatic cancer.

  10. Tri-District Arts Consortium Summer Program.

    Science.gov (United States)

    Kirby, Charlotte O.

    1990-01-01

    The Tri-District Arts Consortium in South Carolina was formed to serve artistically gifted students in grades six-nine. The consortium developed a summer program offering music, dance, theatre, and visual arts instruction through a curriculum of intense training, performing, and hands-on experiences with faculty members and guest artists. (JDD)

  11. Introduction to Neuroscience Peer Review Consortium

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Introduction The Neuroscience Peer Review Consortium is an alliance of neuroscience journals that have agreed to accept manuscript reviews from other members of the Consortium.Its goals are to support efficient and thorough peer review of original research in neuroscience, speed the publication of research reports, and reduce the burden on peer reviewers.

  12. Building a local research consortium.

    Science.gov (United States)

    Martin, P A

    1994-05-01

    Although state, regional, and national networking often are critical to the nurse researchers, local support that is broader than what is found in any single agency may be the foundation needed by clinicians who want "more" research than that prescribed by their current role. More formal consortiums have successfully implemented a variety of research projects and are another possibility to explore (Beaman & Strader, 1990; Bolton, 1991; Chenitz et al., 1990; Keefe et al., 1988; Thiele, 1989). Another option is some state nurses' associations that have formal research assemblies (eg., Ohio Nurses Association, Assembly of Nurse Researchers). However, forming a local, less formal group with a few expert advisors may supply the energy and momentum necessary for both using and conducting research at a grassroots level. The expert advisors should be research-trained nurses (almost always with a PhD or DNS) who are active group members. Although Fitzpatrick encouraged collaborative research and writing early in the history of Applied Nursing Research (Fitzpatrick, 1989), in 1993 approximately two thirds of the articles in Applied Nursing Research still were single authored. Nurses are not using collaboration to its fullest extent. An informal group in one community has been one way to release the scholarship that was latent in many nurses. PMID:8031105

  13. The LBNL/JSU/AGMUS Science Consortium

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    This report discusses the 11 year of accomplishments of the science consortium of minority graduates from Jackson State University and Ana G. Mendez University at the Lawrence Berkeley National Laboratory.

  14. CFD analysis of pump consortium impeller

    Science.gov (United States)

    Cheng, Gary C.; Chen, Y. S.; Williams, R. W.

    1992-01-01

    Current design of high performance turbopumps for rocket engines requires effective and robust analytical tools to provide design impact in a productive manner. The main goal of this study is to develop a robust and effective computational fluid dynamics (CFD) pump model for general turbopump design and analysis applications. A Navier-Stokes flow solver, FDNS, embedded with the extended k-epsilon turbulence model and with appropriate moving interface boundary conditions, is developed to analyze turbulent flows in the turbomachinery devices. The FDNS code was benchmarked with its numerical predictions of the pump consortium inducer, and provides satisfactory results. In the present study, a CFD analysis of the pump consortium impeller will be conducted with the application of the FDNS code. The pump consortium impeller, with partial blades, is the new design concept of the advanced rocket engine.

  15. COAL ASH RESOURCES RESEARCH CONSORTIUM

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-12-01

    The Coal Ash Resources Research Consortium (CARRC, pronounced �cars�) is the core coal combustion by-product (CCB) research group at the Energy & Environmental Research Center (EERC). CARRC focuses on performing fundamental and applied scientific and engineering research emphasizing the environmentally safe, economical use of CCBs. CARRC member organizations, which include utilities and marketers, are key to developing industry-driven research in the area of CCB utilization and ensuring its successful application. CARRC continued the partnership of industry partners, university researchers, and the U.S. Department of Energy (DOE) addressing needs in the CCB industry through technical research and development projects. Technology transfer also continued through distribution and presentation of the results of research activities to appropriate audiences, with emphasis on reaching government agency representatives and end users of CCBs. CARRC partners have evolved technically and have jointly developed an understanding of the layers of social, regulatory, legal, and competition issues that impact the success of CCB utilization as applies to the CCB industry in general and to individual companies. Many CARRC tasks are designed to provide information on CCB performance including environmental performance, engineering performance, favorable economics, and improved life cycle of products and projects. CARRC activities from 1993�1998 included a variety of research tasks, with primary work performed in laboratory tasks developed to answer specific questions or evaluate important fundamental properties of CCBs. The tasks summarized in this report are 1) The Demonstration of CCB Use in Small Construction Projects, 2) Application of CCSEM (computer-controlled scanning electron microscopy) for Coal Combustion By-Product Characterization, 3) Development of a Procedure to Determine Heat of Hydration for Coal Combustion By-Products, 4) Investigation of the Behavior of High

  16. The Yamato-793605 martian meteorite consortium

    OpenAIRE

    Kojima,Hideyasu/Miyamoto,Masamichi/Warren,Paul H.

    1997-01-01

    We describe the consortium that has been organized to coordinate study of the Yamato-793605 shergottitic peridotite, a 16-g meteorite of presumed martian origin. Y-793605 is similar to two other Antarctic martian meteorites, ALH-77005 and LEW88516. One of the most important goals of the consortium is to determine how the cosmic-ray exposure history of Y-793605 compares with those of ALH-77005 and LEW88516. An aphanitic-glassy shock melted lithology that constitutes, as scattered veins and glo...

  17. The COPD Biomarker Qualification Consortium (CBQC)

    DEFF Research Database (Denmark)

    Casaburi, Richard; Celli, Bartolome; Crapo, James;

    2013-01-01

    industry and academia conducted a workshop to survey the available information that could contribute to new tools. Based on this, a collaborative project, the COPD Biomarkers Qualification Consortium, was initiated. The Consortium in now actively preparing integrated data sets from existing resources......, and no interested party has been in a position to undertake such a process. In order to facilitate the development of novel tools to assess new treatments, the Food and Drug Administration, in collaboration with the COPD Foundation, the National Heart Lung and Blood Institute and scientists from the pharmaceutical...

  18. Primary Immune Deficiency Treatment Consortium (PIDTC) report

    NARCIS (Netherlands)

    L.M. Griffith (Linda); M. Cowan (Morton); L.D. Notarangelo (Luigi Daniele); R. Kohn (Robert); J. Puck (Jennifer); S.-Y. Pai (Sung-Yun); B. Ballard (Barbara); S.C. Bauer (Sarah); J. Bleesing (Jack); M. Boyle (Marcia); R.W. Brower (Ronald); R.H. Buckley (Rebecca); M. van der Burg (Mirjam); L.M. Burroughs (Lauri); F. Candotti (Fabio); A. Cant (Andrew); T. Chatila (Talal); C. Cunningham-Rundles (Charlotte); M.C. Dinauer (Mary); J. Dvorak (Jennie); A. Filipovich (Alexandra); L.A. Fleisher (Lee); H.B. Gaspar (Bobby); T. Gungor (Tayfun); E. Haddad (Elie); E. Hovermale (Emily); F. Huang (Faith); A. Hurley (Alan); M. Hurley (Mary); S.K. Iyengar (Sudha); E.M. Kang (Elizabeth); B.R. Logan (Brent); J.R. Long-Boyle (Janel); H. Malech (Harry); S.A. McGhee (Sean); S. Modell (Sieglinde); S. Modell (Sieglinde); H.D. Ochs (Hans); R.J. O'Reilly (Richard); R. Parkman (Robertson); D. Rawlings (D.); J.M. Routes (John); P. Shearer (P.); T.N. Small (Trudy); H. Smith (H.); K.E. Sullivan (Kathleen); P. Szabolcs (Paul); A.J. Thrasher (Adrian); D. Torgerson; P. Veys (Paul); K. Weinberg (Kenneth); J.C. Zuniga-Pflucker (Juan Carlos)

    2014-01-01

    textabstractThe Primary Immune Deficiency Treatment Consortium (PIDTC) is a network of 33 centers in North America that study the treatment of rare and severe primary immunodeficiency diseases. Current protocols address the natural history of patients treated for severe combined immunodeficiency (SC

  19. Microbial Degradation of Aniline by Bacterial Consortium

    Institute of Scientific and Technical Information of China (English)

    JIAN-LONG WANG; ZE-YU MAO; WEI-ZHONG WU

    2003-01-01

    Objective To investigate the characteristics of microbial degradation of aniline by a stable bacterial consortium. Methods The bacterial consortium was isolated from activated sludge treating chemical wastewater using aniline as the sole source of carbon and nitrogen by enrichment and isolation technique. The biomass was measured as optical density (OD) at 510 nm using a spectrophotometer. Aniline concentrations were determined by spectrophotometer. The intermediates of aniline degradation were identified by GC/MS method. Results The bacterial consortium could grow at a range of aniline concentrations between 50 and 500 mg/L. The optimal pH and temperature for aniline degradation were determined to be 7.0 and 30, respectively. The presence of NH4NO3 as an additional nitrogen source (100-500 mg/L) had no adverse effect on bacterial growth and aniline degradation. The presence of heavy metal ions, such as Co2+, Zn2+, Ni2+, Mn2+ and Cu2+ had an inhibitory effect on aniline degradation. Conclusions The isolated bacterial consortium candegrade aniline up to 500 mg/L effectively and tolerate some heavy metal ions that commonly exist in chemical wastewater. It has a potential to be applied in the practical treatment of aniline-containingwastewater.

  20. Midwest Nuclear Science and Engineering Consortium

    International Nuclear Information System (INIS)

    The objective of the Midwest Nuclear Science and Engineering Consortium (MNSEC) is to enhance the scope, quality and integration of educational and research capabilities of nuclear sciences and engineering (NS/E) programs at partner schools in support of the U.S. nuclear industry (including DOE laboratories). With INIE support, MNSEC had a productive seven years and made impressive progress in achieving these goals. Since the past three years have been no-cost-extension periods, limited -- but notable -- progress has been made in FY10. Existing programs continue to be strengthened and broadened at Consortium partner institutions. The enthusiasm generated by the academic, state, federal, and industrial communities for the MNSEC activities is reflected in the significant leveraging that has occurred for our programs.

  1. Midwest Nuclear Science and Engineering Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Wynn Volkert; Dr. Arvind Kumar; Dr. Bryan Becker; Dr. Victor Schwinke; Dr. Angel Gonzalez; Dr. DOuglas McGregor

    2010-12-08

    The objective of the Midwest Nuclear Science and Engineering Consortium (MNSEC) is to enhance the scope, quality and integration of educational and research capabilities of nuclear sciences and engineering (NS/E) programs at partner schools in support of the U.S. nuclear industry (including DOE laboratories). With INIE support, MNSEC had a productive seven years and made impressive progress in achieving these goals. Since the past three years have been no-cost-extension periods, limited -- but notable -- progress has been made in FY10. Existing programs continue to be strengthened and broadened at Consortium partner institutions. The enthusiasm generated by the academic, state, federal, and industrial communities for the MNSEC activities is reflected in the significant leveraging that has occurred for our programs.

  2. Removal of triphenylmethane dyes by bacterial consortium.

    Science.gov (United States)

    Cheriaa, Jihane; Khaireddine, Monia; Rouabhia, Mahmoud; Bakhrouf, Amina

    2012-01-01

    A new consortium of four bacterial isolates (Agrobacterium radiobacter; Bacillus spp.; Sphingomonas paucimobilis, and Aeromonas hydrophila)-(CM-4) was used to degrade and to decolorize triphenylmethane dyes. All bacteria were isolated from activated sludge extracted from a wastewater treatment station of a dyeing industry plant. Individual bacterial isolates exhibited a remarkable color-removal capability against crystal violet (50 mg/L) and malachite green (50 mg/L) dyes within 24 h. Interestingly, the microbial consortium CM-4 shows a high decolorizing percentage for crystal violet and malachite green, respectively, 91% and 99% within 2 h. The rate of chemical oxygen demand (COD) removal increases after 24 h, reaching 61.5% and 84.2% for crystal violet and malachite green, respectively. UV-Visible absorption spectra, FTIR analysis and the inspection of bacterial cells growth indicated that color removal by the CM-4 was due to biodegradation. Evaluation of mutagenicity by using Salmonella typhimurium test strains, TA98 and TA100 studies revealed that the degradation of crystal violet and malachite green by CM-4 did not lead to mutagenic products. Altogether, these results demonstrated the usefulness of the bacterial consortium in the treatment of the textile dyes.

  3. Midwest superconductivity consortium. 1993 Progress report

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    The Midwest Superconductivity Consortium, MISCON, in the fourth year of operations further strengthened its mission to advance the science and understanding of high T{sub c} superconductivity. The goals of the organization and the individual projects continue to reflect the current needs for new knowledge in the field and the unique capabilities of the institutions involved. Group efforts and cooperative laboratory interactions to achieve the greatest possible synergy under the Consortium continue to be emphasized. Industrial affiliations coupled with technology transfer initiatives were expanded. Activities of the participants during the past year achieved an interactive and high level of performance. The number of notable achievements in the field contributed by Consortium investigators increased. The programmatic research continues to focus upon key materials-related problems in two areas. The first area has a focus upon {open_quotes}Synthesis and Processing{close_quotes} while the second is centered around {open_quotes}Limiting Features in Transport Properties of High T{sub c} Materials{close_quotes}.

  4. Removal of Triphenylmethane Dyes by Bacterial Consortium

    Directory of Open Access Journals (Sweden)

    Jihane Cheriaa

    2012-01-01

    Full Text Available A new consortium of four bacterial isolates (Agrobacterium radiobacter; Bacillus spp.; Sphingomonas paucimobilis, and Aeromonas hydrophila-(CM-4 was used to degrade and to decolorize triphenylmethane dyes. All bacteria were isolated from activated sludge extracted from a wastewater treatment station of a dyeing industry plant. Individual bacterial isolates exhibited a remarkable color-removal capability against crystal violet (50 mg/L and malachite green (50 mg/L dyes within 24 h. Interestingly, the microbial consortium CM-4 shows a high decolorizing percentage for crystal violet and malachite green, respectively, 91% and 99% within 2 h. The rate of chemical oxygen demand (COD removal increases after 24 h, reaching 61.5% and 84.2% for crystal violet and malachite green, respectively. UV-Visible absorption spectra, FTIR analysis and the inspection of bacterial cells growth indicated that color removal by the CM-4 was due to biodegradation. Evaluation of mutagenicity by using Salmonella typhimurium test strains, TA98 and TA100 studies revealed that the degradation of crystal violet and malachite green by CM-4 did not lead to mutagenic products. Altogether, these results demonstrated the usefulness of the bacterial consortium in the treatment of the textile dyes.

  5. CFD Parametric Study of Consortium Impeller

    Science.gov (United States)

    Cheng, Gary C.; Chen, Y. S.; Garcia, Roberto; Williams, Robert W.

    1993-01-01

    Current design of high performance turbopumps for rocket engines requires effective and robust analytical tools to provide design impact in a productive manner. The main goal of this study is to develop a robust and effective computational fluid dynamics (CFD) pump model for general turbopump design and analysis applications. A Finite Difference Navier-Stokes flow solver, FDNS, which includes the extended k-epsilon turbulence model and appropriate moving interface boundary conditions, was developed to analyze turbulent flows in turbomachinery devices. A second-order central difference scheme plus adaptive dissipation terms was employed in the FDNS code, along with a predictor plus multi-corrector pressure-based solution procedure. The multi-zone, multi-block capability allows the FDNS code to efficiently solve flow fields with complicated geometry. The FDNS code has been benchmarked by analyzing the pump consortium inducer, and it provided satisfactory results. In the present study, a CFD parametric study of the pump consortium impeller was conducted using the FDNS code. The pump consortium impeller, with partial blades, is a new design concept of the advanced rocket engines. The parametric study was to analyze the baseline design of the consortium impeller and its modification which utilizes TANDEM blades. In the present study, the TANDEM blade configuration of the consortium impeller considers cut full blades for about one quarter chord length from the leading edge and clocks the leading edge portion with an angle of 7.5 or 22.5 degrees. The purpose of the present study is to investigate the effect and trend of the TANDEM blade modification and provide the result as a design guideline. A 3-D flow analysis, with a 103 x 23 x 30 mesh grid system and with the inlet flow conditions measured by Rocketdyne, was performed for the baseline consortium impeller. The numerical result shows that the mass flow rate splits through various blade passages are relatively uniform

  6. Latest Developments of the Isprs Student Consortium

    Science.gov (United States)

    Detchev, I.; Kanjir, U.; Reyes, S. R.; Miyazaki, H.; Aktas, A. F.

    2016-06-01

    The International Society for Photogrammetry and Remote Sensing (ISPRS) Student Consortium (SC) is a network for young professionals studying or working within the fields of photogrammetry, remote sensing, Geographical Information Systems (GIS), and other related geo-spatial sciences. The main goal of the network is to provide means for information exchange for its young members and thus help promote and integrate youth into the ISPRS. Over the past four years the Student Consortium has successfully continued to fulfil its mission in both formal and informal ways. The formal means of communication of the SC are its website, newsletter, e-mail announcements and summer schools, while its informal ones are multiple social media outlets and various social activities during student related events. The newsletter is published every three to four months and provides both technical and experiential content relevant for the young people in the ISPRS. The SC has been in charge or at least has helped with organizing one or more summer schools every year. The organization's e-mail list has over 1,100 subscribers, its website hosts over 1,300 members from 100 countries across the entire globe, and its public Facebook group currently has over 4,500 joined visitors, who connect among one another and share information relevant for their professional careers. These numbers show that the Student Consortium has grown into a significant online-united community. The paper will present the organization's on-going and past activities for the last four years, its current priorities and a strategic plan and aspirations for the future four-year period.

  7. Midwest Superconductivity Consortium: 1994 Progress report

    International Nuclear Information System (INIS)

    The mission of the Midwest Superconductivity Consortium, MISCON, is to advance the science and understanding of high Tc superconductivity. During the past year, 27 projects produced over 123 talks and 139 publications. Group activities and interactions involved 2 MISCON group meetings (held in August and January); with the second MISCON Workshop held in August; 13 external speakers; 79 collaborations (with universities, industry, Federal laboratories, and foreign research centers); and 48 exchanges of samples and/or measurements. Research achievements this past year focused on understanding the effects of processing phenomena on structure-property interrelationships and the fundamental nature of transport properties in high-temperature superconductors

  8. University Research Consortium annual review meeting program

    International Nuclear Information System (INIS)

    This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators

  9. University Research Consortium annual review meeting program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    This brochure presents the program for the first annual review meeting of the University Research Consortium (URC) of the Idaho National Engineering Laboratory (INEL). INEL is a multiprogram laboratory with a distinctive role in applied engineering. It also conducts basic science research and development, and complex facility operations. The URC program consists of a portfolio of research projects funded by INEL and conducted at universities in the United States. In this program, summaries and participant lists for each project are presented as received from the principal investigators.

  10. `Research and Development of Technology for Controlling the Structure of Multiple-Function Component,` local research and development of important technology for fiscal 1997. 2. Technological development of advanced surface treatment for methane-powered aircraft engine components (Laser-aided advanced treatment system (technology)); 1997 nendo juyo chiiki gijutsu kenkyu kaihatsu `fukugo kino buzai kozo seigyo gijutsu no kenkyu kaihatsu`. 2. Methane nenryo kokukiyo engine buzai no kodo hyomen kako gijutsu kaihatsu (laser oyo senshin kako system gijutsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Surface reforming technologies, such as laser-aided Ti alloying, are studied for developing erosion-resistant materials for the fore section of a methane-fueled aircraft engine. In the formation of intermetallic compound film, the laser plasma hybrid spraying is applied for the formation of a film which is 100-400 times higher than Ti6Al4V in terms of resistance to erosion. For the quantitative evaluation of bond strength, a boundary shear testing jig is built. When the laser irradiating conditions are optimized, the boundary shear strength is elevated to 150-230MPa. NiAl film is studied for realizing resistance to high-temperature oxidation, and then a perfect NiAl film is obtained, which is done by use of a mechanical alloying powder mixed on the atomic level. In the manufacture of ceramic cermet film, a powder is studied, in which powder SiC and Al2O3, excellent in high-temperature oxidation characteristics and fracture toughness, are the parent materials which are coated by NiCr. It is found that an excellent oxidation-resistant film will be manufactured by use of this powder. 40 refs., 132 figs., 12 tabs.

  11. FY 1993 report of the results of the R and D of the important regional technology - Laser application advanced processing system technology. II. R and D of the composite functional member structure control technology (Development of the high grade surface processing technology of methane fueled aircraft use engine members); 1993 nendo juyo chiiki gijutsu kenkyu kaihtsu (fukugo kino buzai kozo seigyo gijutsu no kenkyu kaihatsu (methane nenryo kokukiyo engine buzai no kodo hyomen kako gijutsu kaihatsu). 2. Laser oyo senshin kako system gijutsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    In the fields of aerospace, energy, etc., the development is expected of materials for engine members which are reliable and durable for a long time under the severe environment. Materials are developed which are erosion-resistant under the non-erosion environment of the front of engine of methane fueled aircraft. The basic experiment was commenced on the fabrication of micro-fine surface of Ti-6Al-4V alloys, etc. by superimposed laser beam irradiation. As a technology to fabricate the composite surface layer by supplying alloy components on the material surface, the development was started of a technology to form hard coating by irradiating laser to the Ti alloy surface put with metal elements and compounds on. Literature survey was made of the laser surface reforming technology of Ti alloys, etc. using JOIS. As to the fabrication of the composite surface layer, it was found out that the layer is easy to be brittle together with hardness. In the experiment on the micro-fine surface fabrication, it was found out that as a characteristic of light collector, the integration mirror is flat in strength distribution. Concerning the fabrication of the composite surface layer, it is a must to make it gradient because micro cracks are generated with the rising surface hardness. (NEDO)

  12. Primary Immune Deficiency Treatment Consortium (PIDTC) update.

    Science.gov (United States)

    Griffith, Linda M; Cowan, Morton J; Notarangelo, Luigi D; Kohn, Donald B; Puck, Jennifer M; Shearer, William T; Burroughs, Lauri M; Torgerson, Troy R; Decaluwe, Hélène; Haddad, Elie

    2016-08-01

    The Primary Immune Deficiency Treatment Consortium (PIDTC) is a collaboration of 41 North American centers studying therapy for rare primary immune deficiency diseases (PIDs), including severe combined immune deficiency (SCID), Wiskott-Aldrich syndrome (WAS), and chronic granulomatous disease (CGD). An additional 3 European centers have partnered with the PIDTC to study CGD. Natural history protocols of the PIDTC analyze outcomes of treatment for rare PIDs in multicenter longitudinal retrospective, prospective, and cross-sectional studies. Since 2009, participating centers have enrolled more than 800 subjects on PIDTC protocols for SCID, and enrollment in the studies on WAS and CGD is underway. Four pilot projects have been funded, and 12 junior investigators have received fellowship awards. Important publications of the consortium describe the outcomes of hematopoietic cell transplantation for SCID during 2000-2009, diagnostic criteria for SCID, and the pilot project of newborn screening for SCID in the Navajo Nation. The PIDTC Annual Scientific Workshops provide an opportunity to strengthen collaborations with junior investigators, patient advocacy groups, and international colleagues. Funded by the National Institute of Allergy and Infectious Diseases and the Office of Rare Diseases Research, National Center for Advancing Translational Sciences, the PIDTC has recently received renewal for another 5 years. Here we review accomplishments of the group, projects underway, highlights of recent workshops, and challenges for the future. PMID:27262745

  13. Fermentative hydrogen production by microbial consortium

    Energy Technology Data Exchange (ETDEWEB)

    Maintinguer, Sandra I.; Fernandes, Bruna S.; Duarte, Iolanda C.S.; Saavedra, Nora Katia; Adorno, M. Angela T.; Varesche, M. Bernadete [Department of Hydraulics and Sanitation, School of Engineering of Sao Carlos, University of Sao Paulo, Av. Trabalhador Sao-carlense, 400, 13566-590 Sao Carlos-SP (Brazil)

    2008-08-15

    Heat pre-treatment of the inoculum associated to the pH control was applied to select hydrogen-producing bacteria and endospores-forming bacteria. The source of inoculum to the heat pre-treatment was from a UASB reactor used in the slaughterhouse waste treatment. The molecular biology analyses indicated that the microbial consortium presented microorganisms affiliated with Enterobacter cloacae (97% and 98%), Clostridium sp. (98%) and Clostridium acetobutyricum (96%), recognized as H{sub 2} and volatile acids' producers. The following assays were carried out in batch reactors in order to verify the efficiencies of sucrose conversion to H{sub 2} by the microbial consortium: (1) 630.0 mg sucrose/L, (2) 1184.0 mg sucrose/L, (3) 1816.0 mg sucrose/L and (4) 4128.0 mg sucrose/L. The subsequent yields were obtained as follows: 15% (1.2 mol H{sub 2}/mol sucrose), 20% (1.6 mol H{sub 2}/mol sucrose), 15% (1.2 mol H{sub 2}/mol sucrose) and 4% (0.3 mol H{sub 2}/mol sucrose), respectively. The intermediary products were acetic acid, butyric acid, methanol and ethanol in all of the anaerobic reactors. (author)

  14. BIODEGRADATION OF MTBE BY A MICROORGANISM CONSORTIUM

    Directory of Open Access Journals (Sweden)

    M. Alimohammadi, A. R. Mesdaghinia, M. Mahmoodi, S. Nasseri, A. H. Mahvi and J. Nouri

    2005-10-01

    Full Text Available Methyl Tert-Butyl Ether (MTBE is one of the ether oxygenates which its use has been increased within the last twenty years. This compound is produced from isobutylene and methanol reaction that is used as octane index enhancer and also increases dissolved oxygen in gasoline and decreases carbon monoxide emission in four phased motors because of better combustion of gasoline. High solubility in water (52 g/L, high vapor pressure (0.54 kg/cm3, low absorption to organic carbon of soil and presence of MTBE in the list of potentially-carcinogens of U.S EPA has made its use of great concern. The culture media used in this study was Mineral Salt Medium (MSM. The study lasted for 236 days and in three different concentrations of MTBE of 200, 5 and 0.8 mg/L. A control sample was also used to compare the results. This research studied the isolation methods of microbial consortium in the MTBE polluted soils in Tehran and Abadan petroleum refinery besides MTBE degradation. The results showed the capability of bacteria in consuming MTBE as carbon source. Final microbial isolation was performed with several microbial passages as well as keeping consortium in a certain amount of MTBE as the carbon source.

  15. The NIH Extracellular RNA Communication Consortium

    Directory of Open Access Journals (Sweden)

    Alexandra M. Ainsztein

    2015-08-01

    Full Text Available The Extracellular RNA (exRNA Communication Consortium, funded as an initiative of the NIH Common Fund, represents a consortium of investigators assembled to address the critical issues in the exRNA research arena. The overarching goal is to generate a multi-component community resource for sharing fundamental scientific discoveries, protocols, and innovative tools and technologies. The key initiatives include (a generating a reference catalogue of exRNAs present in body fluids of normal healthy individuals that would facilitate disease diagnosis and therapies, (b defining the fundamental principles of exRNA biogenesis, distribution, uptake, and function, as well as development of molecular tools, technologies, and imaging modalities to enable these studies, (c identifying exRNA biomarkers of disease, (d demonstrating clinical utility of exRNAs as therapeutic agents and developing scalable technologies required for these studies, and (e developing a community resource, the exRNA Atlas, to provide the scientific community access to exRNA data, standardized exRNA protocols, and other useful tools and technologies generated by funded investigators.

  16. Consortium for Petroleum & Natural Gas Stripper Wells

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison; Sharon L. Elder

    2006-09-30

    The Pennsylvania State University, under contract to the U.S. Department of Energy (DOE), National Energy Technology Laboratory (NETL) established a national industry-driven Stripper Well Consortium (SWC) that is focused on improving the production performance of domestic petroleum and/or natural gas stripper wells. The consortium creates a partnership with the U.S. petroleum and natural gas producers, trade associations, state funding agencies, academia, and the National Energy Technology Laboratory. This report serves as the tenth quarterly technical progress report for the SWC. Key activities for this reporting period include: {lg_bullet} 2004 SWC Final Project Reports distribution; {lg_bullet} Exhibit and present at the Midcontinent Oil and Gas Prospect Fair, Great Bend, KS, September 12, 2006; {lg_bullet} Participate and showcase current and past projects at the 2006 Oklahoma Oil and Gas Trade Expo, Oklahoma City, OK, October 26, 2006; {lg_bullet} Finalize agenda and identify exhibitors for the northeastern US, Fall SWC Technical Transfer Workshop, Pittsburghhh, PA, November 9, 2006; {lg_bullet} Continue distribution of the public broadcast documentary, ''Independent Oil: Rediscovering American's Forgotten Wells''; {lg_bullet} Communications/outreach; and {lg_bullet} New members update.

  17. Overview of the carbon products consortium (CPC)

    Energy Technology Data Exchange (ETDEWEB)

    Irwin, C.L. [West Virginia Univ., Morgantown, WV (United States)

    1996-08-01

    The Carbon Products Consortium (CPC) is an industry, university, government cooperative research team which has evolved over the past seven years to produce and evaluate coal-derived feedstocks for carbon products. The members of the Carbon Products Consortium are UCAR Carbon Company, Koppers Industries, CONOCO, Aluminum Company of America, AMOCO Polymers, and West Virginia University. The Carbon and Insulation Materials Technology Group at Oak Ridge National Laboratory, Fiber Materials Inc., and BASF Corporation are affiliates of the CPC. The initial work on coal-derived nuclear graphites was supported by a grant to WVU, UCAR Carbon, and ORNL from the U.S. DOE New Production Reactor program. More recently, the CPC program has been supported through the Fossil Energy Materials program and through PETC`s Liquefaction program. The coal processing technologies involve hydrogenation, extraction by solvents such as N-methyl pyrolidone and toluene, material blending, and calcination. The breadth of carbon science expertise and manufacturing capability available in the CPC enables it to address virtually all research and development issues of importance to the carbon products industry.

  18. The Financing of the Michigan Library Consortium. Paper No. 3.

    Science.gov (United States)

    Michigan Library Consortium, Detroit.

    Since the formal organization of the Michigan Library Consortium, its financial support has come through membership fees and a grant from the Michigan State Library from Title III funds. The financing of the consortium is already a complex operation and will become even more complex as new programs are undertaken, since funds have been accepted…

  19. The Consortium for Higher Education Tax Reform Report

    Science.gov (United States)

    Center for Postsecondary and Economic Success, 2014

    2014-01-01

    This White Paper presents the work of the Consortium for Higher Education Tax Reform, a partnership funded by the Bill & Melinda Gates Foundation as part of the second phase of its Reimagining Aid Design and Delivery (RADD) initiative. Consortium partners are the Center for Postsecondary and Economic Success at CLASP, the Education Trust, New…

  20. Urban Consortium Energy Task Force - Year 21 Final Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-04-01

    The Urban Consortium Energy Task Force (UCETF), comprised of representatives of large cities and counties in the United States, is a subgroup of the Urban Consortium, an organization of the nation's largest cities and counties joined together to identify, develop and deploy innovative approaches and technological solutions to pressing urban issues.

  1. The Black Rock Forest Consortium: A narrative

    Science.gov (United States)

    Buzzetto-More, Nicole Antoinette

    The Black Rock Forest is a 3,785-acre wilderness area whose richly forested landscape represents the splendor of the Hudson Valley Region of New York State. Although originally intended to become the home of wealthy banker James Stillman, it was his son Ernest whose love of conservation caused him to embrace the then new and revolutionary practice of sustainable forestry and establish Black Rock in 1928. Due to Ernest Stillman's foresight, the property was protected from development and bequeathed to Harvard University following his death for the establishment of an experimental forest. The modern environmental movement in America began when the Black Rock Forest was threatened with development by Consolidated Edison, and the people of the surrounding community banded together, battling tirelessly for over 17 years to stop the degradation of this historic forest. The outcome of this crusade marked a hallmark win for the environment leaving an illustrious and inveterate legacy. The campaign resulted in the watershed legislation the National Environmental Policy Act, the formation of several environmental advocacy groups, the creation of the Council on Environmental Quality of the Executive Office of the President, as well as set a precedent for communities to initiate and win cases against major corporations in order to safeguard natural resources. In the midst of the controversy it became apparent that alternative futures for the Forest needed to be explored. As a result of a committee report and one man's vision, the idea emerged to create a consortium that would purchase and steward the Forest. With a formation that took nearly fifteen years, the Black Rock Forest Consortium was formed, a unique amalgamation of K--12 public and private schools, colleges and universities, and science and cultural centers that successfully collaborate to enhance scientific research, environmental conservation, and education. The Consortium works to bridge the gaps between learners

  2. The virtual atomic and molecular data centre (VAMDC) consortium

    Science.gov (United States)

    Dubernet, M. L.; Antony, B. K.; Ba, Y. A.; Babikov, Yu L.; Bartschat, K.; Boudon, V.; Braams, B. J.; Chung, H.-K.; Daniel, F.; Delahaye, F.; Del Zanna, G.; de Urquijo, J.; Dimitrijević, M. S.; Domaracka, A.; Doronin, M.; Drouin, B. J.; Endres, C. P.; Fazliev, A. Z.; Gagarin, S. V.; Gordon, I. E.; Gratier, P.; Heiter, U.; Hill, C.; Jevremović, D.; Joblin, C.; Kasprzak, A.; Krishnakumar, E.; Leto, G.; Loboda, P. A.; Louge, T.; Maclot, S.; Marinković, B. P.; Markwick, A.; Marquart, T.; Mason, H. E.; Mason, N. J.; Mendoza, C.; Mihajlov, A. A.; Millar, T. J.; Moreau, N.; Mulas, G.; Pakhomov, Yu; Palmeri, P.; Pancheshnyi, S.; Perevalov, V. I.; Piskunov, N.; Postler, J.; Quinet, P.; Quintas-Sánchez, E.; Ralchenko, Yu; Rhee, Y.-J.; Rixon, G.; Rothman, L. S.; Roueff, E.; Ryabchikova, T.; Sahal-Bréchot, S.; Scheier, P.; Schlemmer, S.; Schmitt, B.; Stempels, E.; Tashkun, S.; Tennyson, J.; Tyuterev, Vl G.; Vujčić, V.; Wakelam, V.; Walton, N. A.; Zatsarinny, O.; Zeippen, C. J.; Zwölf, C. M.

    2016-04-01

    The Virtual Atomic and Molecular Data Centre (VAMDC) Consortium is a worldwide consortium which federates atomic and molecular databases through an e-science infrastructure and an organisation to support this activity. About 90% of the inter-connected databases handle data that are used for the interpretation of astronomical spectra and for modelling in many fields of astrophysics. Recently the VAMDC Consortium has connected databases from the radiation damage and the plasma communities, as well as promoting the publication of data from Indian institutes. This paper describes how the VAMDC Consortium is organised for the optimal distribution of atomic and molecular data for scientific research. It is noted that the VAMDC Consortium strongly advocates that authors of research papers using data cite the original experimental and theoretical papers as well as the relevant databases. .

  3. Midwest Superconductivity Consortium. Progress report, 1992

    Energy Technology Data Exchange (ETDEWEB)

    Bement, A.L. Jr.

    1993-01-01

    Mission of the Midwest Superconductivity Consortium, MISCON, is to advance the science and understanding of high Tc superconductivity. Programmatic research focuses upon key materials-related problems; principally, synthesis and processing and properties limiting transport phenomena. During the past year, 26 projects produced over 133 talks and 113 publications. publications. Two Master`s Degrees and one Ph.D. were granted to students working on MISCON projects. Group activities and interactions involved two MISCON group meetings (held in July and January), twenty external speakers, 36 collaborations, 10 exchanges of samples and/or measurements, and one (1) gift of equipment from industry. Research achievements this past year expanded our understanding of processing phenomena on structure property interrelationships and the fundamental nature of transport properties in high-temperature superconductors.

  4. Consortium sandbox: building and sharing resources.

    Science.gov (United States)

    Lim, Mark D

    2014-06-25

    Some common challenges of biomedical product translation-scientific, regulatory, adoption, and reimbursement-can best be addressed by the broad sharing of resources or tools. But, such aids remain undeveloped because the undertaking requires expertise from multiple research sectors as well as validation across organizations. Biomedical resource development can benefit from directed consortia-a partnership framework that provides neutral and temporary collaborative environments for several, oftentimes competing, organizations and leverages the aggregated intellect and resources of stakeholders so as to create versatile solutions. By analyzing 369 biomedical research consortia, we tracked consortia growth around the world and gained insight into how this partnership model advances biomedical research. Our analyses suggest that research-by-consortium provides benefit to biomedical science, but the model needs further optimization before it can be fully integrated into the biomedical research pipeline.

  5. Fiscal 2000 project of inviting proposals for international joint research - invitation for international proposal (Energy conservation No.4). Development of passive cooling mechanism fit for high-temperature high-humidity region; 2000 nendo kokusai kyodo kenkyu teian kobo jigyo - kokusai teian kobo (Shoe No.4). Koon tashitsu chiiki tekigogata passive reikyaku kiko no kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Efforts are made in cooperation with Vietnam to develop a heat insulating material for buildings, to be used for passive cooling mechanisms symbiotic with the environment and capable of energy conservation. Vegetables are planted on the surface of this building material. Activities are conducted in the three domains of (1) the development of energy conservation-conscious basic materials, (2) selection of vegetables, and (3) the simulation of the effect of the developed materials on temperature. The basic type of the newly developed building material is an asbestos-free vegetable fiber-reinforced cement slate which is covered by such vegetables as members of the Passifloraceae, Vitaceae, and Araliaceae. Conducted in domain (1) are surveys of the actual state of basic material manufacturing in Vietnam and studies of the basic properties of vegetable fiber, properties displayed by vegetable fiber under various chemical environments, selection of vegetable fiber as the basic aggregate, mineral fiber, and the basic material manufacturing conditions. The result of heat load calculation carried out using SMASH for Windows ver.2, which is a program developed for thermal load calculation for houses, shows that the new material lowers the temperature by approximately 3 degrees C. (NEDO)

  6. `Technology for Advanced Treatment of High Melting Point Metal-Based Material,` local research and development of important technology for fiscal 1997. Development of materials creation technology for high efficiency power generator components; 1997 nendo juyo chiiki gijutsu kenkyu kaihatsu. `Koyuten kinzokukei buzai no kodo kako gijutsu` (kokoritsu hatsuden`yo buzai sosei gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Efforts are made for the creation of high melting point metal-base materials to replace the currently-used Ni-base superalloys for the turbine to withstand higher operating temperatures. The main efforts made in fiscal 1997 are outlined. As in fiscal 1996, Nb-base solution alloys, in which solution reinforcement elements such as Mo and W are alloyed, are manufactured by button arc melting and tested for mechanical properties and texture/characteristics. In the designing and evaluation for a strongest Nb-base composite material, Nb-base composite materials are manufactured by use of particle dispersion-strengthening attained by addition of intermetallic compounds or elements to contribute to the formation of oxides, carbides, or nitrides. Nb-base composite materials may also be manufactured by use of eutectic-strengthening attained by utilizing crystallization in the process of coagulation. The resultant Nb-base composite materials are evaluated for their dynamic characteristics at high temperatures. In the development and evaluation of technologies for creating Nb-base materials for high-temperature components, larger specimens as heavy as several kg are tested in line with small specimens for basic studies, and the results are utilized for alloy designing for high-temperature materials. 50 refs., 97 figs., 15 tabs.

  7. SEEA SOUTHEAST CONSORTIUM FINAL TECHNICAL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Block, Timothy [Southeast Energy Efficiency Alliance; Ball, Kia [Southeast Energy Efficiency Alliance; Fournier, Ashley [Southeast Energy Efficiency Alliance

    2014-01-21

    In 2010 the Southeast Energy Efficiency Alliance (SEEA) received a $20 million Energy Efficiency and Conservation Block Grant (EECBG) under the U.S. Department of Energy’s Better Building Neighborhood Program (BBNP). This grant, funded by the American Recovery and Reinvestment Act, also included sub-grantees in 13 communities across the Southeast, known as the Southeast Consortium. The objective of this project was to establish a framework for energy efficiency retrofit programs to create models for replication across the Southeast and beyond. To achieve this goal, SEEA and its project partners focused on establishing infrastructure to develop and sustain the energy efficiency market in specific localities across the southeast. Activities included implementing minimum training standards and credentials for marketplace suppliers, educating and engaging homeowners on the benefits of energy efficiency through strategic marketing and outreach and addressing real or perceived financial barriers to investments in whole-home energy efficiency through a variety of financing mechanisms. The anticipated outcome of these activities would be best practice models for program design, marketing, financing, data collection and evaluation as well as increased market demand for energy efficiency retrofits and products. The Southeast Consortium’s programmatic impacts along with the impacts of the other BBNP grantees would further the progress towards the overall goal of energy efficiency market transformation. As the primary grantee SEEA served as the overall program administrator and provided common resources to the 13 Southeast Consortium sub-grantees including contracted services for contractor training, quality assurance testing, data collection, reporting and compliance. Sub-grantee programs were located in cities across eight states including Alabama, Florida, Georgia, Louisiana, North Carolina, South Carolina, Tennessee, Virginia and the U.S. Virgin Islands. Each sub

  8. Establishing an International Soil Modelling Consortium

    Science.gov (United States)

    Vereecken, Harry; Schnepf, Andrea; Vanderborght, Jan

    2015-04-01

    -change-feedback processes, bridge basic soil science research and management, and facilitate the communication between science and society . To meet these challenges an international community effort is required, similar to initiatives in systems biology, hydrology, and climate and crop research. We therefore propose to establish an international soil modelling consortium with the aims of 1) bringing together leading experts in modelling soil processes within all major soil disciplines, 2) addressing major scientific gaps in describing key processes and their long term impacts with respect to the different functions and ecosystem services provided by soil, 3) intercomparing soil model performance based on standardized and harmonized data sets, 4) identifying interactions with other relevant platforms related to common data formats, protocols and ontologies, 5) developing new approaches to inverse modelling, calibration, and validation of soil models, 6) integrating soil modelling expertise and state of the art knowledge on soil processes in climate, land surface, ecological, crop and contaminant models, and 7) linking process models with new observation, measurement and data evaluation technologies for mapping and characterizing soil properties across scales. Our consortium will bring together modelers and experimental soil scientists at the forefront of new technologies and approaches to characterize soils. By addressing these aims, the consortium will contribute to improve the role of soil modeling as a knowledge dissemination instrument in addressing key global issues and stimulate the development of translational research activities. This presentation will provide a compelling case for this much-needed effort, with a focus on tangible benefits to the scientific and food security communities.

  9. Consortium for Petroleum & Natural Gas Stripper Wells

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, Joel

    2011-12-01

    The United States has more oil and gas wells than any other country. As of December 31, 2004, there were more than half a million producing oil wells in the United States. That is more than three times the combined total for the next three leaders: China, Canada, and Russia. The Stripper Well Consortium (SWC) is a partnership that includes domestic oil and gas producers, service and supply companies, trade associations, academia, the Department of Energy’s Strategic Center for Natural Gas and Oil (SCNGO) at the National Energy Technology Laboratory (NETL), and the New York State Energy Research and Development Authority (NYSERDA). The Consortium was established in 2000. This report serves as a final technical report for the SWC activities conducted over the May 1, 2004 to December 1, 2011 timeframe. During this timeframe, the SWC worked with 173 members in 29 states and three international countries, to focus on the development of new technologies to benefit the U.S. stripper well industry. SWC worked with NETL to develop a nationwide request-for-proposal (RFP) process to solicit proposals from the U.S. stripper well industry to develop and/or deploy new technologies that would assist small producers in improving the production performance of their stripper well operations. SWC conducted eight rounds of funding. A total of 132 proposals were received. The proposals were compiled and distributed to an industry-driven SWC executive council and program sponsors for review. Applicants were required to make a formal technical presentation to the SWC membership, executive council, and program sponsors. After reviewing the proposals and listening to the presentations, the executive council made their funding recommendations to program sponsors. A total of 64 projects were selected for funding, of which 59 were fully completed. Penn State then worked with grant awardees to issue a subcontract for their approved work. SWC organized and hosted a total of 14 meetings

  10. Multi-University Southeast INIE Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Ayman Hawari; Nolan Hertel; Mohamed Al-Sheikhly; Laurence Miller; Abdel-Moeze Bayoumi; Ali Haghighat; Kenneth Lewis

    2010-12-29

    2 Project Summary: The Multi-University Southeast INIE Consortium (MUSIC) was established in response to the US Department of Energy’s (DOE) Innovations in Nuclear Infrastructure and Education (INIE) program. MUSIC was established as a consortium composed of academic members and national laboratory partners. The members of MUSIC are the nuclear engineering programs and research reactors of Georgia Institute of Technology (GIT), North Carolina State University (NCSU), University of Maryland (UMD), University of South Carolina (USC), and University of Tennessee (UTK). The University of Florida (UF), and South Carolina State University (SCSU) were added to the MUSIC membership in the second year. In addition, to ensure proper coordination between the academic community and the nation’s premier research and development centers in the fields of nuclear science and engineering, MUSIC created strategic partnerships with Oak Ridge National Laboratory (ORNL) including the Spallation Neutron Source (SNS) project and the Joint Institute for Neutron Scattering (JINS), and the National Institute of Standards and Technology (NIST). A partnership was also created with the Armed Forces Radiobiology Research Institute (AFRRI) with the aim of utilizing their reactor in research if funding becomes available. Consequently, there are three university research reactors (URRs) within MUSIC, which are located at NCSU (1-MW PULSTAR), UMD (0.25-MW TRIGA) and UF (0.10-MW Argonaut), and the AFRRI reactor (1-MW TRIGA MARK F). The overall objectives of MUSIC are: a) Demonstrate that University Research Reactors (URR) can be used as modern and innovative instruments of research in the basic and applied sciences, which include applications in fundamental physics, materials science and engineering, nondestructive examination, elemental analysis, and contributions to research in the health and medical sciences, b) Establish a strong technical collaboration between the nuclear engineering

  11. Multi-University Southeast INIE Consortium

    International Nuclear Information System (INIS)

    The Multi-University Southeast INIE Consortium (MUSIC) was established in response to the US Department of Energy's (DOE) Innovations in Nuclear Infrastructure and Education (INIE) program. MUSIC was established as a consortium composed of academic members and national laboratory partners. The members of MUSIC are the nuclear engineering programs and research reactors of Georgia Institute of Technology (GIT), North Carolina State University (NCSU), University of Maryland (UMD), University of South Carolina (USC), and University of Tennessee (UTK). The University of Florida (UF), and South Carolina State University (SCSU) were added to the MUSIC membership in the second year. In addition, to ensure proper coordination between the academic community and the nation's premier research and development centers in the fields of nuclear science and engineering, MUSIC created strategic partnerships with Oak Ridge National Laboratory (ORNL) including the Spallation Neutron Source (SNS) project and the Joint Institute for Neutron Scattering (JINS), and the National Institute of Standards and Technology (NIST). A partnership was also created with the Armed Forces Radiobiology Research Institute (AFRRI) with the aim of utilizing their reactor in research if funding becomes available. Consequently, there are three university research reactors (URRs) within MUSIC, which are located at NCSU (1-MW PULSTAR), UMD (0.25-MW TRIGA) and UF (0.10-MW Argonaut), and the AFRRI reactor (1-MW TRIGA MARK F). The overall objectives of MUSIC are: (a) Demonstrate that University Research Reactors (URR) can be used as modern and innovative instruments of research in the basic and applied sciences, which include applications in fundamental physics, materials science and engineering, nondestructive examination, elemental analysis, and contributions to research in the health and medical sciences, (b) Establish a strong technical collaboration between the nuclear engineering faculty and the MUSIC URRs

  12. Astroparticle Physics European Consortium Town Meeting Conference

    CERN Document Server

    2016-01-01

    The Astroparticle Physics European Consortium (APPEC) invites you to a town meeting at the Grand Amphithéatre de Sorbonne in Paris on the 6th and 7th April 2016 to discuss an update of the 2011 APPEC Astroparticle Physics roadmap, to be published in September 2016. In 2014 APPEC decided to launch an update of the 2011 Roadmap, transforming it to a “resource aware” roadmap. The intention was to gauge the financial impact of the beginnings of operation of the large global scale observatories put forward in the previous roadmap and to examine the possibilities of international coordination of future global initiatives. The APPEC Scientific Advisory Committee examined the field and prepared a set of recommendations. Based on these recommendations, the APPEC General Assembly drafted a set of “considerations” to be published by end of February 2016 and be debated in an open dialogue with the community, through the web page but primarily at the town meeting of 6-7 April. Based on this debate the final re...

  13. Epidemiology of Endometrial Cancer Consortium (E2C2)

    Science.gov (United States)

    The Epidemiology of Endometrial Cancer Consortium studies the etiology of this common cancer and build on resources from existing studies by combining data across studies in order to advance the understanding of the etiology of this disease.

  14. Men of African Descent and Carcinoma of the Prostate Consortium

    Science.gov (United States)

    The Men of African Descent and Carcinoma of the Prostate Consortium collaborates on epidemiologic studies to address the high burden of prostate cancer and to understand the causes of etiology and outcomes among men of African ancestry.

  15. Breast and Prostate Cancer Cohort Consortium (BPC3)

    Science.gov (United States)

    Breast and Prostate Cancer Cohort Consortium collaborates with three genomic facilities, epidemiologists, population geneticists, and biostatisticians from multiple institutions to study hormone-related gene variants and environmental factors in breast and prostate cancers.

  16. The nation's first consortium to address waste management issues

    International Nuclear Information System (INIS)

    On July 26, 1989, the secretary of the Department of Energy (DOE), Admiral James Watkins, announced approval of the Waste-Management Education and Research Consortium (WERC). The consortium is composed of New Mexico State University (NMSU), the University of New Mexico, the New Mexico Institute of Mining and Technology, Los Alamos National Laboratory, and Sandia National Laboratories. This pilot program is expected to form a model for other regional and national programs. The WERC mission is to expand the national capability to address issues associated with the management of hazardous, radioactive, and solid waste. Research, technology transfer, and education/training are the three areas that have been identified to accomplish the objectives set by the consortium. The members of the consortium will reach out to the DOE facilities, other government agencies and facilities, and private institutions across the country. Their goal is to provide resources for solutions to waste management problems

  17. Kinetics and characteristics of phenanthrene degradation by a microbial consortium

    Institute of Scientific and Technical Information of China (English)

    Wang Jin; Xu Hongke; An Mingquan; Yan Guiwen

    2008-01-01

    The kinetics and characteristics of phenanthrene degradation by a microbial consortium W4 isolated from Henan Oilfield were investigated. The degradation percentage of solid phenanthrene at 200 mg/L in liquid medium after 6 days of incubation was higher than 95% under the condition of 37 ℃ and 120 r/min by this microbial consortium. The degradation of phenanthrene could be fitted to a first-order kinetic model with the half-life of 1.25 days. The optimum conditions for degradation of phenanthrene by consortium W4 were as follows: temperature about 37 ℃, pH from 6.0 to 7.0 and salinity about 8.0 g/L.It was concluded that microbial consortium W4 might degrade phenanthrene via both salicylic acid and o-phthalic acid pathways by analyzing products with GC-MS.

  18. Biodeterioration studies of thermoplastics in nature using indigenous bacterial consortium

    Directory of Open Access Journals (Sweden)

    Mohd. Shahbaz Anwar

    2013-06-01

    Full Text Available Thermoplastics, poly vinyl chloride and low-density polyethylene were treated in the presence of indigenously developed bacterial consortium in laboratory and natural conditions. The consortium was developed using four bacteria, selected on the basis of utilization of PVC as primary carbon source, namely P. otitidis, B. aerius, B. cereus and A. pedis isolated from the plastic waste disposal sites in Northern India. The comparative in-vitro treatment studies as revealed by the spectral and thermal data, illustrated the relatively better biodegradation potential of developed consortium for PVC than the LDPE. Further, the progressive treatments of both the thermoplastics were conducted for three months under natural conditions. For this purpose, bioformulation of consortium was prepared and characterized for the viability up to 70 days of storage at 25±1ºC. The consortium treated polymer samples were monitored through SEM and FT-IR spectroscopy. Analytical data revealed the biodeterioration potential of the developed consortium for PVC and LDPE, which could help in disposing the plastic waste.

  19. Enrichment strategy to select functional consortium from mixed cultures: Consortium from rumen liquor for simultaneous cellulose degradation and hydrogen production

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Aijie; Ren, Nanqi [State Key Lab of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090 (China); School of Environmental and Municipal Engineering, Harbin Institute of Technology, Harbin 150090 (China); Gao, Lingfang; Xu, Jifei; Liu, Chong; Lee, Duu-Jong [School of Environmental and Municipal Engineering, Harbin Institute of Technology, Harbin 150090 (China)

    2010-12-15

    Strain isolation using conventional roll tube/plating technique is time consuming and is able to culture in vitro only a small fraction of existing microbes in a natural microflora. This paper proposed a simple and rapid method to select the as-simple-as-possible biological consortium by serially diluting the original mixed culture. The diluted which remains, while the one diluted in serial loses the target function, is defined as the functional consortium of the original mixed culture. Since the microbial structure and the reaction pathway incorporated with the functional consortium is much simpler than its original mother liquor, detailed analysis on the strain interaction is possible without the risk of losing key functional strains as often caused from conventional isolation method. The rumen liquor that can degrade cellulose and produce hydrogen is used as a demonstration example. A ''rumen cellulose-degrading bacterial consortium'' (RCBC) was identified using the proposed enrichment strategy. (author)

  20. Augmentation of a Microbial Consortium for Enhanced Polylactide (PLA) Degradation.

    Science.gov (United States)

    Nair, Nimisha R; Sekhar, Vini C; Nampoothiri, K Madhavan

    2016-03-01

    Bioplastics are eco-friendly and derived from renewable biomass sources. Innovation in recycling methods will tackle some of the critical issues facing the acceptance of bioplastics. Polylactic acid (PLA) is the commonly used and well-studied bioplastic that is presumed to be biodegradable. Considering their demand and use in near future, exploration for microbes capable of bioplastic degradation has high potential. Four PLA degrading strains were isolated and identified as Penicillium chrysogenum, Cladosporium sphaerospermum, Serratia marcescens and Rhodotorula mucilaginosa. A consortium of above strains degraded 44 % (w/w) PLA in 30 days time in laboratory conditions. Subsequently, the microbial consortium employed effectively for PLA composting. PMID:26843697

  1. 24 CFR 943.128 - How does a consortium carry out planning and reporting functions?

    Science.gov (United States)

    2010-04-01

    ... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING AGENCY CONSORTIA AND JOINT VENTURES... the consortium agreement, the consortium must submit joint five-year Plans and joint Annual Plans for... the joint PHA Plan....

  2. Computational Astrophysics Consortium 3 - Supernovae, Gamma-Ray Bursts and Nucleosynthesis

    Energy Technology Data Exchange (ETDEWEB)

    Woosley, Stan [Univ. of California, Santa Cruz, CA (United States)

    2014-08-29

    Final project report for UCSC's participation in the Computational Astrophysics Consortium - Supernovae, Gamma-Ray Bursts and Nucleosynthesis. As an appendix, the report of the entire Consortium is also appended.

  3. On the Consortium for Business Object Promotion (CBOP)

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    This paper deals with the goals and visions of a consortium inJapan, named Cons ortium for Business Object Promotion (CBOP), discussing its background, activiti es, and basic technical approaches to share and exchanging various types of Busi ness Objects. Especially, Object Pattern Technologies used in CBOP should be di scussed.

  4. NASA Consortium awards funding to Virginia Tech's geospatial program

    OpenAIRE

    Davis, Lynn

    2004-01-01

    NASA has selected a partnership between the Virginia Space Grant Consortium (VSGC) and Virginia Tech to receive a $100,000 grant for geospatial education and work force development. The grant, awarded through the NASA Space Grant College and Fellowship program, allows the partners to continue the already successful Virginia Geospatial Extension Program that was established in July 2003.

  5. The Worker Rights Consortium Makes Strides toward Legitimacy.

    Science.gov (United States)

    Van der Werf, Martin

    2000-01-01

    Discusses the rapid growth of the Workers Rights Consortium, a student-originated group with 44 member institutions which opposes sweatshop labor conditions especially in the apparel industry. Notes disagreements about the number of administrators on the board of directors and about the role of industry representives. Compares this group with the…

  6. It Takes a Consortium to Support Open Textbooks

    Science.gov (United States)

    Baker, Judy

    2009-01-01

    If the Community College Consortium for Open Educational Resources (CCCOER) has its way, expensive textbooks may go the way of typewriters and carbon paper. Ideally, Internet access for all students would allow educators to replace commercially printed textbooks with interactive digital textbooks and personal learning environments. However, until…

  7. The mammalian gene function resource: The International Knockout Mouse Consortium

    NARCIS (Netherlands)

    A. Bradley (Allan); K. Anastassiadis (Konstantinos); A. Ayadi (Abdelkader); J.F. Battey (James); C. Bell (Cindy); M.-C. Birling (Marie-Christine); J. Bottomley (Joanna); S.D.M. Brown (Steve); F. Bürger (Friederike); C.J. Bult (Carol); W. Bushell (Wendy); F.S. Collins (Francis); C. Desaintes (Christian); B. Doe (Brendan); E. Aris (Economides); J.T. Eppig (Janan); R.H. Finnell (Richard); C. Fletcher (Colin); M. Fray (Martin); D. Frendewey (David); R.H. Friedel (Roland); F.G. Grosveld (Frank); J. Hansen; Y. Hérault (Yann); G. Hicks (Geoffrey); A. Hörlein (Andreas); C. Houghton (Catherine); M. Hrabé De Angelis (Martin); D. Huylebroeck (Danny); V. Iyer (Vivek); P.J. de Jong (Pieter); J.A. Kadin (James); C. Kaloff (Cornelia); K. Kennedy (Karen); M. Koutsourakis (Manousos); K.C. Kent Lloyd (K.); S. Marschall (Susan); J. Mason (Jeremy); C. McKerlie (Colin); M.P. McLeod (Michael); H. von Melchner (Harald); M. Moore (Matt); A.O. Mujica (Alejandro); A. Nagy (Andras); M. Nefedov (Mikhail); L.M. Nutter (Lauryl); G. Pavlovic (Guillaume); J.L. Peterson (Jane); I. Pollock; R. Ramirez-Solis (Ramiro); D.E. Rancourt (Derrick); M. Raspa (Marcello); J.E. Remacle (Jacques); M. Ringwald (Martin); B. Rosen (Barry); N. Rosenthal (Nadia); J. Rossant (Janet); P. Ruiz Noppinger (Patricia); S. Ryder; J.Z. Schick (Joel Zupicich); F. Schnütgen (Frank); C.J. Schofield (Christopher); C. Seisenberger (Claudia); M. Selloum (Mohammed); E.M. Simpson (Elizabeth); W.C. Skarnes (William); D. Smedley (Damian); W.L. Stanford (William); A. Francis Stewart (A.); K. Stone (Kevin); K. Swan (Kate); H. Tadepally (Hamsa); J.L. Teboul (Jean Louis); G.P. Tocchini-Valentini (Glauco); D. Valenzuela (David); A.P. West (Anthony); K.-I. Yamamura (Ken-Ichi); Y. Yoshinaga (Yuko); M. Wurst (Martin)

    2012-01-01

    textabstractIn 2007, the International Knockout Mouse Consortium (IKMC) made the ambitious promise to generate mutations in virtually every protein-coding gene of the mouse genome in a concerted worldwide action. Now, 5 years later, the IKMC members have developed highthroughput gene trapping and, i

  8. The Consortium for Advancing Renewable Energy Technology (CARET)

    Science.gov (United States)

    Gordon, E. M.; Henderson, D. O.; Buffinger, D. R.; Fuller, C. W.; Uribe, R. M.

    1998-01-01

    The Consortium for Advancing Renewable Energy (CARET) is a research and education program which uses the theme of renewable energy to build a minority scientist pipeline. CARET is also a consortium of four universities and NASA Lewis Research Center working together to promote science education and research to minority students using the theme of renewable energy. The consortium membership includes the HBCUs (Historically Black Colleges and Universities), Fisk, Wilberforce and Central State Universities as well as Kent State University and NASA Lewis Research Center. The various stages of this pipeline provide participating students experiences with a different emphasis. Some emphasize building enthusiasm for the classroom study of science and technology while others emphasize the nature of research in these disciplines. Still others focus on relating a practical application to science and technology. And, of great importance to the success of the program are the interfaces between the various stages. Successfully managing these transitions is a requirement for producing trained scientists, engineers and technologists. Presentations describing the CARET program have been given at this year's HBCU Research Conference at the Ohio Aerospace Institute and as a seminar in the Solar Circle Seminar series of the Photovoltaic and Space Environments Branch at NASA Lewis Research Center. In this report, we will describe the many positive achievements toward the fulfillment of the goals and outcomes of our program. We will begin with a description of the interactions among the consortium members and end with a description of the activities of each of the member institutions .

  9. Biomineralization and formulation of endosulfan degrading bacterial and fungal consortiums.

    Science.gov (United States)

    Abraham, Jayanthi; Silambarasan, Sivagnanam

    2014-11-01

    Microbial degradation offers an effective approach to remove toxicants and in this study, a microbial consortium consisting of bacterial strains and fungal strains were originally obtained from endosulfan contaminated agricultural soils. Identification of the bacterial isolates by 16S rRNA sequences revealed the isolates to be Halophilic bacterium JAS4, Klebsiella pneumoniae JAS8, Enterobacter asburiae JAS5, and Enterobacter cloacae JAS7, whereas the fungal isolates were identified by 18S rRNA sequences and the isolates were Botryosphaeria laricina JAS6, Aspergillus tamarii JAS9 and Lasiodiplodia sp. JAS12. The biodegradation of endosulfan was monitored by using HPLC and FTIR analysis. The bacterial and fungal consortium could degrade 1000 mg l(-1) of endosulfan efficiently in aqueous medium and in soil. The infrared spectrum of endosulfan degraded samples in the aqueous medium by bacterial and fungal consortium showed bands at 1400 and 950 cm(-1) which are the characteristics of COOH group and acid dimer band respectively. In the present investigation, low cost solid materials such as sawdust, soil, fly ash, molasses and nutrients were used for the formulation of microbial consortium and to achieve greater multiplication and survival of the microbial strains. PMID:25454517

  10. Improving safety of aircraft engines: a consortium approach

    Science.gov (United States)

    Brasche, Lisa J. H.

    1996-11-01

    With over seven million departures per year, air transportation has become not a luxury, but a standard mode of transportation for the United States. A critical aspect of modern air transport is the jet engine, a complex engineered component that has enabled the rapid travel to which we have all become accustomed. One of the enabling technologies for safe air travel is nondestructive evaluation, or NDE, which includes various inspection techniques used to assess the health or integrity of a structure, component, or material. The Engine Titanium Consortium (ETC) was established in 1993 to respond to recommendations made by the Federal Aviation Administration (FAA) Titanium Rotating Components Review Team (TRCRT) for improvements in inspection of engine titanium. Several recent accomplishments of the ETC are detailed in this paper. The objective of the Engine Titanium Consortium is to provide the FAAand the manufacturers with reliable and costeffective new methods and/or improvements in mature methods for detecting cracks, inclusions, and imperfections in titanium. The consortium consists of a team of researchers from academia and industry-namely, Iowa State University, Allied Signal Propulsion Engines, General Electric Aircraft Engines, and Pratt & Whitney Engines-who work together to develop program priorities, organize a program plan, conduct the research, and implement the solutions. The true advantage of the consortium approach is that it brings together the research talents of academia and the engineering talents of industry to tackle a technology-base problem. In bringing industrial competitors together, the consortium ensures that the research results, which have safety implications and result from FAA funds, are shared and become part of the public domain.

  11. 25 CFR 1000.23 - How is a Tribe/Consortium admitted to the applicant pool?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false How is a Tribe/Consortium admitted to the applicant pool... Admission into the Applicant Pool § 1000.23 How is a Tribe/Consortium admitted to the applicant pool? To be considered for admission in the applicant pool, a Tribe/Consortium must submit an application to the...

  12. 76 FR 38666 - Food and Drug Administration (FDA) and Marine Environmental Sciences Consortium/Dauphin Island...

    Science.gov (United States)

    2011-07-01

    ... Nutrition (CFSAN) and the Marine Environmental Sciences Consortium/Dauphin Island Sea Lab (DISL). The goal... Marine Environmental Science Consortium-Dauphin Island Sea Lab (DISL) will greatly contribute to FDA's... Objectives FDA Gulf Coast Seafood Laboratory (GCSL) and the Marine Environmental Science Consortium of...

  13. 77 FR 43237 - Genome in a Bottle Consortium-Work Plan Review Workshop

    Science.gov (United States)

    2012-07-24

    ... National Institute of Standards and Technology Genome in a Bottle Consortium--Work Plan Review Workshop.... SUMMARY: NIST announces the Genome in a Bottle Consortium meeting to be held on Thursday and Friday, August 16 and 17, 2012. The Genome in a Bottle Consortium is planning to develop the reference...

  14. 78 FR 47674 - Genome in a Bottle Consortium-Progress and Planning Workshop

    Science.gov (United States)

    2013-08-06

    ... National Institute of Standards and Technology Genome in a Bottle Consortium--Progress and Planning... workshop. SUMMARY: NIST announces the Genome in a Bottle Consortium meeting to be held on Thursday and Friday, August 15 and 16, 2013. The Genome in a Bottle Consortium is developing the reference...

  15. A University Consortium on Homogeneous Charge Compression Ignition Engine Research

    Energy Technology Data Exchange (ETDEWEB)

    Assanis, Dennis; Atreya, Arvind; Bowman, Craig; Chen, Jyh-Yuan; Cheng, Wai; Davidson, David; Dibble, Robert; Edwards, Chris; Filipi, Zoran; Golden, David; Green, William; Hanson, Ronald; Hedrick, J Karl; Heywood, John; Im, Hong; Lavoie, George; Sick, Volker; Wooldridge, Margaret

    2007-03-31

    Over the course of this four year project, the consortium team members from UM, MIT, Stanford, and Berkeley along with contributors from Sandia National Labs and LLNL, have produced a wide range of results on gasoline HCCI control and implementation. The work spanned a wide range of activities including engine experiments, fundamental chemical kinetics experiments, and an array of analytical modeling techniques and simulations. Throughout the project a collaborative approach has produced a many significant new insights into HCCI engines and their behavior while at the same time we achieved our key consortium goal: to develop workable strategies for gasoline HCCI control and implementation. The major accomplishments in each task are summarized, followed by detailed discussion.

  16. FLYSUB-Consortium Tracking and RICH Performance Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Soha, Aria [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Azumoun, Bob [Brookhaven National Lab. (BNL), Upton, NY (United States); Blatnik, Marie [Brookhaven National Lab. (BNL), Upton, NY (United States); Pak, Robert [Brookhaven National Lab. (BNL), Upton, NY (United States); Purschke, Martin [Brookhaven National Lab. (BNL), Upton, NY (United States); Di Ruzza, Benedetto [Brookhaven National Lab. (BNL), Upton, NY (United States); Woody, Craig [Brookhaven National Lab. (BNL), Upton, NY (United States); Bhopatkar, Vallary [Florida Inst. of Technology, Melbourne, FL (United States); Hohlmann, Marcus [Florida Inst. of Technology, Melbourne, FL (United States); Twigger, Jessie [Florida Inst. of Technology, Melbourne, FL (United States); Zhang, Aiwu [Florida Inst. of Technology, Melbourne, FL (United States); Dehmelt, Klaus [Stony Brook Univ., NY (United States); Deshpande, Abhay [Stony Brook Univ., NY (United States); Feege, Nils [Stony Brook Univ., NY (United States); Hemmick, Thomas [Stony Brook Univ., NY (United States); Bai, Xinzhang [Univ. of Virginia, Charlottesville, VA (United States); Gnanvo, Kondo [Univ. of Virginia, Charlottesville, VA (United States); Gu, Chao [Univ. of Virginia, Charlottesville, VA (United States); Liyanage, Nilanga [Univ. of Virginia, Charlottesville, VA (United States); Majka, Richard [Yale Univ., New Haven, CT (United States); Smirnov, Nikolai [Yale Univ., New Haven, CT (United States)

    2013-09-23

    This is a technical scope of work (TSW) between the Fermi National Accelerator Laboratory (Fermilab) and the experiments of FLYSUB-Consortium who have committed to participate in beam tests to be carried out during the 2013-2014 Fermilab Test Beam Facility program. The ultimate goal of this test-beam effort is to test and verify the performance of the individual components according to their expectation.

