WorldWideScience

Sample records for changing transmission settings

  1. Transmission, Acquisition, Parameter-Setting, Reanalysis, and Language Change

    Science.gov (United States)

    Mufwene, Salikoko S.

    2011-01-01

    Jurgen Meisel's (JM) article is literally thought-provoking, especially for the issues that one can raise out of the central position that he develops, viz., "although bilingual acquisition in situations of language contact can be argued to be of significant importance for explanations of grammatical change, reanalysis affecting parameter settings…

  2. The changing epidemiology of measles in an era of elimination: lessons from health-care-setting transmissions of measles during an outbreak in New South Wales, Australia, 2012

    Directory of Open Access Journals (Sweden)

    Alexis Pillsbury

    2016-10-01

    Full Text Available Introduction: In countries where measles is rare, health-care-setting transmissions remain problematic. Australia experienced its largest measles outbreak in 15 years in 2012 with 199 cases reported nationally; 170 cases occurred in the state of New South Wales (NSW with symptom onset between 7 April and 29 November 2012. Methods: A descriptive study was conducted using measles case data obtained from metropolitan Sydney local health districts in NSW in 2012. Characteristics of measles source and secondary cases were described. Details of health-care presentations resulting and not resulting in measles transmission were also analysed. Results: There were 168 confirmed and two probable cases resulting in 405 documented health-care presentations. Thirty-four secondary cases acquired in health-care settings were identified, including 29 cases resulting from 14 source cases and 5 cases whose source could not be identified. Health-care-acquired cases accounted for 20% of all cases in this outbreak. Source cases were more likely to be of Pacific Islander descent (p = 0.009 and to have had more presentations before diagnosis (p = 0.012 compared to other cases. The percentage of presentations to emergency departments was higher for presentations that resulted in transmission compared to those that did not (71.4% and 37.6%, respectively, p = 0.028. There were no significant differences between transmission and non-transmission presentations with respect to presence of rash and infection control measures (p = 0.762 and p = 0.221, respectively, although the power to detect these differences was limited. Rash was reported at 66% of the presentations. Conclusion: Development of and adherence to protocols for the management of patients presenting to hospitals with fever and rash will minimize secondary transmission of measles.

  3. Dynamic Experimental Research on Setting Signal Transmission of Induction Setting System in Muzzle

    Institute of Scientific and Technical Information of China (English)

    HUANG Xue-gong

    2009-01-01

    Muzzle induction setting is a high speed dynamic process. Based on analyzing the process of the projectile flying through an induction setting field, an experimental method is studied to test the effect of high speed plasma gas and high speed projectile on the induction setting system. Three tests are designed. The real-time coupling curves of induction setting signal are tested by coupling a test coil. The experimental results indicate that the electromagnetic field formed by high speed plasma gas can influence the signal transmission of induction setting system, and the influence can be reduced by opening some vents on muzzle; the high speed projectile changed the distributing characteristics of electromagnetic field in the induction setting field to reduce the amplitude of induction coupling signal.

  4. Enterprise Projects Set Risk Element Transmission Chaotic Genetic Model

    Directory of Open Access Journals (Sweden)

    Cunbin Li

    2012-08-01

    Full Text Available In order to research projects set risk transfer process and improve risk management efficiency in projects management, combining chaos theory and genetic algorithm, put forward enterprise projects set risk element transmission chaos genetic model. Using logistic chaos mapping and chebyshev chaos mapping mixture, constructed a hybrid chaotic mapping system. The steps of adopting hybrid chaos mapping for genetic operation include projects set initialization, calculation of fitness, selection, crossover and mutation operators, fitness adjustment and condition judgment. The results showed that the model can simulate enterprise projects set risk transmission process very well and it also provides the basis for the enterprise managers to make decisions.

  5. Quantifying Transmission of Clostridium difficile within and outside Healthcare Settings.

    Science.gov (United States)

    Durham, David P; Olsen, Margaret A; Dubberke, Erik R; Galvani, Alison P; Townsend, Jeffrey P

    2016-04-01

    To quantify the effect of hospital and community-based transmission and control measures on Clostridium difficile infection (CDI), we constructed a transmission model within and between hospital, community, and long-term care-facility settings. By parameterizing the model from national databases and calibrating it to C. difficile prevalence and CDI incidence, we found that hospitalized patients with CDI transmit C. difficile at a rate 15 (95% CI 7.2-32) times that of asymptomatic patients. Long-term care facility residents transmit at a rate of 27% (95% CI 13%-51%) that of hospitalized patients, and persons in the community at a rate of 0.1% (95% CI 0.062%-0.2%) that of hospitalized patients. Despite lower transmission rates for asymptomatic carriers and community sources, these transmission routes have a substantial effect on hospital-onset CDI because of the larger reservoir of hospitalized carriers and persons in the community. Asymptomatic carriers and community sources should be accounted for when designing and evaluating control interventions.

  6. On some transmission problems set in a biological cell, analysis and resolution

    Science.gov (United States)

    Labbas, Rabah; Lemrabet, Keddour; Limam, Kheira; Medeghri, Ahmed; Meisner, Maëlis

    2015-10-01

    Some transmission problems are set in bodies with a crown of small thickness ε > 0. For instance, those concerning the conductivity in the biological cell. By a natural change of variables, we transform them in transmission problems set in two cylindrical bodies ] - ∞, 0 [ × ] - π, π [ and ] 0, δ [ × ] - π, π [ (where δ = ln ⁡ (1 + ε)) and then, in some general elliptic abstract differential equations (Pδ) δ > 0. The goal of this work is to give a complete study of these problems (Pδ) δ > 0 for every δ > 0. Existence, uniqueness and maximal regularity results are obtained for the classical solutions essentially by using the semigroups theory.

  7. Confidence Sets for a Change-Point.

    Science.gov (United States)

    1986-10-01

    probability credible set for j. In fact, even without the explicit evaluation in (1), one knows from a general theorem of Stein (1965) and Hora and...confidence sets with smallest expected measure, Ann. Statist. , 10, 1283-94. Hora , R. B. and Buehler, R. J. (1966), Fiducial theory and invariant...simple cumulative sum type statistic for the change-point problem -’-"C with zero -one observations, Biometrika 67, 79-84. Raferty, A. E. and Akman, V

  8. Framing climate change in a popularised setting:

    DEFF Research Database (Denmark)

    Laursen, Anne Lise; Rasmussen, Kirsten Wølch; Engberg, Jan

    Framing climate change in a popularised setting: The case of the COP conferences The major project from which this presentation has emerged intends to analyze the media communication in connection with mainly the COP15 conference in Copenhagen on climate change 2009 in a number of European...... of the conference. In our part of the project, we look at how knowledge is created via the choice of metaphors. On the basis of an analysis of the framing of the COP15 conference and its goals as presented in the introductory statements by the two Danish presidents of the conference we have found a range of salient...... and with the introductory statement by the president of the Cancún conference in 2010 in order to assess possible influences in the framing from the national and the political setting....

  9. 46 CFR 154.1846 - Relief valves: Changing set pressure.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Relief valves: Changing set pressure. 154.1846 Section... Relief valves: Changing set pressure. The master shall: (a) Supervise the changing of the set pressure of relief valves under § 154.802(b); (b) Enter the change of set pressure in the vessel's log; and...

  10. Socio-Demographics and the Development of Malaria Elimination Strategies in the Low Transmission Setting

    Science.gov (United States)

    Chuquiyauri, Raul; Paredes, Maribel; Peñataro, Pablo; Torres, Sonia; Marin, Silvia; Tenorio, Alexander; Brouwer, Kimberly C.; Abeles, Shira; Llanos-Cuentas, Alejandro; Gilman, Robert H.; Kosek, Margaret; Vinetz, Joseph M.

    2011-01-01

    This analysis presents a comprehensive description of malaria burden and risk factors in Peruvian Amazon villages where malaria transmission is hypoendemic. More than 9,000 subjects were studied in contrasting village settings within the Department of Loreto, Peru, where most malaria occurs in the country. Plasmodium vivax is responsible for more than 75% of malaria cases; severe disease from any form of malaria is uncommon and death rare. The association between lifetime malaria episodes and individual and household covariates was studied using polychotomous logistic regression analysis, assessing effects on odds of some vs. no lifetime malaria episodes. Malaria morbidity during lifetime was strongly associated with age, logging, farming, travel history, and living with a logger or agriculturist. Select groups of adults, particularly loggers and agriculturists acquire multiple malaria infections in transmission settings outside of the main domicile, and may be mobile human reservoirs by which malaria parasites move within and between micro-regions within malaria endemic settings. For example, such individuals might well be reservoirs of transmission by introducing or reintroducing malaria into their home villages and their own households, depending on vector ecology and the local village setting. Therefore, socio-demographic studies can identify people with the epidemiological characteristic of transmission risk, and these individuals would be prime targets against which to deploy transmission blocking strategies along with insecticide treated bednets and chemoprophylaxis. PMID:22100446

  11. Socio-demographics and the development of malaria elimination strategies in the low transmission setting.

    Science.gov (United States)

    Chuquiyauri, Raul; Paredes, Maribel; Peñataro, Pablo; Torres, Sonia; Marin, Silvia; Tenorio, Alexander; Brouwer, Kimberly C; Abeles, Shira; Llanos-Cuentas, Alejandro; Gilman, Robert H; Kosek, Margaret; Vinetz, Joseph M

    2012-03-01

    This analysis presents a comprehensive description of malaria burden and risk factors in Peruvian Amazon villages where malaria transmission is hypoendemic. More than 9000 subjects were studied in contrasting village settings within the Department of Loreto, Peru, where most malaria occurs in the country. Plasmodium vivax is responsible for more than 75% of malaria cases; severe disease from any form of malaria is uncommon and death rare. The association between lifetime malaria episodes and individual and household covariates was studied using polychotomous logistic regression analysis, assessing effects on odds of some vs. no lifetime malaria episodes. Malaria morbidity during lifetime was strongly associated with age, logging, farming, travel history, and living with a logger or agriculturist. Select groups of adults, particularly loggers and agriculturists acquire multiple malaria infections in transmission settings outside of the main domicile, and may be mobile human reservoirs by which malaria parasites move within and between micro-regions within malaria endemic settings. For example, such individuals might well be reservoirs of transmission by introducing or reintroducing malaria into their home villages and their own households, depending on vector ecology and the local village setting. Therefore, socio-demographic studies can identify people with the epidemiological characteristic of transmission risk, and these individuals would be prime targets against which to deploy transmission blocking strategies along with insecticide treated bednets and chemoprophylaxis.

  12. Goal setting as a strategy for health behavior change.

    Science.gov (United States)

    Strecher, V J; Seijts, G H; Kok, G J; Latham, G P; Glasgow, R; DeVellis, B; Meertens, R M; Bulger, D W

    1995-05-01

    This article discusses the beneficial effects of setting goals in health behavior change and maintenance interventions. Goal setting theory predicts that, under certain conditions, setting specific difficult goals leads to higher performance when compared with no goals or vague, nonquantitative goals, such as "do your best." In contrast to the graduated, easy goals often set in health behavior change programs, goal setting theory asserts a positive linear relationship between degree of goal difficulty and level of performance. Research on goal setting has typically been conducted in organizational and laboratory settings. Although goal setting procedures are used in many health behavior change programs, they rarely have been the focus of systematic research. Therefore, many research questions still need to be answered regarding goal setting in the context of health behavior change. Finally, initial recommendations for the successful integration of goal setting theory in health behavior change programs are offered.

  13. Assessing temporal associations between environmental factors and malaria morbidity at varying transmission settings in Uganda

    Directory of Open Access Journals (Sweden)

    Ruth Kigozi

    2016-10-01

    Full Text Available Abstract Background Environmental factors play a major role in transmission of malaria given their relationship to both the development and survival of the mosquito and parasite. The associations between environmental factors and malaria can be used to inform the development of early warning systems for increases in malaria burden. The objective of this study was to assess temporal relationships between rainfall, temperature and vegetation with malaria morbidity across three different transmission settings in Uganda. Methods Temporal relationships between environmental factors (weekly total rainfall, mean day time temperature and enhanced vegetation index series and malaria morbidity (weekly malaria case count data and test positivity rate series over the period January 2010–May 2013 in three sites located in varying malaria transmission settings in Uganda was explored using cross-correlation with pre-whitening. Sites included Kamwezi (low transmission, Kasambya (moderate transmission and Nagongera (high transmission. Results Nagongera received the most rain (30.6 mm and experienced, on average, the highest daytime temperatures (29.8 °C per week. In the study period, weekly TPR and number of malaria cases were highest at Kasambya and lowest at Kamwezi. The largest cross-correlation coefficients between environmental factors and malaria morbidity for each site was 0.27 for Kamwezi (rainfall and cases, 0.21 for Kasambya (vegetation and TPR, and −0.27 for Nagongera (daytime temperature and TPR. Temporal associations between environmental factors (rainfall, temperature and vegetation with malaria morbidity (number of malaria cases and TPR varied by transmission setting. Longer time lags were observed at Kamwezi and Kasambya compared to Nagongera in the relationship between rainfall and number of malaria cases. Comparable time lags were observed at Kasambya and Nagongera in the relationship between temperature and malaria morbidity. Temporal

  14. Influenza transmission during extreme indoor conditions in a low-resource tropical setting

    Science.gov (United States)

    Tamerius, James; Ojeda, Sergio; Uejio, Christopher K.; Shaman, Jeffrey; Lopez, Brenda; Sanchez, Nery; Gordon, Aubree

    2016-08-01

    Influenza transmission occurs throughout the planet across wide-ranging environmental conditions. However, our understanding of the environmental factors mediating transmission is evaluated using outdoor environmental measurements, which may not be representative of the indoor conditions where influenza is transmitted. In this study, we examined the relationship between indoor environment and influenza transmission in a low-resource tropical population. We used a case-based ascertainment design to enroll 34 households with a suspected influenza case and then monitored households for influenza, while recording indoor temperature and humidity data in each household. We show that the indoor environment is not commensurate with outdoor conditions and that the relationship between indoor and outdoor conditions varies significantly across homes. We also show evidence of influenza transmission in extreme indoor environments. Specifically, our data suggests that indoor environments averaged 29 °C, 18 g/kg specific humidity, and 68 % relative humidity across 15 transmission events observed. These indoor settings also exhibited significant temporal variability with temperatures as high as 39 °C and specific and relative humidity increasing to 22 g/kg and 85 %, respectively, during some transmission events. However, we were unable to detect differences in the transmission efficiency by indoor temperature or humidity conditions. Overall, these results indicate that laboratory studies investigating influenza transmission and virus survival should increase the range of environmental conditions that they assess and that observational studies investigating the relationship between environment and influenza activity should use caution using outdoor environmental measurements since they can be imprecise estimates of the conditions that mediate transmission indoors.

  15. CASA Forest Cover Change Data Sets

    Science.gov (United States)

    Potter, Christopher S.

    2012-01-01

    Deforestation and forest fires are global land cover changes that can be caused by both natural and human factors. Although monitoring forest fires in near-real time is critical for operational wildfire management, mapping historical wildfires in a spatially explicit fashion is also important for a number of reasons, including climate change studies (e.g., examining the relationship between rising temperatures and frequency of fires), fuel load management (e.g., deciding when and where to conduct controlled burns), and carbon cycle studies (e.g., quantifying how much CO2 is emitted by fires and for emissions reduction efforts under the United Nations programs for Reducing Emissions from Deforestation and Degradation -- REDD).

  16. Global change, parasite transmission and disease control: lessons from ecology

    Science.gov (United States)

    Boag, Brian; Ellison, Amy R.; Morgan, Eric R.; Murray, Kris; Pascoe, Emily L.; Sait, Steven M.; Booth, Mark

    2017-01-01

    Parasitic infections are ubiquitous in wildlife, livestock and human populations, and healthy ecosystems are often parasite rich. Yet, their negative impacts can be extreme. Understanding how both anticipated and cryptic changes in a system might affect parasite transmission at an individual, local and global level is critical for sustainable control in humans and livestock. Here we highlight and synthesize evidence regarding potential effects of ‘system changes’ (both climatic and anthropogenic) on parasite transmission from wild host–parasite systems. Such information could inform more efficient and sustainable parasite control programmes in domestic animals or humans. Many examples from diverse terrestrial and aquatic natural systems show how abiotic and biotic factors affected by system changes can interact additively, multiplicatively or antagonistically to influence parasite transmission, including through altered habitat structure, biodiversity, host demographics and evolution. Despite this, few studies of managed systems explicitly consider these higher-order interactions, or the subsequent effects of parasite evolution, which can conceal or exaggerate measured impacts of control actions. We call for a more integrated approach to investigating transmission dynamics, which recognizes these complexities and makes use of new technologies for data capture and monitoring, and to support robust predictions of altered parasite dynamics in a rapidly changing world. This article is part of the themed issue ‘Opening the black box: re-examining the ecology and evolution of parasite transmission’. PMID:28289256

  17. Repetition priming-induced changes in sensorimotor transmission.

    Science.gov (United States)

    Svensson, Erik; Evans, Colin G; Cropper, Elizabeth C

    2016-03-01

    When a behavior is repeated performance often improves, i.e., repetition priming occurs. Although repetition priming is ubiquitous, mediating mechanisms are poorly understood. We address this issue in the feeding network ofAplysia Similar to the priming observed elsewhere, priming inAplysiais stimulus specific, i.e., it can be either "ingestive" or "egestive." Previous studies demonstrated that priming alters motor and premotor activity. Here we sought to determine whether sensorimotor transmission is also modified. We report that changes in sensorimotor transmission do occur. We ask how they are mediated and obtain data that strongly suggest a presynaptic mechanism that involves changes in the "background" intracellular Ca(2+)concentration ([Ca(2+)]i) in primary afferents themselves. This form of plasticity has previously been described and generated interest due to its potentially graded nature. Manipulations that alter the magnitude of the [Ca(2+)]iimpact the efficacy of synaptic transmission. It is, however, unclear how graded control is exerted under physiologically relevant conditions. In the feeding system changes in the background [Ca(2+)]iare mediated by the induction of a nifedipine-sensitive current. We demonstrate that the extent to which this current is induced is altered by peptides (i.e., increased by a peptide released during the repetition priming of ingestive activity and decreased by a peptide released during the repetition priming of egestive activity). We suggest that this constitutes a behaviorally relevant mechanism for the graded control of synaptic transmission via the regulation of the [Ca(2+)]iin a neuron.

  18. Comparative population structure of Plasmodium malariae and Plasmodium falciparum under different transmission settings in Malawi

    Directory of Open Access Journals (Sweden)

    Molyneux Malcolm E

    2011-02-01

    Full Text Available Abstract Background Described here is the first population genetic study of Plasmodium malariae, the causative agent of quartan malaria. Although not as deadly as Plasmodium falciparum, P. malariae is more common than previously thought, and is frequently in sympatry and co-infection with P. falciparum, making its study increasingly important. This study compares the population parameters of the two species in two districts of Malawi with different malaria transmission patterns - one seasonal, one perennial - to explore the effects of transmission on population structures. Methods Six species-specific microsatellite markers were used to analyse 257 P. malariae samples and 257 P. falciparum samples matched for age, gender and village of residence. Allele sizes were scored to within 2 bp for each locus and haplotypes were constructed from dominant alleles in multiple infections. Analysis of multiplicity of infection (MOI, population differentiation, clustering of haplotypes and linkage disequilibrium was performed for both species. Regression analyses were used to determine association of MOI measurements with clinical malaria parameters. Results Multiple-genotype infections within each species were common in both districts, accounting for 86.0% of P. falciparum and 73.2% of P. malariae infections and did not differ significantly with transmission setting. Mean MOI of P. falciparum was increased under perennial transmission compared with seasonal (3.14 vs 2.59, p = 0.008 and was greater in children compared with adults. In contrast, P. malariae mean MOI was similar between transmission settings (2.12 vs 2.11 and there was no difference between children and adults. Population differentiation showed no significant differences between villages or districts for either species. There was no evidence of geographical clustering of haplotypes. Linkage disequilibrium amongst loci was found only for P. falciparum samples from the seasonal transmission

  19. Research and Development of Engine-Generator Set Control System for Tracked Vehicle Electric Transmission System

    Institute of Scientific and Technical Information of China (English)

    HUANG Ying; HUANG Qian; SUN Feng-chun; LIU Bo-lan; LIU Jia

    2007-01-01

    As an energy generating equipment, the engine-generator set supplies power to the electric transmission. Therefore, its control is one of the key technologies of electric vehicles. Based on the discussion about the demands to the engine-generator set in tracked vehicles, the detailed function of engine-generator and the control strategy are determined. The hardware and software of the control system are also developed and tested in a prototype vehicle. The experiment results show that the control system has good reliability and can satisfy the power requirements of vehicles under all operating conditions.

  20. The optimisation of the fast neutron and gamma-ray transmission set-up for moisture measurement of coke.

    Science.gov (United States)

    Cywicka-Jakiel, T; Łoskiewicz, J; Tracz, G

    2003-01-01

    In the present paper, modelling calculations with the Monte Carlo (MCNP4C) code were performed for the optimisation of the fast neutron and gamma-ray transmission, set-up, used for the humidity measurement of coke. The optimisation focused on maximising the sensitivity of the neutron flux to humidity changes and on lowering neutron-counting error, both leading to higher accuracy of coke moisture determination. Different materials used for the source shielding and neutron collimation, together with different dimensions of the neutron collimators were studied. The results obtained from the Monte Carlo modelling correlate with the real instrument performance.

  1. Changing dietary habits in a changing world: emerging drivers for the transmission of foodborne parasitic zoonoses.

    Science.gov (United States)

    Broglia, A; Kapel, C

    2011-11-24

    Changing eating habits, population growth and movements, global trade of foodstuff, changes in food production systems, climate change, increased awareness and better diagnostic tools are some of the main drivers affecting the emergence or re-emergence of many foodborne parasitic diseases in recent years. In particular, the increasing demand for exotic and raw food is one of the reasons why reports of foodborne infections, and especially waterborne parasitosis, have increased in the last years. Moreover increasing global demand for protein of animal origin has led to certain farming practices (e.g. aquaculture) increasing in emerging or developing countries, where health monitoring may not be sufficiently implemented. Therefore, high quality epidemiological data are needed which together with biological, economic, social and cultural variables should be taken into account when setting control programs for these increasingly popular production systems in emerging economies. This review focuses on the dietary, social, economic and environmental changes that may cause an increase in human exposure to foodborne parasites. Some examples illustrating these new epidemiological dynamics of transmission foodborne parasitic disease are presented.

  2. Variation transmission model for setting acceptance criteria in a multi-staged pharmaceutical manufacturing process.

    Science.gov (United States)

    Montes, Richard O

    2012-03-01

    Pharmaceutical manufacturing processes consist of a series of stages (e.g., reaction, workup, isolation) to generate the active pharmaceutical ingredient (API). Outputs at intermediate stages (in-process control) and API need to be controlled within acceptance criteria to assure final drug product quality. In this paper, two methods based on tolerance interval to derive such acceptance criteria will be evaluated. The first method is serial worst case (SWC), an industry risk minimization strategy, wherein input materials and process parameters of a stage are fixed at their worst-case settings to calculate the maximum level expected from the stage. This maximum output then becomes input to the next stage wherein process parameters are again fixed at worst-case setting. The procedure is serially repeated throughout the process until the final stage. The calculated limits using SWC can be artificially high and may not reflect the actual process performance. The second method is the variation transmission (VT) using autoregressive model, wherein variation transmitted up to a stage is estimated by accounting for the recursive structure of the errors at each stage. Computer simulations at varying extent of variation transmission and process stage variability are performed. For the scenarios tested, VT method is demonstrated to better maintain the simulated confidence level and more precisely estimate the true proportion parameter than SWC. Real data examples are also presented that corroborate the findings from the simulation. Overall, VT is recommended for setting acceptance criteria in a multi-staged pharmaceutical manufacturing process.

  3. Using goal setting as a strategy for dietary behavior change.

    Science.gov (United States)

    Cullen, K W; Baranowski, T; Smith, S P

    2001-05-01

    Recent reviews have noted that behavioral theory-based nutrition education programs are more successful at achieving food behavior change than knowledge-based programs and that a clear understanding of the mechanisms of behavior change procedures enable dietetics professionals to more effectively promote change. Successful dietary behavior change programs target 1 or more of the personal, behavioral, or environmental factors that influence the behavior of interest and apply theory-based strategies to influence or change those factors. Goal setting is a strategy that is frequently used to help people change. A 4-step goal-setting process has been identified: recognizing a need for change; establishing a goal; adopting a goal-directed activity and self-monitoring it; and self-rewarding goal attainment. The applications of goal setting in dietary interventions for adults and children are reviewed here. Because interventions using goal setting appear to promote dietary change, dietitians should consider incorporating the goal-setting strategies to enhance the behavior change process in nutrition education programs.

  4. Detecting a trend change in cross-border epidemic transmission

    Science.gov (United States)

    Maeno, Yoshiharu

    2016-09-01

    A method for a system of Langevin equations is developed for detecting a trend change in cross-border epidemic transmission. The equations represent a standard epidemiological SIR compartment model and a meta-population network model. The method analyzes a time series of the number of new cases reported in multiple geographical regions. The method is applicable to investigating the efficacy of the implemented public health intervention in managing infectious travelers across borders. It is found that the change point of the probability of travel movements was one week after the WHO worldwide alert on the SARS outbreak in 2003. The alert was effective in managing infectious travelers. On the other hand, it is found that the probability of travel movements did not change at all for the flu pandemic in 2009. The pandemic did not affect potential travelers despite the WHO alert.

  5. Informative conditions for the data set in an MIMO networked control system with delays, packet dropout and transmission scheduling

    Science.gov (United States)

    Zhang, Cong; Xiong, Zhihua; Ye, Hao

    2014-07-01

    In system identification, a data set needs to be informative to guarantee that the identification criterion has a unique global minimum asymptotically and the parameter estimation is consistent. In this paper, we study the informativity of the data set in a multiple-input and multiple-output (MIMO) networked control system (NCS), which contains possible network-induced delays, packet dropout, transmission scheduling, or a combination of these factors in network transmission. Moreover, to guarantee the data set of this MIMO NCS to be informative, a group of conditions for network transmission and controller's proportional term are developed. Finally, simulation studies are given to illustrate the result.

  6. Indirect Transmission of Influenza A Virus between Pig Populations under Two Different Biosecurity Settings.

    Directory of Open Access Journals (Sweden)

    Matt W Allerson

    Full Text Available Respiratory disease due to influenza virus is common in both human and swine populations around the world with multiple transmission routes capable of transmitting influenza virus, including indirect routes. The objective of this study was to evaluate the role of fomites in influenza A virus (IAV transmission between pig populations separated by two different biosecurity settings. Thirty-five pigs were divided into four experimental groups: 10 pigs (1 replicate were assigned to the infected group (I, 10 pigs (2 replicates of 5 pigs were assigned to the low biosecurity sentinel group (LB, 10 pigs (2 replicates of 5 pigs were assigned to the medium biosecurity sentinel group (MB, and 5 pigs (1 replicate were assigned to the negative control group (NC. Eight of 10 pigs in the infected group were inoculated with IAV and 36 hours following inoculation, personnel movement events took place in order to move potentially infectious clothing and personal protective equipment (PPE to sentinel pig rooms. Following contact with the infected group, personnel moved to the MB group after designated hygiene measures while personnel moved directly to the LB group. Nasal swabs and blood samples were collected from pigs to assess IAV infection status and fomites were sampled and tested via RRT-PCR. All experimentally inoculated pigs were infected with IAV and 11 of the 144 fomite samples collected following contact with infected pigs were low level positive for IAV genome. One replicate of each sentinel groups LB and MB became infected with IAV and all five pigs were infected over time. This study provides evidence that fomites can serve as an IAV transmission route from infected to sentinel pigs and highlights the need to focus on indirect routes as well as direct routes of transmission for IAV.

  7. PERSPECTIVE HYDROSTATIC-MECHANICAL TRANSMISSIONS FOR WHEELED TRACTORS OF AGRICULTURAL SETTING

    OpenAIRE

    Samorodov, V.; Bondarenko, A.

    2013-01-01

    The kinematics charts of perspective hydrostatic-mechanical transmission are presented, their basic structural parameters, the size of hydraulic machines of hydrostatic transmission are identified, the kinematic and power parameters of transmissions are determined.

  8. Maternal-foetal transfer of Plasmodium falciparum and Plasmodium vivax antibodies in a low transmission setting

    Science.gov (United States)

    Charnaud, Sarah C.; McGready, Rose; Herten-Crabb, Asha; Powell, Rosanna; Guy, Andrew; Langer, Christine; Richards, Jack S.; Gilson, Paul R.; Chotivanich, Kesinee; Tsuboi, Takafumi; Narum, David L.; Pimanpanarak, Mupawjay; Simpson, Julie A.; Beeson, James G.; Nosten, François; Fowkes, Freya J. I.

    2016-01-01

    During pregnancy immunolglobulin G (IgG) antibodies are transferred from mother to neonate across the placenta. Studies in high transmission areas have shown transfer of P. falciparum-specific IgG, but the extent and factors influencing maternal-foetal transfer in low transmission areas co-endemic for both P. falciparum and P. vivax are unknown. Pregnant women were screened weekly for Plasmodium infection. Mother-neonate paired serum samples at delivery were tested for IgG to antigens from P. falciparum, P. vivax and other infectious diseases. Antibodies to malarial and non-malarial antigens were highly correlated between maternal and neonatal samples (median [range] spearman ρ = 0.78 [0.57–0.93]), although Plasmodium spp. antibodies tended to be lower in neonates than mothers. Estimated gestational age at last P. falciparum infection, but not P. vivax infection, was positively associated with antibody levels in the neonate (P. falciparum merozoite, spearman ρ median [range] 0.42 [0.33–0.66], PfVAR2CSA 0.69; P. vivax ρ = 0.19 [0.09–0.3]). Maternal-foetal transfer of anti-malarial IgG to Plasmodium spp. antigens occurs in low transmission settings. P. vivax IgG acquisition is not associated with recent exposure unlike P. falciparum IgG, suggesting a difference in acquisition of antibodies. IgG transfer is greatest in the final weeks of pregnancy which has implications for the timing of future malaria vaccination strategies in pregnant women. PMID:26861682

  9. Intraspecies Transmission of BASE Induces Clinical Dullness and Amyotrophic Changes

    Science.gov (United States)

    Lombardi, Guerino; Casalone, Cristina; D' Angelo, Antonio; Gelmetti, Daniela; Torcoli, Gloria; Barbieri, Ilaria; Corona, Cristiano; Fasoli, Elisa; Farinazzo, Alessia; Fiorini, Michele; Gelati, Matteo; Iulini, Barbara; Tagliavini, Fabrizio; Ferrari, Sergio; Caramelli, Maria; Monaco, Salvatore; Capucci, Lorenzo; Zanusso, Gianluigi

    2008-01-01

    The disease phenotype of bovine spongiform encephalopathy (BSE) and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in 1986. In recent years, systematic testing of the brains of cattle coming to slaughter resulted in the identification of at least two atypical forms of BSE. These emerging disorders are characterized by novel conformers of the bovine pathological prion protein (PrPTSE), named high-type (BSE-H) and low-type (BSE-L). We recently reported two Italian atypical cases with a PrPTSE type identical to BSE-L, pathologically characterized by PrP amyloid plaques and known as bovine amyloidotic spongiform encephalopathy (BASE). Several lines of evidence suggest that BASE is highly virulent and easily transmissible to a wide host range. Experimental transmission to transgenic mice overexpressing bovine PrP (Tgbov XV) suggested that BASE is caused by a prion strain distinct from the BSE isolate. In the present study, we experimentally infected Friesian and Alpine brown cattle with Italian BSE and BASE isolates via the intracerebral route. BASE-infected cattle developed amyotrophic changes accompanied by mental dullness. The molecular and neuropathological profiles, including PrP deposition pattern, closely matched those observed in the original cases. This study provides clear evidence of BASE as a distinct prion isolate and discloses a novel disease phenotype in cattle. PMID:18497860

  10. Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes.

    Directory of Open Access Journals (Sweden)

    Guerino Lombardi

    2008-05-01

    Full Text Available The disease phenotype of bovine spongiform encephalopathy (BSE and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in 1986. In recent years, systematic testing of the brains of cattle coming to slaughter resulted in the identification of at least two atypical forms of BSE. These emerging disorders are characterized by novel conformers of the bovine pathological prion protein (PrP(TSE, named high-type (BSE-H and low-type (BSE-L. We recently reported two Italian atypical cases with a PrP(TSE type identical to BSE-L, pathologically characterized by PrP amyloid plaques and known as bovine amyloidotic spongiform encephalopathy (BASE. Several lines of evidence suggest that BASE is highly virulent and easily transmissible to a wide host range. Experimental transmission to transgenic mice overexpressing bovine PrP (Tgbov XV suggested that BASE is caused by a prion strain distinct from the BSE isolate. In the present study, we experimentally infected Friesian and Alpine brown cattle with Italian BSE and BASE isolates via the intracerebral route. BASE-infected cattle developed amyotrophic changes accompanied by mental dullness. The molecular and neuropathological profiles, including PrP deposition pattern, closely matched those observed in the original cases. This study provides clear evidence of BASE as a distinct prion isolate and discloses a novel disease phenotype in cattle.

  11. Intraspecies transmission of BASE induces clinical dullness and amyotrophic changes.

    Science.gov (United States)

    Lombardi, Guerino; Casalone, Cristina; D' Angelo, Antonio; Gelmetti, Daniela; Torcoli, Gloria; Barbieri, Ilaria; Corona, Cristiano; Fasoli, Elisa; Farinazzo, Alessia; Fiorini, Michele; Gelati, Matteo; Iulini, Barbara; Tagliavini, Fabrizio; Ferrari, Sergio; Caramelli, Maria; Monaco, Salvatore; Capucci, Lorenzo; Zanusso, Gianluigi

    2008-05-23

    The disease phenotype of bovine spongiform encephalopathy (BSE) and the molecular/ biological properties of its prion strain, including the host range and the characteristics of BSE-related disorders, have been extensively studied since its discovery in 1986. In recent years, systematic testing of the brains of cattle coming to slaughter resulted in the identification of at least two atypical forms of BSE. These emerging disorders are characterized by novel conformers of the bovine pathological prion protein (PrP(TSE)), named high-type (BSE-H) and low-type (BSE-L). We recently reported two Italian atypical cases with a PrP(TSE) type identical to BSE-L, pathologically characterized by PrP amyloid plaques and known as bovine amyloidotic spongiform encephalopathy (BASE). Several lines of evidence suggest that BASE is highly virulent and easily transmissible to a wide host range. Experimental transmission to transgenic mice overexpressing bovine PrP (Tgbov XV) suggested that BASE is caused by a prion strain distinct from the BSE isolate. In the present study, we experimentally infected Friesian and Alpine brown cattle with Italian BSE and BASE isolates via the intracerebral route. BASE-infected cattle developed amyotrophic changes accompanied by mental dullness. The molecular and neuropathological profiles, including PrP deposition pattern, closely matched those observed in the original cases. This study provides clear evidence of BASE as a distinct prion isolate and discloses a novel disease phenotype in cattle.

  12. Developmental changes in the acute ethanol sensitivity of glutamatergic and GABAergic transmission in the BNST.

    Science.gov (United States)

    Wills, T A; Kash, T L; Winder, D G

    2013-11-01

    Glutamatergic and GABAergic transmission undergo significant changes during adolescence. Receptors for both of these transmitters (NMDAR, and GABAA) are known to be key targets for the acute effects of ethanol in adults. The current study set out to investigate the acute effects of ethanol on both NMDAR-mediated excitatory transmission and GABAergic inhibitory transmission within the bed nucleus of the stria terminalis (BNST) across age. The BNST is an area of the brain implicated in the negative reinforcing properties associated with alcohol dependence, and the BNST plays a critical role in stress-induced relapse. Therefore, assessing the developmental regulation of ethanol sensitivity in this key brain region is important to understanding the progression of ethanol dependence. To do this, whole-cell recordings of isolated NMDAR-evoked excitatory postsynaptic currents (eEPSCs) or evoked GABAergic inhibitory postsynaptic currents (eIPSCs) were performed on BNST neurons in slices from 4- or 8-week-old male C57BL/6J mice. Ethanol (50 mm) produced greater inhibition of NMDAR-eEPSCs in adolescent mice than in adult mice. This enhanced sensitivity in adolescence was not a result of shifts in function of the GluN2B subunit of the NMDAR, measured by Ro25-6981 inhibition and decay kinetics measured across age. Adolescent mice also exhibited greater ethanol sensitivity of GABAergic transmission, as ethanol (50 mm) enhanced eIPSCs in the BNST of adolescent but not adult mice. Collectively, this work illustrates that a moderate dose of ethanol produces greater inhibition of transmission in the BNST (through greater excitatory inhibition and enhancement of inhibitory transmission) in adolescents compared to adults. Given the role of the BNST in alcohol dependence, these developmental changes in acute ethanol sensitivity could accelerate neuroadaptations that result from chronic ethanol use during the critical period of adolescence.

  13. Towards a Framework for Change Detection in Data Sets

    Science.gov (United States)

    Böttcher, Mirko; Nauck, Detlef; Ruta, Dymitr; Spott, Martin

    Since the world with its markets, innovations and customers is changing faster than ever before, the key to survival for businesses is the ability to detect, assess and respond to changing conditions rapidly and intelligently. Discovering changes and reacting to or acting upon them before others do has therefore become a strategical issue for many companies. However, existing data analysis techniques are insufflent for this task since they typically assume that the domain under consideration is stable over time. This paper presents a framework that detects changes within a data set at virtually any level of granularity. The underlying idea is to derive a rule-based description of the data set at different points in time and to subsequently analyse how these rules change. Nevertheless, further techniques are required to assist the data analyst in interpreting and assessing their changes. Therefore the framework also contains methods to discard rules that are non-drivers for change and to assess the interestingness of detected changes.

  14. A hybrid particle swarm optimization approach with neural network and set pair analysis for transmission network planning

    Institute of Scientific and Technical Information of China (English)

    刘吉成; 颜苏莉; 乞建勋

    2008-01-01

    Transmission network planning (TNP) is a large-scale, complex, with more non-linear discrete variables and the multi-objective constrained optimization problem. In the optimization process, the line investment, network reliability and the network loss are the main objective of transmission network planning. Combined with set pair analysis (SPA), particle swarm optimization (PSO), neural network (NN), a hybrid particle swarm optimization model was established with neural network and set pair analysis for transmission network planning (HPNS). Firstly, the contact degree of set pair analysis was introduced, the traditional goal set was converted into the collection of the three indicators including the identity degree, difference agree and contrary degree. On this bases, using shi(H), the three objective optimization problem was converted into single objective optimization problem. Secondly, using the fast and efficient search capabilities of PSO, the transmission network planning model based on set pair analysis was optimized. In the process of optimization, by improving the BP neural network constantly training so that the value of the fitness function of PSO becomes smaller in order to obtain the optimization program fitting the three objectives better. Finally, compared HPNS with PSO algorithm and the classic genetic algorithm, HPNS increased about 23% efficiency than THA, raised about 3.7% than PSO and improved about 2.96% than GA.

  15. Influence of contact definitions in assessment of the relative importance of social settings in disease transmission risk.

    Directory of Open Access Journals (Sweden)

    Kirsty J Bolton

    Full Text Available BACKGROUND: Realistic models of disease transmission incorporating complex population heterogeneities require input from quantitative population mixing studies. We use contact diaries to assess the relative importance of social settings in respiratory pathogen spread using three measures of person contact hours (PCH as proxies for transmission risk with an aim to inform bipartite network models of respiratory pathogen transmission. METHODS AND FINDINGS: Our survey examines the contact behaviour for a convenience sample of 65 adults, with each encounter classified as occurring in a work, retail, home, social, travel or "other" setting. The diary design allows for extraction of PCH-interaction (cumulative time in face-face conversational or touch interaction with contacts--analogous to the contact measure used in several existing surveys--as well as PCH-setting (product of time spent in setting and number of people present and PCH-reach (product of time spent in setting and number of people in close proximity. Heterogeneities in day-dependent distribution of risk across settings are analysed using partitioning and cluster analyses and compared between days and contact measures. Although home is typically the highest-risk setting when PCH measures isolate two-way interactions, its relative importance compared to social and work settings may reduce when adopting a more inclusive contact measure that considers the number and duration of potential exposure events. CONCLUSIONS: Heterogeneities in location-dependent contact behaviour as measured by contact diary studies depend on the adopted contact definition. We find that contact measures isolating face-face conversational or touch interactions suggest that contact in the home dominates, whereas more inclusive contact measures indicate that home and work settings may be of higher importance. In the absence of definitive knowledge of the contact required to facilitate transmission of various

  16. Low rates of mother-to-child HIV transmission in a routine programmatic setting in Lilongwe, Malawi.

    Directory of Open Access Journals (Sweden)

    Maria H Kim

    Full Text Available BACKGROUND: The Tingathe program utilizes community health workers to improve prevention of mother-to-child transmission (PMTCT service delivery. We evaluated the impact of antiretroviral (ARV regimen and maternal CD4+ count on HIV transmission within the Tingathe program in Lilongwe, Malawi. METHODS: We reviewed clinical records of 1088 mother-infant pairs enrolled from March 2009 to March 2011 who completed follow-up to first DNA PCR. Eligibility for antiretroviral treatment (ART was determined by CD4+ cell count (CD4+ for women not yet on ART. ART-eligible women initiated stavudine-lamivudine-nevirapine. Early ART was defined as ART for ≥14 weeks prior to delivery. For women ineligible for ART, optimal ARV prophylaxis was maternal AZT ≥6 weeks+sdNVP, and infant sdNVP+AZT for 1 week. HIV transmission rates were determined for ARV regimens, and factors associated with vertical transmission were identified using bivariate logistic regression. RESULTS: Transmission rate at first PCR was 4.1%. Pairs receiving suboptimal ARV prophylaxis were more likely to transmit HIV (10.3%, 95% CI, 5.5-18.1%. ART was associated with reduced transmission (1.4%, 95% CI, 0.6-3.0%, with early ART associated with decreased transmission (no transmission, compared to all other treatment groups (p = 0.001. No association was detected between transmission and CD4+ categories (p = 0.337, trimester of pregnancy at enrollment (p = 0.100, or maternal age (p = 0.164. CONCLUSION: Low rates of MTCT of HIV are possible in resource-constrained settings under routine programmatic conditions. No transmissions were observed among women on ART for more than 14 weeks prior to delivery.

  17. A general approach to belief change in answer set programming

    CERN Document Server

    Delgrande, James; Tompits, Hans; Woltran, Stefan

    2009-01-01

    We address the problem of belief change in (nonmonotonic) logic programming under answer set semantics. Unlike previous approaches to belief change in logic programming, our formal techniques are analogous to those of distance-based belief revision in propositional logic. In developing our results, we build upon the model theory of logic programs furnished by SE models. Since SE models provide a formal, monotonic characterisation of logic programs, we can adapt techniques from the area of belief revision to belief change in logic programs. We introduce methods for revising and merging logic programs, respectively. For the former, we study both subset-based revision as well as cardinality-based revision, and we show that they satisfy the majority of the AGM postulates for revision. For merging, we consider operators following arbitration merging and IC merging, respectively. We also present encodings for computing the revision as well as the merging of logic programs within the same logic programming framework...

  18. Tracing Mycobacterium tuberculosis transmission by whole genome sequencing in a high incidence setting

    DEFF Research Database (Denmark)

    Bjorn-Mortensen, K; Soborg, B; Koch, A;

    2016-01-01

    In East Greenland, a dramatic increase of tuberculosis (TB) incidence has been observed in recent years. Classical genotyping suggests a genetically similar Mycobacterium tuberculosis (Mtb) strain population as cause, however, precise transmission patterns are unclear. We performed whole genome...

  19. Dengue transmission in the small-island setting: investigations from the Caribbean island of Grenada

    DEFF Research Database (Denmark)

    Schiøler, Karin Linda; Macpherson, Calum N

    2009-01-01

    The Caribbean region has experienced a major surge in dengue activity in recent decades. Yet, for many, and especially the smaller islands, the true extent and general epidemiology of dengue transmission remains unclear because of inadequate systems of surveillance and reporting. We established a...... benign dengue fever. A shift in serotype activity and modal age was evident during the noted transition, with the more densely populated south end of the island presenting the focus of transmission....

  20. 78 FR 57372 - Northern Pass Transmission Line Project Environmental Impact Statement: Announcement of Change in...

    Science.gov (United States)

    2013-09-18

    ... Northern Pass Transmission Line Project Environmental Impact Statement: Announcement of Change in Public... amended Notice of Intent (NOI) to modify the scope of the Northern Pass Transmission Line Project... previously announced this change in public meeting location on both the Northern Pass EIS Web site at...

  1. Setting standards for radiation protection: A time for change

    Energy Technology Data Exchange (ETDEWEB)

    Patterson, H.W.; Hickman, D.P.

    1996-01-01

    In 1950, the International Commission on Radiation Protection (ICRP) recommended that ``certain radiation effects are irreversible and cumulative.`` Furthermore, the ICRP ``strongly recommended that every effort be made to reduce exposures to all types of ionizing radiations to the lowest possible level.`` Then in 1954, the ICRP published its assumption that human response to ionizing radiation was linear with dose, together with the recommendation that exposures be kept as low as practicable. These concepts are still the foundation of radiation protection policy today, even though, as Evans has stated, ``The linear non-threshold (LNT) model was adopted specifically on a basis of mathematical simplicity, not from radio-biological data.... Groups responsible for setting standards for radiation protection should be abreast of new developments and new data as they are published; however, this does not seem to be the case. For example, there have been many reports in scientific, peer-reviewed, and other publications during the last three decades that have shown the LNT model and the policy of As Low As Reasonably Achievable (ALARA) to be invalid. However, none of these reports has been refuted or even discussed by standard-setting groups. We believe this mandates a change in the standard-setting process.

  2. Preventing Transmission of Zika Virus in Labor and Delivery Settings Through Implementation of Standard Precautions - United States, 2016.

    Science.gov (United States)

    Olson, Christine K; Iwamoto, Martha; Perkins, Kiran M; Polen, Kara N D; Hageman, Jeffrey; Meaney-Delman, Dana; Igbinosa, Irogue I; Khan, Sumaiya; Honein, Margaret A; Bell, Michael; Rasmussen, Sonja A; Jamieson, Denise J

    2016-03-25

    Zika virus transmission was detected in the Region of the Americas (Americas) in Brazil in May 2015, and as of March 21, 2016, local mosquito-borne transmission of Zika virus had been reported in 32 countries and territories in the Americas, including Puerto Rico and the U.S. Virgin Islands.* Most persons infected with Zika virus have a mild illness or are asymptomatic. However, increasing evidence supports a link between Zika virus infection during pregnancy and adverse pregnancy and birth outcomes (1), and a possible association between recent Zika virus infection and Guillain-Barré syndrome has been reported (2). Although Zika virus is primarily transmitted through the bite of Aedes species of mosquitoes, sexual transmission also has been documented (3). Zika virus RNA has been detected in a number of body fluids, including blood, urine, saliva, and amniotic fluid (3-5), and whereas transmission associated with occupational exposure to these body fluids is theoretically possible, it has not been documented. Although there are no reports of transmission of Zika virus from infected patients to health care personnel or other patients, minimizing exposures to body fluids is important to reduce the possibility of such transmission. CDC recommends Standard Precautions in all health care settings to protect both health care personnel and patients from infection with Zika virus as well as from blood-borne pathogens (e.g., human immunodeficiency virus [HIV] and hepatitis C virus [HCV]) (6). Because of the potential for exposure to large volumes of body fluids during the labor and delivery process and the sometimes unpredictable and fast-paced nature of obstetrical care, the use of Standard Precautions in these settings is essential to prevent possible transmission of Zika virus from patients to health care personnel.

  3. In Situ Transmission Electron Microscopy Observation of Nanostructural Changes in Phase-Change Memory

    KAUST Repository

    Meister, Stefan

    2011-04-26

    Phase-change memory (PCM) has been researched extensively as a promising alternative to flash memory. Important studies have focused on its scalability, switching speed, endurance, and new materials. Still, reliability issues and inconsistent switching in PCM devices motivate the need to further study its fundamental properties. However, many investigations treat PCM cells as black boxes; nanostructural changes inside the devices remain hidden. Here, using in situ transmission electron microscopy, we observe real-time nanostructural changes in lateral Ge2Sb2Te5 (GST) PCM bridges during switching. We find that PCM devices with similar resistances can exhibit distinct threshold switching behaviors due to the different initial distribution of nanocrystalline and amorphous domains, explaining variability of switching behaviors of PCM cells in the literature. Our findings show a direct correlation between nanostructure and switching behavior, providing important guidelines in the design and operation of future PCM devices with improved endurance and lower variability. © 2011 American Chemical Society.

  4. Blood-borne virus transmission in healthcare settings in Ireland: review of patient notification exercises 1997-2011.

    LENUS (Irish Health Repository)

    Donohue, S

    2012-01-21

    A review of patient notification exercises (PNEs) carried out in Ireland between 1997 and 2011 to investigate potential exposure to blood-borne viruses (BBVs) in healthcare settings was undertaken to inform future policy and practice. A questionnaire was sent to key informants in the health services to identify all relevant PNEs. Structured interviews were conducted with key investigators, and available documentation was examined. Ten BBV-related PNEs were identified. Despite testing over 2000 patients, only one case of transmission was found. However, in-depth local investigations before undertaking the PNEs identified six cases of healthcare-associated transmission.

  5. Changes in parasite transmission stage excretion after pheasant release

    OpenAIRE

    2006-01-01

    The production of parasite transmission stages was investigated in the faeces of 77 farm-bred ring-necked pheasants (Phasianus colchicus). Coccidian oocysts (Eimeria sp.), and nematode eggs (Heterakis sp., and Capillaria-like eggs) were recovered before and after release but all birds were treated prior to release. Treatment with fenbendazole significantly reduced the abundance of trans-mission-stage excretion for all parasites, and reduced the prevalence in the case of Eimeria sp. and Hetera...

  6. Changes in parasite transmission stage excretion after pheasant release.

    Science.gov (United States)

    Villanúa, D; Acevedo, P; Höfle, U; Rodríguez, O; Gortázar, C

    2006-09-01

    The production of parasite transmission stages was investigated in the faeces of 77 farm-bred ring-necked pheasants (Phasianus colchicus). Coccidian oocysts (Eimeria sp.), and nematode eggs (Heterakis sp., and Capillaria-like eggs) were recovered before and after release but all birds were treated prior to release. Treatment with fenbendazole significantly reduced the abundance of transmission-stage excretion for all parasites, and reduced the prevalence in the case of Eimeria sp. and Heterakis sp. Nonetheless, a significant increase in the excretion abundance for all parasites and in the prevalence of Eimeria sp. and Heterakis sp. was found after release. Eggs of Ascaridia sp. were found only after releasing, suggesting infection ocurred in the wild. A negative relationship was found between the pheasant body condition and Heterakis excretion abundance and a higher abundance of Capillaria sp. eggs in female birds. No significant relationship was found between parasite excretion abundance and pheasant survival. Despite this, results suggest that an increase in the excretion of parasite transmission stages follows the release of captive pheasants into the wild. This can in part explain restocking failures, but also means that autochtonous free-living birds may become exposed to new and potentially harmful pathogens. To avoid these risks it is proposed that improved prophylactic measures should be taken.

  7. Striving for Sustainable Organizational Changes in Hypercomplex Settings

    DEFF Research Database (Denmark)

    Neisig, Margit

    2017-01-01

    conceptualization of different types of PMS to the levels of re-entry conceptualized in step 2 Findings This allows revealing the interplay of different types of PMS systems and whether they hinder or stabilize this long and vulnerable chain of re-entries needed in the striving for sustainable organizational...... changes in hypercomplex settings. Practical implications Has strategic interest when developing and implementing performance management and measurement systems in both public and private sectors, and contributes to a discussion on, what it means to have adequate measures for success and failure......, and to enable organizational development (OD) to address the big question of the day. Originality/Value: The article adds to organizational development, HRM, NPM and performance management by providing a conception on, what it takes to become reflective of a higher order as to strive towards sustainability...

  8. Investigation of unique hue setting changes with ageing

    Institute of Scientific and Technical Information of China (English)

    Chenyang Fu; Kaida Xiao; Dimosthenis Karatzas; Sophie Wuerger

    2011-01-01

    Clromatic sensitivity along the protan, deutan, and tritan lines and the loci of the unique hues (red, green,yellow, blue) for a very large sample (n = 185) of colour-normal observers ranging from 18 to 75 years of age are assessed. Visual judgments are obtained under normal viewing conditions using colour patches on self-luminous display under controlled adaptation conditions. Trivector discrimination thresholds show an increase as a function of age along the protan, deutan, and tritan axes, with the largest increase present along the tritan line, less pronounced shifts in unique hue settings are also observed. Based on the chromatic (protan, deutan, tritan) thresholds and using scaled cone signals, we predict the unique hue changes with ageing. A dependency on age for unique red and unique yellow for predicted hue angle is found. We conclude that the chromatic sensitivity deteriorates significantly with age, whereas the appearance of unique hues is much less affected, remaining almost constant despite the known changes in the ocular media.%@@ Clromatic sensitivity along the protan, deutan, and tritan lines and the loci of the unique hues (red, green,yellow, blue) for a very large sample (n = 185) of colour-normal observers ranging from 18 to 75 years of age are assessed.Visual judgments are obtained under normal viewing conditions using colour patches on self-luminous display under controlled adaptation conditions.Trivector discrimination thresholds show an increase as a function of age along the protan, deutan, and tritan axes, with the largest increase present along the tritan line, less pronounced shifts in unique hue settings are also observed.

  9. Whole-genome sequencing to detect recent transmission of Mycobacterium tuberculosis in settings with a high burden of tuberculosis.

    Science.gov (United States)

    Luo, Tao; Yang, Chongguang; Peng, Ying; Lu, Liping; Sun, Guomei; Wu, Jie; Jin, Xiaoping; Hong, Jianjun; Li, Fabin; Mei, Jian; DeRiemer, Kathryn; Gao, Qian

    2014-07-01

    Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been used to trace the transmission of M. tuberculosis, the causative agent of tuberculosis (TB). Previously published studies using WGS were conducted in developed countries with a low TB burden. We sought to evaluate the relative usefulness of traditional VNTR and SNP typing methods, WGS and epidemiological investigations to study the recent transmission of M. tuberculosis in a high TB burden country. We conducted epidemiological investigations of 42 TB patients whose M. tuberculosis isolates were classified into three clusters based on variable-number tandem repeat (VNTR) typing. We applied WGS to 32 (76.2%) of the 42 strains and calculated the pairwise genomic distances between strains within each cluster. Eighteen (56.3%) of the 32 strains had genomic differences ≥100 SNPs with every other strain, suggesting that direct transmission did not likely occurred. Ten strains were grouped into four WGS-based clusters with genomic distances ≤5 SNPs within each cluster, and confirmed epidemiological links were identified in two of these clusters. Our results indicate that WGS provides reliable resolution for tracing the transmission of M. tuberculosis in high TB burden settings. The high resolution of WGS is particularly useful to confirm or exclude the possibility of direct transmission events defined by traditional typing methods.

  10. Monkeypox disease transmission in an experimental setting: prairie dog animal model.

    Directory of Open Access Journals (Sweden)

    Christina L Hutson

    Full Text Available Monkeypox virus (MPXV is considered the most significant human public health threat in the genus Orthopoxvirus since the eradication of variola virus (the causative agent of smallpox. MPXV is a zoonotic agent endemic to forested areas of Central and Western Africa. In 2003, MPXV caused an outbreak in the United States due to the importation of infected African rodents, and subsequent sequential infection of North American prairie dogs (Cynomys ludovicianus and humans. In previous studies, the prairie dog MPXV model has successfully shown to be very useful for understanding MPXV since the model emulates key characteristics of human monkeypox disease. In humans, percutaneous exposure to animals has been documented but the primary method of human-to-human MPXV transmission is postulated to be by respiratory route. Only a few animal model studies of MPXV transmission have been reported. Herein, we show that MPXV infected prairie dogs are able to transmit the virus to naive animals through multiple transmission routes. All secondarily exposed animals were infected with MPXV during the course of the study. Notably, animals secondarily exposed appeared to manifest more severe disease; however, the disease course was very similar to those of experimentally challenged animals including inappetence leading to weight loss, development of lesions, production of orthopoxvirus antibodies and shedding of similar levels or in some instances higher levels of MPXV from the oral cavity. Disease was transmitted via exposure to contaminated bedding, co-housing, or respiratory secretions/nasal mucous (we could not definitively say that transmission occurred via respiratory route exclusively. Future use of the model will allow us to evaluate infection control measures, vaccines and antiviral strategies to decrease disease transmission.

  11. Consideration of future climatic changes in three geologic settings

    Energy Technology Data Exchange (ETDEWEB)

    Petrie, G.M.

    1984-09-01

    Staff at Pacific Northwest Laboratory are evaluating the potential for climatic change to affect the integrity of a nuclear waste repository at: (1) the Gibson Dome area of Utah; (2) the Palo Duro Basin of Texas; and (3) the Gulf Coast. Because a major assumption in this analysis is that a glacial age will recur, the climate of the last glacial period is examined for each location. Combining these paleoclimatic data with the current climatic data, each location is evaluated in light of the criteria given in Draft Revised General Guidelines for Recommendation of Sites for Nuclear Waste Repositories (10 CFR 960). The results of this analysis suggest that sites located in these areas are likely to meet the climate requirements set forth in the guidelines. However, further study is needed before a definitive statement can be made. In particular, modeling the effect of sea level change on the Gulf Coast groundwater system and obtaining an improved estimation for the increase in recharge during glacier times at the Texas and Utah locations would be useful. Several stragegies are presented for accomplishing this work. 94 references, 27 figures, 5 tables.

  12. Design of Pinion Machine Tool-settings for Spiral Bevel Gears by Controlling Contact Path and Transmission Errors

    Institute of Scientific and Technical Information of China (English)

    Cao Xuemei; Fang Zongde; Xu Hao; Su Jinzhan

    2008-01-01

    This paper proposes a new approach to design pinion machine tool-settings for spiral bevel gears by controlling contact path and transmis- sion errors. It is based on the satisfaction of contact condition of three given control points on the tooth surface. The three meshing points are controlled to be on a predesigned straight contact path that meets the pre-designed parabolic function of transmission errors. Designed separately, the magnitude of transmission errors and the orientation of the contact path are subjected to precise control. In addition, in order to meet the manufacturing requirements, we suggest to modify the values of blank offset, one of the pinion machine tool-settings, and redesign pinion ma- chine tool-settings to ensure that the magnitude and the geometry of transmission errors should not be influenced apart from minor effects on the predesigned straight contact path. The proposed approach together with its ideas has been proven by a numerical example and the manufacturing practice of a pair of spiral bevel gears.

  13. Transmission Intensity and Drug Resistance in Malaria Population Dynamics : Implications for Climate Change

    NARCIS (Netherlands)

    Artzy-Randrup, Yael; Alonso, David; Pascual, Mercedes

    2010-01-01

    Although the spread of drug resistance and the influence of climate change on malaria are most often considered separately, these factors have the potential to interact through altered levels of transmission intensity. The influence of transmission intensity on the evolution of drug resistance has b

  14. Optimal detection of a change-set in a spatial Poisson process

    CERN Document Server

    Ivanoff, B Gail; 10.1214/09-AAP629

    2010-01-01

    We generalize the classic change-point problem to a "change-set" framework: a spatial Poisson process changes its intensity on an unobservable random set. Optimal detection of the set is defined by maximizing the expected value of a gain function. In the case that the unknown change-set is defined by a locally finite set of incomparable points, we present a sufficient condition for optimal detection of the set using multiparameter martingale techniques. Two examples are discussed.

  15. Age-related changes in the transmission properties of the human lens and their relevance to circadian entrainment

    DEFF Research Database (Denmark)

    Kessel, Line; Lundeman, Jesper Holm; Herbst, Kristina;

    2010-01-01

    To characterize age-related changes in the transmission of light through noncataractous human lenses.......To characterize age-related changes in the transmission of light through noncataractous human lenses....

  16. HIV transmission in the dental setting and the HIV-infected oral health care professional: workshop 1C.

    LENUS (Irish Health Repository)

    Flint, S R

    2011-04-01

    This workshop addressed two important issues: first, the global evidence of HIV transmission from health care provider to patient and from patient to health care provider in the general health care environment and the dental practice setting; second, in the era of highly active antiretroviral therapy, whether oral health care professionals living with HIV pose a risk of transmission to their patients and whether standard infection control is adequate to protect both the patient and the oral health care professional in dental practice. The workshop culminated in a general discussion and the formulation of a consensus statement from the participating delegates, representing more than 30 countries, on the criteria under which an HIV-infected oral health care professional might practice dentistry without putting patients at risk. This consensus statement, the Beijing Declaration, was agreed nem con.

  17. Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination.

    Science.gov (United States)

    Otter, J A; Donskey, C; Yezli, S; Douthwaite, S; Goldenberg, S D; Weber, D J

    2016-03-01

    Viruses with pandemic potential including H1N1, H5N1, and H5N7 influenza viruses, and severe acute respiratory syndrome (SARS)/Middle East respiratory syndrome (MERS) coronaviruses (CoV) have emerged in recent years. SARS-CoV, MERS-CoV, and influenza virus can survive on surfaces for extended periods, sometimes up to months. Factors influencing the survival of these viruses on surfaces include: strain variation, titre, surface type, suspending medium, mode of deposition, temperature and relative humidity, and the method used to determine the viability of the virus. Environmental sampling has identified contamination in field-settings with SARS-CoV and influenza virus, although the frequent use of molecular detection methods may not necessarily represent the presence of viable virus. The importance of indirect contact transmission (involving contamination of inanimate surfaces) is uncertain compared with other transmission routes, principally direct contact transmission (independent of surface contamination), droplet, and airborne routes. However, influenza virus and SARS-CoV may be shed into the environment and be transferred from environmental surfaces to hands of patients and healthcare providers. Emerging data suggest that MERS-CoV also shares these properties. Once contaminated from the environment, hands can then initiate self-inoculation of mucous membranes of the nose, eyes or mouth. Mathematical and animal models, and intervention studies suggest that contact transmission is the most important route in some scenarios. Infection prevention and control implications include the need for hand hygiene and personal protective equipment to minimize self-contamination and to protect against inoculation of mucosal surfaces and the respiratory tract, and enhanced surface cleaning and disinfection in healthcare settings.

  18. Strategies for controlling non-transmissible infection outbreaks using a large human movement data set.

    Directory of Open Access Journals (Sweden)

    Penelope A Hancock

    2014-09-01

    Full Text Available Prediction and control of the spread of infectious disease in human populations benefits greatly from our growing capacity to quantify human movement behavior. Here we develop a mathematical model for non-transmissible infections contracted from a localized environmental source, informed by a detailed description of movement patterns of the population of Great Britain. The model is applied to outbreaks of Legionnaires' disease, a potentially life-threatening form of pneumonia caused by the bacteria Legionella pneumophilia. We use case-report data from three recent outbreaks that have occurred in Great Britain where the source has already been identified by public health agencies. We first demonstrate that the amount of individual-level heterogeneity incorporated in the movement data greatly influences our ability to predict the source location. The most accurate predictions were obtained using reported travel histories to describe movements of infected individuals, but using detailed simulation models to estimate movement patterns offers an effective fast alternative. Secondly, once the source is identified, we show that our model can be used to accurately determine the population likely to have been exposed to the pathogen, and hence predict the residential locations of infected individuals. The results give rise to an effective control strategy that can be implemented rapidly in response to an outbreak.

  19. Strategies for controlling non-transmissible infection outbreaks using a large human movement data set.

    Science.gov (United States)

    Hancock, Penelope A; Rehman, Yasmin; Hall, Ian M; Edeghere, Obaghe; Danon, Leon; House, Thomas A; Keeling, Matthew J

    2014-09-01

    Prediction and control of the spread of infectious disease in human populations benefits greatly from our growing capacity to quantify human movement behavior. Here we develop a mathematical model for non-transmissible infections contracted from a localized environmental source, informed by a detailed description of movement patterns of the population of Great Britain. The model is applied to outbreaks of Legionnaires' disease, a potentially life-threatening form of pneumonia caused by the bacteria Legionella pneumophilia. We use case-report data from three recent outbreaks that have occurred in Great Britain where the source has already been identified by public health agencies. We first demonstrate that the amount of individual-level heterogeneity incorporated in the movement data greatly influences our ability to predict the source location. The most accurate predictions were obtained using reported travel histories to describe movements of infected individuals, but using detailed simulation models to estimate movement patterns offers an effective fast alternative. Secondly, once the source is identified, we show that our model can be used to accurately determine the population likely to have been exposed to the pathogen, and hence predict the residential locations of infected individuals. The results give rise to an effective control strategy that can be implemented rapidly in response to an outbreak.

