WorldWideScience

Sample records for chemistry manufacturing controls

  1. 75 FR 36421 - Draft Guidance for Industry on Chemistry, Manufacturing, and Controls Postapproval Manufacturing...

    Science.gov (United States)

    2010-06-25

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Chemistry, Manufacturing, and Controls Postapproval Manufacturing Changes Reportable in Annual Reports; Availability AGENCY: Food and... the availability of a draft guidance for industry entitled ``CMC Postapproval Manufacturing...

  2. 76 FR 13629 - Draft Guidance for Industry on Chemistry, Manufacturing, and Controls Information-Fermentation...

    Science.gov (United States)

    2011-03-14

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry on Chemistry, Manufacturing, and... guidance for industry 216 entitled ``Chemistry, Manufacturing, and Controls (CMC) Information--Fermentation...: The Food and Drug Administration (FDA) is announcing the availability of a draft guidance for...

  3. 75 FR 47604 - Guidance for Industry on Drug Substance Chemistry, Manufacturing, and Controls Information...

    Science.gov (United States)

    2010-08-06

    ... availability of a guidance for industry 169 entitled ``Drug Substance Chemistry, Manufacturing, and Controls... Federal Register of June 1, 2006 (71 FR 31194), FDA published the notice of withdrawal and revision of... HUMAN SERVICES Food and Drug Administration (formerly 2003D-0571) Guidance for Industry on...

  4. Analytical chemistry in semiconductor manufacturing: Techniques, role of nuclear methods and need for quality control

    International Nuclear Information System (INIS)

    This report is the result of a consultants meeting held in Gaithersburg, USA, 2-3 October 1987. The meeting was hosted by the National Bureau of Standards and Technology, and it was attended by 18 participants from Denmark, Finland, India, Japan, Norway, People's Republic of China and the USA. The purpose of the meeting was to assess the present status of analytical chemistry in semiconductor manufacturing, the role of nuclear analytical methods and the need for internationally organized quality control of the chemical analysis. The report contains the three presentations in full and a summary report of the discussions. Thus, it gives an overview of the need of analytical chemistry in manufacturing of silicon based devices, the use of nuclear analytical methods, and discusses the need for quality control. Refs, figs and tabs

  5. 77 FR 14022 - Guidance for Industry on Chemistry, Manufacturing, and Controls Information-Fermentation-Derived...

    Science.gov (United States)

    2012-03-08

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry on Chemistry, Manufacturing, and... INFORMATION: I. Background In the Federal Register of March 14, 2011 (76 FR 13629), FDA published the notice...: The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry...

  6. Robust Manufacturing Control

    CERN Document Server

    2013-01-01

    This contributed volume collects research papers, presented at the CIRP Sponsored Conference Robust Manufacturing Control: Innovative and Interdisciplinary Approaches for Global Networks (RoMaC 2012, Jacobs University, Bremen, Germany, June 18th-20th 2012). These research papers present the latest developments and new ideas focusing on robust manufacturing control for global networks. Today, Global Production Networks (i.e. the nexus of interconnected material and information flows through which products and services are manufactured, assembled and distributed) are confronted with and expected to adapt to: sudden and unpredictable large-scale changes of important parameters which are occurring more and more frequently, event propagation in networks with high degree of interconnectivity which leads to unforeseen fluctuations, and non-equilibrium states which increasingly characterize daily business. These multi-scale changes deeply influence logistic target achievement and call for robust planning and control ...

  7. Design and additive manufacture for flow chemistry.

    Science.gov (United States)

    Capel, Andrew J; Edmondson, Steve; Christie, Steven D R; Goodridge, Ruth D; Bibb, Richard J; Thurstans, Matthew

    2013-12-01

    We review the use of additive manufacturing (AM) as a novel manufacturing technique for the production of milli-scale reactor systems. Five well-developed additive manufacturing techniques: stereolithography (SL), multi-jet modelling (MJM), selective laser melting (SLM), laser sintering (LS) and fused deposition modelling (FDM) were used to manufacture a number of miniaturised reactors which were tested using a range of organic and inorganic reactions. PMID:24100659

  8. Bifurcation Control, Manufacturing Planning and Formation Control

    Institute of Scientific and Technical Information of China (English)

    Wei Kang; Mumin Song; Ning Xi

    2005-01-01

    The paper consists of three topics on control theory and engineering applications, namely bifurcation control, manufacturing planning, and formation control. For each topic, we summarize the control problem to be addressed and some key ideas used in our recent research. Interested readers are referred to related publications for more details. Each of the three topics in this paper is technically independent from the other ones. However, all three parts together reflect the recent research activities of the first author, jointly with other researchers in different fields.

  9. Regulatory control of fuel design and manufacturing

    International Nuclear Information System (INIS)

    The regulatory control of the design and manufacturing of the nuclear fuel and of the control rods aims to ensure conformance to set requirements during normal operating conditions, anticipated operational transients and postulated accident conditions. The regulatory control of design, manufacturing, receiving inspections and the start of operation of the nuclear fuel are specified in the guide. The regulatory control procedure also applies to the control rods and the shield elements

  10. Fundamentals of semiconductor manufacturing and process control

    CERN Document Server

    May, Gary S

    2006-01-01

    A practical guide to semiconductor manufacturing from process control to yield modeling and experimental design Fundamentals of Semiconductor Manufacturing and Process Control covers all issues involved in manufacturing microelectronic devices and circuits, including fabrication sequences, process control, experimental design, process modeling, yield modeling, and CIM/CAM systems. Readers are introduced to both the theory and practice of all basic manufacturing concepts. Following an overview of manufacturing and technology, the text explores process monitoring methods, including those that focus on product wafers and those that focus on the equipment used to produce wafers. Next, the text sets forth some fundamentals of statistics and yield modeling, which set the foundation for a detailed discussion of how statistical process control is used to analyze quality and improve yields. The discussion of statistical experimental design offers readers a powerful approach for systematically varying controllable p...

  11. Handbook of Manufacturing Control Fundamentals, description, configuration

    CERN Document Server

    Lödding, Hermann

    2013-01-01

    This first-time English publication of one of Germany’s leading manufacturing control handbooks provides a comprehensive overview of the state of the art, with detailed and easy to understand descriptions of numerous control techniques from Kanban to CONWIP to Backlog Control. Based on the proven funnel model and written for the industry, this book clearly illustrates how companies can use manufacturing control to effectively improve on-time delivery, reduce inventories and cut down throughput times. “This book distinguishes itself with its convincing systematic approach based on thorough international research. Its clear presentation and direct applicability for analysing and configuring the manufacturing control make this handbook an outstanding and unique publication on PPC.” Hans-Peter Wiendahl “The field of manufacturing control is very convincingly reviewed and presented from a theoretical and methodological perspective. Both researchers as well as practitioners will profit from it.” Peter N...

  12. Manufacturing control: A basis for analysis

    Science.gov (United States)

    Bugg, N.

    1989-11-01

    The application of elementary control theory to manufacturing systems demonstrating how the organization of basic shop-floor logistics can be optimized prior to the introduction of computer technology is explored. A control structure is introduced and applied to manufacturing systems, breaking the problem into its constituent parts in such a way that the advantages of improved control technology become more apparent and more readily implementable.

  13. Multi Agent and Holonic Manufacturing Control

    OpenAIRE

    Nejad, Hossein Tehrani Nik; Sugimura, Nobuhiro; Iwamura, Koji

    2010-01-01

    Manufacturing companies at the beginning of 21th century have to face a dynamic environment where economical, technological and customer trends change rapidly, requiring the increase of flexibility and agility to react to unexpected disturbances, maintaining the productivity and quality parameters. The traditional manufacturing control systems are adapted on a case-by- case basis, requiring an expensive and huge time-consuming effort to develop, maintain or re-configure. The missing re- confi...

  14. 75 FR 63188 - Draft Guidance for Industry: Early Clinical Trials With Live Biotherapeutic Products: Chemistry...

    Science.gov (United States)

    2010-10-14

    ... Biotherapeutic Products: Chemistry, Manufacturing, and Control Information; Availability AGENCY: Food and Drug... Biotherapeutic Products: Chemistry, Manufacturing, and Control Information'' dated September 2010. The draft... Live Biotherapeutic Products: Chemistry, Manufacturing, and Control Information'' dated September...

  15. 78 FR 49546 - Manufacturer of Controlled Substances; Notice of Application; IRIX Manufacturing, Inc.

    Science.gov (United States)

    2013-08-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; IRIX Manufacturing... that on January 18, 2013, IRIX Manufacturing, Inc., 309 Delaware Street, Greenville, South...

  16. Minimum Analytical Chemistry Requirements for Pit Manufacturing at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Moy, Ming M.; Leasure, Craig S.

    1998-08-01

    Analytical chemistry is one of several capabilities necessary for executing the Stockpile Stewardship and Management Program at Los Alamos National Laboratory (LANL). Analytical chemistry capabilities reside in the Chemistry Metallurgy Research (CMR) Facility and Plutonium Facility (TA-55). These analytical capabilities support plutonium recovery operations, plutonium metallurgy, and waste management. Analytical chemistry capabilities at both nuclear facilities are currently being configured to support pit manufacturing. This document summarizes the minimum analytical chemistry capabilities required to sustain pit manufacturing at LANL. By the year 2004, approximately $16 million will be required to procure analytical instrumentation to support pit manufacturing. In addition, $8.5 million will be required to procure glovebox enclosures. An estimated 50% increase in costs has been included for installation of analytical instruments and glovebox enclosures. However, no general and administrative (G and A) taxes have been included. If an additional 42.5/0 G and A tax were to be incurred, approximately $35 million would be required over the next five years to prepare analytical chemistry to support a 50-pit-per-year manufacturing capability by the year 2004.

  17. CO2 quotas: the chemistry manufacturers demand more transparency

    International Nuclear Information System (INIS)

    The EU emissions trading system (EU ETS) is entering in its third phase bearing on the 2013-2050 period. If they don't question about the requirement to regulate the CO2 market, the manufacturers wonder on the future of the EU emissions trading system at longer term and ask for more transparency. (O.M.)

  18. Interrelation of chemistry and process design in biodiesel manufacturing by heterogeneous catalysis

    OpenAIRE

    Dimian, A.C.; Srokol, Z.W.; Mittelmeijer-Hazeleger, M.C.; Rothenberg, G.

    2010-01-01

    The pros and cons of using heterogeneous catalysis for biodiesel manufacturing are introduced, and explained from a chemistry and engineering viewpoint. Transesterification reactions of various feed types are then compared in batch and continuous process operation modes. The results show that the reaction chemistry and process kinetics characterising a particular feedstock are determinant factors for obtaining high-grade biodiesel. When using heterogeneous catalysis, the biodiesel quality of ...

  19. Microeconomics of process control in semiconductor manufacturing

    Science.gov (United States)

    Monahan, Kevin M.

    2003-06-01

    Process window control enables accelerated design-rule shrinks for both logic and memory manufacturers, but simple microeconomic models that directly link the effects of process window control to maximum profitability are rare. In this work, we derive these links using a simplified model for the maximum rate of profit generated by the semiconductor manufacturing process. We show that the ability of process window control to achieve these economic objectives may be limited by variability in the larger manufacturing context, including measurement delays and process variation at the lot, wafer, x-wafer, x-field, and x-chip levels. We conclude that x-wafer and x-field CD control strategies will be critical enablers of density, performance and optimum profitability at the 90 and 65nm technology nodes. These analyses correlate well with actual factory data and often identify millions of dollars in potential incremental revenue and cost savings. As an example, we show that a scatterometry-based CD Process Window Monitor is an economically justified, enabling technology for the 65nm node.

  20. A system approach to controlling semiconductor manufacturing operations

    OpenAIRE

    Σταυράκης, Γιώργος Δ.

    1987-01-01

    Semicoductor manufacturers, faced with stiffening competition in both product cost and quality, require improved utilization of their development and manufacturing resources. Manufacturing philosophy must be changed, from focusing on short term results, to support continuous improvements in both output and quality. Such improvements demand better information management to monitor and control the manufacturing process. From these considerations, a process control methodology was develope...

  1. Lithological control on soil chemistry, Northern Ireland

    OpenAIRE

    Ashton, Nicola; Pattrick, R. A. D.; J. R. Lloyd; B. E. van Dongen; Tye, A.

    2011-01-01

    The geological diversity of Northern Ireland provides a unique opportunity to investigate the effects of differing lithologies upon the (organic) geochemistry of overlying soils. This will aid the understanding of how this influences the microbial populations within the soil and their role in biochemical cycling. Whilst several factors contribute to the properties of developing soils, source rock is one of the major controls in determining chemistry and formation rate (Chengmin et al., 2...

  2. Controlling Chemistry in Dynamic Nanoscale Systems

    DEFF Research Database (Denmark)

    Jesorka, Aldo; Lizana, Ludvig; Konkoli, Zoran; Czolkos, Ilja; Orwar, Owe

    Spatial organization and shape dynamics are inherent properties of biological cells and cell interiors. There are strong indications that these features are important for the in vivo control of reaction parameters in biochemical transformations. Nanofluidic model devices founded on surfactant...... concept. Controlled release of chol-DNA molecules from SU-8 surfaces gives the possibility to dynamically change surface and/or solution properties in micro and nanoreactor applications, opening access to stable 2D chemistry on surface-based devices with potential for easy interfacing with conventional...

  3. Crevice chemistry control in PWR steam generators

    International Nuclear Information System (INIS)

    To establish a basis for predicting and eventually controlling crevice solution chemistry in PWR steam generators, hideout tests were performed at several units. Results indicated that impurity hideout rates varied with the species and with bulk water concentration. Field evaluations of crevice impurity inventory models based on the hideout rate data indicated that further model refinements were necessary, e.g., more frequent quantification of the relation of hideout rates and bulk water concentration. An alternate crevice inventory model based on a real-time mass balance approach also began to be pursued. Modeling results currently are being used at several PWRs to establish a chloride injection rate consistent with development of a near neutral crevice solution to minimize IGA/SCC. Hideout return data are being used to independently establish predictions of crevice chemistry and to substantiate the hideout rate and mass balance model predictions

  4. 76 FR 51401 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-08-18

    ... classes of controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The... customers. In reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol...

  5. An RFID-Based Manufacturing Control Framework for Loosely Coupled Distributed Manufacturing System Supporting Mass Customization

    Science.gov (United States)

    Chen, Ruey-Shun; Tsai, Yung-Shun; Tu, Arthur

    In this study we propose a manufacturing control framework based on radio-frequency identification (RFID) technology and a distributed information system to construct a mass-customization production process in a loosely coupled shop-floor control environment. On the basis of this framework, we developed RFID middleware and an integrated information system for tracking and controlling the manufacturing process flow. A bicycle manufacturer was used to demonstrate the prototype system. The findings of this study were that the proposed framework can improve the visibility and traceability of the manufacturing process as well as enhance process quality control and real-time production pedigree access. Using this framework, an enterprise can easily integrate an RFID-based system into its manufacturing environment to facilitate mass customization and a just-in-time production model.

  6. Additive Manufacturing: Multi Material Processing and Part Quality Control

    DEFF Research Database (Denmark)

    Pedersen, David Bue

    This Ph.D dissertation,ffAdditive Manufacturing: Multi Material Processing and Part Quality Controlff, deal with Additive Manufacturing technologies which is a common name for a series of processes that are recognized by being computer controlled, highly automated, and manufacture objects by a...... layered deposition of material. Two areas of particular interest is addressed. They are rooted in two very different areas, yet is intended to fuel the same goal. To help Additive Manufacturing technologies one step closer to becoming the autonomous, digital manufacturing method of tomorrow. Vision...... systems A paradox exist in the field of Additive Manufacturing. The technologies allow for close-to unrestrained and integral geometrical freedom. Almost any geometry can be manufactured fast, e"ciently and cheap. Something that has been missing fundamental capability since the entering of the industrial...

  7. Study on the Architecture of Control System for Manufacturing Cells

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The depiction of the agile manufacturing cell includes a synopsis of some of the change proficiencies obtained by the configuration. To achieve agile configuration, the cell control system for agile manufacturing must be rapidly and efficiently generated or modified. In this paper, the object-oriented architecture is defined that supports design and implementation of highly reconfigurable control systems for agile manufacturing cells, which is composed of database objects, control objects, and resource objects, so as to reduce costs and to increase the control system's agility with respect to changing environment.

  8. Logic control law design for automated manufacturing systems

    OpenAIRE

    Sébastien, Henry; Zamaï, Éric; Jacomino, Mireille

    2012-01-01

    To respond rapidly to the highly volatile market, the reconfigurable manufacturing systems (RMS) have brought forward challenging issues. First of all there is a need to build a formal model of a manufacturing configuration. Second it has to be rather easy to derive the models associated to the manufacturing configuration changes (reconfiguration) from such an initial model. An off-line method of rapid design of an optimal logic control law (configuration) based on Petri net (PN) is presented...

  9. Communication and control in small batch part manufacturing

    NARCIS (Netherlands)

    Tiemersma, J.J.; Curtis, W.; Kals, H.J.J.

    1993-01-01

    This paper reports on the development of a real-time control network as an integrated part of a shop floor control system for small batch part manufacturing. The shop floor control system is called the production control system (PCS). The PCS aims at an improved control of small batch part manufactu

  10. 75 FR 64744 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-10-20

    ... controlled substances listed in schedule I: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to manufacture small quantities of marihuana derivatives for research purposes. In reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol. In reference...

  11. Geochemical controls on groundwater chemistry in shales

    International Nuclear Information System (INIS)

    The chemistry of groundwaters is one of the most important parameters in determining the mobility of species within a rock formation. A three pronged approach was used to determine the composition of, and geochemical controls, on groundwaters specifically within shale formations: (1) available data were collected from the literature, the US Geological Survey WATSTORE data base, and field sampling, (2) the geochemical modeling code EQ3/6 was used to simulate interaction of various shales and groundwaters, and (3) several types of shale were reacted with synthetic groundwaters in the laboratory. The comparison of model results to field and laboratory data provide a means of validating the models, as well as a means of deconvoluting complex field interactions. Results suggest that groundwaters in shales have a wide range in composition and are primarily of the Na-Cl-HCO3- type. The constancy of the Na:Cl (molar) ratio at 1:1 and the Ca:Mg ratio from 3:1 to 1:1 suggests the importance of halite and carbonates in controlling groundwater compositions. In agreement with the reaction path modeling, most of the groundwaters are neutral to slightly alkaline at low temperatures. Model and experimental results suggest that reaction (1) at elevated temperatures, or (2) in the presence of oxygen will lead to more acidic conditions. Some acetate was found to be produced in the experiments; depending on the constraints applied, large amounts of acetate were produced in the model results. 13 refs., 1 tab

  12. Research of user access control for networked manufacturing system

    Institute of Scientific and Technical Information of China (English)

    ZHENG Xiao-lin; LEI Yu; CHEN De-ren

    2006-01-01

    An integrated user access control method was proposed to address the issues of security and management in networked manufacturing systems (NMS).Based on the analysis of the security issues in networked manufacturing system,an integrated user access control method composed of role-based access control (RBAC),task-based access control (TBAC),relationship-driven access control (RDAC)and coalition-based access control (CBAC) was proposed,including the hierarchical user relationship model,the reference model and the process model.The elements and their relationships were defined,and the expressions of constraints authorization were given.The extensible access control markup language (XACML) was used to implement this method.This method was used in the networked manufacturing system in the Shaoxing spinning region of China.The results show that the integrated user access control method can reduce the costs of system security maintenance and management.

  13. Microstructural Control of Additively Manufactured Metallic Materials

    Science.gov (United States)

    Collins, P. C.; Brice, D. A.; Samimi, P.; Ghamarian, I.; Fraser, H. L.

    2016-07-01

    In additively manufactured (AM) metallic materials, the fundamental interrelationships that exist between composition, processing, and microstructure govern these materials’ properties and potential improvements or reductions in performance. For example, by using AM, it is possible to achieve highly desirable microstructural features (e.g., highly refined precipitates) that could not otherwise be achieved by using conventional approaches. Simultaneously, opportunities exist to manage macro-level microstructural characteristics such as residual stress, porosity, and texture, the last of which might be desirable. To predictably realize optimal microstructures, it is necessary to establish a framework that integrates processing variables, alloy composition, and the resulting microstructure. Although such a framework is largely lacking for AM metallic materials, the basic scientific components of the framework exist in literature. This review considers these key components and presents them in a manner that highlights key interdependencies that would form an integrated framework to engineer microstructures using AM.

  14. Composite materials pipings: selection of basic materials and manufacturing process, quality control during manufacture

    International Nuclear Information System (INIS)

    The purpose of the paper is to present a summary of the knowledge acquired at the R and D on resins used as composite matrix, the resistance to hydrolysis and mechanical strength of pipings made from these materials, and on quality control during manufacture. The initial targets concerning the material selection, industrial manufacturing and quality control procedures are presented. The paper describes the results obtained concerning the investigation of the damage produced by hydrolysis in polyesters, vinyl esters and epoxides, the influence of temperature, reinforcement and the mechanical characterization of the tubing manufacturing. The performances of the nondestructive testings (radiography, ultrasonic controls, differential interferometry and infrared thermography) used are also reported. The paper ends with a further research and testings programme. (author)

  15. Acarine attractants: Chemoreception, bioassay, chemistry and control.

    Science.gov (United States)

    Carr, Ann L; Roe, Michael

    2016-07-01

    The Acari are of significant economic importance in crop production and human and animal health. Acaricides are essential for the control of these pests, but at the same time, the number of available pesticides is limited, especially for applications in animal production. The Acari consist of two major groups, the mites that demonstrate a wide variety of life strategies, i.e., herbivory, predation and ectoparasitism, and ticks which have evolved obligatory hematophagy. The major sites of chemoreception in the acarines are the chelicerae, palps and tarsi on the forelegs. A unifying name, the "foretarsal sensory organ" (FSO), is proposed for the first time in this review for the sensory site on the forelegs of all acarines. The FSO has multiple sensory functions including olfaction, gustation, and heat detection. Preliminary transcriptomic data in ticks suggest that chemoreception in the FSO is achieved by a different mechanism from insects. There are a variety of laboratory and field bioassay methods that have been developed for the identification and characterization of attractants but minimal techniques for electrophysiology studies. Over the past three to four decades, significant progress has been made in the chemistry and analysis of function for acarine attractants in mites and ticks. In mites, attractants include aggregation, immature female, female sex and alarm pheromones; in ticks, the attraction-aggregation-attachment, assembly and sex pheromones; in mites and ticks host kairomones and plant allomones; and in mites, fungal allomones. There are still large gaps in our knowledge of chemical communication in the acarines compared to insects, especially relative to acarine pheromones, and more so for mites than ticks. However, the use of lure-and-kill and lure-enhanced biocontrol strategies has been investigated for tick and mite control, respectively, with significant environmental advantages which warrant further study. PMID:27265828

  16. Component-based Control Software Design for Flexible Manufacturing System

    Institute of Scientific and Technical Information of China (English)

    周炳海; 奚立峰; 曹永上

    2003-01-01

    A new method that designs and implements the component-based distributed & hierarchical flexible manufacturing control software is described with a component concept in this paper. The proposed method takes aim at improving the flexibility and reliability of the control system. On the basis of describing the concepts of component-based software and the distributed object technology, the architecture of the component-based software of the control system is suggested with the Common Object Request Broker Architecture (CORBA). And then, we propose a design method for component-based distributed & hierarchical flexible manufacturing control system. Finally, to verify the software design method, a prototype flexible manufacturing control system software has been implemented in Orbix 2. 3c, VC++6.0 and has been tested in connection with the physical flexible ranufacturing shop at the WuXi Professional Institute.

  17. Manufacturing Squares: An Integrative Statistical Process Control Exercise

    Science.gov (United States)

    Coy, Steven P.

    2016-01-01

    In the exercise, students in a junior-level operations management class are asked to manufacture a simple product. Given product specifications, they must design a production process, create roles and design jobs for each team member, and develop a statistical process control plan that efficiently and effectively controls quality during…

  18. Hybrid fuzzy/crisp-logic control of manufacturing systems

    OpenAIRE

    Porter, B; Moi, H.

    1996-01-01

    In recent years, techniques such as dynamic programming, the maximum principle, linear programming, and genetic algorithms have been used to synthesise optimal control policies for manufacturing systems. However, such techniques are frequently rather opaque and often yield control policies that are implemented by open-loop rather than closed-loop control systems. In this paper, it is therefore shown that closed-loop systems incorporating hybrid fuzzy/crisp-logic controllers can be readily des...

  19. Water Chemistry Control Technology to Improve the Performance of Nuclear Power Plants for Extended Fuel Cycles

    International Nuclear Information System (INIS)

    Ο To Develop the technology to manage the problems of AOA and radiation, corrosion as long term PWR operation. Ο To Establish the advanced water chemical operating systems. - Development of the proper water chemistry guidelines for long term PWR operation. AOA(Axial Offest Anomaly) has been reported in many PWR plants in the world, including Korea, especially in the plants of higher burn-up and longer cycle operation or power up-rate. A test loop has been designed and made by KAERI, in order to investigate and mitigate AOA problems in Korea. This project included the study of hydrodynamic simulation and the modeling about AOA. The analysis of radioactive crud was performed to investigate of NPPs primary water chemical effect on AOA and to reduce the radioactive dose rate. The high temperature measurement system was developed to on-line monitor of water chemistry in nuclear power plants. The effects of various environmental factors such as temperature, pressure, and flow rate on YSZ-based pH electrode were evaluated for ensuring the accuracy of high-temperature pH measurement. The inhibition technology for fouling and SCC of SG tube was evaluated to establish the water chemistry technology of corrosion control of nuclear system. The high temperature and high pressure crevice chemistry analysis test loop was manufactured to develop the water chemistry technology of crevice chemistry control

  20. Vibration control for precision manufacturing at Sandia National Laboratories

    International Nuclear Information System (INIS)

    Sandia National Laboratories performs R and D in structural dynamics and vibration suppression for precision applications in weapon systems, space, underwater, transportation and civil structures. Over the last decade these efforts have expanded into the areas of active vibration control and ''smart'' structures and material systems. In addition, Sandia has focused major resources towards technology to support weapon product development and agile manufacturing capability for defense and industrial applications. This paper will briefly describe the structural dynamics modeling and verification process currently in place at Sandia that supports vibration control and some specific applications of these techniques to manufacturing in the areas of lithography, machine tools and flexible robotics

  1. Wireless embedded control system for atomically precise manufacturing

    KAUST Repository

    Khan, Yasser

    2011-04-01

    This paper will explore the possibilities of implementing a wireless embedded control system for atomically precise manufacturing. The manufacturing process, similar to Scanning Tunneling Microscopy, takes place within an Ultra High Vacuum (UHV) chamber at a pressure of 10-10 torr. In order to create vibration isolation, and to keep internal noise to a minimum, a wireless link inside the UHV chamber becomes essential. We present a MATLAB simulation of the problem, and then demonstrate a hardware scheme between a Gumstix computer and a Linux based laptop for controlling nano-manipulators with three degrees of freedom. © 2011 IEEE.

  2. Statistical Data Mining for Efficient Quality Control in Manufacturing

    DEFF Research Database (Denmark)

    Khan, Abdul Rauf; Schiøler, Henrik; Knudsen, Torben Steen;

    2015-01-01

    process e.g sensor measurements, machine readings etc, and the major contributor of these big data sets are different quality control processes. In this article we will present methodology to extract valuable insight from manufacturing data. The proposed methodology is based on comparison of probabilities...

  3. Design, manufacturing and testing of Controllable Rubber Trailing Edge Flaps

    DEFF Research Database (Denmark)

    Løgstrup Andersen, Tom; Aagaard Madsen, Helge; Barlas, Thanasis K;

    The overall goal for the INDUFLAP project was realization of a test facility for development and test of Controllable Rubber Trailing Edge Flaps (CRTEF) for wind turbines. This report covers experimental work at DTU Wind Energy including design, manufacture and test of different configurations of...

  4. 76 FR 21917 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-04-19

    ... October 8, 2010, and published in the Federal Register on October 20, 2010, (75 FR 64744), Cayman Chemical... controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to manufacture small quantities of marihuana derivatives for research purposes. In reference to drug code...

  5. 75 FR 9614 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2010-03-03

    ... October 16, 2009, and published in the Federal Register on October 28, 2009, (74 FR 55587), Cayman... controlled substances listed in schedule I: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to manufacture small quantities of marihuana derivatives for research purposes....

  6. 76 FR 17968 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-03-31

    ... August 2, 2010, and published in the Federal Register on September 1, 2010, (75 FR 53720), Austin Pharma... controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I Alphamethadol (9605) I... code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol as a synthetic...

  7. 77 FR 2324 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2012-01-17

    ... August 9, 2011, and published in the Federal Register on August 18, 2011, 76 FR 51401, Austin Pharma LLC... controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to... drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol as a...

  8. The Intelligent Control Technology of Manufacturing Execution Process Based on RFID

    OpenAIRE

    Fan Ruicheng; Wang Aimin; Lv Yanpeng

    2015-01-01

    Intelligent manufacturing is an important trend in the development of the future manufacturing industry, and how to use the current technology to realize the existing traditional manufacturing mode change to the intelligent manufacturing mode need to be studied. Aimed at the implementation of the intelligent manufacturing mode, this paper proposed the intelligent manufacturing execution process control technology based on RFID. The framework of intelligent manufacturing execution process cont...

  9. EtoPlan: a concept for concurrent manufacturing planning and control - Building holarchies for manufacture-to-order environments

    OpenAIRE

    Giebels, Mark Mathieu Theodorus

    2000-01-01

    An essential demand for future manufacturing control systems is the ability to deal with the increased complexity due to a higher product variety, smaller batches and shorter throughput times. In particular for manufacture-to-order (i.e. make- or engineer-to-order) environments it is generally recognised that future manufacturing planning and control systems have to become more flexible and integrative compared to the currently existing systems. The versatility in order characteristics calls ...

  10. Water Chemistry Protection During AP1000 Secondary Equipment Manufacturing%AP1000二回路设备制造中的水化学防护

    Institute of Scientific and Technical Information of China (English)

    曾德军

    2015-01-01

    steam generator is one of the key equipment in AP1000 nuclear plant, by strictly control secondary Water quality, is of great significance in guaranteeing the structure integrity of steam generator heating tube, which can improve the service life of steam generator and make the system more safe and reliable operation. This paper lists the control factors of secondary water chemistry, and briefly introduced the Water Chemistry control countermeasures from material, manufacturing process and other aspects during AP1000 secondary equipments manufacturing process.%蒸汽发生器是AP1000核电站的关键设备之一,严格控制二回路水质,对确保蒸汽发生器换热管结构完整性,提高可靠性使用寿命,保障系统更安全可靠运行具有重要意义。本文简要列举了二回路水化学控制的相关因素,并从材料、制造工艺等方面对AP1000常规岛设备制造过程中的水化学防护措施进行了简要介绍。

  11. Double shell tanks (DST) chemistry control data quality objectives

    International Nuclear Information System (INIS)

    One of the main functions of the River Protection Project is to store the Hanford Site tank waste until the Waste Treatment Plant (WTP) is ready to receive and process the waste. Waste from the older single-shell tanks is being transferred to the newer double-shell tanks (DSTs). Therefore, the integrity of the DSTs must be maintained until the waste from all tanks has been retrieved and transferred to the WTP. To help maintain the integrity of the DSTs over the life of the project, specific chemistry limits have been established to control corrosion of the DSTs. These waste chemistry limits are presented in the Technical Safety Requirements (TSR) document HNF-SD-WM-TSR-006, Sec. 5.15, Rev 25 (CHG 2001). In order to control the chemistry in the DSTs, the Chemistry Control Program will require analyses of the tank waste. This document describes the Data Quality Objective (DQO) process undertaken to ensure appropriate data will be collected to control the waste chemistry in the DSTs

  12. Double shell tanks (DST) chemistry control data quality objectives

    International Nuclear Information System (INIS)

    One of the main functions of the River Protection Project is to store the Hanford Site tank waste until the Waste Treatment Plant (WTP) is ready to receive and process the waste. Waste from the older single-shell tanks is being transferred to the newer double-shell tanks (DSTs). Therefore, the integrity of the DSTs must be maintained until the waste from all tanks has been retrieved and transferred to the WTP. To help maintain the integrity of the DSTs over the life of the project, specific chemistry limits have been established to control corrosion of the DSTs. These waste chemistry limits are presented in the Technical Safety Requirements (TSR) document HNF-SD-WM-TSR-006, Sec. 5 . IS, Rev 2B (CHG 200 I). In order to control the chemistry in the DSTs, the Chemistry Control Program will require analyses of the tank waste. This document describes the Data Quality Objective (DUO) process undertaken to ensure appropriate data will be collected to control the waste chemistry in the DSTs. The DQO process was implemented in accordance with Data Quality Objectives for Sampling and Analyses, HNF-IP-0842, Rev. Ib, Vol. IV, Section 4.16, (Banning 2001) and the U.S. Environmental Protection Agency EPA QA/G4, Guidance for the Data Quality Objectives Process (EPA 1994), with some modifications to accommodate project or tank specific requirements and constraints

  13. Controlling high-throughput manufacturing at the nano-scale

    Science.gov (United States)

    Cooper, Khershed P.

    2013-09-01

    Interest in nano-scale manufacturing research and development is growing. The reason is to accelerate the translation of discoveries and inventions of nanoscience and nanotechnology into products that would benefit industry, economy and society. Ongoing research in nanomanufacturing is focused primarily on developing novel nanofabrication techniques for a variety of applications—materials, energy, electronics, photonics, biomedical, etc. Our goal is to foster the development of high-throughput methods of fabricating nano-enabled products. Large-area parallel processing and highspeed continuous processing are high-throughput means for mass production. An example of large-area processing is step-and-repeat nanoimprinting, by which nanostructures are reproduced again and again over a large area, such as a 12 in wafer. Roll-to-roll processing is an example of continuous processing, by which it is possible to print and imprint multi-level nanostructures and nanodevices on a moving flexible substrate. The big pay-off is high-volume production and low unit cost. However, the anticipated cost benefits can only be realized if the increased production rate is accompanied by high yields of high quality products. To ensure product quality, we need to design and construct manufacturing systems such that the processes can be closely monitored and controlled. One approach is to bring cyber-physical systems (CPS) concepts to nanomanufacturing. CPS involves the control of a physical system such as manufacturing through modeling, computation, communication and control. Such a closely coupled system will involve in-situ metrology and closed-loop control of the physical processes guided by physics-based models and driven by appropriate instrumentation, sensing and actuation. This paper will discuss these ideas in the context of controlling high-throughput manufacturing at the nano-scale.

  14. Optimal control in a failure prone manufacturing system

    OpenAIRE

    Xie, Xiaolan

    1989-01-01

    This paper addresses the optimal control in a failure prone manufacturing system. A discrete-time model is used. A single commodity is produced and there is a constant demand. The optimal control policy minimizes the long run average cost incurred by holding inventory and by failing to meet the demand. We show that the optimal control policy in any finite horizon problem is characterized by a critical number, which we call the ideal inventory level (or hedging point). The system should not pr...

  15. GREEN MANUFACTURING HELPS TO CONTROL GLOBAL WARMING: - A CRITICAL REVIEW

    Directory of Open Access Journals (Sweden)

    Shahzad Ahmad

    2015-02-01

    Full Text Available In this paper we are approaching to the effect of using Green manufacturing in the Global Warming. The main causes for energy inefficiency and environmental pollution are increased plant capacity and introduction of new factories, outdated production technology in use, aged industrial infrastructures, lack of management skills and coal dominated energy structures. Therefore, there is a need for an integrated approach like Green Manufacturing technology towards energy and environment management of the industry so that better energy efficiency and environmental friendliness can be achieved. This research work provides information on control techniques and measures that are available and adopted by steel industries to moderate greenhouse gas (GHG emissions, global warming, reduced CO2 emission, describes the process technology in use, energy saving opportunities, Environmental benefits of recycling & Sustainable development related to the iron and steel manufacturing sector through green manufacturing technology. We introduce the Indian iron and steel industry in more detail taking into account industry, production, technologies, energy consumption within processes, environmental impacts of steel recycling etc.

  16. Manufacturing of High Quality Teachers for Chemistry Education at Higher Secondary Level in Current Era

    Directory of Open Access Journals (Sweden)

    *R. Azmat

    2013-09-01

    Full Text Available Education is the most influential tool whose efficient use requires the power of determination, devoted work and sacrifice. As teachers are major handler of this tool therefore, they must possess qualities of high education and competency for deliver. Education extends attractive way of life, talent and manners which make an individual a fine civilian. Primary and secondary education is one of the foundation stone of development of children and country. It acts as a vital part in placing the proper institution of child’s cultural, social, moral, emotional, intellectual, physical and spiritual improvement. Primary education contributes to national development while education at post graduate level provides think tank for progress of country. The Secondary education which serves as a link among primary and higher education is expected to prepare young people between the age group of 14-18 in the world of work, who are ready to enter into advanced education. Chemistry is the basis of life, and subject of importance in nation building, acquiring much attention from the world class Universities now days, to build interest and skills into the students for complex education. Chemical education is an active area of research within both the disciplines of chemistry and education, focusing on learning and teaching of chemistry in schools, colleges and universities, with the goals of understanding how students learn chemistry, how best to teach chemistry. The curricula of higher secondary education require special attention at theory and practical level which should build the interest and attraction in chemistry in the age of 14-18. There is need of designing new curricula, covering chemistry in an easiest and attractive way associated with the environment1. Organization of continual workshops for teachers for fresh up courses aimed at building awareness in new themes in chemistry education. Themes1,2 in chemistry education should consist of

  17. The geometric phase controls ultracold chemistry

    International Nuclear Information System (INIS)

    In this study, the geometric phase is shown to control the outcome of an ultracold chemical reaction. The control is a direct consequence of the sign change on the interference term between two scattering pathways (direct and looping), which contribute to the reactive collision process in the presence of a conical intersection (point of degeneracy between two Born-Oppenheimer electronic potential energy surfaces). The unique properties of the ultracold energy regime lead to an effective quantization of the scattering phase shift enabling maximum constructive or destructive interference between the two pathways. By taking the O + OH → H + O2 reaction as an illustrative example, it is shown that inclusion of the geometric phase modifies ultracold reaction rates by nearly two orders of magnitude. Interesting experimental control possibilities include the application of external electric and magnetic fields that might be used to exploit the geometric phase effect reported here and experimentally switch on or off the reactivity

  18. Cavity-Controlled Chemistry in Molecular Ensembles

    Science.gov (United States)

    Herrera, Felipe; Spano, Frank C.

    2016-06-01

    The demonstration of strong and ultrastrong coupling regimes of cavity QED with polyatomic molecules has opened new routes to control chemical dynamics at the nanoscale. We show that strong resonant coupling of a cavity field with an electronic transition can effectively decouple collective electronic and nuclear degrees of freedom in a disordered molecular ensemble, even for molecules with high-frequency quantum vibrational modes having strong electron-vibration interactions. This type of polaron decoupling can be used to control chemical reactions. We show that the rate of electron transfer reactions in a cavity can be orders of magnitude larger than in free space for a wide class of organic molecular species.

  19. Cavity-controlled chemistry in molecular ensembles

    CERN Document Server

    Herrera, Felipe

    2015-01-01

    The demonstration of strong and ultrastrong coupling regimes of cavity QED with polyatomic molecules has opened new routes to control chemical dynamics at the nanoscale. We show that strong resonant coupling of a cavity field with an electronic transition can effectively decouple collective electronic and nuclear degrees of freedom in a disordered molecular ensemble, even for molecules with high-frequency quantum vibrational modes having strong electron-vibration interactions. This type of polaron decoupling can be used to control chemical reactions. We show that the rate of electron transfer reactions in a cavity can be orders of magnitude larger than in free space, for a wide class of organic molecular species.

  20. Analytical chemistry measurements quality control program using computer applications

    International Nuclear Information System (INIS)

    An Analytical Chemistry Measurements Quality Control Program assures the reliability of analytical measurements performed at the Barnwell Nuclear Fuel Plant. The program includes training, methods quality control, replicate samples and measurements, mass measurements, interlaboratory sample exchanges, and standards preparation. This program has been designed to meet the requirements of 10CFR70.57. Portions of the program have been automated by using a PDP 11/35 computer system to provide features which are not readily available in manual systems. These include such items as realtime measurement control, computer calculated bias and precision estimates, various surveillance applications, and evaluation of measurement system variables. The efficiency of the computer system has been demonstrated in gathering and assimilating the results of over 1100 quality control samples during a recent cold chemical checkout campaign. These data were used to determine equations for predicting measurements reliability estimates; to evaluate measurement performance of the analysts, equipment, and measurement period; and to provide directions for chemistry methods modifications and additional training requirements. A procedure of replicate sampling and measuring provides random error estimates. The analytical chemistry measurement quality control activities during the campaign represented about 10% of the total analytical chemistry effort

  1. Controlling Chemistry in Dynamic Nanoscale Systems

    DEFF Research Database (Denmark)

    Jesorka, Aldo; Lizana, Ludvig; Konkoli, Zoran;

    2011-01-01

    Spatial organization and shape dynamics are inherent properties of biological cells and cell interiors. There are strong indications that these features are important for the in vivo control of reaction parameters in biochemical transformations. Nanofluidic model devices founded on surfactant sys...

  2. Optimized continuous pharmaceutical manufacturing via model-predictive control.

    Science.gov (United States)

    Rehrl, Jakob; Kruisz, Julia; Sacher, Stephan; Khinast, Johannes; Horn, Martin

    2016-08-20

    This paper demonstrates the application of model-predictive control to a feeding blending unit used in continuous pharmaceutical manufacturing. The goal of this contribution is, on the one hand, to highlight the advantages of the proposed concept compared to conventional PI-controllers, and, on the other hand, to present a step-by-step guide for controller synthesis. The derivation of the required mathematical plant model is given in detail and all the steps required to develop a model-predictive controller are shown. Compared to conventional concepts, the proposed approach allows to conveniently consider constraints (e.g. mass hold-up in the blender) and offers a straightforward, easy to tune controller setup. The concept is implemented in a simulation environment. In order to realize it on a real system, additional aspects (e.g., state estimation, measurement equipment) will have to be investigated. PMID:27317987

  3. Control through operators for quantum chemistry

    CERN Document Server

    Laurent, Philippe; Salomon, Julien; Turinici, Gabriel

    2012-01-01

    We consider the problem of operator identification in quantum control. The free Hamiltonian and the dipole moment are searched such that a given target state is reached at a given time. A local existence result is obtained. As a by-product, our works reveals necessary conditions on the laser field to make the identification feasible. In the last part of this work, some algorithms are proposed to compute effectively these operators.

  4. Development of a Reconfigurable Platform for Manufacturing Equipment Control

    Institute of Scientific and Technical Information of China (English)

    FENG Shouting; LI Di; CHENG Xiangyu

    2006-01-01

    In modern manufacturing equipment control area, controller is required to deliver higher computing capability for adopting advanced algorithms to meet speed and accuracy requirements, and reconfigurabilities for changing or (and) adding features or functions. This paper presents a methodology in design and implementation of a high performance and reconfigurable platform for manufacturing equipment control. This methodology is in virtue of system on a programmable chip (SoPC) technology but replacing the on-chip processor by an external high performance, floating-point digital signal processor (DSP). The application of the DSP is designed as a multi-threaded framework, which has more flexibilities than a traditional single-loop one. Furthermore, the field programmable gate array (FPGA) system can be reconfigured easily and quickly to meet a new requirement by dragging and dropping pre-built components in a SoPC building environment. As a result, the controller platform is more reconfigurable in terms of algorithms and functions. This platform is implemented in a 3-axis milling machine control and the result indicates that the design and implementation presented in this paper is feasible.

  5. Service Orientation in Holonic and Multi-Agent Manufacturing Control

    CERN Document Server

    Thomas, André; Trentesaux, Damien

    2012-01-01

    Service orientation is emerging nowadays at multiple organizational levels in enterprise business, and it leverages technology in response to the growing need for greater business integration, flexibility and agility of manufacturing enterprises. This book gathers contributions from scientists, researchers and industrialists on concepts, methods, frameworks and implementing issues addressing trends in the service orientation of control technology and management applied to manufacturing enterprise. It analyzes a Service Oriented Architecture (SOA) representing a technical architecture, a business modelling concept, a type of infrastructure, an integration source and a new way of viewing units of automation within the enterprise. The presents how SOA aligns the business world with the world of information technology in a way that makes both more effective.  

  6. New Interference Mechanism Controls Ultracold Chemistry

    Science.gov (United States)

    Kendrick, Brian K.; Hazra, Jisha; Balakrishnan, N.

    2016-05-01

    A newly discovered interference mechanism has been shown to control the outcome of ultracold chemical reactions. The mechanism originates from the unique properties associated with ultracold collisions, namely: (1) isotropic (s-wave) scattering and (2) an effective quantization of the scattering phase shift (which originates from the bound state structure of the molecule). These two properties can lead to maximum constructive or destructive interference between two interfering reaction pathways (such as exchange and non-exchange in systems with two or more identical nuclei). If the molecular system exhibits a conical intersection, then the associated geometric phase is shown to act as a ``quantum switch'' which can turn the reactivity on or off. Reaction rate coefficients for the O + OH --> H + O2 and H + H2, reactions are presented which explicitly demonstrate the effect. Experimentalists might exploit this new mechanism to control ultracold reactions by the application of external electric or magnetic fields or by the selection of a particular nuclear spin state. This work was supported in part by the LDRD program (Grant No. 20140309ER) at LANL (B.K.) and by NSF Grant PHY-1505557 (N.B.) and ARO MURI Grant No. W911NF-12-1-0476 (N.B.).

  7. Spectrophotometric Procedure for Fast Reactor Advanced Coolant Manufacture Control

    Science.gov (United States)

    Andrienko, O. S.; Egorov, N. B.; Zherin, I. I.; Indyk, D. V.

    2016-01-01

    The paper describes a spectrophotometric procedure for fast reactor advanced coolant manufacture control. The molar absorption coefficient of dimethyllead dibromide with dithizone was defined as equal to 68864 ± 795 l·mole-1·cm-1, limit of detection as equal to 0.583 · 10-6 g/ml. The spectrophotometric procedure application range was found to be equal to 37.88 - 196.3 g. of dimethyllead dibromide in the sample. The procedure was used within the framework of the development of the method of synthesis of the advanced coolant for fast reactors.

  8. Control and Plant Modeling for Manufacturing Systems using Basic Statecharts

    OpenAIRE

    Moura, Raimundo; Guedes, Luiz Affonso

    2010-01-01

    In this work we presented a methodology for systematizing the process of plant and control modeling of manufacturing systems. Our proposal uses a formalism based on Statecharts diagrams, called Basic Statecharts (BSC). The plant modeling has three phases which can be executed as many times as necessary. In general, this methodology represents a hybrid approach - bottom-up and top-down, allowing components reuse and keeping a one-to-one relation between plant and model (i.e., it is faithful to...

  9. Additive Manufacturing: Multi Material Processing and Part Quality Control

    OpenAIRE

    Pedersen, David Bue; De Chiffre, Leonardo; Hansen, Hans Nørgaard

    2013-01-01

    Denne Ph.D afhandling,?Additive Manufacturing: Multi Material Processing and Part Quality Control?, omhandler additive fremstillingsmetoder, hvilket er en familie af processer der er kendetegnet ved at de er computerstyret, de drager nytte af en høj grad af automation, og de fremstiller emner lagvis ved addition af materiale. To områder af særlig interesse er addreseret i denne afhandling. De er begge forankret i to meget forskellige områder, men tjener fælles formål. At styrke additive frems...

  10. The operation of large computer-controlled manufacturing systems

    Energy Technology Data Exchange (ETDEWEB)

    Upton, D.M.

    1988-01-01

    This work examines methods for operation of large computer-controlled manufacturing systems, with more than 50 or so disparate CNC machines in congregation. The central theme is the development of a distributed control system, which requires minimal central supervision, and allows manufacturing system re-configuration without extensive control software re-writes. Provision is made for machines to learn from their experience and provide estimates of the time necessary to effect various tasks. Routing is opportunistic, with varying degrees of myopia depending on the prevailing situation. Necessary curtailments of opportunism are built in to the system, in order to provide a society of machines that operate in unison rather than in chaos. Negotiation and contention resolution are carried out using a UHF radio communications network, along with processing capability on both pallets and tools. Graceful and robust error recovery is facilitated by ensuring adequate pessimistic consideration of failure modes at each stage in the scheme. Theoretical models are developed and an examination is made of fundamental characteristics of auction-based scheduling methods.

  11. Cernavoda NPP - Boiler and steam cycle chemistry control

    International Nuclear Information System (INIS)

    Steam generators protection against corrosion and fouling is an ongoing issue for nuclear power plants. The true effectiveness of the secondary chemistry control program is best judged by the absence of secondary side corrosion related tube degradation particularly that leads to tube plugging or sleeving or tube support degradation. To continue striving for excellence in chemical control, the following issues should be considered: Continuous evaluation of the effectiveness of the chemistry control program in mitigating SG damage; Evaluation of plant compliance with the program; Laboratory quality assurance program to assure that laboratory analyses are accurate and reproductibile; Quality assurance program for on-line monitoring equipment to assure that results from this equipment are accurate. (R.P.)

  12. SENSOR FUSION CONTROL SYSTEM FOR COMPUTER INTEGRATED MANUFACTURING

    Directory of Open Access Journals (Sweden)

    C.M. Kumile

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT: Manufacturing companies of today face unpredictable, high frequency market changes driven by global competition. To stay competitive, these companies must have the characteristics of cost-effective rapid response to the market needs. As an engineering discipline, mechatronics strives to integrate mechanical, electronic, and computer systems optimally in order to create high precision products and manufacturing processes. This paper presents a methodology of increasing flexibility and reusability of a generic computer integrated manufacturing (CIM cell-control system using simulation and modelling of mechatronic sensory system (MSS concepts. The utilisation of sensors within the CIM cell is highlighted specifically for data acquisition, analysis, and multi-sensor data fusion. Thus the designed reference architecture provides comprehensive insight for the functions and methodologies of a generic shop-floor control system (SFCS, which consequently enables the rapid deployment of a flexible system.

    AFRIKAANSE OPSOMMING: Hedendaagse vervaardigingsondernemings ervaar gereeld onvoorspelbare markveranderinge wat aangedryf word deur wêreldwye mededinging. Om kompeterend te bly moet hierdie ondernemings die eienskappe van kosteeffektiwiteit en snelle-respons op markfluktuasies toon. Megatronika streef daarna om meganiese, elektroniese en rekenaarstelsels optimaal te integreer om hoëpresisieprodukte en produksieprosesse daar te stel. Hierdie artikel suggereer 'n metodologie vir toenemende aanpasbaarheid en herbruikbaarheid van 'n generiese rekenaargeïntegreerde vervaardigingsel-beheersisteem deur die gebruik van simulasie en die modellering van megatroniese sensorsisteemkonsepte. Die aanwending van sensors binne die sel fasiliteer datavaslegging, ontleding en multisensordatafusie. Sodoende verskaf die ontwerpte argitektuur insig in die funksie en metodologie van 'n generiese stukwerkwinkelbeheersisteem wat die vinnige

  13. Vibration control for precision manufacturing using piezoelectric actuators

    Energy Technology Data Exchange (ETDEWEB)

    Martinez, D.R.; Hinnerichs, T.D.; Redmond, J.M.

    1995-12-31

    Piezoelectric actuators provide high frequency, force, and stiffness capabilities along with reasonable Stroke limits, all of which can be used to increase performance levels in precision manufacturing systems. This paper describes two examples of embedding piezoelectric actuators in structural components for vibration control. One example involves suppressing the self excited chatter phenomenon in the metal cutting process of a milling machine and the other involves damping vibrations induced by rigid body stepping of a photolithography platen. Finite element modeling and analyses are essential for locating and sizing the actuators and permit further simulation studies of the response of the dynamic system. Experimental results are given for embedding piezoelectric actuators in a cantilevered bar configuration, which was used as a surrogate machine tool structure. These results are incorporated into a previously developed milling process simulation and the effect of the control on the cutting process stability diagram is quantified. Experimental results are also given for embedding three piezoelectric actuators in a surrogate photolithography platen to suppress vibrations. These results demonstrate the potential benefit that can be realized by applying advances from the field of adaptive structures to problems in precision manufacturing.

  14. RECONFIGURABLE PRODUCT ROUTING AND CONTROL FOR MASS CUSTOMISATION MANUFACTURING

    Directory of Open Access Journals (Sweden)

    A. J. Walker

    2012-01-01

    Full Text Available

    ENGLISH ABSTRACT:Reconfigurable control of flexible manufacturing systems can allow for the efficient and responsive production of customised product instances. This can aid in providing make-to-order business models for various small- to medium-sized enterprises in South Africa, and provide competitive advantage in a dynamic global marketplace. Reconfigurable control application requires an understanding of the modes of production variability in mass customisation manufacturing. Temporally uncorrelated workflow routings are considered as one of these production variability modes. In this light, this paper addresses the flexible material payload routing problem, and presents a mobile robot platform that has been developed to research and design reconfigurable routing systems.