  17. The Toxicology Investigators Consortium Case Registry—The 2012 Experience

    OpenAIRE

    Wiegand, Timothy; Wax, Paul; Smith, Eric; Hart, Katherine; Brent, Jeffrey

    2013-01-01

    In 2010, the American College of Medical Toxicology (ACMT) established its Case Registry, the Toxicology Investigators Consortium (ToxIC). All cases are entered prospectively and include only suspected and confirmed toxic exposures cared for at the bedside by board-certified or board-eligible medical toxicologists at its participating sites. The primary aims of establishing this Registry include the development of a realtime toxico-surveillance system in order to identify and describe current...

  18. Brain Vascular Malformation Consortium: Overview, Progress and Future Directions

    OpenAIRE

    Akers, Amy L.; Ball, Karen L.; Clancy, Marianne; Comi, Anne M.; Faughnan, Marie E.; Gopal-Srivastava, Rashmi; Jacobs, Thomas P.; Kim, Helen; Krischer, Jeffrey; Marchuk, Douglas A.; Charles E McCulloch; Morrison, Leslie; Moses, Marsha; Moy, Claudia S.; Pawlikowska, Ludmilla

    2013-01-01

    Brain vascular malformations are resource-intensive to manage effectively, are associated with serious neurological morbidity, lack specific medical therapies, and have no validated biomarkers for disease severity and progression. Investigators have tended to work in “research silos” with suboptimal cross-communication. We present here a paradigm for interdisciplinary collaboration to facilitate rare disease research. The Brain Vascular Malformation Consortium (BVMC) is a multidisciplinary, i...

  19. p-Cresol mineralization by a nitrifying consortium

    International Nuclear Information System (INIS)

    Nitrification and denitrification processes are considered economically feasible technologies for nitrogen removal from wastewater. Knowledge of the toxic or inhibitory effects of cresols on the nitrifying respiratory process is still insufficient. The aim of this study was to evaluate the kinetic behavior and oxidizing ability of a nitrifying consortium exposed to p-cresol in batch cultures. Biotransformation of p-cresol was investigated by identifying the different intermediates formed. (Author)

  20. Cultivation of algae consortium in a dairy farm wastewater for biodiesel production

    Directory of Open Access Journals (Sweden)

    S. Hena

    2015-06-01

    Full Text Available Dairy farm wastewaters are potential resources for production of microalgae biofuels. A study was conducted to evaluate the capability of production of biodiesel from consortium of native microalgae culture in dairy farm treated wastewater. Native algal strains were isolated from dairy farm wastewaters collection tank (untreated wastewater as well as from holding tank (treated wastewater. The consortium members were selected on the basis of fluorescence response after treating with Nile red reagent. Preliminary studies of two commercial and consortium of ten native strains of algae showed good growth in wastewaters. A consortium of native strains was found capable to remove more than 98% nutrients from treated wastewater. The biomass production and lipid content of consortium cultivated in treated wastewater were 153.54 t ha−1 year−1 and 16.89%, respectively. 72.70% of algal lipid obtained from consortium could be converted into biodiesel.

  1. Microbial dehalogenation of trichlorophenol by a bacterial consortium: characterization and mechanism

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    Chlorinated phenolic compounds are a class of toxic and refractory organic pollutants. The pollution caused by chlorophenols poses serious ecological and environmental problems. A stable bacterial consortium capable of reductively dechlorinating trichlorophenol was isolated using chlorophenol as the sole source of carbon and energy. The physiological characteristics of the mixed cultures were studied and the results show that the consortium could use pyruvate as the carbon and energy source. The fermentation of pyruvate, sulfate reduction and dechlorination process proceeded strictly in succession within this consortium. The effect of specific inhibitors on the dechlorinating activity of the consortium was investigated, and the results indicate that sulfate and molybdate (1 mmol/L) have a strong inhibitive influence on the dechlorination activity. Fluorescence in situ hybridization (FISH) technique was applied to analyzing the composition of the consortium and the results reveal that one major subpopulation within the consortium was phylogenetically affiliated to gamma and delta subclass of Proteobacteria.

  2. Kansas Consortium Plug-in Hybrid Medium Duty

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2012-03-31

    On September 30, 2008, the US Department of Energy (DoE), issued a cooperative agreement award, DE-FC26-08NT01914, to the Metropolitan Energy Center (MEC), for a project known as “Kansas Consortium Plug-in Hybrid Medium Duty Certification” project. The cooperative agreement was awarded pursuant to H15915 in reference to H. R. 2764 Congressionally Directed Projects. The original agreement provided funding for The Consortium to implement the established project objectives as follows: (1) to understand the current state of the development of a test protocol for PHEV configurations; (2) to work with industry stakeholders to recommend a medium duty vehicle test protocol; (3) to utilize the Phase 1 Eaton PHEV F550 Chassis or other appropriate PHEV configurations to conduct emissions testing; (4) and to make an industry PHEV certification test protocol recommendation for medium duty trucks. Subsequent amendments to the initial agreement were made, the most significant being a revised Scope of Project Objectives (SOPO) that did not address actual field data since it was not available as originally expected. This project was mated by DOE with a parallel project award given to the South Coast Air Quality Management District (SCAQMD) in California. The SCAQMD project involved designing, building and testing of five medium duty plug-in hybrid electric trucks. SCAQMD had contracted with the Electric Power Research Institute (EPRI) to manage the project. EPRI provided the required match to the federal grant funds to both the SCAQMD project and the Kansas Consortium project. The rational for linking the two projects was that the data derived from the SCAQMD project could be used to validate the protocols developed by the Kansas Consortium team. At the same time, the consortium team would be a useful resource to SCAQMD in designating their test procedures for emissions and operating parameters and determining vehicle mileage. The years between award of the cooperative

  3. Geodesy and the UNAVCO Consortium: Three Decades of Innovations

    Science.gov (United States)

    Rowan, L. R.; Miller, M. M.; Meertens, C. M.; Mattioli, G. S.

    2015-12-01

    UNAVCO, a non-profit, university consortium that supports geoscience research using geodesy, began with the ingenious recognition that the nascent Global Positioning System constellation (GPS) could be used to investigate earth processes. The consortium purchased one of the first commercially available GPS receivers, Texas Instrument's TI-4100 NAVSTAR Navigator, in 1984 to measure plate deformation. This early work was highlighted in a technology magazine, GPSWorld, in 1990. Over a 30-year period, UNAVCO and the community have helped advance instrument design for mobility, flexibility, efficiency and interoperability, so research could proceed with higher precision and under ever challenging conditions. Other innovations have been made in data collection, processing, analysis, management and archiving. These innovations in tools, methods and data have had broader impacts as they have found greater utility beyond research for timing, precise positioning, safety, communication, navigation, surveying, engineering and recreation. Innovations in research have expanded the utility of geodetic tools beyond the solid earth science through creative analysis of the data and the methods. For example, GPS sounding of the atmosphere is now used for atmospheric and space sciences. GPS reflectrometry, another critical advance, supports soil science, snow science and ecological research. Some research advances have had broader impacts for society by driving innovations in hazards risk reduction, hazards response, resource management, land use planning, surveying, engineering and other uses. Furthermore, the geodetic data is vital for the design of space missions, testing and advancing communications, and testing and dealing with interference and GPS jamming. We will discuss three decades (and counting) of advances by the National Science Foundation's premiere geodetic facility, consortium and some of the many geoscience principal investigators that have driven innovations in

  4. Overview of the Type I Diabetes Genetics Consortium.

    Science.gov (United States)

    Rich, S S; Akolkar, B; Concannon, P; Erlich, H; Hilner, J E; Julier, C; Morahan, G; Nerup, J; Nierras, C; Pociot, F; Todd, J A

    2009-12-01

    The Type I Diabetes Genetics Consortium (T1DGC) is an international, multicenter research program with two primary goals. The first goal is to identify genomic regions and candidate genes whose variants modify an individual's risk of type I diabetes (T1D) and help explain the clustering of the disease in families. The second goal is to make research data available to the research community and to establish resources that can be used by, and that are fully accessible to, the research community. To facilitate the access to these resources, the T1DGC has developed a Consortium Agreement (http://www.t1dgc.org) that specifies the rights and responsibilities of investigators who participate in Consortium activities. The T1DGC has assembled a resource of affected sib-pair families, parent-child trios, and case-control collections with banks of DNA, serum, plasma, and EBV-transformed cell lines. In addition, both candidate gene and genome-wide (linkage and association) studies have been performed and displayed in T1DBase (http://www.t1dbase.org) for all researchers to use in their own investigations. In this supplement, a subset of the T1DGC collection has been used to investigate earlier published candidate genes for T1D, to confirm the results from a genome-wide association scan for T1D, and to determine associations with candidate genes for other autoimmune diseases or with type II diabetes that may be involved with beta-cell function.

  5. The IRIS consortium: international cooperation in advanced reactor development

    International Nuclear Information System (INIS)

    Besides its many outstanding technical innovations in the design and safety, the most innovative feature of the International Reactor Innovative and Secure (IRIS), is perhaps the international cooperation which carries on its development. IRIS is designed by an international consortium which currently numbers 21 organizations from ten countries across four continents. It includes reactor, fuel and fuel cycle vendors, component manufacturers, laboratories, academia, architect engineers and power producers. The defining organizational characteristics of IRIS is that while Westinghouse has overall lead and responsibility, this lead is of the type of 'primus inter pares' (first among equals) rather than the traditional owner versus suppliers/contractors relationship. All members of the IRIS consortium contribute and expect to have a return, should IRIS be successfully deployed, commensurate to their investment. The nature of such return will be tailored to the type of each organization, because it will of course be of a different nature for say a component manufacturer, university, or architect engineer. One fundamental tenet of the consortium is that all members, regardless of their amount of contribution, have equal access to all information developed within the project. Technical work is thus being coordinated by integrated subgroups and the whole team meets twice a year to perform an overall review of the work, discuss policy and strategy and plan future activities. Personnel from consortium members have performed internships, mostly at Westinghouse locations in Pittsburgh, Pennsylvania, and Windsor, Connecticut, but also at other members, as it has been the case for several graduate students. In fact, more than one hundred students at the various universities have been working on IRIS, most of them conducting graduate theses at the master or doctoral level. The IRIS experience has proved very helpful to the students in successfully landing their employment choice

  6. Overview of the Type I Diabetes Genetics Consortium

    OpenAIRE

    Rich, SS; Akolkar, B; Concannon, P; Erlich, H.; Hilner, JE; Julier, C.; Morahan, G; J. Nerup; Nierras, C.; Pociot, F; Todd, JA.

    2009-01-01

    The Type I Diabetes Genetics Consortium (T1DGC) is an international, multicenter research program with two primary goals. The first goal is to identify genomic regions and candidate genes whose variants modify an individual’s risk of type I diabetes (T1D) and help explain the clustering of the disease in families. The second goal is to make research data available to the research community and to establish resources that can be used by, and that are fully accessible to, the research community...

  7. Decolorization and biodegradation of reactive dyes and dye wastewater by a developed bacterial consortium.

    Science.gov (United States)

    Saratale, R G; Saratale, G D; Chang, J S; Govindwar, S P

    2010-11-01

    A bacterial consortium (consortium GR) consisting of Proteus vulgaris NCIM-2027 and Micrococcus glutamicus NCIM-2168 could rapidly decolorize and degrade commonly-used sulfonated reactive dye Green HE4BD and many other reactive dyes. Consortium GR shows markedly higher decolorization activity than that of the individual strains. The preferable physicochemical parameters were identified to achieve higher dye degradation and decolorization efficiency. The supplementation of cheap co-substrates (e.g., extracts of agricultural wastes) could enhance the decolorization performance of consortium GR. Extent of mineralization was determined with TOC and COD measurements, showing nearly complete mineralization of Green HE4BD by consortium GR (up to 90% TOC and COD reduction) within 24 h. Oxidoreductive enzymes seemed to be involved in fast decolorization/degradation process with the evidence of enzymes induction in the bacterial consortium. Phytotoxicity and microbial toxicity studies confirm that the biodegraded products of Green HE4BD by consortium GR are non-toxic. Consortium GR also shows significant biodegradation and decolorization activities for mixture of reactive dyes as well as the effluent from actual dye manufacturing industry. This confers the possibility of applying consortium GR for the treatment of industrial wastewaters containing dye pollutants.

  8. Multiple Syntrophic Interactions in a Terephthalate-Degrading Methanogenic Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Lykidis, Athanasios; Chen, Chia-Lung; Tringe, Susannah G.; McHardy, Alice C.; Copeland, Alex 5; Kyrpides, Nikos C.; Hugenholtz, Philip; Liu, Wen-Tso

    2010-08-05

    Terephthalate (TA) is one of the top 50 chemicals produced worldwide. Its production results in a TA-containing wastewater that is treated by anaerobic processes through a poorly understood methanogenic syntrophy. Using metagenomics, we characterized the methanogenic consortium tinside a hyper-mesophilic (i.e., between mesophilic and thermophilic), TA-degrading bioreactor. We identified genes belonging to dominant Pelotomaculum species presumably involved in TA degradation through decarboxylation, dearomatization, and modified ?-oxidation to H{sub 2}/CO{sub 2} and acetate. These intermediates are converted to CH{sub 4}/CO{sub 2} by three novel hyper-mesophilic methanogens. Additional secondary syntrophic interactions were predicted in Thermotogae, Syntrophus and candidate phyla OP5 and WWE1 populations. The OP5 encodes genes capable of anaerobic autotrophic butyrate production and Thermotogae, Syntrophus and WWE1 have the genetic potential to oxidize butyrate to COsub 2}/H{sub 2} and acetate. These observations suggest that the TA-degrading consortium consists of additional syntrophic interactions beyond the standard H{sub 2}-producing syntroph ? methanogen partnership that may serve to improve community stability.

  9. The Latin American Consortium of Studies in Obesity (LASO)

    Science.gov (United States)

    Bautista, L. E.; Casas, J. P.; Herrera, V. M.; Miranda, J. J.; Perel, P.; Pichardo, R.; González, A.; Sanchez, J. R.; Ferreccio, C.; Aguilera, X.; Silva, E.; Oróstegui, M.; Gómez, L. F.; Chirinos, J. A.; Medina-Lezama, J.; Pérez, C. M.; Suárez, E.; Ortiz, A. P.; Rosero, L.; Schapochnik, N.; Ortiz, Z.; Ferrante, D.

    2009-01-01

    Summary Current, high-quality data are needed to evaluate the health impact of the epidemic of obesity in Latin America. The Latin American Consortium of Studies of Obesity (LASO) has been established, with the objectives of (i) Accurately estimating the prevalence of obesity and its distribution by sociodemographic characteristics; (ii) Identifying ethnic, socioeconomic and behavioural determinants of obesity; (iii) Estimating the association between various anthropometric indicators or obesity and major cardiovascular risk factors and (iv) Quantifying the validity of standard definitions of the various indexes of obesity in Latin American population. To achieve these objectives, LASO makes use of individual data from existing studies. To date, the LASO consortium includes data from 11 studies from eight countries (Argentina, Chile, Colombia, Costa Rica, Dominican Republic, Peru, Puerto Rico and Venezuela), including a total of 32 462 subjects. This article describes the overall organization of LASO, the individual studies involved and the overall strategy for data analysis. LASO will foster the development of collaborative obesity research among Latin American investigators. More important, results from LASO will be instrumental to inform health policies aiming to curtail the epidemic of obesity in the region. PMID:19438980

  10. Inner-City Energy and Environmental Education Consortium

    Energy Technology Data Exchange (ETDEWEB)

    1993-06-11

    The numbers of individuals with adequate education and training to participate effectively in the highly technical aspects of environmental site cleanup are insufficient to meet the increasing demands of industry and government. Young people are particularly sensitive to these issues and want to become better equipped to solve the problems which will confront them during their lives. Educational institutions, on the other hand, have been slow in offering courses and curricula which will allow students to fulfill these interests. This has been in part due to the lack of federal funding to support new academic programs. This Consortium has been organized to initiate focused educational effort to reach inner-city youth with interesting and useful energy and environmental programs which can lead to well-paying and satisfying careers. Successful Consortium programs can be replicated in other parts of the nation. This report describes a pilot program in Washington, DC, Philadelphia, and Baltimore with the goal to attract and retain inner-city youth to pursue careers in energy-related scientific and technical areas, environmental restoration, and waste management.

  11. A programmable Escherichia coli consortium via tunable symbiosis.

    Directory of Open Access Journals (Sweden)

    Alissa Kerner

    Full Text Available Synthetic microbial consortia that can mimic natural systems have the potential to become a powerful biotechnology for various applications. One highly desirable feature of these consortia is that they can be precisely regulated. In this work we designed a programmable, symbiotic circuit that enables continuous tuning of the growth rate and composition of a synthetic consortium. We implemented our general design through the cross-feeding of tryptophan and tyrosine by two E. coli auxotrophs. By regulating the expression of genes related to the export or production of these amino acids, we were able to tune the metabolite exchanges and achieve a wide range of growth rates and strain ratios. In addition, by inverting the relationship of growth/ratio vs. inducer concentrations, we were able to "program" the co-culture for pre-specified attributes with the proper addition of inducing chemicals. This programmable proof-of-concept circuit or its variants can be applied to more complex systems where precise tuning of the consortium would facilitate the optimization of specific objectives, such as increasing the overall efficiency of microbial production of biofuels or pharmaceuticals.

  12. The Launch of the Philadelphia Education Research Consortium: Lessons Learned from the First Year of Implementation

    Science.gov (United States)

    Shaw, Kate

    2016-01-01

    The Philadelphia Education Research Consortium (PERC) was launched in July 2014 as an innovative place-based consortium of educational research partners from multiple sectors. Its primary objective is to provide research and analyses on some of the city's most pressing education issues. As such, PERC's research agenda is driven by both traditional…

  13. Isolation and Characteristics of a Microbial Consortium for Effectively Degrading Phenanthrene

    Institute of Scientific and Technical Information of China (English)

    Wang Jing; Xu Hongke; Guo Shaohui

    2007-01-01

    A microbial consortium (named W4) capable of aerobic biodegradation of solid phenanthrene as the sole source of carbon and energy was isolated by selective enrichment from petroleum-contaminated soil in the Henan oilfield,China. The strains of the consortium were identified as Sphingomonas cloacae, Rhizobium sp., Pseudomonas aeruginosa and Achromobacter xylosoxidans respectively by means of genetic methods. The major metabolites of phenanthrene were analyzed by gas chromatography-mass spectrometry (GC-MS). The biodegradation percentage of solid phenanthrene at 200 mg/L in liquid medium after 7 days of growth was greater than 99%. The degradation of phenanthrene was compared between individual predominant strains and the microbial consortium in different treatment processes. The microbial consortium showed a significant improvement of phenanthrene degradation rates in either static or shaking culture. The degradation percentage of phenanthrene by the consortium W4 decreased to some degree when C 16 coexisted, however it was hardly affected by C30. Furthermore, the ability of consortium W4 to remediate oil sludge from the Dagang oil refinery was studied by composting; and it was found that the consortium W4 could obviously remove polycyclic aromatic hydrocarbons (PAHs) and paraffinic hydrocarbons. All the results indicated that the microbial consortium W4 had a promising application in bioremediation of oil-contaminated environments and could be potentially used in microbial enhanced oil recovery (MEOR).

  14. 11th Annual NIH Pain Consortium Symposium on Advances in Pain Research | Division of Cancer Prevention

    Science.gov (United States)

    The NIH Pain Consortium will convene the 11th Annual NIH Pain Consortium Symposium on Advances in Pain Research, featuring keynote speakers and expert panel sessions on Innovative Models and Methods. The first keynote address will be delivered by David J. Clark, MD, PhD, Stanford University entitled “Challenges of Translational Pain Research: What Makes a Good Model?” |

  15. 77 FR 38770 - Notice of Consortium on “nSoft Consortium”

    Science.gov (United States)

    2012-06-29

    ... thereafter. Non-profit organizations in lieu of membership fees will contribute personal expertise and... meeting, revisions have ] been made to the membership fee structure and the initial period of time for the consortium. Also, the consortium is open to a limited number of for-profit and not-for-profit...

  16. The Activities of the European Consortium on Nuclear Data Development and Analysis for Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, U., E-mail: ulrich.fischer@kit.edu [Karlsruhe Institute of Technology, Institute for Neutron Physic and Reactor Technology, 76344 Eggenstein-Leopoldshafen (Germany); Avrigeanu, M.; Avrigeanu, V. [Horia Hulubei National Institute of Physics and Nuclear Engineering (IFIN-HH), RO-077125 Magurele (Romania); Cabellos, O. [Departamento de Ingenieria Nuclear, Universidad Politecnica de Madrid, 28006 Madrid (Spain); Kodeli, I. [Jozef Stefan Institute (JSI), Jamova 39, 1000 Ljubljana (Slovenia); Koning, A. [Nuclear Research and Consultancy Group (NRG), Westerduinweg 3, 1755 LE Petten (Netherlands); Konobeyev, A.Yu. [Karlsruhe Institute of Technology, Institute for Neutron Physic and Reactor Technology, 76344 Eggenstein-Leopoldshafen (Germany); Leeb, H. [Technische Universitaet Wien, Atominstitut, Wiedner Hauptstrasse 8–10, 1040 Wien (Austria); Rochman, D. [Nuclear Research and Consultancy Group (NRG), Westerduinweg 3, 1755 LE Petten (Netherlands); Pereslavtsev, P. [Karlsruhe Institute of Technology, Institute for Neutron Physic and Reactor Technology, 76344 Eggenstein-Leopoldshafen (Germany); Sauvan, P. [Universidad Nacional de Educacion a Distancia, C. Juan del Rosal, 12, 28040 Madrid (Spain); Sublet, J.-C. [Euratom/CCFE Fusion Association, Culham Science Centre, OX14 3DB (United Kingdom); Trkov, A. [Jozef Stefan Institute (JSI), Jamova 39, 1000 Ljubljana (Slovenia); Dupont, E. [OECD Nuclear Energy Agency, Paris (France); Leichtle, D.; Izquierdo, J. [Fusion for Energy, Barcelona (Spain)

    2014-06-15

    This paper presents an overview of the activities of the European Consortium on Nuclear Data Development and Analysis for Fusion. The Consortium combines available European expertise to provide services for the generation, maintenance, and validation of nuclear data evaluations and data files relevant for ITER, IFMIF and DEMO, as well as codes and software tools required for related nuclear calculations.

  17. The fungal consortium of Andromeda polifolia in bog habitats

    Directory of Open Access Journals (Sweden)

    N.V. Filippova

    2015-09-01

    Full Text Available (1 Andromeda polifolia (bog rosemary is a common plant species in northern circumboreal peatlands. While not a major peat-forming species in most peatlands, it is characterised by a substantial woody below-ground biomass component that contributes directly to the accumulation of organic matter below the moss surface, as well as sclerophyllous leaf litter that contributes to the accumulation of organic matter above the moss surface. Rather little is known about the fungal communities associated with this plant species. Hence, we investigated the fungal consortium of A. polifolia in three distinct vegetation communities of ombrotrophic bogs near Khanty-Mansiysk, West Siberia, Russia, in 2012 and 2013. These vegetation communities were forested bog (Tr = treed, Sphagnum-dominated lawn (Ln, and Eriophorum-Sphagnum-dominated hummock (Er. (2 In total, 37 fungal taxa, belonging to five classes and 16 families, were identified and described morphologically. Seven fungal species were previously known from Andromeda as host. Others are reported for the first time, thus considerably expanding the fungal consortium of this dwarf shrub. Most taxa were saprobic on fallen leaves of A. polifolia found amongst Sphagnum in the bog. Two taxa were parasitic on living plant tissues and one taxon was saprobic on dead twigs. Three taxa, recorded only on A. polifolia leaves and on no other plant species or materials, may be host-specific to this dwarf shrub. (3 A quantitative analysis of the frequency of occurrence of all taxa showed that one taxon (Coccomyces duplicarioides was very abundant, 64 % of the taxa occurred frequently, and 32 % of the taxa occurred infrequently. The mean Shannon diversity index of the community was 2.4. (4 There were no statistical differences in the fungal community composition of A. polifolia in the three vegetation communities investigated in this study. Redundancy analysis suggested that some fungal taxa were positively, and others

  18. Experience of the Paris Research Consortium Climate-Environment-Society

    Science.gov (United States)

    Joussaume, Sylvie; Pacteau, Chantal; Vanderlinden, Jean Paul

    2016-04-01

    It is now widely recognized that the complexity of climate change issues translates itself into a need for interdisciplinary approaches to science. This allows to first achieve a more comprehensive vision of climate change and, second, to better inform the decision-making processes. However, it seems that willingness alone is rarely enough to implement interdisciplinarity. The purpose of this presentation is to mobilize reflexivity to revisit and analyze the experience of the Paris Consortium for Climate-Environment-Society. The French Consortium Climate-Environment-Society aims to develop, fund and coordinate interdisciplinary research into climate change and its impacts on society and environment. Launched in 2007, the consortium relies on the research expertise of 17 laboratories and federation in the Paris area working mainly in the fields of climatology, hydrology, ecology, health sciences, and the humanities and social sciences. As examples, economists and climatologists have studied greenhouse gas emission scenarios compatible with climate stabilization goals. Historical records have provided both knowledge about past climate change and vulnerability of societies. Some regions, as the Mediterranean and the Sahel, are particularly vulnerable and already have to cope with water availability, agricultural production and even health issues. A project showed that millet production in West Africa is expected to decline due to warming in a higher proportion than observed in recent decades. Climate change also raises many questions concerning health: combined effects of warming and air quality, impacts on the production of pollens and allergies, impacts on infectious diseases. All these issues lead to a need for approaches integrating different disciplines. Furthermore, climate change impacts many ecosystems which, in turn, affect its evolution. Our experience shows that interdisciplinarity supposes, in order to take shape, the conjunction between programming

  19. 25 CFR 1000.16 - What criteria must a Tribe/Consortium satisfy to be eligible for admission to the “applicant pool”?

    Science.gov (United States)

    2010-04-01

    .../Consortium satisfy to be eligible for admission to the “applicant pool”? To be admitted into the applicant pool, a Tribe/Consortium must either be an Indian Tribe or a Consortium of Indian Tribes and...

  20. CREAT A CONSORTIUM AND DEVELOP PREMIUM CARBON PRODUCTS FROM COAL

    Energy Technology Data Exchange (ETDEWEB)

    John M. Andresen

    2003-08-01

    The Consortium for Premium Carbon Products from Coal, with funding from the U.S. Department of Energy's National Energy Technology Laboratory and matching funds from industry and academic institutions continued to excel in developing innovative technologies to use coal and coal-derived feedstocks to produce premium carbon product. During Budget Period 5, eleven projects were supported and sub-contracted were awarded to seven organizations. The CPCPC held two meetings and one tutorial at various locations during the year. Budget Period 5 was a time of growth for CPCPC in terms of number of proposals and funding requested from members, projects funded and participation during meetings. Although the membership was stable during the first part of Budget Period 5 an increase in new members was registered during the last months of the performance period.

  1. Advances in Metal Supported Cells in the METSOFC EU Consortium

    DEFF Research Database (Denmark)

    McKenna, Brandon J.; Christiansen, Niels; Schauperl, Richard;

    2012-01-01

    Employing a mechanically robust metal support as the structural element in SOFC has been the objective of various development efforts. The EU-sponsored project “METSOFC”, completed at the end of 2011, resulted in a number of advancements towards implementing this strategy. These include robust...... metal supported cells (MSCs) having low ASR at low temperature, incorporation into small stacks of powers approaching ½kW, and stack tolerance to various operation cycles. DTU Energy Conversion's (formerly Risø DTU) research into planar MSCs has produced an advanced cell design with high performance...... outcomes of the METSOFC consortium are covered, along with associated work supported by the Danish National Advanced Technology Foundation....

  2. Creating Future Stem Leaders: The National Astronomy Consortium:

    Science.gov (United States)

    Sheth, Kartik; Mills, Elisabeth A. C.; Boyd, Patricia T.; Strolger, Louis-Gregory; Benjamin, Robert A.; Brisbin, Drew; Giles, Faye; National Astronomy Consortium

    2016-01-01

    The National Astronomy Consortium (NAC) is a program led by the National Radio Astronomy Observatory (NRAO) and Associated Universities Inc., (AUI) in partnership with the National Society of Black Physicists (NSBP), and a number of minority and majority universities to increase the numbers of students from underrepresented groups and those otherwise overlooked by the traditional academic pipeline into STEM or STEM-related careers. The seed for the NAC was a partnership between NRAO and Howard University which began with an exchange of a few summer students five years ago. Since then the NAC has grown tremendously. Today the NAC aims to host between 4 to 5 cohorts nationally in an innovative model in which the students are mentored throughout the year with multiple mentors and peer mentoring, continued engagement in research and professional development / career training throughout the academic year and throughout their careers. We will summarize the results from this innovative and highly succesful program and provide lessons learned.

  3. The CEPH consortium linkage map of human chromosome 13

    Energy Technology Data Exchange (ETDEWEB)

    Bowcock, A.M.; Barnes, R.I. [Univ. of Texas Southwestern Medical Center, Dallas, TX (United States); Gerken, S.C.; Leppert, M. [Univ. of Utah School of Medicine, Salt Lake City, UT (United States); Shiang, R. [Univ. of Iowa, Iowa City, IA (United States); Jabs, E.W.; Warren, A.C.; Antonarakis, S. [Johns Hopkins School of Medicine, Baltimore, MD (United States); Retief, A.E. [Univ. of Stellenbosch, Tygerberg (South Africa); Vergnaud, G. [Centre d`Etudes du Bouchet, Vert le Petit (France)] [and others

    1993-05-01

    The CEPH consortium map of chromosome 13 is presented. This map contains 59 loci defined by genotypes generated from CEPH family DNAs with 94 different probe and restriction enzyme combinations contributed by 9 laboratories. A total of 25 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from loci in the centromeric region of chromosome 13 to the terminal band of the long arm. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 158, 203, and 178cM respectively. The largest interval is 24 cM and is between D13Z1 (alphaRI) and ATP1AL1. The mean genetic distance between the 25 uniquely placed loci is 7 cM. 76 refs., 3 figs., 5 tabs.

  4. Consortium for Algal Biofuel Commercialization (CAB-COMM) Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Mayfield, Stephen P. [Univ. of California, San Diego, CA (United States)

    2015-12-04

    The Consortium for Algal Biofuel Commercialization (CAB-Comm) was established in 2010 to conduct research to enable commercial viability of alternative liquid fuels produced from algal biomass. The main objective of CAB-Comm was to dramatically improve the viability of algae as a source of liquid fuels to meet US energy needs, by addressing several significant barriers to economic viability. To achieve this goal, CAB-Comm took a diverse set of approaches on three key aspects of the algal biofuels value chain: crop protection; nutrient utilization and recycling; and the development of genetic tools. These projects have been undertaken as collaboration between six academic institutions and two industrial partners: University of California, San Diego; Scripps Institution of Oceanography; University of Nebraska, Lincoln; Rutgers University; University of California, Davis; Johns Hopkins University; Sapphire Energy; and Life Technologies.

  5. On the Need to Establish an International Soil Modeling Consortium

    Science.gov (United States)

    Vereecken, H.; Vanderborght, J.; Schnepf, A.

    2014-12-01

    Soil is one of the most critical life-supporting compartments of the Biosphere. Soil provides numerous ecosystem services such as a habitat for biodiversity, water and nutrients, as well as producing food, feed, fiber and energy. To feed the rapidly growing world population in 2050, agricultural food production must be doubled using the same land resources footprint. At the same time, soil resources are threatened due to improper management and climate change. Despite the many important functions of soil, many fundamental knowledge gaps remain, regarding the role of soil biota and biodiversity on ecosystem services, the structure and dynamics of soil communities, the interplay between hydrologic and biotic processes, the quantification of soil biogeochemical processes and soil structural processes, the resilience and recovery of soils from stress, as well as the prediction of soil development and the evolution of soils in the landscape, to name a few. Soil models have long played an important role in quantifying and predicting soil processes and related ecosystem services. However, a new generation of soil models based on a whole systems approach comprising all physical, mechanical, chemical and biological processes is now required to address these critical knowledge gaps and thus contribute to the preservation of ecosystem services, improve our understanding of climate-change-feedback processes, bridge basic soil science research and management, and facilitate the communication between science and society. To meet these challenges an international community effort is required, similar to initiatives in systems biology, hydrology, and climate and crop research. Our consortium will bring together modelers and experimental soil scientists at the forefront of new technologies and approaches to characterize soils. By addressing these aims, the consortium will contribute to improve the role of soil modeling as a knowledge dissemination instrument in addressing key

  6. 34 CFR 614.4 - Which member of the consortium must act as the lead applicant and fiscal agent?

    Science.gov (United States)

    2010-07-01

    ... TEACHERS TO USE TECHNOLOGY § 614.4 Which member of the consortium must act as the lead applicant and fiscal agent? (a) For purposes of 34 CFR 75.127, the lead applicant for the consortium must be a nonprofit member of the consortium. (b) The lead applicant must serve as the fiscal agent. (Authority: 20...

  7. Effectiveness of Endophytic Bacterial Consortium of Coffee Plant on Mortality of Pratylenchus Coffeae in Vitro

    OpenAIRE

    dwi halimah; Abdul Munif; Giyanto Giyanto

    2015-01-01

    Bacteria live in wild in form of a consortium. Use of microbial consortium tends to give better results than single isolate, because the action of enzyme of each type of microbe can complement each other in order to survive. This study aimed to study the effectiveness of bacterial endophytic consortium from coffee plant on plant growth and mortality of parasitic nematodes in coffee. Isolation of bacteria is conducted  by growing the crushed roots, stems and leaves of coffee on 20% TSA media, ...

  8. Fiscal 1998 achievement report on regional consortium research and development project. Venture business fostering regional consortium in its 2nd year--Creation of key industries (Development of manufacturing system for multiple applications of biological resources); 1998 nendo yuyo seibutsu shigen no tamokuteki riyo no tame no kako seizo system no kenkyu kaihatsu seika hokokusho. 2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Research and development is conducted to collect intermediate products from Okinawan herbs for the production of antioxidant products usable for various purposes. Substance-producing plants are screened and the substances they offer are assessed for antioxidant activity, extracted, processed, prepared for market, and checked for safety. At the Okinawa Industrial Technology Center, a DPPH (1,1-diphenyl-2-picrylhydrazyl)/microplate method has been established, which promptly measures the antioxidant activity of the substances. Using this technology, the divisions concerned of industrial, academic, and governmental organizations cooperate with each other over the optimization of herb cultivation technology, development of a herbal ingredient analyzing technology, efficacy of herbs, development of a safety assessment system, development of a technology for the effective extraction, processing, and preparation of herbal ingredients, and the development of a technology of assessing antioxidant intermediate products for their efficacy. As the result, a technology is established of producing intermediate antioxidant products from Guava, Ryukyuyomogi, and Ukonisomatsu. They are unique Okinawan products, and sell at 40,000-50,000 yen. Since the prices are equal to or lower than the prices of other antioxidant intermediate products, probabilities are very high that they will get into markets in Japan proper. (NEDO)

  9. Bioremediation of textile azo dyes by aerobic bacterial consortium.

    Science.gov (United States)

    Senan, Resmi C; Abraham, T Emilia

    2004-08-01

    An aerobic bacterial consortium consisting of two isolated strains (BF1, BF2) and a strain of Pseudomonas putida (MTCC1194) was developed for the aerobic degradation of a mixture of textile azodyes and individual azodyes at alkaline pH (9-10.5) and salinity (0.9-3.68 g/l) at ambient temperature (28 +/- 2 degrees C). The degradation efficiency of the strains in different media (mineral media and in the Simulated textile effluent (STE)) and at different dye concentrations were studied. The presence of a H2O2 independent oxidase-laccase (26.5 IU/ml) was found in the culture filtrate of the organism BF2. The analysis of the degraded products by TLC and HPLC, after the microbial treatment of the dyes showed the absence of amines and the presence of low molecular weight oxidative degradation products. The enzymes present in the crude supernatant was found to be reusable for the dye degradation.

  10. Advances in Metal Supported Cells in the METSOFC EU Consortium

    DEFF Research Database (Denmark)

    McKenna, B. J.; Christiansen, N.; Schauperl, R.;

    2013-01-01

    The EU‐sponsored project “METSOFC”, completed at the end of 2011, resulted in a number of advancements toward implementing a mechanically robust metal support as the structural element in SOFC. Technical University of Denmark (DTU) Energy Conversion's research into planar metal supported cells (M......, and tolerance to thermal cycles and load cycles. These and other key outcomes of the METSOFC consortium are covered, along with associated work supported by the Danish National Advanced Technology Foundation.......The EU‐sponsored project “METSOFC”, completed at the end of 2011, resulted in a number of advancements toward implementing a mechanically robust metal support as the structural element in SOFC. Technical University of Denmark (DTU) Energy Conversion's research into planar metal supported cells...... (MSCs) has produced an advanced cell design with high performance and mechanical robustness. At low operation temperatures (650 °C), these cells have shown low Area‐specific resistances (ASRs): 0.35 Ω cm2 in cell tests (16 cm2 active area) and under 0.3 Ω cm2 in button cells (0.5 cm2 active area...

  11. Consortium analysis of 7 candidate SNPs for ovarian cancer

    DEFF Research Database (Denmark)

    Ramus, S.J.; Vierkant, R.A.; Johnatty, S.E.;

    2008-01-01

    The Ovarian Cancer Association Consortium selected 7 candidate single nucleotide polymorphisms (SNPs), for which there is evidence from previous studies of an association with variation in ovarian cancer or breast cancer risks. The SNPs selected for analysis were F31I (rs2273535) in AURKA, N372H...... was suggestive although no longer statistically significant (ordinal OR 0.92, 95% CI 0.79-1.06). This SNP has also been shown to have an association with decreased risk in breast cancer. There was a suggestion of an association for AURKA, when one study that caused significant study heterogeneity was excluded...... [ordinal OR 1.10 (95% CI 1.01-1.20) p = 0.027; dominant OR 1.12 (95% CI 1.01-1.24) p = 0.03]. The other 5 SNPs in BRCA2, CDKN2A, SRD5A2, CASP8 and TGFB1 showed no association with ovarian cancer risk; given the large sample size, these results can also be considered to be informative. These null results...

  12. Dedicated Beamline Facilities for Catalytic Research. Synchrotron Catalysis Consortium (SCC)

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Jingguang [Columbia Univ., New York, NY; Frenkel, Anatoly [Yeshiva Univ., New York, NY (United States); Rodriguez, Jose [Brookhaven National Lab. (BNL), Upton, NY (United States); Adzic, Radoslav [Brookhaven National Lab. (BNL), Upton, NY (United States); Bare, Simon R. [UOP LLC, Des Plaines, IL (United States); Hulbert, Steve L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Karim, Ayman [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mullins, David R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Overbury, Steve [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-03-04

    Synchrotron spectroscopies offer unique advantages over conventional techniques, including higher detection sensitivity and molecular specificity, faster detection rate, and more in-depth information regarding the structural, electronic and catalytic properties under in-situ reaction conditions. Despite these advantages, synchrotron techniques are often underutilized or unexplored by the catalysis community due to various perceived and real barriers, which will be addressed in the current proposal. Since its establishment in 2005, the Synchrotron Catalysis Consortium (SCC) has coordinated significant efforts to promote the utilization of cutting-edge catalytic research under in-situ conditions. The purpose of the current renewal proposal is aimed to provide assistance, and to develop new sciences/techniques, for the catalysis community through the following concerted efforts: Coordinating the implementation of a suite of beamlines for catalysis studies at the new NSLS-II synchrotron source; Providing assistance and coordination for catalysis users at an SSRL catalysis beamline during the initial period of NSLS to NSLS II transition; Designing in-situ reactors for a variety of catalytic and electrocatalytic studies; Assisting experimental set-up and data analysis by a dedicated research scientist; Offering training courses and help sessions by the PIs and co-PIs.

  13. SUNrises on the International Plant Nucleus Consortium: SEB Salzburg 2012.

    Science.gov (United States)

    Graumann, Katja; Bass, Hank W; Parry, Geraint

    2013-01-01

    The nuclear periphery is a dynamic, structured environment, whose precise functions are essential for global processes-from nuclear, to cellular, to organismal. Its main components-the nuclear envelope (NE) with inner and outer nuclear membranes (INM and ONM), nuclear pore complexes (NPC), associated cytoskeletal and nucleoskeletal components as well as chromatin are conserved across eukaryotes (Fig. 1). In metazoans in particular, the structure and functions of nuclear periphery components are intensely researched partly because of their involvement in various human diseases. While far less is known about these in plants, the last few years have seen a significant increase in research activity in this area. Plant biologists are not only catching up with the animal field, but recent findings are pushing our advances in this field globally. In recognition of this developing field, the Annual Society of Experimental Biology Meeting in Salzburg kindly hosted a session co-organized by Katja Graumann and David E. Evans (Oxford Brookes University) highlighting new insights into plant nuclear envelope proteins and their interactions. This session brought together leading researchers with expertise in topics such as epigenetics, meiosis, nuclear pore structure and functions, nucleoskeleton and nuclear envelope composition. An open and friendly exchange of ideas was fundamental to the success of the meeting, which resulted in founding the International Plant Nucleus Consortium. This review highlights new developments in plant nuclear envelope research presented at the conference and their importance for the wider understanding of metazoan, yeast and plant nuclear envelope functions and properties.

  14. Methyltert-butyl Ether (MTBE Degradation by a Microbial Consortium

    Directory of Open Access Journals (Sweden)

    S. B. Mortazavi

    2005-01-01

    Full Text Available Methyl tert-butyl ether (MTBE is added to reformulated gasoline to meet the 1990 Clean Air Act directives. Widespread use of MTBE in gasoline has resulted in groundwater contamination. Because of its undesirable effects on drinking water and ecologically harmful effects, MTBE removal has become a public health and environmental concern. In this study, we have isolated a mixed bacterial culture which is capable of degrading the MTBE as a sole carbon and energy source. This consortium was developed from mixed urban and petrochemical activated sludge after 4 month's enrichment. Enrichment was conducted in batch reactor, fitted with a screw cap and butyl rubber septum. MTBE concentration was measured in head space by gas chromatography. Degradation was determined by MTBE removal. MTBE biodegradation was depended to Dissolved Oxygen (DO concentration and not affected by the changes in concentration of trace element solution or other stimulator Substances. Degradation rates were nearly 1.478 mg MTBE h-1 g-1 (wet biomass and didn't change with MTBE concentration (up 500 mg L-1.

  15. Photocatalytic Removal of Microbiological Consortium and Organic Matter in Greywater

    Directory of Open Access Journals (Sweden)

    Nazmiye Cemre Birben

    2016-06-01

    Full Text Available This study aimed to investigate TiO2 photocatalytic degradation of synthetically-prepared greywater samples with differing compositional contents of organic matter (OM, anion concentration, and microbiological consortium. Treatment efficiency was followed through removal of organic matter content in terms of dissolved organic carbon (DOC, specific spectroscopic parameters, and bacterial inactivation. Photocatalytic degradation kinetics were expressed by pseudo first-order kinetic modeling. The best DOC removal rates were attained for greywater samples containing OM with lower molecular size fractions. In addition, either enhancing or reducing the effect of common anions as radical scavengers were observed depending on the composition and concentration of variables in the greywater matrix. Moreover, possibility of a photocatalytic disinfection process was found to be of a bacteria type specific in OM-loaded synthetic greywater samples. Photocatalytic destruction of fecal streptococci required longer irradiation periods under all conditions. Bacterial removal rates were found to be in the order of total coliform > fecal coliform > fecal streptococci, for low organic load greywater, and fecal coliform > total coliform > fecal streptococci, for high organic load greywater.

  16. The Tennessee Mouse Genome Consortium: Identification of ocular mutants

    Energy Technology Data Exchange (ETDEWEB)

    Jablonski, Monica M. [University of Tennessee Health Science Center, Memphis; Wang, Xiaofei [ORNL; Lu, Lu [University of Tennessee Health Science Center, Memphis; Miller, Darla R [ORNL; Rinchik, Eugene M [ORNL; Williams, Robert [University of Tennessee Health Science Center, Memphis; Goldowitz, Daniel [University of Tennessee Health Science Center, Memphis

    2005-06-01

    The Tennessee Mouse Genome Consortium (TMGC) is in its fifth year of a ethylnitrosourea (ENU)-based mutagenesis screen to detect recessive mutations that affect the eye and brain. Each pedigree is tested by various phenotyping domains including the eye, neurohistology, behavior, aging, ethanol, drug, social behavior, auditory, and epilepsy domains. The utilization of a highly efficient breeding protocol and coordination of various universities across Tennessee makes it possible for mice with ENU-induced mutations to be evaluated by nine distinct phenotyping domains within this large-scale project known as the TMGC. Our goal is to create mutant lines that model human diseases and disease syndromes and to make the mutant mice available to the scientific research community. Within the eye domain, mice are screened for anterior and posterior segment abnormalities using slit-lamp biomicroscopy, indirect ophthalmoscopy, fundus photography, eye weight, histology, and immunohistochemistry. As of January 2005, we have screened 958 pedigrees and 4800 mice, excluding those used in mapping studies. We have thus far identified seven pedigrees with primary ocular abnormalities. Six of the mutant pedigrees have retinal or subretinal aberrations, while the remaining pedigree presents with an abnormal eye size. Continued characterization of these mutant mice should in most cases lead to the identification of the mutated gene, as well as provide insight into the function of each gene. Mice from each of these pedigrees of mutant mice are available for distribution to researchers for independent study.

  17. The National Astronomy Consortium - An Adaptable Model for OAD?

    Science.gov (United States)

    Sheth, Kartik

    2015-08-01

    The National Astronomy Consortium (NAC) is a program led by the National Radio Astronomy Observatory (NRAO) and Associated Universities Inc., (AUI) in partnership with the National Society of Black Physicists (NSBP), and a number of minority and majority universities to increase the numbers of students from underrepresented groups and those otherwise overlooked by the traditional academic pipeline into STEM or STEM-related careers. The seed for the NAC was a partnership between NRAO and Howard University which began with an exchange of a few summer students five years ago. Since then the NAC has grown tremendously. Today the NAC aims to host between 4 to 5 cohorts nationally in an innovative model in which the students are mentored throughout the year with multiple mentors and peer mentoring, continued engagement in research and professional development / career training throughout the academic year and throughout their careers.The NAC model has already shown success and is a very promising and innovative model for increasing participation of young people in STEM and STEM-related careers. I will discuss how this model could be adapted in various countries at all levels of education.

  18. 2006 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Lewis County, WA

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Watershed Sciences, Inc. collected Light Detection and Ranging (LiDAR) data of Western Lewis County for the Puget Sound LiDAR Consortium. This data set covers...

  19. Communal microaerophilic-aerobic biodegradation of Amaranth by novel NAR-2 bacterial consortium.

    Science.gov (United States)

    Chan, Giek Far; Rashid, Noor Aini Abdul; Chua, Lee Suan; Ab llah, Norzarini; Nasiri, Rozita; Ikubar, Mohamed Roslan Mohamad

    2012-02-01

    A novel bacterial consortium, NAR-2 which consists of Citrobacter freundii A1, Enterococcus casseliflavus C1 and Enterobacter cloacae L17 was investigated for biodegradation of Amaranth azo dye under sequential microaerophilic-aerobic condition. The NAR-2 bacterial consortium with E. casseliflavus C1 as the dominant strain enhanced the decolorization process resulting in reduction of Amaranth in 30 min. Further aerobic biodegradation, which was dominated by C. freundii A1 and E. cloacae L17, allowed biotransformation of azo reduction intermediates and mineralization via metabolic pathways including benzoyl-CoA, protocatechuate, salicylate, gentisate, catechol and cinnamic acid. The presence of autoxidation products which could be metabolized to 2-oxopentenoate was elucidated. The biodegradation mechanism of Amaranth by NAR-2 bacterial consortium was predicted to follow the steps of azo reduction, deamination, desulfonation and aromatic ring cleavage. This is for the first time the comprehensive microaerophilic-aerobic biotransformation pathways of Amaranth dye intermediates by bacterial consortium are being proposed.

  20. 2015 Puget Sound LiDAR Consortium (PSLC) LiDAR: WA DNR Lands (P2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In June 2014, WSI, a Quantum Spatial Inc. (QSI) company, was contracted by the Puget Sound LiDAR Consortium (PSLC) to collect Light Detection and Ranging (LiDAR)...

  1. 2015 Puget Sound LiDAR Consortium (PSLC) LiDAR: WA DNR Lands (P1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In June 2014, WSI, a Quantum Spatial Inc. (QSI) company, was contracted by the Puget Sound LiDAR Consortium (PSLC) to collect Light Detection and Ranging (LiDAR)...

  2. 2013 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Tulalip Partnership

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In October 2012, WSI (Watershed Sciences, Inc.) was contracted by the Puget Sound LiDAR Consortium (PSLC)to collect Light Detection and Ranging (LiDAR) data on a...

  3. 2013 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Nooksack

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In July 2012, WSI (Watershed Sciences, Inc.) was contracted by the Puget Sound LiDAR Consortium (PSLC) to collect Light Detection and Ranging (LiDAR) data on a...

  4. 2003 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Yakima County, Washington

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TerraPoint surveyed and created this data for the Puget Sound LiDAR Consortium under contract. The area surveyed is approximately 77 square miles and covers a...

  5. 2003 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Snohomish County, Washington

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TerraPoint surveyed and created this data for the Puget Sound LiDAR Consortium under contract. The area surveyed is approximately 167 square miles and covers a...

  6. 2013 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Saddle Mountain

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In October 2013, WSI, a Quantum Spatial Company (QSI), was contracted by the Puget Sound LiDAR Consortium (PSLC) to collect Light Detection and Ranging (LiDAR) data...

  7. 2000 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Kitsap Peninsula, Washington

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TerraPoint surveyed and created this data for the Puget Sound LiDAR Consortium under contract. The area surveyed is approximately 1,146 square miles and covers part...

  8. Clinical-histological associations in gastroparesis : results from the Gastroparesis Clinical Research Consortium

    NARCIS (Netherlands)

    Grover, M.; Bernard, C. E.; Pasricha, P. J.; Lurken, M. S.; Faussone-Pellegrini, M. S.; Smyrk, T. C.; Parkman, H. P.; Abell, T. L.; Snape, W. J.; Hasler, W. L.; Mccallum, R. W.; Nguyen, L.; Koch, K. L.; Calles, J.; Lee, L.; Tonascia, J.; Uenalp-Arida, A.; Hamilton, F. A.; Farrugia, G.

    2012-01-01

    Background Cellular changes associated with diabetic (DG) and idiopathic gastroparesis (IG) have recently been described from patients enrolled in the Gastroparesis Clinical Research Consortium. The association of these cellular changes with gastroparesis symptoms and gastric emptying is unknown. Th

  9. 2014 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Willapa Valley (Delivery 1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In January, 2014 WSI, a Quantum Spatial (QSI) company, was contracted by the Puget Sound LiDAR Consortium (PSLC) to collect Light Detection and Ranging (LiDAR) data...

  10. 2009 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Lewis County, Washington

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Watershed Sciences, Inc. (WSI) collected Light Detection and Ranging (LiDAR) data for the Lewis County survey area for the Puget Sound LiDAR Consortium. This data...

  11. The FaceBase Consortium: A comprehensive program to facilitate craniofacial research

    OpenAIRE

    Hochheiser, Harry; Aronow, Bruce J.; Artinger, Kristin; Beaty, Terri H.; Brinkley, James F.; Chai, Yang; Clouthier, David; Cunningham, Michael L.; Dixon, Michael; Donahue, Leah Rae; Fraser, Scott E.; Hallgrimsson, Benedikt; Iwata, Junichi; Klein, Ophir; Marazita, Mary L.

    2011-01-01

    The FaceBase Consortium consists of ten interlinked research and technology projects whose goal is to generate craniofacial research data and technology for use by the research community through a central data management and integrated bioinformatics hub. Funded by the National Institute of Dental and Craniofacial Research (NIDCR) and currently focused on studying the development of the middle region of the face, the Consortium will produce comprehensive datasets of global gene expression pat...

  12. Potential Bacterial Consortium to Increase the Effectiveness of Beer Wastewater Treatment

    OpenAIRE

    Putu Nia Anggraeni; Ida Bagus Wayan Gunam; Retno Kawuri

    2014-01-01

    The main objective of this research is to determine the effectiveness of microbial consortia in beer wastewater treatment. The research was initiated with the isolation of soil microbial consortium that has been contaminated by beer waste water, followed by the selection of the best potential microbial beer wastewater treatment. At the end, the selection of the best microbial consortium was tested in beer wastewater treatment based on pollutant parameters namely biochemical oxygen demand (BOD...

  13. Highly migratory shark fisheries research by the National Shark Research Consortium (NSRC), 2002-2007

    OpenAIRE

    Robert E Hueter; Cailliet, Gregor M.; Ebert, David A.; Musick, John A.; Burgess, George H.

    2007-01-01

    The National Shark Research Consortium (NSRC) includes the Center for Shark Research at Mote Marine Laboratory, the Pacific Shark Research Center at Moss Landing Marine Laboratories, the Shark Research Program at the Virginia Institute of Marine Science, and the Florida Program for Shark Research at the University of Florida. The consortium objectives include shark-related research in the Gulf of Mexico and along the Atlantic and Pacific coasts of the U.S., education and scientific cooperation.

  14. Washoe Tribe Nevada Inter-Tribal Energy Consortium Energy Organization Enhancement Project Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Jennifer [Washoe Tribe of NV and Ca

    2014-11-06

    The Washoe Tribe of Nevada and California was awarded funding from the Department of Energy to complete the Nevada Inter-Tribal Energy Consortium Energy Organization Enhancement Project. The main goal of the project was to enhance the capacity of the Nevada Inter-Tribal Energy Consortium (NITEC) to effectively assist tribes within Nevada to technically manage tribal energy resources and implement tribal energy projects.

  15. The Pharmaceutical Industry Beamline of Pharmaceutical Consortium for Protein Structure Analysis

    International Nuclear Information System (INIS)

    The Pharmaceutical Industry Beamline was constructed by the Pharmaceutical Consortium for Protein Structure Analysis which was established in April 2001. The consortium is composed of 22 pharmaceutical companies affiliating with the Japan Pharmaceutical Manufacturers Association. The beamline is the first exclusive on that is owned by pharmaceutical enterprises at SPring-8. The specification and equipments of the Pharmaceutical Industry Beamline is almost same as that of RIKEN Structural Genomics Beamline I and II. (author)

  16. Soybean after the consortium corn with tropical forages in the savannah

    OpenAIRE

    Cássia Maria de Paula Garcia; Marcelo Andreotti; Marcelo Carvalho Minhoto Teixeira Filho; Keny Samejima Mascarenha Lopes; Ciniro Costa; Erikelly Aline Ribeiro de Santana

    2013-01-01

    The biggest limitation to sustainable tillage in the Savannah region is the low biomass accumulation during autumn up to spring, due to low water availability and high temperatures characterizing these regions as having a warm and dry winter. The consortium of grains crops with tropical forages mainly of the genus Panicum and Urochloa is an alternative, to this situation. This study aimed to evaluate the effect of the straw production of Panicum and Urochloa after consortium with corn in the ...

  17. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

    OpenAIRE

    Freschi, Luca; Jeukens, Julie; Kukavica-Ibrulj, Irena; Boyle, Brian; Dupont, Marie-Josée; Laroche, Jérôme; Larose, Stéphane; Maaroufi, Halim; Fothergill, Joanne L.; Moore, Matthew; Winsor, Geoffrey L.; Shawn D Aaron; Barbeau, Jean; Bell, Scott C.; Burns, Jane L.

    2015-01-01

    The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are available through the International Pseudomonas Consortium Database (http://ipcd.ibis.ulaval.ca/). Here, we present our strategy and the results that emerged from the analysis of the first 389 genomes....

  18. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

    OpenAIRE

    Luca eFreschi; Julie eJeukens; Irena eKukavica-Ibrulj; Brian eBoyle; Marie-Josée eDupont; Jérôme eLaroche; Stéphane eLarose; Halim eMaaroufi; Fothergill, Joanne L.; Matthew eMoore; Winsor, Geoffrey L.; Shawn D Aaron; Jean eBarbeau; Bell, Scott C.; Burns, Jane L.

    2015-01-01

    The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are available through the International Pseudomonas Consortium Database (http://ipcd.ibis.ulaval.ca/). Here, we present our strategy and the results that emerged from the analysis of the first 389 genomes....

  19. The Pharmaceutical Industry Beamline of Pharmaceutical Consortium for Protein Structure Analysis

    CERN Document Server

    Nishijima, K

    2002-01-01

    The Pharmaceutical Industry Beamline was constructed by the Pharmaceutical Consortium for Protein Structure Analysis which was established in April 2001. The consortium is composed of 22 pharmaceutical companies affiliating with the Japan Pharmaceutical Manufacturers Association. The beamline is the first exclusive on that is owned by pharmaceutical enterprises at SPring-8. The specification and equipments of the Pharmaceutical Industry Beamline is almost same as that of RIKEN Structural Genomics Beamline I and II. (author)

  20. Oil Production by a Consortium of Oleaginous Microorganisms grown on primary effluent wastewater

    Energy Technology Data Exchange (ETDEWEB)

    Hall, Jacqueline; Hetrick, Mary; French, Todd; Hernandez, Rafael; Donaldson, Janet; Mondala, Andro; Holmes, William

    2011-01-01

    Municipal wastewater could be a potential growth medium that has not been considered for cultivating oleaginous microorganisms. This study is designed to determine if a consortium of oleaginous microorganism can successfully compete for carbon and other nutrients with the indigenous microorganisms contained in primary effluent wastewater. RESULTS: The oleaginous consortium inoculated with indigenous microorganisms reached stationary phase within 24 h, reaching a maximum cell concentration of 0.58 g L -1. Water quality post-oleaginous consortium growth reached a maximum chemical oxygen demand (COD) reduction of approximately 81%, supporting the consumption of the glucose within 8 h. The oleaginous consortium increased the amount of oil produced per gram by 13% compared with indigenous microorganisms in raw wastewater. Quantitative polymerase chain reaction (qPCR) results show a substantial population increase in bacteria within the first 24 h when the consortium is inoculated into raw wastewater. This result, along with the fatty acid methyl esters (FAMEs) results, suggests that conditions tested were not sufficient for the oleaginous consortium to compete with the indigenous microorganisms.

  1. Biostimulation of metal-resistant microbial consortium to remove zinc from contaminated environments.

    Science.gov (United States)

    Mejias Carpio, Isis E; Franco, Diego Castillo; Zanoli Sato, Maria Inês; Sakata, Solange; Pellizari, Vivian H; Seckler Ferreira Filho, Sidney; Frigi Rodrigues, Debora

    2016-04-15

    Understanding the diversity and metal removal ability of microorganisms associated to contaminated aquatic environments is essential to develop metal remediation technologies in engineered environments. This study investigates through 16S rRNA deep sequencing the composition of a biostimulated microbial consortium obtained from the polluted Tietê River in São Paulo, Brazil. The bacterial diversity of the biostimulated consortium obtained from the contaminated water and sediment was compared to the original sample. The results of the comparative sequencing analyses showed that the biostimulated consortium and the natural environment had γ-Proteobacteria, Firmicutes, and uncultured bacteria as the major classes of microorganisms. The consortium optimum zinc removal capacity, evaluated in batch experiments, was achieved at pH=5 with equilibrium contact time of 120min, and a higher Zn-biomass affinity (KF=1.81) than most pure cultures previously investigated. Analysis of the functional groups found in the consortium demonstrated that amine, carboxyl, hydroxyl, and phosphate groups present in the consortium cells were responsible for zinc uptake. PMID:26849331

  2. Results From the John Glenn Biomedical Engineering Consortium. A Success Story for NASA and Northeast Ohio

    Science.gov (United States)

    Nall, Marsha M.; Barna, Gerald J.

    2009-01-01

    The John Glenn Biomedical Engineering Consortium was established by NASA in 2002 to formulate and implement an integrated, interdisciplinary research program to address risks faced by astronauts during long-duration space missions. The consortium is comprised of a preeminent team of Northeast Ohio institutions that include Case Western Reserve University, the Cleveland Clinic, University Hospitals Case Medical Center, The National Center for Space Exploration Research, and the NASA Glenn Research Center. The John Glenn Biomedical Engineering Consortium research is focused on fluid physics and sensor technology that addresses the critical risks to crew health, safety, and performance. Effectively utilizing the unique skills, capabilities and facilities of the consortium members is also of prime importance. Research efforts were initiated with a general call for proposals to the consortium members. The top proposals were selected for funding through a rigorous, peer review process. The review included participation from NASA's Johnson Space Center, which has programmatic responsibility for NASA's Human Research Program. The projects range in scope from delivery of prototype hardware to applied research that enables future development of advanced technology devices. All of the projects selected for funding have been completed and the results are summarized. Because of the success of the consortium, the member institutions have extended the original agreement to continue this highly effective research collaboration through 2011.

  3. Biodegradation mechanisms and kinetics of azo dye 4BS by a microbial consortium.

    Science.gov (United States)

    He, Fang; Hu, Wenrong; Li, Yuezhong

    2004-10-01

    A microbial consortium consisting of a white-rot fungus 8-4* and a Pseudomonas 1-10 was isolated from wastewater treatment facilities of a local dyeing house by enrichment, using azo dye Direct Fast Scarlet 4BS as the sole source of carbon and energy, which had a high capacity for rapid decolorization of 4BS. To elucidate the decolorization mechanisms, decolorization of 4BS was compared between individual strains and the microbial consortium under different treatment processes. The microbial consortium showed a significant improvement on dye decolorization rates under either static or shaking culture, which might be attributed to the synergetic reaction of single strains. From the curve of COD values and the UV-visible spectra of 4BS solutions before and after decolorization cultivation with the microbial consortium, it was found that 4BS could be mineralized completely, and the results had been used for presuming the degrading pathway of 4BS. This study also examined the kinetics of 4BS decolorization by immobilized microbial consortium. The results demonstrated that the optimal decolorization activity was observed in pH range between four and 9, temperature range between 20 and 40 degrees C and the maximal specific decolorization rate occurred at 1,000 mg l(-1) of 4BS. The proliferation and distribution of microbial consortium were also microscopically observed, which further confirmed the decolorization mechanisms of 4BS.

  4. Development of Leptospirillum ferriphilum dominated consortium for ferric iron regeneration and metal bioleaching under extreme stresses.

    Science.gov (United States)

    Patel, Bhargav C; Tipre, Devayani R; Dave, Shailesh R

    2012-08-01

    Activated iron oxidizing consortium SR-BH-L enriched from Rajpardi lignite mine soil sample gave iron oxidation rate 1954 mg/L/h. Developed novel polystress resistant consortium oxidized ferrous iron under 11cP viscosity, 7.47 M ionic strength, 2.3 pH and g/L of 0.50 cadmium, 3.75 copper, 0.20 lead, 92.00 zinc, 6.4 sodium, 5.5 chloride, 154 sulphate and 393.8 TDS. The developed consortium showed 78.0% and 70.0% copper and zinc extraction from polymetallic bulk concentrate in monophasic bioleaching process. The bioregenerated ferric by the consortium in leachate showed 80.81% and 54.0% copper and zinc leaching in only 30 and 90 min. The DGGE analysis indicated the presence of 11 OTUs in the consortium. 16S rRNA gene sequence (JN797729) of the dominant band on DGGE shared >99% similarity with Leptospirillum ferriphilum. RE digestion analysis of the total 16S rRNA gene also illustrated the dominance of L. ferriphilum in the consortium. PMID:22717567

  5. Thirty Years of Innovation in Seismology with the IRIS Consortium

    Science.gov (United States)

    Sumy, D. F.; Woodward, R.; Aderhold, K.; Ahern, T. K.; Anderson, K. R.; Busby, R.; Detrick, R. S.; Evers, B.; Frassetto, A.; Hafner, K.; Simpson, D. W.; Sweet, J. R.; Taber, J.

    2015-12-01

    The United States academic seismology community, through the National Science Foundation (NSF)-funded Incorporated Research Institutions for Seismology (IRIS) Consortium, has promoted and encouraged a rich environment of innovation and experimentation in areas such as seismic instrumentation, data processing and analysis, teaching and curriculum development, and academic science. As the science continually evolves, IRIS helps drive the market for new research tools that enable science by establishing a variety of standards and goals. This has often involved working directly with manufacturers to better define the technology required, co-funding key development work or early production prototypes, and purchasing initial production runs. IRIS activities have helped establish de-facto international standards and impacted the commercial sector in areas such as seismic instrumentation, open-access data management, and professional development. Key institutional practices, conducted and refined over IRIS' thirty-year history of operations, have focused on open-access data availability, full retention of maximum-bandwidth, continuous data, and direct community access to state-of-the-art seismological instrumentation and software. These practices have helped to cultivate and support a thriving commercial ecosystem, and have been a key element in the professional development of multiple generations of seismologists who now work in both industry and academia. Looking toward the future, IRIS is increasing its engagement with industry to better enable bi-directional exchange of techniques and technology, and enhancing the development of tomorrow's workforce. In this presentation, we will illustrate how IRIS has promoted innovations grown out of the academic community and spurred technological advances in both academia and industry.

  6. Computerized comprehensive data analysis of Lung Imaging Database Consortium (LIDC)

    International Nuclear Information System (INIS)

    Purpose: Lung Image Database Consortium (LIDC) is the largest public CT image database of lung nodules. In this study, the authors present a comprehensive and the most updated analysis of this dynamically growing database under the help of a computerized tool, aiming to assist researchers to optimally use this database for lung cancer related investigations. Methods: The authors developed a computer scheme to automatically match the nodule outlines marked manually by radiologists on CT images. A large variety of characteristics regarding the annotated nodules in the database including volume, spiculation level, elongation, interobserver variability, as well as the intersection of delineated nodule voxels and overlapping ratio between the same nodules marked by different radiologists are automatically calculated and summarized. The scheme was applied to analyze all 157 examinations with complete annotation data currently available in LIDC dataset. Results: The scheme summarizes the statistical distributions of the abovementioned geometric and diagnosis features. Among the 391 nodules, (1) 365 (93.35%) have principal axis length ≤20 mm; (2) 120, 75, 76, and 120 were marked by one, two, three, and four radiologists, respectively; and (3) 122 (32.48%) have the maximum volume overlapping ratios ≥80% for the delineations of two radiologists, while 198 (50.64%) have the maximum volume overlapping ratios <60%. The results also showed that 72.89% of the nodules were assessed with malignancy score between 2 and 4, and only 7.93% of these nodules were considered as severely malignant (malignancy ≥4). Conclusions: This study demonstrates that LIDC contains examinations covering a diverse distribution of nodule characteristics and it can be a useful resource to assess the performance of the nodule detection and/or segmentation schemes.

