Sample records for chemical warfare

  1. Chemical warfare in freshwater

    NARCIS (Netherlands)

    Mulderij, Gabi


    Aquatic macrophytes can excrete chemical substances into their enviroment and these compounds may inhibit the growth of phytoplankton. This process is defined as allelopathy: one organism has effects on another via the excretion of a (mixture of) chemical substance(s). With laboratory and field expe

  2. Chemical profiling of chemical warfare agents for forensic purposes

    NARCIS (Netherlands)

    Noort, D.; Reuver, L.P.J. de; Fidder, A.; Tromp, M.; Verschraagen, M.


    A program has been initiated towards the chemical profiling of chemical warfare agents, in order to support forensic investigations towards synthesis routes, production sites and suspect chemical suppliers. Within the first stage of the project various chemical warfare agents (VX, sulfur mustard, sa

  3. Handbook of toxicology of chemical warfare agents

    CERN Document Server


    This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book. This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and wildlife, biosensors, biomarkers, on-site and laboratory analytical methods, decontamination and detoxification procedures, prophylactic, therapeutic and countermeasures, and the role of homeland security. Presents a comprehensive look at all aspects of chemical warfare toxicology in one reference work. This saves research...

  4. Environmental chemistry of chemical warfare agents

    Energy Technology Data Exchange (ETDEWEB)

    MacNaughton, M.G.; Brewer, J.H.; Ledbetter-Ferrill, J. [Southwest Research Inst., San Antonio, TX (United States)


    This paper summarizes the approach used in the preparation of a Handbook for the Corps of Engineers, Huntsville Division, on the environmental chemistry of chemical warfare agents. The agents GB and HD will be used to illustrate the type of information in the report. Those readers interested in the full report should contact Mr. Arkie Fanning, Huntsville Corps of Engineers at (505) 955-5256. The U.S. Army Corps of Engineers (ACE) has identified approximately 7,200 formerly used defense sites (FUDS) in the United States, some of which are suspected to be contaminated with chemical warfare agents (CWA). The ACE has responsibility for environmental clean-up of FUDS, including site characterization, evaluation and remediation of the site. Thirty-four FUDS and 48 active DOD installations that may contain CWA were identified in an Interim Survey and Analysis Report by the USACMDA Program Manager for Non-Stockpile Chemical Material (NSCM). The chemical agents listed include sulfur mustard (H), lewisite (L), tabun (GA), sarin (GB), VX, hydrogen cyanide (AC), cyanogen chloride (CK), phosgene (CG), BZ, and CS.

  5. [Decontamination of chemical and biological warfare agents]. (United States)

    Seto, Yasuo


    Chemical and biological warfare agents (CBWA's) are diverse in nature; volatile acute low-molecular-weight toxic compounds, chemical warfare agents (CWA's, gaseous choking and blood agents, volatile nerve gases and blister agents, nonvolatile vomit agents and lacrymators), biological toxins (nonvolatile low-molecular-weight toxins, proteinous toxins) and microbes (bacteria, viruses, rickettsiae). In the consequence management against chemical and biological terrorism, speedy decontamination of victims, facilities and equipment is required for the minimization of the damage. In the present situation, washing victims and contaminated materials with large volumes of water is the basic way, and additionally hypochlorite salt solution is used for decomposition of CWA's. However, it still remains unsolved how to dispose large volumes of waste water, and the decontamination reagents have serious limitation of high toxicity, despoiling nature against the environments, long finishing time and non-durability in effective decontamination. Namely, the existing decontamination system is not effective, nonspecifically affecting the surrounding non-target materials. Therefore, it is the urgent matter to build up the usable decontamination system surpassing the present technologies. The symposiast presents the on-going joint project of research and development of the novel decontamination system against CBWA's, in the purpose of realizing nontoxic, fast, specific, effective and economical terrorism on-site decontamination. The projects consists of (1) establishment of the decontamination evaluation methods and verification of the existing technologies and adaptation of bacterial organophosphorus hydrolase, (2) development of adsorptive elimination technologies using molecular recognition tools, and (4) development of deactivation technologies using photocatalysis.

  6. Chemical Warfare Agent Degradation and Decontamination

    Energy Technology Data Exchange (ETDEWEB)

    Talmage, Sylvia Smith [ORNL; Watson, Annetta Paule [ORNL; Hauschild, Veronique [U.S. Environmental Protection Agency; Munro, Nancy B [ORNL; King, J. [U.S. Army Environmental Center


    The decontamination of chemical warfare agents (CWA) from structures, environmental media, and even personnel has become an area of particular interest in recent years due to increased homeland security concerns. In addition to terrorist attacks, scenarios such as accidental releases of CWA from U.S. stockpile sites or from historic, buried munitions are also subjects for response planning. To facilitate rapid identification of practical and effective decontamination approaches, this paper reviews pathways of CWA degradation by natural means as well as those resulting from deliberately applied solutions and technologies; these pathways and technologies are compared and contrasted. We then review various technologies, both traditional and recent, with some emphasis on decontamination materials used for surfaces that are difficult to clean. Discussion is limited to the major threat CWA, namely sulfur mustard (HD, bis(2-chloroethyl)sulfide), VX (O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothioate), and the G-series nerve agents. The principal G-agents are GA (tabun, ethyl N,N-dimethylphosphoramidocyanidate), GB (sarin, isopropyl methylphosphonofluoridate), and GD (soman, pinacolyl methylphosphonofluoridate). The chemical decontamination pathways of each agent are outlined, with some discussion of intermediate and final degradation product toxicity. In all cases, and regardless of the CWA degradation pathway chosen for decontamination, it will be necessary to collect and analyze pertinent environmental samples during the treatment phase to confirm attainment of clearance levels.

  7. Integrated Assessment Systems for Chemical Warfare Material

    Energy Technology Data Exchange (ETDEWEB)

    A. M. Snyder; D. A. Verrill; G. L. Thinnes; K. D. Watts; R. J. McMorland


    The US Army must respond to a variety of situations involving suspect discovered, recovered, stored, and buried chemical warfare materiel (CWM). In some cases, the identity of the fill materiel and the status of the fusing and firing train cannot be visually determined due to aging of the container, or because the item is contained in an over-pack. In these cases, non-intrusive assessments are required to provide information to allow safe handling, storage, and disposal of the materiel. This paper will provide an overview of the integrated mobile and facility-based CWM assessment system prototypes that have been, and are being developed, at the Idaho National Engineering and Environmental Laboratory (INEEL) for the US Army Non-Stockpile Chemical Materiel Project. In addition, this paper will discuss advanced sensors being developed to enhance the capability of the existing and future assessment systems. The Phase I Mobile Munitions Assessment System (MMAS) is currently being used by the Army's Technical Escort Unit (TEU) at Dugway Proving Ground, Utah. This system includes equipment for non-intrusively identifying the munitions fill materiel and for assessing the condition and stability of the fuzes, firing trains, and other potential safety hazards. The system provides a self-contained, integrated command post including an on-board computer system, communications equipment, video and photographic equipment, weather monitoring equipment, and miscellaneous safety-related equipment. The Phase II MMAS is currently being tested and qualified for use by the INEEL and the US Army. The Phase II system contains several new assessment systems that significantly enhance the ability to assess CWM. A facility-based munitions assessment system prototype is being developed for the assessment of CWM stored in igloos at Pine Bluff Arsenal, Arkansas. This system is currently in the design and fabrication stages. Numerous CWM advanced sensors are being developed and tested, and

  8. Environmental assessments of sea dumped chemical warfare agents

    DEFF Research Database (Denmark)

    Sanderson, Hans; Fauser, Patrik

    This is a report on the information gathered during work related to sea dumped chemical warfare agents. It mainly reviews the work conducted in relation to the installation of the two Nord Stream gas pipeline from 2008-2012. The focus was on the weight-of-evidence risk assessment of disturbed CWA...

  9. Cutaneous reactions in nuclear, biological and chemical warfare

    Directory of Open Access Journals (Sweden)

    Arora Sandeep


    Full Text Available Nuclear, biological and chemical warfare have in recent times been responsible for an increasing number of otherwise rare dermatoses. Many nations are now maintaining overt and clandestine stockpiles of such arsenal. With increasing terrorist threats, these agents of mass destruction pose a risk to the civilian population. Nuclear and chemical attacks manifest immediately while biological attacks manifest later. Chemical and biological attacks pose a significant risk to the attending medical personnel. The large scale of anticipated casualties in the event of such an occurrence would need the expertise of all physicians, including dermatologists, both military and civilian. Dermatologists are uniquely qualified in this respect. This article aims at presenting a review of the cutaneous manifestations in nuclear, chemical and biological warfare and their management.

  10. Carbon Nanotubes: Detection of Chemical and Biological Warfare Agents

    Directory of Open Access Journals (Sweden)

    Om Kumar


    Full Text Available Discovery of carbon nanotubes has great impact on the development of newer methodologies and devicesuseful for the analysis of various types of chemicals. The functionalisation of CNTs with biomolecules relatedto chemical and biological warfare agents makes these useful for the detection of these agents. The detectionsensitivity can be increased manyfold. Various types of chemical and biological sensors were developed usingvarious type of carbon nanotubes as well as nano particles of different metals.Defence Science Journal, 2008, 58(5, pp.617-625, DOI:

  11. Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  12. Chemical and biological warfare: General studies. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning federally sponsored and conducted studies into chemical and biological warfare operations and planning. These studies cover areas not addressed in other parts of this series. The topics include production and storage of agents, delivery techniques, training, military and civil defense, general planning studies, psychological reactions to chemical warfare, evaluations of materials exposed to chemical agents, and studies on banning or limiting chemical warfare. Other published searches in this series on chemical warfare cover detection and warning, defoliants, protection, and biological studies, including chemistry and toxicology.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  13. Status of dental health in chemical warfare victims: The case of Isfahan, Iran

    Directory of Open Access Journals (Sweden)

    Ahmad Mottaghi


    Conclusion: Chemical warfare victims have relatively poor dental/oral health. Chemical injury might cause a dysfunction in saliva secretion, with decrease in saliva secretion increasing the risk for tooth decay and periodontal disorders. Further research is required to find out the exact underlying mechanisms and the factors associated with poor dental/oral health in chemical warfare victims.

  14. Ultraviolet Raman scattering from persistent chemical warfare agents (United States)

    Kullander, Fredrik; Wästerby, Pär.; Landström, Lars


    Laser induced Raman scattering at excitation wavelengths in the middle ultraviolet was examined using a pulsed tunable laser based spectrometer system. Droplets of chemical warfare agents, with a volume of 2 μl, were placed on a silicon surface and irradiated with sequences of laser pulses. The Raman scattering from V-series nerve agents, Tabun (GA) and Mustard gas (HD) was studied with the aim of finding the optimum parameters and the requirements for a detection system. A particular emphasis was put on V-agents that have been previously shown to yield relatively weak Raman scattering in this excitation band.

  15. The development of immunoassays for detection of chemical warfare agents

    Energy Technology Data Exchange (ETDEWEB)

    Lenz, D.E. [Army Medical Research Inst. of Chemical Defense, Aberdeen Proving Ground, MD (United States)


    With the advent of enzyme linked immunoabsorbant assays (ELISA) and monoclonal antibodies in the last two decades, there has been considerable effort devoted to the development of antibodies to detect and quantify low molecular weight toxic substances in environmental or biological fluids. Polyclonal antibodies against paraoxon (the toxic metabolite of parathion) were reported as capable of detecting paraoxon in body fluids at a level of 10{sup -9} M ({approximately}260 pg/mL) when used in a competitive inhibition enzyme immunoassay (CIEIA). Monoclonal antibodies developed against a structural analogue of the chemical warfare agent soman were capable of detecting soman in buffer solutions at a level of 10{sup -6} M ({approximately}180 ng/mL). In addition, these antibodies were highly specific for soman even in the presence of its major hydrolysis product. Subsequent studies with antisoman monoclonal antibodies reported an extension of the level of sensitivity to -80 ng/mL. Furthermore these antibodies did not cross react with other chemical warfare nerve agents such as sarin or tabun. In all cases, the time for a confirmatory test was two hours or less. Immunoassays for T-2 micotoxins have also been reported with a minimal detection range of 2 pg/assay to 50 ng/assay for the polyclonal and monoclonal T-2 antibodies respectively. These antibodies offer a sensitive, rapid and low cost approach to the diagnosis or detection of the presence of toxic chemical substances.

  16. Antidotes and treatments for chemical warfare/terrorism agents: an evidence-based review. (United States)

    Rodgers, G C; Condurache, C T


    This article reviews the evidence supporting the efficacy of antidotes used or recommended for the potential chemical warfare agents of most concern. Chemical warfare agents considered include cyanide, vesicants, pulmonary irritants such as chlorine and phosgene, and nerve agents. The strength of evidence for most antidotes is weak, highlighting the need for additional research in this area.

  17. Looming Threat of Chemical and Biological Warfare Agents

    Directory of Open Access Journals (Sweden)

    A.K. Goel


    Full Text Available In the recent past, a dramatic shift has been observed in the strategies of warfare from conventional to non-conventional. Now-a-days, traditional power is of less importance than it used to be earlier. Weapons of mass destruction, which comprise of nuclear weapons, and chemical and biological warfare agents, are posing a great peril to the world due to their devastating potential. Though, there are several bilateral as well as multilateral treaties to control the use and proliferation of these weapons, yet the risk of use of such agents by non-state actors cannot be overlooked. Chances of use of chemical and biological agents are more likely than the nuclear weapons. A comparison of nuclear, chemical and biological weapons in terms of technology, cost, signature, effectiveness on protected and un-protected troops shows that chemical and biological weapon programmes require much lower level of technology and cost than the nuclear weapon programme. Further, there is no or least distinctive and readily observable signature in biological weapon programme in comparison to nuclear and chemical weapon facilities. There can be two possibilities of use of these agents in terrorist attacks. First, there is a risk of transfer of material or know-how of these weapons to terrorists for using against the adversaries and second, the risk of these agents being pilfered due to poor security, thereby sabotaging the national security. The International Committee of Red Cross in February 1918 reckoned these agents as ‘barbarous inventions’ that can ‘only be called criminal’.

  18. LIDAR for Detection of Chemical and Biological Warfare Agents

    Directory of Open Access Journals (Sweden)

    S Veerabuthiran


    Full Text Available Remote detection of chemical and biological warfare agents and toxic gases in the atmosphere is of current interest to both the military and civilian agencies. Out of all currently available techniques, no single technique provides efficient detection against such threats at significant standoff distances. Light detection and ranging (LIDAR technologies, based on the transmission of laser pulses and analysis of the return signals, have demonstrated impressive capabilities in remote detection of such toxic chemicals. LIDAR is a highly sensitive tool to detect the extremely low concentrations of various toxic agents present in the form of thin clouds at distances of few kilometer. The detection of these toxic clouds is based on the approach of first detecting and measuring the range of the clouds using the scattering phenomena and subsequently identifying the composition of toxic clouds using absorption and fluorescence phenomena. Laser Science and Technology Centre (LASTEC, Delhi has been working on the design and development of LIDAR systems for detection of chemical and biological warfare (CBW agents. In this paper, theoretical analysis of differential absorption LIDAR (DIAL for detection of chemical agents and fluorescence LIDAR for detection of biological agents has been discussed. For some typical parametric conditions, the received power levels from different ranges to detect specific concentrations of chemical or biological clouds have been computed and discussed. The technical details of the indigenously developed backscattering LIDAR, which detects and measures the distance of cloud layers up to 5 km is also presented.Defence Science Journal, 2011, 61(3, pp.241-250, DOI:

  19. The development of immunoassays for detection of chemical warfare agents

    Energy Technology Data Exchange (ETDEWEB)

    Lenz, D.E.; Brimfield, A.A.; Cook, L. [Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD (United States)


    With the advent of enzyme linked immunoabsorbent assays (ELISA) and monoclonal antibodies in the last two decades, there has been considerable effort devoted to the development of antibodies to detect and quantify low molecular weight toxic substances in environmental or biological fluids. Polyclonal antibodies against paraoxon (the toxic metabolite of parathion) were capable of detecting paraoxon in body fluids at a level of 10{sup -9} M ({approximately}260 pg/mL) when used in a competitive inhibition enzyme immunoassay (CIEIA). Monoclonal antibodies developed against a structural analogue of the chemical warfare agent soman were capable of detection soman in buffer solutions at a level of 10{sup -6} M ({approximately}180 ng/mL). In addition these antibodies were found to be highly specific for soman even in the presence of its major hydrolysis product. Subsequent studies with antisoman monoclonal antibodies extended the level of sensitivity to {approximately}80 ng/mL. Furthermore these antibodies did not cross react with other chemical warfare nerve agents such as sarin or tabun. In all cases, the time for a confirmatory test was two hours or less. Immunoassays for T-2 micotoxins have also been reported with a minimal detection range of 2 pg/assay to 50 ng/assay for the polyclonal and monoclonal T-2 antibodies respectively. These reagents offer a sensitive, rapid and low cost approach to the diagnosis or detection of the presence of toxic chemical substances. More recent efforts have focussed on developing antibodies specific for sulfur mustard a highly reactive vesicating agent.

  20. Respiratory Protection Against Chemical and Biological Warfare Agents

    Directory of Open Access Journals (Sweden)

    G.K. Prasad


    Full Text Available Chemical and biological warfare (CBW agents pose unavoidable threat, both to soldiers and civilians.Exposure to such deadly agents amidst the CBW agents contaminated environment can be avoided bytaking proper protective measures. Respiratory protection is indispensable when the soldiers or civiliansare surrounded by such deadly environment as contamination-free air is needed for respiration purposes.In this context, an attempt has been made to review the literature for the past five decades on developmentof various protective devices for respiratory protection against aerosols, gases, and vapours of CBWagents. This review covers structural, textural, and adsorption properties of materials used in gas filtersand mechanical filters for the removal of CBW agents.Defence Science Journal, 2008, 58(5, pp.686-697, DOI:

  1. Methodology and biological monitoring of exposure to chemical warfare agents

    Energy Technology Data Exchange (ETDEWEB)

    Shih, M.L.; Smith, J.R.; McMonagle, J.D. [Army Medical Research Inst. of Chemical Defense, Aberdeen Proving Ground, MD (United States)


    In the past few years, our institute has developed several GC/MS methods for the detection of the breakdown products of toxic organophosphonates (soman, sarin, GF) and vesicant sulfur mustard in biological samples. Recently we developed a modified GC/MS method for VX and are continually working on the methodology for lewisite and tabun. The purpose is to have an analytical tool to verify the exposure of chemical warfare agents in humans. Analytical procedures for quantitating the hydrolyzed phosphonic acids from nerve agents in environmental samples have been reported by many analysts. For more complex matrices such as biological samples, there is not yet a method reported. To make these polar acids amenable to gas chromatographic analysis a prior derivatization is needed. We found the pentafluorobenzyl ester derivatives of the phosphonates are suitable for verification and pharmacokinetic studies in biological samples. This method may also serve as an alternative method for confirmation purposes in environmental samples.

  2. Estimated Chemical Warfare Agent Surface Clearance Goals for Remediation Pre-Planning

    Energy Technology Data Exchange (ETDEWEB)

    Dolislager, Frederick [University of Tennessee, Knoxville (UTK); Bansleben, Dr. Donald [U.S. Department of Homeland Security; Watson, Annetta Paule [ORNL


    Health-based surface clearance goals, in units of mg/cm2, have been developed for the persistent chemical warfare agents sulfur mustard (HD) and nerve agent VX as well as their principal degradation products. Selection of model parameters and critical receptor (toddler child) allow calculation of surface residue estimates protective for the toddler child, the general population and adult employees of a facilty that has undergone chemical warfare agent attack.

  3. Prevalence of Asthma in Children of Chemical Warfare Victims (United States)

    Mirsadraee, Majid; Mozaffari, Abolfazl; Attaran, Davood


    Objective Exposure of DNA to sulfur mustard gas may increase the inheritance of asthma in chemical warfare victims' (CWV) offspring. The objective of this study was to determine the prevalence of asthma in children of CWV and compare it to asthmatic children in the general population. Methods Four hundred and nine children from 130 CWV fathers and 440 children from 145 asthmatic parents from two cities in Iran participated in this study. The prevalence of asthma was determined by standard questionnaire released for epidemiological survey of asthma in children and compared between two groups. Findings The prevalence of asthma in the CWV group was 15%; this was not significantly different from the control group (12.5%). The children of the CWV group reported a significantly greater incidence of wheezing (1.2±3.1 attacks) per year, but the control group reported more severe attacks leading to speech difficulties (3%) and coughing (7%). Regression analysis showed that with increasing family size in the control group, the number of subjects suffering from asthmatic symptoms decreases significantly (r=0.86, P=0.001). Conclusion Chemical agents may increase the prevalence of asthma in the offspring of CWV. PMID:23056804

  4. Fate of chemical warfare agents and toxic indutrial chemicals in landfills

    DEFF Research Database (Denmark)

    Bartelt-Hunt, D.L.; Barlaz, M.A.; Knappe, D.R.U.


    One component of preparedness for a chemical attack is planning for the disposal of contaminated debris. To assess the feasibility of contaminated debris disposal in municipal solid waste (MSW) landfills, the fate of selected chemical warfare agents (CWAs) and toxic industrial chemicals (TICs......) in MSW landfills was predicted with a mathematical model. Five blister agents [sulfur mustard (HD), nitrogen mustard (HN-2), lewisite (L), ethyldichloroarsine (ED), and phosgene oxime (CX)], eight nerve agents [tabun (GA), sarin (GB), soman (GD), GE, GF, VX, VG, and VM], one riot-control agent [CS...

  5. Human scalp permeability to the chemical warfare agent VX. (United States)

    Rolland, P; Bolzinger, M-A; Cruz, C; Briançon, S; Josse, D


    The use of chemical warfare agents such as VX in terrorism act might lead to contamination of the civilian population. Human scalp decontamination may require appropriate products and procedures. Due to ethical reasons, skin decontamination studies usually involve in vitro skin models, but human scalp skin samples are uncommon and expensive. The purpose of this study was to characterize the in vitro permeability to VX of human scalp, and to compare it with (a) human abdominal skin, and (b) pig skin from two different anatomic sites: ear and skull roof, in order to design a relevant model. Based on the VX skin permeation kinetics and distribution, we demonstrated that (a) human scalp was significantly more permeable to VX than abdominal skin and (b) pig-ear skin was the most relevant model to predict the in vitro human scalp permeability. Our results indicated that the follicular pathway significantly contributed to the skin absorption of VX through human scalp. In addition, the hair follicles and the stratum corneum significantly contributed to the formation of a skin reservoir for VX.

  6. Blaptica dubia as sentinels for exposure to chemical warfare agents - a pilot study. (United States)

    Worek, Franz; Seeger, Thomas; Neumaier, Katharina; Wille, Timo; Thiermann, Horst


    The increased interest of terrorist groups in toxic chemicals and chemical warfare agents presents a continuing threat to our societies. Early warning and detection is a key component for effective countermeasures against such deadly agents. Presently available and near term solutions have a number of major drawbacks, e.g. lack of automated, remote warning and detection of primarily low volatile chemical warfare agents. An alternative approach is the use of animals as sentinels for exposure to toxic chemicals. To overcome disadvantages of vertebrates the present pilot study was initiated to investigate the suitability of South American cockroaches (Blaptica dubia) as warning system for exposure to chemical warfare nerve and blister agents. Initial in vitro experiments with nerve agents showed an increasing inhibitory potency in the order tabun - cyclosarin - sarin - soman - VX of cockroach cholinesterase. Exposure of cockroaches to chemical warfare agents resulted in clearly visible and reproducible reactions, the onset being dependent on the agent and dose. With nerve agents the onset was related to the volatility of the agents. The blister agent lewisite induced signs largely comparable to those of nerve agents while sulfur mustard exposed animals exhibited a different sequence of events. In conclusion, this first pilot study indicates that Blaptica dubia could serve as a warning system to exposure of chemical warfare agents. A cockroach-based system will not detect or identify a particular chemical warfare agent but could trigger further actions, e.g. specific detection and increased protective status. By designing appropriate boxes with (IR) motion sensors and remote control (IR) camera automated off-site warning systems could be realized.

  7. Key Planning Factors for Recovery from a Chemical Warfare Agent Incident (United States)


    chemical scenario involving the release of a blister agent (mustard lewisite) would result in a waste that the State of Colorado would regulate as... Waste Management ................................................................. 24 4.3 Key Planning Factors: Recovery Planning...Planning Factors, this document presents a chemical warfare agent scenario featuring Agent Yellow, a blister agent. Agent Yellow is a mixture of

  8. Treatability study report for remediation of chemical warfare agent contaminated soils using peroxysulfate ex-situ treatment. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Pugh, J.R.; Grinstead, J.H.; Farley, J.A.; Enlow, P.D.; Kelly, D.A.


    This laboratory scale study examines the feasibility of using peroxysulfate based oxidants to remediate soils contaminated with GB, Hi, and VX. The project was conducted with chemical warfare agent simulants. The study concludes that peroxysulfates, and particularly peroxydisulfate, can degrade chemical warfare agent simulants in soil and recommends continuing research.


    Energy Technology Data Exchange (ETDEWEB)

    T. R. Twomey; A. J. Caffrey; D. L. Chichester


    Prompt gamma-ray neutron activation analysis (PGNAA) is now a proven method for the identification of chemical warfare agents and explosives in military projectiles and storage containers. Idaho National Laboratory is developing a next-generation PGNAA instrument based on the new Ortec Detective mechanically-cooled HPGe detector and a neutron generator. In this paper we review PGNAA analysis of suspect chemical warfare munitions, and we discuss the advantages and disadvantages of replacing the californium-252 radioisotopic neutron source with a compact accelerator neutron generator.

  10. Reactive skin decontamination lotion (RSDL) for the decontamination of chemical warfare agent (CWA) dermal exposure. (United States)

    Schwartz, M D; Hurst, C G; Kirk, M A; Reedy, S J D; Braue, E H


    Rapid decontamination of the skin is the single most important action to prevent dermal absorption of chemical contaminants in persons exposed to chemical warfare agents (CWA) and toxic industrial chemicals (TICs) as a result of accidental or intentional release. Chemicals on the skin may be removed by mechanical means through the use of dry sorbents or water. Recent interest in decontamination systems which both partition contaminants away from the skin and actively neutralize the chemical has led to the development of several reactive decontamination solutions. This article will review the recently FDA-approved Reactive Skin Decontamination Lotion (RSDL) and will summarize the toxicity and efficacy studies conducted to date. Evidence of RSDL's superior performance against vesicant and organophosphorus chemical warfare agents compared to water, bleach, and dry sorbents, suggests that RSDL may have a role in mass human exposure chemical decontamination in both the military and civilian arenas.

  11. Rapid Ultrasensitive Chemical-Fingerprint Detection of Chemical and Biochemical Warfare Agents

    Energy Technology Data Exchange (ETDEWEB)



    Vibrational spectra can serve as chemical fingerprints for positive identification of chemical and biological warfare molecules. The required speed and sensitivity might be achieved with surface-enhanced Raman spectroscopy (SERS) using nanotextured metal surfaces. Systematic and reproducible methods for preparing metallic surfaces that maximize sensitivity have not been previously developed. This work sought to develop methods for forming high-efficiency metallic nanostructures that can be integrated with either gas or liquid-phase chem-lab-on-a-chip separation columns to provide a highly sensitive, highly selective microanalytical system for detecting current and future chem/bio agents. In addition, improved protein microchromatographic systems have been made by the creation of acrylate-based porous polymer monoliths that can serve as protein preconcentrators to reduce the optical system sensitivity required to detect and identify a particular protein, such as a bacterial toxin.

  12. Disruption of a binary organogel by the chemical warfare agent soman (GD) and common organophosphorus simulants


    Hiscock, Jennifer R.; Sambrook, Mark R; Ede, Jayne A.; Wells, Neil J.; Philip A. Gale


    The chemical warfare agent (CWA) soman (GD) acts as a molecular stimulus for the disruption of an anthracene-based binary organogel prepared in cyclohexane. The CWA simulants dimethyl methylphosphonate (DMMP) and diethyl chlorophosphate (DCP) were also found to disrupt the binary organogel through changes in solvent polarity and reactions with the gelator.\\ud \\ud

  13. On modeling of the evaporation of chemical warfare agents on the ground

    NARCIS (Netherlands)

    Westin, S.N.; Winter, S.; Karlsson, E.; Hin, A.; Oeseburg, F.


    A model for evaporation of chemical warfare agents on the ground has been developed. The process of evaporation is described in three steps: (1) the immediate drop enlargement due to impact momentum is modeled using an empirical correlation from technical literature; (2) further enlargement caused b

  14. Investigating Iraq’s Chemical Warfare Program: Updated and Expanded Research Plan (United States)


    chemical warfare, chemical weapons, Conflict Records Research Center, Tabun , Sarin, UN Sepcial Commission, UN UN Monitoring, Verification and Inspection...7 for tabun and sarin; and Ahmed 2 & 3 for production of precursors for tabun and sarin. The general contractor is Al Fao General Establishment that... tabun , and sarin. “mid- 1970s” Al Hazen Institute has by this time set up contacts with “30 major foreign organizations and companies” for securing

  15. Quality of life in chemical warfare survivors with ophthalmologic injuries: the first results form Iran Chemical Warfare Victims Health Assessment Study

    Directory of Open Access Journals (Sweden)

    Soroush Mohammad


    Full Text Available Abstract Background Iraq used chemical weapons extensively against the Iranians during the Iran-Iraq war (1980–1988. The aim of this study was to assess the health related quality of life (HRQOL in people who had ophthalmologic complications due to the sulfur mustard gas exposure during the war. Methods The Veterans and Martyrs Affair Foundation (VMAF database indicated that there were 196 patients with severe ophthalmologic complications due to chemical weapons exposure. Of these, those who gave consent (n = 147 entered into the study. Quality of life was measured using the 36-item Short Form Health Survey (SF-36 and scores were compared to those of the general public. In addition logistic regression analysis was performed to indicate variables that contribute to physical and mental health related quality of life. Results The mean age of the patients was 44.8 (SD = 8.7 ranging from 21 to 75 years. About one-third of the cases (n= 50 reported exposure to chemical weapons more than once. The mean exposure duration to sulfur mustard gas was 21.6 years (SD = 1.2. The lowest scores on the SF-36 subscales were found to be: the role physical and the general health. Quality of life in chemical warfare victims who had ophthalmologic problems was significantly lower than the general public (P Conclusion The study findings suggest that chemical warfare victims with ophthalmologic complications suffer from poor health related quality of life. It seems that the need for provision of health and support for this population is urgent. In addition, further research is necessary to measure health related quality of life in victims with different types of disabilities in order to support and enhance quality of life among this population.

  16. Fate of chemical warfare agents and toxic industrial chemicals in landfills. (United States)

    Bartelt-Hunt, Shannon L; Barlaz, Morton A; Knappe, Detlef R U; Kjeldsen, Peter


    One component of preparedness for a chemical attack is planning for the disposal of contaminated debris. To assess the feasibility of contaminated debris disposal in municipal solid waste (MSW) landfills, the fate of selected chemical warfare agents (CWAs) and toxic industrial chemicals (TICs) in MSW landfills was predicted with a mathematical model. Five blister agents [sulfur mustard (HD), nitrogen mustard (HN-2), lewisite (L), ethyldichloroarsine (ED), and phosgene oxime (CX)], eight nerve agents [tabun (GA), sarin (GB), soman (GD), GE, GF, VX, VG, and VM], one riot-control agent [CS], and two TICs [furan and carbon disulfide] were studied. The effects of both infiltration (climate) and contaminant biodegradability on fate predictions were assessed. Model results showed that hydrolysis and gas-phase advection were the principal fate pathways for CWAs and TICs, respectively. Apart from CX and the TICs, none of the investigated compounds was predicted to persist in a landfill for more than 5 years. Climate had little impact on CWA/TIC fate, and biodegradability was only important for compounds with long hydrolysis half-lives. Monte Carlo simulations were performed to assess the influence of uncertainty in model input parameters on CWA/TIC fate predictions. Correlation analyses showed that uncertainty in hydrolysis rate constants was the primary contributor to variance of CWA fate predictions, while uncertainty in the Henry's Law constant and landfill gas-production rate accounted for most of the variance of TIC fate predictions. CWA hydrolysates were more persistent than the parent CWAs, but limited information is available on abiotic or biotic transformation rates for these chemicals.

  17. Mass spectrometric analysis of chemical warfare agents in support of a chemical terrorist event

    Energy Technology Data Exchange (ETDEWEB)

    Hancock, J.R.; D' Agostino, P.A.; Chenier, C.L. [Defence R and D Canada Suffield, Medicine Hat, AB (Canada)


    Chemical warfare (CW) agents are considered to be any chemicals which, through their chemical action on life processes can cause death, temporary incapacitation or permanent harm to humans or animals. In Canada, the probability of a CW terrorist attack is low despite the catastrophic consequences that would result from such an attack. The three levels of government would be responding to such an event. CW agent response training for all levels of government is offered at Defence R and D Canada-Suffield. Appropriate samples must be collected for analysis in a laboratory, as such an event would lead to a criminal investigation. Research into new methods for the identification of CW agents is being conducted by the analytical laboratory at Defence R and D Canada-Suffield. Gas chromatography and mass spectrometry (GC-MS) are being used extensively to separate and characterize CW agents in organic extracts. In the case of aqueous samples, another method might be more appropriate, since additional sample handling is required before GC-MS analysis can be performed. Minimal sample handling is required when using liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) for direct analysis of CW agents. The authors demonstrated the use of LC-ESI-MS for analyzing CW agents and their hydrolysis products in aqueous samples. For the analysis of nerve agents and phosphonic acids in soil, comparable or superior results to organic extraction and GC-MS were obtained for aqueous extractions followed by LC-ESI-MS. The combination of GC-MS and LC-ESI-MS for the analysis of mustard related compounds in soil extracts from a former mustard storage area showed that the two methods are complementary in this situation. 9 refs., 3 tabs., 5 figs.

  18. Ultrahigh Vacuum Studies of the Fundamental Interactions of Chemical Warfare Agents and Their Simulants with Amorphous Silica (United States)


    G. The Dissociative Adsorptoin of N2 on a Multiply Promoted Iron Catalyst Used for Ammonia Synthesis : A Temperature Programmed Desorption Study...where their potential use as chemical warfare agents began. The synthesis of other G-series agents, G standing for German, shortly followed. Also...warfare. The most common blister agent, sulfur mustard, was first synthesized in 1822 by Despretz. Victor Meyer developed a modified synthesis to

  19. Chemical warfare in freshwater. Allelpathic effects of macrophytes on phytoplankton

    NARCIS (Netherlands)

    Mulderij, G.


    Aquatic macrophytes can excrete chemical substances into their enviroment and these compounds may inhibit the growth of phytoplankton. This process is defined as allelopathy: one organism has effects on another via the excretion of a (mixture of) chemical substance(s). With laboratory and field expe

  20. Chemical warfare and medical response during World War I. (United States)

    Fitzgerald, Gerard J


    The first large-scale use of a traditional weapon of mass destruction (chemical, biological, or nuclear) involved the successful deployment of chemical weapons during World War I (1914-1918). Historians now refer to the Great War as the chemist's war because of the scientific and engineering mobilization efforts by the major belligerents. The development, production, and deployment of war gases such as chlorine, phosgene, and mustard created a new and complex public health threat that endangered not only soldiers and civilians on the battlefield but also chemical workers on the home front involved in the large-scale manufacturing processes. The story of chemical weapons research and development during that war provides useful insights for current public health practitioners faced with a possible chemical weapons attack against civilian or military populations.

  1. Chemical and biological warfare: Biology, chemistry, and toxicology. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning the physiological effects, physicochemical effects, and toxicology of chemical and biological warfare agents. Citations discuss toxic chemicals, chemical agent simulants, detoxification and decontamination, environmental toxicity, and land pollution. Detection techniques and warning systems are examined in a separate bibliography. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  2. Chemical and biological warfare: Biology, chemistry, and toxicology. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning the physiological effects, physicochemical effects, and toxicology of chemical and biological warfare agents. Citations discuss toxic chemicals, chemical agent simulants, detoxification and decontamination, environmental toxicity, and land pollution. Detection techniques and warning systems are examined in a separate bibliography. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  3. Collaborative Core Research Program for Chemical-Biological Warfare Defense (United States)


    Research Center (UC-DDRC, part of UC-MDI). Using an EvoTec robot , single point (10 μM final solution test chemical concentration) 2 measurements...assay on neuroblastoma cell lines. We performed this method, as well as incorporated a novel method developed at US Army Medical Research Institute of...formulations chemists to determine the optimal dose methods. These new CWA countermeasures will be transitioned to the Chemical Biological Medical Systems for

  4. Next Generation Non-particulate Dry Nonwoven Pad for Chemical Warfare Agent Decontamination

    Energy Technology Data Exchange (ETDEWEB)

    Ramkumar, S S; Love, A; Sata, U R; Koester, C J; Smith, W J; Keating, G A; Hobbs, L; Cox, S B; Lagna, W M; Kendall, R J


    New, non-particulate decontamination materials promise to reduce both military and civilian casualties by enabling individuals to decontaminate themselves and their equipment within minutes of exposure to chemical warfare agents or other toxic materials. One of the most promising new materials has been developed using a needlepunching nonwoven process to construct a novel and non-particulate composite fabric of multiple layers, including an inner layer of activated carbon fabric, which is well-suited for the decontamination of both personnel and equipment. This paper describes the development of a composite nonwoven pad and compares efficacy test results for this pad with results from testing other decontamination systems. The efficacy of the dry nonwoven fabric pad was demonstrated specifically for decontamination of the chemical warfare blister agent bis(2-chloroethyl)sulfide (H or sulfur mustard). GC/MS results indicate that the composite fabric was capable of significantly reducing the vapor hazard from mustard liquid absorbed into the nonwoven dry fabric pad. The mustard adsorption efficiency of the nonwoven pad was significantly higher than particulate activated carbon (p=0.041) and was similar to the currently fielded US military M291 kit (p=0.952). The nonwoven pad has several advantages over other materials, especially its non-particulate, yet flexible, construction. This composite fabric was also shown to be chemically compatible with potential toxic and hazardous liquids, which span a range of hydrophilic and hydrophobic chemicals, including a concentrated acid, an organic solvent and a mild oxidant, bleach.

  5. Modeling Warfare in Social Animals: A "Chemical" Approach (United States)

    Santarlasci, Alisa; Martelloni, Gianluca; Frizzi, Filippo; Santini, Giacomo; Bagnoli, Franco


    We present here a general method for modelling the dynamics of battles among social animals. The proposed method exploits the procedures widely used to model chemical reactions, but still uncommon in behavioural studies. We applied this methodology to the interpretation of experimental observations of battles between two species of ants (Lasius neglectus and Lasius paralienus), but this scheme may have a wider applicability and can be extended to other species as well. We performed two types of experiment labelled as interaction and mortality. The interaction experiments are designed to obtain information on the combat dynamics and lasted one hour. The mortality ones provide information on the casualty rates of the two species and lasted five hours. We modelled the interactions among ants using a chemical model which considers the single ant individuals and fighting groups analogously to atoms and molecules. The mean-field behaviour of the model is described by a set of non-linear differential equations. We also performed stochastic simulations of the corresponding agent-based model by means of the Gillespie event-driven integration scheme. By fitting the stochastic trajectories with the deterministic model, we obtained the probability distribution of the reaction parameters. The main result that we obtained is a dominance phase diagram, that gives the average trajectory of a generic battle, for an arbitrary number of opponents. This phase diagram was validated with some extra experiments. With respect to other war models (e.g., Lanchester's ones), our chemical model considers all phases of the battle and not only casualties. This allows a more detailed description of the battle (with a larger number of parameters), allowing the development of more sophisticated models (e.g., spatial ones), with the goal of distinguishing collective effects from the strategic ones. PMID:25369269

  6. Development of Bicarbonate-Activated Peroxide as a Chemical and Biological Warfare Agent Decontaminant (United States)


    Peroxide (HOO-) 7.8 29 26.7 ± 0.2 t-Butyl hydroperoxide ((CH3)3COO-) 7.8 9.7 39 Cumene hydroperoxide ((C6H6)C(CH3)2OO-) 7.8 9.3 22 All reactions run with...peroxymonocarbonate ion (HCO4-) as the oxidant in the catalytic oxidation reactions . For perhydrolytic cleavage of organophosphates the peroxycarbonate dianion...solubility and reaction rates for applications in chemical warfare agent decontamination. -O *C O O OH -O *C OH O HO *C OH O *CO2 HO2 - H2OHO *C O O OH pKa

  7. Chemical and biological warfare: Detection and warning systems. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning the detection, identification, verification, and warning systems of chemical and biological warfare agents. Citations discuss agents sampling, monitoring, and assessment. Techniques include chromotography, biosensing, chemical analysis, and DNA probes. Land pollution, soil tests, and skin protection are examined. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  8. APSTNG: neutron interrogation for detection of explosives, drugs, and nuclear and chemical warfare materials (United States)

    Rhodes, Edgar A.; Peters, Charles W.


    A recently developed neutron diagnostic probe system has the potential to satisfy a significant number of van-mobile and fixed-portal requirements for nondestructive detection, including monitoring of contraband explosives, drugs, and weapon materials, and treaty verification of sealed munitions. The probe is based on a unique associated-particle sealed-tube neutron generator (APSTNG) that interrogates the object of interest with a low-intensity beam of 14- MeV neutrons generated from the deuterium-tritium reaction and that detects the alpha-particle associated with each neutron. Gamma-ray spectra of resulting neutron reactions identify nuclides associated with all major chemicals in explosives, drugs, and chemical warfare agents, as well as many pollutants and fissile and fertile special nuclear material. Flight times determined from detection times of the gamma-rays and alpha-particles yield a separate coarse tomographic image of each identified nuclide. The APSTNG also forms the basis for a compact fast-neutron transmission imaging system that can be used along with or instead of the emission imaging system. Proof-of-concept experiments have been performed under laboratory conditions for simulated nuclear and chemical warfare munitions and for explosives and drugs. The small and relatively inexpensive APSTNG exhibits high reliability and can be quickly replaced. Surveillance systems based on APSTNG technology can avoid the large physical size, high capital and operating expenses, and reliability problems associated with complex accelerators.

  9. Reevaluation of 1999 Health-Based Environmental Screening Levels (HBESLs) for Chemical Warfare Agents

    Energy Technology Data Exchange (ETDEWEB)

    Watson, Annetta Paule [ORNL; Dolislager, Fredrick G [ORNL


    This report evaluates whether new information and updated scientific models require that changes be made to previously published health-based environmental soil screening levels (HBESLs) and associated environmental fate/breakdown information for chemical warfare agents (USACHPPM 1999). Specifically, the present evaluation describes and compares changes that have been made since 1999 to U.S. Environmental Protection Agency (EPA) risk assessment models, EPA exposure assumptions, as well as to specific chemical warfare agent parameters (e.g., toxicity values). Comparison was made between screening value estimates recalculated with current assumptions and earlier health-based environmental screening levels presented in 1999. The chemical warfare agents evaluated include the G-series and VX nerve agents and the vesicants sulfur mustard (agent HD) and Lewisite (agent L). In addition, key degradation products of these agents were also evaluated. Study findings indicate that the combined effect of updates and/or changes to EPA risk models, EPA default exposure parameters, and certain chemical warfare agent toxicity criteria does not result in significant alteration to the USACHPPM (1999) health-based environmental screening level estimates for the G-series and VX nerve agents or the vesicant agents HD and L. Given that EPA's final position on separate Tier 1 screening levels for indoor and outdoor worker screening assessments has not yet been released as of May 2007, the study authors find that the 1999 screening level estimates (see Table ES.1) are still appropriate and protective for screening residential as well as nonresidential sites. As such, risk management decisions made on the basis of USACHPPM (1999) recommendations do not require reconsideration. While the 1999 HBESL values are appropriate for continued use as general screening criteria, the updated '2007' estimates (presented below) that follow the new EPA protocols currently under development

  10. Possible Long Term Effects of Chemical Warfare Using Visual Evoked Potentials

    Directory of Open Access Journals (Sweden)

    Abbas Riazi


    Full Text Available Some studies have already addressed the effects of occupational organic solvent exposure on the visually evoked potentials (VEPs. Visual system is an important target for Sulphur Mustard (SM toxicity. A number of Iranian victims of Sulphur Mustard (SM agent were apprehensive about the delay effect of SM on their vision and a possible delay effect of SM on their visual cortex. This investigation was performed on 34 individuals with a history of chemical exposure and a control group of 15 normal people. The Toennies electro-diagnosis device was used and its signals were saved as the latencies. The mean of N75, N140 and P100 of victims of chemical warfare (VCWs and control group indicated no significant results (P>0.05. The VCWs did not show any visual symptoms and there was no clear deficit in their VEPs.

  11. Investigation of Acute Toxicity of a Chemical Warfare Agent in Kidneys

    Directory of Open Access Journals (Sweden)

    Turgut Topal


    Full Text Available One of the most important chemical warfare agents, sulfur mustard (SM causes crucial acute and chronic toxic effects. Lung, skin, eye and kidneys are the most affected organs. In this work, it was investigated if increased nitric oxide (NO and peroxynitrite are involved in nitrogen mustard (NM induced kidney damage. In this experimen, aminoguanidine (AG as inducible nitric oxide synthase (iNOS inhibitor and ebselen as peroxynitrite scavenger were used. NM administration resulted in important oxidant and antioxidant changes as well as tissue damage in kidneys. Therapeutic agents showed significant protection and reduced oxidant parameteres leading to tissue healing was observed. Results of this study suggest that drugs with similar properties can be used to protect kidney damage caused by NM. [TAF Prev Med Bull. 2007; 6(4: 227-232

  12. Investigation of Acute Toxicity of a Chemical Warfare Agent in Kidneys

    Directory of Open Access Journals (Sweden)

    Turgut Topal


    Full Text Available One of the most important chemical warfare agents, sulfur mustard (SM causes crucial acute and chronic toxic effects. Lung, skin, eye and kidneys are the most affected organs. In this work, it was investigated if increased nitric oxide (NO and peroxynitrite are involved in nitrogen mustard (NM induced kidney damage. In this experimen, aminoguanidine (AG as inducible nitric oxide synthase (iNOS inhibitor and ebselen as peroxynitrite scavenger were used. NM administration resulted in important oxidant and antioxidant changes as well as tissue damage in kidneys. Therapeutic agents showed significant protection and reduced oxidant parameteres leading to tissue healing was observed. Results of this study suggest that drugs with similar properties can be used to protect kidney damage caused by NM. [TAF Prev Med Bull 2007; 6(4.000: 227-232

  13. Decontamination of adsorbed chemical warfare agents on activated carbon using hydrogen peroxide solutions. (United States)

    Osovsky, Ruth; Kaplan, Doron; Nir, Ido; Rotter, Hadar; Elisha, Shmuel; Columbus, Ishay


    Mild treatment with hydrogen peroxide solutions (3-30%) efficiently decomposes adsorbed chemical warfare agents (CWAs) on microporous activated carbons used in protective garments and air filters. Better than 95% decomposition of adsorbed sulfur mustard (HD), sarin, and VX was achieved at ambient temperatures within 1-24 h, depending on the H2O2 concentration. HD was oxidized to the nontoxic HD-sulfoxide. The nerve agents were perhydrolyzed to the respective nontoxic methylphosphonic acids. The relative rapidity of the oxidation and perhydrolysis under these conditions is attributed to the microenvironment of the micropores. Apparently, the reactions are favored due to basic sites on the carbon surface. Our findings suggest a potential environmentally friendly route for decontamination of adsorbed CWAs, using H2O2 without the need of cosolvents or activators.

  14. Chemical and Biological Warfare: Should Rapid Detection Techniques Be Researched To Dissuade Usage? A Review

    Directory of Open Access Journals (Sweden)

    Mark R. Hurst


    Full Text Available Chemistry, microbiology and genetic engineering have opened new doorways for the human race to propel itself to a better future. However, there is a darker side to Bioengineering. One element of this is the manufacture and proliferation of biological and chemical weapons. It is clearly in the interest of humankind to prevent the future use of such weapons of mass destruction. Though many agents have been proposed as potential biological and chemical weapons, the feasibility of these weapons is a matter of conjecture. The unpredictable and indiscriminate devastation caused by natural epidemics and hazardous chemicals during wartime without medical treatment should warn humans of the dangers of employing them as weapons. This study argues rapid detection techniques may dissuade future use. Many agents are far less toxic to treatment. A quick response time to most attacks will decrease the chances of serious health issues. The agent will be less effective and discourage the attacker from using the weapon. Fortunately, the Chemical and Biological Weapons Convention (CWCIBWC allows defensive work in the area of biological and chemical weapons. Consequently, the review will discuss history, delivery/dispersal systems and specific agents of the warfare. The study presents current developments in biosensors for toxic materials of defense interest. It concludes with future directions for biosensor development.

  15. Chemical and biological warfare: Protection, decontamination, and disposal. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning the means to defend against chemical and biological agents used in military operations, and to eliminate the effects of such agents on personnel, equipment, and grounds. Protection is accomplished through protective clothing and masks, and in buildings and shelters through filtration. Elimination of effects includes decontamination and removal of the agents from clothing, equipment, buildings, grounds, and water, using chemical deactivation, incineration, and controlled disposal of material in injection wells and ocean dumping. Other Published Searches in this series cover chemical warfare detection; defoliants; general studies; biochemistry and therapy; and biology, chemistry, and toxicology associated with chemical warfare agents.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  16. Chemical and biological warfare: Protection, decontamination, and disposal. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning the means to defend against chemical and biological agents used in military operations, and to eliminate the effects of such agents on personnel, equipment, and grounds. Protection is accomplished through protective clothing and masks, and in buildings and shelters through filtration. Elimination of effects includes decontamination and removal of the agents from clothing, equipment, buildings, grounds, and water, using chemical deactivation, incineration, and controlled disposal of material in injection wells and ocean dumping. Other Published Searches in this series cover chemical warfare detection; defoliants; general studies; biochemistry and therapy; and biology, chemistry, and toxicology associated with chemical warfare agents. (Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  17. Research on the Interaction of Hydrogen-Bond Acidic Polymer Sensitive Sensor Materials with Chemical Warfare Agents Simulants by Inverse Gas Chromatography


    Liu Yang; Qiang Han; Shuya Cao; Feng Huang; Molin Qin; Chenghai Guo; Mingyu Ding


    Hydrogen-bond acidic polymers are important high affinity materials sensitive to organophosphates in the chemical warfare agent sensor detection process. Interactions between the sensor sensitive materials and chemical warfare agent simulants were studied by inverse gas chromatography. Hydrogen bonded acidic polymers, i.e., BSP3, were prepared for micro-packed columns to examine the interaction. DMMP (a nerve gas simulant) and 2-CEES (a blister agent simulant) were used as probes. Chemical an...

  18. Nanowire-based surface-enhanced Raman spectroscopy (SERS) for chemical warfare simulants (United States)

    Hoffmann, J. A.; Miragliotta, J. A.; Wang, J.; Tyagi, P.; Maddanimath, T.; Gracias, D. H.; Papadakis, S. J.


    Hand-held instruments capable of spectroscopic identification of chemical warfare agents (CWA) would find extensive use in the field. Because CWA can be toxic at very low concentrations compared to typical background levels of commonly-used compounds (flame retardants, pesticides) that are chemically similar, spectroscopic measurements have the potential to reduce false alarms by distinguishing between dangerous and benign compounds. Unfortunately, most true spectroscopic instruments (infrared spectrometers, mass spectrometers, and gas chromatograph-mass spectrometers) are bench-top instruments. Surface-acoustic wave (SAW) sensors are commercially available in hand-held form, but rely on a handful of functionalized surfaces to achieve specificity. Here, we consider the potential for a hand-held device based on surface enhanced Raman scattering (SERS) using templated nanowires as enhancing substrates. We examine the magnitude of enhancement generated by the nanowires and the specificity achieved in measurements of a range of CWA simulants. We predict the ultimate sensitivity of a device based on a nanowire-based SERS core to be 1-2 orders of magnitude greater than a comparable SAW system, with a detection limit of approximately 0.01 mg m-3.

  19. Efficacy of liquid and foam decontamination technologies for chemical warfare agents on indoor surfaces. (United States)

    Love, Adam H; Bailey, Christopher G; Hanna, M Leslie; Hok, Saphon; Vu, Alex K; Reutter, Dennis J; Raber, Ellen


    Bench-scale testing was used to evaluate the efficacy of four decontamination formulations on typical indoor surfaces following exposure to the liquid chemical warfare agents sarin (GB), soman (GD), sulfur mustard (HD), and VX. Residual surface contamination on coupons was periodically measured for up to 24h after applying one of four selected decontamination technologies [0.5% bleach solution with trisodium phosphate, Allen Vanguard Surface Decontamination Foam (SDF™), U.S. military Decon Green™, and Modec Inc. and EnviroFoam Technologies Sandia Decontamination Foam (DF-200)]. All decontamination technologies tested, except for the bleach solution, performed well on nonporous and nonpermeable glass and stainless-steel surfaces. However, chemical agent residual contamination typically remained on porous and permeable surfaces, especially for the more persistent agents, HD and VX. Solvent-based Decon Green™ performed better than aqueous-based bleach or foams on polymeric surfaces, possibly because the solvent is able to penetrate the polymer matrix. Bleach and foams out-performed Decon Green for penetrating the highly polar concrete surface. Results suggest that the different characteristics needed for an ideal and universal decontamination technology may be incompatible in a single formulation and a strategy for decontaminating a complex facility will require a range of technologies.

