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Sample records for chemical engineering problems

  1. Book of abstracts Chemical Engineering: IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists. Chemical engineering of nanomaterials. Energy- and resource-saving chemical-engineering processes and problems of their intensification. Processes and apparatuses of chemical engineering, chemical cybernetics. Ecological problems of chemical engineering and related fields

    International Nuclear Information System (INIS)

    Zakhodyaeva, Yu.A.; Belova, V.V.

    2012-01-01

    In the given volume of abstracts of the IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists (Moscow, March 18-23, 2012) there are the abstracts of the reports concerning chemical engineering of nanomaterials, energy- and resource-saving chemical-engineering processes, processes and apparatuses of chemical engineering, chemical cybernetics, ecological problems of chemical engineering and related fields. The abstracts deal with state-of-the-art and future development of theoretical and experimental investigations as well as with experience in practical realization of development works in the field of chemical engineering and relative areas [ru

  2. Problem-based learning biotechnology courses in chemical engineering.

    Science.gov (United States)

    Glatz, Charles E; Gonzalez, Ramon; Huba, Mary E; Mallapragada, Surya K; Narasimhan, Balaji; Reilly, Peter J; Saunders, Kevin P; Shanks, Jacqueline V

    2006-01-01

    We have developed a series of upper undergraduate/graduate lecture and laboratory courses on biotechnological topics to supplement existing biochemical engineering, bioseparations, and biomedical engineering lecture courses. The laboratory courses are based on problem-based learning techniques, featuring two- and three-person teams, journaling, and performance rubrics for guidance and assessment. Participants initially have found them to be difficult, since they had little experience with problem-based learning. To increase enrollment, we are combining the laboratory courses into 2-credit groupings and allowing students to substitute one of them for the second of our 2-credit chemical engineering unit operations laboratory courses.

  3. Class and Home Problems: Humidification, a True "Home" Problem for p. Chemical Engineer

    Science.gov (United States)

    Condoret, Jean-Stephane

    2012-01-01

    The problem of maintaining hygrothermal comfort in a house is addressed using the chemical engineer's toolbox. A simple dynamic modelling proved to give a good description of the humidification of the house in winter, using a domestic humidifier. Parameters of the model were identified from a simple experiment. Surprising results, especially…

  4. Teaching and Learning in Chemical Product Engineering - an Evolving par of the Chemical Engineering Curriculum

    DEFF Research Database (Denmark)

    Vigild, Martin Etchells; Kiil, Søren; Wesselingh, Johannes

    2007-01-01

    Over the last decade Chemical Product Engineering has evolved as part of the Chemical Engineering Curriculum at several universities in Europe and America. At the DTU Chemical Product Engineering was introduced in 2000. This presentation will report on the experiences gained from teaching classes...... and preparing a text book on the subject. [1] Chemical Product Engineering is solidly based on chemical technical and engineering knowledge. Furthermore, the subject naturally calls for a holistic approach to teaching and learning and introduces elements which target transferable and professional engineering...... skills. Such skills are important in Chemical Product Engineering when dealing with open-ended problems, creative problem solutions, operating in a team working environment and exercising project management. In our course we emphasise team activites, formative feed back to the students as well as helping...

  5. Chemical engineering side of nuclear fusion power

    International Nuclear Information System (INIS)

    Johnson, E.F.

    1976-10-01

    It is widely recognized that chemical engineering has important roles to play in the development of national and world wide energy resources through optimal utilization of fossil fuel reserves. It is much less appreciated that there are crucial chemical engineering problems in the development of energy production from other sources. In particular the successful development of nuclear fusion power generating systems will require the solution of many problems that are uniquely suited to chemical engineers. This article presents a brief overview of the fusion development program and an identification of the major technological problems remaining to be solved

  6. Chemical engineering problems of radioactive waste fixation by vitrification

    International Nuclear Information System (INIS)

    Taylor, R.F.

    1985-01-01

    Basic features are reviewed of the chemical engineering problems faced in the vitrification of the high-level radioactive liquid wastes resulting from the reprocessing of nuclear fuel. After an outline of glass solution properties and formation kinetics the constituent elements of the vitrification route are examined in turn: waste feed evaporation and denitration, calcination, offgas treatment, and finally melting and product quality. Plant and experimental data for each stage are discussed with comparison between process routes and with reference to the underlying principles. Attention is drawn to the future need for higher trapping efficiencies and for dealing with a wider range of species in offgas treatments as higher burnup fuels are processed after shorter cooling times from reactor. Two areas of present study where deeper insight into underlying process mechanics is needed are, firstly, the association of waste material with glass formers in the wet or sinter stages and secondly their incorporation and mixing reaction in the melt. Fuller understanding here would bring direct benefit to process performance and handling. The problems discussed are not of a nature to jeopardize the vitrification routes but if product quality does come to rely heavily on process control then demonstrable confidence in the behaviour of the central physico-chemical interactions is indispensable. (author)

  7. Mystery Well: Chemical-Engineering Solution to the Internal Rain Problem.

    Czech Academy of Sciences Publication Activity Database

    Růžička, Marek

    2017-01-01

    Roč. 174, DEC 31 (2017), s. 396-402 ISSN 0009-2509 Institutional support: RVO:67985858 Keywords : precipitation * humidity-driven convection * buoyant instability Subject RIV: CI - Industrial Chemistry, Chemical Engineering OBOR OECD: Chemical process engineering Impact factor: 2.895, year: 2016

  8. Computational problems in science and engineering

    CERN Document Server

    Bulucea, Aida; Tsekouras, George

    2015-01-01

    This book provides readers with modern computational techniques for solving variety of problems from electrical, mechanical, civil and chemical engineering. Mathematical methods are presented in a unified manner, so they can be applied consistently to problems in applied electromagnetics, strength of materials, fluid mechanics, heat and mass transfer, environmental engineering, biomedical engineering, signal processing, automatic control and more.

  9. Computational problems in engineering

    CERN Document Server

    Mladenov, Valeri

    2014-01-01

    This book provides readers with modern computational techniques for solving variety of problems from electrical, mechanical, civil and chemical engineering. Mathematical methods are presented in a unified manner, so they can be applied consistently to problems in applied electromagnetics, strength of materials, fluid mechanics, heat and mass transfer, environmental engineering, biomedical engineering, signal processing, automatic control and more.   • Features contributions from distinguished researchers on significant aspects of current numerical methods and computational mathematics; • Presents actual results and innovative methods that provide numerical solutions, while minimizing computing times; • Includes new and advanced methods and modern variations of known techniques that can solve difficult scientific problems efficiently.  

  10. Applied chemical engineering thermodynamics

    CERN Document Server

    Tassios, Dimitrios P

    1993-01-01

    Applied Chemical Engineering Thermodynamics provides the undergraduate and graduate student of chemical engineering with the basic knowledge, the methodology and the references he needs to apply it in industrial practice. Thus, in addition to the classical topics of the laws of thermodynamics,pure component and mixture thermodynamic properties as well as phase and chemical equilibria the reader will find: - history of thermodynamics - energy conservation - internmolecular forces and molecular thermodynamics - cubic equations of state - statistical mechanics. A great number of calculated problems with solutions and an appendix with numerous tables of numbers of practical importance are extremely helpful for applied calculations. The computer programs on the included disk help the student to become familiar with the typical methods used in industry for volumetric and vapor-liquid equilibria calculations.

  11. Introductory Level Problems Illustrating Concepts in Pharmaceutical Engineering

    Science.gov (United States)

    McIver, Keith; Whitaker, Kathryn; De Delva, Vladimir; Farrell, Stephanie; Savelski, Mariano J.; Slater, C. Stewart

    2012-01-01

    Textbook style problems including detailed solutions introducing pharmaceutical topics at the level of an introductory chemical engineering course have been created. The problems illustrate and teach subjects which students would learn if they were to pursue a career in pharmaceutical engineering, including the unique terminology of the field,…

  12. Book of abstracts Chemical Engineering: IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists. Engineering of polymers and composite materials. Catalysis in chemical engineering

    International Nuclear Information System (INIS)

    Zakhodyaeva, Yu.A.; Belova, V.V.

    2012-01-01

    In the given volume of abstracts of the IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists (Moscow, March 18-23, 2012) there are the abstracts of the reports concerning polymer and composite materials technology as well as catalysis in chemical engineering. The abstracts deal with state-of-the-art and future development of theoretical and experimental investigations as well as with experience in practical realization of development works in the field of chemical engineering and relative areas [ru

  13. Introducing DAE Systems in Undergraduate and Graduate Chemical Engineering Curriculum

    Science.gov (United States)

    Mandela, Ravi Kumar; Sridhar, L. N.; Rengaswamy, Raghunathan

    2010-01-01

    Models play an important role in understanding chemical engineering systems. While differential equation models are taught in standard modeling and control courses, Differential Algebraic Equation (DAE) system models are not usually introduced. These models appear naturally in several chemical engineering problems. In this paper, the introduction…

  14. Chemical engineering aspects in medicine

    Energy Technology Data Exchange (ETDEWEB)

    Chmiel, H

    1981-04-01

    Many basic chemical engineering processes are based on transport processes due, for example, to differences in temperature, pressure, and concentration. Such transport processes abound in the healthy circulatory system. Thus, metabolic processes supply the human body with the necessary warmth. The heart serves as a blood pump to provide optimal blood pressure in all vessels. Highly complex membranes in the kidneys ensure the efficient detoxification of the blood. It is therefore natural that the chemical engineer be involved in the solution of a number of biomedical engineering problems that come up in the field of medicine. Some typical tasks are: the characterization of the flow properties of biological fluids; research on the interaction between blood and foreign substances of the purpose of finding materials suitable for temporary or permanent use in the body and the development of blood pumps and artifical substitutes for the lungs, the liver, and the kidneys.

  15. Optimal control for chemical engineers

    CERN Document Server

    Upreti, Simant Ranjan

    2013-01-01

    Optimal Control for Chemical Engineers gives a detailed treatment of optimal control theory that enables readers to formulate and solve optimal control problems. With a strong emphasis on problem solving, the book provides all the necessary mathematical analyses and derivations of important results, including multiplier theorems and Pontryagin's principle.The text begins by introducing various examples of optimal control, such as batch distillation and chemotherapy, and the basic concepts of optimal control, including functionals and differentials. It then analyzes the notion of optimality, de

  16. Book of abstracts Chemical Engineering: IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists. Organic substances and pharmaceuticals engineering. Petrochemistry and chemical processing of alternative feedstock

    International Nuclear Information System (INIS)

    Zakhodyaeva, Yu.A.; Belova, V.V.

    2012-01-01

    In the given volume of abstracts of the IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists (Moscow, March 18-23, 2012) there are the abstracts of the reports concerning organic substances and pharmaceuticals engineering, petrochemistry and chemical processing of alternative feedstock. The abstracts deal with state-of-the-art and future development of theoretical and experimental investigations as well as with experience in practical realization of development works in the field of chemical engineering and relative areas [ru

  17. Selecting the Best: Evolutionary Engineering of Chemical Production in Microbes

    DEFF Research Database (Denmark)

    Shepelin, Denis; Hansen, Anne Sofie Lærke; Lennen, Rebecca

    2018-01-01

    , we focus primarily on a more challenging problem-the use of evolutionary engineering for improving the production of chemicals in microbes directly. We describe recent developments in evolutionary engineering strategies, in general, and discuss, in detail, case studies where production of a chemical......Microbial cell factories have proven to be an economical means of production for many bulk, specialty, and fine chemical products. However, we still lack both a holistic understanding of organism physiology and the ability to predictively tune enzyme activities in vivo, thus slowing down rational...... engineering of industrially relevant strains. An alternative concept to rational engineering is to use evolution as the driving force to select for desired changes, an approach often described as evolutionary engineering. In evolutionary engineering, in vivo selections for a desired phenotype are combined...

  18. Book of abstracts Chemical Engineering: IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists. Plenary reports. Engineering of inorganic substances and materials

    International Nuclear Information System (INIS)

    Zakhodyaeva, Yu.A.; Belova, V.V.

    2012-01-01

    In the given volume of abstracts of the IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists (Moscow, March 18-23, 2012) there are the abstracts of the reports concerning chemical engineering of inorganic substances and materials. The abstracts deal with state-of-the-art and future development of theoretical and experimental investigations as well as with experience in practical realization of development works in the field of chemical engineering and relative areas [ru

  19. Special theory on chemical engineering

    International Nuclear Information System (INIS)

    1987-06-01

    This book give a special description about chemical engineering. The contents of this book are special technique for isolation on introduction and separation by membrane, biochemistry engineering, process system engineering, energy engineering, environment engineering, a high molecular new material, election material and research on surface property of catalyst. It has appendixes on history of transition on Korean chemical engineering text contents and history of the activity of Korea chemical engineering institute.

  20. A New Paradigm for Chemical Engineering?

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    evidence of this change comes from the jobs taken by graduating chemical engineering professionals in North America, Europe, and some of the Asian countries. In terms of where the graduating chemical engineers are going to work, a clear shift from the commodity chemical industry to the product oriented...... businesses has been observed. There is an increasing trend within the chemical industry to focus on products and the sustainable processes that can make them. Do these changes point to a paradigm shift in chemical engineering as a discipline? Historically, two previous paradigm shifts in chemical engineering...... corresponded to major shifts in chemical engineering as a discipline, which affected not only the education of chemical engineers, but also the development of chemical engineering as a discipline. Has the time come for a new paradigm shift that will prepare the current and future chemical engineering graduates...

  1. Discussion on the Development of Green Chemistry and Chemical Engineering

    Science.gov (United States)

    Zhang, Yunshen

    2017-11-01

    Chemical industry plays a vital role in the development process of national economy. However, in view of the special nature of the chemical industry, a large number of poisonous and harmful substances pose a great threat to the ecological environment and human health in the entire process of raw material acquisition, production, transportation, product manufacturing, and the final practical application. Therefore, it is a general trend to promote the development of chemistry and chemical engineering towards a greener environment. This article will focus on some basic problems occurred in the development process of green chemistry and chemical engineering.

  2. Chemical Engineering Students: A Distinct Group among Engineers

    Science.gov (United States)

    Godwin, Allison; Potvin, Geoff

    2013-01-01

    This paper explores differences between chemical engineering students and students of other engineering disciplines, as identified by their intended college major. The data used in this analysis was taken from the nationally representative Sustainability and Gender in Engineering (SaGE) survey. Chemical engineering students differ significantly…

  3. Nuclear chemical engineering

    International Nuclear Information System (INIS)

    Lee, Geon Jae; Shin, Young Jun

    1989-08-01

    The contents of this book are introduction of chemical engineering and related chemistry on an atomic reactor, foundation of the chemistry nuclear chemical engineering, theory on nuclear engineering, the cycle of uranium and nuclear fuel, a product of nuclear division, nuclear reprocessing, management of spent fuel separation of radioisotope, materials of an atomic reactor, technology and chemistry related water in atomic reactors and utilization of radioisotope and radiation. This book has the exercises and reference books for the each chapter.

  4. 2002 Chemical Engineering Division annual report

    International Nuclear Information System (INIS)

    Lewis, D.; Graziano, D.; Miller, J. F.

    2003-01-01

    The Chemical Engineering Division is one of eight engineering research divisions within Argonne National Laboratory, one of the U.S. government's oldest and largest research laboratories. The University of Chicago oversees the laboratory on behalf of the U.S. Department of Energy (DOE). Argonne's mission is to conduct basic scientific research, to operate national scientific facilities, to enhance the nation's energy resources, and to develop better ways to manage environmental problems. Argonne has the further responsibility of strengthening the nation's technology base by developing innovative technology and transferring it to industry. The Division is a diverse early-stage engineering organization, specializing in the treatment of spent nuclear fuel, development of advanced electrochemical power sources, and management of both high- and low-level nuclear wastes. Although this work is often indistinguishable from basic research, our efforts are directed toward the practical devices and processes that are covered by Argonne's mission. Additionally, the Division operates the Analytical Chemistry Laboratory; Environment, Safety, and Health Analytical Chemistry services; and Dosimetry and Radioprotection services, which provide a broad range of analytical services to Argonne and other organizations. The Division is multidisciplinary. Its people have formal training as ceramists; physicists; material scientists; electrical, mechanical, chemical, and nuclear engineers; and chemists. They have experience working in academia; urban planning; and the petroleum, aluminum, and automotive industries. Their skills include catalysis, ceramics, electrochemistry, metallurgy, nuclear magnetic resonance spectroscopy, and petroleum refining, as well as the development of nuclear waste forms, batteries, and high-temperature superconductors. Our wide-ranging expertise finds ready application in solving energy and environmental problems. Division personnel are frequently called on by

  5. Chemical Engineering in the "BIO" world

    DEFF Research Database (Denmark)

    Chiarappa, Gianluca; Grassi, Mario; Abrami, Michela

    2017-01-01

    Modern Chemical Engineering was born around the end of the 19th century in Great Britain, Germany, and the USA, the most industrialized countries at that time. Milton C. Whitaker, in 1914, affirmed that the difference between Chemistry and Chemical Engineering lies in the capability of chemical...... engineers to transfer laboratory findings to the industrial level. Since then, Chemical Engineering underwent huge transformations determining the detachment from the original Chemistry nest. The beginning of the sixties of the 20th century saw the development of a new branch of Chemical Engineering...... baptized Biomedical Engineering by Peppas and Langer and that now we can name Biological Engineering. Interestingly, although Biological Engineering focused on completely different topics from Chemical Engineering ones, it resorted to the same theoretical tools such as, for instance, mass, energy...

  6. Applications of synchrotron radiation to Chemical Engineering Science: Workshop report

    International Nuclear Information System (INIS)

    1991-07-01

    This report contains extended abstracts that summarize presentations made at the Workshop on Applications of Synchrotron Radiation to Chemical Engineering Science held at Argonne National Laboratory (ANL), Argonne, IL, on April 22--23, 1991. The talks emphasized the application of techniques involving absorption fluorescence, diffraction, and reflection of synchrotron x-rays, with a focus on problems in applied chemistry and chemical engineering, as well as on the use of x-rays in topographic, tomographic, and lithographic procedures. The attendees at the workshop included experts in the field of synchrotron science, scientists and engineers from ANL, other national laboratories, industry, and universities; and graduate and undergraduate students who were enrolled in ANL educational programs at the time of the workshop. Talks in the Plenary and Overview Session described the status of and special capabilities to be offered by the Advanced Photon Source (APS), as well as strategies and opportunities for utilization of synchrotron radiation to solve science and engineering problems. Invited talks given in subsequent sessions covered the use of intense infrared, ultraviolet, and x-ray photon beams (as provided by synchrotrons) in traditional and nontraditional areas of chemical engineering research related to electrochemical and corrosion science, catalyst development and characterization, lithography and imaging techniques, and microanalysis

  7. Applications of synchrotron radiation to Chemical Engineering Science: Workshop report

    Energy Technology Data Exchange (ETDEWEB)

    1991-07-01

    This report contains extended abstracts that summarize presentations made at the Workshop on Applications of Synchrotron Radiation to Chemical Engineering Science held at Argonne National Laboratory (ANL), Argonne, IL, on April 22--23, 1991. The talks emphasized the application of techniques involving absorption fluorescence, diffraction, and reflection of synchrotron x-rays, with a focus on problems in applied chemistry and chemical engineering, as well as on the use of x-rays in topographic, tomographic, and lithographic procedures. The attendees at the workshop included experts in the field of synchrotron science, scientists and engineers from ANL, other national laboratories, industry, and universities; and graduate and undergraduate students who were enrolled in ANL educational programs at the time of the workshop. Talks in the Plenary and Overview Session described the status of and special capabilities to be offered by the Advanced Photon Source (APS), as well as strategies and opportunities for utilization of synchrotron radiation to solve science and engineering problems. Invited talks given in subsequent sessions covered the use of intense infrared, ultraviolet, and x-ray photon beams (as provided by synchrotrons) in traditional and nontraditional areas of chemical engineering research related to electrochemical and corrosion science, catalyst development and characterization, lithography and imaging techniques, and microanalysis.

  8. Nanotechnology for chemical engineers

    CERN Document Server

    Salaheldeen Elnashaie, Said; Hashemipour Rafsanjani, Hassan

    2015-01-01

    The book describes the basic principles of transforming nano-technology into nano-engineering with a particular focus on chemical engineering fundamentals. This book provides vital information about differences between descriptive technology and quantitative engineering for students as well as working professionals in various fields of nanotechnology. Besides chemical engineering principles, the fundamentals of nanotechnology are also covered along with detailed explanation of several specific nanoscale processes from chemical engineering point of view. This information is presented in form of practical examples and case studies that help the engineers and researchers to integrate the processes which can meet the commercial production. It is worth mentioning here that, the main challenge in nanostructure and nanodevices production is nowadays related to the economic point of view. The uniqueness of this book is a balance between important insights into the synthetic methods of nano-structures and nanomaterial...

  9. Introduction to chemical reaction engineering

    International Nuclear Information System (INIS)

    Kim, Yeong Geol

    1990-10-01

    This deals with chemical reaction engineering with thirteen chapters. The contents of this book are introduction on reaction engineering, chemical kinetics, thermodynamics and chemical reaction, abnormal reactor, non-isothermal reactor, nonideal reactor, catalysis in nonuniform system, diffusion and reaction in porosity catalyst, design catalyst heterogeneous reactor in solid bed, a high molecule polymerization, bio reaction engineering, reaction engineering in material process, control multi-variable reactor process using digital computer.

  10. Modern Cast Irons in Chemical Engineering

    Science.gov (United States)

    1934-11-09

    fl’ceew. T I SOCIETY OF CHEMICAL INDUSTRY CHEMICAL ENGINEERING GROUP MODERN CAST IRONS IN CHEMICAL ENGINEERING By J. G. PEARCE, M.Sc., F.Inst.P...CAST IRONS IN CHEMICAL ENGINEERING By J. G. PEARCE, M.Sc., F.Inst.P., M.I.E.E.* INTRODUCTION to chemical or thermal resistance. Small blow-holes Any...consideration of modern cast irons in chemical seldom appear to reduce the mechanical strength of engineering should strictly be prefaced by a definition

  11. Chemical Engineering in the "BIO" World.

    Science.gov (United States)

    Chiarappa, Gianluca; Grassi, Mario; Abrami, Michela; Abbiati, Roberto Andrea; Barba, Anna Angela; Boisen, Anja; Brucato, Valerio; Ghersi, Giulio; Caccavo, Diego; Cascone, Sara; Caserta, Sergio; Elvassore, Nicola; Giomo, Monica; Guido, Stefano; Lamberti, Gaetano; Larobina, Domenico; Manca, Davide; Marizza, Paolo; Tomaiuolo, Giovanna; Grassi, Gabriele

    2017-01-01

    Modern Chemical Engineering was born around the end of the 19th century in Great Britain, Germany, and the USA, the most industrialized countries at that time. Milton C. Whitaker, in 1914, affirmed that the difference between Chemistry and Chemical Engineering lies in the capability of chemical engineers to transfer laboratory findings to the industrial level. Since then, Chemical Engineering underwent huge transformations determining the detachment from the original Chemistry nest. The beginning of the sixties of the 20th century saw the development of a new branch of Chemical Engineering baptized Biomedical Engineering by Peppas and Langer and that now we can name Biological Engineering. Interestingly, although Biological Engineering focused on completely different topics from Chemical Engineering ones, it resorted to the same theoretical tools such as, for instance, mass, energy and momentum balances. Thus, the birth of Biological Engineering may be considered as a Darwinian evolution of Chemical Engineering similar to that experienced by mammals which, returning to water, used legs and arms to swim. From 1960 on, Biological Engineering underwent a considerable evolution as witnessed by the great variety of topics covered such as hemodialysis, release of synthetic drugs, artificial organs and, more recently, delivery of small interfering RNAs (siRNA). This review, based on the activities developed in the frame of our PRIN 2010-11 (20109PLMH2) project, tries to recount origins and evolution of Chemical Engineering illustrating several examples of recent and successful applications in the biological field. This, in turn, may stimulate the discussion about the Chemical Engineering students curriculum studiorum update. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  12. Selecting the Best: Evolutionary Engineering of Chemical Production in Microbes.

    Science.gov (United States)

    Shepelin, Denis; Hansen, Anne Sofie Lærke; Lennen, Rebecca; Luo, Hao; Herrgård, Markus J

    2018-05-11

    Microbial cell factories have proven to be an economical means of production for many bulk, specialty, and fine chemical products. However, we still lack both a holistic understanding of organism physiology and the ability to predictively tune enzyme activities in vivo, thus slowing down rational engineering of industrially relevant strains. An alternative concept to rational engineering is to use evolution as the driving force to select for desired changes, an approach often described as evolutionary engineering. In evolutionary engineering, in vivo selections for a desired phenotype are combined with either generation of spontaneous mutations or some form of targeted or random mutagenesis. Evolutionary engineering has been used to successfully engineer easily selectable phenotypes, such as utilization of a suboptimal nutrient source or tolerance to inhibitory substrates or products. In this review, we focus primarily on a more challenging problem-the use of evolutionary engineering for improving the production of chemicals in microbes directly. We describe recent developments in evolutionary engineering strategies, in general, and discuss, in detail, case studies where production of a chemical has been successfully achieved through evolutionary engineering by coupling production to cellular growth.

  13. The Chemical Engineering behind How Carbonated Beverages Go Flat: A Hands-On Experiment for Freshmen Students

    Science.gov (United States)

    Hohn, Keith L.

    2007-01-01

    A hands-on project was developed to educate new chemical engineering students about the types of problems chemical engineers solve and to improve student enthusiasm for studying chemical engineering. In this project, students studied the phenomenon of carbonated beverages going flat. The project was implemented in 2003 and 2004 at Kansas State…

  14. The large dictionary on chemical engineering

    International Nuclear Information System (INIS)

    1995-03-01

    This book mentions the large dictionary on chemical engineering. It starts the preface. It mentions introduction for publish committee. It also has signature of publish committee. It introduces explanatory notes. It gives descriptions of glossary on chemical engineering. This has appendixes and index. This book consists of seven part to explain chemical engineering glossary. It was written by chemical engineering dictionary publish committee.

  15. Chemical Engineering Education - Current and Future Trends

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    topics (transport phenomena, separations, reaction engineering, etc.) must remain strong, should the applications that currently emphasize commodity chemicals also include new topics such as sustainability, and product design? In Europe, the European Federation of Chemical Engineering (EFCE) has taken...... has a product focus. With this shift of the chemical industry, what should be the curriculum of the chemical engineering degrees at the BSc- and MSc-levels, and, are the skill set of chemical engineers appropriate for this altered chemical industry? While the basic skill set, defined by the core...... a leading role to define the chemical engineering curriculum. The result has been a set of recommendations for the first (BSc), second (MSc) and third (PhD) cycle chemical engineering education aligned to the Bologna Process. They recommend that students studying towards bachelor and masters qualifications...

  16. Argonne Chemical Sciences & Engineering - Awards Home

    Science.gov (United States)

    Argonne National Laboratory Chemical Sciences & Engineering DOE Logo CSE Home About CSE Argonne Home > Chemical Sciences & Engineering > Fundamental Interactions Catalysis & Energy Computational Postdoctoral Fellowships Contact Us CSE Intranet Awards Argonne's Chemical Sciences and

  17. Book of abstracts Chemical Engineering: IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists. Materials of All-Russian Symposium on chemistry and extraction engineering. Chemical-metallurgical processes of ore and secondary raw material processing. Analytical control of chemical industries, man-made and natural objects

    International Nuclear Information System (INIS)

    Zakhodyaeva, Yu.A.; Belova, V.V.

    2012-01-01

    In the given volume of abstracts of the IV All-Russian Conference on chemical engineering, All-Russian Youth Conference on chemical engineering, All-Russian school on chemical engineering for young scientists and specialists (Moscow, March 18-23, 2012) there are the abstracts of the reports concerning polymer and composite materials technology as well as catalysis in chemical engineering. The abstracts deal with state-of-the-art and future development of theoretical and experimental investigations as well as with experience in practical realization of development works in the field of chemical engineering and relative areas [ru

  18. Nuclear industry - challenges in chemical engineering

    International Nuclear Information System (INIS)

    Sen, S.; Sunder Rajan, N.S.; Balu, K.; Garg, R.K.; Murthy, L.G.K.; Ramani, M.P.S.; Rao, M.K.; Sadhukhan, H.K.; Venkat Raj, V.

    1978-01-01

    As chemical engineering processes and operations are closely involved in many areas of nuclear industry, the chemical engineer has a vital role to play in its growth and development. An account of the major achievements of the Indian chemical engineers in this field is given with view of impressing upon the faculty members of the Indian universities the need for taking appropriate steps to prepare chemical engineers suitable for nuclear industry. Some of the major achievements of the Indian chemical engineers in this field are : (1) separation of useful minerals from beach sand, (2) preparation of thorium nitrate of nuclear purity from monazite, (3) processing of zircon sand to obtain nuclear grade zirconium and its separation from hafnium to obtain zirconium metal sponge, (4) recovery of uranium from copper tailings, (5) economic recovery of nuclear grade uranium from low grade uranium ores found in India, (6) fuel reprocessing, (7) chemical processing of both low and high level radioactive wastes. (M.G.B.)

  19. Y2K of the society of chemical engineers, Japan; Kagaku kogakukai no 2000nen mondai

    Energy Technology Data Exchange (ETDEWEB)

    Kataoka, K. [Kobe University, Kobe (Japan)

    2000-01-05

    In this paper, the coming problem of the Y2K problems by the cataclysm of economic society that the Society of Chemical Engineers holds is described. And it is explained in dividing into the present problems for the development of the Society of Chemical Engineers, a science and technology promotion policy, a university/industry cooperation, a regional cooperation, an internationality and international contribution, an effect of an independent administrative corporation of national universities, the movement of a future plan, the terms of member needs and a base establishment. In the paragraph of the movement of a future plan, the facts that a basic philosophy of the Society of Chemical Engineers was suggested standing on the report of the Vision Settlement Preparation Committee organized in 1998, the Chemical Industry Vision 2011 Settlement Committee was inaugurated for constituting its future images and the Working Group composed of the members of the Industry Institute in their forties leading the next generation was established is introduced. (NEDO)

  20. Engineering chemical interactions in microbial communities.

    Science.gov (United States)

    Kenny, Douglas J; Balskus, Emily P

    2018-03-05

    Microbes living within host-associated microbial communities (microbiotas) rely on chemical communication to interact with surrounding organisms. These interactions serve many purposes, from supplying the multicellular host with nutrients to antagonizing invading pathogens, and breakdown of chemical signaling has potentially negative consequences for both the host and microbiota. Efforts to engineer microbes to take part in chemical interactions represent a promising strategy for modulating chemical signaling within these complex communities. In this review, we discuss prominent examples of chemical interactions found within host-associated microbial communities, with an emphasis on the plant-root microbiota and the intestinal microbiota of animals. We then highlight how an understanding of such interactions has guided efforts to engineer microbes to participate in chemical signaling in these habitats. We discuss engineering efforts in the context of chemical interactions that enable host colonization, promote host health, and exclude pathogens. Finally, we describe prominent challenges facing this field and propose new directions for future engineering efforts.

  1. Teaching Chemical Engineers about Teaching

    Science.gov (United States)

    Heath, Daniel E.; Hoy, Mary; Rathman, James F.; Rohdieck, Stephanie

    2013-01-01

    The Chemical and Biomolecular Engineering Department at The Ohio State University in collaboration with the University Center for the Advancement of Teaching developed the Chemical Engineering Mentored Teaching Experience. The Mentored Teaching Experience is an elective for Ph.D. students interested in pursuing faculty careers. Participants are…

  2. Protein engineering approaches to chemical biotechnology.

    Science.gov (United States)

    Chen, Zhen; Zeng, An-Ping

    2016-12-01

    Protein engineering for the improvement of properties of biocatalysts and for the generation of novel metabolic pathways plays more and more important roles in chemical biotechnology aiming at the production of chemicals from biomass. Although widely used in single-enzyme catalysis process, protein engineering is only being increasingly explored in recent years to achieve more complex in vitro and in vivo biocatalytic processes. This review focuses on major contributions of protein engineering to chemical biotechnology in the field of multi-enzymatic cascade catalysis and metabolic engineering. Especially, we discuss and highlight recent strategies for combining pathway design and protein engineering for the production of novel products. Copyright © 2016. Published by Elsevier Ltd.

  3. Chemical-text hybrid search engines.

    Science.gov (United States)

    Zhou, Yingyao; Zhou, Bin; Jiang, Shumei; King, Frederick J

    2010-01-01

    As the amount of chemical literature increases, it is critical that researchers be enabled to accurately locate documents related to a particular aspect of a given compound. Existing solutions, based on text and chemical search engines alone, suffer from the inclusion of "false negative" and "false positive" results, and cannot accommodate diverse repertoire of formats currently available for chemical documents. To address these concerns, we developed an approach called Entity-Canonical Keyword Indexing (ECKI), which converts a chemical entity embedded in a data source into its canonical keyword representation prior to being indexed by text search engines. We implemented ECKI using Microsoft Office SharePoint Server Search, and the resultant hybrid search engine not only supported complex mixed chemical and keyword queries but also was applied to both intranet and Internet environments. We envision that the adoption of ECKI will empower researchers to pose more complex search questions that were not readily attainable previously and to obtain answers at much improved speed and accuracy.

  4. Electrochemical energy engineering: a new frontier of chemical engineering innovation.

    Science.gov (United States)

    Gu, Shuang; Xu, Bingjun; Yan, Yushan

    2014-01-01

    One of the grand challenges facing humanity today is a safe, clean, and sustainable energy system where combustion no longer dominates. This review proposes that electrochemical energy conversion could set the foundation for such an energy system. It further suggests that a simple switch from an acid to a base membrane coupled with innovative cell designs may lead to a new era of affordable electrochemical devices, including fuel cells, electrolyzers, solar hydrogen generators, and redox flow batteries, for which recent progress is discussed using the authors' work as examples. It also notes that electrochemical energy engineering will likely become a vibrant subdiscipline of chemical engineering and a fertile ground for chemical engineering innovation. To realize this vision, it is necessary to incorporate fundamental electrochemistry and electrochemical engineering principles into the chemical engineering curriculum.

  5. Massachusetts Institute of Technology School of Chemical Engineering Practice, Brookhaven station: Summary of projects, 1983-1986

    International Nuclear Information System (INIS)

    1987-11-01

    The MIT Graduate School of Chemical Engineering Practice stresses engineering problem solving. The Practice School program, as it is commonly called, develops in a unique and particularly effective way the student's ability to apply fundamentals to problems in the chemical industry and thus accelerates one's professional development. The themes of atomization, emthanol production and utilization, hydrogen production and compression, localized electrochemical corrosion and biochemical engineering reflect some of the major programs at the Laboratory. The titles of all the projects are listed in chronological order in the index at the end of this document. Brief summaries are presented for each project with related projects grouped together

  6. Indian Chemical Engineering Congress 1995: 48th annual session of Indian Institute of Chemical Engineers: abstracts and invited lectures

    International Nuclear Information System (INIS)

    1995-01-01

    The 48th Annual Session of Indian Institute of Chemical Engineers was held in Kalpakkam during December 27-30, 1995. The book contains the proceeding of the conference, both abstracts and invited lectures. The topics covered included various aspects pertaining to chemical engineering and technology along with the chemical and engineering processes relevant to nuclear fuel cycle like uranium ore processing, fuel fabrication, reactor operation, fuel reprocessing and radioactive waste management. Papers relevant to INIS are indexed separately

  7. Problem Solving Methods in Engineering Design

    DEFF Research Database (Denmark)

    Hartvig, Susanne C

    1999-01-01

    This short paper discusses typical engineering tasks and problem solving methods, based on a field study of engineering tasks at a Danish engineering firm. The field study has identified ten classes of design tasks and in this paper these classes are related to problem solving methods. The descri...

  8. Progress in reforming chemical engineering education.

    Science.gov (United States)

    Wankat, Phillip C

    2013-01-01

    Three successful historical reforms of chemical engineering education were the triumph of chemical engineering over industrial chemistry, the engineering science revolution, and Engineering Criteria 2000. Current attempts to change teaching methods have relied heavily on dissemination of the results of engineering-education research that show superior student learning with active learning methods. Although slow dissemination of education research results is probably a contributing cause to the slowness of reform, two other causes are likely much more significant. First, teaching is the primary interest of only approximately one-half of engineering faculty. Second, the vast majority of engineering faculty have no training in teaching, but trained professors are on average better teachers. Significant progress in reform will occur if organizations with leverage-National Science Foundation, through CAREER grants, and the Engineering Accreditation Commission of ABET-use that leverage to require faculty to be trained in pedagogy.

  9. Conceptual Framework to Help Promote Retention and Transfer in the Introductory Chemical Engineering Course

    Science.gov (United States)

    Hanyak, Michael E., Jr.

    2015-01-01

    In an introductory chemical engineering course, the conceptual framework of a holistic problem-solving methodology in conjunction with a problem-based learning approach has been shown to create a learning environment that nurtures deep learning rather than surface learning. Based on exam scores, student grades are either the same or better than…

  10. Nuclear industry - challenges in chemical engineering

    International Nuclear Information System (INIS)

    Sen, S.; Sunder Rajan, N.S.; Balu, K.; Garg, R.K.; Murthy, L.G.K.; Ramani, M.P.S.; Rao, M.K.; Sadhukhan, H.K.; Venkat Raj, V.

    1978-01-01

    Chemical engineering processes and operations are closely involved in every step of the nuclear fuel cycle. Starting from mining and milling of the ore through the production of fuel and other materials and their use in nuclear reactors, fuel reprocessing, fissile material recycle and treatment and disposal of fission product wastes, each step presents a challenge to the chemical engineer to evolve and innovate processes and techniques for more efficient utilization of the energy in the atom. The requirement of high recovery of the desired components at high purity levels is in itself a challenge. ''Nuclear Grade'' specifications for materials put a requirement which very few industries can satisfy. Recovery of uranium and thorium from low grade ores, of heavy water from raw water, etc. are examples. Economical and large scale separation of isotopes particularly those of heavy elements is a task for which processess are under various stages of development. Further design of chemical plants such as fuel reprocessing plants and high level waste treatment plants, which are to be operated and maintained remotely due to the high levels of radio-activity call for engineering skills which are being continually evolved. In the reactor, analysis of the fluid mechanics and optimum design of heat removal system are other examples where a chemical engineer can play a useful role. In addition to the above, the activities in the nuclear industry cover a very wide range of chemical engineering applications, such as desalination and other energy intensive processes, radioisotope and radiation applications in industry, medicine and agriculture. (auth.)

  11. Molecular engineering problems in heat and mass transfer

    International Nuclear Information System (INIS)

    Kotake, S.

    1991-01-01

    As for developing, manufacturing and applying new materials of advanced functions such as high-performance devices and high-temperature materials, fundamental understanding of the phenomena from the standpoint of molecular and atomic levels has been required. In these problems, the processes of heat and mass transfer play an important role, being one of the rate-controlling factors. But the energy levels associated with heat and mass transfer are of the orders much less than those of chemical reaction, and it is not easy to understand the thermal problems on the molecular and atomic basis. This paper views the processes of heat and mass transfer from the dynamical motions of atom and molecule for thermal engineering problems. Especially, problems are considered of heat conduction in fine-ceramics, sintered materials of high heat conductivity or high heat-insulation, phase change of condensation in vapor deposition processes such as CVD and PVD, and radiation in laser processing

  12. Career Opportunities in Chemistry and Chemical Engineering.

    Science.gov (United States)

    Glover, Trienne

    This pamphlet discusses career and employment opportunities in chemical engineering. Necessary college preparation is described and median salaries by degree are tabulated. Nontraditional careers in chemistry are also described. Future demand for chemists and chemical engineers is projected to 1985 and the availability of jobs for women and…

  13. Design and analysis of questionnaires for survey skills in chemical engineering

    Directory of Open Access Journals (Sweden)

    Susana Lucas

    2011-09-01

    multidisciplinary teams and learn on one’s own accord, and to be aware of the need for life-long learning. Furthermore, students and teachers agreed that there is a direct correlation between the higher development of specific skills and the chemical engineering learning outcomes. In this sense, an important effort should be devoted to the development of a students´ transferable skills by way of modifying the current teaching-learning system (partial substitution of lectures with tutorials and seminars, strategies based on problem-solving, projects and case studies (individual or student team-work, use of internet and electronic tools, etc..

  14. Argonne Chemical Sciences & Engineering - Center for Electrical Energy

    Science.gov (United States)

    Laboratory Chemical Sciences & Engineering DOE Logo CSE Home About CSE Research Facilities People Publications Awards News & Highlights Events Search Argonne ... Search Argonne Home > Chemical Sciences & Engineering > Fundamental Interactions Catalysis & Energy Conversion Electrochemical

  15. Hafnium - material for chemical apparatus engineering

    International Nuclear Information System (INIS)

    Jennert, D.

    1981-01-01

    This work describes - on the background of available literature - the properties of hafnium in technical quality (DIN-material No. 2.6400) as material for chemical apparatus engineering. The occurence, refining, physical and chemical properties will be described as well as the material behavior. In conclusion, it has been found that there is, at present, sufficient information for the engineering of hafnium which has to be completed by additional investigations for special applications. (orig.) [de

  16. Heat Exchanger Lab for Chemical Engineering Undergraduates

    Science.gov (United States)

    Rajala, Jonathan W.; Evans, Edward A.; Chase, George G.

    2015-01-01

    Third year chemical engineering undergraduate students at The University of Akron designed and fabricated a heat exchanger for a stirred tank as part of a Chemical Engineering Laboratory course. The heat exchanger portion of this course was three weeks of the fifteen week long semester. Students applied concepts of scale-up and dimensional…

  17. Chemical Engineering at NASA

    Science.gov (United States)

    Collins, Jacob

    2008-01-01

    This viewgraph presentation is a review of the career paths for chemicals engineer at NASA (specifically NASA Johnson Space Center.) The author uses his personal experience and history as an example of the possible career options.

  18. Chemical Engineering in Space

    Science.gov (United States)

    Lobmeyer, Dennis A.; Meneghelli, Barry; Steinrock, Todd (Technical Monitor)

    2001-01-01

    The aerospace industry has long been perceived as the domain of both physicists and mechanical engineers. This perception has endured even though the primary method of providing the thrust necessary to launch a rocket into space is chemical in nature. The chemical engineering and chemistry personnel behind the systems that provide access to space have labored in the shadows of the physicists and mechanical engineers. As exploration into the cosmos moves farther away from Earth, there is a very distinct need for new chemical processes to help provide the means for advanced space exploration. The state of the art in launch systems uses chemical propulsion systems, primarily liquid hydrogen and liquid oxygen, to provide the energy necessary to achieve orbit. As we move away from Earth, there are additional options for propulsion. Unfortunately, few of these options can compare to the speed or ease of use provided by the chemical propulsion agents. It is with great care and significant cost that gaseous compounds such as hydrogen and oxygen are liquefied and become dense enough to use for rocket fuel. These low-temperature liquids fall within a specialty area known as cryogenics. Cryogenics, the science and art of producing cold operating conditions for use on Earth, in orbit, or on some other nonterrestrial body, has become increasingly important to our ability to travel within our solar system. The production of cryogenic fuels and the long-term storage of these fluids are necessary for travel. As our explorations move farther away from Earth, we need to address how to produce the necessary fuels to make a round-trip. The cost and the size of these expeditions are extreme at best. If we take everything necessary for our survival for the round-trip, we invalidate any chance of travel in the near future. As with the early explorers on Earth, we need to harvest much of our energy and our life support from the celestial bodies. The in situ production of these energy

  19. Techniques for Analysing Problems in Engineering Projects

    DEFF Research Database (Denmark)

    Thorsteinsson, Uffe

    1998-01-01

    Description of how CPM network can be used for analysing complex problems in engineering projects.......Description of how CPM network can be used for analysing complex problems in engineering projects....

  20. The thermodynamics of heat- and mass exchange in chemical engineering. Vol. 1. 2. rev. ed.

    International Nuclear Information System (INIS)

    Matz, G.

    1979-01-01

    The second and completely revised edition of the approved textbook 'The thermodynamics of heat- and mass exchange in chemical engineering' is devoted to students of technical and natural science disciplines as well as to practicians and scientists, which are confronted with thermodynamical problems of chemical engineering. Starting from the different phases and properties of matter, the first and the second law of thermodynamics are discussed together with many applications. After an introduction of the equilibrium state, the general principle of similarity for heat- and mass exchange is discussed, considering in particular the heat- and mass exchange in the counter flow between two phases. In a final chapter, the heat- and mass exchange between the vapor- and liquid phase is discussed, with special emphasis on problems as evaporation and drying. (orig./HK) [de

  1. Expert vs. novice: Problem decomposition/recomposition in engineering design

    Science.gov (United States)

    Song, Ting

    The purpose of this research was to investigate the differences of using problem decomposition and problem recomposition among dyads of engineering experts, dyads of engineering seniors, and dyads of engineering freshmen. Fifty participants took part in this study. Ten were engineering design experts, 20 were engineering seniors, and 20 were engineering freshmen. Participants worked in dyads to complete an engineering design challenge within an hour. The entire design process was video and audio recorded. After the design session, members participated in a group interview. This study used protocol analysis as the methodology. Video and audio data were transcribed, segmented, and coded. Two coding systems including the FBS ontology and "levels of the problem" were used in this study. A series of statistical techniques were used to analyze data. Interview data and participants' design sketches also worked as supplemental data to help answer the research questions. By analyzing the quantitative and qualitative data, it was found that students used less problem decomposition and problem recomposition than engineer experts in engineering design. This result implies that engineering education should place more importance on teaching problem decomposition and problem recomposition. Students were found to spend less cognitive effort when considering the problem as a whole and interactions between subsystems than engineer experts. In addition, students were also found to spend more cognitive effort when considering details of subsystems. These results showed that students tended to use dept-first decomposition and experts tended to use breadth-first decomposition in engineering design. The use of Function (F), Behavior (B), and Structure (S) among engineering experts, engineering seniors, and engineering freshmen was compared on three levels. Level 1 represents designers consider the problem as an integral whole, Level 2 represents designers consider interactions between

  2. Mini-projects in Chemical Engineering Laboratory

    Directory of Open Access Journals (Sweden)

    Angeles Cancela

    2013-03-01

    Full Text Available Chemical engineering laboratory practices based in mini-projects were design and applied the students of forestry engineering in chemical subject. This way of practice reveals a more cooperative learning and a different style of experimentation. The stated goal was to design practices that motivate students and to enable them to develop different skills, including cross teamwork and communication. This paper describes how these practices were developed and the advantages and disadvantages of using this methodology of teaching.

  3. Proceedings of 20. Symposium of Malaysian Chemical Engineers (SOMChE 2006)

    International Nuclear Information System (INIS)

    2006-12-01

    The objective of the symposium is to provide a platform for participants and relevant chemical engineering community to meet and encourage expertise and knowledge sharing and to allow recent chemical engineering research and innovation works to be properly documented, displayed and made known to interested parties. The subjects discussed are advanced material modeling and simulation bioprocess, catalysis, chemical engineering education (outcome-based education), computational fluid dynamics, drying technology, energy, environment, fine chemicals, food engineering, oil and gas, oleochemical, particle technology, petrochemical, pharmaceutical engineering, polymer technology, process control, process system, engineering, reaction engineering, renewable energy, separation

  4. Engineering microbes for efficient production of chemicals

    Science.gov (United States)

    Gong, Wei; Dole, Sudhanshu; Grabar, Tammy; Collard, Andrew Christopher; Pero, Janice G; Yocum, R Rogers

    2015-04-28

    This present invention relates to production of chemicals from microorganisms that have been genetically engineered and metabolically evolved. Improvements in chemical production have been established, and particular mutations that lead to those improvements have been identified. Specific examples are given in the identification of mutations that occurred during the metabolic evolution of a bacterial strain genetically engineered to produce succinic acid. This present invention also provides a method for evaluating the industrial applicability of mutations that were selected during the metabolic evolution for increased succinic acid production. This present invention further provides microorganisms engineered to have mutations that are selected during metabolic evolution and contribute to improved production of succinic acid, other organic acids and other chemicals of commercial interest.

  5. Problem Decomposition and Recomposition in Engineering Design: A Comparison of Design Behavior between Professional Engineers, Engineering Seniors, and Engineering Freshmen

    Science.gov (United States)

    Song, Ting; Becker, Kurt; Gero, John; DeBerard, Scott; DeBerard, Oenardi; Reeve, Edward

    2016-01-01

    The authors investigated the differences in using problem decomposition and problem recomposition between dyads of engineering experts, engineering seniors, and engineering freshmen. Participants worked in dyads to complete an engineering design challenge within 1 hour. The entire design process was video and audio recorded. After the design…

  6. 5th National meeting of the SA Institution of Chemical Engineers: chemical engineering in support of industry and society. V. 1-3

    International Nuclear Information System (INIS)

    1988-01-01

    The 5th national meeting of the SA Institution of Chemical Engineering was held from 15-16 August 1988 at Pretoria. The subject scope covered on the meeting include the broad spectrum of work done by the chemical engineer. The main categories include the processing of agricultural products, biotechnology, coal and hydrocarbons, the chemical engineering practice, fluid dynamics, gas treatment, heat and mass transfer, materials of construction, minerals processing, source materials and products, training and education, vapour-liquid equilibrium, and water and effluents. One seminar specifically covers process engineering in the context of nuclear reactors and two other papers cover supported liquid membrane extraction of uranium

  7. Mathematical modeling a chemical engineer's perspective

    CERN Document Server

    Rutherford, Aris

    1999-01-01

    Mathematical modeling is the art and craft of building a system of equations that is both sufficiently complex to do justice to physical reality and sufficiently simple to give real insight into the situation. Mathematical Modeling: A Chemical Engineer's Perspective provides an elementary introduction to the craft by one of the century's most distinguished practitioners.Though the book is written from a chemical engineering viewpoint, the principles and pitfalls are common to all mathematical modeling of physical systems. Seventeen of the author's frequently cited papers are reprinted to illus

  8. Problem Based Learning for engineering.

    Science.gov (United States)

    Kumar, Dinesh; Radcliffe, Pj

    2017-07-01

    the role of Problem Based Learning (PBL) is relative clear in domains such as medicine but its efficacy in engineering is as yet less certain. To clarify the role of PBL in engineering, a 3 day workshop was conducted for senior Brazilian engineering academics where they were given the theory and then an immersive PBL experience. One major purpose for running this workshop was for them to identify suitable courses where PBL could be considered. During this workshop, they were split in teams and given a diverse range of problems. At the conclusion of the workshop, a quantifiable survey was conducted and the results show that PBL can deliver superior educational outcomes providing the student group is drawn from the top 5% of the year 12 students, and that significantly higher resources are made available. Thus, any proposed PBL program in engineering must be able to demonstrate that it can meet these requirements before it can move forward to implementation.