  7. Microbial hydrogen production from sewage sludge bioaugmented with a constructed microbial consortium

    Energy Technology Data Exchange (ETDEWEB)

    Kotay, Shireen Meher; Das, Debabrata [Department of Biotechnology, Indian Institute of Technology, Kharagpur 721302 (India)

    2010-10-15

    A constructed microbial consortium was formulated from three facultative H{sub 2}-producing anaerobic bacteria, Enterobacter cloacae IIT-BT 08, Citrobacter freundii IIT-BT L139 and Bacillus coagulans IIT-BT S1. This consortium was tested as the seed culture for H{sub 2} production. In the initial studies with defined medium (MYG), E. cloacae produced more H{sub 2} than the other two strains and it also was found to be the dominant member when consortium was used. On the other hand, B. coagulans as a pure culture gave better H{sub 2} yield (37.16 ml H{sub 2}/g COD{sub consumed}) than the other two strains using sewage sludge as substrate. The pretreatment of sludge included sterilization (15% v/v), dilution and supplementation with 0.5% w/v glucose, which was found to be essential to screen out the H{sub 2} consuming bacteria and ameliorate the H{sub 2} production. Considering (1:1:1) defined consortium as inoculum, COD reduction was higher and yield of H{sub 2} was recorded to be 41.23 ml H{sub 2}/g COD{sub reduced}. Microbial profiling of the spent sludge showed that B. coagulans was the dominant member in the constructed consortium contributing towards H{sub 2} production. Increase in H{sub 2} yield indicated that in consortium, the substrate utilization was significantly higher. The H{sub 2} yield from pretreated sludge (35.54 ml H{sub 2}/g sludge) was comparatively higher than that reported in literature (8.1-16.9 ml H{sub 2}/g sludge). Employing formulated microbial consortium for biohydrogen production is a successful attempt to augment the H{sub 2} yield from sewage sludge. (author)

  8. Study of a plugging microbial consortium using crude oil as sole carbon source

    Institute of Scientific and Technical Information of China (English)

    Wang Jing; Yan Guiwen; An Mingquan; Liu Jieli; Zhang Houming; Chen Yun

    2008-01-01

    A microbial consortium named Y4 capable of producing biopolymers was isolated from petroleum-contaminated soil in the Dagang Oilfield, China. It includes four bacterial strains: Y4-1 (Paenibacillus sp.), Y4-2 (Actinomadura sp.), Y4-3 (Uncultured bacterium clone) and Y4-4 (Brevibacillus sp.). The optimal conditions for the growth of the consortium Y4 were as follows: temperature about 46 ℃,pH about 7.0 and salinity about 20.0 g/L. The major metabolites were analyzed with gas chromatographymass spectrometry (GC-MS). A comparison was made between individual strains and the microbial consortium for biopolymer production in different treatment processes. The experimental results showed that the microbial consortium Y4 could produce more biopolymers than individual strains, and the reason might be attributed to the synergetic action of strains. The biopolymers were observed with optical and electron microscopes and analyzed by paper chromatography. It was found that the biopolymers produced by the microbial consortium Y4 were insoluble in water and were of reticular structure, and it was concluded that the biopolymers were cellulose. Through a series of simulation experiments with sand cores, it was found that the microbial consortium Y4 could reduce the permeability of reservoir beds, and improve the efficiency of water flooding by growing biomass and producing biopolymers.The oil recovery was enhanced by 3.5% on average. The results indicated that the consortium Y4 could be used in microbial enhanced oil recovery and play an important role in bioremediation of oil polluted environments.

  9. The Historically Black Colleges and Universities/Minority Institutions Environmental Technology Consortium annual report, 1991--1992

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-12-31

    The member institutions of the Consortium continue to play a significant role in increasing the number of African Americans who enter the environmental professions through the implementation of the Consortium`s RETT Plan for Research, Education, and Technology Transfer. The four major program areas identified in the RETT Plan are as follows: (1) minority outreach and precollege education; (2) undergraduate education and postsecondary training; (3) graduate and postgraduate education and research; and (4) technology transfer.

  10. Innovations in Nuclear Infrastructure and Education From the SW Consortium

    International Nuclear Information System (INIS)

    This report describes the final expenditures for the INIE project during FY 08/09. (There were no expenditures during FY09/10 or during FY10/11.) To see the list of accomplishments done using the INIE funds, please see the reports included here. The last of the FY 07/08 funds were brought forward and used to complete two distance education modules teaching reactor experiments. These modules and parts from the modules are still being used and are being disseminated off-campus as a part of our distance education effort. The second largest expenditure was sending students to the ANS to present student papers on work that they had done the previous year underwritten by INIE funds. The remaining expenditures were IDC charges and minor travel expenses to give students a tour of a medical facility. Once again we wish to express of sincere appreciation of the INIE program and hope that the return on investment is appreciated by the DOE. Although INIE has come to a close, looking back at all the Consortium has accomplished is astounding. And, as was hoped, these funds have proved to be a springboard for continuing work, particularly at Texas A and M. With the resurgence of nuclear power, the utilities have realized that the nuclear workforce in the near future will be too small for the task of bringing dozens of new plants on line and have turned their attention to the URRs to help feed the workforce pipeline. The distance education modules developed at the A and M are soon to be broadcast throughout the country to help train a new generation of nuclear workers. Our students at the Nuclear Science Center at being snapped up by the nuclear power plants after graduating. Our research projects at A and M have all ended with new data, new ways of looking at old problems, and produced a covey of good students. I want to say 'Thanks' with utmost sincerity because without the INIE funds our efforts would yield a small fraction of the accomplishments you see in this report.

  11. Innovations in Nuclear Infrastructure and Education From the SW Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Warren Reece

    2011-03-22

    This report describes the final expenditures for the INIE project during FY 08/09. (There were no expenditures during FY09/10 or during FY10/11.) To see the list of accomplishments done using the INIE funds, please see the reports included here. The last of the FY 07/08 funds were brought forward and used to complete two distance education modules teaching reactor experiments. These modules and parts from the modules are still being used and are being disseminated off-campus as a part of our distance education effort. The second largest expenditure was sending students to the ANS to present student papers on work that they had done the previous year underwritten by INIE funds. The remaining expenditures were IDC charges and minor travel expenses to give students a tour of a medical facility. Once again we wish to express of sincere appreciation of the INIE program and hope that the return on investment is appreciated by the DOE. Although INIE has come to a close, looking back at all the Consortium has accomplished is astounding. And, as was hoped, these funds have proved to be a springboard for continuing work, particularly at Texas A&M. With the resurgence of nuclear power, the utilities have realized that the nuclear workforce in the near future will be too small for the task of bringing dozens of new plants on line and have turned their attention to the URRs to help feed the workforce pipeline. The distance education modules developed at the A&M are soon to be broadcast throughout the country to help train a new generation of nuclear workers. Our students at the Nuclear Science Center at being snapped up by the nuclear power plants after graduating. Our research projects at A&M have all ended with new data, new ways of looking at old problems, and produced a covey of good students. I want to say 'Thanks' with utmost sincerity because without the INIE funds our efforts would yield a small fraction of the accomplishments you see in this report.

  12. JV Task 120 - Coal Ash Resources Research Consortium Research

    Energy Technology Data Exchange (ETDEWEB)

    Debra Pflughoeft-Hassett; Loreal Heebink; David Hassett; Bruce Dockter; Kurt Eylands; Tera Buckley; Erick Zacher

    2009-03-28

    The Coal Ash Resources Research Consortium{reg_sign} (CARRC{reg_sign}, pronounced 'cars') is the core coal combustion product (CCP) research group at the Energy & Environmental Research Center (EERC). CARRC focuses on performing fundamental and applied scientific and engineering research emphasizing the environmentally safe, economical use of CCPs. CARRC member organizations, which include utilities and marketers, are key to developing industry-driven research in the area of CCP utilization and ensuring its successful application. The U.S. Department of Energy is a partner in CARRC through the EERC Jointly Sponsored Research Program, which provides matching funds for industrial member contributions and facilitates an increased level of effort in CARRC. CARRC tasks were designed to provide information on CCP performance, including environmental performance, engineering performance, favorable economics, and improved life cycle of products and projects. CARRC technical research tasks are developed based on member input and prioritization. CARRC special projects are developed with members and nonmembers to provide similar information and to support activities, including the assembly and interpretation of data, support for standards development and technology transfer, and facilitating product development and testing. CARRC activities from 2007 to 2009 included a range of research tasks, with primary work performed in laboratory tasks developed to answer specific questions or evaluate important fundamental properties of CCPs. The tasks were included in four categories: (1) Environmental Evaluations of CCPs; (2) Evaluation of Impacts on CCPs from Emission Controls; (3) Construction and Product-Related Activities; and (4) Technology Transfer and Maintenance Tasks. All tasks are designed to work toward achieving the CARRC overall goal and supporting objectives. The various tasks are coordinated in order to provide broad and useful technical data for CARRC members

  13. JV Task 6 - Coal Ash Resources Research Consortium Research

    Energy Technology Data Exchange (ETDEWEB)

    Debra Pflughoeft-Hassett; Tera Buckley; Bruce Dockter; Kurt Eylands; David Hassett; Loreal Heebink; Erick Zacher

    2008-04-01

    The Coal Ash Resources Research Consortium{reg_sign} (CARRC{reg_sign}, pronounced 'cars') focuses on performing fundamental and applied scientific and engineering research emphasizing the environmentally safe, economical use of coal combustion by-products (CCBs). CARRC member organizations, which include utilities and marketers, are key to developing industry-driven research in the area of CCB utilization and ensuring its successful application. The U.S. Department of Energy is a partner in CARRC through the EERC Jointly Sponsored Research Program (JSRP), which provides matching funds for industrial member contributions and facilitates an increased level of effort in CARRC. CARRC tasks were designed to provide information on CCB performance, including environmental performance, engineering performance, favorable economics, and improved life cycle of products and projects. CARRC technical research tasks are developed based on member input and prioritization. CARRC special projects are developed with members and nonmembers to provide similar information and to support activities, including the assembly and interpretation of data, support for standards development and technology transfer, and facilitating product development and testing. CARRC activities from 1998 to 2007 included a range of research tasks, with primary work performed in laboratory tasks developed to answer specific questions or evaluate important fundamental properties of CCBs. CARRC topical reports were prepared on several completed tasks. Specific CARRC 1998B2007 accomplishments included: (1) Development of several ASTM International Standard Guides for CCB utilization applications. (2) Organization and presentation of training courses for CCB professionals and teachers. (3) Development of online resources including the Coal Ash Resource Center, Ash from Biomass in Coal (ABC) of cocombustion ash characteristics, and the Buyer's Guide to Coal-Ash Containing Products. In addition

  14. Decolorization of azo dyes (Direct Blue 151 and Direct Red 31) by moderately alkaliphilic bacterial consortium.

    Science.gov (United States)

    Lalnunhlimi, Sylvine; Krishnaswamy, Veenagayathri

    2016-01-01

    Removal of synthetic dyes is one of the main challenges before releasing the wastes discharged by textile industries. Biodegradation of azo dyes by alkaliphilic bacterial consortium is one of the environmental-friendly methods used for the removal of dyes from textile effluents. Hence, this study presents isolation of a bacterial consortium from soil samples of saline environment and its use for the decolorization of azo dyes, Direct Blue 151 (DB 151) and Direct Red 31 (DR 31). The decolorization of azo dyes was studied at various concentrations (100-300mg/L). The bacterial consortium, when subjected to an application of 200mg/L of the dyes, decolorized DB 151 and DR 31 by 97.57% and 95.25% respectively, within 5 days. The growth of the bacterial consortium was optimized with pH, temperature, and carbon and nitrogen sources; and decolorization of azo dyes was analyzed. In this study, the decolorization efficiency of mixed dyes was improved with yeast extract and sucrose, which were used as nitrogen and carbon sources, respectively. Such an alkaliphilic bacterial consortium can be used in the removal of azo dyes from contaminated saline environment.

  15. Decolorization of azo dyes (Direct Blue 151 and Direct Red 31 by moderately alkaliphilic bacterial consortium

    Directory of Open Access Journals (Sweden)

    Sylvine Lalnunhlimi

    2016-03-01

    Full Text Available Abstract Removal of synthetic dyes is one of the main challenges before releasing the wastes discharged by textile industries. Biodegradation of azo dyes by alkaliphilic bacterial consortium is one of the environmental-friendly methods used for the removal of dyes from textile effluents. Hence, this study presents isolation of a bacterial consortium from soil samples of saline environment and its use for the decolorization of azo dyes, Direct Blue 151 (DB 151 and Direct Red 31 (DR 31. The decolorization of azo dyes was studied at various concentrations (100–300 mg/L. The bacterial consortium, when subjected to an application of 200 mg/L of the dyes, decolorized DB 151 and DR 31 by 97.57% and 95.25% respectively, within 5 days. The growth of the bacterial consortium was optimized with pH, temperature, and carbon and nitrogen sources; and decolorization of azo dyes was analyzed. In this study, the decolorization efficiency of mixed dyes was improved with yeast extract and sucrose, which were used as nitrogen and carbon sources, respectively. Such an alkaliphilic bacterial consortium can be used in the removal of azo dyes from contaminated saline environment.

  16. Development of a consortium for water security and safety: Planning for an early warning system

    Science.gov (United States)

    Clark, R.M.; Adam, N.R.; Atluri, V.; Halem, M.; Vowinkel, E.F.

    2004-01-01

    The events of September 11, 2001 have raised concerns over the safety and security of the Nation's critical infrastructure including water and waste water systems. In June 2002, the U.S. EPA's Region II Office (New York City), in response to concerns over water security, in collaboration with Rutgers University agreed to establish a Regional Drinking Water Security and Safety Consortium (RDWSSC). Members of the consortium include: Rutgers University's Center for Information Management, Integration and Connectivity (CIMIC), American Water (AW), the Passaic Valley Water Commission (PVWC), the North Jersey District Water Supply Commission (NJDWSC), the N.J. Department of Environmental Protection, the U.S. Geological Survey (USGS), and the U.S. Environmental Protection Agencies, Region II Office. In December of 2002 the consortium members signed a memorandum of understanding (MOU) to pursue activities to enhance regional water security. Development of an early warning system for source and distributed water was identified as being of primary importance by the consortium. In this context, an early warning system (EWS) is an integrated system of monitoring stations located at strategic points in a water utilities source waters or in its distribution system, designed to warn against contaminants that might threaten the health and welfare of drinking water consumers. This paper will discuss the consortium's progress in achieving these important objectives.

  17. [Intensification capability of dominant consortium on landscaping water remediation by compound ecological filter].

    Science.gov (United States)

    Liu, Shu-Yu; Fang, Ma; Jiang, Qin-Peng

    2007-06-01

    Zeolite and coal cinder were took as main substrates to construct micro-ecological filter to remedy landscaping water. Screening and domesticating dominant consortium to intensify remedying process, aboriginal colony and naked substrate was contrast. It was showed that, removal efficiency of NH4(+) -N, TN, and TP by and dominant colony increased with rest time. Removal efficiency of NH4(+) -N by naked system was the highest, then dominant consortium system. Removal efficiency of TN by dominant consortium system was the highest and increased evidently with rest time. TP removal by aboriginal colony system was the best. NO2(-) -N in naked system was the lowest, which in dominant consortium system was lower than aboriginal system. TN concentration along hydraulic distance kept falling in dominant colony system; TP concentration along hydraulic distance in aboriginal system kept the lowest. Abundant nitrous and nitride bacterium in dominant colony made nitrification swift and thoroughly, cut accumulation of middle production and hasten nitrogen removal. Dominant consortium kept high activity in long time, which intensified removal of nitrogenous contamination. Cooperation of multi-colony enhanced P removal capacity of system.

  18. Screening of a microbial consortium for highly simultaneous degradation of lignocellulose and chlorophenols.

    Science.gov (United States)

    Liang, Jiajin; Peng, Xiang; Yin, Dexing; Li, Beiyin; Wang, Dehan; Lin, Yunqin

    2015-08-01

    In this work, spent mushroom substrates were utilized for screening a microbial consortium with highly simultaneous degradation of lignocellulose and chlorophenols. The desired microbial consortium OEM1 was gained through successive cultivation for about 50 generations and its stability of composition was verified by denaturing gradient gel electrophoresis (DGGE) during screening process. It could degrade lignocellulose and chlorophenols at around 50% and 100%, respectively, within 7days. The diversity analysis and the growth characteristics of OEM1 during degradation process were investigated by PCR-DGGE combined with clone and sequence. The results indicated that OEM1 consisted of 31 strains. Proteobacteria and Bacteroidetes were the predominant bacterial groups. The dynamic change of OEM1 illustrated that consortium community structure was effected by pH and substrate alteration and tended to be stable after 6days' cultivation. Furthermore, bacteria (11 strains) and actinomycetes (2 strains) were obtained based on plate isolation and identified via 16S rDNA sequence. PMID:25974352

  19. Ecofriendly degradation, decolorization and detoxification of textile effluent by a developed bacterial consortium.

    Science.gov (United States)

    Phugare, Swapnil S; Kalyani, Dayanand C; Surwase, Shripad N; Jadhav, Jyoti P

    2011-07-01

    Present study illustrates the effectual decolorization and degradation of the textile effluent using a developed bacterial consortium SDS, consisted of bacterial species Providencia sp. SDS and Pseudomonas aeuroginosa strain BCH, originally isolated from dye contaminated soil. The intensive metabolic activity of the consortium SDS led to complete decolorization of textile effluent within 20 h at pH 7 and temperature 30°C. Significant induction in the activities of veratryl alcohol oxidase, laccase, azoreductase and DCIP reductase were observed during decolorization, which indicates their involvement in decolorization and degradation process. The decolorization and biodegradation was monitored using UV-vis spectroscopy, IR spectroscopy, HPLC and HPTLC analysis. Toxicological analysis of effluent before and after treatment was performed using classical Allium cepa test. Investigations of various toxicological parameters viz, oxidative stress response, cytotoxicity, genotoxicity and phytotoxicity, collectively concludes that, the toxicity of effluent reduces significantly after treatment with consortium SDS.

  20. Institutional support for the Utah Consortium for Energy Research and Education. Annual report

    Energy Technology Data Exchange (ETDEWEB)

    1979-06-01

    The Utah Consortium for Energy Research and Education is made up of three colleges and universities in Utah. The scope of the Consortium plan is the marshalling of the academic research resources, as well as the appropriate non-academic resources within Utah to pursue, as appropriate, energy-related research activities. The heart of this effort has been the institutional contract between DOE and the University of Utah, acting as fiscal agent for the Consortium. Sixteen programs are currently being funded, but only ten of the projects are described in this report. Three projects are on fission/fusion; three on environment and safety; four on fossil energy; three on basic energy sciences; one each on conservation, geothermal, and solar.

  1. Performance assessment of a submerged membrane bioreactor using a novel microbial consortium.

    Science.gov (United States)

    Chon, Kangmin; Lee, Kyungpyo; Kim, In-Soo; Jang, Am

    2016-06-01

    The performance of a submerged membrane bioreactor (MBR) with and without a novel microbial consortium (NMBR vs. CMBR) was compared to provide deeper insights into the effects of changes in water quality and dissolved organic matter (DOM) characteristics by a novel microbial consortium on the fouling characteristics of MBR processes. Despite similar operating conditions and identical DOM properties in the feed waters, NMBR exhibited a lower propensity to release polysaccharide-like compounds with low molecular weight by bacterial activities compared to CMBR. These compounds have a great fouling potential for MBR processes. Therefore, an increase in the transmembrane pressure (TMP) of NMBR (normalized TMP (TMP/TMP0): 1.14) was much slower and less significant than that observed in CMBR (TMP/TMP0: 2.61). These observations imply that the novel microbial consortium can efficiently mitigate membrane fouling by hydrophilic DOM in MBR processes.

  2. Ecofriendly degradation, decolorization and detoxification of textile effluent by a developed bacterial consortium.

    Science.gov (United States)

    Phugare, Swapnil S; Kalyani, Dayanand C; Surwase, Shripad N; Jadhav, Jyoti P

    2011-07-01

    Present study illustrates the effectual decolorization and degradation of the textile effluent using a developed bacterial consortium SDS, consisted of bacterial species Providencia sp. SDS and Pseudomonas aeuroginosa strain BCH, originally isolated from dye contaminated soil. The intensive metabolic activity of the consortium SDS led to complete decolorization of textile effluent within 20 h at pH 7 and temperature 30°C. Significant induction in the activities of veratryl alcohol oxidase, laccase, azoreductase and DCIP reductase were observed during decolorization, which indicates their involvement in decolorization and degradation process. The decolorization and biodegradation was monitored using UV-vis spectroscopy, IR spectroscopy, HPLC and HPTLC analysis. Toxicological analysis of effluent before and after treatment was performed using classical Allium cepa test. Investigations of various toxicological parameters viz, oxidative stress response, cytotoxicity, genotoxicity and phytotoxicity, collectively concludes that, the toxicity of effluent reduces significantly after treatment with consortium SDS. PMID:21524793

  3. Bacterial consortium for copper extraction from sulphide ore consisting mainly of chalcopyrite

    Science.gov (United States)

    Romo, E.; Weinacker, D.F.; Zepeda, A.B.; Figueroa, C.A.; Chavez-Crooker, P.; Farias, J.G.

    2013-01-01

    The mining industry is looking forward for bacterial consortia for economic extraction of copper from low-grade ores. The main objective was to determine an optimal bacterial consortium from several bacterial strains to obtain copper from the leach of chalcopyrite. The major native bacterial species involved in the bioleaching of sulphide ore (Acidithiobacillus ferrooxidans, Acidithiobacillus thiooxidans, Leptospirillum ferrooxidans and Leptospirillum ferriphilum) were isolated and the assays were performed with individual bacteria and in combination with At. thiooxidans. In conclusion, it was found that the consortium integrated by At. ferrooxidans and At. thiooxidans removed 70% of copper in 35 days from the selected ore, showing significant differences with the other consortia, which removed only 35% of copper in 35 days. To validate the assays was done an escalation in columns, where the bacterial consortium achieved a higher percentage of copper extraction regarding to control. PMID:24294251

  4. Bacterial consortium for copper extraction from sulphide ore consisting mainly of chalcopyrite

    Directory of Open Access Journals (Sweden)

    E. Romo

    2013-01-01

    Full Text Available The mining industry is looking forward for bacterial consortia for economic extraction of copper from low-grade ores. The main objective was to determine an optimal bacterial consortium from several bacterial strains to obtain copper from the leach of chalcopyrite. The major native bacterial species involved in the bioleaching of sulphide ore (Acidithiobacillus ferrooxidans, Acidithiobacillus thiooxidans, Leptospirillum ferrooxidans and Leptospirillum ferriphilum were isolated and the assays were performed with individual bacteria and in combination with At. thiooxidans. In conclusion, it was found that the consortium integrated by At. ferrooxidans and At. thiooxidans removed 70% of copper in 35 days from the selected ore, showing significant differences with the other consortia, which removed only 35% of copper in 35 days. To validate the assays was done an escalation in columns, where the bacterial consortium achieved a higher percentage of copper extraction regarding to control.

  5. Phylogenetic characterization of a corrosive consortium isolated from a sour gas pipeline.

    Science.gov (United States)

    Jan-Roblero, J; Romero, J M; Amaya, M; Le Borgne, S

    2004-06-01

    Biocorrosion is a common problem in oil and gas industry facilities. Characterization of the microbial populations responsible for biocorrosion and the interactions between different microorganisms with metallic surfaces is required in order to implement efficient monitoring and control strategies. Denaturing gradient gel electrophoresis (DGGE) analysis was used to separate PCR products and sequence analysis revealed the bacterial composition of a consortium obtained from a sour gas pipeline in the Gulf of Mexico. Only one species of sulfate-reducing bacteria (SRB) was detected in this consortium. The rest of the population consisted of enteric bacteria with different characteristics and metabolic capabilities potentially related to biocorrosion. Therefore, several types of bacteria may be involved in biocorrosion arising from natural biofilms that develop in industrial facilities. The low abundance of the detected SRB was evidenced by environmental scanning electron microscopy (ESEM). In addition, the localized corrosion of pipeline steel in the presence of the consortium was clearly observed by ESEM after removing the adhered bacteria.

  6. The Toxicology Investigators Consortium Case Registry--the 2012 experience.

    Science.gov (United States)

    Wiegand, Timothy; Wax, Paul; Smith, Eric; Hart, Katherine; Brent, Jeffrey

    2013-12-01

    In 2010, the American College of Medical Toxicology (ACMT) established its Case Registry, the Toxicology Investigators Consortium (ToxIC). All cases are entered prospectively and include only suspected and confirmed toxic exposures cared for at the bedside by board-certified or board-eligible medical toxicologists at its participating sites. The primary aims of establishing this Registry include the development of a realtime toxico-surveillance system in order to identify and describe current or evolving trends in poisoning and to develop a research tool in toxicology. ToxIC allows for extraction of data from medical records from multiple sites across a national and international network. All cases seen by medical toxicologists at participating institutions were entered into the database. Information characterizing patients entered in 2012 was tabulated and data from the previous years including 2010 and 2011 were included so that cumulative numbers and trends could be described as well. The current report includes data through December 31st, 2012. During 2012, 38 sites with 68 specific institutions contributed a total of 7,269 cases to the Registry. The total number of cases entered into the Registry at the end of 2012 was 17,681. Emergency departments remained the most common source of consultation in 2012, accounting for 61 % of cases. The most common reason for consultation was for pharmaceutical overdose, which occurred in 52 % of patients including intentional (41 %) and unintentional (11 %) exposures. The most common classes of agents were sedative-hypnotics (1,422 entries in 13 % of cases) non-opioid analgesics (1,295 entries in 12 % of cases), opioids (1,086 entries in 10 % of cases) and antidepressants (1,039 entries in 10 % of cases). N-acetylcysteine (NAC) was the most common antidote administered in 2012, as it was in previous years, followed by the opioid antagonist naloxone, sodium bicarbonate, physostigmine and flumazenil. Anti-crotalid Fab

  7. The Toxicology Investigators Consortium Case Registry--the 2012 experience.

    Science.gov (United States)

    Wiegand, Timothy; Wax, Paul; Smith, Eric; Hart, Katherine; Brent, Jeffrey

    2013-12-01

    In 2010, the American College of Medical Toxicology (ACMT) established its Case Registry, the Toxicology Investigators Consortium (ToxIC). All cases are entered prospectively and include only suspected and confirmed toxic exposures cared for at the bedside by board-certified or board-eligible medical toxicologists at its participating sites. The primary aims of establishing this Registry include the development of a realtime toxico-surveillance system in order to identify and describe current or evolving trends in poisoning and to develop a research tool in toxicology. ToxIC allows for extraction of data from medical records from multiple sites across a national and international network. All cases seen by medical toxicologists at participating institutions were entered into the database. Information characterizing patients entered in 2012 was tabulated and data from the previous years including 2010 and 2011 were included so that cumulative numbers and trends could be described as well. The current report includes data through December 31st, 2012. During 2012, 38 sites with 68 specific institutions contributed a total of 7,269 cases to the Registry. The total number of cases entered into the Registry at the end of 2012 was 17,681. Emergency departments remained the most common source of consultation in 2012, accounting for 61 % of cases. The most common reason for consultation was for pharmaceutical overdose, which occurred in 52 % of patients including intentional (41 %) and unintentional (11 %) exposures. The most common classes of agents were sedative-hypnotics (1,422 entries in 13 % of cases) non-opioid analgesics (1,295 entries in 12 % of cases), opioids (1,086 entries in 10 % of cases) and antidepressants (1,039 entries in 10 % of cases). N-acetylcysteine (NAC) was the most common antidote administered in 2012, as it was in previous years, followed by the opioid antagonist naloxone, sodium bicarbonate, physostigmine and flumazenil. Anti-crotalid Fab

  8. Extremely-halotolerant bacterial consortium for the biodegradation of crude oil in saline environments

    Directory of Open Access Journals (Sweden)

    María Piedad Díaz

    2011-12-01

    Full Text Available Results of the application of a novel bacterial consortium extremely-halotolerant for the biodegradation of crude oil using free and immobilized cell systems, in media with salinities ranged from zero to 220 g/L, are described. Its effectiveness increased when the cells were immobilized on polyurethane foam, polypropylene fibers, scourers and Celatom and the salinity of the culture medium surpassed 20 g/L. Four of the microorganisms belonging to the consortium grew in media with salinities varying from zero to 320 g/L and are amongst the most halotolerant microorganisms described up to now. 

  9. Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium

    DEFF Research Database (Denmark)

    Pearce, C L; Near, A M; Van Den Berg, D J;

    2009-01-01

    The search for genetic variants associated with ovarian cancer risk has focused on pathways including sex steroid hormones, DNA repair, and cell cycle control. The Ovarian Cancer Association Consortium (OCAC) identified 10 single-nucleotide polymorphisms (SNPs) in genes in these pathways, which had...... been genotyped by Consortium members and a pooled analysis of these data was conducted. Three of the 10 SNPs showed evidence of an association with ovarian cancer at P... and risk of ovarian cancer suggests that this pathway may be involved in ovarian carcinogenesis. Additional follow-up is warranted....

  10. A consortium approach for disaster relief and technology research and development: Fire station earth

    Science.gov (United States)

    Ling, Douglas C.

    1992-06-01

    A new paradigm is proposed for alleviating the chronic problem of inadequate response to natural and man-made disasters. Fundamental flaws and weaknesses in the current disaster mitigation system point to the need for an international consortium involving governments, academia, industry, and businesses. Recent changes in social and political framework offer a unique opportunity of rethink and reform the existing disaster response mechanism. Benefits of a collaborative consortium approach may include commercial incentives, improved cost effectiveness, coherence in research and development efforts, conduciveness for long-term planning, and improved deployment of technology for disaster mitigation.

  11. Evaluating robustness of a diesel-degrading bacterial consortium isolated from contaminated soil

    DEFF Research Database (Denmark)

    Sydow, Mateusz; Owsianiak, Mikolaj; Szczepaniak, Zuzanna;

    2016-01-01

    kinetics on individual hydrocarbons. However, despite this low resistance, structural and functional resilience were high, as verified by re-exposing the hydrocarbon-perturbed consortium to diesel fuel. The high resilience is either due to the short exposure time, insufficient for permanent changes...... structural resistance. The structural resistance was low, with changes in relative abundances of up to four orders of magnitude, depending on hydrocarbon type and bacterial taxon. This low resistance is explained by the presence of hydrocarbon-degrading specialists in the consortium and differences in growth...

  12. Burden of cancer in a large consortium of prospective cohorts in Europe

    OpenAIRE

    Tsilidis, KK; Papadimitriou, N; Capothanassi, D; Bamia, C.; Benetou, V; Jenab, M; Freisling, H; Kee, F.; Nelen, A; O'Doherty, MG; Scott, A.; Soerjomataram, I; Tjønneland, A; May, AM; Ramón Quirós, J

    2016-01-01

    Disability-adjusted life-years (DALYs) are an indicator of mortality, morbidity, and disability. We calculated DALYs for cancer in middle-aged and older adults participating in the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) consortium.A total of 90 199 participants from five European cohorts with 10 455 incident cancers and 4399 deaths were included in this study. DALYs were calculated as the sum of the years of life lost because of premature ...

  13. Oak woodlands and forests fire consortium: A regional view of fire science sharing

    Science.gov (United States)

    Grabner, Keith W.; Stambaugh, Michael C.; Marschall, Joseph M.; Abadir, Erin R.

    2013-01-01

    The Joint Fire Science Program established 14 regional fire science knowledge exchange consortia to improve the delivery of fire science information and communication among fire managers and researchers. Consortia were developed regionally to ensure that fire science information is tailored to meet regional needs. In this paper, emphasis was placed on the Oak Woodlands and Forests Fire Consortium to provide an inside view of how one regional consortium is organized and its experiences in sharing fire science through various social media, conference, and workshop-based fire science events.

  14. The Consortium and the Commissioner: A Grass Roots Tale of Fighting High Stakes Graduation Testing in New York

    Science.gov (United States)

    Knecht, Doug

    2007-01-01

    The following paper provides a case study of the resistance of the New York Performance Standards Consortium to the state's unitary high stakes testing policy from 1998 to 2006. After detailing the history of the grass roots actions undertaken by the group of alternative high schools called "The Consortium," the analysis seeks to apply…

  15. 77 FR 25406 - Consortium on “Concrete Rheology: Enabling Metrology (CREME)”: Membership Fee Update

    Science.gov (United States)

    2012-04-30

    ... in participating in the CREME Consortium discussed membership fees and agreed to the following revisions to the membership fee structure. Initial membership fees will be Twenty Five Thousand Dollars ($25... membership fees for participation in the CREME consortium would be Twenty-five Thousand ($25,000) per...

  16. The Historically Black Colleges and Universities/Minority Institutions Environmental Technology Consortium annual report draft, 1995--1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The HBCU/MI ET Consortium was established in January 1990, through a memorandum of Understanding (MOU) among its member institutions. This group of research-oriented Historically Black Colleges and Universities and Minority Institutions (HBCUs/MIs) agreed to work together to initiate or revise educational programs, develop research partnerships with public and private sector organizations, and promote technology development and transfer to address the nation`s critical environmental problems. While the Consortium`s Research, Education and Technology Transfer (RETT) Plan is the cornerstone of its overall program efforts, the initial programmatic activities of the Consortium focused on environmental education at all levels with the objective of addressing the underrepresentation of minorities in the environmental professions. This 1996 Annual Report provides an update on the activities of the Consortium with a focus on environmental curriculum development for the Technical Qualifications Program (TQP) and Education for Sustainability.

  17. Consortia for Engineering, Science and Technology Libraries in India: A Case Study of INDEST Consortium

    Science.gov (United States)

    Pathak, S. K.; Deshpande, N. J.

    2007-10-01

    The present scenario of the INDEST Consortium among engineering, science and technology (including astronomy and astrophysics) libraries in India is discussed. The Indian National Digital Library in Engineering Sciences & Technology (INDEST) Consortium is a major initiative of the Ministry of Human Resource Development, Government of India. The INDEST Consortium provides access to 16 full text e-resources and 7 bibliographic databases for 166 institutions as members who are taking advantage of cost effective access to premier resources in engineering, science and technology, including astronomy and astrophysics. Member institutions can access over 6500 e-journals from 1092 publishers. Out of these, over 150 e-journals are exclusively for the astronomy and physics community. The current study also presents a comparative analysis of the key features of nine major services, viz. ACM Digital Library, ASCE Journals, ASME Journals, EBSCO Databases (Business Source Premier), Elsevier's Science Direct, Emerald Full Text, IEEE/IEE Electronic Library Online (IEL), ProQuest ABI/INFORM and Springer Verlag's Link. In this paper, the limitations of this consortium are also discussed.

  18. Biological treatment of textile dyes by agar-agar immobilized consortium in a packed bed reactor.

    Science.gov (United States)

    Patel, Yogesh; Gupte, Akshaya

    2015-03-01

    The decolorization of Acid Maroon V was investigated using bacterial consortium EDPA containing Enterobacter dissolvens AGYP1 and Pseudomonas aeruginosa AGYP2 immobilized in different entrapment matrices. The consortium displayed 96% removal of dye (100 mg/l) within 6 h when immobilized in agar-agar. Under optimum concentrations of agar-agar (3.0% w/v) and cell biomass (0.9 g% w/v), the consortium displayed decolorization for 18 successive batches of Acid Maroon V and also decolorized 14 other different textile dyes. A packed bed reactor under batch mode showed 89% decolorization of dye after 56 repetitive cycles. Under continuous flow mode, maximum color removal was achieved with bed length of 36 cm, hydraulic retention time of 2.66 h, and dye concentration of 100 mg/l. Additionally, the reactor decolorized relatively higher concentrations (100-2000 mg/l) of dye. The synthetic dye wastewater containing five textile dyes was decolorized 92% with 62% COD reduction using an immobilized consortium.

  19. A History of the Liberal Arts Computer Science Consortium and Its Model Curricula

    Science.gov (United States)

    Bruce, Kim B.; Cupper, Robert D.; Scot Drysdale, Robert L.

    2010-01-01

    With the support of a grant from the Sloan Foundation, nine computer scientists from liberal arts colleges came together in October, 1984 to form the Liberal Arts Computer Science Consortium (LACS) and to create a model curriculum appropriate for liberal arts colleges. Over the years the membership has grown and changed, but the focus has remained…

  20. Massachusetts Workplace Literacy Consortium. NWLP Wave 6. Annual Performance Report, June 12, 1996-June 12, 1997.

    Science.gov (United States)

    Massachusetts Workplace Literacy Consortium, Boston.

    This performance report, presented in chart form, outlines progress on five goals of the Massachusetts Workplace Literacy Consortium. Under each goal are a number of objectives, and for each objective the chart describes activities, accomplishments, responsible party, and time frame. Goals are as follows: (1) "Enhance the Productivity and Quality…

  1. The ENIGMA Consortium : large-scale collaborative analyses of neuroimaging and genetic data

    NARCIS (Netherlands)

    Thompson, Paul M.; Stein, Jason L.; Medland, Sarah E.; Hibar, Derrek P.; Vasquez, Alejandro Arias; Renteria, Miguel E.; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J.; Martin, Nicholas G.; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C.; Andreassen, Ole A.; Apostolova, Liana G.; Appel, Katja; Armstrong, Nicola J.; Aribisala, Benjamin; Bastin, Mark E.; Bauer, Michael; Bearden, Carrie E.; Bergmann, Orjan; Binder, Elisabeth B.; Blangero, John; Bockholt, Henry J.; Boen, Erlend; Bois, Catherine; Boomsma, Dorret I.; Booth, Tom; Bowman, Ian J.; Bralten, Janita; Brouwer, Rachel M.; Brunner, Han G.; Brohawn, David G.; Buckner, Randy L.; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R.; Calhoun, Vince D.; Cannon, Dara M.; Cantor, Rita M.; Carless, Melanie A.; Caseras, Xavier; Cavalleri, Gianpiero L.; Chakravarty, M. Mallar; Chang, Kiki D.; Ching, Christopher R. K.; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P.; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E.; Czisch, Michael; Deary, Ian J.; de Geus, Eco J. C.; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I.; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D.; Ehrlich, Stefan; Ekman, Carl Johan; Elvsashagen, Torbjorn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernandez, Guillen; Fisher, Simon E.; Foroud, Tatiana; Fox, Peter T.; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C.; Godlewska, Beata; Goldstein, Rita Z.; Gollub, Randy L.; Grabe, Hans J.; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel E.; Gur, Ruben C.; Goering, Harald H. H.; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey B.; Hall, Jeremy; Hardy, John; Hartman, Catharina A.; Hass, Johanna; Hatton, Sean N.; Haukvik, Unn K.; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian B.; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter J.; Hollinshead, Marisa; Holmes, Avram J.; Homuth, Georg; Hoogman, Martine; Hong, L. Elliot; Hosten, Norbert; Hottenga, Jouke-Jan; Pol, Hilleke E. Hulshoff; Hwang, Kristy S.; Jack, Clifford R.; Jenkinson, Mark; Johnston, Caroline; Joensson, Erik G.; Kahn, Rene S.; Kasperaviciute, Dalia; Kelly, Sinead; Kim, Sungeun; Kochunov, Peter; Koenders, Laura; Kraemer, Bernd; Kwok, John B. J.; Lagopoulos, Jim; Laje, Gonzalo; Landen, Mikael; Landman, Bennett A.; Lauriello, John; Lawrie, Stephen M.; Lee, Phil H.; Le Hellard, Stephanie; Lemaitre, Herve; Leonardo, Cassandra D.; Li, Chiang-shan; Liberg, Benny; Liewald, David C.; Liu, Xinmin; Lopez, Lorna M.; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise W. J.; MacQueen, Glenda M.; Malt, Ulrik F.; Mandl, Rene; Manoach, Dara S.; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen A.; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; McIntosh, Andrew M.; McMahon, Francis J.; McMahon, Katie L.; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant W.; Morris, Derek W.; Moses, Eric K.; Mueller, Bryon A.; Munoz Maniega, Susana; Muehleisen, Thomas W.; Mueller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas E.; Nilsson, Lars-Goeran; Nugent, Allison C.; Nyberg, Lars; Olvera, Rene L.; Oosterlaan, Jaap; Ophoff, Roel A.; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey D.; Penninx, Brenda W.; Peterson, Charles P.; Pfennig, Andrea; Phillips, Mary; Pike, G. Bruce; Poline, Jean-Baptiste; Potkin, Steven G.; Puetz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon L.; Roffman, Joshua L.; Roiz-Santianez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma J.; Royle, Natalie A.; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder S.; Salami, Alireza; Satterthwaite, Theodore D.; Savitz, Jonathan; Saykin, Andrew J.; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo G.; Schork, Andrew J.; Schulz, S. Charles; Schuer, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody M.; Simmons, Andrew; Sisodiya, Sanjay M.; Smith, Colin; Smoller, Jordan W.; Soares, Jair C.; Sponheim, Scott R.; Sprooten, Emma; Starr, John M.; Steen, Vidar M.; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Saemann, Philipp G.; Teumer, Alexander; Toga, Arthur W.; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van den Heuvel, Martijn; van der Wee, Nic J.; van Eijk, Kristel; van Erp, Theo G. M.; van Haren, Neeltje E. M.; van 't Ent, Dennis; van Tol, Marie-Jose; Hernandez, Maria C. Valdes; Veltman, Dick J.; Versace, Amelia; Voelzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna M.; Weale, Michael E.; Weiner, Michael W.; Wen, Wei; Westlye, Lars T.; Whalley, Heather C.; Whelan, Christopher D.; White, Tonya; Winkler, Anderson M.; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel P.; Thalamuthu, Anbupalam; Schofield, Peter R.; Freimer, Nelson B.; Lawrence, Natalia S.; Drevets, Wayne

    2014-01-01

    The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics

  2. The ENIGMA Consortium: Large-scale collaborative analyses of neuroimaging and genetic data

    NARCIS (Netherlands)

    P.M. Thompson (Paul); J.L. Stein; S.E. Medland (Sarah Elizabeth); D.P. Hibar (Derrek); A.A. Vásquez (Arias); M.E. Rentería (Miguel); R. Toro (Roberto); N. Jahanshad (Neda); G. Schumann (Gunter); B. Franke (Barbara); M.J. Wright (Margaret); N.G. Martin (Nicholas); I. Agartz (Ingrid); M. Alda (Martin); S. Alhusaini (Saud); L. Almasy (Laura); J. Almeida (Julia); K. Alpert (Kathryn); N.C. Andreasen; O.A. Andreassen (Ole); L.G. Apostolova (Liana); K. Appel (Katja); N.J. Armstrong (Nicola); B. Aribisala (Benjamin); M.E. Bastin (Mark); M. Bauer (Michael); C.E. Bearden (Carrie); Ø. Bergmann (Ørjan); E.B. Binder (Elisabeth); J. Blangero (John); H.J. Bockholt; E. Bøen (Erlend); M. Bois (Monique); D.I. Boomsma (Dorret); T. Booth (Tom); I.J. Bowman (Ian); L.B.C. Bralten (Linda); R.M. Brouwer (Rachel); H.G. Brunner; D.G. Brohawn (David); M. Buckner; J.K. Buitelaar (Jan); K. Bulayeva (Kazima); J. Bustillo; V.D. Calhoun (Vince); D.M. Cannon (Dara); R.M. Cantor; M.A. Carless (Melanie); X. Caseras (Xavier); G. Cavalleri (Gianpiero); M.M. Chakravarty (M. Mallar); K.D. Chang (Kiki); C.R.K. Ching (Christopher); A. Christoforou (Andrea); S. Cichon (Sven); V.P. Clark; P. Conrod (Patricia); D. Coppola (Domenico); B. Crespo-Facorro (Benedicto); J.E. Curran (Joanne); M. Czisch (Michael); I.J. Deary (Ian); E.J.C. de Geus (Eco); A. den Braber (Anouk); G. Delvecchio (Giuseppe); C. Depondt (Chantal); L. de Haan (Lieuwe); G.I. de Zubicaray (Greig); D. Dima (Danai); R. Dimitrova (Rali); S. Djurovic (Srdjan); H. Dong (Hongwei); D.J. Donohoe (Dennis); A. Duggirala (Aparna); M.D. Dyer (Matthew); S.M. Ehrlich (Stefan); C.J. Ekman (Carl Johan); T. Elvsåshagen (Torbjørn); L. Emsell (Louise); S. Erk; T. Espeseth (Thomas); J. Fagerness (Jesen); S. Fears (Scott); I. Fedko (Iryna); G. Fernandez (Guillén); S.E. Fisher (Simon); T. Foroud (Tatiana); P.T. Fox (Peter); C. Francks (Clyde); S. Frangou (Sophia); E.M. Frey (Eva Maria); T. Frodl (Thomas); V. Frouin (Vincent); H. Garavan (Hugh); S. Giddaluru (Sudheer); D.C. Glahn (David); B. Godlewska (Beata); R.Z. Goldstein (Rita); R.L. Gollub (Randy); H.J. Grabe (Hans Jörgen); O. Grimm (Oliver); O. Gruber (Oliver); T. Guadalupe (Tulio); R.E. Gur (Raquel); R.C. Gur (Ruben); H.H.H. Göring (Harald); S. Hagenaars (Saskia); T. Hajek (Tomas); G.B. Hall (Garry); J. Hall (Jeremy); J. Hardy (John); C.A. Hartman (Catharina); J. Hass (Johanna); W. Hatton; U.K. Haukvik (Unn); K. Hegenscheid (Katrin); J. Heinz (Judith); I.B. Hickie (Ian); B.C. Ho (Beng ); D. Hoehn (David); P.J. Hoekstra (Pieter); M. Hollinshead (Marisa); A.J. Holmes (Avram); G. Homuth (Georg); M. Hoogman (Martine); L.E. Hong (L.Elliot); N. Hosten (Norbert); J.J. Hottenga (Jouke Jan); H.E. Hulshoff Pol (Hilleke); K.S. Hwang (Kristy); C.R. Jack Jr. (Clifford); S. Jenkinson (Sarah); C. Johnston; E.G. Jönsson (Erik); R.S. Kahn (René); D. Kasperaviciute (Dalia); S. Kelly (Steve); S. Kim (Shinseog); P. Kochunov (Peter); L. Koenders (Laura); B. Krämer (Bernd); J.B.J. Kwok (John); J. Lagopoulos (Jim); G. Laje (Gonzalo); M. Landén (Mikael); B.A. Landman (Bennett); J. Lauriello; S. Lawrie (Stephen); P.H. Lee (Phil); S. Le Hellard (Stephanie); H. Lemaître (Herve); C.D. Leonardo (Cassandra); C.-S. Li (Chiang-shan); B. Liberg (Benny); D.C. Liewald (David C.); X. Liu (Xinmin); L.M. Lopez (Lorna); E. Loth (Eva); A. Lourdusamy (Anbarasu); M. Luciano (Michelle); F. MacCiardi (Fabio); M.W.J. Machielsen (Marise); G.M. MacQueen (Glenda); U.F. Malt (Ulrik); R. Mandl (René); D.S. Manoach (Dara); J.-L. Martinot (Jean-Luc); M. Matarin (Mar); R. Mather; M. Mattheisen (Manuel); M. Mattingsdal (Morten); A. Meyer-Lindenberg; C. McDonald (Colm); A.M. McIntosh (Andrew); F.J. Mcmahon (Francis J); K.L. Mcmahon (Katie); E. Meisenzahl (Eva); I. Melle (Ingrid); Y. Milaneschi (Yuri); S. Mohnke (Sebastian); G.W. Montgomery (Grant); D.W. Morris (Derek W); E.K. Moses (Eric); B.A. Mueller (Bryon ); S. Muñoz Maniega (Susana); T.W. Mühleisen (Thomas); B. Müller-Myhsok (Bertram); B. Mwangi (Benson); M. Nauck (Matthias); K. Nho (Kwangsik); T.E. Nichols (Thomas); L.G. Nilsson; A.C. Nugent (Allison); L. Nyberg (Lisa); R.L. Olvera (Rene); J. Oosterlaan (Jaap); R.A. Ophoff (Roel); M. Pandolfo (Massimo); M. Papalampropoulou-Tsiridou (Melina); M. Papmeyer (Martina); T. Paus (Tomas); Z. Pausova (Zdenka); G. Pearlson (Godfrey); B.W.J.H. Penninx (Brenda); C.P. Peterson (Charles); A. Pfennig (Andrea); M. Phillips (Mary); G.B. Pike (G Bruce); J.B. Poline (Jean Baptiste); S.G. Potkin (Steven); B. Pütz (Benno); A. Ramasamy (Adaikalavan); J. Rasmussen (Jerod); M. Rietschel (Marcella); M. Rijpkema (Mark); S.L. Risacher (Shannon); J.L. Roffman (Joshua); R. Roiz-Santiañez (Roberto); N. Romanczuk-Seiferth (Nina); E.J. Rose (Emma); N.A. Royle (Natalie); D. Rujescu (Dan); M. Ryten (Mina); P.S. Sachdev (Perminder); A. Salami (Alireza); T.D. Satterthwaite (Theodore); J. Savitz (Jonathan); A.J. Saykin (Andrew); C. Scanlon (Cathy); L. Schmaal (Lianne); H. Schnack (Hugo); N.J. Schork (Nicholas); S.C. Schulz (S.Charles); R. Schür (Remmelt); L.J. Seidman (Larry); L. Shen (Li); L. Shoemaker (Lawrence); A. Simmons (Andrew); S.M. Sisodiya (Sanjay); C. Smith (Colin); J.W. Smoller; J.C. Soares (Jair); S.R. Sponheim (Scott); R. Sprooten (Roy); J.M. Starr (John); V.M. Steen (Vidar); S. Strakowski (Stephen); V.M. Strike (Vanessa); J. Sussmann (Jessika); P.G. Sämann (Philipp); A. Teumer (Alexander); A.W. Toga (Arthur); D. Tordesillas-Gutierrez (Diana); D. Trabzuni (Danyah); S. Trost (Sarah); J. Turner (Jessica); M. van den Heuvel (Martijn); N.J. van der Wee (Nic); K.R. van Eijk (Kristel); T.G.M. van Erp (Theo G.); N.E.M. van Haren (Neeltje E.); D. van 't Ent (Dennis); M.J.D. van Tol (Marie-José); M.C. Valdés Hernández (Maria); D.J. Veltman (Dick); A. Versace (Amelia); H. Völzke (Henry); R. Walker (Robert); H.J. Walter (Henrik); L. Wang (Lei); J.M. Wardlaw (J.); M.E. Weale (Michael); M.W. Weiner (Michael); W. Wen (Wei); L.T. Westlye (Lars); H.C. Whalley (Heather); C.D. Whelan (Christopher); T.J.H. White (Tonya); A.M. Winkler (Anderson); K. Wittfeld (Katharina); G. Woldehawariat (Girma); A. Björnsson (Asgeir); D. Zilles (David); M.P. Zwiers (Marcel); A. Thalamuthu (Anbupalam); C.J. Schofield (Christopher); N.B. Freimer (Nelson); N.S. Lawrence (Natalia); D.A. Drevets (Douglas)

    2014-01-01

    textabstractThe Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscien

  3. Developing a community-based graduate medical education consortium for residency sponsorship: one community's experience.

    Science.gov (United States)

    Broderick, Peter W; Nocella, Kiki

    2012-08-01

    Faced with a funding crisis that threatened a single-sponsor family medicine residency program critical to a county-wide health system, health care organizations located in the California community described in this article formed a nonprofit, corporate graduate medical education (GME) consortium to sponsor a new residency program. Institutional GME sponsors are typically single hospitals or academic medical centers associated with medical schools. However, as the authors describe, community-based residency sponsorship through a GME consortium can allow multiple stakeholders to assume a model of shared ownership that reflects alignment of pooled community resources with the distributive benefits associated with residencies. Although this community's stakeholders encountered expected governance complexities as they worked to reconcile competing interests, they successfully collaborated to develop the Valley Consortium for Medical Education by addressing a variety of fiscal, workforce benefit, and community coordination challenges. The authors describe the key phases of development and discuss the challenges that must be overcome to establish an institutional sponsor with multiple stakeholders. The financial pressure that traditional institutional sponsors are experiencing with the inexorable decline in GME funding may prompt them to explore partnerships in which they can share expenses for the mutual benefit of physician workforce development. The authors believe that the community-based GME consortium is a viable model to consider. PMID:22722363

  4. IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies

    DEFF Research Database (Denmark)

    Pedersen, Nancy L; Christensen, Kaare; Dahl, Anna K;

    2013-01-01

    The Interplay of Genes and Environment across Multiple Studies (IGEMS) group is a consortium of eight longitudinal twin studies established to explore the nature of social context effects and gene-environment interplay in late-life functioning. The resulting analysis of the combined data from ove...

  5. Effectiveness of Endophytic Bacterial Consortium of Coffee Plant on Mortality of Pratylenchus Coffeae in Vitro

    Directory of Open Access Journals (Sweden)

    dwi halimah

    2015-12-01

    Full Text Available Bacteria live in wild in form of a consortium. Use of microbial consortium tends to give better results than single isolate, because the action of enzyme of each type of microbe can complement each other in order to survive. This study aimed to study the effectiveness of bacterial endophytic consortium from coffee plant on plant growth and mortality of parasitic nematodes in coffee. Isolation of bacteria is conducted  by growing the crushed roots, stems and leaves of coffee on 20% TSA media, then testing their hemolysis and hypersensitivity reaction. Selected isolates were tested on their effect on the growth of seedling and Pratylenchus coffeae mortality, as well as their chitinolytic, proteolytic, lipolytic, HCN production, dissolution of phosphate (P and fixation of nitrogen (N2 abilities. The results showed that from 27 isolates of the consortium, 23 isolates showed negative reaction to hypersensitive test and 9 isolates to hemolysis test. The highest mortality rate was shown by K6 isolate (65.8%. The highest growth was shown by K15 and K 21 isolates while the highest root length by K21 isolate. Further analisys showed that 100% of the isolates could hydrolyze proteases, lipid, and produce HCN, while chitinolytic activity was shown by 78% isolates which could fix N2 and 11% of isolates could dissolve phosphate.

  6. Medical Physics Residency Consortium: collaborative endeavors to meet the ABR 2014 certification requirements.

    Science.gov (United States)

    Parker, Brent C; Duhon, John; Yang, Claus C; Wu, H Terry; Hogstrom, Kenneth R; Gibbons, John P

    2014-03-06

    In 2009, Mary Bird Perkins Cancer Center (MBPCC) established a Radiation Oncology Physics Residency Program to provide opportunities for medical physics residency training to MS and PhD graduates of the CAMPEP-accredited Louisiana State University (LSU)-MBPCC Medical Physics Graduate Program. The LSU-MBPCC Program graduates approximately six students yearly, which equates to a need for up to twelve residency positions in a two-year program. To address this need for residency positions, MBPCC has expanded its Program by developing a Consortium consisting of partnerships with medical physics groups located at other nearby clinical institutions. The consortium model offers the residents exposure to a broader range of procedures, technology, and faculty than available at the individual institutions. The Consortium institutions have shown a great deal of support from their medical physics groups and administrations in developing these partnerships. Details of these partnerships are specified within affiliation agreements between MBPCC and each participating institution. All partner sites began resident training in 2011. The Consortium is a network of for-profit, nonprofit, academic, community, and private entities. We feel that these types of collaborative endeavors will be required nationally to reach the number of residency positions needed to meet the 2014 ABR certification requirements and to maintain graduate medical physics training programs.

  7. Health Coaching: An Update on the National Consortium for Credentialing of Health & Wellness Coaches

    OpenAIRE

    Mittelman, Michele

    2015-01-01

    In September 2014, Global Advances in Health and Medicine editor Michele Mittelman, RN, MPH, interviewed four of the leaders in health and wellness coaching about trends in coaching and the progress of the National Consortium for Credentialing of Health & Wellness Coaches. Following are the transcripts of those interviews. Additionally, videos of the interviews are available at www.gahmj.com.

  8. RSC Classroom Research Consortium Project: 1990-91/Year-Two Report.

    Science.gov (United States)

    Anthony, Mary Anne

    In 1989, a consortium of four community colleges in Southern California (i.e., Cerritos College, Mt. San Antonio College, Rancho Santiago College, and Rio Hondo College) received a Title III grant of $2.5 million to support the development of innovative teaching and learning programs. The specific goals of the project are to increase the academic…

  9. The Georgia Higher Education Consortium: A Model for Linking Early Intervention Faculty.

    Science.gov (United States)

    Gallagher, Peggy A.; Vail, Cynthia O.; McCormick, Katherine; Malone, D. Michael

    2001-01-01

    A higher education consortium (HEC) in early intervention (EI) is described. An evaluation of the model found that benefits to faculty of HEC participation included development and implementation of EI coursework, development of interdisciplinary collaborative relationships, increased knowledge of state resources, and enhanced knowledge of EI…

  10. Nursing Faculty Collaborate with Embedded Librarians to Serve Online Graduate Students in a Consortium Setting

    Science.gov (United States)

    Guillot, Ladonna; Stahr, Beth; Meeker, Bonnie Juve'

    2010-01-01

    Nursing and library faculty face many information literacy challenges when graduate nursing programs migrate to online course delivery. The authors describe a collaborative model for providing cost-effective online library services to new graduate students in a three-university consortium. The embedded librarian service links a health sciences…

  11. Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.

    Science.gov (United States)

    Green, Robert C; Goddard, Katrina A B; Jarvik, Gail P; Amendola, Laura M; Appelbaum, Paul S; Berg, Jonathan S; Bernhardt, Barbara A; Biesecker, Leslie G; Biswas, Sawona; Blout, Carrie L; Bowling, Kevin M; Brothers, Kyle B; Burke, Wylie; Caga-Anan, Charlisse F; Chinnaiyan, Arul M; Chung, Wendy K; Clayton, Ellen W; Cooper, Gregory M; East, Kelly; Evans, James P; Fullerton, Stephanie M; Garraway, Levi A; Garrett, Jeremy R; Gray, Stacy W; Henderson, Gail E; Hindorff, Lucia A; Holm, Ingrid A; Lewis, Michelle Huckaby; Hutter, Carolyn M; Janne, Pasi A; Joffe, Steven; Kaufman, David; Knoppers, Bartha M; Koenig, Barbara A; Krantz, Ian D; Manolio, Teri A; McCullough, Laurence; McEwen, Jean; McGuire, Amy; Muzny, Donna; Myers, Richard M; Nickerson, Deborah A; Ou, Jeffrey; Parsons, Donald W; Petersen, Gloria M; Plon, Sharon E; Rehm, Heidi L; Roberts, J Scott; Robinson, Dan; Salama, Joseph S; Scollon, Sarah; Sharp, Richard R; Shirts, Brian; Spinner, Nancy B; Tabor, Holly K; Tarczy-Hornoch, Peter; Veenstra, David L; Wagle, Nikhil; Weck, Karen; Wilfond, Benjamin S; Wilhelmsen, Kirk; Wolf, Susan M; Wynn, Julia; Yu, Joon-Ho

    2016-06-01

    Despite rapid technical progress and demonstrable effectiveness for some types of diagnosis and therapy, much remains to be learned about clinical genome and exome sequencing (CGES) and its role within the practice of medicine. The Clinical Sequencing Exploratory Research (CSER) consortium includes 18 extramural research projects, one National Human Genome Research Institute (NHGRI) intramural project, and a coordinating center funded by the NHGRI and National Cancer Institute. The consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has thus far recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing. The CSER consortium is analyzing data and creating publically available procedures and tools related to participant preferences and consent, variant classification, disclosure and management of primary and secondary findings, health outcomes, and integration with electronic health records. Future research directions will refine measures of clinical utility of CGES in both germline and somatic testing, evaluate the use of CGES for screening in healthy individuals, explore the penetrance of pathogenic variants through extensive phenotyping, reduce discordances in public databases of genes and variants, examine social and ethnic disparities in the provision of genomics services, explore regulatory issues, and estimate the value and downstream costs of sequencing. The CSER consortium has established a shared community of research sites by using diverse approaches to pursue the evidence-based development of best practices in genomic medicine. PMID:27181682

  12. African-Caribbean cancer consortium for the study of viral, genetic and environmental cancer risk factors

    Directory of Open Access Journals (Sweden)

    Odedina Folakemi

    2007-09-01

    Full Text Available Abstract This is a short summary of a meeting of the "African-Caribbean Cancer Consortium", jointly organized by the University of Pittsburgh, Department of Epidemiology and the University of Pittsburgh Cancer Institute, held in Montego Bay, Jamaica as a satellite meeting at the Caribbean Health Research Council, 52nd Annual Council and Scientific meeting on May 4, 2007.

  13. Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine.

    Science.gov (United States)

    Green, Robert C; Goddard, Katrina A B; Jarvik, Gail P; Amendola, Laura M; Appelbaum, Paul S; Berg, Jonathan S; Bernhardt, Barbara A; Biesecker, Leslie G; Biswas, Sawona; Blout, Carrie L; Bowling, Kevin M; Brothers, Kyle B; Burke, Wylie; Caga-Anan, Charlisse F; Chinnaiyan, Arul M; Chung, Wendy K; Clayton, Ellen W; Cooper, Gregory M; East, Kelly; Evans, James P; Fullerton, Stephanie M; Garraway, Levi A; Garrett, Jeremy R; Gray, Stacy W; Henderson, Gail E; Hindorff, Lucia A; Holm, Ingrid A; Lewis, Michelle Huckaby; Hutter, Carolyn M; Janne, Pasi A; Joffe, Steven; Kaufman, David; Knoppers, Bartha M; Koenig, Barbara A; Krantz, Ian D; Manolio, Teri A; McCullough, Laurence; McEwen, Jean; McGuire, Amy; Muzny, Donna; Myers, Richard M; Nickerson, Deborah A; Ou, Jeffrey; Parsons, Donald W; Petersen, Gloria M; Plon, Sharon E; Rehm, Heidi L; Roberts, J Scott; Robinson, Dan; Salama, Joseph S; Scollon, Sarah; Sharp, Richard R; Shirts, Brian; Spinner, Nancy B; Tabor, Holly K; Tarczy-Hornoch, Peter; Veenstra, David L; Wagle, Nikhil; Weck, Karen; Wilfond, Benjamin S; Wilhelmsen, Kirk; Wolf, Susan M; Wynn, Julia; Yu, Joon-Ho

    2016-06-01

    Despite rapid technical progress and demonstrable effectiveness for some types of diagnosis and therapy, much remains to be learned about clinical genome and exome sequencing (CGES) and its role within the practice of medicine. The Clinical Sequencing Exploratory Research (CSER) consortium includes 18 extramural research projects, one National Human Genome Research Institute (NHGRI) intramural project, and a coordinating center funded by the NHGRI and National Cancer Institute. The consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has thus far recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing. The CSER consortium is analyzing data and creating publically available procedures and tools related to participant preferences and consent, variant classification, disclosure and management of primary and secondary findings, health outcomes, and integration with electronic health records. Future research directions will refine measures of clinical utility of CGES in both germline and somatic testing, evaluate the use of CGES for screening in healthy individuals, explore the penetrance of pathogenic variants through extensive phenotyping, reduce discordances in public databases of genes and variants, examine social and ethnic disparities in the provision of genomics services, explore regulatory issues, and estimate the value and downstream costs of sequencing. The CSER consortium has established a shared community of research sites by using diverse approaches to pursue the evidence-based development of best practices in genomic medicine.

  14. Genome Consortium for Active Teaching: Meeting the Goals of BIO2010

    Science.gov (United States)

    Campbell, A. Malcolm; Ledbetter, Mary Lee S.; Hoopes, Laura L. M.; Eckdahl, Todd T.; Heyer, Laurie J.; Rosenwald, Anne; Fowlks, Edison; Tonidandel, Scott; Bucholtz, Brooke; Gottfried, Gail

    2007-01-01

    The Genome Consortium for Active Teaching (GCAT) facilitates the use of modern genomics methods in undergraduate education. Initially focused on microarray technology, but with an eye toward diversification, GCAT is a community working to improve the education of tomorrow's life science professionals. GCAT participants have access to affordable…

  15. Bioremediation of crude oil waste contaminated soil using petrophilic consortium and Azotobacter sp.

    Directory of Open Access Journals (Sweden)

    M. Fauzi

    2016-01-01

    Full Text Available This study was aimed to determine the effect Petrophilic and Azotobacter sp. consortium on the rate of degradation of hydrocarbons, Azotobacter growth, and Petrophilic fungi growth in an Inceptisol contaminated with crude oil waste originating from Balongan refinery, one of Pertamina (Indonesia’s largest state-owned oil and gas company units in Indramayu – West Java. This study was conducted from March to April 2014 in the glasshouse of research station of the Faculty of Agriculture, Padjadjaran University at Ciparanje, Jatinangor District, Sumedang Regency of West Java. This study used a factorial completely randomized design with two treatments. The first treatment factor was Petrophilic microbes (A consisting of four levels (without treatment, 2% Petrophilic fungi, 2% Petrophilic bacteria, and the 2% Petrophilic consortium, and Azotobacter sp. The second treatment factor was Azotobacter sp. (B consisting of four levels (without treatment, 0.5%, Azotobacter sp., 1% Azotobacter sp., and 1.5% Azotobacter sp. The results demonstrated interaction between Petrophilic microbes and Azotobacter sp. towards hydrocarbon degradation rate, but no interaction was found towards the growth rate of Azotobacter sp. and Petrophilic fungi. Treatments of a1b3 (2% consortium of Petrophilic fungi with 1.5% Azotobacter sp. and a3b3 (2% Petrophilic consortium and 1.5% Azotobacter sp. had hydrocarbon degradation rate at 0.22 ppm/day for each treatment, showing the highest hydrocarbon degradation rate.

  16. Biological Removal of Phosphate Using Phosphate Solubilizing Bacterial Consortium from Synthetic Wastewater: A Laboratory Scale

    Directory of Open Access Journals (Sweden)

    Dipak Paul

    2015-01-01

    Full Text Available Biological phosphate removal is an important process having gained worldwide attention and widely used for removing phosphorus from wastewater. The present investigation was aimed to screen the efficient phosphate solubilizing bacterial isolates and used to remove phosphate from synthetic wastewater under shaking flasks conditions. Pseudomonas sp. JPSB12, Enterobacter sp. TPSB20, Flavobacterium sp. TPSB23 and mixed bacterial consortium (Pseudomonas sp. JPSB12+Enterobacter sp. TPSB20+Flavobacterium sp. TPSB23 were used for the removal of phosphate. Among the individual strains, Enterobacter sp. TPSB20 was removed maximum phosphate (61.75% from synthetic wastewater in presence of glucose as a carbon source. The consortium was effectively removed phosphate (74.15-82.50% in the synthetic wastewater when compared to individual strains. The pH changes in culture medium with time and extracellular phosphatase activity (acid and alkaline were also investigated. The efficient removal of phosphate by the consortium may be due to the synergistic activity among the individual strains and phosphatase enzyme activity. The use of bacterial consortium in the remediation of phosphate contaminated aquatic environments has been discussed.

  17. 78 FR 79613 - Final Requirement-Migrant Education Program Consortium Incentive Grant Program

    Science.gov (United States)

    2013-12-31

    ... Federal Register on July 3, 2013 (78 FR 40084). That notice contained background information and our... Federal Register on March 3, 2004 (69 FR 10110). The second and third year's continuation funding is... CFR Chapter II Final Requirement--Migrant Education Program Consortium Incentive Grant Program...

  18. 78 FR 40084 - Proposed Requirement-Migrant Education Program Consortium Incentive Grant Program

    Science.gov (United States)

    2013-07-03

    ... Register on March 3, 2004 (69 FR 10110) (2004 Notice), and we have used these final requirements for CIG... final priority for the MEP CIG program in the Federal Register on March 12, 2008 (73 FR 13217), in which... CFR Chapter II Proposed Requirement--Migrant Education Program Consortium Incentive Grant...

  19. LBL/JSU/AGMUS science consortium annual report, FY 1991--1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    In 1983, a formal Memorandum of Understanding joined the Ana G. Mendez University System (AGMUS), Jackson State University (JSU), and the Lawrence Berkeley Laboratory (LBL) in a consortium designed to advance the science and technology programs of JSU and AGMUS. This is the first such collaboration between a Hispanic university system, a historically Black university, and a national laboratory. The goals of this alliance are basic and direct: to develop and effect a long-term, comprehensive program that will enable the campuses of AGMUS and JSU to provide a broad, high-quality offering in the natural and computer sciences, to increase the number of minority students entering these fields, and to contribute to scientific knowledge and the federal government`s science mission through research. This report documents the progress toward these goals and includes individual success stories. The LBL/JSU/AGMUS Science Consortium has developed plans for utilizing its program successes to help other institutions to adopt or adapt those elements of the model that have produced the greatest results. Within the five-year plan formulated in 1990 are eight major components, each with defining elements and goals. These elements have become the components of the Science Consortium`s current plan for expansion and propagation.