  20. Plastic antibody for the recognition of chemical warfare agent sulphur mustard. (United States)

    Boopathi, M; Suryanarayana, M V S; Nigam, Anil Kumar; Pandey, Pratibha; Ganesan, K; Singh, Beer; Sekhar, K


    Molecularly imprinted polymers (MIPs) known as plastic antibodies (PAs) represent a new class of materials possessing high selectivity and affinity for the target molecule. Since their discovery, PAs have attracted considerable interest from bio- and chemical laboratories to pharmaceutical institutes. PAs are becoming an important class of synthetic materials mimicking molecular recognition by natural receptors. In addition, they have been utilized as catalysts, sorbents for solid-phase extraction, stationary phase for liquid chromatography and mimics of enzymes. In this paper, first time we report the preparation and characterization of a PA for the recognition of blistering chemical warfare agent sulphur mustard (SM). The SM imprinted PA exhibited more surface area when compared to the control non-imprinted polymer (NIP). In addition, SEM image showed an ordered nano-pattern for the PA of SM that is entirely different from the image of NIP. The imprinting also enhanced SM rebinding ability to the PA when compared to the NIP with an imprinting efficiency (alpha) of 1.3.

  1. Modified clay minerals efficiency against chemical and biological warfare agents for civil human protection. (United States)

    Plachá, Daniela; Rosenbergová, Kateřina; Slabotínský, Jiří; Kutláková, Kateřina Mamulová; Studentová, Soňa; Martynková, Gražyna Simha


    Sorption efficiencies of modified montmorillonite and vermiculite of their mono ionic Na and organic HDTMA and HDP forms were studied against chemical and biological warfare agents such as yperite and selected bacterial strains. Yperite interactions with modified clay minerals were observed through its capture in low-density polyethylene foil-modified clay composites by measuring yperite gas permeation with using chemical indication and gas chromatography methods. The antibacterial activities of synthetized organoclays were tested against selected Gram-positive and Gram-negative bacterial species in minimum inhibitory concentration tests. The obtained results showed a positive influence of modified clay minerals on the significant yperite breakthrough-time increase. The most effective material was the polyethylene-Na form montmorillonite, while the polyethylene-Na form vermiculite showed the lowest efficiency. With increasing organic cations loading in the interlayer space the montmorillonite efficiency decreased, and in the case of vermiculite an opposite effect was observed. Generally the modified montmorillonites were more effective than modified vermiculites. The HDP cations seem to be more effective compare to the HDTMA. The antibacterial activity tests confirmed efficiency of all organically modified clay minerals against Gram-positive bacteria. The confirmation of antibacterial activity against Y. pestis, plague bacteria, is the most interesting result of this part of the study.

  2. Multifunctional ultra-high vacuum apparatus for studies of the interactions of chemical warfare agents on complex surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Wilmsmeyer, Amanda R.; Morris, John R. [Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24061 (United States); Gordon, Wesley O.; Mantooth, Brent A.; Lalain, Teri A. [Research and Technology Directorate, U.S. Army Edgewood Chemical Biological Center, Aberdeen Proving Ground, Maryland 21010 (United States); Davis, Erin Durke [OptiMetrics, Inc., Abingdon, Maryland 21009 (United States)


    A fundamental understanding of the surface chemistry of chemical warfare agents is needed to fully predict the interaction of these toxic molecules with militarily relevant materials, catalysts, and environmental surfaces. For example, rules for predicting the surface chemistry of agents can be applied to the creation of next generation decontaminants, reactive coatings, and protective materials for the warfighter. Here, we describe a multifunctional ultra-high vacuum instrument for conducting comprehensive studies of the adsorption, desorption, and surface chemistry of chemical warfare agents on model and militarily relevant surfaces. The system applies reflection-absorption infrared spectroscopy, x-ray photoelectron spectroscopy, and mass spectrometry to study adsorption and surface reactions of chemical warfare agents. Several novel components have been developed to address the unique safety and sample exposure challenges that accompany the research of these toxic, often very low vapor pressure, compounds. While results of vacuum-based surface science techniques may not necessarily translate directly to environmental processes, learning about the fundamental chemistry will begin to inform scientists about the critical aspects that impact real-world applications.

  3. The possible role of intravenous lipid emulsion in the treatment of chemical warfare agent poisoning

    Directory of Open Access Journals (Sweden)

    Arik Eisenkraft


    Full Text Available Organophosphates (OPs are cholinesterase inhibitors that lead to a characteristic toxidrome of hypersecretion, miosis, dyspnea, respiratory insufficiency, convulsions and, without proper and early antidotal treatment, death. Most of these compounds are highly lipophilic. Sulfur mustard is a toxic lipophilic alkylating agent, exerting its damage through alkylation of cellular macromolecules (e.g., DNA, proteins and intense activation of pro-inflammatory pathways. Currently approved antidotes against OPs include the peripheral anticholinergic drug atropine and an oxime that reactivates the inhibited cholinesterase. Benzodiazepines are used to stop organophosphate-induced seizures. Despite these approved drugs, efforts have been made to introduce other medical countermeasures in order to attenuate both the short-term and long-term clinical effects following exposure. Currently, there is no antidote against sulfur mustard poisoning. Intravenous lipid emulsions are used as a source of calories in parenteral nutrition. In recent years, efficacy of lipid emulsions has been shown in the treatment of poisoning by fat-soluble compounds in animal models as well as clinically in humans. In this review we discuss the usefulness of intravenous lipid emulsions as an adjunct to the in-hospital treatment of chemical warfare agent poisoning.

  4. Ultra-Fast Degradation of Chemical Warfare Agents Using MOF-Nanofiber Kebabs. (United States)

    Zhao, Junjie; Lee, Dennis T; Yaga, Robert W; Hall, Morgan G; Barton, Heather F; Woodward, Ian R; Oldham, Christopher J; Walls, Howard J; Peterson, Gregory W; Parsons, Gregory N


    The threat associated with chemical warfare agents (CWAs) motivates the development of new materials to provide enhanced protection with a reduced burden. Metal-organic frame-works (MOFs) have recently been shown as highly effective catalysts for detoxifying CWAs, but challenges still remain for integrating MOFs into functional filter media and/or protective garments. Herein, we report a series of MOF-nanofiber kebab structures for fast degradation of CWAs. We found TiO2 coatings deposited via atomic layer deposition (ALD) onto polyamide-6 nanofibers enable the formation of conformal Zr-based MOF thin films including UiO-66, UiO-66-NH2 , and UiO-67. Cross-sectional TEM images show that these MOF crystals nucleate and grow directly on and around the nanofibers, with strong attachment to the substrates. These MOF-functionalized nanofibers exhibit excellent reactivity for detoxifying CWAs. The half-lives of a CWA simulant compound and nerve agent soman (GD) are as short as 7.3 min and 2.3 min, respectively. These results therefore provide the earliest report of MOF-nanofiber textile composites capable of ultra-fast degradation of CWAs.

  5. Measurements of Raman scattering in the middle ultraviolet band from persistent chemical warfare agents (United States)

    Kullander, Fredrik; Landström, Lars; Lundén, Hampus; Mohammed, Abdesalam; Olofsson, Göran; Wästerby, Pär.


    The very low Raman scattering cross section and the fluorescence background limit the measuring range of Raman based instruments operating in the visible or infrared band. We are exploring if laser excitation in the middle ultraviolet (UV) band between 200 and 300 nm is useful and advantageous for detection of persistent chemical warfare agents (CWA) on various kinds of surfaces. The UV Raman scattering from tabun, mustard gas, VX and relevant simulants in the form of liquid surface contaminations has been measured using a laboratory experimental setup with a short standoff distance around 1 meter. Droplets having a volume of 1 μl were irradiated with a tunable pulsed laser swept within the middle UV band. A general trend is that the signal strength moves through an optimum when the laser excitation wavelength is swept between 240 and 300 nm. The signal from tabun reaches a maximum around 265 nm, the signal from mustard gas around 275 nm. The Raman signal from VX is comparably weak. Raman imaging by the use of a narrow bandpass UV filter is also demonstrated.

  6. Metabolic Syndrome in Chemical Warfare Patients with Chronic Obstructive Pulmonary Disease

    Directory of Open Access Journals (Sweden)

    Shahrzad M. Lari


    Full Text Available   Introduction: Sulfur mustard (SM, a toxic alkylating gas, can cause serious long-term pulmonary complications such as chronic obstructive pulmonary disease (COPD. Metabolic syndrome (MetS is one of the important comorbidities of COPD. This study was designed to evaluate the frequency of metabolic syndrome in Iranian chemical warfare patients (CWPs with COPD. Materials and Methods: Thirty CWPs with a mean age of 46.93± 6.8 were enrolled in this study. The following parameters were studied in: complete pulmonary function tests, health-related quality of life, serum triglycerides (TG, high density lipoprotein (HDL and fasting blood sugar (FBS levels. Additionally, 32 COPD patients and 56 healthy persons were considered as control groups who were matched to CWPs. Results: We found a statistically significant difference in the frequency of MetS between the COPD patients and the healthy control group (p=0.04. Additionally, we observed a statistically significant difference in the mean HDL levels among these groups (p=

  7. Toxicogenomic studies of human neural cells following exposure to organophosphorus chemical warfare nerve agent VX. (United States)

    Gao, Xiugong; Lin, Hsiuling; Ray, Radharaman; Ray, Prabhati


    Organophosphorus (OP) compounds represent an important group of chemical warfare nerve agents that remains a significant and constant military and civilian threat. OP compounds are considered acting primarily via cholinergic pathways by binding irreversibly to acetylcholinesterase, an important regulator of the neurotransmitter acetylcholine. Many studies over the past years have suggested that other mechanisms of OP toxicity exist, which need to be unraveled by a comprehensive and systematic approach such as genome-wide gene expression analysis. Here we performed a microarray study in which cultured human neural cells were exposed to 0.1 or 10 μM of VX for 1 h. Global gene expression changes were analyzed 6, 24, and 72 h post exposure. Functional annotation and pathway analysis of the differentially expressed genes has revealed many genes, networks and canonical pathways that are related to nervous system development and function, or to neurodegenerative diseases such as Alzheimer's disease, Huntington's disease, and Parkinson's disease. In particular, the neuregulin pathway impacted by VX exposure has important implications in many nervous system diseases including schizophrenia. These results provide useful information valuable in developing suitable antidotes for more effective prevention and treatment of, as well as in developing biomarkers for, VX-induced chronic neurotoxicity.

  8. Effects of CW (chemical warfare)-related chemicals on social behavior and performance. Annual report, 30 September 1984-29 September 1985

    Energy Technology Data Exchange (ETDEWEB)

    Bunnell, B.N.; Iturrian, W.B.


    This report summarizes work accomplished in the second year of a three-year project aimed at developing a battery of tests of social behavior and performance that wil be sensitive to the effects of chemical warfare-related chemicals considered for use as antidotes or prophylactics against chemical-warfare agents. Procedures for assessing social behavior in nonhuman primates are described and compared. Performance scores on three operant schedules, a test of complex problem solving, and behavior in a novel environment are presented and correlations between the social and performance variables are examined. The effects of atropines on several of the social and performance measures are reported as are data from plasma hormone assays for cortisol and prolactin.

  9. Evaluation of Chemical Warfare Agent Percutaneous Vapor Toxicity: Derivation of Toxicity Guidelines for Assessing Chemical Protective Ensembles.

    Energy Technology Data Exchange (ETDEWEB)

    Watson, A.P.


    Percutaneous vapor toxicity guidelines are provided for assessment and selection of chemical protective ensembles (CPEs) to be used by civilian and military first responders operating in a chemical warfare agent vapor environment. The agents evaluated include the G-series and VX nerve agents, the vesicant sulfur mustard (agent HD) and, to a lesser extent, the vesicant Lewisite (agent L). The focus of this evaluation is percutaneous vapor permeation of CPEs and the resulting skin absorption, as inhalation and ocular exposures are assumed to be largely eliminated through use of SCBA and full-face protective masks. Selection of appropriately protective CPE designs and materials incorporates a variety of test parameters to ensure operability, practicality, and adequacy. One aspect of adequacy assessment should be based on systems tests, which focus on effective protection of the most vulnerable body regions (e.g., the groin area), as identified in this analysis. The toxicity range of agent-specific cumulative exposures (Cts) derived in this analysis can be used as decision guidelines for CPE acceptance, in conjunction with weighting consideration towards more susceptible body regions. This toxicity range is bounded by the percutaneous vapor estimated minimal effect (EME{sub pv}) Ct (as the lower end) and the 1% population threshold effect (ECt{sub 01}) estimate. Assumptions of exposure duration used in CPE certification should consider that each agent-specific percutaneous vapor cumulative exposure Ct for a given endpoint is a constant for exposure durations between 30 min and 2 hours.

  10. Advances in toxicology and medical treatment of chemical warfare nerve agents

    Directory of Open Access Journals (Sweden)

    Moshiri Mohammd


    Full Text Available Abstract Organophosphorous (OP Nerve agents (NAs are known as the deadliest chemical warfare agents. They are divided into two classes of G and V agents. Most of them are liquid at room temperature. NAs chemical structures and mechanisms of actions are similar to OP pesticides, but their toxicities are higher than these compounds. The main mechanism of action is irreversible inhibition of Acetyl Choline Esterase (AChE resulting in accumulation of toxic levels of acetylcholine (ACh at the synaptic junctions and thus induces muscarinic and nicotinic receptors stimulation. However, other mechanisms have recently been described. Central nervous system (CNS depression particularly on respiratory and vasomotor centers may induce respiratory failure and cardiac arrest. Intermediate syndrome after NAs exposure is less common than OP pesticides poisoning. There are four approaches to detect exposure to NAs in biological samples: (I AChE activity measurement, (II Determination of hydrolysis products in plasma and urine, (III Fluoride reactivation of phosphylated binding sites and (IV Mass spectrometric determination of cholinesterase adducts. The clinical manifestations are similar to OP pesticides poisoning, but with more severity and fatalities. The management should be started as soon as possible. The victims should immediately be removed from the field and treatment is commenced with auto-injector antidotes (atropine and oximes such as MARK I kit. A 0.5% hypochlorite solution as well as novel products like M291 Resin kit, G117H and Phosphotriesterase isolated from soil bacterias, are now available for decontamination of NAs. Atropine and oximes are the well known antidotes that should be infused as clinically indicated. However, some new adjuvant and additional treatment such as magnesium sulfate, sodium bicarbonate, gacyclidine, benactyzine, tezampanel, hemoperfusion, antioxidants and bioscavengers have recently been used for OP NAs poisoning.

  11. Limitations and challenges in treatment of acute chemical warfare agent poisoning. (United States)

    Thiermann, Horst; Worek, Franz; Kehe, Kai


    Recent news from Syria on a possible use of chemical warfare agents made the headlines. Furthermore, the motivation of terrorists to cause maximal harm shifts these agents into the public focus. For incidents with mass casualties appropriate medical countermeasures must be available. At present, the most important threats arise from nerve agents and sulfur mustard. At first, self-protection and protection of medical units from contamination is of utmost importance. Volatile nerve agent exposure, e.g. sarin, results in fast development of cholinergic crisis. Immediate clinical diagnosis can be confirmed on-site by assessment of acetylcholinesterase activity. Treatment with autoinjectors that are filled with 2mg atropine and an oxime (at present obidoxime, pralidoxime, TMB-4 or HI-6) are not effective against all nerve agents. A more aggressive atropinisation has to be considered and more effective oximes (if possible with a broad spectrum or a combination of different oximes) as well as alternative strategies to cope with high acetylcholine levels at synaptic sites should be developed. A further gap exists for the treatment of patients with sustained cholinergic crisis that has to be expected after exposure to persistent nerve agents, e.g. VX. The requirement for long-lasting artificial ventilation can be reduced with an oxime therapy that is optimized by using the cholinesterase status for guidance or by measures (e.g. scavengers) that are able to reduce the poison load substantially in the patients. For sulfur mustard poisoning no specific antidote is available until now. Symptomatic measures as used for treatment of burns are recommended together with surgical or laser debridement. Thus, huge amounts of resources are expected to be consumed as wound healing is impaired. Possible depots of sulfur mustard in tissues may aggravate the situation. More basic knowledge is necessary to improve substantially therapeutic options. The use of stem cells may provide a new

  12. Research on the Interaction of Hydrogen-Bond Acidic Polymer Sensitive Sensor Materials with Chemical Warfare Agents Simulants by Inverse Gas Chromatography

    Directory of Open Access Journals (Sweden)

    Liu Yang


    Full Text Available Hydrogen-bond acidic polymers are important high affinity materials sensitive to organophosphates in the chemical warfare agent sensor detection process. Interactions between the sensor sensitive materials and chemical warfare agent simulants were studied by inverse gas chromatography. Hydrogen bonded acidic polymers, i.e., BSP3, were prepared for micro-packed columns to examine the interaction. DMMP (a nerve gas simulant and 2-CEES (a blister agent simulant were used as probes. Chemical and physical parameters such as heats of absorption and Henry constants of the polymers to DMMP and 2-CEES were determined by inverse gas chromatography. Details concerning absorption performance are also discussed in this paper.

  13. Research on the interaction of hydrogen-bond acidic polymer sensitive sensor materials with chemical warfare agents simulants by inverse gas chromatography. (United States)

    Yang, Liu; Han, Qiang; Cao, Shuya; Huang, Feng; Qin, Molin; Guo, Chenghai; Ding, Mingyu


    Hydrogen-bond acidic polymers are important high affinity materials sensitive to organophosphates in the chemical warfare agent sensor detection process. Interactions between the sensor sensitive materials and chemical warfare agent simulants were studied by inverse gas chromatography. Hydrogen bonded acidic polymers, i.e., BSP3, were prepared for micro-packed columns to examine the interaction. DMMP (a nerve gas simulant) and 2-CEES (a blister agent simulant) were used as probes. Chemical and physical parameters such as heats of absorption and Henry constants of the polymers to DMMP and 2-CEES were determined by inverse gas chromatography. Details concerning absorption performance are also discussed in this paper.

  14. Chemical and biological warfare: Biochemistry, therapy, and treatment. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning biochemistry, therapy, and treatment of the effects of military chemical and biological warfare agents. References include surveys and studies of immunizing agents and drugs, the efficacy of these drugs, and the effect of the drugs on the patient. Also included are biochemical studies, assay techniques, and antidote development, some of which is supported by animal studies. Citations concerning detection and warning, defoliants, protection, biology and toxicology, and general studies are covered in separate bibliographies.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  15. Chemical and biological warfare: Biochemistry, therapy, and treatment. (Latest citations from the NTIS bibliographic database). Published Search

    Energy Technology Data Exchange (ETDEWEB)



    The bibliography contains citations concerning biochemistry, therapy, and treatment of the effects of military chemical and biological warfare agents. References include surveys and studies of immunizing agents and drugs, the efficacy of these drugs, and the effect of the drugs on the patient. Also included are biochemical studies, assay techniques, and antidote development, some of which is supported by animal studies. Citations concerning detection and warning, defoliants, protection, biology and toxicology, and general studies are covered in separate bibliographies.(Contains 50-250 citations and includes a subject term index and title list.) (Copyright NERAC, Inc. 1995)

  16. Interleukin-6 and airflow limitation in chemical warfare patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Davood Attaran


    disease, interleukin-6, inflammation, chemical warfare

  17. Analysis of Urinary Metabolites of Nerve and Blister Chemical Warfare Agents (United States)


    Warfare Agents GA Tabun , ethyl dimethylphosphoramidate GB Sarin, isopropyl methylphosphonofluoridate GD Soman, pinacolyl methylphosphonofluoridate...and their metabolites Agent Metabolite GA, Tabun O P O N CN Ethyl Dimethylphosphoroamidate, EDMAP, GA Acid HO P O N CN GB, Sarin P O

  18. Chemical analysis of bleach and hydroxide-based solutions after decontamination of the chemical warfare agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX). (United States)

    Hopkins, F B; Gravett, M R; Self, A J; Wang, M; Chua, Hoe-Chee; Hoe-Chee, C; Lee, H S Nancy; Sim, N Lee Hoi; Jones, J T A; Timperley, C M; Riches, J R


    Detailed chemical analysis of solutions used to decontaminate chemical warfare agents can be used to support verification and forensic attribution. Decontamination solutions are amongst the most difficult matrices for chemical analysis because of their corrosive and potentially emulsion-based nature. Consequently, there are relatively few publications that report their detailed chemical analysis. This paper describes the application of modern analytical techniques to the analysis of decontamination solutions following decontamination of the chemical warfare agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX). We confirm the formation of N,N-diisopropylformamide and N,N-diisopropylamine following decontamination of VX with hypochlorite-based solution, whereas they were not detected in extracts of hydroxide-based decontamination solutions by nuclear magnetic resonance (NMR) spectroscopy or gas chromatography-mass spectrometry. We report the electron ionisation and chemical ionisation mass spectroscopic details, retention indices, and NMR spectra of N,N-diisopropylformamide and N,N-diisopropylamine, as well as analytical methods suitable for their analysis and identification in solvent extracts and decontamination residues.

  19. How Do I Know? A Guide to the Selection of Personal Protective Equipment for Use in Responding to A Release of Chemical Warfare Agents

    Energy Technology Data Exchange (ETDEWEB)

    Foust, C.B.


    An incident involving chemical warfare agents requires a unique hazardous materials (HAZMAT) response. As with an HAZMAT event, federal regulations prescribe that responders must be protected from exposure to the chemical agents. But unlike other HAZMAT events, special considerations govern selection of personal protective equipment (PPE). PPE includes all clothing, respirators and monitoring devices used to respond to a chemical release. PPE can differ depending on whether responders are military or civilian personnel.

  20. Determination of contamination of a chemical warfare-proof operating theatre with volatile anaesthetic agents and assessment of anaesthetic gas scavenging systems. (United States)

    Yoganathan, S; Johnston, I G; Parnell, C J; Houghton, I T; Restall, J


    Three types of anaesthetic waste scavenging systems (active antipollution system, Papworth Block passive system and activated charcoal absorber system) were compared with a non-scavenging control to assess their effectiveness in reducing waste halothane concentrations in a chemical warfare-proof operating theatre. All three systems were found to reduce the level of pollution significantly.

  1. Dual-Function Metal-Organic Framework as a Versatile Catalyst for Detoxifying Chemical Warfare Agent Simulants. (United States)

    Liu, Yangyang; Moon, Su-Young; Hupp, Joseph T; Farha, Omar K


    The nanocrystals of a porphyrin-based zirconium(IV) metal-organic framework (MOF) are used as a dual-function catalyst for the simultaneous detoxification of two chemical warfare agent simulants at room temperature. Simulants of nerve agent (such as GD, VX) and mustard gas, dimethyl 4-nitrophenyl phosphate and 2-chloroethyl ethyl sulfide, have been hydrolyzed and oxidized, respectively, to nontoxic products via a pair of pathways catalyzed by the same MOF. Phosphotriesterase-like activity of the Zr6-containing node combined with photoactivity of the porphyrin linker gives rise to a versatile MOF catalyst. In addition, bringing the MOF crystals down to the nanoregime leads to acceleration of the catalysis.

  2. Wearable Atmospheric Pressure Plasma Fabrics Produced by Knitting Flexible Wire Electrodes for the Decontamination of Chemical Warfare Agents (United States)

    Jung, Heesoo; Seo, Jin Ah; Choi, Seungki


    One of the key reasons for the limited use of atmospheric pressure plasma (APP) is its inability to treat non-flat, three-dimensional (3D) surface structures, such as electronic devices and the human body, because of the rigid electrode structure required. In this study, a new APP system design—wearable APP (WAPP)—that utilizes a knitting technique to assemble flexible co-axial wire electrodes into a large-area plasma fabric is presented. The WAPP device operates in ambient air with a fully enclosed power electrode and grounded outer electrode. The plasma fabric is flexible and lightweight, and it can be scaled up for larger areas, making it attractive for wearable APP applications. Here, we report the various plasma properties of the WAPP device and successful test results showing the decontamination of toxic chemical warfare agents, namely, mustard (HD), soman (GD), and nerve (VX) agents.

  3. Hand-held analyser based on microchip electrophoresis with contactless conductivity detection for measurement of chemical warfare agent degradation products (United States)

    Duran, Karolina-Petkovic; Zhu, Yonggang; Chen, Chuanpin; Swallow, Anthony; Stewart, Robert; Hoobin, Pam; Leech, Patrick; Ovenden, Simon


    This paper reports on the development of a hand-held device for on-site detection of organophosphonate nerve agent degradation products. This field-deployable analyzer relies on efficient microchip electrophoresis separation of alkyl methylphosphonic acids and their sensitive contactless conductivity detection. Miniaturized, low-powered design is coupled with promising analytical performance for separating the breakdown products of chemical warfare agents such as Soman, Sarin and VX . The detector has a detection limit of about 10 μg/mL and has a good linear response in the range 10-300 μg/mL concentration range. Applicability to environmental samples is demonstrated .The new hand-held analyzer offers great promise for converting conventional ion chromatography or capillary electrophoresis sophisticated systems into a portable forensic laboratory for faster, simpler and more reliable on-site screening.

  4. The Findings of HRCT of the Lung in Chemical Warfare Veterans with Previous Sulfur Mustard (SM Gas Exposure

    Directory of Open Access Journals (Sweden)

    Saeed Naghibi


    Full Text Available "nIntroduction: To identify the findings of High-Resolution Computed Tomography (HRCT of the lung in chemical warfare veterans with previous sulfur mustard (SM gas exposure. "nMaterials and Methods: 93 patients were studied prospectively 22 years after exposure. Demographic and clinical data were recorded. HRCT of the lung was performed during expiration and was reported double blinded by two radiologists. HRCT findings include air trapping, mosaic attenuation, ground glass attenuation, nodules, signet ring, fibrosis, bronchial wall thickening, bronchodilation, tree in bud, interlobular wall thickening, bulla, cavity, air consolidation, honey comb and mediastinal and pleural abnormalities that were analyzed. Final diagnosis was identified according to HRCT findings. The relation between HRCT findings, final diagnosis and the distribution of the abnormalities with duration after exposure were evaluated. Distribution of each finding was also evaluated. "nb The most frequent HRCT finding was air trapping (56.7%. Other common findings were mosaic attenuation (35.1%, ground glass attenuation (20.6%, nodules (17.5%, signet ring (15.5% and fibrosis(12.4%. Distribution of the abnormalities were mostly local (79.4% and bilateral (73%. Abnormalities were mostly in the lower lobe (61.3%. No significant correlation was found between the HRCT findings and the duration after exposure or distribution of the abnormalities. The respiratory complications diagnosed according to HRCT included bronchiolitis obliterans (43%, chronic obstructive pulmonary disease (COPD (27.9%, asthma (23.6%, bronchiectasis (13.9%, interstitial lung disease (ILD (9.6%. All abnormalities were seen more frequently in patients with lesser duration of exposure.( P-value < 0.05. "nConclusion: Focal bilateral air trapping was the most common finding seen in expiratory HRCT in this study, and it is highly suggestive of bronchiolitis obliterance (BO. BO can be a late complication of SM

  5. Surface with two paint strips for detection and warning of chemical warfare and radiological agents (United States)

    Farmer, Joseph C.


    A system for warning of corrosion, chemical, or radiological substances. The system comprises painting a surface with a paint or coating that includes an indicator material and monitoring the surface for indications of the corrosion, chemical, or radiological substances.

  6. In Situ Probes of Capture and Decomposition of Chemical Warfare Agent Simulants by Zr-Based Metal Organic Frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Plonka, Anna M.; Wang, Qi; Gordon, Wesley O.; Balboa, Alex; Troya, Diego; Guo, Weiwei; Sharp, Conor H.; Senanayake, Sanjaya D.; Morris, John R.; Hill, Craig L.; Frenkel, Anatoly I.


    Zr-based metal organic frameworks (MOFs) have been recently shown to be among the fastest catalysts of nerve-agent hydrolysis in solution. We report a detailed study of the adsorption and decomposition of a nerve-agent simulant, dimethyl methylphosphonate (DMMP), on UiO-66, UiO-67, MOF-808, and NU-1000 using synchrotron-based X-ray powder diffraction, X-ray absorption, and infrared spectroscopy, which reveals key aspects of the reaction mechanism. The diffraction measurements indicate that all four MOFs adsorb DMMP (introduced at atmospheric pressures through a flow of helium or air) within the pore space. In addition, the combination of X-ray absorption and infrared spectra suggests direct coordination of DMMP to the Zr6 cores of all MOFs, which ultimately leads to decomposition to phosphonate products. These experimental probes into the mechanism of adsorption and decomposition of chemical warfare agent simulants on Zr-based MOFs open new opportunities in rational design of new and superior decontamination materials.

  7. The application of single particle aerosol mass spectrometry for the detection and identification of high explosives and chemical warfare agents

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Audrey Noreen [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    Single Particle Aerosol Mass Spectrometry (SPAMS) was evaluated as a real-time detection technique for single particles of high explosives. Dual-polarity time-of-flight mass spectra were obtained for samples of 2,4,6-trinitrotoluene (TNT), 1,3,5-trinitro-1,3,5-triazinane (RDX), and pentaerythritol tetranitrate (PETN); peaks indicative of each compound were identified. Composite explosives, Comp B, Semtex 1A, and Semtex 1H were also analyzed, and peaks due to the explosive components of each sample were present in each spectrum. Mass spectral variability with laser fluence is discussed. The ability of the SPAMS system to identify explosive components in a single complex explosive particle (~1 pg) without the need for consumables is demonstrated. SPAMS was also applied to the detection of Chemical Warfare Agent (CWA) simulants in the liquid and vapor phases. Liquid simulants for sarin, cyclosarin, tabun, and VX were analyzed; peaks indicative of each simulant were identified. Vapor phase CWA simulants were adsorbed onto alumina, silica, Zeolite, activated carbon, and metal powders which were directly analyzed using SPAMS. The use of metal powders as adsorbent materials was especially useful in the analysis of triethyl phosphate (TEP), a VX stimulant, which was undetectable using SPAMS in the liquid phase. The capability of SPAMS to detect high explosives and CWA simulants using one set of operational conditions is established.

  8. Express analysis of explosives, chemical warfare agents and drugs with multicapillary column gas chromatography and ion mobility increment spectrometry. (United States)

    Buryakov, Igor A


    Description of a gas chromatograph designed for express analysis of explosives (2,4-dinitrotoluene, 2,4,6-trinitrotoluene, pentaerythritol tetranitrate), chemical warfare agents (mustard gas, lewisite, sarin) and drugs (heroin, cocaine hydrochloride, crack) is given. The devices comprises a multicapillary chromatographic column and an ion mobility increment spectrometer (MCC-IMIS). The main analytical characteristics of an IMIS (estimated detection limit (DL), linear dynamic range (LDR), speed of response) and a chromatographic column (separation power, degree of separation, a number of possible peaks at a chromatogram section, divided by analysis time) are determined. The maximum value of DL equal to 5 pg/ml was registered for cis-alpha-LW, and the lowest one of 0.001 pg/ml was for cocaine. The maximum value of LDR equal to 1000 was registered for sarin and the lowest one of 150 was for the ions of lewisite. Speed of response of one compound detection with the IMIS was 0.7 s.

  9. Efficient hydrolysis of the chemical warfare nerve agent tabun by recombinant and purified human and rabbit serum paraoxonase 1. (United States)

    Valiyaveettil, Manojkumar; Alamneh, Yonas; Biggemann, Lionel; Soojhawon, Iswarduth; Doctor, Bhupendra P; Nambiar, Madhusoodana P


    Paraoxonase 1 (PON1) has been described as an efficient catalytic bioscavenger due to its ability to hydrolyze organophosphates (OPs) and chemical warfare nerve agents (CWNAs). It is the future most promising candidate as prophylactic medical countermeasure against highly toxic OPs and CWNAs. Most of the studies conducted so far have been focused on the hydrolyzing potential of PON1 against nerve agents, sarin, soman, and VX. Here, we investigated the hydrolysis of tabun by PON1 with the objective of comparing the hydrolysis potential of human and rabbit serum purified and recombinant human PON1. The hydrolysis potential of PON1 against tabun, sarin, and soman was evaluated by using an acetylcholinesterase (AChE) back-titration Ellman method. Efficient hydrolysis of tabun (100 nM) was observed with ∼25-40 mU of PON1, while higher concentration (80-250 mU) of the enzyme was required for the complete hydrolysis of sarin (11 nM) and soman (3 nM). Our data indicate that tabun hydrolysis with PON1 was ∼30-60 times and ∼200-260 times more efficient than that with sarin and soman, respectively. Moreover, the catalytic activity of PON1 varies from source to source, which also reflects their efficiency of hydrolyzing different types of nerve agents. Thus, efficient hydrolysis of tabun by PON1 suggests its promising potential as a prophylactic treatment against tabun exposure.

  10. Using Metal Complex Ion-Molecule Reactions in a Miniature Rectilinear Ion Trap Mass Spectrometer to Detect Chemical Warfare Agents (United States)

    Graichen, Adam M.; Vachet, Richard W.


    The gas-phase reactions of a series of coordinatively unsaturated [Ni(L)n]y+ complexes, where L is a nitrogen-containing ligand, with chemical warfare agent (CWA) simulants in a miniature rectilinear ion trap mass spectrometer were investigated as part of a new approach to detect CWAs. Results show that upon entering the vacuum system via a poly(dimethylsiloxane) (PDMS) membrane introduction, low concentrations of several CWA simulants, including dipropyl sulfide (simulant for mustard gas), acetonitrile (simulant for the nerve agent tabun), and diethyl phosphite (simulant for nerve agents sarin, soman, tabun, and VX), can react with metal complex ions generated by electrospray ionization (ESI), thereby providing a sensitive means of detecting these compounds. The [Ni(L)n]2+ complexes are found to be particularly reactive with the simulants of mustard gas and tabun, allowing their detection at low parts-per-billion (ppb) levels. These detection limits are well below reported exposure limits for these CWAs, which indicates the applicability of this new approach, and are about two orders of magnitude lower than electron ionization detection limits on the same mass spectrometer. The use of coordinatively unsaturated metal complexes as reagent ions offers the possibility of further tuning the ion-molecule chemistry so that desired compounds can be detected selectively or at even lower concentrations.

  11. Decomposition of 2-chloroethylethylsulfide on copper oxides to detoxify polymer-based spherical activated carbons from chemical warfare agents. (United States)

    Fichtner, S; Hofmann, J; Möller, A; Schrage, C; Giebelhausen, J M; Böhringer, B; Gläser, R


    For the decomposition of chemical warfare agents, a hybrid material concept was applied. This consists of a copper oxide-containing phase as a component with reactive functionality supported on polymer-based spherical activated carbon (PBSAC) as a component with adsorptive functionality. A corresponding hybrid material was prepared by impregnation of PBSAC with copper(II)nitrate and subsequent calcination at 673K. The copper phase exists predominantly as copper(I)oxide which is homogeneously distributed over the PBSAC particles. The hybrid material containing 16 wt.% copper on PBSAC is capable of self-detoxifying the mustard gas surrogate 2-chloroethylethylsulfide (CEES) at room temperature. The decomposition is related to the breakthrough behavior of the reactant CEES, which displaces the reaction product ethylvinylsulfide (EVS). This leads to a combined breakthrough of CEES and EVS. The decomposition of CEES is shown to occur catalytically over the copper-containing PBSAC material. Thus, the hybrid material can even be considered to be self-cleaning.

  12. Continuum Model for Decontamination of Chemical Warfare Agent from a Rubbery Polymer using the Maxwell-Stefan Formulation (United States)

    Varady, Mark; Bringuier, Stefan; Pearl, Thomas; Stevenson, Shawn; Mantooth, Brent

    Decontamination of polymers exposed to chemical warfare agents (CWA) often proceeds by application of a liquid solution. Absorption of some decontaminant components proceed concurrently with extraction of the CWA, resulting in multicomponent diffusion in the polymer. In this work, the Maxwell-Stefan equations were used with the Flory-Huggins model of species activity to mathematically describe the transport of two species within a polymer. This model was used to predict the extraction of the nerve agent O-ethyl S-[2(diisopropylamino)ethyl] methylphosphonothioate (VX) from a silicone elastomer into both water and methanol. Comparisons with experimental results show good agreement with minimal fitting of model parameters from pure component uptake data. Reaction of the extracted VX with sodium hydroxide in the liquid-phase was also modeled and used to predict the overall rate of destruction of VX. Although the reaction proceeds more slowly in the methanol-based solution compared to the aqueous solution, the extraction rate is faster due to increasing VX mobility as methanol absorbs into the silicone, resulting in an overall faster rate of VX destruction.

  13. Chemical and Biological Warfare: Should Rapid Detection Techniques Be Researched To Dissuade Usage? A Review


    Mark R. Hurst; Ebtisam Wilkins


    Chemistry, microbiology and genetic engineering have opened new doorways for the human race to propel itself to a better future. However, there is a darker side to Bioengineering. One element of this is the manufacture and proliferation of biological and chemical weapons. It is clearly in the interest of humankind to prevent the future use of such weapons of mass destruction. Though many agents have been proposed as potential biological and chemical weapons, the feasibility of these weapons i...

  14. Governing Warfare

    DEFF Research Database (Denmark)

    Harste, Gorm

      It would seem as though warfare has gotten out of control, not only in Iraq and Afghanistan, but also in Central Africa. The paper outlines the strategic history of politically controlled warfare since the early Enlightenment. The argument is that control is implausible. The idea of control has...... the risks of lacking unity and displays the organisational trap to the fatal political myth of controlled warfare: Does it come from the military organisation system itself, from political ideologies of goal-rational governance, or from the chameleonic logic of wars?  ...... administration. While organisation systems continue to make some kind of political control possible, this is not the case in relation to wars. The organisation system is the in-between that should mediatise politics and war but is not functionally equivalent to just and unjust wars. The paper investigates...

  15. Roman Warfare

    Directory of Open Access Journals (Sweden)

    D.B. Saddington


    Full Text Available

    ROTH, Jonathan P 2009. Roman Warfare. Cambridge: Cambridge University Press. Pbk. R250. ISBN 978-0-521-53726-1.

    Jonathan Roth of San Jose State University, known as an expert on military logistics, has written this attractive Cambridge Introduction to Roman Civilization volume on Roman Warfare. The series is designed for students with no prior knowledge of Roman antiquity. The book comprises an Introduction on Sources and Methods (pp. 1-6 and 15 chapters on Roman warfare from the beginnings to the fall of the Western Empire in AD 476, using a chronological approach. There are 68 illustrations and maps, a Timeline, a Glossary, a Glossary of People, a Bibliography (which includes several websites and an Index.

  16. Handheld and mobile hyperspectral imaging sensors for wide-area standoff detection of explosives and chemical warfare agents (United States)

    Gomer, Nathaniel R.; Gardner, Charles W.; Nelson, Matthew P.


    Hyperspectral imaging (HSI) is a valuable tool for the investigation and analysis of targets in complex background with a high degree of autonomy. HSI is beneficial for the detection of threat materials on environmental surfaces, where the concentration of the target of interest is often very low and is typically found within complex scenery. Two HSI techniques that have proven to be valuable are Raman and shortwave infrared (SWIR) HSI. Unfortunately, current generation HSI systems have numerous size, weight, and power (SWaP) limitations that make their potential integration onto a handheld or field portable platform difficult. The systems that are field-portable do so by sacrificing system performance, typically by providing an inefficient area search rate, requiring close proximity to the target for screening, and/or eliminating the potential to conduct real-time measurements. To address these shortcomings, ChemImage Sensor Systems (CISS) is developing a variety of wide-field hyperspectral imaging systems. Raman HSI sensors are being developed to overcome two obstacles present in standard Raman detection systems: slow area search rate (due to small laser spot sizes) and lack of eye-safety. SWIR HSI sensors have been integrated into mobile, robot based platforms and handheld variants for the detection of explosives and chemical warfare agents (CWAs). In addition, the fusion of these two technologies into a single system has shown the feasibility of using both techniques concurrently to provide higher probability of detection and lower false alarm rates. This paper will provide background on Raman and SWIR HSI, discuss the applications for these techniques, and provide an overview of novel CISS HSI sensors focused on sensor design and detection results.

  17. Facile hydrolysis-based chemical destruction of the warfare agents VX, GB, and HD by alumina-supported fluoride reagents. (United States)

    Gershonov, E; Columbus, I; Zafrani, Y


    A facile solvent-free hydrolysis (chemical destruction) of the warfare agents VX (O-ethyl S-2-(diisopropylamino)ethyl methylphosphonothioate), GB (O-isopropyl methylphosphonofluoridate or sarin), and HD (2,2'-dichloroethyl sulfide or sulfur mustard) upon reaction with various solid-supported fluoride reagents is described. These solid reagents include different alumina-based powders such as KF/Al(2)O(3), AgF/KF/Al(2)O(3), and KF/Al(2)O(3) enriched by so-called coordinatively unsaturated fluoride ions (termed by us as ECUF-KF/Al(2)O(3)). When adsorbed on these sorbents, the nerve agent VX quickly hydrolyzed (t(1/2) range between 0.1-6.3 h) to the corresponding nontoxic phosphonic acid EMPA as a major product (>90%) and to the relatively toxic desethyl-VX (<10%). The latter byproduct was further hydrolyzed to the nontoxic MPA product (t(1/2) range between 2.2-161 h). The reaction rates and the product distribution were found to be strongly dependent on the nature of the fluoride ions in the KF/Al(2)O(3) matrix and on its water content. All variations of the alumina-supported fluoride reagents studied caused an immediate hydrolysis of the highly toxic GB (t(1/2) < 10 min) to form the corresponding nontoxic phosphonic acid IMPA. A preliminary study of the detoxification of HD on these catalyst supports showed the formation of the nontoxic 1,4-thioxane as a major product together with minor amounts of TDG and vinylic compounds within a few days. The mechanisms and the efficiency of these processes were successfully studied by solid-state (31)P, (13)C, and (19)F MAS NMR.

  18. Photoassisted reaction of chemical warfare agent VX droplets under UV light irradiation. (United States)

    Zuo, Guo-Min; Cheng, Zhen-Xing; Li, Guo-Wen; Wang, Lian-Yuan; Chen, Hong


    A photoassisted reaction of O-ethyl S-[2-(diisopropylamino) ethyl] methylphosphonothioate (VX) droplets in air was carried out. The experimental results indicated that VX droplets could be easily and chemically transformed into other compounds under irradiation of a germicidal lamp over sufficient time. Quantum chemical calculation results demonstrated that UV light less than 278 nm wavelength could possibly initiate photoreaction of VX and that both P-S and P=O bonds in the VX molecule were lengthened. The identification of reaction products by gas and liquid chromatography mass spectroscopy and NMR revealed that the VX molecule in air under UV light irradiation could undergo isomerization of S-esters to O-esters, cleavage of P-S, S-C, and C-N bonds, and ozonation of tertiary amines.

  19. A Review of the Disruptive Potential of Botulinum Neurotoxins as Chemical Warfare Agents (United States)


    dangerous chemical weapon (persistence in vivo, exceedingly high potency, ease of distribution and ease of production) also make it highly...caused by ingestion of botulinum neurotoxin (BoNT) was first described as “ sausage poisoning” in 1820 and attributed to a bacterium in 1897 [1]. We...intoxication of susceptible hosts invariably results in neuromuscular paralysis. The same characteristics that make the BoNTs the most lethal substances

  20. Toxicity of the Organophosphate Chemical Warfare Agents GA, GB, and VX: Implications for Public Protection.


    Munro, N


    The nerve agents, GA, GB, and VX are organophosphorus esters that form a major portion of the total agent volume contained in the U.S. stockpile of unitary chemical munitions. Congress has mandated the destruction of these agents, which is currently slated for completion in 2004. The acute, chronic, and delayed toxicity of these agents is reviewed in this analysis. The largely negative results from studies of genotoxicity, carcinogenicity, developmental, and reproductive toxicity are also pre...

  1. Procedures, Requirements and Challenges Associated with Analysis of Environmental Samples for Chemical Warfare Material (CWM) (United States)


    TN • Edwards AFB , CA • Ogden, UT • Ft. McClellan , AL • Camp Sibert, AL • Brooksville AAF, FL • Cleveland Plant, OH • Holloman AFB , NM • Lowry BGR...0.064) 19 (0.018) 100 (0.053) Approved for Public Release CONUS Projects • England AFB , LA • Redstone Arsenal, AL • Spring Valley DC • Memphis Depot...Deseret Chemical Depot, UT • Rocky Mt Arsenal, CO • Dover AFB , DE • Bluegrass, KY• Newport, IN • Dugway, UT Approved for Public Release OCONUS Projects

  2. Environmental toxicity of Chemical Warfare Agents (CWAs) - MicrotoxTM and Spontaneous Locomotor Changes

    DEFF Research Database (Denmark)

    Storgaard, Morten Swayne; Sanderson, Hans; Baatrup, Erik

    After the 2nd World War the CWAs were prohibited by law and 11,000 tonnes of toxic agents were dumped in the Bornholm Basin east of Bornholm. The dumped chemical munitions have not reached attention from politicians and scientists until recently. During earlier projects, such as MERCW (2005...... to be illuminated in which this study hopefully will contribute to. Especially, chronic toxicity needs to be described as this mimics a more environmentally realistic situation. One or two compounds will be accessed based upon various factors such as detection frequencies, found concentrations in both sediment...... to the commercially important cod (Gadus morrhua). The cod migrates down to the seafloor – even crossing the oxycline - where the CWA munitions were dumped. To sum up, this study will obtain novel ecotoxicity data on recently discovered degradation products and assess the potential threat to the commercially...

  3. Decontamination of Chemical/Biological Warfare (CBW) Agents Using an Atmospheric Pressure Plasma Jet (APPJ) (United States)

    Herrmann, Hans W.


    The atmospheric pressure plasma jet (APPJ) is a non-thermal, high pressure, uniform glow discharge that produces a high velocity effluent stream of highly reactive chemical species. The discharge operates on a feedstock gas (e.g. He/O_2/H_2O) which flows between an outer, grounded, cylindrical electrode and an inner, coaxial electrode powered at 13.56 MHz RF. While passing through the plasma, the feedgas becomes excited, dissociated or ionized by electron impact. Once the gas exits the discharge volume, ions and electrons are rapidly lost by recombination, but the fast-flowing effluent still contains metastables (e.g. O2*, He*) and radicals (e.g. O, OH). These reactive species have been shown to be effective neutralizers of surrogates for anthrax spores, mustard blister agent and VX nerve gas. Unlike conventional, wet decontamination methods, the plasma effluent does not cause corrosion of most surfaces and does not damage wiring, electronics, nor most plastics. This makes it highly suitable for decontamination of high value sensitive equipment such as is found in vehicle interiors (i.e. tanks, planes...) for which there is currently no good decontamination technique. Furthermore, the reactive species rapidly degrade into harmless products leaving no lingering residue or harmful byproducts. Physics of the APPJ will be discussed and results of surface decontamination experiments using simulant and actual CBW agents will be presented.

  4. Sensitive monitoring of volatile chemical warfare agents in air by atmospheric pressure chemical ionization mass spectrometry with counter-flow introduction. (United States)

    Seto, Yasuo; Kanamori-Kataoka, Mieko; Tsuge, Koichiro; Ohsawa, Isaac; Iura, Kazumitsu; Itoi, Teruo; Sekiguchi, Hiroyuki; Matsushita, Koji; Yamashiro, Shigeharu; Sano, Yasuhiro; Sekiguchi, Hiroshi; Maruko, Hisashi; Takayama, Yasuo; Sekioka, Ryoji; Okumura, Akihiko; Takada, Yasuaki; Nagano, Hisashi; Waki, Izumi; Ezawa, Naoya; Tanimoto, Hiroyuki; Honjo, Shigeru; Fukano, Masumi; Okada, Hidehiro


    A new method for sensitively and selectively detecting chemical warfare agents (CWAs) in air was developed using counter-flow introduction atmospheric pressure chemical ionization mass spectrometry (MS). Four volatile and highly toxic CWAs were examined, including the nerve gases sarin and tabun, and the blister agents mustard gas (HD) and Lewisite 1 (L1). Soft ionization was performed using corona discharge to form reactant ions, and the ions were sent in the direction opposite to the airflow by an electric field to eliminate the interfering neutral molecules such as ozone and nitrogen oxide. This resulted in efficient ionization of the target CWAs, especially in the negative ionization mode. Quadrupole MS (QMS) and ion trap tandem MS (ITMS) instruments were developed and investigated, which were movable on the building floor. For sarin, tabun, and HD, the protonated molecular ions and their fragment ions were observed in the positive ion mode. For L1, the chloride adduct ions of L1 hydrolysis products were observed in negative ion mode. The limit of detection (LOD) values in real-time or for a 1 s measurement monitoring the characteristic ions were between 1 and 8 μg/m(3) in QMS instrument. Collision-induced fragmentation patterns for the CWAs were observed in an ITMS instrument, and optimized combinations of the parent and daughter ion pairs were selected to achieve real-time detection with LOD values of around 1 μg/m(3). This is a first demonstration of sensitive and specific real-time detection of both positively and negatively ionizable CWAs by MS instruments used for field monitoring.

  5. Analysis of chemical warfare agents in organic liquid samples with magnetic dispersive solid phase extraction and gas chromatography mass spectrometry for verification of the chemical weapons convention. (United States)

    Singh, Varoon; Purohit, Ajay Kumar; Chinthakindi, Sridhar; Goud, Raghavender D; Tak, Vijay; Pardasani, Deepak; Shrivastava, Anchal Roy; Dubey, Devendra Kumar


    A simple, sensitive and low temperature sample preparation method is developed for detection and identification of Chemical Warfare Agents (CWAs) and scheduled esters in organic liquid using magnetic dispersive solid phase extraction (MDSPE) followed by gas chromatography-mass spectrometry analysis. The method utilizes Iron oxide@Poly(methacrylic acid-co-ethylene glycol dimethacrylate) resin (Fe2O3@Poly(MAA-co-EGDMA)) as sorbent. Variants of these sorbents were prepared by precipitation polymerization of methacrylic acid-co-ethylene glycol dimethacrylate (MAA-co-EGDMA) onto Fe2O3 nanoparticles. Fe2O3@poly(MAA-co-EGDMA) with 20% MAA showed highest recovery of analytes. Extractions were performed with magnetic microspheres by MDSPE. Parameters affecting the extraction efficiency were studied and optimized. Under the optimized conditions, method showed linearity in the range of 0.1-3.0μgmL(-1) (r(2)=0.9966-0.9987). The repeatability and reproducibility (relative standard deviations (RSDs) %) were in the range of 4.5-7.6% and 3.4-6.2% respectively for organophosphorous esters in dodecane. Limits of detection (S/N=3/1) and limit of quantification (S/N=10/1) were found to be in the range of 0.05-0.1μgmL(-1) and 0.1-0.12μgmL(-1) respectively in SIM mode for selected analytes. The method was successfully validated and applied to the extraction and identification of targeted analytes from three different organic liquids i.e. n-hexane, dodecane and silicon oil. Recoveries ranged from 58.7 to 97.3% and 53.8 to 95.5% at 3μgmL(-1) and 1μgmL(-1) spiking concentrations. Detection of diethyl methylphosphonate (DEMP) and O-Ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX) in samples provided by the Organization for Prohibition of Chemical Weapons Proficiency Test (OPCW-PT) proved the utility of the developed method for the off-site analysis of CWC relevant chemicals.

  6. Bioaccumulation of chemical warfare agents, energetic materials, and metals in deep-sea shrimp from discarded military munitions sites off Pearl Harbor (United States)

    Koide, Shelby; Silva, Jeff A. K.; Dupra, Vilma; Edwards, Margo


    The bioaccumulation of munitions-related chemicals at former military deep-water disposal sites is poorly understood. This paper presents the results of human-food-item biota sampling to assess the potential for bioaccumulation of chemical warfare agents, energetic materials, arsenic, and additional munitions-related metals in deep-sea shrimp tissue samples collected during the Hawai'i Undersea Military Munitions Assessment (HUMMA) project to date. The HUMMA investigation area is located within a former munitions sea-disposal site located south of Pearl Harbor on the island of O'ahu, Hawai'i, designated site Hawaii-05 (HI-05) by the United States Department of Defense. Indigenous deep-sea shrimp (Heterocarpus ensifer) were caught adjacent to discarded military munitions (DMM) and at control sites where munitions were absent. Tissue analysis results showed that chemical warfare agents and their degradation products were not present within the edible portions of these samples at detectable concentrations, and energetic materials and their degradation products were detected in only a few samples at concentrations below the laboratory reporting limits. Likewise, arsenic, copper, and lead concentrations were below the United States Food and Drug Administration's permitted concentrations of metals in marine biota tissue (if defined), and their presence within these samples could not be attributed to the presence of DMM within the study area based on a comparative analysis of munitions-adjacent and control samples collected. Based on this current dataset, it can be concluded that DMM existing within the HUMMA study area is not contributing to the bioaccumulation of munitions-related chemicals for the biota species investigated to date.

