WorldWideScience

Sample records for chatter cell-cell communication

  1. Engineered cell-cell communication via DNA messaging

    Directory of Open Access Journals (Sweden)

    Ortiz Monica E

    2012-09-01

    Full Text Available Abstract Background Evolution has selected for organisms that benefit from genetically encoded cell-cell communication. Engineers have begun to repurpose elements of natural communication systems to realize programmed pattern formation and coordinate other population-level behaviors. However, existing engineered systems rely on system-specific small molecules to send molecular messages among cells. Thus, the information transmission capacity of current engineered biological communication systems is physically limited by specific biomolecules that are capable of sending only a single message, typically “regulate transcription.” Results We have engineered a cell-cell communication platform using bacteriophage M13 gene products to autonomously package and deliver heterologous DNA messages of varying lengths and encoded functions. We demonstrate the decoupling of messages from a common communication channel via the autonomous transmission of various arbitrary genetic messages. Further, we increase the range of engineered DNA messaging across semisolid media by linking message transmission or receipt to active cellular chemotaxis. Conclusions We demonstrate decoupling of a communication channel from message transmission within engineered biological systems via the autonomous targeted transduction of user-specified heterologous DNA messages. We also demonstrate that bacteriophage M13 particle production and message transduction occurs among chemotactic bacteria. We use chemotaxis to improve the range of DNA messaging, increasing both transmission distance and communication bit rates relative to existing small molecule-based communication systems. We postulate that integration of different engineered cell-cell communication platforms will allow for more complex spatial programming of dynamic cellular consortia.

  2. Chatter and machine tools

    CERN Document Server

    Stone, Brian

    2014-01-01

    Focussing on occurrences of unstable vibrations, or Chatter, in machine tools, this book gives important insights into how to eliminate chatter with associated improvements in product quality, surface finish and tool wear. Covering a wide range of machining processes, including turning, drilling, milling and grinding, the author uses his research expertise and practical knowledge of vibration problems to provide solutions supported by experimental evidence of their effectiveness. In addition, this book contains links to supplementary animation programs that help readers to visualise the ideas detailed in the text. Advancing knowledge in chatter avoidance and suggesting areas for new innovations, Chatter and Machine Tools serves as a handbook for those desiring to achieve significant reductions in noise, longer tool and grinding wheel life and improved product finish.

  3. Working together for the common good: cell-cell communication in bacteria.

    Science.gov (United States)

    Stevens, Ann M; Schuster, Martin; Rumbaugh, Kendra P

    2012-05-01

    The 4th ASM Conference on Cell-Cell Communication in Bacteria was held in Miami, FL, from 6 to 9 November 2011. This review highlights three key themes that emerged from the many exciting talks and poster presentations in the area of quorum sensing: sociomicrobiology, signal transduction mechanisms, and interspecies communication.

  4. Cell-cell communication in the kidney microcirculation

    DEFF Research Database (Denmark)

    Sørensen, Charlotte Mehlin; von Holstein-Rathlou, Niels-Henrik

    2012-01-01

    the postglomerular vasculature. Cxs form gap junctions between neighboring cells, and as in other organ systems, the major function of Cxs in the kidney appears to be mediation of intercellular communication. Cxs may also form hemichannels that allow cellular secretion of signaling molecules like ATP, and thereby...... mediate paracrine signaling. Renal Cxs facilitate vascular conduction, juxtaglomerlar apparatus calcium signaling, and enable ECs and VSMCs to communicate. Thus, current research suggests multiple roles for Cxs in important regulatory mechanisms within the kidney, including the renin-angiotensin system...

  5. Validating a Conceptual Framework for the Core Concept of "Cell-Cell Communication"

    Science.gov (United States)

    Michael, Joel; Martinkova, Patricia; McFarland, Jenny; Wright, Ann; Cliff, William; Modell, Harold; Wenderoth, Mary Pat

    2017-01-01

    We have created and validated a conceptual framework for the core physiology concept of "cell-cell communication." The conceptual framework is composed of 51 items arranged in a hierarchy that is, in some instances, four levels deep. We have validated it with input from faculty who teach at a wide variety of institutional types. All…

  6. Analysis of Chatter Stability in Facing

    Science.gov (United States)

    Kebdani, S.; Sahli, A.; Rahmani, O.; Boutchicha, D.; Belarbi, A.

    This study attempts to develop a chatter model for predicting chatter stability conditions in hard turning. A linear model is developed by introducing non-uniform load distribution on a tool tip to account for the flank wear effect. Stability analysis based on the root locus method and the harmonic balance method is conducted to determine a critical stability parameter. To validate the model, a series of experiment is carried out to determine the stability limits as well as certain characteristic parameters for facing and straight turning. Chatter in hard turning has the feature that the critical stability limits increase very rapidly when the cutting speed is higher than 13 rev sec-1 for all feed directions. The main contributions of the study are threefold. First, chatter-free cutting conditions are predicted and can be used as a guideline for designing tools and machines. Second, the characteristics of chatter in hard turning, which is observed for the first time, helps to broaden our physical understanding of the interactions between the tool and the workpiece in hard turning. Third, experimental stability limits for different flank wear can contribute to lead more reasonable ways to consider the flank wear effect in chatter models of hard turning. Based on these contributions, the proposed linear chatter model will support to improve the productivity in many manufacturing processes. In addition, the chatter experimental data will be useful to develop other chatter models in hard turning.

  7. Exosome-Based Cell-Cell Communication in the Tumor Microenvironment

    Directory of Open Access Journals (Sweden)

    Joana Maia

    2018-02-01

    Full Text Available Tumors are not isolated entities, but complex systemic networks involving cell-cell communication between transformed and non-transformed cells. The milieu created by tumor-associated cells may either support or halt tumor progression. In addition to cell-cell contact, cells communicate through secreted factors via a highly complex system involving characteristics such as ligand concentration, receptor expression and integration of diverse signaling pathways. Of these, extracellular vesicles, such as exosomes, are emerging as novel cell-cell communication mediators in physiological and pathological scenarios. Exosomes, membrane vesicles of endocytic origin released by all cells (both healthy and diseased, ranging in size from 30 to 150 nm, transport all the main biomolecules, including lipids, proteins, DNAs, messenger RNAs and microRNA, and perform intercellular transfer of components, locally and systemically. By acting not only in tumor cells, but also in tumor-associated cells such as fibroblasts, endothelium, leukocytes and progenitor cells, tumor- and non-tumor cells-derived exosomes have emerged as new players in tumor growth and invasion, tumor-associated angiogenesis, tissue inflammation and immunologic remodeling. In addition, due to their property of carrying molecules from their cell of origin to the peripheral circulation, exosomes have been increasingly studied as sources of tumor biomarkers in liquid biopsies. Here we review the current literature on the participation of exosomes in the communication between tumor and tumor-associated cells, highlighting the role of this process in the setup of tumor microenvironments that modulate tumor initiation and metastasis.

  8. Bacterial cell-cell communication in the host via RRNPP peptide-binding regulators

    Directory of Open Access Journals (Sweden)

    David ePerez-Pascual

    2016-05-01

    Full Text Available Human microbiomes are composed of complex and dense bacterial consortia. In these environments, bacteria are able to react quickly to change by coordinating their gene expression at the population level via small signaling molecules. In Gram-positive bacteria, cell-cell communication is mostly mediated by peptides that are released into the extracellular environment. Cell-cell communication based on these peptides is especially widespread in the group Firmicutes, in which they regulate a wide array of biological processes, including functions related to host-microbe interactions. Among the different agents of communication, the RRNPP family of cytoplasmic transcriptional regulators, together with their cognate re-internalized signaling peptides, represents a group of emerging importance. RRNPP members that have been studied so far are found mainly in species of bacilli, streptococci, and enterococci. These bacteria are characterized as both human commensal and pathogenic, and share different niches in the human body with other microorganisms. The goal of this mini-review is to present the current state of research on the biological relevance of RRNPP mechanisms in the context of the host, highlighting their specific roles in commensalism or virulence.

  9. Vectorial signalling mechanism required for cell-cell communication during sporulation in Bacillus subtilis.

    Science.gov (United States)

    Diez, Veronica; Schujman, Gustavo E; Gueiros-Filho, Frederico J; de Mendoza, Diego

    2012-01-01

    Spore formation in Bacillus subtilis takes place in a sporangium consisting of two chambers, the forespore and the mother cell, which are linked by pathways of cell-cell communication. One pathway, which couples the proteolytic activation of the mother cell transcription factor σ(E) to the action of a forespore synthesized signal molecule, SpoIIR, has remained enigmatic. Signalling by SpoIIR requires the protein to be exported to the intermembrane space between forespore and mother cell, where it will interact with and activate the integral membrane protease SpoIIGA. Here we show that SpoIIR signal activity as well as the cleavage of its N-terminal extension is strictly dependent on the prespore fatty acid biosynthetic machinery. We also report that a conserved threonine residue (T27) in SpoIIR is required for processing, suggesting that signalling of SpoIIR is dependent on fatty acid synthesis probably because of acylation of T27. In addition, SpoIIR localization in the forespore septal membrane depends on the presence of SpoIIGA. The orchestration of σ(E) activation in the intercellular space by an acylated signal protein provides a new paradigm to ensure local transmission of a weak signal across the bilayer to control cell-cell communication during development. © 2011 Blackwell Publishing Ltd.

  10. Telecom Modeling with ChatterBell.

    Energy Technology Data Exchange (ETDEWEB)

    Jrad, Ahmad M.; Kelic, Andjelka

    2017-12-01

    This document provides a description and user manual for the ChatterBell voice telecom modeling and simulation capability. The intended audience consists of network planners and practitioners who wish to use the tool to model a particular voice network and analyze its behavior under varying assumptions and possible failure conditions. ChatterBell is built on top of the N-SMART voice simulation and visualization suite that was developed through collaboration between Sandia National Laboratories and Bell Laboratories of Lucent Technologies. The new and improved modeling and simulation tool has been modified and modernized to incorporate the latest development in the telecom world including the widespread use of VoIP technology. In addition, ChatterBell provides new commands and modeling capabilities that were not available in the N-SMART application.

  11. Cysteine-rich peptides (CRPs) mediate diverse aspects of cell-cell communication in plant reproduction and development.

    Science.gov (United States)

    Marshall, Eleanor; Costa, Liliana M; Gutierrez-Marcos, Jose

    2011-03-01

    Cell-cell communication in plants is essential for the correct co-ordination of reproduction, growth, and development. Studies to dissect this mode of communication have previously focussed primarily on the action of plant hormones as mediators of intercellular signalling. In animals, peptide signalling is a well-documented intercellular communication system, however, relatively little is known about this system in plants. In recent years, numerous reports have emerged about small, secreted peptides controlling different aspects of plant reproduction. Interestingly, most of these peptides are cysteine-rich, and there is convincing evidence suggesting multiple roles for related cysteine-rich peptides (CRPs) as signalling factors in developmental patterning as well as during plant pathogen responses and symbiosis. In this review, we discuss how CRPs are emerging as key signalling factors in regulating multiple aspects of vegetative growth and reproductive development in plants.

  12. Experimental evaluation of earthquake induced relay chattering

    International Nuclear Information System (INIS)

    Bandyopadhyay, K.; Hofmayer, C.; Shteyngart, S.

    1990-01-01

    An experimental evaluation of relay performance under vibratory environments is discussed in this paper. Single frequency excitation was used for most tests. Limited tests were performed with random multifrequency inputs. The capacity of each relay was established based on a two-millisecond chatter criterion. The experimental techniques are described and the effects of parameters in controlling the relay capacity levels are illustrated with test data. A wide variation of the capacity levels was observed due to the influence of parameters related to the design of the relay and nature of the input motion. 3 refs., 15 figs

  13. Machining Chatter Analysis for High Speed Milling Operations

    Science.gov (United States)

    Sekar, M.; Kantharaj, I.; Amit Siddhappa, Savale

    2017-10-01

    Chatter in high speed milling is characterized by time delay differential equations (DDE). Since closed form solution exists only for simple cases, the governing non-linear DDEs of chatter problems are solved by various numerical methods. Custom codes to solve DDEs are tedious to build, implement and not error free and robust. On the other hand, software packages provide solution to DDEs, however they are not straight forward to implement. In this paper an easy way to solve DDE of chatter in milling is proposed and implemented with MATLAB. Time domain solution permits the study and model of non-linear effects of chatter vibration with ease. Time domain results are presented for various stable and unstable conditions of cut and compared with stability lobe diagrams.

  14. Correlation analysis of motor current and chatter vibration in grinding using complex continuous wavelet coherence

    International Nuclear Information System (INIS)

    Liu, Yao; Wang, Xiufeng; Lin, Jing; Zhao, Wei

    2016-01-01

    Motor current is an emerging and popular signal which can be used to detect machining chatter with its multiple advantages. To achieve accurate and reliable chatter detection using motor current, it is important to make clear the quantitative relationship between motor current and chatter vibration, which has not yet been studied clearly. In this study, complex continuous wavelet coherence, including cross wavelet transform and wavelet coherence, is applied to the correlation analysis of motor current and chatter vibration in grinding. Experimental results show that complex continuous wavelet coherence performs very well in demonstrating and quantifying the intense correlation between these two signals in frequency, amplitude and phase. When chatter occurs, clear correlations in frequency and amplitude in the chatter frequency band appear and the phase difference of current signal to vibration signal turns from random to stable. The phase lead of the most correlated chatter frequency is the largest. With the further development of chatter, the correlation grows up in intensity and expands to higher order chatter frequency band. The analyzing results confirm that there is a consistent correlation between motor current and vibration signals in the grinding chatter process. However, to achieve accurate and reliable chatter detection using motor current, the frequency response bandwidth of current loop of the feed drive system must be wide enough to response chatter effectively. (paper)

  15. Does Online Chatter Really Matter? Dynamics of User-Generated Content and Stock Performance

    NARCIS (Netherlands)

    S. Tirunillai (Seshadri); G.J. Tellis (Gerard)

    2011-01-01

    textabstractUser-Generated Content in online platforms or chatter for short provides a valuable source of consumer feedback on market performance of firms. This study examines whether chatter can predict stock market performance, which metric of chatter has the strongest relationship, and what the

  16. Sliding Control with Chattering Elimination for Hydraulic Drives

    DEFF Research Database (Denmark)

    Schmidt, Lasse; Andersen, Torben Ole; Pedersen, Henrik C.

    2012-01-01

    This paper presents the development of a sliding mode control scheme with chattering elimination, generally applicable for position tracking control of electro-hydraulic valve-cylinder drives. The proposed control scheme requires only common data sheet information, no knowledge on load characteri......This paper presents the development of a sliding mode control scheme with chattering elimination, generally applicable for position tracking control of electro-hydraulic valve-cylinder drives. The proposed control scheme requires only common data sheet information, no knowledge on load...... controller is developed for the control derivative based on a reduced order model. Simulation results demonstrate strong robustness when subjected to parameter perturbations and that chattering is eliminated....

  17. Analytical Prediction of Three Dimensional Chatter Stability in Milling

    Science.gov (United States)

    Altintas, Yusuf

    The chip regeneration mechanism during chatter is influenced by vibrations in three directions when milling cutters with ball end, bull nose, or inclined cutting edges are used. A three dimensional chatter stability is modeled analytically in this article. The dynamic milling system is formulated as a function of cutter geometry, the frequency response of the machine tool structure at the cutting zone in three Cartesian directions, cutter engagement conditions and material property. The dynamic milling system with nonlinearities and periodic delayed differential equations is reduced to a three dimensional linear stability problem by approximations based on the physics of milling. The chatter stability lobes are predicted in the frequency domain using the proposed analytical solution, and verified experimentally in milling a Titanium alloy with a face milling cutter having circular inserts.

  18. The Microphone Feedback Analogy for Chatter in Machining

    Directory of Open Access Journals (Sweden)

    Tony Schmitz

    2015-01-01

    Full Text Available This paper provides experimental evidence for the analogy between the time-delay feedback in public address systems and chatter in machining. Machining stability theory derived using the Nyquist criterion is applied to predict the squeal frequency in a microphone/speaker setup. Comparisons between predictions and measurements are presented.

  19. Effects of relay chatter in seismic probabilistic safety analysis

    International Nuclear Information System (INIS)

    Reed, J.W.; Shiu, K.K.

    1985-01-01

    In the Zion and Indian Point Probabilistic Safety Studies, relay chatter was dismissed as a credible event and hence was not formally included in the analyses. Although little discussion is given in the Zion and Indian Point PSA documentation concerning the basis for this decision, it has been expressed informally that it was assumed that the operators will be able to reset all relays in a timely manner. Currently, it is the opinion of many professionals that this may be an oversimplification. The three basic areas which must be considered in addressing relay chatter include the fragility of the relays per se, the reliability of the operators to reset the relays and finally the systems response aspects. Each of these areas is reviewed and the implications for seismic PSA are discussed. Finally, recommendations for future research are given

  20. S-aryl-L-cysteine sulphoxides and related organosulphur compounds alter oral biofilm development and AI-2-based cell-cell communication.

    Science.gov (United States)

    Kasper, S H; Samarian, D; Jadhav, A P; Rickard, A H; Musah, R A; Cady, N C

    2014-11-01

    To design and synthesize a library of structurally related, small molecules related to homologues of compounds produced by the plant Petiveria alliacea and determine their ability to interfere with AI-2 cell-cell communication and biofilm formation by oral bacteria. Many human diseases are associated with persistent bacterial biofilms. Oral biofilms (dental plaque) are problematic as they are often associated with tooth decay, periodontal disease and systemic disorders such as heart disease and diabetes. Using a microplate-based approach, a bio-inspired small molecule library was screened for anti-biofilm activity against the oral species Streptococcus mutans UA159, Streptococcus sanguis 10556 and Actinomyces oris MG1. To complement the static screen, a flow-based BioFlux microfluidic system screen was also performed under conditions representative of the human oral cavity. Several compounds were found to display biofilm inhibitory activity in all three of the oral bacteria tested. These compounds were also shown to inhibit bioluminescence by Vibrio harveyi and were thus inferred to be quorum sensing (QS) inhibitors. Due to the structural similarity of these compounds to each other, and to key molecules in AI-2 biosynthetic pathways, we propose that these molecules potentially reduce biofilm formation via antagonism of QS or QS-related pathways. This study highlights the potential for a non-antimicrobial-based strategy, focused on AI-2 cell-cell signalling, to control the development of dental plaque. Considering that many bacterial species use AI-2 cell-cell signalling, as well as the increased concern of the use of antimicrobials in healthcare products, such an anti-biofilm approach could also be used to control biofilms in environments beyond the human oral cavity. © 2014 The Society for Applied Microbiology.

  1. Chatter detection in milling process based on VMD and energy entropy

    Science.gov (United States)

    Liu, Changfu; Zhu, Lida; Ni, Chenbing

    2018-05-01

    This paper presents a novel approach to detect the milling chatter based on Variational Mode Decomposition (VMD) and energy entropy. VMD has already been employed in feature extraction from non-stationary signals. The parameters like number of modes (K) and the quadratic penalty (α) need to be selected empirically when raw signal is decomposed by VMD. Aimed at solving the problem how to select K and α, the automatic selection method of VMD's based on kurtosis is proposed in this paper. When chatter occurs in the milling process, energy will be absorbed to chatter frequency bands. To detect the chatter frequency bands automatically, the chatter detection method based on energy entropy is presented. The vibration signal containing chatter frequency is simulated and three groups of experiments which represent three cutting conditions are conducted. To verify the effectiveness of method presented by this paper, chatter feather extraction has been successfully employed on simulation signals and experimental signals. The simulation and experimental results show that the proposed method can effectively detect the chatter.

  2. Intelligent Chatter Bot for Regulation Search

    Science.gov (United States)

    De Luise, María Daniela López; Pascal, Andrés; Saad, Ben; Álvarez, Claudia; Pescio, Pablo; Carrilero, Patricio; Malgor, Rafael; Díaz, Joaquín

    2016-01-01

    This communication presents a functional prototype, named PTAH, implementing a linguistic model focused on regulations in Spanish. Its global architecture, the reasoning model and short statistics are provided for the prototype. It is mainly a conversational robot linked to an Expert System by a module with many intelligent linguistic filters, implementing the reasoning model of an expert. It is focused on bylaws, regulations, jurisprudence and customized background representing entity mission, vision and profile. This Structure and model are generic enough to self-adapt to any regulatory environment, but as a first step, it was limited to an academic field. This way it is possible to limit the slang and data numbers. The foundations of the linguistic model are also outlined and the way the architecture implements the key features of the behavior.

  3. Visualization of N-acylhomoserine lactone-mediated cell-cell communication between bacteria colonizing the tomato rhizosphere

    DEFF Research Database (Denmark)

    Steidle, A.; Sigl, K.; Schuhegger, R.

    2001-01-01

    developed and characterized novel Gfp-based monitor strains that allow in situ visualization of AHL-mediated communication between individual cells in the plant rhizosphere. For this purpose, three Gfp-based AHL sensor plasmids that respond to different spectra of AHL molecules were transferred into AHL......-negative derivatives of Pseudomonas putida IsoF and Serratia liquefaciens MG1, two strains that are capable of colonizing tomato roots. These AHL monitor strains were used to visualize communication between defined bacterial populations in the rhizosphere of axenically grown tomato plants. Furthermore, we integrated...

  4. Model-based chatter stability prediction and detection for the turning of a flexible workpiece

    Science.gov (United States)

    Lu, Kaibo; Lian, Zisheng; Gu, Fengshou; Liu, Hunju

    2018-02-01

    Machining long slender workpieces still presents a technical challenge on the shop floor due to their low stiffness and damping. Regenerative chatter is a major hindrance in machining processes, reducing the geometric accuracies and dynamic stability of the cutting system. This study has been motivated by the fact that chatter occurrence is generally in relation to the cutting position in straight turning of slender workpieces, which has seldom been investigated comprehensively in literature. In the present paper, a predictive chatter model of turning a tailstock supported slender workpiece considering the cutting position change during machining is explored. Based on linear stability analysis and stiffness distribution at different cutting positions along the workpiece, the effect of the cutting tool movement along the length of the workpiece on chatter stability is studied. As a result, an entire stability chart for a single cutting pass is constructed. Through this stability chart the critical cutting condition and the chatter onset location along the workpiece in a turning operation can be estimated. The difference between the predicted tool locations and the experimental results was within 9% at high speed cutting. Also, on the basis of the predictive model the dynamic behavior during chatter that when chatter arises at some cutting location it will continue for a period of time until another specified location is arrived at, can be inferred. The experimental observation is in good agreement with the theoretical inference. In chatter detection respect, besides the delay strategy and overlap processing technique, a relative threshold algorithm is proposed to detect chatter by comparing the spectrum and variance of the acquired acceleration signals with the reference saved during stable cutting. The chatter monitoring method has shown reliability for various machining conditions.

  5. Enabling cell-cell communication via nanopore formation: structure, function and localization of the unique cell wall amidase AmiC2 of Nostoc punctiforme.

    Science.gov (United States)

    Büttner, Felix M; Faulhaber, Katharina; Forchhammer, Karl; Maldener, Iris; Stehle, Thilo

    2016-04-01

    To orchestrate a complex life style in changing environments, the filamentous cyanobacterium Nostoc punctiforme facilitates communication between neighboring cells through septal junction complexes. This is achieved by nanopores that perforate the peptidoglycan (PGN) layer and traverse the cell septa. The N-acetylmuramoyl-l-alanine amidase AmiC2 (Npun_F1846; EC 3.5.1.28) in N. punctiforme generates arrays of such nanopores in the septal PGN, in contrast to homologous amidases that mediate daughter cell separation after cell division in unicellular bacteria. Nanopore formation is therefore a novel property of AmiC homologs. Immunofluorescence shows that native AmiC2 localizes to the maturing septum. The high-resolution crystal structure (1.12 Å) of its catalytic domain (AmiC2-cat) differs significantly from known structures of cell splitting and PGN recycling amidases. A wide and shallow binding cavity allows easy access of the substrate to the active site, which harbors an essential zinc ion. AmiC2-cat exhibits strong hydrolytic activity in vitro. A single point mutation of a conserved glutamate near the zinc ion results in total loss of activity, whereas zinc removal leads to instability of AmiC2-cat. An inhibitory α-helix, as found in the Escherichia coli AmiC(E. coli) structure, is absent. Taken together, our data provide insight into the cell-biological, biochemical and structural properties of an unusual cell wall lytic enzyme that generates nanopores for cell-cell communication in multicellular cyanobacteria. The novel structural features of the catalytic domain and the unique biological function of AmiC2 hint at mechanisms of action and regulation that are distinct from other amidases. The AmiC2-cat structure has been deposited in the Protein Data Bank under accession number 5EMI. © 2016 Federation of European Biochemical Societies.

  6. Fuzzy sliding-mode control with low pass filter to reduce chattering ...

    Indian Academy of Sciences (India)

    S Balamurugan

    2017-10-13

    Oct 13, 2017 ... effect: an experimental validation on Quanser SRIP ... Stabilization of a single rotary inverted pendulum (SRIP) system is a benchmark nonlinear control problem. ..... SMC with sign function still exhibits the chattering phe-.

  7. Chattering-free fuzzy sliding-mode control strategy for uncertain chaotic systems

    International Nuclear Information System (INIS)

    Yau, H.-T.; Chen, C.-L.

    2006-01-01

    This paper proposes a chattering-free fuzzy sliding-mode control (FSMC) strategy for uncertain chaotic systems. A fuzzy logic control is used to replace the discontinuous sign function of the reaching law in traditional sliding-mode control (SMC), and hence a control input without chattering is obtained in the chaotic systems with uncertainties. Base on the Lyapunov stability theory, we address the design schemes of integration fuzzy sliding-mode control, where the reaching law is proposed by a set of linguistic rules and the control input is chattering free. The Genesio chaotic system is used to test the proposed control strategy and the simulation results show the FSMC not only can control the uncertain chaotic behaviors to a desired state without oscillator very fast, but also the switching function is smooth without chattering. This result implies that this strategy is feasible and effective for chaos control

  8. Experimental Investigation of Chatter Dynamics in Thin-walled Tubular Parts Turning

    OpenAIRE

    GERASIMENKO, Artem; GUSKOV, Mikhail; LORONG, Philippe; DUCHEMIN, Jérôme; GOUSKOV, Alexander

    2016-01-01

    Chatter prediction is nowadays frequently carried out for machining operations involving deformable parts or tools. These analyses are commonly based on the uncoupled elements of the system: frequency response of the deformable parts under non-rotating conditions and cutting law. The present investigation puts forward the dynamics of a thin-walled tubular part during straight axial turning undergoing chatter instability. Studied system’s peculiarities include quasi-static nominal cutting cond...

  9. Objective comparison of 4 nonlongitudinal ultrasound modalities regarding efficiency and chatter.

    Science.gov (United States)

    DeMill, David L; Zaugg, Brian E; Pettey, Jeff H; Jensen, Jason D; Jardine, Griffin J; Wong, Gilbert; Olson, Randall J

    2012-06-01

    To compare efficiency and chatter of Infiniti Ozil with and without Intelligent Phacoemulsification (IP) and the Signature Ellips with and without FX. John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. Experimental study. Brunescent 2.0 mm human lens cubes were created by an instrument devised for this study. Cubes were tested (10 per test) for time of particle removal (efficiency) and for the number of times the lens particle bounced off the tip (chatter) at 300 mm Hg and 550 mm Hg, 50% and 100% power, and 50% and 100% amplitudes (amplitude for Ozil only). Of the ultrasound settings, efficiency varied from a mean of 3.3 seconds ± 1.4 (SD) to 50.4 ± 11.7 seconds and chatter from 0.0 to 52.0 ± 16.7 bounces per run. The Ozil-IP was generally more efficient than the Ozil and the Ellips FX more efficient than the Ellips. At optimized values, the Ozil-IP and Ellips-FX were similar. In general, efficiency and chatter were better at 550 mm Hg and at 50% power. The amplitude effect was complex. Efficiency closely correlated with chatter (Pearson r(2) = .31, P<.0001). Objective comparison of phacoemulsification efficiency and chatter found that optimized Ozil-IP and Ellips-FX were similar in both parameters and in general, both performed better than preceding technology. The study parameters can significantly affect efficiency and chatter, which strongly correlate with each other. Copyright © 2012 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  10. Active chatter suppression with displacement-only measurement in turning process

    Science.gov (United States)

    Ma, Haifeng; Wu, Jianhua; Yang, Liuqing; Xiong, Zhenhua

    2017-08-01

    Regenerative chatter is a major hindrance for achieving high quality and high production rate in machining processes. Various active controllers have been proposed to mitigate chatter. However, most of existing controllers were developed on the basis of multi-states feedback of the system and state observers were usually needed. Moreover, model parameters of the machining process (mass, damping and stiffness) were required in existing active controllers. In this study, an active sliding mode controller, which employs a dynamic output feedback sliding surface for the unmatched condition and an adaptive law for disturbance estimation, is designed, analyzed, and validated for chatter suppression in turning process. Only displacement measurement is required by this approach. Other sensors and state observers are not needed. Moreover, it facilitates a rapid implementation since the designed controller is established without using model parameters of the turning process. Theoretical analysis, numerical simulations and experiments on a computer numerical control (CNC) lathe are presented. It shows that the chatter can be substantially attenuated and the chatter-free region can be significantly expanded with the presented method.

  11. Chatter suppression methods of a robot machine for ITER vacuum vessel assembly and maintenance

    International Nuclear Information System (INIS)

    Wu, Huapeng; Wang, Yongbo; Li, Ming; Al-Saedi, Mazin; Handroos, Heikki

    2014-01-01

    Highlights: •A redundant 10-DOF serial-parallel hybrid robot for ITER assembly and maintains is presented. •A dynamic model of the robot is developed. •A feedback and feedforward controller is presented to suppress machining vibration of the robot. -- Abstract: In the process of assembly and maintenance of ITER vacuum vessel (ITER VV), various machining tasks including threading, milling, welding-defects cutting and flexible hose boring are required to be performed from inside of ITER VV by on-site machining tools. Robot machine is a promising option for these tasks, but great chatter (machine vibration) would happen in the machining process. The chatter vibration will deteriorate the robot accuracy and surface quality, and even cause some damages on the end-effector tools and the robot structure itself. This paper introduces two vibration control methods, one is passive and another is active vibration control. For the passive vibration control, a parallel mechanism is presented to increase the stiffness of robot machine; for the active vibration control, a hybrid control method combining feedforward controller and nonlinear feedback controller is introduced for chatter suppression. A dynamic model and its chatter vibration phenomena of a hybrid robot is demonstrated. Simulation results are given based on the proposed hybrid robot machine which is developed for the ITER VV assembly and maintenance

  12. Chatter suppression methods of a robot machine for ITER vacuum vessel assembly and maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Huapeng; Wang, Yongbo, E-mail: yongbo.wang@lut.fi; Li, Ming; Al-Saedi, Mazin; Handroos, Heikki

    2014-10-15

    Highlights: •A redundant 10-DOF serial-parallel hybrid robot for ITER assembly and maintains is presented. •A dynamic model of the robot is developed. •A feedback and feedforward controller is presented to suppress machining vibration of the robot. -- Abstract: In the process of assembly and maintenance of ITER vacuum vessel (ITER VV), various machining tasks including threading, milling, welding-defects cutting and flexible hose boring are required to be performed from inside of ITER VV by on-site machining tools. Robot machine is a promising option for these tasks, but great chatter (machine vibration) would happen in the machining process. The chatter vibration will deteriorate the robot accuracy and surface quality, and even cause some damages on the end-effector tools and the robot structure itself. This paper introduces two vibration control methods, one is passive and another is active vibration control. For the passive vibration control, a parallel mechanism is presented to increase the stiffness of robot machine; for the active vibration control, a hybrid control method combining feedforward controller and nonlinear feedback controller is introduced for chatter suppression. A dynamic model and its chatter vibration phenomena of a hybrid robot is demonstrated. Simulation results are given based on the proposed hybrid robot machine which is developed for the ITER VV assembly and maintenance.

  13. Analytical expressions for chatter analysis in milling operations with one dominant mode

    Science.gov (United States)

    Iglesias, A.; Munoa, J.; Ciurana, J.; Dombovari, Z.; Stepan, G.

    2016-08-01

    In milling, an accurate prediction of chatter is still one of the most complex problems in the field. The presence of these self-excited vibrations can spoil the surface of the part and can also cause a large reduction in tool life. The stability diagrams provide a practical selection of the optimum cutting conditions determined either by time domain or frequency domain based methods. Applying these methods parametric or parameter traced representations of the linear stability limits can be achieved by solving the corresponding eigenvalue problems. In this work, new analytical formulae are proposed related to the parameter domains of both Hopf and period doubling type stability boundaries emerging in the regenerative mechanical model of time periodical milling processes. These formulae are useful to enrich and speed up the currently used numerical methods. Also, the destabilization mechanism of double period chatter is explained, creating an analogy with the chatter related to the Hopf bifurcation, considering one dominant mode and using concepts established by the Pioneers of chatter research.

  14. Automatic in-process chatter avoidance in the high-speed milling process

    NARCIS (Netherlands)

    Dijk, van N.J.M.; Doppenberg, E.J.J.; Faassen, R.P.H.; Wouw, van de N.; Oosterling, J.A.J.; Nijmeijer, H.

    2010-01-01

    High-speed milling is often used in industry to maximize productivity of the manufacturing of high-technology components, such as aeronautical components, mold, and dies. The occurrence of chatter highly limits the efficiency and accuracy of high-speed milling operations. In this paper, two control

  15. Sliding mode controller gain adaptation and chattering reduction techniques for DSP-based PM DC motor drives

    DEFF Research Database (Denmark)

    Dal, Mehmet; Teodorescu, Remus

    2011-01-01

    In order to achieve and maintain the prospective benefits of sliding mode control (SMC) methodology, the phenomenon known as “chattering”, the main obstacle encountered in real-time applications, has to be suppressed. In this study, two promising switching control gain adaptation and chattering...... reduction techniques are investigated, and the effectiveness of chattering suppression for current regulation of PM DC drives is tested. The sampling rate was also examined to determine how it affects the amplitude of chattering. This paper concentrates on various combinations of observer-based methods...... in order to find the best solution for chattering reduction. To find a practical solution a tunable low-pass filter (LPF) was used to average the discontinuous control term. The validity of the existing conditions for the gain adaptation methods are examined and observer gain value was determined through...

  16. Influence of Chatter of VMC Arising During End Milling Operation and Cutting Conditions on Quality of Machined Surface

    Directory of Open Access Journals (Sweden)

    A.K.M.N. Amin, M.A. Rizal, and M. Razman

    2012-08-01

    Full Text Available Machine tool chatter is a dynamic instability of the cutting process. Chatter results in poor part surface finish, damaged cutting tool, and an irritating and unacceptable noise. Exten¬sive research has been undertaken to study the mechanisms of chatter formation. Efforts have been also made to prevent the occurrence of chatter vibration. Even though some progress have been made, fundamental studies on the mechanics of metal cutting are necessary to achieve chatter free operation of CNC machine tools to maintain their smooth operating cycle. The same is also true for Vertical Machining Centres (VMC, which operate at high cutting speeds and are capable of offering high metal removal rates. The present work deals with the effect of work materials, cutting conditions and diameter of end mill cutters on the frequency-amplitude characteristics of chatter and on machined surface roughness. Vibration data were recorded using an experimental rig consisting of KISTLER 3-component dynamometer model 9257B, amplifier, scope meters and a PC.  Three different types of vibrations were observed. The first type was a low frequency vibration, associated with the interrupted nature of end mill operation. The second type of vibration was associated with the instability of the chip formation process and the third type was due to chatter. The frequency of the last type remained practically unchanged over a wide range of cutting speed.  It was further observed that chip-tool contact processes had considerable effect on the roughness of the machined surface.Key Words: Chatter, Cutting Conditions, Stable Cutting, Surface Roughness.

  17. Robust Non-Chattering Observer Based Sliding Control Concept for Electro-Hydraulic Drives

    DEFF Research Database (Denmark)

    Schmidt, Lasse; Andersen, Torben Ole; Pedersen, Henrik C.

    2013-01-01

    This paper presents an observer-based sliding mode control concept with chattering reduction, generally applicable for position tracking control of electro-hydraulic valve-cylinder drives (VCD's). The proposed control concept requires only common data sheet information and no knowledge on load...... extensive knowledge on system parameters nor advanced control theory. In order to accomplish this task, an integral sliding mode controller designed for the control derivative employing state observation is proposed, based on a generalized reduced order model structure of a VCD with unmatched valve ow......- and cylinder asymmetries. It is shown that limited attention can be given to bounds on parameter estimates, that chattering is reduced and the number of tuning parameters is reduced to the level seen in conventional PID schemes. Furthermore, simulation results demonstrate a high level of robustness when...

  18. A dynamic model of cylindrical plunge grinding process for chatter phenomena investigation

    Directory of Open Access Journals (Sweden)

    Lajmert Paweł

    2018-01-01

    Full Text Available In the paper, chatter vibrations in the cylindrical plunge grinding process are investigated. An improved model of the grinding process was developed which is able to simulate self-excited vibrations due to a regenerative effect on the workpiece and the grinding wheel surface. The model includes a finite-element model of the workpiece, two degrees of freedom model of the grinding wheel headstock and a model of wheel-workpiece geometrical interferences. The model allows to studying the influence of different factors, i.e. workpiece and machine parameters as well as grinding conditions on the stability limit and a chatter vibration growth rate. At the end, simulation results are shown and compared with exemplified real grinding results.

  19. Delay dynamical systems and applications to nonlinear machine-tool chatter

    International Nuclear Information System (INIS)

    Fofana, M.S.

    2003-01-01

    The stability behaviour of machine chatter that exhibits Hopf and degenerate bifurcations has been examined without the assumption of small delays between successive cuts. Delay dynamical system theory leading to the reduction of the infinite-dimensional character of the governing delay differential equations (DDEs) to a finite-dimensional set of ordinary differential equations have been employed. The essential mathematical arguments for these systems in the context of retarded DDEs are summarized. Then the application of these arguments in the stability study of machine-tool chatter with multiple time delays is presented. Explicit analytical expressions ensuring stable and unstable machining when perturbations are periodic, stochastic and nonlinear have been derived using the integral averaging method and Lyapunov exponents

  20. Friction Pull Plug and Material Configuration for Anti-Chatter Friction Pull Plug Weld

    Science.gov (United States)

    Littell, Justin Anderson (Inventor)

    2016-01-01

    A friction pull plug is provided for use in forming a plug weld in a hole in a material. The friction pull plug includes a shank and a series of three frustoconical sections. The relative sizes of the sections assure that a central one of the sections defines the initial contact point between the hole's sides. The angle defined by the central one of the sections reduces or eliminates chatter as the plug is pulled into the hole.

  1. Relay chatter and operator response after a large earthquake: An improved PRA methodology with case studies

    International Nuclear Information System (INIS)

    Budnitz, R.J.; Lambert, H.E.; Hill, E.E.

    1987-08-01

    The purpose of this project has been to develop and demonstrate improvements in the PRA methodology used for analyzing earthquake-induced accidents at nuclear power reactors. Specifically, the project addresses methodological weaknesses in the PRA systems analysis used for studying post-earthquake relay chatter and for quantifying human response under high stress. An improved PRA methodology for relay-chatter analysis is developed, and its use is demonstrated through analysis of the Zion-1 and LaSalle-2 reactors as case studies. This demonstration analysis is intended to show that the methodology can be applied in actual cases, and the numerical values of core-damage frequency are not realistic. The analysis relies on SSMRP-based methodologies and data bases. For both Zion-1 and LaSalle-2, assuming that loss of offsite power (LOSP) occurs after a large earthquake and that there are no operator recovery actions, the analysis finds very many combinations (Boolean minimal cut sets) involving chatter of three or four relays and/or pressure switch contacts. The analysis finds that the number of min-cut-set combinations is so large that there is a very high likelihood (of the order of unity) that at least one combination will occur after earthquake-caused LOSP. This conclusion depends in detail on the fragility curves and response assumptions used for chatter. Core-damage frequencies are calculated, but they are probably pessimistic because assuming zero credit for operator recovery is pessimistic. The project has also developed an improved PRA methodology for quantifying operator error under high-stress conditions such as after a large earthquake. Single-operator and multiple-operator error rates are developed, and a case study involving an 8-step procedure (establishing feed-and-bleed in a PWR after an earthquake-initiated accident) is used to demonstrate the methodology

  2. Eddy currents self-tuning dynamic vibration absorber for machine tool chatter suppression

    OpenAIRE

    Aguirre , Gorka; Gorostiaga , Mikel; Porchez , Thomas; Munoa , Jokin

    2013-01-01

    International audience; The current trend in machine tool design aims at stiffer machines with lowerinfluence of friction, leading to faster and more precise machines. However, this is atthe expense of reducing the machine damping, which is mainly produced by friction,and thus increasing the risk of suffering from a self-excited vibration named chatter,which limits the productivity of the process. Dynamic vibration absorbers (DVAs)offer a relatively simple and low cost solution to reduce chat...

  3. Chattering-Free Adaptive Sliding Mode Control for Attitude Tracking of Spacecraft with External Disturbance

    Directory of Open Access Journals (Sweden)

    Xuxi Zhang

    2014-01-01

    Full Text Available The attitude tracking problem of spacecraft in the presence of unknown disturbance is investigated. By using the adaptive control technique and the Lyapunov stability theory, a chattering-free adaptive sliding mode control law is proposed for the attitude tracking problem of spacecraft with unknown disturbance. Simulation results are employed to demonstrate the effectiveness of the proposed control design technique in this paper.

  4. Chatter reduction in boring process by using piezoelectric shunt damping with experimental verification

    Science.gov (United States)

    Yigit, Ufuk; Cigeroglu, Ender; Budak, Erhan

    2017-09-01

    Chatter is a self-excited type of vibration that develops during machining due to process-structure dynamic interactions resulting in modulated chip thickness. Chatter is an important problem as it results in poor surface quality, reduced productivity and tool life. The stability of a cutting process is strongly influenced by the frequency response function (FRF) at the cutting point. In this study, the effect of piezoelectric shunt damping on chatter vibrations in a boring process is studied. In piezoelectric shunt damping method, an electrical impedance is connected to a piezoelectric transducer which is bonded on cutting tool. Electrical impedance of the circuit consisting of piezoceramic transducer and passive shunt is tuned to the desired natural frequency of the cutting tool in order to maximize damping. The optimum damping is achieved in analytical and finite element models (FEM) by using a genetic algorithm focusing on the real part of the tool point FRF rather than the amplitude. Later, a practical boring bar is considered where the optimum circuit parameters are obtained by the FEM. Afterwards, the effect of the optimized piezoelectric shunt damping on the dynamic rigidity and absolute stability limit of the cutting process are investigated experimentally by modal analysis and cutting tests. It is both theoretically and experimentally shown that application of piezoelectric shunt damping results in a significant increase in the absolute stability limit in boring operations.

  5. Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication?

    International Nuclear Information System (INIS)

    Clarkin, Claire E.; Garonna, Elena; Pitsillides, Andrew A.; Wheeler-Jones, Caroline P.D.

    2008-01-01

    In bone, angiogenesis must be initiated appropriately, but limited once remodelling or repair is complete. Our recent findings have supported a role for prostaglandins (PG), known modulators of osteoblast (OB) and endothelial cell (EC) behaviour, in facilitating VEGF-mediated paracrine communication from OBs to 'remotely located' ECs, but the mechanism(s) regulating OB:EC crosstalk when these cells are closely opposed are undefined. In this study we have examined: (i) the effects of exogenous PGE 2 on VEGF-driven events in ECs, and (ii) the role of endogenous COX-2-derived prostanoids in mediating communication between intimately opposed OBs and ECs in direct contact. Exposure of ECs to PGE 2 increased ERK1/2 phosphorylation, COX-2 induction, 6-keto-PGF 1α release and EC proliferation. In contrast, PGE 2 attenuated VEGF 165 -induced VEGFR2/Flk1 phosphorylation, ERK1/2 activation and proliferation of ECs, suggesting that exogenous PGE 2 restricts the actions of VEGF. However, the COX-2-selective inhibitor, NS398, also attenuated VEGF-induced proliferation, implying a distinct role for endogenous COX-2 activity in regulating EC behaviour. To examine the effect of OB:EC proximity and the role of COX-2 products further, we used a confrontational co-culture model. These studies showed that COX-2 blockade with NS398 enhanced EC-dependent increases in OB differentiation, that this effect was reversed by exogenous PGH 2 (immediate COX-2 product), and that exogenous VEGF did not influence EC-dependent OB differentiation under these conditions. Our findings indicate that locally produced prostanoids may serve distinct roles depending on OB:EC proximity and negatively modulate VEGF-mediated changes in EC behaviour when these cells are closely opposed to control angiogenesis during bone (re)modelling

  6. The impact of seismically-induced relay chatter on nuclear plant risk

    International Nuclear Information System (INIS)

    Bley, D.C.; McIntyre, T.J.; Smith, B.; Kassawara, R.P.

    1987-01-01

    This paper describes a systematic scheme for analyzing the impact of relay chatter that is amenable to both PRA analysis and seismic margins analysis. It uses knowledge of the systems engineering of the plant to bound the scope of the problem to a tractable size and has been applied to both the Diablo Canyon PRA and the EPRI seismic margines program trial evaluation at the Catawba Nuclear Power Plant. It has also been coordinated with similar EPRI-sponsored work on relay functionality for the Seismic Qualification Utility Group. (orig./HP)

  7. Chattering-free sliding mode observer for speed sensorless control of PMSM

    Directory of Open Access Journals (Sweden)

    Mahmoud M. Gaballah

    2017-07-01

    Full Text Available This article presents a new speed observer based on fuzzy logic for speed sensorless control applications of permanent magnet synchronous motor “PMSM”. The switch function in traditional Sliding Mode Observer “SMO” is replaced by a rule based fuzzy logic system. The proposed observer not only improves the system dynamic performance during disturbances or parameter variations, but also has a high accuracy tracking performance with sufficient chattering reduction. The validity of the new observer corroborated through experimental results using TMS320F28069M Digital Signal Processor “DSP”.

  8. Preventing chatter vibrations in heavy-duty turning operations in large horizontal lathes

    Science.gov (United States)

    Urbikain, G.; Campa, F.-J.; Zulaika, J.-J.; López de Lacalle, L.-N.; Alonso, M.-A.; Collado, V.

    2015-03-01

    Productivity and surface finish are typical user manufacturer requirements that are restrained by chatter vibrations sooner or later in every machining operation. Thus, manufacturers are interested in knowing, before building the machine, the dynamic behaviour of each machine structure with respect to another. Stability lobe graphs are the most reliable approach to analyse the dynamic performance. During heavy rough turning operations a model containing (a) several modes, or (b) modes with non-conventional (Cartesian) orientations is necessary. This work proposes two methods which are combined with multimode analysis to predict chatter in big horizontal lathes. First, a traditional single frequency model (SFM) is used. Secondly, the modern collocation method based on the Chebyshev polynomials (CCM) is alternatively studied. The models can be used to identify the machine design features limiting lathe productivity, as well as the threshold values for choosing good cutting parameters. The results have been compared with experimental tests in a horizontal turning centre. Besides the model and approach, this work offers real worthy values for big lathes, difficult to be got from literature.

  9. Chattering-Free Neuro-Sliding Mode Control of 2-DOF Planar Parallel Manipulators

    Directory of Open Access Journals (Sweden)

    Tien Dung Le

    2013-01-01

    Full Text Available This paper proposes a novel chattering free neuro-sliding mode controller for the trajectory tracking control of two degrees of freedom (DOF parallel manipulators which have a complicated dynamic model, including modelling uncertainties, frictional uncertainties and external disturbances. A feedforward neural network (NN is combined with an error estimator to completely compensate the large nonlinear uncertainties and external disturbances of the parallel manipulators. The online weight tuning algorithms of the NN and the structure of the error estimator are derived with the strict theoretical stability proof of the Lyapunov theorem. The upper bound of uncertainties and the upper bound of the approximation errors are not required to be known in advance in order to guarantee the stability of the closed-loop system. The example simulation results show the effectiveness of the proposed control strategy for the tracking control of a 2-DOF parallel manipulator. It results in its being chattering-free, very small tracking errors and its robustness against uncertainties and external disturbances.

  10. The impact of relay chatter on the availability of plant systems following a seismic event

    International Nuclear Information System (INIS)

    Evans, M.G.K.; Su, Y.J.