  20. Academically Ambitious and Relevant Higher Education Research: The Legacy of the Consortium of Higher Education Researchers

    Science.gov (United States)

    Teichler, Ulrich

    2013-01-01

    The Consortium of Higher Education Researchers (CHER) was founded in 1988 to stimulate international communication and collaboration of higher education researchers. A need was felt to offset the isolation of the small numbers of scholars in this area of expertise in many countries, as well as the isolation of individual disciplines addressing…

  1. Customer Satisfaction Perceptions of Dislocated Workers Served by WIN Job Centers in the Mississippi Corridor Consortium

    Science.gov (United States)

    Washburn, Dava Michelle

    2009-01-01

    The purpose of this study was to determine the perceptions of satisfaction of dislocated workers served by WIN Job Centers in the Mississippi Corridor Consortium. Four WIN Job Centers participated in this study: Northeast Mississippi Community College WIN Job Center in Corinth, Northwest Mississippi Community College WIN Job Center in Oxford,…

  2. Consolidated Bio-Processing of Cellulosic Biomass for Efficient Biofuel Production Using Yeast Consortium

    Science.gov (United States)

    Goyal, Garima

    Fossil fuels have been the major source for liquid transportation fuels for ages. However, decline in oil reserves and environmental concerns have raised a lot of interest in alternative and renewable energy sources. One promising alternative is the conversion of plant biomass into ethanol. The primary biomass feed stocks currently being used for the ethanol industry have been food based biomass (corn and sugar cane). However, interest has recently shifted to replace these traditional feed-stocks with more abundant, non-food based cellulosic biomass such as agriculture wastes (corn stover) or crops (switch grass). The use of cellulosic biomass as feed stock for the production of ethanol via bio-chemical routes presents many technical challenges not faced with the use of corn or sugar-cane as feed-stock. Recently, a new process called consolidated Bio-processing (CBP) has been proposed. This process combines simultaneous saccharification of lignocellulose with fermentation of the resulting sugars into a single process step mediated by a single microorganism or microbial consortium. Although there is no natural microorganism that possesses all properties of lignocellulose utilization and ethanol production desired for CBP, some bacteria and fungi exhibit some of the essential traits. The yeast Saccharomyces cerevisiae is the most attractive host organism for the usage of this strategy due to its high ethanol productivity at close to theoretical yields (0.51g ethanol/g glucose consumed), high osmo- and ethanol- tolerance, natural robustness in industrial processes, and ease of genetic manipulation. Introduction of the cellulosome, found naturally in microorganisms, has shown new directions to deal with recalcitrant biomass. In this case enzymes work in synergy in order to hydrolyze biomass more effectively than in case of free enzymes. A microbial consortium has been successfully developed, which ensures the functional assembly of minicellulosome on the yeast surface

  3. A Fungal-Prokaryotic Consortium at the Basalt-Zeolite Interface in Subseafloor Igneous Crust.

    Directory of Open Access Journals (Sweden)

    Magnus Ivarsson

    Full Text Available We have after half a century of coordinated scientific drilling gained insight into Earth´s largest microbial habitat, the subseafloor igneous crust, but still lack substantial understanding regarding its abundance, diversity and ecology. Here we describe a fossilized microbial consortium of prokaryotes and fungi at the basalt-zeolite interface of fractured subseafloor basalts from a depth of 240 m below seafloor (mbsf. The microbial consortium and its relationship with the surrounding physical environment are revealed by synchrotron-based X-ray tomographic microscopy (SRXTM, environmental scanning electron microscopy (ESEM, and Raman spectroscopy. The base of the consortium is represented by microstromatolites-remains of bacterial communities that oxidized reduced iron directly from the basalt. The microstromatolites and the surrounding basalt were overlaid by fungal cells and hyphae. The consortium was overgrown by hydrothermally formed zeolites but remained alive and active during this event. After its formation, fungal hyphae bored in the zeolite, producing millimetre-long tunnels through the mineral substrate. The dissolution could either serve to extract metals like Ca, Na and K essential for fungal growth and metabolism, or be a response to environmental stress owing to the mineral overgrowth. Our results show how microbial life may be maintained in a nutrient-poor and extreme environment by close ecological interplay and reveal an effective strategy for nutrient extraction from minerals. The prokaryotic portion of the consortium served as a carbon source for the eukaryotic portion. Such an approach may be a prerequisite for prokaryotic-eukaryotic colonisation of, and persistence in, subseafloor igneous crust.

  4. A Fungal-Prokaryotic Consortium at the Basalt-Zeolite Interface in Subseafloor Igneous Crust.

    Science.gov (United States)

    Ivarsson, Magnus; Bengtson, Stefan; Skogby, Henrik; Lazor, Peter; Broman, Curt; Belivanova, Veneta; Marone, Federica

    2015-01-01

    We have after half a century of coordinated scientific drilling gained insight into Earth´s largest microbial habitat, the subseafloor igneous crust, but still lack substantial understanding regarding its abundance, diversity and ecology. Here we describe a fossilized microbial consortium of prokaryotes and fungi at the basalt-zeolite interface of fractured subseafloor basalts from a depth of 240 m below seafloor (mbsf). The microbial consortium and its relationship with the surrounding physical environment are revealed by synchrotron-based X-ray tomographic microscopy (SRXTM), environmental scanning electron microscopy (ESEM), and Raman spectroscopy. The base of the consortium is represented by microstromatolites-remains of bacterial communities that oxidized reduced iron directly from the basalt. The microstromatolites and the surrounding basalt were overlaid by fungal cells and hyphae. The consortium was overgrown by hydrothermally formed zeolites but remained alive and active during this event. After its formation, fungal hyphae bored in the zeolite, producing millimetre-long tunnels through the mineral substrate. The dissolution could either serve to extract metals like Ca, Na and K essential for fungal growth and metabolism, or be a response to environmental stress owing to the mineral overgrowth. Our results show how microbial life may be maintained in a nutrient-poor and extreme environment by close ecological interplay and reveal an effective strategy for nutrient extraction from minerals. The prokaryotic portion of the consortium served as a carbon source for the eukaryotic portion. Such an approach may be a prerequisite for prokaryotic-eukaryotic colonisation of, and persistence in, subseafloor igneous crust.

  5. Biodegradation of polycyclic aromatic hydrocarbons by a bacterial consortium enriched from mangrove sediments.

    Science.gov (United States)

    Shahriari Moghadam, Mohsen; Ebrahimipour, Gholamhossein; Abtahi, Behrooz; Ghassempour, Alireza; Hashtroudi, Mehri Seyed

    2014-01-01

    Polycyclic aromatic hydrocarbons (PAHs) biodegradation in contaminated sediment is an attractive remediation technique and its success depends on the optimal condition for the PAH-degrading isolates. The aims of the current study was to isolate and identify PAHs-degrading bacteria from surface sediments of Nayband Bay and to evaluate the efficiency of statistically based experimental design for the optimization of phenanthrene (Phe) and Fluorene (Flu) biodegradation performed by enriched consortium. PAHs degrading bacteria were isolated from surface sediments. Purified strains were then identified by 16S rDNA gene sequence analysis. Taguchi L16 (4(5)) was employed to evaluate the optimum biodegradation of Phe and Flu by the enriched consortium. Total of six gram-negative bacterial strains including Marinobacter hydrocarbonoclasticus, Roseovarius pacificus, Pseudidiomarina sediminum and 3 unidentified strains were isolated from enrichment consortium, using Fluorene (Flu) and phenanthrene (Phe) as the sole carbon and energy source. The enriched consortium showed highest degradation abilities (64.0% Flu and 58.4% Phe degraded in 7 days) in comparison to a single strain cultures or mixtures. Maximum biodegradation efficiency was occur at temperature = 35°C; pH = 8; inoculum size = 0. 4 OD600nm; salinity = 40 ppt; C/N ratio = 100:10. In conclusion our results showed that, indigenous bacteria from mangrove surface sediments of Nayband Bay have high potential to degrade Flu and Phe with the best results achieved when enriched consortium was used. PMID:25436114

  6. Enhanced decolorization and biodegradation of textile azo dye Scarlet R by using developed microbial consortium-GR.

    Science.gov (United States)

    Saratale, R G; Saratale, G D; Kalyani, D C; Chang, J S; Govindwar, S P

    2009-05-01

    A developed consortium-GR, consisting of Proteus vulgaris NCIM-2027 (PV) and Micrococcus glutamicus NCIM-2168 (MG), completely decolorized an azo dye Scarlet R under static anoxic condition with an average decolorization rate of 16,666 microg h(-1); which is much faster than that of the pure cultures (PV, 3571 microg h(-1); MG, 2500 microg h(-1)). Consortium-GR gave best decolorization performance with nearly complete mineralization of Scarlet R (over 90% TOC and COD reduction) within 3h, much shorter relative to the individual strains. Induction in the riboflavin reductase and NADH-DCIP reductase was observed in the consortium, suggesting the involvement of these enzymes during the fast decolorization process. The FTIR and GC-MS analysis showed that 1,4-benzenediamine was formed during decolorization/degradation of Scarlet R by consortium-GR. Phytotoxicity studies revealed no toxicity of the biodegraded products of Scarlet R by consortium-GR. In addition, consortium-GR applied for mixture of industrial dyes showed 88% decolorization under static condition with significant reduction in TOC (62%) and COD (68%) within 72 h, suggesting potential application of this microbial consortium in bioremediation of dye-containing wastewater.

  7. Biodegradation of phenanthrene in bioaugmented microcosm by consortium ASP developed from coastal sediment of Alang-Sosiya ship breaking yard.

    Science.gov (United States)

    Patel, Vilas; Patel, Janki; Madamwar, Datta

    2013-09-15

    A phenanthrene-degrading bacterial consortium (ASP) was developed using sediment from the Alang-Sosiya shipbreaking yard at Gujarat, India. 16S rRNA gene-based molecular analyses revealed that the bacterial consortium consisted of six bacterial strains: Bacillus sp. ASP1, Pseudomonas sp. ASP2, Stenotrophomonas maltophilia strain ASP3, Staphylococcus sp. ASP4, Geobacillus sp. ASP5 and Alcaligenes sp. ASP6. The consortium was able to degrade 300 ppm of phenanthrene and 1000 ppm of naphthalene within 120 h and 48 h, respectively. Tween 80 showed a positive effect on phenanthrene degradation. The consortium was able to consume maximum phenanthrene at the rate of 46 mg/h/l and degrade phenanthrene in the presence of other petroleum hydrocarbons. A microcosm study was conducted to test the consortium's bioremediation potential. Phenanthrene degradation increased from 61% to 94% in sediment bioaugmented with the consortium. Simultaneously, bacterial counts and dehydrogenase activities also increased in the bioaugmented sediment. These results suggest that microbial consortium bioaugmentation may be a promising technology for bioremediation.

  8. Dissimilatory reduction of perchlorate and other common pollutants by a consortium enriched from tidal flats of the Yellow Sea

    Institute of Scientific and Technical Information of China (English)

    Nirmala Bardiya; Jae-Ho Bae

    2015-01-01

    Objective: To enrich a facultative anaerobic bacterial consortium from the Yellow Sea and assess its ability to reduce perchlorate and other co-pollutants. Methods: Bacterial consortium collected from the tidal flats of the Yellow Sea was enriched in an anoxic medium containing perchlorate as the electron (e-) acceptor and acetate as the electron (e-) donor. The enriched consortium was then tested for perchlorate reduction under different perchlorate concentrations and in the presence of nitrate by using standard anaerobic techniques. The complete enzymatic reduction of perchlorate to chloride was confirmed by chlorite dismutation. Ability of the consortium to grow with alternate e- acceptors was also tested with acetate as the e- donor. Results: The enriched consortium could rapidly reduce perchlorate up to the initial concentration of 25.65 mmol/L. In the presence of nitrate, perchlorate reduction did not occur immediately and reduction of nitrate started after a lag phase, with concomitant accumulation of nitrite. The perchlorate-enriched consortium could reduce chlorate, oxygen, Cr (VI), and selenate as the alternate e- acceptors but failed to utilize sulfate, thiosulfate, sulfite, and nitrite. Conclusions: The consortium from the tidal flats of the Yellow Sea could reduce perchlorate and co-contaminants such as chlorate, nitrate, Cr (VI), and selenate under heterotrophic conditions with acetate as the e- donor and carbon source. While perchlorate was completely dismutated into innocuous chloride and oxygen, accumulation of nitrite occurred during the reduction of nitrate.

  9. Optimization and kinetics evaluation of biodegradation of synthetic azo reactive dye by fungal consortium.

    Science.gov (United States)

    Chitradevi, V; Sivakumar, V

    2011-10-01

    Wastewater containing direct dyes discharged from various industries, in particular, textile industry, often cause many environmental problems. Among the various effluent treatment methods, biological methods found to be cost effective and do not end up in secondary pollutants. In this study, an attempt has been made to study the decolorization of cibacron yellow S-3R, an azo reactive dye by using fungal cultures such as Coriolus versicolor, Phanerochaete chrysosporium, Pleurotus ostreatus, and Myrothecium verrucaria. The fungi were able to decolorize individually the azo reactive dye cibacron yellow S-3R to an extent of nearly in the range 75 - 85%, whereas the mixed fungal consortium was able to decolorize to an extent of nearly 95%.The study is extended with the kinetics of decolorization of Cibacron yellow S-3R using mixed fungal consortium containing equal proportions of the cultures. The experimental results show that decolorization kinetics follow second order rate equation.

  10. A stable synergistic microbial consortium for simultaneous azo dye removal and bioelectricity generation.

    Science.gov (United States)

    Wang, Victor Bochuan; Chua, Song-Lin; Cai, Zhao; Sivakumar, Krishnakumar; Zhang, Qichun; Kjelleberg, Staffan; Cao, Bin; Loo, Say Chye Joachim; Yang, Liang

    2014-03-01

    Microbial species coexist in natural or engineered settings, where they encounter extensive competition and cooperation. Interactions occurring through metabolite exchange or direct contact might be important in establishment of functional biodegradation consortium. Understanding these interactions can facilitate manipulation of selected communities and exploitation of their capacity for specific industrial applications. Here, a simple dual-species consortium (Pseudomonas putida and Shewanella oneidensis) was established for examining simultaneous Congo red bioremediation in planktonic culture and power generation in anode biofilms. Compared to mono-species cultures, co-cultures generated higher current densities and could concurrently degrade Congo red over 72h. Disabling the large secreted adhesion protein, LapA, of P. putida greatly enhanced S. oneidensis biofilm formation on the anode, which increased power generation in co-cultures. This demonstrates simultaneous control of specific planktonic and biofilm communities could be effective in manipulating microbial communities for targeted applications.

  11. Ohio Coal Research Consortium fifth year final reports summary, September 1, 1994--February 29, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    As part of its efforts to improve the use of high-sulfur Ohio coal within environmental limits, the Ohio Coal Development Office, an entity within the Ohio Department of Development (OCDO/ODOD), in late 1988 established a consortium of four Ohio universities. The purpose of the Ohio Coal Research Consortium is to conduct a multi-year fundamental research programs focused on: (1) the enhancement or development of dry sorption processes for the economical removal of high levels of SO{sub 2} and other pollutants, and (2) an increased understanding of methods for reduction in air toxics emissions from combustion gases produced by burning high-sulfur Ohio coal. This report contains summaries of eleven studies in these areas.

  12. Ohio Coal Research Consortium fourth year final summary report, September 1, 1993--August 31, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    As a part of its efforts to improve the use of high-sulfur Ohio coal within environmental limits, the Ohio Coal Development Office, an entity within the Ohio Department of Development (OCDO/ODOD), in late 1988 established a consortium of four Ohio universities. The purpose of the Ohio Coal Research Consortium is to conduct a multi-year fundamental research program focused on (1) the enhancement or development of dry sorption processes for the economical removal of high levels of SO{sub 2} and other pollutants and (2) an increased understanding of methods for reduction in air toxics emissions from combustion gases produced by burning high-sulfur Ohio coal. This report contains summaries of twelve studies in these areas.

  13. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

    DEFF Research Database (Denmark)

    Freschi, Luca; Jeukens, Julie; Kukavica-Ibrulj, Irena;

    2015-01-01

    The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are a...... implicated in human and animal infections, understand how patients become infected and how the infection evolves over time as well as identify prognostic markers for better evidence-based decisions on patient care.......The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection...

  14. Microbial Consortium with High Cellulolytic Activity (MCHCA for enhanced biogas production.

    Directory of Open Access Journals (Sweden)

    Krzysztof ePoszytek

    2016-03-01

    Full Text Available The use of lignocellulosic biomass as a substrate in agricultural biogas plants is very popular and yields good results. However, the efficiency of anaerobic digestion, and thus biogas production, is not always satisfactory due to the slow or incomplete degradation (hydrolysis of plant matter. To enhance the solubilization of the lignocellulosic biomass various physical, chemical and biological pretreatment methods are used.The aim of this study was to select and characterize cellulose-degrading bacteria, and to construct a microbial consortium, dedicated for degradation of maize silage and enhancing biogas production from this substrate.Over one hundred strains of cellulose-degrading bacteria were isolated from: sewage sludge, hydrolyzer from an agricultural biogas plant, cattle slurry and manure. After physiological characterization of the isolates, sixteen strains (representatives of Bacillus, Providencia and Ochrobactrum genera were chosen for the construction of a Microbial Consortium with High Cellulolytic Activity, called MCHCA. The selected strains had a high endoglucanase activity (exceeding 0.21 IU/mL CMCase activity and a wide range of tolerance to various physical and chemical conditions. Lab-scale simulation of biogas production using the selected strains for degradation of maize silage was carried out in a two-bioreactor system, similar to those used in agricultural biogas plants.The obtained results showed that the constructed MCHCA consortium is capable of efficient hydrolysis of maize silage, and increases biogas production by even 38%, depending on the inoculum used for methane fermentation. The results in this work indicate that the mesophilic Microbial Consortium with High Cellulolytic Activity has a great potential for application on industrial scale in agricultural biogas plants.

  15. Biological Removal of Phosphate Using Phosphate Solubilizing Bacterial Consortium from Synthetic Wastewater: A Laboratory Scale

    OpenAIRE

    Dipak Paul; Sankar Narayan Sinha

    2015-01-01

    Biological phosphate removal is an important process having gained worldwide attention and widely used for removing phosphorus from wastewater. The present investigation was aimed to screen the efficient phosphate solubilizing bacterial isolates and used to remove phosphate from synthetic wastewater under shaking flasks conditions. Pseudomonas sp. JPSB12, Enterobacter sp. TPSB20, Flavobacterium sp. TPSB23 and mixed bacterial consortium (Pseudomonas sp. JPSB12+Enterobacter sp. TPSB20+Flavobact...

  16. The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping

    OpenAIRE

    Steve D M Brown; Moore, Mark W.

    2012-01-01

    Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse ...

  17. Global Assessment of Hydrogen Technologies – Task 6 Report Promoting a Southeast Hydrogen Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Fouad, Fouad H.; Peters, Robert W.; Sisiopiku, Virginia P.; Sullivan Andrew J.

    2007-12-01

    The purpose of this project task was to establish a technical consortium to promote the deployment of hydrogen technologies and infrastructure in the Southeast. The goal was to partner with fuel cell manufacturers, hydrogen fuel infrastructure providers, electric utilities, energy service companies, research institutions, and user groups to improve education and awareness of hydrogen technologies in an area that is lagging behind other parts of the country in terms of vehicle and infrastructure demonstrations and deployments. This report documents that effort.

  18. Development of an Efficient Bacterial Consortium for the Potential Remediation of Hydrocarbons from Contaminated Sites.

    Science.gov (United States)

    Patowary, Kaustuvmani; Patowary, Rupshikha; Kalita, Mohan C; Deka, Suresh

    2016-01-01

    The intrinsic biodegradability of hydrocarbons and the distribution of proficient degrading microorganisms in the environment are very crucial for the implementation of bioremediation practices. Among others, one of the most favorable methods that can enhance the effectiveness of bioremediation of hydrocarbon-contaminated environment is the application of biosurfactant producing microbes. In the present study, the biodegradation capacities of native bacterial consortia toward total petroleum hydrocarbons (TPH) with special emphasis to poly aromatic hydrocarbons were determined. The purpose of the study was to isolate TPH degrading bacterial strains from various petroleum contaminated soil of Assam, India and develop a robust bacterial consortium for bioremediation of crude oil of this native land. From a total of 23 bacterial isolates obtained from three different hydrocarbons contaminated samples five isolates, namely KS2, PG1, PG5, R1, and R2 were selected as efficient crude oil degraders with respect to their growth on crude oil enriched samples. Isolates KS2, PG1, and R2 are biosurfactant producers and PG5, R1 are non-producers. Fourteen different consortia were designed involving both biosurfactant producing and non-producing isolates. Consortium 10, which comprises two Bacillus strains namely, Bacillus pumilus KS2 and B. cereus R2 (identified by 16s rRNA sequencing) has shown the best result in the desired degradation of crude oil. The consortium showed degradation up to 84.15% of TPH after 5 weeks of incubation, as revealed from gravimetric analysis. FTIR (Fourier transform infrared) and GCMS (Gas chromatography-mass spectrometer) analyses were correlated with gravimetric data which reveals that the consortium has removed a wide range of petroleum hydrocarbons in comparison with abiotic control including different aliphatic and aromatic hydrocarbons. PMID:27471499

  19. Obesity and risk of ovarian cancer subtypes: evidence from the Ovarian Cancer Association Consortium

    OpenAIRE

    Olsen, C. M.; Nagle, C. M.; Whiteman, D C; Ness, R; C. L. Pearce; Pike, M. C.; Rossing, M A; Terry, Kathryn Lynne; Wu, A. H.; Risch, H A; Yu, H.; Doherty, J. A.; Chang-Claude, J; Hein, R.; Nickels, S

    2013-01-01

    Whilst previous studies have reported that higher body-mass index (BMI) increases a woman’s risk of developing ovarian cancer, associations for the different histological subtypes have not been well defined. As the prevalence of obesity has increased dramatically, and classification of ovarian histology has improved in the last decade, we sought to examine the association in a pooled analysis of recent studies participating in the Ovarian Cancer Association Consortium. We ev...

  20. Evaluation of whey fermented by Enterococcus faecium in consortium with Veilonella parvula in ruminant feeding

    OpenAIRE

    Juliana Silva de Oliveira; Augusto César de Queiroz; Hilário Cuquetto Mantovani; Geraldo Fábio Viana Bayão; Edenio Detmann; Edson Mauro Santos; Thiago Carvalho da Silva

    2012-01-01

    The objective of this study was to evaluate the whey fermented by Enterococcus faecium in consortium with Veilonella parvula on the in vitro growth of ruminal bacteria and as a supplement in the cattle diet. In the in vitro experiment, a randomized design, with the following combinations was used: ruminal bacteria; ruminal bacteria and inactive whey; ruminal bacteria and active whey; and active whey. In the in vivo experiment, five fistulated Zebu Holstein-Zebu crossbred heifers were distribu...

  1. Effect of whey fermented by Enterococcus faeciumin consortium with Veilonella parvulaon ruminal bacteria in vitro

    OpenAIRE

    Higor Fábio Carvalho Bezerra; Juliana Silva de Oliveira; Edson Mauro Santos; Augusto César de Queiroz; Hilário Cuquetto Mantovani; Ricardo Martins Araujo Pinho; Jurandir Queiroz de Oliveira Junior; Elizabete Cristina Batista da Costa

    2014-01-01

    The objective of this research was to evaluate the effect of whey fermented by Enterococus faecium in consortium with Veilonella parvula in vitro on ruminal microorganisms in different substrates, with or without monensin. The first experiment was carried out in a completely randomized design, in a 6 × 3 factorial arrangement (six substrates × three whey levels) with two replicates. In experiment two, a 2 × 3 × 4 factorial arrangement (with and without monensin, three foods and four levels of...

  2. Determining client need in a multi-state fetal alcohol syndrome consortium: from training to practice

    OpenAIRE

    Haynes George; Dunnagan Tim; Christopher Suzanne; Stiff Lili

    2007-01-01

    Abstract Background A multi-state consortium was developed in the US to conduct baseline data collection and intervention research on fetal alcohol syndrome. Each state employed support specialists whose job it was to reduce or eliminate alcohol consumption in women who were at high risk for drinking alcohol during their pregnancy. The purpose of this paper is to report how support specialists in three primarily rural/frontier states were trained to assess client need and how client need was ...

  3. Development of an efficient bacterial consortium for the potential remediation of hydrocarbons from contaminated sites

    Directory of Open Access Journals (Sweden)

    Kaustuvmani Patowary

    2016-07-01

    Full Text Available The intrinsic biodegradability of hydrocarbons and the distribution of proficient degrading microorganisms in the environment are very crucial for the implementation of bioremediation practices. Among others, one of the most favorable methods that can enhance the effectiveness of bioremediation of hydrocarbon-contaminated environment is the application of biosurfactant producing microbes. In the present study, the biodegradation capacities of native bacterial consortia towards total petroleum hydrocarbons (TPH with special emphasis to poly aromatic hydrocarbons (PAHs were determined. The purpose of the study was to isolate TPH degrading bacterial strains from various petroleum contaminated soil of Assam, India and develop a robust bacterial consortium for bioremediation of crude oil of this native land. From a total of 23 bacterial isolates obtained from three different hydrocarbons contaminated samples 5 isolates, namely KS2, PG1, PG5, R1 and R2 were selected as efficient crude oil degraders with respect to their growth on crude oil enriched samples. Isolates KS2, PG1 and R2 are biosurfactant producers and PG5, R1 are non-producers. Fourteen different consortia were designed involving both biosurfactant producing and non-producing isolates. Consortium 10, which comprises two Bacillus strains namely, Bacillus pumilus KS2 and Bacillus cereus R2 (identified by 16s rRNA sequencing has shown the best result in the desired degradation of crude oil. The consortium showed degradation up to 84.15% of total petroleum hydrocarbon (TPH after five weeks of incubation, as revealed from gravimetric analysis. FTIR (Fourier transform infrared and GCMS (Gas chromatography-mass spectrometer analyses were correlated with gravimetric data which reveals that the consortium has removed a wide range of petroleum hydrocarbons in comparison with abiotic control including different aliphatic and aromatic hydrocarbons.

  4. Development of an Efficient Bacterial Consortium for the Potential Remediation of Hydrocarbons from Contaminated Sites.

    Science.gov (United States)

    Patowary, Kaustuvmani; Patowary, Rupshikha; Kalita, Mohan C; Deka, Suresh

    2016-01-01

    The intrinsic biodegradability of hydrocarbons and the distribution of proficient degrading microorganisms in the environment are very crucial for the implementation of bioremediation practices. Among others, one of the most favorable methods that can enhance the effectiveness of bioremediation of hydrocarbon-contaminated environment is the application of biosurfactant producing microbes. In the present study, the biodegradation capacities of native bacterial consortia toward total petroleum hydrocarbons (TPH) with special emphasis to poly aromatic hydrocarbons were determined. The purpose of the study was to isolate TPH degrading bacterial strains from various petroleum contaminated soil of Assam, India and develop a robust bacterial consortium for bioremediation of crude oil of this native land. From a total of 23 bacterial isolates obtained from three different hydrocarbons contaminated samples five isolates, namely KS2, PG1, PG5, R1, and R2 were selected as efficient crude oil degraders with respect to their growth on crude oil enriched samples. Isolates KS2, PG1, and R2 are biosurfactant producers and PG5, R1 are non-producers. Fourteen different consortia were designed involving both biosurfactant producing and non-producing isolates. Consortium 10, which comprises two Bacillus strains namely, Bacillus pumilus KS2 and B. cereus R2 (identified by 16s rRNA sequencing) has shown the best result in the desired degradation of crude oil. The consortium showed degradation up to 84.15% of TPH after 5 weeks of incubation, as revealed from gravimetric analysis. FTIR (Fourier transform infrared) and GCMS (Gas chromatography-mass spectrometer) analyses were correlated with gravimetric data which reveals that the consortium has removed a wide range of petroleum hydrocarbons in comparison with abiotic control including different aliphatic and aromatic hydrocarbons.

  5. Consortium for Oral Health-Related Informatics: Improving Dental Research, Education, and Treatment

    OpenAIRE

    Stark, Paul C.; Kalenderian, Elsbeth; White, Joel M.; Walji, Muhammad F; Stewart, Denice C. L.; Kimmes, Nicole; Meng, Thomas R.; Willis, George P.; DeVries, Ted; Chapman, Robert J.

    2010-01-01

    Advances in informatics, particularly the implementation of electronic health records (EHR), in dentistry have facilitated the exchange of information. The majority of dental schools in North America use the same EHR system, providing an unprecedented opportunity to integrate these data into a repository that can be used for oral health education and research. In 2007, fourteen dental schools formed the Consortium for Oral Health-Related Informatics (COHRI). Since its inception, COHRI has est...

  6. Overview of the Consortium for the Advanced Simulation of Light Water Reactors (CASL)

    OpenAIRE

    Kulesza Joel A.; Franceschini Fausto; Evans Thomas M.; Gehin Jess C.

    2016-01-01

    The Consortium for Advanced Simulation of Light Water Reactors (CASL) was established in July 2010 for the purpose of providing advanced modeling and simulation solutions for commercial nuclear reactors. The primary goal is to provide coupled, higher-fidelity, usable modeling and simulation capabilities than are currently available. These are needed to address light water reactor (LWR) operational and safety performance-defining phenomena that are not yet able to be fully modeled taking a fir...

  7. Development of an Efficient Bacterial Consortium for the Potential Remediation of Hydrocarbons from Contaminated Sites

    Science.gov (United States)

    Patowary, Kaustuvmani; Patowary, Rupshikha; Kalita, Mohan C.; Deka, Suresh

    2016-01-01

    The intrinsic biodegradability of hydrocarbons and the distribution of proficient degrading microorganisms in the environment are very crucial for the implementation of bioremediation practices. Among others, one of the most favorable methods that can enhance the effectiveness of bioremediation of hydrocarbon-contaminated environment is the application of biosurfactant producing microbes. In the present study, the biodegradation capacities of native bacterial consortia toward total petroleum hydrocarbons (TPH) with special emphasis to poly aromatic hydrocarbons were determined. The purpose of the study was to isolate TPH degrading bacterial strains from various petroleum contaminated soil of Assam, India and develop a robust bacterial consortium for bioremediation of crude oil of this native land. From a total of 23 bacterial isolates obtained from three different hydrocarbons contaminated samples five isolates, namely KS2, PG1, PG5, R1, and R2 were selected as efficient crude oil degraders with respect to their growth on crude oil enriched samples. Isolates KS2, PG1, and R2 are biosurfactant producers and PG5, R1 are non-producers. Fourteen different consortia were designed involving both biosurfactant producing and non-producing isolates. Consortium 10, which comprises two Bacillus strains namely, Bacillus pumilus KS2 and B. cereus R2 (identified by 16s rRNA sequencing) has shown the best result in the desired degradation of crude oil. The consortium showed degradation up to 84.15% of TPH after 5 weeks of incubation, as revealed from gravimetric analysis. FTIR (Fourier transform infrared) and GCMS (Gas chromatography-mass spectrometer) analyses were correlated with gravimetric data which reveals that the consortium has removed a wide range of petroleum hydrocarbons in comparison with abiotic control including different aliphatic and aromatic hydrocarbons. PMID:27471499

  8. Genomic analysis reveals key aspects of prokaryotic symbiosis in the phototrophic consortium "Chlorochromatium aggregatum"

    DEFF Research Database (Denmark)

    Liu, Zhenfeng; Müller, Johannes; Li, Tao;

    2013-01-01

    'Chlorochromatium aggregatum' is a phototrophic consortium, a symbiosis that may represent the highest degree of mutual interdependence between two unrelated bacteria not associated with a eukaryotic host. 'Chlorochromatium aggregatum' is a motile, barrel-shaped aggregate formed from a single cell...... of "Candidatus Symbiobacter mobilis," a polarly flagellated, non-pigmented, heterotrophic bacterium, which is surrounded by approximately 15 epibiont cells of Chlorobium chlorochromatii, a non-motile photolithoautotrophic green sulfur bacterium....

  9. Conversion of crude oil to methane by a microbial consortium enriched from oil reservoir production waters

    OpenAIRE

    Berdugo-Clavijo, Carolina; Lisa M. Gieg

    2014-01-01

    The methanogenic biodegradation of crude oil is an important process occurring in petroleum reservoirs and other oil-containing environments such as contaminated aquifers. In this process, syntrophic bacteria degrade hydrocarbon substrates to products such as acetate, and/or H2 and CO2 that are then used by methanogens to produce methane in a thermodynamically dependent manner. We enriched a methanogenic crude oil-degrading consortium from production waters sampled from a low temperature heav...

  10. Rhizoremediation of Petrol Engine Oil Using Biosurfactants Producing Microbial Consortium in Mustard Crop

    OpenAIRE

    Govind Kumar; Rajesh Kumar; Anita Sharma

    2015-01-01

    Contamination of soil / water resources by petroleum products poses severe threats to underground water and soil quality. In the present study biosurfactant producing bacterial cultures were used to degrade petrol engine oil under in situ conditions in the plant rhizosphere system. Two bacterial isolates used in this study were recovered from Haldia oil refinery sites and identified as Pseudomonas aeruginosa (JX100389) and P. moraviensis (JX149542). Application of consortium C2, (Pseudomonas ...

  11. Macronutrients leaf contents of corn in consortium with forage of the genus Panicum and Urochloa

    OpenAIRE

    Verena Micheletti Protes; Marcelo Andreotti; Cássia Maria de Paula Garcia; Marcelo Carvalho Minhoto Teixeira Filho; Keny Samejima Mascarenha Lopes; Ciniro Costa; Erikelly Aline Ribeiro de Santana

    2013-01-01

    In recent years, the corn crop in Brazil has undergone major technological changes, aiming at a sustainable production. This improvement may be related to appropriate management, which includes, among other practices, crop rotation and tillage; that one can get through crop-livestock integration (CLI). The CLI can be done by the consortium sequence or crop rotation with annual forages in order to recover degraded pastures. This work aimed to evaluate the macronutrient leaf content of corn int...

  12. Emerging transporters of clinical importance: an update from the International Transporter Consortium

    OpenAIRE

    Hillgren, K M; Keppler, D.; Zur, A A; Giacomini, K M; Stieger, B; Cass, C E; Zhang, L.

    2013-01-01

    The International Transporter Consortium (ITC) has recently described seven transporters of particular relevance to drug development. Based on the second ITC transporter workshop in 2012, we have identified additional transporters of emerging importance in pharmacokinetics, interference of drugs with transport of endogenous compounds, and drug-drug interactions (DDIs) in humans. The multidrug and toxin extrusion proteins (MATEs, gene symbol SLC47A) mediate excretion of organic cations into bi...

  13. Enrichment and characterization of an anaerobic cellulolytic microbial consortium SQD-1.1 from mangrove soil.

    Science.gov (United States)

    Gao, Zhao-Ming; Xu, Xun; Ruan, Ling-Wei

    2014-01-01

    Enrichment of microbial consortia provides an approach to simulate and investigate microbial communities in natural environments. In this study, a cellulolytic microbial consortium SQD-1.1 was enriched from mangrove soil of Qinglan port (Hainan, China) by 27 times continuous subcultivation under anaerobic static conditions. The consortium could completely degrade 0.2% (w/v) filter paper within 3 days and utilized it as the sole carbon source. PCR-denaturing gradient gel electrophoresis analysis revealed a stable microbial community structure in the incubation process of 10 days and in the procedure of subcultivation. Twenty-four operational taxonomic units belonging to seven phyla were obtained from the full-length 16S rRNA gene library. Five clones, closest related to the genera Alkaliflexus, Clostridium, Alistipes, Spirochaeta, and Trichococcus, were the predominant ones. Among them, M117, phylogeneticly showing high similarity (16S rRNA gene identity, 95.3%) with the cellulolytic anaerobic bacterium Clostridium straminisolvens CSK1(T), was the potential key cellulolytic bacterium. Using the plate cultivation method, 12 strains, including one potential new species and four potential new species of new genera, were isolated. The strain P2, corresponding to the most frequently detected clone (M05) in the 16S rRNA gene library, showed both CMCase and xylanase activity and may be another important cellulolytic bacterium. The findings of cellulase activity in cell pellet and cohesion and dockerin domains in metagenome data further suggested the potential of utilization of cellulosomes by the consortium to degrade cellulose. Consortium SQD-1.1 provides a candidate for investigating the mechanism of cellulose degradation under anoxic conditions in natural environments. PMID:23529681

  14. Effect of Probiotic Consortium on the Local Inflammatory Process in Chronic Periodontitis

    OpenAIRE

    Zhanagul Khasenbekova; Saule Saduakhasova; Alexandr Gulayev; Almagul Kushugulova; Samat Kozhakhmetov; Gulnara Shakhabayeva; Indira Tynybayeva; Talgat Nurgozhin; Zhaxybay Zhumadilov

    2014-01-01

    Introduction: Inflammatory periodontal disease is one of the major concerns of researchers and clinicians, because it can lead to tooth loss and an increased risk of systemic pathologies, even at the age of 35. The purpose of this study was to determine the effects of gelatin-based probiotic consortium on the local and general factors of inflammation in rats with chronic periodontitis. Methods: The study object was a complex of probiotic bacteria based in an odourless 6% gelatin plate with ne...

  15. Response surface methodology for optimization of medium for decolorization of textile dye Direct Black 22 by a novel bacterial consortium.

    Science.gov (United States)

    Mohana, Sarayu; Shrivastava, Shalini; Divecha, Jyoti; Madamwar, Datta

    2008-02-01

    Decolorization and degradation of polyazo dye Direct Black 22 was carried out by distillery spent wash degrading mixed bacterial consortium, DMC. Response surface methodology (RSM) involving a central composite design (CCD) in four factors was successfully employed for the study and optimization of decolorization process. The hyper activities and interactions between glucose concentration, yeast extract concentration, dye concentration and inoculum size on dye decolorization were investigated and modeled. Under optimized conditions the bacterial consortium was able to decolorize the dye almost completely (>91%) within 12h. Bacterial consortium was able to decolorize 10 different azo dyes. The optimum combination of the four variables predicted through RSM was confirmed through confirmatory experiments and hence this bacterial consortium holds potential for the treatment of industrial waste water. Dye degradation products obtained during the course of decolorization were analyzed by HPTLC.

  16. 2012 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Hoh River Watershed, Washington (Delivery 1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Watershed Sciences, Inc. (WSI) collected Light Detection and Ranging (LiDAR) data on the Hoh River watershed survey area for the Puget Sound LiDAR Consortium and...

  17. 2012 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Quinault River Watershed, Washington (Delivery 1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Watershed Sciences, Inc. (WSI) collected Light Detection and Ranging (LiDAR) data on the Quinault watershed survey area for the Puget Sound LiDAR Consortium. This...

  18. 2014 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Cedar River Watershed (Delivery 1)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In September 2013, WSI, a Quantum Spatial company (QSI), was contracted by the Puget Sound LiDAR Consortium (PSLC) to collect Light Detection and Ranging (LiDAR)...

  19. 2014 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Cedar River Watershed (Delivery 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — In September 2013, WSI, a Quantum Spatial company (QSI), was contracted by the Puget Sound LiDAR Consortium (PSLC) to collect Light Detection and Ranging (LiDAR)...

  20. [Investigation of the properties of the soil microbial consortium as a test objects for estimation of integral toxicity].

    Science.gov (United States)

    Dudchik, N V

    2012-01-01

    The properties of a consortium of microorganisms InMI/CH7 selected from of industrial effluent samples have been investigated. The ability of strains to form biofilms was shown to be correlated with their sensitivity to toxicants. PMID:23243731

  1. The Historically Black Colleges and Universities/Minority Institutions Environmental Technology and Waste Management Consortium annual report, 1990--1991

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-12-31

    The HBCU/MI Environmental Technology and Waste Management Consortium was established in January 1990, through a Memorandum of Understanding (MOU) among the member institutions. This group of research-oriented Historically Black Colleges and Universities and Minority Institutions (HBCU/MI) agreed to work together to initiate research, technology development and education programs to address the nation`s critical environmental problems. As a group the HBCU/MI Consortium is uniquely positioned to reach women and the minority populations of African Americans, Hispanics and American Indians. As part of their initial work, they developed the Research, Education, and Technology Transfer (RETT) Plan to actualize the Consortium`s guiding principles. In addition to developing a comprehensive research agenda, four major programs were begun to meet these goals. This report summarizes the 1990--1991 progress.

  2. 2002 Puget Sound LiDAR Consortium (PSLC) Unclassified Topographic LiDAR: Puget Sound Lowlands Washington

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TerraPoint surveyed and created this data for the Puget Sound LiDAR Consortium under contract. The area surveyed is approximately 730 square miles and covers the...

  3. The Cardiac Safety Research Consortium enters its second decade: An invitation to participate.

    Science.gov (United States)

    Turner, J Rick; Kowey, Peter R; Rodriguez, Ignacio; Cabell, Christopher H; Gintant, Gary; Green, Cynthia L; Kunz, Barbara Lopez; Mortara, Justin; Sager, Philip T; Stockbridge, Norman; Wright, Theressa J; Finkle, John; Krucoff, Mitchell W

    2016-07-01

    The Cardiac Safety Research Consortium (CSRC), a transparent, public-private partnership established in 2005 as a Critical Path Program and formalized in 2006 under a Memorandum of Understanding between the United States Food and Drug Administration and Duke University, is entering its second decade. Our continuing goal is to advance paradigms for more efficient regulatory science related to the cardiovascular safety of new therapeutics, both in the United States and globally, particularly where such safety questions add burden to innovative research and development. Operationally, CSRC brings together a broad base of stakeholders from academia, industry, and government agencies in a collaborative forum focused on identifying barriers and then creating novel solutions through shared data, expertise, and collaborative research. This white paper provides a brief overview of the Consortium's activities in its first decade and a context for some of our current activities and future directions. The growth and success of the CSRC have been primarily driven by members' active participation and the development of goodwill and trust throughout our membership, which have facilitated novel collaborations across traditionally competitive or contentious stakeholder boundaries. The continued expansion of our base of participating academicians, industry experts, and regulators will define the Consortium's success in our second decade. It is our hope that sharing our endeavors to date will stimulate additional participation in the CSRC and also provide a model for other groups starting to develop similar collaborative forums. PMID:27297854

  4. Comparative metagenomic analysis of PAH degradation in soil by a mixed microbial consortium.

    Science.gov (United States)

    Zafra, German; Taylor, Todd D; Absalón, Angel E; Cortés-Espinosa, Diana V

    2016-11-15

    In this study, we used a taxonomic and functional metagenomic approach to analyze some of the effects (e.g. displacement, permanence, disappearance) produced between native microbiota and a previously constructed Polycyclic Aromatic Hydrocarbon (PAH)-degrading microbial consortium during the bioremediation process of a soil polluted with PAHs. Bioaugmentation with a fungal-bacterial consortium and biostimulation of native microbiota using corn stover as texturizer produced appreciable changes in the microbial diversity of polluted soils, shifting native microbial communities in favor of degrading specific populations. Functional metagenomics showed changes in gene abundance suggesting a bias towards aromatic hydrocarbon and intermediary degradation pathways, which greatly favored PAH mineralization. In contrast, pathways favoring the formation of toxic intermediates such as cytochrome P450-mediated reactions were found to be significantly reduced in bioaugmented soils. PAH biodegradation in soil using the microbial consortium was faster and reached higher degradation values (84% after 30 d) as a result of an increased co-metabolic degradation when compared with other mixed microbial consortia. The main differences between inoculated and non-inoculated soils were observed in aromatic ring-hydroxylating dioxygenases, laccase, protocatechuate, salicylate and benzoate-degrading enzyme genes. Based on our results, we propose that several concurrent metabolic pathways are taking place in soils during PAH degradation. PMID:27484946

  5. A survey on the attitudes of doctors towards health insurance payment in the medical consortium

    Institute of Scientific and Technical Information of China (English)

    SHI Ge; WU Tao; XU Wei-guo

    2011-01-01

    Background Medical consortium is a specific vertical integration model of regional medical resources.To improve medical resources utilization and control the health insurance costs by fee-for-service plans (FFS),capitation fee and diagnosis-related groups (DRGs),it is important to explore the attitudes of doctors towards the different health insurance payment in the medical consortium in Shanghai.Methods A questionnaire survey was carried out randomly on 50 doctors respectively in 3 different levels medical institutes.Results The statistical results showed that 90% of doctors in tertiary hospitals had the tendency towards FFS,whereas 78% in secondary hospitals towards DRGs and 84% in community health centers towards capitation fee.Conclusions There are some obvious differences on doctors' attitudes towards health insurance payment in 3 different levels hospitals.Thus,it is feasible that health insurance payment should be supposed to the doctors' attitudes using the bundled payments along with the third-party payment as a supervisor within consortium.

  6. Consortium for oral health-related informatics: improving dental research, education, and treatment.

    Science.gov (United States)

    Stark, Paul C; Kalenderian, Elsbeth; White, Joel M; Walji, Muhammad F; Stewart, Denice C L; Kimmes, Nicole; Meng, Thomas R; Willis, George P; DeVries, Ted; Chapman, Robert J

    2010-10-01

    Advances in informatics, particularly the implementation of electronic health records (EHR), in dentistry have facilitated the exchange of information. The majority of dental schools in North America use the same EHR system, providing an unprecedented opportunity to integrate these data into a repository that can be used for oral health education and research. In 2007, fourteen dental schools formed the Consortium for Oral Health-Related Informatics (COHRI). Since its inception, COHRI has established structural and operational processes, governance and bylaws, and a number of work groups organized in two divisions: one focused on research (data standardization, integration, and analysis), and one focused on education (performance evaluations, virtual standardized patients, and objective structured clinical examinations). To date, COHRI (which now includes twenty dental schools) has been successful in developing a data repository, pilot-testing data integration, and sharing EHR enhancements among the group. This consortium has collaborated on standardizing medical and dental histories, developing diagnostic terminology, and promoting the utilization of informatics in dental education. The consortium is in the process of assembling the largest oral health database ever created. This will be an invaluable resource for research and provide a foundation for evidence-based dentistry for years to come. PMID:20930236

  7. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.

    Science.gov (United States)

    Thompson, Paul M; Stein, Jason L; Medland, Sarah E; Hibar, Derrek P; Vasquez, Alejandro Arias; Renteria, Miguel E; Toro, Roberto; Jahanshad, Neda; Schumann, Gunter; Franke, Barbara; Wright, Margaret J; Martin, Nicholas G; Agartz, Ingrid; Alda, Martin; Alhusaini, Saud; Almasy, Laura; Almeida, Jorge; Alpert, Kathryn; Andreasen, Nancy C; Andreassen, Ole A; Apostolova, Liana G; Appel, Katja; Armstrong, Nicola J; Aribisala, Benjamin; Bastin, Mark E; Bauer, Michael; Bearden, Carrie E; Bergmann, Orjan; Binder, Elisabeth B; Blangero, John; Bockholt, Henry J; Bøen, Erlend; Bois, Catherine; Boomsma, Dorret I; Booth, Tom; Bowman, Ian J; Bralten, Janita; Brouwer, Rachel M; Brunner, Han G; Brohawn, David G; Buckner, Randy L; Buitelaar, Jan; Bulayeva, Kazima; Bustillo, Juan R; Calhoun, Vince D; Cannon, Dara M; Cantor, Rita M; Carless, Melanie A; Caseras, Xavier; Cavalleri, Gianpiero L; Chakravarty, M Mallar; Chang, Kiki D; Ching, Christopher R K; Christoforou, Andrea; Cichon, Sven; Clark, Vincent P; Conrod, Patricia; Coppola, Giovanni; Crespo-Facorro, Benedicto; Curran, Joanne E; Czisch, Michael; Deary, Ian J; de Geus, Eco J C; den Braber, Anouk; Delvecchio, Giuseppe; Depondt, Chantal; de Haan, Lieuwe; de Zubicaray, Greig I; Dima, Danai; Dimitrova, Rali; Djurovic, Srdjan; Dong, Hongwei; Donohoe, Gary; Duggirala, Ravindranath; Dyer, Thomas D; Ehrlich, Stefan; Ekman, Carl Johan; Elvsåshagen, Torbjørn; Emsell, Louise; Erk, Susanne; Espeseth, Thomas; Fagerness, Jesen; Fears, Scott; Fedko, Iryna; Fernández, Guillén; Fisher, Simon E; Foroud, Tatiana; Fox, Peter T; Francks, Clyde; Frangou, Sophia; Frey, Eva Maria; Frodl, Thomas; Frouin, Vincent; Garavan, Hugh; Giddaluru, Sudheer; Glahn, David C; Godlewska, Beata; Goldstein, Rita Z; Gollub, Randy L; Grabe, Hans J; Grimm, Oliver; Gruber, Oliver; Guadalupe, Tulio; Gur, Raquel E; Gur, Ruben C; Göring, Harald H H; Hagenaars, Saskia; Hajek, Tomas; Hall, Geoffrey B; Hall, Jeremy; Hardy, John; Hartman, Catharina A; Hass, Johanna; Hatton, Sean N; Haukvik, Unn K; Hegenscheid, Katrin; Heinz, Andreas; Hickie, Ian B; Ho, Beng-Choon; Hoehn, David; Hoekstra, Pieter J; Hollinshead, Marisa; Holmes, Avram J; Homuth, Georg; Hoogman, Martine; Hong, L Elliot; Hosten, Norbert; Hottenga, Jouke-Jan; Hulshoff Pol, Hilleke E; Hwang, Kristy S; Jack, Clifford R; Jenkinson, Mark; Johnston, Caroline; Jönsson, Erik G; Kahn, René S; Kasperaviciute, Dalia; Kelly, Sinead; Kim, Sungeun; Kochunov, Peter; Koenders, Laura; Krämer, Bernd; Kwok, John B J; Lagopoulos, Jim; Laje, Gonzalo; Landen, Mikael; Landman, Bennett A; Lauriello, John; Lawrie, Stephen M; Lee, Phil H; Le Hellard, Stephanie; Lemaître, Herve; Leonardo, Cassandra D; Li, Chiang-Shan; Liberg, Benny; Liewald, David C; Liu, Xinmin; Lopez, Lorna M; Loth, Eva; Lourdusamy, Anbarasu; Luciano, Michelle; Macciardi, Fabio; Machielsen, Marise W J; Macqueen, Glenda M; Malt, Ulrik F; Mandl, René; Manoach, Dara S; Martinot, Jean-Luc; Matarin, Mar; Mather, Karen A; Mattheisen, Manuel; Mattingsdal, Morten; Meyer-Lindenberg, Andreas; McDonald, Colm; McIntosh, Andrew M; McMahon, Francis J; McMahon, Katie L; Meisenzahl, Eva; Melle, Ingrid; Milaneschi, Yuri; Mohnke, Sebastian; Montgomery, Grant W; Morris, Derek W; Moses, Eric K; Mueller, Bryon A; Muñoz Maniega, Susana; Mühleisen, Thomas W; Müller-Myhsok, Bertram; Mwangi, Benson; Nauck, Matthias; Nho, Kwangsik; Nichols, Thomas E; Nilsson, Lars-Göran; Nugent, Allison C; Nyberg, Lars; Olvera, Rene L; Oosterlaan, Jaap; Ophoff, Roel A; Pandolfo, Massimo; Papalampropoulou-Tsiridou, Melina; Papmeyer, Martina; Paus, Tomas; Pausova, Zdenka; Pearlson, Godfrey D; Penninx, Brenda W; Peterson, Charles P; Pfennig, Andrea; Phillips, Mary; Pike, G Bruce; Poline, Jean-Baptiste; Potkin, Steven G; Pütz, Benno; Ramasamy, Adaikalavan; Rasmussen, Jerod; Rietschel, Marcella; Rijpkema, Mark; Risacher, Shannon L; Roffman, Joshua L; Roiz-Santiañez, Roberto; Romanczuk-Seiferth, Nina; Rose, Emma J; Royle, Natalie A; Rujescu, Dan; Ryten, Mina; Sachdev, Perminder S; Salami, Alireza; Satterthwaite, Theodore D; Savitz, Jonathan; Saykin, Andrew J; Scanlon, Cathy; Schmaal, Lianne; Schnack, Hugo G; Schork, Andrew J; Schulz, S Charles; Schür, Remmelt; Seidman, Larry; Shen, Li; Shoemaker, Jody M; Simmons, Andrew; Sisodiya, Sanjay M; Smith, Colin; Smoller, Jordan W; Soares, Jair C; Sponheim, Scott R; Sprooten, Emma; Starr, John M; Steen, Vidar M; Strakowski, Stephen; Strike, Lachlan; Sussmann, Jessika; Sämann, Philipp G; Teumer, Alexander; Toga, Arthur W; Tordesillas-Gutierrez, Diana; Trabzuni, Daniah; Trost, Sarah; Turner, Jessica; Van den Heuvel, Martijn; van der Wee, Nic J; van Eijk, Kristel; van Erp, Theo G M; van Haren, Neeltje E M; van 't Ent, Dennis; van Tol, Marie-Jose; Valdés Hernández, Maria C; Veltman, Dick J; Versace, Amelia; Völzke, Henry; Walker, Robert; Walter, Henrik; Wang, Lei; Wardlaw, Joanna M; Weale, Michael E; Weiner, Michael W; Wen, Wei; Westlye, Lars T; Whalley, Heather C; Whelan, Christopher D; White, Tonya; Winkler, Anderson M; Wittfeld, Katharina; Woldehawariat, Girma; Wolf, Christiane; Zilles, David; Zwiers, Marcel P; Thalamuthu, Anbupalam; Schofield, Peter R; Freimer, Nelson B; Lawrence, Natalia S; Drevets, Wayne

    2014-06-01

    The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way. PMID:24399358

  8. Inner-City Energy and Environmental Education Consortium: Inventory of existing programs. Appendix 13.5

    Energy Technology Data Exchange (ETDEWEB)

    1992-08-21

    This is the ``first effort`` to prepare an inventory of existing educational programs, focused primarily on inner-city youth, in operation in Washington, DC, Baltimore, and Philadelphia. The purpose of the inventory is to identify existing programs which could be augmented, adapted, or otherwise strengthened to help fulfil the mission of the Department of Energy-sponsored Inner-City Energy and Environmental Education Consortium, the mission of which is to recruit and retain inner-city youth to pursue careers in energy-related scientific and technical areas and in environmental restoration and waste management. The Consortium does not want to ``reinvent the wheel`` and all of its members need to learn what others are doing. Each of the 30 participating academic institutions was invited to submit as many program descriptions as they wished. Due to the summer holidays, or because they did not believe than they were carrying out programs relevant to the mission of the Consortium, some institutions did not submit any program descriptions. In addition, several industries, governmental agencies, and not-for-profit institutions were invited to submit program descriptions.

  9. High-efficient nitrogen removal by coupling enriched autotrophic-nitrification and aerobic-denitrification consortiums at cold temperature.

    Science.gov (United States)

    Zou, Shiqiang; Yao, Shuo; Ni, Jinren

    2014-06-01

    This study paid particular attention to total nitrogen removal at low temperature (10°C) by excellent coupling of enriched autotrophic nitrifying and heterotrophic denitrifying consortiums at sole aerobic condition. The maximum specific nitrifying rate of the nitrifying consortium reached 8.85mgN/(gSSh). Further test in four identical lab-scale sequencing batch reactors demonstrated its excellent performance for bioaugmentation in potential applications. On the other hand, the aerobic denitrifying consortium could achieve a specific denitrifying rate of 32.93mgN/(gSSh) under dissolved oxygen of 1.0-1.5mg/L at 10°C. Coupling both kinds of consortiums was proved very successful for a perfect total nitrogen (TN) removal at COD/N of 4 and dissolved oxygen of 1.5-4.5mg/L, which was hardly reached by any single consortium reported previously. The encouraging results from coupling aerobic consortiums implied a huge potential in practical treatment of low-strength domestic wastewater (200-300mg/L COD) during wintertime.

  10. Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2.

    Directory of Open Access Journals (Sweden)

    Tomas Kirchhoff

    Full Text Available Recently, a locus on chromosome 6q22.33 (rs2180341 was reported to be associated with increased breast cancer risk in the Ashkenazi Jewish (AJ population, and this association was also observed in populations of non-AJ European ancestry. In the present study, we performed a large replication analysis of rs2180341 using data from 31,428 invasive breast cancer cases and 34,700 controls collected from 25 studies in the Breast Cancer Association Consortium (BCAC. In addition, we evaluated whether rs2180341 modifies breast cancer risk in 3,361 BRCA1 and 2,020 BRCA2 carriers from 11 centers in the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA. Based on the BCAC data from women of European ancestry, we found evidence for a weak association with breast cancer risk for rs2180341 (per-allele odds ratio (OR = 1.03, 95% CI 1.00-1.06, p = 0.023. There was evidence for heterogeneity in the ORs among studies (I(2 = 49.3%; p = <0.004. In CIMBA, we observed an inverse association with the minor allele of rs2180341 and breast cancer risk in BRCA1 mutation carriers (per-allele OR = 0.89, 95%CI 0.80-1.00, p = 0.048, indicating a potential protective effect of this allele. These data suggest that that 6q22.33 confers a weak effect on breast cancer risk.

  11. Simultaneous cell growth and ethanol production from cellulose by an engineered yeast consortium displaying a functional mini-cellulosome

    Directory of Open Access Journals (Sweden)

    Madan Bhawna

    2011-11-01

    Full Text Available Abstract Background The recalcitrant nature of cellulosic materials and the high cost of enzymes required for efficient hydrolysis are the major impeding steps to their practical usage for ethanol production. Ideally, a recombinant microorganism, possessing the capability to utilize cellulose for simultaneous growth and ethanol production, is of great interest. We have reported recently the use of a yeast consortium for the functional presentation of a mini-cellulosome structure onto the yeast surface by exploiting the specific interaction of different cohesin-dockerin pairs. In this study, we engineered a yeast consortium capable of displaying a functional mini-cellulosome for the simultaneous growth and ethanol production on phosphoric acid swollen cellulose (PASC. Results A yeast consortium composed of four different populations was engineered to display a functional mini-cellulosome containing an endoglucanase, an exoglucanase and a β-glucosidase. The resulting consortium was demonstrated to utilize PASC for growth and ethanol production. The final ethanol production of 1.25 g/L corresponded to 87% of the theoretical value and was 3-fold higher than a similar yeast consortium secreting only the three cellulases. Quantitative PCR was used to enumerate the dynamics of each individual yeast population for the two consortia. Results indicated that the slight difference in cell growth cannot explain the 3-fold increase in PASC hydrolysis and ethanol production. Instead, the substantial increase in ethanol production is consistent with the reported synergistic effect on cellulose hydrolysis using the displayed mini-cellulosome. Conclusions This report represents a significant step towards the goal of cellulosic ethanol production. This engineered yeast consortium displaying a functional mini-cellulosome demonstrated not only the ability to grow on the released sugars from PASC but also a 3-fold higher ethanol production than a similar yeast

  12. Microbial Consortium with High Cellulolytic Activity (MCHCA) for Enhanced Biogas Production.

    Science.gov (United States)

    Poszytek, Krzysztof; Ciezkowska, Martyna; Sklodowska, Aleksandra; Drewniak, Lukasz

    2016-01-01

    The use of lignocellulosic biomass as a substrate in agricultural biogas plants is very popular and yields good results. However, the efficiency of anaerobic digestion, and thus biogas production, is not always satisfactory due to the slow or incomplete degradation (hydrolysis) of plant matter. To enhance the solubilization of the lignocellulosic biomass various physical, chemical and biological pretreatment methods are used. The aim of this study was to select and characterize cellulose-degrading bacteria, and to construct a microbial consortium, dedicated for degradation of maize silage and enhancing biogas production from this substrate. Over 100 strains of cellulose-degrading bacteria were isolated from: sewage sludge, hydrolyzer from an agricultural biogas plant, cattle slurry and manure. After physiological characterization of the isolates, 16 strains (representatives of Bacillus, Providencia, and Ochrobactrum genera) were chosen for the construction of a Microbial Consortium with High Cellulolytic Activity, called MCHCA. The selected strains had a high endoglucanase activity (exceeding 0.21 IU/mL CMCase activity) and a wide range of tolerance to various physical and chemical conditions. Lab-scale simulation of biogas production using the selected strains for degradation of maize silage was carried out in a two-bioreactor system, similar to those used in agricultural biogas plants. The obtained results showed that the constructed MCHCA consortium is capable of efficient hydrolysis of maize silage, and increases biogas production by even 38%, depending on the inoculum used for methane fermentation. The results in this work indicate that the mesophilic MCHCA has a great potential for application on industrial scale in agricultural biogas plants.

  13. Contribution of hot spring bacterial consortium in cadmium and lead bioremediation through quadratic programming model

    International Nuclear Information System (INIS)

    Highlights: • Adsorption of cadmium and lead using hot spring microbial consortium. • Development of empirical models for % adsorption using ANOVA and response surface methodology. • Fitting of the kinetics of adsorption to Freundlich and Langmuir model. • Optimization of the operating parameters to maximize the % of adsorption. -- Abstract: In the present investigation, a number of experiments have been conducted to isolate microbial strains from Taptapani Hot Spring Odisha, India for bioremediation of cadmium and lead. The strains Stenotrophomonas maltophilia (SS1), Aeromonas veronii (SS2) and Bacillus barbaricus (SS3) have shown better adaptation to metal tolerance test, with different concentrations of cadmium and lead and hence have been selected for further studies of metal microbial interaction and optimization. The results of bioremediation process indicate that consortium of thermophilic isolates adsorbed heavy metals more effectively than the individually treated isolates. Therefore, A 24 full factorial central composite design has been employed to analyze the effect of metal ion concentration, microbial concentration and time on removal of heavy metals with consortium. Analysis of variance (ANOVA) shows a high coefficient of determination value. The kinetic data have been fitted to pseudo-first order and second-order models. The isotherm equilibrium data have been well fitted by the Langmuir and Freundlich models. The optimum removal conditions determined for initial ion concentration was 0.3 g/l; contact time 72 h; microbial concentration, 3 ml/l; and pH 7. At optimum adsorption conditions, the adsorption of cadmium and lead are found to be 92% and 93%, respectively, and presence of metals was confirmed through EDS analysis

  14. Contribution of hot spring bacterial consortium in cadmium and lead bioremediation through quadratic programming model

    Energy Technology Data Exchange (ETDEWEB)

    Sen, Sudip Kumar; Raut, Sangeeta; Dora, Tapas Kumar [Department of Biotechnology, Gandhi Institute of Engineering and Technology, Gunupur, Rayagada 765 022, Odisha (India); Mohapatra, Pradeep Kumar Das, E-mail: pkdmvu@gmail.com [Department of Microbiology, Vidyasagar University, Midnapore 721 102, West Bengal (India)

    2014-01-30

    Highlights: • Adsorption of cadmium and lead using hot spring microbial consortium. • Development of empirical models for % adsorption using ANOVA and response surface methodology. • Fitting of the kinetics of adsorption to Freundlich and Langmuir model. • Optimization of the operating parameters to maximize the % of adsorption. -- Abstract: In the present investigation, a number of experiments have been conducted to isolate microbial strains from Taptapani Hot Spring Odisha, India for bioremediation of cadmium and lead. The strains Stenotrophomonas maltophilia (SS1), Aeromonas veronii (SS2) and Bacillus barbaricus (SS3) have shown better adaptation to metal tolerance test, with different concentrations of cadmium and lead and hence have been selected for further studies of metal microbial interaction and optimization. The results of bioremediation process indicate that consortium of thermophilic isolates adsorbed heavy metals more effectively than the individually treated isolates. Therefore, A 24 full factorial central composite design has been employed to analyze the effect of metal ion concentration, microbial concentration and time on removal of heavy metals with consortium. Analysis of variance (ANOVA) shows a high coefficient of determination value. The kinetic data have been fitted to pseudo-first order and second-order models. The isotherm equilibrium data have been well fitted by the Langmuir and Freundlich models. The optimum removal conditions determined for initial ion concentration was 0.3 g/l; contact time 72 h; microbial concentration, 3 ml/l; and pH 7. At optimum adsorption conditions, the adsorption of cadmium and lead are found to be 92% and 93%, respectively, and presence of metals was confirmed through EDS analysis.

  15. Microbial Consortium with High Cellulolytic Activity (MCHCA) for Enhanced Biogas Production.

    Science.gov (United States)

    Poszytek, Krzysztof; Ciezkowska, Martyna; Sklodowska, Aleksandra; Drewniak, Lukasz

    2016-01-01

    The use of lignocellulosic biomass as a substrate in agricultural biogas plants is very popular and yields good results. However, the efficiency of anaerobic digestion, and thus biogas production, is not always satisfactory due to the slow or incomplete degradation (hydrolysis) of plant matter. To enhance the solubilization of the lignocellulosic biomass various physical, chemical and biological pretreatment methods are used. The aim of this study was to select and characterize cellulose-degrading bacteria, and to construct a microbial consortium, dedicated for degradation of maize silage and enhancing biogas production from this substrate. Over 100 strains of cellulose-degrading bacteria were isolated from: sewage sludge, hydrolyzer from an agricultural biogas plant, cattle slurry and manure. After physiological characterization of the isolates, 16 strains (representatives of Bacillus, Providencia, and Ochrobactrum genera) were chosen for the construction of a Microbial Consortium with High Cellulolytic Activity, called MCHCA. The selected strains had a high endoglucanase activity (exceeding 0.21 IU/mL CMCase activity) and a wide range of tolerance to various physical and chemical conditions. Lab-scale simulation of biogas production using the selected strains for degradation of maize silage was carried out in a two-bioreactor system, similar to those used in agricultural biogas plants. The obtained results showed that the constructed MCHCA consortium is capable of efficient hydrolysis of maize silage, and increases biogas production by even 38%, depending on the inoculum used for methane fermentation. The results in this work indicate that the mesophilic MCHCA has a great potential for application on industrial scale in agricultural biogas plants. PMID:27014244

  16. Biodegradation of p-cresol and sulfide removal by a marine-denitrifying consortium.

    Science.gov (United States)

    Meza-Escalante, Edna R; Alvarez, Luis H; Serrano, Denisse; Mendoza, Erika; Bonola, Ramsés

    2015-02-01

    The simultaneous removal of sulfide and p-cresol was carried out by using a marine-denitrifying consortium collected in the coastal zone of Sonora, Mexico. Different experimental conditions were used to evaluate the capacity of the consortium to simultaneously eliminate nitrate, sulfide, and p-cresol. For instance, the first set of assays was conducted at different sulfide concentrations (20, 50, and 100 mg S(2À) L(À1) ), with a fixed concentration of p-cresol (45 mg C L(À1) ). The second set of assays was developed at different concentrations of p-cresol (45, 75, and 100 mg C L(-1) ), in the presence of 20 mg S(2À) L(À1) . In all cases, the concentration of nitrate was stoichiometrically added for the complete oxidization of the substrates. The results showed removal efficiencies up to 92% for p-cresol and nitrate at 20 and 50 mg S(2À) L(À1) ; whereas at 100 mg S(2À) L(À1) removal efficiencies were 77% and 59% for p-cresol and nitrate, respectively. On the other hand, sulfide (20 mg L(À1) ) was completely removed under different concentrations of p-cresol tested, with a partial accumulation of nitrite according to the increment of p-cresol concentration. The results obtained indicate that the marine consortium was able to simultaneously remove the pollutants studied. PMID:25418931

  17. Bioremoval of Am-241 and Cs-137 from liquid radioactive wasters by bacterial consortiums; Biorremocao de Am-241 e Cs-137 de rejeitos radioativos liquidos por consorcios bacterianos

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Rafael Vicente de Padua; Lima, Josenilson B. de; Gomes, Mirella C.; Borba, Tania R.; Bellini, Maria Helena; Marumo, Julio Takehiro; Sakata, Solange Kazumi, E-mail: rpadua@ipen.b, E-mail: sksakata@ipen.b, E-mail: jblima@ipen.b, E-mail: mbmarumo@ipen.b, E-mail: jtmarumo@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-10-26

    This paper evaluates the capacity of two bacterial consortiums of impacted areas in removing the Am-241 and Cs-137 from liquid radioactive wastes.The experiments indicated that the two study consortiums were able to remove 100% of the Cs-137 and Am-241 presents in the waste from 4 days of contact. These results suggest that the bio removal with the selected consortiums, can be a viable technique for the treatment of radioactive wastes containing Am-241 and Cs-137

  18. Enhancing the Decolorizing and Degradation Ability of Bacterial Consortium Isolated from Textile Effluent Affected Area and Its Application on Seed Germination

    OpenAIRE

    2015-01-01

    A bacterial consortium BMP1/SDSC/01 consisting of six isolates was isolated from textile effected soil, sludge, and textile effluent from Hudiara drain near Nishat Mills Limited, Ferozepur Road, Lahore, Pakistan. It was selected because of being capable of degrading and detoxifying red, green, black, and yellow textile dyes. The pH and supplements were optimized to enhance the decolorization ability of the selected consortium. The results indicated that decolorizing ability of consortium for ...