  9. Efficiency of Energy Transduction in a Molecular Chemical Engine

    OpenAIRE

    Sasaki, Kazuo; Kanada, Ryo; Amari, Satoshi

    2006-01-01

    A simple model of the two-state ratchet type is proposed for molecular chemical engines that convert chemical free energy into mechanical work and vice versa. The engine works by catalyzing a chemical reaction and turning a rotor. Analytical expressions are obtained for the dependences of rotation and reaction rates on the concentrations of reactant and product molecules, from which the performance of the engine is analyzed. In particular, the efficiency of energy transduction is discussed in...

  10. 2003 Chemical Engineering Division annual technical report

    International Nuclear Information System (INIS)

    Lewis, D.; Graziano, D.; Miller, J. F.; Vandegrift, G.

    2004-01-01

    The Chemical Engineering Division is one of six divisions within the Engineering Research Directorate at Argonne National Laboratory, one of the U.S. government's oldest and largest research laboratories. The University of Chicago oversees the laboratory on behalf of the U.S. Department of Energy (DOE). Argonne's mission is to conduct basic scientific research, to operate national scientific facilities, to enhance the nation's energy resources, to promote national security, and to develop better ways to manage environmental problems. Argonne has the further responsibility of strengthening the nation's technology base by developing innovative technology and transferring it to industry. The Division is a diverse early-stage engineering organization, specializing in the treatment of spent nuclear fuel, development of advanced electrochemical power sources, and management of both high- and low-level nuclear wastes. Additionally, the Division operates the Analytical Chemistry Laboratory, which provides a broad range of analytical services to Argonne and other organizations. The Division is multidisciplinary. Its people have formal training in chemistry; physics; materials science; and electrical, mechanical, chemical, and nuclear engineering. They are specialists in electrochemistry, ceramics, metallurgy, catalysis, materials characterization, nuclear magnetic resonance, repository science, and the nuclear fuel cycle. Our staff have experience working in and collaborating with university, industry and government research and development laboratories throughout the world. Our wide-ranging expertise finds ready application in solving energy, national security, and environmental problems. Division personnel are frequently called on by governmental and industrial organizations for advice and contributions to problem solving in areas that intersect present and past Division programs and activities. Currently, we are engaged in the development of several technologies of

  11. Microbial chemical factories: recent advances in pathway engineering for synthesis of value added chemicals.

    Science.gov (United States)

    Dhamankar, Himanshu; Prather, Kristala L J

    2011-08-01

    The dwindling nature of petroleum and other fossil reserves has provided impetus towards microbial synthesis of fuels and value added chemicals from biomass-derived sugars as a renewable resource. Microbes have naturally evolved enzymes and pathways that can convert biomass into hundreds of unique chemical structures, a property that can be effectively exploited for their engineering into Microbial Chemical Factories (MCFs). De novo pathway engineering facilitates expansion of the repertoire of microbially synthesized compounds beyond natural products. In this review, we visit some recent successes in such novel pathway engineering and optimization, with particular emphasis on the selection and engineering of pathway enzymes and balancing of their accessory cofactors. Copyright © 2011 Elsevier Ltd. All rights reserved.

  12. Thought-evoking approaches in engineering problems

    CERN Document Server

    2014-01-01

    In creating the value-added product in not distant future, it is necessary and inevitable to establish a holistic and though-evoking approach to the engineering problem, which should be at least associated with the inter-disciplinary knowledge and thought processes across the whole engineering spheres. It is furthermore desirable to integrate it with trans-disciplinary aspects ranging from manufacturing culture, through liberal-arts engineering, and industrial sociology.   The thought-evoking approach can be exemplified and typified by representative engineering problems: unveiling essential features in ‘Tangential Force Ratio and Interface Pressure’, prototype development for ‘Bio-mimetic Needle’ and application of ‘Water-jet Machining to Artificial Hip Joint’, product innovation in ‘Heat Sink for Computer’, application of ‘Graph Theory’ to similarity evaluation of production systems, leverage among reciprocity attributes in ‘Industrial and Engineering Designs for Machine Enclosure’,...

  13. Problems in event based engine control

    DEFF Research Database (Denmark)

    Hendricks, Elbert; Jensen, Michael; Chevalier, Alain Marie Roger

    1994-01-01

    Physically a four cycle spark ignition engine operates on the basis of four engine processes or events: intake, compression, ignition (or expansion) and exhaust. These events each occupy approximately 180° of crank angle. In conventional engine controllers, it is an accepted practice to sample...... the engine variables synchronously with these events (or submultiples of them). Such engine controllers are often called event-based systems. Unfortunately the main system noise (or disturbance) is also synchronous with the engine events: the engine pumping fluctuations. Since many electronic engine...... problems on accurate air/fuel ratio control of a spark ignition (SI) engine....

  14. Engineered Barrier System: Physical and Chemical Environment

    International Nuclear Information System (INIS)

    Dixon, P.

    2004-01-01

    The conceptual and predictive models documented in this Engineered Barrier System: Physical and Chemical Environment Model report describe the evolution of the physical and chemical conditions within the waste emplacement drifts of the repository. The modeling approaches and model output data will be used in the total system performance assessment (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. These models evaluate the range of potential water compositions within the emplacement drifts, resulting from the interaction of introduced materials and minerals in dust with water seeping into the drifts and with aqueous solutions forming by deliquescence of dust (as influenced by atmospheric conditions), and from thermal-hydrological-chemical (THC) processes in the drift. These models also consider the uncertainty and variability in water chemistry inside the drift and the compositions of introduced materials within the drift. This report develops and documents a set of process- and abstraction-level models that constitute the engineered barrier system: physical and chemical environment model. Where possible, these models use information directly from other process model reports as input, which promotes integration among process models used for total system performance assessment. Specific tasks and activities of modeling the physical and chemical environment are included in the technical work plan ''Technical Work Plan for: In-Drift Geochemistry Modeling'' (BSC 2004 [DIRS 166519]). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system analysis model reports

  15. Surface chemical problems in coal flotation

    Science.gov (United States)

    Taylor, S. R.; Miller, K. J.; Deurbrouck, A. W.

    1981-02-01

    As the use of coal increases and more fine material is produced by mining and processing, the need for improved methods of coal beneficiation increases. While flotation techniques can help meet these needs, the technique is beset with many problems. These problems involve surface chemical and interfacial properties of the coal-mineral-water slurry systems used in coal flotation. The problems associated with coal flotation include non-selectivity, inefficient reagent utilization, and excessive variablity of results. These problems can be broadely classified as a lack of predictability. The present knowledge of coal flotation is not sufficient, in terms of surface chemical parameters, to allow prediction of the flotation response of a given coal. In this paper, some of the surface chemical properties of coal and coal minerals that need to be defined will be discussed in terms of the problems noted above and their impact on coal cleaning.

  16. Using Simulation to Increase Yields in Chemical Engineering

    Directory of Open Access Journals (Sweden)

    William C. Conley

    2003-06-01

    Full Text Available Trying to increase the yields or profit or efficiency (less pollution of chemical processes is a central goal of the chemical engineer in theory and practice. Certainly sound training in chemistry, business and pollution control help the engineer to set up optimal chemical processes. However, the ever changing demands of customers and business conditions, plus the multivariate complexity of the chemical business can make optimization challenging. Mathematical tools such as statistics and linear programming have certainly been useful to chemical engineers in their pursuit of optimal efficiency. However, some processes can be modeled linearly and some can not. Therefore, presented here will be an industrial chemical process with potentially five variables affecting the yield. Data from over one hundred runs of the process has been collected, but it is not known initially whether the yield relationship is linear or nonlinear. Therefore, the CTSP multivariate correlation coefficient will be calculated for the data to see if a relationship exists among the variables. Then once it is proven that there is a statistically significant relationship, an appropriate linear or nonlinear equation can be fitted to the data, and it can be optimized for use in the chemical plant.

  17. Problem solving in foundation engineering using foundationPro

    CERN Document Server

    Yamin, Mohammad

    2016-01-01

    This book is at once a supplement to traditional foundation engineering textbooks and an independent problem-solving learning tool. The book is written primarily for university students majoring in civil or construction engineering taking foundation analysis and design courses to encourage them to solve design problems. Its main aim is to stimulate problem solving capability and foster self-directed learning. It also explains the use of the foundationPro software, available at no cost, and includes a set of foundation engineering applications. Taking a unique approach, Dr. Yamin summarizes the general step-by-step procedure to solve various foundation engineering problems, illustrates traditional applications of these steps with longhand solutions, and presents the foundationPro solutions. The special structure of the book allows it to be used in undergraduate and graduate foundation design and analysis courses in civil and construction engineering. The book stands as valuable resource for students, faculty, ...

  18. Engineered Barrier System: Physical and Chemical Environment

    Energy Technology Data Exchange (ETDEWEB)

    P. Dixon

    2004-04-26

    The conceptual and predictive models documented in this Engineered Barrier System: Physical and Chemical Environment Model report describe the evolution of the physical and chemical conditions within the waste emplacement drifts of the repository. The modeling approaches and model output data will be used in the total system performance assessment (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. These models evaluate the range of potential water compositions within the emplacement drifts, resulting from the interaction of introduced materials and minerals in dust with water seeping into the drifts and with aqueous solutions forming by deliquescence of dust (as influenced by atmospheric conditions), and from thermal-hydrological-chemical (THC) processes in the drift. These models also consider the uncertainty and variability in water chemistry inside the drift and the compositions of introduced materials within the drift. This report develops and documents a set of process- and abstraction-level models that constitute the engineered barrier system: physical and chemical environment model. Where possible, these models use information directly from other process model reports as input, which promotes integration among process models used for total system performance assessment. Specific tasks and activities of modeling the physical and chemical environment are included in the technical work plan ''Technical Work Plan for: In-Drift Geochemistry Modeling'' (BSC 2004 [DIRS 166519]). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system analysis model reports.

  19. Selective catalytic oxidation of hydrocarbons as a challenge to the chemical engineer

    Energy Technology Data Exchange (ETDEWEB)

    Emig, G [Erlangen-Nuernberg Univ., Erlangen (Germany, F.R.). Inst. fuer Technische Chemie 1

    1977-11-01

    In the conversion of the most important chemical raw materials, natural oil and natural gas, to intermediate or end products, selective catalytic oxidation plays an increasing role. This method makes it possible in many cases to use more economical, single-step processes instead of the older multi-step processes. Using the typical example of propylene oxidation or ammonoxidation, the problems encountered by chemical engineers in the development of a heterogeneous-catalytic method of oxidation are demonstrated. The importance of systematic catalyst development is stressed. General aspects of the development of novel processes or the improvement of existing catalytic processes are discussed.

  20. Experiences on dynamic simulation software in chemical engineering education

    DEFF Research Database (Denmark)

    Komulainen, Tiina M.; Enemark-rasmussen, Rasmus; Sin, Gürkan

    2012-01-01

    Commercial process simulators are increasing interest in the chemical engineer education. In this paper, the use of commercial dynamic simulation software, D-SPICE® and K-Spice®, for three different chemical engineering courses is described and discussed. The courses cover the following topics...

  1. At Age 100, Chemical Engineering Education Faces Changing World.

    Science.gov (United States)

    Krieger, James

    1988-01-01

    Stresses the need for chemical engineering education to keep abreast of current needs. Explores the need for global economics, marketing strategy, product differentiation, and patent law in the curriculum. Questions the abilities of current chemical engineering graduate students in those areas. (MVL)

  2. Group Design Problems in Engineering Design Graphics.

    Science.gov (United States)

    Kelley, David

    2001-01-01

    Describes group design techniques used within the engineering design graphics sequence at Western Washington University. Engineering and design philosophies such as concurrent engineering place an emphasis on group collaboration for the solving of design problems. (Author/DDR)

  3. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    International Nuclear Information System (INIS)

    Jarek, R.

    2004-01-01

    The purpose of this report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The abstraction model is used in the total system performance assessment for the license application (TSPA LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of these abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2004 [DIRS 171156], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports

  4. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    International Nuclear Information System (INIS)

    G.H. Nieder-Westermann

    2005-01-01

    The purpose of this report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The abstraction model is used in the total system performance assessment for the license application (TSPA LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of these abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2004 [DIRS 171156], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports

  5. 6th world congress of chemical engineering. Proceedings

    International Nuclear Information System (INIS)

    2002-01-01

    The 6th World Congress of Chemical Engineering, held in Melbourne, was structured around 6 Vision Lectures which lead to 800 oral presentations and 600 poster presentations, spanning the entire range of chemical engineering. The main topics of the Congress were: environment, health and safety; energy; industrial applications; process simulation and control; management and education and the future. Items in INIS scope have been separately indexed

  6. Antibiotic Algae by Chemical Surface Engineering.

    Science.gov (United States)

    Kerschgens, Isabel P; Gademann, Karl

    2018-03-02

    Chemical cell-surface engineering is a tool for modifying and altering cellular functions. Herein, we report the introduction of an antibiotic phenotype to the green alga Chlamydomonas reinhardtii by chemically modifying its cell surface. Flow cytometry and confocal microscopy studies demonstrated that a hybrid of the antibiotic vancomycin and a 4-hydroxyproline oligomer binds reversibly to the cell wall without affecting the viability or motility of the cells. The modified cells were used to inhibit bacterial growth of Gram-positive Bacillus subtilis cultures. Delivery of the antibiotic from the microalgae to the bacterial cells was verified by microscopy. Our studies provide compelling evidence that 1) chemical surface engineering constitutes a useful tool for the introduction of new, previously unknown functionality, and 2) living microalgae can serve as new platforms for drug delivery. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Applied Mathematical Problems in Engineering

    Directory of Open Access Journals (Sweden)

    Carlos Llopis-Albert

    2016-10-01

    Full Text Available There is a close relationship between engineering and mathematics, which has led to the development of new techniques in recent years. Likewise the developments in technology and computers have led to new ways of teaching mathematics for engineering students and the use of modern techniques and methods.  This research aims to provide insight on how to deal with mathematical problems for engineering students. This is performed by means of a fuzzy set/Qualitative Comparative Analysis applied to conflict resolution of Public Participation Projects in support to the EU Water Framework Directive.

  8. Chemical engineer in business; Kemikaru enjinia to bijinesu

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchiya, Yasuaki

    1999-05-05

    It is Coca-Cola and General Electric Co. (GE) that the aggregate market value is drastically expanding in U.S.A. throughout over past of 15. Direct common point is not very much found to these 2 companies. During over of 15 years, the leadership was demonstrated as management top of both companies, 2 managers who drastically contributed to the enterprise value improvement are the chemical engineer graduate both. It does be not done either mere in which that both persons with the grounded ability of chemical engineering contributed to the enterprise value improvement of the dramatic was not accidental. It is the essence of the chemical engineering,'By discerning essence of the process, the appropriate countermeasure is passed' there was it for the basis of the management of both persons. (NEDO)

  9. Brewing as a Comprehensive Learning Platform in Chemical Engineering

    Science.gov (United States)

    Nielsen, Rudi P.; Sørensen, Jens L.; Simonsen, Morten E.; Madsen, Henrik T.; Muff, Jens; Strandgaard, Morten; Søgaard, Erik G.

    2016-01-01

    Chemical engineering is mostly taught using traditional classroom teaching and laboratory experiments when possible. Being a wide discipline encompassing topics such as analytical chemistry, process design, and microbiology, it may be argued that brewing of beer has many relations to chemical engineering topic-wise. This work illustrates how…

  10. Providing solutions to engineering problems

    International Nuclear Information System (INIS)

    Connop, R.P.P.

    1991-01-01

    BNFL has acquired unique experience over a period of 40 years in specifying, designing and constructing spent fuel reprocessing and associated waste management plant. This experience is currently used to support a pound 5.5 billion capital investment programme. This paper reviews a number of engineering problems and their solutions to highlight BNFL experience in providing comprehensive specification, design and engineering and project management services. (author)

  11. Engineering yeast metabolism for production of fuels and chemicals

    DEFF Research Database (Denmark)

    Nielsen, Jens

    2016-01-01

    faster development of metabolically engineered strains that can be used for production of fuels and chemicals. The yeast Saccharomyces cerevisiae is widely used for production of fuels, chemicals, pharmaceuticals and materials. Through metabolic engineering of this yeast a number of novel industrial...... as for metabolic design. In this lecture it will be demonstrated how the Design-Build-Test cycle of metabolic engineering has allowed for development of yeast cell factories for production of a range of different fuels and chemicals. Some examples of different technologies will be presented together with examples......Metabolic engineering relies on the Design-Build-Test cycle. This cycle includes technologies like mathematical modeling of metabolism, genome editing and advanced tools for phenotypic characterization. In recent years there have been advances in several of these technologies, which has enabled...

  12. Combustion engineering

    CERN Document Server

    Ragland, Kenneth W

    2011-01-01

    Introduction to Combustion Engineering The Nature of Combustion Combustion Emissions Global Climate Change Sustainability World Energy Production Structure of the Book   Section I: Basic Concepts Fuels Gaseous Fuels Liquid Fuels Solid Fuels Problems Thermodynamics of Combustion Review of First Law Concepts Properties of Mixtures Combustion StoichiometryChemical EnergyChemical EquilibriumAdiabatic Flame TemperatureChemical Kinetics of CombustionElementary ReactionsChain ReactionsGlobal ReactionsNitric Oxide KineticsReactions at a Solid SurfaceProblemsReferences  Section II: Combustion of Gaseous and Vaporized FuelsFlamesLaminar Premixed FlamesLaminar Flame TheoryTurbulent Premixed FlamesExplosion LimitsDiffusion FlamesGas-Fired Furnaces and BoilersEnergy Balance and EfficiencyFuel SubstitutionResidential Gas BurnersIndustrial Gas BurnersUtility Gas BurnersLow Swirl Gas BurnersPremixed-Charge Engine CombustionIntroduction to the Spark Ignition EngineEngine EfficiencyOne-Zone Model of Combustion in a Piston-...

  13. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    R. Jarek

    2004-11-23

    The purpose of this report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The abstraction model is used in the total system performance assessment for the license application (TSPA LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of these abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2004 [DIRS 171156], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports.

  14. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    G.H. Nieder-Westermann

    2005-04-07

    The purpose of this report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The abstraction model is used in the total system performance assessment for the license application (TSPA LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of these abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2004 [DIRS 171156], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports.

  15. Sustainability in Chemical Engineering Curriculum

    Science.gov (United States)

    Glassey, Jarka; Haile, Sue

    2012-01-01

    Purpose: The purpose of this paper is to describe a concentrated strategy to embed sustainability teaching into a (chemical) engineering undergraduate curriculum throughout the whole programme. Innovative teaching approaches in subject-specific context are described and their efficiency investigated. Design/methodology/approach: The activities in…

  16. A Comparative Analysis of Software Engineering with Mature Engineering Disciplines Using a Problem-Solving Perspective

    NARCIS (Netherlands)

    Tekinerdogan, B.; Aksit, Mehmet; Dogru, Ali H.; Bicer, Veli

    2011-01-01

    Software engineering is compared with traditional engineering disciplines using a domain specific problem-solving model called Problem-Solving for Engineering Model (PSEM). The comparative analysis is performed both from a historical and contemporary view. The historical view provides lessons on the

  17. Engineered Barrier System: Physical and Chemical Environment Model

    International Nuclear Information System (INIS)

    Jolley, D. M.; Jarek, R.; Mariner, P.

    2004-01-01

    The conceptual and predictive models documented in this Engineered Barrier System: Physical and Chemical Environment Model report describe the evolution of the physical and chemical conditions within the waste emplacement drifts of the repository. The modeling approaches and model output data will be used in the total system performance assessment (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. These models evaluate the range of potential water compositions within the emplacement drifts, resulting from the interaction of introduced materials and minerals in dust with water seeping into the drifts and with aqueous solutions forming by deliquescence of dust (as influenced by atmospheric conditions), and from thermal-hydrological-chemical (THC) processes in the drift. These models also consider the uncertainty and variability in water chemistry inside the drift and the compositions of introduced materials within the drift. This report develops and documents a set of process- and abstraction-level models that constitute the engineered barrier system: physical and chemical environment model. Where possible, these models use information directly from other process model reports as input, which promotes integration among process models used for total system performance assessment. Specific tasks and activities of modeling the physical and chemical environment are included in the technical work plan ''Technical Work Plan for: In-Drift Geochemistry Modeling'' (BSC 2004 [DIRS 166519]). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system analysis model reports

  18. Matrices in Engineering Problems

    CERN Document Server

    Tobias, Marvin

    2011-01-01

    This book is intended as an undergraduate text introducing matrix methods as they relate to engineering problems. It begins with the fundamentals of mathematics of matrices and determinants. Matrix inversion is discussed, with an introduction of the well known reduction methods. Equation sets are viewed as vector transformations, and the conditions of their solvability are explored. Orthogonal matrices are introduced with examples showing application to many problems requiring three dimensional thinking. The angular velocity matrix is shown to emerge from the differentiation of the 3-D orthogo

  19. Future of Chemical Engineering: Integrating Biology into the Undergraduate ChE Curriculum

    Science.gov (United States)

    Mosto, Patricia; Savelski, Mariano; Farrell, Stephanie H.; Hecht, Gregory B.

    2007-01-01

    Integrating biology in the chemical engineering curriculum seems to be the future for chemical engineering programs nation and worldwide. Rowan University's efforts to address this need include a unique chemical engineering curriculum with an intensive biology component integrated throughout from freshman to senior years. Freshman and Sophomore…

  20. An Integrated Architecture for Engineering Problem Solving

    National Research Council Canada - National Science Library

    Pisan, Yusuf

    1998-01-01

    .... This thesis describes the Integrated Problem Solving Architecture (IPSA) that combines qualitative, quantitative and diagrammatic reasoning skills to produce annotated solutions to engineering problems...

  1. Class and Home Problems: Optimization Problems

    Science.gov (United States)

    Anderson, Brian J.; Hissam, Robin S.; Shaeiwitz, Joseph A.; Turton, Richard

    2011-01-01

    Optimization problems suitable for all levels of chemical engineering students are available. These problems do not require advanced mathematical techniques, since they can be solved using typical software used by students and practitioners. The method used to solve these problems forces students to understand the trends for the different terms…

  2. Advances in chemical engineering in nuclear and process industries

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-06-01

    Symposium on Advances in Chemical Engineering in Nuclear and Process Industries dealt with a wide spectrum of areas encompassing various industries such as nuclear, fertilizer, petrochemical, refinery and cement. The topics covered in the symposium dealt with the advancements in the existing fields of science and technologies as well as in some of the emerging technologies such as membrane technology, bio-chemical and photo-chemical engineering etc. with a special emphasis on nuclear related aspects. Papers relevant to INIS are indexed separately.

  3. Advances in chemical engineering in nuclear and process industries

    International Nuclear Information System (INIS)

    1994-06-01

    Symposium on Advances in Chemical Engineering in Nuclear and Process Industries dealt with a wide spectrum of areas encompassing various industries such as nuclear, fertilizer, petrochemical, refinery and cement. The topics covered in the symposium dealt with the advancements in the existing fields of science and technologies as well as in some of the emerging technologies such as membrane technology, bio-chemical and photo-chemical engineering etc. with a special emphasis on nuclear related aspects. Papers relevant to INIS are indexed separately

  4. Defect-engineered graphene chemical sensors with ultrahigh sensitivity.

    Science.gov (United States)

    Lee, Geonyeop; Yang, Gwangseok; Cho, Ara; Han, Jeong Woo; Kim, Jihyun

    2016-05-25

    We report defect-engineered graphene chemical sensors with ultrahigh sensitivity (e.g., 33% improvement in NO2 sensing and 614% improvement in NH3 sensing). A conventional reactive ion etching system was used to introduce the defects in a controlled manner. The sensitivity of graphene-based chemical sensors increased with increasing defect density until the vacancy-dominant region was reached. In addition, the mechanism of gas sensing was systematically investigated via experiments and density functional theory calculations, which indicated that the vacancy defect is a major contributing factor to the enhanced sensitivity. This study revealed that defect engineering in graphene has significant potential for fabricating ultra-sensitive graphene chemical sensors.

  5. The History of Chemical Engineering and Pedagogy: The Paradox of Tradition and Innovation

    Science.gov (United States)

    Wankat, Phillip C.

    2009-01-01

    The Massachusetts Institute of Technology started the first US chemical engineering program six score years ago. Since that time, the chemical engineering curriculum has evolved. The latest versions of the curriculum are attempts to broaden chemical engineering to add product engineering, biology and nanotechnology to the traditional process…

  6. The Problem of Ensuring Reliability of Gas Turbine Engines

    Science.gov (United States)

    Nozhnitsky, Yu A.

    2018-01-01

    Requirements to advanced engines for civil aviation are discussing. Some significant problems of ensuring reliability of advanced gas turbine engines are mentioned. Special attention is paid to successful utilization of new materials and critical technologies. Also the problem of excluding failure of engine part due to low cycle or high cycle fatigue is discussing.

  7. Comparison of Problem Solving from Engineering Design to Software Design

    DEFF Research Database (Denmark)

    Ahmed-Kristensen, Saeema; Babar, Muhammad Ali

    2012-01-01

    Observational studies of engineering design activities can inform the research community on the problem solving models that are employed by professional engineers. Design is defined as an ill-defined problem which includes both engineering design and software design, hence understanding problem...... solving models from other design domains is of interest to the engineering design community. For this paper an observational study of two software design sessions performed for the workshop on “Studying professional Software Design” is compared to analysis from engineering design. These findings provide...... useful insights of how software designers move from a problem domain to a solution domain and the commonalities between software designers’ and engineering designers’ design activities. The software designers were found to move quickly to a detailed design phase, employ co-.evolution and adopt...

  8. Comparison of Problem Solving from Engineering Design to Software Design

    DEFF Research Database (Denmark)

    Ahmed-Kristensen, Saeema; Babar, Muhammad Ali

    2012-01-01

    solving models from other design domains is of interest to the engineering design community. For this paper an observational study of two software design sessions performed for the workshop on “Studying professional Software Design” is compared to analysis from engineering design. These findings provide......Observational studies of engineering design activities can inform the research community on the problem solving models that are employed by professional engineers. Design is defined as an ill-defined problem which includes both engineering design and software design, hence understanding problem...... useful insights of how software designers move from a problem domain to a solution domain and the commonalities between software designers’ and engineering designers’ design activities. The software designers were found to move quickly to a detailed design phase, employ co-.evolution and adopt...

  9. Challenges and opportunities in synthetic biology for chemical engineers.

    Science.gov (United States)

    Luo, Yunzi; Lee, Jung-Kul; Zhao, Huimin

    2013-11-15

    Synthetic biology provides numerous great opportunities for chemical engineers in the development of new processes for large-scale production of biofuels, value-added chemicals, and protein therapeutics. However, challenges across all scales abound. In particular, the modularization and standardization of the components in a biological system, so-called biological parts, remain the biggest obstacle in synthetic biology. In this perspective, we will discuss the main challenges and opportunities in the rapidly growing synthetic biology field and the important roles that chemical engineers can play in its advancement.

  10. Engineered Barrier System: Physical and Chemical Environment Model

    Energy Technology Data Exchange (ETDEWEB)

    D. M. Jolley; R. Jarek; P. Mariner

    2004-02-09

    The conceptual and predictive models documented in this Engineered Barrier System: Physical and Chemical Environment Model report describe the evolution of the physical and chemical conditions within the waste emplacement drifts of the repository. The modeling approaches and model output data will be used in the total system performance assessment (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. These models evaluate the range of potential water compositions within the emplacement drifts, resulting from the interaction of introduced materials and minerals in dust with water seeping into the drifts and with aqueous solutions forming by deliquescence of dust (as influenced by atmospheric conditions), and from thermal-hydrological-chemical (THC) processes in the drift. These models also consider the uncertainty and variability in water chemistry inside the drift and the compositions of introduced materials within the drift. This report develops and documents a set of process- and abstraction-level models that constitute the engineered barrier system: physical and chemical environment model. Where possible, these models use information directly from other process model reports as input, which promotes integration among process models used for total system performance assessment. Specific tasks and activities of modeling the physical and chemical environment are included in the technical work plan ''Technical Work Plan for: In-Drift Geochemistry Modeling'' (BSC 2004 [DIRS 166519]). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system analysis model reports.

  11. Thermodynamics in finite time: A chemically driven engine

    International Nuclear Information System (INIS)

    Ondrechen, M.J.; Berry, R.S.; Andresen, B.

    1980-01-01

    The methods of finite time thermodynamics are applied to processes whose relaxation parameters are chemical rate coefficients within the working fluid. The direct optimization formalism used previously for heat engines with friction and finite heat transfer rates: termed the tricycle method: is extended to heat engines driven by exothermic reactions. The model is a flow reactor coupled by a heat exchanger to an engine. Conditions are established for the achievement of maximum power from such a system. Emphasis is on how the chemical kinetics control the finite-time thermodynamic extrema; first order, first order reversible, and second order reaction kinetics are analyzed. For the types of reactions considered here, there is always a finite positive flow rate in the reactor that yields maximum engine power. Maximum fuel efficiency is always attained in these systems at the uninteresting limit of zero flow rate

  12. Critical technologies: The role of chemistry and chemical engineering

    International Nuclear Information System (INIS)

    1992-01-01

    The purpose of this report is to identify and illustrate key contributions of chemical and chemical engineering research to the development of technologies that have been deemed critical to the economy, security, and well-being of our nation. The report surveys a wide range of vital technologies that are heavily reliant or even critically dependent on chemical or chemical engineering research. Examples were taken from the fields of materials, manufacturing, energy, transportation, public health, information and communications, and the environment. While loosely following the structure of the critical technologies report of the NCTP, our committee decided on a different approach, that of using examples backed up by extensive illustrations

  13. Statics formulas and problems : engineering mechanics 1

    CERN Document Server

    Gross, Dietmar; Wriggers, Peter; Schröder, Jörg; Müller, Ralf

    2017-01-01

    This book contains the most important formulas and more than 160 completely solved problems from Statics. It provides engineering students material to improve their skills and helps to gain experience in solving engineering problems. Particular emphasis is placed on finding the solution path and formulating the basic equations. Topics include: - Equilibrium - Center of Gravity, Center of Mass, Centroids - Support Reactions - Trusses - Beams, Frames, Arches - Cables - Work and Potential Energy - Static and Kinetic Friction - Moments of Inertia.

  14. Energy and environmental challenges to chemical engineers

    International Nuclear Information System (INIS)

    McHenry, K.W.

    1991-01-01

    The National Research Council's report, Frontiers in Chemical Engineering, was written four years ago. Three high-priority research areas concerned with energy and the environment were identified in the report: in situ processing, liquid fuels for the future, and responsible management of hazardous wastes. As outlined in the recently released National Energy Strategy, in situ processing is viewed by the Department of Energy (DOE) primarily through its use in enhanced oil recovery, and some research is still funded. Industry, driven by the economics of low oil prices, is doing little research on in situ processing but much more on reservoir characterization, a prerequisite to processing. Research on liquid fuels for the future is driven more by environmental concerns now than by energy security concerns. It appears to be wise policy for the future to try to solve the alternative fuel problem as quickly and simply as possible. Otherwise, the nation will find itself with a costly and complex fuel and vehicle system that may have to be changed again in a generation. For the interim, we should look closely at reformulated gasoline followed by compressed natural gas, if necessary. In the long run, vehicle systems based on electricity seem most promising for the middle of the next century. To deliver this technology we need to capitalize on three new high-priority research areas: batteries, fuel cells, and nuclear power. For chemical engineers, future challenges of a different sort will be added to the technical challenges, among them are explaining to a skeptical public the wisdom of proceeding to design the interim system of alternative fuel(s) and to move expeditiously to a final solution

  15. Selective catalytic oxidation of hydrocarbons as a challenge to the chemical engineer

    Energy Technology Data Exchange (ETDEWEB)

    Emig, G [Erlangen-Nuernberg Univ., Erlangen (Germany, F.R.). Lehrstuhl fuer Technische Chemie 1

    1978-08-01

    Selective catalytic oxidation is beginning to play a more and more significant role in the process of converting the most important chemical raw materials, crude oil and natural gas, into intermediate and end products. In many cases, this technique makes it possible to replace old processes consisting of many steps by more economical single-step reactions. The typical example of oxidation or ammoxidation of propylene demonstrates the problems which must be solved by the chemical engineer during the development of a heterogeneous catalytic oxidation process. The particular importance of a systematic development of a catalyst is emphasized. General aspects relating to the design of new catalytic processes, or the improvement of existing ones are also discussed.

  16. Challenges and opportunities in synthetic biology for chemical engineers

    Science.gov (United States)

    Luo, Yunzi; Lee, Jung-Kul; Zhao, Huimin

    2012-01-01

    Synthetic biology provides numerous great opportunities for chemical engineers in the development of new processes for large-scale production of biofuels, value-added chemicals, and protein therapeutics. However, challenges across all scales abound. In particular, the modularization and standardization of the components in a biological system, so-called biological parts, remain the biggest obstacle in synthetic biology. In this perspective, we will discuss the main challenges and opportunities in the rapidly growing synthetic biology field and the important roles that chemical engineers can play in its advancement. PMID:24222925

  17. Cyanobacterial metabolic engineering for biofuel and chemical production.

    Science.gov (United States)

    Oliver, Neal J; Rabinovitch-Deere, Christine A; Carroll, Austin L; Nozzi, Nicole E; Case, Anna E; Atsumi, Shota

    2016-12-01

    Rising levels of atmospheric CO 2 are contributing to the global greenhouse effect. Large scale use of atmospheric CO 2 may be a sustainable and renewable means of chemical and liquid fuel production to mitigate global climate change. Photosynthetic organisms are an ideal platform for efficient, natural CO 2 conversion to a broad range of chemicals. Cyanobacteria are especially attractive for these purposes, due to their genetic malleability and relatively fast growth rate. Recent years have yielded a range of work in the metabolic engineering of cyanobacteria and have led to greater knowledge of the host metabolism. Understanding of endogenous and heterologous carbon regulation mechanisms leads to the expansion of productive capacity and chemical variety. This review discusses the recent progress in metabolic engineering of cyanobacteria for biofuel and bulk chemical production since 2014. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Dynamics formulas and problems : engineering mechanics 3

    CERN Document Server

    Gross, Dietmar; Wriggers, Peter; Schröder, Jörg; Müller, Ralf

    2017-01-01

    This book contains the most important formulas and more than 190 completely solved problems from Kinetics and Hydrodynamics. It provides engineering students material to improve their skills and helps to gain experience in solving engineering problems. Particular emphasis is placed on finding the solution path and formulating the basic equations. Topics include: - Kinematics of a Point - Kinetics of a Point Mass- Dynamics of a System of Point Masses - Kinematics of Rigid Bodies - Kinetics of Rigid Bodies - Impact - Vibrations - Non-Inertial Reference Frames - Hydrodynamics .

  19. Results of the 2010 Survey on Teaching Chemical Reaction Engineering

    Science.gov (United States)

    Silverstein, David L.; Vigeant, Margot A. S.

    2012-01-01

    A survey of faculty teaching the chemical reaction engineering course or sequence during the 2009-2010 academic year at chemical engineering programs in the United States and Canada reveals change in terms of content, timing, and approaches to teaching. The report consists of two parts: first, a statistical and demographic characterization of the…

  20. Assessing the Higher National Diploma Chemical Engineering Programme in Ghana: Students' Perspective

    Science.gov (United States)

    Boateng, Cyril D.; Bensah, Edem Cudjoe; Ahiekpor, Julius C.

    2012-01-01

    Chemical engineers have played key roles in the growth of the chemical and allied industries in Ghana but indigenous industries that have traditionally been the domain of the informal sector need to be migrated to the formal sector through the entrepreneurship and innovation of chemical engineers. The Higher National Diploma Chemical Engineering…

  1. Engineering electrical properties of graphene: chemical approaches

    International Nuclear Information System (INIS)

    Kim, Yong-Jin; Kim, Yuna; Hong, Byung Hee; Novoselov, Konstantin

    2015-01-01

    To ensure the high performance of graphene-based devices, it is necessary to engineer the electrical properties of graphene with enhanced conductivity, controlled work function, opened or closed bandgaps, etc. This can be performed by various non-covalent chemical approaches, including molecular adsorption, substrate-induced doping, polymerization on graphene, deposition of metallic thin films or nanoparticles, etc. In addition, covalent approaches such as the substitution of carbon atoms with boron or nitrogen and the functionalization with hydrogen or fluorine are useful to tune the bandgaps more efficiently, with better uniformity and stability. In this review, representative examples of chemically engineered graphene and its device applications will be reviewed, and remaining challenges will be discussed. (topical review)

  2. Improving the Practical Education of Chemical and Pharmaceutical Engineering Majors in Chinese Universities

    Science.gov (United States)

    Zhao, Feng-qing; Yu, Yi-feng; Ren, Shao-feng; Liu, Shao-jie; Rong, Xin-yu

    2014-01-01

    Practical education in chemical engineering has drawn increasing attention in recent years. This paper discusses two approaches to teaching and learning about experiments among upper-level chemical and pharmaceutical engineering majors in China. On the basis of years of experience in teaching chemical and pharmaceutical engineering, we propose the…

  3. Chemical Engineering Education in a Bologna Three Cycle Degree System

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    For the purpose of harmonization of European higher education, Europe’s education system has been going through major changes under what is commonly known as the ”Bologna Process”. The Bologna declaration in 1999 was the start of the introduction of a three cycle degree system in higher education...... in Europe. To date, many European universities have adopted this degree structure. The Working Party on Education (WPE) of the European Federation of Chemical Engineering (EFCE) carried out research to determine the contents of higher education in chemical engineering (ChE) and related disciplines...... such as applied chemistry and process engineering throughout Europe. The result has been a set of recommendations for the first (BS), second (MS) and third (PhD) cycle chemical engineering education aligned to the Bologna Process. They recommend that students studying towards bachelor and masters qualifications...

  4. Chemical engineering challenges and investment opportunities in sustainable energy.

    Science.gov (United States)

    Heller, Adam

    2008-01-01

    The chemical and energy industries are transforming as they adjust to the new era of high-priced petroleum and severe global warming. As a result of the transformation, engineering challenges and investment opportunities abound. Rapid evolution and fast growth are expected in cathode and anode materials as well as polymeric electrolytes for vehicular batteries and in high-performance polymer-ceramic composites for wind turbines, fuel-efficient aircraft, and lighter and safer cars. Unique process-engineering opportunities exist in sand-oil, coal, and possibly also shale liquefaction to produce transportation fuel; and also in genetic engineering of photosynthesizing plants and other organisms for their processing into high-performance biodegradable polymers and high-value-added environmentally friendly chemicals. Also, research on the feasibility of mitigation of global warming through enhancement of CO(2) uptake by the southern oceans by fertilization with trace amounts of iron is progressing. Because chemical engineers are uniquely well trained in mathematical modeling of mass transport, flow, and mixing, and also in cost analysis, they are likely to join the oceanographers and marine biologists in this important endeavor.

  5. Showcasing Chemical Engineering Principles through the Production of Biodiesel from Spent Coffee Grounds

    Science.gov (United States)

    Bendall, Sophie; Birdsall-Wilson, Max; Jenkins, Rhodri; Chew, Y. M. John; Chuck, Christopher J.

    2015-01-01

    Chemical engineering is rarely encountered before higher-level education in the U.S. or in Europe, leaving prospective students unaware of what an applied chemistry or chemical engineering degree entails. In this lab experiment, we report the implementation of a three-day course to showcase chemical engineering principles for 16-17 year olds…

  6. The applicability of chemical alternatives assessment for engineered nanomaterials

    DEFF Research Database (Denmark)

    Hjorth, Rune; Hansen, Steffen Foss; Jacobs, Molly

    2017-01-01

    The use of alternatives assessment to substitute hazardous chemicals with inherently safer options is gaining momentum worldwide as a legislative and corporate strategy to minimize consumer, occupational, and environmental risks. Engineered nanomaterials represent an interesting case......, such as the use of mechanistic toxicity screens and control banding tools, alternatives assessment can be adapted to evaluate engineered nanomaterials both as potential substitutes for chemicals of concern and to ensure safer nanomaterials are incorporated in the design of new products. This article is protected...... for alternatives assessment approaches as they can be considered both emerging “chemicals” of concern, as well as potentially safer alternatives to hazardous chemicals. However, comparing the hazards of nanomaterials to traditional chemicals or to other nanomaterials is challenging and critical elements...

  7. Problems of engineering education and their decision involving industry

    OpenAIRE

    R. P. Simonyants

    2014-01-01

    In Russia, the problems of engineering education are connected with political and economic upheavals of the late last century. At the same time, some leading engineering universities in Russia, such as the Bauman Moscow State Technical University (BMSTU) were resistant to the damaging effects of the crisis. But the methodology and experience of their effective work are insufficiently known.The problems of international engineering school development are also known. The first UNESCO World Repo...

  8. The role of chemical engineering in medicinal research including Alzheimer's.

    Science.gov (United States)

    Kontogeorgis, Georgios M

    2015-01-01

    Various disciplines of chemical engineering, especially thermodynamics and kinetics, play an important role in medicinal research and this has been particularly recognized during the last 10-15 years (von Stockar and van der Wielen, J Biotechnol 59:25, 1997; Prausnitz, Fluid Phase Equilib 53:439, 1989; Prausnitz, Pure Appl Chem 79:1435, 2007; Dey and Prausnitz, Ind Eng Chem Res 50:3, 2011; Prausnitz, J Chem Thermodynamics 35:21, 2003; Tsivintzelis et al. AIChE J 55:756, 2009). It is expected that during the twenty-first century chemical engineering and especially thermodynamics can contribute as significantly to the life sciences development as it has been done with the oil and gas and chemical sectors in the twentieth century. Moreover, it has during the recent years recognized that thermodynamics can help in understanding diseases like human cataract, sickle-cell anemia, Creuzfeldt-Jacob ("mad cow" disease), and Alzheimer's which are connected to "protein aggregation." Several articles in the Perspectives section of prominent chemical engineering journals have addressed this issue (Hall, AIChE J 54:1956, 2008; Vekilov, AIChE J 54:2508, 2008). This work reviews recent applications of thermodynamics (and other areas of chemical engineering) first in drug development and then in the understanding of the mechanism of Alzheimer's and similar diseases.

  9. Teaching Agile Software Engineering Using Problem-Based Learning

    Science.gov (United States)

    El-Khalili, Nuha H.

    2013-01-01

    Many studies have reported the utilization of Problem-Based Learning (PBL) in teaching Software Engineering courses. However, these studies have different views of the effectiveness of PBL. This paper presents the design of an Advanced Software Engineering course for undergraduate Software Engineering students that uses PBL to teach them Agile…

  10. Teaching chemical product design to engineering students: course contents and challenges

    DEFF Research Database (Denmark)

    Skov, Anne Ladegaard; Kiil, Søren

    Chemical product design is not taught in the same way as traditional engineering courses like unit operations or transport phenomena. This paper gives an overview of the challenges that we, as teachers, have faced when teaching chemical product design to engineering students. Specific course...

  11. Technical problems and future underground engineering experiments

    Energy Technology Data Exchange (ETDEWEB)

    Higgins, G H [Lawrence Radiation Laboratory, University of California, Livermore, CA (United States)

    1969-07-01

    The technical problems to be solved in future underground engineering experiments are of two kinds. One concerns adequate description of the variation of nuclear explosion effects with physical nd chemical properties of the explosion site. The other concerns engineering of the explosive detonation system to provide adequate safety and security, concurrently with minimum total costs per explosion. The semiempirical equations for explosion effects can be trusted only in the range of explosive energy, depth of burst, and rock type for which there is prior experience. Effects calculations based on the principles of continuum mechanics and measurable geophysical properties appear to work in the few test cases, such as Gasbuggy, to which they have been applied. These calculational methods must be tested in a variety of situations. The relevance of dynamic and static measurements on Dragon Trail, Bronco, Rulison, Stoop, Ketch, and Pinedale to proving the methods are discussed in this paper. The traditional methods of assembling and fielding nuclear explosives have evolved from practice at the Nevada Test Site. These provide great flexibility and assure maximum recovery of all data from each test, thus minimizing the time required to achieve desired results. Timing and firing, radiation monitoring, explosives assembly and emplacement, explosive performance, weather monitoring, and dynamic measurements of earth and building motion have all been handled traditionally as independent functions. To achieve lower costs in underground engineering experiments and projects, one prototype system combining all electronic, measurement, and communication functions is being built. Much further work will be required to complete this effort, including, especially, an examination of safety criteria and means for assuring operational and public safety at reduced costs. (author)

  12. Technical problems and future underground engineering experiments

    International Nuclear Information System (INIS)

    Higgins, G.H.

    1969-01-01

    The technical problems to be solved in future underground engineering experiments are of two kinds. One concerns adequate description of the variation of nuclear explosion effects with physical nd chemical properties of the explosion site. The other concerns engineering of the explosive detonation system to provide adequate safety and security, concurrently with minimum total costs per explosion. The semiempirical equations for explosion effects can be trusted only in the range of explosive energy, depth of burst, and rock type for which there is prior experience. Effects calculations based on the principles of continuum mechanics and measurable geophysical properties appear to work in the few test cases, such as Gasbuggy, to which they have been applied. These calculational methods must be tested in a variety of situations. The relevance of dynamic and static measurements on Dragon Trail, Bronco, Rulison, Stoop, Ketch, and Pinedale to proving the methods are discussed in this paper. The traditional methods of assembling and fielding nuclear explosives have evolved from practice at the Nevada Test Site. These provide great flexibility and assure maximum recovery of all data from each test, thus minimizing the time required to achieve desired results. Timing and firing, radiation monitoring, explosives assembly and emplacement, explosive performance, weather monitoring, and dynamic measurements of earth and building motion have all been handled traditionally as independent functions. To achieve lower costs in underground engineering experiments and projects, one prototype system combining all electronic, measurement, and communication functions is being built. Much further work will be required to complete this effort, including, especially, an examination of safety criteria and means for assuring operational and public safety at reduced costs. (author)

  13. Linked-Class Problem-Based Learning in Engineering: Method and Evaluation

    Science.gov (United States)

    Hunt, Emily M.; Lockwood-Cooke, Pamela; Kelley, Judy

    2010-01-01

    Problem-Based Learning (PBL) is a problem-centered teaching method with exciting potential in engineering education for motivating and enhancing student learning. Implementation of PBL in engineering education has the potential to bridge the gap between theory and practice. Two common problems are encountered when attempting to integrate PBL into…

  14. Chemical Kinetic Models for Advanced Engine Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Pitz, William J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mehl, Marco [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Westbrook, Charles K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2014-10-22

    The objectives for this project are as follows: Develop detailed chemical kinetic models for fuel components used in surrogate fuels for compression ignition (CI), homogeneous charge compression ignition (HCCI) and reactivity-controlled compression-ignition (RCCI) engines; and Combine component models into surrogate fuel models to represent real transportation fuels. Use them to model low-temperature combustion strategies in HCCI, RCCI, and CI engines that lead to low emissions and high efficiency.

  15. MULTIDISCIPLINARY PROJECTS FOR SECOND YEAR CHEMICAL AND MECHANICAL ENGINEERING STUDENTS

    Directory of Open Access Journals (Sweden)

    MARWAN M. SHAMEL

    2013-04-01

    Full Text Available In the second semester of the second year of a Mechanical Engineering course, students are supposed to take a Module Outside the Main Discipline (MOMD. This module is chosen to be “Product Design Exercise” a module that is offered to Chemical Engineering students at the same stage. The aim was to expose students from both disciplines to an environment in which they are encouraged to interact with and engage team members with a relatively different background. The students were divided into eight groups all comprised of Chemical and Mechanical Engineering students, and they were offered different open-ended projects that were selected to exploit the knowledge developed by the students thus far and they were slightly skewed towards Chemical Engineering. The students demonstrated a high level of cooperation and motivation throughout the period of the project. Effective communication and closing of knowledge gaps were prevalent. At the end of the project period, students produced a journal paper in lieu of the project report.

  16. Metabolic Engineering of Chemical Defence Pathways in Plant Disease Control

    DEFF Research Database (Denmark)

    Rook, Frederik

    2016-01-01

    on each topic. The chapter reviews the some of the scientific and technical challenges in metabolic engineering and the new possibilities emerging from recent technological developments. It concludes by discussing the outlook for bioengineered chemical defences as part of crop protection strategies, also...... with antimicrobial properties for use in crop protection. It presents an overview of the metabolic engineering efforts made in the area of plant chemical defence. For in-depth information on the characteristics of a specific class of chemical defence compounds, the reader is referred to the specialized reviews...

  17. Appropriate Programs for Foreign Students in U.S. Chemical Engineering Curricula.

    Science.gov (United States)

    Findley, M. E.

    Chemical engineers in developing countries may need abilities in a number of diverse areas including management, planning, chemistry, equipment, processes, politics, and improvisation. Chemical engineering programs for foreign students can be arranged by informed advisers with student input for inclusion of some of these areas in addition to…

  18. EDITORIAL: Inverse Problems in Engineering

    Science.gov (United States)

    West, Robert M.; Lesnic, Daniel

    2007-01-01

    Presented here are 11 noteworthy papers selected from the Fifth International Conference on Inverse Problems in Engineering: Theory and Practice held in Cambridge, UK during 11-15 July 2005. The papers have been peer-reviewed to the usual high standards of this journal and the contributions of reviewers are much appreciated. The conference featured a good balance of the fundamental mathematical concepts of inverse problems with a diverse range of important and interesting applications, which are represented here by the selected papers. Aspects of finite-element modelling and the performance of inverse algorithms are investigated by Autrique et al and Leduc et al. Statistical aspects are considered by Emery et al and Watzenig et al with regard to Bayesian parameter estimation and inversion using particle filters. Electrostatic applications are demonstrated by van Berkel and Lionheart and also Nakatani et al. Contributions to the applications of electrical techniques and specifically electrical tomographies are provided by Wakatsuki and Kagawa, Kim et al and Kortschak et al. Aspects of inversion in optical tomography are investigated by Wright et al and Douiri et al. The authors are representative of the worldwide interest in inverse problems relating to engineering applications and their efforts in producing these excellent papers will be appreciated by many readers of this journal.