    1985-01-01

    In performing a risk analysis of a nuclear power plant, one of the most important factors in determining the availability of those systems required to safely shut down the plant is the impact of common cause failures resulting from such events as fire, flooding or earthquakes. In the latter case it is particularly important to do a thorough analysis of the effects of the earthquake for plants built in zones of high seismicity such as the western United States, Japan or Taiwan. Much work has been done on the susceptibility of components to gross failure but little on the possibilities of relay chatter leading to the unavailability of many systems as the result of lock out of pumps or the changed status of valves. In this paper the authors look at the potential for electrical breaker failure and found that it is possible for a significant number of breakers supplying emergency pumps to be locked out following earthquakes such that the only other failure may well have been a loss of offsite power due to failure of switchyard insulators. They also identified the potential for individual valve operation within a system as the result of relay chatter, and the impact on the overall system availability. Finally they show how this can be incorporated into the quantification of the overall impact of the earthquake

  11. Deutsch, Doyc or Doitsch? Chatters as Languagers--The Case of a German-Turkish Chat Room

    Science.gov (United States)

    Hinnenkamp, Volker

    2008-01-01

    The paper looks at the process of online-languaging of adolescents with a migratory and ethnic Turkish background in a diasporic chat room. The multiple resources and voices used are analysed. One particular example is looked at more thoroughly to illustrate the process of languaging and how it is legitimised by the chatters themselves. Finally,…

  12. ROLE OF DISCRETE NATURE OF CHIP FORMATION AND NATURAL VIBRATIONS OF SYSTEM COMPONENTS IN CHATTER FORMATION DURING METAL CUTTING

    Directory of Open Access Journals (Sweden)

    A. K. M. Nurulamin

    2010-05-01

    Full Text Available In the present work a review of the existing theories of chatter formation has been conducted and the weaknesses of the most widely accepted ‘Regenerative Chatter theory’ in explaining various phenomena related to chatter formation have been identified. An attempt has been made in this work to determine the common causes of chatter formation in different metal cutting operations, namely, turning, thread cutting and end milling conducted on plain carbon steel AISI 1040. Experimental investigations have been conducted during the above types of machining processes to identify the marks of instability and chatter on the formed chips. It has been identified that in all the three machining operations the chips formed show a common type of discreteness in the form of secondary saw teeth, which appear at the free edge of the chip. Mechanism of formation of these teeth has been studied and the frequencies of their formation have been determined for different cutting conditions. Apart from the secondary saw teeth primary saw teeth have also been identified at the main section of the chip and their frequencies were also determined. At the same time the natural vibrations of the main system components have been identified and the acceleration amplitudes at the prominent natural frequencies during actual machining were recoded using a dedicated vibration monitoring system. The frequencies of secondary chip serration and the natural frequencies of the system components were plotted against cutting speed. Acceleration amplitudes at the prominent natural frequencies were also plotted separately against cutting force. Based on comparison and analysis of these two frequency and amplitude graphs it was concluded that chatter (vibration with relatively high amplitude appears in the system when the frequency of secondary saw teeth approaches values equal to half or integer multiple of a prominent natural frequency of the system resulting in resonance. In the

  13. A Discrete-Time Chattering Free Sliding Mode Control with Multirate Sampling Method for Flight Simulator

    Directory of Open Access Journals (Sweden)

    Yunjie Wu

    2013-01-01

    Full Text Available In order to improve the tracking accuracy of flight simulator and expend its frequency response, a multirate-sampling-method-based discrete-time chattering free sliding mode control is developed and imported into the systems. By constructing the multirate sampling sliding mode controller, the flight simulator can perfectly track a given reference signal with an arbitrarily small dynamic tracking error, and the problems caused by a contradiction of reference signal period and control period in traditional design method can be eliminated. It is proved by theoretical analysis that the extremely high dynamic tracking precision can be obtained. Meanwhile, the robustness is guaranteed by sliding mode control even though there are modeling mismatch, external disturbances and measure noise. The validity of the proposed method is confirmed by experiments on flight simulator.

  14. Porcine lens nuclei as a model for comparison of 3 ultrasound modalities regarding efficiency and chatter.

    Science.gov (United States)

    Oakey, Zack B; Jensen, Jason D; Zaugg, Brian E; Radmall, Bryce R; Pettey, Jeff H; Olson, Randall J

    2013-08-01

    To validate a porcine lens model by comparing density and ultrasound (US) with known human standards using the Infiniti Ozil with Intelligent Phacoemulsification (torsional), Whitestar Signature Micropulse (longitudinal), and Ellips FX (transversal) modalities. Department of Ophthalmology and Visual Sciences, John A. Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. Experimental study. Lens nuclei were formalin soaked in hour-based intervals and divided into 2.0 mm cubes. Density was characterized by crushing experiments and compared with known human measures. Efficiency and chatter were examined. The mean weight to cut thickness in half ranged from 16.9 g ± 5.5 (SD) in the 0-hour group to 121.3 ± 47.5 gm in the 4-hour group. Lenses in the 2-hour group (mean 70.2 ± 19.1 g) best matched human density (P=.215). The mean efficiency ranged from 0.432 ± 0.178 seconds to 9.111 ± 2.925 seconds; chatter ranged from zero to 1.85 ± 1.927 bounces. No significant difference was detected when comparing the 2-hour formalin group with human lenses in torsional and transversal US. There was no significant difference between transversal and torsional modalities, consistent with human studies. Although longitudinal (6 milliseconds on, 12 milliseconds off) was significantly more efficient at 50% power than at 25%, there was no significant difference compared with transversal or torsional US. Animal lenses soaked for 2 hours in formalin were most comparable to human lenses. Longitudinal US may be an acceptable alternative to torsional and transversal US. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  15. Prediction of dynamic cutting force and regenerative chatter stability in inserted cutters milling

    Science.gov (United States)

    Li, Zhongqun; Liu, Qiang; Yuan, Songmei; Huang, Kaisheng

    2013-05-01

    Currently, the modeling of cutting process mainly focuses on two aspects: one is the setup of the universal cutting force model that can be adapted to a broader cutting condition; the other is the setup of the exact cutting force model that can accurately reflect a true cutting process. However, there is little research on the prediction of chatter stablity in milling. Based on the generalized mathematical model of inserted cutters introduced by ENGIN, an improved geometrical, mechanical and dynamic model for the vast variety of inserted cutters widely used in engineering applications is presented, in which the average directional cutting force coefficients are obtained by means of a numerical approach, thus leading to an analytical determination of stability lobes diagram (SLD) on the axial depth of cut. A new kind of SLD on the radial depth of cut is also created to satisfy the special requirement of inserted cutter milling. The corresponding algorithms used for predicting cutting forces, vibrations, dimensional surface finish and stability lobes in inserted cutter milling under different cutting conditions are put forward. Thereafter, a dynamic simulation module of inserted cutter milling is implemented by using hybrid program of Matlab with Visual Basic. Verification tests are conducted on a vertical machine center for Aluminum alloy LC4 by using two different types of inserted cutters, and the effectiveness of the model and the algorithm is verified by the good agreement of simulation result with that of cutting tests under different cutting conditions. The proposed model can predict the cutting process accurately under a variety of cutting conditions, and a high efficient and chatter-free milling operation can be achieved by a cutting condition optimization in industry applications.

  16. Delay differential equations via the matrix Lambert W function and bifurcation analysis: application to machine tool chatter.

    Science.gov (United States)

    Yi, Sun; Nelson, Patrick W; Ulsoy, A Galip

    2007-04-01

    In a turning process modeled using delay differential equations (DDEs), we investigate the stability of the regenerative machine tool chatter problem. An approach using the matrix Lambert W function for the analytical solution to systems of delay differential equations is applied to this problem and compared with the result obtained using a bifurcation analysis. The Lambert W function, known to be useful for solving scalar first-order DDEs, has recently been extended to a matrix Lambert W function approach to solve systems of DDEs. The essential advantages of the matrix Lambert W approach are not only the similarity to the concept of the state transition matrix in lin ear ordinary differential equations, enabling its use for general classes of linear delay differential equations, but also the observation that we need only the principal branch among an infinite number of roots to determine the stability of a system of DDEs. The bifurcation method combined with Sturm sequences provides an algorithm for determining the stability of DDEs without restrictive geometric analysis. With this approach, one can obtain the critical values of delay, which determine the stability of a system and hence the preferred operating spindle speed without chatter. We apply both the matrix Lambert W function and the bifurcation analysis approach to the problem of chatter stability in turning, and compare the results obtained to existing methods. The two new approaches show excellent accuracy and certain other advantages, when compared to traditional graphical, computational and approximate methods.

  17. N-cadherin in adult rat cardiomyocytes in culture. II. Spatio-temporal appearance of proteins involved in cell-cell contact and communication. Formation of two distinct N-cadherin/catenin complexes.

    Science.gov (United States)

    Hertig, C M; Butz, S; Koch, S; Eppenberger-Eberhardt, M; Kemler, R; Eppenberger, H M

    1996-01-01

    The spatio-temporal appearance and distribution of proteins forming the intercalated disc were investigated in adult rat cardiomyocytes (ARC). The 'redifferentiation model' of ARC involves extensive remodelling of the plasma membrane and of the myofibrillar apparatus. It represents a valuable system to elucidate the formation of cell-cell contact between cardiomyocytes and to assess the mechanisms by which different proteins involved in the cell-cell adhesion process are sorted in a precise manner to the sites of function. Appearance of N-cadherin, the catenins and connexin43 within newly formed adherens and gap junctions was studied. Here first evidence is provided for a formation of two distinct and separable N-cadherin/catenin complexes in cardiomyocytes. Both complexes are composed of N-cadherin and alpha-catenin which bind to either beta-catenin or plakoglobin in a mutually exclusive manner. The two N-cadherin/catenin complexes are assumed to be functionally involved in the formation of cell-cell contacts in ARC; however, the differential appearance and localization of the two types of complexes may also point to a specific role during ARC differentiation. The newly synthesized beta-catenin containing complex is more abundant during the first stages in culture after ARC isolation, while the newly synthesized plakoglobin containing complex progressively accumulates during the morphological changes of ARC. ARC formed a tissue-like pattern in culture whereby the new cell-cell contacts could be dissolved through Ca2+ depletion. Presence of cAMP and replenishment of Ca2+ content in the culture medium not only allowed reformation of cell-cell contacts but also affected the relative protein ratio between the two N-cadherin/catenin complexes, increasing the relative amount of newly synthesized beta-catenin over plakoglobin at a particular stage of ARC differentiation. The clustered N-cadherin/catenin complexes at the plasma membrane appear to be a prerequisite for the

  18. Influence of damping coefficient from permanent magnets on chatter formation during end milling of titanium alloy (Ti-6Al-4V)

    International Nuclear Information System (INIS)

    Sulaiman, S A; Amin, A N

    2015-01-01

    In machining operations, chatter is undesirable due to its adverse effects on the product quality, operation cost, machining accuracy and machine tool life. It is also responsible for reducing output. Chatter is a self-excitation phenomenon occurring in machine tools, in which the cutting process tends to lower the damping capacity of the machine structural components ending in an unstable behavior of the system. Chatter arises due to resonance when the vibrations of the instability of chip formation and the natural vibration modes of the machine-system components coincide. This paper focuses on the influence of damping coefficient from permanent magnets on chip serration frequency as an approach of minimizing chatter in end milling of Titanium alloy (Ti6Al4V). The method consists of two ferrite permanent magnet bars (dimensions: 1' × 6' × 3'), mounted 5mm from the cutting tool using a specially designed fixture which provided a uniform magnetic field of 2500-2700 Gausses. A titanium alloy Ti6Al4V block was then end milled using uncoated WC-Co inserts. A sequence of 15 experimental runs was conducted based on a small Central Composite Design (CCD) model in Response Surface Methodology (RSM). The primary (independent) parameters were: cutting speed, feed, and depth of cut. The data acquisition system comprised a vibration sensor (accelerometer) and a signal conditioning unit was used to measure the vibration data. The resultant vibrations were then analyzed using the DASYLab 5.6 software. Machining tests were conducted for two different conditions - with and without the application of magnets. Scanning Electron Microscope (SEM) was used to measure the chip segmentations. The SEM analysis of chip serrations demonstrated that the chip serration frequency were more stable while cutting under the presence of permanent magnets due to lower intensity of chatter. (paper)

  19. Influence of damping coefficient from permanent magnets on chatter formation during end milling of titanium alloy (Ti-6Al-4V)

    Science.gov (United States)

    Sulaiman, S. A.; Amin, A. N.

    2015-12-01

    In machining operations, chatter is undesirable due to its adverse effects on the product quality, operation cost, machining accuracy and machine tool life. It is also responsible for reducing output. Chatter is a self-excitation phenomenon occurring in machine tools, in which the cutting process tends to lower the damping capacity of the machine structural components ending in an unstable behavior of the system. Chatter arises due to resonance when the vibrations of the instability of chip formation and the natural vibration modes of the machine-system components coincide. This paper focuses on the influence of damping coefficient from permanent magnets on chip serration frequency as an approach of minimizing chatter in end milling of Titanium alloy (Ti6Al4V). The method consists of two ferrite permanent magnet bars (dimensions: 1" × 6" × 3"), mounted 5mm from the cutting tool using a specially designed fixture which provided a uniform magnetic field of 2500-2700 Gausses. A titanium alloy Ti6Al4V block was then end milled using uncoated WC-Co inserts. A sequence of 15 experimental runs was conducted based on a small Central Composite Design (CCD) model in Response Surface Methodology (RSM). The primary (independent) parameters were: cutting speed, feed, and depth of cut. The data acquisition system comprised a vibration sensor (accelerometer) and a signal conditioning unit was used to measure the vibration data. The resultant vibrations were then analyzed using the DASYLab 5.6 software. Machining tests were conducted for two different conditions - with and without the application of magnets. Scanning Electron Microscope (SEM) was used to measure the chip segmentations. The SEM analysis of chip serrations demonstrated that the chip serration frequency were more stable while cutting under the presence of permanent magnets due to lower intensity of chatter.

  20. A Hybrid Scheme Motion Controller by Sliding Mode and Two-Degree-of-Freedom Controls to Minimize the Chattering

    Directory of Open Access Journals (Sweden)

    Chiu-Keng Lai

    2014-01-01

    Full Text Available Sliding mode control (SMC is rapped for the chattering due to high gain control. However, high gain control causes the system robust. For developing a system with robustness of SMC, a servo motor motion controller combining the two-degree-of-freedom (2DOF system and SMC is proposed. The discussed motion type is point-to-point control with the constraint of trapezoid velocity profile. SMC is designed to guide the motor motion to follow a predefined trail, and the inner 2DOF system is used to compensate the deterioration due to the adoption of load observer. The proposed hybrid system is realized on a PC-based motion controller, and the validness is verified by simulation and experimental results.

  1. A new technical approach to quantify cell-cell adhesion forces by AFM

    International Nuclear Information System (INIS)

    Puech, Pierre-Henri; Poole, Kate; Knebel, Detlef; Muller, Daniel J.

    2006-01-01

    Cell-cell adhesion is a complex process that is involved in the tethering of cells, cell-cell communication, tissue formation, cell migration and the development and metastasis of tumors. Given the heterogeneous and complex nature of cell surfaces it has previously proved difficult to characterize individual cell-cell adhesion events. Force spectroscopy, using an atomic force microscope, is capable of resolving such individual cell-cell binding events, but has previously been limited in its application due to insufficient effective pulling distances. Extended pulling range is critical in studying cell-cell interactions due to the potential for large cell deformations. Here we describe an approach to such experiments, where the sample stage can be moved 100 μm in the z-direction, by closed loop, linearized piezo elements. Such an approach enables an increase in pulling distance sufficient for the observation of long-distance cell-unbinding events without reducing the imaging capabilities of the atomic force microscope. The atomic force microscope head and the piezo-driven sample stage are installed on an inverted optical microscope fitted with a piezo-driven objective, to allow the monitoring of cell morphology by conventional light microscopy, concomitant with force spectroscopy measurements. We have used the example of the WM115 melanoma cell line binding to human umbilical vein endothelial cells to demonstrate the capabilities of this system and the necessity for such an extended pulling range when quantifying cell-cell adhesion events

  2. Validating a Conceptual Framework for the Core Concept of ”Cell-cell Communication”

    Czech Academy of Sciences Publication Activity Database

    Michael, J.; Martinková, Patrícia; McFarland, J.L.; Wright, A.; Cliff, W.; Modell, H.; Wenderoth, M.P.

    2017-01-01

    Roč. 41, č. 2 (2017), s. 260-265 ISSN 1043-4046 R&D Projects: GA ČR GJ15-15856Y Institutional support: RVO:67985807 Keywords : conceptual framework * core concept * cell-cell communication * physiology Subject RIV: AM - Education OBOR OECD: Education , general; including training, pedagogy, didactics [and education systems] Impact factor: 1.755, year: 2016

  3. Local chatter or international buzz? Language differences on posts about Zika research on Twitter and Facebook.

    Directory of Open Access Journals (Sweden)

    Germana Barata

    Full Text Available When the Zika virus outbreak became a global health emergency in early 2016, the scientific community responded with an increased output of Zika-related research. This upsurge in research naturally made its way into academic journals along with editorials, news, and reports. However, it is not yet known how or whether these scholarly communications were distributed to the populations most affected by Zika.To understand how scientific outputs about Zika reached global and local audiences, we collected Tweets and Facebook posts that linked to Zika-related research in the first six months of 2016. Using a language detection algorithm, we found that up to 90% of Twitter and 76% of Facebook posts are in English. However, when none of the authors of the scholarly article are from English-speaking countries, posts on both social media are less likely to be in English. The effect is most pronounced on Facebook, where the likelihood of posting in English is between 11 and 16% lower when none of the authors are from English-speaking countries, as compared to when some or all are. Similarly, posts about papers written with a Brazilian author are 13% more likely to be in Portuguese on Facebook than when made on Twitter.Our main conclusion is that scholarly communication on Twitter and Facebook of Zika-related research is dominated by English, despite Brazil being the epicenter of the Zika epidemic. This result suggests that scholarly findings about the Zika virus are unlikely to be distributed directly to relevant populations through these popular online mediums. Nevertheless, there are differences between platforms. Compared to Twitter, scholarly communication on Facebook is more likely to be in the language of an author's country. The Zika outbreak provides a useful case-study for understanding how scientific outputs are communicated to relevant populations. Our results suggest that Facebook is a more effective channel than Twitter, if communication is

  4. Local chatter or international buzz? Language differences on posts about Zika research on Twitter and Facebook.

    Science.gov (United States)

    Barata, Germana; Shores, Kenneth; Alperin, Juan Pablo

    2018-01-01

    When the Zika virus outbreak became a global health emergency in early 2016, the scientific community responded with an increased output of Zika-related research. This upsurge in research naturally made its way into academic journals along with editorials, news, and reports. However, it is not yet known how or whether these scholarly communications were distributed to the populations most affected by Zika. To understand how scientific outputs about Zika reached global and local audiences, we collected Tweets and Facebook posts that linked to Zika-related research in the first six months of 2016. Using a language detection algorithm, we found that up to 90% of Twitter and 76% of Facebook posts are in English. However, when none of the authors of the scholarly article are from English-speaking countries, posts on both social media are less likely to be in English. The effect is most pronounced on Facebook, where the likelihood of posting in English is between 11 and 16% lower when none of the authors are from English-speaking countries, as compared to when some or all are. Similarly, posts about papers written with a Brazilian author are 13% more likely to be in Portuguese on Facebook than when made on Twitter. Our main conclusion is that scholarly communication on Twitter and Facebook of Zika-related research is dominated by English, despite Brazil being the epicenter of the Zika epidemic. This result suggests that scholarly findings about the Zika virus are unlikely to be distributed directly to relevant populations through these popular online mediums. Nevertheless, there are differences between platforms. Compared to Twitter, scholarly communication on Facebook is more likely to be in the language of an author's country. The Zika outbreak provides a useful case-study for understanding how scientific outputs are communicated to relevant populations. Our results suggest that Facebook is a more effective channel than Twitter, if communication is desired to be in the

  5. COMMUNICATIONS

    CERN Multimedia

    L. Taylor and D. Barney

    2010-01-01

    CMS Centres, Outreach and the 7 TeV Media Event The new CMS Communications group is now established and is addressing three areas that are critical to CMS as it enters the physics operations phase: - Communications Infrastructure, including almost 50 CMS Centres Worldwide, videoconferencing systems, and CERN meeting rooms - Information systems, including the internal and external Web sites as well as the document preparation and management systems - Outreach and Education activities, including working with print, radio and TV media, visits to CMS, and exhibitions. The group has been active in many areas, with the highest priority being accorded to needs of CMS operations and preparations for the major media event planned for 7 TeV collisions. Unfortunately the CMS Centre@CERN suffered a major setback when, on 21st December, a cooling water pipe froze and burst on the floor above the CMS Centre main room. Water poured through the ceiling, flooding the floor and soaking some of the consoles, before e...

  6. COMMUNICATIONS

    CERN Multimedia

    A. Petrilli

    2013-01-01

    The organisation of the Open Days at the end of September was the single biggest effort of the CMS Communications Group this year. We would like to thank all volunteers for their hard work to show our Point 5 facilities and explain science and technology to the general public. During two days more than 5,000 people visited the CMS detector underground and profited from the surface activities, which included an exhibition on CMS, a workshop on superconductivity, and an activity for our younger visitors involving wooden Kapla blocks. The Communications Group took advantage of the preparations to produce new CMS posters that can be reused at other venues. Event display images have been produced not just for this occasion but also for other exhibits, education purposes, publications etc. During the Open Days, Gilles Jobin, 2012 winner of CERN Collide@CERN prize, performed his Quantum show in Point 5, with the light installation of German artist Julius von Bismarck. Image 3: CERN Open Days at CMS wel...

  7. Sensor-Based Inspection of the Formation Accuracy in Ultra-Precision Grinding (UPG) of Aspheric Surface Considering the Chatter Vibration

    Science.gov (United States)

    Lei, Yao; Bai, Yue; Xu, Zhijun

    2018-06-01

    This paper proposes an experimental approach for monitoring and inspection of the formation accuracy in ultra-precision grinding (UPG) with respect to the chatter vibration. Two factors related to the grinding progress, the grinding speed of grinding wheel and spindle, and the oil pressure of the hydrostatic bearing are taken into account to determining the accuracy. In the meantime, a mathematical model of the radius deviation caused by the micro vibration is also established and applied in the experiments. The results show that the accuracy is sensitive to the vibration and the forming accuracy is much improved with proper processing parameters. It is found that the accuracy of aspheric surface can be less than 4 μm when the grinding speed is 1400 r/min and the wheel speed is 100 r/min with the oil pressure being 1.1 MPa.

  8. Sensor-Based Inspection of the Formation Accuracy in Ultra-Precision Grinding (UPG) of Aspheric Surface Considering the Chatter Vibration

    Science.gov (United States)

    Lei, Yao; Bai, Yue; Xu, Zhijun

    2018-03-01

    This paper proposes an experimental approach for monitoring and inspection of the formation accuracy in ultra-precision grinding (UPG) with respect to the chatter vibration. Two factors related to the grinding progress, the grinding speed of grinding wheel and spindle, and the oil pressure of the hydrostatic bearing are taken into account to determining the accuracy. In the meantime, a mathematical model of the radius deviation caused by the micro vibration is also established and applied in the experiments. The results show that the accuracy is sensitive to the vibration and the forming accuracy is much improved with proper processing parameters. It is found that the accuracy of aspheric surface can be less than 4 μm when the grinding speed is 1400 r/min and the wheel speed is 100 r/min with the oil pressure being 1.1 MPa.

  9. Using an adaptive fuzzy-logic system to optimize the performances and the reduction of chattering phenomenon in the control of induction motor

    Directory of Open Access Journals (Sweden)

    Barazane Linda

    2009-01-01

    Full Text Available Neural networks and fuzzy inference systems are becoming well recognized tools of designing an identifier/controller capable of perceiving the operating environment and imitating a human operator with high performance. Also, by combining these two features, more versatile and robust models, called 'neuro-fuzzy' architectures have been developed. The motivation behind the use of neuro-fuzzy approaches is based on the complexity of real life systems, ambiguities on sensory information or time-varying nature of the system under investigation. In this way, the present contribution concerns the application of neuro-fuzzy approach in order to perform the responses of the speed regulation and to reduce the chattering phenomenon introduced by sliding mode control, which is very harmful to the actuators in our case and may excite the unmodeled dynamics of the system. The type of the neuro-fuzzy system used here is called:' adaptive neuro fuzzy inference controller (ANFIS'. This neuro-fuzzy is destined to replace the speed fuzzy sliding mode controller after its training process. Simulation results reveal some very interesting features. .

  10. Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate

    NARCIS (Netherlands)

    van Zeijl, Leonie; Ponsioen, Bas; Giepmans, Ben N G; Ariaens, Aafke; Postma, Friso R; Várnai, Péter; Balla, Tamas; Divecha, Nullin; Jalink, Kees; Moolenaar, Wouter H

    2007-01-01

    Cell-cell communication through connexin43 (Cx43)-based gap junction channels is rapidly inhibited upon activation of various G protein coupled receptors; however, the mechanism is unknown. We show that Cx43-based cell-cell communication is inhibited by depletion of phosphatidylinositol

  11. The role of Rap1 in cell-cell junction formation

    NARCIS (Netherlands)

    Kooistra, M.R.H.

    2008-01-01

    Both epithelial and endothelial cells form cell-cell junctions at the cell-cell contacts to maintain tissue integrity. Proper regulation of cell-cell junctions is required for the organisation of the tissue and to prevent leakage of blood vessels. In endothelial cells, the cell-cell junctions are

  12. Structural basis of cell-cell adhesion by NCAM

    DEFF Research Database (Denmark)

    Kasper, C; Rasmussen, H; Kastrup, Jette Sandholm Jensen

    2000-01-01

    The neural cell adhesion molecule NCAM, a member of the immunoglobulin superfamily, mediates cell-cell recognition and adhesion via a homophilic interaction. NCAM plays a key role during development and regeneration of the nervous system and is involved in synaptic plasticity associated with memory...

  13. Secret handshakes: cell-cell interactions and cellular mimics.

    Science.gov (United States)

    Cohen, Daniel J; Nelson, W James

    2018-02-01

    Cell-cell junctions, acting as 'secret handshakes', mediate cell-cell interactions and make multicellularity possible. Work over the previous century illuminated key players comprising these junctions including the cadherin superfamily, nectins, CAMs, connexins, notch/delta, lectins, and eph/Ephrins. Recent work has focused on elucidating how interactions between these complex and often contradictory cues can ultimately give rise to large-scale organization in tissues. This effort, in turn, has enabled bioengineering advances such as cell-mimetic interfaces that allow us to better probe junction biology and to develop new biomaterials. This review details exciting, recent developments in these areas as well as providing both historical context and a discussion of some topical challenges and opportunities for the future. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Hepatitis C virus cell-cell transmission and resistance to direct-acting antiviral agents

    DEFF Research Database (Denmark)

    Xiao, Fei; Fofana, Isabel; Heydmann, Laura

    2014-01-01

    Hepatitis C virus (HCV) is transmitted between hepatocytes via classical cell entry but also uses direct cell-cell transfer to infect neighboring hepatocytes. Viral cell-cell transmission has been shown to play an important role in viral persistence allowing evasion from neutralizing antibodies....... In contrast, the role of HCV cell-cell transmission for antiviral resistance is unknown. Aiming to address this question we investigated the phenotype of HCV strains exhibiting resistance to direct-acting antivirals (DAAs) in state-of-the-art model systems for cell-cell transmission and spread. Using HCV...... genotype 2 as a model virus, we show that cell-cell transmission is the main route of viral spread of DAA-resistant HCV. Cell-cell transmission of DAA-resistant viruses results in viral persistence and thus hampers viral eradication. We also show that blocking cell-cell transmission using host...

  15. In silico characterization of cell-cell interactions using a cellular automata model of cell culture.

    Science.gov (United States)

    Kihara, Takanori; Kashitani, Kosuke; Miyake, Jun

    2017-07-14

    Cell proliferation is a key characteristic of eukaryotic cells. During cell proliferation, cells interact with each other. In this study, we developed a cellular automata model to estimate cell-cell interactions using experimentally obtained images of cultured cells. We used four types of cells; HeLa cells, human osteosarcoma (HOS) cells, rat mesenchymal stem cells (MSCs), and rat smooth muscle A7r5 cells. These cells were cultured and stained daily. The obtained cell images were binarized and clipped into squares containing about 10 4 cells. These cells showed characteristic cell proliferation patterns. The growth curves of these cells were generated from the cell proliferation images and we determined the doubling time of these cells from the growth curves. We developed a simple cellular automata system with an easily accessible graphical user interface. This system has five variable parameters, namely, initial cell number, doubling time, motility, cell-cell adhesion, and cell-cell contact inhibition (of proliferation). Within these parameters, we obtained initial cell numbers and doubling times experimentally. We set the motility at a constant value because the effect of the parameter for our simulation was restricted. Therefore, we simulated cell proliferation behavior with cell-cell adhesion and cell-cell contact inhibition as variables. By comparing growth curves and proliferation cell images, we succeeded in determining the cell-cell interaction properties of each cell. Simulated HeLa and HOS cells exhibited low cell-cell adhesion and weak cell-cell contact inhibition. Simulated MSCs exhibited high cell-cell adhesion and positive cell-cell contact inhibition. Simulated A7r5 cells exhibited low cell-cell adhesion and strong cell-cell contact inhibition. These simulated results correlated with the experimental growth curves and proliferation images. Our simulation approach is an easy method for evaluating the cell-cell interaction properties of cells.

  16. Communication without communication

    Directory of Open Access Journals (Sweden)

    Bratina Boris R.

    2017-01-01

    Full Text Available This paper analyses the necessary conditions for successful communication. It is well known that post-modernity, described as an era of control, produces only decentralized, imploded subjectivities, who are neither able to question their own being nor to relate one with another in authentic bonds of communication. Today, virtual communication has become an ultimate model of every possible communication whatsoever. The authors, therefore, pose the question of conditions for possibility of subjectivities who would be able and apt for authentic communication, wherein faith, fidelity, truth, and capability of keeping one's word occupy the central place.

  17. Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning.

    Science.gov (United States)

    Shaya, Oren; Binshtok, Udi; Hersch, Micha; Rivkin, Dmitri; Weinreb, Sheila; Amir-Zilberstein, Liat; Khamaisi, Bassma; Oppenheim, Olya; Desai, Ravi A; Goodyear, Richard J; Richardson, Guy P; Chen, Christopher S; Sprinzak, David

    2017-03-13

    During development, cells undergo dramatic changes in their morphology. By affecting contact geometry, these morphological changes could influence cellular communication. However, it has remained unclear whether and how signaling depends on contact geometry. This question is particularly relevant for Notch signaling, which coordinates neighboring cell fates through direct cell-cell signaling. Using micropatterning with a receptor trans-endocytosis assay, we show that signaling between pairs of cells correlates with their contact area. This relationship extends across contact diameters ranging from micrometers to tens of micrometers. Mathematical modeling predicts that dependence of signaling on contact area can bias cellular differentiation in Notch-mediated lateral inhibition processes, such that smaller cells are more likely to differentiate into signal-producing cells. Consistent with this prediction, analysis of developing chick inner ear revealed that ligand-producing hair cell precursors have smaller apical footprints than non-hair cells. Together, these results highlight the influence of cell morphology on fate determination processes. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Regulation of Arabidopsis Early Anther Development by Putative Cell-Cell Signaling Molecules and Transcriptional Regulators

    Institute of Scientific and Technical Information of China (English)

    Yu-Jin Sun; Carey LH Hord; Chang-Bin Chen; Hong Ma

    2007-01-01

    Anther development in flowering plants involves the formation of several cell types, including the tapetal and pollen mother cells. The use of genetic and molecular tools has led to the identification and characterization of genes that are critical for normal cell division and differentiation in Arabidopsis early anther development. We review here several recent studies on these genes, including the demonstration that the putative receptor protein kinases BAM1 and BAM2 together play essential roles in the control of early cell division and differentiation. In addition, we discuss the hypothesis that BAM1/2 may form a positive-negative feedback regulatory loop with a previously identified key regulator, SPOROCYTELESS (also called NOZZLE),to control the balance between sporogenous and somatic cell types in the anther. Furthermore, we summarize the isolation and functional analysis of the DYSFUNCTIONAL TAPETUM1 (DYT1) gene in promoting proper tapetal cell differentiation. Our finding that DYT1 encodes a putative transcription factor of the bHLH family, as well as relevant expression analyses, strongly supports a model that DYT1 serves as a critical link between upstream factors and downstream target genes that are critical for normal tapetum development and function. These studies, together with other recently published works, indicate that cell-cell communication and transcriptional control are key processes essential for cell fate specification in anther development.

  19. Integration of AI-2 Based Cell-Cell Signaling with Metabolic Cues in Escherichia coli.

    Directory of Open Access Journals (Sweden)

    Arindam Mitra

    Full Text Available The quorum sensing molecule Autoinducer-2 (AI-2 is generated as a byproduct of activated methyl cycle by the action of LuxS in Escherichia coli. AI-2 is synthesized, released and later internalized in a cell-density dependent manner. Here, by mutational analysis of the genes, uvrY and csrA, we describe a regulatory circuit of accumulation and uptake of AI-2. We constructed a single-copy chromosomal luxS-lacZ fusion in a luxS + merodiploid strain and evaluated its relative expression in uvrY and csrA mutants. At the entry of stationary phase, the expression of the fusion and AI-2 accumulation was positively regulated by uvrY and negatively regulated by csrA respectively. A deletion of csrA altered message stability of the luxS transcript and CsrA protein exhibited weak binding to 5' luxS regulatory region. DNA protein interaction and chromatin immunoprecipitation analysis confirmed direct interaction of UvrY with the luxS promoter. Additionally, reduced expression of the fusion in hfq deletion mutant suggested involvement of small RNA interactions in luxS regulation. In contrast, the expression of lsrA operon involved in AI-2 uptake, is negatively regulated by uvrY and positively by csrA in a cell-density dependent manner. The dual role of csrA in AI-2 synthesis and uptake suggested a regulatory crosstalk of cell signaling with carbon regulation in Escherichia coli. We found that the cAMP-CRP mediated catabolite repression of luxS expression was uvrY dependent. This study suggests that luxS expression is complex and regulated at the level of transcription and translation. The multifactorial regulation supports the notion that cell-cell communication requires interaction and integration of multiple metabolic signals.

  20. The role of adhesion energy in controlling cell?cell contacts

    OpenAIRE

    Ma?tre, Jean-L?on; Heisenberg, Carl-Philipp

    2011-01-01

    Recent advances in microscopy techniques and biophysical measurements have provided novel insight into the molecular, cellular and biophysical basis of cell adhesion. However, comparably little is known about a core element of cell?cell adhesion?the energy of adhesion at the cell?cell contact. In this review, we discuss approaches to understand the nature and regulation of adhesion energy, and propose strategies to determine adhesion energy between cells in vitro and in vivo.

  1. Well-Controlled Cell-Trapping Systems for Investigating Heterogeneous Cell-Cell Interactions.

    Science.gov (United States)

    Kamiya, Koki; Abe, Yuta; Inoue, Kosuke; Osaki, Toshihisa; Kawano, Ryuji; Miki, Norihisa; Takeuchi, Shoji

    2018-03-01

    Microfluidic systems have been developed for patterning single cells to study cell-cell interactions. However, patterning multiple types of cells to understand heterogeneous cell-cell interactions remains difficult. Here, it is aimed to develop a cell-trapping device to assemble multiple types of cells in the well-controlled order and morphology. This device mainly comprises a parylene sheet for assembling cells and a microcomb for controlling the cell-trapping area. The cell-trapping area is controlled by moving the parylene sheet on an SU-8 microcomb using tweezers. Gentle downward flow is used as a driving force for the cell-trapping. The assembly of cells on a parylene sheet with round and line-shaped apertures is demonstrated. The cell-cell contacts of the trapped cells are then investigated by direct cell-cell transfer of calcein via connexin nanopores. Finally, using the device with a system for controlling the cell-trapping area, three different types of cells in the well-controlled order are assembled. The correct cell order rate obtained using the device is 27.9%, which is higher than that obtained without the sliding parylene system (0.74%). Furthermore, the occurrence of cell-cell contact between the three cell types assembled is verified. This cell-patterning device will be a useful tool for investigating heterogeneous cell-cell interactions. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Communication among Oral Bacteria

    Science.gov (United States)

    Kolenbrander, Paul E.; Andersen, Roxanna N.; Blehert, David S.; Egland, Paul G.; Foster, Jamie S.; Palmer, Robert J.

    2002-01-01

    Human oral bacteria interact with their environment by attaching to surfaces and establishing mixed-species communities. As each bacterial cell attaches, it forms a new surface to which other cells can adhere. Adherence and community development are spatiotemporal; such order requires communication. The discovery of soluble signals, such as autoinducer-2, that may be exchanged within multispecies communities to convey information between organisms has emerged as a new research direction. Direct-contact signals, such as adhesins and receptors, that elicit changes in gene expression after cell-cell contact and biofilm growth are also an active research area. Considering that the majority of oral bacteria are organized in dense three-dimensional biofilms on teeth, confocal microscopy and fluorescently labeled probes provide valuable approaches for investigating the architecture of these organized communities in situ. Oral biofilms are readily accessible to microbiologists and are excellent model systems for studies of microbial communication. One attractive model system is a saliva-coated flowcell with oral bacterial biofilms growing on saliva as the sole nutrient source; an intergeneric mutualism is discussed. Several oral bacterial species are amenable to genetic manipulation for molecular characterization of communication both among bacteria and between bacteria and the host. A successful search for genes critical for mixed-species community organization will be accomplished only when it is conducted with mixed-species communities. PMID:12209001

  3. Unified communications

    OpenAIRE

    Kravos, Urban

    2011-01-01

    In the modern business world, communication are becoming more and more complex. As a solution to this problem unified communications occurred. Using a single communication approach unified communications are the integration of various communication technologies (eg, telephony, unified messaging, audio, video and web conferencing and collaboration tools). Unified Messaging, which represents only part of the unified communications means the integration of different non real time communication t...

  4. Diversity of Neuropeptide Cell-Cell Signaling Molecules Generated by Proteolytic Processing Revealed by Neuropeptidomics Mass Spectrometry

    Science.gov (United States)

    Hook, Vivian; Lietz, Christopher B.; Podvin, Sonia; Cajka, Tomas; Fiehn, Oliver

    2018-04-01

    Neuropeptides are short peptides in the range of 3-40 residues that are secreted for cell-cell communication in neuroendocrine systems. In the nervous system, neuropeptides comprise the largest group of neurotransmitters. In the endocrine system, neuropeptides function as peptide hormones to coordinate intercellular signaling among target physiological systems. The diversity of neuropeptide functions is defined by their distinct primary sequences, peptide lengths, proteolytic processing of pro-neuropeptide precursors, and covalent modifications. Global, untargeted neuropeptidomics mass spectrometry is advantageous for defining the structural features of the thousands to tens of thousands of neuropeptides present in biological systems. Defining neuropeptide structures is the basis for defining the proteolytic processing pathways that convert pro-neuropeptides into active peptides. Neuropeptidomics has revealed that processing of pro-neuropeptides occurs at paired basic residues sites, and at non-basic residue sites. Processing results in neuropeptides with known functions and generates novel peptides representing intervening peptide domains flanked by dibasic residue processing sites, identified by neuropeptidomics. While very short peptide products of 2-4 residues are predicted from pro-neuropeptide dibasic processing sites, such peptides have not been readily identified; therefore, it will be logical to utilize metabolomics to identify very short peptides with neuropeptidomics in future studies. Proteolytic processing is accompanied by covalent post-translational modifications (PTMs) of neuropeptides comprising C-terminal amidation, N-terminal pyroglutamate, disulfide bonds, phosphorylation, sulfation, acetylation, glycosylation, and others. Neuropeptidomics can define PTM features of neuropeptides. In summary, neuropeptidomics for untargeted, global analyses of neuropeptides is essential for elucidation of proteases that generate diverse neuropeptides for cell-cell

  5. Diversity of Neuropeptide Cell-Cell Signaling Molecules Generated by Proteolytic Processing Revealed by Neuropeptidomics Mass Spectrometry

    Science.gov (United States)

    Hook, Vivian; Lietz, Christopher B.; Podvin, Sonia; Cajka, Tomas; Fiehn, Oliver

    2018-05-01

    Neuropeptides are short peptides in the range of 3-40 residues that are secreted for cell-cell communication in neuroendocrine systems. In the nervous system, neuropeptides comprise the largest group of neurotransmitters. In the endocrine system, neuropeptides function as peptide hormones to coordinate intercellular signaling among target physiological systems. The diversity of neuropeptide functions is defined by their distinct primary sequences, peptide lengths, proteolytic processing of pro-neuropeptide precursors, and covalent modifications. Global, untargeted neuropeptidomics mass spectrometry is advantageous for defining the structural features of the thousands to tens of thousands of neuropeptides present in biological systems. Defining neuropeptide structures is the basis for defining the proteolytic processing pathways that convert pro-neuropeptides into active peptides. Neuropeptidomics has revealed that processing of pro-neuropeptides occurs at paired basic residues sites, and at non-basic residue sites. Processing results in neuropeptides with known functions and generates novel peptides representing intervening peptide domains flanked by dibasic residue processing sites, identified by neuropeptidomics. While very short peptide products of 2-4 residues are predicted from pro-neuropeptide dibasic processing sites, such peptides have not been readily identified; therefore, it will be logical to utilize metabolomics to identify very short peptides with neuropeptidomics in future studies. Proteolytic processing is accompanied by covalent post-translational modifications (PTMs) of neuropeptides comprising C-terminal amidation, N-terminal pyroglutamate, disulfide bonds, phosphorylation, sulfation, acetylation, glycosylation, and others. Neuropeptidomics can define PTM features of neuropeptides. In summary, neuropeptidomics for untargeted, global analyses of neuropeptides is essential for elucidation of proteases that generate diverse neuropeptides for cell-cell

  6. Communications article

    KAUST Repository

    Fariborzi, Hossein

    2017-01-01

    Seamless, covert communications using a communications system integrated or incorporated within an article of clothing is described. In one embodiment, the communications system is integrated or incorporated into a shoe insole and includes a haptic

  7. Emergency Communication

    Science.gov (United States)

    : Environmental Documents, Reports LANL Home Calendar Search Contacts Resources » Emergency Communication Emergency Communication Stay informed of emergencies, weather delays, closures, other alerts. Find links to

  8. Tactile Communications

    Data.gov (United States)

    National Aeronautics and Space Administration — Communication with the crew is vital and must be maintained regardless of environmental conditions and crew activity. Current spacecraft communication systems depend...

  9. Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.

    Science.gov (United States)

    McCoy, Laura E; Groppelli, Elisabetta; Blanchetot, Christophe; de Haard, Hans; Verrips, Theo; Rutten, Lucy; Weiss, Robin A; Jolly, Clare

    2014-10-02

    Direct cell-cell spread of HIV-1 is a very efficient mode of viral dissemination, with increasing evidence suggesting that it may pose a considerable challenge to controlling viral replication in vivo. Much current vaccine research involves the study of broadly neutralising antibodies (bNabs) that arise during natural infection with the aims of eliciting such antibodies by vaccination or incorporating them into novel therapeutics. However, whether cell-cell spread of HIV-1 can be effectively targeted by bNabs remains unclear, and there is much interest in identifying antibodies capable of efficiently neutralising virus transmitted by cell-cell contact. In this study we have tested a panel of bNAbs for inhibition of cell-cell spread, including some not previously evaluated for inhibition of this mode of HIV-1 transmission. We found that three CD4 binding site antibodies, one from an immunised llama (J3) and two isolated from HIV-1-positive patients (VRC01 and HJ16) neutralised cell-cell spread between T cells, while antibodies specific for glycan moieties (2G12, PG9, PG16) and the MPER (2F5) displayed variable efficacy. Notably, while J3 displayed a high level of potency during cell-cell spread we found that the small size of the llama heavy chain-only variable region (VHH) J3 is not required for efficient neutralisation since recombinant J3 containing a full-length human heavy chain Fc domain was significantly more potent. J3 and J3-Fc also neutralised cell-cell spread of HIV-1 from primary macrophages to CD4+ T cells. In conclusion, while bNabs display variable efficacy at preventing cell-cell spread of HIV-1, we find that some CD4 binding site antibodies can inhibit this mode of HIV-1 dissemination and identify the recently described llama antibody J3 as a particularly potent inhibitor. Effective neutralisation of cell-cell spread between physiologically relevant cell types by J3 and J3-Fc supports the development of VHH J3 nanobodies for therapeutic or

  10. Embryonic cell-cell adhesion: a key player in collective neural crest migration.

    Science.gov (United States)

    Barriga, Elias H; Mayor, Roberto

    2015-01-01

    Cell migration is essential for morphogenesis, adult tissue remodeling, wound healing, and cancer cell migration. Cells can migrate as individuals or groups. When cells migrate in groups, cell-cell interactions are crucial in order to promote the coordinated behavior, essential for collective migration. Interestingly, recent evidence has shown that cell-cell interactions are also important for establishing and maintaining the directionality of these migratory events. We focus on neural crest cells, as they possess extraordinary migratory capabilities that allow them to migrate and colonize tissues all over the embryo. Neural crest cells undergo an epithelial-to-mesenchymal transition at the same time than perform directional collective migration. Cell-cell adhesion has been shown to be an important source of planar cell polarity and cell coordination during collective movement. We also review molecular mechanisms underlying cadherin turnover, showing how the modulation and dynamics of cell-cell adhesions are crucial in order to maintain tissue integrity and collective migration in vivo. We conclude that cell-cell adhesion during embryo development cannot be considered as simple passive resistance to force, but rather participates in signaling events that determine important cell behaviors required for cell migration. © 2015 Elsevier Inc. All rights reserved.

  11. Communications article

    KAUST Repository

    Fariborzi, Hossein

    2017-07-20

    Seamless, covert communications using a communications system integrated or incorporated within an article of clothing is described. In one embodiment, the communications system is integrated or incorporated into a shoe insole and includes a haptic feedback mechanism, a communications module, a flexible pressure sensor, and a battery. The communications module includes a wireless communications module for wireless communications, a wired interface for wired communications, a microcontroller, and a battery charge controller. The flexible pressure sensor can be actuated by an individual\\'s toe, for example, and communication between two communications nodes can be achieved using coded signals sent by individuals using a combination of long and short presses on the pressure sensor. In response to the presses, wireless communications modules can transmit and receive coded signals based on the presses.

  12. APC senses cell-cell contacts and moves to the nucleus upon their disruption.

    Science.gov (United States)

    Brocardo, M G; Bianchini, M; Radrizzani, M; Reyes, G B; Dugour, A V; Taminelli, G L; Gonzalez Solveyra, C; Santa-Coloma, T A

    2001-06-22

    The adenomatous polyposis coli (APC) tumor suppressor protein is involved in the Wnt/wingless pathway, modulating beta-catenin activity. We report the development of a highly specific, chemically synthesized oligobody (oligonucleotide-based synthetic antibody), directed against the N-terminal region of APC. Using this reagent, we found that within 16 h of disrupting HT-29 cell-cell contacts by harvesting cells with trypsin/EDTA treatment and replating, APC was translocated from the cytoplasm to the nucleus. Five days after plating the cells, when the cells had returned to their normal confluent phenotype and cell-cell contacts were reestablished, APC returned to the cytoplasm. These results suggest that APC functions as part of a "sensor" system, and responds to the loss of cell-cell contacts by moving to the nucleus, and returning to the cytoplasm when the contacts are fully restored. Copyright 2001 Academic Press.

  13. Cell-extracellular matrix and cell-cell adhesion are linked by syndecan-4

    DEFF Research Database (Denmark)

    Pakideeri Karat, Sandeep Gopal; Multhaupt, Hinke A B; Pocock, Roger

    2017-01-01

    Cell-extracellular matrix (ECM) and cell-cell junctions that employ microfilaments are sites of tension. They are important for tissue repair, morphogenetic movements and can be emblematic of matrix contraction in fibrotic disease and the stroma of solid tumors. One cell surface receptor, syndecan...... calcium. While it is known that cell-ECM and cell-cell junctions may be linked, possible roles for syndecans in this process are not understood. Here we show that wild type primary fibroblasts and those lacking syndecan-4 utilize different cadherins in their adherens junctions and that tension is a major...... factor in this differential response. This corresponds to the reduced ability of fibroblasts lacking syndecan-4 to exert tension on the ECM and we now show that this may extend to reduced tension in cell-cell adhesion....

  14. Strategizing Communication

    DEFF Research Database (Denmark)

    Gulbrandsen, Ib Tunby; Just, Sine Nørholm

    beyond, but not past instrumental, rational plans in order to become better able to understand and manage the concrete, incremental practices and contexts in which communication becomes strategic. Thus, we argue that although strategic communicators do (and should) make plans, a plan in itself does...... of the specific communicative disciplines and practices employed by the organization and/or its individual members, be they marketing, public relations, corporate communication, branding, public affairs or social advocacy. In all cases, strategic communicators do well to focus more on the process of communicating...... for understanding and managing strategic communication processes....

  15. CSR communication

    DEFF Research Database (Denmark)

    Golob, Ursa; Podnar, Klement; Elving, Wim

    2013-01-01

    Purpose – This paper aims to introduce the special issue on CSR communication attached to the First International CSR Communication Conference held in Amsterdam in October 2011. The aim of the introduction is also to review CSR communication papers published in scholarly journals in order to make...... a summary of the state of CSR communication knowledge. Design/methodology/approach – The existing literature on CSR communication was approached via systematic review. with a combination of conventional and summative qualitative content analysis. The final dataset contained 90 papers from two main business...... communications. The most important outlets for CSR communication-related topics are Journal of Business Ethics and Corporate Communications: An International Journal. Originality/value – This paper represents the first attempt to perform a systematic and comprehensive overview of CSR communication papers...