  19. Promotores As Advocates for Community Improvement: Experiences of the Western States REACH Su Comunidad Consortium.

    Science.gov (United States)

    Kutcher, Rachel; Moore-Monroy, Martha; Bello, Elizur; Doyle, Seth; Ibarra, Jorge; Kunz, Susan; Munoz, Rocio; Patton-Lopez, Megan; Sharkey, Joseph R; Wilger, Susan; Alfero, Charlie

    2015-01-01

    The REACH Su Comunidad Consortium worked with 10 communities to address disparities in access to healthy food and physical activity opportunities among Hispanic populations through policy, systems, and environmental (PSE) strategies. Community health workers took leadership roles in the implementation of PSE strategies in partnership with local multisector coalitions. This article describes the role of community health workers in PSE change, the technical and professional development support provided to the REACH Su Comunidad Communities, and highlights professional development needs of community health workers engaging in PSE strategies.

  20. Feasibility of bio-hydrogen production from sewage sludge using defined microbial consortium

    Energy Technology Data Exchange (ETDEWEB)

    Shireen Meher Kotay; Debabrata Das [Fermentation Technology Lab., Department of Biotechnology, Indian Institute of Technology Kharagpur, W.B., INDIA-721302 (India)

    2006-07-01

    Biological hydrogen production potential of a defined microbial consortium consisting of three facultative anaerobes, Enterobacter cloacae IIT-BT 08, Citrobacter freundii IIT-BT L139 and Bacillus coagulans IIT-BT S1 was studied. In this investigation their individual and combinatorial H{sub 2} production capabilities have been studied on defined media and pretreated sewage sludge. Defined medium, MYG (1% w/v Malt extract, 0.4% w/v yeast extract and 1% w/v glucose) with glucose as limiting substrate has been found to be most suitable for hydrogen production. Individually E. cloacae clearly gave higher yield (276 ml H{sub 2}/ g COD reduced) using defined medium than the other two strains. There was no considerable difference in maximal yield of hydrogen from individual and combinatorial (1:1:1 consortium) modes suggesting that E. cloacae dominated in the consortia on defined medium. Contradictorily, B. coagulans gave better bio-hydrogen yield (37.16 ml H{sub 2}/ g COD consumed) than the other two strains when activated sewage sludge was used as substrate. The pretreatment of sludge included sterilization, (15% v/v) dilution and supplementation with 0.5% w/v glucose which was found to be essential to screen out the hydrogen consuming bacteria and ameliorate the hydrogenation. Considering (1:1:1) consortium as inoculum, interestingly yield of hydrogen was recorded to increase to 41.23 ml H{sub 2}/ g COD reduced inferring that in consortium, the substrate utilization was significantly higher. The hydrogen yield from pretreated sludge obtained in this study (35.54 ml H{sub 2}/ g sludge) has been found to be distinctively higher than the earlier reports (8.1 - 16.9 ml H{sub 2} / g sludge). However it was lower compared to the yield obtained from co-digestion of (83:17) food waste and sewage sludge (122 ml H{sub 2}/ g carbohydrate COD). Employing formulated microbial consortia for bio-hydrogen production from sewage sludge was an attempt to augment the hydrogen yield from

  1. Feasibility of bio-hydrogen production from sewage sludge using defined microbial consortium

    Energy Technology Data Exchange (ETDEWEB)

    Shireen Meher Kotay; Debabrata Das [Fermentation Technology Lab., Department of Biotechnology, Indian Institute of Technology Kharagpur, W.B., INDIA-721302 (India)

    2006-07-01

    Biological hydrogen production potential of a defined microbial consortium consisting of three facultative anaerobes, Enterobacter cloacae IIT-BT 08, Citrobacter freundii IIT-BT L139 and Bacillus coagulans IIT-BT S1 was studied. In this investigation their individual and combinatorial H{sub 2} production capabilities have been studied on defined media and pretreated sewage sludge. Defined medium, MYG (1% w/v Malt extract, 0.4% w/v yeast extract and 1% w/v glucose) with glucose as limiting substrate has been found to be most suitable for hydrogen production. Individually E. cloacae clearly gave higher yield (276 ml H{sub 2}/ g COD reduced) using defined medium than the other two strains. There was no considerable difference in maximal yield of hydrogen from individual and combinatorial (1:1:1 consortium) modes suggesting that E. cloacae dominated in the consortia on defined medium. Contradictorily, B. coagulans gave better bio-hydrogen yield (37.16 ml H{sub 2}/g COD consumed) than the other two strains when activated sewage sludge was used as substrate. The pretreatment of sludge included sterilization, (15% v/v) dilution and supplementation with 0.5%w/v glucose which was found to be essential to screen out the hydrogen consuming bacteria and ameliorate the hydrogenation. Considering (1:1:1) consortium as inoculum, interestingly yield of hydrogen was recorded to increase to 41.23 ml H{sub 2}/ g COD reduced inferring that in consortium, the substrate utilization was significantly higher. The hydrogen yield from pretreated sludge obtained in this study (35.54 ml H{sub 2} g sludge) has been found to be distinctively higher than the earlier reports (8.1 - 16.9 ml H{sub 2}/g sludge). However it was lower compared to the yield obtained from co-digestion of (83:17) food waste and sewage sludge (122 ml H{sub 2}/g carbohydrate COD). Employing formulated microbial consortia for bio-hydrogen production from sewage sludge was an attempt to augment the hydrogen yield from sludge

  2. The Diamond university research consortium: nuclear waste characterisation, immobilisation and storage - 16374

    International Nuclear Information System (INIS)

    Legacy waste treatment, storage and disposal, as well as decommissioning and site remediation, from the UK's civil nuclear programme are estimated at a cost of Pounds 70 B. Within the UK, the Nuclear Decommissioning Authority (NDA) directs the strategy for all civil nuclear decommissioning and demanding timescales have been set for remediation of all nuclear sites. Additionally, the Committee on Radioactive Waste Management (CoRWM) recently delivered a recommendation, accepted by Government, that geological disposal in a mined repository presents the 'best available approach' for long term management of the waste legacy. There is therefore a requirement to decommission all power generation and experimental reactors, and fuel reprocessing plants, to decontaminate land, and to return nuclear licensed sites to brown or green field status. The engineering and scientific challenges that lie ahead in meeting these targets are significant, and many of the ideas required to deliver the final end state have not yet been researched. In recognition of this the UK Research Council's Energy Programme released a call for research proposals in the area of nuclear waste management and decommissioning valued at Pounds 4 M. A grant was subsequently awarded in 2008 to a consortium led by the University of Leeds, with member universities from Manchester, Imperial College, Sheffield, Loughborough and University College London. The DIAMOND (Decommissioning, Immobilisation And Management Of Nuclear Wastes For Disposal) consortium will undertake research aligned with the strategic priorities of the NDA and the CoRWM recommendations. Its primary purpose is to be adventurous and to deliver innovation. However, research is also being performed that will be of more immediate benefit to industrial stakeholders, with near-term impact achieved through the adoption of off-the-shelf technology currently implemented by other industries. Currently more than 20 industrial organisations are linked

  3. Global health education consortium: 20 years of leadership in global health and global health education.

    Science.gov (United States)

    Velji, Anvar

    2011-06-01

    The Global Health Education Consortium (GHEC) is a group of universities and institutions committed to improving the health and human rights of underserved populations worldwide through improved education and training of the global health workforce. In the early 1990s, GHEC brought together many of the global health programs in North America to improve competencies and curricula in global health as well as to involve member institutions in health policy, development issues, and delivery of care in the inner cities, marginalized areas, and abroad.

  4. 03-DPACS: an open source solution for critical PACS systems integratedin the 03 Consortium project.

    OpenAIRE

    Beltrame, Marco

    2008-01-01

    ABSTRACT The student started his work towards the PhD. in 2005, joining the Bioengineering and ICT group of the University of Trieste, whose core research was in the e-health area. The personal research project conducted by the PhD student was inserted in the O3 Consortium research project, which had the aim to propose a complete solution for the adoption of open technology in the healthcare environment. The solution should become a whole new model for e-health application and include n...

  5. Cellulosic ethanol production using a yeast consortium displaying a minicellulosome and β-glucosidase

    Directory of Open Access Journals (Sweden)

    Kim Sujin

    2013-02-01

    Full Text Available Abstract Background Cellulosic biomass is considered as a promising alternative to fossil fuels, but its recalcitrant nature and high cost of cellulase are the major obstacles to utilize this material. Consolidated bioprocessing (CBP, combining cellulase production, saccharification, and fermentation into one step, has been proposed as the most efficient way to reduce the production cost of cellulosic bioethanol. In this study, we developed a cellulolytic yeast consortium for CBP, based on the surface display of cellulosome structure, mimicking the cellulolytic bacterium, Clostridium thermocellum. Results We designed a cellulolytic yeast consortium composed of four different yeast strains capable of either displaying a scaffoldin (mini CipA containing three cohesin domains derived from C. thermocellum, or secreting one of the three types of cellulases, C. thermocellum CelA (endoglucanase containing its own dockerin, Trichoderma reesei CBHII (exoglucanase fused with an exogenous dockerin from C. thermocellum, or Aspergillus aculeatus BGLI (β-glucosidase. The secreted dockerin-containing enzymes, CelA and CBHI, were randomly assembled to the surface-displayed mini CipA via cohesin-dockerin interactions. On the other hand, BGLI was independently assembled to the cell surface since we newly found that it already has a cell adhesion characteristic. We optimized the cellulosome activity and ethanol production by controlling the combination ratio among the four yeast strains. A mixture of cells with the optimized mini CipA:CelA:CBHII:BGLI ratio of 2:3:3:0.53 produced 1.80 g/l ethanol after 94 h, indicating about 20% increase compared with a consortium composed of an equal amount of each cell type (1.48 g/l. Conclusions We produced cellulosic ethanol using a cellulolytic yeast consortium, which is composed of cells displaying mini cellulosomes generated via random assembly of CelA and CBHII to a mini CipA, and cells displaying BGLI independently. One

  6. Characterization of a Bioflocculant Produced by a Consortium of Halomonas sp. Okoh and Micrococcus sp. Leo

    OpenAIRE

    Okoh, Anthony I; Mabinya, Leonard V.; Kunle Okaiyeto; Nwodo, Uchechukwu U

    2013-01-01

    The physicochemical and flocculating properties of a bioflocculant produced by a bacterial consortium composed of Halomonas sp. Okoh and Micrococcus sp. Leo were investigated. The purified bioflocculant was cation and pH dependent, and optimally flocculated kaolin clay suspension at a dosage of 0.1 mg/mL. The flocculating activity of the bioflocculant was stimulated in the presence of Ca2+, Mn2+, Al3+ and had a wide pH range of 2–10, with the highest flocculating activity of 86% at pH 8. The ...

  7. Feasibility of bio-hydrogen production from sewage sludge using defined microbial consortium

    International Nuclear Information System (INIS)

    Biological hydrogen production potential of a defined microbial consortium consisting of three facultative anaerobes, Enterobacter cloacae IIT-BT 08, Citrobacter freundii IIT-BT L139 and Bacillus coagulans IIT-BT S1 was studied. In this investigation their individual and combinatorial H2 production capabilities have been studied on defined media and pretreated sewage sludge. Defined medium, MYG (1% w/v Malt extract, 0.4% w/v yeast extract and 1% w/v glucose) with glucose as limiting substrate has been found to be most suitable for hydrogen production. Individually E. cloacae clearly gave higher yield (276 ml H2/ g COD reduced) using defined medium than the other two strains. There was no considerable difference in maximal yield of hydrogen from individual and combinatorial (1:1:1 consortium) modes suggesting that E. cloacae dominated in the consortia on defined medium. Contradictorily, B. coagulans gave better bio-hydrogen yield (37.16 ml H2/g COD consumed) than the other two strains when activated sewage sludge was used as substrate. The pretreatment of sludge included sterilization, (15% v/v) dilution and supplementation with 0.5%w/v glucose which was found to be essential to screen out the hydrogen consuming bacteria and ameliorate the hydrogenation. Considering (1:1:1) consortium as inoculum, interestingly yield of hydrogen was recorded to increase to 41.23 ml H2/ g COD reduced inferring that in consortium, the substrate utilization was significantly higher. The hydrogen yield from pretreated sludge obtained in this study (35.54 ml H2 g sludge) has been found to be distinctively higher than the earlier reports (8.1 - 16.9 ml H2/g sludge). However it was lower compared to the yield obtained from co-digestion of (83:17) food waste and sewage sludge (122 ml H2/g carbohydrate COD). Employing formulated microbial consortia for bio-hydrogen production from sewage sludge was an attempt to augment the hydrogen yield from sludge. (authors)

  8. Connecting Genomic Alterations to Cancer Biology with Proteomics: The NCI Clinical Proteomic Tumor Analysis Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Ellis, Matthew; Gillette, Michael; Carr, Steven A.; Paulovich, Amanda G.; Smith, Richard D.; Rodland, Karin D.; Townsend, Reid; Kinsinger, Christopher; Mesri, Mehdi; Rodriguez, Henry; Liebler, Daniel

    2013-10-03

    The National Cancer Institute (NCI) Clinical Proteomic Tumor Analysis Consortium is applying the latest generation of proteomic technologies to genomically annotated tumors from The Cancer Genome Atlas (TCGA) program, a joint initiative of the NCI and the National Human Genome Research Institute. By providing a fully integrated accounting of DNA, RNA, and protein abnormalities in individual tumors, these datasets will illuminate the complex relationship between genomic abnormalities and cancer phenotypes, thus producing biologic insights as well as a wave of novel candidate biomarkers and therapeutic targets amenable to verifi cation using targeted mass spectrometry methods.

  9. The Solar Energy Consortium of New York Photovoltaic Research and Development Center

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Petra M.

    2012-10-15

    Project Objective: To lead New York State to increase its usage of solar electric systems. The expected outcome is that appropriate technologies will be made available which in turn will help to eliminate barriers to solar energy usage in New York State. Background: The Solar Energy Consortium has been created to lead New York State research on solar systems specifically directed at doubling the efficiency, halving the cost and reducing the cost of installation as well as developing unique form factors for the New York City urban environment.

  10. Innovations and Enhancements for a Consortium of Big-10 University Research and Training Reactors. Final Report

    International Nuclear Information System (INIS)

    The Consortium of Big-10 University Research and Training Reactors was by design a strategic partnership of seven leading institutions. We received the support of both our industry and DOE laboratory partners. Investments in reactor, laboratory and program infrastructure, allowed us to lead the national effort to expand and improve the education of engineers in nuclear science and engineering, to provide outreach and education to pre-college educators and students and to become a key resource of ideas and trained personnel for our U.S. industrial and DOE laboratory collaborators.

  11. Efficiency of inhibitor for biocorrosion influenced by consortium sulfate reducing bacteria on carbon steel

    Science.gov (United States)

    Mahat, Nur Akma; Othman, Norinsan Kamil; Sahrani, Fathul Karim

    2015-09-01

    The inhibition efficiency of benzalkonium chloride (BKC) in controlling biocorrosion on the carbon steel surfaces has been investigated. The carbon steel coupons were incubated in the presence of consortium SRB (C-SRB) with and without BKC for the difference medium concentration. The corrosion rate and inhibition efficiency have been evaluated by a weight loss method. The morphology of biofilm C-SRB on the steel surfaces were characterized with variable pressure scanning electron microscopy (VPSEM). The results revealed that BKC exhibits a low corrosion rate, minimizing the cell growth and biofilm development on the carbon steel surfaces.

  12. Efficiency of inhibitor for biocorrosion influenced by consortium sulfate reducing bacteria on carbon steel

    Energy Technology Data Exchange (ETDEWEB)

    Mahat, Nur Akma; Othman, Norinsan Kamil [School of Applied Physics, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia); Sahrani, Fathul Karim [School of Environment and Natural Resources Science, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor (Malaysia)

    2015-09-25

    The inhibition efficiency of benzalkonium chloride (BKC) in controlling biocorrosion on the carbon steel surfaces has been investigated. The carbon steel coupons were incubated in the presence of consortium SRB (C-SRB) with and without BKC for the difference medium concentration. The corrosion rate and inhibition efficiency have been evaluated by a weight loss method. The morphology of biofilm C-SRB on the steel surfaces were characterized with variable pressure scanning electron microscopy (VPSEM). The results revealed that BKC exhibits a low corrosion rate, minimizing the cell growth and biofilm development on the carbon steel surfaces.

  13. TTA school-based research consortium initiative, the evaluation, final report

    OpenAIRE

    Kushner, S.; Simons, H.; James, D; Jones, K; Yee, W C

    2001-01-01

    This is the final report of the evaluation of th School-Based Research Consortium Initiative which ran in England from 1998 to 2001. The initiative was sponsored via a public/private partnership between the Teacher Training Agency (TTA), a UK Government agency, and the Centre for British Teachers (CfBT), a private not-for-profit company. The aim of the initiative was to create local infrastructures of support and action for teachers to engage ‘in and with’ research. Those infrastructures wer...

  14. The pilot European Alzheimer's Disease Neuroimaging Initiative of the European Alzheimer's Disease Consortium

    DEFF Research Database (Denmark)

    Frisoni, G.B.; Henneman, W.J.; Weiner, M.W.;

    2008-01-01

    BACKGROUND: In North America, the Alzheimer's Disease Neuroimaging Initiative (ADNI) has established a platform to track the brain changes of Alzheimer's disease. A pilot study has been carried out in Europe to test the feasibility of the adoption of the ADNI platform (pilot E-ADNI). METHODS: Seven...... academic sites of the European Alzheimer's Disease Consortium (EADC) enrolled 19 patients with mild cognitive impairment (MCI), 22 with AD, and 18 older healthy persons by using the ADNI clinical and neuropsychological battery. ADNI compliant magnetic resonance imaging (MRI) scans, cerebrospinal fluid...

  15. Effect of Probiotic Consortium on the Local Inflammatory Process in Chronic Periodontitis

    Directory of Open Access Journals (Sweden)

    Zhanagul Khasenbekova

    2014-01-01

    Full Text Available Introduction: Inflammatory periodontal disease is one of the major concerns of researchers and clinicians, because it can lead to tooth loss and an increased risk of systemic pathologies, even at the age of 35. The purpose of this study was to determine the effects of gelatin-based probiotic consortium on the local and general factors of inflammation in rats with chronic periodontitis. Methods: The study object was a complex of probiotic bacteria based in an odourless 6% gelatin plate with neutral flavour. A cellular biomass of the consortium consists of following lactobacilli: Lactobacillus casei subsp. pseudoplantarum, Lactobacillus caseisubsp.casei, L.fermentum, and L. helveticus. The viable cell number was 2.5 x 109 CFU/ml. The model of chronic periodontitis was reproduced in the white random-bred rats that weighed 160-220g, by keeping them on a low-protein diet. After three months, symptoms associated with medium and severe chronic periodontitis were observed in the rats. Application was carried out on the oral mucosa of rats 1 time per day for 14 days. The stickers lacking consortium of microorganisms were used as the placebo. The "Solcoseril" gel was chosen as a comparator. The hematologic, biochemical, and morphological characteristics were investigated. Results: A complete clearance of periodontal pockets was observed during an objective examination of the experimental group rats on the 14th day of the experiment. Moreover, a gingival mucous turned pink, and there were no cyanosis tissues. The local changes were accompanied by improvement in hematological parameters, such as a reduction of blood eosinophilia and neutrophilia, and a recovery of the white blood cells number to the normal degree within the group that received the probiotic complex. A decrease of the acute plethora of microvasculature was observed morphologically as a result of the treatment. There were signs of basal layer activation of the stratified squamous epithelium

  16. The Historically Black Colleges and Universities/Minority Institutions Environmental Technology Consortium annual report 1994--1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-07-01

    The HBCU/MI ET Consortium was established in January 1990, through a Memorandum of Understanding (MOU) among its member institutions. This group of research oriented Historically Black Colleges and Universities and Minority Institutions (HBCU/MIs) agreed to work together to initiate or revise education programs, develop research partnerships with public and private sector organizations, and promote technology development to address the nation`s critical environmental contamination problems. The Consortium`s Research, Education and Technology Transfer (RETT) Plan became the working agenda. The Consortium is a resource for collaboration among the member institutions and with federal an state agencies, national and federal laboratories, industries, (including small businesses), majority universities, and two and four-year technical colleges. As a group of 17 institutions geographically located in the southern US, the Consortium is well positioned to reach a diverse group of women and minority populations of African Americans, Hispanics and American Indians. This Report provides a status update on activities and achievements in environmental curriculum development, outreach at the K--12 level, undergraduate and graduate education, research and development, and technology transfer.

  17. Naphthalene degradation by bacterial consortium (DV-AL) developed from Alang-Sosiya ship breaking yard, Gujarat, India.

    Science.gov (United States)

    Patel, Vilas; Jain, Siddharth; Madamwar, Datta

    2012-03-01

    Naphthalene degrading bacterial consortium (DV-AL) was developed by enrichment culture technique from sediment collected from the Alang-Sosiya ship breaking yard, Gujarat, India. The 16S rRNA gene based molecular analyzes revealed that the bacterial consortium (DV-AL) consisted of four strains namely, Achromobacter sp. BAB239, Pseudomonas sp. DV-AL2, Enterobacter sp. BAB240 and Pseudomonas sp. BAB241. Consortium DV-AL was able to degrade 1000 ppm of naphthalene in Bushnell Haas medium (BHM) containing peptone (0.1%) as co-substrate with an initial pH of 8.0 at 37°C under shaking conditions (150 rpm) within 24h. Maximum growth rate and naphthalene degradation rate were found to be 0.0389 h(-1) and 80 mg h(-1), respectively. Consortium DV-AL was able to utilize other aromatic and aliphatic hydrocarbons such as benzene, phenol, carbazole, petroleum oil, diesel fuel, and phenanthrene and 2-methyl naphthalene as sole carbon source. Consortium DV-AL was also efficient to degrade naphthalene in the presence of other pollutants such as petroleum hydrocarbons and heavy metals.

  18. ESTABLISHMENT OF AN INDUSTRY-DRIVEN CONSORTIUM FOCUSED ON IMPROVING THE PRODUCTION PERFORMANCE OF DOMESTIC STRIPPER WELLS

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison

    2001-06-28

    The Pennsylvania State University, under contract to the US Department of Energy, National Energy Technology Laboratory will establish, promote, and manage a national industry-driven Stripper Well Consortium (SWC) that will be focused on improving the production performance of domestic petroleum and/or natural gas stripper wells. The consortium creates a partnership with the US petroleum and natural gas industries and trade associations, state funding agencies, academia, and the National Energy Technology Laboratory. This report serves as the first quarterly technical progress report for the SWC. The SWC is in its infancy; however, interest from the petroleum and natural gas industry has grown substantially during this reporting period. As of December 31, 2000, nineteen members have joined the consortium and several other companies have expressed interest. During the last three months, efforts were focused on the development of the necessary infrastructure and membership base to begin the consortium technology development activities. These efforts included: (1) preparing a draft constitution and bylaws, (2) developing draft membership application forms, (3) developing an intellectual property statement, (4) providing overview presentations to trade association meetings, and (5) marketing the consortium individually to potential members. These activities are discussed in further detail in this first quarterly technical progress report.

  19. Effect of VOCs and methane in the biological oxidation of the ferrous ion by an acidophilic consortium.

    Science.gov (United States)

    Almenglo, F; Ramírez, M; Gómez, J M; Cantero, D; Revah, S; González-Sánchez, A

    2012-01-01

    During the elimination of H2S from biogas in an aqueous ferric sulphate solution, volatile organic compounds (VOCs) and methane are absorbed and may have an effect on the subsequent biological regeneration of ferric ion. This study was conducted to investigate the effect of maximum concentrations of methane and some VOCs found in biogas on the ferrous oxidation of an acidophilic microbial consortium (FO consortium). The presence and impact of heterotrophic microorganisms on the activity of the acidophilic consortium was also evaluated. No effect on the ferrous oxidation rate was found with gas concentrations of 1500 mg toluene m(-3), 1400 mg 2-butanol m(-3) or 1250 mg 1,2-dichloroethane m(-3), nor with methane at gas concentrations ranging from 15-25% (v/v). A tenfold increase in VOCs concentrations totally inhibited the microbial activity of the FO consortium and the heterotrophs. The presence of a heterotrophic fungus may promote the autotrophic growth of the FO consortium. PMID:22629626

  20. FORGE Canada Consortium: outcomes of a 2-year national rare-disease gene-discovery project.

    Science.gov (United States)

    Beaulieu, Chandree L; Majewski, Jacek; Schwartzentruber, Jeremy; Samuels, Mark E; Fernandez, Bridget A; Bernier, Francois P; Brudno, Michael; Knoppers, Bartha; Marcadier, Janet; Dyment, David; Adam, Shelin; Bulman, Dennis E; Jones, Steve J M; Avard, Denise; Nguyen, Minh Thu; Rousseau, Francois; Marshall, Christian; Wintle, Richard F; Shen, Yaoqing; Scherer, Stephen W; Friedman, Jan M; Michaud, Jacques L; Boycott, Kym M

    2014-06-01

    Inherited monogenic disease has an enormous impact on the well-being of children and their families. Over half of the children living with one of these conditions are without a molecular diagnosis because of the rarity of the disease, the marked clinical heterogeneity, and the reality that there are thousands of rare diseases for which causative mutations have yet to be identified. It is in this context that in 2010 a Canadian consortium was formed to rapidly identify mutations causing a wide spectrum of pediatric-onset rare diseases by using whole-exome sequencing. The FORGE (Finding of Rare Disease Genes) Canada Consortium brought together clinicians and scientists from 21 genetics centers and three science and technology innovation centers from across Canada. From nation-wide requests for proposals, 264 disorders were selected for study from the 371 submitted; disease-causing variants (including in 67 genes not previously associated with human disease; 41 of these have been genetically or functionally validated, and 26 are currently under study) were identified for 146 disorders over a 2-year period. Here, we present our experience with four strategies employed for gene discovery and discuss FORGE's impact in a number of realms, from clinical diagnostics to the broadening of the phenotypic spectrum of many diseases to the biological insight gained into both disease states and normal human development. Lastly, on the basis of this experience, we discuss the way forward for rare-disease genetic discovery both in Canada and internationally.

  1. A rapid selection strategy for an anodophilic consortium for microbial fuel cells

    KAUST Repository

    Wang, Aijie

    2010-07-01

    A rapid selection method was developed to enrich for a stable and efficient anodophilic consortium (AC) for microbial fuel cells (MFCs). A biofilm sample from a microbial electrolysis cell was serially diluted up to 10-9 in anaerobic phosphate buffer solution and incubated in an Fe(III)-acetate medium, and an Fe(III)-reducing AC was obtained for dilutions up to 10-6. The activity of MFC inoculated with the enrichment AC was compared with those inoculated with original biofilm or activated sludge. The power densities and Coulombic efficiencies of the AC (226 mW/m2, 34%) were higher than those of the original biofilm (209 mW/m2, 23%) and activated sludge (192 mW/m2, 19%). The start-up period of the AC (60 h) was also shorter than those obtained with the other inocula (biofilm, 95 h; activated sludge, 300 h). This indicated that such a strategy is highly efficient for obtaining an anodophilic consortium for improving the performance of an MFC. © 2010 Elsevier Ltd.

  2. International Consortium on Mammographic Density: Methodology and population diversity captured across 22 countries.

    Science.gov (United States)

    McCormack, Valerie A; Burton, Anya; dos-Santos-Silva, Isabel; Hipwell, John H; Dickens, Caroline; Salem, Dorria; Kamal, Rasha; Hartman, Mikael; Lee, Charmaine Pei Ling; Chia, Kee-Seng; Ozmen, Vahit; Aribal, Mustafa Erkin; Flugelman, Anath Arzee; Lajous, Martín; Lopez-Riduara, Ruy; Rice, Megan; Romieu, Isabelle; Ursin, Giske; Qureshi, Samera; Ma, Huiyan; Lee, Eunjung; van Gils, Carla H; Wanders, Johanna O P; Vinayak, Sudhir; Ndumia, Rose; Allen, Steve; Vinnicombe, Sarah; Moss, Sue; Won Lee, Jong; Kim, Jisun; Pereira, Ana; Garmendia, Maria Luisa; Sirous, Reza; Sirous, Mehri; Peplonska, Beata; Bukowska, Agnieszka; Tamimi, Rulla M; Bertrand, Kimberly; Nagata, Chisato; Kwong, Ava; Vachon, Celine; Scott, Christopher; Perez-Gomez, Beatriz; Pollan, Marina; Maskarinec, Gertraud; Giles, Graham; Hopper, John; Stone, Jennifer; Rajaram, Nadia; Teo, Soo-Hwang; Mariapun, Shivaani; Yaffe, Martin J; Schüz, Joachim; Chiarelli, Anna M; Linton, Linda; Boyd, Norman F

    2016-02-01

    Mammographic density (MD) is a quantitative trait, measurable in all women, and is among the strongest markers of breast cancer risk. The population-based epidemiology of MD has revealed genetic, lifestyle and societal/environmental determinants, but studies have largely been conducted in women with similar westernized lifestyles living in countries with high breast cancer incidence rates. To benefit from the heterogeneity in risk factors and their combinations worldwide, we created an International Consortium on Mammographic Density (ICMD) to pool individual-level epidemiological and MD data from general population studies worldwide. ICMD aims to characterize determinants of MD more precisely, and to evaluate whether they are consistent across populations worldwide. We included 11755 women, from 27 studies in 22 countries, on whom individual-level risk factor data were pooled and original mammographic images were re-read for ICMD to obtain standardized comparable MD data. In the present article, we present (i) the rationale for this consortium; (ii) characteristics of the studies and women included; and (iii) study methodology to obtain comparable MD data from original re-read films. We also highlight the risk factor heterogeneity captured by such an effort and, thus, the unique insight the pooled study promises to offer through wider exposure ranges, different confounding structures and enhanced power for sub-group analyses.

  3. Competitive advantage of bacteriocinogenic strains within lactic acid bacteria consortium of raw milk cheese

    Directory of Open Access Journals (Sweden)

    Irena Rogelj

    2011-03-01

    Full Text Available The presence of gene determinants for different bacteriocins has been already demonstrated in traditional Slovenian types of raw milk cheeses ‘Tolminc’ and ‘Kraški’. These genes were present also in the cultivable microbiota. In this research the aim was to establish how the presence of gene determinants for bacteriocins in microbial consortia is reflected in its antimicrobial activity. In addition, one of the goals was to determine whether the strains that carry gene determinants for bacteriocins have any competitive growth advantage in microbial population. Microbial consortium of ‘Tolminc’ cheese was propagated in milk and examined at the end of propagation its antimicrobial activity and the presence of gene determinants for bacteriocins. Comparison of the results obtained before and after propagation leaded to the conclusion that most of the strains possessing gene determinants for bacteriocins were unable to persist during propagation. The strains which did persist during propagation carried gene determinants for enterocins P, L50B and cytolysin. Antimicrobial activity of consortium before and after propagation was not substantially different and cannot be attributed to any of detected bacteriocins.

  4. Deep-biosphere consortium of fungi and prokaryotes in Eocene subseafloor basalts.

    Science.gov (United States)

    Bengtson, S; Ivarsson, M; Astolfo, A; Belivanova, V; Broman, C; Marone, F; Stampanoni, M

    2014-11-01

    The deep biosphere of the subseafloor crust is believed to contain a significant part of Earth's biomass, but because of the difficulties of directly observing the living organisms, its composition and ecology are poorly known. We report here a consortium of fossilized prokaryotic and eukaryotic micro-organisms, occupying cavities in deep-drilled vesicular basalt from the Emperor Seamounts, Pacific Ocean, 67.5 m below seafloor (mbsf). Fungal hyphae provide the framework on which prokaryote-like organisms are suspended like cobwebs and iron-oxidizing bacteria form microstromatolites (Frutexites). The spatial inter-relationships show that the organisms were living at the same time in an integrated fashion, suggesting symbiotic interdependence. The community is contemporaneous with secondary mineralizations of calcite partly filling the cavities. The fungal hyphae frequently extend into the calcite, indicating that they were able to bore into the substrate through mineral dissolution. A symbiotic relationship with chemoautotrophs, as inferred for the observed consortium, may be a pre-requisite for the eukaryotic colonization of crustal rocks. Fossils thus open a window to the extant as well as the ancient deep biosphere.

  5. Microbial consortium influence upon steel corrosion rate, using polarisation resistance and electrochemical noise techniques

    International Nuclear Information System (INIS)

    The microbiologically influenced corrosion (MIC) is a process, which affects the oil industry, particularly the hydrocarbons extraction, transport and storage. MIC evaluation has been normally based upon microbiological tests, and just a few references mention alternating methods, such as the electrochemical techniques, which can be used as criteria for their evaluation. In this work, two different electrochemical laboratory techniques, polarisation resistance and electrochemical noise were used, in order to determine the corrosion behaviour of a microbial consortium, obtained from a gas transporting pipeline, located in the southeast of Mexico. The bacteria population growth was found to be different for sessile and plancktonic microorganisms. Moreover, long incubation times were required to reach the maximum concentration of sessile bacteria. The electrochemical techniques used in this study exhibited a similar tendency on the corrosion rate behaviour with time, and values above 0.3 mm year-1 were observed at the end of the experiments. The experiments were complemented with surface analysis. Scanning electron microscope observation of APIXL52 steel coupons, exposed to the consortium action, revealed bacteria presence, as well as a damaged steel surface. A type of localized corrosion was observed on the metal surface, and it was associated to the bacteria effect

  6. Determining client need in a multi-state fetal alcohol syndrome consortium: from training to practice

    Directory of Open Access Journals (Sweden)

    Haynes George

    2007-02-01

    Full Text Available Abstract Background A multi-state consortium was developed in the US to conduct baseline data collection and intervention research on fetal alcohol syndrome. Each state employed support specialists whose job it was to reduce or eliminate alcohol consumption in women who were at high risk for drinking alcohol during their pregnancy. The purpose of this paper is to report how support specialists in three primarily rural/frontier states were trained to assess client need and how client need was actually assessed in the field. Methods A qualitative process evaluation was conducted using semi-structured interviews. Interviews were conducted with state staff involved in support specialist training and consortium activities and the support specialists themselves. Inductive analyses were conducted with interview data. Results Need determination varied by state and for one state within the state. How support specialists were trained to assess need and how need was assessed in the field was mostly congruent. Conclusion Process evaluation is an effective method for providing practical and useful answers to questions that cannot be answered by outcome evaluation alone.

  7. Creation of the Probiotic Consortium on the Base of Strains of Bifidobacterium spp.

    Directory of Open Access Journals (Sweden)

    Kozhakhmetov, S. S.

    2009-01-01

    Full Text Available Nowadays, a widespread circulation of disbiotic conditions among the population of all ages in Kazakhstan requires an active development in industry for both preparations and products with probiotic properties. The gained bacterial isolates, Bifidobacterium adolescentis 180, B. breve 204, B. breve 584 and B. breve 587 were used in our researches and screening showed they possess high probiotic properties. The consortium possesses strong antimicrobial activity to pathogenic and potentially-pathogenic microflora, insulated during disbacteriosis, as well as from vagina and urea. They are able to produce vitamin B12 and also have antimutagenic activity. As a result, the consortium on the base of strains of Bifidobacterium spp. was received, possessing the following advantages: contains live mass of microbial, antagonistically active strains B. breve and B. adolescentis; contains more than 10^9 alive Bifidobacteria; does not contain plasmids, which means that it could not be a carrier of antibiotic stability for Gram-positive receptive pathogenic and potentially-pathogenic microflora.

  8. The EuroMoon Consortium - Lunar Surface Composition and Processes - Progress Report

    Science.gov (United States)

    Grande, Manuel

    2016-04-01

    Recent years have seen new observations from an international fleet of lunar probes (including, Chang'e 1, 2, and 3, Chandrayaan-1, Kaguya (SELENE), LRO, LADEE, and SMART-1). Many excellent instruments were led and funded from Europe. Large amounts of historic data exist from the Moon, and the main aim of the EuroMoon consortium is to scientifically exploit this data. Our consortium of the leaders of recent European experiments is reinforced with additional leading international Lunar scientists. Our aim is to investigate the Lunar surface composition and processes that take place in the uppermost layers of the Lunar regolith, including the water cycle on the Moon. The detailed understanding of the physics that processes the material at the surface, altering and recycling it, has been greatly facilitated by recent observations. We have recently begun a coordinated program on this topic at ISSI in Bern, and we will report progress, as well as outlining our future intentions for coordinated proposals to the EU in conjunction with EuroPlanet.

  9. The Waste-Management Education and Research Consortium (WERC) annual progress report, 1990--1991

    International Nuclear Information System (INIS)

    In February, 1990, the Secretary of Energy, James Watkins approved a grant for a waste (management) education and research consortium program by New Mexico State University (NMSU) to the US Department of Energy (DOE) . This program known by the acronym, ''WERC'' includes NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology (NMIMT), the Los Alamos National Laboratory and the Sandia National Laboratories. The program is designed to provide an integrated approach to the national need via the following: (1) Education in waste management by the Consortium universities resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. The term waste management is used in a broad sense throughout this paper and includes all aspects of environmental management and environmental restoration. (2) Research programs at the leading edge, providing training to faculty and students and feeding into the education programs. (3) Education and research at the campuses, as well as from three field sites. (4) Ties with other multi-disciplinary university facilities. (5) Ties with two National Laboratories located in New Mexico. (6) Technology transfer and education via an existing fiber optic network, a proposed satellite link, and an existing state-wide extension program. (7) An outreach program to interest others in environmental management, especially precollege students, minority students and practitioners in the field. This report summarizes the accomplishments and status at the end of the first year

  10. Microbial consortium influence upon steel corrosion rate, using polarisation resistance and electrochemical noise techniques

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez Gayosso, M.J.; Zavala Olivares, G.; Ruiz Ordaz, N.; Juarez Ramirez, C.; Garcia Esquivel, R.; Padilla Viveros, A

    2004-10-01

    The microbiologically influenced corrosion (MIC) is a process, which affects the oil industry, particularly the hydrocarbons extraction, transport and storage. MIC evaluation has been normally based upon microbiological tests, and just a few references mention alternating methods, such as the electrochemical techniques, which can be used as criteria for their evaluation. In this work, two different electrochemical laboratory techniques, polarisation resistance and electrochemical noise were used, in order to determine the corrosion behaviour of a microbial consortium, obtained from a gas transporting pipeline, located in the southeast of Mexico. The bacteria population growth was found to be different for sessile and plancktonic microorganisms. Moreover, long incubation times were required to reach the maximum concentration of sessile bacteria. The electrochemical techniques used in this study exhibited a similar tendency on the corrosion rate behaviour with time, and values above 0.3 mm year{sup -1} were observed at the end of the experiments. The experiments were complemented with surface analysis. Scanning electron microscope observation of APIXL52 steel coupons, exposed to the consortium action, revealed bacteria presence, as well as a damaged steel surface. A type of localized corrosion was observed on the metal surface, and it was associated to the bacteria effect.

  11. Plasma interface unit the common heart to the rosetta plasma consortium.

    Science.gov (United States)

    Lee, C.; Balogh, A.; Beek, T.; Carr, C.; Ludlam, M.

    2003-04-01

    The Rosetta Plasma Consortium (RPC) is a 5 sensor experiment which is being carried on board by the Rosetta mission to study the plasma environment of the comet Wirtanen in 2012. At the centre of the five sensors is the Plasma Interface Unit (PIU) which provides the common central processing and power condition for the five instruments as well as the only interface to the spacecraft subsystem. However the PIU have supplied more than hardware to the consortium - it has also been responsible for the organisational centre for the design, integration and testing of the RPC package and in future will be the centre focus for its operations. We describe how the main elements of the PIU fulfill the diverse functional and operational requirements of the sensors on the one hand, and the spacecraft interface on the other hand. Such packages, supporting diverse, multi-sensor scientific instruments are considered necessary for many future space missions. We will conclude with a brief discussion of expected benefits and implications for the development, test and operational aspects of future scientific payloads.

  12. Characterization of a Bioflocculant Produced by a Consortium of Halomonas sp. Okoh and Micrococcus sp. Leo

    Directory of Open Access Journals (Sweden)

    Anthony I. Okoh

    2013-10-01

    Full Text Available The physicochemical and flocculating properties of a bioflocculant produced by a bacterial consortium composed of Halomonas sp. Okoh and Micrococcus sp. Leo were investigated. The purified bioflocculant was cation and pH dependent, and optimally flocculated kaolin clay suspension at a dosage of 0.1 mg/mL. The flocculating activity of the bioflocculant was stimulated in the presence of Ca2+, Mn2+, Al3+ and had a wide pH range of 2–10, with the highest flocculating activity of 86% at pH 8. The bioflocculant was thermostable and retained more than 70% of its flocculating activity after being heated at 80 °C for 30 min. Thermogravimetric analyses revealed a partial thermal decomposition of the biofloculant at 400 °C. The infrared spectrum showed the presence of hydroxyl, carboxyl and amino moieties as functional groups. The bioflocculant produced by the bacterial consortium appears to hold promising alternative to inorganic and synthetic organic flocculants that are widely used in wastewater treatment.

  13. Consortium NCS/GNS: Disposal of spent nuclear fuel from the DKFZ (Heidelberg, Germany)

    Energy Technology Data Exchange (ETDEWEB)

    Vallentin, R. [GNS Gesellschaft fuer Nuklear-Service mbH, Hollestr. 7 A, D- 45127 Essen, WTI Wissenschaftlich- Technische Ingenieurberatung GmbH, K.-H.-Beckurtsstr. 8, 52428 Juelich (Germany); Juenger, B. [DKFZ Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg (Germany); Schmidt, T. [NCS Nuclear Cargo and Service, Rodenbacher Chaussee 6, D-63457 Hanau (Germany)

    2002-07-01

    Before the decommissioning of the TRIGA HD II reactor of the 'Deutsches Krebsforschungszentrum' in Heidelberg (DKFZ) the spent nuclear fuel (126 TRIGA- F/A) had to be discharged from the reactor and shipped in 2001 to the United States. The Consortium NCS/GNS together with the DKFZ carried out this task including the following essential details: Implementation of structural measures inside the reactor building. Development and fabrication of loading units for the FIA. Development and fabrication of a transfer system for the loading units. Obtaining new German and US certifications for the casks. Loading of the casks. Shipment of the casks from DKFZ to the United States by road and sea. The successful completion of this task once again proved the operational experience of the Consortium NCS/GNS which will be useful for further worldwide shipments of spent nuclear fuel from research reactors. e.g. shipments from Europe, South America and Australia to the United States and France. (author)

  14. Appalachian Clean Coal Technology Consortium. Final report, October 10, 1994--March 31, 1997

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, R.H.; Parekh, B.K.; Meloy, T.

    1997-12-31

    The Appalachian Clean Coal Technology Consortium is a group comprised of representatives from the Virginia Polytechnic Institute and State University, West Virginia University, and the University of Kentucky Center for Applied Energy Research, that was formed to pursue research in areas related to the treatment and processing of fine coal. Each member performed research in their respective areas of expertise and the report contained herein encompasses the results that were obtained for the three major tasks that the Consortium undertook from October, 1994 through March, 1997. In the first task, conducted by Virginia Polytechnic Institute, novel methods (both mechanical and chemical) for dewatering fine coal were examined. In the second task, the Center for Applied Energy Research examined novel approaches for destabilization of [highly stable] flotation froths. And in the third task, West Virginia University developed physical and mathematical models for fine coal spirals. The Final Report is written in three distinctive chapters, each reflecting the individual member`s task report. Recommendations for further research in those areas investigated, as well as new lines of pursuit, are suggested.

  15. A Proposal for the use of the Consortium Method in the Design-build system

    Science.gov (United States)

    Miyatake, Ichiro; Kudo, Masataka; Kawamata, Hiroyuki; Fueta, Toshiharu

    In view of the necessity for efficient implementation of public works projects, it is expected to utilize advanced technical skills of private firms, for the purpose of reducing project costs, improving performance and functions of construction objects, and reducing work periods, etc. The design-build system is a method to order design and construction as a single contract, including design of structural forms and main specifications of the construction object. This is a system in which high techniques of private firms can be utilized, as a means to ensure qualities of design and construction, rational design, and efficiency of the project. The objective of this study is to examine the use of a method to form a consortium of civil engineering consultants and construction companies, as it is an issue related to the implementation of the design-build method. Furthermore, by studying various forms of consortiums to be introduced in future, it proposes procedural items required to utilize this method, during the bid and after signing a contract, such as the estimate submission from the civil engineering consultants etc.

  16. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

    Directory of Open Access Journals (Sweden)

    Luca eFreschi

    2015-09-01

    Full Text Available The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are available through the International Pseudomonas Consortium Database (http://ipcd.ibis.ulaval.ca/. Here, we present our strategy and the results that emerged from the analysis of the first 389 genomes. With as yet unmatched resolution, our results confirm that P. aeruginosa strains can be divided into three major groups that are further divided into subgroups, some not previously reported in the literature. We also provide the first snapshot of P. aeruginosa strain diversity with respect to antibiotic resistance. Our approach will allow us to draw potential links between environmental strains and those implicated in human and animal infections, understand how patients become infected and how the infection evolves over time as well as identify prognostic markers for better evidence-based decisions on patient care.

  17. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

    Science.gov (United States)

    Freschi, Luca; Jeukens, Julie; Kukavica-Ibrulj, Irena; Boyle, Brian; Dupont, Marie-Josée; Laroche, Jérôme; Larose, Stéphane; Maaroufi, Halim; Fothergill, Joanne L.; Moore, Matthew; Winsor, Geoffrey L.; Aaron, Shawn D.; Barbeau, Jean; Bell, Scott C.; Burns, Jane L.; Camara, Miguel; Cantin, André; Charette, Steve J.; Dewar, Ken; Déziel, Éric; Grimwood, Keith; Hancock, Robert E. W.; Harrison, Joe J.; Heeb, Stephan; Jelsbak, Lars; Jia, Baofeng; Kenna, Dervla T.; Kidd, Timothy J.; Klockgether, Jens; Lam, Joseph S.; Lamont, Iain L.; Lewenza, Shawn; Loman, Nick; Malouin, François; Manos, Jim; McArthur, Andrew G.; McKeown, Josie; Milot, Julie; Naghra, Hardeep; Nguyen, Dao; Pereira, Sheldon K.; Perron, Gabriel G.; Pirnay, Jean-Paul; Rainey, Paul B.; Rousseau, Simon; Santos, Pedro M.; Stephenson, Anne; Taylor, Véronique; Turton, Jane F.; Waglechner, Nicholas; Williams, Paul; Thrane, Sandra W.; Wright, Gerard D.; Brinkman, Fiona S. L.; Tucker, Nicholas P.; Tümmler, Burkhard; Winstanley, Craig; Levesque, Roger C.

    2015-01-01

    The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are available through the International Pseudomonas Consortium Database (http://ipcd.ibis.ulaval.ca/). Here, we present our strategy and the results that emerged from the analysis of the first 389 genomes. With as yet unmatched resolution, our results confirm that P. aeruginosa strains can be divided into three major groups that are further divided into subgroups, some not previously reported in the literature. We also provide the first snapshot of P. aeruginosa strain diversity with respect to antibiotic resistance. Our approach will allow us to draw potential links between environmental strains and those implicated in human and animal infections, understand how patients become infected and how the infection evolves over time as well as identify prognostic markers for better evidence-based decisions on patient care. PMID:26483767

  18. Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium.

    Science.gov (United States)

    Freschi, Luca; Jeukens, Julie; Kukavica-Ibrulj, Irena; Boyle, Brian; Dupont, Marie-Josée; Laroche, Jérôme; Larose, Stéphane; Maaroufi, Halim; Fothergill, Joanne L; Moore, Matthew; Winsor, Geoffrey L; Aaron, Shawn D; Barbeau, Jean; Bell, Scott C; Burns, Jane L; Camara, Miguel; Cantin, André; Charette, Steve J; Dewar, Ken; Déziel, Éric; Grimwood, Keith; Hancock, Robert E W; Harrison, Joe J; Heeb, Stephan; Jelsbak, Lars; Jia, Baofeng; Kenna, Dervla T; Kidd, Timothy J; Klockgether, Jens; Lam, Joseph S; Lamont, Iain L; Lewenza, Shawn; Loman, Nick; Malouin, François; Manos, Jim; McArthur, Andrew G; McKeown, Josie; Milot, Julie; Naghra, Hardeep; Nguyen, Dao; Pereira, Sheldon K; Perron, Gabriel G; Pirnay, Jean-Paul; Rainey, Paul B; Rousseau, Simon; Santos, Pedro M; Stephenson, Anne; Taylor, Véronique; Turton, Jane F; Waglechner, Nicholas; Williams, Paul; Thrane, Sandra W; Wright, Gerard D; Brinkman, Fiona S L; Tucker, Nicholas P; Tümmler, Burkhard; Winstanley, Craig; Levesque, Roger C

    2015-01-01

    The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are available through the International Pseudomonas Consortium Database (http://ipcd.ibis.ulaval.ca/). Here, we present our strategy and the results that emerged from the analysis of the first 389 genomes. With as yet unmatched resolution, our results confirm that P. aeruginosa strains can be divided into three major groups that are further divided into subgroups, some not previously reported in the literature. We also provide the first snapshot of P. aeruginosa strain diversity with respect to antibiotic resistance. Our approach will allow us to draw potential links between environmental strains and those implicated in human and animal infections, understand how patients become infected and how the infection evolves over time as well as identify prognostic markers for better evidence-based decisions on patient care. PMID:26483767

  19. [Autonomy despite multimorbidity in old age--the Berlin-based AMA research consortium].

    Science.gov (United States)

    Schüz, B; Dräger, D; Richter, S; Kummer, K; Kuhlmey, A; Tesch-Römer, C

    2011-12-01

    The proportion of the population with multiple illnesses increases with age and growing numbers of people are now living to a very old age. Despite medical progress and improved living conditions, many old people have to deal with physical, psychological, and social impairments. It is a crucial challenge for health and social policy to support the elderly with health-related impairments in their desire to lead as independent a life as possible. Against this background the research consortium Autonomy Despite Multimorbidity in Old Age (AMA I) examined the extent to which the self-determined life style of multimorbid old and very old persons can be supported and maintained. In order to reflect the diversity of life worlds of the elderly, the study sample included participants who were not notably impaired in their everyday functioning, participants in need of nursing care and participants with cognitive impairments. Moreover, the sample comprised both older persons who were still living in their own homes and nursing home residents. The studies conducted within the AMA framework focused on the resources available to old persons living in different situations and on how these resources can be strengthened. This article presents findings from the first phase of funding of the AMA research consortium. In a second phase of funding (2011-2013, AMA II), sustainable practice-based interventions are being developed to mobilize resources which can help multimorbid older persons to maintain their autonomy and the practical viability of these interventions will be tested. PMID:22270971

  20. Characterization of microalgae-bacteria consortium cultured in landfill leachate for carbon fixation and lipid production.

    Science.gov (United States)

    Zhao, Xin; Zhou, Yan; Huang, Sheng; Qiu, Duanyang; Schideman, Lance; Chai, Xiaoli; Zhao, Youcai

    2014-03-01

    The characteristics of cultivating high-density microalgae-bacteria consortium with landfill leachate was tested in this study. Landfill leachate was collected from Laogang landfill operated for over 10 years in Shanghai, China. The maximum biomass concentration of 1.58g L(-1) and chlorophyll a level of 22mg L(-1) were obtained in 10% leachate spike ratio. Meanwhile, up to 90% of the total nitrogen in landfill leachate was removed in culture with 10% leachate spike ratio with a total nitrogen concentration of 221.6mg L(-1). The fluorescence peak of humic-like organic matters red shifted to longer wavelengths by the end of culture, indicating that microalgae-bacteria consortium was effective for treating landfill leachate contaminants. Furthermore, with the leachate spike ratio of 10%, the maximum lipid productivity and carbon fixation were 24.1 and 65.8mg L(-1)d(-1), respectively. Results of this research provide valuable information for optimizing microalgae culture in landfill leachate.

  1. The Waste-Management Education and Research Consortium (WERC) annual progress report, 1990--1991

    Energy Technology Data Exchange (ETDEWEB)

    None

    1991-02-25

    In February, 1990, the Secretary of Energy, James Watkins approved a grant for a waste (management) education and research consortium program by New Mexico State University (NMSU) to the US Department of Energy (DOE) . This program known by the acronym, WERC'' includes NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology (NMIMT), the Los Alamos National Laboratory and the Sandia National Laboratories. The program is designed to provide an integrated approach to the national need via the following: (1) Education in waste management by the Consortium universities resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. The term waste management is used in a broad sense throughout this paper and includes all aspects of environmental management and environmental restoration. (2) Research programs at the leading edge, providing training to faculty and students and feeding into the education programs. (3) Education and research at the campuses, as well as from three field sites. (4) Ties with other multi-disciplinary university facilities. (5) Ties with two National Laboratories located in New Mexico. (6) Technology transfer and education via an existing fiber optic network, a proposed satellite link, and an existing state-wide extension program. (7) An outreach program to interest others in environmental management, especially precollege students, minority students and practitioners in the field. This report summarizes the accomplishments and status at the end of the first year.

  2. Chemometric formulation of bacterial consortium-AVS for improved decolorization of resonance-stabilized and heteropolyaromatic dyes.

    Science.gov (United States)

    Kumar, Madhava Anil; Kumar, Vaidyanathan Vinoth; Premkumar, Manickam Periyaraman; Baskaralingam, Palanichamy; Thiruvengadaravi, Kadathur Varathachary; Dhanasekaran, Anuradha; Sivanesan, Subramanian

    2012-11-01

    A bacterial consortium-AVS, consisting of Pseudomonas desmolyticum NCIM 2112, Kocuria rosea MTCC 1532 and Micrococcus glutamicus NCIM 2168 was formulated chemometrically, using the mixture design matrix based on the design of experiments methodology. The formulated consortium-AVS decolorized acid blue 15 and methylene blue with a higher average decolorization rate, which is more rapid than that of the pure cultures. The UV-vis spectrophotometric, Fourier transform infra red spectrophotometric and high performance liquid chromatographic analysis confirm that the decolorization was due to biodegradation by oxido-reductive enzymes, produced by the consortium-AVS. The toxicological assessment of plant growth parameters and the chlorophyll pigment concentrations of Phaseolus mungo and Triticum aestivum seedlings revealed the reduced toxic nature of the biodegraded products.

  3. Teaching About Critical Earth Issues in the 2U Semester Online Consortium (Invited)

    Science.gov (United States)

    Wysession, M. E.

    2013-12-01

    In the spring of 2014 Washington University will present one of the first courses, entitled 'Critical Earth Issues,' in a new experiment in online education to be carried out by a consortium of Universities working with the production company 2U. The consortium, consisting of Washington University in St. Louis, Boston College, Brandeis University, Emory University, Northwestern University, the University of North Carolina at Chapel Hill, and the University of Notre Dame, will all offer courses that can be taken by each other's students. In addition, three affiliate institutions so far (Baylor University, Southern Methodist University, and Temple University) have agree to allow their students to take online courses from this consortium, and transfer credit will be granted from the consortium institution teaching a particular course to students from other institutions as well. A total of eleven courses from the seven consortium schools are being taught in the fall of 2013. 'Critical Earth Issues,' to be taught the next spring, will be the first geoscience course taught. The structure of the course will be very different from traditional MOOCs. Half of the course (80 minutes per week) will be asynchronous and produced in advance by the company 2U. This is designed to take the place of the lecture component of a class, but it can take a variety of forms. While there are traditional lecture segments and filmed demos, these are also broken up by assignments for the students in order to make the 'lecture' segment more interactive. Sometimes the students will have to answer short or long questions before they can go on to the next part of the asynchronous material. Students can only get to the assignment at the end if they work their way through all the produced and interactive segments. This material will often also prompt them to upload an 'assignment,' such as uploading photos of different rocks that are used for the buildings at their host institution (to be shared

  4. Fifteen Years of Collaborative Innovation and Achievement: NASA Nebraska Space Grant Consortium 15-Year Program Performance and Results Report

    Science.gov (United States)

    Schaaf, Michaela M.; Bowen, Brent D.; Fink, Mary M.; Nickerson, Jocelyn S.; Avery, Shelly; Carstenson, Larry; Dugan, James; Farritor, Shane; Joyce, James; Rebrovich, Barb

    2003-01-01

    Condensing five years of significant work into a brief narrative fitting PPR requirements gave the affiliates of the Nebraska Space Grant a valuable chance for reflection. Achievements of Space Grant in Nebraska were judiciously chosen for this document that best illustrate the resultant synergism of this consortium, keeping in mind that these examples are only a representation of greater activity throughout the state. Following are highlights of many of the finer and personal achievements for Nebraska Space Grant. The Consortium welcomes inquiries to elaborate on any of these accomplishments.

  5. 25 CFR 1000.17 - What documents must a Tribe/Consortium submit to OSG to apply for admission to the applicant pool?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What documents must a Tribe/Consortium submit to OSG to apply for admission to the applicant pool? 1000.17 Section 1000.17 Indians OFFICE OF THE ASSISTANT.../Consortium submit to OSG to apply for admission to the applicant pool? In addition to the...

  6. 25 CFR 1000.55 - Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this...

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this subpart? 1000.55 Section 1000.55 Indians OFFICE OF THE ASSISTANT... Negotiation Grants Advance Planning Grant Funding § 1000.55 Can a Tribe/Consortium appeal within DOI...

  7. 25 CFR 1000.68 - May non-BIA bureaus provide technical assistance to a Tribe/Consortium in drafting its planning...

    Science.gov (United States)

    2010-04-01

    ... Process § 1000.68 May non-BIA bureaus provide technical assistance to a Tribe/Consortium in drafting its... technical assistance to the Tribe/Consortium in the drafting of its planning grant application. ... 25 Indians 2 2010-04-01 2010-04-01 false May non-BIA bureaus provide technical assistance to...

  8. 25 CFR 1000.50 - What must a Tribe/Consortium seeking a planning grant submit in order to meet the planning phase...

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false What must a Tribe/Consortium seeking a planning grant submit in order to meet the planning phase requirements? 1000.50 Section 1000.50 Indians OFFICE OF THE... seeking a planning grant submit in order to meet the planning phase requirements? A Tribe/Consortium...

  9. 25 CFR 1000.212 - What is the role of the Tribe/Consortium when a bureau initiates a public meeting?

    Science.gov (United States)

    2010-04-01

    ... AFFAIRS, DEPARTMENT OF THE INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT.../Consortium should meet to plan and discuss the conduct of the meeting, meeting protocols, and general... 25 Indians 2 2010-04-01 2010-04-01 false What is the role of the Tribe/Consortium when a...

  10. Effect of trichloroethylene and tetrachloroethylene on methane oxidation and community structure of methanotrophic consortium.

    Science.gov (United States)

    Choi, Sun-Ah; Lee, Eun-Hee; Cho, Kyung-Suk

    2013-01-01

    The methane oxidation rate and community structure of a methanotrophic consortium were analyzed to determine the effects of trichloroethylene (TCE) and tetrachloroethylene (PCE) on methane oxidation. The maximum methane oxidation rate (Vmax ) of the consortium was 326.8 μmol·g-dry biomass(-1)·h(-1), and it had a half-saturation constant (Km ) of 143.8 μM. The addition of TCE or PCE resulted in decreased methane oxidation rates, which were decreased from 101.73 to 5.47-24.64 μmol·g-dry biomass(-1)·h(-1) with an increase in the TCE-to-methane ratio, and to 61.95-67.43 μmol·g-dry biomass(-1)·h(-1) with an increase in the PCE-to-methane ratio. TCE and PCE were non-competitive inhibitors for methane oxidation, and their inhibition constants (Ki ) were 33.4 and 132.0 μM, respectively. When the methanotrophic community was analyzed based on pmoA using quantitative real-time PCR (qRT-PCR), the pmoA gene copy numbers were shown to decrease from 7.3 ± 0.7 × 10(8) to 2.1-5.0 × 10(7) pmoA gene copy number · g-dry biomass(-1) with an increase in the TCE-to-methane ratio and to 2.5-7.0 × 10(7) pmoA gene copy number · g-dry biomass(-1) with an increase in the PCE-to-methane ratio. Community analysis by microarray demonstrated that Methylocystis (type II methanotrophs) were the most abundant in the methanotrophic community composition in the presence of TCE. These results suggest that toxic effects caused by TCE and PCE change not only methane oxidation rates but also the community structure of the methanotrophic consortium.

  11. Earth Hazards Consortium: a Unique Approach to Student-Centered Learning

    Science.gov (United States)

    Mann, C. P.; Granados, H. D.; Durant, A.; Wolf, R. E.; Girard, G.; Javier, I. H.; Cisneros, M.; Rose, W.; Sánchez, S. S.; Stix, J.

    2006-12-01

    The Earth Hazards (EHaz) consortium consists of six research-based universities in the United States (Michigan Technological University, University at Buffalo), Canada (McGill University, Simon Fraser University) and México (Universidad Nacional Autónoma de México, Universidad de Colima) funded by the U.S. Department of Education, Human Resources and Skills Development Canada, and the Secretaría de Educación Pública of México, as part of the North American Free Trade Agreement. The objective of the consortium is to expose students to a wide variety of scientific and cultural perspectives in the mitigation of geological natural hazards in North America. This four year program is multi-faceted, including student exchanges, graduate level, web-based courses in volcanology, and intensive group field trips. In 2005 to 2006, a total of 27 students were mobilized among the three countries. In this first year, the videoconferencing course focused on caldera supervolcanoes with weekly discussion leaders from various fields of volcanology. At the end of the course the students participated in a field trip to Long Valley and Yellowstone calderas. Also during the first year of the program, México hosted an International Course on Volcanic Hazards Map Construction. The course was attended by graduate students from Mexico and the United States, included lectures from noted guest speakers, and involved a field trip to Popocatepetl volcano. A student survey demonstrated that during the videoconferencing the students benefited by the weekly interaction with well- known volcanologists at the top of their field. Students who participated in the field trip benefited from an outstanding opportunity to link the theoretical concepts covered during the course with the field aspects of supervolcano systems, as well as the opportunity to network amongst their peers. Feedback from students who went abroad indicates that the program provided support for internship opportunities

  12. Earth Hazards Consortium: a Novel Approach to Student Education in Geoscience

    Science.gov (United States)

    Mann, C. P.; Delgado Granados, H.; Escobar Wolf, R.; Durant, A.; Girard, G.; Calder, E.; Dominguez, T.; Roberge, J.; Rose, W.; Stix, J.; Varley, N.; Williams-Jones, G.; Hernandez Javier, I.; Salinas Sanchez, S.

    2007-05-01

    The Earth Hazards (Ehaz) consortium consists of six research-based universities in the United States (Michigan Technological University, University of New York at Buffalo), Canada (McGill University, Simon Fraser University) and Mexico (Universidad Nacional Autónoma de México, Universidad de Colima) funded by the U.S. Department of Education, Human Resources and Skills Development Canada, and the Secretaría de Educación Pública of Mexico, as part of the North American Free Trade Agreement. The objective of the consortium is to expose students to a wide variety of scientific and cultural perspectives in the mitigation of geological natural hazards in North America. This four-year program is multi-faceted, including student exchanges, graduate level, web-based courses in volcanology, and intensive group field trips. In 2005 to 2006, a total of 27 students were mobilized among the three countries. In this first year, the videoconferencing course focused on caldera "Supervolcanoes" with weekly discussion leaders from various fields of volcanology. At the end of the course the students participated in a field trip to Long Valley and Yellowstone calderas. Also during the first year of the program, Mexico hosted an International Course on Volcanic Hazards Map Construction. The course was attended by graduate students from Mexico and the United States, included lectures from noted guest speakers, and involved a field trip to Popocatépetl volcano. The multi-university course focus for 2007 is Volcanic Edifice Failure with a field trip planned in August 2007 to the Cascades and Western Canada. A student survey from 2006 demonstrated that (1) during the videoconferencing the students benefited by the weekly interaction with well-known volcanologists at the top of their field, (2) the field trip provided an outstanding opportunity for participants to link the theoretical concepts covered during the course with the field aspects of supervolcano systems, as well as the

  13. A strategy for providing electronic library services to members of the AGATE Consortium

    Science.gov (United States)

    Thompson, J. Garth

    1995-01-01

    In November, 1992, NASA Administrator Daniel Goldin established a Task Force to evaluate conditions which have lead to the precipitous decline of the US General Aviation System and to recommend actions needed to re-establish US leadership in General Aviation. The Task Force Report and a report by Dr. Bruce J. Holmes, Manager of the General Aviation/Commuter Office at NASA Langley Research Center provided the directions for the formation of the Advanced General Aviation Transport Experiments (AGATE), a consortium of government, industry and university committed to the revitalization of the US General Aviation Industry. One of the recommendations of the Task Force Report was that 'a central repository of information should be created to disseminate NASA research as well as other domestic and foreign aeronautical research that has been accomplished, is ongoing or is planned... A user friendly environment should be created.' This paper describes technical and logistic issues and recommends a plan for providing technical information to members of the AGATE Consortium. It is recommended that the General Aviation office establish and maintain an electronic literature page on the AGATE server. This page should provide a user friendly interface to existing technical report and index servers identified in the report and listed in the Recommendations section. A page should also be provided which gives links to Web resources. A list of specific resources is provided in the Recommendations section. Links should also be provided to a page with tips on searching, a form to provide for feedback and suggestions from users for other resources. Finally, a page should be maintained which provides pointers to other resources like the LaRCsim workstation simulation software which is avail from LaRC at no cost. The developments of the Web is very dynamic. These developments should be monitored regularly by the GA staff and links to additional resources should be provided on the server as

  14. Hydrogen Production by Geobacter Species and a Mixed Consortium in a Microbial Electrolysis Cell

    KAUST Repository

    Call, D. F.

    2009-10-09

    A hydrogen utilizing exoelectrogenic bacterium (Geobacter sulfurreducens) was compared to both a nonhydrogen oxidizer (Geobacter metallireducens) and a mixed consortium in order to compare the hydrogen production rates and hydrogen recoveries of pure and mixed cultures in microbial electrolysis cells (MECs). At an applied voltage of 0.7 V, both G. sulfurreducens and the mixed culture generated similar current densities (ca. 160 A/m3), resulting in hydrogen production rates of ca. 1.9 m3 H2/m 3/day, whereas G. metallireducens exhibited lower current densities and production rates of 110 ± 7 A/m3 and 1.3 ± 0.1 m3 H2/m3/day, respectively. Before methane was detected in the mixed-culture MEC, the mixed consortium achieved the highest overall energy recovery (relative to both electricity and substrate energy inputs) of 82% ± 8% compared to G. sulfurreducens (77% ± 2%) and G. metallireducens (78% ± 5%), due to the higher coulombic efficiency of the mixed consortium. At an applied voltage of 0.4 V, methane production increased in the mixed-culture MEC and, as a result, the hydrogen recovery decreased and the overall energy recovery dropped to 38% ± 16% compared to 80% ± 5% for G. sulfurreducens and 76% ± 0% for G. metallireducens. Internal hydrogen recycling was confirmed since the mixed culture generated a stable current density of 31 ± 0 A/m3 when fed hydrogen gas, whereas G. sulfurreducens exhibited a steady decrease in current production. Community analysis suggested that G. sulfurreducens was predominant in the mixed-culture MEC (72% of clones) despite its relative absence in the mixed-culture inoculum obtained from a microbial fuel cell reactor (2% of clones). These results demonstrate that Geobacter species are capable of obtaining similar hydrogen production rates and energy recoveries as mixed cultures in an MEC and that high coulombic efficiencies in mixed culture MECs can be attributed in part to the recycling of hydrogen into current. Copyright

  15. The VUELCO project consortium: new interdisciplinary research for improved risk mitigation and management during volcanic unrest

    Science.gov (United States)

    Gottsmann, J.