  20. Picture this: Managed change and resistance in business network settings

    DEFF Research Database (Denmark)

    Kragh, Hanne; Andersen, Poul Houman

    2009-01-01

    This paper discusses change management in networks. The literature on business networks tends to downplay the role of managerial initiative in network change. The change management literature addresses such initiative, but with its single-firm perspective it overlooks the interdependence of network...... context characterized by limited managerial authority over these activities. Our analysis suggests that change efforts unfold as a negotiated process during which the change project is re-negotiated to fit the multiple actor constituencies. The degree of overlap in the co-existing network pictures...

  1. The dependence of the abstract boundary classification on a set of curves II: How the classification changes when the bounded parameter property satisfying set of curves changes

    CERN Document Server

    Whale, B E

    2012-01-01

    The abstract boundary uses sets of curves with the bounded parameter property (b.p.p.) to classify the elements of the abstract boundary into regular points, singular points, points at infinity and so on. Building on the material of Part one of this two part series, we show how this classification changes when the set of b.p.p. satisfying curves changes.

  2. Long-term effects of penicillin resistance and fitness cost on pneumococcal transmission dynamics in a developed setting

    Directory of Open Access Journals (Sweden)

    Diana Tilevik

    2016-05-01

    Full Text Available Background: The increasing prevalence of penicillin non-susceptible pneumococci (PNSP throughout the world threatens successful treatment of infections caused by this important bacterial pathogen. The rate at which PNSP clones spread in the community is thought to mainly be determined by two key determinants; the volume of penicillin use and the magnitude of the fitness cost in the absence of treatment. The aim of the study was to determine the impacts of penicillin consumption and fitness cost on pneumococcal transmission dynamics in a developed country setting. Methods: An individual-based network model based on real-life demographic data was constructed and applied in a developed country setting (Sweden. A population structure with transmission of carriage taking place within relevant mixing groups, i.e. families, day care groups, school classes, and other close contacts, was considered to properly assess the transmission dynamics for susceptible and PNSP clones. Several scenarios were simulated and model outcomes were statistically analysed. Results: Model simulations predicted that with an outpatient penicillin use corresponding to the sales in Sweden 2010 (118 recipes per 1,000 inhabitants per year, the magnitude of a fitness cost for resistance must be at least 5% to offset the advantage of penicillin resistance. Moreover, even if there is a fitness cost associated with penicillin resistance, a considerable reduction of penicillin usage appears to be required to significantly decrease the incidence of PNSP in a community. Conclusion: The frequency of PNSP clones is hard to reverse by simply reducing the penicillin consumption even if there is a biological cost associated with resistance. However, because penicillin usage does promote further spread of PNSP clones, it is important to keep down penicillin consumption considering future resistance problems.

  3. Transmission of Middle East Respiratory Syndrome Coronavirus Infections in Healthcare Settings, Abu Dhabi

    Science.gov (United States)

    Nguyen, Duc; Aden, Bashir; Al Bandar, Zyad; Al Dhaheri, Wafa; Abu Elkheir, Kheir; Khudair, Ahmed; Al Mulla, Mariam; El Saleh, Feda; Imambaccus, Hala; Al Kaabi, Nawal; Sheikh, Farrukh Amin; Sasse, Jurgen; Turner, Andrew; Abdel Wareth, Laila; Weber, Stefan; Al Ameri, Asma; Abu Amer, Wesal; Alami, Negar N.; Bunga, Sudhir; Haynes, Lia M.; Hall, Aron J.; Kallen, Alexander J.; Kuhar, David; Pham, Huong; Pringle, Kimberly; Tong, Suxiang; Whitaker, Brett L.; Gerber, Susan I.; Al Hosani, Farida Ismail

    2016-01-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) infections sharply increased in the Arabian Peninsula during spring 2014. In Abu Dhabi, United Arab Emirates, these infections occurred primarily among healthcare workers and patients. To identify and describe epidemiologic and clinical characteristics of persons with healthcare-associated infection, we reviewed laboratory-confirmed MERS-CoV cases reported to the Health Authority of Abu Dhabi during January 1, 2013–May 9, 2014. Of 65 case-patients identified with MERS-CoV infection, 27 (42%) had healthcare-associated cases. Epidemiologic and genetic sequencing findings suggest that 3 healthcare clusters of MERS-CoV infection occurred, including 1 that resulted in 20 infected persons in 1 hospital. MERS-CoV in healthcare settings spread predominantly before MERS-CoV infection was diagnosed, underscoring the importance of increasing awareness and infection control measures at first points of entry to healthcare facilities. PMID:26981708

  4. Transmission of Middle East Respiratory Syndrome Coronavirus Infections in Healthcare Settings, Abu Dhabi.

    Science.gov (United States)

    Hunter, Jennifer C; Nguyen, Duc; Aden, Bashir; Al Bandar, Zyad; Al Dhaheri, Wafa; Abu Elkheir, Kheir; Khudair, Ahmed; Al Mulla, Mariam; El Saleh, Feda; Imambaccus, Hala; Al Kaabi, Nawal; Sheikh, Farrukh Amin; Sasse, Jurgen; Turner, Andrew; Abdel Wareth, Laila; Weber, Stefan; Al Ameri, Asma; Abu Amer, Wesal; Alami, Negar N; Bunga, Sudhir; Haynes, Lia M; Hall, Aron J; Kallen, Alexander J; Kuhar, David; Pham, Huong; Pringle, Kimberly; Tong, Suxiang; Whitaker, Brett L; Gerber, Susan I; Al Hosani, Farida Ismail

    2016-04-01

    Middle East respiratory syndrome coronavirus (MERS-CoV) infections sharply increased in the Arabian Peninsula during spring 2014. In Abu Dhabi, United Arab Emirates, these infections occurred primarily among healthcare workers and patients. To identify and describe epidemiologic and clinical characteristics of persons with healthcare-associated infection, we reviewed laboratory-confirmed MERS-CoV cases reported to the Health Authority of Abu Dhabi during January 1, 2013-May 9, 2014. Of 65 case-patients identified with MERS-CoV infection, 27 (42%) had healthcare-associated cases. Epidemiologic and genetic sequencing findings suggest that 3 healthcare clusters of MERS-CoV infection occurred, including 1 that resulted in 20 infected persons in 1 hospital. MERS-CoV in healthcare settings spread predominantly before MERS-CoV infection was diagnosed, underscoring the importance of increasing awareness and infection control measures at first points of entry to healthcare facilities.

  5. Evaluation of 4 weeks' neonatal antiretroviral prophylaxis as a component of a prevention of mother-to-child transmission program in a resource-rich setting.

    LENUS (Irish Health Repository)

    Ferguson, Wendy

    2011-05-01

    In resource-rich settings, universal adoption of a 4- rather than 6-week neonatal antiretroviral (ARV) prophylaxis regimen could reduce toxicity and results in cost savings, provided prevention of mother-to-child transmission program effectiveness is not compromised.

  6. Multi-step simultaneous changes Constructive Heuristic Algorithm for Transmission Network Expansion Planning

    Energy Technology Data Exchange (ETDEWEB)

    Bustamante-Cedeno, Enrique; Arora, Sant [Industrial and Systems Engineering Division, Mechanical Engineering Department, University of Minnesota, 111 Church Street, S.E., Minneapolis, MN 55455 (United States)

    2009-04-15

    In this paper, a Constructive Heuristic Algorithm (CHA) is presented to solve the Transmission Network Expansion Planning Problem (TNEP), a complex non-convex Mixed Integer Non-Linear Programming (MINLP) problem with multiple local minima. In the proposed algorithm, the non-linearities are resolved through the following feature: when discrete decision variables are given, the model becomes linear in the continuous variables. A CHA is developed which improves the current solution by implementing multiple step simultaneous changes over a number of saturated transmission lines, in contrast to the approach traditionally followed, which implements one change at a time. Solutions to test problems are computed. (author)

  7. Monolingual Teachers in Multilingual Settings: Changing Attitudes and Practices

    Science.gov (United States)

    Pritchard, Robert

    2012-01-01

    This article describes a 6-year, districtwide staff-development project that was implemented in an attempt to change teacher attitudes and practices as they relate to English learners (ELs). The specific goals of the project were (a) to help the district's teachers develop the knowledge base, pedagogical skills, and professional attitudes required…

  8. Wolof Noun Classification: The Social Setting of Divergent Change

    Science.gov (United States)

    Irvine, Judith T.

    1978-01-01

    Ongoing change in Wolof noun classification is traced by comparing nineteenth-century linguistic evidence with modern sociolinguistic data. Upwardly mobile middle-aged men of high caste tend to reduce the noun class system, whereas other speakers tend to elaborate it. (Author/RM)

  9. Dynamics of shigellosis epidemics: estimating individual-level transmission and reporting rates from national epidemiologic data sets.

    Science.gov (United States)

    Joh, Richard I; Hoekstra, Robert M; Barzilay, Ezra J; Bowen, Anna; Mintz, Eric D; Weiss, Howard; Weitz, Joshua S

    2013-10-15

    Shigellosis, a diarrheal disease, is endemic worldwide and is responsible for approximately 15,000 laboratory-confirmed cases in the United States every year. However, patients with shigellosis often do not seek medical care. To estimate the burden of shigellosis, we extended time-series susceptible-infected-recovered models to infer epidemiologic parameters from underreported case data. We applied the time-series susceptible-infected-recovered-based inference schemes to analyze the largest surveillance data set of Shigella sonnei in the United States from 1967 to 2007 with county-level resolution. The dynamics of shigellosis transmission show strong annual and multiyear cycles, as well as seasonality. By using the schemes, we inferred individual-level parameters of shigellosis infection, including seasonal transmissibilities and basic reproductive number (R0). In addition, this study provides quantitative estimates of the reporting rate, suggesting that the shigellosis burden in the United States may be more than 10 times the number of laboratory-confirmed cases. Although the estimated reporting rate is generally under 20%, and R0 is generally under 1.5, there is a strong negative correlation between estimates of the reporting rate and R0. Such negative correlations are likely to pose identifiability problems in underreported diseases. We discuss complementary approaches that might further disentangle the true reporting rate and R0.

  10. A lesson from Argentina: Setting transmission tolls in a competitive auction is much better than regulating them

    Energy Technology Data Exchange (ETDEWEB)

    Galetovic, Alexander [Facultad de Ciencias Economicas y Empresariales, Av. San Carlos de Apoquindo 2200, Santiago (Chile); Inostroza, Juan Ricardo [AES Gener S.A., Sanchez Fontecilla 310, piso 3, Santiago (Chile)

    2008-07-15

    There are at least two procedures for setting the tolls paid by power line users. One consists of regulating them in a standard process. The other, which is used in Argentina, involves auctioning the lines to the lowest toll. In this paper we show that an auction yields higher expected social welfare if n {>=} 2 bid. Expected social welfare is even higher if, as in Argentina, those who benefit from the line can also bid and build. Moreover, when the social welfare is utilitarian, an auction beats regulation even when the regulator can perfectly audit costs ex post. We describe and examine the auction of the fourth Comahue transmission line in Argentina. Assuming that the regulator's information about costs is similar to the information held by the industry, the model suggests that had tolls been regulated, they would have been at least 61% higher. (author)

  11. Gender Writ Small: Gender Enactments and Gendered Narratives about Lab Organization and Knowledge Transmission in a Biomedical Engineering Research Setting

    Science.gov (United States)

    Malone, Kareen Ror; Nersessian, Nancy J.; Newstetter, Wendy

    This article presents qualitative data and offers some innovative theoretical approaches to frame the analysis of gender in science, technology, engineering, and mathematics (STEM) settings. It begins with a theoretical discussion of a discursive approach to gender that captures how gender is lived "on the ground." The authors argue for a less individualistic approach to gender. Data for this research project was gathered from intensive interviews with lab members and ethnographic observations in a biomedical engineering lab. Data analysis relied on a mixed methodology involving qualitative approaches and dialogues with findings from other research traditions. Three themes are highlighted: lab dynamics in relation to issues of critical mass, the division of labor, and knowledge transmission. The data illustrate how gender is created in interactions and is inflected through forms of social organization.

  12. Climate change, population immunity, and hyperendemicity in the transmission threshold of dengue.

    Directory of Open Access Journals (Sweden)

    Mika Oki

    Full Text Available BACKGROUND: It has been suggested that the probability of dengue epidemics could increase because of climate change. The probability of epidemics is most commonly evaluated by the basic reproductive number (R(0, and in mosquito-borne diseases, mosquito density (the number of female mosquitoes per person [MPP] is the critical determinant of the R(0 value. In dengue-endemic areas, 4 different serotypes of dengue virus coexist-a state known as hyperendemicity-and a certain proportion of the population is immune to one or more of these serotypes. Nevertheless, these factors are not included in the calculation of R(0. We aimed to investigate the effects of temperature change, population immunity, and hyperendemicity on the threshold MPP that triggers an epidemic. METHODS AND FINDINGS: We designed a mathematical model of dengue transmission dynamics. An epidemic was defined as a 10% increase in seroprevalence in a year, and the MPP that triggered an epidemic was defined as the threshold MPP. Simulations were conducted in Singapore based on the recorded temperatures from 1980 to 2009 The threshold MPP was estimated with the effect of (1 temperature only; (2 temperature and fluctuation of population immunity; and (3 temperature, fluctuation of immunity, and hyperendemicity. When only the effect of temperature was considered, the threshold MPP was estimated to be 0.53 in the 1980s and 0.46 in the 2000s, a decrease of 13.2%. When the fluctuation of population immunity and hyperendemicity were considered in the model, the threshold MPP decreased by 38.7%, from 0.93 to 0.57, from the 1980s to the 2000s. CONCLUSIONS: The threshold MPP was underestimated if population immunity was not considered and overestimated if hyperendemicity was not included in the simulations. In addition to temperature, these factors are particularly important when quantifying the threshold MPP for the purpose of setting goals for vector control in dengue-endemic areas.

  13. Setting priorities for land management to mitigate climate change

    Directory of Open Access Journals (Sweden)

    Böttcher Hannes

    2012-03-01

    Full Text Available Abstract Background No consensus has been reached how to measure the effectiveness of climate change mitigation in the land-use sector and how to prioritize land use accordingly. We used the long-term cumulative and average sectorial C stocks in biomass, soil and products, C stock changes, the substitution of fossil energy and of energy-intensive products, and net present value (NPV as evaluation criteria for the effectiveness of a hectare of productive land to mitigate climate change and produce economic returns. We evaluated land management options using real-life data of Thuringia, a region representative for central-western European conditions, and input from life cycle assessment, with a carbon-tracking model. We focused on solid biomass use for energy production. Results In forestry, the traditional timber production was most economically viable and most climate-friendly due to an assumed recycling rate of 80% of wood products for bioenergy. Intensification towards "pure bioenergy production" would reduce the average sectorial C stocks and the C substitution and would turn NPV negative. In the forest conservation (non-use option, the sectorial C stocks increased by 52% against timber production, which was not compensated by foregone wood products and C substitution. Among the cropland options wheat for food with straw use for energy, whole cereals for energy, and short rotation coppice for bioenergy the latter was most climate-friendly. However, specific subsidies or incentives for perennials would be needed to favour this option. Conclusions When using the harvested products as materials prior to energy use there is no climate argument to support intensification by switching from sawn-wood timber production towards energy-wood in forestry systems. A legal framework would be needed to ensure that harvested products are first used for raw materials prior to energy use. Only an effective recycling of biomaterials frees land for long

  14. Changes in Variable Number of Tandem Repeats in 'Candidatus Liberibacter asiaticus' through Insect Transmission.

    Directory of Open Access Journals (Sweden)

    Hiroshi Katoh

    Full Text Available Citrus greening (huanglongbing is the most destructive citrus disease worldwide. The disease is associated with three species of 'Candidatus Liberibacter' among which 'Ca. Liberibacter asiaticus' has the widest distribution. 'Ca. L. asiaticus' is commonly transmitted by a phloem-feeding insect vector, the Asian citrus psyllid Diaphorina citri. A previous study showed that isolates of 'Ca. L. asiaticus' were clearly differentiated by variable number of tandem repeat (VNTR profiles at four loci in the genome. In this study, the VNTR analysis was further validated by assessing the stability of these repeats after multiplication of the pathogen upon host-to-host transmission using a 'Ca. L. asiaticus' strain from Japan. The results showed that some tandem repeats showed detectable changes after insect transmission. To our knowledge, this is the first report to demonstrate that the repeat numbers VNTR 002 and 077 of 'Ca. L. asiaticus' change through psyllid transmission. VNTRs in the recipient plant were apparently unrelated to the growing phase of the vector. In contrast, changes in the number of tandem repeats increased with longer acquisition and inoculation access periods, whereas changes were not observed through psyllid transmission after relatively short acquisition and inoculation access periods, up to 20 and 19 days, respectively.

  15. Using serological measures to monitor changes in malaria transmission in Vanuatu

    Directory of Open Access Journals (Sweden)

    Clements Archie

    2010-06-01

    Full Text Available Abstract Background With renewed interest in malaria elimination, island environments present unique opportunities to achieve this goal. However, as transmission decreases, monitoring and evaluation programmes need increasingly sensitive tools to assess Plasmodium falciparum and Plasmodium vivax exposure. In 2009, to assess the role of serological markers in evaluating malaria transmission, a cross-sectional seroprevalence study was carried out in Tanna and Aneityum, two of the southernmost islands of the Vanuatu archipelago, areas where malaria transmission has been variably reduced over the past few decades. Methods Malaria transmission was assessed using serological markers for exposure to P. falciparum and P. vivax. Filter blood spot papers were collected from 1,249 people from Tanna, and 517 people from Aneityum to assess the prevalence of antibodies to two P. falciparum antigens (MSP-119 and AMA-1 and two P. vivax antigens (MSP-119 and AMA-1. Age-specific prevalence was modelled using a simple catalytic conversion model based on maximum likelihood to generate a community seroconversion rate (SCR. Results Overall seropositivity in Tanna was 9.4%, 12.4% and 16.6% to P. falciparum MSP-119, AMA-1 and Schizont Extract respectively and 12.6% and 15.0% to P. vivax MSP-119 and AMA-1 respectively. Serological results distinguished between areas of differential dominance of either P. vivax or P. falciparum and analysis of age-stratified results showed a step in seroprevalence occurring approximately 30 years ago on both islands, indicative of a change in transmission intensity at this time. Results from Aneityum suggest that several children may have been exposed to malaria since the 2002 P. vivax epidemic. Conclusion Seroepidemiology can provide key information on malaria transmission for control programmes, when parasite rates are low. As Vanuatu moves closer to malaria elimination, monitoring changes in transmission intensity and identification

  16. Community-associated methicillin-resistant Staphylococcus aureus transmission in households of infected cases : a pooled analysis of primary data from three studies across international settings

    NARCIS (Netherlands)

    Knox, J; Van Rijen, M; Uhlemann, A-C; Miller, M; Hafer, C; Vavagiakis, P; Shi, Q; Johnson, P D R; Coombs, G; Kluytmans-Van Den Bergh, M; Kluytmans, J; Bennett, C M; Lowy, F D

    2015-01-01

    Diverse strain types of methicillin-resistant Staphylococcus aureus (MRSA) cause infections in community settings worldwide. To examine heterogeneity of spread within households and to identify common risk factors for household transmission across settings, primary data from studies conducted in New

  17. Climate change impacts on West Nile virus transmission in a global context.

    Science.gov (United States)

    Paz, Shlomit

    2015-04-05

    West Nile virus (WNV), the most widely distributed virus of the encephalitic flaviviruses, is a vector-borne pathogen of global importance. The transmission cycle exists in rural and urban areas where the virus infects birds, humans, horses and other mammals. Multiple factors impact the transmission and distribution of WNV, related to the dynamics and interactions between pathogen, vector, vertebrate hosts and environment. Hence, among other drivers, weather conditions have direct and indirect influences on vector competence (the ability to acquire, maintain and transmit the virus), on the vector population dynamic and on the virus replication rate within the mosquito, which are mostly weather dependent. The importance of climatic factors (temperature, precipitation, relative humidity and winds) as drivers in WNV epidemiology is increasing under conditions of climate change. Indeed, recent changes in climatic conditions, particularly increased ambient temperature and fluctuations in rainfall amounts, contributed to the maintenance (endemization process) of WNV in various locations in southern Europe, western Asia, the eastern Mediterranean, the Canadian Prairies, parts of the USA and Australia. As predictions show that the current trends are expected to continue, for better preparedness, any assessment of future transmission of WNV should take into consideration the impacts of climate change.

  18. Community-based approaches for prevention of mother to child transmission in resource-poor settings: a social ecological review

    Directory of Open Access Journals (Sweden)

    Leila Katirayi

    2012-07-01

    Full Text Available Introduction: Numerous barriers to optimal uptake of prevention of mother to child transmission (PMTCT services occur at community level (i.e., outside the healthcare setting. To achieve elimination of paediatric HIV, therefore, interventions must also work within communities to address these barriers and increase service use and need to be informed by evidence. This paper reviews community-based approaches that have been used in resource-limited settings to increase rates of PMTCT enrolment, retention in care and successful treatment outcomes. It aims to identify which interventions work, why they may do so and what knowledge gaps remain. Methods: First, we identified barriers to PMTCT that originate outside the health system. These were used to construct a social ecological framework categorizing barriers to PMTCT into the following levels of influence: individual, peer and family, community and sociocultural. We then used this conceptual framework to guide a review of the literature on community-based approaches, defined as interventions delivered outside of formal health settings, with the goal of increasing uptake, retention, adherence and positive psychosocial outcomes in PMTCT programmes in resource-poor countries. Results: Our review found evidence of effectiveness of strategies targeting individuals and peer/family levels (e.g., providing household HIV testing and training peer counsellors to support exclusive breastfeeding and at community level (e.g., participatory women's groups and home-based care to support adherence and retention. Evidence is more limited for complex interventions combining multiple strategies across different ecological levels. There is often little information describing implementation; and approaches such as “community mobilization” remain poorly defined. Conclusions: Evidence from existing community approaches can be adapted for use in planning PMTCT. However, for successful replication of evidence

  19. Underwater asymmetric acoustic transmission structure using the medium with gradient change of impedance

    Science.gov (United States)

    Bo, Hu; Jie, Shi; Sheng-Guo, Shi; Yu, Sun; Zhong-Rui, Zhu

    2016-02-01

    We propose an underwater asymmetric acoustic transmission structure comprised of two media each with a gradient change of acoustic impedance. By gradually increasing the acoustic impedances of the media, the propagating direction of the acoustic wave can be continuously bent, resulting in allowing the acoustic wave to pass through along the positive direction and blocking acoustic waves from the negative one. The main advantages of this structure are that the asymmetric transmission effect of this structure can be realized and enhanced more easily in water. We investigate both numerically and experimentally the asymmetric transmission effect. The experimental results show that a highly efficient asymmetric acoustic transmission can be yielded within a remarkable broadband frequency range, which agrees well with the numerical prediction. It is of potential practical significance for various underwater applications such as reducing vibration and noise. Project supported by the National Natural Science Foundation of China (Grant Nos. 11204049 and 11204050), the Program for Changjiang Scholars and Innovative Research Team in University of Ministry of Education of China (Grant No. IRT1228), and the Specialized Research Fund for the Doctoral Program of Higher Education of China (Grant Nos. 20122304120023 and 20122304120011).

  20. Tracing defaulters in HIV prevention of mother-to-child transmission programmes through community health workers: results from a rural setting in Zimbabwe

    Directory of Open Access Journals (Sweden)

    Florian Vogt

    2015-10-01

    test result collection. Conclusions: The CHW-DT intervention did not reduce perinatal HIV transmission significantly. Retention improved moderately during the post-natal period, but cumulative retention decreased rapidly even after the intervention. We showed that transmission in resource-limited settings can be as low as in resource-rich countries if patients are fully retained in care. This requires structural changes to the regular PMTCT services, in which community health workers can, at best, play a complementary role.

  1. Prevention of Parent to Child Transmission (PPTCT program data in India: an emerging data set for appraising the HIV epidemic.

    Directory of Open Access Journals (Sweden)

    Sema K Sgaier

    Full Text Available BACKGROUND: Evidence based resource allocation and decentralized planning of an effective HIV/AIDS response requires reliable information on levels and trends of HIV at national and sub-national geographic levels. HIV sentinel surveillance data from antenatal clinics (HSS-ANC has been an important data source to assess the HIV/AIDS epidemic in India, but has a number of limitations. We assess the value of Prevention of Parent to Child Transmission (PPTCT programme data to appraise the HIV epidemic in India. METHODS/FINDINGS: HIV data from PPTCT sites were compared to HSS-ANC and general population level surveys at various geographic levels in the states of Karnataka, Maharashtra and Andhra Pradesh. Chi-square tests were used to ascertain statistical significance. PPTCT HIV prevalence was significantly lower than HSS-ANC HIV prevalence (0.92% vs. 1.22% in Andhra Pradesh, 0.65% vs. 0.89% in Karnataka, 0.52% vs. 0.60% in Maharashtra, p<0.001 for all three states. In all three states, HIV prevalence from PPTCT centres that were part of the sentinel surveillance was comparable to HSS-ANC prevalence but significantly higher than PPTCT centres that were not part of the sentinel surveillance. HIV prevalence from PPTCT data was comparable to that from general population surveys. In all three states, significant declines in HIV prevalence between 2007 and 2010 were observed with the PPTCT data set. District level analyses of HIV trends and sub-district level analysis of HIV prevalence were possible using the PPTCT and not the HSS-ANC data sets. CONCLUSION: HIV prevalence from PPTCT may be a better proxy for general population prevalence than HSS-ANC. PPTCT data allow for analysis of HIV prevalence and trends at smaller geographic units, which is important for decentralized planning of HIV/AIDS programming. With further improvements to the system, India could replace its HSS-ANC with PPTCT programme data for surveillance.

  2. Transmissibility studies of vacuolar changes in the rostral colliculus of pigs

    Directory of Open Access Journals (Sweden)

    Spencer Yvonne I

    2009-09-01

    Full Text Available Abstract Background Histopathological examinations of brains from healthy pigs have revealed localised vacuolar changes, predominantly in the rostral colliculus, that are similar to the neuropil vacuolation featured in the transmissible spongiform encephalopathies and have been described in pigs challenged parenterally with the agent causing bovine spongiform encephalopathy (BSE. Feedstuff containing BSE-contaminated meat and bone meal (MBM may have been fed to pigs prior to the ban of mammalian MBM in feed of farmed livestock in the United Kingdom in 1996, but there is no evidence of the natural occurrence of a transmissible spongiform encephalopathy (TSE in the domestic pig. Furthermore, experimental transmission of BSE to pigs by the oral route has been unsuccessful. A study was conducted to investigate whether the localised vacuolar changes in the porcine brain were associated with a transmissible aetiology and therefore biologically significant. Two groups of ten pigs were inoculated parenterally with vacuolated rostral colliculus from healthy pigs either born before 1996 or born after 1996. Controls included ten pigs similarly inoculated with rostral colliculus from New Zealand-derived pigs and nine pigs inoculated with a bovine BSE brain homogenate. Results None of the pigs inoculated with rostral colliculus developed a TSE-like neurological disease up to five years post inoculation when the study was terminated, and disease-associated prion protein, PrPd, was not detected in the brains of these pigs. By contrast, eight of nine BSE-inoculated pigs developed neurological signs, two of which had detectable PrPd by postmortem tests. No significant histopathological changes were detected to account for the clinical signs in the PrPd-negative, BSE-inoculated pigs. Conclusion The findings in this study suggest that vacuolation in the porcine rostral colliculus is not caused by a transmissible agent and is probably a clinically insignificant

  3. Changes in corticospinal transmission following 8 weeks of ankle joint immobilization

    DEFF Research Database (Denmark)

    Leukel, Christian; Taube, Wolfgang; Rittweger, Jörn;

    2015-01-01

    ) of the primary motor cortex (Hcond). This method allows assessment of transmission in fast (monosynaptic) and slow(er) (polysynaptic) corticospinal pathways. METHODS: 9 subjects underwent 8weeks of unilateral ankle joint immobilization during daytime, 7 subjects served as controls. The measures obtained before...... immobilization. Importantly, Hcond revealed significant facilitation of conditioned reflexes, but only for longer conditioning intervals, suggesting that immobilization increased excitability only of slower, indirect corticospinal pathways. No changes were observed in the control group. Immobilization had...... no significant effects on spinal reflex measures. CONCLUSIONS: 8weeks of ankle joint immobilization was accompanied by pathway-specific modulation of corticospinal transmission. SIGNIFICANCE: It is particularly interesting that fast corticospinal projections were unaffected as these are involved in controlling...

  4. Resource Manual for Handling Body Fluids in the School Setting To Prevent Transmission of Human Immunodeficiency Virus and Hepatitis B Virus. Revised Edition.

    Science.gov (United States)

    Maryland State Dept. of Health and Mental Hygiene, Baltimore.

    This Maryland resource manual provides local education agencies with guidelines on how to handle body fluids to prevent the transmission of diseases, especially Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV), in the school setting. The first section summarizes the reasons for development of the manual. The second section summarizes…

  5. Resource Manual for Handling Body Fluids in the School Setting To Prevent the Transmission of Human Immunodeficiency Virus and Hepatitis B Virus.

    Science.gov (United States)

    Maryland State Dept. of Health and Mental Hygiene, Baltimore.

    Guidelines to prevent the transmission of blood-borne diseases, especially those caused by the Human Immunodeficiency Virus (HIV) and the Hepatitis B Virus (HBV), in the school setting are provided in this resource manual for school staff. Sections include information on the reasons for the development of this manual; a summary of the means of HIV…

  6. A transcutaneous energy transmission system for artificial heart adapting to changing impedance.

    Science.gov (United States)

    Fu, Yang; Hu, Liang; Ruan, Xiaodong; Fu, Xin

    2015-04-01

    This article presents a coil-coupling-based transcutaneous energy transmission system (TETS) for wirelessly powering an implanted artificial heart. Keeping high efficiency is especially important for TETS, which is usually difficult due to transmission impedance changes in practice, which are commonly caused by power requirement variation for different body movements and coil-couple malposition accompanying skin peristalsis. The TETS introduced in this article is designed based on a class-E power amplifier (E-PA), of which efficiency is over 95% when its load is kept in a certain range. A resonance matching and impedance compressing functions coupled network based on parallel-series capacitors is proposed in the design, to enhance the energy transmission efficiency and capacity of the coil-couple through resonating, and meanwhile compress the changing range of the transmission impedance to meet the load requirements of the E-PA and thus keep the high efficiency of TETS. An analytical model of the designed TETS is built to analyze the effect of the network and also provide bases for following parameters determination. Then, according algorithms are provided to determine the optimal parameters required in the TETS for good performance both in resonance matching and impedance compressing. The design is tested by a series of experiments, which validate that the TETS can transmit a wide range of power with a total efficiency of at least 70% and commonly beyond 80%, even when the coil-couple is seriously malpositioned. The design methodology proposed in this article can be applied to any existing TETS based on E-PA to improve their performance in actual applications.

  7. Employing injection-locked FP LDs to set up a hybrid CATV/MW/MMW WDM light wave transmission system.

    Science.gov (United States)

    Lin, Chun-Yu; Lu, Hai-Han; Li, Chung-Yi; Wu, Po-Yi; Peng, Peng-Chun; Jhang, Tai-Wei; Lin, Che-Yu

    2014-07-01

    A hybrid cable television (CATV)/microwave (MW)/millimeter-wave (MMW) wavelength-division-multiplexing (WDM) light wave transmission system based on injection-locked Fabry-Perot laser diodes (FP LDs) is proposed and demonstrated. Different from conventional hybrid WDM light wave transmission systems, which need wavelength-selected distributed feedback laser diodes to support various services, the proposed systems employ injection-locked FP LDs to provide multiple applications. Over a 40 km single-mode fiber transport, impressive performances of carrier-to-noise ratio/composite second-order/composite triple-beat/bit error rate are obtained for 550 MHz CATV/20 GHz MW/40 GHz MMW/60 GHz MMW signal transmissions. Such a hybrid WDM light wave transmission system would be attractive for fiber links to provide broadband integrated services.

  8. Priority setting in family change and clinical practice: the Family FIRO Model.

    Science.gov (United States)

    Doherty, W J; Colangelo, N; Hovander, D

    1991-06-01

    We update a theoretical framework for understanding priority setting for the management of family change, with special emphasis on developmental change. We propose that three core dimensions of family interaction--inclusion, control, and intimacy--constitute an optimal priority sequence for managing major family change stemming from life-cycle transitions and other stressful experiences. In the next section of the article, we compare the Family FIRO Model and other models of family change. Finally, we suggest that therapists can benefit from an explicit, clinical decision-making model for setting priorities in treatment: issues of inclusion take precedence over issues of control, which in turn take precedence over issues of intimacy.

  9. Changing patterns of malaria during 1996-2010 in an area of moderate transmission in Southern Senegal

    Directory of Open Access Journals (Sweden)

    Vaillant Michel T

    2011-07-01

    Full Text Available Abstract Background Malaria is reportedly receding in different epidemiological settings, but local long-term surveys are limited. At Mlomp dispensary in south-western Senegal, an area of moderate malaria transmission, year-round, clinically-suspected malaria was treated with monotherapy as per WHO and national policy in the 1990s. Since 2000, there has been a staggered deployment of artesunate-amodiaquine after parasitological confirmation; this was adopted nationally in 2006. Methods Data were extracted from clinic registers for the period between January 1996 and December 2010, analysed and modelled. Results Over the 15-year study period, the risk of malaria decreased about 32-times (from 0.4 to 0.012 episodes person-year, while anti-malarial treatments decreased 13-times (from 0.9 to 0.07 treatments person-year and consultations for fever decreased 3-times (from 1.8 to 0.6 visits person-year. This was paralleled by changes in the age profile of malaria patients so that the risk of malaria is now almost uniformly distributed throughout life, while in the past malaria used to concern more children below 16 years of age. Conclusions This study provides direct evidence of malaria risk receding between 1996-2010 and becoming equal throughout life where transmission used to be moderate. Infection rates are no longer enough to sustain immunity. Temporally, this coincides with deploying artemisinin combinations on parasitological confirmation, but other contributing causes are unclear.

  10. A large proportion of asymptomatic Plasmodium infections with low and sub-microscopic parasite densities in the low transmission setting of Temotu Province, Solomon Islands: challenges for malaria diagnostics in an elimination setting

    Directory of Open Access Journals (Sweden)

    Harris Ivor

    2010-09-01

    Full Text Available Abstract Background Many countries are scaling up malaria interventions towards elimination. This transition changes demands on malaria diagnostics from diagnosing ill patients to detecting parasites in all carriers including asymptomatic infections and infections with low parasite densities. Detection methods suitable to local malaria epidemiology must be selected prior to transitioning a malaria control programme to elimination. A baseline malaria survey conducted in Temotu Province, Solomon Islands in late 2008, as the first step in a provincial malaria elimination programme, provided malaria epidemiology data and an opportunity to assess how well different diagnostic methods performed in this setting. Methods During the survey, 9,491 blood samples were collected and examined by microscopy for Plasmodium species and density, with a subset also examined by polymerase chain reaction (PCR and rapid diagnostic tests (RDTs. The performances of these diagnostic methods were compared. Results A total of 256 samples were positive by microscopy, giving a point prevalence of 2.7%. The species distribution was 17.5% Plasmodium falciparum and 82.4% Plasmodium vivax. In this low transmission setting, only 17.8% of the P. falciparum and 2.9% of P. vivax infected subjects were febrile (≥38°C at the time of the survey. A significant proportion of infections detected by microscopy, 40% and 65.6% for P. falciparum and P. vivax respectively, had parasite density below 100/μL. There was an age correlation for the proportion of parasite density below 100/μL for P. vivax infections, but not for P. falciparum infections. PCR detected substantially more infections than microscopy (point prevalence of 8.71%, indicating a large number of subjects had sub-microscopic parasitemia. The concordance between PCR and microscopy in detecting single species was greater for P. vivax (135/162 compared to P. falciparum (36/118. The malaria RDT detected the 12 microscopy and

  11. Social transmission of avoidance behavior under situational change in learned and unlearned rats.

    Directory of Open Access Journals (Sweden)

    Akira Masuda

    Full Text Available BACKGROUND: Rats receive information from other conspecifics by observation or other types of social interaction. Such social interaction may contribute to the effective adaptation to changes of environment such as situational switching. Learning to avoid dangerous places or objects rapidly occurs with even a single conditioning session, and the conditioned memory tends to be sustained over long periods. The avoidance is important for adaptation, but the details of the conditions under which the social transmission of avoidance is formed are unknown. We demonstrate that the previous experience of avoidance learning is important for the formation of behaviors for social transmission of avoidance and that the experienced rats adapt to a change of situation determined by the presence or absence of aversive stimuli. We systematically investigated social influence on avoidance behavior using a passive avoidance test in a light/dark two-compartment apparatus. METHODOLOGY/PRINCIPAL FINDINGS: Rats were divided into two groups, one receiving foot shocks and another with no aversive experience in a dark compartment. Experienced and inexperienced rats were further divided into subjects and partners. In Experiment 1, each subject experienced (1 interaction with an experienced partner, (2 interaction with an inexperienced partner, or (3 no interaction. In Experiment 2, each subject experienced interaction with a partner that received a shock. The entering latency to a light compartment was measured. The avoidance behavior of experienced rats was inhibited by interaction with inexperienced or experienced partners in a safely-changed situation. The avoidance of experienced rats was reinstated in a dangerously-changed situation by interaction with shocked rats. In contrast, the inexperienced rats were not affected by any social circumstances. CONCLUSIONS/SIGNIFICANCE: These results suggest that transmitted information among rats can be updated under a

  12. Modelling the effect of changes in vaccine effectiveness and transmission contact rates on pertussis epidemiology.

    Science.gov (United States)

    Pesco, P; Bergero, P; Fabricius, G; Hozbor, D

    2014-06-01

    The incidence of the highly infectious respiratory disease named pertussis or whooping cough has been increasing for the past two decades in different countries, as in much of the highly vaccinated world. A decrease in vaccine effectiveness over time, especially when acellular vaccines were used for primary doses and boosters, and pathogen adaptation to the immunity conferred by vaccines have been proposed as possible causes of the resurgence. The contributions of these factors are not expected to be the same in different communities, and this could lead to different epidemiological trends. In fact, differences in the magnitude and dynamics of pertussis outbreaks as well as in the distribution of notified cases by age have been reported in various regions. Using an age-structured mathematical model designed by us, we evaluated how the changes in some of the parameters that could be related to the above proposed causes of disease resurgence - vaccine effectiveness and effective transmission rates - may impact on pertussis transmission. When a linear decrease in vaccine effectiveness (VE) was assayed, a sustained increase in pertussis incidence was detected mainly in infants and children. On the other hand, when changes in effective transmission rates (βij) were made, a dynamic effect evidenced by the presence of large peaks followed by deep valleys was detected. In this case, greater incidence in adolescents than in children was observed. These different trends in the disease dynamics due to modifications in VE or βij were verified in 18 possible scenarios that represent different epidemiological situations. Interestingly we found that both incidence trends produced by the model and their age distribution resemble the profiles obtained from data reported in several regions. The implications of these correlations are discussed.

  13. Assessing the Role of Climate Change in Malaria Transmission in Africa

    Directory of Open Access Journals (Sweden)

    E. T. Ngarakana-Gwasira

    2016-01-01

    Full Text Available The sensitivity of vector borne diseases like malaria to climate continues to raise considerable concern over the implications of climate change on future disease dynamics. The problem of malaria vectors shifting from their traditional locations to invade new zones is of important concern. A mathematical model incorporating rainfall and temperature is constructed to study the transmission dynamics of malaria. The reproduction number obtained is applied to gridded temperature and rainfall datasets for baseline climate and future climate with aid of GIS. As a result of climate change, malaria burden is likely to increase in the tropics, the highland regions, and East Africa and along the northern limit of falciparum malaria. Falciparum malaria will spread into the African highlands; however it is likely to die out at the southern limit of the disease.

  14. Estimating Plasmodium falciparum transmission rates in low-endemic settings using a combination of community prevalence and health facility data.

    Science.gov (United States)

    Yukich, Joshua; Briët, Olivier; Bretscher, Michael T; Bennett, Adam; Lemma, Seblewengel; Berhane, Yemane; Eisele, Thomas P; Keating, Joseph; Smith, Thomas

    2012-01-01

    As some malaria control programs shift focus from disease control to transmission reduction, there is a need for transmission data to monitor progress. At lower levels of transmission, it becomes increasingly more difficult to measure precisely, for example through entomological studies. Many programs conduct regular cross sectional parasite prevalence surveys, and have access to malaria treatment data routinely collected by ministries of health, often in health management information systems. However, by themselves, these data are poor measures of transmission. In this paper, we propose an approach for combining annual parasite incidence and treatment data with cross-sectional parasite prevalence and treatment seeking survey data to estimate the incidence of new infections in the human population, also known as the force of infection. The approach is based on extension of a reversible catalytic model. The accuracy of the estimates from this model appears to be highly dependent on levels of detectability and treatment in the community, indicating the importance of information on private sector treatment seeking and access to effective and appropriate treatment.

  15. Political science. When contact changes minds: an experiment on transmission of support for gay equality.

    Science.gov (United States)

    LaCour, Michael J; Green, Donald P

    2014-12-12

    Can a single conversation change minds on divisive social issues, such as same-sex marriage? A randomized placebo-controlled trial assessed whether gay (n = 22) or straight (n = 19) messengers were effective at encouraging voters (n = 972) to support same-sex marriage and whether attitude change persisted and spread to others in voters' social networks. The results, measured by an unrelated panel survey, show that both gay and straight canvassers produced large effects initially, but only gay canvassers' effects persisted in 3-week, 6-week, and 9-month follow-ups. We also find strong evidence of within-household transmission of opinion change, but only in the wake of conversations with gay canvassers. Contact with gay canvassers further caused substantial change in the ratings of gay men and lesbians more generally. These large, persistent, and contagious effects were confirmed by a follow-up experiment. Contact with minorities coupled with discussion of issues pertinent to them is capable of producing a cascade of opinion change.

  16. Correlative transmission electron microscopy and electrical properties study of switchable phase-change random access memory line cells

    Energy Technology Data Exchange (ETDEWEB)

    Oosthoek, J. L. M.; Kooi, B. J., E-mail: B.J.Kooi@rug.nl [Zernike Institute for Advanced Materials and Materials innovation institute M2i, University of Groningen, Nijenborgh 4, 9747 AG Groningen (Netherlands); Voogt, F. C.; Attenborough, K. [NXP, Gerstweg 2, 6534 AE Nijmegen (Netherlands); Verheijen, M. A. [Department of Applied Physics, Eindhoven University of Technology, NL-5600 MB Eindhoven (Netherlands); Philips Innovation Services Eindhoven, High Tech Campus 11, NL-5656 AE Eindhoven (Netherlands); Hurkx, G. A. M. [NXP Semiconductors, High Tech Campus 60, 5656 AE Eindhoven (Netherlands); Gravesteijn, D. J. [NXP Semiconductors, Kapeldreef 75, B 3001 Leuven (Belgium)

    2015-02-14

    Phase-change memory line cells, where the active material has a thickness of 15 nm, were prepared for transmission electron microscopy (TEM) observation such that they still could be switched and characterized electrically after the preparation. The result of these observations in comparison with detailed electrical characterization showed (i) normal behavior for relatively long amorphous marks, resulting in a hyperbolic dependence between SET resistance and SET current, indicating a switching mechanism based on initially long and thin nanoscale crystalline filaments which thicken gradually, and (ii) anomalous behavior, which holds for relatively short amorphous marks, where initially directly a massive crystalline filament is formed that consumes most of the width of the amorphous mark only leaving minor residual amorphous regions at its edges. The present results demonstrate that even in (purposely) thick TEM samples, the TEM sample preparation hampers the probability to observe normal behavior and it can be debated whether it is possible to produce electrically switchable TEM specimen in which the memory cells behave the same as in their original bulk embedded state.

  17. Rates of cultural change and patterns of cultural accumulation in stochastic models of social transmission.

    Science.gov (United States)

    Aoki, Kenichi; Lehmann, Laurent; Feldman, Marcus W

    2011-06-01

    Cultural variation in a population is affected by the rate of occurrence of cultural innovations, whether such innovations are preferred or eschewed, how they are transmitted between individuals in the population, and the size of the population. An innovation, such as a modification in an attribute of a handaxe, may be lost or may become a property of all handaxes, which we call "fixation of the innovation." Alternatively, several innovations may attain appreciable frequencies, in which case properties of the frequency distribution-for example, of handaxe measurements-is important. Here we apply the Moran model from the stochastic theory of population genetics to study the evolution of cultural innovations. We obtain the probability that an initially rare innovation becomes fixed, and the expected time this takes. When variation in cultural traits is due to recurrent innovation, copy error, and sampling from generation to generation, we describe properties of this variation, such as the level of heterogeneity expected in the population. For all of these, we determine the effect of the mode of social transmission: conformist, where there is a tendency for each naïve newborn to copy the most popular variant; pro-novelty bias, where the newborn prefers a specific variant if it exists among those it samples; one-to-many transmission, where the variant one individual carries is copied by all newborns while that individual remains alive. We compare our findings with those predicted by prevailing theories for rates of cultural change and the distribution of cultural variation.

  18. Priority interventions to reduce HIV transmission in sex work settings in sub-Saharan Africa and delivery of these services

    NARCIS (Netherlands)

    M. Chersich (Matthew); S. Luchters (Stanley); I. Ntaganira (Innocent); A. Gerbase (Antonio); Y-R. Lo (Ying-Ru); F. Scorgie (Fiona); R. Steen (Richard)

    2012-01-01

    textabstractIntroduction: Virtually no African country provides HIV prevention services in sex work settings with an adequate scale and intensity. Uncertainty remains about the optimal set of interventions and mode of delivery. Methods: We systematically reviewed studies reporting interventions for

  19. Light and transmission electron microscopical changes associated with Leiurus quinqestriatus venom in rabbits

    Directory of Open Access Journals (Sweden)

    Salah H. Afifi

    2016-03-01

    Full Text Available Thirty California female rabbits were obtained from the Animal Care Center, College of Agriculture, South Valley University and acclimated to laboratory conditions for one week. The Leiurus quinquestriatus (LQ venom was collected from mature scorpions by electrical stimulation of the telson. A single dose of crude venom of 0.4 ml/kg (diluted in normal saline with a ratio of 1:1 was injected into a peripheral ear vein. The lungs, brains, hearts, kidneys, were sampled and fixed in 10% formalin from rabbits sacrificed at zero, 30 minutes, 1hr, and 4hrs, post-envenomation (three animals at each sacrifice. Respiratory distress and neurological manifestations were the main clinical signs. Congestion of the lungs was started at one hour postenvenomation. Vascular changes including hyperemia and hemorrhage were also observed till 24 hours post-envenomation. The main histopathological changes of the lungs were edema, hemorrhage, emphysema, and eosinophilic bronchitis. Transmission electron microscopy revealed several eosinophils with abundant granules and breakdown of their membranes suggesting degranulation. The cerebrum showed malacia and edema. Myocardial damage expressed by focal area of myolysis at half-hour post-envenomation and interstitial edema by at 1, and 4 hour post-envenomation was also evident. In conclusion, scorpion venom induced consistent and relevant histopathological changes in all examined organs.

  20. Transmission Dynamics of Extended-Spectrum β-lactamase–Producing Enterobacteriaceae in the Tertiary Care Hospital and the Household Setting

    OpenAIRE

    2012-01-01

    Background . Studies about transmission rates of extended-spectrum β-lactamase (ESBL)–producing Enterobacteriaceae in hospitals and households are scarce. Methods . Eighty-two index patients with new carriage of ESBL-producing Escherichia coli (ESBL-Ec; n = 72) or ESBL-producing Klebsiella pneumoniae (ESBL-Kp; n = 10) and their hospital (n = 112) and household (n = 96) contacts were studied prospectively from May 2008 through September 2010. Isolates were phenotypically and molecularly charac...

  1. REACH, non-testing approaches and the urgent need for a change in mind set

    NARCIS (Netherlands)

    Schaafsma, G.; Kroese, E.D.; Tielemans, E.L.J.P.; Sandt, J.J.M. van de; Leeuwen, C.J. van

    2009-01-01

    The objectives of REACH cannot be achieved under the current risk assessment approach. A change in mind set among all the relevant stakeholders is needed: risk assessment should move away from a labor-intensive and animal-consuming approach to intelligent and pragmatic testing, by combining exposure

  2. Paradigms, Mental Models, and Mind-Sets: Triple Barriers to Transformational Change in School Systems

    Science.gov (United States)

    Duffy, Francis M.

    2014-01-01

    This article presents a simile for understanding the power of paradigms, mental models, and mind-sets as religion-like phenomena. The author clarifies the meaning of the three phenomena to help readers to see how the phenomena become significant sources of resistance to change. He concludes by outlining a paradigm-shifting process to assist…

  3. Chromatographic analysis of age-related changes in mucosal serotonin transmission in the murine distal ileum

    Directory of Open Access Journals (Sweden)

    Parmar Leena

    2012-04-01

    Full Text Available Abstract Background In the upper bowel, alterations in motility and absorption of key nutrients have been observed as part of the normal ageing process. Serotonin (5-HT is a key signalling molecule in the gastrointestinal tract and is known to influence motility, however little is known of how the ageing process alters 5-HT signalling processes in the bowel. Results An isocratic chromatographic method was able to detect all 5-HT precursors and metabolites. Using extracellular and intracellular sampling approaches, we were able to monitor all key parameters associated with the transmission process. There was no alteration in the levels of tryptophan and 5-HTP between 3 and 18 month old animals. There was a significant increase in the ratio of 5-HT:5-HTP and an increase in intracellular 5-HT between 3 and 18 month old animals suggesting an increase in 5-HT synthesis. There was also a significant increase in extracellular 5-HT with age, suggesting increased 5-HT release. There was an age-related decrease in the ratio of intracellular 5-HIAA:extracellular 5-HT, whilst the amount of 5-HIAA did not change with age. In the presence of an increase in extracellular 5-HT, the lack of an age-related change in 5-HIAA is suggestive of a decrease in re-uptake via the serotonin transporter (SERT. Conclusions We have used intracellular and extracellular sampling to provide more insight into alterations in the neurotransmission process of 5-HT during normal ageing. We observed elevated 5-HT synthesis and release and a possible decrease in the activity of SERT. Taken together these changes lead to increased 5-HT availability and may alter motility function and could lead to the changes in adsorption observed in the elderly.

  4. Monitoring of environmental change in Dzungar basin by the analysis of multi temporal satellite data sets

    Science.gov (United States)

    Nakayama, Y.; Yanagi, T.; Nishimura, J.

    In recent 40-50 years, rapid environmental changes are shown in the arid and semi-arid regions of the inland areas in each continent. The environment change situation is especially remarkable at closed lakes and their vicinity of the Asian continent inland. This study aimed to investigate the environmental change and its cause in Dzungar basin of the central Asia through the analysis of multi-temporal satellite data sets. The multi temporal and multi stage satellite data sets were firstly created by using high spatial resolution satellite data such as LANDSAT/MSS TM, Terra/ASTER, and JERS-1/OPS, and wide observation satellite data such as NOAA/AVHRR and Terra/MODIS. Next, the fluctuations of the past about 50 years in water area of lakes were investigated in detail by analyzing the data sets, and also changes in the irrigated agricultural lands along the inflow rivers, and the snow and glacier covering the mountainous district were investigated. Finally, hydrological change situation and its cause in the object area were examined by comparing the analyzed results with meteorological data and auxiliary sources. The results of this study are summarized as follows; Most of closed lakes in Dzungar basin have shown the rapid shrinkages in the past about 50 years. However, it changed into the remarkable expansion of the water area since 2001. According to the analysis results of changes in the irrigated agricultural lands, snow and glacier extents, it was shown that the influence of human activities such as development of irrigation lands was bigger than the influence of the nature fluctuation based on the global warming as a cause of the change in closed lakes.

  5. SIMULATION OF VARIOUS QoS PARAMETERS IN A HIGH DENSITY MANET SET-UP USING AODV nthBR PROTOCOL FOR MULTIMEDIA TRANSMISSION, DATA TRANSMISSION AND UNDER CONGESTION SCENARIO

    Directory of Open Access Journals (Sweden)

    Meena Rao

    2015-09-01

    Full Text Available Mobile ad hoc networks (MANETs are a setup of several independent nodes that are capable of transmitting any kind of data by themselves. In MANETs, the node themselves act as routers and the setup can either be single hop or multihop depending on the application. These devices have wide and varied applications; like in military deployment, for network set up in meetings, electronic classrooms etc. As the applications and use of MANETs has increased, it has also become imminent for MANETs to support multimedia transmission, high quality data transmission and also to work efficiently in a congestion scenario. To support these parameters it is necessary to have a robust routing protocol that provides good Quality of Service (QoS parameters under different conditions. In this paper the authors simulate transmission of multimedia traffic with AODV nthBR routing protocol for a high density MANET setup. AODV nthBR routing protocol is also simulated for a congestion scenario and the results are then compared with the existing routing protocols.

  6. Health Care Workers and Researchers Traveling to Developing-World Clinical Settings: Disease Transmission Risk and Mitigation

    Science.gov (United States)

    2010-01-01

    specific health care-related risks (needlestick, hemorrhagic fever viruses, severe viral respiratory disease, and tuberculosis ), with suggestions...specific Japanese encephalitis virus (parts of South and Southeast Asia) Meningococcal ( meningitis belt of Africa) Yellow fever (parts of Africa...indicated in certain settings, such as direct contact with sources of avian influenza [39]. DRUG-RESISTANT TUBERCULOSIS In general, tuberculosis is a

  7. An update: choice architecture as a means to change eating behaviour in self-service settings

    DEFF Research Database (Denmark)

    Skov, Laurits Rohden; Perez-Cueto, Armando

    2014-01-01

    Objective: The primary objective of this review was to update the current evidence-base for the use of choice architecture as a means to change eating behaviour in self-service eating settings, hence potentially reducing energy intake. Methodology: 12 databases were searched systematically...... food choices. The majority of studies were of very weak quality and future research should emphasize a real-life setting and compare their results with the effect of other more well-established interventions on food behaviour in self-service eating settings. Key findings: An increasing interest...... in the topic of choice architecture and nudging has increased the scientific output since the last review. There is a clear limitation in the lack of a clear definitions and theoretical foundation....

  8. The use of individualized goal setting to facilitate behavior change in women with multiple sclerosis.

    Science.gov (United States)

    Stuifbergen, Alexa K; Becker, Heather; Timmerman, Gayle M; Kullberg, Vicki

    2003-04-01

    Setting goals is a useful strategy for changing behavior. The purpose of this study was to examine the effectiveness of a wellness intervention for women with multiple sclerosis (MS) on achieving health-related goals set individually by each participant in the experimental group (N = 57) using goal attainment scaling. The two-phase intervention included lifestyle-change classes over 8 weeks, then telephone follow-up over 3 months. Participants were followed over an 8-month period. Goal achievement was assessed at baseline, 2 months (following class), 3 1/2 months (6 weeks after class), 5 months (following 3 months of telephone follow-up), and at 8 months. The majority of the women met or exceeded all their individualized goals for changing behavior at the 6-week postclass assessment. Achievement and maintenance of individual goals remained high (59%-84%) over the 5 months after class follow-ups. These data support the positive effects of wellness interventions for helping women with MS to meet their own individualized health goals. Setting goals with incremental steps helped participants to articulate their individual goals and monitor achievement over time.

  9. How do sharp transmission boundaries change the effective radius of a transiting exoplanet?

    Science.gov (United States)

    Betremieux, Yan; Swain, Mark R.

    2016-10-01

    Most radiative transfer codes for exoplanet transmission spectroscopy either use or are validated against the formalism of Lecavelier des Etangs et al. (2008). Although extremely useful to understand what shapes transmission spectra, this formalism does not consider the effects of sharp boundaries below which an exoplanet's limb transmission suddenly decreases. However, with recent advances on the effects of refraction in transmission spectroscopy (Bétrémieux & Kaltenegger 2014, Bétrémieux 2016), it turns out that all exoplanets possess one such boundary in the form of either a surface, optically-thick clouds, or in the form of a refractive boundary. We have deriveda first-order analytical expression for an exoplanet's effective radius, which can be used to further validate or improve radiative transfer codes, which accounts for the presence of these boundaries, and discuss their effects on exoplanetary transmission spectra.

  10. No major change in vCJD agent strain after secondary transmission via blood transfusion.

    Directory of Open Access Journals (Sweden)

    Matthew T Bishop

    Full Text Available BACKGROUND: The identification of transmission of variant Creutzfeldt-Jakob disease (vCJD by blood transfusion has prompted investigation to establish whether there has been any alteration in the vCJD agent following this route of secondary transmission. Any increase in virulence or host adaptation would require a reassessment of the risk analyses relating to the possibility of a significant secondary outbreak of vCJD. Since there are likely to be carriers of the vCJD agent in the general population, there is a potential for further infection by routes such as blood transfusion or contaminated surgical instruments. METHODOLOGY: We inoculated both wild-type and transgenic mice with material from the first case of transfusion associated vCJD infection. PRINCIPAL FINDINGS: The strain transmission properties of blood transfusion associated vCJD infection show remarkable similarities to the strain of vCJD associated with transmission from bovine spongiform encephalopathy (BSE. CONCLUSIONS: Although it has been hypothesized that adaptation of the BSE agent through secondary passage in humans may result in a greater risk of onward transmission due to an increased virulence of the agent for humans, our data presented here in two murine models suggest no significant alterations to transmission efficiency of the agent following human-to-human transmission of vCJD.

  11. Intrapulpal Thermal Changes during Setting Reaction of Glass Carbomer® Using Thermocure Lamp

    Science.gov (United States)

    Tosun, Gül

    2016-01-01

    Objectives. To measure the temperature increase induced during thermocure lamp setting reaction of glass carbomer and to compare it with those induced by visible light curing of a resin-modified glass ionomer and a polyacid-modified composite resin in primary and permanent teeth. Materials and Methods. Nonretentive class I cavities were prepared in extracted primary and permanent molars. Glass carbomer (GC) was placed in the cavity and set at 60°C for 60 sn using a special thermocure lamp. Resin-modified glass ionomer (RMGIC) and polyacid-modified composite resin (PMCR) were placed in the cavities and polymerized with an LED curing unit. Temperature increases during setting reactions were measured with a J-type thermocouple wire connected to a data logger. Data were examined using two-way analysis of variance and Tukey's honestly significant difference tests. Results. The use of GC resulted in temperature changes of 5.17 ± 0.92°C and 5.32 ± 0.90°C in primary and permanent teeth, respectively (p > 0.05). Temperature increases were greatest in the GC group, differing significantly from those in the PMCR group (p < 0.05). Conclusion. Temperature increases during polymerization and setting reactions of the materials were below the critical value in all groups. No difference was observed between primary and permanent teeth, regardless of the material used. PMID:28097136

  12. Testing Allele Transmission of an SNP Set Using a Family-Based Generalized Genetic Random Field Method.

    Science.gov (United States)

    Li, Ming; Li, Jingyun; He, Zihuai; Lu, Qing; Witte, John S; Macleod, Stewart L; Hobbs, Charlotte A; Cleves, Mario A

    2016-05-01

    Family-based association studies are commonly used in genetic research because they can be robust to population stratification (PS). Recent advances in high-throughput genotyping technologies have produced a massive amount of genomic data in family-based studies. However, current family-based association tests are mainly focused on evaluating individual variants one at a time. In this article, we introduce a family-based generalized genetic random field (FB-GGRF) method to test the joint association between a set of autosomal SNPs (i.e., single-nucleotide polymorphisms) and disease phenotypes. The proposed method is a natural extension of a recently developed GGRF method for population-based case-control studies. It models offspring genotypes conditional on parental genotypes, and, thus, is robust to PS. Through simulations, we presented that under various disease scenarios the FB-GGRF has improved power over a commonly used family-based sequence kernel association test (FB-SKAT). Further, similar to GGRF, the proposed FB-GGRF method is asymptotically well-behaved, and does not require empirical adjustment of the type I error rates. We illustrate the proposed method using a study of congenital heart defects with family trios from the National Birth Defects Prevention Study (NBDPS).

  13. Influence of Weaving Loom Setting Parameters on Changes of Woven Fabric Structure and Mechanical Properties

    Directory of Open Access Journals (Sweden)

    Aušra ADOMAITIENĖ

    2011-11-01

    Full Text Available During the manufacturing of fabric of different raw material there was noticed, that after removing the fabric from weaving loom and after stabilization of fabric structure, the changes of parameters of fabric structure are not regular. During this investigation it was analysed, how weaving loom technological parameters (heald cross moment and initial tension of warp should be chosen and how to predict the changes of fabric structure parameters and its mechanical properties. The dependencies of changes of half-wool fabric structure parameters (weft setting, fabric thickness and projections of fabric cross-section and mechanical properties (breaking force, elongation at break, static friction force and static friction coefficient on weaving loom setting parameters (heald cross moment and initial warp tension were analysed. The orthogonal Box plan of two factors was used, the 3-D dependencies were drawn, and empirical equations of these dependencies were established.http://dx.doi.org/10.5755/j01.ms.17.4.780

  14. Climate change impacts on West Nile virus transmission in a global context

    OpenAIRE

    Paz, Shlomit

    2015-01-01

    West Nile virus (WNV), the most widely distributed virus of the encephalitic flaviviruses, is a vector-borne pathogen of global importance. The transmission cycle exists in rural and urban areas where the virus infects birds, humans, horses and other mammals. Multiple factors impact the transmission and distribution of WNV, related to the dynamics and interactions between pathogen, vector, vertebrate hosts and environment. Hence, among other drivers, weather conditions have direct and indirec...

  15. Cerebral Blood Flow Dynamics and Head-of-Bed Changes in the Setting of Subarachnoid Hemorrhage

    Directory of Open Access Journals (Sweden)

    David K. Kung

    2013-01-01

    Full Text Available Head-of-bed (HOB elevation is usually restricted in patients with aneurysmal subarachnoid hemorrhage (SAH. The goal of this study is to correlate HOB changes ( and with cerebral blood flow using transcranial Doppler (TCD and thermal diffusion probe in SAH patients. Thirteen patients with SAH were prospectively enrolled in the study. Eight patients underwent placement of a thermal diffusion probe for regional CBF measurement. CBF values were measured with the patients in flat ( and upright sitting positions ( at days 3, 7, and 10. The average increase in blood flow velocity when changing HOB from to was 7.8% on day 3, 0.1% on day 7, and 13.1% on day 10. The middle cerebral artery had the least changes in velocity. The average regional CBF measurement was 22.7 ± 0.3 mL/100 g/min in the supine position and 23.6 ± 9.1 mg/100 g/min in the sitting position. The changes were not statistically significant. None of the patients developed clinical cerebral vasospasm. Changing HOB position in the setting of SAH did not significantly affect cerebral or regional blood flow. These data suggest that early mobilization should be considered given the detrimental effects of prolonged bed rest.

  16. Numerical Simulation of Two-phase flow with Phase Change Using the Level-set Method

    Science.gov (United States)

    Li, Hongying; Lou, Jing; Pan, Lunsheng; Yap, Yitfatt

    2016-11-01

    Multiphase flow with phase change is widely encountered in many engineering applications. A distinct feature involves in these applications is the phase transition from one phase to another due to the non-uniform temperature distribution. Such kind of process generally releases or absorbs large amount of energy with mass transfer happened simultaneously. It demands great cautions occasionally such as the high pressure due to evaporation. This article presents a numerical model for simulation of two-fluid flow with phase change problem. In these two fluids, one of them changes its state due to phase change. Such a problem then involves two substances with three phases as well as two different interfaces, i.e. the interface between two substances and the interface of one substance between its two phases. Two level-set functions are used to capture the two interfaces in the current problem. The current model is validated against one-dimensional and two-dimensional liquid evaporation. With the code validated, it is applied to different phase change problems including (1) a falling evaporating droplet and the rising of one bubble and (2) two-fluid stratified flow with solidification of one fluid. Comparisons on the bubble and droplet topologies, flow and temperature fields are made for the first case between the falling evaporating droplet and the falling droplet without evaporation. For the second demonstration case, the effect of the superheated temperature on the solidification process is investigated.