    AFRIKAANSE OPSOMMING:Verstelbare beheer van aanpasbare vervaardigingstelsels kan die doeltreffende en reaktiewe produksie van doelgemaakte produkeksemplare toelaat. Hierdie beheer kan assisteer in die voorsiening van vervaardig-na-bestellingbesigheidsmodelle aan ’n aantal klein- tot medium-grootte ondernemings in Suid-Afrika, en aan hulle ’n kompeterende voorsprong bied in ’n dinamiese globale mark. Die instelling van verstelbare beheer vereis dat die modi van produkveranderlikheid in massa verbruikersaanpassingsvervaardiging verstaan word. Hierdie artikel spreek die probleem van aanpasbare roetebepaling van materiaalvragte in massa verbruikersaanpassingsvervaardiging aan. ’n Mobiele robot-platform, ontwikkel vir navorsing in verstelbare roetebepalingstelsels, word ook voorgelê.

  15. Chemistry control strategies for a supercritical water-cooled reactor

    International Nuclear Information System (INIS)

    The long-term viability of any Generation IV Supercritical Water-cooled Reactor (SCWR) concept depends on the ability of reactor designers and operators to predict and control water chemistry to minimize corrosion and corrosion product transport. Currently, SCWR material testing is being carried out using a limited range of water chemistries to establish the dependencies of the corrosion behavior on parameters such as water temperature and dissolved oxygen concentration. Once a final suite of candidate alloys is identified, more detailed, longer term testing will be needed under water chemistry regimes expected to be used in the SCWR. Prior to these tests, it will be necessary to identify proposed water chemistry regimes for the SCWR, and provide expected ranges for the key parameters. The direct-cycle design proposed for various SCWR concepts take advantage of the extensive operating experience world-wide of fossil-fired SCW power plants. Conceptually, the SCWR replaces the fossil-fired boiler with the reactor core (pressure vessel or pressure tube); the concept is broadly similar to that of a boiling water reactor. Current fossil-fired SCW power plants use either an all-volatile treatment or oxygenated water treatment for the feedwater systems. While the optimal water chemistry for a SCWR is yet to be determined, the monitored parameters are likely to be the same as those in existing fossil-fired and nuclear power plants: pH; conductivity, and concentrations of O2, H2, additives, impurities, corrosion and activation products. Monitoring will be required at many of the same components: feedwater, main 'steam', drains, pump outlets, condenser hotwell, and purification inlets and outlets. This paper outlines the strategy being used to develop a water chemistry regime for a CANDU® SCWR. It describes the key areas identified for chemistry monitoring and control: a) the reactor core, where materials are subjected to irradiation and high temperature, b

  16. Strategy For Yield Control And Enhancement In VLSI Wafer Manufacturing

    Science.gov (United States)

    Neilson, B.; Rickey, D.; Bane, R. P.

    1988-01-01

    In most fully utilized integrated circuit (IC) production facilities, profit is very closely linked with yield. In even the most controlled manufacturing environments, defects due to foreign material are a still major contributor to yield loss. Ideally, an IC manufacturer will have ample engineering resources to address any problem that arises. In the real world, staffing limitations require that some tasks must be left undone and potential benefits left unrealized. Therefore, it is important to prioritize problems in a manner that will give the maximum benefit to the manufacturer. When offered a smorgasbord of problems to solve, most people (engineers included) will start with what is most interesting or the most comfortable to work on. By providing a system that accurately predicts the impact of a wide variety of defect types, a rational method of prioritizing engineering effort can be made. To that effect, a program was developed to determine and rank the major yield detractors in a mixed analog/digital FET manufacturing line. The two classical methods of determining yield detractors are chip failure analysis and defect monitoring on drop in test die. Both of these methods have short comings: 1) Chip failure analysis is painstaking and very time consuming. As a result, the sample size is very small. 2) Drop in test die are usually designed for device parametric analysis rather than defect analysis. To provide enough wafer real estate to do meaningful defect analysis would render the wafer worthless for production. To avoid these problems, a defect monitor was designed that provided enough area to detect defects at the same rate or better than the NMOS product die whose yield was to be optimized. The defect monitor was comprehensive and electrically testable using such equipment as the Prometrix LM25 and other digital testers. This enabled the quick accumulation of data which could be handled statistically and mapped individually. By scaling the defect densities

  17. Improved primary water chemistry control of PWR plant in Japan

    International Nuclear Information System (INIS)

    Elevated pH operation to the pH value of 7.3 at 285degC is known to be effective for the reduction of radiation source in the primary water system of PWRs. A research project was started in 1989 and concluded in 1996 to study and verify the optimum pH and/or Li concentration from the viewpoint of radiation source reduction and materials integrity under improved water chemistry. This research project is sponsored by the Ministry of International Trade and Industries (MITI) in Japan and has two programs; high pH and high Li. The high Li program was conducted to establish the optimum Li concentration for the high boron concentration region (1100 - 1800 ppm) of the high burn up operation. In this paper, we shall discuss radiation source behavior under high pH conditions and PWSCC (Primary Water Stress Corrosion Cracking) susceptibility of materials with change of primary water chemistry conditions and the improved water chemistry control based on these tests results. (author)

  18. Management and Control of Outsourcing in Dispersed Network Manufacturing Systems

    Institute of Scientific and Technical Information of China (English)

    Rob; Dekkers; Luping; Wang

    2002-01-01

    The trend of economic globalisation and advances in i nformation technology has led to the emergence of dispersed manufacturing system s as a form of the virtual organisation. New manufacturing strategy pays more at tention to the management of the total value chain and therefore puts emphasis o n outsourcing. In fact, outsourcing is an efficient way of utilizing available r esources and has become one key aspect of the manufacturing strategy. Improved d ecision and organization on outsourcing will result ...

  19. Cocrystal Controlled Solid-State Synthesis: A Green Chemistry Experiment for Undergraduate Organic Chemistry

    Science.gov (United States)

    Cheney, Miranda L.; Zaworotko, Michael J.; Beaton, Steve; Singer, Robert D.

    2008-01-01

    Green chemistry has become an important area of concern for all chemists from practitioners in the pharmaceutical industry to professors and the students they teach and is now being incorporated into lectures of general and organic chemistry courses. However, there are relatively few green chemistry experiments that are easily incorporated into…

  20. Object-oriented architecture of control system for agile manufacturing cells

    OpenAIRE

    Lau, HCW; Ning, A.; Chan, FTS; Zhang, J.

    2000-01-01

    The depiction of the agile manufacturing cell includes a synopsis of some of the change proficiencies obtained by the configuration. To achieve agile configuration, the cell control system for agile manufacturing must be rapidly and efficiently generated or modified. In this paper, the object-oriented architecture is defined that supports design and implementation of highly reconfigurable control systems for agile manufacturing cells, which is composed of database objects, control objects, an...

  1. 76 FR 39127 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-07-05

    ...). Marihuana (7360) I Tetrahydrocannabinols (7370) I 3,4,5-Trimethoxyamphetamine (7390) I 4-Bromo-2,5... plans to manufacture small quantities of marihuana derivatives for research purposes. In reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidol. In reference to drug...

  2. New Concepts and Theories For Intelligent Control of Cellular Manufacturing Systems

    DEFF Research Database (Denmark)

    Langer, Gilad

    1996-01-01

    evolve around the idea of integrating intelligent elements into the control systems of the manufacturing systems. The research will concentrate on integration of manufacturing units by use of intelligent control mechanisms, information technology and the material handling as the key integrators.......This paper will present some new theories such as biological manufacturing system, the fractal factory theory, holonic manufacturing systems, and multi-agent theory in the context of manufacturing systems. The objective of the paper is to show how these theories can contribute to develop the new...... concepts that are required for controlling the manufacturing systems of the future. Thereafter it will present the potential for improvement of the manufacturing system by introduction and implementation of these theories. The paper tries to encapsulate the main area of my Ph.D. thesis research which will...

  3. Chemistry

    International Nuclear Information System (INIS)

    The chemical research and development efforts related to the design and ultimate operation of molten-salt breeder reactor systems are concentrated on fuel- and coolant-salt chemistry, including the development of analytical methods for use in these systems. The chemistry of tellurium in fuel salt is being studied to help elucidate the role of this element in the intergranular cracking of Hastelloy N. Studies were continued of the effect of oxygen-containing species on the equilibrium between dissolved UF3 and dissolved UF4, and, in some cases, between the dissolved uranium fluorides and graphite, and the UC2. Several aspects of coolant-salt chemistry are under investigation. Hydroxy and oxy compounds that could be formed in molten NaBF4 are being synthesized and characterized. Studies of the chemistry of chromium (III) compounds in fluoroborate melts were continued as part of a systematic investigation of the corrosion of structural alloys by coolant salt. An in-line voltammetric method for determining U4+/U3+ ratios in fuel salt was tested in a forced-convection loop over a six-month period. (LK)

  4. Water chemistry control practices and data of the European BWR fleet

    International Nuclear Information System (INIS)

    Nineteen BWR plants are in operation in Europe, nine built by ASEA Atom, six by Siemens KWU and four by General Electric. This paper gives an overview of water chemistry operation practices and parameters of the European BWR plants. General design characteristics of the plants are described. Chemistry control strategies and underlying water chemistry guidelines are summarized. Chemistry data are presented and discussed with regard to plant design characteristics. The paper is based on a contract of the European BWR Forum with AREVA on a chemistry sourcebook for member plants. The survey of chemistry data was conducted for the years 2002 to 2008. (author)

  5. 77 FR 5848 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2012-02-06

    ... October 20, 2011, and published in the Federal Register on October 28, 2011, 76 FR 66994, Research... Marihuana (7360) I Cocaine (9041) II The Institute will manufacture marihuana, and cocaine derivatives...

  6. GREEN MANUFACTURING HELPS TO CONTROL GLOBAL WARMING: - A CRITICAL REVIEW

    OpenAIRE

    Shahzad Ahmad; Tasmeem Ahmad Khan

    2015-01-01

    In this paper we are approaching to the effect of using Green manufacturing in the Global Warming. The main causes for energy inefficiency and environmental pollution are increased plant capacity and introduction of new factories, outdated production technology in use, aged industrial infrastructures, lack of management skills and coal dominated energy structures. Therefore, there is a need for an integrated approach like Green Manufacturing technology towards energy and environme...

  7. On-line chemistry control in EDF Nuclear Power Plants

    International Nuclear Information System (INIS)

    The document describes Electricite De France (EDF) policy concerning chemistry control in Nuclear Power Plants (NPP). Due to the great importance of some parameters, and high risks of pollution of grab samples, the main parameters are continuously measured by reliable chemical on-line monitors. EDF has consequently developed a large program of tests to select the best instrument, in a specific facility installed in a NPP. In addition, a guideline document describes all the operations necessary for the correct use of all chemical monitors. Periodic evaluations are organized to ensure the good quality of in-plant measurements: they consist of a complete inspection of all the monitors implemented in the unit, and comparative measurements between the unit monitors and those of Groupe des Laboratories (GDL), the central laboratories of EDF. EDF is presently designing chemical expert systems, making it possible to improve reliability and to shorten response time for all operation phases. The main advantage expected is an improvement of chemistry quality in the plants, resulting from quicker operator reaction in case of abnormal situations

  8. A Service-Oriented and Holonic Control Architecture to the Reconfiguration of Dispersed Manufacturing Systems

    OpenAIRE

    Silva, Robson,; Blos, Mauricio,; Junqueira, Fabrício; Santos Filho, Diolino,; Miyagi, Paulo,

    2014-01-01

    Part 5: Monitoring and Supervision Systems International audience Manufacturing control systems must quickly react to variations of product, process specifications, fault occurrence, changes in the resources functional capabilities, and other operational demands. Besides, to gain competitive advantages, dispersed manufacturing systems must cooperate with each other. The combination of holonic control system and service-oriented architecture techniques can be effective to integrate these...

  9. Research on Technological Process Control Model of Reverse Logistics in Manufacturing System

    Institute of Scientific and Technical Information of China (English)

    CHANG Jiane; LIU Chao

    2006-01-01

    This paper has found out some important input factors of reverse logistics in manufacturing system throuth analysis and summary, and established four kinds of technological process control models of reverse logistics in manufacturing system according to different processing methods. These models embed each other that form a cubic control system of reverse logistics.

  10. 14 CFR 21.143 - Quality control data requirements; prime manufacturer.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Quality control data requirements; prime manufacturer. 21.143 Section 21.143 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... control data requirements; prime manufacturer. (a) Each applicant must submit, for approval,...

  11. Surface chemistry interventions to control boiler tube fouling - Part II

    International Nuclear Information System (INIS)

    This is the third in a series of reports from an investigation co-funded by the Electric Power Research Institute (EPRI) and by Atomic Energy of Canada Limited (AECL) into the effectiveness of alternative amines for controlling the rate of tube-bundle fouling under steam generator (SG) operating conditions. The objectives of this investigation are to determine whether the fouling rate depends on the amine used for pH control, to identify those factors that influence the effectiveness, and use this information to optimize the selection of an amine for chemistry control and deposit control in the steam cycle and steam generator, respectively. Work to date has demonstrated that the rate of particle deposition under steam generator operating conditions is strongly influenced by surface chemistry (Turner et al., 1997; Turner et al., 1999). This dependence upon surface chemistry is illustrated by the difference between the deposition rates measured for hematite and magnetite, and by the dependence of the particle deposition rate on the amine used for pH control. Deposition rates of hematite were found to be more than 10 times greater than those for magnetite under similar test conditions (Turner et al., 1997). At 270oC and pHT 6.2, the surfaces of hematite and magnetite are predicted to be positively charged and negatively charged, respectively (Shoonen, 1994). Measurements of the point of zero charge (PZC) of magnetite at temperatures from 25oC to 290oC by Wesolowski et al. (1999) have confirmed that magnetite is negatively charged at the stated conditions. A PZC of 4.2 was measured for Alloy 600 at 25oC (Balakrishnan and Turner, un-published results), and its surface is expected to remain negatively charged for alkaline chemistry over the temperature range of interest. Therefore, there will be a repulsive force between the surfaces of magnetite particles and Alloy 600 at 270oC and pHT 6.2 that is absent for hematite particles depositing under the same conditions. This

  12. Management control of supplier relationships in manufacturing: a case study in the automotive industry.

    OpenAIRE

    Pernot, Eli; Roodhooft, Filip

    2008-01-01

    This paper studies management control design of supplier relationships in manufacturing, a supply chain phase currently under-explored. Compared to supplier relations during procurement and R&D, which research found to be governed by a combination of formal and informal controls, supplier relations in manufacturing are more formal, so that they could be governed by more formal and less informal controls. To refine the management control system and influencing contingencies, we pro...

  13. Chemistry

    International Nuclear Information System (INIS)

    Research progress is reported in programs on fuel-salt chemistry, properties of compounds in the Li--Te system, Te spectroscopy UF4--H equilibria, porous electrode studies of molten salts, fuel salt-coolant salt reactions, thermodynamic properties of transition-metal fluorides, and properties of sodium fluoroborate. Developmental work on analytical methods is summarized including in-line analysis of molten MSBR fuel, analysis of coolant-salts for tritium, analysis of molten LiF--BeF2--ThF4 for Fe and analysis of LiF--BeF--ThF4 for Te

  14. Controlled Chemistry Approach to the Oxo-Functionalization of Graphene.

    Science.gov (United States)

    Eigler, Siegfried

    2016-05-17

    Graphene is the best-studied 2D material available. However, its production is still challenging and the quality depends on the preparation procedure. Now, more than a decade after the outstanding experiments conducted on graphene, the most successful wet-chemical approach to graphene and functionalized graphene is based on the oxidation of graphite. Graphene oxide has been known for more than a century; however, the structure bears variable large amounts of lattice defects that render the development of a controlled chemistry impossible. The controlled oxo-functionalization of graphene avoids the formation of defects within the σ-framework of carbon atoms, making the synthesis of specific molecular architectures possible. The scope of this review is to introduce the field of oxo-functionalizing graphene. In particular, the differences between GO and oxo-functionalized graphene are described in detail. Moreover analytical methods that allow determining lattice defects and functional groups are introduced followed by summarizing the current state of controlled oxo-functionalization of graphene. PMID:26990805

  15. Automation in Siemens fuel manufacturing - the basis for quality improvement by statistical process control (SPC)

    International Nuclear Information System (INIS)

    Statistical Process Control (SPC) is one of the systematic tools to perform a valuable contribution to the control and planning activities for manufacturing processes and product quality. Advanced Nuclear Fuels GmbH (ANF) started a program to introduce SPC in all sections of the manufacturing process of fuel assemblies. The concept phase is based on a realization of SPC in 3 pilot projects. The existing manufacturing devices are reviewed for the utilization of SPC. Subsequent modifications were made to provide the necessary interfaces. The processes 'powder/pellet manufacturing'. 'cladding tube manufacturing' and 'laser-welding of spacers' are located at the different locations of ANF. Due to the completion of the first steps and the experience obtained by the pilot projects, the introduction program for SPC has already been extended to other manufacturing processes. (authors)

  16. New Concepts and Theories For Intelligent Control of Cellular Manufacturing Systems

    DEFF Research Database (Denmark)

    Langer, Gilad

    1996-01-01

    This paper will present some new theories such as biological manufacturing system, the fractal factory theory, holonic manufacturing systems, agile manufacturing, object orientation, multi-agent theory, artificial intelligence, and artificial life in the context of manufacturing systems....... The paper tries to encapsulate the main area of my Ph.D. thesis research which will evolve around the idea of integrating intelligent elements into the control systems of the manufacturing systems. Furthermore it intends to show how the curriculum and discussions of the IPS Ph.D. course will and have...... contributed to my research. The research will concentrate on integration of manufacturing units by use of intelligent control mechanisms, information technology and the material handling as the key integrators....

  17. 75 FR 6062 - Manufacturer of Controlled Substances Notice of Registration

    Science.gov (United States)

    2010-02-05

    ... 21, 2009, and published in the Federal Register on September 8, 2009, (74 FR 46232), Research... schedules I and II: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I Cocaine (9041) I The Institute will manufacture small quantities of cocaine and marihuana derivatives for use by their...

  18. Corrosion rate reduction by chemistry control during Hot Functional Test

    International Nuclear Information System (INIS)

    It is important to minimize a generation of radioactive corrosion products which become a radiation source, in order to reduce the radiation exposure in light water reactor. Therefore, as a countermeasure of radiation source reduction during plant commissioning, it has been studied to form more stable protective film by a improvement of water chemistry during Hot Functional Test (HFT). Consequently, it was confirmed that hydrogen (H2)+LiOH addition chemistry was more effective as a water chemistry for HFT. This new water chemistry for HFT was applied at Tomari No. 1, new constructed plant. The radiation level in Tomari No. 1 at 1st. annual inspection trended to be lower than that of plants with conventional water chemistry during HFT. It is considered that the new HFT water chemistry leads to radiation exposure reduction. (author)

  19. Integration of Scheduling and Advanced Process Control in Semiconductor Manufacturing: Review and Outlook

    OpenAIRE

    Yugma, Claude; Blue, Jakey; DAUZERE-PERES, Stéphane; Obeid, Ali

    2015-01-01

    Scheduling in semiconductor manufacturing is of vital importance due to the impact on production performance indicators such as equipment utilization, cycle time, and delivery times. With the increasing complexity of semiconductor manufacturing, ever-new products and demanding customers, scheduling plans for efficient production control become crucial. Scheduling and control are mutually dependent as control requires information from scheduling, for example, where jobs are processed, and sched...

  20. Special Issue on Manufacturing Plant Control Challenges and Issues: Guest editorial

    OpenAIRE

    Morel, Gérard; Pereira, Carlos Eduardo

    2007-01-01

    International audience This special issue of the IFAC journal on Control Engineering Practice contains improved selected papers of the 11th IFAC INCOM'04 Symposium on Information Control Problems in Manufacturing held in Brazil. The main purpose of INCOM'04 has been to point up international research and developments dealing with all the applications of automation, information and communication technologies in order to control and to manage the manufacturing plant within the e-enterprise. ...

  1. 78 FR 64018 - Manufacturer of Controlled Substances; Notice of Application; GE Healthcare

    Science.gov (United States)

    2013-10-25

    ... Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; GE Healthcare... September 12, 2013, GE Healthcare, 3350 North Ridge Avenue, Arlington Heights, Illinois 60004- 1412, made application by renewal to the Drug Enforcement Administration (DEA) to be registered as a bulk manufacturer...

  2. 78 FR 12103 - Manufacturer of Controlled Substances; Notice of Application; GE Healthcare

    Science.gov (United States)

    2013-02-21

    ... Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; GE Healthcare... August 31, 2012, GE Healthcare, 3350 North Ridge Avenue, Arlington Heights, Illinois 60004- 1412, made application by renewal to the Drug Enforcement Administration (DEA) to be registered as a bulk manufacturer...

  3. Plug-Based Microfluidics with Defined Surface Chemistry to Miniaturize and Control Aggregation of Amyloidogenic Peptides**

    OpenAIRE

    Meier, Matthias; Kennedy-Darling, Julia; Choi, Se Hoon; Norstrom, Eric M.; Sisodia, Sangram S; Ismagilov, Rustem F.

    2009-01-01

    Small with control: For miniaturization of protein aggregation experiments the interfacial chemistry must be controlled to avoid protein aggregation caused by interfacial adsorption. Plug-based microfluidics with defined surface chemistry (see schematic picture) can then be used to perform hundreds of aggregation experiments with volume-limited samples, such as cerebrospinal fluid from mice.

  4. Chemistry

    International Nuclear Information System (INIS)

    Research and development activities dealing with the chemical problems related to design and ultimate operation of molten-salt reactor systems are described. An experimental test stand was constructed to expose metallurgical test specimens to Te2 vapor at defined temperatures and deposition rates. To better define the chemistry of fluoroborate coolant, several aspects are being investigated. The behavior of hydroxy and oxy compounds in molten NaBF4 is being investigated to define reactions and compounds that may be involved in corrosion and/or could be involved in methods for trapping tritium. Two corrosion products of Hastelloy N, Na3CrF6 and Na5Cr3F14, were identified from fluoroborate systems. The evaluation of fluoroborate and alternate coolants continued. Research on the behavior of hydrogen and its isotopes is summarized. The solubilities of hydrogen, deuterium, and helium in Li2BeF4 are very low. The sorption of tritium on graphite was found to be significant (a few milligrams of tritium per kilogram of graphite), possibly providing a means of sequestering a portion of the tritium produced. Development of analytical methods continued with emphasis on voltammetric and spectrophotometric techniques for the in-line analysis of corrosion products such as Fe2+ and Cr3+ and the determination of the U3+/U4+ ratio in MSBR fuel salt. Similar studies were conducted with the NaBF4--NaF coolant salt. Information developed during the previous operation of the CSTF has been assessed and used to formulate plans for evaluation of in-line analytical methods in future CSTF operations. Electroanalytical and spectrophotometric research suggests that an electroactive protonic species is present in molten NaBF4--NaF, and that this species rapidly equilibrates with a volatile proton-containing species. Data obtained from the CSTF indicated that tritium was concentrated in the volatile species. (JGB)

  5. 78 FR 46613 - Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC

    Science.gov (United States)

    2013-08-01

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC... 10, 2013, Siegfried (USA), LLC., 33 Industrial Park Road, Pennsville, New Jersey 08070,...

  6. 78 FR 5500 - Manufacturer of Controlled Substances, Notice of Application; Siegfried (USA)

    Science.gov (United States)

    2013-01-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances, Notice of Application; Siegfried (USA... 19, 2012, Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey 08070, made application...

  7. 77 FR 70825 - Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC

    Science.gov (United States)

    2012-11-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Siegfried (USA), LLC... November 5, 2012, Siegfried (USA) LLC, 33 Industrial Park Road, Pennsville, New Jersey 08070,...

  8. 78 FR 23958 - Manufacturer of Controlled Substances; Notice of Application; Research Triangle Institute

    Science.gov (United States)

    2013-04-23

    ... following basic classes of controlled substances: Drug Schedule Marihuana (7360) I Cocaine (9041) II The Institute will manufacture marihuana, and cocaine derivatives for use by their customers in analytical...

  9. Surface chemistry: Key to control and advance myriad technologies

    OpenAIRE

    Yates, John T.; Campbell, Charles T.

    2011-01-01

    This special issue on surface chemistry is introduced with a brief history of the field, a summary of the importance of surface chemistry in technological applications, a brief overview of some of the most important recent developments in this field, and a look forward to some of its most exciting future directions. This collection of invited articles is intended to provide a snapshot of current developments in the field, exemplify the state of the art in fundamental research in surface chemi...

  10. Factors controlling global tropospheric ozone: roles of isoprene chemistry, tropospheric halogen chemistry, convection, and lightning NOx sources

    Science.gov (United States)

    Hu, L.; Jacob, D. J.; Zhang, Y.; Liu, X.; Zhang, L.

    2015-12-01

    Ozone is central to our understanding of tropospheric oxidant chemistry through its driving of radical cycles. Yet our understanding of factors determining its spatial distribution and long-term trend is still poor. In this work, we use the GEOS-Chem chemical transport model as a platform to test our current knowledge of key factors controlling tropospheric ozone. We evaluate the most recent GEOS-Chem simulation against in-situ data using ozonesonde networks from WOUDC and NOAA-GMD and using aircraft observations from MOZAIC/IAGOS, to examine the vertical distribution of modeled tropospheric ozone. Satellite observed ozone data from OMI (Ozone Monitoring Instrument) are used to assess the spatial distribution of the predicted ozone concentrations. We also examine different versions of GEOS-Chem outputs from historical benchmarks and from sensitivity runs (such as changing in chemistry and meteorological fields) for their capabilities to reproduce observed tropospheric ozone patterns. In this presentation, we interpret these analyses in terms of present understanding in isoprene chemistry, tropospheric bromine chemistry, lightning NOx sources and deep convection, and examine their implications for key model processes controlling the abundance and variability of global tropospheric ozone.

  11. Microeconomics of yield learning and process control in semiconductor manufacturing

    Science.gov (United States)

    Monahan, Kevin M.

    2003-06-01

    Simple microeconomic models that directly link yield learning to profitability in semiconductor manufacturing have been rare or non-existent. In this work, we review such a model and provide links to inspection capability and cost. Using a small number of input parameters, we explain current yield management practices in 200mm factories. The model is then used to extrapolate requirements for 300mm factories, including the impact of technology transitions to 130nm design rules and below. We show that the dramatic increase in value per wafer at the 300mm transition becomes a driver for increasing metrology and inspection capability and sampling. These analyses correlate well wtih actual factory data and often identify millions of dollars in potential cost savings. We demonstrate this using the example of grating-based overlay metrology for the 65nm node.

  12. Context-Based Orchestration for Control of Resource-Efficient Manufacturing Processes

    Directory of Open Access Journals (Sweden)

    Michael Schwarz

    2012-08-01

    Full Text Available The increasing competition between manufacturers, the shortening of innovation cycles and the growing importance of resource-efficient manufacturing demand a higher versatility of factory automation. Service-oriented approaches depict a promising possibility to realize new control architectures by encapsulating the functionality of mechatronic devices into services. An efficient discovery, context-based selection and dynamic orchestration of these services are the key features for the creation of highly adaptable manufacturing processes. We describe a semantic service discovery and ad-hoc orchestration system, which is able to react to new process variants and changed contextual information (e.g., failure of field devices, requirements on the consumption of resources. Because a standardized vocabulary, especially for the description of mechatronic functionalities, is still missing in the manufacturing domain, the semantic description of services, processes and manufacturing plants as well as the semantic interpretation of contextual information play an important part.

  13. 76 FR 5829 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2011-02-02

    ... controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I Amphetamine (1100) II... distribution to its customers. In reference to drug code 7360 (Marihuana), the company plans to...

  14. The contemporary controller's profile in a Chinese manufacturing context: The case of W company in China

    OpenAIRE

    Liu, Jing

    2013-01-01

    Abstract Study objectives The goal of this study is to research the controller's role in a Western manufacture company which operates in China. Prior researchers have focused their vision on the controller's change in Western countries, while the controller's role in China has been rarely known. And previous literature has already discussed some certain troubles faced by controllers. So in order to examine if the findings of the West also apply to Chinese controllers, two following re...

  15. Dimensional metrology for process and part quality control in micro manufacturing

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard; Tosello, Guido; Gasparin, Stefania; De Chiffre, Leonardo

    Micro manufacturing has gained interest over the last decade as the demand for micro mechanical components has increased. The need for dimensional metrology at micro scale is evident both in terms of quality assurance of components and products and in terms of process control. As critical...... dimensions are scaled down and geometrical complexity of objects is increased, the available measurement technologies appear not sufficient. New solutions for measuring principles and instrumentation, tolerancing rules and procedures as well as traceability and calibration are necessary if micro...... manufacturing is to develop into industrial manufacturing solutions. In this paper the application of dimensional precision metrology to both component and process quality control will be demonstrated. The parts investigated are micro injection moulded polymer parts, typical for the field of micro manufacturing....

  16. Surface control alloy substrates and methods of manufacture therefor

    Energy Technology Data Exchange (ETDEWEB)

    Fritzemeier, Leslie G. (Mendon, MA); Li, Qi (Marlborough, MA); Rupich, Martin W. (Framingham, MA); Thompson, Elliott D. (Coventry, RI); Siegal, Edward J. (Malden, MA); Thieme, Cornelis Leo Hans (Westborough, MA); Annavarapu, Suresh (Brookline, MA); Arendt, Paul N. (Los Alamos, NM); Foltyn, Stephen R. (Los Alamos, NM)

    2004-05-04

    Methods and articles for controlling the surface of an alloy substrate for deposition of an epitaxial layer. The invention includes the use of an intermediate layer to stabilize the substrate surface against oxidation for subsequent deposition of an epitaxial layer.

  17. 75 FR 53720 - Manufacturer of Controlled Substances; Notice of Application

    Science.gov (United States)

    2010-09-01

    ... classes of controlled substances listed in schedules I and II: Drug Schedule Marihuana (7360) I... distribution to its customers. In reference to drug code 7360 (Marihuana), the company plans to...

  18. Controlling organic chemical hazards in food manufacturing: a hazard analysis critical control points (HACCP) approach.

    Science.gov (United States)

    Ropkins, K; Beck, A J

    2002-08-01

    Hazard analysis by critical control points (HACCP) is a systematic approach to the identification, assessment and control of hazards. Effective HACCP requires the consideration of all hazards, i.e., chemical, microbiological and physical. However, to-date most 'in-place' HACCP procedures have tended to focus on the control of microbiological and physical food hazards. In general, the chemical component of HACCP procedures is either ignored or limited to applied chemicals, e.g., food additives and pesticides. In this paper we discuss the application of HACCP to a broader range of chemical hazards, using organic chemical contaminants as examples, and the problems that are likely to arise in the food manufacturing sector. Chemical HACCP procedures are likely to result in many of the advantages previously identified for microbiological HACCP procedures: more effective, efficient and economical than conventional end-point-testing methods. However, the high costs of analytical monitoring of chemical contaminants and a limited understanding of formulation and process optimisation as means of controlling chemical contamination of foods are likely to prevent chemical HACCP becoming as effective as microbiological HACCP. PMID:12224422

  19. Water chemistry control to meet the advanced design and operation of light water reactors

    International Nuclear Information System (INIS)

    Water chemistry control is one of the key technologies to establish safe and reliable operation of nuclear power plants. The road maps on R and D plans for water chemistry of nuclear power systems in Japan have been proposed along with promotion of R and D related water chemistry improvement for the advanced application of light water reactors (LWRs). The technical trends were divided into four categories, dose rate reduction, structural integrity, fuel integrity and radioactive waste reduction, and latest technical break through for each category was shown for the advanced application of LWRs. At the same time, the technical break through and the latest movements for regulation of water chemistry were introduced for each of major organizations related to nuclear engineering in the world. The conclusions were summarized as follows; 1. Water chemistry improvements might contribute to achieve the advanced application of LWRs, while water chemistry should be often changed to achieve the advanced application of LWRs. 2. Only one solution for water chemistry control was not obtained for achieving the advanced application of LWRs, but miscellaneous solutions were possible for achieving one. Optimal water chemistry control was desired for having the good practices for satisfying multi-targets at the same time and it was much affected by the plant unique systems and operational history. 3. That meant it was difficult to determine water chemistry regulation targets for achieving application of LWRs but it was necessary to prepare suitable guideline for good achievement of application of LWRs. That meant the guideline should be recommendation for good practice in the plant. 4. The water chemistry guide line should be modified along with progress of plant operation and water chemistry and related technologies. (author)

  20. Context-Based Orchestration for Control of Resource-Efficient Manufacturing Processes

    OpenAIRE

    Michael Schwarz; Ines Heck; Jochen Schlick; Matthias Loskyll

    2012-01-01

    The increasing competition between manufacturers, the shortening of innovation cycles and the growing importance of resource-efficient manufacturing demand a higher versatility of factory automation. Service-oriented approaches depict a promising possibility to realize new control architectures by encapsulating the functionality of mechatronic devices into services. An efficient discovery, context-based selection and dynamic orchestration of these services are the key features for the creatio...

  1. Hydrological Controls on Water Chemistry that Supports Freshwater Mussel Populations

    Science.gov (United States)

    Prestegaard, K. L.

    2012-12-01

    Native freshwater mussel species ranges and population sizes have been declining throughout N. America. Due to their sedentary nature, adult mussels are vulnerable to both local habitat changes (often associated with land-use changes, contaminants, and biological invaders) and to climate changes that can alter river flow regimes, bed stability, and water chemistry. The purpose of this study is to examine the relationship between water chemistry and hydrological events in rivers that support native mussel populations. USGS ion concentration and water quality (pH, temperature, conductivity) data were used to calculate saturation indices for aragonite. For some sites, electrical conductivity was highly correlated with calcium and bicarbonate concentrations and could be used to estimate concentrations when ion chemistry was not measured. Continuous water quality data from datasondes could thus be used to evaluate saturation indices for aragonite on a daily basis for 10-15 year periods. For the Delaware River, which has relatively few carbonate rocks in its watershed, tributary aragonite saturation tended to reflect local geological conditions. The lower main stem of the river integrates the water chemistry of the basin and also responds to climatic conditions. The lower Delaware supports aragonite precipitation approximately 50 days per year, with considerable inter-annual variability. During most years, aragonite precipitation could occur during both the spring and late summer periods, but years with heavy spring rains rather than snowmelt shifts aragonite precipitation to late summer periods. In 2011 when several major tropical storms hit the Delaware basin, streamflow was too dilute for aragonite precipitation for most of the summer period. These data suggest that hydrological changes associated with climatic changes may influence the water chemistry and affect the suitability of some rivers as mussel habitat.

  2. Microstructure-controllable Laser Additive Manufacturing Process for Metal Products

    Science.gov (United States)

    Huang, Wei-Chin; Chuang, Chuan-Sheng; Lin, Ching-Chih; Wu, Chih-Hsien; Lin, De-Yau; Liu, Sung-Ho; Tseng, Wen-Peng; Horng, Ji-Bin

    Controlling the cooling rate of alloy during solidification is the most commonly used method for varying the material microstructure. However, the cooling rate of selective laser melting (SLM) production is constrained by the optimal parameter settings for a dense product. This study proposes a method for forming metal products via the SLM process with electromagnetic vibrations. The electromagnetic vibrations change the solidification process for a given set of SLM parameters, allowing the microstructure to be varied via magnetic flux density. This proposed method can be used for creating microstructure-controllable bio-implant products with complex shapes.

  3. MANUFACTURING NON-CIRCULAR PARTS USING PROGRAMMABLE MULTIPLE-AXIS CONTROLLER

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Successful attempt is made to solve the problem of manufacturing non-circular parts with the aid of programmable multiple-axis controller(PMAC) integrated with high-speed electrical spindle. Principles of PMAC are introduced, and an NC-grinder system is integrated based on PMAC with proper software included. Control method and integration principle are discussed. Using PMAC's online measuring and time-based controlling, high-speed and high-precision manufacture of non-circular parts is accomplished, yielding satisfactory result, which sets an important foundation for development of high-speed and high-precision NC grinder aiming at machining of non-circular parts.

  4. Corporate Governance, Internal Control and over Investment under Insider Control: Evidence from Listed Manufacturing Companies in China

    OpenAIRE

    Yu Tuanye; Chen Chucan

    2013-01-01

    At present, there are more serious over investments in China's listed companies. Based on corporate governance and internal control, we build a driven framework of two paths of “direct driver” and “internal control driver”. With 3002 manufacture samples from 2008 to 2011, we investigate the relationships between internal control and overinvestment, management control and internal control, overinvestment and between various corporate governance factors and overinvestment. Empirical result show...

  5. 76 FR 30970 - Manufacturer of Controlled Substances; Notice of Registration

    Science.gov (United States)

    2011-05-27

    ... January 18, 2011, and published in the Federal Register on February 2, 2011, 76 FR 5829, AMRI Rensselaer... controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I Amphetamine (1100) II... distribution to its customers. In reference to drug code 7360 (Marihuana), the company plans to...

  6. North Carolina Tobacco Farmers' Changing Perceptions of Tobacco Control and Tobacco Manufacturers

    Science.gov (United States)

    Crankshaw, Erik C.; Beach, Robert H.; Austin, W. David; Altman, David G.; Jones, Alison Snow

    2009-01-01

    Purpose: To examine tobacco farmers' attitudes toward tobacco control, public health, and tobacco manufacturers in order to determine the extent to which rapidly changing economic conditions have influenced North Carolina tobacco farmer attitudes in ways that may provide tobacco control advocates with new opportunities to promote tobacco control…

  7. Solar Heating and Cooling for a Controls Manufacturing Plant Lumberton, New Jersey

    Science.gov (United States)

    1982-01-01

    Comprehensive report documents computer-controlled system which has separate solar-collector and cooling-tower areas located away from building and is completely computer controlled. System description, test data, major problems and resolution, performance, operation and maintenance, manufacturer's literature and drawing comprise part of 257-page report.

  8. System design and control integration for advanced manufacturing

    CERN Document Server

    Li, Han-Xiong

    2014-01-01

    Most existing robust design books address design for static systems, or achieve robust design from experimental data via the Taguchi method. Little work considers model information for robust design particularly for the dynamic system. This book covers robust design for both static and dynamic systems using the nominal model information or the hybrid model/data information, and also integrates design with control under a large operating region. This design can handle strong nonlinearity and more uncertainties from model and parameters.

  9. Optimisation and control of processes in apparel manufacturing

    OpenAIRE

    Carvalho, Helder

    2003-01-01

    The industrial production of garments and similar textile end products is an activity that has roots back to the 19th century, and that has profited immensely from continuous technological developments since its first emergence. However, several characteristics of the materials that are processed give rise to technical issues that are difficult to objectively manage and control. The limpness and elasticity of textiles make automated material handling and transportation within the shopfloor...

  10. Remote Robot Vision Control of a Flexible Manufacturing Cell

    OpenAIRE

    Anton, Silvia; Anton, Florin Daniel; Borangiu, Theodor

    2010-01-01

    The project was finished at the end of 2008 as part of the PRIC research program (Shared Research and Training Resources). The research project provide a communication and collaboration portal solution for linking the existing pilot platform with multiple V+ industrial robot-vision controllers from Adept Technology located in four University Labs from Romania (Bucharest, Craiova, Iasi and Galati). This allow teachers to train their student using robots and expensive devices which they do not ...

  11. 77 FR 9947 - Guidance for Industry: Early Clinical Trials With Live Biotherapeutic Products: Chemistry...

    Science.gov (United States)

    2012-02-21

    ... otherwise. In the Federal Register of October 14, 2010 (75 FR 63188), FDA announced the availability of the... Biotherapeutic Products: Chemistry, Manufacturing, and Control Information; Availability AGENCY: Food and Drug... Products: Chemistry, Manufacturing, and Control Information '' dated February 2012. The guidance...

  12. Scanner baseliner monitoring and control in high volume manufacturing

    Science.gov (United States)

    Samudrala, Pavan; Chung, Woong Jae; Aung, Nyan; Subramany, Lokesh; Gao, Haiyong; Gomez, Juan-Manuel

    2016-03-01

    We analyze performance of different customized models on baseliner overlay data and demonstrate the reduction in overlay residuals by ~10%. Smart Sampling sets were assessed and compared with the full wafer measurements. We found that performance of the grid can still be maintained by going to one-third of total sampling points, while reducing metrology time by 60%. We also demonstrate the feasibility of achieving time to time matching using scanner fleet manager and thus identify the tool drifts even when the tool monitoring controls are within spec limits. We also explore the scanner feedback constant variation with illumination sources.

  13. Performance Analysis of a Manufacturing Line Operated under Optimal Surplus-Based Production Control

    Directory of Open Access Journals (Sweden)

    K. K. Starkov

    2012-01-01

    Full Text Available We examine optimality and performance of a tandem manufacturing line driven by a surplus-based decentralized production control strategy. The main objective of this type of production strategies is to guarantee that the cumulative number of produced products follows the cumulative production demand on the output of the given network. The basic idea of surplus-based control strategy is presented for the case of one manufacturing machine. We prove that this strategy is optimal. Then, a flow model of a line composed of arbitrarily many machines with bounded buffers is analyzed. We prove that the surplus-based production control enables this network to efficiently follow the product demand and establish the relation between the efficiency in the production tracking error and the intermediate inventory levels of a line. Performance and robustness of the flow model of the closed-loop manufacturing line are illustrated by computer simulations.

  14. Part height control of laser metal additive manufacturing process

    Science.gov (United States)

    Pan, Yu-Herng

    Laser Metal Deposition (LMD) has been used to not only make but also repair damaged parts in a layer-by-layer fashion. Parts made in this manner may produce less waste than those made through conventional machining processes. However, a common issue of LMD involves controlling the deposition's layer thickness. Accuracy is important, and as it increases, both the time required to produce the part and the material wasted during the material removal process (e.g., milling, lathe) decrease. The deposition rate is affected by multiple parameters, such as the powder feed rate, laser input power, axis feed rate, material type, and part design, the values of each of which may change during the LMD process. Using a mathematical model to build a generic equation that predicts the deposition's layer thickness is difficult due to these complex parameters. In this thesis, we propose a simple method that utilizes a single device. This device uses a pyrometer to monitor the current build height, thereby allowing the layer thickness to be controlled during the LMD process. This method also helps the LMD system to build parts even with complex parameters and to increase material efficiency.

  15. 21 CFR 111.123 - What quality control operations are required for the master manufacturing record, the batch...

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What quality control operations are required for... for Quality Control § 111.123 What quality control operations are required for the master manufacturing record, the batch production record, and manufacturing operations? (a) Quality control...

  16. An Improved Multivariate T2 Control Chart for Individual Observations in Low Volume Manufacturing

    Institute of Scientific and Technical Information of China (English)

    Miao Rui(苗瑞); Wang Dongpeng; Yao Yingxue

    2004-01-01

    For multivariate statistical process quality control with individual observations, the usually recommended procedure is Hotelling's T2 control chart. Using the T2 statistic based on β distribution is an exact method for constructing multivariate control limits in low volume manufacturing, but it is not convenient in that the variation of sample size leads to a change in control limit. This paper presents an improved multivariate T2 control chart whose control limit does not change with sample size, which is especially useful when the sample size is small.

  17. Chemistry control at Genkai-4 during the construction and trial operation

    International Nuclear Information System (INIS)

    Chemistry control at PWR during its construction and trial operation has been improved at every cases. Without exception of No.4 unit in the Genkai Nuclear Power Plant, which went into commercial operation in July, 1977, some improved chemistry control methods were adopted. Here were described on the implemented chemistry controls at comparing with those of the preceding plants such as No.2 unit in the Sendai Plant and No.3 in the Genkai Plant. In order to minimize the radiation exposure during steady full operation, it is important to carry out appropriate primary chemistry control not only during full power operation but also during construction and trial operation. Some countermeasures were implemented to reduce buildup of corrosion products and facilitate their removal during shutdown. These methods could bring both effect of radiation source reduction and excellent secondary chemistry condition to the unit. In addition, these results during its construction and trial operation could be expected to lead optimum water chemistry condition at the steady full power operation. (G.K.)

  18. 77 FR 60145 - Manufacturer of Controlled Substances; Notice of Registration; Apertus Pharmaceuticals, LLC

    Science.gov (United States)

    2012-10-02

    ... Pharmaceuticals, LLC By Notice dated June 4, 2012, and published in the Federal Register on June 12, 2012, 77 FR 35058, Apertus Pharmaceuticals, LLC., 331 Consort Drive, St Louis, Missouri 63011, made application to... registration of Apertus Pharmaceuticals, LLC., to manufacture the listed basic classes of controlled...

  19. 77 FR 30028 - Manufacturer of Controlled Substances; Notice of Registration; Cedarburg Pharmaceuticals, Inc.

    Science.gov (United States)

    2012-05-21

    ... Pharmaceuticals, Inc. By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2324, Cedarburg Pharmaceuticals, Inc., 870 Badger Circle, Grafton, Wisconsin 53024, made... Cedarburg Pharmaceuticals, Inc. to manufacture the listed basic classes of controlled substances...

  20. 78 FR 12104 - Manufacturer of Controlled Substances; Notice of Registration; Cedarburg Pharmaceuticals, Inc.

    Science.gov (United States)

    2013-02-21

    ... Pharmaceuticals, Inc. By Notice dated November 5, 2012, and published in the Federal Register on November 13, 2012, 77 FR 67676, Cedarburg Pharmaceuticals, Inc., 870 Badger Circle, Grafton, Wisconsin 53024, made... of Cedarburg Pharmaceuticals, Inc., to manufacture the listed basic classes of controlled...

  1. 78 FR 69134 - Manufacturer of Controlled Substances; Notice of Registration; Apertus Pharmaceuticals

    Science.gov (United States)

    2013-11-18

    ... Pharmaceuticals By Notice dated July 23, 2013, and published in the Federal Register on July 31, 2013, 78 FR 46372, Apertus Pharmaceuticals, 331 Consort Drive, St Louis, Missouri 63011, made application by renewal to the... of Apertus Pharmaceuticals to manufacture the listed basic classes of controlled substances...

  2. Changes in production control required for untended operation of a flexible manufacturing cell

    NARCIS (Netherlands)

    Slomp, Jannes; Stecke, Kathryn E.

    2012-01-01

    This article examines and improves the production control system of a firm that wants to operate its flexible manufacturing cell (FMC) in an untended third shift. The FMC consists of a machining centre, a pallet storage, a rail-guided transport vehicle for pallets and a clamping/unclamping station.

  3. 77 FR 72409 - Manufacturer of Controlled Substances; Notice of Application: Siemens Healthcare Diagnostics, Inc.

    Science.gov (United States)

    2012-12-05

    ... Enforcement Administration Manufacturer of Controlled Substances; Notice of Application: Siemens Healthcare... notice that on November 7, 2012, Siemens Healthcare Diagnostics, Inc., Attn: RA, 100 GBC Drive, Mail Stop 514, Newark, Delaware 19702, made application by renewal to the Drug Enforcement Administration...

  4. 77 FR 31390 - Manufacturer of Controlled Substances; Notice of Registration; Sigma Aldrich Research...

    Science.gov (United States)

    2012-05-25

    ... February 6, 2012, 77 FR 5847, Sigma Aldrich Research Biochemicals, Inc., 1-3 Strathmore Road, Natick... Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Sigma Aldrich....C. 823(a) and determined that the registration of Sigma Aldrich Research Biochemicals, Inc....

  5. 78 FR 12102 - Manufacturer of Controlled Substances; Notice of Application; Sigma Aldrich Research Biochemicals...

    Science.gov (United States)

    2013-02-21

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Sigma Aldrich...), this is notice that on November 21, 2012, Sigma Aldrich Research Biochemicals, Inc., 1-3...

  6. 77 FR 60145 - Manufacturer of Controlled Substances; Notice of Application; Sigma Aldrich Research Biochemicals...

    Science.gov (United States)

    2012-10-02

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application; Sigma Aldrich... is notice that on August 2, 2012, Sigma Aldrich Research Biochemicals, Inc., 1-3 Strathmore...

  7. 78 FR 64020 - Manufacturer of Controlled Substances; Notice of Registration; Sigma Aldrich Research...

    Science.gov (United States)

    2013-10-25

    ..., 2013, 78 FR 33442, Sigma Aldrich Research Biochemicals, Inc., 1-3 Strathmore Road, Natick... Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Sigma Aldrich... in 21 U.S.C. 823(a), and determined that the registration of Sigma Aldrich Research Biochemicals,...

  8. 78 FR 32458 - Manufacturer of Controlled Substances; Notice of Registration; Sigma Aldrich Research...

    Science.gov (United States)

    2013-05-30

    ... February 21, 2013, 78 FR 12102, Sigma ] Aldrich Research Biochemicals, Inc., 1-3 Strathmore Road, Natick... Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Sigma Aldrich.... DEA has considered the factors in 21 U.S.C. 823(a) and determined that the registration of...

  9. 78 FR 33442 - Manufacturer of Controlled Substances; Notice of Application Sigma Aldrich Research Biochemicals...

    Science.gov (United States)

    2013-06-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE Drug Enforcement Administration Manufacturer of Controlled Substances; Notice of Application Sigma Aldrich Research... that on May 7, 2013, Sigma Aldrich Research Biochemicals, Inc., 1-3 Strathmore Road,...

  10. 78 FR 33442 - Manufacturer of Controlled Substances; Notice of Registration; GE Healthcare

    Science.gov (United States)

    2013-06-04

    ... Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; GE Healthcare By Notice dated February 8, 2013 and published in the Federal Register on February 21, 2013, 78 FR 12103, GE Healthcare, 3350 North Ridge Avenue, Arlington Heights, Illinois 60004-1412, made application by renewal...

  11. 77 FR 30027 - Manufacturer of Controlled Substances; Notice of Registration; Siegfried (USA)

    Science.gov (United States)

    2012-05-21

    ... Enforcement Administration Manufacturer of Controlled Substances; Notice of Registration; Siegfried (USA) By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2323, Siegfried (USA), 33 Industrial Park Road, Pennsville, New Jersey 08070, made application by renewal to...

  12. 77 FR 47108 - Manufacturer of Controlled Substances; Notice of Application; Cerilliant Corporation

    Science.gov (United States)

    2012-08-07

    ... narcotic raw material are not appropriate. 72 FR 3417(2007). Any bulk manufacturer who is presently, or is..., 1975, 40 FR 43745-46, all applicants for registration to import a basic class of any controlled...-Dimethoxy-4-(n)-propylthiophenethylamine I (7348). Marihuana (7360) I Tetrahydrocannabinols (7370)...

  13. 78 FR 46372 - Manufacturer of Controlled Substances; Notice of Registration; Research Triangle Institute

    Science.gov (United States)

    2013-07-31

    ... Institute By Notice dated April 16, 2013, and published in the Federal Register on April 23, 2013, 78 FR... classes of controlled substances: Drug Schedule Marihuana (7360) I Cocaine (9041) II The Institute will manufacture marihuana, and cocaine derivatives for use by their customers in analytical kits, reagents,...

  14. 77 FR 75670 - Manufacturer of Controlled Substances, Notice of Registration, AMRI Rensselaer, Inc.

    Science.gov (United States)

    2012-12-21

    .... By Notice dated July 30, 2012, and published in the Federal Register on August 7, 2012, 77 FR 47114... basic classes of controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I... reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol as a...

  15. 77 FR 52368 - Manufacturer of Controlled Substances; Notice of Registration; Austin Pharma, LLC.

    Science.gov (United States)

    2012-08-29

    .... By Notice dated May 9, 2012, and published in the Federal Register on May 21, 2012, 77 FR 30027... basic classes of controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I... customers. In reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol...

  16. Adaptive Process Controls and Ultrasonics for High Temperature PEM MEA Manufacture

    Energy Technology Data Exchange (ETDEWEB)

    Walczyk, Daniel F. [Rensselaer Polytechnic Inst., Troy, NY (United States)

    2015-08-26

    The purpose of this 5-year DOE-sponsored project was to address major process bottlenecks associated with fuel cell manufacturing. New technologies were developed to significantly reduce pressing cycle time for high temperature PEM membrane electrode assembly (MEA) through the use of novel, robust ultrasonic (U/S) bonding processes along with low temperature (<100°C) PEM MEAs. In addition, greater manufacturing uniformity and performance was achieved through (a) an investigation into the causes of excessive variation in ultrasonically and thermally bonded MEAs using more diagnostics applied during the entire fabrication and cell build process, and (b) development of rapid, yet simple quality control measurement techniques for use by industry.