  7. Graphene oxide as sensitive layer in Love-wave surface acoustic wave sensors for the detection of chemical warfare agent simulants. (United States)

    Sayago, Isabel; Matatagui, Daniel; Fernández, María Jesús; Fontecha, José Luis; Jurewicz, Izabela; Garriga, Rosa; Muñoz, Edgar


    A Love-wave device with graphene oxide (GO) as sensitive layer has been developed for the detection of chemical warfare agent (CWA) simulants. Sensitive films were fabricated by airbrushing GO dispersions onto Love-wave devices. The resulting Love-wave sensors detected very low CWA simulant concentrations in synthetic air at room temperature (as low as 0.2 ppm for dimethyl-methylphosphonate, DMMP, a simulant of sarin nerve gas, and 0.75 ppm for dipropylene glycol monomethyl ether, DPGME, a simulant of nitrogen mustard). High responses to DMMP and DPGME were obtained with sensitivities of 3087 and 760 Hz/ppm respectively. Very low limit of detection (LOD) values (9 and 40 ppb for DMMP and DPGME, respectively) were calculated from the achieved experimental data. The sensor exhibited outstanding sensitivity, good linearity and repeatability to all simulants tested. The detection mechanism is here explained in terms of hydrogen bonding formation between the tested CWA simulants and GO.

  8. Ion mobility spectrometric analysis of vaporous chemical warfare agents by the instrument with corona discharge ionization ammonia dopant ambient temperature operation. (United States)

    Satoh, Takafumi; Kishi, Shintaro; Nagashima, Hisayuki; Tachikawa, Masumi; Kanamori-Kataoka, Mieko; Nakagawa, Takao; Kitagawa, Nobuyoshi; Tokita, Kenichi; Yamamoto, Soichiro; Seto, Yasuo


    The ion mobility behavior of nineteen chemical warfare agents (7 nerve gases, 5 blister agents, 2 lachrymators, 2 blood agents, 3 choking agents) and related compounds including simulants (8 agents) and organic solvents (39) was comparably investigated by the ion mobility spectrometry instrument utilizing weak electric field linear drift tube with corona discharge ionization, ammonia doping, purified inner air drift flow circulation operated at ambient temperature and pressure. Three alkyl methylphosphonofluoridates, tabun, and four organophosphorus simulants gave the intense characteristic positive monomer-derived ion peaks and small dimer-derived ion peaks, and the later ion peaks were increased with the vapor concentrations. VX, RVX and tabun gave both characteristic positive monomer-derived ions and degradation product ions. Nitrogen mustards gave the intense characteristic positive ion peaks, and in addition distinctive negative ion peak appeared from HN3. Mustard gas, lewisite 1, o-chlorobenzylidenemalononitrile and 2-mercaptoethanol gave the characteristic negative ion peaks. Methylphosphonyl difluoride, 2-chloroacetophenone and 1,4-thioxane gave the characteristic ion peaks both in the positive and negative ion mode. 2-Chloroethylethylsulfide and allylisothiocyanate gave weak ion peaks. The marker ion peaks derived from two blood agents and three choking agents were very close to the reactant ion peak in negative ion mode and the respective reduced ion mobility was fluctuated. The reduced ion mobility of the CWA monomer-derived peaks were positively correlated with molecular masses among structurally similar agents such as G-type nerve gases and organophosphorus simulants; V-type nerve gases and nitrogen mustards. The slope values of the calibration plots of the peak heights of the characteristic marker ions versus the vapor concentrations are related to the detection sensitivity, and within chemical warfare agents examined the slope values for sarin, soman

  9. Biological warfare agents. (United States)

    Pohanka, Miroslav; Kuca, Kamil


    Biological warfare agents are a group of pathogens and toxins of biological origin that can be potentially misused for military or criminal purposes. The present review attempts to summarize necessary knowledge about biological warfare agents. The historical aspects, examples of applications of these agents such as anthrax letters, biological weapons impact, a summary of biological warfare agents and epidemiology of infections are described. The last section tries to estimate future trends in research on biological warfare agents.

  10. Development of the HS-SPME-GC-MS/MS method for analysis of chemical warfare agent and their degradation products in environmental samples. (United States)

    Nawała, Jakub; Czupryński, Krzysztof; Popiel, Stanisław; Dziedzic, Daniel; Bełdowski, Jacek


    After World War II approximately 50,000 tons of chemical weapons were dumped in the Baltic Sea by the Soviet Union under the provisions of the Potsdam Conference on Disarmament. These dumped chemical warfare agents still possess a major threat to the marine environment and to human life. Therefore, continue monitoring of these munitions is essential. In this work, we present the application of new solid phase microextraction fibers in analysis of chemical warfare agents and their degradation products. It can be concluded that the best fiber for analysis of sulfur mustard and its degradation products is butyl acrylate (BA), whereas for analysis of organoarsenic compounds and chloroacetophenone, the best fiber is a co-polymer of methyl acrylate and methyl methacrylate (MA/MMA). In order to achieve the lowest LOD and LOQ the samples should be divided into two subsamples. One of them should be analyzed using a BA fiber, and the second one using a MA/MMA fiber. When the fast analysis is required, the microextraction should be performed by use of a butyl acrylate fiber because the extraction efficiency of organoarsenic compounds for this fiber is acceptable. Next, we have elaborated of the HS-SPME-GC-MS/MS method for analysis of CWA degradation products in environmental samples using laboratory obtained fibers The analytical method for analysis of organosulfur and organoarsenic compounds was optimized and validated. The LOD's for all target chemicals were between 0.03 and 0.65 ppb. Then, the analytical method developed by us, was used for the analysis of sediment and pore water samples from the Baltic Sea. During these studies, 80 samples were analyzed. It was found that 25 sediments and 5 pore water samples contained CWA degradation products such as 1,4-dithiane, 1,4-oxathiane or triphenylarsine, the latter being a component of arsine oil. The obtained data is evidence that the CWAs present in the Baltic Sea have leaked into the general marine environment.

  11. Chemical Warfare Agent Simulants in Gamble’s Fluid: Is the Fluid Toxic? Can It Be Made Safer by Inclusion of Solid Nanocrystalline Metal Oxides?

    Directory of Open Access Journals (Sweden)

    Dennis Karote


    Full Text Available The reactions of chemical warfare agent simulants, 2-chloroethyl ethyl sulfide (2-CEES and di-i-propyl fluoro phosphate (DFP, in fluids have been investigated. Data analyses confirm the major degradation pathway to be hydrolysis of 2-CEES to 2-hydroxyethyl ethyl sulfide, along with minor self-condensation products. Among the three fluids examined, 2-CEES degradation was the fastest in Gamble’s fluid during a 96 h period. Upon addition of Exceptional Hazard Attenuation Materials (EHAMs to 2-CEES containing Gamble’s fluid, degradation was generally improved during the first 24 h period. The 96 h outcome was similar for fluid samples with or without EHAM 2 and EHAM 4. EHAM 1-added fluid contained only one degradation product, 2-nitroethyl ethyl sulfide. DFP degradation was the slowest in Gamble’s fluid, but was enhanced by the addition of EHAMs. FTIR and solid state 31P NMR confirm the destructive adsorption of 2-CEES and DFP by the EHAMs. The results collectively demonstrate that 2-CEES and DFP decompose to various extents in Gamble’s fluid over a 96 h period but the fluid still contains a considerable amount of intact simulant. EHAM 1 appears to be promising for 2-CEES and DFP mitigation while EHAM 2 and EHAM 4 work well for early on concentration reduction of 2-CEES and DFP.

  12. Fate of the chemical warfare agent O-ethyl S-2-diisopropylaminoethyl methylphosphonothiolate (VX) on soil following accelerant-based fire and liquid decontamination. (United States)

    Gravett, M R; Hopkins, F B; Self, A J; Webb, A J; Timperley, C M; Riches, J R


    procedures and analytical methods suitable for investigating accelerant and decontaminant-soaked soil samples are presented. VX and its degradation products and/or impurities were detected under all the conditions studied, demonstrating that accelerant-based fire and liquid-based decontamination and then fire are unlikely to prevent the retrieval of evidence of chemical warfare agent (CWA) testing. This is the first published study of the effects of an accelerant-based fire on a CWA in environmental samples. The results will inform defence and security-based organisations worldwide and support the verification activities of the Organisation for the Prohibition of Chemical Weapons (OPCW), winner of the 2013 Nobel Peace Prize for its extensive efforts to eliminate chemical weapons.

  13. Flying Electronic Warfare Laboratory (United States)

    Federal Laboratory Consortium — FUNCTION: Provides NP-3D aircraft host platforms for Effectiveness of Navy Electronic Warfare Systems (ENEWS) Program antiship missile (ASM) seeker simulators used...

  14. Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DNA damage in rats. (United States)

    Wei, Min; Yamada, Takanori; Yamano, Shotaro; Kato, Minoru; Kakehashi, Anna; Fujioka, Masaki; Tago, Yoshiyuki; Kitano, Mistuaki; Wanibuchi, Hideki


    Diphenylarsinic acid (DPAA), a chemical warfare-related neurotoxic organic arsenical, is present in the groundwater and soil in some regions of Japan due to illegal dumping after World War II. Inorganic arsenic is carcinogenic in humans and its organic arsenic metabolites are carcinogenic in animal studies, raising serious concerns about the carcinogenicity of DPAA. However, the carcinogenic potential of DPAA has not yet been evaluated. In the present study we found that DPAA significantly enhanced the development of diethylnitrosamine-induced preneoplastic lesions in the liver in a medium-term rat liver carcinogenesis assay. Evaluation of the expression of cytochrome P450 (CYP) enzymes in the liver revealed that DPAA induced the expression of CYP1B1, but not any other CYP1, CYP2, or CYP3 enzymes, suggesting that CYP1B1 might be the enzyme responsible for the metabolic activation of DPAA. We also found increased oxidative DNA damage, possibly due to elevated CYP1B1 expression. Induction of CYP1B1 has generally been linked with the activation of AhR, and we found that DPAA activates the aryl hydrocarbon receptor (AhR). Importantly, the promotion effect of DPAA was observed only at a dose that activated the AhR, suggesting that activation of AhR and consequent induction of AhR target genes and oxidative DNA damage plays a vital role in the promotion effects of DPAA. The present study provides, for the first time, evidence regarding the carcinogenicity of DPAA and indicates the necessity of comprehensive evaluation of its carcinogenic potential using long-term carcinogenicity studies.

  15. Diphenylarsinic acid, a chemical warfare-related neurotoxicant, promotes liver carcinogenesis via activation of aryl hydrocarbon receptor signaling and consequent induction of oxidative DAN damage in rats

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Min; Yamada, Takanori; Yamano, Shotaro; Kato, Minoru; Kakehashi, Anna; Fujioka, Masaki; Tago, Yoshiyuki; Kitano, Mistuaki; Wanibuchi, Hideki, E-mail:


    Diphenylarsinic acid (DPAA), a chemical warfare-related neurotoxic organic arsenical, is present in the groundwater and soil in some regions of Japan due to illegal dumping after World War II. Inorganic arsenic is carcinogenic in humans and its organic arsenic metabolites are carcinogenic in animal studies, raising serious concerns about the carcinogenicity of DPAA. However, the carcinogenic potential of DPAA has not yet been evaluated. In the present study we found that DPAA significantly enhanced the development of diethylnitrosamine-induced preneoplastic lesions in the liver in a medium-term rat liver carcinogenesis assay. Evaluation of the expression of cytochrome P450 (CYP) enzymes in the liver revealed that DPAA induced the expression of CYP1B1, but not any other CYP1, CYP2, or CYP3 enzymes, suggesting that CYP1B1 might be the enzyme responsible for the metabolic activation of DPAA. We also found increased oxidative DNA damage, possibly due to elevated CYP1B1 expression. Induction of CYP1B1 has generally been linked with the activation of AhR, and we found that DPAA activates the aryl hydrocarbon receptor (AhR). Importantly, the promotion effect of DPAA was observed only at a dose that activated the AhR, suggesting that activation of AhR and consequent induction of AhR target genes and oxidative DNA damage plays a vital role in the promotion effects of DPAA. The present study provides, for the first time, evidence regarding the carcinogenicity of DPAA and indicates the necessity of comprehensive evaluation of its carcinogenic potential using long-term carcinogenicity studies. - Highlights: • DPAA, an environmental neurotoxicant, promotes liver carcinogenesis in rats. • DPAA is an activator of AhR signaling pathway. • DPAA promoted oxidative DNA damage in rat livers. • AhR target gene CYP 1B1 might be involved in the metabolism of DPAA.

  16. Wipe selection for the analysis of surface materials containing chemical warfare agent nitrogen mustard degradation products by ultra-high pressure liquid chromatography-tandem mass spectrometry. (United States)

    Willison, Stuart A


    Degradation products arising from nitrogen mustard chemical warfare agent were deposited on common urban surfaces and determined via surface wiping, wipe extraction, and liquid chromatography–tandem mass spectrometry detection. Wipes investigated included cotton gauze, glass fiber filter, non-woven polyester fiber and filter paper, and surfaces included several porous (vinyl tile, painted drywall, wood) and mostly non-porous (laminate, galvanized steel, glass) surfaces. Wipe extracts were analyzed by ultra-high pressure liquid chromatography–tandem mass spectrometry (UPLC–MS/MS) and compared with high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) results. An evaluation of both techniques suggests UPLC–MS/MS provides a quick and sensitive analysis of targeted degradation products in addition to being nearly four times faster than a single HPLC run, allowing for greater throughput during a wide-spread release concerning large-scale contamination and subsequent remediation events. Based on the overall performance of all tested wipes, filter paper wipes were selected over other wipes because they did not contain interferences or native species (TEA and DEA) associated with the target analytes, resulting in high percent recoveries and low background levels during sample analysis. Other wipes, including cotton gauze, would require a pre-cleaning step due to the presence of large quantities of native species or interferences of the targeted analytes. Percent recoveries obtained from a laminate surface were 47–99% for all nitrogen mustard degradation products. The resulting detection limits achieved from wipes were 0.2 ng/cm(2) for triethanolamine (TEA), 0.03 ng/cm(2) for N-ethyldiethanolamine (EDEA), 0.1 ng/cm(2) for N-methyldiethanolamine (MDEA), and 0.1 ng/cm(2) for diethanolamine (DEA).

  17. Comparison of latex body paint with wetted gauze wipes for sampling the chemical warfare agents VX and sulfur mustard from common indoor surfaces. (United States)

    Hernon-Kenny, Laura A; Behringer, Deborah L; Crenshaw, Michael D


    Comparison of solvent-wetted gauze with body paint, a peelable surface sampling media, for the sampling of the chemical warfare agents VX and sulfur mustard from nine surfaces was performed. The nine surfaces sampled are those typical of interior public venues and include smooth, rough, porous, and non-porous surfaces. Overall, solvent-wetted gauze (wipes) performed better for the recovery of VX from non-porous surfaces while body paint (BP) performed better for the porous surfaces. The average percent VX recoveries using wipes and BP, respectively, are: finished wood flooring, 86.2%, 71.4%; escalator handrail, 47.3%, 26.7%; stainless steel, 80.5%, 56.1%; glazed ceramic tile, 81.8%, 44.9%; ceiling tile, 1.77%, 13.1%; painted drywall 7.83%, 21.1%; smooth cement, 0.64%, 10.3%; upholstery fabric, 24.6%, 23.1%; unfinished wood flooring, 9.37%, 13.1%. Solvent-wetted gauze performed better for the recovery of sulfur mustard from three of the relatively non-porous surfaces while body paint performed better for the more porous surfaces. The average percent sulfur mustard recoveries using wipes and BP, respectively, are: finished wood flooring, 30.2%, 2.97%; escalator handrail, 4.40%, 4.09%; stainless steel, 21.2%, 3.30%; glazed ceramic tile, 49.7%, 16.7%; ceiling tile, 0.33%, 11.1%; painted drywall 2.05%, 10.6%; smooth cement, 1.20%, 35.2%; upholstery fabric, 7.63%, 6.03%; unfinished wood flooring, 0.90%, 1.74%.

  18. Chemical warfare: Leaf-cutting ants defend themselves and their gardens against parasite attack by deploying antibiotic secreting bacteria. (United States)

    Samuels, Richard Ian; Mattoso, Thalles Cardoso; Moreira, Denise D O


    Leaf-cutting ants are well known for their highly complex social organization, which provides them with a strong defense against parasites invading their colonies. Besides this attribute, these insects have morphological, physiological and structural characteristics further reinforcing the defense of their colonies. With the discovery of symbiotic bacteria present on the integument of leaf-cutting ants, a new line of defense was proposed and considered to be specific for the control of a specialized fungal parasite of the ants' fungus gardens (Escovopsis). However, recent studies have questioned the specificity of the integumental bacteria, as they were also found to inhibit a range of fungi, including entomopathogens. The microbiota associated with the leaf-cutting ant gardens has also been proposed as another level of chemical defense, protecting the garden from parasite invasion. Here we review the chemical defense weaponry deployed by leaf-cutting ants against parasites of their fungus gardens and of the ants themselves.

  19. Evaporation Rates of Chemical Warfare Agents Measured Using 5 CM Wind Tunnels. 2. Munitions Grade Sulfur Mustard From Sand (United States)


    was obtained from the back gate of Cannon AFB, New Mexico , and is a surface sample. Chemical analyses are in Appendix E, and surface area data are...m t*5 ft ft cO o o . a* a* «•! if- 6* s* £ aci/i^iotr- vino *» in K c\\ v " tv O O O) 00 f* tf- (T rf

  20. Rapid Analysis of Chemical Warfare Agents and Their Hydrolysis Products by Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) (United States)


    to diethyl hydrogen phosphate, suggesting that hydrolysis of nerve agents to their initial acids would be significant following autoclaving... toxins and related compounds: state of the art and future prospects. J. Chromatogr. A, 814, 1- 23. [4] Munro, N.B., Talmage, S.S., Griffin, G.D., Waters...Morrissey, K.M. and Durst, H.D. (2000). Trace determination of isopropyl methylphosphonofluoridate (GB) and bis (2-chloroethyl) sulfide (HD) in chemical

  1. Iron oxide functionalized graphene nano-composite for dispersive solid phase extraction of chemical warfare agents from aqueous samples. (United States)

    Chinthakindi, Sridhar; Purohit, Ajay; Singh, Varoon; Tak, Vijay; Goud, D Raghavender; Dubey, D K; Pardasani, Deepak


    Present study deals with the preparation and evaluation of graphene based magnetic nano-composite for dispersive solid phase extraction of Chemical Weapons Convention (CWC) relevant chemicals from aqueous samples. Nano-composite, Fe3O4@SiO2-G was synthesized by covalently bonding silica coated Fe3O4 onto the graphene sheets. Nerve agents (NA), Sulfur mustard (SM) and their non-toxic environmental markers were the target analytes. Extraction parameters like amount of sorbent, extraction time and desorption conditions were optimized. Dispersion of 20 milligram of sorbent in 200mL of water sample for 20min. followed by methanol/chloroform extraction produced average to good recoveries (27-94%) of targeted analytes. Recoveries of real agents exhibited great dependency upon sample pH and ionic strength. Sarin produced maximum recovery under mild acidic conditions (56% at pH 5) while VX demanded alkaline media (83% at pH 9). Salts presence in the aqueous samples was found to be advantageous, raising the recoveries to as high as 94% for SM. Excellent limits of detection (LOD) for sulphur mustard and VX (0.11ngmL(-1) and 0.19ngmL(-1) respectively) proved the utility of the developed method for the off-site analysis of CWC relevant chemicals.

  2. Effective methylation of phosphonic acids related to chemical warfare agents mediated by trimethyloxonium tetrafluoroborate for their qualitative detection and identification by gas chromatography-mass spectrometry. (United States)

    Valdez, Carlos A; Leif, Roald N; Alcaraz, Armando


    The effective methylation of phosphonic acids related to chemical warfare agents (CWAs) employing trimethyloxonium tetrafluoroborate (TMO·BF4) for their qualitative detection and identification by gas chromatography-mass spectrometry (GC-MS) is presented. The methylation occurs in rapid fashion (1 h) and can be conveniently carried out at ambient temperature, thus providing a safer alternative to the universally employed diazomethane-based methylation protocols. Optimization of the methylation parameters led us to conclude that methylene chloride was the ideal solvent to carry out the derivatization, and that even though methylated products can be observed surfacing after only 1 h, additional time was not found to be detrimental but beneficial to the process particularly when dealing with analytes at low concentrations (∼10 μg mL(-1)). Due to its insolubility in methylene chloride, TMO·BF4 conveniently settles to the bottom during the reaction and does not produce additional interfering by-products that may further complicate the GC-MS analysis. The method was demonstrated to successfully methylate a variety of Schedule 2 phosphonic acids, including their half esters, resulting in derivatives that were readily detected and identified using the instrument's spectral library. Most importantly, the method was shown to simultaneously methylate a mixture of the organophosphorus-based nerve agent hydrolysis products: pinacolyl methylphosphonate (PMPA), cyclohexyl methylphosphonate (CyMPA) and ethyl methylphosphonate (EMPA) (at a 10 μg mL(-1) concentration each) in a fatty acid ester-rich organic matrix (OPCW-PT-O3) featured in the 38th Organisation for the Prohibition of Chemical Weapons (OPCW) Proficiency Test. In addition, the protocol was found to effectively methylate N,N-diethylamino ethanesulfonic acid and N,N-diisopropylamino ethanesulfonic acid that are products arising from the oxidative degradation of the V-series agents VR and VX respectively. The

  3. Effective, Facile, and Selective Hydrolysis of the Chemical Warfare Agent VX Using Zr6-Based Metal-Organic Frameworks. (United States)

    Moon, Su-Young; Wagner, George W; Mondloch, Joseph E; Peterson, Gregory W; DeCoste, Jared B; Hupp, Joseph T; Farha, Omar K


    The nerve agent VX is among the most toxic chemicals known to mankind, and robust solutions are needed to rapidly and selectively deactivate it. Herein, we demonstrate that three Zr6-based metal-organic frameworks (MOFs), namely, UiO-67, UiO-67-NH2, and UiO-67-N(Me)2, are selective and highly active catalysts for the hydrolysis of VX. Utilizing UiO-67, UiO-67-NH2, and UiO-67-N(Me)2 in a pH 10 buffered solution of N-ethylmorpholine, selective hydrolysis of the P-S bond in VX was observed. In addition, UiO-67-N(Me)2 was found to catalyze VX hydrolysis with an initial half-life of 1.8 min. This half-life is nearly 3 orders of magnitude shorter than that of the only other MOF tested to date for hydrolysis of VX and rivals the activity of the best nonenzymatic materials. Hydrolysis utilizing Zr-based MOFs is also selective and facile in the absence of pH 10 buffer (just water) and for the destruction of the toxic byproduct EA-2192.

  4. Rethinking Defensive Information Warfare (United States)


    electronic warfare, and special information operations. Defensive information operations ensure timely, accurate, and relevant information access...information and information systems. IA, physical security, OPSEC, counter-deception, counter-psyops, CI, EW, and special information operations. Ensure

  5. Defining cyber warfare

    Directory of Open Access Journals (Sweden)

    Dragan D. Mladenović


    Full Text Available Cyber conflicts represent a new kind of warfare that is technologically developing very rapidly. Such development results in more frequent and more intensive cyber attacks undertaken by states against adversary targets, with a wide range of diverse operations, from information operations to physical destruction of targets. Nevertheless, cyber warfare is waged through the application of the same means, techniques and methods as those used in cyber criminal, terrorism and intelligence activities. Moreover, it has a very specific nature that enables states to covertly initiate attacks against their adversaries. The starting point in defining doctrines, procedures and standards in the area of cyber warfare is determining its true nature. In this paper, a contribution to this effort was made through the analysis of the existing state doctrines and international practice in the area of cyber warfare towards the determination of its nationally acceptable definition.

  6. Development of a gas-cylinder-free plasma desorption/ionization system for on-site detection of chemical warfare agents. (United States)

    Iwai, Takahiro; Kakegawa, Ken; Aida, Mari; Nagashima, Hisayuki; Nagoya, Tomoki; Kanamori-Kataoka, Mieko; Miyahara, Hidekazu; Seto, Yasuo; Okino, Akitoshi


    A gas-cylinder-free plasma desorption/ionization system was developed to realize a mobile on-site analytical device for detection of chemical warfare agents (CWAs). In this system, the plasma source was directly connected to the inlet of a mass spectrometer. The plasma can be generated with ambient air, which is drawn into the discharge region by negative pressure in the mass spectrometer. High-power density pulsed plasma of 100 kW could be generated by using a microhollow cathode and a laboratory-built high-intensity pulsed power supply (pulse width: 10-20 μs; repetition frequency: 50 Hz). CWAs were desorbed and protonated in the enclosed space adjacent to the plasma source. Protonated sample molecules were introduced to the mass spectrometer by airflow through the discharge region. To evaluate the analytical performance of this device, helium and air plasma were directly irradiated to CWAs in the gas-cylinder-free plasma desorption/ionization system and the protonated molecules were analyzed by using an ion-trap mass spectrometer. A blister agent (nitrogen mustard 3) and nerve gases [cyclohexylsarin (GF), tabun (GA), and O-ethyl S-2-N,N-diisopropylaminoethyl methylphosphonothiolate (VX)] in solution in n-hexane were applied to the Teflon rod and used as test samples, after solvent evaporation. As a result, protonated molecules of CWAs were successfully observed as the characteristic ion peaks at m/z 204, 181, 163, and 268, respectively. In air plasma, the limits of detection were estimated to be 22, 20, 4.8, and 1.0 pmol, respectively, which were lower than those obtained with helium plasma. To achieve quantitative analysis, calibration curves were made by using CWA stimulant dipinacolyl methylphosphonate as an internal standard; straight correlation lines (R(2) = 0.9998) of the peak intensity ratios (target per internal standard) were obtained. Remarkably, GA and GF gave protonated dimer ions, and the ratios of the protonated dimer ions to the protonated

  7. Biological warfare agents

    Directory of Open Access Journals (Sweden)

    Duraipandian Thavaselvam


    Full Text Available The recent bioterrorist attacks using anthrax spores have emphasized the need to detect and decontaminate critical facilities in the shortest possible time. There has been a remarkable progress in the detection, protection and decontamination of biological warfare agents as many instrumentation platforms and detection methodologies are developed and commissioned. Even then the threat of biological warfare agents and their use in bioterrorist attacks still remain a leading cause of global concern. Furthermore in the past decade there have been threats due to the emerging new diseases and also the re-emergence of old diseases and development of antimicrobial resistance and spread to new geographical regions. The preparedness against these agents need complete knowledge about the disease, better research and training facilities, diagnostic facilities and improved public health system. This review on the biological warfare agents will provide information on the biological warfare agents, their mode of transmission and spread and also the detection systems available to detect them. In addition the current information on the availability of commercially available and developing technologies against biological warfare agents has also been discussed. The risk that arise due to the use of these agents in warfare or bioterrorism related scenario can be mitigated with the availability of improved detection technologies.

  8. Biological Warfare Agents

    Directory of Open Access Journals (Sweden)

    Dev Vrat Kamboj


    Full Text Available There is a long historic record of use of biological warfare (BW agents by warring countriesagainst their enemies. However, the frequency of their use has increased since the beginningof the twentieth century. World war I witnessed the use of anthrax agent against human beingsand animals by Germans, followed by large-scale field trials by Japanese against war prisonersand Chinese population during world war II. Ironically, research and development in biologicalwarfare agents increased tremendously after the Geneva Protocol, signed in 1925, because ofits drawbacks which were overcome by Biological and Toxin Weapons Convention (BTWC in1972. Biological warfare programme took back seat after the 1972 convention but biologicalagents regained their importance after the bioterrorist attacks of anthrax powder in 2001. In thelight of these attacks, many of which turned out to be hoax, general awareness is required aboutbiological warfare agents that can be used against them. This review has been written highlightingimportant biological warfare agents, diseases caused by them, possible therapies and otherprotection measures.

  9. The Physics of Warfare (United States)

    Giordano, Gerardo


    Recently, I was tasked with the creation and execution of a new themed general education physics class called The Physics of Warfare. In the past, I had used the theme of a class, such as the physics of sports medicine, as a way to create homework and in-class activities, generate discussions, and provide an application to demonstrate that physics…

  10. Electronic Warfare Signature Measurement Facility (United States)

    Federal Laboratory Consortium — The Electronic Warfare Signature Measurement Facility contains specialized mobile spectral, radiometric, and imaging measurement systems to characterize ultraviolet,...

  11. Establishing Cyber Warfare Doctrine

    Directory of Open Access Journals (Sweden)

    Andrew M. Colarik


    Full Text Available Over the past several decades, advances in technology have transformed communications and the ability to acquire, disseminate, and utilize information in a range of environments. Modern societies and their respective militaries have taken advantage of a robust information space through network-centric systems. Because military and commercial operations have increasingly converged, communication and information infrastructures are now high-priority military objectives in times of war. This article examines the theoretical underpinning of current cyber warfare research, what we have learned so far about its application, and some of the emerging themes to be considered; it also postulates the development of a (national cyber warfare doctrine (CWD. An endeavor of this scale requires lots of considerations and preparation for its development if it is to be cooperatively embraced. This article considers why information technology systems and their supporting infrastructures should be considered legitimate military targets in conflicts, and offers several events that support this supposition. In addition, it identifies the various forms of doctrine that will become the basis for developing a CWD, discusses a CWD's possible components, and proposes a national collaborative and discussion framework for obtaining a nation's stakeholder buy-in for such an endeavor.

  12. Cutaneous challenge with chemical warfare agents in the SKH-1 hairless mouse (II): effects of some currently used skin decontaminants (RSDL and Fuller's earth) against liquid sulphur mustard and VX exposure. (United States)

    Taysse, L; Dorandeu, F; Daulon, S; Foquin, A; Perrier, N; Lallement, G; Breton, P


    Using the hairless mouse screening model presented in the companion paper(1) the aim of this study was to assess two skin decontaminating systems: Fuller's earth (FE) and Reactive Skin Decontamination Lotion (RSDL) against two extremely toxic chemical warfare agents that represent a special percutaneous hazard, sulphur mustard (SM) and O-ethyl-S-(2[di-isopropylamino]ethyl)methyl-phosphonothioate (VX). Five minutes after being exposed on the back to either 2 µL of neat sulphur mustard or 50 µ of diluted VX, mice were decontaminated. Both systems were able to reduce blisters 3 days after SM exposure. However, RSDL was found to be more efficient than FE in reducing the necrosis of the epidermis and erosion. In the case of VX exposure, RSDL, whatever the ratio of decontaminant to toxicant used (RSDL 10, 20, 50), was not able to sufficiently prevent the inhibition of plasma cholinesterases taken as a surrogate marker of exposure and toxicity. Only FE reduced significantly the ChE inhibition. Some of these observations are different from our previous results obtained in domestic swine and these changes are thus discussed in the perspective of using SKH-1 hairless mice for the initial in vivo screening of decontaminants.

  13. Rain-Induced Wash-Off of Chemical Warfare Agent (VX) from Foliar Surfaces of Living Plants Maintained in a Surety Hood (United States)


    the environment is influenced by their physical and chemical properties as well as ambient meteorological conditions and the environmental material...testing. Physiologically healthy plants were maintained within the chemical agent surety hood environment (Simini et al., 2016). The temperature within... environment . Commanders who have soldiers under battlefield conditions must be armed with functional information for “Go/No-Go” decisions related to

  14. Airpower Support to Unconventional Warfare (United States)


    supplies to isolated mountain outposts (Trest 2000, 109). The Helio Couriers operated out of small dirt strips, referred to as lima sites, usually... rosa : The O.S.S. and American espionage. New York: Reynal and Hitchcock. AF Special Operations Command white paper. 2007. USAF irregular warfare...Symposium on the role of airpower in counterinsurgency and unconventional warfare: A brief summary of viewpoints. Santa Monica, CA: The RAND

  15. Proceedings of the USAF/NATO Conference on Maintenance of Air Base Operations in a Chemical Warfare Environment Held in Williamsburg, Virginia on August - September 1987 (United States)


    meter area around the system in which no pipes , phone lines, or power lines are present. No communication devices or fixed hard disks are allowed on...Pressure in Suit. Discomfort to the wearer’s eardrums when straightening up from deep knee bends occurred in the prototype suit. The Salty Demo suit...Technical Manager U.S. Army U.S. Navy U.S. Air Force Chemical Division Chemical, Biological Special Projects Grp . CRDEC, Research Dir. Radiological Def

  16. An isomer-specific high-energy collision-induced dissociation MS/MS database for forensic applications: a proof-of-concept on chemical warfare agent markers. (United States)

    Subramaniam, Raja; Östin, Anders; Nygren, Yvonne; Juhlin, Lars; Nilsson, Calle; Åstot, Crister


    Spectra database search has become the most popular technique for the identification of unknown chemicals, minimizing the need for authentic reference chemicals. In the present study, an isomer-specific high-energy collision-induced dissociation (CID) MS/MS spectra database of 12 isomeric O-hexyl methylphosphonic acids (degradation markers of nerve agents) was created. Phosphonate anions were produced by the electrospray ionization of phosphonic acids or negative-ion chemical ionization of their fluorinated derivatives and were analysed in a hybrid magnetic-sector-time-of-flight tandem mass spectrometer. A centre-of-mass energy (E(com)) of 65 eV led to an optimal sequential carbon-carbon bond breakage, which was interpreted in terms of charge remote fragmentation. The proposed mechanism is discussed in comparison with the routinely used low-energy CID MS/MS. Even-mass (odd-electron) charge remote fragmentation ion series were diagnostic of the O-alkyl chain structure and can be used to interpret unknown spectra. Together with the odd-mass ion series, they formed highly reproducible, isomer-specific spectra that gave significantly higher database matches and probability factors (by 1.5 times) than did the EI MS spectra of the trimethylsilyl derivatives of the same isomers. In addition, ionization by negative-ion chemical ionization and electrospray ionization resulted in similar spectra, which further highlights the general potential of the high-energy CID MS/MS technique.

  17. ISIL's Hybrid Warfare in Syria & Iraq

    DEFF Research Database (Denmark)

    Sørensen, Heine


    The case study specifically seeks to answer the following problem statement: Does ISIL qualify as an actor using hybrid warfare and if so what characterizes their particular use of this type of warfare? Based on an analysis of ISIL’s warfare from August 2012 to August 2016 the chapter argues, tha...

  18. Evaluation on the capability of a skin decontaminatant PF2009 to inactivate chemical warfare agents%皮肤洗消剂PF2009对化学毒剂的消毒作用

    Institute of Scientific and Technical Information of China (English)

    刘红岩; 刘艳芹; 应莺; 林京玉; 王伊文; 左国民; 朱海燕; 钟玉绪


    Objective To evaluate the capability of skin decontamination lotion PF2009 to decontaminate chemical warfare agents. Methods The remnant of chemical warfare agents, soman (GD), VX or sulfur mustard(HD), was measured with gas phase chromatography or T-135 method after being mixed with PF2009 for indicated time. The mixtures of PF2009 with GD, VX at a molar ratio of 10:1 was measured by the main agent were administered to rabbits through intraperitoneal injection. 6 days later, the activity of acetylcholinesterase(AChE) in animal blood was determined with the method of DTNB. The survival rate was calculated after counting the living and died rabbits. The mixtures of PF2009 with HD were administered to rabbit skin. The area of injured skin was measured. Histochemical method was employed to observe the pathological change in the injured skin. Results Remnant of GD or VX could not be detected after being mixed with PF2009 at a volume ratio of 150 for 10 min. Under the same mixing condition, decontaminated HD increased from 80% to 94% when prolonging the incubation time from 10 to 60 min. Rabbits were intraperitoneally administered with the mixture of PF2009 with GD at a dose of 454 or 9.00 mg/kg or VX at a dose 3.34 mg/kg. No animals died in PF2009 group. In contrast, all rabbits died in lotion matrix control group during the 6 days' observation. 90% activity of AChE in blood was maintained for PF2009 group when compared with that for un-administered normal animals. The mixture of PF2009 with HD was administered to the rabbit skin at a dose of 1 mg/ cm2. The damage of skin was much lighter in PF2009 group than in lotion matrix control group when being evaluated with the area value of injured skin and histochemical staining. Conclusion The skin decontamination lotion PF2009 is effective in inactivating chemical warfare agents in vitro.%目的 通过检测皮肤洗消剂PF2009对化学毒剂的体外消毒效率,对皮肤洗消剂PF2009的消毒效果进行评价.方法

  19. The fragmentation pathways of protonated Amiton in the gas phase: towards the structural characterisation of organophosphorus chemical warfare agents by electrospray ionisation tandem mass spectrometry. (United States)

    Ellis-Steinborner, Simon; Ramachandran, Aravind; Blanksby, Stephen J


    Amiton (O,O-diethyl-S-[2-(diethylamino)ethyl] phosphorothiolate), otherwise known as VG, is listed in schedule 2 of the Chemical Weapons Convention (CWC) and has a structure closely related to VX (O-ethyl-S-(2-diisopropylamino)ethylmethylphosphonothiolate). Fragmentation of protonated VG in the gas phase was performed using electrospray ionisation ion trap mass spectrometry (ESI-ITMS) and revealed several characteristic product ions. Quantum chemical calculations provide the most probable structures for these ions as well as the likely unimolecular mechanisms by which they are formed. The decomposition pathways predicted by computation are consistent with deuterium-labeling studies. The combination of experimental and theoretical data suggests that the fragmentation pathways of VG and analogous organophosphorus nerve agents, such as VX and Russian VX, are predictable and thus ESI tandem mass spectrometry is a powerful tool for the verification of unknown compounds listed in the CWC.

  20. Background chemistry for chemical warfare agents and decontamination processes in support of delisting waste streams at the U.S. Army Dugway Proving Ground, Utah

    Energy Technology Data Exchange (ETDEWEB)

    Rosenblatt, D.H.; Small, M.J.; Kimmell, T.A.; Anderson, A.W.


    The State of Utah, Department of Environmental Quality (DEQ), Division of Solid and Hazardous Waste (DSHW), has declared residues resulting from the demilitarization, treatment, cleanup, and testing of military chemical agents to be hazardous wastes. These residues have been designated as corrosive, reactive, toxic, and acute hazardous (Hazardous Waste No. F999). The RCRA regulations (40 Code of Federal Regulations [CFR] 260-280), the Utah Administrative Code (R-315), and other state hazardous waste programs list specific wastes as hazardous but allow generators to petition the regulator to {open_quotes}delist,{close_quotes} if it can be demonstrated that such wastes are not hazardous. The U.S. Army Test and Evaluation Command (TECOM) believes that certain categories of F999 residues are not hazardous and has obtained assistance from Argonne National Laboratory (Argonne) to make the delisting demonstration. The objective of this project is to delist chemical agent decontaminated residues resulting from materials testing activities and to delist a remediation residue (e.g., contaminated soil). To delist these residues, it must be demonstrated that the residues (1) do not contain hazardous quantities of the listed agents; (2) do not contain hazardous quantities of constituents listed in 40 CFR Part 261, Appendix VIII; (3) do not exhibit other characteristics that could define the residues as hazardous; and (4) do not fail a series of acute toxicity tests. The first phase will focus on a subset of the F999 wastes generated at the U.S. Army Dugway Proving Ground (DPG), where the Army tests the effects of military chemical agents and agent-decontamination procedures on numerous military items. This effort is identified as Phase I of the Delisting Program. Subsequent phases will address other DPG chemical agent decontaminated residues and remediation wastes and similar residues at other installations.

  1. The Different Sensitive Behaviors of a Hydrogen-Bond Acidic Polymer-Coated SAW Sensor for Chemical Warfare Agents and Their Simulants

    Directory of Open Access Journals (Sweden)

    Yin Long


    Full Text Available A linear hydrogen-bond acidic (HBA linear functionalized polymer (PLF, was deposited onto a bare surface acoustic wave (SAW device to fabricate a chemical sensor. Real-time responses of the sensor to a series of compounds including sarin (GB, dimethyl methylphosphonate (DMMP, mustard gas (HD, chloroethyl ethyl sulphide (2-CEES, 1,5-dichloropentane (DCP and some organic solvents were studied. The results show that the sensor is highly sensitive to GB and DMMP, and has low sensitivity to HD and DCP, as expected. However, the sensor possesses an unexpected high sensitivity toward 2-CEES. This good sensing performance can’t be solely or mainly attributed to the dipole-dipole interaction since the sensor is not sensitive to some high polarity solvents. We believe the lone pair electrons around the sulphur atom of 2-CEES provide an electron-rich site, which facilitates the formation of hydrogen bonding between PLF and 2-CEES. On the contrary, the electron cloud on the sulphur atom of the HD molecule is offset or depleted by its two neighbouring strong electron-withdrawing groups, hence, hydrogen bonding can hardly be formed.

  2. Toxicology and pharmacology of the chemical warfare agent sulfur mustard - a review. Final technical report, 29 September 1994-31 January 1995

    Energy Technology Data Exchange (ETDEWEB)

    Dacre, J.C.; Beers, R.; Goldman, M.


    Sulfur mustard is a poisonous chemical agent which exerts a local action on the eyes, skin and respiratory tissue with subsequent systemic action on the nervous, cardiac, and digestive and endocrine systems in man and laboratory animals causing lacrimation, malaise, anorexia, salivation, respiratory distress, vomiting, hyperexcitability, cardiac distress, and death. Sulfur mustard is a cell poison which causes disumption and impairment of a variety of cellular activities which are dependent upon a very specific integral relationship. These cytotoxic effects are manifested in widespread metabolic disturbances whose variable characteristics are observed in enzymatic deficiencies, vesicant action, abnormal mitotic activity and cell division, bone marrow disruption, disturbances in hematopoietic activity and systemic poisoning. Indeed, mustard gas readily combines with various components of the cell such as amino acids, amines and proteins. Sulfur mustard has been shown to be mainly a lung carcinogen in various test animal species; this effect is highly dependent of size of the dose and the route of exposure. In the human, there is evidence of cancers of the respiratory tract in men exposed to mustard gas. Mutagenicity of sulfur mustard, due to the strong alkylating activity, has been reported to occur in many different species of animals, plants, bacteria, and fungi. There is no strong evidence that sulfur mustard is a teratogen but much further research, with particular emphasis on maternal and fetal toxicity, is needed and recommended.

  3. Evolutionary Models of Irregular Warfare (United States)


    G. (2010) Decentralize, adapt and cooperate. Nature 465:292-293. Sagarin, R. (2012) Learning From the Octopus : How Secrets from Nature Can Help Us...because the concepts map on to important features of modern irregular warfare. For example, small-scale behaviors are increasingly thought to

  4. The Anatomy of Counterinsurgency Warfare

    DEFF Research Database (Denmark)

    Ringsmose, Jens; Pedersen, Kenneth

    Since the beginning of the new millennium, the West has been increasingly involved in a tiresome and rather particular type of conflict: insurgency warfare. The bloody and shocking terrorist attacks on New York and Washington in September 2001 marked the beginning of a new era, and the introducti...

  5. Measurement of breakthrough volumes of volatile chemical warfare agents on a poly(2,6-diphenylphenylene oxide)-based adsorbent and application to thermal desorption-gas chromatography/mass spectrometric analysis. (United States)

    Kanamori-Kataoka, Mieko; Seto, Yasuo


    To establish adequate on-site solvent trapping of volatile chemical warfare agents (CWAs) from air samples, we measured the breakthrough volumes of CWAs on three adsorbent resins by an elution technique using direct electron ionization mass spectrometry. The trapping characteristics of Tenax(®) TA were better than those of Tenax(®) GR and Carboxen(®) 1016. The latter two adsorbents showed non-reproducible breakthrough behavior and low VX recovery. The specific breakthrough values were more than 44 (sarin) L/g Tenax(®) TA resin at 20°C. Logarithmic values of specific breakthrough volume for four nerve agents (sarin, soman, tabun, and VX) showed a nearly linear correlation with the reciprocals of their boiling points, but the data point of sulfur mustard deviated from this linear curve. Next, we developed a method to determine volatile CWAs in ambient air by thermal desorption-gas chromatography (TD-GC/MS). CWA solutions that were spiked into the Tenax TA(®) adsorbent tubes were analyzed by a two-stage TD-GC/MS using a Tenax(®) TA-packed cold trap tube. Linear calibration curves for CWAs retained in the resin tubes were obtained in the range between 0.2pL and 100pL for sarin, soman, tabun, cyclohexylsarin, and sulfur mustard; and between 2pL and 100pL for VX and Russian VX. We also examined the stability of CWAs in Tenax(®) TA tubes purged with either dry or 50% relative humidity air under storage conditions at room temperature or 4°C. More than 80% sarin, soman, tabun, cyclohexylsarin, and sulfur mustard were recovered from the tubes within 2 weeks. In contrast, the recoveries of VX and Russian VX drastically reduced with storage time at room temperature, resulting in a drop to 10-30% after 2 weeks. Moreover, we examined the trapping efficiency of Tenax TA(®) adsorbent tubes for vaporized CWA samples (100mL) prepared in a 500mL gas sampling cylinder. In the concentration range of 0.2-2.5mg/m(3), >50% of sarin, soman, tabun, cyclohexylsarin, and HD were


    Directory of Open Access Journals (Sweden)

    Dan-Iulian VOITAȘEC


    Full Text Available According to the Declaration of Saint Petersburg of 1868 “the only legitimate object which States should endeavor to accomplish during war is to weaken the military forces of the enemy”. Thus, International Humanitarian Law prohibits or limits the use of certain means and methods of warfare. The rapid development of technology has led to the emergence of a new dimension of warfare. The cyber aspect of armed conflict has led to the development of new means and methods of warfare. The purpose of this paper is to study how the norms of international humanitarian law apply to the means and methods of cyber warfare.

  7. Cyber warfare building the scientific foundation

    CERN Document Server

    Jajodia, Sushil; Subrahmanian, VS; Swarup, Vipin; Wang, Cliff


    This book features a wide spectrum of the latest computer science research relating to cyber warfare, including military and policy dimensions. It is the first book to explore the scientific foundation of cyber warfare and features research from the areas of artificial intelligence, game theory, programming languages, graph theory and more. The high-level approach and emphasis on scientific rigor provides insights on ways to improve cyber warfare defense worldwide. Cyber Warfare: Building the Scientific Foundation targets researchers and practitioners working in cyber security, especially gove

  8. Electronic warfare target location methods

    CERN Document Server

    Poisel, Richard


    Describing the mathematical development underlying current and classical methods of geolocating electronic systems that are emitting, this newly revised and greatly expanded edition of a classic Artech House book offers practical guidance in electronic warfare target location. The Second Edition features a wealth of additional material including new chapters on time delay estimation, direction finding techniques, and the MUSIC algorithm. This practical resource provides you with critical design information on geolocation algorithms, and establishes the fundamentals of existing algorithms as a

  9. Rethinking Cultural Influences on Warfare (United States)


    education system. Within military education, culture is approached as a dimension of warfare that must be operationalized at all levels of war by...capabilities and habits acquired by man as a member of society.”37 Geert Hofstede , a social psychologist, defines culture as “the collective programming...Putnam and Sons, 1920), 1. 38 Geert Hofstede , Communication Between Cultures eds. L.A. Samovar and R.E. Porter. (Belmont: Wadsworth, 1984), 51. 13

  10. Irregular Warfare: A Selected Bibliography (United States)


    Airman’s Assessment of FM 3-24 and the Case for Developing Truly Joint COIN Doctrine. Maxwell Air Force Base: U.S. Air University, 2007. 111pp. ( Pinnell , Daniel A. The Tenets of Airpower in an Insurgent Environment. Strategy Research Project. Carlisle...Non-Kinetic Capabilities for Irregular Warfare: Four Case Studies. Alexandria: Institute for Defense Analyses, Joint Advanced Warfighting Program

  11. Undersea Warfare Academic Group Home Page



    Collected from the Internet Archive "Wayback machine". The Undersea Warfare Curriculum educates officers in the engineering fundamentals, physical principles and analytical concepts that govern operational employment of undersea warfare (USW) sensors and weapons systems. Program is interdisciplinary and integrates; mathematics, physics, acoustics, electrical engineering, oceanography, operations analysis, human factors, computer science and meteorology.

  12. Airship Renaissance: Considerations for Operational Warfare (United States)


    FINAL 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Airship Renaissance : Considerations for Operational Warfare 5a. CONTRACT...Airship Renaissance : Considerations for Operational Warfare by Daniel W. Smith III Major, United States Air Force A paper submitted...resources needed now on the battlefield…to get more intelligence, surveillance, and reconnaissance assets into the theatre .” 5 Recognizing budget

  13. The Art of Aerial Warfare (United States)


    the  Strait  of  Gibraltar   from  North  Africa  during  the Spanish Civil War. 11 FAIRCHILD PAPER A Comparison of Aerial Warfare to Land... Hitler , for example, the United States cannot assume that Nazi aggression would have  evaporated  instantly. Although  Hitler himself profoundly affected


    Directory of Open Access Journals (Sweden)

    Laurian GHERMAN


    Full Text Available The paper is focused on changes occurred in military organizations in Information Age. During Industrial Age the military structure of forces evolved according with principles of decomposition, specialization, hierarchy, optimization, deconfliction, centralized planning, and decentralized execution. But now the solutions based upon Industrial Age assumptions and practices will break down and fail in the Information Age. This will happen no matter how well intentioned, hardworking, or dedicated the leadership and the force are. Two key force capabilities needed by Information Age militaries are interoperability and agility. Both interoperability and agility are provided by Network centric warfare theory of war.

  15. Information warfare technologies in political discourse

    Directory of Open Access Journals (Sweden)

    Karpova Anna Yu.


    Full Text Available We attempt to examine the technology of «information warfare» in this paper. The dominant theme of the paper is that the outcome of the information warfare is important not only for the future of a state itself but for the future of the world balance of forces. The main task of geopolitical actors in information warfare is to introduce ideas corresponding to their interests into mass consciousness. All participants of political conflicts have common features in technologies of Information warfare. The information anomie is the indicator of the great geopolitical actors’ personified interests on the stage of «information warfare» - the process resulted in destroying the communicative line: report-information understanding and disrupting the social order in society. In this paper authors describe the following Information Warfare technologies: "Political volcano" technology; "SPIN" technology; "Widening media resource" technology; "specific gravity" technology; "Cold War 2.0" technology and Information cleaningup technology. It is assumed that in the future there will be new instructions on applying technologies of information warfare. To impart perspective to the paper we consider examples, opinions and trends.

  16. Grid architecture model of network centric warfare

    Institute of Scientific and Technical Information of China (English)

    Yan Tihua; Wang Baoshu


    NCW(network centric warfare) is an information warfare concentrating on network. A global network-centric warfare architecture with OGSA grid technology is put forward, which is a four levels system including the user level, the application level, the grid middleware layer and the resource level. In grid middleware layer, based on virtual hosting environment, a BEPL4WS grid service composition method is introduced. In addition, the NCW grid service model is built with the help of Eclipse-SDK-3.0.1 and Bpws4j.

  17. Cyber Warfare: New Character with Strategic Results (United States)


    defense ( CND ).”7 Thus cyber warfare is distinguished from cyber criminal acts based upon its coercive nature to attain a strategic end, whereas...CNA and CND . Conceptually, CNA effects “range from disrupting the adversary’s electronic systems and what operations they enable (communications...or self-destruct.”10 The second component of cyber warfare seeks to eliminate or minimize the risk of the first. The role of CND is to defend

  18. Finding Lawrence recruiting talent for unconventional warfare


    Mourouzis, Michael G.


    Approved for public release; distribution is unlimited. From Francis Marion's guerrilla war against the British to advising the resistance against the Nazis and Japanese, the United States has depended on unconventional warfare (UW) as a component of national defense. Today, the U.S. Army Special Forces (SF) is the premiere unconventional warfare unit in the U.S. military. With a smaller Army and increasing missions, SF must expand its recruiting efforts. This thesis analyzes the recruitme...