  17. Tracing Mycobacterium tuberculosis transmission by whole genome sequencing in a high incidence setting: a retrospective population-based study in East Greenland

    Science.gov (United States)

    Bjorn-Mortensen, K.; Soborg, B.; Koch, A.; Ladefoged, K.; Merker, M.; Lillebaek, T.; Andersen, A. B.; Niemann, S.; Kohl, T. A.

    2016-01-01

    In East Greenland, a dramatic increase of tuberculosis (TB) incidence has been observed in recent years. Classical genotyping suggests a genetically similar Mycobacterium tuberculosis (Mtb) strain population as cause, however, precise transmission patterns are unclear. We performed whole genome sequencing (WGS) of Mtb isolates from 98% of culture-positive TB cases through 21 years (n = 182) which revealed four genomic clusters of the Euro-American lineage (mainly sub-lineage 4.8 (n = 134)). The time to the most recent common ancestor of lineage 4.8 strains was found to be 100 years. This sub-lineage further diversified in the 1970s, and massively expanded in the 1990s, a period of lowered TB awareness in Greenland. Despite the low genetic strain diversity, WGS data revealed several recent short-term transmission events in line with the increasing incidence in the region. Thus, the isolated setting and the uniformity of circulating Mtb strains indicated that the majority of East Greenlandic TB cases originated from one or few strains introduced within the last century. Thereby, the study shows the consequences of even short interruptions in TB control efforts in previously TB high incidence areas and demonstrates the potential role of WGS in detecting ongoing micro epidemics, thus guiding public health efforts in the future. PMID:27615360

  18. Changes in setting time of alginate impression material with different water temperature

    Directory of Open Access Journals (Sweden)

    Decky J. Indrani

    2013-03-01

    Full Text Available Background: Previous studies showed that setting process of alginates can be influenced by temperature. Purpose: To determine the changes in setting time due to differences in water temperature and to determine the correlation between water temperature and the setting time. Methods: Seven groups of dough alginate were prepared by mixing alginate powder and water, each using a temperature between 13° C–28° C with a interval of 2.5° C. A sample mold (Θ = 30 mm, t = 16 mm was placed on a flat plate and filled with doug alginate. Immediately the flat end of a polished acrylic rod was placed in contact with the surface of dough alginate. Setting time of alginat was measured from the starting of the mix to the time when the alginate does not adhere to the end of the rod. Setting time alginate data were analyzed using one way ANOVA, LSD and Pearson. Results: Setting time of alginate with water temperature between 13° C–28° C were 87 to 119.4 seconds and were significantly different (p < 0.01. The setting time between group were also significantly different (p<0.01. There was an inverse correlation between water temperature and the setting time (r = -0.968. Conclusion: Water temperature between 13° C–28°C with a difference of 2.5° C produced significant differences in alginate setting time; the lower the water temperature being used the longer the setting time was produced.Latar belakang: Penelitian-penelitian sebelumnya menunjukkan bahwa proses pengerasan alginat dapat dipengaruhi oleh suhu. Tujuan: Mengetahui perubahan waktu pengerasan alginat akibat perbedaan suhu air serta mengetahui hubungan antara suhu air dan waktu pengerasan. Metode: Tujuh kelompok adonan alginat yang dipersiapkan dengan mencampur bubuk alginat dan air, masingmasing menggunakan suhu antara 13°C–28° C dengan interval 2,5° C. Pengukuran waktu pengerasan alginat dilakukan sesuai dengan spesifikasi ADA no.18. Sebuah cetakan sampel terbuat dari pralon berbentuk

  19. Sero-epidemiological evaluation of changes in Plasmodium falciparum and Plasmodium vivax transmission patterns over the rainy season in Cambodia

    Directory of Open Access Journals (Sweden)

    Cook Jackie

    2012-03-01

    Full Text Available Abstract Background In Cambodia, malaria transmission is low and most cases occur in forested areas. Sero-epidemiological techniques can be used to identify both areas of ongoing transmission and high-risk groups to be targeted by control interventions. This study utilizes repeated cross-sectional data to assess the risk of being malaria sero-positive at two consecutive time points during the rainy season and investigates who is most likely to sero-convert over the transmission season. Methods In 2005, two cross-sectional surveys, one in the middle and the other at the end of the malaria transmission season, were carried out in two ecologically distinct regions in Cambodia. Parasitological and serological data were collected in four districts. Antibodies to Plasmodium falciparum Glutamate Rich Protein (GLURP and Plasmodium vivax Merozoite Surface Protein-119 (MSP-119 were detected using Enzyme Linked Immunosorbent Assay (ELISA. The force of infection was estimated using a simple catalytic model fitted using maximum likelihood methods. Risks for sero-converting during the rainy season were analysed using the Classification and Regression Tree (CART method. Results A total of 804 individuals participating in both surveys were analysed. The overall parasite prevalence was low (4.6% and 2.0% for P. falciparum and 7.9% and 6.0% for P. vivax in August and November respectively. P. falciparum force of infection was higher in the eastern region and increased between August and November, whilst P. vivax force of infection was higher in the western region and remained similar in both surveys. In the western region, malaria transmission changed very little across the season (for both species. CART analysis for P. falciparum in the east highlighted age, ethnicity, village of residence and forest work as important predictors for malaria exposure during the rainy season. Adults were more likely to increase their antibody responses to P. falciparum during the

  20. The changing global distribution and prevalence of canine transmissible venereal tumour

    Science.gov (United States)

    2014-01-01

    Background The canine transmissible venereal tumour (CTVT) is a contagious cancer that is naturally transmitted between dogs by the allogeneic transfer of living cancer cells during coitus. CTVT first arose several thousand years ago and has been reported in dog populations worldwide; however, its precise distribution patterns and prevalence remain unclear. Results We analysed historical literature and obtained CTVT prevalence information from 645 veterinarians and animal health workers in 109 countries in order to estimate CTVT’s former and current global distribution and prevalence. This analysis confirmed that CTVT is endemic in at least 90 countries worldwide across all inhabited continents. CTVT is estimated to be present at a prevalence of one percent or more in dogs in at least 13 countries in South and Central America as well as in at least 11 countries in Africa and 8 countries in Asia. In the United States and Australia, CTVT was reported to be endemic only in remote indigenous communities. Comparison of current and historical reports of CTVT indicated that its prevalence has declined in Northern Europe, possibly due to changes in dog control laws during the nineteenth and twentieth centuries. Analysis of factors influencing CTVT prevalence showed that presence of free-roaming dogs was associated with increased CTVT prevalence, while dog spaying and neutering were associated with reduced CTVT prevalence. Our analysis indicated no gender bias for CTVT and we found no evidence that animals with CTVT frequently harbour concurrent infectious diseases. Vincristine was widely reported to be the most effective therapy for CTVT. Conclusions Our results provide a survey of the current global distribution of CTVT, confirming that CTVT is endemic in at least 90 countries worldwide. Additionally, our analysis highlights factors that continue to modify CTVT’s prevalence around the world and implicates free-roaming dogs as a reservoir for the disease. Our analysis

  1. Minimizing the Risk of Disease Transmission in Emergency Settings: Novel In Situ Physico-Chemical Disinfection of Pathogen-Laden Hospital Wastewaters.

    Directory of Open Access Journals (Sweden)

    Emanuele Sozzi

    Full Text Available The operation of a health care facility, such as a cholera or Ebola treatment center in an emergency setting, results in the production of pathogen-laden wastewaters that may potentially lead to onward transmission of the disease. The research presented here evaluated the design and operation of a novel treatment system, successfully used by Médecins Sans Frontières in Haiti to disinfect CTC wastewaters in situ, eliminating the need for road haulage and disposal of the waste to a poorly-managed hazardous waste facility, thereby providing an effective barrier to disease transmission through a novel but simple sanitary intervention. The physico-chemical protocols eventually successfully treated over 600 m3 of wastewater, achieving coagulation/flocculation and disinfection by exposure to high pH (Protocol A and low pH (Protocol B environments, using thermotolerant coliforms as a disinfection efficacy index. In Protocol A, the addition of hydrated lime resulted in wastewater disinfection and coagulation/flocculation of suspended solids. In Protocol B, disinfection was achieved by the addition of hydrochloric acid, followed by pH neutralization and coagulation/flocculation of suspended solids using aluminum sulfate. Removal rates achieved were: COD >99%; suspended solids >90%; turbidity >90% and thermotolerant coliforms >99.9%. The proposed approach is the first known successful attempt to disinfect wastewater in a disease outbreak setting without resorting to the alternative, untested, approach of 'super chlorination' which, it has been suggested, may not consistently achieve adequate disinfection. A basic analysis of costs demonstrated a significant saving in reagent costs compared with the less reliable approach of super-chlorination. The proposed approach to in situ sanitation in cholera treatment centers and other disease outbreak settings represents a timely response to a UN call for onsite disinfection of wastewaters generated in such

  2. Minimizing the Risk of Disease Transmission in Emergency Settings: Novel In Situ Physico-Chemical Disinfection of Pathogen-Laden Hospital Wastewaters.

    Science.gov (United States)

    Sozzi, Emanuele; Fabre, Kerline; Fesselet, Jean-François; Ebdon, James E; Taylor, Huw

    2015-01-01

    The operation of a health care facility, such as a cholera or Ebola treatment center in an emergency setting, results in the production of pathogen-laden wastewaters that may potentially lead to onward transmission of the disease. The research presented here evaluated the design and operation of a novel treatment system, successfully used by Médecins Sans Frontières in Haiti to disinfect CTC wastewaters in situ, eliminating the need for road haulage and disposal of the waste to a poorly-managed hazardous waste facility, thereby providing an effective barrier to disease transmission through a novel but simple sanitary intervention. The physico-chemical protocols eventually successfully treated over 600 m3 of wastewater, achieving coagulation/flocculation and disinfection by exposure to high pH (Protocol A) and low pH (Protocol B) environments, using thermotolerant coliforms as a disinfection efficacy index. In Protocol A, the addition of hydrated lime resulted in wastewater disinfection and coagulation/flocculation of suspended solids. In Protocol B, disinfection was achieved by the addition of hydrochloric acid, followed by pH neutralization and coagulation/flocculation of suspended solids using aluminum sulfate. Removal rates achieved were: COD >99%; suspended solids >90%; turbidity >90% and thermotolerant coliforms >99.9%. The proposed approach is the first known successful attempt to disinfect wastewater in a disease outbreak setting without resorting to the alternative, untested, approach of 'super chlorination' which, it has been suggested, may not consistently achieve adequate disinfection. A basic analysis of costs demonstrated a significant saving in reagent costs compared with the less reliable approach of super-chlorination. The proposed approach to in situ sanitation in cholera treatment centers and other disease outbreak settings represents a timely response to a UN call for onsite disinfection of wastewaters generated in such emergencies, and the

  3. Investigation of structural change of purple membrane in storage by transmission electron microscope and atomic force microscope

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The structural change of purple membrane during storage has been investigated by means of transmission electron microscope and atomic force microscope. It is found that many liposomes have spontaneously evolved from the purple membrane sheets isolated three years ago. The membrane proteins on the liposomes, bacteriorhodopsin, are still presented as trimers in 2-D hexagonal structure, which is the same as that in natural cell membrane. However, the cytoplasmic surface of purple membrane faced outside on the liposomes.

  4. [Transmission and circulation of tick borne pathogens (TBE and Lyme borreliosis) and the role of changing environment].

    Science.gov (United States)

    Zajkowska, Joanna M

    2010-01-01

    Ixodes ricinus is regarded as a species with great medical and veterinary meaning. Transmission of tick borne pathogens in mammals depends not only on systemic infection. Transmission of B. burgdorferi and tick-borne encephalitis virus in an infected organism differs, because of different location in tick, the differences in dissemination of the virus and bacteria (own motility) as well as mechanisms supporting bacterial infection. The mechanisms governing the transmission of these pathogens in nature have epidemiological importance and are essential in understanding the pathogenesis of diseases. The increase in the incidence of tick-borne encephalitis in recent years, is a marker of tick borne diseases. In the 90s, the number of cases among humans in many European countries remains at a higher level compared to the eighties. Similar observations consider to Lyme borreliosis. Natural environmental changes, mainly related to climate, as well as regional and local changes in distribution of the small rodents species, wild animals, anthropogenic factors (reforestation, drainage of swamps, increasing the reservoir of animals), and social change (increased human activities in forests, vaccinations) may have a significant impact on rates of tick-borne diseases.

  5. Choice architecture as a means to change eating behaviour in self-service settings

    DEFF Research Database (Denmark)

    Skov, Laurits Rohden; Lourenco, Sofia; Laub Hansen, Gitte

    2013-01-01

    food choice, whilst (ii) manipulating the plate and cutlery size has an inconclusive effect on consumption volume. Finally, (iii) assortment manipulation and (iv) payment option manipulation was associated with healthier food choices. The majority of studies were of very weak quality and future......Summary: The primary objective of this review was to investigate the current evidence-base for the use of choice architecture as a means to change eating behaviour in self-service eating settings, hence potentially reduce calorie intake. 12 databases were searched systematically for experimental...... studies with predefined choice architectural interventions in the period June 2011 – March 2012. The 12 included studies were grouped according to type of interventions and underwent a narrative synthesis. The evidence indicates that (i) health labelling at point-of-purchase is associated with healthier...

  6. From Fall to Spring, or Spring to Fall? Seasonal Cholera Transmission Cycles and Implications for Climate Change

    Science.gov (United States)

    Akanda, A. S.; Jutla, A. S.; Huq, A.; Colwell, R.; Islam, S.; WE Reason

    2010-12-01

    Cholera remains a major public health threat in many developing countries around the world. The striking seasonality and the annual recurrence of this infectious disease in endemic areas continues to be of considerable interest to scientists and public health workers. Despite major advances in the ecological, and microbiological understanding of Vibrio cholerae, the causative agent, the role of underlying macro-scale hydroclimatic processes in propagating the disease in different seasons and years is not well understood. The incidence of cholera in the Bengal Delta region, the ‘native homeland’ of cholera, shows distinct biannual peaks in the southern floodplains, as opposed to single annual peaks in coastal areas and the northern parts of Bangladesh, as well as other cholera-endemic regions in the world. A coupled analysis of the regional hydroclimate and cholera incidence reveals a strong association of the spatio-temporal variability of incidence peaks with seasonal processes and extreme events. At a seasonal scale, the cycles indicate a spring-fall transmission pattern, contrary to the prevalent notion of a fall-spring transmission cycle. We show that the asymmetric seasonal hydroclimatology affects regional cholera dynamics by providing a coastal growth environment for bacteria in spring, while propagating transmission to fall by flooding. This seasonal interpretation of the progression of cholera has important implications, for formulating effective cholera intervention and mitigation efforts through improved water management and understanding the impacts of changing climate patterns on seasonal cholera transmission. (Water Environental Research Education Actionable Solutions Network)

  7. Small Big Data: Using multiple data-sets to explore unfolding social and economic change

    Directory of Open Access Journals (Sweden)

    Emily Gray

    2015-06-01

    Full Text Available Bold approaches to data collection and large-scale quantitative advances have long been a preoccupation for social science researchers. In this commentary we further debate over the use of large-scale survey data and official statistics with ‘Big Data’ methodologists, and emphasise the ability of these resources to incorporate the essential social and cultural heredity that is intrinsic to the human sciences. In doing so, we introduce a series of new data-sets that integrate approximately 30 years of survey data on victimisation, fear of crime and disorder and social attitudes with indicators of socio-economic conditions and policy outcomes in Britain. The data-sets that we outline below do not conform to typical conceptions of ‘Big Data’. But, we would contend, they are ‘big’ in terms of the volume, variety and complexity of data which has been collated (and to which additional data can be linked and ‘big’ also in that they allow us to explore key questions pertaining to how social and economic policy change at the national level alters the attitudes and experiences of citizens. Importantly, they are also ‘small’ in the sense that the task of rendering the data usable, linking it and decoding it, required both manual processing and tacit knowledge of the context of the data and intentions of its creators.

  8. 输电网安全性需求评估指标集的构建%Evaluation Indices Set Construction of Security Requirement for Transmission Network

    Institute of Scientific and Technical Information of China (English)

    黄文英; 邓兆云; 邓勇; 何光宇; 陈睿; 刘铠诚

    2014-01-01

    The core requirement of transmission network enterprise lies in the safe operation of transmission network. Failure in satisfying this requirement will result in disastrous loss on economic and social benefits.Hence,transmission network is expected to possess the capability of enduring possible disturbances in order to ensure the normal operation of grid and equipment,as well as avoid the power transmission interruptions.Through the analysis on the requirement satisfaction of transmission system stakeholders,the overall status of transmission network operation can be evaluated.Based on the stochastic characteristics of transmission network operation,this paper used a risk assessment method to construct evaluation indices set for the security requirement,and proposed the calculation model and method of security risk assessment indicators.Compared with the traditional researches on grid security,a scenario analysis approach was introduced.In detail, breakdown or normal operation of certain components under certain specific operating modes was modeled as a scenario,and a probabilistic model for the scenario was constructed with taking into consideration a variety of random factors.All kinds of security problems were studied in the specific scenarios.The security of the situations could be evaluated comprehensively according to the safety criterion indices;therefore a minimum expense of control could be adopted to measure the consequence of the disturbance on the transmission network operation.Through sampling method,the probability and consequence of each situation occurrence could be acquired;and with the assistance of calculating value at risk and conditional value-at-risk,the security risk of transmission network could be evaluated properly.%输电网的安全运行是输电网企业的主要需求,输电网运行的安全性事故将造成输电网企业经济和社会效益的严重损失。输电网企业期望输电网运行中能够经受可能的

  9. Global climate change and its potential impact on disease transmission by salinity-tolerant mosquito vectors in coastal zones.

    Science.gov (United States)

    Ramasamy, Ranjan; Surendran, Sinnathamby Noble

    2012-01-01

    Global climate change can potentially increase the transmission of mosquito vector-borne diseases such as malaria, lymphatic filariasis, and dengue in many parts of the world. These predictions are based on the effects of changing temperature, rainfall, and humidity on mosquito breeding and survival, the more rapid development of ingested pathogens in mosquitoes and the more frequent blood feeds at moderately higher ambient temperatures. An expansion of saline and brackish water bodies (water with 30 ppt salt are termed fresh, brackish, and saline respectively) will also take place as a result of global warming causing a rise in sea levels in coastal zones. Its possible impact on the transmission of mosquito-borne diseases has, however, not been adequately appreciated. The relevant impacts of global climate change on the transmission of mosquito-borne diseases in coastal zones are discussed with reference to the Ross-McDonald equation and modeling studies. Evidence is presented to show that an expansion of brackish water bodies in coastal zones can increase the densities of salinity-tolerant mosquitoes like Anopheles sundaicus and Culex sitiens, and lead to the adaptation of fresh water mosquito vectors like Anopheles culicifacies, Anopheles stephensi, Aedes aegypti, and Aedes albopictus to salinity. Rising sea levels may therefore act synergistically with global climate change to increase the transmission of mosquito-borne diseases in coastal zones. Greater attention therefore needs to be devoted to monitoring disease incidence and preimaginal development of vector mosquitoes in artificial and natural coastal brackish/saline habitats. It is important that national and international health agencies are aware of the increased risk of mosquito-borne diseases in coastal zones and develop preventive and mitigating strategies. Application of appropriate counter measures can greatly reduce the potential for increased coastal transmission of mosquito-borne diseases

  10. Analysis of changes in recent tuberculosis transmission patterns after a sharp increase in immigration.

    Science.gov (United States)

    Iñigo, Jesús; García de Viedma, Darío; Arce, Araceli; Palenque, Elia; Alonso Rodríguez, Noelia; Rodríguez, Elena; Ruiz Serrano, María Jesús; Andrés, Sandra; Bouza, Emilio; Chaves, Fernando

    2007-01-01

    We conducted a population-based molecular epidemiological study of tuberculosis (TB) in Madrid, Spain (2002 to 2004), to define transmission patterns and factors associated with clustering. We particularly focused on examining how the increase in TB cases among immigrants in recent years (2.8% in 1997 to 1999 to 36.2% during the current study) was modifying transmission patterns. Mycobacterium tuberculosis isolates obtained from patients living in nine districts of Madrid (1,459,232 inhabitants) were genotyped. The TB case rate among foreign-born people was three to four times that of Spanish-born people, and the median time from arrival to the onset of treatment was 22.4 months. During the study period, 227 (36.3%) patients were grouped in 64 clusters, and 115 (50.7%) of them were in 21 clusters with mixed Spanish-born and foreign-born patients. Three of the 21 mixed clusters accounted for 21.1% of clustered patients. Twenty-two of 38 (57.9%) immigrants in mixed clusters were infected with TB strains that had already been identified in the native population in 1997 to 1999, including the three most prevalent strains. Factors identified as independent predictors of clustering were homelessness (odds ratio [OR], 2.3; 95% confidence interval [95% CI], 1.2 to 4.5; P = 0.011) and to be born in Spain (OR, 1.8; 95% CI, 1.2 to 2.6; P = 0.002). The results indicated that (i) TB transmission was higher in Spanish-born people, associated mainly with homelessness, (ii) that foreign-born people were much less likely to be clustered, suggesting a higher percentage of infection before arriving in Spain, and (iii) that an extensive transmission between Spanish- and foreign-born populations, caused mainly by autochthonous strains, was taking place in Madrid.

  11. Effects of construction changes in the teeth of a gear transmission on acoustic properties.

    Science.gov (United States)

    Wieczorek, Andrzej

    2012-01-01

    This paper presents results of experimental research on the acoustic properties of gear wheels with high-profile teeth with differentiated tooth height. Those results showed that gear transmissions with high-profile teeth have the best acoustic properties, with the value of the transverse contact ratio εα ≈ 2.0. They also showed that a reduction in tooth height, and thereby in contact ratio, increased the sound pressure level.

  12. Metabolic and Kidney Diseases in the Setting of Climate Change, Water Shortage, and Survival Factors.

    Science.gov (United States)

    Johnson, Richard J; Stenvinkel, Peter; Jensen, Thomas; Lanaspa, Miguel A; Roncal, Carlos; Song, Zhilin; Bankir, Lise; Sánchez-Lozada, Laura G

    2016-08-01

    Climate change (global warming) is leading to an increase in heat extremes and coupled with increasing water shortage, provides a perfect storm for a new era of environmental crises and potentially, new diseases. We use a comparative physiologic approach to show that one of the primary mechanisms by which animals protect themselves against water shortage is to increase fat mass as a means for providing metabolic water. Strong evidence suggests that certain hormones (vasopressin), foods (fructose), and metabolic products (uric acid) function as survival signals to help reduce water loss and store fat (which also provides a source of metabolic water). These mechanisms are intricately linked with each other and stimulated by dehydration and hyperosmolarity. Although these mechanisms were protective in the setting of low sugar and low salt intake in our past, today, the combination of diets high in fructose and salty foods, increasing temperatures, and decreasing available water places these survival signals in overdrive and may be accelerating the obesity and diabetes epidemics. The recent discovery of multiple epidemics of CKD occurring in agricultural workers in hot and humid environments may represent harbingers of the detrimental consequences of the combination of climate change and overactivation of survival pathways.

  13. School-based surveys of malaria in Oromia Regional State, Ethiopia: a rapid survey method for malaria in low transmission settings

    Directory of Open Access Journals (Sweden)

    Pullan Rachel L

    2011-02-01

    were identified within Oromia. Conclusion These findings demonstrate the marked spatial heterogeneity of malaria in Oromia and, in general, Ethiopia, and provide a strong epidemiological basis for planning as well as monitoring and evaluating malaria control in a setting with seasonal and unstable malaria transmission.

  14. Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change

    Directory of Open Access Journals (Sweden)

    Yang Guo-Jing

    2012-12-01

    Full Text Available Abstract Background A sound understanding of malaria transmission patterns in the People’s Republic of China (P.R. China is crucial for designing effective surveillance-response strategies that can guide the national malaria elimination programme (NMEP. Using an established biology-driven model, it is expected that one may design and refine appropriate surveillance-response strategies for different transmission zones, which, in turn, assist the NMEP in the ongoing implementation period (2010–2020 and, potentially, in the post-elimination stage (2020–2050. Methods Environmental data obtained from 676 locations across P.R. China, such as monthly temperature and yearly relative humidity (YRH, for the period 1961–2000 were prepared. Smoothed surface maps of the number of months suitable for parasite survival derived from monthly mean temperature and YRH were generated. For each decade, the final malaria prediction map was overlaid by two masked maps, one showing the number of months suitable for parasite survival and the other the length of YRH map in excess of 60%. Results Considering multiple environmental factors simultaneously, the environmental variables suitable for malaria transmission were found to have shifted northwards, which was especially pronounced in northern P.R. China. The unstable suitable regions (transmission periods between five and six months showed increased transmission intensity due to prolonged suitable periods, especially in the central part of the country. Conclusion Adequate and effective surveillance-response strategies for NMEP should be designed to achieve the goal of malaria elimination in P.R. China by 2020, especially in the zones predicted to be the most vulnerable for climate change.

  15. Alteration of PHYA expression change circadian rhythms and timing of bud set in Populus.

    Science.gov (United States)

    Kozarewa, Iwanka; Ibáñez, Cristian; Johansson, Mikael; Ogren, Erling; Mozley, David; Nylander, Eva; Chono, Makiko; Moritz, Thomas; Eriksson, Maria E

    2010-05-01

    In many temperate woody species, dormancy is induced by short photoperiods. Earlier studies have shown that the photoreceptor phytochrome A (phyA) promotes growth. Specifically, Populus plants that over-express the oat PHYA gene (oatPHYAox) show daylength-independent growth and do not become dormant. However, we show that oatPHYAox plants could be induced to set bud and become cold hardy by exposure to a shorter, non-24 h diurnal cycle that significantly alters the relative position between endogenous rhythms and perceived light/dark cycles. Furthermore, we describe studies in which the expression of endogenous Populus tremula x P. tremuloides PHYTOCHROME A (PttPHYA) was reduced in Populus trees by antisense inhibition. The antisense plants showed altered photoperiodic requirements, resulting in earlier growth cessation and bud formation in response to daylength shortening, an effect that was explained by an altered innate period that leads to phase changes of clock-associated genes such as PttCO2. Moreover, gene expression studies following far-red light pulses show a phyA-mediated repression of PttLHY1 and an induction of PttFKF1 and PttFT. We conclude that the level of PttPHYA expression strongly influences seasonally regulated growth in Populus and is central to co-ordination between internal clock-regulated rhythms and external light/dark cycles through its dual effect on the pace of clock rhythms and in light signaling.

  16. In situ transmission electron microscopy investigation of the structural changes in carbon nanotubes during electron emission at high currents

    Energy Technology Data Exchange (ETDEWEB)

    Doytcheva, Maya [Philips Research, Professor Holstlaan 4, 5656 AA Eindhovene (Netherlands); Kaiser, Monja [Philips Research, Professor Holstlaan 4, 5656 AA Eindhoven (Netherlands); Jonge, Niels de [Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, TN 37831-6030 (United States)

    2006-07-14

    The structural changes in carbon nanotubes under electron emission conditions were investigated in situ in a transmission electron microscope (TEM). The measurements were performed on individually mounted free-standing multi-walled carbon nanotubes (CNTs). It was found that the structure of the carbon nanotubes did not change gradually, as is the case with field emission electron sources made of sharp metal tips. Instead, changes occurred only above a current level of a few microamperes, which was different for each nanotube. Above the threshold current, carbon nanotubes underwent either structural damage, such as shortening and splitting of the apex of the nanotube, or closing of their open cap. The results are discussed on the basis of several models for degradation mechanisms.

  17. In situ Transmission Electron Microscopy Investigation of the Structural Changes in Carbon Nanotubes During Electron Emission at High Currents

    Energy Technology Data Exchange (ETDEWEB)

    Doytcheva, Maya [Philips Research, The Netherlands; Kaiser, Monja [Philips Research, The Netherlands; De Jonge, Niels [ORNL

    2006-01-01

    The structural changes in carbon nanotubes under electron emission conditions were investigated in situ in a transmission electron microscope (TEM). The measurements were performed on individually mounted free-standing multi-walled carbon nanotubes (CNTs). It was found that the structure of the carbon nanotubes did not change gradually, as is the case with field emission electron sources made of sharp metal tips. Instead, changes occurred only above a current level of a few microamperes, which was different for each nanotube. Above the threshold current, carbon nanotubes underwent either structural damage, such as shortening and splitting of the apex of the nanotube, or closing of their open cap. The results are discussed on the basis of several models for degradation mechanisms.

  18. Optical transmission and laser ablation of pathologically changed eye lens capsule

    Energy Technology Data Exchange (ETDEWEB)

    Gamidov, A A; Bolshunov, A V [Research Institute of Eye Diseases, Russian Academy of Medical Sciences, Moscow (Russian Federation); Yuzhakov, A V; Shcherbakov, E M; Baum, O I; Sobol, E N [Institute on Laser and Information Technologies, Russian Academy of Sciences, Shatura, Moscow Region (Russian Federation)

    2015-02-28

    Optical transmission and ablation mechanisms in the secondary cataract films under the impact of 1.06-mm laser radiation are studied. The comparison of incident and transmitted (paraxial) radiation power at different values of the power density is carried out for two types of the eye lens capsule tissue (hard and soft) possessing different optical and mechanical properties. It is found that the effective attenuation coefficient for soft films is almost five times as large as that for the hard ones. The obtained measurement data on the transparency variation in the process of laser action allow the temperature evaluation and the determination of dominant mechanism of laser ablation, as well as the development of recommendations, providing the prevention or reduction of possible side effects. The obtained results can be used to optimise the regimes of laser impact in the process of the opacified lens capsule removal.

  19. Effects of elevation change on mental stress in high-voltage transmission tower construction workers.

    Science.gov (United States)

    Hsu, Feng-Wen; Lin, Chiuhsiang Joe; Lee, Yung-Hui; Chen, Hung-Jen

    2016-09-01

    High-voltage transmission tower construction is a high-risk operation due to the construction site locations, extreme climatic factors, elevated working surfaces, and narrow working space. To comprehensively enhance our understanding of the psychophysiological phenomena of workers in extremely high tower constructions, we carried out a series of field experiments to test and compare three working surface heights in terms of frequency-domain heart rate variability (HRV) measurements. Twelve experienced male workers participated in this experiment. The dependent variables, namely, heart rate (HR), normalized low-frequency power (nLF), normalized high-frequency power (nHF), and LF-to-HF power ratio (LF/HF), were measured with the Polar RS800CX heart rate monitor. The experimental results indicated that the task workload was similar between working surface heights. Tower construction workers perceived an increased level of mental stress as working surface height increased.

  20. Age-related changes in visual exploratory behavior in a natural scene setting

    Directory of Open Access Journals (Sweden)

    Johanna eHamel

    2013-06-01

    Full Text Available Diverse cognitive functions decline with increasing age, including the ability to process central and peripheral visual information in a laboratory testing situation (useful visual field of view. To investigate whether and how this influences activities of daily life, we studied age-related changes in visual exploratory behavior in a natural scene setting: a driving simulator paradigm of variable complexity was tested in subjects of varying ages with simultaneous eye- and head-movement recordings via a head-mounted camera. Detection and reaction times were also measured by visual fixation and manual reaction. We considered video computer game experience as a possible influence on performance. Data of 73 participants of varying ages were analyzed, driving two different courses. We analyzed the influence of route difficulty level, age and eccentricity of test stimuli on oculomotor and driving behavior parameters. No significant age effects were found regarding saccadic parameters. In the older subjects head-movements increasingly contributed to gaze amplitude. More demanding courses and more peripheral stimuli locations, induced longer reaction times in all age groups. Deterioration of the functionally useful visual field of view with increasing age was not suggested in our study group. However, video game-experienced subjects revealed larger saccade amplitudes and a broader distribution of fixations on the screen. They reacted faster to peripheral objects suggesting the notion of a general detection task rather than perceiving driving as a central task. As the video game experienced population consisted of younger subjects, our study indicates that effects due to video game experience can easily be misinterpreted as age effects if not accounted for. We therefore view it as essential to consider video game experience in all testing methods using virtual media.

  1. Density changes in shear bands of a metallic glass determined by correlative analytical transmission electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Rösner, Harald, E-mail: rosner@uni-muenster.de [Institut für Materialphysik, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Strasse 10, D-48149 Münster (Germany); Peterlechner, Martin [Institut für Materialphysik, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Strasse 10, D-48149 Münster (Germany); Kübel, Christian [Karlsruhe Institute of Technology (KIT), Institute of Nanotechnology (INT), Hermann-von-Helmholtz-Platz 1, D-76344 Eggenstein-Leopoldshafen (Germany); Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), D-76344 Eggenstein-Leopoldshafen (Germany); Schmidt, Vitalij [Institut für Materialphysik, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Strasse 10, D-48149 Münster (Germany); Wilde, Gerhard [Institut für Materialphysik, Westfälische Wilhelms-Universität Münster, Wilhelm-Klemm-Strasse 10, D-48149 Münster (Germany); Institute of Nanochemistry and Nanobiology, School of Environmental and Chemical Engineering, Shanghai University, Shanghai 200444 (China)

    2014-07-01

    Density changes between sheared zones and their surrounding amorphous matrix as a result of plastic deformation in a cold-rolled metallic glass (melt-spun Al{sub 88}Y{sub 7}Fe{sub 5}) were determined using high-angle annular dark-field (HAADF) detector intensities supplemented by electron-energy loss spectroscopy (EELS), energy-dispersive X-ray (EDX) and nano-beam diffraction analyses. Sheared zones or shear bands were observed as regions of bright or dark contrast arising from a higher or lower density relative to the matrix. Moreover, abrupt contrast changes from bright to dark and vice versa were found within individual shear bands. We associate the decrease in density mainly with an enhanced free volume in the shear bands and the increase in density with concomitant changes of the mass. This interpretation is further supported by changes in the zero loss and Plasmon signal originating from such sites. The limits of this new approach are discussed. - Highlights: • We describe a novel approach for measuring densities in shear bands of metallic glasses. • The linear relation of the dark-field intensity I/I{sub 0} and the mass thickness ρt was used. • Individual shear bands showed abrupt contrast changes from bright to dark and vice versa. • Density changes ranging from about −10% to +6% were found for such shear bands. • Mixtures of amorphous/medium range ordered domains were found within the shear bands.

  2. Changes in Adult Behavior to Decrease Disruption from Students in Nonclassroom Settings

    Science.gov (United States)

    Bohanon, Hank

    2015-01-01

    Decreasing classroom disruptions that result from hallway-related behavior in high school settings can be very challenging for high school staff. This article presents a case example of preventing problem behavior related to hallway settings in a high school with over 1,200 students. The interventions are described, and the results of the plan are…

  3. Evaluation of circulating cathodic antigen (CCA) urine-cassette assay as a survey tool for Schistosoma mansoni in different transmission settings within Bugiri District, Uganda.

    Science.gov (United States)

    Adriko, M; Standley, C J; Tinkitina, B; Tukahebwa, E M; Fenwick, A; Fleming, F M; Sousa-Figueiredo, J C; Stothard, J R; Kabatereine, N B

    2014-08-01

    Diagnosis of schistosomiasis at the point-of-care (POC) is a growing topic in neglected tropical disease research. There is a need for diagnostic tests which are affordable, sensitive, specific, user-friendly, rapid, equipment-free and delivered to those who need it, and POC is an important tool for disease mapping and guiding mass deworming. The aim of present study was to evaluate the relative diagnostic performance of two urine-circulating cathodic antigen (CCA) cassette assays, one commercially available and the other in experimental production, against results obtained using the standard Kato-Katz faecal smear method (six thick smears from three consecutive days), as a 'gold-standard', for Schistosoma mansoni infection in different transmission settings in Uganda. Our study was conducted among 500 school children randomly selected across 5 schools within Bugiri district, adjacent to Lake Victoria in Uganda. Considering results from the 469 pupils who provided three stool samples for the six Kato-Katz smears, 293 (76%) children had no infection, 109 (23%) were in the light intensity category, while 42 (9%) and 25 (5%) were in the moderate and heavy intensity categories respectively. Following performance analysis of CCA tests in terms of sensitivity, specificity, negative and positive predictive values, overall performance of the commercially available CCA test was more informative than single Kato-Katz faecal smear microscopy, the current operational field standard for disease mapping. The current CCA assay is therefore a satisfactory method for surveillance of S. mansoni in an area where disease endemicity is declining due to control interventions. With the recent resolution on schistosomiasis elimination by the 65th World Health Assembly, the urine POC CCA test is an attractive tool to augment and perhaps replace the Kato-Katz sampling within ongoing control programmes.

  4. Fundamental analysis and development of the current and voltage control method by changing the driving frequency for the transcutaneous energy transmission system.

    Science.gov (United States)

    Miura, Hidekazu; Yamada, Akihiro; Shiraishi, Yasuyuki; Yambe, Tomoyuki

    2015-08-01

    We have been developing transcutaneous energy transmission system (TETS) for a ventricular assist device, shape memory alloy (SMA) fibered artificial organs and so on, the system has high efficiency and a compact size. In this paper, we summarize the development, design method and characteristics of the TETS. New control methods for stabilizing output voltage or current of the TETS are proposed. These methods are primary side, are outside of the body, not depending on a communication system from the inside the body. Basically, the TETS operates at the fixed frequency with a suitable compensation capacitor so that the internal impedance is minimalized and a flat load characteristic is obtained. However, when the coil shifted from the optimal position, the coupling factor changes and the output is fluctuated. TETS has a resonant property; its output can be controlled by changing the driving frequency. The continuous current to continuous voltage driving method was implemented by changing driving frequency and setting of limitation of low side frequency. This method is useful for battery charging system for electrically driven artificial hearts and also useful for SMA fibered artificial organs which need intermittent high peak power comsumption. In this system, the internal storage capacitor is charged slowly while the fibers are turned off and discharge the energy when the fibers are turned on. We examined the effect of the system. It was found that the size and maximum output of the TETS would able to be reduced.

  5. Indicators for Tracking European Vulnerabilities to the Risks of Infectious Disease Transmission due to Climate Change

    Directory of Open Access Journals (Sweden)

    Jonathan E. Suk

    2014-02-01

    Full Text Available A wide range of infectious diseases may change their geographic range, seasonality and incidence due to climate change, but there is limited research exploring health vulnerabilities to climate change. In order to address this gap, pan-European vulnerability indices were developed for 2035 and 2055, based upon the definition vulnerability = impact/adaptive capacity. Future impacts were projected based upon changes in temperature and precipitation patterns, whilst adaptive capacity was developed from the results of a previous pan-European study. The results were plotted via ArcGISTM to EU regional (NUTS2 levels for 2035 and 2055 and ranked according to quintiles. The models demonstrate regional variations with respect to projected climate-related infectious disease challenges that they will face, and with respect to projected vulnerabilities after accounting for regional adaptive capacities. Regions with higher adaptive capacities, such as in Scandinavia and central Europe, will likely be better able to offset any climate change impacts and are thus generally less vulnerable than areas with lower adaptive capacities. The indices developed here provide public health planners with information to guide prioritisation of activities aimed at strengthening regional preparedness for the health impacts of climate change. There are, however, many limitations and uncertainties when modeling health vulnerabilities. To further advance the field, the importance of variables such as coping capacity and governance should be better accounted for, and there is the need to systematically collect and analyse the interlinkages between the numerous and ever-expanding environmental, socioeconomic, demographic and epidemiologic datasets so as to promote the public health capacity to detect, forecast, and prepare for the health threats due to climate change.

  6. Expansion of HAART coverage is associated with sustained decreases in HIV/AIDS morbidity, mortality and HIV transmission: the "HIV Treatment as Prevention" experience in a Canadian setting.

    Directory of Open Access Journals (Sweden)

    Julio S G Montaner

    Full Text Available BACKGROUND: There has been renewed call for the global expansion of highly active antiretroviral therapy (HAART under the framework of HIV treatment as prevention (TasP. However, population-level sustainability of this strategy has not been characterized. METHODS: We used population-level longitudinal data from province-wide registries including plasma viral load, CD4 count, drug resistance, HAART use, HIV diagnoses, AIDS incidence, and HIV-related mortality. We fitted two Poisson regression models over the study period, to relate estimated HIV incidence and the number of individuals on HAART and the percentage of virologically suppressed individuals. RESULTS: HAART coverage, median pre-HAART CD4 count, and HAART adherence increased over time and were associated with increasing virological suppression and decreasing drug resistance. AIDS incidence decreased from 6.9 to 1.4 per 100,000 population (80% decrease, p = 0.0330 and HIV-related mortality decreased from 6.5 to 1.3 per 100,000 population (80% decrease, p = 0.0115. New HIV diagnoses declined from 702 to 238 cases (66% decrease; p = 0.0004 with a consequent estimated decline in HIV incident cases from 632 to 368 cases per year (42% decrease; p = 0.0003. Finally, our models suggested that for each increase of 100 individuals on HAART, the estimated HIV incidence decreased 1.2% and for every 1% increase in the number of individuals suppressed on HAART, the estimated HIV incidence also decreased by 1%. CONCLUSIONS: Our results show that HAART expansion between 1996 and 2012 in BC was associated with a sustained and profound population-level decrease in morbidity, mortality and HIV transmission. Our findings support the long-term effectiveness and sustainability of HIV treatment as prevention within an adequately resourced environment with no financial barriers to diagnosis, medical care or antiretroviral drugs. The 2013 Consolidated World Health Organization Antiretroviral

  7. Is routine replacement of i.v. administration sets required after each change of intermittently administrated antibiotic infusions?

    Directory of Open Access Journals (Sweden)

    von Au, Felix

    2013-04-01

    Full Text Available [english] Aim: Manufacturers’ instructions recommend changing the infusion line together with the infusion bottle after each administration. We investigated if the complete infusion line may be microbiologically contaminated after short-time antibiotic and rinse-solution application.Method: Immediately after the change of an infusion administration set after 72 hours the remaining antibiotic solution was inactivated with yolk and cultured on blood agar for 48 hours at 36°C to detect possible contaminants.Results: Among 87 investigated samples no microbial growth was detected. One sample which hadn’t any contact to antibiotics yielded forming unit (cfu of coagulase-negative staphylococci.These results suggest that in case of consecutive antibiotic-short- and rinse-infusions the infusion line may be in place up to 72 hours without contamination. This, however, may be only the case for infusion sets, which are in contact with antibiotics. If no antibiotic is administered, the infusion bottle and the infusion line must be renewed together for every change. To clarify this question into more detail, a larger consecutive study is required. Conclusion: I.v. administration sets without any contact to antibiotics must be changed together with their infusion bottle after administration. In case of consecutive antibiotic-short- and rinse-infusions our pilot study suggests using the i.v. administration sets for up to 72 hours without renewing it at every infusion-set exchange.

  8. Design of synchromesh mechanism to optimization manual transmission's electric vehicle

    Science.gov (United States)

    Zainuri, Fuad; Sumarsono, Danardono A.; Adhitya, Muhammad; Siregar, Rolan

    2017-03-01

    Significant research has been attempted on a vehicle that lead to the development of transmission that can reduce energy consumption and improve vehicle efficiency. Consumers also expect safety, convenience, and competitive prices. Automatic transmission (AT), continuously variable transmission (CVT), and dual clutch transmission (DCT) is the latest transmission developed for road vehicle. From literature reviews that have been done that this transmission is less effective on electric cars which use batteries as a power source compared to type manual transmission, this is due to the large power losses when making gear changes. Zeroshift system is the transmission can do shift gears with no time (zero time). It was developed for the automatic manual transmission, and this transmission has been used on racing vehicles to eliminate deceleration when gear shift. Zeroshift transmission still use the clutch to change gear in which electromechanical be used to replace the clutch pedal. Therefore, the transmission is too complex for the transmission of electric vehicles, but its mechanism is considered very suitable to increase the transmission efficiency. From this idea, a new innovation design transmission will be created to electric car. The combination synchromesh with zeroshift mechanism for the manual transmission is a transmission that is ideal for improving the transmission efficiency. Installation synchromesh on zeroshift mechanism is expected to replace the function of the clutch MT, and assisted with the motor torque setting when to change gear. Additionally to consider is the weight of the transmission, ease of manufacturing, ease of installation with an electric motor, as well as ease of use by drivers is a matter that must be done to obtain a new transmission system that is suitable for electric cars.

  9. Arbitrary vehicle steering characteristics with changing ratio rack and pinion transmission

    Directory of Open Access Journals (Sweden)

    András G Bendefy

    2015-12-01

    Full Text Available In order to achieve arbitrary steering characteristics at vehicles, a steering mechanism was developed, in which changing ratio rack and pinion connections have been applied. In contrary to a regular steering mechanism where only a single rack is used, two racks were applied in order to make arbitrary characteristics possible. The turning wheel’s required motion functions had to be defined first, thereafter could we determine the changing ratio rack and pinion geometry which produces this motion. First, a simplified two-dimensional mockup was created in order to study the difficulties and possibilities of a real construction. Later, a fully functional assembly was designed and manufactured to make further experiments possible.

  10. Pathways of information transmission among wild songbirds follow experimentally imposed changes in social foraging structure.

    Science.gov (United States)

    Firth, Josh A; Sheldon, Ben C; Farine, Damien R

    2016-06-01

    Animals regularly use information from others to shape their decisions. Yet, determining how changes in social structure affect information flow and social learning strategies has remained challenging. We manipulated the social structure of a large community of wild songbirds by controlling which individuals could feed together at automated feeding stations (selective feeders). We then provided novel ephemeral food patches freely accessible to all birds and recorded the spread of this new information. We demonstrate that the discovery of new food patches followed the experimentally imposed social structure and that birds disproportionately learnt from those whom they could forage with at the selective feeders. The selective feeders reduced the number of conspecific information sources available and birds subsequently increased their use of information provided by heterospecifics. Our study demonstrates that changes to social systems carry over into pathways of information transfer and that individuals learn from tutors that provide relevant information in other contexts.

  11. Tracing defaulters in HIV prevention of mother-to-child transmission programmes through community health workers: results from a rural setting in Zimbabwe.

    OpenAIRE

    Florian Vogt; Cecilia Ferreyra; Andrea Bernasconi; Lewis Ncube; Fabian Taziwa; Winnie Marange; David Wachi; Heiko Becher

    2015-01-01

    Introduction: High retention in care is paramount to reduce vertical human immunodeficiency virus (HIV) infections in prevention of mother-to-child transmission (PMTCT) programmes but remains low in many sub-Saharan African countries. We aimed to assess the effects of community health worker–based defaulter tracing (CHW-DT) on retention in care and mother-to-child HIV transmission, an innovative approach that has not been evaluated to date. Methods: We analyzed patient records of 1878 HIV-pos...

  12. Changes in the drug release pattern of fresh and set simvastatin-loaded brushite cement.

    Science.gov (United States)

    Mestres, Gemma; Kugiejko, Karol; Pastorino, David; Unosson, Johanna; Öhman, Caroline; Karlsson Ott, Marjam; Ginebra, Maria-Pau; Persson, Cecilia

    2016-01-01

    Calcium phosphate cements are synthetic bone graft substitutes able to set at physiological conditions. They can be applied by minimally invasive surgery and can also be used as drug delivery systems. Consequently, the drug release pattern from the cement paste (fresh cement) is of high clinical interest. However, previous studies have commonly evaluated the drug release using pre-set cements only. Therefore, the aim of this work was to determine if the time elapsed from cement preparation until immersion in the solution (3 min for fresh cements, and 1h and 15 h for pre-set cements) had an influence on its physical properties, and correlating these to the drug release profile. Simvastatin was selected as a model drug, while brushite cement was used as drug carrier. This study quantified how the setting of a material reduces the accessibility of the release media to the material, thus preventing drug release. A shift in the drug release pattern was observed, from a burst-release for fresh cements to a sustained release for pre-set cements.

  13. Changing malaria transmission and implications in China towards National Malaria Elimination Programme between 2010 and 2012.

    Directory of Open Access Journals (Sweden)

    Jian-hai Yin

    Full Text Available BACKGROUND: Towards the implementation of national malaria elimination programme in China since 2010, the epidemiology of malaria has changed dramatically, and the lowest malaria burden was achieved yearly. It is time to analyze the changes of malaria situation based on surveillance data from 2010 to 2012 to reconsider the strategies for malaria elimination. METHODS AND PRINCIPAL FINDINGS: Malaria epidemiological data was extracted from the provincial annual reports in China between 2010 and 2012. The trends of the general, autochthonous and imported malaria were analyzed, and epidemic areas were reclassified according to Action Plan of China Malaria Elimination (2010-2020. As a result, there reported 2743 malaria cases with a continued decline in 2012, and around 7% autochthonous malaria cases accounted. Three hundred and fifty-three individual counties from 19 provincial regions had autochthonous malaria between 2010 and 2012, and only one county was reclassified into Type I (local infections detected in 3 consecutive years and the annual incidences ≥ 1/10,000 again. However, the imported malaria cases reported of each year were widespread, and 598 counties in 29 provinces were suffered in 2012. CONCLUSIONS/SIGNIFICANCE: Malaria was reduced significantly from 2010 to 2012 in China, and malaria importation became an increasing challenge. It is necessary to adjust or update the interventions for subsequent malaria elimination planning and resource allocation.

  14. Predicting Plausible Impacts of Sets of Climate and Land Use Change Scenario on Water Resources

    Science.gov (United States)

    As the new decade ushers in, there will be new challenges. The world’s population is increasing and the land use patterns are changing. Inevitably with these global changes, there will be various environmental consequences. For example, our water resources, both in terms of qu...

  15. Climate Change Education in Formal Settings, K-14: A Workshop Summary

    Science.gov (United States)

    Beatty, Alexandra

    2012-01-01

    Climate change is occurring, is very likely caused by human activities, and poses significant risks for a broad range of human and natural systems. Each additional ton of greenhouse gases emitted commits us to further change and greater risks. In the judgment of the Committee on America's Climate Choices, the environmental, economic, and…

  16. A coherent set of future land use change scenarios for Europe

    DEFF Research Database (Denmark)

    Rounsevell, M. D. A.; Reginster, I.; Araújo, Miguel B.

    2006-01-01

    This paper presents a range of future, spatially explicit, land use change scenarios for the EU15, Norway and Switzerland based on an interpretation of the global storylines of the Intergovernmental Panel on Climate Change (IPCC) that are presented in the special report on emissions scenarios (SRES......). The methodology is based on a qualitative interpretation of the SRES storylines for the European region, an estimation of the aggregate totals of land use change using various land use change models and the allocation of these aggregate quantities in space using spatially explicit rules. The spatial patterns...... are further downscaled from a resolution of 10 min to 250 m using statistical downscaling procedures. The scenarios include the major land use/land cover classes urban, cropland, grassland and forest land as well as introducing new land use classes such as bioenergy crops. The scenario changes are most...

  17. Potential Confounding in Evaluating Infection-Control Interventions in Hospital Settings : Changing Antibiotic Prescription

    NARCIS (Netherlands)

    Nijssen, S.; Bootsma, M.C.; Bonten, M.

    2006-01-01

    The colonization dynamics of antibiotic-resistant pathogens in hospital settings are complex, with multiple and continuously interacting variables (e.g., introduction of resistance, infection-control practices, antibiotic use). Quantification of these variables is indispensable in the evaluation of

  18. Between credit claiming and blame avoidance: the changing politics of priority-setting for Korea's National Health Insurance System.

    Science.gov (United States)

    Kang, Minah; Reich, Michael R

    2014-03-01

    Priority-setting involves diverse parties with intense and often conflicting interests and values. Still, the political aspects of priority-setting are largely unexplored in the literature on health policy. In this paper, we examine how policy makers in Korea changed their strategies as the policy context for priority setting changed from only expanding benefits to a double burden of benefit expansion plus cost containment. This analysis shows that priority-setting is a profoundly political process. The policy context shapes how policy makers choose their political strategies. In particular, we find that policy makers sway between "credit claiming" and "blame avoidance" strategies. Korean policy makers resorted to three types of political strategies when confronted with a double burden of benefit expansion and cost containment: delegating responsibility to other institutions (agency strategies), replacing judgment-based decisions with automatic rules (policy strategies), and focusing on the presentation of how decisions are made (presentational strategies). The paper suggests implications for future studies on priority-setting in the Korean health care system and in other countries that face similar challenges, and concludes that Korean policy makers need to put more effort into developing transparent and systematic priority-setting processes, especially in times of double burden of benefit expansion and cost containment.

  19. UV Laser Induced Transmission Change of Pure and Doped Silica Glass

    Institute of Scientific and Technical Information of China (English)

    XIE Junlin; DENG Tao; LUO Jie; BAN Qingrong

    2008-01-01

    Pure and F,GeO2-doped silica glass cut from fiber preforms prepared by plasma assisted chemical vapor deposition(PCVD) were investigated by ultraviolet absorption spectroscopy.The ultraviolet absorption characteristics of these glasses were also studied after UV laser irradiation and heating treatment.It was found that absorption band near 240 nm assigned to GODC was found both in GeO2-doped and F-GeO2 co-doped silica glass,but absorption intensity of the latter was lower than that of the former.It's because F can react with GODC and GeE' simultaneously and reduce their concentration.After irradiation,UV absorption change of F-GeO2 co-doped silica glass was weaker than that of GeO2-doped silica glass,it thus can be concluded that introduction of F could depress the UV absorption of GeO2-doped silica core effectively.

  20. Potential Confounding in Evaluating Infection-Control Interventions in Hospital Settings : Changing Antibiotic Prescription

    OpenAIRE

    Nijssen, S; Bootsma, M.C.; Bonten, M

    2006-01-01

    The colonization dynamics of antibiotic-resistant pathogens in hospital settings are complex, with multiple and continuously interacting variables (e.g., introduction of resistance, infection-control practices, antibiotic use). Quantification of these variables is indispensable in the evaluation of intervention studies, because these variables represent potential confounders. In this article, the complexity of colonization dynamics is described. Through a systematic review, we identified stud...

  1. Enhancing and expanding intersectional research for climate change adaptation in agrarian settings.

    Science.gov (United States)

    Thompson-Hall, Mary; Carr, Edward R; Pascual, Unai

    2016-12-01

    Most current approaches focused on vulnerability, resilience, and adaptation to climate change frame gender and its influence in a manner out-of-step with contemporary academic and international development research. The tendency to rely on analyses of the sex-disaggregated gender categories of 'men' and 'women' as sole or principal divisions explaining the abilities of different people within a group to adapt to climate change, illustrates this problem. This framing of gender persists in spite of established bodies of knowledge that show how roles and responsibilities that influence a person´s ability to deal with climate-induced and other stressors emerge at the intersection of diverse identity categories, including but not limited to gender, age, seniority, ethnicity, marital status, and livelihoods. Here, we provide a review of relevant literature on this topic and argue that approaching vulnerability to climate change through intersectional understandings of identity can help improve adaptation programming, project design, implementation, and outcomes.

  2. Climaite - a three factor climate change ecosystem manipulation study: set up and approaches for data analysis

    DEFF Research Database (Denmark)

    N. Mikkelsen, Teis; Beier, Claus; Schmidt, Inger Kappel;

    In a new Danish climate change related field scale experiment, CLIMAITE, we are investigating the impacts of individual and multiple simultaneous global changes on ecosystem processes and functioning in a Danish semi natural grassland vegetation dominated by Deschampsia flexuosa and Calluna...... vulgaris. The Climaite experiment involves three global change factors: elevated CO2 (510 ppm), elevated temperature (+ 1-2 C) and altered precipitation (1-1.5 months extended drought in May-July) all compared to ambient conditions in a complete factorial design. The experiment includes six replicates......, the physiological status of plants, soil water chemistry and emission of green house gasses. The CO2 is enhanced all year around during daylight hours in 6 plots by the use of a FACE system (F. Miglietta design). Temperature elevation is achieved by night time warming where IR reflective curtains automatically...

  3. Climaite - a three factor climate change ecosystem manipulation study: set up and approaches for data analysis

    DEFF Research Database (Denmark)

    N. Mikkelsen, Teis; Beier, Claus; Schmidt, Inger Kappel;

    (based on vegetation analysis) containing each of the 8 treatments. Prior to initiation of the treatments 3rd October 2005, pre treatment measurements and studies were conducted for establishing the initial status of key variables e.g. soil and air temperature, soil moisture, species composition......In a new Danish climate change related field scale experiment, CLIMAITE, we are investigating the impacts of individual and multiple simultaneous global changes on ecosystem processes and functioning in a Danish semi natural grassland vegetation dominated by Deschampsia flexuosa and Calluna...

  4. Trends and issues in land and water resources management: Setting the agenda for change

    Science.gov (United States)

    Cortner, Hanna J.; Moote, Margaret A.

    1994-03-01

    The classical model of a paradigm shift is used to explore changes that are occurring in public lands and water resources management. Recent policy developments suggest that the traditional paradigm, which is characterized by sustained yield, is in the process of being invalidated. While no new paradigm has been fully accepted, the emerging paradigm does appear to be based on two principles: ecosystem management and collaborative decision making. Implementation of these two principles is likely to require extensive revision of traditional management practices and institutions. Failure to address these issues could result in adoption of the rhetoric of change without any lasting shift in management practices or professional attitudes.

  5. In pursuit of change: Conceptualizing the social work response to LGBTQ microaggressions in health settings.

    Science.gov (United States)

    Kia, Hannah; MacKinnon, Kinnon Ross; Legge, Melissa Marie

    2016-01-01

    Despite the emergence of research on microaggressions targeting lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ) communities in recent years, there remains an insufficiency of theoretical literature in this area. In this article, we draw on the works of Michel Foucault to conceptualize the effects of microaggressive practices on LGBTQ people accessing health and other social services, and generate insight into strategies these groups use to resist these effects. We emphasize the need for social workers, particularly those in health care settings, to support these communities' ongoing attempts at challenging the effects of microaggression, and to this end, outline several implications of our analysis for social work practice.

  6. Structural Change in Advanced Nations : A New Set of Stylised Facts

    NARCIS (Netherlands)

    Jorgenson, D.W.; Timmer, Marcel

    2010-01-01

    We provide new evidence on patterns of structural change in advanced economies, reconsidering the stylised facts put forward by Kaldor (1967), Kuznets (1971) and Maddison (1980). Since 1980 the services sector has overwhelmingly predominated in the economic activity of the European Union, Japan and

  7. Structural Change in Advanced Nations : A New Set of Stylised Facts

    NARCIS (Netherlands)

    Jorgenson, Dale W.; Timmer, Marcel P.

    2011-01-01

    We provide new evidence on patterns of structural change in advanced economies, reconsidering the stylised facts put forward by Kaldor (1963), Kuznets (1971), and Maddison (1980). Since 1980, the services sector has overwhelmingly predominated in the economic activity of the European Union, Japan, a

  8. Computer Anxiety and Performance: An Application of a Change Model in a Pedagogical Setting.

    Science.gov (United States)

    Desai, Mayur S.

    2001-01-01

    Discusses the adverse effects of computer anxiety on student performance and reports an application of a change management process to a class on computers in business that attempted to reduce computer anxiety and improve learning and performance through a pedagogical intervention. Considers implications of results that showed lower anxiety but not…

  9. The Impediments to the Successful Implementation of Change Initiatives in Special Education Settings

    Science.gov (United States)

    Edwards, Erin

    2012-01-01

    As school systems in general and special education programming specifically come under increasing financial and ideological pressure to undergo reform, it is critically important to understand any resistance to change, to identify and describe the culture of resistance that exists within complexity that define our school systems today, and to…

  10. [Change settings for visual analyzer of child users of mobile communication: longitudinal study].

    Science.gov (United States)

    Khorseva, N I; Grigor'ev, Iu G; Gorbunova, N V

    2014-01-01

    The paper represents theresults of longitudinal monitoring of the changes in the parameters of simple visual-motor reaction, the visual acuity and the rate of the visual discrimination in the child users of mobile communication, which indicate the multivariability of the possible effects of radiation from mobile phones on the auditory system of children.

  11. Mineralogical Changes and Fe Valence State During Antigorite Breakdown in Subduction Settings

    Science.gov (United States)

    Merkulova, M.; Munoz, M.; Vidal, O.; Brunet, F.

    2014-12-01

    Mineralogical and petrological changes in subduction zones include transition from altered hydrated rocks (mostly serpentinites) to anhydrous peridotites with the release of fluid. Changes in the valence of iron and other ions capable for electron-exchanges remain poorly constrained during this transition. The approach of this work comprises thermodynamic modeling and experiments based on the use of a piston-cylinder apparatus. We show a series of experiments with the range of temperatures from 550 to 850oC at pressure of 2 GPa, which perform the antigorite dehydration reaction using Fe-bearing antigorite and magnetite as starting material. The experimentally produced mineral phases have been characterized by X-ray diffraction, electron microprobe and X-ray absorption spectroscopy (XANES at the iron K-edge). At each step of serpentinite dehydration reaction we provide the modal abundance of minerals, the amount of releasing water, the chemical compositions of phases and the Fe-oxidation state. The modal abundance of experimental product assemblage changes gradually. Thus, antigorite dominates untill 650 oC and it fully dehydrates after 700 oC. Olivine and enstatite are the most prevailing phases at higher temperatures. However, chlorite, diopside and tremolite are observed during the reaction. Furthermore, olivine and antigorite have been found to change their iron content depending on temperature, which is in consistent with thermodynamic modeling accomplished in the present study. As the reaction progress with the increase of temperature, evolution of iron oxidation state changes. Antigorite containing mostly Fe3+ releases water and breaks down into olivine and enstatite containing Fe2+. The bulk Fe3+/Fetotal ratio decreases rapidly during first steps of the reaction and continue decreasing after antigorite disappearance. In our results we have showed the analyses of Fe valence state in both bulk rocks and separate minerals. Characterizing the evolution of

  12. Task-specific effects of tDCS-induced cortical excitability changes on cognitive and motor sequence set shifting performance.

    Directory of Open Access Journals (Sweden)

    Jorge Leite

    Full Text Available In this study, we tested the effects of transcranial Direct Current Stimulation (tDCS on two set shifting tasks. Set shifting ability is defined as the capacity to switch between mental sets or actions and requires the activation of a distributed neural network. Thirty healthy subjects (fifteen per site received anodal, cathodal and sham stimulation of the dorsolateral prefrontal cortex (DLPFC or the primary motor cortex (M1. We measured set shifting in both cognitive and motor tasks. The results show that both anodal and cathodal single session tDCS can modulate cognitive and motor tasks. However, an interaction was found between task and type of stimulation as anodal tDCS of DLPFC and M1 was found to increase performance in the cognitive task, while cathodal tDCS of DLPFC and M1 had the opposite effect on the motor task. Additionally, tDCS effects seem to be most evident on the speed of changing sets, rather than on reducing the number of errors or increasing the efficacy of irrelevant set filtering.

  13. Series Transmission Line Transformer

    Science.gov (United States)

    Buckles, Robert A.; Booth, Rex; Yen, Boris T.

    2004-06-29

    A series transmission line transformer is set forth which includes two or more of impedance matched sets of at least two transmissions lines such as shielded cables, connected in parallel at one end ans series at the other in a cascading fashion. The cables are wound about a magnetic core. The series transmission line transformer (STLT) which can provide for higher impedance ratios and bandwidths, which is scalable, and which is of simpler design and construction.

  14. Simulated Benefits of Green Infrastructure for Urban Stormwater Management under Climate Change in Different Hydroclimatic and Archetypal Urban Settings

    Science.gov (United States)

    Johnson, T. E.; Butcher, J.; Sarkar, S.; Clark, C.

    2015-12-01

    Climate change could significantly alter the occurrence and management of urban stormwater runoff quantity and quality. Responding to this challenge requires an improved understanding of potential changes together with the effectiveness of management responses for reducing impacts under range of potential future climatic conditions. Traditional gray stormwater infrastructure generally uses single-purpose, hard structures including detention basins and storm sewers to dispose of rainwater. Green infrastructure (GI) uses vegetation and soil to manage rainwater where it falls. GI has been gaining in popularity, and has been shown to provide a number of benefits for adapting to climate change including effects on stormwater quantity, quality and carbon and nutrient biogeochemical cycling. Uncertainty remains, however, due to limited understanding of GI performance in different hydroclimatic and urban settings, and in response to changes in climate. In this study we use simulation modeling to assess the impacts of climate change on both gray (wet ponds) and green infrastructure practices (green roofs, swales, bioretention) in different hydroclimatic and urban settings. Simulations were conducted using RHESSYs, a mechanistic, hydrologic and biogeochemical model, for 36 characteristic urban "archetypes" (AUSs) representing different development patterns and GI practices found in typical U.S. cities. Climate change scenarios are based on dynamically and temporally downscaled, mid-21st century climate model output from the North American Regional Climate Change Assessment Program (NARCCAP). Results suggest altered mass and energy inputs will cause changes in performance of these practices for water quantity, water quality, and carbon sequestration that vary across the country. Infrastructure design should take these potential changes into consideration.