  17. The separation of ownership and control and investment decisions in Mexican manufacturing firms

    OpenAIRE

    Ruiz-Porras, Antonio; Lopez-Mateo, Celina

    2010-01-01

    We study how the ownership and control structures may explain investment decisions of Mexican manufacturing firms. We study them with aggregate indexes and the assessment of several regression sets. We use measures of ownership, management and agency costs. The econometric analysis uses longitudinal census data for 182 industries. Our findings support the claim that agency costs, as a measure of the separation of management and control, and firms` size can explain investment decisions. Furthe...

  18. "The Impact Of Budgeting And Budgetary Control On The Performance Of Manufacturing Company In Nigeria "

    OpenAIRE

    Siyanbola, Trimisiu Tunji

    2013-01-01

    This study, the impact of budgeting and budgetary control on the performance of manufacturing company in Nigeria, was conducted using Cadbury Nigeria Plc, as case study. Since wants are plenty while resources are limited, every organisation tends to find means by which it can get what it wants with the limited resources at its disposal. Therefore, firms seek to adopt the concept of budgeting and budgetary control to satisfy their needs at the least possible cost and at the same time fulfill...

  19. Quality control of laser- and powder bed-based Additive Manufacturing (AM) technologies

    Science.gov (United States)

    Berumen, Sebastian; Bechmann, Florian; Lindner, Stefan; Kruth, Jean-Pierre; Craeghs, Tom

    The quality of metal components manufactured by laser- and powder bed-based additive manufacturing technologies has continuously been improved over the last years. However, to establish this production technology in industries with very high quality standards the accessibility of prevalent quality management methods to all steps of the process chain needs still to be enhanced. This publication describes which tools are and will be available to fulfil those requirements from the perspective of a laser machine manufacturer. Generally five aspects of the part building process are covered by separate Quality Management (QM) modules: the powder quality, the temperature management, the process gas atmosphere, the melt pool behaviour and the documentation module. This paper sets the focus on melt pool analysis and control.

  20. Integration of process-oriented control with systematic inspection in FRAMATOME-FBFC fuel manufacturing

    International Nuclear Information System (INIS)

    The classical approach to quality control is essentially based on final inspection of the product conducted through a qualified process. The main drawback of this approach lies in the separation and , therefore, in the low feedback between manufacturing and quality control, leading to a very static quality system. As a remedy, the modern approach to quality management focuses on the need for continuous improvement through process-oriented quality control. In the classical approach, high reliability of nuclear fuel and high quality level of the main characteristics are assumed to be attained, at the manufacturing step, through 100% inspection of the product, generally with automated inspection equipment. Such a 100% final inspection is not appropriate to obtain a homogeneous product with minimum variability, and cannot be a substitute for the SPC tools (Statistical Process Control) which are rightly designed with this aim. On the other hand, SPC methods, which detect process changes and are used to keep the process under control, leading to the optimal distribution of the quality characteristics, do not protect against non systematic or local disturbances, at low frequency. Only systematic control is capable of detecting local quality troubles. In fact, both approaches, SPC and systematic inspection, are complementary , because they are remedies for distinct causes of process and product changes. The term 'statistical' in the expression 'SPC' refers less to the sampling techniques than to the control of global distribution parameters of product or process variables (generally location and dispersion parameters). The successive integration levels of process control methods with systematic inspection are described and illustrated by examples from FRAMATOME-FBFC fuel manufacturing, from the simple control chart for checking the performance stability of automated inspection equipment to the global process control system including systematic inspection. This kind of

  1. Operating experience in correcting severe secondary chemistry upsets by controlling makeup water organics (TOC)

    International Nuclear Information System (INIS)

    In this paper following observations are presented: conductivity and chloride excursions in steam condensate were directly linked to makeup water quality. Data strongly suggests that the breakdown of makeup water organics was responsible for substandard condensate water quality; although the short-term effects of gross organic contamination have been documented, the longer term consequences of continuous exposure by moderate organic levels needs to be addressed; a greater understanding of the organic removal efficiency of the various water purification technologies is essential to controlling TOC contamination; and a much better understanding of makeup plant chemistry and the interrelationship of makeup water contamination and plant chemistry has proven essential to optimizing plant performance and guaranteeing the best possible steam chemistry. The role of the chemistry group as an active participant in operations has been proven at Kewaunee Nuclear Plant

  2. Design and Implementation of Distributed Numerical Control in Flexible Manufacturing System

    Institute of Scientific and Technical Information of China (English)

    周炳海; 余传猛; 奚立峰; 曹永上

    2004-01-01

    To monitor, control and manage the work process ofcomputer numerical control machine tools in a flexible manufacturing system (FMS) effectively, the distributed numerical control (distributed-NC) software should be innovated with the characteristics of modularization and reconfiguration. In this paper, firstly, distributed-NC functions in the FMS environment are described. Then, we present a design and development method of the real time distributed-NC that is on the basis of the re-configurable software and hardware platform and with an object-oriented model concept. Finally, to verify the proposed method, the distributed-NC software has been implemented in VC + +6.0 and has been tested in connection with the different physical flexible manufacturing shops.

  3. Manufacture and quality control of concrete for Ikata Nuclear Power Station, Shikoku Electric Power Co., Inc

    International Nuclear Information System (INIS)

    Ikata Nuclear Power Station, only one nuclear power station in Shikoku, is located at the root of Sada Peninsula on Seto Inland sea side. At present, No.1 and No.2 plants of 566 MW each are in commercial operation, and on the east side, No.3 plant is under construction. No.3 plant is a PWR type plant of 890 MWe output, and the start of commercial operation is scheduled in March, 1995. In the construction of No.3 plant, the concrete used for civil engineering and building works is about 430,000 m3, and for the improvement of the quality control of concrete, the pursuit of economic efficiency, the fostering of concrete technology of employee and the coprosperity with local industries, the facilities for manufacturing concrete were constructed within the premise of the power station. The amount of use of concrete and respective materials classified by respective fiscal years, and the amount of manufacture of concrete that determines the scale of the concrete plant are shown. As to the construction of the concrete plant, the foundation work was started in March, 1987, and the machine foundation and building works were started in May, 1987. The acceptance was completed on August 17, 1987. The facilities of manufacturing concrete, the manufacture of concrete, and the quality control of materials and concrete are reported. (author)

  4. 78 FR 64425 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-10-29

    ... Manufacturing Practice and Hazard Analysis and Risk- Based Preventive Controls for Food for Animals; Public... risk-based preventive controls for animal food. This proposed rule is one of several proposed rules... manufacturing, processing, packing, and holding of animal food. Second, it would include new preventive...

  5. A prototype expert system 'SMART' for water chemistry control in reactor water circuits

    International Nuclear Information System (INIS)

    The operational safety of a power plant depends mainly on the material compatibility of the system materials with the environment. However, for an operating plant, the material is almost fixed and hence one can improve the safety by controlling the surrounding environment. From the economy point of view, the plant availability factor as well as plant life extension (PLEX) are important considerations and these necessitate a systematic approach for continuous parametric monitoring, rapid data analysis and diagnosis for controlling the water chemistry regime. A prototype expert system 'SMART' was developed in BASIC language. The expert system consists of four modules. The DATA HANDLER module controls all the data handling functions and graphical display of the data parameters. It also generates weekly and monthly reports of the water chemistry data. The DATA INTERPRETER module compares the experimental data with the theoretically calculated values and predicts the presence of impurity ingress in the system. The CHEMISTRY EXPERT contains the knowledge base about the various sub-systems. All the water chemistry specifications are translated in the form of IF... THEN.. rules and are stored in this module. The expert system inferences with the forward chain reasoning mechanism to identify the diagnostic parameters by consulting the knowledge base and applying the appropriate rules. The ACTION EXPERT module collects all the diagnostic parameters and suggests the operator, the remedial actions/counter measures that should be taken immediately. This rule based system can be expanded to accommodate different water chemistry regimes. (author)

  6. Chemistry with spatial control using particles and streams†

    OpenAIRE

    Kalinin, Yevgeniy V.; Murali, Adithya; Gracias, David H.

    2012-01-01

    Spatial control of chemical reactions, with micro- and nanometer scale resolution, has important consequences for one pot synthesis, engineering complex reactions, developmental biology, cellular biochemistry and emergent behavior. We review synthetic methods to engineer this spatial control using chemical diffusion from spherical particles, shells and polyhedra. We discuss systems that enable both isotropic and anisotropic chemical release from isolated and arrayed particles to create inhomo...

  7. Control of radical chemistry in the AdoMet-radical enzymes

    OpenAIRE

    Duschene, Kaitlin S.; Veneziano, Susan E.; Silver, Sunshine C.; Broderick, Joan B.

    2009-01-01

    The radical AdoMet superfamily comprises a diverse set of >2800 enzymes that utilize iron-sulfur clusters and S-adenosylmethionine (SAM or AdoMet) to initiate a diverse set of radical-mediated reactions. The intricate control these enzymes exercise over the radical transformations they catalyze is an amazing feat of elegance and sophistication in biochemistry. This review focuses on the accumulating evidence for how these enzymes control this remarkable chemistry, including controlling the re...

  8. Control of criticality risk in the manufacture of fuel elements for research reactors

    International Nuclear Information System (INIS)

    The control of criticality risk in a chemical plant adopts different forms according to the quantities of fissile material and the type of compounds used. This work presents the treatment of the critical excursion risk adopted in production plants of U3 O8 and manufacturing plants of fuel elements for research reactors, located in Constituyentes Atomic Center. The possible events and accidents related to the fissile material control are analyzed, and the systems of administrative control and intrinsic safety through engineering are described. (Author)

  9. Interaction of Units and Research Methods of Control Performances of Distributed Manufacturing Information System

    Institute of Scientific and Technical Information of China (English)

    ZHANG Kai-sheng; SUN Yan-ming; ZHENG Shi-xiong

    2008-01-01

    In order to analyze the function demand of the distributed manufacturing information system as well as its control demand,and eliminate information ambiguity among system units to integrate sernantics,the abstract Agent model and computational structure of each unit was presented based on flexible coupling automata.The autonomy of each unit was investigated in this foundation.The system unit was described usmg the Web Ontology Language (OWL) ontology.And the system semantics was also integrated.On these basics the communication among the system units was analyzed with an example of interaction between a machine and a warehouse.The control performances of information system units were investigated usmg Boolean matrix as a substitute for traditional process in RWtheory,which reduced the computational complexity.This work established the foundation for the demand analysis,design and development of the distributed manufacture information system.

  10. Process and quality control in manufacturing of nuclear fuel assemblies of LWRs

    International Nuclear Information System (INIS)

    Manufacturing of nuclear fuel assemblies requires a multitude of different process and quality methods to assure and maintain a high quality level. In recent years methods have been applied which prevent deviations rather than detect deviant products. This paper gives an example on how to control a complex manufacturing process by using a small number of key parameters and second, it demonstrates the importance of graphical data evaluation and presentation methods. In the past many product and product characteristics were inspected m comparison with specification limits only. However, todays methods allow the early identification of trends, increase of variation, shifts disturbances etc. before the product characteristics exceed the specification limits. These methods are process control charts, x-y-plots, boxplots, failure mode and effect analysis (FMEA), process capability numbers and others. This paper demonstrates the beneficial use of some of the methods by presenting selected examples applied at Advanced Nuclear Fuels GmbH (ANF). (author)

  11. Statistical tools and control of internal lubricant content of inhalation grade HPMC capsules during manufacture.

    Science.gov (United States)

    Ayala, Guillermo; Díez, Fernando; Gassó, María T; Jones, Brian E; Martín-Portugués, Rafael; Ramiro-Aparicio, Juan

    2016-04-30

    The internal lubricant content (ILC) of inhalation grade HPMC capsules is a key factor to ensure good powder release when the patient inhales a medicine from a dry powder inhaler (DPI). Powder release from capsules has been shown to be influenced by the ILC. The characteristics used to measure this are the emitted dose, fine particle fraction and mass median aerodynamic diameter. In addition the ILC level is critical for capsule shell manufacture because it is an essential part of the process that cannot work without it. An experiment has been applied to the manufacture of inhalation capsules with the required ILC. A full factorial model was used to identify the controlling factors and from this a linear model has been proposed to improve control of the process. PMID:26899981

  12. Hierarchical tailoring of strut architecture to control permeability of additive manufactured titanium implants.

    Science.gov (United States)

    Zhang, Z; Jones, D; Yue, S; Lee, P D; Jones, J R; Sutcliffe, C J; Jones, E

    2013-10-01

    Porous titanium implants are a common choice for bone augmentation. Implants for spinal fusion and repair of non-union fractures must encourage blood flow after implantation so that there is sufficient cell migration, nutrient and growth factor transport to stimulate bone ingrowth. Additive manufacturing techniques allow a large number of pore network designs. This study investigates how the design factors offered by selective laser melting technique can be used to alter the implant architecture on multiple length scales to control and even tailor the flow. Permeability is a convenient parameter that characterises flow, correlating to structure openness (interconnectivity and pore window size), tortuosity and hence flow shear rates. Using experimentally validated computational simulations, we demonstrate how additive manufacturing can be used to tailor implant properties by controlling surface roughness at a microstructual level (microns), and by altering the strut ordering and density at a mesoscopic level (millimetre). PMID:23910314

  13. Performance analysis for tandem manufacturing lines under variable structure production control method

    OpenAIRE

    Starkov, Konstantin; Pogromsky, Alexander; Rooda, J.E.

    2012-01-01

    Abstract In this paper authors introduce novel results on performance for surplus-based decentralized production control method. The main objective of this production method is to guarantee that the cumulative number of produced products follows the cumulative production demand on the output of any given network. As a starting point of our research a general idea of this method is presented for the case of one manufacturing machine. Then our analysis is extended to a line of $N$ ma...

  14. Applying TOC in the production planning and control of a knitwear manufacturer

    OpenAIRE

    Yang, Anni

    2015-01-01

    Purpose – This study seeks to discuss the theory of constraint (TOC)’s application and implications in a knitwear manufacturer, especially on production planning and control, to improve its operational performance and consequently achieve the goal of making money. Design/methodology/approach – This report presents a case study of a specific company in the textile and clothing industry. In-depth interviews have been used to describe the current business scenario of the company and help to ...

  15. Nonlinear model-based control of thin-film drying for continuous pharmaceutical manufacturing

    OpenAIRE

    Mesbah, A.; Ford Versypt, AN; Zhu, X.; Braatz, RD

    2014-01-01

    This paper considers the model-based control of composition and thickness for a thin-film drying process used in the continuous manufacturing of pharmaceutical tablets. In this nonlinear distributed dynamical system, a drug formulation solution is coated onto a moving surface and then dried to form thin films of approximately 250 μm in thickness. A dynamic optimizer is designed that employs a first-principles process model to simulate the spatial distribution of solvent concentration in the f...

  16. PWR water chemistry controls: a perspective on industry initiatives and trends relative to operating experience and the EPRI PWR water chemistry guidelines

    International Nuclear Information System (INIS)

    An effective PWR water chemistry control program must address the following goals: Minimize materials degradation (e.g., PWSCC, corrosion of fuel, corrosion damage of steam generator (SG) tubes); Maintain fuel integrity and good performance; Minimize corrosion product transport (e.g., transport and deposition on the fuel, transport into the SGs where it can foul tube surfaces and create crevice environments for the concentration of corrosive impurities); Minimize dose rates. Water chemistry control must be optimized to provide overall improvement considering the sometimes variant constraints of the goals listed above. New technologies are developed for continued mitigation of materials degradation, continued fuel integrity and good performance, continued reduction of corrosion product transport, and continued minimization of plant dose rates. The EPRI chemistry program, in coordination with other EPRI programs, strives to improve these areas through application of chemistry initiatives, focusing on these goals. This paper highlights the major initiatives and issues with respect to PWR primary and secondary system chemistry and outlines the recent, on-going, and proposed work to effectively address them. These initiatives are presented in light of recent operating experience, as derived from EPRI's PWR chemistry monitoring and assessment program, and EPRI's water chemistry guidelines. (author)

  17. Studies in process modeling, design, monitoring, and control, with applications to polymer composites manufacturing

    Science.gov (United States)

    Srinivasagupta, Deepak

    2002-01-01

    High material and manufacturing costs have hindered the introduction of advanced polymer composite materials into mainstream civilian applications such as automotive. Even though high-fidelity models for several polymer composite manufacturing processes have become available over the past several years and offer significant benefits in manufacturing cost reduction, concerns about their inflexibility and maintenance has adversely affected their widespread usage. This research seeks to advance process modeling and design in polymer composites manufacturing to address these concerns. Other more general issues in measurement validation and distributed control are also addressed. Using a rigorous 3-D model of the injected pultrusion (IP) process validated recently, an algorithm was developed for process and equipment design with integrated economic, operability and environmental considerations. The optimum design promised enhanced throughput as well as reduction in the time and expenses of the current purely experimental approaches. Scale-up issues in IP were analyzed, and refinements to overcome some drawbacks in the model were suggested. The process model was then extended to simulate the co-injection resin transfer molding (CIRTM) process used for manufacture of foam-core sandwich composites. A 1-D isothermal model for real-time control was also developed. Process optimization using these models and experimental parametric studies increased the debond fracture toughness of sandwiches by 78% over current technology. To ensure the availability of validated measurements from process instrumentation, a novel in-situ sensor modeling approach to sensor validation was proposed. Both active and passive, time and frequency domain techniques were developed, and experimentally verified using temperature and flow sensors. A model-based dynamic estimator to predict the true measurement online was also validated. The effect of network communication delay on stability and control

  18. Advanced analytical techniques for boiling water reactor chemistry control

    International Nuclear Information System (INIS)

    The analytical techniques applied can be divided into 5 classes: OFF-LINE (discontinuous, central lab), AT-LINE (discontinuous, analysis near loop), ON-LINE (continuous, analysis in bypass). In all cases pressure and temperature of the water sample are reduced. In a strict sense only IN-LINE (continuous, flow disturbance) and NON-INVASIVE (continuous, no flow disturbance) techniques are suitable for direct process control; - the ultimate goal. An overview of the analytical techniques tested in the pilot loop is given. Apart from process and overall water quality control, standard for BWR operation, the main emphasis is on water impurity characterization (crud particles, hot filtration, organic carbon); on stress corrosion crackling control for materials (corrosion potential, oxygen concentration) and on the characterization of the oxide layer on austenites (impedance spectroscopy, IR-reflection). The above mentioned examples of advanced analytical techniques have the potential of in-line or non-invasive application. They are different stages of development and are described in more detail. 28 refs, 1 fig., 5 tabs

  19. Computational manufacturing

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    This paper presents a general framework for computational manufacturing. The methodology of computational manufacturing aims at integrating computational geometry, machining principle, sensor information fusion, optimization, computational intelligence and virtual prototyping to solve problems of the modeling, reasoning, control, planning and scheduling of manufacturing processes and systems. There are three typical problems in computational manufacturing, i.e., scheduling (time-domain), geometric reasoning (space-domain) and decision- making (interaction between time-domain and space-domain). Some theoretical fundamentals of computational manufacturing are also discussed.

  20. Combination of click chemistry and controlled radical polymerization for synthesis of advanced polymer drug delivery systems

    Czech Academy of Sciences Publication Activity Database

    Pechar, Michal; Pola, Robert; Braunová, Alena; Laga, Richard; Ulbrich, Karel

    2013-01-01

    Roč. 9, č. 1 (2013), s. 106-107 /3P10/. ISSN 1336-7242. [Zjazd chemikov /65./. 09.09.2013-13.09.2013, Tatranské Matliare] R&D Projects: GA ČR GCP207/12/J030 Institutional support: RVO:61389013 Keywords : polymer conjugates * controlled drug delivery * diagnostics of tumors Subject RIV: CD - Macromolecular Chemistry

  1. Kinetic controlled affinity labeling of target enzyme with thioester chemistry.

    Science.gov (United States)

    Tomohiro, Takenori; Nakabayashi, Masahiro; Sugita, Yuka; Morimoto, Shota

    2016-08-01

    High specificity has been an important feature in affinity labeling for target profiling. Especially, to label targets via rapidly progressing reactions with consumption of ligand (probe), high specificity of reaction with common functional groups of target protein should be achieved without reactions with similar groups of non-target proteins. Herein, we demonstrate the kinetic controlled affinity labeling of acyl CoA synthetase using a fatty acid analogue containing a phenylthioester linkage. High specificity was attained by accelerating the labeling rate in the binding pocket. This approach could be useful for profiling a series of target enzymes and transporters in signal transduction pathways. PMID:27298000

  2. Biological forcing controls the chemistry of the coral exoskeleton

    Science.gov (United States)

    Meibom, A.; Mostefaoui, S.; Cuif, J.; Yurimoto, H.; Dauphin, Y.; Houlbreque, F.; Dunbar, R.; Constantz, B.

    2006-12-01

    A multitude of marine organisms produce calcium carbonate skeletons that are used extensively to reconstruct water temperature variability of the tropical and subtropical oceans - a key parameter in global climate-change models. Such paleo-climate reconstructions are based on the notion that skeletal oxygen isotopic composition and certain trace-element abundances (e.g., Sr/Ca and Mg/Ca ratios) vary in response to changes in the water temperature. However, it is a fundamental problem that poorly understood biological processes introduce large compositional deviations from thermodynamic equilibrium and hinder precise calibrations of many paleo-climate proxies. Indeed, the role of water temperature in controlling the composition of the skeleton is far from understood. We have studied trace-element abundances as well as oxygen and carbon isotopic compositions of individual skeletal components in the zooxanthellate and non-zooxanthellate corals at ultra-structural, i.e. micrometer to sub-micrometer length scales. From this body of work we draw the following, generalized conclusions: 1) Centers of calcification (COC) are not in equilibrium with seawater. Notably, the Sr/Ca ratio is higher than expected for aragonite equilibrium with seawater at the temperature at which the skeleton was formed. Furthermore, the COC are further away from equilibrium with seawater than fibrous skeleton in terms of stable isotope composition. 2) COC are dramatically different from the fibrous aragonite skeleton in terms of trace element composition. 3) Neither trace element nor stable isotope variations in the fibrous (bulk) part of the skeleton are directly related to changes in SST. In fact, changes in SST can have very little to do with the observed compositional variations. 4) Trace element variations in the fibrous (bulk) part of the skeleton are not related to the activity of zooxanthellae. These observations are directly relevant to the issue of biological versus non

  3. Start-up conditions and the performance of women - and men - controlled businesses in manufacturing industries

    Directory of Open Access Journals (Sweden)

    Otilia Driga

    2010-01-01

    Full Text Available Recent research into the economic performance of women-controlled firms suggests that their underperformance may not be the result of differences in the managerial ability of women as compared to men, and that it may in fact be a consequence of differing levels of start-up resources. Using accounting data, we examine the effects that selected start-up conditions have had on the observed economic performance of a sample of 4450 Spanish manufacturing firms. The results, which indicate significant differences in the initial conditions and show lower levels of assets and employee numbers in women-controlled firms, have implications for the economic performance of such firms.

  4. The need for artificial intelligence as an aid in controlling a manufacturing operation

    Science.gov (United States)

    Weyand, J.

    AI applications to industrial production and planning are discussed and illustrated with diagrams and drawings. Applications examined include flexible automation of manufacturing processes (robots with open manual control, robots programmable to meet product specifications, self-regulated robots, and robots capable of learning), flexible fault detection and diagnostics, production control, and overall planning and management (product strategies, marketing, determination of development capacity, site selection, project organization, and technology investment strategies). For the case of robots, problems in the design and operation of a state-of-the-art machine-tool cell (for hole boring, milling, and joining) are analyzed in detail.

  5. Water Chemistry Control in Reducing Corrosion and Radiation Exposure at PWR Reactor

    International Nuclear Information System (INIS)

    Water chemistry control plays an important role in relation to plant availability, reliability and occupational radiation exposures. Radiation exposures of nuclear plant workers are determined by the radiation rate dose and by the amount maintenance and repair work time Water chemistry has always been, from beginning of operation of power Pressurized Water Reactor, an important factor in determining the integrity of reactor components, fuel cladding integrity and minimize out of core radiation exposures. For primary system, the parameters to control the quality of water chemistry have been subject to change in time. Reactor water coolant pH need to be optimally controlled and be operated in range pH 6.9 to 7.4. At pH lower than 6.9, cause increasing the radiation exposure level and increasing coolant water pH higher than 7.4 will decrease radiation exposure level but increasing risk to fuel cladding and steam generator tube. Since beginning 90 decade, PWR water coolant pH tend to be operated at pH 7.4. This paper will discuss concerning water chemistry development in reducing corrosion and radiation exposure dose in PWR reactor. (author)

  6. Surface chemistry interventions to control boiler tube fouling

    International Nuclear Information System (INIS)

    The adsorption of ammonia, morpholine, ethanolamine, and dimethylamine onto the surfaces of colloidal magnetite and hematite was measured at 25oC. The effect of the adsorption on the surface potential was quantified by measuring the resulting shift in the isoelectric point of the corrosion products and by the direct measurement of the surface interaction force between the corrosion products and Inconel 600. These measurements have served to support the hypothesis that adsorption of amine affects the magnetite deposition rate by lowering the force of repulsion between magnetite and the surface of Inconel 600. The deposition rate of hematite increased as the oxygen concentration increased. A mechanism to account for enhanced deposition rates at high mixture qualities (> 0.35) has been identified and shown to predict behaviour that is consistent with both experimental and plant data. As a result of this investigation, several criteria are proposed to reduce the extent of corrosion product deposition on the tube bundle. Low hematite deposition is favoured by a low concentration of dissolved oxygen, and low magnetite deposition is favoured by choosing an amine for pH control that has little tendency to adsorb onto the surface of magnetite. To minimize adsorption the amine should have a high base strength and a large 'footprint' on the surface of magnetite. To prevent enhanced deposition at high mixture qualities, it is proposed that a modified amine be used that will reduce the surface tension or the elasticity of the steam-water interface or both

  7. Multispectral imaging: an application to density measurement of photographic paper in the manufacturing process control

    Science.gov (United States)

    Shrestha, Raju; Hardeberg, Jon Yngve

    2015-02-01

    In this paper, we present an industrial application of multispectral imaging, for density measurement of colorants in photographic paper. We designed and developed a 9-band LED illumination based multispectral imaging system specifically for this application in collaboration with FUJIFILM Manufacturing Europe B.V., Tilburg, Netherlands. Unlike a densitometer, which is a spot density measurement device, the proposed system enables fast density measurement in a large area of a photo paper. Densities of the four colorants (CMYK) at every surface point in an image are calculated from the spectral reflectance image. Fast density measurements facilitate automatic monitoring of density changes (which is proportional to thickness changes), which helps control the manufacturing process for quality and consistent output. Experimental results confirm the effectiveness of the proposed system.

  8. Secondary side water chemistry pH control strategy improvements

    International Nuclear Information System (INIS)

    Over the years the PWR plant operators were aware of the need of optimizing the pH control strategy in the water-steam cycle with the focus on improvement of steam generator performance with the main goal of reducing the corrosion product ingress into the steam generators and their consequences: SG fouling, SG tube corrosion beneath deposits. To achieve this goal, it becomes necessary to harmonize three requirements: a. High overall pH along the circuit for suppression of general corrosion, requiring a volatile amine to ensure a suitable distribution in steam areas and condenser, and b. High local pH at the water phase of two-phase flow areas, requiring an either rather low volatile amine to ensure high pH in the wet steam water film, or larger amounts of a volatile amine. c. Sufficient amount of hydrazine to ensure reducing conditions in the steam generators. The basic strategy of AREVA NP GmbH (formerly KWU), successfully applied in German nuclear power plants since the late seventies consisted on the achievement of the necessary pH by means of ammonia, as generated by thermal decomposition of hydrazine. By dosing of hydrazine at the necessary amounts to ensure reducing conditions, also sufficient ammonia is generated to achieve a high overall pH along the cycle, being the target pH (25 deg. C) ≥ 9.8 resulting in < 1 ppb Fe in final feed water. This treatment is known as H-AVT (High pH - All Volatile Treatment). Main prerequisite for its application is to have a copper-free system. Eventually, H-AVT started to be applied later at some other western nuclear power plants. In some units, the high condenser exhaust flow rate applied caused a considerable amount of ammonia being removed from the cycle, resulting in too low ammonia concentrations to maintain a sufficiently high pH, making the addition of ammonia necessary. AREVA NP GmbH together with plant operators investigated the possibility of complementing the applied classical H-AVT by addition of an advanced

  9. Controlling Nonspecific Protein Adsorption in a Plug-Based Microfluidic System by Controlling Interfacial Chemistry Using Fluorous-Phase Surfactants

    OpenAIRE

    Roach, L. Spencer; Song, Helen; Ismagilov, Rustem F.

    2005-01-01

    Control of surface chemistry and protein adsorption is important for using microfluidic devices for biochemical analysis and high-throughput screening assays. This paper describes the control of protein adsorption at the liquid-liquid interface in a plug-based microfluidic system. The microfluidic system uses multiphase flows of immiscible fluorous and aqueous fluids to form plugs, which are aqueous droplets that are completely surrounded by fluorocarbon oil and do not come into direct contac...

  10. Control of radical chemistry in the AdoMet-radical enzymes

    Science.gov (United States)

    Duschene, Kaitlin S.; Veneziano, Susan E.; Silver, Sunshine C.; Broderick, Joan B.

    2009-01-01

    Summary The radical AdoMet superfamily comprises a diverse set of >2800 enzymes that utilize iron-sulfur clusters and S-adenosylmethionine (SAM or AdoMet) to initiate a diverse set of radical-mediated reactions. The intricate control these enzymes exercise over the radical transformations they catalyze is an amazing feat of elegance and sophistication in biochemistry. This review focuses on the accumulating evidence for how these enzymes control this remarkable chemistry, including controlling the reactivity between the iron-sulfur cluster and AdoMet, and controlling the subsequent radical transformations. PMID:19269883

  11. Control of radical chemistry in the AdoMet radical enzymes.

    Science.gov (United States)

    Duschene, Kaitlin S; Veneziano, Susan E; Silver, Sunshine C; Broderick, Joan B

    2009-02-01

    The radical AdoMet superfamily comprises a diverse set of >2800 enzymes that utilize iron-sulfur clusters and S-adenosylmethionine (SAM or AdoMet) to initiate a diverse set of radical-mediated reactions. The intricate control these enzymes exercise over the radical transformations they catalyze is an amazing feat of elegance and sophistication in biochemistry. This review focuses on the accumulating evidence for how these enzymes control this remarkable chemistry, including controlling the reactivity between the iron-sulfur cluster and AdoMet, and controlling the subsequent radical transformations. PMID:19269883

  12. Shop Floor-Level Control of Manufacturing Companies: An Interview Study in Finland

    Directory of Open Access Journals (Sweden)

    Tokola Henri

    2015-02-01

    Full Text Available This paper publishes the results of interviews regarding shop-floor-level control of 18 Finnish manufacturing companies. The interviews had 17 open questions relating to demand characteristics, shop floor-level control issues, production flexibility, inventory control, and potential development areas. In order to get insights from the interviews, this paper analyses the answers from the interviews and categorises them into typical answers. The companies that were interviewed are also categorised as small companies with their own end products, subcontractors, or large companies with their own end products, and the emphasis of the analysis is on how companies differ in their shop floor-level control. The results show that different types of companies have different characteristics. Small companies are characterised by constant workflow, seasonal trends in demand, and the use of forecasts. Subcontractors have great daily variation in their demand and processing times. Large companies tend to focus on inventory issues.

  13. Towards the implementation of e-manufacturing: design of an automatic tea drying control system

    Directory of Open Access Journals (Sweden)

    Mabvuu, Never

    2014-11-01

    Full Text Available Many of the production costs for producing tea are attributable to the process of drying the tea. E-manufacturing can assist companies to reduce these production costs by making crucial information available to decision-makers so that they can make informed decisions. This paper presents an application of e-manufacturing to the design of an automatic tea drying control system. This control system will ensure that the multiple drying parameters such as temperature, dryer-exit tea moisture content, and fuel consumption are maintained at optimal states during the course of the drying of tea. The additional aim of this system is to balance the cost of production and the quality of the final product. Using the Guggenheim-Anderson-De Boer (GAB model, the optimum drying temperature was found to be 100-110°C, while maintaining a dryer-exit tea moisture content of 3 to 3.12 per cent, at a drying rate of 3 per cent per minute. A Barix control application to control the system’s activities, using the web user interface (WUI, was also developed.

  14. APPLICATION OF IMPROVED PRODUCTION ACTIVITY CONTROL ARCHITECTURE FOR SHOP FLOOR INFORMATION SYSTEM IN DIGITAL MANUFACTURING

    Institute of Scientific and Technical Information of China (English)

    SHAHID Ikramullah Butt; SUN Houfang; GAO Zhengqing

    2006-01-01

    Shop floor control (SFC) is responsible for the coordination and control of the manufacturing physical and information flow within the shop floor in the manufacturing system. Weaknesses of the production activity control (PAC) architecture of the shop floor are addressed by the Maglica's new system architecture. This architecture gives rise to unlimited number of movers and producers thus evolving more complex but decentralized architecture. Beijing Institute of Technology - production activity control (BIT-PAC) architecture introduces an idea of sub-producers and sub-movers thus reducing the complexity of the architecture. All the equipments including sub-producers and sub-movers are considered to be passive in the proposed shop floor information system. The dissemination of information from sub-producers and sub-movers is done manually through a PC. Proposed BIT-PAC SFC architecture facilitates the information flow from shop floor to the other area of the organization. Effective use of internet information services (IIS) and SQL2000 is done along with the ASP. NET technology to implement the application logic. Applicability of the software based on BIT-PAC architecture is checked by running application software on a network PC that supports the dynamic flow of information from sub-producers and sub-movers to the other parts of the organization. Use of software is also shown at the end for BIT training workshop thus supporting the use of SFC architecture for similar kind of environments.

  15. Consideration of primary coolant chemistry control during PWR reactor trip period

    International Nuclear Information System (INIS)

    The chemistry of a PWR reactor coolant after plant shutdown and cooldown changes, from a slightly alkaline reducing phase during power operation, to an acidic reducing phase. Plant experiences have indicated that the shutdown chemistry control of reactor coolant could decrease localized high radiation levels and hence personnel exposures. While, it has not been easy to find any presentation of the shutdown chemistry control during a reactor trip. In this study, the primary coolant chemistry during the reactor trip period at a domestic PWR nuclear power plant A was thermodynamically evaluated. It was found out that, due to no subsequent acid-oxidizing process that should be followed after an acid-reducing step, the radiation dose rate in the steam generator chamber increased during the following end-cycle shutdown period. In an experimental study, the release of nickel from synthesized Ni0.6Fe2.4O4, which reacted with or without 30 cc/kg or 45 cc/kg of dissolved hydrogen in an aqueous solution containing 2000 ppm-B boric acid at 150degC for 2 hours, showed that in an acidic-only condition, established after degassing of dissolved hydrogen, it would be possible for nickel to be dissolved into the primary coolant at high temperatures. Considerations of a primary coolant chemistry control during the PWR reactor trip period were suggested as follows: In the case of shutdown and cooldown up to Mode 5 during a reactor trip, the early-boration, and maintaining dissolved hydrogen concentration and injecting hydrogen peroxide at 82degC would be desirable, in order to enhance reduction of nickel ferrite, oxidation of its decomposition products and removal of the dissolved ionic chemical species by purification. While in the case up to Mode 4, decreasing the dissolved hydrogen concentration would be better, in order to suppress the reduction of nickel ferrite. (author)

  16. FROM MANUFACTURING SCHEDULING TO SUPPLY CHAIN COORDINATION:THE CONTROL OF COMPLEXITY AND UNCERTAINTY

    Institute of Scientific and Technical Information of China (English)

    Peter B. LUH; Weidong FENG

    2003-01-01

    With time-based competition and rapid technology advancements, effective manufacturing scheduling and supply chain coordination are critical to quickly respond to changing market conditions. These problems, however, are difficult in view of inherent complexity and various uncertainties involved. Based on a series of results by the authors, decomposition and coordination by using Lagrangian relaxation is identified in this paper as an effective way to control complexity and uncertainty. A manufacturing scheduling problem is first formulated within the job shop context with uncertain order arrivals, processing times, due dates, and part priorities as a separable optimization problem. A solution methodology that combines Lagrangian relaxation, stochastic dynamic programming, and heuristics is developed. Method improvements to effectively solve large problems are also highlighted. To extend manufacturing scheduling within a factory to coordinate autonomic members across chains of suppliers, a decentralized supply chain model is established in the second half of this paper. By relaxing cross-member constraints, the model is decomposed into member-wise subproblems, and a nested optimization structure is developed based on the job shop scheduling results. Coordination is performed through the iterative updating of cross-member prices without accessing other members' private information or intruding their decision-making authorities, either with or without a coordinator. Two examples are presented to demonstrate the effectiveness of the method. Future prospects to overcome problem inseparability and improve computing efficiency are then discussed.

  17. A model of quality control based on recycling economy and sustainable manufacture

    Institute of Scientific and Technical Information of China (English)

    Chen Xiangyu; Liang Gongqian; Ma Shining

    2006-01-01

    People currently pay attention to a hotspot problem that how industrial production is evaluated and controlled based on sustainable development theory. Quality is one of the important indexes. Two mainstream theories guide us to realize the industrial sustainable development,: mainly the circular economy and sustainable manufacturing are introduced.The basic characteristics of the sustainable manufacturing are introduced, and that quality management is important contents of sustainable development is indicated. Based on circular economy and sustainable manufacture theories, the drawbacks in the existing quality management models are analyzed. The requests that satisfy the big system "environment - society - economy" are summarized to build up a model. A Chinese traditional cultural principle is applied and the relevant contents are sublimated as the platform to set up the model. The new quality management concept models are put forward "T- D- R" three-dimensional structures and "ecological quality loop" model, from which the new quality concepts are formed. The paper elaborates the contents and the process of setting up the models. The big quality problems of the system can be handled by the new quality concept and model that are validated in practice.

  18. The NC (numerically controlled) assistant: Interfacing knowledge based manufacturing tools to CAD/CAM systems

    Energy Technology Data Exchange (ETDEWEB)

    Burd, W.C.

    1988-01-01

    A knowledge based computer program that assists programmers of numerically controlled (NC) machine tools is described. The program uses part features identified by the NC programmer and a set of expert system manufacturing rules to select cutting parameters and produce NC part programs. An expert system shell determines the NC sequence and the machining parameters. Several point-to-point NC functions are currently in production. A CAD/CAM system interface for milling and turning functions is also described. 2 refs., 24 figs.

  19. Closed vessel technique for assessment of ballistic characteristics in quality control of propellant manufacture

    Directory of Open Access Journals (Sweden)

    G. Siva Ramakrishnan

    1958-07-01

    Full Text Available "In order to assess the ballistic performance of a propellant it is necessary to measure its following characteristics: (aForce constant, (bvivacity, and (cshape. It is possible to determine (aand (bby the closed vessel technique which enables ballistic performance of the propellant in the gun to be estimated. It can be very usefully employed for quality control of propellant manufacture. As more and more experience is gained in the closed vessel technique these tests have several other possible practical applications such as those: (afor inspection of propellants, (bfor assessment of quality, (c to reduce proof in guns, and (dto check ballistics of a lot after long storage."

  20. Compliance and control characteristics of an additive manufactured-flexure stage

    International Nuclear Information System (INIS)

    This paper presents a compliance and positioning control characteristics of additive manufactured-nanopositioning system consisted of the flexure mechanism and voice coil motor (VCM). The double compound notch type flexure stage was designed to utilize the elastic deformation of two symmetrical four-bar mechanisms to provide a millimeter-level working range. Additive manufacturing (AM) process, stereolithography, was used to fabricate the flexure stage. The AM stage was inspected by using 3D X-ray computerized tomography scanner: air-voids and shape irregularity. The compliance, open-loop resonance peak, and damping ratio of the AM stage were measured 0.317 mm/N, 80 Hz, and 0.19, respectively. The AM stage was proportional-integral-derivative positioning feedback-controlled and the capacitive type sensor was used to measure the displacement. As a result, the AM flexure mechanism was successfully 25 nm positioning controlled within 500 μm range. The resonance peak was found approximately at 280 Hz in closed-loop. This research showed that the AM flexure mechanism and the VCM can provide millimeter range with high precision and can be a good alternative to an expensive metal-based flexure mechanism and piezoelectric transducer

  1. Compliance and control characteristics of an additive manufactured-flexure stage

    Energy Technology Data Exchange (ETDEWEB)

    Lee, ChaBum; Tarbutton, Joshua A. [Department of Mechanical Engineering, University of South Carolina, 300 Main St., Columbia, South Carolina 29208 (United States)

    2015-04-15

    This paper presents a compliance and positioning control characteristics of additive manufactured-nanopositioning system consisted of the flexure mechanism and voice coil motor (VCM). The double compound notch type flexure stage was designed to utilize the elastic deformation of two symmetrical four-bar mechanisms to provide a millimeter-level working range. Additive manufacturing (AM) process, stereolithography, was used to fabricate the flexure stage. The AM stage was inspected by using 3D X-ray computerized tomography scanner: air-voids and shape irregularity. The compliance, open-loop resonance peak, and damping ratio of the AM stage were measured 0.317 mm/N, 80 Hz, and 0.19, respectively. The AM stage was proportional-integral-derivative positioning feedback-controlled and the capacitive type sensor was used to measure the displacement. As a result, the AM flexure mechanism was successfully 25 nm positioning controlled within 500 μm range. The resonance peak was found approximately at 280 Hz in closed-loop. This research showed that the AM flexure mechanism and the VCM can provide millimeter range with high precision and can be a good alternative to an expensive metal-based flexure mechanism and piezoelectric transducer.

  2. Compliance and control characteristics of an additive manufactured-flexure stage.

    Science.gov (United States)

    Lee, ChaBum; Tarbutton, Joshua A

    2015-04-01

    This paper presents a compliance and positioning control characteristics of additive manufactured-nanopositioning system consisted of the flexure mechanism and voice coil motor (VCM). The double compound notch type flexure stage was designed to utilize the elastic deformation of two symmetrical four-bar mechanisms to provide a millimeter-level working range. Additive manufacturing (AM) process, stereolithography, was used to fabricate the flexure stage. The AM stage was inspected by using 3D X-ray computerized tomography scanner: air-voids and shape irregularity. The compliance, open-loop resonance peak, and damping ratio of the AM stage were measured 0.317 mm/N, 80 Hz, and 0.19, respectively. The AM stage was proportional-integral-derivative positioning feedback-controlled and the capacitive type sensor was used to measure the displacement. As a result, the AM flexure mechanism was successfully 25 nm positioning controlled within 500 μm range. The resonance peak was found approximately at 280 Hz in closed-loop. This research showed that the AM flexure mechanism and the VCM can provide millimeter range with high precision and can be a good alternative to an expensive metal-based flexure mechanism and piezoelectric transducer. PMID:25933897

  3. Haze defect control and containment in a high volume DRAM manufacturing environment

    Science.gov (United States)

    Chen, Jerry X.; Nguyen, Maihan; Arasaki, Osamu; Maraquin, Tammy; Sawyer, Daniel; Morrison, Pedro

    2005-11-01

    Haze and other progressive reticle defects have been known in the semiconductor industry for more than a decade [1]. Extensive research and experiments have been carried out to determine the sources and origins of the progressive haze growth, but the true mechanisms of its cause are still under speculation. To minimize the wafer yield loss at Samsung Austin Semiconductor (SAS), we introduced a practical method to control the haze defects in a DRAM manufacturing environment that integrates reticle and wafer inspections, reticle cleaning, and a dose-based and time-based control forecast software system. This development has been proven to be very effective in controlling the haze defects and reducing the related yield loss while still supporting high volume wafer production.

  4. Water chemistry control for the target/blanket region of the accelerator production of tritium

    International Nuclear Information System (INIS)

    High-energy particle interactions in the various components of the target/blanket region of the Accelerator Production of Tritium lead to heat generation and deposition. Heavy-water and light-water systems are used to cool the target/blanket system and associated equipment. Structural materials include Inconel alloy 718, aluminum-clad lead rods, aluminum tubes containing helium-3 and tritium gas, and stainless steel components. Proper coolant chemistry is required to maximize neutron production, minimize corrosion of components, and minimize activity buildup. Corrosion-related phenomena and development of coolant and moderator corrosion control for both power and defense fission reactors has been studied extensively over the past 50 years. Less is known, however, about cooling systems for accelerators where a variety of transient chemical species and spallation products may be formed. The following provides a discussion on the issues that need to be addressed for proper water chemistry control for the APT system

  5. Spatially controlled immobilisation of biomolecules: A complete approach in green chemistry

    Science.gov (United States)

    Grinenval, Eva; Nonglaton, Guillaume; Vinet, Françoise

    2014-01-01

    The development of 'green' sensors is a challenging task in the field of biomolecule sensing, for example in the detection of cardiac troponin-I (cTnI). In the present work a complete approach in green chemistry was developed to create chemically active patterns for the immobilisation of biological probes. This key technology is discussed on the basis of the twelve green chemistry principles, and is a combination of surface patterning by spotting and surface chemistries modified by molecular vapour deposition. The (1H,1H,2H,2H)-perfluorodecyltrichlorosilane (FDTS) was used as a novel anti-adsorption layer while the 3,4-epoxybutyltrimethoxysilane (EBTMOS) was used to immobilise probes. Oligonucleotides and the anti-cTnI antibody were studied. The spatially controlled immobilisation of probes was characterised by fluorescence. The demonstrated surface modification has broad applications in areas such as diagnostics and bio-chemical sensing. Moreover, the environmental impacts of surface patterning and surface chemistry were discussed from a 'greenness' point of view.

  6. Characterization and control of dynamic lens heating effects under high volume manufacturing conditions

    Science.gov (United States)

    Bekaert, J.; Van Look, L.; Vandenberghe, G.; van Adrichem, P.; Maslow, M. J.; Gemmink, J.-W.; Cao, H.; Hunsche, S.; Neumann, J. T.; Wolf, A.

    2011-04-01

    The desire to reduce cost in volume manufacturing has driven up the throughput in the lithographic exposure machines. As a result the power transmitted in the projection optics increases. Although small, the absorption levels in the lens materials are not zero, which leads to localized heating of the lens and hence lens aberrations. To squeeze out the maximum process windows, the pupil shapes have transformed from simple annular shapes to shapes with very concentrated poles. As a result, the exposure energy transported through the lens is no longer equally distributed over the lenses of the projection options. Instead only a fraction of the lens gets to transport the total power. This concentration of power further aggravates the lens heating induced aberrations and enhances the importance of advanced lens heating control schemes which are available on ASML scanners. To analyze the effects of lens heating on the final imaging, a model was developed by the lens manufacturer Carl Zeiss SMT GmbH, and incorporated into a litho simulation environment by ASML BRION. This tool can be used to analyze the impact of dose/throughput, illumination shapes and reticle layout on aberrations. It provides a means to assess potential lens heating issues even before production masks are manufactured. Moreover, this computational tool opens the possibility to calculate parameters for lens heating correction, rather than measuring them, saving valuable machine time. In this paper, the performance of the novel computational lens heating control is demonstrated on wafer and compared with the traditional way of measuring the relevant parameters. In addition, a modeling study is performed to assess possible lens heating effects for freeform or non-traditional source shapes, thereby demonstrating the advanced correction potential of ASML latest aberration manipulator, called FlexWaveTM.

  7. Automation system for quality control in manufacture of iodine-125 sealed sources used in brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Somessari, Samir L.; Feher, Anselmo; Sprenger, Francisco E.; Rostellato, Maria E.C.M.; Moura, Joao A.; Costa, Osvaldo L.; Calvo, Wilson A.P., E-mail: somessar@ipen.b, E-mail: afeher@ipen.b, E-mail: sprenger@ipen.b, E-mail: elisaros@ipen.b, E-mail: olcosta@ipen.b, E-mail: wapcalvo@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The objective of this work is to develop an automation system for Quality Control in the production of Iodine-125 sealed sources, after undergoing the process of laser beam welding. These sources, also known as Iodine-125 seeds are used, successfully, in the treatment of cancer by brachytherapy, with low-dose rates. Each small seed is composed of a welded titanium capsule with 0.8 mm diameter and 4.5 mm in length, containing Iodine-125 adsorbed on an internal silver wire. The seeds are implanted in the human prostate to irradiate the tumor and treat the cancerous cells. The technology to automate the quality control system in the manufacture of Iodine-125 seeds consists in developing and associate mechanical parts, electronic components and pneumatic circuits to control machines and processes. The automation technology for Iodine-125 seed production developed in this work employs programmable logic controller, step motors, drivers of control, electrical-electronic interfaces, photoelectric sensors, interfaces of communication and software development. Industrial automation plays an important role in the production of Iodine-125 seeds, with higher productivity and high standard of quality, facilitating the implementation and operation of processes with good manufacturing practices. Nowadays, the Radiation Technology Center at IPEN-CNEN/SP imports and distributes 36,000 Iodine-125 seeds per year for clinics and hospitals in the whole country. However, the Brazilian potential market is of 8,000 Iodine-125 seeds per month. Therefore, the local production of these radioactive seeds has become a priority for the Institute, aiming to reduce the price and increase the supply to the population in Brazil. (author)

  8. Automation system for quality control in manufacture of iodine-125 sealed sources used in brachytherapy

    International Nuclear Information System (INIS)

    The objective of this work is to develop an automation system for Quality Control in the production of Iodine-125 sealed sources, after undergoing the process of laser beam welding. These sources, also known as Iodine-125 seeds are used, successfully, in the treatment of cancer by brachytherapy, with low-dose rates. Each small seed is composed of a welded titanium capsule with 0.8 mm diameter and 4.5 mm in length, containing Iodine-125 adsorbed on an internal silver wire. The seeds are implanted in the human prostate to irradiate the tumor and treat the cancerous cells. The technology to automate the quality control system in the manufacture of Iodine-125 seeds consists in developing and associate mechanical parts, electronic components and pneumatic circuits to control machines and processes. The automation technology for Iodine-125 seed production developed in this work employs programmable logic controller, step motors, drivers of control, electrical-electronic interfaces, photoelectric sensors, interfaces of communication and software development. Industrial automation plays an important role in the production of Iodine-125 seeds, with higher productivity and high standard of quality, facilitating the implementation and operation of processes with good manufacturing practices. Nowadays, the Radiation Technology Center at IPEN-CNEN/SP imports and distributes 36,000 Iodine-125 seeds per year for clinics and hospitals in the whole country. However, the Brazilian potential market is of 8,000 Iodine-125 seeds per month. Therefore, the local production of these radioactive seeds has become a priority for the Institute, aiming to reduce the price and increase the supply to the population in Brazil. (author)

  9. Hierarchical tailoring of strut architecture to control permeability of additive manufactured titanium implants

    International Nuclear Information System (INIS)

    Porous titanium implants are a common choice for bone augmentation. Implants for spinal fusion and repair of non-union fractures must encourage blood flow after implantation so that there is sufficient cell migration, nutrient and growth factor transport to stimulate bone ingrowth. Additive manufacturing techniques allow a large number of pore network designs. This study investigates how the design factors offered by selective laser melting technique can be used to alter the implant architecture on multiple length scales to control and even tailor the flow. Permeability is a convenient parameter that characterises flow, correlating to structure openness (interconnectivity and pore window size), tortuosity and hence flow shear rates. Using experimentally validated computational simulations, we demonstrate how additive manufacturing can be used to tailor implant properties by controlling surface roughness at a microstructual level (microns), and by altering the strut ordering and density at a mesoscopic level (millimetre). Highlights: • Experimentally validated permeability prediction tools for hierarchical implants. • Randomised structures form preferential flow channels with stronger shear flows. • Hierarchical strut structures allow independent tailoring of flow and pore size

  10. SISTEM PENDUKUNG KEPUTUSAN PENERIMAAN PESANAN MENGGUNAKAN LOAD ORIENTED MANUFACTURING CONTROL (LOMC

    Directory of Open Access Journals (Sweden)

    Deni Pandwinata

    2013-06-01

    Full Text Available CV. Grafika Inndah is a printing company, majoring in job order production system. While so far, the company has problems on the decision making due to lead time for booking orders that the company can accept customer orders according to quantity and due date.  The production process of the design, print finishing and that includes the print engine 52 and engine Sakura print shop.  The station receives a print job that exceeds the load capacity. Thus this research aims to determine the lead time, the average output and average utility.  Data processing in this study using the method of manufacturing systems based load control (load oriented manufacturing control, and to assist in decision-making applications built using Delphi.  Programming of the analysis of the data processing method known LOMC can the average lead time work station 2.88 hours and an average of 99.7% utilities, and Print Shop Lead time average of 1.82 hours and an average of 99.85% utilities. Decision support system applied in this study deserves to be implemented.  It can be seen from the test program using the Black Box Test and Alpha Test is evidenced in respondents answered SS (strongly agree as much as 48% and S (agree as much as 46% .