  19. Chemistry and the Internal Combustion Engine II: Pollution Problems.

    Science.gov (United States)

    Hunt, C. B.

    1979-01-01

    Discusses pollution problems which arise from the use of internal combustion (IC) engines in the United Kingdom (UK). The IC engine exhaust emissions, controlling IC engine pollution in the UK, and some future developments are also included. (HM)

  20. Assessing the Higher National Diploma Chemical Engineering programme in Ghana: students' perspective

    Science.gov (United States)

    Boateng, Cyril D.; Cudjoe Bensah, Edem; Ahiekpor, Julius C.

    2012-05-01

    Chemical engineers have played key roles in the growth of the chemical and allied industries in Ghana but indigenous industries that have traditionally been the domain of the informal sector need to be migrated to the formal sector through the entrepreneurship and innovation of chemical engineers. The Higher National Diploma Chemical Engineering programme is being migrated from a subject-based to a competency-based curriculum. This paper evaluates the programme from the point of view of students. Data were drawn from a survey conducted in the department and were analysed using SPSS. The survey involved administering questionnaires to students at all levels in the department. Analysis of the responses indicated that the majority of the students had decided to pursue chemical engineering due to the career opportunities available. Their knowledge of the programme learning outcomes was, however, poor. The study revealed that none of the students was interested in developing indigenous industries.

  1. Problem-Based Learning in Engineering Ethics Courses

    Science.gov (United States)

    Kirkman, Robert

    2016-01-01

    I describe the first stages of a process of design research in which I employ problem-based learning in a course in engineering ethics, which fulfills a requirement for students in engineering degree programs. The aim of the course is to foster development of particular cognitive skills contributing to moral imagination, a capacity to notice,…

  2. Systematic engineering of TCA cycle for optimal production of a four-carbon platform chemical 4-hydroxybutyric acid in Escherichia coli.

    Science.gov (United States)

    Choi, Sol; Kim, Hyun Uk; Kim, Tae Yong; Lee, Sang Yup

    2016-11-01

    To address climate change and environmental problems, it is becoming increasingly important to establish biorefineries for the production of chemicals from renewable non-food biomass. Here we report the development of Escherichia coli strains capable of overproducing a four-carbon platform chemical 4-hybroxybutyric acid (4-HB). Because 4-HB production is significantly affected by aeration level, genome-scale metabolic model-based engineering strategies were designed under aerobic and microaerobic conditions with emphasis on oxidative/reductive TCA branches and glyoxylate shunt. Several different metabolic engineering strategies were employed to develop strains suitable for fermentation both under aerobic and microaerobic conditions. It was found that microaerobic condition was more efficient than aerobic condition in achieving higher titer and productivity of 4-HB. The final engineered strain produced 103.4g/L of 4-HB by microaerobic fed-batch fermentation using glycerol. The aeration-dependent optimization strategy of TCA cycle will be useful for developing microbial strains producing other reduced derivative chemicals of TCA cycle intermediates. Copyright © 2016 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  3. "Human Nature": Chemical Engineering Students' Ideas about Human Relationships with the Natural World

    Science.gov (United States)

    Goldman, Daphne; Assaraf, Orit Ben-Zvi; Shemesh, Julia

    2014-01-01

    While importance of environmental ethics, as a component of sustainable development, in preparing engineers is widely acknowledged, little research has addressed chemical engineers' environmental concerns. This study aimed to address this void by exploring chemical engineering students' values regarding human-nature relationships. The study was…

  4. Curriculum Assessment as a Direct Tool in ABET Outcomes Assessment in a Chemical Engineering Programme

    Science.gov (United States)

    Abu-Jdayil, Basim; Al-Attar, Hazim

    2010-01-01

    The chemical engineering programme at the United Arab Emirates University is designed to fulfil the Accreditation Board for Engineering and Technology (ABET) (A-K) EC2000 criteria. The Department of Chemical & Petroleum Engineering has established a well-defined process for outcomes assessment for the chemical engineering programme in order to…

  5. Teaching problem-solving skills to nuclear engineering students

    Science.gov (United States)

    Waller, E.; Kaye, M. H.

    2012-08-01

    Problem solving is an essential skill for nuclear engineering graduates entering the workforce. Training in qualitative and quantitative aspects of problem solving allows students to conceptualise and execute solutions to complex problems. Solutions to problems in high consequence fields of study such as nuclear engineering require rapid and accurate analysis of the problems, design of solutions (focusing on public safety, environmental stewardship and ethics), solution execution and monitoring results. A three-month course in problem solving, modelling and simulation was designed and a collaborative approach was undertaken with instructors from both industry and academia. Training was optimised for the laptop-based pedagogy, which provided unique advantages for a course that includes modelling and simulation components. The concepts and tools learned as part of the training were observed to be utilised throughout the duration of student university studies and interviews with students who have entered the workforce indicate that the approaches learned and practised are retained long term.

  6. Chemical engineering and thermodynamics using Mat lab

    International Nuclear Information System (INIS)

    Kim Heon; Kim, Moon Gap; Lee, Hak Yeong; Yeo, Yeong Gu; Ham, Seong Won

    2002-02-01

    This book consists of twelve chapters and four appendixes about chemical engineering and thermodynamics using Mat lab, which deals with introduction, energy budget, entropy, thermodynamics process, generalization on any fluid, engineering equation of state for PVT properties, deviation of the function, phase equilibrium of pure fluid, basic of multicomponent, phase equilibrium of compound by state equation, activity model and reaction system. The appendixes is about summary of computer program, related mathematical formula and material property of pure component.

  7. Energy efficiency as an example of cross-discipline collaboration in chemical engineering

    DEFF Research Database (Denmark)

    de Hemptinne, J.-C; Ferrasse, J.-H.; Górak, A.

    2017-01-01

    This paper summarizes the round-table discussion that was held during the European Congress of Chemical Engineering (ECCE) in Nice, France, in October 2015 on this topic. The panellists come from different fields of chemical engineering and have thus brought in different perspectives. The objective...... (industrials, mostly market-driven, or academic), or in terms of discipline. The role of professional societies as the European Federation for Chemical Engineers (EFCE) is stressed as a promotor of collaboration between disciplines.Finally, once willingness for collaboration is identified, the final question...

  8. Guest Editorial: The Professional Status of European Chemists and Chemical Engineers.

    Science.gov (United States)

    Salzer, Reiner; Taylor, Philip; Majcen, Nineta H; De Angelis, Francesco; Wilmet, Sophie; Varella, Evangelia; Kozaris, Ioannis

    2015-07-06

    Which country pays its chemists and chemical engineers the highest salaries? Where can I find a new job quickest? Which chemical sub-discipline offers most jobs? Reliable answers for these and other questions have been derived from the first European employment survey for chemists and chemical engineers, which was carried out in 2013. Here we publish the first general evaluation of the results of this survey. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. My contribution to broadening the base of chemical engineering.

    Science.gov (United States)

    Sargent, Roger W H

    2011-01-01

    This paper is a short account, from a personal viewpoint, of the various contributions I have made to expand the academic basis of chemical engineering from its origin in the unifying concept of unit operations, focussed on process design, to encompassing all the professional activities of industrial chemical engineers. This includes all aspects of planning and scheduling the operations as well as designing and controlling the process plant. The span of my career also happens to include the birth of the age of computing, with all the consequential implications.

  10. Summaries of the 40. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry

    International Nuclear Information System (INIS)

    1997-01-01

    Annual 40. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry has been held in Gdansk on 22-26 September 1997. The most valuable scientific results obtained in Polish Laboratories have been presented in 22 main sections and 7 symposia directed especially at following subjects: analytical chemistry, biochemistry, solid state chemistry and material science, physical chemistry, heteroorganic and coordination chemistry, medical and pharmaceutical chemistry, metalorganic chemistry, inorganic and organic chemistry, polymers chemistry, chemistry and environment protection, theoretical chemistry, chemical didactics, photochemistry, radiation chemistry and chemical kinetics, chemical engineering, catalysis, crystallochemistry, chemical technology, electrochemistry, and instrumental methods

  11. The Chemical Weapons Convention and the Role of Engineers and Scientists

    Directory of Open Access Journals (Sweden)

    Matoušek, J

    2010-02-01

    Full Text Available Chemical weapons, like all military technology, are associated with activities of scientists and engineers. However, chemical weapons differ from any other military technology because they were invented, and their first mass use directly developed by famous chemists. The active contribution of engineers and scientists and their organisations in the negotiations on chemical disarmament, including drafting the Chemical Weapons Convention, is described. Their present and future role in implementing the Convention is analysed, taking into consideration the threats and benefits of advances in science and technology, and stressing the independent expertise of the OPCW Scientific Advisory Board.

  12. Abstracts Book of 42. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry

    International Nuclear Information System (INIS)

    1999-01-01

    Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry is the most important chemical forum of Polish chemists organised annually. The state of art of many fundamental and applied investigations have been presented and discussed. The following scientific sessions and microsymposia have been proposed: plenary session, analytical chemistry, inorganic chemistry, organic chemistry, chemistry and environment, chemistry and technology of polymers, chemistry didactics, electrochemistry, young scientists forum, chemical technology, chemical engineering, high energetics materials, computers in research and teaching of chemistry, structure modelling and polymer properties, silicon-organic compounds

  13. Chemical engineering and chemistry : education in a changing world

    NARCIS (Netherlands)

    Reijenga, J.C.

    2006-01-01

    Current trends in science and engineering research are analyzed, together with an inventory of changes in the field of employment and practice in industry. The resulting demands on university education of chemists and chemical engineers have been translated into a more or less continuous updating of

  14. Solution Tree Problem Solving Procedure for Engineering Analysis ...

    African Journals Online (AJOL)

    Illustrations are provided in the thermofluid engineering area to showcase the procedure's applications. This approach has proved to be a veritable tool for enhancing the problem-solving and computer algorithmic skills of engineering students, eliciting their curiosity, active participation and appreciation of the taught course.

  15. Incorporating Six Sigma Methodology Training into Chemical Engineering Education

    Science.gov (United States)

    Dai, Lenore L.

    2007-01-01

    Six Sigma is a buzz term in today's technology and business world and there has been increasing interest to initiate Six Sigma training in college education. We have successfully incorporated Six Sigma methodology training into a traditional chemical engineering course, Engineering Experimentation, at Texas Tech University. The students have…

  16. The history of Korean Institute Chemical Engineers for fifteen years

    International Nuclear Information System (INIS)

    2012-12-01

    This book reports the history of Korean Institute of Chemical Engineers with commemorative message, three congratulatory address and photos for fifty years. Nest, it consists of five chapters, which deals with development this institute by chronological classification. It reports the development history by activity such as education, research, publishing branch, international activity, data, woman, and executive office. It records challenge of chemical engineering, remembrance for past presidents and appendixes on history and a list of members.

  17. The history of Korean Institute Chemical Engineers for fifteen years

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-12-15

    This book reports the history of Korean Institute of Chemical Engineers with commemorative message, three congratulatory address and photos for fifty years. Nest, it consists of five chapters, which deals with development this institute by chronological classification. It reports the development history by activity such as education, research, publishing branch, international activity, data, woman, and executive office. It records challenge of chemical engineering, remembrance for past presidents and appendixes on history and a list of members.

  18. HEPATIC TISSUE ENGINEERING (MODERN STATE OF THIS PROBLEM

    Directory of Open Access Journals (Sweden)

    Y.S. Gulay

    2014-01-01

    Full Text Available In this article it was discussed the problem of creation implanted hepatic tissue engineering designs as a modern stage of complex investigation for working out bioartifi cial liver support systems. It was determined that for the positive decision of numerous biological and technological problems it is necessary: to use matrices with determined properties, which mimic properties of hepatic extracellular matrix; to use technology for stereotype sowing of these matrices by both parenchymal and non-parenchymal hepatic cells and to improve the technologies for making and assembling of hepatic tissue-engineering designs.

  19. Method of operating a thermal engine powered by a chemical reaction

    Science.gov (United States)

    Ross, J.; Escher, C.

    1988-06-07

    The invention involves a novel method of increasing the efficiency of a thermal engine. Heat is generated by a non-linear chemical reaction of reactants, said heat being transferred to a thermal engine such as Rankine cycle power plant. The novel method includes externally perturbing one or more of the thermodynamic variables of said non-linear chemical reaction. 7 figs.

  20. Problem Based Learning in Engineering Education

    DEFF Research Database (Denmark)

    Dahms, Mona-Lisa; Sauerbier, Gabriele; Stubbe, Korinna

    2006-01-01

    This paper describes a recent EU-project from five European Institutions. The aim was the development and implementation of a new international Master’s programme for staff development, directed towards the introduction of Problem Based Learning methods in the field of engineering education...

  1. Examining the Critical Thinking Dispositions and the Problem Solving Skills of Computer Engineering Students

    Science.gov (United States)

    Özyurt, Özcan

    2015-01-01

    Problem solving is an indispensable part of engineering. Improving critical thinking dispositions for solving engineering problems is one of the objectives of engineering education. In this sense, knowing critical thinking and problem solving skills of engineering students is of importance for engineering education. This study aims to determine…

  2. Design and Control of Chemical Grouting : Volume 3 - Engineering Practice

    Science.gov (United States)

    1983-04-01

    Recent improvements in the engineering practice of chemical grouting have provided increased confidence in this method of ground modification. Designers can significantly improve the success of chemical grouting by defining their grouting program obj...

  3. Problems in steel industry for power engineering

    International Nuclear Information System (INIS)

    Dolbenko, E.T.; Kryanin, I.R.

    1979-01-01

    The main problems of steel industry in power engineering are considered. The effect of charge materials upon steel quality is analyzed. Radical dicision of the problem is the ensurance of power engineering plants with high quality original charge materials, which are quite pure according to impurities such as: iron melted from metallized charge or prereduced pellets. The usage of such materials considerably improves the complex of technological and service properties and structure of large responsible products: vessels of the reactor core, especially large shafts and others. For the most responsible power engineering dies it is necessary to smelt steel of 150-200 tons and above. The main direction of steel melting industry is quality steel melting in large 150-200 tons arc furnaces which are equipped with magnetic stirrer installations. It is marked that the branch of power engineering is equipped with unique installations of out-of-furnace steel refining. It is shown that further increase in the metal quality is possible when vacuum and electroslag technique of melting is used. It permits to reduce considerably the amount of sulphur, gases, nonmetallic inclusions, to increase the metal density, to remove zonal segregation in large steel ingots. The main problem in the field of usage of material, produced by new melting methods is the expansion of the product nomenclature and the development of technical conditions, reflecting the increase in material properties as a result of new technique application. Importance of development and introduction of new automation and testing methods in metallurgical processes is marked

  4. New Laboratory Course for Senior-Level Chemical Engineering Students

    Science.gov (United States)

    Aronson, Mark T.; Deitcher, Robert W.; Xi, Yuanzhou; Davis, Robert J.

    2009-01-01

    A new laboratory course has been developed at the University of Virginia for senior- level chemical engineering students. The new course is based on three 4-week long experiments in bioprocess engineering, energy conversion and catalysis, and polymer synthesis and characterization. The emphasis is on the integration of process steps and the…

  5. Integrating chemical engineering fundamentals in the capstone process design project

    DEFF Research Database (Denmark)

    von Solms, Nicolas; Woodley, John; Johnsson, Jan Erik

    2010-01-01

    Reaction Engineering. In order to incorporate reactor design into process design in a meaningful way, the teachers of the respective courses need to collaborate (Standard 9 – Enhancement of Faculty CDIO skills). The students also see that different components of the chemical engineering curriculum relate......All B.Eng. courses offered at the Technical University of Denmark (DTU) must now follow CDIO standards. The final “capstone” course in the B.Eng. education is Process Design, which for many years has been typical of chemical engineering curricula worldwide. The course at DTU typically has about 30...... of the CDIO standards – especially standard 3 – Integrated Curriculum - means that the course projects must draw on competences provided in other subjects which the students are taking in parallel with Process Design – specifically Process Control and Reaction Engineering. In each semester of the B...

  6. Big Data Analytics in Chemical Engineering.

    Science.gov (United States)

    Chiang, Leo; Lu, Bo; Castillo, Ivan

    2017-06-07

    Big data analytics is the journey to turn data into insights for more informed business and operational decisions. As the chemical engineering community is collecting more data (volume) from different sources (variety), this journey becomes more challenging in terms of using the right data and the right tools (analytics) to make the right decisions in real time (velocity). This article highlights recent big data advancements in five industries, including chemicals, energy, semiconductors, pharmaceuticals, and food, and then discusses technical, platform, and culture challenges. To reach the next milestone in multiplying successes to the enterprise level, government, academia, and industry need to collaboratively focus on workforce development and innovation.

  7. Mechanics of materials formulas and problems : engineering mechanics 2

    CERN Document Server

    Gross, Dietmar; Wriggers, Peter; Schröder, Jörg; Müller, Ralf

    2017-01-01

    This book contains the most important formulas and more than 140 completely solved problems from Mechanics of Materials and Hydrostatics. It provides engineering students material to improve their skills and helps to gain experience in solving engineering problems. Particular emphasis is placed on finding the solution path and formulating the basic equations. Topics include: - Stress - Strain - Hooke’s Law - Tension and Compression in Bars - Bending of Beams - Torsion - Energy Methods - Buckling of Bars - Hydrostatics .

  8. Molecular and multiscale modeling: review on the theories and applications in chemical engineering

    International Nuclear Information System (INIS)

    Morales M, Giovanni; Martinez R, Ramiro

    2010-01-01

    We call molecular modeling to the application of suitable laws in the analysis of phenomena occurred at scales less than those accounted for by the macroscopic world. Such different scales (including micro-, meso- and macro scales), can be linked and integrated in order to improve understanding and predictions of complex physical chemistry phenomena, thus originating a global or multi scale analysis. A considerable amount of chemical engineering phenomena are complex due to the interrelation among these different realms of length and time. Multi scale modeling rises as an alternative for an outstanding mathematical and conceptual representation of such phenomena. This adequate representation may help to design and optimize chemical and petrochemical processes from a microscopic point of view. Herein we present a brief introduction to both molecular and multi scale modeling methods. We also comment and examine opportunities for applying the different levels of modeling to the analysis of industrial problems. The fundamental mathematical machinery of the molecular modelling theories is presented in order to motivate the study of these new engineering tools. Finally, we show a classification of different strategies for applying multilevel analysis, illustrating various examples of each methodology.

  9. Introduction of Life Cycle Assessment and Sustainability Concepts in Chemical Engineering Curricula

    Science.gov (United States)

    Gallego-Schmid, Alejandro; Schmidt Rivera, Ximena C.; Stamford, Laurence

    2018-01-01

    Purpose: The implementation of life cycle assessment (LCA) and carbon footprinting represents an important professional and research opportunity for chemical engineers, but this is not broadly reflected in chemical engineering curricula worldwide. This paper aims to present the implementation of a coursework that is easy to apply, free of cost,…

  10. Abstracts Book of 41. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry

    International Nuclear Information System (INIS)

    1998-01-01

    Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry is the most important scientific forum of Polish Chemists. The state of the art in many basic, fundamental and applied investigations has been presented and discussed. The following scientific sessions and microsymposia have been proposed: theoretical chemistry; molecular interactions; metal compounds - chemical, physical, electronic and biological aspects; catalysis and surface physico-chemistry; polymers - radiochemistry, modifications, physics and analytical methods; organic and bioorganic chemistry; physico-chemistry of condensed matter; chemical metallurgy; environmental protection; inorganic technology; chemistry and technology of coal; radiation chemistry; analytical chemistry; chemical engineering; young scientists forum; chemical didactics; petrochemistry; energetic materials; membranes and membrane processes; medical chemistry

  11. A numerical primer for the chemical engineer

    NARCIS (Netherlands)

    Zondervan, E.

    2015-01-01

    This book provides an introduction to numerical methods for students in chemical engineering. The book starts with a recap on linear algebra. It then presents methods for solving linear and nonlinear equations, with a special focus on Gaussian elimination and Newton’s method. It also discusses

  12. Two-Compartment Pharmacokinetic Models for Chemical Engineers

    Science.gov (United States)

    Kanneganti, Kumud; Simon, Laurent

    2011-01-01

    The transport of potassium permanganate between two continuous-stirred vessels was investigated to help chemical and biomedical engineering students understand two-compartment pharmacokinetic models. Concepts of modeling, mass balance, parameter estimation and Laplace transform were applied to the two-unit process. A good agreement was achieved…

  13. Self-directed questions to improve students' ability in solving chemical problems

    Science.gov (United States)

    Sanjaya, Rahmat Eko; Muna, Khairiatul; Suharto, Bambang; Syahmani

    2017-12-01

    Students' ability in solving chemical problems is seen from their ability to solve chemicals' non-routine problems. It is due to learning faced directly on non-routine problems will generate a meaningful learning for students. Observations in Banjarmasin Public High School 1 (SMA Negeri 1 Banjarmasin) showed that students did not give the expected results when they were given the non-routine problems. Learning activities by emphasizing problem solving was implemented based on the existence of knowledge about cognition and regulation of cognition. Both of these elements are components of metacognition. The self-directed question is a strategy that involves metacognition in solving chemical problems. This research was carried out using classroom action research design in two cycles. Each cycle consists of four stages: planning, action, observation and reflection. The subjects were 34 students of grade XI-4 at majoring science (IPA) of SMA Negeri 1 Banjarmasin. The data were collected using tests of the students' ability in problem solving and non-tests instrument to know the process of implementation of the actions. Data were analyzed with descriptivequantitativeand qualitative analysis. The ability of students in solving chemical problems has increased from an average of 37.96 in cycle I became 61.83 in cycle II. Students' ability to solve chemical problems is viewed based on their ability to answer self-directed questions. Students' ability in comprehension questions increased from 73.04 in the cycle I became 96.32 in cycle II. Connection and strategic questions increased from 54.17 and 16.50 on cycle I became 63.73 and 55.23 on cycle II respectively. In cycle I, reflection questions were 26.96 and elevated into 36.27 in cycle II. The self-directed questions have the ability to help students to solve chemical problems through metacognition questions. Those questions guide students to find solutions in solving chemical problems.

  14. Drug Transport and Pharmacokinetics for Chemical Engineers

    Science.gov (United States)

    Simon, Laurent; Kanneganti, Kumud; Kim, Kwang Seok

    2010-01-01

    Experiments in continuous-stirred vessels were proposed to introduce methods in pharmacokinetics and drug transport to chemical engineering students. The activities can be incorporated into the curriculum to illustrate fundamentals learned in the classroom. An appreciation for the role of pharmacokinetics in drug discovery will also be gained…

  15. Effort problem of chemical pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Okrajni, J.; Ciesla, M.; Mutwil, K. [Silesian Technical University, Katowice (Poland)

    1998-12-31

    The problem of the technical state assessment of the chemical pipelines working under mechanical and thermal loading has been shown in the paper. The pipelines effort after the long time operating period has been analysed. Material geometrical and loading conditions of the crack initiation and crack growth process in the chosen object has been discussed. Areas of the maximal effort have been determined. The material structure charges after the long time operating period have been described. Mechanisms of the crack initiation and crack growth in the pipeline elements have been analysed and mutual relations between the chemical and mechanical influences have been shown. (orig.) 16 refs.

  16. Engineering surveying theory and examination problems for students

    CERN Document Server

    Schofield, W

    2013-01-01

    Engineering Surveying: Theory and Examination Problems for Students, Volume 1, Third Edition discusses topics concerning engineering surveying techniques and instrumentations. The book is comprised of eight chapters that cover several concerns in engineering survey. Chapter 1 discusses the basic concepts of surveying. Chapter 2 deals with simple and precise leveling, while Chapter 3 covers earthworks. The book also talks about the theodolite and its applications, and then discusses optical distance measurement. Curves, underground and hydrographic surveying, and aspects of dimensional control

  17. Engineering Education: Environmental and Chemical Engineering or Technology Curricula--A European Perspective

    Science.gov (United States)

    Glavic, Peter; Lukman, Rebeka; Lozano, Rodrigo

    2009-01-01

    Over recent years, universities have been incorporating sustainable development (SD) into their systems, including their curricula. This article analyses the incorporation of SD into the curricula of chemical and environmental engineering or technology bachelor degrees at universities in the European Union (EU) and European Free Trade Association…

  18. Metabolic Engineering for Production of Biorenewable Fuels and Chemicals: Contributions of Synthetic Biology

    Directory of Open Access Journals (Sweden)

    Laura R. Jarboe

    2010-01-01

    Full Text Available Production of fuels and chemicals through microbial fermentation of plant material is a desirable alternative to petrochemical-based production. Fermentative production of biorenewable fuels and chemicals requires the engineering of biocatalysts that can quickly and efficiently convert sugars to target products at a cost that is competitive with existing petrochemical-based processes. It is also important that biocatalysts be robust to extreme fermentation conditions, biomass-derived inhibitors, and their target products. Traditional metabolic engineering has made great advances in this area, but synthetic biology has contributed and will continue to contribute to this field, particularly with next-generation biofuels. This work reviews the use of metabolic engineering and synthetic biology in biocatalyst engineering for biorenewable fuels and chemicals production, such as ethanol, butanol, acetate, lactate, succinate, alanine, and xylitol. We also examine the existing challenges in this area and discuss strategies for improving biocatalyst tolerance to chemical inhibitors.

  19. Board on chemical sciences and technology

    International Nuclear Information System (INIS)

    1991-01-01

    The Board on Chemical Sciences and Technology organizes and provides direction for standing and ad-hoc committees charged with addressing specific issues relevant to the continued health of the chemical sciences and technology community. Studies currently under the oversight of the BCST include a major survey of the chemical sciences, a complementary survey of chemical engineering, an examination of the problems of biohazards in the laboratory, and an analysis of the roots and magnitude of the problem of obsolescent facilities for research and teaching in departments in the chemical sciences and engineering. The Board continues to respond to specific agency requests for program assessments and advice. BCST members are designated to serve as liaison with major federal agencies or departments that support research in order to help identify ways for the Board to assist these organizations. The BCST maintains close contact with professional societies and non-governmental organizations that share the Board's concern for the health of chemical sciences and technology. Individual Board members are assigned responsibility for liaison with the American Chemical Society, the American Institute of Chemical Engineers, the American Society of Biological Chemists, the Council for Chemical Research, the NAS Chemistry and Biochemistry Sections, and the National Academy of Engineering. In the past few years, the Board has served as a focus and a forum for a variety of issues that relate specifically to the health of chemistry

  20. `Human nature': Chemical engineering students' ideas about human relationships with the natural world

    Science.gov (United States)

    Goldman, Daphne; Ben-Zvi Assaraf, Orit; Shemesh, Julia

    2014-05-01

    While importance of environmental ethics, as a component of sustainable development, in preparing engineers is widely acknowledged, little research has addressed chemical engineers' environmental concerns. This study aimed to address this void by exploring chemical engineering students' values regarding human-nature relationships. The study was conducted with 247 3rd-4th year chemical engineering students in Israeli Universities. It employed the New Ecological Paradigm (NEP)-questionnaire to which students added written explanations. Quantitative analysis of NEP-scale results shows that the students demonstrated moderately ecocentric orientation. Explanations to the NEP-items reveal diverse, ambivalent ideas regarding the notions embodied in the NEP, strong scientific orientation and reliance on technology for addressing environmental challenges. Endorsing sustainability implies that today's engineers be equipped with an ecological perspective. The capacity of Higher Education to enable engineers to develop dispositions about human-nature interrelationships requires adaptation of curricula towards multidisciplinary, integrative learning addressing social-political-economic-ethical perspectives, and implementing critical-thinking within the socio-scientific issues pedagogical approach.

  1. Interactive Mathematica Simulations in Chemical Engineering Courses

    Science.gov (United States)

    Falconer, John L.; Nicodemus, Garret D.

    2014-01-01

    Interactive Mathematica simulations with graphical displays of system behavior are an excellent addition to chemical engineering courses. The Manipulate command in Mathematica creates on-screen controls that allow users to change system variables and see the graphical output almost instantaneously. They can be used both in and outside class. More…

  2. Building an Evaluation Strategy for an Integrated Curriculum in Chemical Engineering

    Science.gov (United States)

    McCarthy, Joseph J.; Parker, Robert S.; Abatan, Adetola; Besterfield-Sacre, Mary

    2011-01-01

    Increasing knowledge integration has gained wide-spread support as an important goal in engineering education. The Chemical Engineering Pillars curriculum at the University of Pittsburgh, unique for its use of block scheduling, is one of the first four-year, integrated curricula in engineering, and is specifically designed to facilitate knowledge…

  3. Recent advances in microbial production of fuels and chemicals using tools and strategies of systems metabolic engineering

    DEFF Research Database (Denmark)

    Cho, Changhee; Choi, So Young; Luo, Zi Wei

    2015-01-01

    The advent of various systems metabolic engineering tools and strategies has enabled more sophisticated engineering of microorganisms for the production of industrially useful fuels and chemicals. Advances in systems metabolic engineering have been made in overproducing natural chemicals...... and producing novel non-natural chemicals. In this paper, we review the tools and strategies of systems metabolic engineering employed for the development of microorganisms for the production of various industrially useful chemicals belonging to fuels, building block chemicals, and specialty chemicals......, in particular focusing on those reported in the last three years. It was aimed at providing the current landscape of systems metabolic engineering and suggesting directions to address future challenges towards successfully establishing processes for the bio-based production of fuels and chemicals from renewable...

  4. Integrating the protein and metabolic engineering toolkits for next-generation chemical biosynthesis.

    Science.gov (United States)

    Pirie, Christopher M; De Mey, Marjan; Jones Prather, Kristala L; Ajikumar, Parayil Kumaran

    2013-04-19

    Through microbial engineering, biosynthesis has the potential to produce thousands of chemicals used in everyday life. Metabolic engineering and synthetic biology are fields driven by the manipulation of genes, genetic regulatory systems, and enzymatic pathways for developing highly productive microbial strains. Fundamentally, it is the biochemical characteristics of the enzymes themselves that dictate flux through a biosynthetic pathway toward the product of interest. As metabolic engineers target sophisticated secondary metabolites, there has been little recognition of the reduced catalytic activity and increased substrate/product promiscuity of the corresponding enzymes compared to those of central metabolism. Thus, fine-tuning these enzymatic characteristics through protein engineering is paramount for developing high-productivity microbial strains for secondary metabolites. Here, we describe the importance of protein engineering for advancing metabolic engineering of secondary metabolism pathways. This pathway integrated enzyme optimization can enhance the collective toolkit of microbial engineering to shape the future of chemical manufacturing.

  5. Chemistry of fossil fuels and biofuels (cambridge series in chemical engineering)

    CERN Document Server

    Schobert, Harold

    2013-01-01

    Focusing on today's major fuel resources - ethanol, biodiesel, wood, natural gas, petroleum products and coal - this book discusses the formation, composition and properties of the fuels, and the ways in which they are processed for commercial use. The book examines the origin of fuels through natural processes such as photosynthesis and the geological transformation of ancient plant material; the relationships between their composition, molecular structures, and physical properties; and the various processes by which they are converted or refined into the fuel products appearing on today's market. Fundamental chemical aspects such as catalysis and the behaviour of reactive intermediates are presented, and global warming and anthropogenic carbon dioxide emissions are also discussed. The book is suitable for graduate students in energy engineering, chemical engineering, mechanical engineering and chemistry, as well as professional scientists and engineers.

  6. Centrifugal Pump Experiment for Chemical Engineering Undergraduates

    Science.gov (United States)

    Vanderslice, Nicholas; Oberto, Richard; Marrero, Thomas R.

    2012-01-01

    The purpose of this paper is to describe a Centrifugal Pump Experiment that provided an experiential learning experience to chemical engineering undergraduates at the University of Missouri in the spring of 2010 in the Unit Operations Laboratory course. Lab equipment was used by senior students with computer-based data and control technology. In…

  7. Genetic engineering and chemical conjugation of potato virus X.

    Science.gov (United States)

    Lee, Karin L; Uhde-Holzem, Kerstin; Fischer, Rainer; Commandeur, Ulrich; Steinmetz, Nicole F

    2014-01-01

    Here we report the genetic engineering and chemical modification of potato virus X (PVX) for the presentation of various peptides, proteins, and fluorescent dyes, or other chemical modifiers. Three different ways of genetic engineering are described and by these means, peptides are successfully expressed not only when the foot and mouth disease virus (FMDV) 2A sequence or a flexible glycine-serine linker is included, but also when the peptide is fused directly to the PVX coat protein. When larger proteins or unfavorable peptide sequences are presented, a partial fusion via the FMDV 2A sequence is preferable. When these PVX chimeras retain the ability to assemble into viral particles and are thus able to infect plants systemically, they can be utilized to inoculate susceptible plants for isolation of sufficient amounts of virus particles for subsequent chemical modification. Chemical modification is required for the display of nonbiological ligands such as fluorophores, polymers, and small drug compounds. We present three methods of chemical bioconjugation. For direct conjugation of small chemical modifiers to solvent exposed lysines, N-hydroxysuccinimide chemistry can be applied. Bio-orthogonal reactions such as copper-catalyzed azide-alkyne cycloaddition or hydrazone ligation are alternatives to achieve more efficient conjugation (e.g., when working with high molecular weight or insoluble ligands). Furthermore, hydrazone ligation offers an attractive route for the introduction of pH-cleavable cargos (e.g., therapeutic molecules).

  8. An approach in building a chemical compound search engine in oracle database.

    Science.gov (United States)

    Wang, H; Volarath, P; Harrison, R

    2005-01-01

    A searching or identifying of chemical compounds is an important process in drug design and in chemistry research. An efficient search engine involves a close coupling of the search algorithm and database implementation. The database must process chemical structures, which demands the approaches to represent, store, and retrieve structures in a database system. In this paper, a general database framework for working as a chemical compound search engine in Oracle database is described. The framework is devoted to eliminate data type constrains for potential search algorithms, which is a crucial step toward building a domain specific query language on top of SQL. A search engine implementation based on the database framework is also demonstrated. The convenience of the implementation emphasizes the efficiency and simplicity of the framework.

  9. The role of chemical engineering in medicinal research including Alzheimer’s

    DEFF Research Database (Denmark)

    Kontogeorgis, Georgios M.

    2015-01-01

    Various disciplines of chemical engineering, especially thermodynamics and kinetics, play an important role in medicinal research and this has been particularly recognized during the last 10–15 years (von Stockar and van der Wielen, J Biotechnol 59:25, 1997; Prausnitz, Fluid Phase Equilib 53......:439, 1989; Prausnitz, Pure Appl Chem 79:1435, 2007; Dey and Prausnitz, Ind Eng Chem Res 50:3, 2011; Prausnitz, J Chem Thermodynamics 35:21, 2003; Tsivintzelis et al. AIChE J 55:756, 2009). It is expected that during the twenty-first century chemical engineering and especially thermodynamics can contribute......” disease), and Alzheimer’s which are connected to “protein aggregation.” Several articles in the Perspectives section of prominent chemical engineering journals have addressed this issue (Hall, AIChE J 54:1956, 2008; Vekilov, AIChE J 54:2508, 2008). This work reviews recent applications of thermodynamics...

  10. Engineering cell factories for producing building block chemicals for bio-polymer synthesis.

    Science.gov (United States)

    Tsuge, Yota; Kawaguchi, Hideo; Sasaki, Kengo; Kondo, Akihiko

    2016-01-21

    Synthetic polymers are widely used in daily life. Due to increasing environmental concerns related to global warming and the depletion of oil reserves, the development of microbial-based fermentation processes for the production of polymer building block chemicals from renewable resources is desirable to replace current petroleum-based methods. To this end, strains that efficiently produce the target chemicals at high yields and productivity are needed. Recent advances in metabolic engineering have enabled the biosynthesis of polymer compounds at high yield and productivities by governing the carbon flux towards the target chemicals. Using these methods, microbial strains have been engineered to produce monomer chemicals for replacing traditional petroleum-derived aliphatic polymers. These developments also raise the possibility of microbial production of aromatic chemicals for synthesizing high-performance polymers with desirable properties, such as ultraviolet absorbance, high thermal resistance, and mechanical strength. In the present review, we summarize recent progress in metabolic engineering approaches to optimize microbial strains for producing building blocks to synthesize aliphatic and high-performance aromatic polymers.

  11. Chemical Product Design

    DEFF Research Database (Denmark)

    Gani, Rafiqul

    2004-01-01

    This paper highlights for a class of chemical products, the design process, their design with respect to the important issues, the need for appropriate tools and finally, lists some of the challenges and opportunities for the process systems engineering (PSE)/computer-aided process engineering...... (CAPE) community. The chemical products considered belong to the following types: chemical/biochemical/agrochemical products, coatings and solvents, food (nutraceuticals), HIM (household, industrial and institutional), personal care, pharmaceuticals and drugs. The challenges and opportunities...... are highlighted in terms of the needs for multi-level modeling with emphasis on property models that are suitable for computer-aided applications, flexible solution strategies that are able to solve a large range of chemical product design problems and finally, a systems chemical product design framework...

  12. Recent advances in microbial production of fuels and chemicals using tools and strategies of systems metabolic engineering.

    Science.gov (United States)

    Cho, Changhee; Choi, So Young; Luo, Zi Wei; Lee, Sang Yup

    2015-11-15

    The advent of various systems metabolic engineering tools and strategies has enabled more sophisticated engineering of microorganisms for the production of industrially useful fuels and chemicals. Advances in systems metabolic engineering have been made in overproducing natural chemicals and producing novel non-natural chemicals. In this paper, we review the tools and strategies of systems metabolic engineering employed for the development of microorganisms for the production of various industrially useful chemicals belonging to fuels, building block chemicals, and specialty chemicals, in particular focusing on those reported in the last three years. It was aimed at providing the current landscape of systems metabolic engineering and suggesting directions to address future challenges towards successfully establishing processes for the bio-based production of fuels and chemicals from renewable resources. Copyright © 2014 Elsevier Inc. All rights reserved.

  13. Unifying principles of irreversibility minimization for efficiency maximization in steady-flow chemically-reactive engines

    International Nuclear Information System (INIS)

    Ramakrishnan, Sankaran; Edwards, Christopher F.

    2014-01-01

    Systems research has led to the conception and development of various steady-flow, chemically-reactive, engine cycles for stationary power generation and propulsion. However, the question that remains unanswered is: What is the maximum-efficiency steady-flow chemically-reactive engine architecture permitted by physics? On the one hand the search for higher-efficiency cycles continues, often involving newer processes and devices (fuel cells, carbon separation, etc.); on the other hand the design parameters for existing cycles are continually optimized in response to improvements in device engineering. In this paper we establish that any variation in engine architecture—parametric change or process-sequence change—contributes to an efficiency increase via one of only two possible ways to minimize total irreversibility. These two principles help us unify our understanding from a large number of parametric analyses and cycle-optimization studies for any steady-flow chemically-reactive engine, and set a framework to systematically identify maximum-efficiency engine architectures. - Highlights: • A unified thermodynamic model to study chemically-reactive engine architectures is developed. • All parametric analyses of efficiency are unified by two irreversibility-minimization principles. • Variations in internal energy transfers yield a net work increase that is greater than engine irreversibility reduced. • Variations in external energy transfers yield a net work increase that is lesser than engine irreversibility reduced

  14. A Chemical Engineering Perspective on the Origins of Life

    Directory of Open Access Journals (Sweden)

    Martha A. Grover

    2015-05-01

    Full Text Available Atoms and molecules assemble into materials, with the material structure determining the properties and ultimate function. Human-made materials and systems have achieved great complexity, such as the integrated circuit and the modern airplane. However, they still do not rival the adaptivity and robustness of biological systems. Understanding the reaction and assembly of molecules on the early Earth is a scientific grand challenge, and also can elucidate the design principles underlying biological materials and systems. This research requires understanding of chemical reactions, thermodynamics, fluid mechanics, heat and mass transfer, optimization, and control. Thus, the discipline of chemical engineering can play a central role in advancing the field. In this paper, an overview of research in the origins field is given, with particular emphasis on the origin of biopolymers and the role of chemical engineering phenomena. A case study is presented to highlight the importance of the environment and its coupling to the chemistry.

  15. An Alternative Route to Chemical Engineering for Minority and Other Students.

    Science.gov (United States)

    Cussler, E. L.

    The following three alternative ways in which minority group chemistry majors may be trained as chemical engineers are examined in this paper: (l) they are admitted as engineers and take the same courses as engineering students at the graduate level; (2) undergraduate courses are taken as part of the transition from chemistry to chemical…

  16. Cyanobacterial chassis engineering for enhancing production of biofuels and chemicals.

    Science.gov (United States)

    Gao, Xinyan; Sun, Tao; Pei, Guangsheng; Chen, Lei; Zhang, Weiwen

    2016-04-01

    To reduce dependence on fossil fuels and curb greenhouse effect, cyanobacteria have emerged as an important chassis candidate for producing biofuels and chemicals due to their capability to directly utilize sunlight and CO2 as the sole energy and carbon sources, respectively. Recent progresses in developing and applying various synthetic biology tools have led to the successful constructions of novel pathways of several dozen green fuels and chemicals utilizing cyanobacterial chassis. Meanwhile, it is increasingly recognized that in order to enhance productivity of the synthetic cyanobacterial systems, optimizing and engineering more robust and high-efficient cyanobacterial chassis should not be omitted. In recent years, numerous research studies have been conducted to enhance production of green fuels and chemicals through cyanobacterial chassis modifications involving photosynthesis, CO2 uptake and fixation, products exporting, tolerance, and cellular regulation. In this article, we critically reviewed recent progresses and universal strategies in cyanobacterial chassis engineering to make it more robust and effective for bio-chemicals production.

  17. Solving a chemical batch scheduling problem by local search

    NARCIS (Netherlands)

    Brucker, P.; Hurink, Johann L.

    1999-01-01

    A chemical batch scheduling problem is modelled in two different ways as a discrete optimization problem. Both models are used to solve the batch scheduling problem in a two-phase tabu search procedure. The method is tested on real-world data.

  18. Incorporating Sustainability into Engineering and Chemical Education Using E-Learning

    Directory of Open Access Journals (Sweden)

    Edmond Sanganyado

    2018-03-01

    Full Text Available The purpose of this study was to develop e-learning activities that could facilitate the integration of sustainability concepts and practices in engineering and chemical education. Using an online learning management system (LMS, undergraduate students in an applied chemistry program at a public university in Zimbabwe participated in an online discussion on the role of chemical reaction engineering in achieving environmental sustainability goals. In the second activity, the students were instructed to prepare a design report for a cost-effective and innovative wastewater treatment plant for a rural hospital. The design report was evaluated through peer review online. Quantitative and qualitative analyses were performed on the two online activities to evaluate student engagement, quality of responses and the incorporation of sustainability into their learning. In the online discussion, 97 comments were made averaging 120 words per comment. Furthermore, the students averaged 3.88 comments, with the majority of comments exhibiting simple and complex argumentation, a deep reflection and widespread use of terms associated with sustainability such as recycling, pollution, waste and the environment. Furthermore, the evaluation of peer reviews revealed that participants demonstrated they could identify the strengths and shortcomings in the design reports. Therefore, this study demonstrated that e-learning, particularly peer review and online discussion, could help chemistry and engineering students appreciate the need for chemical and engineering activities that encourage sustainable development.

  19. Board on chemical sciences and technology

    International Nuclear Information System (INIS)

    1991-01-01

    The Board on Chemical Sciences and Technology organizes and provides direction for standing and ad hoc committees charged with addressing specific issues relevant to the continued health of the chemical sciences and technology community. Studies currently under the oversight of the BCST include a major survey of chemical engineering, an examination of the problems of biohazards in the laboratory, and an analysis of the roots and magnitude of the problem of obsolescent facilities for research and teaching in departments in the chemical sciences and engineering. The Board continues to respond to specific agency requests for program assessments and advice. BCST members are designated to serve as liaison with major federal agencies or departments that support research in order to help identify ways for the board to assist the these organizations. The BCST also maintains close contact with professional societies and nongovernmental organizations that share the Board's concern for the health of chemical sciences and technology. Individual Board members are assigned responsibility for liaison with the American Chemical Society, the American Institute of Chemical Engineers, the American Society of Biological Chemists, the Council for Chemical Research, the Chemistry and Biochemistry Sections of the National Academy of Sciences (NAS), and the National Academy of Engineering (NAE). In the past few years, the Board has served as a focus and a forum for a variety of issues that relate specifically to the health of chemistry. A sampling of these concerns include: industry-university cooperation; basic research funding in DOD, DOE, NIH, and NSF; basic research in the chemistry of life processes; basic research in biochemical engineering; basic research in the science and technology of new materials; and undergraduate education in chemistry and chemical engineering

  20. Evaluation of creative problem-solving abilities in undergraduate structural engineers through interdisciplinary problem-based learning

    Science.gov (United States)

    McCrum, Daniel Patrick

    2017-11-01

    For a structural engineer, effective communication and interaction with architects cannot be underestimated as a key skill to success throughout their professional career. Structural engineers and architects have to share a common language and understanding of each other in order to achieve the most desirable architectural and structural designs. This interaction and engagement develops during their professional career but needs to be nurtured during their undergraduate studies. The objective of this paper is to present the strategies employed to engage higher order thinking in structural engineering students in order to help them solve complex problem-based learning (PBL) design scenarios presented by architecture students. The strategies employed were applied in the experimental setting of an undergraduate module in structural engineering at Queen's University Belfast in the UK. The strategies employed were active learning to engage with content knowledge, the use of physical conceptual structural models to reinforce key concepts and finally, reinforcing the need for hand sketching of ideas to promote higher order problem-solving. The strategies employed were evaluated through student survey, student feedback and module facilitator (this author) reflection. The strategies were qualitatively perceived by the tutor and quantitatively evaluated by students in a cross-sectional study to help interaction with the architecture students, aid interdisciplinary learning and help students creatively solve problems (through higher order thinking). The students clearly enjoyed this module and in particular interacting with structural engineering tutors and students from another discipline.

  1. Chemical genomic guided engineering of gamma-valerolactone tolerant yeast.

    Science.gov (United States)

    Bottoms, Scott; Dickinson, Quinn; McGee, Mick; Hinchman, Li; Higbee, Alan; Hebert, Alex; Serate, Jose; Xie, Dan; Zhang, Yaoping; Coon, Joshua J; Myers, Chad L; Landick, Robert; Piotrowski, Jeff S

    2018-01-12

    Gamma valerolactone (GVL) treatment of lignocellulosic bomass is a promising technology for degradation of biomass for biofuel production; however, GVL is toxic to fermentative microbes. Using a combination of chemical genomics with the yeast (Saccharomyces cerevisiae) deletion collection to identify sensitive and resistant mutants, and chemical proteomics to monitor protein abundance in the presence of GVL, we sought to understand the mechanism toxicity and resistance to GVL with the goal of engineering a GVL-tolerant, xylose-fermenting yeast. Chemical genomic profiling of GVL predicted that this chemical affects membranes and membrane-bound processes. We show that GVL causes rapid, dose-dependent cell permeability, and is synergistic with ethanol. Chemical genomic profiling of GVL revealed that deletion of the functionally related enzymes Pad1p and Fdc1p, which act together to decarboxylate cinnamic acid and its derivatives to vinyl forms, increases yeast tolerance to GVL. Further, overexpression of Pad1p sensitizes cells to GVL toxicity. To improve GVL tolerance, we deleted PAD1 and FDC1 in a xylose-fermenting yeast strain. The modified strain exhibited increased anaerobic growth, sugar utilization, and ethanol production in synthetic hydrolysate with 1.5% GVL, and under other conditions. Chemical proteomic profiling of the engineered strain revealed that enzymes involved in ergosterol biosynthesis were more abundant in the presence of GVL compared to the background strain. The engineered GVL strain contained greater amounts of ergosterol than the background strain. We found that GVL exerts toxicity to yeast by compromising cellular membranes, and that this toxicity is synergistic with ethanol. Deletion of PAD1 and FDC1 conferred GVL resistance to a xylose-fermenting yeast strain by increasing ergosterol accumulation in aerobically grown cells. The GVL-tolerant strain fermented sugars in the presence of GVL levels that were inhibitory to the unmodified strain

  2. Chemical Reaction Engineering: Current Status and Future Directions.

    Science.gov (United States)

    Dudukovic, M. P.

    1987-01-01

    Describes Chemical Reaction Engineering (CRE) as the discipline that quantifies the interplay of transport phenomena and kinetics in relating reactor performance to operating conditions and input variables. Addresses the current status of CRE in both academic and industrial settings and outlines future trends. (TW)

  3. Happy software developers solve problems better: psychological measurements in empirical software engineering.

    Science.gov (United States)

    Graziotin, Daniel; Wang, Xiaofeng; Abrahamsson, Pekka

    2014-01-01

    For more than thirty years, it has been claimed that a way to improve software developers' productivity and software quality is to focus on people and to provide incentives to make developers satisfied and happy. This claim has rarely been verified in software engineering research, which faces an additional challenge in comparison to more traditional engineering fields: software development is an intellectual activity and is dominated by often-neglected human factors (called human aspects in software engineering research). Among the many skills required for software development, developers must possess high analytical problem-solving skills and creativity for the software construction process. According to psychology research, affective states-emotions and moods-deeply influence the cognitive processing abilities and performance of workers, including creativity and analytical problem solving. Nonetheless, little research has investigated the correlation between the affective states, creativity, and analytical problem-solving performance of programmers. This article echoes the call to employ psychological measurements in software engineering research. We report a study with 42 participants to investigate the relationship between the affective states, creativity, and analytical problem-solving skills of software developers. The results offer support for the claim that happy developers are indeed better problem solvers in terms of their analytical abilities. The following contributions are made by this study: (1) providing a better understanding of the impact of affective states on the creativity and analytical problem-solving capacities of developers, (2) introducing and validating psychological measurements, theories, and concepts of affective states, creativity, and analytical-problem-solving skills in empirical software engineering, and (3) raising the need for studying the human factors of software engineering by employing a multidisciplinary viewpoint.