  19. A Dialectic for Network Centric Warfare (United States)


    Giffin, 2003; Borgu , 2003; Kaufman, 2004). For example, from a standpoint of Popperian methodological falsificationism (Popper, 1934), Reid and...focused term network-centric warfare has common favor ( Borgu , 2003) despite the organisational decree to use the term ‘network centric warfare...Commonwealth Department of Defence, June. Borgu , A., (2003), “The Challenges and Limitations of Network Centric Warfare”, Presented at NCW: Improving ADF

  20. Intrafamily and intragenomic conflicts in human warfare (United States)


    Recent years have seen an explosion of multidisciplinary interest in ancient human warfare. Theory has emphasized a key role for kin-selected cooperation, modulated by sex-specific demography, in explaining intergroup violence. However, conflicts of interest remain a relatively underexplored factor in the evolutionary-ecological study of warfare, with little consideration given to which parties influence the decision to go to war and how their motivations may differ. We develop a mathematical model to investigate the interplay between sex-specific demography and human warfare, showing that: the ecology of warfare drives the evolution of sex-biased dispersal; sex-biased dispersal modulates intrafamily and intragenomic conflicts in relation to warfare; intragenomic conflict drives parent-of-origin-specific patterns of gene expression—i.e. ‘genomic imprinting’—in relation to warfare phenotypes; and an ecological perspective of conflicts at the levels of the gene, individual, and social group yields novel predictions as to pathologies associated with mutations and epimutations at loci underpinning human violence. PMID:28228515

  1. Hybrid Warfare: A Military Revolution or Revolution in Military Affairs? (United States)


    warfare intersect and blend to create a new form of warfare. This thesis uses the Williamson Murray and McGregor Knox definitions of Military...irregular warfare intersect and blend to create a new form of warfare. This thesis uses the Williamson Murray and McGregor Knox definitions of...understand new concepts. Douglas C Lovelace. Director Strategic Studies Institute has this insight to offer regarding the importance of

  2. Biological warfare, bioterrorism, and biocrime. (United States)

    Jansen, H J; Breeveld, F J; Stijnis, C; Grobusch, M P


    Biological weapons achieve their intended target effects through the infectivity of disease-causing infectious agents. The ability to use biological agents in warfare is prohibited by the Biological and Toxin Weapon Convention. Bioterrorism is defined as the deliberate release of viruses, bacteria or other agents used to cause illness or death in people, but also in animals or plants. It is aimed at creating casualties, terror, societal disruption, or economic loss, inspired by ideological, religious or political beliefs. The success of bioterroristic attempts is defined by the measure of societal disruption and panic, and not necessarily by the sheer number of casualties. Thus, making only a few individuals ill by the use of crude methods may be sufficient, as long as it creates the impact that is aimed for. The assessment of bioterrorism threats and motives have been described before. Biocrime implies the use of a biological agent to kill or make ill a single individual or small group of individuals, motivated by revenge or the desire for monetary gain by extortion, rather than by political, ideological, religious or other beliefs. The likelihood of a successful bioterrorist attack is not very large, given the technical difficulties and constraints. However, even if the number of casualties is likely to be limited, the impact of a bioterrorist attack can still be high. Measures aimed at enhancing diagnostic and therapeutic capabilities and capacities alongside training and education will improve the ability of society to combat 'regular' infectious diseases outbreaks, as well as mitigating the effects of bioterrorist attacks.

  3. Guiding Warfare to Reach Sustainable Peace

    DEFF Research Database (Denmark)

    Vestenskov, David; Drewes, Line

    The conference report Guiding Warfare to Reach Sustainable Peace constitutes the primary outcome of the conference It is based on excerpts from the conference presenters and workshop discussions. Furthermore, the report contains policy recommendations and key findings, with the ambition of develo......The conference report Guiding Warfare to Reach Sustainable Peace constitutes the primary outcome of the conference It is based on excerpts from the conference presenters and workshop discussions. Furthermore, the report contains policy recommendations and key findings, with the ambition...... of developing best practices in the education and implementation of IHL in capacity building of security forces....

  4. US Army Special Warfare. Its Origins: Psychological and Unconventional Warfare, 1941-1952 (United States)


    sug- F P _ _ 6 PSYCHOLOGICAL WARFARE IN WORLD WAR I! gestion of a single agency which would serve as a clearinghouse for all intelligence, as well as...organizations, communications, demoli- tions, organization and training of civilians for guerrilla warfare, para- chute jumping, and amphibious...General Bolte, Director, P&O, was reluctant to endorse this latter sug- gestion , indicating, "as he had indicated from time to time at other points

  5. Modern Warfare From the Colombian Perspective (United States)


    Involved into a Fourth Generation, 1. 7 M-19 Movimiento revolucionario 19 de abril. Former insurgency group. 8 Alberto Pinzon Sanchez. En Causa Propia...a Fourth Generation. Alberto Pinzon Sanchez. En Causa Propia. Mao Tse Tung. On Guerrilla Warfare, Baltimore, Md.: Nautical

  6. Agricultural Warfare and Bioterrorism using Invasive Species (United States)

    The chapter on Agricultural Warfare and Bioterrorism using Invasive Species is part of the book titled Pest Management and Phytosanitary Trade Barriers authored by Neil Heather (Australia) and Guy Hallman. The chapter attempts to briefly put the topic into context with phytosanitation. It presents...

  7. Russia’s Approach to Cyber Warfare (United States)


    psychological operations, and information operations. • In keeping with traditional Soviet notions of battling constant threats from abroad and within...playing a greater role in conventional Russian military operations. Although the Russian military has been slow to embrace cyber for both structural and...theorists, is a holistic concept that includes computer network operations, electronic warfare, psychological operations, and information operations.3

  8. Working on warfare-related sites. Review after 15 years and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Schneider, U. [Umweltberatung und Planung, Kassel (Germany)


    Fifteen years ago, in 1988, in connection with the Second International TNO/BMFT-Congress for the first time sites contaminated due to armaments production were mentioned, caused by the results of the first systematic investigation of a former explosives production plant in Hessisch Lichtenau. The authors referred to another 72 large chemical armament production plants in the FRG and 39 in the GDR. At the Third International TNO/BMFT-Congress in 1990 the complex of problems were substantiated and at the same time more topics were added. The Federal Government of Germany named the following areas suspected of being warfare-related contaminated sites: former production plants, ammunition depots, defusing sites, demolition areas and firing ranges, disassembly plants and intermediate and final storage plants for conventional and chemical combat agents. Soil, water and air pollution could be caused by the following products: explosives, chemical warfare agents, incendiaries, smoke agents, propellants, additives, primary and waste products and residues from the destruction of combat agents. In 1995 the Federal Environmental Agency (UBA) presented the results of the national survey showing that there are 3240 suspected contaminated sites. In 1995 also began the soil clean-up at the warfare-related contaminated sites Stadtallendorf and Hessisch Lichtenau. 8 respectively 10 years after the beginning of the systematic investigations the first contaminated soil was removed and treated in a thermal plant. In the run-up several R and D projects funded by the Federal Government were carried out (Stadtallendorf: MOSAL = Model Remediation of Contaminated Sites, Hessisch Lichtenau: Joint project Biological Remediation of Warfare-Related Contamination). At these sites basics were worked out and technologies were put to the test which can be used for the remediation of other sites. (orig.)

  9. Unconventional Warfare: A Mission Metamorphosis for the 21st Century? (United States)


    brigadier general and publish several more noted works on Mao and revolutionary warfare. See Samuel B. Giffith, Mao Tse-Tung on Guerrilla Warfare (New...and propagators of the faith. The bibles (in English translation) are Mao Tse-tung on Guerrilla Warfare by Brigadier General Samuel B. Griffith...Barnett, B. Hugh Tovar , and Richard H. Schultz eds., Special Operations in US Strategy (Washington, D.C.: US Government Printing Office, 1984), 2. 58

  10. Computational models of intergroup competition and warfare.

    Energy Technology Data Exchange (ETDEWEB)

    Letendre, Kenneth (University of New Mexico); Abbott, Robert G.


    This document reports on the research of Kenneth Letendre, the recipient of a Sandia Graduate Research Fellowship at the University of New Mexico. Warfare is an extreme form of intergroup competition in which individuals make extreme sacrifices for the benefit of their nation or other group to which they belong. Among animals, limited, non-lethal competition is the norm. It is not fully understood what factors lead to warfare. We studied the global variation in the frequency of civil conflict among countries of the world, and its positive association with variation in the intensity of infectious disease. We demonstrated that the burden of human infectious disease importantly predicts the frequency of civil conflict and tested a causal model for this association based on the parasite-stress theory of sociality. We also investigated the organization of social foraging by colonies of harvester ants in the genus Pogonomyrmex, using both field studies and computer models.

  11. Electronic Warfare in Army Models - A Survey. (United States)



  12. Africa: Irregular Warfare on the Dark Continent (United States)


    only to the mighty Amazon for 13 Alexander, Africa: Irregular Warfare on the Dark Continent tropical forests. The demand for hardwood lumber is...were decades in the making. Prolonged drought , desertification, and overpopulation are among the primary reasons for the fighting, which breaks down...go to lengths to differentiate themselves from other indigenous people.120 General repression of the Tuaregs was exacerbated by repeated droughts

  13. Mapping the Spread of Mounted Warfare

    Directory of Open Access Journals (Sweden)

    Peter Turchin


    Full Text Available Military technology is one of the most important factors affecting the evolution of complex societies. In particular, mounted warfare, the use of horse-riders in military operations, revolutionized war as it spread to different parts of Eurasia and Africa during the Ancient and Medieval eras, and to the Americas during the Early Modern period. Here we use a variety of sources to map this spread.

  14. Impact of Using a High Surface Area Solid Phase Micro Extraction Device and Fast Gas Chromatography Heating Rates in the Sampling and Analysis of Trace Level Chemical Warfare Agents and CWA-Like Compounds (United States)


    rest of the inner diameter of the column is filled with inert carrier gas (the mobile phase), often helium or hydrogen . Chemical compounds are...Sample of Liquid CWA-Degradation Product The VX degradation compound, 2-(diisopropylaminoethyl)ethyl sulfide (2-DES) was diluted in methylene chloride...demonstrated separation of CWA mixture components ranging in molecular weight from m/z 140 (sarin) to 466 (T2 toxin ) with a field-portable GC/MS system

  15. Ending the scourge of chemical weapons

    Energy Technology Data Exchange (ETDEWEB)

    Brin, J.


    After more than 20 years of arduous negotiations, representatives from 131 countries gathered in Paris in January to sign a treaty banning the development, production, and transfer to other countries of chemical-warfare agents and their means of delivery. The treaty - called the Chemical Weapons Convention, or CWC - complements the more limited Geneva Protocol of 1925, which bans the use of toxic chemicals in warfare. When the CWC enters into force in about two years, it will prohibit the manufacture for military purposes of lethal chemicals such as sulfur mustard, which causes painful skin blistering and lung damage, and nerve agents, which cause rapid death by interfering with the transmission of nerve impulses. The goal is to eliminate from the earth this particularly inhumane form of warfare. The paper discusses facets of the treaty, especially the verification challenge with its inspection on demand features. Short accompanying pieces discuss classifying chemicals and the destruction of chemical weapons under the CWC.

  16. The Cycle of Warfare - Analysis of an Analytical Model

    DEFF Research Database (Denmark)

    Jensen, Mikkel Storm


    The abstract has the title: “The Cycle of Warfare - Analysis of an Analytical Model” The Cycle of Warfare is an analytical model designed to illustrate the coherence between the organization, doctrine and technology of a military entity and the influence of the surrounding society as expressed...

  17. Dirty Fighting: How to Counter Total Warfare Mentality (United States)


    DIRTY FIGHTING: HOW TO COUNTER TOTAL WARFARE MENTALITY A thesis presented to the Faculty of the U.S. Army Command Counter Total Warfare Mentality Approved by: , Thesis Committee Chair LTC Sandra J. Sanchez, MBA , Member Marlyn R. Pierce...

  18. Cyberspace Warfare: A New DoD Core Mission Area (United States)


    Century thief breaking into files, not into metal safes. The mysterious group Anonymous has struck again, with a warning, this is just the 5 Starr and...cyberspace warfare aside as science fiction hogwash, and accept the risks of the possible. The evolution of warfare has evolved over time, but the nature of

  19. Electronic warfare receivers and receiving systems

    CERN Document Server

    Poisel, Richard A


    Receivers systems are considered the core of electronic warfare (EW) intercept systems. Without them, the fundamental purpose of such systems is null and void. This book considers the major elements that make up receiver systems and the receivers that go in them.This resource provides system design engineers with techniques for design and development of EW receivers for modern modulations (spread spectrum) in addition to receivers for older, common modulation formats. Each major module in these receivers is considered in detail. Design information is included as well as performance tradeoffs o

  20. Microwave receivers with electronic warfare applications

    CERN Document Server

    Tsui, James


    This book by the author of Digital Techniques for Wideband Receivers willbe like no other one on your book shelf as the definitive word on electronicwarfare (EW) receiver design and performance. Whether you are an EWscientist involved in the test and evaluation of EW receivers or a designerof RWR's and other EW-related receivers, Microwave Receivers withElectronic Warfare Applications is a handy reference through which you canperfect your technical art. Lucidly written, this book is a treatise on EWreceivers that is relevant to you if you are just looking for a top-levelinsight into EW receive

  1. Hybrid Warfare: Preparing for Future Conflict (United States)


    Fukuyama , Francis . “At the ‘End of History’ Still Stands Democracy.” The Wall Street Journal, 6 June 2014. is cultural instead of political (in the traditional Clausewitzian sense). 15 Hoffman is referring to Francis Fukuyama’s idea of “the end of...history,” as argued in his 1989 essay and subsequent book. Fukuyama first published an essay titled “The End of History” in the National Interest in


    CERN Multimedia

    Medical Service


    It is reminded that all persons who use chemicals must inform CERN's Chemistry Service (TIS-GS-GC) and the CERN Medical Service (TIS-ME). Information concerning their toxicity or other hazards as well as the necessary individual and collective protection measures will be provided by these two services. Users must be in possession of a material safety data sheet (MSDS) for each chemical used. These can be obtained by one of several means : the manufacturer of the chemical (legally obliged to supply an MSDS for each chemical delivered) ; CERN's Chemistry Service of the General Safety Group of TIS ; for chemicals and gases available in the CERN Stores the MSDS has been made available via EDH either in pdf format or else via a link to the supplier's web site. Training courses in chemical safety are available for registration via HR-TD. CERN Medical Service : TIS-ME :73186 or Chemistry Service : TIS-GS-GC : 78546

  3. Biodegradation of Organophosphate Chemical Warfare Agents by Activated Sludge (United States)


    0.5 g H3BO3, 0.3 g ZnSO4·7H2O, 0.24 g MnCl2·4H2O, 0.14 g CuSO4 ·5H2O, 0.06 g KI, 0.06 g Na2MoO4· 2H2O , 0.06 g CoCl2·6H2O, 0.06 g NiCl2·6H2O, and 0.06 g...g CaCl2· 2H2O , 0.6675 g KH2PO4 and 20mL of a trace element solution, adapted from Hesselmann et al. (1999). The trace element solution consisted of...the following (per liter of deionized water): 5.46 g citric acid, 4.0 g hippuric acid, 0.72 g Na3NTA· 2H2O , 0.3 g Na3EDTA·4H2O, 3.0 g FeCl3·6H2O

  4. Reactivity of Dual-Use Decontaminants with Chemical Warfare Agents (United States)


    Analytical Reference Material grade HD, pinacolyl methyl phosphonofluoridate (soman or GD), and O- ethyl S-(2-diisopropylaminoethyl) methyl...concentrate Benzyl alcohol, ethanolamine, polyethylene glycol trimethylnonyl ether , decyl(sulfophenoxy)benzene- sulfonic acid, disodium salt, water...monohexyl ether , ammonium hydroxide, Water Readily available mixture of solvent chemistries in a basic pH Table 3. Preparation of Decontaminant

  5. Strategy in the Robotic Age: A Case for Autonomous Warfare (United States)


    question legal, ethical , and moral standings about lethal robotic systems. Foreign policy options may be altered because new military options become... ROBOTIC AGE: A CASE FOR AUTONOMOUS WARFARE by Barry S. Scott September 2014 Thesis Advisor: Donald Abenheim Co-Advisor: James Wirtz THIS...Master’s Thesis 4. TITLE AND SUBTITLE STRATEGY IN THE ROBOTIC AGE: A CASE FOR AUTONOMOUS WARFARE 5. FUNDING NUMBERS 6. AUTHOR(S) Barry S. Scott

  6. Littoral Combat Ship Open Ocean Anti-Submarine Warfare (United States)


    COVERED Capstone 4. TITLE AND SUBTITLE LITTORAL COMBAT SHIP OPEN OCEAN ANTI-SUBMARINE WARFARE 5. FUNDING NUMBERS 6. AUTHOR(S) 311-124O/Team LCS...Life cycle cost LCCE Life cycle cost estimate LCS Littoral combat ship LHA Landing ship, helicopter assault LHD Landing ship, unlimited LITTORAL COMBAT SHIP OPEN OCEAN ANTI- SUBMARINE WARFARE by Team LCS 311-124O June 2014 Capstone Advisors: John Green Dan

  7. Helicopters in Irregular Warfare: Algeria, Vietnam, and Afghanistan (United States)


    the political group associated with the Algerian nationalist independence movement GALAT Groupement d’ Aviation Légère de l’Armée de Terre ...unique from most conflicts because the expeditionary forces’ parent country rarely perceives an existential threat.19 The lack of perceived threat...dominance rarely guarantees success in irregular warfare.22 Instead, success in irregular warfare requires synergy between government and military efforts

  8. Depth vs. breadth: talent management for special warfare


    Krebs, William K.


    Approved for public release; distribution is unlimited This thesis presents recommendations for improving officer talent management for Special Warfare units. Success in this complex human domain demands that key planners and commanders of a Special Warfare campaign operate with a long-term perspective, a depth of expertise, and a strong network of relationships. However, on any given day in a U.S. Army Special Forces Group, the preponderance of field grade officers are in their first year...

  9. Fourth Generation Warfare and Its Impact on the Army (United States)


    In 1989, the authors of an article entitled, "The Changing Face of War: Into the Fourth Generation ," offered a glimpse of the future rooted in the...decline of the West in a world rife with cultural conflicts and the powerful influences of a form of cultural Marxism known as political correctness...were combining in America to create conditions for a new generation of warfare. Their vision included a form of warfare that bypassed the military

  10. Chemical Decontaminant Testing (United States)


    any other provision of law, no person shall be subject to any penalty for failing to comply with a collection of information if it does not display...Some test methods for efficacy require the use of CWAs and decontaminants. 15. SUBJECT TERMS decontamination; chemical warfare agent; CWA...contaminant in samples from contact samplers , coupons, rinsate, or other samples. MS, GC or LC, FID, FPD, or equivalents. ±15 percent of the mass of

  11. Ge{sup 4+} doped TiO{sub 2} for stoichiometric degradation of warfare agents

    Energy Technology Data Exchange (ETDEWEB)

    Stengl, Vaclav, E-mail: [Department of Solid State Chemistry, Institute of Inorganic Chemistry AS CR v.v.i., 250 68 Rez (Czech Republic); Grygar, Tomas Matys [Department of Solid State Chemistry, Institute of Inorganic Chemistry AS CR v.v.i., 250 68 Rez (Czech Republic); Oplustil, Frantisek; Nemec, Tomas [Military Technical Institute of Protection Brno, Veslarska 230, 628 00 Brno (Czech Republic)


    Highlights: Black-Right-Pointing-Pointer We prepared nanodisperse Ge{sup 4+} doped titania by a novel synthesis method. Black-Right-Pointing-Pointer Synthesis does not involve organic solvents, organometallics nor thermal processes. Black-Right-Pointing-Pointer The prepared materials are efficient in removal of chemical warfare agents. Black-Right-Pointing-Pointer Ge{sup 4+} doping improves rate of removal of soman and agent VX by TiO{sub 2}. - Abstract: Germanium doped TiO{sub 2} was prepared by homogeneous hydrolysis of aqueous solutions of GeCl{sub 4} and TiOSO{sub 4} with urea. The synthesized samples were characterized by X-ray diffraction, scanning electron microscopy, EDS analysis, specific surface area (BET) and porosity determination (BJH). Ge{sup 4+} doping increases surface area and content of amorphous phase in prepared samples. These oxides were used in an experimental evaluation of their reactivity with chemical warfare agent, sulphur mustard, soman and agent VX. Ge{sup 4+} doping worsens sulphur mustard degradation and improves soman and agent VX degradation. The best degree of removal (degradation), 100% of soman, 99% of agent VX and 95% of sulphur mustard, is achieved with sample with 2 wt.% of germanium.

  12. The World War Two Allied Economic Warfare: The Case of Turkish Chrome Sales


    ÖNSOY, Murat


    Economic character of "modern warfare" is too important to be underestimated. In the Economic Warfare belligerents attempt to reduce the war capacity of the enemy through various methods. In World War II crushing down the German war production and economy was the main target of the British Ministry of Economic Warfare. For Germany, one of the many ways of overcoming the British Economic Warfare was to trade with the neutral countries that had land connection to the Third Reich. Turkey was one...

  13. Chemical munitions dumped at sea (United States)

    Edwards, Margo; Bełdowski, Jacek


    Modern chemical warfare is a byproduct of the industrial revolution, which created factories capable of rapidly producing artillery shells that could be filled with toxic chemicals such as chlorine, phosgene and mustard agent. The trench warfare of World War I inaugurated extensive deployments of modern chemical weapons in 1915. Concomitantly, the need arose to dispose of damaged, captured or excess chemical munitions and their constituents. Whereas today chemical warfare agents (CWA) are destroyed via chemical neutralization processes or high-temperature incineration in tandem with environmental monitoring, in the early to middle 20th century the options for CWA disposal were limited to open-air burning, burial and disposal at sea. The latter option was identified as the least likely of the three to impact mankind, and sea dumping of chemical munitions commenced. Eventually, the potential impacts of sea dumping human waste were recognized, and in 1972 an international treaty, the Convention on the Prevention of Marine Pollution by Dumping of Wastes and Other Matter, was developed to protect the marine environment from pollution caused by the dumping of wastes and other matter into the ocean. By the time this treaty, referred to as the London Convention, was signed by a majority of nations, millions of tons of munitions were known to have been disposed throughout the world's oceans.

  14. Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development (United States)


    ARL-TN-0779 ● SEP 2016 US Army Research Laboratory Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and...Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development by Neal Tesny Sensors and Electron Devices Directorate...TITLE AND SUBTITLE Electronic Warfare Closed Loop Laboratory (EWCLL) Antenna Motor Software and Hardware Development 5a. CONTRACT NUMBER 5b

  15. Numerical simulation of RCS for carrier electronic warfare airplanes

    Directory of Open Access Journals (Sweden)

    Yue Kuizhi


    Full Text Available This paper studies the radar cross section (RCS of carrier electronic warfare airplanes. Under the typical naval operations section, the mathematical model of the radar wave’s pitch angle incidence range analysis is established. Based on the CATIA software, considering dynamic deflections of duck wing leading edge flaps, flaperons, horizontal tail, and rudder, as well as aircraft with air-to-air missile, anti-radiation missile, electronic jamming pod, and other weapons, the 3D models of carrier electronic warfare airplanes Model A and Model B with weapons were established. Based on the physical optics method and the equivalent electromagnetic flow method, by the use of the RCSAnsys software, the characteristics of carrier electronic warfare airplanes’ RCS under steady and dynamic flights were simulated under the UHF, X, and S radar bands. This paper researches the detection probability of aircraft by radars under the condition of electronic warfare, and completes the mathematical statistical analysis of the simulation results. The results show that: The Model A of carrier electronic warfare airplane is better than Model B on stealth performance and on discover probability by radar detection effectively.

  16. History of biological warfare and bioterrorism. (United States)

    Barras, V; Greub, G


    Bioterrorism literally means using microorganisms or infected samples to cause terror and panic in populations. Bioterrorism had already started 14 centuries before Christ, when the Hittites sent infected rams to their enemies. However, apart from some rare well-documented events, it is often very difficult for historians and microbiologists to differentiate natural epidemics from alleged biological attacks, because: (i) little information is available for times before the advent of modern microbiology; (ii) truth may be manipulated for political reasons, especially for a hot topic such as a biological attack; and (iii) the passage of time may also have distorted the reality of the past. Nevertheless, we have tried to provide to clinical microbiologists an overview of some likely biological warfare that occurred before the 18th century and that included the intentional spread of epidemic diseases such as tularaemia, plague, malaria, smallpox, yellow fever, and leprosy. We also summarize the main events that occurred during the modern microbiology era, from World War I to the recent 'anthrax letters' that followed the World Trade Center attack of September 2001. Again, the political polemic surrounding the use of infectious agents as a weapon may distort the truth. This is nicely exemplified by the Sverdlovsk accident, which was initially attributed by the authorities to a natural foodborne outbreak, and was officially recognized as having a military cause only 13 years later.

  17. Ethical Considerations of Computer Network Attack in Information Warfare (United States)


    attack/destruction, and special information operations (SIO). CNA and the other methods of offensive IO represent the incorporation of information...psychological operations, electronic warfare, physical attack and/or destruction, and special information operations, and could include computer computer networks to record information sent over them. 41 special information operations. Information operations that by their sensitive nature

  18. Anti-submarine warfare with continuously active sonar

    NARCIS (Netherlands)

    Vossen, R. van; Beerens, S.P.; Spek, E. van der


    Existing surveillance sonar systems for anti-submarine warfare (ASW) use a pulsed sonar deployed at a low duty cycle. Continuously active sonar (CAS) is of special interest since the technique could provide better detection performance than conventional pulsed sonar, and it will provide the operator

  19. Public Discussion of Nuclear Warfare: A Time for Hope. (United States)

    Cooper, Martha

    Anti-nuclear discourse, which peaked in 1981-82, signaled an emergence of public discourse on the nuclear warfare issue. During the development of the original atomic bomb, public discussion of the issue was severely restricted, but immediately after the bombing of Hiroshima and Nagasaki, discourse on the subject increased. During the Cold War…

  20. Trends in underwater warfare : From an underwater acoustics perspective

    NARCIS (Netherlands)

    Ort, C.M.; Driessen, F.P.G.


    Technological developments concerning underwater systems for Anti Submarine Warfare (ASW) and Mine Counter Measures (MCM) are directed at optimally countering the underwater threat in the near future. Countering the existing underwater threat is already extremely difficult, but there are several tre

  1. Employing U.S. Information Operations Against Hybrid Warfare Threats (United States)


    activities” ( CEMA ), which is a combination of Cyber and Electronic Warfare.115 However, the relationship between cyber and EW must be carefully considered...generating effects by themselves, as well as serving as a delivery means for MISO. The focus of CEMA may be as much to support combat operations

  2. Simulating cyber warfare and cyber defenses: information value considerations (United States)

    Stytz, Martin R.; Banks, Sheila B.


    Simulating cyber warfare is critical to the preparation of decision-makers for the challenges posed by cyber attacks. Simulation is the only means we have to prepare decision-makers for the inevitable cyber attacks upon the information they will need for decision-making and to develop cyber warfare strategies and tactics. Currently, there is no theory regarding the strategies that should be used to achieve objectives in offensive or defensive cyber warfare, and cyber warfare occurs too rarely to use real-world experience to develop effective strategies. To simulate cyber warfare by affecting the information used for decision-making, we modify the information content of the rings that are compromised during in a decision-making context. The number of rings affected and value of the information that is altered (i.e., the closeness of the ring to the center) is determined by the expertise of the decision-maker and the learning outcome(s) for the simulation exercise. We determine which information rings are compromised using the probability that the simulated cyber defenses that protect each ring can be compromised. These probabilities are based upon prior cyber attack activity in the simulation exercise as well as similar real-world cyber attacks. To determine which information in a compromised "ring" to alter, the simulation environment maintains a record of the cyber attacks that have succeeded in the simulation environment as well as the decision-making context. These two pieces of information are used to compute an estimate of the likelihood that the cyber attack can alter, destroy, or falsify each piece of information in a compromised ring. The unpredictability of information alteration in our approach adds greater realism to the cyber event. This paper suggests a new technique that can be used for cyber warfare simulation, the ring approach for modeling context-dependent information value, and our means for considering information value when assigning cyber

  3. FOA Information from the Research Institute of Swedish National Defence on Electronic Warfare (FOA Orientar om Electronic Warfare), (United States)


    modified. If it is appears as if the psychological It is hardly likely. however. known that the opponent has a warfare element involved there- that the most...34 . -roadeatla - ".-Rhdar Raa -* * - cldignsl Toi~loieey aft u comunication , ntavigation -ctionl Examples of applications Radar bands FroquaP" UMI 0.1

  4. Health risk assessment for chemical exposures of military interest

    NARCIS (Netherlands)

    Langenberg, J.P.; Polhuijs, M.; Sijbranda, T.


    Participation in military operations is accompanied by health hazards resulting from exposure to chemical substances from natural and anthropogenic sources. Historically, focus on toxicological risks has been on the health effects of exposure to chemical warfare agents (CW A). In recent years the aw

  5. Stuxnet and Cyber-Warfare (1/2)

    CERN Document Server

    CERN. Geneva


    The first part of the lecture is devoted to the description of the Stuxnet worm, the first cyber-weapon whose existence has been made public, discovered in 2010 and targeting a specific industrial control system; the worm is responsible for the damaging of many centrifuges at an uranium enrichment facility, with the goal of sabotaging Iran's nuclear program. In the second part, the main features of cyber-warfare in conflict and pre-conflict activities will be discussed and compared to the conventional warfare domains, with also a general view at the international political debate on this topic. Check the web site, an organisation that seeks a world free of nuclear weapons and other weapons of mass destruction.   NB! All Academic Training lectures are recorded and are publicly available. There is no live webcast.

  6. Stuxnet and Cyber-Warfare (2/2)

    CERN Document Server

    CERN. Geneva


    The first part of the lecture is devoted to the description of the Stuxnet worm, the first cyber-weapon whose existence has been made public, discovered in 2010 and targeting a specific industrial control system; the worm is responsible for the damaging of many centrifuges at an uranium enrichment facility, with the goal of sabotaging Iran's nuclear program. In the second part, the main features of cyber-warfare in conflict and pre-conflict activities will be discussed and compared to the conventional warfare domains, with also a general view at the international political debate on this topic.   Check the web site, an organisation that seeks a world free of nuclear weapons and other weapons of mass destruction. The lecturer invites comments via email to NB! All Academic Training lectures are recorded and are publicly available. There is no live webcast.

  7. Russian and Chinese Information Warfare: Theory and Practice (United States)


    Integral neurolinguistic programming •Placing essential programs into the conscious or sub- conscious mind •Subconscious suggestions that modify human...Generators of special rays •Optical systems • Neurolinguistic programming •Computer psychotechnology •The mass media •Audiovisual effects •Special effects...Information Warfare: Theory and Practice 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e

  8. Abraham Guillen: A Relevant Theory for Contemporary Guerrilla Warfare (United States)


    guerrilla warfare. Biography Abraham Guillén was born in Guadalajara, Spain on 13 March 1913 and grew up in a peasant family that struggled to make a...Mao’s theory failed in the Philippines in 1954, Malaysia in 1960, and Thailand by 1970.47 Insurgencies influenced by Che’s theory fared even worse...legitimate and criminal business enterprises. The internet provides access to a wealth of information useful in planning attacks, virtual

  9. Just War and Postmodern Warfare: A German Case Study (United States)


    unjust actions through intervention, guerrilla warfare, terrorism and other aspects of war. To analyze Michael Walzer’s theory of just and unjust ...power meld well with Walzer’s just and unjust war theory and serve a piece of postmodern equation; however, Wolff’s analysis of German foreign policy...between foreign military forces. Therefore, senior leaders must grapple with organizational considerations as well as postmodern challenges and

  10. Enterprises as Inquiring Systems with Implications for Information Warfare (United States)


    defined as the “integrated employment of the core capabilities of electronic warfare, computer network operations, psychological operations, military...comprehension (also explicitly included in Figure 3). The entire spectrum of deception, psychological operations, and all means to impact human-centered...with the same input data (other than ground truth) via different channels and that data must be consistent within itself. The belief in empiricism to

  11. The Enemy Below: Preparing Ground Forces for Subterranean Warfare (United States)


    can endanger the lives of U.S. forces and render mechanical breaching tools inoperable. Air blowers can be used as a hasty means to ventilate a... Penguin Books, 1996). 179 Tom Mangold, The Tunnels of Cu Chi (New York, NY: Random House, 1985). 147 6. A Historical Analysis of Tunnel Warfare and... Penguin Group, 1996. 157 Lester, W. G., & Ali, A. J. “Underground Combat: Stereophonic Blasting, tunnel Rats, and the Soviet-Afghan War.” Engineer

  12. China's Use of Cyber Warfare: Espionage Meets Strategic Deterrence



    This article presents three reasons for states to use cyber warfare and shows that cyberspace is—and will continue to be—a decisive element in China's strategy to ascend in the international system. The three reasons are: deterrence through infiltration of critical infrastructure; military technological espionage to gain military knowledge; and industrial espionage to gain economic advantage. China has a greater interest in using cyberspace offensively than other actors, such as the United St...

  13. USMC Electronic Warfare 2025: Trading Expertise for Advanced Technology (United States)


    airborne electronic warlare during the transition period away from legacy equipment. EA-6B pilots and Electroilic Countermeasures Officers ( ECMOs ...Electronic Warfare (EW) capability. As an EA-6B Electronic Countenneasures Officer ( ECMO ), I anticipate that both the United States Marine Corps and all... ECMOs . An increased workload for Radio Battalion will have the same effect that the assumption of an additional function of Marine aviation will have on

  14. Built to Outlast: Operational Approaches to Hybrid Warfare (United States)


    this approach lies between the nature of “aggressor forces” since MACV visualized an idealized form of conventional warfare to maximize the Army’s...conventional counteroffensive, with Westmoreland claiming that Johnson “ignored the maxim that when the enemy is hurting, you don’t diminish the...something I can put into the computer. Don’t give me your poetry .”194 This trend towards linearization and uniform solutions extended to MACV and

  15. Characterizing and Exploring the Implications of Maritime Irregular Warfare (United States)


    recapture-ship-held-by-somali-pirates/19626852/ Gutman, Roy, Banana Diplomacy: The Making of American Policy in Nicaragua, 1981–1987, New York: Simon...Joint Special Operations Task Force–Philippines Public Affairs, “JSOTF-P Fact Sheet ,” April 1, 2009. Joint Warfighting Center, Irregular Warfare...Department of State, Bureau of Western Hemisphere Affairs, “Civilian Contractors and U.S. Military Personnel Supporting Plan Colombia,” fact sheet

  16. Constitution aims to bring an end to health economy warfare. (United States)

    Harding, Mary-Louise; Martin, Daniel


    A rough new constitution is being drawn up for the NHS in a bid to prevent health economies sliding into bitter 'Bradford-style' warfare in the era of foundations trusts and payment by results. The rules of engagement are part of a package of measures designed to rescue some of the government's flagship reforms amid warnings from audit chiefs on the impact of PbR.

  17. Electronic Warfare:Issues and Challenges for Emitter Classification

    Directory of Open Access Journals (Sweden)

    Manish Gupta


    Full Text Available Electronic warfare (EW is an important capability that provides advantage to defence forces over their adversaries. Defence forces gather tactical intelligence through EW sensors, which provide the means to counter hostile actions of enemy forces. Functions of an EW system is threat detection and the area surveillance so as to determine the identity of surrounding emitters. Emitter classification system identifies possible threats by analysing intercepted signals. Problem of identifying emitters based on its intercepted signal characteristics is a challenging problem in electronic warfare studies. Major issues and challenges for emitter classification such as drifting of emitter parameters due to aging, operational characteristic of an emitter, i.e., same emitter can operate on multiple bands and multiple pulse repetition frequencies (PRFs are highlighted. A novel approach based on some well-known statistical methods, e.g., regression analysis, hypothesis testing, and discriminent analysis is proposed. The effectiveness of the proposed approach has been tested over ELINT (Electronic Intelligence data and illustrated using simulation data. The proposed approach can play a solution for wide variety of problems in emitter classification in electronic warfare studies.Defence Science Journal, 2011, 61(3, pp.228-234, DOI:

  18. 15 CFR Supplement No. 1 to Part 742 - Nonproliferation of Chemical and Biological Weapons (United States)


    ... Biological Weapons No. Supplement No. 1 to Part 742 Commerce and Foreign Trade Regulations Relating to...—Nonproliferation of Chemical and Biological Weapons Note: Exports and reexports of items in performance of...: (i) Equipment (for producing chemical weapon precursors and chemical warfare agents) described...

  19. Deactivating Chemical Agents Using Enzyme-Coated Nanofibers Formed by Electrospinning (United States)


    January 2012 4. TITLE AND SUBTITLE DEACTIVATING CHEMICAL AGENTS USING ENZYME- COATED NANOFIBERS FORMED BY ELECTROSPINNING 5a. CONTRACT NUMBER 5b...298 (Rev. 8-98) Prescribed by ANSI Std. Z39.18 MATS COATINGS ELECTROSPINNING CHEMICAL WARFARE...This page intentionally left blank 1 Deactivating Chemical Agents Using Enzyme- Coated Nanofibers formed by Electrospinning D

  20. History of the Chemical Warfare Service in World War II. Biological Warfare Research in the United States, Volume 2 (United States)


    Direotor: ; O m 4 Dr# Carl A> Bnmdly (Services for all Senior Pathologist personnel "paid by Regional Poultry Research Laboratory Tlar...paper pulp . The detoxified toxin was then mixed in a 100-gailon stainless steel tank, to ensure uniformity of product end expedite safe testing of the...a vacuum evaporator, and an Oliver filter were used to harvest the yield. Efforts to separate the agent material from its broth culture by means

  1. Electronic Warfare: Rethinking the Importance of Its Role In Military Operations (United States)


    electronic warfare support (ES). Electronic attack utilizes the radiation or re- radiation of electromagnetic energy, directed energy, electromagnetic ... electromagnetic energy, directed energy, or anti- radiation weapons to attack enemy personnel or facilities in order to degrade or destroy his... Electromagnetic Preparedness for Advanced Combat organization. USSTRATCOM also employs electronic warfare experts in its non-kinetic operations staff. The

  2. Cyber Warfare: China’s Strategy to Dominate in Cyber Space (United States)


    Revolution.‖ 64Jason Fritz, ―How China will use cyber warfare to leapfrog in military competitiveness,‖ Culture Mandala : The Bulletin of the Centre for East...cyber warfare to leapfrog in military competitiveness.‖ Culture Mandala : The Bulletin of the Centre for East-West Culture and Economic Studies 8 no. 1

  3. The Effects of CW (Chemical Warfare)-Related Chemicals on Social Behavior and Performance (United States)


    the effects of two other stimulants, methamphetamine and methylphenidate , the animals maintained the "scallop" in the FI response curve, indicating that...d-amphetamine and methylphenidate (Beatty, Dodge, Dodge, White, and Panksepp, 1962). Beatty, ot al, Suggest that the activation of catecholamine...injection in baboon. National Institute of Drua Abuse Monograph in Science, 1983ý, 43, 1215-131. Grossman, E. M. Some methodologi~al issues in the conduct

  4. Toxin warfare agents:recognition molecules and drugs for control%生物毒素战剂:检测识别分子与防治药物

    Institute of Scientific and Technical Information of China (English)



    There are various types of toxins in nature. However, these toxins. which are characterized by the ready availability, easy production and high toxicity, are likely biological warfare agents. Toxin warfare agents are different from traditional bacterial and viral agents or from chemical warfare agents in that they pose a great threat because of their diverse potency and the lack of efficacious drugs. Therefore, it is quite important to develop specific. sensitive recognition molecules for detection of toxins and drugs against intoxication caused by toxin agents. This review focuses on advances in recognition molecules of toxins and some drugs used as prevention and treatment hased on the characteristics of toxin warfare agents .%自然界中存在着种类繁多的毒素物质,但最有可能用作战剂的是那些获取方便、制备容易、毒性强、施放后可致人死亡或失能的毒素.毒素战剂既不同于传统的细菌、病毒战剂,也不同于化学毒剂,其最大的威胁来自它的高毒性及缺乏有效的治疗手段.因此,发展毒素战剂的检测识别分子与防治药物就显得尤为重要.本文讨论了生物毒素战剂相关概念、特征,重点综述了毒素战剂的检测识别分子与防治药物研究进展.

  5. Cybersecurity protecting critical infrastructures from cyber attack and cyber warfare

    CERN Document Server

    Johnson, Thomas A


    The World Economic Forum regards the threat of cyber attack as one of the top five global risks confronting nations of the world today. Cyber attacks are increasingly targeting the core functions of the economies in nations throughout the world. The threat to attack critical infrastructures, disrupt critical services, and induce a wide range of damage is becoming more difficult to defend against. Cybersecurity: Protecting Critical Infrastructures from Cyber Attack and Cyber Warfare examines the current cyber threat landscape and discusses the strategies being used by governments and corporatio

  6. China's Use of Cyber Warfare: Espionage Meets Strategic Deterrence

    Directory of Open Access Journals (Sweden)

    Magnus Hjortdal


    Full Text Available This article presents three reasons for states to use cyber warfare and shows that cyberspace is—and will continue to be—a decisive element in China's strategy to ascend in the international system. The three reasons are: deterrence through infiltration of critical infrastructure; military technological espionage to gain military knowledge; and industrial espionage to gain economic advantage. China has a greater interest in using cyberspace offensively than other actors, such as the United States, since it has more to gain from spying on and deterring the United States than the other way around. The article also documents China's progress in cyber warfare and shows how it works as an extension of its traditional strategic thinking and the current debate within the country. Several examples of cyber attacks traceable to China are also presented. This includes cyber intrusions on a nuclear arms laboratory, attacks on defense ministries (including the Joint Strike Fighter and an airbase and the U.S. electric grid, as well as the current Google affair, which has proved to be a small part of a broader attack that also targeted the U.S. Government. There are, however, certain constraints that qualify the image of China as an aggressive actor in cyberspace. Some believe that China itself is the victim of just as many attacks from other states. Furthermore, certain actors in the United States and the West have an interest in overestimating China's capabilities in cyberspace in order to maintain their budgets.

  7. Evanescent planar waveguide detection of biological warfare simulants (United States)

    Sipe, David M.; Schoonmaker, Kenneth P.; Herron, James N.; Mostert, Michael J.


    An evanescent planar waveguide Mark 1.5 instrument was used to detect simulants of biological warfare agents; ovalbumin (OV), MS2 bacteriophage, BG, and Erwinia herbicola (EH). Polyclonal tracer antibodies were labeled with the fluorescent dye, Cy5. Discrete bands of polyclonal capture antibodies were immobilized to a polystyrene planar waveguide with molded integral lenses. An ST-6 CCD camera was used for detection. OV. MS2 and BG were detected in a simultaneous 3 by 3 array; with a total of nine measurements within 6 minutes. EH was analyzed in a separate array. Results were evaluate dat the US Army Joint Field Trials V, at the Dugway Proving Grounds. Over a 10 day period, 32 unknown samples were analyzed daily for each simulant. Detection limits: OV 10 ng/ml, MS2 107 pfu/ml, BG 105 cfu/ml. EH was detectable at 5 X 105 cfu/ml. Overall false positives were 3.0 percent. Therefore, the Mark 1.5 instrument, with a parallel array of detectors, evanescent flourescent excitation, and CCD imaging provides for rapid, sensitive, and specific detection of biological warfare agent simulants.

  8. Optimizing Armed Forces Capabilities for Hybrid Warfare – New Challenge for Slovak Armed Forces

    Directory of Open Access Journals (Sweden)

    Peter PINDJÁK


    Full Text Available The paper deals with the optimization of military capabilities of the Slovak Armed Forces for conducting operations in a hybrid conflict, which represents one of the possible scenarios of irregular warfare. Whereas in the regular warfare adversaries intend to eliminate the centers of gravity of each other, most often command and control structures, in irregular conflicts, the center of gravity shifts towards the will and cognitive perception of the target population. Hybrid warfare comprises a thoroughly planned combination of conventional military approaches and kinetic operations with subversive, irregular activities, including information and cyber operations. These efforts are often accompanied by intensified activities of intelligence services, special operation forces, and even mercenary and other paramilitary groups. The development of irregular warfare capabilities within the Slovak Armed Forces will require a progressive transformation process that may turn the armed forces into a modern and adaptable element of power, capable of deployment in national and international crisis management operations.

  9. Missed Opportunity? Was Iran s Green Movement an Unconventional Warfare Option? (United States)


    UW options. UW doctrinal research remains primarily guerrilla warfare based with less emphasis on diplomacy , information, and economics activities... French intelligence sources claim Iran produced more low-enriched uranium than previously believed. April 2009 – Iranian President Ahmadinejad

  10. The Third World War? In The Cyberspace. Cyber Warfare in the Middle East.

    Directory of Open Access Journals (Sweden)



    Full Text Available This article aims to provide a brief and comprehensive introduction to the issue of cyber warfare and to display the recent development in this area. Geographically, it focuses on the Middle East region, since the vast majority of the most important recent cyber attacks appeared just in there or were connected to it. The first part of the article tries to define the key notion of cyber warfare, compares it to the standard warfare and presents different types of cyber weapons that are known today. The second part points out examples of the most striking recent cyber attacks and uses them as evidences to demonstrate today's importance and dissemination of cyber warfare. Finally, the article sums up pros and cons of the cyber weapons and, in view of these, predicts a significant increase in their use in any future war conflicts.

  11. ‘Lest we forget’*: a veteran and son share a ‘warfare tourism’ experience


    Fallon, Paul; Robinson, Peter


    Warfare tourism’ represents an increasingly significant dimension of contemporary tourism. This paper provides a fresh perspective on participation in ‘warfare tourism’ by investigating the behaviour and experiences of a living veteran and his son returning to two theatres of war in which the veteran had served in the Royal Navy during the Second World War. Active interviews with the two family members were used to gather rich data regarding the two extended trips, which had been funded by ‘H...

  12. Enhanced formulations for neutralization of chemical, biological and industrial toxants (United States)

    Tucker, Mark D [Albuqueque, NM


    An enhanced formulation and method of making that neutralizes the adverse health effects of both chemical and biological compounds, especially chemical warfare (CW) and biological warfare (BW) agents, and toxic industrial chemicals. The enhanced formulation according to the present invention is non-toxic and non-corrosive and can be delivered by a variety of means and in different phases. The formulation provides solubilizing compounds that serve to effectively render the chemical and biological compounds, particularly CW and BW compounds, susceptible to attack, and at least one reactive compound that serves to attack (and detoxify or kill) the compound. The formulation includes at least one solubilizing agent, a reactive compound, a bleaching activator and water.

  13. Book Review: Conquest in Cyberspace: National Security and Information Warfare

    Directory of Open Access Journals (Sweden)

    Gary C. Kessler


    Full Text Available Libicki, M.C. (2007. Conquest in Cyberspace: National Security and Information Warfare. New York: Cambridge University Press. 323 pages, ISBN: 978-0-521-69214-4 (paper, US$80Reviewed by Gary C. Kessler (gary.kessler@champlain.eduMany books -- and even movies ("Live Free or Die Hard" -- are based upon the premise of an impending information war. In these scenarios -- made all too plausible by the increased frequency with which we read about and experience major information security incidents -- a Bad Guy exploits known computer security vulnerabilities in order to control major national infrastructures via the Internet so as to reap financial, economic, and/or personal power.(see PDF for full review


    Directory of Open Access Journals (Sweden)

    Gheorghe MINCULETE


    Full Text Available The military joint operations of the future are characterized by large concentrations of forces and conventional means on the directions that permit the exploitation of the technological superiority and the manifestation of the offensive spirit of the commanders of the joint operation force groups. Having in mind the fact that the relation between the combatant forces and the logistic ones will shift more and more in favour of the latter, the aforementioned operations will be usually supported by modern flexible logistic structures. The constituted force groups will have a significant joint force character, ensuring superior quality of the troops’ combat training, both at individual level and collective level of units and large units. The current article presents innovative aspects of focused logistics, adapted for the modern warfare, which should be designed and achieved in order to increase the operational potential of the joint force groups.

  15. Agroterrorism, Biological Crimes, and Biological Warfare Targeting Animal Agriculture

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Terry M.; Logan-Henfrey, Linda; Weller, Richard E.; Kellman, Brian


    There is a rising level of concern that agriculture might be targeted for economic sabotage by terrorists. Knowledge gathered about the Soviet Union biological weapons program and Iraq following the Gulf War, confirmed that animals and agricultural crops were targets of bioweapon development. These revelations are particularly disturbing in light of the fact that both countries are States Parties to the Biological and Toxin Weapons Convention that entered into force in 1975. The potential for misusing biotechnology to create more virulent pathogens and the lack of international means to detect unethical uses of new technologies to create destructive bioweapons is of increasing concern. Disease outbreaks, whether naturally occurring or intentionally, involving agricultural pathogens that destroy livestock and crops would have a profound impact on a country's infrastructure, economy and export markets. This chapter deals with the history of agroterrorism, biological crimes and biological warfare directed toward animal agriculture, specifically, horses, cattle, swine, sheep, goats, and poultry.

  16. Spectroscopic investigations of surface deposited biological warfare simulants (United States)

    Barrington, Stephen J.; Bird, Hilary; Hurst, Daniel; McIntosh, Alastair J. S.; Spencer, Phillippa; Pelfrey, Suzanne H.; Baker, Matthew J.


    This paper reports a proof-of-principle study aimed at discriminating biological warfare (BW) simulants from common environmental bacteria in order to differentiate pathogenic endospores in situ, to aid any required response for hazard management. We used FTIR spectroscopy combined with multivariate analysis; FTIR is a versatile technique for the non-destructive analysis of a range of materials. We also report an evaluation of multiple pre-processing techniques and subsequent differences in cross-validation accuracy of two pattern recognition models (Support Vector Machines (SVM) and Principal Component - Linear Discriminant Analysis (PC-LDA)) for two classifications: a two class classification (Gram + ve spores vs. Gram -ve vegetative cells) and a six class classification (bacterial classification). Six bacterial strains Bacillus atrophaeus, Bacillus thuringiensis var. kurstaki, Bacillus thuringiensis, Escherichia coli, Pantaeoa agglomerans and Pseudomonas fluorescens were analysed.

  17. A Survey of Game Theoretic Approaches to Modelling Decision-Making in Information Warfare Scenarios

    Directory of Open Access Journals (Sweden)

    Kathryn Merrick


    Full Text Available Our increasing dependence on information technologies and autonomous systems has escalated international concern for information- and cyber-security in the face of politically, socially and religiously motivated cyber-attacks. Information warfare tactics that interfere with the flow of information can challenge the survival of individuals and groups. It is increasingly important that both humans and machines can make decisions that ensure the trustworthiness of information, communication and autonomous systems. Subsequently, an important research direction is concerned with modelling decision-making processes. One approach to this involves modelling decision-making scenarios as games using game theory. This paper presents a survey of information warfare literature, with the purpose of identifying games that model different types of information warfare operations. Our contribution is a systematic identification and classification of information warfare games, as a basis for modelling decision-making by humans and machines in such scenarios. We also present a taxonomy of games that map to information warfare and cyber crime problems as a precursor to future research on decision-making in such scenarios. We identify and discuss open research questions including the role of behavioural game theory in modelling human decision making and the role of machine decision-making in information warfare scenarios.

  18. Technological, military and social causes for the application of cyber warfare

    Directory of Open Access Journals (Sweden)

    Dragan D. Mladenović


    Full Text Available Cyber warfare is a specific new form of military conflicts the use of which is growing rapidly in the international community. However, its nature is specific and differs from all previously known forms of warfare. For the purpose of clear understanding of the nature of cyber warfare, this paper covers the basic groups of preconditions for its broad application and fast development from technological, military and social aspects. Understanding the true nature of cyber warfare is a necessary condition for building national capacities for its application that are military justified and harmonized with the international law. The paper explores the characteristic instances of cyber warfare, ranging from information propaganda to physical destruction, with the goal to determine guidelines for the possible development of cyber capacities at the national level. Based on the analysis of previous cyber warfare cases, a prediction of future development directions is made and the necessity to apply suitable methods and techniques for defense against them is analyzed.

  19. Platform-level Distributed Warfare Model-based on Multi-Agent System Framework

    Directory of Open Access Journals (Sweden)

    Xiong Li


    Full Text Available The multi-agent paradigm has become a useful tool in solving military problems. However, one of key challenges in multi-agent model for distributed warfare could be how to describe the microcosmic  tactical warfare platforms actions. In this paper, a platform-level distributed warfare model based on multi-agent system framework is designed to tackle this challenge. The basic ideas include:  Establishing multi-agent model by mapping from tactical warfare system’s members, i.e., warfare platforms, to respective agents; performing task decomposition and task allocation by using task-tree decomposition method and improved contract net protocol model technique; and implementing simulation by presenting battlefield terrain environment analysis algorithm based on grid approach. The  simulation demonstration results show that our model provides a feasible and effective approach to supporting the abstraction and representation of microcosmic tactical actions for complex warfare system.Defence Science Journal, 2012, 62(1, pp.180-186, DOI:

  20. Editorial: Discovery from Lake Turkana and History of Human Warfare

    Directory of Open Access Journals (Sweden)

    Professor S. P. Singh, Ph.D.


    Full Text Available Very interesting finds have come to light of violently killed humans from Lake Turkana in the Kenyan Rift Valley around 10000 years ago. A stunning discovery of skeletons of 27 persons who are believed to have been killed at the same time and are supposed to have suffered violent wounds has been reported recently (Nature 529, 394–398, 21 January 2016. These finds belong to a period of late Pleistocene/early Holocene of the hunter-gatherer societies from Nataruk. Among the victims were men, women and children. The individuals were killed with projectiles and blunt weapons. These skeletons were found in the lagoon and were preserved very nicely. Such type of mass killing probably could never happen as a consequence of intra-group conflict. The evidence seems to be towards warfare and aggression in ancient societies. The experts ruled out the possibility of a cemetery and ceremonial burial. This discovery of 27 skeletons points to the fact that there may have been more causalities and many individuals might have escaped death at that time. According to one of the co-authors of this research Dr. R.A. Foley, the groups were elatively more densely packed populations than the hunter gatherers and had more chances of having inter-group conflicts because of sharing the resources which would have been plentiful near the lagoons and water bodies. Violence probably has been in the instinct of early humans and that the warfare among humans has a history of 10000 years or even earlier.