  16. Scientific communication

    Directory of Open Access Journals (Sweden)

    Aleksander Kobylarek

    2017-09-01

    Full Text Available The article tackles the problem of models of communication in science. The formal division of communication processes into oral and written does not resolve the problem of attitude. The author defines successful communication as a win-win game, based on the respect and equality of the partners, regardless of their position in the world of science. The core characteristics of the process of scientific communication are indicated , such as openness, fairness, support, and creation. The task of creating the right atmosphere for science communication belongs to moderators, who should not allow privilege and differentiation of position to affect scientific communication processes.

  17. Rho GTPase activity modulates paramyxovirus fusion protein-mediated cell-cell fusion

    International Nuclear Information System (INIS)

    Schowalter, Rachel M.; Wurth, Mark A.; Aguilar, Hector C.; Lee, Benhur; Moncman, Carole L.; McCann, Richard O.; Dutch, Rebecca Ellis

    2006-01-01

    The paramyxovirus fusion protein (F) promotes fusion of the viral envelope with the plasma membrane of target cells as well as cell-cell fusion. The plasma membrane is closely associated with the actin cytoskeleton, but the role of actin dynamics in paramyxovirus F-mediated membrane fusion is unclear. We examined cell-cell fusion promoted by two different paramyxovirus F proteins in three cell types in the presence of constitutively active Rho family GTPases, major cellular coordinators of actin dynamics. Reporter gene and syncytia assays demonstrated that expression of either Rac1 V12 or Cdc42 V12 could increase cell-cell fusion promoted by the Hendra or SV5 glycoproteins, though the effect was dependent on the cell type expressing the viral glycoproteins. In contrast, RhoA L63 decreased cell-cell fusion promoted by Hendra glycoproteins but had little affect on SV5 F-mediated fusion. Also, data suggested that GTPase activation in the viral glycoprotein-containing cell was primarily responsible for changes in fusion. Additionally, we found that activated Cdc42 promoted nuclear rearrangement in syncytia

  18. Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions.

    Science.gov (United States)

    Kaji, Hirokazu; Camci-Unal, Gulden; Langer, Robert; Khademhosseini, Ali

    2011-03-01

    Inside the body, cells lie in direct contact or in close proximity to other cell types in a tightly controlled architecture that often regulates the resulting tissue function. Therefore, tissue engineering constructs that aim to reproduce the architecture and the geometry of tissues will benefit from methods of controlling cell-cell interactions with microscale resolution. We discuss the use of microfabrication technologies for generating patterned co-cultures. In addition, we categorize patterned co-culture systems by cell type and discuss the implications of regulating cell-cell interactions in the resulting biological function of the tissues. Patterned co-cultures are a useful tool for fabricating tissue engineered constructs and for studying cell-cell interactions in vitro, because they can be used to control the degree of homotypic and heterotypic cell-cell contact. In addition, this approach can be manipulated to elucidate important factors involved in cell-matrix interactions. Patterned co-culture strategies hold significant potential to develop biomimetic structures for tissue engineering. It is expected that they would create opportunities to develop artificial tissues in the future. This article is part of a Special Issue entitled Nanotechnologies - Emerging Applications in Biomedicine. 2010 Elsevier B.V. All rights reserved.

  19. Regulation of cell cycle progression by cell-cell and cell-matrix forces

    NARCIS (Netherlands)

    Uroz, Marina; Wistorf, Sabrina; Serra-Picamal, Xavier; Conte, Vito; Sales-Pardo, Marta; Roca-Cusachs, Pere; Guimerà, Roger; Trepat, Xavier

    2018-01-01

    It has long been proposed that the cell cycle is regulated by physical forces at the cell-cell and cell-extracellular matrix (ECM) interfaces 1-12 . However, the evolution of these forces during the cycle has never been measured in a tissue, and whether this evolution affects cell cycle progression

  20. Data communications

    International Nuclear Information System (INIS)

    Preckshot, G.G.

    1993-08-01

    The purpose of this paper is to recommend regulatory guidance for reviewers examining computer communication systems used in nuclear power plants. The recommendations cover three areas important to these communications systems: system design, communication protocols, and communication media. The first area, system design, considers three aspects of system design--questions about architecture, specific risky design elements or omissions to look for in designs being reviewed, and recommendations for multiplexed data communication systems used in safety systems. The second area reviews pertinent aspects of communication protocol design and makes recommendations for newly designed protocols or the selection of existing protocols for safety system, information display, and non-safety control system use. The third area covers communication media selection, which differs significantly from traditional wire and cable. The recommendations for communication media extend or enhance the concerns of published IEEE standards about three subjects: data rate, imported hazards and maintainability

  1. THE CHATTERING WAGTAILS OF MIKUYU PRISON Anthony ...

    African Journals Online (AJOL)

    postgraduate work and returned home just in time to witness the beginning of a reign of ... Another piece, 'The Haggling Old Woman at Balaka,' beautifully illustrates .... The title is based on the poet's chance visit to the maternity wing of Zomba.

  2. Communication, Communication, Communication! Growth through Laboratory Instructing

    Science.gov (United States)

    Peterson, Jamie J.; DeAngelo, Samantha; Mack, Nancy; Thompson, Claudia; Cooper, Jennifer; Sesma, Arturo, Jr.

    2014-01-01

    This study examined gains undergraduate students made in their communication and collaboration skills when they served as peer teachers, i.e., laboratory instructors (LIs), for a General Psychology laboratory. Self-ratings of communication and collaboration skills were completed before and after teaching the laboratory. When compared to before the…

  3. Participatory Communication

    DEFF Research Database (Denmark)

    Tufte, Thomas

    This user guide on participatory communication aims to answer the following questions: What do we mean when we say participatory communication? What are the practical implications of working with participatory communication strategies in development and social change processes? What practical exp......, tools, and experiences on how to implement participatory communications strategies. It is targeted toward government officials, World Bank staff, develompent workers in the field, and civil society....

  4. Local cell metrics: a novel method for analysis of cell-cell interactions.

    Science.gov (United States)

    Su, Jing; Zapata, Pedro J; Chen, Chien-Chiang; Meredith, J Carson

    2009-10-23

    The regulation of many cell functions is inherently linked to cell-cell contact interactions. However, effects of contact interactions among adherent cells can be difficult to detect with global summary statistics due to the localized nature and noise inherent to cell-cell interactions. The lack of informatics approaches specific for detecting cell-cell interactions is a limitation in the analysis of large sets of cell image data, including traditional and combinatorial or high-throughput studies. Here we introduce a novel histogram-based data analysis strategy, termed local cell metrics (LCMs), which addresses this shortcoming. The new LCM method is demonstrated via a study of contact inhibition of proliferation of MC3T3-E1 osteoblasts. We describe how LCMs can be used to quantify the local environment of cells and how LCMs are decomposed mathematically into metrics specific to each cell type in a culture, e.g., differently-labelled cells in fluorescence imaging. Using this approach, a quantitative, probabilistic description of the contact inhibition effects in MC3T3-E1 cultures has been achieved. We also show how LCMs are related to the naïve Bayes model. Namely, LCMs are Bayes class-conditional probability functions, suggesting their use for data mining and classification. LCMs are successful in robust detection of cell contact inhibition in situations where conventional global statistics fail to do so. The noise due to the random features of cell behavior was suppressed significantly as a result of the focus on local distances, providing sensitive detection of cell-cell contact effects. The methodology can be extended to any quantifiable feature that can be obtained from imaging of cell cultures or tissue samples, including optical, fluorescent, and confocal microscopy. This approach may prove useful in interpreting culture and histological data in fields where cell-cell interactions play a critical role in determining cell fate, e.g., cancer, developmental

  5. Cell division orientation is coupled to cell-cell adhesion by the E-cadherin/LGN complex

    NARCIS (Netherlands)

    Gloerich, Martijn; Bianchini, Julie M.; Siemers, Kathleen A.; Cohen, Daniel J.; Nelson, W. James

    2017-01-01

    Both cell-cell adhesion and oriented cell division play prominent roles in establishing tissue architecture, but it is unclear how they might be coordinated. Here, we demonstrate that the cell-cell adhesion protein E-cadherin functions as an instructive cue for cell division orientation. This is

  6. The requirements for herpes simplex virus type 1 cell-cell spread via nectin-1 parallel those for virus entry.

    Science.gov (United States)

    Even, Deborah L; Henley, Allison M; Geraghty, Robert J

    2006-08-01

    Herpes simplex virus type 1 (HSV-1) spreads from an infected cell to an uninfected cell by virus entry, virus-induced cell fusion, and cell-cell spread. The three forms of virus spread require the viral proteins gB, gD, and gH-gL, as well as a cellular gD receptor. The mutual requirement for the fusion glycoproteins and gD receptor suggests that virus entry, cell fusion, and cell-cell spread occur by a similar mechanism. The goals of this study were to examine the role of the nectin-1alpha transmembrane domain and cytoplasmic tail in cell-cell spread and to obtain a better understanding of the receptor-dependent events occurring at the plasma membrane during cell-cell spread. We determined that an intact nectin-1alpha V-like domain was required for cell-cell spread, while a membrane-spanning domain and cytoplasmic tail were not. Chimeric forms of nectin-1 that were non-functional for virus entry did not mediate cell-cell spread regardless of whether they could mediate cell fusion. Also, cell-cell spread of syncytial isolates was dependent upon nectin-1alpha expression and occurred through a nectin-1-dependent mechanism. Taken together, our results indicate that nectin-1-dependent events occurring at the plasma membrane during cell-cell spread were equivalent to those for virus entry.

  7. Cultural Communications.

    Science.gov (United States)

    Armas, Jose

    It is too often taken for granted that the communication process with culturally different children takes place as readily as it might with children from Anglo cultures. Most teachers receive training in verbal and formal communication skills; children come to school with nonverbal and informal communication skills. This initially can create…

  8. Stereotypes Communication

    Science.gov (United States)

    Zhang, Shuli; Deng, Dongyuan

    2009-01-01

    We live in a world, which is becoming a Global Village in which information and communication attract people's attention more than ever before. Our desire to communicate with strangers and our relationships with them depend on the degree to which we are effective in communicating with them. There are so many factors restricting or improving…

  9. Communication Speaks

    Science.gov (United States)

    Kinman, Robin Lynn

    2010-01-01

    When the author recently turned her attention to the National Council of Teachers of Mathematics (NCTM) "Principles and Standards," she was startled to see communication as key. She adjusted her teaching to meet the NCTM Communication Standard and promote communication in her classroom by providing a safe environment, developing discourse and…

  10. Ripple Communication.

    Science.gov (United States)

    Wilcox, R. Stimson

    1980-01-01

    Discusses how surface-dwelling animals use the water surface as a mode of communication by making ripple signals while they swim about. Provides information about surfaces and surface waves, ripple communication in water striders, ripple signal characteristics, sensing and orienting, other modes of communication, and evolution of ripple…

  11. Communication Acoustics

    DEFF Research Database (Denmark)

    Blauert, Jens

    Communication Acoustics deals with the fundamentals of those areas of acoustics which are related to modern communication technologies. Due to the advent of digital signal processing and recording in acoustics, these areas have enjoyed an enormous upswing during the last 4 decades. The book...... the book a source of valuable information for those who want to improve or refresh their knowledge in the field of communication acoustics - and to work their way deeper into it. Due to its interdisciplinary character Communication Acoustics is bound to attract readers from many different areas, such as......: acoustics, cognitive science, speech science, and communication technology....

  12. Data communications

    International Nuclear Information System (INIS)

    Ann, Byeong Ho; Baek, Jeong Hun

    1998-01-01

    The contents of this book are notion of data communications : summary on data communication, data transmission, data communications system, data transmission technology, data conversion, data link control and control over error of data transmission and exchange of data communications network in the first part, computer communications network architecture : data communications architecture, OSI model, lower layer of OSI model, upper layer of OSI model and distributed surroundings in the second part, data information networking : LAN, FDDI, 100 Base T, DQDB and Frame Relay in the third part, Public Network : PSDN, N-ISDN, B-ISDN in the fourth part, internet and PC communication : emulator program, Binary file, BBS, E-mail service and user on-line service in the last part.

  13. Electrocortical activity associated with subjective communication with the deceased

    Directory of Open Access Journals (Sweden)

    Arnaud eDelorme

    2013-11-01

    Full Text Available During advanced meditative practices, unusual perceptions can arise including the sense of receiving information about unknown people who are deceased (discarnates. The reported experience of initiating mental communication with the deceased, may involve a state of consciousness similar to that achieved in contemplative meditation practices. As with meditation, this mental state involves calming mental chatter and becoming receptive to subtle feelings and sensations. Psychometric and brain electrophysiology data were collected from six individuals who had previously reported accurate information about discarnates under double-blind conditions. Each experimental participant performed two tasks with eyes closed. In the first task, the participant was given only the first name of a discarnate and asked 25 questions. After each question, the participant was asked to silently perceive information relevant to the question for 20 seconds so clean electro-encephalography data could be collected and then respond verbally. Responses were then transcribed and scored by individuals who knew the discarnates. Of the six participants, two could not be evaluated, and the four other participants scored higher than chance level (p<0.03 for 3 of the 4 participants. The correlation between accuracy and brain activity was significant in frontal theta for one participant (p < 0.01. In the second task, participants were asked to experience four mental states, each repeated three times for one minute: (1 Thinking about a known living person, (2 Listening to a biography, (3 Thinking about an imaginary person, and (4 Interacting mentally with a known discarnate. Statistically significant differences in electrocortical activity among the four conditions were obtained in all six participants, primarily at gamma frequencies. These differences suggest that the impression of communicating with the deceased may be a distinct mental state distinct from ordinary thinking or

  14. Communication theory

    DEFF Research Database (Denmark)

    Stein, Irene F.; Stelter, Reinhard

    2011-01-01

    Communication theory covers a wide variety of theories related to the communication process (Littlejohn, 1999). Communication is not simply an exchange of information, in which we have a sender and a receiver. This very technical concept of communication is clearly outdated; a human being...... is not a data processing device. In this chapter, communication is understood as a process of shared meaning-making (Bruner, 1990). Human beings interpret their environment, other people, and themselves on the basis of their dynamic interaction with the surrounding world. Meaning is essential because people...... ascribe specific meanings to their experiences, their actions in life or work, and their interactions. Meaning is reshaped, adapted, and transformed in every communication encounter. Furthermore, meaning is cocreated in dialogues or in communities of practice, such as in teams at a workplace or in school...

  15. Cell-cell transmission of VSV-G pseudotyped lentivector particles.

    Directory of Open Access Journals (Sweden)

    Amy M Skinner

    Full Text Available Many replicating viruses, including HIV-1 and HTLV-1, are efficiently transmitted from the cell surface of actively infected cells upon contact with bystander cells. In a previous study, we reported the prolonged cell surface retention of VSV-G replication-deficient pseudotyped lentivector prior to endocytic entry. However, the competing kinetics of cell surface versus dissociation, neutralization or direct transfer to other cells have received comparatively little attention. Here we demonstrate that the relative efficiency of cell-cell surface transmission can outpace "cell-free" transduction at limiting vector input. This coincides with the prolonged half-life of cell bound vector but occurs, unlike HTLV-1, without evidence for particle aggregation. These studies suggest that cell-surface attachment stabilizes particles and alters neutralization kinetics. Our experiments provide novel insight into the underexplored cell-cell transmission of pseudotyped particles.

  16. Postcultural Communication?

    DEFF Research Database (Denmark)

    Jensen, Iben

    2015-01-01

    When we as scholars use the concept of intercultural communication in its classic definition, as communication between people with different cultural backgrounds, we perpetuate the notion that national differences influence communication more than other differences; in doing so, ethnic minorities...... is presented as a postcultural prism composed by practice theory (Schatzki 1996, Reckwitz 2002, Nicolini 2012, Kemmis 2012), Intersectionality (Brah, Phoenix, Collins Rahsack) and positioning theory (Harre & Langenhove 1998)....

  17. Local cell metrics: a novel method for analysis of cell-cell interactions

    Directory of Open Access Journals (Sweden)

    Chen Chien-Chiang

    2009-10-01

    Full Text Available Abstract Background The regulation of many cell functions is inherently linked to cell-cell contact interactions. However, effects of contact interactions among adherent cells can be difficult to detect with global summary statistics due to the localized nature and noise inherent to cell-cell interactions. The lack of informatics approaches specific for detecting cell-cell interactions is a limitation in the analysis of large sets of cell image data, including traditional and combinatorial or high-throughput studies. Here we introduce a novel histogram-based data analysis strategy, termed local cell metrics (LCMs, which addresses this shortcoming. Results The new LCM method is demonstrated via a study of contact inhibition of proliferation of MC3T3-E1 osteoblasts. We describe how LCMs can be used to quantify the local environment of cells and how LCMs are decomposed mathematically into metrics specific to each cell type in a culture, e.g., differently-labelled cells in fluorescence imaging. Using this approach, a quantitative, probabilistic description of the contact inhibition effects in MC3T3-E1 cultures has been achieved. We also show how LCMs are related to the naïve Bayes model. Namely, LCMs are Bayes class-conditional probability functions, suggesting their use for data mining and classification. Conclusion LCMs are successful in robust detection of cell contact inhibition in situations where conventional global statistics fail to do so. The noise due to the random features of cell behavior was suppressed significantly as a result of the focus on local distances, providing sensitive detection of cell-cell contact effects. The methodology can be extended to any quantifiable feature that can be obtained from imaging of cell cultures or tissue samples, including optical, fluorescent, and confocal microscopy. This approach may prove useful in interpreting culture and histological data in fields where cell-cell interactions play a critical

  18. Championship Communication

    Science.gov (United States)

    VanDerveer, Beth; Butterick, Betsy

    2017-01-01

    This article discusses team development and focuses specifically on championship communication and team-building activities. Team development takes time and the process typically occurs in stages. Regardless of the sport or what the competitive field may look like, communication is an often overlooked, yet vital element in cultivating a…

  19. Effective communication

    International Nuclear Information System (INIS)

    Kuntz, B.S.

    1989-01-01

    At the Waste Isolation Pilot Plant (WIPP) the responsibilities assigned to public affairs (PA) include communications to two main groups: institutional representatives and the general public. Research data indicates that these two populations perceive risk in different fashions. This paper discusses these distinct perceptions and how the communication programs at WIPP have been designed to accommodate these two differences

  20. Satellite Communications

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Satellite Communications. Arthur C Clarke wrote a seminal paper in 1945 in wireless world. Use three satellites in geo-synchronous orbit to enable intercontinental communications. System could be realised in '50 to 100 years'

  1. Science communication as political communication

    Science.gov (United States)

    Scheufele, Dietram A.

    2014-01-01

    Scientific debates in modern societies often blur the lines between the science that is being debated and the political, moral, and legal implications that come with its societal applications. This manuscript traces the origins of this phenomenon to professional norms within the scientific discipline and to the nature and complexities of modern science and offers an expanded model of science communication that takes into account the political contexts in which science communication takes place. In a second step, it explores what we know from empirical work in political communication, public opinion research, and communication research about the dynamics that determine how issues are debated and attitudes are formed in political environments. Finally, it discusses how and why it will be increasingly important for science communicators to draw from these different literatures to ensure that the voice of the scientific community is heard in the broader societal debates surrounding science. PMID:25225389

  2. Science communication as political communication.

    Science.gov (United States)

    Scheufele, Dietram A

    2014-09-16

    Scientific debates in modern societies often blur the lines between the science that is being debated and the political, moral, and legal implications that come with its societal applications. This manuscript traces the origins of this phenomenon to professional norms within the scientific discipline and to the nature and complexities of modern science and offers an expanded model of science communication that takes into account the political contexts in which science communication takes place. In a second step, it explores what we know from empirical work in political communication, public opinion research, and communication research about the dynamics that determine how issues are debated and attitudes are formed in political environments. Finally, it discusses how and why it will be increasingly important for science communicators to draw from these different literatures to ensure that the voice of the scientific community is heard in the broader societal debates surrounding science.

  3. Study of the time effect on the strength of cell-cell adhesion force by a novel nano-picker

    Energy Technology Data Exchange (ETDEWEB)

    Shen, Yajing, E-mail: shen@robo.mein.naogya-u.ac.jp [Dept. of Micro-Nano Systems Engineering, Nagoya University, Nagoya 464-8603 (Japan); Nakajima, Masahiro [Center for Micro-Nano Mechatronics, Nagoya University, Nagoya 464-8603 (Japan); Kojima, Seiji; Homma, Michio [Division of Biological Science, Nagoya University, Nagoya 464-8603 (Japan); Fukuda, Toshio [Dept. of Micro-Nano Systems Engineering, Nagoya University, Nagoya 464-8603 (Japan); Center for Micro-Nano Mechatronics, Nagoya University, Nagoya 464-8603 (Japan)

    2011-06-03

    Highlights: {yields} A nano-picker is developed for single cell adhesion force measurement. {yields} The adhesion of picker-cell has no influence to the cell-cell measurement result. {yields} Cell-cell adhesion force has a rise at the first few minutes and then becomes constant. -- Abstract: Cell's adhesion is important to cell's interaction and activates. In this paper, a novel method for cell-cell adhesion force measurement was proposed by using a nano-picker. The effect of the contact time on the cell-cell adhesion force was studied. The nano-picker was fabricated from an atomic force microscopy (AFM) cantilever by nano fabrication technique. The cell-cell adhesion force was measured based on the deflection of the nano-picker beam. The result suggests that the adhesion force between cells increased with the increasing of contact time at the first few minutes. After that, the force became constant. This measurement methodology was based on the nanorobotic manipulation system inside an environmental scanning electron microscope. It can realize both the observation and manipulation of a single cell at nanoscale. The quantitative and precise cell-cell adhesion force result can be obtained by this method. It would help us to understand the single cell interaction with time and would benefit the research in medical and biological fields potentially.

  4. Engineering amount of cell-cell contact demonstrates biphasic proliferative regulation through RhoA and the actin cytoskeleton

    International Nuclear Information System (INIS)

    Gray, Darren S.; Liu, Wendy F.; Shen, Colette J.; Bhadriraju, Kiran; Nelson, Celeste M.; Chen, Christopher S.

    2008-01-01

    Endothelial cell-cell contact via VE-cadherin plays an important role in regulating numerous cell functions, including proliferation. However, using different experimental approaches to manipulate cell-cell contact, investigators have observed both inhibition and stimulation of proliferation depending on the adhesive context. In this study, we used micropatterned wells combined with active positioning of cells by dielectrophoresis in order to investigate whether the number of contacting neighbors affected the proliferative response. Varying cell-cell contact resulted in a biphasic effect on proliferation; one contacting neighbor increased proliferation, while two or more neighboring cells partially inhibited this increase. We also observed that cell-cell contact increased the formation of actin stress fibers, and that expression of dominant negative RhoA (RhoN19) blocked the contact-mediated increase in stress fibers and proliferation. Furthermore, examination of heterotypic pairs of untreated cells in contact with RhoN19-expressing cells revealed that intracellular, but not intercellular, tension is required for the contact-mediated stimulation of proliferation. Moreover, engagement of VE-cadherin with cadherin-coated beads was sufficient to stimulate proliferation in the absence of actual cell-cell contact. In all, these results demonstrate that cell-cell contact signals through VE-cadherin, RhoA, and intracellular tension in the actin cytoskeleton to regulate proliferation

  5. Satellite Communications

    CERN Document Server

    Pelton, Joseph N

    2012-01-01

    The field of satellite communications represents the world's largest space industry. Those who are interested in space need to understand the fundamentals of satellite communications, its technology, operation, business, economic, and regulatory aspects. This book explains all this along with key insights into the field's future growth trends and current strategic challenges. Fundamentals of Satellite Communications is a concise book that gives all of the key facts and figures as well as a strategic view of where this dynamic industry is going. Author Joseph N. Pelton, PhD, former Dean of the International Space University and former Director of Strategic Policy at Intelstat, presents a r

  6. Short communication

    African Journals Online (AJOL)

    abp

    2017-09-04

    Sep 4, 2017 ... Face-to-face interviews were conducted using a standardized ... Short communication. Open Access ... clinic during the time of the study and were invited to participate in the study. .... consume them. This is another ...

  7. Brief communication

    Indian Academy of Sciences (India)

    2013-11-05

    Nov 5, 2013 ... Brief communication. Published ... showed longer FIDs in response to a human looking at them than to a human not looking at them (Burger et al. 1992). ..... Rivas JA and Burghardt GM 2001 Understanding sexual size dimor-.

  8. Brief communication

    Indian Academy of Sciences (India)

    2011-03-14

    Mar 14, 2011 ... 1Department of Crop, Soil and Environmental Sciences, 2Department of Horticulture, University of Arkansas, ... controlled by the soybean heat-shock promoter is an effective tool for conditional removal ... Brief communication ...

  9. COMMUNICATIONS GROUP

    CERN Multimedia

    L. Taylor

    2011-01-01

    The CMS Communications Group, established at the start of 2010, has been busy in all three areas of its responsibility: (1) Communications Infrastructure, (2) Information Systems, and (3) Outreach and Education. Communications Infrastructure There are now 55 CMS Centres worldwide that are well used by physicists working on remote CMS shifts, Computing operations, data quality monitoring, data analysis and outreach. The CMS Centre@CERN in Meyrin, is the centre of the CMS offline and computing operations, hosting dedicated analysis efforts such as during the CMS Heavy Ion lead-lead running. With a majority of CMS sub-detectors now operating in a “shifterless” mode, many monitoring operations are now routinely performed from there, rather than in the main Control Room at P5. The CMS Communications Group, CERN IT and the EVO team are providing excellent videoconferencing support for the rapidly-increasing number of CMS meetings. In parallel, CERN IT and ...

  10. PC communication

    International Nuclear Information System (INIS)

    Oh, Jae Cheol

    1992-03-01

    This text book is comprised of five charters, which is about PC communication for beginners who need to learn manners and how to use Ketel and PC serve. So it introduces first, conception of PC and precautions on using PC communication, second, preparation for PC communication with Modem, its program, install, kinds of protocol and how to use protocol, third directions of emulator of PC communication and super session, fourth, instruction of Ketel with join and access, basic command of Ketel, list of Ketel's menu, Ketel editor, service guide, directions of News service, Stock and bond service business and economic figures, exchange rate and interest rate, tax culture and leisure, Ketel BBS service and posting. The last part has a instruction of PC-serve about join, basic command of PC-serve, service guide and practical guideline.

  11. PC communication

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jae Cheol

    1992-03-15

    This text book is comprised of five charters, which is about PC communication for beginners who need to learn manners and how to use Ketel and PC serve. So it introduces first, conception of PC and precautions on using PC communication, second, preparation for PC communication with Modem, its program, install, kinds of protocol and how to use protocol, third directions of emulator of PC communication and super session, fourth, instruction of Ketel with join and access, basic command of Ketel, list of Ketel's menu, Ketel editor, service guide, directions of News service, Stock and bond service business and economic figures, exchange rate and interest rate, tax culture and leisure, Ketel BBS service and posting. The last part has a instruction of PC-serve about join, basic command of PC-serve, service guide and practical guideline.

  12. SHORT COMMUNICATION

    African Journals Online (AJOL)

    PROF P.T. KAYE

    . SHORT COMMUNICATION. Formation and Structural Analysis of Novel Dibornyl Ethers. Perry T. Kaye*, Andrew R. Duggan, Joseph M. Matjila, Warner E. Molema, and. Swarnam S. Ravindran. Department of Chemistry, Rhodes University, Grahamstown, ...

  13. Police Communications

    Science.gov (United States)

    1981-01-01

    Oklahoma City Police Department developed a computerized communications system, based on Johnson Space Center's (JSC's) 1960-mission control knowledge. JSC furnished information on lighting and other fatigue reducing measures, and provided specifications for equipment and design layouts. JSC also advised OCPD how to avoid communications bottlenecks associated with simultaneous handling of telephone, radio and inner-office transmissions. Oklahoma City saved money in reduced design and engineering costs by utilizing the already developed NASA technology.

  14. Antifragile Communications

    OpenAIRE

    Lichtman, Marc Louis

    2016-01-01

    Jamming is an ongoing threat that plagues wireless communications in contested areas. Unfortunately, jamming complexity and sophistication will continue to increase over time. The traditional approach to addressing the jamming threat is to harden radios, such that they sacrifice communications performance for more advanced jamming protection. To provide an escape from this trend, we investigate the previously unexplored area of jammer exploitation. This dissertation develops the concep...

  15. Aesthetic Communication

    DEFF Research Database (Denmark)

    Thyssen, Ole

    2012-01-01

    Based on Niklas Luhmann's systems theory, aesthetics is defined as a manner of reinforcing the connectivity, or Anschlusswert, of communication. Without changing the content, a message can be made more attractive, strengthening the receiver's willingness to be attentive and accepting. As communic......Based on Niklas Luhmann's systems theory, aesthetics is defined as a manner of reinforcing the connectivity, or Anschlusswert, of communication. Without changing the content, a message can be made more attractive, strengthening the receiver's willingness to be attentive and accepting....... As communication inevitably makes use of a sensuous medium, such as light or sound, all communication has an aesthetic dimension. In the 19th Century, an important distinction was made between pure and applied art, following Immanuel Kant's separation of theory of knowledge, moral theory and aesthetic theory....... Whereas pure art is produced in order to be observed, applied art has to fulfill practical purposes as well. Modern organizations, defined as systems of communication, may use art works to embellish and define themselves. But they inevitably use applied art as a practical tool in their normal...

  16. The contribution of cell-cell signaling and motility to bacterial biofilm formation

    DEFF Research Database (Denmark)

    Shrout, Joshua D; Tolker-Nielsen, Tim; Givskov, Michael

    2011-01-01

    Many bacteria grow attached to a surface as biofilms. Several factors dictate biofilm formation, including responses by the colonizing bacteria to their environment. Here we review how bacteria use cell-cell signaling (also called quorum sensing) and motility during biofilm formation. Specifically...... gene expression important to the production of polysaccharides, rhamnolipid, and other virulence factors. Surface motility affects the assembly and architecture of biofilms, and some aspects of motility are also influenced by quorum sensing. While some genes and their function are specific to P....... aeruginosa, many aspects of biofilm development can be used as a model system to understand how bacteria differentially colonize surfaces....

  17. The Visual Communication or Graphic Communication Dilemma

    Science.gov (United States)

    Fecik, John T.

    1975-01-01

    The author reviews the history of communication and communications technology, considers differences between "visual communication" and "graphic communication," and comments on "seeds of revolution" in the industry. He offers four components of an educational structure or organization titled "graphic…

  18. Communicating Science

    Science.gov (United States)

    Holland, G. J.; McCaffrey, M. S.; Kiehl, J. T.; Schmidt, C.

    2010-12-01

    We are in an era of rapidly changing communication media, which is driving a major evolution in the modes of communicating science. In the past, a mainstay of scientific communication in popular media was through science “translators”; science journalists and presenters. These have now nearly disappeared and are being replaced by widespread dissemination through, e.g., the internet, blogs, YouTube and journalists who often have little scientific background and sharp deadlines. Thus, scientists are required to assume increasing responsibility for translating their scientific findings and calibrating their communications to non-technical audiences, a task for which they are often ill prepared, especially when it comes to controversial societal issues such as tobacco, evolution, and most recently climate change (Oreskes and Conway 2010). Such issues have been politicized and hi-jacked by ideological belief systems to such an extent that constructive dialogue is often impossible. Many scientists are excellent communicators, to their peers. But this requires careful attention to detail and logical explanation, open acknowledgement of uncertainties, and dispassionate delivery. These qualities become liabilities when communicating to a non-scientific audience where entertainment, attention grabbing, 15 second sound bites, and self assuredness reign (e.g. Olson 2009). Here we report on a program initiated by NCAR and UCAR to develop new approaches to science communication and to equip present and future scientists with the requisite skills. If we start from a sound scientific finding with general scientific consensus, such as the warming of the planet by greenhouse gases, then the primary emphasis moves from the “science” to the “art” of communication. The art cannot have free reign, however, as there remains a strong requirement for objectivity, honesty, consistency, and above all a resistance to advocating particular policy positions. Targeting audience

  19. Adherens junction distribution mechanisms during cell-cell contact elongation in Drosophila.

    Directory of Open Access Journals (Sweden)

    Gabrielle Goldenberg

    Full Text Available During Drosophila gastrulation, amnioserosa (AS cells flatten and spread as an epithelial sheet. We used AS morphogenesis as a model to investigate how adherens junctions (AJs distribute along elongating cell-cell contacts in vivo. As the contacts elongated, total AJ protein levels increased along their length. However, genetically blocking this AJ addition indicated that it was not essential for maintaining AJ continuity. Implicating other remodeling mechanisms, AJ photobleaching revealed non-directional lateral mobility of AJs along the elongating contacts, as well as local AJ removal from the membranes. Actin stabilization with jasplakinolide reduced AJ redistribution, and live imaging of myosin II along elongating contacts revealed fragmented, expanding and contracting actomyosin networks, suggesting a mechanism for lateral AJ mobility. Actin stabilization also increased total AJ levels, suggesting an inhibition of AJ removal. Implicating AJ removal by endocytosis, clathrin endocytic machinery accumulated at AJs. However, dynamin disruption had no apparent effect on AJs, suggesting the involvement of redundant or dynamin-independent mechanisms. Overall, we propose that new synthesis, lateral diffusion, and endocytosis play overlapping roles to populate elongating cell-cell contacts with evenly distributed AJs in this in vivo system.

  20. Low Doses of Curcuma longa Modulates Cell Migration and Cell-Cell Adhesion.

    Science.gov (United States)

    de Campos, Paloma Santos; Matte, Bibiana Franzen; Diel, Leonardo Francisco; Jesus, Luciano Henrique; Bernardi, Lisiane; Alves, Alessandro Menna; Rados, Pantelis Varvaki; Lamers, Marcelo Lazzaron

    2017-09-01

    Cell invasion and metastasis are involved in clinical failures in cancer treatment, and both events require the acquisition of a migratory behavior by tumor cells. Curcumin is a promising natural product with anti-proliferative activity, but its effects on cell migration are still unclear. We evaluated the effects of curcumin on the proliferation, apoptosis, migration, and cell-cell adhesion of keratinocyte, oral squamous cell carcinoma (OSCC), and fibroblast cell lines, as well as in a xenograft model of OSCC. Curcumin (2 μM) decreased cell proliferation in cell lines with mesenchymal characteristics, while cell death was detected only at 50 μM. We observed that highly migratory cells showed a decrease on migration speed and directionality when treated with 2 or 5 μM of curcumin (50% and 40%, respectively, p curcumin dose dependently decreased cell-cell adhesion, especially on tumor-derived spheroids. Also, in a xenograft model with patient-derived OSCC cells, the administration of curcumin decreased tumor growth and aggressiveness when compared with untreated tumors, indicating the potential antitumor effect in oral cancer. These results suggest that lower doses of curcumin can influence several steps involved in tumorigenesis, including migration properties, suggesting a possible use in cancer therapy. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  1. Biomaterials that promote cell-cell interactions enhance the paracrine function of MSCs.

    Science.gov (United States)

    Qazi, Taimoor H; Mooney, David J; Duda, Georg N; Geissler, Sven

    2017-09-01

    Mesenchymal stromal cells (MSCs) secrete paracrine factors that play crucial roles during tissue regeneration. Whether this paracrine function is influenced by the properties of biomaterials in general, and those used for cell delivery in particular, largely remains unexplored. Here, we investigated if three-dimensional culture in distinct microenvironments - nanoporous hydrogels (mean pore size ∼5 nm) and macroporous scaffolds (mean pore size ∼120 μm) - affects the secretion pattern of MSCs, and consequently leads to differential paracrine effects on target progenitor cells such as myoblasts. We report that compared to MSCs encapsulated in hydrogels, scaffold seeded MSCs show an enhanced secretion profile and exert beneficial paracrine effects on various myoblast functions including migration and proliferation. Additionally, we show that the heightened paracrine effects of scaffold seeded cells can in part be attributed to N-cadherin mediated cell-cell interactions during culture. In hydrogels, this physical interaction between cells is prevented by the encapsulating matrix. Functionally blocking N-cadherin negatively affected the secretion profile and paracrine effects of MSCs on myoblasts, with stronger effects observed for scaffold seeded compared to hydrogel encapsulated cells. Together, these findings demonstrate that the therapeutic potency of MSCs can be enhanced by biomaterials that promote cell-cell interactions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Short-lived, transitory cell-cell interactions foster migration-dependent aggregation.

    Directory of Open Access Journals (Sweden)

    Melissa D Pope

    Full Text Available During embryonic development, motile cells aggregate into cohesive groups, which give rise to tissues and organs. The role of cell migration in regulating aggregation is unclear. The current paradigm for aggregation is based on an equilibrium model of differential cell adhesivity to neighboring cells versus the underlying substratum. In many biological contexts, however, dynamics is critical. Here, we provide evidence that multicellular aggregation dynamics involves both local adhesive interactions and transport by cell migration. Using time-lapse video microscopy, we quantified the duration of cell-cell contacts among migrating cells that collided and adhered to another cell. This lifetime of cell-cell interactions exhibited a monotonic decreasing dependence on substratum adhesivity. Parallel quantitative measurements of cell migration speed revealed that across the tested range of adhesive substrata, the mean time needed for cells to migrate and encounter another cell was greater than the mean adhesion lifetime, suggesting that aggregation dynamics may depend on cell motility instead of the local differential adhesivity of cells. Consistent with this hypothesis, aggregate size exhibited a biphasic dependence on substratum adhesivity, matching the trend we observed for cell migration speed. Our findings suggest a new role for cell motility, alongside differential adhesion, in regulating developmental aggregation events and motivate new design principles for tuning aggregation dynamics in tissue engineering applications.

  3. Different cell fates from cell-cell interactions: core architectures of two-cell bistable networks.

    Science.gov (United States)

    Rouault, Hervé; Hakim, Vincent

    2012-02-08

    The acquisition of different fates by cells that are initially in the same state is central to development. Here, we investigate the possible structures of bistable genetic networks that can allow two identical cells to acquire different fates through cell-cell interactions. Cell-autonomous bistable networks have been previously sampled using an evolutionary algorithm. We extend this evolutionary procedure to take into account interactions between cells. We obtain a variety of simple bistable networks that we classify into major subtypes. Some have long been proposed in the context of lateral inhibition through the Notch-Delta pathway, some have been more recently considered and others appear to be new and based on mechanisms not previously considered. The results highlight the role of posttranscriptional interactions and particularly of protein complexation and sequestration, which can replace cooperativity in transcriptional interactions. Some bistable networks are entirely based on posttranscriptional interactions and the simplest of these is found to lead, upon a single parameter change, to oscillations in the two cells with opposite phases. We provide qualitative explanations as well as mathematical analyses of the dynamical behaviors of various created networks. The results should help to identify and understand genetic structures implicated in cell-cell interactions and differentiation. Copyright © 2012 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  4. Cell-cell interactions mediate cytoskeleton organization and collective endothelial cell chemotaxis.

    Science.gov (United States)

    Shamloo, Amir

    2014-09-01

    This study investigates the role of cell-cell and cell-ligand interactions in cytoskeleton organization of endothelial cells (ECs) and their directional migration within a microfluidic device. The migration of ECs in response to a biochemical factor was studied. Mathematical analysis of the cell migration pathways and cellular cytoskeleton revealed that directional migration, migration persistence length, migration speed, and cytoskeletal stress fiber alignment can be mediated by the level of cell contacts as well as the presence or absence of a biochemical polarizing factor. It was shown that in the presence of a biochemical polarizing factor, higher cell density and more frequent cell contacts has a reinforcing effect on collective cell chemotaxis. In contrast, in the absence of a polarizing factor, high cell density can decrease or suppress the ability of the cells to migrate. Also, the correlation of actin stress fiber organization and alignment with directional migration of ECs was investigated. It was shown that in the presence of a biochemical polarizing factor, stress fibers within the cytoskeleton of ECs can be significantly aligned parallel to the gradient direction when the cells have higher level of contacts. The results also show that the organization and alignment of actin stress fibers is mediated by cell adhesion junctions during collective cell migration and introduce cell-cell interactions as a key factor during collective cell chemotaxis. © 2014 Wiley Periodicals, Inc.

  5. Communication & Management

    CERN Multimedia

    2006-01-01

    Calendar of courses for September to December 2006 Please check our Web site to find out the number of places available, which may vary. Management Curriculum 2nd semester 2006 Titles Dates Language Quality Management 18, 19 September Bilingual Managing Teams 19, 20, 21 September English Communicating Effectively - Residential 20, 21, 22 septembre Bilingual (Full) Personal Awareness & Impact 26, 27, 28 September Bilingual Introduction to Leadership 4, 5, 6 October Bilingue IProject Scheduling & Costing 12, 13 October English CDP-SL part 1 Several sessions Dates to be fixed English or French Personal Awareness & Impact 23, 24 October Bilingual Communicating to Convince 23, 24, 25 October Bilingual CDP-GL part 2 25, 26, 27 October English CDP-GL part 1 Dates to be fixed Bilingual Risk Management 20, 21 December Bilingual Communication curriculum 2nd semester 2006 Titles Dates Language Techniques d'exposé et de présentation 18, 19 s...

  6. Management & Communication

    CERN Multimedia

    2006-01-01

    Calendar of courses for September to December 2006 Please check our Web site to find out the number of places available, which may vary. Management Curriculum 2nd semester 2006 Titles Dates Language Quality Management 18, 19 September Bilingual Managing Teams 19, 20, 21 September English Communicating Effectively - Residential 20, 21, 22 septembre Bilingual (Full) Personal Awareness & Impact 26, 27, 28 September Bilingual Introduction to Leadership 4, 5, 6 October Bilingue IProject Scheduling & Costing 12, 13 October English CDP-SL part 1 Several sessions Dates to be fixed English or French Personal Awareness & Impact 23, 24 October Bilingual Communicating to Convince 23, 24, 25 October Bilingual CDP-GL part 2 25, 26, 27 October English CDP-GL part 1 Dates to be fixed Bilingual Risk Management 20, 21 December Bilingual Communication curriculum 2nd semester 2006 Titles Dates Language Techniques d'exposé et de présentation 18, 19 sept...

  7. Interlimb communication

    DEFF Research Database (Denmark)

    Stevenson, Andrew James Thomas

    A continual coordination between the two legs is necessary for maintaining a symmetric walking pattern and adapting to changes in the external environment. Recent evidence in animals and humans suggests that spinal interneuronal circuits under supraspinal control may mediate communication between...... the lower limbs. The overall objective of the present thesis was to further investigate and elucidate neural pathways underlying interlimb communication in humans, focusing primarily on the possible interlimb connections to the biceps femoris muscle. The major aims were 1) to investigate whether interlimb...... walking (Study IV). The results of the this thesis provide new insights into the neural mechanisms underlying human interlimb communication, as well as their functional relevance to human locomotion. Although it is difficult to propose the exact neural pathways mediating interlimb reflexes...

  8. Communications standards

    CERN Document Server

    Stokes, A V

    1986-01-01

    Communications Standards deals with the standardization of computer communication networks. This book examines the types of local area networks (LANs) that have been developed and looks at some of the relevant protocols in more detail. The work of Project 802 is briefly discussed, along with a protocol which has developed from one of the LAN standards and is now a de facto standard in one particular area, namely the Manufacturing Automation Protocol (MAP). Factors that affect the usage of networks, such as network management and security, are also considered. This book is divided into three se

  9. Constructive communication

    CERN Document Server

    Ellis, Richard

    2012-01-01

    Richard Ellis is a consultant in communications and the successful author of 'Communication for Engineers'. In each chapter he highlights key points and situations, and provides exercises to consolidate what has already been learnt. The book ends with a 'toolbox' of useful information on subjects such as writing letters, spelling, punctuation, using abbreviations, studying for exams, using libraries and training.Written in clear, informative English, with the emphasis on the practical, this book is essential reading for both students and professionals in the con

  10. Digital communication

    CERN Document Server

    Das, Apurba

    2010-01-01

    ""Digital Communications"" presents the theory and application of the philosophy of Digital Communication systems in a unique but lucid form. This book inserts equal importance to the theory and application aspect of the subject whereby the authors selected a wide class of problems. The Salient features of the book are: the foundation of Fourier series, Transform and wavelets are introduces in a unique way but in lucid language; the application area is rich and resemblance to the present trend of research, as we are attached with those areas professionally; a CD is included which contains code

  11. Induction of cell-cell fusion by ectromelia virus is not inhibited by its fusion inhibitory complex

    Directory of Open Access Journals (Sweden)

    Fuchs Pinhas

    2009-09-01

    Full Text Available Abstract Background Ectromelia virus, a member of the Orthopox genus, is the causative agent of the highly infectious mousepox disease. Previous studies have shown that different poxviruses induce cell-cell fusion which is manifested by the formation of multinucleated-giant cells (polykaryocytes. This phenomenon has been widely studied with vaccinia virus in conditions which require artificial acidification of the medium. Results We show that Ectromelia virus induces cell-cell fusion under neutral pH conditions and requires the presence of a sufficient amount of viral particles on the plasma membrane of infected cells. This could be achieved by infection with a replicating virus and its propagation in infected cells (fusion "from within" or by infection with a high amount of virus particles per cell (fusion "from without". Inhibition of virus maturation or inhibition of virus transport on microtubules towards the plasma membrane resulted in a complete inhibition of syncytia formation. We show that in contrast to vaccinia virus, Ectromelia virus induces cell-cell fusion irrespectively of its hemagglutination properties and cell-surface expression of the orthologs of the fusion inhibitory complex, A56 and K2. Additionally, cell-cell fusion was also detected in mice lungs following lethal respiratory infection. Conclusion Ectromelia virus induces spontaneous cell-cell fusion in-vitro and in-vivo although expressing an A56/K2 fusion inhibitory complex. This syncytia formation property cannot be attributed to the 37 amino acid deletion in ECTV A56.

  12. Health communication

    DEFF Research Database (Denmark)

    Sørensen, Mariann B.

    communication changes from information to conversation and negotiation of a chared understanding and challenges the concept of professionalism. The success of conversations depends on the interactions and the capacity to deal with several voices in a complex context. The study discusses the opportunity...

  13. COMMUNICATIONS GROUP

    CERN Multimedia

    L. Taylor

    2010-01-01

    The recently established CMS Communications Group, led by Lucas Taylor, has been busy in all three of its main are areas of responsibility: Communications Infrastructure, Information Systems, and Outreach and Education Communications Infrastructure The damage caused by the flooding of the CMS Centre@CERN on 21st December has been completely repaired and all systems are back in operation. Major repairs were made to the roofs, ceilings and one third of the floor had to be completely replaced. Throughout these works, the CMS Centre was kept operating and even hosted a major press event for first 7 TeV collisions, as described below. Incremental work behind the scenes is steadily improving the quality of the CMS communications infrastructure, particularly Webcasting, video conferencing, and meeting rooms at CERN. CERN/IT is also deploying a pilot service of a new videoconference tool called Vidyo, to assess whether it might provide an enhanced service at a lower cost, compared to the EVO tool currently in w...

  14. COMMUNICATIONS GROUP

    CERN Multimedia

    L. Taylor

    2010-01-01

    The CMS Communications Group, established at the start of 2010, has been strengthening the activities in all three areas of its responsibility: (1) Communications Infrastructure, (2) Information Systems, and (3) Outreach and Education. Communications Infrastructure The Communications Group has invested a lot of effort to support the operations needs of CMS. Hence, the CMS Centres where physicists work on remote CMS shifts, Data Quality Monitoring, and Data Analysis are running very smoothly. There are now 55 CMS Centres worldwide, up from just 16 at the start of CMS data-taking. The latest to join are Imperial College London, the University of Iowa, and the Università di Napoli. The CMS Centre@CERN in Meyrin, which is now full repaired after the major flooding at the beginning of the year, has been at the centre of CMS offline and computing operations, most recently hosting a large fraction of the CMS Heavy Ion community during the lead-lead run. A number of sub-detector shifts can now take pla...

  15. Communication & Aging.

    Science.gov (United States)

    Arnold, William E.

    This extensive bibliography contains more than 1,800 entries about communication and aging. The citations include journal articles, unpublished papers, speeches, dissertations, research studies, and books that relate aging and the aged to a variety of topics, including the following: physiological deterioration, socialization, political…

  16. Short communication

    African Journals Online (AJOL)

    UPuser

    Short communication. Polymorphisms of the CAST gene in the Meishan and five other pig populations in China. Q.S. Wang. 1. , Y.C. Pan. 1#. , L.B. Sun. 2 and H. Meng. 1. 1 Department of Animal Science, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai. 201101, P.R. China. 2 Shanghai Institute of ...

  17. Communication Complexity

    Indian Academy of Sciences (India)

    Jaikumar Radhakrishnan

    We allow a small probability of error. Goal: minimize the total number of bits transmitted. ... using tools from combinatorics, coding theory, algebra, analysis, etc. Jaikumar Radhakrishnan. Communication .... Assume Alice and Bob know a good error correcting code. E : {0, 1}n → {0, 1}10n with distance, say, 3n. Alice.