  15. Reassessing changes in diurnal temperature range: A new data set and characterization of data biases

    Science.gov (United States)

    Thorne, P. W.; Menne, M. J.; Williams, C. N.; Rennie, J. J.; Lawrimore, J. H.; Vose, R. S.; Peterson, T. C.; Durre, I.; Davy, R.; Esau, I.; Klein-Tank, A. M. G.; Merlone, A.

    2016-05-01

    It has been a decade since changes in diurnal temperature range (DTR) globally have been assessed in a stand-alone data analysis. The present study takes advantage of substantively improved basic data holdings arising from the International Surface Temperature Initiative's databank effort and applies the National Centers for Environmental Information's automated pairwise homogeneity assessment algorithm to reassess DTR records. It is found that breakpoints are more prevalent in DTR than other temperature elements and that the resulting adjustments have a broader distribution. This strongly implies that there is an overarching tendency, across the global meteorological networks, for nonclimatic artifacts to impart either random or anticorrelated rather than correlated biases in maximum and minimum temperature series. Future homogenization efforts would likely benefit from simultaneous consideration of DTR and maximum and minimum temperatures, in addition to average temperatures. Estimates of change in DTR are relatively insensitive to whether adjustments are calculated directly or inferred from adjustments returned for the maximum and minimum temperature series. The homogenized series exhibit a reduction in DTR since the midtwentieth century globally (-0.044 K/decade). Adjustments serve to approximately halve the long-term global reduction in DTR in the basic "raw" data. Most of the estimated DTR reduction occurred over 1960-1980. In several regions DTR has apparently increased over 1979-2012, while globally it has exhibited very little change (-0.016 K/decade). Estimated changes in DTR are an order of magnitude smaller than in maximum and minimum temperatures, which have both been increasing rapidly on multidecadal timescales (0.186 K/decade and 0.236 K/decade, respectively, since the midtwentieth century).

  16. The proper treatment of language acquisition and change in a population setting.

    Science.gov (United States)

    Niyogi, Partha; Berwick, Robert C

    2009-06-23

    Language acquisition maps linguistic experience, primary linguistic data (PLD), onto linguistic knowledge, a grammar. Classically, computational models of language acquisition assume a single target grammar and one PLD source, the central question being whether the target grammar can be acquired from the PLD. However, real-world learners confront populations with variation, i.e., multiple target grammars and PLDs. Removing this idealization has inspired a new class of population-based language acquisition models. This paper contrasts 2 such models. In the first, iterated learning (IL), each learner receives PLD from one target grammar but different learners can have different targets. In the second, social learning (SL), each learner receives PLD from possibly multiple targets, e.g., from 2 parents. We demonstrate that these 2 models have radically different evolutionary consequences. The IL model is dynamically deficient in 2 key respects. First, the IL model admits only linear dynamics and so cannot describe phase transitions, attested rapid changes in languages over time. Second, the IL model cannot properly describe the stability of languages over time. In contrast, the SL model leads to nonlinear dynamics, bifurcations, and possibly multiple equilibria and so suffices to model both the case of stable language populations, mixtures of more than 1 language, as well as rapid language change. The 2 models also make distinct, empirically testable predictions about language change. Using historical data, we show that the SL model more faithfully replicates the dynamics of the evolution of Middle English.

  17. A quantum molecular similarity analysis of changes in molecular electron density caused by basis set flotation and electric field application

    Science.gov (United States)

    Simon, Sílvia; Duran, Miquel

    1997-08-01

    Quantum molecular similarity (QMS) techniques are used to assess the response of the electron density of various small molecules to application of a static, uniform electric field. Likewise, QMS is used to analyze the changes in electron density generated by the process of floating a basis set. The results obtained show an interrelation between the floating process, the optimum geometry, and the presence of an external field. Cases involving the Le Chatelier principle are discussed, and an insight on the changes of bond critical point properties, self-similarity values and density differences is performed.

  18. Changing U.S. Ocean Policy Can Set a New Direction for Marine Resource Management

    Directory of Open Access Journals (Sweden)

    Andrew A. Rosenberg

    2009-12-01

    Full Text Available A central concept in a new direction for ocean policy in the United States is ecosystem-based management, that is, implementation of management integrated across sectors of human activity to achieve the common goal of conserving the structure and function of marine ecosystems to provide a full suite of ecosystem services. Fisheries are a critical sector of ocean activity that impacts these ecosystems, and fishery management is in urgent need of reform to perform better from a conservation perspective. Here, I suggest some specific changes in perspective for fishery management as part of an overall ecosystem-based approach.

  19. An appreciative inquiry approach to practice improvement and transformative change in health care settings.

    Science.gov (United States)

    Carter, Caroline A; Ruhe, Mary C; Weyer, Sharon; Litaker, David; Fry, Ronald E; Stange, Kurt C

    2007-01-01

    Amid tremendous changes and widespread dissatisfaction with the current health care system, many approaches to improve practice have emerged; however, their effects on quality of care have been disappointing. This article describes the application of a new approach to promote organizational improvement and transformation that is built upon collective goals and personal motivations, invites participation at all levels of the organization and connected community, and taps into latent creativity and energy. The essential elements of the appreciative inquiry (AI) process include identification of an appreciative topic and acting on this theme through 4 steps: Discovery, Dream, Design, and Destiny. We describe each step in detail and provide a case study example, drawn from a composite of practices, to highlight opportunities and challenges that may be encountered in applying AI. AI is a unique process that offers practice members an opportunity to reflect on the existing strengths within the practice, leads them to discover what is important, and builds a collective vision of the preferred future. New approaches such as AI have the potential to transform practices, improve patient care, and enhance individual and group motivation by changing the way participants think about, approach, and envision the future.

  20. Electrocardiographic Changes in Certain Cardiovascular Physiological and Pathological Settings. Impact on Coronary Artery Bypass Grafting

    Directory of Open Access Journals (Sweden)

    Dimitar Simov

    2016-03-01

    Full Text Available Review on electrocardiographic changes provoked by aging, diagnostic tests, cardiac surgery, hemodialysis, diabetes, etc., is the objective of the current material. Several electrocardiographic (ECG parameters that are well known risk markers of arrhythmias, incidental heart failure and sudden cardiac death (SCD are discussed: QRS amplitude, QRS morphology, QRS duration, QRS alternans, T-wave amplitude, T-wave morphology, T-wave alternans, negative T-waves, 3D-spatial angle between maximal QRS and T vectors of the vectorcardiographic loops, ST-segment elevation, QT-interval dispersion, and heart rate. All reviewed parameters are compared with the results on the ECG-alterations, induced by coronary artery bypass grafting (CABG surgery. Two parameters showed an improvement in the patients' condition: QRS-T angle and cardiac autonomic innervation while two others (T-wave alternans and heart rate indicated deterioration. We tend to assume that the deterioration in this early post-operative period is an effect of the post-surgery trauma. We speculate that this effect will fade away in a period of a month and more after surgery, and we intend to conduct such a research in the future. The analysis of ECG's changes will help to better assess the impact of the CABG surgery.

  1. Quantitative changes in sets of proteins as markers of biological response

    Energy Technology Data Exchange (ETDEWEB)

    Giometti, C.S.; Taylor, J.; Gemmell, M.A.; Tollaksen, S.L. (Argonne National Lab., IL (USA)); Lalwani, N.D.; Reddy, J.K. (Northwestern Univ., Chicago, IL (USA))

    1990-01-01

    Exposure to either physical or chemical insults triggers a cascade of bio-chemical events within the target cell. This response requires adjustment within the protein population of the cell, some proteins becoming more abundant (those involved in the cellular response), others less abundant (those not required or counterproductive to the response). Thus, quantitative changes in the global protein population of an exposed biological system may well serve as an indicator of exposure, provided the alterations observed are selective and dose-dependent. In this paper we present results from a study in which liver protein changes induced by exposure of mice to chemicals known to cause peroxisome proliferation and subsequent hepatocellular carcinoma where monitored. Clofibrate, and its chemical analog ciprofibrate, are hypolipidemic drugs. Di-(ethylhexyl)phthalate (DEHP) is a plasticizer used widely in disposable containers for blood products. WY-14643 is a chemical shown to cause hypolipidemic and peroxisome proliferation, similar to clofibrate, ciprofibrate and DEHP, but structurally different from these three chemicals. Thus, two of the four chemicals are structurally similar while the remaining two are very distinct, although all four chemicals cause the same gross biological response. Our results show that although common protein effects are observed in mice exposed to these chemicals, each chemical also causes specific alterations in selective subsets of proteins that could serve as markers of a particular exposure. 13 refs., 4 figs., 1 tab.

  2. Gradient Augmented Level Set Method for Two Phase Flow Simulations with Phase Change

    Science.gov (United States)

    Anumolu, C. R. Lakshman; Trujillo, Mario F.

    2016-11-01

    A sharp interface capturing approach is presented for two-phase flow simulations with phase change. The Gradient Augmented Levelset method is coupled with the two-phase momentum and energy equations to advect the liquid-gas interface and predict heat transfer with phase change. The Ghost Fluid Method (GFM) is adopted for velocity to discretize the advection and diffusion terms in the interfacial region. Furthermore, the GFM is employed to treat the discontinuity in the stress tensor, velocity, and temperature gradient yielding an accurate treatment in handling jump conditions. Thermal convection and diffusion terms are approximated by explicitly identifying the interface location, resulting in a sharp treatment for the energy solution. This sharp treatment is extended to estimate the interfacial mass transfer rate. At the computational cell, a d-cubic Hermite interpolating polynomial is employed to describe the interface location, which is locally fourth-order accurate. This extent of subgrid level description provides an accurate methodology for treating various interfacial processes with a high degree of sharpness. The ability to predict the interface and temperature evolutions accurately is illustrated by comparing numerical results with existing 1D to 3D analytical solutions.

  3. Age-Related Changes of the Ocular Surface: A Hospital Setting-Based Retrospective Study

    Directory of Open Access Journals (Sweden)

    Laura Ottobelli

    2014-01-01

    Full Text Available Purpose. To investigate the effects of age on the prevalence of ocular surface diseases (OSD, adherence to treatment, and recovery rates. Patients and Methods. Retrospective analysis of 3000 clinical records from a first-level general ophthalmology clinic. Patients with OSD were prospectively submitted a questionnaire to assess compliance and recovery rates. Results. OSD prevalence was 10.3%. Patients with OSD were significantly older than patients without it: 67.5±20.3 versus 57.0±22.0 years (P=0.036. No significant difference in season distribution was shown. Dry eye disease (DED represented 58% of OSD; its prevalence increased with age until 80 years old and suddenly decreased thereafter. Asymptomatic DED was 37%. Adherence to treatment in OSD was very high (94%; recovery rates were lower in patients aged 21–40 and 61–80 (resp., 65.5% and 77.8% and this was associated with higher OSDI scores. Tear substitutes represented 50% of all prescribed medications; their use increased with age. Discussion. In a “real-life” low-tech setting, OSD showed a prevalence of 10.3%. DED was the most prevalent disease, and it was asymptomatic in more than 1/3 of cases.

  4. Prostate cancer diagnosis in a resource-poor setting: the changing role of digital rectal examination.

    Science.gov (United States)

    Ahmed, Muhammed

    2011-07-01

    We undertook this study in order to determine the current role of digital rectal examination (DRE) in the diagnosis of prostate cancer in a resource-poor setting. The diagnosis of prostate cancer has been revolutionized by the introduction of prostate-specific antigen (PSA), transrectal ultrasound (TRUS) for biopsy guidance and more efficient biopsy equipment, but they are not readily available in most developing countries. This is a prospective study of 131 patients with suspected prostate cancer based on clinical presentation, DRE and elevated PSA. The presence or absence of cancer was confirmed by biopsy and histologic examination. Patients with screen- or incidentally-detected prostate cancer were excluded. The most common symptom was the development of lower urinary tract symptoms (LUTS). All patients had abnormal DRE and indurated prostate was the most frequent finding (50%). The mean PSA was 33.9 ng/mL: of the 131 patients, 80 (61.1%) had a malignant histology following biopsy, 47 (35.9%) were benign and four (3.0%) were prostate intraepithelial neoplasia (PIN). The low specificity of DRE in the diagnosis of prostate cancer requires that it should be combined with other diagnostic modalities such as PSA and TRUS-guided prostate biopsy. Thus government and health-care providers in resource-poor countries must strive to make these facilities available in order to improve prostate cancer diagnosis.

  5. NASA's Global Change Master Directory: Discover and Access Earth Science Data Sets, Related Data Services, and Climate Diagnostics

    Science.gov (United States)

    Aleman, Alicia; Olsen, Lola; Ritz, Scott; Morahan, Michael; Cepero, Laurel; Stevens, Tyler

    2011-01-01

    NASA's Global Change Master Directory provides the scientific community with the ability to discover, access, and use Earth science data, data-related services, and climate diagnostics worldwide. The GCMD offers descriptions of Earth science data sets using the Directory Interchange Format (DIF) metadata standard; Earth science related data services are described using the Service Entry Resource Format (SERF); and climate visualizations are described using the Climate Diagnostic (CD) standard. The DIF, SERF and CD standards each capture data attributes used to determine whether a data set, service, or climate visualization is relevant to a user's needs. Metadata fields include: title, summary, science keywords, service keywords, data center, data set citation, personnel, instrument, platform, quality, related URL, temporal and spatial coverage, data resolution and distribution information. In addition, nine valuable sets of controlled vocabularies have been developed to assist users in normalizing the search for data descriptions. An update to the GCMD's search functionality is planned to further capitalize on the controlled vocabularies during database queries. By implementing a dynamic keyword "tree", users will have the ability to search for data sets by combining keywords in new ways. This will allow users to conduct more relevant and efficient database searches to support the free exchange and re-use of Earth science data. http://gcmd.nasa.gov/

  6. Sero-epidemiological evaluation of changes in Plasmodium falciparum and Plasmodium vivax transmission patterns over the rainy season in Cambodia

    DEFF Research Database (Denmark)

    Cook, Jackie; Speybroeck, Nico; Sochanta, Tho;

    2012-01-01

    In Cambodia, malaria transmission is low and most cases occur in forested areas. Sero-epidemiological techniques can be used to identify both areas of ongoing transmission and high-risk groups to be targeted by control interventions. This study utilizes repeated cross-sectional data to assess the...

  7. [Studies on the changes of adaptation with children in the dental setting. The relationship between the changes of adaptation and various psychological tests].

    Science.gov (United States)

    Uchida, T; Mukai, Y; Sasa, R

    1991-01-01

    The purpose of this study was to discover the changes in the adaptation of children to the Dental setting, and to discover the relationship between the adaptation, and the personality of the child, the personality of the mother, as well as the relationship between the mother and child. The subjects were 60 two to six year old children and their mothers who visited at the Department of Pedodontics, School of Dentistry, Showa University. The results were as follows: 1) The changes of adaptation were classified in groups of four classes. Four groups: Continuous Adaptability (45.0%) Acquired Adaptability (18.3%) Continuous Inadaptability (16.7%) Extreme Inadaptability (20.0%) 2) The inadaptability groups (Continuous Inadaptability and Extreme Inadaptability) of the two to three year old children did not correlate to the change of adaptation and personality of the child, and the relationship between the mother and child. 3) The extreme inadaptability group with the four year old children showed a connection with the change of adaptation and the various Psychological Tests. Concerning personality, the children showed elements of "dependence" "retrogression" and "maladaptation to school (kindergarten)". Concerning the mother child relationship, there were elements of "anxiety" "dotage" "follow blindly" "disagreement". 4) Nobody showed extreme inadaptability in the group of five to six year old children. Continuous Inadaptability group with the five to six year old children showed scarcely any problems. 5) The Personality of mother did not correlate to the change of adaptation of children in the dental setting.

  8. Causes and temporal changes in nationally collected stillbirth audit data in high-resource settings.

    Science.gov (United States)

    Norris, Tom; Manktelow, Bradley N; Smith, Lucy K; Draper, Elizabeth S

    2017-02-14

    Few high-income countries have an active national programme of stillbirth audit. From the three national programmes identified (UK, New Zealand, and the Netherlands) steady declines in annual stillbirth rates have been observed over the audit period between 1993 and 2014. Unexplained stillbirth remains the largest group in the classification of stillbirths, with a decline in intrapartum-related stillbirths, which could represent improvements in intrapartum care. All three national audits of stillbirths suggest that up to half of all reviewed stillbirths have elements of care that failed to follow standards and guidance. Variation in the classification of stillbirth, cause of death and frequency of risk factor groups limit our ability to draw meaningful conclusions as to the true scale of the burden and the changing epidemiology of stillbirths in high-income countries. International standardization of these would facilitate direct comparisons between countries. The observed declines in stillbirth rates over the period of perinatal audit, a possible consequence of recommendations for improved antenatal care, should serve to incentivise other countries to implement similar audit programmes.

  9. Persistent Chaos of Measles Epidemics in the Prevaccination United States Caused by a Small Change in Seasonal Transmission Patterns.

    Directory of Open Access Journals (Sweden)

    Benjamin D Dalziel

    2016-02-01

    Full Text Available Epidemics of infectious diseases often occur in predictable limit cycles. Theory suggests these cycles can be disrupted by high amplitude seasonal fluctuations in transmission rates, resulting in deterministic chaos. However, persistent deterministic chaos has never been observed, in part because sufficiently large oscillations in transmission rates are uncommon. Where they do occur, the resulting deep epidemic troughs break the chain of transmission, leading to epidemic extinction, even in large cities. Here we demonstrate a new path to locally persistent chaotic epidemics via subtle shifts in seasonal patterns of transmission, rather than through high-amplitude fluctuations in transmission rates. We base our analysis on a comparison of measles incidence in 80 major cities in the prevaccination era United States and United Kingdom. Unlike the regular limit cycles seen in the UK, measles cycles in US cities consistently exhibit spontaneous shifts in epidemic periodicity resulting in chaotic patterns. We show that these patterns were driven by small systematic differences between countries in the duration of the summer period of low transmission. This example demonstrates empirically that small perturbations in disease transmission patterns can fundamentally alter the regularity and spatiotemporal coherence of epidemics.

  10. Negative effects of land-use changes in the karst setting of Apulia, southern Italy

    Science.gov (United States)

    Parise, Mario

    2010-05-01

    machineries, and favoured by discutable policy of subsidies from the European Community, stone clearing was intensively performed. Wide sectors of Apulia were affected by land use changes, resulting in destruction of the epikarst (Williams, 2008), and of the karst ecosystems therein present as well, through removal of the stones, even of large size, crushing and production of a gravel-size field where to establish crops such as wheat or vineyards. Loss of the natural karst landscape had therefore to be registered over wide territories in the region (Parise & Pascali, 2003). In addition, removal of the original soil had as direct consequence an increase in the erosional processes on the occasion of the main rainstorms, even at those sites characterized by low to very low gradients. Stones of larger size were often piled near cave entrances, or dumped into caves and swallow holes, thus producing a serious danger to cavers, and sometimes impeding the access to important karst caves. All the above changes resulted in heavy degradation of karst, and especially promoted severe erosion in many areas of the region. In some cases, formation of erosional features combined to persistent droughts, thus developing a tendency toward desertification (Sharma, 1998), as already observed in other areas of the Mediterranean basin (Yair, 1983; Atalay, 1999; Geeson et alii, 2002). References Atalay I. (1999) Land use in the karstic lands in the Mediterranean region. Int. J. Speleol., vol. 26B(1/4), p. 111-118. Geeson N.A., Brandt C.J. & Thornes J.B. (Eds.) (2002) Mediterranean desertification. John Wiley & Sons, 440 pp. Parise M. & Pascali V. (2003) Surface and subsurface environmental degradation in the karst of Apulia (southern Italy). Environmental Geology, vol. 44, p. 247-256. Sharma K.D. (1998) The hydrologic indicators of desertification. J. Arid Environ., vol. 39, p. 121-132. Williams P.W. (2008) The role of the epikarst in karst and cave hydrogeology: a review. International Journal of

  11. Scale up use of family planning services to prevent maternal transmission of HIV among discordant couples: a cross-sectional study within a resource-limited setting

    Directory of Open Access Journals (Sweden)

    Kuete M

    2016-10-01

    Full Text Available Martin Kuete,1,2 HongFang Yuan,1 Aude Laure Tchoua Kemayou,2 Emmanuel Ancel Songo,2 Fan Yang,1 XiuLan Ma,1 ChengLiang Xiong,1 HuiPing Zhang1 1Obstetrics and Gynecology, Reproductive Center, Family Planning and Research Institute, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Main Maternity of Obstetrics and Gynecology, Yaounde Central Hospital, Faculty of Medicine and Biomedical Sciences, Yaounde, Cameroon Background: Integration of family planning services (FPS into human immunodeficiency virus (HIV care for HIV-infected women is an important aspect of the global prevention of mother-to-child transmission (PMTCT strategy. We assessed the integration of FPS into routine care of HIV-infected mothers by evaluating the uptake and barriers of contraception and PMTCT services. Methods: We conducted an interventional study using the interrupted time series approach in the health care facilities located in Yaounde, Cameroon. First, structured questionnaires related to family planning use, PMTCT services use, and infection risk of the sexual partner were administered to the first trimester pregnant women who were HIV infected and living with uninfected partners. Second, 2 weeks before the delivery date, the women were interviewed according to the prior counseling interventions received, in order to assess their behavior on FPS, antiretroviral therapy (ART use, delivery option, and infant nourishment to be adopted. P-values below 0.05 were considered statistically significant in the statistical analyses. Results: Of 94 HIV-infected women, 69% were stable couples. Only 13% of women had attended FPS before conception. Although the vast majority were knowledgeable about modern and traditional contraception methods, only 19% had experienced effective contraceptive methods. However, 66% preferred condom use, 45% having three children still expressed a desire to conceive, while 44% reported

  12. Modeling approaches to detect land-use changes: Urbanization analyzed on a set of 43 US catchments

    Science.gov (United States)

    Salavati, Bahar; Oudin, Ludovic; Furusho-Percot, Carina; Ribstein, Pierre

    2016-07-01

    Paired catchment approach probably provides the most robust method to detect the effects of land-use change on catchments' flow characteristics. This approach is limited by the availability of two neighbor catchments with and without land-use change under similar climate conditions. This paper uses a hydrological model to detect the hydrological change caused by urbanization. This study describes (1) use a statistical method to evaluate change detection relative to variation of land use change, (2) simulation of non-urban condition for the urban catchment with an alternative approach, to this aim stream flow series of urban catchments have been reconstructed from the period that urbanization had not taken place yet, and (3) the model validation with observed data. This paper intends to compare the flow changes detected by two different approaches: a regional statistical approach (the paired-catchment approach) and a conceptual modeling approach (the residual approach) on the particular case of urbanized catchments. To investigate the sensitivity of the results to the settings of both approaches, the comparison is made on a relatively large number of 43 catchments located in the United States, with relatively large gradients in terms of geomorphology and hydroclimatic characteristics. Results show that the two approaches are generally in relative good agreement in terms of detection and quantification of changes for the three flow characteristics analyzed (mean annual flow, high and low flow characteristics). Besides, it is found that the impact of urbanization on the catchment's hydrologic response is difficult to generalize: the proportion of nonsignificant trends, significantly increasing decreasing trends are on the same order of magnitude, even if an increase in urban areas generally has a greater impact on mean flows and high flows than on low flows.

  13. A Calculation Method of Grounding-Distance Protection Setting for Transmission Lines with Double-Branched Structure%双分叉线路的接地距离保护整定计算

    Institute of Scientific and Technical Information of China (English)

    文安; 王聪; 李建设; 于芮技; 莫天文; 魏承志; 寻斌斌; 李银红

    2014-01-01

    双分叉线路是输电线路增容改建工程中产生的一种特殊结构线路。可以增大线路输送容量,提高走廊利用率,并且节约建设投资,缩短工期,停电时间较短。从双分叉线路结构特点和保护原理入手,分析了双分叉结构对继电保护整定计算的影响。分析表明,对于双分叉线路,采用改建后线路的实际测量参数,或根据原线路参数计算得到的修正参数,及时调整零序补偿系数中的相应一次值,然后按简单线路整定方法进行整定即可,不会造成保护玉段超越误动。为继电保护整定计算工作提供了依据。%Double-branched transmission line is a special structure in the extension and reconstruction of transmission lines.It can be used to increase the capacity of transmission lines, improve transmission corridors' use efficiency, save cost, shorten construction pe-riod and outage time.A model for double-branched lines has been established based on its structure, and on this basis, effect of the double branched structure to selectivity of ground distance protection has been discussed.The analysis shows that, for transmission lines with double-branched structure, it only needs to calculate zero-sequence compensating coefficient with the correct actual meas-ured value of the newly structured lines or the adjusted parameters, that can get reasonable setting values in the light of the original setting calculation method for usual lines.It provides more reasonable principles when determining the grounding distance protection settings.

  14. Electrical Set-Reset Phenomenon in Thallium Doped Ge-Te Glasses Suitable for Phase Change Memory Applications

    Directory of Open Access Journals (Sweden)

    M.M. Rahman

    2011-01-01

    Full Text Available Ge17Te83-xTlx (x = 2, 3, 6, 8, 10 glasses have been prepared by melt quenching method and their amorphous nature was confirmed by XRD spectra. I-V characteristics and repeatability of electrical switching were investigated for all the glasses in order to find out their suitability for phase change memory applications. A comparison has been given with Ge2Sb2Te5 the most commonly used material for phase change memory application. The entire series of glasses exhibited memory type of electrical switching but only the composition Ge17Te81Tl2 was able to withstand SET-RESET pulses for more than 10 cycles. The other samples show repeatability for only a few cycles with the degradation of threshold voltage.

  15. Examining change in cortisol patterns during the 10-week transition to a new child-care setting.

    Science.gov (United States)

    Bernard, Kristin; Peloso, Elizabeth; Laurenceau, Jean-Philippe; Zhang, Zhiyong; Dozier, Mary

    2015-01-01

    The transition to out-of-home child care brings a number of challenges for children, including complex peer interactions and extended separations from parents. Children often show a midmorning to afternoon rise in cortisol on child-care days, compared to the typical diurnal decline seen at home. Changes in cortisol were examined in a wide age range of children (N = 168; 1.2 months to 8 years, M = 3.27 years) during the 10-week transition to a new child-care setting. Structural equation modeling using latent change scores showed that children experienced an increase in the cortisol rise at child care across the 10-week transition. Furthermore, child age moderated the difference between home- and child-care cortisol patterns. Findings are placed in a developmental context, and potential implications and future directions are discussed.

  16. Defining falciparum malaria attributable sever febrile illness in moderate to high transmission settings based on plasma PfHRP2 concentration

    NARCIS (Netherlands)

    Hendriksen, I.C.E.; White, L.J.; Veenemans, J.; Verhoef, J.C.M.

    2013-01-01

    Background. In malaria-endemic settings, asymptomatic parasitemia complicates the diagnosis of malaria. Histidine-rich protein 2 (HRP2) is produced by Plasmodium falciparum, and its plasma concentration reflects the total body parasite burden. We aimed to define the malaria-attributable fraction of

  17. What's in an elevation difference? Accuracy and corrections of satellite elevation data sets for quantification of glacier changes

    Directory of Open Access Journals (Sweden)

    C. Nuth

    2010-10-01

    Full Text Available There is an increasing number of DEMs available worldwide for deriving elevation differences over time, including vertical changes on glaciers. Most of these DEMs are heavily post-processed or merged, so that physical error modelling becomes impossible and statistical error modelling is required instead. We propose a three-step methodological framework for assessing and correcting DEMs to quantify glacier elevation changes: remove DEM shifts, check for elevation-dependent biases, and check for higher-order, sensor-specific biases. An analytic, simple and robust method to co-register elevation data is presented in regions where stable terrain is either plentiful (case study New Zealand or limited (case study Svalbard. The method is exemplified using the three global elevation data sets available, SRTM, ICESat and the ASTER GDEM, and with automatically generated DEMs from satellite stereo instruments of ASTER and SPOT5-HRS. After three-dimensional co-registration, significant biases related to elevation were found in some of the stereoscopic DEMs. Biases related to the satellite acquisition geometry (along/cross track were detected at two frequencies in the automatically generated ASTER DEMs. The higher frequency bias seems to be related to satellite emph{jitter}, most effective in the back-looking pass of the satellite. The origins of the more significant lower frequency bias is uncertain. ICESat-derived elevations are found to be the most consistent globally available elevation data set available so far. Before performing regional-scale glacier elevation change studies or mosaicking DEMs from multiple individual tiles (e.g. ASTER GDEM, we recommend to co-register all elevation data to ICESat as a global vertical reference system. The proposed methodological framework is exemplified for elevation changes on the Fox, Franz Joseph, Tasman and Murchison glaciers of New Zealand and the glaciers of central Spitsbergen, Svalbard.

  18. Echographic and Kinetic Changes in the Shoulder Joint after Manual Wheelchair Propulsion Under Two Different Workload Settings

    Science.gov (United States)

    Gil-Agudo, Ángel; Solís-Mozos, Marta; Crespo-Ruiz, Beatriz; del-Ama Eng, Antonio J.; Pérez-Rizo, Enrique; Segura-Fragoso, Antonio; Jiménez-Díaz, Fernando

    2014-01-01

    Manual wheelchair users with spinal cord injury (SCI) have a high prevalence of shoulder pain due to the use of the upper extremity for independent mobility, transfers, and other activities of daily living. Indeed, shoulder pain dramatically affects quality of life of these individuals. There is limited evidence obtained through radiographic techniques of a relationship between the forces acting on the shoulder during different propulsion conditions and shoulder pathologies. Today, ultrasound is widely accepted as a precise tool in diagnosis, displaying particularly effectiveness in screening the shoulder rotator cuff. Thus, we set out to perform an ultrasound-based study of the acute changes to the shoulder soft tissues after propelling a manual wheelchair in two workload settings. Shoulder joint kinetics was recorded from 14 manual wheelchair users with SCI while they performed high- and low-intensity wheelchair propulsion tests (constant and incremental). Shoulder joint forces and moments were obtained from inverse dynamic methods, and ultrasound screening of the shoulder was performed before and immediately after the test. Kinetic changes were more relevant after the most intensive task, showing the significance of high-intensity activity, yet no differences were found in ultrasound-related parameters before and after each propulsion task. It therefore appears that further studies will be needed to collect clinical data and correlate data regarding shoulder pain with both ultrasound images and data from shoulder kinetics. PMID:25566539

  19. ECHOGRAPHIC AND KINETIC CHANGES IN THE SHOULDER JOINT AFTER MANUAL WHEELCHAIR PROPULSION UNDER TWO DIFFERENT WORKLOAD SETTINGS

    Directory of Open Access Journals (Sweden)

    Ángel eGil-Agudo

    2014-12-01

    Full Text Available AbstractManual wheelchair users with spinal cord injury have a high prevalence of shoulder pain, due to the use of the upper extremity for independent mobility, transfers and other activities of daily living. Indeed, shoulder pain dramatically affects quality of life of these individuals. There is limited evidence obtained through radiographic techniques of a relationship between the forces acting on the shoulder during different propulsion conditions and shoulder pathologies. Today, ultrasound is widely accepted as a precise tool in diagnosis, displaying particularly effectiveness in screening the shoulder rotator cuff. Thus, we set out to perform an ultrasound-based study of the acute changes to the shoulder soft tissues after propelling a manual wheelchair in two workload settings. Shoulder joint kinetics was recorded from 14 manual wheelchair users with spinal cord injury while they performed high and low intensity wheelchair propulsion tests (constant and incremental. Shoulder joint forces and moments were obtained from inverse dynamic methods, and ultrasound screening of the shoulder was performed before and immediately after the test. Kinetic changes were more relevant after the most intensive task, showing the significance of high intensity activity, yet no differences were found in ultrasound-related parameters before and after each propulsion task. It therefore appears that further studies will be needed to collect clinical data and correlate data regarding shoulder pain with both ultrasound images and data from shoulder kinetics.

  20. Scale up use of family planning services to prevent maternal transmission of HIV among discordant couples: a cross-sectional study within a resource-limited setting

    Science.gov (United States)

    Kuete, Martin; Yuan, HongFang; Tchoua Kemayou, Aude Laure; Songo, Emmanuel Ancel; Yang, Fan; Ma, XiuLan; Xiong, ChengLiang; Zhang, HuiPing

    2016-01-01

    Background Integration of family planning services (FPS) into human immunodeficiency virus (HIV) care for HIV-infected women is an important aspect of the global prevention of mother-to-child transmission (PMTCT) strategy. We assessed the integration of FPS into routine care of HIV-infected mothers by evaluating the uptake and barriers of contraception and PMTCT services. Methods We conducted an interventional study using the interrupted time series approach in the health care facilities located in Yaounde, Cameroon. First, structured questionnaires related to family planning use, PMTCT services use, and infection risk of the sexual partner were administered to the first trimester pregnant women who were HIV infected and living with uninfected partners. Second, 2 weeks before the delivery date, the women were interviewed according to the prior counseling interventions received, in order to assess their behavior on FPS, antiretroviral therapy (ART) use, delivery option, and infant nourishment to be adopted. P-values below 0.05 were considered statistically significant in the statistical analyses. Results Of 94 HIV-infected women, 69% were stable couples. Only 13% of women had attended FPS before conception. Although the vast majority were knowledgeable about modern and traditional contraception methods, only 19% had experienced effective contraceptive methods. However, 66% preferred condom use, 45% having three children still expressed a desire to conceive, while 44% reported abortions, 65% had tried to avoid the current pregnancy, and 12% of women were ART naïve. Several predictors such as education, abortion rate, unplanned pregnancies, and partners’ decision were associated with the nonuse of effective contraceptive methods. Moreover, barriers including sex inequity, lack of partner support, ART shortages, and lack of HIV viral load monitoring were prevalent among the participants (P=0.001). However FPS use, ART compliance, and safe options to PMTCT

  1. High HIV incidence in the postpartum period sustains vertical transmission in settings with generalized epidemics: a cohort study in Southern Mozambique

    Directory of Open Access Journals (Sweden)

    Caroline De Schacht

    2014-03-01

    Full Text Available Introduction: Acute infection with HIV in the postpartum period results in a high risk of vertical transmission through breastfeeding. A study was done to determine the HIV incidence rate and associated risk factors among postpartum women in Southern Mozambique, where HIV prevalence among pregnant women is 21%. Methods: A prospective cohort study was conducted in six rural health facilities in Gaza and Maputo provinces from March 2008 to July 2011. A total of 1221 women who were HIV-negative on testing at delivery or within two months postpartum were recruited and followed until 18 months postpartum. HIV testing, collection of dried blood spot samples and administration of a structured questionnaire to women were performed every three months. Infant testing by DNA-PCR was done as soon as possible after identification of a new infection in women. HIV incidence was estimated, and potential risk factors at baseline were compared using Poisson regression. Results: Data from 957 women were analyzed with follow-up after the enrolment visit, with a median follow-up of 18.2 months. The HIV incidence in postpartum women is estimated at 3.20/100 women-years (95% CI: 2.30–4.46, with the highest rate among 18- to 19-year-olds (4.92 per 100 women-years; 95% CI: 2.65–9.15. Of the new infections, 14 (34% were identified during the first six months postpartum, 11 (27% between 6 and 12 months and 16 (39% between 12 and 18 months postpartum. Risk factors for incident HIV infection include young age, low number of children, higher education level of the woman's partner and having had sex with someone other than one's partner. The vertical transmission was 21% (95% CI: 5–36 among newly infected women. Conclusions: Incidence of HIV is high among breastfeeding women in Southern Mozambique, contributing to increasing numbers of HIV-infected infants. Comprehensive primary prevention strategies targeting women of reproductive age, particularly pregnant and

  2. The cost of changing physical activity behaviour: evidence from a "physical activity pathway" in the primary care setting

    Directory of Open Access Journals (Sweden)

    Bull Fiona C

    2011-05-01

    Full Text Available Abstract Background The 'Physical Activity Care Pathway' (a Pilot for the 'Let's Get Moving' policy is a systematic approach to integrating physical activity promotion into the primary care setting. It combines several methods reported to support behavioural change, including brief interventions, motivational interviewing, goal setting, providing written resources, and follow-up support. This paper compares costs falling on the UK National Health Service (NHS of implementing the care pathway using two different recruitment strategies and provides initial insights into the cost of changing physical activity behaviour. Methods A combination of a time driven variant of activity based costing, audit data through EMIS and a survey of practice managers provided patient-level cost data for 411 screened individuals. Self reported physical activity data of 70 people completing the care pathway at three month was compared with baseline using a regression based 'difference in differences' approach. Deterministic and probabilistic sensitivity analyses in combination with hypothesis testing were used to judge how robust findings are to key assumptions and to assess the uncertainty around estimates of the cost of changing physical activity behaviour. Results It cost £53 (SD 7.8 per patient completing the PACP in opportunistic centres and £191 (SD 39 at disease register sites. The completer rate was higher in disease register centres (27.3% vs. 16.2% and the difference in differences in time spent on physical activity was 81.32 (SE 17.16 minutes/week in patients completing the PACP; so that the incremental cost of converting one sedentary adult to an 'active state' of 150 minutes of moderate intensity physical activity per week amounts to £ 886.50 in disease register practices, compared to opportunistic screening. Conclusions Disease register screening is more costly than opportunistic patient recruitment. However, additional costs come with a higher

  3. Impact of anthropogenic and natural environmental changes on Echinococcus transmission in Ningxia Hui Autonomous Region, the People’s Republic of China

    Directory of Open Access Journals (Sweden)

    Yang Yu

    2012-07-01

    Full Text Available Abstract Echinococcus transmission is known to be affected by various environmental factors, which may be modified by human influence or natural events including global warming. Considerable population growth in the last fifty years in Ningxia Hui Autonomous Region (NHAR, the People’s Republic of China (PRC, has led to dramatic increases in deforestation and modified agricultural practices. In turn, this has resulted in many changes in the habitats for the definitive and intermediate hosts of both Echinococcus granulosus and E. multilocularis, which have increased the risks for transmission of both parasites, affecting echinococcosis prevalence and human disease. Ecological environmental changes due to anthropogenic activities and natural events drive Echinococcus transmission and NHAR provides a notable example illustrating how human activity can impact on a parasitic infection of major public health significance. It is very important to continually monitor these environmental (including climatic factors that drive the distribution of Echinococcus spp. and their impact on transmission to humans because such information is necessary to formulate reliable future public health policy for echinococcosis control programs and to prevent disease spread.

  4. Kansas Electric Transmission Lines

    Data.gov (United States)

    Kansas Data Access and Support Center — This data set is a digital representation of the EletcircTransmission lines for the State of Kansas as maintained by the Kansas Corporation Commission. Data is...

  5. Outbreak of a new measles B3 variant in the Roma/Sinti population with transmission in the nosocomial setting, Italy, November 2015 to April 2016.

    Science.gov (United States)

    Filia, Antonietta; Amendola, Antonella; Faccini, Marino; Del Manso, Martina; Senatore, Sabrina; Bianchi, Silvia; Borrini, Bianca Maria; Ciampelli, Alessio; Tanzi, Elisabetta; Filipponi, Maria Teresa; Piccirilli, Giulia; Lazzarotto, Tiziana; Pascucci, Maria Grazia; Baggieri, Melissa; Magurano, Fabio

    2016-05-19

    A measles outbreak occurred from November 2015 to April 2016 in two northern Italian regions, affecting the Roma/Sinti ethnic population and nosocomial setting. Overall, 67 cases were reported. Median age of 43 cases in three Roma/Sinti camps was four years, nosocomial cases were mainly adults. The outbreak was caused by a new measles virus B3.1 variant. Immunisation resources and strategies should be directed at groups with gaps in vaccine coverage, e.g. Roma/Sinti and healthcare workers.

  6. 轧机换辊车传动方式改进设计%Improvement Design for the Transmission Mode of the Roll Change Carriage in Rolling Mill

    Institute of Scientific and Technical Information of China (English)

    王华勇; 周晓艳

    2013-01-01

    The defects of the old transmission mode is analyzed ,the force analysis of the gear in reduction box is analyzed and the troque of the old mode is calculated .According to these analysis,the old transmission mode should be changed to hydraulic motor.It is proved that this improvement could reduce the failure rate and shorten the roll changing time effectively.%针对换辊车原设计传动方式的不足,改变原有传动方式,通过对减速箱齿轮的受力分析,计算出原传动所提供的扭矩,将减速电机更换为液压马达,生产实践证明,此改进可降低设备故障率,缩短换辊时间。

  7. Meta-analysis of differentiating mouse embryonic stem cell gene expression kinetics reveals early change of a small gene set.

    Directory of Open Access Journals (Sweden)

    Clive H Glover

    2006-11-01

    Full Text Available Stem cell differentiation involves critical changes in gene expression. Identification of these should provide endpoints useful for optimizing stem cell propagation as well as potential clues about mechanisms governing stem cell maintenance. Here we describe the results of a new meta-analysis methodology applied to multiple gene expression datasets from three mouse embryonic stem cell (ESC lines obtained at specific time points during the course of their differentiation into various lineages. We developed methods to identify genes with expression changes that correlated with the altered frequency of functionally defined, undifferentiated ESC in culture. In each dataset, we computed a novel statistical confidence measure for every gene which captured the certainty that a particular gene exhibited an expression pattern of interest within that dataset. This permitted a joint analysis of the datasets, despite the different experimental designs. Using a ranking scheme that favored genes exhibiting patterns of interest, we focused on the top 88 genes whose expression was consistently changed when ESC were induced to differentiate. Seven of these (103728_at, 8430410A17Rik, Klf2, Nr0b1, Sox2, Tcl1, and Zfp42 showed a rapid decrease in expression concurrent with a decrease in frequency of undifferentiated cells and remained predictive when evaluated in additional maintenance and differentiating protocols. Through a novel meta-analysis, this study identifies a small set of genes whose expression is useful for identifying changes in stem cell frequencies in cultures of mouse ESC. The methods and findings have broader applicability to understanding the regulation of self-renewal of other stem cell types.

  8. Studies on Clinical Aspects, Pathological Changes, Immunohistochemistry, 14-3-3 protein, PrP Gene, and Animal Transmission of Creutzldt-Jakob Disease in China

    Institute of Scientific and Technical Information of China (English)

    Lin Shilie; Zhao Jiexu; Jiang Xinmei; Song Xiaonan; Wang Weimin; Fan Yengyeng; Tao Yuiqin; Chen Xiuyun

    2000-01-01

    Objectives To investigate the clinical manifestations, pathological changes, expression of PrP gene, 14-3-3 protein in cerebrospinal fluid (CSF) and experimental animal transmission of Creuizfeldt-Jakob disease (CJD) in China. Methods Clinical aspects of 24 patients with CJD which was confirmed neuropathological were evaluated. Brain sections of 10 cases of them were given immunostaining with antiserum to a synthetic polypeptide of prioni protein (PrP). PrP gene was analyzed in 10 cases, and 14-3-3 protein in CSF was detected in 5 cases. Experimental mouse transmission was carried out using brain suspension from 7 patients with CJD. Results 1) Nineteen cases with sporadic CJD, 3 cases with iatrogenic CJD, 1 case with inherited CJD and 1 case with coexistence of Alzheimer disease(AD) and CJD were found. 2) The percentage of acute and subacute onset was high up to 96%. The illness duration was shorter in a subacute onset and the brain atrophy was not obvious.3) The synaptic type of PrP deposition was shown in paraffin sections in all -cases by immunostaining.4) 14-3-3 protein was detected in 5 eases in cerebrospinal fluid with CJD 5) Spongiform degeneration and PrP deposition could be shown in the brain sections of experimental mouse transmission. Conclusion There are special characteristics in clinical aspects of CJD in China. The detection of 14-3-3 protein can provide objective evidence for early diagnosis of CJD in order to prevent its transmission

  9. Effects of a healthy food supply intervention in a military setting: positive changes in cereal, fat and sugar containing foods

    Directory of Open Access Journals (Sweden)

    Bingham Clarissa ML

    2012-07-01

    Full Text Available Abstract Background In Finland, all men are liable to military service and a clear majority completes service. The increasing prevalence of obesity also among soldiers concerns conscripts’ food choices. Conscripts are served nutritionally planned regular main meals but individual choices take place in free-time eating. This study assesses the effects in conscripts’ eating habits in an intervention targeting the supply of healthy foods available in the military setting. Methods Participants were 604 18-21-year old male conscripts of whom 242 belonged to Control Group and 362 to Intervention Group. Participants of Control Group were historical controls performing military service one year before Intervention Group. The intervention targeted selection, placement, and attractiveness of healthy foods in garrison refectories and soldier’s home cafeterias, the two main food providers in the military. Dietary intake data was collected by self-administered questionnaire at three time points: before/beginning of military service (T0, 8 weeks (T1 and 6 months (T2 of military service. Outcome measures were food consumption frequencies and four dietary indexes (Cereal Index, Fruit and Vegetable Index, Fat Index and Sugar Index developed to characterize the diet. Changes between study groups in outcome variables and in time were analysed by repeated-measures analysis of covariance. Results Significant (p  Conclusions In the military setting, healthier food choices can be promoted by intervening on the main food environments by improving the supply of healthy foods. However, impacting on conscripts’ individual selection as fruit and vegetable consumption is more challenging.

  10. Baseline survey of pregnant women 's knowledge of treat-ment to prevent mother-to-child human immuno-deficien-cy virus transmission in a resource limited setting

    Institute of Scientific and Technical Information of China (English)

    Stephen Onwere; Obioha Okoro; Bright Chigbu; Chuks Kamanu; Christian Aluka; Paul Feyi-Wa-boso

    2008-01-01

    Despite continuing advances in scientific knowledge about treatments to prevent mother-to-child (MTCT)of the human immune deficiency virus (HIV),there is a paucity of data on pregnant women's knowledge of treat-ments to prevent MTCT of HIV in Aba,South Eastern Nigeria.We investigated pregnant women's knowledge of the availability of treatments to prevent MTCT of HIV in the low resourced setting of Aba town in South Eastern Nigeria.A descriptive study involving 100 consecutive and consenting patients at the antenatal clinic of Abia State University Teaching Hospital (ABSUTH),Aba,South Eastern Nigeria over the period 1st November, 2007 to 30th November,2007.Using a structured questionnaire,the respondents'sociodemographic data were obtained as well as their knowledge of the availability of treatments to prevent mother to child HIV transmission in pregnant women and self-reported data on their having ever tested for HIV.Knowledge regarding availability of treatment to prevent mother to child transmission of HIV was good as 95% of the respondents were aware that such treatment was available.Knowledge that treatment is available to help someone infected by HIV to live longer was also good as 96% of the respondents were aware of the availability of such treatment.Seventy one percent of the respondents had ever tested for HIV.The levels of knowledge regarding the availability of treatment to prevent mother to child HIV transmission and to help someone infected with HIV are good.Thus, utilization of anti-retroviral prophylaxis amongst HIV infected pregnant women in this community would be ex-pected to be high if the drugs were available.This will reduce the impact of HIV,especially in children.

  11. Goal setting and lifestyle changes in a nurse-led counselling programme for leg ulcer patients: an explorative analysis of nursing records.

    NARCIS (Netherlands)

    Glind, I.M. van de; Heinen, M.M.; Evers, A.W.; Achterberg, T. van

    2015-01-01

    AIMS AND OBJECTIVES: To describe goals set in individual nurse-led lifestyle counselling sessions in leg ulcer patients, and to explore patient and goal characteristics in relation to health behaviour change. BACKGROUND: Goal setting is increasingly used in nurse-led counselling programmes, but the

  12. Poverty and price transmission

    DEFF Research Database (Denmark)

    Elleby, Christian

    A key parameter determining the welfare impact from a world market shock is the transmission elasticity which measures the average domestic response to an international price change. Many studies have estimated price transmission elasticities for a large number of countries but the variation in t...

  13. Taphonomy of deciduous leaves and changes in the d13C signal after deposition in fresh water settings

    Science.gov (United States)

    Reimann, Simon; Roth-Nebelsick, Anita; Nebelsick, James; Grein, Michaela

    2016-04-01

    Carbon isotopic signals from fossil plant material are an important source of information for palaeoecology and palaeoclimatology. Usually, the 13C isotope is depleted in plant material, compared to the atmospheric 13C content, because 13C is discriminated against 12C during the process of photosynthesis. The degree of 13C discrimination depends on the photosynthetic pathway (C3, C4 and CAM) and is substantially affected by environmental factors (for example, water stress). Various plant material components, however, differ also with respect to their 13C content. It is generally assumed that the d13C signal found in fossil plants reflects that of the living plant to a sufficient degree. Obtaining information on possible alterations during the taphonomic process is, however, desirable. In this study, changes in d13C of deciduous leaves are monitored, from the living leaf still attached to the tree to leaves deposited in fresh water setting for one or more years, thus focusing on early stages of taphonomy. The considered taxa are species from Quercus (oak) and Fagus (beech). Deposited leaves from three fresh water environments in Southwestern Germany were studied: active stream in a forest, still water pond in a forest, and a waterlogged moor environment. Additionally to the isotope measurements, the degree of leaf tissue degradation and colonization with degrading organisms were observed with Scanning Electron Microscopy.

  14. Resistance to changing practice from pro re nata prescriptions to patient group directions in acute mental health settings.

    Science.gov (United States)

    Price, O; Baker, J A

    2013-09-01

    Poor practice associated with pro re nata (PRN) prescriptions in mental health is known to be common and can increase the risk of serious and potentially fatal side effects. A contributing factor to poor practice is the lack of a clear chain of accountability between the decision to prescribe and administer PRN prescriptions. To address this problem, a patient group direction (PGD) for acute behavioural disturbance (lorazepam 0.5-2 mg) and staff training materials were developed. The intention was to replace PRN prescriptions with the PGD in two mental health trusts. One of the potential benefits of this would be the removal of the contribution of PRN to high and combined dose antipsychotic prescriptions. This proposal, however, was met with significant resistance in both trusts and did not replace PRN as a result. A series of interviews and focus groups were conducted with 16 RMNs working in the two trusts, to explore the reasons why the PGD was met with resistance. Senior nurses perceived resistance to be associated with anxieties over increased responsibility for decision making. Junior nurses reported concerns regarding the medicalization of the nursing role, the paperwork associated with the PGD and the training approach used. Future efforts to implement PGDs in mental health settings must carefully consider the methods for engaging effectively with participating organizations, in terms of managing change and completing the necessary groundwork for successful implementation.

  15. Cardiometabolic Risk Factor Changes Observed in Diabetes Prevention Programs in US Settings: A Systematic Review and Meta-analysis.

    Directory of Open Access Journals (Sweden)

    Uma Mudaliar

    2016-07-01

    Full Text Available The Diabetes Prevention Program (DPP study showed that weight loss in high-risk adults lowered diabetes incidence and cardiovascular disease risk. No prior analyses have aggregated weight and cardiometabolic risk factor changes observed in studies implementing DPP interventions in nonresearch settings in the United States.In this systematic review and meta-analysis, we pooled data from studies in the United States implementing DPP lifestyle modification programs (focused on modest [5%-7%] weight loss through ≥150 min of moderate physical activity per week and restriction of fat intake in clinical, community, and online settings. We reported aggregated pre- and post-intervention weight and cardiometabolic risk factor changes (fasting blood glucose [FBG], glycosylated hemoglobin [HbA1c], systolic or diastolic blood pressure [SBP/DBP], total [TC] or HDL-cholesterol. We searched the MEDLINE, EMBASE, Cochrane Library, and Clinicaltrials.gov databases from January 1, 2003, to May 1, 2016. Two reviewers independently evaluated article eligibility and extracted data on study designs, populations enrolled, intervention program characteristics (duration, number of core and maintenance sessions, and outcomes. We used a random effects model to calculate summary estimates for each outcome and associated 95% confidence intervals (CI. To examine sources of heterogeneity, results were stratified according to the presence of maintenance sessions, risk level of participants (prediabetes or other, and intervention delivery personnel (lay or professional. Forty-four studies that enrolled 8,995 participants met eligibility criteria. Participants had an average age of 50.8 years and body mass index (BMI of 34.8 kg/m2, and 25.2% were male. On average, study follow-up was 9.3 mo (median 12.0 with a range of 1.5 to 36 months; programs offered a mean of 12.6 sessions, with mean participant attendance of 11.0 core sessions. Sixty percent of programs offered some form of

  16. Structural origin of set-reset process in a new bulk Si15Te83Ge2 phase-change memory material

    Directory of Open Access Journals (Sweden)

    Srinivasa Rao Gunti

    2011-03-01

    Full Text Available A new phase-change memory material, in bulk, has been prepared by melt-quenching technique, which has a better glass forming ability. This sample is set and resettable relatively easily for several cycles at 2mA SET and RESET input currents, and is likely to be a suitable material for phase-change memory applications. Raman scattering studies have been undertaken during the SET and RESET operations to elucidate the local structural transformations that occur during these operations.

  17. A Secondary Voltage Control Method for an AC/DC Coupled Transmission System Based on Model Predictive Control

    DEFF Research Database (Denmark)

    Xu, Fengda; Guo, Qinglai; Sun, Hongbin;

    2015-01-01

    to keep the voltage of the pilot bus tracking its set point considering the DC system’s transmission schedule change. The approach is inspired by model predictive control (MPC) to compensate for predictable voltage change affected by DC side transmission power flow and the potential capacitor switching...

  18. Game Changing Usage of High-Voltage Power Transmission Systems as Extremely Large Antennas for Space Physical and Geophysical Remote Imaging Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Geomagnetic storms drive geomagnetically induced currents (GIC) in high-voltage power transmission systems worldwide. GIC distribution in the transmission system is...

  19. Phlebotomine sand flies (Diptera: Psychodidae) associated with changing patterns in the transmission of the human cutaneous leishmaniasis in French Guiana.

    Science.gov (United States)

    Fouque, Florence; Gaborit, Pascal; Issaly, Jean; Carinci, Romuald; Gantier, Jean-Charles; Ravel, Christophe; Dedet, Jean-Pierre

    2007-02-01

    Between March 2000 and December 2001 a survey of the sand flies (Diptera: Phlebotominae) of French Guiana was carried out during 14 nights of captures with CDC light-traps and Malaise traps, and resulted in the collection of 2245 individuals of 38 species. The most abundant species were Lutzomyia (Trichophoromyia) ininii Floch & Abonnenc, Lu.(Psychodopygus) squamiventris maripaensis Floch & Abonnenc, and Lu .(Nyssomyia) flaviscutellata Mangabeira. Half of the collected sand flies females were dissected under field conditions and five species were found harboring Leishmania-like parasites. The Leishmania (Kinetoplastidae: Trypanosomatidae) species were identified by molecular typing, and for the first time Lu. (Nys.) flaviscutellata was found harboring Leishmania (Viannia) guyanensis and Lu. (Tri) ininii harboring unknown Leishmania. The first record for French Guiana of Lu. (Psy.) squamiventris maripaensis harboring L. (V.) naiffi, was also reported. The patterns of diversification of the human cutaneous leishmaniasis transmission in French Guiana are discussed.

  20. Phlebotomine sand flies (Diptera: Psychodidae associated with changing patterns in the transmission of the human cutaneous leishmaniasis in French Guiana

    Directory of Open Access Journals (Sweden)

    Florence Fouque

    2007-02-01

    Full Text Available Between March 2000 and December 2001 a survey of the sand flies (Diptera: Phlebotominae of French Guiana was carried out during 14 nights of captures with CDC light-traps and Malaise traps, and resulted in the collection of 2245 individuals of 38 species. The most abundant species were Lutzomyia (Trichophoromyia ininii Floch & Abonnenc, Lu.(Psychodopygus squamiventris maripaensis Floch & Abonnenc, and Lu .(Nyssomyia flaviscutellata Mangabeira. Half of the collected sand flies females were dissected under field conditions and five species were found harboring Leishmania-like parasites. The Leishmania (Kinetoplastidae: Trypanosomatidae species were identified by molecular typing, and for the first time Lu. (Nys. flaviscutellata was found harboring Leishmania (Viannia guyanensis and Lu. (Tri ininii harboring unknown Leishmania. The first record for French Guiana of Lu. (Psy. squamiventris maripaensis harboring L. (V. naiffi, was also reported. The patterns of diversification of the human cutaneous leishmaniasis transmission in French Guiana are discussed.

  1. The effectiveness of multi-component goal setting interventions for changing physical activity behaviour: a systematic review and meta-analysis.

    Science.gov (United States)

    McEwan, Desmond; Harden, Samantha M; Zumbo, Bruno D; Sylvester, Benjamin D; Kaulius, Megan; Ruissen, Geralyn R; Dowd, A Justine; Beauchamp, Mark R

    2016-01-01

    Drawing from goal setting theory (Latham & Locke, 1991; Locke & Latham, 2002; Locke et al., 1981), the purpose of this study was to conduct a systematic review and meta-analysis of multi-component goal setting interventions for changing physical activity (PA) behaviour. A literature search returned 41,038 potential articles. Included studies consisted of controlled experimental trials wherein participants in the intervention conditions set PA goals and their PA behaviour was compared to participants in a control group who did not set goals. A meta-analysis was ultimately carried out across 45 articles (comprising 52 interventions, 126 effect sizes, n = 5912) that met eligibility criteria using a random-effects model. Overall, a medium, positive effect (Cohen's d(SE) = .552(.06), 95% CI = .43-.67, Z = 9.03, p goal setting interventions in relation to PA behaviour was found. Moderator analyses across 20 variables revealed several noteworthy results with regard to features of the study, sample characteristics, PA goal content, and additional goal-related behaviour change techniques. In conclusion, multi-component goal setting interventions represent an effective method of fostering PA across a diverse range of populations and settings. Implications for effective goal setting interventions are discussed.

  2. Improvement of operational stability in SET states of phase-change-type nonvolatile memory devices using Sb-rich phase of Ge-Sb-Te alloys

    Science.gov (United States)

    Yoon, Sung-Min; Lee, Seung-Yun; Jung, Soon-Won; Park, Young-Sam; Yu, Byoung-Gon

    2009-05-01

    For realizing the next-generation phase-change memories (PCM), it is required to reduce the fluctuation of resistance values in SET state. The Sb-rich phase of GeSbTe was proposed to fulfill the complete crystallization process at each SET programming and the PCM devices were fabricated by using the double-layered phase-change materials composed of GeSbTe and GeSbTe. It was found that the SET resistances and their fluctuation were reduced as the increase of volume ratio of the GeSbTe. We can conclude that the compositional modification into the Sb-rich phase can be a good way for improving the SET performances for the PCM applications.

  3. Expert voices for change: bridging the silos-towards healthy and sustainable settings for the 21st century.

    Science.gov (United States)

    Dooris, Mark

    2013-03-01

    The settings approach to health promotion, first advocated in the 1986 Ottawa Charter for Health Promotion, was introduced as an expression of the 'new public health', generating both acclaim and critical discourse. Reflecting an ecological model, a systems perspective and whole system thinking, the approach has been applied in a wide range of geographical and organisational contexts. This paper reports on a qualitative study undertaken through in-depth interviews with key individuals widely acknowledged to have been the architects and pilots of the settings movement. Exploring the development of the settings approach, policy and practice integration, and connectedness 'outwards', 'upwards' and 'beyond health', it concludes that the settings approach has much to offer-but will only realise its potential impact on the wellbeing of people, places and the planet if it builds bridges between silos and reconfigures itself for the globalised 21st century.

  4. The impact of an intervention to introduce malaria rapid diagnostic tests on fever case management in a high transmission setting in Uganda: A mixed-methods cluster-randomized trial (PRIME)

    Science.gov (United States)

    Chandler, Clare I. R.; Webb, Emily L.; Maiteki-Sebuguzi, Catherine; Nayiga, Susan; Nabirye, Christine; DiLiberto, Deborah D.; Ssemmondo, Emmanuel; Dorsey, Grant; Kamya, Moses R.; Staedke, Sarah G.

    2017-01-01

    Background Rapid diagnostic tests for malaria (mRDTs) have been scaled-up widely across Africa. The PRIME study evaluated an intervention aiming to improve fever case management using mRDTs at public health centers in Uganda. Methods A cluster-randomized trial was conducted from 2010–13 in Tororo, a high malaria transmission setting. Twenty public health centers were randomized in a 1:1 ratio to intervention or control. The intervention included training in health center management, fever case management with mRDTs, and patient-centered services; plus provision of mRDTs and artemether-lumefantrine (AL) when stocks ran low. Three rounds of Interviews were conducted with caregivers of children under five years of age as they exited health centers (N = 1400); reference mRDTs were done in children with fever (N = 1336). Health worker perspectives on mRDTs were elicited through semi-structured questionnaires (N = 49) and in-depth interviews (N = 10). The primary outcome was inappropriate treatment of malaria, defined as the proportion of febrile children who were not treated according to guidelines based on the reference mRDT. Findings There was no difference in inappropriate treatment of malaria between the intervention and control arms (24.0% versus 29.7%, adjusted risk ratio 0.81 [95% CI: 0.56, 1.17] p = 0.24). Most children (76.0%) tested positive by reference mRDT, but many were not prescribed AL (22.5% intervention versus 25.9% control, p = 0.53). Inappropriate treatment of children testing negative by reference mRDT with AL was also common (31.3% invention vs 42.4% control, p = 0.29). Health workers appreciated mRDTs but felt that integrating testing into practice was challenging given constraints on time and infrastructure. Conclusions The PRIME intervention did not have the desired impact on inappropriate treatment of malaria for children under five. In this high transmission setting, use of mRDTs did not lead to the reductions in antimalarial prescribing

  5. Description and validation of a new set of object-based temporal geostatistical features for land-use/land-cover change detection

    Science.gov (United States)

    Gil-Yepes, Jose L.; Ruiz, Luis A.; Recio, Jorge A.; Balaguer-Beser, Ángel; Hermosilla, Txomin

    2016-11-01

    A new set of temporal features derived from codispersion and cross-semivariogram geostatistical functions is proposed, described, extracted, and evaluated for object-based land-use/land-cover change detection using high resolution images. Five features were extracted from the codispersion function and another six from the cross-semivariogram. The set of features describes the temporal behaviour of the internal structure of the image objects defined in a cadastral database. The set of extracted features was combined with spectral information and a feature selection study was performed using forward stepwise discriminant analysis, principal component analysis, as well as correlation and feature interpretation analysis. The temporal feature set was validated using high resolution aerial images from an agricultural area located in south-east Spain, in order to solve a tree crop change detection problem. Direct classification using decision tree classifier was used as change detection method. Different classifications were performed comparing various feature group combinations in order to obtain the most suitable features for this study. Results showed that the new sets of cross-semivariogram and codispersion features provided high global accuracy classification results (83.55% and 85.71% respectively), showing high potential for detecting changes related to the internal structure of agricultural tree crop parcels. A significant increase in accuracy value was obtained when combining features from both groups with spectral information (94.59%).

  6. Knowledge Production and Transmission in a Changing Society: Challenges Facing Law Lecturers in a Distance Education Environment in South Africa

    Science.gov (United States)

    Scott, Susan

    2006-01-01

    In this article I highlight the challenges facing a law lecturer in a multicultural society in transformation where the student is being prepared to serve society in different occupational fields as a professional person. I indicate that the law itself cannot effect change. For this we need properly trained lawyers. For an effective transformation…

  7. Combining process-based and correlative models improves predictions of climate change effects on Schistosoma mansoni transmission in eastern Africa

    Directory of Open Access Journals (Sweden)

    Anna-Sofie Stensgaard

    2016-03-01

    Full Text Available Currently, two broad types of approach for predicting the impact of climate change on vector-borne diseases can be distinguished: i empirical-statistical (correlative approaches that use statistical models of relationships between vector and/or pathogen presence and environmental factors; and ii process-based (mechanistic approaches that seek to simulate detailed biological or epidemiological processes that explicitly describe system behavior. Both have advantages and disadvantages, but it is generally acknowledged that both approaches have value in assessing the response of species in general to climate change. Here, we combine a previously developed dynamic, agentbased model of the temperature-sensitive stages of the Schistosoma mansoni and intermediate host snail lifecycles, with a statistical model of snail habitat suitability for eastern Africa. Baseline model output compared to empirical prevalence data suggest that the combined model performs better than a temperature-driven model alone, and highlights the importance of including snail habitat suitability when modeling schistosomiasis risk. There was general agreement among models in predicting changes in risk, with 24-36% of the eastern Africa region predicted to experience an increase in risk of up-to 20% as a result of increasing temperatures over the next 50 years. Vice versa the models predicted a general decrease in risk in 30-37% of the study area. The snail habitat suitability models also suggest that anthropogenically altered habitat play a vital role for the current distribution of the intermediate snail host, and hence we stress the importance of accounting for land use changes in models of future changes in schistosomiasis risk.