  11. Hierarchical tailoring of strut architecture to control permeability of additive manufactured titanium implants

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Z. [Department of Materials, Imperial College London, South Kensington Campus, London, SW7 2AZ (United Kingdom); Jones, D. [School of Engineering, University of Liverpool, Brownlow Hill, Liverpool, L69 3GH (United Kingdom); Yue, S. [Manchester X-ray Imaging Facility, School of Materials, The University of Manchester, Oxford Road, M13 9PL (United Kingdom); Lee, P.D., E-mail: peter.lee@manchester.ac.uk [Manchester X-ray Imaging Facility, School of Materials, The University of Manchester, Oxford Road, M13 9PL (United Kingdom); Jones, J.R. [Department of Materials, Imperial College London, South Kensington Campus, London, SW7 2AZ (United Kingdom); Sutcliffe, C.J. [School of Engineering, University of Liverpool, Brownlow Hill, Liverpool, L69 3GH (United Kingdom); Jones, E. [Department of Advanced Technology, Stryker Orthopaedics, Raheen Business Park, Limerick (Ireland)

    2013-10-15

    Porous titanium implants are a common choice for bone augmentation. Implants for spinal fusion and repair of non-union fractures must encourage blood flow after implantation so that there is sufficient cell migration, nutrient and growth factor transport to stimulate bone ingrowth. Additive manufacturing techniques allow a large number of pore network designs. This study investigates how the design factors offered by selective laser melting technique can be used to alter the implant architecture on multiple length scales to control and even tailor the flow. Permeability is a convenient parameter that characterises flow, correlating to structure openness (interconnectivity and pore window size), tortuosity and hence flow shear rates. Using experimentally validated computational simulations, we demonstrate how additive manufacturing can be used to tailor implant properties by controlling surface roughness at a microstructual level (microns), and by altering the strut ordering and density at a mesoscopic level (millimetre). Highlights: • Experimentally validated permeability prediction tools for hierarchical implants. • Randomised structures form preferential flow channels with stronger shear flows. • Hierarchical strut structures allow independent tailoring of flow and pore size.

  12. Interoperability for Space Mission Monitor and Control: Applying Technologies from Manufacturing Automation and Process Control Industries

    Science.gov (United States)

    Jones, Michael K.

    1998-01-01

    Various issues associated with interoperability for space mission monitor and control are presented in viewgraph form. Specific topics include: 1) Space Project Mission Operations Control Architecture (SuperMOCA) goals and methods for achieving them; 2) Specifics on the architecture: open standards ad layering, enhancing interoperability, and promoting commercialization; 3) An advertisement; 4) Status of the task - government/industry cooperation and architecture and technology demonstrations; and 5) Key features of messaging services and virtual devices.

  13. The effects of coolant chemistry control and fuel management strategies on fuel cladding corrosion

    International Nuclear Information System (INIS)

    A corrosion model has been developed that describes the in-pile corrosion of Zircaloy-4 fuel cladding irradiated in commercial pressurized water reactors. The model is used to quantify the effects of coolant chemistry control and fuel management strategies on the end-of-life cladding corrosion thickness. Corrosion data were obtained from autoclave experiments and from over 500 fuel rods irradiated in 14 different commercial reactors with varying duties and coolant chemistry control strategies. Data were obtained for both Conventional and Improved Zircaloy-4. Oxide thickness ranged from 5 microns to over 130 microns on fuel rods with burnups up to 60,000 MWD/MTU. Corrosion data were selected from along the lengths of the irradiated rods and were combined with the local thermal/hydraulic and coolant chemistry conditions to construct a corrosion database. More than 2800 data points were included in the database. In-pile corrosion rates were found to be higher than out-of-pile thermal corrosion rates. Studies were performed to identify the parameters that caused the increase, and it was determined that lithium concentration, fast neutron flux, oxide layer thickness, boiling rates and the tin level in the cladding affected the corrosion rates. An empirical model was developed to correlate the in-pile corrosion data with rate enhancement factors used as multipliers on the thermal corrosion rate. (UK)

  14. Effect of global climate change on forest productivity: Control through forest floor chemistry

    International Nuclear Information System (INIS)

    Forest floor chemistry interacts with temperature and moisture to restrict or enhance the supply of nutrients for tree growth. In sub-arctic forests of interior Alaska, this control of element supply is manifest in dramatically different rates of nutrient cycling among the principal forest types. Slow-growing forests developing on cold, wet soils produce organic detritus that is slow to decompose because of its chemical composition. Consequently, element supply is restricted in these ecosystems. Productive forests developing on warm, drier soils produce organic detritus that decays more rapidly because of favorable chemical composition. Element supply is enhanced in these forest ecosystems. Using the compartment model Linkages, the authors evaluate several scenarios that propose altered temperature and precipitation regimes for their influence on forest floor chemistry, element supply and the consequence to forest productivity

  15. Dominant processes controlling water chemistry of the Pecos River in American southwest

    Science.gov (United States)

    Yuan, Fasong; Miyamoto, Seiichi

    2005-09-01

    Here we show an analysis of river flow and water chemistry data from eleven gauging stations along the Pecos River in eastern New Mexico and western Texas, with time spanning 1959-2002. Analysis of spatial relationship between the long-term average flow and total dissolved solids (TDS) concentration allows us to illuminate four major processes controlling river chemistry, namely saline water addition, evaporative concentration with salt gain or loss, dilution with salt gain or loss, and salt storage. Of the 10 river reaches studied, six reaches exhibit the process dominated by evaporative concentration or freshwater dilution with little change in salt load. Four reaches show considerable salt gains or losses that are induced by surface-ground water interactions. This analysis suggests that the evaporative concentration and freshwater dilution are the prevailing mechanisms, but local processes (e.g., variations in hydrologic flowpath and lithologic formation) also play an important role in regulating the hydrochemistry of the Pecos River.

  16. Best possible cycle chemistry control in steam turbine plants; Baesta moejliga oevervakning av vattenkemin i anlaeggningar med aangturbin

    Energy Technology Data Exchange (ETDEWEB)

    Hellman, Mats [Hellman Vatten AB, Stockholm (Sweden)

    2004-11-01

    A project has been conducted of a large number of power and pulp plants in Sweden. Production managers and those responsible for water quality control were visited and interviewed. In addition, a research of cycle chemistry literature has been conducted to determine what has been done in other countries. The review of this literature shows that the Electric Power Research Institute in the USA and ESKOM in South Africa are in the forefront regarding QA/QC and have come a long way in water control management. A key requirement for successful plant cycle chemistry is corporate management support. The project makes it clear that cycle chemistry control was best at plants where production management was aware of the importance of high water quality. There is a real need for feed water technique and water quality education at all company levels. The objective should be that 'everyone should know the importance of right water quality'. Personnel without an education in chemistry often regard cycle chemistry as somewhat complicated. Better understanding and better working cycle chemistry control can be obtained by making the control easier and clearer for persons without training in chemistry. Extensive on-line instrumentation with well-designed systems for presenting the data, by-far, gives the best cycle chemistry control. It is important to have a holistic view when water treatment systems and on-line instrumentation are planned. It is not the amount of instruments or the number of chemistry personnel that is important. The important thing is to ensure that all functions needed fit together in the best way possible. Today, when cycle chemistry monitoring is heavily dependent on on-line instrumentation, the reliability of the instruments is crucial. Therefore, it is important to have well-established routines for maintenance, calibration and service. In order to decrease forced outages of plants due to poor cycle chemistry, the focus of chemistry control should

  17. The use of interactive computer vision and robot hand controllers for enhancing manufacturing safety

    Science.gov (United States)

    Marzwell, Neville I.; Jacobus, Charles J.; Peurach, Thomas M.; Mitchell, Brian T.

    1994-01-01

    Current available robotic systems provide limited support for CAD-based model-driven visualization, sensing algorithm development and integration, and automated graphical planning systems. This paper describes ongoing work which provides the functionality necessary to apply advanced robotics to automated manufacturing and assembly operations. An interface has been built which incorporates 6-DOF tactile manipulation, displays for three dimensional graphical models, and automated tracking functions which depend on automated machine vision. A set of tools for single and multiple focal plane sensor image processing and understanding has been demonstrated which utilizes object recognition models. The resulting tool will enable sensing and planning from computationally simple graphical objects. A synergistic interplay between human and operator vision is created from programmable feedback received from the controller. This approach can be used as the basis for implementing enhanced safety in automated robotics manufacturing, assembly, repair and inspection tasks in both ground and space applications. Thus, an interactive capability has been developed to match the modeled environment to the real task environment for safe and predictable task execution.

  18. Process Control Strategies for Dual-Phase Steel Manufacturing Using ANN and ANFIS

    Science.gov (United States)

    Vafaeenezhad, H.; Ghanei, S.; Seyedein, S. H.; Beygi, H.; Mazinani, M.

    2014-11-01

    In this research, a comprehensive soft computational approach is presented for the analysis of the influencing parameters on manufacturing of dual-phase steels. A set of experimental data have been gathered to obtain the initial database used for the training and testing of both artificial neural networks (ANN) and adaptive neuro-fuzzy inference system (ANFIS). The parameters used in the strategy were intercritical annealing temperature, carbon content, and holding time which gives off martensite percentage as an output. A fraction of the data set was chosen to train both ANN and ANFIS, and the rest was put into practice to authenticate the act of the trained networks while seeing unseen data. To compare the obtained results, coefficient of determination and root mean squared error indexes were chosen. Using artificial intelligence methods, it is not necessary to consider and establish a preliminary mathematical model and formulate its affecting parameters on its definition. In conclusion, the martensite percentages corresponding to the manufacturing parameters can be determined prior to a production using these controlling algorithms. Although the results acquired from both ANN and ANFIS are very encouraging, the proposed ANFIS has enhanced performance over the ANN and takes better effect on cost-reduction profit.

  19. Intelligent manufacturing system of impeller for computer numerical control (CNC) programming based on KBE

    Institute of Scientific and Technical Information of China (English)

    王凌云; 黄红辉; 王大中

    2014-01-01

    To solve the problem of advanced digital manufacturing technology in the practical application, a knowledge engineering technology was introduced into the computer numerical control (CNC) programming. The knowledge acquisition, knowledge representation and reasoning used in CNC programming were researched. The CNC programming system functional architecture of impeller parts based on knowledge based engineering (KBE) was constructed. The structural model of the general knowledge-based system (KBS) was also constructed. The KBS of CNC programming system was established through synthesizing database technology and knowledge base theory. And in the context of corporate needs, based on the knowledge-driven manufacturing platform (i.e. UG CAD/CAM), VC++6.0 and UG/Open, the KBS and UG CAD/CAM were integrated seamlessly and the intelligent CNC programming KBE system for the impeller parts was developed by integrating KBE and UG CAD/CAM system. A method to establish standard process templates was proposed, so as to develop the intelligent CNC programming system in which CNC machining process and process parameters were standardized by using this KBE system. For the impeller parts processing, the method applied in the development of the prototype system is proven to be viable, feasible and practical.

  20. Controlled Thermal-Mechanical Processing of Tubes and Pipes for Enhanced Manufacturing and Performance

    Energy Technology Data Exchange (ETDEWEB)

    Kolarik, Robert V.

    2005-11-11

    The Alloy Steel Business of The Timken Company won an award for the controlled thermo-mechanical processing (CTMP) project and assembled a strong international public/private partnership to execute the project. The premise of the CTMP work was to combine Timken's product understanding with its process expertise and knowledge of metallurgical and deformation fundamentals developed during the project to build a predictive process design capability. The CTMP effort succeeded in delivering a pc-based capability in the tube optimization model, with a virtual pilot plant (VPP) feature to represent the desired tube making process to predict the resultant microstructure tailored for the desired application. Additional tasks included a system for direct, online measurement of grain size and demonstration of application of CTMP via robotically enhanced manufacturing.

  1. Supramolecular and heterosupramolecar chemistry in controlled release and molecular recognition processes

    OpenAIRE

    Agostini, Alessandro

    2013-01-01

    La presente tesis doctoral titulada ¿Supramolecular and heterosupramolecular chemistry in controlled release and molecular recognition processes¿ está centrada en los dos aspectos principales de la química supramolecular que han experimentado un gran auge en los últimos años: el reconocimiento molecular y los procesos de liberación controlada. En particular la primera parte de la tesis se focaliza en el diseño y síntesis de moléculas orgánicas que pueden ser empleados cómo...

  2. Processes controlling groundwater chemistry and identification of water resource vulnerability: Yarra catchment, Victoria

    International Nuclear Information System (INIS)

    Full text: Assessment of processes controlling groundwater chemistry is essential for water resource management and identification of water resource vulnerability. The Yarra Catchment (4045 km2) extends 120 km east of Melbourne and is considered a significant area for Melbourne's water resources. This catchment is characterised by fractured rock aquifers, a high baseflow component, high, localised recharge, and diverse land use. Therefore, identification of processes controlling groundwater chemistry is important for determining areas where groundwater, and inevitably surface water, are most vulnerable to contamination. The regional groundwater flow system is affected by high, localised recharge in areas of high surface elevations. Hence, a local groundwater flow system is investigated in detail to aid regional interpretation. Processes causing spatial heterogeneity of groundwater chemistry include the extent of recharge, water-rock interaction and land use processes. At high surface elevations Na:CI = 1, and direct recharge of precipitation into sedimentary or granitic aquifers results in groundwater with lower TDS values (∼ 50 to 100 mg/L), compared to groundwater where precipitation directly recharges younger basaltic aquifers (TDS ∼ 100 to 150 mg/L). At lower surface elevations Na:CI ratios decrease, and major ion concentrations, pH and TDS are significantly higher (TDS ∼ 400 to 500 mg/L) reflecting cumulative effects of water-rock interaction and agricultural land use lower in the catchment. Groundwater samples were also analysed for stable isotopes, the 180 and 2H values (-6.2 to 5.50, and -38.1 to 32.20 VSMOW respectively) lie on the Melbourne Meteoric Water Line, indicating that groundwater has not been subjected to evaporation or high-temperature water rock interaction. Slightly lower 180 and 2H values for groundwater compared to nearby surface water indicates that recharge of colder rains occurs preferentially, both on local and more regional scales

  3. The current state of development works for manufacturing and methods of controlling the nuclear fuel for NPPs of Ukraine

    International Nuclear Information System (INIS)

    The paper presents the results of NSC KIPT researches on manufacturing the fuel microspheres and pellets based on uranium dioxide. The data on fuel characteristics for different manufacturing stages are given. The problems of improving the fuel quality with changing the structure characteristics of pellets are considered. Demonstrated is the hardware for pellet controlling and presented are the new ways for developing the methods of controlling the nuclear fuel: X-ray fluorescent analysis; complex of nuclear-physical methods on the base of accelerators; laser-excitation energy-mass-spectrometer. (author)

  4. Technetium chemistry

    International Nuclear Information System (INIS)

    Technetium chemistry is a young and developing field. Despite the limited knowledge of its chemistry, technetium is the workhorse for nuclear medicine. Technetium is also a significant environmental concern because it is formed as a byproduct of nuclear weapons production and fission-power generators. Development of new technetium radio-pharmaceuticals and effective environmental control depends strongly upon knowledge of basic technetium chemistry. The authors performed research into the basic coordination and organometallic chemistry of technetium and used this knowledge to address nuclear medicine and environmental applications. This is the final report of a three-year Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL)

  5. Designing And Manufacture Of The Automatic Temperature Controller For Azeotropic Distillation Apparatus

    International Nuclear Information System (INIS)

    OH process analysis; distillation time stability for the two systems is 6 hours or 8 hours depending on the parameter settings for the current percentage of the BTA. Purpose: Designed and manufactured automatic temperature controller for distillation apparatus which enriched radioisotopes in studying produced water in the oilfield, can establish temperature for each different distillation procedures with an error of ± 1oC. (author)

  6. Controlled experimental aquarium system for multi-stressor investigation: carbonate chemistry, oxygen saturation, and temperature

    Directory of Open Access Journals (Sweden)

    E. E. Bockmon

    2013-02-01

    Full Text Available As the field of ocean acidification has grown, researchers have increasingly turned to laboratory experiments to understand the impacts of increased CO2 on marine organisms. However, other changes such as ocean warming and deoxygenation are occurring concurrently with the increasing CO2 concentrations, complicating the anthropogenic impact on organisms. This experimental aquarium design allows for independent regulation of CO2 concentration, O2 levels, and temperature in a controlled environment to study the impacts of multiple stressors. The system has the flexibility for a wide range of treatment chemistry, seawater volumes, and study organisms. Control of the seawater chemistry is achieved by equilibration of a chosen gas mixture with seawater using a Liqui-Cel® membrane contactor. Included as examples, two experiments performed using the system have shown control of CO2 between approximately 500–1400 μatm and O2 from 80–240 μmol kg−1. Temperature has been maintained to 0.5 °C or better in the range of 10–17 °C. On a weeklong timescale, control results in variability in pH of less than 0.007 pH units and in oxygen concentration less than 3.5 μmol kg−1. Longer experiments, over a month, have been completed with reasonable but lessened control, still better than 0.08 pH units and 13 μmol kg−1 O2. The ability to study the impacts of multiple stressors in the laboratory simultaneously, as well as independently, will be an important part of understanding the response of marine organisms to a high-CO2 world.

  7. Occupational hazards control of hazardous substances in clean room of semiconductor manufacturing plant using CFD analysis.

    Science.gov (United States)

    Li, Jianfeng; Zhou, Ya-Fei

    2015-02-01

    The manufacturing processes in chip industries are complex, and many kinds of raw materials and solvents of different nature are used, most of which are highly toxic and dangerous. During the machine preventive maintenance period, these toxic and harmful substances will escape from the sealed reaction chamber to the clean workshop environment and endanger the health of the workers on-site, resulting in occupational diseases. From the perspective of prevention, the spread and prediction of hydrochloric acid (HCl) that escaped from the metal-etching chamber during maintenance were studied in this article. The computational fluid dynamics technology was used for a three-dimensional numerical simulation of the indoor air velocity field and the HCl concentration field, and the simulation results were then compared with the on-site monitoring data to verify the correctness and feasibility. The occupational hazards and control measures were analyzed based on the numerical simulation, and the optimal control measure was obtained. In this article, using the method of ambient air to analyze the occupational exposure can provide a new idea to the field of occupational health research in the integrated circuit industry and had theoretical and practical significance. PMID:23293134

  8. Active edge control in the precessions polishing process for manufacturing large mirror segments

    Science.gov (United States)

    Li, Hongyu; Zhang, Wei; Walker, David; Yu, Gouyo

    2014-09-01

    The segmentation of the primary mirror is the only promising solution for building the next generation of ground telescopes. However, manufacturing segmented mirrors presents its own challenges. The edge mis-figure impacts directly on the telescope's scientific output. The `Edge effect' significantly dominates the polishing precision. Therefore, the edge control is regarded as one of the most difficult technical issues in the segment production that needs to be addressed urgently. This paper reports an active edge control technique for the mirror segments fabrication using the Precession's polishing technique. The strategy in this technique requires that the large spot be selected on the bulk area for fast polishing, and the small spot is used for edge figuring. This can be performed by tool lift and optimizing the dell time to compensate for non-uniform material removal at the edge zone. This requires accurate and stable edge tool influence functions. To obtain the full tool influence function at the edge, we have demonstrated in previous work a novel hybrid-measurement method which uses both simultaneous phase interferometry and profilometry. In this paper, the edge effect under `Bonnet tool' polishing is investigated. The pressure distribution is analyzed by means of finite element analysis (FEA). According to the `Preston' equation, the shape of the edge tool influence functions is predicted. With this help, the multiple process parameters at the edge zone are optimized. This is demonstrated on a 200mm crosscorners hexagonal part with a result of PV less than 200nm for entire surface.

  9. PENGENDALIAN LANTAI PABRIK DENGAN LOAD ORIENTED MANUFACTURING CONTROL PADA INDUSTRI MEBEL (STUDI KASUS PT “X”

    Directory of Open Access Journals (Sweden)

    Sri Hartini

    2012-02-01

    Full Text Available Load Oriented Manufacturing Control (LOMC is an input-output control system development thatconsidered work load in every work center. Production planning starts with determining production leadtime, then work load control (WLC. WLC consist of defining criteria and determining release procedure tothe shop floor for items that will be processed. This research tried to implement LOMC concept in afurniture company called PT.X. The result of the research showed that LOMC could improve throughputand minimize work in process (WIP.

  10. Active chemistry control for coolant helium applying high-temperature gas-cooled reactors - HTR2008-58096

    International Nuclear Information System (INIS)

    Lifetime extension of high-temperature equipment such as the intermediate heat exchanger of high-temperature gas-cooled reactors (HTGRs) is important from the economical point of view. Since the replacing cost will cause the increasing of the running cost, it is important to reduce replacing times of the high-cost primary equipment during assumed reactor lifetime. In the past, helium chemistry has been controlled by the passive chemistry control technology in which chemical impurity in the coolant helium is removed as low concentration as possible, as does Japan's HTTR. Although the lifetime of high- temperature equipment almost depends upon the chemistry conditions in the coolant helium, it is necessary to establish an active chemistry control technology to maintain adequate chemical conditions. In this study, carbon deposition which could occur at the surface of the heat transfer tubes of the intermediate heat exchanger and decarburization of the high-temperature material of Hastelloy XR used at the heat transfer tubes were evaluated by referring the actual chemistry data obtained by the HTTR. The chemical equilibrium study contributed to clarify the algorism of the chemistry behaviours to be controlled. The created algorism is planned to be added to the instrumentation system of the helium purification systems. In addition, the chemical composition to be maintained during the reactor operation was proposed by evaluating not only core graphite oxidation but also carbon deposition and decarburization. It was identified when the chemical composition could not keep adequately, injection of 10 ppm carbon monoxide could effectively control the chemical composition to the designated stable area where the high-temperature materials could keep their structural integrity beyond the assumed duration. The proposed active chemistry control technology is expected to contribute economically to the purification systems of the future very high-temperature reactors. (authors)

  11. From lab to industrial: PZT nanoparticles synthesis and process control for application in additive manufacturing

    Science.gov (United States)

    Huang, Hsien-Lin

    Lead Zirconate Titanate (PZT) nanoparticles hold many promising current and future applications, such as PZT ink for 3-D printing or seeds for PZT thick films. One common method is hydrothermal growth, in which temperature, duration time, or mineralizer concentrations are optimized to produce PZT nanoparticles with desired morphology, controlled size and size distribution. A modified hydrothermal process is used to fabricate PZT nanoparticles. The novelty is to employ a high ramping rate (e.g., 20 deg C/min) to generate abrupt supersaturation so as to promote burst nucleation of PZT nanoparticles as well as a fast cooling rate (e.g., 5 deg C/min) with a controlled termination of crystal growth. As a result, PZT nanoparticles with a size distribution ranging from 200 nm to 800 nm are obtained with cubic morphology and good crystallinity. The identification of nanoparticles is confirmed through use of X-ray diffractometer (XRD). XRD patterns are used to compare sample variations in their microstructures such as lattice parameter. A cubic morphology and particle size are also examined via SEM images. The hydrothermal process is further modified with excess lead (from 20% wt. to 80% wt.) to significantly reduce amorphous phase and agglomeration of the PZT nanoparticles. With a modified process, the particle size still remains within the 200 nm to 800 nm. Also, the crystal structures (microstructure) of the samples show little variations. Finally, a semi-continuous hydrothermal manufacturing process was developed to substantially reduce the fabrication time and maintained the same high quality as the nanoparticles prepared in an earlier stage. In this semi-continuous process, a furnace is maintained at the process temperature (200 deg C), whereas autoclaves containing PZT sol are placed in and out of the furnace to control the ramp-up and cooling rates. This setup eliminates an extremely time-consuming step of cooling down the furnace, thus saving tremendous amount of

  12. Evaluation of Manufacturability of Embedded Sensors and Controls with Canned Rotor Pump System

    Energy Technology Data Exchange (ETDEWEB)

    Kisner, Roger A [ORNL; Fugate, David L [ORNL; Melin, Alexander M [ORNL; Holcomb, David Eugene [ORNL; Wilson, Dane F [ORNL; Silva, Pamela C [ORNL; Cruz Molina, Carola [ORNL

    2013-07-01

    This report documents the current status of fabrication and assembly planning for the magnetic bearing, canned rotor pump being used as a demonstration platform for deeply integrating I&C into nuclear power plant components. The report identifies material choices and fabrication sequences for all of the required parts and the issues that need to be either resolved or accommodated during the manufacturing process. Down selection between material options has not yet been performed. Potential suppliers for all of the necessary materials have also been identified. The assembly evaluation begins by logically subdividing the pump into modules, which are themselves decomposed into individual parts. Potential materials and fabrication processes for each part in turn are then evaluated. The evaluation process includes assessment of the environmental compatibility requirements and the tolerances available for the selected fabrication processes. A description of the pump power/control electronics is also provided. The report also includes exploded views of the modules that show the integration of the various parts into modules that are then assembled to form the pump. Emphasis has been placed on thermal environment compatibility and the part dimensional changes during heat-up. No insurmountable fabrication or assembly challenges have been identified.

  13. Fuel manufacturing and utilization

    International Nuclear Information System (INIS)

    The efficient utilisation of nuclear fuel requires manufacturing facilities capable of making advanced fuel types, with appropriate quality control. Once made, the use of such fuels requires a proper understanding of their behaviour in the reactor environment, so that safe operation for the design life can be achieved. The International Atomic Energy Agency supports Member States to improve in-pile fuel performance and management of materials; and to develop advanced fuel technologies for ensuring reliability and economic efficiency of the nuclear fuel cycle. It provides assistance to Member States to support fuel-manufacturing capability, including quality assurance techniques, optimization of manufacturing parameters and radiation protection. The IAEA supports the development fuel modelling expertise in Member States, covering both normal operation and postulated and severe accident conditions. It provides information and support for the operation of Nuclear Power Plant to ensure that the environment and water chemistry is appropriate for fuel operation. The IAEA supports fuel failure investigations, including equipment for failed fuel detection and for post-irradiation examination and inspection, as well as fuel repair, it provides information and support research into the basic properties of fuel materials, including UO2, MOX and zirconium alloys. It further offers guidance on the relationship with back-end requirement (interim storage, transport, reprocessing, disposal), fuel utilization and management, MOX fuels, alternative fuels and advanced fuel technology

  14. Data processing technologies and diagnostics for water chemistry and corrosion control in nuclear power plants (DAWAC). Report of a coordinated research project 2001-2005

    International Nuclear Information System (INIS)

    This publication provides information on the current status and development trends in monitoring, diagnostics and control of water chemistry and corrosion of core and primary circuit materials in water cooled power reactors. It summarizes the results of an IAEA Coordinated Research Project and focuses on the methods for development, qualification and implementation of water chemistry expert systems at nuclear power plants. These systems are needed to have full benefit from using on-line sensors in real time mode when sensor signals, and other chemistry and operational data, are collected and continuously analysed with data acquisition and evaluation software. Technical knowledge was acquired in water chemistry control techniques (grab sampling, on-line monitoring, data collecting and processing, etc), plant chemistry and corrosion diagnostics, plant monitoring (corrosion, chemistry, activity) and plant chemistry improvement (analytical models and practices). This publication covers contributions from leading experts in water chemistry/corrosion, representing organizations from 16 countries with the largest nuclear capacities

  15. Improvement of process control using wafer geometry for enhanced manufacturability of advanced semiconductor devices

    Science.gov (United States)

    Lee, Honggoo; Lee, Jongsu; Kim, Sang Min; Lee, Changhwan; Han, Sangjun; Kim, Myoungsoo; Kwon, Wontaik; Park, Sung-Ki; Vukkadala, Pradeep; Awasthi, Amartya; Kim, J. H.; Veeraraghavan, Sathish; Choi, DongSub; Huang, Kevin; Dighe, Prasanna; Lee, Cheouljung; Byeon, Jungho; Dey, Soham; Sinha, Jaydeep

    2015-03-01

    Aggressive advancements in semiconductor technology have resulted in integrated chip (IC) manufacturing capability at sub-20nm half-pitch nodes. With this, lithography overlay error budgets are becoming increasingly stringent. The delay in EUV lithography readiness for high volume manufacturing (HVM) and the need for multiple-patterning lithography with 193i technology has further amplified the overlay issue. Thus there exists a need for technologies that can improve overlay errors in HVM. The traditional method for reducing overlay errors predominantly focused on improving lithography scanner printability performance. However, processes outside of the lithography sector known as processinduced overlay errors can contribute significantly to the total overlay at the current requirements. Monitoring and characterizing process-induced overlay has become critical for advanced node patterning. Recently a relatively new technique for overlay control that uses high-resolution wafer geometry measurements has gained significance. In this work we present the implementation of this technique in an IC fabrication environment to monitor wafer geometry changes induced across several points in the process flow, of multiple product layers with critical overlay performance requirement. Several production wafer lots were measured and analyzed on a patterned wafer geometry tool. Changes induced in wafer geometry as a result of wafer processing were related to down-stream overlay error contribution using the analytical in-plane distortion (IPD) calculation model. Through this segmentation, process steps that are major contributors to down-stream overlay were identified. Subsequent process optimization was then isolated to those process steps where maximum benefit might be realized. Root-cause for the within-wafer, wafer-to-wafer, tool-to-tool, and station-to-station variations observed were further investigated using local shape curvature changes - which is directly related to

  16. Applications of dimensional micro metrology to the product and process quality control in manufacturing of precision polymer micro components

    DEFF Research Database (Denmark)

    Tosello, Guido; Hansen, Hans Nørgaard; Gasparin, Stefania

    2009-01-01

    IM components selected from industrial production. Two systems were analysed: a tactile coordinate measuring machine (CMM) with sub-micrometer uncertainty and an optical CMM allowing fast measurements suitable for in-line quality control. Product quality control capability, measuring uncertainty and...... calibration guidelines are discussed for both systems. Finally, a new approach for the manufacturing of hybrid micro polymer-metal calibrated objects is proposed....

  17. Control of Discrete Event Systems by Means of Discrete Optimization and Disjunctive Colored PNs: Application to Manufacturing Facilities

    OpenAIRE

    Juan-Ignacio Latorre-Biel; Emilio Jiménez-Macías; Mercedes Pérez de la Parte; Julio Blanco-Fernández; Eduardo Martínez-Cámara

    2014-01-01

    Artificial intelligence methodologies, as the core of discrete control and decision support systems, have been extensively applied in the industrial production sector. The resulting tools produce excellent results in certain cases; however, the NP-hard nature of many discrete control or decision making problems in the manufacturing area may require unaffordable computational resources, constrained by the limited available time required to obtain a solution. With the purpose of improving the e...

  18. Self-organization principles result in robust control of flexible manufacturing systems

    DEFF Research Database (Denmark)

    problems with several autonomous robots and several targets are considered as model of flexible manufacturing systems. Each manufacturing target has to be served in a given time interval by one and only one robot and the total working costs have to be minimized (or total winnings maximized). A specifically...... adapting pattern formation principles to these problems either no feasibility is guaranteed or only unrealistic toy problems like one-step problems, i.e. no sequences of tasks, are treated. These limitations are overcome in the present work where sequential manufacturing tasks in logical order are fully...

  19. Polydopamine film coated controlled-release multielement compound fertilizer based on mussel-inspired chemistry.

    Science.gov (United States)

    Jia, Xin; Ma, Zhi-yuan; Zhang, Guo-xiang; Hu, Jia-mei; Liu, Zhi-yong; Wang, He-yun; Zhou, Feng

    2013-03-27

    This work reports on a facile and reliable method to prepare a polydopamine film coated controlled-release multielement compound fertilizer (PCMCF) based on mussel-inspired chemistry for the first time. The polydopamine (Pdop) film was coated on double copper potassium pyrophosphate trihydrate, providing three essential nutrients (Cu, K, and P) by spontaneous oxidative polymerization of dopamine. The thickness of the polymer coating of the fertilizer was controlled by using the multistep deposition technique. The morphology and composition of the products were characterized by transmission electron microscopy, inductively coupled plasma emission spectrometer, a vis spectrophotometer, and a Kjeltec autoanalyzer. The controlled-release behavior of four elements, including nitrogen from Pdop, was evaluated in water and in soil (sterilized or not). The results revealed that the coated fertilizers had good slow-release properties, incubated in either water or soil. It is noted that the release rate of nutrients of PCMCF can be tailored by the thickness of the Pdop coating, and the Pdop coating can be biodegraded in soil. This coating technology will be effective and promising in the research and development of controlled-release fertilizer. PMID:23464683

  20. Spatially Controlled Delivery of siRNAs to Stem Cells in Implants Generated by Multi-Component Additive Manufacturing

    DEFF Research Database (Denmark)

    Andersen, Morten Østergaard; Le, Dang Quang Svend; Chen, Muwan;

    2013-01-01

    Additive manufacturing is a promising technique in tissue engineering, as it enables truly individualized implants to be made to fit a particular defect. As previously shown, a feasible strategy to produce complex multicellular tissues is to deposit different small interfering RNA (siRNA) in porous...... implants that are subsequently sutured together. In this study, an additive manufacturing strategy to deposit carbohydrate hydrogels containing different siRNAs is applied into an implant, in a spatially controlled manner. When the obtained structures are seeded with mesenchymal stem (stromal) cells, the...... selected siRNAs are delivered to the cells and induces specific and localized gene silencing. Here, it is demonstrated how to replicate part of a patient's spinal cord from a computed tomography scan, using an additive manufacturing technique to produce an implant with compartmentalized siRNAs in the...

  1. Alloy chemistry and microstructural control to meet the demands of the automotive Stirling engine

    Science.gov (United States)

    Stephens, J. R.

    1986-01-01

    The automotive Stirling engine now under development by DOE/NASA as an alternative to the internal combustion engine, imposes severe materials requirements for the hot portion of the engine. Materials selected must be low cost and contain a minimum of strategic elements so that availability is not a problem. Heater head tubes contain high pressure hydrogen on the inside and are exposed to hot combustion gases on the outside surface. The cylinders and regenerator housings must be readily castable into complex shapes having varying wall thicknesses and be amenable to brazing and welding operations. Also, high strength, oxidation resistance, resistance to hydrogen permeation, cyclic operation, and long-life are required. A research program conducted by NASA Lewis focused on alloy chemistry and microstructural control to achieve the desired properties over the life of the engine. Results of alloy selection, characterization, evaluation, and actual engine testing of selected materials are presented.

  2. Introducing Quality Control in the Chemistry Teaching Laboratory Using Control Charts

    Science.gov (United States)

    Schazmann, Benjamin; Regan, Fiona; Ross, Mary; Diamond, Dermot; Paull, Brett

    2009-01-01

    Quality control (QC) measures are less prevalent in teaching laboratories than commercial settings possibly owing to a lack of commercial incentives or teaching resources. This article focuses on the use of QC assessment in the analytical techniques of high performance liquid chromatography (HPLC) and ultraviolet-visible spectroscopy (UV-vis) at…

  3. CONTROL TECHNOLOGY OVERVIEW REPORT: CFC-11 EMISSIONS FROM FLEXIBLE POLYURETHANE FOAM MANUFACTURING

    Science.gov (United States)

    The report gives results of an engineering evaluation of technical options to reduce chlorofluorocarbon (CFC) emissions from flexible slabstock and molded polyurethane foam manufacturing plants. Among the technical options studied were recovery and recycle of CFC-11, alternative ...

  4. 77 FR 55504 - Manufacturer of Controlled Substances; Notice of Registration; Research Triangle Institute

    Science.gov (United States)

    2012-09-10

    ... Institute By Notice dated May 15, 2012, and published in the Federal Register on May 22, 2012, 77 FR 30327... Marihuana (7360) I Cocaine (9041) II The Institute will manufacture marihuana, and cocaine derivatives...

  5. Green Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Patten, John

    2013-12-31

    Green Manufacturing Initiative (GMI): The initiative provides a conduit between the university and industry to facilitate cooperative research programs of mutual interest to support green (sustainable) goals and efforts. In addition to the operational savings that greener practices can bring, emerging market demands and governmental regulations are making the move to sustainable manufacturing a necessity for success. The funding supports collaborative activities among universities such as the University of Michigan, Michigan State University and Purdue University and among 40 companies to enhance economic and workforce development and provide the potential of technology transfer. WMU participants in the GMI activities included 20 faculty, over 25 students and many staff from across the College of Engineering and Applied Sciences; the College of Arts and Sciences' departments of Chemistry, Physics, Biology and Geology; the College of Business; the Environmental Research Institute; and the Environmental Studies Program. Many outside organizations also contribute to the GMI's success, including Southwest Michigan First; The Right Place of Grand Rapids, MI; Michigan Department of Environmental Quality; the Michigan Department of Energy, Labor and Economic Growth; and the Michigan Manufacturers Technical Center.

  6. Strategic elements of steam cycle chemistry control practices at TXU's Comanche Peak steam electric station

    International Nuclear Information System (INIS)

    Early industry experience defined the critical importance of Chemistry Control Practices to maintaining long-term performance of PWR steam generators. These lessons provided the impetus for a number of innovations and alternate practices at Comanche Peak. For example, advanced amine investigations and implementation of results provided record low iron transport and deposition. The benefits of the surface-active properties of dimethyl-amine exceeded initial expectations. Operation of pre-coat polishers and steam generator blowdown demineralizers in the amine cycle enabled optimization of amine concentrations and stable pH control. The strategy for coordinated control of oxygen and hydrazine dosing complemented the advanced amine program for protective oxide stabilization. Additionally, a proactive chemical cleaning was performed on Unit 1 to prevent degradations from general fouling of steam generator tube-tube support plate (TSP) and top-of-tubesheet (TTS) crevices. This paper shares the results of these innovations and practices. Also, the bases, theory, and philosophy supporting the strategic elements of program will be presented. (authors)

  7. DIMENSIONAL VERIFICATION AND QUALITY CONTROL OF IMPLANTS PRODUCED BY ADDITIVE MANUFACTURING

    Directory of Open Access Journals (Sweden)

    Teodor Toth

    2015-07-01

    Full Text Available Purpose: Development of computer technology and alternative manufacturing methods in form of additive manufacturing leads to the manufacture of products with complex shapes. In the field of medicine they include, inter alia, custom-made implants manufactured for a particular patient, such as cranial implants, maxillofacial implants, etc. With regard to the fact that such implants are inserted into a patient’s body, it is necessary to perform the verification, including the shape and dimensional verification. The article deals with the application of the industrial computer tomography within the process of inspection and verification of selected custom-made implant types.Methodology/Approach: The Department of Biomedical Engineering and Measurement performs the verification of medicinal products manufactured by the additive manufacturing technologies from the Ti-6Al-4V (Grade 5 titanium alloy, using the coordinate measuring machine Carl Zeiss Contura G2 and the industrial computed tomography machine Carl Zeiss Metrotom 1500. These equipment fulfil the requirements for the identification and evaluation of dimensions of both, the external and the internal structures. Findings: The article presents the possibilities of the computed tomography utilisation in the inspection of individual implant manufacture using the additive manufacturing technologies. The results indicate that with the adjustment of appropriate input parameters (alignment, this technology is appropriate for the analysis of shape deviations, when compared with the CAD model.Research Limitation/implication: With the increasing distance of measured object from X-ray source, the machine’s resolution function decreases. Decreasing of resolution has a minor impact on the measured dimensions (relatively high tolerances, but has a significant impact on the evaluation of porosity and inclusions. Originality/Value of paper: Currently, the verification of a manufactured implant  can be

  8. Hydrogeochemical processes controlling water and dissolved gas chemistry at the Accesa sinkhole (southern Tuscany, central Italy

    Directory of Open Access Journals (Sweden)

    Franco Tassi

    2014-05-01

    Full Text Available The 38.5 m deep Lake Accesa is a sinkhole located in southern Tuscany (Italy that shows a peculiar water composition, being characterized by relatively high total dissolved solids (TDS values (2 g L-1 and a Ca(Mg-SO4 geochemical facies. The presence of significant amounts of extra-atmospheric gases (CO2 and CH4, which increase their concentrations with depth, is also recognized. These chemical features, mimicking those commonly shown by volcanic lakes fed by hydrothermal-magmatic reservoirs, are consistent with those of mineral springs emerging in the study area whose chemistry is produced by the interaction of meteoric-derived waters with Mesozoic carbonates and Triassic evaporites. Although the lake has a pronounced thermocline, water chemistry does not show significant changes along the vertical profile. Lake water balance calculations demonstrate that Lake Accesa has >90% of its water supply from sublacustrine springs whose subterranean pathways are controlled by the local structural assessment that likely determined the sinking event, the resulting funnel-shape being then filled by the Accesa waters. Such a huge water inflow from the lake bottom (~9·106 m3 yr-1 feeds the lake effluent (Bruna River and promotes the formation of water currents, which are able to prevent the establishment of a vertical density gradient. Consequently, a continuous mixing along the whole vertical water column is established. Changes of the drainage system by the deep-originated waters in the nearby former mining district have strongly affected the outflow rates of the local mineral springs; thus, future intervention associated with the ongoing remediation activities should carefully be evaluated to preserve the peculiar chemical features of Lake Accesa.

  9. Sigma metrics in clinical chemistry laboratory – A guide to quality control

    Directory of Open Access Journals (Sweden)

    Usha S. Adiga

    2015-10-01

    Full Text Available Background: Six sigma is a process of quality measurement and improvement program used in industries. Sigma methodology can be applied wherever an outcome of a process is to be measured. A poor outcome is counted as an error or defect. This is quantified as defects per million (DPM. Six sigma provides a more quantitative frame work for evaluating process performance with evidence for process improvement and describes how many sigma fit within the tolerance limits. Sigma metrics can be used effectively in laboratory services. The present study was undertaken to evaluate the quality of the analytical performance of clinical chemistry laboratory by calculating sigma metrics. Methodology: The study was conducted in the clinical biochemistry laboratory of Karwar Institute of Medical Sciences, Karwar. Sigma metrics of 15 parameters with automated chemistry analyzer, transasia XL 640 were analyzed. The analytes assessed were glucose, urea, creatinine, uric acid, total bilirubin (BT, direct bilirubin (BD, total protein, albumin, SGOT, SGPT, ALP, Total cholesterol, triglycerides, HDL and Calcium. Results: We have sigma values <3 for Urea, ALT, BD, BT, Ca, creatinine (L1 and urea, AST, BD (L2. Sigma lies between 3-6 for Glucose, AST, cholesterol, uric acid, total protein(L1 and ALT, cholesterol, BT, calcium, creatinine and glucose (L2.Sigma was more than 6 for Triglyceride, ALP, HDL, albumin (L1 and TG, uric acid, ALP, HDL, albumin, total protein(L2. Conclusion: Sigma metrics helps to assess analytical methodologies and augment laboratory performance. It acts as a guide for planning quality control strategy. It can be a self assessment tool regarding the functioning of clinical laboratory.

  10. Relational-database model for improving quality assurance and process control in a composite manufacturing environment

    Science.gov (United States)

    Gentry, Jeffery D.

    2000-05-01

    A relational database is a powerful tool for collecting and analyzing the vast amounts of inner-related data associated with the manufacture of composite materials. A relational database contains many individual database tables that store data that are related in some fashion. Manufacturing process variables as well as quality assurance measurements can be collected and stored in database tables indexed according to lot numbers, part type or individual serial numbers. Relationships between manufacturing process and product quality can then be correlated over a wide range of product types and process variations. This paper presents details on how relational databases are used to collect, store, and analyze process variables and quality assurance data associated with the manufacture of advanced composite materials. Important considerations are covered including how the various types of data are organized and how relationships between the data are defined. Employing relational database techniques to establish correlative relationships between process variables and quality assurance measurements is then explored. Finally, the benefits of database techniques such as data warehousing, data mining and web based client/server architectures are discussed in the context of composite material manufacturing.

  11. Biodegradable hyaluronic acid hydrogels to control release of dexamethasone through aqueous Diels–Alder chemistry for adipose tissue engineering

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Ming; Ma, Ye; Zhang, Ziwei; Mao, Jiahui [School of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing (China); Tan, Huaping, E-mail: hptan@njust.edu.cn [School of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing (China); Hu, Xiaohong [School of Material Engineering, Jinling Institute of Technology, Nanjing (China)

    2015-11-01

    A robust synthetic strategy of biopolymer-based hydrogels has been developed where hyaluronic acid derivatives reacted through aqueous Diels–Alder chemistry without the involvement of chemical catalysts, allowing for control and sustain release of dexamethasone. To conjugate the hydrogel, furan and maleimide functionalized hyaluronic acid were synthesized, respectively, as well as furan functionalized dexamethasone, for the covalent immobilization. Chemical structure, gelation time, morphologies, swelling kinetics, weight loss, compressive modulus and dexamethasone release of the hydrogel system in PBS at 37 °C were studied. The results demonstrated that the aqueous Diels–Alder chemistry provides an extremely selective reaction and proceeds with high efficiency for hydrogel conjugation and covalent immobilization of dexamethasone. Cell culture results showed that the dexamethasone immobilized hydrogel was noncytotoxic and preserved proliferation of entrapped human adipose-derived stem cells. This synthetic approach uniquely allows for the direct fabrication of biologically functionalized gel scaffolds with ideal structures for adipose tissue engineering, which provides a competitive alternative to conventional conjugation techniques such as copper mediated click chemistry. - Highlights: • A biodegradable hyaluronic acid hydrogel was crosslinked via aqueous Diels–Alder chemistry. • Dexamethasone was covalently immobilized into the hyaluronic acid hydrogel via aqueous Diels–Alder chemistry. • Dexamethasone could be released from the Diels–Alder hyaluronic acid hydrogel in a controlled fashion.

  12. Biodegradable hyaluronic acid hydrogels to control release of dexamethasone through aqueous Diels–Alder chemistry for adipose tissue engineering

    International Nuclear Information System (INIS)

    A robust synthetic strategy of biopolymer-based hydrogels has been developed where hyaluronic acid derivatives reacted through aqueous Diels–Alder chemistry without the involvement of chemical catalysts, allowing for control and sustain release of dexamethasone. To conjugate the hydrogel, furan and maleimide functionalized hyaluronic acid were synthesized, respectively, as well as furan functionalized dexamethasone, for the covalent immobilization. Chemical structure, gelation time, morphologies, swelling kinetics, weight loss, compressive modulus and dexamethasone release of the hydrogel system in PBS at 37 °C were studied. The results demonstrated that the aqueous Diels–Alder chemistry provides an extremely selective reaction and proceeds with high efficiency for hydrogel conjugation and covalent immobilization of dexamethasone. Cell culture results showed that the dexamethasone immobilized hydrogel was noncytotoxic and preserved proliferation of entrapped human adipose-derived stem cells. This synthetic approach uniquely allows for the direct fabrication of biologically functionalized gel scaffolds with ideal structures for adipose tissue engineering, which provides a competitive alternative to conventional conjugation techniques such as copper mediated click chemistry. - Highlights: • A biodegradable hyaluronic acid hydrogel was crosslinked via aqueous Diels–Alder chemistry. • Dexamethasone was covalently immobilized into the hyaluronic acid hydrogel via aqueous Diels–Alder chemistry. • Dexamethasone could be released from the Diels–Alder hyaluronic acid hydrogel in a controlled fashion

  13. Impact of the Flipped Classroom on Student Performance and Retention: A Parallel Controlled Study in General Chemistry

    Science.gov (United States)

    Ryan, Michael D.; Reid, Scott A.

    2016-01-01

    Despite much recent interest in the flipped classroom, quantitative studies are slowly emerging, particularly in the sciences. We report a year-long parallel controlled study of the flipped classroom in a second-term general chemistry course. The flipped course was piloted in the off-semester course in Fall 2014, and the availability of the…

  14. Development and control of the process for the manufacture of zircaloy-4 tubing for LWBR fuel rods

    Energy Technology Data Exchange (ETDEWEB)

    Eyler, J.H.

    1981-01-01

    The technical requirements for the Light Water Breeder Reactor (LWBR) fuel elements (fuel rods) imposed certain unique requirements for the low hafnium Zircaloy-4 tubing used as fuel rod cladding. This report describes, in detail, the tube manufacturing process, the product and process controls used, the inspections and tests performed, and the efforts involved in refining a commercial tube reducing process to produce tubes that would satisfy the requirements for LWBR fuel rod cladding.

  15. Development and control of the process for the manufacture of zircaloy-4 tubing for LWBR fuel rods

    International Nuclear Information System (INIS)

    The technical requirements for the Light Water Breeder Reactor (LWBR) fuel elements (fuel rods) imposed certain unique requirements for the low hafnium Zircaloy-4 tubing used as fuel rod cladding. This report describes, in detail, the tube manufacturing process, the product and process controls used, the inspections and tests performed, and the efforts involved in refining a commercial tube reducing process to produce tubes that would satisfy the requirements for LWBR fuel rod cladding

  16. Current good manufacturing practices, quality control procedures, quality factors, notification requirements, and records and reports, for infant formula. Final rule.

    Science.gov (United States)

    2014-06-10

    The Food and Drug Administration (FDA or we) is issuing a final rule that adopts, with some modifications, the interim final rule (IFR) entitled "Current Good Manufacturing Practices, Quality Control Procedures, Quality Factors, Notification Requirements, and Records and Reports, for Infant Formula'' (February 10, 2014). This final rule affirms the IFR's changes to FDA's regulations and provides additional modifications and clarifications. The final rule also responds to certain comments submitted in response to the request for comments in the IFR. PMID:24922980

  17. Costing support and cost control in manufacturing. A cost estimation tool applied in the sheet metal domain.

    OpenAIRE

    Brinke, ten, G

    2002-01-01

    In the product development cycle several engineering tasks like design, process planning and production planning have to be executed. The execution of these tasks mainly involves information processing and decision-making. Because costs is an important factor in manufacturing, adequate information about costs is extremely valuable for all engineering tasks. Therefore, a cost estimation system for the generation of cost information and for cost control, integrated in the product development cy...

  18. Start-up conditions and the performance of women – and men- controlled businesses in manufacturating industries

    OpenAIRE

    Prior Jiménez, Diego; Driga, Otilia

    2009-01-01

    Recent research on the economic performance of women-controlled firms suggests that their underperformance may not result from differences in the managerial ability of women as compared to men, but it can be the result of different levels of start-up resources. Using accounting data, this paper examines the effects that selected start-up conditions have on the economic performance observed in a sample of 4450 Spanish manufacturing firms. The results indicate significant differences regarding ...

  19. Chemistry and radiochemistry strategies supported by FA3-EPRTM and UK-EPRTM auxiliary systems: performances and control

    International Nuclear Information System (INIS)

    The design and the operation of auxiliary systems play an essential role in: - the preservation of the primary circuit integrity, - the prevention of hydrogen risk, - the control of the boron concentration and radioactivity, - the application of pH and zinc programmes. While the source term generation mainly depends on the primary circuit material and primary coolant chemistry conditioning, the source term spreading is directly linked to the auxiliary systems treatment and performances. Indeed, the auxiliary systems regulate the boron, hydrogen, lithium and zinc injection as well as the countermeasures to ensure the reactivity control and the hazardous H2/O2 mixture prevention. The main principles governing the chemistry and radiochemistry in the auxiliary systems are based on the application of: - Design features for hydrogen and boron management. - Criteria for selecting the appropriate material of each system considering the functional requirements and the source term build up reduction. - Measures for minimizing the activity deposition on the surfaces of components and pipings. - Adequate and reliable systems of purification for reducing the accumulation of liquid/gas radioactivity and impurities in the circuits and for optimizing the waste production. - Chemistry program for limiting the material corrosion of auxiliary systems and preventing the source term transfer to the core. - Appropriate sampling locations and equipment to monitor the chemistry and radiochemistry parameters. This paper describes the operation of the main auxiliary systems of FLAMANVILLE3-EPRTM and UK-EPR-TM participating in the chemistry/radiochemistry management such as Chemical and Volume Control System (CVCS), Reactor Borated Water Make-up System (RBWMS), Coolant Treatment System (CTS), Gaseous Waste Processing System (GWPS), Fuel Pool Purification System (PTR [FPPS/FPCS]) also. The performances requested to these systems and the chemistry programs applied to them are discussed

  20. 77 FR 30028 - Manufacturer of Controlled Substances; Notice of Registration; Johnson Matthey, Inc...

    Science.gov (United States)

    2012-05-21

    ...., Pharmaceuticals Materials By Notice dated January 6, 2012, and published in the Federal Register on January 17, 2012, 77 FR 2324, Johnson Matthey, Inc., Pharmaceuticals Materials, 900 River Road, Conshohocken... determined that the registration of Johnson Matthey Inc., Pharmaceuticals Materials to manufacture the...

  1. 78 FR 15975 - Manufacturer of Controlled Substances, Notice of Registration; Johnson Matthey, Inc...