  4. Chemical composition and photochemical reactivity of exhaust from aircraft turbine engines

    Directory of Open Access Journals (Sweden)

    C. W. Spicer

    1994-08-01

    Full Text Available Assessment of the environmental impact of aircraft emissions is required by planners and policy makers. Seveal areas of concern are: 1. exposure of airport workers and urban residents to toxic chemicals emitted when the engines operate at low power (idle and taxi on the ground; 2. contributions to urban photochemical air pollution of aircraft volatile organic and nitrogen oxides emissions from operations around airports; and 3. emissions of nitrogen oxides and particles during high-altitude operation. The environmental impact of chemicals emitted from jet aircraft turbine engines has not been firmly established due to lack of data regarding emission rates and identities of the compounds emitted. This paper describes an experimental study of two different aircraft turbine engines designed to determine detailed organic emissions, as well as emissions of inorganic gases. Emissions were measured at several engine power settings. Measurements were made of detailed organic composition from C1 through C17, CO, CO2, NO, NOx, and polycyclic aromatic hydrocarbons. Measurements were made using a multi-port sampling pro be positioned directly behind the engine in the exhaust exit plane. The emission measurements have been used to determine the organic distribution by carbon number and the distribution by compound class at each engine power level. The sum of the organic species was compared with an independent measurement of total organic carbon to assess the carbon mass balance. A portion of the exhaust was captured and irradiated in outdoor smog chambers to assess the photochemical reactivity of the emissions with respect to ozone formation. The reactivity of emissions from the two engines was apportioned by chemical compound class.

  5. Problems of engineering education and their decision involving industry

    Directory of Open Access Journals (Sweden)

    R. P. Simonyants

    2014-01-01

    Full Text Available In Russia, the problems of engineering education are connected with political and economic upheavals of the late last century. At the same time, some leading engineering universities in Russia, such as the Bauman Moscow State Technical University (BMSTU were resistant to the damaging effects of the crisis. But the methodology and experience of their effective work are insufficiently known.The problems of international engineering school development are also known. The first UNESCO World Report on Engineering (2010 assesses the state of engineering education as follows: worldwide shortage of engineers is a threat to the development of society.Based on the analysis of the current state of engineering education in the world and tendencies of development an urgency of its modernization with the focus on the enhancement of practical component has been shown.Topical problems associated with innovations and modernization in engineering education in the field of aerospace technology were discussed at the first international forum, which was held in Beijing Beyhanskom University (BUAA on 8 - 9 September 2012. The author attended this forum and presented his impressions of its work. It was noted that the role of Russia in the global process to form and develop engineering education is ignored. This opinion sounded, generally, in all speakers' reports, apart from ours.The President BUAA, a Professor Jinpeng Huai, and a Professor Qiushi Li. talked about the problems of building the engineering education system in China. It was emphasized that in China a study of engineering education techniques was motivated by the fact that quality assurance of engineering education at U.S. universities does not meet requirements.Attention is drawn to Dr. David Wisler's report who is a representative of the U.S. aerospace industry (General Electric Aviation corporation, actively promoting networking technology "initiative CDIO».The assessment of the engineering education

  6. Military Engineers and Chemical Warfare Troops (Inzhenernye Voiska Khimicheskie Voiska),

    Science.gov (United States)

    MILITARY FORCES(FOREIGN), *MILITARY ORGANIZATIONS, MILITARY ENGINEERING , INFANTRY, AMPHIBIOUS OPERATIONS, MINELAYING, ARMORED VEHICLES, NUCLEAR...RADIATION, DOSIMETERS, CHEMICAL WARFARE, PROTECTIVE CLOTHING, DECONTAMINATION, HEALTH PHYSICS.

  7. Chemical Information in Scirus and BASE (Bielefeld Academic Search Engine)

    Science.gov (United States)

    Bendig, Regina B.

    2009-01-01

    The author sought to determine to what extent the two search engines, Scirus and BASE (Bielefeld Academic Search Engines), would be useful to first-year university students as the first point of searching for chemical information. Five topics were searched and the first ten records of each search result were evaluated with regard to the type of…

  8. selectivity engineering in sustainable production of chemicals, fuels ...

    Indian Academy of Sciences (India)

    admin

    Cost. Landfill. –400. Source: Tuck et al., Science, 337 (6095): 695-699 10 August ... libraries for novel enzymes that transform lignocellulosics ... Bio-process engineering for optimal production of ... fine chemicals and petrochemical industries. ..... Mole ratio : Epichlorohydrin to acetone of 1:8 , 100 % atom economy. Sr.No.

  9. HBCUs and Chemical Engineering: Analysis of Baccalaureate Programs

    Science.gov (United States)

    Reeves, Sheena; Thompson, Audie

    2018-01-01

    Historically Black Colleges and Universities (HBCUs) provide significant STEM degrees to African Americans. Initiatives toward increasing diversity in STEM fields have been implemented by government and industry leaders. HBCUs annually award over 20% of all African American baccalaureate chemical engineering degrees. This speaks volume to the…

  10. The Intersection of Gender and Race: Exploring Chemical Engineering Students' Attitudes

    Science.gov (United States)

    Goodwin, Allison; Verdín, Dina; Kirn, Adam; Satterfield, Derrick

    2018-01-01

    We surveyed 342 first-year engineering students at four U.S. institutions interested in a chemical engineering career about their feelings of belonging in engineering, motivation, and STEM identities. We compared these students by both gender and race/ethnicity on these attitudinal factors. We found several significant differences in…

  11. Shape Memory Polymers: A Joint Chemical and Materials Engineering Hands-On Experience

    Science.gov (United States)

    Seif, Mujan; Beck, Matthew

    2018-01-01

    Hands-on experiences are excellent tools for increasing retention of first year engineering students. They also encourage interdisciplinary collaboration, a critical skill for modern engineers. In this paper, we describe and evaluate a joint Chemical and Materials Engineering hands-on lab that explores cross-linking and glass transition in…

  12. Engineering cyanobacteria for fuels and chemicals production.

    Science.gov (United States)

    Zhou, Jie; Li, Yin

    2010-03-01

    The world's energy and global warming crises call for sustainable, renewable, carbon-neutral alternatives to replace fossil fuel resources. Currently, most biofuels are produced from agricultural crops and residues, which lead to concerns about food security and land shortage. Compared to the current biofuel production system, cyanobacteria, as autotrophic prokaryotes, do not require arable land and can grow to high densities by efficiently using solar energy, CO(2), water, and inorganic nutrients. Moreover, powerful genetic techniques of cyanobacteria have been developed. For these reasons, cyanobacteria, which carry out oxygenic photosynthesis, are attractive hosts for production of fuels and chemicals. Recently, several chemicals including ethanol, isobutanol and isoprene have been produced by engineered cyanobacteria directly using solar energy, CO(2), and water. Cyanobacterium is therefore a potential novel cell factory for fuels and chemicals production to address global energy security and climate change issues.

  13. Engineering modular polyketide synthases for production of biofuels and industrial chemicals.

    Science.gov (United States)

    Cai, Wenlong; Zhang, Wenjun

    2018-04-01

    Polyketide synthases (PKSs) are one of the most profound biosynthetic factories for producing polyketides with diverse structures and biological activities. These enzymes have been historically studied and engineered to make un-natural polyketides for drug discovery, and have also recently been explored for synthesizing biofuels and industrial chemicals due to their versatility and customizability. Here, we review recent advances in the mechanistic understanding and engineering of modular PKSs for producing polyketide-derived chemicals, and provide perspectives on this relatively new application of PKSs. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Chemical Reaction Engineering Applications in Non-traditional Technologies. A Textbook Supplement.

    Science.gov (United States)

    Savage, Phillip E.; Blaine, Steven

    1991-01-01

    A set of educational materials that have been developed which deal with chemical engineering applications in emerging technologies is described. The organization and the content of the supplemental textbook materials and how they can be integrated into an undergraduate reaction engineering course are discussed. (KR)

  15. Use of Research-Based Instructional Strategies in Core Chemical Engineering Courses

    Science.gov (United States)

    Prince, Michael; Borrego, Maura; Henderson, Charles; Cutler, Stephanie; Froyd, Jeff

    2013-01-01

    Traditional lecturing remains the most prevalent mode of instruction despite overwhelming research showing the increased effectiveness of many alternate instructional strategies. This study examines chemical engineering instructors' awareness and use of 12 such instructional strategies. The study also examines how chemical engineering…

  16. [Development of domain specific search engines].

    Science.gov (United States)

    Takai, T; Tokunaga, M; Maeda, K; Kaminuma, T

    2000-01-01

    As cyber space exploding in a pace that nobody has ever imagined, it becomes very important to search cyber space efficiently and effectively. One solution to this problem is search engines. Already a lot of commercial search engines have been put on the market. However these search engines respond with such cumbersome results that domain specific experts can not tolerate. Using a dedicate hardware and a commercial software called OpenText, we have tried to develop several domain specific search engines. These engines are for our institute's Web contents, drugs, chemical safety, endocrine disruptors, and emergent response for chemical hazard. These engines have been on our Web site for testing.

  17. Metabolic engineering is key to a sustainable chemical industry.

    Science.gov (United States)

    Murphy, Annabel C

    2011-08-01

    The depletion of fossil fuel stocks will prohibit their use as the main feedstock of future industrial processes. Biocatalysis is being increasingly used to reduce fossil fuel reliance and to improve the sustainability, efficiency and cost of chemical production. Even with their current small market share, biocatalyzed processes already generate approximately US$50 billion and it has been estimated that they could be used to produce up to 20% of fine chemicals by 2020. Until the advent of molecular biological technologies, the compounds that were readily accessible from renewable biomass were restricted to naturally-occurring metabolites. However, metabolic engineering has considerably broadened the range of compounds now accessible, providing access to compounds that cannot be otherwise reliably sourced, as well as replacing established chemical processes. This review presents the case for continued efforts to promote the adoption of biocatalyzed processes, highlighting successful examples of industrial chemical production from biomass and/or via biocatalyzed processes. A selection of emerging technologies that may further extend the potential and sustainability of biocatalysis are also presented. As the field matures, metabolic engineering will be increasingly crucial in maintaining our quality of life into a future where our current resources and feedstocks cannot be relied upon.

  18. Learning by Brewing: Beer Production Experiments in the Chemical Engineering Laboratory

    Science.gov (United States)

    Cerretani, Colin; Kelkile, Esayas; Landry, Alexandra

    2017-01-01

    We discuss the successful creation and implementation of a biotechnology track within the chemical engineering unit operations course. The track focuses on engineering principles relevant to brewing. Following laboratory modules investigating heat transfer processes and yeast fermentation kinetics, student groups design and implement a project to…

  19. New Developments of Computational Fluid Dynamics and Their Applications to Practical Engineering Problems

    Science.gov (United States)

    Chen, Hudong

    2001-06-01

    There have been considerable advances in Lattice Boltzmann (LB) based methods in the last decade. By now, the fundamental concept of using the approach as an alternative tool for computational fluid dynamics (CFD) has been substantially appreciated and validated in mainstream scientific research and in industrial engineering communities. Lattice Boltzmann based methods possess several major advantages: a) less numerical dissipation due to the linear Lagrange type advection operator in the Boltzmann equation; b) local dynamic interactions suitable for highly parallel processing; c) physical handling of boundary conditions for complicated geometries and accurate control of fluxes; d) microscopically consistent modeling of thermodynamics and of interface properties in complex multiphase flows. It provides a great opportunity to apply the method to practical engineering problems encountered in a wide range of industries from automotive, aerospace to chemical, biomedical, petroleum, nuclear, and others. One of the key challenges is to extend the applicability of this alternative approach to regimes of highly turbulent flows commonly encountered in practical engineering situations involving high Reynolds numbers. Over the past ten years, significant efforts have been made on this front at Exa Corporation in developing a lattice Boltzmann based commercial CFD software, PowerFLOW. It has become a useful computational tool for the simulation of turbulent aerodynamics in practical engineering problems involving extremely complex geometries and flow situations, such as in new automotive vehicle designs world wide. In this talk, we present an overall LB based algorithm concept along with certain key extensions in order to accurately handle turbulent flows involving extremely complex geometries. To demonstrate the accuracy of turbulent flow simulations, we provide a set of validation results for some well known academic benchmarks. These include straight channels, backward

  20. Development and application of characteristic database for uranium mining and metallurgy in the library of Beijing Research Institute of Chemical Engineering and Metallurgy

    International Nuclear Information System (INIS)

    Gao Renxi

    2012-01-01

    Beijing Research Institute of Chemical Engineering and Metallurgy (BRICEM) is a multi disciplinary comprehensive research institute engaged in uranium mining, engineering design and related material researches. After 53 years of researches and development, BRICEM has accumulated a plenty of valuable data and resources. By analyzing the actual conditions of BRICEM's technological database, this thesis aims to propose the idea of building a characteristic database for uranium mining and metallurgy. It gives an in-depth analysis on content design, development status and problems of database development, in order to come up with solutions to these problems, as well as suggestions on the future development plans of the characteristic database. (author)

  1. Chemical composition and photochemical reactivity of exhaust from aircraft turbine engines

    Directory of Open Access Journals (Sweden)

    T. F. Lyon

    Full Text Available Assessment of the environmental impact of aircraft emissions is required by planners and policy makers. Seveal areas of concern are: 1. exposure of airport workers and urban residents to toxic chemicals emitted when the engines operate at low power (idle and taxi on the ground; 2. contributions to urban photochemical air pollution of aircraft volatile organic and nitrogen oxides emissions from operations around airports; and 3. emissions of nitrogen oxides and particles during high-altitude operation. The environmental impact of chemicals emitted from jet aircraft turbine engines has not been firmly established due to lack of data regarding emission rates and identities of the compounds emitted. This paper describes an experimental study of two different aircraft turbine engines designed to determine detailed organic emissions, as well as emissions of inorganic gases. Emissions were measured at several engine power settings. Measurements were made of detailed organic composition from C1 through C17, CO, CO2, NO, NOx, and polycyclic aromatic hydrocarbons. Measurements were made using a multi-port sampling pro be positioned directly behind the engine in the exhaust exit plane. The emission measurements have been used to determine the organic distribution by carbon number and the distribution by compound class at each engine power level. The sum of the organic species was compared with an independent measurement of total organic carbon to assess the carbon mass balance. A portion of the exhaust was captured and irradiated in outdoor smog chambers to assess the photochemical reactivity of the emissions with respect to ozone formation. The reactivity of emissions from the two engines was apportioned by chemical compound class.

  2. Requirements Engineering as Creative Problem Solving: A Research Agenda for Idea Finding

    OpenAIRE

    Maiden, N.; Jones, S.; Karlsen, I. K.; Neill, R.; Zachos, K.; Milne, A.

    2010-01-01

    This vision paper frames requirements engineering as a creative problem solving process. Its purpose is to enable requirements researchers and practitioners to recruit relevant theories, models, techniques and tools from creative problem solving to understand and support requirements processes more effectively. It uses 4 drivers to motivate the case for requirements engineering as a creative problem solving process. It then maps established requirements activities onto one of the longest-esta...

  3. Magnetic Resonance Imaging and Velocity Mapping in Chemical Engineering Applications.

    Science.gov (United States)

    Gladden, Lynn F; Sederman, Andrew J

    2017-06-07

    This review aims to illustrate the diversity of measurements that can be made using magnetic resonance techniques, which have the potential to provide insights into chemical engineering systems that cannot readily be achieved using any other method. Perhaps the most notable advantage in using magnetic resonance methods is that both chemistry and transport can be followed in three dimensions, in optically opaque systems, and without the need for tracers to be introduced into the system. Here we focus on hydrodynamics and, in particular, applications to rheology, pipe flow, and fixed-bed and gas-solid fluidized bed reactors. With increasing development of industrially relevant sample environments and undersampling data acquisition strategies that can reduce acquisition times to chemical engineering research.

  4. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    International Nuclear Information System (INIS)

    R. Jarek

    2005-01-01

    The purpose of this model report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The resulting seepage evaporation and gas abstraction models are used in the total system performance assessment for the license application (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2005 [DIRS 173782], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports. To be consistent with other project documents that address features, events, and processes (FEPs), Table 6.14.1 of the current report includes updates to FEP numbers and FEP subjects for two FEPs identified in the technical work plan (TWP) governing this report (BSC 2005 [DIRS 173782]). FEP 2.1.09.06.0A (Reduction-oxidation potential in EBS), as listed in Table 2 of the TWP (BSC 2005 [DIRS 173782]), has been updated in the current report to FEP 2.1.09.06.0B (Reduction-oxidation potential in Drifts; see Table 6.14-1). FEP 2.1.09.07.0A (Reaction kinetics in EBS), as listed in Table 2 of the TWP (BSC 2005 [DIRS 173782]), has been updated in the current report to FEP 2.1.09.07.0B (Reaction kinetics in Drifts; see Table 6.14-1). These deviations from the TWP are justified because they improve integration with FEPs documents. The updates

  5. Numerical simulations of coupled problems in engineering

    CERN Document Server

    2014-01-01

    This book presents and discusses mathematical models, numerical methods and computational techniques used for solving coupled problems in science and engineering. It takes a step forward in the formulation and solution of real-life problems with a multidisciplinary vision, accounting for all of the complex couplings involved in the physical description. Simulation of multifaceted physics problems is a common task in applied research and industry. Often a suitable solver is built by connecting together several single-aspect solvers into a network. In this book, research in various fields was selected for consideration: adaptive methodology for multi-physics solvers, multi-physics phenomena and coupled-field solutions, leading to computationally intensive structural analysis. The strategies which are used to keep these problems computationally affordable are of special interest, and make this an essential book.

  6. Review on study of multi-physics in environment engineering

    International Nuclear Information System (INIS)

    Liu Shanli; Zhao Jian; Sheng Jinchang

    2006-01-01

    This paper analyzes some problems on multi-field coupling ones between seepage mechanics and other physical and chemical processes (such as temperature field. stress field, solute transport. chemical action and so on) in environment engineering, it explains the research theory of multi-field coupling, it summarizes the abroad and domestic research about the model of multi-field problem and finally it looks into the future of research tendency in environment engineering. (authors)

  7. Materials of 44. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry

    International Nuclear Information System (INIS)

    2001-01-01

    Scientific assemblies of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry are the most important chemical meeting organised annually in Poland. Basic as well as application studies in all chemical branches have been extensively presented. The next subjects was proposed as scientific sessions and symposia topics: solid state chemistry; didactics of chemistry; electrochemistry; biologically active compounds; geochemistry; organic chemistry; physical chemistry; environment quality and protection; coordination chemistry; chemical technology; polymers; explosive materials; analytical chemistry; theoretical chemistry

  8. Integrating Industry in Project Organized Problem Based Learning for Engineering Educations

    DEFF Research Database (Denmark)

    Nielsen, Kirsten M.

    2006-01-01

    This abstract deals with the challenge of establishing engineering student projects in collaboration with industry. Based on empirical results a set of advices for industrial collaboration in project oriented problem based learning are formulated......This abstract deals with the challenge of establishing engineering student projects in collaboration with industry. Based on empirical results a set of advices for industrial collaboration in project oriented problem based learning are formulated...

  9. Promoting Collaborative Problem-Solving Skills in a Course on Engineering Grand Challenges

    Science.gov (United States)

    Zou, Tracy X. P.; Mickleborough, Neil C.

    2015-01-01

    The ability to solve problems with people of diverse backgrounds is essential for engineering graduates. A course on engineering grand challenges was designed to promote collaborative problem-solving (CPS) skills. One unique component is that students need to work both within their own team and collaborate with the other team to tackle engineering…

  10. Global Controllability of Chemical Reactions

    OpenAIRE

    Drexler, Dániel András; Tóth, János

    2015-01-01

    Controllability of chemical reactions is an important problem in chemical engineering science. In control theory, analysis of the controllability of linear systems is well-founded, however the dynamics of chemical reactions is usually nonlinear. Global controllability properties of chemical reactions are analyzed here based on the Lie-algebra of the vector fields associated to elementary reactions. A chemical reaction is controllable almost everywhere if all the reaction rate coefficients can...

  11. Electrical circuits in biomedical engineering problems with solutions

    CERN Document Server

    Keskin, Ali Ümit

    2017-01-01

    This authored monograph presents a comprehensive and in-depth analysis of electrical circuit theory in biomedical engineering, ideally suited as textbook for a course program. The book contains methods and theory, but the topical focus is placed on practical applications of circuit theory, including problems, solutions and case studies. The target audience primarily comprises researchers and experts in electrical engineering who intend to embark on biomedical applications. The book is also very well suited for graduate students in the field. .

  12. Modeling of coupled differential equations for cellular chemical signaling pathways: Implications for assay protocols utilized in cellular engineering.

    Science.gov (United States)

    O'Clock, George D

    2016-08-01

    Cellular engineering involves modification and control of cell properties, and requires an understanding of fundamentals and mechanisms of action for cellular derived product development. One of the keys to success in cellular engineering involves the quality and validity of results obtained from cell chemical signaling pathway assays. The accuracy of the assay data cannot be verified or assured if the effect of positive feedback, nonlinearities, and interrelationships between cell chemical signaling pathway elements are not understood, modeled, and simulated. Nonlinearities and positive feedback in the cell chemical signaling pathway can produce significant aberrations in assay data collection. Simulating the pathway can reveal potential instability problems that will affect assay results. A simulation, using an electrical analog for the coupled differential equations representing each segment of the pathway, provides an excellent tool for assay validation purposes. With this approach, voltages represent pathway enzyme concentrations and operational amplifier feedback resistance and input resistance values determine pathway gain and rate constants. The understanding provided by pathway modeling and simulation is strategically important in order to establish experimental controls for assay protocol structure, time frames specified between assays, and assay concentration variation limits; to ensure accuracy and reproducibility of results.

  13. Students’ conceptions and problem-solving ability on topic chemical thermodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Diawati, Chansyanah, E-mail: chansyanahd@yahoo.com [Program Studi Pendidikan Kimia Jurusan PMIPA FKIP, Universitas Lampung, Jl. Prof. Dr. Soemantri Brodjonegoro No. 1 Gedung Meneng, Bandar Lampung35145 (Indonesia)

    2016-02-08

    The enthalpy concept and its change were introduced to describe the forms of internal energy transfer in chemical reactions. Likewise, the concepts of exothermic and endothermic reactions introduced as a consequence of heat transfer form. In the heat measurement process at constant pressure, work is often ignored. The exothermic or endothermic reactions, usually only based on the increase or decrease of the reaction temperature, without associated with the internal energy. Depictions of enthalpy and its change assumed closely related to students’ problem-solving ability. Therefore, the study to describe pre-service chemistry teacher student’s conceptions and problem-solving ability on topic chemical thermodynamics has been done. This research was a case study of chemical education course in Provinsi Lampung. The subjects of this study were 42 students who attend the chemical thermodynamics course. Questions about exothermic and endothermic reactions, enthalpy and its change, as well as internal energy and its change were given in the form of an essay exam questions. Answers related to conception qualitatively categorized, while problem solving answers were scored and assessed. The results showed that, in general, students were having problems in enthalpy and describe the changes in the form of heat and work. The highest value of problem solving ability obtained 26.67 from the maximum value of 100. The lowest value was 0, and the average value was 14.73. These results show that the problem-solving ability of pre-service chemistry teacher students was low. The results provide insight to researchers, and educators to develop learning or lab work on this concept.

  14. Students’ conceptions and problem-solving ability on topic chemical thermodynamics

    International Nuclear Information System (INIS)

    Diawati, Chansyanah

    2016-01-01

    The enthalpy concept and its change were introduced to describe the forms of internal energy transfer in chemical reactions. Likewise, the concepts of exothermic and endothermic reactions introduced as a consequence of heat transfer form. In the heat measurement process at constant pressure, work is often ignored. The exothermic or endothermic reactions, usually only based on the increase or decrease of the reaction temperature, without associated with the internal energy. Depictions of enthalpy and its change assumed closely related to students’ problem-solving ability. Therefore, the study to describe pre-service chemistry teacher student’s conceptions and problem-solving ability on topic chemical thermodynamics has been done. This research was a case study of chemical education course in Provinsi Lampung. The subjects of this study were 42 students who attend the chemical thermodynamics course. Questions about exothermic and endothermic reactions, enthalpy and its change, as well as internal energy and its change were given in the form of an essay exam questions. Answers related to conception qualitatively categorized, while problem solving answers were scored and assessed. The results showed that, in general, students were having problems in enthalpy and describe the changes in the form of heat and work. The highest value of problem solving ability obtained 26.67 from the maximum value of 100. The lowest value was 0, and the average value was 14.73. These results show that the problem-solving ability of pre-service chemistry teacher students was low. The results provide insight to researchers, and educators to develop learning or lab work on this concept

  15. HEPATIC TISSUE ENGINEERING (MODERN STATE OF THIS PROBLEM)

    OpenAIRE

    Y.S. Gulay; M.E. Krasheninnikov; M.Y. Shagidulin; N.A. Onishchenko

    2014-01-01

    In this article it was discussed the problem of creation implanted hepatic tissue engineering designs as a modern stage of complex investigation for working out bioartifi cial liver support systems. It was determined that for the positive decision of numerous biological and technological problems it is necessary: to use matrices with determined properties, which mimic properties of hepatic extracellular matrix; to use technology for stereotype sowing of these matrices by both parenchymal and ...

  16. Materials of 48. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical

    International Nuclear Information System (INIS)

    2005-01-01

    Scientific assemblies of Polish Chemical Society are the most important chemical meeting organised annually in Poland. Basic as well as application studies in all chemical branches have been extensively presented. The next subjects was proposed as scientific sessions and symposia topics: chemistry of metalorganic and supramolecular compounds; organic and bioorganic chemistry; coordination and bioinorganic chemistry; chemistry of polymers and biopolymers; physical and theoretical chemistry; catalysis; structural chemistry; analytical chemistry and environmental protection chemistry of materials and nanomaterials; technology and chemical engineering; didactics of chemistry; young scientist forum; chemistry for economy

  17. The Washington Academy of Biomedical Engineering (WABME) Quarterly Workshops: Clinical Problems and Engineering Solutions

    National Research Council Canada - National Science Library

    Wong, Kenneth

    2005-01-01

    ... University and Howard University. A prime component of WABME activities is a quarterly series of research workshops, which bring together problem-rich biomedical disciplines and solution-rich engineering and scientific disciplines...

  18. Modelling and Inverse-Modelling: Experiences with O.D.E. Linear Systems in Engineering Courses

    Science.gov (United States)

    Martinez-Luaces, Victor

    2009-01-01

    In engineering careers courses, differential equations are widely used to solve problems concerned with modelling. In particular, ordinary differential equations (O.D.E.) linear systems appear regularly in Chemical Engineering, Food Technology Engineering and Environmental Engineering courses, due to the usefulness in modelling chemical kinetics,…

  19. Reliability engineering: Old problems and new challenges

    International Nuclear Information System (INIS)

    Zio, E.

    2009-01-01

    The first recorded usage of the word reliability dates back to the 1800s, albeit referred to a person and not a technical system. Since then, the concept of reliability has become a pervasive attribute worth of both qualitative and quantitative connotations. In particular, the revolutionary social, cultural and technological changes that have occurred from the 1800s to the 2000s have contributed to the need for a rational framework and quantitative treatment of the reliability of engineered systems and plants. This has led to the rise of reliability engineering as a scientific discipline. In this paper, some considerations are shared with respect to a number of problems and challenges which researchers and practitioners in reliability engineering are facing when analyzing today's complex systems. The focus will be on the contribution of reliability to system safety and on its role within system risk analysis

  20. Hydrostatic Pressure Project: Linked-Class Problem-Based Learning in Engineering

    Science.gov (United States)

    Davis, Freddie J.; Lockwood-Cooke, Pamela; Hunt, Emily M.

    2011-01-01

    Over the last few years, WTAMU Mathematics, Engineering and Science faculty has used interdisciplinary projects as the basis for implementation of a linked-class approach to Problem-Based Learning (PBL). A project that has significant relevance to engineering statics, fluid mechanics, and calculus is the Hydrostatic Pressure Project. This project…

  1. Excel 2016 for engineering statistics a guide to solving practical problems

    CERN Document Server

    Quirk, Thomas J

    2016-01-01

    This book shows the capabilities of Microsoft Excel in teaching engineering statistics effectively. Similar to the previously published Excel 2013 for Engineering Statistics, this book is a step-by-step exercise-driven guide for students and practitioners who need to master Excel to solve practical engineering problems. If understanding statistics isn’t your strongest suit, you are not especially mathematically-inclined, or if you are wary of computers, this is the right book for you. Excel, a widely available computer program for students and managers, is also an effective teaching and learning tool for quantitative analyses in engineering courses. Its powerful computational ability and graphical functions make learning statistics much easier than in years past. However,Excel 2016 for Engineering Statistics: A Guide to Solving Practical Problems is the first book to capitalize on these improvements by teaching students and managers how to apply Excel to statistical techniques necessary in their courses and...

  2. Comparison of thermal, radical and chemical effects of EGR gases using availability analysis in dual-fuel engines at part loads

    International Nuclear Information System (INIS)

    Hosseinzadeh, A.; Khoshbakhti Saray, R.; Seyed Mahmoudi, S.M.

    2010-01-01

    Dual-fuel engines at part load inevitably suffer from lower thermal efficiency and higher emission of carbon monoxide and unburned fuel. A quasi-two-zone combustion model has been developed for studying the second-law analysis of a dual-fuel (diesel-gas) engine operating under part-load conditions. The model is composed of two divisions: a single-zone combustion model with chemical kinetics for combustion of natural gas fuel and a subsidiary zone for combustion of pilot fuel. In the latter zone, the pilot fuel is considered as a heat source derived from two superposed Wiebe's combustion functions to account for contribution of pilot fuel in ignition of gaseous fuel and the rest of the total released energy. This quasi-two-zone combustion model is able to establish the development of combustion process with time and associated important operating parameters, such as pressure, temperature, heat release rate (HRR) and species concentration. The present work is an attempt to investigate the combustion phenomenon from second-law point of view at part load and using exhaust gas recirculation (EGR) to improve the aforementioned problems. Therefore, the availability analysis is applied to the engine from inlet valve closing (IVC) until exhaust valve opening (EVO). Various availability components are identified and calculated separately with crank position. In this paper, the various availability components are identified and calculated separately with crank position. Then the different cases of EGR (chemical, radical and thermal cases) are applied to the availability analysis in dual-fuel engines at part loads. It is found that the chemical case of EGR has negative effect and in this case the unburned chemical availability is increased and the work availability decreases in comparison with baseline engine (without EGR). While the thermal and radical cases have positive effects on the availability terms especially on the unburned chemical availability and work availability

  3. Investigating and developing engineering students' mathematical modelling and problem-solving skills

    Science.gov (United States)

    Wedelin, Dag; Adawi, Tom; Jahan, Tabassum; Andersson, Sven

    2015-09-01

    How do engineering students approach mathematical modelling problems and how can they learn to deal with such problems? In the context of a course in mathematical modelling and problem solving, and using a qualitative case study approach, we found that the students had little prior experience of mathematical modelling. They were also inexperienced problem solvers, unaware of the importance of understanding the problem and exploring alternatives, and impeded by inappropriate beliefs, attitudes and expectations. Important impacts of the course belong to the metacognitive domain. The nature of the problems, the supervision and the follow-up lectures were emphasised as contributing to the impacts of the course, where students show major development. We discuss these empirical results in relation to a framework for mathematical thinking and the notion of cognitive apprenticeship. Based on the results, we argue that this kind of teaching should be considered in the education of all engineers.

  4. Abstracts of the 54. Canadian Chemical Engineering Conference : Energy for the Future

    International Nuclear Information System (INIS)

    2004-01-01

    The key energy challenges facing the chemical process industries were addressed at this international conference. Chemical engineering was shown to play a critical role in offering technical solutions to the challenges of climate change and pollution abatement on a global scale. The sessions addressed a variety of issues dealing with heavy oil processing and utilization, natural gas processing, reservoir engineering and biotechnology process systems. The presentations also addressed issues dealing with applied thermodynamics, new technologies, polymer engineering and other fundamental processes, including some used by the pulp and paper industry. The conference featured more than 500 presentations from around the world, including Canada, the United States, Asia and Europe. A total of 84 papers have been indexed separately for inclusion in this database

  5. Introduction to Problem Based Learning for Engineering Education

    DEFF Research Database (Denmark)

    Moesby, Egon; Rosenørn, Torben

    2003-01-01

    Documentation material and working papers for the workshop "Introduction to Problem Based Learning for Engineering Education" held at Chiang Mai University, Chiang Mai, Thailand, 6 - 10 October 2003. The material support the workshop where the participants go through a complete pre-planning cycle...

  6. Welding problems in nuclear power engineering

    International Nuclear Information System (INIS)

    Zubchenko, A.S.

    1986-01-01

    The problems of welding industry in nuclear power plant engineering, mainly related to the improvement of molten bath protection, are considered. Development of new materials for welding electrodes, for cladding and welding fluxes, is pointed out. Production of the following equipment is brought to a commercial level: welding heads and welding machines for branch pipe welding, anticorrosion cladding, zonal thermal treatment, electron beam welding facilities for the welding and maintenance of turbineblades, equipment for nondestructive testing of welded joints

  7. Engineering Rugged Field Assays to Detect Hazardous Chemicals Using Spore-Based Bacterial Biosensors.

    Science.gov (United States)

    Wynn, Daniel; Deo, Sapna; Daunert, Sylvia

    2017-01-01

    Bacterial whole cell-based biosensors have been genetically engineered to achieve selective and reliable detection of a wide range of hazardous chemicals. Although whole-cell biosensors demonstrate many advantages for field-based detection of target analytes, there are still some challenges that need to be addressed. Most notably, their often modest shelf life and need for special handling and storage make them challenging to use in situations where access to reagents, instrumentation, and expertise are limited. These problems can be circumvented by developing biosensors in Bacillus spores, which can be engineered to address all of these concerns. In its sporulated state, a whole cell-based biosensor has a remarkably long life span and is exceptionally resistant to environmental insult. When these spores are germinated for use in analytical techniques, they show no loss in performance, even after long periods of storage under harsh conditions. In this chapter, we will discuss the development and use of whole cell-based sensors, their adaptation to spore-based biosensors, their current applications, and future directions in the field. © 2017 Elsevier Inc. All rights reserved.

  8. Using vegetable oils and animal fats in Diesel Engines: chemical analyses and engine texts

    International Nuclear Information System (INIS)

    Marmino, I.; Verhelst, S.; Sierens, R.

    2008-01-01

    In this work, some vegetable oils (rapeseed oil, palm oil) and animal fat were tested in a Diesel engine at a range of engine spreads and torque settings, after preheating at 70 0 C. Engine performance, fuel consumption and NOx, unburnt hydrocarbons and soot emissions have been recorded. The results have been compared to those obtained with diesel fuel in the same test conditions. The oils and fats were also analyzed for their physical and chemical properties (viscosity, composition, unsaturation, heating value). NOx emissions were found to be lower for the oils than for the diesel fuel. This, combined with higher HC emissions, can probably be explained through less effective atomization due to the higher viscosity of the oils and fat. On the other hand, soot emissions were found to decrease. [it

  9. ENGINEERED BARRIER SYSTEM: PHYSICAL AND CHEMICAL ENVIRONMENT

    Energy Technology Data Exchange (ETDEWEB)

    R. Jarek

    2005-08-29

    The purpose of this model report is to describe the evolution of the physical and chemical environmental conditions within the waste emplacement drifts of the repository, including the drip shield and waste package surfaces. The resulting seepage evaporation and gas abstraction models are used in the total system performance assessment for the license application (TSPA-LA) to assess the performance of the engineered barrier system and the waste form. This report develops and documents a set of abstraction-level models that describe the engineered barrier system physical and chemical environment. Where possible, these models use information directly from other reports as input, which promotes integration among process models used for TSPA-LA. Specific tasks and activities of modeling the physical and chemical environment are included in ''Technical Work Plan for: Near-Field Environment and Transport In-Drift Geochemistry Model Report Integration'' (BSC 2005 [DIRS 173782], Section 1.2.2). As described in the technical work plan, the development of this report is coordinated with the development of other engineered barrier system reports. To be consistent with other project documents that address features, events, and processes (FEPs), Table 6.14.1 of the current report includes updates to FEP numbers and FEP subjects for two FEPs identified in the technical work plan (TWP) governing this report (BSC 2005 [DIRS 173782]). FEP 2.1.09.06.0A (Reduction-oxidation potential in EBS), as listed in Table 2 of the TWP (BSC 2005 [DIRS 173782]), has been updated in the current report to FEP 2.1.09.06.0B (Reduction-oxidation potential in Drifts; see Table 6.14-1). FEP 2.1.09.07.0A (Reaction kinetics in EBS), as listed in Table 2 of the TWP (BSC 2005 [DIRS 173782]), has been updated in the current report to FEP 2.1.09.07.0B (Reaction kinetics in Drifts; see Table 6.14-1). These deviations from the TWP are justified because they improve integration with FEPs

  10. Investigation of Problem Solving Skills among 12th Grade Engineering Students

    OpenAIRE

    Shanta, Susheela

    2017-01-01

    US competitiveness in the 21st century global economy depends on a workforce that is science, technology, engineering and mathematics (STEM) literate, and has knowledge and skills to tackle complex technological problems. In response to the need for a STEM literate workforce equipped with 21st century skills there is a push for K-12 educational reform. STEM literacy is the ability to use content knowledge and skills in science, technology, engineering and math in solving human problems in a c...

  11. The Application of Problem-Based Learning in Mechanical Engineering

    Science.gov (United States)

    Putra, Z. A.; Dewi, M.

    2018-02-01

    The course of Technology and Material Testing prepare students with the ability to do a variety of material testing in the study of mechanical engineering. Students find it difficult to understand the materials to make them unable to carry out the material testing in accordance with the purpose of study. This happens because they knowledge is not adequately supported by the competence to find and construct learning experience. In this study, quasy experiment research method with pre-post-test with control group design was used. The subjects of the study were students divided in two groups; control and experiment with twenty-two students in each group. Study result: their grades showed no difference in between the pre-test or post-test in control group, but the difference in grade existed between the pre-test and post-test in experiment group. Yet, there is no significant difference in the study result on both groups. The researcher recommend that it is necessary to develop Problem-Based Learning that suits need analysis on D3 Program for Mechanical Engineering Department at the State University of Padang, to ensure the compatibility between Model of Study and problems and need. This study aims to analyze how Problem-Based Learning effects on the course of Technology and Material Testing for the students of D3 Program of Mechanical Engineering of the State University of Padang.

  12. Metabolic engineering of Corynebacterium glutamicum for fermentative production of chemicals in biorefinery.

    Science.gov (United States)

    Baritugo, Kei-Anne; Kim, Hee Taek; David, Yokimiko; Choi, Jong-Il; Hong, Soon Ho; Jeong, Ki Jun; Choi, Jong Hyun; Joo, Jeong Chan; Park, Si Jae

    2018-05-01

    Bio-based production of industrially important chemicals provides an eco-friendly alternative to current petrochemical-based processes. Because of the limited supply of fossil fuel reserves, various technologies utilizing microbial host strains for the sustainable production of platform chemicals from renewable biomass have been developed. Corynebacterium glutamicum is a non-pathogenic industrial microbial species traditionally used for L-glutamate and L-lysine production. It is a promising species for industrial production of bio-based chemicals because of its flexible metabolism that allows the utilization of a broad spectrum of carbon sources and the production of various amino acids. Classical breeding, systems, synthetic biology, and metabolic engineering approaches have been used to improve its applications, ranging from traditional amino-acid production to modern biorefinery systems for production of value-added platform chemicals. This review describes recent advances in the development of genetic engineering tools and techniques for the establishment and optimization of metabolic pathways for bio-based production of major C2-C6 platform chemicals using recombinant C. glutamicum.

  13. Perm State University HPC-hardware and software services: capabilities for aircraft engine aeroacoustics problems solving

    Science.gov (United States)

    Demenev, A. G.

    2018-02-01

    The present work is devoted to analyze high-performance computing (HPC) infrastructure capabilities for aircraft engine aeroacoustics problems solving at Perm State University. We explore here the ability to develop new computational aeroacoustics methods/solvers for computer-aided engineering (CAE) systems to handle complicated industrial problems of engine noise prediction. Leading aircraft engine engineering company, including “UEC-Aviadvigatel” JSC (our industrial partners in Perm, Russia), require that methods/solvers to optimize geometry of aircraft engine for fan noise reduction. We analysed Perm State University HPC-hardware resources and software services to use efficiently. The performed results demonstrate that Perm State University HPC-infrastructure are mature enough to face out industrial-like problems of development CAE-system with HPC-method and CFD-solvers.

  14. Metabolic Engineering of Oleaginous Yeasts for Production of Fuels and Chemicals

    Directory of Open Access Journals (Sweden)

    Shuobo Shi

    2017-11-01

    Full Text Available Oleaginous yeasts have been increasingly explored for production of chemicals and fuels via metabolic engineering. Particularly, there is a growing interest in using oleaginous yeasts for the synthesis of lipid-related products due to their high lipogenesis capability, robustness, and ability to utilize a variety of substrates. Most of the metabolic engineering studies in oleaginous yeasts focused on Yarrowia that already has plenty of genetic engineering tools. However, recent advances in systems biology and synthetic biology have provided new strategies and tools to engineer those oleaginous yeasts that have naturally high lipid accumulation but lack genetic tools, such as Rhodosporidium, Trichosporon, and Lipomyces. This review highlights recent accomplishments in metabolic engineering of oleaginous yeasts and recent advances in the development of genetic engineering tools in oleaginous yeasts within the last 3 years.

  15. Engineering microbial chemical factories to produce renewable "biomonomers".

    Science.gov (United States)

    Adkins, Jake; Pugh, Shawn; McKenna, Rebekah; Nielsen, David R

    2012-01-01

    By applying metabolic engineering tools and strategies to engineer synthetic enzyme pathways, the number and diversity of commodity and specialty chemicals that can be derived directly from renewable feedstocks is rapidly and continually expanding. This of course includes a number of monomer building-block chemicals that can be used to produce replacements to many conventional plastic materials. This review aims to highlight numerous recent and important advancements in the microbial production of these so-called "biomonomers." Relative to naturally-occurring renewable bioplastics, biomonomers offer several important advantages, including improved control over the final polymer structure and purity, the ability to synthesize non-natural copolymers, and allowing products to be excreted from cells which ultimately streamlines downstream recovery and purification. To highlight these features, a handful of biomonomers have been selected as illustrative examples of recent works, including polyamide monomers, styrenic vinyls, hydroxyacids, and diols. Where appropriate, examples of their industrial penetration to date and end-product uses are also highlighted. Novel biomonomers such as these are ultimately paving the way toward new classes of renewable bioplastics that possess a broader diversity of properties than ever before possible.

  16. The main chemical safety problems in main process of nuclear fuel reprocessing plant

    International Nuclear Information System (INIS)

    Song Fengli; Zhao Shangui; Liu Xinhua; Zhang Chunlong; Lu Dan; Liu Yuntao; Yang Xiaowei; Wang Shijun

    2014-01-01

    There are many chemical reactions in the aqueous process of nuclear fuel reprocessing. The reaction conditions and the products are different so that the chemical safety problems are different. In the paper the chemical reactions in the aqueous process of nuclear fuel reprocessing are described and the main chemical safety problems are analyzed. The reference is offered to the design and accident analysis of the nuclear fuel reprocessing plant. (authors)

  17. Engineering and Evolution of Saccharomyces cerevisiae to Produce Biofuels and Chemicals.

    Science.gov (United States)

    Turner, Timothy L; Kim, Heejin; Kong, In Iok; Liu, Jing-Jing; Zhang, Guo-Chang; Jin, Yong-Su

    To mitigate global climate change caused partly by the use of fossil fuels, the production of fuels and chemicals from renewable biomass has been attempted. The conversion of various sugars from renewable biomass into biofuels by engineered baker's yeast (Saccharomyces cerevisiae) is one major direction which has grown dramatically in recent years. As well as shifting away from fossil fuels, the production of commodity chemicals by engineered S. cerevisiae has also increased significantly. The traditional approaches of biochemical and metabolic engineering to develop economic bioconversion processes in laboratory and industrial settings have been accelerated by rapid advancements in the areas of yeast genomics, synthetic biology, and systems biology. Together, these innovations have resulted in rapid and efficient manipulation of S. cerevisiae to expand fermentable substrates and diversify value-added products. Here, we discuss recent and major advances in rational (relying on prior experimentally-derived knowledge) and combinatorial (relying on high-throughput screening and genomics) approaches to engineer S. cerevisiae for producing ethanol, butanol, 2,3-butanediol, fatty acid ethyl esters, isoprenoids, organic acids, rare sugars, antioxidants, and sugar alcohols from glucose, xylose, cellobiose, galactose, acetate, alginate, mannitol, arabinose, and lactose.

  18. Investigating and Developing Engineering Students' Mathematical Modelling and Problem-Solving Skills

    Science.gov (United States)

    Wedelin, Dag; Adawi, Tom; Jahan, Tabassum; Andersson, Sven

    2015-01-01

    How do engineering students approach mathematical modelling problems and how can they learn to deal with such problems? In the context of a course in mathematical modelling and problem solving, and using a qualitative case study approach, we found that the students had little prior experience of mathematical modelling. They were also inexperienced…

  19. Excel 2013 for engineering statistics a guide to solving practical problems

    CERN Document Server

    Quirk, Thomas J

    2015-01-01

    This is the first book to show the capabilities of Microsoft Excel to teach engineering statistics effectively.  It is a step-by-step exercise-driven guide for students and practitioners who need to master Excel to solve practical engineering problems.  If understanding statistics isn’t your strongest suit, you are not especially mathematically-inclined, or if you are wary of computers, this is the right book for you. Excel, a widely available computer program for students and managers, is also an effective teaching and learning tool for quantitative analyses in engineering courses.  Its powerful computational ability and graphical functions make learning statistics much easier than in years past.  However, Excel 2013 for Engineering Statistics: A Guide to Solving Practical Problems is the first book to capitalize on these improvements by teaching students and managers how to apply Excel to statistical techniques necessary in their courses and work. Each chapter explains statistical formulas and directs...

  20. Teaching-Learning-Based Optimization with Learning Enthusiasm Mechanism and Its Application in Chemical Engineering

    Directory of Open Access Journals (Sweden)

    Xu Chen

    2018-01-01

    Full Text Available Teaching-learning-based optimization (TLBO is a population-based metaheuristic search algorithm inspired by the teaching and learning process in a classroom. It has been successfully applied to many scientific and engineering applications in the past few years. In the basic TLBO and most of its variants, all the learners have the same probability of getting knowledge from others. However, in the real world, learners are different, and each learner’s learning enthusiasm is not the same, resulting in different probabilities of acquiring knowledge. Motivated by this phenomenon, this study introduces a learning enthusiasm mechanism into the basic TLBO and proposes a learning enthusiasm based TLBO (LebTLBO. In the LebTLBO, learners with good grades have high learning enthusiasm, and they have large probabilities of acquiring knowledge from others; by contrast, learners with bad grades have low learning enthusiasm, and they have relative small probabilities of acquiring knowledge from others. In addition, a poor student tutoring phase is introduced to improve the quality of the poor learners. The proposed method is evaluated on the CEC2014 benchmark functions, and the computational results demonstrate that it offers promising results compared with other efficient TLBO and non-TLBO algorithms. Finally, LebTLBO is applied to solve three optimal control problems in chemical engineering, and the competitive results show its potential for real-world problems.

  1. Using Ontological Engineering to Overcome AI-ED Problems: Contribution, Impact and Perspectives

    Science.gov (United States)

    Mizoguchi, Riichiro; Bourdeau, Jacqueline

    2016-01-01

    This article reflects on the ontology engineering methodology discussed by the paper entitled "Using Ontological Engineering to Overcome AI-ED Problems" published in this journal in 2000. We discuss the achievements obtained in the last 10 years, the impact of our work as well as recent trends and perspectives in ontology engineering for…

  2. Engineering problems of tandem-mirror reactors

    International Nuclear Information System (INIS)

    Moir, R.W.; Barr, W.L.; Boghosian, B.M.

    1981-01-01

    We have completed a comparative evaluation of several end plug configurations for tandem mirror fusion reactors with thermal barriers. The axi-cell configuration has been selected for further study and will be the basis for a detailed conceptual design study to be carried out over the next two years. The axi-cell end plug has a simple mirror cell produced by two circular coils followed by a transition coil and a yin-yang pair, which provides for MHD stability. This paper discusses some of the many engineering problems facing the designer. We estimated the direct cost to be 2$/W/sub e/. Assuming total (direct and indirect) costs to be twice this number, we need to reduce total costs by factors between 1.7 and 2.3 to compete with future LWRs levelized cost of electricity. These reductions may be possible by designing magnets producing over 20T made possible by use of combinations of superconducting and normal conducting coils as well as improvements in performance and cost of neutral beam and microwave power systems. Scientific and technological understanding and innovation are needed in the area of thermal barrier pumping - a process by which unwanted particles are removed (pumped) from certain regions of velocity and real space in the end plug. Removal of exhaust fuel ions, fusion ash and impurities by action of a halo plasma and plasma dump in the mirror end region is another challenging engineering problem discussed in this paper

  3. Use of the LITEE Lorn Manufacturing Case Study in a Senior Chemical Engineering Unit Operations Laboratory

    Science.gov (United States)

    Abraham, Nithin Susan; Abulencia, James Patrick

    2011-01-01

    This study focuses on the effectiveness of incorporating the Laboratory for Innovative Technology and Engineering Education (LITEE) Lorn Manufacturing case into a senior level chemical engineering unit operations course at Manhattan College. The purpose of using the case study is to demonstrate the relevance of ethics to chemical engineering…

  4. Applying chemical engineering concepts to non-thermal plasma reactors

    Science.gov (United States)

    Pedro AFFONSO, NOBREGA; Alain, GAUNAND; Vandad, ROHANI; François, CAUNEAU; Laurent, FULCHERI

    2018-06-01

    Process scale-up remains a considerable challenge for environmental applications of non-thermal plasmas. Undersanding the impact of reactor hydrodynamics in the performance of the process is a key step to overcome this challenge. In this work, we apply chemical engineering concepts to analyse the impact that different non-thermal plasma reactor configurations and regimes, such as laminar or plug flow, may have on the reactor performance. We do this in the particular context of the removal of pollutants by non-thermal plasmas, for which a simplified model is available. We generalise this model to different reactor configurations and, under certain hypotheses, we show that a reactor in the laminar regime may have a behaviour significantly different from one in the plug flow regime, often assumed in the non-thermal plasma literature. On the other hand, we show that a packed-bed reactor behaves very similarly to one in the plug flow regime. Beyond those results, the reader will find in this work a quick introduction to chemical reaction engineering concepts.