  8. A Review of the Current Status of Relevant Zoonotic Pathogens in Wild Swine (Sus scrofa) Populations: Changes Modulating the Risk of Transmission to Humans.

    Science.gov (United States)

    Ruiz-Fons, F

    2017-02-01

    Many wild swine populations in different parts of the World have experienced an unprecedented demographic explosion that may result in increased exposure of humans to wild swine zoonotic pathogens. Interactions between humans and wild swine leading to pathogen transmission could come from different ways, being hunters and game professionals the most exposed to acquiring infections from wild swine. However, increasing human settlements in semi-natural areas, outdoor activities, socio-economic changes and food habits may increase the rate of exposure to wild swine zoonotic pathogens and to potentially emerging pathogens from wild swine. Frequent and increasing contact rate between humans and wild swine points to an increasing chance of zoonotic pathogens arising from wild swine to be transmitted to humans. Whether this frequent contact could lead to new zoonotic pathogens emerging from wild swine to cause human epidemics or emerging disease outbreaks is difficult to predict, and assessment should be based on thorough epidemiologic surveillance. Additionally, several gaps in knowledge on wild swine global population dynamics trends and wild swine-zoonotic pathogen interactions should be addressed to correctly assess the potential role of wild swine in the emergence of diseases in humans. In this work, viruses such as hepatitis E virus, Japanese encephalitis virus, Influenza virus and Nipah virus, and bacteria such as Salmonella spp., Shiga toxin-producing Escherichia coli, Campylobacter spp. and Leptospira spp. have been identified as the most prone to be transmitted from wild swine to humans on the basis of geographic spread in wild swine populations worldwide, pathogen circulation rates in wild swine populations, wild swine population trends in endemic areas, susceptibility of humans to infection, transmissibility from wild swine to humans and existing evidence of wild swine-human transmission events.

  9. Change management and partnership: achieving a solution to provide peritoneal dialysis in a long-term care setting.

    Science.gov (United States)

    Yang, Charlie; Campbell, Jill

    2009-01-01

    Health care organizations must respond quickly to today's volatile and changing environment. This article describes how St. Michael's Hospital (acute care hospital) and the Drs. Paul and John Rekai Centre (long-term care facility) collaborated to use an innovative approach to address pressures of change affecting peritoneal dialysis (PD) care delivery for the elderly. The collaborative applied Galpin's (1996) nine-stage Change Management Model to implement the organizational change. Both organizations generated a shared vision to improve timely access to nursing homes for patients requiring both placement and ongoing peritoneal dialysis. They analyzed their current status and committed resources for the collaboration. Both organizations generated general and detailed recommendations for PD care delivery processes. A pilot was implemented and refinement of the collaboration occurred prior to formal roll out. This application of a change management model to establish organizational partnership may be of interest to those seeking to establish similar collaborations.

  10. Use of Declassified High-Resolution Imagery and Coincident Data Sets for Characterizing the Changing Arctic Ice Cover, and Collaboration with SIZRS

    Science.gov (United States)

    2015-09-30

    Arctic Ocean sea ice cover . OBJECTIVES Literal Image Derived...imagery for understanding of sea ice processes of the Arctic Ocean sea ice cover . RELATED PROJECTS Developing Remote Sensing Capabilities for...Coincident Data Sets for Characterizing the Changing Arctic Ice Cover , and Collaboration with SIZRS” R. Kwok Jet Propulsion Laboratory

  11. Reliability and sensitivity to change of the OMERACT rheumatoid arthritis magnetic resonance imaging score in a multireader, longitudinal setting

    DEFF Research Database (Denmark)

    Haavardsholm, ea; Østergaard, Mikkel; Kvan, NP;

    2005-01-01

    acquired and scored according to the recommendations from the OMERACT MRI group. The intra- and interreader agreement (evaluated by intraclass correlation coefficients [ICCs]) and the sensitivity to change (evaluated by the smallest detectable difference [SDD]) were determined for scores of synovitis.......96 for erosion, and 0.97 for edema). The SDDs were generally low, suggesting a high potential to detect changes. Interreader single-measure ICCs were high for status scores (mean baseline and followup 0.69 and 0.78 for synovitis, 0.83 and 0.73 for erosion, and 0.79 and 0.95 for edema) and for change scores (mean...

  12. Simulation of SET Operation in Phase-Change Random Access Memories with Heater Addition and Ring-Type Contactor for Low-Power Consumption by Finite Element Modeling

    Institute of Scientific and Technical Information of China (English)

    GONG Yue-Feng; SONG Zhi-Tang; LING Yun; LIU Yan; FENG Song-Lin

    2009-01-01

    A three-dimensional finite element model for phase change random access memory (PCRAM) is established for comprehensive electrical and thermal analysis during SET operation. The SET behaviours of the heater addition structure (HS) and the ring-type contact in bottom electrode (RIB) structure are compared with each other. There are two ways to reduce the RESET current, applying a high resistivity interfaciai layer and building a new device structure. The simulation results indicate that the variation of SET current with different power reduction ways is little. This study takes the RESET and SET operation current into consideration, showing that the RIB structure PCRAM cell is suitable for future devices with high heat efficiency and high-density, due to its high heat efficiency in RESET operation.

  13. Using consecutive Rapid Participatory Appraisal studies to assess, facilitate and evaluate health and social change in community settings

    OpenAIRE

    Murray Scott A; Lloyd Simon; Brown Colin S

    2006-01-01

    Abstract Background To investigate how a relatively socio-economically deprived community's needs have changed over time, assess which recommendations from an earlier assessment were implemented and sustained, and consider whether serial Rapid Participatory Appraisal is an effective health research tool that can promote community development and has utility in assessing longitudinal change. Methods Rapid Participatory Appraisal involves communities in identifying and challenging their own hea...

  14. Poster: Observing change in crowded data sets in 3D space - Visualizing gene expression in human tissues

    KAUST Repository

    Rogowski, Marcin

    2013-03-01

    We have been confronted with a real-world problem of visualizing and observing change of gene expression between different human tissues. In this paper, we are presenting a universal representation space based on two-dimensional gel electrophoresis as opposed to force-directed layouts encountered most often in similar problems. We are discussing the methods we devised to make observing change more convenient in a 3D virtual reality environment. © 2013 IEEE.

  15. Perioperative Ruminal pH Changes in Domestic Sheep (Ovis aries) Housed in a Biomedical Research Setting

    OpenAIRE

    Jasmin, Bambi H; Boston, Ray C.; Modesto, Rolf B.; Schaer, Thomas P.

    2011-01-01

    Little information is available on normal ruminal pH values for domestic sheep (Ovis aries) housed in a research setting and fed a complete pelleted ration. Sheep maintained on pelleted diets undergoing surgical procedures often present with postoperative anorexia and rumen atony. To determine the relationship between diet and postoperative rumen acidosis and associated atony, we studied dietary effects on ruminal pH in an ovine surgical model. Sheep undergoing orthopedic surgical procedures ...

  16. Function and its Changes of Agenda Setting in the Network Communication%议程设置在网络传播中的功能及变化

    Institute of Scientific and Technical Information of China (English)

    曹林; 吴铮

    2015-01-01

    "议程设置功能"理论从考察大众传播在人们的环境认知过程中的作用入手,揭示了大众传媒的有力影响.然而,随着新媒体的广泛应用,网络议程设置的重要性逐渐凸显,网络传播互动性强、言论表达自由等特点都使得"议程设置"的模式发生变化.随着传受双方主动性的变迁,出现了公众自我议程设置,并对传统媒体的议程设置产生影响.%Starting from studying mass communication effects in the process of people's environment cognitive, agenda setting function theory reveals the strong influence of mass media. However, with the wide application of new media, the importance of the network agenda setting highlights gradually, the strong interactivity of network spread and freedom of expression etc characteristics make the agenda setting mode changed. With the initiative changes of the two sides of disseminators and recipients, the public self-agenda setting emerges, and has an effect on the agenda setting of traditional media.

  17. Music making for health, well-being and behaviour change in youth justice settings: a systematic review.

    Science.gov (United States)

    Daykin, Norma; de Viggiani, Nick; Pilkington, Paul; Moriarty, Yvonne

    2013-06-01

    Youth justice is an important public health issue. There is growing recognition of the need to adopt effective, evidence-based strategies for working with young offenders. Music interventions may be particularly well suited to addressing risk factors in young people and reducing juvenile crime. This systematic review of international research seeks to contribute to the evidence base on the impact of music making on the health, well-being and behaviour of young offenders and those considered at risk of offending. It examines outcomes of music making identified in quantitative research and discusses theories from qualitative research that might help to understand the impact of music making in youth justice settings.

  18. Using consecutive Rapid Participatory Appraisal studies to assess, facilitate and evaluate health and social change in community settings

    Directory of Open Access Journals (Sweden)

    Murray Scott A

    2006-03-01

    Full Text Available Abstract Background To investigate how a relatively socio-economically deprived community's needs have changed over time, assess which recommendations from an earlier assessment were implemented and sustained, and consider whether serial Rapid Participatory Appraisal is an effective health research tool that can promote community development and has utility in assessing longitudinal change. Methods Rapid Participatory Appraisal involves communities in identifying and challenging their own health-related needs. Information on ten health and social aspects was collated from existing documentation, neighbourhood observations, and interviews with a range of residents and key informants, providing a composite picture of the community's structure, needs and services. Results The perceived needs after 10 years encompassed a wide construct of health, principally the living environment, housing, and lack of finance. Most identified upstream determinants of health rather than specific medical conditions as primary concerns. After the initial Rapid Participatory Appraisal many interviewees took the recommendations forward, working to promote a healthier environment and advocate for local resources. Interventions requiring support from outwith the community were largely not sustained. Conclusion Rapid Participatory Appraisal proved valuable in assessing long-term change. The community's continuing needs were identified, but they could not facilitate and sustain change without the strategic support of key regional and national agencies. Many repeatedly voiced concerns lay outwith local control: local needs assessment must be supported at higher levels to be effective.

  19. Characterizing the regional pattern and temporal change of groundwater levels by analyses of a well log data set

    Institute of Scientific and Technical Information of China (English)

    Mahmuda PARVIN; Naoyuki TADAKUMA; Hisafumi ASAUE; Katsuaki KOIKE

    2011-01-01

    Preservation of the amount and quality of groundwater resources is an important issue around the world.Changes in groundwater levels need to be monitored in efforts to preserve groundwater.This study investigates suitable methods to characterize changes in the groundwater level and determine the factors involved.The area of Kumamoto,a city in central Kyushu,southwest Japan,was selected to demonstrate the usefulness of the methods because this area is one of the richest in Japan in terms of groundwater resources and takes all its water from groundwater.Data of the groundwater level recorded at 69 wells from 1979 to 2007 were used in geostatistical and correlogram analyses.First,strong correlation between the topography and groundwater level was identified.Incorporating this correlation into spatial modeling of the groundwater level,co-kriging was demonstrated to be more accurate than ordinary kriging.The co-kriging results clarified the hydraulic characteristics of the Kumamoto area; the patterns of shallow and deep groundwater levels were agreeable generally,and the general trends of their annual average levels were similar regardless of precipitation.Another important feature was that the correlograms for the precipitation amount and groundwater level had a constant shape and changed smoothly with a change in lag time regardless of the precipitation only in the area of Togawa lava.These characteristics are probably due to the connections between shallow and deep aquifers and the high permeability of Togawa lava.

  20. Goal Setting Is Differentially Related to Change in Fruit, Juice, and Vegetable Consumption among Fourth-Grade Children

    Science.gov (United States)

    Cullen, Karen Weber; Zakeri, Issa; Pryor, Erin W.; Baranowski, Tom; Baranowski, Janice; Watson, Kathy

    2004-01-01

    The impact of goal attainment in a dietary change program to increase fruit, 100% juice, and vegetable consumption was assessed among fourth-grade students. At each session, the students were given goals related to increasing fruit, juice, and vegetable consumption. Baseline consumption and postconsumption were assessed with up to 4 days of…

  1. Changes in action potential duration alter reliance of excitatory synaptic transmission on multiple types of Ca2+ channels in rat hippocampus.

    Science.gov (United States)

    Wheeler, D B; Randall, A; Tsien, R W

    1996-04-01

    It has been established that multiple types of Ca2+ channels participate in triggering neurotransmitter release at central synapses, but there is uncertainty about the nature of their combined actions. We investigated synaptic transmission at CA3-CA1 synapses of rat hippocampal slices and asked whether the dependence on omega-CTx-GVIA-sensitive N-type channels and omega-Aga-IVA-sensitive P/Q-type Ca2+ channels can be altered by physiological mechanisms. The reliance on multiple types of Ca2+ channels was not absolute but depended strongly on the amount of Ca2+ influx through individual channels, which was manipulated by prolonging the presynaptic action potential with the K+ channel blocker 4-aminopyridine (4-AP) and by varying the extracellular Ca2+ concentration ([Ca2+]o). We quantified the influence of spike broadening on Ca2+ influx through various Ca2+ channels by imposing mock action potentials on voltage-clamped cerebellar granule neurons. In field recordings of the EPSP in hippocampal slices, action potential prolongation increased the EPSP slope by 2-fold and decreased its reliance on either N-type or P/Q-type Ca2+ channels. The inhibition of synaptic transmission by N-type channel blockade was virtually eliminated in the presence of 4-AP, but it could be restored by lowering [Ca2+]o. These results rule out a scenario in which a significant fraction of presynaptic terminals rely solely on N-type channels to trigger transmission. The change in sensitivity to the neurotoxins with 4-AP could be explained in terms of a nonlinear relationship between Ca2+ entry and synaptic strength, which rises steeply at low [Ca2+]o, but approaches saturation at high [Ca2+]o. This relationship was evaluated experimentally by varying [CA2+]o in the absence and presence of 4-AP. One consequence of this relationship is that down-modulation of presynaptic Ca2+ channels by various modulators would increase the relative impact of spike broadening greatly.

  2. Assessment of regional climatic changes in the Eastern Himalayan region: a study using multi-satellite remote sensing data sets.

    Science.gov (United States)

    Agrawal, Anubha; Sharma, Anu Rani; Tayal, Shresth

    2014-10-01

    In this study, an attempt has been made to capture the sensitivity of a mountainous region to elevation-dependent warming and the response of a glacier-laden surface to increasing greenhouse gases (GHGs) and aerosol concentration. Some of the changes Sikkim has undergone due to urban sprawl are as follows: an increase of ~0.7 ± 0.46 °C temperature in the past 40 years at an altitude of 5.5 km; a 2.21 km(2)/year rate of loss of glacierised area in the past 33 years; an increase in absorbed longwave radiation (6 ± 2.41 W/m(2)); an increase in heat fluxes (2 ± 0.97 W/m(2)); a decrease in albedo during the last 30 years; an increase in the concentrations of carbon dioxide (4.42%), methane (0.61%), ozone (0.67%) and black carbon column optical depth (7.19%); a decrease in carbon monoxide (2.61%) and an increase in aerosol optical depth (19.16%) during the last decade; a decrease in precipitation, water yield, discharge and groundwater; and an increase in evapotranspiration during 1971-2005. Detection of three climate signals (1976, 1997 and 2005) in the entire analysis is the quantification of the fact that the climate of Sikkim is moving away from its inter-annual variability. An increase in temperature (0.23 °C/decade) at higher altitude (~5.5 km), suppression of precipitation, decreasing water availability and rapid loss of glacierised area are the evidences of the fact that air pollution is playing a significant role in bringing about regional climatic changes in Sikkim. In this study, change detection method has been used for the first time for the estimation of change in a glacierised area of the region.

  3. DATA TRANSMISSION INVESTIGATION

    Science.gov (United States)

    modem will have the capability of 18 bit rates and will be used in the investigation of the short range HF data transmission. System block diagrams of...Field test results of various modems operating over the AN/VRC-12 radio set are presented. Map profiles of each data link are shown and the average...error rates are given for digital data transmission at rates from 300 to 4800 bps. Bit error rates vary depending upon the site and bit rate. The

  4. Quantifying changes in the rates of forest clearing in Indonesia from 1990 to 2005 using remotely sensed data sets

    Science.gov (United States)

    Hansen, Matthew C.; Stehman, Stephen V.; Potapov, Peter V.; Arunarwati, Belinda; Stolle, Fred; Pittman, Kyle

    2009-07-01

    Timely and accurate data on forest change within Indonesia is required to provide government, private and civil society interests with the information needed to improve forest management. The forest clearing rate in Indonesia is among the highest reported by the United Nations Food and Agriculture Organization (FAO), behind only Brazil in terms of forest area lost. While the rate of forest loss reported by FAO was constant from 1990 through 2005 (1.87 Mha yr-1), the political, economic, social and environmental drivers of forest clearing changed at the close of the last century. We employed a consistent methodology and data source to quantify forest clearing from 1990 to 2000 and from 2000 to 2005. Results show a dramatic reduction in clearing from a 1990s average of 1.78 Mha yr-1 to an average of 0.71 Mha yr-1 from 2000 to 2005. However, annual forest cover loss indicator maps reveal a near-monotonic increase in clearing from a low in 2000 to a high in 2005. Results illustrate a dramatic downturn in forest clearing at the turn of the century followed by a steady resurgence thereafter to levels estimated to exceed 1 Mha yr-1 by 2005. The lowlands of Sumatra and Kalimantan were the site of more than 70% of total forest clearing within Indonesia for both epochs; over 40% of the lowland forests of these island groups were cleared from 1990 to 2005. The method employed enables the derivation of internally consistent, national-scale changes in the rates of forest clearing, results that can inform carbon accounting programs such as the Reducing Emissions from Deforestation and Forest Degradation in Developing Countries (REDD) initiative.

  5. System Re-set: High LET Radiation or Transient Musculoskeletal Disuse Cause Lasting Changes in Oxidative Defense Pathways Within Bone

    Science.gov (United States)

    Kumar, Akhilesh; Chatterjee, A.; Alwood, Joshua S.; Dvorochkin, Natalya; Almeida, Eduardo A. C.

    2011-01-01

    Six months post-IR, there were no notable changes in skeletal expression of 84 principal genes in the p53 signaling pathway due to low dose IR (0.5Gy), HU, or both. In contrast, numerous genes relevant to oxidative stress were regulated by the treatments, typically in a direction indicative of increased oxidative stress and impaired defense. IR and HU independently reduced (between 0.46 to 0.88 fold) expression levels of Noxa1, Gpx3, Prdx2, Prdx3, and Zmynd17. Surprisingly, transient HU alone (sham-irradiated) decreased expression of several redox-related genes (Gpx1,Gstk1, Prdx1, Txnrd2), which were not affected significantly by IR alone. Irradiation increased (1.13 fold) expression of a gene responsible for production of superoxides by neutrophils (NCF2). Of interest, only combined treatment with HU and IR led to increased expression levels of Ercc2, (1.19 fold), a DNA excision repair enzyme. Differences in gene expression levels may reflect a change in gene expression on a per cell basis, a shift in the repertoire of specific cell types within the tissue, or both. Serum nitrite/nitrate levels were elevated to comparable levels (1.6-fold) due to IR, HU or both, indicative of elevated systemic nitrosyl stress. CONCLUSIONS The magnitude of changes in skeletal expression of oxidative stress-related genes six months after irradiation and/or transient unloading tended to be relatively modest (0.46-1.15 fold), whereas the p53 pathway was not affected. The finding that many different oxidative stress-related genes differed from controls at this late time point implicates a generalized impairment of oxidative defense within skeletal tissue, which coincides with both profound radiation damage to osteoprogenitors/stem cells in bone marrow and impaired remodeling of mineralized tissue.

  6. Method and Device for Speed Change by the Epicyclic Gear Train with Stepped-Planet Gear Set

    Directory of Open Access Journals (Sweden)

    Malashchenko Volodymyr

    2016-08-01

    Full Text Available The article describes new method and device for continuously variable speed change management via compound epicyclic gearing with composite planet gears and closed circuit hydrosystem, when the speed control element is either outer ring gear (annulus or the carrier or sun gear. In each case, the control element connected to closed circuit hydrosystem and can be in motion or immovable depending on the bandwidth of hydrosystem’s regulating throttle. We had held theoretical research and received graphic dependences between velocities of driving, control and driven elements by means of computer programing.

  7. Sensitivity analysis of torsional vibration behavior of the shafting of a turbo generator set to changes of its mechanical parameters

    Institute of Scientific and Technical Information of China (English)

    XIE Danmei; LIU Zhanhui; ZHANG Hengliang; YANG Changzhu; DONG Chuan

    2007-01-01

    Aiming at a 300 MW turbo-generator model,the sensitivity of natural torsional frequencies and modes of torsional vibration (TV) to the rotational inertia and stiffness of the turbo-generator were analyzed.Calculation results show that the variation of the rotational inertia or stiffness either of the rotor system as a whole (namely shafting) or only locally may both remarkably influence the TV characteristics of the rotor.The influence of localized variation is still notable although it is not as great as that of the rotor as a whole.The segments on the shafting,which contribute more to a certain mode of vibration,have a greater influence on the pertaining order of TV.Compared with the modal shape,a larger slope can be observed at these sections of the rotor for the particular mode.Thus,frequencies can be modulated by modifying the local construction of the rotor to make the natural TV frequency of a certain order avoid some specific value,herewith arriving at the objective of tuning.Therefore,it is very important,in the course of modeling for the purpose of studying the TV of the shafting of a turbo-set,to accurately determine the structural parameters of parts that have a relatively sensitive effect on the TV behavior.

  8. Perioperative ruminal pH changes in domestic sheep (Ovis aries) housed in a biomedical research setting.

    Science.gov (United States)

    Jasmin, Bambi H; Boston, Ray C; Modesto, Rolf B; Schaer, Thomas P

    2011-01-01

    Little information is available on normal ruminal pH values for domestic sheep (Ovis aries) housed in a research setting and fed a complete pelleted ration. Sheep maintained on pelleted diets undergoing surgical procedures often present with postoperative anorexia and rumen atony. To determine the relationship between diet and postoperative rumen acidosis and associated atony, we studied dietary effects on ruminal pH in an ovine surgical model. Sheep undergoing orthopedic surgical procedures were randomized into 2 diet groups. Group 1 (n = 6) was fed complete pelleted diet during the pre- and postoperative period, and group 2 (n = 6) was fed timothy grass hay exclusively throughout the study. Measures included ruminal pH, ruminal motility, and rate of feed refusal, which was monitored throughout the pre- and postoperative periods. The 2 groups did not differ significantly before surgery, and the ruminal parameters remained largely within normal limits. However, a downward trend in the strength and frequency of rumen contractions was observed in pellet-fed sheep. After surgery, the pellet-fed group showed clinical signs consistent with ruminal acidosis, supported by decreased ruminal motility, anorexia, putrid-smelling ruminal material, and death of ruminal protozoa. Intervention by transfaunation in clinically affected sheep resulted in resolution of signs. Our findings suggest that sheep fed grass hay appear to have a more stable ruminal pH, are less likely to experience anorexia and rumen atony, and thereby exhibit fewer postoperative gastrointestinal complications than do sheep on a pellet diet.

  9. Moving into protected areas? Setting conservation priorities for Romanian reptiles and amphibians at risk from climate change.

    Science.gov (United States)

    Popescu, Viorel D; Rozylowicz, Laurenţiu; Cogălniceanu, Dan; Niculae, Iulian Mihăiţă; Cucu, Adina Livia

    2013-01-01

    Rapid climate change represents one of the top threats to biodiversity, causing declines and extinctions of many species. Range shifts are a key response, but in many cases are incompatible with the current extent of protected areas. In this study we used ensemble species distribution models to identify range changes for 21 reptile and 16 amphibian species in Romania for the 2020s and 2050s time horizons under three emission scenarios (A1B = integrated world, rapid economic growth, A2A = divided world, rapid economic growth [realistic scenario], B2A = regional development, environmentally-friendly scenario) and no- and limited-dispersal assumptions. We then used irreplaceability analysis to test the efficacy of the Natura 2000 network to meet conservation targets. Under all scenarios and time horizons, 90% of the species suffered range contractions (greatest loses under scenarios B2A for 2020s, and A1B for 2050s), and four reptile species expanded their ranges. Two reptile and two amphibian species are predicted to completely lose climate space by 2050s. Currently, 35 species do not meet conservation targets (>40% representation in protected areas), but the target is predicted to be met for 4 - 14 species under future climate conditions, with higher representation under the limited-dispersal scenario. The Alpine and Steppic-Black Sea biogeographic regions have the highest irreplaceability value, and act as climate refugia for many reptiles and amphibians. The Natura 2000 network performs better for achieving herpetofauna conservation goals in the future, owing to the interaction between drastic range contractions, and range shifts towards existing protected areas. Thus, conservation actions for herpetofauna in Romania need to focus on: (1) building institutional capacity of protected areas in the Alpine and Steppic-Black Sea biogeographic regions, and (2) facilitating natural range shifts by improving the conservation status of herpetofauna outside protected areas

  10. Moving into protected areas? Setting conservation priorities for Romanian reptiles and amphibians at risk from climate change.

    Directory of Open Access Journals (Sweden)

    Viorel D Popescu

    Full Text Available Rapid climate change represents one of the top threats to biodiversity, causing declines and extinctions of many species. Range shifts are a key response, but in many cases are incompatible with the current extent of protected areas. In this study we used ensemble species distribution models to identify range changes for 21 reptile and 16 amphibian species in Romania for the 2020s and 2050s time horizons under three emission scenarios (A1B = integrated world, rapid economic growth, A2A = divided world, rapid economic growth [realistic scenario], B2A = regional development, environmentally-friendly scenario and no- and limited-dispersal assumptions. We then used irreplaceability analysis to test the efficacy of the Natura 2000 network to meet conservation targets. Under all scenarios and time horizons, 90% of the species suffered range contractions (greatest loses under scenarios B2A for 2020s, and A1B for 2050s, and four reptile species expanded their ranges. Two reptile and two amphibian species are predicted to completely lose climate space by 2050s. Currently, 35 species do not meet conservation targets (>40% representation in protected areas, but the target is predicted to be met for 4 - 14 species under future climate conditions, with higher representation under the limited-dispersal scenario. The Alpine and Steppic-Black Sea biogeographic regions have the highest irreplaceability value, and act as climate refugia for many reptiles and amphibians. The Natura 2000 network performs better for achieving herpetofauna conservation goals in the future, owing to the interaction between drastic range contractions, and range shifts towards existing protected areas. Thus, conservation actions for herpetofauna in Romania need to focus on: (1 building institutional capacity of protected areas in the Alpine and Steppic-Black Sea biogeographic regions, and (2 facilitating natural range shifts by improving the conservation status of herpetofauna outside

  11. Lessons learned from curriculum changes and setting curriculum objectives at the University of Pennsylvania's Earth and Environmental Science Department

    Science.gov (United States)

    Dmochowski, J. E.

    2009-12-01

    Recent restructuring of the University of Pennsylvania’s curriculum, including a revised multi-disciplinary Environmental Studies major and a proposed Environmental Science major has led to several changes, including a mandatory junior research seminar. Feedback from students indicates that a more structured curriculum has helped guide them through the multi-disciplinary Environmental Studies major. The addition of mandatory courses in Statistics, Geographical and Environmental Modeling, as well as Economics and Policy has ensured that students have important skills needed to succeed after graduation. We have compiled a curriculum objective matrix to clarify both the broad and focused objectives of our curriculum and how each course helps to fulfill these objectives. An important aspect of both majors is the Senior Thesis. The junior research seminar was recently revised to help students prepare for their thesis research. Topic selection, library research, data presentation, basic research methods, advisor identification, and funding options are discussed. Throughout the course, faculty from within the department lecture about their research and highlight opportunities for undergraduates. In one assignment, students are given a few types of datasets and asked to present the data and error analysis in various formats using different software (SPSS and Excel). The final paper was a research proposal outlining the student’s Senior Thesis. Based on both the university and instructor written course evaluations, students felt they benefited most from writing their senior thesis proposal; doing assignments on data analysis, library research and critical analysis; and the faculty research lectures. The lessons learned in restructuring this flexible major and providing a research seminar in the junior year may benefit other departments considering such changes.

  12. HIV Transmission

    Science.gov (United States)

    ... Abroad Treatment Basic Statistics Get Tested Find an HIV testing site near you. Enter ZIP code or city Follow HIV/AIDS CDC HIV CDC HIV/AIDS See RSS | ... on HIV Syndicated Content Website Feedback HIV/AIDS HIV Transmission Language: English Transmisión del VIH Recommend on ...

  13. Transmission design in a multimode HFC network

    Science.gov (United States)

    Cambron, G. Keith

    1996-11-01

    Contemporary hybrid fiber coaxial (HFC) networks are capable of supporting a wide range of services including traditional analog video, telephony, digital video, and data services. Each service has unique performance or service requirements. This contribution examines transmission design for one such network. Pacific Bell's advanced communications network (ACN). The design methodology begins with a set of end to end service quality objectives. Network impairments, such as noise, distortion and delay, are allocated across the network elements using a set of standard network models. These models are a representative set of the actual field designs and bound the network operating parameters. Network components, headend equipment, and customer premises equipment are specified analytically or characterized empirically in relationship to the chosen impairment set. The component parameters are then included in analytical models to estimate overall network performance. In addition to the forward path transmission considerations examined by traditional coaxial network designers, other dimensions including power consumption, traffic demand, and message latency are taken into account. Analytical models are used to estimate the effects of multiple modulation schemes within the unified network. The variability introduced by on demand services such as telephony and interactive digital services changes the base computational domain from deterministic models to stochastic ones. These models are then used to set operating parameters at measurable points throughout the network for proof of performance prior to turn up, and for ongoing performance monitoring. For closure, empirical results are compared with model projections as a way of verifying and improving the predictive models.

  14. Price transmission in the agri-food value chain - from a farmer perspective

    DEFF Research Database (Denmark)

    Hansen, Henning Otte

    2015-01-01

    Price transmission in the agri-food value chain - when changes in one price cause another price downstream to change - is an important issue for farmers, markets and the economy as an efficient market price setting is crucial for all market players. However, there are numerous examples of price t...

  15. Transmission positron microscopes

    Energy Technology Data Exchange (ETDEWEB)

    Doyama, Masao [Teikyo University of Science and Technology, Uenohara, Yamanashi 409-0193 (Japan)]. E-mail: doyama@ntu.ac.jp; Kogure, Yoshiaki [Teikyo University of Science and Technology, Uenohara, Yamanashi 409-0193 (Japan); Inoue, Miyoshi [Teikyo University of Science and Technology, Uenohara, Yamanashi 409-0193 (Japan); Kurihara, Toshikazu [Institute of Materials Structure Science (IMSS), High Energy Accelerator, Research Organization (KEK), Ohno 1-1, Tsukuba, Ibaraki 305-0801 (Japan); Yoshiie, Toshimasa [Reactor Research Institute, Kyoto University, Noda, Kumatori, Osaka 590-0451 (Japan); Oshima, Ryuichiro [Research Institute for Advanced Science and Technology, Osaka Prefecture University (Japan); Matsuya, Miyuki [Electron Optics Laboratory (JEOL) Ltd., Musashino 3-1-2, Akishima 196-0021 (Japan)

    2006-02-28

    Immediate and near-future plans for transmission positron microscopes being built at KEK, Tsukuba, Japan, are described. The characteristic feature of this project is remolding a commercial electron microscope to a positron microscope. A point source of electrons kept at a negative high voltage is changed to a point source of positrons kept at a high positive voltage. Positional resolution of transmission microscopes should be theoretically the same as electron microscopes. Positron microscopes utilizing trapping of positrons have always positional ambiguity due to the diffusion of positrons.

  16. Transcending Transmission

    DEFF Research Database (Denmark)

    Schoeneborn, Dennis; Trittin, Hannah

    2013-01-01

    Purpose – Extant research on corporate social responsibility (CSR) communication primarily relies on a transmission model of communication that treats organizations and communication as distinct phenomena. This approach has been criticized for neglecting the formative role of communication...... in the emergence of organizations. This paper seeks to propose to reconceptualize CSR communication by drawing on the “communication constitutes organizations” (CCO) perspective. Design/methodology/approach – This is a conceptual paper that explores the implications of switching from an instrumental...

  17. Impacts of Demand-Side Resources on Electric Transmission Planning

    Energy Technology Data Exchange (ETDEWEB)

    Hadley, Stanton W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sanstad, Alan H. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-01-01

    Will demand resources such as energy efficiency (EE), demand response (DR), and distributed generation (DG) have an impact on electricity transmission requirements? Five drivers for transmission expansion are discussed: interconnection, reliability, economics, replacement, and policy. With that background, we review the results of a set of transmission studies that were conducted between 2010 and 2013 by electricity regulators, industry representatives, and other stakeholders in the three physical interconnections within the United States. These broad-based studies were funded by the US Department of Energy and included scenarios of reduced load growth due to EE, DR, and DG. While the studies were independent and used different modeling tools and interconnect-specific assumptions, all provided valuable results and insights. However, some caveats exist. Demand resources were evaluated in conjunction with other factors, and limitations on transmission additions between scenarios made understanding the role of demand resources difficult. One study, the western study, included analyses over both 10- and 20-year planning horizons; the 10-year analysis did not show near-term reductions in transmission, but the 20-year indicated fewer transmission additions, yielding a 36percent capital cost reduction. In the eastern study the reductions in demand largely led to reductions in local generation capacity and an increased opportunity for low-cost and renewable generation to export to other regions. The Texas study evaluated generation changes due to demand, and is in the process of examining demand resource impacts on transmission.

  18. Three-year change in the wellbeing of orphaned and separated children in institutional and family-based care settings in five low- and middle-income countries.

    Directory of Open Access Journals (Sweden)

    Kathryn Whetten

    Full Text Available BACKGROUND: With more than 2 million children living in group homes, or "institutions", worldwide, the extent to which institution-based caregiving negatively affects development and wellbeing is a central question for international policymakers. METHODS: A two-stage random sampling methodology identified community representative samples of 1,357 institution-dwelling orphaned and separated children (OSC and 1,480 family-dwelling OSC aged 6-12 from 5 low and middle income countries. Data were collected from children and their primary caregivers. Survey-analytic techniques and linear mixed effects models describe child wellbeing collected at baseline and at 36 months, including physical and emotional health, growth, cognitive development and memory, and the variation in outcomes between children, care settings, and study sites. FINDINGS: At 36-month follow-up, institution-dwelling OSC had statistically significantly higher height-for-age Z-scores and better caregiver-reported physical health; family-dwelling OSC had fewer caregiver-reported emotional difficulties. There were no statistically significant differences between the two groups on other measures. At both baseline and follow-up, the magnitude of the differences between the institution- and family-dwelling groups was small. Relatively little variation in outcomes was attributable to differences between sites (11-27% of total variation or care settings within sites (8-14%, with most variation attributable to differences between children within settings (60-75%. The percent of variation in outcomes attributable to the care setting type, institution- versus family-based care, ranged from 0-4% at baseline, 0-3% at 36-month follow-up, and 0-4% for changes between baseline and 36 months. INTERPRETATION: These findings contradict the hypothesis that group home placement universally adversely affects child wellbeing. Without substantial improvements in and support for family settings, the removal

  19. Mechanisms, Transmissions and Applications

    CERN Document Server

    Corves, Burkhard

    2012-01-01

    The first Workshop on Mechanisms, Transmissions and Applications -- MeTrApp-2011 was organized by the Mechatronics Department at the Mechanical Engineering Faculty, “Politehnica” University of Timisoara, Romania, under the patronage of the IFToMM Technical Committees Linkages and Mechanical Controls and Micromachines. The workshop brought together researchers and students who work in disciplines associated with mechanisms science and offered a great opportunity for scientists from all over the world to present their achievements, exchange innovative ideas and create solid international links, setting the trend for future developments in this important and creative field. The topics treated in this volume are mechanisms and machine design, mechanical transmissions, mechatronic and biomechanic applications, computational and experimental methods, history of mechanism and machine science and teaching methods.

  20. Hematological changes in women and infants exposed to an AZT-containing regimen for prevention of mother-to-child-transmission of HIV in Tanzania.

    Directory of Open Access Journals (Sweden)

    Judith Ziske

    Full Text Available INTRODUCTION: Tanzanian guidelines for prevention of mother-to-child-transmission of HIV (PMTCT recommend an antiretroviral combination regimen involving zidovudine (AZT during pregnancy, single-dosed nevirapine at labor onset, AZT plus Lamivudine (3TC during delivery, and AZT/3TC for 1-4 weeks postpartum. As drug toxicities are a relevant concern, we assessed hematological alterations in AZT-exposed women and their infants. METHODS AND MATERIALS: A cohort of HIV-positive women, either with AZT intake (n = 82, group 1 or without AZT intake (n = 62, group 2 for PMTCT during pregnancy, was established at Kyela District Hospital, Tanzania. The cohort also included the infants of group 1 with an in-utero AZT exposure ≥4 weeks, receiving AZT for 1 week postpartum (n = 41, and infants of group 2 without in-utero AZT exposure, receiving a prolonged 4-week AZT tail (n = 58. Complete blood counts were evaluated during pregnancy, birth, weeks 4-6 and 12. RESULTS: For women of group 1 with antenatal AZT intake, we found a statistically significant decrease in hemoglobin level, red blood cells, white blood cells, granulocytes, as well as an increase in red cell distribution width and platelet count. At delivery, the median red blood cell count was significantly lower and the median platelet count was significantly higher in women of group 1 compared to group 2. At birth, infants from group 1 showed a lower median hemoglobin level and granulocyte count and a higher frequency of anemia and granulocytopenia. At 4-6 weeks postpartum, the mean neutrophil granulocyte count was significantly lower and neutropenia was significantly more frequent in infants of group 2. CONCLUSIONS: AZT exposure during pregnancy as well as after birth resulted in significant hematological alterations for women and their newborns, although these changes were mostly mild and transient in nature. Research involving larger cohorts is needed to further analyze the impact

  1. From TV Sets to Network The Change of the TV Media%论新时期电视剧传播媒介的变革

    Institute of Scientific and Technical Information of China (English)

    朱超颖

    2011-01-01

    互联网的出现不仅对传统媒体造成了很大冲击,而且改变着电视剧创作趋势、创作者的理念,对电视剧的传播产生了极大影响。%The emergence of the Internet has a great impact on Traditional media. The Most Important factor is the TV Media is congenital limited to the TV set. Combing With the Characteristic of Net Media and analyzing the causes of environment , audience, space, communication unit, communication channel and information, we can find the convenience have great influence upon the behaviors and preferences of TV audiences. Creation tendency and creator's concept changed with audience'sperception and Internet Drama also has great influence on it.

  2. Measuring Post-Partum Haemorrhage in Low-Resource Settings: The Diagnostic Validity of Weighed Blood Loss versus Quantitative Changes in Hemoglobin.

    Directory of Open Access Journals (Sweden)

    Esther Cathyln Atukunda

    Full Text Available Accurate estimation of blood loss is central to prompt diagnosis and management of post-partum hemorrhage (PPH, which remains a leading cause of maternal mortality in low-resource countries. In such settings, blood loss is often estimated visually and subjectively by attending health workers, due to inconsistent availability of laboratory infrastructure. We evaluated the diagnostic accuracy of weighed blood loss (WBL versus changes in peri-partum hemoglobin to detect PPH.Data from this analysis were collected as part of a randomized controlled trial comparing oxytocin with misoprostol for PPH (NCT01866241. Blood samples for complete blood count were drawn on admission and again prior to hospital discharge or before blood transfusion. During delivery, women were placed on drapes and had pre-weighed sanitary towels placed around their perineum. Blood was then drained into a calibrated container and the sanitary towels were added to estimate WBL, where each gram of blood was estimated as a milliliter. Sensitivity, specificity, negative and positive predictive values (PPVs were calculated at various blood volume loss and time combinations, and we fit receiver-operator curves using blood loss at 1, 2, and 24 hours compared to a reference standard of haemoglobin decrease of >10%.A total of 1,140 women were enrolled in the study, of whom 258 (22.6% developed PPH, defined as a haemoglobin drop >10%, and 262 (23.0% had WBL ≥500mL. WBL generally had a poor sensitivity for detection of PPH (85% in high prevalence settings when WBL exceeds 750mL.WBL has poor sensitivity but high specificity compared to laboratory-based methods of PPH diagnosis. These characteristics correspond to a high PPV in areas with high PPH prevalence. Although WBL is not useful for excluding PPH, this low-cost, simple and reproducible method is promising as a reasonable method to identify significant PPH in such settings where quantifiable red cell indices are unavailable.

  3. Mode of delivery in HIV-infected pregnant women and prevention of mother-to-child transmission: changing practices in Western Europe

    DEFF Research Database (Denmark)

    NN, NN; Boer, K; England, K

    2010-01-01

    The aim of the study was to examine temporal and geographical patterns of mode of delivery in the European Collaborative Study (ECS), identify factors associated with elective caesarean section (CS) delivery in the highly active antiretroviral therapy (HAART) era and explore associations between ...... mode of delivery and mother-to-child transmission (MTCT)....

  4. Quantum Contact Transmission

    Institute of Scientific and Technical Information of China (English)

    崔迪

    2015-01-01

    Abstract:Quantum transmission is based on quantum entanglement, which is a kind of the phenomenon of quantum mechanics. Quantum object refers to two or more between the localized, the classic strong correlation. When two object quantum entanglement in the quantum state is not independent, but related, and the correlation distance, a pair of electronic of entanglement state, no matter how far apart, they spin direction will remain an up and a down. If one of the electronic spin direction is changed, another of the electron spin direction wil follow to change immediately.

  5. High intensity interval training in a real world setting: a randomized controlled feasibility study in overweight inactive adults, measuring change in maximal oxygen uptake.

    Directory of Open Access Journals (Sweden)

    Helen Lunt

    Full Text Available BACKGROUND: In research clinic settings, overweight adults undertaking HIIT (high intensity interval training improve their fitness as effectively as those undertaking conventional walking programs but can do so within a shorter time spent exercising. We undertook a randomized controlled feasibility (pilot study aimed at extending HIIT into a real world setting by recruiting overweight/obese, inactive adults into a group based activity program, held in a community park. METHODS: Participants were allocated into one of three groups. The two interventions, aerobic interval training and maximal volitional interval training, were compared with an active control group undertaking walking based exercise. Supervised group sessions (36 per intervention were held outdoors. Cardiorespiratory fitness was measured using VO2max (maximal oxygen uptake, results expressed in ml/min/kg, before and after the 12 week interventions. RESULTS: On ITT (intention to treat analyses, baseline (N = 49 and exit (N = 39 [Formula: see text]O2 was 25.3±4.5 and 25.3±3.9, respectively. Participant allocation and baseline/exit VO2max by group was as follows: Aerobic interval training N =  16, 24.2±4.8/25.6±4.8; maximal volitional interval training N = 16, 25.0±2.8/25.2±3.4; walking N = 17, 26.5±5.3/25.2±3.6. The post intervention change in VO2max was +1.01 in the aerobic interval training, -0.06 in the maximal volitional interval training and -1.03 in the walking subgroups. The aerobic interval training subgroup increased VO2max compared to walking (p = 0.03. The actual (observed, rather than prescribed time spent exercising (minutes per week, ITT analysis was 74 for aerobic interval training, 45 for maximal volitional interval training and 116 for walking (p =  0.001. On descriptive analysis, the walking subgroup had the fewest adverse events. CONCLUSIONS: In contrast to earlier studies, the improvement in cardiorespiratory fitness in a

  6. The evolution of transmission mode

    Science.gov (United States)

    Forbes, Mark R.; Hauffe, Heidi C.; Kallio, Eva R.; Okamura, Beth; Sait, Steven M.

    2017-01-01

    This article reviews research on the evolutionary mechanisms leading to different transmission modes. Such modes are often under genetic control of the host or the pathogen, and often in conflict with each other via trade-offs. Transmission modes may vary among pathogen strains and among host populations. Evolutionary changes in transmission mode have been inferred through experimental and phylogenetic studies, including changes in transmission associated with host shifts and with evolution of the unusually complex life cycles of many parasites. Understanding the forces that determine the evolution of particular transmission modes presents a fascinating medley of problems for which there is a lack of good data and often a lack of conceptual understanding or appropriate methodologies. Our best information comes from studies that have been focused on the vertical versus horizontal transmission dichotomy. With other kinds of transitions, theoretical approaches combining epidemiology and population genetics are providing guidelines for determining when and how rapidly new transmission modes may evolve, but these are still in need of empirical investigation and application to particular cases. Obtaining such knowledge is a matter of urgency in relation to extant disease threats. This article is part of the themed issue ‘Opening the black box: re-examining the ecology and evolution of parasite transmission’. PMID:28289251

  7. ECOLOGICAL CHANGE AS A FACTOR IN RENEWED MALARIA TRANSMISSION IN AN ERADICATED AREA. A LOCALIZED OUTBREAK OF A. AQUASALIS-TRANSMITTED MALARIA ON THE DEMERARA RIVER ESTUARY, BRITISH GUIANA, IN THE FIFTEENTH YEAR OF A. DARLINGI AND MALARIA ERADICATION.

    Science.gov (United States)

    GIGLIOLI, G

    1963-01-01

    In British Guiana, the successful eradication of Anopheles darlingi and malaria from the coastal areas has caused a very rapid increase in the population and has favoured a considerable social and economic improvement and expansion of both agriculture and industry. Housing and industrial developments and the constantly expanding rice cultivation have taken over most of the accessible pasture-lands, displacing the livestock which previously abounded around villages and settlements. Mechanization on the roads and in the fields increases daily, and the horse, the mule, the donkey and the ploughing oxen are gradually becoming obsolete.In some areas these changes have already caused such an upset in the balance between the human and the livestock population that A. aquasalis, a very abundant species all along the coast, but until recently entirely "fixed" by the livestock population, is now shifting its attention from livestock to man. On the Demerara river estuary, an area where malaria transmission was interrupted sixteen years ago and where eradication has been continually maintained, this mosquito has been responsible for a sharp, but localized, outbreak of P. vivax malaria. An entirely new epidemiological problem thus presents itself.Environmental changes, introduced and fostered by successful malaria eradication, may thus cause an anopheline species, potentially capable of malaria transmission, but originally inactive and harmless as a vector, to alter its feeding habits and thereby renew transmission. The immediate and long-term significance of some secondary and potential vectors may therefore require renewed evaluation in the planning of malaria eradication campaigns.

  8. Digital data set of water-level changes in the High Plains aquifer in parts of Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming, 1980 to 1996

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digital water-level-change contours for the High Plains aquifer in the Central United States, 1980 to 1996. The High Plains aquifer extends...

  9. Digital data set of water-level changes in the High Plains aquifer in parts of Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming, 1980 to 1994

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digital water-level-change contour for the High Plains aquifer in the Central United States, 1980 to 1994. The High Plains aquifer extends...

  10. Digital data set of water-level changes in the High Plains aquifer in parts of Colorado, Kansas, Nebraska, New Mexico, Oklahoma, South Dakota, Texas, and Wyoming, 1980 to 1995

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set consists of digital water-level-change contours for the High Plains aquifer in the central United States, 1980 to 1995. The High Plains aquifer extends...

  11. Diagnostic stability of autism spectrum disorder in toddlers prospectively identified in a community-based setting: Behavioural characteristics and predictors of change over time.

    Science.gov (United States)

    Barbaro, Josephine; Dissanayake, Cheryl

    2016-07-28

    Autism spectrum disorder diagnoses in toddlers have been established as accurate and stable across time in high-risk siblings and clinic-referred samples. Few studies have investigated diagnostic stability in children prospective identified in community-based settings. Furthermore, there is a dearth of evidence on the individual behaviours that predict diagnostic change over time. The stability and change of autism spectrum disorder diagnoses were investigated from 24 to 48 months in 77 children drawn from the Social Attention and Communication Study. Diagnostic stability was high, with 88.3% overall stability and 85.5% autism spectrum disorder stability. The behavioural markers at 24 months that contributed to diagnostic shift off the autism spectrum by 48 months included better eye contact, more directed vocalisations, the integration of gaze and directed vocalisations/gestures and higher non-verbal developmental quotient. These four variables correctly predicted 88.7% of children into the autism spectrum disorder-stable and autism spectrum disorder-crossover groups overall, with excellent prediction for the stable group (96.2%) and modest prediction for the crossover group (44.4%). Furthermore, non-verbal developmental quotient at 24 months accounted for the significant improvement across time in 'Social Affect' scores on the Autism Diagnostic Observation Schedule for both groups and was the only unique predictor of diagnostic crossover. These findings contribute to the body of evidence on the feasibility of diagnoses at earlier ages to facilitate children's access to interventions to promote positive developmental outcomes.

  12. Tremendous change of the earth surface system and tectonic setting of salt-lake formation in Yuncheng Basin since 7.1 Ma

    Institute of Scientific and Technical Information of China (English)

    王强; 李彩光; 田国强; 张文治; 刘椿; 宁联元; 岳军; 程自刚; 何翠英

    2002-01-01

    The Yuncheng salt lake has formed under the setting of stepped subsidence of fault-blocks from the north to the south in Yuncheng Basin. In the phase of red clay accumulation during 7.1-3.6 Ma, the size of palaeo-lake was larger than the present salt lake, and palaeo-monsoon had formed. At 3.6 Ma, the northern basement in the basin raised abruptly due to the radiative effect of Qinghai-Tibet Plateau uplifting, and palaeo-lake was contracting southwards. At ca. 2.6 Ma ancient river flowed into the northern part of the basin. During ca. 2.0-1.9 Ma aerolian effect strengthened and loess started to accumulate on the most part of the basin. Since ca. 1.8-1.0 Ma the subsidence of the lake fault-block has been speeding up abruptly. As under the natural hydrogradient the salt lake received enough groundwater supply, and the rate of loess accumulation in the lake area was lower than that of subsidence of the lake fault-block, the lake could be preserved and becomes the only modern lake on Chinese Loess Plateau. Four large strengthening change records of the monsoon were found in the lake sequence of 5.8-1.9 Ma B.P.

  13. How the Second Delta Committee Set the Agenda for Climate Adaptation Policy: A Dutch Case Study on Framing Strategies for Policy Change

    Directory of Open Access Journals (Sweden)

    Simon H. Verduijn

    2012-06-01

    Full Text Available In 2008, the Second State Delta Committee, commissioned by the Dutch Secretary of Public Works and Water Management, provided suggestions on how to defend the Netherlands against the expected impacts of climate change, such as sea level rise, longer periods of drought, more intense periods of rainfall and additional land subsidence over the coming two hundred years (Veerman, 2008. In this paper we show that even though no crisis actually occurred, the Second Delta Committee succeeded in three areas. First, the committee managed to create awareness and set the agenda for climate adaptation policy and the issue of safety in Dutch water management. Second, the committee succeeded to a large extent in getting the media, the public and politics to accept its frame and framing of the problems, causes, moral judgments and suggested remedies. Third, the committee has to a certain degree already succeeded in having its recommendations translated into policy programmes. It will be argued that framing strategies were key to the committee’s success and that the committee used various framing strategies to convince the Cabinet, citizens and others of the urgency and necessity of implementing adaptation measures. The most important framing strategies identified were adherence to the climate adaptation narrative, using the story of our delta identity, creating a sense of urgency and collectiveness, and creating a crisis narrative.

  14. Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity.

    Science.gov (United States)

    Carobbio, Stefania; Hagen, Rachel M; Lelliott, Christopher J; Slawik, Marc; Medina-Gomez, Gema; Tan, Chong-Yew; Sicard, Audrey; Atherton, Helen J; Barbarroja, Nuria; Bjursell, Mikael; Bohlooly-Y, Mohammad; Virtue, Sam; Tuthill, Antoinette; Lefai, Etienne; Laville, Martine; Wu, Tingting; Considine, Robert V; Vidal, Hubert; Langin, Dominique; Oresic, Matej; Tinahones, Francisco J; Fernandez-Real, Jose Manuel; Griffin, Julian L; Sethi, Jaswinder K; López, Miguel; Vidal-Puig, Antonio

    2013-11-01

    The epidemic of obesity imposes unprecedented challenges on human adipose tissue (WAT) storage capacity that may benefit from adaptive mechanisms to maintain adipocyte functionality. Here, we demonstrate that changes in the regulatory feedback set point control of Insig1/SREBP1 represent an adaptive response that preserves WAT lipid homeostasis in obese and insulin-resistant states. In our experiments, we show that Insig1 mRNA expression decreases in WAT from mice with obesity-associated insulin resistance and from morbidly obese humans and in in vitro models of adipocyte insulin resistance. Insig1 downregulation is part of an adaptive response that promotes the maintenance of SREBP1 maturation and facilitates lipogenesis and availability of appropriate levels of fatty acid unsaturation, partially compensating the antilipogenic effect associated with insulin resistance. We describe for the first time the existence of this adaptive mechanism in WAT, which involves Insig1/SREBP1 and preserves the degree of lipid unsaturation under conditions of obesity-induced insulin resistance. These adaptive mechanisms contribute to maintain lipid desaturation through preferential SCD1 regulation and facilitate fat storage in WAT, despite on-going metabolic stress.

  15. Cocaine-induced changes of synaptic transmission in the striatum are modulated by adenosine A2A receptors and involve the tyrosine phosphatase STEP.

    Science.gov (United States)

    Chiodi, Valentina; Mallozzi, Cinzia; Ferrante, Antonella; Chen, Jiang F; Lombroso, Paul J; Di Stasi, Anna Maria Michela; Popoli, Patrizia; Domenici, Maria Rosaria

    2014-02-01

    The striatum is a brain area implicated in the pharmacological action of drugs of abuse. Adenosine A2A receptors (A2ARs) are highly expressed in the striatum and mediate, at least in part, cocaine-induced psychomotor effects in vivo. Here we studied the synaptic mechanisms implicated in the pharmacological action of cocaine in the striatum and investigated the influence of A2ARs. We found that synaptic transmission was depressed in corticostriatal slices after perfusion with cocaine (10 μM). This effect was reduced by the A2AR antagonist ZM241385 and almost abolished in striatal A2AR-knockout mice (mice lacking A2ARs in striatal neurons, stA2ARKO). The effect of cocaine on synaptic transmission was also prevented by the protein tyrosine phosphatases (PTPs) inhibitor sodium orthovanadate (Na3VO4). In synaptosomes prepared from striatal slices, we found that the activity of striatal-enriched protein tyrosine phosphatase (STEP) was upregulated by cocaine, prevented by ZM241385, and absent in synaptosomes from stA2ARKO. The role played by STEP in cocaine modulation of synaptic transmission was investigated in whole-cell voltage clamp recordings from medium spiny neurons of the striatum. We found that TAT-STEP, a peptide that renders STEP enzymatically inactive, prevented cocaine-induced reduction in AMPA- and NMDA-mediated excitatory post-synaptic currents, whereas the control peptide, TAT-myc, had no effect. These results demonstrate that striatal A2ARs modulate cocaine-induced synaptic depression in the striatum and highlight the potential role of PTPs and specifically STEP in the effects of cocaine.

  16. Open Access Transmission and Renewable Energy Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Porter, K.

    1996-09-01

    In April 1996, the Federal Regulatory Commission (PERC) approved Orders 888 and 889 and released a draft rule for public comment on capacity reservation tariffs (CRTs). Order No. 888 requires electric utilities to file transmission tariffs that would allow transmission access to third parties who want to conduct wholesale transactions, and Order No. 889 requires transmission-owning utilities to set up open access, same-time information systems (OASIS), using commercial software and Internet protocols. This paper discusses these Orders in detail, as well as some of the issues before FERC with implications for renewables, which include: transmission pricing; transmission terms and conditions; reassignment of transmission capacity; defining state and FERC jurisdiction over transmission and distribution; the pricing of ancillary services; and the adoption and implementation of independent system operators.

  17. Survey of Transmission Cost Allocation Methodologies for Regional Transmission Organizations

    Energy Technology Data Exchange (ETDEWEB)

    Fink, S.; Porter, K.; Mudd, C.; Rogers, J.

    2011-02-01

    The report presents transmission cost allocation methodologies for reliability transmission projects, generation interconnection, and economic transmission projects for all Regional Transmission Organizations.

  18. Transmission dynamics and resistance in staphylococci

    NARCIS (Netherlands)

    Hetem, D.J.

    2015-01-01

    This thesis will focus on nosocomial transmission and resistance of S. aureus and CoNS. After the general introduction on S. aureus and coagulase-negative staphylococci, part II focuses on the nosocomial transmission capacity of different MRSA clones in the hospital setting. In chapter 2 the nosocom

  19. Available transmission capacity assessment

    Directory of Open Access Journals (Sweden)

    Škokljev Ivan

    2012-01-01

    Full Text Available Effective power system operation requires the analysis of vast amounts of information. Power market activities expose power transmission networks to high-level power transactions that threaten normal, secure operation of the power system. When there are service requests for a specific sink/source pair in a transmission system, the transmission system operator (TSO must allocate the available transfer capacity (ATC. It is common that ATC has a single numerical value. Additionally, the ATC must be calculated for the base case configuration of the system, while generation dispatch and topology remain unchanged during the calculation. Posting ATC on the internet should benefit prospective users by aiding them in formulating their requests. However, a single numerical value of ATC offers little for prospect for analysis, planning, what-if combinations, etc. A symbolic approach to the power flow problem (DC power flow and ATC offers a numerical computation at the very end, whilst the calculation beforehand is performed by using symbols for the general topology of the electrical network. Qualitative analysis of the ATC using only qualitative values, such as increase, decrease or no change, offers some new insights into ATC evaluation, multiple transactions evaluation, value of counter-flows and their impact etc. Symbolic analysis in this paper is performed after the execution of the linear, symbolic DC power flow. As control variables, the mathematical model comprises linear security constraints, ATC, PTDFs and transactions. The aim is to perform an ATC sensitivity study on a five nodes/seven lines transmission network, used for zonal market activities tests. A relatively complicated environment with twenty possible bilateral transactions is observed.

  20. Microstructure changes during non-conventional heat treatment of thin Ni-Ti wires by pulsed electric current studied by transmission electron microscopy

    Energy Technology Data Exchange (ETDEWEB)

    Delville, R., E-mail: remi.delville@ua.ac.be [EMAT, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp (Belgium); Malard, B.; Pilch, J.; Sittner, P. [Institute of Physics, Na Slovance 2, 182 21 Praha (Czech Republic); Schryvers, D. [EMAT, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp (Belgium)

    2010-08-15

    Transmission electron microscopy, electrical resistivity measurements and mechanical testing were employed to investigate the evolution of microstructure and functional superelastic properties of 0.1 mm diameter as-drawn Ni-Ti wires subjected to a non-conventional heat treatment by controlled electric pulse currents. This method enables a better control of the recovery and recrystallization processes taking place during the heat treatment and accordingly a better control on the final microstructure. Using a stepwise approach of millisecond pulse annealing, it is shown how the microstructure evolves from a severely deformed state with no functional properties to an optimal nanograined microstructure (20-50 nm) that is partially recovered through polygonization and partially recrystallized and that has the best functional properties. Such a microstructure is highly resistant against dislocation slip upon cycling, while microstructures annealed for longer times and showing mostly recrystallized grains were prone to dislocation slip, particularly as the grain size exceeds 200 nm.

  1. Integration of prevention of mother-to-child transmission of HIV (PMTCT postpartum services with other HIV care and treatment services within the maternal and child health setting in Zimbabwe, 2012.

    Directory of Open Access Journals (Sweden)

    Katherine Wiegert

    Full Text Available We assessed the integration of PMTCT services during the postpartum period including early infant diagnosis of HIV (EID and adult and pediatric antiretroviral therapy (ART in maternal and child health (MCH facilities in Zimbabwe.From August to December 2012 we conducted a cross-sectional survey of a nationally representative sample of 151 MCH facilities. A questionnaire was used to survey each site about staff training, dried blood spot sample (DBS collection, turnaround time (TAT for test results, PMTCT services, and HIV care and treatment linkages for HIV-infected mothers and children and HIV-exposed infants. Descriptive analyses were used. Of the facilities surveyed, all facilities were trained on DBS collection and 92% responded. Approximately, 99% of responding facilities reported providing DBS collection and a basic HIV-exposed infant service package including EID, extended nevirapine prophylaxis, and use of cotrimoxazole. DBS collection was integrated with immunisations at 83% of facilities, CD4 testing with point-of-care machines was available at 37% of facilities, and ART for both mothers and children was provided at 27% of facilities. More than 80% of facilities reported that DBS test results take >4 weeks to return; TAT did not have a direct association with any specific type of transport, distance to the lab, or intermediate stops for data to travel.Zimbabwe has successfully scaled up and integrated the national EID and PMTCT programs into the existing MCH setting. The long TAT of infant DBS test results and the lack of integrated ART programs in the MCH setting could reduce effectiveness of the national PMTCT and ART programs. Addressing these important gaps will support successful implementation of the 2014 Zimbabwe's PMTCT guidelines under which all HIV-infected pregnant and breastfeeding women will be offered life-long ART and decentralized ART care.

  2. Constructive Sets in Computable Sets

    Institute of Scientific and Technical Information of China (English)

    傅育熙

    1997-01-01

    The original interpretation of the constructive set theory CZF in Martin-Loef's type theory uses the‘extensional identity types’.It is generally believed that these‘types’do not belong to type theory.In this paper it will be shown that the interpretation goes through without identity types.This paper will also show that the interpretation can be given in an intensional type theory.This reflects the computational nature of the interpretation.This computational aspect is reinforced by an ω-Set moel of CZF.

  3. Transmission eigenvalues for operators with constant coefficients

    CERN Document Server

    Hitrik, Michael; Ola, Petri; Päivärinta, Lassi

    2010-01-01

    In this paper we study the interior transmission problem and transmission eigenvalues for multiplicative perturbations of linear partial differential operator of order $\\ge 2$ with constant real coefficients. Under suitable growth conditions on the symbol of the operator and the perturbation, we show the discreteness of the set of transmission eigenvalues and derive sufficient conditions on the existence of transmission eigenvalues. We apply these techniques to the case of the biharmonic operator and the Dirac system. In the hypoelliptic case we present a connection to scattering theory.

  4. Harmonics in transmission power systems

    DEFF Research Database (Denmark)

    Wiechowski, Wojciech Tomasz

    in transmission power systems" was formulated. In this project, the entire 400 kV and 150 kV western transmission network of Energinet.dk is modelled using the simulation software DIgSILENT PowerFactory. A fundamental frequency load-flow model is used as a basis that is to be extended. The model is sought......, provided that background harmonic distortion, and the network configuration, are not changing during the measurement. It is shown that switching of a shunt linear power system component can result in variation of the harmonic levels that can be measured and used to verify the harmonic model of the network......, in order to determine which power system component, when switched, results in the largest change in harmonic levels, some initial harmonic simulations, using the created harmonic model of Energinet.dk transmission network, are performed. The criterion is that the measuring equipment shall not be installed...

  5. Measurement of magnetic moment via optical transmission

    Energy Technology Data Exchange (ETDEWEB)

    Heidsieck, Alexandra, E-mail: aheidsieck@tum.de; Schmid, Daniel; Gleich, Bernhard

    2016-03-01

    The magnetic moment of nanoparticles is an important property for drug targeting and related applications as well as for the simulation thereof. However, the measurement of the magnetic moment of nanoparticles, nanoparticle–virus-complexes or microspheres in solution can be difficult and often yields unsatisfying or incomparable results. To measure the magnetic moment, we designed a custom measurement device including a magnetic set-up to observe nanoparticles indirectly via light transmission in solution. We present a simple, cheap device of manageable size, which can be used in any laboratory as well as a novel evaluation method to determine the magnetic moment of nanoparticles via the change of the optical density of the particle suspension in a well-defined magnetic gradient field. In contrast to many of the established measurement methods, we are able to observe and measure the nanoparticle complexes in their natural state in the respective medium. The nanoparticles move along the magnetic gradient and thereby away from the observation point. Due to this movement, the optical density of the fluid decreases and the transmission increases over time at the measurement location. By comparing the measurement with parametric simulations, we can deduce the magnetic moment from the observed behavior. - Highlights: • Performance of a direct detection camera in the context of off-axis electron holography has been evaluated. • A measurement device to indirectly observe magnetic nanoparticles (MNPs) is described. • MNPs can be observed in the respective medium via light transmission. • An evaluation method to determine the magnetic moment of the MNPs is presented. • The magnetic moment can be deduced from the observed change in optical density.