    2012-04-01

    Volcanic unrest is a complex multi-hazard phenomenon of volcanism. The fact that unrest may, but not necessarily must lead to an imminent eruption contributes significant uncertainty to short-term hazard assessment of volcanic activity world-wide. Although it is reasonable to assume that all eruptions are associated with precursory activity of some sort, the knowledge of the causative links between subsurface processes, resulting unrest signals and imminent eruption is, today, inadequate to deal effectively with crises of volcanic unrest. This results predominantly from the uncertainties in identifying the causative processes of unrest and as a consequence in forecasting its short-term evolution. However, key for effective risk mitigation and management during unrest is the early and reliable identification of changes in the subsurface dynamics of a volcano and their assessment as precursors to an impending eruption. The VUELCO project consortium has come together for a multi-disciplinary attack on the origin, nature and significance of volcanic unrest from the scientific contributions generated by collaboration of ten partners in Europe and Latin America. Dissecting the science of monitoring data from unrest periods at six type volcanoes in Italy, Spain, the West Indies, Mexico and Ecuador the consortium will create global strategies for 1) enhanced monitoring capacity and value, 2) mechanistic data interpretation and 3) identification of reliable eruption precursors; all from the geophysical, geochemical and geodetic fingerprints of unrest episodes. Experiments will establish a mechanistic understanding of subsurface processes capable of inducing unrest and aid in identifying key volcano monitoring parameters indicative of the nature of unrest processes. Numerical models will help establish a link between the processes and volcano monitoring data to inform on the causes of unrest and its short-term evolution. Using uncertainty assessment and new short

  16. Macronutrients leaf contents of corn in consortium with forage of the genus Panicum and Urochloa

    Directory of Open Access Journals (Sweden)

    Verena Micheletti Protes

    2013-12-01

    Full Text Available In recent years, the corn crop in Brazil has undergone major technological changes, aiming at a sustainable production. This improvement may be related to appropriate management, which includes, among other practices, crop rotation and tillage; that one can get through crop-livestock integration (CLI. The CLI can be done by the consortium sequence or crop rotation with annual forages in order to recover degraded pastures. This work aimed to evaluate the macronutrient leaf content of corn intercropped with forages of the genus Panicum and Urochloa. The experiment was conducted at the Farm for Teaching, Research and Extension, Faculty of Engineering - UNESP, Ilha Solteira in an Oxisol in Savannah conditions, being in no-tillage for 8 years (previous corn crop. In nitrogen fertilization was applying 100 kg ha-1 of N as urea. The experimental design was a randomized block with four replications and five treatments: Panicum maximum cv. Tanzania sown during the nitrogen fertilization (CTD of the corn; Panicum maximum cv. Mombaça sown during the nitrogen fertilization (CMD of the corn; Urochloa brizantha Xaraes sown during the occasion of nitrogen fertilization (CBD of the corn; Urochloa ruziziensis sown during the nitrogen fertilization (CRD of the corn, and corn without intercropping (CWI. The grasses seeds were mixed with fertilizer minutes before sowing and placed in fertilizer seeder compartment and the fertilizer were deposited in the soil at a depth of 0.03 m in the amount of 5 kg ha-1. It was observed that there was no significant difference between the single corn tillage and the corn in intercropping with different modalities of forages of genus Panicum and Urochloa to foliar contents of N, P, K, Ca and Mg, demonstrating that the consortium did not influence the absorption of nutrients by corn. In respect to S, the consortium CTD, was higher only when compared at CWI, however, did not differ significantly from the others (Table 1. The

  17. Practical Examples and Benefits of Implementing Open Geospatial Consortium Data Formats

    Science.gov (United States)

    Bayer, E.

    2005-12-01

    "Open Systems" have become a re-occuring mantra expressed by all vendors in the GIS industry. One vendor's definition of Open defines system integration at an application tier while another at the data tier. As the Open Geospatial Consortium (OGC) data definitions (WFS and WMS) become more accepted in the market place we are seeing a more data centric approach to integrating Geospatial information. This benefits all in the GIS industry by: Reducing the cost of ownership for software Minimizing data maintenance requirements Eliminating the need to copy and translate data from one system to another Allowing end users to choose the best tool for the job We will review some practical examples of OGC compliant implementations for enterprise GIS data sharing.

  18. Simulating social-ecological systems: the Island Digital Ecosystem Avatars (IDEA) consortium.

    Science.gov (United States)

    Davies, Neil; Field, Dawn; Gavaghan, David; Holbrook, Sally J; Planes, Serge; Troyer, Matthias; Bonsall, Michael; Claudet, Joachim; Roderick, George; Schmitt, Russell J; Zettler, Linda Amaral; Berteaux, Véronique; Bossin, Hervé C; Cabasse, Charlotte; Collin, Antoine; Deck, John; Dell, Tony; Dunne, Jennifer; Gates, Ruth; Harfoot, Mike; Hench, James L; Hopuare, Marania; Kirch, Patrick; Kotoulas, Georgios; Kosenkov, Alex; Kusenko, Alex; Leichter, James J; Lenihan, Hunter; Magoulas, Antonios; Martinez, Neo; Meyer, Chris; Stoll, Benoit; Swalla, Billie; Tartakovsky, Daniel M; Murphy, Hinano Teavai; Turyshev, Slava; Valdvinos, Fernanda; Williams, Rich; Wood, Spencer

    2016-01-01

    Systems biology promises to revolutionize medicine, yet human wellbeing is also inherently linked to healthy societies and environments (sustainability). The IDEA Consortium is a systems ecology open science initiative to conduct the basic scientific research needed to build use-oriented simulations (avatars) of entire social-ecological systems. Islands are the most scientifically tractable places for these studies and we begin with one of the best known: Moorea, French Polynesia. The Moorea IDEA will be a sustainability simulator modeling links and feedbacks between climate, environment, biodiversity, and human activities across a coupled marine-terrestrial landscape. As a model system, the resulting knowledge and tools will improve our ability to predict human and natural change on Moorea and elsewhere at scales relevant to management/conservation actions. PMID:26998258

  19. Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process.

    Science.gov (United States)

    Caudle, Kelly E; Klein, Teri E; Hoffman, James M; Muller, Daniel J; Whirl-Carrillo, Michelle; Gong, Li; McDonagh, Ellen M; Sangkuhl, Katrin; Thorn, Caroline F; Schwab, Matthias; Agundez, Jose A G; Freimuth, Robert R; Huser, Vojtech; Lee, Ming Ta Michael; Iwuchukwu, Otito F; Crews, Kristine R; Scott, Stuart A; Wadelius, Mia; Swen, Jesse J; Tyndale, Rachel F; Stein, C Michael; Roden, Dan; Relling, Mary V; Williams, Marc S; Johnson, Samuel G

    2014-02-01

    The Clinical Pharmacogenetics Implementation Consortium (CPIC) publishes genotype-based drug guidelines to help clinicians understand how available genetic test results could be used to optimize drug therapy. CPIC has focused initially on well-known examples of pharmacogenomic associations that have been implemented in selected clinical settings, publishing nine to date. Each CPIC guideline adheres to a standardized format and includes a standard system for grading levels of evidence linking genotypes to phenotypes and assigning a level of strength to each prescribing recommendation. CPIC guidelines contain the necessary information to help clinicians translate patient-specific diplotypes for each gene into clinical phenotypes or drug dosing groups. This paper reviews the development process of the CPIC guidelines and compares this process to the Institute of Medicine's Standards for Developing Trustworthy Clinical Practice Guidelines.

  20. Personal Genome Sequencing in Ostensibly Healthy Individuals and the PeopleSeq Consortium.

    Science.gov (United States)

    Linderman, Michael D; Nielsen, Daiva E; Green, Robert C

    2016-03-25

    Thousands of ostensibly healthy individuals have had their exome or genome sequenced, but a much smaller number of these individuals have received any personal genomic results from that sequencing. We term those projects in which ostensibly healthy participants can receive sequencing-derived genetic findings and may also have access to their genomic data as participatory predispositional personal genome sequencing (PPGS). Here we are focused on genome sequencing applied in a pre-symptomatic context and so define PPGS to exclude diagnostic genome sequencing intended to identify the molecular cause of suspected or diagnosed genetic disease. In this report we describe the design of completed and underway PPGS projects, briefly summarize the results reported to date and introduce the PeopleSeq Consortium, a newly formed collaboration of PPGS projects designed to collect much-needed longitudinal outcome data.

  1. University-industry consortium: maximizing the use of limited resources for instructor training

    International Nuclear Information System (INIS)

    This proposed development effort would accomplish three major objectives, as follows: 1. To identify and verify, through job analysis, the critical professional tasks that must be performed by electric utility instructors. 2. To adapt and revise existing instructor training modules to make them self-contained and highly specific to the professional knowledge and skills needed by electric utility instructors. 3. To develop new instructor training modules, if needed, to meet utility instructor training needs that are not addressed by any existing materials. It is anticipated that approximately twenty (20) modules will be needed to address all of the critical instructor tasks identified during the job analysis phase. The National Center for Research in Vocational Education proposes that it would be very cost-effective and time-efficient to cooperatively undertake the development of the needed instructor training modules with a consortium of about to ten interested electric utility companies

  2. A campaign to end animal testing: introducing the PETA International Science Consortium Ltd.

    Science.gov (United States)

    Stoddart, Gilly; Brown, Jeffrey

    2014-12-01

    The successful development and validation of non-animal techniques, or the analysis of existing data to satisfy regulatory requirements, provide no guarantee that this information will be used in place of animal experiments. In order to advocate for the replacement of animal-based testing requirements, the PETA International Science Consortium Ltd (PISC) liaises with industry, regulatory and research agencies to establish and promote clear paths to validation and regulatory use of non-animal techniques. PISC and its members use an approach that identifies, promotes and verifies the implementation of good scientific practices in place of testing on animals. Examples of how PISC and its members have applied this approach to minimise the use of animals for the Registration, Evaluation, Authorisation and Restriction of Chemicals regulation in the EU and testing of cosmetics on animals in India, are described. PMID:25635647

  3. Microbial consortium influence upon steel corrosion rate, using the electrochemical impedance spectroscopy technique

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez-Gayosso, M.J.; Ruiz-Ordaz, N. [Escuela Nacional de Ciencias Biologicas, Instituto Politecnico Nacional. Prolongacion de Carpio y Plan de Ayala, Mexico, D.F, C.P. 11340 (Mexico); Zavala-Olivares, G.; Garcia-Esquivel, R. [Instituto Mexicano del Petroleo, Grupo de Corrosion. Eje Central Lazaro Cardenas 152, Col. San Bartolo Atepehuacan, Mexico, D.F, C.P. 07730 (Mexico); Mora-Mendoza, J.L. [Petroleos Mexicanos, Marina Nacional 329, B-1, piso 8, Colonia Huasteca, CP 11311, Mexico, D.F. (Mexico)

    2004-09-01

    The Electrochemical Impedance Technique was used to evaluate the influence of a microbial consortium, isolated from a gas pipeline, upon API XL52 steel corrosion rate. The bacteria growth exhibited two different kinetics behavior, one for the planktonic and the other for the sessile phase. The sessile bacteria were found to be the main responsible for the corrosion rate increment observed during the experiments and no relationship between the planktonic microorganisms and the corrosion rate increment was found. The diagrams obtained from the electrochemical impedance measurements, indicated a biofilm formation and that the system changed from activation to diffusion control. Although the system was under diffusion control, an increment on the corrosion rate was detected, and a localized corrosion process was induced. The results were complemented with some surface analysis using Scanning Electron Microscopy. (Abstract Copyright [2004], Wiley Periodicals, Inc.)

  4. Carrier mounted bacterial consortium facilitates oil remediation in the marine environment.

    Science.gov (United States)

    Simons, Keryn L; Sheppard, Petra J; Adetutu, Eric M; Kadali, Krishna; Juhasz, Albert L; Manefield, Mike; Sarma, Priyangshu M; Lal, Banwari; Ball, Andrew S

    2013-04-01

    Marine oil pollution can result in the persistent presence of weathered oil. Currently, removal of weathered oil is reliant on chemical dispersants and physical removal, causing further disruption. In contrast few studies have examined the potential of an environmentally sustainable method using a hydrocarbon degrading microbial community attached to a carrier. Here, we used a tank mesocosm system (50 l) to follow the degradation of weathered oil (10 g l(-1)) using a bacterial consortium mobilised onto different carrier materials (alginate or shell grit). GCMS analysis demonstrated that the extent of hydrocarbon degradation was dependent upon the carrier material. Augmentation of shell grit with nutrients and exogenous hydrocarbon degraders resulted in 75±14% removal of >C32 hydrocarbons after 12 weeks compared to 20±14% for the alginate carrier. This study demonstrated the effectiveness of a biostimulated and bioaugmented carrier material to degrade marine weathered oil.

  5. A campaign to end animal testing: introducing the PETA International Science Consortium Ltd.

    Science.gov (United States)

    Stoddart, Gilly; Brown, Jeffrey

    2014-12-01

    The successful development and validation of non-animal techniques, or the analysis of existing data to satisfy regulatory requirements, provide no guarantee that this information will be used in place of animal experiments. In order to advocate for the replacement of animal-based testing requirements, the PETA International Science Consortium Ltd (PISC) liaises with industry, regulatory and research agencies to establish and promote clear paths to validation and regulatory use of non-animal techniques. PISC and its members use an approach that identifies, promotes and verifies the implementation of good scientific practices in place of testing on animals. Examples of how PISC and its members have applied this approach to minimise the use of animals for the Registration, Evaluation, Authorisation and Restriction of Chemicals regulation in the EU and testing of cosmetics on animals in India, are described.

  6. Establishing a consortium for Open Access (OA) publishing in particle physics

    CERN Document Server

    Dallman, David Peter; Vigen, Jens; Voss, Rüdiger; Yeomans, Joanne

    2006-01-01

    A meeting has been called at CERN on November 3rd 2006 to work towards establishing a consortium of major particle physics funding agencies, aimed at guiding a transition of the current subscription model for journals to a more stable, more competitive and more affordable future for the dissemination of quality-assured scientific information adapted to the era of electronic publishing. The meeting will gather representatives of major European particle physics agencies and library consortia. In order to be successful it is vital that the stakeholders, representing as they do the funding bodies and academia, see themselves responsible for the financing and organization of the dissemination of scientific information and its quality assurance. In particular the transition to a wider availability of research results cannot afford to be held back due to a lack of concerted effort among the agencies financing the research.

  7. Communication flows in an SME network: the C.I.S.I consortium case

    Science.gov (United States)

    Ceci, Federica; Iubatti, Daniela; Simboli, Alberto

    Networks have been hailed as a third organizational form, between markets and hierarchies. One of the main characteristics of networks is the coexistence of personal and professional relationships. This coexistence modifies the development of economic activities; strategic decisions are largely influenced by the presence of trust between network members. This chapter investigates the role played by personal relationships in enabling the diffusion of innovation within networks. We address the following research questions: How do the different types of relationships in a network of SMEs enable the diffusion and adoption of innovations? Furthermore, do personal relationships play a central role in supporting innovative activities? Based on interviews with managers of SMEs in a consortium of Italian firms, we conclude that interaction between personal and professional relationships shapes a unique context that alters the usual dynamics of innovation diffusion.

  8. Biological management of Sclerotinia sclerotiorum in pea using plant growth promoting microbial consortium.

    Science.gov (United States)

    Jain, Akansha; Singh, Akanksha; Singh, Surendra; Singh, Harikesh Bahadur

    2015-08-01

    The beneficial plant-microbe interactions play crucial roles in protection against large number of plant pathogens causing disease. The present study aims to investigate the growth promoting traits induced by beneficial microbes namely Pseudomonas aeruginosa PJHU15, Trichoderma harzianum TNHU27, and Bacillus subtilis BHHU100 treated singly and in combinations under greenhouse and field conditions to control Sclerotinia sclerotiorum. Plants treated with three microbe consortium enhanced plant growth maximally both in the presence and absence of the pathogen. Increase in plant length, total biomass, number of leaves, nodules and secondary roots, total chlorophyll and carotenoid content, and yield were recorded in plants treated with microbial consortia. Also, a decrease in plant mortality was observed in plants treated with microbial consortia in comparison to untreated control plants challenged with S. sclerotiorum. Furthermore, the decrease in disease of all the treatments can be associated with differential improvement of growth induced in pea. PMID:25727183

  9. Simulating social-ecological systems: the Island Digital Ecosystem Avatars (IDEA) consortium.

    Science.gov (United States)

    Davies, Neil; Field, Dawn; Gavaghan, David; Holbrook, Sally J; Planes, Serge; Troyer, Matthias; Bonsall, Michael; Claudet, Joachim; Roderick, George; Schmitt, Russell J; Zettler, Linda Amaral; Berteaux, Véronique; Bossin, Hervé C; Cabasse, Charlotte; Collin, Antoine; Deck, John; Dell, Tony; Dunne, Jennifer; Gates, Ruth; Harfoot, Mike; Hench, James L; Hopuare, Marania; Kirch, Patrick; Kotoulas, Georgios; Kosenkov, Alex; Kusenko, Alex; Leichter, James J; Lenihan, Hunter; Magoulas, Antonios; Martinez, Neo; Meyer, Chris; Stoll, Benoit; Swalla, Billie; Tartakovsky, Daniel M; Murphy, Hinano Teavai; Turyshev, Slava; Valdvinos, Fernanda; Williams, Rich; Wood, Spencer

    2016-01-01

    Systems biology promises to revolutionize medicine, yet human wellbeing is also inherently linked to healthy societies and environments (sustainability). The IDEA Consortium is a systems ecology open science initiative to conduct the basic scientific research needed to build use-oriented simulations (avatars) of entire social-ecological systems. Islands are the most scientifically tractable places for these studies and we begin with one of the best known: Moorea, French Polynesia. The Moorea IDEA will be a sustainability simulator modeling links and feedbacks between climate, environment, biodiversity, and human activities across a coupled marine-terrestrial landscape. As a model system, the resulting knowledge and tools will improve our ability to predict human and natural change on Moorea and elsewhere at scales relevant to management/conservation actions.

  10. Proposal to establish a Sponsoring Consortium for Open Access Publishing in Particle Physics

    CERN Document Server

    CERN. Geneva

    2007-01-01

    In the present proposal, the publishers' subscription income from multiple institutions is replaced by an "author-side" funding. Journals are paid through contracts between publishers and a single financial partner, the "Sponsoring Consortium for Open Access Publishing in Particle Physics" (SCOAP3). SCOAP3 is envisioned as a global network of funding agencies, research laboratories, and libraries that will contribute the necessary funding; each SCOAP3 partner will recover its contribution from the cancellation of journal subscriptions. This model avoids the obvious disadvantage of authors being directly charged for the OA publication of their articles, which is perceived as an even higher barrier than subscription charges, in particular for theoretical physicists from small institutions who account for the vast majority of HEP papers. The financing and governance of SCOAP3 will follow as much as possible the example of the memoranda of understanding governing large research collaborations. Its partners will c...

  11. The International Consortium for Harmonization of Clinical Laboratory Results (ICHCLR) – A Pathway for Harmonization

    Science.gov (United States)

    Miller, W. Greg

    2016-01-01

    Results from clinical laboratory measurement procedures must be equivalent to enable effective use of clinical guidelines for disease diagnosis and patient management. Analytical results that are harmonized and independent of the measurement system, time, and location of testing is essential for providing adequate patient care. The key to generating harmonized results is establishing traceability to an accepted reference standard where available. Awareness of the benefits of having traceable measurement results that are harmonized has increased along with efforts to develop approaches to enable and facilitate the implementation of harmonization. Although several organizations are addressing harmonization of test procedures, centralized and cooperative global oversight is needed to ensure that the most important tests are being addressed and resources are optimally used. Working with its domestic and international partners, the American Association for Clinical Chemistry (AACC) has created an International Consortium for Harmonization of Clinical Laboratory Results. Advances in this area will improve the quality of patient care.

  12. Analysis of mammalian gene function through broad based phenotypic screens across a consortium of mouse clinics

    Science.gov (United States)

    Adams, David J; Adams, Niels C; Adler, Thure; Aguilar-Pimentel, Antonio; Ali-Hadji, Dalila; Amann, Gregory; André, Philippe; Atkins, Sarah; Auburtin, Aurelie; Ayadi, Abdel; Becker, Julien; Becker, Lore; Bedu, Elodie; Bekeredjian, Raffi; Birling, Marie-Christine; Blake, Andrew; Bottomley, Joanna; Bowl, Mike; Brault, Véronique; Busch, Dirk H; Bussell, James N; Calzada-Wack, Julia; Cater, Heather; Champy, Marie-France; Charles, Philippe; Chevalier, Claire; Chiani, Francesco; Codner, Gemma F; Combe, Roy; Cox, Roger; Dalloneau, Emilie; Dierich, André; Di Fenza, Armida; Doe, Brendan; Duchon, Arnaud; Eickelberg, Oliver; Esapa, Chris T; El Fertak, Lahcen; Feigel, Tanja; Emelyanova, Irina; Estabel, Jeanne; Favor, Jack; Flenniken, Ann; Gambadoro, Alessia; Garrett, Lilian; Gates, Hilary; Gerdin, Anna-Karin; Gkoutos, George; Greenaway, Simon; Glasl, Lisa; Goetz, Patrice; Da Cruz, Isabelle Goncalves; Götz, Alexander; Graw, Jochen; Guimond, Alain; Hans, Wolfgang; Hicks, Geoff; Hölter, Sabine M; Höfler, Heinz; Hancock, John M; Hoehndorf, Robert; Hough, Tertius; Houghton, Richard; Hurt, Anja; Ivandic, Boris; Jacobs, Hughes; Jacquot, Sylvie; Jones, Nora; Karp, Natasha A; Katus, Hugo A; Kitchen, Sharon; Klein-Rodewald, Tanja; Klingenspor, Martin; Klopstock, Thomas; Lalanne, Valerie; Leblanc, Sophie; Lengger, Christoph; le Marchand, Elise; Ludwig, Tonia; Lux, Aline; McKerlie, Colin; Maier, Holger; Mandel, Jean-Louis; Marschall, Susan; Mark, Manuel; Melvin, David G; Meziane, Hamid; Micklich, Kateryna; Mittelhauser, Christophe; Monassier, Laurent; Moulaert, David; Muller, Stéphanie; Naton, Beatrix; Neff, Frauke; Nolan, Patrick M; Nutter, Lauryl MJ; Ollert, Markus; Pavlovic, Guillaume; Pellegata, Natalia S; Peter, Emilie; Petit-Demoulière, Benoit; Pickard, Amanda; Podrini, Christine; Potter, Paul; Pouilly, Laurent; Puk, Oliver; Richardson, David; Rousseau, Stephane; Quintanilla-Fend, Leticia; Quwailid, Mohamed M; Racz, Ildiko; Rathkolb, Birgit; Riet, Fabrice; Rossant, Janet; Roux, Michel; Rozman, Jan; Ryder, Ed; Salisbury, Jennifer; Santos, Luis; Schäble, Karl-Heinz; Schiller, Evelyn; Schrewe, Anja; Schulz, Holger; Steinkamp, Ralf; Simon, Michelle; Stewart, Michelle; Stöger, Claudia; Stöger, Tobias; Sun, Minxuan; Sunter, David; Teboul, Lydia; Tilly, Isabelle; Tocchini-Valentini, Glauco P; Tost, Monica; Treise, Irina; Vasseur, Laurent; Velot, Emilie; Vogt-Weisenhorn, Daniela; Wagner, Christelle; Walling, Alison; Weber, Bruno; Wendling, Olivia; Westerberg, Henrik; Willershäuser, Monja; Wolf, Eckhard; Wolter, Anne; Wood, Joe; Wurst, Wolfgang; Yildirim, Ali Önder; Zeh, Ramona; Zimmer, Andreas; Zimprich, Annemarie

    2015-01-01

    The function of the majority of genes in the mouse and human genomes remains unknown. The mouse ES cell knockout resource provides a basis for characterisation of relationships between gene and phenotype. The EUMODIC consortium developed and validated robust methodologies for broad-based phenotyping of knockouts through a pipeline comprising 20 disease-orientated platforms. We developed novel statistical methods for pipeline design and data analysis aimed at detecting reproducible phenotypes with high power. We acquired phenotype data from 449 mutant alleles, representing 320 unique genes, of which half had no prior functional annotation. We captured data from over 27,000 mice finding that 83% of the mutant lines are phenodeviant, with 65% demonstrating pleiotropy. Surprisingly, we found significant differences in phenotype annotation according to zygosity. Novel phenotypes were uncovered for many genes with unknown function providing a powerful basis for hypothesis generation and further investigation in diverse systems. PMID:26214591

  13. Rhizoremediation of Petrol Engine Oil Using Biosurfactants Producing Microbial Consortium in Mustard Crop

    Directory of Open Access Journals (Sweden)

    Govind Kumar

    2015-06-01

    Full Text Available Contamination of soil / water resources by petroleum products poses severe threats to underground water and soil quality. In the present study biosurfactant producing bacterial cultures were used to degrade petrol engine oil under in situ conditions in the plant rhizosphere system. Two bacterial isolates used in this study were recovered from Haldia oil refinery sites and identified as Pseudomonas aeruginosa (JX100389 and P. moraviensis (JX149542. Application of consortium C2, (Pseudomonas aeruginosa and P. moraviensis degraded 79.02 % petrol engine oil @ 2% in the soil planted with mustard (Brassica juncea var. Kranti crop after 120 days. GC-MS of biodegraded fuel showed the presence of new product like hexadecanoic acid 2, oxo-methyl ester.

  14. Personal Genome Sequencing in Ostensibly Healthy Individuals and the PeopleSeq Consortium

    Science.gov (United States)

    Linderman, Michael D.; Nielsen, Daiva E.; Green, Robert C.

    2016-01-01

    Thousands of ostensibly healthy individuals have had their exome or genome sequenced, but a much smaller number of these individuals have received any personal genomic results from that sequencing. We term those projects in which ostensibly healthy participants can receive sequencing-derived genetic findings and may also have access to their genomic data as participatory predispositional personal genome sequencing (PPGS). Here we are focused on genome sequencing applied in a pre-symptomatic context and so define PPGS to exclude diagnostic genome sequencing intended to identify the molecular cause of suspected or diagnosed genetic disease. In this report we describe the design of completed and underway PPGS projects, briefly summarize the results reported to date and introduce the PeopleSeq Consortium, a newly formed collaboration of PPGS projects designed to collect much-needed longitudinal outcome data. PMID:27023617

  15. 77 FR 38831 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-3D PDF Consortium...

    Science.gov (United States)

    2012-06-29

    ... Section 6(b) of the Act on April 20, 2012 (77 FR 23754). Patricia A. Brink, Director of Civil Enforcement... Antitrust Division Notice Pursuant to the National Cooperative Research and Production Act of 1993--3D PDF... Cooperative Research and Production Act of 1993, 15 U.S.C. 4301 et seq. (``the Act''), 3D PDF Consortium,...

  16. 25 CFR 1000.26 - Under what circumstances will a Tribe/Consortium be removed from the applicant pool?

    Science.gov (United States)

    2010-04-01

    ... removed from the applicant pool? 1000.26 Section 1000.26 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN... Participation in Tribal Self-Governance Admission into the Applicant Pool § 1000.26 Under what circumstances will a Tribe/Consortium be removed from the applicant pool? Once admitted into the applicant pool,...

  17. Effect of CH4/O2 ratio on fatty acid profile and polyhydroxybutyrate content in a heterotrophic-methanotrophic consortium.

    Science.gov (United States)

    Karthikeyan, Obulisamy P; Chidambarampadmavathy, Karthigeyan; Nadarajan, Saravanan; Lee, Patrick K H; Heimann, Kirsten

    2015-12-01

    Understanding the role of heterotrophic-methanotrophic (H-Meth) communities is important for improvement of methane (CH4) oxidation capacities (MOC) particularly in conjunction with bio-product development in industrial bio-filters. Initially, a H-Meth consortium was established and enriched from marine sediments and characterized by next generation sequencing of the 16s rDNA gene. The enriched consortium was subjected to 10-50% CH4 (i.e., 0.20-1.6 CH4/O2 ratios) to study the effects on MOCs, biomass growth, fatty acid profiles and biopolymer (e.g. polyhydroxybutyrate; PHB) content. Methylocystis, Methylophaga and Pseudoxanthomonas dominated the H-Meth consortium. Culture enrichment of the H-Meth consortium resulted in 15-20-folds higher MOC compared to seed sediments. Increasing CH4 concentration (and decreased O2 levels) yielded higher MOCs, but did not improve total fatty acid contents. PHB contents varied between 2.5% and 8.5% independently of CH4/O2 ratios. The results suggest that H-Meth consortia could potentially be used in industrial bio-filters for production of biopolymer/biofuel precursors from CH4. PMID:26247542

  18. The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report.

    Science.gov (United States)

    2016-06-03

    The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium is a novel, interdisciplinary initiative comprised of experts across many fields, including genomics, data analysis, engineering, public health, and architecture. The ultimate goal of the MetaSUB Consortium is to improve city utilization and planning through the detection, measurement, and design of metagenomics within urban environments. Although continual measures occur for temperature, air pressure, weather, and human activity, including longitudinal, cross-kingdom ecosystem dynamics can alter and improve the design of cities. The MetaSUB Consortium is aiding these efforts by developing and testing metagenomic methods and standards, including optimized methods for sample collection, DNA/RNA isolation, taxa characterization, and data visualization. The data produced by the consortium can aid city planners, public health officials, and architectural designers. In addition, the study will continue to lead to the discovery of new species, global maps of antimicrobial resistance (AMR) markers, and novel biosynthetic gene clusters (BGCs). Finally, we note that engineered metagenomic ecosystems can help enable more responsive, safer, and quantified cities.

  19. The International Testicular Cancer Linkage Consortium : A clinicopathologic descriptive analysis of 461 familial malignant testicular germ cell tumor kindred

    NARCIS (Netherlands)

    Mai, Phuong L.; Friedlander, Michael; Tucker, Kathy; Phillips, Kelly-Anne; Hogg, David; Jewett, Michael A. S.; Lohynska, Radka; Daugaard, Gedske; Richard, Stephane; Bonaiti-Pellie, Catherine; Heidenreich, Axel; Albers, Peter; Bodrogi, Istvan; Geczi, Lajos; Olah, Edith; Daly, Peter A.; Guilford, Parry; Fossa, Sophie D.; Heimdal, Ketil; Liubchenko, Ludmila; Tjulandin, Sergei A.; Stoll, Hans; Weber, Walter; Easton, Douglas F.; Dudakia, Darshna; Huddart, Robert; Stratton, Michael R.; Einhorn, Lawrence; Korde, Larissa; Nathanson, Katherine L.; Bishop, Timothy; Rapley, Elizabeth A.; Greene, Mark H.

    2010-01-01

    Objectives: Familial aggregation of testicular germ cell tumor (TGCT) has been reported, but it is unclear if familial TGCT represents a unique entity with distinct clinicopathologic characteristics. Here we describe a collection of familial TGCT cases from an international consortium, in an effort

  20. Healthy Brain Development: Precursor to Learning. National Health/Education Consortium (1st, Baltimore, Maryland, December 6, 1990).

    Science.gov (United States)

    Institute for Educational Leadership, Washington, DC.

    This report presents the proceedings of a consortium at which leading developmental neuroscientists from across the United States and Canada met at Johns Hopkins University to explore the relationship between children's health and learning and to propose policy changes. Early brain development and its relationship to intelligence, learning, and…

  1. 25 CFR 1000.398 - May a Tribe/Consortium invest funds received under a self-governance agreement?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false May a Tribe/Consortium invest funds received under a self-governance agreement? 1000.398 Section 1000.398 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... invest funds received under a self-governance agreement? Yes, self-governance funds may be invested...

  2. 25 CFR 1000.382 - What may the Tribe's/Consortium's annual report on self-governance address?

    Science.gov (United States)

    2010-04-01

    ...-governance address? 1000.382 Section 1000.382 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS... report on self-governance address? (a) The Tribe's/Consortium's annual self-governance report may address... the programs and services funded under self-governance, summarized and annotated as the Tribe may...

  3. The conception of administrators regarding the formation of a healthcare consortium in Pernambuco, Brazil: a case study.

    Science.gov (United States)

    e Silva, Keila S Brito; Bezerra, Adriana Falangola B

    2011-01-01

    The formation of healthcare consortia is a management strategy adopted by a number of cities in Brazil in order to minimize the difficulties the population has in access to services of greater technological complexity. As administrators are the main governmental actors in the promotion of this strategy, the aim of the present study was to identify the motives, expectations and difficulties faced by the mayors, and secretaries of health that make up a healthcare consortium undergoing a formation process in the rural, coastal zone of the state of Pernambuco. A descriptive, qualitative, case study was conducted. Data collection was carried out through semi-structured interviews held with mayors and secretaries of health of the municipalities participating in the consortium. Data were analyzed by means of content analysis, using the NVivo 2.0 software program. The administrators cited difficulty in access to specialized services and the high cost of transporting patients to distant locations for treatment as motives for the formation of the consortium. With the implantation of this healthcare strategy, the expectations are a reduction in costs regarding patient transportation, an increase in access to services of greater complexity, and negotiations with other spheres of government. The main difficulties faced are political-partisan conflicts and excessive bureaucracy. Although there were no considerable divergences in the administrators' perceptions, it was evident that those who initiated the formation of the consortium offered a deeper, more detailed discourse, thereby demonstrating greater involvement when compared to those who offered continuity to the process.

  4. The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium inaugural meeting report.

    Science.gov (United States)

    2016-01-01

    The Metagenomics and Metadesign of the Subways and Urban Biomes (MetaSUB) International Consortium is a novel, interdisciplinary initiative comprised of experts across many fields, including genomics, data analysis, engineering, public health, and architecture. The ultimate goal of the MetaSUB Consortium is to improve city utilization and planning through the detection, measurement, and design of metagenomics within urban environments. Although continual measures occur for temperature, air pressure, weather, and human activity, including longitudinal, cross-kingdom ecosystem dynamics can alter and improve the design of cities. The MetaSUB Consortium is aiding these efforts by developing and testing metagenomic methods and standards, including optimized methods for sample collection, DNA/RNA isolation, taxa characterization, and data visualization. The data produced by the consortium can aid city planners, public health officials, and architectural designers. In addition, the study will continue to lead to the discovery of new species, global maps of antimicrobial resistance (AMR) markers, and novel biosynthetic gene clusters (BGCs). Finally, we note that engineered metagenomic ecosystems can help enable more responsive, safer, and quantified cities. PMID:27255532

  5. Capec Consortium: Effective Academic-Industrial Interactions Strengthened By Surveys and Analyses of Gaps in Properties Modeling

    DEFF Research Database (Denmark)

    O'Connell, John P.; Gani, Rafiqul

    The CAPEC Consortium has operated for many years. Starting with UNIFAC correlations for activity coefficients, the research has branched out to many other properties like critical properties, heats of formation, boiling points, heats of vaporization, and many others. One key to CAPEC's success has...

  6. It Takes a Village to Raise an Information Technology Project: Suggestions on Collaboration from Our 10-Community-College Consortium

    Science.gov (United States)

    Grandgenett, Neal; Thiele, Levi; Pensabene, Tom; McPeak, Brad

    2015-01-01

    This article describes the collaborative evolution of the Midwest Center for Information Technology (MCIT)--which is a consortium of 10 different community colleges across the four states of Nebraska, Iowa, North Dakota, and South Dakota--that was established to improve information technology (IT) education across the region. MCIT has been funded…

  7. Qualitative toxicity assessment of silver nanoparticles on the fresh water bacterial isolates and consortium at low level of exposure concentration.

    Science.gov (United States)

    Kumar, Deepak; Kumari, Jyoti; Pakrashi, Sunandan; Dalai, Swayamprava; Raichur, Ashok M; Sastry, T P; Mandal, A B; Chandrasekaran, N; Mukherjee, Amitava

    2014-10-01

    Silver nanoparticles (AgNPs) pose a high risk of exposure to the natural environment owing to their extensive usage in various consumer products. In the present study we attempted to understand the harmful effect of AgNPs at environmentally relevant low concentration levels (≤1ppm) towards two different freshwater bacterial isolates and their consortium. The standard plate count assay suggested that the AgNPs were toxic towards the fresh water bacterial isolates as well as the consortium, though toxicity was significantly reduced for the cells in the consortium. The oxidative stress assessment and membrane permeability studies corroborated with the toxicity data. The detailed electron microscopic studies suggested the cell degrading potential of the AgNPs, and the FT-IR studies confirmed the involvement of the surface groups in the toxic effects. No significant ion leaching from the AgNPs was observed at the applied concentration levels signifying the dominant role of the particle size, and size distribution in bacterial toxicity. The reduced toxicity for the cells in the consortium than the individual isolates has major significance in further studies on the ecotoxicity of the AgNPs.

  8. The contribution of fermentative bacteria and methanogenic archaea to azo dye reduction by a thermophilic anaerobic consortium

    NARCIS (Netherlands)

    Santos, dos A.B.; Cervantes, F.J.; Madrid, de M.P.; Bok, de F.A.M.; Stams, A.J.M.; Lier, van J.B.

    2006-01-01

    The contribution of fermentative bacteria and methanogenic archaea to azo dye reduction by a thermophilic anaerobic consortium was studied. Additionally, the effects of different electron-donating substrates and the redox mediator riboflavin on dye reduction were assessed by using either a methanoge

  9. Microbial Corrosion in Linepipe Steel Under the Influence of a Sulfate-Reducing Consortium Isolated from an Oil Field

    Science.gov (United States)

    AlAbbas, Faisal M.; Williamson, Charles; Bhola, Shaily M.; Spear, John R.; Olson, David L.; Mishra, Brajendra; Kakpovbia, Anthony E.

    2013-11-01

    This work investigates microbiologically influenced corrosion of API 5L X52 linepipe steel by a sulfate-reducing bacteria (SRB) consortium. The SRB consortium used in this study was cultivated from a sour oil well in Louisiana, USA. 16S rRNA gene sequence analysis indicated that the mixed bacterial consortium contained three phylotypes: members of Proteobacteria ( Desulfomicrobium sp.), Firmicutes ( Clostridium sp.), and Bacteroidetes ( Anaerophaga sp.). The biofilm and the pits that developed with time were characterized using field emission scanning electron microscopy (FE-SEM). In addition, electrochemical impedance spectroscopy (EIS), linear polarization resistance (LPR) and open circuit potential (OCP) were used to analyze the corrosion behavior. Through circuit modeling, EIS results were used to interpret the physicoelectric interactions between the electrode, biofilm and solution interfaces. The results confirmed that extensive localized corrosion activity of SRB is due to a formed biofilm in conjunction with a porous iron sulfide layer on the metal surface. X-ray diffraction (XRD) revealed semiconductive corrosion products predominantly composed of a mixture of siderite (FeCO3), iron sulfide (Fe x S y ), and iron (III) oxide-hydroxide (FeOOH) constituents in the corrosion products for the system exposed to the SRB consortium.

  10. Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics

    DEFF Research Database (Denmark)

    de Angelis, Martin Hrabě; Nicholson, George; Selloum, Mohammed;

    2015-01-01

    The function of the majority of genes in the mouse and human genomes remains unknown. The mouse embryonic stem cell knockout resource provides a basis for the characterization of relationships between genes and phenotypes. The EUMODIC consortium developed and validated robust methodologies for th...

  11. Isolation and Characterization of a Thermophilic Oil-Degrading Bacterial Consortium

    Institute of Scientific and Technical Information of China (English)

    Gu Guizhou; Li Zheng; Zhao Dongfeng; Zhao Chaocheng

    2013-01-01

    In this study, a thermophilic oil-degrading bacterial consortium KO8-2 growing within the temperature range of 45-65℃(with 55℃being the optimum temperature) was isolated from oil-contaminated soil of Karamay in Xinjiang, China. Denaturing gradient gel electrophoresis (DGGE) showed that there were nine strains included in KO8-2, which originated from the genera of Bacillus, Geobacillus and Clostridium. They all belonged to thermophilic bacteria, and had been previously proved as degraders of at least one petroleum fraction. The crude oil degraded by KO8-2 was analyzed by infrared spectrophotometry, hydrocarbon group type analysis and gas chromatography. The results indicated that the bacterial consortium KO8-2 was able to utilize 64.33%of saturates, 27.06%of aromatics, 13.24%of resins and the oil removal efifciency reached up to 58.73%at 55℃when the oil concentration was 10 g/L. Detailed analysis showed that KO8-2 was able to utilize the hydrocarbon components before C19, and the n-alkanes ranging from C20-C33 were signiif-cantly degraded. The ratios of nC17/Pr and nC18/Ph were 3.12 and 3.87, respectively, before degradation, whereas after degradation the ratios reduced to 0.21 and 0.38, respectively. Compared with the control sample, the oil removal efifciency in KO8-2 composting reactor reached 50.12%after a degradation duration of 60 days.

  12. Waste-Management Education and Research Consortium (WERC) annual progress report, 1991--1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-04-07

    In February, 1990, the Secretary of Energy, James Watkins approved a grant for a waste (management) education and research consortium program by New Mexico State University (NMSU) to the US Department of Energy (DOE). This program known by the acronym, WERC'' includes NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology (NMIMT), Navajo Community College, the Los Alamos National Laboratory and the Sandia National Laboratories. The program is designed to provide an integrated approach to the national need via the following: (1) Education in waste management to reach thousands of students by the three Consortium universities and the affiliate college resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. (The term waste or environmental management is used in a broad sense throughout this paper and includes all aspects of environmental management and environmental restoration.) (2) Professional development via teleconference for industry and government. (3) Technology development programs at the leading edge, providing training to students and information to faculty feeding into the education programs. (4) Education and technology development at the campuses, as well as from four field sites. (5) Ties with other multidisciplinary university facilities. (6) Ties with two National Laboratories (Los Alamos Sandia) located in New Mexico, the Oak Ridge Associated Universities and others. (7) Technology transfer and education via an existing fiber optic network, a satellite link, and an existing state-wide extension program. (8) Outreach program of special interest to pre-college students, communities and business and government leaders throughout the United States. This report summarizes the accomplishments and status at the end of the second year.

  13. Waste-Management Education and Research Consortium (WERC) annual progress report, 1991--1992

    Energy Technology Data Exchange (ETDEWEB)

    1992-04-07

    In February, 1990, the Secretary of Energy, James Watkins approved a grant for a waste (management) education and research consortium program by New Mexico State University (NMSU) to the US Department of Energy (DOE). This program known by the acronym, ``WERC`` includes NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology (NMIMT), Navajo Community College, the Los Alamos National Laboratory and the Sandia National Laboratories. The program is designed to provide an integrated approach to the national need via the following: (1) Education in waste management to reach thousands of students by the three Consortium universities and the affiliate college resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. (The term waste or environmental management is used in a broad sense throughout this paper and includes all aspects of environmental management and environmental restoration.) (2) Professional development via teleconference for industry and government. (3) Technology development programs at the leading edge, providing training to students and information to faculty feeding into the education programs. (4) Education and technology development at the campuses, as well as from four field sites. (5) Ties with other multidisciplinary university facilities. (6) Ties with two National Laboratories (Los Alamos & Sandia) located in New Mexico, the Oak Ridge Associated Universities and others. (7) Technology transfer and education via an existing fiber optic network, a satellite link, and an existing state-wide extension program. (8) Outreach program of special interest to pre-college students, communities and business and government leaders throughout the United States. This report summarizes the accomplishments and status at the end of the second year.

  14. Modelling growth of, and removal of Zn and Hg by a wild microalgal consortium

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Cristina M.; Brandao, Teresa R.S.; Castro, Paula M.L. [Universidade Catolica Portuguesa, Porto (Portugal). CBQF/Escola Superior de Biotecnologia; Malcata, F. Xavier [ISMAI - Instituto Superior da Maia, Avioso S. Pedro (Portugal); CIMAR/CIIMAR - Centro Interdisciplinar de Investigacao Marinha e Ambiental, Porto (Portugal)

    2012-04-15

    Microorganisms isolated from sites contaminated with heavy metals usually possess a higher removal capacity than strains from regular cultures. Heavy metal-containing soil samples from an industrial dumpsite in Northern Portugal were accordingly collected; following enrichment under metal stress, a consortium of wild microalgae was obtained. Their ability to grow in the presence of, and their capacity to recover heavy metals was comprehensively studied; the datasets thus generated were fitted to by a combined model of biomass growth and metal uptake, derived from first principles. After exposure to 15 and 25 mg/L Zn{sup 2+} for 6 days, the microalgal consortium reached similar, or higher cell density than the control; however, under 50 and 65 mg/L Zn{sup 2+}, 71% to 84% inhibition was observed. Growth in the presence of Hg{sup 2+} was significantly inhibited, even at a concentration as low as 25 {mu}g/L, and 90% inhibition was observed above 100 {mu}g/L. The maximum amount of Zn{sup 2+} removed was 21.3 mg/L, upon exposure to 25 mg/L for 6 day, whereas the maximum removal of Hg{sup 2+} was 335 {mu}g/L, upon 6 day in the presence of 350 {mu}g/L. The aforementioned mechanistic model was built upon Monod assumptions (including heavy metal inhibition), coupled with Leudeking-Piret relationships between the rates of biomass growth and metal removal. The overall fits were good under all experimental conditions tested, thus conveying a useful tool for rational optimisation of microalga-mediated bioremediation. (orig.)

  15. Waste-Management Education and Research Consortium (WERC) annual progress report, 1991--1992

    International Nuclear Information System (INIS)

    In February, 1990, the Secretary of Energy, James Watkins approved a grant for a waste (management) education and research consortium program by New Mexico State University (NMSU) to the US Department of Energy (DOE). This program known by the acronym, ''WERC'' includes NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology (NMIMT), Navajo Community College, the Los Alamos National Laboratory and the Sandia National Laboratories. The program is designed to provide an integrated approach to the national need via the following: (1) Education in waste management to reach thousands of students by the three Consortium universities and the affiliate college resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. (The term waste or environmental management is used in a broad sense throughout this paper and includes all aspects of environmental management and environmental restoration.) (2) Professional development via teleconference for industry and government. (3) Technology development programs at the leading edge, providing training to students and information to faculty feeding into the education programs. (4) Education and technology development at the campuses, as well as from four field sites. (5) Ties with other multidisciplinary university facilities. (6) Ties with two National Laboratories (Los Alamos ampersand Sandia) located in New Mexico, the Oak Ridge Associated Universities and others. (7) Technology transfer and education via an existing fiber optic network, a satellite link, and an existing state-wide extension program. (8) Outreach program of special interest to pre-college students, communities and business and government leaders throughout the United States. This report summarizes the accomplishments and status at the end of the second year

  16. The Hobbs Oil and Water Experimental Facility of the Waste-Management Education and Research Consortium

    International Nuclear Information System (INIS)

    The Hobbs Oil and Water Experimental (HOWE) Facility came on-line as a research component of the Waste-Management Education and Research Consortium (WERC) when funding for the Consortium became official in late February 1990. As a support facility for WERC, which was established to expand the ability of this nation to manage hazardous, radioactive, and solid wastes through a multidisciplinary approach, HOWE can tap into the expertise that resides at three major New Mexico universities, on Native American community college, and two national laboratories. The intention of the HOWE is to provide education, as well as research and development programs, that reflect concerns of the petroleum industry in the United States. Personnel work to solve environmental problems and assess the impact to the industry of regulatory actions pertaining to those problems. Leadership for the program is provided from the New Mexico Institute of Mining and Technology at Socorro, NM, by Technical Leaders F.D. Martin, Director of the Petroleum Recovery Research Center, and Dr. R.E. Bretz of the petroleum engineering faculty. The HOWE site is administered by Mike DeMarco, Director of the Petroleum Technology Program at the New Mexico Junior College in Hobbs, NM. Currently, the HOWE laboratory is being provided with state-of-the-art equipment to support research projects or field demonstration activities. Programs include research pertaining to groundwater pollution transport processes, slurry-phase bioremediation of oilfield production pit sludges, and treatment of produced brines or contaminated waters. This paper introduces the HOWE and discusses the research programs relevant to the petroleum industry that are presently underway or planned. Future collaborative efforts with industry that are presently underway or planned. Future collaborative efforts with industry groups are being encouraged

  17. Selective Enrichment of a Methanol-Utilizing Consortium Using Pulp and Paper Mill Waste Streams

    Science.gov (United States)

    Mockos, Gregory R.; Smith, William A.; Loge, Frank J.; Thompson, David N.

    Efficient utilization of carbon inputs is critical to the economic viability of the current forest products sector. Input carbon losses occur in various locations within a pulp mill, including losses as volatile organics and wastewater. Opportunities exist to capture this carbon in the form of value-added products such as biodegradable polymers. Wasteactivated sludge from a pulp mill wastewater facility was enriched for 80 days for a methanol-utilizing consortium with the goal of using this consortium to produce biopolymers from methanol-rich pulp mill waste streams. Five enrichment conditions were utilized: three high-methanol streams from the kraft mill foul condensate system, one methanol-amended stream from the mill wastewater plant, and one methanol-only enrichment. Enrichment reactors were operated aerobically in sequencing batch mode at neutral pH and 25°C with a hydraulic residence time and a solids retention time of 4 days. Non-enriched waste activated sludge did not consume methanol or reduce chemical oxygen demand. With enrichment, however, the chemical oxygen demand reduction over 24-h feed/ decant cycles ranged from 79 to 89%, and methanol concentrations dropped below method detection limits. Neither the non-enriched waste-activated sludge nor any of the enrichment cultures accumulated polyhydroxyalkanoates (PHAs) under conditions of nitrogen sufficiency. Similarly, the non-enriched waste activated sludge did not accumulate PHAs under nitrogen-limited conditions. By contrast, enriched cultures accumulated PHAs to nearly 14% on a dry weight basis under nitrogen-limited conditions. This indicates that selectively enriched pulp mill waste activated sludge can serve as an inoculum for PHA production from methanol-rich pulp mill effluents.

  18. An Industrial-Based Consortium to Develop Premium Carbon Products from Coal Final Report - Part 1

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Bruce; Winton, Shea

    2010-12-31

    Since 1998, The Pennsylvania State University successfully managed the Consortium for Premium Carbon Products from Coal (CPCPC), which was a vehicle for industry-driven research on the promotion, development, and transfer of innovative technologies on premium carbon products from coal to the U.S. industry. The CPCPC was an initiative led by Penn State, its cocharter member West Virginia University (WVU), and the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL), who also provided the base funding for the program, with Penn State responsible for consortium management. CPCPC began in 1998 under DOE Cooperative Agreement No. DE-FC26-98FT40350. This agreement ended November 2004 but the CPCPC activity continued under cooperative agreement No. DE-FC26-03NT41874, which started October 1, 2003 and ended December 31, 2010. The objective of the second agreement was to continue the successful operation of the CPCPC. The CPCPC enjoyed tremendous success with its organizational structure, which included Penn State and WVU as charter members, numerous industrial affiliate members, and strategic university affiliate members together with NETL, forming a vibrant and creative team for innovative research in the area of transforming coal to carbon products. The key aspect of CPCPC was its industry-led council that selected proposals submitted by CPCPC members to ensure CPCPC target areas had strong industrial support. CPCPC had 58 member companies and universities engaged over the 7-year period of this contract. Members were from 17 states and five countries outside of the U.S. During this period, the CPCPC Executive Council selected 46 projects for funding. DOE/CPCPC provided $3.9 million in funding or an average of $564,000 per year. The total project costs were $5.45 million with $1.5 million, or ~28% of the total, provided by the members as cost share. Total average project size was $118,000 with $85,900 provided by DOE/CPCPC. In addition to

  19. An Industrial-Based Consortium to Develop Premium Carbon Products from Coal Final Report - Part 4

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Bruce; Shea, Winton

    2010-12-31

    Since 1998, The Pennsylvania State University successfully managed the Consortium for Premium Carbon Products from Coal (CPCPC), which was a vehicle for industry-driven research on the promotion, development, and transfer of innovative technologies on premium carbon products from coal to the U.S. industry. The CPCPC was an initiative led by Penn State, its cocharter member West Virginia University (WVU), and the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL), who also provided the base funding for the program, with Penn State responsible for consortium management. CPCPC began in 1998 under DOE Cooperative Agreement No. DE-FC26-98FT40350. This agreement ended November 2004 but the CPCPC activity continued under cooperative agreement No. DE-FC26-03NT41874, which started October 1, 2003 and ended December 31, 2010. The objective of the second agreement was to continue the successful operation of the CPCPC. The CPCPC enjoyed tremendous success with its organizational structure, which included Penn State and WVU as charter members, numerous industrial affiliate members, and strategic university affiliate members together with NETL, forming a vibrant and creative team for innovative research in the area of transforming coal to carbon products. The key aspect of CPCPC was its industry-led council that selected proposals submitted by CPCPC members to ensure CPCPC target areas had strong industrial support. CPCPC had 58 member companies and universities engaged over the 7-year period of this contract. Members were from 17 states and five countries outside of the U.S. During this period, the CPCPC Executive Council selected 46 projects for funding. DOE/CPCPC provided $3.9 million in funding or an average of $564,000 per year. The total project costs were $5.45 million with $1.5 million, or {approx}28% of the total, provided by the members as cost share. Total average project size was $118,000 with $85,900 provided by DOE/CPCPC. In

  20. An Industrial-Based Consortium to Develop Premium Carbon Products from Coal Final Report - Part 2

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Bruce; Winton, Shea

    2010-12-31

    Since 1998, The Pennsylvania State University successfully managed the Consortium for Premium Carbon Products from Coal (CPCPC), which was a vehicle for industry-driven research on the promotion, development, and transfer of innovative technologies on premium carbon products from coal to the U.S. industry. The CPCPC was an initiative led by Penn State, its cocharter member West Virginia University (WVU), and the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL), who also provided the base funding for the program, with Penn State responsible for consortium management. CPCPC began in 1998 under DOE Cooperative Agreement No. DE-FC26-98FT40350. This agreement ended November 2004 but the CPCPC activity continued under cooperative agreement No. DE-FC26-03NT41874, which started October 1, 2003 and ended December 31, 2010. The objective of the second agreement was to continue the successful operation of the CPCPC. The CPCPC enjoyed tremendous success with its organizational structure, which included Penn State and WVU as charter members, numerous industrial affiliate members, and strategic university affiliate members together with NETL, forming a vibrant and creative team for innovative research in the area of transforming coal to carbon products. The key aspect of CPCPC was its industry-led council that selected proposals submitted by CPCPC members to ensure CPCPC target areas had strong industrial support. CPCPC had 58 member companies and universities engaged over the 7-year period of this contract. Members were from 17 states and five countries outside of the U.S. During this period, the CPCPC Executive Council selected 46 projects for funding. DOE/CPCPC provided $3.9 million in funding or an average of $564,000 per year. The total project costs were $5.45 million with $1.5 million, or ~28% of the total, provided by the members as cost share. Total average project size was $118,000 with $85,900 provided by DOE/CPCPC. In addition to

  1. An Industrial-Based Consortium to Develop Premium Carbon Products from Coal Final Report - Part 5

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Bruce; Shea, Winton

    2010-12-31

    Since 1998, The Pennsylvania State University successfully managed the Consortium for Premium Carbon Products from Coal (CPCPC), which was a vehicle for industry-driven research on the promotion, development, and transfer of innovative technologies on premium carbon products from coal to the U.S. industry. The CPCPC was an initiative led by Penn State, its cocharter member West Virginia University (WVU), and the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL), who also provided the base funding for the program, with Penn State responsible for consortium management. CPCPC began in 1998 under DOE Cooperative Agreement No. DE-FC26-98FT40350. This agreement ended November 2004 but the CPCPC activity continued under cooperative agreement No. DE-FC26-03NT41874, which started October 1, 2003 and ended December 31, 2010. The objective of the second agreement was to continue the successful operation of the CPCPC. The CPCPC enjoyed tremendous success with its organizational structure, which included Penn State and WVU as charter members, numerous industrial affiliate members, and strategic university affiliate members together with NETL, forming a vibrant and creative team for innovative research in the area of transforming coal to carbon products. The key aspect of CPCPC was its industry-led council that selected proposals submitted by CPCPC members to ensure CPCPC target areas had strong industrial support. CPCPC had 58 member companies and universities engaged over the 7-year period of this contract. Members were from 17 states and five countries outside of the U.S. During this period, the CPCPC Executive Council selected 46 projects for funding. DOE/CPCPC provided $3.9 million in funding or an average of $564,000 per year. The total project costs were $5.45 million with $1.5 million, or {approx}28% of the total, provided by the members as cost share. Total average project size was $118,000 with $85,900 provided by DOE/CPCPC. In

  2. An Industrial-Based Consortium to Develop Premium Carbon Products from Coal Final Report - Part 3

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Bruce; Shea, Winton

    2010-12-31

    Since 1998, The Pennsylvania State University successfully managed the Consortium for Premium Carbon Products from Coal (CPCPC), which was a vehicle for industry-driven research on the promotion, development, and transfer of innovative technologies on premium carbon products from coal to the U.S. industry. The CPCPC was an initiative led by Penn State, its cocharter member West Virginia University (WVU), and the U.S. Department of Energy's (DOE) National Energy Technology Laboratory (NETL), who also provided the base funding for the program, with Penn State responsible for consortium management. CPCPC began in 1998 under DOE Cooperative Agreement No. DE-FC26-98FT40350. This agreement ended November 2004 but the CPCPC activity continued under cooperative agreement No. DE-FC26-03NT41874, which started October 1, 2003 and ended December 31, 2010. The objective of the second agreement was to continue the successful operation of the CPCPC. The CPCPC enjoyed tremendous success with its organizational structure, which included Penn State and WVU as charter members, numerous industrial affiliate members, and strategic university affiliate members together with NETL, forming a vibrant and creative team for innovative research in the area of transforming coal to carbon products. The key aspect of CPCPC was its industry-led council that selected proposals submitted by CPCPC members to ensure CPCPC target areas had strong industrial support. CPCPC had 58 member companies and universities engaged over the 7-year period of this contract. Members were from 17 states and five countries outside of the U.S. During this period, the CPCPC Executive Council selected 46 projects for funding. DOE/CPCPC provided $3.9 million in funding or an average of $564,000 per year. The total project costs were $5.45 million with $1.5 million, or ~28% of the total, provided by the members as cost share. Total average project size was $118,000 with $85,900 provided by DOE/CPCPC. In addition to

  3. Mineralization and Detoxification of the Carcinogenic Azo Dye Congo Red and Real Textile Effluent by a Polyurethane Foam Immobilized Microbial Consortium in an Upflow Column Bioreactor

    OpenAIRE

    Harshad Lade; Sanjay Govindwar; Diby Paul

    2015-01-01

    A microbial consortium that is able to grow in wheat bran (WB) medium and decolorize the carcinogenic azo dye Congo red (CR) was developed. The microbial consortium was immobilized on polyurethane foam (PUF). Batch studies with the PUF-immobilized microbial consortium showed complete removal of CR dye (100 mg·L−1) within 12 h at pH 7.5 and temperature 30 ± 0.2 °C under microaerophilic conditions. Additionally, 92% American Dye Manufactureing Institute (ADMI) removal for real textile effluent...

  4. Why might regional vaccinology networks fail? The case of the Dutch-Nordic Consortium.

    Science.gov (United States)

    Hendriks, Jan; Blume, Stuart

    2016-01-01

    We analyzed an attempt to develop and clinically test a pneumococcal conjugate vaccine for the developing world, undertaken by public health institutions from the Netherlands, Sweden, Denmark, Norway and Finland: the Dutch Nordic Consortium (DNC), between 1990 and 2000. Our review shows that the premature termination of the project was due less to technological and scientific challenges and more to managerial challenges and institutional policies. Various impeding events, financial and managerial challenges gradually soured the initially enthusiastic collaborative spirit until near the end the consortium struggled to complete the minimum objectives of the project. By the end of 1998, a tetravalent prototype vaccine had been made that proved safe and immunogenic in Phase 1 trials in adults and toddlers in Finland. The planned next step, to test the vaccine in Asia in infants, did not meet approval by the local authorities in Vietnam nor later in the Philippines and the project eventually stopped.The Dutch DNC member, the National Institute of Public Health and the Environment (RIVM) learned important lessons, which subsequently were applied in a following vaccine technology transfer project, resulting in the availability at affordable prices for the developing world of a conjugate vaccine against Haemophilus influenzae type b. We conclude that vaccine development in the public domain with technology transfer as its ultimate aim requires major front-end funding, committed leadership at the highest institutional level sustained for many years and a competent recipient-manufacturer, which needs to be involved at a very early stage of the development.At the national level, RIVM's policy to consolidate its national manufacturing task through securing a key global health position in support of a network of public vaccine manufacturers proved insufficiently supported by the relevant ministries of the Dutch government. Difficulties to keep up with high costs, high

  5. The Making Assessment Count (MAC consortium maximising assessment and feedback design by working together

    Directory of Open Access Journals (Sweden)

    Mark JP Kerrigan

    2011-02-01

    Full Text Available The Making Assessment Count (MAC project started at the University of Westminster in 2008. It sought to align staff and student expectations of feedback and support greater use of feed-forward approaches. A baseline analysis of staff views in the School of Life Sciences suggested that students did not make strategic use of the feedback they received. A similar analysis of the student position revealed that as a group they felt that the feedback provided to them was often insufficiently helpful. To address this dichotomy, a MAC process was developed in the School of Life Sciences and trialled with a cohort of about 350 first year undergraduate students. The process was based on a student-centred, three-stage model of feedback: Subject specific, Operational, and Strategic (SOS model. The student uses the subject tutor's feedback on an assignment to complete an online self-review questionnaire delivered by a simple tool. The student answers are processed by a web application called e-Reflect to generate a further feedback report. Contained within this report are personalised graphical representations of performance, time management, satisfaction and other operational feedback designed to help the student reflect on their approach to preparation and completion of future work. The student then writes in an online learning journal, which is shared with their personal tutor to support the personal tutorial process and the student's own development plan (PDP. Since the initial development and implementation of the MAC process within Life Sciences at Westminster, a consortium of universities has worked together to maximise the benefits of the project outcomes and collaboratively explore how the SOS model and e-Reflect can be exploited in different institutional and subject contexts. This paper presents and discusses an evaluation of the use of the MAC process within Life Sciences at Westminster from both staff and student perspective. In addition, the

  6. Consortium for Petroleum & Natural Gas Stripper Wells PART 2 OF 3

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, Joel

    2011-12-01

    The United States has more oil and gas wells than any other country. As of December 31, 2004, there were more than half a million producing oil wells in the United States. That is more than three times the combined total for the next three leaders: China, Canada, and Russia. The Stripper Well Consortium (SWC) is a partnership that includes domestic oil and gas producers, service and supply companies, trade associations, academia, the Department of Energy’s Strategic Center for Natural Gas and Oil (SCNGO) at the National Energy Technology Laboratory (NETL), and the New York State Energy Research and Development Authority (NYSERDA). The Consortium was established in 2000. This report serves as a final technical report for the SWC activities conducted over the May 1, 2004 to December 1, 2011 timeframe. During this timeframe, the SWC worked with 173 members in 29 states and three international countries, to focus on the development of new technologies to benefit the U.S. stripper well industry. SWC worked with NETL to develop a nationwide request-for-proposal (RFP) process to solicit proposals from the U.S. stripper well industry to develop and/or deploy new technologies that would assist small producers in improving the production performance of their stripper well operations. SWC conducted eight rounds of funding. A total of 132 proposals were received. The proposals were compiled and distributed to an industrydriven SWC executive council and program sponsors for review. Applicants were required to make a formal technical presentation to the SWC membership, executive council, and program sponsors. After reviewing the proposals and listening to the presentations, the executive council made their funding recommendations to program sponsors. A total of 64 projects were selected for funding, of which 59 were fully completed. Penn State then worked with grant awardees to issue a subcontract for their approved work. SWC organized and hosted a total of 14 meetings

  7. Biodegradation and detoxification of textile azo dyes by bacterial consortium under sequential microaerophilic/aerobic processes.

    Science.gov (United States)

    Lade, Harshad; Kadam, Avinash; Paul, Diby; Govindwar, Sanjay

    2015-01-01

    Release of textile azo dyes to the environment is an issue of health concern while the use of microorganisms has proved to be the best option for remediation. Thus, in the present study, a bacterial consortium consisting of Providencia rettgeri strain HSL1 and Pseudomonas sp. SUK1 has been investigated for degradation and detoxification of structurally different azo dyes. The consortium showed 98-99 % decolorization of all the selected azo dyes viz. Reactive Black 5 (RB 5), Reactive Orange 16 (RO 16), Disperse Red 78 (DR 78) and Direct Red 81 (DR 81) within 12 to 30 h at 100 mg L(-1) concentration at 30 ± 0.2 °C under microaerophilic, sequential aerobic/microaerophilic and microaerophilic/aerobic processes. However, decolorization under microaerophilic conditions viz. RB 5 (0.26 mM), RO 16 (0.18 mM), DR 78 (0.20 mM) and DR 81 (0.23 mM) and sequential aerobic/microaerophilic processes viz. RB 5 (0.08 mM), RO 16 (0.06 mM), DR 78 (0.07 mM) and DR 81 (0.09 mM) resulted into the formation of aromatic amines. In distinction, sequential microaerophilic/ aerobic process doesn't show the formation of amines. Additionally, 62-72 % reduction in total organic carbon content was observed in all the dyes decolorized broths under sequential microaerophilic/aerobic processes suggesting the efficacy of method in mineralization of dyes. Notable induction within the levels of azoreductase and NADH-DCIP reductase (97 and 229 % for RB 5, 55 and 160 % for RO 16, 63 and 196 % for DR 78, 108 and 258 % for DR 81) observed under sequential microaerophilic/aerobic processes suggested their critical involvements in the initial breakdown of azo bonds, whereas, a slight increase in the levels of laccase and veratryl alcohol oxidase confirmed subsequent oxidation of formed amines. Also, the acute toxicity assay with Daphnia magna revealed the nontoxic nature of the dye-degraded metabolites under sequential microaerophilic/aerobic processes. As biodegradation under sequential microaerophilic

  8. Consortium for Petroleum & Natural Gas Stripper Wells PART 3 OF 3

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, Joel

    2011-12-01

    The United States has more oil and gas wells than any other country. As of December 31, 2004, there were more than half a million producing oil wells in the United States. That is more than three times the combined total for the next three leaders: China, Canada, and Russia. The Stripper Well Consortium (SWC) is a partnership that includes domestic oil and gas producers, service and supply companies, trade associations, academia, the Department of Energy’s Strategic Center for Natural Gas and Oil (SCNGO) at the National Energy Technology Laboratory (NETL), and the New York State Energy Research and Development Authority (NYSERDA). The Consortium was established in 2000. This report serves as a final technical report for the SWC activities conducted over the May 1, 2004 to December 1, 2011 timeframe. During this timeframe, the SWC worked with 173 members in 29 states and three international countries, to focus on the development of new technologies to benefit the U.S. stripper well industry. SWC worked with NETL to develop a nationwide request-for-proposal (RFP) process to solicit proposals from the U.S. stripper well industry to develop and/or deploy new technologies that would assist small producers in improving the production performance of their stripper well operations. SWC conducted eight rounds of funding. A total of 132 proposals were received. The proposals were compiled and distributed to an industrydriven SWC executive council and program sponsors for review. Applicants were required to make a formal technical presentation to the SWC membership, executive council, and program sponsors. After reviewing the proposals and listening to the presentations, the executive council made their funding recommendations to program sponsors. A total of 64 projects were selected for funding, of which 59 were fully completed. Penn State then worked with grant awardees to issue a subcontract for their approved work. SWC organized and hosted a total of 14 meetings

  9. Soybean after the consortium corn with tropical forages in the savannah

    Directory of Open Access Journals (Sweden)

    Cássia Maria de Paula Garcia

    2013-12-01

    Full Text Available The biggest limitation to sustainable tillage in the Savannah region is the low biomass accumulation during autumn up to spring, due to low water availability and high temperatures characterizing these regions as having a warm and dry winter. The consortium of grains crops with tropical forages mainly of the genus Panicum and Urochloa is an alternative, to this situation. This study aimed to evaluate the effect of the straw production of Panicum and Urochloa after consortium with corn in the crop-livestock integration system on the soybean crop irrigated in succession. The experiment was conducted at the Farm for Teaching, Research and Extension, Faculty of Engineering - UNESP, Ilha Solteira in an Oxisol in Savannah conditions, being in no-tillage for 8 years (previous corn crop. The experimental design was a randomized block with four replications and four treatments: Panicum maximum cv. Tanzania sown during the nitrogen fertilization (CTD of the corn; Panicum maximum cv. Mombasa sown during the nitrogen fertilization (CMD of the corn; Urochloa brizantha cv. Xaraés sown during the occasion of nitrogen fertilization (CBD of the corn; Urochloa ruziziensis cv. Comum sown during the nitrogen fertilization (CRD of the corn. After harvesting the corn and forages cuts, soybean was planted with seeds inoculated with Bradyrhizobium japonicum (Turfy with 600,000 viable cells/seed, at distances of 0.45 m with 24 seeds-1 in the no tillage system (NTS. The height of the first pod, plant population and yield components of soybean (number of pods per plant, number of seeds per pod and mass of 100 grains and grain yield of soybean were not significantly influenced by the straws of forages. These results were found, probably because the area already has a history of tillage for 8 years since this system was stabilized in the area. Therefore, in this soil that was managed correctly, the straw production of the forage of genus Panicum and Urochloa does not

  10. ESTABLISHMENT OF AN INDUSTRY-DRIVEN CONSORTIUM FOCUSED ON IMPROVING THE PRODUCTION PERFORMANCE OF DOMESTIC STRIPPER WELLS

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison

    2003-04-08

    The Pennsylvania State University, under contract to the U.S. Department of Energy, National Energy Technology Laboratory will establish, promote, and manage a national industry-driven Stripper Well Consortium (SWC) that will be focused on improving the production performance of domestic petroleum and/or natural gas stripper wells. The consortium creates a partnership with the U.S. petroleum and natural gas industries and trade associations, state funding agencies, academia, and the National Energy Technology Laboratory. This report serves as the ninth quarterly technical progress report for the SWC. Key activities for this reporting period include: (1) organizing and hosting two fall technology transfer meetings, (2) SWC membership class expansion, and (3) planning the SWC 2003 Spring meeting. In addition, a literature search that focuses on the use of lasers, microwaves, and acoustics for potential stripper well applications continued.