  5. Understanding performance properties of chemical engines under a trade-off optimization: Low-dissipation versus endoreversible model

    Science.gov (United States)

    Tang, F. R.; Zhang, Rong; Li, Huichao; Li, C. N.; Liu, Wei; Bai, Long

    2018-05-01

    The trade-off criterion is used to systemically investigate the performance features of two chemical engine models (the low-dissipation model and the endoreversible model). The optimal efficiencies, the dissipation ratios, and the corresponding ratios of the dissipation rates for two models are analytically determined. Furthermore, the performance properties of two kinds of chemical engines are precisely compared and analyzed, and some interesting physics is revealed. Our investigations show that the certain universal equivalence between two models is within the framework of the linear irreversible thermodynamics, and their differences are rooted in the different physical contexts. Our results can contribute to a precise understanding of the general features of chemical engines.

  6. Effects of chemical equilibrium on turbine engine performance for various fuels and combustor temperatures

    Science.gov (United States)

    Tran, Donald H.; Snyder, Christopher A.

    1992-01-01

    A study was performed to quantify the differences in turbine engine performance with and without the chemical dissociation effects for various fuel types over a range of combustor temperatures. Both turbojet and turbofan engines were studied with hydrocarbon fuels and cryogenic, nonhydrocarbon fuels. Results of the study indicate that accuracy of engine performance decreases when nonhydrocarbon fuels are used, especially at high temperatures where chemical dissociation becomes more significant. For instance, the deviation in net thrust for liquid hydrogen fuel can become as high as 20 percent at 4160 R. This study reveals that computer central processing unit (CPU) time increases significantly when dissociation effects are included in the cycle analysis.

  7. Chemical Engineering Division annual technical report, 1980

    International Nuclear Information System (INIS)

    Burris, L.; Webster, D.S.; Barney, D.L.; Cafasso, F.A.; Steindler, M.J.

    1981-06-01

    Highlights of the Chemical Engineering (CEN) Division's activities during 1980 are presented. In this period, CEN conducted research and development in the following areas: (1) rechargeable lithium-aluminum/iron sulfide batteries for electric vehicles and other applications; (2) ambient-temperature batteries - improved lead-acid, nickel/zinc, and nickel/iron - for electric vehicles; (3) energy-efficient industrial electrochemical processes; (4) molten carbonate fuel cells for use by electric utilities; (5) coal technology, mainly fluidized-bed combustion of coal in the presence of SO 2 sorbent of limestone; (6) heat- and seed-recovery technology for open-cycle magnetohydrodynamic systems; (7) solar energy collectors and thermal energy storage; (8) fast breeder reactor chemistry research - chemical support of reactor safety studies, chemistry of irradiated fuels, and sodium technology; (9) fuel cycle technology - management of nuclear wastes, reprocessing of nuclear fuels, and proof-of-breeding studies for the Light Water Breeder Reactor; and (10) magnetic fusion research - systems analysis and engineering experimentation, materials research, and neutron dosimetry and damage analysis. The CEN Division also has a basic energy sciences program, which includes experimental and theoretical research on (1) the catalytic hydrogenation of carbon monoxide and methanol homologation, (2) the thermodynamic properties of a wide variety of inorganic and organic materials, (3) significant mechanisms for the formation of atmospheric sulfate and nitrogen-bearing aerosols, (4) processes occurring at electrodes and in electrolytes, and (5) the physical properties of salt vapors. In addition, the Division operated the Central Analytical Chemistry Laboratory

  8. Introducing future engineers to sustainable ecology problems: a case study

    Science.gov (United States)

    Filipkowski, A.

    2011-12-01

    The problem of Earth environmental destruction by human activities is becoming dangerous. Engineers responsible for the production of any goods should be well aware of the negative influence of their activities on the state of the planet. This is why the understanding of ecological problems is essential for people responsible for production and industrial design. The energy, which they consume, is increasing the greenhouse effect and the waste poisons the environment. So far, most courses on ecology are offered to specialists in environmental engineering. These courses are filled with many details. The Warsaw Academy of Computer Science, Management and Administration teaches students in the direction of management and production engineering. Upon completion, the students receive the degree of 'engineer'. Their future work will mainly concern management of different types of industrial enterprises and they will be responsible for organising it in such a way as to avoid a dangerous contribution to environmental pollution and climate change. This is why it was decided to introduce a new course entitled 'Principles of Ecology and Environmental Management'. This course is quite broad, concerning almost all technical, law and organisational aspects of the problem. The presentation is made in a spectacular way, aiming to convince students that their future activity must be environmentally friendly. It contains information about international activities in ecology, legal aspects concerning pollution, technical and information methods of monitoring and, finally, the description of 'green' solutions. Altogether, 27 hours of lectures and 15 hours of discussions and students' presentations complete the course. Details of this course are described in this paper.

  9. A computational environment for creating and testing reduced chemical kinetic mechanisms

    Energy Technology Data Exchange (ETDEWEB)

    Montgomery, C.J.; Swensen, D.A.; Harding, T.V.; Cremer, M.A.; Bockelie, M.J. [Reaction Engineering International, Salt Lake City, UT (USA)

    2002-02-01

    This paper describes software called computer assisted reduced mechanism problem solving environment (CARM-PSE) that gives the engineer the ability to rapidly set up, run and examine large numbers of problems comparing detailed and reduced (approximate) chemistry. CARM-PSE integrates the automatic chemical mechanism reduction code CARM and the codes that simulate perfectly stirred reactors and plug flow reactors into a user-friendly computational environment. CARM-PSE gives the combustion engineer the ability to easily test chemical approximations over many hundreds of combinations of inputs in a multidimensional parameter space. The demonstration problems compare detailed and reduced chemical kinetic calculations for methane-air combustion, including nitrogen oxide formation, in a stirred reactor and selective non-catalytic reduction of NOx, in coal combustion flue gas.

  10. Materials of 47. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry. Volume 3

    International Nuclear Information System (INIS)

    2004-01-01

    Scientific assemblies of Polish Chemical Society are the most important chemical meeting organised annually in Poland. Basic as well as application studies in all chemical branches have been extensively presented. The next subjects was proposed as scientific sessions and symposia topics: organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, technology and chemical engineering, polymer chemistry, solid state chemistry, catalysis, biological chemistry, chemistry and technology of coal, environmental protection, didactics of chemistry, history of chemistry, young scientist forum

  11. The Problem of Whistleblowing in Engineering Ethics

    Science.gov (United States)

    Ohishi, Toshihiro

    The purpose of this paper is to clarify the features of whistleblowing by considering the arguments about whistleblowing in engineering ethics. First, I analyze the concept of ‘whistleblowing’ by defining the word as clearly as possible. Second, I examine the standard justification theory of whistleblowing by showing the problems of the theory. Finally, I analyze the dilemma about whistleblowing by revealing a prospective whistleblower‧s struggle to choose moral value or non-moral value.

  12. The Chemical Engineer's Toolbox: A Glass Box Approach to Numerical Problem Solving

    Science.gov (United States)

    Coronell, Daniel G.; Hariri, M. Hossein

    2009-01-01

    Computer programming in undergraduate engineering education all too often begins and ends with the freshman programming course. Improvements in computer technology and curriculum revision have improved this situation, but often at the expense of the students' learning due to the use of commercial "black box" software. This paper describes the…

  13. Stirling engines for biomass – what is the problem?

    DEFF Research Database (Denmark)

    Carlsen, Henrik

    2005-01-01

    The External combustion of the Stirling engine makes it very attractive for small-scale Combined Heat and Power (CHP) plants using bio-fuels. Especially wood chips are an attractive fuel because of the high melting point and the low content of ash. Unfortunately, it is more complicated than...... expected to use bio-fuels for a Stirling engine. The high temperature in the hot heat exchanger transferring heat from the combustion to the Stirling engine combined with the low heating value of the fuel reduce the obtainable efficiency of the plant. The limitations of the combustion temperature in order...... to avoid melted ash in the combustion chamber decrease the obtainable efficiency even further. If a Stirling engine, which has an efficiency of 28,5% using natural gas, is converted into utilization of bio-fuel, the efficiency will decrease to 17,5%. Another problem for utilization of bio-fuels in Stirling...

  14. Introduction to Chemical Engineering Reactor Analysis: A Web-Based Reactor Design Game

    Science.gov (United States)

    Orbey, Nese; Clay, Molly; Russell, T.W. Fraser

    2014-01-01

    An approach to explain chemical engineering through a Web-based interactive game design was developed and used with college freshman and junior/senior high school students. The goal of this approach was to demonstrate how to model a lab-scale experiment, and use the results to design and operate a chemical reactor. The game incorporates both…

  15. Rurality as an Asset for Inclusive Teaching in Chemical Engineering

    Science.gov (United States)

    Gomez, Jamie; Svihla, Vanessa

    2018-01-01

    We developed and tested a pedagogical strategy--asset-based design challenges--to enhance diversity in early chemical engineering coursework. Using qualitative methods, we found first-year students justified high-cost solutions with ethical arguments; teams that included rural expertise argued instead for economically-viable solutions. In the…

  16. Testing foreign language impact on engineering students' scientific problem-solving performance

    Science.gov (United States)

    Tatzl, Dietmar; Messnarz, Bernd

    2013-12-01

    This article investigates the influence of English as the examination language on the solution of physics and science problems by non-native speakers in tertiary engineering education. For that purpose, a statistically significant total number of 96 students in four year groups from freshman to senior level participated in a testing experiment in the Degree Programme of Aviation at the FH JOANNEUM University of Applied Sciences, Graz, Austria. Half of each test group were given a set of 12 physics problems described in German, the other half received the same set of problems described in English. It was the goal to test linguistic reading comprehension necessary for scientific problem solving instead of physics knowledge as such. The results imply that written undergraduate English-medium engineering tests and examinations may not require additional examination time or language-specific aids for students who have reached university-entrance proficiency in English as a foreign language.

  17. Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals.

    Science.gov (United States)

    Borodina, Irina; Nielsen, Jens

    2014-05-01

    Yeast Saccharomyces cerevisiae is an important industrial host for production of enzymes, pharmaceutical and nutraceutical ingredients and recently also commodity chemicals and biofuels. Here, we review the advances in modeling and synthetic biology tools and how these tools can speed up the development of yeast cell factories. We also present an overview of metabolic engineering strategies for developing yeast strains for production of polymer monomers: lactic, succinic, and cis,cis-muconic acids. S. cerevisiae has already firmly established itself as a cell factory in industrial biotechnology and the advances in yeast strain engineering will stimulate development of novel yeast-based processes for chemicals production. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. NNEPEQ: Chemical equilibrium version of the Navy/NASA Engine Program

    Science.gov (United States)

    Fishbach, Laurence H.; Gordon, Sanford

    1988-01-01

    The Navy NASA Engine Program, NNEP, currently is in use at a large number of government agencies, commercial companies and universities. This computer code has bee used extensively to calculate the design and off-design (matched) performance of a broad range of turbine engines, ranging from subsonic turboprops to variable cycle engines for supersonic transports. Recently, there has been increased interest in applications for which NNEP was not capable of simulating, namely, high Mach applications, alternate fuels including cryogenics, and cycles such as the gas generator air-turbo-rocker (ATR). In addition, there is interest in cycles employing ejectors such as for military fighters. New engine component models had to be created for incorporation into NNEP, and it was found necessary to include chemical dissociation effects of high temperature gases. The incorporation of these extended capabilities into NNEP is discussed and some of the effects of these changes are illustrated.

  19. NNEPEQ - Chemical equilibrium version of the Navy/NASA Engine Program

    Science.gov (United States)

    Fishbach, L. H.; Gordon, S.

    1989-01-01

    The Navy NASA Engine Program, NNEP, currently is in use at a large number of government agencies, commercial companies and universities. This computer code has been used extensively to calculate the design and off-design (matched) performance of a broad range of turbine engines, ranging from subsonic turboprops to variable cycle engines for supersonic transports. Recently, there has been increased interest in applications for which NNEP was not capable of simulating, namely, high Mach applications, alternate fuels including cryogenics, and cycles such as the gas generator air-turbo-rocker (ATR). In addition, there is interest in cycles employing ejectors such as for military fighters. New engine component models had to be created for incorporation into NNEP, and it was found necessary to include chemical dissociation effects of high temperature gases. The incorporation of these extended capabilities into NNEP is discussed and some of the effects of these changes are illustrated.

  20. Abstracts Book of Jubilee Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry

    International Nuclear Information System (INIS)

    2000-01-01

    Scientific Assemblies of Polish Chemical Society and Association of Engineers and Technicians of Chemical Industry are most important chemical discussion forum organised annually in Poland. Basic as well as application studies in all chemical branches have been extensively presented. The next subjects was proposed as sections and symposia topics: organic chemistry, physical chemistry (chemical kinetics, catalysis, thermodynamics), membranes and membrane processes, biological chemistry, biotechnology, metalorganic compounds and complexes, polymer chemistry, crystallochemical study, spectroscopy in nowadays chemistry, supramolecular chemistry, chemistry and technology of coal, high-energetic materials, environment protection, didactics in chemistry, radiation chemistry, photochemistry, electrochemistry, chemistry and technology of carbohydrates, theoretical and computer chemistry, young scientists forum, history of chemistry

  1. Correlation between electrical, mechanical and chemical properties of fresh and used aircraft engine oils

    Science.gov (United States)

    Gajewski, Juliusz B.; Głogowski, Marek J.; Paszkowski, Maciej; Czarnik-Matusewicz, Bogusława

    2011-06-01

    In this paper the results are presented of measurements of electrical, mechanical and chemical properties of fresh and used aircraft engine oils. Oils were used in a four-stroke aircraft engine and their samples were taken after the 50-hour work of the engine. The resistivity, permittivity and viscosity of oils were measured as a function of temperature. Additionally, some measurements of the absorbance spectra and size of particles contained in the oils were carried out. The significant reduction in the resistivity of the used Total oil was observed. The relative permittivity of both used oils was slightly increased. The oil's relative viscosity depends on temperature of oil and given time that elapsed from the very first moment when the shear force was applied in a rheometer. The results obtained allowed one to identify more precisely the chemical and physico-chemical interactions occurring in the tested samples, as compared with a typical infrared spectroscopy.

  2. Correlation between electrical, mechanical and chemical properties of fresh and used aircraft engine oils

    International Nuclear Information System (INIS)

    Gajewski, Juliusz B; Glogowski, Marek J; Paszkowski, Maciej; Czarnik-Matusewicz, Boguslawa

    2011-01-01

    In this paper the results are presented of measurements of electrical, mechanical and chemical properties of fresh and used aircraft engine oils. Oils were used in a four-stroke aircraft engine and their samples were taken after the 50-hour work of the engine. The resistivity, permittivity and viscosity of oils were measured as a function of temperature. Additionally, some measurements of the absorbance spectra and size of particles contained in the oils were carried out. The significant reduction in the resistivity of the used Total oil was observed. The relative permittivity of both used oils was slightly increased. The oil's relative viscosity depends on temperature of oil and given time that elapsed from the very first moment when the shear force was applied in a rheometer. The results obtained allowed one to identify more precisely the chemical and physico-chemical interactions occurring in the tested samples, as compared with a typical infrared spectroscopy.

  3. Fueling Chemical Engineering Concepts with Biodiesel Production: A Professional Development Experience for High School Pre-Service Teachers

    Science.gov (United States)

    Gupta, Anju

    2015-01-01

    This one-day workshop for pre-service teachers was aimed at implementing a uniquely designed and ready-to-implement chemical engineering curriculum in high school coursework. This educational and professional development opportunity introduced: 1) chemical engineering curriculum and career opportunities, 2) basic industrial processes and flow…

  4. Online Data Resources in Chemical Engineering Education: Impact of the Uncertainty Concept for Thermophysical Properties

    Science.gov (United States)

    Kim, Sun Hyung; Kang, Jeong Won; Kroenlein, Kenneth; Magee, Joseph W.; Diky, Vladimir; Muzny, Chris D.; Kazakov, Andrei F.; Chirico, Robert D.; Frenkel, Michael

    2013-01-01

    We review the concept of uncertainty for thermophysical properties and its critical impact for engineering applications in the core courses of chemical engineering education. To facilitate the translation of developments to engineering education, we employ NIST Web Thermo Tables to furnish properties data with their associated expanded…

  5. Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

    DEFF Research Database (Denmark)

    Hudson, Brian D; Christiansen, Elisabeth; Tikhonova, Irina G

    2012-01-01

    When it is difficult to develop selective ligands within a family of related G-protein-coupled receptors (GPCRs), chemically engineered receptors activated solely by synthetic ligands (RASSLs) are useful alternatives for probing receptor function. In the present work, we explored whether a RASSL...... on this receptor and demonstrates that exploitation of pharmacological variation between species orthologs is a powerful method to generate novel chemically engineered GPCRs.-Hudson, B. D., Christiansen, E., Tikhonova, I. G., Grundmann, M., Kostenis, E., Adams, D. R., Ulven, T., Milligan, G. Chemically engineering...

  6. High-Performance Liquid Chromatography in the Undergraduate Chemical Engineering Laboratory

    Science.gov (United States)

    Frey, Douglas D.; Guo, Hui; Karnik, Nikhila

    2013-01-01

    This article describes the assembly of a simple, low-cost, high-performance liquid chromatography (HPLC) system and its use in the undergraduate chemical engineering laboratory course to perform simple experiments. By interpreting the results from these experiments students are able to gain significant experience in the general method of…

  7. Metabolic engineering of strains: from industrial-scale to lab-scale chemical production.

    Science.gov (United States)

    Sun, Jie; Alper, Hal S

    2015-03-01

    A plethora of successful metabolic engineering case studies have been published over the past several decades. Here, we highlight a collection of microbially produced chemicals using a historical framework, starting with titers ranging from industrial scale (more than 50 g/L), to medium-scale (5-50 g/L), and lab-scale (0-5 g/L). Although engineered Escherichia coli and Saccharomyces cerevisiae emerge as prominent hosts in the literature as a result of well-developed genetic engineering tools, several novel native-producing strains are gaining attention. This review catalogs the current progress of metabolic engineering towards production of compounds such as acids, alcohols, amino acids, natural organic compounds, and others.

  8. Solved and unsolved problems of chemical graph theory

    International Nuclear Information System (INIS)

    Trinajstic, N.; Klein, D.J.; Randic, M.

    1986-01-01

    The development of several novel graph theoretical concepts and their applications in different branches of chemistry are reviewed. After a few introductory remarks they follow with an outline of selected important graph theoretical invariants, introducing some new results and indicating some open problems. They continue with discussing the problem of graph characterization and construction of graphs of chemical interest, with a particular emphasis on large systems. Finally they consider various problems and difficulties associated with special subgraphs, including subgraphs representing Kekule valence structures. The paper ends with a brief review of structure-property and structure-activity correlations, the topic which is one of prime motivations for application of graph theory to chemistry

  9. Mechanical engineering problems in the TFTR neutral beam system

    International Nuclear Information System (INIS)

    Cannon, D.D.; Bryant, E.H.; Johnson, R.L.; Kim, J.; Queen, C.C.; Schilling, G.

    1975-01-01

    A conceptual design of a prototype beam line for the TFTR Neutral Beam System has been developed. The basic components have been defined, cost estimates prepared, and the necessary development programs identified. Four major mechanical engineering problems, potential solutions and the required development programs are discussed

  10. A Case Study: Problem-Based Learning for Civil Engineering Students in Transportation Courses

    Science.gov (United States)

    Ahern, A. A.

    2010-01-01

    This paper describes two case studies where problem-based learning (PBL) has been introduced to undergraduate civil engineering students in University College Dublin. PBL has recently been put in place in the penultimate and final year transport engineering classes in the civil engineering degree in University College Dublin. In this case study,…

  11. Engineering Microbial Chemical Factories to Produce Renewable ‘Biomonomers’

    Directory of Open Access Journals (Sweden)

    Jake eAdkins

    2012-08-01

    Full Text Available By applying metabolic engineering tools and strategies to engineer synthetic enzyme pathways, the number and diversity of commodity and specialty chemicals that can be derived directly from renewable feedstocks is rapidly and continually expanding. This of course includes a number of monomer building-block chemicals that can be used to produce replacements to many conventional plastic materials. This review aims to highlight numerous recent and important advancements in the microbial production of these so-called ‘biomonomers’. Relative to naturally-occurring renewable bioplastics, biomonomers offer several important advantages, including improved control over the final polymer structure and purity, the ability to synthesize non-natural copolymers, and allowing products to be excreted from cells which ultimately streamlines downstream recovery and purification. To highlight these features, a handful of biomonomers have been selected as illustrative examples of recent works, including polyamide monomers, styrenic vinyls, hydroxyacids, and diols. Where appropriate, examples of their industrial penetration to date and end-product uses are also highlighted. Novel biomonomers such as these are ultimately paving the way towards new classes of renewable bioplastics that possess a broader diversity of properties than ever before possible.

  12. Engineering microbial chemical factories to produce renewable “biomonomers”

    Science.gov (United States)

    Adkins, Jake; Pugh, Shawn; McKenna, Rebekah; Nielsen, David R.

    2012-01-01

    By applying metabolic engineering tools and strategies to engineer synthetic enzyme pathways, the number and diversity of commodity and specialty chemicals that can be derived directly from renewable feedstocks is rapidly and continually expanding. This of course includes a number of monomer building-block chemicals that can be used to produce replacements to many conventional plastic materials. This review aims to highlight numerous recent and important advancements in the microbial production of these so-called “biomonomers.” Relative to naturally-occurring renewable bioplastics, biomonomers offer several important advantages, including improved control over the final polymer structure and purity, the ability to synthesize non-natural copolymers, and allowing products to be excreted from cells which ultimately streamlines downstream recovery and purification. To highlight these features, a handful of biomonomers have been selected as illustrative examples of recent works, including polyamide monomers, styrenic vinyls, hydroxyacids, and diols. Where appropriate, examples of their industrial penetration to date and end-product uses are also highlighted. Novel biomonomers such as these are ultimately paving the way toward new classes of renewable bioplastics that possess a broader diversity of properties than ever before possible. PMID:22969753

  13. Toward systems metabolic engineering of Aspergillus and Pichia species for the production of chemicals and biofuels

    DEFF Research Database (Denmark)

    Caspeta, Luis; Nielsen, Jens

    2013-01-01

    trends in systems biology of Aspergillus and Pichia species, highlighting the relevance of these developments for systems metabolic engineering of these organisms for the production of hydrolytic enzymes, biofuels and chemicals from biomass. Metabolic engineering is moving from traditional methods...... for the production of hydrolytic enzymes, biofuels and chemicals from biomass. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim....

  14. Analysis of forward and inverse problems in chemical dynamics and spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Rabitz, H. [Princeton Univ., NJ (United States)

    1993-12-01

    The overall scope of this research concerns the development and application of forward and inverse analysis tools for problems in chemical dynamics and chemical kinetics. The chemical dynamics work is specifically associated with relating features in potential surfaces and resultant dynamical behavior. The analogous inverse research aims to provide stable algorithms for extracting potential surfaces from laboratory data. In the case of chemical kinetics, the focus is on the development of systematic means to reduce the complexity of chemical kinetic models. Recent progress in these directions is summarized below.

  15. Chemical problems associated with reprocessing

    International Nuclear Information System (INIS)

    Chesne, A.

    1981-09-01

    This paper is an attempt to pinpoint the chemical problems raised by the reprocessing of oxide base fuels. Taking the reprocessing of slightly irradiated metallic fuels as a reference, for which long experience has been gained, a review is made of the various stages of the Purex process, in which the increase in mass and activity of the actinides and fission products engenders constraints related to the recovery of fissile materials, their purification, the release rate and, in general, the operation of the installations. The following subjects are discussed: dissolution from the standpoint of dissolution residues and iodine trapping, extraction cycles with respect to the behavior of ruthenium, neptunium, plutonium, technetium and palladium, the recycling of medium activity wastes

  16. Fluid flow for chemical and process engineers

    CERN Document Server

    Holland, F

    1995-01-01

    This major new edition of a popular undergraduate text covers topics of interest to chemical engineers taking courses on fluid flow. These topics include non-Newtonian flow, gas-liquid two-phase flow, pumping and mixing. It expands on the explanations of principles given in the first edition and is more self-contained. Two strong features of the first edition were the extensive derivation of equations and worked examples to illustrate calculation procedures. These have been retained. A new extended introductory chapter has been provided to give the student a thorough basis to understand the methods covered in subsequent chapters.

  17. Environmental protection, a task of chemical engineering

    Energy Technology Data Exchange (ETDEWEB)

    Schlachter, H

    1980-12-01

    The environmental burden in air and water in Germany is surveyed. The terms 'eco-unobjectionable technology' and 'disposal technology' are then considered with the aid of examples. These are fundamental chemical engineering approaches for reducing or eliminating environmental burdens due to industrial production processes. 'Eco-unobjectionable processes' are those in which undesired pollutants are not even formed, i.e. when possible emissions are eliminated at source. If this is only partly possible, or impossible, then disposal measures are adopted. This means removal of unavoidable pollutants from waste gases and waste water, and the disposal of other wastes.

  18. Some radiation chemical aspects of nuclear engineering

    International Nuclear Information System (INIS)

    Pikaev, A.K.; Kabakchi, S.A.; Egorov, G.F.

    1988-01-01

    Some radiation chemical aspects of nuclear engineering are discussed (predominantly on the base of the works performed in the Soviet Union). The data on the influence of temperature within the range of 0-300 0 C on the yields of water radiolysis products are considered. The results obtained from the study of reactivity of actinide ions towards inorganic free radicals in acid aqueous solutions are summarized. The information on composition and properties of the products of radiolytic transformations of different extragents and diluents and on their influence on the behaviour of extraction systems during processing of irradiated nuclear fuel is presented. (author)

  19. NON-INVASIVE INVERSE PROBLEM IN CIVIL ENGINEERING

    Directory of Open Access Journals (Sweden)

    Jan Havelka

    2017-11-01

    Full Text Available In this contribution we focus on recovery of spatial distribution of material parameters utilizing only non-invasive boundary measurements. Such methods has gained its importance as imaging techniques in medicine, geophysics or archaeology. We apply similar principles for non-stationary heat transfer in civil engineering. In oppose to standard technique which rely on external loading devices, we assume the natural fluctuation of temperature throughout day and night can provide sufficient information to recover the underlying material parameters. The inverse problem was solved by a modified regularised Gauss-Newton iterative scheme and the underlying forward problem is solved with a finite element space-time discretisation. We show a successful reconstruction of material parameters on a synthetic example with real measurements. The virtual experiment also reveals the insensitivity to practical precision of sensor measurements.

  20. Problem solving in nuclear engineering using supercomputers

    International Nuclear Information System (INIS)

    Schmidt, F.; Scheuermann, W.; Schatz, A.

    1987-01-01

    The availability of supercomputers enables the engineer to formulate new strategies for problem solving. One such strategy is the Integrated Planning and Simulation System (IPSS). With the integrated systems, simulation models with greater consistency and good agreement with actual plant data can be effectively realized. In the present work some of the basic ideas of IPSS are described as well as some of the conditions necessary to build such systems. Hardware and software characteristics as realized are outlined. (orig.) [de

  1. Chemical physics of decomposition of energetic materials. Problems and prospects

    International Nuclear Information System (INIS)

    Smirnov, Lev P

    2004-01-01

    The review is concerned with analysis of the results obtained in the kinetic and mechanistic studies on decomposition of energetic materials (explosives, powders and solid propellants). It is shown that the state-of-the art in this field is inadequate to the potential of modern chemical kinetics and chemical physics. Unsolved problems are outlined and ways of their solution are proposed.

  2. Application of Plagiarism Screening Software in the Chemical Engineering Curriculum

    Science.gov (United States)

    Cooper, Matthew E.; Bullard, Lisa G.

    2014-01-01

    Plagiarism is an area of increasing concern for written ChE assignments, such as laboratory and design reports, due to ease of access to text and other materials via the internet. This study examines the application of plagiarism screening software to four courses in a university chemical engineering curriculum. The effectiveness of plagiarism…

  3. Teaching Technical Writing in a Lab Course in Chemical Engineering

    Science.gov (United States)

    Lombardo, Stephen J.

    2010-01-01

    Techniques are presented for improving the technical writing of chemical engineering students enrolled in an undergraduate laboratory course. The principles of writing covered are adopted from the book, Style: Lessons in Clarity and Grace, by Joseph M. Williams: General examples of writing are taken from this book and then are recast into examples…

  4. Problem Solving Method Based on E-Learning System for Engineering Education

    Science.gov (United States)

    Khazaal, Hasan F.

    2015-01-01

    Encouraging engineering students to handle advanced technology with multimedia, as well as motivate them to have the skills of solving the problem, are the missions of the teacher in preparing students for a modern professional career. This research proposes a scenario of problem solving in basic electrical circuits based on an e-learning system…

  5. Metabolic engineering in chemolithoautotrophic hosts for the production of fuels and chemicals.

    Science.gov (United States)

    Nybo, S Eric; Khan, Nymul E; Woolston, Benjamin M; Curtis, Wayne R

    2015-07-01

    The ability of autotrophic organisms to fix CO2 presents an opportunity to utilize this 'greenhouse gas' as an inexpensive substrate for biochemical production. Unlike conventional heterotrophic microorganisms that consume carbohydrates and amino acids, prokaryotic chemolithoautotrophs have evolved the capacity to utilize reduced chemical compounds to fix CO2 and drive metabolic processes. The use of chemolithoautotrophic hosts as production platforms has been renewed by the prospect of metabolically engineered commodity chemicals and fuels. Efforts such as the ARPA-E electrofuels program highlight both the potential and obstacles that chemolithoautotrophic biosynthetic platforms provide. This review surveys the numerous advances that have been made in chemolithoautotrophic metabolic engineering with a focus on hydrogen oxidizing bacteria such as the model chemolithoautotrophic organism (Ralstonia), the purple photosynthetic bacteria (Rhodobacter), and anaerobic acetogens. Two alternative strategies of microbial chassis development are considered: (1) introducing or enhancing autotrophic capabilities (carbon fixation, hydrogen utilization) in model heterotrophic organisms, or (2) improving tools for pathway engineering (transformation methods, promoters, vectors etc.) in native autotrophic organisms. Unique characteristics of autotrophic growth as they relate to bioreactor design and process development are also discussed in the context of challenges and opportunities for genetic manipulation of organisms as production platforms. Copyright © 2015 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  6. Applications of chemical engineering principles to glassmaking for nuclear waste fixation

    International Nuclear Information System (INIS)

    Boersma, M.D.

    1988-01-01

    There are five important differences between radwaste vitrification and normal industrial glassmaking. The hostile (radioactive) environment requires the entire process to be operated and maintained remotely. This is largely a mechanical/architectural engineering problem because radiation has very little direct impact on process chemistry or energy. A second difference is that process plant economics are dominated by safety and reliability considerations, rather than market conditions and energy costs. Third, the product quality criteria are quite different; rather than optical clarity, mechanical strength, functional shape, and esthetic appeal, the important quality for radwaste glass is its chemical durability in final storage. Fourth, the off-gases from a radwaste vitrification process are of greater environmental concern. Equipment must be airtight or under vacuum, and highly efficient gas cleanup systems must be used. Finally, feed to a radwaste glass melter is typically at least 50% water. Liquid slurry melter feed is not unheard of in commercial glassmaking but dry batch feed is normal. Slurry water more than doubles the process energy demand in the melter and causes some very large local temperature gradients. 2 figs

  7. Problems of zirconium metal production in Czechoslovakia

    International Nuclear Information System (INIS)

    Vareka, J.; Vaclavik, E.

    1975-01-01

    The problems are summed up of the production and quality control of zirconium sponge. A survey is given of industrial applications of zirconium in form of pure metal or alloys in nuclear power production, ferrous and non-ferrous metallurgy, chemical engineering and electrical engineering. A survey is also presented of the manufacture of zirconium metal in advanced capitalist countries. (J.B.)

  8. Virtual Chemical Engineering: Guidelines for E-Learning in Engineering Education

    Directory of Open Access Journals (Sweden)

    Damian Schofield

    2010-11-01

    Full Text Available Advanced three-dimensional virtual environment technology, similar to that used by the film and computer games industry can allow educational developers to rapidly create realistic three-dimensional, virtual environments. This technology has been used to generate a range of interactive learning environments across a broad spectrum of industries.The paper will discuss the implementation of these systems and extrapolate the lessons learnt into general guidelines to be considered for the development of a range of educational learning resources. These guidelines will then be discussed in the context of the development of ViRILE (Virtual Reality Interactive Learning Environment, software which simulates the configuration and operation of a polymerisation plant. This software package has been developed for use by undergraduate chemical engineers at the University of Nottingham.

  9. Inverse problems in the design, modeling and testing of engineering systems

    Science.gov (United States)

    Alifanov, Oleg M.

    1991-01-01

    Formulations, classification, areas of application, and approaches to solving different inverse problems are considered for the design of structures, modeling, and experimental data processing. Problems in the practical implementation of theoretical-experimental methods based on solving inverse problems are analyzed in order to identify mathematical models of physical processes, aid in input data preparation for design parameter optimization, help in design parameter optimization itself, and to model experiments, large-scale tests, and real tests of engineering systems.

  10. Gendered practices of constructing an engineering identity in a problem-based learning environment

    DEFF Research Database (Denmark)

    Du, Xiangyun

    2006-01-01

    of an engineering identity with masculinity and the culturally defined engineering competencies leads to different learning experiences for male and female students. The nature of hard-core engineering subjects, based on male interests, privileges men and acts as a barrier to women. The masculine culture......This article examines the learning experiences of engineering students of both genders in a problem-based and project-organized learning environment (PBL) at a Danish university. This study relates an amalgam of theories on learning and gender to the context of engineering education. Based on data...

  11. Problems in fluid flow

    International Nuclear Information System (INIS)

    Brasch, D.J.

    1986-01-01

    Chemical and mineral engineering students require texts which give guidance to problem solving to complement their main theoretical texts. This book has a broad coverage of the fluid flow problems which these students may encounter. The fundamental concepts and the application of the behaviour of liquids and gases in unit operation are dealt with. The book is intended to give numerical practice; development of theory is undertaken only when elaboration of treatments available in theoretical texts is absolutely necessary

  12. The problem of living in a world contaminated with chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Metcalf, R.L. [Univ. of Illinois, Urbana (United States)

    1990-12-31

    The proliferation of xenobiotic chemicals in the global environment poses living problems for each of us aboard {open_quotes}spaceship earth.{close_quotes} Seven case studies are presented that illustrate the magnitude of the problem that can result from waiting to identify toxic hazards until there have been decades of {open_quotes}human guinea pig{close_quotes} exposure. 25 refs., 5 tabs.

  13. Seminar Neutronika-2012. Neutron-physical problems of nuclear-power engineering. Program and abstracts

    International Nuclear Information System (INIS)

    2012-01-01

    On October, 30 - November, 2 in State Scientific Center of the Russian Federation - Institute for Physics and Power Engineering named after A.I. Leypunsky a seminar Neutron-physical problems of nuclear power engineering - Neutronika-2012 took place. On the seminar the following problems were discussed: justification of neutron-physical characteristics of reactor facilities and innovation projects; constant support of neutron-physical calculations of nuclear power installations; numerical simulation during solving reactor physics problems; simulation of neutron-physical processes in reactor facilities by Monte Carlo method; development and verification of programs for reactor facilities neutron-physical calculations; algorithms and programs for solving nonstationary problems of neutron-physical calculation of nuclear reactors; analysis of integral and reactor experiments, experimental database; justification of nuclear and radiation safety of fuel cycle [ru

  14. Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals

    DEFF Research Database (Denmark)

    Jullesson, David; David, Florian; Pfleger, Brian

    2015-01-01

    Industrial bio-processes for fine chemical production are increasingly relying on cell factories developed through metabolic engineering and synthetic biology. The use of high throughput techniques and automation for the design of cell factories, and especially platform strains, has played...... chemicals that have reached the market, key metabolic engineering tools that have allowed this to happen and some of the companies that are currently utilizing these technologies for developing industrial production processes....... an important role in the transition from laboratory research to industrial production. Model organisms such as Saccharomyces cerevisiae and Escherichia coli remain widely used host strains for industrial production due to their robust and desirable traits. This review describes some of the bio-based fine...

  15. Introduction to computational mass transfer with applications to chemical engineering

    CERN Document Server

    Yu, Kuo-Tsong

    2014-01-01

    This book presents a new computational methodology called Computational Mass Transfer (CMT). It offers an approach to rigorously simulating the mass, heat and momentum transfer under turbulent flow conditions with the help of two newly published models, namely the C’2—εC’ model and the Reynolds  mass flux model, especially with regard to predictions of concentration, temperature and velocity distributions in chemical and related processes. The book will also allow readers to understand the interfacial phenomena accompanying the mass transfer process and methods for modeling the interfacial effect, such as the influences of Marangoni convection and Rayleigh convection. The CMT methodology is demonstrated by means of its applications to typical separation and chemical reaction processes and equipment, including distillation, absorption, adsorption and chemical reactors. Professor Kuo-Tsong Yu is a Member of the Chinese Academy of Sciences. Dr. Xigang Yuan is a Professor at the School of Chemical Engine...

  16. Repurposing Mass-produced Internal Combustion Engines Quantifying the Value and Use of Low-cost Internal Combustion Piston Engines for Modular Applications in Energy and Chemical Engineering Industries

    Science.gov (United States)

    L'Heureux, Zara E.

    This thesis proposes that internal combustion piston engines can help clear the way for a transformation in the energy, chemical, and refining industries that is akin to the transition computer technology experienced with the shift from large mainframes to small personal computers and large farms of individually small, modular processing units. This thesis provides a mathematical foundation, multi-dimensional optimizations, experimental results, an engine model, and a techno-economic assessment, all working towards quantifying the value of repurposing internal combustion piston engines for new applications in modular, small-scale technologies, particularly for energy and chemical engineering systems. Many chemical engineering and power generation industries have focused on increasing individual unit sizes and centralizing production. This "bigger is better" concept makes it difficult to evolve and incorporate change. Large systems are often designed with long lifetimes, incorporate innovation slowly, and necessitate high upfront investment costs. Breaking away from this cycle is essential for promoting change, especially change happening quickly in the energy and chemical engineering industries. The ability to evolve during a system's lifetime provides a competitive advantage in a field dominated by large and often very old equipment that cannot respond to technology change. This thesis specifically highlights the value of small, mass-manufactured internal combustion piston engines retrofitted to participate in non-automotive system designs. The applications are unconventional and stem first from the observation that, when normalized by power output, internal combustion engines are one hundred times less expensive than conventional, large power plants. This cost disparity motivated a look at scaling laws to determine if scaling across both individual unit size and number of units produced would predict the two order of magnitude difference seen here. For the first

  17. Automatic differentiation tools in the dynamic simulation of chemical engineering processes

    Directory of Open Access Journals (Sweden)

    Castro M.C.

    2000-01-01

    Full Text Available Automatic Differentiation is a relatively recent technique developed for the differentiation of functions applicable directly to the source code to compute the function written in standard programming languages. That technique permits the automatization of the differentiation step, crucial for dynamic simulation and optimization of processes. The values for the derivatives obtained with AD are exact (to roundoff. The theoretical exactness of the AD comes from the fact that it uses the same rules of differentiation as in differential calculus, but these rules are applied to an algorithmic specification of the function rather than to a formula. The main purpose of this contribution is to discuss the impact of Automatic Differentiation in the field of dynamic simulation of chemical engineering processes. The influence of the differentiation technique on the behavior of the integration code, the performance of the generated code and the incorporation of AD tools in consistent initialization tools are discussed from the viewpoint of dynamic simulation of typical models in chemical engineering.

  18. Materials of 46. Scientific Assembly of Polish Chemical Society and Association of Engineers and Technicians of Chemical. Volume 1,2,3

    International Nuclear Information System (INIS)

    2003-01-01

    Scientific assemblies of Polish Chemical Society are the most important chemical meetings organised annually in Poland. Basic as well as application studies in all chemical branches have been extensively presented. The next subjects were proposed as scientific sessions and symposia topics: organic chemistry, inorganic chemistry, physical chemistry, analytical chemistry, technology and chemical engineering, polymer chemistry, solid state chemistry, catalysis, biological chemistry, chemistry and technology of coal, environmental protection, didactics of chemistry, history of chemistry, young scientist forum as well as the reports of results of works sponsored by Committee of Scientific Research

  19. ["Two professions for a single task". The introduction of chemical engineering in Spain during the first Francoism].

    Science.gov (United States)

    Toca, Angel

    2006-01-01

    Through the first half of the 20th century, chemical engineering was established as an academic option in the training of specialists for the North-American and European chemical industry, whereas it was not a special field of study in Spain until the 1990s. The reason for this delay was a battle of interests between chemist and industrial engineers to control this career during the first Francoism. This article will try to show the development and professionalization of specialists for the Spanish chemical industry.

  20. Avoid, Control, Succumb, or Balance: Engineering Students' Approaches to a Wicked Sustainability Problem

    Science.gov (United States)

    Lönngren, Johanna; Ingerman, Åke; Svanström, Magdalena

    2017-01-01

    Wicked sustainability problems (WSPs) are an important and particularly challenging type of problem. Science and engineering education can play an important role in preparing students to deal with such problems, but current educational practice may not adequately prepare students to do so. We address this gap by providing insights related to…

  1. Integration and the hold-up problem in the design organization for engineering projects

    NARCIS (Netherlands)

    Zerjav, Vedran; Hartmann, Timo; Javernick-Will, A.; Chinowsky, P.

    2012-01-01

    The paper presents a perspective of the design organization in engineering projects based on the economic concept of the hold-up problem. By integrating the economic theories on the boundaries of organizations into the existing knowledge on design in engineering projects, the paper hypothesizes a

  2. English Language Publishing in Chemical Engineering Journals from an Indian Academic's Point of View--A Broad Scientific Perspective

    Science.gov (United States)

    Palit, Sukanchan

    2016-01-01

    Scientific vision and scientific understanding in today's world are in the path of new glory. Chemical Engineering science is witnessing drastic and rapid changes. The metamorphosis of human civilization in this century is faced with vicious challenges. Progress of Chemical Engineering science, the vision of technology and the broad chemical…

  3. Abstracts of the 47. Canadian chemical engineering conference

    International Nuclear Information System (INIS)

    1997-01-01

    Chemical engineering and its role in the development of Western Canada's oil sands and heavy oil reserves was the main focus of this conference. The presentations revolved around the theme, 'The Competitive Advantage'. Features of the conference included strong participation by industry, professional development courses, and government. Energy-related sessions were entitled: (1) oil and bitumen recovery, (2) bitumen extraction and froth treatment, (3) bitumen upgrading, (4) in-situ recovery and enhanced oil recovery, (5) air quality, (6) cracking and hydrogenation, and (7) sulfur recovery and gas processing

  4. Conservation of Life as a Unifying Theme for Process Safety in Chemical Engineering Education

    Science.gov (United States)

    Klein, James A.; Davis, Richard A.

    2011-01-01

    This paper explores the use of "conservation of life" as a concept and unifying theme for increasing awareness, application, and integration of process safety in chemical engineering education. Students need to think of conservation of mass, conservation of energy, and conservation of life as equally important in engineering design and analysis.…

  5. CURRICULUM: A Chemical Engineering Course for Liberal Arts Students--Indigo: A World of Blues

    Science.gov (United States)

    Piergiovanni, Polly R.

    2012-01-01

    Sophomore liberal arts and engineering students enrolled in a course to learn and practice some basic chemical engineering side by side. The course was developed around the theme of indigo dyeing, which has an interesting history, fascinating chemistry and is accessible to all students. The students participated in a variety of active learning…

  6. Education of Sustainability Engineers

    Science.gov (United States)

    Oleschko, K.; Perrier, E.; Tarquis, A. M.

    2010-05-01

    It's not the same to educate the sustainable engineers as to prepare the engineers of Sustainability. In the latter case all existing methods of inventive creativity (Altshuller, 1988) should be introduced in the teaching and research processes in order to create a culture of innovation at a group. The Theory of Inventing Problem Solving (TRIZ) is based on the pioneer works of Genrich Altshuller (1988) and his associated. Altshuller reviewed over 2 million patents beginning in 1946 (Orlov, 2006) and developed the Laws of Evolution of Technological Systems; An Algorithm for Inventive Problem Solving (ARIZ); forty typical Techniques for Overcoming System Conflicts (TOSC); a system of 76 Standard Approaches to Inventive Problems (Standards) etc. (Fey and Rivin, 1997). Nowadays, "a theory and constructive instrument package for the controlled synthesis of ideas and the focused transformation of the object to be improved" (Orlov, 2006) are used with high efficacy as the teaching and thinking inventive problem-solving methods in some high schools (Barak and Mesika, 2006; Sokoi et al., 2008) as well as a framework for research (Moehrle, 2005) in construction industry (Zhang et al., 2009); chemical engineering (Cortes Robles et al., 2008) etc. In 2005 US Congress passed the innovation act with the intent of increasing research investment (Gupta, 2007), while China had included inventive principles of TRIZ in strategy and decision making structure design (Kai Yang, 2010). The integrating of TRIZ into eco-innovation diminishes the common conflicts between technology and environment (Chang and Chen, 2004). In our presentation we show discuss some examples of future patents elaborated by the master degree students of Queretaro University, Faculty of Engineering, Mexico using TRIZ methods. References 1. Altshuller, G., 1988. Creativity as an Exact Science. Gordon and Breach, New York. 2. Chang, Hsiang-Tang and Chen, Jahau Lewis, 2004. The conflict-problem-solving CAD software

  7. Teaching Population Balances for Chemical Engineering Students: Application to Granulation Processes

    Science.gov (United States)

    Bucala, Veronica; Pina, Juliana

    2007-01-01

    The population balance equation (PBE) is a useful tool to predict particle size distributions in granulation processes. When PBE is taught to advanced chemical engineering students, the internal coordinates (particle properties) are particularly hard to understand. In this paper, the flow of particles along different coordinates is carefully…

  8. Mass spectral chemical fingerprints reveal the molecular dependence of exhaust particulate matters on engine speeds.

    Science.gov (United States)

    Li, Yi; Zhang, Hua; Zhao, Zongshan; Tian, Yong; Liu, Kun; Jie, Feifan; Zhu, Liang; Chen, Huanwen

    2018-05-01

    Particulate matters (PMs) emitted by automobile exhaust contribute to a significant fraction of the global PMs. Extractive atmospheric pressure chemical ionization mass spectrometry (EAPCI-MS) was developed to explore the molecular dependence of PMs collected from exhaust gases produced at different vehicle engine speeds. The mass spectral fingerprints of the organic compounds embedded in differentially sized PMs (e.g., 0.22-0.45, 0.45-1.00, 1.00-2.00, 2.00-3.00, 3.00-5.00, and 5.00-10.00μm) generated at different engine speeds (e.g., 1000, 1500, 2000, 2500, and 3000r/min) were chemically profiled in the mass range of mass to charge ratio (m/z) 50-800. Organic compounds, including alcohols, aldehydes, and esters, were detected in all the PMs tested, with varied concentration levels for each individual PM sample. At relatively low engine speeds (≤1500r/min), the total amount of organic species embedded in PMs of 0.22-1.00μm was greater than in PMs of other sizes, while more organic species were found in PMs of 5.00-10.00μm at high engine speeds (≥3000r/min), indicating that the organic compounds distributed in different sizes of PMs strongly correlated with the engine speed. The experimental data showed that the EAPCI-MS technique enables molecular characterization of PMs in exhaust, revealing the chemical dependence of PMs on the engine speeds (i.e., the combustion conditions) of automobiles. Copyright © 2017. Published by Elsevier B.V.

  9. Corrosion problems of materials for mechanical, power and chemical engineering

    International Nuclear Information System (INIS)

    Bouska, P.; Cihal, V.; Malik, K.; Vyklicky, M.; Stefec, R.

    1988-01-01

    The proceedings contain 47 contributions, out of which 8 have been inputted in INIS. These are concerned with various corrosion problems of WWER primary circuit components and their testing. The factors affecting the corrosion resistance are analyzed, the simultaneous corrosion action of decontamination of steels is assessed, and the corrosion cracking of special steels is dealt with. The effects of deformation on the corrosion characteristics are examined for steel to be used in fast reactors. The corrosion potentials were measured for various steels. A testing facility for corrosion-mechanical tests is briefly described. (M.D.). 5 figs., 5 tabs., 25 refs

  10. Impact of synthetic biology and metabolic engineering on industrial production of fine chemicals.

    Science.gov (United States)

    Jullesson, David; David, Florian; Pfleger, Brian; Nielsen, Jens

    2015-11-15

    Industrial bio-processes for fine chemical production are increasingly relying on cell factories developed through metabolic engineering and synthetic biology. The use of high throughput techniques and automation for the design of cell factories, and especially platform strains, has played an important role in the transition from laboratory research to industrial production. Model organisms such as Saccharomyces cerevisiae and Escherichia coli remain widely used host strains for industrial production due to their robust and desirable traits. This review describes some of the bio-based fine chemicals that have reached the market, key metabolic engineering tools that have allowed this to happen and some of the companies that are currently utilizing these technologies for developing industrial production processes. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Surface engineering of one-dimensional tin oxide nanostructures for chemical sensors

    International Nuclear Information System (INIS)

    Ma, Yuanyuan; Qu, Yongquan; Zhou, Wei

    2013-01-01

    Nanostructured materials are promising candidates for chemical sensors due to their fascinating physicochemical properties. Among various candidates, tin oxide (SnO 2 ) has been widely explored in gas sensing elements due to its excellent chemical stability, low cost, ease of fabrication and remarkable reproducibility. We are presenting an overview on recent investigations on 1-dimensional (1D) SnO 2 nanostructures for chemical sensing. In particular, we focus on the performance of devices based on surface engineered SnO 2 nanostructures, and on aspects of morphology, size, and functionality. The synthesis and sensing mechanism of highly selective, sensitive and stable 1D nanostructures for use in chemical sensing are discussed first. This is followed by a discussion of the relationship between the surface properties of the SnO 2 layer and the sensor performance from a thermodynamic point of view. Then, the opportunities and recent progress of chemical sensors fabricated from 1D SnO 2 heterogeneous nanostructures are discussed. Finally, we summarize current challenges in terms of improving the performance of chemical (gas) sensors using such nanostructures and suggest potential applications. (author)

  12. Solving computationally expensive engineering problems

    CERN Document Server

    Leifsson, Leifur; Yang, Xin-She

    2014-01-01

    Computational complexity is a serious bottleneck for the design process in virtually any engineering area. While migration from prototyping and experimental-based design validation to verification using computer simulation models is inevitable and has a number of advantages, high computational costs of accurate, high-fidelity simulations can be a major issue that slows down the development of computer-aided design methodologies, particularly those exploiting automated design improvement procedures, e.g., numerical optimization. The continuous increase of available computational resources does not always translate into shortening of the design cycle because of the growing demand for higher accuracy and necessity to simulate larger and more complex systems. Accurate simulation of a single design of a given system may be as long as several hours, days or even weeks, which often makes design automation using conventional methods impractical or even prohibitive. Additional problems include numerical noise often pr...