  6. Impact of climate change and man-made irrigation systems on the transmission risk, long-term trend and seasonality of human and animal fascioliasis in Pakistan

    Directory of Open Access Journals (Sweden)

    Kiran Afshan

    2014-05-01

    Full Text Available Large areas of the province of Punjab, Pakistan are endemic for fascioliasis, resulting in high economic losses due to livestock infection but also affecting humans directly. The prevalence in livestock varies pronouncedly in space and time (1-70%. Climatic factors influencing fascioliasis presence and potential spread were analysed based on data from five mete- orological stations during 1990-2010. Variables such as wet days (Mt, water-budget-based system (Wb-bs indices and the normalized difference vegetation index (NDVI, were obtained and correlated with geographical distribution, seasonality patterns and the two-decade evolution of fascioliasis in livestock throughout the province. The combined approach by these three indices proved to furnish a useful tool to analyse the complex epidemiology that includes (i sheep-goats and cattle- buffaloes presenting different immunological responses to fasciolids; (ii overlap of Fasciola hepatica and F. gigantica; (iii co-existence of highlands and lowlands in the area studied; and (iv disease transmission following bi-seasonality with one peak related to natural rainfall and another peak related to man-made irrigation. Results suggest a human infection situa- tion of concern and illustrate how climate and anthropogenic environment modifications influence both geographical dis- tribution and seasonality of fascioliasis risks. Increased fascioliasis risk throughout the Punjab plain and its decrease in the northern highlands of the province became evident during the study period. The high risk in the lowlands is worrying given that Punjab province largely consists of low-altitude, highly irrigated plains. The importance of livestock in this province makes it essential to prioritise adequate control measures. An annual treatment scheme to control the disease is recom- mended to be applied throughout the whole province.

  7. Impact of climate change and man-made irrigation systems on the transmission risk, long-term trend and seasonality of human and animal fascioliasis in Pakistan.

    Science.gov (United States)

    Afshan, Kiran; Fortes-Lima, Cesar A; Artigas, Patricio; Valero, Adela M; Qayyum, Mazhar; Mas-Coma, Santiago

    2014-05-01

    Large areas of the province of Punjab, Pakistan are endemic for fascioliasis, resulting in high economic losses due to livestock infection but also affecting humans directly. The prevalence in livestock varies pronouncedly in space and time (1-70%). Climatic factors influencing fascioliasis presence and potential spread were analysed based on data from five meteorological stations during 1990-2010. Variables such as wet days (Mt), water-budget-based system (Wb-bs) indices and the normalized difference vegetation index (NDVI), were obtained and correlated with geographical distribution, seasonality patterns and the two-decade evolution of fascioliasis in livestock throughout the province. The combined approach by these three indices proved to furnish a useful tool to analyse the complex epidemiology that includes (i) sheep-goats and cattlebuffaloes presenting different immunological responses to fasciolids; (ii) overlap of Fasciola hepatica and F. gigantica; (iii) co-existence of highlands and lowlands in the area studied; and (iv) disease transmission following bi-seasonality with one peak related to natural rainfall and another peak related to man-made irrigation. Results suggest a human infection situation of concern and illustrate how climate and anthropogenic environment modifications influence both geographical distribution and seasonality of fascioliasis risks. Increased fascioliasis risk throughout the Punjab plain and its decrease in the northern highlands of the province became evident during the study period. The high risk in the lowlands is worrying given that Punjab province largely consists of low-altitude, highly irrigated plains. The importance of livestock in this province makes it essential to prioritise adequate control measures. An annual treatment scheme to control the disease is recommended to be applied throughout the whole province.

  8. Epidemiology of Infant Dengue Cases Illuminates Serotype-Specificity in the Interaction between Immunity and Disease, and Changes in Transmission Dynamics.

    Directory of Open Access Journals (Sweden)

    Hannah Clapham

    2015-12-01

    Full Text Available Infants born to dengue immune mothers acquire maternal antibodies to dengue. These antibodies, though initially protective, decline during the first year of life to levels thought to be disease enhancing, before reaching undetectable levels. Infants have long been studied to understand the interaction between infection and disease on an individual level.Considering infants (cases <1 year old as a unique group, we analyzed serotype specific dengue case data from patients admitted to a pediatric hospital in Bangkok, Thailand. We show differences in the propensity of serotypes to cause disease in individuals with dengue antibodies (infants and post-primary cases and in individuals without dengue antibodies (primary cases. The mean age of infant cases differed among serotypes, consistent with previously observed differential waning of maternal antibody titers by serotype. We show that trends over time in epidemiology of infant cases are consistent with those observed in the whole population, and therefore with trends in the force of infection.Infants with dengue are informative about the interaction between antibody and the dengue serotypes, confirming that in this population DENV-2 and DENV-4 almost exclusively cause disease in the presence of dengue antibody despite infections occurring in others. We also observe differences between the serotypes in the mean age in infant cases, informative about the interaction between waning immunity and disease for the different serotypes in infants. In addition, we show that the mean age of infant cases over time is informative about transmission in the whole population. Therefore, ongoing surveillance for dengue in infants could provide useful insights into dengue epidemiology, particularly after the introduction of a dengue vaccine targeting adults and older children.

  9. 基于随机游走模型的质量信息传递的焓变机制研究%Research on Enthalpy Change Mechanism of Quality Information Transmission Based on Random Walk Model

    Institute of Scientific and Technical Information of China (English)

    史丽萍; 唐书林; 刘强; 苑婧婷

    2012-01-01

    Considering the different perception ability for quality information by different customers, the paper argued "enthalpy" in physics, defined the fluctuation of customs' perception value caused by quality information as enthalpy change of quality information transmission, and that enthalpy change of quality information was the key indicator of describing quality evolution. The paper adopted random walk model to establish enthalpy change model of quality different times, further discovered the time and space of enthalpy change. Research results indicated that enthalpy change of quality information transmission obeyed Gaussian distribution, whose convergence was proportional to perception ability of quality information by customer. Positive enthalpy change could increase customer' s perception value, which would purchase desire; negative enthalpy change would cause "enthalpy black hole" of customer' s perception value, which would betoken the occurrence of quality crisis. Comparing the enthalpy and price of different times Could identify the development stage and affecting region of quality crisis, which would provide distinguishing basis for enterprise decision.%从顾客对质量信息的感知能力差异出发,本文认为质量信息的传递会导致顾客感知价值呈现波动性,因此引入物理学中"焓"的概念,将因质量信息引起顾客感知价值的波动定义为"质量信息传递的焓变",认为质量信息的焓变是描述质量演变的关键性指标.本文利用随机游走理论建立了质量信息传递的焓变模型来描述同一时间不同顾客、同一顾客不同时间的焓,发现焓变的时间和空间.研究结果表明质量信息传递的焓变服从高斯分布,其收敛性跟顾客对质量信息的感知能力成正比.正焓变会增加顾客感知价值,提升购买欲望;负焓变会使顾客感知价值出现"焓黑洞",预示着质量危机的发生.对比不同时刻的焓和价格可以识别出质量危机

  10. Attributing the impacts of land-cover changes in temperate regions on surface temperature and heat fluxes to specific causes: Results from the first LUCID set of simulations

    NARCIS (Netherlands)

    Boisier, J.P.; Noblet-Ducoudré, de N.; Pitman, A.J.; Cruz, F.T.; Delire, C.; Hurk, van den B.J.J.M.; Molen, van der M.K.; Müller, C.; Voldoire, A.

    2012-01-01

    Surface cooling in temperate regions is a common biogeophysical response to historical Land-Use induced Land Cover Change (LULCC). The climate models involved in LUCID show, however, significant differences in the magnitude and the seasonal partitioning of the temperature change. The LULCC-induced c

  11. Clustering, climate and dengue transmission.

    Science.gov (United States)

    Junxiong, Pang; Yee-Sin, Leo

    2015-06-01

    Dengue is currently the most rapidly spreading vector-borne disease, with an increasing burden over recent decades. Currently, neither a licensed vaccine nor an effective anti-viral therapy is available, and treatment largely remains supportive. Current vector control strategies to prevent and reduce dengue transmission are neither efficient nor sustainable as long-term interventions. Increased globalization and climate change have been reported to influence dengue transmission. In this article, we reviewed the non-climatic and climatic risk factors which facilitate dengue transmission. Sustainable and effective interventions to reduce the increasing threat from dengue would require the integration of these risk factors into current and future prevention strategies, including dengue vaccination, as well as the continuous support and commitment from the political and environmental stakeholders.

  12. Assessing motivation and readiness to change for weight management and control: an in-depth evaluation of three sets of instruments.

    Directory of Open Access Journals (Sweden)

    Martina eCeccarini

    2015-05-01

    Full Text Available It is highly recommended to promptly assess motivation and readiness to change in individuals who wish to achieve significant lifestyle behavior changes in order to improve their health, overall quality of life and well-being. In particular, motivation should be assessed for those who face the difficult task to maintain weight, which implies a double challenge: weight loss initially and its management subsequently. In fact, weight-control may be as problematic as smoking or drugs-taking cessation, since they all share the commonality of being highly refractory to change behaviors. This paper will examine three well-established tools following the Trans-theoretical Model (TTM, specifically assessing readiness to change in weight management: the URICA, the S-Weight and the P-Weight and the Decisional Balance Inventory. Though their strengths and weaknesses may appear to be rather homogeneous and similar, the S-Weight and P-Weight are more efficient in assessing readiness to change in weight management and control. Assessing motivation and readiness to change may be a crucial step in promptly identifying psychological obstacles or resistance towards weight-management in overweight or obese hospitalised individuals, and it may contribute to provide a more effective weight-control treatment intervention.

  13. Changes in the epithelium of the vaginal complex during the estrous cycle of the marsupial Monodelphis domestica. 1. Transmission electron microscopy study.

    Science.gov (United States)

    Regli, Christian; Kress, Annetrudi

    2002-01-01

    The vaginal complex of marsupials differs from that of eutherians. Cervices open separately in a sinus vaginalis or cul-de-sac. Two lateral vaginae adjoin the sinus vaginalis and fuse at the level of the urethra opening and form the sinus urogenitalis. During the estrous cycle the vaginal epithelium undergoes a number of specified morphological changes. This paper is the first to describe these changes on an ultrastructural level in a marsupial. Investigations in Monodelphis vagina reveal that a cyclic switch exists between a keratinized and a stratified nonkeratinized epithelium. Keratinization starts during proestrus and reaches its maximum during estrus. In the postestrus, desquamation of the stratum corneum takes place, mostly in two steps. In metestrus one to two additional layers of the now nonkeratinized surface cells are shed into the vaginal lumen. Typical cell structures, such as keratin filaments, keratohyalin and membrane-coating granules, are involved in the keratinization process. Keratohyalin is found in the cytoplasm as well as in the nucleus of stratum granulosum cells, a phenomenon which is known from other parakeratinized epithelia of rapid turnover. Membrane-coating granules, responsible for the permeability barrier between the epithelial cells, are of the nonlamellated type in the nonkeratinized epithelium and produce an amorphous material in the intercellular spaces after extrusion. At periods, however, when the epithelium is keratinized, membrane-coating granules are of the lamellated type and form a lamellated barrier structure after extrusion in the intercellular space. The loss of the protective keratinized layers asks for an additional defense mechanism for the epithelium. The migration of leukocytes through the epithelium predominantly during post- and metestrus and their presence in the vaginal lumen may play a protective role together with the bacterial content.

  14. The automotive transmission book

    CERN Document Server

    Fischer, Robert; Jürgens, Gunter; Najork, Rolf; Pollak, Burkhard

    2015-01-01

    This book presents essential information on systems and interactions in automotive transmission technology and outlines the methodologies used to analyze and develop transmission concepts and designs. Functions of and interactions between components and subassemblies of transmissions are introduced, providing a basis for designing transmission systems and for determining their potentials and properties in vehicle-specific applications: passenger cars, trucks, buses, tractors, and motorcycles. With these fundamentals the presentation provides universal resources for both state-of-the-art and future transmission technologies, including systems for electric and hybrid electric vehicles.

  15. Studies on transmission property changes of optical fibers inside an OPGW heated by conducting or discharge currents; OPGW tsuden/hoden kanetsu ni yoru hikari denso tokusei hendo no kento (sodensen kanshi hoho no chosa kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    Yamashita, I.; Seikai, S.; Takenaka, T. [Kansai Elecatric Power Co. Inc., Osaka (Japan)

    1999-09-30

    Temperature of OPGW's is known to increase due to thunderbolt. Therefore, the measurement of transmission characteristic changes of optical fibers inside the OPGW is seems to be useful method to supervise the electric power sending systems. Candidates for the detectable characteristics are optical loss, Brilloum frequency shift and Raman scattering power because distribution of these changes can be measured by OTDR techniques. In this experiments, those properties are investigated using a high voltage supply system at the Central Research Institute of Electric Power Industry. A test OPGW containing 24 fibers including 22 single-mode and 2 multi-mode fibers is installed with a span length of 20m. In the current conducting test, the OPGW is heated up to 250 degree C through three times conduction of 6kA with each duration time of 600 or 700ms. In the discharge current test, electric charge of 50C(coulomb), 100C and 200C with 20ms duration are applied. The results of the experiments are summarized as follows. The optical loss change is negligible small except for the fiber brake case and the Brilloum frequency shift is not always suitable because the sensitivity is small. The temperature measurement by the Raman scattering observation using the multi-mode fibers is found to have enough sensitivity and accuracy. However, residual problem is to increase the sensitivity of it for single mode fibers. (author)

  16. Bordetella pertussis transmission.

    Science.gov (United States)

    Trainor, Elizabeth A; Nicholson, Tracy L; Merkel, Tod J

    2015-11-01

    Bordetella pertussis and B. bronchiseptica are Gram-negative bacterial respiratory pathogens. Bordetella pertussis is the causative agent of whooping cough and is considered a human-adapted variant of B. bronchiseptica. Bordetella pertussis and B. bronchiseptica share mechanisms of pathogenesis and are genetically closely related. However, despite the close genetic relatedness, these Bordetella species differ in several classic fundamental aspects of bacterial pathogens such as host range, pathologies and persistence. The development of the baboon model for the study of B. pertussis transmission, along with the development of the swine and mouse model for the study of B. bronchiseptica, has enabled the investigation of different aspects of transmission including the route, attack rate, role of bacterial and host factors, and the impact of vaccination on transmission. This review will focus on B. pertussis transmission and how animal models of B. pertussis transmission and transmission models using the closely related B. bronchiseptica have increased our understanding of B. pertussis transmission.

  17. Determining Robust Impacts of Land-Use-Induced Land Cover Changes on Surface Temperature over China and surrounding regions: Results from the First Set of LUCID Experiments

    Science.gov (United States)

    Xiang, Zheng; Guo, Weidong

    2016-04-01

    The project Land-Use and Climate, Identification of Robust Impacts (LUCID) was designed to address the robustness of biogeophysical impacts of historical land use-land cover change (LULCC). LUCID used seven atmosphere-land models with a common experimental design to explore those impacts of LULCC that are robust and consistent across the climate models. The biogeophysical impacts of LULCC were also compared to the impact of elevated greenhouse gases and resulting changes in sea surface temperatures and sea ice extent (hereafter SST/CO2). Focusing the analysis on China and surrounding regions, the climate models involved in LUCID show, however, significant differences in the magnitude and the seasonal partitioning of the temperature change. The LULCC-induced cooling is directed by decreases in absorbed solar radiation, but its amplitude is 30 to 50% smaller than the one that would be expected from the sole radiative changes. This results from direct impacts on the total turbulent energy flux (related to changes in land-cover properties other than albedo, such as evapotranspiration efficiency or surface roughness) that decreases at all seasons, and thereby induces a relative warming in all models. The magnitude of those processes varies significantly from model to model, resulting on different climate responses to LULCC.

  18. [Changes in the prekeratin set and in the intracellular distribution of intermediate filaments during the embryonic development of the liver in the rat].

    Science.gov (United States)

    Chipysheva, T A; Gel'shteĭn, V I; Troianovskiĭ, S M; Bannikov, G A

    1988-01-01

    Monoclonals against three individual proteins of the epithelial intermediate filaments, prekeratins (PK40, PK49, PK55), were used for immunofluorescence studies of the cryostat sections of the rat embryonic liver. The dynamics of expression and intracellular distribution of prekeratins reflects that of morphological rearrangement of the liver. The development of the system of liver beams was accompanied by changes in the expression and intracellular distribution of PK49 and PK55 and the development of the system of bile ducts by changes in all three PKs. From day 20-21 of embryogenesis all three PKs are expressed in cholangiocytes, while PK49 and PK55 in hepatocytes only.

  19. Modelling the impact of artemisinin combination therapy and long-acting treatments on malaria transmission intensity.

    Directory of Open Access Journals (Sweden)

    Lucy C Okell

    2008-11-01

    Full Text Available BACKGROUND: Artemisinin derivatives used in recently introduced combination therapies (ACTs for Plasmodium falciparum malaria significantly lower patient infectiousness and have the potential to reduce population-level transmission of the parasite. With the increased interest in malaria elimination, understanding the impact on transmission of ACT and other antimalarial drugs with different pharmacodynamics becomes a key issue. This study estimates the reduction in transmission that may be achieved by introducing different types of treatment for symptomatic P. falciparum malaria in endemic areas. METHODS AND FINDINGS: We developed a mathematical model to predict the potential impact on transmission outcomes of introducing ACT as first-line treatment for uncomplicated malaria in six areas of varying transmission intensity in Tanzania. We also estimated the impact that could be achieved by antimalarials with different efficacy, prophylactic time, and gametocytocidal effects. Rates of treatment, asymptomatic infection, and symptomatic infection in the six study areas were estimated using the model together with data from a cross-sectional survey of 5,667 individuals conducted prior to policy change from sulfadoxine-pyrimethamine to ACT. The effects of ACT and other drug types on gametocytaemia and infectiousness to mosquitoes were independently estimated from clinical trial data. Predicted percentage reductions in prevalence of infection and incidence of clinical episodes achieved by ACT were highest in the areas with low initial transmission. A 53% reduction in prevalence of infection was seen if 100% of current treatment was switched to ACT in the area where baseline slide-prevalence of parasitaemia was lowest (3.7%, compared to an 11% reduction in the highest-transmission setting (baseline slide prevalence = 57.1%. Estimated percentage reductions in incidence of clinical episodes were similar. The absolute size of the public health impact

  20. Essays in financial transmission rights pricing

    Science.gov (United States)

    Posner, Barry

    This work examines issues in the pricing of financial transmission rights in the PJM market region. The US federal government is advocating the creation of large-scale, not-for-profit regional transmission organizations to increase the efficiency of the transmission of electricity. As a non-profit entity, PJM needs to allocate excess revenues collected as congestion rents, and the participants in the transmission markets need to be able to hedge their exposure to congestion rents. For these purposes, PJM has developed an instrument known as the financial transmission right (FTR). This research, utilizing a new data set assembled by the author, looks at two aspects of the FTR market. The first chapter examines the problem of forecasting congestion in a transmission grid. In the PJM FTR system firms bid in a competitive auction for FTRs that cover a period of one month. The auctions take place in the middle of the previous month; therefore firms have to forecast congestion rents for the period two to six weeks after the auction. The common methods of forecasting congestion are either time-series models or full-information engineering studies. In this research, the author develops a forecasting system that is more economically grounded than a simple time-series model, but requires less information than an engineering model. This method is based upon the arbitrage-cost methodology, whereby congesting is calculated as the difference of two non-observable variables: the transmission price difference that would exist in the total absence of transmission capacity between two nodes, and the ability of the existing transmission to reduced that price difference. If the ability to reduce the price difference is greater than the price difference, then the cost of electricity at each node will be the same, and congestion rent will be zero. If transmission capacity limits are binding on the flow of power, then a price difference persists and congestion rents exist. Three

  1. Analysis of Wireless Power Transmission

    OpenAIRE

    2013-01-01

    The advent of various wireless technologies have revolutionized the communication infrastructure and consequently changed the entire world into a global village. Use of wireless technology has also been made for transmission of electric power wirelessly. It increases the portability of power systems and integrates the communication technologies and electric power to the same platform. This paper presents a comprehensive review and detailed analysis of various techniques used for wireless powe...

  2. Trajectories of Life Satisfaction: Positive Feedback Loops May Explain Why Life Satisfaction Changes in Multi-year Waves Rather than Oscillating around a Set-Point

    OpenAIRE

    Headey, Bruce; Muffels, Ruud J.A.

    2014-01-01

    Long term panel data enable researchers to construct Life Satisfaction (LS) trajectories for individuals over time. In this paper we analyse the trajectories of respondents in the German Socio-Economic Panel who recorded their LS for 20 consecutive years in 1991 - 2010. Previous research has shown that at least a quarter of these respondents recorded substantial long term changes in LS (Headey, Muffels and Wagner, 2010, 2012). In this paper, bar charts of LS trajectories, and subsequent stati...

  3. Self-reported alcohol intake is a better estimate of 5-year change in blood pressure than biochemical markers in low resource settings: the PURE study

    OpenAIRE

    Zatu, Mandlenkosi C.; Van Rooyen, Johannes M.; Du Toit, Loots; Wentzel-Viljoen, Edelweiss; Greeff, Minrie; Schutte, Aletta E.

    2014-01-01

    Background: Despite criticism of self-reported alcohol intake, it is a valuable tool to screen for alcohol abuse as a risk factor for cardiovascular disease. We aimed to compare various self-reported estimates of alcohol use with γ-glutamyltransferase (GGT) and percentage carbohydrate deficient transferrin (%CDT) considering their relationship with blood pressure changes (%BP) over a 5-year period in black South Africans. Method: We recruited 1994 participants and collected 5-year followe...

  4. Bilateral Achilles Tendon Ruptures Associated With Ciprofloxacin Use in the Setting of Minimal Change Disease: Case Report and Review of the Literature.

    Science.gov (United States)

    Kawtharani, Firas; Masrouha, Karim Z; Afeiche, Nadim

    2016-01-01

    Fluoroquinolones are widely used antibiotics; however, numerous side effects have been reported in published studies, including a spectrum of tendinopathies, affecting numerous anatomic sites. Several risk factors have been identified, including advanced age (>60 years), corticosteroid use, renal failure or dialysis, female sex, and nonobesity. We present the case of an elderly male with minimal change disease treated with glucocorticoids and acute kidney injury, who sustained spontaneous nontraumatic bilateral Achilles tendon tears 4 days after initiating ciprofloxacin.

  5. 互感线路接地距离保护定值灵敏度影响分析及其整定优化%Sensitivity Impact Analysis and Optimal Setting of Grounding Distance Protection of Transmission Lines with Mutual Inductance

    Institute of Scientific and Technical Information of China (English)

    邱建; 曾耿晖; 李一泉; 陈志光; 屠卿瑞; 张葆红

    2015-01-01

    A complete detecting impedance analysis model of transmission lines with mutual inductance is developed from the angle of setting.In the model,the influence mechanism of various factors on the measured impendence of grounding distance protection is qualitatively analyzed and quantitatively validated.With these results,the conditions for the simplified model which can calculate the extreme values of the measured impendence are proposed.On this basis and by referring to typical extreme value cases in the power system,the sideline current addition influence of the detecting impendence of transmission lines with mutual inductance is further analyzed.Finally,the optimal relay setting strategy for the grounding distance protection based on the analysis results is proposed.The strategy is implemented in Guangdong power grid.Actual application results show that the optimal strategy is able to improve the adaptability and performance of grounding distance protection.%从整定的角度建立互感线路感受阻抗分析完整模型,并对模型中各因素影响互感线路接地距离保护测量阻抗的机理进行定性分析和定量验证,提出了求取测量阻抗极值的简化模型条件。在此基础上结合电网中典型极值工况进一步对互感线路感受阻抗的助增影响进行分析。最后,根据分析结论提出了接地距离保护定值的整定优化策略,该整定策略已在广东电网全面应用,实际应用结果表明该整定策略能够提高接地距离保护定值的适应性,改善了接地距离保护定值的性能。

  6. Understanding ebola virus transmission.

    Science.gov (United States)

    Judson, Seth; Prescott, Joseph; Munster, Vincent

    2015-02-03

    An unprecedented number of Ebola virus infections among healthcare workers and patients have raised questions about our understanding of Ebola virus transmission. Here, we explore different routes of Ebola virus transmission between people, summarizing the known epidemiological and experimental data. From this data, we expose important gaps in Ebola virus research pertinent to outbreak situations. We further propose experiments and methods of data collection that will enable scientists to fill these voids in our knowledge about the transmission of Ebola virus.

  7. Synthesising 30 years of mathematical modelling of Echinococcus transmission.

    Directory of Open Access Journals (Sweden)

    Jo-An M Atkinson

    Full Text Available BACKGROUND: Echinococcosis is a complex zoonosis that has domestic and sylvatic lifecycles, and a range of different intermediate and definitive host species. The complexities of its transmission and the sparse evidence on the effectiveness of control strategies in diverse settings provide significant challenges for the design of effective public health policy against this disease. Mathematical modelling is a useful tool for simulating control packages under locally specific transmission conditions to inform optimal timing and frequency of phased interventions for cost-effective control of echinococcosis. The aims of this review of 30 years of Echinococcus modelling were to discern the epidemiological mechanisms underpinning models of Echinococcus granulosus and E. multilocularis transmission and to establish the need to include a human transmission component in such models. METHODOLOGY/PRINCIPAL FINDINGS: A search was conducted of all relevant articles published up until July 2012, identified from the PubMED, Web of Knowledge and Medline databases and review of bibliographies of selected papers. Papers eligible for inclusion were those describing the design of a new model, or modification of an existing mathematical model of E. granulosus or E. multilocularis transmission. A total of 13 eligible papers were identified, five of which described mathematical models of E. granulosus and eight that described E. multilocularis transmission. These models varied primarily on the basis of six key mechanisms that all have the capacity to modulate model dynamics, qualitatively affecting projections. These are: 1 the inclusion of a 'latent' class and/or time delay from host exposure to infectiousness; 2 an age structure for animal hosts; 3 the presence of density-dependent constraints; 4 accounting for seasonality; 5 stochastic parameters; and 6 inclusion of spatial and risk structures. CONCLUSIONS/SIGNIFICANCE: This review discusses the conditions under

  8. ClimateQUAL® and Thinklets: Using ClimateQUAL® with Group Support Systems to Facilitate Discussion and Set Priorities for Organizational Change at Criss Library

    Directory of Open Access Journals (Sweden)

    Nora Hillyer

    2013-06-01

    Full Text Available Objective – This article discusses a series of actions taken by the Criss Library at the University of Nebraska at Omaha to implement organizational change, using the ClimateQUAL® survey and facilitated discussions with ThinkTank™ group decision software. The library had experienced significant changes over a five-year period, with a renovation of the facility and three reorganizations resulting in a 50% staff turnover. Recognizing the strain that years of construction and personnel changes had placed on the organization, there was a desire to uncover the mood of the employees and reveal the issues behind low morale, uneasiness, and fear.Methods – In November 2009, the library conducted a ClimateQUAL® survey to develop a baseline to assess the effectiveness of any changes. After the results were distributed to library faculty and staff, a series of two-hour facilitated discussions was held to gather opinions and ideas for solutions using thinkLets, a pattern language for reasoning toward a goal. The group support system ThinkTank™ software was loaded onto computers, and employees were able to add their ideas anonymously during the sessions. Finally, 12 employees (29% completed a four-question survey on their perceptions of the facilitated discussions.Results – The facilitated discussions returned 76 sub-themes in 12 categories: staffing and scheduling issues, staff unity/teamwork, communication, goodwill/morale, accountability, decision-making, policy issues, skills and training, leadership, ergonomics/physical work environment, respect, and bullying. An advisory team culled the 76 sub-themes into 40 improvement strategies. Five were implemented immediately, and the remaining 35 were scheduled to be presented to the faculty and staff via an online survey. Participants’ perceptions of the facilitated discussions were mixed. Eighty-three percent of respondents reported that they did not feel safe speaking out about issues, most

  9. Comparison of Hounsfield units by changing in size of physical area and setting size of region of interest by using the CT phantom made with a 3D printer

    Energy Technology Data Exchange (ETDEWEB)

    Seung, Youl Hun [Dept. of Radiological Science, Cheongju University, Cheongju (Korea, Republic of)

    2015-12-15

    In this study, we have observed the change of the Hounsfield (HU) in the alteration of by changing in size of physical area and setting size of region of interest (ROI) at focus on kVp and mAs. Four-channel multi-detector computed tomography was used to get transverse axial scanning images and HU. Three dimensional printer which is type of fused deposition modeling (FDM) was used to produce the Phantom. The structure of the phantom was designed to be a type of cylinder that contains 33 mm, 24 mm, 19 mm, 16 mm, 9 mm size of circle holes that are symmetrically located. It was charged with mixing iodine contrast agent and distilled water in the holes. The images were gained with changing by 90 kVp, 120 kVp, 140 kVp and 50 mAs, 100 mAs, 150 mAs, respectively. The ‘image J’ was used to get the HU measurement of gained images of ROI. As a result, it was confirmed that kVp affects to HU more than mAs. And it is suggested that the smaller size of physical area, the more decreasing HU even in material of a uniform density and the smaller setting size of ROI, the more increasing HU. Therefore, it is reason that to set maximum ROI within 5 HU is the best way to minimize in the alteration of by changing in size of physical area and setting size of region of interest.

  10. Transmission system planning in Ontario

    Energy Technology Data Exchange (ETDEWEB)

    Barrie, D.; Macedo, F.X.; Mcconnach, J.S. [Ontario Hydro, Toronto, ON (Canada)

    1994-12-31

    In recent years, new and modified approaches to planning the large transmission system that serves the province of Ontario, Canada, have been necessary to accommodate the rapidly changing planning environment including slower uncertain growth, ageing of facilities, integration of demand side management and non utility generation options, increased competitiveness, increased financial stresses and affordable constraints. This paper describes some of the new and modified approaches and tools that have been adopted or are being developed by Ontario Hydro to cope with this changing environment. (author) 9 refs., 4 figs.

  11. Self-Adaptive Matching Method of Signal and Energy Transmission

    Institute of Scientific and Technical Information of China (English)

    李杰; 曲秀杰; 李喆; 张峰

    2003-01-01

    Aimed at the rapid message setting of the passive systems, the efficiency of energy transmission and the characteristics of signal transmission in the message setting are analyzed, which is based on the methods of the circuit analysis and the electromagnetic induction technology. A self-adaptive impedance matching method of signal and energy transmission, which can set the message rapidly and effectively, is put forward. The electromagnetic induct setting system will reach the highest energy transmission efficiency when the equivalent resistance of the second loop is equal to the resistance of the first loop. The greater the ratio of the equivalent resistances is, the higher efficient the signal transmission has. Moreover, the validity of the method is verified by circuit design and tests.

  12. Cultural Transmission of Civicness

    DEFF Research Database (Denmark)

    Ljunge, Jan Martin

    This paper estimates the intergeneration transmission of civicness by studying second generation immigrants in 29 European countries with ancestry in 83 nations. There is significant transmission of civicness both on the mother’s and the father’s side. The estimates are quantitatively significant...

  13. Interspecies transmission of prions.

    Science.gov (United States)

    Afanasieva, E G; Kushnirov, V V; Ter-Avanesyan, M D

    2011-12-01

    Mammalian prions are infectious agents of proteinaceous nature that cause several incurable neurodegenerative diseases. Interspecies transmission of prions is usually impeded or impossible. Barriers in prion transmission are caused by small interspecies differences in the primary structure of prion proteins. The barriers can also depend on the strain (variant) of a transmitted prion. Interspecies barriers were also shown for yeast prions, which define some heritable phenotypes. Yeast prions reproduce all the main traits of prion transmission barriers observed for mammals. This allowed to show that the barrier in prion transmission can be observed even upon copolymerization of two prionogenic proteins. Available data allow elucidation of the mechanisms that impede prion transmission or make it impossible.

  14. Nonlinear magnetoinductive transmission lines

    CERN Document Server

    Lazarides, Nikos; Tsironis, G P

    2011-01-01

    Power transmission in one-dimensional nonlinear magnetic metamaterials driven at one end is investigated numerically and analytically in a wide frequency range. The nonlinear magnetic metamaterials are composed of varactor-loaded split-ring resonators which are coupled magnetically through their mutual inductances, forming thus a magnetoiductive transmission line. In the linear limit, significant power transmission along the array only appears for frequencies inside the linear magnetoinductive wave band. We present analytical, closed form solutions for the magnetoinductive waves transmitting the power in this regime, and their discrete frequency dispersion. When nonlinearity is important, more frequency bands with significant power transmission along the array may appear. In the equivalent circuit picture, the nonlinear magnetoiductive transmission line driven at one end by a relatively weak electromotive force, can be modeled by coupled resistive-inductive-capacitive (RLC) circuits with voltage-dependent cap...

  15. Joint HVAC transmission EMF environmental study

    Energy Technology Data Exchange (ETDEWEB)

    Stormshak, F.; Thompson, J. (Oregon State Univ., Corvallis, OR (United States))

    1992-05-01

    This document describes the rationale, procedures, and results of a carefully controlled study conducted to establish whether chronic exposure of female (ewe) Suffolk lambs to the environment of a 500-kV 60-Hz transmission line would affect various characteristics of growth, endocrine function, and reproductive development. This experiment used identical housing and management schemes for control and line-exposed ewes, thus minimizing these factors as contributors to between-group experimental error. Further, throughout the 10-month duration of this study, changes in electric and magnetic fields, audible noise, and weather conditions were monitored continuously by a computerized system. Such measurements provided the opportunity to identify any relationship between environmental factors and biological responses. Because of reports in the literature that electric and magnetic fields alter concentrations of melatonin in laboratory animals, the primary objective of this study was to ascertain whether a similar effect occurs in lambs exposed to a 500-kV a-c line in a natural setting. In addition, onset of puberty, changes in body weight, wool growth, and behavior were monitored. To determine whether the environment of a 500-kV line caused stress in the study animals, serum levels of cortisol were measured. The study was conducted at Bonneville Power Administration's Ostrander Substation near Estacada, Oregon.

  16. Tissue microscopic changes and artifacts in multi-phase post-mortem computed tomography angiography in a hospital setting: a fatal case of systemic vasculitis.

    Science.gov (United States)

    Capuani, Caroline; Guilbeau-Frugier, Céline; Mokrane, Fatima-Zohra; Delisle, Marie-Bernadette; Marcheix, Bertrand; Rousseau, Hervé; Telmon, Norbert; Rougé, Daniel; Dedouit, Fabrice

    2014-09-01

    A 27-year-old man suddenly died in hospital of acute respiratory distress syndrome secondary to severe systemic vasculitis. Multi-phase post-mortem computed tomography angiography followed by scientific autopsy of the thoracic and abdominal cavity and histology was performed, illustrating the advantages and drawbacks of such techniques. Imaging enabled us to examine the cranium, as the family refused cerebral dissection. MPMCTA revealed absence of opacification of the left middle cerebral artery. But parenchymal findings of thoracic and abdominal organs were still difficult to interpret after both imaging and macroscopic examination during the autopsy. Microscopic examination provided the definitive diagnosis of cause of death. Analysis revealed systemic vasculitis of the lung complicated by diffuse alveolar, mediastinal, splenic and retroperitoneal lesions. We were unable to determine the type of vasculitis, whether polyarteritis nodosa or microscopic polyangiitis, because of artifactual glomerular collapse. We observed some structural changes in tissue secondary to contrast agent injection, affecting the vascular system and renal parenchyma in particular. Such artifacts must be known in order to avoid misinterpreting them as pathological findings. MPMCTA and conventional autopsy are two complementary techniques showing both their specific advantages and limits which have to be known in order to choose the appropriate technique. One limit of both techniques is the detection of microscopic findings which can only be obtained by additional histological examination. This case report underlines this fact and demonstrates that caution is required in some cases if microscopic analyses are carried out after contrast agent injection.

  17. Secured Message Transmission in Mobile AD HOC Networks through Identification and Removal of Byzantine Failures

    CERN Document Server

    Anitha, V

    2011-01-01

    The emerging need for mobile ad hoc networks and secured data transmission phase is of crucial importance depending upon the environments like military. In this paper, a new way to improve the reliability of message transmission is presented. In the open collaborative MANET environment, any node can maliciously or selfishly disrupt and deny communication of other nodes. Dynamic changing topology makes it hard to determine the adversary nodes that affect the communication in MANET. An SMT protocol provides a way to secure message transmission by dispersing the message among several paths with minimal redundancy. The multiple routes selected are known as APS -Active Path Set. This paper describes a technique for fault discovery process to identify Byzantine failures which include nodes that drop, modify, or mis-route packets in an attempt to disrupt the routing service. An adaptive probing technique detects a malicious link through binary search and according to the nodes behavior, these links are avoided in th...

  18. The impact of illness on social networks: implications for transmission and control of influenza.

    Science.gov (United States)

    Van Kerckhove, Kim; Hens, Niel; Edmunds, W John; Eames, Ken T D

    2013-12-01

    We expect social networks to change as a result of illness, but social contact data are generally collected from healthy persons. Here we quantified the impact of influenza-like illness on social mixing patterns. We analyzed the contact patterns of persons from England measured when they were symptomatic with influenza-like illness during the 2009 A/H1N1pdm influenza epidemic (2009-2010) and again 2 weeks later when they had recovered. Illness was associated with a reduction in the number of social contacts, particularly in settings outside the home, reducing the reproduction number to about one-quarter of the value it would otherwise have taken. We also observed a change in the age distribution of contacts. By comparing the expected age distribution of cases resulting from transmission by (a)symptomatic persons with incidence data, we estimated the contribution of both groups to transmission. Using this, we calculated the fraction of transmission resulting from (a)symptomatic persons, assuming equal duration of infectiousness. We estimated that 66% of transmission was attributable to persons with symptomatic disease (95% confidence interval: 0.23, 1.00). This has important implications for control: Treating symptomatic persons with antiviral agents or encouraging home isolation would be expected to have a major impact on transmission, particularly since the reproduction number for this strain was low.

  19. Lateglacial-Holocene abrupt vegetation changes at Lago Trifoglietti in Calabria, Southern Italy: The setting of ecosystems in a refugial zone

    Science.gov (United States)

    Beaulieu, Jacques-Louis de; Brugiapaglia, Elisabetta; Joannin, Sébastien; Guiter, Frédéric; Zanchetta, Giovanni; Wulf, Sabine; Peyron, Odile; Bernardo, Liliana; Didier, Julien; Stock, Agnès; Rius, Damien; Magny, Michel

    2017-02-01

    Retrospective science such as palaeoecology deeply depends on the preservation of archives in sensitive places. As an example, mountains of medium altitude from Mediterranean peninsulas have long been identified by biogeographers as refuges zones allowing the survival of European temperate taxa during the ice ages, but archives to validate this hypothesis are scarce, especially in Southern Italy. Here we present a new sequence from Lago Trifoglietti (1048 m a.s.l.) in the Calabrian Mountains, which covers the Late Glacial Interstadial (LGI, corresponding to the Bölling-Alleröd period in northern-central Europe) and the transition to the Holocene. The independent chronology based on seven radiocarbon dates is supported by the evidence of three tephra layers already identified in other regional sequences. During the LGI, besides the high diversity of non arboreal pollen grains, a great number of pollens of temperate forest trees are present or abundant (mostly deciduous oaks and fir). These assemblages suggest that the site was above but not far from the upper limit of diversified woodland stands. They confirm a local survival during the last glacial. The Younger Dryas is not marked by major changes, and oak percentages are even higher, suggesting a resilient expansion at lower altitude. Surprisingly the site remains above the timberline until an aridity crisis centered at 11,100 cal 14C yr PB, which is correlated with the Preboreal Oscillation (PBO). This event is immediately followed by the local settlement of a dense fir and beech forest around the lake. A comparison with other Italian key sequences aims at explaining the climate forcing factors that governed this original vegetation dynamic. Further investigations using additional proxies are needed for a more robust climate reconstruction.

  20. 4th International Conference on Power Transmissions

    CERN Document Server

    2013-01-01

    This books contains the Proceedings of the 4th International Conference on Power Transmissions, that was held in Sinaia, Romania from June 20 -23, 2012. Power Transmissions is a very complex and multi-disciplinary scientific field of Mechanical Engineering that covers the different types of transmissions (mechanical, hydraulic, pneumatic) as well as all the machine elements involved, such as gears, bearings, shafts, couplings and a lot more. It concerns not only their basic theory but also their design, analysis, testing, application and maintenance. The requirements set to modern power transmissions are really tough to meet: They need to be more efficient, stronger, smaller, noiseless, easier to produce and to cost less. There is a strong demand to become easier in operation and maintenance, or even automatic and in maintenance-free. Last but not least, they should be easily recycled and respect the environment. Joint efforts of specialists from both academia and industry can significantly contribute to fulf...

  1. Tremendous change of the earth surface system and tectonic setting of salt-lake formation in Yuncheng Basin since 7.1 Ma

    Institute of Scientific and Technical Information of China (English)

    WANG; Qiang

    2002-01-01

    [1]Yue Leping, Palaeomagnetic polarity boundary recorded in Chinese loess and red clay, and geological significance, Acta Geophysica Sinica (in Chinese), 1995, 38(3): 311-320.[2]Zhang Yunxiang, Cheng Danling, Xue Xiangxu et al., The genetic types of the Late Neogene red clay in the middle reaches of the Yellow River, Journal of Stratigraphy (in Chinese), 1998, 22(1): 10-15.[3]Cande, S. C., Kent, D. V., A new geomagnetic polarity time scale for the Late Cretaceous and Cenozoic, Journal of Geo-physical Research, 1992, 97(13): 917-951.[4]Cande, S. C., Kent, D. V., Revised calibration of the geomagnetic polarity timesacle for the Late Cretaceous and Cenozoic, Journal of Geophysical Research, 1995, 100(6): 93-95.[5]Sun Donghuai, Liu Tungsheng, Chen Mingyang et al., Magnetostratigraphy and climate of the red clay sequence from Chinese Loess Plateau, Science in China, Ser. D, 1997, 40: 339-343.[6]Sun Donghuai, Chen Mingyang, John, S. et al., The age of magnetostratigraphy and palaeoclimatic record for Late Ceno-zoic aeolian accumulation sequence on China Loess Plateau, Science in China (in Chinese), Ser. D, 1998, 28(1): 79-84.[7]Zhu Zhaoyu, Ding Zhongli, The Climatic and Tectonic Evolution in the Loess Plateau of China during the Quaternary (in Chinese), Beijing: Geological Publishing House, 1994, 145-154.[8]Sun Jianzhong, Zhao Jingbo et al., Quaternary of Loess Plateau of China (in Chinese), Beijing: Geological Publishing House, 1991, 89-112.[9]Yue Jun, Wen Qizhong, Analytical models for the palaeoenvironmental evolution in the Nihewan beds, Acta Geological Sinica (in Chinese), 1990, 64: 249-256.[10]Wang Sumin, Yu Yuansheng, Wu Ruijin et al., Daihai-Lake Environment and Climate Change, Hefei: China Science and Tectonology University Press, 1990, 191.[11]De Deckker, P., Ostracods of athalassic saline lakes, Hydrobiologia, 1981, 81: 131-144.[12]Anadón, P., Utrilla, R., Julia, R., Palaeoenvironmental reconstruction of a

  2. Transmission risk of human trichinellosis.

    Science.gov (United States)

    Takumi, Katsuhisa; Teunis, Peter; Fonville, Manoj; Vallee, Isabelle; Boireau, Pascal; Nöckler, Karsten; van der Giessen, Joke

    2009-02-23

    Trichinella is a food-borne parasitic zoonoses and human cases are still reported in Europe mainly due to the consumption of pig meat originating from small backyard farms. Infections originating from industrialized pig farming have not been reported for decades in Europe, due to control measures to prevent the transmission of Trichinella from wildlife by indoor housing and good management practices. Therefore, risk-based monitoring programs might replace individual carcass control in industrialized pig farming as described in EU legislation SANCO 2075/2005. Transmission of Trichinella species between wildlife and the risk that may pose to humans via consumption of contaminated pork meat has not been studied quantitatively. One pathway by which human trichinellosis can occur is the rat-pig-human route. To evaluate the transmission risk though this pathway the dose responses of rat, pig, and human were studied. Experimental T. spiralis infection was performed in rats with doses of as few as 10 parasites and the data set was analysed using a newly developed dose response model that describes larvae per gram (LPG). Experimental T. spiralis infection in pig was analysed in a similar way. Furthermore nine published outbreaks of human trichinellosis were analysed to determine the dose response in humans. The risk of human trichinellosis via the rat-pig-human transmission was simulated by the Monte Carlo method. A pair of female and male parasites representing the lowest infection pressure from the environment, led to the probability of human trichinellosis by consumption of 100g of raw pork meat equal to 5% via the studied rat-pig-human pathway. In the absence of rodent control near the farm, a low infection pressure from wildlife presents a relatively high risk of human trichinellosis via consumption of uncooked pork meat.

  3. Understanding Ebola Virus Transmission

    Directory of Open Access Journals (Sweden)

    Seth Judson

    2015-02-01

    Full Text Available An unprecedented number of Ebola virus infections among healthcare workers and patients have raised questions about our understanding of Ebola virus transmission. Here, we explore different routes of Ebola virus transmission between people, summarizing the known epidemiological and experimental data. From this data, we expose important gaps in Ebola virus research pertinent to outbreak situations. We further propose experiments and methods of data collection that will enable scientists to fill these voids in our knowledge about the transmission of Ebola virus.

  4. Chagas infection transmission control: situation of transfusional transmission in Brazil and other countries of Latin America

    OpenAIRE

    Helio Moraes-Souza

    1999-01-01

    The transmission of the transfusion-associated Chagas disease is an important mechanism of its dissemination in several Latin American countries. The transmission risk depends on five factors: prevalence of infection in blood donors, degree of serological coverage, sensibility of used tests, safety of obtained results and infection risk. The Southern Cone Iniciative set off by the Pan-American Health Organization, in 1991, is contributing to the implementation of blood law in each endemic cou...

  5. Tractor Transmissions. A Teaching Reference.

    Science.gov (United States)

    American Association for Agricultural Engineering and Vocational Agriculture, Athens, GA.

    The manual was developed as a reference for teaching students about transmissions in farm tractors. The manual is divided into five sections: (1) transmission history, (2) gears and bearings in transmission, (3) sliding-gear transmissions, (4) planetary gearing, and (5) glossary. The working principles of the sliding-gear transmission, the most…

  6. Protecting the unborn -- reducing mother-to-child transmission.

    Science.gov (United States)

    Tapper, A

    1998-02-01

    HIV is transmitted to a child during pregnancy, at birth, or through the mother's milk during infancy. Since the beginning of the HIV/AIDS epidemic, 3.8 million children are estimated to have become infected with HIV and 2.7 million have died. More than 9% acquired HIV through their HIV-positive mothers and in 1997, 1600 children were infected daily. Since many women in developing countries do not have access to clean water, it is unsafe for them to bottle feed. As such, HIV-infected women in such settings have been encouraged to breast feed their infants despite the risk of perinatal HIV transmission. The most recent research, however, indicates that 10-25% of fetal/infant HIV infections occur intrauterine, 60-75% during delivery, and 20-40% postpartum. It is estimated that breast feeding increases the risk of infection by 5-40%. These findings have led the principal administrator of the European Union's HIV/AIDS program and other health experts to recommend that children be weaned from breast feeding at 4-6 months, a change from existing breast feeding guidelines. As several trials end in the near future, important results are expected in 1998 on how to prevent perinatal HIV transmission. The ethics of involving pregnant women in Africa and Asia in clinical trials to reduce perinatal HIV transmission and vitamin A supplements and vaginal lavages are discussed.

  7. Transmission Cost Allocation Methodologies for Regional Transmission Organizations

    Energy Technology Data Exchange (ETDEWEB)

    Fink, S.; Rogers, J.; Porter, K.

    2010-07-01

    This report describes transmission cost allocation methodologies for transmission projects developed to maintain or enhance reliability, to interconnect new generators, or to access new resources and enhance competitive bulk power markets, otherwise known as economic transmission projects.

  8. The new diatom training set from the Polish Baltic coast and diatom-based transfer functions as a tool for understanding past changes in the southern Baltic coastal lakes

    Science.gov (United States)

    Lutyńska, Monika; Szpikowska, Grażyna; Woszczyk, Michał; Suchińska, Anita; Burchardt, Lubomira; Messyasz, Beata

    2014-05-01

    The transfer function method has been developed as a useful tool for reconstruction of the past environmental changes. It is based on the assumption that the modern species, which ecological requirements are known, can be used to quantitative reconstructions of the past changes. The aim of the study was to gather test sets and to build diatom-based transfer function, which can be used to reconstruct changes in the trophic state and salinity in the coastal lakes on the Polish Baltic coast. In the previous years there were several attempts made to reconstruct these parameters in lagoonal waters on the Baltic coasts in Germany, Denmark, Finland, Netherland, Sweden and Norway. But so far there is no diatom test set and transfer function was built for the Polish coastal lakes. We sample diatoms form 12 lakes located along the polish Baltic coast. At the same time we monitor the physical-chemical conditions in the lakes, which includes lake water chemical composition (chlorides, phosphorous and sulphur), pH, salinity, conductivity, temperature, dissolved oxygen. We collect samples form the lakes as well as from the Baltic Sea and we analyse the whole phytoplankton composition, however the special focus in put on diatoms. The results of the analysis show seasonal changes in the chemical and physical water properties. The diatom assemblage composition and species frequency also changed significantly. This study is a contribution to the projects: NN 306 064 640 financed by National Science Centre, Poland and Virtual Institute ICLEA (Integrated Climate and Landscape Evolution Analysis) funded by the Helmholtz Association.

  9. Transmissions in vehicles 2010

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Within the international VDI congress 'Gears in vehicles 2010' of the VDI Wissensforum GmbH (Duesseldorf, Federal Republic of Germany) between 22nd and 23rd June, 2010, in Friedrichshafen (Federal Republic of Germany), the following lectures were held: (1) 8HP70H - The moldhybrid transmission from ZF - Cjallenges and achievements (P. Gutmann); (2) GETRAG boosted range extender - A highly flexible electric powertrain for maximum CO{sub 2} reduction (S. Huepkes); (3) E-Transmission between full-hybrid and E-drive (P. Tenberge); (4) Reducing NO{sub x} and particulate emissions in electrified drivelines (R. Kuberczyk); (5) Simulation aided HEV and EV development: from the component to the whole powertrain (A. Gacometti); (6) Investigations on operating behaviour of the optimized CVT hybrid driveline (B.-R. Hoehn); (7) Customer-oriented dimensioning of electrified drivetrains (M. Eghtessad); (8) Decentralized optimal control strategy for parallel hybrid electric vehicles (A. Frenkel); (9) The new generation 6-speed automatic transmission AF40 (G. Bednarek); (10) Customized mechatronic solutions for integrated transmission control units (M. Wieczorek); (11) The optimal automatic transmission for front-transverse applications - Planetary transmissions or dual clutch transmissions? (G. Gumpoltsberger); (12) The new shift-by-wire gearshift lever for the Audi A8 - Requirements and concept (T. Guttenbergere); (13) The new shift-by-wire gearshift lever for the Audi A8 - Realization (A. Giefer); (14) Fuel-efficient transmissions of the future: Calculation of the efficiency factor for vehicle transmissions (B. Volpert); (15) HT-ACM: A new polymer generation for static and dynamic gearbox sealing solutions (E. Osen); (16) 'Energy efficiency equipped solutions by SKF' for power train applications - A contribution to CO{sub 2} - emission reduction and sustainability (T. Bobke); (17) 6-Ratio planetary shift transmission controlled by 4 external brakes, and design

  10. Watching Handball Transmissions

    DEFF Research Database (Denmark)

    Frandsen, Kirsten

    2010-01-01

    , due to the dramaturgic structure of handball transmissions, viewers consider such transmissions particularly reliable and effective sources of entertainment. The transmissions’ entertainment value derives from their specific ability to give the viewers a complex experience of feeling autonomous...... and competent when mastering the game and in relation to others. The study shows that entertainment concerns both affective involvement and identity formation, as social and cultural meaning seem to be at the root of involvement. Even though both men and women find great joy in the transmissions, their viewing...... is embedded in quite diverse patterns regarding additional media use. This points to gendered differences regarding how the entertaining experience is basically received and the qualities sought and pursued in the transmissions....

  11. Down hole transmission system

    Science.gov (United States)

    Hall, David R.; Hall, Jr., H. Tracy

    2007-07-24

    A transmission system in a downhole component comprises a data transmission element in both ends of the downhole component. Each data transmission element houses an electrically conducting coil in a MCEI circular trough. The electrically conducting coil comprises at least two generally fractional loops. In the preferred embodiment, the transmission elements are connected by an electrical conductor. Preferably, the electrical conductor is a coaxial cable. Preferably, the MCEI trough comprises ferrite. In the preferred embodiment, the fractional loops are connected by a connecting cable. In one aspect of the present invention, the connecting cable is a pair of twisted wires. In one embodiment the connecting cable is a shielded pair of twisted wires. In another aspect of the present invention, the connecting cable is a coaxial cable. The connecting cable may be disposed outside of the MCEI circular trough.

  12. Transmission of Mumps

    Science.gov (United States)

    ... Serology Publications and Resources Multimedia MMWR Articles Outbreak Articles Related Links World Health Organization Medline Plus Transmission of Mumps Language: English Español (Spanish) Recommend on Facebook Tweet Share Compartir ...

  13. Eliminating Perinatal HIV Transmission

    Centers for Disease Control (CDC) Podcasts

    2012-11-26

    In this podcast, CDC’s Dr. Steve Nesheim discusses perinatal HIV transmission, including the importance of preventing HIV among women, preconception care, and timely HIV testing of the mother. Dr. Nesheim also introduces the revised curriculum Eliminating Perinatal HIV Transmission intended for faculty of OB/GYN and pediatric residents and nurse midwifery students.  Created: 11/26/2012 by Division of HIV/AIDS Prevention.   Date Released: 11/26/2012.

  14. 77 FR 6554 - Zephyr Power Transmission, LLC; Pathfinder Power Transmission, LLC; Duke-American Transmission...

    Science.gov (United States)

    2012-02-08

    ... Energy Regulatory Commission Zephyr Power Transmission, LLC; Pathfinder Power Transmission, LLC; Duke... (Commission), 18 CFR 381.302, Zephyr Power Transmission, LLC (Zephyr), Pathfinder Power Transmission, LLC (PPT... to exercise its negotiated rate authority for Zephyr Power Transmission Project; (2) that...

  15. National transmission grid study

    Energy Technology Data Exchange (ETDEWEB)

    Abraham, Spencer [USDOE Office of the Secretary of Energy, Washington, DC (United States)

    2003-05-31

    The National Energy Policy Plan directed the U.S. Department of Energy (DOE) to conduct a study to examine the benefits of establishing a national electricity transmission grid and to identify transmission bottlenecks and measures to address them. DOE began by conducting an independent analysis of U.S. electricity markets and identifying transmission system bottlenecks using DOE’s Policy Office Electricity Modeling System (POEMS). DOE’s analysis, presented in Section 2, confirms the central role of the nation’s transmission system in lowering costs to consumers through increased trade. More importantly, DOE’s analysis also confirms the results of previous studies, which show that transmission bottlenecks and related transmission system market practices are adding hundreds of millions of dollars to consumers’ electricity bills each year. A more detailed technical overview of the use of POEMS is provided in Appendix A. DOE led an extensive, open, public input process and heard a wide range of comments and recommendations that have all been considered.1 More than 150 participants registered for three public workshops held in Detroit, MI (September 24, 2001); Atlanta, GA (September 26, 2001); and Phoenix, AZ (September 28, 2001).

  16. No change in viral set point or CD4 cell decline among antiretroviral treatment-naïve, HIV-1-infected individuals enrolled in the Danish HIV Cohort Study in 1995-2010

    DEFF Research Database (Denmark)

    Helleberg, M; Kronborg, Gitte; Larsen, C S;

    2013-01-01

    . METHODS: We included all patients registered in the Danish HIV Cohort Study, who were diagnosed in 1995-2009, had a CD4 count > 100 cells/μL at diagnosis and had at least two CD4 measurements prior to initiation of antiretroviral therapy (ART). Changes in viral set point and rate of CD4 cell decline from...... enrolment until the initiation of ART by calendar year of HIV diagnosis were analysed. Time to first CD4 count......OBJECTIVES: Recent studies have reported faster progression of HIV infection than anticipated based on results from earlier studies. The aim of the present study was to examine if the virulence of HIV-1 infection changed in the period 1995-2010 among chronically HIV-infected individuals in Denmark...

  17. Pneumothorax effects on pulmonary acoustic transmission.

    Science.gov (United States)

    Mansy, Hansen A; Balk, Robert A; Warren, William H; Royston, Thomas J; Dai, Zoujun; Peng, Ying; Sandler, Richard H

    2015-08-01

    Pneumothorax (PTX) is an abnormal accumulation of air between the lung and the chest wall. It is a relatively common and potentially life-threatening condition encountered in patients who are critically ill or have experienced trauma. Auscultatory signs of PTX include decreased breath sounds during the physical examination. The objective of this exploratory study was to investigate the changes in sound transmission in the thorax due to PTX in humans. Nineteen human subjects who underwent video-assisted thoracic surgery, during which lung collapse is a normal part of the surgery, participated in the study. After subjects were intubated and mechanically ventilated, sounds were introduced into their airways via an endotracheal tube. Sounds were then measured over the chest surface before and after lung collapse. PTX caused small changes in acoustic transmission for frequencies below 400 Hz. A larger decrease in sound transmission was observed from 400 to 600 Hz, possibly due to the stronger acoustic transmission blocking of the pleural air. At frequencies above 1 kHz, the sound waves became weaker and so did their changes with PTX. The study elucidated some of the possible mechanisms of sound propagation changes with PTX. Sound transmission measurement was able to distinguish between baseline and PTX states in this small patient group. Future studies are needed to evaluate this technique in a wider population.

  18. Force transmission in epithelial tissues.

    Science.gov (United States)

    Vasquez, Claudia G; Martin, Adam C

    2016-03-01

    In epithelial tissues, cells constantly generate and transmit forces between each other. Forces generated by the actomyosin cytoskeleton regulate tissue shape and structure and also provide signals that influence cells' decisions to divide, die, or differentiate. Forces are transmitted across epithelia because cells are mechanically linked through junctional complexes, and forces can propagate through the cell cytoplasm. Here, we review some of the molecular mechanisms responsible for force generation, with a specific focus on the actomyosin cortex and adherens junctions. We then discuss evidence for how these mechanisms promote cell shape changes and force transmission in tissues.

  19. Impacts of future deforestation and climate change on the hydrology of the Amazon Basin: a multi-model analysis with a new set of land-cover change scenarios

    Science.gov (United States)

    Guimberteau, Matthieu; Ciais, Philippe; Ducharne, Agnès; Boisier, Juan Pablo; Dutra Aguiar, Ana Paula; Biemans, Hester; De Deurwaerder, Hannes; Galbraith, David; Kruijt, Bart; Langerwisch, Fanny; Poveda, German; Rammig, Anja; Andres Rodriguez, Daniel; Tejada, Graciela; Thonicke, Kirsten; Von Randow, Celso; Von Randow, Rita C. S.; Zhang, Ke; Verbeeck, Hans

    2017-03-01

    Deforestation in Amazon is expected to decrease evapotranspiration (ET) and to increase soil moisture and river discharge under prevailing energy-limited conditions. The magnitude and sign of the response of ET to deforestation depend both on the magnitude and regional patterns of land-cover change (LCC), as well as on climate change and CO2 levels. On the one hand, elevated CO2 decreases leaf-scale transpiration, but this effect could be offset by increased foliar area density. Using three regional LCC scenarios specifically established for the Brazilian and Bolivian Amazon, we investigate the impacts of climate change and deforestation on the surface hydrology of the Amazon Basin for this century, taking 2009 as a reference. For each LCC scenario, three land surface models (LSMs), LPJmL-DGVM, INLAND-DGVM and ORCHIDEE, are forced by bias-corrected climate simulated by three general circulation models (GCMs) of the IPCC 4th Assessment Report (AR4). On average, over the Amazon Basin with no deforestation, the GCM results indicate a temperature increase of 3.3 °C by 2100 which drives up the evaporative demand, whereby precipitation increases by 8.5 %, with a large uncertainty across GCMs. In the case of no deforestation, we found that ET and runoff increase by 5.0 and 14 %, respectively. However, in south-east Amazonia, precipitation decreases by 10 % at the end of the dry season and the three LSMs produce a 6 % decrease of ET, which is less than precipitation, so that runoff decreases by 22 %. For instance, the minimum river discharge of the Rio Tapajós is reduced by 31 % in 2100. To study the additional effect of deforestation, we prescribed to the LSMs three contrasted LCC scenarios, with a forest decline going from 7 to 34 % over this century. All three scenarios partly offset the climate-induced increase of ET, and runoff increases over the entire Amazon. In the south-east, however, deforestation amplifies the decrease of ET at the end of dry season

  20. 77 FR 16435 - Transmission Relay Loadability Reliability Standard

    Science.gov (United States)

    2012-03-21

    ... presence of devices such as series capacitors, and address circuit and transformer thermal capability. 19... conditions on all applicable transmission lines and transformers. I. Background A. Relay Protection Systems 2... settings on (1) all transmission lines and transformers with low- voltage terminals operated or...

  1. Stabilizing control for power converters connected to transmission lines

    NARCIS (Netherlands)

    Zainea, Marius; Schaft, Arjan van der; Buisson, Jean

    2007-01-01

    This paper proposes a switching control strategy for the set-point stabilization of a power converter connected via a transmission line to a resistive load. The strategy employs a Lyapunov function that is directly based on energy considerations of the power converter, as well as of the transmission

  2. Monitoring Atmospheric Transmission with FLAME

    Science.gov (United States)

    Zimmer, Peter C.; McGraw, J. T.; Zirzow, D. C.; Koppa, M.; Buttler-Pena, K.

    2014-01-01

    Calibration of ground-based observations in the optical and near-infrared requires precise and accurate understanding of atmospheric transmission, at least as precise and accurate as that required for the spectral energy distributions of science targets. Traditionally this has used the Langley extrapolation method, observing targets and calibrators over a range of airmass and extrapolating to zero airmass by assuming a plane-parallel homogeneous atmosphere. The technique we present uses direct measurements of the atmosphere to derive the transmission along the line of sight to science targets at a few well-chosen wavelengths. The Facility Lidar Atmospheric Monitor of Extinction (FLAME) is a 0.5m diameter three Nd:YAG wavelength (355nm, 532nm & 1064nm) elastic backscatter lidar system. Laser pulses are transmitted into the atmosphere in the direction of the science target. Photons scattered back toward the receiver by molecules, aerosols and clouds are collected and time-gated so that the backscatter intensity is measured as a function of range to the scattering volume. The system is housed in a mobile calibration lab, which also contains auxiliary instrumentation to provide a NIST traceable calibration of the transmitted laser power and receiver efficiency. FLAME was designed to create a million photons per minute signal from the middle stratosphere, where the atmosphere is relatively calm and dominated by molecules of the well-mixed atmosphere (O2 & N2). Routine radiosonde measurements of the density at these altitudes constrain the scattering efficiency in this region and, combined with calibration of the transmitter and receiver, the only remaining unknown quantity is the two-way transmission to the stratosphere. These measurements can inform atmospheric transmission models to better understand the complex and ever-changing observatory radiative transfer environment. FLAME is currently under active development and we present some of our ongoing measurements.

  3. Moral Conflict and Change in Correctional Settings

    Science.gov (United States)

    Scharf, Peter; And Others

    1973-01-01

    This article describes a therapeutic program for inmates that attempts to stimulate moral reasoning. Based on Kohlberg's theory of moral development, the program relies heavily on group meetings designed to focus on and resolve a variety of moral issues raised by the participants. Through guided moral discussions,'' participants tend to develop…

  4. Change in basic motor abilities, quality of movement and everyday activities following intensive, goal-directed, activity-focused physiotherapy in a group setting for children with cerebral palsy

    Directory of Open Access Journals (Sweden)

    Kaale Helga K

    2010-04-01

    Full Text Available Abstract Background The effects of intensive training for children with cerebral palsy (CP remain uncertain. The aim of the study was to investigate the impact on motor function, quality of movements and everyday activities of three hours of goal-directed activity-focused physiotherapy in a group setting, five days a week for a period of three weeks. Methods A repeated measures design was applied with three baseline and two follow up assessments; immediately and three weeks after intervention. Twenty-two children with hemiplegia (n = 7, diplegia (n = 11, quadriplegia (n = 2 and ataxia (n = 2 participated, age ranging 3-9 y. All levels of Gross Motor Function Classification System (GMFCS and Manual Ability Classification System (MACS were represented. Parents and professionals participated in goal setting and training. ANOVA was used to analyse change over repeated measures. Results A main effect of time was shown in the primary outcome measure; Gross Motor Function Measure-66 (GMFM-66, mean change being 4.5 (p Conclusions Basic motor abilities and self-care improved in young children with CP after goal-directed activity-focused physiotherapy with involvement of their local environment, and their need for caregiver assistance in self-care and mobility decreased. The individualized training within a group context during a limited period of time was feasible and well-tolerated. The coherence between acquisition of basic motor abilities and quality of movement should be further examined.