  11. ESTABLISHMENT OF AN INDUSTRY-DRIVEN CONSORTIUM FOCUSED ON IMPROVING THE PRODUCTION PERFORMANCE OF DOMESTIC STRIPPER WELLS

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison

    2004-12-23

    The Pennsylvania State University, under contract to the U.S. Department of Energy, National Energy Technology Laboratory will establish, promote, and manage a national industry-driven Stripper Well Consortium (SWC) that will be focused on improving the production performance of domestic petroleum and/or natural gas stripper wells. The consortium creates a partnership with the U.S. petroleum and natural gas industries and trade associations, state funding agencies, academia, and the National Energy Technology Laboratory. This report serves as the fifteenth quarterly technical progress report for the SWC. Key activities for this reporting period include: (1) hosting the SWC spring proposal meeting in Golden Colorado, (2) planning of the upcoming SWC fall technology transfer meetings, and (3) recruiting the SWC base membership.

  12. ESTABLISHMENT OF AN INDUSTRY-DRIVEN CONSORTIUM FOCUSED ON IMPROVING THE PRODUCTION PERFORMANCE OF DOMESTIC STRIPPER WELLS

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison

    2004-12-28

    The Pennsylvania State University, under contract to the U.S. Department of Energy, National Energy Technology Laboratory will establish, promote, and manage a national industry-driven Stripper Well Consortium (SWC) that will be focused on improving the production performance of domestic petroleum and/or natural gas stripper wells. The consortium creates a partnership with the U.S. petroleum and natural gas industries and trade associations, state funding agencies, academia, and the National Energy Technology Laboratory. This report serves as the first quarterly technical progress report for the SWC. Key activities for this reporting period include: (1) hosting the SWC spring proposal meeting in Golden Colorado, (2) planning of the upcoming SWC fall technology transfer meetings, and (3) recruiting the SWC base membership.

  13. A University Consortium on Low Temperature Combustion for High Efficiency, Ultra-Low Emission Engines

    Energy Technology Data Exchange (ETDEWEB)

    Assanis, Dennis N. [Univ. of Michigan, Ann Arbor, MI (United States); Atreya, Arvind [Univ. of Michigan, Ann Arbor, MI (United States); Chen, Jyh-Yuan [Univ. of California, Berkeley, CA (United States); Cheng, Wai K. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Dibble, Robert W. [Univ. of California, Berkeley, CA (United States); Edwards, Chris [Stanford Univ., CA (United States); Filipi, Zoran S. [Univ. of Michigan, Ann Arbor, MI (United States); Gerdes, Christian [Stanford Univ., CA (United States); Im, Hong [Univ. of Michigan, Ann Arbor, MI (United States); Lavoie, George A. [Univ. of Michigan, Ann Arbor, MI (United States); Wooldridge, Margaret S. [Univ. of Michigan, Ann Arbor, MI (United States)

    2009-12-31

    The objective of the University consortium was to investigate the fundamental processes that determine the practical boundaries of Low Temperature Combustion (LTC) engines and develop methods to extend those boundaries to improve the fuel economy of these engines, while operating with ultra low emissions. This work involved studies of thermal effects, thermal transients and engine management, internal mixing and stratification, and direct injection strategies for affecting combustion stability. This work also examined spark-assisted Homogenous Charge Compression Ignition (HCCI) and exhaust after-treatment so as to extend the range and maximize the benefit of Homogenous Charge Compression Ignition (HCCI)/ Partially Premixed Compression Ignition (PPCI) operation. In summary the overall goals were; Investigate the fundamental processes that determine the practical boundaries of Low Temperature Combustion (LTC) engines; Develop methods to extend LTC boundaries to improve the fuel economy of HCCI engines fueled on gasoline and alternative blends, while operating with ultra low emissions; and Investigate alternate fuels, ignition and after-treatment for LTC and Partially Premixed compression Ignition (PPCI) engines.

  14. Standardizing Flow Cytometry Immunophenotyping Analysis from the Human ImmunoPhenotyping Consortium

    Science.gov (United States)

    Finak, Greg; Langweiler, Marc; Jaimes, Maria; Malek, Mehrnoush; Taghiyar, Jafar; Korin, Yael; Raddassi, Khadir; Devine, Lesley; Obermoser, Gerlinde; Pekalski, Marcin L.; Pontikos, Nikolas; Diaz, Alain; Heck, Susanne; Villanova, Federica; Terrazzini, Nadia; Kern, Florian; Qian, Yu; Stanton, Rick; Wang, Kui; Brandes, Aaron; Ramey, John; Aghaeepour, Nima; Mosmann, Tim; Scheuermann, Richard H.; Reed, Elaine; Palucka, Karolina; Pascual, Virginia; Blomberg, Bonnie B.; Nestle, Frank; Nussenblatt, Robert B.; Brinkman, Ryan Remy; Gottardo, Raphael; Maecker, Holden; McCoy, J Philip

    2016-01-01

    Standardization of immunophenotyping requires careful attention to reagents, sample handling, instrument setup, and data analysis, and is essential for successful cross-study and cross-center comparison of data. Experts developed five standardized, eight-color panels for identification of major immune cell subsets in peripheral blood. These were produced as pre-configured, lyophilized, reagents in 96-well plates. We present the results of a coordinated analysis of samples across nine laboratories using these panels with standardized operating procedures (SOPs). Manual gating was performed by each site and by a central site. Automated gating algorithms were developed and tested by the FlowCAP consortium. Centralized manual gating can reduce cross-center variability, and we sought to determine whether automated methods could streamline and standardize the analysis. Within-site variability was low in all experiments, but cross-site variability was lower when central analysis was performed in comparison with site-specific analysis. It was also lower for clearly defined cell subsets than those based on dim markers and for rare populations. Automated gating was able to match the performance of central manual analysis for all tested panels, exhibiting little to no bias and comparable variability. Standardized staining, data collection, and automated gating can increase power, reduce variability, and streamline analysis for immunophenotyping. PMID:26861911

  15. The National Astronomy Consortium Summer Student Research Program at NRAO-Socorro: Year 2 structure

    Science.gov (United States)

    Mills, Elisabeth A.; Sheth, Kartik; Giles, Faye; Perez, Laura M.; Arancibia, Demian; Burke-Spolaor, Sarah

    2016-01-01

    I will present a summary of the program structure used for the second year of hosting a summer student research cohort of the National Astronomy Consortium (NAC) at the National Radio Astronomy Observatory in Socorro, NM. The NAC is a program partnering physics and astronomy departments in majority and minority-serving institutions across the country. The primary aim of this program is to support traditionally underrepresented students interested in pursuing a career in STEM through a 9-10 week summer astronomy research project and a year of additional mentoring after they return to their home institution. I will describe the research, professional development, and inclusivity goals of the program, and show how these were used to create a weekly syllabus for the summer. I will also highlight several unique aspects of this program, including the recruitment of remote mentors for students to better balance the gender and racial diversity of available role models for the students, as well as the hosting of a contemporaneous series of visiting diversity speakers. Finally, I will discuss structures for continuing to engage, interact with, and mentor students in the academic year following the summer program. A goal of this work going forward is to be able to make instructional and organizational materials from this program available to other sites interested in joining the NAC or hosting similar programs at their own institution.

  16. Industrial Consortium for the Utilization of the Geopressured-Geothermal Resource. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Negus-deWys, J. (ed.)

    1990-03-01

    The Geopressured-Geothermal Program, now in its fifteenth year, is entering the transition period to commercial use. The industry cost-shared proposals to the consortium, represented in the presentations included in these proceedings, attest to the interest developing in the industrial community in utilizing the geopressured-geothermal resource. Sixty-five participants attended these sessions, two-thirds of whom represented industry. The areas represented by cost-shared proposals include (1) thermal enhanced oil recovery, (2) direct process use of thermal energy, e.g., aquaculture and agriculture, (3) conversion of thermal energy to electricity, (4) environment related technologies, e.g., use of supercritical processes, and (5) operational proposals, e.g., a field manual for scale inhibitors. It is hoped that from this array of potential use projects, some will persist and be successful in proving the viability of using the geopressured-geothermal resource. Such industrial use of an alternative and relatively clean energy resource will benefit our nation and its people.

  17. The first pilot project of the consortium for top-down proteomics: A status report

    Energy Technology Data Exchange (ETDEWEB)

    Dang, Xibei [Ion Cyclotron Resonance Program, National High Magnetic Field Laboratory, Florida State University, Tallahassee FL USA; Department of Chemistry and Biochemistry, Florida State University, Tallahassee FL USA; Scotcher, Jenna [Ion Cyclotron Resonance Program, National High Magnetic Field Laboratory, Florida State University, Tallahassee FL USA; Wu, Si [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland WA USA; Chu, Rosalie K. [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland WA USA; Tolić, Nikola [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland WA USA; Ntai, Ioanna [Departments of Chemistry and Molecular Biosciences and the Proteomics Center of Excellence, Northwestern University, Evanston IL USA; Thomas, Paul M. [Departments of Chemistry and Molecular Biosciences and the Proteomics Center of Excellence, Northwestern University, Evanston IL USA; Fellers, Ryan T. [Departments of Chemistry and Molecular Biosciences and the Proteomics Center of Excellence, Northwestern University, Evanston IL USA; Early, Bryan P. [Departments of Chemistry and Molecular Biosciences and the Proteomics Center of Excellence, Northwestern University, Evanston IL USA; Zheng, Yupeng [Departments of Chemistry and Molecular Biosciences and the Proteomics Center of Excellence, Northwestern University, Evanston IL USA; Durbin, Kenneth R. [Departments of Chemistry and Molecular Biosciences and the Proteomics Center of Excellence, Northwestern University, Evanston IL USA; LeDuc, Richard D. [NIH/NCRR Mass Spectrometry Resource, Washington University in St. Louis, St. Louis MO USA; Wolff, Jeremy J. [Bruker Daltonics, Billerica MA USA; Thompson, Christopher J. [Bruker Daltonics, Billerica MA USA; Pan, Jingxi [UVic-Genome BC Proteomics Centre, Department of Biochemistry and Microbiology, University of Victoria, Victoria BC Canada; Han, Jun [UVic-Genome BC Proteomics Centre, Department of Biochemistry and Microbiology, University of Victoria, Victoria BC Canada; Shaw, Jared B. [Department of Chemistry, University of Texas, Austin TX USA; Salisbury, Joseph P. [Departments of Chemistry and Pharm. Sci., Barnett Institute, Northeastern University, Boston MA USA; Easterling, Michael [Bruker Daltonics, Billerica MA USA; Borchers, Christoph H. [UVic-Genome BC Proteomics Centre, Department of Biochemistry and Microbiology, University of Victoria, Victoria BC Canada; Brodbelt, Jennifer S. [Department of Chemistry, University of Texas, Austin TX USA; Agar, Jeffery N. [Departments of Chemistry and Pharm. Sci., Barnett Institute, Northeastern University, Boston MA USA; Paša-Tolić, Ljiljana [Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland WA USA; Kelleher, Neil L. [Departments of Chemistry and Molecular Biosciences and the Proteomics Center of Excellence, Northwestern University, Evanston IL USA; Young, Nicolas L. [Ion Cyclotron Resonance Program, National High Magnetic Field Laboratory, Florida State University, Tallahassee FL USA

    2014-04-14

    Pilot Project #1—the identification and characterization of human histone H4 proteoforms by top-down MS—is the first project launched by the Consortium for Top-Down Proteomics (CTDP) to refine and validate top-down MS. Within the initial results from seven participating laboratories, all reported the probability-based identification of human histone H4 (UniProt accession P62805) with expectation values ranging from 10-13 to 10-105. Regarding characterization, a total of 74 proteoforms were reported, with 21 done so unambiguously; one new PTM, K79ac, was identified. Inter-laboratory comparison reveals aspects of the results that are consistent, such as the localization of individual PTMs and binary combinations, while other aspects are more variable, such as the accurate characterization of low-abundance proteoforms harboring >2 PTMs. An open-access tool and discussion of proteoform scoring are included, along with a description of general challenges that lie ahead including improved proteoform separations prior to mass spectrometric analysis, better instrumentation performance, and software development.

  18. Utilising the resources of the International Knockout Mouse Consortium: the Australian experience.

    Science.gov (United States)

    Cotton, Leanne M; Meilak, Michelle L; Templeton, Tanya; Gonzales, Jose G; Nenci, Arianna; Cooney, Melissa; Truman, Dirk; Rodda, Fleur; Lynas, Alyce; Viney, Elizabeth; Rosenthal, Nadia; Bianco, Deborah M; O'Bryan, Moira K; Smyth, Ian M

    2015-04-01

    Mouse models play a key role in the understanding gene function, human development and disease. In 2007, the Australian Government provided funding to establish the Monash University embryonic stem cell-to-mouse (ES2M) facility. This was part of the broader Australian Phenomics Network, a national infrastructure initiative aimed at maximising access to global resources for understanding gene function in the mouse. The remit of the ES2M facility is to provide subsidised access for Australian biomedical researchers to the ES cell resources available from the International Knockout Mouse Consortium (IKMC). The stated aim of the IKMC is to generate a genetically modified mouse ES cell line for all of the ~23,000 genes in the mouse genome. The principal function of the Monash University ES2M service is to import genetically modified ES cells into Australia and to convert them into live mice with the potential to study human disease. Through advantages of economy of scale and established relationships with ES cell repositories worldwide, we have created over 110 germline mouse strains sourced from all of the major ES providers worldwide. We comment on our experience in generating these mouse lines; providing a snapshot of a "clients" perspective of using the IKMC resource and one which we hope will serve as a guide to other institutions or organisations contemplating establishing a similar centralised service. PMID:25645994

  19. Degradation Characteristics and Community Structure of a Hydrocarbon Degrading Bacterial Consortium

    Institute of Scientific and Technical Information of China (English)

    Li Zheng; Gu Guizhou; Zhao Chaocheng; Zhao Dongfeng

    2015-01-01

    A hydrocarbon degrading bacterial consortium KO5-2 was isolated from oil-contaminated soil of Karamay in Xinjiang, China, which could remove 56.9%of 10 g/L total petroleum hydrocarbons (TPH) at 30℃after 7 days of incu-bation, and could also remove 100%of lfuorene, 98.93%of phenanthrene and 65.73%of pyrene within 3, 7 and 9 days, respectively. Twelve strains from six different genera were isolated from KO5-2 and only eight ones were able to utilize the TPH. The denaturing gradient gel electrophoresis (DGGE) was used to investigate the microbial community shifts in ifve different carbon sources (including TPH, saturated hydrocarbons, lfuorene, phenanthrene and pyrene). The test results indi-cated that the community compositions of KO5-2 in carbon sources of TPH and saturated hydrocarbons, respectively, were roughly the same, while they were distinctive in the three different carbon sources of PAHs. Rhodococcus sp. and Pseudo-monas sp. could survive in the ifve kinds of carbon sources. Bacillus sp., Sphingomonas sp. and Ochrobactrum sp. likely played key roles in the degradation of saturated hydrocarbons, PAHs and phenanthrene, respectively. This study showed that speciifc bacterial phylotypes were associated with different contaminants and complex interactions between bacterial spe-cies, and the medium conditions inlfuenced the biodegradation capacity of the microbial communities involved in bioreme-diation processes.

  20. Bioremediation of soil heavily contaminated with crude oil and its products: composition of the microbial consortium

    Directory of Open Access Journals (Sweden)

    JELENA S. MILIĆ

    2009-04-01

    Full Text Available Bioremediation, a process that utilizes the capability of microorganism to degrade toxic waste, is emerging as a promising technology for the treatment of soil and groundwater contamination. The technology is very effective in dealing with petroleum hydrocarbon contamination. The aim of this study was to examine the composition of the microbial consortium during the ex situ experiment of bioremediation of soil heavily contaminated with crude oil and its products from the Oil Refinery Pančevo, Serbia. After a 5.5-month experiment with biostimulation and bioventilation, the concentration of the total petroleum hydrocarbons (TPH had been reduced from 29.80 to 3.29 g/kg (89 %. In soil, the dominant microorganism population comprised Gram-positive bacteria from actinomycete-Nocardia group. The microorganisms which decompose hydrocarbons were the dominant microbial population at the end of the process, with a share of more than 80 % (range 107 CFU/g. On the basis of the results, it was concluded that a stable microbial community had been formed after initial fluctuations.

  1. Indiana Advanced Electric Vehicle Training and Education Consortium (I-AEVtec)

    Energy Technology Data Exchange (ETDEWEB)

    Caruthers, James; Dietz, J.; Pelter, Libby; Chen, Jie; Roberson, Glen; McGinn, Paul; Kizhanipuram, Vinodegopal

    2013-01-31

    The Indiana Advanced Electric Vehicle Training and Education Consortium (I-AEVtec) is an educational partnership between six universities and colleges in Indiana focused on developing the education materials needed to support electric vehicle technology. The I-AEVtec has developed and delivered a number of degree and certificate programs that address various aspects of electric vehicle technology, including over 30 new or significantly modified courses to support these programs. These courses were shared on the SmartEnergyHub. The I-AEVtec program also had a significant outreach to the community with particular focus on K12 students. Finally, the evGrandPrix was established which is a university/college student electric go-kart race, where the students get hands-on experience in designing, building and racing electric vehicles. The evGrandPrix now includes student teams from across the US as well as from Europe and it is currently being held on Opening Day weekend for the Indy500 at the Indianapolis Motor Speedway.

  2. Clinical practice of image-guided spine radiosurgery - results from an international research consortium

    Directory of Open Access Journals (Sweden)

    Guckenberger Matthias

    2011-12-01

    Full Text Available Abstract Background Spinal radiosurgery is a quickly evolving technique in the radiotherapy and neurosurgical communities. However, the methods of spine radiosurgery have not been standardized. This article describes the results of a survey about the methods of spine radiosurgery at five international institutions. Methods All institutions are members of the Elekta Spine Radiosurgery Research Consortium and have a dedicated research and clinical focus on image-guided radiosurgery. The questionnaire consisted of 75 items covering all major steps of spine radiosurgery. Results Strong agreement in the methods of spine radiosurgery was observed. In particular, similarities were observed with safety and quality assurance playing an important role in the methods of all institutions, cooperation between neurosurgeons and radiation oncologists in case selection, dedicated imaging for target- and organ-at-risk delineation, application of proper safety margins for the target volume and organs-at-risk, conformal planning and precise image-guided treatment delivery, and close clinical and radiological follow-up. In contrast, three major areas of uncertainty and disagreement were identified: 1 Indications and contra-indications for spine radiosurgery; 2 treatment dose and fractionation and 3 tolerance dose of the spinal cord. Conclusions Results of this study reflect the current practice of spine radiosurgery in large academic centers. Despite close agreement was observed in many steps of spine radiosurgery, further research in form of retrospective and especially prospective studies is required to refine the details of spinal radiosurgery in terms of safety and efficacy.

  3. Final Technical Report for the Net-Zero Energy Commercial Buildings Consortium

    Energy Technology Data Exchange (ETDEWEB)

    Fazeli, Sandy [National Association of State Energy Officials, Arlington, VA (United States)

    2014-09-30

    The Commercial Buildings Consortium (CBC) was established in 2009, under the chairmanship of the National Association of State Energy Officials (NASEO), as a supporting organization to the Commercial Buildings Initiative (CBI). The CBI was created by Congress through the Energy Independence and Security Act of 2007 (EISA) and launched by the Department of Energy (DOE) in 2008 with the goal to “develop and disseminate technologies, practices, and policies for establishment of zero net energy commercial buildings.”. The impact of the CBC since 2009 has been multifold, resulting in increased collaboration, increased innovation, and increased demonstration and deployment. During the project performance period of 2009-2014, the CBC provided an organizational framework for sustained public-private collaboration among more than 600 commercial building professionals, researchers and educators, utilities, and government agencies at federal, state, and local level. The CBC’s research has identified emerging technologies, market strategies, and innovative public and corporate policies to help advance CBI’s zero-net-energy. Finally, the CBC worked in close partnership with DOE’s commercial building teams and the Better Buildings Alliances to identify opportunities for proving out and deploying energy-saving technologies and practices.

  4. Effect of whey fermented by Enterococcus faeciumin consortium with Veilonella parvulaon ruminal bacteria in vitro

    Directory of Open Access Journals (Sweden)

    Higor Fábio Carvalho Bezerra

    2014-05-01

    Full Text Available The objective of this research was to evaluate the effect of whey fermented by Enterococus faecium in consortium with Veilonella parvula in vitro on ruminal microorganisms in different substrates, with or without monensin. The first experiment was carried out in a completely randomized design, in a 6 × 3 factorial arrangement (six substrates × three whey levels with two replicates. In experiment two, a 2 × 3 × 4 factorial arrangement (with and without monensin, three foods and four levels of fermented whey was used, in a randomized design with four replicates, totaling 24 treatments. There was no interaction among the wheys and the substrates in the variable for pectin, starch, and carboxymethyl cellulose. There was a greater growth of amylolytic and pectinolytic microorganisms and a lower growth of proteolytic and cellulolytic microorganisms. A significant effect of optical density was found in the media without substrate and that containing trypticase and glucose due to the addition of fermented whey. There was interaction for the pH at 24 hours among whey, food and monensin. For ammonia at 24 hours there was effect for food, whey and monensin, and interaction among factors. For microbial protein at 24 hours, there was effect for food, whey, monensin and no interaction among sources of variation. The use of whey fermented by bacteria Enterococcus faeciumand Veilonella parvula improves microbial protein synthesis by ruminal bacteria in media containing different energy sources. The combination of fermented whey and monensin shows variable results in relation to microbial growth.

  5. Diet and the risk of head and neck cancer: a pooled analysis in the INHANCE consortium.

    LENUS (Irish Health Repository)

    Chuang, Shu-Chun

    2012-01-01

    We investigated the association between diet and head and neck cancer (HNC) risk using data from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. The INHANCE pooled data included 22 case-control studies with 14,520 cases and 22,737 controls. Center-specific quartiles among the controls were used for food groups, and frequencies per week were used for single food items. A dietary pattern score combining high fruit and vegetable intake and low red meat intake was created. Odds ratios (OR) and 95% confidence intervals (CI) for the dietary items on the risk of HNC were estimated with a two-stage random-effects logistic regression model. An inverse association was observed for higher-frequency intake of fruit (4th vs. 1st quartile OR = 0.52, 95% CI = 0.43-0.62, p (trend) < 0.01) and vegetables (OR = 0.66, 95% CI = 0.49-0.90, p (trend) = 0.01). Intake of red meat (OR = 1.40, 95% CI = 1.13-1.74, p (trend) = 0.13) and processed meat (OR = 1.37, 95% CI = 1.14-1.65, p (trend) < 0.01) was positively associated with HNC risk. Higher dietary pattern scores, reflecting high fruit\\/vegetable and low red meat intake, were associated with reduced HNC risk (per score increment OR = 0.90, 95% CI = 0.84-0.97).

  6. Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium

    Directory of Open Access Journals (Sweden)

    Nathan Salomonis

    2016-07-01

    Full Text Available The rigorous characterization of distinct induced pluripotent stem cells (iPSC derived from multiple reprogramming technologies, somatic sources, and donors is required to understand potential sources of variability and downstream potential. To achieve this goal, the Progenitor Cell Biology Consortium performed comprehensive experimental and genomic analyses of 58 iPSC from ten laboratories generated using a variety of reprogramming genes, vectors, and cells. Associated global molecular characterization studies identified functionally informative correlations in gene expression, DNA methylation, and/or copy-number variation among key developmental and oncogenic regulators as a result of donor, sex, line stability, reprogramming technology, and cell of origin. Furthermore, X-chromosome inactivation in PSC produced highly correlated differences in teratoma-lineage staining and regulator expression upon differentiation. All experimental results, and raw, processed, and metadata from these analyses, including powerful tools, are interactively accessible from a new online portal at https://www.synapse.org to serve as a reusable resource for the stem cell community.

  7. Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium.

    Science.gov (United States)

    Salomonis, Nathan; Dexheimer, Phillip J; Omberg, Larsson; Schroll, Robin; Bush, Stacy; Huo, Jeffrey; Schriml, Lynn; Ho Sui, Shannan; Keddache, Mehdi; Mayhew, Christopher; Shanmukhappa, Shiva Kumar; Wells, James; Daily, Kenneth; Hubler, Shane; Wang, Yuliang; Zambidis, Elias; Margolin, Adam; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Aronow, Bruce J; Lutzko, Carolyn

    2016-07-12

    The rigorous characterization of distinct induced pluripotent stem cells (iPSC) derived from multiple reprogramming technologies, somatic sources, and donors is required to understand potential sources of variability and downstream potential. To achieve this goal, the Progenitor Cell Biology Consortium performed comprehensive experimental and genomic analyses of 58 iPSC from ten laboratories generated using a variety of reprogramming genes, vectors, and cells. Associated global molecular characterization studies identified functionally informative correlations in gene expression, DNA methylation, and/or copy-number variation among key developmental and oncogenic regulators as a result of donor, sex, line stability, reprogramming technology, and cell of origin. Furthermore, X-chromosome inactivation in PSC produced highly correlated differences in teratoma-lineage staining and regulator expression upon differentiation. All experimental results, and raw, processed, and metadata from these analyses, including powerful tools, are interactively accessible from a new online portal at https://www.synapse.org to serve as a reusable resource for the stem cell community.

  8. The National Astronomy Consortium (NAC) - the University of Wisconsin-Madison Cohort

    Science.gov (United States)

    Hooper, Eric; Sheth, Kartik; Mills, Elisabeth A. C.; National Astronomy Consortium

    2015-01-01

    The UW-Madison Research Experiences for Undergraduates (REU) program in astrophysics (http://www.astro.wisc.edu/undergrads/uw-madison-reu-program/) is partnering with the National Radio Astronomy Observatory, the National Society of Black Physicists, and other universities in an entity called the National Astronomy Consortium (NAC; see https://sites.google.com/site/nraonac/). The mission of the NAC is to increase the numbers of students who might otherwise be overlooked by the traditional academic pipeline into STEM, or related, careers. This begins with a cohort of students who are part of the regular REU program. In addition to working on original research projects under the mentorship of university astronomers and astrophysics, the cohort students participate in professional development seminars and join other NAC cohort sites in a diversity speaker series. The mentor-student and student-student connections continue beyond the summer, including a fall meeting of the national NAC cohorts. The UW-Madison REU program is supported by the National Science Foundation through Award AST-1004881.

  9. Synergistic microbial consortium for bioenergy generation from complex natural energy sources.

    Science.gov (United States)

    Wang, Victor Bochuan; Yam, Joey Kuok Hoong; Chua, Song-Lin; Zhang, Qichun; Cao, Bin; Chye, Joachim Loo Say; Yang, Liang

    2014-01-01

    Microbial species have evolved diverse mechanisms for utilization of complex carbon sources. Proper combination of targeted species can affect bioenergy production from natural waste products. Here, we established a stable microbial consortium with Escherichia coli and Shewanella oneidensis in microbial fuel cells (MFCs) to produce bioenergy from an abundant natural energy source, in the form of the sarcocarp harvested from coconuts. This component is mostly discarded as waste. However, through its usage as a feedstock for MFCs to produce useful energy in this study, the sarcocarp can be utilized meaningfully. The monospecies S. oneidensis system was able to generate bioenergy in a short experimental time frame while the monospecies E. coli system generated significantly less bioenergy. A combination of E. coli and S. oneidensis in the ratio of 1:9 (v:v) significantly enhanced the experimental time frame and magnitude of bioenergy generation. The synergistic effect is suggested to arise from E. coli and S. oneidensis utilizing different nutrients as electron donors and effect of flavins secreted by S. oneidensis. Confocal images confirmed the presence of biofilms and point towards their importance in generating bioenergy in MFCs.

  10. Degradation of atrazine by microbial consortium in an anaerobic submerged biological filter.

    Science.gov (United States)

    Nasseri, Simin; Baghapour, Mohammad Ali; Derakhshan, Zahra; Faramarzian, Mohammad

    2014-09-01

    Atrazine (2-chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine) (ATZ) is one of the components of S-triazine. Due to its certain characteristics, ATZ causes pollution in various ecosystems and has been of concern for its probable carcinogenic effects on humans. Researchers have used chemical and physical methods for removing ATZ from the environment. Although these methods are quick, they have not been capable of complete mineralization. Therefore, researchers are looking for methods with lower energy consumption and cost and higher efficiency. In this study, biodegradation of ATZ by microbial consortium was evaluated in the aquatic environment. The present study aimed to evaluate the efficiency of ATZ removal from aqueous environments by using an anaerobic submerged biological filter in four concentration levels of atrazine and three hydraulic retention times. The maximum efficiencies of ATZ and soluble chemical oxygen demand (SCOD) were 51.1 and 45.6%, respectively. There was no accumulation of ATZ in the biofilm and the loss of ATZ in the control reactor was negligible. This shows that ATZ removal in this system was due to biodegradation. Furthermore, the results of modeling showed that the Stover-Kincannon model had desirable fitness (R² > 99%) in loading ATZ in this biofilter.

  11. Radio Searches of Fermi LAT Sources and Blind Search Pulsars: The Fermi Pulsar Search Consortium

    CERN Document Server

    Ray, P S; Parent, D; Bhattacharya, D; Bhattacharyya, B; Camilo, F; Cognard, I; Theureau, G; Ferrara, E C; Harding, A K; Thompson, D J; Freire, P C C; Guillemot, L; Gupta, Y; Roy, J; Hessels, J W T; Johnston, S; Keith, M; Shannon, R; Kerr, M; Michelson, P F; Romani, R W; Kramer, M; McLaughlin, M A; Ransom, S M; Roberts, M S E; Parkinson, P M Saz; Ziegler, M; Smith, D A; Stappers, B W; Weltevrede, P; Wood, K S

    2012-01-01

    We present a summary of the Fermi Pulsar Search Consortium (PSC), an international collaboration of radio astronomers and members of the Large Area Telescope (LAT) collaboration, whose goal is to organize radio follow-up observations of Fermi pulsars and pulsar candidates among the LAT gamma-ray source population. The PSC includes pulsar observers with expertise using the world's largest radio telescopes that together cover the full sky. We have performed very deep observations of all 35 pulsars discovered in blind frequency searches of the LAT data, resulting in the discovery of radio pulsations from four of them. We have also searched over 300 LAT gamma-ray sources that do not have strong associations with known gamma-ray emitting source classes and have pulsar-like spectra and variability characteristics. These searches have led to the discovery of a total of 43 new radio millisecond pulsars (MSPs) and four normal pulsars. These discoveries greatly increase the known population of MSPs in the Galactic disk...

  12. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

    Science.gov (United States)

    Joubert, Bonnie R; Felix, Janine F; Yousefi, Paul; Bakulski, Kelly M; Just, Allan C; Breton, Carrie; Reese, Sarah E; Markunas, Christina A; Richmond, Rebecca C; Xu, Cheng-Jian; Küpers, Leanne K; Oh, Sam S; Hoyo, Cathrine; Gruzieva, Olena; Söderhäll, Cilla; Salas, Lucas A; Baïz, Nour; Zhang, Hongmei; Lepeule, Johanna; Ruiz, Carlos; Ligthart, Symen; Wang, Tianyuan; Taylor, Jack A; Duijts, Liesbeth; Sharp, Gemma C; Jankipersadsing, Soesma A; Nilsen, Roy M; Vaez, Ahmad; Fallin, M Daniele; Hu, Donglei; Litonjua, Augusto A; Fuemmeler, Bernard F; Huen, Karen; Kere, Juha; Kull, Inger; Munthe-Kaas, Monica Cheng; Gehring, Ulrike; Bustamante, Mariona; Saurel-Coubizolles, Marie José; Quraishi, Bilal M; Ren, Jie; Tost, Jörg; Gonzalez, Juan R; Peters, Marjolein J; Håberg, Siri E; Xu, Zongli; van Meurs, Joyce B; Gaunt, Tom R; Kerkhof, Marjan; Corpeleijn, Eva; Feinberg, Andrew P; Eng, Celeste; Baccarelli, Andrea A; Benjamin Neelon, Sara E; Bradman, Asa; Merid, Simon Kebede; Bergström, Anna; Herceg, Zdenko; Hernandez-Vargas, Hector; Brunekreef, Bert; Pinart, Mariona; Heude, Barbara; Ewart, Susan; Yao, Jin; Lemonnier, Nathanaël; Franco, Oscar H; Wu, Michael C; Hofman, Albert; McArdle, Wendy; Van der Vlies, Pieter; Falahi, Fahimeh; Gillman, Matthew W; Barcellos, Lisa F; Kumar, Ashish; Wickman, Magnus; Guerra, Stefano; Charles, Marie-Aline; Holloway, John; Auffray, Charles; Tiemeier, Henning W; Smith, George Davey; Postma, Dirkje; Hivert, Marie-France; Eskenazi, Brenda; Vrijheid, Martine; Arshad, Hasan; Antó, Josep M; Dehghan, Abbas; Karmaus, Wilfried; Annesi-Maesano, Isabella; Sunyer, Jordi; Ghantous, Akram; Pershagen, Göran; Holland, Nina; Murphy, Susan K; DeMeo, Dawn L; Burchard, Esteban G; Ladd-Acosta, Christine; Snieder, Harold; Nystad, Wenche; Koppelman, Gerard H; Relton, Caroline L; Jaddoe, Vincent W V; Wilcox, Allen; Melén, Erik; London, Stephanie J

    2016-04-01

    Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy remains an important public health problem that impacts child health in a myriad of ways and has potential lifelong consequences. The mechanisms are largely unknown, but epigenetics most likely plays a role. We formed the Pregnancy And Childhood Epigenetics (PACE) consortium and meta-analyzed, across 13 cohorts (n = 6,685), the association between maternal smoking in pregnancy and newborn blood DNA methylation at over 450,000 CpG sites (CpGs) by using the Illumina 450K BeadChip. Over 6,000 CpGs were differentially methylated in relation to maternal smoking at genome-wide statistical significance (false discovery rate, 5%), including 2,965 CpGs corresponding to 2,017 genes not previously related to smoking and methylation in either newborns or adults. Several genes are relevant to diseases that can be caused by maternal smoking (e.g., orofacial clefts and asthma) or adult smoking (e.g., certain cancers). A number of differentially methylated CpGs were associated with gene expression. We observed enrichment in pathways and processes critical to development. In older children (5 cohorts, n = 3,187), 100% of CpGs gave at least nominal levels of significance, far more than expected by chance (p value smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure.

  13. Biodegradation of petroleum sludge and petroleum polluted soil by a bacterial consortium: a laboratory study.

    Science.gov (United States)

    Gojgic-Cvijovic, G D; Milic, J S; Solevic, T M; Beskoski, V P; Ilic, M V; Djokic, L S; Narancic, T M; Vrvic, M M

    2012-02-01

    This article presents a study of the efficiency and degradation pattern of samples of petroleum sludge and polluted sandy soil from an oil refinery. A bacterial consortium, consisting of strains from the genera Pseudomonas, Achromobacter, Bacillus and Micromonospora, was isolated from a petroleum sludge sample and characterized. The addition of nitrogen and phosphorus nutrients and a chemical surfactant to both the samples and bioaugmentation to the soil sample were applied under laboratory conditions. The extent of biodegradation was monitored by the gravimetric method and analysis of the residual oil by gas chromatography. Over a 12-week experiment, the achieved degree of TPH (total petroleum hydrocarbon) degradation amounted to 82-88% in the petroleum sludge and 86-91% in the polluted soil. Gas chromatography-mass spectrometry was utilized to determine the biodegradability and degradation rates of n-alkanes, isoprenoids, steranes, diasteranes and terpanes. Complete degradation of the n-alkanes and isoprenoids fractions occurred in both the samples. In addition, the intensities of the peaks corresponding to tricyclic terpenes and homohopanes were decreased, while significant changes were also observed in the distribution of diasteranes and steranes.

  14. Industrial Consortium for the Utilization of the Geopressured-Geothermal Resource. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    Negus-deWys, J. (ed.)

    1990-03-01

    The Geopressured-Geothermal Program, now in its fifteenth year, is entering the transition period to commercial use. The industry cost-shared proposals to the consortium, represented in the presentations included in these proceedings, attest to the interest developing in the industrial community in utilizing the geopressured-geothermal resource. Sixty-five participants attended these sessions, two-thirds of whom represented industry. The areas represented by cost-shared proposals include (1) thermal enhanced oil recovery, (2) direct process use of thermal energy, e.g., aquaculture and agriculture, (3) conversion of thermal energy to electricity, (4) environment related technologies, e.g., use of supercritical processes, and (5) operational proposals, e.g., a field manual for scale inhibitors. It is hoped that from this array of potential use projects, some will persist and be successful in proving the viability of using the geopressured-geothermal resource. Such industrial use of an alternative and relatively clean energy resource will benefit our nation and its people.

  15. Overview of the Consortium for the Advanced Simulation of Light Water Reactors (CASL

    Directory of Open Access Journals (Sweden)

    Kulesza Joel A.

    2016-01-01

    Full Text Available The Consortium for Advanced Simulation of Light Water Reactors (CASL was established in July 2010 for the purpose of providing advanced modeling and simulation solutions for commercial nuclear reactors. The primary goal is to provide coupled, higher-fidelity, usable modeling and simulation capabilities than are currently available. These are needed to address light water reactor (LWR operational and safety performance-defining phenomena that are not yet able to be fully modeled taking a first-principles approach. In order to pursue these goals, CASL has participation from laboratory, academic, and industry partners. These partners are pursuing the solution of ten major “Challenge Problems” in order to advance the state-of-the-art in reactor design and analysis to permit power uprates, higher burnup, life extension, and increased safety. At present, the problems being addressed by CASL are primarily reactor physics-oriented; however, this paper is intended to introduce CASL to the reactor dosimetry community because of the importance of reactor physics modelling and nuclear data to define the source term for that community and the applicability and extensibility of the transport methods being developed.

  16. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.

    Science.gov (United States)

    Gaudet, Pascale; Livstone, Michael S; Lewis, Suzanna E; Thomas, Paul D

    2011-09-01

    The goal of the Gene Ontology (GO) project is to provide a uniform way to describe the functions of gene products from organisms across all kingdoms of life and thereby enable analysis of genomic data. Protein annotations are either based on experiments or predicted from protein sequences. Since most sequences have not been experimentally characterized, most available annotations need to be based on predictions. To make as accurate inferences as possible, the GO Consortium's Reference Genome Project is using an explicit evolutionary framework to infer annotations of proteins from a broad set of genomes from experimental annotations in a semi-automated manner. Most components in the pipeline, such as selection of sequences, building multiple sequence alignments and phylogenetic trees, retrieving experimental annotations and depositing inferred annotations, are fully automated. However, the most crucial step in our pipeline relies on software-assisted curation by an expert biologist. This curation tool, Phylogenetic Annotation and INference Tool (PAINT) helps curators to infer annotations among members of a protein family. PAINT allows curators to make precise assertions as to when functions were gained and lost during evolution and record the evidence (e.g. experimentally supported GO annotations and phylogenetic information including orthology) for those assertions. In this article, we describe how we use PAINT to infer protein function in a phylogenetic context with emphasis on its strengths, limitations and guidelines. We also discuss specific examples showing how PAINT annotations compare with those generated by other highly used homology-based methods. PMID:21873635

  17. Overview of the Consortium for the Advanced Simulation of Light Water Reactors (CASL)

    Science.gov (United States)

    Kulesza, Joel A.; Franceschini, Fausto; Evans, Thomas M.; Gehin, Jess C.

    2016-02-01

    The Consortium for Advanced Simulation of Light Water Reactors (CASL) was established in July 2010 for the purpose of providing advanced modeling and simulation solutions for commercial nuclear reactors. The primary goal is to provide coupled, higher-fidelity, usable modeling and simulation capabilities than are currently available. These are needed to address light water reactor (LWR) operational and safety performance-defining phenomena that are not yet able to be fully modeled taking a first-principles approach. In order to pursue these goals, CASL has participation from laboratory, academic, and industry partners. These partners are pursuing the solution of ten major "Challenge Problems" in order to advance the state-of-the-art in reactor design and analysis to permit power uprates, higher burnup, life extension, and increased safety. At present, the problems being addressed by CASL are primarily reactor physics-oriented; however, this paper is intended to introduce CASL to the reactor dosimetry community because of the importance of reactor physics modelling and nuclear data to define the source term for that community and the applicability and extensibility of the transport methods being developed.

  18. Clinical practice of image-guided spine radiosurgery - results from an international research consortium

    International Nuclear Information System (INIS)

    Spinal radiosurgery is a quickly evolving technique in the radiotherapy and neurosurgical communities. However, the methods of spine radiosurgery have not been standardized. This article describes the results of a survey about the methods of spine radiosurgery at five international institutions. All institutions are members of the Elekta Spine Radiosurgery Research Consortium and have a dedicated research and clinical focus on image-guided radiosurgery. The questionnaire consisted of 75 items covering all major steps of spine radiosurgery. Strong agreement in the methods of spine radiosurgery was observed. In particular, similarities were observed with safety and quality assurance playing an important role in the methods of all institutions, cooperation between neurosurgeons and radiation oncologists in case selection, dedicated imaging for target- and organ-at-risk delineation, application of proper safety margins for the target volume and organs-at-risk, conformal planning and precise image-guided treatment delivery, and close clinical and radiological follow-up. In contrast, three major areas of uncertainty and disagreement were identified: 1) Indications and contra-indications for spine radiosurgery; 2) treatment dose and fractionation and 3) tolerance dose of the spinal cord. Results of this study reflect the current practice of spine radiosurgery in large academic centers. Despite close agreement was observed in many steps of spine radiosurgery, further research in form of retrospective and especially prospective studies is required to refine the details of spinal radiosurgery in terms of safety and efficacy

  19. Validation of the Saskatoon Falls Prevention Consortium's Falls Screening and Referral Algorithm

    Science.gov (United States)

    Lawson, Sara Nicole; Zaluski, Neal; Petrie, Amanda; Arnold, Cathy; Basran, Jenny

    2013-01-01

    ABSTRACT Purpose: To investigate the concurrent validity of the Saskatoon Falls Prevention Consortium's Falls Screening and Referral Algorithm (FSRA). Method: A total of 29 older adults (mean age 77.7 [SD 4.0] y) residing in an independent-living senior's complex who met inclusion criteria completed a demographic questionnaire and the components of the FSRA and Berg Balance Scale (BBS). The FSRA consists of the Elderly Fall Screening Test (EFST) and the Multi-factor Falls Questionnaire (MFQ); it is designed to categorize individuals into low, moderate, or high fall-risk categories to determine appropriate management pathways. A predictive model for probability of fall risk, based on previous research, was used to determine concurrent validity of the FSRI. Results: The FSRA placed 79% of participants into the low-risk category, whereas the predictive model found the probability of fall risk to range from 0.04 to 0.74, with a mean of 0.35 (SD 0.25). No statistically significant correlation was found between the FSRA and the predictive model for probability of fall risk (Spearman's ρ=0.35, p=0.06). Conclusion: The FSRA lacks concurrent validity relative to to a previously established model of fall risk and appears to over-categorize individuals into the low-risk group. Further research on the FSRA as an adequate tool to screen community-dwelling older adults for fall risk is recommended. PMID:24381379

  20. A novel sponge disease caused by a consortium of micro-organisms

    Science.gov (United States)

    Sweet, Michael; Bulling, Mark; Cerrano, Carlo

    2015-09-01

    In healthy sponges, microbes have been shown to account for up to 40 % of tissues. The majority of these are thought to originate from survivors evading digestion and immune responses of the sponge and growing and residing in the microenvironments of the mesophyll. Although a large percentage of these microbes are likely commensals, they may also include potentially pathogenic agents, which under specific conditions, such as temperature stress, may cause disease. Here we report a novel disease (sponge necrosis syndrome) that is severely affecting populations of the sponge Callyspongia ( Euplacella) aff biru. Both ITS fungal and 16S rDNA bacterial diversities were assessed in healthy and diseased individuals, highlighting six potential primary causal agents for this new disease: two bacteria, a Rhodobacteraceae sp. and a cyanobacterium, Hormoscilla spongeliae (formally identified as Oscillatoria spongeliae), and four fungi, a Ascomycota sp., a Pleosporales sp., a Rhabdocline sp., and a Clasosporium sp. Furthermore, histological analysis showed the dominance of fungal hyphae rather than bacteria throughout the disease lesion, which was absent or rare in healthy tissues. Inoculation trails showed that only a combination of one bacterium and one fungus could replicate the disease, fulfilling Henle-Koch's postulates and showing that this sponge disease is caused by a poly-microbial consortium.

  1. Isolation and characterization of two novel halotolerant Catechol 2, 3-dioxygenases from a halophilic bacterial consortium

    Science.gov (United States)

    Guo, Guang; Fang, Tingting; Wang, Chongyang; Huang, Yong; Tian, Fang; Cui, Qijia; Wang, Hui

    2015-12-01

    Study of enzymes in halophiles will help to understand the mechanism of aromatic hydrocarbons degradation in saline environment. In this study, two novel catechol 2,3-dioxygenases (C23O1 and C23O2) were cloned and overexpressed from a halophilic bacterial consortium enriched from an oil-contaminated saline soil. Phylogenetic analysis indicated that the novel C23Os and their relatives formed a new branch in subfamily I.2.A of extradiol dioxygenases and the sequence differences were further analyzed by amino acid sequence alignment. Two enzymes with the halotolerant feature were active over a range of 0-30% salinity and they performed more stable at high salinity than in the absence of salt. Surface electrostatic potential and amino acids composition calculation suggested high acidic residues content, accounting for their tolerance to high salinity. Moreover, two enzymes were further characterized. The enzymes activity both increased in the presence of Fe3+, Fe2+, Cu2+ and Al3+ and showed no significant inhibition by other tested metal ions. The optimal temperatures for the C23Os were 40 °C and 60 °C and their best substrates were catechol and 4-methylcatechol respectively. As the firstly isolated and characterized catechol dioxygenases from halophiles, the two halotolerant C23Os presented novel characteristics suggesting their potential application in aromatic hydrocarbons biodegradation.

  2. Coordinating centers in cancer epidemiology research: the Asia Cohort Consortium coordinating center.

    Science.gov (United States)

    Rolland, Betsy; Smith, Briana R; Potter, John D

    2011-10-01

    Although it is tacitly recognized that a good coordinating center (CC) is essential to the success of any multisite collaborative project, very little study has been done on what makes a CC successful, why some CCs fail, or how to build a CC that meets the needs of a given project. Moreover, very little published guidance is available, as few CCs outside the clinical trial realm write about their work. The Asia Cohort Consortium (ACC) is a collaborative cancer epidemiology research project that has made strong scientific and organizational progress over the past 3 years by focusing its CC on the following activities: collaboration development; operations management; statistical and data management; and communications infrastructure and tool development. Our hope is that, by sharing our experience building the ACC CC, we can begin a conversation about what it means to run a CC for multi-institutional collaboration in cancer epidemiology, help other collaborative projects solve some of the issues associated with collaborative research, and learn from others. PMID:21803842

  3. Improving the quality of geriatric nursing care: enduring outcomes from the geriatric nursing education consortium.

    Science.gov (United States)

    Gray-Miceli, Deanna; Wilson, Laurie Dodge; Stanley, Joan; Watman, Rachael; Shire, Amy; Sofaer, Shoshanna; Mezey, Mathy

    2014-01-01

    The nation's aging demography, few nursing faculty with gerontological nursing expertise, and insufficient geriatric content in nursing programs have created a national imperative to increase the supply of nurses qualified to provide care for older adults. Geriatric Nursing Education Consortium (GNEC), a collaborative program of the John A. Hartford Foundation, the American Association of Colleges of Nursing, and the New York University (NYU) Nursing Hartford Institute for Geriatric Nursing, was initiated to provide faculty with the necessary skills, knowledge, and competency to implement sustainable curricular innovations in care of older adults. This article describes the background, step-by-step process approach to the development of GNEC evidence-based curricular materials, and the dissemination of these materials through 6-, 2-, and a half-day national Faculty Development Institutes (FDIs). Eight hundred eight faculty, representing 418 schools of nursing, attended. A total of 479 individuals responded to an evaluation conducted by Baruch College that showed faculty feasibility to incorporate GNEC content into courses, confidence in teaching and incorporating content, and overall high rating of the GNEC materials. The impact of GNEC is discussed along with effects on faculty participants over 2 years. Administrative- and faculty-level recommendations to sustain and expand GNEC are highlighted. PMID:25455325

  4. From the primary care organizations consortium's proposal to the Interdisciplinary Generalist Curriculum Project.

    Science.gov (United States)

    Bazell, C; Kahn, R

    2001-04-01

    The Interdisciplinary Generalist Curriculum (IGC) Project was one element of an overall federal government strategy designed to promote primary care education. This project, undertaken by the Division of Medicine and Dentistry (DMD), Bureau of Health Professions, Health Resources and Services Administration, U.S. Department of Health and Human Services, was the first large-scale medical education contract initiated by DMD. The IGC Project was based on a model proposed by the Primary Care Organizations Consortium (PCOC). The PCOC thesis was that "if students are to decide to pursue a generalist career they must have the opportunity to be taught by generalists." The PCOC Program required an explicit curriculum focusing on generalist knowledge and skills with an emphasis on technology, in the context of education that required training in ambulatory office-based settings. The PCOC Program specified that responsibility for the program's planning, implementation, and evaluation be shared by the three generalist physician faculties of family medicine, general internal medicine, and general pediatrics. In implementation of this demonstration project in ten medical schools across the nation, several lessons have been learned relative to enhancement of generalist education. Among these lessons is that seed money targeted to initiate modest change can act as a catalyst and improve the knowledge and skills afforded medical students concerning generalist practice. Limited funds provided over a sufficient period of time can induce schools to undertake significant curricular change. PMID:11299165

  5. Integrating economic evaluation methods into clinical and translational science award consortium comparative effectiveness educational goals.

    Science.gov (United States)

    Iribarne, Alexander; Easterwood, Rachel; Russo, Mark J; Wang, Y Claire

    2011-06-01

    With the ongoing debate over health care reform in the United States, public health and policy makers have paid growing attention to the need for comparative effectiveness research (CER). Recent allocation of federal funds for CER represents a significant move toward increased evidence-based practice and better-informed allocation of constrained health care resources; however, there is also heated debate on how, or whether, CER may contribute to controlling national health care expenditures. Economic evaluation, in the form of cost-effectiveness or cost-benefit analysis, is often an aspect of CER studies, yet there are no recommendations or guidelines for providing clinical investigators with the necessary skills to collect, analyze, and interpret economic data from clinical trials or observational studies. With an emphasis on multidisciplinary research, the Clinical and Translational Science Award (CTSA) consortium and institutional CTSA sites serve as an important resource for training researchers to engage in CER. In this article, the authors discuss the potential role of CTSA sites in integrating economic evaluation methods into their comparative effectiveness education goals, using the Columbia University Medical Center CTSA as an example. By allowing current and future generations of clinical investigators to become fully engaged not only in CER but also in the economic evaluations that result from such analyses, CTSA sites can help develop the necessary foundation for advancing research to guide clinical decision making and efficient use of limited resources.

  6. Bioleaching of multiple heavy metals from contaminated sediment by mesophile consortium.

    Science.gov (United States)

    Gan, Min; Zhou, Shuang; Li, Mingming; Zhu, Jianyu; Liu, Xinxing; Chai, Liyuan

    2015-04-01

    A defined mesophile consortium including Acidithiobacillus ferrooxidans, Acidithiobacillus thiooxidans, and Leptospirilum ferriphilum was applied in bioleaching sediments contaminated with multiple heavy metals. Flask experiments showed that sulfur favored the acidification in the early stage while pyrite led to a great acidification potential in the later stage. An equal sulfur/pyrite ratio got the best acidification effect. Substrate utilization started with sulfur in the early stage, and then the pH decline and the community shift give rise to the utilization of pyrite. Solubilization efficiency of Zn, Cu, Mn, and Cd reached 96.1, 93.3, 92.13, and 87.65%, respectively. Bioleaching efficiency of other elements (As, Hg, Pb) was not more than 30%. Heavy metal solubilization was highly negatively correlated with pH variation. Logistic models were well fitted with the solubilization efficiency, which can be used to predict the bioleaching process. The dominant species in the early stage of bioleaching were A. ferrooxidans and A. thiooxidans, and the abundance of L. ferriphilum increased together with pyrite utilization and pH decline. PMID:25384695

  7. International Cancer Genome Consortium Data Portal--a one-stop shop for cancer genomics data.

    Science.gov (United States)

    Zhang, Junjun; Baran, Joachim; Cros, A; Guberman, Jonathan M; Haider, Syed; Hsu, Jack; Liang, Yong; Rivkin, Elena; Wang, Jianxin; Whitty, Brett; Wong-Erasmus, Marie; Yao, Long; Kasprzyk, Arek

    2011-01-01

    The International Cancer Genome Consortium (ICGC) is a collaborative effort to characterize genomic abnormalities in 50 different cancer types. To make this data available, the ICGC has created the ICGC Data Portal. Powered by the BioMart software, the Data Portal allows each ICGC member institution to manage and maintain its own databases locally, while seamlessly presenting all the data in a single access point for users. The Data Portal currently contains data from 24 cancer projects, including ICGC, The Cancer Genome Atlas (TCGA), Johns Hopkins University, and the Tumor Sequencing Project. It consists of 3478 genomes and 13 cancer types and subtypes. Available open access data types include simple somatic mutations, copy number alterations, structural rearrangements, gene expression, microRNAs, DNA methylation and exon junctions. Additionally, simple germline variations are available as controlled access data. The Data Portal uses a web-based graphical user interface (GUI) to offer researchers multiple ways to quickly and easily search and analyze the available data. The web interface can assist in constructing complicated queries across multiple data sets. Several application programming interfaces are also available for programmatic access. Here we describe the organization, functionality, and capabilities of the ICGC Data Portal. PMID:21930502

  8. Evaluation of whey fermented by Enterococcus faecium in consortium with Veilonella parvula in ruminant feeding

    Directory of Open Access Journals (Sweden)

    Juliana Silva de Oliveira

    2012-01-01

    Full Text Available The objective of this study was to evaluate the whey fermented by Enterococcus faecium in consortium with Veilonella parvula on the in vitro growth of ruminal bacteria and as a supplement in the cattle diet. In the in vitro experiment, a randomized design, with the following combinations was used: ruminal bacteria; ruminal bacteria and inactive whey; ruminal bacteria and active whey; and active whey. In the in vivo experiment, five fistulated Zebu Holstein-Zebu crossbred heifers were distributed in a 5 × 5 Latin square. Supplements were formulated without the addition of whey, with the addition of two levels of unfermented whey (2.5 and 5 L/day or two levels of fermented whey (2.5 and 5 L/day. A positive effect of the whey fermentation was detected on the consumption of dry matter, organic matter, crude protein, ether extract, non-fiber carbohydrates and neutral detergent fiber, corrected for ash and protein in kg/day. No effects of whey were observed on the pH and concentration of rumen ammonia nitrogen, serum concentration of urea and glucose, urinary excretion of urea or nutrient digestibility, except for the total digestible nutrients. Supplementation with whey improved the apparent nitrogen balance, but supplementation with fermented whey decreased the intestinal flow of microbial nitrogen and microbial synthesis efficiency in relation to the unfermented whey. The whey fermentation process does not optimize the physiological responses of heifers supplemented with 2.5 and 5.0 L of whey.

  9. Integrated Genomic Analysis of Diverse Induced Pluripotent Stem Cells from the Progenitor Cell Biology Consortium.

    Science.gov (United States)

    Salomonis, Nathan; Dexheimer, Phillip J; Omberg, Larsson; Schroll, Robin; Bush, Stacy; Huo, Jeffrey; Schriml, Lynn; Ho Sui, Shannan; Keddache, Mehdi; Mayhew, Christopher; Shanmukhappa, Shiva Kumar; Wells, James; Daily, Kenneth; Hubler, Shane; Wang, Yuliang; Zambidis, Elias; Margolin, Adam; Hide, Winston; Hatzopoulos, Antonis K; Malik, Punam; Cancelas, Jose A; Aronow, Bruce J; Lutzko, Carolyn

    2016-07-12

    The rigorous characterization of distinct induced pluripotent stem cells (iPSC) derived from multiple reprogramming technologies, somatic sources, and donors is required to understand potential sources of variability and downstream potential. To achieve this goal, the Progenitor Cell Biology Consortium performed comprehensive experimental and genomic analyses of 58 iPSC from ten laboratories generated using a variety of reprogramming genes, vectors, and cells. Associated global molecular characterization studies identified functionally informative correlations in gene expression, DNA methylation, and/or copy-number variation among key developmental and oncogenic regulators as a result of donor, sex, line stability, reprogramming technology, and cell of origin. Furthermore, X-chromosome inactivation in PSC produced highly correlated differences in teratoma-lineage staining and regulator expression upon differentiation. All experimental results, and raw, processed, and metadata from these analyses, including powerful tools, are interactively accessible from a new online portal at https://www.synapse.org to serve as a reusable resource for the stem cell community. PMID:27293150

  10. Strategic planning by the palliative care steering committee of the Middle East Cancer Consortium.

    Science.gov (United States)

    Moore, Shannon Y; Pirrello, Rosene D; Christianson, Sonya K; Ferris, Frank D

    2011-04-01

    High quality comprehensive palliative care is a critical need for millions of patients and families, but remains only a dream in many parts of the world. The failure to do a strategic planning process is one obstacle to advancing education and pain prevention and relief. The Middle Eastern Cancer Consortium Steering Committee attendees completed an initial strategic planning process and identified "developmental steps" to advance palliative care. Underscoring the multi-disciplinary nature of comprehensive palliative care, discipline-specific planning was done (adult and pediatric cancer and medicine, pharmacy, nursing) in a separate process from country-specific planning. Delineating the layers of intersection and differences between disciplines and countries was very powerful. Finding the common strengths and weaknesses in the status quo creates the potential for a more powerful regional response to the palliative care needs. Implementing and refining these preliminary strategic plans will augment and align the efforts to advance palliative care education and pain management in the Middle East. The dream to prevent and relieve suffering for millions of patients with advanced disease will become reality with a powerful strategic planning process well implemented.

  11. Parental Tobacco Smoking and Acute Myeloid Leukemia: The Childhood Leukemia International Consortium.

    Science.gov (United States)

    Metayer, Catherine; Petridou, Eleni; Aranguré, Juan Manuel Mejía; Roman, Eve; Schüz, Joachim; Magnani, Corrado; Mora, Ana Maria; Mueller, Beth A; de Oliveira, Maria S Pombo; Dockerty, John D; McCauley, Kathryn; Lightfoot, Tracy; Hatzipantelis, Emmanouel; Rudant, Jérémie; Flores-Lujano, Janet; Kaatsch, Peter; Miligi, Lucia; Wesseling, Catharina; Doody, David R; Moschovi, Maria; Orsi, Laurent; Mattioli, Stefano; Selvin, Steve; Kang, Alice Y; Clavel, Jacqueline

    2016-08-15

    The association between tobacco smoke and acute myeloid leukemia (AML) is well established in adults but not in children. Individual-level data on parental cigarette smoking were obtained from 12 case-control studies from the Childhood Leukemia International Consortium (CLIC, 1974-2012), including 1,330 AML cases diagnosed at age controls. We conducted pooled analyses of CLIC studies, as well as meta-analyses of CLIC and non-CLIC studies. Overall, maternal smoking before, during, or after pregnancy was not associated with childhood AML; there was a suggestion, however, that smoking during pregnancy was associated with an increased risk in Hispanics (odds ratio = 2.08, 95% confidence interval (CI): 1.20, 3.61) but not in other ethnic groups. By contrast, the odds ratios for paternal lifetime smoking were 1.34 (95% CI: 1.11, 1.62) and 1.18 (95% CI: 0.92, 1.51) in pooled and meta-analyses, respectively. Overall, increased risks from 1.2- to 1.3-fold were observed for pre- and postnatal smoking (P < 0.05), with higher risks reported for heavy smokers. Associations with paternal smoking varied by histological type. Our analyses suggest an association between paternal smoking and childhood AML. The association with maternal smoking appears limited to Hispanic children, raising questions about ethnic differences in tobacco-related exposures and biological mechanisms, as well as study-specific biases. PMID:27492895

  12. Enhancement of biogas production from swine manure by a lignocellulolytic microbial consortium.

    Science.gov (United States)

    Tuesorn, Suchada; Wongwilaiwalin, Sarunyou; Champreda, Verawat; Leethochawalit, Malinee; Nopharatana, Annop; Techkarnjanaruk, Somkiet; Chaiprasert, Pawinee

    2013-09-01

    Anaerobic digestion of lignocellulosic wastes is limited by inefficient hydrolysis of recalcitrant substrates, leading to low biogas yield. In this study, the potential of a lignocellulolytic microbial consortium (LMC) for enhancing biogas production from fibre-rich swine manure (SM) was assessed. Biochemical methane potential assay showed that inoculation of structurally stable LMC to anaerobic digestion led to increase biogas production under mesophilic and thermophilic conditions. The greatest enhancement was observed at 37°C with a LMC/SM ratio of 1.5:1 mg VSS/g VS leading to biogas and methane yields of 355 and 180 ml/g VS(added) respectively, equivalent to 40% and 55% increases compared with the control. The LMC was shown to increase the efficiency of total solid, chemical oxygen demand removal and degradation of cellulose and hemicelluloses (1.87 and 1.65-fold, respectively). The LMC-supplemented process was stable over a 90 d biogas production period. This work demonstrates the potential of LMC for enhancing biogas from lignocellulosic wastes.

  13. Sociodemographic Predictors of Breast Reconstruction Procedure Choice: Analysis of the Mastectomy Reconstruction Outcomes Consortium Study Cohort

    Directory of Open Access Journals (Sweden)

    Tiffany N. S. Ballard

    2015-01-01

    Full Text Available Background. To promote patient-centered care, it is important to understand the impact of sociodemographic factors on procedure choice for women undergoing postmastectomy breast reconstruction. In this context, we analyzed the effects of these variables on the reconstructive method chosen. Methods. Women undergoing postmastectomy breast reconstruction were recruited for the prospective Mastectomy Reconstruction Outcomes Consortium Study. Procedure types were divided into tissue expander-implant/direct-to-implant and abdominally based flap reconstructions. Adjusted odds ratios were calculated from logistic regression. Results. The analysis included 2,203 women with current or previous breast cancer and 202 women undergoing prophylactic mastectomy. Compared with women <40 years old with current or previous breast cancer, those 40 to 59 were significantly more likely to undergo an abdominally based flap. Women working or attending school full-time were more likely to receive an autologous procedure than those working part-time or volunteering. Women undergoing prophylactic mastectomy who were ≥50 years were more likely to undergo an abdominal flap compared to those <40. Conclusions. Our results indicate that sociodemographic factors affect the reconstructive procedure received. As we move forward into a new era of patient-centered care, providing tailored treatment options to reconstruction patients will likely lead to higher satisfaction and better outcomes for those we serve.

  14. Benchmarks for interface-tracking codes in the consortium for advanced simulation of LWRs (CASL)

    International Nuclear Information System (INIS)

    A major innovation pursued by the Consortium for Advanced Simulation of LWRs (CASL) is the use of Interface Tracking Methods (ITM) to generate high-fidelity closure relations for two-phase flow and heat transfer phenomena (e.g. nucleate boiling, bubble break-up and coalescence, vapor condensation, etc.), to be used in coarser CFD, subchannel and system codes. ITMs do not assume an idealized geometry of the interface between the liquid and vapor phases, but rather calculate it from ‘first principles’. Also, used within the context of high-fidelity turbulence simulations, such as Direct Numerical Simulation (DNS) or Large Eddy Simulation (LES), ITMs can resolve the velocity (including the fluctuating field) and temperature/scalar gradients near the liquid-vapor interface, so prediction of the exchange of momentum, mass and heat at the interface in principle requires no empirical correlations. The physical complexity of the two-phase flow and heat transfer phenomena encountered in LWRs naturally lends itself to an ITM analysis approach. Several codes featuring ITM capabilities are available within CASL. These are TransAT, STAR-CCM+, PHASTA, FTC3D and FELBM. They use a variety of ITMs ranging from Volume-Of- Fluid to Level-Set, from Front-Tracking to Lattice-Boltzmann. A series of benchmark simulations is being developed to test the key capabilities of these codes and their ITMs. In this paper, three such benchmark simulations, testing DNS, LES and interface tracking, respectively, are briefly described. (author)

  15. Overview of the consortium of hospitals advancing research on tobacco (chart

    Directory of Open Access Journals (Sweden)

    Riley William T

    2012-08-01

    Full Text Available Abstract Background The Consortium of Hospitals Advancing Research on Tobacco (CHART is a network of six projects and a research coordinating unit funded by the National Heart, Lung, and Blood Institute, the National Cancer Institute, the National Institute on Drug Abuse, and the National Institutes of Health (NIH Office of Behavioral and Social Science Research. The CHART projects will assess the effectiveness and cost-effectiveness of smoking cessation interventions initiated during hospitalization and continued post-discharge. Methods/design Along with a seventh project funded previously under the NIH Challenge grants, the CHART projects will assess smoking cessation strategies delivered to approximately 10,000 hospitalized smokers across a geographically diverse group of nearly 20 private, public, academic, and community hospitals. The CHART research coordinating unit at Kaiser Permanente Center for Health Research provides organizational and data coordination support, facilitating the development of common measures for combining data from multiple CHART projects. Discussion The targeted enrollment in CHART, if achieved, will represent the largest, most diverse pooled dataset of hospitalized smokers receiving smoking cessation assistance, and is designed to contribute to the dissemination and implementation of smoking cessation interventions provided by hospital systems.