  1. Toxic Chemicals in the Soil Environment. Volume 2. Interactions of Some Toxic Chemicals/Chemical Warfare Agents and Soils (United States)


    cholinesterase inhibitors . At least one, armin (O-ethyl’,ethyl 0,p-nit rophenyl phosphonate), is among the moot .powerful known choliniesterase inhibitor ...and is equivalent to the nerve 4 agents (Feat and Schmidt, 1973). All have been used as growth Inhibitors or terminators for some organisms...there was inhibition of the urease and oxidase enzymes. 2.2.4 Effects of Ozone and Sunlight on Orgenophoapborua Pesticides Spencer et al. (1980

  2. Passive front-ends for wideband millimeter wave electronic warfare (United States)

    Jastram, Nathan Joseph

    This thesis presents the analysis, design and measurements of novel passive front ends of interest to millimeter wave electronic warfare systems. However, emerging threats in the millimeter waves (18 GHz and above) has led to a push for new systems capable of addressing these threats. At these frequencies, traditional techniques of design and fabrication are challenging due to small size, limited bandwidth and losses. The use of surface micromachining technology for wideband direction finding with multiple element antenna arrays for electronic support is demonstrated. A wideband tapered slot antenna is first designed and measured as an array element for the subsequent arrays. Both 18--36 GHz and 75--110 GHz amplitude only and amplitude/phase two element direction finding front ends are designed and measured. The design of arrays using Butler matrix and Rotman lens beamformers for greater than two element direction finding over W band and beyond using is also presented. The design of a dual polarized high power capable front end for electronic attack over an 18--45 GHz band is presented. To combine two polarizations into the same radiating aperture, an orthomode transducer (OMT) based upon a new double ridge waveguide cross section is developed. To provide greater flexibility in needed performance characteristics, several different turnstile junction matching sections are tested. A modular horn section is proposed to address flexible and ever changing operational requirements, and is designed for performance criteria such as constant gain, beamwidth, etc. A multi-section branch guide coupler and low loss Rotman lens based upon the proposed cross section are also developed. Prototyping methods for the herein designed millimeter wave electronic warfare front ends are investigated. Specifically, both printed circuit board (PCB) prototyping of micromachined systems and 3D printing of conventionally machined horns are presented. A 4--8 GHz two element array with

  3. Guerilla Warfare & Law Enforcement: Combating the 21st Century Terrorist Cell within the U.S.

    Directory of Open Access Journals (Sweden)

    Major Richard Hughbank


    Full Text Available Both domestic and international terrorist organizations employ guerrilla warfare tactics, techniques, and procedures. Thus, the ability to identify and defeat the members of these organizations, cripple their infrastructures, and disrupt their financial resources lies in the understanding of modern guerrilla warfare as it develops in the twenty-first century within the United States.3 The forms of asymmetric warfare4 adopted by domestic and international terrorist groups alike is no longer intended to gain simple media exposure or governmental manipulation; they want to make an overpowering impact by causing massive loss of life and severe damage to infrastructure and are often motivated by religious imperatives and political goals. As terrorism analyst Stephen Flynn has observed, "Throughout the 20th century [Americans] were able to treat national security as essentially an out-of-body experience. When confronted by threats, [America] dealt with them on the turf of our allies or our adversaries. Aside from the occasional disaster and heinous crime, civilian life [in the United States] has been virtually terror-free." With the turn of the twenty-first century, terrorist operations have become more prevalent in the United States and are taking shape in the form of modern guerrilla warfare, thus creating new challenges for federal, state, and local law enforcement agencies. After reviewing the origin and nature of these challenges, this article will offer some suggestions for countering guerilla warfare in the United States.

  4. Drone Warfare: Twenty-First Century Empire and Communications

    Directory of Open Access Journals (Sweden)

    Kevin Howley


    Full Text Available This paper, part of a larger project that examines drones from a social-construction of technology perspective, considers drone warfare in light of Harold Innis’s seminal work on empire and communication. Leveraging leading-edge aeronautics with advanced optics, data processing, and networked communication, drones represent an archetypal “space-biased” technology. Indeed, by allowing remote operators and others to monitor, select, and strike targets from half a world away, and in real-time, these weapon systems epitomize the “pernicious neglect of time” Innis sought to identify and remedy in his later writing. With Innis’s time-space dialectic as a starting point, then, the paper considers drones in light of a longstanding paradox of American culture: the impulse to collapse the geographical distance between the United States and other parts of the globe, while simultaneously magnifying the cultural difference between Americans and other peoples and societies. In the midst of the worldwide proliferation of drones, this quintessentially sublime technology embodies this (disconnect in important, profound, and ominous ways.

  5. Back to the future: aerial warfare in Libya

    Directory of Open Access Journals (Sweden)

    João Paulo Nunes Vicente


    Full Text Available A century after the first air bomb mission, a new intervention in the same geographic space has made evident the changes in Airpower. The Aerial Warfare in Libya has radically changed the civil war, complying with a UN mission to protect Libyan population, imposing a no-fly zone and an arms embargo. Therefore, Operation Unified Protector became one of the most successful campaigns in the history of NATO. We aim to assess the operational efficiency of Airpower in the conflict in Libya, focusing on the challenges of a War essentially Aerial. Despite the military results and the fact that some political objectives were met, we can identify some concerning trends that, if not shifted, may negatively influence future NATO operations. We do not aim to draw general and universal conclusions on the strategic value of Airpower based on the analysis of a specific case. Above all, we focus on identifying some lessons which have influenced OUP operational efficiency. Thus, we must analyze some factors, such as the scope of objectives, the type of opposing action and aerial strategy used by the coalition and then focus on the challenges arising from the OUP.

  6. Research on performance of ethernet interface in network centric warfare

    Institute of Scientific and Technical Information of China (English)

    梁永生; 张乃通


    The concept of network centric warfare (NCW) and its character, high requirement of real-time synchronization are introduced. The distributed equal-node network architecture in NCW is presented. Based on theoretical analysis on ethernet interface performance, this paper presents that forwarding latency between ethernet interface devices is a key influence factor of real-time synchronization in NCW. Ethernet fundamental is briefly introduced. The model between a switch under test (SUT) and a smartbits card is presented and used for two interconnecting switches in NCW. On condition that ignoring the latency of connecting fiber or twisted pairs and processing latency of the smartbits test system, this paper presents that clock frequency tolerance (CFT) between a SUT and a smartbits card is a leading influence factor of forwarding latency of an ethernet switch. The formulae to calculate internal forwarding latency and forwarding latency caused by its CFT are deduced. Theoretical calculation on forwarding latency of an ethernet switch based on the given CFT and test time is implemented. Experimental study on primary forwarding latency and secondary forwarding latency is implemented and forwarding latency between the SUT and the smartbits card is measured, thus testifying the accuracy of the above theoretical analysis that the CFT is a key influence factor of forwarding latency. The measures to satisfy the needs of forwarding latency in NCW are presented.

  7. SiGe-based re-engineering of electronic warfare subsystems

    CERN Document Server

    Lambrechts, Wynand


    This book equips readers with a thorough understanding of the applicability of new-generation silicon-germanium (SiGe) electronic subsystems for the military purposes of electronic warfare and defensive countermeasures. The theoretical and technical background is extensively explained and all aspects of the integration of SiGe as an enabling technology for maritime, land, and airborne (including space) electronic warfare are addressed, including research, design, development, and implementation. The coverage is supported by mathematical derivations, informative illustrations, practical examples, and case studies. While SiGe technology provides speed, performance, and price advantages in many markets, sharing of information on its use in electronic warfare systems has to date been limited, especially in developing nations. This book will therefore be warmly welcomed as an engineering guideline that focuses especially on the speed and reliability of current-generation SiGe circuits and highlights emerging innov...

  8. The United States and biological warfare: secrets from the early cold war and Korea. (United States)

    Bruwer, A


    The United States and Biological Warfare is about accusations that the United States resorted to bacteriological warfare at a time of great military stress during the Korean War. In December 1951, the then US Secretary of Defense ordered early readiness for offensive use of biological weapons. Soon afterwards, the North Korean and Chinese armies accused the United States of starting a large-scale biological warfare experiment in Korea. The US State Department denied the accusation. Both parties to the dispute maintain their positions today. The authors spent 20 years researching the accusations in North America, Europe and Japan. They were the first foreigners to be given access to Chinese classified documents. The reader is also introduced to the concept of 'plausible denial', an official US policy which allowed responsible governmental representatives to deny knowledge of certain events. The authors hope that their work will contribute to the understanding of a time when modern war expanded into a new type of violence.


    Directory of Open Access Journals (Sweden)

    Sorin DUCARU


    Full Text Available The technological development and the instant communication possibilities advanced not only economic and social developments, but also evolving threats from those who exploit the vulnerabilities of communication and information systems. The cyber threat landscape points to a significant increase of the frequency, intensity, duration and sophistication of cyber-attacks. One of the new and concerning trends is the use of cyber capabilities in relation with military of hybrid operations – the so-called cyber dimension of hybrid warfare. NATO’s strategy on countering hybrid warfare is based on the triad: prepare-deter-defend, which also applies to cyber. Nations represent the first line of defence in countering hybrid strategies. International cooperation is also a key factor in this sense. It is in this context that NATO’s response to cyber-attacks in the context of hybrid warfare must be further refined.

  10. Mustard Group Chemical War Agents from Preventive Medicine Perspective

    Directory of Open Access Journals (Sweden)

    Muharrem Ucar


    Full Text Available Although many preventive efforts and treaties, chemical warfare agents have still been a severe assault form against both military and civilian individuals. The most important chemical warfare agents sulphur mustard and others are easy to handle and cheap those the important reasons to accept sulphur mustard as a chemical warfare agent. Many individuals attacked by sulphur mustard have severe health problems such as respiratory system diseases. After ten years of sulphur mustard exposure, several health problems such as respiratory tract problems (%42.5, eye problems (%40 and other systemic diseases have been observed to insist on induviduals when examined. Exposure of even single sulphur mustard exposure has been seen to result high level of disability and early deaths. In spite of the fact that there is no available antidote and/or remedy against sulphur mustard exposure, our country has an incremental chemical assault threat for both military personels and civilians because of its jeopolitics position. Experimental studies regarding sulphur mustard toxicity will be helpful for novel preventive strategies and antidot devolepment. [TAF Prev Med Bull 2007; 6(3.000: 209-214

  11. Skeletal evidence for Inca warfare from the Cuzco region of Peru. (United States)

    Andrushko, Valerie A; Torres, Elva C


    This article addresses the bioarchaeological evidence for Inca warfare through an analysis of 454 adult skeletons from 11 sites in the Inca capital region of Cuzco, Peru. These 11 sites span almost 1000 years (AD 600-1532), which allows for a comparison of the evidence for warfare before the Inca came to power (Middle Horizon AD 600-1000), during the time of Inca ascendency in the Late Intermediate Period (AD 1000-1400), and after the Inca came to power and expanded throughout the Cuzco region and beyond (Inca Imperial Period, AD 1400-1532). The results indicate that 100 of 454 adults (22.0%) showed evidence of cranial trauma. Of these, 23 individuals had major cranial injuries suggestive of warfare, consisting of large, complete, and/or perimortem fractures. There was scant evidence for major injuries during the Middle Horizon (2.8%, 1/36) and Late Intermediate Period (2.5%, 5/199), suggesting that warfare was not prevalent in the Cuzco region before and during the Inca rise to power. Only in the Inca Imperial Period was there a significant rise in major injuries suggestive of warfare (7.8%, 17/219). Despite the significant increase in Inca times, the evidence for major cranial injuries was only sporadically distributed at Cuzco periphery sites and was entirely absent at Cuzco core sites. These findings suggest that while the Inca used warfare as a mechanism for expansion in the Cuzco region, it was only one part of a complex expansion strategy that included economic, political, and ideological means to gain and maintain control.

  12. Particle Swarm Social Adaptive Model for Multi-Agent Based Insurgency Warfare Simulation

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Xiaohui [ORNL; Potok, Thomas E [ORNL


    To better understand insurgent activities and asymmetric warfare, a social adaptive model for modeling multiple insurgent groups attacking multiple military and civilian targets is proposed and investigated. This report presents a pilot study using the particle swarm modeling, a widely used non-linear optimal tool to model the emergence of insurgency campaign. The objective of this research is to apply the particle swarm metaphor as a model of insurgent social adaptation for the dynamically changing environment and to provide insight and understanding of insurgency warfare. Our results show that unified leadership, strategic planning, and effective communication between insurgent groups are not the necessary requirements for insurgents to efficiently attain their objective.

  13. A Theoretical Exploration of Lawrence of Arabia’s Inner Meanings on Guerrilla Warfare (United States)


    Asprey, Robert . War in the shadows: The Guerrilla in history, ( Lincoln, NE: iUniverse, 2002), 4 2 T.E. Lawrence, The Seven Pillars of Wisdom. A...the Solow growth model and the Ricardian model of economic rent, with two classic studies of guerrilla warfare by T.E Lawrence and Mao Zedong. Four

  14. Fear as a medium of communication in asymmetric forms of warfare

    DEFF Research Database (Denmark)

    Harste, Gorm


    of fear evolves in asymmetric warfare. Asymmetric war induces fear in both parties, but in a communicative form that leads to very different experiences of fear. Fear is observed and analysed with Niklas Luhmann’s theory of self-referential systems of communication and well as his theory of risk...

  15. From Douhet to drones, air warfare, and the evolution of targeting

    NARCIS (Netherlands)

    Osinga, F.P.B.; Roorda, M.P.; Ducheine, P.A.L.; Schmitt, M.N.; Osinga, F.P.B.


    Through the prism of the experience of air warfare, this chapter identifies key factors that have shaped targeting. These include technological developments, organizational structures, and processes and inter-service competition for scarce resources. Moreover, targeting is informed by perspectives o

  16. A statistical analysis of the effect of warfare on the human secondary sex ratio

    NARCIS (Netherlands)

    Graffelman, J.; Hoekstra, R.F.


    Many factors have been hypothesized to affect the human secondary sex ratio (the annual percentage of males among all live births), among them race, parental ages, and birth order. Some authors have even proposed warfare as a factor influencing live birth sex ratios. The hypothesis that during and s

  17. Development of Novel Alternative Technologies for Decontamination of Warfare Agents: Electric Heating with Intrinsically Conductive Polymers (United States)


    in converting electric energy to thermal energy for the decon applications. Other conductive materials, such as polythiophenes , polypyrroles, carbon...Development of Novel Alternative Technologies for Decontamination of Warfare Agents: Electric Heating with Intrinsically Conductive Polymers...Joule)-heating with conducting polymers. The basic concept is that electrically conducting polymers, such as polyaniline, can be used as coatings or

  18. (Review of) Reno, William. 2011. Warfare in Independent Africa. Cambridge: Cambridge University Press

    DEFF Research Database (Denmark)

    Hagmann, Tobias


    Warfare in Independent Africa is Reno’s bold attempt to analyze the modern history of African insurgencies. The book tackles this task through the prism of five generations of rebel, which left their mark on the continent; anti-colonial rebels, majority rule rebels, reform rebels, warlord rebels ...


    Directory of Open Access Journals (Sweden)

    Nane Zeynalyan


    Full Text Available In the recent decades, war fields have moved into the information sphere. Today’s person has reason to “be informed”; as having information provides a sense of security. In the modern world, great effort is invested in expanding information sources, because it serves to articulate both international policies and the context of wars. The exchange of information in domestic and international platforms influences the quality of public debate and ideology, which affects social attitudes and decision-making processes. This article presents the role of information-psychological warfare as a factor in forming public opinion. It discusses the peculiarities of organizing an information-psychological warfare during military conflicts. The goal of our research is to explore how social groups might perceive peculiarities in the information-psychological warfare. The research involves methods of survey, content analysis, and free associations. The effectiveness of psychological warfare significantly depends on how people perceive information. Consequently, in the contemporary world, it is necessary to not only protect or fight on the battlefield, but also to use information weapons. This imposes requirements on psychological scientists to explore peculiarities around the perception of information to help find mechanisms that safeguard people’s lives by way of contributing to the formation of necessary attitudes and stereotypes.

  20. Detachment 101 in the CBI: An Unconventional Warfare Paradigm for Contemporary Special Operations (United States)


    American Espionage. NY: Reynal and Hitchcock , 1946. Barrett, Neil H. Chingpaw. NY: Vantage, 1962. Bartholomew-Feis, Dixee R. The O.S.S. and Ho Chi...United States Army. Washington, D.C.: U.S. Government Printing Office, 1990. Paddock, Alfred H. U.S. Army Special Warfare; Its Origins. Lawrence, KS

  1. Military medicine and the ethics of war: British colonial warfare during the Seven Years War (1756-63). (United States)

    Charters, Erica


    This article examines 18th-century European warfare, tracing the first formal codifications of conventions of war, frequently introduced by military physicians and initially regarding the treatment of the sick and wounded. It outlines to what extent these conventions were followed in practice, particularly in the challenging environment of American irregular warfare, with a focus on the most well-known incident of "biological warfare" in the period: the deliberate spread of smallpox by British officers among Amerindians in 1763. More broadly, it demonstrates that the history of military medicine provides a fruitful method with which to uncover assumptions about the ethics of war.

  2. A Review of Chemical Warfare Agent (CWA) Detector Technologies and Commercial-Off-The-Shelf Items (United States)


    lithium thionyl chloride batteries74 Battery , external power supply of rechargeable battery78 110 (+/-10%) VAC 50/60 Hz or 600 watts77. Operational Life...dioxide battery or 12V power supply6, 39, 40 6 standard ‘C’ alkaline batteries44 Rechargeable lithium -ion battery46 Rechargeable lithium - ion... battery pack51 Lithium manganese dioxide batteries or power supply56 Lithium -sulfur dioxide battery ,

  3. The DTIC Review: Volume 2, Number 4, Surviving Chemical and Biological Warfare (United States)


    Septem ber 1995 ............................................................................................... 9 E lectronic R eferences...will arise substantially. Correspondingly, the US, the UK, and has been exposed to dirt, sweat, cigarette smoke, engine their allies will find defense of

  4. Specialized insulin is used for chemical warfare by fish-hunting cone snails (United States)

    Safavi-Hemami, Helena; Gajewiak, Joanna; Karanth, Santhosh; Robinson, Samuel D.; Ueberheide, Beatrix; Douglass, Adam D.; Schlegel, Amnon; Imperial, Julita S.; Watkins, Maren; Bandyopadhyay, Pradip K.; Yandell, Mark; Li, Qing; Purcell, Anthony W.; Norton, Raymond S.; Ellgaard, Lars; Olivera, Baldomero M.


    More than 100 species of venomous cone snails (genus Conus) are highly effective predators of fish. The vast majority of venom components identified and functionally characterized to date are neurotoxins specifically targeted to receptors, ion channels, and transporters in the nervous system of prey, predators, or competitors. Here we describe a venom component targeting energy metabolism, a radically different mechanism. Two fish-hunting cone snails, Conus geographus and Conus tulipa, have evolved specialized insulins that are expressed as major components of their venoms. These insulins are distinctive in having much greater similarity to fish insulins than to the molluscan hormone and are unique in that posttranslational modifications characteristic of conotoxins (hydroxyproline, γ-carboxyglutamate) are present. When injected into fish, the venom insulin elicits hypoglycemic shock, a condition characterized by dangerously low blood glucose. Our evidence suggests that insulin is specifically used as a weapon for prey capture by a subset of fish-hunting cone snails that use a net strategy to capture prey. Insulin appears to be a component of the nirvana cabal, a toxin combination in these venoms that is released into the water to disorient schools of small fish, making them easier to engulf with the snail’s distended false mouth, which functions as a net. If an entire school of fish simultaneously experiences hypoglycemic shock, this should directly facilitate capture by the predatory snail. PMID:25605914

  5. Prolonged Inhibition of Motor Activity Following Repeated Exposure to Low Levels of Chemical Warfare Agent VX (United States)


    Anxious mice tend to avoid the brightly lit center of the maze, and display thigmotaxis (wall following), in which they closely walk along the...analysis of the mouse open field test: effects of diazepam , chlordiazepoxide and an extremely low frequency pulsed magnetic field, Neurosci Biobehav

  6. Chemical Warfare Agent Operational Exposure Hazard Assessment Research: FY07 Report and Analysis (United States)


    accidentally exposed to VX vapor. The method employs GC-MS/MS on a triple quadrupole mass spectrometer using stable isotope dilution for quantitation... Technique for Assessing Exposure to VX via GC-MS/MS Analysis 85 3.3.1 Introduction 85 3.3.2 Materials and Methods 85 3.3.3 Results and Discussion 90...guinea pigs were anesthetized using isoflurane (3% induction, 15-2% maintenance; with oxygen). All procedures were performed using aseptic technique

  7. Chemical Warfare Agent Surface Adsorption: Hydrogen Bonding of Sarin and Soman to Amorphous Silica (United States)


    small transfer chamber located within the confines of a CWA-certified surety fume hood . Within the main chamber, the sample was mounted on a molybdenum...Particulate silica surface samples were prepared by dispersing silica (200 m2/g, Aerosil fumed silica with a 12 nm average particle diameter) from a

  8. Improving Blood Monitoring of Enzymes as Biomarkers of Risk from Anticholinergic Pesticides and Chemical Warfare Agents (United States)


    One approach would be to use the colorimetric two substrate ( diazinon -oxon and paraoxon) PON1 assay (Richter, et al., 2004, Costa, et al., 2005a...and, its limited usefulness as a test of liver function. J Lab Clin Med 40:692–702. Harris, E.K. (1974). Effects of intra- and interindividual varia...Vorhaus, L.J., II, Scudamore, H.H., Kark, R.M. (1950). Measurement of serum cholinesterase activty in the study of disease of the liver and biliary

  9. Biodegradation of an Organophosphate Chemical Warfare Agent Simulant by Activated Sludge with Varying Solid Retention Times (United States)


    0.72 g Na3NTA * 2H2O , 0.3 g Na3EDTA * 4H2O, 3.0 g FeCl3 * 6H2O, 0.5 g H3BO3, 0.3 g ZnSO4 * 7H2O, 0.24 g MnCl2 * 4H2O, 0.14 g CuSO4 * 5H2O, 0.06 g KI...through reactions shown in equations 2-4. 12 NH3 + O2 + 2e - +2H + - -> NH2OH + H2O (2) NH2OH + H2O + 1/2 O2--> NO 2- + 2H2O + H + (3...1.25 g NaCH3COO, 2.26 g NH4Cl, 6.86 g MgCl2 * 6H2O, 1.72 g CaCl2 * 2H2O , 0.6675 g KH2PO4 and 20 mL of a trace element solution adapted from

  10. Decontamination of chemical warfare sulfur mustard agent simulant by ZnO nanoparticles (United States)

    Sadeghi, Meysam; Yekta, Sina; Ghaedi, Hamed


    In this study, zinc oxide nanoparticles (ZnO NPs) have been surveyed to decontaminate the chloroethyl phenyl sulfide as a sulfur mustard agent simulant. Prior to the reaction, ZnO NPs were successfully prepared through sol-gel method in the absence and presence of polyvinyl alcohol (PVA). PVA was utilized as a capping agent to control the agglomeration of the nanoparticles. The formation, morphology, elemental component, and crystalline size of nanoscale ZnO were certified and characterized by SEM/EDX, XRD, and FT-IR techniques. The decontamination (adsorption and destruction) was tracked by the GC-FID analysis, in which the effects of polarity of the media, such as isopropanol, acetone and n-hexane, reaction time intervals from 1 up to 18 h, and different temperatures, including 25, 35, 45, and 55 °C, on the catalytic/decontaminative capability of the surface of ZnO NPs/PVA were investigated and discussed, respectively. Results demonstrated that maximum decontamination (100 %) occurred in n-hexane solvent at 55 °C after 1 h. On the other hand, the obtained results for the acetone and isopropanol solvents were lower than expected. GC-MS chromatograms confirmed the formation of hydroxyl ethyl phenyl sulfide and phenyl vinyl sulfide as the destruction reaction products. Furthermore, these chromatograms proved the role of hydrolysis and elimination mechanisms on the catalyst considering its surface Bronsted and Lewis acid sites. A non-polar solvent aids material transfer to the reactive surface acid sites without blocking these sites.

  11. The Rollback of South Africa’s Chemical and Biological Warfare Program (United States)


    ricin and botulinum. Reportedly, they had acquired anthrax, Plague, cholera, E. coli, staph, necrotizing fasciitis , ricin, botulinum, gas gangrene, anti...before been seen. Project Coast managed to obtain the Soviet-developed flesh-eating bacteria, necrotizing fasciitis , as well as the antidote. In

  12. Diagnosis of Exposure to Chemical Warfare Agents: A Comprehensive Literature Survey 1990-2005 (United States)


    30S,02S," O2S, CH2 CH 2SCH3 CH 2CH2 SOCH 3 CH2 CH 2SCH 3 (2) (3) (10) Single stage GC-MS analysis, using positive ammonia CI and SIM of [M+NH 4]+, m...methodology, N7-HETE- Gua was detected in the spleen and liver of rats exposed percutaneously to sulfur mustard (Rao et al., 2002). b) Other physicochemical

  13. Methods of Advanced Wound Management for Care of Combined Traumatic and Chemical Warfare Injuries (United States)


    213–7. 30. Peponis V, Rosenberg P, Reddy SV, Herz JB, Kaufman HE. The use of the Fugo Blade in corneal surgery: a preliminary animal study. Cornea ...treatment of diabetic foot ulceration . Br J Nurs. 2006;15(15):S12–7. 40. Stetter C, Plaza T, von den Driesch P. Skin grafting of a chronic leg ulcer with...debridement of hard to heal leg ulcers by means of a new device based on Fluidjet technology. Int Wound J. 2005;2(4):307–14. 43. Rennekampff HO

  14. Oxidative degradation of chemical warfare agents in water by bleaching powder. (United States)

    Qi, Lihong; Zuo, Guomin; Cheng, Zhenxing; Zhu, Haiyan; Li, Shanmao


    Degradation of sulfur mustard (HD), S-2-(di-isopropylamino)ethyl O-ethyl methylphosphonothioate (VX) and Soman (GD) in water by bleaching powder was investigated. The degradation products were comprehensively analyzed by gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS) and ion chromatography. Degradation pathways were deduced based on the identified products. The product analysis results indicated that HD could be degraded through oxidation and chlorination reactions, and a small portion of sulfur atoms could be mineralized into SO(4)(2-) ion. Oxidative degradation of VX could finally generate O-ethyl methylphosphonate acid (EMPA), sulfonic acids, SO(4)(2-) and NO(3)(-) ions. GD would be converted into non-toxic pinacolyl methylphosphonate via nucleophilic substitution.

  15. Five-Year Follow-Up of Army Personnel Potentially Exposed to Chemical Warfare Agents (United States)


    21.3 0.93 (0.83-1.04) Neuralgia or neuritis 6.8 6.4 1.05 (0.85-1.30) Any disease of genital organs 6.3 6.6 0.94 (0.76-1.17) Heart disease 1.8 1.8 0.98...Recurrent headaches 46.8 42.0 0.20 Ž:7 14.1 12.8 Migraines 19.0 20.3 0.66 Not answered - - 0.45 Neuralgia or neuritis 6.2 7.5 0.50 Hospitalizations...other cancer, tunity to look at the possible effects of notification on health. The recurrent headache, and neuralgia . Only recurrent headache fact that

  16. Transport and Reactivity of Decontaminants to Provide Hazard Mitigation of Chemical Warfare Agents from Materials (United States)


    Liquids through Polymer Membranes .5. Neoprene, Styrene Butadiene Rubber , Ethylene Propylene Diene Terpolymer, and Natural - Rubber Versus Hydrocarbons...Membranes .2. Neoprene, SBR, EPDM, NBR, and Natural - Rubber Versus Normal-Alkanes. J. Appl. Polym. Sci. 1991, 42 (8), 2329–2336. 24. Harogoppad, S.B...highly absorptive (e.g., tire rubber ). Absorptive materials are often more challenging to decontaminate because of the reduced accessibility of the

  17. In Situ Studies of the Decomposition of Simulated Chemical Warfare Agents on Nanoparticle Catalysts (United States)


    insufficient energy for interdiffusion of Rh into bulk Pt surfaces.9,24,25 In addition, Monte Carlo simulations of a 1000-atom Au(50%)-Pt(50...12949. (22) Hernandez-Fernandez, P.; Rojas, S.; Ocon, P.; de la Fuente , J. L. G.; Fabian, J. S.; Sanza, J.; Pena, M. A.; Garcia-Garcia, F. J

  18. Chiral Separation of G-type Chemical Warfare Nerve Agents via Analytical Seupercritical Fluid Chromatography (United States)


    by HPLC have not been well characterized . Supercritical fluid chromatography (SFC) is a well- established chiral chromatography technology that offers...smoothed chromatograms. For presentation purposes only smoothed chromatograms are shown. Chromatographic Characterization Chromatography parameters were...under these conditions (data not shown). Various other polysaccharide -type chiral columns (Chiralpak AD-H, Chiralcel OJ-RH, Chiralpak IB) were tested

  19. Methyl Salicylate: A Reactive Chemical Warfare Agent Surrogate to Detect Reaction with Hypochlorite (POSTPRINT) (United States)


    acid (Fisher Scientific, Fair Lawn, NJ) was diluted to 1.0 M in water purified by reverse osmosis . Methods. Reactions were initially examined by...reactivity of hypochlorite neutralizants delivered onto a substrate is strongly diffusion limited, an observation likely to be useful as a

  20. Ram-air sample collection device for a chemical warfare agent sensor (United States)

    Megerle, Clifford A.; Adkins, Douglas R.; Frye-Mason, Gregory C.


    In a surface acoustic wave sensor mounted within a body, the sensor having a surface acoustic wave array detector and a micro-fabricated sample preconcentrator exposed on a surface of the body, an apparatus for collecting air for the sensor, comprising a housing operatively arranged to mount atop the body, the housing including a multi-stage channel having an inlet and an outlet, the channel having a first stage having a first height and width proximate the inlet, a second stage having a second lower height and width proximate the micro-fabricated sample preconcentrator, a third stage having a still lower third height and width proximate the surface acoustic wave array detector, and a fourth stage having a fourth height and width proximate the outlet, where the fourth height and width are substantially the same as the first height and width.

  1. A Survey and Evaluation of Chemical Warfare Agent-Decontaminants and Decontamination (United States)


    APD) is also an all purpose decontaminant. It consists of 551 (V/V) of monoethanol - amine , 45% (V/V) of 2-hydroxyl-l-propylamine, 25% (Wt/V) of lithium...been conducted. Sawdust, soil, silicone, coal dust, amine or sulfonic acid-containing polymers, organic and inorganic ion-exchange materials, and metal...It is a relatively corrosive superbase which consists of 701 diethylenetri- amine , 28% 2-methoxy ethanol, and 2% sodium hydroxide. The half lives

  2. Biosensor-Based Detection and Verification System for Bio-Chemical Warfare Agents (United States)


    23 The second alternative detection scheme is gated integration (GI). In GI, the photocurrent from the LAPS is collected on a feedback capacitor ...magnitude of the internal photovoltage can be estimated by dividing the charge output form the LAPS by the magnitude of the insulator capacitor . For the case...uI184eiG)u3 C fousJiojdosi Ioqoeqie3 0. loqia)e 00 Lf ; CJ CS (9s~e~jou */) asuodseU (Silicone) (.002’ Polyester )I I Ir ScreenI (PeCap 7-88/34)I I (.012 "x

  3. Marital Relationship and Its Associated Factors in Veterans Exposed to High Dose Chemical Warfare Agents

    Directory of Open Access Journals (Sweden)

    Shervin Assari


    Full Text Available Objective: The aim of this study was to determine the associates of marital relationship in mustard exposed veterans.Materials and Methods: Two hundred ninety two married Iranian mustard exposed veterans, who had been exposed to single high dose mustard gas in Iraq-Iran war, were assessed for marital adjustment with Revised Dyadic Adjustment Scale (RDAS. Census sampling was done. The patients' quality of life (SF-36, spirometric measures and war related data were also extracted.Results: A total of 189 subjects (65% completed our study. The mean (±SD of the RDAS Total score, RDAS Dyadic Consensus , RDAS Affectional Expression, RDAS Dyadic Satisfaction , and RDAS Dyadic Cohesion were 50.61 (8.16, 16.67 (2.77, 7.62 (1.84, 14.76 (3.39, and 11.54 (3.79, respectively. RDAS Dyadic satisfaction was correlated with SF-36 and all its sub-scores (p<0.05. RDAS total score showed significant correlation with SF-36 total score and most of its sub-scores (p<0.05. RDAS affective expression was significantly correlated with role limitation, social function, general mental health, vitality, General health perceptions, physical composite score (PCS and mental composite score (MCS (p<0.05. RDAS dyadic consensus was not correlated with any SF-36 sub-scores.Conclusion: Veterans health team including physicians, psychologists and/or psychiatrists should know that poorer marital satisfaction is linked with lower quality of life scores, late after mustard exposure, although marital relationship is independent of spirometric findings, age, duration from exposure and comorbidity score.

  4. Study of Sleeping in a Chemical Protective Ensemble in a Warfare Environment (United States)


    levels was the same for all experiments. This sched- ule is given in Table 4. A tape-recorded soundtrack normally used for vigilance testing ( tested at bedtime and upon awakening, using an acceptable method other than CO2 monitoring. g. Videotape or movie films could serve as a useful

  5. Enzymatic neutralization of the chemical warfare agent VX: evolution of phosphotriesterase for phosphorothiolate hydrolysis. (United States)

    Bigley, Andrew N; Xu, Chengfu; Henderson, Terry J; Harvey, Steven P; Raushel, Frank M


    The V-type nerve agents (VX and VR) are among the most toxic substances known. The high toxicity and environmental persistence of VX make the development of novel decontamination methods particularly important. The enzyme phosphotriesterase (PTE) is capable of hydrolyzing VX but with an enzymatic efficiency more than 5 orders of magnitude lower than with its best substrate, paraoxon. PTE has previously proven amenable to directed evolution for the improvement of catalytic activity against selected compounds through the manipulation of active-site residues. Here, a series of sequential two-site mutational libraries encompassing 12 active-site residues of PTE was created. The libraries were screened for catalytic activity against a new VX analogue, DEVX, which contains the same thiolate leaving group of VX coupled to a diethoxyphosphate core rather than the ethoxymethylphosphonate core of VX. The evolved catalytic activity with DEVX was enhanced 26-fold relative to wild-type PTE. Further improvements were facilitated by targeted error-prone PCR mutagenesis of loop-7, and additional PTE variants were identified with up to a 78-fold increase in the rate of DEVX hydrolysis. The best mutant hydrolyzed the racemic nerve agent VX with a value of kcat/Km = 7 × 10(4) M(-1) s(-1), a 230-fold improvement relative to wild-type PTE. The highest turnover number achieved by the mutants created for this investigation was 137 s(-1), an enhancement of 152-fold relative to wild-type PTE. The stereoselectivity for the hydrolysis of the two enantiomers of VX was relatively low. These engineered mutants of PTE are the best catalysts ever reported for the hydrolysis of nerve agent VX.

  6. Enzymatic Neutralization of the Chemical Warfare Agent VX: Evolution of Phosphotriesterase for Phosphorothiolate Hydrolysis


    Bigley, Andrew N.; Xu, Chengfu; Henderson, Terry J.; Steven P. Harvey; Raushel, Frank M.


    The V-type nerve agents (VX and VR) are among the most toxic substances known. The high toxicity and environmental persistence of VX makes the development of novel decontamination methods particularly important. The enzyme phosphotriesterase (PTE) is capable of hydrolyzing VX but with an enzymatic efficiency more than 5-orders of magnitude lower than with its best substrate, paraoxon. PTE has previously proven amenable to directed evolution for the improvement of catalytic activity against se...

  7. 78 FR 74218 - Imposition of Additional Sanctions on Syria Under the Chemical and Biological Weapons Control and... (United States)


    ... Imposition of Additional Sanctions on Syria Under the Chemical and Biological Weapons Control and Warfare.... ACTION: Notice. SUMMARY: On August 2, 2013, a determination was made that the Government of Syria used... Notice 8460. That determination resulted in sanctions against the Government of Syria. Section 307(b)...

  8. Permeation Testing of Materials With Chemical Agents or Simulants (Swatch Testing) (United States)


    chemical warfare agent (CWA) and simulant challenges through swatches of materials. Such agents include the blister agent, distilled mustard (HD) and the...2) general and specialized chemical analysis, (3) emergency response provisions, and (4) hazardous waste storage and disposal. Swatch test...moni- tor. The effluent from the vapor generator will be routed to the waste air until the challenge con- centration for the trial has stabilized

  9. Irregular Warfare and Future War: Strategy and Defense Planning; Strategic Insights, v. 10, Special issue (October 2011), 92-98. Topic: Global Trends and Future Warfare ; Part II: Technological and Doctrinal Innovation


    Russell, James A.


    This article appeared in Strategic Insights, v.10, Special issue (October 2011), 92-98. Topic: Global Trends and Future Warfare ; Part II: Technological and Doctrinal Innovation Approved for public display, distribution unlimited The purpose of this paper is threefold: to speculate on the role and prominence of irregular warfare in the strategic environment over the next quarter century, to comment on the impact that phenomenon may have on shaping the postulated scenarios addressed in t...

  10. Transport behavior of surrogate biological warfare agents in a simulated landfill: Effect of leachate recirculation and water infiltration

    KAUST Repository

    Saikaly, Pascal


    An understanding of the transport behavior of biological warfare (BW) agents in landfills is required to evaluate the suitability of landfills for the disposal of building decontamination residue (BDR) following a bioterrorist attack on a building. Surrogate BW agents, Bacillus atrophaeus spores and Serratia marcescens, were spiked into simulated landfill reactors that were filled with synthetic building debris (SBD) and operated for 4 months with leachate recirculation or water infiltration. Quantitative polymerase chain reaction (Q-PCR) was used to monitor surrogate transport. In the leachate recirculation reactors, <10% of spiked surrogates were eluted in leachate over 4 months. In contrast, 45% and 31% of spiked S. marcescens and B. atrophaeus spores were eluted in leachate in the water infiltration reactors. At the termination of the experiment, the number of retained cells and spores in SBD was measured over the depth of the reactor. Less than 3% of the total spiked S. marcescens cells and no B. atrophaeus spores were detected in SBD. These results suggest that significant fractions of the spiked surrogates were strongly attached to SBD. © 2010 American Chemical Society.

  11. An Inverse Analysis Approach to the Characterization of Chemical Transport in Paints (United States)

    Willis, Matthew P.; Stevenson, Shawn M.; Pearl, Thomas P.; Mantooth, Brent A.


    The ability to directly characterize chemical transport and interactions that occur within a material (i.e., subsurface dynamics) is a vital component in understanding contaminant mass transport and the ability to decontaminate materials. If a material is contaminated, over time, the transport of highly toxic chemicals (such as chemical warfare agent species) out of the material can result in vapor exposure or transfer to the skin, which can result in percutaneous exposure to personnel who interact with the material. Due to the high toxicity of chemical warfare agents, the release of trace chemical quantities is of significant concern. Mapping subsurface concentration distribution and transport characteristics of absorbed agents enables exposure hazards to be assessed in untested conditions. Furthermore, these tools can be used to characterize subsurface reaction dynamics to ultimately design improved decontaminants or decontamination procedures. To achieve this goal, an inverse analysis mass transport modeling approach was developed that utilizes time-resolved mass spectroscopy measurements of vapor emission from contaminated paint coatings as the input parameter for calculation of subsurface concentration profiles. Details are provided on sample preparation, including contaminant and material handling, the application of mass spectrometry for the measurement of emitted contaminant vapor, and the implementation of inverse analysis using a physics-based diffusion model to determine transport properties of live chemical warfare agents including distilled mustard (HD) and the nerve agent VX. PMID:25226346

  12. Autonomous-agent based simulation of anti-submarine warfare operations with the goal of protecting a high value unit


    Akbori, Fahrettin


    Approved for public release, distribution unlimited The Anti-Submarine Warfare screen design simulation is a program that provides a model for operations in anti-submarine warfare (ASW). The purpose of the program is to aid ASW commanders, allowing them to configure an ASW screen, including the sonar policy, convoy speed, and the number of ships, to gain insight into how these and other factors beyond their control, such as water conditions, impact ASW effectiveness. It is also designed to...

  13. Effectiveness of Unmanned Surface Vehicles in Anti-submarine Warfare with the Goal of Protecting a High Value Unit (United States)


    Surface Warfare  Special Operations Forces Support  Electronic Warfare  Maritime Interdiction Operations Support According to open online sources...Postgraduate School. These studies include maritime protection of critical infrastructure assets [30], counter- piracy escort operations in the Gulf of... Online ]. Available: [2] M. M. Graham, “Unmanned surface vehicles: An operational commander’s tool

  14. Psychological casualties resulting from chemical and biological weapons. (United States)

    Romano, J A; King, J M


    This symposium addresses the complications encountered by medical planners when confronted by the use or threat of the use of weapons of mass destruction. The types of chemical warfare agents (CWA), their principal target organs, and physiological effects are discussed. We have reviewed the use of CWA in 20th century warfare and otherwise with emphasis on five cases: (1) use of sulfur mustard during World War I; (2) use by Italy against Ethiopia; (3) use in the Sino-Japanese War; (4) relatively well-studied use in the Iran-Iraq conflict; and (5) the use of sarin in the Tokyo subway terrorist incident. We reviewed the additional physiological and psychological consequences of their use and threat of use. Results from training and simulation are discussed. Finally, we present our conclusions derived from the analysis of these historical situations.

  15. Molecules for Fluorescence Detection of Specific Chemicals (United States)

    Fedor, Steve


    A family of fluorescent dye molecules has been developed for use in on-off fluorescence detection of specific chemicals. By themselves, these molecules do not fluoresce. However, when exposed to certain chemical analytes in liquid or vapor forms, they do fluoresce (see figure). These compounds are amenable to fixation on or in a variety of substrates for use in fluorescence-based detection devices: they can be chemically modified to anchor them to porous or non-porous solid supports or can be incorporated into polymer films. Potential applications for these compounds include detection of chemical warfare agents, sensing of acidity or alkalinity, and fluorescent tagging of proteins in pharmaceutical research and development. These molecules could also be exploited for use as two-photon materials for photodynamic therapy in the treatment of certain cancers and other diseases. A molecule in this family consists of a fluorescent core (such as an anthracene or pyrene) attached to two end groups that, when the dye is excited by absorption of light, transfer an electron to the core, thereby quenching the fluorescence. The end groups can be engineered so that they react chemically with certain analytes. Upon reaction, electrons on the end groups are no longer available for transfer to the core and, consequently, the fluorescence from the core is no longer quenched. The chemoselectivity of these molecules can be changed by changing the end groups. For example, aniline end groups afford a capability for sensing acids or acid halides (including those contained in chemical warfare agents). Pyridine or bipyridyl end groups would enable sensing of metal ions. Other chemicals that can be selectively detected through suitable choice of end groups include glucose and proteins. Moreover, the fluorescent cores can be changed to alter light-absorption and -emission characteristics: anthracene cores fluoresce at wavelengths around 500 nm, whereas perylene cores absorb and emit at

  16. The Military-Entertainment Complex: A New Facet of Information Warfare

    Directory of Open Access Journals (Sweden)

    Adam Muir


    Full Text Available The second Gulf War will become synonymous with the emergence of fully-fledged information warfare where the military-entertainment complex has so influenced strategic and logistic possibilities that it becomes apparent that the war was waged as entertainment. This is entertainment not as an amusement or diversion but utilising the techniques and tropes of the burgeoning entertainment industry as a means to achieve military objectives. This paper offers a short history of the military-entertainment complex as reality and simulation become fused in the practices of the US military machine. The paper then briefly explores three central aspects of this phenomenon evident in recent developments: the military function of computer games; the role of the Hollywood scenario and the blurring between news and reality TV. Finally the suggestion is made that subverting, co-opting and reconstructing the military-entertainment complex provides new possibilities for alternative strategies of information warfare.

  17. Aerospace Power in Urban Warfare: Beware the Hornet’s Nest (United States)


    Board Task Force on Military Operations in Built-Up Areas ( MOBA )," (Washington, DC: Office of the Undersecretary of Defense for Acquisition and...Smithsonian Institute Press, 1999), 130. 45 Vick, et al., 120. 46 Rebecca A. Grant, "The Radar Game ," Air Force Magazine, February 1999, 52-60. Grant...University Press, 1962. Grant, Rebecca A. "The Radar Game ." Air Force Magazine, February 1999, 52-60. Hawkins, William R. Putting Urban Warfare in

  18. Transition Support of Meteorology and Oceanography (METOC) Technology to the Naval Oceanographic Office Warfare Support Center (United States)


    The long-term goal of this research is to support the transition of METOC technology to the Naval Oceanographic Office Warfare Support Center...Specifically, this includes the methodology for assimilation and adaptive sampling of in-situ data, collected from gliders (oceanographic) and mobile ...and acoustic uncertainty provinces, iii) continue development of the OMAS (OASIS Mobile Acoustic Source) insitu acoustic system with application to a

  19. Let the Revolution Begin, 140 Characters at a Time: Social Media and Unconventional Warfare (United States)


    2008 and Air Command and Staff College (M.A. in Military Operational Art and Science) in 2013. iv ACKNOWLEDGEMENTS I want to thank Dr. James...Sunni and Shia Muslims in the region. Arguably, social-media enabled revolutions affected Egypt the most. Overthrown twice since the January 25...Understand Unconventional Warfare,” Small Wars, 23 October 2014, art /do-we-really-understand

  20. A Need for Systems Architecture Approach for Next Generation Mine Warfare Capability (United States)


    uncontrolled mining ultimately led to the first Hague convention where 10 Henry Petroski (1992). To Engineer is...Littoral and Mine Warfare, without which I would not have been able to participate in this program. Jon, Henry and Capt. “J” juggling between work, home...Palmer, M. (1992). Guardians of the Gulf. [Photograph], Free Press, New York. Petroski , H (1992). To Engineer is Human: The Role of Failure in

  1. Navy Irregular Warfare and Counterterrorism Operations: Background and Issues for Congress (United States)


    phrase confronting irregular challenges (CIC) instead of the term irregular warfare. For purposes of convenience , this report continues to use the term...Tomahawk cruise missile attacks on suspected terrorist training camps and facilities , such as those reportedly conducted in Somalia on March 3 and May 1...domestic and overseas Navy bases and facilities ;  working with the Coast Guard to build maritime domain awareness (or MDA, meaning a real-time

  2. Guerrilla Operations in the Civil War: Assessing Compound Warfare During Price’s Raid (United States)


    hand, Three Years with Quantrill by O. S. Barton and Noted Guerrillas, or the Warfare on the Border by John Edwards provide alternate views described in other sources. For example, Barton relates John McCorkle’s account of the story about guerrillas who Price’s army before the Battle of...Jay Monaghan provided excellent accounts of the major operations in the Trans-Mississippi Department during the Civil War. Finally, the framework for

  3. China’s Development of Asymmetric Warfare and the Security of Taiwan, Republic of China (United States)


    thanks to my loving and devoted wife, Anita . Her patience, understanding, and remarkable ability to maintain a pleasant, comforting home during this...should arise (Bolt, Brenner , 2004, p.130). Information warfare technology can delay a United States response and commitment in the Taiwan Strait in...destruction of C4 systems by missiles, airpower, and high-energy weapons (Bolt & Brenner , 2004, p.133). Perhaps the most astonishing view of the PRC’s IW

  4. Courses of Action for Enhancing USAF ’Irregular Warfare’ Capabilities: A Functional Solutions Analysis (United States)


    Warfare Center to ensure that technological opportunities for novel IW appli- cations were explored, developed, and fielded. (See pp. 38–40...activities; transnational criminal activities, including narco -trafficking, illicit arms dealing, and illegal financial transactions, that support or...opportunities for novel IW applications are explored, devel- oped, and fielded. In fact, over time, it might be appropriate for the USAF to create a

  5. Challenges in Coalition Unconventional Warfare: The Allied Campaign in Yugoslavia, 1941-1945 (United States)


    JFQ 75, 4th Quarter 2014 Duke, Phil lips, and Conover 129 Challenges in Coalition Unconventional Warfare The Allied Campaign in Yugoslavia , 1941...resistance elements in Yugoslavia . The resistance movement effectively fixed in place 35 German and Italian divisions, consisting of roughly 660,000...mountain headquarters in Yugoslavia on May 14, 1944 (Imperial War Museum) Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting

  6. Cyberspace as a Complex Adaptive System and the Policy and Operational Implications for Cyber Warfare (United States)


    accessed 13 February 2014). 66Teresa Degenhard “Between War and Crime: The Overlap between War and Crime: Unpacking Foucault and Agamben’s Studies...Article-2-Revision- for- Foucault -and-Agamben-Degenhardt-July-2013.pdf (accessed 5 April 2014). 26... Foucault and Agamben’s Studies within the Context of the War on Terror.”, 34. 68US Department of Defense, Electronic Warfare, Joint Publication 3-13, I-2

  7. Molecular modeling toward selective inhibitors of dihydrofolate reductase from the biological warfare agent Bacillus anthracis. (United States)

    Giacoppo, Juliana O S; Mancini, Daiana T; Guimarães, Ana P; Gonçalves, Arlan S; da Cunha, Elaine F F; França, Tanos C C; Ramalho, Teodorico C


    In the present work, we applied docking and molecular dynamics techniques to study 11 compounds inside the enzymes dihydrofolate reductase (DHFR) from the biological warfare agent Bacillus anthracis (BaDHFR) and Homo sapiens sapiens (HssDHFR). Six of these compounds were selected for a study with the mutant BaF96IDHFR. Our results corroborated with experimental data and allowed the proposition of a new molecule with potential activity and better selectivity for BaDHFR.

  8. Management of DoD Irregular Warfare (IW) and Security Force Assistance (SFA) Capabilities (United States)


    manage DoD personnel with skills , training, education, and experience related to IW and SFA. DoDI 3000.11, May 3, 2016 TABLE OF CONTENTS 2...DOD INSTRUCTION 3000.11 MANAGEMENT OF DOD IRREGULAR WARFARE (IW) AND SECURITY FORCE ASSISTANCE (SFA) CAPABILITIES Originating Component...well as building the security capacity and capability of U.S. partners and allies. c. IW and SFA skills , training, education, and experience must be

  9. The Alpini Effect: Why the US Army Should Train Units for Mountain Warfare (United States)


    a contingent of elephants from the Spanish Ebro river over the Pyrenees , across Gaul (present day France) to the Rhone River and over the Alps into...power from disease and cold during its march over the Pyrenees and Alps.13 Switzerland quickly became a conflict zone in the early Middle Ages as... government made concessions to Prussia to resolve the conflict. Engels discussion on mountain warfare was influenced by the French Army’s success during

  10. No Compromise: Establishing Balance in the US Army’s Approach to Full-Spectrum Warfare (United States)


    also needlessly prolongs corporate acceptance for a leadership culture that appreciates the ’ fluid character of warfare in the modern era. Beyond the...of Iraq, reveals that a numl?er of tactical leaders exhibited superb situational awareness and thoughtful response to extremely dynamic security...Paul D. Batchelor , Fixing Intel: · . A B lneprint for Making Intelligence Relevant in Afghanistan, Center for a New American Security, Washington

  11. [Glanders--a potential disease for biological warfare in humans and animals]. (United States)

    Lehavi, Ofer; Aizenstien, Orna; Katz, Lior H; Hourvitz, Ariel


    Infection with Burkholderia mallei (formerly Pseudomonas mallei) can cause a subcutaneous infection known as "farcy" or can disseminate to condition known as Glanders. It is primarily a disease affecting horses, donkeys and mules. In humans, Glanders can produce four types of disease: localized form, pulmonary form, septicemia, and chronic form. Necrosis of the tracheobronchial tree and pustular skin lesions characterize acute infection with B. mallei. Other symptoms include febrile pneumonia, if the organism was inhaled, or signs of sepsis and multiple abscesses, if the skin was the port of entry. Glanders is endemic in Africa, Asia, the Middle East, and Central and South America. Glanders has low contiguous potential, but because of the efficacy of aerosolized dissemination and the lethal nature of the disease, B. mallei was considered a candidate for biological warfare. During World War I, Glanders was believed to have been spread to infect large numbers of Russian horses and mules on the Eastern front. The Japanese infected horses, civilians and prisoners of war during World War II. The USA and the Soviet Union have shown interest in B. mallei in their biological warfare program. The treatment is empiric and includes mono or poly-therapy with Ceftazidime, Sulfadiazine, Trimethoprim + Sulfamethoxazol, Gentamicin, Imipenem etc. Aggressive control measures essentially eliminated Glanders from the west. However, with the resurgent concern about biological warfare, B. mallei is now being studied in a few laboratories worldwide. This review provides an overview of the disease and presents the only case reported in the western world since 1949.