  18. Communication Planning.

    Science.gov (United States)

    Development Communication Report, 1978

    1978-01-01

    Communication planning in developing countries is discussed in individual articles on theory, knowledge production and utilization, planning at the regional level, software, and rural development. A nutrition education project and three experiments in developing educational materials with feedback from villagers in Africa are described in the…

  19. SHORT COMMUNICATION

    African Journals Online (AJOL)

    a

    ______. *Corresponding author. E-mail: vani_chem@yahoo.com. SHORT COMMUNICATION. OXIDATION OF L-CYSTINE BY CHROMIUM(VI) - A KINETIC STUDY. Kalyan Kumar Adari, Annapurna Nowduri and Vani Parvataneni*. Department of Inorganic and Analytical Chemistry, School of Chemistry, Andhra University,.

  20. Communication Theory.

    Science.gov (United States)

    Penland, Patrick R.

    Three papers are presented which delineate the foundation of theory and principles which underlie the research and instructional approach to communications at the Graduate School of Library and Information Science, University of Pittsburgh. Cybernetic principles provide the integration, and validation is based in part on a situation-producing…

  1. Quantum communications

    CERN Document Server

    Cariolaro, Gianfranco

    2015-01-01

    This book demonstrates that a quantum communication system using the coherent light of a laser can achieve performance orders of magnitude superior to classical optical communications Quantum Communications provides the Masters and PhD signals or communications student with a complete basics-to-applications course in using the principles of quantum mechanics to provide cutting-edge telecommunications. Assuming only knowledge of elementary probability, complex analysis and optics, the book guides its reader through the fundamentals of vector and Hilbert spaces and the necessary quantum-mechanical ideas, simply formulated in four postulates. A turn to practical matters begins with and is then developed by: ·         development of the concept of quantum decision, emphasizing the optimization of measurements to extract useful information from a quantum system; ·         general formulation of a transmitter–receiver system ·         particular treatment of the most popular quantum co...

  2. COMMUNICATIONS GROUP

    CERN Multimedia

    L. Taylor

    2011-01-01

    The CMS Communications Group has been busy in all three areas of its responsibility: (1) Communications Infrastructure, (2) Information Systems, and (3) Outreach and Education. Communications Infrastructure The 55 CMS Centres worldwide are well used by physicists working on remote CMS shifts, Computing operations, data quality monitoring, data analysis and outreach. The CMS Centre@CERN in Meyrin, is the centre of the CMS Offline and Computing operations, and a number of subdetector shifts can now take place there, rather than in the main Control Room at P5. A new CMS meeting room has been equipped for videoconferencing in building 42, next to building 40. Our building 28 meeting room and the facilities at P5 will be refurbished soon and plans are underway to steadily upgrade the ageing equipment in all 15 CMS meeting rooms at CERN. The CMS evaluation of the Vidyo tool indicates that it is not yet ready to be considered as a potential replacement for EVO. The Communications Group provides the CMS-TV (web) cha...

  3. Crisis Communication

    OpenAIRE

    Anca Jarmila Guţă

    2006-01-01

    The paper presents the manner in which the crisis of different types can disturb the normal activity of an organization and also the modalities by which the communication in this situation can solve or attenuate the negative effects of a crisis.

  4. Core Communications

    Science.gov (United States)

    Block, Greg; Ross, J. D.; Mulder, David

    2011-01-01

    The website--it is where people go to find out anything and everything about a school, college, or university. In the relatively short life of the Internet, institutional websites have moved from the periphery to center stage and become strategically integral communications and marketing tools. As the flow of information accelerates and new…

  5. Astronomy Communication

    Science.gov (United States)

    Heck, A.; Madsen, C.

    2003-07-01

    Astronomers communicate all the time, with colleagues of course, but also with managers and administrators, with decision makers and takers, with social representatives, with the news media, and with the society at large. Education is naturally part of the process. Astronomy communication must take into account several specificities: the astronomy community is rather compact and well organized world-wide; astronomy has penetrated the general public remarkably well with an extensive network of associations and organizations of aficionados all over the world. Also, as a result of the huge amount of data accumulated and by necessity for their extensive international collaborations, astronomers have pioneered the development of distributed resources, electronic communications and networks coupled to advanced methodologies and technologies, often much before they become of common world-wide usage. This book is filling up a gap in the astronomy-related literature by providing a set of chapters not only of direct interest to astronomy communication, but also well beyond it. The experts contributing to this book have done their best to write in a way understandable to readers not necessarily hyperspecialized in astronomy nor in communication techniques while providing specific detailed information, as well as plenty of pointers and bibliographic elements. This book will be very useful for researchers, teachers, editors, publishers, librarians, computer scientists, sociologists of science, research planners and strategists, project managers, public-relations officers, plus those in charge of astronomy-related organizations, as well as for students aiming at a career in astronomy or related space science. Link: http://www.wkap.nl/prod/b/1-4020-1345-0

  6. Communicating Science

    Science.gov (United States)

    Russell, Nicholas

    2009-10-01

    Introduction: what this book is about and why you might want to read it; Prologue: three orphans share a common paternity: professional science communication, popular journalism, and literary fiction are not as separate as they seem; Part I. Professional Science Communication: 1. Spreading the word: the endless struggle to publish professional science; 2. Walk like an Egyptian: the alien feeling of professional science writing; 3. The future's bright? Professional science communication in the age of the internet; 4. Counting the horse's teeth: professional standards in science's barter economy; 5. Separating the wheat from the chaff: peer review on trial; Part II. Science for the Public: What Science Do People Need and How Might They Get It?: 6. The Public Understanding of Science (PUS) movement and its problems; 7. Public engagement with science and technology (PEST): fine principle, difficult practice; 8. Citizen scientists? Democratic input into science policy; 9. Teaching and learning science in schools: implications for popular science communication; Part III. Popular Science Communication: The Press and Broadcasting: 10. What every scientist should know about mass media; 11. What every scientist should know about journalists; 12. The influence of new media; 13. How the media represents science; 14. How should science journalists behave?; Part IV. The Origins of Science in Cultural Context: Five Historic Dramas: 15. A terrible storm in Wittenberg: natural knowledge through sorcery and evil; 16. A terrible storm in the Mediterranean: controlling nature with white magic and religion; 17. Thieving magpies: the subtle art of false projecting; 18. Foolish virtuosi: natural philosophy emerges as a distinct discipline but many cannot take it seriously; 19. Is scientific knowledge 'true' or should it just be 'truthfully' deployed?; Part V. Science in Literature: 20. Science and the Gothic: the three big nineteenth-century monster stories; 21. Science fiction: serious

  7. Digital communication communication, multimedia, security

    CERN Document Server

    Meinel, Christoph

    2014-01-01

    The authors give a detailed summary about the fundamentals and the historical background of digital communication. This includes an overview of the encoding principles and algorithms of textual information, audio information, as well as images, graphics, and video in the Internet. Furthermore the fundamentals of computer networking, digital security and cryptography are covered. Thus, the book provides a well-founded access to communication technology of computer networks, the internet and the WWW. Numerous pictures and images, a subject-index and a detailed list of historical personalities in

  8. Cell Adhesions: Actin-Based Modules that Mediate Cell-Extracellular Matrix and Cell-Cell Interactions

    Science.gov (United States)

    Bachir, Alexia; Horwitz, Alan Rick; Nelson, W. James; Bianchini, Julie M.

    2018-01-01

    Cell adhesions link cells to the extracellular matrix (ECM) and to each other, and depend on interactions with the actin cytoskeleton. Both cell-ECM and cell-cell adhesion sites contain discrete, yet overlapping functional modules. These modules establish physical association with the actin cytoskeleton, locally modulate actin organization and dynamics, and trigger intracellular signaling pathways. Interplay between these modules generates distinct actin architectures that underlie different stages, types, and functions of cell-ECM and cell-cell adhesions. Actomyosin contractility is required to generate mature, stable adhesions, as well as sense and translate the mechanical properties of the cellular environment to changes in cell organization and behavior. In this chapter we discuss the organization and function of different adhesion modules and how they interact with the actin cytoskeleton. We highlight the molecular mechanisms of mechanotransduction in adhesions, and how adhesion molecules mediate crosstalk between cell-ECM and cell-cell adhesion sites. PMID:28679638

  9. Influence of Cell-Cell Interactions on the Population Growth Rate in a Tumor

    Science.gov (United States)

    Chen, Yong

    2017-12-01

    The understanding of the macroscopic phenomenological models of the population growth at a microscopic level is important to predict the population behaviors emerged from the interactions between the individuals. In this work, we consider the influence of the population growth rate R on the cell-cell interaction in a tumor system and show that, in most cases especially small proliferative probabilities, the regulative role of the interaction will be strengthened with the decline of the intrinsic proliferative probabilities. For the high replication rates of an individual and the cooperative interactions, the proliferative probability almost has no effect. We compute the dependences of R on the interactions between the cells under the approximation of the nearest neighbor in the rim of an avascular tumor. Our results are helpful to qualitatively understand the influence of the interactions between the individuals on the growth rate in population systems. Supported by the National Natural Science Foundation of China under Grant Nos. 11675008 and 21434001

  10. Free-zone electrophoresis of animal cells. 1: Experiments on cell-cell interactions

    Science.gov (United States)

    Todd, P. W.; Hjerten, S.

    1985-01-01

    The electrophoretically migrating zones wasa monitored. The absence of fluid flows in the direction of migration permits direct measurement of electrophoretic velocities of any material. Sedimentation is orthogonal to electrokinetic motion and the effects of particle-particle interaction on electrophoretic mobility is studied by free zone electrophoresis. Fixed erythrocytes at high concentrations, mixtures of fixed erythrocytes from different animal species, and mixtures of cultured human cells were studied in low ionic strength buffers. The electrophoretic velocity of fixed erythrocytes was not altered by increasing cell concentration or by the mixing of erythrocytes from different species. When zones containing cultured human glial cells and neuroblastoma cells are permitted to interact during electrophoresis, altered migration patterns occur. It is found that cell-cell interactions depends upon cell type.

  11. Short Communication

    African Journals Online (AJOL)

    huis

    Short Communication. QTL analysis of production traits on SSC3 in a Large White×Meishan pig resource family. B. Zuo. 1. , Y.Z. Xiong. 1#. , Y.H. Su. 2. , C.Y. Deng. 1. , M.G. Lei. 1. , F.E. Li. 1. , R. Zheng. 1 and S.W. Jiang. 1. 1 Key Laboratory of Swine Genetics and Breeding, Ministry of Agriculture & Key Lab of Agricultural ...

  12. Communication Strategies

    OpenAIRE

    Strate, Simon Wolter; Loznica, Javor; Nærland, Kristoffer; Skipper, Mads Christian; Jensen, Charlotte Haagen

    2013-01-01

    This project focuses on the oil company, Shell, and their way of conducting themselves on social media sites, specifically Facebook and twitter. We establish this by using social media theory, and corporate campaign theories, and applying these to the content that Shell puts out on these particular social media sites. Furthermore, the project establishes a critical evaluation of the weight and presence of social media within modern corporate communication and issue management. This project...

  13. Involvement of JAK2 upstream of the PI 3-kinase in cell-cell adhesion regulation by gastrin

    International Nuclear Information System (INIS)

    Ferrand, Audrey; Kowalski-Chauvel, Aline; Bertrand, Claudine; Pradayrol, Lucien; Fourmy, Daniel; Dufresne, Marlene; Seva, Catherine

    2004-01-01

    The Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway has been implicated in cell transformation and proliferation. Besides aberrant cell proliferation, loss of cell-cell adhesion during epithelial-mesenchymal transition (EMT) is an important event which occurs during development of epithelial cancers. However, the role of JAK-dependent pathways in this process is not known. We analyzed the involvement of these pathways in the regulation of E-cadherin-dependent cell-cell adhesion by gastrin, a mitogenic factor for gastrointestinal (GI) tract. We identified JAK2/STAT3 as a new pathway in gastrin signaling. We demonstrated that JAK2 functions as an upstream mediator of the phosphatidylinositol 3 (PI 3)-kinase activity in gastrin signaling. Indeed, we observed a coprecipitation of both kinases and an inhibition of gastrin-induced PI 3-kinase activation when JAK2 activity is blocked. We also demonstrated that loss of cell-cell adhesion and the increase in cell motility induced by gastrin required the activation of JAK2 and the PI 3-kinase. Indeed, the modifications in localization of adherens junctions proteins and the migration, observed in gastrin-stimulated cells, were reversed by inhibition of both kinases. These results described the involvement of JAK2 in the modulation of cell-cell adhesion in epithelial cells. They support a possible role of JAK2 in the epithelial-mesenchymal transition which occurs during malignant development

  14. Rac1 acts in conjunction with Nedd4 and dishevelled-1 to promote maturation of cell-cell contacts

    NARCIS (Netherlands)

    M. Nethe (Micha); B.J. de Kreuk (Bart-Jan); D.V.F. Tauriello (Daniele); E.C. Anthony (Eloise); B. Snoek (Barbara); T. Stumpel (Thomas); M. Salinas; K. Maurice (Karelle); D. Geerts (Dirk); A.M. Deelder (André); P. Hensbergen (Paul); P.L. Hordijk (Peter )

    2012-01-01

    textabstractThe Rho-GTPase Rac1 promotes actin polymerization and membrane protrusion that mediate initial contact and subsequent maturation of cell-cell junctions. Here we report that Rac1 associates with the ubiquitin-protein ligase neural precursor cell expressed developmentally down-regulated 4

  15. Quantitative imaging of epithelial cell scattering identifies specific inhibitors of cell motility and cell-cell dissociation

    NARCIS (Netherlands)

    Loerke, D.; le Duc, Q.; Blonk, I.; Kerstens, A.; Spanjaard, E.; Machacek, M.; Danuser, G.; de Rooij, J.

    2012-01-01

    The scattering of cultured epithelial cells in response to hepatocyte growth factor (HGF) is a model system that recapitulates key features of metastatic cell behavior in vitro, including disruption of cell-cell adhesions and induction of cell migration. We have developed image analysis tools that

  16. Communication theory

    CERN Document Server

    Goldie, Charles M

    1991-01-01

    This book is an introduction, for mathematics students, to the theories of information and codes. They are usually treated separately but, as both address the problem of communication through noisy channels (albeit from different directions), the authors have been able to exploit the connection to give a reasonably self-contained treatment, relating the probabilistic and algebraic viewpoints. The style is discursive and, as befits the subject, plenty of examples and exercises are provided. Some examples and exercises are provided. Some examples of computer codes are given to provide concrete illustrations of abstract ideas.

  17. Risk communication

    International Nuclear Information System (INIS)

    Dombrowsky, Wolf R.; Kiel Univ.

    2009-01-01

    The study on risk communication identifies the deficiencies concerning empirical and theoretical knowledge on objective radiation hazards of the acting personnel (managers, politicians, jurists, etc.) in administrations, governmental agencies, and business management. This is especially problematic with respect to emergency planning and estimations concerning the public behavior. The incident/accident information in Germany is discussed based on the legislative regulations revealing the controversial perception between industry, legislative and public interest. Further topics include the meandering of the modern safety semantics and the public opinion concerning catastrophic risk.

  18. Interdisciplinary Communication

    Directory of Open Access Journals (Sweden)

    Nagib Callaos

    2013-12-01

    Full Text Available Communication is fundamental in scientific practice and an integral part of academic work. The practice of communication cannot be neglected by those who are trying to advance scientific research. Effective means should continuously be identified in order to open channels of communication within and among disciplines, among scientists and between scientists and the general public.[1]The increasing importance of interdisciplinary communication has been pointed out by an increasing number of researchers and scholars, as well as in conferences and roundtables on the subject. Some authors even estimate that "interdisciplinary study represents the future of the university."[2] Since interdisciplinary study is "the most underthought critical, pedagogical and institutional concept in modern academy"[3] it is important to think and reflect, and even do some research, on this concept or notion. Research and practice based reflections with regards to this issue are important especially because the increasing complexity and proliferation of scientific research is generating countless specialties, sub-specialties and sub-sub-specialties, with their respective special languages; which were "created for discrete local areas of research based upon the disconnected branches of science."[4] On the other hand, scientific, technical and societal problems are requiring multi- or inter-disciplinary consideration. Consequently, interdisciplinary communication channels are being needed with urgency, and scientific research should be integrated, not just in the context of its discipline, but also in the context of related disciplines. Much more reflection and research should be done on this issue. Research on adequate research integration and communication is urgently required, i.e. meta-research efforts should be done in order to relate research results in an adequate and more useful way. This meta-research effort might be done in the context of each particular

  19. Intercultural Communication Ethics and Communication Competence%Intercultural Communication Ethics and Communication Competence

    Institute of Scientific and Technical Information of China (English)

    时婷洁

    2012-01-01

    This paper investigates intercultural communication ethics is a vital element to promote intercultural communication competence. Firstly, it defines the concept of intercultural communication ethics; Secondly, it illustrates the relation between ethics and the key point of intercultural communication competence; and finally addresses how intercultural communication ethics can improve intercultural communication competence.

  20. Cell-cell junctions: a target of acoustic overstimulation in the sensory epithelium of the cochlea

    Directory of Open Access Journals (Sweden)

    Zheng Guiliang

    2012-06-01

    Full Text Available Abstract Background Exposure to intense noise causes the excessive movement of the organ of Corti, stretching the organ and compromising sensory cell functions. We recently revealed changes in the transcriptional expression of multiple adhesion-related genes during the acute phases of cochlear damage, suggesting that the disruption of cell-cell junctions is an early event in the process of cochlear pathogenesis. However, the functional state of cell junctions in the sensory epithelium is not clear. Here, we employed graded dextran-FITC, a macromolecule tracer that is impermeable to the organ of Corti under physiological conditions, to evaluate the barrier function of cell junctions in normal and noise-traumatized cochlear sensory epithelia. Results Exposure to an impulse noise of 155 dB (peak sound pressure level caused a site-specific disruption in the intercellular junctions within the sensory epithelium of the chinchilla cochlea. The most vulnerable sites were the junctions among the Hensen cells and between the Hensen and Deiters cells within the outer zone of the sensory epithelium. The junction clefts that formed in the reticular lamina were permeable to 40 and 500 but not 2,000 kDa dextran-FITC macromolecules. Moreover, this study showed that the interruption of junction integrity occurred in the reticular lamina and also in the basilar membrane, a site that had been considered to be resistant to acoustic injury. Finally, our study revealed a general spatial correlation between the site of sensory cell damage and the site of junction disruption. However, the two events lacked a strict one-to-one correlation, suggesting that the disruption of cell-cell junctions is a contributing, but not the sole, factor for initiating acute sensory cell death. Conclusions Impulse noise causes the functional disruption of intercellular junctions in the sensory epithelium of the chinchilla cochlea. This disruption occurs at an early phase of cochlear

  1. Data communications and computer communications network

    International Nuclear Information System (INIS)

    Kim, Jang Gwon; Gu, Chang Hoe

    2005-03-01

    This textbook is composed of twelve chapters, which are communication network introduction, foundation of data communication, data link control, circuit switching system, packet switching system, multiple access communication system, protocol and architecture, LAN, MAN communication network, integrated service digital network, internet and Asymmetric digital subscriber Line and Wireless Local Loop. Each chapter has the introduction of the technique, structure, function and practice problems. It also has the appendix on electricity and communication standards organization, characteristic table and glossary.

  2. Molecular mechanisms of cell-cell spread of intracellular bacterial pathogens.

    Science.gov (United States)

    Ireton, Keith

    2013-07-17

    Several bacterial pathogens, including Listeria monocytogenes, Shigella flexneri and Rickettsia spp., have evolved mechanisms to actively spread within human tissues. Spreading is initiated by the pathogen-induced recruitment of host filamentous (F)-actin. F-actin forms a tail behind the microbe, propelling it through the cytoplasm. The motile pathogen then encounters the host plasma membrane, forming a bacterium-containing protrusion that is engulfed by an adjacent cell. Over the past two decades, much progress has been made in elucidating mechanisms of F-actin tail formation. Listeria and Shigella produce tails of branched actin filaments by subverting the host Arp2/3 complex. By contrast, Rickettsia forms tails with linear actin filaments through a bacterial mimic of eukaryotic formins. Compared with F-actin tail formation, mechanisms controlling bacterial protrusions are less well understood. However, recent findings have highlighted the importance of pathogen manipulation of host cell-cell junctions in spread. Listeria produces a soluble protein that enhances bacterial protrusions by perturbing tight junctions. Shigella protrusions are engulfed through a clathrin-mediated pathway at 'tricellular junctions'--specialized membrane regions at the intersection of three epithelial cells. This review summarizes key past findings in pathogen spread, and focuses on recent developments in actin-based motility and the formation and internalization of bacterial protrusions.

  3. Synergy of cell-cell repulsion and vacuolation in a computational model of lumen formation.

    Science.gov (United States)

    Boas, Sonja E M; Merks, Roeland M H

    2014-03-06

    A key step in blood vessel development (angiogenesis) is lumen formation: the hollowing of vessels for blood perfusion. Two alternative lumen formation mechanisms are suggested to function in different types of blood vessels. The vacuolation mechanism is suggested for lumen formation in small vessels by coalescence of intracellular vacuoles, a view that was extended to extracellular lumen formation by exocytosis of vacuoles. The cell-cell repulsion mechanism is suggested to initiate extracellular lumen formation in large vessels by active repulsion of adjacent cells, and active cell shape changes extend the lumen. We used an agent-based computer model, based on the cellular Potts model, to compare and study both mechanisms separately and combined. An extensive sensitivity analysis shows that each of the mechanisms on its own can produce lumens in a narrow region of parameter space. However, combining both mechanisms makes lumen formation much more robust to the values of the parameters, suggesting that the mechanisms may work synergistically and operate in parallel, rather than in different vessel types.

  4. Regulation of promyogenic signal transduction by cell-cell contact and adhesion

    International Nuclear Information System (INIS)

    Krauss, Robert S.

    2010-01-01

    Skeletal myoblast differentiation involves acquisition of the muscle-specific transcriptional program and morphological changes, including fusion into multinucleated myofibers. Differentiation is regulated by extracellular signaling cues, including cell-cell contact and adhesion. Cadherin and Ig adhesion receptors have been implicated in distinct but overlapping stages of myogenesis. N-cadherin signals through the Ig receptor Cdo to activate p38 MAP kinase, while the Ig receptor neogenin signals to activate FAK; both processes promote muscle-specific gene expression and myoblast fusion. M-cadherin activates Rac1 to enhance fusion. Specific Ig receptors (Kirre and Sns) are essential for myoblast fusion in Drosophila, also signaling through Rac, and vertebrate orthologs of Kirre and Sns have partially conserved function. Mice lacking specific cytoplasmic signaling factors activated by multiple receptors (e.g., Rac1) have strong muscle phenotypes in vivo. In contrast, mice lacking individual adhesion receptors that lie upstream of these factors have modest phenotypes. Redundancy among receptors may account for this. Many of the mammalian Ig receptors and cadherins associate with each other, and multivalent interactions within these complexes may require removal of multiple components to reveal dramatic defects in vivo. Nevertheless, it is possible that the murine adhesion receptors rate-limiting in vivo have not yet been identified or fully assessed.

  5. Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells.

    Science.gov (United States)

    Jossin, Yves; Lee, Minhui; Klezovitch, Olga; Kon, Elif; Cossard, Alexia; Lien, Wen-Hui; Fernandez, Tania E; Cooper, Jonathan A; Vasioukhin, Valera

    2017-06-05

    Malformations of the cerebral cortex (MCCs) are devastating developmental disorders. We report here that mice with embryonic neural stem-cell-specific deletion of Llgl1 (Nestin-Cre/Llgl1 fl/fl ), a mammalian ortholog of the Drosophila cell polarity gene lgl, exhibit MCCs resembling severe periventricular heterotopia (PH). Immunohistochemical analyses and live cortical imaging of PH formation revealed that disruption of apical junctional complexes (AJCs) was responsible for PH in Nestin-Cre/Llgl1 fl/fl brains. While it is well known that cell polarity proteins govern the formation of AJCs, the exact mechanisms remain unclear. We show that LLGL1 directly binds to and promotes internalization of N-cadherin, and N-cadherin/LLGL1 interaction is inhibited by atypical protein kinase C-mediated phosphorylation of LLGL1, restricting the accumulation of AJCs to the basolateral-apical boundary. Disruption of the N-cadherin-LLGL1 interaction during cortical development in vivo is sufficient for PH. These findings reveal a mechanism responsible for the physical and functional connection between cell polarity and cell-cell adhesion machineries in mammalian cells. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Regulation of promyogenic signal transduction by cell-cell contact and adhesion

    Energy Technology Data Exchange (ETDEWEB)

    Krauss, Robert S., E-mail: Robert.Krauss@mssm.edu [Department of Developmental and Regenerative Biology, Mount Sinai School of Medicine, New York, NY 10029 (United States)

    2010-11-01

    Skeletal myoblast differentiation involves acquisition of the muscle-specific transcriptional program and morphological changes, including fusion into multinucleated myofibers. Differentiation is regulated by extracellular signaling cues, including cell-cell contact and adhesion. Cadherin and Ig adhesion receptors have been implicated in distinct but overlapping stages of myogenesis. N-cadherin signals through the Ig receptor Cdo to activate p38 MAP kinase, while the Ig receptor neogenin signals to activate FAK; both processes promote muscle-specific gene expression and myoblast fusion. M-cadherin activates Rac1 to enhance fusion. Specific Ig receptors (Kirre and Sns) are essential for myoblast fusion in Drosophila, also signaling through Rac, and vertebrate orthologs of Kirre and Sns have partially conserved function. Mice lacking specific cytoplasmic signaling factors activated by multiple receptors (e.g., Rac1) have strong muscle phenotypes in vivo. In contrast, mice lacking individual adhesion receptors that lie upstream of these factors have modest phenotypes. Redundancy among receptors may account for this. Many of the mammalian Ig receptors and cadherins associate with each other, and multivalent interactions within these complexes may require removal of multiple components to reveal dramatic defects in vivo. Nevertheless, it is possible that the murine adhesion receptors rate-limiting in vivo have not yet been identified or fully assessed.

  7. Follow-the-leader cell migration requires biased cell-cell contact and local microenvironmental signals

    Science.gov (United States)

    Wynn, Michelle L.; Rupp, Paul; Trainor, Paul A.; Schnell, Santiago; Kulesa, Paul M.

    2013-06-01

    Directed cell migration often involves at least two types of cell motility that include multicellular streaming and chain migration. However, what is unclear is how cell contact dynamics and the distinct microenvironments through which cells travel influence the selection of one migratory mode or the other. The embryonic and highly invasive neural crest (NC) are an excellent model system to study this question since NC cells have been observed in vivo to display both of these types of cell motility. Here, we present data from tissue transplantation experiments in chick and in silico modeling that test our hypothesis that cell contact dynamics with each other and the microenvironment promote and sustain either multicellular stream or chain migration. We show that when premigratory cranial NC cells (at the pre-otic level) are transplanted into a more caudal region in the head (at the post-otic level), cells alter their characteristic stream behavior and migrate in chains. Similarly, post-otic NC cells migrate in streams after transplantation into the pre-otic hindbrain, suggesting that local microenvironmental signals dictate the mode of NC cell migration. Simulations of an agent-based model (ABM) that integrates the NC cell behavioral data predict that chain migration critically depends on the interplay of biased cell-cell contact and local microenvironment signals. Together, this integrated modeling and experimental approach suggests new experiments and offers a powerful tool to examine mechanisms that underlie complex cell migration patterns.

  8. The role of apical cell-cell junctions and associated cytoskeleton in mechanotransduction.

    Science.gov (United States)

    Sluysmans, Sophie; Vasileva, Ekaterina; Spadaro, Domenica; Shah, Jimit; Rouaud, Florian; Citi, Sandra

    2017-04-01

    Tissues of multicellular organisms are characterised by several types of specialised cell-cell junctions. In vertebrate epithelia and endothelia, tight and adherens junctions (AJ) play critical roles in barrier and adhesion functions, and are connected to the actin and microtubule cytoskeletons. The interaction between junctions and the cytoskeleton is crucial for tissue development and physiology, and is involved in the molecular mechanisms governing cell shape, motility, growth and signalling. The machineries which functionally connect tight and AJ to the cytoskeleton comprise proteins which either bind directly to cytoskeletal filaments, or function as adaptors for regulators of the assembly and function of the cytoskeleton. In the last two decades, specific cytoskeleton-associated junctional molecules have been implicated in mechanotransduction, revealing the existence of multimolecular complexes that can sense mechanical cues and translate them into adaptation to tensile forces and biochemical signals. Here, we summarise the current knowledge about the machineries that link tight and AJ to actin filaments and microtubules, and the molecular basis for mechanotransduction at epithelial and endothelial AJ. © 2017 Société Française des Microscopies and Société de Biologie Cellulaire de France. Published by John Wiley & Sons Ltd.

  9. Human papillomavirus 16 E5 induces bi-nucleated cell formation by cell-cell fusion

    International Nuclear Information System (INIS)

    Hu Lulin; Plafker, Kendra; Vorozhko, Valeriya; Zuna, Rosemary E.; Hanigan, Marie H.; Gorbsky, Gary J.; Plafker, Scott M.; Angeletti, Peter C.; Ceresa, Brian P.

    2009-01-01

    Human papillomaviruses (HPV) 16 is a DNA virus encoding three oncogenes - E5, E6, and E7. The E6 and E7 proteins have well-established roles as inhibitors of tumor suppression, but the contribution of E5 to malignant transformation is controversial. Using spontaneously immortalized human keratinocytes (HaCaT cells), we demonstrate that expression of HPV16 E5 is necessary and sufficient for the formation of bi-nucleated cells, a common characteristic of precancerous cervical lesions. Expression of E5 from non-carcinogenic HPV6b does not produce bi-nucleate cells. Video microscopy and biochemical analyses reveal that bi-nucleates arise through cell-cell fusion. Although most E5-induced bi-nucleates fail to propagate, co-expression of HPV16 E6/E7 enhances the proliferation of these cells. Expression of HPV16 E6/E7 also increases bi-nucleated cell colony formation. These findings identify a new role for HPV16 E5 and support a model in which complementary roles of the HPV16 oncogenes lead to the induction of carcinogenesis

  10. Crisis Communication

    International Nuclear Information System (INIS)

    Dunkle, M.K.

    1989-01-01

    The author discusses how one of the strongest examples of how destructive poor crisis communications can be the Three Mile Island accident of March 1979. This was an event that was minimal in its physical effects on the public and environment beyond the walls of that nuclear power plant. However, the emotional trauma on the local public, the economic impact on area businesses and property owners, and the long term impact on the entire nuclear utility industry were great. Approximately 80,000 people as far as 15 miles from the plant evacuated over a weekend. There have been no new orders for nuclear plants and many cancellations since the event 10 years ago. This paper presents an analysis of the accident at Three Mile Island

  11. Communication spaces.

    Science.gov (United States)

    Coiera, Enrico

    2014-01-01

    Annotations to physical workspaces such as signs and notes are ubiquitous. When densely annotated, work areas become communication spaces. This study aims to characterize the types and purpose of such annotations. A qualitative observational study was undertaken in two wards and the radiology department of a 440-bed metropolitan teaching hospital. Images were purposefully sampled; 39 were analyzed after excluding inferior images. Annotation functions included signaling identity, location, capability, status, availability, and operation. They encoded data, rules or procedural descriptions. Most aggregated into groups that either created a workflow by referencing each other, supported a common workflow without reference to each other, or were heterogeneous, referring to many workflows. Higher-level assemblies of such groupings were also observed. Annotations make visible the gap between work done and the capability of a space to support work. Annotations are repairs of an environment, improving fitness for purpose, fixing inadequacy in design, or meeting emergent needs. Annotations thus record the missing information needed to undertake tasks, typically added post-implemented. Measuring annotation levels post-implementation could help assess the fit of technology to task. Physical and digital spaces could meet broader user needs by formally supporting user customization, 'programming through annotation'. Augmented reality systems could also directly support annotation, addressing existing information gaps, and enhancing work with context sensitive annotation. Communication spaces offer a model of how work unfolds. Annotations make visible local adaptation that makes technology fit for purpose post-implementation and suggest an important role for annotatable information systems and digital augmentation of the physical environment.

  12. Airborne wireless communication systems, airborne communication methods, and communication methods

    Science.gov (United States)

    Deaton, Juan D [Menan, ID; Schmitt, Michael J [Idaho Falls, ID; Jones, Warren F [Idaho Falls, ID

    2011-12-13

    An airborne wireless communication system includes circuitry configured to access information describing a configuration of a terrestrial wireless communication base station that has become disabled. The terrestrial base station is configured to implement wireless communication between wireless devices located within a geographical area and a network when the terrestrial base station is not disabled. The circuitry is further configured, based on the information, to configure the airborne station to have the configuration of the terrestrial base station. An airborne communication method includes answering a 911 call from a terrestrial cellular wireless phone using an airborne wireless communication system.

  13. Communicative Musicality

    DEFF Research Database (Denmark)

    Holck, Ulla

    2010-01-01

    university, Stephen Malloch listened to tapes of mothers and their babies ‘chatting’ with each other, recorded by Trevarthen in the 70’s. One of the first tapes was the vocal interaction of Laura and her mother. “As I listened, intrigued by the fluid give and take of the communication, and the lilting speech...... of the mother as she chatted with her baby, I began to tap my foot. I am, by training, a musician, so I was very used to automatically feeling the beat as I listened to musical sounds.… I replaced the tape, and again, I could sense a distinct rhythmicity and melodious give and take to the gentle prompting...... therapy as purely protomusic. But with Malloch & Trevarthen’s focus on musicality as the innate human abilities that make music production and appreciation possible, this discussion can easily move on. These and many other essential discussions await us – thanks to this comprehensive – and demanding...

  14. Communicating EAM

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

     (Schaeffer’s work in Paris, the studio in Cologne and in the studio EMS in Stockholm) and in relation to today’s discussions of EAM and Sound Art. The extended rhetoric about the music and the production of it is a useful tool in our discussions of musical development and analysis, but can in some cases lead......Since the early years of electro acoustic music great self-awareness is found among the field’s composers who often and willingly have communicated historical chronology, thoughts about analysis, aesthetic directions and rivalries. This we find both in relation to the historical studios...... to the disappearing of the aesthetic work and contemplation. In the paper I will illustrate this by presenting an analysis of the rhetoric at the electronic music studio EMS, Stockholm: It’s aesthetic and scientific context and its function in a political context. I will discuss what impact this displacement of focus...

  15. COMMUNICATIONS GROUP

    CERN Multimedia

    L. Taylor

    2011-01-01

    Communications Infrastructure The 55 CMS Centres worldwide are well used by physicists working on remote CMS shifts, Computing operations, data quality monitoring, data analysis and outreach. The CMS Centre@CERN in Meyrin is particularly busy at the moment, hosting about 50 physicists taking part in the heavy-ion data-taking and analysis. Three new CMS meeting room will be equipped for videoconferencing in early 2012: 40/5B-08, 42/R-031, and 28/S-029. The CMS-TV service showing LHC Page 1, CMS Page 1, etc. (http://cmsdoc.cern.ch/cmscc/projector/index.jsp) is now also available for mobile devices: http://cern.ch/mcmstv. Figure 12: Screenshots of CMS-TV for mobile devices Information Systems CMS has a new web site: (http://cern.ch/cms) using a modern web Content Management System to ensure content and links are managed and updated easily and coherently. It covers all CMS sub-projects and groups, replacing the iCMS internal pages. It also incorporates the existing CMS public web site (http:/...

  16. COMMUNICATIONS GROUP

    CERN Multimedia

    L. Taylor

    2012-01-01

      Outreach and Education We are fortunate that our research has captured the public imagination, even though this inevitably puts us under the global media spotlight, as we saw with the Higgs seminar at CERN in December, which had 110,000 distinct webcast viewers. The media interest was huge with 71 media organisations registering to come to CERN to cover the Higgs seminar, which was followed by a press briefing with the DG and Spokespersons. This event resulted in about 2,000 generally positive stories in the global media. For this seminar, the CMS Communications Group prepared up-to-date news and public material, including links to the CMS results, animations and event displays [http://cern.ch/go/Ch8thttp://cern.ch/go/Ch8t]. There were 44,000 page-views on the CMS public website, with the Higgs news article being by far the most popular item. CMS event displays from iSpy are fast becoming the iconic media images, featuring on numerous major news outlets (BBC, CNN, MSN...) as well as in the sci...

  17. A cell-cell signaling sensor is required for virulence and insect transmission of Xylella fastidiosa.

    Science.gov (United States)

    Chatterjee, Subhadeep; Wistrom, Christina; Lindow, Steven E

    2008-02-19

    Cell-cell signaling in Xylella fastidiosa, a xylem-colonizing plant pathogenic bacterium, mediated by a fatty acid Diffusible Signaling Factor (DSF), is required to colonize insect vectors and to suppress virulence to grape. Here, we show that a hybrid two-component regulatory protein RpfC is involved in negative regulation of DSF synthesis by RpfF in X. fastidiosa. X. fastidiosa rpfC mutants hyperexpress rpfF and overproduce DSF and are deficient in virulence and movement in the xylem vessels of grape. The expression of the genes encoding the adhesins FimA, HxfA, and HxfB is much higher in rpfC mutants, which also exhibit a hyperattachment phenotype in culture that is associated with their inability to migrate in xylem vessels and cause disease. rpfF mutants deficient in DSF production have the opposite phenotypes for all of these traits. RpfC is also involved in the regulation of other signaling components including rpfG, rpfB, a GGDEF domain protein that may be involved in intracellular signaling by modulating the levels of cyclic-di-GMP, and the virulence factors tolC and pglA required for disease. rpfC mutants are able to colonize the mouthparts of insect vectors and wild-type strains but are not transmitted as efficiently to new host plants, apparently because of their high levels of adhesiveness. Because of the conflicting contributions of adhesiveness and other traits to movement within plants and vectoring to new host plants, X. fastidiosa apparently coordinates these traits in a population-size-dependent fashion involving accumulation of DSF.

  18. Sulforaphane inhibits osteoclast differentiation by suppressing the cell-cell fusion molecules DC-STAMP and OC-STAMP

    International Nuclear Information System (INIS)

    Takagi, Tomohiro; Inoue, Hirofumi; Takahashi, Nobuyuki; Katsumata-Tsuboi, Rie; Uehara, Mariko

    2017-01-01

    Sulforaphane (SFN), a kind of isothiocyanate, is derived from broccoli sprouts. It has anti-tumor, anti-inflammatory, and anti-oxidation activity. The molecular function of SFN in the inhibition of osteoclast differentiation is not well-documented. In this study, we assessed the effect of SFN on osteoclast differentiation in vitro. SFN inhibited osteoclast differentiation in both bone marrow cells and RAW264.7 cells. Key molecules involved in the inhibitory effects of SFN on osteoclast differentiation were determined using a microarray analysis, which showed that SFN inhibits osteoclast-associated genes, such as osteoclast-associated receptor (OSCAR), nuclear factor of activated T cells cytoplasmic-1, tartrate-resistant acid phosphatase, and cathepsin K. Moreover, the mRNA expression levels of the cell-cell fusion molecules dendritic cell specific transmembrane protein (DC-STAMP) and osteoclast stimulatory transmembrane protein (OC-STAMP) were strongly suppressed in cells treated with SFN. Furthermore, SFN increased the phosphorylation of signal transducer and activator of transcription 1 (STAT1), a regulator of macrophage and osteoclast cell fusion. Thus, our data suggested that SFN significantly inhibits the cell-cell fusion molecules DC-STAMP and OC-STAMP by inducing the phosphorylation of STAT1 (Tyr701), which might be regulated by interactions with OSCAR. - Highlights: • Sulforaphane inhibited osteoclast differentiation and osteoclast cell-fusion. • Sulforaphane suppressed not only NFATc1, but also cell-cell fusion molecules, DC-STAMP and OC-STAMP. • Sulforaphane decreased multinucleated osteoclasts, whereas increased mono-nucleated osteoclasts. • Sulforaphane inhibits the cell-cell fusion by inducing the phosphorylation of STAT1 (Tyr701).

  19. Seeing and believing: recent advances in imaging cell-cell interactions [v1; ref status: indexed, http://f1000r.es/5br

    Directory of Open Access Journals (Sweden)

    Alpha S. Yap

    2015-07-01

    Full Text Available Advances in cell and developmental biology have often been closely linked to advances in our ability to visualize structure and function at many length and time scales. In this review, we discuss how new imaging technologies and new reagents have provided novel insights into the biology of cadherin-based cell-cell junctions. We focus on three developments: the application of super-resolution optical technologies to characterize the nanoscale organization of cadherins at cell-cell contacts, new approaches to interrogate the mechanical forces that act upon junctions, and advances in electron microscopy which have the potential to transform our understanding of cell-cell junctions.

  20. Evaluating Internal Communication: The ICA Communication Audit.

    Science.gov (United States)

    Goldhaber, Gerald M.

    1978-01-01

    The ICA Communication Audit is described in detail as an effective measurement procedure that can help an academic institution to evaluate its internal communication system. Tools, computer programs, analysis, and feedback procedures are described and illustrated. (JMF)

  1. Communication and Alzheimer's

    Science.gov (United States)

    ... We will not sell or share your name. Communication and Alzheimer's Tweet Bookmark this page | Email | Print ... stage Communication in the late stage Changes in communication In addition to changes in the brain caused ...

  2. Communication in organization

    OpenAIRE

    Zajíc, Jaroslav

    2009-01-01

    Communication is one of the most discussed themes of today and its significance is ever growing. Most often, communication is divided in verbal and nonverbal. It depends if the content of the communicated message is put across in words or not. Every person uses his or her communication style in the contact with others which is different in each situation. The art of communication is the ground not only in everyday life but also in employment. Every organization is a place where communication ...

  3. Role of Cell-Cell bond for the viability and the function of vascular smooth muscle cells

    Directory of Open Access Journals (Sweden)

    M. Mura

    2010-01-01

    Full Text Available Vascular smooth muscle cell (VSMC viability and homeostasis is regulated by cell-matrix and cell-cell contact: disruption of these interactions are responsible of a switch from a mature to a high proliferative phenotype. VSMCs migration, rate of growth and apoptosis, and the extent of their extracellular matrix (ECM deposition can be also modulated by proatherogenic peptides. Among them, ATII induces the transactivation of IGF I R, which, together with the binding protein IGFBP3, represents a determinant of cell survival, growth and proliferation. Aim of our in vitro study was to verify the role of elective cell-cell bond in moulating the response to ATII. Thus, we evaluated viability, proliferation, IGFIR, IGFBP3 expression and the long term survival and production of ECM in a provisional tissue. A7r5 cell-line was used in adherent cultures or incubated in agarose-coated culture plates to inhibit cell-matrix interactions. Cells, treated or not with ATII 100 nM, were evaluated for apoptosis rate, cell cycle, IGFIR and IGFBP3 protei expression. Fibrin provisional tissue was developed polymerizing a fibrin solution. cantaining A7r5 cells with thrombin. Histological stainings for ECM components were performed on sections of prvisional tissue. An exclusive cell-cell contact resulted to monolayer cell cultures. ATII did not affect the cell survival in both culture conditions, but promoted a 10% decrease in "S" phase and an increases IGFIR expression only in adherent cells. while suspended cell aggregates were resistant to ATII administration; IGFBP3 was reduced both in ATII treated adherent cells and in floating clustered cells, irrespective of the treatmentn. VSMC conditioning in agarose-coated plates before seeding in fibrin provisional matrix reduced, but not abolished, the cell ability to colonize the clot and to produce ECM. This study demonstrates that the elective cell-cell contact induces a quiescent status in cells lacking of cell

  4. Intervehicle Communication Research – Communication Scenarios

    Directory of Open Access Journals (Sweden)

    Šarūnas Stanaitis

    2011-03-01

    Full Text Available Recently intervehicle communications are attracting much attention from industry and academia. Upcoming standard for intervehicle communication IEEE 802.11p, known as Wireless Access in Vehicular Environments (WAVE, is still in its draft stage, but already coming into final standardization phase. Problematic, regarding mobile WAVE nodes, are described in several articles, simulations prepared and experiments done. But most of these works do not consider possible maximal communication load. This paper presents intervehicle communication scenario in respect to radio communications, mobility and other aspects of vehicular environments.Article in English

  5. Proline-rich tyrosine kinase 2 (Pyk2) mediates vascular endothelial-cadherin-based cell-cell adhesion by regulating beta-catenin tyrosine phosphorylation

    NARCIS (Netherlands)

    van Buul, Jaap D.; Anthony, Eloise C.; Fernandez-Borja, Mar; Burridge, Keith; Hordijk, Peter L.

    2005-01-01

    Vascular endothelial-cadherin (VE-cadherin) controls endothelial cell-cell adhesion and preserves endothelial integrity. In order to maintain endothelial barrier function, VE-cadherin function is tightly regulated through mechanisms that involve protein phosphorylation and cytoskeletal dynamics.

  6. O ambiente e o papo: comparações internacionais e tipologia das redes verbais nas organizações Environment and chatter: international comparisons of verbal networks in organizations

    Directory of Open Access Journals (Sweden)

    Reed Elliot Nelson

    2007-01-01

    Full Text Available Uma longa tradição de pesquisa afirma que, nos ambientes mais dinâmicos, as organizações necessitam de formas mais "orgânicas", que facilitem a comunicação e a coordenação entre diversas funções e unidades. O crescimento das empresas, associado à diversificação de produtos e à internacionalização, aumenta muito a complexidade do processo gerencial, que não pode depender somente das interfaces formais. As organizações informais, de um lado, podem complementar as deficiências da estrutura formal, ou podem produzir disfunções que levarão a conflitos e desvios dos objetivos e estratégias. Este artigo consiste num estudo das redes sociais verbais de 66 empresas localizadas em vários ambientes industriais no Brasil e nos Estados Unidos, no qual foram identificados três tipos básicos de redes verbais, caracterizadas por diferentes níveis de densidade, faccionalismo e predominância de contatos "fortes". Os três tipos, por sua vez, parecem estar relacionados com o ambiente industrial em que a firma está inserida. As empresas localizadas em ambientes de alta munificência, porém de alta concorrência, dispunham de redes de alta densidade e baixo faccionalismo, com muitos contatos fracos. Em contrapartida, as empresas localizadas em ambientes de estagnação tinham redes de baixa densidade, alto faccionalismo e muitos contatos fortes. Neste artigo, discutimos as implicações desse resultado para a relação empresa-ambiente.A long tradition of research affirms that in the most dynamic environments, organizations need a more "organic" behavior to facilitate communication and coordination between managerial functions and organizational units. Growth of companies, together with product diversification and internationalization, has substantially increased the complexity of management, where only formal interfaces have become insufficient. Informal organization may correct inefficiencies of the formal structure but may also

  7. HAb18G/CD147 cell-cell contacts confer resistance of a HEK293 subpopulation to anoikis in an E-cadherin-dependent manner

    Directory of Open Access Journals (Sweden)

    Zhu Ping

    2010-04-01

    Full Text Available Abstract Background Acquisition of resistance to "anoikis" facilitates the survival of cells under independent matrix-deficient conditions, such as cells in tumor progression and the production of suspension culture cells for biomedical engineering. There is evidence suggesting that CD147, an adhesion molecule associated with survival of cells in tumor metastasis and cell-cell contacts, plays an important role in resistance to anoikis. However, information regarding the functions of CD147 in mediating cell-cell contacts and anoikis-resistance remains limited and even self-contradictory. Results An anoikis-resistant clone (HEK293ar, derived from anoikis-sensitive parental Human Embryonic Kidney 293 cells, survived anoikis by the formation of cell-cell contacts. The expression of HAb18G/CD147 (a member of the CD147 family was upregulated and the protein was located at cell-cell junctions. Upregulation of HAb18G/CD147 in suspended HEK293ar cells suppressed anoikis by mediating the formation of cell-cell adhesions. Anoikis resistance in HEK293ar cells also required E-cadherin-mediated cell-cell contacts. Knock-down of HAb18G/CD147 and E-cadherin inhibited cell-cell contacts formation and increased anoikis sensitivity respectively. When HAb18G/CD147 was downregulated, E-cadherin expression in HEK293ar cells was significantly suppressed; however, knockdown of E-cadherin by E-cadherin siRNA or blocking of E-cadherin binding activity with a specific antibody and EDTA had no significant effect on HAb18G/CD147 expression. Finally, pretreatment with LY294002, a phosphoinositide 3-kinase (PI3K/AKT inhibitor, disrupted cell-cell contacts and decreased cell number, but this was not the case in cells treated with the extracellular signal-regulated kinase (ERK inhibitor PD98059. Conclusions Our results provide new evidence that HAb18G/CD147-mediated cell-cell contact confers anoikis resistance in an E-cadherin-dependent manner; and cell-cell contact mediated

  8. Proactive Parent Communication.

    Science.gov (United States)

    Babcock, Sharel; Backlund, Judy

    2001-01-01

    Presents examples of teacher-parent interactions designed to help teachers communicate with parents. The scenarios involve a teacher communicating with parents about a struggling student, a teacher communicating with parents about a student's behavior problems, and a teacher attempting to communicate with a confrontational parent. Teacher prompts…

  9. Future of wireless communication

    Energy Technology Data Exchange (ETDEWEB)

    Barker, M

    1996-12-31

    This document reproduces slides from a conference presentation giving an overview of current and upcoming wireless communication methods of interest to Canadian electric utilities. Both voice and data communication methods are considered, including cellular telephone, satellite communications, personal communication services, regulated licensed arrowband data systems, and integrated services.