  13. Incorporating Computer-Aided Software in the Undergraduate Chemical Engineering Core Courses

    Science.gov (United States)

    Alnaizy, Raafat; Abdel-Jabbar, Nabil; Ibrahim, Taleb H.; Husseini, Ghaleb A.

    2014-01-01

    Introductions of computer-aided software and simulators are implemented during the sophomore-year of the chemical engineering (ChE) curriculum at the American University of Sharjah (AUS). Our faculty concurs that software integration within the curriculum is beneficial to our students, as evidenced by the positive feedback received from industry…

  14. Design and Analysis of Questionnaires for Survey Skills in Chemical Engineering

    Science.gov (United States)

    Lucas Yagüe, Susana; Coca Sanz, Mónica; González Benito, Gerardo; Cartón López, Ángel; Urueña Alonso, Miguel Ángel; García Cubero, Mª Teresa

    2011-01-01

    The new reorganization of university education has involved relevant changes in teaching and learning methodologies in order to help students to learn more effectively and to develop important skills and competences demanded by the professional world. In this sense the new configuration of the degree in Chemical Engineering required the…

  15. Strategies and applications for incorporating physical and chemical signal gradients in tissue engineering.

    Science.gov (United States)

    Singh, Milind; Berkland, Cory; Detamore, Michael S

    2008-12-01

    From embryonic development to wound repair, concentration gradients of bioactive signaling molecules guide tissue formation and regeneration. Moreover, gradients in cellular and extracellular architecture as well as in mechanical properties are readily apparent in native tissues. Perhaps tissue engineers can take a cue from nature in attempting to regenerate tissues by incorporating gradients into engineering design strategies. Indeed, gradient-based approaches are an emerging trend in tissue engineering, standing in contrast to traditional approaches of homogeneous delivery of cells and/or growth factors using isotropic scaffolds. Gradients in tissue engineering lie at the intersection of three major paradigms in the field-biomimetic, interfacial, and functional tissue engineering-by combining physical (via biomaterial design) and chemical (with growth/differentiation factors and cell adhesion molecules) signal delivery to achieve a continuous transition in both structure and function. This review consolidates several key methodologies to generate gradients, some of which have never been employed in a tissue engineering application, and discusses strategies for incorporating these methods into tissue engineering and implant design. A key finding of this review was that two-dimensional physicochemical gradient substrates, which serve as excellent high-throughput screening tools for optimizing desired biomaterial properties, can be enhanced in the future by transitioning from two dimensions to three dimensions, which would enable studies of cell-protein-biomaterial interactions in a more native tissue-like environment. In addition, biomimetic tissue regeneration via combined delivery of graded physical and chemical signals appears to be a promising strategy for the regeneration of heterogeneous tissues and tissue interfaces. In the future, in vivo applications will shed more light on the performance of gradient-based mechanical integrity and signal delivery

  16. Identification and Analysis of Student Conceptions Used To Solve Chemical Equilibrium Problems.

    Science.gov (United States)

    Voska, Kirk W.; Heikkinen, Henry W.

    2000-01-01

    Identifies and quantifies the chemistry conceptions used by students when solving chemical equilibrium problems requiring application of LeChatelier's Principle, and explores the feasibility of designing a paper and pencil test to accomplish these purposes. Eleven prevalent incorrect student conceptions about chemical equilibrium were identified…

  17. Metabolic Engineering for Production of Biorenewable Fuels and Chemicals: Contributions of Synthetic Biology

    OpenAIRE

    Jarboe, Laura R.; Zhang, Xueli; Wang, Xuan; Moore, Jonathan C.; Shanmugam, K. T.; Ingram, Lonnie O.

    2010-01-01

    Production of fuels and chemicals through microbial fermentation of plant material is a desirable alternative to petrochemical-based production. Fermentative production of biorenewable fuels and chemicals requires the engineering of biocatalysts that can quickly and efficiently convert sugars to target products at a cost that is competitive with existing petrochemical-based processes. It is also important that biocatalysts be robust to extreme fermentation conditions, biomass-derived inhibito...

  18. Collaborative Systems Thinking: A Response to the Problems Faced by Systems Engineering's 'Middle Tier'

    Science.gov (United States)

    Phfarr, Barbara B.; So, Maria M.; Lamb, Caroline Twomey; Rhodes, Donna H.

    2009-01-01

    Experienced systems engineers are adept at more than implementing systems engineering processes: they utilize systems thinking to solve complex engineering problems. Within the space industry demographics and economic pressures are reducing the number of experienced systems engineers that will be available in the future. Collaborative systems thinking within systems engineering teams is proposed as a way to integrate systems engineers of various experience levels to handle complex systems engineering challenges. This paper uses the GOES-R Program Systems Engineering team to illustrate the enablers and barriers to team level systems thinking and to identify ways in which performance could be improved. Ways NASA could expand its engineering training to promote team-level systems thinking are proposed.

  19. Applied chemistry and environmental engineering for engineers. Manual for students and practicians. 2. ed.; Angewandte Chemie und Umwelttechnik fuer Ingenieure. Handbuch fuer Studium und betriebliche Praxis

    Energy Technology Data Exchange (ETDEWEB)

    Fessmann, J.; Orth, H.

    2002-07-01

    This is a practically oriented textbook for chemistry and environmental protection training of students of mechanical engineering, vehicle engineering, electrical engineering, space HVAc engineering etc. Students are also given useful information on the practical applications of chemistry and on environmental protection in industrial practice. The book also contains problem solutions for managing engineers in organizations of the metal and electrical branch who are confronted with chemical problems in chemical engineering, quality assurance, industrial safety and environmental protection. [German] Das Handbuch vermittelt in konzentrierter Form die Grundlagen der Chemie und Umwelttechnik und schlaegt rasch die Bruecke zur industriellen Anwendung bevorzugt in der Metall- und Elektroindustrie. Das Handbuch ist ein praxisorientiertes Lehrbuch fuer die Chemie- und Umweltschutzausbildung von Ingenieurstudenten der Fachrichtungen Maschinenbau, Fahrzeugtechnik, Elektrotechnik, Versorgungstechnik u.a. Darueberhinaus finden Schueler von Chemieleistungskursen an Gymnasien oder Chemiestudenten an Fachhochschulen oder Universitaeten viele nuetzliche Informationen ueber die Anwendungen von Chemie und Umweltschutz in der industriellen Praxis. Nicht zuletzt enthaelt das Buch Problemloesungen fuer Betriebsingenieure, insbesondere aus dem Bereich der Metall- und Elektrobranche, die mit chemischen Fragestellungen in der Verfahrenstechnik, Qualitaetssicherung oder Arbeits-/Umweltschutzueberwachung konfrontiert sind. (orig.)

  20. Chemical interaction of tetravalent actinides simulators and the engineering barrier

    International Nuclear Information System (INIS)

    Chain, Pablo; Alba, Maria D.; Castro, Miguel A.; Pavon, Esperanza; Mar Orta, M.

    2010-01-01

    Document available in extended abstract form only. The Deep Geological Repository (DGR) is the most internationally accepted option for the storage of high radioactive wastes. This confinement is based on the Multi-barrier Concept where the engineered barrier is a crucial safety wise. Nowadays, bentonite is accepted as the best argillaceous material in the engineered barrier of DGR. Additionally to its well-known physical role, a chemical interaction between lutetium, as actinide simulator, and the smectite has been demonstrated. The existence of a reaction mechanism, which was not previously described, based on the chemical interaction between the lanthanide cations and the orthosilicate anions of the lamellar structure has been identified. This finding has aroused the interest of the scientific community because lanthanides are used as simulators of high activity radionuclide (HAR) in agreement with the guidelines established in the bibliography. It has been observed that in conditions of moderate temperature and pressure a chemical interaction exists between smectites and rare earth elements (RE) and phases of insoluble di-silicate, RE 2 Si 2 O 7 , which would immobilize RE, are generated. It is remarkable that the reaction extends to all the set of the smectites, although they do not display the same reactivity, the saponite being the most reactive. The main isotopes present in the HLW belong to the actinide elements Np, Pu, Am and Cm, in addition to uranium generated by neutron capture during the fuel combustion process. The study of the mobilization of actinide (IV) thorough the bentonite barrier is limited because of their radioactivity. However, U(IV), Np(IV), Pu(IV) and Th(IV) can be simulated by the stable isotopes of the Zr(IV) and Hf(IV), because they exhibit ionic radius and physicochemical properties very similar to those of the actinide elements. It is the main objective of this research to investigate the chemical interaction of Zr(IV) as actinide

  1. Development of Chemical Engineering Course Methods Using Action Research: Case Study

    Science.gov (United States)

    Virkki-Hatakka, Terhi; Tuunila, Ritva; Nurkka, Niina

    2013-01-01

    This paper reports on the systematic development of a teaching methodology for two chemical engineering courses. The aim was to improve the quality of teaching to achieve expected learning outcomes more effectively. The development was carried out over a period of several years based on an action research methodology with data systematically…

  2. Decision Analysis on Survey and SOil Investigation Problem in Power Engineering Consultant

    OpenAIRE

    Setyaman, Amy Maulany; Sunitiyoso, Yos

    2013-01-01

    The study aims to gather and organize information for decision making against the problems arising in Power Engineering Consultant's survey and soil investigation product due to new policy in production cost efficiency that is implemented in 2012. The study conducted using Kepner and Tragoe's analytical process that consisted of four stages analytical process such as situation analysis, problem analysis, decision making analysis and potential problem analysis. As for the decision making analy...

  3. Prevention of Preharvest Sprouting through Hormone Engineering and Germination Recovery by Chemical Biology.

    Science.gov (United States)

    Nonogaki, Mariko; Nonogaki, Hiroyuki

    2017-01-01

    Vivipary, germination of seeds on the maternal plant, is observed in nature and provides ecological advantages in certain wild species, such as mangroves. However, precocious seed germination in agricultural species, such as preharvest sprouting (PHS) in cereals, is a serious issue for food security. PHS reduces grain quality and causes economical losses to farmers. PHS can be prevented by translating the basic knowledge of hormone biology in seeds into technologies. Biosynthesis of abscisic acid (ABA), which is an essential hormone for seed dormancy, can be engineered to enhance dormancy and prevent PHS. Enhancing nine- cis -epoxycarotenoid dioxygenase (NCED), a rate-limiting enzyme of ABA biosynthesis, through a chemically induced gene expression system, has successfully been used to suppress germination of Arabidopsis seeds. The more advanced system NCED positive-feedback system, which amplifies ABA biosynthesis in a seed-specific manner without chemical induction, has also been developed. The proofs of concept established in the model species are now ready to be applied to crops. A potential problem is recovery of germination from hyperdormant crop grains. Hyperdormancy induced by the NCED systems can be reversed by inducing counteracting genes, such as NCED RNA interference or gibberellin (GA) biosynthesis genes. Alternatively, seed sensitivity to ABA can be modified to rescue germination using the knowledge of chemical biology. ABA antagonists, which were developed recently, have great potential to recover germination from the hyperdormant seeds. Combination of the dormancy-imposing and -releasing approaches will establish a comprehensive technology for PHS prevention and germination recovery.

  4. Engineering Encounters: Identifying an Engineering Design Problem

    Science.gov (United States)

    Chizek, Lisa; VanMeeteren, Beth; McDermott, Mark; Uhlenberg, Jill

    2018-01-01

    Engineering is an intriguing way for students to connect the design process with their knowledge of science (NRC 2012). This article describes the "Engineering a Pancake Recipe" design process which was created to make the structure and properties of matter more meaningful for fifth grade students. The whole pancake recipe engineering…

  5. Engineered Barrier System Thermal-Hydraulic-Chemical Column Test Report

    International Nuclear Information System (INIS)

    W.E. Lowry

    2001-01-01

    The Engineered Barrier System (EBS) Thermal-Hydraulic-Chemical (THC) Column Tests provide data needed for model validation. The EBS Degradation, Flow, and Transport Process Modeling Report (PMR) will be based on supporting models for in-drift THC coupled processes, and the in-drift physical and chemical environment. These models describe the complex chemical interaction of EBS materials, including granular materials, with the thermal and hydrologic conditions that will be present in the repository emplacement drifts. Of particular interest are the coupled processes that result in mineral and salt dissolution/precipitation in the EBS environment. Test data are needed for thermal, hydrologic, and geochemical model validation and to support selection of introduced materials (CRWMS M and O 1999c). These column tests evaluated granular crushed tuff as potential invert ballast or backfill material, under accelerated thermal and hydrologic environments. The objectives of the THC column testing are to: (1) Characterize THC coupled processes that could affect performance of EBS components, particularly the magnitude of permeability reduction (increases or decreases), the nature of minerals produced, and chemical fractionation (i.e., concentrative separation of salts and minerals due to boiling-point elevation). (2) Generate data for validating THC predictive models that will support the EBS Degradation, Flow, and Transport PMR, Rev. 01

  6. Group invariance in engineering boundary value problems

    CERN Document Server

    Seshadri, R

    1985-01-01

    REFEREN CES . 156 9 Transforma.tion of a Boundary Value Problem to an Initial Value Problem . 157 9.0 Introduction . 157 9.1 Blasius Equation in Boundary Layer Flow . 157 9.2 Longitudinal Impact of Nonlinear Viscoplastic Rods . 163 9.3 Summary . 168 REFERENCES . . . . . . . . . . . . . . . . . . 168 . 10 From Nonlinear to Linear Differential Equa.tions Using Transformation Groups. . . . . . . . . . . . . . 169 . 10.1 From Nonlinear to Linear Differential Equations . 170 10.2 Application to Ordinary Differential Equations -Bernoulli's Equation . . . . . . . . . . . 173 10.3 Application to Partial Differential Equations -A Nonlinear Chemical Exchange Process . 178 10.4 Limitations of the Inspectional Group Method . 187 10.5 Summary . 188 REFERENCES . . . . 188 11 Miscellaneous Topics . 190 11.1 Reduction of Differential Equations to Algebraic Equations 190 11.2 Reduction of Order of an Ordinary Differential Equation . 191 11.3 Transformat.ion From Ordinary to Partial Differential Equations-Search for First Inte...

  7. Avoid, Control, Succumb, or Balance: Engineering Students' Approaches to a Wicked Sustainability Problem

    Science.gov (United States)

    Lönngren, Johanna; Ingerman, Åke; Svanström, Magdalena

    2017-08-01

    Wicked sustainability problems (WSPs) are an important and particularly challenging type of problem. Science and engineering education can play an important role in preparing students to deal with such problems, but current educational practice may not adequately prepare students to do so. We address this gap by providing insights related to students' abilities to address WSPs. Specifically, we aim to (I) describe key constituents of engineering students' approaches to a WSP, (II) evaluate these approaches in relation to the normative context of education for sustainable development (ESD), and (III) identify relevant aspects of learning related to WSPs. Aim I is addressed through a phenomenographic study, while aims II and III are addressed by relating the results to research literature about human problem solving, sustainable development, and ESD. We describe four qualitatively different ways of approaching a specific WSP, as the outcome of the phenomenographic study: A. Simplify and avoid, B. Divide and control, C. Isolate and succumb, and D. Integrate and balance. We identify approach D as the most appropriate approach in the context of ESD, while A and C are not. On this basis, we identify three learning objectives related to students' abilities to address WSPs: learn to use a fully integrative approach, distinguish WSPs from tame and well-structured problems, and understand and consider the normative context of SD. Finally, we provide recommendations for how these learning objectives can be used to guide the design of science and engineering educational activities.

  8. Self-Reflection and Professional Competences in the Master Program for Chemical Engineers

    NARCIS (Netherlands)

    Reijenga, J.C.; Vinken, E.; Gupta-Bhowon, M.; Jhaumeer-Laulloo, S.; Li Kam Wah, H.; Ramasami, P.

    2009-01-01

    This paper presents an investigation into the quality of self-reflection during industrial intern-ships by Chemical Engineering students at the Eindhoven University of Technology in The Netherlands. The quality of the self-reflection reports written at the end of a compulsory in-dustrial internship

  9. Compilation of contract research for the Chemical Engineering Branch, Division of Engineering Technology. Annual report for FY 1985

    International Nuclear Information System (INIS)

    1986-07-01

    This compilation of annual research reports by the contractors to the Chemical Engineering Branch, DET, is published to disseminate information from ongoing programs and covers research conducted during fiscal year 1985. The programs covered in this document include research on: (1) engineered safety feature (ESF) system effectiveness in terms of fission product retention under severe accident conditions; (2) effectiveness and safety aspects of selected decontamination methods; (3) decontamination impacts on solidification and waste disposal; (4) evaluation of nuclear facility decommissioning projects and concepts, and (5) operational schemes to prevent or mitigate the effects of hydrogen combustion during LWR accidents

  10. Chemical respiratory allergy: Reverse engineering an adverse outcome pathway

    International Nuclear Information System (INIS)

    Kimber, Ian; Dearman, Rebecca J.; Basketter, David A.; Boverhof, Darrell R.

    2014-01-01

    Allergic sensitisation of the respiratory tract by chemicals is associated with rhinitis and asthma and remains an important occupational health issue. Although less than 80 chemicals have been confirmed as respiratory allergens the adverse health effects can be serious, and in rare instances can be fatal, and there are, in addition, related socioeconomic issues. The challenges that chemical respiratory allergy pose for toxicologists are substantial. No validated methods are available for hazard identification and characterisation, and this is due in large part to the fact that there remains considerable uncertainty and debate about the mechanisms through which sensitisation of the respiratory tract is acquired. Despite that uncertainty, there is a need to establish some common understanding of the key events and processes that are involved in respiratory sensitisation to chemicals and that might in turn provide the foundations for novel approaches to safety assessment. In recent years the concept of adverse outcome pathways (AOP) has gained some considerable interest among the toxicology community as a basis for outlining the key steps leading to an adverse health outcome, while also providing a framework for focusing future research, and for developing alternative paradigms for hazard characterisation. Here we explore application of the same general principles to an examination of the induction by chemicals of respiratory sensitisation. In this instance, however, we have chosen to adopt a reverse engineering approach and to model a possible AOP for chemical respiratory allergy working backwards from the elicitation of adverse health effects to the cellular and molecular mechanisms that are implicated in the acquisition of sensitisation

  11. An Alternative Educational Approach for an Inorganic Chemistry Laboratory Course in Industrial and Chemical Engineering

    Science.gov (United States)

    Garces, Andres; Sanchez-Barba, Luis Fernando

    2011-01-01

    We describe an alternative educational approach for an inorganic chemistry laboratory module named "Experimentation in Chemistry", which is included in Industrial Engineering and Chemical Engineering courses. The main aims of the new approach were to reduce the high levels of failure and dropout on the module and to make the content match the…

  12. Process engineering applied to receiving waters

    DEFF Research Database (Denmark)

    Harremoës, Poul

    1973-01-01

    Processes in the media, which recieve waste, must be included in the sphere of interest within industry's environmental consciousness. Pollution problems are not very simple and should thus not be dealt with in too simple a fashion. Chemical engineers are very well suited to deal...

  13. Analyzing the Function of Cartilage Replacements: A Laboratory Activity to Teach High School Students Chemical and Tissue Engineering Concepts

    Science.gov (United States)

    Renner, Julie N.; Emady, Heather N.; Galas, Richards J., Jr.; Zhange, Rong; Baertsch, Chelsey D.; Liu, Julie C.

    2013-01-01

    A cartilage tissue engineering laboratory activity was developed as part of the Exciting Discoveries for Girls in Engineering (EDGE) Summer Camp sponsored by the Women In Engineering Program (WIEP) at Purdue University. Our goal was to increase awareness of chemical engineering and tissue engineering in female high school students through a…

  14. Metallurgical engineering and inspection practices in the chemical process industries

    International Nuclear Information System (INIS)

    Moller, G.E.

    1987-01-01

    The process industries, in particular the petroleum refining industry, adopted materials engineering and inspection (ME and I) practices years ago and regularly updated them because they were faced with the handling and refining of flammable, toxic, and corrosive feed stocks. These industries have a number of nonproprietary techniques and procedures, some of which may be applicable in the nuclear power generation field. Some specific inspection and engineering techniques used by the process industries within the framework of the guidelines for inspections and worthy of detailed description include the following: (1) sentry drilling or safety drilling of piping subject to relatively uniform corrosion, such as feedwater heater piping, steam piping, and extraction steam piping; (2) on-stream radiography for thickness measurement and detection of unusual conditions - damaged equipment such as valve blockage; (3) critical analysis of the chemical and refining processes for the relative probability of corrosion; (4) communication of valuable experience within the industry; (5) on-stream ultrasonic thickness testing; and (6) on-stream and off-stream crack and flaw detection. The author, trained in the petroleum refining industry but versed in electric utilities, pulp and paper, chemical process, marine, mining, water handling, waste treatment, and geothermal processes, discusses individual practices of these various industries in the paper

  15. Design of problem-specific evolutionary algorithm/mixed-integer programming hybrids: two-stage stochastic integer programming applied to chemical batch scheduling

    Science.gov (United States)

    Urselmann, Maren; Emmerich, Michael T. M.; Till, Jochen; Sand, Guido; Engell, Sebastian

    2007-07-01

    Engineering optimization often deals with large, mixed-integer search spaces with a rigid structure due to the presence of a large number of constraints. Metaheuristics, such as evolutionary algorithms (EAs), are frequently suggested as solution algorithms in such cases. In order to exploit the full potential of these algorithms, it is important to choose an adequate representation of the search space and to integrate expert-knowledge into the stochastic search operators, without adding unnecessary bias to the search. Moreover, hybridisation with mathematical programming techniques such as mixed-integer programming (MIP) based on a problem decomposition can be considered for improving algorithmic performance. In order to design problem-specific EAs it is desirable to have a set of design guidelines that specify properties of search operators and representations. Recently, a set of guidelines has been proposed that gives rise to so-called Metric-based EAs (MBEAs). Extended by the minimal moves mutation they allow for a generalization of EA with self-adaptive mutation strength in discrete search spaces. In this article, a problem-specific EA for process engineering task is designed, following the MBEA guidelines and minimal moves mutation. On the background of the application, the usefulness of the design framework is discussed, and further extensions and corrections proposed. As a case-study, a two-stage stochastic programming problem in chemical batch process scheduling is considered. The algorithm design problem can be viewed as the choice of a hierarchical decision structure, where on different layers of the decision process symmetries and similarities can be exploited for the design of minimal moves. After a discussion of the design approach and its instantiation for the case-study, the resulting problem-specific EA/MIP is compared to a straightforward application of a canonical EA/MIP and to a monolithic mathematical programming algorithm. In view of the

  16. Measuring adsorption, diffusion and flow in chemical engineering: applications of magnetic resonance to porous media

    International Nuclear Information System (INIS)

    Gladden, Lynn F; Mitchell, Jonathan

    2011-01-01

    Magnetic resonance (MR) techniques are increasingly used to improve our understanding of the multi-component, multi-phase processes encountered in chemical engineering. This review brings together many of the MR techniques used, and often developed specifically, to study chemical engineering systems and, in particular, processes occurring within porous media. Pulse sequences for relaxometry, pulsed field gradient measurements of diffusion, imaging and velocimetry measurements are described. Recent applications of these MR pulse sequences to microporous, mesoporous and macroporous structures are then reviewed. Considering the microporous and mesoporous systems, we focus attention on studies of rock cores, manufactured materials such as cement and gypsum plaster, and catalysts. When considering macroporous structures, the transport through packed beds of particles typical of fixed-bed catalytic reactors is reviewed; a brief overview of the increasing research interest in gas-solid fluidized beds is also presented. We highlight the field of sparse k-space sampling as an area that is in its infancy and suggest that, combined with Bayesian methods, it will offer new opportunities in both extending the application of high-field MR techniques to chemical engineering and increasing the range of measurements that can be carried out using low-field hardware.

  17. Proceedings of chemical engineering in nuclear technology - national seminar on recent advances in fuel cycle technologies: book of abstracts

    International Nuclear Information System (INIS)

    2014-01-01

    Kalpakkam Regional Centre of Indian Institute of Chemical Engineers is embarking on conducting a series of national seminars on Chemical Engineering in Nuclear Technology 2014. For CHEMENT-2014 the theme was Seminar on recent advances in fuel cycle technologies. The topics covered included research and development, modeling and simulation and equipment development. Papers relevant to INIS are indexed separately

  18. Engineering Courses on Computational Thinking Through Solving Problems in Artificial Intelligence

    Directory of Open Access Journals (Sweden)

    Piyanuch Silapachote

    2017-09-01

    Full Text Available Computational thinking sits at the core of every engineering and computing related discipline. It has increasingly emerged as its own subject in all levels of education. It is a powerful cornerstone for cognitive development, creative problem solving, algorithmic thinking and designs, and programming. How to effectively teach computational thinking skills poses real challenges and creates opportunities. Targeting entering computer science and engineering undergraduates, we resourcefully integrate elements from artificial intelligence (AI into introductory computing courses. In addition to comprehension of the essence of computational thinking, practical exercises in AI enable inspirations of collaborative problem solving beyond abstraction, logical reasoning, critical and analytical thinking. Problems in machine intelligence systems intrinsically connect students to algorithmic oriented computing and essential mathematical foundations. Beyond knowledge representation, AI fosters a gentle introduction to data structures and algorithms. Focused on engaging mental tool, a computer is never a necessity. Neither coding nor programming is ever required. Instead, students enjoy constructivist classrooms designed to always be active, flexible, and highly dynamic. Learning to learn and reflecting on cognitive experiences, they rigorously construct knowledge from collectively solving exciting puzzles, competing in strategic games, and participating in intellectual discussions.

  19. Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering.

    Science.gov (United States)

    Nuñez, James K; Harrington, Lucas B; Doudna, Jennifer A

    2016-03-18

    The application of the CRISPR-Cas9 system for genome engineering has revolutionized the ability to interrogate genomes of mammalian cells. Programming the Cas9 endonuclease to induce DNA breaks at specified sites is achieved by simply modifying the sequence of its cognate guide RNA. Although Cas9-mediated genome editing has been shown to be highly specific, cleavage events at off-target sites have also been reported. Minimizing, and eventually abolishing, unwanted off-target cleavage remains a major goal of the CRISPR-Cas9 technology before its implementation for therapeutic use. Recent efforts have turned to chemical biology and biophysical approaches to engineer inducible genome editing systems for controlling Cas9 activity at the transcriptional and protein levels. Here, we review recent advancements to modulate Cas9-mediated genome editing by engineering split-Cas9 constructs, inteins, small molecules, protein-based dimerizing domains, and light-inducible systems.

  20. On-line services offered by 'Fachinformationszentrum Chemie' to the chemical engineer

    International Nuclear Information System (INIS)

    Krietsch, W.

    1979-01-01

    An introduction to some basic concepts of computerized literature searches is followed by an account of the data stores at 'Fachinformationszentrum Chemie', insofar as they are of interest to chemical engineers. An example of a dialogue search is presented. Some data banks of affiliated organizations and other information centres are then presented. In conclusion current developments and especially EURONET are considered. (orig.) [de

  1. Covalent and non-covalent chemical engineering of actin for biotechnological applications.

    Science.gov (United States)

    Kumar, Saroj; Mansson, Alf

    2017-11-15

    The cytoskeletal filaments are self-assembled protein polymers with 8-25nm diameters and up to several tens of micrometres length. They have a range of pivotal roles in eukaryotic cells, including transportation of intracellular cargoes (primarily microtubules with dynein and kinesin motors) and cell motility (primarily actin and myosin) where muscle contraction is one example. For two decades, the cytoskeletal filaments and their associated motor systems have been explored for nanotechnological applications including miniaturized sensor systems and lab-on-a-chip devices. Several developments have also revolved around possible exploitation of the filaments alone without their motor partners. Efforts to use the cytoskeletal filaments for applications often require chemical or genetic engineering of the filaments such as specific conjugation with fluorophores, antibodies, oligonucleotides or various macromolecular complexes e.g. nanoparticles. Similar conjugation methods are also instrumental for a range of fundamental biophysical studies. Here we review methods for non-covalent and covalent chemical modifications of actin filaments with focus on critical advantages and challenges of different methods as well as critical steps in the conjugation procedures. We also review potential uses of the engineered actin filaments in nanotechnological applications and in some key fundamental studies of actin and myosin function. Finally, we consider possible future lines of investigation that may be addressed by applying chemical conjugation of actin in new ways. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  2. Engineering-Based Problem Solving in the Middle School: Design and Construction with Simple Machines

    Science.gov (United States)

    English, Lyn D.; Hudson, Peter; Dawes, Les

    2013-01-01

    Incorporating engineering concepts into middle school curriculum is seen as an effective way to improve students' problem-solving skills. A selection of findings is reported from a science, technology, engineering and mathematics (STEM)-based unit in which students in the second year (grade 8) of a three-year longitudinal study explored…

  3. Air pollution engineering

    Science.gov (United States)

    Maduna, Karolina; Tomašić, Vesna

    2017-11-01

    Air pollution is an environmental and a social problem which leads to a multitude of adverse effects on human health and standard of human life, state of the ecosystems and global change of climate. Air pollutants are emitted from natural, but mostly from anthropogenic sources and may be transported over long distances. Some air pollutants are extremely stable in the atmosphere and may accumulate in the environment and in the food chain, affecting human beings, animals and natural biodiversity. Obviously, air pollution is a complex problem that poses multiple challenges in terms of management and abatements of the pollutants emission. Effective approach to the problems of air pollution requires a good understanding of the sources that cause it, knowledge of air quality status and future trends as well as its impact on humans and ecosystems. This chapter deals with the complexities of the air pollution and presents an overview of different technical processes and equipment for air pollution control, as well as basic principles of their work. The problems of air protection as well as protection of other ecosystems can be solved only by the coordinated endeavors of various scientific and engineering disciplines, such as chemistry, physics, biology, medicine, chemical engineering and social sciences. The most important engineering contribution is mostly focused on development, design and operation of equipment for the abatement of harmful emissions into environment.

  4. Energy production systems engineering

    CERN Document Server

    Blair, Thomas Howard

    2017-01-01

    Energy Production Systems Engineering presents IEEE, Electrical Apparatus Service Association (EASA), and International Electrotechnical Commission (IEC) standards of engineering systems and equipment in utility electric generation stations. Electrical engineers that practice in the energy industry must understand the specific characteristics of electrical and mechanical equipment commonly applied to energy production and conversion processes, including the mechanical and chemical processes involved, in order to design, operate and maintain electrical systems that support and enable these processes. To aid this understanding, Energy Production Systems Engineeringdescribes the equipment and systems found in various types of utility electric generation stations. This information is accompanied by examples and practice problems. It also addresses common issues of electrical safety that arise in electric generation stations.

  5. Chemical Reactive Anchoring Lipids with Different Performance for Cell Surface Re-engineering Application.

    Science.gov (United States)

    Vabbilisetty, Pratima; Boron, Mallorie; Nie, Huan; Ozhegov, Evgeny; Sun, Xue-Long

    2018-02-28

    Introduction of selectively chemical reactive groups at the cell surface enables site-specific cell surface labeling and modification opportunity, thus facilitating the capability to study the cell surface molecular structure and function and the molecular mechanism it underlies. Further, it offers the opportunity to change or improve a cell's functionality for interest of choice. In this study, two chemical reactive anchor lipids, phosphatidylethanolamine-poly(ethylene glycol)-dibenzocyclooctyne (DSPE-PEG 2000 -DBCO) and cholesterol-PEG-dibenzocyclooctyne (CHOL-PEG 2000 -DBCO) were synthesized and their potential application for cell surface re-engineering via lipid fusion were assessed with RAW 264.7 cells as a model cell. Briefly, RAW 264.7 cells were incubated with anchor lipids under various concentrations and at different incubation times. The successful incorporation of the chemical reactive anchor lipids was confirmed by biotinylation via copper-free click chemistry, followed by streptavidin-fluorescein isothiocyanate binding. In comparison, the cholesterol-based anchor lipid afforded a higher cell membrane incorporation efficiency with less internalization than the phospholipid-based anchor lipid. Low cytotoxicity of both anchor lipids upon incorporation into the RAW 264.7 cells was observed. Further, the cell membrane residence time of the cholesterol-based anchor lipid was evaluated with confocal microscopy. This study suggests the potential cell surface re-engineering applications of the chemical reactive anchor lipids.

  6. Chemical Reactive Anchoring Lipids with Different Performance for Cell Surface Re-engineering Application

    Science.gov (United States)

    2018-01-01

    Introduction of selectively chemical reactive groups at the cell surface enables site-specific cell surface labeling and modification opportunity, thus facilitating the capability to study the cell surface molecular structure and function and the molecular mechanism it underlies. Further, it offers the opportunity to change or improve a cell’s functionality for interest of choice. In this study, two chemical reactive anchor lipids, phosphatidylethanolamine–poly(ethylene glycol)–dibenzocyclooctyne (DSPE–PEG2000–DBCO) and cholesterol–PEG–dibenzocyclooctyne (CHOL–PEG2000–DBCO) were synthesized and their potential application for cell surface re-engineering via lipid fusion were assessed with RAW 264.7 cells as a model cell. Briefly, RAW 264.7 cells were incubated with anchor lipids under various concentrations and at different incubation times. The successful incorporation of the chemical reactive anchor lipids was confirmed by biotinylation via copper-free click chemistry, followed by streptavidin-fluorescein isothiocyanate binding. In comparison, the cholesterol-based anchor lipid afforded a higher cell membrane incorporation efficiency with less internalization than the phospholipid-based anchor lipid. Low cytotoxicity of both anchor lipids upon incorporation into the RAW 264.7 cells was observed. Further, the cell membrane residence time of the cholesterol-based anchor lipid was evaluated with confocal microscopy. This study suggests the potential cell surface re-engineering applications of the chemical reactive anchor lipids. PMID:29503972

  7. APPLYING PROFESSIONALLY ORIENTED PROBLEMS OF MATHEMATICAL MODELING IN TEACHING STUDENTS OF ENGINEERING DEPARTMENTS

    Directory of Open Access Journals (Sweden)

    Natal’ya Yur’evna Gorbunova

    2017-06-01

    Full Text Available We described several aspects of organizing student research work, as well as solving a number of mathematical modeling problems: professionally-oriented, multi-stage, etc. We underlined the importance of their economic content. Samples of using such problems in teaching Mathematics at agricultural university were given. Several questions connected with information material selection and peculiarities of research problems application were described. Purpose. The author aims to show the possibility and necessity of using professionally-oriented problems of mathematical modeling in teaching Mathematics at agricultural university. The subject of analysis is including such problems into educational process. Methodology. The main research method is dialectical method of obtaining knowledge of finding approaches to selection, writing and using mathematical modeling and professionally-oriented problems in educational process; the methodology is study of these methods of obtaining knowledge. Results. As a result of analysis of literature, students opinions, observation of students work, and taking into account personal teaching experience, it is possible to make conclusion about importance of using mathematical modeling problems, as it helps to systemize theoretical knowledge, apply it to practice, raise students study motivation in engineering sphere. Practical implications. Results of the research can be of interest for teachers of Mathematics in preparing Bachelor and Master students of engineering departments of agricultural university both for theoretical research and for modernization of study courses.

  8. Certain aspects of the environmental impact of nuclear power engineering and thermal power engineering

    Energy Technology Data Exchange (ETDEWEB)

    Malenchenko, A F [AN Belorusskoj SSR, Minsk. Inst. Yadernoj Ehnergetiki

    1979-01-01

    A review is made of the both environmental impact and hazard to man resulting from nuclear power engineering as compared with those of thermal power engineering. At present, in addition to such criteria, as physical-chemical characteristic of energy sources, their efficiency and accessibility for exploitation, new requirements were substantiated in relation to safety of their utilization for environment. So, one of essential problems of nuclear power engineering development consists in assessment and prediction of radioecological consequence. The analysis and operating experience of more than 1000 reactor/years with no accidents and harm for pupulation show, that in respect to impact on environment and man nuclear power engineering is much more safe in comparison with energy sources using tradidional fossile fuel.

  9. Metabolic engineering of Escherichia coli: a sustainable industrial platform for bio-based chemical production.

    Science.gov (United States)

    Chen, Xianzhong; Zhou, Li; Tian, Kangming; Kumar, Ashwani; Singh, Suren; Prior, Bernard A; Wang, Zhengxiang

    2013-12-01

    In order to decrease carbon emissions and negative environmental impacts of various pollutants, more bulk and/or fine chemicals are produced by bioprocesses, replacing the traditional energy and fossil based intensive route. The Gram-negative rod-shaped bacterium, Escherichia coli has been studied extensively on a fundamental and applied level and has become a predominant host microorganism for industrial applications. Furthermore, metabolic engineering of E. coli for the enhanced biochemical production has been significantly promoted by the integrated use of recent developments in systems biology, synthetic biology and evolutionary engineering. In this review, we focus on recent efforts devoted to the use of genetically engineered E. coli as a sustainable platform for the production of industrially important biochemicals such as biofuels, organic acids, amino acids, sugar alcohols and biopolymers. In addition, representative secondary metabolites produced by E. coli will be systematically discussed and the successful strategies for strain improvements will be highlighted. Moreover, this review presents guidelines for future developments in the bio-based chemical production using E. coli as an industrial platform. Copyright © 2013 Elsevier Inc. All rights reserved.

  10. Chemical Disarmament: Current Problems in Implementing the Chemical Weapons Convention

    Directory of Open Access Journals (Sweden)

    Matoušek, J.

    2006-03-01

    Full Text Available The Chemical Weapons Convention (CWC is briefly characterised by stressing its main pillars, such as verified destruction ofCWstockpiles and destruction/conversion ofCWproduction facilities (CWPFs, verified non-production of CW by the chemical industries, assistance and protection, and international cooperation. The CWC´s leading principle in defining theCW(protecting it generally against scientific and technological development, i. e. so called General Purpose Criterion is thoroughly elucidated showing its relation to the CWC´s sophisticated verification system. Status of implementation (as of August 2005 shows main data obligatory declared by the States Parties (SP, among them 6 possessors of CW stockpiles (Russia, USA, India, South Korea, Albania and Libya. From the declared 71 373 agent-tons, 12 889 have been destroyed, from the declared 8 679 M items of munitions (containers, 2 420 have been destroyed, which means that the anticipated 10 years deadline for CW destruction (after entry into force – EIF will be not managed. For Russia and USA the allowed extension by another 5 years has been already agreed. From the 64 CWPFs (operational after 1946, declared by 12 SPs, 53 have been certified as destroyed/converted. The Organisation for the Prohibition of Chemical Weapons (OPCW is briefly presented and main results of the First Review Conference (2003 analysed on the base of the adopted principal documents. Future problems of implementing the CWC are connected in the first line with its universality, because among 16 non-SPs, several countries (located mainly in the Near East and on the Korean peninsula are presumed to be CW-possessors. Special emphasis is laid on both, threats and benefits of the scientific and technological development for current implementing the CWC as well as of its implementation in future after all CW stockpiles have been destroyed.

  11. EXPLORING THE PROBLEMS FACED BY TECHNICAL SCHOOL STUDENTS IN LEARNING ENGINEERING COURSES

    Directory of Open Access Journals (Sweden)

    RAMLEE MUSTAPHA

    2014-12-01

    Full Text Available The teaching of engineering courses is relatively challenging due to the nature of the courses that are perceived as “difficult courses” by a number of students. Thus, the purpose of this action research was to explore the problems faced by electrical and electronic engineering (PKEE students studying a difficult topic–transistor. This research was also aimed at identifying the students’ attitude towards Problem-based Learning (PBL. Literature has shown that PBL could enhance students’ understanding and make the learning more meaningful. The theoretical framework of this study was based on Kemmis and Mc Taggart model. Cooperative learning method was also utilised in this study consisted of Jigsaw technique in the first and second rounds of the study. In the final round, the discussion method was used. In an action research design, a classroom is a usual research site. Thus, an engineering class of 30 Form 5 students in a Technical School was selected. The PBL method was applied in the class for a nine-week duration. Empirical data were gathered from peer assessment, observation, and pre- and post-tests. The data were described descriptively using frequency, mean and standard deviation. The main results show that the students were more interactive and their post-test result shows significant increases. In terms of the attitude towards PBL, the participants rated PBL highly. The participants also assert that the main benefits of PBL include enhancing their collaborative and problem-solving skills.

  12. A Multi-Institution Study of Student Demographics and Outcomes in Chemical Engineering

    Science.gov (United States)

    Lord, Susan M.; Layton, Richard A.; Ohland, Matthew W.; Brawner, Catherine E.; Long, Russell A.

    2014-01-01

    Using a large multi-institutional dataset, we describe demographics and outcomes for students starting in and transferring into chemical engineering (ChE). In this dataset, men outnumber women in ChE except among black students. While ChE starters graduate in ChE at rates comparable to or above their racial/ethnic population average for…

  13. SIAM Conference on Computational Science and Engineering

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2005-08-29

    The Second SIAM Conference on Computational Science and Engineering was held in San Diego from February 10-12, 2003. Total conference attendance was 553. This is a 23% increase in attendance over the first conference. The focus of this conference was to draw attention to the tremendous range of major computational efforts on large problems in science and engineering, to promote the interdisciplinary culture required to meet these large-scale challenges, and to encourage the training of the next generation of computational scientists. Computational Science & Engineering (CS&E) is now widely accepted, along with theory and experiment, as a crucial third mode of scientific investigation and engineering design. Aerospace, automotive, biological, chemical, semiconductor, and other industrial sectors now rely on simulation for technical decision support. For federal agencies also, CS&E has become an essential support for decisions on resources, transportation, and defense. CS&E is, by nature, interdisciplinary. It grows out of physical applications and it depends on computer architecture, but at its heart are powerful numerical algorithms and sophisticated computer science techniques. From an applied mathematics perspective, much of CS&E has involved analysis, but the future surely includes optimization and design, especially in the presence of uncertainty. Another mathematical frontier is the assimilation of very large data sets through such techniques as adaptive multi-resolution, automated feature search, and low-dimensional parameterization. The themes of the 2003 conference included, but were not limited to: Advanced Discretization Methods; Computational Biology and Bioinformatics; Computational Chemistry and Chemical Engineering; Computational Earth and Atmospheric Sciences; Computational Electromagnetics; Computational Fluid Dynamics; Computational Medicine and Bioengineering; Computational Physics and Astrophysics; Computational Solid Mechanics and Materials; CS

  14. Engineering Ligninolytic Consortium for Bioconversion of Lignocelluloses to Ethanol and Chemicals.

    Science.gov (United States)

    Bilal, Muhammad; Nawaz, Muhammad Zohaib; Iqbal, Hafiz M N; Hou, Jialin; Mahboob, Shahid; Al-Ghanim, Khalid A; Cheng, Hairong

    2018-01-01

    Rising environmental concerns and recent global scenario of cleaner production and consumption are leading to the design of green industrial processes to produce alternative fuels and chemicals. Although bioethanol is one of the most promising and eco-friendly alternatives to fossil fuels yet its production from food and feed has received much negative criticism. The main objective of this study was to present the noteworthy potentialities of lignocellulosic biomass as an enormous and renewable biological resource. The particular focus was also given on engineering ligninolytic consortium for bioconversion of lignocelluloses to ethanol and chemicals on sustainable and environmentally basis. Herein, an effort has been made to extensively review, analyze and compile salient information related to the topic of interest. Several authentic bibliographic databases including PubMed, Scopus, Elsevier, Springer, Bentham Science and other scientific databases were searched with utmost care, and inclusion/ exclusion criterion was adopted to appraise the quality of retrieved peer-reviewed research literature. Bioethanol production from lignocellulosic biomass can largely satisfy the possible inconsistency of first-generation ethanol since it utilizes inedible lignocellulosic feedstocks, primarily sourced from agriculture and forestry wastes. Two major polysaccharides in lignocellulosic biomass namely, cellulose and hemicellulose constitute a complex lignocellulosic network by connecting with lignin, which is highly recalcitrant to depolymerization. Several attempts have been made to reduce the cost involved in the process through improving the pretreatment process. While, the ligninolytic enzymes of white rot fungi (WRF) including laccase, lignin peroxidase (LiP), and manganese peroxidase (MnP) have appeared as versatile biocatalysts for delignification of several lignocellulosic residues. The first part of the review is mainly focused on engineering ligninolytic consortium

  15. New technologies - new corrosion problems

    International Nuclear Information System (INIS)

    Heitz, E.

    1994-01-01

    Adequate resistance of materials to corrosion is equally important for classical and for new technologies. This article considers the economic consequences of corrosion damage and, in addition to the long-known GNP orientation, presents a new approach to the estimation of the costs of corrosion and corrosion protection via maintenance and especially corrosion-related maintenance. The significance of ''high-tech'', ''medium-tech'' and ''low-tech'' material and corrosion problems is assessed. Selected examples taken from new technologies in the areas of power engineering, environmental engineering, chemical engineering, and biotechnology demonstrate the great significance of the problems. It is concluded that corrosion research and corrosion prevention technology will never come to an end but will constantly face new problems. Two technologies are of particular interest since they focus attention on new methods of investigation: microelectronics and final disposal of radioactive wastes. The article closes by considering the importance of the transfer of experience and technology. Since the manufacturs and operators of machines and plant do not generally have access to the very latest knowledge, they should be kept informed through advisory services, experimental studies, databases, and further education. (orig.) [de

  16. Mechatronic Control Engineering: A Problem Oriented And Project Based Learning Curriculum In Mechatronic

    DEFF Research Database (Denmark)

    Pedersen, Henrik Clemmensen; Andersen, Torben Ole; Hansen, Michael Rygaard

    2008-01-01

    Mechatronics is a field of multidisciplinary engineering that not only requires knowledge about different technical areas, but also insight into how to combine technologies optimally, to design efficient products and systems.This paper addresses the group project based and problem-oriented learning...... the well established methods from control engineering form very powerful techniques in both analysis and synthesis of mechatronic systems. The necessary skills for mechatronic engineers are outlined followed up by a discussion on how problem oriented project based learning is implemented. A complete...... curriculum named Mechatronic Control Engineering is presented, which is started at Aalborg University, Denmark, and the content of the semesters and projects are described. The projects are all characterized by the use of simulation and control for the purpose of analyzing and designing complex commercial...

  17. Chemical and biological sensors based on defect-engineered graphene mesh field-effect transistors.

    Science.gov (United States)

    Cho, Seunghee H; Kwon, Sun Sang; Yi, Jaeseok; Park, Won Il

    2016-01-01

    Graphene has been intensively studied for applications to high-performance sensors, but the sensing characteristics of graphene devices have varied from case to case, and the sensing mechanism has not been satisfactorily determined thus far. In this review, we describe recent progress in engineering of the defects in graphene grown by a silica-assisted chemical vapor deposition technique and elucidate the effect of the defects upon the electrical response of graphene sensors. This review provides guidelines for engineering and/or passivating defects to improve sensor performance and reliability.

  18. Coagulation sensors based on magnetostrictive delay lines for biomedical and chemical engineering applications

    International Nuclear Information System (INIS)

    Maliaritsi, E.; Zoumpoulakis, L.; Simitzis, J.; Vassiliou, P.; Hristoforou, E.

    2006-01-01

    Coagulation sensors based on the magnetostrictive delay line technique are presented in this paper. They are based on magnetostrictive ribbons and are used for measuring the coagulation, curing or solidification time of different liquids. Experimental results indicate that the presented sensing elements can determine the blood coagulation with remarkable repeatability, thus allowing their use as blood coagulation sensors. Additionally, results indicate that they can also measure curing time of resins, solidification of fluids and coagulation of chemical substances, therefore allowing their implementation in chemical engineering applications

  19. Application of an engineering problem-solving methodology to address persistent problems in patient safety: a case study on retained surgical sponges after surgery.

    Science.gov (United States)

    Anderson, Devon E; Watts, Bradley V

    2013-09-01

    Despite innumerable attempts to eliminate the postoperative retention of surgical sponges, the medical error persists in operating rooms worldwide and places significant burden on patient safety, quality of care, financial resources, and hospital/physician reputation. The failure of countless solutions, from new sponge counting methods to radio labeled sponges, to truly eliminate the event in the operating room requires that the emerging field of health-care delivery science find innovative ways to approach the problem. Accordingly, the VA National Center for Patient Safety formed a unique collaboration with a team at the Thayer School of Engineering at Dartmouth College to evaluate the retention of surgical sponges after surgery and find a solution. The team used an engineering problem solving methodology to develop the best solution. To make the operating room a safe environment for patients, the team identified a need to make the sponge itself safe for use as opposed to resolving the relatively innocuous counting methods. In evaluation of this case study, the need for systematic engineering evaluation to resolve problems in health-care delivery becomes clear.

  20. Development and Application of 3D Printed Mesoreactors in Chemical Engineering Education

    Science.gov (United States)

    Tabassum, Tahseen; Iloska, Marija; Scuereb, Daniel; Taira, Noriko; Jin, Chongguang; Zaitsev, Vladimir; Afshar, Fara; Kim, Taejin

    2018-01-01

    3D printing technology has an enormous potential to apply to chemical engineering education. In this paper, we describe several designs of 3D printed mesoreactors (Y-shape, T-shape, and Long channel shape) using the following steps: reactor sketching, CAD modeling, and reactor printing. With a focus on continuous plug flow mesoreactors (PFRs, i.d.…

  1. Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals

    Science.gov (United States)

    Thess, Andreas; Grund, Stefanie; Mui, Barbara L; Hope, Michael J; Baumhof, Patrick; Fotin-Mleczek, Mariola; Schlake, Thomas

    2015-01-01

    Being a transient carrier of genetic information, mRNA could be a versatile, flexible, and safe means for protein therapies. While recent findings highlight the enormous therapeutic potential of mRNA, evidence that mRNA-based protein therapies are feasible beyond small animals such as mice is still lacking. Previous studies imply that mRNA therapeutics require chemical nucleoside modifications to obtain sufficient protein expression and avoid activation of the innate immune system. Here we show that chemically unmodified mRNA can achieve those goals as well by applying sequence-engineered molecules. Using erythropoietin (EPO) driven production of red blood cells as the biological model, engineered Epo mRNA elicited meaningful physiological responses from mice to nonhuman primates. Even in pigs of about 20 kg in weight, a single adequate dose of engineered mRNA encapsulated in lipid nanoparticles (LNPs) induced high systemic Epo levels and strong physiological effects. Our results demonstrate that sequence-engineered mRNA has the potential to revolutionize human protein therapies. PMID:26050989

  2. Role of knowledge based engineering in Heavy Water Plants and its relevance to chemical industry

    International Nuclear Information System (INIS)

    Sonde, R.R.