    Science.gov (United States)

    2013-03-13

    ...., Pharmaceuticals Materials By Notice dated November 1, 2012, and published in the Federal Register on November 9, 2012, 77 FR 67397, Johnson Matthey, Inc., Pharmaceuticals Materials, 900 River Road, Conshohocken... registration of Johnson Matthey Inc., Pharmaceuticals Materials to manufacture the listed basic classes...

  2. 78 FR 39340 - Manufacturer of Controlled Substances; Notice of Registration; Patheon Pharmaceuticals, Inc.

    Science.gov (United States)

    2013-07-01

    ... Pharmaceuticals, Inc. By Notice dated March 20, 2013, and published in the Federal Register on March 28, 2013, 78 FR 19016, Patheon ] Pharmaceutical, Inc., 2110 E. Galbraith Road, Cincinnati, Ohio 45237, made...) and determined that the registration of Patheon Pharmaceuticals, Inc., to manufacture the listed...

  3. 78 FR 52802 - Manufacturer of Controlled Substances; Notice of Registration; Morton Grove Pharmaceuticals

    Science.gov (United States)

    2013-08-26

    ... Pharmaceuticals By Notice dated March 12, 2013, and published in the Federal Register on March 20, 2013, 78 FR 17231, Morton Grove Pharmaceuticals, 6451 Main Street, Morton Grove, Illinois 60053-2633, made... determined that the registration of Morton Grove Pharmaceuticals to manufacture the listed basic class...

  4. 78 FR 5503 - Manufacturer of Controlled Substances, Notice of Registration; Morton Grove Pharmaceuticals

    Science.gov (United States)

    2013-01-25

    ... Pharmaceuticals By Notice dated September 25, 2012, and published in the Federal Register on October 2, 2012, 77 FR 60144, Morton Grove Pharmaceuticals, 6451 Main Street, Morton Grove, Illinois 60053-2633, made... determined that the registration of Morton Grove Pharmaceuticals to manufacture the listed basic class...

  5. 77 FR 70189 - Manufacturer of Controlled Substances; Notice of Registration; Cayman Chemical Company

    Science.gov (United States)

    2012-11-23

    ... Company By Notice dated July 30, 2012, and published in the Federal Register on August 7, 2012, 77 FR... diethylamide (7315) I 2,5-Dimethoxy-4-(n)- I propylthiophenethylamine (7348). Marihuana (7360) I... (1105) II Lisdexamfetamine (1205) II The company plans to manufacture small quantities of...

  6. 77 FR 47115 - Manufacturer of Controlled Substances; Notice of Application; Cayman Chemical Company

    Science.gov (United States)

    2012-08-07

    ... diethylamide (7315) I 2,5-Dimethoxy-4-(n)-propylthiophenethylamine I (7348). Marihuana (7360) I... small quantities of marihuana derivatives for research purposes. In reference to drug code 7360 (Marihuana), the company plans to bulk manufacture cannabidiol. In reference to drug code...

  7. Investigating Affective Experiences in the Undergraduate Chemistry Laboratory: Students' Perceptions of Control and Responsibility

    Science.gov (United States)

    Galloway, Kelli R.; Malakpa, Zoebedeh; Bretz, Stacey Lowery

    2016-01-01

    Meaningful learning requires the integration of cognitive and affective learning with the psychomotor, i.e., hands-on learning. The undergraduate chemistry laboratory is an ideal place for meaningful learning to occur. However, accurately characterizing students' affective experiences in the chemistry laboratory can be a very difficult task. While…

  8. Water chemistry and corrosion control of cladding and primary circuit components. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    Corrosion is the principal life limiting degradation mechanism in nuclear steam supply systems, especially taking into account the trends to increase fuel burnup, thermal rate and cycle length. Primary circuit components of water cooled power reactors have an impact on Zr-based alloys behaviour due to crud (primary circuit corrosion products) formation, transport and deposition on heat transfer surfaces. Crud deposits influence water chemistry, radiation and thermal hydraulic conditions near cladding surface, and by this way-Zr-based alloy corrosion. During the last decade, significant improvements were achieved in the reduction of the corrosion and dose rates by changing the cladding material for one more resistant to corrosion or by the improvement of water chemistry conditions. However, taking into account the above mentioned tendency for heavier fuel duties, corrosion and water chemistry, control will remain a serious task to work with for nuclear power plant operators and scientists, as well as development of generally accepted corrosion model of Zr-based alloys in a water environment in a new millennium. Upon the recommendation of the International Working Group on Water Reactor Fuel Performance and Technology, water chemistry and corrosion of cladding and primary circuit components are in the focus of the IAEA activities in the area of fuel technology and performance. At present the IAEA performs two co-ordinated research projects (CRPs): on On-line High Temperature Monitoring of Water Chemistry and Corrosion (WACOL) and on Activity Transport in Primary Circuits. Two CRPs deal with hydrogen and hydride degradation of the Zr-based alloys. A state-of-the-art review entitled: 'Waterside Corrosion of Zirconium Alloys in Nuclear Power Plants' was published in 1998. Technical Committee meetings on the subject were held in 1985 (Cadarache, France), 1989 (Portland, USA), 1993 (Rez, Czech Republic). During the last few years extensive exchange of experience in

  9. Data fusion for adaptive control in manufacturing: Impact on engineering information models

    Energy Technology Data Exchange (ETDEWEB)

    Bray, O.H.

    1997-01-01

    Data fusion is the integration and analysis of data from multiple sensors to develop a more accurate understanding of a situation and determine how to respond to it. Although data fusion can be applied in many situations, this paper focuses on its application to manufacturing and how it changes some of the more traditional, less adaptive information models that support the design and manufacturing functions. The paper consists of four parts: Section 1 defines data fusion and explains its impact on manufacturing. Section 2 describes an information system architecture and explains the natural language-based information modeling methodology used by this research project. Section 3 identifies the major design and manufacturing functions, reviews the information models required to support them, and then shows how these models must be extended to support data fusion. Section 4 discusses the future directions of this work. This report is one of three produced by an FY93 LDRD project, Information Integration for Data Fusion. The project confirmed: (1) that the natural language-based information modeling methodology could be used effectively in data fusion areas, and (2) that commonalities could be found that would allow synergy across various data fusion areas, such as defense, manufacturing, and health care. The project found five common objects that are the basis for all of the data fusion areas examined: targets, behaviors, environments, signatures, and sensors. Many of these objects and the specific facts related to them were common across several models and could easily be reused. In some cases, even the terminology remained the same. This commonality is important with the growing use of multisensor data fusion. Data fusion is much more difficult if each type of sensor uses its own objects and models rather than building on a common set. Information model integration at the conceptual level is much easier than at the implementation level.

  10. Building the Interest of High School Students for Science--A PACT Ambassador Program to Investigate Soap Manufacturing and Industrial Chemistry.

    Science.gov (United States)

    Lynch, Matthew; Geary, Nicholas; Hagaman, Karen; Munson, Anne; Sabo, Mark

    1999-01-01

    Describes a program for bringing industrial applications of technology into high schools to enhance students' perceptions of the chemical industry and industrial careers in chemistry. Ambassadors from the Proctor and Gamble Company and Miami University--Middletown helped students work through a typical product-development cycle for fabricating…

  11. News: Good chemical manufacturing process criteria

    Science.gov (United States)

    This news column covers topics relating to manufacturing criteria, machine to machine technology, novel process windows, green chemistry indices, business resilience, immobilized enzymes, and Bt crops.

  12. The "Parade Blue": effects of short-term emission control on aerosol chemistry.

    Science.gov (United States)

    Li, Haiyan; Zhang, Qiang; Duan, Fengkui; Zheng, Bo; He, Kebin

    2016-07-18

    The strict control on emissions implemented in Beijing, China, during the 2015 China Victory Day Parade (V-day Parade) to commemorate the 70(th) Anniversary of Victory in World War II, provided a good opportunity to investigate the relationship between emission sources and aerosol chemistry in a heavily polluted megacity. From August 11 to September 3, 2015, an Aerosol Chemical Speciation Monitor was deployed in urban Beijing, together with other collocated instruments, for the real-time measurement of submicron aerosol characteristics. The average PM1 mass concentration was 11.3 (±6.7) μg m(-3) during the V-day Parade, 63.5% lower than that before the V-day Parade. Differently to the relatively smaller decrease of organics (53%), secondary inorganic aerosols (sulfate, nitrate and ammonium) showed significant reductions of 65-78% during the V-day Parade. According to the positive matrix factorization results, primary organic aerosol (POA) from traffic and cooking emissions decreased by 41.5% during the parade, whereas secondary organic aerosol (SOA) presented a much greater reduction (59%). The net effectiveness of emission control measures was investigated further under comparable weather conditions before and during the parade. By excluding the effects of meteorological parameters, the total PM1 mass was reduced by 52-57% because of the emission controls. Although the mass concentrations of aerosol species were reduced substantially, the PM1 bulk composition was similar before and during the control period as a consequence of synergetic control of various precursors. The emission restrictions also suppressed the secondary formation processes of sulfate and nitrate, indicated by the substantially reduced SOR and NOR (molar ratios of sulfate or nitrate to the sums of the sulfate and SO2 or nitrate and NO2) during the event. The study also explored the influence of emission controls on the evolution of organic aerosol using the mass ratios of SOA/POA and oxygen

  13. Surface trimming of silicon photonics devices using controlled reactive ion etching chemistry

    Science.gov (United States)

    Chandran, S.; Das, B. K.

    2015-06-01

    Surface trimming of rib waveguides fabricated in 5-μm SOI substrate has been carried out successfully without any significant increase of propagation losses. A reactive ion etching chemistry has been optimized for trimming and an empirical model has been developed to obtain the resulting waveguide geometries. This technique has been used to demonstrate smaller footprint devices like multimode interference based power splitters and ring resonators after defining them photolithographically with relatively large cross-section rib waveguides. We have been also successful to fabricate 2D tapered spot-size converter useful for monolithic integration of waveguides with varying heights and widths. The taper length is again precisely controlled by photolithographic definition. Minimum insertion loss of such a spot-size converter integrated between waveguides with 3-μm height difference has been recorded to be ∼2 dB. It has been also shown that the overall fiber-to-chip coupling loss can be reduced by >3 dB by using such spot-size converters at the input/output side of the waveguides.

  14. Controlling orbital-selective Kondo effects in a single molecule through coordination chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Tsukahara, Noriyuki; Kawai, Maki; Takagi, Noriaki, E-mail: n-takagi@k.u-tokyo.ac.jp [Department of Advanced Materials Science, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561 (Japan); Minamitani, Emi; Kim, Yousoo [RIKEN, 2-1 Hirosawa, Saitama 351-0198 (Japan)

    2014-08-07

    Iron(II) phthalocyanine (FePc) molecule causes novel Kondo effects derived from the unique electronic structure of multi-spins and multi-orbitals when attached to Au(111). Two unpaired electrons in the d{sub z}{sup 2} and the degenerate dπ orbitals are screened stepwise, resulting in spin and spin+orbital Kondo effects, respectively. We investigated the impact on the Kondo effects of the coordination of CO and NO molecules to the Fe{sup 2+} ion as chemical stimuli by using scanning tunneling microscopy (STM) and density functional theory calculations. The impacts of the two diatomic molecules are different from each other as a result of the different electronic configurations. The coordination of CO converts the spin state from triplet to singlet, and then the Kondo effects completely disappear. In contrast, an unpaired electron survives in the molecular orbital composed of Fe d{sub z}{sup 2} and NO 5σ and 2π* orbitals for the coordination of NO, causing a sharp Kondo resonance. The isotropic magnetic response of the peak indicates the origin is the spin Kondo effect. The diatomic molecules attached to the Fe{sup 2+} ion were easily detached by applying a pulsed voltage at the STM junction. These results demonstrate that the single molecule chemistry enables us to switch and control the spin and the many-body quantum states reversibly.

  15. A study on manufacturing and quality control technology of DUPIC fuel

    International Nuclear Information System (INIS)

    A series of experiments are performed to verify the manufacturability of DUPIC fuel and its performance by use of HANARO test reactor. Major works performed during this research period are : analysis of manufacturing process of DUPIC fuel, fabrication technology development such as development of disassembly and decladding method of spent PWR fuel, study on the OREOX process using simulated high burnup fuel, weldability of end cap weld, and development of fabrication equipment including the conceptual and detailed design of DUPIC equipment mainly for the powder preparation, pelletization and fuel element fabrication. A study on the material properties of DUPIC fuel and performance analysis method using irradiation of test fuel was also performed. (author). 91 refs., 274 tabs., 254 figs

  16. Advances in clinical NK cell studies: Donor selection, manufacturing and quality control

    OpenAIRE

    Koehl, U; Kalberer, C.; Spanholtz, J.; Lee, D.A.; Miller, J. S.; Cooley, S.; Lowdell, M.; Uharek, L.; Klingemann, H.; Curti, A.; Leung, W; Alici, E.

    2015-01-01

    ABSTRACT Natural killer (NK) cells are increasingly used in clinical studies in order to treat patients with various malignancies. The following review summarizes platform lectures and 2013–2015 consortium meetings on manufacturing and clinical use of NK cells in Europe and United States. A broad overview of recent pre-clinical and clinical results in NK cell therapies is provided based on unstimulated, cytokine-activated, as well as genetically engineered NK cells using chimeric antigen rece...

  17. IMPLEMENTATION OF ARTIFICIAL NEURAL NETWORK IN CONCURRENCY CONTROL OF COMPUTER INTEGRATED MANUFACTURING(CIM) DATABASE

    OpenAIRE

    P. Raviram; R.S.D. Wahidabanu

    2008-01-01

    Manufacturing database store large amount of interrelated data. The designers access specific information or group of information in the data. Each designer accessing an entity tries to modify the design parameters meeting the requirements of different customers. Sister concerns of the same group of company will be modifying the data as per design requirements. When information is updated with new modification by different group of designers, what is the order in which modification of the dat...

  18. Microbiological Control of Flour-Manufacture: Dissemination of Mycotoxins Producing Fungi in Cereal Products

    OpenAIRE

    T.D. Doolotkeldieva

    2010-01-01

    Wheat grain and its products are widely consumed as fodder and basic daily food stuffs in Kyrgyzstan. Mycobiota is known to produce hazardous effects to a consumer since it produces mycotoxins. Henceforth, mycobiota starting from the field stage to flour, grain and flour samples were selected for mycological analysis from eight sites of flour manufacture: grain stored in storehouses before milling, mechanically cleaned grain, washed grain, grain dried and prepared for mill, roughly-milled flo...

  19. The Novel ''Controlled Intermediate Nuclear Fusion'' and its Possible Industrial Realization as Predicted by Hadronic Mechanics and Chemistry

    CERN Document Server

    Santilli, R M

    2006-01-01

    In this note, we propose, apparently for the first time, a new type of controlled nuclear fusion called "intermediate" because occurring at energies intermediate between those of the ''cold'' and ''hot'' fusions, and propose a specific industrial realization. For this purpose: 1) We show that known limitations of quantum mechanics, quantum chemistry and special relativity cause excessive departures from the conditions occurring for all controlled fusions; 2) We outline the covering hadronic mechanics, hadronic chemistry and isorelativity specifically conceived, constructed and verified during the past two decades for new cleans energies and fuels; 3) We identify seven physical laws predicted by the latter disciplines that have to be verified by all controlled nuclear fusions to occur; 4) We review the industrial research conducted to date in the selection of the most promising engineering realization as well as optimization of said seven laws; and 5) We propose with construction details a specific {\\it hadron...

  20. Nanosphere Lithography: A Powerful Method for the Controlled Manufacturing of Nanomaterials

    Directory of Open Access Journals (Sweden)

    Pierre Colson

    2013-01-01

    Full Text Available The never-ending race towards miniaturization of devices induced an intense research in the manufacturing processes of the components of those devices. However, the complexity of the process combined with high equipment costs makes the conventional lithographic techniques unfavorable for many researchers. Through years, nanosphere lithography (NSL attracted growing interest due to its compatibility with wafer-scale processes as well as its potential to manufacture a wide variety of homogeneous one-, two-, or three-dimensional nanostructures. This method combines the advantages of both top-down and bottom-up approaches and is based on a two-step process: (1 the preparation of a colloidal crystal mask (CCM made of nanospheres and (2 the deposition of the desired material through the mask. The mask is then removed and the layer keeps the ordered patterning of the mask interstices. Many groups have been working to improve the quality of the CCMs. Throughout this review, we compare the major deposition techniques to manufacture the CCMs (focusing on 2D polystyrene nanospheres lattices, with respect to their advantages and drawbacks. In traditional NSL, the pattern is usually limited to triangular structures. However, new strategies have been developed to build up more complex architectures and will also be discussed.

  1. Chemistry control at Bruce NGS 'B' from constructed to commercial operation

    International Nuclear Information System (INIS)

    Pre-operational storage chemistry and flushing of the secondary side is described. The approach devised for Bruce NGS 'B' Unit 6 was unique for an Ontario Hydro Nuclear Unit. The significance of the improved Construction installation and Quality Assurance procedures, combined with those of Operations is identified. Secondary side chemistry during both commissioning and later operation is reported. It will be shown that the application of ALARA (As Low As is Reasonably Achievable) concept has resulted in tighter chemical specifications being met

  2. A novel triple-actuating mechanism of an active air mount for vibration control of precision manufacturing machines: experimental work

    International Nuclear Information System (INIS)

    With the goal of vibration control and isolation in a clean room, we propose a new type of air mount which consists of pneumatic, electromagnetic (EM), and magnetorheological (MR) actuators. The air mount is installed below a semiconductor manufacturing machine to reduce the adverse effects caused by unwanted vibration. The proposed mechanism integrates the forces in a parallel connection of the three actuators. The MR part is designed to operate in an air spring in which the EM part is installed. The control logic is developed with a classical method and a switching mode to avoid operational mismatch among the forces developed. Based on extended microprocessors, a portable, embedded controller is installed to execute both nonlinear logic and digital communication with the peripherals. The pneumatic forces constantly support the heavy weight of an upper structure and maintain the level of the air mount. The MR damper handles the transient response, while the EM controller reduces the resonance response, which is switched mutually with a threshold. Vibration is detected by laser displacement sensors which have submicron resolution. The impact test results of three tons load weight demonstrate practical feasibility by showing that the proposed triple-actuating mechanism can reduce the transient response as well as the resonance in the air mount, resulting in accurate motion of the semiconductor manufacturing machine. (technical note)

  3. Development of manufacturing method of excess oxygen controlled ODS martensitic steel

    International Nuclear Information System (INIS)

    ODS martensitic steel is a prospective candidate cladding material for the advanced Fast Breeder Reactor (FBR) core components. A previous result showed that the high temperature strengths were deteriorated by the oxide particle coarsening and the reduction of the residual-alpha grains as excess oxygen (Ex.O) increased. In this study, the manufacturing conditions for reducing excess oxygen were examined in order to obtain the target strength. High excess oxygen steels with higher Y2O3 addition were also manufactured with the intention of manufacturing the steel which has both fully martensitic microstructure and enough high temperature strength. The derived results can be summarized as follows. (1) It was shown that 0.04wt% excess oxygen was brought from the pre-alloyed raw powders, and 0.04-0.1 wt% excess oxygen was mixed in the powders during the Mechanical Allowing (MA). (2) It was shown that excess oxygen could be reduced less than 0.1wt% by applying an ultra high purity Ar gas (99.9999wt%Ar) to MA atmosphere as well as reducing the agitating energy by using pin agitator with shorter length. (3) Residual alpha-grains and transformed alpha-grains were mixed in the furnace-cooled low excess oxygen steels (2O3 and excess oxygen-added steels (E1, E2). However enough high temperature strength are not expected in these steels because the Vickers hardness of these steels after the furnace-cooling (FC) or normalizing and tempering (NT) are apparently low. (author)

  4. Plasma monitoring and PECVD process control in thin film silicon-based solar cell manufacturing

    Directory of Open Access Journals (Sweden)

    Gabriel Onno

    2014-02-01

    Full Text Available A key process in thin film silicon-based solar cell manufacturing is plasma enhanced chemical vapor deposition (PECVD of the active layers. The deposition process can be monitored in situ by plasma diagnostics. Three types of complementary diagnostics, namely optical emission spectroscopy, mass spectrometry and non-linear extended electron dynamics are applied to an industrial-type PECVD reactor. We investigated the influence of substrate and chamber wall temperature and chamber history on the PECVD process. The impact of chamber wall conditioning on the solar cell performance is demonstrated.

  5. Data processing technologies and diagnostics for water chemistry and corrosion control in nuclear power plants (DAWAC). Additional information. Report of a coordinated research project 2001-2005

    International Nuclear Information System (INIS)

    The CD-ROM attached to the printed version of TECDOC 1505 'Data Processing Technologies and Diagnostics for Water Chemistry and Corrosion Control in Nuclear Power Plants (DAWAG)' includes the report itself, detailed progress reports of three research coordination meetings (Annexes I-III) and the final country reports. This publication provides information on the current status and development trends in monitoring, diagnostics and control of water chemistry and corrosion of core and primary circuit materials in water cooled power reactors. It summarizes the results of an IAEA Coordinated Research Project and focuses on the methods for development, qualification and implementation of water chemistry expert systems at nuclear power plants. These systems are needed to have full benefit from using on-line sensors in real time mode when sensor signals, and other chemistry and operational data, are collected and continuously analysed with data acquisition and evaluation software. Technical knowledge was acquired in water chemistry control techniques (grab sampling, on-line monitoring, data collecting and processing, etc), plant chemistry and corrosion diagnostics, plant monitoring (corrosion, chemistry, activity)and plant chemistry improvement (analytical models and practices). This publication covers contributions from leading experts in water chemistry/corrosion, representing organizations from 16 countries with the largest nuclear capacities

  6. Water Chemistry Control System for Recovery of Damaged and Degraded Spent Fuel

    International Nuclear Information System (INIS)

    The International Atomic Energy Agency (IAEA) and the government of Serbia have led the project co-sponsored by the U.S, Russia, European Commission, and others to repackage and repatriate approximately 8000 spent fuel elements from the RA reactor fuel storage basins at the VINCA Institute of Nuclear Sciences to Russia for reprocessing. The repackaging and transportation activities were implemented by a Russian consortium which includes the Sosny Company, Tekhsnabeksport (TENEX) and Mayak Production Association. High activity of the water of the fuel storage basin posed serious risk and challenges to the fuel removal from storage containers and repackaging for transportation. The risk centered on personnel exposure, even above the basin water, due to the high water activity levels caused by Cs-137 leached from fuel elements with failed cladding. A team of engineers from the U.S. DOE-NNSA's Global Threat Reduction Initiative, the Vinca Institute, and the IAEA performed the design, development, and deployment of a compact underwater water chemistry control system (WCCS) to remove the Cs-137 from the basin water and enable personnel safety above the basin water for repackaging operations. Key elements of the WCCS system included filters, multiple columns containing an inorganic sorbent, submersible pumps and flow meters. All system components were designed to be remotely serviceable and replaceable. The system was assembled and successfully deployed at the Vinca basin to support the fuel removal and repackaging activities. Following the successful operations, the Cs-137 is now safely contained and consolidated on the zeolite sorbent used in the columns of the WCCS, and the fuel has been removed from the basins. This paper reviews the functional requirements, design, and deployment of the WCCS. (author)

  7. Microbiological Control of Flour-Manufacture: Dissemination of Mycotoxins Producing Fungi in Cereal Products

    Directory of Open Access Journals (Sweden)

    T.D. Doolotkeldieva

    2010-03-01

    Full Text Available Wheat grain and its products are widely consumed as fodder and basic daily food stuffs in Kyrgyzstan. Mycobiota is known to produce hazardous effects to a consumer since it produces mycotoxins. Henceforth, mycobiota starting from the field stage to flour, grain and flour samples were selected for mycological analysis from eight sites of flour manufacture: grain stored in storehouses before milling, mechanically cleaned grain, washed grain, grain dried and prepared for mill, roughly-milled flour, first grade flour and high grade flour. The samples were analyzed using classical mycological and immunoassay methods in order to detect mycotoxins producing fungi species. We isolated overall 27 species belonging to 7 genera. Mycotoxins producing species like Aspergillus flavus, Aspergillus ochraceus and Penicillium cyclopium were detected in the stored grains and in mechanically-cleaned grains. The species of Penicillium, Alternaria and Fusarium genera dominated in roughly-milled flour samples, so this site of flour manufacture still has a risk and danger of contamination with mycotoxins producing fungus. Only the final product i.e. the high grade flour lacked any fungal contamination. We recommend to scrutinize flour samples at the last stages of processing, particularly in the mills like В1, С1 and С4.

  8. Review of best available techniques for the control of pollution from the combustion of fuels manufactured from or including waste

    International Nuclear Information System (INIS)

    This report is a technical review of the techniques available for controlling pollution from combustion processes burning fuels (over 3 MW thermal input) manufactured from or including the following: Waste and recovered oil; Refuse derived fuel; Rubber tyres and other rubber waste; Poultry litter; Wood and straw. This review forms the basis for the revision of the Chief Inspector's Guidance Notes referring to the prescribed processes listed with special emphasis on recommending achievable releases to all environmental media. In formulating achievable releases account is taken of technologies in operation in the UK and overseas. (UK)

  9. Operation and control of flow manufacturing based on constraints management for high-mix/low-volume production

    Institute of Scientific and Technical Information of China (English)

    Zailin GUAN; Yunfang PENG; Li MA; Chaoyong ZHANG; Peigen LI

    2008-01-01

    The existing technology of flow manufacturing, which is mainly appropriate for high volume and repetitive production, is proven difficult to be applied in high-mix/ low-volume environments. To adapt lean production into the latter, a new type of flow manufacturing is proposed based on flow path management technology. This paper first describes the general operation framework of the pro-posed new mode. The main idea is the dynamic formation of adaptable virtual production lines (called flow paths) corresponding to different product families. The applica-tion of different theories of constraints/drum-buffer-rope (TOC/DBR) control policies depends on the differences in scope of variety and scale of demand for these product families. The overall architecture of the proposed mech-anism of constraint management-based operation and con-trol is introduced. For the implementation, a mathematical programming method is suggested for the dynamic plan-ning of flow paths, and a TOC/DBR 'path-specific' mech-anism with group scheduling is used for the control over each flow path. We also study other critical issues including the identification and management of resource bottlenecks, and the setting of the buffer size in the deployment of the TOC/DBR mechanism.

  10. Manufacturing Success

    Science.gov (United States)

    Reese, Susan

    2007-01-01

    According to the National Association of Manufacturers (NAM), "manufacturing is the engine that drives American prosperity". When NAM and its research and education arm, The Manufacturing Institute, released the handbook, "The Facts About Modern Manufacturing," in October 2006, NAM President John Engler noted, that manufacturing output in America…

  11. Implementation of a TMP Advanced Quality Control System at a Newsprint Manufacturing Plant

    Energy Technology Data Exchange (ETDEWEB)

    Sebastien Kidd

    2006-02-14

    This project provided for the implementation of an advanced, model predictive multi-variant controller that works with the mill that has existing distributed control system. The method provides real time and online predictive models and modifies control actions to maximize quality and minimize energy costs. Using software sensors, the system can predict difficult-to-measure quality and process variables and make necessary process control decisions to accurately control pulp quality while minimizing electrical usage. This method of control has allowed Augusta Newsprint Company to optimize the operation of its Thermo Mechanical Pulp mill for lower energy consumption and lower pulp quality variance.

  12. Reinventing Chemistry

    OpenAIRE

    Whitesides, George McClelland

    2015-01-01

    Chemistry is in a period of change, from an era focused on molecules and reactions, to one in which manipulations of systems of molecules and reactions will be essential parts of controlling larger systems. This Essay traces paths from the past to possible futures.

  13. 78 FR 17142 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-03-20

    ... correcting the January 16, 2013 (78 FR 3646), proposed rule entitled ``Current Good Manufacturing Practice..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk- Based... regulation for current good manufacturing practice in manufacturing, packing, or holding human food...

  14. Green chemistry

    International Nuclear Information System (INIS)

    The depletion of world fossil fuel reserves and the involvement of greenhouse gases in the global warming has led to change the industrial and energy policies of most developed countries. The goal is now to reserve petroleum to the uses where it cannot be substituted, to implement renewable raw materials obtained from plants cultivation, and to consider the biodegradability of molecules and of manufactured objects by integrating the lifetime concept in their expected cycle of use. The green chemistry includes the design, development and elaboration of chemical products and processes with the aim of reducing or eliminating the use and generation of harmful compounds for the health and the environment, by adapting the present day operation modes of the chemical industry to the larger framework of the sustainable development. In addition to biofuels, this book reviews the applications of green chemistry in the different industrial processes in concern. Part 1 presents the diversity of the molecules coming from renewable carbon, in particular lignocellulose and the biotechnological processes. Part 2 is devoted to materials and treats of the overall available technological solutions. Part 3 focusses on functional molecules and chemical intermediates, in particular in sugar- and fats-chemistry. Part 4 treats of biofuels under the aspects of their production and use in today's technologies. The last part deals with the global approaches at the environmental and agricultural levels. (J.S.)

  15. A strategy for achieving manufacturing statistical process control within a highly complex aerospace environment

    OpenAIRE

    Veira, Adryan; Khan, Khurshid; Farrell, Ian

    2013-01-01

    This paper presents a strategy to achieve process control and overcome the previously mentioned industry constraints by changing the company focus to the process as opposed to the product. The strategy strives to achieve process control by identifying and controlling the process parameters that influence process capability followed by the implementation of a process control framework that marries statistical methods with lean business process and change management principles. The reliability ...

  16. IMPLEMENTATION OF ARTIFICIAL NEURAL NETWORK IN CONCURRENCY CONTROL OF COMPUTER INTEGRATED MANUFACTURING(CIM DATABASE

    Directory of Open Access Journals (Sweden)

    P. Raviram

    2008-11-01

    Full Text Available Manufacturing database store large amount of interrelated data. The designers access specific information or group of information in the data. Each designer accessing an entity tries to modify the design parameters meeting the requirements of different customers. Sister concerns of the same group of company will be modifying the data as per design requirements. When information is updated with new modification by different group of designers, what is the order in which modification of the data has to be allowed. If simultaneous access of the information is done, how to maintain the consistency of the data. and a designer voluntarily corrupts the data, how to make sure the designer is responsible for the corruption of data. In any case if the transaction process corrupts the data, how to maintain the consistency of the data. Deleting the information wantedly can be identified with extra security for the data. However, when transaction protocol is not implemented properly, then corruption of data in the form of misleading information that showing less numerical value than what it has to be or showing more numerical than before updation. In this research work, we have proposed a neural network method for the managing the locks assigned to objects and the corresponding transactions are stored in a data structure. The main purpose of using the ANN is that it will require less memory in storing the lock information assigned to objects. We have attempted to use backpropagation algorithm for storing lock information when multi users are working on computer integrated manufacturing (CIM database.

  17. Chemistry control at Bruce N.G.S. 'B' from construction to commercial operation

    International Nuclear Information System (INIS)

    Pre-operational storage chemistry and flushing of the secondary side is described. The approach devised for Bruce N.G.S. 'B' Unit 6 was unique for an Ontario Hydro nuclear unit. The significance of the improved construction installation and quality assurance is identified. Secondary side chemistry during both commissioning and later operation is reported. It will be shown that the application of ALARA (As Low As is Reasonably Achievable) concept has resulted in tighter chemical specifications being met. (author). 11 refs., 6 tabs., 4 figs

  18. Primary water chemistry control at units of Paks Nuclear Power Plant

    International Nuclear Information System (INIS)

    The primary water chemistry of the four identical units of Paks Nuclear Power Plant has been developed based on Western-type PWR units, taking into consideration some Soviet-Russian modifications. The political changes in 90s have also influenced the water chemistry specifications and directions. At PWR units the transition operational modes have been developed while in case of VVER units - in lack of central uniform regulation - this question has become the competence and responsibility of each individual plant. This problem has resulted in separate water chemistry developments with a considerable time delay. The needs for life-time extensions all over the World have made the development of start-up and shut-down chemistry procedures extremely important, since they considerably influence the long term and safe operation of plants. The uniformly structured limit value system, the principles applied for the system development, and the logic schemes for actions to be taken are discussed in the paper, both for normal operation and transition modes. (author)

  19. Crevice chemistry estimation from bulk water chemistry

    International Nuclear Information System (INIS)

    Since the first PWR plant in Japan started commercial operation in 1970, 22 plants are running in Japan as of the end of 1994. The main purpose of secondary water chemistry control is to minimize the corrosion possibility of the secondary system equipment, especially steam generators (SG). To achieve this objective, much effort has been concentrated on improving secondary water chemistry control. As a result of this effort, the recent secondary water chemistry in Japanese plants is well maintained in every stage of operation. However, to ensure and improve the reliability of SG, it is necessary to control crevice environments, which are located at tube/tube support plate intersections and under the sludge pile on the tube sheet. According to recent crevice monitoring examination results, the concentration behavior impurities in SG bulk water at the crevice is different for each species, and SG bulk water and crevice chemical compositions are not always equal. From these results, to control the crevice chemistry, improving bulk water chemistry control methods and a new type of molar ratio control index is needed. This paper introduces a brief summary of a recent crevice chemistry evaluation technique and bulk water chemistry control method, which is employed for crevice chemistry control, based on crevice monitoring examination results

  20. Heat Transfer Salts for Nuclear Reactor Systems - Chemistry Control, Corrosion Mitigation, and Modeling

    International Nuclear Information System (INIS)

    -evaluate thermophysical properties of flibe and flinak. Pacific Northwest National Laboratories has focused on evaluating the fluorinating gas nitrogen trifluoride as a potential salt purification agent. Work there was performed on removing hydroxides and oxides from flinak salt under controlled conditions. Lastly, the University of California Berkeley has spent considerable time designing and simulating reactor components with fluoride salts at high temperatures. Despite the hurdles presented by the innate chemical hazards, considerable progress has been made. The stage has been set to perform new research on salt chemical control which could advance the fluoride salt cooled reactor concept towards commercialization. What were previously thought of as chemical undesirable, but nuclear certified, alloys have been shown to be theoretically compatible with fluoride salts at high temperatures. This preliminary report has been prepared to communicate the construction of the basic infrastructure required for flibe, as well as suggest original research to performed at the University of Wisconsin. Simultaneously, the contents of this report can serve as a detailed, but introductory guide to allow anyone to learn the fundamentals of chemistry, engineering, and safety required to work with flibe salt.

  1. Heat Transfer Salts for Nuclear Reactor Systems - Chemistry Control, Corrosion Mitigation, and Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, Mark; Sridharan, Kumar; Morgan, Dane; Peterson, Per; Calderoni, Pattrick; Scheele, Randall; Casekka, Andrew; McNamara, Bruce

    2015-01-22

    -evaluate thermophysical properties of flibe and flinak. Pacific Northwest National Laboratories has focused on evaluating the fluorinating gas nitrogen trifluoride as a potential salt purification agent. Work there was performed on removing hydroxides and oxides from flinak salt under controlled conditions. Lastly, the University of California Berkeley has spent considerable time designing and simulating reactor components with fluoride salts at high temperatures. Despite the hurdles presented by the innate chemical hazards, considerable progress has been made. The stage has been set to perform new research on salt chemical control which could advance the fluoride salt cooled reactor concept towards commercialization. What were previously thought of as chemical undesirable, but nuclear certified, alloys have been shown to be theoretically compatible with fluoride salts at high temperatures. This preliminary report has been prepared to communicate the construction of the basic infrastructure required for flibe, as well as suggest original research to performed at the University of Wisconsin. Simultaneously, the contents of this report can serve as a detailed, but introductory guide to allow anyone to learn the fundamentals of chemistry, engineering, and safety required to work with flibe salt.

  2. A livelock control policy for a flexible manufacturing system modeling with a subclass of generalized Petri nets

    Directory of Open Access Journals (Sweden)

    C.Q. Hou

    2014-12-01

    Full Text Available Livelocks, like deadlocks, can result in the serious problems in running process of flexible manufacturing systems (FMSs as well. Current deadlock control policies based on the approaches of siphon detection and control, cannot cope with livelocks in a system of sequential systems with shared resources (S4R, a typical subclass of Petri nets that can model FMSs. On the basis of the mixed integer programming method, this study proposes a livelock control policy (LCP that can not only solve the new smart siphons (NSSs associated with livelocks or deadlocks in an S4R system directly, but also make the solved NSSs max′-controlled by adding the corresponding control places (CPs. As a result, an original S4R system with livelocks or deadlocks can be turned into the live controlled one in which no NSSs can be found. The related theoretical analysis and several examples are given to demonstrate the proposed LCP. Compared with the existing methods in the literature, the proposed one is more general and powerful.

  3. Effect of chronic and subchronic organic solvents exposure on balance control of workers in plant manufacturing adhesive materials.

    Science.gov (United States)

    Herpin, Guillaume; Gargouri, Imed; Gauchard, Gérome C; Nisse, Catherine; Khadhraoui, Moncef; Elleuch, Boubaker; Zmirou-Navier, Denis; Perrin, Philippe P

    2009-02-01

    High-level occupational exposure to volatile organic solvents may elicit neurotoxic effects, especially on central and peripheral structures involved in balance ability. Studies on balance control in relation with exposure levels close to the threshold limit values are scarce. This study aimed to assess the neurotoxic effects of chronic and subchronic exposure to organic solvents among workers in plant manufacturing adhesive materials. Balance control was evaluated in 18 subjects, mainly exposed to n-hexane and toluene, with current median exposure levels of 222 and 102 mg/m(3), respectively, and a median exposure duration of 21 years, and in 32 nonexposed controls, using posturography tests with and without sensory conflicting situations. Tests were undergone at the beginning of the work shift (chronic exposure) following a week end, and after 72 h (subchronic exposure). Balance control performance was lower in chronically exposed workers compared to controls, and got worse after subchronic exposure, particularly during situations, where vestibular information was important. Our study suggests that a low-level and prolonged exposure to volatile organic solvents, mainly n-hexane and toluene, in the workplace is associated with deleterious central effects involved in postural regulation. This neurotoxicity is characterized by difficulties to use the most relevant information to control balance, leading to altered management of sensory conflicting situations. PMID:19384580

  4. 78 FR 33443 - Manufacturer of Controlled Substances; Notice of Registration; Alltech Associates, Inc.

    Science.gov (United States)

    2013-06-04

    ... FR 12103, Alltech Associates, Inc., 2051 Waukegan Road, Deerfield, Illinois 60015, made application... basic classes of controlled substances: Drug Schedule 5-Methoxy-N-N-dimethyltryptamine (7431)..... I...

  5. 77 FR 67398 - Manufacturer of Controlled Substances Notice of Application; National Center For Natural Products...

    Science.gov (United States)

    2012-11-09

    ... the following basic classes of controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to cultivate marihuana for the National Institute on Drug Abuse...

  6. 78 FR 69132 - Manufacturer of Controlled Substances, Notice of Application, National Center for Natural...

    Science.gov (United States)

    2013-11-18

    ... the following basic classes of controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to cultivate marihuana in support of the National Institute on...

  7. 77 FR 47114 - Manufacturer of Controlled Substances; Notice of Application; AMRI Rensselaer, Inc.

    Science.gov (United States)

    2012-08-07

    ... following basic classes of controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols... distribution to its customers. In reference to drug code 7360 (Marihuana), the company plans to...

  8. 77 FR 38086 - Manufacturer of Controlled Substances; Notice of Application; Chemica

    Science.gov (United States)

    2012-06-26

    ... methamphetamine will not be sold as a commercial product. The company plans to utilize a bulk active pharmaceutical ingredient (API), as an intermediate for the development of another controlled substance,...

  9. Shippingport Atomic Power Station steam generator tube damage and water chemistry control (1965--1975)

    International Nuclear Information System (INIS)

    The four stainless steel tubed steam generators in the Shippingport Atomic Power Station were replaced in 1964 with larger, horizontal, NiCrFe Alloy 600 tubed units consistent with a power uprating of the plant. Each of the four Alloy 600 tubed units experienced tube leakage attributed to corrosion by water treatment chemicals (sodium phosphates) which concentrated locally on the tubes in inadequately flushed crevices. Corrective and preventive actions include tube plugging, flow blockage, conversion to all-volatile (hydrazine-morpholine) chemistry and replacement of the two steam generators with the straight tube design. Eddy current inspection after four years of all-volatile chemistry use showed a diminished rate of crevice corrosion and no tube denting

  10. Control and Characterization of Titanium Dioxide Morphology: Applications in Surface Organometallic Chemistry

    KAUST Repository

    Jeantelot, Gabriel

    2014-05-01

    Surface Organometallic Chemistry leads to the combination of the high activity and specificity of homogeneous catalysts with the recoverability and practicality of heterogeneous catalysts. Most metal complexes used in this chemistry are grafted on metal oxide supports such as amorphous silica (SiO2) and γ-alumina (Al2O3). In this thesis, we sought to enable the use of titania (TiO2) as a new support for single-site well-defined grafting of metal complexes. This was achieved by synthesizing a special type of anatase-TiO2, bearing a high density of identical hydroxyl groups, through hydrothermal synthesis then post-treatment under high vacuum followed by oxygen flow, and characterized by several analytical techniques including X-ray diffraction, transmission electron microscopy, infrared spectroscopy and nuclear magnetic resonance. Finally, as a proof of concept, the grafting of vanadium oxychloride (VOCl3) was successfully attempted.

  11. A comparison of inventory control policies for a joint manufacturing/Remanufacturing environment with remanufacturing yield loss

    NARCIS (Netherlands)

    Z.P. Bayindir (Pelin); R.H. Teunter (Ruud); R. Dekker (Rommert)

    2005-01-01

    textabstractWe consider a joint manufacturing / remanufacturing environment with remanufacturing yield loss. Demand and return follow independent stationary Poisson processes. Returns can be disposed off upon arrival to the system. Manufacturing and remanufacturing operations performed in the same f

  12. Control tools for flow chemistry processing and their application to the synthesis of bromodomain inhibitors

    OpenAIRE

    Ingham, Richard Jeremy

    2014-01-01

    Flow chemistry and continuous processing techniques are now frequently used in synthetic laboratories, taking advantage of the ability to contain reactive or hazardous intermediates and to perform moderate scale-up processes for important compounds. However, only a limited number of methods and tools for connecting flow synthesis steps into a single protocol have been described, and as a result manual interventions are frequently required between consecutive stages. There are two main cha...

  13. Medição e controle do tempo de atravessamento em um sistema de manufatura Measurement and control of lead-time in a manufacturing system

    Directory of Open Access Journals (Sweden)

    Miguel Afonso Sellitto

    2008-04-01

    Full Text Available Este artigo apresenta um método para a medição do tempo de atravessamento e do inventário em processo em manufatura. A medição foi usada em processo de controle organizacional de manufatura, cuja variável controlada foi o tempo de atravessamento de ordens. Tal controle pode ser útil em estratégias de manufatura em que a competição é baseada no uso do tempo, a TBC (time-based competition. Apresentou-se o método de medição, que inclui elementos da teoria das filas, e considerações para a simplificação de arranjos produtivos de manufatura. Para testar e refinar o método, estudou-se um caso em manufatura calçadista. Foram coletados dados de remessas e obtido, por análise estatística e simulação computacional, o comportamento da variável aleatória tempo de atravessamento de remessas. Como a medição foi inferior ao objetivo de desempenho, partiu-se para o controle, fazendo um diagnóstico que apontou efeitos indesejáveis observados que foram endereçados por ações corretivas implementadas. Para verificar a eficácia das ações, nova coleta foi feita. Desta vez, o objetivo de desempenho das entregas foi atendido, fechando um ciclo de controle. Os resultados foram discutidos, chegando-se a conclusões e alternativas de continuidade.This paper presents a method for the measurement of the lead-time and work-in-process in manufacturing. The measurement was used in an organizational control process in manufacturing, in which the controlled variate was the order lead-time. This kind of control can be useful in manufacture strategies formulated to compete in TBC (time-based competition. We presented the method, who includes elements from the queuing theory, and concerns about simplifying complex manufacturing arrays, in order to facilitate the analysis. In order to test and refine the method, we studied a case in a footwear manufacture system. We collected data from orders and, by statistical techniques and computational

  14. 78 FR 64735 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-10-29

    ... 16, 225, 500 et al. Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive... Administration 21 CFR Parts 16, 225, 500, 507, and 579 RIN 0910-AG10 Current Good Manufacturing Practice and..., and Cosmetic Act (the FD&C Act) to establish requirements for current good manufacturing practice...

  15. 78 FR 3646 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-01-16

    ... safe manufacturing, processing, packing, and holding of LACF (44 FR 16209, March 16, 1979). The second..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk- Based..., Subpart A) D. Proposed Revisions to Current Good Manufacturing Practice Requirements of Part 110...

  16. Controlling quality of ferroalloys and alloying additives in the manufacture of nickel alloys for nuclear applications

    International Nuclear Information System (INIS)

    Nickel alloys supplied to the nuclear industry must meet strict requirements for quality and traceability of constituents. Ensuring that end products meet those requirements involves careful control of the raw materials used in melting the alloys. Especially important is an effective system of quality control for purchasing and consuming ferroalloys and alloying additives. Development and operation of such a system requires (1) adequate specifications, (2) good relations with suppliers, (3) an approved-suppliers list, (4) formal receiving inspection, and (5) backup surveillance during processing

  17. Secondary water chemistry control practices and results of the Japanese PWR plants

    International Nuclear Information System (INIS)

    In Japan, since the start of the operation of the first PWR plant, Mihama Unit-1 in 1970, 24 PWR plants have been built by 2010, and all of them are in operation. Due to the plant-specific needs of management, and by flexibly incorporating the state-of-the-art insights into the design, the system configurations of the plants vary so many as 15 types. Meanwhile, the geographical feature of Japan makes all the Japanese PWR plants to have condensers cooled by sea water, and all the plants have a common system with a full-flow Condensate Polisher System (CPS). To prevent corrosion, continued improvements of the secondary water chemistry management has been performed like other countries, and one of the major features of the Japanese PWR plants is an enhanced provision for the condenser leakage. The water quality of SG (Steam Generator) has been significantly improved by the provision for the sea water leakage, in combination with other improvements in water chemistry management. Also in Japan, almost all of the treatments of the spent polisher resin and the wastewater are performed within the power plant sites. To facilitate the treatment of the waste water and the regeneration of the spent resins, either ammonia or ETA (Ethanol Amine) is selected as the pH adjustment agent for the secondary system water. Also at the ammonia treatment, high pH accomplishes the inhibition of the piping wall thinning and the lower iron transportation into SGs. In addition, the iron transported into the SG is removed by the chemical conditioning treatment called ASCA (Advanced Scale Conditioning Agent). This provides the effective recovery of the SG heat-transfer performance, and the improved SG support plate BEC (Broached Egg Crate) hole blockage rates. Basically in Japan, the secondary water chemistry management has been improved based on a single basic specification, for the variety of the plant configurations, with the plant-specific investigations and analyses. This paper summarizes

  18. Adaptive sliding mode control of the A-axis used for blisk manufacturing

    Directory of Open Access Journals (Sweden)

    Zhao Pengbing

    2014-06-01

    Full Text Available As a key assembly in the 5-axis CNC machine tools, positioning precision of the A-axis directly affects the machining accuracy and surface quality of the parts. First of all, mechanical structure and control system of the A-axis are designed. Then, considering the influence of nonlinear friction, backlash, unmodeled dynamics, uncertain cutting force and other external disturbance on the control precision of the A-axis, an adaptive sliding mode control (ASMC based on extended state observer (ESO is proposed. ESO is employed to estimate the state variables of the unknown system and an adaptive law is adopted to compensate for the input dead-zone caused by friction, backlash and other nonlinear characteristics. Finally, stability of the closed-loop system is guaranteed by the Lyapunov theory. Positioning experiments illustrate the perfect estimation of ESO and the stronger anti-interference and robustness of ASMC, which can improve the control precision of the A-axis by about 40 times. Processing experiments show that the ASMC can reduce the waviness, average error and roughness of the processed surface by 35.63%, 31.31% and 30.35%, respectively.

  19. Adaptive sliding mode control of the A-axis used for blisk manufacturing

    Institute of Scientific and Technical Information of China (English)

    Zhao Pengbing; Shi Yaoyao

    2014-01-01

    As a key assembly in the 5-axis CNC machine tools, positioning precision of the A-axis directly affects the machining accuracy and surface quality of the parts. First of all, mechanical structure and control system of the A-axis are designed. Then, considering the influence of nonlin-ear friction, backlash, unmodeled dynamics, uncertain cutting force and other external disturbance on the control precision of the A-axis, an adaptive sliding mode control (ASMC) based on extended state observer (ESO) is proposed. ESO is employed to estimate the state variables of the unknown system and an adaptive law is adopted to compensate for the input dead-zone caused by friction, backlash and other nonlinear characteristics. Finally, stability of the closed-loop system is guaran-teed by the Lyapunov theory. Positioning experiments illustrate the perfect estimation of ESO and the stronger anti-interference and robustness of ASMC, which can improve the control precision of the A-axis by about 40 times. Processing experiments show that the ASMC can reduce the waviness, average error and roughness of the processed surface by 35.63%, 31.31%and 30.35%, respectively.

  20. 77 FR 13633 - Manufacturer of Controlled Substances; Notice of Registration; National Center for Natural...

    Science.gov (United States)

    2012-03-07

    ... Register on October 7, 2011, 76 FR 62449, National Center for Natural Products Research-NIDA MProject... following basic classes of controlled substances: Drug Schedule Marihuana (7360) I Tetrahydrocannabinols (7370) I The company plans to cultivate marihuana for the National Institute on Drug Abuse for...

  1. 78 FR 23597 - Manufacturer of Controlled Substances, Notice of Registration, National Center for Natural...

    Science.gov (United States)

    2013-04-19

    ... November 9, 2012, 77 FR 67398, National Center for Natural Products Research-NIDA MProject, University of... classes of controlled substances: Drug Schedule Marihuana (7360) II Tetrahydrocannabinols (7370) II The company plans to cultivate marihuana for the National Institute on Drug Abuse for research approved by...

  2. X-ray topography as a process control tool in semiconductor and microcircuit manufacture

    Science.gov (United States)

    Parker, D. L.; Porter, W. A.

    1977-01-01

    A bent wafer camera, designed to identify crystal lattice defects in semiconductor materials, was investigated. The camera makes use of conventional X-ray topographs and an innovative slightly bent wafer which allows rays from the point source to strike all portions of the wafer simultaneously. In addition to being utilized in solving production process control problems, this camera design substantially reduces the cost per topograph.

  3. Disk Chemistry*

    OpenAIRE

    Thi Wing-Fai

    2015-01-01

    The chemical species in protoplanetary disks react with each other. The chemical species control part of the thermal balance in those disks. How the chemistry proceeds in the varied conditions encountered in disks relies on detailed microscopic understanding of the reactions through experiments or theoretical studies. This chapter strives to summarize and explain in simple terms the different types of chemical reactions that can lead to complex species. The first part of the chapter deals wit...

  4. Tuning of nanoparticle biological functionality through controlled surface chemistry and characterisation at the bioconjugated nanoparticle surface

    Science.gov (United States)

    Hristov, Delyan R.; Rocks, Louise; Kelly, Philip M.; Thomas, Steffi S.; Pitek, Andrzej S.; Verderio, Paolo; Mahon, Eugene; Dawson, Kenneth A.

    2015-12-01

    We have used a silica - PEG based bionanoconjugate synthetic scheme to study the subtle connection between cell receptor specific recognition and architecture of surface functionalization chemistry. Extensive physicochemical characterization of the grafted architecture is capable of capturing significant levels of detail of both the linker and grafted organization, allowing for improved reproducibility and ultimately insight into biological functionality. Our data suggest that scaffold details, propagating PEG layer architecture effects, determine not only the rate of uptake of conjugated nanoparticles into cells but also, more significantly, the specificity of pathways via which uptake occurs.

  5. Cold and controlled molecular collisions: a bridge from quantum physics to organic chemistry

    International Nuclear Information System (INIS)

    The fundamental dynamics of molecular collisions and reactions have challenged researchers for many years. This continues to drive the development of more informative experiments and more precise theoretical descriptions in physical chemistry and chemical physics. I will discuss two collision processes that we have studied with different techniques in my group. The first one is a fully quantum state-resolved inelastic collision, which we have achieved to study in a low-temperature ion trap. The second one is the elementary nucleophilic substitution reaction, for which we have been able to image and analyse several different reaction mechanisms. (author)

  6. QUALITY IMPROVEMENT USING STATISTICAL PROCESS CONTROL TOOLS IN GLASS BOTTLES MANUFACTURING COMPANY

    Directory of Open Access Journals (Sweden)

    Yonatan Mengesha Awaj

    2013-03-01

    Full Text Available In order to survive in a competitive market, improving quality and productivity of product or process is a must for any company. This study is about to apply the statistical process control (SPC tools in the production processing line and on final product in order to reduce defects by identifying where the highest waste is occur at and to give suggestion for improvement. The approach used in this study is direct observation, thorough examination of production process lines, brain storming session, fishbone diagram, and information has been collected from potential customers and company's workers through interview and questionnaire, Pareto chart/analysis and control chart (p-chart was constructed. It has been found that the company has many problems; specifically there is high rejection or waste in the production processing line. The highest waste occurs in melting process line which causes loss due to trickle and in the forming process line which causes loss due to defective product rejection. The vital few problems were identified, it was found that the blisters, double seam, stone, pressure failure and overweight are the vital few problems. The principal aim of the study is to create awareness to quality team how to use SPC tools in the problem analysis, especially to train quality team on how to held an effective brainstorming session, and exploit these data in cause-and-effect diagram construction, Pareto analysis and control chart construction. The major causes of non-conformities and root causes of the quality problems were specified, and possible remedies were proposed. Although the company has many constraints to implement all suggestion for improvement within short period of time, the company recognized that the suggestion will provide significant productivity improvement in the long run.