  10. Internet-Based Communication

    Science.gov (United States)

    Gernsbacher, Morton Ann

    2014-01-01

    Google the question, "How is the Internet changing the way we communicate?," and you will find no shortage of opinions, or fears, about the Internet altering the way we communicate. Although the Internet is not necessarily making communication briefer (neither is the Internet making communication less formal), the Internet is manifesting…

  11. Communications device identification methods, communications methods, wireless communications readers, wireless communications systems, and articles of manufacture

    Science.gov (United States)

    Steele, Kerry D [Kennewick, WA; Anderson, Gordon A [Benton City, WA; Gilbert, Ronald W [Morgan Hill, CA

    2011-02-01

    Communications device identification methods, communications methods, wireless communications readers, wireless communications systems, and articles of manufacture are described. In one aspect, a communications device identification method includes providing identification information regarding a group of wireless identification devices within a wireless communications range of a reader, using the provided identification information, selecting one of a plurality of different search procedures for identifying unidentified ones of the wireless identification devices within the wireless communications range, and identifying at least some of the unidentified ones of the wireless identification devices using the selected one of the search procedures.

  12. I-centric Communications

    CERN Document Server

    Arbanowski, S; Steglich, S; Popescu-Zeletin, R

    2001-01-01

    During the last years, a variety of concepts for service integration and corresponding systems have gained momentum. On the one hand, they aim for the interworking and integration of classical telecommunications and data communications services. On the other hand, they are focusing on universal service access from a variety of end user systems. Looking at humans' communication behavior and communication space, it is obvious that human beings interact frequently in a set of contexts in their environment (communication space). Following this view, we want to build communication systems on the analysis of the individual communication spaces. The results are communication systems adapted to the specific demands of each individual. The authors introduce I-centric Communication Systems, an approach to design communication systems which adapt to the individual communication space and individual environment and situation. In this context "I" means I, or individual, "Centric" means adaptable to I requirements and a ce...

  13. Effective communication with seniors

    OpenAIRE

    PONCAROVÁ, Ester

    2008-01-01

    My bachelor thesis is called "The Effective Communication With Seniors". The aim of this thesis is to describe communication, its various kinds and the basic principles of the effective communication. I will also describe the communication with seniors suffering from dementia. Another aim of this thesis is to find out whether workers in the senior houses know and use the principles of the effective communication.

  14. Trends in communications satellites

    CERN Document Server

    Curtin, Denis J

    1979-01-01

    Trends in Communications Satellites offers a comprehensive look at trends and advances in satellite communications, including experimental ones such as NASA satellites and those jointly developed by France and Germany. The economic aspects of communications satellites are also examined. This book consists of 16 chapters and begins with a discussion on the fundamentals of electrical communications and their application to space communications, including spacecraft, earth stations, and orbit and wavelength utilization. The next section demonstrates how successful commercial satellite communicati

  15. Direct Communication Systems

    OpenAIRE

    Krajačić, Ivan

    2016-01-01

    Today we use numerous methods of direct communications, for which we use a technical term Unified Communications. It is almost impossible to imagine the business world today without Unified Communications, which are improving productivity and reducing costs. The goal of using Unified Communications is to ensure a consistent user experience at any location and any device. Skype for Business, a Microsoft product, is one of the solutions for Unified Communications and is described in this thesis...

  16. Newnes communications technology handbook

    CERN Document Server

    Lewis, Geoff

    1994-01-01

    Newnes Communications Technology Handbook provides a discussion on different topics relevant to communications technology. The book is comprised of 39 chapters that tackle a wide variety of concern in communications technology. The coverage of the text includes technologies, such as analog digital communications systems, radio frequency receiver, and satellite systems. The book also discusses some methods and techniques used in communications technology, including mixer signal processing, modulation and demodulation, and spread spectrum techniques. The text will be of great use to engineers, t

  17. Handbook of Technical Communication

    OpenAIRE

    Mehler , Alexander; Romary , Laurent; Gibbon , Dafydd

    2012-01-01

    International audience; The handbook "Technical Communication" brings together a variety of topics which range from the role of technical media in human communication to the linguistic, multimodal enhancement of present-day technologies. It covers the area of computer-mediated text, voice and multimedia communication as well as of technical documentation. In doing so, the handbook takes professional and private communication into account. Special emphasis is put on technical communication bas...

  18. Wireless communication technology NFC

    OpenAIRE

    MÁROVÁ, Kateřina

    2014-01-01

    Aim of this bachelor thesis is to handle the issue of new wireless communication technology NFC (Near Field Communication) including a comparison of advantages and disadvantages of NFC with other wireless technologies (Bluetooth, Wi-Fi, etc.). NFC is a technology for wireless communications between different electronic devices, one of which is typically a mobile phone. Near Field Communication allows wireless communication at very short distance by approaching or enclosing two devices and can...

  19. Real-time sensing of epithelial cell-cell and cell-substrate interactions by impedance spectroscopy on porous substrates

    Energy Technology Data Exchange (ETDEWEB)

    Mondal, D.; RoyChaudhuri, C., E-mail: chirosreepram@yahoo.com [Department of Electronics and Telecommunication Engineering, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103 (India); Pal, D. [Department of Aerospace Engineering and Applied Mechanics, Indian Institute of Engineering Science and Technology, Shibpur, Howrah 711103 (India)

    2015-07-28

    Oxidized porous silicon (PS) is a common topographical biocompatible substrate that potentially provides a distinct in vitro environment for better understanding of in vivo behavior. But in the reported studies on oxidized PS, cell-cell and cell-substrate interactions have been detected only by fluorescent labeling. This paper is the first attempt to investigate real-time sensing of these interactions on HaCaT cells by label-free impedance spectroscopy on oxidized PS of two pore diameters (50 and 500 nm). One of the major requirements for successful impedance spectroscopy measurement is to restrict the channeling of electric field lines through the pores. To satisfy this criterion, we have designed the pore depths after analyzing the penetration of the medium by using computational fluid dynamics simulation. A distributed electrical model was also developed for estimating the various cellular attributes by considering a pseudorandom distribution of pores. It is observed from the impedance measurements and from the model that the proliferation rate increases for 50 nm pores but decreases for 500 nm pores compared to that for planar substrates. The rate of decrease in cell substrate separation (h) in the initial stage is more than the rate of increase in cell-cell junction resistance (R{sub b}) corresponding to the initial adhesion phase of cells. It is observed that R{sub b} and h are higher for 50 nm pores than those for planar substrates, corresponding to the fact that substrates more conducive toward cell adhesion encourage cell-cell interactions than direct cell-substrate interactions. Thus, the impedance spectroscopy coupled with the proposed theoretical framework for PS substrates can sense and quantify the cellular interactions.

  20. Real-time sensing of epithelial cell-cell and cell-substrate interactions by impedance spectroscopy on porous substrates

    International Nuclear Information System (INIS)

    Mondal, D.; RoyChaudhuri, C.; Pal, D.

    2015-01-01

    Oxidized porous silicon (PS) is a common topographical biocompatible substrate that potentially provides a distinct in vitro environment for better understanding of in vivo behavior. But in the reported studies on oxidized PS, cell-cell and cell-substrate interactions have been detected only by fluorescent labeling. This paper is the first attempt to investigate real-time sensing of these interactions on HaCaT cells by label-free impedance spectroscopy on oxidized PS of two pore diameters (50 and 500 nm). One of the major requirements for successful impedance spectroscopy measurement is to restrict the channeling of electric field lines through the pores. To satisfy this criterion, we have designed the pore depths after analyzing the penetration of the medium by using computational fluid dynamics simulation. A distributed electrical model was also developed for estimating the various cellular attributes by considering a pseudorandom distribution of pores. It is observed from the impedance measurements and from the model that the proliferation rate increases for 50 nm pores but decreases for 500 nm pores compared to that for planar substrates. The rate of decrease in cell substrate separation (h) in the initial stage is more than the rate of increase in cell-cell junction resistance (R b ) corresponding to the initial adhesion phase of cells. It is observed that R b and h are higher for 50 nm pores than those for planar substrates, corresponding to the fact that substrates more conducive toward cell adhesion encourage cell-cell interactions than direct cell-substrate interactions. Thus, the impedance spectroscopy coupled with the proposed theoretical framework for PS substrates can sense and quantify the cellular interactions

  1. Development and characterization of a Rift Valley fever virus cell-cell fusion assay using alphavirus replicon vectors

    International Nuclear Information System (INIS)

    Filone, Claire Marie; Heise, Mark; Doms, Robert W.; Bertolotti-Ciarlet, Andrea

    2006-01-01

    Rift Valley fever virus (RVFV), a member of the Phlebovirus genus in the Bunyaviridae family, is transmitted by mosquitoes and infects both humans and domestic animals, particularly cattle and sheep. Since primary RVFV strains must be handled in BSL-3+ or BSL-4 facilities, a RVFV cell-cell fusion assay will facilitate the investigation of RVFV glycoprotein function under BSL-2 conditions. As for other members of the Bunyaviridae family, RVFV glycoproteins are targeted to the Golgi, where the virus buds, and are not efficiently delivered to the cell surface. However, overexpression of RVFV glycoproteins using an alphavirus replicon vector resulted in the expression of the glycoproteins on the surface of multiple cell types. Brief treatment of RVFV glycoprotein expressing cells with mildly acidic media (pH 6.2 and below) resulted in rapid and efficient syncytia formation, which we quantified by β-galactosidase α-complementation. Fusion was observed with several cell types, suggesting that the receptor(s) for RVFV is widely expressed or that this acid-dependent virus does not require a specific receptor to mediate cell-cell fusion. Fusion occurred over a broad temperature range, as expected for a virus with both mosquito and mammalian hosts. In contrast to cell fusion mediated by the VSV-G glycoprotein, RVFV glycoprotein-dependent cell fusion could be prevented by treating target cells with trypsin, indicating that one or more proteins (or protein-associated carbohydrate) on the host cell surface are needed to support membrane fusion. The cell-cell fusion assay reported here will make it possible to study the membrane fusion activity of RVFV glycoproteins in a high-throughput format and to screen small molecule inhibitors for the ability to block virus-specific membrane fusion

  2. Detachment of Chain-Forming Neuroblasts by Fyn-Mediated Control of cell-cell Adhesion in the Postnatal Brain.

    Science.gov (United States)

    Fujikake, Kazuma; Sawada, Masato; Hikita, Takao; Seto, Yayoi; Kaneko, Naoko; Herranz-Pérez, Vicente; Dohi, Natsuki; Homma, Natsumi; Osaga, Satoshi; Yanagawa, Yuchio; Akaike, Toshihiro; García-Verdugo, Jose Manuel; Hattori, Mitsuharu; Sobue, Kazuya; Sawamoto, Kazunobu

    2018-05-09

    In the rodent olfactory system, neuroblasts produced in the ventricular-subventricular zone of the postnatal brain migrate tangentially in chain-like cell aggregates toward the olfactory bulb (OB) through the rostral migratory stream (RMS). After reaching the OB, the chains are dissociated and the neuroblasts migrate individually and radially toward their final destination. The cellular and molecular mechanisms controlling cell-cell adhesion during this detachment remain unclear. Here we report that Fyn, a nonreceptor tyrosine kinase, regulates the detachment of neuroblasts from chains in the male and female mouse OB. By performing chemical screening and in vivo loss-of-function and gain-of-function experiments, we found that Fyn promotes somal disengagement from the chains and is involved in neuronal migration from the RMS into the granule cell layer of the OB. Fyn knockdown or Dab1 (disabled-1) deficiency caused p120-catenin to accumulate and adherens junction-like structures to be sustained at the contact sites between neuroblasts. Moreover, a Fyn and N-cadherin double-knockdown experiment indicated that Fyn regulates the N-cadherin-mediated cell adhesion between neuroblasts. These results suggest that the Fyn-mediated control of cell-cell adhesion is critical for the detachment of chain-forming neuroblasts in the postnatal OB. SIGNIFICANCE STATEMENT In the postnatal brain, newly born neurons (neuroblasts) migrate in chain-like cell aggregates toward their destination, where they are dissociated into individual cells and mature. The cellular and molecular mechanisms controlling the detachment of neuroblasts from chains are not understood. Here we show that Fyn, a nonreceptor tyrosine kinase, promotes the somal detachment of neuroblasts from chains, and that this regulation is critical for the efficient migration of neuroblasts to their destination. We further show that Fyn and Dab1 (disabled-1) decrease the cell-cell adhesion between chain-forming neuroblasts

  3. Pseudo-communication vs Quasi-communication

    Directory of Open Access Journals (Sweden)

    Елена Константиновна Черничкина

    2016-12-01

    Full Text Available The article is devoted to the analysis of such specific forms of human interaction as quasi- and pseudo-communication. The authors specify the terms which sometimes are used interchangeably. The aim of the conducted research is to find out and demonstrate existing differences and similarities of these communicative phenomena on the basis of theoretical and empirical analysis of the research material in the Russian and English languages. The authors describe communicative features of these phenomena and consider the reasons for such forms of communication and their increased use at present. The research material is represented fiction extracts, film scripts, jokes, print media, a collection of oral speech records both in Russian and English. The authors make use of the following research methods: definitional analysis (to define the terminology of the research, the method of linguistic observation and introspection (to select the communicative situations, the descriptive-analytical method and the method of comparative analysis (to identify similarities and differences of the target phenomena, and the conversational analysis method (to view productivity and effectiveness of a dialogue, etc. The classification of possible forms of their existence in different discourses is suggested. The authors assume that both pseudo- and quasi-communication are characterized as fictitious forms of human interaction with some noticeable violation of the basic communicative model. Pseudo-communication suffers from the discrepancy of the meaning of a coded and decoded message. The authors put forward the main parameters of scientific classification of it as follows: adequate understanding, intentionality, and the stage of communicative action where the failure takes place. At the same time they stress the necessity to distinguish the cases of pseudo talks from phatic and indirect communication. Quasi-communcation is marked by the lack of a real partner and hence

  4. Phenotype overlap in Xylella fastidiosa is controlled by the cyclic di-GMP phosphodiesterase Eal in response to antibiotic exposure and diffusible signal factor-mediated cell-cell signaling.

    Science.gov (United States)

    de Souza, Alessandra A; Ionescu, Michael; Baccari, Clelia; da Silva, Aline M; Lindow, Steven E

    2013-06-01

    Eal is an EAL domain protein in Xylella fastidiosa homologous to one involved in resistance to tobramycin in Pseudomonas aeruginosa. EAL and HD-GYP domain proteins are implicated in the hydrolysis of the secondary messenger bis-(3'-5')-cyclic dimeric GMP (cyclic di-GMP). Cell density-dependent communication mediated by a Diffusible Signal Factor (DSF) also modulates cyclic di-GMP levels in X. fastidiosa, thereby controlling the expression of virulence genes and genes involved in insect transmission. The possible linkage of Eal to both extrinsic factors such as antibiotics and intrinsic factors such as quorum sensing, and whether both affect virulence, was thus addressed. Expression of eal was induced by subinhibitory concentrations of tobramycin, and an eal deletion mutant was more susceptible to this antibiotic than the wild-type strain and exhibited phenotypes similar to those of an rpfF deletion mutant blocked in DSF production, such as hypermotility, reduced biofilm formation, and hypervirulence to grape. Consistent with that, the rpfF mutant was more susceptible than the wild-type strain to tobramycin. Therefore, we propose that cell-cell communication and antibiotic stress can apparently lead to similar modulations of cyclic di-GMP in X. fastidiosa, resulting in similar phenotypes. However, the effect of cell density is dominant compared to that of antibiotic stress, since eal is suppressed by RpfF, which may prevent inappropriate behavioral changes in response to antibiotic stress when DSF accumulates.

  5. Improving Pathologists' Communication Skills.

    Science.gov (United States)

    Dintzis, Suzanne

    2016-08-01

    The 2015 Institute of Medicine report on diagnostic error has placed a national spotlight on the importance of improving communication among clinicians and between clinicians and patients [1]. The report emphasizes the critical role that communication plays in patient safety and outlines ways that pathologists can support this process. Despite recognition of communication as an essential element in patient care, pathologists currently undergo limited (if any) formal training in communication skills. To address this gap, we at the University of Washington Medical Center developed communication training with the goal of establishing best practice procedures for effective pathology communication. The course includes lectures, role playing, and simulated clinician-pathologist interactions for training and evaluation of pathology communication performance. Providing communication training can help create reliable communication pathways that anticipate and address potential barriers and errors before they happen. © 2016 American Medical Association. All Rights Reserved.

  6. Digital Marketing Communication

    OpenAIRE

    Margherita Corniani

    2006-01-01

    Digital marketing communication is directed to profiled targets, which are active in the communication process. Every communication flow can ask for an information answer from the market. This opportunity grants immediate feed-backs and feed-forwards, so that digital communication can be easily and cheaply measured; digital communication flows are diffused at costs that are getting lower and lower, but it asks specialized and deep competences to communication managers. The ease in the flowing...

  7. Energy and scientific communication

    Science.gov (United States)

    De Sanctis, E.

    2013-06-01

    Energy communication is a paradigmatic case of scientific communication. It is particularly important today, when the world is confronted with a number of immediate, urgent problems. Science communication has become a real duty and a big challenge for scientists. It serves to create and foster a climate of reciprocal knowledge and trust between science and society, and to establish a good level of interest and enthusiasm for research. For an effective communication it is important to establish an open dialogue with the audience, and a close collaboration among scientists and science communicators. An international collaboration in energy communication is appropriate to better support international and interdisciplinary research and projects.

  8. Localization of a region in the fusion protein of avian metapneumovirus that modulates cell-cell fusion.

    Science.gov (United States)

    Wei, Yongwei; Feng, Kurtis; Yao, Xiangjie; Cai, Hui; Li, Junan; Mirza, Anne M; Iorio, Ronald M; Li, Jianrong

    2012-11-01

    The genus Metapneumovirus within the subfamily Pneumovirinae of the family Paramyxoviridae includes two members, human metapneumovirus (hMPV) and avian metapneumovirus (aMPV), causing respiratory tract infections in humans and birds, respectively. Paramyxoviruses enter host cells by fusing the viral envelope with a host cell membrane. Membrane fusion of hMPV appears to be unique, in that fusion of some hMPV strains requires low pH. Here, we show that the fusion (F) proteins of aMPV promote fusion in the absence of the attachment protein and low pH is not required. Furthermore, there are notable differences in cell-cell fusion among aMPV subtypes. Trypsin was required for cell-cell fusion induced by subtype B but not subtypes A and C. The F protein of aMPV subtype A was highly fusogenic, whereas those from subtypes B and C were not. By construction and evaluation of chimeric F proteins composed of domains from the F proteins of subtypes A and B, we localized a region composed of amino acid residues 170 to 338 in the F protein that is responsible for the hyperfusogenic phenotype of the F from subtype A. Further mutagenesis analysis revealed that residues R295, G297, and K323 in this region collectively contributed to the hyperfusogenicity. Taken together, we have identified a region in the aMPV F protein that modulates the extent of membrane fusion. A model for fusion consistent with these data is presented.

  9. Flagellar membrane fusion and protein exchange in trypanosomes; a new form of cell-cell communication? [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Simon Imhof

    2016-04-01

    Full Text Available Diverse structures facilitate direct exchange of proteins between cells, including plasmadesmata in plants and tunnelling nanotubes in bacteria and higher eukaryotes.  Here we describe a new mechanism of protein transfer, flagellar membrane fusion, in the unicellular parasite Trypanosoma brucei. When fluorescently tagged trypanosomes were co-cultured, a small proportion of double-positive cells were observed. The formation of double-positive cells was dependent on the presence of extracellular calcium and was enhanced by placing cells in medium supplemented with fresh bovine serum. Time-lapse microscopy revealed that double-positive cells arose by bidirectional protein exchange in the absence of nuclear transfer.  Furthermore, super-resolution microscopy showed that this process occurred in ≤1 minute, the limit of temporal resolution in these experiments. Both cytoplasmic and membrane proteins could be transferred provided they gained access to the flagellum. Intriguingly, a component of the RNAi machinery (Argonaute was able to move between cells, raising the possibility that small interfering RNAs are transported as cargo. Transmission electron microscopy showed that shared flagella contained two axonemes and two paraflagellar rods bounded by a single membrane. In some cases flagellar fusion was partial and interactions between cells were transient. In other cases fusion occurred along the entire length of the flagellum, was stable for several hours and might be irreversible. Fusion did not appear to be deleterious for cell function: paired cells were motile and could give rise to progeny while fused. The motile flagella of unicellular organisms are related to the sensory cilia of higher eukaryotes, raising the possibility that protein transfer between cells via cilia or flagella occurs more widely in nature.

  10. Communicating with Professionals

    Medline Plus

    Full Text Available ... Disease Venous Thromboembolism Aortic Aneurysm More Communicating with Professionals Updated:Mar 8,2018 After a cardiac event ... shorter and more rushed than you (or your professionals) want. Simple communication skills can help you get ...

  11. Communicating with Professionals

    Medline Plus

    Full Text Available ... than you (or your professionals) want. Simple communication skills can help you get what you need – over ... the hospital or during office visits. Good communication skills help you get better results from the time ...

  12. Communicating with Professionals

    Medline Plus

    Full Text Available ... rushed than you (or your professionals) want. Simple communication skills can help you get what you need – ... at the hospital or during office visits. Good communication skills help you get better results from the ...

  13. Communicating with Professionals

    Medline Plus

    Full Text Available ... rushed than you (or your professionals) want. Simple communication skills can help you get what you need – over ... at the hospital or during office visits. Good communication skills help you get better results from the time ...

  14. Communication System and Method

    Science.gov (United States)

    Sanders, Adam M. (Inventor); Strawser, Philip A. (Inventor)

    2014-01-01

    A communication system for communicating over high-latency, low bandwidth networks includes a communications processor configured to receive a collection of data from a local system, and a transceiver in communication with the communications processor. The transceiver is configured to transmit and receive data over a network according to a plurality of communication parameters. The communications processor is configured to divide the collection of data into a plurality of data streams; assign a priority level to each of the respective data streams, where the priority level reflects the criticality of the respective data stream; and modify a communication parameter of at least one of the plurality of data streams according to the priority of the at least one data stream.

  15. Intimacy and Computer Communication.

    Science.gov (United States)

    Robson, Dave; Robson, Maggie

    1998-01-01

    Addresses the relationship between intimacy and communication that is based on computer technology. Discusses definitions of intimacy and the nature of intimate conversations that use computers as a communications medium. Explores implications for counseling. (MKA)

  16. Hookah-Related Twitter Chatter: A Content Analysis.

    Science.gov (United States)

    Krauss, Melissa J; Sowles, Shaina J; Moreno, Megan; Zewdie, Kidist; Grucza, Richard A; Bierut, Laura J; Cavazos-Rehg, Patricia A

    2015-07-30

    Hookah smoking is becoming increasingly popular among young adults and is often perceived as less harmful than cigarette use. Prior studies show that it is common for youth and young adults to network about substance use behaviors on social media. Social media messages about hookah could influence its use among young people. We explored normalization or discouragement of hookah smoking, and other common messages about hookah on Twitter. From the full stream of tweets posted on Twitter from April 12, 2014, to May 10, 2014 (approximately 14.5 billion tweets), all tweets containing the terms hookah, hooka, shisha, or sheesha were collected (n = 358,523). The hookah tweets from Twitter users (tweeters) with high influence and followers were identified (n = 39,824) and a random sample of 5,000 tweets was taken (13% of tweets with high influence and followers). The sample of tweets was qualitatively coded for normalization (ie, makes hookah smoking seem common and normal or portrays positive experiences with smoking hookah) or discouragement of hookah smoking, and other common themes using crowdsourcing. Approximately 87% of the sample of tweets normalized hookah use, and 7% were against hookah or discouraged its use. Nearly half (46%) of tweets that normalized hookah indicated that the tweeter was smoking hookah or wanted to smoke hookah, and 19% were advertisements/promotions for hookah bars or products. Educational campaigns about health harms from hookah use and policy changes regarding smoke-free air laws and tobacco advertising on the Internet may be useful to help offset the influence of pro-hookah messages seen on social media.

  17. The chatter door, designing for in-between spaces

    NARCIS (Netherlands)

    Duel, T.; Levy, P.

    2015-01-01

    The project presented in this paper is part of a broader research addressing in-between spaces and the designing of experiences taking place there. The project focuses on door frames, and inquires the way to improve social interactions taking place 'at the door'. To do so, the approach is structured

  18. Female in-nest chatter song increases predation.

    Science.gov (United States)

    Kleindorfer, Sonia; Evans, Christine; Mahr, Katharina

    2016-01-01

    Female song is an ancestral trait in songbirds, yet extant females generally sing less than males. Here, we examine sex differences in the predation cost of singing behaviour. The superb fairy-wren (Malurus cyaneus) is a Southern Hemisphere songbird; males and females provision the brood and produce solo song year-round. Both sexes had higher song rate during the fertile period and lower song rate during incubation and chick feeding. Females were more likely than males to sing close to or inside the nest. For this reason, female but not male song rate predicted egg and nestling predation. This study identifies a high fitness cost of song when a parent bird attends offspring inside a nest and explains gender differences in singing when there are gender differences in parental care. © 2016 The Author(s).

  19. Female in-nest chatter song increases predation

    OpenAIRE

    Kleindorfer, Sonia; Evans, Christine; Mahr, Katharina

    2016-01-01

    Female song is an ancestral trait in songbirds, yet extant females generally sing less than males. Here, we examine sex differences in the predation cost of singing behaviour. The superb fairy-wren (Malurus cyaneus) is a Southern Hemisphere songbird; males and females provision the brood and produce solo song year-round. Both sexes had higher song rate during the fertile period and lower song rate during incubation and chick feeding. Females were more likely than males to sing close to or ins...

  20. Improving Communication in Design

    DEFF Research Database (Denmark)

    Maier, Anja; Doenmez, Denniz; Hepperle, Clemens

    2011-01-01

    Communication permeates every aspect of an engineer’s work – from clarifying product specifications to shaping social ties. This paper offers an overview of recommendations from literature to improve communication within and among engineering teams. We assume communication problems are often...... of tasks. To improve these factors in order to enable effective communication, this paper collates more than hundred recommendations from journal articles and textbooks published in the fields of engineering design, management science, sociology, and psychology. Recommendations include, for example...

  1. COMMUNICATION - ORGANIZATIONS’ WORK DEVICE

    OpenAIRE

    LAVINIA HULEA

    2010-01-01

    Communication represents a complex process of transmitting messages, owing to which the emitter encodes the information transmitted through a specific channel towards a receiver that will decode it. Owing to communication, organizations transmit to their customers the fact that they are capable of meeting one of their needs, of settling a problem or of offering a profit. Non-verbal and para-verbal communications usually accompany verbal communication. The importance of assimilating the forms ...

  2. Intercultural communication: conceptual delimitations

    Directory of Open Access Journals (Sweden)

    Stela SPÎNU

    2018-06-01

    Full Text Available In an era of interference, intercultural communication is timely and advisable. The article analyzes the relation between communication/ language and culture. Starting from a description of different approaches and models of the concept of culture that have influenced and still influence the intercultural communication, and a description of the linguistic theories regarding the relation between language and culture.

  3. Communicating with Young Children

    OpenAIRE

    Harrelson, Peggy O'Neill, 1947-

    2009-01-01

    Communicating positively with young children helps them develop confidence, feelings of self-worth, and good relationships with others. Adults sometimes have difficulty communicating positively with children when feelings are involved-either their own or the child's. This publication explores ways for parents to improve their communication with children.

  4. Communicative Constitution of Organizations

    DEFF Research Database (Denmark)

    Schoeneborn, Dennis; Vasquez, Consuelo

    2017-01-01

    The notion of the communicative constitution of organizations (CCO) is at the center of a growing theoretical development within organizational communication studies. CCO scholarship is based on the idea that organization emerges in and is sustained and transformed by communication. This entry...

  5. Terrorism as Communication.

    Science.gov (United States)

    Decker, Warren; Rainey, Daniel

    Terrorism has become not merely a political act, but a carefully designed and rhetorically sophisticated attempt at communication. What role should the communication scholar play in the investigation of terrorism? Specifically, there are six areas within which the communication scholar may actively contribute to an understanding of terrorism as…

  6. IBM 3705 Communications Controller

    CERN Multimedia

    1972-01-01

    The IBM 3705 Communications Controller is a simple computer which attaches to an IBM System/360 or System/370. Its purpose is to connect communication lines to the mainframe channel. It was a first communications controller of the popular IBM 37xx series.

  7. CSR communication: quo vadis?

    NARCIS (Netherlands)

    Golob, U.; Podnar, K.; Elving, W.J.; Ellerup Nielsen, A.; Thomsen, C.; Schultz, F.

    2013-01-01

    Purpose - This paper aims to introduce the special issue on CSR communication attached to the First International CSR Communication Conference held in Amsterdam in October 2011. The aim of the introduction is also to review CSR communication papers published in scholarly journals in order to make a

  8. Communication Games: Participant's Manual.

    Science.gov (United States)

    Krupar, Karen R.

    Using a series of communicational games, the author leads the participant through self-awareness, verbal and nonverbal communication, decision-making, problem-solving, and skills in perception, listening, and small group, organizational, and cultural communications. The thesis behind the book is that model-making, role-playing, or other forms of…

  9. Teamwork and communication.

    Science.gov (United States)

    Pfrimmer, Dale

    2009-07-01

    Effective teamwork and communication is critical to the delivery of safe and reliable patient care. Communication breakdowns account for the overwhelming majority of sentinel events. Effective teamwork and communication can help prevent mistakes and decrease patient risk. The implementation of simple tools and behaviors can greatly enhance patient safety and improve perceptions of teamwork.

  10. Cross-Cultural Communication.

    Science.gov (United States)

    Tannen, Deborah

    A two-part presentation on cross-cultural communication consists of a discussion of cultural differences in interpersonal communication and an article from a Greek English-language publication concerning telephone use skills in a foreign country. Cultural differences in communication are divided into eight types and illustrated: (1) when to talk;…

  11. ORGANIZATIONAL RISK COMMUNICATION

    Science.gov (United States)

    Ris communication tools in organizations differs in several ways from many of tools and techniques developed for public meetings. The traditional view of risk communication seeks to manage the public outrage ssociated with site-based issues. Organizational risk communication seek...

  12. Diagnosing Communication Pathologies.

    Science.gov (United States)

    Mueller, Carol J.

    This paper addresses the concept of the communication audit, i.e., a fact-finding analysis, interpretation, and reporting process that studies the communication philosophy, structure, flow, and practice of the organization. Reasons for doing a communication audit are identified: (1) to uncover information blockages and organizational hindrances;…

  13. Measuring Communication in Parallel Communicating Finite Automata

    Directory of Open Access Journals (Sweden)

    Henning Bordihn

    2014-05-01

    Full Text Available Systems of deterministic finite automata communicating by sending their states upon request are investigated, when the amount of communication is restricted. The computational power and decidability properties are studied for the case of returning centralized systems, when the number of necessary communications during the computations of the system is bounded by a function depending on the length of the input. It is proved that an infinite hierarchy of language families exists, depending on the number of messages sent during their most economical recognitions. Moreover, several properties are shown to be not semi-decidable for the systems under consideration.

  14. Gap-junction-mediated communication in human periodontal ligament cells.

    Science.gov (United States)

    Kato, R; Ishihara, Y; Kawanabe, N; Sumiyoshi, K; Yoshikawa, Y; Nakamura, M; Imai, Y; Yanagita, T; Fukushima, H; Kamioka, H; Takano-Yamamoto, T; Yamashiro, T

    2013-07-01

    Periodontal tissue homeostasis depends on a complex cellular network that conveys cell-cell communication. Gap junctions (GJs), one of the intercellular communication systems, are found between adjacent human periodontal ligament (hPDL) cells; however, the functional GJ coupling between hPDL cells has not yet been elucidated. In this study, we investigated functional gap-junction-mediated intercellular communication in isolated primary hPDL cells. SEM images indicated that the cells were in contact with each other via dendritic processes, and also showed high anti-connexin43 (Cx43) immunoreactivity on these processes. Gap-junctional intercellular communication (GJIC) among hPDL cells was assessed by fluorescence recovery after a photobleaching (FRAP) analysis, which exhibited dye coupling between hPDL cells, and was remarkably down-regulated when the cells were treated with a GJ blocker. Additionally, we examined GJs under hypoxic stress. The fluorescence recovery and expression levels of Cx43 decreased time-dependently under the hypoxic condition. Exposure to GJ inhibitor or hypoxia increased RANKL expression, and decreased OPG expression. This study shows that GJIC is responsible for hPDL cells and that its activity is reduced under hypoxia. This is consistent with the possible role of hPDL cells in regulating the biochemical reactions in response to changes in the hypoxic environment.

  15. Ouabain Increases Gap Junctional Communication in Epithelial Cells

    Directory of Open Access Journals (Sweden)

    Arturo Ponce

    2014-11-01

    Full Text Available Background/Aims: The finding that endogenous ouabain acts as a hormone prompted efforts to elucidate its physiological function. In previous studies, we have shown that 10 nM ouabain (i.e., a concentration within the physiological range modulates cell-cell contacts such as tight junctions and apical/basolateral polarity. In this study, we examined whether 10 nM ouabain affects another important cell-cell feature: gap junction communication (GJC. Methods: We employed two different approaches: 1 analysis of the cell-to-cell diffusion of neurobiotin injected into a particular MDCK cell (epithelial cells from dog kidneys in a confluent monolayer by counting the number of neighboring cells reached by the probe and 2 measurement of the electrical capacitance. Results: We found that 10 nM ouabain increase GJC by 475% within 1 hour. The Na+-K+-ATPase acts as a receptor of ouabain. In previous works we have shown that ouabain activates c-Src and ERK1/2 in 1 hour; in the present study we show that the inhibition of these proteins block the effect of ouabain on GJC. This increase in GJC does not require synthesis of new protein components, because the inhibitors cycloheximide and actinomycin D did not affect this phenomenon. Using silencing assays we also demonstrate that this ouabain-induced enhancement of GJC involves connexins 32 and 43. Conclusion: Ouabain 10 nM increases GJC in MDCK cells.

  16. Embryo-maternal communication

    DEFF Research Database (Denmark)

    Østrup, Esben; Hyttel, Poul; Østrup, Olga

    2011-01-01

    Communication during early pregnancy is essential for successful reproduction. In this review we address the beginning of the communication between mother and developing embryo; including morphological and transcriptional changes in the endometrium as well as epigenetic regulation mechanisms dire...... directing the placentation. An increasing knowledge of the embryo-maternal communication might not only help to improve the fertility of our farm animals but also our understanding of human health and reproduction.......Communication during early pregnancy is essential for successful reproduction. In this review we address the beginning of the communication between mother and developing embryo; including morphological and transcriptional changes in the endometrium as well as epigenetic regulation mechanisms...

  17. Engagement through communication

    DEFF Research Database (Denmark)

    Lykke, Marianne

    2018-01-01

    In this chapter, we work from the assumption that university engagement can be fostered by addressing the dissemination of scientific knowledge as a communication process, and we explore how university engagement can be encouraged through the communication of scientific knowledge to SMEs (small...... and potentials) in relation to scientific knowledge, which must be taken into account in attempts to communicate scientific knowledge to SMEs. Based on this analysis, we discuss solutions and outline some communicative principles that can contribute with a solution-oriented perspective on how communicating...

  18. Data communication equipment

    International Nuclear Information System (INIS)

    Kim, Hak Seon; Lee, Sang Mok

    1998-02-01

    The contents of this book are introduction of data communication on definition, purpose and history, information terminal about data communication system and data transmission system, data transmit equipment of summary, transmission cable, data port, concentrator and front-end processor, audio communication equipment like phones, radio communication equipment of summary on foundation of electromagnetic waves, AM transmitter, AM receiver, FM receiver and FM transmitter, a satellite and mobile communication equipment such as earth station, TT and C and Cellular phone, video telephone and new media apparatus.

  19. Object-oriented communications

    International Nuclear Information System (INIS)

    Chapman, L.J.

    1989-01-01

    OOC is a high-level communications protocol based on the object-oriented paradigm. OOC's syntax, semantics, and pragmatics balance simplicity and expressivity for controls environments. While natural languages are too complex, computer protocols are often insufficiently expressive. An object-oriented communications philosophy provides a base for building the necessary high-level communications primitives like I don't understand and the current value of X is K. OOC is sufficiently flexible to express data acquisition, control requests, alarm messages, and error messages in a straightforward generic way. It can be used in networks, for inter-task communication, and even for intra-task communication

  20. The Trouble With Strategic Communication(s)

    National Research Council Canada - National Science Library

    Murphy, Dennis M

    2008-01-01

    .... There is no overarching U.S. government definition of strategic communication. There is, however, a Department of Defense definition as a result of the most recent Quadrennial Defense Review (QDR...

  1. Crisis Communication Online

    DEFF Research Database (Denmark)

    Utz, Sonja; Schultz, Friederike; Glocka, Sandra

    2013-01-01

    Social media play in today's societies a fundamental role for the negotiation and dynamics of crises. However, classical crisis communication theories neglect the role of the medium and focus mainly on the interplay between crisis type and crisis communication strategy. Building on the recently...... developed “networked crisis communication model” we contrast effects of medium (Facebook vs. Twitter vs. online newspaper) and crisis type (intentional vs. victim) in an online experiment. Using the Fukushima Daiichi nuclear disaster as crisis scenario, we show that medium effects are stronger than...... the effects of crisis type. Crisis communication via social media resulted in a higher reputation and less secondary crisis reactions such as boycotting the company than crisis communication in the newspaper. However, secondary crisis communication, e.g. talking about the crisis communication, was higher...

  2. Human Bond Communication

    DEFF Research Database (Denmark)

    Prasad, Ramjee

    2016-01-01

    Modern dexterous communication technology is progressively enabling humans to communicate their information through them with speech (aural) and media (optical) as underpinning essence. Humans realize this kind of aural and optical information by their optical and auditory senses. However, due...... to certain constraints, the ability to incorporate the other three sensory features namely, olfactory, gustatory, and tactile are still far from reality. Human bond communication is a novel concept that incorporates olfactory, gustatory, and tactile that will allow more expressive and holistic sensory...... information exchange through communication techniques for more human sentiment centric communication. This concept endorses the need of inclusion of other three senses and proposes an innovative approach of holistic communication for future communication network....

  3. Communication, concepts and grounding.

    Science.gov (United States)

    van der Velde, Frank

    2015-02-01

    This article discusses the relation between communication and conceptual grounding. In the brain, neurons, circuits and brain areas are involved in the representation of a concept, grounding it in perception and action. In terms of grounding we can distinguish between communication within the brain and communication between humans or between humans and machines. In the first form of communication, a concept is activated by sensory input. Due to grounding, the information provided by this communication is not just determined by the sensory input but also by the outgoing connection structure of the conceptual representation, which is based on previous experiences and actions. The second form of communication, that between humans or between humans and machines, is influenced by the first form. In particular, a more successful interpersonal communication might require forms of situated cognition and interaction in which the entire representations of grounded concepts are involved. Copyright © 2014 Elsevier Ltd. All rights reserved.

  4. Resilient Communication: A New Crisis Communication Strategy for Homeland Security

    Science.gov (United States)

    2012-03-01

    communication theory. Author, Timothy Coombs , in Ongoing Crisis Communication , discusses the need for a crisis management 10 plan to prepare for potential... COMMUNICATION : A NEW CRISIS COMMUNICATION STRATEGY FOR HOMELAND SECURITY by Sharon L. Watson March 2012 Thesis Advisor: Christopher Bellavita...REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Resilient Communication : A New Crisis Communication

  5. Histological Architecture Underlying Brain-Immune Cell-Cell Interactions and the Cerebral Response to Systemic Inflammation.

    Science.gov (United States)

    Shimada, Atsuyoshi; Hasegawa-Ishii, Sanae

    2017-01-01

    Although the brain is now known to actively interact with the immune system under non-inflammatory conditions, the site of cell-cell interactions between brain parenchymal cells and immune cells has been an open question until recently. Studies by our and other groups have indicated that brain structures such as the leptomeninges, choroid plexus stroma and epithelium, attachments of choroid plexus, vascular endothelial cells, cells of the perivascular space, circumventricular organs, and astrocytic endfeet construct the histological architecture that provides a location for intercellular interactions between bone marrow-derived myeloid lineage cells and brain parenchymal cells under non-inflammatory conditions. This architecture also functions as the interface between the brain and the immune system, through which systemic inflammation-induced molecular events can be relayed to the brain parenchyma at early stages of systemic inflammation during which the blood-brain barrier is relatively preserved. Although brain microglia are well known to be activated by systemic inflammation, the mechanism by which systemic inflammatory challenge and microglial activation are connected has not been well documented. Perturbed brain-immune interaction underlies a wide variety of neurological and psychiatric disorders including ischemic brain injury, status epilepticus, repeated social defeat, and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Proinflammatory status associated with cytokine imbalance is involved in autism spectrum disorders, schizophrenia, and depression. In this article, we propose a mechanism connecting systemic inflammation, brain-immune interface cells, and brain parenchymal cells and discuss the relevance of basic studies of the mechanism to neurological disorders with a special emphasis on sepsis-associated encephalopathy and preterm brain injury.

  6. Localization of a Region in the Fusion Protein of Avian Metapneumovirus That Modulates Cell-Cell Fusion

    Science.gov (United States)

    Wei, Yongwei; Feng, Kurtis; Yao, Xiangjie; Cai, Hui; Li, Junan; Mirza, Anne M.; Iorio, Ronald M.

    2012-01-01

    The genus Metapneumovirus within the subfamily Pneumovirinae of the family Paramyxoviridae includes two members, human metapneumovirus (hMPV) and avian metapneumovirus (aMPV), causing respiratory tract infections in humans and birds, respectively. Paramyxoviruses enter host cells by fusing the viral envelope with a host cell membrane. Membrane fusion of hMPV appears to be unique, in that fusion of some hMPV strains requires low pH. Here, we show that the fusion (F) proteins of aMPV promote fusion in the absence of the attachment protein and low pH is not required. Furthermore, there are notable differences in cell-cell fusion among aMPV subtypes. Trypsin was required for cell-cell fusion induced by subtype B but not subtypes A and C. The F protein of aMPV subtype A was highly fusogenic, whereas those from subtypes B and C were not. By construction and evaluation of chimeric F proteins composed of domains from the F proteins of subtypes A and B, we localized a region composed of amino acid residues 170 to 338 in the F protein that is responsible for the hyperfusogenic phenotype of the F from subtype A. Further mutagenesis analysis revealed that residues R295, G297, and K323 in this region collectively contributed to the hyperfusogenicity. Taken together, we have identified a region in the aMPV F protein that modulates the extent of membrane fusion. A model for fusion consistent with these data is presented. PMID:22915815

  7. Induction of Cell-Cell Fusion by Ebola Virus Glycoprotein: Low pH Is Not a Trigger.

    Directory of Open Access Journals (Sweden)

    Ruben M Markosyan

    2016-01-01

    Full Text Available Ebola virus (EBOV is a highly pathogenic filovirus that causes hemorrhagic fever in humans and animals. Currently, how EBOV fuses its envelope membrane within an endosomal membrane to cause infection is poorly understood. We successfully measure cell-cell fusion mediated by the EBOV fusion protein, GP, assayed by the transfer of both cytoplasmic and membrane dyes. A small molecule fusion inhibitor, a neutralizing antibody, as well as mutations in EBOV GP known to reduce viral infection, all greatly reduce fusion. By monitoring redistribution of small aqueous dyes between cells and by electrical capacitance measurements, we discovered that EBOV GP-mediated fusion pores do not readily enlarge-a marked difference from the behavior of other viral fusion proteins. EBOV GP must be cleaved by late endosome-resident cathepsins B or L in order to become fusion-competent. Cleavage of cell surface-expressed GP appears to occur in endosomes, as evidenced by the fusion block imposed by cathepsin inhibitors, agents that raise endosomal pH, or an inhibitor of anterograde trafficking. Treating effector cells with a recombinant soluble cathepsin B or thermolysin, which cleaves GP into an active form, increases the extent of fusion, suggesting that a fraction of surface-expressed GP is not cleaved. Whereas the rate of fusion is increased by a brief exposure to acidic pH, fusion does occur at neutral pH. Importantly, the extent of fusion is independent of external pH in experiments in which cathepsin activity is blocked and EBOV GP is cleaved by thermolysin. These results imply that low pH promotes fusion through the well-known pH-dependent activity of cathepsins; fusion induced by cleaved EBOV GP is a process that is fundamentally independent of pH. The cell-cell fusion system has revealed some previously unappreciated features of EBOV entry, which could not be readily elucidated in the context of endosomal entry.

  8. Quantum cryptography communication technology

    International Nuclear Information System (INIS)

    Cho, Jai Wan; Choi, Young Soo; Lee, Jae Chul; Choi, Yu Rak; Jung, Gwang Il; Jung, Jong Eun; Hong, Seok Boong; Koo, In Soo

    2007-09-01

    Quantum cryptography communication based on quantum mechanics provides and unconditional security between two users. Even though huge advance has been done since the 1984, having a complete system is still far away. In the case of real quantum cryptography communication systems, an unconditional security level is lowered by the imperfection of the communication unit. It is important to investigate the unconditional security of quantum communication protocols based on these experimental results and implementation examples for the advanced spread all over the world. The Japanese report, titled, 'Investigation report on the worldwide trends of quantum cryptography communications systems' was translated and summarized in this report. An unconditional security theory of the quantum cryptography and real implementation examples in the domestic area are investigated also. The goal of the report is to make quantum cryptography communication more useful and reliable alternative telecommunication infrastructure as the one of the cyber security program of the class 1-E communication system of nuclear power plant. Also another goal of this report is to provide the quantitative decision basis on the quantum cryptography communication when this secure communication system will be used in class 1-E communication channel of the nuclear power plant

  9. Quantum cryptography communication technology

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Jai Wan; Choi, Young Soo; Lee, Jae Chul; Choi, Yu Rak; Jung, Gwang Il; Jung, Jong Eun; Hong, Seok Boong; Koo, In Soo

    2007-09-15

    Quantum cryptography communication based on quantum mechanics provides and unconditional security between two users. Even though huge advance has been done since the 1984, having a complete system is still far away. In the case of real quantum cryptography communication systems, an unconditional security level is lowered by the imperfection of the communication unit. It is important to investigate the unconditional security of quantum communication protocols based on these experimental results and implementation examples for the advanced spread all over the world. The Japanese report, titled, 'Investigation report on the worldwide trends of quantum cryptography communications systems' was translated and summarized in this report. An unconditional security theory of the quantum cryptography and real implementation examples in the domestic area are investigated also. The goal of the report is to make quantum cryptography communication more useful and reliable alternative telecommunication infrastructure as the one of the cyber security program of the class 1-E communication system of nuclear power plant. Also another goal of this report is to provide the quantitative decision basis on the quantum cryptography communication when this secure communication system will be used in class 1-E communication channel of the nuclear power plant.

  10. A rapid co-culture stamping device for studying intercellular communication

    Science.gov (United States)

    Hassanzadeh-Barforoushi, Amin; Shemesh, Jonathan; Farbehi, Nona; Asadnia, Mohsen; Yeoh, Guan Heng; Harvey, Richard P.; Nordon, Robert E.; Warkiani, Majid Ebrahimi

    2016-10-01

    Regulation of tissue development and repair depends on communication between neighbouring cells. Recent advances in cell micro-contact printing and microfluidics have facilitated the in-vitro study of homotypic and heterotypic cell-cell interaction. Nonetheless, these techniques are still complicated to perform and as a result, are seldom used by biologists. We report here development of a temporarily sealed microfluidic stamping device which utilizes a novel valve design for patterning two adherent cell lines with well-defined interlacing configurations to study cell-cell interactions. We demonstrate post-stamping cell viability of >95%, the stamping of multiple adherent cell types, and the ability to control the seeded cell density. We also show viability, proliferation and migration of cultured cells, enabling analysis of co-culture boundary conditions on cell fate. We also developed an in-vitro model of endothelial and cardiac stem cell interactions, which are thought to regulate coronary repair after myocardial injury. The stamp is fabricated using microfabrication techniques, is operated with a lab pipettor and uses very low reagent volumes of 20 μl with cell injection efficiency of >70%. This easy-to-use device provides a general strategy for micro-patterning of multiple cell types and will be important for studying cell-cell interactions in a multitude of applications.

  11. Developing Intercultural Communicative Competence in ELF Communication

    Directory of Open Access Journals (Sweden)

    Lili Cavalheiro

    2015-06-01

    Full Text Available The traditional notion of English as a foreign language solely for communicating with native speakers can no longer be applied in a world that is constantly changing, hence paving the way for an alternative use of the language known as English as a lingua franca. As a result, instead of focusing only on grammatical correctness, research into language pedagogy has also come to recognize the importance of exploring bottom-up learning processes, and developing intercultural communicative competence (ICC and more communicative-based methods. Nowadays, it is essential to acquire the knowledge, skills, attitudes and critical cultural awareness necessary to communicate successfully. To show the importance of integrating ICC in language pedagogy, a recording from the Vienna-Oxford International Corpus of English is analysed here to demonstrate the significance of developing critical awareness as well as several communicative strategies, so that language learners can afterwards have the necessary ICC to interact in today’s multi-lingual/cultural society.