    2002-01-01

    The development of heavy water technology under the Department of Atomic Energy in India is carried out based on a mission oriented programme and this was backed up by a committed and highly trained manpower with a single minded pursuit to achieve the goal of making India self-sufficient in this challenging area. The paper gives step by step methodology followed in completion of the above mission which has become a benchmark in the chemical industry. A large sized chemical industry (Heavy Water plant being once such industry) has many features which are similar. The process design typically includes design of reactors, distillation columns, heat exchange networks, fluid transfer machinery, support utility systems etc. Besides, there are other issues like safety engineering, selection of materials, commissioning strategies and operating philosophies which are quite common to almost all chemical industries. Heavy water board has engineered and set up large scale heavy water plants and the technology for production of heavy water is completely assimilated in India and this paper tries to bring about some of the strategies which were instrumental in achieving this. The story of success in this technology can most certainly be followed in development of any other process technology. The important factors in the development of this technology is based on integration of R and D, process design, engineering backup, safety features, role of good construction and project management and good operating practices. One more important fact in this technology development is continuous improvement in operation and use of knowledge based engineering for debottlenecking. (author)

  3. Expanding the chemical palate of cells by combining systems biology and metabolic engineering.

    Science.gov (United States)

    Curran, Kathleen A; Alper, Hal S

    2012-07-01

    The field of Metabolic Engineering has recently undergone a transformation that has led to a rapid expansion of the chemical palate of cells. Now, it is conceivable to produce nearly any organic molecule of interest using a cellular host. Significant advances have been made in the production of biofuels, biopolymers and precursors, pharmaceuticals and nutraceuticals, and commodity and specialty chemicals. Much of this rapid expansion in the field has been, in part, due to synergies and advances in the area of systems biology. Specifically, the availability of functional genomics, metabolomics and transcriptomics data has resulted in the potential to produce a wealth of new products, both natural and non-natural, in cellular factories. The sheer amount and diversity of this data however, means that uncovering and unlocking novel chemistries and insights is a non-obvious exercise. To address this issue, a number of computational tools and experimental approaches have been developed to help expedite the design process to create new cellular factories. This review will highlight many of the systems biology enabling technologies that have reduced the design cycle for engineered hosts, highlight major advances in the expanded diversity of products that can be synthesized, and conclude with future prospects in the field of metabolic engineering. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. Testing Foreign Language Impact on Engineering Students' Scientific Problem-Solving Performance

    Science.gov (United States)

    Tatzl, Dietmar; Messnarz, Bernd

    2013-01-01

    This article investigates the influence of English as the examination language on the solution of physics and science problems by non-native speakers in tertiary engineering education. For that purpose, a statistically significant total number of 96 students in four year groups from freshman to senior level participated in a testing experiment in…

  5. Mathematical modeling and computational intelligence in engineering applications

    CERN Document Server

    Silva Neto, Antônio José da; Silva, Geraldo Nunes

    2016-01-01

    This book brings together a rich selection of studies in mathematical modeling and computational intelligence, with application in several fields of engineering, like automation, biomedical, chemical, civil, electrical, electronic, geophysical and mechanical engineering, on a multidisciplinary approach. Authors from five countries and 16 different research centers contribute with their expertise in both the fundamentals and real problems applications based upon their strong background on modeling and computational intelligence. The reader will find a wide variety of applications, mathematical and computational tools and original results, all presented with rigorous mathematical procedures. This work is intended for use in graduate courses of engineering, applied mathematics and applied computation where tools as mathematical and computational modeling, numerical methods and computational intelligence are applied to the solution of real problems.

  6. Case study of a problem-based learning course of physics in a telecommunications engineering degree

    Science.gov (United States)

    Macho-Stadler, Erica; Jesús Elejalde-García, Maria

    2013-08-01

    Active learning methods can be appropriate in engineering, as their methodology promotes meta-cognition, independent learning and problem-solving skills. Problem-based learning is the educational process by which problem-solving activities and instructor's guidance facilitate learning. Its key characteristic involves posing a 'concrete problem' to initiate the learning process, generally implemented by small groups of students. Many universities have developed and used active methodologies successfully in the teaching-learning process. During the past few years, the University of the Basque Country has promoted the use of active methodologies through several teacher training programmes. In this paper, we describe and analyse the results of the educational experience using the problem-based learning (PBL) method in a physics course for undergraduates enrolled in the technical telecommunications engineering degree programme. From an instructors' perspective, PBL strengths include better student attitude in class and increased instructor-student and student-student interactions. The students emphasised developing teamwork and communication skills in a good learning atmosphere as positive aspects.

  7. Systems engineering: A problem of perception

    Energy Technology Data Exchange (ETDEWEB)

    Senglaub, M.

    1995-08-01

    The characterization of systems engineering as a discipline, process, procedure or a set of heuristics will have an impact on the implementation strategy, the training methodology, and operational environment. The systems engineering upgrade activities in the New Mexico Weapons Development Center and a search of systems engineering related information provides evidence of a degree of ambiguity in this characterization of systems engineering. A case is made in this article for systems engineering being the engineering discipline applied to the science of complexity. Implications of this characterization and some generic issues are delineated with the goal of providing an enterprise with a starting point for developing its business environment.

  8. Toward Teaching Methods that Develop Learning and Enhance Problem Solving Skills in Engineering Students

    Science.gov (United States)

    Loji, K.

    2012-01-01

    Problem solving skills and abilities are critical in life and more specifically in the engineering field. Unfortunately, significant numbers of South African students who are accessing higher education lack problem solving skills and this results in poor academic performance jeopardizing their progress especially from first to second year. On the…

  9. The Implementation and Evaluation of a Project-Oriented Problem-Based Learning Module in a First Year Engineering Programme

    Science.gov (United States)

    McLoone, Seamus C.; Lawlor, Bob J.; Meehan, Andrew R.

    2016-01-01

    This paper describes how a circuits-based project-oriented problem-based learning educational model was integrated into the first year of a Bachelor of Engineering in Electronic Engineering programme at Maynooth University, Ireland. While many variations of problem based learning exist, the presented model is closely aligned with the model used in…

  10. Proceedings of the sixty-sixth annual session of Indian Institute of Chemical Engineers and joint Indo-North American symposium: oral and poster abstracts

    International Nuclear Information System (INIS)

    2013-01-01

    The aim of the symposium was to to discuss the current trends and future developments in the field of chemical engineering technology. The main themes of the symposium were: Advanced Separation Techniques; Biochemical Engineering; Process Intensification; Fossil Fuel, Nuclear and Alternate Energy; Novel Reactors and operating strategies; Green Chemistry and Engineering; Food Security; Water Treatment, Reuse and Recycle; Healthcare Technology; Nanomaterials; Process Development; Process Engineering and Control; Borderless Chemical Engineering; Fluid Mechanics and CFD; Intellectual Property Rights; Sustainable Development etc. Papers relevant to INIS are indexed separately

  11. Problem formulation for risk assessment of combined exposures to chemicals and other stressors in humans.

    Science.gov (United States)

    Solomon, Keith R; Wilks, Martin F; Bachman, Ammie; Boobis, Alan; Moretto, Angelo; Pastoor, Timothy P; Phillips, Richard; Embry, Michelle R

    2016-11-01

    When the human health risk assessment/risk management paradigm was developed, it did not explicitly include a "problem formulation" phase. The concept of problem formulation was first introduced in the context of ecological risk assessment (ERA) for the pragmatic reason to constrain and focus ERAs on the key questions. However, this need also exists for human health risk assessment, particularly for cumulative risk assessment (CRA), because of its complexity. CRA encompasses the combined threats to health from exposure via all relevant routes to multiple stressors, including biological, chemical, physical and psychosocial stressors. As part of the HESI Risk Assessment in the 21st Century (RISK21) Project, a framework for CRA was developed in which problem formulation plays a critical role. The focus of this effort is primarily on a chemical CRA (i.e., two or more chemicals) with subsequent consideration of non-chemical stressors, defined as "modulating factors" (ModFs). Problem formulation is a systematic approach that identifies all factors critical to a specific risk assessment and considers the purpose of the assessment, scope and depth of the necessary analysis, analytical approach, available resources and outcomes, and overall risk management goal. There are numerous considerations that are specific to multiple stressors, and proper problem formulation can help to focus a CRA to the key factors in order to optimize resources. As part of the problem formulation, conceptual models for exposures and responses can be developed that address these factors, such as temporal relationships between stressors and consideration of the appropriate ModFs.

  12. Applications of artificial intelligence in engineering problems. Vol. 1 and 2. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Sriram, D; Adey, R [eds.

    1986-01-01

    The purpose of the first international conference on the application of AI to engineering problems is to provide a forum for engineers all over the world to present their work on these applications. The interest being shown in the engineering community is evident by the large number of papers from the conference that are compiled into these volumes. The topics span various engineering disciplines. These topics are grouped into the following categories: - Knowledge representation and acquisition. Robotics. Natural language processing. Inexact inference techniques. General design methodologies. Constraints. Design strategies specific to a particular domain. Diagnostic systems. Intelligent front ends. Tools and techniques for building expert systems. Most of the papers deal with knowledge-based expert systems. In addition to the regular sessions, two sessions discussing a number of ongoing projects were also included in the conference. A panel on the future of AI in the engineering industry and another panel on networking were scheduled. Distinguished invited speakers from academia and industry presented lectures on their experiences with the application of AI.

  13. THE TRAVELLING SALESMAN PROBLEM IN THE ENGINEERING EDUCATION PROGRAMMING CURRICULUM

    OpenAIRE

    Yevgeny Gayev; Vadim Kalmikov

    2017-01-01

    Objective: To make students familiar with the famous Traveling Salesman Problem (TSP) and suggest the latter to become a common exercise in engineering programming curriculum provided the students master computer science in the easy programming environment MATLAB. Methods: easy programming in MATLAB makes true such modern educational approach as “discovery based” methodology. Results: a MATLAB TSP-program oriented to Ukrainian map is suggested that allows to pictorially demonstrate the proces...

  14. Lessons Learned on University Education Programs of Chemical Engineering Principles for Nuclear Plant Operations - 13588

    International Nuclear Information System (INIS)

    Ryu, Jun-hyung

    2013-01-01

    University education aims to supply qualified human resources for industries. In complex large scale engineering systems such as nuclear power plants, the importance of qualified human resources cannot be underestimated. The corresponding education program should involve many topics systematically. Recently a nuclear engineering program has been initiated in Dongguk University, South Korea. The current education program focuses on undergraduate level nuclear engineering students. Our main objective is to provide industries fresh engineers with the understanding on the interconnection of local parts and the entire systems of nuclear power plants and the associated systems. From the experience there is a huge opportunity for chemical engineering disciple in the context of giving macroscopic overview on nuclear power plant and waste treatment management by strengthening the analyzing capability of fundamental situations. (authors)

  15. Chemical engineering in fuel reprocessing. The French experience

    International Nuclear Information System (INIS)

    Viala, M.; Sombret, C.; Bernard, C.; Miquel, P.; Moulin, J.P.

    1992-01-01

    Reprocessing is the back-end of the nuclear fuel cycle, designed to recover valuable fissile materials, especially plutonium, and to condition safely all the wastes ready for disposal. For its new commercial reprocessing plants (UP 3 and UP 2 800) COGEMA decided to include many engineering innovations as well as new processes and key-components developed by CEA. UP 3 is a complete new plant with a capacity of 800 t/y which was put in operation in August 1990. UP 2 800 is an extension of the existing UP 2 facility, designed to achieve the same annual capacity of 800 t/y, to be put in operation at the end of 1993 by the commissioning of a new head-end and highly active chemical process facilities

  16. Assessing the impact on intercultural competencies when engineering students solve problems in multicultural teams

    DEFF Research Database (Denmark)

    Jensen, Lars Peter; Nygaard, Bjørn; Madsen, Linda

    2011-01-01

    solving problems in teams two times a year in all of their bachelor education. In at least four of the engineering education institutes in Denmark experiments on helping mixed student teams to perform better in their project work have been carried out for some years using a classic engineering trial......’ intercultural competencies. It was decided to start a formal research project to investigate some of the existing experiments helping mixed teams to cope with project work in intercultural teams. During spring 2010 the setup for the research project was developed by a group of representatives from...... as exchange students or to take a full degree. Project organized Problem based Learning is used to a high extent at most of the engineering educations in Denmark, using large scale project work (up to 15 ECTS each semester) solved in teams (3-7 students in each team). In more and more situations the teams...

  17. Providing Formative Assessment to Students Solving Multipath Engineering Problems with Complex Arrangements of Interacting Parts: An Intelligent Tutor Approach

    Science.gov (United States)

    Steif, Paul S.; Fu, Luoting; Kara, Levent Burak

    2016-01-01

    Problems faced by engineering students involve multiple pathways to solution. Students rarely receive effective formative feedback on handwritten homework. This paper examines the potential for computer-based formative assessment of student solutions to multipath engineering problems. In particular, an intelligent tutor approach is adopted and…

  18. Software engineering methodologies and tools

    Science.gov (United States)

    Wilcox, Lawrence M.

    1993-01-01

    Over the years many engineering disciplines have developed, including chemical, electronic, etc. Common to all engineering disciplines is the use of rigor, models, metrics, and predefined methodologies. Recently, a new engineering discipline has appeared on the scene, called software engineering. For over thirty years computer software has been developed and the track record has not been good. Software development projects often miss schedules, are over budget, do not give the user what is wanted, and produce defects. One estimate is there are one to three defects per 1000 lines of deployed code. More and more systems are requiring larger and more complex software for support. As this requirement grows, the software development problems grow exponentially. It is believed that software quality can be improved by applying engineering principles. Another compelling reason to bring the engineering disciplines to software development is productivity. It has been estimated that productivity of producing software has only increased one to two percent a year in the last thirty years. Ironically, the computer and its software have contributed significantly to the industry-wide productivity, but computer professionals have done a poor job of using the computer to do their job. Engineering disciplines and methodologies are now emerging supported by software tools that address the problems of software development. This paper addresses some of the current software engineering methodologies as a backdrop for the general evaluation of computer assisted software engineering (CASE) tools from actual installation of and experimentation with some specific tools.

  19. Model Reduction in Chemical Engineering : Case studies applied to process analysis, design and operation

    NARCIS (Netherlands)

    Dorneanu, B.

    2011-01-01

    During the last decades, models have become widely used for supporting a broad range of chemical engineering activities, such as product and process design and development, process monitoring and control, real time optimization of plant operation or supply chain management. Although tremendous

  20. Holographic black hole engineering at finite baryon chemical potential

    International Nuclear Information System (INIS)

    Rougemont, Romulo

    2017-01-01

    This is a contribution for the Proceedings of the Conference Hot Quarks 2016, held at South Padre Island, Texas, USA, 12-17 September 2016. I briefly review some thermodynamic and baryon transport results obtained from a bottom-up Einstein-Maxwell-Dilaton holographic model engineered to describe the physics of the quark-gluon plasma at finite temperature and baryon density. The results for the equation of state, baryon susceptibilities, and the curvature of the crossover band are in quantitative agreement with the corresponding lattice QCD results with 2 + 1 flavors and physical quark masses. Baryon diffusion is predicted to be suppressed by increasing the baryon chemical potential. (paper)

  1. Uncertainty Quantification with Applications to Engineering Problems

    DEFF Research Database (Denmark)

    Bigoni, Daniele

    in measurements, predictions and manufacturing, and we can say that any dynamical system used in engineering is subject to some of these uncertainties. The first part of this work presents an overview of the mathematical framework used in Uncertainty Quantification (UQ) analysis and introduces the spectral tensor...... and thus the UQ analysis of the associated systems will benefit greatly from the application of methods which require few function evaluations. We first consider the propagation of the uncertainty and the sensitivity analysis of the non-linear dynamics of railway vehicles with suspension components whose......-scale problems, where efficient methods are necessary with today’s computational resources. The outcome of this work was also the creation of several freely available Python modules for Uncertainty Quantification, which are listed and described in the appendix....

  2. Dam construction as an engineering solution for water supply problem : environmental thrusts

    Energy Technology Data Exchange (ETDEWEB)

    Hosseini, A.H. [Alberta Univ., Edmonton, AB (Canada). Dept. of Civil and Environmental Engineering

    2004-09-01

    Water supply management and the potential impacts associated with engineering practices in water supply systems were examined. Global aspects of increasing water demand were presented and compared with populations, urbanization and water demand. Engineering practices in waterworks developments such as dam construction, river intakes, infiltration galleries, wells, boreholes and adits were also discussed. Construction of large dams and the problems associated with damming the rivers were studied as large dams generally have substantial impacts on rivers, watersheds and aquatic ecosystems, leading to the irreversible loss of species populations and ecosystems. These problems include negative impacts on the terrestrial ecosystem, greenhouse gas emissions from reservoirs due to decaying vegetation and carbon inflows from the catchment, changes in flow regimes, trapping of sediments and nutrients behind a dam, blocking migration of aquatic organisms, as well as negative impacts on flood plain ecosystems and fisheries. In addition, a case study, on the environmental impacts associated with damming in Three Gorges Valley in China was presented. 9 refs., 8 figs.

  3. A Typology of Engineering Designs in Problem-Based Projects

    DEFF Research Database (Denmark)

    Larsen, Samuel Brüning; Bigum, Per Valentin

    include a set of general characteristics of great engineering solutions and a typology of three solution archetypes. The study labels these archetypes as 1) the adapted solution, 2) the “either/or”-solution, and 3) the multiple-elements solution. For each archetype, the paper specifies the corresponding...... class of problems that the archetype can logically address. In addition, the paper delineates (1) how each archetype relates to a project’s analysis and (2) how each archetype is evaluated, implemented and operated. The typology aids both students and project supervisors in conducting reports...

  4. Chemical cleaning the service water system at a nuclear power plant

    International Nuclear Information System (INIS)

    Brice, T.O.; Glover, W.A.

    1994-01-01

    Chemical cleaning a large cooling water system in a nuclear power plant presented many unique problems. The selection, qualification, and performance of the cleaning process were done using a phased approach. The piping was inspected to determine the extent of the problem. Deposit samples were removed from the service water system pipe and tested in the laboratory to determine the most effective cleaning solvent for deposit removal. An engineering study was performed to define the design parameters required to implement the system-wide chemical cleaning

  5. SC: A NOVEL FUZZY CRITERION FOR SOLVING ENGINEERING AND CONSTRAINED OPTIMIZATION PROBLEMS

    Directory of Open Access Journals (Sweden)

    Sergio G. De los Cobos Silva

    2017-04-01

    Full Text Available In this paper a novel fuzzy convergence system (SC and its fundamentals are presented. The model was implemented on a monoobjetive PSO algorithm with three phases: 1 Stabilization, 2 generation and breadth-first search, and 3 generation and depth-first. The system SC-PSO-3P was tested with several benchmark engineering problems and with several CEC2006 problems. The computing experience and comparison with previously reported results is presented. In some cases the results reported in the literature are improved.

  6. Activist engineering: changing engineering practice by deploying praxis.

    Science.gov (United States)

    Karwat, Darshan M A; Eagle, Walter E; Wooldridge, Margaret S; Princen, Thomas E

    2015-02-01

    In this paper, we reflect on current notions of engineering practice by examining some of the motives for engineered solutions to the problem of climate change. We draw on fields such as science and technology studies, the philosophy of technology, and environmental ethics to highlight how dominant notions of apoliticism and ahistoricity are ingrained in contemporary engineering practice. We argue that a solely technological response to climate change does not question the social, political, and cultural tenet of infinite material growth, one of the root causes of climate change. In response to the contemporary engineering practice, we define an activist engineer as someone who not only can provide specific engineered solutions, but who also steps back from their work and tackles the question, What is the real problem and does this problem "require" an engineering intervention? Solving complex problems like climate change requires radical cultural change, and a significant obstacle is educating engineers about how to conceive of and create "authentic alternatives," that is, solutions that differ from the paradigm of "technologically improving" our way out of problems. As a means to realize radically new solutions, we investigate how engineers might (re)deploy the concept of praxis, which raises awareness in engineers of the inherent politics of technological design. Praxis empowers engineers with a more comprehensive understanding of problems, and thus transforms technologies, when appropriate, into more socially just and ecologically sensitive interventions. Most importantly, praxis also raises a radical alternative rarely considered-not "engineering a solution." Activist engineering offers a contrasting method to contemporary engineering practice and leads toward social justice and ecological protection through problem solving by asking not, How will we technologize our way out of the problems we face? but instead, What really needs to be done?

  7. Developing Creativity and Problem-Solving Skills of Engineering Students: A Comparison of Web- and Pen-and-Paper-Based Approaches

    Science.gov (United States)

    Valentine, Andrew; Belski, Iouri; Hamilton, Margaret

    2017-01-01

    Problem-solving is a key engineering skill, yet is an area in which engineering graduates underperform. This paper investigates the potential of using web-based tools to teach students problem-solving techniques without the need to make use of class time. An idea generation experiment involving 90 students was designed. Students were surveyed…

  8. Development Of Entrepreneur Learning Model Based On Problem Based Learning To Increase Competency Independence And Creativity Students Of Industrial Engineering

    Directory of Open Access Journals (Sweden)

    Leola Dewiyani

    2017-10-01

    Full Text Available Currently it is undeniable that the competition to get a job is very tight and of course universities have an important role in printing human resources that can compete globally not least with the Department of Industrial Engineering Faculty of Engineering Muhammadiyah University of Jakarta FT UMJ. Problems that occur is based on the analysis obtained from the track record of graduates researchers found that 60 percent of students of Industrial Engineering FT UMJ work not in accordance with the level of education owned so financially their income is still below the standard. This study aims to improve the competence of students of Industrial Engineering Department FT UMJ in entrepreneurship courses especially through the development of Problem Based Learning based learning model. Specific targets of this research were conducted with the aim to identify and analyze the need to implement learning model based on Problem Based Learning Entrepreneurship and to design and develop the model of entrepreneurship based on Problem Based Learning to improve the competence independence and creativity of Industrial Engineering students of FT UMJ in Entrepreneurship course. To achieve the above objectives this research uses research and development R amp D method. The product produced in this research is the detail of learning model of entrepreneurial model based on Problem Based Learning entrepreneurship model based on Problem Based Learning and international journals

  9. Physically - engineering problems of the Salaspils Nuclear reactor: Solutions and their topicality

    International Nuclear Information System (INIS)

    Mozgirs, Z.V.

    2005-01-01

    The paper generalizes technical solutions of physically-engineering problems of the Salaspils nuclear research reactor, experience of its modernization and exploitation. New equipment and the related technical solutions have been tested at the Salaspils reactor during its operation time and are now recommended for further use at nuclear reactors. (author)

  10. Integrating Sustainable Development in Chemical Engineering Education: The Application of an Environmental Management System

    Science.gov (United States)

    Montanes, M. T.; Palomares, A. E.; Sanchez-Tovar, R.

    2012-01-01

    The principles of sustainable development have been integrated in chemical engineering education by means of an environmental management system. These principles have been introduced in the teaching laboratories where students perform their practical classes. In this paper, the implementation of the environmental management system, the problems…

  11. The Problem-Solving Process in Physics as Observed When Engineering Students at University Level Work in Groups

    Science.gov (United States)

    Gustafsson, Peter; Jonsson, Gunnar; Enghag, Margareta

    2015-01-01

    The problem-solving process is investigated for five groups of students when solving context-rich problems in an introductory physics course included in an engineering programme. Through transcripts of their conversation, the paths in the problem-solving process have been traced and related to a general problem-solving model. All groups exhibit…

  12. Mimicking Neurotransmitter Release in Chemical Synapses via Hysteresis Engineering in MoS2 Transistors.

    Science.gov (United States)

    Arnold, Andrew J; Razavieh, Ali; Nasr, Joseph R; Schulman, Daniel S; Eichfeld, Chad M; Das, Saptarshi

    2017-03-28

    Neurotransmitter release in chemical synapses is fundamental to diverse brain functions such as motor action, learning, cognition, emotion, perception, and consciousness. Moreover, improper functioning or abnormal release of neurotransmitter is associated with numerous neurological disorders such as epilepsy, sclerosis, schizophrenia, Alzheimer's disease, and Parkinson's disease. We have utilized hysteresis engineering in a back-gated MoS 2 field effect transistor (FET) in order to mimic such neurotransmitter release dynamics in chemical synapses. All three essential features, i.e., quantal, stochastic, and excitatory or inhibitory nature of neurotransmitter release, were accurately captured in our experimental demonstration. We also mimicked an important phenomenon called long-term potentiation (LTP), which forms the basis of human memory. Finally, we demonstrated how to engineer the LTP time by operating the MoS 2 FET in different regimes. Our findings could provide a critical component toward the design of next-generation smart and intelligent human-like machines and human-machine interfaces.

  13. Scientific and technical conference. Problems and horizons of development of chemical and radiochemical control in nuclear energetics. Collection of summaries of reports

    International Nuclear Information System (INIS)

    2001-01-01

    During scientific and technical conference on problems of development of chemical and radiochemical control in nuclear energetics following themes were considered: the problems of methodological and instrumental assurance of chemical and radiochemical control at working nuclear power plants and nuclear energetic units; modern conceptions of automation systems construction of chemical and radiochemical control on the basis of intellectual measuring channels; the ways of decision of generally system problems of organization and management of chemical and radiochemical control using computed technologies; the problems of certification of chemical and radiochemical methods of measuring in nuclear energetics [ru

  14. Differences in Chemical Engineering Student-Faculty Interactions by Student Age and Experience at a Large, Public, Research University

    Science.gov (United States)

    Ciston, Shannon; Sehgal, Sanya; Mikel, Tressa; Carnasciali, Maria-Isabel

    2018-01-01

    Adult undergraduate students aged 25+ in engineering disciplines are an important demographic bringing a wealth of life experience to the classroom. This study uses qualitative data drawn from semi-structured interviews with two groups of undergraduate chemical engineering students at a large, public research university: adult students with…

  15. Training of innovative engineers for problems of modernization of a domestic production

    Directory of Open Access Journals (Sweden)

    Brusakova I.

    2017-01-01

    Full Text Available The actual problem of training of innovative managers for problems of modernization of a domestic production is considered in research. Practice of application of innovative engineering in the sphere of modernization of industrial productions is studied. The perspective of an integrated approach to management of innovative processes is investigated, including competence-based approach to training of innovative managers and modern instruments of management of finance innovative business - processes. Authors offered new approaches to formation of innovative capacity of the domestic industrial enterprises. Different ways of innovation creation are discussing.

  16. Design of chemical plant

    International Nuclear Information System (INIS)

    Lee, Dong Il; Kim, Seung Jae; Yang, Jae Ho; Ryu, Hwa Won

    1993-01-01

    This book describes design of chemical plant, which includes chemical engineer and plan for chemical plant, development of chemical process, cost engineering pattern, design and process development, general plant construction plan, project engineering, foundation for economy on assets and depreciation, estimation for cost on capital investment and manufacturing cost, design with computers optimal design and method like fluid mechanics design chemical device and estimation for cost, such as dispatch of material and device writing on design report and appendixes.

  17. Using Green Chemistry and Engineering Principles to Design, Assess, and Retrofit Chemical Processes for Sustainability

    Science.gov (United States)

    The concepts of green chemistry and engineering (GC&E) have been promoted as an effective qualitative framework for developing more sustainable chemical syntheses, processes, and material management techniques. This has been demonstrated by many theoretical and practical cases. I...

  18. Under pressure: evolutionary engineering of yeast strains for improved performance in fuels and chemicals production

    NARCIS (Netherlands)

    Mans, R.; Daran, J.G.; Pronk, J.T.

    2018-01-01

    Evolutionary engineering, which uses laboratory evolution to select for industrially relevant traits, is a popular strategy in the development of high-performing yeast strains for industrial production of fuels and chemicals. By integrating whole-genome sequencing, bioinformatics, classical

  19. Hybrid intelligent optimization methods for engineering problems

    Science.gov (United States)

    Pehlivanoglu, Yasin Volkan

    The purpose of optimization is to obtain the best solution under certain conditions. There are numerous optimization methods because different problems need different solution methodologies; therefore, it is difficult to construct patterns. Also mathematical modeling of a natural phenomenon is almost based on differentials. Differential equations are constructed with relative increments among the factors related to yield. Therefore, the gradients of these increments are essential to search the yield space. However, the landscape of yield is not a simple one and mostly multi-modal. Another issue is differentiability. Engineering design problems are usually nonlinear and they sometimes exhibit discontinuous derivatives for the objective and constraint functions. Due to these difficulties, non-gradient-based algorithms have become more popular in recent decades. Genetic algorithms (GA) and particle swarm optimization (PSO) algorithms are popular, non-gradient based algorithms. Both are population-based search algorithms and have multiple points for initiation. A significant difference from a gradient-based method is the nature of the search methodologies. For example, randomness is essential for the search in GA or PSO. Hence, they are also called stochastic optimization methods. These algorithms are simple, robust, and have high fidelity. However, they suffer from similar defects, such as, premature convergence, less accuracy, or large computational time. The premature convergence is sometimes inevitable due to the lack of diversity. As the generations of particles or individuals in the population evolve, they may lose their diversity and become similar to each other. To overcome this issue, we studied the diversity concept in GA and PSO algorithms. Diversity is essential for a healthy search, and mutations are the basic operators to provide the necessary variety within a population. After having a close scrutiny of the diversity concept based on qualification and

  20. Perceived health problems in swimmers according to the chemical treatment of water in swimming pools.

    Science.gov (United States)

    Fernández-Luna, Álvaro; Burillo, Pablo; Felipe, José Luis; del Corral, Julio; García-Unanue, Jorge; Gallardo, Leonor

    2016-01-01

    The objective of this study was to determine which chemical treatment used for disinfecting water in indoor swimming pools had the least impact on users' perceptions of health problems, and which generated the greatest satisfaction with the quality of the water. A survey on satisfaction and perceived health problems was given to 1001 users at 20 indoor swimming pools which used different water treatment methods [chlorine, bromine, ozone, ultraviolet lamps (UV) and salt electrolysis]. The findings suggest that there is a greater probability of perceived health problems, such as eye and skin irritation, respiratory problems and skin dryness, in swimming pools treated with chlorine than in swimming pools using other chemical treatment methods. Pools treated with bromine have similar, although slightly better, results. Other factors, such as age, gender, time of day of use (morning and afternoon) and type of user (competitive and recreational), can also affect the probability of suffering health problems. For all of the above, using combined treatment methods as ozone and UV, or salt electrolysis produces a lower probability of perceived health problems and greater satisfaction.

  1. Modeling Complex Chemical Systems: Problems and Solutions

    Science.gov (United States)

    van Dijk, Jan

    2016-09-01

    Non-equilibrium plasmas in complex gas mixtures are at the heart of numerous contemporary technologies. They typically contain dozens to hundreds of species, involved in hundreds to thousands of reactions. Chemists and physicists have always been interested in what are now called chemical reduction techniques (CRT's). The idea of such CRT's is that they reduce the number of species that need to be considered explicitly without compromising the validity of the model. This is usually achieved on the basis of an analysis of the reaction time scales of the system under study, which identifies species that are in partial equilibrium after a given time span. The first such CRT that has been widely used in plasma physics was developed in the 1960's and resulted in the concept of effective ionization and recombination rates. It was later generalized to systems in which multiple levels are effected by transport. In recent years there has been a renewed interest in tools for chemical reduction and reaction pathway analysis. An example of the latter is the PumpKin tool. Another trend is that techniques that have previously been developed in other fields of science are adapted as to be able to handle the plasma state of matter. Examples are the Intrinsic Low Dimension Manifold (ILDM) method and its derivatives, which originate from combustion engineering, and the general-purpose Principle Component Analysis (PCA) technique. In this contribution we will provide an overview of the most common reduction techniques, then critically assess the pros and cons of the methods that have gained most popularity in recent years. Examples will be provided for plasmas in argon and carbon dioxide.

  2. Ground based measurements of particulate emissions from supersonic transports. Concorde olympus engine

    Energy Technology Data Exchange (ETDEWEB)

    Whitefield, Ph D; Hagen, D E [Missouri Univ., Rolla, MO (United States). Cloud and Aerosol Sciences Lab.; Lilenfeld, H V [McDonnell Douglas Corp., St. Louis, MO (United States)

    1998-12-31

    The application of a mobile aerosol monitoring facility, the Mobile Aerosol Sampling System (MASS) is described to characterize engine aerosol emissions from the Rolls Royce Olympus Engine. The multi-configurational MASS has been employed in both ground and airborne field operations. It has been successfully flown on research aircrafts. In ground tests the MASS has participated in numerous jet engine related ground tests, and has been deployed to resolve aerosol generation problems in a high power chemical laser system. In all cases the measurements were made on samples taken from a harsh physical and chemical environment, with both high and low temperature and pressure, and in the presence of highly reactive gases. (R.P.) 9 refs.

  3. Ground based measurements of particulate emissions from supersonic transports. Concorde olympus engine

    Energy Technology Data Exchange (ETDEWEB)

    Whitefield, Ph.D.; Hagen, D.E. [Missouri Univ., Rolla, MO (United States). Cloud and Aerosol Sciences Lab.; Lilenfeld, H.V. [McDonnell Douglas Corp., St. Louis, MO (United States)

    1997-12-31

    The application of a mobile aerosol monitoring facility, the Mobile Aerosol Sampling System (MASS) is described to characterize engine aerosol emissions from the Rolls Royce Olympus Engine. The multi-configurational MASS has been employed in both ground and airborne field operations. It has been successfully flown on research aircrafts. In ground tests the MASS has participated in numerous jet engine related ground tests, and has been deployed to resolve aerosol generation problems in a high power chemical laser system. In all cases the measurements were made on samples taken from a harsh physical and chemical environment, with both high and low temperature and pressure, and in the presence of highly reactive gases. (R.P.) 9 refs.

  4. The Navy/NASA Engine Program (NNEP89): Interfacing the program for the calculation of complex Chemical Equilibrium Compositions (CEC)

    Science.gov (United States)

    Gordon, Sanford

    1991-01-01

    The NNEP is a general computer program for calculating aircraft engine performance. NNEP has been used extensively to calculate the design and off-design (matched) performance of a broad range of turbine engines, ranging from subsonic turboprops to variable cycle engines for supersonic transports. Recently, however, there has been increased interest in applications for which NNEP is not capable of simulating, such as the use of alternate fuels including cryogenic fuels and the inclusion of chemical dissociation effects at high temperatures. To overcome these limitations, NNEP was extended by including a general chemical equilibrium method. This permits consideration of any propellant system and the calculation of performance with dissociation effects. The new extended program is referred to as NNEP89.

  5. Expanding the chemical diversity of natural esters by engineering a polyketide-derived pathway into Escherichia coli.

    Science.gov (United States)

    Menendez-Bravo, Simón; Comba, Santiago; Sabatini, Martín; Arabolaza, Ana; Gramajo, Hugo

    2014-07-01

    Microbial fatty acid (FA)-derived molecules have emerged as promising alternatives to petroleum-based chemicals for reducing dependence on fossil hydrocarbons. However, native FA biosynthetic pathways often yield limited structural diversity, and therefore restricted physicochemical properties, of the end products by providing only a limited variety of usually linear hydrocarbons. Here we have engineered into Escherichia coli a mycocerosic polyketide synthase-based biosynthetic pathway from Mycobacterium tuberculosis and redefined its biological role towards the production of multi-methyl-branched-esters (MBEs) with novel chemical structures. Expression of FadD28, Mas and PapA5 enzymes enabled the biosynthesis of multi-methyl-branched-FA and their further esterification to an alcohol. The high substrate tolerance of these enzymes towards different FA and alcohol moieties resulted in the biosynthesis of a broad range of MBE. Further metabolic engineering of the MBE producer strain coupled this system to long-chain-alcohol biosynthetic pathways resulting in de novo production of branched wax esters following addition of only propionate. Copyright © 2014 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  6. The international symposium on 'chemical engineering of gas-liquid-solid catalyst reactions'

    Energy Technology Data Exchange (ETDEWEB)

    Hammer, H

    1978-06-01

    A report on the International Symposium on ''Chemical Engineering of Gas-Liquid-Solid Catalyst Reactions'', sponsored by the University of Liege (3/2-3/78), covers papers on the hydrodynamics, modeling and simulation, operating behavior, and chemical kinetics of trickle-bed reactors; scale-up of a trickle-bed reactor for hydrotreating Kuwait vacuum distillate; experimental results obtained in trickle-bed reactors for hydroprocessing atmospheric residua, hydrogenation of methylstyrene, hydrogenation of butanone, and hydrodemetallization of petroleum residua; advantages and disadvantages of various three-phase reactor types (e.g., for the liquid-phase hydrogenation of carbon monoxide to benzene, SNG, or methanol) and hydrodynamics, mass and heat transfer, and modeling of bubble columns with suspended catalysts (slurry reactors), and their applications (e.g., in SNG and fermentation processes).

  7. HYPER-­TVT: Development and Implementation of an Interactive Learning Environment for Students of Chemical and Process Engineering

    Science.gov (United States)

    Santoro, Marina; Mazzotti, Marco

    2006-01-01

    Hyper-TVT is a computer-aided education system that has been developed at the Institute of Process Engineering at the ETH Zurich. The aim was to create an interactive learning environment for chemical and process engineering students. The topics covered are the most important multistage separation processes, i.e. fundamentals of separation…

  8. Grand Challenges and Chemical Engineering Curriculum--Developments at TU Dortmund University

    Science.gov (United States)

    Kockmann, Norbert; Lutze, Philip; Gorak, Andrzej

    2016-01-01

    Chemical processing industry is progressively focusing their research activities and product placements in the areas of Grand Challenges (or Global Megatrends) such as mobility, energy, communication, or health care and food. Innovation in all these fields requires solving high complex problems, rapid product development as well as dealing with…

  9. Research on Life Science and Life Support Engineering Problems of Manned Deep Space Exploration Mission

    Science.gov (United States)

    Qi, Bin; Guo, Linli; Zhang, Zhixian

    2016-07-01

    Space life science and life support engineering are prominent problems in manned deep space exploration mission. Some typical problems are discussed in this paper, including long-term life support problem, physiological effect and defense of varying extraterrestrial environment. The causes of these problems are developed for these problems. To solve these problems, research on space life science and space medical-engineering should be conducted. In the aspect of space life science, the study of space gravity biology should focus on character of physiological effect in long term zero gravity, co-regulation of physiological systems, impact on stem cells in space, etc. The study of space radiation biology should focus on target effect and non-target effect of radiation, carcinogenicity of radiation, spread of radiation damage in life system, etc. The study of basic biology of space life support system should focus on theoretical basis and simulating mode of constructing the life support system, filtration and combination of species, regulation and optimization method of life support system, etc. In the aspect of space medical-engineering, the study of bio-regenerative life support technology should focus on plants cultivation technology, animal-protein production technology, waste treatment technology, etc. The study of varying gravity defense technology should focus on biological and medical measures to defend varying gravity effect, generation and evaluation of artificial gravity, etc. The study of extraterrestrial environment defense technology should focus on risk evaluation of radiation, monitoring and defending of radiation, compound prevention and removal technology of dust, etc. At last, a case of manned lunar base is analyzed, in which the effective schemes of life support system, defense of varying gravity, defense of extraterrestrial environment are advanced respectively. The points in this paper can be used as references for intensive study on key

  10. Applications of hybrid and digital computation methods in aerospace-related sciences and engineering. [problem solving methods at the University of Houston

    Science.gov (United States)

    Huang, C. J.; Motard, R. L.

    1978-01-01

    The computing equipment in the engineering systems simulation laboratory of the Houston University Cullen College of Engineering is described and its advantages are summarized. The application of computer techniques in aerospace-related research psychology and in chemical, civil, electrical, industrial, and mechanical engineering is described in abstracts of 84 individual projects and in reprints of published reports. Research supports programs in acoustics, energy technology, systems engineering, and environment management as well as aerospace engineering.

  11. Engineering propionibacteria as versatile cell factories for the production of industrially important chemicals: advances, challenges, and prospects.

    Science.gov (United States)

    Guan, Ningzi; Zhuge, Xin; Li, Jianghua; Shin, Hyun-Dong; Wu, Jing; Shi, Zhongping; Liu, Long

    2015-01-01

    Propionibacteria are actinobacteria consisting of two principal groups: cutaneous and dairy. Cutaneous propionibacteria are considered primary pathogens to humans, whereas dairy propionibacteria are widely used in the food and pharmaceutical industries. Increasing attention has been focused on improving the performance of dairy propionibacteria for the production of industrially important chemicals, and significant advances have been made through strain engineering and process optimization in the production of flavor compounds, nutraceuticals, and antimicrobial compounds. In addition, genome sequencing of several propionibacteria species has been completed, deepening understanding of the metabolic and physiological features of these organisms. However, the metabolic engineering of propionibacteria still faces several challenges owing to the lack of efficient genome manipulation tools and the existence of various types of strong restriction-modification systems. The emergence of systems and synthetic biology provides new opportunities to overcome these bottlenecks. In this review, we first introduce the major species of propionibacteria and their properties and provide an overview of their functions and applications. We then discuss advances in the genome sequencing and metabolic engineering of these bacteria. Finally, we discuss systems and synthetic biology approaches for engineering propionibacteria as efficient and robust cell factories for the production of industrially important chemicals.

  12. Understanding ill-structured engineering ethics problems through a collaborative learning and argument visualization approach.

    Science.gov (United States)

    Hoffmann, Michael; Borenstein, Jason

    2014-03-01

    As a committee of the National Academy of Engineering recognized, ethics education should foster the ability of students to analyze complex decision situations and ill-structured problems. Building on the NAE's insights, we report about an innovative teaching approach that has two main features: first, it places the emphasis on deliberation and on self-directed, problem-based learning in small groups of students; and second, it focuses on understanding ill-structured problems. The first innovation is motivated by an abundance of scholarly research that supports the value of deliberative learning practices. The second results from a critique of the traditional case-study approach in engineering ethics. A key problem with standard cases is that they are usually described in such a fashion that renders the ethical problem as being too obvious and simplistic. The practitioner, by contrast, may face problems that are ill-structured. In the collaborative learning environment described here, groups of students use interactive and web-based argument visualization software called "AGORA-net: Participate - Deliberate!". The function of the software is to structure communication and problem solving in small groups. Students are confronted with the task of identifying possible stakeholder positions and reconstructing their legitimacy by constructing justifications for these positions in the form of graphically represented argument maps. The argument maps are then presented in class so that these stakeholder positions and their respective justifications become visible and can be brought into a reasoned dialogue. Argument mapping provides an opportunity for students to collaborate in teams and to develop critical thinking and argumentation skills.

  13. Problems the chemical industry of Japan faces and future prospects

    Energy Technology Data Exchange (ETDEWEB)

    Ishida, Shin' ichi

    1989-01-01

    Industry proceeds for the fiscal 1988 are expected to increase remarkably as they did in the previous year with 4.9% increase in revenue and 18.8% increase in profit (ordinary profit) from the previous year. The conditions of material industry are especially favorable and chemical industry is also expected to prosper as it did in the previous year. Problems this prospering chemical industry is facing are introduced in this report. Firstly, it is necessary to improve productivity by adopting more information and promoting factory automation in order to strengthen competition. The future of chemical industry depends on the introduction of information. Secondly, as demands of users are becoming more diversified, and cycles of products shorter, shortening of development terms is essential. It is necessary, therefore, to predict the demands of users in advance and seek after custom products. Thirdly, selection of product bases is required; it might be necessary to consider producing some product items abroad. Moreover, it is desirable to increase investments in investigation and pursue creativity putting much stress on basic investigations. 2 figs., 11 tabs.

  14. Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks

    DEFF Research Database (Denmark)

    Chen, Yun; Nielsen, Jens

    2013-01-01

    Bio-based production of chemical building blocks from renewable resources is an attractive alternative to petroleum-based platform chemicals. Metabolic pathway and strain engineering is the key element in constructing robust microbial chemical factories within the constraints of cost effective...... production. Here we discuss how the development of computational algorithms, novel modules and methods, omics-based techniques combined with modeling refinement are enabling reduction in development time and thus advance the field of industrial biotechnology. We further discuss how recent technological...

  15. Modeling and simulation of different and representative engineering problems using Network Simulation Method.

    Science.gov (United States)

    Sánchez-Pérez, J F; Marín, F; Morales, J L; Cánovas, M; Alhama, F

    2018-01-01

    Mathematical models simulating different and representative engineering problem, atomic dry friction, the moving front problems and elastic and solid mechanics are presented in the form of a set of non-linear, coupled or not coupled differential equations. For different parameters values that influence the solution, the problem is numerically solved by the network method, which provides all the variables of the problems. Although the model is extremely sensitive to the above parameters, no assumptions are considered as regards the linearization of the variables. The design of the models, which are run on standard electrical circuit simulation software, is explained in detail. The network model results are compared with common numerical methods or experimental data, published in the scientific literature, to show the reliability of the model.

  16. Effect of Continuous Assessment on Learning Outcomes on Two Chemical Engineering Courses: Case Study

    Science.gov (United States)

    Tuunila, R.; Pulkkinen, M.

    2015-01-01

    In this paper, the effect of continuous assessment on the learning outcomes of two chemical engineering courses is studied over a several-year period. Average grades and passing percentages of courses after the final examination are reported and also student feedback on the courses is collected. The results indicate significantly better learning…

  17. NATO Advanced Research Workshop on Chemical Instabilities : Applications in Chemistry, Engineering, Geology, and Materials Science

    CERN Document Server

    Baras, F

    1984-01-01

    On March 14-18, 1983 a workshop on "Chemical Instabilities: Applications in Chemistry, Engineering, Geology, and Materials Science" was held in Austin, Texas, U.S.A. It was organized jointly by the University of Texas at Austin and the Universite Libre de Bruxelles and sponsored qy NATO, NSF, the University of Texas at Austin, the International Solvay Institutes and the Ex­ xon Corporation. The present Volume includes most of the material of the in­ vited lectures delivered in the workshop as well as material from some posters, whose content was directly related to the themes of the invited lectures. In ,recent years, problems related to the stability and the nonlinear dynamics of nonequilibrium systems invaded a great num­ ber of fields ranging from abstract mathematics to biology. One of the most striking aspects of this development is that subjects reputed to be "classical" and "well-established" like chemistry, turned out to give rise to a rich variety of phenomena leading to multiple steady states and...

  18. Oxygen sensor equipped engine operation on methanol/gasoline blends and phase separation problems

    Energy Technology Data Exchange (ETDEWEB)

    Last, A J; Lawson, A; Simmons, E W; Mackay, D; Tsang, M; Maund, G B

    1980-01-01

    A study was made to address problems related to Canadian utilization of methanol/gasoline blends. These problems are: (1) cold weather operation; (2) water sensitivity to phase separation in winter; (3) vehicle compatibility: fuel/air ratio control, flexibility for vehicle movement outside of areas where methanol might be available. Specifically, the operation of the HydroShear (an in-line hydraulic emulsifier) on the two separated phases of a methanol/gasoline/water blend was examined. Fuel maps, by engine dynamometer testing, were generated using methanol/gasoline blends containing 15% to 65% methanol. The capability of an oxygen sensor, located in the exhaust system, to control the fuel/air ratio was found to be adequate within the 15% to 65% methanol/gasoline blends. A fuel injected Volvo 244DL with lambda-sond emission control and a carburetted Chevrolet Monza with 3-way catalyst closed loop feedback emission control system were the two engines selected for this study.

  19. Molecular Modeling as a Self-Taught Component of a Conventional Undergraduate Chemical Reaction Engineering Course

    Science.gov (United States)

    Rothe, Erhard W.; Zygmunt, William E.

    2016-01-01

    We inserted a self-taught molecular modeling project into an otherwise conventional undergraduate chemical-reaction-engineering course. Our objectives were that students should (a) learn with minimal instructor intervention, (b) gain an appreciation for the relationship between molecular structure and, first, macroscopic state functions in…

  20. Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes 1st edition (Preface)

    Science.gov (United States)

    This book preface explains the needs found by the book editors for assembling the state of the art of technical and scientific knowledge relevant to chemical engineering, sustainability, and sustainable uses of wastes and materials management, and to do so in an accessible and c...

  1. Chemical engineering and structural and pharmacological characterization of the α-scorpion toxin OD1.

    Science.gov (United States)

    Durek, Thomas; Vetter, Irina; Wang, Ching-I Anderson; Motin, Leonid; Knapp, Oliver; Adams, David J; Lewis, Richard J; Alewood, Paul F

    2013-01-01

    Scorpion α-toxins are invaluable pharmacological tools for studying voltage-gated sodium channels, but few structure-function studies have been undertaken due to their challenging synthesis. To address this deficiency, we report a chemical engineering strategy based upon native chemical ligation. The chemical synthesis of α-toxin OD1 was achieved by chemical ligation of three unprotected peptide segments. A high resolution X-ray structure (1.8 Å) of synthetic OD1 showed the typical βαββ α-toxin fold and revealed important conformational differences in the pharmacophore region when compared with other α-toxin structures. Pharmacological analysis of synthetic OD1 revealed potent α-toxin activity (inhibition of fast inactivation) at Nav1.7, as well as Nav1.4 and Nav1.6. In addition, OD1 also produced potent β-toxin activity at Nav1.4 and Nav1.6 (shift of channel activation in the hyperpolarizing direction), indicating that OD1 might interact at more than one site with Nav1.4 and Nav1.6. Investigation of nine OD1 mutants revealed that three residues in the reverse turn contributed significantly to selectivity, with the triple OD1 mutant (D9K, D10P, K11H) being 40-fold more selective for Nav1.7 over Nav1.6, while OD1 K11V was 5-fold more selective for Nav1.6 than Nav1.7. This switch in selectivity highlights the importance of the reverse turn for engineering α-toxins with altered selectivity at Nav subtypes.