  7. Manufacturing, Structure Control, and Functional Testing of Ti-Nb-Based SMA for Medical Application

    Science.gov (United States)

    Prokoshkin, S.; Brailovski, V.; Dubinskiy, S.; Zhukova, Y.; Sheremetyev, V.; Konopatsky, A.; Inaekyan, K.

    2016-06-01

    This paper focuses on the development and characterization of Ni-free shape memory alloys, more specifically, Ti-Nb-based alloys for biomedical applications. It starts by describing the smelting technology used to produce small and medium size ingots of selected compositions. Thermomechanical treatments: structure interrelations are discussed next. Finally, the results of their mechanical, electrochemical, and in vitro cytotoxicity testing are presented to allow a general assessment of the mechanical, chemical, and biological aspects of compatibility of these alloys, and of the methods to control their functional properties.

  8. Quality Control in Automated Manufacturing Processes – Combined Features for Image Processing

    Directory of Open Access Journals (Sweden)

    B. Kuhlenkötter

    2006-01-01

    Full Text Available In production processes the use of image processing systems is widespread. Hardware solutions and cameras respectively are available for nearly every application. One important challenge of image processing systems is the development and selection of appropriate algorithms and software solutions in order to realise ambitious quality control for production processes. This article characterises the development of innovative software by combining features for an automatic defect classification on product surfaces. The artificial intelligent method Support Vector Machine (SVM is used to execute the classification task according to the combined features. This software is one crucial element for the automation of a manually operated production process. 

  9. Application of commercial sensor manufacturing methods for NOx/NH3 mixed potential sensors for emissions control

    Energy Technology Data Exchange (ETDEWEB)

    Brosha, Eric L [Los Alamos National Laboratory; Mukundan, Rangachary [Los Alamos National Laboratory; Nelson, Mark A [Los Alamos National Laboratory; Sekhar, Praveen [Los Alamos National Laboratory; Williamson, Todd [Los Alamos National Laboratory; Garzon, Fernando H [Los Alamos National Laboratory

    2009-01-01

    The purpose of this research effort is to develop a low cost on-board Nitrogen Oxide (NO{sub x})/Ammonia (NH{sub 3}) sensor that can not only be used for emissions control but has the potential to improve efficiency through better monitoring of the combustion process and feedback control in both vehicle and stationary systems. Over the past decade, Los AJamos National Laboratory (LANL) has developed a unique class of electrochemical gas sensors for the detection of carbon monoxide, hydrocarbons, hydrogen and nitrogen oxides. These sensors are based on the mixed-potential phenomenon and are a modification of the existing automotive lambda (oxygen) sensor and have the potential to meet the stringent sensitivity, selectivity and stability requirements of an on-board emissions/engine control sensor system. The current state of the art LANL technology is based on the stabilization of the electrochemical interfaces and relies on an externally heated, hand-made, tape cast device. We are now poised to apply our patented sensing principles in a mass production sensor platform that is more suitable for real world engine-out testing such as on dynamometers for vehicle applications and for exhaust-out testing in heavy boilers/SCR systems in power plants. In this present work, our goal is to advance towards commercialization of this technology by packaging the unique LANL sensor design in a standard automotive sensor-type platform. This work is being performed with the help of a leading US technical ceramics firm, utilizing commercial manufacturing techniques. Initial tape cast platforms with screen printed metal oxide and Pt sensor electrodes have shown promising results but also clearly show the need for us to optimize the electrode and electrolyte compositions/morphologies and interfaces of these devices in order to demonstrate a sensitive, selective, and stable NO{sub x} sensor. Our previous methods and routes to preparing stable and reproducible mixed potential sensors

  10. Application of articulated absolute co-ordinate measuring machine for quality control in manufacturing of ELM control coil

    International Nuclear Information System (INIS)

    Under India-EU collaboration, Institute for Plasma Research had undertaken an engineering feasibility initiative aimed at developing a 1:1 prototype Edge Localized Modes control coils (ELM CC) for Joint European Torus (JET). The ELM coils comprised of winding pack made of CuCrZr conductor encased in Inconel 625 casing. The ELM control coils are designed in saddle coil configuration having toroidal and poloidal curves similar to that of JET vacuum vessel. ELM coil are in-vessels coils forming the primary boundary with torus vacuum which demands stringent requirement for its quality aspects. The dimensional accuracies of winding pack and casing are critical for its encasing and remote assembly inside vacuum vessel. The articulated arm co-ordinate measuring machine (AACMM) has been extensively used for dimensional metrology of ELM CC from winding to its encasing. The inspection methodology and procedures using noncontact technique for ELM CC with AACMM has been developed and established with extensive trials. The winding pack, their formers and final ELM control coils has been systematically investigated for their dimensional accuracies with AACMM. The effectiveness of AACMM based evaluation for quality control in fabrication of 1:1 prototype of ELM CC has been presented in this paper. (author)

  11. Simulation-based design optimization and control of thick composite laminates manufactured by resin transfer molding

    Science.gov (United States)

    Michaud, Dennis J.

    2000-10-01

    Processing thick-sectioned composites (>1/2″ ) can be difficult due to the exothermic nature of the resin and the low thermal conductivity of the composite. This is particularly true for the Resin Transfer Molding process examined here. The temperature profile used to polymerize the resin, otherwise known as a "cure cycle," must be carefully chosen to reduce thermal gradients within the composite while ensuring satisfactory processing times. Instead of trial and error methods that are expensive, time consuming, and non-optimal, we propose a knowledge-based optimization strategy. In order to be effective, the optimization strategy requires an accurate simulation of the process and supplementary heuristic information. A 1-D finite difference cure simulation was used to simulate the process. Some of the simulation's model input parameters were found directly through experimentation. Other input parameters were identified using a least-squares approach to match the simulation to experimental data from seven test composites. Because an accurate residual stress model for the process was unavailable, a heuristic for predicting the quality of a composite, based on the progression of resin cure within the composite, was used. Four different global optimization schemes were studied: Random Walk, Simulated Annealing, Genetic Algorithms, and Evolutionary Strategies. The optimal cure cycle suggests heating the composite to initiate cure followed by a cooling stage to ensure inside-out curing. An extension of the Evolutionary Strategies optimization method was developed to account for the known variability in the simulation's input parameters and generate an optimum that can withstand some batch to batch variations. In addition to the suggested cure cycle, we propose to implement adaptive control. Through a sensitivity analysis of the optimal cure cycle, the conditions and manner of altering the cure cycle were identified. Furthermore, instead of relying on intrusive sensors

  12. A trial manufacture of cassette tape to standard MT data processing system controlled by microcomputer

    International Nuclear Information System (INIS)

    The data processing system controlled by a microcomputer has been developed for the purpose of data handling of cassette magnetic tape used as a recorder of pulse hight analyzer in market. This system has the following features; (1) This data acquisition system consists of a portable pulse hight analyzer and an audio-cassette magnetic tape recorder, which is low in price, light in weight and portable. (2) As the data processing part is composed by a microcomputer, one can easily deal with a different type of data code by a slight modification of a process program. (3) The processed output can be taken out to a standard 9 track 1600 BPI PE mode magnetic tape by a magnetic tape handler, and be available for a generally used bach-process computer. This report describes the hardware configuration and the process program in detail. Moreover, the operational manual, a sample operation and program lists are described in the appendix. (author)

  13. In situ optical diagnostic for monitoring or control of sodium diffusion in photovoltaics manufacturing

    Science.gov (United States)

    Li, Jian; Levi, Dean; Contreras, Miguel; Glynn, Stephen

    2015-09-15

    A method of fabricating a photovoltaic device 100, includes the steps of providing a glass substrate 102, depositing a molybdenum layer 104 on a surface of the glass substrate, directing light through the glass substrate to the near-substrate region of the molybdenum layer 206, detecting an optical property of the near-substrate region of the molybdenum layer after interaction with the incident light 208 and determining a density of the near-substrate region of the molybdenum layer from the detected optical property 210. A molybdenum deposition parameter may be controlled based upon the determined density of the near-substrate region of the molybdenum layer 218. A non-contact method measures a density of the near-substrate region of a molybdenum layer and a deposition chamber 300.

  14. Microsystems for enhanced control of cell behavior fundamentals, design and manufacturing strategies, applications and challenges

    CERN Document Server

    2016-01-01

    This handbook focuses on the entire development process of biomedical microsystems that promote special interactions with cells. Fundamentals of cell biology and mechanobiology are described as necessary preparatory input for design tasks. Advanced design, simulation, and micro/nanomanufacturing resources, whose combined use enables the development of biomedical microsystems capable of interacting at a cellular level, are covered in depth. A detailed series of chapters is then devoted to applications based on microsystems that offer enhanced cellular control, including microfluidic devices for diagnosis and therapy, cell-based sensors and actuators (smart biodevices), microstructured prostheses for improvement of biocompatibility, microstructured and microtextured cell culture matrices for promotion of cell growth and differentiation, electrophoretic microsystems for study of cell mechanics, microstructured and microtextured biodevices for study of cell adhesion and dynamics, and biomimetic microsystems (incl...

  15. Optimizing process time of laser drilling processes in solar cell manufacturing by coaxial camera control

    Science.gov (United States)

    Jetter, Volker; Gutscher, Simon; Blug, Andreas; Knorz, Annerose; Ahrbeck, Christopher; Nekarda, Jan; Carl, Daniel

    2014-03-01

    In emitter wrap through (EWT) solar cells, laser drilling is used to increase the light sensitive area by removing emitter contacts from the front side of the cell. For a cell area of 156 x 156 mm2, about 24000 via-holes with a diameter of 60 μm have to be drilled into silicon wafers with a thickness of 200 μm. The processing time of 10 to 20 s is determined by the number of laser pulses required for safely opening every hole on the bottom side. Therefore, the largest wafer thickness occurring in a production line defines the processing time. However, wafer thickness varies by roughly +/-20 %. To reduce the processing time, a coaxial camera control system was integrated into the laser scanner. It observes the bottom breakthrough from the front side of the wafer by measuring the process emissions of every single laser pulse. To achieve the frame rates and latency times required by the repetition rate of the laser (10 kHz), a camera based on cellular neural networks (CNN) was used where the images are processed directly on the camera chip by 176 x 144 sensor-processor-elements. One image per laser pulse is processed within 36 μs corresponding to a maximum pulse rate of 25 kHz. The laser is stopped when all of the holes are open on the bottom side. The result is a quality control system in which the processing time of a production line is defined by average instead of maximum wafer thickness.

  16. PWR Secondary Water Chemistry Control Status: A Summary of Industry Initiatives, Experience and Trends Relative to the EPRI PWR Secondary Water Chemistry Guidelines

    International Nuclear Information System (INIS)

    The latest revision of the EPRI Pressurized Water Reactor (PWR) Secondary Water Chemistry Guidelines was issued in February 2009. The Guidelines continue to focus on minimizing stress corrosion cracking (SCC) of steam generator tubes, as well as minimizing degradation of other major components / subsystems of the secondary system. The Guidelines provide a technically-based framework for a plant-specific and effective PWR secondary water chemistry program. With the issuance of Revision 7 of the Guidelines in 2009, many plants have implemented changes that allow greater flexibility on startup. For example, the previous Guidelines (Revision 6) contained a possible low power hold at 5% power and a possible mid power hold at approximately 30% power based on chemistry constraints. Revision 7 has established a range over which a plant-specific value can be chosen for the possible low power hold (between 5% and 15%) and mid power hold (between 30% and 50%). This has provided plants the ability to establish significant plant evolutions prior to reaching the possible power hold; such as establishing seal steam to the condenser, placing feed pumps in service, or initiating forward flow of heater drains. The application of this flexibility in the industry will be explored. This paper also highlights the major initiatives and industry trends with respect to PWR secondary chemistry; and outlines the recent work to effectively address them. These will be presented in light of recent operating experience, as derived from EPRI's PWR Chemistry Monitoring and Assessment (CMA) program (which contains more than 400 cycles of operating chemistry data). (authors)

  17. Holonic Manufacturing Paint Shop

    Science.gov (United States)

    Lind, Morten; Roulet-Dubonnet, Olivier; Nyen, Per Åge; Gellein, Lars Tore; Lien, Terje; Skavhaug, Amund

    In pursuit of flexibility and agility within discrete manufacturing, the surrounding logistics and handling processes of a paint shop is under construction as a laboratory prototype application. Holonic Manufacturing seems to be a promising strategic paradigm and architecture to use for a system characterised by production logistics and control. This paper describes the physical devices to be used; the desired functionality; and the basic logic control designed. Additionally, the ideas for holonification based on the already designed logic control is presented.

  18. Daily quality control in computed radiography mammography using the manufacturer phantom

    Energy Technology Data Exchange (ETDEWEB)

    Jakubiak, Rosangela R.; Messias, Pricila C.; Oliveira, Carlla M., E-mail: requi@utfpr.edu.br [Technological Federal University of Parana (UTFPR), Curitiba, PR (Brazil). Academic Physics Dept.

    2011-07-01

    The quality control (QC) in mammography system involves a large amount of test tools, which implies a large space for storage and a high number of exposure. This work describes a QC system using a phantom, Fuji Computed Radiography (FCR) One Shot Phantom M Plus, that evaluates several parameters with just one exposure. The software offers tests with annual, semi-annual, quarterly, weekly and daily periodicity, and analyzes the conformities of the mammography equipment, image plate and cassettes. Because of the high number of tests, it was evaluated the daily test only for seven months in two mammography equipment. The test, through the software and its image, allows the analysis of ten parameters in QC. The evaluation of these parameters was realized by the average of the values provided by the software. Only one of the evaluated items showed not conformity, but this was observed and the necessary corrections were realized. The monitoring of use of FCR Mammography QC software with the FCR One Shot Phantom M Plus was realized and through this we could investigate that the quality program provided by the system is appropriate for the radiology services that has the Fuji Computed Radiography system. (author)

  19. On-line Measurements and Control of Viable Cell Density in Cell Culture Manufacturing Processes using Radio-frequency Impedance.

    Science.gov (United States)

    Carvell, John P; Dowd, Jason E

    2006-03-01

    In this work, radio-frequency (RF) impedance is reviewed as a method for monitoring and controlling cell culture manufacturing processes. It is clear from the many publications cited that RF Impedance is regarded as an accurate and reliable method for measuring the live cell bio-volume both on-line and off-line and the technology is also sutable for animal cells in suspension, attached to micro-carriers or immobilized in fixed beds. In cGMP production, RF Impedance is being used in three main areas. Firstly, it is being used as a control instrument for maintaining consistent perfusion culture allowing the bioreactor to operate under optimum conditions for maximum production of recombinant proteins. In the second application it has not replaced traditional off-line live cell counting techniques but it is being used as an additional monitoring tool to check product conformance. Finally, RF Impedance is being used to monitor the concentration of live cells immobilized on micro-carriers or packed beds in cGMP processes where traditional off-line live cell counting methods are inaccurate or impossible to perform. PMID:19003069

  20. Imaging techniques applied to quality control of civil manufactured goods obtained starting from ready-to-use mixtures

    Science.gov (United States)

    Bonifazi, Giuseppe; Castaldi, Federica

    2003-05-01

    Concrete materials obtained from the utilization of pre-mixed and ready to use products (central mix-concrete) are more and more used. They represent a big portion of the civil construction market. Such products are used at different scale, ranging from small scale works, as those commonly realized inside and house, an apartment, etc. or at big civil or industrial scale works. In both cases the problem to control the mixtures and the final work is usually realized through the analysis of properly collected samples. Through appropriate sampling it can be derived objective parameters, as size class distribution and composition of the constituting particulate matter, or mechanical characteristics of the sample itself. An important parameter not considered by the previous mentioned approach is "segregation", that is the possibility that some particulate materials migrate preferentially in some zones of the mixtures and/or of the final product. Such a behavior dramatically influences the quality of the product and of the final manufactured good. Actually this behavior is only studied adopting a human based visual approach. Not repeatable analytical procedures or quantitative data processing exist. In this paper a procedure fully based on image processing techniques is described and applied. Results are presented and analyzed with reference to industrial products. A comparison is also made between the new proposed digital imaging based techniques and the analyses usually carried out at industrial laboratory scale for standard quality control.

  1. Investigation of possibilities of application of neutron capture gamma-ray spectrometry for cement manufactures control

    International Nuclear Information System (INIS)

    Full text: Creation of system of Automatic Management of Technological Processes in cement industry still remains an actual problem, solution of which leads to increase in volume and improvement in the quality of the ready product, and also gives opportunity to effective use of electro energy and raw material resources. In preparation of cement acute stands the question of realization of operative control of the content of main technologically important elements: like Ca, Mg, Fe, Si and Al in the initial raw material and different content must be determined on the technological stream. Among existing analytical methods, nuclear physics method based on prompt gamma radiation of neutron capture spectrometry is one of the better possibilities/1,2/. In this work, results of investigation of possibilities of express determination of technological important elements: Ca, Mg, Fe, Si and Al in the initial raw material by the method of neutron capture prompt gamma - ray spectrometry. Laboratory model of low power radionuclide (252Cf) - source of neutrons with the yield of 5x106 neutron/sec. Measuring equipment consists of semiconductor Ge (Li) - detector with volume of sensitive crystal, 40 sm3 and energy resolution of 4 keV on the line of 60Co with the energy of 1333 keV and multichannel pulse analyzers AI-1024-95. Possibility of express determination of concentration of technologically important elements in the initial raw material of Kyzylkum by means of using neutron capture gamma radiation spectrometry with parameters meeting production requirements of cement industry of Uzbekistan

  2. Design of Biomedical and Biofunctional Polymers by Use of Living/Controlled Polymerizations and "Click" Chemistry

    DEFF Research Database (Denmark)

    Hvilsted, Søren

    employed as a viable scaffold for design of several novel materials with intriguing, potentially therapeutic and biological properties. Living ROP strategies have afforded telechelic PCLs that can be equipped with various functional groups including “clickable” moieties or turned into macromonomers...... the gold clusters. The former may be addressed by devising polymeric ligands with desirable features and functional groups. Thus the preparation of the PCL-b-PAA corona will be outlined. The second effort is the ligation of biologically active moieties to the termini of the hydrophobic PCL chain to......The lecture will address recent research activities aiming at developing novel biomacromolecular materials with unsurpassed properties by use of the proper synthetic tools where various “click” chemistry approaches play a key prominent role. Two entirely different themes will be elaborated with...

  3. Functional group and individual maceral chemistry of high volatile bituminous coals from southern Indiana: Controls on coking

    Science.gov (United States)

    Walker, R.; Mastalerz, Maria

    2004-01-01

    The individual maceral chemistries of two Pennsylvanian, high volatile bituminous coals, the Danville Coal Member (Dugger Formation, R o=0.55%) and the Lower Block Coal Member (Brazil Formation, R o=0.56%) of Indiana, were investigated using electron microprobe and Fourier Transform Infrared Spectrometry (FTIR) techniques, with the purpose of understanding differences in their coking behavior. Microprobe results reveal that carbon contents are highest in inertinite and sporinite, followed by desmocollinite and telocollinite. Oxygen and organic nitrogen are most abundant in telocollinite and desmocollinite; sporinite and inertinite contain lesser amounts of these two elements. Organic sulfur contents are highest in sporinite, lowest in inertinite, and intermediate in desmocollinite and telocollinite. Vitrinites within the Danville and Lower Block coals are very similar in elemental composition, while Lower Block inertinites and sporinites have higher carbon, lower oxygen, and sulfur contents which, when combined with the inertinite-and sporinite-rich composition of the Lower Block seam, strongly influences its whole coal chemistry. Fourier transform infrared spectrometry revealed greater aromatic hydrogen in the Lower Block coal, along with higher CH2/CH3 ratios, which suggest that liptinites contribute considerable amounts of long-chain, unbranched aliphatics to the overall kerogen composition of the Lower Block coal. Long-chain, unbranched aliphatics crack at higher temperatures, producing tar and oily byproducts during coking; these may help increase Lower Block plasticity. Electron microprobe and FTIR results indicate that individual maceral chemistries, combined with the maceral composition of the seam, are the primary control of better coking properties of the Lower Block coal. ?? 2003 Elsevier B.V. All rights reserved.

  4. Bad chemistry

    OpenAIRE

    Petsko, Gregory A

    2004-01-01

    General chemistry courses haven't changed significantly in forty years. Because most basic chemistry students are premedical students, medical schools have enormous influence and could help us start all over again to create undergraduate chemistry education that works.

  5. Precision manufacturing

    CERN Document Server

    Dornfeld, David

    2008-01-01

    Today there is a high demand for high-precision products. The manufacturing processes are now highly sophisticated and derive from a specialized genre called precision engineering. Precision Manufacturing provides an introduction to precision engineering and manufacturing with an emphasis on the design and performance of precision machines and machine tools, metrology, tooling elements, machine structures, sources of error, precision machining processes and precision process planning. As well as discussing the critical role precision machine design for manufacturing has had in technological developments over the last few hundred years. In addition, the influence of sustainable manufacturing requirements in precision processes is introduced. Drawing upon years of practical experience and using numerous examples and illustrative applications, David Dornfeld and Dae-Eun Lee cover precision manufacturing as it applies to: The importance of measurement and metrology in the context of Precision Manufacturing. Th...

  6. EPRI BWR Water Chemistry Guidelines Revision

    International Nuclear Information System (INIS)

    BWRVIP-190: BWR Water Chemistry Guidelines – 2008 Revision has been revised. The revision committee consisted of U.S. and non-U.S. utilities (members of the BWR Vessel and Internals Protection (BWRVIP) Mitigation Committee), reactor system manufacturers, fuel suppliers, and EPRI and industry experts. The revised document, BWRVIP-190 Revision 1, was completely reformatted into two volumes, with a simplified presentation of water chemistry control, diagnostic and good practice parameters in Volume 1 and the technical bases in Volume 2, to facilitate use. The revision was developed in parallel and in coordination with preparation of the Fuel Reliability Guidelines Revision 1: BWR Fuel Cladding Crud and Corrosion. Guidance is included for plants operating under normal water chemistry (NWC), moderate hydrogen water chemistry (HWC-M), and noble metal application (GE-Hitachi NobleChem™) plus hydrogen injection. Volume 1 includes significant changes to BWR feedwater and reactor water chemistry control parameters to provide increased assurance of intergranular stress corrosion cracking (IGSCC) mitigation of reactor materials and fuel reliability during all plant conditions, including cold shutdown (≤200°F (93°C)), startup/hot standby (>200°F (93°C) and ≤ 10%) and power operation (>10% power). Action Level values for chloride and sulfate have been tightened to minimize environmentally assisted cracking (EAC) of all wetted surfaces, including those not protected by hydrogen injection, with or without noble metals. Chemistry control guidance has been enhanced to minimize shutdown radiation fields by clarifying targets for depleted zinc oxide (DZO) injection while meeting requirements for fuel reliability. Improved tabular presentations of parameter values explicitly indicate levels at which actions are to be taken and required sampling frequencies. Volume 2 provides the technical bases for BWR water chemistry control for control of EAC, flow accelerated corrosion

  7. Hot-electron-mediated surface chemistry: toward electronic control of catalytic activity.

    Science.gov (United States)

    Park, Jeong Young; Kim, Sun Mi; Lee, Hyosun; Nedrygailov, Ievgen I

    2015-08-18

    Energy dissipation at surfaces and interfaces is mediated by excitation of elementary processes, including phonons and electronic excitation, once external energy is deposited to the surface during exothermic chemical processes. Nonadiabatic electronic excitation in exothermic catalytic reactions results in the flow of energetic electrons with an energy of 1-3 eV when chemical energy is converted to electron flow on a short (femtosecond) time scale before atomic vibration adiabatically dissipates the energy (in picoseconds). These energetic electrons that are not in thermal equilibrium with the metal atoms are called "hot electrons". The detection of hot electron flow under atomic or molecular processes and understanding its role in chemical reactions have been major topics in surface chemistry. Recent studies have demonstrated electronic excitation produced during atomic or molecular processes on surfaces, and the influence of hot electrons on atomic and molecular processes. We outline research efforts aimed at identification of the intrinsic relation between the flow of hot electrons and catalytic reactions. We show various strategies for detection and use of hot electrons generated by the energy dissipation processes in surface chemical reactions and photon absorption. A Schottky barrier localized at the metal-oxide interface of either catalytic nanodiodes or hybrid nanocatalysts allows hot electrons to irreversibly transport through the interface. We show that the chemicurrent, composed of hot electrons excited by the surface reaction of CO oxidation or hydrogen oxidation, correlates well with the turnover rate measured separately by gas chromatography. Furthermore, we show that hot electron flows generated on a gold thin film by photon absorption (or internal photoemission) can be amplified by localized surface plasmon resonance. The influence of hot charge carriers on the chemistry at the metal-oxide interface are discussed for the cases of Au, Ag, and Pt

  8. Studies of manufacturing controlled-release graphene acid and catalyzing synthesis of chalcone with Claisen-Schmidt condensation reaction

    Science.gov (United States)

    Li, Jihui; Feng, Jia; Li, Mei; Wang, Qiaolian; Su, Yumin; Jia, Zhixin

    2013-07-01

    In the paper, graphene acid (GA) was manufactured, using flake graphite as raw material, and the acidity and the structure of GA were characterized as well as. Then, chalcone was synthesized in the presence of GA, using acetophenone and benzaldehyde as the reactant. The results showed that the acidity of GA was for pH = 1.12 in aqueous solution, and it was structured by the graphene sheets with the spaces between the graphene sheet and the graphene sheet and sulfuric acid (H2SO4) and acetic acid (CH3CO2H) inside the spaces. At the same time, the results also exhibited that the chalcone yield was able to reach 60.36% when GA dosage was 5 g, and the chalcone yields could attain apart 60.36, 52.05 and 31.16% when 5 g of GA was used thrice. This shows that GA is not only a high-performance catalyst, but also a controlled-release catalyst.

  9. Procedures development and methodology of control for application of good manufacture practices (GMP) on human blood irradiation

    International Nuclear Information System (INIS)

    The irradiation of human blood is used to avoid the TA-GVHD (transfusion-associated graft-versus-host-disease), a rare but devastating adverse effect of leukocytes present in blood components for a immunocompetent transfusion recipients. Usually this irradiation practice is performed to a physical elimination of leukocytes. The implementation of the procedures will assure that the properly dose in a range of 25 Gy to 50 Gy will be delivered to the blood in the bag collected in a blood tissue bank. The studies of the procedures in order to establish a GMP (Good Manufacturing Practices) were developed under the guidelines of the standard ISO 11137 - Sterilization of health care products - Requirements for validation and routine control - Radiation sterilization. In this work, two dosimetric systems were used for dose mapping during the studies of irradiator qualification, loading pattern, irradiation process validation and auditing. The CaS04:Dy dosimeter presented difficulties concerning to uncertainty on dose measurement, stability, traceability and calibration. The PMMA and Gafchromic dosimetric systems have shown a better performance and were adopted on studies of irradiators qualification that are necessary to implementation of GMP. The irradiation tests have been done in a Gammacell 220 irradiator. The developed procedures can be adapted for different kinds of gamma irradiators, allowing implanting a quality assurance program and a GMP for blood irradiation. (author)

  10. Controlling Short-Range Interactions by Tuning Surface Chemistry in HDPE/Graphene Nanoribbon Nanocomposites.

    Science.gov (United States)

    Sadeghi, Soheil; Zehtab Yazdi, Alireza; Sundararaj, Uttandaraman

    2015-09-01

    Unique dispersion states of nanoparticles in polymeric matrices have the potential to create composites with enhanced mechanical, thermal, and electrical properties. The present work aims to determine the state of dispersion from the melt-state rheological behavior of nanocomposites based on carbon nanotube and graphene nanoribbon (GNR) nanomaterials. GNRs were synthesized from nitrogen-doped carbon nanotubes via a chemical route using potassium permanganate and some second acids. High-density polyethylene (HDPE)/GNR nanocomposite samples were then prepared through a solution mixing procedure. Different nanocomposite dispersion states were achieved using different GNR synthesis methods providing different surface chemistry, interparticle interactions, and internal compartments. Prolonged relaxation of flow induced molecular orientation was observed due to the presence of both carbon nanotubes and GNRs. Based on the results of this work, due to relatively weak interactions between the polymer and the nanofillers, it is expected that short-range interactions between nanofillers play the key role in the final dispersion state. PMID:26266528

  11. Advanced methods of process/quality control in nuclear reactor fuel manufacture. Proceedings of a technical committee meeting

    International Nuclear Information System (INIS)

    Nuclear fuel plays an essential role in ensuring the competitiveness of nuclear energy and its acceptance by the public. The economic and market situation is not favorable at present for nuclear fuel designers and suppliers. The reduction in fuel prices (mainly to compete with fossil fuels) and in the number of fuel assemblies to be delivered to customers (mainly due to burnup increase) has been offset by the rising number of safety and other requirements, e.g. the choice of fuel and structural materials and the qualification of equipment. In this respect, higher burnup and thermal rates, longer fuel cycles and the use of MOX fuels are the real means to improve the economics of the nuclear fuel cycle as a whole. Therefore, utilities and fuel vendors have recently initiated new research and development programmes aimed at improving fuel quality, design and materials to produce robust and reliable fuel for safe and reliable reactor operation more demanding conditions. In this connection, improvement of fuel quality occupies an important place and this requires continuous effort on the part of fuel researchers, designers and producers. In the early years of commercial fuel fabrication, emphasis was given to advancements in quality control/quality assurance related mainly to the product itself. Now, the emphasis is transferred to improvements in process control and to implementation of overall total quality management (TQM) programmes. In the area of fuel quality control, statistical methods are now widely implemented, replacing 100% inspection. The IAEA, recognizing the importance of obtaining and maintaining high standards in fuel fabrication, has paid particular attention to this subject. In response to the rapid progress in development and implementation of advanced methods of process/quality control in nuclear fuel manufacture and on the recommendation of the International Working Group on Water Reactor Fuel Performance and Technology, the IAEA conducted a

  12. Cable manufacture

    Science.gov (United States)

    Gamble, P.

    1972-01-01

    A survey is presented of flat electrical cable manufacturing, with particular reference to patented processes. The economics of manufacture based on an analysis of material and operating costs is considered for the various methods. Attention is given to the competitive advantages of the several processes and their resulting products. The historical area of flat cable manufacture is presented to give a frame of reference for the survey.

  13. Cooperative Education. Cosmetic Science: A Career Option for Majors in Chemistry.

    Science.gov (United States)

    Lichtin, J. Leon; Radd, Billie L.

    1987-01-01

    Discusses the growing field of cosmetic science as a career option for chemistry majors. Outlines the design, formulation, manufacture, stabilization, evaluation, control management, safety, mechanism of action, and claim substantiation of cosmetic products. Provides information on the concerns and professional responsibilities of the cosmetic…

  14. REALISING THE POTENTIAL OF MANUFACTURING EXECUTION SYSTEMS

    OpenAIRE

    L. Van Dyk; C.D. Van Schoor

    2012-01-01

    ENGLISH ABSTRACT: The term Manufacturing Execution System (MES) was created by Advanced Manufacturing Research (AMR) in 1990 to describe a suite of software products, which enables the execution of manufacturing through the integration of the plann ing and control systems of an enterprise. The evolution of Manufacturing Execution Systems is a result of the evolution of manufacturing strategies, manufacturing planning and control systems , as well as the evolution of information techn...

  15. Surface chemistry

    CERN Document Server

    Desai, KR

    2008-01-01

    The surface Chemistry of a material as a whole is crucially dependent upon the Nature and type of surfaces exposed on crystallites. It is therefore vitally important to independently Study different, well - defined surfaces through surface analytical techniques. In addition to composition and structure of surface, the subject also provides information on dynamic light scattering, micro emulsions, colloid Stability control and nanostructures. The present book endeavour to bring before the reader that the understanding and exploitation of Solid state phenomena depended largely on the ability to

  16. Next Generation Advanced Binder Chemistries for High Performance, Environmentally DurableThermal Control Material Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This innovative SBIR Phase II proposal will develop next generation products for Thermal Control Material Systems (TCMS) an adhesives based on the next generation...

  17. Trajectory-Oriented and Fault-Tolerant-Based Intelligent Process Control for Flexible CIGS PV Module Manufacturing; Final Technical Report, 13 May 2002--30 May 2005

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, L.; Britt, J.; Birkmire, R.; Vincent, T.

    2005-10-01

    ITN Energy Systems, Inc., and Global Solar Energy, Inc., assisted by NREL's PV Manufacturing R&D program, have continued to advance CIGS production technology by developing trajectory-oriented predictive/control models, fault-tolerance control, control platform development, in-situ sensors, and process improvements. Modeling activities included developing physics-based and empirical models for CIGS and sputter-deposition processing, implementing model-based control, and applying predictive models to the construction of new evaporation sources and for control. Model-based control is enabled by implementing reduced or empirical models into a control platform. Reliability improvement activities include implementing preventive maintenance schedules; detecting failed sensors/equipment and reconfiguring to tinue processing; and systematic development of fault prevention and reconfiguration strategies for the full range of CIGS PV production deposition processes. In-situ sensor development activities have resulted in improved control and indicated the potential for enhanced process status monitoring and control of the deposition processes. Substantial process improvements have been made, including significant improvement in CIGS uniformity, thickness control, efficiency, yield, and throughput. In large measure, these gains have been driven by process optimization, which in turn have been enabled by control and reliability improvements due to this PV Manufacturing R&D program.

  18. Complex chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Gon; Kim, Jae Sang; Kim, Jin Eun; Lee, Boo Yeon

    2006-06-15

    This book introduces complex chemistry with ten chapters, which include development of complex chemistry on history coordination theory and Warner's coordination theory and new development of complex chemistry, nomenclature on complex with conception and define, chemical formula on coordination compound, symbol of stereochemistry, stereo structure and isomerism, electron structure and bond theory on complex, structure of complex like NMR and XAFS, balance and reaction on solution, an organo-metallic chemistry, biology inorganic chemistry, material chemistry of complex, design of complex and calculation chemistry.

  19. Complex chemistry

    International Nuclear Information System (INIS)

    This book introduces complex chemistry with ten chapters, which include development of complex chemistry on history coordination theory and Warner's coordination theory and new development of complex chemistry, nomenclature on complex with conception and define, chemical formula on coordination compound, symbol of stereochemistry, stereo structure and isomerism, electron structure and bond theory on complex, structure of complex like NMR and XAFS, balance and reaction on solution, an organo-metallic chemistry, biology inorganic chemistry, material chemistry of complex, design of complex and calculation chemistry.

  20. Ethanolic Carbon-11 Chemistry: the Introduction of Green Radiochemistry

    OpenAIRE

    Shao, Xia; Fawaz, Maria V.; Jang, Keunsam; Scott, Peter J. H.

    2014-01-01

    The principles of green chemistry have been applied to a radiochemistry setting. Eleven carbon-11 labeled radiopharmaceuticals have been prepared using ethanol as the only organic solvent throughout the entire manufacturing process. The removal of all other organic solvents from the process simplifies production and quality control (QC) testing, moving our PET Center towards the first example of a green radiochemistry laboratory. All radiopharmaceutical doses prepared are suitable for clinica...

  1. An ABWR water chemistry control design concept for low radiation exposure and the operating experience at the first ABWR

    International Nuclear Information System (INIS)

    No. 6 and 7 units of the Kashiwazaki-Kariwa Nuclear Power Station are the first advanced boiling water reactors (ABWR). Unit No. 6 (K6) started commercial operation in November 1996 and unit No. 7 (K7), which is identical to unit 6, began operation in July 1997. Both of them have now finished three cycles of operation. In the design stage of the ABWR, specifications for material selection were based on a detailed review of corrosion product mass balance from the standpoint of radiation source reduction. Improved cobalt specifications were applied to the stainless steel of the feed water heater tube and corrosion resistant steel was used in the turbine system. K6 and K7 adopted different water chemistry controls to reduce the dose rate during plant operation. K6 used extremely low iron crud control in the feed water and K7 used improved Ni/Fe control. As the result of these challenges, both of them attained the design target of less than 0.36 mSv/year radiation exposure. (authors)

  2. A comparison of inventory control policies for a joint manufacturing/Remanufacturing environment with remanufacturing yield loss

    OpenAIRE

    Bayindir, Pelin; Teunter, Ruud; Dekker, Rommert

    2005-01-01

    textabstractWe consider a joint manufacturing / remanufacturing environment with remanufacturing yield loss. Demand and return follow independent stationary Poisson processes. Returns can be disposed off upon arrival to the system. Manufacturing and remanufacturing operations performed in the same facility at exponential rates. Yield information becomes available after remanufacturing. Demands that are not directly satisfied are lost. We investigate what inventories to consider when making pr...

  3. Mathematical Chemistry

    OpenAIRE

    Trinajstić, Nenad; Gutman, Ivan

    2002-01-01

    A brief description is given of the historical development of mathematics and chemistry. A path leading to the meeting of these two sciences is described. An attempt is made to define mathematical chemistry, and journals containing the term mathematical chemistry in their titles are noted. In conclusion, the statement is made that although chemistry is an experimental science aimed at preparing new compounds and materials, mathematics is very useful in chemistry, among other things, to produc...

  4. Manufacturing technologies

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    The Manufacturing Technologies Center is an integral part of Sandia National Laboratories, a multiprogram engineering and science laboratory, operated for the Department of Energy (DOE) with major facilities at Albuquerque, New Mexico, and Livermore, California. Our Center is at the core of Sandia`s Advanced Manufacturing effort which spans the entire product realization process.

  5. Immunity induced by a broad class of inorganic crystalline materials is directly controlled by their chemistry

    NARCIS (Netherlands)

    G.R. Williams (Gareth); K. Fierens (Kaat); S.G. Preston (Stephen); A.C. Lunn; O. Rysnik (Oliwia); S. de Prijck (Sofie); M. Kool (Mirjam); H.C. Buckley (Hannah); B.N.M. Lambrecht (Bart); D. O'Hare (Dermot); J.M. Austyn (Jonathan)

    2014-01-01

    textabstractThere is currently no paradigm in immunology that enables an accurate prediction of how the immune system will respond to any given agent. Here we show that the immunological responses induced by members of a broad class of inorganic crystalline materials are controlled purely by their p

  6. DOE fundamentals handbook: Chemistry

    International Nuclear Information System (INIS)

    This handbook was developed to assist nuclear facility operating contractors in providing operators, maintenance personnel, and the technical staff with the necessary fundamentals training to ensure a basic understanding of chemistry. This volume contains the following modules: reactor water chemistry (effects of radiation on water chemistry, chemistry parameters), principles of water treatment (purpose; treatment processes [ion exchange]; dissolved gases, suspended solids, and pH control; water purity), and hazards of chemicals and gases (corrosives [acids, alkalies], toxic compounds, compressed gases, flammable/combustible liquids)

  7. Chemistry in Microfluidic Channels

    Science.gov (United States)

    Chia, Matthew C.; Sweeney, Christina M.; Odom, Teri W.

    2011-01-01

    General chemistry introduces principles such as acid-base chemistry, mixing, and precipitation that are usually demonstrated in bulk solutions. In this laboratory experiment, we describe how chemical reactions can be performed in a microfluidic channel to show advanced concepts such as laminar fluid flow and controlled precipitation. Three sets of…

  8. Geogenic control on soil chemistry in urban areas : a novel method for urban geochemical mapping using parent material classified data

    OpenAIRE

    Appleton, J.D.; Adlam, K.A.M.

    2012-01-01

    The purpose of the study reported here is to assess whether it may in some circumstances be useful and appropriate to use a parent material (PM) soil chemistry mapping method developed for national soil chemistry data to portray spatial variation in urban soil chemistry data in Great Britain. Analysis of variance (ANOVA) of the urban soil data suggests that spatial interpolation of soil ambient background concentrations (ABCs) using PM classified soil data may be justified for those elements ...

  9. Experiences on IGSCC crack manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Veron, P. [Equipos Nucleares, S.A., Maliano (Spain)

    1997-02-01

    The author presents his experience in manufacturing IGSCC realistic defects, mainly in INCONEL 600 MA Steam Generator Tubes. From that experience he extracts some knowledge about this cracking (influence of chemistry in the environment, stress state, crack growth rate, and occurrence in laboratory condition of break before leak).

  10. Improved Recovery Boiler Performance Through Control of Combustion, Sulfur, and Alkali Chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Baxter, Larry L.

    2008-06-09

    This project involved the following objectives: 1. Determine black liquor drying and devolatilization elemental and total mass release rates and yields. 2. Develop a public domain physical/chemical kinetic model of black liquor drop combustion, including new information on drying and devolatilization. 3. Determine mechanisms and rates of sulfur scavenging in recover boilers. 4. Develop non-ideal, public-domain thermochemistry models for alkali salts appropriate for recovery boilers 5. Develop data and a one-dimensional model of a char bed in a recovery boiler. 6. Implement all of the above in comprehensive combustion code and validate effects on boiler performance. 7. Perform gasification modeling in support of INEL and commercial customers. The major accomplishments of this project corresponding to these objectives are as follows: 1. Original data for black liquor and biomass data demonstrate dependencies of particle reactions on particle size, liquor type, gas temperature, and gas composition. A comprehensive particle submodel and corresponding data developed during this project predicts particle drying (including both free and chemisorbed moisture), devolatilization, heterogeneous char oxidation, char-smelt reactions, and smelt oxidation. Data and model predictions agree, without adjustment of parameters, within their respective errors. The work performed under these tasks substantially exceeded the original objectives. 2. A separate model for sulfur scavenging and fume formation in a recovery boiler demonstrated strong dependence on both in-boiler mixing and chemistry. In particular, accurate fume particle size predictions, as determined from both laboratory and field measurements, depend on gas mixing effects in the boilers that lead to substantial particle agglomeration. Sulfur scavenging was quantitatively predicted while particle size required one empirical mixing factor to match data. 3. Condensed-phase thermochemistry algorithms were developed for salt

  11. Development of chemistry support programme for algae control in spray pond waters of CIRUS reactor

    International Nuclear Information System (INIS)

    A major problem in any open recirculating cooling water system, is the growth of micro-organisms, especially algae, which adversely affects the efficient and safe operation of the plant. The algae control depends to a great extent, on the selection of an effective algaecide and on the adoption of proper dose and dosing frequency of the algaecide. The present paper describes the development of (i) a generally applicable analytical method for comparing the algicidal efficacies of available commercial algaecides, for the specific local strains of algae in the spray pond waters of CIRUS reactor at Trombay, and (ii) a procedure for assessing 'algicide demand' in open recirculating cooling water systems, which can be used to establish an effective and efficient algae control programme. (author)

  12. The Incorporation of Single Crystal X-Ray Diffraction into the Undergraduate Chemistry Curriculum Using Internet-Facilitated Remote Diffractometer Control

    Science.gov (United States)

    Szalay, P. S.; Hunter, A. D.; Zeller, M.

    2005-01-01

    The benefits of integrating single crystal X-ray diffraction into the curricula of the disciplines of science such as chemistry, biology, biochemistry physics, and many more are addressed. The results showed that students were able to complete all report requirements with the aid of handouts and instructor inputs, and remote control of the…

  13. Development of valence-directed nanoparticle building blocks on the basis of controlled bio/nano-interfacing chemistry

    Science.gov (United States)

    Kim, Jeong-Hwan

    The assembly of nanoparticles in controllable and predictable ways would not only aid practical nanoscale assembly, which requires accurate and scalable assembly of large and complex nanoscale structures, but also would increase their utility for many applications, including electronics, optics, sensing and imaging, medical diagnostics, etc. Well-defined and controlled functionality and directionality of the building blocks are essential to actively control the molecular assembly processes at the nanometer scale. Such controls over the functionality and directionality would enable us to construct sophisticated nanostructures to take advantage of the increasing number of available nanocomponents and ultimately to approximate the complexity and the functionality of current microfabrication. We have developed a serial solid-phase placement approach to synthesize anisotropically or symmetrically functionalized gold nanoparticles (AuNPs), in which the functionality and directionality (e.g., numbers, locations, and orientations) of the functional ligands are controlled. Two types of bi-functionalized (bif-) AuNPs were synthesized at a site-specific manner with increased yield and accuracy: (1) homo-bif-AuNPs with two carboxyl groups at ˜180° angle (para-configuration) and (2) hetero-bif-AuNPs with one carboxyl and one amine functional groups at less than 180°, but greater than 90° angle (meta-configuration). With such control, we successfully demonstrated the assembly of intentionally designed one-dimensional (1D) chains with homo-bif-AuNPs and two-dimensional (2D) rings with hetero-bif-AuNPs, confirming the high functional as well as directional selectivity of the functionalized NPs. This study represents an important step towards accurate, reliable, and scaled-up manufacturing of complex nanoscale structures, potentially making 'bottom-up' nanofabrication of practical use. We have further developed the ligand replacement technology to achieve such active controls

  14. Rapid small lot manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Harrigan, R.W.

    1998-05-09

    The direct connection of information, captured in forms such as CAD databases, to the factory floor is enabling a revolution in manufacturing. Rapid response to very dynamic market conditions is becoming the norm rather than the exception. In order to provide economical rapid fabrication of small numbers of variable products, one must design with manufacturing constraints in mind. In addition, flexible manufacturing systems must be programmed automatically to reduce the time for product change over in the factory and eliminate human errors. Sensor based machine control is needed to adapt idealized, model based machine programs to uncontrolled variables such as the condition of raw materials and fabrication tolerances.

  15. Gold nanoparticle growth control - Implementing novel wet chemistry method on silicon substrate

    KAUST Repository

    Al-Ameer, Ammar

    2013-04-01

    Controlling particle size, shape, nucleation, and self-assembly on surfaces are some of the main challenges facing electronic device fabrication. In this work, growth of gold nanoparticles over a wide range of sizes was investigated by using a novel wet chemical method, where potassium iodide is used as the reducing solution and gold chloride as the metal precursor, on silicon substrates. Four parameters were studied: soaking time, solution temperature, concentration of the solution of gold chloride, and surface pre-treatment of the substrate. Synthesized nanoparticles were then characterized using scanning electron microscopy (SEM). The precise control of the location and order of the grown gold overlayer was achieved by using focused ion beam (FIB) patterning of a silicon surface, pre-treated with potassium iodide. By varying the soaking time and temperature, different particle sizes and shapes were obtained. Flat geometrical shapes and spherical shapes were observed. We believe, that the method described in this work is potentially a straightforward and efficient way to fabricate gold contacts for microelectronics. © 2013 IEEE.

  16. Revenue Management in Make-To-Order Manufacturing: Case Study of Capacity Control at ThyssenKrupp VDM

    Directory of Open Access Journals (Sweden)

    André Hintsches

    2010-10-01

    Full Text Available While revenue management (RM is traditionally considered a tool of service operations, RM shows considerable potential for application in manufacturing operations. The typical challenges in make-to-order manufacturing are fixed manufacturing capacities and a great variety in offered products, going along with pronounced fluctuations in demand and profitability. Since Harris and Pinder in the mid-90s, numerous papers have furthered the understanding of RM theory in this environment. Nevertheless, results to be expected from applying the developed methods to a practical industry setting have yet to be reported. To this end, this paper investigates a possible application of RM at ThyssenKrupp VDM, leading to considerable improvements in several areas.

  17. Back-to-back 'one-pot' [18F]FDG syntheses in a single Siemens-CTI chemistry process control unit

    International Nuclear Information System (INIS)

    Simple changes in the chemistry, plumbing, and programming of the Siemens-CTI chemistry process control unit (CPCU) effectively double its output by enabling two back-to-back '1-pot' syntheses of 2-[18F]fluoro-2-deoxy-D-glucose in a single unit. Replacement of Kryptofix 2.2.2 with tetramethylammonium carbonate and elimination of diethyl ether from the procedure shorten synthesis time to 48 min, improve process and end-product safety, and increase end-of-synthesis yields from 37% to 52% by minimizing steps and transfer losses

  18. Application of a B ampersand W developed computer aided pictorial process planning system to CQMS for manufacturing process control

    International Nuclear Information System (INIS)

    Babcock ampersand Wilcox (B ampersand W) will utilize its internally developed Computer Aided Pictorial Process Planning or CAPPP (pronounced open-quotes cap cubedclose quotes) system to create a paperless manufacturing environment for the Collider Quadruple Magnets (CQM). The CAPPP system consists of networked personal computer hardware and software used to: (1) generate and maintain the documents necessary for product fabrication, (2) communicate the information contained in these documents to the production floor, and (3) obtain quality assurance and manufacturing feedback information from the production floor. The purpose of this paper is to describe the various components of the CAPPP system and explain their applicability to product fabrication, specifically quality assurance functions

  19. Sonogashira cross-coupling under non-basic conditions. Flow chemistry as a new paradigm in reaction control

    Czech Academy of Sciences Publication Activity Database

    Voltrová, Svatava; Šrogl, Jiří

    2014-01-01

    Roč. 1, č. 9 (2014), s. 1067-1071. ISSN 2052-4129 R&D Projects: GA MŠk LH12013 Institutional support: RVO:61388963 Keywords : Sonogashira * cross-coupling * flow chemistry Subject RIV: CC - Organic Chemistry

  20. Controllable optical emission spectroscopy diagnostic system for analysis of process chemistries

    International Nuclear Information System (INIS)

    Optical emission spectroscopy (OES) diagnostics have been employed for many years in plasma etch end point detection schemes. Unfortunately some newer process systems have much lower optical emission or limited optical access. To overcome such limitations, an OES diagnostic system making use of variable e-beam has been developed. That system is described and initial experimental results are presented. A strong correlation is observed between the optical emission intensity and e-beam current, a measurable electrical parameter. This correlation offers means to normalize optical signal and to be used as a feedback input to the electronics that control the plasma source. In addition there is a measurable response from the different lines due to energy of the electrons, indicating a new degree of freedom in the diagnostic that can be tapped for more precise analysis of end point.

  1. Smart Manufacturing.

    Science.gov (United States)

    Davis, Jim; Edgar, Thomas; Graybill, Robert; Korambath, Prakashan; Schott, Brian; Swink, Denise; Wang, Jianwu; Wetzel, Jim

    2015-01-01

    Historic manufacturing enterprises based on vertically optimized companies, practices, market share, and competitiveness are giving way to enterprises that are responsive across an entire value chain to demand dynamic markets and customized product value adds; increased expectations for environmental sustainability, reduced energy usage, and zero incidents; and faster technology and product adoption. Agile innovation and manufacturing combined with radically increased productivity become engines for competitiveness and reinvestment, not simply for decreased cost. A focus on agility, productivity, energy, and environmental sustainability produces opportunities that are far beyond reducing market volatility. Agility directly impacts innovation, time-to-market, and faster, broader exploration of the trade space. These changes, the forces driving them, and new network-based information technologies offering unprecedented insights and analysis are motivating the advent of smart manufacturing and new information technology infrastructure for manufacturing. PMID:25898070

  2. Micro Manufacturing

    DEFF Research Database (Denmark)

    Hansen, Hans Nørgaard

    2003-01-01

    micro manufacturing system isn’t designed rationally and correctly, it will be high-cost, unreliable, and not robust. For micro products and systems it is a continuously increasing challenge to create the operational basis for an industrial production. As the products through product development......Manufacturing deals with systems that include products, processes, materials and production systems. These systems have functional requirements, constraints, design parameters and process variables. They must be decomposed in a systematic manner to achieve the best possible system performance. If a...... processes are made applicable to a large number of customers, the pressure in regard to developing production technologies that make it possible to produce the products at a reasonable price and in large numbers is growing. The micro/nano manufacturing programme at the Department of Manufacturing...

  3. Papyrus Manufacture

    OpenAIRE

    Leach, Bridget

    2009-01-01

    The papyrus plant that grew along the River Nile was used to manufacture writing material in ancient Egypt. It was employed throughout the Classical Period and beyond until superseded by paper in about 800 CE.