  12. Organizational communication process

    Directory of Open Access Journals (Sweden)

    Kenan Spaho

    2012-12-01

    Full Text Available Managers spend majority of their time communicating in several forms: meeting, face-to –face dis- cussion, letters, emails etc. Also more and more employees realize that communication is a very im- portant part of their work because a lot of their work activities are based on teamwork among workers in different functional groups. This is the reason why communication has become more important in companies. The experience shows that there are significant differences in manners of communication and that it appears to be a very important factor which makes some organizations more successful than others. Communication is the most important for managers because research shows that the spent long period in work time in communication.

  13. Communicating Your Science

    Science.gov (United States)

    Young, C. A.

    2016-12-01

    Effective science communication can open doors, accelerate your career and even make you a better scientist. Part of being an effective and productive scientist means being an effective science communicator. The scientist must communicate their work in talks, posters, peer-reviewed papers, internal reports, proposals as well as to the broader public (including law makers). Despite the importance of communication, it has traditionally not been part of our core training as scientists. Today's science students are beginning to have more opportunities to formally develop their science communication skills. Fortunately, new and even more established scientists have a range of tools and resources at their disposal. In this presentation, we will share some of these resources, share our own experiences utilizing them, and provide some practical tools to improve your own science communication skills.

  14. Exploring Constrained Creative Communication

    DEFF Research Database (Denmark)

    Sørensen, Jannick Kirk

    2017-01-01

    Creative collaboration via online tools offers a less ‘media rich’ exchange of information between participants than face-to-face collaboration. The participants’ freedom to communicate is restricted in means of communication, and rectified in terms of possibilities offered in the interface. How do...... these constrains influence the creative process and the outcome? In order to isolate the communication problem from the interface- and technology problem, we examine via a design game the creative communication on an open-ended task in a highly constrained setting, a design game. Via an experiment the relation...... between communicative constrains and participants’ perception of dialogue and creativity is examined. Four batches of students preparing for forming semester project groups were conducted and documented. Students were asked to create an unspecified object without any exchange of communication except...

  15. Digital Communication and Modulation

    DEFF Research Database (Denmark)

    Sørensen, John Aasted

    2011-01-01

    system. Having passed the course, the student will be able to accomplish the following, within the areas shown below: Model for Communication System. Prepare and explain the functional block in a digital communication system, corresponding to the specific course contents. Model for Communication Channel...... system.   Sessions in class with active participation by the students. The time will be divided between lectures and the students solving problems, including simulating digital communication building blocks in Matlab. Combines lectures and hands-on work. Semester: E2011 Extent: 7.5 ects......, the fundamental principles for modulation and detection in Gaussian noise is treated. This includes the principles for the determination of the bit-error rate for a digital communication system. During the course, a selection of small Matlab exercises are prepared, for simulation of parts of a communication...

  16. Digital Communication and Modulation

    DEFF Research Database (Denmark)

    Sørensen, John Aasted

    2011-01-01

    system. Having passed the course, the student will be able to accomplish the following, within the areas shown below: Model for Communication System. Prepare and explain the functional block in a digital communication system, corresponding to the specific course contents. Model for Communication Channel...... system. Sessions in class with active participation by the students. The time will be divided between lectures and the students solving problems, including simulating digital communication building blocks in Matlab. Combines lectures and hands-on work. Semester: F2011 Extent: 7.5 ects......, the fundamental principles for modulation and detection in Gaussian noise is treated. This includes the principles for the determination of the bit-error rate for a digital communication system. During the course, a selection of small Matlab exercises are prepared, for simulation of parts of a communication...

  17. Communication in nuclear emergency

    International Nuclear Information System (INIS)

    Nozawa, Masao

    1996-01-01

    In order to take protection measures smoothly at the time of emergency in nuclear power stations and others, it is necessary to prepare information communication facilities mutually among disaster prevention organizations including the state and information transmission network for residents in surrounding areas. The matters decided in ''the measures to be taken for the time being for the countermeasures to prevent disaster in nuclear power stations and others'' are shown. In order to avoid the congestion of communication, the exclusively used communication systems are adopted for disaster prevention organizations, in which facsimile is used to transmit graphic information. The data communication circuits for distributing SPEEDI are installed between Science and Technology Agency, Nuclear Power Safety Technology Center and respective prefectures. The routes, means and order of notices must be confirmed beforehand mutually among the related organizations. As to the general communication for disaster countermeasures, the communication systems in ministries and agencies are described. (K.I.)

  18. Green symbiotic cloud communications

    CERN Document Server

    Mustafa, H D; Desai, Uday B; Baveja, Brij Mohan

    2017-01-01

    This book intends to change the perception of modern day telecommunications. Communication systems, usually perceived as “dumb pipes”, carrying information / data from one point to another, are evolved into intelligently communicating smart systems. The book introduces a new field of cloud communications. The concept, theory, and architecture of this new field of cloud communications are discussed. The book lays down nine design postulates that form the basis of the development of a first of its kind cloud communication paradigm entitled Green Symbiotic Cloud Communications or GSCC. The proposed design postulates are formulated in a generic way to form the backbone for development of systems and technologies of the future. The book can be used to develop courses that serve as an essential part of graduate curriculum in computer science and electrical engineering. Such courses can be independent or part of high-level research courses. The book will also be of interest to a wide range of readers including b...

  19. Designing for Networked Communications

    DEFF Research Database (Denmark)

    Designing for Networked Communications: Strategies and Development explains how to plan, use, and understand the products and the dynamic social processes and tasks some of the most vital innovations in the knowledge society depend upon– social as well as technological. Focusing on various forms...... of design, implementation and integration of computer mediated communication, this book bridges the academic fields of computer science and communication studies. Designing for Networked Communications: Strategies and Development uses an interdisciplinary approach, and presents results from recent...... and important research in a variety of forms for networked communications. A constructive and critical view of the interplay between the new electronic and the more conventional modes of communication are utilized, while studies of organizational work practices demonstrate that the use of new technologies...

  20. Organizational communication process

    OpenAIRE

    Kenan Spaho

    2012-01-01

    Managers spend majority of their time communicating in several forms: meeting, face-to –face dis- cussion, letters, emails etc. Also more and more employees realize that communication is a very im- portant part of their work because a lot of their work activities are based on teamwork among workers in different functional groups. This is the reason why communication has become more important in companies. The experience shows that there are significant differences in manners of ...

  1. Digital communication system

    International Nuclear Information System (INIS)

    Union, D.C.

    1980-01-01

    A digital communication system for communicating among two central consoles and a plurality of local controllers, e.g. in a radiation and monitoring system, provides communication between each of the consoles and all of the local controllers via dual paths. Each path is independent of the other and each extends from one of the consoles to all of the local controllers from opposite directions, thereby forming a unique non-continuous loop. (author)

  2. Secure Fiberoptic Communications

    Science.gov (United States)

    Hodara, Henri

    At the heart of our current information explosion is the communication network. Networks are now an intrinsic part of our daily activities, whether they are for Internet business transactions or military communications in Future Combat Systems. Protection of this communication infrastructure is a must. In this article, we discuss two approaches for securing all-optical networks. The first is an optical encryption technique that denies the information to intruders. The second is an authentication scheme capable of detecting and identifying unauthorized users.

  3. Communications and media services

    Science.gov (United States)

    Mcculla, James W.; Kukowski, James F.

    1990-01-01

    NASA's internal and external communication methods are reviewed. NASA information services for the media, for the public, and for employees are discussed. Consideration is given to electron information distribution, the NASA TV-audio system, the NASA broadcast news service, astronaut appearances, technology and information exhibits, speaker services, and NASA news reports for internal communications. Also, the NASA worldwide electronic mail network is described and trends for future NASA communications and media services are outlined.

  4. Communication, ethics and anthropoethics

    OpenAIRE

    Luiz Martins da Silva

    2009-01-01

    The purpose of this article is to dream of – in the sense ofestablishing – the utopian perspective of a scenario that remains utopian but which nonetheless provides the first indications that we may be entering a new paradigm, that of communication-ethics, that is to say, the ethical dimension of communication, which in this case is not restricted to technological advancements but concerns communication with ethics and as ethics, to conclude that without ethics, there is no commun...

  5. Corruption and Organizational Communication

    DEFF Research Database (Denmark)

    Krause Hansen, Hans

    2017-01-01

    , and societal levels, as well as how corruption is and can be responded to through public scandals and more elaborate communicative strategies of corruption control, or anti-corruption. A focus on corruption and corruption control provides organizational communication scholars with entry points to explore...... the powerful communicative dynamics playing out between the local organizational meanings of particular practices and externally imposed definitions of what constitutes appropriate organizational behavior....

  6. Wire communication engineering

    International Nuclear Information System (INIS)

    Son, Byeong Tae

    1997-02-01

    This book describes wire telecommunication engineering/ It is divided into eleven chapter, which deal with Introduction with development of telecommunication, voice and sound wave and communication network, Telegraphy with summary of telegraphy, code of telegraphy, communication speed, morse and telex, Telephone on structure, circuit and image telephone, Traffic on telecommunication traffic, transmission of line about theory, cable line and loaded cable, carrier communication with carrier telegraphy and carrier telephone, optical communication with types, structure, specialty, laser and equipment, DATA, Mobile telecommunication on summary, mobile telephone, radio paging and digital mobile telecommunication, ISDN with channel of ISDN, and service of ISDN, and design of telecommunication.

  7. Mobile communication and intermediality

    DEFF Research Database (Denmark)

    Helles, Rasmus

    2013-01-01

    communicative affordances of mobile devices in order to understand how people choose between them for different purposes. It is argued that mobile communication makes intermediality especially central, as the choice of medium is detached from the location of stationary media and begins to follow the user across......The article argues the importance of intermediality as a concept for research in mobile communication and media. The constant availability of several, partially overlapping channels for communication (texting, calls, email, Facebook, etc.) requires that we adopt an integrated view of the various...

  8. Communicating with Professionals

    Medline Plus

    Full Text Available ... Being Active - FAQs About Physical Activity Managing Your Medicines - Introduction - Taking Control of Your Medicines - Medicine Assistance Programs - Medicine Checklist - Medication Tracker Communicating ...

  9. Networked Constellation Communications Technologies

    Data.gov (United States)

    National Aeronautics and Space Administration — Develop communications architectures and enabling technologies for mission concepts relying on multiple spatially distributed spacecraft to perform coordinated...

  10. The art of communication.

    Science.gov (United States)

    Warnecke, Emma

    2014-03-01

    Effective communication is an essential skill in general practice consultations. The art of communication is the development of effective skills and finding a style of communication that suits the clinician and produces benefits for both patient and doctor. This paper outlines the essential skills required for effective communication with a patient and suggests that clinicians consider this communication as an art that can be developed throughout a medical career. Good communication can improve outcomes for patients and doctors, and deserves equal importance as developing clinical knowledge and procedural skill. The importance of good communication is so critical that Australian guidelines list effective communication as part of the required conduct for all doctors. A therapeutic patient-doctor relationship uses the clinician as a therapeutic intervention and is part of the art of communication. Despite all the technological advances of recent decades, caring, compassionate, healing doctors remain the best therapeutic tool in medicine. The ability of a doctor to provide comfort through their presence and their words is a fundamental component of good medical care.

  11. Improve your communication skills

    CERN Document Server

    Barker, Alan

    2016-01-01

    Excellent communication skills are vital in today's workplace. Whether keeping the interest of a large audience, impressing a potential employer or simply winning the argument at an important meeting, sounding the part is key. This fourth edition of Improve Your Communication Skills is full of practical advice on all aspects of verbal and non-verbal communication. It gives vital tips on improving conversations and building rapport with colleagues, learning the skills of persuasion, and writing effective emails, letters and reports. This editionincludes new information focusing on communicating across borders and virtual teams and a new chapter on managing difficult conversations."

  12. Measurement of communication

    International Nuclear Information System (INIS)

    1998-08-01

    This book is one of series of information communication, which deals with measurement of communication. It is divided into six chapters. The contents are foundation of measurement with classification and principle, Basic measurement on current, voltage, electric resistance, power and impedance, measurement of communication line with way by L3 tester, BW tester and pulse tester, measurement of optical fiber cable of equipment and method, Test and measurement of information communication equipment about test of modulator and use, measurement of cable broadcasting equipment on transmission level and main transmission equipment.

  13. Filaggrin 2 deficiency results in abnormal cell-cell adhesion in the cornified cell layers and causes peeling skin syndrome type A.

    Science.gov (United States)

    Mohamad, Janan; Sarig, Ofer; Godsel, Lisa M; Peled, Alon; Malchin, Natalia; Bochner, Ron; Vodo, Dan; Rabinowitz, Tom; Pavlovsky, Mor; Taiber, Shahar; Fried, Maya; Eskin-Schwartz, Marina; Assi, Siwar; Shomron, Noam; Uitto, Jouni; Koetsier, Jennifer L; Bergman, Reuven; Green, Kathleen J; Sprecher, Eli

    2018-05-11

    Peeling skin syndromes form a large and heterogeneous group of inherited disorders characterized by superficial detachment of the epidermal cornified cell layers, often associated with inflammatory features. Here we report on a consanguineous family featuring non-inflammatory peeling of the skin exacerbated by exposure to heat and mechanical stress. Whole exome sequencing revealed a homozygous nonsense mutation in FLG2, encoding filaggrin 2, which co-segregated with the disease phenotype in the family. The mutation was found to result in decreased FLG2 RNA levels as well almost total absence of filaggrin 2 in the patient epidermis. Filaggrin 2 was found to be expressed throughout the cornified cell layers and to co-localize with corneodesmosin which plays a crucial role in maintaining cell-cell adhesion in this region of the epidermis. Absence of filaggrin 2 in the patient skin was associated with markedly decreased corneodesmosin expression, which may contribute to the peeling phenotype displayed by the patients. Accordingly, using the dispase dissociation assay, we showed that FLG2 down-regulation interferes with keratinocyte cell-cell adhesion. Of particular interest, this effect was aggravated by temperature elevation, consistent with the clinical phenotype. Restoration of CDSN levels by ectopic expression rescued cell-cell adhesion.Taken together, the present data suggest that filaggrin 2 is essential for normal cell-cell adhesion in the cornified cell layers. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  14. Ochratoxim A alters cell adhesion and gap junction intercellular communication in MDCK cells

    International Nuclear Information System (INIS)

    Mally, Angela; Decker, Martina; Bekteshi, Michaela; Dekant, Wolfgang

    2006-01-01

    Ochratoxin A (OTA) is one of the most potent renal carcinogens studied to date, but the mechanism of tumor formation by ochratoxin A remains largely unknown. Cell adhesion and cell-cell communication participate in the regulation of signaling pathways involved in cell proliferation and growth control and it is therefore not surprising that modulation of cell-cell signaling has been implicated in cancer development. Several nephrotoxicants and renal carcinogens have been shown to alter cell-cell signaling by interference with gap junction intercell communication (GJIC) and/or cell adhesion, and the aim of this study was to determine if disruption of cell-cell interactions occurs in kidney epithelial cells in response to OTA treatment. MDCK cells were treated with OTA (0-50 μM) for up to 24 h and gap junction function was analyzed using the scrape-load/dye transfer assay. In addition, expression and intracellular localization of Cx43, E-cadherin and β-catenin were determined by immunoblot and immunofluorescence analysis. A clear decrease in the distance of dye transfer was evident following treatment with OTA at concentrations/incubation times which did not affect cell viability. Consistent with the functional inhibition of GJIC, treatment with OTA resulted in a dose-dependent decrease in Cx43 expression. In contrast to Cx43, OTA did not alter total amount of the adherens junction proteins E-cadherin and β-catenin. Moreover, Western blot analysis of Triton X-100 soluble and insoluble protein fractions did not indicate translocation of cell adhesion molecules from the membrane to the cytoplasm. However, a ∼78 kDa fragment of β-catenin was detected in the detergent soluble fraction, indicating proteolytic cleavage of β-catenin. Immunofluorescence analysis also revealed changes in the pattern of both β-catenin and E-cadherin labeling, suggesting that OTA may alter cell-adhesion. Taken together, these data support the hypothesis that disruption of cell-cell

  15. A yeast pheromone-based inter-species communication system.

    Science.gov (United States)

    Hennig, Stefan; Clemens, André; Rödel, Gerhard; Ostermann, Kai

    2015-02-01

    We report on a pheromone-based inter-species communication system, allowing for a controlled cell-cell communication between the two species Saccharomyces cerevisiae and Schizosaccharomyces pombe as a proof of principle. It exploits the mating response pathways of the two yeast species employing the pheromones, α- or P-factor, as signaling molecules. The authentic and chimeric pheromone-encoding genes were engineered to code for the P-factor in S. cerevisiae and the α-factor in S. pombe. Upon transformation of the respective constructs, cells were enabled to express the mating pheromone of the opposite species. The supernatant of cultures of S. pombe cells expressing α-factor were able to induce a G1 arrest in the cell cycle, a change in morphology to the typical shmoo effect and expression driven by the pheromone-responsive FIG1 promoter in S. cerevisiae. The supernatant of cultures of S. cerevisiae cells expressing P-factor similarly induced cell cycle arrest in G1, an alteration in morphology typical for mating as well as the activation of the pheromone-responsive promoters of the rep1 and sxa2 genes in a pheromone-hypersensitive reporter strain of S. pombe. Apparently, both heterologous pheromones were correctly processed and secreted in an active form by the cells of the other species. Our data clearly show that the species-specific pheromone systems of yeast species can be exploited for a controlled inter-species communication.

  16. Transforming growth factor beta 1 modulates extracellular matrix organization and cell-cell junctional complex formation during in vitro angiogenesis.

    Science.gov (United States)

    Merwin, J R; Anderson, J M; Kocher, O; Van Itallie, C M; Madri, J A

    1990-01-01

    Transforming growth factor-beta 1 (TGF-beta 1) is angiogenic in vivo. In two-dimensional (2-D) culture systems microvascular endothelial cell proliferation is inhibited up to 80% by TGF-beta 1; however, in three-dimensional (3-D) collagen gels TGF-beta 1 is found to have no effect on proliferation while eliciting the formation of calcium and magnesium dependent tube-like structures mimicking angiogenesis. DNA analyses performed on 3-D cell cultures reveal no significant difference in the amount of DNA or cell number in control versus TGF-beta 1 treated cultures. In 2-D cultures TGF-beta 1 is known to increase cellular fibronectin accumulation; however, in 3-D cultures no difference is seen between control and TGF-beta 1 treated cells as established by ELISA testing for type IV collagen, fibronectin, and laminin. In 3-D cultures there is increased synthesis and secretion of type V collagen in both control and TGF-beta 1 treated cultures over 2-D cultures. Even though an equal amount of type V collagen is seen in both 3-D conditions, there is a reorganization of the protein with concentration along an organizing basal lamina in TGF-beta 1 treated cultures. EM morphological analyses on 3-D cultures illustrate quiescent, control cells lacking cell contacts. In contrast, TGF-beta 1 treated cells show increased pseudopod formation, cell-cell contact, and organized basal lamina-like material closely apposed to the "abluminal" plasma membranes. TGF-beta 1 treated cells also appear to form junctional complexes between adjoining cells. Immunofluorescence using specific antibodies to the tight junction protein ZO-1 results in staining at apparent cell-cell junctions in the 3-D cultures. Northern blots of freshly isolated microvascular endothelium, 2-D and 3-D cultures, using cDNA and cRNA probes specific for the ZO-1 tight junction protein, reveal the presence of the 7.8 kb mRNA. Western blots of rat epididymal fat pad endothelial cells (RFC) monolayer lysates probed with

  17. Nonprofit Communications from a Corporate Communications Viewpoint

    Science.gov (United States)

    Cross, Ava

    2006-01-01

    Nonprofit organizations, such as social service agencies, charities, and hospitals, plan and prepare communications that are vital to their missions. Although not corporations, these organizations produce news releases, newsletters, and annual reports that are similar to those created in the corporate sector. In this research project for a course…

  18. Ordinateur et communication (Computer and Communication).

    Science.gov (United States)

    Mangenot, Francois

    1994-01-01

    Because use of computers in second-language classrooms may tend to decrease interpersonal interaction, and therefore communication, ways to promote interaction are offered. These include small group computer projects, and suggestions are made for use with various computer functions and features: tutorials, word processing, voice recording,…

  19. What Makes You Tick? An Empirical Study of Space Science Related Social Media Communications Using Machine Learning

    Science.gov (United States)

    Hwong, Y. L.; Oliver, C.; Van Kranendonk, M. J.

    2016-12-01

    The rise of social media has transformed the way the public engages with scientists and science organisations. `Retweet', `Like', `Share' and `Comment' are a few ways users engage with messages on Twitter and Facebook, two of the most popular social media platforms. Despite the availability of big data from these digital footprints, research into social media science communication is scant. This paper presents the results of an empirical study into the processes and outcomes of space science related social media communications using machine learning. The study is divided into two main parts. The first part is dedicated to the use of supervised learning methods to investigate the features of highly engaging messages., e.g. highly retweeted tweets and shared Facebook posts. It is hypothesised that these messages contain certain psycholinguistic features that are unique to the field of space science. We built a predictive model to forecast the engagement levels of social media posts. By using four feature sets (n-grams, psycholinguistics, grammar and social media), we were able to achieve prediction accuracies in the vicinity of 90% using three supervised learning algorithms (Naive Bayes, linear classifier and decision tree). We conducted the same experiments on social media messages from three other fields (politics, business and non-profit) and discovered several features that are exclusive to space science communications: anger, authenticity, hashtags, visual descriptions and a tentative tone. The second part of the study focuses on the extraction of topics from a corpus of texts using topic modelling. This part of the study is exploratory in nature and uses an unsupervised method called Latent Dirichlet Allocation (LDA) to uncover previously unknown topics within a large body of documents. Preliminary results indicate a strong potential of topic model algorithms to automatically uncover themes hidden within social media chatters on space related issues, with

  20. Netiquette in Electronic Communication

    Directory of Open Access Journals (Sweden)

    Tomáš Kozík

    2014-06-01

    Full Text Available Electronic mail and electronic communications systems are considered significant and effective tools of communication. One of the most widespread electronic communication tools is e - mail communication. In order to avoid misinterpretation of the report on the side of the recipient, it is need to pay attention to the writing of e - mail messages as well as to their content. With the continuous expansion of the use of electronic communication there have gradually developed certain rules of etiquette in electronic communications. The existing rules of the propriety ones are expressed in the term " etiqutte " and are not automatically applied in the new communications environment - media. For electronic communication, the new rules of etiquette have been stabilised into a term NETIQUETTE. The word netiquette was created by combining words NET (net and ETIKETA (a set of rules of social behavior and habits. Netiquette constitutes the rules of the behavior of users on a network. Although the netiquette is merely "an unwritten set of rules", their not using can be understood as a type of disrespect. Analysis of knowledge of domestic and foreign sources as well as results of a survey confirmed the justification of paying attention to the education of individuals in NETIQUETTE, irrespective of the degree of education.

  1. Ionosphere and Radio Communication

    Indian Academy of Sciences (India)

    The upperionosphere is used for radio communication and navigationas it reflects long, medium, as well as short radio waves. Sincesolar radiation is the main cause of the existence of ionosphere,any variation in the radiations can affect the entireradio communication system. This article attempts to brieflyintroduce the ...

  2. Flesh as communication

    DEFF Research Database (Denmark)

    Heinrich, Falk

    2012-01-01

    , action. A correlative bond lies in communication theory as the operational difference between ego and alter-ego. This article investigates the non-semiotic intertwinement of ‘flesh’ in art perception and theory based on communication theory in performance art (body art). The thesis is that ‘flesh...

  3. Business Communication in BELF

    Science.gov (United States)

    Kankaanranta, Anne; Louhiala-Salminen, Leena

    2007-01-01

    The authors' business communication perspective is not in fact that of ESL but rather English as a foreign language (EFL) or, even more so, English as a lingua franca (ELF). To be more specific, they would like to add one more acronym to the list: They teach BELF, by which they refer to ELF for business communication purposes. The authors work as…

  4. Marketing communication in tourism

    OpenAIRE

    Kashkina, Katsiaryna

    2008-01-01

    The aim of this graduation thesis was to analyze some possibilities of marketing communication in tourism. For this analize were chosen travel agencies in Tábor. The partial objects consisted in the analysis of supply of researched travel agencies including their marketing communication. There was found out also demand of products in tourism. After analyses were prepared some recommendations for improvement.

  5. International Communication and Esperanto.

    Science.gov (United States)

    Tonkin, Humphrey

    The author discusses (1) the nature of communication, (2) sociological aspects of the communication problem, and (3) solutions to the language problem that have been tried. He believes that "there is a solution easier and more successful than multilingualism, and less discriminatory than the unilateral imposition of one national language for…

  6. Intracultural Communication: Selected Bibliography.

    Science.gov (United States)

    Byrd, Marquita L.

    The 63 books and journal articles listed in this bibliography address the problem of intracultural communication. A short introduction to the bibliography defines intracultural communication as the creation and sharing of meaning among citizens of the same geo-political system who come from various tributary cultures (groups distinguishable from…

  7. Commercial Radio as Communication.

    Science.gov (United States)

    Rothenbuhler, Eric W.

    1996-01-01

    Compares the day-to-day work routines of commercial radio with the principles of a theoretical communication model. Illuminates peculiarities of the conduct of communication by commercial radio. Discusses the application of theoretical models to the evaluation of practicing institutions. Offers assessments of commercial radio deriving from…

  8. Communication of the popular

    Directory of Open Access Journals (Sweden)

    Božilović Nikola

    2015-01-01

    Full Text Available The article deals with the problems of the communication of popular culture. It considers the more specialized meaning of popular culture, which primarily encompasses the works of artistic forms which have a popular character - easily understandable and entertaining contents and wide audience. The aesthetic communication of the popular through popular literature, film, pop and rock music is examined. The paper is divided into three parts. The first parts deals with the aesthetics of the communication of popular culture. It contains the analysis of the major formal-aesthetic procedures embedded in the creative expression of the popular. In the part which is dedicated to social aspects of the communication of popular art, the author examines the industrial, market and commercial principles upon which this whole culture is based. It is a time of new technologies and mass consumption, which represent, in the words of Eric Hobsbawm, a 'cultural landscape' that has transformed the manner in which a new audience experiences the artistic. Finally, popular culture stars are observed as communicators. The author adds them as a new, even crucial, link in the already known chain of communication comprising the author, the work and the audience. Stars (film, popular music are active factors of communication as well as its bearers. They are the intermediaries through which the audience establishes relationships with the authors (writers, directors, composers and the works in which those stars appear. Stars as 'new Olympians' (Morin are, indeed, another significant category that distinguishes the communication of popular culture.

  9. Communication, concepts and grounding

    NARCIS (Netherlands)

    van der Velde, Frank; van der Velde, F.

    2015-01-01

    This article discusses the relation between communication and conceptual grounding. In the brain, neurons, circuits and brain areas are involved in the representation of a concept, grounding it in perception and action. In terms of grounding we can distinguish between communication within the brain

  10. Information or communication

    DEFF Research Database (Denmark)

    Dahms, Mona-Lisa

    2004-01-01

    The paper describes the development in Tanzania, in terms of information and communication technologies and how these developments have influenced people's daily life.......The paper describes the development in Tanzania, in terms of information and communication technologies and how these developments have influenced people's daily life....

  11. Participatory Development Communication

    International Development Research Centre (IDRC) Digital Library (Canada)

    Training Needs in Participatory Development Communication .... to the development of society (communications in the service of development), ... There are also some definitions that give a more restrictive meaning to the way ...... Although proponents of participation appreciate that there is more good than bad in the ...

  12. Communication Signals in Lizards.

    Science.gov (United States)

    Carpenter, Charles C.

    1983-01-01

    Discusses mechanisms and functional intent of visual communication signals in iguanid/agamid lizards. Demonstrated that lizards communicate with each other by using pushups and head nods and that each species does this in its own way, conveying different types of information. (JN)

  13. Socio-Communication.

    Science.gov (United States)

    Roth, James David

    The focus of this work is the introduction and description of a quasi-new concept called socio-communication. In chapter 1 the term "socio communication" is defined as "human interaction, among and between different classes of people, by means of verbal and nonverbal expression in day-to-day social situations." In chapter 2 social communication…

  14. Mask Phenomenon in Communication

    Institute of Scientific and Technical Information of China (English)

    郎丽璇

    2013-01-01

    People sometimes wear masks. Abusive expression may be used to convey love while polite words can be exchanged among enemies. This essay describes and discusses this special phenomenon in communication and analyzes the elements that con-tribute to the success of a mask communication.

  15. Communication Challenge Softball

    Science.gov (United States)

    Moran, Tom; Vance, Mike

    2005-01-01

    Communication Challenge Softball is a developmentally appropriate game for middle school students. The game allows them to develop new communication skills using American Sign Language (signing). Traditional softball has been a part of physical education for years, and remains a popular sport played by children in community leagues throughout the…

  16. Functional Communication Training

    Science.gov (United States)

    Durand, V. Mark; Moskowitz, Lauren

    2015-01-01

    Thirty years ago, the first experimental demonstration was published showing that educators could improve significant challenging behavior in children with disabilities by replacing these behaviors with forms of communication that served the same purpose, a procedure called functional communication training (FCT). Since the publication of that…

  17. Project Communications Management

    OpenAIRE

    José C. Santiago-Guevara; Mauricio Rojas-Contreras; Luis A. Esteban-Villamizar

    2013-01-01

    This article presents a review in relation to the object of study: Communications Management as an important factor in the management of projects. The review includes the most relevant and most renowned authors in the field of project management, focusing on telecommunications projects, which lets you define a communications management model.

  18. Communication Analysis of Environment.

    Science.gov (United States)

    Malik, M. F.; Thwaites, H. M.

    This textbook was developed for use in a Concordia University (Quebec) course entitled "Communication Analysis of Environment." Designed as a practical application of information theory and cybernetics in the field of communication studies, the course is intended to be a self-instructional process, whereby each student chooses one…

  19. Marxism and Communication.

    Science.gov (United States)

    Daley, Patrick J.; Soloski, John

    Karl Marx and Friedrich Engels had little to say specifically about communication and language, but their works hint at the direction their critique of communication might have taken. Language and consciousness are conditioned by specific means of production and sociopolitical circumstances and are therefore ideological. The domain of ideology…

  20. COMMUNICATIVE LANGUAGE TEACHING

    Directory of Open Access Journals (Sweden)

    Angela JIREGHIE

    2012-06-01

    Full Text Available This paper focuses on the idea of an effective communication between teacher and students aiming to prove that classroom activities maximize opportunities for learners to use target language in a communicative way for meaningful activities. The emphasis lies on meaning (messages they are creating or tasks they are completing rather than form (correctness of language and language structure.

  1. Subliminal communication technology

    Science.gov (United States)

    Various types of subliminal communication devices presently in use, the psychological basis for subliminal technology, and the effectiveness of subliminal communication for therapy are examined as well as potentials for abuse. Social, legal, and ethical aspects are considered with respect to the privacy and autonomy of captive audiences. Implications for the regulation of subliminal techniques are reviewed with application to the various media.

  2. Communication in cartelized industries

    NARCIS (Netherlands)

    van Cayseele, P.J.G.; Camesasca, P.D.

    2010-01-01

    In this article we first survey both the European Commission’s legal standard and economic theory on communication in industries in which a cartel is operating. We notice a strong tension between the per se illegal nature of communication on price and price fixing, considered to be proof of the

  3. Data communications pocket book

    CERN Document Server

    Tooley, Michael

    2014-01-01

    Data Communications Pocket Book, Second Edition presents information relevant to data communication. The book provides tabulated reference materials with a brief description and diagrams. The coverage of the text includes abbreviations, terminal control codes, and conversion tables. The text will be of great use to individuals involved in the interconnection of computer systems.

  4. Communicating research results

    Science.gov (United States)

    Jan Fryk

    1999-01-01

    A research finding is of little value until it is known and applied. Hence) communication of results should be regarded as a natural, integrated part of research) and thus addressed in the research plans from the very beginning. A clearly defined information strategy and operational goals for information activities are needed for successful communication. For maximum...

  5. Communicating the seemingly unintelligible

    DEFF Research Database (Denmark)

    Chimirri, Niklas Alexander

    -communicable to others. Unintelligible imaginations may be grounds for suffering, as an individual’s struggles cannot be communicatively exchanged with others and may therefore never be overcome – one’s sense, so to say, may never be turned into a shareable common sense and consequently never finds its expression...

  6. Reinventing Corporate Communications.

    Science.gov (United States)

    Toth, Elizabeth L.; Trujillo, Nick

    1987-01-01

    Urges a "re-inventing" of corporate communications in today's organizations, and provides information about how corporations can change in new and positive ways during the current "information age." Discusses specific public relations and organizational communication concepts essential for a comprehensive understanding of…

  7. Comparative Political Communication Research

    NARCIS (Netherlands)

    de Vreese, C.H.; Kenski, K.; Jamieson, K.H.

    2017-01-01

    This chapter provides an overview of comparative political communication research (CPCR). CPCR is a growing field since there is wide acknowledgement that many questions are not answered satisfactorily with single case studies. The chapter explains why political communication researchers should care

  8. Essays on Strategic Communication

    NARCIS (Netherlands)

    Z. Sharif (Zara)

    2016-01-01

    markdownabstractThree essays on strategic communication are discussed in this dissertation. These essays consider different settings in which a decision maker has to rely on another agent for information. In each essay, we analyze how much information the sender is able to credibly communicate to

  9. Mother-child communication

    DEFF Research Database (Denmark)

    Demuth, Carolin

    2015-01-01

    Communication with children plays a crucial role not only for cognitive and social-emotional development but also in a more general sense for an understanding of self and self in relation to others. Research from linguistic anthropology and cultural developmental psychology have shown...... that there exists a great variety of cultural genres of communicating with children that are in line with the relevant broader cultural ideologies of good child care. Culture, communication, and self- development are inextricably intertwined. Culturally distinct communicative practices in which children participate...... will therefore ultimately lead to different cultural developmental pathways. While traditional research in developmental psychology has focused on mother–child dyads and experimental designs there is an increasing recognition of the need for naturalistic studies of everyday communication with children including...

  10. Organizational Communication and Media

    DEFF Research Database (Denmark)

    Tække, Jesper

      The paper reflects an interest in the relation between organizational communication and media. It tries to answer the question, how we can observe the relationship between organizational communication and media. It is a work-in-progress which tries to combine organizational studies inspired...... of Niklas Luhmann (Tække & Paulsen 2008, Tække 2008a) with analysis of how organizations communicate in and about media. Using systems theory and form theory, it puts forward a theoretical framework and a strategy for analysing organisational communication in and about media. The medium aspect is inspired...... is a possible framework to draw the two disciplines together in, because it is a theory about the relation between the social and the media it is based on. First the paper sum up the Luhmann inspired theory about organizations, fleshing out how organizations are thought to communicate in and about media and how...

  11. Scholarly communication changing

    DEFF Research Database (Denmark)

    Faber Frandsen, Tove

    2009-01-01

    Abstract The dissertation aims at investigating the changing scholarly communication in general and more specifically the implications of open access on scholarly communication. The overall research question is: What are the effects of open access on scholarly communication? The dissertation...... consists of five empirical studies of various aspects of the implications of open access on scholarly communication. The five studies, published as journal articles, are bibliometric studies conducted on three different levels. The first level consists of two studies of a general, more explorative....... Furthermore, the dissertation includes a chapter that presents and discusses the research findings in a theoretical framework. Initially the chapter presents and discusses terminology needed for analysing open access and scholarly communication. Following the necessary definitions and clarifications...

  12. Communication, ethics and anthropoethics

    Directory of Open Access Journals (Sweden)

    Luiz Martins da Silva

    2009-12-01

    Full Text Available The purpose of this article is to dream of – in the sense of establishing – the utopian perspective of a scenario that remains utopian but which nonetheless provides the first indications that we may be entering a new paradigm, that of communication-ethics, that is to say, the ethical dimension of communication, which in this case is not restricted to technological advancements but concerns communication with ethics and as ethics, to conclude that without ethics, there is no communication and by extension, no genuine mankind nor genuine humanity. Communication and ethics therefore appear inseparable; one cannot exist without the other. The audacity of this ethical visionary lies in managing to perceive more than just technological marvels, but also to appreciate the paradigm of anthropoethics entering the realm of the concrete, that is to say, ethics for mankind and for humanity, as conceived of by Apel, Habermas and Morin.

  13. Heidegger, communication, and healthcare.

    Science.gov (United States)

    Rentmeester, Casey

    2018-01-12

    Communication between medical professionals and patients is an important aspect of therapy and patient satisfaction. Common barriers that get in the way of effective communication in this sphere include: (1) gender, age, and cultural differences; (2) physical or psychological discomfort or pain; (3) medical literacy; and (4) distraction due to technological factors or simply being overworked. The author examines these communicative barriers from a philosophical lens and then utilizes Martin Heidegger's phenomenology and hermeneutics to provide guidance for medical professional-patient interactions. The phenomenological approach espoused emphasizes the particular, contextual nature of such interactions, and thus is opposed to abstract, theoretical principles. Heidegger's hermeneutics provides a philosophical approach to communication that may guide the back-and-forth interpretation that should happen between medical professionals and patients to achieve effective communication.

  14. Interdiscursive leadership communication

    DEFF Research Database (Denmark)

    Frimann, Søren; Broeng, Susanne

    2014-01-01

    Communication realized as discourses, positions, and stories are the stuff leadership primarily is made of and recreated by. Leadership and organizational communication in late capitalism and postmodernity are characterized by hybridity, interdicursivity, and subtle discursive forms of power. We...... Communication (AMOC). We draw on developments in theories of leadership, power, and paradigms within the field of organizational communication. These developments are related to their social and historical contexts. We claim that awareness of approaches, paradigms, forms of power, and positions, as well...... as their historical background, form an important background of knowledge. Such knowledge gives the possibility to learn, meta-reflect, and react and relate in different ways to leadership, communication, power, and the interpersonal relations in organizations. It also gives the possibility to change position...

  15. Strategic Communication Institutionalized

    DEFF Research Database (Denmark)

    Kjeldsen, Anna Karina

    2013-01-01

    of institutionalization when strategic communication is not yet visible as organizational practice, and how can such detections provide explanation for the later outcome of the process? (2) How can studies of strategic communication benefit from an institutional perspective? How can the virus metaphor generate a deeper...... understanding of the mechanisms that interact from the time an organization is exposed to a new organizational idea such as strategic communication until it surfaces in the form of symptoms such as mission and vision statements, communication manuals and communication positions? The first part of the article...... focuses on a discussion of the virus metaphor as an alternative to the widespread fashion metaphor for processes of institutionalization. The second part of the article provides empirical examples of the virus metaphor employed, examples that are drawn from a study of the institutionalization of strategic...

  16. Communication in Adult Education

    Directory of Open Access Journals (Sweden)

    Mihaela Časar

    1997-12-01

    Full Text Available In their paper the authors point to the importance of communication in adult education, seeing man as a relational creature. They stress the importance verbal as well as non-verbal communication, which discloses the speaker's attitude to both what is being said and the students. The authors detail the components of non-verbal communication, which the group leaders can use as guide­ lines in their educational work. They define constructive and destructive, content-related and relationship-related types of communication, concluding that communication is at its best when it is relaxed and involves all members of the group as well as the tutor-organiser. Only then can feedback be generated, resulting in a closer connectedness and enhanced quality of the process of education.

  17. INTERCULTURAL COMMUNICATION IN TOURISM

    Directory of Open Access Journals (Sweden)

    Cristina Elena ALBU

    2015-06-01

    Full Text Available Communication is involved in all social life acts, being the constituent factor of creation and of cultural processes. Cultural diversity and intercultural dialogue are intensely discussed topics in today's society which is marked by globalization. Cultural differences are the core subject for studies addressing intercultural communication. Good knowledge of other cultures is a necessary step to get to recognize the nature of these differences and to relate to others through attitudes of understanding and tolerance which are premises for genuine intercultural dialogue, especially in the tourism industry. While communication is an act of human relationships, culture is the motive of this act. In tourism, quality of communication is related to the level of the culture involved and to the degree of improvement of the means of which is done. Intercultural communication experiences help tourists to know and to appreciate other cultures, but also help them to a better understanding of their own culture.

  18. COMMUNICATION, ETHICS AND ANTHROPOETHICS

    Directory of Open Access Journals (Sweden)

    Luiz Martins da Silva

    2009-12-01

    Full Text Available The purpose of this article is to dream of – in the sense ofestablishing – the utopian perspective of a scenario that remains utopian but which nonetheless provides the first indications that we may be entering a new paradigm, that of communication-ethics, that is to say, the ethical dimension of communication, which in this case is not restricted to technological advancements but concerns communication with ethics and as ethics, to conclude that without ethics, there is no communication and by extension, no genuine mankind nor genuine humanity. Communication and ethics therefore appear inseparable; one cannot exist without the other. The audacity of this ethical visionary lies in managing to perceive more than just technological marvels, but also to appreciate the paradigm of anthropoethics entering the realm of the concrete, that is to say, ethics for mankind and for humanity, as conceived of by Apel, Habermas and Morin.

  19. MARCKS-related protein regulates cytoskeletal organization at cell-cell and cell-substrate contacts in epithelial cells.

    Science.gov (United States)

    Van Itallie, Christina M; Tietgens, Amber Jean; Aponte, Angel; Gucek, Marjan; Cartagena-Rivera, Alexander X; Chadwick, Richard S; Anderson, James M

    2018-02-02

    Treatment of epithelial cells with interferon-γ and TNF-α (IFN/TNF) results in increased paracellular permeability. To identify relevant proteins mediating barrier disruption, we performed proximity-dependent biotinylation (BioID) of occludin and found that tagging of MARCKS-related protein (MRP; also known as MARCKSL1) increased ∼20-fold following IFN/TNF administration. GFP-MRP was focused at the lateral cell membrane and its overexpression potentiated the physiological response of the tight junction barrier to cytokines. However, deletion of MRP did not abrogate the cytokine responses, suggesting that MRP is not required in the occludin-dependent IFN/TNF response. Instead, our results reveal a key role for MRP in epithelial cells in control of multiple actin-based structures, likely by regulation of integrin signaling. Changes in focal adhesion organization and basal actin stress fibers in MRP-knockout (KO) cells were reminiscent of those seen in FAK-KO cells. In addition, we found alterations in cell-cell interactions in MRP-KO cells associated with increased junctional tension, suggesting that MRP may play a role in focal adhesion-adherens junction cross talk. Together, our results are consistent with a key role for MRP in cytoskeletal organization of cell contacts in epithelial cells. © 2018. Published by The Company of Biologists Ltd.

  20. Single-cell protein secretomic signatures as potential correlates to tumor cell lineage evolution and cell-cell interaction

    Directory of Open Access Journals (Sweden)

    Minsuk eKwak

    2013-02-01

    Full Text Available Secreted proteins including cytokines, chemokines and growth factors represent important functional regulators mediating a range of cellular behavior and cell-cell paracrine/autocrine signaling, e.g. in the immunological system, tumor microenvironment or stem cell niche. Detection of these proteins is of great value not only in basic cell biology but also for diagnosis and therapeutic monitoring of human diseases such as cancer. However, due to co-production of multiple effector proteins from a single cell, referred to as polyfunctionality, it is biologically informative to measure a panel of secreted proteins, or secretomic signature, at the level of single cells. Recent evidence further indicates that a genetically-identical cell population can give rise to diverse phenotypic differences. It is known that cytokines, for example, in the immune system define the effector functions and lineage differentiation of immune cells. In this Perspective Article, we hypothesize that protein secretion profile may represent a universal measure to identify the definitive correlate in the larger context of cellular functions to dissect cellular heterogeneity and evolutionary lineage relationship in human cancer.

  1. Loss of E-Cadherin-Dependent Cell-Cell Adhesion and the Development and Progression of Cancer.

    Science.gov (United States)

    Bruner, Heather C; Derksen, Patrick W B

    2018-03-01

    Classical cadherins are the key molecules that control cell-cell adhesion. Notwithstanding this function, it is also clear that classical cadherins are more than just the "glue" that keeps the cells together. Cadherins are essential regulators of tissue homeostasis that govern multiple facets of cellular function and development, by transducing adhesive signals to a complex network of signaling effectors and transcriptional programs. In cancer, cadherins are often inactivated or functionally inhibited, resulting in disease development and/or progression. This review focuses on E-cadherin and its causal role in the development and progression of breast and gastric cancer. We provide a summary of the biochemical consequences and consider the conceptual impact of early (mutational) E-cadherin loss in cancer. We advocate that carcinomas driven by E-cadherin loss should be considered "actin-diseases," caused by the specific disruption of the E-cadherin-actin connection and a subsequent dependence on sustained actomyosin contraction for tumor progression. Based on the available data from mouse and human studies we discuss opportunities for targeted clinical intervention. Copyright © 2018 Cold Spring Harbor Laboratory Press; all rights reserved.

  2. CRIM1 complexes with ß-catenin and cadherins, stabilizes cell-cell junctions and is critical for neural morphogenesis.

    Directory of Open Access Journals (Sweden)

    Virgilio G Ponferrada

    Full Text Available In multicellular organisms, morphogenesis is a highly coordinated process that requires dynamically regulated adhesion between cells. An excellent example of cellular morphogenesis is the formation of the neural tube from the flattened epithelium of the neural plate. Cysteine-rich motor neuron protein 1 (CRIM1 is a single-pass (type 1 transmembrane protein that is expressed in neural structures beginning at the neural plate stage. In the frog Xenopus laevis, loss of function studies using CRIM1 antisense morpholino oligonucleotides resulted in a failure of neural development. The CRIM1 knockdown phenotype was, in some cases, mild and resulted in perturbed neural fold morphogenesis. In severely affected embryos there was a dramatic failure of cell adhesion in the neural plate and complete absence of neural structures subsequently. Investigation of the mechanism of CRIM1 function revealed that it can form complexes with ß-catenin and cadherins, albeit indirectly, via the cytosolic domain. Consistent with this, CRIM1 knockdown resulted in diminished levels of cadherins and ß-catenin in junctional complexes in the neural plate. We conclude that CRIM1 is critical for cell-cell adhesion during neural development because it is required for the function of cadherin-dependent junctions.

  3. Pseudomonas aeruginosa Transmigrates at Epithelial Cell-Cell Junctions, Exploiting Sites of Cell Division and Senescent Cell Extrusion.

    Directory of Open Access Journals (Sweden)

    Guillaume Golovkine

    2016-01-01

    Full Text Available To achieve systemic infection, bacterial pathogens must overcome the critical and challenging step of transmigration across epithelial barriers. This is particularly true for opportunistic pathogens such as Pseudomonas aeruginosa, an agent which causes nosocomial infections. Despite extensive study, details on the mechanisms used by this bacterium to transmigrate across epithelial tissues, as well as the entry sites it uses, remain speculative. Here, using real-time microscopy and a model epithelial barrier, we show that P. aeruginosa employs a paracellular transmigration route, taking advantage of altered cell-cell junctions at sites of cell division or when senescent cells are expelled from the cell layer. Once a bacterium transmigrates, it is followed by a cohort of bacteria using the same entry point. The basal compartment is then invaded radially from the initial penetration site. Effective transmigration and propagation require type 4 pili, the type 3 secretion system (T3SS and a flagellum, although flagellum-deficient bacteria can occasionally invade the basal compartment from wounded areas. In the basal compartment, the bacteria inject the T3SS toxins into host cells, disrupting the cytoskeleton and focal contacts to allow their progression under the cells. Thus, P. aeruginosa exploits intrinsic host cell processes to breach the epithelium and invade the subcellular compartment.

  4. The phylogenetic analysis of tetraspanins projects the evolution of cell-cell interactions from unicellular to multicellular organisms.

    Science.gov (United States)

    Huang, Shengfeng; Yuan, Shaochun; Dong, Meiling; Su, Jing; Yu, Cuiling; Shen, Yang; Xie, Xiaojin; Yu, Yanhong; Yu, Xuesong; Chen, Shangwu; Zhang, Shicui; Pontarotti, Pierre; Xu, Anlong

    2005-12-01

    In animals, the tetraspanins are a large superfamily of membrane proteins that play important roles in organizing various cell-cell and matrix-cell interactions and signal pathways based on such interactions. However, their origin and evolution largely remain elusive and most of the family's members are functionally unknown or less known due to difficulties of study, such as functional redundancy. In this study, we rebuilt the family's phylogeny with sequences retrieved from online databases and our cDNA library of amphioxus. We reveal that, in addition to in metazoans, various tetraspanins are extensively expressed in protozoan amoebae, fungi, and plants. We also discuss the structural evolution of tetraspanin's major extracellular domain and the relation between tetraspanin's duplication and functional redundancy. Finally, we elucidate the coevolution of tetraspanins and eukaryotes and suggest that tetraspanins play important roles in the unicell-to-multicell transition. In short, the study of tetraspanin in a phylogenetic context helps us understand the evolution of intercellular interactions.