  2. The Chemical Technology Division at Argonne National Laboratory: Applying chemical innovation to environmental problems

    International Nuclear Information System (INIS)

    1995-01-01

    The Chemical Technology Division is one of the largest technical divisions at Argonne National Laboratory, a leading center for research and development related to energy and environmental issues. Since its inception in 1948, the Division has pioneered in developing separations processes for the nuclear industry. The current scope of activities includes R ampersand D on methods for disposing of radioactive and hazardous wastes and on energy conversion processes with improved efficiencies, lower costs, and reduced environmental impact. Many of the technologies developed by CMT can be applied to solve manufacturing as well as environmental problems of industry

  3. Personalized Education Approaches for Chemical Engineering and Relevant Majors

    Directory of Open Access Journals (Sweden)

    Zhao Feng-qing

    2016-01-01

    Full Text Available Personalized education has drawn increasing attention in universities these years. With the purpose of improving the studentss’ comprehensive ability and developing teaching strategies to ensure students’ education is tailored to their needs, we proposed Three-Stage Approach (TSA to enhance personalized education for chemical engineering and relevant majors: professional tutorial system--equipping with professional guidance teachers for freshman students to guide their learning activities and provide professional guidance; open experimental project--setting up open experimental projects for sophomore and junior students to choose freely; individualized education module--setting up 10 different individualized education modules for senior students to select. After years of practice, the personalized education model is improved day by day and proved effective and fruitful.

  4. Basic transport phenomena in materials engineering

    CERN Document Server

    Iguchi, Manabu

    2014-01-01

    This book presents the basic theory and experimental techniques of transport phenomena in materials processing operations. Such fundamental knowledge is highly useful for researchers and engineers in the field to improve the efficiency of conventional processes or develop novel technology. Divided into four parts, the book comprises 11 chapters describing the principles of momentum transfer, heat transfer, and mass transfer in single phase and multiphase systems. Each chapter includes examples with solutions and exercises to facilitate students’ learning. Diagnostic problems are also provided at the end of each part to assess students’ comprehension of the material.  The book is aimed primarily at students in materials science and engineering. However, it can also serve as a useful reference text in chemical engineering as well as an introductory transport phenomena text in mechanical engineering. In addition, researchers and engineers engaged in materials processing operations will find the material use...

  5. Efficacy of an Online Resource for Teaching Interpersonal Problem Solving Skills to Women Graduate Students in Engineering

    Science.gov (United States)

    Bekki, Jennifer M.; Bernstein, Bianca; Fabert, Natalie; Gildar, Natalie; Way, Amy

    2014-01-01

    Interpersonal problem solving skills allow engineers to prevent interpersonal difficulties more effectively and to manage conflict, both of which are critical to successful participation on teams. This research provides evidence that the "Career"WISE online learning environment can improve those skills among women in engineering graduate…

  6. Applications of artificial intelligence in engineering problems

    Energy Technology Data Exchange (ETDEWEB)

    Sriram, D; Adey, R

    1986-01-01

    This book presents the papers given at a conference on the use of artificial intelligence in engineering. Topics considered at the conference included Prolog logic, expert systems, knowledge representation and acquisition, knowledge bases, machine learning, robotics, least-square algorithms, vision systems for robots, natural language, probability, mechanical engineering, civil engineering, and electrical engineering.

  7. Fluctuation theory of solutions applications in chemistry, chemical engineering, and biophysics

    CERN Document Server

    Smith, Paul E

    2013-01-01

    There are essentially two theories of solutions that can be considered exact: the McMillan-Mayer theory and Fluctuation Solution Theory (FST). The first is mostly limited to solutes at low concentrations, while FST has no such issue. It is an exact theory that can be applied to any stable solution regardless of the number of components and their concentrations, and the types of molecules and their sizes. Fluctuation Theory of Solutions: Applications in Chemistry, Chemical Engineering, and Biophysics outlines the general concepts and theoretical basis of FST and provides a range of applications

  8. Response to Contradiction: Conflict Resolution Strategies Used by Students in Solving Problems of Chemical Equilibrium.

    Science.gov (United States)

    Niaz, Mansoor

    2001-01-01

    Illustrates how a novel problem of chemical equilibrium based on a closely related sequence of items can facilitate students' conceptual understanding. Students were presented with a chemical reaction in equilibrium to which a reactant was added as an external effect. Three studies were conducted to assess alternative conceptions. (Author/SAH)

  9. Environmental engineering. 2. ed.

    International Nuclear Information System (INIS)

    Foerstner, U.

    1991-01-01

    This introductory textbook has been written in response to the demand for information on environmentally sound techniques and methods. On the basis of the knowledge taught in traditional engineering sciences, and referring to it, the author explains the specific problems encountered in the various environmental sectors, and reviews and discusses the technical solutions available or possible. In this process, there is, of course, opportunity or reason enough to refer to ecologic, economic, ethical or legal aspects, too. The book takes pollutants in a very general sense, their origin (sources), dispersion or transport, and their effects on the environment, as a red thread leading to the relevant technical equipment or engineering methods for problem solution in the various environmental sectors. An extensive and detailed bibliography points to literature for further reading. This second edition under review focusses on environmental problems in the eastern states of the Federal Republic: an account of the situation there refers to 'water' (catchment area of the Elbe river), 'soil' (long-standing pollution due to the mining industry in Thueringen and Sachsen), and 'air' (dispersion of pollutants, radon in uranium mines). The chapter 'Pollutants' now contains references to the handling of noxious chemical in accordance with the Ordinance on transport and handling of dangerous goods, explains the (mis)-development in the chlorine industry, shows the different dispersion processes of organic chemicals, etc. The chapters 'waste' and 'recycling' now part more emphasis on showing the significance of short- or medium-termed measures for prevention or rentilization of waste. (orig./HSCH) With 116 figs [de

  10. Environmental engineering. 3. ed.

    International Nuclear Information System (INIS)

    Foerstner, U.

    1992-01-01

    This introductory textbook has been written in response to the demand for information on environmentally sound techniques and methods. On the basis of the knowledge taught in traditional engineering sciences, and referring to it, the author explains the specific problems encountered in the various environmental sectors, and reviews and discusses the technical solutions available or possible. In this process, there is, of course, opportunity or reason enough to refer to ecologic, economic, ethical or legal aspects, too. The book takes pollutants in a very general sense, their origin (sources), dispersion or transport, and their effects on the environment, as a red thread leading to the relevant technical equipment or engineering methods for problem solution in the various environmental sectors. An extensive and detailed bibliography points to literature for further reading. This third edition under review focusses on environmental problems in the eastern states of the Federal Republic: an account of the situation there refers to 'water' (catchment area of the Elbe river), 'soil' (long-standing pollution due to the mining industry in Thueringen and Sachsen), and 'air' (dispersion of pollutants, radon in uranium mines). The chapter 'Pollutants' now contains references to the handling of noxious chemical in accordance with the Ordinance on transport and handling of dangerous goods, explains the (mis)-development in the chlorine industry, shows the different dispersion processes of organic chemicals, etc. The chapters 'waste' and 'recycling' now part more emphasis on showing the significance of short- or medium-termed measures for prevention or rentilization of waste. (orig.) With 116 figs [de

  11. An Introduction to Parallel Cluster Computing Using PVM for Computer Modeling and Simulation of Engineering Problems

    International Nuclear Information System (INIS)

    Spencer, VN

    2001-01-01

    An investigation has been conducted regarding the ability of clustered personal computers to improve the performance of executing software simulations for solving engineering problems. The power and utility of personal computers continues to grow exponentially through advances in computing capabilities such as newer microprocessors, advances in microchip technologies, electronic packaging, and cost effective gigabyte-size hard drive capacity. Many engineering problems require significant computing power. Therefore, the computation has to be done by high-performance computer systems that cost millions of dollars and need gigabytes of memory to complete the task. Alternately, it is feasible to provide adequate computing in the form of clustered personal computers. This method cuts the cost and size by linking (clustering) personal computers together across a network. Clusters also have the advantage that they can be used as stand-alone computers when they are not operating as a parallel computer. Parallel computing software to exploit clusters is available for computer operating systems like Unix, Windows NT, or Linux. This project concentrates on the use of Windows NT, and the Parallel Virtual Machine (PVM) system to solve an engineering dynamics problem in Fortran

  12. Recent chemical engineering requirements as the result of TMI on-site experience

    International Nuclear Information System (INIS)

    Brooksbank, R.E. Sr.

    1980-01-01

    From the experiences gained from the on-site experience at TMI, it is apparent that the role of chemical engineers should increase in order for the nuclear option to proceed in a safe and efficient fashion. It is also obvious that as the results of the reports investigating the causes and effects of the accident come to light and attempts to backfit system designs to prevent a recurrence are studied, more technical demands will be placed on the profession

  13. Metabolic Engineering for Substrate Co-utilization

    Science.gov (United States)

    Gawand, Pratish

    Production of biofuels and bio-based chemicals is being increasingly pursued by chemical industry to reduce its dependence on petroleum. Lignocellulosic biomass (LCB) is an abundant source of sugars that can be used for producing biofuels and bio-based chemicals using fermentation. Hydrolysis of LCB results in a mixture of sugars mainly composed of glucose and xylose. Fermentation of such a sugar mixture presents multiple technical challenges at industrial scale. Most industrial microorganisms utilize sugars in a sequential manner due to the regulatory phenomenon of carbon catabolite repression (CCR). Due to sequential utilization of sugars, the LCB-based fermentation processes suffer low productivities and complicated operation. Performance of fermentation processes can be improved by metabolic engineering of microorganisms to obtain superior characteristics such as high product yield. With increased computational power and availability of complete genomes of microorganisms, use of model-based metabolic engineering is now a common practice. The problem of sequential sugar utilization, however, is a regulatory problem, and metabolic models have never been used to solve such regulatory problems. The focus of this thesis is to use model-guided metabolic engineering to construct industrial strains capable of co-utilizing sugars. First, we develop a novel bilevel optimization algorithm SimUp, that uses metabolic models to identify reaction deletion strategies to force co-utilization of two sugars. We then use SimUp to identify reaction deletion strategies to force glucose-xylose co-utilization in Escherichia coli. To validate SimUp predictions, we construct three mutants with multiple gene knockouts and test them for glucose-xylose utilization characteristics. Two mutants, designated as LMSE2 and LMSE5, are shown to co-utilize glucose and xylose in agreement with SimUp predictions. To understand the molecular mechanism involved in glucose-xylose co-utilization of the

  14. Finding hidden chemistry in ancient egyptian artifacts: Pigment degradation taught in a chemical engineering course

    OpenAIRE

    Giménez Izquierdo, Francisco Javier

    2015-01-01

    The main objective of this work was to show the application of the study of ancient technology and science on teaching (and learning) chemistry in Chemical Engineering Undergraduate studies. Degradation patterns of pigments used in Ancient Egypt were incorporated in the syllabus of the course entitled

  15. Advances in metabolic engineering of yeast Saccharomyces cerevisiae for production of chemicals

    DEFF Research Database (Denmark)

    Borodina, Irina; Nielsen, Jens

    2014-01-01

    Yeast Saccharomyces cerevisiae is an important industrial host for production of enzymes, pharmaceutical and nutraceutical ingredients and recently also commodity chemicals and biofuels. Here, we review the advances in modeling and synthetic biology tools and how these tools can speed up the deve......Yeast Saccharomyces cerevisiae is an important industrial host for production of enzymes, pharmaceutical and nutraceutical ingredients and recently also commodity chemicals and biofuels. Here, we review the advances in modeling and synthetic biology tools and how these tools can speed up...... the development of yeast cell factories. We also present an overview of metabolic engineering strategies for developing yeast strains for production of polymer monomers: lactic, succinic, and cis,cis-muconic acids. S. cerevisiae has already firmly established itself as a cell factory in industrial biotechnology...

  16. Environmental Engineering and Sustainable Development

    OpenAIRE

    Said Salah Eldin Elnashaie

    2018-01-01

    Chemical Engineering is a very rich discipline and it is best classified using System Theory (ST) and utilized using the Integrated System Approach (ISA). Environmental Engineering (EE) is a subsystem of Chemical Engineering and also a subsystem of Sustainable Development (SD). In this paper both EE and SD are discussed from a Chemical Engineering point of view utilizing ST and ISA.

  17. Under pressure: evolutionary engineering of yeast strains for improved performance in fuels and chemicals production.

    Science.gov (United States)

    Mans, Robert; Daran, Jean-Marc G; Pronk, Jack T

    2018-04-01

    Evolutionary engineering, which uses laboratory evolution to select for industrially relevant traits, is a popular strategy in the development of high-performing yeast strains for industrial production of fuels and chemicals. By integrating whole-genome sequencing, bioinformatics, classical genetics and genome-editing techniques, evolutionary engineering has also become a powerful approach for identification and reverse engineering of molecular mechanisms that underlie industrially relevant traits. New techniques enable acceleration of in vivo mutation rates, both across yeast genomes and at specific loci. Recent studies indicate that phenotypic trade-offs, which are often observed after evolution under constant conditions, can be mitigated by using dynamic cultivation regimes. Advances in research on synthetic regulatory circuits offer exciting possibilities to extend the applicability of evolutionary engineering to products of yeasts whose synthesis requires a net input of cellular energy. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  18. Modeling and simulation of different and representative engineering problems using Network Simulation Method

    Science.gov (United States)

    2018-01-01

    Mathematical models simulating different and representative engineering problem, atomic dry friction, the moving front problems and elastic and solid mechanics are presented in the form of a set of non-linear, coupled or not coupled differential equations. For different parameters values that influence the solution, the problem is numerically solved by the network method, which provides all the variables of the problems. Although the model is extremely sensitive to the above parameters, no assumptions are considered as regards the linearization of the variables. The design of the models, which are run on standard electrical circuit simulation software, is explained in detail. The network model results are compared with common numerical methods or experimental data, published in the scientific literature, to show the reliability of the model. PMID:29518121

  19. Finding Hidden Chemistry in Ancient Egyptian Artifacts: Pigment Degradation Taught in a Chemical Engineering Course

    Science.gov (United States)

    Gime´nez, Javier

    2015-01-01

    The main objective of this work was to show the application of the study of ancient technology and science on teaching (and learning) chemistry in Chemical Engineering Undergraduate studies. Degradation patterns of pigments used in Ancient Egypt were incorporated in the syllabus of the course entitled "Technological and Scientific…

  20. Genome and metabolic engineering in non-conventional yeasts: Current advances and applications.

    Science.gov (United States)

    Löbs, Ann-Kathrin; Schwartz, Cory; Wheeldon, Ian

    2017-09-01

    Microbial production of chemicals and proteins from biomass-derived and waste sugar streams is a rapidly growing area of research and development. While the model yeast Saccharomyces cerevisia e is an excellent host for the conversion of glucose to ethanol, production of other chemicals from alternative substrates often requires extensive strain engineering. To avoid complex and intensive engineering of S. cerevisiae, other yeasts are often selected as hosts for bioprocessing based on their natural capacity to produce a desired product: for example, the efficient production and secretion of proteins, lipids, and primary metabolites that have value as commodity chemicals. Even when using yeasts with beneficial native phenotypes, metabolic engineering to increase yield, titer, and production rate is essential. The non-conventional yeasts Kluyveromyces lactis, K. marxianus, Scheffersomyces stipitis, Yarrowia lipolytica, Hansenula polymorpha and Pichia pastoris have been developed as eukaryotic hosts because of their desirable phenotypes, including thermotolerance, assimilation of diverse carbon sources, and high protein secretion. However, advanced metabolic engineering in these yeasts has been limited. This review outlines the challenges of using non-conventional yeasts for strain and pathway engineering, and discusses the developed solutions to these problems and the resulting applications in industrial biotechnology.

  1. [Insights into engineering of cellulosic ethanol].

    Science.gov (United States)

    Yue, Guojun; Wu, Guoqing; Lin, Xin

    2014-06-01

    For energy security, air pollution concerns, coupled with the desire to sustain the agricultural sector and revitalize the rural economy, many countries have applied ethanol as oxygenate or fuel to supplement or replace gasoline in transportation sector. Because of abundant feedstock resources and effective reduction of green-house-gas emissions, the cellulosic ethanol has attracted great attention. With a couple of pioneers beginning to produce this biofuel from biomass in commercial quantities around the world, it is necessary to solve engineering problems and complete the economic assessment in 2015-2016, gradually enter the commercialization stage. To avoid "competing for food with humans and competing for land with food", the 1st generation fuel ethanol will gradually transit to the 2nd generation cellulosic ethanol. Based on the overview of cellulosic ethanol industrialization from domestic and abroad in recent years, the main engineering application problems encountered in pretreatment, enzymes and enzymatic hydrolysis, pentose/hexose co-fermentation strains and processes, equipment were discussed from chemical engineering and biotechnology perspective. The development direction of cellulosic ethanol technology in China was addressed.

  2. Adapting Experiential Learning to Develop Problem-Solving Skills in Deaf and Hard-of-Hearing Engineering Students.

    Science.gov (United States)

    Marshall, Matthew M; Carrano, Andres L; Dannels, Wendy A

    2016-10-01

    Individuals who are deaf and hard-of-hearing (DHH) are underrepresented in science, technology, engineering, and mathematics (STEM) professions, and this may be due in part to their level of preparation in the development and retention of mathematical and problem-solving skills. An approach was developed that incorporates experiential learning and best practices of STEM instruction to give first-year DHH students enrolled in a postsecondary STEM program the opportunity to develop problem-solving skills in real-world scenarios. Using an industrial engineering laboratory that provides manufacturing and warehousing environments, students were immersed in real-world scenarios in which they worked on teams to address prescribed problems encountered during the activities. The highly structured, Plan-Do-Check-Act approach commonly used in industry was adapted for the DHH student participants to document and communicate the problem-solving steps. Students who experienced the intervention realized a 14.6% improvement in problem-solving proficiency compared with a control group, and this gain was retained at 6 and 12 months, post-intervention. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  3. Genetic engineering in biotechnology

    Energy Technology Data Exchange (ETDEWEB)

    Bedate, C.A.; Morales, J.C.; Lopez, E.H.

    1981-09-01

    The objective of this book is to encourage the use of genetic engineering for economic development. The report covers: (1) Precedents of genetic engineering; (2) a brief description of the technology, including the transfer of DNA in bacteria (vectors, E. coli and B. subtilis hosts, stages, and technical problems), practical examples of techniques used and their products (interferon; growth hormone; insulin; treatment of blood cells, Talasemia, and Lesch-Nyhan syndrome; and more nutritious soya), transfer to higher organisms, and cellular fusion; (3) biological risks and precautions; (4) possible applications (production of hydrogen, hydrocarbons, alcohol, chemicals, enzymes, peptides, viral antigens, monoclonal antibodies, genes, proteins, and insecticides; metal extraction; nitrogen fixation; biodegradation; and new varieties of plants and animals; and (5) international activities.

  4. Engineering Risk Assessment of Space Thruster Challenge Problem

    Science.gov (United States)

    Mathias, Donovan L.; Mattenberger, Christopher J.; Go, Susie

    2014-01-01

    The Engineering Risk Assessment (ERA) team at NASA Ames Research Center utilizes dynamic models with linked physics-of-failure analyses to produce quantitative risk assessments of space exploration missions. This paper applies the ERA approach to the baseline and extended versions of the PSAM Space Thruster Challenge Problem, which investigates mission risk for a deep space ion propulsion system with time-varying thruster requirements and operations schedules. The dynamic mission is modeled using a combination of discrete and continuous-time reliability elements within the commercially available GoldSim software. Loss-of-mission (LOM) probability results are generated via Monte Carlo sampling performed by the integrated model. Model convergence studies are presented to illustrate the sensitivity of integrated LOM results to the number of Monte Carlo trials. A deterministic risk model was also built for the three baseline and extended missions using the Ames Reliability Tool (ART), and results are compared to the simulation results to evaluate the relative importance of mission dynamics. The ART model did a reasonable job of matching the simulation models for the baseline case, while a hybrid approach using offline dynamic models was required for the extended missions. This study highlighted that state-of-the-art techniques can adequately adapt to a range of dynamic problems.

  5. Integrating Creativity Training into Problem and Project-Based Learning (PBL) Curriculum in Engineering Education

    DEFF Research Database (Denmark)

    Zhou, Chunfang

    2012-01-01

    In order to foster creative engineers, a creativity training programme was carried out in medialogy education in a Problem and Project-Based Learning (PBL) environment at Aalborg University, Denmark. This paper focuses on the question of how engineering students perceive the strategy of integrating...... creativity training into a PBL curriculum. A total of 20 medialogy students in the training programme were interviewed. The data shows that the training programme was thought useful and students get benefits such as gaining project work skills, creative concepts and confidence of being creative. However...

  6. Design considerations and challenges for mechanical stretch bioreactors in tissue engineering.

    Science.gov (United States)

    Lei, Ying; Ferdous, Zannatul

    2016-05-01

    With the increase in average life expectancy and growing aging population, lack of functional grafts for replacement surgeries has become a severe problem. Engineered tissues are a promising alternative to this problem because they can mimic the physiological function of the native tissues and be cultured on demand. Cyclic stretch is important for developing many engineered tissues such as hearts, heart valves, muscles, and bones. Thus a variety of stretch bioreactors and corresponding scaffolds have been designed and tested to study the underlying mechanism of tissue formation and to optimize the mechanical conditions applied to the engineered tissues. In this review, we look at various designs of stretch bioreactors and common scaffolds and offer insights for future improvements in tissue engineering applications. First, we summarize the requirements and common configuration of stretch bioreactors. Next, we present the features of different actuating and motion transforming systems and their applications. Since most bioreactors must measure detailed distributions of loads and deformations on engineered tissues, techniques with high accuracy, precision, and frequency have been developed. We also cover the key points in designing culture chambers, nutrition exchanging systems, and regimens used for specific tissues. Since scaffolds are essential for providing biophysical microenvironments for residing cells, we discuss materials and technologies used in fabricating scaffolds to mimic anisotropic native tissues, including decellularized tissues, hydrogels, biocompatible polymers, electrospinning, and 3D bioprinting techniques. Finally, we present the potential future directions for improving stretch bioreactors and scaffolds. © 2016 American Institute of Chemical Engineers Biotechnol. Prog., 32:543-553, 2016. © 2016 American Institute of Chemical Engineers.

  7. Engineering an Obligate Photoautotrophic Cyanobacterium to Utilize Glycerol for Growth and Chemical Production.

    Science.gov (United States)

    Kanno, Masahiro; Atsumi, Shota

    2017-01-20

    Cyanobacteria have attracted much attention as a means to directly recycle carbon dioxide into valuable chemicals that are currently produced from petroleum. However, the titers and productivities achieved are still far below the level required in industry. To make a more industrially applicable production scheme, glycerol, a byproduct of biodiesel production, can be used as an additional carbon source for photomixotrophic chemical production. Glycerol is an ideal candidate due to its availability and low cost. In this study, we found that a heterologous glycerol respiratory pathway enabled Synechococcus elongatus PCC 7942 to utilize extracellular glycerol. The engineered strain produced 761 mg/L of 2,3-butanediol in 48 h with a 290% increase over the control strain under continuous light conditions. Glycerol supplementation also allowed for continuous cell growth and 2,3-butanediol production in diurnal light conditions. These results highlight the potential of glycerol as an additional carbon source for photomixotrophic chemical production in cyanobacteria.

  8. Ionic liquids in chemical engineering.

    Science.gov (United States)

    Werner, Sebastian; Haumann, Marco; Wasserscheid, Peter

    2010-01-01

    The development of engineering applications with ionic liquids stretches back to the mid-1990s when the first examples of continuous catalytic processes using ionic liquids and the first studies of ionic liquid-based extractions were published. Ever since, the use of ionic liquids has seen tremendous progress in many fields of chemistry and engineering, and the first commercial applications have been reported. The main driver for ionic liquid engineering applications is to make practical use of their unique property profiles, which are the result of a complex interplay of coulombic, hydrogen bonding and van der Waals interactions. Remarkably, many ionic liquid properties can be tuned in a wide range by structural modifications at their cation and anion. This review highlights specific examples of ionic liquid applications in catalysis and in separation technologies. Additionally, the application of ionic liquids as working fluids in process machines is introduced.

  9. Governing Engineering

    DEFF Research Database (Denmark)

    Buch, Anders

    2012-01-01

    Most people agree that our world face daunting problems and, correctly or not, technological solutions are seen as an integral part of an overall solution. But what exactly are the problems and how does the engineering ‘mind set’ frame these problems? This chapter sets out to unravel dominant...... perspectives in challenge per-ception in engineering in the US and Denmark. Challenge perception and response strategies are closely linked through discursive practices. Challenge perceptions within the engineering community and the surrounding society are thus critical for the shaping of engineering education...... and the engineering profession. Through an analysis of influential reports and position papers on engineering and engineering education the chapter sets out to identify how engineering is problematized and eventually governed. Drawing on insights from governmentality studies the chapter strives to elicit the bodies...

  10. Governing Engineering

    DEFF Research Database (Denmark)

    Buch, Anders

    2011-01-01

    Abstract: Most people agree that our world faces daunting problems and, correctly or not, technological solutions are seen as an integral part of an overall solution. But what exactly are the problems and how does the engineering ‘mind set’ frame these problems? This chapter sets out to unravel...... dominant perspectives in challenge perception in engineering in the US and Denmark. Challenge perception and response strategies are closely linked through discursive practices. Challenge perceptions within the engineering community and the surrounding society are thus critical for the shaping...... of engineering education and the engineering profession. Through an analysis of influential reports and position papers on engineering and engineering education the chapter sets out to identify how engineering is problematized and eventually governed. Drawing on insights from governmentality studies the chapter...

  11. Determination of Gibbs energies of formation in aqueous solution using chemical engineering tools.

    Science.gov (United States)

    Toure, Oumar; Dussap, Claude-Gilles

    2016-08-01

    Standard Gibbs energies of formation are of primary importance in the field of biothermodynamics. In the absence of any directly measured values, thermodynamic calculations are required to determine the missing data. For several biochemical species, this study shows that the knowledge of the standard Gibbs energy of formation of the pure compounds (in the gaseous, solid or liquid states) enables to determine the corresponding standard Gibbs energies of formation in aqueous solutions. To do so, using chemical engineering tools (thermodynamic tables and a model enabling to predict activity coefficients, solvation Gibbs energies and pKa data), it becomes possible to determine the partial chemical potential of neutral and charged components in real metabolic conditions, even in concentrated mixtures. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Engineering-Based Problem Solving Strategies in AP Calculus: An Investigation into High School Student Performance on Related Rate Free-Response Problems

    Science.gov (United States)

    Thieken, John

    2012-01-01

    A sample of 127 high school Advanced Placement (AP) Calculus students from two schools was utilized to study the effects of an engineering design-based problem solving strategy on student performance with AP style Related Rate questions and changes in conceptions, beliefs, and influences. The research design followed a treatment-control multiple…

  13. Treatment of paraffin problems in petroleum production with chemicals; Tratamento de problemas parafinicos com agentes quimicos na producao de petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Jennings, David; Yin, Ralph; Weispfennig, Klaus; Newberry, Mike [Baker Petrolite, Sugar Land, TX (United States)

    2004-07-01

    Paraffin problems can greatly reduce production of certain crude oils, if correct methods to control the problems are not used. These problems are primarily related to flow line deposition and reduction in crude oil flow properties caused by wax network growth. Deep water production and production of high-wax content crude oils can be especially problematic. Much of the petroleum production in Brazil falls in these categories: in the Campos Basin and in Bahia. Paraffin problems can be controlled with diverse methods. These methods include use of: pigging, insulation, heating, and chemicals. Sometimes, the use of chemicals can be very practical, alone or in combination with other methods. This paper discusses the use of chemicals for the treatment of paraffin problems. Three types of treatments are discussed: prevention of deposition in flow lines with paraffin inhibitors; improvement in flow properties of crude oils with pour point depressants, and removal of paraffin deposits with dispersants. The discussion includes the physical effects of the treatment chemicals and field examples. (author)

  14. Bio-based targeted chemical engineering education : Role and impact of bio-based energy and resourcedevelopment projects

    NARCIS (Netherlands)

    N.M. Márquez Luzardoa; Dr. ir. Jan Venselaar

    2012-01-01

    Avans University of Applied Sciences is redrafting its courses and curricula in view of sustainability. For chemical engineering in particular that implies a focus on 'green' and bio-based processes, products and energy. Avans is situated in the Southwest region of the Netherlands and specifically

  15. Load-Dependent Emission Factors and Chemical Characteristics of IVOCs from a Medium-Duty Diesel Engine.

    Science.gov (United States)

    Cross, Eben S; Sappok, Alexander G; Wong, Victor W; Kroll, Jesse H

    2015-11-17

    A detailed understanding of the climate and air quality impacts of mobile-source emissions requires the characterization of intermediate-volatility organic compounds (IVOCs), relatively-low-vapor-pressure gas-phase species that may generate secondary organic aerosol with high yields. Due to challenges associated with IVOC detection and quantification, IVOC emissions remain poorly understood at present. Here, we describe measurements of the magnitude and composition of IVOC emissions from a medium-duty diesel engine. Measurements are made on an engine dynamometer and utilize a new mass-spectrometric instrument to characterize the load dependence of the emissions in near-real-time. Results from steady-state engine operation indicate that IVOC emissions are highly dependent on engine power, with highest emissions at engine idle and low-load operation (≤25% maximum rated power) with a chemical composition dominated by saturated hydrocarbon species. Results suggest that unburned fuel components are the dominant IVOCs emitted at low loads. As engine load increases, IVOC emissions decline rapidly and become increasingly characterized by unsaturated hydrocarbons and oxygenated organics, newly formed from incomplete combustion processes at elevated engine temperatures and pressures. Engine transients, including a cold-start ignition and engine acceleration, show IVOC emission profiles that are different in amount or composition compared to steady-state combustion, underscoring the utility of characterizing IVOC emissions with high time resolution across realistic engine operating conditions. We find possible evidence for IVOC losses on unheated dilution and sampling surfaces, which need to be carefully accounted for in IVOC emission studies.

  16. Advances in metabolic pathway and strain engineering paving the way for sustainable production of chemical building blocks.

    Science.gov (United States)

    Chen, Yun; Nielsen, Jens

    2013-12-01

    Bio-based production of chemical building blocks from renewable resources is an attractive alternative to petroleum-based platform chemicals. Metabolic pathway and strain engineering is the key element in constructing robust microbial chemical factories within the constraints of cost effective production. Here we discuss how the development of computational algorithms, novel modules and methods, omics-based techniques combined with modeling refinement are enabling reduction in development time and thus advance the field of industrial biotechnology. We further discuss how recent technological developments contribute to the development of novel cell factories for the production of the building block chemicals: adipic acid, succinic acid and 3-hydroxypropionic acid. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Environmental Management Plan for the Chemical Engineering Laboratory (LIQ) of the National University of Colombia, Bogotá

    OpenAIRE

    Javier Gama Chávez; Martha Lozano García; Paulo César Narváez Rincón; Óscar Javier Suárez Medina

    2004-01-01

    An Enviromental Management Plan was formulated with the objective of improving the environmental performance of the Chemical Engineering Laboratory (LIQ). The plan was supported on the principles established by the ISO 140001 standard. In a first step, an environmental politic was proposed. Next, by means of an initial review of the laboratory, the most significant impacts related to the activities developed in the Laboratory were identified: dangerous chemical wastes accumulation, water cont...

  18. 3-D simulation of soot formation in a direct-injection diesel engine based on a comprehensive chemical mechanism and method of moments

    Science.gov (United States)

    Zhong, Bei-Jing; Dang, Shuai; Song, Ya-Na; Gong, Jing-Song

    2012-02-01

    Here, we propose both a comprehensive chemical mechanism and a reduced mechanism for a three-dimensional combustion simulation, describing the formation of polycyclic aromatic hydrocarbons (PAHs), in a direct-injection diesel engine. A soot model based on the reduced mechanism and a method of moments is also presented. The turbulent diffusion flame and PAH formation in the diesel engine were modelled using the reduced mechanism based on the detailed mechanism using a fixed wall temperature as a boundary condition. The spatial distribution of PAH concentrations and the characteristic parameters for soot formation in the engine cylinder were obtained by coupling a detailed chemical kinetic model with the three-dimensional computational fluid dynamic (CFD) model. Comparison of the simulated results with limited experimental data shows that the chemical mechanisms and soot model are realistic and correctly describe the basic physics of diesel combustion but require further development to improve their accuracy.

  19. Thermodynamics an advanced textbook for chemical engineers

    CERN Document Server

    Astarita, Gianni

    1989-01-01

    If a Writer would know how to behave himself with relation to Posterity; let him consider in old Books, what he finds, that he is glad to know; and what Omissions he most laments. Jonathan Swift This book emerges from a long story of teaching. I taught chemical engineering thermodynamics for about ten years at the University of Naples in the 1960s, and I still remember the awkwardness that I felt about any textbook I chose to consider-all of them seemed to be vague at best, and the standard of logical rigor seemed immensely inferior to what I could find in books on such other of the students in my first class subjects as calculus and fluid mechanics. One (who is now Prof. F. Gioia of the University of Naples) once asked me a question which I have used here as Example 4. 2-more than 20 years have gone by, and I am still waiting for a more intelligent question from one of my students. At the time, that question compelled me to answer in a way I didn't like, namely "I'll think about it, and I hope I'll have the ...

  20. Implementing a Systematic Process for Rapidly Embedding Sustainability within Chemical Engineering Education: A Case Study of James Cook University, Australia

    Science.gov (United States)

    Sheehan, Madoc; Schneider, Phil; Desha, Cheryl

    2012-01-01

    Sustainability has emerged as a primary context for engineering education in the 21st Century, particularly the sub-discipline of chemical engineering. However, there is confusion over how to go about integrating sustainability knowledge and skills systemically within bachelor degrees. This paper addresses this challenge, using a case study of an…

  1. Nanostructure Engineered Chemical Sensors for Hazardous Gas and Vapor Detection

    Science.gov (United States)

    Li, Jing; Lu, Yijiang

    2005-01-01

    A nanosensor technology has been developed using nanostructures, such as single walled carbon nanotubes (SWNTs) and metal oxides nanowires or nanobelts, on a pair of interdigitated electrodes (IDE) processed with a silicon based microfabrication and micromachining technique. The IDE fingers were fabricated using thin film metallization techniques. Both in-situ growth of nanostructure materials and casting of the nanostructure dispersions were used to make chemical sensing devices. These sensors have been exposed to hazardous gases and vapors, such as acetone, benzene, chlorine, and ammonia in the concentration range of ppm to ppb at room temperature. The electronic molecular sensing in our sensor platform can be understood by electron modulation between the nanostructure engineered device and gas molecules. As a result of the electron modulation, the conductance of nanodevice will change. Due to the large surface area, low surface energy barrier and high thermal and mechanical stability, nanostructured chemical sensors potentially can offer higher sensitivity, lower power consumption and better robustness than the state-of-the-art systems, which make them more attractive for defense and space applications. Combined with MEMS technology, light weight and compact size sensors can be made in wafer scale with low cost.

  2. Role of the chemical engineering technician in applied research related to tritium separation from aqueous effluents

    International Nuclear Information System (INIS)

    Nelson, S.D.

    1978-01-01

    Applied research and development activities related to the removal of tritium from aqueous effluent streams have presented broad opportunities to the chemical engineering technician for professional growth. Technician job activities involve operating complex analytical instrumentation and constructing, maintaining, and operating experimental electrolysis apparatus. The technician is a member of a professional team including scientific, engineering, and other technical personnel and as such is expected to exercise creative thought. Proximity of a large university and availability of formalized ''in house'' training courses provide incentives for technicians to broaden their academic base concurrent with their work involvement

  3. Process engineering versus product engineering - A case study on volatile organic compounds removal

    DEFF Research Database (Denmark)

    Coutinho, João A.P.; Vilela, T.; Pereira, P.

    2005-01-01

    Three solutions for removing the dangerous volatile organic compound (VOC) xylene from an industrial coating process are presented and compared. Two of them are based on classical process engineering principles, i.e., development of separation-cleaning methods such as incineration and adsorption...... to the problem-need specified in the beginning of the project, but producing a novel formulation (chemical product design) represents a method that results to a completely xylene-free process which is environmentally and economically more interesting than those generated via the more traditional process...

  4. Operation of chemical incinerator for disposal of legacy chemicals

    International Nuclear Information System (INIS)

    Singhal, R.K.; Basu, H.; Saha, S.; Pimple, M.V.; Naik, P.D.

    2017-01-01

    For safe disposal of age-old legacy and unused chemicals in BARC, Trombay, oil-fired chemical incinerator with a capacity of 20 kg h"-"1 for solid and liquid chemical is installed adjacent to trash incinerator near RSMS, Gamma Field. The Incinerator was supplied by M/s B. L. Engineering Works, Ahmedabad. Commission of the same at Trombay site was carried out, under the supervision of Civil Engineering (CED), Technical Services Division (TSD) and Analytical Chemistry Division (custodian of the facility)

  5. Scaffold of chitosan/poly(vinyl alcohol) blend chemically crosslinked by glutaraldehyde for tissue engineering applications

    International Nuclear Information System (INIS)

    Costa Junior, Ezequiel de S.; Laguardia-Nascimento, Mateus; Barbosa-Stancioli, Edel F.; Mansur, Herman S.

    2009-01-01

    Chitosan/PVA based films were chemically crosslinked by glutaraldehyde (GA) in order to achieve scaffolds for potential tissue engineering application. Both precursors and developed films were characterized by FTIR and XRD in order to determine the presence of chemicals groups and nanostructural order, respectively. The results have showed that the GA crosslinking have altered the crystallinity of the chitosan and the increase on the C=N bands and decreasing of NH 2 bands suggest that Chitosan/GA crosslinking has preference to occur in the carbon 2 by Schiff's base. The mechanical properties, swelling behavior, degradation rate in vitro and cellular viability were compatible with the characteristic of an epithelial tissue. The material presented a toughness range from 1.4 to 34MJ/m3, swelling from 150% to 700% in 24h, degradation rate from 20% to 75% (wt%) in 24h and cellular viability in vitro above 60% compared to the cellular control. The developed scaffolds from the films have also showed swelling and degradation in vitro properties well-matched for biomedical applications in tissue engineering (author)

  6. Petroleum Diesel Fuel and Linseed Oil Mixtures as Engine Fuels

    Science.gov (United States)

    Markov, V. A.; Kamaltdinov, V. G.; Savastenko, A. A.

    2018-01-01

    The actual problem is the use of alternative biofuels in automotive diesel engines. Insufficiently studied are the indicators of toxicity of exhaust gases of these engines operating on biofuel. The aim of the study is to identify indicators of the toxicity of exhaust gases when using of petroleum diesel fuel and linseed oil mixtures as a fuel for automotive diesel engines. Physical and chemical properties of linseed oil and its mixtures with petroleum diesel fuel are considered. Experimental researches of D-245.12C diesel are carried out on mixtures of diesel fuel and corn oil with a different composition. An opportunity of exhaust toxicity indexes improvement using these mixtures as a fuel for automobiles engine is shown.

  7. Change, exchange, and rearrange: protein engineering for the biotechnological production of fuels, pharmaceuticals, and other chemicals.

    Science.gov (United States)

    Fisher, Michael A; Tullman-Ercek, Danielle

    2013-12-01

    Enzymes are indispensable in the effort to produce chemicals from fuels to pharmaceuticals in an ecologically friendly manner. They have the potential to catalyze reactions with high specificity and efficiency without the use of hazardous chemicals. Nature provides an extensive collection of enzymes, but often these must be altered to perform desired functions under required conditions. Advances in protein engineering permit the design and/or directed evolution of enzymes specifically tailored for such industrial applications. Recent years have seen the development of improved enzymes to assist in both the conversion of biomass into fuels and chemicals, and the creation of key intermediates in pharmaceutical production. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. A review of engineering aspects of intensification of chemical synthesis using ultrasound.

    Science.gov (United States)

    Sancheti, Sonam V; Gogate, Parag R

    2017-05-01

    Cavitation generated using ultrasound can enhance the rates of several chemical reactions giving better selectivity based on the physical and chemical effects. The present review focuses on overview of the different reactions that can be intensified using ultrasound followed by the discussion on the chemical kinetics for ultrasound assisted reactions, engineering aspects related to reactor designs and effect of operating parameters on the degree of intensification obtained for chemical synthesis. The cavitational effects in terms of magnitudes of collapse temperatures and collapse pressure, number of free radicals generated and extent of turbulence are strongly dependent on the operating parameters such as ultrasonic power, frequency, duty cycle, temperature as well as physicochemical parameters of liquid medium which controls the inception of cavitation. Guidelines have been presented for the optimum selection based on the critical analysis of the existing literature so that maximum process intensification benefits can be obtained. Different reactor designs have also been analyzed with guidelines for efficient scale up of the sonochemical reactor, which would be dependent on the type of reaction, controlling mechanism of reaction, catalyst and activation energy requirements. Overall, it has been established that sonochemistry offers considerable potential for green and sustainable processing and efficient scale up procedures are required so as to harness the effects at actual commercial level. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. The Effect on Pupils' Science Performance and Problem-Solving Ability through Lego: An Engineering Design-Based Modeling Approach

    Science.gov (United States)

    Li, Yanyan; Huang, Zhinan; Jiang, Menglu; Chang, Ting-Wen

    2016-01-01

    Incorporating scientific fundamentals via engineering through a design-based methodology has proven to be highly effective for STEM education. Engineering design can be instantiated for learning as they involve mental and physical stimulation and develop practical skills especially in solving problems. Lego bricks, as a set of toys based on design…

  10. A Matter of Chemical Engineering (On Teaching an Intensive Course in Technical Communication for Undergraduates).

    Science.gov (United States)

    Sullivan, Ralda M.

    Because the ability to write reports and make oral presentations is crucial to success, the Department of Chemical Engineering at the University of California (Berkeley) has set up an in-house, required course that is given every semester to about 60 students. Divided into three sections, one of which is for non-native speakers of English, the…

  11. Designing Solutions by a Student Centred Approach: Integration of Chemical Process Simulation with Statistical Tools to Improve Distillation Systems

    Directory of Open Access Journals (Sweden)

    Isabel M. Joao

    2017-09-01

    Full Text Available Projects thematically focused on simulation and statistical techniques for designing and optimizing chemical processes can be helpful in chemical engineering education in order to meet the needs of engineers. We argue for the relevance of the projects to improve a student centred approach and boost higher order thinking skills. This paper addresses the use of Aspen HYSYS by Portuguese chemical engineering master students to model distillation systems together with statistical experimental design techniques in order to optimize the systems highlighting the value of applying problem specific knowledge, simulation tools and sound statistical techniques. The paper summarizes the work developed by the students in order to model steady-state processes, dynamic processes and optimize the distillation systems emphasizing the benefits of the simulation tools and statistical techniques in helping the students learn how to learn. Students strengthened their domain specific knowledge and became motivated to rethink and improve chemical processes in their future chemical engineering profession. We discuss the main advantages of the methodology from the students’ and teachers perspective

  12. Solving bi-level optimization problems in engineering design using kriging models

    Science.gov (United States)

    Xia, Yi; Liu, Xiaojie; Du, Gang

    2018-05-01

    Stackelberg game-theoretic approaches are applied extensively in engineering design to handle distributed collaboration decisions. Bi-level genetic algorithms (BLGAs) and response surfaces have been used to solve the corresponding bi-level programming models. However, the computational costs for BLGAs often increase rapidly with the complexity of lower-level programs, and optimal solution functions sometimes cannot be approximated by response surfaces. This article proposes a new method, namely the optimal solution function approximation by kriging model (OSFAKM), in which kriging models are used to approximate the optimal solution functions. A detailed example demonstrates that OSFAKM can obtain better solutions than BLGAs and response surface-based methods, and at the same time reduce the workload of computation remarkably. Five benchmark problems and a case study of the optimal design of a thin-walled pressure vessel are also presented to illustrate the feasibility and potential of the proposed method for bi-level optimization in engineering design.

  13. FORMULATION OF MATHEMATICAL PROBLEM DESCRIBING PHYSICAL AND CHEMICAL PROCESSES AT CONCRETE CORROSION

    Directory of Open Access Journals (Sweden)

    Sergey V. Fedosov

    2017-06-01

    Full Text Available The article deals with the relevance of new scientific research focused on modeling of physical and chemical processes occurring in the cement concrete at their exploitation. The basic types of concrete corrosion are described. The problem of mass transfer processes in a flat reinforced concrete wall at concrete corrosion of the first and the second types has been mathematically formulated.

  14. MATLAB as a tool as Analysis and Problem Solving Competency Development in Chemical Engineering Degree using MATLAB

    Directory of Open Access Journals (Sweden)

    Maria-Fernanda López-Pérez

    2016-10-01

    The principal purpose of this work is the students improvement using, as has been mentioned previously, MATLAB in a problem-based learning methodology. This methodology allows a more effective coordination in the degree. The present paper presents a real- world problem and the common elements of most problem-solving contexts and how is designed to function across all disciplines.

  15. Chemical and Enzymatic Strategies for Bacterial and Mammalian Cell Surface Engineering.

    Science.gov (United States)

    Bi, Xiaobao; Yin, Juan; Chen Guanbang, Ashley; Liu, Chuan-Fa

    2018-06-07

    The cell surface serves important functions such as the regulation of cell-cell and cell-environment interactions. The understanding and manipulation of the cell surface is important for a wide range of fundamental studies of cellular behavior and for biotechnological and medical applications. With the rapid advance of biology, chemistry and materials science, many strategies have been developed for the functionalization of bacterial and mammalian cell surfaces. Here, we review the recent development of chemical and enzymatic approaches to cell surface engineering with particular emphasis on discussing the advantages and limitations of each of these strategies. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. THE TRAVELLING SALESMAN PROBLEM IN THE ENGINEERING EDUCATION PROGRAMMING CURRICULUM

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    Yevgeny Gayev

    2017-11-01

    Full Text Available Objective: To make students familiar with the famous Traveling Salesman Problem (TSP and suggest the latter to become a common exercise in engineering programming curriculum provided the students master computer science in the easy programming environment MATLAB. Methods: easy programming in MATLAB makes true such modern educational approach as “discovery based” methodology. Results: a MATLAB TSP-program oriented to Ukrainian map is suggested that allows to pictorially demonstrate the process of optimal route search with an option to decelerate or accelerate the demonstration. The program is guessed to be useful both for learning the TSP as one of fundamental logistics problems and as an intriguing programming curriculum excersize. Several sub-programs according to key stone Computer Science Curriculum have also been suggested. This lies in line with recent “discovery based” learning methodology. Discussion: we explain how to create this program for visual discrete optimization, suggest required subprograms belonging to key stone programming algorithms including rather modern graphical user interface (GUI, how to use this MATLAB TSP-program for demonstration the drastical grows of solution time required. Conclusions: easy programming being realized in MATLAB makes dificult curriculum problems attractive to students; it focuses them to main problem’ features, laws and algorithms implementing the “discovery based” methodology in such a way.

  17. Genome and metabolic engineering in non-conventional yeasts: Current advances and applications

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    Ann-Kathrin Löbs

    2017-09-01

    Full Text Available Microbial production of chemicals and proteins from biomass-derived and waste sugar streams is a rapidly growing area of research and development. While the model yeast Saccharomyces cerevisiae is an excellent host for the conversion of glucose to ethanol, production of other chemicals from alternative substrates often requires extensive strain engineering. To avoid complex and intensive engineering of S. cerevisiae, other yeasts are often selected as hosts for bioprocessing based on their natural capacity to produce a desired product: for example, the efficient production and secretion of proteins, lipids, and primary metabolites that have value as commodity chemicals. Even when using yeasts with beneficial native phenotypes, metabolic engineering to increase yield, titer, and production rate is essential. The non-conventional yeasts Kluyveromyces lactis, K. marxianus, Scheffersomyces stipitis, Yarrowia lipolytica, Hansenula polymorpha and Pichia pastoris have been developed as eukaryotic hosts because of their desirable phenotypes, including thermotolerance, assimilation of diverse carbon sources, and high protein secretion. However, advanced metabolic engineering in these yeasts has been limited. This review outlines the challenges of using non-conventional yeasts for strain and pathway engineering, and discusses the developed solutions to these problems and the resulting applications in industrial biotechnology.

  18. Wildland fire management. Volume 1: Prevention methods and analysis. [systems engineering approach to California fire problems

    Science.gov (United States)

    Weissenberger, S. (Editor)

    1973-01-01

    A systems engineering approach is reported for the problem of reducing the number and severity of California's wildlife fires. Prevention methodologies are reviewed and cost benefit models are developed for making preignition decisions.

  19. System sight at a problem of efficiency of enterprises’s operaton of the Russian chemical complex

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    Svyatoslav Arkadyevich Nikitin

    2011-06-01

    Full Text Available Chemical industry plays an important role in the development of the domestic economy as one of the basic facilities of Russia's economy, laying the foundation for its long-term and stable development. As a major supplier of raw materials, intermediates, and products of various materials (plastics, chemical fibers, tires, paints and varnishes, dyes, fertilizers, feed additives, pharmaceuticals, medical equipment etc. in almost all sectors of industry, agriculture, health care, human services, commerce, science, culture and education, defense industry, chemical complex has direct impact on the efficiency of their operation and development in these new directions. Therefore, the condition and development of domestic chemistry determines the level of national competitiveness, economic growth and Russia's wealth. However, like most industries in Russia today, chemical industry is going through a difficult period. The presence of a set of common economic problems (identified by technological backwardness and high depreciation, low innovation activity of domestic enterprises of the chemical complex, a lack of effectiveness of the investment process, infrastructure and resource constraints etc., as well as internal management problems causes the rapid growth of interest of uncompetitive Russian chemical products on the world market. Under these conditions, not only a radical adjustment of the internal control systems and chemical plants, but also a significant organizational and economic change is required. Thus, unless we take measures to improve the domestic chemical industry in the coming years, almost all of it grow back and may get into the situation of struggle for survival.

  20. Systematic Approach to Calculate the Concentration of Chemical Species in Multi-Equilibrium Problems

    Science.gov (United States)

    Baeza-Baeza, Juan Jose; Garcia-Alvarez-Coque, Maria Celia

    2011-01-01

    A general systematic approach is proposed for the numerical calculation of multi-equilibrium problems. The approach involves several steps: (i) the establishment of balances involving the chemical species in solution (e.g., mass balances, charge balance, and stoichiometric balance for the reaction products), (ii) the selection of the unknowns (the…