  4. A Contingency Theory-based Investigation of the Role of Management Accounting Information in Management Control Systems in Large Manufacturing Companies in Libya

    OpenAIRE

    Haedr, Adel Ramdan

    2012-01-01

    In an attempt to provide a better understanding of the design and use of effective management control systems (MCS) in a developing country, this research study adopts a contingency theory approach to investigate the role of management accounting information (MAI) in facilitating MCS in large manufacturing companies. Drawing the relevant literature on contingency theory, a framework is developed and forms the basis for investigating the possible influence of several contingent variables, inc...

  5. Influence of wall thickness of spheroidal cast iron, manufactured in the foundry METAL-ODLEW Sp.J., on its graphite shape index and ultrasonic control index

    Directory of Open Access Journals (Sweden)

    W. Orłowicz

    2009-07-01

    Full Text Available This work presents the results of ultrasonic evaluation of the microstructure of spheroidal cast iron manufactured under production condi-tions at the foundry of Metal Odlew Sp.J. Evaluation of ultrasonic control index sensitiveness to changes of graphite shape index Ss of spheroidal cast iron (type 500-7, utilized modelled stepped castings. The relationship was determined between the shape index of graphite precipitation Ss and the velocity of longitudinal ultrasonic wave cL.

  6. Influence of wall thickness of spheroidal cast iron, manufactured in the foundry METAL-ODLEW Sp.J., on its graphite shape index and ultrasonic control index

    OpenAIRE

    W. Orłowicz; M. Tupaj; M. Mróz; E. Guzik; J. Nykiel; A. Zając; B. Piotrowski

    2009-01-01

    This work presents the results of ultrasonic evaluation of the microstructure of spheroidal cast iron manufactured under production condi-tions at the foundry of Metal Odlew Sp.J. Evaluation of ultrasonic control index sensitiveness to changes of graphite shape index Ss of spheroidal cast iron (type 500-7), utilized modelled stepped castings. The relationship was determined between the shape index of graphite precipitation Ss and the velocity of longitudinal ultrasonic wave cL.

  7. Looking at the future of manufacturing metrology: roadmap document of the German VDI/VDE Society for Measurement and Automatic Control

    OpenAIRE

    J. Berthold; Imkamp, D.

    2013-01-01

    "Faster, safer, more accurately and more flexibly'' is the title of the "manufacturing metrology roadmap'' issued by the VDI/VDE Society for Measurement and Automatic Control (http://www.vdi.de/gma). The document presents a view of the development of metrology for industrial production over the next ten years and was drawn up by a German group of experts from research and industry. The following paper summarizes the content of the roadmap and explains the individual concepts of "Faster, safer...

  8. Combinatorial chemistry

    DEFF Research Database (Denmark)

    Nielsen, John

    1994-01-01

    An overview of combinatorial chemistry is presented. Combinatorial chemistry, sometimes referred to as `irrational drug design,' involves the generation of molecular diversity. The resulting chemical library is then screened for biologically active compounds.......An overview of combinatorial chemistry is presented. Combinatorial chemistry, sometimes referred to as `irrational drug design,' involves the generation of molecular diversity. The resulting chemical library is then screened for biologically active compounds....

  9. Positronium chemistry

    CERN Document Server

    Green, James

    1964-01-01

    Positronium Chemistry focuses on the methodologies, reactions, processes, and transformations involved in positronium chemistry. The publication first offers information on positrons and positronium and experimental methods, including mesonic atoms, angular correlation measurements, annihilation spectra, and statistical errors in delayed coincidence measurements. The text then ponders on positrons in gases and solids. The manuscript takes a look at the theoretical chemistry of positronium and positronium chemistry in gases. Topics include quenching, annihilation spectrum, delayed coincidence

  10. 78 FR 11611 - Current Good Manufacturing Practice and Hazard Analysis and Risk-Based Preventive Controls for...

    Science.gov (United States)

    2013-02-19

    ..., 2013 (78 FR 3646), is extended. Submit either electronic or written comments by May 16, 2013. ADDRESSES... INFORMATION: I. Background In the Federal Register of January 16, 2013 (78 FR 3646), FDA published a proposed..., and 211 RIN 0910-AG36 Current Good Manufacturing Practice and Hazard Analysis and Risk-...

  11. Costing support and cost control in manufacturing. A cost estimation tool applied in the sheet metal domain.

    NARCIS (Netherlands)

    Brinke, ten Erik

    2002-01-01

    In the product development cycle several engineering tasks like design, process planning and production planning have to be executed. The execution of these tasks mainly involves information processing and decision-making. Because costs is an important factor in manufacturing, adequate information a

  12. Linking management accounting and control systems, strategy, information technology, manufacturing technology and organizational performance of the firm in contingency framework

    OpenAIRE

    Hyvönen, J. (Johanna)

    2008-01-01

    Abstract This dissertation aims to provide an extensive picture of management accounting systems and explore the relationships between management accounting systems, strategy, information technology, manufacturing technology and organizational performance. The dissertation consists of four essays. The first essay focuses on the adoption and benefits of management accounting practices, whereas the second essay studies the relations between customer-focused strategy, performance measurement ...

  13. Pulmonary toxicity of manufactured nanoparticles

    Science.gov (United States)

    Peebles, Brian Christopher

    that carbon blacks contain free radical and other surface functionality as manufactured, and that exposure to ozone further functionalizes the surface. Samples of carbon black that have been exposed to ozone react with their ambient environment so that acid anhydride and cyclic ether functionality hydrolyze to form carboxylic acid functionality, observable by transmission Fourier transform infrared spectroscopy. Persistent free radical content, but not free radical content from ozone exposure, may mediate the toxic response of cells to carbon blacks in vitro. Results showed that macrophages exposed to carbon blacks that had been exposed to ozone were not less viable in vitro than macrophages exposed to carbon blacks as manufactured because the free radical content that resulted from ozone exposure was not persistent in an aqueous medium. Furthermore, concurrent exposure to ozonated carbon blacks and ozone was less lethal to macrophages than carbon black exposure alone, possibly because the ozone oxidatively preconditioned the macrophages to resist oxidative stress. The nature of redox-active iron species on the surface of iron-loaded synthetic carbon particles was explored. The particles had been shown in previous studies to provoke an inflammatory response involving the release of tumor necrosis factor (TNF)-alpha, which was correlated with their production of hydroxyl free radicals via the Fenton reaction in the presence of hydrogen peroxide. It was found that the source of bioavailable Fenton-active iron on the surfaces of the particles was fluoride species that were byproducts of a step in the synthetic process. Fluoride ligated the iron already on the surface, forming a complex that resisted precipitation in the biological medium and thus made the iron more bioavailable. The results of this thesis aim to clarify whether the size and surface chemistry of nanoparticles should be considered more closely as criteria with which to develop better environmental controls

  14. Application of photochemical indicators to evaluate ozone nonlinear chemistry and pollution control countermeasure in China

    Science.gov (United States)

    Xie, Min; Zhu, Kuanguang; Wang, Tijian; Yang, Haoming; Zhuang, Bingliang; Li, Shu; Li, Minggao; Zhu, Xinsheng; Ouyang, Yan

    2014-12-01

    Ozone sensitivity in China was investigated by using a comprehensive three-dimensional air quality model system WRF-CALGRID. A real case and two cases with 35% emission reduction for either NOx or VOC were conducted for the period of March in 2010. The simulation results of O3 agreed fairly well with the observation data. Based on the meaning of O3 sensitivity, the ratio Ra was defined, with the transition value of 1 to distinguish NOx-sensitive region from VOC-sensitive region. With the aid of Ra, VOC- and NOx-sensitive regions in China were preliminary located. The transition ranges for some photochemical indicators were quantified. Only those of H2O2/NOz and H2O2/HNO3 met the requirement that the 95th percentile VOC-sensitive value should be equal to or lower than the 5th percentile NOx-sensitive value. 0.16-0.40 for H2O2/HNO3 and 0.14-0.28 for H2O2/NOz were adopted to distinguish different O3 sensitivity in China. The results showed that the VOC-sensitive regions are primarily distributed over the urban centers and the developed industrial areas in eastern and southern China, while the NOx-sensitive regions are mainly located in the remote areas of northern and western China. High correlation between Ra and indicators was found, and a new approach to quantify the transition values of indicators was proposed. These indicators can play an important role in the air complex pollution control of urban clusters over East Asia.

  15. Demonstration of thermal control, microstructure control, defect mitigation and process parameter database generation for Ti-6Al-4V Direct Digital Manufacturing - Understanding defect mitigation and process parameter database generation for direct digital manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    Dehoff, Ryan R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sridharan, Niyanth [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dinwiddie, Ralph [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Robson, Alan [Univ. of Tennessee, Knoxville, TN (United States); Jordan, Brian [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Chaudhary, Anil [Applied Optimization, Dayton, OH (United States); Babu, Sudarsanam Suresh [Univ. of Tennessee, Knoxville, TN (United States)

    2015-09-01

    Researchers from Manufacturing Demonstration Facility (MDF) at Oak Ridge National Laboratory (ORNL) worked with Applied Optimization (AO) to understand and evaluate the propensity for defect formation in builds manufactured using DM3D-POM laser direct metal deposition. The main aim of this collaboration was to understand the character of powder jet behavior as a function of the nozzle parameters such as cover gas, carrier gas, and shaping gas. In order to evaluate the sensitivities of the parameters used in model, various experiments were performed with in-situ monitoring of the powder stream characteristics using a high speed camera. A wide variety of conditions while keeping the hopper motor rpm constant, including laser power and travel speed were explored. The cross sections of the deposits were characterized using optical microscopy.

  16. On the Green's function of the partially diffusion-controlled reversible ABCD reaction for radiation chemistry codes

    Energy Technology Data Exchange (ETDEWEB)

    Plante, Ianik, E-mail: ianik.plante-1@nasa.gov [Wyle Science, Technology & Engineering, 1290 Hercules, Houston, TX 77058 (United States); Devroye, Luc, E-mail: lucdevroye@gmail.com [School of Computer Science, McGill University, 3480 University Street, Montreal H3A 0E9 (Canada)

    2015-09-15

    Several computer codes simulating chemical reactions in particles systems are based on the Green's functions of the diffusion equation (GFDE). Indeed, many types of chemical systems have been simulated using the exact GFDE, which has also become the gold standard for validating other theoretical models. In this work, a simulation algorithm is presented to sample the interparticle distance for partially diffusion-controlled reversible ABCD reaction. This algorithm is considered exact for 2-particles systems, is faster than conventional look-up tables and uses only a few kilobytes of memory. The simulation results obtained with this method are compared with those obtained with the independent reaction times (IRT) method. This work is part of our effort in developing models to understand the role of chemical reactions in the radiation effects on cells and tissues and may eventually be included in event-based models of space radiation risks. However, as many reactions are of this type in biological systems, this algorithm might play a pivotal role in future simulation programs not only in radiation chemistry, but also in the simulation of biochemical networks in time and space as well.

  17. On the Green's function of the partially diffusion-controlled reversible ABCD reaction for radiation chemistry codes

    International Nuclear Information System (INIS)

    Several computer codes simulating chemical reactions in particles systems are based on the Green's functions of the diffusion equation (GFDE). Indeed, many types of chemical systems have been simulated using the exact GFDE, which has also become the gold standard for validating other theoretical models. In this work, a simulation algorithm is presented to sample the interparticle distance for partially diffusion-controlled reversible ABCD reaction. This algorithm is considered exact for 2-particles systems, is faster than conventional look-up tables and uses only a few kilobytes of memory. The simulation results obtained with this method are compared with those obtained with the independent reaction times (IRT) method. This work is part of our effort in developing models to understand the role of chemical reactions in the radiation effects on cells and tissues and may eventually be included in event-based models of space radiation risks. However, as many reactions are of this type in biological systems, this algorithm might play a pivotal role in future simulation programs not only in radiation chemistry, but also in the simulation of biochemical networks in time and space as well

  18. On the Green's function of the partially diffusion-controlled reversible ABCD reaction for radiation chemistry codes

    Science.gov (United States)

    Plante, Ianik; Devroye, Luc

    2015-09-01

    Several computer codes simulating chemical reactions in particles systems are based on the Green's functions of the diffusion equation (GFDE). Indeed, many types of chemical systems have been simulated using the exact GFDE, which has also become the gold standard for validating other theoretical models. In this work, a simulation algorithm is presented to sample the interparticle distance for partially diffusion-controlled reversible ABCD reaction. This algorithm is considered exact for 2-particles systems, is faster than conventional look-up tables and uses only a few kilobytes of memory. The simulation results obtained with this method are compared with those obtained with the independent reaction times (IRT) method. This work is part of our effort in developing models to understand the role of chemical reactions in the radiation effects on cells and tissues and may eventually be included in event-based models of space radiation risks. However, as many reactions are of this type in biological systems, this algorithm might play a pivotal role in future simulation programs not only in radiation chemistry, but also in the simulation of biochemical networks in time and space as well.

  19. Beyond interfacial anion/cation pairing: The role of Cu(I) coordination chemistry in additive-controlled copper plating

    International Nuclear Information System (INIS)

    Highlights: ► We study synergistic and antagonistic ensemble effects of various polymeric suppressor additives and MPS relevant for copper electroplating. ► Type-I suppressors (e.g. PEGs) show a purely antagonistic interaction with MPS. ► Type-II suppressors (e.g. PEIs) show a purely synergistic interaction with MPS. ► Hybrid suppressors (e.g. Imep) reveal both synergistic and antagonistic effects depending on the MPS concentration. ► We identify a combination of Cu(I) coordination chemistry and an inner salt formation as key to the understanding of the suppressing mode of polymeric leveler additives. - Abstract: This study reinvestigates the electrochemical characteristics of three different suppressor additives that are used in context of industrial copper plating (Damascene, Through-Silicon-Via). It is the particular aim of this contribution to further substantiate our recently introduced classification scheme of suppressor chemistries that relies on their antagonistic and synergistic interplay with MPS (mercaptopropane sulfonic acid/sulfonate). The latter appears as intermediate species in the course of copper electrodeposition in the presence of SPS (bis-(sodium-sulfopropyl)-disulfide). Both the linear sweep voltammetry and potential transient experiments reveal a purely antagonistic interaction between PAG (polyalkylene glycol) based suppressor ensembles and the SPS (MPS precursor) which is rationalized in terms of the coordinative dissolution of a hyper-branched PAG-Cu(I)-Cl coordination network by the MPS. Such purely antagonistic suppressor/MPS interplay is our criterion for a so-called type-I suppressor. A purely synergistic suppressor/MPS interaction is observed for the PEI (polyethylene-imine) which can be considered as a prototypical type-II suppressor. Beyond classical interfacial anion/cation pairing the partly protonated, poly-cationic PEI is capable to form MPS-stabilized Cu(I) adducts. Their suppressing effect relies on an in situ hyper

  20. Chemistry in water reactors

    International Nuclear Information System (INIS)

    The international conference Chemistry in Water Reactors was arranged in Nice 24-27/04/1994 by the French Nuclear Energy Society. Examples of technical program areas were primary chemistry, operational experience, fundamental studies and new technology. Furthermore there were sessions about radiation field build-up, hydrogen chemistry, electro-chemistry, condensate polishing, decontamination and chemical cleaning. The conference gave the impression that there are some areas that are going to be more important than others during the next few years to come. Cladding integrity: Professor Ishigure from Japan emphasized that cladding integrity is a subject of great concern, especially with respect to waterside corrosion, deposition and release of crud. Chemistry control: The control of the iron/nickel concentration quotient seems to be not as important as previously considered. The future operation of a nuclear power plant is going to require a better control of the water chemistry than achievable today. One example of this is solubility control via regulation in BWR. Trends in USA: means an increasing use of hydrogen, minimization of SCC/IASCC, minimization of radiation fields by thorough chemistry control, guarding fuel integrity by minimization of cladding corrosion and minimization of flow assisted corrosion. Stellite replacement: The search for replacement materials will continue. Secondary side crevice chemistry: Modeling and practical studies are required to increase knowledge about the crevice chemistry and how it develops under plant operation conditions. Inhibitors: Inhibitors for IGSCC and IGA as well for the primary- (zinc) as for the secondary side (Ti) should be studied. The effects and mode of operation of the inhibitors should be documented. Chemical cleaning: of heat transfer surfaces will be an important subject. Prophylactic cleaning at regular intervals could be one mode of operation

  1. Catalysis as a foundational pillar of green chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Anastas, Paul T. [White House Office of Science and Technology Policy, Department of Chemistry, University of Nottingham Nottingham, (United Kingdom); Kirchhoff, Mary M. [U.S. Environmental Protection Agency and Trinity College, Washington, DC (United States); Williamson, Tracy C. [U.S. Environmental Protection Agency, Washington, DC (United States)

    2001-11-30

    Catalysis is one of the fundamental pillars of green chemistry, the design of chemical products and processes that reduce or eliminate the use and generation of hazardous substances. The design and application of new catalysts and catalytic systems are simultaneously achieving the dual goals of environmental protection and economic benefit. Green chemistry, the design of chemical products and processes that reduce or eliminate the use and generation of hazardous substances, is an overarching approach that is applicable to all aspects of chemistry. From feedstocks to solvents, to synthesis and processing, green chemistry actively seeks ways to produce materials in a way that is more benign to human health and the environment. The current emphasis on green chemistry reflects a shift away from the historic 'command-and-control' approach to environmental problems that mandated waste treatment and control and clean up through regulation, and toward preventing pollution at its source. Rather than accepting waste generation and disposal as unavoidable, green chemistry seeks new technologies that are cleaner and economically competitive. Utilizing green chemistry for pollution prevention demonstrates the power and beauty of chemistry: through careful design, society can enjoy the products on which we depend while benefiting the environment. The economic benefits of green chemistry are central drivers in its advancement. Industry is adopting green chemistry methodologies because they improve the corporate bottom line. A wide array of operating costs are decreased through the use of green chemistry. When less waste is generated, environmental compliance costs go down. Treatment and disposal become unnecessary when waste is eliminated. Decreased solvent usage and fewer processing steps lessen the material and energy costs of manufacturing and increase material efficiency. The environmental, human health, and the economic advantages realized through green chemistry

  2. Chain Sprockets Manufacturing, on Vertical Machining Center GDV400PM1F4 Updated with Numerical Control NCT®2000M

    Directory of Open Access Journals (Sweden)

    Ioan Francisc Fekete

    2013-06-01

    Full Text Available The paper content comprise a few aspects regarding processing of chain sprockets on vertical processing center GDV400PM1F4 updated by changing the original equipment CNC-2S42-65 (1Я3.035.090 with NCT®2000M, which includes in short characteristics of two CNC, the old and the new one, the constructive elements of chain sprockets processed, enunciation of mains stages of manufacturing process adopted. The aim is to manufacture chain sprockets with classic tools, bypassing the need to design and build a sprocket hob in accordance with specified chain sprockets geometry, processing is performed on a machine which technological parameters have been improved.

  3. Simulation Model Driven Engineering for Manufacturing Cell

    OpenAIRE

    Hibino, Hironori; Inukai, Toshihiro; Yoshida, Yukishige

    2010-01-01

    In our research, the simulation model driven engineering for manufacturing cell (SMDE-MC) is proposed. The purposes of SMDE-MC are to support the manufacturing engineering processes based on the simulation model and to extend the range of control applications and simulation applications using the PC based control. SMDE-MC provides the simulation model which controls and monitors the manufacturing cell directly using PC based control in the manufacturing system execution phase. Then when the s...

  4. New pH-tunable vlock copolymer nanoparticles via controlled radical polymerization and azide-bintrile click chemistry

    Czech Academy of Sciences Publication Activity Database

    Jäger, Alessandro; Gromadzki, Daniel; Štěpánek, Petr

    Praha : Institute of Macromolecular Chemistry , 2009. s. 74. ISBN 978-80-85009-59-0. [Prague Meetings on Macromolecules /73./ New Frontiers in Macromolecular Science: From Macromolecular Concepts of Living Matter to Polymers for Better Quality of Life. 05.07.2009-09.07.2009, Prague] R&D Projects: GA ČR GA202/09/2078 Institutional research plan: CEZ:AV0Z40500505 Keywords : photoelectrical properties * solar energy Subject RIV: CD - Macromolecular Chemistry

  5. Manufacture of first wall mock-ups with calibrated defects for fabrication control methods: Development of UT detectable defects

    International Nuclear Information System (INIS)

    A Research and Development program for the ITER Blanket-First Wall has been implemented in Europe to provide input data for the manufacture of the full-scale production components. In this frame, FW mock-ups have been fabricated according to ITER FW design requirements. In order to define acceptance criteria for non-destructive examination (NDE) for the series production, FW mock-ups (FWMU) representative of ITER FW are manufactured with calibrated defects to be validated by heat flux tests to assess the critical defect dimensions able to degrade fatigue performance and lifetime, when located at Be/CuCrZr joint corners and beryllium tile edges, and at the CuCrZr/CuCrZr and CuCrZr/316L SS joints. In order to create the defects of given dimensions, two techniques were studied: alumina and zirconia coating using a PVD technique in one hand; and on the another hand alumina and quartz thicker inserts. The paper describes the different approaches used to manufacture test samples with calibrated defects, before applying on FW mock-ups, and related non-destructive examination (NDE) by ultrasonic examination (UT). High heat flux (HHF) testing is not part of this work.

  6. Graduate Education in Environmental Chemistry

    Science.gov (United States)

    Lee, G. Fred

    1974-01-01

    Describes the role chemistry departments should assume in the environmental quality control area. Includes problems of program design, course offerings, research problems, and career qualifications. (GS)

  7. Human Development VIII: A Theory of “Deep” Quantum Chemistry and Cell Consciousness: Quantum Chemistry Controls Genes and Biochemistry to Give Cells and Higher Organisms Consciousness and Complex Behavior

    Directory of Open Access Journals (Sweden)

    Søren Ventegodt

    2006-01-01

    Full Text Available Deep quantum chemistry is a theory of deeply structured quantum fields carrying the biological information of the cell, making it able to remember, intend, represent the inner and outer world for comparison, understand what it “sees”, and make choices on its structure, form, behavior and division. We suggest that deep quantum chemistry gives the cell consciousness and all the qualities and abilities related to consciousness. We use geometric symbolism, which is a pre-mathematical and philosophical approach to problems that cannot yet be handled mathematically. Using Occam’s razor we have started with the simplest model that works; we presume this to be a many-dimensional, spiral fractal. We suggest that all the electrons of the large biological molecules’ orbitals make one huge “cell-orbital”, which is structured according to the spiral fractal nature of quantum fields. Consciousness of single cells, multi cellular structures as e.g. organs, multi-cellular organisms and multi-individual colonies (like ants and human societies can thus be explained by deep quantum chemistry. When biochemical activity is strictly controlled by the quantum-mechanical super-orbital of the cell, this orbital can deliver energetic quanta as biological information, distributed through many fractal levels of the cell to guide form and behavior of an individual single or a multi-cellular organism. The top level of information is the consciousness of the cell or organism, which controls all the biochemical processes. By this speculative work inspired by Penrose and Hameroff we hope to inspire other researchers to formulate more strict and mathematically correct hypothesis on the complex and coherence nature of matter, life and consciousness.

  8. Summer carbonate chemistry dynamics in the Southern Yellow Sea and the East China Sea: Regional variations and controls

    Science.gov (United States)

    Qu, Baoxiao; Song, Jinming; Yuan, Huamao; Li, Xuegang; Li, Ning; Duan, Liqin; Chen, Xin; Lu, Xi

    2015-12-01

    Surface partial pressure of CO2 (pCO2) and pertinent parameters (i.e., pH, total alkalinity, dissolved oxygen, chlorophyll a) were investigated in the southern Yellow Sea (SYS) and the East China Sea (ECS) basing on two surveys conducted in June and August of 2013. The results suggested carbonate chemistry dynamics and related controlling factors were provided with significant temporal and spatial variations in different subregions of these two continental shelf seas. The western of SYS (SYSW) was CO2-undersaturated both in June and August, with the average FCO2 -1.88 mmol m-2 d-1 and -3.72 mmol m-2 d-1, respectively. The phytoplankton initiated CO2-absorption and the suspended sediment induced CO2-emission jointly controlled the air-sea CO2 exchange there. The center of SYS (SYSC) also behaved as an obvious CO2 sink (-1.57 mmol m-2 d-1and -3.99 mmol m-2 d-1 in June and August, respectively), probably due to elevated TA/DIC ratio and the subsequent effects of spring bloom. As for the Yangtze River estuary (YRE), it changed from an obvious CO2 sink (-1.28 mmol m-2 d-1) in June into a very weak CO2 source (0.04 mmol m-2 d-1) in August. This change was probably associated with the rising of seawater temperature and monthly variation of Yangtze River discharge. The inner shelf of ECS (ECSS) experienced obvious air-sea CO2 flux changes during from June (-8.88 mmol m-2 d-1) to August (-0.36 mmol m-2 d-1) as well. Biological DIC consumption in the upper layer and DIC regenerated from respiration in the subsurface jointly controlled this pCO2 variation. As a whole, the SYS and ECS acted as an obvious CO2 sink during summer and could absorb atmospheric CO2 with the average air-sea flux (FCO2) -2.68 mmol m-2 d-1. The summary of air-sea CO2 flux in the ECS and SYS during recent two decades indicated the ECS served as quite a stable CO2 sink, whereas the SYS experienced obvious change. Discharge of Yangtze River and anthropogenic nutrients loading could profoundly affect the

  9. Dynamic production scheduling in virtual cellular manufacturing systems

    OpenAIRE

    马俊; Ma, Jun

    2012-01-01

    Manufacturing companies must constantly improve productivity to respond to dynamic changes in customer demand in order to maintain their competitiveness and marketshares. This requires manufacturers to adopt more efficient methodologies to design and control their manufacturing systems. In recent decades, virtual cellular manufacturing (VCM), as an advanced manufacturing concept, has attracted increasing attention in the research community, because traditional cellular manufacturing is inadeq...

  10. High temperature on-line monitoring of water chemistry and corrosion control in water cooled power reactors. Report of a co-ordinated research project 1995-1999

    International Nuclear Information System (INIS)

    This report documents the results of the Co-ordinated Research Project (CRP) on High Temperature On-line Monitoring of Water Chemistry and Corrosion in Water Cooled Power Reactors (1995-1999). This report attempts to provide both an overview of the state of the art with regard to on-line monitoring of water chemistry and corrosion in operating reactors, and technical details of the important contributions made by programme participants to the development and qualification of new monitoring techniques. The WACOL CRP is a follow-up to the WACOLIN (Investigations on Water Chemistry Control and Coolant Interaction with Fuel and Primary Circuit Materials in Water Cooled Power Reactors) CRP conducted by the IAEA from 1986 to 1991. The WACOLIN CRP, which described chemistry, corrosion and activity-transport aspects, clearly showed the influence of water chemistry on corrosion of both fuel and reactor primary-circuit components, as well as on radiation fields. It was concluded that there was a fundamental need to monitor water-chemistry parameters in real time, reliably and accurately. The objectives of the WACOL CRP were to establish recommendations for the development, qualification and plant implementation of methods and equipment for on-line monitoring of water chemistry and corrosion. Chief investigators from 18 organizations representing 15 countries provided a variety of contributions aimed at introducing proven monitoring techniques into plants on a regular basis and filling the gaps between plant operator needs and available monitoring techniques. The CRP firmly demonstrated that in situ monitoring is able to provide additional and valuable information to plant operators, e.g. ECP, high temperature pH and conductivity. Such data can be obtained promptly, i.e. in real time and with a high degree of accuracy. Reliable techniques and sensor devices are available which enable plant operators to obtain additional information on the response of structural materials in

  11. Social Chemistry

    OpenAIRE

    Lichtfouse, Eric; Schwarzbauer, Jan; Robert, Didier

    2012-01-01

    International audience This article is both an essay to propose social chemistry as a new scientific discipline, and a preface of the book Environmental Chemistry for a Sustainable World. Environmental chemistry is a fast emerging discipline aiming at the understanding the fate of pollutants in ecosystems and at designing novel processes that are safe for ecosystems. Past pollution should be cleaned, future pollution should be predicted and avoided (Lichtfouse et al., 2005a). Such advices ...

  12. Computational chemistry

    OpenAIRE

    Truhlar, Donald G.; McKoy, Vincent

    2000-01-01

    Computational chemistry has come of age. With significant strides in computer hardware and software over the last few decades, computational chemistry has achieved full partnership with theory and experiment as a tool for understanding and predicting the behavior of a broad range of chemical, physical, and biological phenomena. The Nobel Prize award to John Pople and Walter Kohn in 1998 highlighted the importance of these advances in computational chemistry. With massively parallel computers ...

  13. Bioinorganic Chemistry

    OpenAIRE

    Bertini, Ivano; Gray, Harry B.; Lippard, Stephen J.; Valentine, Joan Selverstone

    1994-01-01

    This book covers material that could be included in a one-quarter or one-semester course in bioinorganic chemistry for graduate students and advanced undergraduate students in chemistry or biochemistry. We believe that such a course should provide students with the background required to follow the research literature in the field. The topics were chosen to represent those areas of bioinorganic chemistry that are mature enough for textbook presentation. Although each chapter presents material...

  14. DOE fundamentals handbook: Chemistry

    International Nuclear Information System (INIS)

    The Chemistry Handbook was developed to assist nuclear facility operating contractors in providing operators, maintenance personnel, and the technical staff with the necessary fundamentals training to ensure a basic understanding of chemistry. The handbook includes information on the atomic structure of matter; chemical bonding; chemical equations; chemical interactions involved with corrosion processes; water chemistry control, including the principles of water treatment; the hazards of chemicals and gases, and basic gaseous diffusion processes. This information will provide personnel with a foundation for understanding the chemical properties of materials and the way these properties can impose limitations on the operation of equipment and systems

  15. EERE Quality Control Workshop Final Report: Proceedings from the EERE Quality Control Workshop, in support of the DOE Clean Energy Manufacturing Initiative; Golden, Colorado, December 9-10, 2013

    Energy Technology Data Exchange (ETDEWEB)

    2014-05-01

    The U.S. Department of Energy Office of Energy Efficiency & Renewable Energy (EERE) has recognized the cross-cutting, pre-competitive and enabling nature of quality control for a wide range of clean energy technologies. As such, the Fuel Cell Technologies Office, Solar Energy Technologies Office, Vehicle Technologies Office, Building Technologies Office, and Advanced Manufacturing Office decided to explore needs and potential cross-office synergies in this area by holding the EERE Quality Control Workshop, in support of the DOE Clean Energy Manufacturing Initiative. This report summarizes the purpose and scope of the workshop; reviews the current status and state-of-the-art for in-line quality control; summarizes the results from three breakout sessions; and presents conclusions and recommendations.

  16. Additive Manufacturing of IN100 Superalloy Through Scanning Laser Epitaxy for Turbine Engine Hot-Section Component Repair: Process Development, Modeling, Microstructural Characterization, and Process Control

    Science.gov (United States)

    Acharya, Ranadip; Das, Suman

    2015-09-01

    This article describes additive manufacturing (AM) of IN100, a high gamma-prime nickel-based superalloy, through scanning laser epitaxy (SLE), aimed at the creation of thick deposits onto like-chemistry substrates for enabling repair of turbine engine hot-section components. SLE is a metal powder bed-based laser AM technology developed for nickel-base superalloys with equiaxed, directionally solidified, and single-crystal microstructural morphologies. Here, we combine process modeling, statistical design-of-experiments (DoE), and microstructural characterization to demonstrate fully metallurgically bonded, crack-free and dense deposits exceeding 1000 μm of SLE-processed IN100 powder onto IN100 cast substrates produced in a single pass. A combined thermal-fluid flow-solidification model of the SLE process compliments DoE-based process development. A customized quantitative metallography technique analyzes digital cross-sectional micrographs and extracts various microstructural parameters, enabling process model validation and process parameter optimization. Microindentation measurements show an increase in the hardness by 10 pct in the deposit region compared to the cast substrate due to microstructural refinement. The results illustrate one of the very few successes reported for the crack-free deposition of IN100, a notoriously "non-weldable" hot-section alloy, thus establishing the potential of SLE as an AM method suitable for hot-section component repair and for future new-make components in high gamma-prime containing crack-prone nickel-based superalloys.

  17. Green Chemistry with Microwave Energy

    Science.gov (United States)

    Green chemistry utilizes a set of 12 principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture, and applications of chemical products (1). This newer chemical approach protects the environment by inventing safer and eco-friendl...

  18. Controlling the microstructure and properties of wire arc additive manufactured Ti–6Al–4V with trace boron additions

    International Nuclear Information System (INIS)

    This study demonstrates that trace boron addition to Ti–6Al–4V coupons produced by additive layer manufacturing is an effective way to eliminate the deleterious anisotropic microstructures often encountered with this manufacturing technique. Trace boron additions (up to 0.13 wt.%) to this alloy eliminate grain boundary-α and colony-α, and instead produce a homogeneous α-microstructure consisting of fine equiaxed α-grains in both as-deposited and heat treated coupons. Prior-β grains remain columnar with boron addition but become narrower due to the wider solidification range and growth restricting effect of the boron solute. Compared to unmodified Ti–6Al–4V alloy, Ti–6Al–4V modified with trace boron additions showed up to 40% improvement in plasticity with no loss in strength under uniaxial compression at room temperature. Boron additions were found to inhibit twinning transmission that causes sudden large load drops during deformation of the unmodified Ti–6Al–4V alloy in the heat treated condition

  19. A manufacturing process for tubular blanks made of zircaloy 2 and internally plated with zirconium, with possibility of ultrasonic control of the zirconium thickness

    International Nuclear Information System (INIS)

    In order to be able to carry out ultrasonic measurement of the thickness of the zirconium coating on the inner side of nuclear fuel tubes made of zircaloy 2, a new process for the fabrication of plated tubular blanks is proposed: the plating is thermo-mechanically treated at one or more stages of the blank manufacturing, in order to control the grain size at precise levels on the zircaloy 2 (ASTM Index between 9 and 12) and on the zirconium (6 to 10); the grain size difference between the two material should remain larger than 2 ASTM indexes. 4 refs., 5 figs., 1 tab

  20. Looking at the future of manufacturing metrology: roadmap document of the German VDI/VDE Society for Measurement and Automatic Control

    Directory of Open Access Journals (Sweden)

    J. Berthold

    2013-02-01

    Full Text Available "Faster, safer, more accurately and more flexibly'' is the title of the "manufacturing metrology roadmap'' issued by the VDI/VDE Society for Measurement and Automatic Control (http://www.vdi.de/gma. The document presents a view of the development of metrology for industrial production over the next ten years and was drawn up by a German group of experts from research and industry. The following paper summarizes the content of the roadmap and explains the individual concepts of "Faster, safer, more accurately and more flexibly'' with the aid of examples.

  1. Manufacturing technology

    Energy Technology Data Exchange (ETDEWEB)

    Leonard, J.A.; Floyd, H.L.; Goetsch, B.; Doran, L. [eds.

    1993-08-01

    This bulletin depicts current research on manufacturing technology at Sandia laboratories. An automated, adaptive process removes grit overspray from jet engine turbine blades. Advanced electronic ceramics are chemically prepared from solution for use in high- voltage varistors. Selective laser sintering automates wax casting pattern fabrication. Numerical modeling improves performance of photoresist stripper (simulation on Cray supercomputer reveals path to uniform plasma). And mathematical models help make dream of low- cost ceramic composites come true.

  2. A framework for distributed manufacturing applications

    OpenAIRE

    Leitão, Paulo; Restivo, Francisco

    2000-01-01

    The new organisational structures used in world wide manufacturing systems require the development of distributed applications, which present solutions to their requirements. The work research in the distributed manufacturing control leads to emergent paradigms, such as Holonic Manufacturing Systems (HMS) and Bionic Manufacturing Systems (BMS), which translates the concepts from social organisations and biological systems to the manufacturing world. This paper present a Framework for the deve...

  3. Good chemistry

    OpenAIRE

    Petsko, Gregory A

    2004-01-01

    The subject matter in chemistry courses reflects almost nothing of the issues that chemists are interested in. It is important to formulate a set of topics - and a Medical College Admissions Test reflecting them - that would leave chemistry departments no choice but to change their teaching.

  4. The Recent Trend of the National and International Standard of Manufacturing Quality Control for Diagnostic X-ray Equipment

    International Nuclear Information System (INIS)

    Newly published IEC 60601-1-3 ; 2008 2nd Edition has two important meanings. First, Radiation Quality and Dose should make sure for safety of patient and staff in manufacturing diagnostic X-ray equipment. Second, it should be minimized of Leakage Radiation, Residual Radiation, and Stray Radiation. The requirement to make enactment or revision of national standard for diagnostic X-ray Equipment is as follows : 1. It should be adjusted the new standard to the recent IEC Publication under the consideration of the Korea medical circumstances. 2. For focus to the Radiation Safety, IEC 60601-1-3 (General requirements for radiation protection in diagnostic X-ray equipment) could be applied to the new regulation. It should be compact sentence. 3. A sudden Notification change should not be desired. It needs a enough time to make easy the circumstances.

  5. Laser in manufacturing

    CERN Document Server

    Davim, J Paulo

    2013-01-01

    Generally a laser (light amplification by stimulated emission of radiation) is defined as "a device which uses a quantum mechanical effect, stimulated emission, to generate a coherent beam of light from a lasing medium of controlled purity, size, and shape". Laser material processing represents a great number of methods, which are rapidly growing in current and different industrial applications as new alternatives to traditional manufacturing processes. Nowadays, the use of lasers in manufacturing is an emerging area with a wide variety of applications, for example, in electronics, molds an

  6. Enhanced Control of PWR Primary Coolant Water Chemistry Using Selective Separation Systems for Recovery and Recycle of Enriched Boric Acid

    Energy Technology Data Exchange (ETDEWEB)

    Ken Czerwinski; Charels Yeamans; Don Olander; Kenneth Raymond; Norman Schroeder; Thomas Robison; Bryan Carlson; Barbara Smit; Pat Robinson

    2006-02-28

    The objective of this project is to develop systems that will allow for increased nuclear energy production through the use of enriched fuels. The developed systems will allow for the efficient and selective recover of selected isotopes that are additives to power water reactors' primary coolant chemistry for suppression of corrosion attack on reactor materials.

  7. Patterned porous silicon photonic crystals with modular surface chemistry for spatial control of neural stem cell differentiation.

    Science.gov (United States)

    Huang, Tiffany H; Pei, Yi; Zhang, Douglas; Li, Yanfen; Kilian, Kristopher A

    2016-06-01

    We present a strategy to spatially define regions of gold and nanostructured silicon photonics, each with materials-specific surface chemistry, for azide-alkyne cycloaddition of different bioactive peptides. Neural stem cells are spatially directed to undergo neurogenesis and astrogenesis as a function of both surface properties and peptide identity. PMID:27173986

  8. Secondary soil phases controlling surface water chemistry during experimental acidification at the Bear Brook Watershed in Maine, USA

    Czech Academy of Sciences Publication Activity Database

    Navrátil, Tomáš; Norton, S. A.; Fernandez, I. J.; Diehl, M.

    Santa Cruz : University of Santa Cruz, 2006 - (Crow, S.). s. 158-158 [BIOGEOMON. 25.6.2006-30.6.2006, Santa Cruz, California] Institutional research plan: CEZ:AV0Z30130516 Keywords : experimental acidification * streamwater * chemistry * aluminum * sulfate Subject RIV: DD - Geochemistry

  9. Migration chemistry

    International Nuclear Information System (INIS)

    Migration chemistry, the influence of chemical -, biochemical - and physico-chemical reactions on the migration behaviour of pollutants in the environment, is an interplay between the actual natur of the pollutant and the characteristics of the environment, such as pH, redox conditions and organic matter content. The wide selection of possible pollutants in combination with varying geological media, as well as the operation of different chemical -, biochemical - and physico-chemical reactions compleactes the prediction of the influence of these processes on the mobility of pollutants. The report summarizes a wide range of potential pollutants in the terrestrial environment as well as a variety of chemical -, biochemical - and physico-chemical reactions, which can be expected to influence the migration behaviour, comprising diffusion, dispersion, convection, sorption/desorption, precipitation/dissolution, transformations/degradations, biochemical reactions and complex formation. The latter comprises the complexation of metal ions as well as non-polar organics to naturally occurring organic macromolecules. The influence of the single types of processes on the migration process is elucidated based on theoretical studies. The influence of chemical -, biochemical - and physico-chemical reactions on the migration behaviour is unambiguous, as the processes apparently control the transport of pollutants in the terrestrial environment. As the simple, conventional KD concept breaks down, it is suggested that the migration process should be described in terms of the alternative concepts chemical dispersion, average-elution-time and effective retention. (AB) (134 refs.)

  10. Additive Manufacturing of Ion Thruster Optics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Plasma Controls will manufacture and test a set of ion optics for electric propulsion ion thrusters using additive manufacturing technology, also known as 3D...

  11. A Promising Material by Using Residue Waste from Bisphenol A Manufacturing to Prepare Fluid-Loss-Control Additive in Oil Well Drilling Fluid

    Directory of Open Access Journals (Sweden)

    Zhi-Lei Zhang

    2013-01-01

    Full Text Available The residues mixture from Bisphenol A manufacturing process was analyzed. Fourier transform infrared (FTIR spectroscopy, gas chromatography-mass spectrometry (GC-MS, and nuclear magnetic resonance (NMR were used to characterize the residues. The results indicated that the residues were complex mixture of several molecules. 3-(2-Hydroxyphenyl-1,1,3-trimethyl-2,3-dihydro-1H-inden-5-ol and phenol were the main components of the residues. The technical feasibility of using it as phenol replacement in fluid-loss-control additive production was also investigated. The fluid-loss-control capacity of the novel additive was systematically investigated. It was discovered that the well fluid-loss performance of the prepared additive can be achieved, especially at high temperature.

  12. Quantum chemistry

    CERN Document Server

    Lowe, John P

    1993-01-01

    Praised for its appealing writing style and clear pedagogy, Lowe's Quantum Chemistry is now available in its Second Edition as a text for senior undergraduate- and graduate-level chemistry students. The book assumes little mathematical or physical sophistication and emphasizes an understanding of the techniques and results of quantum chemistry, thus enabling students to comprehend much of the current chemical literature in which quantum chemical methods or concepts are used as tools. The book begins with a six-chapter introduction of standard one-dimensional systems, the hydrogen atom,

  13. 77 FR 16158 - Current Good Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs...

    Science.gov (United States)

    2012-03-20

    ... Administration (FDA) is amending the packaging and labeling control provisions of the current good manufacturing..., 21 CFR part 211 is amended as follows: PART 211--CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED... Manufacturing Practice in Manufacturing, Processing, Packing, or Holding of Drugs; Revision of Certain...

  14. Preoccupation with Protecting Manufacturing? Preoccupation with Protecting Manufacturing?

    OpenAIRE

    Edward Tower; Alecia Waite

    2011-01-01

    This paper explores the relationship between manufacturing and growth rate in recent years. Authors undertake a simple cross-country analysis using UN data. When controlling for variables relevant to growth, find no significant relationship between the two variables.

  15. New trends and developments in radiation chemistry

    International Nuclear Information System (INIS)

    Radiation chemistry is a branch of chemistry that studies chemical transformations in materials exposed to high-energy radiations. It uses radiation as the initiator of chemical reactions. Practical applications of radiation chemistry today extend to many fields, including health care, food and agriculture, manufacturing, industrial pollution abatement, biotechnology and telecommunications. The important advantage of radiation chemistry lies in its ability to be used to produce, and study, almost any reactive atomic and molecular species playing a part in chemical reactions, synthesis, industrial processes, or in biological systems. The techniques are applicable to gaseous, liquid, solid, and heterogeneous systems. By combining different techniques of radiation chemistry with analytical chemistry, the reaction mechanism and kinetics of chemical reactions are studied. In November 1988 in Bologna, Italy, the IAEA convened an advisory group meeting to assess new trends and developments in radiation chemistry. The present publication includes most of the contributions presented at the meeting. Refs, figs and tabs

  16. Patterned porous silicon photonic crystals with modular surface chemistry for spatial control of neural stem cell differentiation

    Science.gov (United States)

    Huang, Tiffany H.; Pei, Yi; Zhang, Douglas; Li, Yanfen; Kilian, Kristopher A.

    2016-05-01

    We present a strategy to spatially define regions of gold and nanostructured silicon photonics, each with materials-specific surface chemistry, for azide-alkyne cycloaddition of different bioactive peptides. Neural stem cells are spatially directed to undergo neurogenesis and astrogenesis as a function of both surface properties and peptide identity.We present a strategy to spatially define regions of gold and nanostructured silicon photonics, each with materials-specific surface chemistry, for azide-alkyne cycloaddition of different bioactive peptides. Neural stem cells are spatially directed to undergo neurogenesis and astrogenesis as a function of both surface properties and peptide identity. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr08327c

  17. Conjugation chemistry through acetals toward a dextran-based delivery system for controlled release of siRNA

    KAUST Repository

    Cui, Lina

    2012-09-26

    New conjugation chemistry for polysaccharides, exemplified by dextran, was developed to enable the attachment of therapeutic or other functional moieties to the polysaccharide through cleavable acetal linkages. The acid-lability of the acetal groups allows the release of therapeutics under acidic conditions, such as that of the endocytic compartments of cells, regenerating the original free polysaccharide in the end. The physical and chemical behavior of these acetal groups can be adjusted by modifying their stereoelectronic and steric properties, thereby providing materials with tunable degradation and release rates. We have applied this conjugation chemistry in the development of water-soluble siRNA carriers, namely acetal-linked amino-dextrans, with various amine structures attached through either slow- or fast-degrading acetal linker. The carriers with the best combination of amine moieties and structural composition of acetals showed high in vitro transfection efficiency and low cytotoxicity in the delivery of siRNA. © 2012 American Chemical Society.

  18. Mathematical Modeling of Complex Reaction Systems for Computer-Aided Control and its Illustration on Atmospheric Chemistry

    Science.gov (United States)

    Amiryan, A.

    2015-12-01

    Modeling of sequential process has its own importance in Atmospheric Chemistry. Numerical calculations which allow to predict separate stages and components of chemical reaction make possible the reaction management, such is the new and perspective direction in chemical researches. Chemical processes basically pass multiple simple stages where various atoms and radicals participate. The complex chain of chemical reactionary systems complicates their research and the research is impossible without new methods of mathematical simulation and high technologies which allow not only to explain results of experiments but also to predict dynamics of processes. A new program package is suggested for solving research problems of chemical kinetics. The program is tested on different illustrative examples on Atmospheric Chemistry and installed in various scientific and educational institutions.

  19. Materials Chemistry

    CERN Document Server

    Fahlman, Bradley D

    2011-01-01

    The 2nd edition of Materials Chemistry builds on the strengths that were recognized by a 2008 Textbook Excellence Award from the Text and Academic Authors Association (TAA). Materials Chemistry addresses inorganic-, organic-, and nano-based materials from a structure vs. property treatment, providing a suitable breadth and depth coverage of the rapidly evolving materials field. The 2nd edition continues to offer innovative coverage and practical perspective throughout. After briefly defining materials chemistry and its history, seven chapters discuss solid-state chemistry, metals, semiconducting materials, organic "soft" materials, nanomaterials, and materials characterization. All chapters have been thoroughly updated and expanded with, for example, new sections on ‘soft lithographic’ patterning, ‘click chemistry’ polymerization, nanotoxicity, graphene, as well as many biomaterials applications. The polymer and ‘soft’ materials chapter represents the largest expansion for the 2nd edition. Each ch...

  20. Introductory Chemistry

    OpenAIRE

    Baron, Mark; Gonzalez-Rodriguez, Jose; Stevens, Gary; Gray, Nathan; Atherton, Thomas; Winn, Joss

    2010-01-01

    Teaching and Learning resources for the 1st Year Introductory Chemistry course (Forensic Science). 30 credits. These are Open Educational Resources (OER), made available for re-use under a Creative Commons license.

  1. Analytical chemistry

    International Nuclear Information System (INIS)

    This book is comprised of nineteen chapters, which describes introduction of analytical chemistry, experimental error and statistics, chemistry equilibrium and solubility, gravimetric analysis with mechanism of precipitation, range and calculation of the result, volume analysis on general principle, sedimentation method on types and titration curve, acid base balance, acid base titration curve, complex and firing reaction, introduction of chemical electro analysis, acid-base titration curve, electrode and potentiometry, electrolysis and conductometry, voltammetry and polarographic spectrophotometry, atomic spectrometry, solvent extraction, chromatograph and experiments.

  2. Cluster Chemistry

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    @@ Cansisting of eight scientists from the State Key Laboratory of Physical Chemistry of Solid Surfaces and Xiamen University, this creative research group is devoted to the research of cluster chemistry and creation of nanomaterials.After three-year hard work, the group scored a series of encouraging progresses in synthesis of clusters with special structures, including novel fullerenes, fullerene-like metal cluster compounds as well as other related nanomaterials, and their properties study.

  3. Green Chemistry

    Energy Technology Data Exchange (ETDEWEB)

    Collison, Melanie

    2011-05-15

    Green chemistry is the science of chemistry used in a way that will not use or create hazardous substances. Dr. Rui Resendes is working in this field at GreenCentre Canada, an offshoot of PARTEQ Innovations in Kingston, Ontario. GreenCentre's preliminary findings suggest their licensed product {sup S}witchable Solutions{sup ,} featuring 3 classes of solvents and a surfactant, may be useful in bitumen oil sands extraction.

  4. A control-monitoring-maintenance framework based on Petri net with objects in fl exible manufacturing system. Application to a robot-driven fl exible cell

    Directory of Open Access Journals (Sweden)

    Eduardo Rocha Loures

    2010-02-01

    Full Text Available

    The growing complexity of systems and the need for executing large projects have led to the development of complex fl exible manufacturing systems (FMS demanding specifi c control-monitoring architectures. The problem of failure occurrence tends
    to increase according to this complexity leading to time-consuming tasks as the localisation and repairing. The occurrence of failures during the exploitation stage can deeply modify the FMS performances or its availability. In this context, the maintenance integration into a control-monitoring system becomes an important issue, improving production time and minimizing unplanned costly breakdowns of FMS. We want to investigate the problem of triggering the maintenance, giving a useful decision support tool to evaluate the system availability since the control system’s early design stage. It also results in improvement of the system’s functionality in terms of effi ciency, productivity and quality. This paper proposes a control- monitoringmaintenance architecture (CMM for FMS based on Petri nets with objects (PNO, where stochastic rates are associated to the modelling of maintenance planning. This
    framework is based on a modular and hierarchic model structured in CMM modules. The integration is based on a development methodology in which the maintenance
    aspects and policies are taken into account from the conception (modelling stage. These efforts acts as a basis for the control architecture of a robot-driven fl exible cell, connected to the Ethernet-TCP/IP.

  5. Water-Shale interactions in bench-top and high pressure/high temperature autoclave experiments: Identifying geochemical reaction controlling flow back water chemistry

    Science.gov (United States)

    Mickler, P. J.; Lu, J.; Nicot, J.

    2013-12-01

    An important side effect of hydraulic fracturing (HF) in shale gas wells is the production of saline flow-back water. This water often contains total dissolved soil (TDS) concentrations greater than 100,000 ppm which requires expensive treatment and disposal of the produced water. Possible origins of the high TDS content include: 1. Mixing of fresh HF-fluids with highly saline pore fluids in the targeted shale. 2. Migration and mixing of saline brines by newly-formed fractures into the HF-water from neighboring formations. 3. Water rock interactions between the targeted shale and HF-water that include mineral dissolution, pyrite oxidation buffered by carbonate dissolution and cation exchange in newly hydrated clay minerals.. These possibilities are not mutually exclusive and all may be operating to alter flow-back water chemistry. This study will examine geochemical reactions between a productive Gulf Coast shale and manufactured HF-waters using sealed bench top experiments and high temperature/high pressure autoclave experiments. The samples of the shale were collected from core material housed at The Bureau of Economic Geology collected from two wells. The manufactured HF-waters were produced by mixing NaCl, KCl and CaCl2 salts with De-ionized water at approximately 0, 2000 and 20,000 ppm. During experiments, elements that show large increases in aqueous concentrations are Na, Cl, Ca and SO4. Simultaneous increases in Na and Cl, coupled with high Cl/Br ratios, suggest halite dissolution rather than pore space brine is responsible for Na and Cl concentrations. Simultaneous increase in Ca and SO4 suggest anhydrite dissolution. (SEM imaging shows that anhydrite crystals are usually embedded with the framework mineral grains, rather than precipitated in pores during sample drying, which suggests mineral source of Ca and SO4, possibly for Na and Cl as well). Pyrite oxidation and calcium carbonate dissolution were not significant due to no decrease in pH and no

  6. New methods of in situ metrology and process control for EBF3 Additive Manufacturing, a feasibility study Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed innovation is a methodology for advanced process control and deposition analysis built around using signals generated by beam-component interactions in...