  5. Communication system for emergency

    International Nuclear Information System (INIS)

    Ajioka, Yoshiteru

    1996-01-01

    People are apprehensive that a strong earthquake with a magnitude of nearly 8 may occur in Tokai area. The whole area of Shizuoka Prefecture has been specified as the specially strengthened region for earthquake disaster measures. This report outlines the communication system for emergency with respect to atomic disaster caused by an earthquake. Previously, wireless receiving system is stationed in the whole area to simultaneously inform the related news to the residents and so, communications with them are possible at any time by using the system. Since mobile wireless receiving sets are stationed in all town halls, self defense organizations and all the places of refuge, mutual communications are possible. These communication system can be utilized for either earthquake or nuclear disaster. Further, Shizuoka general information network system has been established as a communication system for anti-disaster organization and a wireless network via a communication satellite, ''super bird'' has been constructed in addition to the ground network. Therefore, the two communication routes became usable at emergency and the systems are available in either of nuclear disaster or earthquake. (M.N.)

  6. NASA science communications strategy

    Science.gov (United States)

    1995-01-01

    In 1994, the Clinton Administration issued a report, 'Science in the National Interest', which identified new national science goals. Two of the five goals are related to science communications: produce the finest scientists and engineers for the 21st century, and raise scientific and technological literacy of all Americans. In addition to the guidance and goals set forth by the Administration, NASA has been mandated by Congress under the 1958 Space Act to 'provide for the widest practicable and appropriate dissemination concerning its activities and the results thereof'. In addition to addressing eight Goals and Plans which resulted from a January 1994 meeting between NASA and members of the broader scientific, education, and communications community on the Public Communication of NASA's Science, the Science Communications Working Group (SCWG) took a comprehensive look at the way the Agency communicates its science to ensure that any changes the Agency made were long-term improvements. The SCWG developed a Science Communications Strategy for NASA and a plan to implement the Strategy. This report outlines a strategy from which effective science communications programs can be developed and implemented across the agency. Guiding principles and strategic themes for the strategy are provided, with numerous recommendations for improvement discussed within the respective themes of leadership, coordination, integration, participation, leveraging, and evaluation.

  7. JINR rapid communications. Collection no. 5

    International Nuclear Information System (INIS)

    1992-01-01

    The volume includes 7 communications in the field of elementary particle physics (3 communications), nuclear physics (1 communication), atoms and molecules (1 communication), accelerators (1 communication) and nuclear instrumentation (1 communication). A separate abstract was prepared for each of them

  8. Science Communication in Denmark

    DEFF Research Database (Denmark)

    Busch, Henrik

    2005-01-01

    This paper was presented during the author?s visit at the Faculty of Human Development of the University of Kobe . The paper is intended to provide the knowledge about science communication in the Nordic countries (in particular in Denmark). The focus in the paper is on (i) examples of new...... and innovative modes of science communication in Denmark and (ii) educational programs for science communicators. Furthermore, emphasis is on the pedagogical ideas behind the initiatives, rather than on thorough descriptions of structures, curricula and evaluations of the projects....

  9. Communications technology handbook

    CERN Document Server

    Lewis, Geoff

    2013-01-01

    This is the first point of reference for the communications industries. It offers an introduction to a wide range of topics and concepts encountered in the field of communications technology. Whether you are looking for a simple explanation, or need to go into a subject in more depth, the Communications Technology Handbook provides all the information you need in one single volume.This second edition has been updated to include the latest technology including: Video on DemandWire-less Distribution systemsHigh spee

  10. Customer Communication Document

    Science.gov (United States)

    2009-01-01

    This procedure communicates to the Customers of the Automation, Robotics and Simulation Division (AR&SD) Dynamics Systems Test Branch (DSTB) how to obtain services of the Six-Degrees-Of-Freedom Dynamic Test System (SDTS). The scope includes the major communication documents between the SDTS and its Customer. It established the initial communication and contact points as well as provides the initial documentation in electronic media for the customer. Contact the SDTS Manager (SM) for the names of numbers of the current contact points.

  11. Serial interprocessor communications system

    International Nuclear Information System (INIS)

    Labiak, W.; Siemens, P.; Bailey, C.

    1980-01-01

    A serial communications system based on the EIA RS232-C standard with modem control lines has been developed. The DLV11-E interface is used for this purpose. All handshaking is done with the modem control lines. This allows totally independent full duplex communication. The message format consists of eight bit data with odd parity and a sixteen bit checksum on the whole message. All communications are fully interrupt driven. A program was written to load a program into a remote LSI-11 using the serial line without bootstrap ROM

  12. COMMUNICATING FOR SUCCESS

    Directory of Open Access Journals (Sweden)

    Brindusa Maria Popa

    2016-10-01

    Full Text Available Organizational communication, both internal and external, affects organizational efficiency and effectiveness and consequently, the objectives of the organization. Communication is one the elements of the organizational life which is taken for granted and most of the times overlooked. It is pervasive and inherent in all activities thus, it cannot be analyzed in isolation, but in an organizational context. A well structured communication system will impact the performance of the organization through the quantity, but mostly the quality of the information it transports. Information should be clear, concise, specific, open, multi-directional.

  13. Digital communication system

    Science.gov (United States)

    Monford, L. G., Jr. (Inventor)

    1974-01-01

    A digital communication system is reported for parallel operation of 16 or more transceiver units with the use of only four interconnecting wires. A remote synchronization circuit produces unit address control words sequentially in data frames of 16 words. Means are provided in each transceiver unit to decode calling signals and to transmit calling and data signals. The transceivers communicate with each other over one data line. The synchronization unit communicates the address control information to the transceiver units over an address line and further provides the timing information over a clock line. A reference voltage level or ground line completes the interconnecting four wire hookup.

  14. 75 FR 5241 - Maritime Communications

    Science.gov (United States)

    2010-02-02

    ...] Maritime Communications AGENCY: Federal Communications Commission. ACTION: Final rule. SUMMARY: In this... that its rules governing the Maritime Radio Services continue to promote maritime safety, maximize effective and efficient use of the spectrum available for maritime communications, accommodate technological...

  15. Visual implementation of computer communication

    OpenAIRE

    Gunnarsson, Tobias; Johansson, Hans

    2010-01-01

    Communication is a fundamental part of life and during the 20th century several new ways for communication has been developed and created. From the first telegraph which made it possible to send messages over long distances to radio communication and the telephone. In the last decades, computer to computer communication at high speed has become increasingly important, and so also the need for understanding computer communication. Since data communication today works in speeds that are so high...

  16. Machine Translation Effect on Communication

    DEFF Research Database (Denmark)

    Jensen, Mika Yasuoka; Bjørn, Pernille

    2011-01-01

    Intercultural collaboration facilitated by machine translation has gradually spread in various settings. Still, little is known as for the practice of machine-translation mediated communication. This paper investigates how machine translation affects intercultural communication in practice. Based...... on communication in which multilingual communication system is applied, we identify four communication types and its’ influences on stakeholders’ communication process, especially focusing on establishment and maintenance of common ground. Different from our expectation that quality of machine translation results...

  17. Informationization nuclear apparatus communication technique

    International Nuclear Information System (INIS)

    Yu Tiqi; Fang Zongliang; Wen Qilin

    2006-01-01

    The paper explains the request of communication ability in nuclear technique application area. Based on the actuality of nuclear apparatus communication ability, and mainly combining with the development of communication technique, the authors analyzes the application trend of communication technique applying in nuclear apparatus, for the apparatus and system needing communication ability, they need selecting suitable communication means to make them accomplish the task immediately and effectively. (authors)

  18. Karl Marx & Communication @ 200: Towards a Marxian Theory of Communication

    Directory of Open Access Journals (Sweden)

    Christian Fuchs

    2018-05-01

    Full Text Available This contribution takes Marx’s bicentenary as occasion for reflecting on foundations of a Marxian theory of communication. It aims to show that Marx provides a consistent account as foundation for a critical, dialectical theory of communication. The article first discusses the relationship of communication and materialism in order to ground a communicative materialism that avoids the dualist assumption that communication is a superstructure erected on a material base. Second, the paper provides an overview of how Marx’s approach helps us to understand the role of the means of communication and communicative labour in capitalism. Third, it conceives of ideology as a form of fetishised communication and fetishism as ideological communication. Given that communicative capitalism is a significant dimension of contemporary society, it is about time to develop a Marxian theory of communication.

  19. Organizational Communication: Communication and Motivation in The Workplace

    Directory of Open Access Journals (Sweden)

    Sari Ramadanty

    2016-01-01

    Full Text Available Every human activity was basically driven by the motivation. Work motivation was a condition or an energy that directed employees to achieve organizational goals of the company. Nowadays, the development of organizational communication saw the communication as one of the most dominant and important activity in the organization and it could be able to motivate employees. The purpose of this study was to reveal how the role of the communication that occurs within the organization could give the motivation to employee. The problem of the research was the relationship employee motivation with factors of communication, such as nonverbal communication, interpersonal communication leadership and communication climate. The method used descriptive qualitative method. Methods of data collection of this study were literature study. Research finds that nonverbal communication, interpersonal communication leadership and communication climate have a significant role to form employee motivation. Nonverbal communication has slightly strong role in shaping the positive motivation to employee. The role includes body communication, facial communication and eye communication. Interpersonal communication leader is based on the satisfaction level of information between management and employees. Management and transparency in openness in downward communication under the form of information from superiors are by listening the communication between supervisors and employees are running smoothly. 

  20. Identifying Error in AUV Communication

    National Research Council Canada - National Science Library

    Coleman, Joseph; Merrill, Kaylani; O'Rourke, Michael; Rajala, Andrew G; Edwards, Dean B

    2006-01-01

    Mine Countermeasures (MCM) involving Autonomous Underwater Vehicles (AUVs) are especially susceptible to error, given the constraints on underwater acoustic communication and the inconstancy of the underwater communication channel...

  1. Communicating science: professional, popular, literary

    National Research Council Canada - National Science Library

    Russell, Nicholas J

    2010-01-01

    .... This book critically examines the origin of this drive to improve communication, and discusses why simply improving scientists' communication skills and understanding of their audiences may not be...

  2. Communication satellite applications

    Science.gov (United States)

    Pelton, Joseph N.

    The status and future of the technologies, numbers and services provided by communications satellites worldwide are explored. The evolution of Intelsat satellites and the associated earth terminals toward high-rate all-digital telephony, data, facsimile, videophone, videoconferencing and DBS capabilities are described. The capabilities, services and usage of the Intersputnik, Eutelsat, Arabsat and Palapa systems are also outlined. Domestic satellite communications by means of the Molniya, ANIK, Olympus, Intelsat and Palapa spacecraft are outlined, noting the fast growth of the market and the growing number of different satellite manufacturers. The technical, economic and service definition issues surrounding DBS systems are discussed, along with presently operating and planned maritime and aeronautical communications and positioning systems. Features of search and rescue and tracking, data, and relay satellite systems are summarized, and services offered or which will be offered by every existing or planned communication satellite worldwide are tabulated.

  3. Introduction: Communicating Reproduction.

    Science.gov (United States)

    Hopwood, Nick; Jones, Peter Murray; Kassell, Lauren; Secord, Jim

    2015-01-01

    Communication should be central to histories of reproduction, because it has structured how people do and do not reproduce. Yet communication has been so pervasive, and so various, that it is often taken for granted and the historical specificities overlooked. Making communication a frame for histories of reproduction can draw a fragmented field together, including by putting the promotion of esoteric ideas on a par with other practical activities. Paying communication close attention can revitalize the history of reproduction over the long term by highlighting continuities as well as the complex connections between new technologies and new approaches. Themes such as the power of storytelling, the claiming and challenging of expertise, and relations between knowledge and ignorance, secrecy and propriety also invite further study.

  4. Communicating with Professionals

    Medline Plus

    Full Text Available ... follow-up with your medical team. You can help improve the care you receive at follow-up ... or your professionals) want. Simple communication skills can help you get what you need – over the phone, ...

  5. Political communication research

    DEFF Research Database (Denmark)

    Nielsen, Rasmus Kleis

    2014-01-01

    The rise of new media and the broader set of social changes they are part of present political communication research with new challenges and new opportunities at a time when many think the field is at an intellectual impasse (e.g., Bennett & Iyengar, 2008). In this article, I argue that parts...... of the field’s problems are rooted in the way in which political communication research has developed since the 1960s. In this period, the field has moved from being interdisciplinary and mixed-methods to being more homogenous and narrowly focused, based primarily on ideas developed in social psychology......, certain strands of political science, and the effects-tradition of mass communication research. This dominant paradigm has contributed much to our understanding of some aspects of political communication. But it is struggling to make sense of many others, including questions concerning people’s experience...

  6. Communicating with Professionals

    Medline Plus

    Full Text Available ... getting the facts. Usually, office visits and phone calls are shorter and more rushed than you (or your professionals) want. Simple communication skills can help you get what you need – ...

  7. Emotional crisis communication

    NARCIS (Netherlands)

    van der Meer, T.G.L.A.; Verhoeven, J.W.M.

    2014-01-01

    Organizational crises are usually highly emotional experiences for both organizations and stakeholders. Hence, crisis situations often result in emotionally charged communication between the two parties. Despite the attention of organizations and scholars to the emotions of stakeholders during

  8. Economic communication model set

    Science.gov (United States)

    Zvereva, Olga M.; Berg, Dmitry B.

    2017-06-01

    This paper details findings from the research work targeted at economic communications investigation with agent-based models usage. The agent-based model set was engineered to simulate economic communications. Money in the form of internal and external currencies was introduced into the models to support exchanges in communications. Every model, being based on the general concept, has its own peculiarities in algorithm and input data set since it was engineered to solve the specific problem. Several and different origin data sets were used in experiments: theoretic sets were estimated on the basis of static Leontief's equilibrium equation and the real set was constructed on the basis of statistical data. While simulation experiments, communication process was observed in dynamics, and system macroparameters were estimated. This research approved that combination of an agent-based and mathematical model can cause a synergetic effect.

  9. Communicating with Professionals

    Medline Plus

    Full Text Available ... concerns, asking questions and getting the facts. Usually, office visits and phone calls are shorter and more ... over the phone, at the hospital or during office visits. Good communication skills help you get better ...

  10. Psychology of communications

    International Nuclear Information System (INIS)

    Hunns, D.M.

    1980-01-01

    A theory is proposed relating to the structuring of mental models and this theory used to account for a number of human error mechanisms. Communications amongst operators and the systems around them is seen as a vital factor in the area of human error and a technique, communications analysis, is proposed as one approach to systematically predicting the ways in which actual system state and the operators' perceptions of that state can get out of step and lead to catastrophe. To be most effective it is expected that the analyst would apply communications analyst with an interactive computer system. Of particular importance is the ability to trace the operator-system communication scenarios in various abnormal system configurations. (orig.)

  11. Laser Communications Relay Demonstration

    Data.gov (United States)

    National Aeronautics and Space Administration — LCRD is a minimum two year flight demonstration in geosynchronous Earth orbit to advance optical communications technology toward infusion into Deep Space and Near...

  12. Research and Communication Officer

    International Development Research Centre (IDRC) Digital Library (Canada)

    guidance on problems relating to the Centre's programming and issues of ... Ability to use information and communication technologies and virtual media navigation ... Tact and maturity for successful interpersonal and professional contacts.

  13. Communicating with Professionals

    Medline Plus

    Full Text Available ... to follow-up with your medical team. You can help improve the care you receive at follow- ... you (or your professionals) want. Simple communication skills can help you get what you need – over the ...

  14. Communicating with Professionals

    Medline Plus

    Full Text Available ... summarizes communication tips This content was last reviewed March 2018. Video: Recovering From Your Surgery Find helpful ... Sodium and Salt 3 Heart Attack Symptoms in Women 4 Warning Signs of a Heart Attack 5 ...

  15. Improving Family Communications

    Science.gov (United States)

    ... Spread the Word Shop AAP Find a Pediatrician Family Life Medical Home Family Dynamics Adoption & Foster Care ... Listen Español Text Size Email Print Share Improving Family Communications Page Content Article Body How can I ...

  16. Credentialed Secure Communication "Switchboards"

    National Research Council Canada - National Science Library

    Freudenthal, Eric; Port, Lawrence; Keenan, Edward; Pesin, Tracy; Karamcheti, Vijay

    2001-01-01

    ... with connection monitoring facilities. Switchboard extends the secure authenticated communication channel abstraction provided by standard interfaces such as SSL/TLS with mechanisms to support trust management, key sharing, service...

  17. Communicating with Professionals

    Medline Plus

    Full Text Available ... communication skills can help you get what you need – over the phone, at the hospital or during ... complies with the HONcode standard for trustworthy health information: verify here.

  18. Domestic Communication Satellites

    Science.gov (United States)

    Horowitz, Andrew

    1974-01-01

    A discussion of the Federal Communications Commission's new policy on domestic satellites in light of our 1) military and economic history; 2) corporate interests; 3) citizen surveillance; and 4) media control. (HB)

  19. The Corporate Communication Manager.

    Science.gov (United States)

    Harris, Thomas E.; Bryant, Jennings

    1986-01-01

    Reports the results of a survey of Fortune 500 companies regarding the position of communications manager. Profiles the responsibilities, typical salary, and usefulness of the position as perceived by respondents. (MS)

  20. Political communication in referendums

    NARCIS (Netherlands)

    de Vreese, C.H.; Schuck, A.R.T.; Reinemann, C.

    2014-01-01

    This chapter reviews research on political communication in referendums that have become increasingly popular in democracies worldwide. The authors define key characteristics of referendums, touch upon participation in and popular support for referendums, and highlight the differences between them

  1. White House Communications Agency

    National Research Council Canada - National Science Library

    Gimble, Thomas

    1995-01-01

    ...; and the Deputy Secretary of Defense requested the audit. The Deputy Secretary of Defense emphasized that this review should be as thorough as possible of all White House Communications Agency (WHCA...

  2. Comparing Political Communication

    OpenAIRE

    Pfetsch, Barbara; Esser, Frank

    2012-01-01

    This chapter describes the maturation of comparative political communications as a sub-discipline and defines its conceptual core. It then lays out the concept of “political communication system”. At the macro-level, this model captures the patterns of interaction between media and politics as social systems; at the micro-level it captures the interactions between media and political actors as individuals or organizations. Comparative research in this tradition focuses on the structure of pol...

  3. Management in Professional Communication

    OpenAIRE

    Irama Milei Flores

    2012-01-01

    The following work describes to the type of existing communication in the professional schools and the strategies that use this type of organizations, to interact with its public. This reality is compared, with the theoretical expositions that in the matter of organizational communication, contribute students like: The Fernandez (1997), Goldhaber (1984), Serna (1996), Bartoli (1992), Go Rail (1998), among others. The study was developed in a sample of 104 affiliated and 4 Secretary Generals o...

  4. Programmable synchronous communications module

    International Nuclear Information System (INIS)

    Horelick, D.

    1979-10-01

    The functional characteristics of a programmable, synchronous serial communications CAMAC module with buffering in block format are described. Both bit and byte oriented protocols can be handled in full duplex depending on the program implemented. The main elements of the module are a Signetics 2652 Multi-Protocol Communications Controller, a Zilog Z-808 8 bit microprocessor with PROM and RAM, and FIFOs for buffering

  5. Risk communication basics

    International Nuclear Information System (INIS)

    Corrado, P.G.

    1995-01-01

    In low-trust, high-concern situations, 50% of your credibility comes from perceived empathy and caring, demonstrated in the first 30 s you come in contact with someone. There is no second chance for a first impression. These and other principles contained in this paper provide you with a basic level of understanding of risk communication. The principles identified are time-tested caveats and will assist you in effectively communicating technical information

  6. Industrial communication technology handbook

    CERN Document Server

    Zurawski, Richard

    2014-01-01

    Featuring contributions from major technology vendors, industry consortia, and government and private research establishments, the Industrial Communication Technology Handbook, Second Edition provides comprehensive and authoritative coverage of wire- and wireless-based specialized communication networks used in plant and factory automation, automotive applications, avionics, building automation, energy and power systems, train applications, and more.New to the Second Edition:46 brand-new chapters and 21 substantially revised chaptersInclusion of the latest, most significant developments in spe

  7. Advanced digital optical communications

    CERN Document Server

    Binh, Le Nguyen

    2015-01-01

    This book provides a fundamental understanding of digital communication applications in optical communication technologies. Emphasizing operation principles versus mathematical analysis, the Second Edition includes new coverage of superchannel optical transmission systems, metropolitan and long-haul optical systems and networks, and Nyquist pulse shaping and high spectral efficiency of optical transmission systems, as well as new homework problems and examples. Featuring theoretical foundations as well as practical case studies, the text focuses on enhancements to digital technologies that are

  8. The SKI communication programme

    International Nuclear Information System (INIS)

    Carlberg, Susanne

    2000-01-01

    Sweden has, since many years, an ongoing debate on nuclear power in general and nuclear safety and nuclear waste in particular. SKI is not the only part who wants to communicate about these subjects. The nuclear power plants, other authorities, the anti-nuclear groups and the politicians are other parts on the communication scene. The role of SKI is to provide the Swedish public with objective and prompt information based on facts. (author)

  9. Risk communication basics

    Energy Technology Data Exchange (ETDEWEB)

    Corrado, P.G. [Lawrence Livermore National Laboratory, CA (United States)

    1995-12-31

    In low-trust, high-concern situations, 50% of your credibility comes from perceived empathy and caring, demonstrated in the first 30 s you come in contact with someone. There is no second chance for a first impression. These and other principles contained in this paper provide you with a basic level of understanding of risk communication. The principles identified are time-tested caveats and will assist you in effectively communicating technical information.

  10. Digital Communication and Modulation

    DEFF Research Database (Denmark)

    Sørensen, John Aasted

    2010-01-01

    Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Spring 2010 Extent: 7.5 ects Class size: 9......Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Spring 2010 Extent: 7.5 ects Class size: 9...

  11. Digital Communication and Modulation

    DEFF Research Database (Denmark)

    Sørensen, John Aasted

    2010-01-01

    Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Autumn 2010 Extent: 7.5 ects Class size: 18......Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Autumn 2010 Extent: 7.5 ects Class size: 18...

  12. Communication about risks

    International Nuclear Information System (INIS)

    1988-01-01

    The conditions, difficulties and possibilities of communication on technological risks are detailed here. There is a description of the types and levels of argument on risks and the risk-concept itself, of the research field of risk communication, of the conceptional frame-work of the working-party, of the research programme and of the chances for a long-term prospect from the group. (DG) [de

  13. Relativity of Visual Communication

    OpenAIRE

    Arto Mutanen

    2016-01-01

    Communication is sharing and conveying information. In visual communication especially visual messages have to be formulated and interpreted. The interpretation is relative to a method of information presentation method which is human construction. This holds also in the case of visual languages. The notions of syntax and semantics for visual languages are not so well founded as they are for natural languages. Visual languages are both syntactically and semantically dense. The density is conn...

  14. Multichannel Human Body Communication

    International Nuclear Information System (INIS)

    Przystup, Piotr; Bujnowski, Adam; Wtorek, Jerzy

    2016-01-01

    Human Body Communication is an attractive alternative for traditional wireless communication (Bluetooth, ZigBee) in case of Body Sensor Networks. Low power, high data rates and data security makes it ideal solution for medical applications. In this paper, signal attenuation for different frequencies, using FR4 electrodes, has been investigated. Performance of single and multichannel transmission with frequency modulation of analog signal has been tested. Experiment results show that HBC is a feasible solution for transmitting data between BSN nodes

  15. RELATIONSHIPS AND COMMUNICATION NETWORKS

    OpenAIRE

    Stefan VLADUTESCU

    2012-01-01

    The main feature of the present situation regarding communication is the impregnation of the social with technology. Computer-mediated communication systems has led to the crystallization of a strong specific interactions. This article describes how human relationships constitues the ontological pillar of society and social relations form the axis irradiance of sociology. Overall, as social agents in social space, people come in a variety of social relationships. Thus, a distinct note of the ...

  16. INTERPERSONAL COMMUNICATION: PSYCHOLINGUISTIC ASPECT

    Directory of Open Access Journals (Sweden)

    Mitrofanova, I.I.

    2016-09-01

    Full Text Available The article considers language as the organization of the speech of any person in any situation, without which it is impossible to characterize the internal structure of the speech stream. Language is exactly a system of guidelines necessary for the activity in the social world. Communication is primarily nothing but as a way of making one or another correction in the image of the interlocutor’s world. In order for a language to serve as a means of communication, it must have a single or a similar understanding of reality behind it. Conversely, the unity of understanding the reality and the unity of coherence presuppose the possibility of adequate communication. A mandatory component of communication is the communicative act, that is, the act of sharing information between people. The speech, i.e. the natural sound language is an important means of conveying information that defines this aspect of the communication process as verbal communication. The idea of dialogue as the space, in which the exchange of information takes place, is defined as initial. Essentially, it is the dialogue that in this case acts as the backbone principle in dealing with problems of language. It is here that the essence of social and psychological transition to the analysis of communication is most visibly concentrated. An individual essentially "lives" in the world of Another person’s worlds, and studying the words of this person, he or she studies the "world" of Another person. Thus, the dialogue is not merely the interaction (verbal with another person, but, ultimately, the interaction with the world of culture.

  17. MFC Communications Infrastructure Study

    Energy Technology Data Exchange (ETDEWEB)

    Michael Cannon; Terry Barney; Gary Cook; George Danklefsen, Jr.; Paul Fairbourn; Susan Gihring; Lisa Stearns

    2012-01-01

    Unprecedented growth of required telecommunications services and telecommunications applications change the way the INL does business today. High speed connectivity compiled with a high demand for telephony and network services requires a robust communications infrastructure.   The current state of the MFC communication infrastructure limits growth opportunities of current and future communication infrastructure services. This limitation is largely due to equipment capacity issues, aging cabling infrastructure (external/internal fiber and copper cable) and inadequate space for telecommunication equipment. While some communication infrastructure improvements have been implemented over time projects, it has been completed without a clear overall plan and technology standard.   This document identifies critical deficiencies with the current state of the communication infrastructure in operation at the MFC facilities and provides an analysis to identify needs and deficiencies to be addressed in order to achieve target architectural standards as defined in STD-170. The intent of STD-170 is to provide a robust, flexible, long-term solution to make communications capabilities align with the INL mission and fit the various programmatic growth and expansion needs.

  18. Solar effects on communications

    International Nuclear Information System (INIS)

    Cleveland, F.; Malcolm, W.; Nordell, D.E.; Zirker, J.

    1991-01-01

    When people involved in the power industry think of Solar Magnetic Disturbances (SMD), they normally consider the potential for disrupting power transmission which results form solar-induced disturbances to the earth's magnetic field known as geomagnetic storms. However, in addition to the disruption of power transmission, solar phenomena can interfere with utility communication systems. Utilities use many different types of communication media, some of which can be affected by various solar phenomena. These include wire-based facilities (metallic cables and power line carrier), radio systems (HF, VHF, UHF mobile radio, microwave networks, and satellite transmissions), and fiber optic systems. This paper reports that the solar flares and other solar phenomena can affect these media through different mechanisms: Radio communications can be disturbed by flare-induced changes in the ionispheric layer of the atmosphere; Cable communications can be disrupted by the flare-induced changes in the magnetosphere which surrounds the earth. These changes, in turn, induce currents in the power equipment that energizes long communications cables; Satellite communications can be disrupted by the flare-induced perturbations of satellite orbits and equipment

  19. [Communication among hospital leaders].

    Science.gov (United States)

    Haberey-Knuessi, Véronique; Heeb, Jean-Luc; De Morgan, Paula Emilie

    2013-12-01

    New management styles imposed on hospital institutions in recent years, have fundamentally changed the organization of the latter. Many texts discuss the consequences, specifically on the field of communication. The aim of this study was to understand the real impact of new management methods on communication by managers in hospital, but also on care teams in termes of satisfaction and/or stress. This two-year study was conducted among 900 executives in hospitals in Western Switzerland using a mixed methodology. A first phase of questionnaires highlighted the problematic areas, while a second phase in the form of organized group interviews in each hospital, had the objective of achieving a better understanding of the relationship between management and communication. The latter proved to be particularly significant in terms of results, and this is the one we focused on in this article.These results indeed show that a crucial role is given to communication by carers, and, at the same time a lessening of the time devoted to relationships, both among peers and with patients. Frustration then arises, which is not without consequences both for the management of patients and the institutions themselves. It is by means of these results that awareness is raised of the omnipresence of communication at all levels and the major advantages that positive dynamic supports. And, on the contrary, of the serious problems which may arise from management practice that do not give due importance to the dimension of communication, present in all sectors of the hospital.

  20. Chlorpromazine reduces the intercellular communication via gap junctions in mammalian cells

    International Nuclear Information System (INIS)

    Orellana, Juan A.; Palacios-Prado, Nicolas; Saez, Juan C.

    2006-01-01

    In the work presented herein, we evaluated the effect of chlorpromazine (CPZ) on gap junctions expressed by two mammalian cell types; Gn-11 cells (cell line derived from mouse LHRH neurons) and rat cortical astrocytes maintained in culture. We also attempted to elucidate possible mechanisms of action of CPZ effects on gap junctions. CPZ, in concentrations comparable with doses used to treat human diseases, was found to reduce the intercellular communication via gap junctions as evaluated with measurements of dye coupling (Lucifer yellow). In both cell types, maximal inhibition of functional gap junctions was reached within about 1 h of treatment with CPZ, an recovery was almost complete at about 5 h after CPZ wash out. In both cell types, CPZ treatment increased the phosphorylation state of connexin43 (Cx43), a gap junction protein subunit. Moreover, CPZ reduced the reactivity of Cx43 (immunofluorescence) at cell interfaces and concomitantly increased its reactivity in intracellular vesicles, suggesting an increased retrieval from and/or reduced insertion into the plasma membrane. CPZ also caused cellular retraction reducing cell-cell contacts in a reversible manner. The reduction in contact area might destabilize existing gap junctions and abrogate formation of new ones. Moreover, the CPZ-induced reduction in gap junctional communication may depend on the connexins (Cxs) forming the junctions. If Cx43 were the only connexin expressed, MAPK-dependent phosphorylation of this connexin would induce closure of gap junction channels

  1. Cell-cell interactions of isolated and cultured oligodendrocytes: formation of linear occluding junctions and expression of peculiar intramembrane particles.

    Science.gov (United States)

    Massa, P T; Szuchet, S; Mugnaini, E

    1984-12-01

    Oligodendrocytes were isolated from lamb brain. Freshly isolated cells and cultured cells, either 1- to 4-day-old unattached or 1- to 5-week-old attached, were examined by thin section and freeze-fracture electron microscopy. Freeze-fracture of freshly isolated oligodendrocytes showed globular and elongated intramembrane particles similar to those previously described in oligodendrocytes in situ. Enrichment of these particles was seen at sites of inter-oligodendrocyte contact. Numerous gap junctions and scattered linear tight junctional arrays were apparent. Gap junctions were connected to blebs of astrocytic plasma membrane sheared off during isolation, whereas tight junctions were facing extracellular space or blebs of oligodendrocytic plasma membrane. Thin sections of cultured, unattached oligodendrocytes showed rounded cell bodies touching one another at points without forming specialized cell junctions. Cells plated on polylysine-coated aclar dishes attached, emanated numerous, pleomorphic processes, and expressed galactocerebroside and myelin basic protein, characteristic markers for oligodendrocytes. Thin sections showed typical oligodendrocyte ultrastructure but also intermediate filaments not present in unattached cultures. Freeze-fracture showed intramembrane particles similar to but more numerous, and with a different fracture face repartition, than those seen in oligodendrocytes, freshly isolated or in situ. Gap junctions were small and rare. Apposed oligodendrocyte plasma membrane formed linear tight junctions which became more numerous with time in culture. Thus, cultured oligodendrocytes isolated from ovine brains develop and maintain features characteristic of mature oligodendrocytes in situ and can be used to explore formation and maintenance of tight junctions and possibly other classes of cell-cell interactions important in the process of myelination.

  2. Haemorrhagic snake venom metalloproteases and human ADAMs cleave LRP5/6, which disrupts cell-cell adhesions in vitro and induces haemorrhage in vivo.

    Science.gov (United States)

    Seo, Tadahiko; Sakon, Taketo; Nakazawa, Shiori; Nishioka, Asuka; Watanabe, Kohei; Matsumoto, Kaori; Akasaka, Mari; Shioi, Narumi; Sawada, Hitoshi; Araki, Satohiko

    2017-06-01

    Snake venom metalloproteases (SVMPs) are members of the a disintegrin and metalloprotease (ADAM) family of proteins, as they possess similar domains. SVMPs are known to elicit snake venom-induced haemorrhage; however, the target proteins and cleavage sites are not known. In this work, we identified a target protein of vascular apoptosis-inducing protein 1 (VAP1), an SVMP, relevant to its ability to induce haemorrhage. VAP1 disrupted cell-cell adhesions by relocating VE-cadherin and γ-catenin from the cell-cell junction to the cytosol, without inducing proteolysis of VE-cadherin. The Wnt receptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP5/6) are known to promote catenin relocation, and are rendered constitutively active in Wnt signalling by truncation. Thus, we examined whether VAP1 cleaves LRP5/6 to induce catenin relocation. Indeed, we found that VAP1 cleaved the extracellular region of LRP6 and LRP5. This cleavage removes four inhibitory β-propeller structures, resulting in activation of LRP5/6. Recombinant human ADAM8 and ADAM12 also cleaved LRP6 at the same site. An antibody against a peptide including the LRP6-cleavage site inhibited VAP1-induced VE-cadherin relocation and disruption of cell-cell adhesions in cultured cells, and blocked haemorrhage in mice in vivo. Intriguingly, animals resistant to the effects of haemorrhagic snake venom express variants of LRP5/6 that lack the VAP1-cleavage site, or low-density lipoprotein receptor domain class A domains involved in formation of the constitutively active form. The results validate LRP5/6 as physiological targets of ADAMs. Furthermore, they indicate that SVMP-induced cleavage of LRP5/6 causes disruption of cell-cell adhesion and haemorrhage, potentially opening new avenues for the treatment of snake bites. © 2017 Federation of European Biochemical Societies.

  3. Cancer patients' evaluation of communication

    DEFF Research Database (Denmark)

    Ross, Lone; Petersen, Morten Aagaard; Johnsen, Anna Thit

    2013-01-01

    The aims of this study were to assess how communication with health care staff is perceived by Danish cancer patients and to characterise those patients who report problems in communication.......The aims of this study were to assess how communication with health care staff is perceived by Danish cancer patients and to characterise those patients who report problems in communication....

  4. The Science of Strategic Communication

    Science.gov (United States)

    The field of Strategic Communication involves a focused effort to identify, develop, and present multiple types of communication media on a given subject. A Strategic Communication program recognizes the limitations of the most common communication models (primarily “one s...

  5. Communication Barriers in Distance Education

    Science.gov (United States)

    Isman, Aytekin; Dabaj, Fahme; Altinay, Fahriye; Altinay, Zehra

    2003-01-01

    Communication is a key concept as being the major tool for people in order to satisfy their needs. It is an activity which refers as process and effective communication requires qualified communication with the elimination of communication barriers. As it is known, distance education is a new trend by following contemporary facilities and tools…

  6. Communicating science: professional, popular, literary

    National Research Council Canada - National Science Library

    Russell, N

    2010-01-01

    ... patterns of communication among scientists, popular communication to the public and science in literature and drama. This three-part framework shows how historical and cultural factors operate in today's complex communication landscape, and should be actively considered when designing and evaluating science communication. Ideal for students and p...

  7. Quantum secure communication models comparison

    Directory of Open Access Journals (Sweden)

    Georgi Petrov Bebrov

    2017-12-01

    Full Text Available The paper concerns the quantum cryptography, more specifically, the quantum secure communication type of schemes. The main focus here is on making a comparison between the distinct secure quantum communication models – quantum secure direct communication and deterministic secure quantum communication, in terms of three parameters: resource efficiency, eavesdropping check efficiency, and security (degree of preserving the confidentiality.

  8. Social communication in bats.

    Science.gov (United States)

    Chaverri, Gloriana; Ancillotto, Leonardo; Russo, Danilo

    2018-05-15

    Bats represent one of the most diverse mammalian orders, not only in terms of species numbers, but also in their ecology and life histories. Many species are known to use ephemeral and/or unpredictable resources that require substantial investment to find and defend, and also engage in social interactions, thus requiring significant levels of social coordination. To accomplish these tasks, bats must be able to communicate; there is now substantial evidence that demonstrates the complexity of bat communication and the varied ways in which bats solve some of the problems associated with their unique life histories. However, while the study of communication in bats is rapidly growing, it still lags behind other taxa. Here we provide a comprehensive overview of communication in bats, from the reasons why they communicate to the diversity and application of different signal modalities. The most widespread form of communication is the transmission of a signaller's characteristics, such as species identity, sex, individual identity, group membership, social status and body condition, and because many species of bats can rely little on vision due to their nocturnal lifestyles, it is assumed that sound and olfaction are particularly important signalling modes. For example, research suggests that secretions from specialized glands, often in combination with urine and saliva, are responsible for species recognition in several species. These olfactory signals may also convey information about sex and colony membership. Olfaction may be used in combination with sound, particularly in species that emit constant frequency (CF) echolocation calls, to recognize conspecifics from heterospecifics, yet their simple structure and high frequency do not allow much information of individual identity to be conveyed over long distances. By contrast, social calls may encode a larger number of cues of individual identity, and their lower frequencies increase their range of detection. Social

  9. Satellite Communications for ATM

    Science.gov (United States)

    Shamma, Mohammed A.

    2003-01-01

    This presentation is an overview on Satellite Communication for the Aeronautical Telecommunication Management (ATM) research. Satellite Communications are being considered by the FAA and NASA as a possible alternative to the present and future ground systems supporting Air Traffic Communications. The international Civil Aviation Organization (ICAO) have in place Standards and Recommended Practices (SARPS) for the Aeronautical Mobile Satellite Services (AMSS) which is mainly derived from the pre-existing Inmarsat service that has been in service since the 1980s. The Working Group A of the Aeronautical Mobile Communication Panel of ICAO has also been investigating SARPS for what is called the Next Generation Satellite Service (NGSS) which conforms less to the Inmarsat based architecture and explores wider options in terms of satellite architectures. Several designs are being proposed by Firms such as Boeing, ESA, NASA that are geared toward full or secondary usage of satellite communications for ATM. Satellite communications for ATM can serve several purposes ranging from primary usage where ground services would play a minimal backup role, to an integrated solution where it will be used to cover services, or areas that are less likely to be supported by the proposed and existing ground infrastructure. Such Integrated roles can include usage of satellite communications for oceanic and remote land areas for example. It also can include relieving the capacity of the ground network by providing broadcast based services of Traffic Information Services messages (TIS-B), or Flight Information Services (FIS-B) which can take a significant portion of the ground system capacity. Additionally, satellite communication can play a backup role to support any needs for ground replacement, or additional needed capacity even after the new digital systems are in place. The additional bandwidth that can be provided via satellite communications can also open the door for many new

  10. Salutogenesis, globalization, and communication.

    Science.gov (United States)

    Petzold, Theodor Dierk; Lehmann, Nadja

    2011-12-01

    Achieving successful communication in transcultural contexts means integrating emotional communication patterns into a global context. Professional, rational communication is characteristic of the cultural dimension, and emotions are characteristic of the direct, interpersonal dimension of human existence. Humans strive to achieve coherence in all dimensions of their lives; this goal is in the end the most essential aspect of psychophysical self-regulation. A major role in integrating emotional needs and cultural features in global coherence is played by the attractor 'global affinity'. The transitions from emotional coherence to cultural coherence, and likewise from cultural coherence to global coherence, can cause considerable insecurity as well as psychological problems, which previously went by the name 'adjustment disorders'. However, instead of pathologizing these processes, we should understand them in a salutogenic sense as challenges important for both individual and collective development. The development of more coherence is regulated by the neuropsychological approach and avoidance system. This system can be consciously fostered by directing our attention to the commonalities of all human beings. Such a global salutogenic orientation furthers both communication and creativity in teamwork. This article introduces a consequent salutogenic and evolutionary systemic view of transcultural communication and demonstrates its effectiveness in a number of case examples.

  11. Management in Professional Communication

    Directory of Open Access Journals (Sweden)

    Irama Milei Flores

    2012-11-01

    Full Text Available The following work describes to the type of existing communication in the professional schools and the strategies that use this type of organizations, to interact with its public. This reality is compared, with the theoretical expositions that in the matter of organizational communication, contribute students like: The Fernandez (1997, Goldhaber (1984, Serna (1996, Bartoli (1992, Go Rail (1998, among others. The study was developed in a sample of 104 affiliated and 4 Secretary Generals of the schools of Lawyers, Engineers, Accountants Public and Journalists of the state Nueva Esparta (Venezuela and used like technique and tool to the survey and the questionnaire. Between the conclusions they tell, that the type of communication that predominates in the schools is the unreliable person (rumors and formal the descendent one, but of regular way in amount and occasional form, they do not have communication plans and they fail to take advantage of the use of Internet. The elaboration of a plan of communications was recommended, according to the necessities of each union.

  12. Students' communicative competence

    Directory of Open Access Journals (Sweden)

    Šafranj Jelisaveta

    2009-01-01

    Full Text Available Communicative competence is the ability to send messages which promote attainment of goals while maintaining social acceptability. Competent communicators attempt to align themselves with each others goals and methods to produce a smooth, productive and often enjoyable dialogue. The aim of this research was to investigate self-perceived communicative competence (SPCC of students of Engineering Management in General English and English for Specific Purposes (ESP. A longitudinal study was carried out starting with the first year students at the Faculty of Technical Sciences in Novi Sad and was repeated with the same sample of students during their second and third year of study. Participation was voluntary and took place during regular class time. The measure of communicative competence employed was the Self-perceived Communication Competence Scale. The results of the study indicated that differences in SPCC between the years do exist. The SPCC gradually improved between the first, the second and the third year. The research was also motivated by gaining better overview of the teaching activity. An anonymous questionnaire provided many useful hints and ideas for further work and thus, language teacher made a thorough analysis of the overall teaching procedure. However, it is essential to get some feedback and talk to students in order to evaluate both them and ourselves as well as the teaching syllabus.

  13. Apologies in business communication

    Directory of Open Access Journals (Sweden)

    Jūratė Ruzaitė

    2007-05-01

    Full Text Available The aim of the present paper is to examine the routine of apologizing in spoken business communication. Being face-threatening acts, apologies are of special importance in communication. Since apologies express sincerity and are remedial acts, apologizing helps to enhance mutual respect and to keep the relationship between colleagues stable, which is especially important in business communication. The present analysis focuses on four main expressions of explicit apologies, i.e. apologies with sorry, I apologise, pardon and excuse me. The data have been obtained from the sub-corpus of the British National Corpus, which includes transcripts of business communication and amounts to 1,321,844 words. The analysis accounts for the general frequency of different forms of apology in business communication as well as their frequency in relation to gender. The paper also focuses on the most typical patterns of apologies and argues that apologies range from neutral to highly emphatic or tentative. Finally, the present analysis investigates what is commonly apologised for in business settings.

  14. Communication with patients and colleagues

    DEFF Research Database (Denmark)

    Nørgaard, Birgitte

    2012-01-01

    Although patient-centred communication has provided a focus point in health care for many years, patient surveys continuously reveal serious communication problems as experienced by patients, due to poor communication. Likewise, poor inter-collegial communication can cause problems for both health...... care staff and patients. So, knowing that patient-centred communication and good inter-collegial communication is for the benefit of both health professionals and patients, the relevance of improving health care professionals' communication skills and investigating the effect on both professionals...

  15. Communication technology update and fundamentals

    CERN Document Server

    Grant, August E

    2010-01-01

    New communication technologies are being introduced at an astonishing rate. Making sense of these technologies is increasingly difficult. Communication Technology Update and Fundamentals is the single best source for the latest developments, trends, and issues in communication technology. Featuring the fundamental framework along with the history and background of communication technologies, Communication Technology Update and Fundamentals, 12th edition helps you stay ahead of these ever-changing and emerging technologies.As always, every chapter ha

  16. Feasible quantum communication complexity protocol

    International Nuclear Information System (INIS)

    Galvao, Ernesto F.

    2002-01-01

    I show that a simple multiparty communication task can be performed more efficiently with quantum communication than with classical communication, even with low detection efficiency η. The task is a communication complexity problem in which distant parties need to compute a function of the distributed inputs, while minimizing the amount of communication between them. A realistic quantum optical setup is suggested that can demonstrate a five-party quantum protocol with higher-than-classical performance, provided η>0.33

  17. Visual communication and terminal equipment

    International Nuclear Information System (INIS)

    Kang, Cheol Hui

    1988-06-01

    This book is divided two parts about visual communication and terminal equipment. The first part introduces visual communication, which deals with foundation of visual communication, technique of visual communication, equipment of visual communication, a facsimile and pictorial image system. The second part contains terminal equipment such as telephone, terminal equipment for data transmission on constitution and constituent of terminal equipment for data transmission, input device and output device, terminal device and up-to-date terminal device.

  18. Visual communication and terminal equipment

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Cheol Hui

    1988-06-15

    This book is divided two parts about visual communication and terminal equipment. The first part introduces visual communication, which deals with foundation of visual communication, technique of visual communication, equipment of visual communication, a facsimile and pictorial image system. The second part contains terminal equipment such as telephone, terminal equipment for data transmission on constitution and constituent of terminal equipment for data transmission, input device and output device, terminal device and up-to-date terminal device.

  19. Management & Communication Training

    CERN Multimedia

    2006-01-01

    Please check our Web site to find out the number of places available which may vary. Calendar of courses for May to June 2006 Management Curriculum 1st semester 2006 Titles Dates language CDP for Supervisors & section Leaders - part 2 2, 3 May English Personal Awareness & Impact 9, 10, 11 May Bilingual CDP pour superviseurs & chefs de section - part 2 11, 12 mai français Introduction to Leadership 17, 18, 19 May English Communicating Effectively - Residential 14, 15, 16 June Bilingual CDP for Group Leaders - part 2 19, 20, 21 June Bilingual Project Management 19, 20, 21 June Bilingual Personal Awareness & Impact - Follow-up 19, 20 June bilingual Leadership Competencies 27, 28 June Bilingual Communication curriculum 1st semester 2006 Titles Dates language Personal Awareness & Impact 9, 10, 11 May Bilingual Personal Awareness & Impact - Follow-up 19, 20 June Bilingual Communicating Effectively 15, 16 May &...

  20. Crisis Communication and Social

    DEFF Research Database (Denmark)

    Tække, Jesper

    2017-01-01

    The academic field of crisis communication is more relevant than ever due to the digital media revolution, setting new standards for how to manage criticism and crises. This paper presents a systems theoretical approach to crisis communication in the age of digital media with a special regard...... to social media. The paper shows that the recent changes in the media environment require that organizations be more observant, reflected and responsive to the public opinion. Correspondingly, organizations need to engage in strategic impression management with the aim to be, or to be observed to be, more...... consistent with their communicated values and strategies, thus managing to appear as trustworthy in a hyper-dynamic social surrounding world. Copyright © 2017 John Wiley & Sons, Ltd....

  1. Communication as practice

    DEFF Research Database (Denmark)

    Gholamian, Jamshid

    2014-01-01

    sort of human activity also include communication as practice. Inspired by Bakhtin, I believe that dialogical relationship is almost a universal phenomenon that permeates all human speech and in general all relationships and manifestations of human life, and "everything in life is dialogue", (Dysthe...... of communicational practices within conversations contexts. Based on Bakhtin’s thought, I understand any conversation as a sociocultural communicative practice. In this concept, the focus will be on how participants via interaction create meaning. In order to elaborate and examine these notions, I will include some......According to Schatzki "Practice" brings into view activities which are situated, corporeal, and shaped by habits without reflection. This notion has been extraordinarily successful and has now been extended to cover every sort of human activity” (Schatzki 2001:2). And I would like to add that every...

  2. Experience Communication and Aesthetics

    DEFF Research Database (Denmark)

    Thorlacius, Lisbeth

    to user aspect (web 2.0), the personal engagement or the community spirit. This increasing demand of experiences reflects the postmodern cultural trends where rules for how to think and behave no longer exist. This results in individualism, where the identity of the human being has changed from something......-actualization. The individualization of the human being can lead to loneliness and a need of participating in communities as a replacement of an overall fixed point in one's life. (Anthony Giddens, 1990, 1991; Zygmunt Bauman, 1997; Carsten René Jørgensen, 2002). The field of communication is consequently experiencing a great......In this article the term "experience communication" will be introduced and discussed. It will be illustrated how different concepts of aesthetical experiences are an integrated part of experience communication and how these concepts are produced within the industries of consumerism, branding...

  3. Quantum communication with photons

    International Nuclear Information System (INIS)

    Tittel, W.

    2005-01-01

    Full text: The discovery that transmission of information encoded into single quantum systems enables new forms of communication let to the emergence of the domain of quantum communication. During the last ten years, various key experiments based on photons as carrier of the quantum information have been realized. Today, quantum cryptography systems based on faint laser pulses can be purchased commercially, bi-partite entanglement has been distributed over long distances and has been used for quantum key distribution, and quantum purification, teleportation and entanglement swapping have been demonstrated. I will give a general introduction into this fascinating field and will review experimental achievements in the domain of quantum communication with discrete two-level quantum systems (qubits) encoded into photons. (author)

  4. Relativity of Visual Communication

    Directory of Open Access Journals (Sweden)

    Arto Mutanen

    2016-03-01

    Full Text Available Communication is sharing and conveying information. In visual communication especially visual messages have to be formulated and interpreted. The interpretation is relative to a method of information presentation method which is human construction. This holds also in the case of visual languages. The notions of syntax and semantics for visual languages are not so well founded as they are for natural languages. Visual languages are both syntactically and semantically dense. The density is connected to the compositionality of the (pictorial languages. In the paper Charles Sanders Peirce’s theory of signs will be used in characterizing visual languages. This allows us to relate visual languages to natural languages. The foundation of information presentation methods for visual languages is the logic of perception, but only if perception is understood as propositional perception. This allows us to understand better the relativity of information presentation methods, and hence to evaluate the cultural relativity of visual communication.