  16. Leaving Elsevier's "big deal": an evaluation of the Italian National Institute of Health experience inside the Bibliosan Consortium

    OpenAIRE

    Toni, Franco

    2012-01-01

    In 2011 the Istituto Superiore di Sanità (ISS), the Italian National Institute of Health, has been forced, due to economic reason, to leave the Bibliosan Consortium contract with the publisher Elsevier. The contract, following the “big deal” model, provided for the maintenance of paper subscriptions and the payment of an additional fee for the whole electronic collection (more than 2,000 journal titles). The continuous increase of annual costs has led to unsustainable growth in costs and...

  17. Molecular characterization of a microbial consortium involved in methane oxidation coupled to denitrification under micro-aerobic conditions

    OpenAIRE

    Liu, Jingjing; Sun, Faqian; Wang, Liang; Ju, Xi; Wu, Weixiang; Chen, Yingxu

    2013-01-01

    Methane can be used as an alternative carbon source in biological denitrification because it is nontoxic, widely available and relatively inexpensive. A microbial consortium involved in methane oxidation coupled to denitrification (MOD) was enriched with nitrite and nitrate as electron acceptors under micro-aerobic conditions. The 16S rRNA gene combined with pmoA phylogeny of methanotrophs and nirK phylogeny of denitrifiers were analysed to reveal the dominant microbial populations and functi...

  18. Microbial Corrosion of API 5L X-70 Carbon Steel by ATCC 7757 and Consortium of Sulfate-Reducing Bacteria

    OpenAIRE

    2014-01-01

    Various cases of accidents involving microbiology influenced corrosion (MIC) were reported by the oil and gas industry. Sulfate reducing bacteria (SRB) have always been linked to MIC mechanisms as one of the major causes of localized corrosion problems. In this study, SRB colonies were isolated from the soil in suspected areas near the natural gas transmission pipeline in Malaysia. The effects of ATCC 7757 and consortium of isolated SRB upon corrosion on API 5L X-70 carbon steel coupon were i...

  19. Environmental Dissolved Organic Matter Governs Biofilm Formation and Subsequent Linuron Degradation Activity of a Linuron-Degrading Bacterial Consortium

    Science.gov (United States)

    Horemans, Benjamin; Breugelmans, Philip; Hofkens, Johan; Smolders, Erik

    2013-01-01

    It was examined whether biofilm growth on dissolved organic matter (DOM) of a three-species consortium whose members synergistically degrade the phenylurea herbicide linuron affected the consortium's integrity and subsequent linuron-degrading functionality. Citrate as a model DOM and three environmental DOM (eDOM) formulations of different quality were used. Biofilms developed with all DOM formulations, and the three species were retained in the biofilm. However, biofilm biomass, species composition, architecture, and colocalization of member strains depended on DOM and its biodegradability. To assess the linuron-degrading functionality, biofilms were subsequently irrigated with linuron at 10 mg liter−1 or 100 μg liter−1. Instant linuron degradation, the time needed to attain maximal linuron degradation, and hence the total amount of linuron removed depended on both the DOM used for growth and the linuron concentration. At 10 mg liter−1, the final linuron degradation efficiency was as high as previously observed without DOM except for biofilms fed with humic acids which did not degrade linuron. At 100 μg liter−1 linuron, DOM-grown biofilms degraded linuron less efficiently than biofilms receiving 10 mg liter−1 linuron. The amount of linuron removed was more correlated with biofilm species composition than with biomass or structure. Based on visual observations, colocalization of consortium members in biofilms after the DOM feed appears essential for instant linuron-degrading activity and might explain the differences in overall linuron degradation. The data show that DOM quality determines biofilm structure and composition of the pesticide-degrading consortium in periods with DOM as the main carbon source and can affect subsequent pesticide-degrading activity, especially at micropollutant concentrations. PMID:23666338

  20. The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortium

    OpenAIRE

    van Dam, Teunis JP; Wheway, Gabrielle; Slaats, Gisela G.; Huynen, Martijn A; Giles, Rachel H.

    2013-01-01

    The multinational SYSCILIA consortium aims to gain a mechanistic understanding of the cilium. We utilize multiple parallel high-throughput (HTP) initiatives to develop predictive models of relationships between complex genotypes and variable phenotypes of ciliopathies. The models generated are only as good as the wet laboratory data fed into them. It is therefore essential to orchestrate a well-annotated and high-confidence dataset to be able to assess the quality of any HTP dataset. Here, we...

  1. The National NeuroAIDS Tissue Consortium (NNTC) Database: an integrated database for HIV-related studies

    OpenAIRE

    Cserhati, Matyas F.; Pandey, Sanjit; Beaudoin, James J.; Baccaglini, Lorena; Guda, Chittibabu; Fox, Howard S

    2015-01-01

    We herein present the National NeuroAIDS Tissue Consortium-Data Coordinating Center (NNTC-DCC) database, which is the only available database for neuroAIDS studies that contains data in an integrated, standardized form. This database has been created in conjunction with the NNTC, which provides human tissue and biofluid samples to individual researchers to conduct studies focused on neuroAIDS. The database contains experimental datasets from 1206 subjects for the following categories (which a...

  2. Improving performance in the detection and management of cystic fibrosis-related diabetes in the Mountain West Cystic Fibrosis Consortium

    OpenAIRE

    Theodore G Liou; Jensen, Judith L; Allen, Sarah E; Brayshaw, Sara J.; Brown, Mark A; Chatfield, Barbara; Koenig, Joni; McDonald, Catherine; Packer, Kristyn A; Peet, Kimberly; Radford, Peggy; Reineke, Linda M; Otsuka, Kim; Wagener, Jeffrey S.; Young, David

    2016-01-01

    Objective Cystic fibrosis (CF)-related diabetes (CFRD) is associated with increased morbidity and mortality. Improved detection and management may improve outcomes; however, actual practice falls short of published guidelines. We studied efforts to improve CFRD screening and management in the Mountain West CF Consortium (MWCFC). Research design and methods This is a prospective observational cohort study evaluating quality improvement by accredited CF centers in Arizona, Colorado, New Mexico,...

  3. Novel dark fermentation involving bioaugmentation with constructed bacterial consortium for enhanced biohydrogen production from pretreated sewage sludge

    Energy Technology Data Exchange (ETDEWEB)

    Kotay, Shireen Meher; Das, Debabrata [Department of Biotechnology, Indian Institute of Technology, Kharagpur (India)

    2009-09-15

    The present study summarizes the observations on various nutrient and seed formulation methods using sewage sludge that have been aimed at ameliorating the biohydrogen production potential. Pretreatment methods viz., acid/base treatment, heat treatment, sterilization, freezing-thawing, microwave, ultrasonication and chemical supplementation were attempted on sludge. It was observed that pretreatment was essential not only to reduce the needless, competitive microbial load but also to improve the nutrient solublization of sludge. Heat treatment at 121 C for 20 min was found to be most effective in reducing the microbial load by 98% and hydrolyzing the organic fraction of sludge. However, this pretreatment alone was either not sufficient or inconsistent in developing a suitable microbial consortium for hydrogen production. Hydrogen yield was found to improve 1.5-4 times upon inoculation with H{sub 2}-producing microorganisms. A defined microbial consortium was developed consisting of three established bacteria viz., Enterobacter cloacae IIT-BT 08, Citrobacter freundii IIT-BT L139 and Bacillus coagulans IIT-BT S1. Following pretreatments soluble proteins and lipids (the major component of the sludge) were also found to be consumed besides carbohydrates. This laid out the concurrent proteolytic/lipolytic ability of the developed H{sub 2}-producing consortium. 1:1:1 v/v ratio of these bacteria in consortium was found to give the maximum yield of H{sub 2} from sludge, 39.15 ml H{sub 2}/g COD{sub reduced}. 15%v/v dilution and supplementation with 0.5%w/v cane molasses prior to heat treatment was found to further improve the yield to 41.23 ml H{sub 2}/g COD{sub reduced}. (author)

  4. Induction of Drought Tolerance in Cucumber Plants by a Consortium of Three Plant Growth-Promoting Rhizobacterium Strains

    OpenAIRE

    Chun-Juan Wang; Wei Yang; Chao Wang; Chun Gu; Dong-Dong Niu; Hong-Xia Liu; Yun-Peng Wang; Jian-Hua Guo

    2012-01-01

    Our previous work showed that a consortium of three plant growth-promoting rhizobacterium (PGPR) strains (Bacillus cereus AR156, Bacillus subtilis SM21, and Serratia sp. XY21), termed as BBS for short, was a promising biocontrol agent. The present study investigated its effect on drought tolerance in cucumber plants. After withholding watering for 13 days, BBS-treated cucumber plants had much darker green leaves and substantially lighter wilt symptoms than control plants. Compared to the cont...

  5. ESTABLISHMENT OF AN INDUSTRY-DRIVEN CONSORTIUM FOCUSED ON IMPROVING THE PRODUCTION PERFORMANCE OF DOMESTIC STRIPPER WELLS

    Energy Technology Data Exchange (ETDEWEB)

    Joel L. Morrison

    2002-09-30

    The Pennsylvania State University, under contract to the U.S. Department of Energy (DOE), National Energy Technology Laboratory (NETL), has established a national industry-driven Stripper Well Consortium (SWC) that is focused on improving the production performance of domestic petroleum and/or natural gas stripper wells. The consortium creates a partnership with the U.S. petroleum and natural gas industries and trade associations, state funding agencies, academia, and the National Energy Technology Laboratory. This report serves as the second topical report. The SWC has grown and diversified its membership during its first 24 months of existence. The Consortium is now focused on building strategic alliances with additional industrial, state, and federal entities to expand further the SWC membership base and transfer technologies as they are developed. In addition, the Consortium has successfully worked to attract state support to co-fund SWC projects. Penn State has entered a co-funding arrangement with the New York State Energy Development Authority (NYSERDA) which has provided $200,000 over the last two years to co-fund stripper well production-orientated projects that have relevance to New York state producers. During this reporting period, the Executive Council approved co-funding for 14 projects that have a total project value of $2,116,897. Since its inception, the SWC has approved cofunding for 27 projects that have a total project value of $3,632,109.84. The SWC has provided $2,242,701 in co-funding for these projects and programmatically maintains a cost share of 39%.

  6. 2012-2013 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Hoh River Watershed, Washington (Deliveries 1 and 2)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Watershed Sciences, Inc. (WSI) collected Light Detection and Ranging (LiDAR) data on the Hoh River watershed survey area for the Puget Sound LiDAR Consortium and...

  7. 2001-2002 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Island County and Northeast Jefferson County, Washington

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — TerraPoint surveyed and created this data for the Puget Sound LiDAR Consortium under contract. The area surveyed is approximately 525 square miles and covers all of...

  8. Korean Consortium's preliminary research for enhancing a probabilistic fracture mechanics code, PRO-LOCA

    International Nuclear Information System (INIS)

    The Battelle developed a probabilistic fracture mechanics code called PRO-LOCA, which can be used as a tool for evaluating the pipe break frequency. It is being further developed through the international co-operative research program, PARTRIDGE. KINS, KHNP-CRI, and KEPCO-E&C are participating in the PARTIRDGE program by composing a Korean Consortium. The members of Korean Consortium performed benchmark analyses using the beta version of PRO-LOCA 4.0 to evaluate the effect of variables such as simulation methods, crack features, loading conditions, and inspection models on the failure probabilities. The benchmark analyses showed that the PRO-LOCA can provide a trend consistent with the expected crack growth and pipe failure behavior. Especially, the availability of the stress intensity factor and crack opening displacement for non-idealized through-wall cracks was proven from this study. This new solution for non-idealized through-wall cracks had been developed by the Korean Consortium and it was newly included in PRO-LOCA 4.0. However, further improvement is needed to address the problems such as the instability of adaptive sampling method and the unexpected trend of failure probabilities at the early stage of crack growth

  9. [Determination of sugars, organic acids and alcohols in microbial consortium fermentation broth from cellulose using high performance liquid chromatography].

    Science.gov (United States)

    Jiang, Yan; Fan, Guifang; Du, Ran; Li, Peipei; Jiang, Li

    2015-08-01

    A high performance liquid chromatographic method was established for the determination of metabolites (sugars, organic acids and alcohols) in microbial consortium fermentation broth from cellulose. Sulfate was first added in the samples to precipitate calcium ions in microbial consortium culture medium and lower the pH of the solution to avoid the dissociation of organic acids, then the filtrates were effectively separated using high performance liquid chromatography. Cellobiose, glucose, ethanol, butanol, glycerol, acetic acid and butyric acid were quantitatively analyzed. The detection limits were in the range of 0.10-2.00 mg/L. The linear correlation coefficients were greater than 0.999 6 in the range of 0.020 to 1.000 g/L. The recoveries were in the range of 85.41%-115.60% with the relative standard deviations of 0.22% -4.62% (n = 6). This method is accurate for the quantitative analysis of the alcohols, organic acids and saccharides in microbial consortium fermentation broth from cellulose.

  10. Aerobic De-Epoxydation of Trichothecene Mycotoxins by a Soil Bacterial Consortium Isolated Using In Situ Soil Enrichment

    Science.gov (United States)

    He, Wei-Jie; Yuan, Qing-Song; Zhang, You-Bing; Guo, Mao-Wei; Gong, An-Dong; Zhang, Jing-Bo; Wu, Ai-Bo; Huang, Tao; Qu, Bo; Li, He-Ping; Liao, Yu-Cai

    2016-01-01

    Globally, the trichothecene mycotoxins deoxynivalenol (DON) and nivalenol (NIV) are among the most widely distributed mycotoxins that contaminate small grain cereals. In this study, a bacterial consortium, PGC-3, with de-epoxydation activity was isolated from soil by an in situ soil enrichment method. Screening of 14 soil samples that were sprayed with DON revealed that 4 samples were able to biotransform DON into de-epoxydized DON (dE-DON). Among these, the PGC-3 consortium showed the highest and most stable activity to biotransform DON into dE-DON and NIV into dE-NIV. PGC-3 exhibited de-epoxydation activity at a wide range of pH (5–10) and temperatures (20–37 °C) values under aerobic conditions. Sequential subculturing with a continued exposure to DON substantially reduced the microbial population diversity of this consortium. Analyses of the 16S rDNA sequences indicated that PGC-3 comprised 10 bacterial genera. Among these, one species, Desulfitobacterium, showed a steady increase in relative abundance, from 0.03% to 1.55% (a 52-fold increase), as higher concentrations of DON were used in the subculture media, from 0 to 500 μg/mL. This study establishes the foundation to further develop bioactive agents that can detoxify trichothecene mycotoxins in cereals and enables for the characterization of detoxifying genes and their regulation. PMID:27669304

  11. Aerobic De-Epoxydation of Trichothecene Mycotoxins by a Soil Bacterial Consortium Isolated Using In Situ Soil Enrichment.

    Science.gov (United States)

    He, Wei-Jie; Yuan, Qing-Song; Zhang, You-Bing; Guo, Mao-Wei; Gong, An-Dong; Zhang, Jing-Bo; Wu, Ai-Bo; Huang, Tao; Qu, Bo; Li, He-Ping; Liao, Yu-Cai

    2016-01-01

    Globally, the trichothecene mycotoxins deoxynivalenol (DON) and nivalenol (NIV) are among the most widely distributed mycotoxins that contaminate small grain cereals. In this study, a bacterial consortium, PGC-3, with de-epoxydation activity was isolated from soil by an in situ soil enrichment method. Screening of 14 soil samples that were sprayed with DON revealed that 4 samples were able to biotransform DON into de-epoxydized DON (dE-DON). Among these, the PGC-3 consortium showed the highest and most stable activity to biotransform DON into dE-DON and NIV into dE-NIV. PGC-3 exhibited de-epoxydation activity at a wide range of pH (5-10) and temperatures (20-37 °C) values under aerobic conditions. Sequential subculturing with a continued exposure to DON substantially reduced the microbial population diversity of this consortium. Analyses of the 16S rDNA sequences indicated that PGC-3 comprised 10 bacterial genera. Among these, one species, Desulfitobacterium, showed a steady increase in relative abundance, from 0.03% to 1.55% (a 52-fold increase), as higher concentrations of DON were used in the subculture media, from 0 to 500 μg/mL. This study establishes the foundation to further develop bioactive agents that can detoxify trichothecene mycotoxins in cereals and enables for the characterization of detoxifying genes and their regulation. PMID:27669304

  12. Removal of methyl parathion and tetrachlorvinphos by a bacterial consortium immobilized on tezontle-packed up-flow reactor.

    Science.gov (United States)

    Yáñez-Ocampo, Gustavo; Sánchez-Salinas, Enrique; Ortiz-Hernández, M Laura

    2011-11-01

    A tezontle-packed up-flow reactor (TPUFR) with an immobilized bacterial consortium for biological treatment of methyl-parathion and tetrachlorvinphos was evaluated. These organophosphate pesticides are widely used in Mexico for insect and mite control, respectively. With the aim of developing a tool for pesticide biodegradation, four flow rates (0.936, 1.41, 2.19, and 3.51 l/h) and four hydraulic residence times (0.313, 0.206, 0.133, and 0.083 h) were evaluated in a TPUFR. In the bioreactor, with an operating time of 8 h and a flow of 0.936 l/h, we obtained 75% efficiency in the removal of methyl-parathion and tetrachlorvinphos. Their adsorptions in the volcanic rock were 9% and 6%, respectively. It was demonstrated that the removal of pesticides was due to the biological activity of the immobilized bacterial consortium. We confirmed the decrease in toxicity in the treated effluent from the bioreactor through the application of acute toxicity tests on Eisenia foetida. Immobilization of a bacterial consortium using tezontle as a support is innovative and an economical tool for the treatment of mixtures of organophosphorus pesticide residues. PMID:21533773

  13. Aerobic De-Epoxydation of Trichothecene Mycotoxins by a Soil Bacterial Consortium Isolated Using In Situ Soil Enrichment

    Directory of Open Access Journals (Sweden)

    Wei-Jie He

    2016-09-01

    Full Text Available Globally, the trichothecene mycotoxins deoxynivalenol (DON and nivalenol (NIV are among the most widely distributed mycotoxins that contaminate small grain cereals. In this study, a bacterial consortium, PGC-3, with de-epoxydation activity was isolated from soil by an in situ soil enrichment method. Screening of 14 soil samples that were sprayed with DON revealed that 4 samples were able to biotransform DON into de-epoxydized DON (dE-DON. Among these, the PGC-3 consortium showed the highest and most stable activity to biotransform DON into dE-DON and NIV into dE-NIV. PGC-3 exhibited de-epoxydation activity at a wide range of pH (5–10 and temperatures (20–37 °C values under aerobic conditions. Sequential subculturing with a continued exposure to DON substantially reduced the microbial population diversity of this consortium. Analyses of the 16S rDNA sequences indicated that PGC-3 comprised 10 bacterial genera. Among these, one species, Desulfitobacterium, showed a steady increase in relative abundance, from 0.03% to 1.55% (a 52-fold increase, as higher concentrations of DON were used in the subculture media, from 0 to 500 μg/mL. This study establishes the foundation to further develop bioactive agents that can detoxify trichothecene mycotoxins in cereals and enables for the characterization of detoxifying genes and their regulation.

  14. A Study of Strategic Alliance for Library Consortium%图书馆联盟之战略联盟探究

    Institute of Scientific and Technical Information of China (English)

    叶仕平

    2012-01-01

    文章阐述了图书馆联盟的发展现状、特点与存在问题,并对图书馆联盟之战略联盟进行了研究和探讨。%This article introduced the development,characteristics and the problems of library consortium,and then analyzed the feasibility of strategic alliance in library consortium.

  15. A National Consortium for Open Academic Books in Sweden : An investigation funded by National Library of Sweden, Swedish Research Council and Riksbankens Jubileumsfond

    OpenAIRE

    Lawrence, David; Bernhardsson, Katarina; Eriksson, Jörgen; Henning, Karin; Hertil Lindelöw, Camilla; Neidenmark, Thomas; Pelling, Maja; Svensson, Aina

    2013-01-01

    2. Concluding recommendations 2.1 Overall Academic books, particularly those published in Sweden and publically funded, should be made available via an open access version; Academic books should undergo an independent peer-review process; A national consortium should be set up that organizes a peer-review process for academic books and provides guidance on open access publishing; A consortium must work closely with existing publishing channels such as commercial publishers, Acta series and un...

  16. Enhancing the Decolorizing and Degradation Ability of Bacterial Consortium Isolated from Textile Effluent Affected Area and Its Application on Seed Germination

    Directory of Open Access Journals (Sweden)

    Rashid Mahmood

    2015-01-01

    Full Text Available A bacterial consortium BMP1/SDSC/01 consisting of six isolates was isolated from textile effected soil, sludge, and textile effluent from Hudiara drain near Nishat Mills Limited, Ferozepur Road, Lahore, Pakistan. It was selected because of being capable of degrading and detoxifying red, green, black, and yellow textile dyes. The pH and supplements were optimized to enhance the decolorization ability of the selected consortium. The results indicated that decolorizing ability of consortium for the red, green, black, and yellow dyes was higher as compared to individual strains. The consortium was able to decolorize 84%, 84%, 85%, 85%, and 82% of 200 ppm of red, green, black, yellow, and mixed dyes within 24 h while individual strain required 72 h. On supplementing urea, the consortium decolorized 87, 86, 89, 86, and 83%, respectively, while on supplementing sodium chloride the consortium decolorized 93, 94, 93, 94, and 89% of red, green, black, yellow, and mixed dyes, respectively, which was maximum while in the presence of ascorbic acid and ammonium chloride it showed intermediate results. The effect of untreated and treated dyes was investigated on Zea mays L. (maize and Sorghum vulgare Pers. (sorghum. This study will help to promote an efficient biotreatment of textile effluents.

  17. Enhancing the decolorizing and degradation ability of bacterial consortium isolated from textile effluent affected area and its application on seed germination.

    Science.gov (United States)

    Mahmood, Rashid; Sharif, Faiza; Ali, Sikander; Hayyat, Muhammad Umar

    2015-01-01

    A bacterial consortium BMP1/SDSC/01 consisting of six isolates was isolated from textile effected soil, sludge, and textile effluent from Hudiara drain near Nishat Mills Limited, Ferozepur Road, Lahore, Pakistan. It was selected because of being capable of degrading and detoxifying red, green, black, and yellow textile dyes. The pH and supplements were optimized to enhance the decolorization ability of the selected consortium. The results indicated that decolorizing ability of consortium for the red, green, black, and yellow dyes was higher as compared to individual strains. The consortium was able to decolorize 84%, 84%, 85%, 85%, and 82% of 200 ppm of red, green, black, yellow, and mixed dyes within 24 h while individual strain required 72 h. On supplementing urea, the consortium decolorized 87, 86, 89, 86, and 83%, respectively, while on supplementing sodium chloride the consortium decolorized 93, 94, 93, 94, and 89% of red, green, black, yellow, and mixed dyes, respectively, which was maximum while in the presence of ascorbic acid and ammonium chloride it showed intermediate results. The effect of untreated and treated dyes was investigated on Zea mays L. (maize) and Sorghum vulgare Pers. (sorghum). This study will help to promote an efficient biotreatment of textile effluents. PMID:25654132

  18. Low temperature reduction of hexavalent chromium by a microbial enrichment consortium and a novel strain of Arthrobacter aurescens

    Directory of Open Access Journals (Sweden)

    Thompson Vicki S

    2006-01-01

    Full Text Available Abstract Background Chromium is a transition metal most commonly found in the environment in its trivalent [Cr(III] and hexavalent [Cr(VI] forms. The EPA maximum total chromium contaminant level for drinking water is 0.1 mg/l (0.1 ppm. Many water sources, especially underground sources, are at low temperatures (less than or equal to 15 Centigrade year round. It is important to evaluate the possibility of microbial remediation of Cr(VI contamination using microorganisms adapted to these low temperatures (psychrophiles. Results Core samples obtained from a Cr(VI contaminated aquifer at the Hanford facility in Washington were enriched in Vogel Bonner medium at 10 Centigrade with 0, 25, 50, 100, 200, 400 and 1000 mg/l Cr(VI. The extent of Cr(VI reduction was evaluated using the diphenyl carbazide assay. Resistance to Cr(VI up to and including 1000 mg/l Cr(VI was observed in the consortium experiments. Reduction was slow or not observed at and above 100 mg/l Cr(VI using the enrichment consortium. Average time to complete reduction of Cr(VI in the 30 and 60 mg/l Cr(VI cultures of the consortium was 8 and 17 days, respectively at 10 Centigrade. Lyophilized consortium cells did not demonstrate adsorption of Cr(VI over a 24 hour period. Successful isolation of a Cr(VI reducing organism (designated P4 from the consortium was confirmed by 16S rDNA amplification and sequencing. Average time to complete reduction of Cr(VI at 10 Centigrade in the 25 and 50 mg/l Cr(VI cultures of the isolate P4 was 3 and 5 days, respectively. The 16S rDNA sequence from isolate P4 identified this organism as a strain of Arthrobacter aurescens, a species that has not previously been shown to be capable of low temperature Cr(VI reduction. Conclusion A. aurescens, indigenous to the subsurface, has the potential to be a predominant metal reducer in enhanced, in situ subsurface bioremediation efforts involving Cr(VI and possibly other heavy metals and radionuclides.

  19. A constructed alkaline consortium and its dynamics in treating alkaline black liquor with very high pollution load.

    Directory of Open Access Journals (Sweden)

    Chunyu Yang

    Full Text Available BACKGROUND: Paper pulp wastewater resulting from alkaline extraction of wheat straw, known as black liquor, is very difficult to be treated and causes serious environmental problems due to its high pH value and chemical oxygen demand (COD pollution load. Lignin, semicellulose and cellulose are the main contributors to the high COD values in black liquor. Very few microorganisms can survive in such harsh environments of the alkaline wheat straw black liquor. A naturally developed microbial community was found accidentally in a black liquor storing pool in a paper pulp mill of China. The community was effective in pH decreasing, color and COD removing from the high alkaline and high COD black liquor. FINDINGS: Thirty-eight strains of bacteria were isolated from the black liquor storing pool, and were grouped as eleven operational taxonomy units (OTUs using random amplified polymorphic DNA-PCR profiles (RAPD. Eleven representative strains of each OTU, which were identified as genera of Halomonas and Bacillus, were used to construct a consortium to treat black liquor with a high pH value of 11.0 and very high COD pollution load of 142,600 mg l(-1. After treatment by the constructed consortium, about 35.4% of color and 39,000 mg l(-1 (27.3% COD(cr were removed and the pH decreased to 7.8. 16S rRNA gene polymerase chain reaction denaturant gradient gel electrophoresis (PCR-DGGE and gas chromatography/mass spectrometry (GC/MS analysis suggested a two-stage treatment mechanism to elucidate the interspecies collaboration: Halomonas isolates were important in the first stage to produce organic acids that contributed to the pH decline, while Bacillus isolates were involved in the degradation of lignin derivatives in the second stage under lower pH conditions. CONCLUSIONS/SIGNIFICANCE: Tolerance to the high alkaline environment and good controllability of the simple consortium suggested that the constructed consortium has good potential for black liquor

  20. Residents' working hours in a consortium-wide surgical education program.

    Science.gov (United States)

    Mittal, Vijay; Salem, Madhavi; Tyburski, James; Brocato, Joseph; Lloyd, Larry; Silva, Yvan; Silbergleit, Allen; Shanley, Charles; Remine, Stephen

    2004-02-01

    Traditional work schedules of surgical residents have been cited as a factor that negatively influences education and the quality of patient care. Demands by federal and state legislators as well as the general public have forced a re-evaluation of the issue. Long working hours and resulting sleep deprivation affect the lives of residents profoundly, but the question remains does it lower the quality of medical care? The justification for the long hours is that they are vital to medical education, but residents are so drained by their schedules that they are rarely in the best state of mind to learn from their experiences. Under the scrutiny of the Resident Review Committee (RRC), many programs and institutions have been cited in the recent past in violation of resident working hour requirements. As a result, many institutions have implemented reforms, thereby reducing the number of citations they received. In spite of having the highest number of citations, the field of general surgery has failed to show any improvement. The Oakland Health Education Programme Center for Medical Education (OHEP), a consortium of 16 teaching hospitals in the State of Michigan, set out to review the components of general surgery residency training in order to be able to make recommendations that might assist program directors in making appropriate changes where necessary to enhance resident education and the quality of patient care as well as to meet the personal demands of residents. Questionnaires on residents' attitudes concerning their working hours and possible reforms were sent to all general surgery residency programs in the OHEP consortium. The questionnaire consisted of 25 questions divided into three major sections: the first section encompassed demographic information including current work hours and on-call schedules. The second section consisted of questions relating to attitudes toward work hours and the options for change. The third section consisted of questions that

  1. The Consortium of Advanced Residential Buildings (CARB) - A Building America Energy Efficient Housing Partnership

    Energy Technology Data Exchange (ETDEWEB)

    Robb Aldrich; Lois Arena; Dianne Griffiths; Srikanth Puttagunta; David Springer

    2010-12-31

    This final report summarizes the work conducted by the Consortium of Advanced Residential Buildings (CARB) (http://www.carb-swa.com/), one of the 'Building America Energy Efficient Housing Partnership' Industry Teams, for the period January 1, 2008 to December 31, 2010. The Building America Program (BAP) is part of the Department of Energy (DOE), Energy Efficiency and Renewable Energy, Building Technologies Program (BTP). The long term goal of the BAP is to develop cost effective, production ready systems in five major climate zones that will result in zero energy homes (ZEH) that produce as much energy as they use on an annual basis by 2020. CARB is led by Steven Winter Associates, Inc. with Davis Energy Group, Inc. (DEG), MaGrann Associates, and Johnson Research, LLC as team members. In partnership with our numerous builders and industry partners, work was performed in three primary areas - advanced systems research, prototype home development, and technical support for communities of high performance homes. Our advanced systems research work focuses on developing a better understanding of the installed performance of advanced technology systems when integrated in a whole-house scenario. Technology systems researched included: - High-R Wall Assemblies - Non-Ducted Air-Source Heat Pumps - Low-Load HVAC Systems - Solar Thermal Water Heating - Ventilation Systems - Cold-Climate Ground and Air Source Heat Pumps - Hot/Dry Climate Air-to-Water Heat Pump - Condensing Boilers - Evaporative condensers - Water Heating CARB continued to support several prototype home projects in the design and specification phase. These projects are located in all five program climate regions and most are targeting greater than 50% source energy savings over the Building America Benchmark home. CARB provided technical support and developed builder project case studies to be included in near-term Joule Milestone reports for the following community scale projects: - SBER Overlook at

  2. Ideonella sakaiensis sp. nov., isolated from a microbial consortium that degrades poly(ethylene terephthalate).

    Science.gov (United States)

    Tanasupawat, Somboon; Takehana, Toshihiko; Yoshida, Shosuke; Hiraga, Kazumi; Oda, Kohei

    2016-08-01

    A Gram-stain-negative, aerobic, non-spore-forming, rod-shaped bacterium, designed strain 201-F6T, was isolated from a microbial consortium that degrades poly(ethylene terephthalate) (PET) collected in Sakai city, Japan, and was characterized on the basis of a polyphasic taxonomic study. The cells were motile with a polar flagellum. The strain contained cytochrome oxidase and catalase. It grew within the pH range 5.5-9.0 (optimally at pH 7-7.5) and at 15-42 ºC (optimally at 30-37 ºC). The major isoprenoid quinone was ubiquinone with eight isoprene units (Q-8). C16 : 0, C17 : 0 cyclo, C18 :1ω7c and C12 : 0 2-OH were the predominant cellular fatty acids. The major polar lipids were phosphatidylethanolamine, lyso-phosphatidylethanolamine, phosphatidylglycerol and diphosphatidylglycerol. The G+C content of genomic DNA was 70.4 mol%. Phylogenetic analysis using the 16S rRNA gene sequences showed that strain 201-F6T was affiliated to the genus Ideonella, and was closely related to Ideonella dechloratans LMG 28178T (97.7 %) and Ideonella azotifigens JCM 15503T (96.6 %). Strain 201-F6T could be clearly distinguished from the related species of the genus Ideonella by its physiological and biochemical characteristics as well as by its phylogenetic position and DNA-DNA relatedness. Therefore, the strain represents a novel species of the genus Ideonella, for which the name Ideonella sakaiensis sp. nov. (type strain 201-F6T=NBRC 110686T=TISTR 2288T) is proposed. PMID:27045688

  3. Modeling and simulation challenges pursued by the Consortium for Advanced Simulation of Light Water Reactors (CASL)

    Science.gov (United States)

    Turinsky, Paul J.; Kothe, Douglas B.

    2016-05-01

    The Consortium for the Advanced Simulation of Light Water Reactors (CASL), the first Energy Innovation Hub of the Department of Energy, was established in 2010 with the goal of providing modeling and simulation (M&S) capabilities that support and accelerate the improvement of nuclear energy's economic competitiveness and the reduction of spent nuclear fuel volume per unit energy, and all while assuring nuclear safety. To accomplish this requires advances in M&S capabilities in radiation transport, thermal-hydraulics, fuel performance and corrosion chemistry. To focus CASL's R&D, industry challenge problems have been defined, which equate with long standing issues of the nuclear power industry that M&S can assist in addressing. To date CASL has developed a multi-physics "core simulator" based upon pin-resolved radiation transport and subchannel (within fuel assembly) thermal-hydraulics, capitalizing on the capabilities of high performance computing. CASL's fuel performance M&S capability can also be optionally integrated into the core simulator, yielding a coupled multi-physics capability with untapped predictive potential. Material models have been developed to enhance predictive capabilities of fuel clad creep and growth, along with deeper understanding of zirconium alloy clad oxidation and hydrogen pickup. Understanding of corrosion chemistry (e.g., CRUD formation) has evolved at all scales: micro, meso and macro. CFD R&D has focused on improvement in closure models for subcooled boiling and bubbly flow, and the formulation of robust numerical solution algorithms. For multiphysics integration, several iterative acceleration methods have been assessed, illuminating areas where further research is needed. Finally, uncertainty quantification and data assimilation techniques, based upon sampling approaches, have been made more feasible for practicing nuclear engineers via R&D on dimensional reduction and biased sampling. Industry adoption of CASL's evolving M

  4. The Arctic Research Consortium of the United States (ARCUS): Connecting Arctic Research

    Science.gov (United States)

    Rich, R. H.; Wiggins, H. V.; Creek, K. R.; Sheffield Guy, L.

    2015-12-01

    This presentation will highlight the recent activities of the Arctic Research Consortium of the United States (ARCUS) to connect Arctic research. ARCUS is a nonprofit membership organization of universities and institutions that have a substantial commitment to research in the Arctic. ARCUS was formed in 1988 to serve as a forum for planning, facilitating, coordinating, and implementing interdisciplinary studies of the Arctic; to act as a synthesizer and disseminator of scientific information on arctic research; and to educate scientists and the general public about the needs and opportunities for research in the Arctic. ARCUS, in collaboration with the broader science community, relevant agencies and organizations, and other stakeholders, coordinates science planning and educational activities across disciplinary and organizational boundaries. Examples of ARCUS projects include: Arctic Sea Ice Outlook - an international effort that provides monthly summer reports synthesizing community estimates of the expected sea ice minimum. Sea Ice for Walrus Outlook - a resource for Alaska Native subsistence hunters, coastal communities, and others that provides weekly reports with information on sea ice conditions relevant to walrus in Alaska waters. PolarTREC (Teachers and Researchers Exploring and Collaborating) - a program whereby K-12 educators and researchers work together in hands-on field experiences in the Arctic and Antarctic to advance polar science education. ArcticInfo mailing list, Witness the Arctic newsletter, and the Arctic Calendar - communication tools for the arctic science community to keep apprised of relevant news, meetings, and announcements. Coordination for the Study of Environmental Arctic Change (SEARCH) program, which aims to provide scientific understanding of arctic environmental change to help society understand and respond to a rapidly changing Arctic. More information about these and other ARCUS activities can be found at the ARCUS website at

  5. Conversion of Crude Oil to Methane by a Microbial Consortium Enriched From Oil Reservoir Production Waters

    Directory of Open Access Journals (Sweden)

    Carolina eBerdugo-Clavijo

    2014-05-01

    Full Text Available The methanogenic biodegradation of crude oil is an important process occurring in petroleum reservoirs and other oil-containing environments such as contaminated aquifers. In this process, syntrophic bacteria degrade hydrocarbon substrates to products such as acetate, and/or H2 and CO2 that are then used by methanogens to produce methane in a thermodynamically dependent manner. We enriched a methanogenic crude oil-degrading consortium from production waters sampled from a low temperature heavy oil reservoir. Alkylsuccinates indicative of fumarate addition to C5 and C6 n-alkanes were identified in the culture (above levels found in controls, corresponding to the detection of an alkyl succinate synthase gene (assA in the culture. In addition, the enrichment culture was tested for its ability to produce methane from residual oil in a sandstone-packed column system simulating a mature field. Methane production rates of up 5.8 μmol CH4/g of oil/day were measured in the column system. Amounts of produced methane were in relatively good agreement with hydrocarbon loss showing depletion of more than 50% of saturate and aromatic hydrocarbons. Microbial community analysis revealed that the enrichment culture was dominated by members of the genus Smithella, Methanosaeta, and Methanoculleus. However, a shift in microbial community occurred following incubation of the enrichment in the sandstone columns. Here, Methanobacterium sp. were most abundant, as were bacterial members of the genus Pseudomonas and other known biofilm forming organisms. Our findings show that microorganisms enriched from petroleum reservoir waters can bioconvert crude oil components to methane both planktonically and in sandstone-packed columns as test systems. Further, the results suggest that different organisms may contribute to oil biodegradation within different phases (e.g., planktonic versus sessile within a subsurface crude oil reservoir.

  6. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

    Science.gov (United States)

    Joubert, Bonnie R.; Felix, Janine F.; Yousefi, Paul; Bakulski, Kelly M.; Just, Allan C.; Breton, Carrie; Reese, Sarah E.; Markunas, Christina A.; Richmond, Rebecca C.; Xu, Cheng-Jian; Küpers, Leanne K.; Oh, Sam S.; Hoyo, Cathrine; Gruzieva, Olena; Söderhäll, Cilla; Salas, Lucas A.; Baïz, Nour; Zhang, Hongmei; Lepeule, Johanna; Ruiz, Carlos; Ligthart, Symen; Wang, Tianyuan; Taylor, Jack A.; Duijts, Liesbeth; Sharp, Gemma C.; Jankipersadsing, Soesma A.; Nilsen, Roy M.; Vaez, Ahmad; Fallin, M. Daniele; Hu, Donglei; Litonjua, Augusto A.; Fuemmeler, Bernard F.; Huen, Karen; Kere, Juha; Kull, Inger; Munthe-Kaas, Monica Cheng; Gehring, Ulrike; Bustamante, Mariona; Saurel-Coubizolles, Marie José; Quraishi, Bilal M.; Ren, Jie; Tost, Jörg; Gonzalez, Juan R.; Peters, Marjolein J.; Håberg, Siri E.; Xu, Zongli; van Meurs, Joyce B.; Gaunt, Tom R.; Kerkhof, Marjan; Corpeleijn, Eva; Feinberg, Andrew P.; Eng, Celeste; Baccarelli, Andrea A.; Benjamin Neelon, Sara E.; Bradman, Asa; Merid, Simon Kebede; Bergström, Anna; Herceg, Zdenko; Hernandez-Vargas, Hector; Brunekreef, Bert; Pinart, Mariona; Heude, Barbara; Ewart, Susan; Yao, Jin; Lemonnier, Nathanaël; Franco, Oscar H.; Wu, Michael C.; Hofman, Albert; McArdle, Wendy; Van der Vlies, Pieter; Falahi, Fahimeh; Gillman, Matthew W.; Barcellos, Lisa F.; Kumar, Ashish; Wickman, Magnus; Guerra, Stefano; Charles, Marie-Aline; Holloway, John; Auffray, Charles; Tiemeier, Henning W.; Smith, George Davey; Postma, Dirkje; Hivert, Marie-France; Eskenazi, Brenda; Vrijheid, Martine; Arshad, Hasan; Antó, Josep M.; Dehghan, Abbas; Karmaus, Wilfried; Annesi-Maesano, Isabella; Sunyer, Jordi; Ghantous, Akram; Pershagen, Göran; Holland, Nina; Murphy, Susan K.; DeMeo, Dawn L.; Burchard, Esteban G.; Ladd-Acosta, Christine; Snieder, Harold; Nystad, Wenche; Koppelman, Gerard H.; Relton, Caroline L.; Jaddoe, Vincent W.V.; Wilcox, Allen; Melén, Erik; London, Stephanie J.

    2016-01-01

    Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy remains an important public health problem that impacts child health in a myriad of ways and has potential lifelong consequences. The mechanisms are largely unknown, but epigenetics most likely plays a role. We formed the Pregnancy And Childhood Epigenetics (PACE) consortium and meta-analyzed, across 13 cohorts (n = 6,685), the association between maternal smoking in pregnancy and newborn blood DNA methylation at over 450,000 CpG sites (CpGs) by using the Illumina 450K BeadChip. Over 6,000 CpGs were differentially methylated in relation to maternal smoking at genome-wide statistical significance (false discovery rate, 5%), including 2,965 CpGs corresponding to 2,017 genes not previously related to smoking and methylation in either newborns or adults. Several genes are relevant to diseases that can be caused by maternal smoking (e.g., orofacial clefts and asthma) or adult smoking (e.g., certain cancers). A number of differentially methylated CpGs were associated with gene expression. We observed enrichment in pathways and processes critical to development. In older children (5 cohorts, n = 3,187), 100% of CpGs gave at least nominal levels of significance, far more than expected by chance (p value < 2.2 × 10−16). Results were robust to different normalization methods used across studies and cell type adjustment. In this large scale meta-analysis of methylation data, we identified numerous loci involved in response to maternal smoking in pregnancy with persistence into later childhood and provide insights into mechanisms underlying effects of this important exposure. PMID:27040690

  7. Athlome Project Consortium: a concerted effort to discover genomic and other "omic" markers of athletic performance.

    Science.gov (United States)

    Pitsiladis, Yannis P; Tanaka, Masashi; Eynon, Nir; Bouchard, Claude; North, Kathryn N; Williams, Alun G; Collins, Malcolm; Moran, Colin N; Britton, Steven L; Fuku, Noriyuki; Ashley, Euan A; Klissouras, Vassilis; Lucia, Alejandro; Ahmetov, Ildus I; de Geus, Eco; Alsayrafi, Mohammed

    2016-03-01

    Despite numerous attempts to discover genetic variants associated with elite athletic performance, injury predisposition, and elite/world-class athletic status, there has been limited progress to date. Past reliance on candidate gene studies predominantly focusing on genotyping a limited number of single nucleotide polymorphisms or the insertion/deletion variants in small, often heterogeneous cohorts (i.e., made up of athletes of quite different sport specialties) have not generated the kind of results that could offer solid opportunities to bridge the gap between basic research in exercise sciences and deliverables in biomedicine. A retrospective view of genetic association studies with complex disease traits indicates that transition to hypothesis-free genome-wide approaches will be more fruitful. In studies of complex disease, it is well recognized that the magnitude of genetic association is often smaller than initially anticipated, and, as such, large sample sizes are required to identify the gene effects robustly. A symposium was held in Athens and on the Greek island of Santorini from 14-17 May 2015 to review the main findings in exercise genetics and genomics and to explore promising trends and possibilities. The symposium also offered a forum for the development of a position stand (the Santorini Declaration). Among the participants, many were involved in ongoing collaborative studies (e.g., ELITE, GAMES, Gene SMART, GENESIS, and POWERGENE). A consensus emerged among participants that it would be advantageous to bring together all current studies and those recently launched into one new large collaborative initiative, which was subsequently named the Athlome Project Consortium. PMID:26715623

  8. The Human Toxome Collaboratorium: a shared environment for multi-omic computational collaboration within a consortium

    Directory of Open Access Journals (Sweden)

    Rick A Fasani

    2016-02-01

    Full Text Available The Human Toxome Project is part of a long-term vision to modernize toxicity testing for the 21st century. In the initial phase of the project, a consortium of six academic, commercial, and government organizations has partnered to map pathways of toxicity, using endocrine disruption as a model hazard. Experimental data is generated at multiple sites, and analyzed using a range of computational tools. While effectively gathering, managing, and analyzing the data for high-content experiments is a challenge in its own right, doing so for a growing number of -omics technologies, with larger data sets, across multiple institutions complicates the process. Interestingly, one of the most difficult, ongoing challenges has been the computational collaboration between the geographically separate institutions. Existing solutions cannot handle the growing heterogeneous data, provide a computational environment for consistent analysis, accommodate different workflows, and adapt to the constantly evolving methods and goals of a research project. To meet the needs of the project, we have created and managed The Human Toxome Collaboratorium, a shared computational environment hosted on third-party cloud services. The Collaboratorium provides a familiar virtual desktop, with a mix of commercial, open-source, and custom-built applications. It shares some of the challenges of traditional information technology, but with unique and unexpected constraints that emerge from the cloud. Here we describe the problems we faced, the current architecture of the solution, an example of its use, the major lessons we learned, and the future potential of the concept. In particular, the Collaboratorium represents a novel distribution method that could increase the reproducibility and reusability of results from similar large, multi-omic studies.

  9. Home pesticide exposures and risk of childhood leukemia: Findings from the childhood leukemia international consortium.

    Science.gov (United States)

    Bailey, Helen D; Infante-Rivard, Claire; Metayer, Catherine; Clavel, Jacqueline; Lightfoot, Tracy; Kaatsch, Peter; Roman, Eve; Magnani, Corrado; Spector, Logan G; Th Petridou, Eleni; Milne, Elizabeth; Dockerty, John D; Miligi, Lucia; Armstrong, Bruce K; Rudant, Jérémie; Fritschi, Lin; Simpson, Jill; Zhang, Luoping; Rondelli, Roberto; Baka, Margarita; Orsi, Laurent; Moschovi, Maria; Kang, Alice Y; Schüz, Joachim

    2015-12-01

    Some previous studies have suggested that home pesticide exposure before birth and during a child's early years may increase the risk of childhood leukemia. To further investigate this, we pooled individual level data from 12 case-control studies in the Childhood Leukemia International Consortium. Exposure data were harmonized into compatible formats. Pooled analyses were undertaken using multivariable unconditional logistic regression. The odds ratio (ORs) for acute lymphoblastic leukemia (ALL) associated with any pesticide exposure shortly before conception, during pregnancy and after birth were 1.39 (95% confidence interval [CI]: 1.25, 1.55) (using 2,785 cases and 3,635 controls), 1.43 (95% CI: 1.32, 1.54) (5,055 cases and 7,370 controls) and 1.36 (95% CI: 1.23, 1.51) (4,162 cases and 5,179 controls), respectively. Corresponding ORs for risk of acute myeloid leukemia (AML) were 1.49 (95% CI: 1.02, 2.16) (173 cases and 1,789 controls), 1.55 (95% CI: 1.21, 1.99) (344 cases and 4,666 controls) and 1.08 (95% CI: 0.76, 1.53) (198 cases and 2,655 controls), respectively. There was little difference by type of pesticide used. The relative similarity in ORs between leukemia types, time periods and pesticide types may be explained by similar exposure patterns and effects across the time periods in ALL and AML, participants' exposure to multiple pesticides, or recall bias. Although some recall bias is likely, until a better study design can be found to investigate the associations between home pesticide use and childhood leukemia in an equally large sample, it would appear prudent to limit the use of home pesticides before and during pregnancy, and during childhood.

  10. 医疗联合体的法学分析*%Legal Analysis on Medical Consortium

    Institute of Scientific and Technical Information of China (English)

    曹培杰; 刘子锋; 程跃华

    2013-01-01

    Medical Consortium(MC) recently appears in succession in some areas of our country. In this pa-per, by means of text analysis, from the perspective of jurisprudence, based on the theories of civil subject, legal persons'association and business association control, after comparing the official documents on MC from Shanghai Municipal Health Bureau and Zhengzhou Municipal Health Bureau, the author analyzes the following aspects comprehensively: the definition, governance structure, classification, legal attributes, internal and external rela-tionship and the existing problems of MC, thus puts forward some countermeasures and suggestions on the devel-opment mode of MC in China.%医疗联合体近年来在国内部分地区陆续出现。本文运用文本分析的方法,从法学视角以民事主体、法人联营和企业关联控制理论为依据,在重点比较上海市卫生局、郑州市卫生局关于医疗联合体的官方文件基础上,从“医疗联合体”概念,该联合体的治理结构、分类和法律属性、内外部关系以及所存在的问题等多方面进行综合分析,并对我国医疗联合体的发展模式等提出了对策建议。

  11. Optimization study for Pb(II) and COD sequestration by consortium of sulphate-reducing bacteria

    Science.gov (United States)

    Verma, Anamika; Bishnoi, Narsi R.; Gupta, Asha

    2016-04-01

    In this study, initial minimum inhibitory concentration (MIC) of Pb(II) ions was analysed to check optimum concentration of Pb(II) ions at which the growth of sulphate-reducing consortium (SRC) was found to be maximum. 80 ppm of Pb(II) ions was investigated as minimum inhibitory concentration for SRC. Influence of electron donors such as lactose, sucrose, glucose and sodium lactate was examined to investigate best carbon source for growth and activity of sulphate-reducing bacteria. Sodium lactate was found to be the prime carbon source for SRC. Later optimization of various parameters was executed using Box-Behnken design model of response surface methodology to explore the effectiveness of three independent operating variables, namely, pH (5.0-9.0), temperature (32-42 °C) and time (5.0-9.0 days), on dependent variables, i.e. protein content, precipitation of Pb(II) ions, and removal of COD by SRC biomass. Maximum removal of COD and Pb(II) was observed to be 91 and 98 %, respectively, at pH 7.0 and temperature 37 °C and incubation time 7 days. According to response surface analysis and analysis of variance, the experimental data were perfectly fitted to the quadratic model, and the interactive influence of pH, temperature and time on Pb(II) and COD removal was highly significant. A high regression coefficient between the variables and response (r 2 = 0.9974) corroborate eminent evaluation of experimental data by second-order polynomial regression model. SEM and Fourier transform infrared analysis was performed to investigate morphology of PbS precipitates, sorption mechanism and involved functional groups in metal-free and metal-loaded biomass of SRC for Pb(II) binding.

  12. Waste-Management Education and Research Consortium (WERC) annual progress report, 1992--1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-02-15

    In February, 1990, The Secretary of Energy, James Watkins, approved a grant for a waste (management) education and research consortium program proposed by New Mexico State University (NMSU) to the US Department of Energy (DOE). This program known by the acronym, WERC'' includes as its founding members NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology the Los Alamos National Laboratory, and the Sandia National Laboratories. The Navajo Community College joined the program later in 1991. The program has the mission of expanding the nation's capability to address the issues related to management of all types of waste. The program is unique and innovative in many aspects. It provides an integrated approach to this national need, and includes: (1) Education in waste management at the educational institutions resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. (2) Professional development via teleconference for industry and government. (3) Technology development programs at the leading edge, providing hands-on training at the leading edge to students and information feeding into the education programs. (4) Education by technology development at the campuses, as well as from four field sites. (5) Ties with other multidisciplinary university facilities. (6) Ties with two National Laboratories (Los Alamos Sandia) located in New Mexico and with the Oak Ridge Associated Universities and others. (7) Technology transfer and education via an existing fiber optic network, a satellite link, and an existing state-wide extension program. (8) Outreach programs of special interest to precollege students, communities and business and government leaders throughout the United States. This report summarizes the accomplishments and status at the end of the third year.

  13. Waste-Management Education and Research Consortium (WERC) annual progress report, 1992--1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-02-15

    In February, 1990, The Secretary of Energy, James Watkins, approved a grant for a waste (management) education and research consortium program proposed by New Mexico State University (NMSU) to the US Department of Energy (DOE). This program known by the acronym, ``WERC`` includes as its founding members NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology the Los Alamos National Laboratory, and the Sandia National Laboratories. The Navajo Community College joined the program later in 1991. The program has the mission of expanding the nation`s capability to address the issues related to management of all types of waste. The program is unique and innovative in many aspects. It provides an integrated approach to this national need, and includes: (1) Education in waste management at the educational institutions resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. (2) Professional development via teleconference for industry and government. (3) Technology development programs at the leading edge, providing hands-on training at the leading edge to students and information feeding into the education programs. (4) Education by technology development at the campuses, as well as from four field sites. (5) Ties with other multidisciplinary university facilities. (6) Ties with two National Laboratories (Los Alamos & Sandia) located in New Mexico and with the Oak Ridge Associated Universities and others. (7) Technology transfer and education via an existing fiber optic network, a satellite link, and an existing state-wide extension program. (8) Outreach programs of special interest to precollege students, communities and business and government leaders throughout the United States. This report summarizes the accomplishments and status at the end of the third year.

  14. A Description of the Clinical Proteomic Tumor Analysis Consortium (CPTAC) Common Data Analysis Pipeline.

    Science.gov (United States)

    Rudnick, Paul A; Markey, Sanford P; Roth, Jeri; Mirokhin, Yuri; Yan, Xinjian; Tchekhovskoi, Dmitrii V; Edwards, Nathan J; Thangudu, Ratna R; Ketchum, Karen A; Kinsinger, Christopher R; Mesri, Mehdi; Rodriguez, Henry; Stein, Stephen E

    2016-03-01

    The Clinical Proteomic Tumor Analysis Consortium (CPTAC) has produced large proteomics data sets from the mass spectrometric interrogation of tumor samples previously analyzed by The Cancer Genome Atlas (TCGA) program. The availability of the genomic and proteomic data is enabling proteogenomic study for both reference (i.e., contained in major sequence databases) and nonreference markers of cancer. The CPTAC laboratories have focused on colon, breast, and ovarian tissues in the first round of analyses; spectra from these data sets were produced from 2D liquid chromatography-tandem mass spectrometry analyses and represent deep coverage. To reduce the variability introduced by disparate data analysis platforms (e.g., software packages, versions, parameters, sequence databases, etc.), the CPTAC Common Data Analysis Platform (CDAP) was created. The CDAP produces both peptide-spectrum-match (PSM) reports and gene-level reports. The pipeline processes raw mass spectrometry data according to the following: (1) peak-picking and quantitative data extraction, (2) database searching, (3) gene-based protein parsimony, and (4) false-discovery rate-based filtering. The pipeline also produces localization scores for the phosphopeptide enrichment studies using the PhosphoRS program. Quantitative information for each of the data sets is specific to the sample processing, with PSM and protein reports containing the spectrum-level or gene-level ("rolled-up") precursor peak areas and spectral counts for label-free or reporter ion log-ratios for 4plex iTRAQ. The reports are available in simple tab-delimited formats and, for the PSM-reports, in mzIdentML. The goal of the CDAP is to provide standard, uniform reports for all of the CPTAC data to enable comparisons between different samples and cancer types as well as across the major omics fields. PMID:26860878

  15. A Description of the Clinical Proteomic Tumor Analysis Consortium (CPTAC) Common Data Analysis Pipeline.

    Science.gov (United States)

    Rudnick, Paul A; Markey, Sanford P; Roth, Jeri; Mirokhin, Yuri; Yan, Xinjian; Tchekhovskoi, Dmitrii V; Edwards, Nathan J; Thangudu, Ratna R; Ketchum, Karen A; Kinsinger, Christopher R; Mesri, Mehdi; Rodriguez, Henry; Stein, Stephen E

    2016-03-01

    The Clinical Proteomic Tumor Analysis Consortium (CPTAC) has produced large proteomics data sets from the mass spectrometric interrogation of tumor samples previously analyzed by The Cancer Genome Atlas (TCGA) program. The availability of the genomic and proteomic data is enabling proteogenomic study for both reference (i.e., contained in major sequence databases) and nonreference markers of cancer. The CPTAC laboratories have focused on colon, breast, and ovarian tissues in the first round of analyses; spectra from these data sets were produced from 2D liquid chromatography-tandem mass spectrometry analyses and represent deep coverage. To reduce the variability introduced by disparate data analysis platforms (e.g., software packages, versions, parameters, sequence databases, etc.), the CPTAC Common Data Analysis Platform (CDAP) was created. The CDAP produces both peptide-spectrum-match (PSM) reports and gene-level reports. The pipeline processes raw mass spectrometry data according to the following: (1) peak-picking and quantitative data extraction, (2) database searching, (3) gene-based protein parsimony, and (4) false-discovery rate-based filtering. The pipeline also produces localization scores for the phosphopeptide enrichment studies using the PhosphoRS program. Quantitative information for each of the data sets is specific to the sample processing, with PSM and protein reports containing the spectrum-level or gene-level ("rolled-up") precursor peak areas and spectral counts for label-free or reporter ion log-ratios for 4plex iTRAQ. The reports are available in simple tab-delimited formats and, for the PSM-reports, in mzIdentML. The goal of the CDAP is to provide standard, uniform reports for all of the CPTAC data to enable comparisons between different samples and cancer types as well as across the major omics fields.

  16. A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium.

    Directory of Open Access Journals (Sweden)

    James D McKay

    2011-03-01

    Full Text Available Genome-wide association studies (GWAS have been successful in identifying common genetic variation involved in susceptibility to etiologically complex disease. We conducted a GWAS to identify common genetic variation involved in susceptibility to upper aero-digestive tract (UADT cancers. Genome-wide genotyping was carried out using the Illumina HumanHap300 beadchips in 2,091 UADT cancer cases and 3,513 controls from two large European multi-centre UADT cancer studies, as well as 4,821 generic controls. The 19 top-ranked variants were investigated further in an additional 6,514 UADT cancer cases and 7,892 controls of European descent from an additional 13 UADT cancer studies participating in the INHANCE consortium. Five common variants presented evidence for significant association in the combined analysis (p ≤ 5 × 10⁻⁷. Two novel variants were identified, a 4q21 variant (rs1494961, p = 1×10⁻⁸ located near DNA repair related genes HEL308 and FAM175A (or Abraxas and a 12q24 variant (rs4767364, p =2 × 10⁻⁸ located in an extended linkage disequilibrium region that contains multiple genes including the aldehyde dehydrogenase 2 (ALDH2 gene. Three remaining variants are located in the ADH gene cluster and were identified previously in a candidate gene study involving some of these samples. The association between these three variants and UADT cancers was independently replicated in 5,092 UADT cancer cases and 6,794 controls non-overlapping samples presented here (rs1573496-ADH7, p = 5 × 10⁻⁸; rs1229984-ADH1B, p = 7 × 10⁻⁹; and rs698-ADH1C, p = 0.02. These results implicate two variants at 4q21 and 12q24 and further highlight three ADH variants in UADT cancer susceptibility.

  17. Evaluation of Open Geospatial Consortium Standards fur Use In LLNL Geographic Information Systems (GIS)

    Energy Technology Data Exchange (ETDEWEB)

    Walker, H; Chou, R; Chubb, K; Schek, J

    2005-09-28

    The objective of this project is to evaluate existing and emerging Open Geospatial Consortium (OGC) standards for use in LLNL programs that rely heavily on geographic data. OGC standards are intended to facilitate interoperability between geospatial processing systems to avoid duplication of effort, lower development costs, and encourage competition based on improved capability and performance rather than vendor lock-in. Some of these standards appear to be gaining traction in the geospatial data community, the Federal government, DOE and DHS. A serious evaluation of this technology is appropriate at this time due to increasing interest and mandated compliance in the Federal government in some situations. A subset of OGC standards is identified and reviewed with a focus on applications to LLNL programs. Each standard or recommendation reviewed was evaluated in general terms. In addition, for specific programs such as Gen&SIS and NARAC, a specific evaluation was made of several of the standards and how they could be used most effectively. It is also important to evaluate the acceptance of these standards in the commercial arena. The implementation of OGC standards by the largest GIS vendor (ESRI) was reviewed. At present, OGC standards are primary useful in specific situations. More generally, many of the standards are immature and their impact on the government and commercial sectors is unclear. Consequently, OGC and related developments need to be observed. As specific standards or groups of standards mature and establish their relevance, these can also be incorporated in LLNL programs as requirements dictate, especially if open implementations and commercial products are available.

  18. A quarter century of the Pacific Basin Consortium: looking back to move forward.

    Science.gov (United States)

    Suk, William A

    2016-03-01

    The Pacific Basin Consortium (PBC) was formed 25 years ago to address significant public health challenges to vulnerable populations imposed by environmental threats in the region, including areas surrounding the rim of and in the Pacific Ocean. Originally focused on toxic waste pollution, the PBC has broadened its efforts over the years, embracing a health focus and more of a balance between engineering and public health. This move was informed by the PBC's close relationship with the National Institutes of Health (NIH) National Institute of Environmental Health Sciences (NIEHS) Superfund Hazardous Substances Basic Research and Training Program (Superfund Research Program, or SRP), which played a dynamic role in the PBC from its early days. In addition, a sub-focus on children's environmental health emerged, which helped set the agenda for children's environmental health research in the region. Progress has also been made in reducing harm from some threats, particularly via extensive interventions to remediate arsenic in drinking water in Bangladesh, western Thailand, and Vietnam. However, many of the environmental health problems in the Pacific Basin region persist, including air pollution, inadequate safe drinking water, undernutrition, and a growing electronic waste problem. In the Pacific Basin and elsewhere, people with the lowest incomes often live in areas with the worst pollution. Although it is difficult to implement, dynamic strategic networking efforts are vital to understanding and correcting the inequities that persist in global environmental health. The PBC can help accomplish this by continuing and expanding its work to foster and enhance collaborations and communications between environmental health and engineering investigators and to integrate investigator-initiated research. As the PBC looks forward, there is also a need to exert increased effort to establish and maintain partnerships, to develop community-based primary-care and health services

  19. Waste-Management Education and Research Consortium (WERC) annual progress report, 1992--1993

    International Nuclear Information System (INIS)

    In February, 1990, The Secretary of Energy, James Watkins, approved a grant for a waste (management) education and research consortium program proposed by New Mexico State University (NMSU) to the US Department of Energy (DOE). This program known by the acronym, ''WERC'' includes as its founding members NMSU, the University of New Mexico (UNM), the New Mexico Institute of Mining and Technology the Los Alamos National Laboratory, and the Sandia National Laboratories. The Navajo Community College joined the program later in 1991. The program has the mission of expanding the nation's capability to address the issues related to management of all types of waste. The program is unique and innovative in many aspects. It provides an integrated approach to this national need, and includes: (1) Education in waste management at the educational institutions resulting in graduate, undergraduate, and associate degrees with concentration in environmental management. (2) Professional development via teleconference for industry and government. (3) Technology development programs at the leading edge, providing hands-on training at the leading edge to students and information feeding into the education programs. (4) Education by technology development at the campuses, as well as from four field sites. (5) Ties with other multidisciplinary university facilities. (6) Ties with two National Laboratories (Los Alamos ampersand Sandia) located in New Mexico and with the Oak Ridge Associated Universities and others. (7) Technology transfer and education via an existing fiber optic network, a satellite link, and an existing state-wide extension program. (8) Outreach programs of special interest to precollege students, communities and business and government leaders throughout the United States. This report summarizes the accomplishments and status at the end of the third year

  20. Final Technical Report. DeepCwind Consortium Research Program. January 15, 2010 - March 31, 2013

    Energy Technology Data Exchange (ETDEWEB)

    Dagher, Habib [Univ. of Maine, Orono, ME (United States); Viselli, Anthony [Univ. of Maine, Orono, ME (United States); Goupee, Andrew [Univ. of Maine, Orono, ME (United States); Thaler, Jeffrey [Univ. of Maine, Orono, ME (United States); Brady, Damian [Univ. of Maine, Orono, ME (United States); Browne, Peter [HDR, Inc., Omaha, NE (United States); Browning, James [Univ. of Colorado, Boulder, CO (United States); Chung, Jade [Univ. of Maine, Orono, ME (United States); Coulling, Alexander [Univ. of Maine, Orono, ME (United States); Deese, Heather [Island Institute, Rockland, ME (United States); Fowler, Matthew [Univ. of Maine, Orono, ME (United States); Holberton, Rebecca [Univ. of Maine, Orono, ME (United States); Anant, Jain [Intertek, Duluth, GA (United States); Jalbert, Dustin [Univ. of Maine, Orono, ME (United States); Johnson, Theresa [Univ. of Maine, Orono, ME (United States); Jonkman, Jason [National Renewable Energy Laboratory, Golden, CO (United States); Karlson, Benjamin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kimball, Richard [Maine Maritime Academy, Castine, ME (United States); Koo, Bonjun [Technip, Paris (France); Lackner, Matthew [Univ. of Massachusetts, Amherst, MA (United States); Lambrakos, Kostas [Technip, Paris (France); Lankowski, Matthew [Univ. of Maine, Orono, ME (United States); Leopold, Adrienne [Univ. of Maine, Orono, ME (United States); Lim, Ho-Joon [Technip, Paris (France); Mangum, Linda [Univ. of Maine, Orono, ME (United States); Martin, Heather [Univ. of Maine, Orono, ME (United States); Masciola, Marco [National Renewable Energy Laboratory, Golden, CO (United States); Maynard, Melissa [Univ. of Maine, Orono, ME (United States); McCleave, James [Univ. of Maine, Orono, ME (United States); Mizrahi, Robert [New Jersey Audubon Society, Bernardsville, NJ (United States); Molta, Paul [National Renewable Energy Laboratory, Golden, CO (United States); Pershing, Andrew [Gulf of Maine Research Institute, Portland, ME (United States); Pettigrew, Neal [Univ. of Maine, Orono, ME (United States); Prowell, Ian [MMI Engineering, Oakland, CA (United States); Qua, Andrew [Kleinschmidt Associates, Pittsfield, ME (United States); Sherwood, Graham [Gulf of Maine Research Institute, Portland, ME (United States); Snape, Thomas [Univ. of Maine, Orono, ME (United States); Steneck, Robert [Univ. of Maine, Orono, ME (United States); Stewart, Gordon [Univ. of Massachusetts, Amherst, MA (United States); Stockwell, Jason [Gulf of Maine Research Institute, Portland, ME (United States); Swift, Andrew H. P. [Texas Tech Univ., Lubbock, TX (United States); Thomas, Dale [Maine Maritime Academy, Castine, ME (United States); Viselli, Elizabeth [Univ. of Maine, Orono, ME (United States); Zydlewski, Gayle [Univ. of Maine, Orono, ME (United States)

    2013-06-11

    This is the final technical report for the U.S. Department of Energy-funded program, DE-0002981: DeepCwind Consortium Research Program. The project objective was the partial validation of coupled models and optimization of materials for offshore wind structures. The United States has a great opportunity to harness an indigenous abundant renewable energy resource: offshore wind. In 2010, the National Renewable Energy Laboratory (NREL) estimated there to be over 4,000 GW of potential offshore wind energy found within 50 nautical miles of the US coastlines (Musial and Ram, 2010). The US Energy Information Administration reported the total annual US electric energy generation in 2010 was 4,120 billion kilowatt-hours (equivalent to 470 GW) (US EIA, 2011), slightly more than 10% of the potential offshore wind resource. In addition, deep water offshore wind is the dominant US ocean energy resource available comprising 75% of the total assessed ocean energy resource as compared to wave and tidal resources (Musial, 2008). Through these assessments it is clear offshore wind can be a major contributor to US energy supplies. The caveat to capturing offshore wind along many parts of the US coast is deep water. Nearly 60%, or 2,450 GW, of the estimated US offshore wind resource is located in water depths of 60 m or more (Musial and Ram, 2010). At water depths over 60 m building fixed offshore wind turbine foundations, such as those found in Europe, is likely economically infeasible (Musial et al., 2006). Therefore floating wind turbine technology is seen as the best option for extracting a majority of the US offshore wind energy resource. Volume 1 - Test Site; Volume 2 - Coupled Models; and Volume 3 - Composite Materials