  12. Operational advantages of using Cyber Electronic Warfare (CEW) in the battlefield (United States)

    Yasar, Nurgul; Yasar, Fatih M.; Topcu, Yucel


    While cyberspace is emerging as a new battlefield, conventional Electronic Warfare (EW) methods and applications are likely to change. Cyber Electronic Warfare (CEW) concept which merges cyberspace capabilities with traditional EW methods, is a new and enhanced form of the electronic attack. In this study, cyberspace domain of the battlefield is emphazised and the feasibility of integrating Cyber Warfare (CW) concept into EW measures is researched. The SWOT (Strengths, Weaknesses, Opportunities and Threats) analysis method is used to state the operational advantages of using CEW concept in the battlefield. The operational advantages of CEW are assessed by means of its effects on adversary air defense systems, communication networks and information systems. Outstanding technological and operational difficulties are pointed out as well. As a result, a comparison of CEW concept and conventional EW applications is presented. It is concluded that, utilization of CEW concept is feasible at the battlefield and it may yield important operational advantages. Even though the computers of developed military systems are less complex than normal computers, they are not subjected to cyber threats since they are closed systems. This concept intends to show that these closed systems are also open to the cyber threats. As a result of the SWOT analysis, CEW concept provides Air Forces to be used in cyber operations effectively. On the other hand, since its Collateral Damage Criteria (CDC) is low, the usage of cyber electronic attack systems seems to grow up.

  13. Optimization of Graphene Sensors to Detect Biological Warfare Agents (United States)


    when treated with antibiotics. Untreated, it has a mortality rate between 80% and 100%. The 1979 Sverdlovsk Incident in Russia resulted in...Insights Into How Terrorists Develop Biological and Chemical Weapons,” Washington D.C., 2011. [5] N. C. F. Biotechnology Information, “Bacillus

  14. Overall view of chemical and biochemical weapons. (United States)

    Pitschmann, Vladimír


    This article describes a brief history of chemical warfare, which culminated in the signing of the Chemical Weapons Convention. It describes the current level of chemical weapons and the risk of using them. Furthermore, some traditional technology for the development of chemical weapons, such as increasing toxicity, methods of overcoming chemical protection, research on natural toxins or the introduction of binary technology, has been described. In accordance with many parameters, chemical weapons based on traditional technologies have achieved the limit of their development. There is, however, a big potential of their further development based on the most recent knowledge of modern scientific and technical disciplines, particularly at the boundary of chemistry and biology. The risk is even higher due to the fact that already, today, there is a general acceptance of the development of non-lethal chemical weapons at a technologically higher level. In the future, the chemical arsenal will be based on the accumulation of important information from the fields of chemical, biological and toxin weapons. Data banks obtained in this way will be hardly accessible and the risk of their materialization will persist.

  15. Overall View of Chemical and Biochemical Weapons

    Directory of Open Access Journals (Sweden)

    Vladimír Pitschmann


    Full Text Available This article describes a brief history of chemical warfare, which culminated in the signing of the Chemical Weapons Convention. It describes the current level of chemical weapons and the risk of using them. Furthermore, some traditional technology for the development of chemical weapons, such as increasing toxicity, methods of overcoming chemical protection, research on natural toxins or the introduction of binary technology, has been described. In accordance with many parameters, chemical weapons based on traditional technologies have achieved the limit of their development. There is, however, a big potential of their further development based on the most recent knowledge of modern scientific and technical disciplines, particularly at the boundary of chemistry and biology. The risk is even higher due to the fact that already, today, there is a general acceptance of the development of non-lethal chemical weapons at a technologically higher level. In the future, the chemical arsenal will be based on the accumulation of important information from the fields of chemical, biological and toxin weapons. Data banks obtained in this way will be hardly accessible and the risk of their materialization will persist.

  16. Venezuela as an Exporter of 4th Generation Warfare Instability (United States)


    e.g., Colombia and Peru, to date); and, • Diplomatic war/media war/conventional war (e.g., Algeria, 1954-62). 13 Any one of the war, trade war, psychological war, network ( virus ) war, cyber war, chemical-biological-radiological war, etc. Professional soldiers to the insurgent and drug trafficking Revo- lutionary Armed Forces of Colombia (FARC), Ira- 23 nian surrogate and terrorist Hezbollah

  17. Explosive and chemical threat detection by surface-enhanced Raman scattering: A review

    DEFF Research Database (Denmark)

    Hakonen, Aron; Andersson, Per Ola; Schmidt, Michael Stenbæk;


    Acts of terror and warfare threats are challenging tasks for defense agencies around the world and of growing importance to security conscious policy makers and the general public. Explosives and chemical warfare agents are two of the major concerns in this context, as illustrated by the recent...... Boston Marathon bombing and nerve gas attacks on civilians in the Middle East. To prevent such tragic disasters, security personnel must be able to find, identify and deactivate the threats at multiple locations and levels. This involves major technical and practical challenges, such as detection...... progressively better, smaller and cheaper, and can today be acquired for a retail price close to 10,000 US$. This contribution aims to give a comprehensive overview of SERS as a technique for detection of explosives and chemical threats. We discuss the prospects of SERS becoming a major tool for convenient in...

  18. Polarimetry and infrared spectroscopy in the detection of low-volatility chemical threats (United States)

    Petryk, Michael W. P.; Marenco, Armando J.


    The polarization modulation infrared reflection absorption spectroscopy (PMIRRAS) spectra of the nerve agents GB (O-isopropyl methylphosphonofluoridate) and GF (cyclohexyl methylphoshonofluoridate) were recorded for the first time. A comparison of these spectra with the nerve agent VX (ethyl S-2-diisopropylaminoethyl methylphosphonothiolate) and the spectra of some trialkyl phosphates indicates that it is easy to distinguish between chemical warfare agents and simulants on militarily-relevant surfaces using PMIRRAS.

  19. Net-Centric Warfare 2.0: Cloud Computing and the New Age of War (United States)


    gets credit for its part , the mashup must be provided free of charge, etc.).27 Google even provides documentation showing the user how to build a...created a Facebook group called "Un Millon de Voces Contra las FARC" ("One Million Voices against the FARC")… In less than 12 hours the group had more...key parts of the multibillion-dollar effort teetered on the brink of cancellation.”50 Network Centric Warfare as currently envisioned by the


    Directory of Open Access Journals (Sweden)

    G.K.B. Barron


    Full Text Available Lawrence was basically an academic thrown into the hurly-burly of leading an Arab revolt against Turkish domination. It could be said that the war in the Middle East was a sideshow of the First World War and Lawrence's part was a ' ... sideshow to the sideshow'l Why then has Lawrence been remembered when greater military men have been forgotten? The romanticism of his exploits are surely the reason, and yet the fact that he is the first modern theorist and possibly the "father" of modern revolutionary warfare, tends to be forgotten.

  1. New concepts and their applications in underwater acoustic warfare simulation system

    Institute of Scientific and Technical Information of China (English)

    DONG Yangze; YAO Lan


    An underwater acoustic warfare simulation system (UAWSS) with a structure of high level architecture (HLA) is studied based upon a previous research project. With the experience and lessons learned, some new concepts are adopted in the implementation of UAWSS according to the essence of simulation and the objective of the system, among which are simulation synthetic environment, signal processing at other simulation nodes, decomposition of underwater sound channel, channel varying law and rules on system and parts evaluation, etc. Applications of these new ideas show that they are effective.

  2. Smart phones: platform enabling modular, chemical, biological, and explosives sensing (United States)

    Finch, Amethist S.; Coppock, Matthew; Bickford, Justin R.; Conn, Marvin A.; Proctor, Thomas J.; Stratis-Cullum, Dimitra N.


    Reliable, robust, and portable technologies are needed for the rapid identification and detection of chemical, biological, and explosive (CBE) materials. A key to addressing the persistent threat to U.S. troops in the current war on terror is the rapid detection and identification of the precursor materials used in development of improvised explosive devices, homemade explosives, and bio-warfare agents. However, a universal methodology for detection and prevention of CBE materials in the use of these devices has proven difficult. Herein, we discuss our efforts towards the development of a modular, robust, inexpensive, pervasive, archival, and compact platform (android based smart phone) enabling the rapid detection of these materials.

  3. Chemical Emergencies (United States)

    When a hazardous chemical has been released, it may harm people's health. Chemical releases can be unintentional, as in the case of an ... the case of a terrorist attack with a chemical weapon. Some hazardous chemicals have been developed by ...

  4. Three-dimensional visualization and control of electronic warfare (EW) payloads (United States)

    Kirsch, Patricia; Tremper, David; Cortesi, Roger


    The proliferation of unmanned vehicles carrying tactical payloads in the battle-space has accelerated the need for user-friendly visualization with graphical interfaces to provide remote command and control. Often these platforms and payloads receive their control functions from command centers located half a world away via satellite communications. Operators require situational awareness tools capable of graphically presenting the remote battlefield asset positions and collected sensor data. Often these systems use 2D software mapping tools in conjunction with video for real time situational awareness. The Special Projects Group (SPG) in the Tactical Electronic Warfare Division of the U.S. Naval Research Laboratory has been developing an operator control interface called the Jammer Control Station (JCS) to provide 3D battle-space visualization with built-in, remote EW payload command and control (C2) capabilities. The JCS interface presents the operator with graphic depictions of both the platforms' states and the RF environment. Text based messaging between the JCS and the EW payload reduces the impact of the system on the available bandwidth. This paper will discuss the use of the SIMDIS 3-D visualization tool as a real-time command and control interface for electronic warfare (EW) payloads.

  5. Investigating the Relationship Between Drone Warfare and Civilian Casualties in Gaza

    Directory of Open Access Journals (Sweden)

    Dr. Ann Rogers


    Full Text Available Unmanned aerial vehicles (UAVs, better known as drones, are increasingly touted as ‘humanitarian’ weapons that contribute positively to fighting just wars and saving innocent lives. At the same time, civilian casualties have become the most visible and criticized aspect of drone warfare. It is argued here that drones contribute to civilian casualties not in spite of, but because of, their unique attributes. They greatly extend war across time and space, pulling more potential threats and targets into play over long periods, and because they are low-risk and highly accurate, they are more likely to be used. The assumption that drones save lives obscures a new turn in strategic thinking that sees states such as Israel and the US rely on large numbers of small, highly discriminating attacks applied over time to achieve their objectives. This examination of Israel’s 2014 war in Gaza argues that civilian casualties are not an unexpected or unintended consequence of drone warfare, but an entirely predictable outcome.

  6. Bioarchaeological investigation of ancient Maya violence and warfare in inland Northwest Yucatan, Mexico. (United States)

    Serafin, Stanley; Lope, Carlos Peraza; Uc González, Eunice


    This study investigates evidence of changes and continuities in ancient Maya violence and warfare in inland northwest Yucatan, Mexico from the Middle Preclassic (600-300 BC) to the Postclassic (AD 1050-1542) through bioarchaeological analysis of cranial and projectile trauma. It is hypothesized that the frequency of violence increases before the Classic Maya collapse and remains high during the Postclassic period. It is also hypothesized that the flat, open terrain was conducive to warfare and resulted in higher trauma frequencies than in other parts of the Maya area. Results show that the frequency of cranial trauma decreases before the Classic collapse and increases in the Postclassic, partially matching the expected chronological trends. The frequency of cranial trauma does not differ significantly from other Maya regions but the pattern does: for all periods, males have more healed injuries than females and they are concentrated on the left side of the anterior of the skull. Some injuries appear to be from small points hafted in wooden clubs. In addition, projectile trauma is evident in a scapula with an embedded arrowhead tip, the first such case reported in a Maya skeleton. Overall, these results suggest greater reliance on open combat and less on raids in this region compared with other parts of the Maya area, possibly due to the flat, open terrain, though the identification of perimortem trauma in both women and men indicates surprise raids on settlements were also practiced.

  7. Academic Training Lectures | Stuxnet and Cyber-Warfare | 13-14 January 2016

    CERN Multimedia


    Please note that the next series of Academic Training Lectures will take place on 13 and 14 January 2016. The lectures will be given by Gian Piero Siroli (Università e INFN, Bologna (IT))   Stuxnet and Cyber-Warfare (1/2)​ on Wednesday, 13 January from 11 a.m. to 12 p.m. Stuxnet and Cyber-Warfare (2/2) on Thursday, 14 January from 11 a.m. to 12 p.m. at CERN, Council Chamber (503-1-001)  Description: The first part of the lecture is devoted to the description of the Stuxnet worm, the first cyber-weapon whose existence has been made public, discovered in 2010 and targeting a specific industrial control system; the worm is responsible for the damaging of many centrifuges at an uranium enrichment facility, with the goal of sabotaging Iran&...

  8. An Empirical Examination of the Warfare Metaphor with Respect to Pre-Service Elementary Teachers (United States)

    Cobern, William W.; Loving, Cathleen C.; Davis, Edward B.; Terpstra, Jeff


    Since its origination in the late nineteenth century, the warfare metaphor has been used to characterize the relationship between science and religion, especially orthodox Christianity. Though thoroughly discredited by historians of science, the ideological descendants of Thomas Huxley, who spoke of science in quasi-religious terms, have kept the warfare metaphor alive. On the other hand, there are substantial numbers of Christians who at least appear to oppose science given their high-profile opposition to the general theory of evolution. The research reported in this paper asked, "Does anti-science sentiment increase with increasing orthodox Christian belief?" Two validated, published instruments were used: The Thinking about Science Survey Instrument and the Christian Fundamentalist Belief Scale. The subjects for the study were 545 preservice elementary teachers. The analysis did not show that anti-science sentiment increases with increasing Christian belief. Subjects with strong Christian beliefs were found to be just as supportive of science, if not more so, than subjects with no Christian beliefs. The study concludes with a caution against projecting attitudes toward science "on the whole" based on attitudes specifically toward evolution when working with preservice elementary teachers. Such a projection could well be counterproductive. The study has implications for other modern countries having highly religious populations such as Turkey.

  9. Implications for studying team cognition and team performance in network-centric warfare paradigms. (United States)

    Krueger, Gerald P; Banderet, Louis E


    Network-centric warfare's (NCW) information-rich systems involving sophisticated sensors, tracking systems, smart weapons, and enhanced digital communications threaten to overload combatants with voluminous amounts of data. It is unclear whether warfighters will perceive such extensive data as actionable information to which they will respond accurately in a timely enough manner. Members of small teams in command and control centers, operating in crew-served vehicles, or simply "grunting it out" as ground-pounding infantrymen, may be disparately separated by space, but will communicate and be connected by electronic linkages, e.g., radio, text messages, situation displays, or global positioning data. However, team members will also have to remember shared mental models of tasks at hand, pay attention to and share common situation awareness in complex operational environments, perform team cognition and team coordination, and integrate both lower and higher cognitive processes with those of team behaviors. Such exceptional capabilities are required more now than ever before; such capabilities today are far from assured. After two workshops to establish performance metrics for assessing cognitive performance of military personnel in NCW, this preface introduces five manuscripts addressing team cognition and team performance from both a theoretical and a practical perspective. The authors of this preface question if NCW, and perhaps the politico-social ramifications of modern warfare, have already outstripped behavioral scientists' approach to researching team cognition and team performance-expertise that is so crucially needed for combatants on the rapidly changing 21st-century battlegrounds.

  10. Speed of adaptation and genomic footprints of host-parasite coevolution under arms race and trench warfare dynamics. (United States)

    Tellier, Aurélien; Moreno-Gámez, Stefany; Stephan, Wolfgang


    Coevolution between hosts and their parasites is expected to follow a range of possible dynamics, the two extreme cases being called trench warfare (or Red Queen) and arms races. Long-term stable polymorphism at the host and parasite coevolving loci is characteristic of trench warfare, and is expected to promote molecular signatures of balancing selection, while the recurrent allele fixation in arms races should generate selective sweeps. We compare these two scenarios using a finite size haploid gene-for-gene model that includes both mutation and genetic drift. We first show that trench warfare do not necessarily display larger numbers of coevolutionary cycles per unit of time than arms races. We subsequently perform coalescent simulations under these dynamics to generate sequences at both host and parasite loci. Genomic footprints of recurrent selective sweeps are often found, whereas trench warfare yield signatures of balancing selection only in parasite sequences, and only in a limited parameter space. Our results suggest that deterministic models of coevolution with infinite population sizes do not predict reliably the observed genomic signatures, and it may be best to study parasite rather than host populations to find genomic signatures of coevolution, such as selective sweeps or balancing selection.

  11. Groundwater geochemical and selected volatile organic compound data, Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington, July 2015 (United States)

    Huffman, Raegan L.


    Previous investigations indicate that concentrations of chlorinated volatile organic compounds (CVOCs) are substantial in groundwater beneath the 9-acre former landfill at Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington. The U.S. Geological Survey has continued to monitor groundwater geochemistry to ensure that conditions remain favorable for contaminant biodegradation as specified in the Record of Decision for the site.

  12. Warfare has changed - so should have methods: Ammunition and weapon performance induced operational risk and safety issues

    NARCIS (Netherlands)

    Verhagen, T.L.A.; Voorde, M.J. van de


    Warfare has changed. Out-of-area operations have increased the awareness that we are unfamiliar with the performance of the current conventional medium and large calibre ammunitions in day-to-day practice. Current ammunition is primarily developed and procured to defeat the traditional ‘steel’ targe

  13. An Assessment of the Effectiveness of Computer-based Training for Newly Commissioned Surface Warfare Division Officers (United States)


    Chief of Naval Operations Surface Warfare Directorate. (2002, June 15). Navigation, seamanship and shiphandling training requirements document...unlimited. Prepared for: Naval Postgraduate School, Monterey, California 93943 An Assessment of the Effectiveness of Computer-based Training...Stephen Mehay, Professor With the assistance of Carol Stoker and Robert Paynter Naval Postgraduate School Naval Postgraduate School

  14. Global Survey of Research and Capabilities in Genetically Engineered Organisms That Could be Used in Biological Warfare or Bioterrorism (United States)


    advances (summarized in Section 4) that could facilitate or at least inspire the pursuit of biological warfare capabilities. We share the opinion that...a) Infectious Diseases Control Unit of the Direction de la sante publique , Montreal Chest Institute, Montreal Division of Infectious and

  15. 76 FR 10522 - Naval Surface Warfare Center, Upper Machodoc Creek and the Potomac River, Dahlgren, VA; Danger Zone (United States)


    ... and the Potomac River, Dahlgren, VA; Danger Zone AGENCY: U.S. Army Corps of Engineers, DoD. ACTION... danger zone in the vicinity of Naval Surface Warfare Center, Dahlgren, in King George County, Virginia..., and expands the boundaries of a portion of the danger zone. The amendment is necessary to protect...

  16. The Venus "Shell-over-Star" hieroglyph and Maya warfare: An examination of the interpretation of a Mayan symbol (United States)

    Voit, Claudia Ann

    For decades, Maya scholars have associated the Mayan "Shell-Star" (also referred to as "Star-War") hieroglyph with Maya warfare. Put forward by scholars such as Floyd Lounsbury and David Kelley, and later advanced by Linda Schele, David Freidel, Ian Graham, Peter Matthews, Anthony Aveni and others, there are now dozens of published articles and chapters relating the hieroglyph to Venus and warfare. Venus is one of the most notable celestial objects outside of the Sun and Moon and was highly visible to the inhabitants of the Maya world. The Dresden Codex (an astronomical almanac) contains important information about the planet Venus, and the calendar section was deciphered by the librarian and mathematician, Ernst Förstemann in the late 1800s. In his decipherment, he deduced that the numbers contained in the tables must be connected to the orbital period of the planet. There is no other planet with the same orbital period 3 as Venus. Förstemann suggested that the decoded astronomy tables were used by the Maya to determine when to wage war. This interpretation, along with others, like Floyd Lounsbury`s study of Venus and the Long Count date at Bonampak were the seeds that have led to methodological errors that first began to take root in Maya research. The idea of the Venus association with warfare took hold and continues to propagate. Many scholars continue to assert that the "shell-star" glyph is related to warfare events. Others, like Gerardo Aldana, and Stanley Guenter, have recently come forward to reexamine and question the hieroglyph and its relationship, if any, to Maya warfare. I suggest, further, that methodological errors may have occurred along the way. I propose that these errors include data lost in translation, and inaccurate translations. In addition, the statistical analysis of Venus cycles has weak points. If this identification of the errors is correct, we need to re-evaluate the weakened foundation on which we are building our assertions about

  17. Love-Wave Sensors Combined with Microfluidics for Fast Detection of Biological Warfare Agents (United States)

    Matatagui, Daniel; Fontecha, José Luis; Fernández, María Jesús; Gràcia, Isabel; Cané, Carles; Santos, José Pedro; Horrillo, María Carmen


    The following paper examines a time-efficient method for detecting biological warfare agents (BWAs). The method is based on a system of a Love-wave immunosensor combined with a microfluidic chip which detects BWA samples in a dynamic mode. In this way a continuous flow-through of the sample is created, promoting the reaction between antigen and antibody and allowing a fast detection of the BWAs. In order to prove this method, static and dynamic modes have been simulated and different concentrations of BWA simulants have been tested with two immunoreactions: phage M13 has been detected using the mouse monoclonal antibody anti-M13 (AM13), and the rabbit immunoglobulin (Rabbit IgG) has been detected using the polyclonal antibody goat anti-rabbit (GAR). Finally, different concentrations of each BWA simulants have been detected with a fast response time and a desirable level of discrimination among them has been achieved. PMID:25029282

  18. A war psychiatry approach to warfare in the Middle Byzantine period. (United States)

    Ntafoulis, Pavlos


    Combat stress cases were traced in historical texts and military manuals on warfare from the Middle Byzantine period; they were mainly labelled as cowardice. Soldiers suffered from nostalgia or exhaustion; officers looked stunned, or could not speak during the battle. Cruel punishments were often enforced. Suicide and alcohol abuse were rarely mentioned. The Byzantines' evacuation system for battle casualties was well organized. Psychological operations were conducted and prisoners-of-war were usually part of them. The Byzantine army had 'parakletores', officers assigned to encourage soldiers before combat. The leaders dealt with combat stress by using their rhetoric skills and emphasizing religious faith in eternal life. The treatment of the 'cowards' was rather similar to modern war psychiatry principles of treatment. No description of PTSD was found.

  19. The art of antibacterial warfare: Deception through interference with quorum sensing-mediated communication. (United States)

    Rampioni, Giordano; Leoni, Livia; Williams, Paul


    Almost a century on from the discovery of penicillin, the war against bacterial infection still rages compounded by the emergence of strains resistant to virtually every clinically approved antibiotic and the dearth of new antibacterial agents entering the clinic. Consequently there is renewed interest in drugs which attenuate virulence rather than bacterial growth. Since the metaphors of warfare are often used to describe the battle between pathogen and host, we will describe in such a context, the molecular communication (quorum sensing) mechanisms used by bacteria to co-ordinate virulence at the population level. Recent progress in exploiting this information through the design of anti-virulence deception strategies that disrupt quorum sensing through signal molecule inactivation, inhibition of signal molecule biosynthesis or the blockade of signal transduction and their advantages and disadvantages are considered.

  20. Approximation and Filtering Techniques for Navigation Data in Time-critical Electronic Warfare Systems

    Directory of Open Access Journals (Sweden)

    Vanitha D.


    Full Text Available This paper presents a holistic solution to the navigation requirements in a time critical electronic warfare systems like missile warning systems (MWS. In a passive MWS using IR sensors the efficiency of the system is determined by attributes such as low false alarm rate, minimal response time and ability to track different IR radiating objects by association and correlation of consecutive detections through time. Such a system is required to be supported by a navigation system capable of accurate estimation of the aircraft position, attitude angles and altitude. In this paper, estimation techniques used to accurately calculate aircraft navigation data at the time of capture of IR frames are discussed. The paper discusses about synchronization of INGPS, IR sensors & Processor on to same timeline. The paper also intends to evaluate the performance of wavelet transform filter in effective elimination of noise in navigation parameters like acceleration and attitude angle rates for a better estimation of position and attitude.


    Directory of Open Access Journals (Sweden)

    Petrişor JALBĂ


    Full Text Available Within the framework of the current revolution in military affairs, at the End of the Cold War a new concept was born: the concept of War Based on Computer Networking or NCW Network Centric-Warfare which was established as a central element of modern military operations. Determined by theprogress recorded in the field of communication systems of all types, technology of information (HI-Tech, IT, war based on computer networking brings a change in the war paradigm and its inherent components In this respect, logistics based on computer networking represents one of the ways in which the reality of the battlefield is preserved which enhances the joint perspective upon the military forces.

  2. Love-Wave Sensors Combined with Microfluidics for Fast Detection of Biological Warfare Agents

    Directory of Open Access Journals (Sweden)

    Daniel Matatagui


    Full Text Available The following paper examines a time-efficient method for detecting biological warfare agents (BWAs. The method is based on a system of a Love-wave immunosensor combined with a microfluidic chip which detects BWA samples in a dynamic mode. In this way a continuous flow-through of the sample is created, promoting the reaction between antigen and antibody and allowing a fast detection of the BWAs. In order to prove this method, static and dynamic modes have been simulated and different concentrations of BWA simulants have been tested with two immunoreactions: phage M13 has been detected using the mouse monoclonal antibody anti-M13 (AM13, and the rabbit immunoglobulin (Rabbit IgG has been detected using the polyclonal antibody goat anti-rabbit (GAR. Finally, different concentrations of each BWA simulants have been detected with a fast response time and a desirable level of discrimination among them has been achieved.

  3. Love-wave sensors combined with microfluidics for fast detection of biological warfare agents. (United States)

    Matatagui, Daniel; Fontecha, José Luis; Fernández, María Jesús; Gràcia, Isabel; Cané, Carles; Santos, José Pedro; Horrillo, María Carmen


    The following paper examines a time-efficient method for detecting biological warfare agents (BWAs). The method is based on a system of a Love-wave immunosensor combined with a microfluidic chip which detects BWA samples in a dynamic mode. In this way a continuous flow-through of the sample is created, promoting the reaction between antigen and antibody and allowing a fast detection of the BWAs. In order to prove this method, static and dynamic modes have been simulated and different concentrations of BWA simulants have been tested with two immunoreactions: phage M13 has been detected using the mouse monoclonal antibody anti-M13 (AM13), and the rabbit immunoglobulin (Rabbit IgG) has been detected using the polyclonal antibody goat anti-rabbit (GAR). Finally, different concentrations of each BWA simulants have been detected with a fast response time and a desirable level of discrimination among them has been achieved.

  4. Research on Electronic Warfare Operational Simulation Experiment Design%电子对抗作战仿真实验设计研究

    Institute of Scientific and Technical Information of China (English)

    陶玉; 耿松涛; 王枭犇


      针对目前电子对抗作战仿真实验设计中存在的突出问题,对电子对抗作战仿真实验设计进行研究。介绍我军电子对抗作战仿真实验设计的发展现状,分析电子对抗作战仿真实验设计中存在的问题,提出结合实验目的规范电子对抗作战仿真实验设计的思路。该研究为实现电子对抗作战仿真实验设计的规范化、标准化做出了有益探索。%Aiming at the problems existed in designing electronic warfare operational simulation experiment, electronic warfare operational simulation experiment design is researched. It introduces the development situation of PLA’s electronic warfare operational simulation experiment firstly, analyses the problems in designing electronic warfare operational simulation experiment, and brings a design idea that combines it with experiment goals for electronic warfare operational simulation experiment. The research can offer reference for realize the normalization and standardization of electronic warfare campaign simulation experimental design.

  5. Clinical and forensic signs related to chemical burns: a mechanistic approach. (United States)

    Dinis-Oliveira, Ricardo Jorge; Carvalho, Félix; Moreira, Roxana; Proença, Jorge Brandão; Santos, Agostinho; Duarte, José Alberto; Bastos, Maria de Lourdes; Magalhães, Teresa


    This manuscript highlights and critically analyses clinical and forensic signs related to chemical burns. Signs that may lead to suspicion of a particular chemical are thoroughly discussed regarding its underlying mechanisms. Burns due to sulfuric, hydrofluoric, nitric, hydrochloric (muriatic) and acetic (including derivatives) acids, hydrogen sulphide, sodium (caustic soda) and calcium (cement) hydroxides, paraquat, burns after inflation and rupture of airbags, povidone-iodine, chlorhexidine/alcohol (in preterm infants), laxatives, and vesicants (warfare agents), will be reviewed since these are the most common agents found in daily practice, for which relevant and timed information may be helpful in formulating an emergency treatment protocols and toxicological analysis.

  6. Bioterrorism and Biological Warfare, from Past to the Present: A classic review

    Directory of Open Access Journals (Sweden)

    Majid Zare Bidaki


    Full Text Available Bioterrorism is defined as any terrorist action of intentional release or dissemination of highly pathogenic biological agents, including a variety of microorganisms or biological toxins. With the growing threat of terrorism, is necessary that the potential danger of various microorganisms – as a powerful tool of aggression and threat- to be taken seriously. This review tries to explain the concept of biological weapons and their historical development process with an emphasis on efforts to control the proliferation of these types of weapons over the last century. Potential impact of infectious diseases on people and armed forces was known from since 600 BC. Using the victims of the plague as a weapon in medieval warfare and spread of smallpox as a weapon during the war against the Indians when initially America was discovered, the development of biological weapons during the World War I, World War II and the Cold War, and even since the beginning of the third millennium, all show the strategic importance of pathogenic microorganisms as a deterrent power for the superiority of some governments and cults. Historical attempts to use infectious diseases as biological weapons reveal that the distinction between a natural outbreak of an infectious disease and that of a deliberate biological attack is very difficult. Abusing this characteristic of infectious diseases has made it possible for the purposes of superiority. International agreements to control the development of biological weapons, such as “the 1925 Geneva Protocol” and “the Convention on the Prohibition of the Development, Production and Stockpiling of Biological and Toxic Weapons” have not been able to control the development and using of biological warfare.  The current paper is a classic review (Overview article aiming at increasing the knowledge and awareness of people especially of health authorities and government officials.

  7. Naval electronic warfare simulation for effectiveness assessment and softkill programmability facility (United States)

    Lançon, F.


    The Anti-ship Missile (ASM) threat to be faced by ships will become more diverse and difficult. Intelligence, rules of engagement constraints, fast reaction-time for effective softkill solution require specific tools to design Electronic Warfare (EW) systems and to integrate it onboard ship. SAGEM Company provides decoy launcher system [1] and its associated Naval Electronic Warfare Simulation tool (NEWS) to permit softkill effectiveness analysis for anti-ship missile defence. NEWS tool generates virtual environment for missile-ship engagement and counter-measure simulator over a wide spectrum: RF, IR, EO. It integrates EW Command & Control (EWC2) process which is implemented in decoy launcher system and performs Monte-Carlo batch processing to evaluate softkill effectiveness in different engagement situations. NEWS is designed to allow immediate EWC2 process integration from simulation to real decoy launcher system. By design, it allows the final operator to be able to program, test and integrate its own EWC2 module and EW library onboard, so intelligence of each user is protected and evolution of threat can be taken into account through EW library update. The objectives of NEWS tool are also to define a methodology for trial definition and trial data reduction. Growth potential would permit to design new concept for EWC2 programmability and real time effectiveness estimation in EW system. This tool can also be used for operator training purpose. This paper presents the architecture design, the softkill programmability facility concept and the flexibility for onboard integration on ship. The concept of this operationally focused simulation, which is to use only one tool for design, development, trial validation and operational use, will be demonstrated.

  8. Hydrogeologic and chemical data for the O-Field area, Aberdeen Proving Ground, Maryland (United States)

    Nemoff, P.R.; Vroblesky, D.A.


    O-Field, located at the Edgewood area of Aberdeen Proving Ground , Maryland, was periodically used for disposal of munitions, waste chemicals, and chemical-warfare agents from World War II through the 1950' s. This report includes various physical, geologic, chemical, and hydrologic data obtained from well-core, groundwater, surface water, and bottom-sediment sampling sites at and near the O-Field disposal area. The data are presented in tables and hydrographs. Three site-location maps are also included. Well-core data include lithologic logs for 11 well- cluster sites, grain-size distributions, various chemical characteristics, and confining unit characteristics. Groundwater data include groundwater chemistry, method blanks for volatile organic carbon, available data on volatile and base/neutral organics, and compilation of corresponding method blanks, chemical-warfare agents, explosive-related products, radionuclides, herbicides, and groundwater levels. Surface-water data include field-measured characteristics; concentrations of various inorganic constituents including arsenic; selected organic constituents with method blanks; detection limits of organics; and a compilation of information on corresponding acids, volatiles, and semivolatiles. Bottom- sediment data include inorganic properties and constituents; organic chemistry; detection limits for organic chemicals; a compilation of information on acids, volatiles, and semivolatiles; and method blanks corresponding to acids, volatiles, and semivolatiles. A set of 15 water- level hydrographs for the period March 1986 through September 1987 also is included in the report. (USGS)

  9. Decontamination of chemical agents from drinking water infrastructure: a literature review and summary. (United States)

    Szabo, Jeff; Minamyer, Scott


    This report summarizes the current state of knowledge on the persistence of chemical contamination on drinking water infrastructure (such as pipes) along with information on decontamination should persistence occur. Decontamination options for drinking water infrastructure have been explored for some chemical contaminants, but important data gaps remain. In general, data on chemical persistence on drinking water infrastructure is available for inorganics such as arsenic and mercury, as well as select organics such as petroleum products, pesticides and rodenticides. Data specific to chemical warfare agents and pharmaceuticals was not found and data on toxins is scant. Future research suggestions focus on expanding the available chemical persistence data to other common drinking water infrastructure materials. Decontaminating agents that successfully removed persistent contamination from one infrastructure material should be used in further studies. Methods for sampling or extracting chemical agents from water infrastructure surfaces are needed.

  10. Electronic Warfare (United States)


    2) The use of the EMS is essential to control the OE during all military operations. The transfer of information from the collectors to the...frequencies used for satellite communications (SATCOM); the effects of solar activities such as sunspots, solar flares, and atmospheric fluctuations, alteration, suppression, absorption , denial, enhancement, or reflection of EM energy in a manner intended to convey misleading

  11. Hybrid Warfare (United States)


    failed Strategic Hamlet program,125 expanded advisory efforts,126 and prompt- ing the Diem regime in Saigon to invest in paramilitary Territorial...acceleration of resources guided by CORDS’s contentious Hamlet Evaluation System.175 The effect of the APC is that Communist forces began to rely on...138; Fall, Street Without Joy, 363. The Strategic Hamlet program was an effort to extend governance to the countryside and provide a local counter

  12. Nuclear warfare

    CERN Multimedia



    Le Prof.Broda a étudié à Vienne et Berlin et a travaillé pendant la dernière guerre mondiale en Grande Bretagne pour le conseil de la recherche médicale, notamment sur la chimie de la vision. Il est maintenant Prof. de la chimie, physique et radiochimie à l'Université de Vienne, où il concentre ses travaux sur les méchanisme de transport d'énergie à travers les cellules de membranes.

  13. Mobile Warfare

    Institute of Scientific and Technical Information of China (English)



    @@ In 1984, US computer manufacturer Apple spent almost USD 1.5 million on a lavish, Ridley Scott-directed commercial for its new Macintosh 128k personal computer. A year later, Microsoft released Microsoft Windows for IBM PC, signaling the start of the battle for domi-nation of the personal computer market which has waged ever since.

  14. Air Warfare (United States)


    undoubtedly begat the shield; poisonous gases were countered by the mask. Surely men on the surface of the earth will not have to submit to violent air, production methods and cost of helium are given in “Balloon and Airship Gases ,” a volume of the Ronald Aeronautic Library. 5 More complete...becomes and more inse - cure. We shall see later that even some of the men who were advancing in the path prescribed by the principle of mass

  15. Application of high-frequency ventilation to treatment of chemical-warfare casualties: Animal and theoretical studies (application of high-frequency transtracheal jet ventilation to treatment of chemical-warfare casualties). Final report, March 1983-December 1986

    Energy Technology Data Exchange (ETDEWEB)

    Abbrecht, P.H.; Bryant, H.J.; Kyle, R.


    The objective of this work was to evaluate the effectiveness of transtracheal jet ventilation in organophosphate-challenged animals. Preliminary studies were done in normal canines to define the effects of ventilator operating parameters on respiratory gas exchange. Nine normal dogs, anesthetized with sodium pentobarbital, were ventilated through an eight gauge cricothyrotomy cannula using a controller that allowed separate setting of drive pressure, duty cycle, and frequency. Arterial (partial pressure of oxygen) and (partial pressure of carbon dioxide) were measured after achieving steady state gas exchange at 15-22 different combinations of drive pressure, duty cycle, and frequency in each dog. There were slight increases in PaCO2 and larger decreases in arterial oxygen partial pressure as frequency was increased from 10 to 200 cycles/min. Increases in drive pressure and duty cycle resulted in reductions in PaCO2 and increases in PaO2.

  16. Lightweight autonomous chemical identification system (LACIS) (United States)

    Lozos, George; Lin, Hai; Burch, Timothy


    Smiths Detection and Intelligent Optical Systems have developed prototypes for the Lightweight Autonomous Chemical Identification System (LACIS) for the US Department of Homeland Security. LACIS is to be a handheld detection system for Chemical Warfare Agents (CWAs) and Toxic Industrial Chemicals (TICs). LACIS is designed to have a low limit of detection and rapid response time for use by emergency responders and could allow determination of areas having dangerous concentration levels and if protective garments will be required. Procedures for protection of responders from hazardous materials incidents require the use of protective equipment until such time as the hazard can be assessed. Such accurate analysis can accelerate operations and increase effectiveness. LACIS is to be an improved point detector employing novel CBRNE detection modalities that includes a militaryproven ruggedized ion mobility spectrometer (IMS) with an array of electro-resistive sensors to extend the range of chemical threats detected in a single device. It uses a novel sensor data fusion and threat classification architecture to interpret the independent sensor responses and provide robust detection at low levels in complex backgrounds with minimal false alarms. The performance of LACIS prototypes have been characterized in independent third party laboratory tests at the Battelle Memorial Institute (BMI, Columbus, OH) and indoor and outdoor field tests at the Nevada National Security Site (NNSS). LACIS prototypes will be entering operational assessment by key government emergency response groups to determine its capabilities versus requirements.

  17. Continuous Acoustic Sensing With an Unmanned Aerial Vehicle System for Anti-Submarine Warfare in a High-Threat Area (United States)


    ACOUSTIC SENSING WITH AN UNMANNED AERIAL VEHICLE SYSTEM FOR ANTI- SUBMARINE WARFARE IN A HIGH-THREAT AREA by Loney R. Cason III December 2015...13. ABSTRACT (maximum 200 words) An unmanned aerial vehicle system called the “Aqua-Quad,” an ultra-long-endurance hybrid design, developed by...sonobuoy, unmanned aerial vehicle 15. NUMBER OF PAGES 51 16. PRICE CODE 17. SECURITY CLASSIFICATION OF REPORT Unclassified 18. SECURITY

  18. Chemical Warfare Agent Decontamination Efficacy Testing Large-Scale Chamber mVHP (registered trademerk) Decontamination System Evaluation (United States)


    06 Wipe HD 500 30 27.1 ±0.3 18.5 ± 1.6 24 01- Mar -06 Wipe HD 500 30 27.2 ±0.3 12.2 ±1.6 31 (HDE) 22-Feb-06 Extr. Eff. HD 0 0 N/A N/A 7 08-Dec-05...19.1 ±3.2 17 25-Jan-06 Efficacy VX 500 30 27.4 ±0.5 17.7 ±1.4 34(17R) 15- Mar -06 Efficacy VX 500 30 27.8 ±0.3 15.9 ±1.4 30 27- Mar -06 Efficacy VX 500 30...flow - 20 mL/min purge time - 1 min minimum carrier pressure - 5 psi purge flow - 20 mL/min ola split flow - 20 mL/min oven temperature 1 - 250 °C

  19. Infrared Spectra and Binding Energies of Chemical Warfare Nerve Agent Simulants on the Surface of Amorphous Silica (United States)


    such as DMMP and DFP. While many groups have investigated the fundamental interactions between select organophosphorous compounds and silica, many...substituents within organophosphorous compounds (a key characteristic of the CWAs sarin and soman7) affect the strength of hydrogen-bond formation on silica...the bonding geometries and electronic structure of the organophosphorous compounds on silica. Furthermore, the calculations enable us to explore

  20. Immobilization of Enzymes in Nanoporous Host Materials: A Nanobiotechnological Approach to Decontamination and Demilitarization of Chemical and Biological Warfare Agents (United States)


    Type IV with H2 hysteresis loop, typical of mesoporous materials. The incorporation of the methyl group into the silica matrix (OPAA-HF series samples...compared to that of the immobilized enzymes in TMOS-derived materials. The non-surfactant template pathway58-59 to the mesoporous silica materials...biocatalyst OPAA into mesoporous silica host materials of various compositions. OPAA was chosen owing to its ability to catalyze the hydrolysis of highly

  1. Report of Investigation: The Presence of Biological and Chemical Warfare Materiel at AFMC Bases within the United States (United States)


    pungent and stinging odor Phosgene (CG)-colorless gas with odor of new mown hay or green corn Chloroacetophenone (CN)-solid with fragrant odor...agents can cause coughing, nausea, vomiting, irritation, burning sensation , swelling of the eyes, itching, redness and blisters on the skin, and acute

  2. The Concentration Probability Density Function With Implications for Probabilistic Modeling of Chemical Warfare Agent Detector Responses for Source Reconstruction (United States)


    probabiliste concernant la réponse du détecteur d’agents chimiques , dans le contexte du problème de la reconstruction de source. ii DRDC Suffield TR 2008...quantité d’agent émis et l’heure de l’émission détectée par un réseau de capteurs CBR. Pour être en mesure de combler cette lacune, le Programme de...tions CBR provenant de réseaux de capteurs éloignés pouvant être déployés et ayant des données de modèles de concentrations obtenues par des

  3. Multifunctional Ultra-High Vacuum Apparatus for Studies of the Interactions of Chemical Warfare Agents on Complex Surfaces (United States)


    on gamma alumina surfaces. This work was followed by other investigations of organophosphate CWA decomposition on alumina.35 In addition, Wagner and...nm particle di- ameter) was chosen as the first surface to study because the adsorption of many organophosphate molecules (simu- lants) to silica has...Kondratyuk, and J. T. Yates, “Photooxidation of a mus- tard gas simulant over TiO2-SiO2 mixed-oxide photocatalyst: Site poison - ing by oxidation products

  4. Evaporation Rates of Chemical Warfare Agents Measured using 5 cm Wind Tunnels III. Munition-Grade Sulfur Mustard on Concrete (United States)


    from glass occurred from a sessile droplet with a constant base and the contact angle changing during the evaporation.1" Previous studies also...Hg Parameters Adv. Contact Angle : 130.000 degrees Rec. Contact Angle : Hg Surface Tension: 485.000 dynes/cm Hg Density: Low Pressure...temperature, drop size, and air flow rate using the same instrumentation as prior studies on glass and sand. The evaporation rate increased with higher

  5. Developmental Toxic Effects of Exposure to Chemical Warfare Nerve Agents in Rats: Effects on Brain and Behavior (United States)


    stimulation of acetylcholine receptors. Common consequences of this cholinergic crisis include seizure activity, neuronal damage and behavioral deficits. The...current study, male and female rats exposed to sarin (GB) were evaluated on tests of spatial memory, locomotor activity and vestibular motor well as neuropathology. Similar to our adult model, we found that juvenile rats exposed to GB exhibited deficits in vestibular motor function for

  6. Metal Ion-Catalyzed Alcoholysis as a Strategy for the High Loading Destruction of Chemical Warfare Organophosphorus Agents (United States)


    and reaction products were obtained by NMR or gas chromatography – mass spectrometry (GC-MS), and, in the case of VX, also by liquid chromatography ...Thus, at the end of the project period of performance, the adaption of two new techniques was in progress: a liquid chromatography –tandem mass...of VX Simulants by Micellar Iodoso- and Iodoxybenzoate. Langmuir 1999, 15(23), pp 8113–8118. 47. Berg, F.J.; Moss, R.A.; Yang, Y.-C.; Zhang, H

  7. Medical countermeasure against respiratory toxicity and acute lung injury following inhalation exposure to chemical warfare nerve agent VX. (United States)

    Nambiar, Madhusoodana P; Gordon, Richard K; Rezk, Peter E; Katos, Alexander M; Wajda, Nikolai A; Moran, Theodore S; Steele, Keith E; Doctor, Bhupendra P; Sciuto, Alfred M


    To develop therapeutics against lung injury and respiratory toxicity following nerve agent VX exposure, we evaluated the protective efficacy of a number of potential pulmonary therapeutics. Guinea pigs were exposed to 27.03 mg/m(3) of VX or saline using a microinstillation inhalation exposure technique for 4 min and then the toxicity was assessed. Exposure to this dose of VX resulted in a 24-h survival rate of 52%. There was a significant increase in bronchoalveolar lavage (BAL) protein, total cell number, and cell death. Surprisingly, direct pulmonary treatment with surfactant, liquivent, N-acetylcysteine, dexamethasone, or anti-sense syk oligonucleotides 2 min post-exposure did not significantly increase the survival rate of VX-exposed guinea pigs. Further blocking the nostrils, airway, and bronchioles, VX-induced viscous mucous secretions were exacerbated by these aerosolized treatments. To overcome these events, we developed a strategy to protect the animals by treatment with atropine. Atropine inhibits muscarinic stimulation and markedly reduces the copious airway secretion following nerve agent exposure. Indeed, post-exposure treatment with atropine methyl bromide, which does not cross the blood-brain barrier, resulted in 100% survival of VX-exposed animals. Bronchoalveolar lavage from VX-exposed and atropine-treated animals exhibited lower protein levels, cell number, and cell death compared to VX-exposed controls, indicating less lung injury. When pulmonary therapeutics were combined with atropine, significant protection to VX-exposure was observed. These results indicate that combinations of pulmonary therapeutics with atropine or drugs that inhibit mucous secretion are important for the treatment of respiratory toxicity and lung injury following VX exposure.

  8. Evaporation Rates of Chemical Warfare Agents Using 5-CM Wind Tunnels I. CASARM Sulfur Mustard (HD) from Glass (United States)


    CUI/6LU ui QH I- Q- s" i TO (0 ’_ r_ E u 5 i CL E (/> TJ I- Q E E en O co o o 3 C1 Q X S w w o Q. (- o < 0) s...jg O 10 •3 F P) » e o rv •* tf 0*. IN a: <•-* Pi N in <^* 8 <l V2 .-• O o C1 rj p* DA oc r- r-> - t* n -. c* >. 5 D * C" c:v- 1...N. *"*- K tO cU fVj x- t- • •>- tsg »- ,_ PJ ^ _. ,- r- ,.. •• NrNrrN(N1(\\0)(\\ nif ) c^ it o o> O E O O 9 O 9

  9. Nuclear, biological, and chemical combined injuries and countermeasures on the battlefield. (United States)

    Knudson, Gregory B; Elliott, Thomas B; Brook, Itzhak; Shoemaker, Michael O; Pastel, Ross H; Lowy, Robert J; King, Gregory L; Herzig, Thomas C; Landauer, Michael R; Wilson, Scott A; Peacock, Susan J; Bouhaouala, S Samy; Jackson, William E; Ledney, G David


    The Armed Forces Radiobiological Research Institute (AFRRI) has developed a research program to determine the major health risks from exposure to ionizing radiation in combination with biological and chemical warfare agents and to assess the extent to which exposure to ionizing radiation compromises the effectiveness of protective drugs, vaccines, and other biological and chemical warfare prophylactic and treatment strategies. AFRRI's Defense Technology Objective MD22 supports the development of treatment modalities and studies to assess the mortality rates for combined injuries from exposure to ionizing radiation and Bacillus anthracis, and research to provide data for casualty prediction models that assess the health consequences of combined exposures. In conjunction with the Defense Threat Reduction Agency, our research data are contributing to the development of casualty prediction models that estimate mortality and incapacitation in an environment of radiation exposure plus other weapons of mass destruction. Specifically, the AFFRI research program assesses the effects of ionizing radiation exposure in combination with B. anthracis, Venezuelan equine encephalomyelitis virus, Shigella sonnei, nerve agents, and mustard as well as their associated treatments and vaccines. In addition, the long-term psychological effects of radiation combined with nuclear, biological, and chemical (NBC) injuries are being evaluated. We are also assessing the effectiveness of gamma photons and high-speed neutrons and electrons for neutralizing biological and chemical warfare agents. New protocols based on our NBC bioeffects experiments will enable U.S. armed forces to accomplish military operations in NBC environments while optimizing both survival and military performance. Preserving combatants' health in an NBC environment will improve warfighting operations and mission capabilities.

  10. Hand-Held Devices Detect Explosives and Chemical Agents (United States)


    Ion Applications Inc., of West Palm Beach, Florida, partnered with Ames Research Center through Small Business Innovation Research (SBIR) agreements to develop a miniature version ion mobility spectrometer (IMS). While NASA was interested in the instrument for detecting chemicals during exploration of distant planets, moons, and comets, the company has incorporated the technology into a commercial hand-held IMS device for use by the military and other public safety organizations. Capable of detecting and identifying molecules with part-per-billion sensitivity, the technology now provides soldiers with portable explosives and chemical warfare agent detection. The device is also being adapted for detecting drugs and is employed in industrial processes such as semiconductor manufacturing.

  11. Chemical use (United States)

    US Fish and Wildlife Service, Department of the Interior — This is a summary of research and activities related to chemical use on Neal Smith National Wildlife Refuge between 1992 and 2009. The chemicals used on the Refuge...

  12. Chemical Reactors. (United States)

    Kenney, C. N.


    Describes a course, including content, reading list, and presentation on chemical reactors at Cambridge University, England. A brief comparison of chemical engineering education between the United States and England is also given. (JN)

  13. Methodology for Long-Term Permeation Test Periods for HD in High-Density Polyethylene: Universal Munitions Storage Container for the Non-Stockpile Chemical Materiel Program (United States)


    new capability in permeation cup testing. 15. SUBJECT TERMS Distilled mustard (HD) Container Thickness effect Chemical warfare agent (CWA) Fick’ room. The CWA concentration that is hazardous as a vapor leak can be quite low for eye injury and respiratory effects . The ASTM criterion...the other hand, there was considerable lag time, which is similar to a typical permeation curve. Inspecting the plot in Figure 23 reveals that the

  14. Detecting Chemical Weapons: Threats, Requirements, Solutions, and Future Challenges (United States)

    Boso, Brian


    Although chemicals have been reportedly used as weapons for thousands of years, it was not until 1915 at Ypres, France that an industrial chemical, chlorine, was used in World War I as an offensive weapon in significant quantity, causing mass casualties. From that point until today the development, detection, production and protection from chemical weapons has be an organized endeavor of many of the world's armed forces and in more recent times, non-governmental terrorist organizations. The number of Chemical Warfare Agents (CWAs) has steadily increased as research into more toxic substances continued for most of the 20 th century. Today there are over 70 substances including harassing agents like tear gas, incapacitating agents, and lethal agents like blister, blood, chocking, and nerve agents. The requirements for detecting chemical weapons vary depending on the context in which they are encountered and the concept of operation of the organization deploying the detection equipment. The US DoD, for example, has as a requirement, that US forces be able to continue their mission, even in the event of a chemical attack. This places stringent requirements on detection equipment. It must be lightweight (<2 lbs), detect a large array of chemical warfare agents and toxic industrial chemicals, detect and warn at concentration levels and time duration to prevent acute health effects, meet military ruggedness specifications and work over a wide range of temperature and humidity, and have a very high probability of detection with a similarly low probability of false positives. The current technology of choice to meet these stringent requirements is Ion Mobility Spectrometry. Many technologies are capable of detecting chemicals at the trace levels required and have been extensively developed for this application, including, but not limited to: mass spectroscopy, IR spectroscopy, RAMAN spectroscopy, MEMs micro-cantilever sensors, surface acoustic wave sensors, differential

  15. A molecularly imprinted polymer (MIP)-coated microbeam MEMS sensor for chemical detection (United States)

    Holthoff, Ellen L.; Li, Lily; Hiller, Tobias; Turner, Kimberly L.


    Recently, microcantilever-based technology has emerged as a viable sensing platform due to its many advantages such as small size, high sensitivity, and low cost. However, microcantilevers lack the inherent ability to selectively identify hazardous chemicals (e.g., explosives, chemical warfare agents). The key to overcoming this challenge is to functionalize the top surface of the microcantilever with a receptor material (e.g., a polymer coating) so that selective binding between the cantilever and analyte of interest takes place. Molecularly imprinted polymers (MIPs) can be utilized as artificial recognition elements for target chemical analytes of interest. Molecular imprinting involves arranging polymerizable functional monomers around a template molecule followed by polymerization and template removal. The selectivity for the target analyte is based on the spatial orientation of the binding site and covalent or noncovalent interactions between the functional monomer and the analyte. In this work, thin films of sol-gel-derived xerogels molecularly imprinted for TNT and dimethyl methylphosphonate (DMMP), a chemical warfare agent stimulant, have demonstrated selectivity and stability in combination with a fixed-fixed beam microelectromechanical systems (MEMS)-based gas sensor. The sensor was characterized by parametric bifurcation noise-based tracking.