  5. Innovating science communication

    CERN Document Server

    AUTHOR|(CDS)2051192; The ATLAS collaboration; Marcelloni De Oliveira, Claudia; Shaw, Kate

    2016-01-01

    The ATLAS Education & Outreach project has, over the years, developed a strong reputation for supporting innovation. Animated event displays, musical CDs, 3d movies, 3-storey murals, photo books, data sonifications, multi-media art installations, pub slams, masterclasses, documentaries, pop-up books, LEGO® models, and virtual visits are among the many diverse methods being exploited to communicate to the world the goals and accomplishments of the ATLAS Experiment at CERN. This variety of creativity and innovation does not pop out of a vacuum. It requires underlying motivation by the collaboration to communicate with the public; freedom and encouragement to do so in a creative manner; and a support structure for developing, implementing and promoting these activities. The ATLAS Outreach project has built this support structure on a well-defined communication plan, high-quality content, and effective delivery platforms. Most importantly, implementation of the program has been based on the effective engagem...

  6. Communication of the Organization

    Directory of Open Access Journals (Sweden)

    Wojciech Słomski

    2008-07-01

    Full Text Available Communication always takes place by means of symbols. Information must be coded by the sender, i.e. expressed by the use of symbols (mostly language symbols, and then decoded by the recipient. The process of message decoding may be divided into two stages: the acquisition and the interpretation of the message, so-called "understanding" through the attaching of the meaning to symbols, which made up the message. Itself the understanding of the message is a not a sufficient condition of communication, as it may happen so, that the recipient interprets (understands the message in a more or less different way from what the sender intended to transfer, what in practice may lead to the consequences more or less similar to the total impossibility of decoding the message. We may speak about communication only if the meanings attached by the sender to the individual symbols are close or identical to the meanings attached to these symbols by the recipient.

  7. Communication: I like

    CERN Multimedia

    Staff Association

    2015-01-01

    To fulfill its mission to represent CERN personnel with the Management and the Member States, the Staff Council has set up a series of Commissions: employment conditions, pensions, legal matters, social protection, health and safety, InformAction, CAPA (individual cases) and, more recently, Media-Com. As its name suggests the Media-Com Commission deals with all matters of communication. The mandate of the new Commission is to implement and optimize the communication channels that the Staff Association uses to keep you informed. To attract the greatest number of people, Media-Com operates through multiple communication channels, such as articles in the Echo, the Staff Association information bulletin, the Staff Association website (http://staff- association.web.cern.ch/), Facebook, and, more recently, the intra-CERN Social platform. The Social platform is a discussion forum, for exchanging ideas, expressing views, reacting to, and commenting on current events of the Staff Association. To participa...

  8. Underwater wireless communication system

    International Nuclear Information System (INIS)

    Goh, J H; Shaw, A; Al-Shamma'a, A I

    2009-01-01

    Underwater communication has a range of applications including remotely operated vehicle (ROV) and autonomous underwater vehicle (AUV) communication and docking in the offshore industry. Current underwater transmission techniques is primarily utilise sound waves for large distance at lower frequencies and the velocity of sound in water is approximately 1500m/s the resultant communications have problems with multi-path propagation and low bandwidth problems. The use of electromagnetic (EM) techniques underwater has largely been overlooked because of the attenuation due to the conductivity of seawater. However, for short range applications, the higher frequencies and much higher velocity can prove advantageous. This paper will outline a project which will utilise recent investigations that demonstrate EM wave propagation up to the MHz frequency range is possible in seawater.

  9. WHO risk communication seminar

    International Nuclear Information System (INIS)

    1998-01-01

    The International EMF project organised by the WHO is now entering its third year. In addition to providing authoritative reviews of the scientific literature on the health effects of exposure to electric and magnetic fields, a key objective of the five year programme is to provide information on the perception, communication and management of risk, and how this relates to electric and magnetic fields. To this end, an International seminar on: Risk perception, risk communication and its application to EMF exposure, was held in Vienna on 22-23 October last year, bringing togehter an array of speakers from around the world to talk about perceptions of risk, how best to communicate risks to the public and present some practical examples. (author)

  10. Language, Communication and Style

    Directory of Open Access Journals (Sweden)

    Stăncuţa Ramona DIMA-LAZA

    2011-01-01

    Full Text Available Intercultural language and communication skills vary across culture. Blunders are the result of an improper understanding of other nation’s language, non-verbal communication or customs and traditions. The present paper represents an incursion into the world of inaccurate translations and misinterpretations caused by a lack of ability to overcome cultural and language barriers. It also provides solutions for such problems, exemplifying with relevant situations. It informs the reader about writing principles and style, examining the outcome of conveying an inaccurate message. People write, deliver speeches or communicate for different purposes: to learn something, to entertain or to make money. Whether it is about one reason or another, the basic idea is to comply with certain language codes in order to avoid cultural conflicts.

  11. Inhibition of PTP1B disrupts cell-cell adhesion and induces anoikis in breast epithelial cells.

    Science.gov (United States)

    Hilmarsdottir, Bylgja; Briem, Eirikur; Halldorsson, Skarphedinn; Kricker, Jennifer; Ingthorsson, Sævar; Gustafsdottir, Sigrun; Mælandsmo, Gunhild M; Magnusson, Magnus K; Gudjonsson, Thorarinn

    2017-05-11

    Protein tyrosine phosphatase 1B (PTP1B) is a well-known inhibitor of insulin signaling pathways and inhibitors against PTP1B are being developed as promising drug candidates for treatment of obesity. PTP1B has also been linked to breast cancer both as a tumor suppressor and as an oncogene. Furthermore, PTP1B has been shown to be a regulator of cell adhesion and migration in normal and cancer cells. In this study, we analyzed the PTP1B expression in normal breast tissue, primary breast cells and the breast epithelial cell line D492. In normal breast tissue and primary breast cells, PTP1B is widely expressed in both epithelial and stromal cells, with highest expression in myoepithelial cells and fibroblasts. PTP1B is widely expressed in branching structures generated by D492 when cultured in 3D reconstituted basement membrane (3D rBM). Inhibition of PTP1B in D492 and another mammary epithelial cell line HMLE resulted in reduced cell proliferation and induction of anoikis. These changes were seen when cells were cultured both in monolayer and in 3D rBM. PTP1B inhibition affected cell attachment, expression of cell adhesion proteins and actin polymerization. Moreover, epithelial to mesenchymal transition (EMT) sensitized cells to PTP1B inhibition. A mesenchymal sublines of D492 and HMLE (D492M and HMLEmes) were more sensitive to PTP1B inhibition than D492 and HMLE. Reversion of D492M to an epithelial state using miR-200c-141 restored resistance to detachment induced by PTP1B inhibition. In conclusion, we have shown that PTP1B is widely expressed in the human breast gland with highest expression in myoepithelial cells and fibroblasts. Inhibition of PTP1B in D492 and HMLE affects cell-cell adhesion and induces anoikis-like effects. Finally, cells with an EMT phenotype are more sensitive to PTP1B inhibitors making PTP1B a potential candidate for further studies as a target for drug development in cancer involving the EMT phenotype.

  12. Near field communications handbook

    CERN Document Server

    Ahson, Syed A; Furht, Borko

    2011-01-01

    Near Field Communication, or NFC, is a short-range high frequency wireless communication technology that enables the exchange of data between devices over about a decimeter. The technology is a simple extension of the ISO 14443 proximity-card standard (contact less card, RFID) that combines the interface of a smart card and a reader into a single device with practical implications. A complete reference for NFC, this handbook provides technical information about all aspects of NFC, as well as applications. It covers basic concepts as well as research grade material and includes a discussion of

  13. Culture, technology, communication

    DEFF Research Database (Denmark)

    Ess, Charles; Sudweeks, Fay

    The first book-length anthology to collect some of the most significant culturally-oriented research and scholarship on CMC from the biennial conference series "Cultural Attitudes towards Technology and Communication" (CATaC). The collection is significant for its contribution towards calling...... attention to the role of culturally-variable dimensions, including communication preferences, in the design, implementation, and use of ICTs - and thereby helping to bring into the mainstream of related scholarship and research (e.g., HCI, etc.) what was then a novel perspective and series of questions...

  14. Communication grounding facility

    International Nuclear Information System (INIS)

    Lee, Gye Seong

    1998-06-01

    It is about communication grounding facility, which is made up twelve chapters. It includes general grounding with purpose, materials thermal insulating material, construction of grounding, super strength grounding method, grounding facility with grounding way and building of insulating, switched grounding with No. 1A and LCR, grounding facility of transmission line, wireless facility grounding, grounding facility in wireless base station, grounding of power facility, grounding low-tenton interior power wire, communication facility of railroad, install of arrester in apartment and house, install of arrester on introduction and earth conductivity and measurement with introduction and grounding resistance.

  15. Language in Web Communication

    DEFF Research Database (Denmark)

    Toft, Birthe

    2012-01-01

    Having taught and carried out research in LSP and business communication for many years, I have come across, again and again, the problems arising from the inferior status of language in the business environment. Being convinced that it does not have to be so, instead of going on trying to convince...... non-linguistically trained colleagues of the importance of language via the usual arguments, I suggest that we let them experience the problems arising from the non-recognition of the importance of language via a Web communication crash course, inspired by a course taught to BA students...

  16. Grammar and Communication

    Institute of Scientific and Technical Information of China (English)

    刘辉

    2007-01-01

    Instead of being a boring subject, grammar is in fact one of the most exciting, creative, relevant subjects. It is sometimes described as the skeleton of a language, but it is much more than bones. It is the language's heartbeat, for without grammar; there can be no meaningful or effective communication. And grammar has different definitions and categories according to different contexts. By first reviewing the past linguists, especially those grammarians and their research, the paper makes some comparisons between some categories of grammar and puts forward that there is no 'good' or 'bad' grammar but knowing grammar or knowing about grammar really has a close relationship with effective communication.

  17. Communications options for teleoperations

    International Nuclear Information System (INIS)

    Springthorpe, R.T.

    1991-08-01

    TELEMAN is a programme of research work on remote handling in hazardous or disordered nuclear environments, carried out for the European Atomic Agency Community by a number of participants, part funded by the CEC. The objective is to develop advanced tele-operated robots for users in the nuclear industry to contribute to safety and profitability. A study performed by AEA Technology in 1989 for the TELEMAN programme examined communications standards and made recommendations where possible. It was recognised that a control architecture needed to be defined before determining which communications standards are appropriate. Several developing areas were recommended for further study and the results of this study are reported here. (author)

  18. Computer-communication networks

    CERN Document Server

    Meditch, James S

    1983-01-01

    Computer- Communication Networks presents a collection of articles the focus of which is on the field of modeling, analysis, design, and performance optimization. It discusses the problem of modeling the performance of local area networks under file transfer. It addresses the design of multi-hop, mobile-user radio networks. Some of the topics covered in the book are the distributed packet switching queuing network design, some investigations on communication switching techniques in computer networks and the minimum hop flow assignment and routing subject to an average message delay constraint

  19. Social communication impairments: pragmatics.

    Science.gov (United States)

    Russell, Robert L

    2007-06-01

    Social communication or pragmatic impairments are characterized and illustrated as involving inappropriate or ineffective use of language and gesture in social contexts. Three clinical vignettes illustrate different pragmatic impairments and the wealth of diagnostic information that can be garnered from observation of a child's social communication behavior. Definitions of, and developmental milestones in, domains of pragmatic competence are provided. Several screening instruments are suggested for use in assessing pragmatic competence within the time-frame of a pediatric examination. Frequent comorbid psychiatric conditions are described and a sample of current neurobiologic research is briefly summarized.

  20. Digital communication device

    DEFF Research Database (Denmark)

    2005-01-01

    The invention concerns a digital communication device like a hearing aid or a headset. The hearing aid or headset has a power supply, a signal processing device, means for receiving a wireless signal and a receiver or loudspeaker, which produces an audio signal based on a modulated pulsed signal...... point is provided which is in electrical contact with the metal of the metal box and whereby this third connection point is connected to the electric circuitry of the communication device at a point having a stable and well defined electrical potential. In this way the electro-and magnetic radiation...

  1. Man - Machine Communication

    CERN Document Server

    Petersen, Peter; Nielsen, Henning

    1984-01-01

    This report describes a Man-to-Machine Communication module which together with a STAC can take care of all operator inputs from the touch-screen, tracker balls and mechanical buttons. The MMC module can also contain a G64 card which could be a GPIB driver but many other G64 cards could be used. The soft-ware services the input devices and makes the results accessible from the CAMAC bus. NODAL functions for the Man Machine Communication is implemented in the STAC and in the ICC.

  2. Communication in different keys

    International Nuclear Information System (INIS)

    Souwer, Corinne

    1995-01-01

    This paper is based on a study for which the research has been conducted by Esther van der Draai, trainee at ECN - Nuclear Energy, Dutch member of the NucNet board, delegation member of the European Task Force Group - 10th Anniversary of Chernobyl. The complete study is presented to WIN. It explains how to attune communication to the target group, and discusses the communication theory analogue language, which does not only include the typical non-verbal signals, such as eye contact, facial expression, gestures, etc., but also smiling, blushing, sighing, clothing, smell. In short, analogue language is always there and always influences other parties

  3. Wireless Cellular Mobile Communications

    Directory of Open Access Journals (Sweden)

    V. Zalud

    2002-12-01

    Full Text Available In this article is briefly reviewed the history of wireless cellularmobile communications, examined the progress in current secondgeneration (2G cellular standards and discussed their migration to thethird generation (3G. The European 2G cellular standard GSM and itsevolution phases GPRS and EDGE are described somewhat in detail. Thethird generation standard UMTS taking up on GSM/GPRS core network andequipped with a new advanced access network on the basis of codedivision multiple access (CDMA is investigated too. A sketch of theperspective of mobile communication beyond 3G concludes this article.

  4. Setting the research agenda for governmental communication

    NARCIS (Netherlands)

    M. Vos

    2006-01-01

    The Research Group for Governmental Communication has carried out a trend study of governmental communication within The Netherlands (1). Research topics were: the major tasks for communication, current issues, profiling the communication department, and policy plans for communication. Another study

  5. Are Communication Strategies Teachable?

    Science.gov (United States)

    Lewis, Samantha

    2011-01-01

    This article discusses the teachability of communication strategies in the EFL classroom. As well as reflecting on the nature of speech production in the mother tongue, it looks at some of the difficulties encountered when speaking in a foreign language and the inherent difficulties in "teaching" speaking as a skill. It focuses on different types…

  6. Risk communication importance

    Energy Technology Data Exchange (ETDEWEB)

    Cunha, Raquel Dalledone Siqueira da; Andrade, Delvonei Alves de, E-mail: raqueldalledonesiqueira@gmail.com, E-mail: delvonei@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2013-07-01

    Risk Communication has shown its importance in the elaboration of emergency plans in the Chemical industry. In the 90's, the UNEP developed the APELL (Awareness and Preparedness for Emergency at Local Level) plan, a risk management methodology used by dangerous chemical facilities. The methodology comprises the commitment of both Government and the community located in the risk area in the development of the emergency plan. In the nuclear sector, there is no similar methodology developed so far. However, establishing a communication channel between the nuclear segment and the community is essential. In Brazil, the construction of Angra 3 and the RMB (Multi Purpose Reactor) project stand as nuclear initiatives that improve the importance of a good communication to the public. Security issues of these projects are natural sources of concernment to the public, which is aggravated by events such as the Fukushima disaster. Without an effective communication about what means the presence of nuclear plants and reactors in a specific area, the interested public will only have an alarmist vision of the subject, given by those against these facilities. (author)

  7. Communication in Practice

    Energy Technology Data Exchange (ETDEWEB)

    Drottz-Sjoeberg, Britt-Marie [Norwegian Univ. of Science and Technology, NTNU, Trondheim (Norway). Dept. of Psychology

    2001-07-01

    The paper presents results from the 'Communication 2000' project within the Nordic Nuclear Safety Research (NKS) framework which aimed at developing methods as well as knowledge related to problems in risk communication. Focus groups and questionnaires were used to explicitly pinpoint the problems encountered when informing about or discussing risk and technologically advanced information (e.g. PSA-results) relative the public and across professional groups with different types of expertise. Personnel at a nuclear power plant and politicians of a local safety board provided their views of essential communication problems related to their work tasks in focus group discussions. Central topics that emerged from these discussions were later used in a questionnaire study, distributed to similar groups of power plant personnel, and politicians and administrators, in the local community. Some results are presented, together with a comparison of the two modes of investigating what is problematic in risk communication (e.g. focus groups vs. questionnaires). The difficulties involved in establishing a similar understanding of a phenomenon is addressed in the discussion.

  8. Risk communication importance

    International Nuclear Information System (INIS)

    Cunha, Raquel Dalledone Siqueira da; Andrade, Delvonei Alves de

    2013-01-01

    Risk Communication has shown its importance in the elaboration of emergency plans in the Chemical industry. In the 90's, the UNEP developed the APELL (Awareness and Preparedness for Emergency at Local Level) plan, a risk management methodology used by dangerous chemical facilities. The methodology comprises the commitment of both Government and the community located in the risk area in the development of the emergency plan. In the nuclear sector, there is no similar methodology developed so far. However, establishing a communication channel between the nuclear segment and the community is essential. In Brazil, the construction of Angra 3 and the RMB (Multi Purpose Reactor) project stand as nuclear initiatives that improve the importance of a good communication to the public. Security issues of these projects are natural sources of concernment to the public, which is aggravated by events such as the Fukushima disaster. Without an effective communication about what means the presence of nuclear plants and reactors in a specific area, the interested public will only have an alarmist vision of the subject, given by those against these facilities. (author)

  9. Communicating with recreationists

    Science.gov (United States)

    J. Alan Wagar

    1971-01-01

    Recreationists are free to ignore many of a land manager's communication efforts. Greatest effectiveness can be expected for presentations that are dynamic and are tailored to the interests and other characteristics of selected visitor groups that permit participation and reward learning, and that provide both an idea of what is coming and a framework to give it...

  10. Wireless Communication Technologies

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Wireless Communication Technologies. Since 1999, the wireless LAN has experienced a tremendous growth. Reasons: Adoption of industry standards. Interoperability testing. The progress of wireless equipments to higher data rates. Rapid decrease in product ...

  11. DYMAC communications system

    Energy Technology Data Exchange (ETDEWEB)

    Lindsey, K.A.

    1980-01-01

    The DYMAC Communications System is part of a nuclear safeguards system called DYMAC - short for DYnamic Materials ACcountability - that gathers accountability information at the Los Alamos Scientific Laboratory (LASL) Plutonium Processing Facility. The communications system handles transmissions between data-entry terminals and nondestructive assay (NDA) instruments located in the facility, and a computer located in an adjacent building. System design emphasizes reliability rather than high speed to ensure the integrity of data transmissions. This manual is directed toward the person responsible for maintaining the DYMAC Communication System. It describes the components that make up the communications network, explains how they operate, and gives detailed information about all of the connections. Many of the system components are commercially available; some have been modified at LASL for DYMAC purposes; others were designed and fabricated at LASL. This manual provides circuit diagrams for all of the LASL modifications and LASL-fabricated equipment. In addition, it provides a series of procedures for tracing cables, reconfiguring various parts of the system, testing data transmissions, and troubleshooting malfunctions.

  12. Media Differences in Communication

    NARCIS (Netherlands)

    Raine, Roxanne B.; Raine, Roxanne B.; Esposito, A.; Campbell, N.; Vogel, C.; Hussain, A.; Nijholt, Antinus

    2010-01-01

    With the ever-growing ubiquity of computer-mediated communication, the application of language research to computer-mediated environments becomes increasingly relevant. How do overhearer effects, discourse markers, differences for monologues and dialogues, and other verbal findings transmute in the

  13. Is communication really food?

    Directory of Open Access Journals (Sweden)

    Sandra Veinberg

    2015-10-01

    Full Text Available This paper examines a new doctrine for communication. It argues that effective communications are as important to our well being and happiness as the food we put into our bodies. ‘It can either be healthy (and nourishing or toxic (and destructive,’ notes the Zen master and Buddhist monk, Thich Nhat Hanh. To examine this theory I decided to test my students. Use was made of a non-proportional stratified sample of younger adults, a total of 200 students who were involved in the survey study. Research is also based on an analysis of a qualitative research programme (a qualitative study which involved 200 questionnaire texts that were set using two methods: critical discourse analysis and context. The results of my research show that students stressed that they were not using traditional forms of media, that the younger reader wants dialogue with the author or journalist, and that they tend to favour relationship-based communications which are offered by social media. My conclusions show that social media is regarded as ‘an anti-loneliness tool‘, and that it encourages a dialogue between the transmitter and the reader and allows a dialogue between them both. Language acts here as a relationship-building resource and shows a level of interaction between text and participants. This shows that, via social media, the internet provides a special form of communication which compensates the audience as might a gourmet restaurant.

  14. A communication quandry

    NARCIS (Netherlands)

    Frewer, L.J.

    2010-01-01

    Chemistry & Industry 25 January 2010 Comment A communication quandry If nanotechnology is to avoid the fate that befell GM crops in Europe then regulators will need to be honest with the general public about the risks & benefits, says Lynn Frewer There is increasing investment in the private

  15. THE ENVIRONMENTAL COMMUNICATION FORUM

    African Journals Online (AJOL)

    could enable the more effective communication of envi:onmental issues, not forgetting the importance ... headquarters, when she explained the psychology used to try to persuade people to care for their environ- ment. ... offering a facility if those to whom it is offered are unaware of its existence, or of its value. This the forum ...

  16. Decentralized control and communication

    Czech Academy of Sciences Publication Activity Database

    Bakule, Lubomír; Papík, Martin

    2012-01-01

    Roč. 36, č. 1 (2012), s. 1-10 ISSN 1367-5788 R&D Projects: GA MŠk(CZ) LG12014 Institutional research plan: CEZ:AV0Z10750506 Keywords : decentralization * communication * large-scale complex systems Subject RIV: BC - Control Systems Theory Impact factor: 1.289, year: 2012

  17. Communication-Based Classrooms.

    Science.gov (United States)

    Kretschmer, Richard R., Jr.; Kretschmer, Laura W.

    1995-01-01

    Addresses three issues in developing the communication abilities of students with hearing impairments: (1) teaching the six primary discourse functions (narration, explanation, contrast-comparison, instruction giving, persuasion, and negotiation); (2) tensions between time needed for language learning and covering curriculum content; and (3)…

  18. Naming as Strategic Communication

    DEFF Research Database (Denmark)

    Schmeltz, Line; Kjeldsen, Anna Karina

    2016-01-01

    This article presents a framework for understanding corporate name change as strategic communication. From a corporate branding perspective, the choice of a new name can be seen as a wish to stand out from a group of similar organizations. Conversely, from an institutional perspective, name change...

  19. Graphic Communications. Curriculum Guide.

    Science.gov (United States)

    North Dakota State Board for Vocational Education, Bismarck.

    This guide provides the basic foundation to develop a one-semester course based on the cluster concept, graphic communications. One of a set of six guides for an industrial arts curriculum at the junior high school level, it suggests exploratory experiences designed to (1) develop an awareness and understanding of the drafting and graphic arts…

  20. INFORMATION AND COMMUNICATION

    African Journals Online (AJOL)

    USER

    and constantly used communication models of mobile telephony 100%, electronic-mail, 65% than other forms ... services offered, and providing marketing ... questions. FINDINGS. NO. OF ICT LITERATES. Name of Institutions. No. of. Librarians. On-line. Network. Internet E-mail. Mobile. Telephoning. Fax. Machine. DELSU ...

  1. PERSONAL VERSUS MASS COMMUNICATION

    OpenAIRE

    Girboveanu Sorina

    2007-01-01

    From the comparison of the various aspects of advertising and personal selling, it can be seen that personal selling is a more effective and powerful communication tool than advertising, but advertising is more time and cost efficient than personal selling. Thus advertising and personal selling are tools at the disposal of a marketer and subjects to a firm’s overall objectives.

  2. Processes of Mass Communication.

    Science.gov (United States)

    Channey, David

    This sociological treatment of mass communications analysis first discusses the theories of audience behavior, then turns to the organization of media production, and closes with a study of performance. The book covers audience needs and gratifications, the history of British press and broadcasting results of systems of media distribution, the…

  3. Connectivist Communication Networks

    Science.gov (United States)

    Waßmann, Ingolf; Nicolay, Robin; Martens, Alke

    2016-01-01

    Facing the challenges of the digital age concerning lifelong learning, this contribution presents an approach to dynamically establish Connectivist communication networks. According the statement "the pipe is more important than the content within the pipe" by Georg Siemens, learning in digital age includes the connection of people to…

  4. SHORT COMMUNICATION POTENTIOMETRIC DETERMINATION ...

    African Journals Online (AJOL)

    a

    SHORT COMMUNICATION. POTENTIOMETRIC DETERMINATION OF K+ IONS USING A K+-SELECTIVE. ELECTRODE WITH MACROCYCLIC LIQUID MEMBRANE. Cezar Spinu*, Marian Isvoranu, Maria Pleniceanu and Cristian Tigae. Faculty of Chemistry, University of Craiova, A.I. Cuza 13, Craiova, Romania. (Received ...

  5. Communication Network Analysis Methods.

    Science.gov (United States)

    Farace, Richard V.; Mabee, Timothy

    This paper reviews a variety of analytic procedures that can be applied to network data, discussing the assumptions and usefulness of each procedure when applied to the complexity of human communication. Special attention is paid to the network properties measured or implied by each procedure. Factor analysis and multidimensional scaling are among…

  6. Communication in Symbolic Play.

    Science.gov (United States)

    Umek, Ljubica Marjanovic; Musek, Petra Lesnik; Kranjc, Simona

    2001-01-01

    Analyzed records of Slovene children's speech from a linguistic point of view and established differences in communication patterns with regard to the children's ages and the type of symbolic play. Found a shift in play from make-believe with regard to objects to roleplay related to social context. The older the child, the more language functions…

  7. European environmental communication networks

    International Nuclear Information System (INIS)

    Plesnikova, T.

    2005-01-01

    The goal of this presentation is apprise of special community - representatives of state and public administration, self-administration, workers of scientific institutes, schools, private companies and next privies subjects of areas of the environment with possibilities of access to actual environmental information by the Internet. Web-sites of environmental communication networks with data about the environment are presented

  8. English for Business Communication

    Science.gov (United States)

    Bhatia, Vijay K.; Bremner, Stephen

    2012-01-01

    The concept of Business English has undergone some major shifts in the last few years because of a number of developments, such as advances in genre theory and the coming together of English for Business Purposes and Business Communication, inspired by the realization that there is a gap to be bridged between the academy and the globalized…

  9. Communicating Process Achitectures 2005

    NARCIS (Netherlands)

    Groothuis, M.A.; Broenink, Johannes F.; Roebbers, Herman W.; Sunters, Johan P.E.; Welch, Peter H.; Wood, David C.

    The awareness of the ideas characterized by Communicating Processes Architecture and their adoption by industry beyond their traditional base in safety-critical systems and security is growing. The complexity of modern computing systems has become so great that no one person – maybe not even a small

  10. INFORMATION AND COMMUNICATION

    African Journals Online (AJOL)

    USER

    NIGERIAN ACADEMIC LIBRARIES PROSPECTS AND PROBLEMS. BY. MARTHA J. ELISHA. KASHIM IBRAHIM LIBRARY ... transmit or receive information electronically in a digital form. For example, personal computer, digital television ... Given the great advances being made in the field of communication, there are great.

  11. The Challenges in Communication

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. The Challenges in Communication. The conflict between connection oriented and connectionless. The seamless integration needs of broadcast, unicast and multicast in the midst growing security concerns. Like Indian roads – need to carry voice, internet traffic, video ...

  12. Communicating with Professionals

    Medline Plus

    Full Text Available ... to your doctor, nurse, pharmacist, dietitian, physical therapist, exercise physiologist or other healthcare professionals. Find a list of questions to ask at your next appointment . Healthcare professionals talk about why good communication is important A patient describes how he prepares for office ...

  13. DYMAC communications system

    International Nuclear Information System (INIS)

    Lindsey, K.A.

    1980-01-01

    The DYMAC Communications System is part of a nuclear safeguards system called DYMAC - short for DYnamic Materials ACcountability - that gathers accountability information at the Los Alamos Scientific Laboratory (LASL) Plutonium Processing Facility. The communications system handles transmissions between data-entry terminals and nondestructive assay (NDA) instruments located in the facility, and a computer located in an adjacent building. System design emphasizes reliability rather than high speed to ensure the integrity of data transmissions. This manual is directed toward the person responsible for maintaining the DYMAC Communication System. It describes the components that make up the communications network, explains how they operate, and gives detailed information about all of the connections. Many of the system components are commercially available; some have been modified at LASL for DYMAC purposes; others were designed and fabricated at LASL. This manual provides circuit diagrams for all of the LASL modifications and LASL-fabricated equipment. In addition, it provides a series of procedures for tracing cables, reconfiguring various parts of the system, testing data transmissions, and troubleshooting malfunctions

  14. Optimizing Millennials' Communication Styles

    Science.gov (United States)

    Hartman, Jackie L.; McCambridge, Jim

    2011-01-01

    Millennials, those individuals born between 1980 and 2000, compose the largest cohort of college students in the United States. Stereotypical views of millennials characterize them as technologically sophisticated multitaskers, capable of significant contributions to tomorrow's organizations, yet deficient in communication skills. This article…

  15. PAGING IN COMMUNICATIONS

    DEFF Research Database (Denmark)

    2016-01-01

    A method and an apparatus are disclosed for managing paging in a communications system. The method may include, based on a received set of physical resources, determining, in a terminal apparatus, an original paging pattern defining potential time instants for paging, wherein the potential time...... instants for paging include a subset of a total amount of resources available at a network node for paging....

  16. Workplace Communication: Meaningful Messages.

    Science.gov (United States)

    Travis, Lisa; Watkins, Lisa

    This learning module emphasizes workplace communication skills with a special focus on the team environment. The following skills are addressed: speaking with clarity, maintaining eye contact, listening carefully, responding to questions with patience and an open mind, showing a willingness to understand, giving instructions clearly, and…

  17. Communication Technologies for Vehicles

    DEFF Research Database (Denmark)

    Vinel, Alexey

    This book constitutes the proceedings of the 8th International Workshop on Communication Technologies for Vehicles, Nets4Cars/Nets4Trains/Nets4Aircraft 2015, held in Sousse, Tunisia, in May 2015. The 20 papers presented in this volume were carefully reviewed and selected from 27 submissions....... The contributions are organized in topical sections named: road; rail; and air....

  18. Multiple Access Communications

    DEFF Research Database (Denmark)

    This book constitutes the proceedings of the 9th International Workshop on Multiple Access Communications, MACOM 2016, held in Aalborg, Denmark, in November 2016. The 10 full papers presented in this volume were carefully reviewed and selected from 12 submissions. They were organized in topical...

  19. Communication and abnormal behaviour.

    Science.gov (United States)

    Crown, S

    1979-01-01

    In this paper the similarities between normal and abnormal behaviour are emphasized and selected aspects of communication, normal and aberrant, between persons are explored. Communication in a social system may be verbal or non-verbal: one person's actions cause a response in another person. This response may be cognitive, behavioural or physiological. Communication may be approached through the individual, the social situation or social interaction. Psychoanalysis approaches the individual in terms of the coded communications of psychoneurotic symptoms or psychotic behaviour; the humanist-existential approach is concerned more with emotional expression. Both approaches emphasize the development of individual identity. The interaction between persons and their social background is stressed. Relevant are sociological concepts such as illness behaviour, stigma, labelling, institutionalization and compliance. Two approaches to social interactions are considered: the gamesplaying metaphor, e.g. back pain as a psychosocial manipulation--the 'pain game'; and the 'spiral of reciprocal perspectives' which emphasizes the interactional complexities of social perceptions. Communicatory aspects of psychological treatments are noted: learning a particular metaphor such as 'resolution' of the problem (psychotherapy), learning more 'rewarding' behaviour (learning theory) or learning authenticity or self-actualization (humanist-existential).

  20. Information and Communication Technology

    DEFF Research Database (Denmark)

    Kaila, Heidi Kristiina

    2017-01-01

    The emergence and development of the information and communication sector has been rapid in rural Viet Nam over 2006–14, and a true information and communication technology (ICT) revolution has taken place. This chapter examines household ownership and use of ICT. It studies the geographic and de...... wealthier and more educated than households with phones on average, the adoption patterns of these two technologies are very similar. ICT adoption is driven by education and income, as well as wealth and ownership of other technology.......The emergence and development of the information and communication sector has been rapid in rural Viet Nam over 2006–14, and a true information and communication technology (ICT) revolution has taken place. This chapter examines household ownership and use of ICT. It studies the geographic...... and demographic differences across ownership of technology, especially phones and the Internet, and the determinants of ICT adoption. First, it finds that expansion of telephones has been much more rapid than the expansion of the Internet. Second, it finds that even though in 2014 internet users were relatively...

  1. Communication in Practice

    International Nuclear Information System (INIS)

    Drottz-Sjoeberg, Britt-Marie

    2001-01-01

    The paper presents results from the 'Communication 2000' project within the Nordic Nuclear Safety Research (NKS) framework which aimed at developing methods as well as knowledge related to problems in risk communication. Focus groups and questionnaires were used to explicitly pinpoint the problems encountered when informing about or discussing risk and technologically advanced information (e.g. PSA-results) relative the public and across professional groups with different types of expertise. Personnel at a nuclear power plant and politicians of a local safety board provided their views of essential communication problems related to their work tasks in focus group discussions. Central topics that emerged from these discussions were later used in a questionnaire study, distributed to similar groups of power plant personnel, and politicians and administrators, in the local community. Some results are presented, together with a comparison of the two modes of investigating what is problematic in risk communication (e.g. focus groups vs. questionnaires). The difficulties involved in establishing a similar understanding of a phenomenon is addressed in the discussion

  2. Communicating with Professionals

    Medline Plus

    Full Text Available ... to follow-up with your medical team. You can help improve the care you receive at follow-up ... you (or your professionals) want. Simple communication skills can help you get what you need – over the phone, ...

  3. Communication and industrial accidents

    NARCIS (Netherlands)

    As, Sicco van

    2001-01-01

    This paper deals with the influence of organizational communication on safety. Accidents are actually caused by individual mistakes. However the underlying causes of accidents are often organizational. As a link between these two levels - the organizational failures and mistakes - I suggest the

  4. Communicating with Professionals

    Medline Plus

    Full Text Available ... your next appointment . Healthcare professionals talk about why good communication is important A patient describes how he prepares for ... Care of Yourself - Introduction - Coping With Feelings - Reducing Stress - Quitting Smoking ... 8 Low Blood Pressure - When Blood Pressure Is Too Low 9 Tachycardia | Fast Heart Rate 10 ...

  5. Closing the Communication Gap

    Science.gov (United States)

    Walmsley, Angela L. E.

    2011-01-01

    The three generations--Baby Boomer (born between 1946 and 1965), Generation X (born between 1967 and 1975), and Generation Y (born between 1976 and 2000)--have different styles of communication, yet teachers of all ages still have to work together effectively. Teachers can improve their relationships with their colleagues if they understand more…

  6. Political Communication Yearbook 1984.

    Science.gov (United States)

    Sanders, Keith R., Ed.; And Others

    Focusing on current scholarship in the evolving field of political communication, this publication is organized in three sections. Part 1, "Current Perspectives on the Spiral of Silence," features essays by Charles T. Salmon and F. Gerald Kline, Klaus Merten, Carroll J. Glynn and Jack M. McLeod, and a response by the theory's original…

  7. Improving Family Communication.

    Science.gov (United States)

    Medrano, Vilma; Bonilla, Gladys; Hernández, Ericka; Romanjek, Mariana Harnecker; Gómez, Adriana; Hernández, Jasón; Reyes, Marcela Ríos; Lindenberg, Cathy Strachan

    2017-03-01

    TeenSmart International harnesses the power and flexibility of technology to empower youth to take personal responsibility for their health and lifestyle choices. Access to the Internet via mobile phones is often cheaper than paying to connect to a wired broadband service, and in rural areas, mobile networks may be the only means of accessing the Internet. This study assessed the feasibility, acceptability, and impact of "cues to action" or brief motivating cell phone text messages to improve adolescent family communication and relationships. A quasi-experimental design using a voluntary sample of 100 Nicaraguan youth at high risk for poor family communication participated. Pre- and posttest quantitative measures using Student t statistical analysis, a focus group, and a participant testimony provided the evaluation evidence. Findings suggest that there are economic and motivational barriers to the use of text messages, but when barriers are eliminated, the behavioral results are positive. Youth who received two weekly text messages over a 6-month period demonstrated statistically significant improvements in family communication perceptions, attitudes, and behaviors, strengthening their family communications and relationships. Brief and personalized text messaging "cues to action" may be a cost-effective intervention to improve adolescent healthy lifestyle behaviors.

  8. A communication-theory based view on telemedical communication.

    Science.gov (United States)

    Schall, Thomas; Roeckelein, Wolfgang; Mohr, Markus; Kampshoff, Joerg; Lange, Tim; Nerlich, Michael

    2003-01-01

    Communication theory based analysis sheds new light on the use of health telematics. This analysis of structures in electronic medical communication shows communicative structures with special features. Current and evolving telemedical applications are analyzed. The methodology of communicational theory (focusing on linguistic pragmatics) is used to compare it with its conventional counterpart. The semiotic model, the roles of partners, the respective message and their relation are discussed. Channels, sender, addressee, and other structural roles are analyzed for different types of electronic medical communication. The communicative processes are shown as mutual, rational action towards a common goal. The types of communication/texts are analyzed in general. Furthermore the basic communicative structures of medical education via internet are presented with their special features. The analysis shows that electronic medical communication has special features compared to everyday communication: A third participant role often is involved: the patient. Messages often are addressed to an unspecified partner or to an unspecified partner within a group. Addressing in this case is (at least partially) role-based. Communication and message often directly (rather than indirectly) influence actions of the participants. Communication often is heavily regulated including legal implications like liability, and more. The conclusion from the analysis is that the development of telemedical applications so far did not sufficiently take communicative structures into consideration. Based on these results recommendations for future developments of telemedical applications/services are given.

  9. Communication, Technology, Temporality

    Directory of Open Access Journals (Sweden)

    Mark A. Martinez

    2012-08-01

    Full Text Available This paper proposes a media studies that foregrounds technological objects as communicative and historical agents. Specifically, I take the digital computer as a powerful catalyst of crises in communication theories and certain key features of modernity. Finally, the computer is the motor of “New Media” which is at once a set of technologies, a historical epoch, and a field of knowledge. As such the computer shapes “the new” and “the future” as History pushes its origins further in the past and its convergent quality pushes its future as a predominate medium. As treatment of information and interface suggest, communication theories observe computers, and technologies generally, for the mediated languages they either afford or foreclose to us. My project describes the figures information and interface for the different ways they can be thought of as aspects of communication. I treat information not as semantic meaning, formal or discursive language, but rather as a physical organism. Similarly an interface is not a relationship between a screen and a human visual intelligence, but is instead a reciprocal, affective and physical process of contact. I illustrate that historically there have been conceptions of information and interface complimentary to mine, fleeting as they have been in the face of a dominant temporality of mediation. I begin with a theoretically informed approach to media history, and extend it to a new theory of communication. In doing so I discuss a model of time common to popular, scientific, and critical conceptions of media technologies especially in theories of computer technology. This is a predominate model with particular rules of temporal change and causality for thinking about mediation, and limits the conditions of possibility for knowledge production about communication. I suggest a new model of time as integral to any event of observation and analysis, and that human mediation does not exhaust the

  10. Terabit Wireless Communication Challenges

    Science.gov (United States)

    Hwu, Shian U.

    2012-01-01

    This presentation briefly discusses a research effort on Terabit Wireless communication systems for possible space applications. Recently, terahertz (THz) technology (300-3000 GHz frequency) has attracted a great deal of interest from academia and industry. This is due to a number of interesting features of THz waves, including the nearly unlimited bandwidths available, and the non-ionizing radiation nature which does not damage human tissues and DNA with minimum health threat. Also, as millimeter-wave communication systems mature, the focus of research is, naturally, moving to the THz range. Many scientists regard THz as the last great frontier of the electromagnetic spectrum, but finding new applications outside the traditional niches of radio astronomy, Earth and planetary remote sensing, and molecular spectroscopy particularly in biomedical imaging and wireless communications has been relatively slow. Radiologists find this area of study so attractive because t-rays are non-ionizing, which suggests no harm is done to tissue or DNA. They also offer the possibility of performing spectroscopic measurements over a very wide frequency range, and can even capture signatures from liquids and solids. According to Shannon theory, the broad bandwidth of the THz frequency bands can be used for terabit-per-second (Tb/s) wireless communication systems. This enables several new applications, such as cell phones with 360 degrees autostereoscopic displays, optic-fiber replacement, and wireless Tb/s file transferring. Although THz technology could satisfy the demand for an extremely high data rate, a number of technical challenges need to be overcome before its development. This presentation provides an overview the state-of-the- art in THz wireless communication and the technical challenges for an emerging application in Terabit wireless systems. The main issue for THz wave propagation is the high atmospheric attenuation, which is dominated by water vapor absorption in the THz

  11. GLOBALIZATION, COMMUNICATION, EDUCATION

    Directory of Open Access Journals (Sweden)

    Monica Condruz-Bacescu

    2018-03-01

    Full Text Available The paper focuses on the issues of globalization, communication and education. Globalization has become the fundamental theme of political discourse, through its economic dimension, namely by opening up the economic markets in search of new stability points of contemporary developed capitalism; a phenomenon that has led to the free movement of labor, thus involving the social dimension, the circle being closed with the educational dimension because the individual, regardless of the cultural context in which he/she lives, needs training. The global economy cannot be conceived without international communication, which has become a premise of economic success in recent decades. Such communication on which the economic partnerships and multinational organizations are based presupposes an accurate perception and interpretation of the different cultures other than those in which the economic activity takes place and a permanent negotiation of the symbols and reference systems. Education undoubtedly plays an important role in any attempt to address communication networks in these moments of explosive development, networks that mediate communication between people and can thereby help to bring them closer together. Education must directly follow the transformations and new requirements in order to support future changes and professional training. In this direction, education will have as an educational purpose the development of the consciousness of the links between the different components and participants, regardless of the geographic area in which they operate, and on this basis the building of the partnership. Education needs to efficiently and extensively convey that knowledge and information adapted to the new civilization of globalization that does not overwhelm but contribute to the development of people at individual and community level. It must also trace the transformations of the new world that is constantly moving, and at the same time

  12. The sciences of science communication.

    Science.gov (United States)

    Fischhoff, Baruch

    2013-08-20

    The May 2012 Sackler Colloquium on "The Science of Science Communication" brought together scientists with research to communicate and scientists whose research could facilitate that communication. The latter include decision scientists who can identify the scientific results that an audience needs to know, from among all of the scientific results that it would be nice to know; behavioral scientists who can design ways to convey those results and then evaluate the success of those attempts; and social scientists who can create the channels needed for trustworthy communications. This overview offers an introduction to these communication sciences and their roles in science-based communication programs.

  13. Advanced Management Communication: An Elective Course in Corporate Communication.

    Science.gov (United States)

    Argenti, Paul A.

    1986-01-01

    Proposes a college-level elective course in advanced management communication that would teach future managers how to communicate with shareholders, the media, financial analysts, and the labor force. (SRT)

  14. Crisis Communication (Handbooks of Communication Science Vol. 23)

    DEFF Research Database (Denmark)

    Johansen, Winni

    Vol. 23 - The Handbook of Communication Science General editors: Peter J. Schultz and Paul Cobley......Vol. 23 - The Handbook of Communication Science General editors: Peter J. Schultz and Paul Cobley...

  15. Informatics, Culture and Communication in three aspects-communication styles

    Institute of Scientific and Technical Information of China (English)

    WANG Jing; WANG Yun

    2013-01-01

    With the development of business among China, Indian and Australia, people pay more attention to communication chan⁃nels and cross-cultural business ethics and methods as well as cultural, religious and dietary issues that may impact on successful communication. This article talks about cross communication awareness and methods for improving cross cultural communication based on author’s working experience in a firm in Sydney (Australia) that exports foodstuffs to a number of countries in Asia.

  16. Extracellular vesicle communication pathways as regulatory targets of oncogenic transformation.

    Science.gov (United States)

    Choi, Dongsic; Lee, Tae Hoon; Spinelli, Cristiana; Chennakrishnaiah, Shilpa; D'Asti, Esterina; Rak, Janusz

    2017-07-01

    Pathogenesis of human cancers bridges intracellular oncogenic driver events and their impact on intercellular communication. Among multiple mediators of this 'pathological connectivity' the role of extracellular vesicles (EVs) and their subsets (exosomes, ectosomes, oncosomes) is of particular interest for several reasons. The release of EVs from cancer cells represents a unique mechanism of regulated expulsion of bioactive molecules, a process that also mediates cell-to-cell transfer of lipids, proteins, and nucleic acids. Biological effects of these processes have been implicated in several aspects of cancer-related pathology, including tumour growth, invasion, angiogenesis, metastasis, immunity and thrombosis. Notably, the emerging evidence suggests that oncogenic mutations may impact several aspects of EV-mediated cell-cell communication including: (i) EV release rate and protein content; (ii) molecular composition of cancer EVs; (iii) the inclusion of oncogenic and mutant macromolecules in the EV cargo; (iv) EV-mediated release of genomic DNA; (v) deregulation of mechanisms responsible for EV biogenesis (vesiculome) and (vi) mechanisms of EV uptake by cancer cells. Intriguingly, EV-mediated intercellular transfer of mutant and oncogenic molecules between subpopulations of cancer cells, their indolent counterparts and stroma may exert profound biological effects that often resemble (but are not tantamount to) oncogenic transformation, including changes in cell growth, clonogenicity and angiogenic phenotype, or cause cell stress and death. However, several biological barriers likely curtail a permanent horizontal transformation of normal cells through EV-mediated mechanisms. The ongoing analysis and targeting of EV-mediated intercellular communication pathways can be viewed as a new therapeutic paradigm in cancer, while the analysis of oncogenic cargo contained in EVs released from cancer cells into biofluids is being developed for clinical use as a biomarker

  17. Business Communication Students' Appraisal of Selected Communication Competencies

    Science.gov (United States)

    English, Donald E.; Manton, Edgar J.; Walker, Janet I.

    2008-01-01

    The purpose of this study was to determine business communication students' perception of selected business communication competencies. Students enrolled in business communication classes at Texas A&M University-Commerce from the summer of 2006 until the spring 2007 were survey. Students were asked to evaluate each of the listed 44…

  18. Cross-Cultural Communication Patterns in Computer Mediated Communication

    Science.gov (United States)

    Panina, Daria; Kroumova, Maya

    2015-01-01

    There are important cultural differences in attitudes towards and use of electronic text communication. Consistent with Hall's high-context/low-context conceptualization of culture, electronic inter-cultural communication, just as verbal inter-cultural communication, is affected by the culturally-specific assumptions and preferences of message…

  19. Communicative Gestures Facilitate Problem Solving for Both Communicators and Recipients

    Science.gov (United States)

    Lozano, Sandra C.; Tversky, Barbara

    2006-01-01

    Gestures are a common, integral part of communication. Here, we investigate the roles of gesture and speech in explanations, both for communicators and recipients. Communicators explained how to assemble a simple object, using either speech with gestures or gestures alone. Gestures used for explaining included pointing and exhibiting to indicate…

  20. Resonant communicators, effective communicators. Communicator’s flow and credibility

    Directory of Open Access Journals (Sweden)

    Irene García-Ureta, Ph.D

    2012-01-01

    Full Text Available Communication studies have been integrating the latest developments in cognitive sciences and acknowledging the importance of understanding the subjective processes involved in communication. This article argues that communication studies should also take into account the psychology of the communicator. This article presents the theoretical basis and the results of a training programme designed for audiovisual communicators. The programme is based on the theories of self-efficacy and flow and seeks to improve students’ communication competencies through the use of presentation techniques and psychological skills to tackle communication apprehension. The programme involves an active methodology that is based on modelling, visualisation, immediate feedback and positive reinforcement. A repeated-measures ANOVA shows that the programme successfully decreases the level of communication apprehension, improves the perceived self-efficacy, improves the psychological state needed to perform better in front of the cameras (flow, and improves students’ communication skills. A path analysis proved that the perceived self-efficacy and anxiety levels predict the level of flow during the communication act. At the end of the training programme, those who experienced higher levels of flow and enjoyment during the communication task achieved higher quality levels in their communication exercise. It is concluded that the concepts of self-efficacy and flow facilitate advancing in the understanding of the factors that determine a communicator’s credibility and ability to connect with the audience.