  7. Competitive forces and the levers of control framework in a manufacturing setting: A tale of a multinational subsidiary

    OpenAIRE

    Zahirul Hoque; Maybelle Chia

    2012-01-01

    Purpose – The purpose of this article is to explore how the strategic change following a corporate takeover impacted the nature and extent of use of the firm's management control systems (MCS), in particular its performance measurement system (PMS). Design/methodology/approach – This paper uses Michael Porter's theory of competitive advantage and Robert Simons' levers of control framework to illustrate and interpret changes in the PMS within an Australian multinational subsidiary following it...

  8. Comparative analysis of quality assurance systems which effectively control, review and verify the quality of components manufactured for liquid metal cooled fast breeder reactors within the EEC

    International Nuclear Information System (INIS)

    Comparative analyses are made of Quality Assurance Systems, by techniques and the methodology used, for the manufacture of component parts for the Liquid Metal Cooled Fast Breeder Reactor (LMFBR) within the EEC. Two differing alternative systems are presented in the analysis. First, a tabulated analytical treatment which analyses 14 codes and standards relating to Quality Assurance which can be applied to LMFBR's. The comparison equates equivalent clauses between codes and standards followed by an analysis of individual clauses in tabular form, the International Standard ISO 6215. A statistical summary and recommendations conclude this analysis. The second alternative system used in the comparison is a descriptive analytical method applied to 9 selected codes and standards relating to Quality Assurance based on the 13 criteria of the International IAEA Code of Practice no. 50 C.QA entitled ''Quality Assurance for Safety in Nuclear Power Plants''. An investigation is then made of the state of the art on the subject of classification of component parts bearing generally on Quality Assurance. The method of classification is segregated into General, Safety and Inspection categories. A summary of destructive and non destructive controls that may be applied during the manufacture of LMFBR components is given, together with tests that may be applied to selected components, namely Primary Tank, Secondary Sodium Pump and the Primary Cold Trap allocated to Safety Classes, 1, 2 and 3 respectively. The report concludes with a summary of typical records produced at the delivery of a component

  9. Process chemistry {ampersand} statistics quality assurance plan

    Energy Technology Data Exchange (ETDEWEB)

    Meznarich, H.K.

    1996-08-01

    This document provides quality assurance guidelines and quality control requirements for Process Chemistry and Statistics. This document is designed on the basis of Hanford Analytical Services Quality Assurance Plan (HASQAP) technical guidelines and is used for governing process chemistry activities.

  10. Good manufacturing practice

    International Nuclear Information System (INIS)

    In this presentation author deals with the Implementation of good manufacturing practice for radiopharmaceuticals. The presentation is divided into next parts: Batch size; Expiration date; QC Testing; Environmental concerns; Personnel aspects; Radiation concerns; Theoretical yields; Sterilizing filters; Control and reconciliation of materials and components; Product strength; In process sampling and testing; Holding and distribution; Drug product inspection; Buildings and facilities; Renovations at BNL for GMP; Aseptic processing and sterility assurance; Process validation and control; Quality control and drug product stability; Documentation and other GMP topics; Building design considerations; Equipment; and Summary

  11. 75 FR 37295 - Control of Immediate Precursor Used in the Illicit Manufacture of Fentanyl as a Schedule II...

    Science.gov (United States)

    2010-06-29

    ... List I Chemical'' (72 FR 20039, April 23, 2007), followed by a Final Rule (73 FR 43355, July 25, 2008... laboratories. Under a separate rulemaking first published as an interim rule on April 23, 2007 (72 FR 20039), followed by a final rule on July 25, 2008 (73 FR 43355), DEA has controlled the precursor NPP as a List...

  12. 76 FR 17778 - Control of Ergocristine, a Chemical Precursor Used in the Illicit Manufacture of Lysergic Acid...

    Science.gov (United States)

    2011-03-31

    ... Proposed Rulemaking (75 FR 8287), such controls are deemed necessary for law enforcement to identify... domestically; the other two are based in Germany and the Czech Republic. This rule implements both domestic and... forth in Sections 3(a) and 3(b)(2) of Executive Order 12988, Civil Justice Reform. Executive Order...

  13. Radiation Chemistry

    Science.gov (United States)

    Wojnárovits, L.

    Ionizing radiation causes chemical changes in the molecules of the interacting medium. The initial molecules change to new molecules, resulting in changes of the physical, chemical, and eventually biological properties of the material. For instance, water decomposes to its elements H2 and O2. In polymers, degradation and crosslinking take place. In biopolymers, e.g., DNS strand breaks and other alterations occur. Such changes are to be avoided in some cases (radiation protection), however, in other cases they are used for technological purposes (radiation processing). This chapter introduces radiation chemistry by discussing the sources of ionizing radiation (radionuclide sources, machine sources), absorption of radiation energy, techniques used in radiation chemistry research, and methods of absorbed energy (absorbed dose) measurements. Radiation chemistry of different classes of inorganic (water and aqueous solutions, inorganic solids, ionic liquids (ILs)) and organic substances (hydrocarbons, halogenated compounds, polymers, and biomolecules) is discussed in concise form together with theoretical and experimental backgrounds. An essential part of the chapter is the introduction of radiation processing technologies in the fields of polymer chemistry, food processing, and sterilization. The application of radiation chemistry to nuclear technology and to protection of environment (flue gas treatment, wastewater treatment) is also discussed.

  14. Mitigation of organically bound sulphate from water treatment plants at Bruce NGS and impact on steam generator secondary side chemistry control

    International Nuclear Information System (INIS)

    Bruce Power is the source of more than 20 per cent of Ontario's electricity and currently operates six reactor units at the Bruce Nuclear Generating Station A (two units) and B (four units) stations located on Lake Huron. This paper discusses the challenges faced and operating experience (OPEX) gained in meeting WANO 1.0 chemistry performance objectives for steam generator secondary side chemistry control, particularly with control of steam generator sulphates. A detailed sampling and analysis program conducted as part of this study concluded that a major contributor to steam generator (SG) elevated sulphates is Organically Bound Sulphate (OBS) in Water Treatment Plants (WTP) effluent. The Bruce A and B WTPs consist of clarification with downstream sand and carbon filtration for Lake Water pre-treatment, which are followed by conventional Ion Exchange (IX) demineralization. Samples taken from various locations in the process stream were analyzed for a variety of parameters including both organic bound and inorganic forms of sulphate. The results are inconclusive with respect to finding the definitive source of OBS. This is primarily due to the condition that the OBS in the samples, which are in relatively low levels, are masked during chemical analysis by the considerably higher inorganic sulphate background. Additionally, it was also determined that on-line Total Organic Carbon (TOC) levels at different WTP locations did not always correlate well with OBS levels in the effluent, such that TOC could not be effectively used as a control parameter to improve OBS performance of the WTP operation. Improvement efforts at both plants focused on a number of areas including optimization of clarifier operation, replacement of IX resins, addition of downstream mobile polishing trailers, testing of new resins and adsorbents, pilot-scale testing with a Reverse Osmosis (RO) rig, review of resin regeneration and backwashing practices, and operating procedure improvements

  15. Arc-welding process control based on back face thermography: application to the manufacturing of nuclear steam generators

    OpenAIRE

    Cobo García, Adolfo; Mirapeix Serrano, Jesús María; Conde Portilla, Olga María; García Allende, Pilar Beatriz; Madruga Saavedra, Francisco Javier; López Higuera, José Miguel

    2007-01-01

    The possibility of reducing defects in the arc welding process has attracted research interest, particularly, in the aerospace and nuclear sectors where the resulting weld quality is a major concern and must be assured by costly, time-consuming, non-destructive testing (NDT) procedures. One possible approach is the analysis of a measurand correlated with the formation of defects, from which a control action is derived. Among others, the thermographic analysis of the weld pool and the heat-aff...

  16. Approach to mitigate intergranular stress corrosion cracking and dose rate reduction rate by water chemistry control in Tokai-2

    International Nuclear Information System (INIS)

    The Japan Atomic Power Company (JAPC) had been working on material replacement and measures to mitigate stress in order to maintain the integrity of the structural material of Tokai-Daini nuclear power plant (Tokai-2, BWR, 1,100 MWe; commercial operation started on November 28, 1978). In addition, as Stress Corrosion Cracking (SCC) environmental mitigation measures, we have been reducing the sulfate ion concentration in the reactor water by improving the regeneration method of the ion exchange resin at condensate purification system. Furthermore, in conducting the SCC environmental mitigation measures by applying hydrogen water chemistry (HWC) and HWC during start-up (HDS), we have been reducing the oxidizing agent concentration in the reactor water. On the other hand, as a plant that has not installed condensate filters, we have been working on feed water iron concentration reduction measures in Tokai-2 as part of the dose reduction measures. Therefore, we have improved condensate demineralizer's ion exchange resin and the ion exchange resin cleaning method using the ARCS (Advanced Resin Cleaning System) in order to improve the iron removal performance of condensate demineralizer. This document reports the improvement effect of the SCC environmental mitigation measures and the dose reduction measures by water chemistry management at Tokai-2. In addition, the dose reduction effect of the recently applied zinc injection, and the Electrochemical Corrosion Potential (ECP) monitoring plan under the On-Line Noble Chemical Addition (OLNC™) to be implemented later shall be introduced. (author)

  17. Analytical Chemistry Laboratory

    Science.gov (United States)

    Anderson, Mark

    2013-01-01

    The Analytical Chemistry and Material Development Group maintains a capability in chemical analysis, materials R&D failure analysis and contamination control. The uniquely qualified staff and facility support the needs of flight projects, science instrument development and various technical tasks, as well as Cal Tech.

  18. Quantum chemistry

    CERN Document Server

    Lowe, John P

    2006-01-01

    Lowe's new edition assumes little mathematical or physical sophistication and emphasizes an understanding of the techniques and results of quantum chemistry. It can serve as a primary text in quantum chemistry courses, and enables students and researchers to comprehend the current literature. This third edition has been thoroughly updated and includes numerous new exercises to facilitate self-study and solutions to selected exercises.* Assumes little initial mathematical or physical sophistication, developing insights and abilities in the context of actual problems* Provides thorough treatment

  19. Polymer Chemistry

    Science.gov (United States)

    Williams, Martha; Roberson, Luke; Caraccio, Anne

    2010-01-01

    This viewgraph presentation describes new technologies in polymer and material chemistry that benefits NASA programs and missions. The topics include: 1) What are Polymers?; 2) History of Polymer Chemistry; 3) Composites/Materials Development at KSC; 4) Why Wiring; 5) Next Generation Wiring Materials; 6) Wire System Materials and Integration; 7) Self-Healing Wire Repair; 8) Smart Wiring Summary; 9) Fire and Polymers; 10) Aerogel Technology; 11) Aerogel Composites; 12) Aerogels for Oil Remediation; 13) KSC's Solution; 14) Chemochromic Hydrogen Sensors; 15) STS-130 and 131 Operations; 16) HyperPigment; 17) Antimicrobial Materials; 18) Conductive Inks Formulations for Multiple Applications; and 19) Testing and Processing Equipment.

  20. Design and manufacture of an ultrasonic inspection device for the friction welds in reactor vessel control rod drive mechanism housings

    International Nuclear Information System (INIS)

    The control rod drive mechanism housings of a PWR reactor vessel consist of a stainless steel flange and a Ni-Cr-Fe alloy tube, assembled by friction welding. The properties of the interface and the nature of the adjacent materials require the development of a specific ultrasonic inspection technique which could be easily automated, considering the number of parts involved (77 parts per 1300 MWe reactor vessel). The part has the general shape of a tube (inside diameter: 70 mm, outside diameter: 103 mm). The transition between both forged parent materials (stainless steel/Ni-Cr-Fe alloy) is obtained by a very thin interface, whose general orientation is normal to the tube centerline. The heat affected zone has generally a coarser and more irregular structure than that observed in the parent materials. The design and development were carried out using a prototype machine on test-pieces representative of a control rod drive mechanism housing, and containing the following artificial reflectors: notches obtained by electro-discharge machining on the inside and outside surfaces, on each side of the interface; planar artificial defects, parallel to the interface. These defects, obtained from 2 flat bottomed holes, drilled into the mock-up constituent parts, were conveyed to the interface during friction welding

  1. Ethanolic carbon-11 chemistry: The introduction of green radiochemistry

    International Nuclear Information System (INIS)

    The principles of green chemistry have been applied to a radiochemistry setting. Eleven carbon-11 labeled radiopharmaceuticals have been prepared using ethanol as the only organic solvent throughout the entire manufacturing process. The removal of all other organic solvents from the process simplifies production and quality control (QC) testing, moving our PET Center towards the first example of a green radiochemistry laboratory. All radiopharmaceutical doses prepared are suitable for clinical use. - Highlights: • We report application of the principles of green chemistry to a radiochemistry setting. • Radiopharmaceuticals are prepared using ethanol as the only organic solvent. • Green radiochemistry simplifies production and QC in busy clinical production laboratories. • Residual solvent analysis can be relegated to a quarterly or annual QC test

  2. Power electronic modules design and manufacture

    CERN Document Server

    Sheng, William W

    2004-01-01

    IntroductionSelection ProcedureMaterialsInsulating Substrate and MetallizationBase PlateBonding MaterialPower Interconnection and TerminalEncapsulantPlastic Case and Cover Manufacturing of Power IGBT ModulesManufacturing Process Process Control/Long-Term ReliabilityManufacturing FacilitiesManufacturing Flow Charts DesignThermal ManagementCircuit PartitioningDesign Guidelines and ConsiderationsThermal Results of Different Samples

  3. Nanophotonics and supramolecular chemistry

    Science.gov (United States)

    Ariga, Katsuhiko; Komatsu, Hirokazu; Hill, Jonathan P.

    2013-10-01

    Supramolecular chemistry has become a key area in emerging bottom-up nanoscience and nanotechnology. In particular, supramolecular systems that can produce a photonic output are increasingly important research targets and present various possibilities for practical applications. Accordingly, photonic properties of various supramolecular systems at the nanoscale are important in current nanotechnology. In this short review, nanophotonics in supramolecular chemistry will be briefly summarized by introducing recent examples of control of photonic responses of supramolecular systems. Topics are categorized according to the fundamental actions of their supramolecular systems: (i) self-assembly; (ii) recognition; (iii) manipulation.

  4. Characterization and stability of gold nanoparticles depending on their surface chemistry: Contribution of capillary zone electrophoresis to a quality control.

    Science.gov (United States)

    Pallotta, Arnaud; Boudier, Ariane; Leroy, Pierre; Clarot, Igor

    2016-08-26

    Four kinds of gold nanoparticles (AuNP) quite similar in terms of gold core size (ca. 5nm) and shape (spherical) but differing by their surface chemistry (either negatively, or positively charged, or neutral) were synthesized. They were analyzed using both the classical physicochemical approach (spectrophotometry, dynamic light scattering coupled or not to electrophoresis and transmission electron microscopy) and capillary zone electrophoresis equipped with photodiode array detection. The results obtained by both methodologies (related to Surface Plasmon Band-maximal absorbance wavelength-, and zeta potential and electrophoretic mobilities) were well correlated. Moreover, taking advantage of the separation method, the sample heterogeneity was evaluated and an impurity profile was extracted. This allowed setting some specifications which were then applied on the one hand to a batch-to-batch survey to declare NP as conform or not after production and on the other hand to a stability study. PMID:27435685

  5. Strong Coupling between Nanofluidic Transport and Interfacial Chemistry: How Defect Reactivity Controls Liquid-Solid Friction through Hydrogen Bonding.

    Science.gov (United States)

    Joly, Laurent; Tocci, Gabriele; Merabia, Samy; Michaelides, Angelos

    2016-04-01

    Defects are inevitably present in nanofluidic systems, yet the role they play in nanofluidic transport remains poorly understood. Here, we report ab initio molecular dynamics (AIMD) simulations of the friction of liquid water on defective graphene and boron nitride sheets. We show that water dissociates at certain defects and that these "reactive" defects lead to much larger friction than the "nonreactive" defects at which water molecules remain intact. Furthermore, we find that friction is extremely sensitive to the chemical structure of reactive defects and to the number of hydrogen bonds they can partake in with the liquid. Finally, we discuss how the insight obtained from AIMD can be used to quantify the influence of defects on friction in nanofluidic devices for water treatment and sustainable energy harvesting. Overall, we provide new insight into the role of interfacial chemistry on nanofluidic transport in real, defective systems. PMID:27012818

  6. Organic chemistry

    International Nuclear Information System (INIS)

    The activities of the mycotoxin research group are discussed. This includes the isolation and structure determination of mycotoxins, plant products, the biosyntheris of mycotoxins, the synthesis and characteristics of steroids, the synthesis and mechanistic aspects of heterocyclic chemistry and the functionality of steroids over long distances. Nmr spectra and mass spectroscopy are some of the techniques used

  7. Chemistry Notes

    Science.gov (United States)

    School Science Review, 1972

    1972-01-01

    Short articles on the kinetics of the hydrogen peroxide-iodide ion reaction, simulation of fluidization catalysis, the use of Newman projection diagrams to represent steric relationships in organic chemistry, the use of synthetic substrates for proteolytic enzyme reactions, and two simple clock reactions"--hydrolysis of halogenoalkanes and…

  8. Identification of major sources controlling groundwater chemistry from a hard rock terrain — A case study from Mettur taluk, Salem district, Tamil Nadu, India

    Science.gov (United States)

    Srinivasamoorthy, K.; Chidambaram, S.; Prasanna, M. V.; Vasanthavihar, M.; Peter, John; Anandhan, P.

    2008-02-01

    The study area Mettur forms an important industrial town situated NW of Salem district. The geology of the area is mainly composed of Archean crystalline metamorphic complexes. To identify the major process activated for controlling the groundwater chemistry an attempt has been made by collecting a total of 46 groundwater samples for two different seasons, viz., pre-monsoon and post-monsoon. The groundwater chemistry is dominated by silicate weathering and (Na + Mg) and (Cl + SO4) accounts of about 90% of cations and anions. The contribution of (Ca + Mg) and (Na + K) to total cations and HCO3 indicates the domination of silicate weathering as major sources for cations. The plot for Na to Cl indicates higher Cl in both seasons, derived from Anthropogenic (human) sources from fertilizer, road salt, human and animal waste, and industrial applications, minor representations of Na also indicates source from weathering of silicate-bearing minerals. The plot for Na/Cl to EC indicates Na released from silicate weathering process which is also supported by higher HCO3 values in both the seasons. Ion exchange process is also activated in the study area which is indicated by shifting to right in plot for Ca + Mg to SO4 + HCO3. The plot of Na-Cl to Ca + Mg-HCO3-SO4 confirms that Ca, Mg and Na concentrations in groundwater are derived from aquifer materials. Thermodynamic plot indicates that groundwater is in equilibrium with kaolinite, muscovite and chlorite minerals. Saturation index of silicate and carbonate minerals indicate oversaturation during pre-monsoon and undersaturation during post-monsoon, conforming dissolution and dilution process. In general, water chemistry is guided by complex weathering process, ion exchange along with influence of Cl ions from anthropogenic impact.

  9. Identification of major sources controlling groundwater chemistry from a hard rockterrain – A case study from Mettur taluk, Salem district, Tamil Nadu, India

    Indian Academy of Sciences (India)

    K Srinivasamoorthy; S Chidambaram; M V Prasanna; John Peter; P Anandhan

    2008-02-01

    The study area Mettur forms an important industrial town situated NW of Salem district. The geology of the area is mainly composed of Archean crystalline metamorphic complexes. To identify the major process activated for controlling the groundwater chemistry an attempt has been made by collecting a total of 46 groundwater samples for two different seasons, viz., pre-monsoon and post-monsoon. The groundwater chemistry is dominated by silicate weathering and (Na + Mg) and (Cl + SO4) accounts of about 90% of cations and anions. The contribution of (Ca +Mg) and (Na + K) to total cations and HCO3 indicates the domination of silicate weathering as major sources for cations. The plot for Na to Cl indicates higher Cl in both seasons, derived from Anthropogenic (human) sources from fertilizer, road salt, human and animal waste, and industrial applications, minor representations of Na also indicates source from weathering of silicate-bearing minerals. The plot for Na/Cl to EC indicates Na released from silicate weathering process which is also supported by higher HCO3 values in both the seasons. Ion exchange process is also activated in the study area which is indicated by shifting to right in plot for Ca +Mg to SO4 + HCO3. The plot of Na − Cl to Ca +Mg − HCO3 − SO4 confirms that Ca, Mg and Na concentrations in groundwater are derived from aquifer materials. Thermodynamic plot indicates that groundwater is in equilibrium with kaolinite, muscovite and chlorite minerals. Saturation index of silicate and carbonate minerals indicate oversaturation during pre-monsoon and undersaturation during post-monsoon, conforming dissolution and dilution process. In general, water chemistry is guided by complex weathering process, ion exchange along with influence of Cl ions from anthropogenic impact.

  10. Chemistry of sex attraction.

    OpenAIRE

    Roelofs, W L

    1995-01-01

    The chemical communication system used to attract mates involves not only the overt chemical signals but also indirectly a great deal of chemistry in the emitter and receiver. As an example, in emitting female moths, this includes enzymes (and cofactors, mRNA, genes) of the pheromone biosynthetic pathways, hormones (and genes) involved in controlling pheromone production, receptors and second messengers for the hormones, and host plant cues that control release of the hormone. In receiving ma...

  11. Advanced Manufacturing Technologies

    Science.gov (United States)

    Fikes, John

    2016-01-01

    Advanced Manufacturing Technologies (AMT) is developing and maturing innovative and advanced manufacturing technologies that will enable more capable and lower-cost spacecraft, launch vehicles and infrastructure to enable exploration missions. The technologies will utilize cutting edge materials and emerging capabilities including metallic processes, additive manufacturing, composites, and digital manufacturing. The AMT project supports the National Manufacturing Initiative involving collaboration with other government agencies.

  12. Performance of a pilot-scale biotrickling filter in controlling the volatile organic compound emissions in a furniture manufacturing facility.

    Science.gov (United States)

    Martínez-Soria, Vicente; Gabaldón, Carmen; Penya-Roja, Josep M; Palau, Jordi; Alvarez-Hornos, F Javier; Sempere, Feliu; Soriano, Carlos

    2009-08-01

    A 0.75-m3 pilot-scale biotrickling filter was run for over 1 yr in a Spanish furniture company to evaluate its performance in the removal of volatile organic compounds (VOCs) contained in the emission of two different paint spray booths. The first one was an open front booth used to manually paint furniture, and the second focus was an automatically operated closed booth operated to paint pieces of furniture. In both cases, the VOC emissions were very irregular, with rapid and extreme fluctuations. The pilot plant was operated at an empty bed residence time (EBRT) ranging from 10 to 40 sec, and good removal efficiencies of VOCs were usually obtained. When a buffering activated carbon prefilter was installed, the system performance was improved considerably, so a much better compliance with legal constraints was reached. After different shutdowns in the factory, the period to recover the previous performance of the biotrickling reactor was minimal. A weekend dehydration strategy was developed and implemented to control the pressure drop associated with excessive biomass accumulation. PMID:19728494

  13. Support given by the manufacturer

    International Nuclear Information System (INIS)

    As regards German NPP, the purchaser has the control function and the manufacturer the role of a general planner binding together all supply lots. Therefore the manufacturer possesses a very broad and thorough detailed knowledge of the plant functioning and becomes a life-long important partner of the plant. Such partnership requires from the manufacturer to provide continuously available and economical services to the plant; he must work purposefully in a quality-conscious and innovative way. This is his vision, and he will comply with it over the whole service life of the plant. The importance of services is illustrated by a large number of examples. (orig./DG)

  14. The effect of statistical analytical measurement variations on the plant control parameters and production costs in cement manufacturing – a case study

    Directory of Open Access Journals (Sweden)

    A. D. Love

    2010-01-01

    Full Text Available Raw materials used in cement manufacturing normally have varying chemical compositions and require regular analyses for plant control purposes. This is achieved by using several analytical instruments, such as XRF and ICP. The values obtained for the major elements Ca, Si, Fe and Al, are used to calculate the plant control parameters Lime Saturation Factor (LSF, Silica Ratio (SR and Alumina Modulus (AM. These plant control parameters are used to regulate the mixing and blending of various raw meal components and to operate the plant optimally. Any errors and large fluctuations in these plant parameters not only influence the quality of the cement produced, but also have a major effect on the cost of production of cement clinker through their influence on the energy consumption and residence time in the kiln. This paper looks at the role that statistical variances in the analytical measurements of the major elements Ca, Si, Fe and Al can have on the ultimate LSF, SR and AM values calculated from these measurements. The influence of too high and too low values of the LSF, SR and AM on clinker quality and energy consumption is discussed, and acceptable variances in these three parameters, based on plant experiences, are established. The effect of variances in the LSF, SR and AM parameters on the production costs is then analysed, and it is shown that variations of as large as 30% and as little as 5% can potentially occur. The LSF calculation incorporates most chemical elements and therefore is prone to the largest number of variations due to statistical variances in the analytical determinations of the chemical elements. Despite all these variations in LSF values they actually produced the smallest influence on the production cost of the clinker. It is therefore concluded that the LSF value is the most practical parameter for plant control purposes.

  15. A study on manufacturing and quality control technology of DUPIC fuel -A study on the direct use of spent PWR fuel in CANDU reactors-

    International Nuclear Information System (INIS)

    As the first year of the experimental research for the manufacturing and irradiation of prototypic DUPIC nuclear fuel, UO2 pellets made from the natural uranium dioxide were used for the study of OREOX (oxidation/reduction of oxide fuel) process. The reference oxidation and reduction processes were established from the evaluation of the characteristics of produced powders and pellets. The manufacturing process and the layout of the manufacturing equipment were established in consideration of the high radioactivity of DUPIC process and the function of hot cells. The properties of materials to be used for DUPIC manufacturing were evaluated, and the punching machine for decladding was also developed. (Author)

  16. Additive manufacturing : A new option in manufacturing

    OpenAIRE

    Nestrell, Annéa

    2015-01-01

    GE Healthcare wants to investigate whether additive manufacturing would be an alternative method in their workshops in the Umeå plant. Additive manufacturing is called 3D printing in everyday language and manufactures details by building them up layer by layer in an automated machine. The purpose of this work is therefore to investigate how mature additive manufacturing methods are and how they could be used at GE. The work has been divided into three parts. The first section investigates ho...

  17. Covalent chemistry in graphene electronics

    Directory of Open Access Journals (Sweden)

    Santanu Sarkar

    2012-06-01

    Full Text Available The development of selective high precision chemical functionalization strategies for device fabrication, in conjunction with associated techniques for patterning graphene wafers with atomic accuracy would provide the necessary basis for a post-CMOS manufacturing technology. This requires a thorough understanding of the principles governing the reactivity and patterning of graphene at the sub-nanometer length scale. This article reviews our quest to delineate the principles of graphene chemistry – that is, the chemistry at the Dirac point and beyond, and the effect of covalent chemistry on the electronic structure, electrical transport, and magnetic properties of this low-dimensional material in order to enable the scalable production of graphene-based devices for low- and high-end technology applications.

  18. 搅拌摩擦点焊机器人无纸化制造控制平台%Paperless Manufacturing Control Platform for Friction Stir Spot Welding Robot

    Institute of Scientific and Technical Information of China (English)

    王力; 乔凤斌; 陈正宇

    2013-01-01

      针对搅拌摩擦点焊机器人无纸化制造控制平台的实现方法进行了研究。采用STEP中性文件几何信息作为设计基础,根据对点焊机器人运动分析,利用OCC搭建了搅拌摩擦点焊机器人无纸化加工平台,以XML文件作为数控加工程序、监控与控制的数据载体。阐明了单个搅拌摩擦点焊机器人加工控制方法。同时,应用面向服务的网络控制框架方法,对搅拌摩擦点焊机器人组的远程控制与监控进行了研究与设计,使得搅拌摩擦点焊机器人焊接加工设计与控制过程更加简单。%The paperless manufacturing control platform realization method of robotic friction stir spot welding equipment has been aimed at and studied. By using geometrical information of STEP neutral file as a design basis,and according to movement analysis of the spot welding robot,the OCC was used to build a friction stir spot welding robot platform for paperless processing. Also the Extensible Markup Language (XML)file was used as the Computer Numerical Control (CNC)machining process monitoring and control data carrier. The single process control method of robotic friction stir spot welding equipment was illustrated. At the same time,by applying the method of serviceoriented network control framework,the remote control and monitor of friction stir spot welding robotic group was also studied and designed. It has made even simple of the design and control process of welding by the friction stir spot welding robot.

  19. Desktop Manufacturing Technologies.

    Science.gov (United States)

    Snyder, Mark

    1991-01-01

    Desktop manufacturing is the use of data from a computer-assisted design system to construct actual models of an object. Emerging processes are stereolithography, laser sintering, ballistic particle manufacturing, laminated object manufacturing, and photochemical machining. (SK)

  20. Peroxy radical chemistry and the control of ozone photochemistry at Mace Head, Ireland during the summer of 2002

    Directory of Open Access Journals (Sweden)

    Z. L. Fleming

    2006-01-01

    Full Text Available Peroxy radical (HO2+ΣRO2 measurements, using the PEroxy Radical Chemical Amplification (PERCA technique at the North Atlantic Marine Boundary Layer EXperiment (NAMBLEX at Mace Head in summer 2002, are presented and put into the context of marine, boundary-layer chemistry. A suite of other chemical parameters (NO, NO2, NO3, CO, CH4, O3, VOCs, peroxides, photolysis frequencies and meteorological measurements, are used to present a detailed analysis of the role of peroxy radicals in tropospheric oxidation cycles and ozone formation. Under the range of conditions encountered the peroxy radical daily maxima varied from 10 to 40 pptv. The diurnal cycles showed an asymmetric shape typically shifted to the afternoon. Using a box model based on the master chemical mechanism the average model measurement agreement was 2.5 across the campaign. The addition of halogen oxides to the model increases the level of model/measurement agreement, apparently by respeciation of HOx. A good correlation exists between j(HCHO.[HCHO] and the peroxy radicals indicative of the importance of HCHO in the remote atmosphere as a HOx source, particularly in the afternoon. The peroxy radicals showed a strong dependence on [NO2] with a break point at 0.1 ppbv, where the radicals increased concomitantly with the reactive VOC loading, this is a lower value than seen at representative urban campaigns. The HO2/(HO2+ΣRO2 ratios are dependent on [NOx] ranging between 0.2 and 0.6, with the ratio increasing linearly with NOx. Significant night-time levels of peroxy radicals were measured up to 25 pptv. The contribution of ozone-alkenes and NO3-alkene chemistry to night-time peroxy radical production was shown to be on average 59 and 41%. The campaign mean net ozone production rate was 0.11±0.3 ppbv h-1. The ozone production rate was strongly dependent on [NO] having linear sensitivity (dln(P(O3/dln(NO=1.0. The results imply that the N(O3 (the in-situ net photochemical rate of ozone

  1. Statistical and Computational Techniques in Manufacturing

    CERN Document Server

    2012-01-01

    In recent years, interest in developing statistical and computational techniques for applied manufacturing engineering has been increased. Today, due to the great complexity of manufacturing engineering and the high number of parameters used, conventional approaches are no longer sufficient. Therefore, in manufacturing, statistical and computational techniques have achieved several applications, namely, modelling and simulation manufacturing processes, optimization manufacturing parameters, monitoring and control, computer-aided process planning, etc. The present book aims to provide recent information on statistical and computational techniques applied in manufacturing engineering. The content is suitable for final undergraduate engineering courses or as a subject on manufacturing at the postgraduate level. This book serves as a useful reference for academics, statistical and computational science researchers, mechanical, manufacturing and industrial engineers, and professionals in industries related to manu...

  2. Tribology in Manufacturing Technology

    CERN Document Server

    2013-01-01

    The present book aims to provide research advances on tribology in manufacturing technology for modern industry. This book can be used as a research book for final undergraduate engineering course (for example, mechanical, manufacturing, materials, etc) or as a subject on manufacturing at the postgraduate level. Also, this book can serve as a useful reference for academics, manufacturing and tribology researchers, mechanical, mechanical, manufacturing and materials engineers, professionals in related industries with manufacturing and tribology.

  3. Fine chemistry

    International Nuclear Information System (INIS)

    The 1988 progress report of the Fine Chemistry laboratory (Polytechnic School, France) is presented. The research programs are centered on the renewal of the organic chemistry most important reactions and on the invention of new, highly efficient and highly selective reactions, by applying low cost reagents and solvents. An important research domain concerns the study and fabrication of new catalysts. They are obtained by means of the reactive sputtering of the metals and metal oxydes thin films. The Monte Carlo simulations of the long-range electrostatic interaction in a clay and the obtention of acrylamides from anhydrous or acrylic ester are summarized. Moreover, the results obtained in the field of catalysis are also given. The published papers and the congress communications are included

  4. Revitalizing chemistry laboratory instruction

    Science.gov (United States)

    McBride, Phil Blake

    This dissertation involves research in three major domains of chemical education as partial fulfillment of the requirements for the Ph.D. program in chemistry at Miami University with a major emphasis on chemical education, and concurrent study in organic chemistry. Unit I, Development and Assessment of a Column Chromatography Laboratory Activity, addresses the domain of Instructional Materials Development and Testing. This unit outlines the process of developing a publishable laboratory activity, testing and revising that activity, and subsequently sharing that activity with the chemical education community. A laboratory activity focusing on the separation of methylene blue and sodium fluorescein was developed to demonstrate the effects of both the stationary and mobile phase in conducting a separation. Unit II, Bringing Industry to the Laboratory, addresses the domain of Curriculum Development and Testing. This unit outlines the development of the Chemistry of Copper Mining module, which is intended for use in high school or undergraduate college chemistry. The module uses the learning cycle approach to present the chemistry of the industrial processes of mining copper to the students. The module includes thirteen investigations (three of which are web-based and ten which are laboratory experiments) and an accompanying interactive CD-ROM, which provides an explanation of the chemistry used in copper mining with a virtual tour of an operational copper mine. Unit III, An Alternative Method of Teaching Chemistry. Integrating Lecture and the Laboratory, is a project that addresses the domain of Research in Student Learning. Fundamental Chemistry was taught at Eastern Arizona College as an integrated lecture/laboratory course that met in two-hour blocks on Monday, Wednesday, and Friday. The students taking this integrated course were compared with students taking the traditional 1-hour lectures held on Monday, Wednesday, and Friday, with accompanying 3-hour lab on

  5. Organometallic chemistry

    OpenAIRE

    Bashkin, James K.; M.L.H. Green; Dr. M. L. H. Green

    1982-01-01

    Transition metal organometallic chemistry is a rapidly expanding field, which has an important relationship to industrial problems of petrochemical catalysis. This thesis describes studies of fundamental organometallic reaction processes, such as C-H and C-C bond formation and cleavage, and investigations of the structure and bonding of organometallic compounds. A number of techniques were used to pursue these studies, including synthesis, X-ray crystallography, and semi-em...

  6. Interstellar chemistry

    OpenAIRE

    Klemperer, William

    2006-01-01

    In the past half century, radioastronomy has changed our perception and understanding of the universe. In this issue of PNAS, the molecular chemistry directly observed within the galaxy is discussed. For the most part, the description of the molecular transformations requires specific kinetic schemes rather than chemical thermodynamics. Ionization of the very abundant molecular hydrogen and atomic helium followed by their secondary reactions is discussed. The rich variety of organic species o...

  7. Analytical chemistry

    International Nuclear Information System (INIS)

    The division for Analytical Chemistry continued to try and develope an accurate method for the separation of trace amounts from mixtures which, contain various other elements. Ion exchange chromatography is of special importance in this regard. New separation techniques were tried on certain trace amounts in South African standard rock materials and special ceramics. Methods were also tested for the separation of carrier-free radioisotopes from irradiated cyclotron discs

  8. Computational chemistry

    Science.gov (United States)

    Arnold, J. O.

    1987-01-01

    With the advent of supercomputers, modern computational chemistry algorithms and codes, a powerful tool was created to help fill NASA's continuing need for information on the properties of matter in hostile or unusual environments. Computational resources provided under the National Aerodynamics Simulator (NAS) program were a cornerstone for recent advancements in this field. Properties of gases, materials, and their interactions can be determined from solutions of the governing equations. In the case of gases, for example, radiative transition probabilites per particle, bond-dissociation energies, and rates of simple chemical reactions can be determined computationally as reliably as from experiment. The data are proving to be quite valuable in providing inputs to real-gas flow simulation codes used to compute aerothermodynamic loads on NASA's aeroassist orbital transfer vehicles and a host of problems related to the National Aerospace Plane Program. Although more approximate, similar solutions can be obtained for ensembles of atoms simulating small particles of materials with and without the presence of gases. Computational chemistry has application in studying catalysis, properties of polymers, all of interest to various NASA missions, including those previously mentioned. In addition to discussing these applications of computational chemistry within NASA, the governing equations and the need for supercomputers for their solution is outlined.

  9. Green chemistry

    International Nuclear Information System (INIS)

    A grand challenge facing government, industry, and academia in the relationship of our technological society to the environment is reinventing the use of materials. To address this challenge, collaboration from an interdisciplinary group of stakeholders will be necessary. Traditionally, the approach to risk management of materials and chemicals has been through inerventions intended to reduce exposure to materials that are hazardous to health and the environment. In 1990, the Pollution Prevention Act encouraged a new tact-elimination of hazards at the source. An emerging approach to this grand challenge seeks to embed the diverse set of environmental perspectives and interests in the everyday practice of the people most responsible for using and creating new materials--chemists. The approach, which has come to be known as Green Chemistry, intends to eliminate intrinsic hazard itself, rather than focusing on reducing risk by minimizing exposure. This chapter addresses the representation of downstream environmental stakeholder interests in the upstream everyday practice that is reinventing chemistry and its material inputs, products, and waste as described in the '12 Principles of Green Chemistry'

  10. PWR secondary water chemistry guidelines: Revision 3

    International Nuclear Information System (INIS)

    An effective, state-of-the art secondary water chemistry control program is essential to maximize the availability and operating life of major PWR components. Furthermore, the costs related to maintaining secondary water chemistry will likely be less than the repair or replacement of steam generators or large turbine rotors, with resulting outages taken into account. The revised PWR secondary water chemistry guidelines in this report represent the latest field and laboratory data on steam generator corrosion phenomena. This document supersedes Interim PWR Secondary Water Chemistry Recommendations for IGA/SCC Control (EPRI report TR-101230) as well as PWR Secondary Water Chemistry Guidelines--Revision 2 (NP-6239)

  11. Digital manufacturing-the development direction of the manufacturing technology in the 21st century

    Institute of Scientific and Technical Information of China (English)

    XIONG You-lun; YIN Zhou-ping

    2006-01-01

    After introducing the concepts of digital manufacturing technology,the discipline framework of digital manufacturing is presented in the paper by discussing its basic concept,theory foundation,key technology and scientific problems in detail.As the core of the advanced manufacturing technology,digital manufacturing is gradually becoming the main manufacturing technology of the twenty-first century.Firstly,the main features of digital manufacturing are indicated and its key supporting technologies are investigated by grouping them into four levels related to product development, numerical control, production management,and enterprise collaboration,respectively.Moreover,the existing problems in the research on the multi-discipline theory foundation of digital manufacturing such as manufacturing informatics, computational manufacturing,and manufacturing intelligence,are also indicated.Then,the core scientific problems of digital manufacturing are discussed in depth,which focuses on digitization of manufacturing information,modeling of manufacturing constraints,high-speed and high-precision numerical control theory,and Internet-based collaboration and integration.Lastly, the development trends and application perspectives of digital manufacturing are concluded.

  12. Guideline for Evaluating Analytical Chemistry Capabilities and Recommending Upgraded Methods and Instrumentation for Nuclear Material Control and Accountability at Russian Nuclear Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Russ, G.P.

    1999-10-21

    Analytical chemistry plays a key role in nuclear material control and accounting (MC and A). A large part of Special Nuclear Material (SNM) inventories and virtually all of the highly attractive SNM inventories are based on sampling bulk materials followed by destructive assay (DA) of these materials. These measurements support MC and A in process control, physical inventory verification, evaluation of the effects of process changes, detecting and resolving shipper-receiver differences, and the resolution of inspector-facility differences. When evaluating these important functions, US Project Teams need to carefully assess the existing Russian analytical chemistry capabilities and to specify appropriate upgrades where needed. This evaluation and the specification of upgrades have proven difficult, in part, because of the highly specialized and technical nature of DA and because of the wide variety of methods and applications. In addition, providing a DA capability to a Russian analytical laboratory requires much more than simply supplying new instrumentation. Experience has shown that DA upgrades at Russian analytical facilities require more support equipment than was originally anticipated by US Teams. The purpose of this guidance document is to: (1) recommend criteria for US Projects Teams to use in their evaluation of Russian DA capabilities; (2) provide a basis for selection of appropriate upgrades where capabilities are inadequate to support MC and A goals; and (3) to provide a list of Da methods suitable for MC and A with the following information: performance and applications information, strengths and limitations, and references and information on cost. Criteria for evaluating existing capabilities and determining appropriate upgrades are difficult to define. However, this is the basic information needed by the US project Teams. Section IV addresses these criteria.

  13. Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and NO donors: insights into listeriocidal activity of oxidative and nitrosative stress.

    Science.gov (United States)

    Ogawa, R; Pacelli, R; Espey, M G; Miranda, K M; Friedman, N; Kim, S M; Cox, G; Mitchell, J B; Wink, D A; Russo, A

    2001-02-01

    The physiological function of nitric oxide (NO) in the defense against pathogens is multifaceted. The exact chemistry by which NO combats intracellular pathogens such as Listeria monocytogenes is yet unresolved. We examined the effects of NO exposure, either delivered by NO donors or generated in situ within ANA-1 murine macrophages, on L. monocytogenes growth. Production of NO by the two NONOate compounds PAPA/NO (NH2(C3H6)(N[N(O)NO]C3H7) and DEA/NO (Na(C2H5)2N[N(O)NO]) resulted in L. monocytogenes cytostasis with minimal cytotoxicity. Reactive oxygen species generated from xanthine oxidase/hypoxanthine were neither bactericidal nor cytostatic and did not alter the action of NO. L. monocytogenes growth was also suppressed upon internalization into ANA-1 murine macrophages primed with interferon-gamma (INF-gamma) + tumor necrosis factor-alpha (TNF-alpha or INF-gamma + lipid polysaccharide (LPS). Growth suppression correlated with nitrite formation and nitrosation of 2,3-diaminonaphthalene elicited by stimulated murine macrophages. This nitrosative chemistry was not dependent upon nor mediated by interaction with reactive oxygen species (ROS), but resulted solely from NO and intermediates related to nitrosative stress. The role of nitrosation in controlling L. monocytogenes was further examined by monitoring the effects of exposure to NO on an important virulence factor, Listeriolysin O, which was inhibited under nitrosative conditions. These results suggest that nitrosative stress mediated by macrophages is an important component of the immunological arsenal in controlling L. monocytogenes infections. PMID:11165873

  14. Guideline for Evaluating Analytical Chemistry Capabilities and Recommending Upgraded Methods and Instrumentation for Nuclear Material Control and Accountability at Russian Nuclear Facilities

    International Nuclear Information System (INIS)

    Analytical chemistry plays a key role in nuclear material control and accounting (MC and A). A large part of Special Nuclear Material (SNM) inventories and virtually all of the highly attractive SNM inventories are based on sampling bulk materials followed by destructive assay (DA) of these materials. These measurements support MC and A in process control, physical inventory verification, evaluation of the effects of process changes, detecting and resolving shipper-receiver differences, and the resolution of inspector-facility differences. When evaluating these important functions, US Project Teams need to carefully assess the existing Russian analytical chemistry capabilities and to specify appropriate upgrades where needed. This evaluation and the specification of upgrades have proven difficult, in part, because of the highly specialized and technical nature of DA and because of the wide variety of methods and applications. In addition, providing a DA capability to a Russian analytical laboratory requires much more than simply supplying new instrumentation. Experience has shown that DA upgrades at Russian analytical facilities require more support equipment than was originally anticipated by US Teams. The purpose of this guidance document is to: (1) recommend criteria for US Projects Teams to use in their evaluation of Russian DA capabilities; (2) provide a basis for selection of appropriate upgrades where capabilities are inadequate to support MC and A goals; and (3) to provide a list of Da methods suitable for MC and A with the following information: performance and applications information, strengths and limitations, and references and information on cost. Criteria for evaluating existing capabilities and determining appropriate upgrades are difficult to define. However, this is the basic information needed by the US project Teams. Section IV addresses these criteria

  15. Evaluation of the applicability of amines as feed-water control reagents in terms of equilibrium water chemistry

    International Nuclear Information System (INIS)

    All Volatile Treatment (AVT), using ammonia and hydrazine, has been employed in Japan to control the pH of PWR secondary water. However, this treatment may become less effective at high temperatures. In recent years, new methods for controlling pH values have been studied overseas. One such method in high-pH control, which employs high-concentration ammonia solution. Other methods involve treatment with organic chemicals such as ethanolamine (ETA) and dimethylamine (DMA). It is important to evaluate the pH control effects of these new treatments. The purpose of this study was to evaluate the effect of these treatments on pH control and on mitigation of iron and copper oxides transportation into a PWR secondary water system. The main results are as follows: 1. High-pH control treatment can decrease the transportation of iron oxide in both feed-water and drainage-water systems. However, it is necessary to exclude copper alloys and to devise methods for decreasing the condensate demineralizer load. 2. ETA treatment appears to be more effective in mitigating the transportation of iron and copper oxides than the conventional AVT treatment. ETA treatment is the most effective method for pH control, particularly in drainage-water system. (author)

  16. Peroxy radical chemistry and the control of ozone photochemistry at Mace Head, Ireland during the summer of 2002

    Directory of Open Access Journals (Sweden)

    Z. L. Fleming

    2005-11-01

    Full Text Available Peroxy radical (HO2+ΣRO2 measurements, using the PEroxy Radical Chemical Amplification (PERCA technique at the North Atlantic Marine Boundary Layer EXperiment (NAMBLEX at Mace Head in summer 2002, are presented and put into the context of marine, boundary-layer chemistry. A suite of other chemical parameters (NO, NO2, NO3, CO, CH4, O3, VOCs, peroxides, photolysis frequencies and meteorological measurements, are used to present a detailed analysis of the role of peroxy radicals in tropospheric oxidation cycles and ozone formation. Under the range of conditions encountered the peroxy radical daily maxima varied from 10 to 40 pptv. The diurnal cycles showed an asymmetric shape typically shifted to the afternoon. Using a box model based on the master chemical mechanism the average model measurement agreement was 2.5 across the campaign. The addition of halogen oxides to the model increases the level of model/measurement agreement, apparently by respeciation of HOx. A good correlation exists between j(HCHO.[HCHO] and the peroxy radicals indicative of the importance of HCHO in the remote atmosphere as a HOx source, particularly in the afternoon. The peroxy radicals showed a strong dependence on [NOx] with a break point at 0.1 ppbv, where the radicals increased concomitantly with the reactive VOC loading, this is a lower value than seen at representative urban campaigns. The HO2/(HO2+ΣRO2 ratios are dependent on [NOx] ranging between 0.2 and 0.6, with the ratio increasing linearly with NOx. Significant night-time levels of peroxy radicals were measured up to 25 pptv. The contribution of ozone-alkenes and NO3-alkene chemistry to night-time peroxy radical production was shown to be on average 59 and 41%. The campaign mean net ozone production rate was 0.11±0.3 ppbv h−1

  17. Beryllium chemistry and processing

    CERN Document Server

    Walsh, Kenneth A

    2009-01-01

    This book introduces beryllium; its history, its chemical, mechanical, and physical properties including nuclear properties. The 29 chapters include the mineralogy of beryllium and the preferred global sources of ore bodies. The identification and specifics of the industrial metallurgical processes used to form oxide from the ore and then metal from the oxide are thoroughly described. The special features of beryllium chemistry are introduced, including analytical chemical practices. Beryllium compounds of industrial interest are identified and discussed. Alloying, casting, powder processing, forming, metal removal, joining and other manufacturing processes are covered. The effect of composition and process on the mechanical and physical properties of beryllium alloys assists the reader in material selection. The physical metallurgy chapter brings conformity between chemical and physical metallurgical processing of beryllium, metal, alloys, and compounds. The environmental degradation of beryllium and its all...

  18. Scheduling By Using Fuzzy Logic in Manufacturing

    Directory of Open Access Journals (Sweden)

    Miss. Ashwini. A. Mate

    2014-07-01

    Full Text Available This paper represents the scheduling process in furniture manufacturing unit. It gives the fuzzy logic application in flexible manufacturing system. Flexible manufacturing systems are production system in furniture manufacturing unit. FMS consist of same multipurpose numerically controlled machines. Here in this project the scheduling has been done in FMS by using fuzzy logic tool in Matlab software. The fuzzy logic based scheduling model in this paper will deals with the job and best alternative route selection with multi-criteria of machine. Here two criteria for job and sequencing and routing with rules. This model is applicable to the scheduling of any manufacturing industry.

  19. Biogeochemical processes in a clay formation in situ experiment: Part E - Equilibrium controls on chemistry of pore water from the Opalinus Clay, Mont Terri Underground Research Laboratory, Switzerland

    International Nuclear Information System (INIS)

    Highlights: → Equilibrium models of water-rock reactions in clay rocks are reviewed. → Analyses of pore waters of the Opalinus Clay from boreholes in the Mont Terri URL, Switzerland, are tabulated. → Results of modelling with various mineral controls are compared with the analyses. → Best agreement results with calcite, dolomite and siderite or daphnite saturation, Na-K-Ca-Mg exchange and/or kaolinite, illite, quartz and celestite saturation. → This approach allows calculation of the chemistry of pore water in clays too impermeable to yield water samples. - Abstract: The chemistry of pore water (particularly pH and ionic strength) is an important property of clay rocks being considered as host rocks for long-term storage of radioactive waste. Pore waters in clay-rich rocks generally cannot be sampled directly. Instead, their chemistry must be found using laboratory-measured properties of core samples and geochemical modelling. Many such measurements have been made on samples from the Opalinus Clay from the Mont Terri Underground Research Laboratory (URL). Several boreholes in that URL yielded water samples against which pore water models have been calibrated. Following a first synthesis report published in 2003, this paper presents the evolution of the modelling approaches developed within Mont Terri URL scientific programs through the last decade (1997-2009). Models are compared to the composition of waters sampled during dedicated borehole experiments. Reanalysis of the models, parameters and database enabled the principal shortcomings of the previous modelling efforts to be overcome. The inability to model the K concentrations correctly with the measured cation exchange properties was found to be due to the use of an inappropriate selectivity coefficient for Na-K exchange; the inability to reproduce the measured carbonate chemistry and pH of the pore waters using mineral-water reactions alone was corrected by considering clay mineral equilibria. Re

  20. Biogeochemical processes in a clay formation in situ experiment: Part E - Equilibrium controls on chemistry of pore water from the Opalinus Clay, Mont Terri Underground Research Laboratory, Switzerland

    Energy Technology Data Exchange (ETDEWEB)

    Pearson, F.J., E-mail: fjpearson@gmail.com [Ground-Water Geochemistry, 5108 Trent Woods Dr., New Bern, NC 28562 (United States); Tournassat, Christophe; Gaucher, Eric C. [BRGM, B.P. 36009, 45060 Orleans Cedex 2 (France)

    2011-06-15

    Highlights: > Equilibrium models of water-rock reactions in clay rocks are reviewed. > Analyses of pore waters of the Opalinus Clay from boreholes in the Mont Terri URL, Switzerland, are tabulated. > Results of modelling with various mineral controls are compared with the analyses. > Best agreement results with calcite, dolomite and siderite or daphnite saturation, Na-K-Ca-Mg exchange and/or kaolinite, illite, quartz and celestite saturation. > This approach allows calculation of the chemistry of pore water in clays too impermeable to yield water samples. - Abstract: The chemistry of pore water (particularly pH and ionic strength) is an important property of clay rocks being considered as host rocks for long-term storage of radioactive waste. Pore waters in clay-rich rocks generally cannot be sampled directly. Instead, their chemistry must be found using laboratory-measured properties of core samples and geochemical modelling. Many such measurements have been made on samples from the Opalinus Clay from the Mont Terri Underground Research Laboratory (URL). Several boreholes in that URL yielded water samples against which pore water models have been calibrated. Following a first synthesis report published in 2003, this paper presents the evolution of the modelling approaches developed within Mont Terri URL scientific programs through the last decade (1997-2009). Models are compared to the composition of waters sampled during dedicated borehole experiments. Reanalysis of the models, parameters and database enabled the principal shortcomings of the previous modelling efforts to be overcome. The inability to model the K concentrations correctly with the measured cation exchange properties was found to be due to the use of an inappropriate selectivity coefficient for Na-K exchange; the inability to reproduce the measured carbonate chemistry and pH of the pore waters using mineral-water reactions alone was corrected by considering clay mineral equilibria. Re