  5. Frequency Dependent Losses in Transmission Cable Conductors

    DEFF Research Database (Denmark)

    Olsen, Rasmus Schmidt; Holbøll, Joachim; Guðmundsdóttir, Unnur Stella

    2011-01-01

    Denmark is taking on the exciting project of undergrounding the electricity transmission grid. In 2009 it was decided by the Danish government to underground large parts of the 400 kV and the entire 132-150 kV transmission network before the end of 2030. For ensuring network stability...... and economical gain, such severe network changes necessitate correct estimation and optimisation of load conditions in the cable grid. Both IEC and IEEE have published standards for rating transmission cables' current carrying capacity. These standards are based on assumptions of a number of parameters...... of better calculation of the AC resistance of transmission cable conductors, in particular regarding higher frequencies. In this way, also losses under harmonics can be covered. Furthermore, the model is suitable for modelling of transient attenuation in high voltage cables. The AC resistance is calculated...

  6. Transmission loss between single-mode Gaussian antennas.

    Science.gov (United States)

    Perlot, Nicolas; Rohde, Michael

    2016-08-22

    We analytically derive a set of formulas for the transmission loss in vacuum between antennas that send and receive single-mode Gaussian beams. We relate our results to standard far-field link budget parameters.

  7. Ultrahigh Transmission Optical Nanofibers

    CERN Document Server

    Hoffman, J E; Grover, J A; Solano, P; Kordell, P R; Wong-Campos, J D; Orozco, L A; Rolston, S L

    2014-01-01

    We present a procedure for reproducibly fabricating ultrahigh transmission optical nanofibers (530 nm diameter and 84 mm stretch) with single-mode transmissions of 99.95 $ \\pm$ 0.02%, which represents a loss from tapering of 2.6 $\\,\\times \\,$ 10$^{-5}$ dB/mm when normalized to the entire stretch. When controllably launching the next family of higher-order modes on a fiber with 195 mm stretch, we achieve a transmission of 97.8 $\\pm$ 2.8%, which has a loss from tapering of 5.0 $\\,\\times \\,$ 10$^{-4}$ dB/mm when normalized to the entire stretch. Our pulling and transfer procedures allow us to fabricate optical nanofibers that transmit more than 400 mW in high vacuum conditions. These results, published as parameters in our previous work, present an improvement of two orders of magnitude less loss for the fundamental mode and an increase in transmission of more than 300% for higher-order modes, when following the protocols detailed in this paper. We extract from the transmission during the pull, the only reported...

  8. Can the BestGrid Process Improve Stakeholder Involvement in Electricity Transmission Projects?

    Directory of Open Access Journals (Sweden)

    Nadejda Komendantova

    2015-08-01

    Full Text Available The European Union has set ambitious targets for deployment of renewable energy sources to reach goals of climate change mitigation and energy security policies. However, the current state of electricity transmission infrastructure is a major bottleneck for further scaling up of renewable energy in the EU. Several thousands of kilometers of new lines have to be constructed and upgraded to accommodate growing volumes of intermittent renewable electricity. In many countries, construction of electricity transmission projects has been delayed for several years due to concerns of local stakeholders. The innovative BESTGRID approach, reported here, brings together transmission system operators (TSOs and non-governmental organizations (NGOs to discuss and understand the nature of stakeholder concerns. This paper has three objectives: (1 to understand stakeholder concerns about the deployment of electricity transmission grids in four pilot projects according to five guiding principles: need, transparency, engagement, environment, and impacts on human health as well as benefits; (2 to understand how these principles can be addressed to provide a basis for better decision-making outcomes; and (3 to evaluate the BESTGRID process based on feedback received from stakeholders and the level of participation achieved according to the ladder of Arnstein. This paper goes beyond a discussion of “measures to mitigate opposition” to understand how dialogue between TSOs and the public—represented mainly by NGOs and policy-makers—might lead to a better decision-making process and more sustainable electricity transmission infrastructure deployment.

  9. Supplementary magnetic tests for railway wheel sets

    Directory of Open Access Journals (Sweden)

    Zbigniew Hilary ŻUREK

    2008-01-01

    Full Text Available During manufacturing process the wheel set is subjected to many different flaw detection methods; however, these methods are not sufficient while the wheel set is in service. The paper presents an example of monitoring of magnetic parameters changes of wheel set rolling surface (changes result from material degradation due to materialfatigue.

  10. Plasmon cross transmission

    Energy Technology Data Exchange (ETDEWEB)

    Dobrzynski, Leonard; Akjouj, Abdellatif; Li, Changsheng, E-mail: Abdellatif.Akjouj@univ-lille1.fr [Centre National de la Recherche Scientifique, Universite Lille Nord de France, Lille1, Institut d' Electronique, de Microelectronique et de Nanotechnologie, Unite de Physique, Batiment P5, 59655 Villeneuve d' Ascq Cedex (France)

    2011-09-14

    Plasmon cross transmission avoids the frontal collision between two plasmons traveling in opposite directions along a guide. The guide is made out of equidistant identical metal dots. Thanks to two resonator dots, the plasmon frontal impact is avoided by transmission of the two plasmons from the input guide to an output one. The resonator and guide dots are identical in size and metal composition. The dipole-dipole interactions are restricted to first nearest neighbors. A convenient metal doping is assumed to compensate exactly all attenuations. The parameters are the nearest neighbor distances between the dots. These distances are rescaled to the chain nearest neighbor distance d. The system has two symmetry mirror planes. This simple model enables us to obtain two analytic tuning relations for the plasmon cross transmission. The intensities of the transmitted signals versus kd, where k is the plasmon propagation vector, are also given. (paper)

  11. Aerosol Transmission of Filoviruses

    Directory of Open Access Journals (Sweden)

    Berhanu Mekibib

    2016-05-01

    Full Text Available Filoviruses have become a worldwide public health concern because of their potential for introductions into non-endemic countries through international travel and the international transport of infected animals or animal products. Since it was first identified in 1976, in the Democratic Republic of Congo (formerly Zaire and Sudan, the 2013–2015 western African Ebola virus disease (EVD outbreak is the largest, both by number of cases and geographical extension, and deadliest, recorded so far in medical history. The source of ebolaviruses for human index case(s in most outbreaks is presumptively associated with handling of bush meat or contact with fruit bats. Transmission among humans occurs easily when a person comes in contact with contaminated body fluids of patients, but our understanding of other transmission routes is still fragmentary. This review deals with the controversial issue of aerosol transmission of filoviruses.

  12. Principal Components Analysis of Triaxial Vibration Data From Helicopter Transmissions

    Science.gov (United States)

    Tumer, Irem Y.; Huff, Edward M.

    2001-01-01

    Research on the nature of the vibration data collected from helicopter transmissions during flight experiments has led to several crucial observations believed to be responsible for the high rates of false alarms and missed detections in aircraft vibration monitoring systems. This work focuses on one such finding, namely, the need to consider additional sources of information about system vibrations. In this light, helicopter transmission vibration data, collected using triaxial accelerometers, were explored in three different directions, analyzed for content, and then combined using Principal Components Analysis (PCA) to analyze changes in directionality. In this paper, the PCA transformation is applied to 176 test conditions/data sets collected from an OH58C helicopter to derive the overall experiment-wide covariance matrix and its principal eigenvectors. The experiment-wide eigenvectors. are then projected onto the individual test conditions to evaluate changes and similarities in their directionality based on the various experimental factors. The paper will present the foundations of the proposed approach, addressing the question of whether experiment-wide eigenvectors accurately model the vibration modes in individual test conditions. The results will further determine the value of using directionality and triaxial accelerometers for vibration monitoring and anomaly detection.

  13. Transmission grid security

    CERN Document Server

    Haarla, Liisa; Hirvonen, Ritva; Labeau, Pierre-Etienne

    2011-01-01

    In response to the growing importance of power system security and reliability, ""Transmission Grid Security"" proposes a systematic and probabilistic approach for transmission grid security analysis. The analysis presented uses probabilistic safety assessment (PSA) and takes into account the power system dynamics after severe faults. In the method shown in this book the power system states (stable, not stable, system breakdown, etc.) are connected with the substation reliability model. In this way it is possible to: estimate the system-wide consequences of grid faults; identify a chain of eve

  14. Exoplanet Transmission Spectroscopy using KMOS

    CERN Document Server

    Parviainen, Hannu; Thatte, Niranjan; Barstow, Joanna K; Evans, Thomas M; Gibson, Neale

    2015-01-01

    KMOS (K-Band Multi Object Spectrograph) is a novel integral field spectrograph installed in the VLT's ANTU unit. The instrument offers an ability to observe 24 2.8"$\\times$2.8" sub-fields positionable within a 7.2' patrol field, each sub-field producing a spectrum with a 14$\\times$14-pixel spatial resolution. The main science drivers for KMOS are the study of galaxies, star formation, and molecular clouds, but its ability to simultaneously measure spectra of multiple stars makes KMOS an interesting instrument for exoplanet atmosphere characterization via transmission spectroscopy. We set to test whether transmission spectroscopy is practical with KMOS, and what are the conditions required to achieve the photometric precision needed, based on observations of a partial transit of WASP-19b, and full transits of GJ 1214b and HD 209458b. Our analysis uses the simultaneously observed comparison stars to reduce the effects from instrumental and atmospheric sources, and Gaussian processes to model the residual system...

  15. Neutron transmission and capture of 241Am

    Directory of Open Access Journals (Sweden)

    Sage C.

    2013-03-01

    Full Text Available A set of neutron transmission and capture experiments based on the Time Of Flight (TOF technique, were performed in order to determine the 241Am capture cross section in the energy range from 0.01 eV to 1 keV. The GELINA facility of the Institute for Reference Materials and Measurements (IRMM served as the neutron source. A pair of C6D6 liquid scintillators was used to register the prompt gamma rays emerging from the americium sample, while a Li-glass detector was used in the transmission setup. Results from the capture and transmission data acquired are consistent with each other, but appear to be inconsistent with the evaluated data files. Resonance parameters have been derived for the data up to the energy of 100 eV.

  16. Dilemmas of Cultural Transmission

    Science.gov (United States)

    Kováts-Németh, Mária

    2016-01-01

    The fundamental problem of the 21st century is that in the modern civilization "the transmission of values is not stable." There is nothing, except for the natural sense of justice and some legal traditions, which would exercise selective power on social behavior. At a critical time in 1949 Albert Szent-Györgyi drew the attention to the…

  17. Facsimile Transmission Standards

    Science.gov (United States)

    1993-10-01

    transmettre les cartes tactiques et les compte rendu de situation. La presente note technique expose les 6lements nec~ssaires A la transmission de t~l6copies...Group MI machines introduced digital scanning techniques in which the single photoelectric cell was replaced with a Charged Coupled Device (CCD) array

  18. Intergenerational Transmission of Volunteering

    NARCIS (Netherlands)

    Bekkers, René

    2007-01-01

    In this article, I investigate the strength of intergenerational transmission of volunteering for non-profit associations in The Netherlands. Data from the Family Survey of the Dutch Population 2000 reveal that there are significant relations between current volunteering and parental volunteering in

  19. Laser power transmission

    Science.gov (United States)

    Conway, Edmund J.

    1992-01-01

    An overview of previous studies related to laser power transmission is presented. Particular attention is given to the use of solar pumped lasers for space power applications. Three general laser mechanisms are addressed: photodissociation lasing driven by sunlight, photoexcitation lasing driven directly by sunlight, and photoexcitation lasing driven by thermal radiation.

  20. [Effects of transmission counts on image quality during simultaneous emission/transmission scan].

    Science.gov (United States)

    Inoue, Kazumasa; Oda, Keiichi; Fukushi, Masahiro

    2006-06-20

    We compared the pre-injection transmission scan with the simultaneous emission/transmission scan (SET) using a body phantom in positron emission tomography (PET) to study the factors affecting emission (EMIS) images with different transmission (TRAN) data. The results showed that total count, region, scan method, and EMIS component influenced the bias and noise statistics. This influence was further passed on to the EMIS data and affected the reconstructed image. However, the result of fixing EMIS scan time at 10 minutes was that the noise statistics of EMIS had a greater effect on image quality than TRAN. The optimal scan counts of SET in this study were 20 Mcounts, with a scan time of about 10 minutes (85.5 MBq, (68)Ge-(68)Ga radioactivity). In clinical use, optimal collection count differs, as radiation TRAN quantity depends on the size of the subject, even with fixed radioactivity of (68)Ge-(68)Ga.

  1. Fuzzy sets, rough sets, multisets and clustering

    CERN Document Server

    Dahlbom, Anders; Narukawa, Yasuo

    2017-01-01

    This book is dedicated to Prof. Sadaaki Miyamoto and presents cutting-edge papers in some of the areas in which he contributed. Bringing together contributions by leading researchers in the field, it concretely addresses clustering, multisets, rough sets and fuzzy sets, as well as their applications in areas such as decision-making. The book is divided in four parts, the first of which focuses on clustering and classification. The second part puts the spotlight on multisets, bags, fuzzy bags and other fuzzy extensions, while the third deals with rough sets. Rounding out the coverage, the last part explores fuzzy sets and decision-making.

  2. The Partial Fuzzy Set

    OpenAIRE

    Dr.Pranita Goswami

    2011-01-01

    The Partial Fuzzy Set is a portion of the Fuzzy Set which is again a Fuzzy Set. In the Partial Fuzzy Set the baseline is shifted from 0 to 1 to any of its α cuts . In this paper we have fuzzified a portion of the Fuzzy Set by transformation

  3. Transmission network expansion planning under deliberate outages

    Energy Technology Data Exchange (ETDEWEB)

    Alguacil, Natalia; Carrion, Miguel; Arroyo, Jose Manuel [E.T.S. de Ingenieros Industriales, Universidad de Castilla - La Mancha, Campus Universitario s/n, 13071 Ciudad Real (Spain)

    2009-10-15

    The reasons why the transmission network is a potentially attractive target for deliberate outages are twofold: (i) its crucial importance as a critical infrastructure for the society welfare, and (ii) its high level of vulnerability due to the current operation close to its static and dynamic limits. This new context where destructive agents come into play has been recognized by several agencies in Europe and North America, and various initiatives have been launched worldwide in order to assess and mitigate the vulnerability of transmission. Within this framework, this paper proposes the reinforcement and expansion of the transmission network as a way of mitigating the impact of increasingly plausible deliberate outages. The network planner selects the new lines to be built accounting not only for economic issues, as traditionally done, but also for the vulnerability of the transmission network against a set of credible intentional outages. The resulting vulnerability- and economic-constrained transmission expansion planning problem is formulated as a mixed-integer linear program. A number of case studies numerically illustrate the tradeoff between economic- and vulnerability-related issues and its impact on the expansion plans. In addition, we compare the results with those achieved by a traditional expansion planning model based on cost minimization. (author)

  4. Heterogeneities in the infection process drive ranavirus transmission.

    Science.gov (United States)

    Brunner, Jesse L; Beaty, Lynne; Guitard, Alexandra; Russell, Deanna

    2017-02-01

    Transmission is central to our understanding and efforts to control the spread of infectious diseases. Because transmission generally requires close contact, host movements and behaviors can shape transmission dynamics: random and complete mixing leads to the classic density-dependent model, but if hosts primarily interact locally (e.g., aggregate) or within groups, transmission may saturate. Manipulating host behavior may thus change both the rate and functional form of transmission. We used the ranavirus-wood frog (Lithobates sylvaticus) tadpole system to test whether transmission rates reflect contacts, and whether the functional form of transmission can be influenced by the distribution of food in mesocosms (widely dispersed, promoting random movement and mixing vs. a central pile, promoting aggregations). Contact rates increased with density, as expected, but transmission rapidly saturated. Observed rates of transmission were not explained by observed contact rates or the density-dependent model, but instead transmission in both treatments followed models allowing for heterogeneities in the transmission process. We argue that contacts were not generally limiting, but instead that our results are better explained by heterogeneities in host susceptibility. Moreover, manipulating host behavior to manage the spread of infectious disease may prove difficult to implement.

  5. Border Malaria Associated with Multidrug Resistance on Thailand-Myanmar and Thailand-Cambodia Borders: Transmission Dynamic, Vulnerability, and Surveillance

    Directory of Open Access Journals (Sweden)

    Adisak Bhumiratana

    2013-01-01

    Full Text Available This systematic review elaborates the concepts and impacts of border malaria, particularly on the emergence and spread of Plasmodium falciparum and Plasmodium vivax multidrug resistance (MDR malaria on Thailand-Myanmar and Thailand-Cambodia borders. Border malaria encompasses any complex epidemiological settings of forest-related and forest fringe-related malaria, both regularly occurring in certain transmission areas and manifesting a trend of increased incidence in transmission prone areas along these borders, as the result of interconnections of human settlements and movement activities, cross-border population migrations, ecological changes, vector population dynamics, and multidrug resistance. For regional and global perspectives, this review analyzes and synthesizes the rationales pertaining to transmission dynamics and the vulnerabilities of border malaria that constrain surveillance and control of the world’s most MDR falciparum and vivax malaria on these chaotic borders.

  6. Regional transmission subsystem planning

    Energy Technology Data Exchange (ETDEWEB)

    Costa Bortoni, Edson da [Quadrante Softwares Especializados Ltda., Itajuba, MG (Brazil); Bajay, Sergio Valdir; Barros Correia, Paulo de [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica; Santos, Afonso Henriques Moreira; Haddad, Jamil [Escola Federal de Engenharia de Itajuba, MG (Brazil)

    1994-12-31

    This work presents an approach for the planning of transmission systems by employing mixed--integer linear programming to obtain a cost and operating characteristics optimized system. The voltage loop equations are written in a modified form, so that, at the end of the analysis, the model behaves as a DC power flow, with the help of the two Kirchhoff`s laws, exempting the need of interaction with an external power flow program for analysis of the line loading. The model considers the occurrence of contingencies, so that the final result is a network robust to the most severe contingencies. This whole technique is adapted to the regional electric power transmission subsystems. (author) 9 refs., 4 figs.

  7. Transmission planning in a deregulated environment

    DEFF Research Database (Denmark)

    Xu, Zhao

    2006-01-01

    The worldwide trend for the deregulation of the electricity generation and transmission industries has led to dramatic changes in system operation and planning procedures. The optimum approach to transmission-expansion planning in a deregulated environment is an open problem especially when...... the responsibilities of the organisations carrying out the planning work need to be addressed. To date there is a consensus that the system operator and network manager perform the expansion planning work in a centralised way. However, with an increasing input from the electricity market, the objectives, constraints...... electricity market grid are performed. In addition, the proposed method is compared with a traditional planning method to further verify its effectiveness....

  8. Electromagnetic analysis using transmission line variables

    CERN Document Server

    Weiner, Maurice

    2010-01-01

    This book employs a relatively new method for solving electromagnetic problems, one which makes use of a transmission line matrix (TLM). The propagation space is imagined to be filled with this matrix. The propagating fields and physical properties are then mapped onto the matrix. Mathematically, the procedures are identical with the traditional numerical methods; however, the interpretation and physical appeal of the transmission line matrix are far superior. Any change in the matrix has an immediate physical significance. What is also very important is that the matrix becomes a launching pad

  9. NB Power Transmission system

    Energy Technology Data Exchange (ETDEWEB)

    Williamson, J. [NB Power Transmission, Fredericton, NB (Canada)

    2006-07-01

    The NB Power Transmission System operates 6700 km of transmission lines having voltages of 69 kV, 138 kV, 230 kV, and 345 kV. The history of lightning protection on this transmission system was presented. Lightning protection with shield wires has been applied selectively on the 69 kV and 138 kV lines and has been applied to all lines in the 230 kV and 345 kV range. Beginning in 2000, line arresters were installed on selected 69 kV and 138 kV lines. It was noted that although overhead shield wires are commonly installed to capture lightning strikes and shield the conductors, problems can occur if the electrical flashover of insulators result in a line to ground fault. Good grounding is needed to ensure that lightning enters the ground from the tower. The new approach is to install line arresters on structures without overhead shield wires. Line arresters are surge arresters applied in parallel with the insulator string. This new line arrester technology was tested by installing nearly 1200 arresters in the Saint John area. This paper described the reasons for choosing line arresters over shield wires and presented the methods of installation. The problems and failure rates of the installed line arresters were presented along with solutions, including solutions to protect lines against lightning in areas with heavy icing. Recommendations for future research into the use, application and development of line arresters were also presented. tabs., figs.

  10. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Within the last decade we have experienced deregulation of several industries, such as airlines, telecommunications and the electric utility industry, the last-mentioned being the focus of this work. Both the telecommunications and the electricity sector depend on network facilities, some of which are still considered as natural monopolies. In these industries, open network access is regarded as crucial in order to achieve the gains from increased competition, and transmission tariffs are important in implementing this. Based on the Energy Act that was introduced in 1991, Norway was among the first countries to restructure its electricity sector. On the supply side there are a large number of competing firms, almost exclusively hydro plants, with a combined capacity of about 23000 MW, producing 105-125 TWh per year, depending on the availability of water. Hydro plants are characterized by low variable costs of operation, however since water may be stored in dams, water has an opportunity cost, generally known as the water value, which is the shadow price of water when solving the generator's inter temporal profit maximization problem. Water values are the main factor of the producers' short run marginal cost. Total consumption amounts to 112-117 TWh a year, and consumers, even households, may choose their electricity supplier independent of the local distributor to which the customer is connected. In fact, approximately 10% of the households have actually changed supplier. The web-site www.konkurransetilsynet.no indicates available contracts, and www.dinside.no provides an ''energy-calculator'' where one can check whether it is profitable to switch supplier. If a customer buys energy from a remote supplier, the local distributor only provides transportation facilities for the energy and is compensated accordingly. Transmission and distribution have remained monopolized and regulated by the Norwegian Water Resources and Energy

  11. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Within the last decade we have experienced deregulation of several industries, such as airlines, telecommunications and the electric utility industry, the last-mentioned being the focus of this work. Both the telecommunications and the electricity sector depend on network facilities, some of which are still considered as natural monopolies. In these industries, open network access is regarded as crucial in order to achieve the gains from increased competition, and transmission tariffs are important in implementing this. Based on the Energy Act that was introduced in 1991, Norway was among the first countries to restructure its electricity sector. On the supply side there are a large number of competing firms, almost exclusively hydro plants, with a combined capacity of about 23000 MW, producing 105-125 TWh per year, depending on the availability of water. Hydro plants are characterized by low variable costs of operation, however since water may be stored in dams, water has an opportunity cost, generally known as the water value, which is the shadow price of water when solving the generator's inter temporal profit maximization problem. Water values are the main factor of the producers' short run marginal cost. Total consumption amounts to 112-117 TWh a year, and consumers, even households, may choose their electricity supplier independent of the local distributor to which the customer is connected. In fact, approximately 10% of the households have actually changed supplier. The web-site www.konkurransetilsynet.no indicates available contracts, and www.dinside.no provides an ''energy-calculator'' where one can check whether it is profitable to switch supplier. If a customer buys energy from a remote supplier, the local distributor only provides transportation facilities for the energy and is compensated accordingly. Transmission and distribution have remained monopolized and regulated by the Norwegian Water Resources and Energy

  12. Multiaspect Soft Sets

    Directory of Open Access Journals (Sweden)

    Nor Hashimah Sulaiman

    2013-01-01

    Full Text Available We introduce a novel concept of multiaspect soft set which is an extension of the ordinary soft set by Molodtsov. Some basic concepts, operations, and properties of the multiaspect soft sets are studied. We also define a mapping on multiaspect soft classes and investigate several properties related to the images and preimages of multiaspect soft sets.

  13. Social Set Analysis

    DEFF Research Database (Denmark)

    Vatrapu, Ravi; Mukkamala, Raghava Rao; Hussain, Abid

    2016-01-01

    this limitation, based on the sociology of associations and the mathematics of set theory, this paper presents a new approach to big data analytics called social set analysis. Social set analysis consists of a generative framework for the philosophies of computational social science, theory of social data......, conceptual and formal models of social data, and an analytical framework for combining big social data sets with organizational and societal data sets. Three empirical studies of big social data are presented to illustrate and demonstrate social set analysis in terms of fuzzy set-theoretical sentiment...... analysis, crisp set-theoretical interaction analysis, and event-studies-oriented set-theoretical visualizations. Implications for big data analytics, current limitations of the set-theoretical approach, and future directions are outlined....

  14. Improving the Energy Market: Algorithms, Market Implications, and Transmission Switching

    Science.gov (United States)

    Lipka, Paula Ann

    corresponding to the accuracy and AC-feasiblity of the solution. This linearization was tested on the IEEE and Polish systems, which range from 14 to 3375 buses and 20 to 4161 transmission lines. It had an accuracy of 0.5% or less for all but the 30-bus system. It also solved in linear time with CPLEX, while the non-linear version solved in O(n1.11) to O(n1.39). The sequential linearization is slower than the nonlinear formulation for smaller problems, but faster for larger problems, and its linear computational time means it would continue solving faster for larger problems. A major consideration to implementing algorithms to solve the optimal generator dispatch is ensuring that the resulting prices from the algorithm will support the market. Since the sequential linearization is linear, it is convex, its marginal values are well-defined, and there is no duality gap. The prices and settlements obtained from the sequential linearization therefore can be used to run a market. This market will include extra prices and settlements for reactive power and voltage, compared to the present-day market, which is based on real power. An advantage of this is that there is a very clear pool that can be used for reactive power/voltage support payments, while presently there is not a clear pool to take them out of. This method also reveals how valuable reactive power and voltage are at different locations, which can enable better planning of reactive resource construction. Transmission switching increases the feasible region of the generator dispatch, which means there may be a better solution than without transmission switching. Power flows on transmission lines are not directly controllable; rather, the power flows according to how it is injected and the physical characteristics of the lines. Changing the network topology changes the physical characteristics, which changes the flows. This means that sets of generator dispatch that may have previously been infeasible due to the flow

  15. Transmission eigenvalues for elliptic operators

    CERN Document Server

    Hitrik, Michael; Ola, Petri; Päivärinta, Lassi

    2010-01-01

    A reduction of the transmission eigenvalue problem for multiplicative sign-definite perturbations of elliptic operators with constant coefficients to an eigenvalue problem for a non-selfadjoint compact operator is given. Sufficient conditions for the existence of transmission eigenvalues and completeness of generalized eigenstates for the transmission eigenvalue problem are derived. In the trace class case, the generic existence of transmission eigenvalues is established.

  16. Cultural transmission of civic attitudes

    OpenAIRE

    Miles-Touya, Daniel; Rossi, Máximo

    2016-01-01

    In this empirical paper we attempt to measure the separate influence on civic engagement of educational attainment and cultural transmission of civic attitudes. Unlike most of the previous empirical works on this issue, we are able to approximate the cultural transmission of civic attitudes. We observe that civic returns to education are overstated when the transmission of civic attitudes is ignored. Moreover, the transmission of civic attitudes significantly enhances civic involvement and re...

  17. Optimizing Transmission Line Matching Circuits

    OpenAIRE

    Novak, S.

    1996-01-01

    When designing transmission line matching circuits, there exist often overlooked, additional, not much used, degree of choice in the selection of the transmission line impedance. In this work are presented results of CAD analysis for the two element transmission line matching networks, demonstrating that selecting matching circuits transmission lines with higher impedance, than usually used 50 or 75 ohms, can in most cases substantially decrease the physical dimension of the final matching ci...

  18. Transmission of asymmetric coupling double-ring resonator

    Science.gov (United States)

    Zhao, C. Y.; Tan, W. H.

    2015-02-01

    Based on the asymmetry between waveguide and double ring, the transmission and phase characteristics of coupled double-ring resonators are analyzed systemically. It is shown that the initial detuning determines the shape of transmission spectrum. The transmission spectrum of all-optical analog to electromagnetic inducted transparency (EIT) is controlled by tuning the asymmetric coupled parameter and loss. With the increasing of asymmetric coupled parameter, the transmission spectrum changes from EIT-like profile to Lorenz profile. The EIT-like transmission spectrum results from the interference between two Lorenz profiles. With the increasing of the loss, the transmission spectrum full frequency width at half-maximum broadens and its peak declines. The detuning and loss also make significant influences on the phase profile.

  19. Sets in Coq, Coq in Sets

    Directory of Open Access Journals (Sweden)

    Bruno Barras

    2010-01-01

    Full Text Available This work is about formalizing models of various type theories of the Calculus of Constructions family. Here we focus on set theoretical models. The long-term goal is to build a formal set theoretical model of the Calculus of Inductive Constructions, so we can be sure that Coq is consistent with the language used by most mathematicians.One aspect of this work is to axiomatize several set theories: ZF possibly with inaccessible cardinals, and HF, the theory of hereditarily finite sets. On top of these theories we have developped a piece of the usual set theoretical construction of functions, ordinals and fixpoint theory. We then proved sound several models of the Calculus of Constructions, its extension with an infinite hierarchy of universes, and its extension with the inductive type of natural numbers where recursion follows the type-based termination approach.The other aspect is to try and discharge (most of these assumptions. The goal here is rather to compare the theoretical strengths of all these formalisms. As already noticed by Werner, the replacement axiom of ZF in its general form seems to require a type-theoretical axiom of choice (TTAC.

  20. Modelling lightning caused transmission line outages in Alberta

    Energy Technology Data Exchange (ETDEWEB)

    Wu, M.; Shen, S.S.P. [Alberta Univ., Edmonton, AB (Canada). Dept. of Mathematical and Statistical Sciences; Koval, D.O. [Alberta Univ., Edmonton, AB (Canada). Dept. of Electrical Engineering

    2005-07-01

    The characteristics of lightning and the relationship between lightning and transmission line outages is not fully understood by utility planners. This study used 20 year data sets of lightning events to investigate the spatial and temporal patterns of lightning in Alberta. Studies of geographical and temporal characteristics of lightning caused transmission line outages for several voltage level transmission lines were also examined. A lasso regression variable selection procedure and Cp criterion were used to model the duration of the lightning-caused transmission line outages as a function of weather and lightning patterns. The province was divided into 110 by 110 grids, and lightning variables were calculated for each cell. All the lightning variables for each cell were then averaged based on their areas. The overall cloud-ground lightning flashes 20-year mean frequency and the physical locations of power transmission lines were then plotted. Estimated probability density functions of the duration of lightning caused transmission line outages were classified by their voltage levels. The study showed that the characteristics of the lightning caused outages were different for different voltage levels of the transmission lines. Results suggested that the findings will have a significant impact on the accuracy of reliability methodologies that use the average duration of transmission line outages in their calculations. It was concluded that the new methodology can be applied to any transmission line system operating in a unique geographical environmental area. 11 refs., 3 tabs., 5 figs.

  1. On the transmission of terahertz radiation through silicon-based structures

    Energy Technology Data Exchange (ETDEWEB)

    Persano, Anna, E-mail: anna.persano@le.imm.cnr.it; Francioso, Luca; Cola, Adriano [Institute for Microelectronics and Microsystems–Unit of Lecce, National Council of Research (IMM-CNR), Via Monteroni, Lecce 73100 (Italy); Torres, Jérémie; Nouvel, Philippe; Varani, Luca [Institut d' Electronique du Sud, CNRS UMR 5214, TeraLab, University Montpellier 2, Montpellier (France); Korotyeyev, Vadym V.; Lyaschuk, Yu M. [Department of Theoretical Physics, Institute of Semiconductor Physics, Kiev 03028 (Ukraine)

    2014-07-28

    We report on the transmission of a terahertz (THz) radiation through prototype structures based on a p-type silicon substrate. In particular, the bare substrate and progressively more complicated multilayer structures were investigated, allowing to address the effect on the transmission of different factors, such as the orientation of interdigitated contacts with respect to the polarized beam, the temperature, and the current flowing through a conductive SnO{sub 2} nanorods layer. A suitable experimental set-up was developed for the direct spectral measurement of transmission in the range of 0.75–1.1 THz at room and low temperatures. A simple Drude-Lorentz model was formulated, finding a quantitative agreement with the experimental transmission spectrum of the bare substrate at room temperature. For the multilayer structures, the spectra variations observed with temperature are well accounted by the corresponding change of the mobility of holes in the silicon p-type substrate. The influence of the contact orientation is consistent with that of a polarizing metallic grating. Finally, Joule heating effects are observed in the spectra performed as a function of the current flowing through the SnO{sub 2} nanorods layer. The experimental results shown here, together with their theoretical interpretation, provide insights for the development of devices fabricated on conductive substrates aimed to absorb/modulate radiation in the THz range.

  2. Degradation of rural and urban great tit song: testing transmission efficiency.

    Directory of Open Access Journals (Sweden)

    Emily J Mockford

    Full Text Available Acoustic signals play a fundamental role in avian territory defence and mate attraction. Several studies have now shown that spectral properties of bird song differ between urban and rural environments. Previously this has been attributed to competition for acoustic space as a result of low-frequency noise present in cities. However, the physical structure of urban areas may have a contributory effect. Here we investigate the sound degradation properties of woodland and city environments using both urban and rural great tit song. We show that although urban surroundings caused significantly less degradation to both songs, the transmission efficiency of rural song compared to urban song was significantly lower in the city. While differences between the two songs in woodland were generally minimal, some measures of the transmission efficiency of rural song were significantly lower than those of urban song, suggesting additional benefits to singing rural songs in this setting. In an attempt to create artificial urban song, we mimicked the increase in minimum frequency found several times previously in urban song. However, this did not replicate the same transmission properties as true urban song, suggesting changes in other song characteristics, such as temporal adjustments, are needed to further increase transmission of an avian signal in the city. We suggest that the structure of the acoustic environment, in addition to the background noise, plays an important role in signal adaptation.

  3. Sets resilient to erosion

    CERN Document Server

    Pegden, Wesley

    2011-01-01

    The erosion of a set in Euclidean space by a radius r>0 is the subset of X consisting of points at distance >/-r from the complement of X. A set is resilient to erosion if it is similar to its erosion by some positive radius. We give a somewhat surprising characterization of resilient sets, consisting in one part of simple geometric constraints on convex resilient sets, and, in another, a correspondence between nonconvex resilient sets and scale-invariant (e.g., 'exact fractal') sets.

  4. Invariant sets for Windows

    CERN Document Server

    Morozov, Albert D; Dragunov, Timothy N; Malysheva, Olga V

    1999-01-01

    This book deals with the visualization and exploration of invariant sets (fractals, strange attractors, resonance structures, patterns etc.) for various kinds of nonlinear dynamical systems. The authors have created a special Windows 95 application called WInSet, which allows one to visualize the invariant sets. A WInSet installation disk is enclosed with the book.The book consists of two parts. Part I contains a description of WInSet and a list of the built-in invariant sets which can be plotted using the program. This part is intended for a wide audience with interests ranging from dynamical

  5. Dynamically prioritized progressive transmission

    Science.gov (United States)

    Blanford, Ronald

    1992-04-01

    Retrieval of image data from a centralized database may be subject to bandwidth limitations, whether due to a low-bandwidth communications link or to contention from simultaneous accesses over a high-bandwidth link. Progressive transmission can alleviate this problem by encoding image data so that any prefix of the data stream approximates the complete image at a coarse level of resolution. The longer the prefix, the finer the resolution. In many cases, as little at 1 percent of the image data may be sufficient to decide whether to discard the image, to permit the retrieval to continue, or to restrict retrieval to a subsection of the image. Our approach treats resolution not as a fixed attribute of the image, but rather as a resource which may be allocated to portions of the image at the direction of a user-specified priority function. The default priority function minimizes error by allocating more resolution to regions of high variance. The user may also point to regions of interest requesting priority transmission. More advanced target recognition strategies may be incorporated at the user's discretion. Multispectral imagery is supported. The user engineering implications are profounded. There is immediate response to a query that might otherwise take minutes to complete. The data is transmitted in small increments so that no single user dominates the communications bandwidth. The user-directed improvement means that bandwidth is focused on interesting information. The user may continue working with the first coarse approximations while further image data is still arriving. The algorithm has been implemented in C on Sun, Silicon Graphics, and NeXT workstations, and in Lisp on a Symbolics. Transmission speeds reach as high as 60,000 baud using a Sparc or 68040 processor when storing data to memory; somewhat less if also updating a graphical display. The memory requirements are roughly five bytes per image pixel. Both computational and memory costs may be reduced

  6. Research and Transmission

    Directory of Open Access Journals (Sweden)

    Denise Pumain

    2001-01-01

    Full Text Available The present situation provides a challenge for us to reconsider the necessary link between science and pedagogy, between research and the transmission of knowledge. The Ministry of National education has just inaugurated a broad consultation of teachers on every level with a view to modernising and giving coherence to the programs of secondary education. Armand Frémont will head the group of experts responsible for history and geography. Is this a coincidence? The changeover in the jury for t...

  7. Conventional transmission electron microscopy.

    Science.gov (United States)

    Winey, Mark; Meehl, Janet B; O'Toole, Eileen T; Giddings, Thomas H

    2014-02-01

    Researchers have used transmission electron microscopy (TEM) to make contributions to cell biology for well over 50 years, and TEM continues to be an important technology in our field. We briefly present for the neophyte the components of a TEM-based study, beginning with sample preparation through imaging of the samples. We point out the limitations of TEM and issues to be considered during experimental design. Advanced electron microscopy techniques are listed as well. Finally, we point potential new users of TEM to resources to help launch their project.

  8. The Effect of Early Clinical Exposure Program on Attitude Change of Undergraduate Medical Students toward their preparation for Attending Clinical Setting in Internal Medicine, Surgery and Pediatrics Wards during 2013-2014

    Directory of Open Access Journals (Sweden)

    M.A. Seifrabei

    2016-01-01

    Full Text Available Introduction & Objective: This study was conducted to evaluate the effect of early clinical exposure on medical students’ attitude toward their preparation for attending clinical setting. Material & Methods: In an interventional before -after study, 52 fourth semester medical students studying at Hamadan University of medical sciences were enrolled in the study. The participants filled out a self-structured questionnaire before and after taking part in a 4 month course in three different wards including: surgery, pediatric and internal wards . The staff’s opinions about the program were also gathered. Result: Mean attitude score increased significantly after taking part in the course in these areas: satisfaction about basic science lessons (P=0.019, understanding social determinants of health (P= 0.03 and understanding clinical thinking and simple clinical skills (P= 0.01. Passing the course did not have any significant effect in communication skills and current semester scores (P.0.05 in both issues. Forty one percent of the academic staff in the mentioned wards believed in the necessity of early clinical exposure in basic science stage, 29.5% denied it's necessity and 29.5% did not express their opinions. Conclusion: It seems that despite the mean score increase of some items, early clinical exposure program doesn’t have any positive effect on the measured items. Therefore, it is recommended to change the medical education program. Sci J Hamadan Univ Med Sci . 2016; 22 (4 :323-330

  9. Transmission Properties of Fiber Probes

    Institute of Scientific and Technical Information of China (English)

    XUE Chun-rong; ZHU Sheng-xiang; XIAO Zhi-gang

    2004-01-01

    Transmission properties of tapered fiber including right cone fiber and bend optical fiber are discussed. The transmission efficiency of the tapered fiber is measured. The curve of transmission efficiency versus taper cone angle is given. By the scalar wave equation and Gaussian approximation, transmission properties of the two kinds of tapered fibers are analyzed, the power losses caused by taper cone angle and by the bending are also calculated. From the experiments and theoretical analysis, it could come to a conclusion that the wider the taper cone angle is, the higher the transmission efficiency will be.

  10. [Oral transmission of Chagas' disease].

    Science.gov (United States)

    Toso M, Alberto; Vial U, Felipe; Galanti, Norbel

    2011-02-01

    The traditional transmission pathways of Chagas' disease are vectorial, transfusional, transplacental and organ transplantation. However, oral transmission is gaining importance. The first evidence of oral transmission was reported in Brazil in 1965. Nowadays the oral route is the transmission mode in 50% of cases in the Amazon river zone. Oral infection is produced by the ingestion of infected triatomine bugs or their feces, undercooked meat from infested host animals and food contaminated with urine or anal secretion of infected marsupials. Therefore travelers to those zones should be advised about care to be taken with ingested food. In Chile, this new mode of transmission should be considered in public health policies.

  11. Value Set Authority Center

    Data.gov (United States)

    U.S. Department of Health & Human Services — The VSAC provides downloadable access to all official versions of vocabulary value sets contained in the 2014 Clinical Quality Measures (CQMs). Each value set...

  12. Altimeter Setting Indicator

    Data.gov (United States)

    Department of Transportation — The Altimeter Setting Indicator (ASI) is an aneroid system used at airports to provide an altimeter setting for aircraft altimeters. This indicator may be an analog...

  13. Landslides, Set 2

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This set expands the topics included in Set 1 and includes (in addition to landslides) rockfalls, rock avalanches, mud flows, debris flows, slumps, creep, and...

  14. Broadband transmission EPR spectroscopy.

    Directory of Open Access Journals (Sweden)

    Wilfred R Hagen

    Full Text Available EPR spectroscopy employs a resonator operating at a single microwave frequency and phase-sensitive detection using modulation of the magnetic field. The X-band spectrometer is the general standard with a frequency in the 9-10 GHz range. Most (biomolecular EPR spectra are determined by a combination of the frequency-dependent electronic Zeeman interaction and a number of frequency-independent interactions, notably, electron spin - nuclear spin interactions and electron spin - electron spin interactions, and unambiguous analysis requires data collection at different frequencies. Extant and long-standing practice is to use a different spectrometer for each frequency. We explore the alternative of replacing the narrow-band source plus single-mode resonator with a continuously tunable microwave source plus a non-resonant coaxial transmission cell in an unmodulated external field. Our source is an arbitrary wave digital signal generator producing an amplitude-modulated sinusoidal microwave in combination with a broadband amplifier for 0.8-2.7 GHz. Theory is developed for coaxial transmission with EPR detection as a function of cell dimensions and materials. We explore examples of a doublet system, a high-spin system, and an integer-spin system. Long, straigth, helical, and helico-toroidal cells are developed and tested with dilute aqueous solutions of spin label hydroxy-tempo. A detection limit of circa 5 µM HO-tempo in water at 800 MHz is obtained for the present setup, and possibilities for future improvement are discussed.

  15. Eastern wind integration and transmission study overview

    Energy Technology Data Exchange (ETDEWEB)

    Corbus, D. [United States Dept. of Energy, Golden, CO (United States). National Renewable Energy Laboratory

    2009-07-01

    This presentation discussed the electricity system operational impacts and benefits of long distance transmission accessing multiple wind resources in New England. The aim of the eastern wind integration and transmission study (EWITS) was to determine the impact of geographical diversity on system variability, and to understand the role of wind forecasting in ensuring reliability. Mesoscale modelling was evaluated, as well as transmission and integration studies. Mesoscale modelling is conducted to identify wind sites and develop high quality wind resource data sets, as well as to develop wind power plant outputs. Scenarios for 20 and 30 per cent wind integration includes the development of local resources with lower capacity factors; and high capacity factor wind development with larger transmission components. All the scenarios required the use of offshore wind resources. The study also examined export capacity for each of the studied areas. Wind integration, reliability analyses, and hourly modelling approaches were reviewed. Future research will include sensitivity studies related to carbon pricing and stochastic modelling. tabs., figs.

  16. Vague集%Vague Set

    Institute of Scientific and Technical Information of China (English)

    李凡; 徐章艳; 饶勇

    2000-01-01

    In this paper,we first introduce vague set,then give the definition of intersection and union based on vague set with t-norm and t-conorm of the point value. Thus we gain some properties of intersection and union of vague set.

  17. Paired fuzzy sets

    DEFF Research Database (Denmark)

    Rodríguez, J. Tinguaro; Franco de los Ríos, Camilo; Gómez, Daniel

    2015-01-01

    In this paper we want to stress the relevance of paired fuzzy sets, as already proposed in previous works of the authors, as a family of fuzzy sets that offers a unifying view for different models based upon the opposition of two fuzzy sets, simply allowing the existence of different types...

  18. Axiomatic set theory

    CERN Document Server

    Suppes, Patrick

    1972-01-01

    This clear and well-developed approach to axiomatic set theory is geared toward upper-level undergraduates and graduate students. It examines the basic paradoxes and history of set theory and advanced topics such as relations and functions, equipollence, finite sets and cardinal numbers, rational and real numbers, and other subjects. 1960 edition.

  19. Rough Neutrosophic Sets

    OpenAIRE

    Said Broumi; Florentin Smarandache; Mamoni Dhar

    2013-01-01

     Both neutrosophic sets theory and rough sets theory are emerging as powerful tool for managing uncertainty, indeterminate, incomplete and imprecise information. In this paper we develop an hybrid structure called rough neutrosophic sets and studied their properties. 

  20. Sets, Planets, and Comets

    Science.gov (United States)

    Baker, Mark; Beltran, Jane; Buell, Jason; Conrey, Brian; Davis, Tom; Donaldson, Brianna; Detorre-Ozeki, Jeanne; Dibble, Leila; Freeman, Tom; Hammie, Robert; Montgomery, Julie; Pickford, Avery; Wong, Justine

    2013-01-01

    Sets in the game "Set" are lines in a certain four-dimensional space. Here we introduce planes into the game, leading to interesting mathematical questions, some of which we solve, and to a wonderful variation on the game "Set," in which every tableau of nine cards must contain at least one configuration for a player to pick up.

  1. Household Transmission of Vibrio cholerae in Bangladesh.

    Directory of Open Access Journals (Sweden)

    Jonathan D Sugimoto

    2014-11-01

    Full Text Available Vibrio cholerae infections cluster in households. This study's objective was to quantify the relative contribution of direct, within-household exposure (for example, via contamination of household food, water, or surfaces to endemic cholera transmission. Quantifying the relative contribution of direct exposure is important for planning effective prevention and control measures.Symptom histories and multiple blood and fecal specimens were prospectively collected from household members of hospital-ascertained cholera cases in Bangladesh from 2001-2006. We estimated the probabilities of cholera transmission through 1 direct exposure within the household and 2 contact with community-based sources of infection. The natural history of cholera infection and covariate effects on transmission were considered. Significant direct transmission (p-value<0.0001 occurred among 1414 members of 364 households. Fecal shedding of O1 El Tor Ogawa was associated with a 4.9% (95% confidence interval: 0.9%-22.8% risk of infection among household contacts through direct exposure during an 11-day infectious period (mean length. The estimated 11-day risk of O1 El Tor Ogawa infection through exposure to community-based sources was 2.5% (0.8%-8.0%. The corresponding estimated risks for O1 El Tor Inaba and O139 infection were 3.7% (0.7%-16.6% and 8.2% (2.1%-27.1% through direct exposure, and 3.4% (1.7%-6.7% and 2.0% (0.5%-7.3% through community-based exposure. Children under 5 years-old were at elevated risk of infection. Limitations of the study may have led to an underestimation of the true risk of cholera infection. For instance, available covariate data may have incompletely characterized levels of pre-existing immunity to cholera infection. Transmission via direct exposure occurring outside of the household was not considered.Direct exposure contributes substantially to endemic transmission of symptomatic cholera in an urban setting. We provide the first estimate of

  2. Interrupting the transmission of wild polioviruses with vaccines: immunological considerations.

    OpenAIRE

    Ghendon, Y.; Robertson, S. E.

    1994-01-01

    In 1988 the World Health Assembly set the goal of global poliomyelitis eradication by the year 2000. Substantial progress has been made, and 143 countries reported no poliomyelitis cases associated with the wild virus in 1993. This article reviews the immunological considerations relevant to interrupting the transmission of wild polioviruses with vaccines. Although serum immunity prevents poliomyelitis in the individual, it is local immunity that is important in preventing the transmission of...

  3. Transmission models and management of lymphatic filariasis elimination.

    Science.gov (United States)

    Michael, Edwin; Gambhir, Manoj

    2010-01-01

    The planning and evaluation of parasitic control programmes are complicated by the many interacting population dynamic and programmatic factors that determine infection trends under different control options. A key need is quantification about the status of the parasite system state at any one given timepoint and the dynamic change brought upon that state as an intervention program proceeds. Here, we focus on the control and elimination of the vector-borne disease, lymphatic filariasis, to show how mathematical models of parasite transmission can provide a quantitative framework for aiding the design of parasite elimination and monitoring programs by their ability to support (1) conducting rational analysis and definition of endpoints for different programmatic aims or objectives, including transmission endpoints for disease elimination, (2) undertaking strategic analysis to aid the optimal design of intervention programs to meet set endpoints under different endemic settings and (3) providing support for performing informed evaluations of ongoing programs, including aiding the formation of timely adaptive management strategies to correct for any observed deficiencies in program effectiveness. The results also highlight how the use of a model-based framework will be critical to addressing the impacts of ecological complexities, heterogeneities and uncertainties on effective parasite management and thereby guiding the development of strategies to resolve and overcome such real-world complexities. In particular, we underscore how this approach can provide a link between ecological science and policy by revealing novel tools and measures to appraise and enhance the biological controllability or eradicability of parasitic diseases. We conclude by emphasizing an urgent need to develop and apply flexible adaptive management frameworks informed by mathematical models that are based on learning and reducing uncertainty using monitoring data, apply phased or sequential

  4. Fuel, environmental, and transmission pricing considerations in a deregulated environment

    Science.gov (United States)

    Obessis, Emmanouil Vlassios

    The 1992 National Energy Policy Act drastically changed the traditional structure of the vertically integrated utility. To facilitate increased competition in the power utility sector, all markets related to power generation have been opened to free competition and trading. To survive in the new competitive environment, power producers need to reduce costs and increase efficiency. Fuel marketing strategies are thus, getting more aggressive and fuel markets are becoming more competitive, offering more options regarding fuel supplies and contracts. At the same time, the 1990 Clean Air Act Amendments are taking effect. Although tightening the emission standards, this legislation offers utilities a wider flexibility in choosing compliance strategies. It also set maximum annual allowable levels replacing the traditional uniform maximum emission rates. The bill also introduced the concept of marketable emission allowances and provided for the establishment of nationwide markets where allowances may be traded, sold, or purchased. Several fuel- and emission-constrained algorithms have been historically presented, but those two classes of constraints, in general, were handled independently. The multiobjective optimization model developed in this research work, concurrently satisfies sets of detailed fuel and emission limits, modeling in a more accurate way the fuel supply and environmental limitations and their complexities in the new deregulated operational environment. Development of the implementation software is an integral part of this research project. This software may be useful for both daily scheduling activities and short-term operational planning. A Lagrangian multipliers-based variant is used to solve the problem. Single line searches are used to update the multipliers, thus offering attractive execution times. This work also investigates the applicability of cooperative games to the problem of transmission cost allocation. Interest in game theory as a powerful

  5. Sets avoiding integral distances

    CERN Document Server

    Kurz, Sascha

    2012-01-01

    We study open point sets in Euclidean spaces $\\mathbb{R}^d$ without a pair of points an integral distance apart. By a result of Furstenberg, Katznelson, and Weiss such sets must be of Lebesgue upper density zero. We are interested in how large such sets can be in $d$-dimensional volume. We determine the lower and upper bounds for the volumes of the sets in terms of the number of their connected components and dimension, and also give some exact values. Our problem can be viewed as a kind of inverse to known problems on sets with pairwise rational or integral distances.

  6. Elements of set theory

    CERN Document Server

    Enderton, Herbert B

    1977-01-01

    This is an introductory undergraduate textbook in set theory. In mathematics these days, essentially everything is a set. Some knowledge of set theory is necessary part of the background everyone needs for further study of mathematics. It is also possible to study set theory for its own interest--it is a subject with intruiging results anout simple objects. This book starts with material that nobody can do without. There is no end to what can be learned of set theory, but here is a beginning.

  7. Generalization Rough Set Theory

    Institute of Scientific and Technical Information of China (English)

    XIAO Di; ZHANG Jun-feng; HU Shou-song

    2008-01-01

    In order to avoid the discretization in the classical rough set theory, a generlization rough set theory is proposed.At first, the degree of general importance of an attribute and attribute subsets are presented.Then, depending on the degree of general importance of attribute, the space distance can be measured with weighted method.At last, a generalization rough set theory based on the general near neighborhood relation is proposed.The proposed theory partitions the universe into the tolerant modules, and forms lower approximation and upper approximation of the set under general near neighborhood relationship, which avoids the discretization in Pawlak's rough set theory.

  8. Sensitivity analysis of the age-structured malaria transmission model

    Science.gov (United States)

    Addawe, Joel M.; Lope, Jose Ernie C.

    2012-09-01

    We propose an age-structured malaria transmission model and perform sensitivity analyses to determine the relative importance of model parameters to disease transmission. We subdivide the human population into two: preschool humans (below 5 years) and the rest of the human population (above 5 years). We then consider two sets of baseline parameters, one for areas of high transmission and the other for areas of low transmission. We compute the sensitivity indices of the reproductive number and the endemic equilibrium point with respect to the two sets of baseline parameters. Our simulations reveal that in areas of either high or low transmission, the reproductive number is most sensitive to the number of bites by a female mosquito on the rest of the human population. For areas of low transmission, we find that the equilibrium proportion of infectious pre-school humans is most sensitive to the number of bites by a female mosquito. For the rest of the human population it is most sensitive to the rate of acquiring temporary immunity. In areas of high transmission, the equilibrium proportion of infectious pre-school humans and the rest of the human population are both most sensitive to the birth rate of humans. This suggests that strategies that target the mosquito biting rate on pre-school humans and those that shortens the time in acquiring immunity can be successful in preventing the spread of malaria.

  9. SITE DESIGN SETTING IN SHAREPOINT

    Directory of Open Access Journals (Sweden)

    Oleksii V. Tebenko

    2010-10-01

    Full Text Available Creation and promotion of the site is one of way to implement of ICT in education. To build modern sites and large portals, to avoid the process of content creation and management tools, when new content is added, dynamic model for page building is used. The article deals with means and methods of dynamic page template in SharePoint. Purpose of the article is to analyze the key components of SharePoint for dynamic pages, such as setting and changing master pages, standard types of spaceholders master pages, setting aggregates content and consideration of standard types of SharePoint spaceholders.

  10. SHAREPOINT SITE CREATING AND SETTING

    Directory of Open Access Journals (Sweden)

    Oleksandr V. Tebenko

    2011-02-01

    Full Text Available Tools for sites building that offer users the ability to work together, an actual theme in information society and modern Web technologies. This article considers the SharePoint system, which enables to create sites of any complexity, including large portals with a complex structure of documents. Purpose of this article is to consider the main points of site creating and its setting with tools of SharePoint system, namely: a site template creating and configuring, web application environment to create and configure Web applications, change of existing and creation of new theme site, a web part setting.

  11. Noncomputable Spectral Sets

    CERN Document Server

    Teutsch, J

    2007-01-01

    It is possible to enumerate all computer programs. In particular, for every partial computable function, there is a shortest program which computes that function. f-MIN is the set of indices for shortest programs. In 1972, Meyer showed that f-MIN is Turing equivalent to 0'', the halting set with halting set oracle. This paper generalizes the notion of shortest programs, and we use various measures from computability theory to describe the complexity of the resulting "spectral sets." We show that under certain Godel numberings, the spectral sets are exactly the canonical sets 0', 0'', 0''', ... up to Turing equivalence. This is probably not true in general, however we show that spectral sets always contain some useful information. We show that immunity, or "thinness" is a useful characteristic for distinguishing between spectral sets. In the final chapter, we construct a set which neither contains nor is disjoint from any infinite arithmetic set, yet it is 0-majorized and contains a natural spectral set. Thus ...

  12. Near infrared transmission through clothing: applications in sensing and screening

    Science.gov (United States)

    Hutchins, D. A.; Canal, C. M.; Saleem, A.; Davis, L. A. J.; Green, R. J.

    2011-11-01

    Experiments have been performed to demonstrate that near infrared (NIR) transmission through a wide range of clothing materials is possible. Studies have shown that the characteristics of NIR transmission are affected by both the type of fibre used, and the weave pattern. A series of experiments has indicated that NIR transmission is also dependent on other variables such as fabric porosity and dye colour. It is shown that, in many cases, transmission coefficients are sufficiently high that imaging and spectroscopy of objects hidden behind clothing samples should be possible. However, while transmission through clothing at NIR wavelengths in the 750-1,700 nm range is often more effective than in the visible or IR regions, the fabrics themselves will modify the transmitted signal in terms of spatial effects, intensity and spectral content. The paper also describes the possible use of near infrared signals to identify objects that are hidden behind clothing layers. This can be done using spectroscopy. It is important, however, to distinguish the various contributions that exist within the backscattered signal. A set of careful laboratory experiments have demonstrated that transmission through a set of different clothing fabrics does modify the spectral content of signals, but that the spectrum of a particular chemical can still be identified, provided certain steps are taken. These involve a set of careful calibration measurements, and the use of processing techniques for the retrieval of data. It will be shown that this is possible for both granular solids and selected liquids.

  13. Stress transmission in soil

    DEFF Research Database (Denmark)

    Lamandé, Mathieu; Schjønning, Per

    We urgently need increased quantitative knowledge on stress transmission in real soils loaded with agricultural machinery. 3D measurements of vertical stresses under tracked wheels were performed in situ in a Stagnic Luvisol (clay content 20 %) continuously cropped with small grain cereals......). Seven load cells were inserted horizontally from a pit with minimal disturbance of soil in each of three depths (0.3, 0.6 and 0.9 m), covering the width of the wheeled area. The position of the wheel relative to the transducers was recorded using a laser sensor. Finally, the vertical stresses near...... the soil-tyre interface were measured in separate tests by 17 stress transducers across the width of the tyres. The results showed that the inflation pressure controlled the level of maximum stresses at 0.3 m depth, while the wheel load was correlated to the measured stresses at 0.9 m depth. This supports...

  14. Human immunodeficiency virus (HIV) transmission in dentistry.

    Science.gov (United States)

    Scully, C; Greenspan, J S

    2006-09-01

    HIV transmission in the health-care setting is of concern. To assess the current position in dentistry, we have reviewed the evidence to November 1, 2005. Transmission is evidently rare in the industrialized nations and can be significantly reduced or prevented by the use of standard infection control measures, appropriate clinical and instrument-handling procedures, and the use of safety equipment and safety needles. We hope that breaches in standard infection control will become vanishingly small. When occupational exposure to HIV is suspected, the application of post-exposure protocols for investigating the incident and protecting those involved from possible HIV infection further reduces the likelihood of HIV disease, and also stress and anxiety.

  15. Transmission of Information by Longitudinal Electromagnetic Waves

    CERN Document Server

    Barashenkov, V S; Yuriev, M Z

    2001-01-01

    In Maxwell electrodynamics longitudinal wave irradiation is strongly forbidden by the so-called gauge invariance. However, these waves are present in virtual quantum processes and they can be used to transfer information at macroscopic distances by the displacement of the interference picture due to the change of the phase of electron wave function. The transmission can be carried out so that it will be hidden for usual observation.

  16. Facts controllers in power transmission and distribution

    CERN Document Server

    Padiyar, KR

    2007-01-01

    About the Book: The emerging technology of Flexible AC Transmission System (FACTS) enables planning and operation of power systems at minimum costs, without compromising security. This is based on modern high power electronic systems that provide fast controllability to ensure ''flexible'' operation under changing system conditions. This book presents a comprehensive treatment of the subject by discussing the operating principles, mathematical models, control design and issues that affect the applications. The concepts are explained often with illustrative examples and case studies. In partic

  17. Droplets and modes of respiratory disease transmission

    Science.gov (United States)

    Bourouiba, Lydia

    2014-11-01

    Direct observation of violent expirations such as sneezes and coughs events reveal that such flows are multiphase turbulent buoyant clouds with suspended droplets of various sizes. The effects of ambient conditions indoors, such as moisture and temperature, coupled with the water content of such clouds are key in shaping the pathogen footprint emitted by potentially sick individuals. Such pathogen footprint can change the patterns of respiratory disease transmission. We discuss how the fluid dynamics of violent expirations can help inform how.

  18. Detecting emerging transmissibility of avian influenza virus in human households.

    Directory of Open Access Journals (Sweden)

    Michiel van Boven

    2007-07-01

    Full Text Available Accumulating infections of highly pathogenic H5N1 avian influenza in humans underlines the need to track the ability of these viruses to spread among humans. A human-transmissible avian influenza virus is expected to cause clusters of infections in humans living in close contact. Therefore, epidemiological analysis of infection clusters in human households is of key importance. Infection clusters may arise from transmission events from (i the animal reservoir, (ii humans who were infected by animals (primary human-to-human transmission, or (iii humans who were infected by humans (secondary human-to-human transmission. Here we propose a method of analysing household infection data to detect changes in the transmissibility of avian influenza viruses in humans at an early stage. The method is applied to an outbreak of H7N7 avian influenza virus in The Netherlands that was the cause of more than 30 human-to-human transmission events. The analyses indicate that secondary human-to-human transmission is plausible for the Dutch household infection data. Based on the estimates of the within-household transmission parameters, we evaluate the effectiveness of antiviral prophylaxis, and conclude that it is unlikely that all household infections can be prevented with current antiviral drugs. We discuss the applicability of our method for the detection of emerging human-to-human transmission of avian influenza viruses in particular, and for the analysis of within-household infection data in general.

  19. Topics in Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Within the last decade we have experienced deregulation of several industries, such as airlines, telecommunications and the electric utility industry, the last-mentioned being the focus of this work. Both the telecommunications and the electricity sector depend on network facilities, some of which are still considered as natural monopolies. In these industries, open network access is regarded as crucial in order to achieve the gains from increased competition, and transmission tariffs are important in implementing this. Based on the Energy Act that was introduced in 1991, Norway was among the first countries to restructure its electricity sector. On the supply side there are a large number of competing firms, almost exclusively hydro plants, with a combined capacity of about 23000 MW, producing 105-125 TWh per year, depending on the availability of water. Hydro plants are characterized by low variable costs of operation, however since water may be stored in dams, water has an opportunity cost, generally known as the water value, which is the shadow price of water when solving the generator's inter temporal profit maximization problem. Water values are the main factor of the producers' short run marginal cost. Total consumption amounts to 112-117 TWh a year, and consumers, even households, may choose their electricity supplier independent of the local distributor to which the customer is connected. In fact, approximately 10% of the households have actually changed supplier. The web-site www.konkurransetilsynet.no indicates available contracts, and www.dinside.no provides an ''energy-calculator'' where one can check whether it is profitable to switch supplier. If a customer buys energy from a remote supplier, the local distributor only provides transportation facilities for the energy and is compensated accordingly. Transmission and distribution have remained monopolized and regulated by the Norwegian Water Resources and Energy

  20. Topics on Electricity Transmission Pricing

    Energy Technology Data Exchange (ETDEWEB)

    Bjoerndal, Mette

    2000-02-01

    Within the last decade we have experienced deregulation of several industries, such as airlines, telecommunications and the electric utility industry, the last-mentioned being the focus of this work. Both the telecommunications and the electricity sector depend on network facilities, some of which are still considered as natural monopolies. In these industries, open network access is regarded as crucial in order to achieve the gains from increased competition, and transmission tariffs are important in implementing this. Based on the Energy Act that was introduced in 1991, Norway was among the first countries to restructure its electricity sector. On the supply side there are a large number of competing firms, almost exclusively hydro plants, with a combined capacity of about 23000 MW, producing 105-125 TWh per year, depending on the availability of water. Hydro plants are characterized by low variable costs of operation, however since water may be stored in dams, water has an opportunity cost, generally known as the water value, which is the shadow price of water when solving the generator's inter temporal profit maximization problem. Water values are the main factor of the producers' short run marginal cost. Total consumption amounts to 112-117 TWh a year, and consumers, even households, may choose their electricity supplier independent of the local distributor to which the customer is connected. In fact, approximately 10% of the households have actually changed supplier. The web-site www.konkurransetilsynet.no indicates available contracts, and www.dinside.no provides an ''energy-calculator'' where one can check whether it is profitable to switch supplier. If a customer buys energy from a remote supplier, the local distributor only provides transportation facilities for the energy and is compensated accordingly. Transmission and distribution have remained monopolized and regulated by the Norwegian Water Resources and Energy

  1. Feedback Control of Transmission Line by Static VAR Compensators (TSC & TCR Using Fuzzy Logic

    Directory of Open Access Journals (Sweden)

    Arushi Jaiswal

    2013-07-01

    Full Text Available Voltage profile maintenance of a transmission system can be done by using feedback control methodology and the compensation technique used is Static VAR compensation. This thesis describes a MATLAB based SIMULINK model that can be implemented in real time systems to maintain a constant voltage profile during load changes and fault conditions. In any power system the basic requirement is to keep the voltage of the system constant so that the load functions properly. Whenever there is a fault or any load is disconnected, the active and reactive power requirements of the system changes. As a result, the voltage of the system changes. Therefore to maintain a constant voltage profile shunt compensators are used near the load end, in the model presented in this project. Fuzzy logic is also implemented to set the proper compensation required

  2. International Transmission Under Bretton Woods

    OpenAIRE

    Alan C. Stockman

    1992-01-01

    This paper explores the main channels of international transmission of economic disturbances under the Bretton Woods System and presents evidence on the short-run international transmission of inflation under that system. There appears to have been little short-run international transmission of inflation. Countries with one-percent higher money-growth rates subsequently had one-fourth to one-half percent higher inflation and a (predictably) lower real interest rate. This probably reflects eff...