  16. China’s Three Warfares Strategy Mitigates Fallout From Cyber Espionage Activities

    Directory of Open Access Journals (Sweden)

    Emilio Iasiello


    Full Text Available China is engaged in longstanding cyber espionage against the U.S., as well as other nations, to collect sensitive public and private information in support of national objectives laid out in its 12th Five Year Plan. Foreign governments citing China’s malfeasance have rebuked these activities, a claim vehemently denied by Beijing. In response, China is leveraging the “Three Warfares” an integrated three-prong information warfare strategy to combat these accusations by leveraging Media, Legal, and Psychological components designed to influence the international community. While the United States has threatened the imposition of economic sanctions, Beijing has successfully parried consequential actions by arresting U.S.-identified hackers, thereby demonstrating its commitment toward preserving a stable and peaceful cyberspace. These interrelated “Three Warfares” disciplines have targeted the cognitive processes of the U.S. leadership, as well as the international public’s perception of China as a global threat, thereby having successfully forestalled the implementation of any effective punitive or economic deterrence strategy to include the imposition of cyber sanctions.

  17. Extraordinary Measures: Drone Warfare, Securitization, and the “War on Terror”

    Directory of Open Access Journals (Sweden)

    Romaniuk Scott Nicholas


    Full Text Available The use of unmanned aerial vehicles or “drones,” as part of the United States’ (US targeted killing (TK program dramatically increased after the War on Terror (WoT was declared. With the ambiguous nature and parameters of the WoT, and stemming from the postulation of numerous low-level, niche-, and other securitizations producing a monolithic threat, US drone operations now constitute a vital stitch in the extensive fabric of US counterterrorism policy. This article employs the theories of securitization and macrosecuritization as discussed by Buzan (1991, 2006, and Buzan and Wæver (2009 to understand targeted killing, by means of weaponized drones, as an extraordinary measure according to the Copenhagen School’s interpretation. An overarching securitization and the use of the “security” label warrants the emergency action of targeted killing through the use of drones as an extraordinary measure. We argue that the WoT serves as a means of securitizing global terrorism as a threat significant enough to warrant the use of drone warfare as an extraordinary use of force. By accepting the WoT as a securitization process we can reasonably accept that the US’ response(s against that threat are also securitized and therefore become extraordinary measures.

  18. Approximation and Filtering Techniques for Navigation Data in Time-critical Electronic Warfare Systems

    Directory of Open Access Journals (Sweden)

    Vanitha D.


    Full Text Available This paper presents a holistic solution to the navigation requirements in a time critical electronic warfare systems like missile warning systems (MWS. In a passive MWS using IR sensors the efficiency of the system is determined by attributes such as low false alarm rate, minimal response time and ability to track different IR radiating objects by association and correlation of consecutive detections through time. Such a system is required to be supported by a navigation system capable of accurate estimation of the aircraft position, attitude angles and altitude. In this paper, estimation techniques used to accurately calculate aircraft navigation data at the time of capture of IR frames are discussed. The paper discusses about synchronization of INGPS, IR sensors & Processor on to same timeline. The paper also intends to evaluate the performance of wavelet transform filter in effective elimination of noise in navigation parameters like acceleration and attitude angle rates for a better estimation of position and attitude.Defence Science Journal, 2013, 63(2, pp.204-209, DOI:

  19. Healthcare and warfare. Medical space, mission and apartheid in twentieth century northern Namibia. (United States)

    Nord, Catharina


    In the year 1966, the first government hospital, Oshakati hospital, was inaugurated in northern South-West Africa. It was constructed by the apartheid regime of South Africa which was occupying the territory. Prior to this inauguration, Finnish missionaries had, for 65 years, provided healthcare to the indigenous people in a number of healthcare facilities of which Onandjokwe hospital was the most important. This article discusses these two agents' ideological standpoints. The same year, the war between the South-West African guerrillas and the South African state started, and continued up to 1988. The two hospitals became involved in the war; Oshakati hospital as a part of the South African war machinery, and Onandjokwe hospital as a 'terrorist hospital' in the eyes of the South Africans. The missionary Onandjokwe hospital was linked to the Lutheran church in South-West Africa, which became one of the main critics of the apartheid system early in the liberation war. Warfare and healthcare became intertwined with apartheid policies and aggression, materialised by healthcare provision based on strategic rationales rather than the people's healthcare needs. When the Namibian state took over a ruined healthcare system in 1990, the two hospitals were hubs in a healthcare landscape shaped by missionary ambitions, war and apartheid logic.

  20. Global physics: from percolation to terrorism, guerilla warfare and clandestine activities (United States)

    Galam, Serge


    The September 11 attack on the US has revealed an unprecedented terrorism with worldwide range of destruction. It is argued to result from the first worldwide percolation of passive supporters. They are people sympathetic to the terrorism cause but without being involved with it. They just do not oppose it in case they could. This scheme puts suppression of the percolation as the major strategic issue in the fight against terrorism. Acting on the population is shown to be useless. Instead a new strategic scheme is suggested to increase the terrorism percolation threshold and in turn suppress the percolation. The relevant associated space is identified as a multi-dimensional social space including both the ground earth surface and all various independent flags displayed by the terrorist group. Some hints are given on how to shrink the geographical spreading of terrorism threat. The model apply to a large spectrum of clandestine activities including guerilla warfare as well as tax evasion, corruption, illegal gambling, illegal prostitution and black markets.

  1. Nano-based chemical sensor array systems for uninhabited ground and airborne vehicles (United States)

    Brantley, Christina; Ruffin, Paul B.; Edwards, Eugene


    In a time when homemade explosive devices are being used against soldiers and in the homeland security environment, it is becoming increasingly evident that there is an urgent need for high-tech chemical sensor packages to be mounted aboard ground and air vehicles to aid soldiers in determining the location of explosive devices and the origin of bio-chemical warfare agents associated with terrorist activities from a safe distance. Current technologies utilize relatively large handheld detection systems that are housed on sizeable robotic vehicles. Research and development efforts are underway at the Army Aviation & Missile Research, Development, and Engineering Center (AMRDEC) to develop novel and less expensive nano-based chemical sensors for detecting explosives and chemical agents used against the soldier. More specifically, an array of chemical sensors integrated with an electronics control module on a flexible substrate that can conform to and be surface-mounted to manned or unmanned vehicles to detect harmful species from bio-chemical warfare and other explosive devices is being developed. The sensor system under development is a voltammetry-based sensor system capable of aiding in the detection of any chemical agent and in the optimization of sensor microarray geometry to provide nonlinear Fourier algorithms to characterize target area background (e.g., footprint areas). The status of the research project is reviewed in this paper. Critical technical challenges associated with achieving system cost, size, and performance requirements are discussed. The results obtained from field tests using an unmanned remote controlled vehicle that houses a CO2/chemical sensor, which detects harmful chemical agents and wirelessly transmits warning signals back to the warfighter, are presented. Finally, the technical barriers associated with employing the sensor array system aboard small air vehicles will be discussed.

  2. 竞技排球运动心理战理论模型的构建%Theoretical Models of Psychological Warfare Built in Competitive Volleyball

    Institute of Scientific and Technical Information of China (English)



    通过对军事心理学中心理战思想的精心研读,结合竞技排球运动与战场心理战的共通之处,从理论建设、专业人才建设、规章制度建设、谋略创新建设以及球队心理素质建设五个方面构建了竞技排球运动心理战的理论模型。%This article through the study of thoughts of psychological warfare in military psychology carefully, combined with the commons of volleyball and psychological warfare, from five aspects that construction of theory, construction of professional, and construction of rules and regulations, construction of counsel innovation and construction of team psychological quality to construct the theoretical model of psychological warfare of volleyball.

  3. The Effect of the Goldwater-Nichols Department of Defense Reorganization Act on Surface Warfare Officer Career Paths. (United States)


    OF THE GOLDWATER-NIaIS DEARnhmr OF DESE REOFGANIZATION ACr ON SURFACE WARFARE OFFICER CAREER PATHS 12. PERSONAL AUTHOR(S) Steward, Thomas F. these levels. The stocks at tour 12D increase 160o by the 5 %i year of the simulation. This is depicted graphically in Figure -4.2. The stocks of...with Datj B.,e Management ,DB.MI and graphics software to provide a powerful decisIon sUpporT " for the manpower analyst. e.r5 dt r APPENDIX A FLOW

  4. Measurement of 100 B. anthracis Ames spores within 15 minutes by SERS at the US Army Edgewood Chemical Biological Ctr. (United States)

    Farquharson, Stuart; Shende, Chetan; Smith, Wayne; Huang, Hermes; Sperry, Jay; Sickler, Todd; Prugh, Amber; Guicheteau, Jason


    Since the distribution of Bacillus anthracis-Ames spores through the US Postal System, there has been a persistent fear that biological warfare agents will be used by terrorists against our military abroad and our civilians at home. While there has been substantial effort since the anthrax attack of 2001 to develop analyzers to detect this and other biological warfare agents, the analyzers remain either too slow, lack sensitivity, produce high false-positive rates, or cannot be fielded. In an effort to overcome these limitations we have been developing a surface-enhanced Raman spectroscopy system. Here we describe the use of silver nanoparticles functionalized with a short peptide to selectively capture Bacillus anthracis spores and produce SER scattering. Specifically, measurements of 100 B. anthracis-Ames spores/mL in ~25 minutes performed at the US Army's Edgewood Chemical Biological Center are presented. The measurements provide a basis for the development of systems that can detect spores collected from the air or water supplies with the potential of saving lives during a biological warfare attack.

  5. Chemical sensors (United States)

    Lowell, J.R. Jr.; Edlund, D.J.; Friesen, D.T.; Rayfield, G.W.


    Sensors responsive to small changes in the concentration of chemical species are disclosed. The sensors comprise a mechanochemically responsive polymeric film capable of expansion or contraction in response to a change in its chemical environment. They are operatively coupled to a transducer capable of directly converting the expansion or contraction to a measurable electrical response. 9 figures.

  6. Surface plasmon resonance detection of biological warfare agent Staphylococcal enterotoxin B using high affinity monoclonal antibody

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Garima; Singh, Pawan K.; Boopathi, M., E-mail:; Kamboj, D.V.; Singh, Beer; Vijayaraghavan, R.


    A novel sensitive method was developed for the detection as well as quantification of Staphylococcal enterotoxin B (SEB) using surface plasmon resonance (SPR). It is well known that the amount of SEB needed to cause the intoxication to human beings is very less and this concentration (0.02 {mu}g/kg) is highly dangerous, hence, it is used as biological warfare agent. Thus, the need to develop a reliable and potential detection system against SEB is warranted. In the present work, SEB antibody was immobilized on carboxymethyldextran modified gold chip. The immobilization of SEB antibody and interaction of antigen with immobilized antibody were in-situ characterized by SPR and electrochemical impedance spectroscopy. A sample solution containing SEB antigen was injected in a working channel and the results revealed linearity in the concentration from 2.0 to 32.0 pM with a detection limit of 1.0 pM. By using kinetic evaluation software, K{sub D} (equilibrium constant) and Bmax (maximum binding capacity of analyte) values were calculated and found to be 13 pM and 424.23, respectively. Moreover, the thermodynamic parameter, change in Gibb's free energy was deduced and found to be -62.08 kJ/mol and this value shows the spontaneous interaction between SEB antigen and SEB antibody. In order to optimize the detection method, temperature and pH variation studies were also performed. Interference study was conducted to know the selectivity for the antigen-antibody interaction of SEB. The selectivity efficiency of SEB, SEC, SEA and SED were 100, 27.15, 20.01 and 12.05%, respectively towards SEB antibody.

  7. Chemical intolerance

    DEFF Research Database (Denmark)

    Dantoft, Thomas Meinertz; Andersson, Linus; Nordin, Steven;


    Chemical intolerance (CI) is a term used to describe a condition in which the sufferer experiences a complex array of recurrent unspecific symptoms attributed to low-level chemical exposure that most people regard as unproblematic. Severe CI constitutes the distinguishing feature of multiple...... chemical sensitivity (MCS). The symptoms reported by CI subjects are manifold, involving symptoms from multiple organs systems. In severe cases of CI, the condition can cause considerable life-style limitations with severe social, occupational and economic consequences. As no diagnostic tools for CI...

  8. Hazardous Chemicals

    Centers for Disease Control (CDC) Podcasts


    Chemicals are a part of our daily lives, providing many products and modern conveniences. With more than three decades of experience, The Centers for Disease Control and Prevention (CDC) has been in the forefront of efforts to protect and assess people's exposure to environmental and hazardous chemicals. This report provides information about hazardous chemicals and useful tips on how to protect you and your family from harmful exposure.  Created: 4/10/2007 by CDC National Center for Environmental Health.   Date Released: 4/13/2007.

  9. The Department of Defense Commitment to the Destruction and Remediation of Non-Stockpile Chemical Materiel: Can Present Policy and Approaches Effectively Meet the Challenges to Eliminate the Threat to the Public? (United States)


    the destruction of Recovered Chemical Warfare Material. Current projections are that 42 states are impacted by the possible presence of RCWM...the Army. LUCs can impact property values and flexibility for various uses, many communities want remedies that require no restrictions on land use...Huntsville, Al: Headquarters 4 th District USACOE, January 2002. Department of the Army, Army Environmental Command. Army Enviromental Cleanup

  10. Silicon chip integrated photonic sensors for biological and chemical sensing (United States)

    Chakravarty, Swapnajit; Zou, Yi; Yan, Hai; Tang, Naimei; Chen, Ray T.


    We experimentally demonstrate applications of photonic crystal waveguide based devices for on-chip optical absorption spectroscopy for the detection of chemical warfare simulant, triethylphosphate as well as applications with photonic crystal microcavity devices in the detection of biomarkers for pancreatic cancer in patient serum and cadmium metal ions in heavy metal pollution sensing. At mid-infrared wavelengths, we experimentally demonstrate the higher sensitivity of photonic crystal based structures compared to other nanophotonic devices such as strip and slot waveguides with detection down to 10ppm triethylphosphate. We also detected 5ppb (parts per billion) of cadmium metal ions in water at near-infrared wavelengths using established techniques for the detection of specific probe-target biomarker conjugation chemistries.

  11. Mechanism of injury and microbiological flora of the geographical location are essential for the prognosis in soldiers with serious warfare injuries

    DEFF Research Database (Denmark)

    Wetterslev, Mik; Rose-Larsen, Katrine; Hansen-Schwartz, Jacob


    has been and remains a substantial part of warfare, and this review has showed us that the knowledge of the mechanism of injury is indeed essential, and that intelligence on the microbiological flora of the geographical location of the conflict is essential. FUNDING: not relevant. TRIAL REGISTRATION...

  12. Surface desorption atmospheric pressure chemical ionization mass spectrometry for direct ambient sample analysis without toxic chemical contamination. (United States)

    Chen, Huanwen; Zheng, Jian; Zhang, Xie; Luo, Mingbiao; Wang, Zhichang; Qiao, Xiaolin


    Ambient mass spectrometry, pioneered with desorption electrospray ionization (DESI) technique, is of increasing interest in recent years. In this study, a corona discharge ionization source is adapted for direct surface desorption chemical ionization of compounds on various surfaces at atmospheric pressure. Ambient air, with about 60% relative humidity, is used as a reagent to generate primary ions such as H(3)O(+), which is then directed to impact the sample surface for desorption and ionization. Under experimental conditions, protonated or deprotonated molecules of analytes present on various samples are observed using positive or negative corona discharge. Fast detection of trace amounts of analytes present in pharmaceutical preparations, viz foods, skins and clothes has been demonstrated without any sample pretreatment. Taking the advantage of the gasless setup, powder samples such as amino acids and mixtures of pharmaceutical preparations are rapidly analyzed. Impurities such as sudan dyes in tomato sauce are detected semiquantitatively. Molecular markers (e.g. putrescine) for meat spoilage are successfully identified from an artificially spoiled fish sample. Chemical warfare agent stimulants, explosives and herbicides are directly detected from the skin samples and clothing exposed to these compounds. This provides a detection limit of sub-pg (S/N > or = 3) range in MS2. Metabolites and consumed chemicals such as glucose are detected successfully from human skins. Conclusively, surface desorption atmospheric pressure chemical ionization (DAPCI) mass spectrometry, without toxic chemical contamination, detects various compounds in complex matrices, showing promising applications for analyses of human related samples.

  13. Compilation of existing chemical agent guidelines table as of September 1997

    Energy Technology Data Exchange (ETDEWEB)

    Foust, C.B.


    Public Law 99-145 requires the US Department of the Army to dispose of the lethal chemical agents and munitions stockpile stored at eight Army installations throughout the continental US and Johnston Atoll in the Pacific. Recognition by the US Army that a potential threat to the public from continued storage was greater than the threat from transportation and demilitarization of chemical agents gave rise to the Chemical Stockpile Emergency Preparedness Program (CSEPP). CSEPP is a community emergency preparedness program complementing the Department of Defense`s initiative to destroy domestic stockpiles of aged chemical warfare agent munitions. The Federal Emergency Management Agency (FEMA) and the US Army jointly coordinate and direct the CSEPP. The Compilation of Existing Chemical Agent Guidelines Table was developed under the direction of FEMA and the US Army Center for Health Promotion and Preventive Medicine (USACHPPM). The purpose of this Table is to identify established chemical warfare agent guidelines, standards, and interim standards as of September 1997, and place them in an explanatory context for ready use by the CSEPP community. This Table summarizes and organizes information from numerous agencies and review bodies responsible for recommending exposure guidelines [e.g., The Centers for Disease Control and Prevention (CDC), Committee on Toxicology (COT), Environmental Protection Agency (EPA), FEMA, Army and other federal agencies]. This Table provides references for the interested reader, but does not provide data and assumptions on which exposure guidelines were based, or comment on the rationale or appropriateness of the given values. To do so is beyond the scope of work for this task.

  14. Environmental genotoxicity assessment along the transport routes of chemical munitions leading to the dumping areas in the Baltic Sea. (United States)

    Baršienė, Janina; Butrimavičienė, Laura; Grygiel, Włodzimierz; Stunžėnas, Virmantas; Valskienė, Roberta; Greiciūnaitė, Janina; Stankevičiūtė, Milda


    The frequencies of micronuclei (MN), nuclear buds (NB) and nuclear buds on filament (NBf) were examined in 660 specimens of herring (Clupea harengus) collected in 2009-2014 at 65 study stations located mainly along the chemical munition transport routes in the Baltic Sea. The frequency of nuclear abnormalities was strongly increased in herring caught at four stations located close to chemical munition dumping sites, or CWAs - substances (chemical warfare agents) in sediments. Significant increase of MN, NB and NBf was observed in fish caught November 2010-2013 compared to 2009. The most significantly increased genotoxicity responses were recorded in fish caught at stations along CW (chemical weapons) transport routes, close to the Bornholm CW dumping area, in zones with CWAs in sediments and with oil-gas platforms.

  15. Chemical and biological weapons in the 'new wars'. (United States)

    Ilchmann, Kai; Revill, James


    The strategic use of disease and poison in warfare has been subject to a longstanding and cross-cultural taboo that condemns the hostile exploitation of poisons and disease as the act of a pariah. In short, biological and chemical weapons are simply not fair game. The normative opprobrium is, however, not fixed, but context dependent and, as a social phenomenon, remains subject to erosion by social (or more specifically, antisocial) actors. The cross cultural understanding that fighting with poisons and disease is reprehensible, that they are taboo, is codified through a web of interconnected measures, principal amongst these are the 1925 Geneva Protocol; the Biological Weapons Convention; and the Chemical Weapons Convention. Whilst these treaties have weathered the storm of international events reasonably well, their continued health is premised on their being 'tended to' in the face of contextual changes, particularly facing changes in science and technology, as well as the changed nature and character of conflict. This article looks at the potential for normative erosion of the norm against chemical and biological weapons in the face of these contextual changes and the creeping legitimization of chemical and biological weapons.

  16. Chemical Mahjong (United States)

    Cossairt, Travis J.; Grubbs, W. Tandy


    An open-access, Web-based mnemonic game is described whereby introductory chemistry knowledge is tested using mahjong solitaire game play. Several tile sets and board layouts are included that are themed upon different chemical topics. Introductory tile sets can be selected that prompt the player to match element names to symbols and metric…

  17. Chemical dispersants

    NARCIS (Netherlands)

    Rahsepar, Shokouhalsadat; Smit, Martijn P.J.; Murk, Albertinka J.; Rijnaarts, Huub H.M.; Langenhoff, Alette A.M.


    Chemical dispersants were used in response to the Deepwater Horizon oil spill in the Gulf of Mexico, both at the sea surface and the wellhead. Their effect on oil biodegradation is unclear, as studies showed both inhibition and enhancement. This study addresses the effect of Corexit on oil biodeg

  18. Biological warfare warriors, secrecy and pure science in the Cold War: how to understand dialogue and the classifications of science. (United States)

    Bud, Robert


    This paper uses a case study from the Cold War to reflect on the meaning at the time of the term 'Pure Science'. In 1961, four senior scientists from Britain's biological warfare centre at Porton Down visited Moscow both attending an International Congress and visiting Russian microbiological and biochemical laboratories. The reports of the British scientists in talking about a limited range of topics encountered in the Soviet Union expressed qualities of openness, sociologists of the time associated with pure science. The paper reflects on the discourses of "Pure Science", secrecy and security in the Cold War. Using Bakhtin's approach, I suggest the cordial communication between scientists from opposing sides can be seen in terms of the performance, or speaking, of one language among several at their disposal. Pure science was the language they were allowed to share outside their institutions, and indeed political blocs.

  19. Capillary zone electrophoresis analysis and detection of mid-spectrum biological warfare agents. Suffield memorandum No. 1463

    Energy Technology Data Exchange (ETDEWEB)

    Boulet, C.A.


    Mid-spectrum biological warfare agents such as proteins, peptides, and toxins are often difficult to analyze and often require individually developed assay methods for detection and identification. In this regard, capillary electrophoresis is an important, emerging technique for separation and quantitation of peptides and proteins, providing separation efficiencies up to two orders of magnitude greater than high performance liquid chromatography. The technique can also analyze a broad range of compounds, has a simple instrument design which can be automated, and has low sample volume requirements. In this study, a highly efficient and reproducible capillary zone electrophoresis method was developed to separate and identify a series of nine peptides of defense interest including bradykinin, leucine enkephalin, and oxytocin. The paper demonstrates three strategies which could be used in a fully automated field detection and identification system for unknown peptides.

  20. 网络电磁空间作战威胁分析%Analysis of Cyber Electromagnetic Space Warfare Threat

    Institute of Scientific and Technical Information of China (English)



    提出了网电空间作战几个需要关注的问题以及解决方案,使得部队可以根据战场具体环境,进行适应性的应用。首先陈述了网电空间作战的特点,接着阐述了在网电空间中军队所要面临、应对的现实威胁。然后针对这些威胁进行了进一步分析,并且确定了战场环境下所需要的基础安全条件。最后从四个层面阐述了网电空间的脆弱性,同时给出了防御措施。该工作可以对确立可实施的网电空间战术以及有效地组织网电空间行动形成支撑。%A cyber warfare scenario is shown ,which is applicable on the basis of modern battlefield situations .The sce-nario removes misconceptions about present cyber warfare properties and defines actual dangers that should be prepared for in the background of the cyberspace .The dangers are analyzed further and the basic security prerequisites are determined . Technologies are proposed that offer the basic necessary for achieving these prerequisites .An organization of cyberspace weaknesses and the correlative defenses in four levels is shown .Conclusions are drawn that demonstrate the manner in which cyber threats should be determined ,their likelihood assessed and averted .This knowledge leads to the determination of im-plementable cyber tactics and effective organization of cyber operations .


    Directory of Open Access Journals (Sweden)

    Giuseppe CAFORIO


    Full Text Available This article deals with the problems of anxiety, stress and psychological discomfort that can affect soldiers sent on asymmetric warfare operations. It is based on secondary analysis of the data of two important field researches whose results have recently (2013 been published. Although the two researches adopted different methodologies, the testimonies are fully comparable and show that soldiers from different countries and cultures display common or similar reactions when they are placed in the stress conditions that the asymmetric environment involves. The approach of the paper is drawn up in such a way as to make the reader a participating observer of the reality of such missions. It is therefore centered on the personal testimonies of the soldiers interviewed in the two researches, testimonies reported just as they are, in their simplicity and, often, drama, with comments by the author kept to a minimum in order to give readers ample opportunity to evaluate and interpret the reported texts on their own. The research data, drawn from the declarations of those directly concerned, reveal the existence of a problem of psychological distress resulting from deployment in asymmetric warfare situations that is in part different in the causes of the problems resulting from deployment in traditional combat and affects percentages of participating soldiers that are not high but definitely significant. The highest incidence appears to be constituted by problems relating to reintegration into normal social and working life upon returning from the mission. This is followed in percentage terms by anxiety situations relating to life far from the family, due in large part to a sense of powerlessness for the scant possibility of managing family situations that may have cropped up or already existed beforehand.

  2. On-matrix derivatization extraction of chemical weapons convention relevant alcohols from soil. (United States)

    Chinthakindi, Sridhar; Purohit, Ajay; Singh, Varoon; Dubey, D K; Pardasani, Deepak


    Present study deals with the on-matrix derivatization-extraction of aminoalcohols and thiodiglycols, which are important precursors and/or degradation products of VX analogues and vesicants class of chemical warfare agents (CWAs). The method involved hexamethyldisilazane (HMDS) mediated in situ silylation of analytes on the soil. Subsequent extraction and gas chromatography-mass spectrometry analysis of derivatized analytes offered better recoveries in comparison to the procedure recommended by the Organization for the Prohibition of Chemical Weapons (OPCW). Various experimental conditions such as extraction solvent, reagent and catalyst amount, reaction time and temperature were optimized. Best recoveries of analytes ranging from 45% to 103% were obtained with DCM solvent containing 5%, v/v HMDS and 0.01%, w/v iodine as catalyst. The limits of detection (LOD) and limit of quantification (LOQ) with selected analytes ranged from 8 to 277 and 21 to 665ngmL(-1), respectively, in selected ion monitoring mode.

  3. Chemical carcinogenesis

    Directory of Open Access Journals (Sweden)

    Paula A. Oliveira


    Full Text Available The use of chemical compounds benefits society in a number of ways. Pesticides, for instance, enable foodstuffs to be produced in sufficient quantities to satisfy the needs of millions of people, a condition that has led to an increase in levels of life expectancy. Yet, at times, these benefits are offset by certain disadvantages, notably the toxic side effects of the chemical compounds used. Exposure to these compounds can have varying effects, ranging from instant death to a gradual process of chemical carcinogenesis. There are three stages involved in chemical carcinogenesis. These are defined as initiation, promotion and progression. Each of these stages is characterised by morphological and biochemical modifications and result from genetic and/or epigenetic alterations. These genetic modifications include: mutations in genes that control cell proliferation, cell death and DNA repair - i.e. mutations in proto-oncogenes and tumour suppressing genes. The epigenetic factors, also considered as being non-genetic in character, can also contribute to carcinogenesis via epigenetic mechanisms which silence gene expression. The control of responses to carcinogenesis through the application of several chemical, biochemical and biological techniques facilitates the identification of those basic mechanisms involved in neoplasic development. Experimental assays with laboratory animals, epidemiological studies and quick tests enable the identification of carcinogenic compounds, the dissection of many aspects of carcinogenesis, and the establishment of effective strategies to prevent the cancer which results from exposure to chemicals.A sociedade obtém numerosos benefícios da utilização de compostos químicos. A aplicação dos pesticidas, por exemplo, permitiu obter alimento em quantidade suficiente para satisfazer as necessidades alimentares de milhões de pessoas, condição relacionada com o aumento da esperança de vida. Os benefícios estão, por

  4. Chemical cosmology

    CERN Document Server

    Boeyens, Jan CA


    The composition of the most remote objects brought into view by the Hubble telescope can no longer be reconciled with the nucleogenesis of standard cosmology and the alternative explanation, in terms of the LAMBDA-Cold-Dark-Matter model, has no recognizable chemical basis. A more rational scheme, based on the chemistry and periodicity of atomic matter, opens up an exciting new interpretation of the cosmos in terms of projective geometry and general relativity. The response of atomic structure to environmental pressure predicts non-Doppler cosmical redshifts and equilibrium nucleogenesis by alp

  5. Introduction: Envisioning Future War; Strategic Insights, v. 10, Special issue (October 2011), 1-6. Topic: Global Trends and Future Warfare


    Moran, Daniel


    This article appeared in Strategic Insights, v.10, Special issue (October 2011), 1-6. Topic: Global Trends and Future Warfare Approved for public display, distribution unlimited The workshop whose proceedings are presented here was convened to provide the National Intelligence Council (NIC) with insight into the way war in the intermediate future, meaning the next twenty years or so, is viewed from the perspective of America's allies, partners, and potential adversaries. The group took ...

  6. Acoustic Warfare of Submarine and Its Development Tendency%潜艇水声对抗及其发展趋势

    Institute of Scientific and Technical Information of China (English)

    李峰; 单广超; 李晖


    The acoustic warfare of submarine,that can effectively improve the ability to survive in the com-bat of submarine,is the main content of submarine active defense operations.With the development of an-ti-sub equipment and technology,the acoustic countermeasure equipment will truly have the ability of un-derwater acoustic warfare.The paper analyses the type of modern acoustic warfare operation and mainly studies the type of the acoustic countermeasure equipment of operation in the future.%潜艇水声对抗是潜艇积极防御作战的主要内容,实施水声对抗能够有效提高潜艇在作战中的生存能力。根据反潜装备和技术的发展,分析了现代潜艇水声对抗作战样式,并重点对未来潜艇水声对抗装备作战样式的发展趋势进行了研究。

  7. 大数据在现代战争中的价值探析%Research on the Big Data’s Value in Modern Warfare

    Institute of Scientific and Technical Information of China (English)



    Modern warfare is information-dominated. Information penetrates the all aspects of the warfare and becomes one of the key factors which influence the success of the warfare. Effective acquisition, storage, processing and distribution of military in-formation via big data technology can promote the ability of intelligence acquisition and command decision-making, handle the choke point of information flow, advance the integration of operational system, and strengthen the information security and pro-tection.%现代战争是“信息主导”的战争,信息渗透到战争的方方面面,成为影响战争胜负的重要因素之一,利用大数据技术对军事信息进行高效获取、存储、处理和分发,能够有效提升情报获取、指挥决策能力,疏通信息流瓶颈,推进作战体系融合,增强信息安全防护能力。

  8. Chemical Analyses (United States)

    Bulluck, J. W.; Rushing, R. A.


    As a preliminary study on the effects of chemical aging of polymer materials MERL and TRI have examined two polymeric materials that are typically used for offshore umbilical applications. These two materials were Tefzel, a copolymer of ethylene and tetrafluoroethylene, and Coflon, polyvinylidene fluoride. The Coflon specimens were cut from pipe sections and exposed to H2S at various temperatures and pressures. One of these specimens was tested for methane permeation, and another for H2S permeation. The Tefzel specimens were cut from .05 mm sheet stock material and were exposed to methanol at elevated temperature and pressure. One of these specimens was exposed to methanol permeation for 2 days at 100 C and 2500 psi. An additional specimen was exposed to liquid methanol for 3 days at 150 C and 15 Bar. Virgin specimens of each material were similarly prepared and tested.

  9. Interpretation of a New Found Japanese Biological Warfare File%对一份新发现日本细菌战档案的解读

    Institute of Scientific and Technical Information of China (English)



    Unit 731 focused on the research of Biological Warfare theory in the plan of biological warfare , But be-cause? of lack of evidence chain , this research is relatively backward .Entry Hojo who was the core member of Unit 731 , his speech draft On Biological Warfareis the recently found materials and evidences , has great academic research value.Through the interpretation of the Biological Warfare , analyzing the biological warfare is the vital criterion to e-valuate the research level and research competence , which is also an effective supplement to the evidences for the Jap-anese biological warfare war of aggression against China .%七三一部队在细菌战谋划中注重对细菌战理论的研究,但囿于相关证据链的缺失,致使此项研究相对滞后。七三一部队核心成员北条圆了的演讲稿《关于细菌战》作为新资料、新证据,具有重大的学术研究价值,是对国内所藏相关资料的重要补充,有助于丰富学术界对于日本细菌战理论问题的认知。《关于细菌战》是北条圆了在长期实践基础上积累形成的细菌战理论,可以在一定程度上还原战时日本细菌战的研究情况。通过对北条圆了其人及《关于细菌战》的梳理和解读,进而剖析日本细菌战理论是评估二战时期日本细菌战研究水平和研究能力的重要尺度,也是对日本侵华细菌战证据链的有效补充。

  10. Warfare and Socio-political hierarchies: reflections on non-State societies of the predynastic Nile Valley

    Directory of Open Access Journals (Sweden)

    Gayubas, Augusto


    Full Text Available In a recent article, anthropologist Robert L. Carneiro reassessed his most debated hypothesis about the emergence of chiefdoms and the State as a result of environmental or social circumscription, theorized for a series of historical contexts including that of the Predynastic Nile Valley. The problem of the origin of the State is beyond our scope, but regarding the emergence of institutionalized leadership and chiefdoms in the Nile Valley, Carneiro’s ideas about warfare as a main factor in the process of social change remain interesting, even when his insistence in circumscription is still debatable. The aim of the present paper is to briefly review the available archaeological evidence of warfare among non-State societies of the Predynastic Nile Valley, and to evaluate its possible relation to the emergence of socio-political hierarchies, in turn refering to and criticizing some of Carneiro’s recent ideas about the issue.En un artículo reciente, Robert L. Carneiro presentó una reconsideración de su muy debatida hipótesis acerca de la emergencia de sociedades de jefatura y del Estado como resultado de un contexto de circunscripción ambiental, teorizada para una serie de situaciones históricas, entre ellas el valle del Nilo predinástico. El problema del origen del Estado excede las posibilidades de este trabajo, pero en lo que respecta al surgimiento de jefaturas, consideramos que las ideas de Carneiro acerca de la guerra como factor de importancia en el proceso revisten cierto interés, aun cuando su insistencia en la circunscripción continúa siendo discutible. El objetivo del presente artículo es considerar la evidencia arqueológica de guerra disponible para las sociedades no estatales del valle del Nilo predinástico y evaluar la posible relación entre dichos testimonios y la emergencia de jerarquías sociopolíticas, refiriendo y criticando algunas de las ideas recientes de Carneiro sobre el problema.


    Energy Technology Data Exchange (ETDEWEB)

    Calvin, Melvin


    How did life come to be on the surface of the earth? Darwin himself recognized that his basic idea of evolution by variation and natural selection must be a continuous process extending backward in time through that period in which the first living things arose and into the period of 'Chemical Evolution' which preceded it. We are approaching the examination of these events by two routes. One is to seek for evidence in the ancient rocks of the earth which were laid down prior to that time in which organisms capable of leaving their skeletons in the rocks to be fossilized were in existence. This period is sometime prior to approximately 600 million years ago. The earth is believed to have taken its present form approximately 4700 million years ago. We have found in rocks whose age is about 1000 million years certain organic molecules which are closely related to the green pigment of plants, chlorophyll. This seems to establish that green plants were already fluorishing prior to that time. We have now found in rocks of still greater age, namely, 2500 million years, the same kinds of molecules mentioned above which can be attributed to the presence of living organisms. If these molecules are as old as the rocks, we have thus shortened the time available for the generation of the complex biosynthetic sequences which give rise to these specific hydrocarbons (polyisoprenoids) to less than 2000 million years.

  12. Chemical information science coverage in Chemical Abstracts. (United States)

    Wiggins, G


    For many years Chemical Abstracts has included in its coverage publications on chemical documentation or chemical information science. Although the bulk of those publications can be found in section 20 of Chemical Abstracts, many relevant articles were found scattered among 39 other sections of CA in 1984-1985. In addition to the scattering of references in CA, the comprehensiveness of Chemical Abstracts as a secondary source for chemical information science is called into question. Data are provided on the journals that contributed the most references on chemical information science and on the languages of publication of relevant articles.

  13. Nature's chemicals and synthetic chemicals: comparative toxicology.


    Ames, B N; Profet, M; Gold, L S


    The toxicology of synthetic chemicals is compared to that of natural chemicals, which represent the vast bulk of the chemicals to which humans are exposed. It is argued that animals have a broad array of inducible general defenses to combat the changing array of toxic chemicals in plant food (nature's pesticides) and that these defenses are effective against both natural and synthetic toxins. Synthetic toxins such as dioxin are compared to natural chemicals, such as indole carbinol (in brocco...

  14. Hydrogeologic and water-quality data for the explosive experimental area, Naval Surface Warfare Center, Dahlgren Site, Dahlgren, Virginia (United States)

    Hammond, E.C.; Bell, C.F.


    Hydrogeologic and water-quality data were collected at the Explosive Experimental Area, Naval Surface Warfare Center, Dahlgren Site at Dahlgren, Virginia, as part of a hydrogeologic assessment of the shallow aquifer system begun in 1993. The U.S. Geological Survey conducted this study to provide the U.S. Navy with hydrogeologic data to aid in the evaluation of the effects from remediation of contaminated sites and to protect against additional contamination. This report describes the ground-water observation- well network, hydrogeologic, and water-quality data collected between October 1993 and April 1995. The report includes a description of the locations and construction of 28 observation wells on the Explosive Experimental Area. Hydrogeologic data include lithologic logs, geophysical logs, and vertical hydraulic conductivity measurements of selected core intervals. Hydrologic data include synoptic and hourly measurements of ground-water levels, and observation-well slug tests to determine horizontal hydraulic conductivity. Water-quality data include analyses of major dissolved constituents in ground water and surface water.

  15. Extraordinary Adaptive Plasticity of Colorado Potato Beetle: “Ten-Striped Spearman” in the Era of Biotechnological Warfare

    Directory of Open Access Journals (Sweden)

    Aleksandar Cingel


    Full Text Available Expanding from remote areas of Mexico to a worldwide scale, the ten-striped insect, the Colorado potato beetle (CPB, Leptinotarsa decemlineata Say, has risen from being an innocuous beetle to a prominent global pest. A diverse life cycle, phenotypic plasticity, adaptation to adverse conditions, and capability to detoxify or tolerate toxins make this insect appear to be virtually “indestructible”. With increasing advances in molecular biology, tools of biotechnological warfare were deployed to combat CPB. In the last three decades, genetically modified potato has created a new challenge for the beetle. After reviewing hundreds of scientific papers dealing with CPB control, it became clear that even biotechnological means of control, if used alone, would not defeat the Colorado potato beetle. This control measure once again appears to be provoking the potato beetle to exhibit its remarkable adaptability. Nonetheless, the potential for adaptation to these techniques has increased our knowledge of this pest and thus opened possibilities for devising more sustainable CPB management programs.

  16. From energy-rich phosphate compounds to warfare agents: A review on the chemistry of organic phosphate compounds

    Directory of Open Access Journals (Sweden)

    Luciano Albino Giusti


    Full Text Available The chemistry of the phosphorus-oxygen bond is widely used in biological systems in many processes, such as energy transduction and the storage, transmission and expression of genetic information, which are essential to living beings in relation to a wide variety of functions. Compounds containing this bond have been designed for many purposes, ranging from agricultural defense systems, in order to increase food production, to nerve agents, for complaining use in warfare. In this review, features related to the chemistry of organic phosphate compounds are discussed, with particular emphasis on the role of phosphate compounds in biochemical events and in nerve agents. To this aim, the energy-rich phosphate compounds are focused, particularly the mode of their use as energy currency in cells. Historical and recent studies carried out by research groups have tried to elucidate the mechanism of action of enzymes responsible for energy transduction through the use of biochemical studies, enzyme models, and artificial enzymes. Finally, recent studies on the detoxification of nerve agents based on phosphorous esters are presented, and on the utilization of chromogenic and fluorogenic chemosensors for the detection of these phosphate species.

  17. Computational Enzymology and Organophosphorus Degrading Enzymes: Promising Approaches Toward Remediation Technologies of Warfare Agents and Pesticides. (United States)

    Ramalho, Teodorico C; de Castro, Alexandre A; Silva, Daniela R; Silva, Maria Cristina; Franca, Tanos C C; Bennion, Brian J; Kuca, Kamil


    The re-emergence of chemical weapons as a global threat in hands of terrorist groups, together with an increasing number of pesticides intoxications and environmental contaminations worldwide, has called the attention of the scientific community for the need of improvement in the technologies for detoxification of organophosphorus (OP) compounds. A compelling strategy is the use of bioremediation by enzymes that are able to hydrolyze these molecules to harmless chemical species. Several enzymes have been studied and engineered for this purpose. However, their mechanisms of action are not well understood. Theoretical investigations may help elucidate important aspects of these mechanisms and help in the development of more efficient bio-remediators. In this review, we point out the major contributions of computational methodologies applied to enzyme based detoxification of OPs. Furthermore, we highlight the use of PTE, PON, DFP, and BuChE as enzymes used in OP detoxification process and how computational tools such as molecular docking, molecular dynamics simulations and combined quantum mechanical/molecular mechanics have and will continue to contribute to this very important area of research.

  18. Reality theory: A means to control the public`s fear of chemical weapons use. Research report

    Energy Technology Data Exchange (ETDEWEB)

    Pate, B.E.


    On 20 March 1995 terrorists released the chemical nerve agent sarin into the Tokyo subway system, killing 10 commuters and changing the public`s attitude about the most basic aspect of their lives: the air they breathe and the daily ritual of their commute to work. This is the new threat the United States must face: terrorism and its attack on the will of the people forcing governments to yield to the terrorists` position. Yet there is a different public response in warfare compared with a peacetime terrorist attack. This paper examines the psychological response of people in wartime and applies this description to chemical weapons use in war and in peace. The public`s response can be predicted if one uses reality theory, a concept leaders can use to mitigate responses that would prevent the execution of national strategy.

  19. MOFabric: Electrospun Nanofiber Mats from PVDF/UiO-66-NH2 for Chemical Protection and Decontamination. (United States)

    Lu, Annie Xi; McEntee, Monica; Browe, Matthew A; Hall, Morgan G; DeCoste, Jared B; Peterson, Gregory W


    Textiles capable of capture and detoxification of toxic chemicals, such as chemical-warfare agents (CWAs), are of high interest. Some metal-organic frameworks (MOFs) exhibit superior reactivity toward CWAs. However, it remains a challenge to integrate powder MOFs into engineered materials like textiles, while retaining functionalities like crystallinity, adsorptivity, and reactivity. Here, we present a simple method of electrospinning UiO-66-NH2, a zirconium MOF, with polyvinylidene fluoride (PVDF). The electrospun composite, which we refer to as "MOFabric", exhibits comparable crystal patterns, surface area, chlorine uptake, and simulant hydrolysis to powder UiO-66-NH2. The MOFabric is also capable of breaking down GD (O-pinacolyl methylphosphonofluoridae) faster than powder UiO-66-NH2. Half-life of GD monitored by solid-state NMR for MOFabric is 131 min versus 315 min on powder UiO-66-NH2.

  20. Ion chemistry of VX surrogates and ion energetics properties of VX: new suggestions for VX chemical ionization mass spectrometry detection. (United States)

    Midey, Anthony J; Miller, Thomas M; Viggiano, A A; Bera, Narayan C; Maeda, Satoshi; Morokuma, Keiji


    Room temperature rate constants and product ion branching ratios have been measured for the reactions of numerous positive and negative ions with VX chemical warfare agent surrogates representing the amine (triethylamine) and organophosphonate (diethyl methythiomethylphosphonate (DEMTMP)) portions of VX. The measurements have been supplemented by theoretical calculations of the proton affinity, fluoride affinity, and ionization potential of VX and the simulants. The results show that many proton transfer reactions are rapid and that the proton affinity of VX is near the top of the scale. Many proton transfer agents should detect VX selectively and sensitively in chemical ionization mass spectrometers. Charge transfer with NO(+) should also be sensitive and selective since the ionization potential of VX is small. The surrogate studies confirm these trends. Limits of detection for commercial and research grade CIMS instruments are estimated at 80 pptv and 5 ppqv, respectively.

  1. Koncepcija partizanskoj vojny v Litve v 1920— 1930-e gody [The concept of guerrilla warfare in Lithuania in the 1920—1930s

    Directory of Open Access Journals (Sweden)

    Jokubauskas Vytautas


    Full Text Available This article analyses the military and tactical training of the members of the Lithuanian Riflemen’s Union for guerrilla warfare in the interwar period. Small nations, such as Lithuania and other Baltic states, being unable to build up military strength in order to ensure national security, were forced to seek for unconventional methods of warfare, including guerrilla strategies. The study places emphasis on the development of the guerrilla war concept in the Union periodicals. The author retraces a change in the intensity of the guerrilla warfare concept propagation amongst Lithuanian population and riflemen, in particular, through publications in the Trimitas — a periodical of the Lithuanian Riflemen’s Union. The author also identifies the narratives associated with the guerrilla matters employed for propaganda purposes in order to create an image of a guerrilla as a defender of the Homeland — Lithuania. Additionally, the structure and numbers of the Union are analysed through a comparison with similar organisations of the other «small nations» of the Baltic North-East. The author addresses the issue of military missions planned by the Lithuanian Army, as well as the way riflemen implemented them. Since the Union did not only offer military training, but was also engaged in the patriotic propaganda, the article focuses on the network of cultural institutions, homes of riflemen, orchestras, libraries, choirs, and athletic clubs used by the Union. The article sets out to establish whether the loss of Lithuanian sovereignty could have been possible without giving rise to a protracted guerrilla war.

  2. Real-time detection of concealed chemical hazards under ambient light conditions using Raman spectroscopy. (United States)

    Cletus, Biju; Olds, William; Fredericks, Peter M; Jaatinen, Esa; Izake, Emad L


    Current concerns regarding terrorism and international crime highlight the need for new techniques for detecting unknown and hazardous substances. A novel Raman spectroscopy-based technique, spatially offset Raman spectroscopy (SORS), was recently devised for noninvasively probing the contents of diffusely scattering and opaque containers. Here, we demonstrate a modified portable SORS sensor for detecting concealed substances in-field under different background lighting conditions. Samples including explosive precursors, drugs, and an organophosphate insecticide (chemical warfare agent surrogate) were concealed inside diffusely scattering packaging including plastic, paper, and cloth. Measurements were carried out under incandescent and fluorescent light as well as under daylight to assess the suitability of the probe for different real-life conditions. In each case, it was possible to identify the substances against their reference Raman spectra in less than 1 min. The developed sensor has potential for rapid detection of concealed hazardous substances in airports, mail distribution centers, and customs checkpoints.

  3. Decontamination and Management of Human Remains Following Incidents of Hazardous Chemical Release

    Energy Technology Data Exchange (ETDEWEB)

    Hauschild, Veronique [U.S. Army Public Health Command; Watson, Annetta Paule [ORNL; Bock, Robert Eldon [ORNL


    Abstract Objective: To provide specific procedural guidance and resources for identification, assessment, control, and mitigation of compounds that may contaminate human remains resulting from chemical attack or release. Design: A detailed technical, policy, and regulatory review is summarized. Setting: Guidance is suitable for civilian or military settings where human remains potentially contaminated with hazardous chemicals may be present. Settings would include sites of transportation accidents, natural disasters, terrorist or military operations, mortuary affairs or medical examiner processing and decontamination points, and similar. Patients, Participants: While recommended procedures have not been validated with actual human remains, guidance has been developed from data characterizing controlled experiments with fabrics, materiel, and laboratory animals. Main Outcome Measure(s): Presentation of logic and specific procedures for remains management, protection and decontamination of mortuary affairs personnel, as well as decision criteria for determining when remains are sufficiently decontaminated so as to pose no chemical health hazard. Results: Established procedures and existing equipment/materiel available for decontamination and verification provide appropriate and reasonable means to mitigate chemical hazards from remains. Extensive characterization of issues related to remains decontamination indicates that supra-lethal concentrations of liquid chemical warfare agent VX may prove difficult to decontaminate and verify in a timely fashion. Specialized personnel can and should be called upon to assist with monitoring necessary to clear decontaminated remains for transport and processing. Conclusions: Once appropriate decontamination and verification have been accomplished, normal procedures for remains processing and transport to the decedent s family and the continental United States can be followed.

  4. Formalization Modeling on VV&A Process for Warfare Simulation by UML%基于UML的作战仿真VV&A过程形式化建模

    Institute of Scientific and Technical Information of China (English)

    唐见兵; 查亚兵


    可信性是作战仿真的生命线,对作战仿真的全生命周期进行校核、验证与确认(Verification,Validation and Accreditation,VV&A)是确保其可信性的重要途径.建立合适的VV&A过程形式化模型是开展作战仿真VV&A过程研究的前提和基础.基于统一建模语言(Unified Modeling Language,UML)分别从用例、静态结构、动态行为及交互等方面对VV&A过程进行形式化建模,建立了作战仿真VV&A过程的用例、类图、活动图及顺序图模型,并给出相应的形式化定义.实践表明:作战仿真VV&A过程形式化建模可以使VV&A的描述规范化、标准化及形式化,便于不同领域人员的相互沟通与交流,以及VV&A工程化应用,促进了VV&A工作顺利开展.%The credibility is the lifeline of warfare simulation. To execute verification, validation and accreditation (VV&A) is an important approach to insure the credibility of warfare simulation system through out the life circle. It is the precondition and foundation to make the right formal model of VV&A process for warfare simulation. In this paper,the formal models of VV&A process is carried out,in which the details of use case,static construction,dynamic activities and interactions are modeled based on UML, and their formalization definitions are put forward. The practice shows that the formalization modeling on VV&A process for warfare simulation by UML can make it standardization, regularization and formalization,which can help the researchers in different domains to communicate with each other. The research of VV&A can be used in engineering,which help the job of VV&A is developed expediently.

  5. More Effective Warfare: Warfare Waged Psychologically (United States)


    Brotherhood’s Hamas wing. The wave of new members resulted in a more heterogeneous and expansive constituency for Hamas, who by now had surpassed the...utilized. They often possess a large appeal to people’s sense of nationalism through the use of songs, poetry , and stories rich with vivid imagery

  6. Optimization of Quantitative Proteomics Using 2-Dimensional Difference Gel Electrophoresis to Characterize Molecular Mechanisms of Chemical Warfare Nerve Agent Exposure in the Rat Brain (United States)


    damaging effects of nerve agents. Currently, one prophylactic (pyridostigmine) and three therapeutic drugs (atropine, pralidoxime chloride, and diazepam ...and J.H. McDonough, Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication. Archives of

  7. A comprehensive evaluation of the efficacy of leading oxime therapies in guinea pigs exposed to organophosphorus chemical warfare agents or pesticides

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelm, Christina M., E-mail: [Battelle, 505 King Avenue, JM-7, Columbus, OH 43201-2693 (United States); Snider, Thomas H., E-mail: [Battelle, 505 King Avenue, JM-7, Columbus, OH 43201-2693 (United States); Babin, Michael C., E-mail: [Battelle, 505 King Avenue, JM-7, Columbus, OH 43201-2693 (United States); Jett, David A., E-mail: [National Institutes of Health/National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 (United States); Platoff, Gennady E., E-mail: [National Institutes of Health/National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 (United States); Yeung, David T., E-mail: [National Institutes of Health/National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892 (United States)


    The currently fielded pre-hospital therapeutic regimen for the treatment of organophosphorus (OP) poisoning in the United States (U.S.) is the administration of atropine in combination with an oxime antidote (2-PAM Cl) to reactivate inhibited acetylcholinesterase (AChE). Depending on clinical symptoms, an anticonvulsant, e.g., diazepam, may also be administered. Unfortunately, 2-PAM Cl does not offer sufficient protection across the range of OP threat agents, and there is some question as to whether it is the most effective oxime compound available. The objective of the present study is to identify an oxime antidote, under standardized and comparable conditions, that offers protection at the FDA approved human equivalent dose (HED) of 2-PAM Cl against tabun (GA), sarin (GB), soman (GD), cyclosarin (GF), and VX, and the pesticides paraoxon, chlorpyrifos oxon, and phorate oxon. Male Hartley guinea pigs were subcutaneously challenged with a lethal level of OP and treated at approximately 1 min post challenge with atropine followed by equimolar oxime therapy (2-PAM Cl, HI-6 DMS, obidoxime Cl{sub 2}, TMB-4, MMB4-DMS, HLö-7 DMS, MINA, and RS194B) or therapeutic-index (TI) level therapy (HI-6 DMS, MMB4-DMS, MINA, and RS194B). Clinical signs of toxicity were observed for 24 h post challenge and blood cholinesterase [AChE and butyrylcholinesterase (BChE)] activity was analyzed utilizing a modified Ellman's method. When the oxime is standardized against the HED of 2-PAM Cl for guinea pigs, the evidence from clinical observations, lethality, quality of life (QOL) scores, and cholinesterase reactivation rates across all OPs indicated that MMB4 DMS and HLö-7 DMS were the two most consistently efficacious oximes. - Highlights: • First comprehensive evaluation of leading AChE oxime reactivators • All oximes are compared against current U.S. therapy 2-PAM Cl. • Relative therapeutic oxime efficacies against OP CWNA and pesticides • Contribution to more effective antidotes for civilian and military populations.