  3. An Insight on Right of Way and its Cost for Power Transmission Cable and Conventional Overhead Transmission Lines

    Science.gov (United States)

    Khandelwal, P.; Pachori, A.; Khandelwal, T.

    2013-12-01

    This paper provides the complete information related to Right of Way (RoW) for the construction of new power transmission line (TL) in terms of present cost for overhead transmission line and underground XLPE transmission cable. The former part of the paper describes the general procedure and rules for acquisition of land for RoW by transmission asset owner (TAO) while in the later part the cost associated to acquire RoW and its impact on the cost of adjacent land have been detailed. It also discusses the actual dismantling cost including the cost of waste metal what TAO get after completion of lifecycle of TL due to increase in metal prices. In this paper cost of RoW after completion of lifecycle of TL is also highlighted. This paper compares the cost of RoW for overhead transmission line and underground XLPE transmission cable for construction of new TL. Also for old transmission infrastructure cost of RoW for change from overhead transmission line to underground XLPE transmission cable is detailed by application of replacement model.

  4. Horizontal versus familial transmission of Helicobacter pylori.

    Directory of Open Access Journals (Sweden)

    Sandra Schwarz

    2008-10-01

    Full Text Available Transmission of Helicobacter pylori is thought to occur mainly during childhood, and predominantly within families. However, due to the difficulty of obtaining H. pylori isolates from large population samples and to the extensive genetic diversity between isolates, the transmission and spread of H. pylori remain poorly understood. We studied the genetic relationships of H. pylori isolated from 52 individuals of two large families living in a rural community in South Africa and from 43 individuals of 11 families living in urban settings in the United Kingdom, the United States, Korea, and Colombia. A 3,406 bp multilocus sequence haplotype was determined for a total of 142 H. pylori isolates. Isolates were assigned to biogeographic populations, and recent transmission was measured as the occurrence of non-unique isolates, i.e., isolates whose sequences were identical to those of other isolates. Members of urban families were almost always infected with isolates from the biogeographic population that is common in their location. Non-unique isolates were frequent in urban families, consistent with familial transmission between parents and children or between siblings. In contrast, the diversity of H. pylori in the South African families was much more extensive, and four distinct biogeographic populations circulated in this area. Non-unique isolates were less frequent in South African families, and there was no significant correlation between kinship and similarity of H. pylori sequences. However, individuals who lived in the same household did have an increased probability of carrying the same non-unique isolates of H. pylori, independent of kinship. We conclude that patterns of spread of H. pylori under conditions of high prevalence, such as the rural South African families, differ from those in developed countries. Horizontal transmission occurs frequently between persons who do not belong to a core family, blurring the pattern of familial

  5. The interior transmission problem and bounds on transmission eigenvalues

    CERN Document Server

    Hitrik, Michael; Ola, Petri; Päivärinta, Lassi

    2010-01-01

    We study the interior transmission eigenvalue problem for sign-definite multiplicative perturbations of the Laplacian in a bounded domain. We show that all but finitely many complex transmission eigenvalues are confined to a parabolic neighborhood of the positive real axis.

  6. Descriptive set theory

    CERN Document Server

    Moschovakis, YN

    1987-01-01

    Now available in paperback, this monograph is a self-contained exposition of the main results and methods of descriptive set theory. It develops all the necessary background material from logic and recursion theory, and treats both classical descriptive set theory and the effective theory developed by logicians.

  7. China Sets Resources Strategy

    Institute of Scientific and Technical Information of China (English)

    LiMin

    2003-01-01

    All mineral mining in China now has a set road to follow, and straying off its path will attract severe penalties. The country's first-round programs for provincial mineral resources exploitation took effect in mid-January, setting output goals and designating mining regions.

  8. Acoustic data transmission method

    Energy Technology Data Exchange (ETDEWEB)

    Duckworth, A.

    1991-09-17

    This patent describes a method for transmitting time line data through a drillstring having drill pipe sections connected end-to-end by joints from a first location below the surface of the earth to a second location at or near the surface of the earth, the length and cross-sectional area of the drill pipe sections being different from the length and cross-sectional area of the joints. It comprises generating acoustic data signals having a single frequency content in at least one passband of the drillstring; transmitting the data signals through the drillstring from either the first location to the second location or from the second location to the first location during a time period prior to the onset of reflective interference caused by the data signals reflecting from along the length of the drillstring, the time period being equal to or less than the time for the data signals to travel three lengths of the drillstring; stopping the transmission of data signals at the onset of the reflective interference and allowing the acoustic signals to substantially attenuate; and detecting the data signals at the respective first or second location.

  9. EC Transmission Line Materials

    Energy Technology Data Exchange (ETDEWEB)

    Bigelow, Tim S [ORNL

    2012-05-01

    The purpose of this document is to identify materials acceptable for use in the US ITER Project Office (USIPO)-supplied components for the ITER Electron cyclotron Heating and Current Drive (ECH&CD) transmission lines (TL), PBS-52. The source of material property information for design analysis shall be either the applicable structural code or the ITER Material Properties Handbook. In the case of conflict, the ITER Material Properties Handbook shall take precedence. Materials selection, and use, shall follow the guidelines established in the Materials Assessment Report (MAR). Materials exposed to vacuum shall conform to the ITER Vacuum Handbook. [Ref. 2] Commercial materials shall conform to the applicable standard (e.g., ASTM, JIS, DIN) for the definition of their grade, physical, chemical and electrical properties and related testing. All materials for which a suitable certification from the supplier is not available shall be tested to determine the relevant properties, as part of the procurement. A complete traceability of all the materials including welding materials shall be provided. Halogenated materials (example: insulating materials) shall be forbidden in areas served by the detritiation systems. Exceptions must be approved by the Tritium System and Safety Section Responsible Officers.

  10. The Greenhouse Gas Climate Change Initiative (GHG-CCI): comparison and quality assessment of near-surface-sensitive satellite-derived CO2 and CH4 global data sets

    Science.gov (United States)

    Buchwitz, Michael

    2013-04-01

    The GHG-CCI project is one of several projects of the European Space Agency's (ESA) Climate Change Initiative (CCI). The goal of the CCI is to generate and deliver data sets of various satellite-derived Essential Climate Variables (ECVs) in line with GCOS (Global Climate Observing System) requirements. The "ECV Greenhouse Gases" (ECV GHG) is the global distribution of important climate relevant gases - atmospheric CO2 and CH4 - with a quality sufficient to obtain information on regional CO2 and CH4 sources and sinks. Two satellite instruments deliver the main input data for GHG-CCI: SCIAMACHY/ENVISAT and TANSO-FTS/GOSAT. The first order priority goal of GHG-CCI is the further development of retrieval algorithms for near-surface-sensitive column-averaged dry air mole fractions of CO2 and CH4, denoted XCO2 and XCH4, to meet the demanding user requirements. GHG-CCI focusses on four core data products: XCO2 from SCIAMACHY and TANSO and XCH4 from the same two sensors. For each of the four core data products at least two candidate retrieval algorithms have been independently further developed and the corresponding data products have been quality assessed and inter-compared. This activity is referred to as "Round Robin" (RR) activity within the CCI. The main goal of the RR was to identify for each of the four core products which algorithm to be used to generate the Climate Research Data Package (CRDP), which will essentially be the first version of the ECV GHG. This manuscript gives an overview about the GHG-CCI RR and related activities. This comprises the establishment of the user requirements, the improvement of the candidate retrieval algorithms and comparisons with ground-based observations and models. The manuscript summarizes the final RR algorithm selection decision and its justification. Comparison with ground-based Total Carbon Column Observing Network (TCCON) data indicates that the "breakthrough" single measurement precision requirement has been met for

  11. Generation and tooth contact analysis of spiral bevel gears with predesigned parabolic functions of transmission errors

    Science.gov (United States)

    Litvin, Faydor L.; Lee, Hong-Tao

    1989-01-01

    A new approach for determination of machine-tool settings for spiral bevel gears is proposed. The proposed settings provide a predesigned parabolic function of transmission errors and the desired location and orientation of the bearing contact. The predesigned parabolic function of transmission errors is able to absorb piece-wise linear functions of transmission errors that are caused by the gear misalignment and reduce gear noise. The gears are face-milled by head cutters with conical surfaces or surfaces of revolution. A computer program for simulation of meshing, bearing contact and determination of transmission errors for misaligned gear has been developed.

  12. HVDC power transmission technology assessment

    Energy Technology Data Exchange (ETDEWEB)

    Hauth, R.L.; Tatro, P.J.; Railing, B.D. [New England Power Service Co., Westborough, MA (United States); Johnson, B.K.; Stewart, J.R. [Power Technologies, Inc., Schenectady, NY (United States); Fink, J.L.

    1997-04-01

    The purpose of this study was to develop an assessment of the national utility system`s needs for electric transmission during the period 1995-2020 that could be met by future reduced-cost HVDC systems. The assessment was to include an economic evaluation of HVDC as a means for meeting those needs as well as a comparison with competing technologies such as ac transmission with and without Flexible AC Transmission System (FACTS) controllers. The role of force commutated dc converters was to be assumed where appropriate. The assessment begins by identifying the general needs for transmission in the U.S. in the context of a future deregulated power industry. The possible roles for direct current transmission are then postulated in terms of representative scenarios. A few of the scenarios are illustrated with the help of actual U.S. system examples. non-traditional applications as well as traditional applications such as long lines and asynchronous interconnections are discussed. The classical ``break-even distance`` concept for comparing HVDC and ac lines is used to assess the selected scenarios. The impact of reduced-cost converters is reflected in terms of the break-even distance. This report presents a comprehensive review of the functional benefits of HVDC transmission and updated cost data for both ac and dc system components. It also provides some provocative thoughts on how direct current transmission might be applied to better utilize and expand our nation`s increasingly stressed transmission assets.

  13. Regional Transmission Projects: Finding Solutions

    Energy Technology Data Exchange (ETDEWEB)

    The Keystone Center

    2005-06-15

    The Keystone Center convened and facilitated a year-long Dialogue on "Regional Transmission Projects: Finding Solutions" to develop recommendations that will help address the difficult and contentious issues related to expansions of regional electric transmission systems that are needed for reliable and economic transmission of power within and across regions. This effort brought together a cross-section of affected stakeholders and thought leaders to address the problem with the collective wisdom of their experience and interests. Transmission owners sat at the table with consumer advocates and environmental organizations. Representatives from regional transmission organizations exchanged ideas with state and federal regulators. Generation developers explored common interests with public power suppliers. Together, the Dialogue participants developed consensus solutions about how to begin unraveling some of the more intractable issues surrounding identification of need, allocation of costs, and reaching consensus on siting issues that can frustrate the development of regional transmission infrastructure. The recommendations fall into three broad categories: 1. Recommendations on appropriate institutional arrangements and processes for achieving regional consensus on the need for new or expanded transmission infrastructure 2. Recommendations on the process for siting of transmission lines 3. Recommendations on the tools needed to support regional planning, cost allocation, and siting efforts. List of Dialogue participants: List of Dialogue Participants: American Electric Power American Transmission Company American Wind Energy Association California ISO Calpine Corporation Cinergy Edison Electric Institute Environmental Defense Federal Energy Regulatory Commission Great River Energy International Transmission Company ISO-New England Iowa Public Utility Board Kanner & Associates Midwest ISO National Association of Regulatory Utility Commissioners National Association

  14. Energy Transmission and Infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Mathison, Jane

    2012-12-31

    The objective of Energy Transmission and Infrastructure Northern Ohio (OH) was to lay the conceptual and analytical foundation for an energy economy in northern Ohio that will: • improve the efficiency with which energy is used in the residential, commercial, industrial, agricultural, and transportation sectors for Oberlin, Ohio as a district-wide model for Congressional District OH-09; • identify the potential to deploy wind and solar technologies and the most effective configuration for the regional energy system (i.e., the ratio of distributed or centralized power generation); • analyze the potential within the district to utilize farm wastes to produce biofuels; • enhance long-term energy security by identifying ways to deploy local resources and building Ohio-based enterprises; • identify the policy, regulatory, and financial barriers impeding development of a new energy system; and • improve energy infrastructure within Congressional District OH-09. This objective of laying the foundation for a renewable energy system in Ohio was achieved through four primary areas of activity: 1. district-wide energy infrastructure assessments and alternative-energy transmission studies; 2. energy infrastructure improvement projects undertaken by American Municipal Power (AMP) affiliates in the northern Ohio communities of Elmore, Oak Harbor, and Wellington; 3. Oberlin, OH-area energy assessment initiatives; and 4. a district-wide conference held in September 2011 to disseminate year-one findings. The grant supported 17 research studies by leading energy, policy, and financial specialists, including studies on: current energy use in the district and the Oberlin area; regional potential for energy generation from renewable sources such as solar power, wind, and farm-waste; energy and transportation strategies for transitioning the City of Oberlin entirely to renewable resources and considering pedestrians, bicyclists, and public transportation as well as drivers

  15. Combinatorics of set partitions

    CERN Document Server

    Mansour, Toufik

    2012-01-01

    Focusing on a very active area of mathematical research in the last decade, Combinatorics of Set Partitions presents methods used in the combinatorics of pattern avoidance and pattern enumeration in set partitions. Designed for students and researchers in discrete mathematics, the book is a one-stop reference on the results and research activities of set partitions from 1500 A.D. to today. Each chapter gives historical perspectives and contrasts different approaches, including generating functions, kernel method, block decomposition method, generating tree, and Wilf equivalences. Methods and d

  16. Basic set theory

    CERN Document Server

    Levy, Azriel

    2002-01-01

    An advanced-level treatment of the basics of set theory, this text offers students a firm foundation, stopping just short of the areas employing model-theoretic methods. Geared toward upper-level undergraduate and graduate students, it consists of two parts: the first covers pure set theory, including the basic motions, order and well-foundedness, cardinal numbers, the ordinals, and the axiom of choice and some of it consequences; the second deals with applications and advanced topics such as point set topology, real spaces, Boolean algebras, and infinite combinatorics and large cardinals. An

  17. Set theory essentials

    CERN Document Server

    Milewski, Emil G

    2012-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Set Theory includes elementary logic, sets, relations, functions, denumerable and non-denumerable sets, cardinal numbers, Cantor's theorem, axiom of choice, and order relations.

  18. Determination of the sputter rate variation pattern of a silicon carbide target for radio frequency magnetron sputtering using optical transmission measurements

    Energy Technology Data Exchange (ETDEWEB)

    Galvez de la Puente, G. [Departamento de Ciencias, Seccion Fisica, Pontificia Universidad Catolica del Peru, Av. Universitaria 1801, Apartado Postal 1761, Lima 32 (Peru); Department of Materials Science 6, University of Erlangen, Martensstrasse 7, 91058-Erlangen (Germany); Guerra Torres, J.A. [Departamento de Ciencias, Seccion Fisica, Pontificia Universidad Catolica del Peru, Av. Universitaria 1801, Apartado Postal 1761, Lima 32 (Peru); Erlenbach, O. [Departamento de Ciencias, Seccion Fisica, Pontificia Universidad Catolica del Peru, Av. Universitaria 1801, Apartado Postal 1761, Lima 32 (Peru); Department of Materials Science 6, University of Erlangen, Martensstrasse 7, 91058-Erlangen (Germany); Steidl, M. [Department of Materials Science 6, University of Erlangen, Martensstrasse 7, 91058-Erlangen (Germany); Weingaertner, R., E-mail: rolandw@fisica.pucp.edu.pe [Departamento de Ciencias, Seccion Fisica, Pontificia Universidad Catolica del Peru, Av. Universitaria 1801, Apartado Postal 1761, Lima 32 (Peru); Department of Materials Science 6, University of Erlangen, Martensstrasse 7, 91058-Erlangen (Germany); De Zela, F. [Departamento de Ciencias, Seccion Fisica, Pontificia Universidad Catolica del Peru, Av. Universitaria 1801, Apartado Postal 1761, Lima 32 (Peru); Winnacker, A. [Department of Materials Science 6, University of Erlangen, Martensstrasse 7, 91058-Erlangen (Germany)

    2010-10-25

    We produce amorphous silicon carbide thin films (a-SiC) by radio frequency (rf) magnetron sputtering from SiC bulk target. We present the emission pattern of the rf magnetron with SiC target as a function of process parameters, like target sample distance, rf power, sputtering rate and process gas pressure. The emission pattern is determined by means of thickness distribution of the deposited a-SiC films obtained from optical transmission measurements using a slightly improved method of Swanepoel concerning the determination of construction of the envelopes in the interference pattern of the transmission spectra. A calibration curve is presented which allows the conversion of integrated transmission to film thickness. Holding constant a set of process parameters and only varying the target sample distance the emission pattern of the rf magnetron with SiC target was determined, which allowed us to predict the deposition rate distribution for a wide range of process parameters and target geometry. In addition, we have found that the transmission spectra of the a-SiC films change with time and saturate after approximately 10 days. Within this process no change in thickness is involved, so that the determination of thickness using transmission data is justified.

  19. Effect of Temperature-frequency on Transmission Parameters of Coaxial Cable%温度-频率对同轴电缆传输参数的影响

    Institute of Scientific and Technical Information of China (English)

    杨建保; 李春泉; 黄红艳; 张明; 邹梦强

    2015-01-01

    针对汽车信号传输线在温度-频率变化下的信号传输性能问题 ,应用节点电压法建立环境温度下同轴电缆的等效热路模型 ,分析并得出信号传输线在焦耳热和环境温度共同影响下的温度分布.通过实例分析 ,揭示了信号传输线传输参数随温度-频率的变化规律.%For the analysis of signal transmission performance of automotive signal transmission lines in temperature-frequency change ,the equivalent thermal circuit model of the coaxial cable is set up by use of the node voltage method ,which takes environ-ment temperature into account .The temperature distribution of signal transmission lines in the combined effect of Joule heating and environment temperature is analyzed and obtained .Through the case analysis ,the change law of transmission parameters of signal transmission lines with temperature-frequency is revealed .

  20. Pricing and Capacity Planning Problems in Energy Transmission Networks

    DEFF Research Database (Denmark)

    Villumsen, Jonas Christoffer

    Efficient use of energy is an increasingly important topic. Environmental and climate concerns as well as concerns for security of supply has made renewable energy sources a viable alternative to traditional energy sources. However, the intermittent nature of for instance wind and solar energy...... necessitates a radical change in the way we plan and operate energy systems. Another paradigm change which began in the 1990’s for electricity systems is that of deregulation. This has led to a variety of different market structures implemented across the world. In this thesis we discuss capacity planning...... and transmission pricing problems in energy transmission networks. Although the modelling framework applies to energy networks in general, most of the applications discussed concern the transmission of electricity. A number of the problems presented involves transmission switching, which allows the operator...

  1. Interference-Robust Transmission in Wireless Sensor Networks.

    Science.gov (United States)

    Han, Jin-Seok; Lee, Yong-Hwan

    2016-11-14

    Low-power wireless sensor networks (WSNs) operating in unlicensed spectrum bands may seriously suffer from interference from other coexisting radio systems, such as IEEE 802.11 wireless local area networks. In this paper, we consider the improvement of the transmission performance of low-power WSNs by adjusting the transmission rate and the payload size in response to the change of co-channel interference. We estimate the probability of transmission failure and the data throughput and then determine the payload size to maximize the throughput performance. We investigate that the transmission time maximizing the normalized throughput is not much affected by the transmission rate, but rather by the interference condition. We adjust the transmission rate and the transmission time in response to the change of the channel and interference condition, respectively. Finally, we verify the performance of the proposed scheme by computer simulation. The simulation results show that the proposed scheme significantly improves data throughput compared with conventional schemes while preserving energy efficiency even in the presence of interference.

  2. Transmission of Electric Energy Along Long Lines

    Directory of Open Access Journals (Sweden)

    Berzan V.P.

    2009-08-01

    Full Text Available Transmission of electric energy along long lines is examined and characteristics of the change of capacities at the beginning and at the end of a line are submitted: factor of capacity, efficiency of a transmission line, currents depending on length, parameters of a line and parameters of loading. Influence of losses upon the dynamics of instant values of voltages and currents in the opened and short-circuited long lines is investigated and effects of nonlinearity in such chains are revealed at a power supply from a sinusoidal source of voltage. It is shown, that the method of complex amplitudes is not always applicable for the calculation of modes in long lines.

  3. Vibration signature analysis of multistage gear transmission

    Science.gov (United States)

    Choy, F. K.; Tu, Y. K.; Savage, M.; Townsend, D. P.

    1989-01-01

    An analysis is presented for multistage multimesh gear transmission systems. The analysis predicts the overall system dynamics and the transmissibility to the gear box or the enclosed structure. The modal synthesis approach of the analysis treats the uncoupled lateral/torsional model characteristics of each stage or component independently. The vibration signature analysis evaluates the global dynamics coupling in the system. The method synthesizes the interaction of each modal component or stage with the nonlinear gear mesh dynamics and the modal support geometry characteristics. The analysis simulates transient and steady state vibration events to determine the resulting torque variations, speeds, changes, rotor imbalances, and support gear box motion excitations. A vibration signature analysis examines the overall dynamic characteristics of the system, and the individual model component responses. The gear box vibration analysis also examines the spectral characteristics of the support system.

  4. MONETARY POLICY TRANSMISSION MECHANISM IN EMERGING COUNTRIES

    Directory of Open Access Journals (Sweden)

    Andreea ROŞOIU

    2013-06-01

    Full Text Available The transmission channels of monetary policy are used by central banks to accomplish the main objective of price stability in the context of sustainable economic growth. The importance of interest rate and exchange rate channels for the emerging countries Romania, Poland, Czech Republic and Hungary is analyzed by using Bayesian VAR approach with Diffuse priors over 1998Q1-2012Q3. Main result of the empirical study is that both channels are effective for the monetary policy transmission mechanism in Hungary and Czech Republic. In Romania and Poland they do not exhibit puzzles, but the impact of the macroeconomic variables is not very significant and shows very high volatility. In the context of monetary integration, exchange rate channel will become irrelevant when these countries adopt Euro currency. This change will lead instead to a powerful interest rate channel.

  5. The Transmission of Chinese Medicine in Australia

    Directory of Open Access Journals (Sweden)

    Mary Garvey

    2011-09-01

    Full Text Available The paper explores some of the issues concerning the transmission of Chinese medicine in Australia, its practitioner training and the future of Chinese medicine as a distinct medical discipline in the Australian context. In China over the last century Chinese medicine was overhauled in order to align it with the biomedical perspective prevalent in the West. These changes, in turn, had important consequences for the transmission of CM in Australia and the West. But while the biomedicalisation of CM has offered the path of least resistance, it has also lead to unworkable simplifications and methodological failures. The paper thus argues for a renewed access to the tradition’s primary sources in order to ally the distinctive features and methods of traditional practice with biomedicine, as an alternative to an outright integration into biomedical practice.

  6. Financial Market Turmoil: Implications for Monetary Policy Transmission in China

    Institute of Scientific and Technical Information of China (English)

    Chengsi Zhang; Joel Clovis

    2009-01-01

    The recent financial market turmoil has initiated another search for insightful understanding of the interactions between the financial market and monetary policy. This paper explores these interactions in terms of the transmission mechanism of monetary policy in China. We argue that evolving financial development, enhanced by the expansion of the financial market, has altered the conventional channel for monetary transmission in China. Analyzing marked changes in the financial landscape and taking into account policy regime shifts in China, the paper provides clear evidence showing that the financial market has become a new and important channel for transmission of monetury policy in China.

  7. Long distance transmission through distributed erbium-doped fibers

    DEFF Research Database (Denmark)

    Rottwitt, Karsten; Povlsen, Jørn Hedegaard; Bjarklev, Anders Overgaard

    1993-01-01

    High bit rate, all-optical long-distance transmission could be created through the combined use of loss-compensating gain in erbium-doped fibers and solitons. A detailed analysis of the distributed erbium-doped fiber, including the spectral-gain dependency, is combined with an optimum design...... of the transmission fiber and general bit-error-rate calculations. Changes in wavenumber, group velocity, and fiber dispersion due to erbium doping in a single-mode fiber are evaluated, and a reduction in bit-error rates due to the erbium spectral-gain profile is shown. Transmission through distributed erbium...

  8. Adaptive Sensing and Transmission Durations for Cognitive Radios

    CERN Document Server

    Afifi, Wessam; Nafie, Mohammed

    2010-01-01

    In a cognitive radio setting, secondary users opportunistically access the spectrum allocated to primary users. Finding the optimal sensing and transmission durations for the secondary users becomes crucial in order to maximize the secondary throughput while protecting the primary users from interference and service disruption. In this paper an adaptive sensing and transmission scheme for cognitive radios is proposed. We consider a channel allocated to a primary user which operates in an unslotted manner switching activity at random times. A secondary transmitter adapts its sensing and transmission durations according to its belief regarding the primary user state of activity. The objective is to maximize a secondary utility function. This function has a penalty term for collisions with primary transmission. It accounts for the reliability-throughput tradeoff by explicitly incorporating the impact of sensing duration on secondary throughput and primary activity detection reliability. It also accounts for thro...

  9. Transmissibility-Based Operational Modal Analysis: Enhanced Stabilisation Diagrams

    Directory of Open Access Journals (Sweden)

    Gert De Sitter

    2012-01-01

    Full Text Available Recently it has been shown that also transmissibilities can be used to identify the modal parameters. This approach has several advantages: because of the deterministic character of the transmissibility functions, the estimated parameters are more accurate than the results obtained with the power spectra based operational modal analysis techniques. Another advantage is that the transmissibility functions do not depend on the colouring of the unknown forces. A disadvantage of the transmissibility based operational modal analysis techniques is that non-physical modes show up in the stabilisation diagrams. In this contribution it will first be shown that those non-physical modes will show up when traditional stabilisation diagrams are used. In a second step, a new approach of selecting the physical modes out of a set of estimated modes will be discussed and the new approach will be validated using data generated with an acoustical Finite Element Model. Finally, the approach will be validated using real acoustical data.

  10. Lebesgue Sets Immeasurable Existence

    Directory of Open Access Journals (Sweden)

    Diana Marginean Petrovai

    2012-12-01

    Full Text Available It is well known that the notion of measure and integral were released early enough in close connection with practical problems of measuring of geometric figures. Notion of measure was outlined in the early 20th century through H. Lebesgue’s research, founder of the modern theory of measure and integral. It was developed concurrently a technique of integration of functions. Gradually it was formed a specific area todaycalled the measure and integral theory. Essential contributions to building this theory was made by a large number of mathematicians: C. Carathodory, J. Radon, O. Nikodym, S. Bochner, J. Pettis, P. Halmos and many others. In the following we present several abstract sets, classes of sets. There exists the sets which are not Lebesgue measurable and the sets which are Lebesgue measurable but are not Borel measurable. Hence B ⊂ L ⊂ P(X.

  11. HEDIS Limited Data Set

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Healthcare Effectiveness Data and Information Set (HEDIS) is a tool used by more than 90 percent of Americas health plans to measure performance on important...

  12. Landslides, Set 1

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This set of slides graphically illustrates the potential danger that major earthquakes pose to school structures and to the children and adults who happen to be...

  13. Mixed raster content segmentation, compression, transmission

    CERN Document Server

    Pavlidis, George

    2017-01-01

    This book presents the main concepts in handling digital images of mixed content, traditionally referenced as mixed raster content (MRC), in two main parts. The first includes introductory chapters covering the scientific and technical background aspects, whereas the second presents a set of research and development approaches to tackle key issues in MRC segmentation, compression and transmission. The book starts with a review of color theory and the mechanism of color vision in humans. In turn, the second chapter reviews data coding and compression methods so as to set the background and demonstrate the complexity involved in dealing with MRC. Chapter three addresses the segmentation of images through an extensive literature review, which highlights the various approaches used to tackle MRC segmentation. The second part of the book focuses on the segmentation of color images for optimized compression, including multi-layered decomposition and representation of MRC and the processes that can be employed to op...

  14. Analysis of HIV early infant diagnosis data to estimate rates of perinatal HIV transmission in Zambia.

    Directory of Open Access Journals (Sweden)

    Kwasi Torpey

    -chemoprophylactic factors also play a significant role in HIV transmission. The overall change in the proportions of positive PCR results over time is more likely an indication of better PMTCT implementation. Determination of the outcomes of PMTCT in program settings is feasible but requires accurate documentation and analysis.

  15. SOME PARTICULARITIES OF THE MONETARY TRANSMISSION CHANNELS IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Ramona DUMITRIU

    2009-10-01

    Full Text Available In the last decade the monetary policy from Romania was deeply changed. The inflation decreased considerably in comparison with the 1990s. From a few years National Bank of Romania adopted the inflation targeting strategy that implied a careful use of the monetary instruments. The success of the Central Bank depends greatly on understanding the monetary transmission mechanism. Using the VAR methodology, we analyze in this article the particularities of the monetary transmission mechanism in Romania.

  16. Multicriteria identification sets method

    Science.gov (United States)

    Kamenev, G. K.

    2016-11-01

    A multicriteria identification and prediction method for mathematical models of simulation type in the case of several identification criteria (error functions) is proposed. The necessity of the multicriteria formulation arises, for example, when one needs to take into account errors of completely different origins (not reducible to a single characteristic) or when there is no information on the class of noise in the data to be analyzed. An identification sets method is described based on the approximation and visualization of the multidimensional graph of the identification error function and sets of suboptimal parameters. This method allows for additional advantages of the multicriteria approach, namely, the construction and visual analysis of the frontier and the effective identification set (frontier and the Pareto set for identification criteria), various representations of the sets of Pareto effective and subeffective parameter combinations, and the corresponding predictive trajectory tubes. The approximation is based on the deep holes method, which yields metric ɛ-coverings with nearly optimal properties, and on multiphase approximation methods for the Edgeworth-Pareto hull. The visualization relies on the approach of interactive decision maps. With the use of the multicriteria method, multiple-choice solutions of identification and prediction problems can be produced and justified by analyzing the stability of the optimal solution not only with respect to the parameters (robustness with respect to data) but also with respect to the chosen set of identification criteria (robustness with respect to the given collection of functionals).

  17. Set theory and physics

    Energy Technology Data Exchange (ETDEWEB)

    Svozil, K. [Univ. of Technology, Vienna (Austria)

    1995-11-01

    Inasmuch as physical theories are formalizable, set theory provides a framework for theoretical physics. Four speculations about the relevance of set theoretical modeling for physics are presented: the role of transcendental set theory (i) in chaos theory, (ii) for paradoxical decompositions of solid three-dimensional objects, (iii) in the theory of effective computability (Church-Turing thesis) related to the possible {open_quotes}solution of supertasks,{close_quotes} and (iv) for weak solutions. Several approaches to set theory and their advantages and disadvantages for physical applications are discussed: Cantorian {open_quotes}naive{close_quotes} (i.e., nonaxiomatic) set theory, contructivism, and operationalism. In the author`s opinion, an attitude, of {open_quotes}suspended attention{close_quotes} (a term borrowed from psychoanalysis) seems most promising for progress. Physical and set theoretical entities must be operationalized wherever possible. At the same time, physicists should be open to {open_quotes}bizarre{close_quotes} or {open_quotes}mindboggling{close_quotes} new formalisms, which need not be operationalizable or testable at the time of their creation, but which may successfully lead to novel fields of phenomenology and technology.

  18. Informational Asymmetries and the International Transmission of Business Cycles

    Directory of Open Access Journals (Sweden)

    Patricio Mujica

    1988-03-01

    Full Text Available Informational Asymmetries and the International Transmission of Business Cycles Several recent papers have analyzed the international transmission of economic disturbances in a context in which all goods are traded. Additionaly, those papers assume alternatively full contemporaneous infomation on financial variables is not available at all. A key feature of the model is that agent in each country observe all those variables directly linked with the markets in wich they usuallyy trade but they do not have access to the infomation provided by the market for nontraded goods in the foreign countrv. Therefore. the introduction of nontreded goods provides a natural settings for assuming an asymmetry in the information set available to agents across countries. It is shown that this asymmetry is crucial for the existence of real effects associated with monetary shocks and also for the nature of the international transmission  of business cycles across countries.

  19. Parenting with Style: Altruism and Paternalism in Intergenerational Preference Transmission

    OpenAIRE

    Matthias Doepke; Fabrizio Zilibotti

    2014-01-01

    We develop a theory of intergenerational transmission of preferences that rationalizes the choice between alternative parenting styles (as set out in Baumrind 1967). Parents maximize an objective function that combines Beckerian altruism and paternalism towards children. They can affect their children’s choices via two channels: either by influencing children’s preferences or by imposing direct restrictions on their choice sets. Different parenting styles (authoritarian, authoritative, and pe...

  20. Parenting with style: altruism and paternalism in intergenerational preference transmission

    OpenAIRE

    Matthias Doepke; Fabrizio Zilibotti

    2014-01-01

    We develop a theory of intergenerational transmission of preferences that rationalizes the choice between alternative parenting styles (as set out in Baumrind 1967). Parents maximize an objective function that combines Beckerian altruism and paternalism towards children. They can affect their children’s choices via two channels: either by influencing children’s preferences or by imposing direct restrictions on their choice sets. Different parenting styles (authoritarian, authoritative, and pe...

  1. Parenting with style: altruism and paternalism in intergenerational preference transmission

    OpenAIRE

    Doepke, Matthias; Zilibotti, Fabrizio

    2014-01-01

    We develop a theory of intergenerational transmission of preferences that rationalizes the choice between alternative parenting styles (as set out in Baumrind 1967). Parents maximize an objective function that combines Beckerian altruism and paternalism towards children. They can affect their children's choices via two channels: either by influencing children's preferences or by imposing direct restrictions on their choice sets. Different parenting styles (authoritarian, authoritative, and pe...

  2. Parenting with Style: Altruism and Paternalism in Intergenerational Preference Transmission

    OpenAIRE

    Doepke, Matthias; Zilibotti, Fabrizio

    2014-01-01

    We develop a theory of intergenerational transmission of preferences that rationalizes the choice between alternative parenting styles (as set out in Baumrind 1967). Parents maximize an objective function that combines Beckerian altruism and paternalism towards children. They can affect their children's choices via two channels: either by influencing children's preferences or by imposing direct restrictions on their choice sets. Different parenting styles (authoritarian, authoritative, and pe...

  3. Load Distribution in Transmissions "Split"

    Science.gov (United States)

    Krantz, Timothy L.; Delgado, Irebert R.

    1998-01-01

    The transmission system of a helicopter must meet particularly critical requirements. It must transmit engine power to the rotor, at the same time ensuring a typical speed reduction of 60 to 1. It must also be safe, reliable, light, and reach a high level of performance while, at the same time, it must produce few vibrations and little noise. Helicopter transmissions have achieved high-level performances thanks to the combination of analyses, experiments, and the application of practical field experience. However, the new generation of helicopters will require transmission systems that are even safer, lighter, less noisy, and more reliable.

  4. Midwest Transmission Workshop I Summary

    Energy Technology Data Exchange (ETDEWEB)

    Kevin Bryan

    2001-05-01

    OAK-B135 The meeting was opened with a review of the purposes of the workshop: (1) Present and discuss key studies and assessments of transmission upgrades, additions and related issues for the upper Midwest, including work that addresses the full range of views on these topics; (2) Understand the various transmission issues in the upper Midwest and discuss options for addressing the issues; and (3) Identify the decision makers and entities that need to play an active role if transmission issues are to be resolved, and agree on next steps for engaging these individuals and organizations through education, outreach, and information dissemination.

  5. Dengue transmission based on urban environmental gradients in different cities of Pakistan.

    Science.gov (United States)

    Khalid, Bushra; Ghaffar, Abdul

    2015-03-01

    This study focuses on the dengue transmission in different regions of Pakistan. For this purpose, the data of dengue cases for 2009-2012 from four different cities (Rawalpindi, Islamabad, Lahore, and Karachi) of the country is collected, evaluated, and compiled. To identify the reasons and regions of higher risk of Dengue transmission, land use classification, analysis of climate covariates and drainage patterns was done. Analysis involves processing of SPOT 5 10 m, Landsat TM 30 m data sets, and SRTM 90 m digital elevation models by using remote sensing and GIS techniques. The results are based on the change in urbanization and population density, analysis of temperature, rainfall, and wind speed; calculation of drainage patterns including stream features, flow accumulation, and drainage density of the study areas. Results suggest that the low elevation areas with calm winds and minimum temperatures higher than the normal, rapid increase in unplanned urbanization, low flow accumulation, and higher drainage density areas favor the dengue transmission.

  6. [The control of the transmission by transfusion of Chagas' disease in the Southern Cone Initiative].

    Science.gov (United States)

    Dias, J C; Schofield, C J

    1998-01-01

    The Southern Cone Initiative against Chagas' disease, was launched in 1991. The aim was to interrupt the transmission of Chagas disease by elimination of domestic populations of the major vector, Triatoma infestans, and by improved screening of blood donors. As a result of these activities, a marked reduction in the risk of transfusional transmission can now be seen throughout the programme area. In addition to specific legislation concerning the quality of transfused blood, a series of national and regional reference laboratories have been set up with the help of PAHO in order to improve the quality of pre-transfusional serodiagnosis. Results indicate a progressive reduction in the overall infection prevalence of blood donors, and show that the age-prevalence curve has shifted towards older age-groups. In this paper we analyse the changes in infection prevalence in the Southern Cone countries, drawing attention to the situation in Bolivia which has the highest indices of infection and lowest levels of coverage by the control programme. In this situation chemoprophylaxis of blood prior to transfusion may be recommended in accordance with PAHO criteria. In the medium term however, interruption of human Chagas disease transmission may be expected over most of the Southern Cone region, as long as the control activities are continued and consolidated through effective epidemiological surveillance.

  7. 76 FR 58424 - Transmission Relay Loadability Reliability Standard

    Science.gov (United States)

    2011-09-21

    ... series capacitors and address circuit and transformer thermal capability. 19. Criterion 1 specifies... constraints, transformers are more limiting than other series elements with regard to through-fault capability... settings on (1) All transmission lines and transformers with low- voltage terminals operated or...

  8. Statistiscal Experimental Design for Quantitative Atomic Resolution Transmission Electron Microscopy

    NARCIS (Netherlands)

    Van Aert, S.

    2003-01-01

    Statistical experimental design is applied to set up quantitative atomic resolution transmission electron microscopy experiments. In such experiments, observations of the atomic structure of the object under study are always subject to spontaneous fluctuations. As a result of these fluctuations, the

  9. Parenting with style: Altruism and paternalism in intergenerational preference transmission

    OpenAIRE

    Doepke, Matthias; Zilibotti, Fabrizio

    2012-01-01

    We construct a theory of intergenerational preference transmission that rationalizes the choice between alternative parenting styles (related to Baumrind 1967). Parents maximize an objective function that combines Beckerian and paternalistic altruism towards children. They can affect their children's choices via two channels: either by influencing their preferences or by imposing direct restrictions on their choice sets. Different parenting styles (authoritarian, authoritative, and permissive...

  10. Parenting with Style: Altruism and Paternalism in Intergenerational Preference Transmission

    OpenAIRE

    Doepke, Matthias; Zilibotti, Fabrizio

    2012-01-01

    We construct a theory of intergenerational preference transmission that rationalizes the choice between alternative parenting styles (related to Baumrind 1967). Parents maximize an objective function that combines Beckerian and paternalistic altruism towards children. They can affect their children's choices via two channels: either by influencing their preferences or by imposing direct restrictions on their choice sets. Different parenting styles (authoritarian, authoritative, and permissive...

  11. 18 CFR 35.34 - Regional Transmission Organizations.

    Science.gov (United States)

    2010-04-01

    ... accommodates the open architecture condition set forth in paragraph (l) of this section. (2) Market participant... development and operation of market mechanisms to manage transmission congestion. As part of its demonstration... satisfy the market mechanism requirement no later than one year after it commences initial...

  12. Local structure of self-affine sets

    CERN Document Server

    Bandt, Christoph

    2011-01-01

    The structure of a self-similar set with open set condition does not change under magnification. For self-affine sets the situation is completely different. We consider planar self-affine Cantor sets E of the type studied by Bedford, McMullen, Gatzouras and Lalley, for which the projection onto the horizontal axis is an interval. We show that within small square neighborhoods of almost each point x in E, with respect to many product measures on address space, E is well approximated by product sets of an interval and a Cantor set. Even though E is totally disconnected, the limit sets have the product structure with interval fibres, reminiscent to the view of attractors of chaotic differentiable dynamical systems.

  13. Asset life and pricing the use of electricity transmission infrastructure in Chile

    Energy Technology Data Exchange (ETDEWEB)

    Raineri, Ricardo [Pontificia Universidad Catolica de Chile, Av. Vicuna Mackenna 4860, Santiago (Chile)

    2010-01-15

    Beyond the different approaches to set regulated prices for the use of infrastructure, a key parameter to determine regulated tariffs is the concept of asset life and how it changes with changes in the economic and regulatory context, which determines the optimal infrastructure investment and replacement policies. In this paper we look at the effects that changes in demand, the presence of substitutes and complements, the regulatory framework - both a pro or an anticompetitive framework -, scale economies, and the investment planning horizon, have on the economic service life of an asset and the tariffs for its use. We find that as the electric industry becomes more competitive, a negative effect on the economic service life of electric electricity transmission should be expected. Also, numerical experiments illustrate an inverse relation between scale economies on investment and the ESL of electricity transmission infrastructure. Further, we look at the biases on optimal investment that happen when optimal plans do not observe the life cycle of the investments and the ESL of the equipment, as well as the inconsistency and biases on optimal investment and replacement policies that might result when the Social Planner optimal investment plan lacks of a long-term commitment. (author)

  14. Similar dissection of sets

    CERN Document Server

    Akiyama, Shigeki; Okazaki, Ryotaro; Steiner, Wolfgang; Thuswaldner, Jörg

    2010-01-01

    In 1994, Martin Gardner stated a set of questions concerning the dissection of a square or an equilateral triangle in three similar parts. Meanwhile, Gardner's questions have been generalized and some of them are already solved. In the present paper, we solve more of his questions and treat them in a much more general context. Let $D\\subset \\mathbb{R}^d$ be a given set and let $f_1,...,f_k$ be injective continuous mappings. Does there exist a set $X$ such that $D = X \\cup f_1(X) \\cup ... \\cup f_k(X)$ is satisfied with a non-overlapping union? We prove that such a set $X$ exists for certain choices of $D$ and $\\{f_1,...,f_k\\}$. The solutions $X$ often turn out to be attractors of iterated function systems with condensation in the sense of Barnsley. Coming back to Gardner's setting, we use our theory to prove that an equilateral triangle can be dissected in three similar copies whose areas have ratio $1:1:a$ for $a \\ge (3+\\sqrt{5})/2$.

  15. Oral Transmission: A Marriage of Music, Language, Tradition, and Culture

    Directory of Open Access Journals (Sweden)

    Emma E. Patterson

    2015-06-01

    Full Text Available There are a number of misunderstandings about ancient oral transmission that negatively affect the way musicians view music history but also the process of how music was and currently is conceived, recorded, and shared. A common misconception is that oral transmission of music is an ancient practice that occurred before written notation of music was developed. However, I seek to prove that there is a false dichotomy between oral transmission and written notation and I focus on the changing definition and importance of oral tradition. Firstly, I discuss the misconceptions of ancient oral transmission. Secondly, I examine the continuing development of research and definitions of oral transmission—which is changing our concept of ancient as well contemporary oral traditions. Thirdly, I demonstrate how these traditions are still relevant in present, late modern times. Thoughout this discussion I examine and engage with the pivotal specialists and research that has developed our view of oral tradition through time. To better understand these scholars’ commentary as well as my own, it is important to note the combined concepts of oral and aural tradition. Oral culture refers to what is spoken and sung, and aural culture refers to what is heard and comprehended. Both are necessary for effective transmission to occur, and oral and aural methods are almost always simultaneously present in most societies. When aural culture is discussed here, it refers to the combination of both elements and is closely related to aural tradition. The most notable terms to differentiate are oral transmission and oral tradition. Typically oral transmission refers to the basic action of passing information, in this case music, through oral and aural means. Oral tradition, however, is the more general concept that synthesizes oral transmission, tradition, and culture. Despite misconceptions that music was primitive before composers started documenting it, oral

  16. Following the Rules Set by Accreditation Agencies and Governing Bodies to Maintain In-Compliance Status: Applying Critical Thinking Skills When Evaluating the Need for Change in the Clinical Laboratory.

    Science.gov (United States)

    Byrne, Karen M; Levy, Kimberly Y; Reese, Erika M

    2016-05-01

    Maintaining an in-compliance clinical laboratory takes continuous awareness and review of standards, regulations, and best practices. A strong quality assurance program and well informed leaders who maintain professional networks can aid in this necessary task. This article will discuss a process that laboratories can follow to interpret, understand, and comply with the rules and standards set by laboratory accreditation bodies.

  17. 传动机构的设计与计算%Design and calculation of the transmission mechanism

    Institute of Scientific and Technical Information of China (English)

    杨倩倩; 姚竹亭

    2015-01-01

    机械传动机构,可以将动力所提供的运动方式、方向或速度加以改变,被人们有目的地利用。机械传动分为很多种,例如丝杠传动、齿轮传动、链传动、带轮传动、蜗轮蜗杆传动等。本文将以同步带传动为例,设计一个传动机构。%Mechanical transmission mechanism could change movement, direction or speed provided by the power which used for a set purpose. Mechanical drive is divided into many kinds, such as lead screw drive, gear drive, chain drive, pulley drive, worm gearing. In this paper, a transmission mechanism is designed in a case study of synchronous belt drive.

  18. The Model Confidence Set

    DEFF Research Database (Denmark)

    Hansen, Peter Reinhard; Lunde, Asger; Nason, James M.

    The paper introduces the model confidence set (MCS) and applies it to the selection of models. A MCS is a set of models that is constructed such that it will contain the best model with a given level of confidence. The MCS is in this sense analogous to a confidence interval for a parameter. The MCS......, beyond the comparison of models. We apply the MCS procedure to two empirical problems. First, we revisit the inflation forecasting problem posed by Stock and Watson (1999), and compute the MCS for their set of inflation forecasts. Second, we compare a number of Taylor rule regressions and determine...... the MCS of the best in terms of in-sample likelihood criteria....

  19. Enlargements of positive sets

    CERN Document Server

    Bot, Radu Ioan

    2008-01-01

    In this paper we introduce the notion of enlargement of a positive set in SSD spaces. To a maximally positive set $A$ we associate a family of enlargements $\\E(A)$ and characterize the smallest and biggest element in this family with respect to the inclusion relation. We also emphasize the existence of a bijection between the subfamily of closed enlargements of $\\E(A)$ and the family of so-called representative functions of $A$. We show that the extremal elements of the latter family are two functions recently introduced and studied by Stephen Simons. In this way we extend to SSD spaces some former results given for monotone and maximally monotone sets in Banach spaces.

  20. Transmission line model for nanoelectronics

    Directory of Open Access Journals (Sweden)

    Nelin E. A.

    2009-08-01

    Full Text Available Analytical expressions for resonant parametres and characteristics of typical barrier nanoelectronic structures have been received on the basis of the transmission line model. Characteristics illustrating the efficiency of such approach are presented in the article.

  1. Hybrid-Vehicle Transmission System

    Science.gov (United States)

    Lupo, G.; Dotti, G.

    1985-01-01

    Continuously-variable transmission system for hybrid vehicles couples internal-combustion engine and electric motor section, either individually or in parallel, to power vehicle wheels during steering and braking.

  2. Cultural transmission of civic attitudes.

    Science.gov (United States)

    Miles-Touya, Daniel; Rossi, Máximo

    2016-01-01

    In this empirical paper we attempt to measure the separate influence on civic engagement of educational attainment and cultural transmission of civic attitudes. Unlike most of the previous empirical works on this issue, we are able to approximate the cultural transmission of civic attitudes. We observe that civic returns to education are overstated when the transmission of civic attitudes is ignored. Moreover, the transmission of civic attitudes significantly enhances civic involvement and reinforces civic returns to education. Our findings are in line with the proposals of civic virtue theorists or grass movements who suggest that citizenship education should be included in the compulsory school curricula since, if not, families or local communities will only transmit their particular view of the world.

  3. Infection prevention and control for HIV and other infectious agents in obstetric, gynecologic and neonatal settings.

    Science.gov (United States)

    Jackson, M M

    1990-01-01

    Personnel working in obstetric and gynecologic settings have long recognized their increased risks for infection with the hepatitis B virus and many have been immunized with hepatitis B vaccine. Staphylococcus aureus cross-transmission among neonates in newborn nurseries in the 1950s was a major impetus for the development of hospital infection control programs. In recent years, however, it is concerns about infection with the human immunodeficiency virus (HIV) that have caused health care workers and hospitals to rethink traditional infection risk reduction strategies and change them. This article describes infection risks peculiar to obstetric, gynecologic, and neonatal settings and presents practical approaches for reducing these risks, both for patients and for health care workers.

  4. Combinatorics of finite sets

    CERN Document Server

    Anderson, Ian

    2011-01-01

    Coherent treatment provides comprehensive view of basic methods and results of the combinatorial study of finite set systems. The Clements-Lindstrom extension of the Kruskal-Katona theorem to multisets is explored, as is the Greene-Kleitman result concerning k-saturated chain partitions of general partially ordered sets. Connections with Dilworth's theorem, the marriage problem, and probability are also discussed. Each chapter ends with a helpful series of exercises and outline solutions appear at the end. ""An excellent text for a topics course in discrete mathematics."" - Bulletin of the Ame

  5. Setting goals in psychotherapy

    DEFF Research Database (Denmark)

    Emiliussen, Jakob; Wagoner, Brady

    2013-01-01

    The present study is concerned with the ethical dilemmas of setting goals in therapy. The main questions that it aims to answer are: who is to set the goals for therapy and who is to decide when they have been reached? The study is based on four semi-­‐structured, phenomenological interviews...... that are based on asymmetric collaboration between the therapist and the client. Determining goals and deciding when they are reached are not “sterile” procedures, as both the client and the therapist might have different agendas when working therapeutically. The psychologists that participated in this study...

  6. Why quasi-sets?

    Directory of Open Access Journals (Sweden)

    Décio Krause

    2002-11-01

    Full Text Available Quasi-set theory was developed to deal with collections of indistinguishable objects. In standard mathematics, there are no such kind of entities, for indistinguishability (agreement with respect to all properties entails numerical identity. The main motivation underlying such a theory is of course quantum physics, for collections of indistinguishable (’identical’ in the physicists’ jargon particles cannot be regarded as ’sets’ of standard set theories, which are collections of distinguishable objects. In this paper, a rationale for the development of such a theory is presented, motivated by Heinz Post’s claim that indistinguishability ofquantum entities should be attributed ’right at the start’.

  7. Set theory and logic

    CERN Document Server

    Stoll, Robert R

    1979-01-01

    Set Theory and Logic is the result of a course of lectures for advanced undergraduates, developed at Oberlin College for the purpose of introducing students to the conceptual foundations of mathematics. Mathematics, specifically the real number system, is approached as a unity whose operations can be logically ordered through axioms. One of the most complex and essential of modern mathematical innovations, the theory of sets (crucial to quantum mechanics and other sciences), is introduced in a most careful concept manner, aiming for the maximum in clarity and stimulation for further study in

  8. Nonmeasurable sets and functions

    CERN Document Server

    Kharazishvili, Alexander

    2004-01-01

    The book is devoted to various constructions of sets which are nonmeasurable with respect to invariant (more generally, quasi-invariant) measures. Our starting point is the classical Vitali theorem stating the existence of subsets of the real line which are not measurable in the Lebesgue sense. This theorem stimulated the development of the following interesting topics in mathematics:1. Paradoxical decompositions of sets in finite-dimensional Euclidean spaces;2. The theory of non-real-valued-measurable cardinals;3. The theory of invariant (quasi-invariant)extensions of invariant (quasi-invaria

  9. On Random Rough Sets

    Institute of Scientific and Technical Information of China (English)

    Weizhi Wu

    2006-01-01

    In this paper,the concept of a random rough set which includes the mechanisms of numeric and non-numeric aspects of uncertain knowledge is introduced. It is proved that for any belief structure and its inducing belief and plausibility measures there exists a random approximation space such that the associated lower and upper probabilities are respectively the given belief and plausibility measures, and vice versa. And for a random approximation space generated from a totally random set, its inducing lower and upper probabilities are respectively a pair of necessity and possibility measures.

  10. Radio and line transmission 2

    CERN Document Server

    Roddy, Dermot

    2013-01-01

    Radio and Line Transmission, Volume 2 gives a detailed treatment of the subject as well as an introduction to additional advanced subject matter. Organized into 14 chapters, this book begins by explaining the radio wave propagation, signal frequencies, and bandwidth. Subsequent chapters describe the transmission lines and cables; the aerials; tuned and coupled circuits; bipolar transistor amplifiers; field-effect transistors and circuits; thermionic valve amplifiers; LC oscillators; the diode detectors and modulators; and the superheterodyne receiver. Other chapters explore noise and interfere

  11. Optimal Energy-Efficient Downlink Transmission Scheduling for Real-Time Wireless Networks

    OpenAIRE

    Miao, Lei; Mao, Jianfeng; Cassandras, Christos G.

    2016-01-01

    It has been shown that using appropriate channel coding schemes in wireless environments, transmission energy can be significantly reduced by controlling the packet transmission rate. This paper seeks optimal solutions for downlink transmission control problems, motivated by this observation and by the need to minimize energy consumption in real-time wireless networks. Our problem formulation deals with a more general setting than the paper authored by Gamal et. al., in which the MoveRight al...

  12. EXTERNAL FACTORS FOR THE MONETARY POLICY TRANSMISSION MECHANISM

    Directory of Open Access Journals (Sweden)

    Dan Horatiu

    2013-07-01

    Full Text Available This paper reviews and analyzes the effects that external (or exogenous factors, defined as economic factors that cannot be controlled or influenced by the central bank, have on monetary policy and the monetary policy transmission mechanism. Adopting a theoretical research position, we aim at identifying the main external factors to monetary policy and discuss the ways in which these factors alter the economic environment and implicitly the monetary policy transmission mechanism. This is done by changing the way in which monetary transmission channels work and deliver monetary policy decisions throughout the economy, with the final goal of producing central bank desired outcomes with regard to economic variables like inflation, employment, or the production level. We will begin this article with a brief introduction on the topic of monetary policy, the monetary policy transmission mechanism and the potential external factors that may influence the monetary policy and the functioning of its transmission mechanism. The main external factors are identified as linked to fiscal policy, commodity prices, financial market volatility or other globalization related processes. After this introduction, we will proceed with the analysis of the nature and influences of each of the above mentioned external factors on monetary policy and its transmission, indentifying the potential ways in which they can change the structure and internal processes of the transmission channels. As we will see in the study and highlight in our conclusion, the external factors cause decisive changes in the way monetary policy is transmitted, and thus will strongly influence the decisions that central banks take in order to alter key economic variables. The profound understanding of how these non-central bank controlled factors influence the monetary policy transmission mechanism is a key requirement for central banks, as only by being able to predict, recognize and evaluate the

  13. Temporal variability and social heterogeneity in disease transmission: the case of SARS in Hong Kong.

    Directory of Open Access Journals (Sweden)

    Anne Cori

    2009-08-01

    Full Text Available The extent to which self-adopted or intervention-related changes in behaviors affect the course of epidemics remains a key issue for outbreak control. This study attempted to quantify the effect of such changes on the risk of infection in different settings, i.e., the community and hospitals. The 2002-2003 severe acute respiratory syndrome (SARS outbreak in Hong Kong, where 27% of cases were healthcare workers, was used as an example. A stochastic compartmental SEIR (susceptible-exposed-infectious-removed model was used: the population was split into healthcare workers, hospitalized people and general population. Super spreading events (SSEs were taken into account in the model. The temporal evolutions of the daily effective contact rates in the community and hospitals were modeled with smooth functions. Data augmentation techniques and Markov chain Monte Carlo (MCMC methods were applied to estimate SARS epidemiological parameters. In particular, estimates of daily reproduction numbers were provided for each subpopulation. The average duration of the SARS infectious period was estimated to be 9.3 days (+/-0.3 days. The model was able to disentangle the impact of the two SSEs from background transmission rates. The effective contact rates, which were estimated on a daily basis, decreased with time, reaching zero inside hospitals. This observation suggests that public health measures and possible changes in individual behaviors effectively reduced transmission, especially in hospitals. The temporal patterns of reproduction numbers were similar for healthcare workers and the general population, indicating that on average, an infectious healthcare worker did not infect more people than any other infectious person. We provide a general method to estimate time dependence of parameters in structured epidemic models, which enables investigation of the impact of control measures and behavioral changes in different settings.

  14. Advanced Rotorcraft Transmission (ART) program

    Science.gov (United States)

    Heath, Gregory F.; Bossler, Robert B., Jr.

    1993-01-01

    Work performed by the McDonnell Douglas Helicopter Company and Lucas Western, Inc. within the U.S. Army/NASA Advanced Rotorcraft Transmission (ART) Program is summarized. The design of a 5000 horsepower transmission for a next generation advanced attack helicopter is described. Government goals for the program were to define technology and detail design the ART to meet, as a minimum, a weight reduction of 25 percent, an internal noise reduction of 10 dB plus a mean-time-between-removal (MTBR) of 5000 hours compared to a state-of-the-art baseline transmission. The split-torque transmission developed using face gears achieved a 40 percent weight reduction, a 9.6 dB noise reduction and a 5270 hour MTBR in meeting or exceeding the above goals. Aircraft mission performance and cost improvements resulting from installation of the ART would include a 17 to 22 percent improvement in loss-exchange ratio during combat, a 22 percent improvement in mean-time-between-failure, a transmission acquisition cost savings of 23 percent of $165K, per unit, and an average transmission direct operating cost savings of 33 percent, or $24K per flight hour. Face gear tests performed successfully at NASA Lewis are summarized. Also, program results of advanced material tooth scoring tests, single tooth bending tests, Charpy impact energy tests, compact tension fracture toughness tests and tensile strength tests are summarized.

  15. The Intergenerational Transmission of the Value of Children in Contemporary Chinese Families: Taiwan and Mainland China Compared

    Directory of Open Access Journals (Sweden)

    Chin-Chun Yi

    2014-10-01

    Full Text Available Dieser Beitrag liegt nur in englischer Sprache vor.While fertility has been drastically declining in East Asia, mechanisms accounting for the current trend vary. One noticeable mechanism documented is that the changing value of children affects couples’ fertility decisions which in turn affect their subsequent fertility behaviour. This study will examine the intergenerational transmission of the value of children (VOC among grandmothers, mothers and teenagers in two Chinese societies: Taiwan and Mainland China. We assume that cultural homogeneity interacts with political and social heterogeneity and may result in different values regarding having or not having children. Data are taken from two corresponding VOC surveys from Taiwan (2005-2007 and from Mainland China (2002-2003. We first compare the value of children for Taiwan and Mainland China with special attention to cultural aspects. Two identified factor solutions are generated for both positive (traditional and emotional and negative (emotional/psychological and familial/social VOC. Analyses show that intergenerational transmission of the VOC among three generations is more likely to occur for a positive VOC in the Chinese Mainland sample. We suspect that actual fertility experience results in greater resemblance on the VOC between grandmothers and mothers in both research settings. Among selected structural mechanisms, only rural-urban background has an effect on patterns of intergenerational transmission. The paper ends with a discussion on the importance of culture in explaining the intergenerational transmission of the VOC in Chinese societies.

  16. Essays on electricity transmission investment and financial transmission rights

    Science.gov (United States)

    Shang, Wenzhuo

    The U.S. electric power industry has been going through fundamental restructuring and realignment since the 1990's. Many issues and problems have emerged during the transition, and both economists and engineers have been looking for the solutions fervently. In this dissertation, which consists primarily of three essays, we apply economics theory and techniques to the power industry and address two related issues, transmission investment and financial transmission rights (FTRs). The first essay takes the decentralized perspective and investigates the efficiency attribute of market-based transmission investment under perfect competition. We clarify, for the first time, the nature of the externality created by loop flows that causes transmission investment to be inefficient. Our findings have important implications for better understanding of transmission market design and creating incentives for efficient transmission investment. In the second essay, we define several rules for allocating transmission investment cost within the framework of cooperative game theory. These rules provide fair, stable or efficient cost allocations in theory and are good benchmarks against which the allocation mechanism in practice can be compared and improved upon. In the last essay, we make exploratory efforts in analyzing and assessing empirically the performance of the Midwest independent system operator (MISO) FTR auction market. We reveal some stylized facts about this young market and find that it is not efficient under the risk-neutrality assumption. We also point out and correct the drawbacks in previous related work and suggest about more complete empirical work in future. In all, this dissertation makes both theoretic and empirical analysis of the two hot issues related to the power industry and comes up with findings that have important implications for the development of this industry.

  17. Infrared Transmission Spectra for Extrasolar Giant Planets

    CERN Document Server

    Tinetti, G; Vidal-Madjar, A; Ehrenreich, D; Etangs, A L; Yung, Y

    2006-01-01

    Among the hot Jupiters that transit their parent stars known to date, the two best candidates to be observed with transmission spectroscopy in the mid-infrared (MIR) are HD189733b and HD209458b, due to their combined characteristics of planetary density, orbital parameters and parent star distance and brightness. Here we simulate transmission spectra of these two planets during their primary eclipse in the MIR, and we present sensitivity studies of the spectra to the changes of atmospheric thermal properties, molecular abundances and C/O ratios. Our model predicts that the dominant species absorbing in the MIR on hot Jupiters are water vapor and carbon monoxide, and their relative abundances are determined by the C/O ratio. Since the temperature profile plays a secondary role in the transmission spectra of hot Jupiters compared to molecular abundances, future primary eclipse observations in the MIR of those objects might give an insight on EGP atmospheric chemistry. We find here that the absorption features c...

  18. Ready, set...go!

    Energy Technology Data Exchange (ETDEWEB)

    Alexandre, Melanie

    2010-06-16

    The objectives of this paper are: (1) Discuss organizational readiness for changes in an ergonomics program or intervention; (2) Assessing organizational readiness; (3) Benefits and challenges of change; and (4) Case studies of ergonomic programs that were 'not ready' and 'ready'.

  19. Transmission line sag calculations using interval mathematics

    Energy Technology Data Exchange (ETDEWEB)

    Shaalan, H. [Institute of Electrical and Electronics Engineers, Washington, DC (United States)]|[US Merchant Marine Academy, Kings Point, NY (United States)

    2007-07-01

    Electric utilities are facing the need for additional generating capacity, new transmission systems and more efficient use of existing resources. As such, there are several uncertainties associated with utility decisions. These uncertainties include future load growth, construction times and costs, and performance of new resources. Regulatory and economic environments also present uncertainties. Uncertainty can be modeled based on a probabilistic approach where probability distributions for all of the uncertainties are assumed. Another approach to modeling uncertainty is referred to as unknown but bounded. In this approach, the upper and lower bounds on the uncertainties are assumed without probability distributions. Interval mathematics is a tool for the practical use and extension of the unknown but bounded concept. In this study, the calculation of transmission line sag was used as an example to demonstrate the use of interval mathematics. The objective was to determine the change in cable length, based on a fixed span and an interval of cable sag values for a range of temperatures. The resulting change in cable length was an interval corresponding to the interval of cable sag values. It was shown that there is a small change in conductor length due to variation in sag based on the temperature ranges used in this study. 8 refs.

  20. Teacher Education beyond Transmission: Challenges and Opportunities for Iranian Teachers of English

    Science.gov (United States)

    Safari, Parvin; Rashidi, Nasser

    2015-01-01

    The teacher education field has recently undergone dramatic changes leading to a shift of focus from transmission models towards alternative approaches and theories that emerged in the post-transmission era addressing sociocultural, political, ideological, and critical issues. Despite worldwide changes in teacher education programs, it seems that…