  8. US Army Order of Battle 1919-1941. Volume 4. The Services: Quartermaster, Medical, Military Police, Signal Corps, Chemical Warfare, and Miscellaneous Organizations, 1919-41 (United States)


    35-1 Jul 36 62nd Cavalry Division Quartermaster Train Organized Reserve Maryland/Virginia HQ-Not initiated 1921-22; Towson , MD, the 62nd Cavalry Division, and allotted to the Third Corps Area. Headquarters initiated in June 1922 at Towson , MD. Headquarters relocated about...RAI Commanders: Organized Reserve officers. 36th Quartermaster Regiment (Light Maintenance) (V Corps) Regular Army Inactive HQ-Fort Wayne

  9. Analysis of Chemical Warfare Agents: General Overview, LC-MS Review, In-House LC-ESI-MS Methods and Open Literature Bibliography (United States)


    isopropylaminoethyl O-ethyl methylphosphonothioate in soil sulphur-containing products. Pestic . Sci., 8, 510-514. 194. Kaipainen, A., Kostiainen, O. and...ethyl methylphosphonothioate in soil: Phosphorus containing products. Pestic . Sci., 7, 355-362. DRDC Suffield TR 2006-022 73 413. Verweij

  10. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 1st Division in the Meuse-Argonne 1-12 October 1918 (United States)


    October, instead of 30 September-I October 0 On the night of the relief the .Jnemy began shelling at 10s00 porn October 1st and continued until 4s00... Juvin and Landre, out off the Argoure front, and attack in rear of the Brunhild position to effect decisive action on the Group -Argonnej." 8 7 At...attack, fired on the Son’.erance area and north of St Georges et Landres, Juvin , Marcq, and Champigxeulle. 93 Company C, 1st Gas Regiment, was ordered

  11. Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) Analysis of Organophosphorus Chemical Warfare Agents: Rapid Acquisition of Time-Aligned Parallel (TAP) Fragmentation Data (United States)


    L’installation récente du nouveau spectromètre de masse en tandem Synapt HDMSMC à haute résolution à la RDDC Suffield devrait permettre de poursuivre le... art and future prospects. J. Chromatogr. A, 814, 1- 23. [2] Munro, N.B., Talmage, S.S., Griffin, G.D., Waters, L.C., Watson, A.P., King, J.F. and

  12. Liquid Chromatography Electrospray Ionization Mass Spectrometric (LC-ESI-MS) and Desorption Electrospray Ionization Mass Spectrometric (DESI-MS) Identification of Chemical Warfare Agents in Consumer Products (United States)


    au-dessus des 6chantillons de semoule de mais et d’huile de soja ensemenc6s ont &6 6chantillonn6s avec des fibres SPME; ces fibres ont &6 analys6s au...6chantillons d’eau embouteill6e. Les vides au-dessus des 6chantillons de semoule de mais et d’huile de soja ensemencds ont 6t6 6chantillonn~s avec...des fibres SPNM. L’analyse directe des fibres SPME ayant 6t6 exposes dans le vide au-dessus des 6chantillons de la semoule de mais et I’huile de soja

  13. An in vitro and in vivo Evaluation of the Efficacy of Recombinant Human Liver Prolidase as a Catalytic Bioscavenger of Chemical Warfare Nerve Agents (United States)


    preparation used in the previous study (Costante et al., 2012) was 70 to 80% pure and its gel image was not shown. In vivo protection offered by rhProlidase... monkeys . Chem Biol Interact 157–158:205–210. Lenz DE, Yeung D, Smith JR, et al. (2007). Stoichiometric and catalytic scavengers as protection against nerve...rhesus monkeys against soman toxicity. Toxicol Appl Pharmacol 117:189–193. Yokoyama K, Araki S, Murata K, et al. (1998). Chronic neurobehavioral and

  14. Application of Solid Phase Microextraction with Gas Chromatography-Mass Spectrometry as a Rapid, Reliable, and Safe Method for Field Sampling and Analysis of Chemical Warfare Agent Precursors (United States)


    nations, including plating solutions, metallurgical processes such as silver and gold refining, and as an intermediate in the manufacture of resin...used in numerous processes in industrial nations, including plating and other metallurgical processes such as silver and gold refining, and as an...malononitrile, diisopropyl methylphosphonate (DIMP), diethyl methylphosphonate (DEMP), malathion, potassium cyanide , and O,O’diethyl methyl

  15. First NATO/SIBCA Exercise in Sampling of Chemical Warfare Agents (Eerste NATO/SIBCA-oefening in monstername van chemische strijdmiddelen). (United States)


    gesloten overeenkomst. Het ter inzage geven van net TNO-rapport aan direct belang- hebbenden is toegestaan. Titel Manage mentuittreksel Samenvatting... contents of the sampling kit adequate to take at least 10 samples of all necessary types (air, soil, water, materials) 2.2 Are primary sample...pincetten in de potten of zakken gebracht. Voor vloeistofmonsters is een monsternamesysteem aanwezig dat gebaseerd is op een systeem om bloedmonsters te

  16. Validation and Support of a Quantitative Infrared Instrument Facility and Generation of a Library of Chemical Warfare and Related Materials by Fourier Transform Infrared Spectroscopy (United States)


    National Laboratory, personal communication . 7. A. G. Maki, J. S. Wells. Wavenumber Calibration Tables from Heterodyne Frequency Measurements (version 1.3...Barker. Phys. Rev., 18, 1551 (1931). 9. P. M. Chu. personal communication . 10. W. J. Barrett, E. B. Dismukes. AD 506023, Infrared Spectral Studies of...hritianen ffet inthespetra.Thi efect trnsisse1. rionintescral rnegtiontis adjcent tof the absorptiont Cobacinds should.3 beromie in aamrethortional

  17. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 92nd Division in the Marbache Sector, October 1918 (United States)


    Dromadaire Trenches. Elser’s 2nd Battalion advanced about two kilometers against considerably more opposi- tion than it had met the first day but got... Dromadaire Trench and then send forces towards the town of Binarville, the 2nd Battalion advanced approximately 800 meters, just beyond Tirpitz Trench, came within 200 meters of Dromadaire Trench before machine gun fire supported by an artillery barrage halted it. All but a company retired without

  18. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 89th Division in the Bois de Bantheville, October 1918 (United States)


    move up between Eclisfontaine and Epinonville, in support of Haanfs 32nd Division. The 32nd had taken Cierges and Gesnes and was then getting set...24 - 25 Oct (89th Div Box 12, 20.7), said 51 Americans and 20 Germans were buried weit of Gesnes where they fell and 7 Americans and 2 Germans in the...Get (GFB 164, fol II, pp» 59 - 61). 42 DOR 70, 89th Div, 19-20 Oct (89th Div Box 19, 33.1)* - 23 - heights of Bois de Gesnes - Cote Dame Marie

  19. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War 1: The 33rd Division along the Meuse, October 1918 (United States)


    disorganized detachments, dug in along Dana lea Vaux valley and through the woods east to Meridian 24a Un- der heavy macohine gun, shell, and gas fire , it...Div J58 Throughout the night of 3. - 11 October and the following day inces- sant high explosive, machine gun, and gas fire hampered the division would have been remarkable if the Incessent enemy EX and gas fire , unhampered by divisional efforts to still it, had not produced evidence of gas

  20. U.S. Army Chemical Corps Historical Studies Gas Warfare in World War I: The 26th Division East of the Meuse, September 1918 (United States)


    and 139 artillerymen, or 237* The gas fire and the HE bombardment that began as the raiders advanced and continued through the day destroyed all...not distinguish between the projector 34 attack and the later gas fire * The Regimental Gas Officer of the 103rd Infantry thought no more than 300...strongpoints in the Bois de Crepion, Ravin de la Hazelle, and Ravin du Chuchu, masking the gas fire with high explosives. A mortar platoon of the 1st Gas

  1. U. S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 32nd Division Advances to Fismes, August 1918 (United States)


    cross gas ammunition will be employed during the fighting and move- ,.1* • ment...whenever the supply permits. But the rules governing gas fire must...the yellow cross fire that night, there is not a word in 32nd Divi- sion or Division Gas Officer records, unless reports of gas fire during the day of 4...August refer to enemy HE fire on areas contaminated during the previous night, so that the effect was that of mixed HE and gas fire . German . records

  2. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The Use of Gas at Saint Mihiel (90th Division in September 1918) (United States)


    another thousand Casualties a3 a result of daily gas fire . Its gas casualties for the period were almost one-third of its total battle casualties...same scale as the German gas fire . Exact quantities could not he reported that first week, but "since the attack considerable quantities of gas shell... gas fire in the early morning between Preny and Zugspitze (the draw east of Preny) and that evening the gassing of Pagny.87 Again on the morning and

  3. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 1st Division at Ansauville, January-April 1918 (United States)


    princip•al target of both enemy HE and gas fire at Ansauville was the 1st Division artillery, not the infantry. On both quiet and active fronts in the...of the gas fire was postponed on account of storm and rain. 434 JA. % *.. .. t .. t-. ,t. ,t.,,.4.:’... ,, ’. . w’. * ." .7 . , , , q I Io thought...against the enemy with gas fire . Butler’s journal indicates much more frequent use of gas, and this is confirmed by the artillery brigade summary which

  4. U. S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 29th Division in the Cotes de Meuse, October 1918 (United States)


    part to the HE and gas fire coming from the heights of the Meuse. Four days later the 33rd and 29th Divisions were put across the river and ordered great concentrations in the Meuse area, the divi- sion was lulled at the start by the relatively light and widely dispersed gas fire in the sector...rear by their companions. 2 9 Both G -2 and Captain Maynard, the Division Gas Office2, made light of the enemy gas fire those first few days. The

  5. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The End of the Aisne-Marne Campaign, August 1918 (United States)


    fol 27): "Heavy yellow cross gas fire along the entire front of the army was carried out during the morning hours according to orders." - 14 - of the... gas fire day after day. Arnd as had been observed in other divisions, incessant gassing over a period of time tended to breed a degree of morbidity in...gas cases.... The single attempt to retaliate in kind for the enemy’s iunishing gas fire occurred On the morning of August 28th... L[hen] our own

  6. Abdominal bloating and irritable bowel syndrome like symptoms following microinstillation inhalation exposure to chemical warfare nerve agent VX in guinea pigs. (United States)

    Katos, Alexandre M; Conti, Michele L; Moran, Theodore S; Gordon, Richard K; Doctor, Bhupendra P; Sciuto, Alfred M; Nambiar, Madhusoodana P


    While assessing the methylphosphonothioic acid S-(2-(bis(1-methylethyl)amino)ethyl)O-ethyl ester (VX) induced respiratory toxicity and evaluating therapeutics against lung injury, we observed that the animals were experiencing abnormal swelling in the abdominal area. Nerve agent has been known to increase salivary, nasal and gastrointestinal secretion and cause diarrhea. This study was initiated to investigate the effect of VX on the gastrointestinal tract (GI) since abdominal pathology may affect breathing and contribute to the on going respiratory toxicity. The mid-abdominal diameter and the size of the lower left abdomen was measured before and after 27.3 mg/m3 VX exposure by microinstillation and at 30 min intervals up to 2 h post-VX exposure. Both VX and saline exposed animals exhibited a decrease in circumference of the upper abdomen, although the decrease was slightly higher in VX-exposed animals up to 1 h. The waist diameter increased slightly in VX-exposed animals from 60 to 90 min post-VX exposure but was similar to saline controls. The lower left abdomen near to the cecum, 6 cm below and 2cm to the right of the end of the sternum, showed an increase in size at 30-60 min that was significantly increased at 90-120 min post-VX exposure. In addition, VX-exposed animals showed loose fecal matter compared to controls. Necropsy at 24h showed an increased small intestine twisting motility in VX-exposed animals. Body tissue AChE assay showed high inhibition in the esophagus and intestine in VX-exposed animals indicating that a significant amount of the agent is localized to the GI following microinstillation exposure. These results suggest that microinstillatipn inhalation VX exposure induces gastrointestinal disturbances similar to that of irritable bowel syndrome and bloating.

  7. A Comparison of QSAR Based Thermo and Water Solvation Property Prediction Tools and Experimental Data for Selected Traditional Chemical Warfare Agents and Simulants (United States)


    report does not constitute an official endorsement of any commercial products . This report may not be cited for purposes of advertisement. the fact that the nitrogen atom is joined to two ethyl groups. A fate model may predict rapid dissipation for this compound using the the prediction for nitrogen mustard (HN1) for EPI Suite. Examining the EPI Suite output, it appears only basic atomic fragments of Cl, thio- ether

  8. Microfluidic chemical reaction circuits (United States)

    Lee, Chung-cheng; Sui, Guodong; Elizarov, Arkadij; Kolb, Hartmuth C.; Huang, Jiang; Heath, James R.; Phelps, Michael E.; Quake, Stephen R.; Tseng, Hsian-rong; Wyatt, Paul; Daridon, Antoine


    New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.

  9. Chemical Security Analysis Center (United States)

    Federal Laboratory Consortium — In 2006, by Presidential Directive, DHS established the Chemical Security Analysis Center (CSAC) to identify and assess chemical threats and vulnerabilities in the...

  10. Biochemical warfare on the reef: the role of glutathione transferases in consumer tolerance of dietary prostaglandins.

    Directory of Open Access Journals (Sweden)

    Kristen E Whalen

    generalist's GSTs may operate as 'all-purpose' detoxification enzymes, capable of conjugating or sequestering a broad range of lipophilic gorgonian compounds, thereby allowing this predator to exploit a range of chemically-defended prey, resulting in a competitive dietary advantage for this species.

  11. 信息化条件下计划制定与行动实施的关系%Relationship between planning and execution in information warfare

    Institute of Scientific and Technical Information of China (English)

    田仲; 李加祥


    信息化条件下的作战引发了作战指挥方式等一系列的变化,对作战计划制定与作战行动实施的关系也产生了深刻的影响.以信息化条件下“以行动为中心”的作战需求为牵引,以提升作战指挥的适应性和时效性为目的,对不同方式的计划制定与行动实施的关系进行对比分析和研究,提出了适应行动中心方式下的计划制定与行动实施关系,为深入开展信息化条件下的作战指挥研究提供了有益的参考.%Command approaches changes in information operation impact relationship between planning and execution. With the purpose to meet the demands of " operation -centric" in information warfare, and to improve the agility and timeliness for command, different approaches of planning and execution are analyzed and researched, the relationship between planning and execution suit for operation-centric approach is advanced. Therefore,it has reference value for study the command in information warfare.

  12. 中国共产党领导的抗日心理战%Anti-Japanese Psychological Warfare Led by the Chinese Communist Party

    Institute of Scientific and Technical Information of China (English)



    During the Anti-Japanese War ,the Chinese Communist Party creatively applied the ancient Chinese mili-tary’s psychological warfare and developed psychological tactics .By conducting political psychological attacking and im-plementing POW policy and other measures to constantly shake ,lax and abate enemy psychological defense ,our Party achieved remarkable success because with the development of the war ,the psychological defense of the Japanese invaders gradually collapsed ,and the Chinese people finally won the victory in the Anti-Japanese psychological warfare .%抗日战争中,我党继承和发扬了中国古代兵家的心战思想,创造性地运用和发展了心理战术,取得了举世瞩目的战果。我军民通过开展政治攻心和实施俘虏政策等措施,不断动摇、涣散、消减敌军的士气军心,使日本侵略者的军心随着战争的发展而日渐动摇和瓦解,我国人民最终赢得了抗日心理战的胜利。

  13. Isolated iliotibial band rupture after corticosteroid injection as a cause of subjective instability and knee pain in a military special warfare trainee. (United States)

    Pandit, Sandeep R; Solomon, Daniel J; Gross, Daniel J; Golijanin, Petar; Provencher, Matthew T


    Iliotibial band friction syndrome (ITBFS) of the knee is a common overuse injury in athletes, especially in runners. The syndrome occurs when the ITB, a lateral thickening of the fascia lata of the thigh moves repetitively over the lateral femoral condyle. A variety of nonoperative measures are used for ITBFS treatment, including stretching, core strengthening, and therapeutic injection. Isolated distal ITB rupture is a rare entity and has never yet to be reported in the orthopedic literature. We present a case of isolated ITB rupture as a cause of varus instability and knee pain in a Naval Special Warfare candidate diagnosed with ITBFS and previously treated with several local corticosteroid injections before ITB rupture. Because of continued knee pain and a sense of instability, along with an inability to return to his military special warfare duties, the ITB was surgically repaired. This case highlights the presentation and management of isolated distal ITB rupture and discusses some of the potential risk factors for rupture, including prior local corticosteroid injection.

  14. Application of Antibiotic on Sea Warfare Wound in Marine Environment%抗生素在海上环境下海战伤中的应用

    Institute of Scientific and Technical Information of China (English)

    张贞良; 贺顺龙; 谢培增; 汪先兵


    Objective To study an appropriate anti-inflammation treatment strategy on sea warfare wound in ma-rine environment Methods Animal model of combined sea warfare wound in marine environment was established in 40 mongrel dogs. The dogs were randomly divided into control group and treatment group. The control group accepted rou-tine cefodizime treatment, and the treatment group accepted cefodizime plus levofloxacin treatment The treatment on sea warfare wound was the same in both groups. The gross condition was observed and bacteriological strains in the wound were cultured and antibiotic sensitivity was tested at 2 and 4 days after the wound. Wound infection rate and mortality were observed at the sixth day. Results The infection rate within six days was 50% in the control group, and 10% in treatment group, and the mortality was 60% and 20% respectively. These rates were significantly lower in the treatment group than those in the control group (P<0. 01). The constituent ratio of vibrion in the treatment group was lower than that in the control group (P<0. 01). Conclusion There are many species of bacteria with wide distribution in South China Sea which mainly includes vibrionaceaes, staphylococcus and escherichia. These bacteria are the main causes leading to sea warfare wound infection. To deal with the sea warfare wound in marine environment, the early and complete debride-ment, and the early application of broadspectrum and anti-vibrion antibiotics should be emphasized.%目的 探讨抗生素在海上环境下海战伤中的有效应用.方法 选取40只成年杂种犬,制作海上环境下海水浸泡复合火器伤动物模型.随机将动物分成对照组和治疗组,每组20只犬.对照组采用头孢地嗪治疗,治疗组头孢地嗪加左氧氟沙星治疗.海战伤的其他处理方法相同.在伤后第2和第4天进行细菌培养与药敏试验,观察6天伤口感染率、死亡率.结果 伤后6天,对照组的伤口感染率为500,治疗组为10

  15. 基于组件技术的分布式潜艇作战仿真系统%Research of Distributed Submarine Warfare Simulation System Based on Component

    Institute of Scientific and Technical Information of China (English)

    王永洁; 陆铭华; 史扬


    提出采用JavaEE/EJB组件技术开发分布式潜艇作战仿真系统,根据潜艇作战机理,建立了分布式潜艇作战仿真模型体系结构,设计了分布式潜艇作战仿真系统的软件架构,分析了系统开发过程中采用的技术协议,并研究了基于组件技术的分布式潜艇作战仿真系统实现方法。%This paper puts forward to develop distributed submarine warfare simulation system with Java EE/EJB component technology. Model component architecture is compartmentalized according to submarine warfare logic. The paper designs software structure of distributed submarine warfare simulation system,analyzes technology protocol of the system, and researches realization way of distributed submarine warfare simulation system.

  16. Innovative permeable cover system to reduce risks at a chemical munitions burial site

    Energy Technology Data Exchange (ETDEWEB)

    Powels, C.C. [Army Garrison, Aberdeen Proving Ground, MD (United States); Bon, I. [Army Corps. of Engineers, Aberdeen Proving Ground, MD (United States); Okusu, N.M. [ICF Kaiser Engineering, Savannah, GA (United States)


    An innovative permeable sand cover with various integrated systems has been designed to contain and treat the Old O-Field chemical munitions landfill at Aberdeen Proving Ground, Maryland. The 18,200 m{sup 2} (4.5 acre) landfill was used from the mid 1930s to the mid 1950s for the disposal of chemical, incendiary, and explosive munitions from domestic and foreign origins, together with contaminated wastes associated with the development and production of chemical warfare agents (CWA). The site is suspected to be contaminated with white phosphorous (WP) (which when dry, spontaneously burns when exposed to air), shock sensitive picric acid fuses and has the potential to contain large quantities of CWA-filled munitions. Historically, one to three explosions or fires occurred per ten-year period at the landfill. Such events have the potential to cause a CWA release to the environment, which could potentially affect densely populated areas. Recovery and decontamination projects conducted at the site in the late 1940s and early 1950s used large amounts of decontamination chemicals (containing solvents) and fuels which further contaminated the area. The groundwater downgradient of the landfill is contaminated with volatile organic compounds, metals, explosives and CWA degradation compounds and is currently being contained by a groundwater extraction and treatment system. This report describes a remedial action program for the site.

  17. Arsenic concentrations in Baltic Sea sediments close to chemical munitions dumpsites (United States)

    Bełdowski, Jacek; Szubska, Marta; Emelyanov, Emelyan; Garnaga, Galina; Drzewińska, Anna; Bełdowska, Magdalena; Vanninen, Paula; Östin, Anders; Fabisiak, Jacek


    In addition to natural sources and land-originated pollution, the Baltic Sea has another anthropogenic source of arsenic in bottom sediments-arsenic-based Chemical Warfare Agents (CWA). To examine the potential usage of arsenic contents results for monitoring the leakage from chemical weapons, sediment samples were collected from officially reported and potential chemical weapon dumpsites located in the Baltic Sea, and total and inorganic arsenic concentrations were analyzed. Results showed an elevated arsenic content in dumpsite areas compared to reference areas. Correlations of arsenic with other metals and organic matter were studied to elucidate any unusual behavior of arsenic in the dumpsites. In the area of the Bornholm Deep, such behavior was observed for inorganic arsenic. It appears that in close vicinity of dumped munitions, the inorganic arsenic concentration of sediments is not correlated with either organic matter content or authigenic minerals formation, as is commonly observed elsewhere. Investigations on CWA concentrations, performed within the CHEMSEA (Chemical Munition Search and Assesment) project, allowed us to compare the results of arsenic concentrations with the occurrence of arsenic-containing CWA.

  18. The chemical life(1). (United States)

    Hodges, Nathan


    You write this narrative autoethnography to open up a conversation about our chemical lives. You go through your day with chemical mindfulness, questioning taken-for-granted ideas about natural and artificial, healthy and unhealthy, dependency and addiction, trying to understand the chemical messages we consume through the experiences of everyday life. You reflect on how messages about chemicals influence and structure our lives and why some chemicals are celebrated and some are condemned. Using a second-person narrative voice, you show how the personal is relational and the chemical is cultural. You write because you seek a connection, a chemical bond.

  19. Counter-Chemical, Biological, Radiological, and Nuclear Operations (United States)


    Present. [Order from DTIC-E, 8725 John J. Kingman Road, Suite 0944, Ft Belvoir, VA 22060-6218.] Douglas, Joseph, and Livingstone, Neil , America the...Harris, Sheldon H ., Factories of Death: Japanese Biological Warfare, 1932-45, and the American Cover-up (Routledge). 1994. Hayes, Peter L...Biological Warfare (Office of Surgeon General, Borden Institute). 1997. Sloan, Steven, Beating International Terrorism (Air University Press). 1986

  20. Existing chemicals: international activities. (United States)

    Purchase, J F


    The standards of care used in the protection of the health and safety of people exposed to chemicals has increased dramatically in the last decade. Standards imposed by regulation and those adopted by industry have required a greater level of knowledge about the hazards of chemicals. In the E.E.C., the 6th amendment of the dangerous substances directive imposed the requirement that al new chemicals should be tested according to prescribed programme before introduction on to the market. The development of a European inventory of existing chemicals was an integral part of the 6th amendment. It has now become clear that increased standards of care referred to above must be applied to the chemicals on the inventory list. There is, however, a considerable amount of activity already under way in various international agencies. The OECD Chemicals Programme has been involved in considering the problem of existing chemicals for some time, and is producing a priority list and action programme. The International Programme on Chemical Safety produces international chemical safety cards, health and safety guides and environmental health criteria documents. The international register of potentially toxic compounds (part of UNEP) has prepared chemical data profiles on 990 compounds. The International Agency for Research on Cancer prepared monographs on the carcinogenic risk of chemicals to man. So far 42 volumes have been prepared covering about 900 substances. IARC and IPCS also prepare periodic reports on ongoing research on carcinogenicity or toxicity (respectively) of chemicals. The chemical industry through ECETOC (the European Chemical Industry Ecology and Toxicology Centre) has mounted a major initiative on existing chemicals. Comprehensive reviews of the toxicity of selected chemicals are published (Joint Assessment of Commodity Chemicals). In its technical report no. 30 ECETOC lists reviews and evaluations by major national and international organisations, which provides

  1. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A


    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics. This volume explores: Quantum Dynamical Resonances in Ch

  2. Geopolitical Trends and Security Challenges across the Indian Ocean and Asia-Pacific Regions; Strategic Insights, v. 10, Special issue (October 2011), 28-35. Topic: Global Trends and Future Warfare ; Part I: Alternative Perspectives: Traditional Powers, Rising Powers, and the Developing World


    Parthasarathy, G.


    This article appeared in Strategic Insights, v.10, Special issue (October 2011), 28-35. Topic: Global Trends and Future Warfare ; Part I: Alternative Perspectives: Traditional Powers, Rising Powers, and the Developing World Approved for public display, distribution unlimited

  3. Halomonhystera disjuncta - a young-carrying nematode first observed for the Baltic Sea in deep basins within chemical munitions disposal sites (United States)

    Grzelak, Katarzyna; Kotwicki, Lech


    Three deep basins in the Baltic Sea were investigated within the framework of the CHEMSEA project (Chemical Munitions Search & Assessment), which aims to evaluate the ecological impact of chemical warfare agents dumped after World War II. Nematode communities, which comprise the most numerous and diverse organisms in the surveyed areas, were investigated as a key group of benthic fauna. One of the most successful nematode species was morphologically identified as Halomonhystera disjuncta (Bastian, 1865). The presence of this species, which is an active coloniser that is highly resistant to disturbed environments, may indicate that the sediments of these disposal sites are characterised by toxic conditions that are unfavourable for other metazoans. Moreover, ovoviviparous reproductive behaviour in which parents carry their brood internally, which is an important adaptation to harsh environmental conditions, was observed for specimens from Gdansk Deep and Gotland Deep. This reproductive strategy, which is uncommon for marine nematodes, has not previously been reported for nematodes from the Baltic Sea sediment.

  4. Capacitive chemical sensor (United States)

    Manginell, Ronald P; Moorman, Matthew W; Wheeler, David R


    A microfabricated capacitive chemical sensor can be used as an autonomous chemical sensor or as an analyte-sensitive chemical preconcentrator in a larger microanalytical system. The capacitive chemical sensor detects changes in sensing film dielectric properties, such as the dielectric constant, conductivity, or dimensionality. These changes result from the interaction of a target analyte with the sensing film. This capability provides a low-power, self-heating chemical sensor suitable for remote and unattended sensing applications. The capacitive chemical sensor also enables a smart, analyte-sensitive chemical preconcentrator. After sorption of the sample by the sensing film, the film can be rapidly heated to release the sample for further analysis. Therefore, the capacitive chemical sensor can optimize the sample collection time prior to release to enable the rapid and accurate analysis of analytes by a microanalytical system.

  5. Tobacco and chemicals (image) (United States)

    Some of the chemicals associated with tobacco smoke include ammonia, carbon dioxide, carbon monoxide, propane, methane, acetone, hydrogen cyanide and various carcinogens. Other chemicals that are associated with chewing ...

  6. Chemical Industry Bandwidth Study

    Energy Technology Data Exchange (ETDEWEB)



    The Chemical Bandwidth Study provides a snapshot of potentially recoverable energy losses during chemical manufacturing. The advantage of this study is the use of "exergy" analysis as a tool for pinpointing inefficiencies.

  7. Chemical Search Web Utility (United States)

    U.S. Environmental Protection Agency — The Chemical Search Web Utility is an intuitive web application that allows the public to easily find the chemical that they are interested in using, and which...

  8. Chemicals Industry Vision

    Energy Technology Data Exchange (ETDEWEB)



    Chemical industry leaders articulated a long-term vision for the industry, its markets, and its technology in the groundbreaking 1996 document Technology Vision 2020 - The U.S. Chemical Industry. (PDF 310 KB).

  9. Organic Chemical Attribution Signatures for the Sourcing of a Mustard Agent and Its Starting Materials

    Energy Technology Data Exchange (ETDEWEB)

    Fraga, Carlos G.; Bronk, Krys; Dockendorff, Brian P.; Heredia-Langner, Alejandro


    Chemical attribution signatures (CAS) are being investigated for the sourcing of chemical warfare (CW) agents and their starting materials that may be implicated in chemical attacks or CW proliferation. The work reported here demonstrates for the first time trace impurities produced during the synthesis of tris(2-chloroethyl)amine (HN3) that point to specific reagent stocks used in the synthesis of this CW agent. Thirty batches of HN3 were synthesized using different combinations of commercial stocks of triethanolamine (TEA), thionyl chloride, chloroform, and acetone. The HN3 batches and reagent stocks were then analyzed for impurities by gas chromatography/mass spectrometry. Reaction-produced impurities indicative of specific TEA and chloroform stocks were exclusively discovered in HN3 batches made with those reagent stocks. In addition, some reagent impurities were found in the HN3 batches that were presumably not altered during synthesis and believed to be indicative of reagent type regardless of stock. Supervised classification using partial least squares discriminant analysis (PLSDA) on the impurity profiles of chloroform samples from seven stocks resulted in an average classification error by cross-validation of 2.4%. A classification error of zero was obtained using the seven-stock PLSDA model on a validation set of samples from an arbitrarily selected chloroform stock. In a separate analysis, all samples from two of seven chloroform stocks that were purposely not modeled had their samples matched to a chloroform stock rather than assigned a “no class” classification.

  10. Chemical Munitions Search & Assessment-An evaluation of the dumped munitions problem in the Baltic Sea (United States)

    Bełdowski, Jacek; Klusek, Zygmunt; Szubska, Marta; Turja, Raisa; Bulczak, Anna I.; Rak, Daniel; Brenner, Matthias; Lang, Thomas; Kotwicki, Lech; Grzelak, Katarzyna; Jakacki, Jaromir; Fricke, Nicolai; Östin, Anders; Olsson, Ulf; Fabisiak, Jacek; Garnaga, Galina; Nyholm, Jenny Rattfelt; Majewski, Piotr; Broeg, Katja; Söderström, Martin; Vanninen, Paula; Popiel, Stanisław; Nawała, Jakub; Lehtonen, Kari; Berglind, Rune; Schmidt, Beata


    Chemical Munitions Search & Assessment (CHEMSEA) project has performed studies on chemical weapon (CW) detection, sediment pollution and spreading as well as biological effects of chemical warfare agents (CWAs) dumped in the Baltic Sea. Results suggest that munitions containing CWAs are more scattered on the seafloor than suspected, and previously undocumented dumpsite was discovered in Gdansk Deep. Pollution of sediments with CWA degradation products was local and close to the detected objects; however the pollution range was larger than predicted with theoretical models. Bottom currents observed in the dumpsites were strong enough for sediment re-suspension, and contributed to the transport of polluted sediments. Diversity and density of the faunal communities were poor at the dumping sites in comparison to the reference area, although the direct effects of CWA on benthos organisms were difficult to determine due to hypoxic or even anoxic conditions near the bottom. Equally, the low oxygen might have affected the biological effects assessed in cod and caged blue mussels. Nonetheless, both species showed significantly elevated molecular and cellular level responses at contaminated sites compared to reference sites.

  11. Distribution-mode Logistical Support in Modern Warfare%现代战争条件下的配送式后勤保障

    Institute of Scientific and Technical Information of China (English)

    吴兆东; 朱江浩


    The distribution-mode logistical support is the product of the warfare in the information era and has become a basic form of the modern logistical practices. In this paper, in connection with the characteristics of military distribution and transportation, we analyzed the logistical support mode of the U.S. army in the war in Iraq and then proposed some thoughts on building the distribution-mode logistical support system by the Chinese army.%配送式后勤保障是信息化条件下的战争产物,已成为现代后勤保障的基本形式.结合军事物流配送的特点,分析了伊拉克战争中美军这种后勤保障模式的特点,提出关于我军配送式后勤保障建设的思考.

  12. Chemical Physics Courses. (United States)

    Lee, J.; Munn, R. W.


    This is a guide to the chemical physics major. The scope of chemical physics is presented, along with the general features of course contents and possible course structures. This information was derived from a survey of British universities and colleges offering undergraduate degree courses in chemical physics. (BB)

  13. Chemical Recycle of Plastics

    Directory of Open Access Journals (Sweden)

    Sara Fatima


    Full Text Available Various chemical processes currently prevalent in the chemical industry for plastics recycling have been discussed. Possible future scenarios in chemical recycling have also been discussed. Also analyzed are the effects on the environment, the risks, costs and benefits of PVC recycling. Also listed are the various types of plastics and which plastics are safe to use and which not after rcycle

  14. Chemicals for worldwide aquaculture (United States)

    Schnick, R.A.


    Regulations and therapeutants or other safe chemicals that are approved or acceptable for use in the aquaculture industry in the US, Canada, Europe and Japan are presented, discussing also compounds that are unacceptable for aquaculture. Chemical use practices that could affect public health are considered and details given regarding efforts to increase the number of registered and acceptable chemicals.

  15. Çanakkale Savaşlarına Sualtından Bir Bakış A Look From Underwater to The Çanakkale Warfares

    Directory of Open Access Journals (Sweden)

    H.Barış ÖZALP


    Full Text Available Çanakkale Naval Warfares can basically be defined as a historic moment that tells of the campaign for liberation of its country and the state of defence of a nation’s capital. The importance of all battles taken place in Çanakkale surely are not ignored in winning the war, but the attacks occured around the coastal waters of Çanakkale Strait and Gallipoli Peninsula and sinking of the opposer’s ships and submarines can be evaluated as a significant information which is a proof that the strait can not be surpassed. If the enemy naval forces could not kept down and as a result of this, their willing to arrive at østanbul had come true, the success in Gallipoli campaign was not able to obtain. That can be stated that all arrangements planned by the Entente Powers on succeeding in war are primarily about the passing the Çanakkale Strait. Since the enemy forces and submarines have been stopped with severe damage or sunk, there have achieved success in naval battles and it was accepted by all the enemy forces that the strait was impassable. In this success, the powerfull emplacements deployed on both sides of the strait and our submarines and besides the mines laid by the Minelayer Nusret had a great effect. In Naval Warfares, many battleships and submarines owned by Entente Powers were sunk in the Çanakkale Strait and not allowed to drive into the sea of Marmara. Thus, all the plans of Entente Powers aim for conquering østanbul were interrupted and their will on winning in naval battle has been obstructed.

  16. [The re-introduction of malaria in the Pontine Marshes and the Cassino district during the end of World War II. Biological warfare or global war tactics?]. (United States)

    Sabbatani, Sergio; Fiorino, Sirio; Manfredi, Roberto


    After the fall of the Fascist regime on September 8, 1943, Italy was split into two parts: (i) the Southern regions where the King Victor Emanuel III and the military general staff escaped was under the control of English-American allied armies, and (ii) the northern regions comprising Lazio, Tuscany, Umbria, and Marche still under the control of the Germans. The German Wehrmacht, after suffering several defeats on Southern lines, established a new strengthened line of defence called the Gustav line, located south of Rome and crossing in the western portion the recently-drained Pontine Marshes. In his book published in 2006, Frank Snowden hypothesised that occupying German armies in 1943 had initiated a programme of re-flooding the Pontine plain as a biological warfare strategy to re-introduce malaria infection in the territories south of Rome, Such a plan was intended (i) to slow down the advance of English-American forces, and (ii) to punish Italians who abandoned their former allies. Other authors, including Annibale Folchi, Erhard Geissler, and Jeanne Guillemin, have disputed this hypothesis based on an analysis of recently-uncovered archive documents. What is not disputed is that the flooding of the Pontine and Roman plains in 1943 contributed to a severe malaria epidemic in 1944, which was associated with exceptionally high morbidity and mortality rates in the afflicted populations. Herein, we critically evaluate the evidence and arguments of whether the Wehrmacht specifically aimed to spread malaria as a novel biological warfare strategy in Italy during the Second World War. In our opinion, evidence for specific orders to deliberately spread malaria by the German army is lacking, although the strategy itself may have been considered by Nazis during the waning years of the war.

  17. Counterworking to UAN in Underwater Acoustic Warfare%水声对抗中的水声网络及其对抗

    Institute of Scientific and Technical Information of China (English)

    董阳泽; 许肖梅; 刘平香


    水声对抗系统和技术的不断发展是和相关技术的发展分不开的.一方面,传统威胁目标的智能化程度的提高,使得水声对抗技术必须在纵深方向做出应对;另一方面,威胁目标种类的扩展,使得水声对抗技术必须面临新的挑战,开阔思路,寻求应对方法.其中,水声网络的出现对于水声对抗的影响将是革命性的.分析了网络化条件下水声对抗技术发展的思路,特别是针对水声网络的对抗进行了分析和思考.%Development of Underwater Acoustic Warfare (UAW) system and technologies is tightly associated with relevant progresses. On one hand, traditional threats such as torpedoes have greatly improved their intelligence, which makes countermeasures must be deeply studied. On the other hand, types of threats have been extended largely, so new measures must be taken to confront such threats. Thereinto, Underwater Acoustic Networks (UAN) is a completely new concept in UAW, which is introduced under the background of Network-Centric Warfare (NCW). As to the recent cognition, the influence of UAN to UAW is revolutionary. This report analyzes the development considerations of UAW under conditions of NCW, and special thoughts are focused on the countermeasures to UAN.

  18. Truth about the Consequence of Bacteriological Warfare of Disseminating Plague Bacteria%散布鼠疫菌(PX)细菌战“战果”之真相

    Institute of Scientific and Technical Information of China (English)

    莇昭三[日](著); 韩慧光(译)


    日本军在中国实施细菌战的事实,随着中日学者的研究逐渐被揭示,在研究中所用材料大部分都是加害者(当事人)和受害者的口述史,缺乏日本军当时实施细菌战后对被害地的全面详细的疫学调查。731部队细菌战研究人员金子顺一论文《鼠疫效果略算法》,揭示了1940年农安、新京鼠疫流行事件是731部队实施的细菌战的事实。《陆军军医学校防疫研究报告第2部》中的高桥正彦论文中关于农安、新京鼠疫流行事件的论文,是731部队细菌战后对被害地进行的疫学调查。达格威文件Q报告中的部分数据来自“农安细菌战”受害者的病理解剖,其中不仅有中国人,也有日本人。%Facts about bacteriological warfare conducted by Japanese Army in China have been gradually re-vealed by related Chinese and Japanese researchers. However, the majority of materials used in the research are oral history orally accounted by offenders and victims, hence the lack of epidemic prevention surveys on the inflicted areas of bacteriological warfare by Japanese army. The thesis paper by Jun-Ichi Kaneko (bacterial warfare researcher of U-nit 731) namedBubonicPlagueAlgorithmunveiled the fact that plague epidemics which struck Nong’an and Changchun were caused by the Unit 731’s bacteriological warfare. Takahashi’s thesis paper inArmyMedicalCol-legeEpidemicPreventionResearchReport(VolumeⅡ)on plague epidemics that hit Nong’an and Changchun is in connection with the epidemic prevention surveys on the inflicted areas of bacteriological warfare carried out by the U-nit 731. Some data of the Report of“Q”from Dugway Proving Ground Documents came from pathological anatomy of victims of Nong’an bacteriological warfare, some of whom were Chinese and Japanese.

  19. Evaluation of chloropentafluorobenzene as an intake simulant for chemical defense training. Final report, October 1991-October 1992

    Energy Technology Data Exchange (ETDEWEB)

    Clewell, H.J.; Jarnot, B.M.


    For a number of years the U.S. Air Force has been performing research to develop safe intake simulants for chemical warfare agents (CWA) to provide accurate and quantitative real-time assessment of troop proficiency and gear efficacy during chemical warfare (CW) field exercises. Chloropentafluorobenzene (CPFB) was identified and evaluated as a candidate inhalation simulant, and was determined to possess desirable physiochemical and toxicological properties. These include rapid uptake, low metabolism and toxicity, rapid and predictable clearance, real-time detectability by existing portable 'breathalyzer' technology and by fielded CWA detectors, realistic canister breakthrough and commercial availability. A physiologically based pharmacokinetic (PBPK) model for CPEB has been developed which accurately describes the time course of blood and exhaled air concentrations during and following inhalation exposures of rats and primates to CPFB. This model has been employed to predict human exhaled air concentrations for several hours following brief CPFB exposures, such as might be experienced in training exercises using CPFB as an intake simulant. These simulants could be used to determine the exhaled air concentrations at which personnel would have been incapacitated had the exposure been to a real agent. The PBPK model was also used to calculate internal dose measures for a quantitative assessment of safe exposure criteria for the use of CPFB in such exercises. To assure the safety of personnel it is recommended that field exercises be designed to avoid exposures greater than 30 parts per million (ppm), with the daily (8 h) time-weighted average not to exceed 3 ppm. The exposure guideline should not impair use of CPFB since field analytical methods can measure CPFB.

  20. Groundwater geochemical and selected volatile organic compound data, Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington, June 2011 (United States)

    Huffman, Raegan L.; Frans, L.M.


    Previous investigations indicate that concentrations of chlorinated volatile organic compounds are substantial in groundwater beneath the 9-acre former landfill at Operable Unit 1, Naval Undersea Warfare Center, Division Keyport, Washington. Phytoremediation combined with ongoing natural attenuation processes was the preferred remedy selected by the U.S. Navy, as specified in the Record of Decision for the site. The U.S. Navy planted two hybrid poplar plantations on the landfill in spring 1999 to remove and to control the migration of chlorinated volatile organic compounds in shallow groundwater. The U.S. Geological Survey has continued to monitor groundwater geochemistry to ensure that conditions remain favorable for contaminant biodegradation as specified in the Record of Decision. This report presents groundwater geochemical and selected volatile organic compound data collected at Operable Unit 1 by the U.S. Geological Survey during June 20-22, 2011, in support of long-term monitoring for natural attenuation. In 2011, groundwater samples were collected from 13 wells and 9 piezometers. Samples from all wells and piezometers were analyzed for redox sensitive constituents and dissolved gases, and samples from 5 of 13 wells and all piezometers also were analyzed for chlorinated volatile organic compounds. Concentrations of redox sensitive constituents measured in 2011 were consistent with previous years, with dissolved oxygen concentrations all at 0.4 milligram per liter or less; little to no detectable nitrate; abundant dissolved manganese, iron, and methane; and commonly detected sulfide. The reductive declorination byproducts - methane, ethane, and ethene - were either not detected in samples collected from the upgradient wells in the landfill and the upper aquifer beneath the northern phytoremediation plantation or were detected at concentrations less than those measured in 2010. Chlorinated volatile organic compound concentrations in 2011 at most piezometers

  1. Toward improved software security training using a cyber warfare opposing force (CW OPFOR): the knowledge base design (United States)

    Stytz, Martin R.; Banks, Sheila B.


    "Train the way you will fight" has been a guiding principle for military training and has served the warfighter well as evidenced by numerous successful operations over the last decade. This need for realistic training for all combatants has been recognized and proven by the warfighter and continues to guide military training. However, to date, this key training principle has not been applied fully in the arena of cyberwarfare due to the lack of realistic, cost effective, reasonable, and formidable cyberwarfare opponents. Recent technological advances, improvements in the capability of computer-generated forces (CGFs) to emulate human behavior, and current results in research in information assurance and software protection, coupled with increasing dependence upon information superiority, indicate that the cyberbattlespace will be a key aspect of future conflict and that it is time to address the cyberwarfare training shortfall. To address the need for a cyberwarfare training and defensive testing capability, we propose research and development to yield a prototype computerized, semi-autonomous (SAF) red team capability. We term this capability the Cyber Warfare Opposing Force (CW OPFOR). There are several technologies that are now mature enough to enable, for the first time, the development of this powerful, effective, high fidelity CW OPFOR. These include improved knowledge about cyberwarfare attack and defense, improved techniques for assembling CGFs, improved techniques for capturing and expressing knowledge, software technologies that permit effective rapid prototyping to be effectively used on large projects, and the capability for effective hybrid reasoning systems. Our development approach for the CW OPFOR lays out several phases in order to address these requirements in an orderly manner and to enable us to test the capabilities of the CW OPFOR and exploit them as they are developed. We have completed the first phase of the research project, which

  2. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A


    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series presents contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study o

  3. Advances in chemical Physics

    CERN Document Server

    Rice, Stuart A


    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series offers contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study of che

  4. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A


    Advances in Chemical Physics is the only series of volumes available that explores the cutting edge of research in chemical physics. This is the only series of volumes available that presents the cutting edge of research in chemical physics.Includes contributions from experts in this field of research.Contains a representative cross-section of research that questions established thinking on chemical solutions.Structured with an editorial framework that makes the book an excellent supplement to an advanced graduate class in physical chemistry or chemical physics.

  5. Advances in chemical physics

    CERN Document Server

    Rice, Stuart A


    The Advances in Chemical Physics series-the cutting edge of research in chemical physics The Advances in Chemical Physics series provides the chemical physics and physical chemistry fields with a forum for critical, authoritative evaluations of advances in every area of the discipline. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series offers contributions from internationally renowned chemists and serves as the perfect supplement to any advanced graduate class devoted to the study of che

  6. Changing Face of Warfare (United States)


    work, Operations of War, stressed the importance of the offensive to the " suicidal in the defender.Ŝ Hamley’s work became a text at West Point in...Sanders attended the University of Georgia during the academic year of 1857·1858. He applied for, passed the required entrance exam and was...however, the acceptance of the offensive was stressed . 5 Perry D. Jamieson, Crossing the Deadly Ground: United States Army Tactics, 1865-1899

  7. Sustaining Unconventional Warfare (United States)


    establishment of a similar organization, the Special Project Operations Center ( SPOC ). SPOC adopted SOE’s practice of consolidating requirements and...That success depended largely on coordination between SFHQ personnel and a multitude of conventional force units. SPOC provided a unique capability

  8. Cyber warfare: critical perspectives

    NARCIS (Netherlands)

    Ducheine, P.; Osinga, F.; Soeters, J.


    Next to sea, land, air and space, ‘cyber space’ appears to be the fifth operational domain for the military. This manmade and virtual sphere brings along opportunities and threats. In this book, academics of the Netherlands Defence Academy as well as specialists and military professionals from other

  9. Unconventional Warfare in Cyberspace (United States)


    and social networking sites , including Facebook, he reached thousands.31 Al Qaeda’s 15 contact with possible recruits was done personally in three years. DARPA noted that operations are rapidly changing with the spread of blogs, social networking sites , and media-sharing technology

  10. Dehumanization and Irregular Warfare (United States)


    severe distrust between the locals and U.S. troops in the area. To rebuild trust, Bell promulgated a new policy for his officers that opposed carte ...and resulted in the assassination of the Indian Prime Minister, Indira Gandhi , in retaliation for Operation Blue Star. The shift in tactics

  11. Advanced Undersea Warfare Systems (United States)


    Barracuda ) Lightweight Torpedo." 6 May 2010. 1 May 2011 < 50 ( Barracuda ) Lightweight Torpedo." 6 May 2010. 1 May 2011 < docId

  12. Preventing Space Warfare

    Institute of Scientific and Technical Information of China (English)


    The international community should join forces to avoid possible conflicts in space Military competition and conflict in outer space can be divided into three stages:militarization,wea- ponization and the space battle- field. Space militarization has become a thing of the past.Now,many countries are re- searching more advanced space weaponry technology,which means space weapon- ization is becoming a growing reality.The process of space competition is astonishingly

  13. Air Power and Warfare (United States)


    Memorial, 1963. (T) 767.8 A3 ser .3, V.4) Air war against Germany and Italy, 1939-1943. Canberra: Australian War Memorial, 1954. (D 767.8 A3 Ser .3, al. Air poder indivisible Air University Ouarterly Review 2:5-18, Fall 1950. Spaatz, Crrl. Air-power odds against us. Readers Digest 58:11-14, June

  14. Countermobilization: Unconventional Social Warfare (United States)


    and solidarity in sustained interactions with elites, opponents and authorities.” 2 Social movements can encompass broad objectives such as...instructed to locally screen all personnel associated with SOI. Additionally, SOI personnel took oaths and were recorded into biometric databases

  15. On Winter Warfare (United States)


    in Latin (Puffendorf zen water bodies had been recognized long before Charles. 1685: Historia Germanico-Sveviae), are authoritative and The Mongols...declaration of war and crossing of the Roma - in the theater of operations, the armies on both sides suf- nian border on 24 April 1877. The war was

  16. Warfare and Social Theory

    DEFF Research Database (Denmark)

    Kaspersen, Lars Bo


    -related symptoms. METHODS: Cross-sectional studies were carried out in 1994, 2000 and 2005. The study population included men and women from ages 25 to 44 years (n (1994) = 1,781, n (2000) = 5,819, n (2005) = 4,831). The surveys were conducted by face-to-face interviews and the outcome measure was OTCA use...

  17. Chemical bond fundamental aspects of chemical bonding

    CERN Document Server

    Frenking, Gernot


    This is the perfect complement to ""Chemical Bonding - Across the Periodic Table"" by the same editors, who are two of the top scientists working on this topic, each with extensive experience and important connections within the community. The resulting book is a unique overview of the different approaches used for describing a chemical bond, including molecular-orbital based, valence-bond based, ELF, AIM and density-functional based methods. It takes into account the many developments that have taken place in the field over the past few decades due to the rapid advances in quantum chemica

  18. Intelligent Evaluation for Aerial Warfare Efficiency of Fighter-plane Based on Rough Set and Support Vector Machine%粗集支持向量机的战斗机空战效能智能评估

    Institute of Scientific and Technical Information of China (English)

    龚胜科; 徐浩军; 林敏


    根据现代空战特点,选取了战斗机的空战效能评估指标集,并采用粗糙集理论对指标体系进行约简,提取对空战效能影响起关键作用的特征参数,消除冗余信息,减少了支持向量的维效.支持向量机( SVM)具有结构简单、全局最优、泛化能力强的优点.根据所提取的特征参数,文中提出采用回归型支持向量机(SVR)建立空战效能智能评估模型,并通过实例与指数法和BP神经网络法计算结果进行了比较,验证了该模型的可行性和有效性.%According to the characteristic of modern aerial warfare. the index set of aerial warfare efficiency evaluation is selected in this paper. Reduction is performed on index systems based on rough set theory to extract characteristic parameters which affect aerial warfare efficiency crucially, which is to remove redundant information and reduce the dimension of support vector. Support vector machine (SVM) has the advantages of simple structure, global optimum and high generalization ability. With the characteristic parameters, intelligent evaluation model for aerial warfare efficiency of fighter-plane is establish by using Support Vector Regression (SVR), and we compare the SVR with index method and BP network method by a case study, which verified the feasibility and validity of the model.

  19. Analysis on Joint Operational Capability in the Condition of Information and Psychological Warfares%信息心理对抗条件下联合作战能力分析

    Institute of Scientific and Technical Information of China (English)

    闫家传; 秦伟; 陈璐; 张仁友


    In the information age, operational capabilities of troops include firepower, defense power, maintainance power, information power and many other factors, and the warfares between the opponents represent force confrontation, psychological confrontation, information warfares and many other complex forms. Based on the quantity analysis of joint operational capability, mutual functional mechanism of information, psychology and combat power is analyzed, and three feedback loops of operational confrontation, information warfares and psychological warfares are educed, and then system dynamical models are established, and effects on joint operational capability by information, psychology and other factors are deduced in the prospect of quantity.%信息化条件下作战,部队的作战能力表现为包括火力、防护力、保障力、信息力等多种因素的联合作战能力,作战双方的对抗表现为兵力对抗,心理对抗,信息对抗等多种复杂的形式.在联合作战能力量化分析基础上,分析了信息、心理和战斗力相互作用机制,得出了战斗对抗、信息对抗、心理对抗3个反馈回路环,并据此建立了系统动力学模型,从定量的角度分析了信息、心理等因素对联合作战能力的影响.

  20. Framework of Shipboard UAV Coordinated Surface to Sea Attack Based on Target-Centric Warfare Theory%基于目标中心战的舰载UAV协同对海突击作战构想

    Institute of Scientific and Technical Information of China (English)

    韩玉龙; 严建钢; 陈榕


    Aiming at the characteristics of shipboard UAV formationcoordinated surface to sea attack,absorbing target-centric warfare theory,a framework of shipboard UAV formationcoordinated surface to sea attack is put forward and the application feasibility of the theory is demonstrated. Then the conception and characteristics of shipboard UAV formationcoordinated surface to sea attack based on target-centric warfare theory are advanced. Moreover,this paper reconstructs the’Reconnaissance-Regulation-Attack-Evaluation’operation flow of target-centric warfare theory and establishes five steps for shipboard UAV coordinated surface to sea attack based on target-centric warfare theory, including situation evaluation, target selection and allocation, path planning and effectiveness evaluation.%针对舰载无人机编队协同对海突击作战的特点,在充分吸收目标中心战理论的基础上,提出了基于目标中心战的舰载无人机编队协同对海突击作战构想,论证了目标中心战应用于舰载无人机编队协同对海突击作战的可行性,并对其概念和特征进行了界定和分析,着重对目标中心战理论中的“侦-控-打-评”作战过程进行适应性改造,提出了基于目标中心战的舰载无人机编队协同对海突击作战的主要环节,包括态势评估,目标选择与分配,航路规划,协同打击和效能评估等。